WorldWideScience

Sample records for selection qualification requirements

  1. 22 CFR 139.5 - Qualifications required for selection as a trainee.

    Science.gov (United States)

    2010-04-01

    ... CULTURAL AND TRAINING PROGRAM § 139.5 Qualifications required for selection as a trainee. To be a program... certification; and (c) Meet United States immigration/visa requirements, including being in receipt of a job...” prepared by the Program Administrator in consultation with the Department of State and the Immigration and...

  2. Sport Management Interns--Selection Qualifications.

    Science.gov (United States)

    Cuneen, Jacquelyn; Sidwell, M. Joy

    1993-01-01

    Examines and rates the background qualifications and qualities, identified by sport management practitioners through an examination of paper credentials, that are desired in interviewees vying for selection into sport management internship positions. (GLR)

  3. Policies and practices pertaining to the selection, qualification requirements, and training programs for nuclear-reactor operating personnel at the Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Culbert, W.H.

    1985-10-01

    This document describes the policies and practices of the Oak Ridge National Laboratory (ORNL) regarding the selection of and training requirements for reactor operating personnel at the Laboratory's nuclear-reactor facilities. The training programs, both for initial certification and for requalification, are described and provide the guidelines for ensuring that ORNL's research reactors are operated in a safe and reliable manner by qualified personnel. This document gives an overview of the reactor facilities and addresses the various qualifications, training, testing, and requalification requirements stipulated in DOE Order 5480.1A, Chapter VI (Safety of DOE-Owned Reactors); it is intended to be in compliance with this DOE Order, as applicable to ORNL facilities. Included also are examples of the documentation maintained amenable for audit.

  4. INDUSTRIAL RESTRUCTURING AND PROFESSIONAL QUALIFICATION REQUIREMENTS

    Directory of Open Access Journals (Sweden)

    João Amato Neto

    2014-09-01

    Full Text Available Among the most complex subjects that affect modern society in this early millennium, the problem of relationships between the educational patterns and the work organization seems to be one of the most important and full of uncertainties. Specially, this problem acquires greater relevance when one thinks of the impacts of the techno-scientific revolution in the work world, as well as in the educational system. In this sense, the present work researches some elements regarding the new educational patterns and qualification requirements in face of the new industrial paradigm and discusses the transformations accomplished by the techno-scientific revolution and its implications on the new lean and flexible production paradigm and on the (reorganization of work in the modern industry. The methodological approach is based on a bibliographic revision with a quantitative approach.

  5. 14 CFR 121.437 - Pilot qualification: Certificates required.

    Science.gov (United States)

    2010-01-01

    ... Pilot qualification: Certificates required. (a) No pilot may act as pilot in command of an aircraft (or... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot qualification: Certificates required... TRANSPORTATION (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS...

  6. 77 FR 12373 - Pilot Certification and Qualification Requirements for Air Carrier Operations

    Science.gov (United States)

    2012-02-29

    ..., 135, et al. Pilot Certification and Qualification Requirements for Air Carrier Operations; Proposed...-AJ67 Pilot Certification and Qualification Requirements for Air Carrier Operations AGENCY: Federal...: For technical questions concerning this proposed rule contact Barbara Adams, Aircraft Certification...

  7. 78 FR 53025 - Pilot Certification and Qualification Requirements for Air Carrier Operations; Correction

    Science.gov (United States)

    2013-08-28

    ... regulations to create new certification and qualification requirements for pilots in air carrier operations..., the FAA published a final rule entitled, ``Pilot Certification and Qualification Requirements for Air... Federal Aviation Administration 14 CFR Part 141 RIN 2120-AJ67 Pilot Certification and Qualification...

  8. Significance of ITER IWS Material Selection and Qualification

    Science.gov (United States)

    Mehta, Bhoomi K.; Raval, Jigar; Maheshwari, Abha; Laad, Rahul; Singh, Gurlovleen; Pathak, Haresh

    2017-04-01

    In-Wall Shielding (IWS) is one of the important components of ITER Vacuum Vessel (VV) which fills the space between double walls of VV with cooling water. Procurement Arrangement (PA) for IWS has been signed with Indian Domestic Agency (INDA). Procurement of IWS materials, fabrication of IWS blocks and its delivery to respective Domestic Agency (DA) and ITER Organization (IO) are the main scope of this PA. Hence, INDIA is the only country which is contributing to VV IWS among all seven ITER partners. The main functions of the IWS are to provide Neutron Shielding with blanket, VV shells and water during plasma operations and to reduce ripple of the Toroidal Magnetic Field. To meet these functional requirements IWS blocks are made up of special materials (Borated Steels SS304 B4 & SS304 B7, Ferritic Steels SS 430, Austenitic Steel SS 316 L (N)-IG, XM-19 and Inconel-625) which are qualified, reliable and traceable for the design assessment. The choice of these materials has a significant influence on performance, maintainability, licensing, detailed design parameters and waste disposal. The main reasons for the materials selected for IWS are its high mechanical strength at operating temperatures, water chemistry properties, excellent fabrication characteristics and low cost relative to other similar materials. All the materials are qualified with respect to their respective codes (ASTM/EN standards with additional requirements as described in RCC-MR code 2007) and ITER requirements. Agreed Notified Body (ANB) has control conformity of materials certificates with approved material specification and traceability procedure for Safety Important Component (SIC). The procurement strategy for all the IWS materials has been developed in close collaboration with IO, ANB and Industries as per Product Procurement Specification (PPS). The R&D for sample, bulk material production, testing, inspection and handling as required are carried out by IN DA and IO. At present almost all

  9. 78 FR 77572 - Pilot Certification and Qualification Requirements for Air Carrier Operations; Technical Amendment

    Science.gov (United States)

    2013-12-24

    ... certification and qualification requirements for pilots in air carrier operations. The FAA unintentionally... published a final rule entitled, ``Pilot Certification and Qualification Requirements for Air Carrier... Federal Aviation Administration 14 CFR Parts 61, 121, and 135 RIN 2120-AJ67 Pilot Certification and...

  10. Instructions for Plastic Encapsulated Microcircuit(PEM) Selection, Screening and Qualification.

    Science.gov (United States)

    King, Terry; Teverovsky, Alexander; Leidecker, Henning

    2002-01-01

    The use of Plastic Encapsulated Microcircuits (PEMs) is permitted on NASA Goddard Space Flight Center (GSFC) spaceflight applications, provided each use is thoroughly evaluated for thermal, mechanical, and radiation implications of the specific application and found to meet mission requirements. PEMs shall be selected for their functional advantage and availability, not for cost saving; the steps necessary to ensure reliability usually negate any initial apparent cost advantage. A PEM shall not be substituted for a form, fit and functional equivalent, high reliability, hermetic device in spaceflight applications. Due to the rapid change in wafer-level designs typical of commercial parts and the unknown traceability between packaging lots and wafer lots, lot specific testing is required for PEMs, unless specifically excepted by the Mission Assurance Requirements (MAR) for the project. Lot specific qualification, screening, radiation hardness assurance analysis and/or testing, shall be consistent with the required reliability level as defined in the MAR. Developers proposing to use PEMs shall address the following items in their Performance Assurance Implementation Plan: source selection (manufacturers and distributors), storage conditions for all stages of use, packing, shipping and handling, electrostatic discharge (ESD), screening and qualification testing, derating, radiation hardness assurance, test house selection and control, data collection and retention.

  11. 78 FR 44873 - Pilot Certification and Qualification Requirements for Air Carrier Operations; Correction

    Science.gov (United States)

    2013-07-25

    ...--International Law, Legislation, and Regulations Division, AGC-240, Federal Aviation Administration, 800... Federal Aviation Administration 14 CFR Part 61 RIN 2120-AJ67 Pilot Certification and Qualification Requirements for Air Carrier Operations; Correction AGENCY: Federal Aviation Administration, DOT. ACTION: Final...

  12. The recertification of the professional accounting qualification in Estonia: the requirements and quality of CPD

    Directory of Open Access Journals (Sweden)

    Kaidi Kallaste

    2017-09-01

    Full Text Available The recertification of the professional accounting qualification in Estonia: the requirements and quality of CPD As the purpose of a professional qualification should be to ensure quality to employers/customers, appro-priate requirements for professional training should not be too low. On the other hand, too high require-ments for the amount of training would lead to the situation where maintaining the level is expensive and if the labour market does not consider having a professional certificate necessary, recertification will be discarded. The purpose of the research was to identify the factors that influence an accountant’s decision whether to recertify his/her professional qualification or not. The conditions of recertification were ana-lysed and compared to other countries as were the requirements set up for auditors. The results of the survey revealed that in Estonia the decision not to recertify one’s professional qualification was mainly due to not having fulfilled the required number of qualification hours or not having certificates proving one’s participation in qualification training sessions. At the same time, compared to other countries, the requirements in Estonia are very low. So that the increase in the amount of training would not hinder recertification, alternative solutions for Estonia are proposed in the article.

  13. The Impact of Information Technology on Job Requirements and Qualifications for Catalogers.

    Science.gov (United States)

    Khurshid, Zahiruddin

    2003-01-01

    Reviews job advertisements published in "American Libraries" and "College and Research Libraries News" to assess the impact of the use of information technology in libraries on job requirements and qualifications for catalogers. Examines position titles, degree requirements, and required skills, and suggests implications for…

  14. Standard guide for the selection, training and qualification of nondestructive assay (NDA) personnel

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2004-01-01

    1.1 This guide contains good practices for the selection, training, qualification, and professional development of personnel performing analysis, calibration, physical measurements, or data review using nondestructive assay equipment, methods, results, or techniques. The guide also covers NDA personnel involved with NDA equipment setup, selection, diagnosis, troubleshooting, or repair. Selection, training, and qualification programs based on this guide are intended to provide assurance that NDA personnel are qualified to perform their jobs competently. This guide presents a series of options but does not recommend a specific course of action.

  15. Required qualifications in the Swedish Public Dental Health Service as indicators of organizational ideology.

    Science.gov (United States)

    Franzén, C; Söderfeldt, B

    2001-12-01

    The manifestly required qualifications in job advertisements in the Journal of the Swedish Dental Association were analyzed as indicators of the organizational ideology in the Swedish Public Dental Health Service from the employers' viewpoint. All job advertisements that concerned dentists and managers on different hierarchical levels in general dentistry from January 1990 to December 1998 were included (n = 1152). The number of vacancies was 1856. The textual material was analyzed by content analysis, permitting quantitative descriptions of the text and analysis of the latent characteristics. Words and phrases were classified into categories on different levels of abstraction developed from the theoretical background and the purpose of the study. Altogether 5705 required qualifications were categorized. The inter-coder reliability of the first-level categorization resulted in 81% correspondence of the classification, and lambda = 0.90. Qualifications were more frequently required with higher hierarchical job positions, and personality characteristics were more frequent than technical competence and knowledge. Qualifications interpreted as related to economic goals occurred more frequently than those related to odontological goals. The qualification demands reflected the language of human resource management (HRM), emphasizing the 'soft' people-centered approach and was interpreted as an 'ideal' model of HRM. Dentists were regarded as a profitable organizational asset rather than participants in relations with patients. In conclusion, the results indicate an organizational ideology primarily of economic character.

  16. International Space Station (ISS) Internal Active Thermal Control System (IATCS) New Biocide Selection, Qualification and Implementation

    Science.gov (United States)

    Wilson, Mark E.; Cole, Harold E.; Rector, Tony; Steele, John; Varsik, Jerry

    2011-01-01

    The Internal Active Thermal Control System (IATCS) aboard the International Space Station (ISS) is primarily responsible for the removal of heat loads from payload and system racks. The IATCS is a water based system which works in conjunction with the EATCS (External ATCS), an ammonia based system, which are interfaced through a heat exchanger to facilitate heat transfer. On-orbit issues associated with the aqueous coolant chemistry began to occur with unexpected increases in CO2 levels in the cabin. This caused an increase in total inorganic carbon (TIC), a reduction in coolant pH, increased corrosion, and precipitation of nickel phosphate. These chemical changes were also accompanied by the growth of heterotrophic bacteria that increased risk to the system and could potentially impact crew health and safety. Studies were conducted to select a biocide to control microbial growth in the system based on requirements for disinfection at low chemical concentration (effectiveness), solubility and stability, material compatibility, low toxicity to humans, compatibility with vehicle environmental control and life support systems (ECLSS), ease of application, rapid on-orbit measurement, and removal capability. Based on these requirements, ortho-phthalaldehyde (OPA), an aromatic dialdehyde compound, was selected for qualification testing. This paper presents the OPA qualification test results, development of hardware and methodology to safely apply OPA to the system, development of a means to remove OPA, development of a rapid colorimetric test for measurement of OPA, and the OPA on-orbit performance for controlling the growth of microorganisms in the ISS IATCS since November 3, 2007.

  17. DOE handbook: Guide to good practices for the selection, training, and qualification of shift supervisors

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    This Department of Energy (DOE) handbook is approved for use by all DOE Components and their contractors. The Handbook incorporates editorial changes to DOE-STD-1061-93, ``Guide to Good Practices for the Selection, Training, and Qualification of shift Supervisors,`` and supersedes DOE-STD-1061-93. Technical content of this Handbook has not changed from the original technical standard. Changes are primarily editorial improvements, redesignation of the standard to a Handbook, and format changes to conform with current Technical Standards Program procedures. This guide, used in conjunction with a facility-specific job analysis, provides a framework for the selection, training, qualification, and professional development of reactor facility and non-reactor nuclear facility shift supervisors. Training and qualification programs based on this guide should provide assurance that shift supervisors perform their jobs safely and competently.

  18. 17 CFR 240.15b7-1 - Compliance with qualification requirements of self-regulatory organizations.

    Science.gov (United States)

    2010-04-01

    ... § 240.15b7-1 Compliance with qualification requirements of self-regulatory organizations. No registered... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Compliance with qualification requirements of self-regulatory organizations. 240.15b7-1 Section 240.15b7-1 Commodity and Securities Exchanges...

  19. 81 FR 1 - Pilot Certification and Qualification Requirements for Air Carrier Operations; Technical Amendment

    Science.gov (United States)

    2016-01-04

    ...The FAA is correcting a final rule published on July 15, 2013. In that rule, the FAA amended its regulations to create new certification and qualification requirements for pilots in air carrier operations. The FAA unintentionally required without notice and comment that if a certificate holder conducting part 135 operations who has voluntarily chosen and been authorized to comply with the part 121 training and qualification requirements, a pilot serving as a second in command in part 135 for that certificate holder is required to have an airline transport pilot certificate and an aircraft type rating. This document corrects those errors and makes several additional miscellaneous corrections to part 61 and a cross-reference error in part 121.

  20. Glass fabrication and analysis literature review and method selection for WTP waste feed qualification

    Energy Technology Data Exchange (ETDEWEB)

    Peeler, D. K. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2013-06-01

    The waste feed qualification program is being developed to protect the Hanford Tank Waste Treatment and Immobilization Plant (WTP) safety basis, technical basis, and design by assuring waste acceptance requirements are met for each staged waste feed Campaign prior to transfer from the Hanford Tank Farm to the WTP.

  1. Next Generation Nuclear Plant Materials Selection and Qualification Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    R. Doug Hamelin; G. O. Hayner

    2004-11-01

    The U.S. Department of Energy (DOE) has selected the Very High Temperature Reactor (VHTR) design for the Next Generation Nuclear Plant (NGNP) Project. The NGNP will demonstrate the use of nuclear power for electricity and hydrogen production without greenhouse gas emissions. The reactor design is a graphite-moderated, helium-cooled, prismatic or pebble bed thermal neutron spectrum reactor with an average reactor outlet temperature of at least 1000 C. The NGNP will use very high burn up, lowenriched uranium, TRISO-Coated fuel in a once-through fuel cycle. The design service life of the NGNP is 60 years.

  2. Qualification of Simulation Software for Safety Assessment of Sodium Cooled Fast Reactors. Requirements and Recommendations

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Nicholas R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Pointer, William David [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sieger, Matt [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Flanagan, George F. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moe, Wayne [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); HolbrookINL, Mark [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    The goal of this review is to enable application of codes or software packages for safety assessment of advanced sodium-cooled fast reactor (SFR) designs. To address near-term programmatic needs, the authors have focused on two objectives. First, the authors have focused on identification of requirements for software QA that must be satisfied to enable the application of software to future safety analyses. Second, the authors have collected best practices applied by other code development teams to minimize cost and time of initial code qualification activities and to recommend a path to the stated goal.

  3. An overview of fiber-to-the-premises (FTTP) product requirements and qualification programs

    Science.gov (United States)

    Gebizlioglu, Osman S.; Gallo, Ernest J.

    2006-04-01

    North American deployments of FTTP architectures have been rapidly increasing. While the FTTP market is being driven by major telecommunications service providers, equipment suppliers have been scrambling to bring products to market that will ensure them a piece of this high-stakes market. In this invited presentation/paper, we propose to examine the technical requirements that are needed to support the new FTTP network with a host of new products that have been in development. To enable service providers select the best new products for FTTP deployment, product selection needs to be based on the analysis and testing of new products for performance and reliability, Telcordia, in its traditional role of telecommunications standards development, has been publishing generic requirements (GR) documents that have been used by suppliers, service providers and the industry at large. Product qualification programs based on the established performance and reliability requirements/standards have been designed to evaluate products to determine if they can 1) withstand the rigors of the outside plant deployment environment and perform for extended periods of time, 2) be upgradeable, and 3) craft friendly. The outside plant is a tough environment to live in. A product must perform under the extreme conditions of cold down -40°C (-40°F) and hot up to 46°C (115°F) with high humidity of 95%, rain, snow, sleet, vibration due to traffic, lightning, heating due to solar loads, high winds, ice, sand storms, and products are even tested to demonstrate if they can continue to operate in an earthquake, a wild fire and a shotgun blast. All FTTP products are not only expected to perform, but they must meet stringent optical performance criteria of low insertion loss and reflectance / return loss at a broad range of wavelengths from 1310, 1490, 1550 and 1625 nm. While the upstream (from the customer to the CO) voice and data transmission is currently planned over 1310-nm wavelength, the

  4. Environmental qualification design for NPP refurbishment to comply with revised licensing requirements

    Energy Technology Data Exchange (ETDEWEB)

    MacBeth, M. J.; Hemmings, R. L. [Canatom-NPM, Ontario (Canada)

    2002-04-15

    Recent Canadian Nuclear Regulatory decisions have imposed Environmental Qualification (EQ) requirements for twenty-four Reactor Building (RB) airlocks at the four-unit Pickering Nuclear Generating Station-B (PNGS-B) facility. This paper describes the EQ modification design work completed by CANATOM-NPM for the problematic aspects for such projects. The airlocks allow RB access while providing a containment boundary and are designed to prevent a potential breach of containment for all analysed station conditions. Each PNGS-B unit has three large equipment airlocks and three smaller personnel airlocks. The airlocks must function under postulated worst-case design basis accident(DBA) conditions for assigned mission durations. The design must ensure that accident conditions cannot spuriously initiate an un-requested door opening. CANATOM-NPM reviewed site data to specify the necessary EQ modifications required to satisfy licensing requirements while providing a correct and complete as-found record of the existing airlock installation. The design team assessed the installed airlocks configuration against environmental qualification requirements to finalize the list of necessary modifications. A comprehensive, cross-discipline review of proposed design changes was completed to identify any further changes required to satisfy the final EQ licensing goal. The design team also conducted a design review of the EQ modification installation strategy to integrate the design deliverables with the installation team requirements while attempting to minimize necessary outage time for EQ modification installations. This project was completed on schedule and within the cost limitations required by the client with comprehensive, high quality final design packages. Overall improvements were realized for OPG system drawings and the electronic documentation of design data. The EQ modifications designed by CANATOM-NPM will ensure the continued operation of the PNGS-B NPP past December 31

  5. Joint helmet-mounted cueing system (JHMCS) helmet qualification testing requirements

    Science.gov (United States)

    Orf, Garry W.

    1998-08-01

    The Joint Helmet-Mounted Cueing System (JHMCS) program will provide capability to cue high off-boresight (HOBS) weapons to the operator's line of sight and to confirm weapon sensor LOS for the US Air Force and US Navy (USN) aircrew. This capability will ensure the USAF and USN pilots a first shot opportunity. The JHMCS incorporates an ejection-compatible helmet-mounted display system that will be installed on F- 15, F-16, F/A-18, and F-22 aircraft. The JHMCS includes a flight helmet with display optics, miniature cathode ray tube, magnetic receiver unit, miniature camera, automatic brightness control sensor, and microcontroller. The flight helmet for JHMCS is based on the new lightweight HGU-55A/P. This paper describes the requirements for the helmet qualification tests including: windblast, ejection tower, hanging harness, centrifuge, mass properties, energy attenuation and penetration resistance, noise attenuation, visor characteristics, compatibility demonstration, sled/in- flight ejection, water survival, standard conditions and environment. The test objective, success criteria, equipment configuration, and data collection requirements for each test is discussed.

  6. Adult Trainers in Greece: Qualifications, Teaching Effectiveness, and Competency-Based Selection

    Science.gov (United States)

    Brinia, Vasiliki; Kritikos, Dimitris

    2012-01-01

    The purpose of the research has been to investigate the views of adult education trainers with regards to the qualifications which form part of the "effective adult trainer profile." Trainers in Adult Education were asked to express their views on the specific qualifications (e.g. work experience, studies, etc.) which increase (and to…

  7. Entry qualifications and academic performance of architecture students in Nigerian Polytechnics: Are the admission requirements still relevant?

    Directory of Open Access Journals (Sweden)

    Peter O Adewale

    2014-03-01

    Full Text Available The competence of fresh graduates of architecture has been continuously criticized by the industry for inadequate knowledge. This is often blamed on the poor standard of education evidenced by poor performances in professional and degree/diploma examinations conducted by various schools of architecture in the country. Although, factors responsible for the scenario are well documented in the literature, most of these works are based on testimonial and circumstantial evidences relating to management of architectural education only. The aim of this paper is to investigate the relationship between entry qualifications and the performance of architecture students in Nigerian Polytechnics with a view to determining the relevance of current admission policy to architectural education in Nigeria. Data were obtained from official records in the Department of Architecture in four randomly selected polytechnics in the southwestern part of Nigeria. Pearson Product Moment Correlation (r was used to test the hypotheses. Findings reveal weak relationship between the two variables (physics and mathematics. This is contrary to the expectations of most scholars and policy makers who opine that students' proficiency in these subjects would enhance their performance at higher levels. The paper traces the contradiction to the poor handling of public examinations and misconception of architecture as being pure science. It holds that if these requirements are still relied upon for the admission of students into schools of architecture, wrong candidates would continue to gain entry into the profession. The paper concludes by recommending certain measures that are capable of reversing the trend.

  8. [Prospective qualification requirements in nursing care. Results and conclusions of the BMBF research network FreQueNz].

    Science.gov (United States)

    Schüler, G; Klaes, L; Rommel, A; Schröder, H; Köhler, T

    2013-08-01

    Demographic change, advances in medicine, and innovative health care services are leading to changes in the professional qualification requirements for nursing and care staff. Detecting future trends in relation to these requirements was the focus of a Delphi study developed as part of the BMBF FreQueNz initiative. After qualitative expert interviews, data collection was organized in three consecutive steps, with 243 interviews realized in the second wave. It was found that home care will further diversify in the fields of supporting and counseling services as well as in palliative care, resulting in the necessary expansion of specific qualifications (e.g., intensive care). Moreover, there will be an increased need for interprofessional, intersectoral, and intercultural coordination and communication skills. As a consequence of the delegation of medical tasks, new duties for nonmedical professions in inpatient and outpatient care will also arise. For instance, qualifications need to be tailored to the new demands of assessment, diagnostics, therapy, and patient education and they should take into account evidence-based knowledge as well as clinical practice guidelines. Consequently, the system of care professionals will further diversify through advanced training programs and the continued academization of nursing.

  9. 78 FR 45055 - Pilot Certification and Qualification Requirements for Air Carrier Operations

    Science.gov (United States)

    2013-07-26

    .... Nos. 61-130; 121-365; 135-127; 141-1; 142-9] RIN 2120-AJ67 Pilot Certification and Qualification... certificate with an appropriate appropriate aircraft type category and class rating; rating OR--An ATP (2) An instrument rating; and certificate with restricted privileges and an appropriate aircraft type rating; and (3...

  10. Water requirements of selected industries

    Science.gov (United States)

    ,; Mussey, Orville D.; Conklin, Howard L.; Durfor, Charles N.; Otts, Louis Ethelbert; Walling, Faulkner B.

    1955-01-01

    The early industries in America generally were established when and where demands for the products of industry arose. Most of the early industries were so located that their increasing requirements for transportation, raw materials, market, labor, and water supply could be satisfied economically. Many of these original plant locations have continued as modern industrial centers and their output has increased manyfold in meeting the demands of our growing Nation. The recent and current industrial expansion and the trend toward the growth of chemical industries, many Of which are heavy users of water, has resulted in a tremendous increase in the total withdrawal of water for industrial use as well as a large increase in the per capita use of water. This increase in industrial water requirement has strained the capacity of the developed water supplies in many areas, and in some instances the adequacy of the potential water supplies is questionable. The Geological Survey is engaged in preparing and publishing a series of reports describing the developed and undeveloped water resources of many important industrial areas. This work was started initially at the request of the National Securities Resources Board as a means to insure that water supplies are adequate for our rapidly expanding industrial development. Although many factors contribute to establishing the feasibility or even the limits of future industrial development, the one relating to available water supply is extremely important. A knowledge of the water requirements of various industries is valuable therefore in planning the logical development in any area where water supply is a critical factor. Thus far very little suitable information on the water requirements of our major industries is available for general planning. An inventory of unit water-use values in industry therefore would be generally helpful and also might tend to stimulate water-conservation methods. To obtain such information

  11. Qualification requirements and training programs for nonreactor nuclear facility personnel in the Operations Division of the Oak Ridge National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Preston, E.L.; Culbert, W.H.; Baldwin, M.E.; McCormack, K.E.; Rivera, A.L.; Setaro, J.A.

    1985-11-01

    This document describes the program for training, retraining, and qualification of nonreactor nuclear operators in the Operations Division of the Oak Ridge National Laboratory. The objective of the program is to provide the Operators and Supervisors of nuclear facilities the knowledge and skills needed to perform assigned duties in a safe and efficient manner and to comply with US Department of Energy Order 5480.1A Chapter V. This order requires DOE nuclear facilities to maintain formal training programs for their operating staff and documentation of that training.

  12. [Dementia Care Manager for patients with dementia. Determination of the requirements and qualifications contents for nurses in the DelpHi-MV study].

    Science.gov (United States)

    Dreier, A; Hoffmann, W

    2013-10-01

    Dementia is one of the most prevalent chronic progressive diseases in older age. The progression of dementia is associated with an increasing demand for patient care. Thus, the nursing profession fulfills important tasks in the supply of care in dementia. Care of dementia patients requires nurses with more specialized professional knowledge. Consequently, the development of new qualification concepts in dementia is needed. Therefore, the German Center for Neurodegenerative Diseases, Rostock/Greifswald, has developed a qualification according to the Dementia Care Management concept. A prospective cross-sectional study identified the tasks and qualifications of nurses as Dementia Care Managers. Overall, 27 tasks and 28 qualification items were identified for a nurse to qualify as a Dementia Care Manager. In the next step, the first version of the Dementia Care Management Curriculum was developed.

  13. 77 FR 37287 - Implementation of Statutory Amendments Requiring the Qualification of Manufacturers and Importers...

    Science.gov (United States)

    2012-06-21

    ... invoices and bills of lading in lieu of the recordkeeping requirements specified in Sec. Sec. 40.521(b) and... also be required to account for, and provide dates for, receipts of processed tobacco, use of processed... such receipts should be reflected in the required records and reports. The Altria Group also asked TTB...

  14. Risk-Informed Safety Margin Characterization Case Study: Selection of Electrical Equipment to Be Subjected to Environmental Qualification

    Energy Technology Data Exchange (ETDEWEB)

    D. P. Blanchard; R. W. Youngblood

    2014-06-01

    The Risk-Informed Safety Margin Characterization (RISMC) pathway of the DOE’s Light Water Reactor Sustainability (LWRS) program focuses on advancing the state of the art in safety analysis and risk assessment to support decision-making on nuclear power plant operation well beyond the originally designed lifetime of the plants (i.e., beyond 60 years). Among the issues being addressed in RISMC is the significance of SSC aging and how confident we are about our understanding of its impact on the margin between the loads SSCs are expected to see during normal operation and accident conditions, and the SSC capacities (their ability to resist those loads) as the SSCs age. In this paper, a summary is provided of a case study that examines SSC aging from an environmental qualification (EQ) perspective. The case study illustrates how the state of knowledge regarding SSC margin can be characterized given the overall integrated plant design, and was developed to demonstrate a method for deciding on which cables to focus, which cables are not so important from an environmental qualification margin standpoint, and what plant design features or operating characteristics determine the role that environmental qualification plays in establishing a safety case on which decisions regarding margin can be made. The selection of cables for which demonstration of margin with respect to aging and environmental challenges uses a technique known as Prevention Analysis. Prevention Analysis is a Boolean method for optimal selection of SSCs (that is, those combinations of SSCs both necessary and sufficient to meet a predetermined selection criterion) in a manner that allows demonstration that plant-level safety can be demonstrated by the collection of selected SSCs alone. Choosing the set of SSCs that is necessary and sufficient to satisfy the safety objectives, and demonstrating that the safety objectives can be met effectively, determines where resources are best allocated to assure SSC

  15. PEM-INST-001: Instructions for Plastic Encapsulated Microcircuit (PEM) Selection, Screening, and Qualification

    Science.gov (United States)

    Teverovsky, Alexander; Sahu, Kusum

    2003-01-01

    Potential users of plastic encapsulated microcircuits (PEMs) need to be reminded that unlike the military system of producing robust high-reliability microcircuits that are designed to perform acceptably in a variety of harsh environments, PEMs are primarily designed for use in benign environments where equipment is easily accessed for repair or replacement. The methods of analysis applied to military products to demonstrate high reliability cannot always be applied to PEMs. This makes it difficult for users to characterize PEMs for two reasons: 1. Due to the major differences in design and construction, the standard test practices used to ensure that military devices are robust and have high reliability often cannot be applied to PEMs that have a smaller operating temperature range and are typically more frail and susceptible to moisture absorption. In contrast, high-reliability military microcircuits usually utilize large, robust, high-temperature packages that are hermetically sealed. 2. Unlike the military high-reliability system, users of PEMs have little visibility into commercial manufacturers proprietary design, materials, die traceability, and production processes and procedures. There is no central authority that monitors PEM commercial product for quality, and there are no controls in place that can be imposed across all commercial manufacturers to provide confidence to high-reliability users that a common acceptable level of quality exists for all PEMs manufacturers. Consequently, there is no guaranteed control over the type of reliability that is built into commercial product, and there is no guarantee that different lots from the same manufacturer are equally acceptable. And regarding application, there is no guarantee that commercial products intended for use in benign environments will provide acceptable performance and reliability in harsh space environments. The qualification and screening processes contained in this document are intended to

  16. 26 CFR 1.992-3 - Deficiency distributions to meet qualification requirements.

    Science.gov (United States)

    2010-04-01

    ... requirements to be a DISC. Such designation shall be in the form of a communication sent at the time of such... subparagraph is an amount equal to the sum of its taxable income (if any) from each transaction giving rise to...

  17. Employers’ demand for qualifications and skills: increased merit selection in Austria, 1985-2005

    NARCIS (Netherlands)

    Dörfler, L.; van de Werfhorst, H.G.

    2009-01-01

    The paper attempts to empirically test skill demand on the Austrian labour market between 1985 and 2005 by making use of job advertisements. We analyze job advertisements covering a time span of 20 years. This allows us to examine whether there is a trend towards increased merit selection. Our

  18. Hybrid Qualifications

    DEFF Research Database (Denmark)

    has turned out as a major focus of European education and training policies and certainly is a crucial principle underlying the European Qualifications Framework (EQF). In this context, «hybrid qualifications» (HQ) may be seen as an interesting approach to tackle these challenges as they serve «two...... masters», i.e. by producing skills for the labour market and enabling individuals to progress more or less directly to higher education. The specific focus of this book is placed on conditions, structures and processes which help to combine VET with qualifications leading into higher education......Against the background of increasing qualification needs there is a growing awareness of the challenge to widen participation in processes of skill formation and competence development. At the same time, the issue of permeability between vocational education and training (VET) and general education...

  19. Spatial Qualification Tests for Highly Selective Compact Micromachined Band Pass Planar Filters

    Directory of Open Access Journals (Sweden)

    Raghida Hajj

    2012-01-01

    Full Text Available A highly selective planar band pass filter is proposed for satellite receivers to suppress intermodulation components. The 4-pole filter has a center frequency of 19.825 GHz with a bandwidth of 240 MHz. The measured quality factor is over 600 and the insertion losses are 4.1 dB. The micromachining technological process is used to fabricate this filter. A BCB (benzocyclobutene thin layer is used as an electrical and mechanical support for the filter. The compatibility of the BCB with the spatial constraints was tested. Various tests were accomplished for this purpose and the results of all these tests are presented in the paper. The tests showed a very small influence of the temperature variation and high temperature storage test and practically no influence of the radiation test on the circuit.

  20. Qualifications Mismatch and Skills Mismatch

    Science.gov (United States)

    Sutherland, John

    2012-01-01

    Purpose: The purpose of this paper is to estimate the extent of "over-qualification" (i.e. holding a qualification which is above that required to gain entry to the job being done) and "skills under-utilisation" (i.e. being in a job which does not make use of the knowledge and skills possessed) in the United Kingdom and to…

  1. Proposal for an extension to the procedure for the qualification and selection of network operators for the provision of outgoing fixed-line telephone calls

    CERN Document Server

    2004-01-01

    This document concerns a proposal for a three-year extension to the procedure for the qualification and selection of network operators for the provision of outgoing fixed-line telephone calls. The Finance Committee is invited to agree to the continuation of the procedure approved by the Finance Committee (CERN/FC/4407) for the selection of network operators for the provision of outgoing fixed-line telephone calls for a three-year period within an annual ceiling of 800 000 Swiss francs, bringing the total amount for the period to a maximum of 2 400 000 Swiss francs.

  2. 5 CFR 302.403 - Qualifications for promotion.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Qualifications for promotion. 302.403... EMPLOYMENT IN THE EXCEPTED SERVICE Selection and Appointment; Reappointment; and Qualifications for Promotion § 302.403 Qualifications for promotion. In determining qualifications for promotion with respect to an...

  3. Reaction Qualifications Revisited

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    2009-01-01

    of merit. Specifically, it preserves symmetry between negative evaluations of antimeritocratic bases of selection and negative evaluations of qualifications rooted in comparable antimeritocratic reactions. So if employers should not select among applicants on the basis of their (the employers') racial...... preferences, recipients should not respond to the applicant actually hired on the basis of their (the recipients') racial preferences. My account decomposes the meritocratic ideal into four separate norms, one of which applies to recipients rather than to selectors. Finally, it defends the view that reaction...... reaction-qualifications are entirely irrelevant from the point of view of merit, the view expounded here implies that the ideal of meritocracy and the norm of non-discrimination are less closely tied than theorists like Andrew Mason and David Miller believe.  ...

  4. 25 CFR 38.5 - Qualifications for educators.

    Science.gov (United States)

    2010-04-01

    ... for educators. (a) Qualifications related to positions. Job qualification requirements shall be at... State in which the position is located. (b) Qualifications related to individuals. An applicant for an education position must establish that he/she meets the requirements of the position by submitting an...

  5. RERTR Fuel Developmemt and Qualification Plan

    Energy Technology Data Exchange (ETDEWEB)

    Dan Wachs

    2007-01-01

    In late 2003 it became evident that U-Mo aluminum fuels under development exhibited significant fuel performance problems under the irradiation conditions required for conversion of most high-powered research reactors. Solutions to the fuel performance issue have been proposed and show promise in early testing. Based on these results, a Reduced Enrichment Research and Test Reactor (RERTR) program strategy has been mapped to allow generic fuel qualification to occur prior to the end of FY10 and reactor conversion to occur prior to the end of FY14. This strategy utilizes a diversity of technologies, test conditions, and test types. Scoping studies using miniature fuel plates will be completed in the time frame of 2006-2008. Irradiation of larger specimens will occur in the Advanced Test Reactor (ATR) in the United States, the Belgian Reactor-2 (BR2) reactor in Belgium, and in the OSIRIS reactor in France in 2006-2009. These scoping irradiation tests provide a large amount of data on the performance of advanced fuel types under irradiation and allow the down selection of technology for larger scale testing during the final stages of fuel qualification. In conjunction with irradiation testing, fabrication processes must be developed and made available to commercial fabricators. The commercial fabrication infrastructure must also be upgraded to ensure a reliable low enriched uranium (LEU) fuel supply. Final qualification of fuels will occur in two phases. Phase I will obtain generic approval for use of dispersion fuels with density less than 8.5 g-U/cm3. In order to obtain this approval, a larger scale demonstration of fuel performance and fabrication technology will be necessary. Several Materials Test Reactor (MTR) plate-type fuel assemblies will be irradiated in both the High Flux Reactor (HFR) and the ATR (other options include the BR2 and Russian Research Reactor, Dmitrovgrad, Russia [MIR] reactors) in 2008-2009. Following postirradiation examination, a report

  6. Home health agency preferences for staff nurse qualifications, and practices in hiring and orientation.

    Science.gov (United States)

    Kalnins, I

    1989-06-01

    The purpose of this study was to describe home health agency preferences with respect to staff nurse qualifications, and practices in hiring and orienting new staff. An 85-item home health staff nurse selection and orientation questionnaire was used to collect data from a random sample of 287 midwestern home health agencies in 12 states. Qualifications rated most highly were medical-surgical experience, venipuncture skills, completion of a physical assessment course, intravenous therapy skills, and patient-teaching skills. With agency sponsorship (traditional, proprietary, and hospital-based) as the independent variable, the three types of agencies were significantly different on ratings of six qualifications and six orientation topics. None of the agencies rated a BSN degree as very important or required, and the same was true for completion of a student experience in community health nursing. Preference for qualifications in this study is consistent with increasing acuteness of patients' illness and technologic complexity of home care.

  7. Bhutan's First Library Qualification, Background and Development

    Science.gov (United States)

    Ransom, Sylvia

    2011-01-01

    During a six month contract with the Royal University of Bhutan, the author was required to develop the initial stages of a first library qualification to be offered in Bhutan. Questions raised by this project included: is a first qualification in librarianship needed in Bhutan? What are the potential student numbers in such a programme? What…

  8. 14 CFR 121.453 - Flight engineer qualifications.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Flight engineer qualifications. 121.453... REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Crewmember Qualifications § 121.453 Flight engineer qualifications. (a) No certificate holder may use any person nor may any person serve as a flight engineer on an...

  9. 40 CFR 205.57 - Selective enforcement auditing requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Selective enforcement auditing requirements. 205.57 Section 205.57 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57...

  10. Requirements for selection of conventional and innate T lymphocyte lineages

    Science.gov (United States)

    Horai, Reiko; Mueller, Kristen L.; Handon, Robin A.; Cannons, Jennifer L.; Anderson, Stacie M.; Kirby, Martha R.; Schwartzberg, Pamela L.

    2008-01-01

    Summary Mice deficient in the Tec kinase Itk develop a large population of CD8 cells with properties resembling NKT and other innate T cell lineages, including expression of memory markers, rapid production of cytokines and dependence on IL-15. Like NKT cells, these CD8 cells can be selected on hematopoietic cells. We demonstrate here that these CD8 cell phenotypes result from selection on hematopoietic cells—forcing selection on the thymic stroma reduces the number and innate cell phenotypes of mature CD8 SP cells associated with Itk-deficiency. We further demonstrate that, similar to NKT cells, selection of innate-type CD8 cells in Itk-deficient mice strictly requires the adaptor molecule SAP, whereas, acquisition of the innate characteristics requires CD28. Our results suggest that SAP and Itk reciprocally regulate selection of innate and conventional CD8 cells on hematopoietic cells and the thymic epithelium, respectively, whereas CD28 regulates development of innate phenotypes resulting from selection on hematopoietic cells. PMID:18031697

  11. The Concept of Qualification Assessment

    Directory of Open Access Journals (Sweden)

    V. I. Blinov

    2012-01-01

    Full Text Available The necessity of changing the approach to qualification assessment appears to be one of the main topics for discussion in the modern scientific pedagogic society. In the sphere of vocational education both in Russia and abroad, the emphasis is increasingly shifting to the learning outcomes: the expediency principle is regarded as the leading one; the operational component of professional readiness takes the first place; the results of mastering the educational program, as well as self-education and self- development, are viewed as providing the qualification significant for the labor market and based on the actual work requirements.Unfortunately, there is no unified methodology of qualification assessment; such integrated assessment of professional readiness for applying the acquired knowledge and skills in practice is urgently needed. The authors recommend a new concept of qualification assessment based on the experience of higher vocational educational establishments both in Russia and abroad. The reasons for changing the content of qualification concept are out- lined, the principles of quality assessment in modern conditions are revealed along with the concept terminology mechanism and method of independent expertise procedure. 

  12. SATISFACTION OF QUALIFICATION REQUIREMENTS OF EMPLOYERS APPLIED TO SOFTWARE ENGINEERS IN THE PROCESS OF TRAINING AT HIGHER EDUCATIONAL INSTITUTIONS

    Directory of Open Access Journals (Sweden)

    Vladislav Kruhlyk

    2017-03-01

    Full Text Available In the article, based on the analysis of the problems of the professional training of software engineers in higher educational institutions, was shown that the contents of the curricula for the training of software engineers in basic IT specialties in higher education institutions generally meet the requirements to them at the labor market. It is stated that at the present time there are certain changes in the job market not only in the increasing demand for IT professionals but also in the requirements settled for future specialists. To scientists’ opinion, at present there is a gap between the level of expectation of employers and the level of education of graduates of IT-specialties of universities. Due to the extremely fast pace of IT development, already at the end of the studies, students' knowledge may become obsolete. We are talking about a complex of competencies offered by university during training of specialist for their relevance and competitiveness at the labor market. At the same time, the practical training of students does not fully correspond to the current state of information technology. Therefore, it is necessary to ensure the updating of the contents of the academic disciplines with the aim of providing quality training of specialists.

  13. Qualification Testing of Engineering Camera and Platinum Resistance Thermometer (PRT) Sensors for Mars Science Laboratory (MSL) Project under Extreme Temperatures to Assess Reliability and to Enhance Mission Assurance

    Science.gov (United States)

    Ramesham, Rajeshuni; Maki, Justin N.; Cucullu, Gordon C.

    2008-01-01

    Package Qualification and Verification (PQV) of advanced electronic packaging and interconnect technologies and various other types of qualification hardware for the Mars Exploration Rover/Mars Science Laboratory flight projects has been performed to enhance the mission assurance. The qualification of hardware (Engineering Camera and Platinum Resistance Thermometer, PRT) under extreme cold temperatures has been performed with reference to various project requirements. The flight-like packages, sensors, and subassemblies have been selected for the study to survive three times (3x) the total number of expected temperature cycles resulting from all environmental and operational exposures occurring over the life of the flight hardware including all relevant manufacturing, ground operations and mission phases. Qualification has been performed by subjecting above flight-like qual hardware to the environmental temperature extremes and assessing any structural failures or degradation in electrical performance due to either overstress or thermal cycle fatigue. Experiments of flight like hardware qualification test results have been described in this paper.

  14. Bruel & Kjær Solutions for Satellite Qualification Testing

    Science.gov (United States)

    Wethly, Patrick

    2012-07-01

    Early 2011 the Laboratório de Integração e Testes (LIT) do Instituto Nacional de Pesquisas Espaciais (INPE, http://www.lit.inpe.br/) in Brazil selected Brüel & Kjær as supplier to replace their existing data acquisition and vibration test system for satellite qualification testing. The Brüel & Kjær supplied Satellite Qualification Test System (SQTS) is an integrated total solution for vibration, shock and acoustic fatigue satellite testing. Based on Brüel & Kjær state-of-the-art data acquisition platform LAN-XI the delivered solution integrates different Brüel & Kjær software applications providing a fully integrated solution supporting INPE’s workflow requirements for Satellite Qualification testing. The delivered solutions allows the INPE engineers to seamlessly run the different tasks at hand ensuring ease of use for setup, data acquisition & post processing in relation to the typical satellite qualification tests and is designed to allow multiple INPE engineers and INPE’s client to validate and witness data acquisition in real- time. This paper describes the integrated solutions provided to INPE.

  15. A simulation of optimum power requirements of selected grain threshers

    Directory of Open Access Journals (Sweden)

    V. I. O. Ndirika

    2001-10-01

    Full Text Available A power requirement model was simulated at three factor interaction of process variables in order to select a combination of optimum crop and machine variables (crop moisture content, feed rate, cylinder speed that will yield minimum grain losses for millet and sorghum threshers. The viability of the model was demonstrated in selecting minimum grain loss for various combinations of process variables and power requirement. Result obtained from the simulations revealed that a minimum grain loss of 0.09% was obtained for millet thresher and 0.35% for the sorghum thresher at 9% grain moisture content, 5m/s cylinder speed, and feed rate of 0.03 kg/s. The power requirements obtained at these levels were 2.5kW and 4.6kW for millet and sorghum threshers respectively. This compares well with actual measurements using the same values of the parameters with a minimum grain loss of 0.10% for millet and 0.46% for sorghum threshers, at 2.45kW and 4.5kW power requirements for millet and sorghum threshers respectively

  16. TOUGH2 software qualification

    Energy Technology Data Exchange (ETDEWEB)

    Pruess, K.; Simmons, A.; Wu, Y.S.; Moridis, G.

    1996-02-01

    TOUGH2 is a numerical simulation code for multi-dimensional coupled fluid and heat flow of multiphase, multicomponent fluid mixtures in porous and fractured media. It belongs to the MULKOM ({open_quotes}MULti-KOMponent{close_quotes}) family of codes and is a more general version of the TOUGH simulator. The MULKOM family of codes was originally developed with a focus on geothermal reservoir simulation. They are suited to modeling systems which contain different fluid mixtures, with applications to flow problems arising in the context of high-level nuclear waste isolation, oil and gas recovery and storage, and groundwater resource protection. TOUGH2 is essentially a subset of MULKOM, consisting of a selection of the better tested and documented MULKOM program modules. The purpose of this package of reports is to provide all software baseline documents necessary for the software qualification of TOUGH2.

  17. Power system requirements and selection for the space exploration initiative

    Energy Technology Data Exchange (ETDEWEB)

    Biringer, K.L. (Sandia National Labs., Albuquerque, NM (United States)); Bartine, D.E. (Oak Ridge National Lab., TN (United States)); Buden, D. (Idaho National Engineering Lab., Idaho Falls, ID (United States)); Foreman, J. (Naval Research Lab., Washington, DC (United States)); Harrison, S. (Strategic Defense Initiative Organization, Washington, DC (United States))

    1991-01-01

    The Space Exploration Initiative (SEI) seeks to reestablish a US program of manned and unmanned space exploration. The President has called for a program which includes a space station element, a manned habitation of the moon, and a human exploration of Mars. The NASA Synthesis Group has developed four significantly different architectures for the SEI program. One key element of a space exploration effort is the power required to support the missions. The Power Speciality Team of the Synthesis Group was tasked with assessing and evaluating the power requirements and candidate power technologies for such missions. Inputs to the effort came from existing NASA studies as well as other governments agency inputs such as those from DOD and DOE. In addition, there were industry and university briefings and results of solicitations from the AIAA and the general public as part of the NASA outreach effort. Because of the variety of power needs in the SEI program, there will be a need for multiple power system technologies including solar, nuclear and electrochemical. Due to the high rocket masses required to propel payloads to the moon and beyond to Mars, there is great emphasis placed on the need for high power density and high energy density systems. Power system technology development work is needed results will determine the ultimate technology selections. 23 refs., 10 figs.

  18. Preclinical biomarker qualification.

    Science.gov (United States)

    Sauer, John-Michael; Porter, Amy C

    2017-01-01

    Biomarkers are ubiquitously used within drug development programs in both nonclinical species and in humans to assess safety and efficacy of novel compounds. To routinely apply such novel biomarkers with certainty, a well-defined data package is necessary for review and endorsement by regulatory agencies including the US Food and Drug Administration, European Medicines Agency, and Japanese Pharmaceuticals and Medical Devices Agency. This type of endorsement is known as regulatory qualification. Novel approaches are being applied to speed the process, lower the resource intensity, and increase the accessibility of biomarker qualification data and it is likely that consortia will continue to play a fundamental role in the qualification process by bringing together like-minded stakeholders focused on specific tools to accelerate drug development. This article will focus on learnings from the previous three nonclinical biomarker qualification projects, as well as discuss the progression of preclinical biomarker projects into the clinical qualification space and the current strategy for the use of nonclinical biomarker data in the translational qualification of clinical biomarkers; much like nonclinical information is used in the approval of drug development candidates. Impact statement This minireview provides an overview of the history of preclinical biomarker qualification by summarizing the three examples of this type of qualification with US Food and Drug Administration, European Medicines Agency, and Japanese Pharmaceuticals and Medical Devices Agency. In addition, an overview of the biomarker qualification process is included to educate key stakeholders with links to relevant white papers that provide information on current evidentiary considerations. The manuscript also provides new information on the evolution of the role that preclinical qualification plays in clinical qualification of biomarkers and the novel approaches that are being utilized to improve the

  19. Scientific requirements and frequency selection for SMILES-2 proposal

    Science.gov (United States)

    Manago, Naohiro; Suzuki, Makoto; Ozeki, Hiroyuki

    Superconducting Submillimeter-Wave Limb-emission Sounder (SMILES) was the first instrument to use 4K cooled SIS (Superconductor-Insulator-Superconductor) detection system for the observation of the atmosphere in the frequency regions 625 GHz (Bands A and B) and 650 GHz (Band C). It has demonstrated its high sensitivity (System Temperature, Tsys, 250 K) for measuring stratospheric and mesospheric species, O _{3}, HCl, ClO, HO _{2}, HOCl, BrO, and O _{3} isotopes from Oct. 12, 2009 to Apr. 21, 2010. Since SMILES operation has terminated after only 6 months operation due to failure of sub-mm local oscillator (and later 4K cooler system), there exist strong scientific demand to develop successor of SMILES, the SMILES-2, which has optimized and enhanced frequency coverage to observe: (a) BrO and HOCl without interferences of stronger emission lines, (b) N _{2}O, H _{2}O, NO _{2}, and CH _{3}Cl not covered by the SMILES frequency regions, and (c) O _{2} line to measure temperature. This paper discusses possible SMILES-2 band selection considering limited instrument resources (number of SIS mixers and sub-mm local oscillator) and scientific requirements. Temperature can be observed by using O _{2} emission lines. We selected 487.249 GHz, which is highest frequency below SMILES 600 GHz observation, O _{2} line to obtain highest vertical IFOV. There is H _{2}O line at 488.1 GHz. Two spectrometers (FFT spectrometer), one with 4 GHz bandwidth and 1 MHz resolution for retrieval of temperature and other species, and the other with high frequency resolution (60 km) and line of sight wind velocity (2 m/s precision). In the case of 4K cooling, temperature can be retrieved within 2% up to 100 km. In summary, current SMILES-2 scientific requirements can be achieved by having sub-mm frequency bands listed in Table 1, (1) 487±2 GHz (O _{2}, H _{2}O), (2) 527±2 GHz (BrO, NO _{2}, H _{2}CO, N _{2}O, HO _{2}, etc), (3) 614±2 GHz (HOCl), (4) 626±2 GHz (SMILES Bands A+B), (5) 637±2

  20. 48 CFR 6301.2 - Qualifications of members.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Qualifications of members... CONTRACT APPEALS BOARD OF CONTRACT APPEALS 6301.2 Qualifications of members. Each member of the Board must... District of Columbia. Members of the Board are selected and appointed to serve in the same manner as...

  1. Requirements for selection of conventional and innate T lymphocyte lineages

    OpenAIRE

    Horai, Reiko; Mueller, Kristen L.; Handon, Robin A.; Cannons, Jennifer L.; Anderson, Stacie M.; Kirby, Martha R.; Schwartzberg, Pamela L.

    2007-01-01

    Mice deficient in the Tec kinase Itk develop a large population of CD8 cells with properties resembling NKT and other innate T cell lineages, including expression of memory markers, rapid production of cytokines and dependence on IL-15. Like NKT cells, these CD8 cells can be selected on hematopoietic cells. We demonstrate here that these CD8 cell phenotypes result from selection on hematopoietic cells—forcing selection on the thymic stroma reduces the number and innate cell phenotypes of matu...

  2. 12 CFR 563c.3 - Qualification of public accountant.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Qualification of public accountant. 563c.3... REQUIREMENTS Form and Content of Financial Statements § 563c.3 Qualification of public accountant. (See also 17 CFR 210.2-01.) The term “qualified public accountant” means a certified public accountant or licensed...

  3. Unintended Consequences: How Qualification Constrains Innovation

    Science.gov (United States)

    Brice, Craig A.

    2011-01-01

    The development and implementation of new materials and manufacturing processes for aerospace application is often hindered by the high cost and long time span associated with current qualification procedures. The data requirements necessary for material and process qualification are extensive and often require millions of dollars and multiple years to complete. Furthermore, these qualification data can become obsolete for even minor changes to the processing route. This burden is a serious impediment to the pursuit of revolutionary new materials and more affordable processing methods for air vehicle structures. The application of integrated computational materials engineering methods to this problem can help to reduce the barriers to rapid insertion of new materials and processes. By establishing predictive capability for the development of microstructural features in relation to processing and relating this to critical property characteristics, a streamlined approach to qualification is possible. This paper critically examines the advantages and challenges to a modeling-assisted qualification approach for aerospace structural materials. An example of how this approach might apply towards the emerging field of additive manufacturing is discussed in detail.

  4. 49 CFR 180.409 - Minimum qualifications for inspectors and testers.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Minimum qualifications for inspectors and testers... Minimum qualifications for inspectors and testers. (a) Except as otherwise provided in this section, any... employer retains a copy of the tester's qualifications with the documents required by § 180.417(b). [Amdt...

  5. 14 CFR 60.16 - Additional qualifications for a currently qualified FSTD.

    Science.gov (United States)

    2010-01-01

    ... TRANSPORTATION (CONTINUED) AIRMEN FLIGHT SIMULATION TRAINING DEVICE INITIAL AND CONTINUING QUALIFICATION AND USE... training, evaluation, or flight experience requirements of this chapter beyond the qualification issued for... issues an amended Statement of Qualification in accordance with § 60.15(h). (d) The sponsor may not...

  6. Relationship Between Teachers\\' Qualification And Students ...

    African Journals Online (AJOL)

    It has been observed that students\\' performance in technical subjects is very poor. Coupled with this problem is that of lack of qualified technical teachers. This study determines the relationship between teachers\\' qualification and students\\' performance in technical subjects in selected schools in northern Nigeria.

  7. Design based binning for litho qualification and process window qualification

    Science.gov (United States)

    Fischer, Andreas; Seifert, Uwe; Wehner, Arno; Karsenti, Laurent; Geshel, Mark; Conley, Amiad; Gscheidlen, Dieter; Bartov, Avishai

    2008-03-01

    It is well known that as design rule shrink advanced techniques are required in-order to precisely and controllably print the design intent on a wafer. The commonly used techniques to overcome the resolution limit are OPC and RET. The goal of these techniques is to compensate for an expected local interaction between the light, mask pattern and photoresist, which will otherwise result in a mismatch between the printed pattern and design intent and lead to fatal yield failures. It is this interaction which dominates the extensive time-consuming mask qualification fabs are required to perform before a new mask on a new product can be inserted into a production line. In this paper, a new approach and Litho Qualification Monitor (LQM) system, implemented in Qimonda Dresden fab, for ultra fast pattern failure classification based on design information (Design Based Binning), coupled with an automatic interface to SEM metrology tool will be presented. The system centralizes all the operations required for the identification and analysis of marginally-printed systematic structures.

  8. An Evaluation of the Major Qualifications Desired of Air Force System Program Managers

    Science.gov (United States)

    1975-01-01

    trait qualifications desired of system program managers over the program life cycle. Interviews were conduqted with the present system program managers of...structure, program managers E.re identified as symbols of leadership of their programs (5:86). 13 The Deputy Secretary of Defense issued a memo- randum...experience, and managerial trait requirements irto the selection and training process of program managers . It is hoped that this research effort will

  9. Synapsin Is Selectively Required for Anesthesia-Sensitive Memory

    Science.gov (United States)

    Knapek, Stephan; Gerber, Bertram; Tanimoto, Hiromu

    2010-01-01

    Odor-shock memory in "Drosophila melanogaster" consists of heterogeneous components each with different dynamics. We report that a null mutant for the evolutionarily conserved synaptic protein Synapsin entails a memory deficit selectively in early memory, leaving later memory as well as sensory motor function unaffected. Notably, a consolidated…

  10. Qualification of a Voltammetry Measurement System

    OpenAIRE

    Scholz, Sunna

    2014-01-01

    The voltammetry measurement system consisting of a potentiostat μStat 200, electrode strips and accessories has been scrutinized, following the four phases of instrument qualification. These are design qualification, installation qualification, operational qualification and performance qualification in succeeding order. As design qualification operational specifications of the voltammetry measurement system have been collected. These were the innovative technique of screen printing electro...

  11. Development of the material selection practice - a study exploring articulation of material requirements

    DEFF Research Database (Denmark)

    Lenau, Torben Anker; Hasling, Karen Marie

    2014-01-01

    This paper explores how the material selection matrix is used in a materials and sustainability course. The matrix encourages the students to articulate material selection requirements to become more competent in exploring new materials and selecting materials for a given design task. The study i...... students to use a fixed number of technical, experiential and sustainability oriented requirements....

  12. The trophic requirements of selected underwood species occurring in forests

    OpenAIRE

    Lasota Jarosław; Błońska Ewa; Wanic Tomasz; Zwydak Maciej

    2014-01-01

    The subject of this study were soil requirements of common woody shrubs, which may be part of the forest understory (Sorbus aucuparia L., Frangula alnus Mill., Corylus avellana L., Juniperus communis L., Padus avium Mill., Euonymus europaea L., Sambucus nigra L.). We focused on phytocenoses in the vicinity of natural forests in reserves and national parks of Polish lowlands and defined optimal types and subtypes of soil with trophic variations for each underwood species. The range of trophis...

  13. Establishment of coral-algal symbiosis requires attraction and selection.

    Directory of Open Access Journals (Sweden)

    Hiroshi Yamashita

    Full Text Available Coral reef ecosystems are based on coral-zooxanthellae symbiosis. During the initiation of symbiosis, majority of corals acquire their own zooxanthellae (specifically from the dinoflagellate genus Symbiodinium from surrounding environments. The mechanisms underlying the initial establishment of symbiosis have attracted much interest, and numerous field and laboratory experiments have been conducted to elucidate this establishment. However, it is still unclear whether the host corals selectively or randomly acquire their symbionts from surrounding environments. To address this issue, we initially compared genetic compositions of Symbiodinium within naturally settled about 2-week-old Acropora coral juveniles (recruits and those in the adjacent seawater as the potential symbiont source. We then performed infection tests using several types of Symbiodinium culture strains and apo-symbiotic (does not have Symbiodinium cells yet Acropora coral larvae. Our field observations indicated apparent preference toward specific Symbiodinium genotypes (A1 and D1-4 within the recruits, despite a rich abundance of other Symbiodinium in the environmental population pool. Laboratory experiments were in accordance with this field observation: Symbiodinium strains of type A1 and D1-4 showed higher infection rates for Acropora larvae than other genotype strains, even when supplied at lower cell densities. Subsequent attraction tests revealed that three Symbiodinium strains were attracted toward Acropora larvae, and within them, only A1 and D1-4 strains were acquired by the larvae. Another three strains did not intrinsically approach to the larvae. These findings suggest the initial establishment of corals-Symbiodinium symbiosis is not random, and the infection mechanism appeared to comprise two steps: initial attraction step and subsequent selective uptake by the coral.

  14. 75 FR 28684 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-05-21

    ... established medical history or clinical diagnosis of diabetes mellitus currently requiring insulin for control... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... prohibiting persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles...

  15. 75 FR 8182 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-02-23

    ... person has no established medical history or clinical diagnosis of diabetes mellitus currently requiring... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in...

  16. 78 FR 24795 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-26

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce...

  17. 77 FR 74271 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-12-13

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  18. 77 FR 63411 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-10-16

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  19. 78 FR 50486 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-08-19

    ... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  20. 77 FR 48587 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-08-14

    ... for exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  1. 78 FR 79062 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-27

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  2. 78 FR 26419 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-05-06

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  3. 78 FR 20381 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-04

    ... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  4. 78 FR 1927 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  5. 78 FR 1923 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  6. Qualification of Engineering Camera for Long-Duration Deep Space Missions

    Science.gov (United States)

    Ramesham, Rajeshuni; Maki, Justin N.; Pourangi, Ali M.; Lee, Steven W.

    2012-01-01

    Qualification and verification of advanced electronic packaging and interconnect technologies, and various other types of hardware elements for the Mars Exploration Rover s Spirit and Opportunity (MER)/Mars Science Laboratory (MSL) flight projects, has been performed to enhance the mission assurance. The qualification of hardware (engineering camera) under extreme cold temperatures has been performed with reference to various Mars-related project requirements. The flight-like packages, sensors, and subassemblies have been selected for the study to survive three times the total number of expected diurnal temperature cycles resulting from all environmental and operational exposures occurring over the life of the flight hardware, including all relevant manufacturing, ground operations, and mission phases. Qualification has been performed by subjecting above flight-like hardware to the environmental temperature extremes, and assessing any structural failures or degradation in electrical performance due to either overstress or thermal cycle fatigue. Engineering camera packaging designs, charge-coupled devices (CCDs), and temperature sensors were successfully qualified for MER and MSL per JPL design principles. Package failures were observed during qualification processes and the package redesigns were then made to enhance the reliability and subsequent mission assurance. These results show the technology certainly is promising for MSL, and especially for longterm extreme temperature missions to the extreme temperature conditions. The engineering camera has been completely qualified for the MSL project, with the proven ability to survive on Mars for 2010 sols, or 670 sols times three. Finally, the camera continued to be functional, even after 2010 thermal cycles.

  7. Nitrogen requirements of cassava in selected soils of Thailand

    Directory of Open Access Journals (Sweden)

    Jakchaiwat Kaweewong

    2013-08-01

    Full Text Available Cassava (Manihot esculenta is one of the most important export crops in Thailand, yet the nitrogen requirement is unknown and not considered by growers and producers. Cassava requirements for N were determined in field experiments during a period of four years and four sites on the Satuk (Suk, Don Chedi (Dc, Pak Chong (Pc,and Ban Beung (BBg soil series in Lopburi, Supanburi, Nakhon Ratchasima, and Chonburi sites, respectively. The fertilizer treatment structure comprised 0, 62.5, 125, 187.5, 250 and 312.5 kg N ha^(-1 as urea. At each site cassava was harvested at nine months and yield parameters and the minimum datasets were taken. The fertilizer rate which resulted in maximum yield ranged from 187.5 kg N ha^(-1 in Supanburi and Chonburi (fresh weight yield of 47,500 and 30,000 kg ha^(-1 respectively to 250 kg N ha^(-1 in Lopburi and Nakhon Ratchasima (fresh weight yield of 64,100 and 46,700 kg ha^(-1 respectively. Yield appeared to decrease at the higher, 312 kg ha^(-1, at Supanburi and Lopburi, and 250 kg ha^(-1 (Chonburi fertilizer N rates. Net revenue was 70.4 and 72.9 % higher than where no N was appliedLopburi and Nakhon Ratchasima sites. Net revenue at the Supanburi and Chonburi sites were 53.8 and 211.0 % higher than that where no N was applied. This study suggests that at all sites improved cassava production and net revenue could be obtained with the judicious application of higher quantities of N. The results provide needed guidance to nitrogen fertilization of the important industrial crop cassava in Thailand.

  8. Qualification of a select one-stage activated partial thromboplastin time-based clotting assay and two chromogenic assays for the post-administration monitoring of nonacog beta pegol.

    Science.gov (United States)

    Tiefenbacher, S; Bohra, R; Amiral, J; Bowyer, A; Kitchen, S; Lochu, A; Rosén, S; Ezban, M

    2017-10-01

    Essentials Nonacog beta pegol (N9-GP) is an extended half-life, recombinant human factor IX (FIX). One-stage clotting (OSC) and chromogenic FIX activity assays were assessed for N9-GP recovery. OSC STA(®) -Cephascreen(®) , ROX FIX and BIOPHEN FIX chromogenic assays were qualified for N9-GP. Other extended half-life factor products should be assessed in a similar way prior to approval. Background Nonacog beta pegol (N9-GP) is an extended half-life, glycoPEGylated recombinant human factor IX that is under development for the prophylaxis and treatment of bleeding episodes in hemophilia B patients. Considerable reagent-dependent variability has been observed when one-stage clotting assays are used to measure the recovery of recombinant FIX products, including N9-GP. Objective To qualify select one-stage clotting and chromogenic FIX activity assays for measuring N9-GP recovery. Methods The accuracy and precision of the one-stage clotting assay (with the STA-Cephascreen activated partial thromboplastin [APTT] reagent) and the ROX Factor IX and BIOPHEN Factor IX chromogenic assays for measuring N9-GP recovery were assessed in N9-GP-spiked hemophilia B plasma samples in a systematic manner at three independent sites, with manufacturer-recommended protocols and/or site-specific assay setups, including different instruments. Results For each of the three FIX activity assays qualified on five different reagent-instrument systems, acceptable intra-assay and interassay accuracy and precision, dilution integrity, reagent robustness and freeze-thaw and short-term sample stabilities were demonstrated. The STA-Cephascreen assay showed a limited reportable range at one of the three qualification sites, and the BIOPHEN Factor IX assay showed suspect low-end sensitivity at one of the three qualification sites. An individual laboratory would account for these limitations by adjusting the assay's reportable range; thus, these findings are not considered to impact the respective

  9. Integrated Information System for Higher Education Qualifications

    Directory of Open Access Journals (Sweden)

    Catalin Ionut SILVESTRU

    2012-10-01

    Full Text Available In the present article we aim to study thoroughly and detail aspects related to architectures specific for e-learning and management of human resources training interconnected to management of qualifications. In addition, we take into consideration combining e-learning architectures with software in an e-learning system interconnected with the National Registry of Qualifications of Higher Education, in view of developing and information system that correlates educational supply from higher education from Romania with labor market demands through qualifications. The scientific endeavor consists of original architectural solutions to integrate data, systems, processes, services from various sources and to use them in the proposed system. The practical result of the scientific endeavor is represented by design of architectures required for developing an e-learning system interconnected with the National Registry of Qualifications from Romania, which involve in first stage the qualifications provided by higher education. The proposed innovative solution consists in the fact that the proposed information system combines the advantages of content management system (CMS with learning content management system (LCMS and with reusable learning objects (RLO. Thus, the architecture proposed in the research ensures the integration of a content management system with a portal for information, guidance and support in making a professional project. The integration enables correlation of competences with content areas and specific items from various teaching subjects, thus evaluating the usefulness for this registry from learning/educational perspective. Using the proposed information system in enables correlation among qualifications, content of educational program and continuous self-evaluation opportunities, which facilitate monitoring of progress and adjustment of learning content.

  10. Instructor qualification for radiation safety training at a national laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Trinoskey, P.A.

    1994-10-01

    Prior to 1993, Health Physics Training (HPT) was conducted by the Lawrence Livermore National Laboratory (LLNL) health physics group. The job requirements specified a Masters Degree and experience. In fact, the majority of Health Physicists in the group were certified by the American Board of Health Physics. Under those circumstances, it was assumed that individuals in the group were technically qualified and the HPT instructor qualification stated that. In late 1993, the Health Physics Group at the LLNL was restructured and the training function was assigned to the training group. Additional requirements for training were mandated by the Department of Energy (DOE), which would necessitate increasing the existing training staff. With the need to hire, and the policy of reassignment of employees during downsizing, it was imperative that formal qualification standards be developed for technical knowledge. Qualification standards were in place for instructional capability. In drafting the new training qualifications for instructors, the requirements of a Certified Health Physicists had to be modified due to supply and demand. Additionally, for many of the performance-based training courses, registration by the National Registry of Radiation Protection Technologists is more desirable. Flexibility in qualification requirements has been incorporated to meet the reality of ongoing training and the compensation for desirable skills of individuals who may not meet all the criteria. The qualification requirements for an instructor rely on entry-level requirements and emphasis on goals (preferred) and continuing development of technical and instructional capabilities.

  11. The preservation of genetic resources of the vine requires cohabitation between institutional clonal selection, mass selection and private clonal selection

    Directory of Open Access Journals (Sweden)

    Roby Jean-Philippe

    2014-01-01

    Full Text Available Clonal selection allows control of virus diseases and selection of genotypes on agronomic, viticultural or enological criteria. Clonal selection has the major drawback that it impoverishes genetic diversity and exposes growers to environmental instability of clones (genotype X environment interaction. Clonal selection has become the almost unique way of propagating plant material for vineyards, hence threatening the genetic diversity of the grapevine. For major grapevine varieties, some genetic diversity is maintained in institutional collections. However, this way of conservation is insufficiently developed, it is expensive and remains fragile. A cost effective way to preserve intra-varietal diversity is to maintain a limited proportion of mass selection in vine propagation. Private clonal selection can also contribute, in a more limited way, in maintaining genetic resources. Another approach to carry out conservation and selection of grapevine is the methodology followed in Portugal. This strategy is exemplified with the conservation/selection of an ancient Portuguese variety. The work begins with the “ex situ” conservation of a representative sample of the intravarietal diversity of the variety, which, in practice, corresponds to a large field trial with hundreds of clones under an experimental design suitable for reducing random variation of quantitative traits. From evaluating those traits (yield and must quality traits, the intravarietal diversity is quantified and the range of the predicted genotypic effects for each of those traits is analyzed. Different mass selections (polyclonal selections are carried out for distribution and planting of new vineyards. These different mass selections provide high economic gains and also the preservation of diversity in a complementary manner to that which started the work on-farm conservation.

  12. Staubli TX-90XL robot qualification at the LLIHE.

    Energy Technology Data Exchange (ETDEWEB)

    Covert, Timothy Todd

    2010-10-01

    The Light Initiated High Explosive (LIHE) Facility uses a robotic arm to spray explosive material onto test items for impulse tests. In 2007, the decision was made to replace the existing PUMA 760 robot with the Staubli TX-90XL. A qualification plan was developed and implemented to verify the safe operating conditions and failure modes of the new system. The robot satisfied the safety requirements established in the qualification plan. A performance issue described in this report remains unresolved at the time of this publication. The final readiness review concluded the qualification of this robot at the LIHE facility.

  13. PAPS: A Scalable Framework for Prioritization and Partial Selection of Security Requirements

    OpenAIRE

    Mougouei, Davoud

    2017-01-01

    Owing to resource constraints, the existing prioritization and selection techniques for software security requirements (countermeasures) find a subset of higher-priority security requirements ignoring lower-priority requirements or postponing them to the future releases. Ignoring or postponing security requirements however, may on one hand leave some of the security threats (vulnerabilities) unattended and on the other hand influence other security requirements that rely on the ignored or pos...

  14. Qualification of NDT systems for in-service inspections of nuclear power plant pressure vessels; Ydinvoimalaitosten paineastioiden maeaeraeaikaistarkastuksissa kaeytettaevien NDT-jaerjestelmien paetevoeinti

    Energy Technology Data Exchange (ETDEWEB)

    Elfving, K

    1998-11-01

    The goal of this study is to determine the requirements of the in-service inspection qualification in Europe, their feasibility in practice and to find out possible manufacture defects in test pieces used in practical trials. The literature study consists of qualification requirements set by European regulatory bodies and by the European nuclear power utilities. Also a brief summary of qualification requirements set by ASME Code, Section XI and comparison between ASME and European qualification requirements is included 24 refs.

  15. Refining the Policy for Timing of Kidney Transplant Waitlist Qualification

    Directory of Open Access Journals (Sweden)

    Benjamin J. Lee, MD

    2017-08-01

    Conclusions. The kidney transplantation policies should be revised, such that timing of waitlist qualification is more standardized. We suggest that mention of using calculated creatinine clearance be dropped from the Organ Procurement and Transplantation Network policy wording and the units to quantify kidney function be changed to mL/min per 1.73 m2. Some consideration should be given to whether requiring persistently reduced renal function would better identify patients most likely to benefit from earlier waitlist qualification.

  16. Process of establishing design requirements and selecting alternative configurations for conceptual design of a VLA

    Directory of Open Access Journals (Sweden)

    Bo-Young Bae

    2017-04-01

    Full Text Available In this study, a process for establishing design requirements and selecting alternative configurations for the conceptual phase of aircraft design has been proposed. The proposed process uses system-engineering-based requirement-analysis techniques such as objective tree, analytic hierarchy process, and quality function deployment to establish logical and quantitative standards. Moreover, in order to perform a logical selection of alternative aircraft configurations, it uses advanced decision-making methods such as morphological matrix and technique for order preference by similarity to the ideal solution. In addition, a preliminary sizing tool has been developed to check the feasibility of the established performance requirements and to evaluate the flight performance of the selected configurations. The present process has been applied for a two-seater very light aircraft (VLA, resulting in a set of tentative design requirements and two families of VLA configurations: a high-wing configuration and a low-wing configuration. The resulting set of design requirements consists of three categories: customer requirements, certification requirements, and performance requirements. The performance requirements include two mission requirements for the flight range and the endurance by reflecting the customer requirements. The flight performances of the two configuration families were evaluated using the sizing tool developed and the low-wing configuration with conventional tails was selected as the best baseline configuration for the VLA.

  17. Uber die Vereinbarkeit individueller Bildungsbedurfnisse und betrieblicher Qualifikationsanforderungen (On the Compatibility of Individual Needs for Education and Employment-Related Qualification Requirements).

    Science.gov (United States)

    Heid, Helmut

    1999-01-01

    States that a tendency has developed to orientate educational-practical acting using learners' educational needs, while representatives of the employment system deduce political and practical educational maxims from requirements that result from economic structural changes. Defines the instructional importance of individual educational needs and…

  18. An integrated approach for requirement selection and scheduling in software release planning

    NARCIS (Netherlands)

    Li, C.; van den Akker, Marjan; Brinkkemper, Sjaak; Diepen, Guido

    It is essential for product software companies to decide which requirements should be included in the next release and to make an appropriate time plan of the development project. Compared to the extensive research done on requirement selection, very little research has been performed on time

  19. Heat Treatment Procedure Qualification for Steel Castings

    Energy Technology Data Exchange (ETDEWEB)

    Mariol Charles; Nicholas Deskevich; Vipin Varkey; Robert Voigt; Angela Wollenburg

    2004-04-29

    Heat treatment practices used by steel foundries have been carefully studied as part of comprehensive heat treatment procedure qualification development trials. These studies highlight the relationships between critical heat treatment process control parameters and heat treatment success. Foundry heat treatment trials to develop heat treatment procedure qualifications have shed light on the relationship between heat treatment theory and current practices. Furnace load time-temperature profiles in steel foundries exhibit significant differences depending on heat treatment equipment, furnace loading practice, and furnace maintenance. Time-temperature profiles of furnace control thermocouples can be very different from the time-temperature profiles observed at the center of casting loads in the furnace. Typical austenitization temperatures and holding times used by steel foundries far exceed what is required for transformation to austenite. Quenching and hardenability concepts were also investigated. Heat treatment procedure qualification (HTPQ) schema to demonstrate heat treatment success and to pre-qualify other alloys and section sizes requiring lesser hardenability have been developed. Tempering success is dependent on both tempering time and temperature. As such, furnace temperature uniformity and control of furnace loading during tempering is critical to obtain the desired mechanical properties. The ramp-up time in the furnace prior to the establishment of steady state heat treatment conditions contributes to the extent of heat treatment performed. This influence of ramp-up to temperature during tempering has been quantified.

  20. Heat Treatment Procedure Qualification for Steel Castings

    Energy Technology Data Exchange (ETDEWEB)

    Voigt, Robert C. [Pennsylvania State Univ., University Park, PA (United States); Charles, Mariol [Pennsylvania State Univ., University Park, PA (United States); Deskevich, Nicholas [Pennsylvania State Univ., University Park, PA (United States); Varkey, Vipin [Pennsylvania State Univ., University Park, PA (United States); Wollenburg, Angela [Pennsylvania State Univ., University Park, PA (United States)

    2004-10-15

    Heat treatment practices used by steel foundries have been carefully studied as part of comprehensive heat treatment procedure qualification development trials. These studies highlight the relationships between critical heat treatment process control parameters and heat treatment success. Foundry heat treatment trials to develop heat treatment procedure qualifications have shed light on the relationship between heat treatment theory and current practices. Furnace load time-temperature profiles in steel foundries exhibit significant differences depending on heat treatment equipment, furnace loading practice, and furnace maintenance. Time-temperature profiles of furnace control thermocouples can be very different from the time-temperature profiles observed at the center of casting loads in the furnace. Typical austenitization temperatures and holding times used by steel foundries far exceed what is required for transformation to austenite. Quenching and hardenability concepts were also investigated. Heat treatment procedure qualification (HTPQ) schema to demonstrate heat treatment success and to pre-qualify other alloys and section sizes requiring lesser hardenability have been developed. Tempering success is dependent on both tempering time and temperature. As such, furnace temperature uniformity and control of furnace loading during tempering is critical to obtain the desired mechanical properties. The ramp-up time in the furnace prior to the establishment of steady state heat treatment conditions contributes to the extent of heat treatment performed. This influence of ramp-up to temperature during tempering has been quantified.

  1. Regulatory requirements for nuclear power plant site selection in Malaysia-a review.

    Science.gov (United States)

    Basri, N A; Hashim, S; Ramli, A T; Bradley, D A; Hamzah, K

    2016-12-01

    Malaysia has initiated a range of pre-project activities in preparation for its planned nuclear power programme. Clearly one of the first steps is the selection of sites that are deemed suitable for the construction and operation of a nuclear power plant. Here we outline the Malaysian regulatory requirements for nuclear power plant site selection, emphasizing details of the selection procedures and site characteristics needed, with a clear focus on radiation safety and radiation protection in respect of the site surroundings. The Malaysia Atomic Energy Licensing Board (AELB) site selection guidelines are in accord with those provided in International Atomic Energy Agency (IAEA) and United Stated Nuclear Regulatory Commission (USNRC) documents. To enhance the suitability criteria during selection, as well as to assist in the final decision making process, possible assessments using the site selection characteristics and information are proposed.

  2. IDENTIFYING OPERATIONAL REQUIREMENTS TO SELECT SUITABLE DECISION MODELS FOR A PUBLIC SECTOR EPROCUREMENT DECISION SUPPORT SYSTEM

    Directory of Open Access Journals (Sweden)

    Mohamed Adil

    2014-10-01

    Full Text Available Public sector procurement should be a transparent and fair process. Strict legal requirements are enforced on public sector procurement to make it a standardised process. To make fair decisions on selecting suppliers, a practical method which adheres to legal requirements is important. The research that is the base for this paper aimed at identifying a suitable Multi-Criteria Decision Analysis (MCDA method for the specific legal and functional needs of the Maldivian Public Sector. To identify such operational requirements, a set of focus group interviews were conducted in the Maldives with public officials responsible for procurement decision making. Based on the operational requirements identified through focus groups, criteria-based evaluation is done on published MCDA methods to identify the suitable methods for e-procurement decision making. This paper describes the identification of the operational requirements and the results of the evaluation to select suitable decision models for the Maldivian context.

  3. 23 CFR 1350.4 - Qualification requirements.

    Science.gov (United States)

    2010-04-01

    ... impacted by, motorcycle safety issues; and (iv) Incorporate a strategic communications plan that— (A... collaboration among agencies and organizations responsible for, or impacted by, motorcycle safety issues; and (v... training course that is offered throughout the State, provides a formal program of instruction in accident...

  4. 75 FR 22178 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-27

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in the... individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency has...

  5. 75 FR 39618 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-07-09

    ...-24015; FMCSA-2007-0071; FMCSA-2008-0021] Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in the... individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency has...

  6. 75 FR 22179 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-04-27

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Renewals; Vision AGENCY...: FMCSA previously announced its decision to renew the exemptions from the vision requirement in the... individuals from the vision requirement if the exemptions granted will not compromise safety. The Agency has...

  7. 75 FR 1453 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-01-11

    ...-2007-27897; FMCSA- 2007-28695; FMCSA-2007-29019] Qualification of Drivers; Exemption Renewals; Vision.... SUMMARY: FMCSA previously announced its decision to renew the exemptions from the vision requirement in... exempt individuals from the vision requirement if the exemptions granted will not compromise safety. The...

  8. 46 CFR 2.75-70 - Welding procedure and performance qualifications.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Welding procedure and performance qualifications. 2.75... for Construction Personnel § 2.75-70 Welding procedure and performance qualifications. (a) Welding... requirements for the welding of pressure piping, boilers, pressure vessels, and nonpressure vessel type tanks...

  9. 10 CFR 50.120 - Training and qualification of nuclear power plant personnel.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Training and qualification of nuclear power plant... Training and qualification of nuclear power plant personnel. (a) Applicability. The requirements of this... each holder of a combined license issued under part 52 of this chapter for a nuclear power plant of the...

  10. Large Bore Powder Gun Qualification (U)

    Energy Technology Data Exchange (ETDEWEB)

    Rabern, Donald A. [Los Alamos National Laboratory; Valdiviez, Robert [Los Alamos National Laboratory

    2012-04-02

    A Large Bore Powder Gun (LBPG) is being designed to enable experimentalists to characterize material behavior outside the capabilities of the NNSS JASPER and LANL TA-55 PF-4 guns. The combination of these three guns will create a capability to conduct impact experiments over a wide range of pressures and shock profiles. The Large Bore Powder Gun will be fielded at the Nevada National Security Site (NNSS) U1a Complex. The Complex is nearly 1000 ft below ground with dedicated drifts for testing, instrumentation, and post-shot entombment. To ensure the reliability, safety, and performance of the LBPG, a qualification plan has been established and documented here. Requirements for the LBPG have been established and documented in WE-14-TR-0065 U A, Large Bore Powder Gun Customer Requirements. The document includes the requirements for the physics experiments, the gun and confinement systems, and operations at NNSS. A detailed description of the requirements is established in that document and is referred to and quoted throughout this document. Two Gun and Confinement Systems will be fielded. The Prototype Gun will be used primarily to characterize the gun and confinement performance and be the primary platform for qualification actions. This gun will also be used to investigate and qualify target and diagnostic modifications through the life of the program (U1a.104 Drift). An identical gun, the Physics Gun, will be fielded for confirmatory and Pu experiments (U1a.102D Drift). Both guns will be qualified for operation. The Gun and Confinement System design will be qualified through analysis, inspection, and testing using the Prototype Gun for the majority of process. The Physics Gun will be qualified through inspection and a limited number of qualification tests to ensure performance and behavior equivalent to the Prototype gun. Figure 1.1 shows the partial configuration of U1a and the locations of the Prototype and Physics Gun/Confinement Systems.

  11. The proto-oncogene MYC is required for selection in the germinal center and cyclic reentry.

    Science.gov (United States)

    Dominguez-Sola, David; Victora, Gabriel D; Ying, Carol Y; Phan, Ryan T; Saito, Masumichi; Nussenzweig, Michel C; Dalla-Favera, Riccardo

    2012-11-01

    After antigenic challenge, B cells enter the dark zone (DZ) of germinal centers (GCs) to proliferate and hypermutate their immunoglobulin genes. Mutants with greater affinity for the antigen are positively selected in the light zone (LZ) to either differentiate into plasma and memory cells or reenter the DZ. The molecular circuits that govern positive selection in the GC are not known. We show here that the GC reaction required biphasic regulation of expression of the cell-cycle regulator c-Myc that involved its transient induction during early GC commitment, its repression by Bcl-6 in DZ B cells and its reinduction in B cells selected for reentry into the DZ. Inhibition of c-Myc in vivo led to GC collapse, which indicated an essential role for c-Myc in GCs. Our results have implications for the mechanism of GC selection and the role of c-Myc in lymphomagenesis.

  12. Qualification of a precision pattern dispenser.

    Science.gov (United States)

    Van Ammel, Raf; Sobiech-Matura, Katarzyna; Wätjen, Uwe; Vercammen, Tom; Castelein, Pieter; Wuyts, Roel; Paul, Johan

    2017-06-16

    In order to automate sample preparation processes, a precision pattern dispenser was designed to reproducibly dispense radioactive solutions at pre-defined positions. It is composed of an automatic liquid sample handling unit coupled to an XYZ table. Qualification tests were conducted to evaluate the performance of the instrument and to assess the compliance with the requirements, in particular trueness (< 2%) and repeatability (< 1%). The instrument allows preparing sources in different source holders and on air filters, in a fast and accurate way. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. Data Qualification Report: Calculated Porosity and Porosity-Derived Values for Lithostratigraphic Units for use on the Yucca Mountain Project

    Energy Technology Data Exchange (ETDEWEB)

    P. Sanchez

    2001-05-30

    The qualification is being completed in accordance with the Data Qualification Plan DQP-NBS-GS-000006, Rev. 00 (CRWMS M&O 2001). The purpose of this data qualification activity is to evaluate for qualification the unqualified developed input and porosity output included in Data Tracking Number (DTN) M09910POROCALC.000. The main output of the analyses documented in DTN M09910POROCALC.000 is the calculated total porosity and effective porosity for 40 Yucca Mountain Project boreholes. The porosity data are used as input to Analysis Model Report (AMR) 10040, ''Rock Properties Model'' (MDL-NBS-GS-000004, Rev. 00), Interim Change Notice [ICN] 02 (CRWMS M&O 2000b). The output from the rock properties model is used as input to numerical physical-process modeling within the context of a relationship developed in the AMR between hydraulic conductivity, bound water and zeolitic zones for use in the unsaturated zone model. In accordance with procedure AP-3.15Q, the porosity output is not used in the direct calculation of Principal Factors for post-closure safety or disruptive events. The original source for DTN M09910POROCALC.000 is a Civilian Radioactive Waste Management System (CRWMS) Management and Operating Contractor (M&O) report, ''Combined Porosity from Geophysical Logs'' (CRWMS M&O 1999a and hereafter referred to as Rael 1999). That report recalculated porosity results for both the historical boreholes covered in Nelson (1996), and the modern boreholes reported in CRWMS M&O (1996a,b). The porosity computations in Rael (1999) are based on density-porosity mathematical relationships requiring various input parameters, including bulk density, matrix density and air and/or fluid density and volumetric water content. The main output is computed total porosity and effective porosity reported on a foot-by-foot basis for each borehole, although volumetric water content is derived from neutron data as an interim output. This qualification

  14. Qualification tests for PWR control element drive mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Kim, In Yong; Jin, Choon Eon; Choi Suhn [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1996-01-01

    It is necessary to perform the qualification test for the magnetic jack type CEDM to show the design compatibility because the CEDM is composed of many mechanical and electrical components complicatedly. ABB-CE performed various qualification tests during the development of the System80 CEDM to which Korea Standard Nuclear Plant (KSNP) CEDM referred. The qualification test for the CEDM is classified into the performance test and the dynamic test. The performance test is to verify operability of the CEDM, and the dynamic test is to find dynamic characteristics and to verify the structural integrity if the CEDM for the seismic accidents. Described in this report are the test requirements, the test facilities and the test methods for the performance and the dynamic qualification tests of the PWR magnetic jack type CEDM. The impacts of the design changes in the Korea Next Generation Reactor (KNGR) on the KSNP CEDM were analyzed to present the necessity for the tests. This report also proposes the facilities to perform the tests in KAERI including reasonable schedule for the tests. Attached to this report is the summary of qualification tests of System 80 CEDM performed by ABB-CE. 20 figs., 16 tabs., 21 refs. (Author) .new.

  15. Selection of the Taylor-Saffman bubble does not require surface tension.

    Science.gov (United States)

    Vasconcelos, Giovani L; Mineev-Weinstein, Mark

    2014-06-01

    A new general class of exact solutions is presented for the time evolution of a bubble of arbitrary initial shape in a Hele-Shaw cell when surface tension effects are neglected. These solutions are obtained by conformal mapping the viscous flow domain to an annulus in an auxiliary complex plane. It is then demonstrated that the only stable fixed point (attractor) of the nonsingular bubble dynamics corresponds precisely to the selected pattern. This thus shows that, contrary to the established theory, bubble selection in a Hele-Shaw cell does not require surface tension. The solutions reported here significantly extend previous results for a simply connected geometry (finger) to a doubly connected one (bubble). We conjecture that the same selection rule without surface tension holds for Hele-Shaw flows of arbitrary connectivity.

  16. Selection of the battery pack parameters for an electric vehicle based on performance requirements

    Science.gov (United States)

    Koniak, M.; Czerepicki, A.

    2017-06-01

    Each type of vehicle has specific power requirements. Some require a rapid charging, other make long distances between charges, but a common feature is the longest battery life time. Additionally, the battery is influenced by factors such as temperature, depth of discharge and the operation current. The article contain the parameters of chemical cells that should be taken into account during the design of the battery for a specific application. This is particularly important because the batteries are not properly matched and can wear prematurely and cause an additional costs. The method of selecting the correct cell type should take previously discussed features and operating characteristics of the vehicle into account. The authors present methods of obtaining such characteristics along with their assessment and examples. Also there has been described an example of the battery parameters selection based on design assumptions of the vehicle and the expected performance characteristics. Selecting proper battery operating parameters is important due to its impact on the economic result of investments in electric vehicles. For example, for some Li-Ion technologies, the earlier worn out of batteries in a fleet of cruise boats or buses having estimated lifetime of 10 years is not acceptable, because this will cause substantial financial losses for the owner of the rolling stock. The presented method of choosing the right cell technology in the selected application, can be the basis for making the decision on future battery technical parameters.

  17. 14 CFR 135.247 - Pilot qualifications: Recent experience.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot qualifications: Recent experience... TRANSPORTATION (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT...

  18. 14 CFR 135.243 - Pilot in command qualifications.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot in command qualifications. 135.243... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Flight...

  19. 14 CFR 135.245 - Second in command qualifications.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Second in command qualifications. 135.245... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: COMMUTER AND ON DEMAND OPERATIONS AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Flight...

  20. 75 FR 60862 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-10-01

    ...-0174] Qualification of Drivers; Exemption Renewals; Vision AGENCY: Federal Motor Carrier Safety... decision to renew the exemptions from the vision requirement in the Federal Motor Carrier Safety Regulations for 18 individuals. FMCSA has statutory authority to exempt individuals from the vision...

  1. 75 FR 70078 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2010-11-16

    ..., complete loss of vision, loss of an eye, macular scarring and prosthesis. In most cases, their eye... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision.... SUMMARY: FMCSA announces its decision to exempt 15 individuals from the vision requirement in the Federal...

  2. 29 CFR 1910.410 - Qualifications of dive team.

    Science.gov (United States)

    2010-07-01

    ... Requirements § 1910.410 Qualifications of dive team. (a) General. (1) Each dive team member shall have the... physiology. (b) Assignments. (1) Each dive team member shall be assigned tasks in accordance with the... assigned diving operation. General Operations Procedures ...

  3. 46 CFR 56.70-20 - Qualification, general.

    Science.gov (United States)

    2010-10-01

    ... shall comply with the requirements of section IX of the ASME Boiler and Pressure Vessel Code... 46 Shipping 2 2010-10-01 2010-10-01 false Qualification, general. 56.70-20 Section 56.70-20 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PIPING SYSTEMS AND...

  4. 46 CFR 56.75-20 - Brazing qualification.

    Science.gov (United States)

    2010-10-01

    ... brazing operators shall be in accordance with the requirements of part C, Section IX of the ASME Boiler and Pressure Vessel Code (incorporated by reference; see 46 CFR 56.01-2) and part 57 of this... 46 Shipping 2 2010-10-01 2010-10-01 false Brazing qualification. 56.75-20 Section 56.75-20...

  5. 78 FR 38435 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-06-26

    ... safety mandated by the statutes. Qualifications of Applicants Wayne A. Beebe Mr. Beebe, 52, has had ITDM... Mr. Beebe understands diabetes management and monitoring, has stable control of his diabetes using insulin, and is able to drive a CMV safely. Mr. Beebe meets the requirements of the vision standard at 49...

  6. 77 FR 3549 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-01-24

    ... [Docket No. FMCSA-2011-0368] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY... from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  7. 77 FR 59447 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ... [Docket No. FMCSA-2012-0281] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY... from the diabetes mellitus requirement; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  8. Ecosystem-based fisheries management requires a change to the selective fishing philosophy

    Science.gov (United States)

    Zhou, Shijie; Smith, Anthony D. M.; Punt, André E.; Richardson, Anthony J.; Gibbs, Mark; Fulton, Elizabeth A.; Pascoe, Sean; Bulman, Catherine; Bayliss, Peter; Sainsbury, Keith

    2010-01-01

    Globally, many fish species are overexploited, and many stocks have collapsed. This crisis, along with increasing concerns over flow-on effects on ecosystems, has caused a reevaluation of traditional fisheries management practices, and a new ecosystem-based fisheries management (EBFM) paradigm has emerged. As part of this approach, selective fishing is widely encouraged in the belief that nonselective fishing has many adverse impacts. In particular, incidental bycatch is seen as wasteful and a negative feature of fishing, and methods to reduce bycatch are implemented in many fisheries. However, recent advances in fishery science and ecology suggest that a selective approach may also result in undesirable impacts both to fisheries and marine ecosystems. Selective fishing applies one or more of the “6-S” selections: species, stock, size, sex, season, and space. However, selective fishing alters biodiversity, which in turn changes ecosystem functioning and may affect fisheries production, hindering rather than helping achieve the goals of EBFM. We argue here that a “balanced exploitation” approach might alleviate many of the ecological effects of fishing by avoiding intensive removal of particular components of the ecosystem, while still supporting sustainable fisheries. This concept may require reducing exploitation rates on certain target species or groups to protect vulnerable components of the ecosystem. Benefits to society could be maintained or even increased because a greater proportion of the entire suite of harvested species is used. PMID:20435916

  9. 14 CFR 121.913 - Qualification curriculum.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Qualification curriculum. 121.913 Section 121.913 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED... Qualification curriculum. Each qualification curriculum must contain training, evaluation, and certification...

  10. DEVELOPING THE NATIONAL QUALIFICATIONS FRAMEWORK: KYRGYZ EXPERIENCE OF QUALIFICATIONS ANALYSIS IN THE AGRICULTURAL SECTOR

    Directory of Open Access Journals (Sweden)

    Мasuma I. Bashirova

    2014-01-01

    Full Text Available The paper reveals the research outcomes concerning the qualifications requirements of the Kyrgyz Republic’s agricultural sector; the significance of the given sector and lack of competent specialists determine the research relevance. The methodology bases of quantitative and qualitative human resources analysis involved a traditional sociological survey and innovative methods of functional analysis. The research findings can be used for balancing the labor marker supply and demand, and ensure, therefore, the effective personnel management in agricultural industry. On the other hand, the above findings can improve the vocational training programs and mechanisms of training quality assessment to align them with the employers’ requirements.

  11. A qualitative inquiry of educational requirements of selected professions in the Oklahoma aerospace industry

    Science.gov (United States)

    Walker, Casey Jerry Kennon

    Interview of incumbents of intellectual capital positions at Boeing. The aerospace industry is a dynamic industry that requires continual skill updates to keep up with advancements in technology and operational trends within the industry. The purpose of this study was to examine intellectual capital requirements of selected professional positions within the Boeing Company in Oklahoma. Data obtained through interviews was used to determine if educational skills gaps existed. The findings of the study can be used to develop an aerospace educational pipeline based on collaborative relationships between industry and higher education to facilitate educational and training programs. Three broad research questions were used to address and support the findings of this study related to educational background, career progression, and gaps. A purposive sample of 10 professional positions was selected for interview using an interview guide containing 18 questions. Data was analyzed using manual coding techniques. Findings and conclusions. The study found that minimum education requirements for selected professional positions consisted of a bachelor's degree. Although the majority of participants identified a business degree as optimal, several participants indicated that an education background from multiple disciplines would provide the greatest benefit. Data from interviews showed educational degrees were not specialized enough and skills required to perform job functions were obtained through direct on the job experience or through corporate training. Indications from participant responses showed employees with a thorough knowledge of government acronyms had a decided advantage over those that did not. Recommendations included: expanding the study to multiple organizations by conducting a survey; expanding industry and academic partnerships; establishing a structured educational pipeline to fill critical positions; creating broad aerospace curricula degree programs tailored

  12. 24 CFR 3286.311 - Suspension or revocation of trainer's qualification.

    Science.gov (United States)

    2010-04-01

    ... records or information to HUD; (2) Refusing to submit information required to be submitted by the... qualification, the Secretary will consider the impact of the suspension or revocation on other affected parties...

  13. Helicopter-Ship Qualification Testing

    NARCIS (Netherlands)

    Hoencamp, A.

    2015-01-01

    The goal of this research project is to develop a novel test methodology which can be used for optimizing cost and time efficiency of helicopter-ship qualification testing without reducing safety. For this purpose, the so-called “SHOL-X” test methodology has been established, which includes the

  14. Hybrid Qualifications Country report Denmark

    DEFF Research Database (Denmark)

    Jørgensen, Christian Helms

    2010-01-01

    The report explores the institutional and functional relations between the higher education (tertiary sector) and vocational education (higher secondary education) and the labour market. In the report are included descriptions of the history, funding, outcomes, institutional realisation and term...... and range of hybrid qualifications in the national system. In addition some recommendations for constructive further developments are given....

  15. Mutual Recogniton of Professional Qualifications

    DEFF Research Database (Denmark)

    Enemark, Stig; Plimmer, Francis

    The publication aims to review the concept of mutual recognition of qualifications within the world wide surveying community, and to develop a framework for the introduction of standards of global professional competence in this area. The publication also includes a number of case studies from...

  16. Raccoon spatial requirements and multi-scale habitat selection within an intensively managed central Appalachian forest

    Science.gov (United States)

    Owen, Sheldon F.; Berl, Jacob L.; Edwards, John W.; Ford, W. Mark; Wood, Petra Bohall

    2015-01-01

    We studied a raccoon (Procyon lotor) population within a managed central Appalachian hardwood forest in West Virginia to investigate the effects of intensive forest management on raccoon spatial requirements and habitat selection. Raccoon home-range (95% utilization distribution) and core-area (50% utilization distribution) size differed between sexes with males maintaining larger (2×) home ranges and core areas than females. Home-range and core-area size did not differ between seasons for either sex. We used compositional analysis to quantify raccoon selection of six different habitat types at multiple spatial scales. Raccoons selected riparian corridors (riparian management zones [RMZ]) and intact forests (> 70 y old) at the core-area spatial scale. RMZs likely were used by raccoons because they provided abundant denning resources (i.e., large-diameter trees) as well as access to water. Habitat composition associated with raccoon foraging locations indicated selection for intact forests, riparian areas, and regenerating harvest (stands managed forests in the central Appalachians.

  17. Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase.

    Science.gov (United States)

    Ersching, Jonatan; Efeyan, Alejo; Mesin, Luka; Jacobsen, Johanne T; Pasqual, Giulia; Grabiner, Brian C; Dominguez-Sola, David; Sabatini, David M; Victora, Gabriel D

    2017-06-20

    During antibody affinity maturation, germinal center (GC) B cells cycle between affinity-driven selection in the light zone (LZ) and proliferation and somatic hypermutation in the dark zone (DZ). Although selection of GC B cells is triggered by antigen-dependent signals delivered in the LZ, DZ proliferation occurs in the absence of such signals. We show that positive selection triggered by T cell help activates the mechanistic target of rapamycin complex 1 (mTORC1), which promotes the anabolic program that supports DZ proliferation. Blocking mTORC1 prior to growth prevented clonal expansion, whereas blockade after cells reached peak size had little to no effect. Conversely, constitutively active mTORC1 led to DZ enrichment but loss of competitiveness and impaired affinity maturation. Thus, mTORC1 activation is required for fueling B cells prior to DZ proliferation rather than for allowing cell-cycle progression itself and must be regulated dynamically during cyclic re-entry to ensure efficient affinity-based selection. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Establishment of functional requirements to DC-connected wind turbine and their use in concept selection

    DEFF Research Database (Denmark)

    Dincan, Catalin Gabriel; Kjær, Philip Carne; Chen, Yu-Hsing

    2017-01-01

    Offshore wind farms using medium voltage DC power collection promise an increase in efficiency and a reduced bill-of-material cost. One of the key components is the high power, medium voltage DC/DC converter located in the wind turbines. There are many suggested topologies in the state of the art...... required from the turbine DC converter and uses these to compare 6 distinct candidate circuit topologies. The end goal is not to select the best topology, but to narrow down from a vast list of options and give a method that will increase confidence and guide towards the characteristics of reliable design....

  19. The ASEAN economic community and medical qualification.

    Science.gov (United States)

    Kittrakulrat, Jathurong; Jongjatuporn, Witthawin; Jurjai, Ravipol; Jarupanich, Nicha; Pongpirul, Krit

    2014-12-01

    Background In the regional movement toward ASEAN Economic Community (AEC), medical professions including physicians can be qualified to practice medicine in another country. Ensuring comparable, excellent medical qualification systems is crucial but the availability and analysis of relevant information has been lacking. Objective This study had the following aims: 1) to comparatively analyze information on Medical Licensing Examinations (MLE) across ASEAN countries and 2) to assess stakeholders' view on potential consequences of AEC on the medical profession from a Thai perspective. Design To search for relevant information on MLE, we started with each country's national body as the primary data source. In case of lack of available data, secondary data sources including official websites of medical universities, colleagues in international and national medical student organizations, and some other appropriate Internet sources were used. Feasibility and concerns about validity and reliability of these sources were discussed among investigators. Experts in the region invited through HealthSpace.Asia conducted the final data validation. For the second objective, in-depth interviews were conducted with 13 Thai stakeholders, purposely selected based on a maximum variation sampling technique to represent the points of view of the medical licensing authority, the medical profession, ethicists and economists. Results MLE systems exist in all ASEAN countries except Brunei, but vary greatly. Although the majority has a national MLE system, Singapore, Indonesia, and Vietnam accept results of MLE conducted at universities. Thailand adopted the USA's 3-step approach that aims to check pre-clinical knowledge, clinical knowledge, and clinical skills. Most countries, however, require only one step. A multiple choice question (MCQ) is the most commonly used method of assessment; a modified essay question (MEQ) is the next most common. Although both tests assess candidate

  20. The ASEAN economic community and medical qualification

    Directory of Open Access Journals (Sweden)

    Jathurong Kittrakulrat

    2014-09-01

    Full Text Available Background: In the regional movement toward ASEAN Economic Community (AEC, medical professions including physicians can be qualified to practice medicine in another country. Ensuring comparable, excellent medical qualification systems is crucial but the availability and analysis of relevant information has been lacking. Objective: This study had the following aims: 1 to comparatively analyze information on Medical Licensing Examinations (MLE across ASEAN countries and 2 to assess stakeholders’ view on potential consequences of AEC on the medical profession from a Thai perspective. Design: To search for relevant information on MLE, we started with each country's national body as the primary data source. In case of lack of available data, secondary data sources including official websites of medical universities, colleagues in international and national medical student organizations, and some other appropriate Internet sources were used. Feasibility and concerns about validity and reliability of these sources were discussed among investigators. Experts in the region invited through HealthSpace.Asia conducted the final data validation. For the second objective, in-depth interviews were conducted with 13 Thai stakeholders, purposely selected based on a maximum variation sampling technique to represent the points of view of the medical licensing authority, the medical profession, ethicists and economists. Results: MLE systems exist in all ASEAN countries except Brunei, but vary greatly. Although the majority has a national MLE system, Singapore, Indonesia, and Vietnam accept results of MLE conducted at universities. Thailand adopted the USA's 3-step approach that aims to check pre-clinical knowledge, clinical knowledge, and clinical skills. Most countries, however, require only one step. A multiple choice question (MCQ is the most commonly used method of assessment; a modified essay question (MEQ is the next most common. Although both tests assess

  1. Data Qualification Report For: Thermodynamic Data File, DATA0.YMP.R0 For Geochemical Code, EQ3/6 

    Energy Technology Data Exchange (ETDEWEB)

    P.L. Cloke

    2001-10-16

    The objective of this work is to evaluate the adequacy of chemical thermodynamic data provided by Lawrence Livermore National Laboratory (LLNL) as DataO.ymp.ROA in response to an input request submitted under AP-3.14Q. This request specified that chemical thermodynamic data available in the file, Data0.com.R2, be updated, improved, and augmented for use in geochemical modeling used in Process Model Reports (PMRs) for Engineered Barrier Systems, Waste Form, Waste Package, Unsaturated Zone, and Near Field Environment, as well as for Performance Assessment. The data are qualified in the temperature range 0 to 100 C. Several Data Tracking Numbers (DTNs) associated with Analysis/Model Reports (AMR) addressing various aspects of the post-closure chemical behavior of the waste package and the Engineered Barrier System that rely on EQ316 outputs to which these data are used as input, are Principal Factor affecting. This qualification activity was accomplished in accordance with the AP-SIII.2Q using the Technical Assessment method. A development plan, TDP-EBS-MD-000044, was prepared in accordance with AP-2.13Q and approved by the Responsible Manager. In addition, a Process Control Evaluation was performed in accordance with AP-SV.1Q. The qualification method, selected in accordance with AP-SIII.2Q, was Technical Assessment. The rationale for this approach is that the data in File Data0.com.R2 are considered Handbook data and therefore do not themselves require qualification. Only changes to Data0.com.R2 required qualification. A new file has been produced which contains the database Data0.ymp.R0, which is recommended for qualification as a result of this action. Data0.ymp.R0 will supersede Data0.com.R2 for all Yucca Mountain Project (YMP) activities.

  2. Notch signaling in bulge stem cells is not required for selection of hair follicle fate

    Science.gov (United States)

    Demehri, Shadmehr; Kopan, Raphael

    2009-01-01

    Summary Notch signaling plays an important role in hair follicle maintenance, and it has been suggested that Notch is also required for follicular fate selection by adult hair follicle stem cells in the bulge. Here we demonstrate that, on the contrary, Notch signaling in bi-potential bulge stem cells or their uncommitted descendents acts to suppress the epidermal fate choice, thus ensuring follicular fate selection. To examine the role of Notch signaling in adult hair follicle stem cells, we used a Krt1-15-CrePR1 transgenic mouse line to delete Rbpj or all Notch proteins specifically in the bulge stem cells. We conclusively determined that in the absence of Notch signaling, bulge stem cell descendents retain their capacity to execute the follicular differentiation program but fail to maintain it owing to their genetic deficiency. The defect in terminal differentiation caused the diversion of Notch-deficient hair follicles to epidermal cysts, and the presence of wild-type cells could not prevent this conversion. Importantly, our analysis revealed that a functional Notch signaling pathway was required to block bulge stem cells from migrating into, and assuming the fate of, interfollicular epidermis. Taken together, our findings yield detailed insight into the function of Notch signaling in hair follicle stem cells and reveal the mechanism of the replacement of Notch-deficient adult hair follicles by epidermal cysts. PMID:19211676

  3. Are You Experienced The Case for Acquisition Professional Qualification Standards

    Science.gov (United States)

    2015-10-01

    was to translate the competencies into on-the- job tools and processes to develop “individual qualification plans.” All this was to be completed and...declaring the trainee proficient enough to perform the job on their own. Physicians are required to complete years of schooling and resi-dency training, as...perform acquisition jobs . Without such standards, it is difficult to define mini- mum requirements for senior acquisition positions, as well as to

  4. Qualification, knowledge and experience of dispensers working at community pharmacies in Pakistan

    OpenAIRE

    Hussain A; Ibrahim MIM

    2011-01-01

    Pharmacies are managed by a variety of dispensers in terms of qualification, knowledge and experience in Pakistan. Objective The study aimed to document the state of knowledge, experience and qualification of dispensers working at community pharmacies in Pakistan. Methods A comparative cross sectional study was conducted at a randomly selected sample of 371 pharmacies in the three cities of Pakistan. A structured questionnaire for data collection was developed and finalized by focused group d...

  5. Process qualification strategy for advances embedded non volatile memory technology - the Philips'0.18um embedded flash case

    NARCIS (Netherlands)

    Tao, Guoqiao; Scarpa, Andrea; van Dijk, Kitty; Kuper, F.G.

    2003-01-01

    A qualification strategy for advanced embedded non-volatile memory technology has been revealed. This strategy consists of: a thorough understanding of the requirements, extensive use and frequent update of the FMEA (failure mode effect analysis), a qualification plan with excellent coverage of all

  6. Process Qualification Strategy for Advances Embedded Non Volatile Memory Technology : The Philips' 0.18um Embedded Flash Case

    NARCIS (Netherlands)

    Tao, Guoqiao; Scarpa, Andrea; van Dijk, Kitty; Kuper, Fred G.

    2003-01-01

    A qualification strategy for advanced embedded non-volatile memory technology has been revealed. This strategy consists of: a thorough understanding of the requirements, extensive use and frequent update of the FMEA (failure mode effect analysis), a qualification plan with excellent coverage of all

  7. Utilizing a Russian Space Nuclear Reactor for a United States Space Mission: Flight Qualification Issues

    Science.gov (United States)

    Polansky, Gary F.; Schmidt, Glen L.; Reynolds, Edward L.; Schaefer, Edward D.; Ogloblin, Boris; Bocharov, Anatoly

    1994-07-01

    Space nuclear power and nuclear electric propulsion are considered important technologies for planetary exploration, as well as selected earth orbit applications. The Nuclear Electric Propulsion Space Test Program (NEPSTP) could provide an early flight demonstration of these technologies at relatively low cost through extensive use of existing Russian technology. The key element of Russian technology employed in the program is the Topaz II reactor. This space nuclear power system was built and flight qualified, though never tested in space, by the former Soviet Union. The NEPSTP is faced with many unique flight qualification issues. In general, the launch of a spacecraft employing a nuclear reactor power system will complicate many spacecraft qualification activities. However, the NEPSTP activities are further complicated because the reactor power system is a Russian design. Therefore, this program must deal not only with the unique flight qualification issues associated with space nuclear power, but also with differences between Russian and United States flight qualification procedures. This paper presents an overview of the NEPSTP. The program goals, the proposed mission, the spacecraft, and the Topaz II space nuclear power system are described. The subject of flight qualification is then examined. The inherent difficulties in qualifying a space reactor are described. The differences between United States and Russian flight qualification procedures are explored. A plan is then described to determine an appropriate flight qualification program for the Topaz II reactor to support a possible NEPSTP launch.

  8. Phosphate Sorption Characteristics and External P Requirements of Selected South African Soils

    Directory of Open Access Journals (Sweden)

    E. M. Gichangi

    2008-10-01

    Full Text Available The Transkei is the largest consolidated area in South Africa where land is held by smallholder farmers but little is known about the extent of phosphate fixation in the region. This study was conducted to determine the phosphate sorption properties and external P requirements (EPR of selected soils from the Transkei region, South Africa and to relate derived sorption values to selected soil parameters. The P sorption maxima and EPR values varied widely ranging from 192.3 to 909.1 mg P kg−1 and from 2 to 123 mg P kg−1−1 soil, respectively. Citrate dithionite bicarbonate-extractable aluminum explained most of the observed variations in P sorption. About 43% of the soils were found to be moderate P fixers and may need management interventions to ensure adequate P availability to crops. The single point sorption index accurately predicted the EPR of the soils obviating the need to use multiple point sorption isotherms. The results suggested that the use of blanket phosphate fertilizer recommendations may not be a good strategy for the region as it may lead to under-application or over-application of P in some areas.

  9. Room for both qualification and inclusion?

    DEFF Research Database (Denmark)

    Ringskou, Lea Thomsen; Gravesen, David Thore

    2017-01-01

    by an official agenda of qualification, where effectiveness and better academic results rules. To a certain content, this agenda collides with and dominates the political and pedagogical agenda of inclusion. The agenda of qualification effects the spaces and places for inclusion and the roles of the leisure time...... pedagogues. In our presentation, we discuss the encounter between these two agendas: Which places and pedagogical roles are emerging in the encounter or the field of tension between qualification and inclusion?...

  10. ITER CENTRAL SOLENOID COIL INSULATION QUALIFICATION

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, N N; Mann, T L; Miller, J R; Freudenberg, K D; Reed, R P; Walsh, R P; McColskey, J D; Evans, D

    2009-06-11

    An insulation system for ITER Central Solenoid must have sufficiently high electrical and structural strength. Design efforts to bring stresses in the turn and layer insulation within allowables failed. It turned out to be impossible to eliminate high local tensile stresses in the winding pack. When high local stresses can not be designed out, the qualification procedure requires verification of the acceptable structural and electrical strength by testing. We built two 4 x 4 arrays of the conductor jacket with two options of the CS insulation and subjected the arrays to 1.2 million compressive cycles at 60 MPa and at 76 K. Such conditions simulated stresses in the CS insulation. We performed voltage withstand tests and after end of cycling we measured the breakdown voltages between in the arrays. After that we dissectioned the arrays and studied micro cracks in the insulation. We report details of the specimens preparation, test procedures and test results.

  11. Statistical Methods for Material Characterization and Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Kercher, A.K.

    2005-04-01

    This document describes a suite of statistical methods that can be used to infer lot parameters from the data obtained from inspection/testing of random samples taken from that lot. Some of these methods will be needed to perform the statistical acceptance tests required by the Advanced Gas Reactor Fuel Development and Qualification (AGR) Program. Special focus has been placed on proper interpretation of acceptance criteria and unambiguous methods of reporting the statistical results. In addition, modified statistical methods are described that can provide valuable measures of quality for different lots of material. This document has been written for use as a reference and a guide for performing these statistical calculations. Examples of each method are provided. Uncertainty analysis (e.g., measurement uncertainty due to instrumental bias) is not included in this document, but should be considered when reporting statistical results.

  12. Statistical methods for material characterization and qualification

    Energy Technology Data Exchange (ETDEWEB)

    Hunn, John D [ORNL; Kercher, Andrew K [ORNL

    2005-01-01

    This document describes a suite of statistical methods that can be used to infer lot parameters from the data obtained from inspection/testing of random samples taken from that lot. Some of these methods will be needed to perform the statistical acceptance tests required by the Advanced Gas Reactor Fuel Development and Qualification (AGR) Program. Special focus has been placed on proper interpretation of acceptance criteria and unambiguous methods of reporting the statistical results. In addition, modified statistical methods are described that can provide valuable measures of quality for different lots of material. This document has been written for use as a reference and a guide for performing these statistical calculations. Examples of each method are provided. Uncertainty analysis (e.g., measurement uncertainty due to instrumental bias) is not included in this document, but should be considered when reporting statistical results.

  13. Cyclin D3 is selectively required for proliferative expansion of germinal center B cells.

    Science.gov (United States)

    Cato, Matthew H; Chintalapati, Suresh K; Yau, Irene W; Omori, Sidne A; Rickert, Robert C

    2011-01-01

    The generation of robust T-cell-dependent humoral immune responses requires the formation and expansion of germinal center structures within the follicular regions of the secondary lymphoid tissues. B-cell proliferation in the germinal center drives ongoing antigen-dependent selection and the generation of high-affinity class-switched plasma and memory B cells. However, the mechanisms regulating B-cell proliferation within this microenvironment are largely unknown. Here, we report that cyclin D3 is uniquely required for germinal center progression. Ccnd3(-/-) mice exhibit a B-cell-intrinsic defect in germinal center maturation and fail to generate an affinity-matured IgG response. We determined that the defect resulted from failed proliferative expansion of GL7(+) IgD(-) PNA(+) B cells. Mechanistically, sustained expression of cyclin D3 was found to be regulated at the level of protein stability and controlled by glycogen synthase kinase 3 in a cyclic AMP-protein kinase A-dependent manner. The specific defect in proliferative expansion of GL7(+) IgD(-) PNA(+) B cells in Ccnd3(-/-) mice defines an underappreciated step in germinal center progression and solidifies a role for cyclin D3 in the immune response, and as a potential therapeutic target for germinal center-derived B-cell malignancies.

  14. Balanced excitation and inhibition are required for high-capacity, noise-robust neuronal selectivity.

    Science.gov (United States)

    Rubin, Ran; Abbott, L F; Sompolinsky, Haim

    2017-10-17

    Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well as the robustness of attractor states of networks of neurons performing memory tasks. We find that robustness to output noise requires synaptic connections to be in a balanced regime in which excitation and inhibition are strong and largely cancel each other. We evaluate the conditions required for this regime to exist and determine the properties of networks operating within it. A plausible synaptic plasticity rule for learning that balances weight configurations is presented. Our theory predicts an optimal ratio of the number of excitatory and inhibitory synapses for maximizing the encoding capacity of balanced networks for given statistics of afferent activations. Previous work has shown that balanced networks amplify spatiotemporal variability and account for observed asynchronous irregular states. Here we present a distinct type of balanced network that amplifies small changes in the impinging signals and emerges automatically from learning to perform neuronal and network functions robustly. Published under the PNAS license.

  15. The Humanitarian Action Qualifications Framework: a quality assurance tool for the Humanitarian Sector

    Directory of Open Access Journals (Sweden)

    Bastiaan L. Aardema

    2014-07-01

    Full Text Available The article presents the European Universities on Professionalisation on Humanitarian Action (EUPRHA Project as an initiative that seeks to contribute to the professionalisation and quality assurance of the humanitarian sector. Its purpose is to explain the approach and the process leading to the development of the Humanitarian Action Qualifications Framework as an example of good practice for other sectors aiming at improving the recognition of qualifications as a precondition of academic and professional mobility. With this aim, it introduces the educational and humanitarian trends that led to this project: the move from transnational qualifications frameworks of which the European Qualifications Framework for Lifelong Learning (EQF is the best example to sectoral qualifications frameworks and the increasing demand from the sector seeking to determine the competencies and required skills of a professional humanitarian aid worker. Based on the EQF and the Tuning methodology the framework will act as a translating device to make national and sectoral qualifications more readable and promote humanitarian workers’ and learners’ mobility between countries and organisations. It will facilitate inter-system transparency and recognition of (non-formal and informal learning by linking occupations, skills, competences, and qualifications, thus benefiting the Humanitarian Sector as a whole.

  16. Risk factors for progressive neuromuscular scoliosis requiring posterior spinal fusion after selective dorsal rhizotomy.

    Science.gov (United States)

    Ravindra, Vijay M; Christensen, Michael T; Onwuzulike, Kaine; Smith, John T; Halvorson, Kyle; Brockmeyer, Douglas L; Walker, Marion L; Bollo, Robert J

    2017-11-01

    OBJECTIVE Selective dorsal rhizotomy (SDR) via limited laminectomy is an effective treatment of lower-extremity spasticity in the pediatric population. Children with spasticity are also at risk for neuromuscular scoliosis; however, specific risk factors for progressive spinal deformity requiring posterior spinal fusion (PSF) after SDR are unknown. The authors' goal was to identify potential risk factors. METHODS The authors performed a retrospective cohort study of patients who underwent SDR via limited laminectomy between 2003 and 2014 and who had at least 1 year of follow-up. They analyzed demographic, clinical, and radiographic variables to elucidate risk factors for progressive neuromuscular scoliosis. The primary outcome was need for PSF. RESULTS One hundred thirty-four patients underwent SDR and had at least 12 months of follow-up (mean 65 months); 48 patients (36%) had detailed pre- and postoperative radiographic data available. The mean age at surgery was 10 years (SD 5.1 years). Eighty-four patients (63%) were ambulatory before SDR, 109 (82%) underwent a single-level laminectomy, and a mean of 53% of the dorsal rootlets from L-1 to S-1 were sectioned. Fifteen patients (11.2%) subsequently required PSF for progressive deformity. Nonambulatory status (p 30° (p = 0.003) were significantly associated with PSF on univariate analysis, but no statistically significant correlation was found with any clinical or radiographic variable and PSF after SDR on multivariate regression analysis. CONCLUSIONS Patients with preoperative nonambulatory status and Cobb angle > 30° may be at risk for progressive spinal deformity requiring PSF after SDR. These are well-known risk factors for progressive deformity in children with spasticity in general. Although our analysis suggests SDR via limited laminectomy may not significantly accelerate the development of neuromuscular scoliosis, further case-control studies are critical to elucidate the impact of SDR on spinal deformity.

  17. Team Formation under Normal versus Crisis Situations: Leaders’ Assessments of Task Requirements and Selection of Team Members

    Science.gov (United States)

    2007-06-01

    Leaders’ Assessments of Task Requirements and Selection of Team Members By: Georgios Baltos , and Zoi Mitsopoulou June 2007...SELECTION OF TEAM MEMBERS Georgios Baltos , Lieutenant, Hellenic Navy Zoi Mitsopoulou, Lieutenant Junior Grade, Hellenic Navy Submitted...Authors: _____________________________________ Georgios Baltos _____________________________________ Zoi Mitsopoulou

  18. Qualification of phased array ultrasonic examination on T-joint weld of austenitic stainless steel for ITER vacuum vessel

    Energy Technology Data Exchange (ETDEWEB)

    Kim, G.H. [ITER Korea, National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Park, C.K., E-mail: love879@hanmail.net [ITER Korea, National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Jin, S.W.; Kim, H.S.; Hong, K.H.; Lee, Y.J.; Ahn, H.J.; Chung, W. [ITER Korea, National Fusion Research Institute, Daejeon 305-333 (Korea, Republic of); Jung, Y.H.; Roh, B.R. [Hyundai Heavy Industries Co. Ltd., Ulsan 682-792 (Korea, Republic of); Sa, J.W.; Choi, C.H. [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France)

    2016-11-01

    Highlights: • PAUT techniques has been developed by Hyundai Heavy Industries Co., LTD (HHI) and Korea Domestic Agency (KODA) to verify and settle down instrument calibration, test procedures, image processing, and so on. As the first step of development for PAUT technique, Several dozens of qualification blocks with artificial defects, which are parallel side drilled hole, embedded lack of fusion, embedded repair weld notch, and so on, have been designed and fabricated to simulate all potential defects during welding process. Real UT qualification group-1 for T-joint weld was successfully conducted in front of ANB inspector. • In this paper, remarkable progresses of UT qualification are presented for ITER vacuum vessel. - Abstract: Full penetration welding and 100% volumetric examination are required for all welds of pressure retaining parts of the ITER Vacuum Vessel (VV) according to RCC-MR Code and French Order of Nuclear Pressure Equipment (ESPN). The NDE requirement is one of important technical issues because radiographic examination (RT) is not applicable to many welding joints. Therefore the ultrasonic examination (UT) has been selected as an alternative method. Generally the UT on the austenitic welds is regarded as a great challenge due to the high attenuation and dispersion of the ultrasonic signal. In this paper, Phased array ultrasonic examination (PAUT) has been introduced on double sided T-shape austenitic welds of the ITER VV as a major NDE method as well as RT. Several dozens of qualification blocks with artificial defects, which are parallel side drilled hole, embedded lack of fusion, embedded repair weld notch, embedded parallel vertical notch, and so on, have been designed and fabricated to simulate all potential defects during welding process. PAUT techniques on the thick austenitic welds have been developed taking into account the acceptance criteria. Test procedure including calibration of equipment is derived and qualified through

  19. Motor Qualification for Long-Duration Mars Missions

    Science.gov (United States)

    Ramesham, Rajeshuni; Johnson, Michael R.; Cooper, Darren T.; Lau, Warren S.; Boykins, Kobie T.; Perret, Jonathan D.; Rainen, Richard A.; Greb, Andrea

    2013-01-01

    Qualification of motors for deep space under extreme thermal environments to be encountered during the Mars Science Laboratory (MSL) mission is required to verify the reliability and validate mission assurance requirements. The motor assembly must survive all ground operations, plus the nominal 670 Martian-day (or sol) mission that includes summer and winter seasons of the Mars environment. The motor assembly was tested and characterized under extreme temperature conditions with reference to hardware requirements. The motor assembly has been proved to be remarkably robust and displayed no sign of degradation due to the 3 X (three times per JPL design principles) thermal environmental exposure to the punishing Mars surface operations cycles. The motor characteristics obtained before, during, and post-test comparisons for the surface operations cycles are within measurement error of one another. The motors withstood/survived 2,010 extreme temperature cycles with a Delta T of 190 C deep temperature cycles, representing three times the expected thermal cycling exposure during the MSL surface operations. The qualification test hardware elements (A200 motor assembly, encoders, and resolver) have not shown any signs of degradation due to the PQV (Package Qualification and Verification) testing. The test hardware has demonstrated sufficient life to survive the deep thermal cycles associated with MSL mission surface operations for three lives.

  20. State variations in nursing home social worker qualifications.

    Science.gov (United States)

    Bern-Klug, Mercedes

    2008-01-01

    This is the first published account of state administrative code variations in nursing home social worker qualifications. It is important to review state codes because the majority of nursing homes in the U.S. have fewer than 121 beds and therefore are not required by the federal government to employ at least one full-time qualified social worker. States have the option of extending the federal regulations to homes with 120 or fewer beds, or strengthening the federal requirements in other ways. Findings indicate enormous variation in state requirements for qualifications of nursing home social workers, and even when states define a qualified nursing home social worker (not all do), they often exempt facilities from employing one. Seven states were found to be out of federal compliance. Research describing the qualifications of people employed in nursing home social services is called for, as well as research documenting effective psychosocial interventions, especially as they relate to resident quality of life. Ten recommendations for enhancing nursing home social work services are included.

  1. Type I interferon is selectively required by dendritic cells for immune rejection of tumors.

    Science.gov (United States)

    Diamond, Mark S; Kinder, Michelle; Matsushita, Hirokazu; Mashayekhi, Mona; Dunn, Gavin P; Archambault, Jessica M; Lee, Hsiaoju; Arthur, Cora D; White, J Michael; Kalinke, Ulrich; Murphy, Kenneth M; Schreiber, Robert D

    2011-09-26

    Cancer immunoediting is the process whereby the immune system suppresses neoplastic growth and shapes tumor immunogenicity. We previously reported that type I interferon (IFN-α/β) plays a central role in this process and that hematopoietic cells represent critical targets of type I IFN's actions. However, the specific cells affected by IFN-α/β and the functional processes that type I IFN induces remain undefined. Herein, we show that type I IFN is required to initiate the antitumor response and that its actions are temporally distinct from IFN-γ during cancer immunoediting. Using mixed bone marrow chimeric mice, we demonstrate that type I IFN sensitivity selectively within the innate immune compartment is essential for tumor-specific T cell priming and tumor elimination. We further show that mice lacking IFNAR1 (IFN-α/β receptor 1) in dendritic cells (DCs; Itgax-Cre(+)Ifnar1(f/f) mice) cannot reject highly immunogenic tumor cells and that CD8α(+) DCs from these mice display defects in antigen cross-presentation to CD8(+) T cells. In contrast, mice depleted of NK cells or mice that lack IFNAR1 in granulocytes and macrophage populations reject these tumors normally. Thus, DCs and specifically CD8α(+) DCs are functionally relevant targets of endogenous type I IFN during lymphocyte-mediated tumor rejection.

  2. Fast Qualification Methods for Microelectronic Packages

    NARCIS (Netherlands)

    Ma, X.

    2011-01-01

    This research aims at developing a knowledge based fast qualification method for moisture or thermally induced failure in microelectronic packages. Driven by the market competition and the need for shorter time to market, fast qualification tests are becoming more and more important for the

  3. 7 CFR 900.353 - Qualification standards.

    Science.gov (United States)

    2010-01-01

    ... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Procedure for Determining the Qualification of Cooperative Milk Marketing Associations § 900.353 Qualification standards... members; (c) have full authority in the sale of its members' milk; and (d) be engaged in making collective...

  4. Kiel sensors for the EPD instrument on-board Solar Orbiter - An overview of the qualification and acceptance test campaigns in phase D

    Science.gov (United States)

    Ravanbakhsh, A.; Kulkarni, S. R.; Panitzsch, L.; L Richards, M.; Munoz Hernandez, A.; Seimetz, L.; Elftmann, R.; Mahesh, Y.; Boden, S.; Boettcher, S. I.; Kulemzin, A.; Martin-Garcia, C.; Prieto, M.; Rodriguez-Pacheco, J.; Sanchez Prieto, S.; Schuster, B.; Steinhagen, J.; Tammen, J.; Wimmer-Schweingruber, R. F.

    2016-12-01

    Solar Orbiter is ESA's next solar and heliospheric mission which is planned to be launched in October 2018. The Energetic Particle Detector (EPD) on board on Solar Orbiter will provide key measurements for the Solar Orbiter science objectives. The EPD suite consists of four sensors; STEP, SIS, EPT and HET. The University of Kiel in Germany is responsible for the design, development, and building of STEP, and the two identical units EPT-HET 1 and EPT-HET 2. ESA's Solar Orbiter will explore the heliosphere at heliocentric distances between 0.28AU and 0.9AU and with inclination up to 38deg with respect to the Sun's equator. The spacecraft uses a heat shield to protect the bus and externally mounted instruments from the solar flux at the close distances to the sun. All three EPD-Kiel units are mounted externally but in different positions on the spacecraft outer deck. Although being protected by the spacecraft heat shield from high solar flux, EPT-HET1 and EPT-HET-2 as well as STEP experience a harsh environmental condition during the course of the mission. In addition due to the highly demanding science requirements, the qualification and acceptance test requirements of these externally mounted units are quite challenging. In this paper we present the development status of the EPT-HET 1, EPT-HET 2 and STEP sensors focusing on the activities performed in phase D and the qualification and acceptance test campaigns. The main objective of these test campaigns is to ensure and demonstrate the compatibility between the scientific requirements and the harsh environment expected during the mission. This paper includes the results summary of the environmental tests on the EPT-HET and STEP Proto-Qualification Models (PQMs) as well as Proto-Flight Models (PFMs). Only an adequate selection of environmental qualification and acceptance campaigns will guarantee the success of the scientific space missions.

  5. Methods Data Qualification Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    R. Sam Alessi; Tami Grimmett; Leng Vang; Dave McGrath

    2010-09-01

    The overall goal of the Next Generation Nuclear Plant (NGNP) Data Management and Analysis System (NDMAS) is to maintain data provenance for all NGNP data including the Methods component of NGNP data. Multiple means are available to access data stored in NDMAS. A web portal environment allows users to access data, view the results of qualification tests and view graphs and charts of various attributes of the data. NDMAS also has methods for the management of the data output from VHTR simulation models and data generated from experiments designed to verify and validate the simulation codes. These simulation models represent the outcome of mathematical representation of VHTR components and systems. The methods data management approaches described herein will handle data that arise from experiment, simulation, and external sources for the main purpose of facilitating parameter estimation and model verification and validation (V&V). A model integration environment entitled ModelCenter is used to automate the storing of data from simulation model runs to the NDMAS repository. This approach does not adversely change the why computational scientists conduct their work. The method is to be used mainly to store the results of model runs that need to be preserved for auditing purposes or for display to the NDMAS web portal. This interim report demonstrates the currently development of NDMAS for Methods data and discusses data and its qualification that is currently part of NDMAS.

  6. The qualification of electrical components and instrumentations relevant to safety

    CERN Document Server

    Zambardi, F

    1989-01-01

    Systems and components relevant to safety of nuclear power plants must maintain their functional integrity in order to assure accident prevention and mitigation. Redundancy is utilized against random failures, nevertheless care must be taken to avoid common failures in redundant components. Main sources of degradation and common cause failures consist in the aging effects and in the changes of environmental conditions which occur during the plant life and the postulated accidents. These causes of degradation are expected to be especially significant for instrumentation and electrical equipment, which can have a primary role in safety systems. The qualification is the methodology by which component safety requirements can be met against the above mentioned causes of degradation. In this report the connection between the possible, plant conditions and the resulting degradation effects on components is preliminarily addressed. A general characterization of the qualification is then presented. Basis, methods and ...

  7. Initial qualifications of adult educators – a comparative view

    DEFF Research Database (Denmark)

    Milana, Marcella; Larson, Anne; Søgaard Lund, Lise

    . These distinctions are reflected not only in the provision of adult education opportunities but also in public policies on adult learning. Consequently, initial education and training of adult educators as well as the policy on qualification of adult education professionals differs both between countries and between......General adult education, vocationally oriented adult education and liberal education often represent separated fields of public intervention. Each of these sectors is characterized by organizational features and a financial structure that support the pursuing of specific educational goals......, the paper will critically review current public policies in the field and problematise the role of existing education and training opportunities in providing those willing to teach adults in general adult education, vocationally oriented adult education or liberal education with the qualifications required...

  8. Sensor Selection method for IoT systems – focusing on embedded system requirements

    Directory of Open Access Journals (Sweden)

    Hirayama Masayuki

    2016-01-01

    Full Text Available Recently, various types of sensors have been developed. Using these sensors, IoT systems have become hot topics in embedded system domain. However, sensor selections for embedded systems are not well discussed up to now. This paper focuses on embedded system’s features and architecture, and proposes a sensor selection method which is composed seven steps. In addition, we applied the proposed method to a simple example – a sensor selection for computer scored answer sheet reader unit. From this case study, an idea to use FTA in sensor selection is also discussed.

  9. WTP Waste Feed Qualification: Glass Fabrication Unit Operation Testing Report

    Energy Technology Data Exchange (ETDEWEB)

    Stone, M. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Hanford Missions Programs; Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Process Technology Programs; Johnson, F. C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Engineering Process Development; Edwards, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL). Engineering Process Development

    2016-07-14

    The waste feed qualification program is being developed to protect the Hanford Tank Waste Treatment and Immobilization Plant (WTP) design, safety basis, and technical basis by assuring waste acceptance requirements are met for each staged waste feed campaign prior to transfer from the Tank Operations Contractor to the feed receipt vessels inside the Pretreatment Facility. The Waste Feed Qualification Program Plan describes the three components of waste feed qualification: 1. Demonstrate compliance with the waste acceptance criteria 2. Determine waste processability 3. Test unit operations at laboratory scale. The glass fabrication unit operation is the final step in the process demonstration portion of the waste feed qualification process. This unit operation generally consists of combining each of the waste feed streams (high-level waste (HLW) and low-activity waste (LAW)) with Glass Forming Chemicals (GFCs), fabricating glass coupons, performing chemical composition analysis before and after glass fabrication, measuring hydrogen generation rate either before or after glass former addition, measuring rheological properties before and after glass former addition, and visual observation of the resulting glass coupons. Critical aspects of this unit operation are mixing and sampling of the waste and melter feeds to ensure representative samples are obtained as well as ensuring the fabrication process for the glass coupon is adequate. Testing was performed using a range of simulants (LAW and HLW simulants), and these simulants were mixed with high and low bounding amounts of GFCs to evaluate the mixing, sampling, and glass preparation steps in shielded cells using laboratory techniques. The tests were performed with off-the-shelf equipment at the Savannah River National Laboratory (SRNL) that is similar to equipment used in the SRNL work during qualification of waste feed for the Defense Waste Processing Facility (DWPF) and other waste treatment facilities at the

  10. An analysis of the qualification criteria for small radioactive material shipping packages

    Energy Technology Data Exchange (ETDEWEB)

    McClure, J.D.

    1983-05-01

    The RAM package design certification process has two important elements, testing and acceptance. These terms sound very similar but they have specific meanings. Qualification testing in the context of this study is the imposition of simulated accident test conditions upon the candidate package design. (Normal transportation environments may also be included.) Following qualification testing, the acceptance criteria provide the performance levels which, if demonstrated, indicate the ability of the RAM package to sustain the severity of the qualification testing sequence and yet maintain specified levels of package integrity. This study has used Severities of Transportation Accidents as a data base to examine the regulatory test criteria which are required to be met by small packages containing Type B quantities of radioactive material (RAM). The basic findings indicate that the present regulatory test standards provide significantly higher levels of protection for the surface transportation modes (truck, rail) than for RAM packages shipped by aircraft. It should also be noted that various risk assessment studies have shown that the risk to the public due to severe transport accidents by surface and air transport modes is very low. A key element in this study was the quantification of the severity of the transportation accident environment and the severity of the present qualification test standards (called qualification test standards in this document) so that a direct comparison could be made between them to assess the effectiveness of the existing qualification test standards. The manner in which this was accomplished is described.

  11. Status of Functional Qualification System for Nuclear Valve Assembly in KIMM

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. H.; Park, T. J.; Kim, Y. J. [Korea Institute of Machinery and Materials, Daejeon (Korea, Republic of)

    2016-05-15

    In this paper, the status of the test facility, the basic concept of the ASME QME-1 test, and the future work are presented. The measured performance parameter, such as pressure, temperature, flow rate, thrust, stroke, and time, is used for the maintenance method and the evaluation of the aging and fatigue in the operating valve. In these days, the survival of the safety related valve in severe accident is important issue. In Korea Institute of Machinery and Materials (KIMM), the functional facility and related Quality Assure (QA) system are made. In addition, the qualification research was made for the functional test of the valve as ASME QME-1. The methodology is based on the ASME QME-1 1997. But the future work for the ASME QME-1 2007 was performed. In real situation, the engineering work is needed for the functional test of the nuclear valve in QA system. So the research work for the qualification is needed. The functional qualification of the valve in the nuclear power plant is performed in KIMM The development of the research and facility required in the functional qualification is in progress. Now the functional qualification is possible domestically, that was impossible in previous time due to the lack of qualification technology and facility.

  12. Selective accumulation of biotin in arterial chemoreceptors: requirement for carotid body exocytotic dopamine secretion.

    Science.gov (United States)

    Ortega-Sáenz, Patricia; Macías, David; Levitsky, Konstantin L; Rodríguez-Gómez, José A; González-Rodríguez, Patricia; Bonilla-Henao, Victoria; Arias-Mayenco, Ignacio; López-Barneo, José

    2016-12-15

    Biotin, a vitamin whose main role is as a coenzyme for carboxylases, accumulates at unusually large amounts within cells of the carotid body (CB). In biotin-deficient rats biotin rapidly disappears from the blood; however, it remains at relatively high levels in CB glomus cells. The CB contains high levels of mRNA for SLC5a6, a biotin transporter, and SLC19a3, a thiamine transporter regulated by biotin. Animals with biotin deficiency exhibit pronounced metabolic lactic acidosis. Remarkably, glomus cells from these animals have normal electrical and neurochemical properties. However, they show a marked decrease in the size of quantal dopaminergic secretory events. Inhibitors of the vesicular monoamine transporter 2 (VMAT2) mimic the effect of biotin deficiency. In biotin-deficient animals, VMAT2 protein expression decreases in parallel with biotin depletion in CB cells. These data suggest that dopamine transport and/or storage in small secretory granules in glomus cells depend on biotin. Biotin is a water-soluble vitamin required for the function of carboxylases as well as for the regulation of gene expression. Here, we report that biotin accumulates in unusually large amounts in cells of arterial chemoreceptors, carotid body (CB) and adrenal medulla (AM). We show in a biotin-deficient rat model that the vitamin rapidly disappears from the blood and other tissues (including the AM), while remaining at relatively high levels in the CB. We have also observed that, in comparison with other peripheral neural tissues, CB cells contain high levels of SLC5a6, a biotin transporter, and SLC19a3, a thiamine transporter regulated by biotin. Biotin-deficient rats show a syndrome characterized by marked weight loss, metabolic lactic acidosis, aciduria and accelerated breathing with normal responsiveness to hypoxia. Remarkably, CB cells from biotin-deficient animals have normal electrophysiological and neurochemical (ATP levels and catecholamine synthesis) properties; however

  13. Workshop on environmental qualification of electric equipment

    Energy Technology Data Exchange (ETDEWEB)

    Lofaro, R.; Gunther, W.; Villaran, M.; Lee, B.S.; Taylor, J. [comps.] [Brookhaven National Lab., Upton, NY (United States)

    1994-05-01

    Questions concerning the Environmental Qualification (EQ) of electrical equipment used in commercial nuclear power plants have recently become the subject of significant interest to the US Nuclear Regulatory Commission (NRC). Initial questions centered on whether compliance with the EQ requirements for older plants were adequate to support plant operation beyond 40 years. After subsequent investigation, the NRC Staff concluded that questions related to the differences in EQ requirements between older and newer plants constitute a potential generic issue which should be evaluated for backfit, independent of license renewal activities. EQ testing of electric cables was performed by Sandia National Laboratories (SNL) under contract to the NRC in support of license renewal activities. Results showed that some of the environmentally qualified cables either failed or exhibited marginal insulation resistance after a simulated plant life of 20 years during accident simulation. This indicated that the EQ process for some electric cables may be non-conservative. These results raised questions regarding the EQ process including the bases for conclusions about the qualified life of components based upon artificial aging prior to testing.

  14. QUALIFICATIONS FRAMEWORK DEVELOPMENT AND QUALIFICATIONS RATING IN THE LAND MANAGEMENT SPHERE

    Directory of Open Access Journals (Sweden)

    A. A. Myrasheva

    2014-01-01

    Full Text Available The aim of the research is to observe the existing approaches to qualifications framework development in the sphere of land management, cadastres and real estate management, as well as the qualifications framework adaptation to European system. The relevance of the issue is related to the specific professional and institutional problems facing Russian educational establishments engaged in personnel training in the given sphere. The authors demonstrate the qualifications framework development in the land management sector regarding it as a key mechanism of educational mobility and the router for knowledge acquisition and updates. The qualifications framework is referred to as a systematic and structured description of recognized qualifications. The accepted worldwide methodology of organizing the educational process and quality control system is given. The emphasis is on the need to comply the qualifications framework with the Russian State Educational Standards.

  15. Genomic selection needs to be carefully assessed to meet specific requirements in livestock breeding programs

    Directory of Open Access Journals (Sweden)

    Elisabeth eJonas

    2015-02-01

    Full Text Available Genomic selection is a promising development in agriculture, aiming improved production by exploiting molecular genetic markers to design novel breeding programs and to develop new markers-based models for genetic evaluation. It opens opportunities for research, as novel algorithms and lab methodologies are developed. Genomic selection can be applied in many breeds and species. Further research on the implementation of genomic selection in breeding programs is highly desirable not only for the common good, but also the private sector (breeding companies. It has been projected that this approach will improve selection routines, especially in species with long reproduction cycles, late or sex-limited or expensive trait recording and for complex traits. The task of integrating genomic selection into existing breeding programs is, however, not straightforward. Despite successful integration into breeding programs for dairy cattle, it has yet to be shown how much emphasis can be given to the genomic information and how much additional phenotypic information is needed from new selection candidates. Genomic selection is already part of future planning in many breeding companies of pigs and beef cattle among others, but further research is needed to fully estimate how effective the use of genomic information will be for the prediction of the performance of future breeding stock. Genomic prediction of production in crossbreeding and across-breed schemes, costs and choice of individuals for genotyping are reasons for a reluctance to fully rely on genomic information for selection decisions. Breeding objectives are highly dependent on the industry and the additional gain when using genomic information has to be considered carefully. This review synthesizes some of the suggested approaches in selected livestock species including cattle, pig, chicken and fish. It outlines tasks to help understanding possible consequences when applying genomic information in

  16. Genomic selection needs to be carefully assessed to meet specific requirements in livestock breeding programs

    Science.gov (United States)

    Jonas, Elisabeth; de Koning, Dirk-Jan

    2015-01-01

    Genomic selection is a promising development in agriculture, aiming improved production by exploiting molecular genetic markers to design novel breeding programs and to develop new markers-based models for genetic evaluation. It opens opportunities for research, as novel algorithms and lab methodologies are developed. Genomic selection can be applied in many breeds and species. Further research on the implementation of genomic selection (GS) in breeding programs is highly desirable not only for the common good, but also the private sector (breeding companies). It has been projected that this approach will improve selection routines, especially in species with long reproduction cycles, late or sex-limited or expensive trait recording and for complex traits. The task of integrating GS into existing breeding programs is, however, not straightforward. Despite successful integration into breeding programs for dairy cattle, it has yet to be shown how much emphasis can be given to the genomic information and how much additional phenotypic information is needed from new selection candidates. Genomic selection is already part of future planning in many breeding companies of pigs and beef cattle among others, but further research is needed to fully estimate how effective the use of genomic information will be for the prediction of the performance of future breeding stock. Genomic prediction of production in crossbreeding and across-breed schemes, costs and choice of individuals for genotyping are reasons for a reluctance to fully rely on genomic information for selection decisions. Breeding objectives are highly dependent on the industry and the additional gain when using genomic information has to be considered carefully. This review synthesizes some of the suggested approaches in selected livestock species including cattle, pig, chicken, and fish. It outlines tasks to help understanding possible consequences when applying genomic information in breeding scenarios. PMID

  17. AGR-2 Data Qualification Report for ATR Cycle 154B

    Energy Technology Data Exchange (ETDEWEB)

    Binh Pham; Jeff Einerson

    2014-01-01

    This report provides the data qualification status of Advanced Gas Reactor-2 (AGR-2) fuel irradiation experimental data from Advanced Test Reactor (ATR) Cycle 154B as recorded in the Nuclear Data Management and Analysis System (NDMAS). This is the last cycle of AGR-2 irradiation, as the test train was pulled from the ATR core during the outage portion of ATR Cycle 155A. The AGR-2 data streams addressed in this report include thermocouple (TC) temperatures, sweep gas data (flow rates including new Fission Product Monitoring (FPM) downstream flows from Fission Product Monitoring System (FPMS) detectors, pressure, and moisture content), and FPMS data (release rates and release-to-birth rate ratios [R/Bs]) for each of the six capsules in the AGR-2 experiment. The final data qualification status for these data streams is determined by a Data Review Committee (DRC) comprised of AGR technical leads, Sitewide Quality Assurance (QA), and NDMAS analysts. The Data Review Committee reviewed the data acquisition process, considered whether the data met the requirements for data collection as specified in QA-approved Very High Temperature Reactor (VHTR) data collection plans, examined the results of NDMAS data testing and statistical analyses, and confirmed the qualification status of the data as given in this report.

  18. Integrated Requirement Selection and Scheduling for the Release Planning of a Software Product

    NARCIS (Netherlands)

    Li, C.; Akkermans, J.M.; Brinkkemper, S.; Diepen, G.

    2007-01-01

    This paper investigates two integer linear programming models that integrate requirement scheduling into software release planning. The first model can schedule the development of the requirements for the new release exactly in time so that the project span is minimized and the resource and

  19. Secondary Waste Cast Stone Waste Form Qualification Testing Plan

    Energy Technology Data Exchange (ETDEWEB)

    Westsik, Joseph H.; Serne, R. Jeffrey

    2012-09-26

    The Hanford Tank Waste Treatment and Immobilization Plant (WTP) is being constructed to treat the 56 million gallons of radioactive waste stored in 177 underground tanks at the Hanford Site. The WTP includes a pretreatment facility to separate the wastes into high-level waste (HLW) and low-activity waste (LAW) fractions for vitrification and disposal. The LAW will be converted to glass for final disposal at the Integrated Disposal Facility (IDF). Cast Stone – a cementitious waste form, has been selected for solidification of this secondary waste stream after treatment in the ETF. The secondary-waste Cast Stone waste form must be acceptable for disposal in the IDF. This secondary waste Cast Stone waste form qualification testing plan outlines the testing of the waste form and immobilization process to demonstrate that the Cast Stone waste form can comply with the disposal requirements. Specifications for the secondary-waste Cast Stone waste form have not been established. For this testing plan, Cast Stone specifications are derived from specifications for the immobilized LAW glass in the WTP contract, the waste acceptance criteria for the IDF, and the waste acceptance criteria in the IDF Permit issued by the State of Washington. This testing plan outlines the testing needed to demonstrate that the waste form can comply with these waste form specifications and acceptance criteria. The testing program must also demonstrate that the immobilization process can be controlled to consistently provide an acceptable waste form product. This testing plan also outlines the testing needed to provide the technical basis for understanding the long-term performance of the waste form in the disposal environment. These waste form performance data are needed to support performance assessment analyses of the long-term environmental impact of the secondary-waste Cast Stone waste form in the IDF

  20. Attentional Requirements for the Selection of Words from Different Grammatical Categories

    Science.gov (United States)

    Ayora, Pauline; Janssen, Niels; Dell'Acqua, Roberto; Alario, F.-Xavier

    2009-01-01

    Two grammatical classes are commonly distinguished in psycholinguistic research. The open-class includes content words such as nouns, whereas the closed-class includes function words such as determiners. A standing issue is to identify whether these words are retrieved through similar or distinct selection mechanisms. We report a comparative…

  1. 78 FR 53963 - Final Priorities, Requirements, Definitions, and Selection Criteria; Race to the Top-Early...

    Science.gov (United States)

    2013-08-30

    ..., and Selection Criteria; Race to the Top--Early Learning Challenge AGENCY: Department of Education and... definition of Comprehensive Assessment System applies to the use of assessments in Early Learning and... address racially and economically diverse learning environments, the priorities, definitions, and...

  2. Qualification of Daiichi Units 1, 2, and 3 Data for Severe Accident Evaluations - Process and Illustrative Examples from Prior TMI-2 Evaluations

    Energy Technology Data Exchange (ETDEWEB)

    Rempe, Joy Lynn [Idaho National Lab. (INL), Idaho Falls, ID (United States); Knudson, Darrell Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    The accidents at the Three Mile Island Unit 2 (TMI-2) Pressurized Water Reactor (PWR) and the Daiichi Units 1, 2, and 3 Boiling Water Reactors (BWRs) provide unique opportunities to evaluate instrumentation exposed to severe accident conditions. Conditions associated with the release of coolant and the hydrogen burn that occurred during the TMI-2 accident exposed instrumentation to harsh conditions, including direct radiation, radioactive contamination, and high humidity with elevated temperatures and pressures. As part of a program initiated in 2012 by the Department of Energy Office of Nuclear Energy (DOE-NE), a review was completed to gain insights from prior TMI-2 sensor survivability and data qualification efforts. This initial review focused on the set of sensors deemed most important by post-TMI-2 instrumentation evaluation programs. Instrumentation evaluation programs focused on data required by TMI-2 operators to assess the condition of the reactor and containment and the effect of mitigating actions taken by these operators. In addition, prior efforts focused on sensors providing data required for subsequent forensic evaluations and accident simulations. To encourage the potential for similar activities to be completed for qualifying data from Daiichi Units 1, 2, and 3, this report provides additional details related to the formal process used to develop a qualified TMI-2 data base and presents data qualification details for three parameters: primary system pressure; containment building temperature; and containment pressure. As described within this report, sensor evaluations and data qualification required implementation of various processes, including comparisons with data from other sensors, analytical calculations, laboratory testing, and comparisons with sensors subjected to similar conditions in large-scale integral tests and with sensors that were similar in design to instruments easily removed from the TMI-2 plant for evaluations. As documented

  3. Army Officer Job Analysis: Identifying Performance Requirements to Inform Officer Selection and Assignment

    Science.gov (United States)

    2011-08-01

    Persistence of efforts Potential Predictor Measures Measures of achievement (e.g., SAT ) Education, Training, and Experience (e.g., college major...these domains, through standardized college entry exams such as the SAT and the ACT. As noted earlier, ARI is also conducting research to explore the...poor demand satisfaction. 3. Perform stockage level management Determine the RO and ROP. Select the appropriate Stockage List Code ( SLC

  4. Sophorolipids: improvement of the selective production by Starmerella bombicola through the design of nutritional requirements.

    Science.gov (United States)

    Ribeiro, Isabel A; Bronze, M Rosário; Castro, Matilde F; Ribeiro, Maria H L

    2013-03-01

    Microtiter plates were used as minireactors to study Starmerella bombicola growth and sophorolipid (SL) production. Compositional analysis of SL mixtures by liquid chromatography with electrospray ionization tandem mass spectrometry showed similar results on SLs produced using the laboratory scale (shake flask) and the microscale (24-well microtiter plates (MTP)) approach. MTP suitability on SL production was proven, being this approach, especially advantageous on SL screening. Several hydrophilic carbon sources, hydrophobic co-substrates and nitrogen sources were supplied to culture media, and their influence on SL production was evaluated. The selection of specific hydrophobic co-substrate and nitrogen sources influenced the ratio acidic/lactonic SLs. In fact, it was observed that the production of acidic C18:1 diacetylated hydroxy fatty acid SLs was favoured when culture media was supplied with avocado, argan, sweet almond and jojoba oil or when NaNO(3) was supplied instead of urea. This last case was observed after 144 h of cultivation. A new SL, lactonic C18:3 hydroxy fatty acid diacetylated SL, was detected when borage and onagra oils were used individually as co-substrates. Overall results indicated the potential of the selective production of different and new sophorolipids by Starmerella bombicola based on the selection of carbon and nitrogen sources to culture media.

  5. 77 FR 35953 - Arts in Education National Program; Final Priority, Requirements, Definitions, and Selection...

    Science.gov (United States)

    2012-06-15

    ... AGENCY: Office of Innovation and Improvement, Department of Education. ACTION: Notice. SUMMARY: The Assistant Deputy Secretary for Innovation and Improvement announces the final priority, requirements... importance of sequential, standards-based teaching that is unique to music education. The commenter added...

  6. 77 FR 12257 - Proposed Priorities, Requirements, Definitions, And Selection Criteria; Teacher Incentive Fund...

    Science.gov (United States)

    2012-02-29

    ... systems and tools that would enhance the quality and success of the PBCS, such as high-quality teacher..., master teacher or coach positions. Although both options require additional components to conform with... success and sustainability if the same systems are used to evaluate every educator within an LEA. In...

  7. Recruiting for Fitness: Qualifications and the Challenges of an Employer-Led System

    Science.gov (United States)

    Lloyd, Caroline

    2008-01-01

    Current UK skills policy is centred on the need to drive up qualification obtainment and make the system more employer-led with Sector Skills Councils (SSCs) being given the role of articulating the "voice" of employers. Through a study of recruitment and selection processes in the fitness industry, this paper explores employers'…

  8. NEMP Qualification of Electrically Simple Equipment on Aircraft via Analysis

    Science.gov (United States)

    Ockerse, J.; Flessa, C.

    2012-05-01

    The purpose of this paper is to demonstrate a theoretical analysis method for analysing the NEMP (Nuclear Electromagnetic Pulse) qualification status of electrically simple equipment or devices. (e.g., switches, actuators, sensors, etc.) The method is transparent to the certification authorities. This is in order to release them from the (costly) requirement for actual NEMP testing of these parts. This work is based on the experience gained in the successful certification of an advanced, all-carbon- fibre-composite (CFC) military helicopter. The method has been validated by testing.

  9. The Viking mortar - Design, development, and flight qualification.

    Science.gov (United States)

    Brecht, J. P.; Pleasants, J. E.; Mehring, R. D.

    1973-01-01

    Approximately 25,400 ft above the local surface of Mars, a radar height sensor fires the Viking mortar, which ejects a 53-ft D sub o disk-gap-band (DGB) parachute. The parachute decelerates and stabilizes the Viking lander sufficiently for the terminal engine system to take over and effect a soft landing. The general design and environmental requirements for the mortar system are presented; various illustrations of the mortar components and how the mortar system functions also are presented. Primary emphasis is placed on manufacturing, developing, and qualification testing of the mortar system.

  10. Type I interferon is selectively required by dendritic cells for immune rejection of tumors.

    OpenAIRE

    Diamond, Mark S.; Kinder, Michelle; Matsushita, Hirokazu; Mashayekhi, Mona; Dunn, Gavin P.; Archambault, Jessica M.; Lee, Hsiaoju; Arthur, Cora D.; White, J. Michael; Kalinke, Ulrich; Murphy, Kenneth M.; Schreiber, Robert D.

    2011-01-01

    Cancer immunoediting is the process whereby the immune system suppresses neoplastic growth and shapes tumor immunogenicity. We previously reported that type I interferon (IFN-α/β) plays a central role in this process and that hematopoietic cells represent critical targets of type I IFN's actions. However, the specific cells affected by IFN-α/β and the functional processes that type I IFN induces remain undefined. Herein, we show that type I IFN is required to initiate the antitumor response a...

  11. Complex sensorimotor transformation processes required for response selection are facilitated by the striatum.

    Science.gov (United States)

    Stock, Ann-Kathrin; Ness, Vanessa; Beste, Christian

    2015-12-01

    Both fronto-parietal networks and the basal ganglia play an important role in action cascading. It is well-known that cortical structures mediate sensorimotor transformation for this purpose. The striatum receives extensive input from those cortical structures and has been shown to be modulated by the predictability of cortical input. Until today, it has however remained unclear whether the processing of spatial codes or even sensorimotor transformation processes for the purpose of action cascading involve the striatum. We therefore examined this question by means of fMRI using a stop-change task that varied the predictability as well as the complexity of sensorimotor transformations required for correct responding in the context of action cascading. On the behavioral level, we found that the complexity of sensorimotor transformation processes only prolonged reaction times when the requirement for this transformation was predictable. fMRI results matched this effect showing enhanced activity of the caudate in case a complex sensorimotor transformation could be anticipated. Irrespective of the complexity of the required transformations, the putamen was furthermore involved in the prediction of imminent action cascading demands. Taken together, our findings give rise to a conceptual advance regarding basal ganglia function by showing that the anticipation and, more importantly, processing of complex sensorimotor transformation processes involves the striatum. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Ubc9 Is Required for Positive Selection and Late-Stage Maturation of Thymocytes.

    Science.gov (United States)

    Wang, Aibo; Ding, Xiao; Demarque, Maud; Liu, Xindong; Pan, Deng; Xin, Huawei; Zhong, Bo; Wang, Xiaohu; Dejean, Anne; Jin, Wei; Dong, Chen

    2017-05-01

    SUMOylation is an important posttranslational modification that regulates protein function in diverse biological processes. However, its role in early T cell development has not been genetically studied. UBC9 is the only E2 enzyme for all SUMOylation. In this study, by selectively deleting Ubc9 gene in T cells, we have investigated the functional roles of SUMOylation in T cell development. Loss of Ubc9 results in a significant reduction of CD4 and CD8 single-positive lymphocytes in both thymus and periphery. Ubc9-deficient cells exhibit defective late-stage maturation post the initial positive selection with increased apoptosis and impaired proliferation, among which attenuated IL-7 signaling was correlated with the decreased survival of Ubc9-deficent CD8 single-positive cells. Furthermore, NFAT nuclear retention induced by TCR signals was regulated by SUMOylation during thymocytes development. Our study thus reveals a novel posttranslational mechanism underlying T cell development. Copyright © 2017 by The American Association of Immunologists, Inc.

  13. Beyond EICA: understanding post-establishment evolution requires a broader evaluation of potential selection pressures

    Directory of Open Access Journals (Sweden)

    Joshua Atwood

    2011-10-01

    Full Text Available Research on post-establishment evolution in nonnative plant populations has focused almost exclusively on testing the Evolution of Increased Competitive Ability (EICA hypothesis, which posits that the lack of specialized herbivores in the invaded range drives evolution in nonnative plant populations. Fifteen years of conflicting EICA test results suggest that selection pressures other than specialized herbivory are important in driving post-establishment evolution in invasive species. Alternative hypotheses, such as the Evolution of Reduced Competitive Ability (ERCA hypothesis, have been proposed but have received little attention or testing. We argue that the lack of consensus across studies that test EICA may be due in part to the lack of consistent definitions and varying experimental design parameters, and that future research in this field would benefit from new methodological considerations. We examined previous work evaluating post-establishment evolution and evaluated the range of study systems and design parameters used in testing the EICA hypothesis. Our goal was to identify where different uses of ecological terms and different study parameters have hindered consensus and to suggest a path forward to move beyond EICA in post-establishment evolution studies. We incorporated these methods into a design framework that will increase data harmony across future studies and will facilitate examinations of any potential selection pressure driving evolution in the invaded range.

  14. Selection is not required to produce invariant T-cell receptor gamma-gene junctional sequences.

    Science.gov (United States)

    Asarnow, D M; Cado, D; Raulet, D H

    1993-03-11

    Recombination of V-, D- and J-gene segments can generate an enormous diversity of T-cell antigen receptor (TCR) gene sequences. Although many gamma delta T cells fully exploit this diversification process, those in the epidermal and vaginal epithelium do not, predominantly expressing invariant gamma delta receptors in which the V-(D)-J junctional sequences in almost all the productive rearrangements are identical. The almost exclusive use of identical TCRs by cells in these sites is thought to reflect recognition of a stress-induced autologous antigen. To explain the prevalence of the invariant junctional sequences, it has been proposed that thymic selection operates on a population of originally diverse progenitor cells, resulting in a homogeneous repertoire. Alternatively the invariant sequences may result from biases in the recombination machinery in the fetal thymic progenitors of these cells. We report here the use of mice into which mutated TCR gamma-gene rearrangement substrates have been introduced as transgenes to demonstrate directly that the canonical TCR V gamma 3-J gamma 1 and V gamma 4-J gamma 1 sequences occur at high frequency in the absence of the possibility of selection for the protein products.

  15. Mechanical design and qualification of IR filter mounts and filter wheel of INSAT-3D sounder for low temperature

    Science.gov (United States)

    Vora, A. P.; Rami, J. B.; Hait, A. K.; Dewan, C. P.; Subrahmanyam, D.; Kirankumar, A. S.

    2017-11-01

    Next generation Indian Meteorological Satellite will carry Sounder instrument having subsystem of filter wheel measuring Ø260mm and carrying 18 filters arranged in three concentric rings. These filters made from Germanium, are used to separate spectral channels in IR band. Filter wheel is required to be cooled to 214K and rotated at 600 rpm. This Paper discusses the challenges faced in mechanical design of the filter wheel, mainly filter mount design to protect brittle germanium filters from failure under stresses due to very low temperature, compactness of the wheel and casings for improved thermal efficiency, survival under vibration loads and material selection to keep it lighter in weight. Properties of Titanium, Kovar, Invar and Aluminium materials are considered for design. The mount has been designed to accommodate both thermal and dynamic loadings without introducing significant aberrations into the optics or incurring permanent alignment shifts. Detailed finite element analysis of mounts was carried out for stress verification. Results of the qualification tests are discussed for given temperature range of 100K and vibration loads of 12g in Sine and 11.8grms in Random at mount level. Results of the filter wheel qualification as mounted in Electro Optics Module (EOM) are also presented.

  16. Striatal fast-spiking interneurons selectively modulate circuit output and are required for habitual behavior

    Science.gov (United States)

    O'Hare, Justin K; Li, Haofang; Kim, Namsoo; Gaidis, Erin; Ade, Kristen; Beck, Jeff; Yin, Henry

    2017-01-01

    Habit formation is a behavioral adaptation that automates routine actions. Habitual behavior correlates with broad reconfigurations of dorsolateral striatal (DLS) circuit properties that increase gain and shift pathway timing. The mechanism(s) for these circuit adaptations are unknown and could be responsible for habitual behavior. Here we find that a single class of interneuron, fast-spiking interneurons (FSIs), modulates all of these habit-predictive properties. Consistent with a role in habits, FSIs are more excitable in habitual mice compared to goal-directed and acute chemogenetic inhibition of FSIs in DLS prevents the expression of habitual lever pressing. In vivo recordings further reveal a previously unappreciated selective modulation of SPNs based on their firing patterns; FSIs inhibit most SPNs but paradoxically promote the activity of a subset displaying high fractions of gamma-frequency spiking. These results establish a microcircuit mechanism for habits and provide a new example of how interneurons mediate experience-dependent behavior. PMID:28871960

  17. SELECTED REQUIREMENTS OF INTEGRATED MANAGEMENT SYSTEMS BASED ON PAS 99 SPECIFICATION

    Directory of Open Access Journals (Sweden)

    Paweł Nowicki

    2013-03-01

    Full Text Available The aim this research was to analyze the ways of integration of management systems in food sector. The study involved the documentation, audits, corrective and preventive actions and management's review phases described in the specification PAS 99, which is one of common elements of integrated management systems. Four organizations were selected for the study. The organizations had introduced and certified at least two standardized management systems. It was assumed that the investigated organizations should have implemented the HACCP system. Studies were conducted as a case study. The employees responsible for the functioning of management systems were interviewed in all four organizations. The study was conducted in the form of in-depth interviews based on pre-prepared script. The scenario was developed based on the PAS 99 guideline. The process of integration of management systems implemented in the studied companies reveals the full compliance of an integrated management system with PASS 99 in the policy area.

  18. Global Trend In The Qualifications Of Medical Educators | Issa ...

    African Journals Online (AJOL)

    NPMCN) or its equivalents is the highest educational and professional qualification of clinical Medical Educators in Nigeria while PhD is the acceptable highest qualification for their basic medical sciences counterparts. This had been the status ...

  19. Is selection required for the accumulation of somatic mitochondrial DNA mutations in post-mitotic cells?

    Science.gov (United States)

    Durham, S E; Samuels, D C; Chinnery, P F

    2006-06-01

    Mitochondrial DNA (mtDNA) mutations accumulate in the skeletal muscle of patients with mtDNA disease, and also as part of healthy ageing. Simulations of human muscle fibres suggest that, over many decades, the continuous destruction and copying of mtDNA (relaxed replication) can lead to dramatic changes in the percentage level of mutant mtDNA in non-dividing cells through random genetic drift. This process should apply to both pathogenic and neutral mutations. To test this hypothesis we sequenced the entire mitochondrial genome for 20 muscle fibres from a healthy elderly 85-year-old individual, chosen because of the low frequency of cytochrome c oxidase negative fibres. Phenotypically neutral single base substitutions were detected in 15% of the healthy fibres, supporting the hypothesis that positive selection is not essential for the clonal expansion of mtDNA point mutations during human life. Treatments that enhance mtDNA replication, such as vigorous excercise, could amplify this process, with potentially detrimental long-term consequences.

  20. CLASSIFICATION OF SPECIALTIES AND QUALIFICATIONS IN REPUBLIC OF BELARUS: TENDENCIES AND PROSPECTS

    Directory of Open Access Journals (Sweden)

    O. A. Oleks

    2016-01-01

    Full Text Available In the present publication short data on the system of specialties and qualifications functioning in Republic of Belarus, her features, scope of application are given. The purpose and problems of the revision of the National classifier of the Republic of Belarus «Specialties and qualifications», its orientation to reduce the gap between the content of education and content of activity of graduates of establishments of education are described. The main tendencies of change of the operating classification – on the basis of types of economic activity and international standard classification of education taking into account requirements of employers, minimization of economic expenses for education, including due to minimization of classification units, rapprochement of positions with educational systems of other states are revealed. Prospects of development of national system of specialties and qualifications are disclosed. Tendencies and prospects of the expected changes are shown on the examples of the certain specialties offered by BNTU (Belarusian National Technical University.

  1. THE CONTENT OF QUALIFICATION OF CRIMES

    Directory of Open Access Journals (Sweden)

    Vasiliy Veklenko

    2017-01-01

    Full Text Available УДК 343(2+7The main provisions of the theory of qualification of crimes were developed in the Soviet times. Some of them, notably relating to the content of criminal law assessment, have become obsolete. Therefore, the article aims to interpret a new vision of the content of qualification. The methods used in the research include analysis, synthesis, induction, deduction, interview and statistical method. The authors note that in practice, in fact, general and specific signs of the crimes appearing in the criminal law are used in the qualification of crime.The authors question the use of "corpus delicti" in enforcement during the criminal legal evaluation. Corpus delicti was created in science to the full understanding and disclosure of the crime and its possible structures. It is impossible to carry out qualification and to resolve issues of criminal responsibility or exemption from it on the basis of scientific statements, which are not enshrined in law.Without knowledge of corpus delicti it is possible to hold a formal qualification of the offences and the imposition of criminal liability. This is due to the fact that all penal signs, sufficient for criminal liability provided for in the existing criminal law of the Russian Federation.The authors make the conclusion that qualification is carried out not in terms of corpus delicti, which is a scientific category, but on the basis of general features of crime – guilt, social danger, unlawfulness, liability to punishment, since it is them that are consolidated on the legislative level.

  2. 14 CFR Appendix C to Part 60 - Qualification Performance Standards for Helicopter Full Flight Simulators

    Science.gov (United States)

    2010-01-01

    ... required for aircraft certification and simulation programming and validation (b) For each maneuver or... to the FAA's Aircraft Certification Service. b. The data, regardless of source, must be presented: (1... operation of the aircraft and the operation of the FFS. e. The NSPM will conduct continuing qualification...

  3. 14 CFR Appendix B to Part 60 - Qualification Performance Standards for Airplane Flight Training Devices

    Science.gov (United States)

    2010-01-01

    ... required for aircraft certification and simulation programming and validation. (b) For each maneuver or... appropriate data reduction and analysis methods and techniques, acceptable to the FAA's Aircraft Certification... physically replicate the aircraft in control operation. End Information 25. FTD Qualification on the Basis of...

  4. Accounting Professor Qualification in Digital Age: A Perception Study on Brazilian Professors

    Science.gov (United States)

    Vendruscolo, Maria Ivanice; Behar, Patrícia Alejandra

    2015-01-01

    This papers aims at analyzing the perception of Accounting professors about the necessary qualifications in Accounting undergraduate courses. The contribution of this study is to theoretically discuss the education of Accounting professors, with empirical data, because Accounting teaching requires specific competencies in the digital area. The…

  5. Nuclear Technology. Course 28: Welding Inspection. Module 28-5, Qualifications.

    Science.gov (United States)

    Espy, John

    This fifth in a series of ten modules for a course titled Welding Inspection describes qualification requirements for welding procedures and welders and the role of the nuclear quality assurance/quality control technician. The module follows a typical format that includes the following sections: (1) introduction, (2) module prerequisites, (3)…

  6. Space Technology-5 Lithium-Ion Battery Design, Qualification and Integration and Testing

    Science.gov (United States)

    Rao, Gopalakishna M.; Stewart, Karen; Ameen, Syed; Banfield, Peter K.

    2005-01-01

    This document is a viewgraph presentation that reviews the Lithium Ion Battery for the Space Technology-5 (ST-5) mission. Included in the document is a review of the ST-5 Mission, a review of the battery requirements, a description of the battery and the battery materials. The testing and the integration and qualification data is reviewed.

  7. Improved CYP3A4 Molecular Models Accurately Predict Phe215 Requirement for Raloxifene Dehydrogenation Selectivity

    Science.gov (United States)

    Moore, Chad D.; Shahrokh, Kiumars; Sontum, Stephen F.; Cheatham, Thomas E.; Yost, Garold S.

    2010-01-01

    The use of molecular modeling in conjunction with site-directed mutagenesis has extensively been used to study substrate orientation within cytochrome P450 active sites, and to identify potential residues involved in positioning and catalytic mechanisms of these substrates. However, because docking studies utilize static models to simulate dynamic P450 enzymes, the effectiveness of these studies are highly dependent on accurate enzyme models. This study employed a cytochrome P450 3A4 (CYP3A4) crystal structure (PDB code:1W0E) to predict the sites of metabolism of the known CYP3A4 substrate raloxifene. In addition, partial charges were incorporated into the P450 heme moiety to investigate the effect of the modified CYP3A4 model on metabolite prediction with the ligand-docking program Autodock. Dehydrogenation of raloxifene to an electrophilic di-quinone methide intermediate has been linked to the potent inactivation of CYP3A4. Active site residues involved in the positioning and/or catalysis of raloxifene supporting dehydrogenation were identified with the two models, and site-directed mutagenesis studies were conducted to validate the models. The addition of partial charges to the heme moiety increased accuracy of the docking studies, increasing the number of conformations predicting dehydrogenation, and facilitating the identification of substrate/active site residue interactions. Based on the improved model, the Phe215 residue was hypothesized to play an important role in orienting raloxifene for dehydrogenation through a combination of electrostatic and steric interactions. Substitution of this residue with glycine or glutamine significantly decreased dehydrogenation rates without concurrent changes in the rates of raloxifene oxygenation. Thus, the improved structural model predicted novel enzyme/substrate interactions that control the selective dehydrogenation of raloxifene to its protein-binding intermediate. PMID:20812728

  8. Adverse Selection in China's Home Mortgage Policy

    DEFF Research Database (Denmark)

    Gao, Cixiu

    2016-01-01

    The Chinese home buyers are liquidity constrained with limited access to refinance, dissatisfactory social insurance and high home prices. The government requires all borrowers to make a substantial down payment, normally 20% to 50% of the home price, depending on non-risk-related qualifications....... vulnerable to negative shocks. The model is estimated using individual mortgage data provided by a major commercial bank of southeast China. We then provide forecasts on long-run default probabilities, as well as quantitative evidence for future adverse selection....

  9. Gluing interface qualification test results and gluing process development of the EUCLID near-infrared spectro-photometer optical assembly

    Science.gov (United States)

    Mottaghibonab, A.; Thiele, H.; Gubbini, E.; Dubowy, M.; Gal, C.; Mecsaci, A.; Gawlik, K.; Vongehr, M.; Grupp, F.; Penka, D.; Wimmer, C.; Bender, R.

    2016-07-01

    The Near Infrared Spectro-Photometer Optical assembly (NIOA) of EUCLID satellite requires high precision large lens holders with different lens materials, shapes and diameters. The aspherical lenses are glued into their separate CTE matched lens holder. The gluing of the lenses in their holder with 2K epoxy is selected as bonding process to minimize the stress in the lenses to achieve the required surface form error (SFE) performance (32nm) and lens position stability (+/-10μm) due to glue shrinkage. Adhesive shrinkage stress occurs during the glue curing at room temperature and operation in cryogenic temperatures, which might overstress the lens, cause performance loss, lens breakage or failure of the gluing interface. The selection of the suitable glue and required bonding parameters, design and qualification of the gluing interface, development and verification of the gluing process was a great challenge because of the low TRL and heritage of the bonding technology. The different material combinations (CaF2 to SS316L, LF5G15 and S-FTM16 to Titanium, SUPRASIL3001 to Invar M93), large diameter (168mm) and thin edge of the lenses, cryogenic nonoperational temperature (100K) and high performance accuracy of the lenses were the main design driver of the development. The different coefficients of thermal expansion (CTE) between lens and lens holder produce large local mechanical stress. As hygroscopic crystal calcium fluoride (CaF2) is very sensitive to moisture therefore an additional surface treatment of the gluing area is necessary. Extensive tests e.g glue handling and single lap shear tests are performed to select the suitable adhesive. Interface connection tests are performed to verify the feasibility of selected design (double pad design), injection channel, the roughness and treatment of the metal and lens interfaces, glue thickness, glue pad diameter and the gluing process. CTE and dynamic measurements of the glue, thermal cycling, damp- heat, connection

  10. Impact of the Europeanisation of Education: Qualifications Frameworks in Europe

    Science.gov (United States)

    Mikulec, Borut

    2017-01-01

    This article examines the influence of the European qualifications framework--a key European lifelong learning policy instrument for improving employability, comparability and mobility in the European educational space--on the establishment of national qualifications frameworks in Europe. The European qualifications framework and national…

  11. 14 CFR 121.915 - Continuing qualification curriculum.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Continuing qualification curriculum. 121... Continuing qualification curriculum. Each continuing qualification curriculum must contain training and... training device as approved in the certificate holder's curriculum that must be completed during each...

  12. 28 CFR 50.24 - Annuity broker minimum qualifications.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Annuity broker minimum qualifications. 50....24 Annuity broker minimum qualifications. (a) Minimum standards. The Civil Division, United States Department of Justice, shall establish a list of annuity brokers who meet minimum qualifications for...

  13. Space qualification of high capacity grooved heat pipes

    Energy Technology Data Exchange (ETDEWEB)

    Dubois, M.; Mullender, B.; Druart, J. [SABCA, Societe Anomyme Belgel de Construction Aeronautique (Belgium); Supper, W.; Beddows, A. [ESTEC-The (Netherlands)

    1996-12-31

    Based on the thermal requirements of the future telecommunication satellites, the development of a High Capacity Grooved Heat Pipe (HPG), was contracted by ESA to SABCA leading to an aluminium extruded heat pipe (outer diameter of 25 mm) based on a multi re-entrant grooves design. After an intensive acceptance test campaign whose results showed a good confidence in the design and the fulfillment of the required specifications of heat transport and on tilt capability (experimental maximum heat transport capability of 1500 Watt metres for a vapour temperature of 20 deg C), similar heat pipes have been developed with various outer diameters (11 mm, 15 mm and 20 mm) and with various shapes (circular outer shapes, integrated saddles). Several of these heat pipes were tested during two parabolic flight campaigns, by varying the heat loads during the micro-gravity periods. This HGP heat pipe family is now being submitted to a space qualification program according to ESA standards (ESA PSS-49), both in straight and bent configuration. Within this qualification, the heat pipes are submitted to an extended test campaign including environmental (random/sinus vibration, constant acceleration) and thermal tests (thermal performance, thermal cycle, thermal soak, ageing). (authors) 9 refs.

  14. 15 CFR 40.2 - Qualifications.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Qualifications. 40.2 Section 40.2 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade BUREAU OF THE CENSUS, DEPARTMENT OF COMMERCE TRAINING OF FOREIGN PARTICIPANTS IN CENSUS PROCEDURES AND GENERAL STATISTICS § 40.2...

  15. 9 CFR 2.32 - Personnel qualifications.

    Science.gov (United States)

    2010-01-01

    ... least the following areas: (1) Humane methods of animal maintenance and experimentation, including: (i... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Personnel qualifications. 2.32 Section 2.32 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF...

  16. STEM Leadership Qualification: Tomorrow's Leaders Today

    Science.gov (United States)

    Williams, Chris

    2009-01-01

    This article features the Science, Technology, Engineering and Mathematics (STEM) Leadership Qualification programme, developed by the Centre for Science Education (CSE) at Sheffield Hallam University in collaboration with Edexcel, which sets out to develop leadership skills and capabilities through contexts in STEM. With six units to complete…

  17. Education, Economic Globalisation and National Qualifications Frameworks

    Science.gov (United States)

    Lauder, Hugh

    2011-01-01

    There are many aims that have been articulated with respect to national qualifications frameworks (NQFs). Among them are those concerned with transparency, which is to say, that it is assumed that once employers understand the competencies of employees, as defined by their education credentials, then the mismatch between what employers are looking…

  18. Development Of A Macro-Batch Qualification Strategy For The Hanford Tank Waste Treatment And Immobilization Plant

    Energy Technology Data Exchange (ETDEWEB)

    Herman, Connie C.

    2013-09-30

    The Savannah River National Laboratory (SRNL) has evaluated the existing waste feed qualification strategy for the Hanford Tank Waste Treatment and Immobilization Plant (WTP) based on experience from the Savannah River Site (SRS) Defense Waste Processing Facility (DWPF) waste qualification program. The current waste qualification programs for each of the sites are discussed in the report to provide a baseline for comparison. Recommendations on strategies are then provided that could be implemented at Hanford based on the successful Macrobatch qualification strategy utilized at SRS to reduce the risk of processing upsets or the production of a staged waste campaign that does not meet the processing requirements of the WTP. Considerations included the baseline WTP process, as well as options involving Direct High Level Waste (HLW) and Low Activity Waste (LAW) processing, and the potential use of a Tank Waste Characterization and Staging Facility (TWCSF). The main objectives of the Hanford waste feed qualification program are to demonstrate compliance with the Waste Acceptance Criteria (WAC), determine waste processability, and demonstrate unit operations at a laboratory scale. Risks to acceptability and successful implementation of this program, as compared to the DWPF Macro-Batch qualification strategy, include: Limitations of mixing/blending capability of the Hanford Tank Farm; The complexity of unit operations (i.e., multiple chemical and mechanical separations processes) involved in the WTP pretreatment qualification process; The need to account for effects of blending of LAW and HLW streams, as well as a recycle stream, within the PT unit operations; and The reliance on only a single set of unit operations demonstrations with the radioactive qualification sample. This later limitation is further complicated because of the 180-day completion requirement for all of the necessary waste feed qualification steps. The primary recommendations/changes include the

  19. Round table discussion " Development of qualification framework in meteorology (TEMPUS QUALIMET)"

    Science.gov (United States)

    Bashmakova, I.; Belotserkovsky, A.; Karlin, L.; Petrosyan, A.; Serditova, N.; Zilitinkevich, S.

    2010-09-01

    The international consortium has started implementing a project aimed at the development of unified framework of qualifications in meteorology (QualiMet), setting a system of recognition and award of qualifications up to Doctoral level based on standards of knowledge, skill and competence acquired by learners is underway. The QualiMet has the following specific objectives: 1. To develop standards of knowledge, skills and competence for all qualifications up to Doctoral level needed in all possible occupations meteorology learner can undertake, by July 2011 2. To develop reciprocally recognized rubrics, criteria, methods and tools for assessing the compliance with the developed standards (quality assurance), by July 2012 3. To set the network of Centers of Excellence as the primary designer of sample education programs and learning experiences, both in brick-and-mortar and distant setting of delivery, leading to achievement of the developed standards, by December 2012 4. To set a system of mutual international recognition and award of qualifications in meteorology based on the developed procedures and establishment of self-regulatory public organization, by December 2012 The main beneficiaries of the project are: 1. Meteorology learners from the consortium countries. They will be able to make informed decisions about available qualification choices and progression options and provided an opportunity for students and graduates to participate in the system of international continuous education. 2. Meteorology employers from the consortium countries, They will be able to specify the level of knowledge, skill and competence required for occupational roles, evaluate qualifications presented, connect training and development with business needs. 3. Students and academic staff of all the consortium members, who will gain the increased mobility and exchange the fluxes of culturally and institutionally diversified lecturers and qualified specialists

  20. Code qualification of structural materials for AFCI advanced recycling reactors.

    Energy Technology Data Exchange (ETDEWEB)

    Natesan, K.; Li, M.; Majumdar, S.; Nanstad, R.K.; Sham, T.-L. (Nuclear Engineering Division); (ORNL)

    2012-05-31

    This report summarizes the further findings from the assessments of current status and future needs in code qualification and licensing of reference structural materials and new advanced alloys for advanced recycling reactors (ARRs) in support of Advanced Fuel Cycle Initiative (AFCI). The work is a combined effort between Argonne National Laboratory (ANL) and Oak Ridge National Laboratory (ORNL) with ANL as the technical lead, as part of Advanced Structural Materials Program for AFCI Reactor Campaign. The report is the second deliverable in FY08 (M505011401) under the work package 'Advanced Materials Code Qualification'. The overall objective of the Advanced Materials Code Qualification project is to evaluate key requirements for the ASME Code qualification and the Nuclear Regulatory Commission (NRC) approval of structural materials in support of the design and licensing of the ARR. Advanced materials are a critical element in the development of sodium reactor technologies. Enhanced materials performance not only improves safety margins and provides design flexibility, but also is essential for the economics of future advanced sodium reactors. Code qualification and licensing of advanced materials are prominent needs for developing and implementing advanced sodium reactor technologies. Nuclear structural component design in the U.S. must comply with the ASME Boiler and Pressure Vessel Code Section III (Rules for Construction of Nuclear Facility Components) and the NRC grants the operational license. As the ARR will operate at higher temperatures than the current light water reactors (LWRs), the design of elevated-temperature components must comply with ASME Subsection NH (Class 1 Components in Elevated Temperature Service). However, the NRC has not approved the use of Subsection NH for reactor components, and this puts additional burdens on materials qualification of the ARR. In the past licensing review for the Clinch River Breeder Reactor Project (CRBRP

  1. First qualification of ITER Toroidal Field Coil conductor jacketing

    Energy Technology Data Exchange (ETDEWEB)

    Hamada, Kazuya, E-mail: hamada.kazuya@jaea.go.jp [Japan Atomic Energy Agency (Japan); Takahashi, Yoshikazu; Isono, Takaaki; Nunoya, Yoshihiko; Matsui, Kunihiro; Kawano, Katsumi; Oshikiri, Masayuki; Tsutsumi, Fumiaki; Koizumi, Norikiyo; Nakajima, Hideo; Okuno, Kiyoshi [Japan Atomic Energy Agency (Japan); Matsuda, Hidemitsu; Yano, Yoshitaka [Nippon Steel Engineering Co. Ltd (Japan); Devred, Arnauld; Bessette, Denis [ITER Organization (France)

    2011-10-15

    The Japan Atomic Energy Agency (JAEA) has the responsibility to procure 25% of the ITER Toroidal Field Coil conductors as the Japanese Domestic Agency (JADA) in the ITER project. The TF conductor is a circular shaped, cable-in-conduit conductor, composed of a cable and a stainless steel conduit (jacket). The outer diameter and maximum length of the TF conductor are 43.7 mm and 760 m, respectively. JAEA started to produce strand, cables and jacket sections and to construct a conductor manufacturing (jacketing) facility in 2008. Following preparation in December 2009 of the jacketing facility, the dummy cable, the jacket sections and fabrication procedures, such as welding, cable insertion, compaction and spooling, JAEA manufactured a 760 m long Cu dummy conductor for process qualification. Into the 760 m long Cu dummy conductor jacketing, JAEA successfully inserted the cable with a maximum force of 32 kN. The outer diameter of the cross section of the spooled conductor was 43.7 {+-} 0.15 mm, which complies with the ITER target requirement of 43.7 {+-} 0.3 mm. Following qualification of all manufacturing processes, JAEA has started to fabricate superconducting conductors for the TF coils.

  2. Teacher qualification and the achievement gap in early primary grades.

    Directory of Open Access Journals (Sweden)

    Donald Easton-Brooks

    2009-08-01

    Full Text Available Title I of the No Child Left Behind Act (P.L. 107-110, 115 Stat. 1245, 2002 holds schools accountable for reducing the academic achievement gap between the different ethnic groups and requires elementary school teachers to have at least a bachelors degree and a state certification. The purpose of this study was to examine the relationship of the qualification requirement of NCLB to the goal of reducing the academic achievement gap. The study found that students with a certified teacher for most of their early school experience scored higher in reading than students who did not have a certified teacher. In addition, certification was associated with slightly narrowing the academic gap between African American and European American students across early elementary grades.

  3. Affordable Development and Qualification Strategy for Nuclear Thermal Propulsion

    Science.gov (United States)

    Gerrish, Harold P., Jr.; Doughty, Glen E.; Bhattacharyya, Samit K.

    2013-01-01

    Nuclear Thermal Propulsion (NTP) is a concept which uses a nuclear reactor to heat a propellant to high temperatures without combustion and can achieve significantly greater specific impulse than chemical engines. NTP has been considered many times for human and cargo missions beyond low earth orbit. A lot of development and technical maturation of NTP components took place during the Rover/NERVA program of the 60's and early 70's. Other NTP programs and studies followed attempting to further mature the NTP concept and identify a champion customer willing to devote the funds and support the development schedule to a demonstration mission. Budgetary constraints require the use of an affordable development and qualification strategy that takes into account all the previous work performed on NTP to construct an existing database, and include lessons learned and past guidelines followed. Current guidelines and standards NASA uses for human rating chemical rocket engines is referenced. The long lead items for NTP development involve the fuel elements of the reactor and ground testing the engine system, subsystem, and components. Other considerations which greatly impact the development plans includes the National Space Policy, National Environmental Policy Act, Presidential Directive/National Security Council Memorandum #25 (Scientific or Technological Experiments with Possible Large-Scale Adverse Environmental Effects and Launch of Nuclear Systems into Space), and Safeguards and Security. Ground testing will utilize non-nuclear test capabilities to help down select components and subsystems before testing in a nuclear environment to save time and cost. Existing test facilities with minor modifications will be considered to the maximum extent practical. New facilities will be designed to meet minimum requirements. Engine and test facility requirements are based on the driving mission requirements with added factors of safety for better assurance and reliability

  4. 21 CFR 111.12 - What personnel qualification requirements apply?

    Science.gov (United States)

    2010-04-01

    ... dietary supplements. (b) You must identify who is responsible for your quality control operations. Each person who is identified to perform quality control operations must be qualified to do so and have... manufacturing, packaging, labeling, or holding, or in performing any quality control operations, must have the...

  5. 46 CFR 402.210 - Requirements and qualifications for registration.

    Science.gov (United States)

    2010-10-01

    ... the applicant's or Registered Pilot's visual acuity, color sense, physical condition, and competency... impairment to hearing or visual acuity, such as epilepsy, insanity, senility, acute venereal disease... original registration must have a visual acuity either with or without glasses of at least 20/20 vision in...

  6. ActRIIA and BMPRII Type II BMP receptor subunits selectively required for Smad4-independent BMP7-evoked chemotaxis.

    Directory of Open Access Journals (Sweden)

    Jeanette C Perron

    2009-12-01

    Full Text Available Bone morphogenetic protein (BMP-evoked reorientation and chemotaxis of cells occurs with rapid onset and involves events local to the cell membrane. The signaling pathways underlying these rapid processes likely diverge from those mediating classical transcriptional responses to BMPs but it remains unclear how BMP receptors are utilized to generate distinct intracellular mechanisms. We show that BMP7-evoked chemotaxis of monocytic cells depends on the activity of canonical type II BMP receptors. Although the three canonical type II BMP receptors are expressed in monocytic cells, inhibition of receptor subunit expression by RNAi reveals that ActRIIA and BMPRII, but not ActRIIB, are each essential for BMP7-evoked chemotaxis but not required individually for BMP-mediated induction. Furthermore, the chemotactic response to BMP7 does not involve canonical Smad4-dependent signaling but acts through PI3K-dependent signaling, illustrating selective activation of distinct intracellular events through differential engagement of receptors. We suggest a model of a BMP receptor complex in which the coordinated activity of ActRIIA and BMPRII receptor subunits selectively mediates the chemotactic response to BMP7.

  7. Development of nuclear equipment qualification technology

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Heon O; Kim, Wu Hyun; Kim, Jin Wuk; Kim, Jeong Hyun; Lee, Jeong Kyu; Kim, Yong Han; Jeong, Hang Keun [Korea Institute of Machinery and Materials, Taejon (Korea)

    1999-03-01

    In order to enhance testing and evaluation technologies, which is one of the main works of the Chanwon branch of KIMM(Korea Institute of Machinery and Materials), in addition to the present work scope of the testing and evaluation in the industrial facilities such as petroleum and chemical, plants, the qualification technologies of the equipments important to safety used in the key industrial facilities such as nuclear power plants should be localized: Equipments for testing and evaluation is to be set up and the related technologies must be developed. In the first year of this study, of vibration aging qualification technologies of equipments important to safety used in nuclear power plants have been performed. (author). 27 refs., 81 figs., 17 tabs.

  8. New Zealand's Move to Graduate-Profile Framed Qualifications: Implications, Challenges and the Occupational Identity Solution

    Science.gov (United States)

    Chan, Selena

    2016-01-01

    In 2008, the New Zealand Qualifications Authority (NZQA), responsible for the quality assurance of all qualifications, embarked on a review of all qualifications between Levels 1 and 6 on the 10-level National Qualifications Framework (NQF). The review process mandated the reviewed qualifications to be founded on outcome statements of graduate…

  9. Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement.

    Science.gov (United States)

    Dahan, Rony; Barnhart, Bryan C; Li, Fubin; Yamniuk, Aaron P; Korman, Alan J; Ravetch, Jeffrey V

    2016-06-13

    While engagement of the inhibitory Fcγ-receptor (FcγR) IIB is an absolute requirement for in vivo antitumor activity of agonistic mouse anti-CD40 monoclonal antibodies (mAbs), a similar requirement for human mAbs has been disputed. By using a mouse model humanized for its FcγRs and CD40, we revealed that FcγRIIB engagement is essential for the activity of human CD40 mAbs, while engagement of the activating FcγRIIA inhibits this activity. By engineering Fc variants with selective enhanced binding to FcγRIIB, but not to FcγRIIA, significantly improved antitumor immunity was observed. These findings highlight the necessity of optimizing the Fc domain for this class of therapeutic antibodies by using appropriate preclinical models that accurately reflect the unique affinities and cellular expression of human FcγR. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Differentiated Levels of Teacher Qualifications and the Structure of the Professional Teacher Standards

    Directory of Open Access Journals (Sweden)

    Zabrodin Yu.M.,

    2016-07-01

    Full Text Available This article discusses and analyzes the questions effect of professional standards for the preparation and development of professional resources, world experience in the development and implementation of professional standards, typical problems and necessary conditions for increasing the efficiency of the development and implementation of professional standards. The formation of labor functions of teaching staff requirements, taking into account the differentiated c skill levels are formulated in the study. Formulated requirements extend requirements for the qualification of workers which are determined with the Russian Ministry of Labor-specific professional activity types. The study proposed options for the construction of the structure of job functions of the professional teacher standard that correspond differentiated levels of staff qualifications.

  11. Development and Qualification of an Antenna Pointing Mechanism for the ExoMars High-Gain Antenna

    Science.gov (United States)

    St-Andre, Stephane; Dumais, Marie-Christine; Lebel, Louis-Philippe; Langevin, Jean-Paul; Horth, Richard; Winton, Alistair; Lebleu, Denis

    2015-09-01

    actuator’s auxiliary shaft through a tuned stiffness flex coupling.• Restriction for Electrical Power to Rotary Actuator: Each actuator is powered with less than 7 Watts. The maximum speed of the system is 0.5 deg/sec and it provides the required margin as per ECSS Requirements.The qualification tests, which have been performed successfully in 2014, have shown that the chosen solution is suitable for the ExoMars mission. The environment testing (vibration, shock, TVAC) and its life test over 120 days in TVAC were especially stringent. The new design passed the required 5.9 M output degrees of rotation without noticeable functionality degradation on components. The actuator drive axis stiffness shows a decrease after its life (≈-40 %), but the results were expected and within ExoMars requirements.The paper will present many lessons learned such as MGSE difficulties during the qualification test campaign, design choices to minimize the mechanism overall volume, packaging of different components and selection of the sine/cosine command profile to achieve a greater life on the mechanismAs of July 2015, the High Gain Antenna Assembly (HGA-A) has been integrated to the spacecraft for S/C level testing, and RF, Shock, Vibration, and EMC testing was successfully conducted.The ExoMars TGO High Gain Antenna Assembly Contract was carried out under a program of and funded by the European Space Agency.

  12. Audit Committee Quality and Financial Reporting Quality: A Study of Selected Indian Companies

    Directory of Open Access Journals (Sweden)

    Kanukuntla Shankaraiah

    2017-03-01

    Full Text Available This study examines audit committee quality and its relationship with financial reporting quality. The population of this study consists of the companies listed in Bombay Stock Exchange (BSE between years 2002 and 2012. Using Godden sample size formula, 133 companies are selected randomly for the study. It is found that in most of the equity based listed companies at BSE under study have complied with the legal formalities, for instance, appointment of independent directors, number of meetings, size of the audit committee, legal qualifications and financial qualifications of the directors, as they were required for the listing at a stock exchange in India. Further, the analysis and tests state that board size, audit committee meetings and its size have relationship with the financial reporting practices, but the CEO tenure and hold, board independence, net income, proportion of independent directors on board, legal qualifications and financial qualifications of the directors and overlap of audit committee members on compensation committee, have no influence on the financial reporting practices. Thus, it may be inferred that the companies may improve the financial reporting quality, by managing the board size, audit committee meetings and size, as these characteristics have significant relationship with financial reporting quality.

  13. 41 CFR 102-38.365 - Is a holding agency required to report property in “scrap” condition to its selected SC?

    Science.gov (United States)

    2010-07-01

    ... Sales Program § 102-38.365 Is a holding agency required to report property in “scrap” condition to its selected SC? No. Property which has no value except for its basic material content (scrap material) may be... agency should consult the SC(s) selected by the holding agency as to the feasibility of selling the scrap...

  14. QUALIFICATION FOR ADMISSION TO INTENSIVE PSYCHOTHERAPY IN A DAY HOSPITAL FOR NEUROTIC DISORDERS

    OpenAIRE

    Sobanski, Jerzy A.; Klasa, Katarzyna; Rutkowski, Krzysztof; Dembinska, Edyta; Müldner-Nieckowski, Łukasz

    2011-01-01

    Introduction: Qualification for treatment of neurotic disorders in a day hospital is connected with a process of selection carried out by experienced therapists – psychiatrists and psychologists – of patients for intensive, everyday group psychotherapy, combined withelements of individual therapy, as well as with the patients’ own decisions, made by them between ambulatory visits. Expectations and motivations of patients are the crucial indicators for the process of treatment. These factors i...

  15. Qualification of a computer program for drill string dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Stone, C.M.; Carne, T.G.; Caskey, B.C.

    1985-01-01

    A four point plan for the qualification of the GEODYN drill string dynamics computer program is described. The qualification plan investigates both modal response and transient response of a short drill string subjected to simulated cutting loads applied through a polycrystalline diamond compact (PDC) bit. The experimentally based qualification shows that the analytical techniques included in Phase 1 GEODYN correctly simulate the dynamic response of the bit-drill string system. 6 refs., 8 figs.

  16. Irradiation and beam tests qualification for ATLAS IBL Pixel Modules

    CERN Document Server

    Rubinskiy, Igor

    2013-01-01

    The upgrade for the ATLAS detector will have different steps towards HL-LHC. The first upgrade for the Pixel Detector will consist in the construction of a new pixel layer which will be installed during the first shutdown of the LHC machine (foreseen for 2013-14). The new detector, called Insertable B-Layer (IBL), will be inserted between the existing pixel detector and a new (smaller radius) beam-pipe at a radius of 33 mm. The IBL will require the development of several new technologies to cope with the increase of the radiation damage and the pixel occupancy and also to improve the physics performance, which will be achieved by reduction of the pixel size and of the material budget. Two different promising silicon sensor technologies (Planar n-in-n and 3D) are currently under investigation for the pixel detector. An overview of the sensor technologies’ qualification with particular emphasis on irradiation and beam tests are presented.

  17. Irradiation and beam tests qualification for ATLAS IBL Pixel Modules

    CERN Document Server

    Rubinskiy, I

    2013-01-01

    The upgrade for the ATLAS detector will have different steps towards HL-LHC. The first upgrade for the Pixel Detector will consist in the construction of a new pixel layer which will be installed during the first shutdown of the LHC machine (foreseen for 2013–2014). The new detector, called Insertable B-Layer (IBL), will be inserted between the existing Pixel Detector and a new (smaller radius) beam-pipe at a radius of 33 mm. The IBL will require the development of several new technologies to cope with the increase in the radiation damage and the pixel occupancy and also to improve the physics performance, which will be achieved by reduction of the pixel size and of the material budget. Two different promising silicon sensor technologies (Planar n-in-n and 3D) are currently under investigation for the Pixel Detector. An overview of the sensor technologies' qualification with particular emphasis on irradiation and beam tests is presented.

  18. SRNL PHASE 1 ASSESSMENT OF THE WAC/DQO AND UNIT OPERATIONS FOR THE WTP WASTE QUALIFICATION PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Peeler, D.; Adamson, D.; Bannochie, C.; Cozzi, A.; Eibling, R.; Hay, M.; Hansen, E.; Herman, D.; Martino, C.; Nash, C.; Pennebaker, F.; Poirier, M.; Reboul, S.; Stone, M.; Taylor-Pashow, K.; White, T.; Wilmarth, B.

    2012-05-16

    The Hanford Tank Waste Treatment and Immobilization Plant (WTP) is currently transitioning its emphasis from a design and construction phase toward start-up and commissioning. With this transition, the WTP Project has initiated more detailed assessments of the requirements related to actual processing of the Hanford Site tank waste. One particular area of interest is the waste qualification program to be implemented to support the WTP. Given the successful implementation of similar waste qualification efforts at the Savannah River Site (SRS), based on critical technical support and guidance from the Savannah River National Laboratory (SRNL), WTP requested the utilization of subject matter experts from SRNL to support a technology exchange to perform a review of the WTP waste qualification program, discuss the general qualification approach at SRS, and to identify critical lessons learned through the support of DWPF's sludge batch qualification efforts. As part of Phase 1, SRNL subject matter experts in critical technical and/or process areas reviewed specific WTP waste qualification information. The Phase 1 review was a collaborative, interactive, and iterative process between the two organizations. WTP provided specific analytical procedures, descriptions of equipment, and general documentation as baseline review material. SRNL subject matter experts reviewed the information and, as appropriate, requested follow-up information or clarification to specific areas of interest. This process resulted in multiple teleconferences with key technical contacts from both organizations resolving technical issues that lead to the results presented in this report. This report provides the results of SRNL's Phase 1 review of the WAC-DQO waste acceptance criteria and processability parameters, and the specific unit operations which are required to support WTP waste qualification efforts. The review resulted in SRNL providing concurrence, alternative methods, or gap

  19. Sensitive and selective culture medium for detection of environmental Clostridium difficile isolates without requirement for anaerobic culture conditions.

    Science.gov (United States)

    Cadnum, Jennifer L; Hurless, Kelly N; Deshpande, Abhishek; Nerandzic, Michelle M; Kundrapu, Sirisha; Donskey, Curtis J

    2014-09-01

    Effective and easy-to-use methods for detecting Clostridium difficile spore contamination would be useful for identifying environmental reservoirs and monitoring the effectiveness of room disinfection. Culture-based detection methods are sensitive for detecting C. difficile, but their utility is limited due to the requirement of anaerobic culture conditions and microbiological expertise. We developed a low-cost selective broth medium containing thioglycolic acid and l-cystine, termed C. difficile brucella broth with thioglycolic acid and l-cystine (CDBB-TC), for the detection of C. difficile from environmental specimens under aerobic culture conditions. The sensitivity and specificity of CDBB-TC (under aerobic culture conditions) were compared to those of CDBB (under anaerobic culture conditions) for the recovery of C. difficile from swabs collected from hospital room surfaces. CDBB-TC was significantly more sensitive than CDBB for recovering environmental C. difficile (36/41 [88%] versus 21/41 [51%], respectively; P = 0.006). C. difficile latex agglutination, an enzyme immunoassay for toxins A and B or glutamate dehydrogenase, and a PCR for toxin B genes were all effective as confirmatory tests. For 477 total environmental cultures, the specificity of CDBB-TC versus that of CDBB based upon false-positive yellow-color development of the medium without recovery of C. difficile was 100% (0 false-positive results) versus 96% (18 false-positive results), respectively. False-positive cultures for CDBB were attributable to the growth of anaerobic non-C. difficile organisms that did not grow in CDBB-TC. Our results suggest that CDBB-TC provides a sensitive and selective medium for the recovery of C. difficile organisms from environmental samples, without the need for anaerobic culture conditions. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

  20. Qualification of environmentally friendly cleaners

    Energy Technology Data Exchange (ETDEWEB)

    De Marquis, G.; Lopez, E.P.

    1995-05-01

    Sandia National Laboratories (SNL) has traditionally used chlorinated and fluorinated organic solvents for general degreasing applications. Many of these solvents have been labeled by the Federal Government as ozone depleting chemicals and as toxic and/or suspected carcinogens. As a result, these solvents will no longer be recommended for use within the DOE weapons complex. There are three major classes of materials that are of concern for cleaning: organics, metals and ceramics. Each of these materials has its own special cleaning problems. Solvents that were used in the past, such as 1,1,1-trichloroethane (TCA) and trichloroethylene (TCE), were extremely efficient at removing everything from oils and greases to salts without leaving corrosive residues or permanently absorbing into the materials. These traditional degreasing solvents were essentially ``all-inone`` cleaners: quick, reliable, and easy to use. Unfortunately, a ``drop-in`` cleaner for such a wide variety of materials and contaminants will probably never be identified. So far, it has been difficult to identify environmentally conscious cleaners that clean as well as TCE and TCA. Most alternative cleaners require more volume to do the job, and also require longer exposure to get the job done. With these things in mind, we are hoping to identify and qualify new cleaners that will take care of general classes of materials.

  1. 42 CFR 418.114 - Condition of participation: Personnel qualifications.

    Science.gov (United States)

    2010-10-01

    ...: Organizational Environment § 418.114 Condition of participation: Personnel qualifications. (a) General... Work Education; or a baccalaureate degree in psychology, sociology, or other field related to social...

  2. Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

    DEFF Research Database (Denmark)

    Schmidt, Johannes; Smith, Nicola J; Christiansen, Elisabeth

    2011-01-01

    given its size. Propionate, however, does not discriminate between FFA2 and the closely related receptor FFA3 (GPR41). To identify FFA2 selective ligands and understand the molecular basis for FFA2 selectivity, a targeted library of small carboxylic acids (SCAs) was examined using holistic, label...

  3. 24 CFR 941.602 - Applicability of other requirements.

    Science.gov (United States)

    2010-04-01

    ...) Procedure in the event of a conflict between requirements. In the event of a conflict between a requirement... using competitive proposal procedures for qualifications-based procurement (subject to negotiation of...

  4. Negative emotional appraisal selectively disrupts retrieval of expected outcome values required for goal-directed instrumental choice.

    Science.gov (United States)

    Pritchard, Tanya L; Weidemann, Gabrielle; Hogarth, Lee

    2017-09-14

    Stress induction reduces people's ability to modify their instrumental choices following changes in the value of outcomes, but the mechanisms underpinning this effect have not been specified because previous studies have lacked crucial control conditions. To address this, the current study had participants learn two instrumental responses for food and water, respectively, before water was devalued by specific satiety. Choice between these two responses was then measured in extinction, reacquisition and Pavlovian to instrumental transfer (PIT) tests. Concurrently during these tests, a negative emotional appraisal group evaluated aversive images (stress induction), whereas a control group evaluated neutral images, at the same time as choosing between the two instrumental responses. Negative emotional appraisal abolished the impact of water devaluation on instrumental choice in the extinction test, but did not affect instrumental choice in the reacquisition or PIT tests. These findings suggest that negative emotional appraisal selectively impaired participants' ability to retrieve the expected value of outcomes required to make goal-directed instrumental choices in the extinction test, and that this effect was not due to task disengagement, nullification of the devaluation treatment or impaired knowledge of response-outcome relationships.

  5. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

    Directory of Open Access Journals (Sweden)

    Li Xie

    Full Text Available Numerous genetic and epigenetic alterations render cancer cells selectively dependent on specific genes and regulatory pathways, and represent potential vulnerabilities that can be therapeutically exploited. Here we describe an RNA interference (RNAi-based synthetic interaction screen to identify genes preferentially required for proliferation of p53-deficient (p53- human cancer cells. We find that compared to p53-competent (p53+ human cancer cell lines, diverse p53- human cancer cell lines are preferentially sensitive to loss of the transcription factor ETV1 and the DNA damage kinase ATR. In p53- cells, RNAi-mediated knockdown of ETV1 or ATR results in decreased expression of the telomerase catalytic subunit TERT leading to growth arrest, which can be reversed by ectopic TERT expression. Chromatin immunoprecipitation analysis reveals that ETV1 binds to a region downstream of the TERT transcriptional start-site in p53- but not p53+ cells. We find that the role of ATR is to phosphorylate and thereby stabilize ETV1. Our collective results identify a regulatory pathway involving ETV1, ATR, and TERT that is preferentially important for proliferation of diverse p53- cancer cells.

  6. Infection-associated nuclear degeneration in the rice blast fungus Magnaporthe oryzae requires non-selective macro-autophagy.

    Directory of Open Access Journals (Sweden)

    Min He

    Full Text Available The rice blast fungus Magnaporthe oryzae elaborates a specialized infection structure called an appressorium to breach the rice leaf surface and gain access to plant tissue. Appressorium development is controlled by cell cycle progression, and a single round of nuclear division occurs prior to appressorium formation. Mitosis is always followed by programmed cell death of the spore from which the appressorium develops. Nuclear degeneration in the spore is known to be essential for plant infection, but the precise mechanism by which it occurs is not known.In yeast, nuclear breakdown requires a specific form of autophagy, known as piecemeal microautophagy of the nucleus (PMN, and we therefore investigated whether this process occurs in the rice blast fungus. Here, we report that M. oryzae possesses two conserved components of a putative PMN pathway, MoVac8 and MoTsc13, but that both are dispensable for nuclear breakdown during plant infection. MoVAC8 encodes a vacuolar membrane protein and MoTSC13 a peri-nuclear and peripheral ER protein.We show that MoVAC8 is necessary for caffeine resistance, but dispensable for pathogenicity of M. oryzae, while MoTSC13 is involved in cell wall stress responses and is an important virulence determinant. By functional analysis of ΔMoatg1 and ΔMoatg4 mutants, we demonstrate that infection-associated nuclear degeneration in M. oryzae instead occurs by non-selective macroautophagy, which is necessary for rice blast disease.

  7. Development of Reactive Barrier Polymers against Corrosion for the Oil and Gas Industry: From Formulation to Qualification through the Development of Predictive Multiphysics Modeling

    Directory of Open Access Journals (Sweden)

    Lefebvre X.

    2015-02-01

    Full Text Available Corrosion is a key issue for operators in the oil and gas industry since production fluids contain some water and both CO2 and H2S acid gases. In this context, this paper illustrates the development of a reactive barrier polymer against corrosion by H2S of offshore flexible pipes. The role of this reactive material, called anti-H2S material, is to avoid H2S reaching the structural steel layers of the flexible pipe during the whole service life of the structure, usually 20 years, and hence to place the steel layers in a sweet service environment. Placed between the existing pressure sheath and the steel layers, the anti-H2S material has the ability to neutralize H2S during its diffusion within the material. The neutralization is ensured by an irreversible chemical reaction on reactive components that are dispersed in the material. The raw material selection is based on both accurate requirements for their use in a flexible pipe and expected performances in a sour service environment over a long period of time. Some laboratory qualifications and experimental techniques are used to qualify the behavior of the material and build the material database. A dedicated multiphysics model is developed based on the coupling of permeation mechanisms and gas-solid reactions. Qualification of both the material and the model is performed thanks to middle-scale and full-scale tests conducted in representative sour service conditions.

  8. Development and validation of European guidelines for seismic qualification of post-installed anchors.

    Science.gov (United States)

    Mahrenholtz, Philipp; Wood, Richard L; Eligehausen, Rolf; Hutchinson, Tara C; Hoehler, Matthew S

    2017-10-01

    This paper presents the technical background for the seismic qualification procedures for post-installed anchors in the European Technical Approval Guideline (ETAG 001) seismic annex issued in 2013. We discuss requirements for a comprehensive guideline and reference supporting documentation. Numerical studies to generate new simulated seismic protocols for anchors are summarized with focus on their application to Europe. To reduce the time and cost of anchor product qualification testing while fulfilling the requirement of European building codes to assess two performance categories, we combine the results of our numerical studies to generate novel testing protocols that allow for the assessment of anchor behavior at multiple levels in a unified protocol. Validation tests demonstrate that the unified protocol results in anchor performance comparable with that achieved in multiple, single-performance-level tests.

  9. Preliminary Assessment of the Hanford Tank Waste Feed Acceptance and Product Qualification Programs

    Energy Technology Data Exchange (ETDEWEB)

    Herman, C. C.; Adamson, Duane J.; Herman, D. T.; Peeler, David K.; Poirier, Micheal R.; Reboul, S. H.; Stone, M. E.; Peterson, Reid A.; Chun, Jaehun; Fort, James A.; Vienna, John D.; Wells, Beric E.

    2013-04-01

    The U.S. Department of Energy Office of Environmental Management (EM) is engaging the national laboratories to provide the scientific and technological rigor to support EM program and project planning, technology development and deployment, project execution, and assessment of program outcomes. As an early demonstration of this new responsibility, Savannah River National Laboratory (SRNL) and Pacific Northwest National Laboratory (PNNL) have been chartered to implement a science and technology program addressing Hanford Tank waste feed acceptance and product qualification. As a first step, the laboratories examined the technical risks and uncertainties associated with the planned waste feed acceptance and qualification testing for Hanford tank wastes. Science and technology gaps were identified for work associated with 1) feed criteria development with emphasis on identifying the feed properties and the process requirements, 2) the Tank Waste Treatment and Immobilization Plant (WTP) process qualification program, and 3) the WTP HLW glass product qualification program. Opportunities for streamlining the accetpance and qualification programs were also considered in the gap assessment. Technical approaches to address the science and technology gaps and/or implement the opportunities were identified. These approaches will be further refined and developed as strong integrated teams of researchers from national laboratories, contractors, industry, and academia are brought together to provide the best science and technology solutions. Pursuing the identified approaches will have immediate and long-term benefits to DOE in reducing risks and uncertainties associated with tank waste removal and preparation, transfers from the tank farm to the WTP, processing within the WTP Pretreatment Facility, and in producing qualified HLW glass products. Additionally, implementation of the identified opportunities provides the potential for long-term cost savings given the anticipated

  10. Lightning arrestor connector lead magnesium niobate qualification pellet test procedures.

    Energy Technology Data Exchange (ETDEWEB)

    Tuohig, W. (Honeywell FM& T, Kansas City, MO); Mahoney, Patrick A.; Tuttle, Bruce Andrew; Wheeler, Jill Susanne

    2009-02-01

    Enhanced knowledge preservation for DOE DP technical component activities has recently received much attention. As part of this recent knowledge preservation effort, improved documentation of the sample preparation and electrical testing procedures for lead magnesium niobate--lead titanate (PMN/PT) qualification pellets was completed. The qualification pellets are fabricated from the same parent powders used to produce PMN/PT lightning arrestor connector (LAC) granules at HWF&T. In our report, the procedures for fired pellet surface preparation, electrode deposition, electrical testing and data recording are described. The dielectric measurements described in our report are an information only test. Technical reasons for selecting the electrode material, electrode size and geometry are presented. The electrical testing is based on measuring the dielectric constant and dissipation factor of the pellet during cooling from 280 C to 220 C. The most important data are the temperature for which the peak dielectric constant occurs (Curie Point temperature) and the peak dielectric constant magnitude. We determined that the peak dielectric constant for our procedure would be that measured at 1 kHz at the Curie Point. Both the peak dielectric constant and the Curie point parameters provide semi-quantitative information concerning the chemical and microstructural homogeneity of the parent material used for the production of PMN/PT granules for LACs. Finally, we have proposed flag limits for the dielectric data for the pellets. Specifically, if the temperature of the peak dielectric constant falls outside the range of 250 C {+-} 30 C we propose that a flag limit be imposed that will initiate communication between production agency and design agency personnel. If the peak dielectric constant measured falls outside the range 25,000 {+-} 10,000 we also propose that a flag limit be imposed.

  11. B-Plant D-Filter detector system qualification test report

    Energy Technology Data Exchange (ETDEWEB)

    Ritter, G.A., Westinghouse Hanford

    1996-08-23

    This report summarizes the results of qualification testing of the B Plant D-Filter Detector System. The purpose of this test was to verify that the system meets the performance requirements and that the unit is ready for field deployment. Testing was performed in the test pit in the 306E Facility. This detector system will be deployed in the B Plant D-Filter to measure beta/gamma dose rates from the filter bank.

  12. SRS SLUDGE BATCH QUALIFICATION AND PROCESSING; HISTORICAL PERSPECTIVE AND LESSONS LEARNED

    Energy Technology Data Exchange (ETDEWEB)

    Cercy, M.; Peeler, D.; Stone, M.

    2013-09-25

    This report provides a historical overview and lessons learned associated with the SRS sludge batch (SB) qualification and processing programs. The report covers the framework of the requirements for waste form acceptance, the DWPF Glass Product Control Program (GPCP), waste feed acceptance, examples of how the program complies with the specifications, an overview of the Startup Program, and a summary of continuous improvements and lessons learned. The report includes a bibliography of previous reports and briefings on the topic.

  13. [Medico-expert qualification of iatrogenic diseases].

    Science.gov (United States)

    Belikov, E S

    1998-01-01

    Medical expert qualification of iatrogenic disease is developed on the basis of insurance assessment of events (accident, realized risk, error) and classification of their causes according to the principle of the triad patient-medical professional-environment taking into account medical technology (diagnosis, treatment, rehabilitation, prophylaxis). Medical error is considered as an integral term and include inadequate (erroneous) professional thinking and/or action. Therefore, it is suggested to qualify a medical error either as a fallacy, or negligence, or omission. Medical-technological standards, apart from legitimacy, are necessary for realization of an expert activity.

  14. Qualification test and analysis report: solar collectors

    Energy Technology Data Exchange (ETDEWEB)

    1978-12-01

    Test results show that the Owens-Illinois Sunpak/sup TM/ Model SEC 601 air-cooled collector meets the national standards and codes as defined in the Subsystem Performance Specification and Verification Plan of NASA/MSFC Contract NAS8-32259, dated October 28, 1976. The architectural and engineering firm of Smith, Hinchman and Grylls, Detroit, Michigan, acted in the capacity of the independent certification agency. The program calls for the development, fabrication, qualification and delivery of an air-liquid solar collector for solar heating, combined heating and cooling, and/or hot water systems.

  15. Anticorrosive field joint coating qualification, heat shrinkable sleeve; Qualificacao de revestimento anticorrosivo para juntas de campo, mantas termocontrateis

    Energy Technology Data Exchange (ETDEWEB)

    Cabral, Glaucia B.; Koebsch, Andre; Castinheiras Junior, Wilson [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2005-07-01

    The main objective of this job is to present the quality requirements fixed by PETROBRAS for anticorrosive field joint coating for buried pipelines, industrially coated with PE-3L. It describes the used system - polyethylene based heat shrinkable sleeve - comparing with the existent on the pipeline. So, it exposes the suppliers' qualification stages, which include test carried out for the materials, for the sleeve set and for the coating after its application on the joint field. Finally, it shows that the experience, which has been gotten in the qualification, consolidated the quality control systematic that have been carry out during the sleeves acquisition and application at the pipeline construction. (author)

  16. A study on the implementation of an integrated Environmental Qualification Management System(EQMS) for nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Bhang, Keug Jin; Jeong, Sun Chul; Kang, Pil Sun [KHNP CRI, Daejeon (Korea, Republic of)

    2012-10-15

    Environmental Qualification Management System(EQMS) for Nuclear Power Plant is a web based program for preventing degradation and managing original functions of environmental qualification equipment during nuclear power plant life cycle by inspecting and improving status of them periodically. But cognitive issues have stayed in the construction phase of EQMS: almost EQ equipment are not registered in DREAMS because the approach is not based on a standard data structure. In this study, we are to obtain the requirements of integrated EQMS by considering a standard and surveying the problems of current EQMS.

  17. Qualification and Issues with Space Flight Laser Systems and Components

    Science.gov (United States)

    Ott, Melanie N.; Coyle, D. Barry; Canham, John S.; Leidecker, Henning W.

    2006-01-01

    The art of flight quality solid-state laser development is still relatively young, and much is still unknown regarding the best procedures, components, and packaging required for achieving the maximum possible lifetime and reliability when deployed in the harsh space environment. One of the most important issues is the limited and unstable supply of quality, high power diode arrays with significant technological heritage and market lifetime. Since Spectra Diode Labs Inc. ended their involvement in the pulsed array business in the late 199O's, there has been a flurry of activity from other manufacturers, but little effort focused on flight quality production. This forces NASA, inevitably, to examine the use of commercial parts to enable space flight laser designs. System-level issues such as power cycling, operational derating, duty cycle, and contamination risks to other laser components are some of the more significant unknown, if unquantifiable, parameters that directly effect transmitter reliability. Designs and processes can be formulated for the system and the components (including thorough modeling) to mitigate risk based on the known failures modes as well as lessons learned that GSFC has collected over the past ten years of space flight operation of lasers. In addition, knowledge of the potential failure modes related to the system and the components themselves can allow the qualification testing to be done in an efficient yet, effective manner. Careful test plan development coupled with physics of failure knowledge will enable cost effect qualification of commercial technology. Presented here will be lessons learned from space flight experience, brief synopsis of known potential failure modes, mitigation techniques, and options for testing from the system level to the component level.

  18. Expanding the frontiers of national qualifications frameworks through lifelong learning

    Science.gov (United States)

    Owusu-Agyeman, Yaw

    2017-10-01

    The adoption of a national qualifications framework (NQF) by some governments in all world regions has shown some success in the area of formal learning. However, while NQFs continue to enhance formal learning in many countries, the same cannot be said for the recognition, validation and accreditation (RVA) of non-formal and informal learning. Focusing on competency-based technical and vocational education and training (TVET) within its NQF, Ghana introduced the National Technical and Vocational Education and Training Qualifications Framework (NTVETQF) as a sub-framework in 2012. In the wake of the NTVETQF's limited success, the author of this article reasons that a lifelong learning approach could enhance its effectiveness considerably. Comparing national and international policies, he argues that the NTVETQF should be able to properly address the issues of progression from informal and non-formal to formal modes of lifelong learning within the country's broad context of education. In addition, the study conceptualises the integration of lifelong learning within a broad NQF in four key domains: (1) individual; (2) institutional; (3) industry; and (4) state. The author concludes that, for the NTVETQF to achieve its goal of facilitating access to further education and training while also promoting lifelong learning for all (including workers in the informal economy), effective integration of all modes of lifelong learning is required. Although this entails some challenges, such as recognition of prior learning and validation of all modes of learning, it will help to widen access to education as well as providing individuals with a pathway for achieving their educational aspirations.

  19. The qualifications business in higher education | Berkhout | South ...

    African Journals Online (AJOL)

    performance of a person, the closer we are to attaining a valuable human resource or reliably saleable qualification. This article explores some of the implications of this for developments in higher education in the context of the growing internationalisation and commercialisation of the assessment and qualification business ...

  20. Qualification and Lessons Learned with Space Flight Fiber Optic Components

    Science.gov (United States)

    Ott, Melanie

    2007-01-01

    This presentation covers lessons learned during the design, development, manufacturing and qualification of space flight fiber optic components. Changes at NASA, including short-term projects and decreased budgets have brought about changes to vendors and parts. Most photonics for NASA needs are now commercial off the shelf (COTS) products. The COTS Tecnology Assurance approach for space flight and qualification plans are outlined.

  1. Job Outcomes among Korean Graduates with Vocational Qualifications

    Science.gov (United States)

    Lee, Young-Min; Cho, Sung-Eun

    2017-01-01

    Purpose: The purpose of this paper is to ascertain the status of recent Korean four-year college students' acquisition of vocational qualification certificates (hereinafter "certificates" or "qualifications"), the factors that influence certificate acquisition, and the resulting employment and wage effects.…

  2. Qualification Users' Perceptions and Experiences of Assessment Reliability

    Science.gov (United States)

    Chamberlain, Suzanne

    2013-01-01

    This paper presents the findings of a study designed to explore qualification users' perceptions and experiences of reliability in the context of national assessment outcomes in England. The study consisted of 17 focus groups conducted across six sectors of qualification users: students, teachers, trainee teachers, job-seekers, employers and…

  3. 30 CFR 75.155 - Qualified hoisting engineer; qualifications.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Qualified hoisting engineer; qualifications. 75... Persons § 75.155 Qualified hoisting engineer; qualifications. (a)(1) A person is a qualified hoisting engineer within the provisions of subpart O of this part, for the purpose of operating a steam-driven hoist...

  4. 32 CFR 935.121 - Qualifications of peace officers.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Qualifications of peace officers. 935.121... AND INSULAR REGULATIONS WAKE ISLAND CODE Peace Officers § 935.121 Qualifications of peace officers. Any person appointed as a peace officer must be a citizen of the United States and have attained the...

  5. Qualifications Frameworks: Expanding Influence, Persisting Obstacles. Briefing Note

    Science.gov (United States)

    Cedefop - European Centre for the Development of Vocational Training, 2014

    2014-01-01

    Initial work on the European qualifications framework (EQF) started in autumn 2004. Partly triggered by this initiative, qualifications frameworks have since become integral parts of almost all education and training systems in Europe. Outside Europe, more and more countries and regions (such as Asia-Pacific) are rapidly developing and…

  6. Qualification Plus: Performance and Durability Tests Beyond IEC 61215 (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, S.; Jordan, J.; Kempe, M.; Miller, D.; Bosco, N.; Silverman, T.; Hacke, P.; Phillips, N.; Earnest, T.; Romero, R.

    2014-03-01

    Qualification Plus is an accelerated test protocol and quality management system that gives higher confidence in field performance of PV modules compared with conventional qualification testing. The test sequences are being developed as consensus standards, but the early publication of these tests enables the community to begin benefiting from them sooner.

  7. 16 CFR 703.4 - Qualification of members.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Qualification of members. 703.4 Section 703... Mechanism § 703.4 Qualification of members. (a) No member deciding a dispute shall be: (1) A party to the... of its acquisition or ownership solely for investment. (b) When one or two members are deciding a...

  8. Qualifications frameworks in Africa: A critical reflection | Higgs ...

    African Journals Online (AJOL)

    As more and more countries and regions across the world develop qualifications frameworks to improve harmonisation of education and training systems and comparability of qualifications, it is becoming increasingly evident that Africa has not remained unaffected. At present more than twenty African countries are actively ...

  9. Regional Foods and Rural Development: The Role of Product Qualification

    Science.gov (United States)

    Tregear, Angela; Arfini, Filippo; Belletti, Giovanni; Marescotti, Andrea

    2007-01-01

    Qualification schemes have become popular tools for supporting regional foods, yet little is understood about the impacts they have on the rural development contribution of such foods. Qualification processes may stimulate new networks and community actions, but they may also be incompatible with strategies of extended territorial development…

  10. 32 CFR 935.139 - Motor vehicle operator qualifications.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Motor vehicle operator qualifications. 935.139... AND INSULAR REGULATIONS WAKE ISLAND CODE Motor Vehicle Code § 935.139 Motor vehicle operator qualifications. (a) No person may operate a privately owned motor vehicle on Wake Island unless he has an island...

  11. 10 CFR 603.515 - Qualification of a consortium.

    Science.gov (United States)

    2010-01-01

    ... Business Evaluation Recipient Qualification § 603.515 Qualification of a consortium. (a) A consortium that... articles of collaboration, which sets out the rights and responsibilities of each consortium member. This... consortium's (1) Management structure; (2) Method of making payments to consortium members; (3) Means of...

  12. Qualifications Frameworks and Their Conflicting Social Imaginaries of Globalisation

    Science.gov (United States)

    Louise Sarauw, Laura

    2012-01-01

    Critics often see the European Bologna Process as a univocal standardisation of higher education. By exploring how different qualifications frameworks project different social imaginaries of globalisation, this article takes a different stance. The overarching qualifications framework of the Bologna Process rests on a socially constituted and…

  13. The European Qualification Framework: Skills, Competences or Knowledge?

    Science.gov (United States)

    Mehaut, Philippe; Winch, Christopher

    2012-01-01

    The European Qualification Framework (EQF) is intended to transform European national qualification frameworks (NQFs) by moulding them into a learning outcomes framework. Currently adopted as an enabling law by the European Union, the EQF has now operated for several years. In order to secure widespread adoption, however, it will be necessary for…

  14. Here, KAPTUR This! Identifying and Selecting the Infrastructure Required to Support the Curation and Preservation of Visual Arts Research Data

    Directory of Open Access Journals (Sweden)

    Leigh Garrett

    2013-11-01

    Full Text Available Research data is increasingly perceived as a valuable resource and, with appropriate curation and preservation, it has much to offer learning, teaching, research, knowledge transfer and consultancy activities in the visual arts. However, very little is known about the curation and preservation of this data: none of the specialist arts institutions have research data management policies or infrastructure and anecdotal evidence suggests that practice is ad hoc, left to individual researchers and teams with little support or guidance. In addition, the curation and preservation of such diverse and complex digital resources as found in the visual arts is, in itself, challenging. Led by the Visual Arts Data Service, a research centre of the University for the Creative Arts, in collaboration with the Glasgow School of Art; Goldsmiths College, University of London; and University of the Arts London, and funded by JISC, the KAPTUR project (2011-2013 seeks to address the lack of awareness and explore the potential of research data management systems in the arts by discovering the nature of research data in the visual arts, investigating the current state of research data management, developing a model of best practice applicable to both specialist arts institutions and arts departments in multidisciplinary institutions, and by applying, testing and piloting the model with the four institutional partners. Utilising the findings of the KAPTUR user requirement and technical review, this paper will outline the method and selection of an appropriate research data management system for the visual arts and the issues the team encountered along the way.

  15. Professional Qualifications of Teachers for English for Primary and Secondary Education--A Brief Comparison between Hong Kong and China

    Science.gov (United States)

    Mak, Barley

    2016-01-01

    Entry to the teaching career in most education systems nowadays is based on academic qualifications and professional credentials. The requirements and trainings for teachers of English vary in different regions and countries. This short review presents the professional preparation of pre-service teachers of English and the English language…

  16. Developing competence based qualification system in the nuclear energy sector

    Energy Technology Data Exchange (ETDEWEB)

    Ceclan, Mihail [European Commission, Petten (Netherlands). Inst. for Energy and Transport

    2016-04-15

    The Institute for Energy and Transport of the Joint Research Centre, European Commission, developed a strategy and road map for ECVET implementation. The JRC road map for European Credit System for Vocational Education and Training (ECVET) implementation has reached the stage of Competence-Based Qualification System development. The Competence-Based Qualification System can help bridge the gap between Human Resources demand and supply in the nuclear market by structuring qualifications in small independent parts. This very specific ECVET feature of a qualification, facilitates the process of competences accumulation and the lifelong learning, mobility and flexible learning pathways. New developments are presented about the Competence-Based Qualification System development for the nuclear energy sector.

  17. Team Formation under Normal versus Crisis Situations: Leaders' Assessments of Task Requirements and Selection of Team Members

    National Research Council Canada - National Science Library

    Baltos, Georgios; Mitsopoulou, Zoi

    2007-01-01

    ... with, and reliability of candidate team members. Motivation, professional capabilities, and leadership skills are the most preferred selection variables when the organizational situation is perceived as a crisis.

  18. Guide for Oxygen Component Qualification Tests

    Science.gov (United States)

    Bamford, Larry J.; Rucker, Michelle A.; Dobbin, Douglas

    1996-01-01

    Although oxygen is a chemically stable element, it is not shock sensitive, will not decompose, and is not flammable. Oxygen use therefore carries a risk that should never be overlooked, because oxygen is a strong oxidizer that vigorously supports combustion. Safety is of primary concern in oxygen service. To promote safety in oxygen systems, the flammability of materials used in them should be analyzed. At the NASA White Sands Test Facility (WSTF), we have performed configurational tests of components specifically engineered for oxygen service. These tests follow a detailed WSTF oxygen hazards analysis. The stated objective of the tests was to provide performance test data for customer use as part of a qualification plan for a particular component in a particular configuration, and under worst-case conditions. In this document - the 'Guide for Oxygen Component Qualification Tests' - we outline recommended test systems, and cleaning, handling, and test procedures that address worst-case conditions. It should be noted that test results apply specifically to: manual valves, remotely operated valves, check valves, relief valves, filters, regulators, flexible hoses, and intensifiers. Component systems are not covered.

  19. Qualification according to PDI's techniques UT EPRI methodology Phased Array for the inspection of vessels of PWR reactor with advanced robotic equipment; Cualificacion segun metodologia PDI de EPRI de te cnicas UT Phased Array para la inspeccion de vasijas de reactor PWR con eq uipos roboticos avanzados

    Energy Technology Data Exchange (ETDEWEB)

    Gadea, J. R.; Gonzalez, P.; Fernandez, F.

    2014-07-01

    The techniques and procedures qualified in the program EPRI PDI are directly applicable in plants whose reference code is ASME XI - specifically the Appendix VIII-, mainly USA and countries in which it is established American PWR technology. While countries with reactors in operation technology ABB (Sweden) or type VVER (Finland and Eastern countries) requires a qualification of specific technical type ENIQ, PDI qualification is a valuable reference since it allows to deal with such qualifications with guarantees. (Author)

  20. Qualification of tritium permeation barriers in liquid Pb-17Li

    Energy Technology Data Exchange (ETDEWEB)

    Aiello, A. E-mail: antonio.aiello@brasimone.enea.it; Ricapito, I.; Benamati, G.; Ciampichetti, A

    2003-09-01

    The reduction of tritium permeation from the Pb-17Li, or plasma, into the coolant is of crucial importance in order to reduce the radiological hazard in the steam generator vault as well as in the turbine/condenser area and to optimise the tritium balance in the reactor. The use of aluminium rich coatings has been selected as reference solution for the water cooled lithium lead (WCLL) blanket in order to produce reliable tritium permeation barriers (TPB). TPB qualification activities performed in the past allowed the selection of two reference deposition techniques, the chemical vapour deposition (CVD) process developed on laboratory scale by CEA, and the hot dipping (HD) process developed by FZK. On the basis of the results obtained in the past with the Corelli I-II devices, a new apparatus named Vivaldi was designed to perform comparative tests on two hollow cylindrical specimens in the same operating conditions. The performance of alumina coating on EUROFER 97 steel has been tested in gas and liquid metal phase. The obtained results in terms of permeated fluxes and permeation reduction factors (PRF) are herein presented and discussed. A post experiment examination of coatings was performed by use of optical and SEM microscopy.

  1. Calibration and qualification of equipment in the pharmaceutical industry: emphasis on radiopharmaceuticals production

    Energy Technology Data Exchange (ETDEWEB)

    Melero, Laura T.U.H.; Silva, Katia S. da S.; Zanette, Camila; Araujo, Elaine B. de; Mengatti, Jair [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2011-07-01

    The calibration and qualification of equipment are listed items in RDC number 17 of 2010 which refers about the Good Manufacturing Practice (GMP) of medicaments and RDC number 63 of 2009 which refers about GMP of Radiopharmaceuticals. Both are essential requirements since they are involved in process control to attend the regulatory criteria and are a key part of the validation process. The aim of this work is presenting the importance of calibration and qualification, and the routine use of equipment and facilities in industrial scale production of radiopharmaceuticals in the IPEN/CNEN. The radiopharmacy of IPEN is a pharmaceutical industry that produces radiopharmaceuticals for diagnosis and therapy. It was the pioneer institute in production of radioisotopes and radiopharmaceuticals in Brazil. Currently, 38 products are distributed to the nuclear medicine centers, including primary radioisotopes, labeled molecules and lyophilized reagents for labeling with technetium-99m. To fulfill the GMP requirements for quality assurance of products, several factors must be considered including infrastructure, equipment and raw materials beyond, obviously, the whole production process should be controlled until the release of the final product. Therefore, the calibration and verification of equipment, instruments and other appliances used in the production and quality control should be performed. A program of calibration, qualification and requalification of equipment used in production and quality control of radiopharmaceuticals is necessary for the validation of production processes and analytical methods, and should be established for quality assurance of produced radiopharmaceuticals. (author)

  2. Qualifications and Competencies for Population Health Management Positions: A Content Analysis of Job Postings.

    Science.gov (United States)

    Meyer, Melanie

    2017-12-01

    The need for population health management expertise has increased as the health care industry shifts toward value-based care. However, many organizations report hiring gaps as they seek to fill positions. The purpose of this study was to analyze the types of population health management positions for which health care organizations are hiring, including qualifications and competencies required for these positions. A content analysis was conducted on 271 job postings collected during a 2-month period. A typology of qualifications and competencies was developed based on the content analysis. Profiles were generated for the top 5 job title classifications: directors, coordinators, care managers, analysts, and specialists. This study highlights the investment health care organizations are making in population health management and the prominent role these positions are playing in the health care environment today. Many organizations are building out population health management teams resulting in multiple positions at different levels being added. As the market demands competent candidates who are equipped with specialized population health expertise as well as practical experience in program development, technology applications, care management, and analytics, professional education programs will need to adapt curricula to address the required areas. Competencies for specific job title classifications may need further evaluation and refinement over time. Study results can be used by organizations for strategic planning, by educators to target needed qualifications and competencies, and by researchers and policy advisors to assess progress toward value-based care.

  3. Use and qualification of primary and secondary standards employed in quantitative ¹H NMR spectroscopy of pharmaceuticals.

    Science.gov (United States)

    Rundlöf, Torgny; McEwen, Ian; Johansson, Monika; Arvidsson, Torbjörn

    2014-05-01

    Standards are required in quantitative NMR (qNMR) to obtain accurate and precise results. In this study acetanilide was established and used as a primary standard. Six other chemicals were selected as secondary standards: 3,4,5-trichloropyridine, dimethylterephthalate, maleic acid, 3-sulfolene, 1,4-bis(trimethylsilyl)benzene, and 1,3,5-trimethoxybenzene. The secondary standards were quantified using the primary standard acetanilide. A protocol for qualification and periodic checks of these secondary standards was developed, and used for evaluation of the stability of the compounds. Periodic monitoring of purity was performed for several years. The purity was higher than 99% for all secondary standards. All standards maintained the initial purity during the time period of monitoring, with very small variations in purity (0.3-0.4%). The selected secondary standards were shown to be suitable qNMR standards and that periodic requalification of the standards by qNMR ensures reliable analytical results. These standards have been used in our laboratory for compliance testing of pharmaceutical active substances and approved medicinal products as well as for analysis of suspected illegal medicines. In total more than 1000 samples have been tested using both internal and external standardization and examples are given. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Comparison of selected DOE and non-DOE requirements, standards, and practices for Low-Level Radioactive Waste Disposal

    Energy Technology Data Exchange (ETDEWEB)

    Cole, L. [Cole and Associates (United States); Kudera, D.; Newberry, W. [Lockheed Idaho Technologies Co., Idaho Falls, ID (United States)

    1995-12-01

    This document results from the Secretary of Energy`s response to Defense Nuclear Facilities Safety Board Recommendation 94--2. The Secretary stated that the US Department of Energy (DOE) would ``address such issues as...the need for additional requirements, standards, and guidance on low-level radioactive waste management. `` The authors gathered information and compared DOE requirements and standards for the safety aspects Of low-level disposal with similar requirements and standards of non-DOE entities.

  5. Revision of the qualification framework at the Technical University of Denmark Part 2

    DEFF Research Database (Denmark)

    Henneberg, Kaj-Åge; Kuhn, Luise Theil; Jungersen, Gregers

    2017-01-01

    Using a revised Qualification Framework (QF) with four main categories: -to know, - to be, -to interact, and -to do, this paper demonstrates how to use the elements of the QF to construct Programme-Qualification Matrices. A general Programme- Qualification Matrix defines the qualifications and th...

  6. Intracellular amastigote replication may not be required for successful in vitro selection of miltefosine resistance in Leishmania infantum.

    Science.gov (United States)

    Hendrickx, S; Mondelaers, A; Eberhardt, E; Lachaud, L; Delputte, P; Cos, P; Maes, L

    2015-07-01

    Although miltefosine (MIL) has only recently been positioned as a first-line therapeutic option for visceral leishmaniasis, field reports note an increasing trend in treatment failures. Study of laboratory selected MIL-resistant strains is needed in the absence of confirmed resistant clinical isolates. In contrast to promastigotes, experimental in vitro selection of MIL-resistance on intracellular amastigotes has not yet been documented. This study reports for the first time the selection of MIL-resistance in Leishmania infantum LEM3323, a strain which clearly shows active intracellular replication. Starting from the hypothesis that active multiplication may be essential in the resistance selection process; several other L. infantum strains were evaluated. Although strain LEM5269 showed only marginally lower intracellular multiplication, selection for resistance failed, as was also the case for several other strains showing poor or no intracellular replication. These results suggest that intracellular multiplication may not be an absolute prerequisite for the outcome of experimental in vitro MIL-resistance selection in clinical field isolates.

  7. The COPD Biomarker Qualification Consortium (CBQC)

    DEFF Research Database (Denmark)

    Casaburi, Richard; Celli, Bartolome; Crapo, James

    2013-01-01

    Abstract Knowledge about the pathogenesis and pathophysiology of chronic obstructive pulmonary disease (COPD) has advanced dramatically over the last 30 years. Unfortunately, this has had little impact in terms of new treatments. Over the same time frame, only one new class of medication for COPD......, and no interested party has been in a position to undertake such a process. In order to facilitate the development of novel tools to assess new treatments, the Food and Drug Administration, in collaboration with the COPD Foundation, the National Heart Lung and Blood Institute and scientists from the pharmaceutical...... industry and academia conducted a workshop to survey the available information that could contribute to new tools. Based on this, a collaborative project, the COPD Biomarkers Qualification Consortium, was initiated. The Consortium in now actively preparing integrated data sets from existing resources...

  8. Sodium-glucose cotransporter 2 inhibitor use: A pharmaco-ergonomic qualification tool

    Directory of Open Access Journals (Sweden)

    Sanjay Kalra

    2017-01-01

    Full Text Available Pharmaco-ergonomics implies tailoring the drug therapy to an individual patient's requirement(s. The development of sodium-glucose cotransporter 2 inhibitor (SGLT2-i agents has impelled multiple clinical considerations, in the management of type-2 diabetes. This paper attempts to summarize the pharmaco-ergonomic considerations for these agents, in the form of an SGLT2-i qualification tool, based on a clinical score. This tool may serve as a simple and inexpensive practical guide, to optimize the risk-benefit considerations for SGLT2-i agents.

  9. Co-operation Equipment Qualification for Safety grade I and C Equipment between Russia and Korea

    Energy Technology Data Exchange (ETDEWEB)

    Ham, J. K.; Lee, D. H.; Park, J. W.; Jeong, M. H.; Choi, Y. H.; Suh, J. J.; Jang, T. H. [Korea Testing Laboratory, Seoul (Korea, Republic of)

    2007-06-15

    Equipment Qualification technology for I and C system on nuclear grade have been approved with accurate and safe for verifying and validation. It contributes to acknowledge of reliability and to review of user approval. Also it did not completely satisfied the requirement of Russia, it can be satisfied by bit of modification on design. It is expected to support the export of safety PLC to nuclear power plant. Proven EQ technology is required on the further markets of nuclear. Therefore, comparison test with foreign country is necessary to support the mutual accreditation of EQ for export of domestic products.

  10. Unmanned Aerial Vehicle/Remotely Piloted Aircraft Design Selection Based on Service-Stated Meteorological/Oceanographic Requirements

    National Research Council Canada - National Science Library

    Stanton, Robert

    1999-01-01

    ... (written in Structured Query Language) links RPA flight performance parameters to individualized METOC Elements of Measurement, a subset of a larger Joint Service METOC Requirements database table, presented elsewhere in the thesis in full...

  11. 34 CFR 86.102 - What is required of an IHE that the Secretary selects for annual review?

    Science.gov (United States)

    2010-07-01

    ... DRUG AND ALCOHOL ABUSE PREVENTION Institutions of Higher Education § 86.102 What is required of an IHE... program. (Approved by the Office of Management and Budget under control number 1880-0522) (Authority: 20 U...

  12. Seismic qualification tests of fans of the NPP of Laguna Verde U-1 and U-2; Pruebas de calificacion sismica de ventiladores de la Central Laguna Verde U1 and U2

    Energy Technology Data Exchange (ETDEWEB)

    Jarvio C, G.; Garcia H, E. E.; Arguelles F, R.; Vela H, A. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Naranjo U, J. L., E-mail: gilberto.jarvio@inin.gob.mx [Comision Federal de Electricidad, Gerencia de Centrales Nucleoelectricas, Subgerencia de Ingenieria, Carretera Veracruz-Medellin Km 7.5, Dos Bocas, Veracruz (Mexico)

    2013-10-15

    This work presents the results of the seismic qualification tests applied to the fans that will be installed in the control panels of the three divisions of the diesel generators of the nuclear power plant (NPP) of Laguna Verde, Unit-1 and Unit-2. This seismic qualification process of the fans was carried out using two specimens that were tested in the seismic table (vibrating) of the Engineering Institute of Universidad Nacional Autonoma de Mexico (UNAM), in accordance with the requirements of the standard IEEE 344-1975, to satisfy the established requirements of seismic qualification in the technical specifications and normative documents required by the nuclear standards, in order to demonstrate its application in the diesel generators Divisions I, II and III of the NPP. The seismic qualification tests were developed on specimens that were retired of the NPP of Laguna Verde recently with a service life of 7.75 years. (Author)

  13. 5P/4P/3P/2P Battery Modules Range Generic Development & Qualification

    Science.gov (United States)

    Remy, S.; Tricot, H.; Du Peyrat, D.

    2011-10-01

    As an answer to a larger energy range need for Geostationary battery, at the same time of shorter lead time combined with low recurring activities budgets, Saft set-up a range of generic battery modules from 2P VES180SA Li-ion cells to 5P VES180SA Li-ion cells. This battery range is based on a generic and modular battery approach, including innovating concepts such as parallel multi layers bus bars. The full qualification of the battery range has been successfully achieved at the end of 2010 year. The aim of this paper is to present the main principles of the battery design, to highlight the modular concepts of the battery parts so as to minimize technical differences between each size of module. It will also reflect the interfaces commonalties on the mechanical and electrical point of view, to provide interchangeable battery blocks even at a later stage of the project. The paper will also present the overall qualification plan and key results based on an envelope approach to cover generic geostationary requirements for different platforms. A specific paragraph will emphasize the design and proven performances of the largest module of the current range (5P10S VES180SA battery). A last chapter will present the already contracted projects based on this battery range design & qualification status.

  14. Transportability of tertiary qualifications and CPD: a continuing challenge for the global health workforce.

    Science.gov (United States)

    Saltman, Deborah C; Kidd, Michael R; Jackson, Debra; Cleary, Michelle

    2012-07-09

    In workforces that are traditionally mobile and have long lead times for new supply, such as health, effective global indicators of tertiary education are increasingly essential. Difficulties with transportability of qualifications and cross-accreditation are now recognised as key barriers to meeting the rapidly shifting international demands for health care providers. The plethora of mixed education and service arrangements poses challenges for employers and regulators, let alone patients; in determining equivalence of training and competency between individuals, institutions and geographical locations. This paper outlines the shortfall of the current indicators in assisting the process of global certification and competency recognition in the health care workforce. Using Organisation for Economic Cooperation and Development (OECD) data we highlight how International standardisation in the tertiary education sector is problematic for the global health workforce. Through a series of case studies, we then describe a model which enables institutions to compare themselves internally and with others internationally using bespoke or prioritised parameters rather than standards. The mobility of the global health workforce means that transportability of qualifications is an increasing area of concern. Valid qualifications based on workplace learning and assessment requires at least some variables to be benchmarked in order to judge performance.

  15. Transportability of tertiary qualifications and CPD: A continuing challenge for the global health workforce

    Directory of Open Access Journals (Sweden)

    Saltman Deborah C

    2012-07-01

    Full Text Available Abstract Background In workforces that are traditionally mobile and have long lead times for new supply, such as health, effective global indicators of tertiary education are increasingly essential. Difficulties with transportability of qualifications and cross-accreditation are now recognised as key barriers to meeting the rapidly shifting international demands for health care providers. The plethora of mixed education and service arrangements poses challenges for employers and regulators, let alone patients; in determining equivalence of training and competency between individuals, institutions and geographical locations. Discussion This paper outlines the shortfall of the current indicators in assisting the process of global certification and competency recognition in the health care workforce. Using Organisation for Economic Cooperation and Development (OECD data we highlight how International standardisation in the tertiary education sector is problematic for the global health workforce. Through a series of case studies, we then describe a model which enables institutions to compare themselves internally and with others internationally using bespoke or prioritised parameters rather than standards. Summary The mobility of the global health workforce means that transportability of qualifications is an increasing area of concern. Valid qualifications based on workplace learning and assessment requires at least some variables to be benchmarked in order to judge performance.

  16. Advanced examination techniques applied to the qualification of critical welds for the ITER correction coils

    Energy Technology Data Exchange (ETDEWEB)

    Sgobba, Stefano, E-mail: Stefano.Sgobba@cern.ch [CERN, CH-1211 Genève (Switzerland); Langeslag, Stefanie Agnes Elisabeth [CERN, CH-1211 Genève (Switzerland); Libeyre, Paul [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Marcinek, Dawid Jaroslaw [Tadeusz Kościuszko Cracow University of Technology, 31-155 Kraków (Poland); Piguiet, Aline [CERN, CH-1211 Genève (Switzerland); Cécillon, Alexandre [RX Solutions, ZAC Altaïs, Chavanod (France)

    2015-10-15

    Highlights: • X-ray computed tomography (CT) was successfully applied to inspect the full weld volume of critical qualification welds for the ITER correction coils. • These welds featuring a complex geometry are virtually uninspectable with sufficient resolution by conventional Non-Destructive Examination (NDE) techniques. • The applied advanced examinations allowed an exhaustive identification of weld imperfections and a thorough understanding of their nature, position and size. • A substantial progress in weld quality could be achieved during the weld qualification phases. - Abstract: The ITER correction coils (CCs) consist of three sets of six coils located in between the toroidal (TF) and poloidal field (PF) magnets. The CCs rely on a Cable-in-Conduit Conductor (CICC), whose supercritical cooling at 4.5 K is provided by helium inlets and outlets. The assembly of the nozzles to the stainless steel conductor conduit includes fillet welds requiring full penetration through the thickness of the nozzle. Static and cyclic stresses have to be sustained by the inlet welds during operation. The entire volume of helium inlet and outlet welds, that are submitted to the most stringent quality levels of imperfections according to standards in force, is virtually uninspectable with sufficient resolution by conventional or computed radiography or by Ultrasonic Testing. On the other hand, X-ray computed tomography (CT) was successfully applied to inspect the full weld volume of several dozens of helium inlet qualification samples. The extensive use of CT techniques allowed a significant progress in the weld quality of the CC inlets. CT is also a promising technique for inspection of qualification welds of helium inlets of the TF magnets, by far more complex to examine due to their larger dimensions.

  17. System qualification of Digital Detector Array (DDA)

    Energy Technology Data Exchange (ETDEWEB)

    Azeredo, Soraia R.; Oliveira, Davi F.; Nascimento, Joseilson R.; Lopes, Ricardo T., E-mail: soraia@lin.ufrj.br [Coordenacao dos Programas de Pos-Graducao em Engenharia (LIN/COPPE/UFRJ), Rio de Janeiro, RJ (Brazil). Lab. de Instrumentacao Nuclear

    2013-07-01

    Digital Detector Arrays (DDAs) should be characterized to establish the operating conditions of the system prior to perform a NDT (Nondestructive Testing). The image quality in digital radiography depends on the exposure conditions and the properties of the digital detectors. Quantitative definitions of DDA characterization parameters are important to discussions about achieved image quality of a particular type of DDA and also contribute to quantitative comparison of DDAs so that an appropriate digital detector is selected to meet NDT requirements. Evaluations of DDA factors were performed as defined by the standard practice for manufacturing characterization of DDAs, ASTM E2597-07. The evaluations provided quantitative results of some characteristic parameters. The factors evaluated were: basic spatial resolution, achievable contrast sensitivity, specific material thickness range and image lag. The results of measurements of characterization parameters are presented and related with the definitions in ASTM E2597-07. (author)

  18. The European teaching force: Conditions, mobility and qualifications

    Science.gov (United States)

    Smith, Janet

    1992-11-01

    Full realisation of the original aims of the EC — freedom of movement, services, capital and labour — coincides with an increasing focus on the role and function of teachers, on their supply and management and on their level of qualifications and expertise as the key to the provision of the high quality education provision which the new single Europe needs. As the largest occupational group within the EC with a pivotal position in the restructuring of education, lifelong learning and the management of human resources, teachers have come under the political spotlight. How they are selected, trained and qualified, what a government expects from their work and how their contribution to society is recognised and recompensed varies from country to country. This article provides basic facts on the conditions of service in the teaching forces in Member States and considers whether the Single Market principle can be extended to educational provision and teacher mobility in the light of evidence from the EC and the Nordic countries.

  19. 75 FR 1449 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-01-11

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... . Background On October 29, 2009, FMCSA published a notice of receipt of Federal diabetes exemption...

  20. 75 FR 14652 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-03-26

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemptions from the diabetes standard; request for comments. SUMMARY: FMCSA announces receipt of applications from 27 individuals for exemptions from the prohibition against persons with insulin- treated diabetes...

  1. 75 FR 13647 - Qualification of Drivers; Exemption Applications; Diabetes

    Science.gov (United States)

    2010-03-22

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemptions from the diabetes standard; request for comments. SUMMARY: FMCSA announces receipt of applications from 53 individuals for exemptions from the prohibition against persons with insulin- treated diabetes...

  2. 30 CFR 880.11 - Qualifications of projects.

    Science.gov (United States)

    2010-07-01

    ... ABANDONED MINE LAND RECLAMATION MINE FIRE CONTROL § 880.11 Qualifications of projects. The purpose of all... operating coal mines. Further, any such cooperative agreement that is entered into under the Energy Policy...

  3. The Influence of Age and Educational Qualification on Stakeholders ...

    African Journals Online (AJOL)

    info

    Cope and Ward (2002) reiterate that successful integration of learning technologies ... educational qualification influence the use digital tools for instructional delivery. ..... Education is too important a business to be entirely left in the hands of.

  4. 78 FR 63285 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... must provide for individual assessment of drivers with diabetes mellitus, and be consistent with the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  5. 78 FR 78479 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-12-26

    ... prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating commercial motor vehicles... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  6. 78 FR 63280 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  7. 78 FR 64267 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-28

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... diabetes mellitus, and be consistent with the criteria described in section 4018 of the Transportation... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  8. 76 FR 21792 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-04-18

    ... for exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces... insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  9. 78 FR 65034 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-30

    ... exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM) operating... drivers with diabetes mellitus, and be consistent with the criteria described in section 4018 of the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  10. 78 FR 56988 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-09-16

    ... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY: Federal Motor Carrier Safety Administration (FMCSA). ACTION: Notice of applications for...

  11. 75 FR 63536 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-10-15

    ... exemption from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  12. 78 FR 63295 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-10-23

    ... individuals for exemptions from the prohibition against persons with insulin- treated diabetes mellitus (ITDM... individual assessment of drivers with diabetes mellitus, and be consistent with the criteria described in... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes...

  13. PDSS/IMC qualification test software acceptance procedures

    Science.gov (United States)

    1984-01-01

    Tests to be performed for qualifying the payload development support system image motion compensator (IMC) are identified. The performance of these tests will verify the IMC interfaces and thereby verify the qualification test software.

  14. An investigation of individual functionality football referees qualifications

    Directory of Open Access Journals (Sweden)

    Berezka S.M.

    2014-11-01

    Full Text Available Purpose: determine the level of individual functionality referees qualifications. Objective of the study was to determine the physiological parameters characterizing the functionality of football referees qualifications. Material : mainly experiment involved 29 highly qualified referees aged 21-45 years. In the main experiment participated 29 referees and 40 assistant referees (n = 69 Ukrainian Premier League. Results: found that the means and methods that use Ukrainian football referee high qualification in the special physical training for a competition, are not effective enough. Consequence of poorly planned training process is to increase the number of wrong decisions of the referees during the match associated with poor motor activity. Conclusions: data obtained in the course of educational research confirmed our theory about the necessity of individualization process special physical training qualifications of referees, which would entail increasing the functional and motor abilities of the referees, and as a consequence of better and successful completion of the work.

  15. 23 CFR 650.309 - Qualifications of personnel.

    Science.gov (United States)

    2010-04-01

    ... personnel. (a) A program manager must, at a minimum: (1) Be a registered professional engineer, or have ten... leader. A team leader must, at a minimum: (1) Have the qualifications specified in paragraph (a) of this...

  16. Optimal qualifications, staffing and scope of practice for first responder nurses in disaster.

    Science.gov (United States)

    Yin, Huahua; He, Haiyan; Arbon, Paul; Zhu, Jingci; Tan, Jing; Zhang, Limei

    2012-01-01

    To explore: the selection criteria for first responder nurses during disaster; scope of practice for disaster relief nurses; appropriate nurse - medical practitioner ratio at the disaster site. Nurses are key members of disaster response medical teams. A scarcity of literature exists relating to nurses attending disasters, their qualifications, experience, scope of practice and appropriate staffing ratios. Qualitative and quantitative data were collected via survey using self-developed questionnaires. Participants were 95 medical workers, who participated in emergency rescue teams following the 2008 Wenchuan earthquake in China. A response rate of 93·7% achieved. The questionnaire included questions relating to nurses: previous experience in disaster relief; scope of practice at the disaster site; optimal ratio of medical practitioners to nurses in disaster relief teams. Following a disaster, first responder nurses considered most suitable were those with at least three years clinical experience, particularly in the emergency department or having emergency rescue skills training. The scope of practice for disaster relief nurses was different to that of nurses working in a hospital. The majority of participants reported insufficient nurses during the relief effort, concluding the optimal ratio of medical practitioner to nurse should range between 1:1-1:2 depending on the task and situation. At the scene of disaster, the preferred first responder nurses were nurses: with emergency rescue training; experienced in the emergency department; with at least three years clinical experience. The scope of practice for first responder nurses needs to be extended. Appropriate nurse - medical practitioner ratios in responding medical teams is dependant on the specific medical requirements of the disaster. The recommendations made by this study provide a guide to ensure that nurses can contribute effectively as essential members of first responder emergency disaster relief teams

  17. Preschool Teacher Candidates’ Research Qualifications and Anxiety Level towards Research

    OpenAIRE

    Konokman, Gamze Yavuz; Yelken, Tuğba; Yokuş, Gürol

    2015-01-01

    Problem StatementAcquisition of research qualifications are one of the most demanded learning outcomes of education faculties. There is great emphasis on building a research identity by developing the skills of students in education department faculties. However, very few surveys analyze the current situation of university students in the department of Early Childhood Education concerning research qualifications and anxiety level towards research.Purpose of StudyThis paper attempts to reveal ...

  18. ACADEMIC AND VOCATIONAL QUALIFICATIONS FOR SECONDARY VOCATIONAL EDUCATION GRADUATES

    Directory of Open Access Journals (Sweden)

    Svetlana А. Efimova

    2016-01-01

    Full Text Available The aim of the study is to provide scientific and methodological basis for competency-based assessment including differentiation between academic and vocational qualifications used for educational programs in teaching applied qualifications. Methods. The methods involve systematic activity and competency-based approaches, structural-functional analysis, analysis, generalization, benchmarking. Results. The issue of differentiation between qualifications, acquired by vocational education organizations graduates is carried out. The analysis is carried out according to two directions – academic and practice-oriented. It has become evident that the mentioned educational results have quite different customers.The role of the state as a customer of academic qualifications and a mediator between the labor market (its needs are expressed in professional standards and vocational education system is justified. An assessment sample is described. The sample includes two patterns of assessing the quality of education: vocational practice-oriented and academic assessment. Scientific novelty. Тhe sample of competency-based assessment in the system of vocational education is proved. The sample is designed to identify academic and vocational qualifications acquired by vocational education organizations graduates. The article specifies the definitions referring to the problem of qualifications assessment in the conditions of forming National qualifications system in the Russian Federation. Practical significance. The results of the research may be of some interest to researchers of applied qualifications, educators, specialists of educational authorities and vocational education institutions and can be used in modernization processes of regional assessment systems in vocational education. 

  19. Qualification Lab Testing on M1 Abrams Engine Oil Filters

    Science.gov (United States)

    2016-11-01

    TEST SYSTEM P/N: Flow Rate: GPM Element ID: Initial Volume: L Housing ID: Final Volume: L Element Type: Min. Element Bubble Point: in. H2O UPSTREAM...assemblies were assessed for qualification using the already qualified Purolator oil filter assembly as a baseline. 15. SUBJECT TERMS M-1, oil...HF28202 oil filter assemblies were assessed for qualification using the already qualified Purolator oil filter assembly as a baseline. The Donaldson

  20. Flight qualification of mortar-actuated parachute deployment systems

    Science.gov (United States)

    Pleasants, J. E.

    1975-01-01

    A brief discussion outlines background of mortar use in parachute deployment systems. A description of the system operation is presented. Effects of the environment on performance are discussed as well as the instrumentation needed to assess this performance. Power unit qualification and lot qualification for shear pins and cartridges is delineated. Functional mortar system tests are described. Finally, bridle deployment and parachute deployment are discussed.

  1. Assessment of the energy requirements and selected options facing major consumers within the Egyptian industrial and agricultural sectors. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1978-05-31

    The objectives of the energy assessment study of Egypt are to develop an understanding of the current status of the principal energy users in Egypt's industrial and agricultural sectors; to estimate the energy demand and efficiency for each selected subsector within these major sectors; to identify opportunities for fuel type changes, technology switches, or production pattern changes which might increase the efficiency with which Egypt's energy is used both now and in the future: and based on options identified, to forecast energy efficiencies for selected Egyptian subsectors for the years 1985 and 2000. Study results are presented for the iron and steel, aluminium, fertilizer, chemical, petrochemical, cement, and textile industries and automotive manufacturers. Study results for drainage, irrigation, and mechanization procedures in the agricultural sector and food processing sector are also presented. (MCW)

  2. [The biological component of the professional standards and qualification characteristics of preventive medicine specialists (as exemplified by the specialty of parasitology)].

    Science.gov (United States)

    Astanina, S Iu; Dovgalev, A S; Avdiukhina, T I

    2014-01-01

    In the context of theoretical analysis, the paper characterizes a specialist training system based on the biological component of the qualification characteristics and professional standard of preventive medicine specialists. Evidence is provided for the relationship between the components of the training system for preventive medicine specialists. The authors also specify the fact that the content of qualification characteristics and professional standards, besides general requirements, must take into account requirements for training the specialists in terms of natural and climatic and socioeconomic characteristics of regions.

  3. 36 CFR 1236.28 - What additional requirements apply to the selection and maintenance of electronic records storage...

    Science.gov (United States)

    2010-07-01

    ...., poor quality tape, high usage, poor environment, improper handling) must be read and corrected as... RECORDS MANAGEMENT ELECTRONIC RECORDS MANAGEMENT Additional Requirements for Electronic Records § 1236.28... magnetic computer tape media containing permanent and unscheduled records to identify any loss of data and...

  4. Concept selection for a planetary reflection-seismology system with multiple end-user requirements and mission constraints

    NARCIS (Netherlands)

    Batenburg, P.A.W.; Gill, E.K.A.; Drijkoningen, G.G.; Toxopeus, G.J.

    2010-01-01

    A study was performed to determine the feasibility of reflection seismology for planetary geology taking into account present-day technology advances. An approach based on end-user requirements was applied to assure the scientific usefulness of the results. Thirty applications of a

  5. Partial QoS-Aware Opportunistic Relay Selection Over Two-Hop Channels: End-to-End Performance Under Spectrum-Sharing Requirements

    KAUST Repository

    Yuli Yang,

    2014-10-01

    In this paper, we propose a partial quality-of-service (QoS)-oriented relay selection scheme with a decode-and-forward (DF) relaying protocol, to reduce the feedback amount required for relay selection. In the proposed scheme, the activated relay is the one with the maximum signal-to-noise power ratio (SNR) in the second hop among those whose packet loss rates (PLRs) in the first hop achieve a predetermined QoS level. For the purpose of evaluating the performance of the proposed scheme, we exploit it with transmission constraints imposed on the transmit power budget and interference to other users. By analyzing the statistics of received SNRs in the first and second hops, we obtain the end-to-end PLR of this scheme in closed form under the considered scenario. Moreover, to compare the proposed scheme with popular relay selection schemes, we also derive the closed-form PLR expressions for partial relay selection (PRS) and opportunistic relay selection (ORS) criteria in the same scenario under study. Illustrative numerical results demonstrate the accuracy of our derivations and substantiate that the proposed relay selection scheme is a promising alternative with respect to the tradeoff between performance and complexity.

  6. [Postdoctoral qualification regulations of medical faculties in German universities. A comparison of 1998 and 2010].

    Science.gov (United States)

    Knobloch, K; Sorg, H; Vogt, P M

    2012-05-01

    In Germany, Austria and Switzerland the "Habilitation" (postgraduate qualification) is currently the highest ranked university degree which qualifies candidates to perform high ranking autonomous research and teach the specific subject at university level. Although it is legally not an academic degree, the habilitation is a mandatory qualification for the later appointment and employment as a professor. The habilitation process is a complex assessment of diverse prerequisites which differ highly in terms of uniformity among the medical faculties in Germany. In order to re-evaluate these prerequisites and to find out if there might be more conformity for candidates all habilitation requirements were analyzed for 12 primary outcome measures according to Nagelschmidt and rated with a specific scoring system (Nagelschmidt score). The overall scoring for habilitation requirements increased from 15.2±5.1 points in 1998 to 21.9±4.0 points in 2010 (95% confidence interval 20.6-23.3, p<0.001, mainly due to increased requirements in terms of publications, teaching and mandatory board certification. No correlation was found between the number of habilitation degrees per faculty and the overall Nagelschmidt score (y=-0.0545x+26.021, r(2)=0,00028). The requirements for habilitation have substantially increased by 44% from 1998 to 2010 in Germany. This is mainly based on higher requirements in terms of publications, teaching and board certification.

  7. Airworthiness Qualification Criteria for Rotorcraft with External Sling Loads

    Science.gov (United States)

    Key, David L.

    2002-01-01

    This report presents the results of a study to develop airworthiness requirements for rotorcraft with external sling loads. The report starts with a review of the various phenomena that limit external sling load operations. Specifically discussed are the rotorcraft-load aeroservoelastic stability, load-on handling qualities, effects of automatic flight control system failure, load suspension system failure, and load stability at speed. Based on past experience and treatment of these phenomena, criteria are proposed to form a package for airworthiness qualification. The desired end objective is a set of operational flight envelopes for the rotorcraft with intended loads that can be provided to the user to guide operations in the field. The specific criteria proposed are parts of ADS-33E-PRF; MIL-F-9490D, and MIL-STD-913A all applied in the context of external sling loads. The study was performed for the Directorate of Engineering, U.S. Army Aviation and Missile Command (AMCOM), as part of the contract monitored by the Aerothermodynamics Directorate, U.S. Army AMCOM.

  8. CST receiver tube qualification, Phase 1, Investigation - Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Mack, I.; Rossy, J.-P.

    2010-05-15

    In this report the different application possibilities for concentrated solar thermal (CST) systems are studied. Further, the possible measuring methods for characterising and qualifying the receivers with their embedded absorber tubes are investigated. The investigations show that CST systems can be used as an environmentally friendly alternative to fossil fuels in many applications. The best known one is the generation of electrical power, but concentrated solar energy can also be used for desalination, industrial process heat, and for cooling of buildings. Industrial process heat is a large potential area with temperature in the range of 120 {sup o}C to over 400 {sup o}C. Heat below 400 {sup o}C can be provided by various parabolic trough and Fresnel systems, which are optimised for the temperature required. In order to further increase the usage of CST systems, it is of great importance to provide standards for the qualification and characterisation of the different components of the CST systems. Huge efforts are currently made to define a standard for evacuated receiver tubes. For the characterisation of the black absorber tubes the development is still at the beginning, although the need here is also given. (authors)

  9. Recommendations for fluorescence instrument qualification: the new ASTM Standard Guide.

    Science.gov (United States)

    DeRose, Paul C; Resch-Genger, Ute

    2010-03-01

    Aimed at improving quality assurance and quantitation for modern fluorescence techniques, ASTM International (ASTM) is about to release a Standard Guide for Fluorescence, reviewed here. The guide's main focus is on steady state fluorometry, for which available standards and instrument characterization procedures are discussed along with their purpose, suitability, and general instructions for use. These include the most relevant instrument properties needing qualification, such as linearity and spectral responsivity of the detection system, spectral irradiance reaching the sample, wavelength accuracy, sensitivity or limit of detection for an analyte, and day-to-day performance verification. With proper consideration of method-inherent requirements and limitations, many of these procedures and standards can be adapted to other fluorescence techniques. In addition, procedures for the determination of other relevant fluorometric quantities including fluorescence quantum yields and fluorescence lifetimes are briefly introduced. The guide is a clear and concise reference geared for users of fluorescence instrumentation at all levels of experience and is intended to aid in the ongoing standardization of fluorescence measurements.

  10. Seismic qualification of PWR plant auxiliary feedwater systems

    Energy Technology Data Exchange (ETDEWEB)

    Lu, S.C.; Tsai, N.C.

    1983-08-01

    The NRC Standard Review Plan specifies that the auxiliary feedwater (AFW) system of a pressurized water reactor (PWR) is a safeguard system that functions in the event of a Safe Shutdown Earthquake (SSE) to remove the decay heat via the steam generator. Only recently licensed PWR plants have an AFW system designed to the current Standard Review Plan specifications. The NRC devised the Multiplant Action Plan C-14 in order to make a survey of the seismic capability of the AFW systems of operating PWR plants. The purpose of this survey is to enable the NRC to make decisions regarding the need of requiring the licensees to upgrade the AFW systems to an SSE level of seismic capability. To implement the first phase of the C-14 plan, the NRC issued a Generic Letter (GL) 81-14 to all operating PWR licensees requesting information on the seismic capability of their AFW systems. This report summarizes Lawrence Livermore National Laboratory's efforts to assist the NRC in evaluating the status of seismic qualification of the AFW systems in 40 PWR plants, by reviewing the licensees' responses to GL 81-14.

  11. Qualifications, Discrimination, or Assimilation? An Extended Framework for Analysing Immigrant Wage Gaps

    DEFF Research Database (Denmark)

    Nielsen, Helena Skyt; Rosholm, Michael; Smith, Nina

    In this paper, we analyze immigrant wage gaps and propose an extension of the traditional wage decomposition technique, which is a synthesis from two strains of literature on ethnic/immigrant wage differences, namely the 'assimilation literature' and the 'discrimination literature'. We estimate...... separate wage equations for natives and a number of immigrant groups using panel data sample selection models. Based on the estimations, we find that the immigrant wage gap is caused by a lack of qualifications and incomplete assimilation, and that a large fraction of that gap would disappear if only...... immigrants could find employment and thus accumulate work experience....

  12. Qualifications, Discrimination, or Assimilation? An Extended Framework for Analysing Immigrant Wage Gaps

    DEFF Research Database (Denmark)

    Nielsen, Helena Skyt; Rosholm, Michael; Smith, Nina

    2001-01-01

    In this paper, we analyze immigrant wage gaps and propose an extension of the traditional wage decomposition technique, which is a synthesis from two strains of literature on ethnic/immigrant wage differences, namely the 'assimilation literature' and the 'discrimination literature'. We estimate...... separate wage equations for natives and a number of immigrant groups using panel data sample selection models. Based on the estimations, we find that the immigrant wage gap is caused by a lack of qualifications and incomplete assimilation, and that a large fraction of that gap would disappear if only...

  13. Referencing military service qualifications of the Republic of Lithuania to the Lithuanian qualifications framework

    OpenAIRE

    Liesionienė, Odeta; Nazelskis, Eugenijus; Tūtlys, Vidmantas

    2014-01-01

    Šiame straipsnyje tyrinėjamas Lietuvos Respublikos karių kvalifikacijų priskyrimas Lietuvos kvalifikacijų sandaros lygmenims. Straipsnio autorių siūloma karių kvalifikacijų susiejimo su Lietuvos kvalifikacijų sandara struktūra iš esmės padeda atskleisti karių kvalifikacijų lygmenų ypatumus ir skirtumus bei įvertinti šių kvalifikacijų atitikimą Lietuvos kvalifikacijų sandaros lygmenims. This paper analyses the issue of referencing military service qualifications of the Republic of Lithuania...

  14. RasGRP1, but not RasGRP3, is required for efficient thymic β-selection and ERK activation downstream of CXCR4.

    Directory of Open Access Journals (Sweden)

    Dominic P Golec

    Full Text Available T cell development is a highly dynamic process that is driven by interactions between developing thymocytes and the thymic microenvironment. Upon entering the thymus, the earliest thymic progenitors, called CD4(-CD8(- 'double negative' (DN thymocytes, pass through a checkpoint termed "β-selection" before maturing into CD4(+CD8(+ 'double positive' (DP thymocytes. β-selection is an important developmental checkpoint during thymopoiesis where developing DN thymocytes that successfully express the pre-T cell receptor (TCR undergo extensive proliferation and differentiation towards the DP stage. Signals transduced through the pre-TCR, chemokine receptor CXCR4 and Notch are thought to drive β-selection. Additionally, it has long been known that ERK is activated during β-selection; however the pathways regulating ERK activation remain unknown. Here, we performed a detailed analysis of the β-selection events in mice lacking RasGRP1, RasGRP3 and RasGRP1 and 3. We report that RasGRP1 KO and RasGRP1/3 DKO deficient thymi show a partial developmental block at the early DN3 stage of development. Furthermore, DN3 thymocytes from RasGRP1 and RasGRP1/3 double knock-out thymi show significantly reduced proliferation, despite expression of the TCRβ chain. As a result of impaired β-selection, the pool of TCRβ(+ DN4 is significantly diminished, resulting in inefficient DN to DP development. Also, we report that RasGRP1 is required for ERK activation downstream of CXCR4 signaling, which we hypothesize represents a potential mechanism of RasGRP1 regulation of β-selection. Our results demonstrate that RasGRP1 is an important regulator of proliferation and differentiation at the β-selection checkpoint and functions downstream of CXCR4 to activate the Ras/MAPK pathway.

  15. Team formation under normal versus crisis situations: leaders' assessments of task requirements and selection of team members

    OpenAIRE

    Baltos, Georgios; Mitsopoulou, Zoi

    2007-01-01

    MBA Professional Report The blend of skills, attributes, and relationships among team members influences their mutual performance. This project addressed the team composition requirements for tasks that vary in uncertainty, risk, and time pressure. Military leaders were asked to identify necessary team member attributes for strategy, negotiating, and crisis response teams, and to compose potential teams from among their colleagues for each scenario. Their responses were combined with ...

  16. It's not all about us: evolution and maintenance of Cryptococcus virulence requires selection outside the human host.

    Science.gov (United States)

    Gerstein, Aleeza C; Nielsen, Kirsten

    2017-04-01

    Cryptococcus is predominantly an AIDS-related pathogen that causes significant morbidity and mortality in immunocompromised patients. Research studies have historically focused on understanding how the organism causes human disease through the use of in vivo and in vitro model systems to identify virulence factors. Cryptococcus is not an obligate pathogen, however, as human-human transmission is either absent or rare. Selection in the environment must thus be invoked to shape the evolution of this taxa, and directly influences genotypic and trait diversity. Importantly, the evolution and maintenance of pathogenicity must also stem directly from environmental selection. To that end, here we examine abiotic and biotic stresses in the environment, and discuss how they could shape the factors that are commonly identified as important virulence traits. We identify a number of important unanswered questions about Cryptococcus diversity and evolution that are critical for understanding this deadly pathogen, and discuss how implementation of modern sampling and genomic tools could be utilized to answer these questions. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  17. Components Qualification for a Possible use in the Mu2e Calorimeter Waveform Digitizer

    Energy Technology Data Exchange (ETDEWEB)

    Di Falco, S. [INFN, Pisa; Donati, S. [INFN, Pisa; Morescalchi, L. [INFN, Pisa; Pedreschi, E. [INFN, Pisa; Pezzullo, G. [INFN, Pisa; Spinella, F. [INFN, Pisa

    2017-03-30

    The Mu2e experiment at Fermilab searches for the charged flavor violating conversion of a muon into an electron in the Coulomb field of a nucleus. The detector consists of a straw tube tracker and a CSI crystal electromagnetic calorimeter, both housed in a superconducting solenoid. Both the front-end and the digital electronics, located inside the cryostat, will be operated in vacuum under a 1 T magnetic field, having to sustain the high flux of neutrons and ionizing particles coming from the muons stopping target. These harsh experimental conditions make the design of the calorimeter waveform digitizer quite challenging. All the selected commercial devices must be tested individually and qualified for radiation hardness and operation in high magnetic field. At the moment the expected particles flux and spectra at the digitizers location are not completely simulated and we are using initial rough estimates to select the components for the first prototype. We are gaining experience in the qualification procedures using the selected components but the choice will be frozen only when dose and neutron flux simulations will be completed. The experimental results of the first qualification campaign are presented.

  18. Is a PhD a necessary requirement for lecturers in a`Medical School ...

    African Journals Online (AJOL)

    Background: Makerere University introduced a new policy1 on the minimum qualification for appointment to a lecturer teaching position and eligibility for subsequent promotions. The highlight of the policy is a requirement for a PhD or equivalent as the minimum qualification necessary for appointment to a lecturer position ...

  19. The receptor tyrosine kinase gene linotte is required for neuronal pathway selection in the Drosophila mushroom bodies.

    Science.gov (United States)

    Moreau-Fauvarque, C; Taillebourg, E; Boissoneau, E; Mesnard, J; Dura, J M

    1998-11-01

    The linotte (lio) mutant was first isolated as a memory mutant. The lio gene encodes a putative receptor tyrosine kinase (RTK), homologous to the human protein RYK. This gene has been independently identified in a screen for embryonic nervous system axonal guidance defects and called derailed (drl). Here, we report that linotte mutants present structural brain defects in the adult central complex (CX) and mushroom bodies (MB). linotte and derailed are allelic for this phenotype, which can be rescued by a drl+ transgene. The Lio RTK is expressed preferentially in the adult CX and MB. Our results suggest that, analogous to its role within the embryonic nervous system, the Lio RTK is involved in neuronal pathway selection during adult brain development. Copyright 1998 Elsevier Science Ireland Ltd. All Rights Reserved

  20. Development and Execution of a Large-scale DDT Tube Test for IHE Material Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Parker, Gary Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Broilo, Robert M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lopez-Pulliam, Ian Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Vaughan, Larry Dean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-24

    Insensitive High Explosive (IHE) Materials are defined in Chapter IX of the DOE Explosive Safety Standard (DOE-STD-1212-2012) as being materials that are massdetonable explosives that are so insensitive that the probability of accidental initiation or transition from burning to detonation is negligible1. There are currently a number of tests included in the standard that are required to qualify a material as IHE, however, none of the tests directly evaluate for the transition from burning to detonation (aka deflagration-to-detonation transition, DDT). Currently, there is a DOE complex-wide effort to revisit the IHE definition in DOE-STD-1212-2012 and change the qualification requirements. The proposal lays out a new approach, requiring fewer, but more appropriate tests, for IHE Material qualification. One of these new tests is the Deflagration-to-Detonation Test. According to the redefinition proposal, the purpose of the new deflagration-todetonation test is “to demonstrate that an IHE material will not undergo deflagration-to-detonation under stockpile relevant conditions of scale, confinement, and material condition. Inherent in this test design is the assumption that ignition does occur, with onset of deflagration. The test design will incorporate large margins and replicates to account for the stochastic nature of DDT events.” In short, the philosophy behind this approach is that if a material fails to undergo DDT in a significant over-test, then it is extremely unlikely to do so in realistic conditions. This effort will be valuable for the B61 LEP to satisfy their need qualify the new production lots of PBX 9502. The work described in this report is intended as a preliminary investigation to support the proposed design of an overly conservative, easily fielded DDT test for updated IHE Material Qualification standard. Specifically, we evaluated the aspects of confinement, geometry, material morphology and temperature. We also developed and tested a

  1. A Motor Drive Electronics Assembly for Mars Curiosity Rover: An Example of Assembly Qualification for Extreme Environments

    Science.gov (United States)

    Kolawa, Elizabeth; Chen, Yuan; Mojarradi, Mohammad M.; Tudryn Weber, Carissa

    2013-01-01

    In this paper, the technology development and infusion of the motor drive electronics assembly, along with the technology qualification and space qualification, is described and detailed. The process is an example of the qualification methodology for extreme environmen

  2. Transfer of training and simulator qualification or myth and folklore in helicopter simulation

    Science.gov (United States)

    Dohme, Jack

    1992-01-01

    Transfer of training studies at Fort Rucker using the backward-transfer paradigm have shown that existing flight simulators are not entirely adequate for meeting training requirements. Using an ab initio training research simulator, a simulation of the UH-1, training effectiveness ratios were developed. The data demonstrate it to be a cost-effective primary trainer. A simulator qualification method was suggested in which a combination of these transfer-of-training paradigms is used to determine overall simulator fidelity and training effectiveness.

  3. Qualification of a Glassy Carbon Blade for a LHC Fast Vacuum Valve

    CERN Document Server

    Garion, C

    2013-01-01

    To protect sensitive LHC machine systems against an unexpected gas inrush, a fast vacuum valve system is under development at CERN. The design of the shutter has to be compatible with dynamic loads occurring during the fast closure, namely in the 20 ms range. The material has to fulfil all main requirements such as transparency, high melting temperature, dust free and adequate leak tightness. A development of a blade in vitreous carbon material has been carried out at CERN. The blade has been successfully integrated in a commercial pendulum fast valve. In this paper, the vacuum and mechanical qualification tests are presented.

  4. Problems and Tasks of TRAINING at Courses for Enhancement of Qualification in the Radioactive Waste Management Area

    Energy Technology Data Exchange (ETDEWEB)

    Sobolev, I. A.; Dmitriev, S. A.; Batyukhnova, O. G.; Shcherbatova, T. D.; Ojovan, M. I.; Arustamov, A. E.

    2002-02-25

    Requirements to the professional competence of the personnel engaged in the area of the radioactive waste management are increased. Higher school cannot supply the branch with the qualified personnel; therefore special attention should be given to the system of staff retraining and to the increase of their qualification. In that paper the analysis of SIA ''Radon'' experience on the organization and carrying out training at courses of qualification improvement is represented. The main criterion of the analysis is the research of an education efficiency. Also here the basic directions of the training process improving are submitted as well as the requirements that should be considered when forming the teaching staff and trainees groups.

  5. Background information for NDT qualification of Finnish disposal canisters of spent fuel

    Energy Technology Data Exchange (ETDEWEB)

    Sarkimo, M. [VTT Technical Research Centre of Finland, Espoo (Finland); Pitkaenen, J.

    2013-12-15

    This report presents a review to basic concepts, which are applied in the qualification of non-destructive testing (NDT) techniques. The qualification systems developed and used in some countries are briefly described in the beginning of the report. Anyway the report mainly discusses the qualification practices applied in the Finnish nuclear industry. The Finnish Radiation and Nuclear Safety Authority (STUK) in the YVL Guide 3.8 define the Finnish qualification approach applied for the in-service inspections. The principles presented in this document follow the views of the international organisations: Nuclear Regulator Working Group (NRWG) and European Network for Inspection and Qualification (ENIQ). For the practical qualification work a national guideline is established using so called SP-documents that include specific rules and instructions for execution of qualifications in accordance with YVL Guide 3.8 principles. Altogether the Finnish qualification system can be seen very well to follow the European (ENIQ) methodology. The report discusses several qualification terms and documents. Thus the normally necessary tasks and parts of a qualification are described. The qualification can be seen as a project that includes several tasks, which will be performed by different parties. Enough resources and time should be reserved for the planning and control of a qualification project to ensure its fluent progress. Some tasks are discussed in the report taking into account the situation in the qualification cases that are seen to be linked to the inspections of disposal canisters of spent fuel. (orig.)

  6. Open-Source RTOS Space Qualification: An RTEMS Case Study

    Science.gov (United States)

    Zemerick, Scott

    2017-01-01

    NASA space-qualification of reusable off-the-shelf real-time operating systems (RTOSs) remains elusive due to several factors notably (1) The diverse nature of RTOSs utilized across NASA, (2) No single NASA space-qualification criteria, lack of verification and validation (V&V) analysis, or test beds, and (3) different RTOS heritages, specifically open-source RTOSs and closed vendor-provided RTOSs. As a leader in simulation test beds, the NASA IV&V Program is poised to help jump-start and lead the space-qualification effort of the open source Real-Time Executive for Multiprocessor Systems (RTEMS) RTOS. RTEMS, as a case-study, can be utilized as an example of how to qualify all RTOSs, particularly the reusable non-commercial (open-source) ones that are gaining usage and popularity across NASA. Qualification will improve the overall safety and mission assurance of RTOSs for NASA-agency wide usage. NASA's involvement in space-qualification of an open-source RTOS such as RTEMS will drive the RTOS industry toward a more qualified and mature open-source RTOS product.

  7. Important behavioral traits for predicting guide dog qualification.

    Science.gov (United States)

    Arata, Sayaka; Momozawa, Yukihide; Takeuchi, Yukari; Mori, Yuji

    2010-05-01

    Guide dogs for the blind help blind people physically and mentally in their daily lives. Their qualifications are based on health, working performance and temperament; approximately 70% of dogs that fail to qualify are disqualified for behavioral reasons. In order to achieve early prediction of qualification, it would be essential as the first step to identify important temperament traits for guide dogs. Therefore, we administered a questionnaire consisting of 22 temperament items to experienced trainers to assess candidate dogs at the Japan Guide Dog Association after three months of training, which was at least three months prior to the final success (qualified as a guide dog) or failure (disqualified for behavioral reasons) judgment. Factor analyses of question items stably extracted three factors with high internal consistency, Distraction, Sensitivity and Docility. When we compared factor points between successful dogs and failed dogs, the successful dogs showed significantly and consistently lower Distraction points and higher Docility points. Additionally, Distraction points could predict qualification with 80.6% accuracy and detect 28.2% of the failed dogs that had higher Distraction points than any of the successful dogs. Of the nine question items not included in the three factors, two items (;Aggression' and ;Animal interest') were consistently associated with qualification. These results suggest that Distraction is stably assessable and has the strongest impact on success or failure judgment; therefore, it will be the first target to establish a behavioral test that may lead to early prediction of guide dog qualification.

  8. Strategy for an abbreviated in-house qualification of a commercially available Rapid Microbiology Method (RMM) for canadian regulatory approval.

    Science.gov (United States)

    Chisholm, Jolene; Bhatt, Shashank; Chaboureau, Amélie; Viswanathan, Sowmya

    2017-12-01

    Cell therapy products (CTP) typically require full sterility, endotoxin and Mycoplasma testing before product release. Often this is not feasible with fresh cells, and sponsors may rely on rapid microbiological methods (RMM). RMM must be qualified in-house using the sponsor's facilities, equipment, consumables, cells and matrices to meet regulatory approval. Herein, we present a cost-effective strategy to conduct an in-house abbreviated qualification of a commercially available RMM kit to meet Health Canada regulatory requirements. We performed an abbreviated qualification using a polymerase chain reaction (PCR)-based Mycoplasma testing method involving assay sensitivity and ruggedness, based on an experimental plan that was pre-approved by Health Canada. Briefly, investigational CTPs were tested in-house using a PCR-based Mycoplasma detection kit. Assay sensitivity was determined using a 10-fold dilution series of genomic DNA of only two Mycoplasma species, Mycoplasma arginini and Mycoplasma hominis in the absence of CTP-matrix as the kit had been previously validated against nine species. Matrix interference was measured by testing independent CTP samples. Testing by different operators on different days measured ruggedness. The RMM Mycoplasma qualification exceeded sensitivity (4 genome copies per reaction for M. arginini and 0.12 genome copies per reaction for M. hominis) and met ruggedness requirements without matrix interference, as required by the Pharmacopoeial guidelines (Ph. Eur. 2.6.7 and USP ). Our approach represents a minimal qualification that can be performed by an academic institution while ensuring regulatory compliance for implementing RMM testing for in-process and product-release testing of CTPs. Copyright © 2017 International Society for Cellular Therapy. Published by Elsevier Inc. All rights reserved.

  9. Seismic Qualification Program Plan for continued operation at DOE-SRS Nuclear Material Processing facilities

    Energy Technology Data Exchange (ETDEWEB)

    Talukdar, B.K.; Kennedy, W.N.

    1991-12-31

    The Savannah River Facilities for the most part were constructed and maintained to standards that were developed by Du Pont and are not rigorously in compliance with the current General Design Criteria (GDC); DOE Order 6430.1A requirements. In addition, any of the facilities were built more than 30 years ago, well before DOE standards for design were issued. The Westinghouse Savannah River Company (WSRC) has developed a program to address the evaluation of the Nuclear Material Processing (NMP) facilities to GDC requirements. The program includes a facility base-line review, assessment of areas that are not in compliance with the GDC requirements, planned corrective actions or exemptions to address the requirements, and a safety assessment. The authors from their direct involvement with the Program, describe the program plan for seismic qualification including other natural phenomena hazards for existing NMP facility structures to continue operation. Professionals involved in similar effort at other DOE facilities may find the program useful.

  10. Seismic Qualification Program Plan for continued operation at DOE-SRS Nuclear Material Processing facilities

    Energy Technology Data Exchange (ETDEWEB)

    Talukdar, B.K.; Kennedy, W.N.

    1991-01-01

    The Savannah River Facilities for the most part were constructed and maintained to standards that were developed by Du Pont and are not rigorously in compliance with the current General Design Criteria (GDC); DOE Order 6430.1A requirements. In addition, any of the facilities were built more than 30 years ago, well before DOE standards for design were issued. The Westinghouse Savannah River Company (WSRC) has developed a program to address the evaluation of the Nuclear Material Processing (NMP) facilities to GDC requirements. The program includes a facility base-line review, assessment of areas that are not in compliance with the GDC requirements, planned corrective actions or exemptions to address the requirements, and a safety assessment. The authors from their direct involvement with the Program, describe the program plan for seismic qualification including other natural phenomena hazards for existing NMP facility structures to continue operation. Professionals involved in similar effort at other DOE facilities may find the program useful.

  11. Navy theater ballistic missile defense boost multispectral discrimination requirements for low-resolution detection, classification, and high-resolution aimpoint selection

    Science.gov (United States)

    Paiva, Clifford A.

    1998-03-01

    The U.S. Navy has been requested to provide insightful responses to questions regarding low and high resolution target discrimination and target classification capabilities for short and medium range ballistic missiles (SRBM/MRBM). Specific targets studied for this paper include the solid booster and the associated attitude control system (ACS) liquid divert thruster systems. Discriminants selected include booster and ACS separation debris, as well as fuel vent phenomena. Debris and vent cloud containment and elimination through Gaussian suppression techniques have been implemented for low resolution assessment for target detection and tracking. Target gradient edge intensities were extracted for aimpoint selection and will be added to the pattern referencing library database at NSWC. The results of this study indicate an increasing requirement for advanced image processing on the focal plane array of a generic LEAP (light exo-atmospheric projectile) type kill kinetic vehicle (KKV) in order to implement effective target and aimpoint detection/tracking correlation matching routines.

  12. Identification and Qualification of the Efficiency of Processes in a chosen Enterprise

    OpenAIRE

    Dobešová, Markéta

    2008-01-01

    I identificated of processes in company ENVINET a.s. and made proposal qualification of the efficiency of processes. I applied to indicators of the efficiency of processes. I recommended new possibilities qualification of the efficiency of processes.

  13. Using the Laser Marksmanship Training System to Predict Rifle Marksmanship Qualification

    National Research Council Canada - National Science Library

    Smith, Monte

    2003-01-01

    ...) and live-fire-based rifle marksmanship performance, 186 Reserve Component (RC) soldiers from Idaho and Oregon fired for qualification on a scaled LMTS version and live-fire version of the Army's standard pop-up target qualification course...

  14. Importance of the European qualification frame (EQF) and its tools for radiation protection; Bedeutung des Europaeischen Qualifikationsrahmens (EQR) und seiner Instrumente fuer den Strahlenschutz

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt-Hannig, Annemarie [Bundesamt fuer Strahlenschutz, Oberschleissheim (Germany). Fachbereich Strahlenschutz und Gesundheit

    2013-09-01

    The harmonization of different radiation protection education and training systems in Europe and the mutual approval of the qualifications acquired abroad are discussed since years. Due to large national differences the mutual approval is usually based on case approaches instead of a standardized procedure. With the European qualification frame for life learning and EVCET (European credit system for vocational education and training) there are tools that could also be used in the sector of radiation protection education and training. The draft of the EURATOM basic safety standards (BSS) guideline includes the requirement of an approval of radiation protection officer certifications.

  15. Qualifications Frameworks and their conflicting social imaginaries of globalisation

    DEFF Research Database (Denmark)

    Sarauw, Laura Louise

    2013-01-01

    Critics of the European Bologna process often see it as a univocal standardization of higher education. By exploring how different qualifications frameworks currently project unlike imaginaries of and responses to globalisation, this article takes a different stance. As a key point, I argue...... that the well-known imaginary of globalisation as a change towards a more diverse and unforeseeable world, which calls for the development of flexible, lifelong learners with a broad knowledge base and strong democratic competencies that we find in the overarching qualifications framework of the Bologna process......, is a highly contested imaginary. In contrast, for example, the Danish qualifications framework of 2003 projects an imaginary of globalisation as a change towards a smaller and more predictable world, which enables a novel and more efficient alignment of the curriculum towards specific professional needs...

  16. Issues in the flight qualification of a space power reactor

    Science.gov (United States)

    Polansky, G. F.; Schmidt, G. L.; Voss, S. S.; Reynolds, E. L.

    1994-09-01

    This paper presents an overview of the Nuclear Electric Propulsion Space Test Program (NEPSTP). The program goals, the proposed mission, the spacecraft, and the Topaz II space nuclear power system are described. The subject of flight qualification is examined and the inherent difficulties of qualifying a space reactor are described. The differences between US and Russian flight qualification procedures are explored. A plan is then described that was developed to determine an appropriate flight qualification program for the Topaz II reactor to support a possible NEPSTP launch. Refocusing of the activities of the Ballistic Missile Defense Organization (BMDO), combined with budgetary pressures, forced the cancellation of the NEPSTP at the end of the 1993 fiscal year.

  17. Professional qualifications and accreditation of courses in librarianship

    Directory of Open Access Journals (Sweden)

    Melita Ambrožič

    1997-01-01

    Full Text Available The contribution presents the difference between the system of attaining professional qualifications in Slovenia and the existent praxis in some anglo-american countries, where professional examinations - as an element of control of the entry into the librarian profession - have been superseded with accreditation of the educational programmes and special criteria for acquiring initial qualification.The accreditation procedure is described, as well as the role of library associa tions,both in the control of the quality of the regular and permanent education of librarians. The author asks herself if the conditions in Slovenia permit the change of professional qualification attaining system and its gradual approaching to the anglo-american model.

  18. AZ-101 Mixer Pump Test Qualification Test Procedures (QTP)

    Energy Technology Data Exchange (ETDEWEB)

    THOMAS, W.K.

    2000-01-10

    Describes the Qualification test procedure for the AZ-101 Mixer Pump Data Acquisition System (DAS). The purpose of this Qualification Test Procedure (QTP) is to confirm that the AZ-101 Mixer Pump System has been properly programmed and hardware configured correctly. This QTP will test the software setpoints for the alarms and also check the wiring configuration from the SIMcart to the HMI. An Acceptance Test Procedure (ATP), similar to this QTP will be performed to test field devices and connections from the field.

  19. Hanford Waste Vitrification Plant Project Waste Form Qualification Program Plan

    Energy Technology Data Exchange (ETDEWEB)

    Randklev, E.H.

    1993-06-01

    The US Department of Energy has created a waste acceptance process to help guide the overall program for the disposal of high-level nuclear waste in a federal repository. This Waste Form Qualification Program Plan describes the hierarchy of strategies used by the Hanford Waste Vitrification Plant Project to satisfy the waste form qualification obligations of that waste acceptance process. A description of the functional relationship of the participants contributing to completing this objective is provided. The major activities, products, providers, and associated scheduling for implementing the strategies also are presented.

  20. Qualification paths of adult educators in Sweden and Denmark

    DEFF Research Database (Denmark)

    Andersson, Per; Köpsén, Susanne; Larson, Anne

    2013-01-01

    fields of education and training. In this study, we analyse the qualification paths, or learning trajectories, of prospective adult educators in Sweden and Denmark. The analysis is based on narrative interviews with 29 students in training to become adult educators. The career paths of adult educators...... and the relation to the learners is part of the professional development. Finally, we argue that both academic studies and hands-on work in the adult education community are crucial parts of the adult educator’s qualification path....

  1. Qualification of the FORMOSA software at Electricite de France

    Energy Technology Data Exchange (ETDEWEB)

    Engrand, P.; Marginier, A.M.; Rosset, F.D.; Wong, H.I.; Roulier, B.; Bartro, V.; Aragones, V

    1998-12-31

    The FORMOSA software, dedicated to fuel management optimization, is under qualification at Electricite de France. The LOOP software which allows FORMOSA to be used in the EDF context has been developed. In particular, it includes a module that generates cross-section input files for FORMOSA and the EDF official neutronic diffusion code, COCCINELLE, that validates the optimized loading patterns found by FORMOSA. Version 2.0 of LOOP is giving satisfactory results on all the fuel management modes used at EDF. The results of the qualification and the features of the software are presented, future prospects are outlined. (author) 6 refs.

  2. Sensor Data Qualification Technique Applied to Gas Turbine Engines

    Science.gov (United States)

    Csank, Jeffrey T.; Simon, Donald L.

    2013-01-01

    This paper applies a previously developed sensor data qualification technique to a commercial aircraft engine simulation known as the Commercial Modular Aero-Propulsion System Simulation 40,000 (C-MAPSS40k). The sensor data qualification technique is designed to detect, isolate, and accommodate faulty sensor measurements. It features sensor networks, which group various sensors together and relies on an empirically derived analytical model to relate the sensor measurements. Relationships between all member sensors of the network are analyzed to detect and isolate any faulty sensor within the network.

  3. Qualification Procedures of the CMS Pixel Barrel Modules

    CERN Document Server

    Starodumov, A; Horisberger, R.; Kastli, H.Chr.; Kotlinski, D.; Langenegger, U.; Meier, B.; Rohe, T.; Trueb, P.

    2006-01-01

    The CMS pixel barrel system will consist of three layers built of about 800 modules. One module contains 66560 readout channels and the full pixel barrel system about 48 million channels. It is mandatory to test each channel for functionality, noise level, trimming mechanism, and bump bonding quality. Different methods to determine the bump bonding yield with electrical measurements have been developed. Measurements of several operational parameters are also included in the qualification procedure. Among them are pixel noise, gains and pedestals. Test and qualification procedures of the pixel barrel modules are described and some results are presented.

  4. 42 CFR 410.77 - Certified nurse-midwives' services: Qualifications and conditions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Certified nurse-midwives' services: Qualifications... Medical and Other Health Services § 410.77 Certified nurse-midwives' services: Qualifications and conditions. (a) Qualifications. For Medicare coverage of his or her services, a certified nurse-midwife must...

  5. Global National Qualifications Framework Inventory: Country Cases from EU and ETF Partner Countries

    Science.gov (United States)

    Cedefop - European Centre for the Development of Vocational Training, 2013

    2013-01-01

    Certificates, diplomas and titles are commonly known as qualifications. Their purpose is to show employers, training providers, and individuals what the person holding the qualification has learned and can do. Every country issues many different qualifications, but for the European labor market to work as intended--that is for European citizens to…

  6. Global Inventory of Regional and National Qualifications Frameworks. Volume II: National and Regional Cases

    Science.gov (United States)

    UNESCO Institute for Lifelong Learning, 2015

    2015-01-01

    This second volume of the "Global Inventory of Regional and National Qualifications Frameworks" focuses on national and regional cases of national qualifications frameworks for eighty- six countries from Afghanistan to Uzbekistan and seven regional qualifications frameworks. Each country profile provides a thorough review of the main…

  7. 29 CFR 1604.2 - Sex as a bona fide occupational qualification.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Sex as a bona fide occupational qualification. 1604.2... GUIDELINES ON DISCRIMINATION BECAUSE OF SEX § 1604.2 Sex as a bona fide occupational qualification. (a) The commission believes that the bona fide occupational qualification exception as to sex should be interpreted...

  8. 75 FR 9905 - Guidance for Industry: Characterization and Qualification of Cell Substrates and Other Biological...

    Science.gov (United States)

    2010-03-04

    ...: Characterization and Qualification of Cell Substrates and Other Biological Materials Used in the Production of... vaccines for the characterization and qualification of cell substrates, viral seeds, and other biological...: Characterization and Qualification of Cell Substrates and Other Biological Materials Used in the Production of...

  9. Water/Wastewater Treatment Plant Operator Qualifications.

    Science.gov (United States)

    Water and Sewage Works, 1979

    1979-01-01

    This article summarizes in tabular form the U.S. and Canadian programs for classification of water and wastewater treatment plant personnel. Included are main characteristics of the programs, educational and experience requirements, and indications of requirement substitutions. (CS)

  10. Optimizing the NPP refurbishment environmental qualification design process for an in-service installation

    Energy Technology Data Exchange (ETDEWEB)

    MacBeth, M.J.; Hemmings, R.L. [Canatom-NPM, Oakville, Ontario (Canada)

    2002-07-01

    This paper describes the Environmental Qualification (EQ) modification design work required to upgrade the Reactor Building (RB) airlocks at the Pickering Nuclear Generating Station B Facility. The RB airlocks provide a containment boundary function and are designed to prevent a breach of containment from occurring for all analysed station conditions. Recent, more stringent, Canadian Nuclear Regulatory actions have imposed EQ requirements for the RB airlocks in Canadian Nuclear Generating Stations. The airlocks are required to function under the worst-case design basis accident (DBA) conditions for the assigned mission duration and the design must demonstrate that a spurious door opening cannot be initiated by any accident conditions. This paper reviews key project design activities while providing detailed insights to the potential solution or elimination of some problematic aspects of these types of design activities. General recommendations for optimal technical management of such project implementation issues are presented. (author)

  11. Optimizing trial design in pharmacogenetics research: comparing a fixed parallel group, group sequential, and adaptive selection design on sample size requirements.

    Science.gov (United States)

    Boessen, Ruud; van der Baan, Frederieke; Groenwold, Rolf; Egberts, Antoine; Klungel, Olaf; Grobbee, Diederick; Knol, Mirjam; Roes, Kit

    2013-01-01

    Two-stage clinical trial designs may be efficient in pharmacogenetics research when there is some but inconclusive evidence of effect modification by a genomic marker. Two-stage designs allow to stop early for efficacy or futility and can offer the additional opportunity to enrich the study population to a specific patient subgroup after an interim analysis. This study compared sample size requirements for fixed parallel group, group sequential, and adaptive selection designs with equal overall power and control of the family-wise type I error rate. The designs were evaluated across scenarios that defined the effect sizes in the marker positive and marker negative subgroups and the prevalence of marker positive patients in the overall study population. Effect sizes were chosen to reflect realistic planning scenarios, where at least some effect is present in the marker negative subgroup. In addition, scenarios were considered in which the assumed 'true' subgroup effects (i.e., the postulated effects) differed from those hypothesized at the planning stage. As expected, both two-stage designs generally required fewer patients than a fixed parallel group design, and the advantage increased as the difference between subgroups increased. The adaptive selection design added little further reduction in sample size, as compared with the group sequential design, when the postulated effect sizes were equal to those hypothesized at the planning stage. However, when the postulated effects deviated strongly in favor of enrichment, the comparative advantage of the adaptive selection design increased, which precisely reflects the adaptive nature of the design. Copyright © 2013 John Wiley & Sons, Ltd.

  12. Development and Commissioning Results of the Hybrid Sensor Bus Engineering Qualification Model

    Science.gov (United States)

    Hurni, Andreas; Putzer, Phillipp; Roner, Markus; Gurster, Markus; Hulsemeyer, Christian; Lemke, Norbert M. K.

    2016-08-01

    In order to reduce mass, AIT effort and overall costs of classical point-to-point wired temperature sensor harness on-board spacecraft OHB System AGhas introduced the Hybrid Sensor Bus (HSB) system which interrogates sensors connected in a bus architecture. To use the advantages of electrical as wellas of fiber-optical sensing technologies, HSB is designed as a modular measurement system interrogating digital sensors connected on electricalsensor buses based on I2C and fiber-optical sensor buses based on fiber Bragg grating (FBG) sensors inscribed in optical fibers. Fiber-optical sensor bus networks on-board satellites are well suited for temperature measurement due to low mass, electro-magnetic insensitivity and the capability to embed them inside structure parts. The lightweight FBG sensors inscribed in radiation tolerant fibers can reach every part of the satellite. HSB has been developed in the frame of the ESA ARTES program with European and German co- funding and will be verified as flight demonstrator on- board the German Heinrich Hertz satellite (H2Sat).In this paper the Engineering Qualification Model (EQM) development of HSB and first commissioning results are presented. For the HSB development requirements applicable for telecommunication satellite platforms have been considered. This includes an operation of at least 15 years in a geostationary orbit.In Q3/2016 the qualification test campaign is planned to be carried out. The HSB EQM undergoes a full qualification according to ECSS. The paper concludes with an outlook regarding this HSB flight demonstrator development and its in-orbit verification (IOV) on board H2Sat.

  13. Qualification of a Method to Calculate the Irrecoverable Pressure Loss in High Reynolds Number Piping Systems

    Energy Technology Data Exchange (ETDEWEB)

    Sigg, K. C.; Coffield, R. D.

    2002-09-01

    High Reynolds number test data has recently been reported for both single and multiple piping elbow design configurations at earlier ASME Fluid Engineering Division conferences. The data of these studies ranged up to a Reynolds number of 42 x 10[sup]6 which is significantly greater than that used to establish design correlations before the data was available. Many of the accepted design correlations, based on the lower Reynolds number data, date back as much as fifty years. The new data shows that these earlier correlations are extremely conservative for high Reynolds number applications. Based on the recent high Reynolds number information a new recommended method has been developed for calculating irrecoverable pressure loses in piping systems for design considerations such as establishing pump sizing requirements. This paper describes the recommended design approach and additional testing that has been performed as part of the qualification of the method. This qualification testing determined the irrecoverable pressure loss of a piping configuration that would typify a limiting piping section in a complicated piping network, i.e., multiple, tightly coupled, out-of-plane elbows in series under high Reynolds number flow conditions. The overall pressure loss measurements were then compared to predictions, which used the new methodology to assure that conservative estimates for the pressure loss (of the type used for pump sizing) were obtained. The recommended design methodology, the qualification testing and the comparison between the predictions and the test data are presented. A major conclusion of this study is that the recommended method for calculating irrecoverable pressure loss in piping systems is conservative yet significantly lower than predicted by early design correlations that were based on the extrapolation of low Reynolds number test data.

  14. Organisational approaches to the 'professionalisation' agenda: planning the provision of the new ITE qualifications for the FE sector

    Directory of Open Access Journals (Sweden)

    Broad, Janet

    2010-01-01

    Full Text Available Situated within the context of policy change in the Lifelong Learning Sector, this article is based on the LONCETT (London Centre for Excellence in Teacher Training research strand exploring organisational responses to policy challenges and the impacts on the delivery of Initial Teacher Education (ITE for the sector. It builds on and further develops three themes reported in year one (Wooding, 2007: impact of the new requirements for QTLS/ATLS; impact on delivery patterns and organisational collaboration; and organisational responses to existing staff first employed prior to 2007. Findings suggest a positive view of the new qualifications in terms of enhancement of teachers’ professional standing. Nevertheless, the introduction of three levels of qualification: preparing to teach, certificate, and diploma in teaching have caused confusion, especially in light of the proliferation of job specifications, titles and practices within Further Education (FE noted by Gleeson, Davies and Wheeler (2005.

  15. Qualification of the First ICS-3000 ION Chromatograph for use at the Defense Waste Processing Facility

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, T; Mahannah, R.

    2011-07-05

    The ICS-3000 Ion Chromatography (IC) system installed in 221-S M-13 has been qualified for use. The qualification was a head to head comparison of the ICS-3000 with the currently used DX-500 IC system. The crosscheck work included standards for instrument calibration and calibration verifications and standards for individual anion analysis, where the standards were traceable back to the National Institute of Standards and Technology (NIST). In addition the crosscheck work included the analysis of simulated Sludge Receipt Adjustment Tank (SRAT) Receipt, SRAT Product, and Slurry Mix Evaporator (SME) samples, along with radioactive Sludge Batch 5 material from the SRAT and SME tanks. Based upon the successful qualification of the ICS-3000 in M-13, it is recommended that this task proceed in developing the data to qualify, by a head to head comparison of the two ICS-3000 instruments, a second ICS-3000 to be installed in M-14. The Defense Waste Processing Facility (DWPF) requires the analysis of specific anions at various stages of its processing of high level waste (HLW). The anions of interest to the DWPF are fluoride, formate, chloride, nitrite, nitrate, sulfate, oxalate, and phosphate. The anion analysis is used to evaluate process chemistry including formic acid/nitric acid additions to establish optimum conditions for mercury stripping, reduction-oxidation (REDOX) chemistry for the melter, nitrite destruction, organic acid constituents, etc. The DWPF Laboratory (Lab) has been using Dionex DX-500 ion chromatography (IC) systems since 1998. The vendor informed DWPF in 2006 that the instruments would no longer be supported by service contracts after 2008. DWPF purchased three new ICS-3000 systems in September of 2006. The ICS-3000 instruments are (a) designed to be more stable using an eluent generator to make eluent, (b) require virtually no daily chemical handling by the analysts, (c) require less line breaks in the hood, and (d) generally require less maintenance

  16. 76 FR 37171 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-06-24

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in.../2008/pdf/E8-785.pdf . Background On May 5, 2011, FMCSA published a notice of receipt of Federal...

  17. 77 FR 43417 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-07-24

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in.../2008/pdf/E8-785.pdf . Background On June 6, 2012, FMCSA published a notice of receipt of Federal...

  18. 75 FR 57329 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-09-20

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . Background On July 21, 2010, FMCSA published a...

  19. 75 FR 64394 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-10-19

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . Background On August 27, 2010, FMCSA published a...

  20. 78 FR 19798 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-04-02

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in.../FR-2010-12-29/pdf/2010-32876.pdf . Background On February 4, 2013, FMCSA published a notice of...

  1. 76 FR 72031 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-11-21

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate... January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . FOR...

  2. 77 FR 13685 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-03-07

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in.../2008/pdf/E8-785.pdf . Background On January 24, 2012, FMCSA published a notice of receipt of Federal...

  3. 77 FR 20874 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-04-06

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in.../2008/pdf/E8-785.pdf . Background On February 22, 2012, FMCSA published a notice of receipt of Federal...

  4. 77 FR 33554 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-06

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... individuals for exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM... you may visit http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . FOR FURTHER INFORMATION CONTACT...

  5. 76 FR 7625 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-02-10

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... prohibiting persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles... http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . Background On December 23, 2010, FMCSA published a...

  6. 76 FR 61139 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2011-10-03

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... prohibiting persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles... http://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . Background On August 4, 2011, FMCSA published a...

  7. 77 FR 33551 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-06-06

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating commercial motor vehicles... Federal Register on January 17, 2008 (73 FR 3316), or you may visit http://edocket.access.gpo.gov/2008/pdf...

  8. 77 FR 27842 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-05-11

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... exemption from the prohibition against persons with insulin-treated diabetes mellitus (ITDM) operating...://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . FOR FURTHER INFORMATION CONTACT: Elaine M. Papp, Chief...

  9. 78 FR 1926 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-01-09

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in....gpo.gov/fdsys/pkg/FR-2010-12-29/pdf/2010-32876.pdf . Background On October 31, 2012, FMCSA published a...

  10. 75 FR 50797 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-08-17

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in...://edocket.access.gpo.gov/2008/pdf/E8-785.pdf . Background On June 28, 2010, FMCSA published a Notice of...

  11. 75 FR 27616 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-05-17

    ... vehicle if that person has no established medical history or clinical diagnosis of diabetes mellitus... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in...

  12. 47 CFR 73.4101 - Financial qualifications, TV stations.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Financial qualifications, TV stations. 73.4101 Section 73.4101 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES..., TV stations. See Public Notice, FCC 79-299, dated May 11, 1979. 72 F.C.C. 2d 784; 44 FR 29160, May 18...

  13. Student Mobility, Qualifications and Academic Recognition in the EU

    Science.gov (United States)

    West, Anne; Barham, Eleanor

    2009-01-01

    This paper explores the relationship between student mobility, qualifications and academic recognition within Europe. It provides an outline of supranational legal instruments and policies in relation to academic recognition and student mobility. It then examines some of the difficulties associated with the different concepts underpinning the…

  14. 77 FR 19749 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-04-02

    .... Shaffer Mr. Shaffer, 61, has a prosthetic right eye due to a traumatic injury sustained as a child. The.... Qualifications of Applicants Robert J. Abbas Mr. Abbas, age 62, has had amblyopia in his left eye since birth. The best corrected visual acuity in right eye is 20/20 and in his left eye, 20/100. Following an...

  15. 77 FR 10610 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-02-22

    .... Shaffer, 61, has a prosthetic right eye due to a traumatic injury sustained as a child. The best corrected.... Qualifications of Applicants Robert J. Abbas Mr. Abbas, age 62, has had amblyopia in his left eye since birth. The best corrected visual acuity in right eye is 20/20 and in his left eye, 20/100. Following an...

  16. 14 CFR 125.281 - Pilot-in-command qualifications.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Pilot-in-command qualifications. 125.281... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS CERTIFICATION... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Flight Crewmember...

  17. 14 CFR 125.283 - Second-in-command qualifications.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Second-in-command qualifications. 125.283... (CONTINUED) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS CERTIFICATION... CAPACITY OF 6,000 POUNDS OR MORE; AND RULES GOVERNING PERSONS ON BOARD SUCH AIRCRAFT Flight Crewmember...

  18. 41 CFR 51-4.3 - Maintaining qualification.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Maintaining qualification. 51-4.3 Section 51-4.3 Public Contracts and Property Management Other Provisions Relating to Public...) Furnish commodities or services in strict accordance with Government orders. (2) Comply with the...

  19. Competences as the Core Element of the European Qualifications Framework

    Science.gov (United States)

    Bohlinger, Sandra

    2008-01-01

    The development and implementation of the EQF, as a meta-framework for the promotion of transparency, quality assurance, mobility and mutual recognition of qualifications, has given rise to some difficulties. These are due partly to different definitions of competences, skills and knowledge. Taking the German-speaking countries as an example, the…

  20. 18 CFR 41.12 - Qualifications of accountants.

    Science.gov (United States)

    2010-04-01

    ... accountants. 41.12 Section 41.12 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Regulations § 41.12 Qualifications of accountants. The Commission will not recognize any certified public accountant or public accountant through December 31, 1975, who is not in fact independent. Beginning January...

  1. 18 CFR 158.12 - Qualifications of accountants.

    Science.gov (United States)

    2010-04-01

    ... accountants. 158.12 Section 158.12 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Proposed Remedies § 158.12 Qualifications of accountants. The Commission will recognize only independent certified public accountants, or independent licensed public accountants who were licensed on or before...

  2. Navigating the National Qualifications Framework (NQF): The role of ...

    African Journals Online (AJOL)

    The South African Qualifications Authority (SAQA) recently commissioned a review of the career development field in South Africa. The review was designed to clarify what SAQA's role might be in assisting learners throughout life to navigate their ways through the complex array of education, training and work opportunities ...

  3. The Impact of Teacher Qualification and Subject Major in the ...

    African Journals Online (AJOL)

    The simple correlation and regression statistics at the 0.01 and 0.05 significant levels were utilized for data analysis as well as the statistical inference. Findings indicated a significant positive relationship between students' academic achievement in mathematics and teacher qualification and subject majors. The findings ...

  4. 77 FR 5874 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-02-06

    ... loss of vision in his left eye due to a traumatic injury sustained in 2008. The best corrected visual... violations in a CMV. Gary Vines Mr. Vines, 47, has had complete loss of vision in his left eye due to a... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision...

  5. 77 FR 56261 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-09-12

    ... L. Blakeley II Mr. Blakeley, age 60, has had loss of vision in his left eye due to a traumatic... violations in a CMV. Paul M. Griffey Mr. Griffey, 59, has loss of vision in his left eye due to retinal... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Vision...

  6. Academic Qualification And School Type Differentials In Nigerian ...

    African Journals Online (AJOL)

    Academic Qualification And School Type Differentials In Nigerian Higher Institutions\\' Secretaries Performance In Automated Offices. ... And that state government owned higher institutions should be made to enjoy financial reinforcement from the federal government. IFE PsychologIA Vol. 15 (2) 2007: pp. 164-178 ...

  7. 48 CFR 53.301-330 - Architect-Engineer Qualifications.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Architect-Engineer Qualifications. 53.301-330 Section 53.301-330 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION (CONTINUED) CLAUSES AND FORMS FORMS Illustrations of Forms 53.301-330 Architect-Engineer...

  8. Teacher Qualification Guidelines, Ecological Literacy and Outdoor Education

    Science.gov (United States)

    Martin, Peter

    2008-01-01

    A key signpost to a profession is clarity of disciplinary knowledge. In this paper I describe the content and outcome of a process to refine the qualification guidelines for outdoor education teachers in Victorian, Australia. The guidelines, developed for the Victorian Institute of Teaching, include both practical skills and disciplinary…

  9. 49 CFR 192.227 - Qualification of welders.

    Science.gov (United States)

    2010-10-01

    ... of welders. (a) Except as provided in paragraph (b) of this section, each welder must be qualified in accordance with section 6 of API 1104 (incorporated by reference, see § 192.7) or section IX of the ASME... 49 Transportation 3 2010-10-01 2010-10-01 false Qualification of welders. 192.227 Section 192.227...

  10. 49 CFR 195.222 - Welders: Qualification of welders.

    Science.gov (United States)

    2010-10-01

    ... be qualified in accordance with section 6 of API 1104 (incorporated by reference, see § 195.3) or section IX of the ASME Boiler and Pressure Vessel Code, (incorporated by reference, see § 195.3) except... 49 Transportation 3 2010-10-01 2010-10-01 false Welders: Qualification of welders. 195.222 Section...

  11. 24 CFR 1720.120 - Qualification for appearances.

    Science.gov (United States)

    2010-04-01

    ... HOUSING AND URBAN DEVELOPMENT (INTERSTATE LAND SALES REGISTRATION PROGRAM) FORMAL PROCEDURES AND RULES OF... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Qualification for appearances. 1720.120 Section 1720.120 Housing and Urban Development Regulations Relating to Housing and Urban...

  12. Teacher gender, qualification and experience as predictors of ...

    African Journals Online (AJOL)

    ... attitude towards teaching is 5.1%, which is not statistically significant. Out of all the three independent variables, only teacher qualification accounts for 4.8% of the total variance in science teacher attitude towards teaching, which is statistically significant. International Journal of Emotional Psychology and Sport Ethics Vol.

  13. Decant pump assembly and controls qualification testing - test report

    Energy Technology Data Exchange (ETDEWEB)

    Staehr, T.W., Westinghouse Hanford

    1996-05-02

    This report summarizes the results of the qualification testing of the supernate decant pump and controls system to be used for in-tank sludge washing in aging waste tank AZ-101. The test was successful and all components are qualified for installation and use in the tank.

  14. Labour Market Outcomes of National Qualifications Frameworks in Six Countries

    Science.gov (United States)

    Allais, Stephanie

    2017-01-01

    This article presents the major findings of an international study that attempted to investigate the labour market outcomes of qualifications frameworks in six countries--Belize, France, Ireland, Jamaica, Sri Lanka, and Tunisia, as well as the regional framework in the Caribbean. It finds limited evidence of success, but fairly strong support for…

  15. 47 CFR 54.415 - Consumer qualification for Link Up.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Consumer qualification for Link Up. 54.415 Section 54.415 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) UNIVERSAL SERVICE Universal Service Support for Low-Income Consumers § 54.415 Consumer...

  16. Assessment Rocks? The Assessment of Group Composing for Qualification

    Science.gov (United States)

    Thorpe, Vicki

    2012-01-01

    Ensembles such as rock and pop bands are places of exciting creativity and intense, enjoyable music making for young people. A recent review of New Zealand's secondary school qualification, the National Certificates of Educational Achievement (NCEA), has resulted in a new composition assessment of individuals' achievement in groups. An analysis of…

  17. National Vocational Qualifications in a Business Studies Degree.

    Science.gov (United States)

    Morgan, Arthur

    1997-01-01

    Job descriptions of eight British business students employed in various settings were compared to National Vocational Qualifications (NVQs) management standards. Five students were able to complete work for assessment; three were recommended for NVQs. The project demonstrated the utility of NVQs in the business studies degree program. (SK)

  18. 78 FR 65754 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2013-11-01

    ... Federal Motor Carrier Safety Administration Qualification of Drivers; Exemption Applications; Diabetes... persons with insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in... August 19, 2013, FMCSA published a notice of receipt of Federal diabetes exemption applications from 23...

  19. Teacher qualification and teaching techniques in nursery schools in ...

    African Journals Online (AJOL)

    The scarcity of qualified teachers in Early Childhood Education in Rwanda in general, and in Kicukiro District in particular, raised interest and curiosity to conduct this study. Its main purpose was to examine the relationship between the qualification of teachers and their teaching techniques in preschools in Kicukiro District.

  20. 7 CFR 900.351 - Applications for qualification.

    Science.gov (United States)

    2010-01-01

    ... SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE GENERAL REGULATIONS Procedure for Determining the Qualification of Cooperative Milk Marketing Associations § 900.351... authorization to collect payment from handlers for members' milk; and is rendering specified marketing services...

  1. Quality assurrance, benchmarking, assessment and mutual international recognition of qualifications

    NARCIS (Netherlands)

    Hobson, R.; Rolland, S.; Rotgans, J.; Schoonheim-Klein, M.; Best, H.; Chomyszyn-Gajewska, M.; Dymock, D.; Essop, R.; Hupp, J.; Kundzina, R.; Love, R.; Memon, R.A.; Moola, M.; Neumann, L.; Ozden, N.; Roth, K.; Samwel, P.; Villavicencio, J.; Wright, P.; Harzer, W.

    2008-01-01

    The aim of this report is to provide guidance to assist in the international convergence of quality assurance, benchmarking and assessment systems to improve dental education. Proposals are developed for mutual recognition of qualifications, to aid international movement and exchange of staff and

  2. 13 CFR 120.841 - Qualifications for the ALP.

    Science.gov (United States)

    2010-01-01

    ... impacts performance measures, and other performance related measurements and information (such as... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Qualifications for the ALP. 120.841 Section 120.841 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS...

  3. Towards a European Qualifications Framework: Some Cautionary Observations

    Science.gov (United States)

    Young, Michael

    2008-01-01

    Purpose: This paper aims to provide a critical analysis of the European Commissions and the member states attempts to introduce a European Qualifications Framework and national frameworks respectively. Design/methodology/approach: The paper is based on a review of policies and substantive desk research in countries that have applied a…

  4. International Harmonization of Training and Qualification in the Manufacturing Industry

    Science.gov (United States)

    Quintino, L.; Fernandes, I.; Miranda, R. M.

    2011-01-01

    Purpose: The aim of this paper is to propose a model for international harmonization of the training and qualification of human resources for industrial professions. The outcome is a system based on training guidelines and a quality assurance methodology that is now in use in 42 countries around the world. Design/methodology/approach: The paper…

  5. Preschool Teacher Candidates' Research Qualifications and Anxiety Level towards Research

    Science.gov (United States)

    Konokman, Gamze Yavuz; Yelken, Tugba; Yokus, Gürol

    2015-01-01

    Problem Statement: Acquisition of research qualifications are one of the most demanded learning outcomes of education faculties. There is great emphasis on building a research identity by developing the skills of students in the department of education faculties. However, very few surveys analyze the current situation of university students in the…

  6. 77 FR 59450 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2012-09-27

    ... [FMCSA Docket No. FMCSA-2012-0164] Qualification of Drivers; Exemption Applications; Diabetes Mellitus... insulin-treated diabetes mellitus (ITDM) from operating commercial motor vehicles (CMVs) in interstate... complying with the current regulation 49 CFR 391.41(b)(3). Diabetes Mellitus and Driving Experience of the...

  7. 75 FR 69734 - Qualification of Drivers; Exemption Applications; Diabetes Mellitus

    Science.gov (United States)

    2010-11-15

    ... [Docket No. FMCSA-2010-0355] Qualification of Drivers; Exemption Applications; Diabetes Mellitus AGENCY... from the diabetes mellitus standard; request for comments. SUMMARY: FMCSA announces receipt of... diabetes mellitus (ITDM) operating commercial motor vehicles (CMVs) in interstate commerce. If granted, the...

  8. 42 CFR 493.1469 - Standard: Cytology general supervisor qualifications.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Standard: Cytology general supervisor... Nonwaived Testing Laboratories Performing High Complexity Testing § 493.1469 Standard: Cytology general supervisor qualifications. The cytology general supervisor must be qualified to supervise cytology services...

  9. 77 FR 27852 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-05-11

    ... submitted on behalf of an association, business, labor union, etc.). You may review DOT's Privacy Act.... Qualifications of Applicants Charles S. Amyx, Jr. Mr. Amyx, age 46, had an enucleation of his right eye due to a... functioniong right eye.'' Mr. Amyx reported that he has driven tractor-trailer combinations for 24 years...

  10. 29 CFR 452.35 - Qualifications for candidacy.

    Science.gov (United States)

    2010-07-01

    ... purpose of the Act is to ensure the right of members to participate fully in governing their union and to... 29 Labor 2 2010-07-01 2010-07-01 false Qualifications for candidacy. 452.35 Section 452.35 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT...

  11. 78 FR 10251 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-02-13

    ..., business, labor union, etc.). You may review DOT's Privacy Act Statement for the Federal Docket Management.... Qualifications of Applicants Michael L. Bergman Mr. Bergman, age 56, has a prosthetic right eye due to a... Gonzalez Mr. Gonzalez, 52, has had amblyopia in his left eye since birth. The visual acuity in his right...

  12. 77 FR 27847 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2012-05-11

    ... behalf of an association, business, labor union, etc.). You may review DOT's Privacy Act Statement for.... Qualifications of Applicants Joseph A. Ellis Mr. Ellis, age 51, has loss of vision in his right eye due to a traumatic injury sustained at age 14. The best corrected visual acuity in his right eye is 20/60, and in his...

  13. 78 FR 14405 - Qualification of Drivers; Exemption Applications; Vision

    Science.gov (United States)

    2013-03-05

    ..., business, labor union, etc.). You may review DOT's Privacy Act Statement for the Federal Docket Management.... Qualifications of Applicants David Doub Mr. Doub, 68, has had a retinal detachment in his right eye since 2009. The visual acuity in his right eye is 20/400, and in his left eye, 20/20. Following an examination in...

  14. Using the Degree Qualifications Profile to Foster Meaningful Change

    Science.gov (United States)

    Jankowski, Natasha A.; Giffin, Laura

    2016-01-01

    Examples from the field indicates that effectively using the Degree Qualifications Profile (DQP) can benefit both students and institutions (Jankowski & Giffin, 2016). But what does "effective use" entail and how does it unfold? That is, what is the nature of the process that makes it possible for institutions to use the DQP to…

  15. AGR-3/4 Final Data Qualification Report for ATR Cycles 151A through 155B-1

    Energy Technology Data Exchange (ETDEWEB)

    Pham, Binh T. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-03-01

    Analysis System (NDMAS). The AGR 3/4 data streams addressed in this report include thermocouple (TC) temperatures, sweep gas data (flow rates, pressure, and moisture content), and Fission Product Monitoring System (FPMS) data (release rates, release to birth rate ratios [R/Bs], and particle failure counts) for each of the twelve capsules in the AGR 3/4 experiment. During Outage Cycle 155A, fourteen flow meters were installed downstream from fourteen FPMS monitors to measure flows from the monitors; qualification status of these data are also included in the report. The final data qualification status for these data streams is determined by a Data Review Committee (DRC) composed of AGR technical leads, Sitewide Quality Assurance (QA), and NDMAS analysts. For ATR Cycles 151A through 154B, the DRC convened on February 12, 2014, reviewed the data acquisition process, and considered whether the data met the requirements for data collection as specified in QA approved INL ART TDO data collection plans. The DRC also examined the results of NDMAS data testing and statistical analyses, and confirmed the qualification status of the data as given in this report. The qualification status of AGR-3/4 irradiation data during the first six cycles were previously reported in INL/EXT-14-31186 document. This report presents data qualification status for the entire AGR-3/4 irradiation.

  16. The State of the Otolaryngology Match: A Review of Applicant Trends, "Impossible" Qualifications, and Implications.

    Science.gov (United States)

    Bowe, Sarah N; Schmalbach, Cecelia E; Laury, Adrienne M

    2017-06-01

    Objective This State of the Art Review aims (1) to define recent qualifications of otolaryngology resident applicants by focusing on United States Medical Licensing Examination (USMLE) scores, Alpha Omega Alpha (AOA) status, and research/publications and (2) to summarize the current literature regarding the relationship between these measures and performance in residency. Data Sources Electronic Residency Application Service, National Residency Matching Program, PubMed, Ovid, and GoogleScholar. Review Methods Electronic Residency Application Service and National Residency Matching Program data were analyzed to evaluate trends in applicant numbers and qualifications. Additionally, a literature search was performed with the aforementioned databases to identify relevant articles published in the past 5 years that examined USMLE Step 1 scores, AOA status, and research/publications. Conclusions Compared with other highly competitive fields over the past 3 years, the only specialty with decreasing applicant numbers is otolaryngology, with the rest remaining relatively stable or slightly increased. Additionally, USMLE Step 1 scores, AOA status, and research/publications do not reliably correlate with performance in residency. Implications for Practice The consistent decline in applications for otolaryngology residency is concerning and reflects a need for change in the current stereotype of the "ideal" otolaryngology applicant. This includes consideration of additional selection measures focusing on noncognitive and holistic qualities. Furthermore, otolaryngology faculty should counsel medical students that applying in otolaryngology is not "impossible" but rather a feasible and worthwhile endeavor.

  17. Effluent Management Facility Evaporator Bottom-Waste Streams Formulation and Waste Form Qualification Testing

    Energy Technology Data Exchange (ETDEWEB)

    Saslow, Sarah A.; Um, Wooyong; Russell, Renee L.

    2017-08-02

    This report describes the results from grout formulation and cementitious waste form qualification testing performed by Pacific Northwest National Laboratory (PNNL) for Washington River Protection Solutions, LLC (WRPS). These results are part of a screening test that investigates three grout formulations proposed for wide-range treatment of different waste stream compositions expected for the Hanford Effluent Management Facility (EMF) evaporator bottom waste. This work supports the technical development need for alternative disposition paths for the EMF evaporator bottom wastes and future direct feed low-activity waste (DFLAW) operations at the Hanford Site. High-priority activities included simulant production, grout formulation, and cementitious waste form qualification testing. The work contained within this report relates to waste form development and testing, and does not directly support the 2017 Integrated Disposal Facility (IDF) performance assessment (PA). However, this work contains valuable information for use in PA maintenance past FY 2017 and future waste form development efforts. The provided results and data should be used by (1) cementitious waste form scientists to further the understanding of cementitious leach behavior of contaminants of concern (COCs), (2) decision makers interested in off-site waste form disposal, and (3) the U.S. Department of Energy, their Hanford Site contractors and stakeholders as they assess the IDF PA program at the Hanford Site. The results reported help fill existing data gaps, support final selection of a cementitious waste form for the EMF evaporator bottom waste, and improve the technical defensibility of long-term waste form risk estimates.

  18. Qualification and calibration tests of detector modules for the CMS Pixel Phase 1 upgrade

    Science.gov (United States)

    Zhu, D.; Backhaus, M.; Berger, P.; Meinhard, M.; Starodumov, A.; Tavolaro, V.

    2018-01-01

    In high energy particle physics, accelerator- and detector-upgrades always go hand in hand. The instantaneous luminosity of the Large Hadron Collider will increase to up to L = 2×1034cm‑2s‑1 during Run 2 until 2023. In order to cope with such luminosities, the pixel detector of the CMS experiment has been replaced early 2017. The so-called CMS Pixel phase 1 upgrade detector consists of 1184 modules with new design. An important production step is the module qualification and calibration, ensuring their proper functionality within the detector. This paper summarizes the qualification and calibration tests and results of modules used in the innermost two detector layers with focus on methods using module-internal calibration signals. Extended characterizations on pixel level such as electronic noise and bump bond connectivity, optimization of operational parameters, sensor quality and thermal stress resistance were performed using a customized setup with controlled environment. It could be shown that the selected modules have on average 0.55‰ ± 0.01‰ defective pixels and that all performance parameters stay within their specifications.

  19. PDSS/IMC requirements and functional specifications

    Science.gov (United States)

    1983-01-01

    The system (software and hardware) requirements for the Payload Development Support System (PDSS)/Image Motion Compensator (IMC) are provided. The PDSS/IMC system provides the capability for performing Image Motion Compensator Electronics (IMCE) flight software test, checkout, and verification and provides the capability for monitoring the IMC flight computer system during qualification testing for fault detection and fault isolation.

  20. 42 CFR 484.4 - Personnel qualifications.

    Science.gov (United States)

    2010-10-01

    ... (b) Meets the educational requirements for certification and is in the process of accumulating the... baccalaureate degree in social work, psychology, sociology, or other field related to social work, and has had... Association. (b) The educational requirements for certification and is in the process of accumulating the...

  1. Selection of magister learners in nursing science at the Rand Afrikaans University

    Directory of Open Access Journals (Sweden)

    A Botes

    2001-09-01

    Full Text Available Selection of learners implies that candidates are assessed according to criteria with the purpose of selecting the most suitable learners for the course. A magister qualification is on level 8A of the National Qualifications Framework (NQF. The purpose of a magister qualification in Nursing is the development of advanced research, clinical, professional, managerial, educational, leadership and consultative abilities (knowledge, skills, values and attitudes for the promotion of individual, family, group and community health. From the above introduction it becomes clear that there is a high expectations of a person with a magister qualification. Such a person should be a specialist, scientist, leader and role model in the profession. A magister programme is human-power intensive as well as capital intensive for both the learner and higher education institutions. It is therefore important to select learners with the ability to achieve the outcomes of the programme. Limited research has been conducted on the selection of post graduate learners.

  2. Qualification of Reillex{trademark} HPQ anion exchange resin for use in SRS processes

    Energy Technology Data Exchange (ETDEWEB)

    Crooks, W.J. III

    2000-05-18

    The Phase 2 portion of the HB-Line facility was built in the early 1980's to process plutonium and neptunium from nitric acid solutions into oxide suitable for storage in a vault. Although the other portions of HB-Line were started up in the mid 1980's and have operated since that time, the anion exchange and precipitation processes in Phase 2 were never started up. As part of the material stabilization efforts, Phase 2 is currently being started up. A new anion exchange resin is needed because the resins that were proposed for use 10 years ago are limited by performance characteristics, disposal requirements, or are no longer commercially available. SRTC is responsible for qualifying all resins prior to their use in Nuclear Materials Stabilization and Storage (NMSS) processes. Qualification consists of both process suitability and thermal stability with nitric acid. This report describes the thermal stability qualification of Reillex{trademark} HPQ, the new resin proposed for processing plutonium and neptunium in the HB Line facility.

  3. Examination of a Junction-Box Adhesion Test for Use in Photovoltaic Module Qualification (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Miller, D. C.; Wohlgemuth, J. H.

    2012-08-01

    Engineering robust adhesion of the junction-box (j-box) is a hurdle typically encountered by photovoltaic (PV) module manufacturers during product development. There are historical incidences of adverse effects (e.g., fires) caused when the j-box/adhesive/module system has failed in the field. The addition of a weight to the j-box during the 'damp heat' IEC qualification test is proposed to verify the basic robustness of its adhesion system. The details of the proposed test will be described, in addition to the preliminary results obtained using representative materials and components. The described discovery experiments examine moisture-cured silicone, foam tape, and hot-melt adhesives used in conjunction with PET or glass module 'substrates.' To be able to interpret the results, a set of material-level characterizations was performed, including thermogravimetric analysis, differential scanning calorimetry, and dynamic mechanical analysis. PV j-boxes were adhered to a substrate, loaded with a prescribed weight, and then placed inside an environmental chamber (at 85C, 85% relative humidity). Some systems did not remain attached through the discovery experiments. Observed failure modes include delamination (at the j-box/adhesive or adhesive/substrate interface) and phase change/creep. The results are discussed in the context of the application requirements, in addition to the plan for the formal experiment supporting the proposed modification to the qualification test.

  4. Internal qualification and credentialing of radiation oncology physicists to perform patient special procedures

    Directory of Open Access Journals (Sweden)

    Michael D Mills

    2014-01-01

    Full Text Available In the arena of radiation oncology special procedures, medical physicists are often the focus professionals for implementation and administration of advanced and complex technologies. One of the most vexing and challenging aspects of managing complexity concerns the ongoing internal qualification and credentialing of radiation oncology physicists to perform patient special procedures. To demonstrate ongoing qualification, a physicist must a document initial training and successful completion of competencies to implement and perform this procedure, b demonstrate familiarity with all aspects of the commissioning and quality assurance process, c demonstrate continuing education respecting this procedure, d demonstrate the peer-reviewed completion of a minimum number of patient special procedures during a specified time span, and e demonstrate satisfactory overall progress toward maintenance of specialty board certification. In many respects, this information complement is similar to that required by an accredited residency program in therapy physics. In this investigation, we report on the design of a management tool to qualify staff radiation oncology physicists to deliver patient procedures.

  5. Examination of a Junction-Box Adhesion Test for Use in Photovoltaic Module Qualification: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Miller, D. C.; Wohlgemuth, J. H.

    2012-08-01

    Engineering robust adhesion of the junction-box (j-box) is a hurdle typically encountered by photovoltaic (PV) module manufacturers during product development. There are historical incidences of adverse effects (e.g., fires) caused when the j-box/adhesive/module system has failed in the field. The addition of a weight to the j-box during the 'damp heat' IEC qualification test is proposed to verify the basic robustness of its adhesion system. The details of the proposed test will be described, in addition to the preliminary results obtained using representative materials and components. The described discovery experiments examine moisture-cured silicone, foam tape, and hot-melt adhesives used in conjunction with PET or glass module 'substrates.' To be able to interpret the results, a set of material-level characterizations was performed, including thermogravimetric analysis, differential scanning calorimetry, and dynamic mechanical analysis. PV j-boxes were adhered to a substrate, loaded with a prescribed weight, and then placed inside an environmental chamber (at 85C, 85% relative humidity). Some systems did not remain attached through the discovery experiments. Observed failure modes include delamination (at the j-box/adhesive or adhesive/substrate interface) and phase change/creep. The results are discussed in the context of the application requirements, in addition to the plan for the formal experiment supporting the proposed modification to the qualification test.

  6. 34 CFR 300.156 - Personnel qualifications.

    Science.gov (United States)

    2010-07-01

    ... in their discipline or profession— (i) Meet the requirements of paragraph (b)(1) of this section; and... with the SEA as provided for under this part. (Approved by the Office of Management and Budget under...

  7. Prevalence of GMC performance assessments in the United Kingdom: a retrospective cohort analysis by country of medical qualification.

    Science.gov (United States)

    Mehdizadeh, L; Potts, H W W; Sturrock, A; Dacre, J

    2017-04-04

    The demographics of doctors working in the UK are changing. The United Kingdom (UK) has voted to leave the European Union (EU) and there is heightened political discourse around the world about the impact of migration on healthcare services. Previous work suggests that foreign trained doctors perform worse than UK graduates in postgraduate medical examinations. We analysed the prevalence by country of primary medical qualification of doctors who were required to take an assessment by the General Medical Council (GMC) because of performance concerns. This was a retrospective cohort analysis of data routinely collected by the GMC. We compared doctors who had a GMC performance assessment between 1996 and 2013 with the medical register in the same period. The outcome measures were numbers experiencing performance assessments by country or region of medical qualification. The rate of performance assessment varied significantly by place of medical qualification and by year; χ 2(17) = 188, p environment the UK should adopt once it leaves the EU. Patients should be reassured that the vast majority of all doctors working in the UK are competent.

  8. Sludge Washing And Demonstration Of The DWPF Flowsheet In The SRNL Shielded Cells For Sludge Batch 8 Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Pareizs, J. M.; Crawford, C. L.

    2013-04-26

    The current Waste Solidification Engineering (WSE) practice is to prepare sludge batches in Tank 51 by transferring sludge from other tanks to Tank 51. Tank 51 sludge is washed and transferred to Tank 40, the current Defense Waste Processing Facility (DWPF) feed tank. Prior to transfer of Tank 51 to Tank 40, the Savannah River National Laboratory (SRNL) typically simulates the Tank Farm and DWPF processes using a Tank 51 sample (referred to as the qualification sample). WSE requested the SRNL to perform characterization on a Sludge Batch 8 (SB8) sample and demonstrate the DWPF flowsheet in the SRNL shielded cells for SB8 as the final qualification process required prior to SB8 transfer from Tank 51 to Tank 40. A 3-L sample from Tank 51 (the SB8 qualification sample; Tank Farm sample HTF-51-12-80) was received by SRNL on September 20, 2012. The as-received sample was characterized prior to being washed. The washed material was further characterized and used as the material for the DWPF process simulation including a Sludge Receipt and Adjustment Tank (SRAT) cycle, a Slurry Mix Evaporator (SME) cycle, and glass fabrication and chemical durability measurements.

  9. Functional diversification of hsp40: distinct j-protein functional requirements for two prions allow for chaperone-dependent prion selection.

    Science.gov (United States)

    Harris, Julia M; Nguyen, Phil P; Patel, Milan J; Sporn, Zachary A; Hines, Justin K

    2014-07-01

    Yeast prions are heritable amyloid aggregates of functional yeast proteins; their propagation to subsequent cell generations is dependent upon fragmentation of prion protein aggregates by molecular chaperone proteins. Mounting evidence indicates the J-protein Sis1 may act as an amyloid specificity factor, recognizing prion and other amyloid aggregates and enabling Ssa and Hsp104 to act in prion fragmentation. Chaperone interactions with prions, however, can be affected by variations in amyloid-core structure resulting in distinct prion variants or 'strains'. Our genetic analysis revealed that Sis1 domain requirements by distinct variants of [PSI+] are strongly dependent upon overall variant stability. Notably, multiple strong [PSI+] variants can be maintained by a minimal construct of Sis1 consisting of only the J-domain and glycine/phenylalanine-rich (G/F) region that was previously shown to be sufficient for cell viability and [RNQ+] prion propagation. In contrast, weak [PSI+] variants are lost under the same conditions but maintained by the expression of an Sis1 construct that lacks only the G/F region and cannot support [RNQ+] propagation, revealing mutually exclusive requirements for Sis1 function between these two prions. Prion loss is not due to [PSI+]-dependent toxicity or dependent upon a particular yeast genetic background. These observations necessitate that Sis1 must have at least two distinct functional roles that individual prions differentially require for propagation and which are localized to the glycine-rich domains of the Sis1. Based on these distinctions, Sis1 plasmid-shuffling in a [PSI+]/[RNQ+] strain permitted J-protein-dependent prion selection for either prion. We also found that, despite an initial report to the contrary, the human homolog of Sis1, Hdj1, is capable of [PSI+] prion propagation in place of Sis1. This conservation of function is also prion-variant dependent, indicating that only one of the two Sis1-prion functions may have

  10. AGC-4 Experiment Irradiation Monitoring Data Qualification Interim Report

    Energy Technology Data Exchange (ETDEWEB)

    Hull, Laurence Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    The Graphite Technology Development Program is running a series of six experiments to quantify the effects of irradiation on nuclear grade graphite. The fourth experiment, Advanced Graphite Creep 4 (AGC 4), began with Advanced Test Reactor (ATR) cycle 157D on May 30, 2015, and has been irradiated for two cycles. The capsule was removed from the reactor after ATR cycle 158A, which ended on January 2, 2016, due to interference with another experiment. Irradiation will resume when the interfering experiment is removed from the reactor. This report documents qualification of AGC 4 experiment irradiation monitoring data for use by the Advanced Reactor Technologies (ART) Technology Development Office (TDO) Program for research and development activities required to design and license the first HTR nuclear plant. Qualified data meet the requirements for use as described in the experiment planning and quality assurance documents. Failed data do not meet the requirements and provide no useable information. Trend data may not meet all requirements, but still provide some useable information. Use of Trend data requires assessment of how any deficiencies affect a particular use of the data. All thermocouples (TCs) have functioned throughout the AGC-4 experiment. All temperature data are Qualified for use by the ART TDO Program. Argon, helium, and total gas flow data were within expected ranges and are Qualified for use by the ART TDO Program. Discharge gas line moisture values were consistently low during cycle 157D. At the start of cycle 158A, gas moisture briefly spiked to over 600 ppmv and then declined throughout the cycle. Moisture values are within the measurement range of the instrument and are Qualified for use by the ART TDO Program. Graphite creep specimens were subjected to one of three loads, 393, 491, or 589 lbf. For a brief period during cycle 157D between 12:19 on June 2, 2015 and 08:23 on June 11, 2015 the load cells were wired incorrectly resulting in missing

  11. Regulations on measures to promote the qualification of women in universities, colleges, and technical schools, 31 August 1988.

    Science.gov (United States)

    1988-01-01

    These Regulations of the German Democratic Republic, introduced on 1 October 1988, are intended to make it easier for certain categories of women--particularly those with heavy family responsibilities--to study at universities and technical colleges in the German Democratic Republic. The regulations apply to women who have either several children under age 16; a severely handicapped child under age 18; or a family member requiring continual care, supervision, or support. To benefit from the new scheme, women must be selected to sign a "training agreement" by an enterprise, which must have formal plans for promoting its female workforce. Once courses are completed, trainees must be integrated into jobs corresponding to their new skills. The new regulations make it easier to follow correspondence courses by allowing up to 100 days of paid time off each year for study and examination purposes. In following a full-time course, women will receive an allowance equalling 80% of the difference between a basic student allowance and her actual or average earnings prior to enrolling in the course. This will be paid by the employing enterprise. In addition to time off from work, enterprises must provide a support network which includes welfare services, reduced workload, use of the enterprise's training equipment and facilities, and the provision of work assignments linked to training. Steps must be taken to assist women to acquire the qualifications for access to executive and managerial functions. At the core of the new scheme is a whole new range of "specially tailored" correspondence and evening courses which have been introduced into universities and technical colleges. With an average course duration of four and half to five years, course participants will all be nominated by their employing enterprise. The scheme as a whole will be progressively extended to cover all branches of engineering, economic, and agrarian sciences, with special emphasis on information

  12. PICA Forebody Heatshield Qualification for the Stardust Discovery Class Mission

    Science.gov (United States)

    Tran, Huy K.; Johnson, Christine E.; Hsu, Ming-Ta; Smith, Marnell; Dill, Harry; Rasky, Daniel J. (Technical Monitor)

    1996-01-01

    This paper presents the qualification of the light weight Phenolic Impregnated Carbon Ablators (PICA) as the forebody heatshield for the Stardust Discovery Class Mission. The Stardust spacecraft will be launched in early 1999 and fly by Comet Wild-2 to collect cometary and interstellar dust and return them back to earth in the Sample Return Capsule (SRC). This earth re-entry will be the fastest to date, at 12.6 km/s, and therefore requires a heatshield that can withstand very high heating rates and stagnation pressures, as well as provide the necessary insulation to the vehicle structure. The PICA material was developed as part of the Lightweight Ceramic Ablators program at NASA Ames Research Center, and was baselined as the forebody heatshield because of its low density and superior ablation and thermal performance at severe aerothermodynamic conditions. Under a Small Business Innovative Research (SBIR) program with NASA Ames, Fiber Materials, Inc. developed a process to manufacture a single-piece PICA heatshield for the forebody of the SRC, along with witness material for the fabrication of the test models. The test models were fabricated and instrumented by the staff of Lockheed Martin Astronautics in Denver, Colorado. Full body preliminary aerothermal CFD calculations were performed at NASA Ames to determine the heating and stagnation pressure conditions. The Heat shield sizing was also performed at NASA Ames by using a new material response code that accounts for the highly porous characteristics of the PICA material. The ablation and thermal performance of PICA was qualified in the NASA Ames Interaction Heating Arc Jet Facility. A total of 24 models and four test conditions were used to qualify PICA at the predicted peak heat flux, heat load, shear, and stagnation pressure conditions. Surface and in-depth temperatures were measured using optical pyrometers and thermocouples. Surface recession was measured by using a template and a height gage. Several models

  13. OF INDICES of CENTRAL COMPARATIVE ANALYSIS HEMODYNAMICS IN SPORTSMEN-JUDOISTS of HIGH QUALIFICATION DEPENDING ON AGE, QUALIFICATION AND LENGTH OF TRAINING

    Directory of Open Access Journals (Sweden)

    І. М. Oleksenko

    2012-11-01

    Full Text Available Research and analysis of indices of central hemodynamics are conducted in 101 sportsmen of high qualification, members of combined team of Ukraine on judo. The sizes of laboratory indices of integral reovazografy are set that are peculiar for the sportsmen-judoists divided for age, sports qualification and experience of training in judo

  14. Rivet Qualification of Aluminum Alloy 7050.

    Science.gov (United States)

    1976-10-01

    see Table 1). They were Immediately stress relieved by heating at 650OF overnight. Slices were cut 10 in. from the head end (top) of each ingot to...order to Keeo the hammer centered on the rivet during the driving operation. Selected rivets of all three diameters were sectioned for defects and hole...7050-T7X riveted joints and most of the 2024-T31 riveted joints initiated in the region of the knife edge produced by the countersink. Most such

  15. From qualification design to training design using ECVET principles

    Energy Technology Data Exchange (ETDEWEB)

    Ceclan, Mihail; Wastin, Franck [European Commission Joint Research Centre, Petten (Netherlands). Directorate Nuclear Safety and Security

    2017-05-15

    The Joint Research Centre of European Commission was designated in 2009 as Operating agent of European Human Resources Observatory - in Nuclear (EHRO@N). EHRO@N identified the nuclear sector's major challenges: to fill@in the 30 % gap between HR demand and supply in decommissioning and to adapt nuclear E and T system to comply more to the labour market demands. The process of nuclear training system adaptation to the labour market needs is based on the design of the flexible qualifications (unit based qualifications) using European Credit system for Vocational Education and Training (ECVET) principles. The process of ECVET implementation in the nuclear energy sector is ongoing since 2011 and is based on the strategy and road map developed by EHRO-N. The current paper presents the latest developments on the designing of training programs based on exit outcomes.

  16. Qualification Strategies in ICT For Europe and Romania

    Directory of Open Access Journals (Sweden)

    Viorel ARITON

    2005-10-01

    Full Text Available In the international comparison significant differences regarding the future demand come into view. In Romania and Portugal, where theICT qualification is dominated by universities degrees, the companies correspondingly see the biggest demand on qualification level 5M (masters’degree. For Portugal this is the only group where companies see a significantly higher demand in the near future. For the Czech Republic andGermany only one fifth of the companies say there will be a higher demand on university based level 5M and in the Netherlands, it is even less, withonly 10% of the companies. In these three countries - and particularly in the Czech Republic - almost half of the companies foresee a higher demandon level 5B.

  17. Model characteristics of the structure physical training fighters qualifications

    Directory of Open Access Journals (Sweden)

    Pryimakov O.O.

    2013-06-01

    Full Text Available Studied the structure of the relationship of physical fitness level fighters with physical disabilities and special performance. It is studied 147 athletes Ukraine qualifications in Greco-Roman and freestyle wrestling, judo. Applied the methods of anthropometry kaliperometrii, teacher testing, testing of a special performance. It is shown that the qualification defines the relationship and the relationship of morphometric and speed-power performance, the level of special performance athletes. With the advanced training of fighters increased level of speed, force readiness, increase the size Spigot neck, hips, chest, shoulders, reduced the percentage of fat component, increases muscular component, the index increased muscle development. Morphometric parameters with the most skilled fighters and cross-linked Spigot size of the body of the speed and power - explosive power, strength and speed-strength endurance, speed.

  18. Structure of a glycomimetic ligand in the carbohydrate recognition domain of C-type lectin DC-SIGN. Structural requirements for selectivity and ligand design.

    Science.gov (United States)

    Thépaut, Michel; Guzzi, Cinzia; Sutkeviciute, Ieva; Sattin, Sara; Ribeiro-Viana, Renato; Varga, Norbert; Chabrol, Eric; Rojo, Javier; Bernardi, Anna; Angulo, Jesus; Nieto, Pedro M; Fieschi, Franck

    2013-02-20

    In genital mucosa, different fates are described for HIV according to the subtype of dendritic cells (DCs) involved in its recognition. This notably depends on the C-type lectin receptor, langerin or DC-SIGN, involved in gp120 interaction. Langerin blocks HIV transmission by its internalization in specific organelles of Langerhans cells. On the contrary, DC-SIGN enhances HIV trans-infection of T lymphocytes. Thus, approaches aiming to inhibit DC-SIGN, without blocking langerin, represent attractive anti-HIV strategies. We previously demonstrated that dendrons bearing multiple copies of glycomimetic compounds were able to block DC-SIGN-dependent HIV infection in cervical explant models. Optimization of such ligand requires detailed characterization of its binding mode. In the present work, we determined the first high-resolution structure of a glycomimetic/DC-SIGN complex by X-ray crystallography. This glycomimetic, pseudo-1,2-mannobioside, shares shape and conformational properties with Manα1-2Man, its natural counterpart. However, it uses the binding epitope previously described for Lewis X, a ligand specific for DC-SIGN among the C-type lectin family. Thus, selectivity gain for DC-SIGN versus langerin is observed with pseudo-1,2-mannobioside as shown by surface plasmon resonance analysis. In parallel, ligand binding was also analyzed by TR-NOESY and STD NMR experiments, combined with the CORCEMA-ST protocol. These studies demonstrate that the complex, defined by X-ray crystallography, represents the unique binding mode of this ligand as opposed to the several binding orientations described for the natural ligand. This exclusive binding mode and its selective interaction properties position this glycomimetic as a good lead compound for rational improvement based on a structurally driven approach.

  19. Is the eCura system useful for selecting patients who require radical surgery after noncurative endoscopic submucosal dissection for early gastric cancer? A comparative study.

    Science.gov (United States)

    Hatta, Waku; Gotoda, Takuji; Oyama, Tsuneo; Kawata, Noboru; Takahashi, Akiko; Yoshifuku, Yoshikazu; Hoteya, Shu; Nakagawa, Masahiro; Hirano, Masaaki; Esaki, Mitsuru; Matsuda, Mitsuru; Ohnita, Ken; Yamanouchi, Kohei; Yoshida, Motoyuki; Dohi, Osamu; Takada, Jun; Tanaka, Keiko; Yamada, Shinya; Tsuji, Tsuyotoshi; Ito, Hirotaka; Hayashi, Yoshiaki; Nakamura, Tomohiro; Nakaya, Naoki; Shimosegawa, Tooru

    2017-10-05

    We have established a risk-scoring system, termed the "eCura system," for the risk stratification of lymph node metastasis in patients who have received noncurative endoscopic submucosal dissection (ESD) for early gastric cancer (EGC). We aimed to clarify whether this system contributes to the selection of patients requiring radical surgery after ESD. Between 2000 and 2011, 1,969 patients with noncurative ESD for EGC were included in this multicenter study. Depending on the treatment strategy after ESD, we had patients with no additional treatment (n = 905) and those with radical surgery after ESD (n = 1,064). After the application of the eCura system to these patients, cancer recurrence and cancer-specific mortality in each risk category of the system were compared between the two patient groups. Multivariate Cox analysis revealed that in the high-risk category, cancer recurrence was significantly higher (hazard ratio = 3.13, p = 0.024) and cancer-specific mortality tended to be higher (hazard ratio = 2.66, p = 0.063) in patients with no additional treatment than in those with radical surgery after ESD, whereas no significant differences were observed in the intermediate-risk and low-risk categories. In addition, cancer-specific survival in the low-risk category was high in both patient groups (99.6 and 99.7%). A limitation of this study is that it included a small number of cases with undifferentiated-type EGC (292 cases). The eCura system is a useful aid for selecting the appropriate treatment strategy after noncurative ESD for EGC. However, caution is needed when applying this system to patients with undifferentiated-type EGC.

  20. Next Generation Qualification: Nanometrics T120PH Seismometer Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Merchant, Bion J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Slad, George William [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-10-01

    Sandia National Laboratories has tested and evaluated three seismometers, the Trillium 120PH, manufactured by Nanometrics. These seismometers measure broadband ground velocity using a UVW configuration with feedback control in a mechanically levelled borehole package. The purpose of the seismometer evaluation was to determine a measured sensitivity, response, self- noise, dynamic range, and self-calibration ability. The Nanometrics Trillium 120PH seismometers are being evaluated for the U.S. Air Force as part of their Next Generation Qualification effort.

  1. Mechanical qualification of collagen membranes used in dentistry

    OpenAIRE

    Emanuela Ortolani; Fabrizio Quadrini; Denise Bellisario; Loredana Santo; Antonella Polimeni; Anna Santarsiero

    2015-01-01

    AIM. The aim of this work is the qualification of commercially available collagen membranes in a comparative manner. The natural origin of collagen makes standardization difficult. Nevertheless, through dimensional and mechanical measures it is possible to mechanically qualify collagen membranes, and compare them. METHODS. Three commercially available collagen membranes used in Guided Bone Regeneration (GBR) and in Guided Tissue Regeneration (GTR) techniques, namely Bio-Gide, Collprotect and ...

  2. Do Qualification, Experience and Age Matter for Principals Leadership Styles?

    OpenAIRE

    Muhammad Javed Sawati; Saeed Anwar; Muhammad Iqbal Majoka

    2013-01-01

    The main focus of present study was to find out the prevalent leadership styles of principals in government schools of Khyber Pakhtunkhwa and to find relationship of leadership styles with qualifications, age and experience of the principals. On the basis of analyzed data, four major leadership styles of the principals were identified as Eclectic, Democratic, Autocratic, and Free-rein. However, a small proportion of the principal had no dominant leadership style. This study shows that princip...

  3. Qualifications and ethics education: the views of ICT professionals

    Directory of Open Access Journals (Sweden)

    Yeslam Al-Saggaf

    2017-11-01

    Full Text Available Do information and communications technology (ICT professionals who have ICT qualifications believe that the ethics education they received as part of their ICT degrees helped them recognise ethical problems in the workplace and address them? If they do, are they also influenced by their personal ethics? What else helps them recognise ethical problems in the workplace and address them? And what are their views in relation to the impact of ethics education on professionalism in the ICT workplace? A quantitative survey of 2,315 Australian ICT professionals revealed that participants who reported having various levels of qualifications found ethics education or training, to a small degree, helpful for recognising ethical problems and addressing them; although it is those with Non-ICT qualifications, not those with ICT degrees, who were influenced more by ethics education or training. This suggests that educators need to consider how to better prepare ICT graduates for the workplace challenges and the types of situations they subsequently experience. The survey also found that participants who reported having various levels of qualifications were not influenced by their personal ethics or indeed any other factor making ethics education or training important for developing professionalism. The quantitative survey was followed by qualitative interviews with 43 Australian ICT professionals in six Australian capital cities. These interviews provided further empirical evidence that ethics education is crucial for enabling ICT professionals to recognise ethical problems and resolve them and that educators need to consider how to better prepare ICT graduates for the types of moral dilemmas that they are likely going to face in the workforce.

  4. QUALIFICATION OF THE SECOND ICS-3000 ION CHROMATOGRAPH FOR USE AT THE DEFENSE WASTE PROCESSING FACILITY

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, T.; Mahannah, R.

    2009-12-03

    The ICS-3000 Ion Chromatography (IC) system installed in 221-S M-14 has been qualified for use. The qualification testing was a head to head comparison of the second ICS-3000 with the initial ICS-3000 system that was installed in 221-S M-13. The crosscheck work included standards for instrument calibration and calibration verifications and standards for individual anion analysis, where the standards were traceable back to the National Institute of Standards and Technology (NIST). In addition the crosscheck work included the analysis of simulated Sludge Receipt and Adjustment Tank (SRAT) Receipt, SRAT Product, and Slurry Mix Evaporator (SME) samples, along with radioactive Sludge Batch 5 material from the SRAT and SME tanks. The Defense Waste Processing Facility (DWPF) requires the analysis of specific anions at various stages of its processing of high level waste (HLW). The anions of interest to the DWPF are fluoride, formate, chloride, nitrite, nitrate, sulfate, oxalate, and phosphate. The anion analysis is used to evaluate process chemistry including formic acid/nitric acid additions to establish optimum conditions for mercury stripping, reduction-oxidation (REDOX) chemistry for the melter, nitrite destruction, etc. The DWPF Laboratory (Lab) has recently replaced the Dionex DX-500 ion chromatography (IC) systems that had been used since 1998 by the first of two new ICS-3000 systems. The replacement effort was necessary due to the vendor of the DX-500 systems no longer supporting service contracts after 2008. DWPF purchased three new ICS-3000 systems in September of 2006. The ICS-3000 instruments are (a) designed to be more stable using an eluent generator to make eluent, (b) require virtually no daily chemical handling by the analysts, (c) require less line breaks in the hood, and (d) generally require less maintenance due to the pump configuration only using water versus the current system where the pump uses various hydroxide concentrations. The ICS-3000

  5. Dynamics of Qualifications in Romanian Higher Education, 1968-2010

    Directory of Open Access Journals (Sweden)

    Bogdan Murgescu

    2013-12-01

    Full Text Available The study analyzes the evolution of study programs in the Romanian higher education in two very different institutional settings: during the communist regime, when the state controlled centrally the structure and contents of higher education, and during the post-communist liberalization and expansion of the number of institutions, students and study programs. The analysis investigates the legal foundations of establishing new qualifications, as well as the number and share of the various types of study programs. It allows to identify different phases during the two main historical periods. For example, during the last two decades of the communist rule, the number of study programs and qualifications increased significantly during the 1960s and most of the 1970s, and then contracted the late 1970s to 1989. After the demise of communism, there was a massive expansion in the number of qualifications and study programs, especially in the context of establishing new institutions of higher education and liberalizing to a certain extent the procedures for proposing and implementing new study programs. This expansion was reversed after 2001, and the number of study programs fluctuated considerably up to the enforcement of the National Education Law 1/2011.

  6. Environmental qualification program of electric equipment for Angra 1

    Energy Technology Data Exchange (ETDEWEB)

    Muzitano, Grazielle F.; Justino, Marcelo C.; Silva, Marcos C., E-mail: grazi@eletronuclear.gov.br, E-mail: justino@eletronuclear.gov.br, E-mail: candeia@eletronuclear.gov.br [Eletrobras Termonuclear S.A. (ELETRONUCLEAR), Rio de Janeiro, RJ (Brazil)

    2017-11-01

    This paper describes the development of the environmental qualification program for important electrical equipment (EQPEE) used for safety in Angra 1 Nuclear Power Plant (NPP). The environmental qualification program started in United States of America by the Nuclear Regulatory Commission (NRC) after the Three Mile Island (TMI) Nuclear Power Plant Accident in 1979. In that event, some equipment installed inside the reactor containment of TMI failed due the harsh conditions that occurred after the accident. Because of this fact, the NRC issued the Regulation 50.49 'Environmental qualification of electric equipment important to safety for nuclear power plants'. The Brazilian regulatory commission CNEN also asked Angra 1 to follow this regulation and to implement an EQPEE similar to the programs adopted by American and other NPPs around the world. Due to the importance to maintain the critical equipment operating in normal and abnormal environment conditions, the program aims to assure that this equipment remains qualified to work under the harsh conditions found inside the reactor containment. The aging of these components are also analyzed in this program that is important in the process to extend the operating life of Angra 1 for more 20 years, which is normally referred as Long Term Operation (LTO). (author)

  7. Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.

    Science.gov (United States)

    Li, Weiqiang; Koutmou, Kristin S; Leahy, Daniel J; Li, Min

    2015-07-31

    During systemic RNA interference (RNAi) in Caenorhabditis elegans, RNA spreads across different cells and tissues in a process that requires the systemic RNA interference deficient-1 (sid-1) gene, which encodes an integral membrane protein. SID-1 acts cell-autonomously and is required for cellular import of interfering RNAs. Heterologous expression of SID-1 in Drosophila Schneider 2 cells enables passive uptake of dsRNA and subsequent soaking RNAi. Previous studies have suggested that SID-1 may serve as an RNA channel, but its precise molecular role remains unclear. To test the hypothesis that SID-1 mediates a direct biochemical recognition of RNA molecule and subsequent permeation, we expressed the extracellular domain (ECD) of SID-1 and purified it to near homogeneity. Recombinant purified SID-1 ECD selectively binds dsRNA but not dsDNA in a length-dependent and sequence-independent manner. Genetic missense mutations in SID-1 ECD causal for deficient systemic RNAi resulted in significant reduction in its affinity for dsRNA. Furthermore, full-length proteins with these mutations decrease SID-1-mediated RNA transport efficiency, providing evidence that dsRNA binding to SID-1 ECD is related to RNA transport. To examine the functional similarity of mammalian homologs of SID-1 (SIDT1 and SIDT2), we expressed and purified mouse SIDT1 and SIDT2 ECDs. We show that they bind long dsRNA in vitro, supportive of dsRNA recognition. In summary, our study illustrates the functional importance of SID-1 ECD as a dsRNA binding domain that contributes to RNA transport. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  8. Leaf processing behaviour in Atta leafcutter ants: 90% of leaf cutting takes place inside the nest, and ants select pieces that require less cutting.

    Science.gov (United States)

    Garrett, Ryan W; Carlson, Katherine A; Goggans, Matthew Scott; Nesson, Michael H; Shepard, Christopher A; Schofield, Robert M S

    2016-01-01

    Leafcutter ants cut trimmings from plants, carry them to their underground nests and cut them into smaller pieces before inoculating them with a fungus that serves as a primary food source for the colony. Cutting is energetically costly, so the amount of cutting is important in understanding foraging energetics. Estimates of the cutting density, metres of cutting per square metre of leaf, were made from samples of transported leaf cuttings and of fungal substrate from field colonies of Atta cephalotes and Atta colombica. To investigate cutting inside the nest, we made leaf-processing observations of our laboratory colony, A. cephalotes. We did not observe the commonly reported reduction of the leaf fragments into a pulp, which would greatly increase the energy cost of processing. Video clips of processing behaviours, including behaviours that have not previously been described, are linked. An estimated 2.9 (±0.3) km of cutting with mandibles was required to reduce a square metre of leaf to fungal substrate. Only about 12% (±1%) of this cutting took place outside of the nest. The cutting density and energy cost is lower for leaf material with higher ratios of perimeter to area, so we tested for, and found that the laboratory ants had a preference for leaves that were pre-cut into smaller pieces. Estimates suggest that the energy required to transport and cut up the leaf material is comparable to the metabolic energy available from the fungus grown on the leaves, and so conservation of energy is likely to be a particularly strong selective pressure for leafcutter ants.

  9. Performance demonstration and personnel qualification for ultrasonic examination in service inspection of nuclear power plants; Ultraaeaenitestauksen menetelmaekokeet ja henkiloestoen paetevoeinti ydinvoimalaitosten maeaeraeaikaistarkastuksissa

    Energy Technology Data Exchange (ETDEWEB)

    Sillanpaeae, J.; Saerkiniemi, P.

    1993-02-01

    The ASME Code section XI (App. VII and VIII) requires that ultrasonic examination procedures, equipment and personnel used to detect and size flaws in reactor vessels, piping welds, bolts and studs shall be qualified by performance demonstration. The requirements for the qualifications of ultrasonic testing personnel and also the requirements for specimens, rules for the conduct of performance demonstrations and acceptance criteria have been clarified in this report. The preparation for these requirements is in progress and the situation in different countries e.g. US and England has been discussed. Also the possibilities to fulfill the requirements of Appendix VIII in Finland are dealt with. (29 refs., 7 figs., 5 tabs.).

  10. Status of the beryllium tile bonding qualification activities for the manufacturing of the ITER first wall

    Energy Technology Data Exchange (ETDEWEB)

    Mitteau, Raphaël, E-mail: Raphael.mitteau@iter.org [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Eaton, R.; Perez, G. [ITER Organization, Route de Vinon-sur-Verdon, CS 90 046, 13067 St. Paul Lez Durance Cedex (France); Zacchia, F.; Banetta, S.; Bellin, B. [Fusion for Energy, Josep Pla 2, Torres Diagonal Litoral B3, 08019 Barcelona (Spain); Gervash, A.; Glazunov, D. [Efremov Research Institute, 189631 St. Petersburg (Russian Federation); Chen, J. [Southwestern Institute of Physics, Huangjing Road, Chengdu 610225 (China)

    2015-10-15

    The preparation of the manufacturing of the ITER first wall involves a qualification stage. The qualification aims at demonstrating that manufacturers can deliver the needed reliability and quality for the beryllium to copper bond, before the manufacturing can commence. The qualification is done on semi-prototype, containing relevant features relative to the beryllium armour (about 1/6 of the panel size). The qualification is done by the participating parties, firstly by a manufacturing semi-prototype and then by testing it under heat flux. One semi-prototype is manufactured and is being tested, and further from other manufacturers are still to come. The qualification programme is accompanied by bond defect investigations, which aim at defining defect acceptance criteria. Qualification and defect acceptance programme are supported by thermal and stress analyses, with good agreement regarding the thermal results, and some insights about the governing factors to bond damage.

  11. WTP Waste Feed Qualification: Hydrogen Generation Rate Measurement Apparatus Testing Report

    Energy Technology Data Exchange (ETDEWEB)

    Stone, M. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Newell, J. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Smith, T. E. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Pareizs, J. M. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2016-06-01

    The generation rate of hydrogen gas in the Hanford tank waste will be measured during the qualification of the staged tank waste for processing in the Hanford Tank Waste Treatment and Immobilization Plant. Based on a review of past practices in measurement of the hydrogen generation, an apparatus to perform this measurement has been designed and tested for use during waste feed qualification. The hydrogen generation rate measurement apparatus (HGRMA) described in this document utilized a 100 milliliter sample in a continuously-purged, continuously-stirred vessel, with measurement of hydrogen concentration in the vent gas. The vessel and lid had a combined 220 milliliters of headspace. The vent gas system included a small condenser to prevent excessive evaporative losses from the sample during the test, as well as a demister and filter to prevent particle migration from the sample to the gas chromatography system. The gas chromatograph was an on line automated instrument with a large-volume sample-injection system to allow measurement of very low hydrogen concentrations. This instrument automatically sampled the vent gas from the hydrogen generation rate measurement apparatus every five minutes and performed data regression in real time. The fabrication of the hydrogen generation rate measurement apparatus was in accordance with twenty three (23) design requirements documented in the conceptual design package, as well as seven (7) required developmental activities documented in the task plan associated with this work scope. The HGRMA was initially tested for proof of concept with physical simulants, and a remote demonstration of the system was performed in the Savannah River National Laboratory Shielded Cells Mockup Facility. Final verification testing was performed using non-radioactive simulants of the Hanford tank waste. Three different simulants were tested to bound the expected rheological properties expected during waste feed qualification testing. These

  12. Improving staff selection processes.

    Science.gov (United States)

    Cerinus, Marie; Shannon, Marina

    2014-11-11

    This article, the second in a series of articles on Leading Better Care, describes the actions undertaken in recent years in NHS Lanarkshire to improve selection processes for nursing, midwifery and allied health professional (NMAHP) posts. This is an area of significant interest to these professions, management colleagues and patients given the pivotal importance of NMAHPs to patient care and experience. In recent times the importance of selecting staff not only with the right qualifications but also with the right attributes has been highlighted to ensure patients are well cared for in a safe, effective and compassionate manner. The article focuses on NMAHP selection processes, tracking local, collaborative development work undertaken to date. It presents an overview of some of the work being implemented, highlights a range of important factors, outlines how evaluation is progressing and concludes by recommending further empirical research.

  13. Isotope Brayton ground demonstration testing and flight qualification. Volume 1. Technical program

    Energy Technology Data Exchange (ETDEWEB)

    1974-12-09

    A program is proposed for the ground demonstration, development, and flight qualification of a radioisotope nuclear heated dynamic power system for use on space missions beginning in the 1980's. This type of electrical power system is based upon and combines two aerospace technologies currently under intense development; namely, the MHW isotope heat source and the closed Brayton cycle gas turbine. This power system represents the next generation of reliable, efficient economic electrical power equipment for space, and will be capable of providing 0.5 to 2.0 kW of electric power to a wide variety of spacecraft for earth orbital and interplanetary missions. The immediate design will be based upon the requirements for the Air Force SURVSATCOM mission. The proposal is presented in three volumes plus an Executive Summary. This volume describes the tasks in the technical program.

  14. Qualification and Start of Production of the Ultrasonic Welding Machines for the LHC Interconnections

    CERN Document Server

    Jacquemod, A; Laurent, F; Tock, J P; Vaudaux, L

    2006-01-01

    The Large Hadron Collider (LHC) is presently under installation at CERN, Geneva. The approximately 4000 superconducting corrector magnets required by the machine are powered through copper-stabilized Nb-Ti busbars. To interconnect the magnets along the machine, about 50 000 joints between superconducting cables rated at 600 A have to be performed in-situ during the interconnection activities. An ultrasonic welding technique has been developed and optimised by CERN which led to the development of a dedicated machine which was qualified during the assembly of the STRING II, a 110-m chain of cryomagnets assembled as a prototype of the LHC. The realization of the â series â interconnections together with the procurement of the tooling based on functional specifications have been contracted to a consortium of firms. Qualification tests and acceptance criteria in terms of electrical contact resistance, mechanical resistance, reliability and reproducibility have been defined by CERN. This paper presents the tes...

  15. Qualification, commissioning and in situ monitoring of high heat flux plasma facing components

    Energy Technology Data Exchange (ETDEWEB)

    Escourbiac, F. [Association Euratom-CEA, CEA/DSM/DRFC, CEA/Cadarache, F-13108 Saint Paul Lez Durance (France)], E-mail: frederic.escourbiac@cea.fr; Durocher, A.; Grosman, A.; Cismondi, F.; Courtois, X.; Farjon, J.L.; Schlosser, J. [Association Euratom-CEA, CEA/DSM/DRFC, CEA/Cadarache, F-13108 Saint Paul Lez Durance (France); Merola, M.; Tivey, R. [ITER Team, CEA/Cadarache, F-13108 Saint Paul Lez Durance (France)

    2007-10-15

    Up-to-date development of actively cooled high heat flux (HHF) plasma facing components (PFC) prototypes only allows reduced margins with regards to the ITER thermal requirements. Additionally, perfect quality cannot be ensured along series manufacturing: the presence of flaws which impair the heat transfer capability of the component, in particular at the interface armour/heat sink appears to be statistically unavoidable. In order to ensure a successful series production, a qualification methodology of actively cooled high heat flux plasma facing components is proposed. Secondly, advanced non-destructive techniques developed for HHF PFC commissioning are detailed with definition of acceptance criteria. Finally, innovative diagnostics for in situ monitoring during plasma operations or tokamak shutdowns are investigated in order to prevent immediate damage (safety monitoring); or evaluate component degradation (health monitoring). This work takes into account the relevance to Tore Supra, and is applied to W7X and ITER Divertor HHF PFC.

  16. Site qualification studies of the UCG-SDB at North Knobs, Wyoming

    Energy Technology Data Exchange (ETDEWEB)

    Davis, B.E.; Krajewski, S.A.; Ahner, P.F.; Avasthi, J.M.; Dolde, M.E.; Greenman, C.A.; Miranda, J.E.

    1979-01-01

    The site qualification program for the North Knobs UCG site near Rawlins, Wyoming has been completed. This site will be the location for the field tests of Underground Coal Gasification of Steeply Dipping Beds undertaken by Gulf Research and Development Company for DOE in a cost shared contract. Site characterization included a comprehensive geotechnical analysis along with vegetation, historical, and archeological studies. The G coal seam chosen for these tests is a subbituminous B coal with a true seam thickness of 22 feet and has thin coal benches above and below the main seam. The water table is at 90 feet below the surface. Hydrologic studies have defined the seam as an aquiclude (non-aquifer). The site is deemed restorable to regulatory requirements. Evaluation of this site indicates total acceptability for the three-test program planned by GR and DC.

  17. Design, Qualification and Lessons Learned of the Shutter Calibration Mechanism for EnMAP Mission

    Science.gov (United States)

    Schmidt, Tilo; Muller, Silvio; Bergander, Arvid; Zajac, Kai; Seifart, Klaus

    2015-09-01

    The Shutter Calibration Mechanism (SCM) Assembly is one of three mechanisms which are developed by HTS for the EnMAP instrument in subcontract to OHB System AG Munich. EnMAP is the Environmental Mapping and Analysis Program of the German Space Agency DLR.The binary rotary encoder of the SCM using hall-effect sensors was already presented during ESMATS 2011. This paper summarizes the main functions and design features of the Hardware and focuses on qualification testing which has finished successfully in 2014. Of particular interest is the functional testing of the main drive including the precise hall-effect position sensing system and the test of the fail safe mechanism. In addition to standard test campaign required for QM also a shock emission measurement of the fail safe mechanism activation was conducted.Test conduction and results will be presented with focus on deviations from the expected behaviour, mitigation measures and on lessons learned.

  18. Remote Qualification of HLS and WPS Systems in the LHC Tunnel

    CERN Document Server

    Mainaud Durand, Helene; Marin, Antonio; Rousseau, Michel; Sosin, Mateusz

    2014-01-01

    The position of the inner triplets of the LHC is monitored using Hydrostatic Levelling System (HLS) and Wire Positioning System (WPS). A regulation of these systems is needed to guarantee the sensors’ function. Such a regulation was done in-situ up to now, but the level of residual radiation at the level of the inner triplets will significantly increase with the next steps of LHC operation. Two systems have been designed to perform such a remote qualification: a filling/purging system for the HLS system and a wire displacer system for the WPS. In the paper, the requirements and the solutions proposed are described, with the emphasis on the conceptual design and the results obtained.

  19. Qualification testing of solar photovoltaic powered refrigerator freezers for medical use in remote geographic locations

    Science.gov (United States)

    Kaszeta, W. J.

    1982-01-01

    One of the primary obstacles to the application of vaccination in developing countries is the lack of refrigerated storage. Vaccines exposed to elevated temperatures suffer a permanent loss of potency. Photovoltaic (PV) powered refrigerator/freezer (R/F) units could surmount the problem of refrigeration in remote areas where no reliable commercial power supply is available. The performance measurements of two different models of PV powered R/F units for medical use are presented. Qualification testing consisted of four major procedures: no-load pull down, ice making, steady-state (maintenance), and holdover. Both R/F units met the major World Health Organization (WHO) requirements. However, the testing performed does not provide complete characterization of the two units; such information could be derived only from further extensive test procedures.

  20. 14 CFR 91.531 - Second in command requirements.

    Science.gov (United States)

    2010-01-01

    ...-Powered Multiengine Airplanes and Fractional Ownership Program Aircraft § 91.531 Second in command...-powered multiengine airplane for which two pilots are required under the type certification requirements... the qualifications for second in command prescribed in § 61.55 of this chapter. (d) No person may...

  1. 7 CFR 1724.30 - Borrowers' requirements-engineering services.

    Science.gov (United States)

    2010-01-01

    ... qualification information need not be submitted to RUS unless specifically requested by RUS on a case by case... instruments pertaining to the engineering details required by RUS. (e) Additional requirements related to appropriate seismic safety measures are contained in part 1792, subpart C, of this chapter, Seismic Safety of...

  2. TSBPA's Business Communications Requirement: Has It Made a Difference?

    Science.gov (United States)

    Elrod, Henry; Tiggeman, Theresa; Craven, Annette E.

    2014-01-01

    In 2011, the Texas State Board of Public Accountancy (TSBPA) added a business communications requirement to the qualifications for candidates to sit for the CPA examination by a requirement for two credit hours in business or accounting communications, either through a discrete course, or through integration into certain accounting courses. This…

  3. Space Qualification of Laser Diode Arrays

    Science.gov (United States)

    Troupaki, Elisavet; Kashem, Nasir B.; Allan, Graham R.; Vasilyev, Aleksey; Stephen, Mark

    2005-01-01

    Laser instruments have great potential in enabling a new generation of remote-sensing scientific instruments. NASA s desire to employ laser instruments aboard satellites, imposes stringent reliability requirements under severe conditions. As a result of these requirements, NASA has a research program to understand, quantify and reduce the risk of failure to these instruments when deployed on satellites. Most of NASA s proposed laser missions have base-lined diode-pumped Nd:YAG lasers that generally use quasi-constant wave (QCW), 808 nm Laser Diode Arrays (LDAs). Our group has an on-going test program to measure the performance of these LDAs when operated in conditions replicating launch and orbit. In this paper, we report on the results of tests designed to measure the effect of vibration loads simulating launch into space and the radiation environment encountered on orbit. Our primary objective is to quantify the performance of the LDAs in conditions replicating those of a satellite instrument, determine their limitations and strengths which will enable better and more robust designs. To this end we have developed a systematic testing strategy to quantify the effect of environmental stresses on the optical and electrical properties of the LDA.

  4. Qualification, knowledge and experience of dispensers working at community pharmacies in Pakistan

    Directory of Open Access Journals (Sweden)

    Hussain A

    2011-06-01

    Full Text Available Pharmacies are managed by a variety of dispensers in terms of qualification, knowledge and experience in Pakistan.Objective: The study aimed to document the state of knowledge, experience and qualification of dispensers working at community pharmacies in Pakistan.Methods: A comparative cross sectional study was conducted at a randomly selected sample of 371 pharmacies in the three cities of Pakistan. A structured questionnaire for data collection was developed and finalized by focused group discussions and pilot testing. The data was coded, entered and analyzed by using SPSS Version 16. Kruskal-Wallis and Mann-Whitney tests (p=0.05 were performed to find out differences.Results: Out of total sample of 371 pharmacies, 31.8 % (118 were in Islamabad, 32.4 % (120 in Peshawar and 35.8 % (133 were in Lahore. Fifty percent of the respondents had correct knowledge of range of room temperature at which medicines should be stored. Only 11.1% (41 of the respondents knew about OTC (over the counter drugs which can be sold without prescription while 5.9 % (22 of the respondents were aware of POM (prescription only medicines which can be only sold on a valid prescription. While 87.6% (325, 88.1% (327, 58.7% (318 and 95.7 % (355 of the respondents did not know the meaning of the dispensing abbreviations such as ‘h.s’, ‘q.d’, ‘sos’ and ‘p.r.n’. The respondents did not know correctly the status of Deltacortil® (Prednisolone, Septran® (Sulfamethoxazole and Fansidar® (Pyrimethamine and Sulfadoxine either as OTC or POM in 26.7% (99, 64.2% (238, and 44.5 % (165 of the cases, respectively. There was a significant difference (p=0.05 in knowledge of dispensers regarding storage temperature, prescription terminologies and status of medicines having different level of qualification and experience.Conclusions: The overall knowledge and training of dispensers working at community pharmacies is inadequate in Pakistan. However, pharmacists had relatively

  5. Qualification, knowledge and experience of dispensers working at community pharmacies in Pakistan.

    Science.gov (United States)

    Hussain, Azhar; Ibrahim, Mohamed Izham M

    2011-04-01

    Pharmacies are managed by a variety of dispensers in terms of qualification, knowledge and experience in Pakistan. The study aimed to document the state of knowledge, experience and qualification of dispensers working at community pharmacies in Pakistan. A comparative cross sectional study was conducted at a randomly selected sample of 371 pharmacies in the three cities of Pakistan. A structured questionnaire for data collection was developed and finalized by focused group discussions and pilot testing. The data was coded, entered and analyzed by using SPSS Version 16. Kruskal-Wallis and Mann-Whitney tests (p≤0.05) were performed to find out differences. Out of total sample of 371 pharmacies, 31.8 % (118) were in Islamabad, 32.4 % (120) in Peshawar and 35.8 % (133) were in Lahore. Fifty percent of the respondents had correct knowledge of range of room temperature at which medicines should be stored. Only 11.1% (41) of the respondents knew about OTC (over the counter drugs) which can be sold without prescription while 5.9 % (22) of the respondents were aware of POM (prescription only medicines) which can be only sold on a valid prescription. While 87.6% (325), 88.1% (327), 58.7% (318) and 95.7 % (355) of the respondents did not know the meaning of the dispensing abbreviations such as 'h.s', 'q.d', 'sos' and 'p.r.n'. The respondents did not know correctly the status of Deltacortil® (Prednisolone), Septran® (Sulfamethoxazole) and Fansidar® (Pyrimethamine and Sulfadoxine) either as OTC or POM in 26.7% (99), 64.2% (238), and 44.5 % (165) of the cases, respectively. There was a significant difference (p≤0.05) in knowledge of dispensers regarding storage temperature, prescription terminologies and status of medicines having different level of qualification and experience. The overall knowledge and training of dispensers working at community pharmacies is inadequate in Pakistan. However, pharmacists had relatively better knowledge regarding storage temperature

  6. Flight Qualification of the NASA's Super Pressure Balloon

    Science.gov (United States)

    Cathey, Henry; Said, Magdi; Fairbrother, Debora

    Designs of new balloons to support space science require a number of actual flights under various flight conditions to qualify them to as standard balloon flight offerings to the science community. Development of the new Super Pressure Balloon for the National Aeronautics and Space Administration’s Balloon Program Office has entailed employing new design, analysis, and production techniques to advance the state of the art. Some of these advances have been evolutionary steps and some have been revolutionary steps requiring a maturing understanding of the materials, designs, and manufacturing approaches. The NASA Super Pressure Balloon development end goal is to produce a flight vehicle that is qualified to carry a ton of science instrumentation, at an altitude greater than 33 km while maintaining a near constant pressure altitude for extended periods of up to 100 days, and at any latitude on the globe. The NASA’s Balloon Program Office has pursued this development in a carefully executed incremental approach by gradually increasing payload carrying capability and increasing balloon volume to reach these end goal. A very successful test flight of a ~200,700 m3 balloon was launch in late 2008 from Antarctica. This balloon flew for over 54 days at a constant altitude and circled the Antarctic continent almost three times. A larger balloon was flown from Antarctica in early 2011. This ~422,400 m3 flew at a constant altitude for 22 days making one circuit around Antarctica. Although the performance was nominal, the flight was terminated via command to recover high valued assets from the payload. The balloon designed to reach the program goals is a ~532,200 m3 pumpkin shaped Super Pressure Balloon. A test flight of this balloon was launched from the Swedish Space Corporation’s Esrange Balloon Launch Facilities near Kiruna, Sweden on 14 August, 2012. This flight was another success for this development program. Valuable information was gained from this short test

  7. Results from the interim salt disposition program macrobatch 10 tank 21H qualification samples

    Energy Technology Data Exchange (ETDEWEB)

    Peters, T. B. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Bannochie, C. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2017-02-23

    Savannah River National Laboratory (SRNL) analyzed samples from Tank 21H in support of qualification of Macrobatch (Salt Batch) 10 for the Interim Salt Disposition Program (ISDP). This document reports characterization data on the samples of Tank 21H and fulfills the requirements of Deliverable 3 of the Technical Task Request (TTR). Further work will report the results of the Extraction-Scrub-Strip (ESS) testing (Task 5 of the TTR) using the Tank 21H material. Task 4 of the TTR (MST Strike) will not be completed for Salt Batch 10.

  8. Results from the DOE Advanced Gas Reactor Fuel Development and Qualification Program

    Energy Technology Data Exchange (ETDEWEB)

    David Petti

    2014-06-01

    Modular HTGR designs were developed to provide natural safety, which prevents core damage under all design basis accidents and presently envisioned severe accidents. The principle that guides their design concepts is to passively maintain core temperatures below fission product release thresholds under all accident scenarios. This level of fuel performance and fission product retention reduces the radioactive source term by many orders of magnitude and allows potential elimination of the need for evacuation and sheltering beyond a small exclusion area. This level, however, is predicated on exceptionally high fuel fabrication quality and performance under normal operation and accident conditions. Germany produced and demonstrated high quality fuel for their pebble bed HTGRs in the 1980s, but no U.S. manufactured fuel had exhibited equivalent performance prior to the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. The design goal of the modular HTGRs is to allow elimination of an exclusion zone and an emergency planning zone outside the plant boundary fence, typically interpreted as being about 400 meters from the reactor. To achieve this, the reactor design concepts require a level of fuel integrity that is better than that claimed for all prior US manufactured TRISO fuel, by a few orders of magnitude. The improved performance level is about a factor of three better than qualified for German TRISO fuel in the 1980’s. At the start of the AGR program, without a reactor design concept selected, the AGR fuel program selected to qualify fuel to an operating envelope that would bound both pebble bed and prismatic options. This resulted in needing a fuel form that could survive at peak fuel temperatures of 1250°C on a time-averaged basis and high burnups in the range of 150 to 200 GWd/MTHM (metric tons of heavy metal) or 16.4 to 21.8% fissions per initial metal atom (FIMA). Although Germany has demonstrated excellent performance of TRISO-coated UO

  9. Summary of Booster Development and Qualification Report

    Energy Technology Data Exchange (ETDEWEB)

    Francois, Elizabeth G. [Los Alamos National Laboratory; Harry, Herbert H. [Los Alamos National Laboratory; Hartline, Ernest L. [Los Alamos National Laboratory; Hooks, Daniel E. [Los Alamos National Laboratory; Johnson, Carl E. [Los Alamos National Laboratory; Morris, John S. [Los Alamos National Laboratory; Novak, Alan M. [Los Alamos National Laboratory; Ramos, Kyle J. [Los Alamos National Laboratory; Sanders, Victor E. [Los Alamos National Laboratory; Scovel, Christina A. [Los Alamos National Laboratory; Lorenz, Thomas [LLNL; Wright, Mark [AWE; Botcher, Tod [PANTEX; Marx, Erin [NSWC-IHDIV; Gibson, Kevin [NSWC-IHDIV

    2012-06-21

    This report outlines booster development work done at Los Alamos National Laboratory from 2007 to present. The booster is a critical link in the initiation train of explosive assemblies, from complex devices like nuclear weapons to conventional munitions. The booster bridges the gap from a small, relatively sensitive detonator to an insensitive, but massive, main charge. The movement throughout the explosives development community is to use more and more insensitive explosive components. With that, more energy is needed out of the booster. It has to initiate reliably, promptly, powerfully and safely. This report is divided into four sections. The first provides a summary of a collaborative effort between LANL, LLNL, and AWE to identify candidate materials and uniformly develop a testing plan for new boosters. Important parameters and the tests required to measure them were defined. The nature of the collaboration and the specific goals of the participating partners has changed over time, but the booster development plan stands on its own merit as a complete description of the test protocol necessary to compare and qualify booster materials, and is discussed in its entirety in this report. The second section describes a project, which began in 2009 with the Department of Defense to develop replacement booster formulations for PBXN-7. Replacement of PBXN-7 was necessary because it contained Triaminotrinitrobenzene (TATB), which was becoming unavailable to the DoD and because it contained Cyclotrimethylenetrinitramine (RDX), which was sensitive and toxic. A LANL-developed explosive, Diaminoazoxyfurazan (DAAF), was an important candidate. This project required any replacement formulation be a drop-in replacement in existing munitions. This project was timely, in that it made use of the collaborative booster development project, and had the additional constraint of matching shock sensitivity. Additionally it needed to be a safety improvement, and a performance

  10. Updated Liquid Secondary Waste Grout Formulation and Preliminary Waste Form Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Saslow, Sarah A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Um, Wooyong [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Russell, Renee L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wang, Guohui [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Asmussen, Robert M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sahajpal, Rahul [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-07-01

    This report describes the results from liquid secondary waste grout (LSWG) formulation and cementitious waste form qualification tests performed by Pacific Northwest National Laboratory (PNNL) for Washington River Protection Solutions, LLC (WRPS). New formulations for preparing a cementitious waste form from a high-sulfate liquid secondary waste stream simulant, developed for Effluent Management Facility (EMF) process condensates merged with low activity waste (LAW) caustic scrubber, and the release of key constituents (e.g. 99Tc and 129I) from these monoliths were evaluated. This work supports a technology development program to address the technology needs for Hanford Site Effluent Treatment Facility (ETF) liquid secondary waste (LSW) solidification and supports future Direct Feed Low-Activity Waste (DFLAW) operations. High-priority activities included simulant development, LSWG formulation, and waste form qualification. The work contained within this report relates to waste form development and testing and does not directly support the 2017 integrated disposal facility (IDF) performance assessment (PA). However, this work contains valuable information for use in PA maintenance past FY17, and for future waste form development efforts. The provided data should be used by (i) cementitious waste form scientists to further understanding of cementitious dissolution behavior, (ii) IDF PA modelers who use quantified constituent leachability, effective diffusivity, and partitioning coefficients to advance PA modeling efforts, and (iii) the U.S. Department of Energy (DOE) contractors and decision makers as they assess the IDF PA program. The results obtained help fill existing data gaps, support final selection of a LSWG waste form, and improve the technical defensibility of long-term waste form performance estimates.

  11. Data Qualification Report: Pore Water Data for Use on the Yucca Mountain Project

    Energy Technology Data Exchange (ETDEWEB)

    H. Miller; R. Monks; C. Warren; W. Wowak

    2000-06-09

    Pore water data associated with Data Tracking Number (DTN) No.LL990702804244.100 are referenced in the Analysis and Model Reports (AMRs) prepared to support the Site Recommendation in determining the suitability of the Yucca Mountain, Nevada as a repository for high-level nuclear waste. It has been determined, in accordance with procedure AP-3.15Q Rev. 1, ICN 1, ''Managing Technical Product Inputs'', Attachment 6 , that the DTN-referenced data are used in AMRs that provide a direct calculation of ''Principal Factors'' for the Post-closure Safety Case or Potentially Disruptive Processes or Events. Therefore, in accordance with the requirements of procedure AP-SIII.2Q, Rev 0, ICN 2, ''Qualification of Unqualified Data and the Documentation of Rationale for Accepted Data'', Section 5.3.1 .a, a Data Qualification Report has been prepared for submittal to the Assistant Manager, Office of Project Execution for concurrence. This report summarizes the findings of the Data Qualification Team assembled to evaluate unqualified ''pore water data'' represented by DTN No. LL990702804244.100. This DTN is currently used in the following AMRs: Drift-Scale Coupled Processes (DST and THC Seepage) Models (CRWMS M&O 2000a), Environment of the Surfaces of the Drip Shield and Waste Package Outer Barrier (CRWMS M&O 2000b), and Engineered Barrier System: Physical and Chemical Environment Model (CRWMS M&O 2000c). Mineral composition of pore water submitted to the Technical Data Management System (TDMS) using the subject DTN were acquired data from the analysis pore water samples sent to Lawrence Livermore National Laboratory's (LLNL) by UFA Ventures, Inc. and analyzed by LLNL's Analytical Sciences/Analytical and Nuclear Chemistry Division (ASD). The purpose and scope of the AMRs that reference the subject DTN and the potential application of pore water data is described below. These AMRs use only that

  12. Qualification of the Nippon Instrumentation for use in Measuring Mercury at the Defense Waste Processing Facility

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, T.; Mahannah, R.

    2011-07-05

    The Nippon Mercury/RA-3000 system installed in 221-S M-14 has been qualified for use. The qualification was a side-by-side comparison of the Nippon Mercury/RA-3000 system with the currently used Bacharach Mercury Analyzer. The side-by-side testing included standards for instrument calibration verifications, spiked samples and unspiked samples. The standards were traceable back to the National Institute of Standards and Technology (NIST). The side-by-side work included the analysis of Sludge Receipt and Adjustment Tank (SRAT) Receipt, SRAT Product, and Slurry Mix Evaporator (SME) samples. With the qualification of the Nippon Mercury/RA-3000 system in M-14, the DWPF lab will be able to perform a head to head comparison of a second Nippon Mercury/RA-3000 system once the system is installed. The Defense Waste Processing Facility (DWPF) analyzes receipt and product samples from the Sludge Receipt and Adjustment Tank (SRAT) to determine the mercury (Hg) concentration in the sludge slurry. The SRAT receipt is typically sampled and analyzed for the first ten SRAT batches of a new sludge batch to obtain an average Hg concentration. This average Hg concentration is then used to determine the amount of steam stripping required during the concentration/reflux step of the SRAT cycle to achieve a less than 0.6 wt% Hg in the SRAT product solids. After processing is complete, the SRAT product is sampled and analyzed for mercury to ensure that the mercury concentration does not exceed the 0.45 wt% limit in the Slurry Mix Evaporator (SME). The DWPF Laboratory utilizes Bacharach Analyzers to support these Hg analyses at this facility. These analyzers are more than 10 years old, and they are no longer supported by the manufacturer. Due to these difficulties, the Bacharach Analyzers are to be replaced by new Nippon Mercury/RA-3000 systems. DWPF issued a Technical Task Request (TTR) for the Savannah River National Laboratory (SRNL) to assist in the qualification of the new systems. SRNL

  13. 14 CFR 121.467 - Flight attendant duty period limitations and rest requirements: Domestic, flag, and supplemental...

    Science.gov (United States)

    2010-01-01

    ... AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Aircraft Dispatcher Qualifications and Duty Time Limitations... operations specifications or in addition to that minimum complement, to duty in an aircraft during flight...

  14. Quality assurance, benchmarking, assessment and mutual international recognition of qualifications.

    Science.gov (United States)

    Hobson, R; Rolland, S; Rotgans, J; Schoonheim-Klein, M; Best, H; Chomyszyn-Gajewska, M; Dymock, D; Essop, R; Hupp, J; Kundzina, R; Love, R; Memon, R A; Moola, M; Neumann, L; Ozden, N; Roth, K; Samwel, P; Villavicencio, J; Wright, P; Harzer, W

    2008-02-01

    The aim of this report is to provide guidance to assist in the international convergence of quality assurance, benchmarking and assessment systems to improve dental education. Proposals are developed for mutual recognition of qualifications, to aid international movement and exchange of staff and students including and supporting developing countries. Quality assurance is the responsibility of all staff involved in dental education and involves three levels: internal, institutional and external. Benchmarking information provides a subject framework. Benchmarks are useful for a variety of purposes including design and validation of programmes, examination and review; they can also strengthen the accreditation process undertaken by professional and statutory bodies. Benchmark information can be used by institutions as part of their programme approval process, to set degree standards. The standards should be developed by the dental academic community through formal groups of experts. Assessment outcomes of student learning are a measure of the quality of the learning programme. The goal of an effective assessment strategy should be that it provides the starting point for students to adopt a positive approach to effective and competent practice, reflective and lifelong learning. All assessment methods should be evidence based or based upon research. Mutual recognition of professional qualifications means that qualifications gained in one country (the home country) are recognized in another country (the host country). It empowers movement of skilled workers, which can help resolve skills shortages within participating countries. These proposals are not intended to be either exhaustive or prescriptive; they are purely for guidance and derived from the identification of what is perceived to be 'best practice'.

  15. ELIMINATION OF THE CHARACTERIZATION OF DWPF POUR STREAM SAMPLE AND THE GLASS FABRICATION AND TESTING OF THE DWPF SLUDGE BATCH QUALIFICATION SAMPLE

    Energy Technology Data Exchange (ETDEWEB)

    Amoroso, J.; Peeler, D.; Edwards, T.

    2012-05-11

    contrast, the variability study has significantly added value to the DWPF's qualification strategy. The variability study has evolved to become the primary aspect of the DWPF's compliance strategy as it has been shown to be versatile and capable of adapting to the DWPF's various and diverse waste streams and blending strategies. The variability study, which aims to ensure durability requirements and the PCT and chemical composition correlations are valid for the compositional region to be processed at the DWPF, must continue to be performed. Due to the importance of the variability study and its place in the DWPF's qualification strategy, it will also be discussed in this report. An analysis of historical data and Production Records indicated that the recommendation of the Six Sigma team to eliminate all characterization of pour stream glass samples and the glass fabrication and PCT performed with the qualification glass does not compromise the DWPF's current compliance plan. Furthermore, the DWPF should continue to produce an acceptable waste form following the remaining elements of the Glass Product Control Program; regardless of a sludge-only or coupled operations strategy. If the DWPF does decide to eliminate the characterization of pour stream samples, pour stream samples should continue to be collected for archival reasons, which would allow testing to be performed should any issues arise or new repository test methods be developed.

  16. Reliability Evaluation of Concentrator Photovoltaic Modules per IEC Qualification Specifications

    Energy Technology Data Exchange (ETDEWEB)

    Tamizhmani, Govindasamy

    2012-12-05

    This project is related to the qualification testing of new generation CPV (concentrator photovoltaics) modules at lower testing costs and lower turnaround time. In this project, the first testing program was completed for two CPV manufacturers, the second testing program was completed for two manufacturers at 65% of the actual testing cost and at less than 3 months of testing turnaround time and the third testing program was completed for two manufacturers at 65% of the actual testing cost and at less than 3 months of testing turnaround time. Due to their financial situation and restructuring, Amonix (one of the CPV manufacturers) intermittently terminated the test programs.

  17. Next Generation Qualification: Kinemetrics STS-5A Seismometer Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Merchant, Bion John [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Slad, George William [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-10-01

    Sandia National Laboratories has tested and evaluated two seismometers, the STS-5A, manufactured by Kinemetrics. These seismometers measure three axes of broadband ground velocity using a UVW configuration with feedback control in a mechanically levelled borehole package. The purpose of the seismometer evaluation was to determine a measured sensitivity, response, self-noise, dynamic range, and self-calibration ability. The Kinemetrics STS-5A seismometers are being evaluated for the U.S. Air Force as part of their Next Generation Qualification effort.

  18. Design, Analysis and Qualification of Elevon for Reusable Launch Vehicle

    Science.gov (United States)

    Tiwari, S. B.; Suresh, R.; Krishnadasan, C. K.

    2017-12-01

    Reusable launch vehicle technology demonstrator is configured as a winged body vehicle, designed to fly in hypersonic, supersonic and subsonic regimes. The vehicle will be boosted to hypersonic speeds after which the winged body separates and descends using aerodynamic control. The aerodynamic control is achieved using the control surfaces mainly the rudder and the elevon. Elevons are deflected for pitch and roll control of the vehicle at various flight conditions. Elevons are subjected to aerodynamic, thermal and inertial loads during the flight. This paper gives details about the configuration, design, qualification and flight validation of elevon for Reusable Launch Vehicle.

  19. Design, Analysis and Qualification of Elevon for Reusable Launch Vehicle

    Science.gov (United States)

    Tiwari, S. B.; Suresh, R.; Krishnadasan, C. K.

    2017-11-01

    Reusable launch vehicle technology demonstrator is configured as a winged body vehicle, designed to fly in hypersonic, supersonic and subsonic regimes. The vehicle will be boosted to hypersonic speeds after which the winged body separates and descends using aerodynamic control. The aerodynamic control is achieved using the control surfaces mainly the rudder and the elevon. Elevons are deflected for pitch and roll control of the vehicle at various flight conditions. Elevons are subjected to aerodynamic, thermal and inertial loads during the flight. This paper gives details about the configuration, design, qualification and flight validation of elevon for Reusable Launch Vehicle.

  20. CEA studies and qualifications prior to the JT-60SA TF coils manufacture

    Energy Technology Data Exchange (ETDEWEB)

    Decool, P., E-mail: patrick.decool@cea.fr; Cloez, H.; Gros, G.; Jiolat, G.; Maréchal, J.L.; Torre, A.; Verger, J.M.

    2013-10-15

    Following the first conceptual design activity in which the general design of the JT-60SA TF system was defined in agreement with all the participants in the project (CEA, ENEA, F4E), a second phase dealing with the detailed design was engaged by each of the voluntary contributors. For the French part which includes the procurement of 9 of the TF winding packs and their integration in the casing, an industrial contract was signed mid 2011 with Alstom (France). Several actions have been carried out to prepare the manufacturing phase. To precisely define one of the main interfaces which is the temporary electrical connection of the coils to the current leads during cold test in the CEA facility as well as their final connection to the feeders at the Naka site, a design compatible with both requirements was developed by CEA, supported by the previous developments led on the joints and assembly techniques. In addition to prepare the coils manufacture, hydraulic qualification was led on the first conductor qualification length to set the parameters which will be used by the coils manufacturer for conductor acceptance. At last, mechanical characterizations of both the conductor and of the empty compacted jacket were performed in order to define as precisely as possible the elastic and plastic properties of these components. These are crucial properties used during the bending process which is one of the most important operations during the winding pack manufacture. These data will be very helpful for the winding machine parameters settings as well as for designing the local bending tooling needed to shape the conductors extremities at the connection area and at the double pancakes joggles.