WorldWideScience

Sample records for secret service official

  1. 78 FR 22151 - Fees for Official Inspection and Official Weighing Services Under the United States Grain...

    Science.gov (United States)

    2013-04-15

    ... Inspection Service (FGIS) with the authority to charge and collect reasonable fees to cover the cost of performing official services. The fees also cover the costs associated with managing the program. After a... associated administrative and supervisory costs. The fees for official inspection and weighing services were...

  2. 78 FR 2627 - Fees for Official Inspection and Official Weighing Services Under the United States Grain...

    Science.gov (United States)

    2013-01-14

    ... authority to charge and collect reasonable fees to cover the cost of performing official services. These fees also cover the costs associated with managing the program. After a financial review of GIPSA's Fees for Official Inspection and Weighing Services, including a comparison of the costs and revenues...

  3. Ionizing radiation in secret services' conspirative actions

    International Nuclear Information System (INIS)

    Vogel, H.; Lotz, P.; Vogel, B.

    2007-01-01

    Introduction: The death of Litvinenko has been reported by the media. It has raised the question whether this case had been unique. The fall of the wall has allowed a glimpse in the planning and comporting of a secret service. Material and method: Documents of the secret service of the former German democratic republic (GDR), books of defectors, and media reports about secret service actions with radiating substances have been analyzed. Results: Since decades, secret services have been using radioactive nuclides and radiation for their tasks. Several killings with radiation have been reported. A complicated logistic had been developed. Conclusion: Only singular cases of the employment of radiating substances have become known. It is probable that the majority rests unknown. Government support seems necessary in secret services' conspirative actions with radiating substance

  4. Ionizing radiation in secret services' conspirative actions

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, H. [Asklepios Klinik St. Georg, Roentgenabteilung, Lohmuehlenstrasse 5, 20099 Hamburg (Germany)], E-mail: Hermann.vogel@ak-stgeorg.lbk-hh.de; Lotz, P.; Vogel, B. [Asklepios Klinik St. Georg, Roentgenabteilung, Lohmuehlenstrasse 5, 20099 Hamburg (Germany)

    2007-08-15

    Introduction: The death of Litvinenko has been reported by the media. It has raised the question whether this case had been unique. The fall of the wall has allowed a glimpse in the planning and comporting of a secret service. Material and method: Documents of the secret service of the former German democratic republic (GDR), books of defectors, and media reports about secret service actions with radiating substances have been analyzed. Results: Since decades, secret services have been using radioactive nuclides and radiation for their tasks. Several killings with radiation have been reported. A complicated logistic had been developed. Conclusion: Only singular cases of the employment of radiating substances have become known. It is probable that the majority rests unknown. Government support seems necessary in secret services' conspirative actions with radiating substance.

  5. CRIMES AGAINST OFFICIAL DUTY IN THE REPUBLIC OF MACEDONIA

    Directory of Open Access Journals (Sweden)

    Darko Majhosev

    2015-07-01

    Full Text Available The paper analyzes the legal provisions of the Criminal Code of the Republic of Macedonia relating to crimes against official duty. Crimes against official duty represent a group of criminal offenses that occupy a special place in criminal law. This kind of crimes is also called civil servants crimes, that is, they are defined as a violation of duty made by an official in performing his/her official duty. In this paper we will analyze all articles of the Criminal Code that regulate the group of criminal offenses against official duty. Most frequent cases of misuse of official duty are cases of misuse of official position and authorization, unprincipled operation within the service, defraud in the service, receiving a bribe, giving a bribe, unlawful mediation, disclosing an official secret, falsifying an official document and other. The paper will define the terms official and responsible person. In the context of the paper we will show the research referring to the number of registered and accused of crimes against official duty in the Republic of Macedonia in the period from 2004 to 2013.

  6. 7 CFR 1900.155 - Designating the processing/servicing official.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Designating the processing/servicing official. 1900.155 Section 1900.155 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE SERVICE, RURAL UTILITIES SERVICE, AND FARM SERVICE AGENCY...

  7. 31 CFR 401.1 - Secret Service agents authorized to make seizures.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Secret Service agents authorized to... Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF VESSELS, VEHICLES... Secret Service agents authorized to make seizures. All officers of the U.S. Secret Service engaged in the...

  8. 18 CFR 3a.12 - Authority to classify official information.

    Science.gov (United States)

    2010-04-01

    ... efficient administration. (b) The authority to classify information or material originally as Top Secret is... classify information or material originally as Secret is exercised only by: (1) Officials who have Top... information or material originally as Confidential is exercised by officials who have Top Secret or Secret...

  9. 31 CFR Appendix D to Subpart A of... - United States Secret Service

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false United States Secret Service D...—United States Secret Service 1. In general. This appendix applies to the United States Secret Service. 2. Public reading room. The United States Secret Service will provide a room on an ad hoc basis when...

  10. 78 FR 52431 - Amendments to ONRR's Service of Official Correspondence

    Science.gov (United States)

    2013-08-23

    ... service is effected; (3) Private mailing service (e.g., United Parcel Service, or Federal Express), with...-2013-0001; DS63610300 DR2PS0000.CH7000 134D0102R2] RIN 1012-AA14 Amendments to ONRR's Service of...), Interior. ACTION: Direct final rule. SUMMARY: This rule will update the Service of Official Correspondence...

  11. 14 CFR 121.550 - Secret Service Agents: Admission to flight deck.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Secret Service Agents: Admission to flight... OPERATING REQUIREMENTS: DOMESTIC, FLAG, AND SUPPLEMENTAL OPERATIONS Flight Operations § 121.550 Secret Service Agents: Admission to flight deck. Whenever an Agent of the Secret Service who is assigned the duty...

  12. 31 CFR 406.1 - Secret Service officers authorized to make seizures of gold.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Secret Service officers authorized to... and Finance (Continued) SECRET SERVICE, DEPARTMENT OF THE TREASURY SEIZURE AND FORFEITURE OF GOLD FOR VIOLATIONS OF GOLD RESERVE ACT OF 1934 AND GOLD REGULATIONS § 406.1 Secret Service officers authorized to...

  13. [Links between non-professional agents and the official Veterinary Services in sub-Saharan Africa].

    Science.gov (United States)

    Diop, B A; Bessin, R

    2004-04-01

    Para-professional agents known as auxiliaries, or community animal health workers, provide low-cost basic veterinary services to communities of livestock producers. A 2003 survey of 16 Sub-Saharan African countries, carried out as part of the Pan-African Programme for the Control of Epizootics, showed that in the majority of cases, the official Veterinary Services have no (or very few) links with the auxiliaries, although they are well aware of their existence and in some cases the auxiliaries have been trained by officials of the Veterinary Services. However, there are isolated cases of countries establishing more formal links, for example, recognising the status of an auxiliary, recognising auxiliaries with no definition of a status, attaching auxiliaries to Veterinary Service staff, establishing agreements for the provision of auxiliary services through livestock producer associations, harmonising auxiliary training programmes, issuing professional auxiliary cards, and setting up a consultation framework on the issue of auxiliaries. Unlike private veterinarians, agents of the official services do not generally perceive auxiliaries as competitors, and sometimes collaboration develops at this level. The authors propose several measures to improve links between the official Veterinary Services and auxiliaries, as follows: the fields of competence of auxiliaries should be defined and their curriculum harmonised, the status of auxiliaries should be recognised, a monitoring and assessment mechanism should be established at senior level in the Veterinary Services, training for livestock producers should be improved.

  14. [Secret drug tribulations and French legislation].

    Science.gov (United States)

    Charlot, Colette

    2002-01-01

    From an official Montpellier prefecture paper of 18th century, we are interested in a secret drug from Provence origin: the Irroë powder. This purgative will pass from "secret" drug status to "patent" drug. It's notoriety will come from its arrival to Paris. The law of 21th germinal year XI, the decret of 25 prairial year XIII and this of 18th 1810 imposed to give the drug composition to an official status; that examined and permit it's sale. This secret will be produce for half century.

  15. 50 CFR 260.97 - Conditions for providing fishery products inspection service at official establishments.

    Science.gov (United States)

    2010-10-01

    ... processed foods and/or components thereof; (10) Furnish and provide laundry service, as required by NMFS... inspection service at official establishments. 260.97 Section 260.97 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE PROCESSED FISHERY...

  16. 5 CFR 3101.111 - Additional rules for United States Secret Service employees. [Reserved

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Additional rules for United States Secret Service employees. [Reserved] 3101.111 Section 3101.111 Administrative Personnel DEPARTMENT OF THE....111 Additional rules for United States Secret Service employees. [Reserved] ...

  17. 76 FR 66937 - Privacy Act of 1974; Department of Homeland Security/United States Secret Service-003 Non...

    Science.gov (United States)

    2011-10-28

    ... 1974; Department of Homeland Security/United States Secret Service--003 Non-Criminal Investigation... Security/United States Secret Service--003 Non-Criminal Investigation Information System.'' As a result of... Secret Service, 245 Murray Lane SW., Building T-5, Washington, DC 20223. For privacy issues please...

  18. [Relations between official and private veterinary services in epidemiology and the control of contagious diseases].

    Science.gov (United States)

    Moura, J A; Bedoya, M; Agudelo, M P

    2004-04-01

    Growing budget restrictions in many countries have meant that official Veterinary Services cannot assume responsibility for any new activities. The natural reaction is to turn to private veterinary services to provide the support needed to strengthen the control and surveillance of priority diseases and thereby support the development of the livestock sector and the establishment of safe international trade. In this context, official Veterinary Services must work together with private veterinarians, delegating various technical animal health activities, so that they may focus their efforts on those tasks that cannot be delegated: standardisation, control, auditing, general system co-ordination, epidemiological surveillance, etc., as well as organising veterinary policy in order to make best use of budget resources. For these relations to be efficient, a dynamic, two-way epidemiological information mechanism must be created, whereby private veterinarians periodically keep governments informed, on the basis of an agreed methodology. Moreover, the official Veterinary Services must systematically transmit information on List A and B diseases of the OIE (World organisation for animal health), and perform detailed analyses of epidemiologically significant events. The article proposes the establishment of relations between public and private veterinary services as a way in which to provide the livestock sector with the health and hygiene conditions that are necessary for effective disease control, which in turn provides greater security for international trade and increased consumer protection.

  19. 32 CFR 1605.28 - Signing official papers.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Signing official papers. 1605.28 Section 1605.28 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM SELECTIVE SERVICE SYSTEM ORGANIZATION District Appeal Boards § 1605.28 Signing official papers. Official documents issued...

  20. 32 CFR 1605.59 - Signing official papers.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Signing official papers. 1605.59 Section 1605.59 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM SELECTIVE SERVICE SYSTEM ORGANIZATION Local Boards § 1605.59 Signing official papers. Official papers issued by a local...

  1. Legal Regimes of Official Information in Ukraine

    Directory of Open Access Journals (Sweden)

    Serhii Yesimov

    2018-04-01

    Full Text Available In the article on the basis of the methodology of system analysis the legal nature and sources of legal regulation of the legal regime of official information in Ukraine in the conditions of adaptation of Ukrainian legislation to the legislation of the European Union are considered. A comparative legal analysis of official information in the public-law and private-law spheres in the context of legal regimes of restricted information, confidential information and information classified as state secrets has been conducted.

  2. 9 CFR 352.3 - Application by official exotic animal establishment for inspection services.

    Science.gov (United States)

    2010-01-01

    .... (a) Any person desiring to process an exotic animal, exotic animal carcasses, exotic animal meat and... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Application by official exotic animal establishment for inspection services. 352.3 Section 352.3 Animals and Animal Products FOOD SAFETY AND...

  3. 76 FR 66940 - Privacy Act of 1974; Department of Homeland Security/United States Secret Service-004 Protection...

    Science.gov (United States)

    2011-10-28

    ... DEPARTMENT OF HOMELAND SECURITY Office of the Secretary [Docket No. DHS-2011-0083] Privacy Act of 1974; Department of Homeland Security/United States Secret Service--004 Protection Information System... Security (DHS)/United States Secret Service (USSS)-004 System name: DHS/USSS-004 Protection Information...

  4. Official Publications Section. Collections and Services Division. Papers.

    Science.gov (United States)

    International Federation of Library Associations, The Hague (Netherlands).

    Papers on official publications (government documents), automation, and electronic publishing, which were presented at the 1983 International Federation of Library Associations (IFLA) conference, include: (1) "The Automation of Documentation as It Relates to Official Publications and Its Importance in a Developing Country" by Ahmed…

  5. 7 CFR 54.12 - Financial interest of official grader.

    Science.gov (United States)

    2010-01-01

    ... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS... Service § 54.12 Financial interest of official grader. No official grader shall grade or determine... 7 Agriculture 3 2010-01-01 2010-01-01 false Financial interest of official grader. 54.12 Section...

  6. NAGWS Softball Guide 1991: Official Rules/Officiating.

    Science.gov (United States)

    Matson, Janis

    This softball guide presents information on: the National Association for Girls and Women in Sport (NAGWS), rule modifications, softball playing rules, and officiating. Section 1 explains the purpose, beliefs, and services of the NAGWS; provides information on the association's committees and membership application; and explains use of the…

  7. 7 CFR 51.17 - Official sampling.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Official sampling. 51.17 Section 51.17 Agriculture... Inspection Service § 51.17 Official sampling. Samples may be officially drawn by any duly authorized... time and place of the sampling and the brands or other identifying marks of the containers from which...

  8. Official showguide

    International Nuclear Information System (INIS)

    1998-01-01

    This national petroleum show was an opportunity for companies from around the world to showcase their products and services and to demonstrate the world's best in energy technologies. This official showguide lists the technical presentations made at the show, and provides an exhibitor profile for each company, including the company name, address, phone and fax number, and a brief description of the product or services they offer. An alphabetical listing of approximately 900 companies and their booth locations is also included

  9. 45 CFR 99.27 - Official transcript.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Official transcript. 99.27 Section 99.27 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROCEDURE FOR HEARINGS FOR THE CHILD CARE AND DEVELOPMENT FUND Hearing Procedures § 99.27 Official transcript. The Department will...

  10. The good, the bad, and the severely mentally ill: Official and informal labels as organizational resources in community mental health services.

    Science.gov (United States)

    Dobransky, Kerry

    2009-09-01

    Research on labeling mental illness has focused relatively little attention on practical organizational concerns in the process of labeling in community mental health services. This paper examines this issue through an ethnographic study of two multi-service community mental health services organizations for people labeled severely and persistently mentally ill in the Midwest United States. The findings show that the labeling process is structured by cultural and policy environments in which mental health services are able to provide resources otherwise difficult to obtain. Within organizations, official labels can be applied for reasons other than clinical practice; they channel resources to both organizations and clients. Informal organizational labels regarding client mental illness are not tethered to the bureaucratic apparatus granting access to and paying for services. Instead, they reflect workers' real assessments of clients, which can differ from official ones. These informal labels determine how organizations deal with clients when rules and routines are violated.

  11. 7 CFR 91.102 - Form of official identification symbols.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Form of official identification symbols. 91.102... LABORATORY TESTING PROGRAMS SERVICES AND GENERAL INFORMATION Designation of Approved Symbols for Identification of Commodities Officially Tested By AMS § 91.102 Form of official identification symbols. Two...

  12. 9 CFR 325.7 - Shipment of products requiring special supervision between official establishments under official...

    Science.gov (United States)

    2010-01-01

    ... Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY ORGANIZATION AND... subchapter, in railroad cars, trucks, or other means of conveyance sealed with the official seal of the...

  13. 39 CFR 601.108 - SDR Official disagreement resolution.

    Science.gov (United States)

    2010-07-01

    ... purchasing decisions and the administrative records concerning those decisions. All disagreements under § 601... time to lodge a disagreement lapses. (e) Disagreement decision process. The SDR Official will promptly...: INTELLECTUAL PROPERTY RIGHTS OTHER THAN PATENTS PURCHASING OF PROPERTY AND SERVICES § 601.108 SDR Official...

  14. 42 CFR 73.9 - Responsible Official.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Responsible Official. 73.9 Section 73.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES QUARANTINE, INSPECTION, LICENSING... Attorney General, (2) Be familiar with the requirements of this part, (3) Have authority and responsibility...

  15. Learning, Official Languages and Employment Equity Advisor ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job Summary Plans and coordinates human resources services in the areas of Learning, Official Languages (OL) and Employment Equity (EE) while ensuring that management's needs are met. Provides operational services and advises managers and employees in determining their needs, analyzing problems, ...

  16. An Efficient Secret Key Homomorphic Encryption Used in Image Processing Service

    Directory of Open Access Journals (Sweden)

    Pan Yang

    2017-01-01

    Full Text Available Homomorphic encryption can protect user’s privacy when operating on user’s data in cloud computing. But it is not practical for wide using as the data and services types in cloud computing are diverse. Among these data types, digital image is an important personal data for users. There are also many image processing services in cloud computing. To protect user’s privacy in these services, this paper proposed a scheme using homomorphic encryption in image processing. Firstly, a secret key homomorphic encryption (IGHE was constructed for encrypting image. IGHE can operate on encrypted floating numbers efficiently to adapt to the image processing service. Then, by translating the traditional image processing methods into the operations on encrypted pixels, the encrypted image can be processed homomorphically. That is, service can process the encrypted image directly, and the result after decryption is the same as processing the plain image. To illustrate our scheme, three common image processing instances were given in this paper. The experiments show that our scheme is secure, correct, and efficient enough to be used in practical image processing applications.

  17. British Television and Official Film, 1946-1951.

    Science.gov (United States)

    Wildy, Tom

    1988-01-01

    Discusses the relationships between the British Government's Information Services and both the British Broadcasting Corporation (BBC) and the commercial film trade after the BBC's television service resumed independent broadcasts in 1946. Examines proposals for using television as an alternative outlet for commercial and official films. (GEA)

  18. 22 CFR 1421.15 - Secret ballot.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Secret ballot. 1421.15 Section 1421.15 Foreign Relations FOREIGN SERVICE LABOR RELATIONS BOARD; FEDERAL LABOR RELATIONS AUTHORITY; GENERAL COUNSEL OF THE... THIS SUBCHAPTER § 1421.15 Secret ballot. Secret ballot means the expression by ballot, voting machine...

  19. 9 CFR 302.3 - Livestock and products entering official establishments.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Livestock and products entering official establishments. 302.3 Section 302.3 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE... Livestock and products entering official establishments. All livestock and all products entering any...

  20. Official Statistics and Statistics Education: Bridging the Gap

    Directory of Open Access Journals (Sweden)

    Gal Iddo

    2017-03-01

    Full Text Available This article aims to challenge official statistics providers and statistics educators to ponder on how to help non-specialist adult users of statistics develop those aspects of statistical literacy that pertain to official statistics. We first document the gap in the literature in terms of the conceptual basis and educational materials needed for such an undertaking. We then review skills and competencies that may help adults to make sense of statistical information in areas of importance to society. Based on this review, we identify six elements related to official statistics about which non-specialist adult users should possess knowledge in order to be considered literate in official statistics: (1 the system of official statistics and its work principles; (2 the nature of statistics about society; (3 indicators; (4 statistical techniques and big ideas; (5 research methods and data sources; and (6 awareness and skills for citizens’ access to statistical reports. Based on this ad hoc typology, we discuss directions that official statistics providers, in cooperation with statistics educators, could take in order to (1 advance the conceptualization of skills needed to understand official statistics, and (2 expand educational activities and services, specifically by developing a collaborative digital textbook and a modular online course, to improve public capacity for understanding of official statistics.

  1. National Statistical Commission and Indian Official Statistics*

    Indian Academy of Sciences (India)

    IAS Admin

    a good collection of official statistics of that time. With more .... statistical agencies and institutions to provide details of statistical activities .... ing several training programmes. .... ful completion of Indian Statistical Service examinations, the.

  2. 7 CFR 53.14 - Financial interest of official grader.

    Science.gov (United States)

    2010-01-01

    ... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS... (CONTINUED) LIVESTOCK (GRADING, CERTIFICATION, AND STANDARDS) Regulations Service § 53.14 Financial interest... 7 Agriculture 3 2010-01-01 2010-01-01 false Financial interest of official grader. 53.14 Section...

  3. 9 CFR 355.8 - Official number.

    Science.gov (United States)

    2010-01-01

    ... CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER CARNIVORA; INSPECTION, CERTIFICATION, AND... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Official number. 355.8 Section 355.8 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE AGENCY...

  4. A review of official data obtained from dog control records generated by the dog control service of county cork, Ireland during 2007

    Science.gov (United States)

    2012-01-01

    Background There are no peer reviewed data on dog control records from an official agency in Ireland. In order to address this, a total of 2,669 official dog control service records generated during 2007 by Cork County Council dog control service were reviewed. Results Over 70 percent of records related to unwanted dogs and dogs not under their owners control. Stray dogs were collected by the service regularly throughout the year but with notable increase in voluntary surrenders by owners from January through to April. The majority of dogs collected or surrendered were male (2:1 ratio), of medium size, described as having a friendly temperament and were not wearing a neck collar. The Crossbreed and Greyhound breeds were more frequently collected as strays, while Greyhounds and German Shepherds were more frequently voluntarily surrendered by their owner. Restricted breeds such as Pit Bull terriers, German Shepherds and Rottweilers were more frequently reported by members of the public for aggressive behaviour while the only restricted breed reported for biting or snapping was the German Shepherd. Conclusions Routine recording of dog control services in County Cork provide data on responsible dog ownership including the licensing of breeds, and surrender of owned dogs and the collection of stray dogs. Data capture and utilisation of dog control services by local authorities has potential to inform policy on responsible dog ownership and education programmes. PMID:22681751

  5. The Rhetorical Algorithm: WikiLeaks and the Elliptical Secrets of Donald J. Trump

    Directory of Open Access Journals (Sweden)

    Atilla Hallsby

    2018-02-01

    Full Text Available Algorithms were a generative force behind many of the leaks and secrets that dominated the 2016 election season. Taking the form of the identity-anonymizing Tor software that protected the identity of leakers, mathematical protocols occupied a prominent place in the secrets generated during the presidential campaign. This essay suggests that the rhetorical trope of ellipsis offers an equally crucial, algorithmic formula for explaining the public production of these secrets and leaks. It then describes the 2016 DNC leak and Donald Trump’s “I love Wikileaks” moment using the trope of ellipsis, which marks a discursive omission or gap in official executive discourse.

  6. 31 CFR 315.1 - Official agencies.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Official agencies. 315.1 Section 315.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE.... Federal Reserve Bank of Kansas City, 925 Grand Avenue, Kansas City, MO 64198 Dallas, San Francisco, Kansas...

  7. 31 CFR 353.1 - Official agencies.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Official agencies. 353.1 Section 353.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE.... Federal Reserve Bank of Kansas City, 925 Grand Avenue, Kansas City, MO 64198 Dallas, San Francisco, Kansas...

  8. 31 CFR 360.1 - Official agencies.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Official agencies. 360.1 Section 360.1 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL SERVICE... Bank of Kansas City, 925 Grand Boulevard, Kansas City, MO 64106 Dallas, San Francisco, Kansas City, St...

  9. Secret-key rates and privacy leakage in biometric systems

    NARCIS (Netherlands)

    Ignatenko, T.

    2009-01-01

    In this thesis both the generation of secret keys from biometric data and the binding of secret keys to biometric data are investigated. These secret keys can be used to regulate access to sensitive data, services, and environments. In a biometric secrecy system a secret key is generated or chosen

  10. 9 CFR 590.35 - Eggs and egg products outside official plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Eggs and egg products outside official plants. 590.35 Section 590.35 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT... official plant and are in violation of this part or any of said Federal Acts or any State or local law...

  11. NAGWS Softball Guide 1989. Official Rules/Officiating.

    Science.gov (United States)

    Matson, Janis

    This booklet, written for coaches of women's softball teams, contains the official National Association for Girls and Women in Sports (NAGWS) rules for the game. Recent rule modifications are included. Statements of philosophy and standards for NAGWS officials are also included. (JD)

  12. Non-official mail

    CERN Multimedia

    2006-01-01

    The Mail Office wishes to remind users of the mail service that the latter is reserved exclusively for the Organization's official mail. Private mail, even if stamped, does not fall into this category, and any mail of this nature found in the 'Outgoing Mail' or 'Départ Courrier' boxes will no longer be collected or accepted by the Meyrin or Prévessin Mail Offices. The Mail Office declines all responsibility in the event of losses, delays or any other problems arising as a result of private mail being placed in these boxes. Thank you for your understanding. The Mail Office

  13. Sports officials and officiating : Science and practice

    NARCIS (Netherlands)

    MacMahon, Clare; Mascarenhas, Duncan; Plessner, Henning; Pizzera, Alexandra; Oudejans, Raôul R D; Raab, Markus

    2014-01-01

    Sports officials (umpires, referees, judges) play a vital role in every sport, and sports governing bodies, fans, and players now expect officials to maintain higher professional standards than ever before. In this ground-breaking book, a team of leading international sport scientists and top level

  14. AWS certified solutions architect official study guide associate exam

    CERN Document Server

    Baron, Joe; Bixler, Tim; Gaut, Biff; Kelly, Kevin E; Senior, Sean; Stamper, John

    2017-01-01

    This is your opportunity to take the next step in your career by expanding and validating your skills on the AWS cloud. AWS has been the frontrunner in cloud computing products and services, and the AWS Certified Solutions Architect Official Study Guide for the Associate exam will get you fully prepared through expert content, and real-world knowledge, key exam essentials, chapter review questions, access to Sybex's interactive online learning environment, and much more. This official study guide, written by AWS experts, covers exam concepts, and provides key review on exam topics, including: * Mapping Multi-Tier Architectures to AWS Services, such as web/app servers, firewalls, caches and load balancers * Understanding managed RDBMS through AWS RDS (MySQL, Oracle, SQL Server, Postgres, Aurora) * Understanding Loose Coupling and Stateless Systems * Comparing Different Consistency Models in AWS Services * Understanding how AWS CloudFront can make your application more cost efficient, faster and secure * Implem...

  15. The principle of public access to official documents in Sweden

    International Nuclear Information System (INIS)

    Persson, I.

    2001-01-01

    In Sweden, access to information is considered one of the cornerstones of the free democratic exchange of views. It is not enough that public authorities give information about their work. Public activities shall be open to the citizens and the media in such a way that they can choose the information they wish to obtain, without having to rely on public information services. An official document is public, it must be kept available to anyone who wishes to peruse it. Official documents are registered in a public register in order to allow to anyone to exercise their right of access to official document. (N.C.)

  16. Sur les usages publics du secret : les archives du Service Secret Communiste Roumain

    Directory of Open Access Journals (Sweden)

    Andi Mihalache

    2009-10-01

    Full Text Available L’étude s’occupe des dossiers de l’ancienne police politique du régime communiste de Roumanie, la Securitate. Il a comme point de départ le fait que la mémoire sociale, le contexte politique et les débats publics actuels influencent la recherche historique, modifiant les perceptions sur le document d’archive. Ce dernier n’est plus vu seulement comme source principale de la recherche historique, devenant outil redoutable dans les disputes électorales, car, en base des informations extraites d’un dossier de la Securitate, l’on peut évincer un adversaire incommode. Se montrant utile à dénoncer la collaboration de quelqu’un sous le régime communiste, le document d’archive a acquis des mises symboliques imprévues, étant caché, protégé, volé, racheté, truqué, perdu et redécouvert à commande. Toutes ces pratiques compromettent de plus en plus les chances des historiens de reconstituer de manière crédible l’histoire récente des Roumains. On obtient difficilement l’accès aux dossiers de la Securitate, la patrimonialisation excessive des documents - en vérité leur trésorisation - étant conséquence directe du prestige idéologique et social que le secret détenait au temps communiste.This article focuses on the Securitate files as a political stake, but also as first rank sources for academic research, not from the current perspective of recent history, but from that of cultural history. In post-communist Romania, silence is the secret’s poor relative and confidentiality its respectable form. Ironically or not, we could state that in our country the secrets of communist repression are literally protected by law. The secret is an unbidden, illegitimate competence. In its ethics it does not matter what is good and what is bad, what is true and what is false. The main interest is what is said and what isn’t. The secret being a convention, a pact, the gesture of not saying seems to be more important than

  17. Management of Patients Who Make Threats Against Elected Officials: A Case Report

    Directory of Open Access Journals (Sweden)

    Paulina Riess

    2018-05-01

    Full Text Available Federal law makes it a crime to threaten the President of the United States. The Secret Service conducts thousands of violence risk assessments each year. Literature suggests that 75% of individuals who make threats have been diagnosed with a mental illness (1. Studies show that prominent symptoms in presidential assassins include persecutory and grandiose delusions, hence falling into the category of psychotic disorders. We present a case of a patient diagnosed with Schizoaffective Disorder brought to CPEP (Comprehensive Psychiatric Emergency Program by the Secret Service for repeatedly dialing 911 and making threats to the President. In the past year the patient had been hospitalized three times for similar behavior. Initial presentation included acute symptoms of psychosis and mania including persecutory delusions, command auditory hallucinations, grandiosity, and thought disorder. Clinicians were faced with unique challenges and consulted the forensic service to navigate the role of the Secret Service and develop a plan to prevent future episodes. The patient was discharged with a court order for treatment, long acting medication, as well as an outpatient appointment. The treatment plan has been effective and the Secret Service has ceased their investigation. We aim to explore issues in patient confidentiality, duty to both report and protect. We will also provide strategies and recommendations for such patients on the inpatient unit.

  18. AN ASSESSMENT OF THE NEED OF POLICE OFFICIALS FOR TRAUMA INTERVENTION PROGRAMMES – A QUALITATIVE APPROACH

    Directory of Open Access Journals (Sweden)

    Strydom, Herman

    2015-09-01

    Full Text Available lOfficials in the South African Police Service (SAPS are exposed to multiple traumatic incidents. The effect of such exposure is aggravated by various contributing factors that may cause intense trauma for the individual, family members and the police service. The risk factors include post-traumatic stress, acute stress, depression, alcohol abuse, suicide and impaired productivity. It is therefore important that officials have direct access to support. The efficacy of the present trauma intervention programmes in the SAPS is questioned, because despite their implementation police officials still present high levels of acute and behavioural problems

  19. The task of official personal monitoring in Germany using electronic dosimetry systems

    International Nuclear Information System (INIS)

    Huebner, Stephan; Wahl, Wolfgang; Busch, Frank; Martini, Ekkehard

    2008-01-01

    Full text: Since the establishment of the first German personal monitoring services as competent measuring bodies in the year 1952, official personal dosimetry is carried out using passive dosimeters such as film batches, RPL- and TL-dosimeters solely. On the other hand, electronic dosimeters are in use in some big institutions like Nuclear Power Plants, hospitals or industrial units for operational purposes. In most cases, these dosimeters are regulated by competent authorities. For more than 20 years electronic dosimeters proved their worth of being appropriate personal dosimeters. Since 2001 concepts to implement electronic personal dosimeters into the official individual monitoring of occupational exposed workers were developed in different research projects. The EU market of personal dosimetry changes to an open and competitive one, the number of outside workers, especially during the outages of Nuclear Power Plants increases, the landscape of customers is getting more and more heterogeneous. Being able to face these tasks of a sustainable personal monitoring requires the introduction of modern electronic dosimeters into to the official monitoring. Doing so, the needed prompt exchange of dose-data between different monitoring services as well as between the customers and the related monitoring service can be warranted. In cooperation with the industry, competent authorities and a research centre a method for official dosimetry using electronic dosimetry systems was developed, realised and tested successfully by the three big monitoring services of Germany. These investigations are supported by the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety. For this purpose a network between customers and monitoring services was built up in order to monitor people, who work in different places related to different measuring bodies in only one period of surveillance. (author)

  20. 7 CFR 54.1017 - Authority to use official identification.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT..., Processing, and Packaging of Livestock and Poultry Products § 54.1017 Authority to use official...

  1. 7 CFR 54.1015 - Official reports, forms, and certificates.

    Science.gov (United States)

    2010-01-01

    ... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT..., Processing, and Packaging of Livestock and Poultry Products § 54.1015 Official reports, forms, and...

  2. 42 CFR 405.215 - Confidential commercial and trade secret information.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Confidential commercial and trade secret information. 405.215 Section 405.215 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... trade secret information. To the extent that CMS relies on confidential commercial or trade secret...

  3. Individual monitoring with official electronic dosemeters in Germany - concepts and reality

    International Nuclear Information System (INIS)

    Martini, E.; Wahl, W.; Huebner, S.; Freynhagen, D.; Staemmler, M.

    2005-01-01

    Full text: Active (electronic) personal dosemeters (APD) are radiometers, which are equipped as active or passive dosimeters. They can directly indicate a dose rate and/or the dose integrated during a certain period (direct-indicating, active electronic personal dosemeters mentioned) or only over a separate reader (direct-selectable, passive electronic personal dosemeters mentioned). A concept is presented for the use of passive or active electronic personal dosemeters in Germany as official dosemeters, e.g. in hospitals. The concept features a net-based approach for secure data communication between readers for passive and active electronic personal dosemeters und the official personal dosimetry monitoring service(s), taking the German policies (StrISchV und RoeV in hospitals) into account. The net-based solution includes a processor controlled interface via TCP/IP connected to the dosimetry reader(s), und reader interfaces, an official interim data bank and all the necessary equipment such as PC, Raid-configuration, USV support, network connection and further details. Investigations have been started to achieve highest-level data manipulation security, data completeness und data correctness. (author)

  4. Finding official British information official publishing in the digital age

    CERN Document Server

    Inman, Jane; Purushothama, B

    2011-01-01

    Examining the different bodies that publish official material, this book describes the types of material published, how it is made available and how it is recorded. Finding Official British Information focuses on the digital availability of official information and considers how much is now freely available on the web and how to locate it as well as addressing issues of web only publishing. It covers public bodies in the UK and includes publications issued by central and local government as well as the devolved assemblies and the many other organisations that issue official publications. Quick 'how to find' section for each area Designed for the non-specialist Covering central and local government, the devolved assemblies and other public bodies in the UK.

  5. Adaptation of occupants with its environment in the official residence (case study: Housing of TNI AD Gaperta)

    Science.gov (United States)

    Nirfalini Aulia, Dwira; Aritonang, Cindy

    2018-03-01

    An official residence is a housing provided by the state and used as a residence occupied by the official duties of officials and civil servants during their service in the city. The property rights of the official residence have limit, only valid while the residents serve in the city. The process of adaptation becomes indispensable because, in the early days of occupying the housing, residents will face a new social environment, which may be different from their previous environment. Furthermore, backgrounds such as economic, cultural, and social factors of each occupant will also determine the adaptation process that occurs. This research aims to find out and analyze adaptation process of the official residence’s dwellers to its environment. This study used the descriptive-qualitative method by interviewing ten occupants who selected by purposive sampling method. Results of research indicated that the most adaptation process occurs adaptation by the reaction such as adding the number of room and service area.

  6. 29 CFR 2703.2 - Designated agency ethics official and alternate designated agency ethics official.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Designated agency ethics official and alternate designated agency ethics official. 2703.2 Section 2703.2 Labor Regulations Relating to Labor (Continued) FEDERAL... agency ethics official and alternate designated agency ethics official. The Chairman shall appoint an...

  7. 31 CFR 0.104 - Designated Agency Ethics Official and Alternate Designated Agency Ethics Official.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Designated Agency Ethics Official and Alternate Designated Agency Ethics Official. 0.104 Section 0.104 Money and Finance: Treasury Office of the... Responsibilities § 0.104 Designated Agency Ethics Official and Alternate Designated Agency Ethics Official. The...

  8. Qatar Airways Official Partner of China Team At 15th Doha Asian Games 2006

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Asian Games was held from Dec.1-15 this year in Qatar's capital Doha,which attracted more than 10,500 athletes and team officials from 45 countries competing in 39sports.As Official Airline of the 15th Asian Games,Qatar Airways delivers its award-winning Five Star service to visitors to the Games,whether they are participating or are spectators.

  9. Must Officials Microblog?

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Nowadays,Twitter-like microblogging is no longer strange for government officials in China.China Youth Daily reported more than 1,300 officials have opened real-name microblogs on Sina microblog. And there are now more than 2,000 microblogs of government

  10. 15 CFR 25.5 - Review by the reviewing official.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Review by the reviewing official. 25.5 Section 25.5 Commerce and Foreign Trade Office of the Secretary of Commerce PROGRAM Fraud Civil Remedies... value of property, services, or other benefits, requested or demanded in violation of § 25.3 of this...

  11. 7 CFR 800.117 - Who shall perform original services.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Who shall perform original services. 800.117 Section... REGULATIONS Original Services § 800.117 Who shall perform original services. (a) General. Original services... official agency is not available on a regular basis to provide original services, and no official agency...

  12. Secret Shopping is an Effective Tool for Identifyings in Library User Experience Local Pattern

    Directory of Open Access Journals (Sweden)

    Kelley Wadson

    2016-12-01

    Full Text Available A Review of: Boyce, C. M. (2015. Secret shopping as user experience assessment tool. Public Services Quarterly, 11(4, 237-253. doi:10.1080/15228959.2015.1084903 Objective – To assess library user experience (UX at two entry-level service desks to determine the need for, and inform the aspects in which to improve, services and staff training. Design – Observational study using secret shopping. Setting – A small, private university in Illinois, United States of America. Subjects – Library employees, comprised primarily of student assistants; and 11 secret shoppers, comprised of 5 faculty members, 4 staff members, and 2 first-year students from the university.

  13. 30 CFR 218.540 - How does MMS serve official correspondence?

    Science.gov (United States)

    2010-07-01

    ... agent; (ii) Any corporate officer; or (iii) The addressee of record shown in the files of any State Secretary; Corporate Commission; Federal or state agency that keeps official records of business entities or... delivery made pursuant to the law of the State in which the service is effected; or (3) Private mailing...

  14. Statistical results 1991-1993 of the Official Personal Dosimetry Service

    International Nuclear Information System (INIS)

    Boerner, E.; Drexler, G.; Wittmann, A.

    1995-01-01

    The report consists of a summary of relevant statistical data in the official personal dosimetry in 1988-1990 for the Federal States of Bavaria, Hesse, Schleswig-Holstein, and Baden-Wuerttemberg. The data are based on the survey of more than 8000 institutions with over 140000 occupational exposed persons and are derived from more than one million single measurements. The report covers informations on the institutions, on the persons as well as dosimetric values. The measuring method is described briefly with respect to dosimeters used, their range and the interpretation of values. Information on notional doses and the interpolation of values nearby the detection limits are given. (HP) [de

  15. In Pursuit of the Secret Shopper: Effective New Strategies for Finding and Engaging Prospective Students. Noel-Levitz White Paper

    Science.gov (United States)

    Noel-Levitz, Inc, 2010

    2010-01-01

    Today, prospective students in ever greater numbers are secretly exploring colleges online on their own terms, using official and unofficial sources, without completing a college's response form. Many are withholding college entrance exam scores from colleges they might be interested in and remaining unknown to their institutions of choice until…

  16. 7 CFR 54.1018 - Form of official identification and approval for use.

    Science.gov (United States)

    2010-01-01

    ...) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS..., Processing, and Packaging of Livestock and Poultry Products § 54.1018 Form of official identification and...

  17. 75 FR 12254 - Official Trail Marker for the Ala Kahakai National Historic Trail

    Science.gov (United States)

    2010-03-15

    ... comprehensive management and use Plan. It first came into public use in 2009. The National Park Service official... or in any other manner makes or executes any engraving, photograph or print, or impression in the...

  18. 43 CFR 20.201 - Ethics officials.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Ethics officials. 20.201 Section 20.201... Department Ethics Program § 20.201 Ethics officials. (a) Designated Agency Ethics Official refers to the official designated under 5 CFR 2638.201 to coordinate and manage the Department's ethics program. (b) The...

  19. 30 CFR 1.1 - Official emblem.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Official emblem. 1.1 Section 1.1 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR OFFICIAL EMBLEM AND OMB CONTROL NUMBERS... OFFICIAL EMBLEM § 1.1 Official emblem. The following emblem is established and shall be used as the...

  20. Vision in high-level football officials.

    Directory of Open Access Journals (Sweden)

    António Manuel Gonçalves Baptista

    Full Text Available Officiating in football depends, at least to some extent, upon adequate visual function. However, there is no vision standard for football officiating and the nature of the relationship between officiating performance and level of vision is unknown. As a first step in characterising this relationship, we report on the clinically-measured vision and on the perceived level of vision in elite-level, Portuguese football officials. Seventy-one referees (R and assistant referees (AR participated in the study, representing 92% of the total population of elite level football officials in Portugal in the 2013/2014 season. Nine of the 22 Rs (40.9% and ten of the 49 ARs (20.4% were international-level. Information about visual history was also gathered. Perceived vision was assessed using the preference-values-assigned-to-global-visual-status (PVVS and the Quality-of-Vision (QoV questionnaire. Standard clinical vision measures (including visual acuity, contrast sensitivity and stereopsis were gathered in a subset (n = 44, 62% of the participants. Data were analysed according to the type (R/AR and level (international/national of official, and Bonferroni corrections were applied to reduce the risk of type I errors. Adopting criterion for statistical significance of p<0.01, PVVS scores did not differ between R and AR (p = 0.88, or between national- and international-level officials (p = 0.66. Similarly, QoV scores did not differ between R and AR in frequency (p = 0.50, severity (p = 0.71 or bothersomeness (p = 0.81 of symptoms, or between international-level vs national-level officials for frequency (p = 0.03 or bothersomeness (p = 0.07 of symptoms. However, international-level officials reported less severe symptoms than their national-level counterparts (p<0.01. Overall, 18.3% of officials had either never had an eye examination or if they had, it was more than 3 years previously. Regarding refractive correction, 4.2% had undergone refractive surgery and

  1. Vision in high-level football officials.

    Science.gov (United States)

    Baptista, António Manuel Gonçalves; Serra, Pedro M; McAlinden, Colm; Barrett, Brendan T

    2017-01-01

    Officiating in football depends, at least to some extent, upon adequate visual function. However, there is no vision standard for football officiating and the nature of the relationship between officiating performance and level of vision is unknown. As a first step in characterising this relationship, we report on the clinically-measured vision and on the perceived level of vision in elite-level, Portuguese football officials. Seventy-one referees (R) and assistant referees (AR) participated in the study, representing 92% of the total population of elite level football officials in Portugal in the 2013/2014 season. Nine of the 22 Rs (40.9%) and ten of the 49 ARs (20.4%) were international-level. Information about visual history was also gathered. Perceived vision was assessed using the preference-values-assigned-to-global-visual-status (PVVS) and the Quality-of-Vision (QoV) questionnaire. Standard clinical vision measures (including visual acuity, contrast sensitivity and stereopsis) were gathered in a subset (n = 44, 62%) of the participants. Data were analysed according to the type (R/AR) and level (international/national) of official, and Bonferroni corrections were applied to reduce the risk of type I errors. Adopting criterion for statistical significance of pfootball officials were similar to published normative values for young, adult populations and similar between R and AR. Clinically-measured vision did not differ according to officiating level. Visual acuity measured with and without a pinhole disc indicated that around one quarter of participants may be capable of better vision when officiating, as evidenced by better acuity (≥1 line of letters) using the pinhole. Amongst the clinical visual tests we used, we did not find evidence for above-average performance in elite-level football officials. Although the impact of uncorrected mild to moderate refractive error upon officiating performance is unknown, with a greater uptake of eye examinations, visual

  2. Secrets to effective imaging services marketing.

    Science.gov (United States)

    Leepson, Evan

    2005-01-01

    Marketing outpatient diagnostic imaging services is similar to marketing professional services. However, the definition of marketing outpatient diagnostic imaging goes far beyond textbook and traditional meanings of marketing. There are 5 major trends that are forcing hospitals to market their diagnostic imaging services: demographics, competition, non-radiologist expansion, self-protective practice, and evolving technologies. Before thinking about identifying whom to target to develop a strategic relationship, it is necessary to get a sense of what is going on in the local area in terms of demographic trends. Much of this information can be obtained from the hospital's planning department. Local and state health planning organizations have some of the data and information. It is most critical for imaging departments to manage strategic relationships because they do not have direct access to patients. The department is solely dependent on cultivating relationships if it is to thrive. Diagnostic imaging centers have more freedom than hospitals when considering with whom to develop relationships. There are 5 essential components to any diagnostic imaging services marketing plan: be on top of referral patterns; brag about the organization's service; know the customer; keep communication channels open; and understand that marketing is a family affair. Successful diagnostic imaging marketing is key to an organization's long-term health. Developing and implementing a comprehensive, targeted, and sustained plan is crucial.

  3. The Chernobyl classified material. Secret documents from the Kremlin

    International Nuclear Information System (INIS)

    Jaroshinskaja, A.

    1994-01-01

    The author gives an account of the often related history of the Chernobyl catastrophe from the viewpoint of the local residents. She puts on record the names of those who allowed millions of people to be hit by the disaster uninformed, unwarned and unprotected. She names journalists, local politicians, party officials and scientists, until she finally arrives at the top of the Soviet body politic. - Part two of the book documents 40 secret minutes from the archives of the Kremlin. A bold stroke how the author succeeded in laying hands on these unique documents. They demonstrate how the web of lies surrounding Chernobyl was systematically woven from the first day, thread by thread. (orig./HP) [de

  4. 5 CFR 9701.523 - Official time.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Official time. 9701.523 Section 9701.523... MANAGEMENT SYSTEM Labor-Management Relations § 9701.523 Official time. (a) Any employee representing an... authorized official time for such purposes, including attendance at impasse proceedings, during the time the...

  5. Open Secrets

    OpenAIRE

    Madison, Michael

    2017-01-01

    The law of trade secrets is often conceptualized in bilateral terms, as creating and enforcing rights between trade secret owners, on the one hand, and misappropriators on the other hand. This paper, a chapter in a forthcoming collection on the law of trade secrets, argues that trade secrets and the law that guards them can serve structural and insitutional roles as well. Somewhat surprisingly, given the law’s focus on secrecy, among the institutional products of trade secrets law are commons...

  6. Taking a Page from Retail: Secret Shopping for Academic Libraries

    Directory of Open Access Journals (Sweden)

    Kathryn Crowe

    2016-03-01

    Full Text Available Objective – The University Libraries at the University of North Carolina at Greensboro (UNCG sought to gain feedback on the customer service experience beyond satisfaction surveys. After reviewing a variety of methods, it was determined to conduct a mystery or secret shopper exercise, a standard practice in the retail and hospitality world. Methods – Two mystery shopper assessments were conducted in 2010 and 2012. Students were recruited from a Hospitality Management class to serve as the secret shoppers. “Shoppers” completed a rating sheet for each encounter based on customer service values established by the Libraries. Data was analyzed and presented to staff. Results - Initial findings were generally quite positive but indicated that we could improve “going the extra mile” and “confirming satisfaction.” As a result, we developed training sessions for public services staff which were delivered during summer 2011. A LibGuide that included training videos was created for public services student employees who were required to view the videos and provide comments. In addition, we developed more specific public service standards for procedures such as answering the telephone, confirming satisfaction, and referring patrons to other offices. The Secret Shopper assessment was administered again in spring 2012 to see if scores improved. The results in the second study indicated improvement. Conclusions - The mystery shopper exercises provided the UNCG University Libraries with the opportunity to examine our services and customer service goals more closely. Conducting the mystery shopper study identified several areas to address. We realized we needed more clearly defined standards for staff to follow. We saw that we needed to discuss what “going the extra mile” means to us as an organization. We also needed to develop a scalable training method for student employees.

  7. Comparison measurements of the official individual dosimetry systems in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Boehm, J.

    1988-01-01

    At present, about 220,000 radiation workers are subject to individual monitoring of external radiation in the Federal Republic of Germany in accordance with the X-Ray Ordinance and the Radiation Protection Ordinance and the Radiation Protection Ordinance. Each radiation worker must wear at least one individual dosemeter provided by one of the five officially authorized dosemeter services. Requirements for these dosemeter services with respect to technical equipment and personnel are published in the form of a national directive. The five dosemeter services must participate in the comparison measurements for photon radiation with the official dosemeters issued by them. The comparison measurements are organized at least once a year by the Physicalisch-Technische Bundesanstalt (PTB) in agreement with the Federal Minister of Economics. Film dosemeters evaluated with a filter analysis procedure are most frequently used (96.% of all evaluations in 1984) to monitor the whole body exposure to photon radiation. Glass dosemeters play a minor role (0.5%). They are issued by only two officially authorized dosemeter services and are approved for measurements of photons with energies above 45 keV. According to the national directive, thermoluminescence dosemeters may be used only for partial body dosimetry of photon and beta radiation (2.8%). Nuclear track emulsion films are distributed to measure neutrons of energies above 0.5 MeV. A thermoluminescence albedo dosemeter for the measurement of less energetic neutrons is being introduced. The dosimetry systems involved in the comparison measurements and the operational radiation protection monitoring system of the Federal Republic of Germany are described elsewhere. The objective of this work is to describe the performance of the comparison measurements and to give some results obtained from 1979 to 1984

  8. Official Study Guide for the Certified Park and Recreation Professional. Fourth Edition

    Science.gov (United States)

    Mulvaney, Michael A.; Hurd, Amy R.

    2013-01-01

    The "Official Study Guide for the CPRP Examination" provides up-to-date information in this new edition to assist the park and recreation professional in preparing for the CPRP examination. The study guide serves as an excellent source of information for any individual who works directly or indirectly in the field of park and recreation services.

  9. Official Apologies

    DEFF Research Database (Denmark)

    Villadsen, Lisa Storm

    as strategic maneuvers regarding influence and power and as a form of political discourse chiefly concerned with reframing or recuperating particular values and norms pertinent to a community’s self-understanding. “Collective Apologies and Reconstituting Citizenship” Jason A. Edwards, Bridgewater State...... these apologies are not only how they work rhetorically, but also how they reconfigure and reconstitute citizenship domestically and internationally. For example, an official apology may allow a group of people to finally feel like they can take their place as full citizens of a particular nation-state or part...... of Social Affairs’ Reasons for not Apologizing” Lisa S. Villadsen, University of Copenhagen While official apologies issued by governments and other state representatives are more and more common in many countries, the same is not true for Denmark. A case in point is a recent case about mistreatment...

  10. Official News relating to CERN Safety Rules

    CERN Multimedia

    HSE Unit

    2015-01-01

    The CERN Safety Rules listed below have been published on the official CERN Safety Rules website (see here).   Safety Regulation SR-WS Works and services: this SR-WS (version 1) will cancel and replace the corresponding provisions of Safety Instruction IS50 “Safety Coordination on CERN Worksites”. General Safety Instruction GSI-WS-1 Safety coordination for works and services: this GSI-WS-1 (version 1) will cancel and replace the corresponding provisions of Safety Instruction IS39 “Notice of Start of Works (AOC)” and of Safety Instruction IS50 “Safety Coordination on CERN Worksites” ​Specific Safety Instruction SSI-WS-1-1 Safety coordinator for category 1 operations: this SSI-WS-1-4 (version 1) will cancel and replace the corresponding provisions of Safety Instruction IS50 “Safety Coordination on CERN Worksites”.​ ​ In order to limit the impact on the end-of-year technical st...

  11. Lessons from Early Medicaid Expansions Under Health Reform: Interviews with Medicaid Officials

    Science.gov (United States)

    Sommers, Benjamin D; Arntson, Emily; Kenney, Genevieve M; Epstein, Arnold M

    2013-01-01

    Background The Affordable Care Act (ACA) dramatically expands Medicaid in 2014 in participating states. Meanwhile, six states have already expanded Medicaid since 2010 to some or all of the low-income adults targeted under health reform. We undertook an in-depth exploration of these six “early-expander” states—California, Connecticut, the District of Columbia, Minnesota, New Jersey, and Washington—through interviews with high-ranking Medicaid officials. Methods We conducted semi-structured interviews with 11 high-ranking Medicaid officials in six states and analyzed the interviews using qualitative methods. Interviews explored enrollment outreach, stakeholder involvement, impact on beneficiaries, utilization and costs, implementation challenges, and potential lessons for 2014. Two investigators independently analyzed interview transcripts and iteratively refined the codebook until reaching consensus. Results We identified several themes. First, these expansions built upon pre-existing state-funded insurance programs for the poor. Second, predictions about costs and enrollment were challenging, indicating the uncertainty in projections for 2014. Other themes included greater than anticipated need for behavioral health services in the expansion population, administrative challenges of expansions, and persistent barriers to enrollment and access after expanding eligibility—though officials overall felt the expansions increased access for beneficiaries. Finally, political context—support or opposition from stakeholders and voters—plays a critical role in shaping the success of Medicaid expansions. Conclusions Early Medicaid expansions under the ACA offer important lessons to federal and state policymakers as the 2014 expansions approach. While the context of each state’s expansion is unique, key shared experiences were significant implementation challenges and opportunities for expanding access to needed services. PMID:24834369

  12. 31 CFR Appendix D to Subpart C of... - United States Secret Service

    Science.gov (United States)

    2010-07-01

    ... extensions of time on appeal, the officers with whom “Statements of Disagreement may be filed, the officer... person will be required to exhibit acceptable identifying documents such as employee identification... disagreement. “Statements of Disagreements” under 31 CFR 1.27 (e)(4)(i) shall be filed with the official...

  13. 75 FR 24434 - Federal Travel Regulation (FTR); Transportation in Conjunction With Official Travel and Relocation

    Science.gov (United States)

    2010-05-05

    ...-0010, sequence 1] RIN 3090-AJ02 Federal Travel Regulation (FTR); Transportation in Conjunction With Official Travel and Relocation AGENCY: Office of Governmentwide Policy, General Services Administration (GSA). ACTION: Final rule. SUMMARY: This final rule amends the Federal Travel Regulation (FTR), by...

  14. On Converting Secret Sharing Scheme to Visual Secret Sharing Scheme

    Directory of Open Access Journals (Sweden)

    Wang Daoshun

    2010-01-01

    Full Text Available Abstract Traditional Secret Sharing (SS schemes reconstruct secret exactly the same as the original one but involve complex computation. Visual Secret Sharing (VSS schemes decode the secret without computation, but each share is m times as big as the original and the quality of the reconstructed secret image is reduced. Probabilistic visual secret sharing (Prob.VSS schemes for a binary image use only one subpixel to share the secret image; however the probability of white pixels in a white area is higher than that in a black area in the reconstructed secret image. SS schemes, VSS schemes, and Prob. VSS schemes have various construction methods and advantages. This paper first presents an approach to convert (transform a -SS scheme to a -VSS scheme for greyscale images. The generation of the shadow images (shares is based on Boolean XOR operation. The secret image can be reconstructed directly by performing Boolean OR operation, as in most conventional VSS schemes. Its pixel expansion is significantly smaller than that of VSS schemes. The quality of the reconstructed images, measured by average contrast, is the same as VSS schemes. Then a novel matrix-concatenation approach is used to extend the greyscale -SS scheme to a more general case of greyscale -VSS scheme.

  15. Authentication Without Secrets

    Energy Technology Data Exchange (ETDEWEB)

    Pierson, Lyndon G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Robertson, Perry J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-11-01

    This work examines a new approach to authentication, which is the most fundamental security primitive that underpins all cyber security protections. Current Internet authentication techniques require the protection of one or more secret keys along with the integrity protection of the algorithms/computations designed to prove possession of the secret without actually revealing it. Protecting a secret requires physical barriers or encryption with yet another secret key. The reason to strive for "Authentication without Secret Keys" is that protecting secrets (even small ones only kept in a small corner of a component or device) is much harder than protecting the integrity of information that is not secret. Promising methods are examined for authentication of components, data, programs, network transactions, and/or individuals. The successful development of authentication without secret keys will enable far more tractable system security engineering for high exposure, high consequence systems by eliminating the need for brittle protection mechanisms to protect secret keys (such as are now protected in smart cards, etc.). This paper is a re-release of SAND2009-7032 with new figures numerous edits.

  16. 31 CFR 0.105 - Deputy Ethics Official.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Deputy Ethics Official. 0.105 Section... EMPLOYEE RULES OF CONDUCT General Provisions Responsibilities § 0.105 Deputy Ethics Official. The Chief Counsel or Legal Counsel for a bureau, or a designee, is the Deputy Ethics Official for that bureau. The...

  17. Secret Shopping as User Experience Assessment Tool

    Science.gov (United States)

    Boyce, Crystal M.

    2015-01-01

    Secret shopping is a form of unobtrusive evaluation that can be accomplished with minimal effort, but still produce rich results. With as few as 11 shoppers, the author was able to identify trends in user satisfaction with services provided across two entry-level desks at Illinois Wesleyan University's The Ames Library. The focus of this secret…

  18. 9 CFR 590.30 - At official plants.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false At official plants. 590.30 Section 590... Authorities § 590.30 At official plants. (a) Requirements within the scope of the Act with respect to premises, facilities, and operations of any official plant which are in addition to or different than those made under...

  19. 13 CFR 101.105 - Who may use SBA's official seal and for what purpose?

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Who may use SBA's official seal and for what purpose? 101.105 Section 101.105 Business Credit and Assistance SMALL BUSINESS... be used in any manner which implies SBA endorsement of commercial products or services or of the user...

  20. Forensic examination of ink by high-performance thin layer chromatography--the United States Secret Service Digital Ink Library.

    Science.gov (United States)

    Neumann, Cedric; Ramotowski, Robert; Genessay, Thibault

    2011-05-13

    Forensic examinations of ink have been performed since the beginning of the 20th century. Since the 1960s, the International Ink Library, maintained by the United States Secret Service, has supported those analyses. Until 2009, the search and identification of inks were essentially performed manually. This paper describes the results of a project designed to improve ink samples' analytical and search processes. The project focused on the development of improved standardization procedures to ensure the best possible reproducibility between analyses run on different HPTLC plates. The successful implementation of this new calibration method enabled the development of mathematical algorithms and of a software package to complement the existing ink library. Copyright © 2010 Elsevier B.V. All rights reserved.

  1. [Big data in official statistics].

    Science.gov (United States)

    Zwick, Markus

    2015-08-01

    The concept of "big data" stands to change the face of official statistics over the coming years, having an impact on almost all aspects of data production. The tasks of future statisticians will not necessarily be to produce new data, but rather to identify and make use of existing data to adequately describe social and economic phenomena. Until big data can be used correctly in official statistics, a lot of questions need to be answered and problems solved: the quality of data, data protection, privacy, and the sustainable availability are some of the more pressing issues to be addressed. The essential skills of official statisticians will undoubtedly change, and this implies a number of challenges to be faced by statistical education systems, in universities, and inside the statistical offices. The national statistical offices of the European Union have concluded a concrete strategy for exploring the possibilities of big data for official statistics, by means of the Big Data Roadmap and Action Plan 1.0. This is an important first step and will have a significant influence on implementing the concept of big data inside the statistical offices of Germany.

  2. EDUCATIONAL LEVEL OF OFFICIALS OF NOBLE BIRTH IN SECOND HALF OF XIX - EARLY XX CENTURIES (BASED ON MATERIALS OF THE RYAZAN PROVINCE

    Directory of Open Access Journals (Sweden)

    Наталья Викторовна Власова

    2016-12-01

    Full Text Available The article is devoted to the problems of the Russian provincial officialdom of the second half of the 19th - early 20th centuries. It analyzes the educational level of the officials of noble birth and shows the number of the officials with higher, secondary, elementary and home education. Attention is drawn to the changes in the training of the officials by the early 20th century. The paper is based on the archival materials (service records foundinthe State Archives of the Ryazan region. The analysis of the sources shows that about 15% of the officials studied in the institutions of higher education, 31% got secondary education, 29% - elementary education. About 19% had home education. And only about 21% of the officials had systematic (that is finished higher and secondary education. The author concludes that in comparison with early 19th century the educational level of the officials had an upward tendency but on the whole it continued to be low.

  3. Financing and organisation of veterinary services.

    Science.gov (United States)

    Gallacher, M; Barcos, L

    2012-08-01

    This paper analyses the different ways of financing official Veterinary Services (VS) and the effects of these choices on the performance of such Services. The links between governance, organisational effectiveness and financing arrangements are seen as particularly important. The paper comments on some of the advantages and disadvantages of financing VS with service fees, as compared to budget transfers from general government revenues. Evidence is presented on the considerable heterogeneity in the size of VS and on the impact of this heterogeneity on organisation and financing. The paper concludes with a stylised case study, which emphasises the importance of collaboration and the division of labour between the official and the private sector of the veterinary profession.

  4. Logistics Services Communication

    CERN Multimedia

    2006-01-01

    Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorisedto have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your understanding. Logistics Services - FI Department - 79947

  5. Logistics Services Communication

    CERN Document Server

    2006-01-01

    Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorised to have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your understanding. Logistics Services - FI Department - 79947

  6. 7 CFR 37.10 - Official assessment.

    Science.gov (United States)

    2010-01-01

    ... ASSESS ORGANIC CERTIFYING AGENCIES § 37.10 Official assessment. Official assessment of an applicant's certification program shall be granted upon successful completion of a two-step review process, as provided for... completion of an adequacy audit by the auditors. (b) Program assessment. Assessment of a certification...

  7. 12 CFR 328.3 - Official advertising statement requirements.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Official advertising statement requirements... OF GENERAL POLICY ADVERTISEMENT OF MEMBERSHIP § 328.3 Official advertising statement requirements. (a... medium, that is designed to attract public attention or patronage to a product or business. (b) Official...

  8. 13 CFR 105.403 - Designated Agency Ethics Officials.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Designated Agency Ethics Officials... Agency Ethics Officials. The Designated Agency Ethics Official and Alternates administer the program for... advice and counsel regarding matters relating to the Ethics in Government Act of 1978 and its...

  9. 38 CFR 0.735-1 - Agency ethics officials.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Agency ethics officials... STANDARDS OF ETHICAL CONDUCT AND RELATED RESPONSIBILITIES General Provisions § 0.735-1 Agency ethics officials. (a) Designated Agency Ethics Official (DAEO). The Assistant General Counsel (023) is the...

  10. 9 CFR 55.8 - Official CWD tests and approval of laboratories to conduct official CWD tests.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Official CWD tests and approval of laboratories to conduct official CWD tests. 55.8 Section 55.8 Animals and Animal Products ANIMAL AND PLANT... on live or dead animals, and will base the approval or disapproval of a test on the evaluation by...

  11. LcrG secretion is not required for blocking of Yops secretion in Yersinia pestis

    Directory of Open Access Journals (Sweden)

    Matson Jyl S

    2008-02-01

    Full Text Available Abstract Background LcrG, a negative regulator of the Yersinia type III secretion apparatus has been shown to be primarily a cytoplasmic protein, but is secreted at least in Y. pestis. LcrG secretion has not been functionally analyzed and the relevance of LcrG secretion on LcrG function is unknown. Results An LcrG-GAL4AD chimera, originally constructed for two-hybrid analyses to analyze LcrG protein interactions, appeared to be not secreted but the LcrG-GAL4AD chimera retained the ability to regulate Yops secretion. This result led to further investigation to determine the significance of LcrG secretion on LcrG function. Additional analyses including deletion and substitution mutations of amino acids 2–6 in the N-terminus of LcrG were constructed to analyze LcrG secretion and LcrG's ability to control secretion. Some changes to the N-terminus of LcrG were found to not affect LcrG's secretion or LcrG's secretion-controlling activity. However, substitution of poly-isoleucine in the N-terminus of LcrG did eliminate LcrG secretion but did not affect LcrG's secretion controlling activity. Conclusion These results indicate that secretion of LcrG, while observable and T3SS mediated, is not relevant for LcrG's ability to control secretion.

  12. Criminal Sanctions Against Official Corruption and other Offences Against Official Duty Offenders in Kosovo for the Period 2008-2015

    Directory of Open Access Journals (Sweden)

    Flutura Tahiraj

    2017-08-01

    Full Text Available The need to fight corruption, with the focus on official corruption in Kosovo continues to be addressed by both national and international reports. The objective of this paper is to find out the number of the cases and analyse the sactions against official corruption and other offences against official duty delivered by Municipality Courts in Kosovo during the period 2008-2015 with the aim to assess the developments during a period of eight years since most of the other researches are focused on annual performance of the courts. All data presented in this article are taken from the Kosovo Statistical Office and include statistical information on the types and frequency of criminal sanctions to perpetrators of the official corruption and other offences against official duty. Case study is also applied to analyse some court judgments. The study shows there is a slight incresase of the number of convicted perpetrators over years, the number of corruption cases addressed by the courts remained very limited, followed by low sentences or even prescription of cases. The findings will add additional scientific insights to the existing knowledge about preventing and fighting official corruption and it can be useful for scholars, policy makers and practitioners in Kosovo.

  13. Tamper-proof secret image-sharing scheme for identifying cheated secret keys and shared images

    Science.gov (United States)

    Chen, Chien-Chang; Liu, Chong-An

    2013-01-01

    A (t,n) secret image-sharing scheme shares a secret image to n participants, and the t users recover the image. During the recovery procedure of a conventional secret image-sharing scheme, cheaters may use counterfeit secret keys or modified shared images to cheat other users' secret keys and shared images. A cheated secret key or shared image leads to an incorrect secret image. Unfortunately, the cheater cannot be identified. We present an exponent and modulus-based scheme to provide a tamper-proof secret image-sharing scheme for identifying cheaters on secret keys or shared images. The proposed scheme allows users to securely select their secret key. This assignment can be performed over networks. Modulus results of each shared image is calculated to recognize cheaters of a shared image. Experimental results indicate that the proposed scheme is excellent at identifying cheated secret keys and shared images.

  14. 9 CFR 590.128 - Holiday inspection service.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Holiday inspection service. 590.128... of Service § 590.128 Holiday inspection service. (a) When an official plant requires inspection service on a holiday or a day designated in lieu of a holiday, such service is considered holiday work...

  15. 22 CFR 41.23 - Accredited officials in transit.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Accredited officials in transit. 41.23 Section... transit. An accredited official of a foreign government intending to proceed in immediate and continuous transit through the United States on official business for that government is entitled to the benefits of...

  16. Wrapped up in Covers: Preschoolers' Secrets and Secret Hiding Places

    Science.gov (United States)

    Corson, Kimberly; Colwell, Malinda J.; Bell, Nancy J.; Trejos-Castillo, Elizabeth

    2014-01-01

    In this qualitative study, interviews about children's secret hiding places were conducted with 3-5-year-olds (n?=?17) in a university sponsored preschool programme using art narratives. Since prior studies indicate that children understand the concept of a secret as early as five and that they associate secrets with hiding places, the purpose of…

  17. 78 FR 15123 - Financial Management Service; Proposed Collection of Information: Accountable Official...

    Science.gov (United States)

    2013-03-08

    ... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of...) Program AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management Service, as part of its continuing effort to reduce paperwork...

  18. Balancing Professional Standards and Political Discretion in Selecting Top Officials in Slovenia

    Directory of Open Access Journals (Sweden)

    Polonca KOVAČ

    2013-10-01

    Full Text Available One of the key drivers of modern and efficient public administration under the good governance doctrine is an efficient top officials’ selection system. A targeted selection and recruitment system is a prerequisite for the whole administration to act in compliance with the political priorities of the government. However, civil servants and top officials alike must put professional competencies above political loyalty. Therefore, a new system was introduced in Slovenia following the 2003 Civil Servants Act, aimed at ensuring professionalism against (overpoliticization of public administration. A research carried out in 2012 among candidates and selected top officials and ministers, as their political superiors, revealed an overall efficiency of the Slovenian selection scheme in the sense of restricted over-politicization and increased professionalism. Its outcomes lead to the conclusion that the selection system in Slovenia, owing to its two-phase professional and political selection, is most adequate in terms of both regulation and practice since it takes into account the twofold role of top officials and civil service or public administration as a whole (first, as a force providing professional solutions by ensuring legality and efficient resource management, and second, as the closest collaborators of the political leadership implementing government policies.

  19. 42 CFR 405.1834 - CMS reviewing official procedure.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false CMS reviewing official procedure. 405.1834 Section... Determinations and Appeals § 405.1834 CMS reviewing official procedure. (a) Scope. A provider that is a party to... Administrator by a designated CMS reviewing official who considers whether the decision of the intermediary...

  20. The Best kept Secrets In Government.

    Science.gov (United States)

    1996-09-01

    external events that could disrupt energy supplies and services. • Science and Technology. We use the unique resources of the Department’s laboratories...1996. There is no doubt that access to and 96 Appendix A use of the Internet will be a big factor enabling GSA employees to compete in the coming...workers. 113 The Best Kept Secrets In Government • Sweatshops are under attack. More than 50 manufacturing firms across the country have com

  1. 7 CFR 1951.220 - General servicing actions.

    Science.gov (United States)

    2010-01-01

    ... relatively large portion of the total value of the security property. The approval official will require a... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) SERVICING AND COLLECTIONS Servicing of Community and Direct Business...

  2. 39 CFR 221.7 - Postal Service emblem.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Postal Service emblem. 221.7 Section 221.7 Postal... Service emblem. The Postal Service emblem, which is identical with the seal, is registered as a trademark and service mark by the U.S. Patent Office. Except for the emblem on official stationery, the emblem...

  3. Salmonella-secreted Virulence Factors

    Energy Technology Data Exchange (ETDEWEB)

    Heffron, Fred; Niemann, George; Yoon, Hyunjin; Kidwai, Afshan S.; Brown, Roslyn N.; McDermott, Jason E.; Smith, Richard D.; Adkins, Joshua N.

    2011-05-01

    In this short review we discuss secreted virulence factors of Salmonella, which directly affect Salmonella interaction with its host. Salmonella secretes protein to subvert host defenses but also, as discussed, to reduce virulence thereby permitting the bacteria to persist longer and more successfully disperse. The type III secretion system (TTSS) is the best known and well studied of the mechanisms that enable secretion from the bacterial cytoplasm to the host cell cytoplasm. Other secretion systems include outer membrane vesicles, which are present in all Gram-negative bacteria examined to date, two-partner secretion, and type VI secretion will also be addressed. Excellent reviews of Salmonella secreted effectors have focused on themes such as actin rearrangements, vesicular trafficking, ubiquitination, and the activities of the virulence factors themselves. This short review is based on S. Typhimurium infection of mice because it is a model of typhoid like disease in humans. We have organized effectors in terms of events that happen during the infection cycle and how secreted effectors may be involved.

  4. Changing Occupational Roles in Audit Society—The Case of Swedish Student Aid Officials

    Directory of Open Access Journals (Sweden)

    Anders Bruhn

    2015-03-01

    Full Text Available This article is about occupational change concerning a non-professional group of Street Level Bureaucrats—student aid officials at the Swedish Board for Study Support (SBSS. The aim is to describe and analyze changes in their occupational role—their discretional space and working conditions under the impact of changed ways to manage public service organizations and new information and communication technology. The SBSS is the sole administrator of student financial aid in Sweden. Its officials investigate and take decisions about students’ applications and repayment of loans. This work includes interacting with clients via telephone and computer. These officials have to have a certain amount of discretion to interpret and apply rules and regulations on specific circumstances in individual cases. How are their working conditions affected by organizational and policy changes in the authority? How is their ability to exercise influence and control over their own work performance affected? The analysis highlights how officials suffer from decreased discretion and an increasing routinization in their work. This is a result of a regulatory framework continuously growing in detail together with increasing management control based on new information and communication technology. What remains of discretion is a kind of ‘task’ discretion, the ability to do minor technical manipulations of rules in individual cases. Even today’s top management seems critical of this development. Besides further automatization and reduction of staff an ongoing process of organizational change is therefore also aiming to develop officials’ competence and working conditions toward what may be seen as organizational professionalism, a development of specific occupational skills and a discretion adjusted and subordinated to managerial means and ends. The analysis rests on data from a research project (2011 to 2014 about Institutional Talk. Data sources are

  5. Meaningful Share Generation for Increased Number of Secrets in Visual Secret-Sharing Scheme

    Directory of Open Access Journals (Sweden)

    Mustafa Ulutas

    2010-01-01

    Full Text Available This paper presents a new scheme for hiding two halftone secret images into two meaningful shares created from halftone cover images. Meaningful shares are more desirable than noise-like (meaningless shares in Visual Secret Sharing because they look natural and do not attract eavesdroppers' attention. Previous works in the field focus on either increasing number of secrets or creating meaningful shares for one secret image. The method outlined in this paper both increases the number of secrets and creates meaningful shares at the same time. While the contrast ratio of shares is equal to that of Extended Visual Cryptography, two secrets are encoded into two shares as opposed to one secret in the Extended Visual Cryptography. Any two natural-looking images can be used as cover unlike the Halftone Visual Cryptography method where one cover should be the negative of the other cover image and can only encode one secret. Effectiveness of the proposed method is verified by an experiment.

  6. 75 FR 1541 - Purchasing of Property and Services

    Science.gov (United States)

    2010-01-12

    ... persons; and to develop further the basis for the Postal Service's purchasing decisions and the... decision process. The SDR Official will promptly provide a copy of a disagreement to the contracting... POSTAL SERVICE 39 CFR Part 601 Purchasing of Property and Services AGENCY: Postal Service TM...

  7. 36 CFR 907.4 - Designation of responsible Corporation official.

    Science.gov (United States)

    2010-07-01

    ... Corporation official. 907.4 Section 907.4 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION ENVIRONMENTAL QUALITY § 907.4 Designation of responsible Corporation official. The Development Director is the Corporation official responsible for implementation and operation of the Corporation's...

  8. Official Centre Hospitality

    International Development Research Centre (IDRC) Digital Library (Canada)

    Sylvain Dufour

    Approved by the Management Executive Committee. - 1 -. Version 3.1.0 effective 2017-06-28. Official Centre Hospitality. 1. Objective. 2. Application. 3. Definitions. 4. Roles and Responsibilities. 5. Authorization. 6. Consultants and Contractors. 7. Reimbursement. 1. Objective. To define the circumstances under which ...

  9. 22 CFR 510.1 - Service of process.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Service of process. 510.1 Section 510.1 Foreign Relations BROADCASTING BOARD OF GOVERNORS SERVICE OF PROCESS § 510.1 Service of process. (a) The General... accepting service of process for an employee in his/her official capacity, the General Counsel or his/her...

  10. Determination of the knowledge level, attitudes, and behaviors of islamic religious officials toward blood donation.

    Science.gov (United States)

    Keten, Hamit Sirri; Isik, Oguz; Kus, Celal; Ersoy, Ozgur; Olmez, Soner; Yildirim, Fatis; Celik, Mustafa

    2017-12-01

    The aim of the present study was to determine knowledge level, attitudes, and behaviors of Islamic religious officials toward blood donation. This study included 334 religious officials rendering service in the province of Kahramanmaras, located in the Mediterranean region of Turkey. A questionnaire was administered to gather sociodemographic data of the participants and their knowledge levels, attitudes, and behaviors toward blood donation. The questionnaire consisted of 11 questions that yielded a total of 11 points. The religious officials in the study included 206 imams (61.7%, males) and 128 Quran course instructors (38.3%, females). Of study participants, 134 (40.1%) reported a previous experience of blood donation and 200 (59.9%) denied previous experience of blood donation. The mean knowledge score was 7.09±2.54 points for males and 6.89±2.18 points for females. Male and female participants achieved comparable scores (p=0.476). Of the participants, 291 (87.1%) agreed and nine (2.7%) disagreed with the expression, "Blood donation is permissible in Islam;" 34 (10.2%) participants had no idea. The present study revealed considerable deficiencies in knowledge about blood donation among religious officials. In addition, the rate of blood donation and willingness to donate blood were low among religious officials. Although the level of knowledge about blood donation was similar in males and females, it was an interesting finding that the blood donation rate was significantly higher in males than in females. Copyright © 2017 Elsevier Ltd. All rights reserved.

  11. Pioneering SESAME light source officially opened

    CERN Multimedia

    Caraban Gonzalez, Noemi

    2017-01-01

    Allan, Jordan, 16 May 2017. The SESAME light source was today officially opened by His Majesty King Abdullah II. An intergovernmental organization, SESAME is the first regional laboratory for the Middle East and neighbouring regions The laboratory’s official opening ushers in a new era of research covering fields ranging from medicine and biology, through materials science, physics and chemistry to healthcare, the environment, agriculture and archaeology.

  12. 5 CFR 2638.204 - Deputy ethics official.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Deputy ethics official. 2638.204 Section 2638.204 Administrative Personnel OFFICE OF GOVERNMENT ETHICS GOVERNMENT ETHICS OFFICE OF GOVERNMENT ETHICS AND EXECUTIVE AGENCY ETHICS PROGRAM RESPONSIBILITIES Designated Agency Ethics Official § 2638.204...

  13. Cholecystokinin inhibits gastrin secretion independently of paracrine somatostatin secretion in the pig

    DEFF Research Database (Denmark)

    Schmidt, P T; Hansen, L; Hilsted, L

    2004-01-01

    BACKGROUND: Cholecystokinin inhibits the secretion of gastrin from antral G cells, an effect that is speculated to be mediated by D cells secreting somatostatin. The aim of the study was to test directly whether cholecystokinin inhibition of antral gastrin secretion is mediated by somatostatin....... METHODS: The effects of CCK on gastrin and somatostatin secretion were studied in isolated vascularly perfused preparations of pig antrum before and after immunoneutralization brought about by infusion of large amounts of a high affinity monoclonal antibody against somatostatin. RESULTS: CCK infusion...... at 10(-9) M and 10(-8) M decreased gastrin output to 70.5% +/- 7.6% (n = 8) and 76.3% +/- 3.6% (n = 7) of basal output, respectively. CCK at 10(-10) M had no effect (n = 6). Somatostatin secretion was dose-dependently increased by CCK infusion and increased to 268 +/- 38.2% (n = 7) of basal secretion...

  14. 26 CFR 1.121-5 - Suspension of 5-year period for certain members of the uniformed services and Foreign Service.

    Science.gov (United States)

    2010-04-01

    ... REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED... official extended duty as a member of the Foreign Service of the United States in Brazil. In 2015 B sells... period of ownership and use during his 8-year period of service with the Foreign Service in Brazil. If B...

  15. Dynamic quantum secret sharing

    International Nuclear Information System (INIS)

    Jia, Heng-Yue; Wen, Qiao-Yan; Gao, Fei; Qin, Su-Juan; Guo, Fen-Zhuo

    2012-01-01

    In this Letter we consider quantum secret sharing (QSS) between a sender and a dynamic agent group, called dynamic quantum secret sharing (DQSS). In the DQSS, the change of the agent group is allowable during the procedure of sharing classical and quantum information. Two DQSS schemes are proposed based on a special kind of entangled state, starlike cluster states. Without redistributing all the shares, the changed agent group can reconstruct the sender's secret by their cooperation. Compared with the previous quantum secret sharing scheme, our schemes are more flexible and suitable for practical applications. -- Highlights: ► We consider quantum secret sharing between a sender and a dynamic agent group, called dynamic quantum secret sharing (DQSS). ► In the DQSS, the change of the agent group is allowable during the procedure of sharing classical and quantum information. ► Two DQSS schemes are proposed based on a special kind of entangled state, starlike cluster states. ► Without redistributing all the shares, the changed agent group can reconstruct the sender's secret by their cooperation. ► Compared with the previous quantum secret sharing scheme, our schemes are more flexible and suitable for practical applications.

  16. 14 CFR 1203.412 - Classification guides.

    Science.gov (United States)

    2010-01-01

    ... of the classification designations (i.e., Top Secret, Secret or Confidential) apply to the identified... writing by an official with original Top Secret classification authority; the identity of the official...

  17. 9 CFR 77.34 - Official tuberculosis tests.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Official tuberculosis tests. 77.34... AGRICULTURE INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS TUBERCULOSIS Captive Cervids § 77.34 Official tuberculosis tests. (a) Single cervical tuberculin (SCT) test. (1) The SCT test...

  18. Online and official price indexes: Measuring Argentina's inflation

    OpenAIRE

    Cavallo, Alberto F.

    2013-01-01

    Prices collected from online retailers can be used to construct daily price indexes that complement official statistics. This paper studies their ability to match official inflation estimates in five Latin American countries, with a focus on Argentina, where official statistics have been heavily criticized in recent years. The data were collected between October 2007 and March 2011 from the largest supermarket in each country. In Brazil, Chile, Colombia, and Venezuela, online price indexes ap...

  19. 18 CFR 3a.11 - Classification of official information.

    Science.gov (United States)

    2010-04-01

    ... classified Top Secret, Secret or Confidential, depending upon the degree of its significance to national... classification categories are defined as follows: (1) Top Secret. Top Secret refers to national security information or material which requires the highest degree of protection. The test for assigning Top Secret...

  20. 6 CFR 7.20 - Classification and declassification authority.

    Science.gov (United States)

    2010-01-01

    .... (a) Top Secret original classification authority may only be exercised by the Secretary of Homeland... up to and including Top Secret. No official who is delegated Top Secret original classification... Secret and Confidential original classification authority to other officials determined to have frequent...

  1. Announcement by the Logistics Service

    CERN Document Server

    GS Department

    2011-01-01

    Please note that CERN will dispatch or deliver only packages that relate to official orders or contracts. Individuals are not authorised to have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your co-operation. GS-IS-LS Service

  2. 45 CFR 73.735-202 - Management officials.

    Science.gov (United States)

    2010-10-01

    ...) Department Ethics Counselor. The Assistant General Counsel, Business and Administrative Law Division, shall... 45 Public Welfare 1 2010-10-01 2010-10-01 false Management officials. 73.735-202 Section 73.735... Responsibilities § 73.735-202 Management officials. (a) The Department has an obligation to enforce the...

  3. 6 CFR 13.5 - Review by the Reviewing Official.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Review by the Reviewing Official. 13.5 Section 13.5 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.5 Review by the Reviewing Official. (a) If, based on the report of the Investigating Official...

  4. 7 CFR 37.8 - Financial interest of official.

    Science.gov (United States)

    2010-01-01

    ... REGULATIONS PROGRAM TO ASSESS ORGANIC CERTIFYING AGENCIES § 37.8 Financial interest of official. No auditor or other Department official shall review any programs or documents concerning a certification program in...

  5. 32 CFR 2400.7 - Original classification authority.

    Science.gov (United States)

    2010-07-01

    ... original classification of information as Top Secret shall be exercised within OSTP only by the Director... Top Secret classification authority, and any other officials delegated in writing to have original... shall be exercised within OSTP only by officials with original Top Secret or Secret classification...

  6. Understanding Internal Accountability in Nigeria’s Routine Immunization System: Perspectives From Government Officials at the National, State, and Local Levels

    Directory of Open Access Journals (Sweden)

    Daniel J. Erchick

    2017-07-01

    Full Text Available Background Routine immunization coverage in Nigeria has remained low, and studies have identified a lack of accountability as a barrier to high performance in the immunization system. Accountability lies at the heart of various health systems strengthening efforts recently launched in Nigeria, including those related to immunization. Our aim was to understand the views of health officials on the accountability challenges hindering immunization service delivery at various levels of government. Methods A semi-structured questionnaire was used to interview immunization and primary healthcare (PHC officials from national, state, local, and health facility levels in Niger State in north central Nigeria. Individuals were selected to represent a range of roles and responsibilities in the immunization system. The questionnaire explored concepts related to internal accountability using a framework that organizes accountability into three axes based upon how they drive change in the health system. Results Respondents highlighted accountability challenges across multiple components of the immunization system, including vaccine availability, financing, logistics, human resources, and data management. A major focus was the lack of clear roles and responsibilities both within institutions and between levels of government. Delays in funding, especially at lower levels of government, disrupted service delivery. Supervision occurred less frequently than necessary, and the limited decision space of managers prevented problems from being resolved. Motivation was affected by the inability of officials to fulfill their responsibilities. Officials posited numerous suggestions to improve accountability, including clarifying roles and responsibilities, ensuring timely release of funding, and formalizing processes for supervision, problem solving, and data reporting. Conclusion Weak accountability presents a significant barrier to performance of the routine immunization

  7. Graft and Corruption Practices Among Selected Public Officials in Mindanao, Southern Philippines

    Directory of Open Access Journals (Sweden)

    Amer Husain L. Laut

    2013-08-01

    Full Text Available This study aims to examine the graft and corruption practices among selected public officials in southern Philippines. The study is qualitative in nature making use of case study method in which an in-depth analysis of primary data obtained from eight informants, four of whom are town mayors and their four incumbent municipal treasurers, is employed. The findings revealed that the mayor informants got elected through vote buying and bribery. Politics and family matters intersect as informants are supported by their families during election who used guns, gold and goons to ensure election victory. The clannish nature of the community finds expression also in the selection of relatives in municipal employment and in accessing municipal resources. The most prevalent corruption practice disclosed by the informants is amassing the internal revenue allotment (IRA for personal purposes in order to recover the huge amount of money spent during election. Other types of corruption practices also include falsification of documents, nepotism, bribery, kickbacks, and evasion of public bidding. These public officials also do not seem to perform official duties in their towns as they live outside of their municipalities. Inter-agency involvement of corruption among different government agencies in the areas studied are also uncovered. Moreover, the perceived negative effects of corruption are manifested in the poor delivery of the community’s basic social services in health, water supply, education, and security protection. Corruption also adversely affects the construction of community infrastructure facilities and the establishment of an equitable and solid economic base. The study has implications to the strict policy implementation of the provisions of the 1991 Local Government Code of the Philippines, The Anti-Graft and Corrupt Practices Act, and other pertinent laws in order to improve the transparency, integrity and accountability of public officials

  8. 32 CFR 720.20 - Service of process upon personnel.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Service of process upon personnel. 720.20... DELIVERY OF PERSONNEL; SERVICE OF PROCESS AND SUBPOENAS; PRODUCTION OF OFFICIAL RECORDS Service of Process and Subpoenas Upon Personnel § 720.20 Service of process upon personnel. (a) General. Commanding...

  9. 32 CFR 734.3 - Service of process.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Service of process. 734.3 Section 734.3 National... MILITARY AND CIVILIAN PERSONNEL FOR COLLECTION OF CHILD SUPPORT AND ALIMONY § 734.3 Service of process. (a... naval officials. Service of legal process affecting the pay of Department of the Navy personnel shall be...

  10. Constructing process views for service outsourcing

    NARCIS (Netherlands)

    Eshuis, H.; Norta, A.H.; Shin, S.Y.; Ossowski, S.

    2009-01-01

    Service outsourcing is a business paradigm in which an organization has a part of its business process performed by a service provider. The outsourced service can be specified in a public process view, which shields secret or irrelevant details from the internal business process of the provider.

  11. The service of public services performance management

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    perspectives on the potential impact of public service performance measurement offer a range of contradictory propositions. Its alleged benefits include public assurance, better functioning of supply markets for public services, and direct improvements of public services. But the literature also demonstrates...... the existence of significant concern about the actual impact, the costs and unintended consequences associated with performance measurement.  Performance measurement and management have been part of the political agenda within the public sphere since their adoption in the post-Second World War period...... of political masters and their mistresses rather than public service. Another area of concern is the cost of performance measurement. Hood & Peters (2004:278) note that performance measurement is likely to “distract middle- and upper-level officials, create massive paperwork, and produce major unintended...

  12. Note from the Goods Reception services

    CERN Multimedia

    FI Department

    2008-01-01

    Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorised to have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Goods Reception Services

  13. 48 CFR 237.104 - Personal services contracts.

    Science.gov (United States)

    2010-10-01

    ... intelligence component or counter-intelligence organization of DoD; or (iii) Directly support the mission of... travel between home or place of business and official duty station. (iii) Coordinate with the civilian... SYSTEM, DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Service Contracts...

  14. Corruption Practices Among Young Elective Public Officials (Sanggunian Kabataan In Iligan City, Southern Philippines

    Directory of Open Access Journals (Sweden)

    Sulpecia L. Ponce

    2013-08-01

    Full Text Available This study attempts to explore the involvement in graft and corruption among elective barangay youth officials in a city in Southern Philippines. Using a qualitative research design employing a case study method, 10 informants were included in this study and were selected using snowball sampling technique. The findings indicated that the informants were aware of the forms of graft and corrupt practices stipulated in the Anti-Graft and Corrupt Practices Act in the Philippines (RA 3019 and other legal documents. However, despite this, most of them admitted to have been involved in any of the follow-ing irregular acts while in public service: malversation of public funds, evasion of public bidding in the purchase of supplies and equipments, forgery, bribery, making ghost projects and payrolls, abuse of powers, among others. It was known also that corruption was caused mainly by bureaucratic dys-functions especially in the delay of budget releases and political socialization with older and corrupt barangay officials who passed on the techniques of corruption to the young leader informants. The policy implications of the study demands further strength-ening of governmental structures and processes that would ensure observance of good governance among public officials both at the barangay ( local and national levels.

  15. Official regulations and perceptual aspects of bell ringing

    Directory of Open Access Journals (Sweden)

    Kovačič Mojca

    2017-01-01

    Full Text Available Through the analytical approach of studying official and perception-related discourse on bell ringing I accentuate the complexity of aspects that the sound of church bell presents in contemporary society. I point out the misleading officially defined level of noise nuisance and reveal how, when and why bell ringing is perceived as a positive or negative part of the acoustic environment. The study argues for a holistic approach to the noise nuisance issues, still much underestimated in the official discourse, that co-create our everyday soundscape.

  16. From Quality to Information Quality in Official Statistics

    Directory of Open Access Journals (Sweden)

    Kenett Ron S.

    2016-12-01

    Full Text Available The term quality of statistical data, developed and used in official statistics and international organizations such as the International Monetary Fund (IMF and the Organisation for Economic Co-operation and Development (OECD, refers to the usefulness of summary statistics generated by producers of official statistics. Similarly, in the context of survey quality, official agencies such as Eurostat, National Center for Science and Engineering Statistics (NCSES, and Statistics Canada have created dimensions for evaluating the quality of a survey and its ability to report ‘accurate survey data’.

  17. Quantum strongly secure ramp secret sharing

    DEFF Research Database (Denmark)

    Zhang, Paul; Matsumoto, Rytaro Yamashita

    2015-01-01

    Quantum secret sharing is a scheme for encoding a quantum state (the secret) into multiple shares and distributing them among several participants. If a sufficient number of shares are put together, then the secret can be fully reconstructed. If an insufficient number of shares are put together...... however, no information about the secret can be revealed. In quantum ramp secret sharing, partial information about the secret is allowed to leak to a set of participants, called an unqualified set, that cannot fully reconstruct the secret. By allowing this, the size of a share can be drastically reduced....... This paper introduces a quantum analog of classical strong security in ramp secret sharing schemes. While the ramp secret sharing scheme still leaks partial information about the secret to unqualified sets of participants, the strong security condition ensures that qudits with critical information can...

  18. Secrets from friends and parents: longitudinal links with depression and antisocial behavior.

    Science.gov (United States)

    Laird, Robert D; Bridges, Brittanee J; Marsee, Monica A

    2013-08-01

    Keeping secrets from parents is associated with depression and antisocial behavior. The current study tested whether keeping secrets from best friends is similarly linked to maladjustment, and whether associations between secrecy and maladjustment are moderated by the quality of the friendship. Adolescents (N = 181; 51% female, 48% white, non-Hispanic, 45% African American) reported their secrecy from parents and best friends, the quality of their parent-adolescent relationships and best friendships, and their depression and antisocial behavior at ages 12 and 13. Keeping more secrets from best friends was associated with more depression, but not with more antisocial behavior, when controlling for earlier adjustment, secrecy from parents, and the quality of the friendship. For girls associations between maladjustment and secrecy were conditioned by the quality of the relationships and whether secrets were kept from parents and friends. Discussion argues for expanding the study of secrecy in adolescence beyond the parent-child dyad. Copyright © 2013 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  19. 21 CFR 1316.63 - Official transcript; index; corrections.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 9 2010-04-01 2010-04-01 false Official transcript; index; corrections. 1316.63 Section 1316.63 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE ADMINISTRATIVE FUNCTIONS, PRACTICES, AND PROCEDURES Administrative Hearings § 1316.63 Official transcript; index...

  20. Dynamic secrets in communication security

    CERN Document Server

    Xiao, Sheng; Towsley, Donald

    2013-01-01

    Dynamic secrets are constantly generated and updated from messages exchanged between two communication users. When dynamic secrets are used as a complement to existing secure communication systems, a stolen key or password can be quickly and automatically reverted to its secret status without disrupting communication. 'Dynamic Secrets in Communication Security' presents unique security properties and application studies for this technology. Password theft and key theft no longer pose serious security threats when parties frequently use dynamic secrets. This book also illustrates that a dynamic

  1. Official Union Time Tracking System

    Data.gov (United States)

    Social Security Administration — Official Union Time Tracking System captures the reporting and accounting of the representational activity for all American Federation of Government Employees (AFGE)...

  2. Ensuring services to the poor : learning from LLPMS

    International Development Research Centre (IDRC) Digital Library (Canada)

    fajardojp

    necessary steps to delivery services to ensure providing basic facilities but poverty remains central ... services, technological transfer, imparting training, input supply within reasonable ... Providing education, ensuring health facility, safe ..... a workshop organised to get feedback on the methodology of LLPMS the officials of.

  3. Mining secreted proteins that function in pepper fruit development and ripening using a yeast secretion trap (YST)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Je Min, E-mail: jemin@knu.ac.kr [Department of Plant Science, College of Agriculture and Life Sciences, Seoul National University, Seoul (Korea, Republic of); Department of Horticultural Science, Kyungpook National University, Daegu (Korea, Republic of); Lee, Sang-Jik [Biotechnology Institute, Nongwoo Bio Co, Ltd, Yeoju (Korea, Republic of); Department of Plant Biology, Cornell University, Ithaca, NY (United States); Rose, Jocelyn K.C. [Department of Plant Biology, Cornell University, Ithaca, NY (United States); Yeam, Inhwa [Department of Horticulture and Breeding, Andong National University, Andong (Korea, Republic of); Kim, Byung-Dong [Department of Plant Science, College of Agriculture and Life Sciences, Seoul National University, Seoul (Korea, Republic of)

    2014-04-18

    Highlights: • Yeast secretion trap (YST) is a valuable tool for mining secretome. • A total of 80 secreted proteins are newly identified via YST in pepper fruits. • The secreted proteins are differentially regulated during pepper development and ripening. • Transient GFP-fusion assay and in planta secretion trap can effectively validate the secretion of proteins. - Abstract: Plant cells secrete diverse sets of constitutively- and conditionally-expressed proteins under various environmental and developmental states. Secreted protein populations, or secretomes have multiple functions, including defense responses, signaling, metabolic processes, and developmental regulation. To identify genes encoding secreted proteins that function in fruit development and ripening, a yeast secretion trap (YST) screen was employed using pepper (Capsicum annuum) fruit cDNAs. The YST screen revealed 80 pepper fruit-related genes (CaPFRs) encoding secreted proteins including cell wall proteins, several of which have not been previously described. Transient GFP-fusion assay and an in planta secretion trap were used to validate the secretion of proteins encoded by selected YST clones. In addition, RNA gel blot analyses provided further insights into their expression and regulation during fruit development and ripening. Integrating our data, we conclude that the YST provides a valuable functional genomics tool for the identification of substantial numbers of novel secreted plant proteins that are associated with biological processes, including fruit development and ripening.

  4. Mining secreted proteins that function in pepper fruit development and ripening using a yeast secretion trap (YST)

    International Nuclear Information System (INIS)

    Lee, Je Min; Lee, Sang-Jik; Rose, Jocelyn K.C.; Yeam, Inhwa; Kim, Byung-Dong

    2014-01-01

    Highlights: • Yeast secretion trap (YST) is a valuable tool for mining secretome. • A total of 80 secreted proteins are newly identified via YST in pepper fruits. • The secreted proteins are differentially regulated during pepper development and ripening. • Transient GFP-fusion assay and in planta secretion trap can effectively validate the secretion of proteins. - Abstract: Plant cells secrete diverse sets of constitutively- and conditionally-expressed proteins under various environmental and developmental states. Secreted protein populations, or secretomes have multiple functions, including defense responses, signaling, metabolic processes, and developmental regulation. To identify genes encoding secreted proteins that function in fruit development and ripening, a yeast secretion trap (YST) screen was employed using pepper (Capsicum annuum) fruit cDNAs. The YST screen revealed 80 pepper fruit-related genes (CaPFRs) encoding secreted proteins including cell wall proteins, several of which have not been previously described. Transient GFP-fusion assay and an in planta secretion trap were used to validate the secretion of proteins encoded by selected YST clones. In addition, RNA gel blot analyses provided further insights into their expression and regulation during fruit development and ripening. Integrating our data, we conclude that the YST provides a valuable functional genomics tool for the identification of substantial numbers of novel secreted plant proteins that are associated with biological processes, including fruit development and ripening

  5. 37 CFR 104.12 - Acceptance of service of process.

    Science.gov (United States)

    2010-07-01

    ... OFFICE, DEPARTMENT OF COMMERCE ADMINISTRATION LEGAL PROCESSES Service of Process § 104.12 Acceptance of service of process. (a) Any summons and complaint to be served in person or by registered or certified...). (f) The Office will only accept service of process for an employee in the employee's official...

  6. 50 CFR 401.20 - Officials not to benefit.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Officials not to benefit. 401.20 Section... ADMINISTRATION, DEPARTMENT OF COMMERCE); ENDANGERED SPECIES COMMITTEE REGULATIONS SUBCHAPTER A ANADROMOUS FISHERIES CONSERVATION, DEVELOPMENT AND ENHANCEMENT § 401.20 Officials not to benefit. No Member of, or...

  7. Immunoglobins in mammary secretions

    DEFF Research Database (Denmark)

    Hurley, W L; Theil, Peter Kappel

    2013-01-01

    Immunoglobulins secreted in colostrum and milk by the lactating mammal are major factors providing immune protection to the newborn. Immunoglobulins in mammary secretions represent the cumulative immune response of the lactating animal to exposure to antigenic stimulation that occurs through...... the immunoglobulins found in mammary secretions in the context of their diversity of structure, origin, mechanisms of transfer, and function....

  8. Matroids and quantum-secret-sharing schemes

    International Nuclear Information System (INIS)

    Sarvepalli, Pradeep; Raussendorf, Robert

    2010-01-01

    A secret-sharing scheme is a cryptographic protocol to distribute a secret state in an encoded form among a group of players such that only authorized subsets of the players can reconstruct the secret. Classically, efficient secret-sharing schemes have been shown to be induced by matroids. Furthermore, access structures of such schemes can be characterized by an excluded minor relation. No such relations are known for quantum secret-sharing schemes. In this paper we take the first steps toward a matroidal characterization of quantum-secret-sharing schemes. In addition to providing a new perspective on quantum-secret-sharing schemes, this characterization has important benefits. While previous work has shown how to construct quantum-secret-sharing schemes for general access structures, these schemes are not claimed to be efficient. In this context the present results prove to be useful; they enable us to construct efficient quantum-secret-sharing schemes for many general access structures. More precisely, we show that an identically self-dual matroid that is representable over a finite field induces a pure-state quantum-secret-sharing scheme with information rate 1.

  9. Extracellular secretion of recombinant proteins

    Science.gov (United States)

    Linger, Jeffrey G.; Darzins, Aldis

    2014-07-22

    Nucleic acids encoding secretion signals, expression vectors containing the nucleic acids, and host cells containing the expression vectors are disclosed. Also disclosed are polypeptides that contain the secretion signals and methods of producing polypeptides, including methods of directing the extracellular secretion of the polypeptides. Exemplary embodiments include cellulase proteins fused to secretion signals, methods to produce and isolate these polypeptides, and methods to degrade lignocellulosic biomass.

  10. Service outsourcing with process views

    NARCIS (Netherlands)

    Eshuis, H.; Norta, A.H.; Kopp, O.; Pitkänen, E.

    2015-01-01

    Service outsourcing is a business paradigm in which an organization has a part of its business process performed by a service provider. Process views are pivotal to support this way of working. A process view shields secret or irrelevant details from a private business process, thus allowing an

  11. THE USE OF OFFICIAL LANGUAGES ACT: DIVERSITY AFFIRMED?

    Directory of Open Access Journals (Sweden)

    JL (Loot Pretorius

    2013-04-01

    Full Text Available SUMMARYA full sixteen years after the coming into force of the 1996 Constitution, Parliament responded to the constitutional obligation to regulate and monitor, by legislative and other means, the use of official languages by adopting the Use of Official Languages Act 12 of 2012. The Act represents a very limited normative appreciation of this constitutional instruction. The official language clause of the Constitution expresses a normative commitment regarding the positive affirmation of linguistic diversity, which is directly informed by and closely aligned to the core normative values of the Constitution. The Constitution’s positive evaluation of difference, including linguistic difference, inter alia, flows from the values of substantive equality, equal citizenship, dignity and proportionality. However, the way in which the Act institutionalises the promotion of inclusive linguistic diversity does not reflect an unambiguous recognition of this obligation being normatively embedded in the foundational value structure of the Constitution. The real responsibility for decisions regarding official language use is located in the policy-making competence of non-independent administrative bodies. The Act itself is devoid of instructive standards of its own to guide administrative decision-making regarding official language use. This results in the responsibility for making the most important normative choices regarding the use of official languages not being reserved for the legislative process, but entrusted to non-independent advisory administrative bodies. The nature of the Act confirms that it never was the intention of the government to be bound by legislation in this respect. This modus operandi is democratically deficient and compromises both the separation of powers and the principle of legal certainty as fundamental tenets of the rule of law.

  12. 9 CFR 350.3 - Types and availability of service.

    Science.gov (United States)

    2010-01-01

    ....3 Section 350.3 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT OF... product must be sound, wholesome and fit for human food. The service will be available only on premises... service will be available for products moved in tank cars and tank trucks from an official establishment...

  13. 41 CFR 101-39.202 - Contractor authorized services.

    Science.gov (United States)

    2010-07-01

    ... VEHICLES 39-INTERAGENCY FLEET MANAGEMENT SYSTEMS 39.2-GSA Interagency Fleet Management System Services... related GSA Interagency Fleet Management System (IFMS) services solely for official purposes. (b) To the... -leased equipment which is not controlled by a GSA IFMS fleet management center, or for authorized...

  14. 7 CFR 58.58 - Debarment of service.

    Science.gov (United States)

    2010-01-01

    ... any application for any inspection or grading service, appeal reinspection, or regrading service; (ii... “Government graded,” or terms of similar import in the labeling or advertising of any product without stating... aforesaid terms or an official stamp, label, or identification in the labeling or advertising of any product...

  15. Logistics Services Reminder

    CERN Multimedia

    Logistics Services

    2016-01-01

    Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorised to have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your understanding.

  16. Komunikasi Corporate Social Responsibility pada Official Website Perusahaan Badan Usaha Milik Negara

    Directory of Open Access Journals (Sweden)

    Nurjannah Nurjannah

    2017-05-01

    Full Text Available This study describes Corporate Social Responsibility (CSR message on official website of State Owned Enterprises (SOEs and features of official website as CSR communication medium. Quantitative content analysis is used as the method. Data were analyzed by using descriptive statistics. This study selected 55 Indonesian SOEs official website. The result shows that state-owned companies have not applied transparency of CSR communication messages on their official website. The study finds that a number of state-owned companies do not present CSR information on their official website. In general, CSR communication on the official website of state-owned companies is limited to presenting information related to government program called Partnership Program and Community Development (PKBL. The official websites of state-owned companies have not utilized potential use of the website as communication medium of CSR. State-owned companies have not fully realized the role of official website as strategic media in conveying CSR communication message.

  17. Pituitary-hormone secretion by thyrotropinomas.

    Science.gov (United States)

    Roelfsema, Ferdinand; Kok, Simon; Kok, Petra; Pereira, Alberto M; Biermasz, Nienke R; Smit, Jan W; Frolich, Marijke; Keenan, Daniel M; Veldhuis, Johannes D; Romijn, Johannes A

    2009-01-01

    Hormone secretion by somatotropinomas, corticotropinomas and prolactinomas exhibits increased pulse frequency, basal and pulsatile secretion, accompanied by greater disorderliness. Increased concentrations of growth hormone (GH) or prolactin (PRL) are observed in about 30% of thyrotropinomas leading to acromegaly or disturbed sexual functions beyond thyrotropin (TSH)-induced hyperthyroidism. Regulation of non-TSH pituitary hormones in this context is not well understood. We there therefore evaluated TSH, GH and PRL secretion in 6 patients with up-to-date analytical and mathematical tools by 24-h blood sampling at 10-min intervals in a clinical research laboratory. The profiles were analyzed with a new deconvolution method, approximate entropy, cross-approximate entropy, cross-correlation and cosinor regression. TSH burst frequency and basal and pulsatile secretion were increased in patients compared with controls. TSH secretion patterns in patients were more irregular, but the diurnal rhythm was preserved at a higher mean with a 2.5 h phase delay. Although only one patient had clinical acromegaly, GH secretion and IGF-I levels were increased in two other patients and all three had a significant cross-correlation between the GH and TSH. PRL secretion was increased in one patient, but all patients had a significant cross-correlation with TSH and showed decreased PRL regularity. Cross-ApEn synchrony between TSH and GH did not differ between patients and controls, but TSH and PRL synchrony was reduced in patients. We conclude that TSH secretion by thyrotropinomas shares many characteristics of other pituitary hormone-secreting adenomas. In addition, abnormalities in GH and PRL secretion exist ranging from decreased (joint) regularity to overt hypersecretion, although not always clinically obvious, suggesting tumoral transformation of thyrotrope lineage cells.

  18. Official Basketball Rules for Girls and Women. July 1972 - July 1973. Reprint.

    Science.gov (United States)

    American Association for Health, Physical Education, and Recreation, Washington, DC. Div. for Girls and Women's Sports.

    The official American Association for Health, Physical Education, and Recreation (AAHPER) rules for girls and women's basketball, July 1972 - July 1973 are listed. Exact court measurements are given as are official scoring rules, timing procedures, duties of officials, definition of playing terms, violations and penalties, and officials' signals.…

  19. 12 CFR 701.33 - Reimbursement, insurance, and indemnification of officials and employees.

    Science.gov (United States)

    2010-01-01

    ... specifically excludes: (i) Payment (by reimbursement to an official or direct credit union payment to a third... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Reimbursement, insurance, and indemnification... Reimbursement, insurance, and indemnification of officials and employees. (a) Official. An official is a person...

  20. Semiquantum secret sharing using entangled states

    International Nuclear Information System (INIS)

    Li Qin; Chan, W. H.; Long Dongyang

    2010-01-01

    Secret sharing is a procedure for sharing a secret among a number of participants such that only the qualified subsets of participants have the ability to reconstruct the secret. Even in the presence of eavesdropping, secret sharing can be achieved when all the members are quantum. So what happens if not all the members are quantum? In this paper, we propose two semiquantum secret sharing protocols by using maximally entangled Greenberger-Horne-Zeilinger-type states in which quantum Alice shares a secret with two classical parties, Bob and Charlie, in a way that both parties are sufficient to obtain the secret, but one of them cannot. The presented protocols are also shown to be secure against eavesdropping.

  1. Probabilistic Infinite Secret Sharing

    OpenAIRE

    Csirmaz, László

    2013-01-01

    The study of probabilistic secret sharing schemes using arbitrary probability spaces and possibly infinite number of participants lets us investigate abstract properties of such schemes. It highlights important properties, explains why certain definitions work better than others, connects this topic to other branches of mathematics, and might yield new design paradigms. A probabilistic secret sharing scheme is a joint probability distribution of the shares and the secret together with a colle...

  2. 39 CFR 273.6 - Evaluation by reviewing official.

    Science.gov (United States)

    2010-07-01

    ... supports the allegations of liability; (4) An estimate of the amount of money or the value of property or...)(4) and (5) of this section, the Reviewing Official recommends be demanded from the person alleged to... PROGRAM FRAUD CIVIL REMEDIES ACT § 273.6 Evaluation by reviewing official. (a) Based upon the...

  3. 25 CFR 39.408 - What are the responsibilities of administrative officials?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false What are the responsibilities of administrative officials... INDIAN SCHOOL EQUALIZATION PROGRAM Accountability § 39.408 What are the responsibilities of administrative officials? Administrative officials have the following responsibilities: (a) Applying the...

  4. 32 CFR 1806.3 - Procedures governing acceptance of service of process.

    Science.gov (United States)

    2010-07-01

    ... COUNTERINTELLIGENCE CENTER PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1806.3 Procedures governing acceptance of service of process. (a) Service of Process Upon the NACIC or a NACIC Employee in an Official..., personal service of process may be accepted only by NACIC Counsel, Director, NACIC, or Deputy Director...

  5. 34 CFR 668.37 - Selective Service registration.

    Science.gov (United States)

    2010-07-01

    ... Secretary processes a male student's FAFSA, the Secretary determines whether the student is registered with... Selective Service Act. The designated official shall not consider challenges based on constitutional or...

  6. Statistical results 1988-1990 of the Official Personal Dosimetry Service and data compilation 1980-1990

    International Nuclear Information System (INIS)

    Boerner, E.; Drexler, G.; Scheibe, D.; Schraube, H.

    1994-01-01

    The report consists of a summary of relevant statistical data in the official personal dosimetry in 1988-1990 for the Federal States of Bavaria, Hesse, Schleswig-Holstein, and since 1989, Baden-Wuerttemberg. The data are based on the survey of more than 8000 institutions with over 100000 occupational exposed persons and are derived from more than one million single measurements. The report covers informations on the institutions, on the persons as well as dosimetric values. The measuring method is described briefly with respect to dosimeters used, their range and the interpretation of values. Information on notional doses and the interpolation of values nearby the detection limits are given. (HP) [de

  7. 5 CFR 610.123 - Travel on official time.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Travel on official time. 610.123 Section... DUTY Weekly and Daily Scheduling of Work Work Schedules § 610.123 Travel on official time. Insofar as practicable travel during nonduty hours shall not be required of an employee. When it is essential that this...

  8. Influences of Training on Individual Outcomes for High School Sports Officials

    Directory of Open Access Journals (Sweden)

    Timothy D. Ryan

    2014-04-01

    Full Text Available The primary purpose of this study was to explore the influences of training on specific quality of work outcomes of job satisfaction, pay satisfaction, and intentions to leave within high school sports officials. Evidence suggests that there is a shortage of high school officials in all categories of high school sport. Via a web-based survey, we explored the effects of training on the individual outcomes under study. Results indicated that the level of training had a significant effect on job satisfaction, pay satisfaction, and turnover intentions. Analyses indicated that officials with less training had higher turnover intentions and lower job satisfaction than officials who had more training. Conversely, officials who engaged numerous training hours had lower pay satisfaction. This exploratory study supports the importance of training high school officials but, more importantly, provides an initial assessment on the reverse effects of training on pay satisfaction.

  9. RSA-Based Secret Handshakes

    OpenAIRE

    Vergnaud , Damien

    2006-01-01

    A secret handshake mechanism allows two entities, members of a same group, to authenticate each other secretly. This primitive was introduced recently by Balfanz, Durfee, Shankar, Smetters, Staddon and Wong and, so far, all the schemes proposed are based on discrete log systems. This paper proposes three new secret handshake protocols secure against active impersonator and detector adversaries. Inspired by two RSA-based key agreement protocols introduced by Okamoto and Tanaka in 1989 and Gira...

  10. 47 CFR 1.359 - Proof of official record; authentication of copy.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Proof of official record; authentication of copy. 1.359 Section 1.359 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL PRACTICE AND PROCEDURE Hearing Proceedings Evidence § 1.359 Proof of official record; authentication of copy. An official...

  11. 32 CFR 1904.3 - Procedures governing acceptance of service of process.

    Science.gov (United States)

    2010-07-01

    ... INTELLIGENCE AGENCY PROCEDURES GOVERNING ACCEPTANCE OF SERVICE OF PROCESS § 1904.3 Procedures governing acceptance of service of process. (a) Service of Process Upon the CIA or a CIA Employee in An Official..., personal service of process may be accepted only by attorneys of the Office of General Counsel at CIA...

  12. Typology of the governmental services: terminological polemics

    Directory of Open Access Journals (Sweden)

    R. G. Botvinov

    2016-08-01

    On the basis of the text of the Law of Ukraine “On Public Service” the following conclusion can be done that the statutory regulation of the governmental services of Ukraine is substantially insufficient, especially with regard to the fulfillment of governmental functions towards constitutional items. Most of all, this includes the maintenance of the State’s security. According to the author’s opinion, the Law of Ukraine “On Public Service” shall be amended by the chapter “On specialized government service”, which must rule the issues of legal, social and administrative status of the officials of the executive authorities, whose official activities have specific nature. Besides, it is necessary to perform the legal confirmation of the development of the law enforcement service.

  13. Efficient multiparty quantum-secret-sharing schemes

    International Nuclear Information System (INIS)

    Xiao Li; Deng Fuguo; Long Guilu; Pan Jianwei

    2004-01-01

    In this work, we generalize the quantum-secret-sharing scheme of Hillery, Buzek, and Berthiaume [Phys. Rev. A 59, 1829 (1999)] into arbitrary multiparties. Explicit expressions for the shared secret bit is given. It is shown that in the Hillery-Buzek-Berthiaume quantum-secret-sharing scheme the secret information is shared in the parity of binary strings formed by the measured outcomes of the participants. In addition, we have increased the efficiency of the quantum-secret-sharing scheme by generalizing two techniques from quantum key distribution. The favored-measuring-basis quantum-secret-sharing scheme is developed from the Lo-Chau-Ardehali technique [H. K. Lo, H. F. Chau, and M. Ardehali, e-print quant-ph/0011056] where all the participants choose their measuring-basis asymmetrically, and the measuring-basis-encrypted quantum-secret-sharing scheme is developed from the Hwang-Koh-Han technique [W. Y. Hwang, I. G. Koh, and Y. D. Han, Phys. Lett. A 244, 489 (1998)] where all participants choose their measuring basis according to a control key. Both schemes are asymptotically 100% in efficiency, hence nearly all the Greenberger-Horne-Zeilinger states in a quantum-secret-sharing process are used to generate shared secret information

  14. 25 CFR 700.509 - Duties of the designated agency ethics official.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Duties of the designated agency ethics official. 700.509... RELOCATION PROCEDURES Employee Responsibility and Conduct § 700.509 Duties of the designated agency ethics official. The Designated Agency Ethics Official shall coordinate and manage the agency's ethics program...

  15. 78 FR 55244 - Senior Executive Service Performance Review Board; Membership

    Science.gov (United States)

    2013-09-10

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Senior Executive Service Performance Review Board... the membership of the Defense Nuclear Facilities Safety Board (DNFSB) Senior Executive Service (SES... rating of a senior executive's performance, the executive's response, and the higher level official's...

  16. 20 CFR 401.200 - Blood donor locator service.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Blood donor locator service. 401.200 Section... AND INFORMATION Disclosure of Official Records and Information § 401.200 Blood donor locator service... donors whose blood donations show that they are or may be infected with the human immunodeficiency virus...

  17. Official portrait of the STS 61-B crew

    Science.gov (United States)

    1985-01-01

    Official portrait of the STS 61-B crew. Kneeling next to the Official mission emblam are Astronaut Brewster Shaw, Jr., (right), mission commander; and Bryan D. O'Conner (left), pilot. In the back row are (l.-r.) Charles D. Walker, McDonnell Douglas payload specialist; Jerry L. Ross, Mary L. Cleve and Sherwood C. Spring -- all mission specialists; and Rodolfo Neri, Morelos payload specialist.

  18. Secretion management in the mechanically ventilated patient.

    Science.gov (United States)

    Branson, Richard D

    2007-10-01

    Secretion management in the mechanically ventilated patient includes routine methods for maintaining mucociliary function, as well as techniques for secretion removal. Humidification, mobilization of the patient, and airway suctioning are all routine procedures for managing secretions in the ventilated patient. Early ambulation of the post-surgical patient and routine turning of the ventilated patient are common secretion-management techniques that have little supporting evidence of efficacy. Humidification is a standard of care and a requisite for secretion management. Both active and passive humidification can be used. The humidifier selected and the level of humidification required depend on the patient's condition and the expected duration of intubation. In patients with thick, copious secretions, heated humidification is superior to a heat and moisture exchanger. Airway suctioning is the most important secretion removal technique. Open-circuit and closed-circuit suctioning have similar efficacy. Instilling saline prior to suctioning, to thin the secretions or stimulate a cough, is not supported by the literature. Adequate humidification and as-needed suctioning are the foundation of secretion management in the mechanically ventilated patient. Intermittent therapy for secretion removal includes techniques either to simulate a cough, to mechanically loosen secretions, or both. Patient positioning for secretion drainage is also widely used. Percussion and postural drainage have been widely employed for mechanically ventilated patients but have not been shown to reduce ventilator-associated pneumonia or atelectasis. Manual hyperinflation and insufflation-exsufflation, which attempt to improve secretion removal by simulating a cough, have been described in mechanically ventilated patients, but neither has been studied sufficiently to support routine use. Continuous lateral rotation with a specialized bed reduces atelectasis in some patients, but has not been shown

  19. Assuring bridge safety and serviceability in Europe

    Science.gov (United States)

    2010-08-01

    U.S. engineers need advanced tools and protocols to better assess and assure safety and serviceability of bridges. The Federal Highway Administration, American Association of State Highway and Transportation Officials, and National Cooperative Highwa...

  20. Incretin secretion: direct mechanisms

    DEFF Research Database (Denmark)

    Balk-Møller, Emilie; Holst, Jens Juul; Kuhre, Rune Ehrenreich

    2014-01-01

    The incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are secreted from gastro-intestinal K- and L-cells, respectively, and play an important role in post-prandial blood glucose regulation. They do this by direct stimulation of the pancreatic β...... enzyme responsible for incretin degradation (dipeptidyl peptidase-4) is inhibited (drugs are already on the market) while the secretion of endogenous GLP-1 secretion is stimulated at the same time may prove particularly rewarding. In this section we review current knowledge on the mechanisms for direct...

  1. Official CERN holidays | Restaurant opening hours

    CERN Multimedia

    2013-01-01

    Please note that the CERN Restaurants will have the following opening hours during the upcoming holidays: Restaurant #1 will be open from 7 a.m. to 11 p.m. on Wednesday 1 May, Thursday 9 May (Ascension Thursday) and Monday 20 May (Pentecost) - on Friday 10 May the restaurant will be open at the usual times. Restaurant #2 will be closed over the 3 official CERN holidays, but will be open on Friday 10 May at the usual times (brasserie will be closed). Restaurant #3 will be closed over the 3 official CERN holidays, as well as Friday 10 May.

  2. Stressors among South African soccer officials: A profile analysis ...

    African Journals Online (AJOL)

    The purpose of this study was to determine the contribution of selected stressors to the level of stress experienced by South African soccer officials. Forty-two South African Football Association (SAFA) accredited officials, attending a training camp in Potchefstroom, participated in this study. The group comprised of 40 male ...

  3. Toward Global Comparability of Sexual Orientation Data in Official Statistics: A Conceptual Framework of Sexual Orientation for Health Data Collection in New Zealand's Official Statistics System

    Science.gov (United States)

    Gray, Alistair; Veale, Jaimie F.; Binson, Diane; Sell, Randell L.

    2013-01-01

    Objective. Effectively addressing health disparities experienced by sexual minority populations requires high-quality official data on sexual orientation. We developed a conceptual framework of sexual orientation to improve the quality of sexual orientation data in New Zealand's Official Statistics System. Methods. We reviewed conceptual and methodological literature, culminating in a draft framework. To improve the framework, we held focus groups and key-informant interviews with sexual minority stakeholders and producers and consumers of official statistics. An advisory board of experts provided additional guidance. Results. The framework proposes working definitions of the sexual orientation topic and measurement concepts, describes dimensions of the measurement concepts, discusses variables framing the measurement concepts, and outlines conceptual grey areas. Conclusion. The framework proposes standard definitions and concepts for the collection of official sexual orientation data in New Zealand. It presents a model for producers of official statistics in other countries, who wish to improve the quality of health data on their citizens. PMID:23840231

  4. 32 CFR 516.10 - Service of civil process within the United States.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Service of civil process within the United States... CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Service of Process § 516.10 Service of civil process within the United States. (a) Policy. DA officials will not prevent or evade the service or process in...

  5. Nonlinear secret image sharing scheme.

    Science.gov (United States)

    Shin, Sang-Ho; Lee, Gil-Je; Yoo, Kee-Young

    2014-01-01

    Over the past decade, most of secret image sharing schemes have been proposed by using Shamir's technique. It is based on a linear combination polynomial arithmetic. Although Shamir's technique based secret image sharing schemes are efficient and scalable for various environments, there exists a security threat such as Tompa-Woll attack. Renvall and Ding proposed a new secret sharing technique based on nonlinear combination polynomial arithmetic in order to solve this threat. It is hard to apply to the secret image sharing. In this paper, we propose a (t, n)-threshold nonlinear secret image sharing scheme with steganography concept. In order to achieve a suitable and secure secret image sharing scheme, we adapt a modified LSB embedding technique with XOR Boolean algebra operation, define a new variable m, and change a range of prime p in sharing procedure. In order to evaluate efficiency and security of proposed scheme, we use the embedding capacity and PSNR. As a result of it, average value of PSNR and embedding capacity are 44.78 (dB) and 1.74t⌈log2 m⌉ bit-per-pixel (bpp), respectively.

  6. Shamir secret sharing scheme with dynamic access structure (SSSDAS). Case study on nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Thiyagarajan, P.; Thandra, Prasanth Kumar; Rajan, J.; Satyamurthy, S.A.V. [Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam (India). Computer Div.; Aghila, G. [National Institute of Technology, Karaikal (India). Dept. of Computer Science and Engineering

    2015-05-15

    In recent years, due to the sophistication offered by the Internet, strategic organizations like nuclear power plants are linked to the outside world communication through the Internet. The entry of outside world communication into strategic organization (nuclear power plant) increases the hacker's attempts to crack its security and to trace any information which is being sent among the top level officials. Information security system in nuclear power plant is very crucial as even small loophole in the security system will lead to a major disaster. Recent cyber attacks in nuclear power plant provoked information security professionals to look deeply into the information security aspects of strategic organizations (nuclear power plant). In these lines, Shamir secret sharing scheme with dynamic access structure (SSSDAS) is proposed in the paper which provides enhanced security by providing dynamic access structure for each node in different hierarchies. The SSSDAS algorithm can be applied to any strategic organizations with hierarchical structures. In this paper the possible scenarios where SSSDAS algorithm can be applied to nuclear power plant is explained as a case study. The proposed SSSDAS scheme identifies the wrong shares, if any, used for reconstruction of the secret. The SSSDAS scheme also address the three major security parameters namely confidentiality, authentication and integrity.

  7. Shamir secret sharing scheme with dynamic access structure (SSSDAS). Case study on nuclear power plant

    International Nuclear Information System (INIS)

    Thiyagarajan, P.; Thandra, Prasanth Kumar; Rajan, J.; Satyamurthy, S.A.V.; Aghila, G.

    2015-01-01

    In recent years, due to the sophistication offered by the Internet, strategic organizations like nuclear power plants are linked to the outside world communication through the Internet. The entry of outside world communication into strategic organization (nuclear power plant) increases the hacker's attempts to crack its security and to trace any information which is being sent among the top level officials. Information security system in nuclear power plant is very crucial as even small loophole in the security system will lead to a major disaster. Recent cyber attacks in nuclear power plant provoked information security professionals to look deeply into the information security aspects of strategic organizations (nuclear power plant). In these lines, Shamir secret sharing scheme with dynamic access structure (SSSDAS) is proposed in the paper which provides enhanced security by providing dynamic access structure for each node in different hierarchies. The SSSDAS algorithm can be applied to any strategic organizations with hierarchical structures. In this paper the possible scenarios where SSSDAS algorithm can be applied to nuclear power plant is explained as a case study. The proposed SSSDAS scheme identifies the wrong shares, if any, used for reconstruction of the secret. The SSSDAS scheme also address the three major security parameters namely confidentiality, authentication and integrity.

  8. Marriage, Science, and Secret Intelligence in the life of Rudyerd Boulton (1901-1983: An American in Africa

    Directory of Open Access Journals (Sweden)

    Nancy J. Jacobs

    Full Text Available W. Rudyerd Boulton was a museum ornithologist in New York, Pittsburgh and Chicago who became a specialist in the birds of Africa, notably Angola. He participated in several expeditions to Africa and the Americas, but published little. With the onset of World War II, he joined the newly formed US intelligence and espionage agency, the Office of Strategic Services. He became head of the Secret Intelligence desk for Africa and was connected to the top-secret import of Congolese uranium for atomic bomb development. His postwar career remains largely classified, but in 1953 he was employed in a personnel office of the Central Intelligence Agency. Retired in 1958, he then moved to Southern Rhodesia, where he managed the Atlantica Foundation, an organisation of his own making, which appeared to have extensive funding of unknown origins. Boulton spent the rest of his life on his 'ecological research station', a farm outside Salisbury that he offered to American and Rhodesian scientists as a research base. A retired CIA official who moved to Africa during decolonisation is inherently suspicious. Despite exhaustive efforts, Boultons continuing connection to Washington could not be documented. In fact, several indications - including his own managerial shortcomings - argue against the conclusion that he moved to Africa as a CIA plant. This paper provides an alternative explanation for his relocation, that it was the organic culmination of decades of self-construction effected through three marriages to accomplished women, two of whom were wealthy. Through his partnerships with Laura Craytor, Inez Cunningham Stark, and Louise Rehm, he developed into an expert on African nature, a liberal on American racial matters, and a wealthy patron of scientific work. Evidence of Boultons intelligence gathering may yet turn up, but for now the intimate politics of his life provides a better way to explain his relocation to Africa. Although American interests cannot

  9. Shared Secrets versus Secrets Kept Private Are Linked to Better Adolescent Adjustment

    Science.gov (United States)

    Frijns, Tom; Finkenauer, Catrin; Keijsers, Loes

    2013-01-01

    It is a household notion that secrecy is bad while sharing is good. But what about shared secrets? The present research adopts a functional analysis of sharing secrets, arguing that it should negate harmful consequences generally associated with secrecy and serves important interpersonal functions in adolescence. A survey study among 790 Dutch…

  10. 7 CFR 97.900 - Form of official identification symbol.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Form of official identification symbol. 97.900 Section... symbol. The symbol set forth in Figure 1, containing the words “Plant Variety Protection Office” and “U.S. Department of Agriculture,” shall be the official identification symbol of the Plant Variety Protection...

  11. Training Law Enforcement Officials on Responding to Equine Calls

    Science.gov (United States)

    Anderson, Kathleen P.; Stauffer, Gary; Stauffer, Monte; Anderson, Doug; Biodrowski, Kristie

    2016-01-01

    The occurrence of equine abuse/neglect cases is an ongoing issue. However, officials responding to equine cases are rarely experienced in handling horses. Therefore, workshops teaching basic horse husbandry were offered to better equip and prepare officials to respond to equine cases. Trainings consisted of both classroom and hands-on sessions.…

  12. 7 CFR 56.35 - Authority to use, and approval of official identification.

    Science.gov (United States)

    2010-01-01

    ... of labels or packaging materials bearing official identification or denial of the benefits of the Act.... No label, container, or packaging material bearing official identification may be printed or prepared... with this part. Packaging materials bearing official identification marks shall be approved pursuant to...

  13. On alternative approach for verifiable secret sharing

    OpenAIRE

    Kulesza, Kamil; Kotulski, Zbigniew; Pieprzyk, Joseph

    2002-01-01

    Secret sharing allows split/distributed control over the secret (e.g. master key). Verifiable secret sharing (VSS) is the secret sharing extended by verification capacity. Usually verification comes at the price. We propose "free lunch", the approach that allows to overcome this inconvenience.

  14. Preparticipation Screening of Athletic Officials: SEC Football Referees at Risk.

    Science.gov (United States)

    Turner, John L; Walters, Rod; Leski, Mark J; Saywell, Robert M; Wooldridge, J Scott

    2003-03-01

    Although preparticipation screening for athletes is commonplace, few studies have addressed the issue for those officiating at games. To review current data on physiologic stress on sports officials, to obtain prevalence data on health parameters for football officials, and to determine the outcomes when screening criteria are applied in preseason exams. A protocol was established using health history questionnaires and physical exams with laboratory screening to assess the health of all football officials working in the Southeastern Conference (SEC) from 1997 to 2000. The main outcome measure was the prevalence of cardiac risk factors as determined by American College of Sports Medicine guidelines. Initial screening of 102 football officials revealed that 10.1% of SEC referees had elevated systolic blood pressure, 13.9% had elevated diastolic blood pressure, and 3.8% had resting tachycardia. Average body mass index (BMI) was 28.6 kg/m2, with 87.3% having a BMI that exceeded 25 (overweight). About one-third (31.6%) had a BMI greater than 30 (obese). Total fasting cholesterol exceeded 200 mg/dL in 44.2%, HDL levels were below 35 mg/dL in 34.3%, and LDL levels were above 120 mg/dL in 62.3%. Compared with age-adjusted national data, there were more overweight and more obese officials, but they had lower systolic and diastolic blood pressures and lower mean total cholesterol levels. Using the Framingham Study prediction model to estimate coronary heart disease (CHD) risk, analysis revealed that referees had a lower risk than the national 10-year CHD risk but a higher risk compared with that of the low-risk population. These data reveal a greater need for graded exercise testing. The higher rates of obesity among officials will promote further screening for CHD risk factors.

  15. Immunity ratione materiae of foreign state officials before Rwandan ...

    African Journals Online (AJOL)

    The article seeks to determine when, as a matter of international law, foreign state officials should be granted immunity ratione materiae when they are sued in civil and criminal proceedings in Rwanda. It also investigates the questions as to whether this immunity can be waived by the state on behalf of which the official ...

  16. Trade Secrets in Life Science and Pharmaceutical Companies

    Science.gov (United States)

    Nealey, Tara; Daignault, Ronald M.; Cai, Yu

    2015-01-01

    Trade secret protection arises under state common law and state statutes. In general, a trade secret is information that is not generally known to the public and is maintained as a secret, and it provides a competitive advantage or economic benefit to the trade secret holder. Trade secrets can be worth tens or hundreds of millions of dollars, and damage awards in trade secret litigation have been high; often, there is a lot at stake. Obtaining a trade secret through “improper means” is misappropriation. If the alleged trade secret, however, was developed independently, known publicly, or not maintained as a secret, then those defenses may successfully overcome a claim for trade secret misappropriation. With today’s interconnectedness in the biotechnology and pharmaceutical fields, more collaborations, joint ventures, and outsourcing arrangements among firms, and increased mobility of employees’ careers, life science companies need to not only understand how to protect their trade secrets, but also know how to defend against a claim for trade secret theft. PMID:25414378

  17. Trade secrets in life science and pharmaceutical companies.

    Science.gov (United States)

    Nealey, Tara; Daignault, Ronald M; Cai, Yu

    2014-11-20

    Trade secret protection arises under state common law and state statutes. In general, a trade secret is information that is not generally known to the public and is maintained as a secret, and it provides a competitive advantage or economic benefit to the trade secret holder. Trade secrets can be worth tens or hundreds of millions of dollars, and damage awards in trade secret litigation have been high; often, there is a lot at stake. Obtaining a trade secret through "improper means" is misappropriation. If the alleged trade secret, however, was developed independently, known publicly, or not maintained as a secret, then those defenses may successfully overcome a claim for trade secret misappropriation. With today's interconnectedness in the biotechnology and pharmaceutical fields, more collaborations, joint ventures, and outsourcing arrangements among firms, and increased mobility of employees' careers, life science companies need to not only understand how to protect their trade secrets, but also know how to defend against a claim for trade secret theft. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

  18. Two-party secret key distribution via a modified quantum secret sharing protocol.

    Science.gov (United States)

    Grice, W P; Evans, P G; Lawrie, B; Legré, M; Lougovski, P; Ray, W; Williams, B P; Qi, B; Smith, A M

    2015-03-23

    We present and demonstrate a novel protocol for distributing secret keys between two and only two parties based on N-party single-qubit Quantum Secret Sharing (QSS). We demonstrate our new protocol with N = 3 parties using phase-encoded photons. We show that any two out of N parties can build a secret key based on partial information from each other and with collaboration from the remaining N - 2 parties. Our implementation allows for an accessible transition between N-party QSS and arbitrary two party QKD without modification of hardware. In addition, our approach significantly reduces the number of resources such as single photon detectors, lasers and dark fiber connections needed to implement QKD.

  19. Blazing the trail: Official Report : Singapore 2010 Youth Olympic Games

    OpenAIRE

    2012-01-01

    The official report of the 1st Youth Olympic Games, “Blazing the trail: Official Report: Singapore 2010 Youth Olympic Games” consisted of one volume, published in French and English. The French version was published only in electronic form

  20. 9 CFR 590.412 - Form of official identification symbol and inspection mark.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Form of official identification symbol... PRODUCTS INSPECTION ACT) Identifying and Marking Product § 590.412 Form of official identification symbol... official identification symbol for purposes of this part and, when used, imitated, or simulated in any...

  1. Monitoring Salivary Immunoglobulin A Responses to Official and Simulated Matches In Elite Young Soccer Players

    Directory of Open Access Journals (Sweden)

    Freitas Camila G.

    2016-12-01

    Full Text Available The purpose of the present study was to examine SIgA responses (concentration [SIgAabs] and a secretion rate [SIgArate] to official and simulated competitive matches in young soccer players. The sample was composed of 26 male soccer players (age 15.6 ± 1.1 yrs, stature 177.0 ± 6.1 cm, body mass 70.5 ± 5.7 kg. Four soccer matches (two simulated matches [SM] and two official matches [OM] were conducted. The matches consisted of two halves of 35 min with a 10 min rest interval. Each assessed player participated in only one SM and one OM. All matches were performed in the same week, during the competitive season, and at the same time of the day (9:00 am, separated by 48 h. Saliva samples were collected before and after every match. The session rating of perceived exertion was reported 30 min after each match in order to determine the internal training load (ITL. A significant decrease in SIgAabs and SIgArate after OM was observed when compared to the pre-match value. In addition, the SIgArate was higher at pre-OM when compared to pre-SM. A higher ITL for OM was observed compared to SM. The current findings indicate that OM may lead to a decrease in the main mucosal immunity function parameter of young soccer players that could increase the risk of URTI. Coaches should be aware of it in order to plan appropriate training loads and recovery procedures to avoid or minimize the likelihood of upper respiratory tract infection occurrences.

  2. 28 CFR 68.41 - Official notice.

    Science.gov (United States)

    2010-07-01

    ... ALIENS, UNFAIR IMMIGRATION-RELATED EMPLOYMENT PRACTICES, AND DOCUMENT FRAUD § 68.41 Official notice... so noticed, and shall be given adequate opportunity to show the contrary. [54 FR 48596, Nov. 24, 1989...

  3. Toward Global Comparability of Sexual Orientation Data in Official Statistics: A Conceptual Framework of Sexual Orientation for Health Data Collection in New Zealand’s Official Statistics System

    Directory of Open Access Journals (Sweden)

    Frank Pega

    2013-01-01

    Full Text Available Objective. Effectively addressing health disparities experienced by sexual minority populations requires high-quality official data on sexual orientation. We developed a conceptual framework of sexual orientation to improve the quality of sexual orientation data in New Zealand’s Official Statistics System. Methods. We reviewed conceptual and methodological literature, culminating in a draft framework. To improve the framework, we held focus groups and key-informant interviews with sexual minority stakeholders and producers and consumers of official statistics. An advisory board of experts provided additional guidance. Results. The framework proposes working definitions of the sexual orientation topic and measurement concepts, describes dimensions of the measurement concepts, discusses variables framing the measurement concepts, and outlines conceptual grey areas. Conclusion. The framework proposes standard definitions and concepts for the collection of official sexual orientation data in New Zealand. It presents a model for producers of official statistics in other countries, who wish to improve the quality of health data on their citizens.

  4. 5 CFR 1312.27 - Top secret control.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Top secret control. 1312.27 Section 1312... Classified Information § 1312.27 Top secret control. The EOP Security Officer serves as the Top Secret... Top Secret material. The ATSCOs will be responsible for the accountability and custodianship of Top...

  5. Effect of adrenal hormones on thyroid secretion and thyroid hormones on adrenal secretion in the sheep.

    Science.gov (United States)

    Falconer, I R; Jacks, F

    1975-01-01

    1. Previous work has shown that after stressful stimuli, sheep initially secrete increased amounts of thyroid hormone, at a time when adrenal secretion is also elevated. 2. This study was designed to evaluate (a) any short-term activation or inhibition of thyroid secretion by exogenous cortisol or ACTH administered in quantities comparable to those secreted after stress in sheep and (b) any short-term effect that exogenous thyroxine or triiodothyronine may have on the concentration of plasma cortisol in the sheep. 3. Thyroid activity was measured by determination of plasma protein bound 125I (PB125I) and total 125I in thyroid vein and mixed venous (jugular) blood. Plasma cortisol and thyroxine concentrations were measured by a competitive protein-binding assay at intervals for up to 5 hr after commencement of the experiment. 4. No evidence of an activation of thyroid secretion was found during cortisol or ACTH infusion, as monitored by thyroid vein PB125I. Similarly there was no evidence of any inhibition of thyroid function, as measured by continued secretion of thyroid hormones into thyroid vein blood. 5. No effect on plasma cortisol concentration due to thyroid hormone treatment was observed. 6. It was concluded that (a) elevated circulating corticosteroids in physiological concentrations have no short-term effects on thyroid activity in the sheep and (b) the short-term alterations in thyroid and adrenal cortical secretion observed during stress in the sheep could not be attributed to direct interaction of elevated thyroid hormone concentrations with adrenal cortical secretion. PMID:170400

  6. 9 CFR 592.310 - Form of official identification symbol and inspection mark.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Form of official identification symbol... Identifying and Marking Products § 592.310 Form of official identification symbol and inspection mark. (a) The shield set forth in Figure 1, containing the letters “USDA,” shall be the official identification symbol...

  7. Twenty-one Ways to Develop Esprit De Corps Among Your Student Officials.

    Science.gov (United States)

    Kovalakides, Nick

    Student officials for intramural sports can be given special training to enhance their aptitude in the field, but their attitude is more difficult to develop. This paper suggests 21 ways to develop attitude among student officials. Some of the suggestions are: Athletic departments should emphasize the role of the official in the intramural…

  8. Secretion Trap Tagging of Secreted and Membrane-Spanning Proteins Using Arabidopsis Gene Traps

    Science.gov (United States)

    Andrew T. Groover; Joseph R. Fontana; Juana M. Arroyo; Cristina Yordan; W. Richard McCombie; Robert A. Martienssen

    2003-01-01

    Secreted and membrane-spanning proteins play fundamental roles in plant development but pose challenges for genetic identification and characterization. We describe a "secretion trap" screen for gene trap insertions in genes encoding proteins routed through the secretory pathway. The gene trap transposon encodes a ß-glucuronidase reporter enzyme...

  9. Alternative protein secretion: The Mam1 ABC transporter supports secretion of M-factor linked GFP in fission yeast

    International Nuclear Information System (INIS)

    Kjaerulff, Soren; Mueller, Sven; Jensen, Martin Roland

    2005-01-01

    To examine whether the fission yeast Mam1 ABC transporter can be used for secretion of heterologous proteins, thereby bypassing the classical secretion pathway, we have analyzed chimeric forms of the M-factor precursor. It was demonstrated that GFP can be exported when fused to both the amino-terminal prosequence from mfm1 and a CaaX motif. This secretion was dependent on the Mam1 transporter and not the classical secretion pathway. The secretion efficiency of GFP, however, was relatively low and most of the reporter protein was trapped in the vacuolar membranes. Our findings suggest that the Mam1 ABC protein is a promiscuous peptide transporter that can accommodate globular proteins of a relatively large size. Furthermore, our results help in defining the sequences required for processing and secretion of natural M-factor

  10. 29 CFR 401.11 - Secret ballot.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Secret ballot. 401.11 Section 401.11 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR LABOR-MANAGEMENT STANDARDS MEANING OF TERMS USED IN THIS SUBCHAPTER § 401.11 Secret ballot. Secret ballot means the expression by...

  11. Communication from Goods Reception services

    CERN Multimedia

    2007-01-01

    Members of the personnel are invited to take note that only parcels corresponding to official orders or contracts will be handled at CERN. Individuals are not authorised to have private merchandise delivered to them at CERN and private deliveries will not be accepted by the Goods Reception services. Thank you for your understanding.

  12. What Is Technology Education? A Review of the "Official Curriculum"

    Science.gov (United States)

    Brown, Ryan A.; Brown, Joshua W.

    2010-01-01

    Technology education, not to be confused with educational technology, has an "official curriculum." This article explores this "official curriculum" and answers the following questions; what are the goals of technology education, what should technology education look like in classrooms, and why technology education is important. This article…

  13. 29 CFR 1202.4 - Secret ballot.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Secret ballot. 1202.4 Section 1202.4 Labor Regulations Relating to Labor (Continued) NATIONAL MEDIATION BOARD RULES OF PROCEDURE § 1202.4 Secret ballot. In conducting such investigation, the Board is authorized to take a secret ballot of the employees involved, or...

  14. The Secret of Future Victories

    Science.gov (United States)

    1992-02-01

    Copy S of 320 copies AD--A25 0 718 IDA PAPER P-265 3 THE SECRET OF FUTURE VICTORIES Paul F. Gormnan General, USA (Retired) DTIC 05M February 1992 NAY...TYPE AND DATES COVERED IFebruary 1992 Final--June 1991-January 1992 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS The Secret of Future Victories C -MDA...8 2N0-102 IDA PAPER P-2653 THE SECRET OF FUTURE VICTORIES Paul F. Gorman General. LUSA (Retired) February 1992 Approved for public release

  15. Current Therapies That Modify Glucagon Secretion

    DEFF Research Database (Denmark)

    Grøndahl, Magnus F.; Keating, Damien J.; Vilsbøll, Tina

    2017-01-01

    and provide insights into how antidiabetic drugs influence glucagon secretion as well as a perspective on the future of glucagon-targeting drugs. Recent Findings: Several older as well as recent investigations have evaluated the effect of antidiabetic agents on glucagon secretion to understand how glucagon...... may be involved in the drugs’ efficacy and safety profiles. Based on these findings, modulation of glucagon secretion seems to play a hitherto underestimated role in the efficacy and safety of several glucose-lowering drugs. Summary: Numerous drugs currently available to diabetologists are capable...... of altering glucagon secretion: metformin, sulfonylurea compounds, insulin, glucagon-like peptide-1 receptor agonists, dipeptidyl peptidase-4 inhibitors, sodium-glucose cotransporter 2 inhibitors and amylin mimetics. Their diverse effects on glucagon secretion are of importance for their individual efficacy...

  16. Characterization of a secreted Chlamydia protease

    DEFF Research Database (Denmark)

    Shaw, A.C.; Vandahl, B.B.; Larsen, M.R.

    2002-01-01

    Chlamydiae are obligate intracellular bacteria that are important human pathogens. The Chlamydia genomes contain orthologues to secretion apparatus proteins from other intracellular bacteria, but only a few secreted proteins have been identified. Most likely, effector proteins are secreted in order...... to promote infection. Effector proteins cannot be identified by motif or similarity searches. As a new strategy for identification of secreted proteins we have compared 2D-PAGE profiles of [35S]-labelled Chlamydia proteins from whole lysates of infected cells to 2D-PAGE profiles of proteins from purified...... Chlamydia. Several secretion candidates from Chlamydia trachomatis D and Chlamydia pneumoniae were detected by this method. Two protein spots were identified among the candidates. These represent fragments of the 'chlamydial protease- or proteasome-like activity factor' (CPAF) and were clearly present in 2D...

  17. EFFECTS OF SECRETABLE PLACENTAL FACTORS UPON SECRETION OF CYTOKINES BY THP-1 MONOCYTE-LIKE CELLS

    Directory of Open Access Journals (Sweden)

    Ya. S. Onokhina

    2013-01-01

    Full Text Available Abstract. Мonocytes in feto-placental circulation are exposed to factors secreted by placental tissue. These factors influence monocyte functions in pregnancy. In present study, an in vitro model (monocyte-like THP-1 cells was used for assessing effects of soluble placental factors obtained from women with physiological pregnancies, or preeclampsia cases. The following effects of placental factors were revealed: increased secretion of VEGF by THP-1 cells along with decreased secretion of IL-6, IL-8 and MCP-1 under the influence of placental factors from the I. trimester of pregnancy in comparison with III. trimester. Secretion of IL-6 and MCP-1 by THP-1 cells was increased, and secretion of soluble TNFRII was decreased upon co-cultivation with soluble placental factors from the women with preeclampsia, as compared with placental products from physiological pregnancies.The work is supported by grants ГК № 02.740.11.0711 from Ministry of Education and Science, and НШ-3594.2010.7 grant from the President of Russian Federation.

  18. 5 CFR 2421.15 - Secret ballot.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Secret ballot. 2421.15 Section 2421.15... FEDERAL LABOR RELATIONS AUTHORITY MEANING OF TERMS AS USED IN THIS SUBCHAPTER § 2421.15 Secret ballot. Secret ballot means the expression by ballot, voting machine or otherwise, but in no event by proxy, of a...

  19. 29 CFR 452.97 - Secret ballot.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 2 2010-07-01 2010-07-01 false Secret ballot. 452.97 Section 452.97 Labor Regulations... OF 1959 Election Procedures; Rights of Members § 452.97 Secret ballot. (a) A prime requisite of elections regulated by title IV is that they be held by secret ballot among the members or in appropriate...

  20. 6 CFR 13.16 - Disqualification of Reviewing Official or ALJ.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Disqualification of Reviewing Official or ALJ. 13.16 Section 13.16 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.16 Disqualification of Reviewing Official or ALJ. (a) A Reviewing...

  1. 10 CFR 1045.33 - Appointment of restricted data management official.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Appointment of restricted data management official. 1045... DECLASSIFICATION Generation and Review of Documents Containing Restricted Data and Formerly Restricted Data § 1045.33 Appointment of restricted data management official. (a) Each agency with access to RD or FRD shall...

  2. 28 CFR 8.2 - Designation of officials having seizure authority.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Designation of officials having seizure... CERTAIN STATUTES § 8.2 Designation of officials having seizure authority. The Director, Associate Director... Investigation are authorized to seize such property as may be subject to seizure pursuant to statutes identified...

  3. Secretive eating among youth with overweight or obesity.

    Science.gov (United States)

    Kass, Andrea E; Wilfley, Denise E; Eddy, Kamryn T; Boutelle, Kerri N; Zucker, Nancy; Peterson, Carol B; Le Grange, Daniel; Celio-Doyle, Angela; Goldschmidt, Andrea B

    2017-07-01

    Secretive eating, characterized by eating privately to conceal being seen, may reflect eating- and/or body-related shame, be associated with depression, and correlate with binge eating, which predicts weight gain and eating disorder onset. Increasing understanding of secretive eating in youth may improve weight status and reduce eating disorder risk. This study evaluated the prevalence and correlates of secretive eating in youth with overweight or obesity. Youth (N = 577) presented to five research/clinical institutions. Using a cross-sectional design, secretive eating was evaluated in relation to eating-related and general psychopathology via linear and logistic regression analyses. Secretive eating was endorsed by 111 youth, who were, on average, older than youth who denied secretive eating (mean age = 12.07 ± 2.83 versus 10.97 ± 2.31). Controlling for study site and age, youth who endorsed secretive eating had higher eating-related psychopathology and were more likely to endorse loss of control eating and purging than their counterparts who did not endorse secretive eating. Groups did not differ in excessive exercise or behavioral problems. Dietary restraint and purging were elevated among adolescents (≥13y) but not children (<13y) who endorsed secretive eating; depression was elevated among children, but not adolescents, who endorsed secretive eating. Secretive eating may portend heightened risk for eating disorders, and correlates of secretive eating may differ across pediatric development. Screening for secretive eating may inform identification of problematic eating behaviors, and understanding factors motivating secretive eating may improve intervention tailoring. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma

    International Nuclear Information System (INIS)

    Kim, Mi Young; Kim, Jin Hee; Oh, Young Kee; Kim, El

    2016-01-01

    To investigate treatment outcome and long term complication after surgery and radiotherapy (RT) for pituitary adenoma. From 1990 to 2009, 73 patients with surgery and RT for pituitary adenoma were analyzed in this study. Median age was 51 years (range, 25 to 71 years). Median tumor size was 3 cm (range, 1 to 5 cm) with suprasellar (n = 21), cavernous sinus extension (n = 14) or both (n = 5). Hormone secreting tumor was diagnosed in 29 patients; 16 patients with prolactin, 12 patients with growth hormone, and 1 patient with adrenocorticotrophic hormone. Impairment of visual acuity or visual field was presented in 33 patients at first diagnosis. Most patients (n = 64) received RT as postoperative adjuvant setting. Median RT dose was 45 Gy (range, 45 to 59.4 Gy). Median follow-up duration was 8 years (range, 3 to 22 years). In secreting tumors, hormone normalization rate was 55% (16 of 29 patients). For 25 patients with evaluable visual field and visual acuity test, 21 patients (84%) showed improvement of visual disturbance after treatment. The 10-year tumor control rate for non-secreting and secreting adenoma was 100% and 58%, respectively (p < 0.001). Progression free survival rate at 10 years was 98%. Only 1 patient experienced endocrinological recurrence. Following surgery, 60% (n = 44) suffered from pituitary function deficit. Late complication associated with RT was only 1 patient, who developed cataract. Surgery and RT are very effective and safe in hormonal and tumor growth control for secreting and non-secreting pituitary adenoma

  5. Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mi Young; Kim, Jin Hee; Oh, Young Kee; Kim, El [Dongsan Medical Center, Keimyung University School of Medicine, Daegu (Korea, Republic of)

    2016-06-15

    To investigate treatment outcome and long term complication after surgery and radiotherapy (RT) for pituitary adenoma. From 1990 to 2009, 73 patients with surgery and RT for pituitary adenoma were analyzed in this study. Median age was 51 years (range, 25 to 71 years). Median tumor size was 3 cm (range, 1 to 5 cm) with suprasellar (n = 21), cavernous sinus extension (n = 14) or both (n = 5). Hormone secreting tumor was diagnosed in 29 patients; 16 patients with prolactin, 12 patients with growth hormone, and 1 patient with adrenocorticotrophic hormone. Impairment of visual acuity or visual field was presented in 33 patients at first diagnosis. Most patients (n = 64) received RT as postoperative adjuvant setting. Median RT dose was 45 Gy (range, 45 to 59.4 Gy). Median follow-up duration was 8 years (range, 3 to 22 years). In secreting tumors, hormone normalization rate was 55% (16 of 29 patients). For 25 patients with evaluable visual field and visual acuity test, 21 patients (84%) showed improvement of visual disturbance after treatment. The 10-year tumor control rate for non-secreting and secreting adenoma was 100% and 58%, respectively (p < 0.001). Progression free survival rate at 10 years was 98%. Only 1 patient experienced endocrinological recurrence. Following surgery, 60% (n = 44) suffered from pituitary function deficit. Late complication associated with RT was only 1 patient, who developed cataract. Surgery and RT are very effective and safe in hormonal and tumor growth control for secreting and non-secreting pituitary adenoma.

  6. Extracellular secretion of a recombinant therapeutic peptide by Bacillus halodurans utilizing a modified flagellin type III secretion system

    CSIR Research Space (South Africa)

    Berger, E

    2011-08-01

    Full Text Available further 3.5-fold increase in the secretion of recombinant peptide fusions. Conclusions: The type III flagellar secretion system of B. halodurans has been shown to successfully secrete a therapeutic peptide as a heterologous flagellin fusion. Improvements...

  7. Pituitary-hormone secretion by thyrotropinomas

    NARCIS (Netherlands)

    Roelfsema, Ferdinand; Kok, Simon; Kok, Petra; Pereira, Alberto M.; Biermasz, Nienke R.; Smit, Jan W.; Frolich, Marijke; Keenan, Daniel M.; Veldhuis, Johannes D.; Romijn, Johannes A.

    2009-01-01

    Hormone secretion by somatotropinomas, corticotropinomas and prolactinomas exhibits increased pulse frequency, basal and pulsatile secretion, accompanied by greater disorderliness. Increased concentrations of growth hormone (GH) or prolactin (PRL) are observed in about 30% of thyrotropinomas leading

  8. A framework for service outsourcing using process views

    NARCIS (Netherlands)

    Eshuis, H.; Norta, A.H.

    2010-01-01

    Service outsourcing is a business paradigm in which an organization has a part of its business process performed by a service provider. Process views are pivotal to support this way of working. A process view shields secret or irrelevant details from a private business process, thus allowing an

  9. A secure data outsourcing scheme based on Asmuth-Bloom secret sharing

    Science.gov (United States)

    Idris Muhammad, Yusuf; Kaiiali, Mustafa; Habbal, Adib; Wazan, A. S.; Sani Ilyasu, Auwal

    2016-11-01

    Data outsourcing is an emerging paradigm for data management in which a database is provided as a service by third-party service providers. One of the major benefits of offering database as a service is to provide organisations, which are unable to purchase expensive hardware and software to host their databases, with efficient data storage accessible online at a cheap rate. Despite that, several issues of data confidentiality, integrity, availability and efficient indexing of users' queries at the server side have to be addressed in the data outsourcing paradigm. Service providers have to guarantee that their clients' data are secured against internal (insider) and external attacks. This paper briefly analyses the existing indexing schemes in data outsourcing and highlights their advantages and disadvantages. Then, this paper proposes a secure data outsourcing scheme based on Asmuth-Bloom secret sharing which tries to address the issues in data outsourcing such as data confidentiality, availability and order preservation for efficient indexing.

  10. Normal and abnormal secretion by haemopoietic cells

    Science.gov (United States)

    STINCHCOMBE, JANE C; GRIFFITHS, GILLIAN M

    2001-01-01

    The secretory lysosomes found in haemopoietic cells provide a very efficient mechanism for delivering the effector proteins of many immune cells in response to antigen recognition. Although secretion shows some similarities to the secretion of specialized granules in other secretory cell types, some aspects of secretory lysosome release appear to be unique to melanocytes and cells of the haemopoietic lineage. Mast cells and platelets have provided excellent models for studying secretion, but recent advances in characterizing the immunological synapse allow a very fine dissection of the secretory process in T lymphocytes. These studies show that secretory lysosomes are secreted from the centre of the talin ring at the synapse. Proper secretion requires a series of Rab and cytoskeletal elements which play critical roles in the specialized secretion of lysosomes in haemopoietic cells. PMID:11380687

  11. 44 CFR 8.3 - Senior FEMA official responsible for the information security program.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Senior FEMA official... Senior FEMA official responsible for the information security program. The Director of the Security Division, has been designated as the senior official to direct and administer the FEMA information security...

  12. Official Report of the XXVIII Olympiad: Athens 2004

    OpenAIRE

    Skarvelē, Euharēs

    2014-01-01

    The “Official Report of the XXVIII Olympiad: Athens 2004” was published by ATHOC in English and Greek. Based on the same model as for Sydney 2000, this official report consisted of a box set of two printed volumes (Homecoming of the Games - organisation and operations; The Games) and a multimedia set, which offered two bilingual CD-ROMs containing the results, and a DVD of the film “Behind the scenes of the Athens 2004 Opening and Closing Ceremonies”. Vol. 1 Part I: Homecoming of the Games ; ...

  13. Some Economics of Trade Secret Law

    OpenAIRE

    David D. Friedman; William M. Landes; Richard A. Posner

    1991-01-01

    Despite the practical importance of trade secrets to the business community, the law of trade secrets is a neglected orphan in economic analysis. This paper sketches an approach to the economics of trade secret law that connects it more closely both to other areas of intellectual property and to broader issues in the positive economic theory of the common law.

  14. Physiology of bile secretion.

    Science.gov (United States)

    Esteller, Alejandro

    2008-10-07

    The formation of bile depends on the structural and functional integrity of the bile-secretory apparatus and its impairment, in different situations, results in the syndrome of cholestasis. The structural bases that permit bile secretion as well as various aspects related with its composition and flow rate in physiological conditions will first be reviewed. Canalicular bile is produced by polarized hepatocytes that hold transporters in their basolateral (sinusoidal) and apical (canalicular) plasma membrane. This review summarizes recent data on the molecular determinants of this primary bile formation. The major function of the biliary tree is modification of canalicular bile by secretory and reabsorptive processes in bile-duct epithelial cells (cholangiocytes) as bile passes through bile ducts. The mechanisms of fluid and solute transport in cholangiocytes will also be discussed. In contrast to hepatocytes where secretion is constant and poorly controlled, cholangiocyte secretion is regulated by hormones and nerves. A short section dedicated to these regulatory mechanisms of bile secretion has been included. The aim of this revision was to set the bases for other reviews in this series that will be devoted to specific issues related with biliary physiology and pathology.

  15. Environment conservation by way of official notice or recommendations

    International Nuclear Information System (INIS)

    Ossenbuehl, F.

    1986-01-01

    Official notice or recommendations belong to the self-evident instruments of government authorities to fulfill their functions. According to their typical type of effect, in the system of powers to act, these instruments belong to the group of the simple administrative acts of state. They are thus not of direct legal interest, at first sight. However, the Chernobyl accident and its consequences have just been the latest opportunity to realise that official notice or recommendations issued by state authorities may have a far-reaching impact on the consumers' behaviour, and hence on the market situation. The book in hand discusses legal problems in connection with such impact, taking as an example the field of environment conservation and related precautionary activities. The main issues dealt with refer to the permissibility by law and the formal status of official notice warning of the use of environmentally harmful products, to legal protection in case of unlawful warnings or recommendations, and to possible liabilities. The book in hand developed from a legal expertise made on behalf of the German Federation of Toilet Articles and Detergents Producers is intended to show that the increasingly used informal administrative instruments of official notice or recommendations ought to be integrated into the system of administrative law. (orig./HP) [de

  16. Could the United States Reinstitute an Official Torture Policy?

    Directory of Open Access Journals (Sweden)

    Adam Jacobson

    2017-06-01

    Full Text Available In 2015, the United States passed legislation that reaffirmed its ban on using torture and abusive techniques in national security interrogations. However, the Republican president-elect Donald Trump has repeatedly promised to revive torture as official policy, and the idea of torturing suspected terrorists is popular with the American public. Given these facts, what are the vulnerabilities within the current prohibition that makes a return to an official torture policy possible? This paper examines the weaknesses within each branch of government and other factors that could contribute to making a return to official torture by the United States more likely. It shows that the prohibition against torture does face vulnerabilities that can be exploited to reinstitute a torture policy, and that while this may not be likely in the current political environment, it is possible.

  17. Unconventional Pathways of Secretion Contribute to Inflammation

    Directory of Open Access Journals (Sweden)

    Michael J. D. Daniels

    2017-01-01

    Full Text Available In the conventional pathway of protein secretion, leader sequence-containing proteins leave the cell following processing through the endoplasmic reticulum (ER and Golgi body. However, leaderless proteins also enter the extracellular space through mechanisms collectively known as unconventional secretion. Unconventionally secreted proteins often have vital roles in cell and organism function such as inflammation. Amongst the best-studied inflammatory unconventionally secreted proteins are interleukin (IL-1β, IL-1α, IL-33 and high-mobility group box 1 (HMGB1. In this review we discuss the current understanding of the unconventional secretion of these proteins and highlight future areas of research such as the role of nuclear localisation.

  18. Proton pump inhibitors inhibit pancreatic secretion

    DEFF Research Database (Denmark)

    Wang, Jing; Barbuskaite, Dagne; Tozzi, Marco

    2015-01-01

    +/K+-ATPases are expressed and functional in human pancreatic ducts and whether proton pump inhibitors (PPIs) have effect on those. Here we show that the gastric HKα1 and HKβ subunits (ATP4A; ATP4B) and non-gastric HKα2 subunits (ATP12A) of H+/K+-ATPases are expressed in human pancreatic cells. Pumps have similar...... of major ions in secretion follow similar excretory curves in control and PPI treated animals. In addition to HCO3-, pancreas also secretes K+. In conclusion, this study calls for a revision of the basic model for HCO3- secretion. We propose that proton transport is driving secretion, and that in addition...

  19. The Neutron Personal Dosimetry Service of the Centre for Radiation, Chemical and Environmental Hazards, PHE-UK

    International Nuclear Information System (INIS)

    Campo Blanco, X.

    2015-01-01

    The Centre for Radiation, Chemical and Environmental Hazards (CRCEH), that belongs to Public Health England (PHE), hosts the official Neutron Personal Dosimetry Service of the United Kingdom. They use etched-track detectors, made of a material called PADC (poly-allyl diglycol carbonate), to determinate de neutron personal dose. A two weeks visit has been made to this center, in order to learn about the facilities, the methods employed and the legislative framework of the Neutron Personal Dosimetry Service. In this work the main results of this visits are shown, which are interesting for the future development of an official neutron personal dosimetry service in Spain.

  20. Hoopoes color their eggs with antimicrobial uropygial secretions

    Science.gov (United States)

    Soler, Juan J.; Martín-Vivaldi, M.; Peralta-Sánchez, J. M.; Arco, L.; Juárez-García-Pelayo, N.

    2014-09-01

    Uropygial gland secretions are used as cosmetics by some species of birds to color and enhance properties of feathers and teguments, which may signal individual quality. Uropygial secretions also reach eggshells during incubation and, therefore, may influence the coloration of birds' eggs, a trait that has attracted the attention of evolutionary biologists for more than one century. The color of hoopoe eggs typically changes along incubation, from bluish-gray to greenish-brown. Here, we test experimentally the hypothesis that dark uropygial secretion of females is responsible for such drastic color change. Moreover, since uropygial secretion of hoopoes has antimicrobial properties, we also explore the association between color and antimicrobial activity of the uropygial secretion of females. We found that eggs stayed bluish-gray in nests where female access to the uropygial secretion was experimentally blocked. Furthermore, experimental eggs that were maintained in incubators and manually smeared with uropygial secretion experienced similar color changes that naturally incubated eggs did, while control eggs that were not in contact with the secretions did not experience such color changes. All these results strongly support the hypothesis that female hoopoes use their uropygial gland secretion to color the eggs. Moreover, saturation of the uropygial secretion was associated with antimicrobial activity against Bacillus licheniformis. Given the known antimicrobial potential of uropygial secretions of birds, this finding opens the possibility that in scenarios of sexual selection, hoopoes in particular and birds in general signal antimicrobial properties of their uropygial secretion by mean of changes in egg coloration along incubation.

  1. The role of jasmonates in floral nectar secretion.

    Directory of Open Access Journals (Sweden)

    Venkatesan Radhika

    Full Text Available Plants produce nectar in their flowers as a reward for their pollinators and most of our crops depend on insect pollination, but little is known on the physiological control of nectar secretion. Jasmonates are well-known for their effects on senescence, the development and opening of flowers and on plant defences such as extrafloral nectar. Their role in floral nectar secretion has, however, not been explored so far. We investigated whether jasmonates have an influence on floral nectar secretion in oil-seed rape, Brassica napus. The floral tissues of this plant produced jasmonic acid (JA endogenously, and JA concentrations peaked shortly before nectar secretion was highest. Exogenous application of JA to flowers induced nectar secretion, which was suppressed by treatment with phenidone, an inhibitor of JA synthesis. This effect could be reversed by additional application of JA. Jasmonoyl-isoleucine and its structural mimic coronalon also increased nectar secretion. Herbivory or addition of JA to the leaves did not have an effect on floral nectar secretion, demonstrating a functional separation of systemic defence signalling from reproductive nectar secretion. Jasmonates, which have been intensively studied in the context of herbivore defences and flower development, have a profound effect on floral nectar secretion and, thus, pollination efficiency in B. napus. Our results link floral nectar secretion to jasmonate signalling and thereby integrate the floral nectar secretion into the complex network of oxylipid-mediated developmental processes of plants.

  2. The Use of Social Media for Communication In Official Statistics at European Level

    Directory of Open Access Journals (Sweden)

    Ionela-Roxana GLĂVAN

    2016-12-01

    Full Text Available Social media tools are wide spread in web communication and are gaining popularity in the communication process between public institutions and citizens. This study conducts an analysis on how social media is used by Official Statistical Institutes to interact with citizens and disseminate information. A linear regression technique is performed to examine which social media platforms (Twitter or Facebook is a more effective tool in the communication process in the official statistics area. Our study suggests that Twitter is a more powerful tool than Facebook in enhancing the relationship between official statistics and citizens, complying with several other studies. Next, we performed an analysis on Twitter network characteristics discussing “official statistics” using NodeXL that revealed the unexploited potential of this network by official statistical agencies.

  3. 75 FR 53841 - Display of Official Sign; Permanent Increase in Standard Maximum Share Insurance Amount

    Science.gov (United States)

    2010-09-02

    ... to replace the old version of the official sign with the revised official sign at required locations.... Additionally, a credit union must replace the old version of the official sign with the revised official sign... internet signs and deplete its stockpiles of other printed advertising materials. NCUA also believes that...

  4. Secret-key expansion from covert communication

    Science.gov (United States)

    Arrazola, Juan Miguel; Amiri, Ryan

    2018-02-01

    Covert communication allows the transmission of messages in such a way that it is not possible for adversaries to detect that the communication is occurring. This provides protection in situations where knowledge that two parties are talking to each other may be incriminating to them. In this work, we study how covert communication can be used for a different purpose: secret key expansion. First, we show that any message transmitted in a secure covert protocol is also secret and therefore unknown to an adversary. We then propose a covert communication protocol where the amount of key consumed in the protocol is smaller than the transmitted key, thus leading to secure secret key expansion. We derive precise conditions for secret key expansion to occur, showing that it is possible when there are sufficiently low levels of noise for a given security level. We conclude by examining how secret key expansion from covert communication can be performed in a computational security model.

  5. 76 FR 70225 - Advisory Council to the Internal Revenue Service; Meeting

    Science.gov (United States)

    2011-11-10

    ... discussed include, but not limited to: Remote Work, Commercial Awareness, Schedule UTP, Distance Learning... people, IRSAC members and Internal Revenue Service officials inclusive. Due to limited seating, please...

  6. Official Time Usage in the Federal Government Fiscal Year 2005 Survey Responses

    Data.gov (United States)

    Office of Personnel Management — Section 7131 of title 5, United States Code, defines and authorizes official time for unions representing Federal employees. Official time, broadly defined, is paid...

  7. Pancreatic bicarbonate secretion involves two proton pumps

    DEFF Research Database (Denmark)

    Novak, Ivana; Wang, Jing; Henriksen, Katrine L.

    2011-01-01

    Pancreas secretes fluid rich in digestive enzymes and bicarbonate. The alkaline secretion is important in buffering of acid chyme entering duodenum and for activation of enzymes. This secretion is formed in pancreatic ducts, and studies to date show that plasma membranes of duct epithelium expres...

  8. Gastric secretion elicited by conditioning in rats.

    Science.gov (United States)

    Caboclo, José Liberato Ferreira; Cury, Francico de Assis; Borin, Aldenis Albanese; Caboclo, Luís Otávio Sales Ferreira; Ribeiro, Maria Fernanda Sales Caboclo; de Freitas, Pedro José; Andersson, Sven

    2009-01-01

    To investigate whether interdigestive gastric acid secretion can be controlled by a possible memory-related cortical mechanism. To evaluate gastric secretion in rats, we used a methodology that allows gastric juice collection in rats in their habitual conditions (without any restraining) by pairing sound as the conditioning stimulus (CS) and food as the unconditioning stimulus (US). The levels of gastric acid secretion under basal conditions and under sound stimulation were recorded and the circulating gastrin levels determined. When the gastric juice was collected in the course of the conditioning procedure, the results showed that under noise stimulation a significant increase in gastric acid secretion occurred after 10 days of conditioning (p<0.01). The significance was definitively demonstrated after 13 days of conditioning (p<0.001). Basal secretions of the conditioned rats reached a significant level after 16 days of conditioning. The levels of noise-stimulated gastric acid secretion were the highest so far described in physiological experiments carried out in rats and there were no significant increases in the circulating gastrin levels. The results point to the important role played by cortical structures in the control of interdigestive gastric acid secretion in rats. If this mechanism is also present in humans, it may be involved in diseases caused by inappropriate gastric acid secretion during the interprandial periods.

  9. School Library Services in a Multicultural Society

    Science.gov (United States)

    Montiel-Overall, Patricia, Ed.; Adcock, Donald C., Ed.

    2009-01-01

    According to the preface, "in light of the growing multicultural population in the United States, twenty-first-century library services will require culturally competent librarians." For years AASL has been addressing cultural issues in its official journal, "Knowledge Quest". This collection brings together articles that touch…

  10. 20 CFR 405.360 - Official record.

    Science.gov (United States)

    2010-04-01

    ... in making the decision under review and any additional evidence or written statements that the... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Official record. 405.360 Section 405.360 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW PROCESS FOR ADJUDICATING INITIAL...

  11. 21 CFR 20.61 - Trade secrets and commercial or financial information which is privileged or confidential.

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Exemptions § 20.61 Trade..., preparing, compounding, or processing of trade commodities and that can be said to be the end product of either innovation or substantial effort. There must be a direct relationship between the trade secret and...

  12. The School Business Official: Ten Habits You'll Need To Succeed.

    Science.gov (United States)

    Giambrone, William, Jr.

    2001-01-01

    Describes 10 habits school business officials need to succeed: organization, time management, delegation, planning, collaboration, personal development, creativity, empathy, ethos, and leadership. Based on book "The School Business Official: Ten Habits You'll Need To Succeed," published by the Pennsylvania Association of School Business…

  13. 7 CFR 1940.316 - Responsible officials for the environmental review process.

    Science.gov (United States)

    2010-01-01

    ... submitted to the approval official for final determinations. The SEC will review the assessment and provide... adequacy of the assessment or the recommendations reached, the State Director, whether or not the approving... Law 103-354 official responsible for executing the environmental impact determination and...

  14. Air Force UAV’s: The Secret History

    Science.gov (United States)

    2010-07-01

    iA Mitchell Institute Study i Air Force UAVs The Secret History A Mitchell Institute Study July 2010 By Thomas P. Ehrhard Report Documentation Page...DATES COVERED 00-00-2010 to 00-00-2010 4. TITLE AND SUBTITLE Air Force UAVs The Secret History 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c... The Secret History 2 Air Force UAVs: The Secret History2 air Force uaVs: The secret history Has any airplane in the past decade captured the public

  15. A quantum secret-sharing protocol with fairness

    International Nuclear Information System (INIS)

    Liu, Feng; Qin, Su-Juan; Wen, Qiao-Yan

    2014-01-01

    A quantum secret-sharing (QSS) protocol consists of two main phases, called sharing and reconstruction. In the first phase, the dealer selects a secret, divides it into several shares, and sends each participant its share securely with a quantum channel. In the second phase, the participants run an interactive protocol in order to reconstruct the secret. If the participants can communicate via a broadcast channel, they can show their shares and learn the secrets simultaneously. So what happens if the channel is not simultaneous? In this paper, we propose a QSS protocol with cheaters by using partially and maximally entangled states. A secure and fair reconstruction mechanism is designed, in a way that each participant can learn or cannot learn the secret simultaneously. (papers)

  16. 9 CFR 121.9 - Responsible official.

    Science.gov (United States)

    2010-01-01

    ...) The responsible official must report the identification and final disposition of any select agent or toxin contained in a specimen presented for diagnosis or verification. (1) The identification of any of... virus, foot-and-mouth disease virus, Hendra virus, virulent Newcastle disease virus, Nipah virus, Rift...

  17. 16 CFR 5.59 - Presiding official.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Presiding official. 5.59 Section 5.59 Commercial Practices FEDERAL TRADE COMMISSION ORGANIZATION, PROCEDURES AND RULES OF PRACTICE STANDARDS OF... Chief Administrative Law Judge, who shall appoint an Administrative Law Judge to preside over the...

  18. 15 CFR 700.6 - Official actions.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Official actions. 700.6 Section 700.6 Commerce and Foreign Trade Regulations Relating to Commerce and Foreign Trade (Continued) BUREAU OF INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE NATIONAL SECURITY INDUSTRIAL BASE REGULATIONS DEFENSE...

  19. 22 CFR 208.885 - May the debarring official extend a debarment?

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false May the debarring official extend a debarment? 208.885 Section 208.885 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT GOVERNMENTWIDE... determines that an extension is necessary to protect the public interest. (b) However, the debarring official...

  20. The Observation of Bahasa Indonesia Official Computer Terms Implementation in Scientific Publication

    Science.gov (United States)

    Gunawan, D.; Amalia, A.; Lydia, M. S.; Muthaqin, M. I.

    2018-03-01

    The government of the Republic of Indonesia had issued a regulation to substitute computer terms in foreign language that have been used earlier into official computer terms in Bahasa Indonesia. This regulation was stipulated in Presidential Decree No. 2 of 2001 concerning the introduction of official computer terms in Bahasa Indonesia (known as Senarai Padanan Istilah/SPI). After sixteen years, people of Indonesia, particularly for academics, should have implemented the official computer terms in their official publications. This observation is conducted to discover the implementation of official computer terms usage in scientific publications which are written in Bahasa Indonesia. The data source used in this observation are the publications by the academics, particularly in computer science field. The method used in the observation is divided into four stages. The first stage is metadata harvesting by using Open Archive Initiative - Protocol for Metadata Harvesting (OAI-PMH). Second, converting the harvested document (in pdf format) to plain text. The third stage is text-preprocessing as the preparation of string matching. Then the final stage is searching the official computer terms based on 629 SPI terms by using Boyer-Moore algorithm. We observed that there are 240,781 foreign computer terms in 1,156 scientific publications from six universities. This result shows that the foreign computer terms are still widely used by the academics.

  1. Using Virtualization and Automatic Evaluation: Adapting Network Services Management Courses to the EHEA

    Science.gov (United States)

    Ros, S.; Robles-Gomez, A.; Hernandez, R.; Caminero, A. C.; Pastor, R.

    2012-01-01

    This paper outlines the adaptation of a course on the management of network services in operating systems, called NetServicesOS, to the context of the new European Higher Education Area (EHEA). NetServicesOS is a mandatory course in one of the official graduate programs in the Faculty of Computer Science at the Universidad Nacional de Educacion a…

  2. Civil Liability for Nuclear Damage. Official Records

    International Nuclear Information System (INIS)

    1964-01-01

    These Official Records of the Conference contain the summary records of the plenary meetings and of the meetings of the Committee of the Whole, the text of the Convention, the Optional Protocol, the Final Act, the resolutions adopted by the Conference and the reports of the committees and sub-committees, as well as all other documents which were submitted to the plenary and the Committee of the Whole. These Official Records also contain a complete index of documents relevant to each Article of the Convention according to its number in the final text. The history of the preparatory studies and documents is summarized on pages 39, 40 and 65-86. The symbols of International Atomic Energy Agency documents are composed of capital letters combined with figures. Mention of such a symbol indicates a reference to an International Atomic Energy Agency document. The summary records of the plenary meetings and of the meetings of the Committee of the Whole contained in this volume were originally circulated in mimeographed form as documents CN-12/OR/1 to 7 and CN-12, CW/OR. 1 to 24 respectively. As printed in this volume they include the corrections to the provisional summary records that were requested by the delegations and such drafting and editorial changes as were considered necessary. These official records are available in English, French, Russian and Spanish. (author)

  3. Sustainable procurement of official cars for the Dutch government

    International Nuclear Information System (INIS)

    Notenboom, M.

    2009-04-01

    The objectives of this study are to develop more strict sustainability criteria for procurement policy for official cars for the Dutch government, to examine the effects of alternative scenarios and to provide recommendations that can be used by the Netherlands Society for Nature and Environment to stimulate the government in using more ambitious criteria in their latest tender for official cars. These recommendations involve both the government?s choice of vehicles and the government?s use of these vehicles. [nl

  4. Contribution to the Study of the State Transport Service in Roman Administration

    Directory of Open Access Journals (Sweden)

    Raquel Escutia-Romero

    2017-01-01

    Full Text Available The cursus publicus was the government transportation system in the Roman Empire. It made government communication, travel by government officials and the transport of certain State goods such as tax money, metals (gold and silver and army equipment possible. This work seeks to illustrate the origin of this official service, the highways used, the infrastructure (mansiones and mutationes, the animals and wagons exchanged periodically along the way, the authorization for the use of cursus publicus administration, the extremely restricted issue of warrants for the use of the cursus publicus (evectiones, the funding of services and the irregularities and abuse of the system and the necessary legislation to avoid and condemn such acts.

  5. 18 CFR 385.2010 - Service (Rule 2010).

    Science.gov (United States)

    2010-04-01

    ... under law. (2) If any person receives a rejection letter or deficiency letter from the Commission, the... not become available in eLibrary within two business days after the document is filed, the person.... Name (if applicable) Address Telephone No. (k) Designation of corporate officials to receive service...

  6. Paralympic medical services for the 2010 paralympic winter games.

    Science.gov (United States)

    Taunton, Jack; Wilkinson, Michael; Celebrini, Rick; Stewart, Robert; Stasyniuk, Treny; Van de Vliet, Peter; Willick, Stuart; Ferrer, Josep Martinez

    2012-01-01

    To present the planning and medical encounters for the 2010 Paralympic Winter Games. Prospective medical encounter study. 2010 Paralympic Winter Games. Athletes, coaches, officials, workforce, volunteers, and media. Sport type: alpine, Nordic, and sledge hockey and curling. Participant type: athlete, workforce, and spectators. Terrain and speed. Medical encounters entered in database at competitive (alpine skiing, biathlon, cross-country skiing, sledge hockey, and curling) and noncompetitive (Whistler and Vancouver Polyclinics, presentation centers, opening and closing ceremonies, media center, Paralympic Family Hotel) venues. Forty-two nations participated with 1350 Paralympic athletes, coaches, and officials. There were 2590 accredited medical encounters (657 athletes, 25.4%; 682 International Federation/National Paralympic Committee officials, 26.3%; 57 IPC, 2.2%; 8 media, 0.3%; 1075 workforce, 41.5%; 111 others, 4.3%) and 127 spectator encounters for a total of 2717 encounters. During the preopening period medical services saw 201 accredited personnel. The busiest venues during the Paralympic Games were the Whistler (1633 encounters) and Vancouver (748 encounters) Polyclinics. Alpine, sledge hockey, and curling were the busiest competitive venues. The majority of medical encounters were musculoskeletal (44.6%, n = 1156). Medical services recorded 1657 therapy treatments, 977 pharmaceutical prescriptions dispensed, 204 dental treatments, 353 imaging examinations (more than 50% from alpine skiing), and 390 laboratory tests. There were 24 ambulance transfers with 7 inpatient hospitalizations for a total of 24 inpatient days and 4 outpatient visits. The mandate to have minimal impact on the health services of Vancouver and the Olympic Corridor while offering excellent medical services to the Games was accomplished. This data will be valuable to future organizing committees.

  7. Trade secrets protection mode of nuclear power plant

    International Nuclear Information System (INIS)

    Zeng Bin

    2015-01-01

    The paper analyzes the legal environment in which nuclear power enterprises are stayed, and mainly discusses the business secret protection modes of China's nuclear power enterprises. It is expected to provide a revelation and help for these enterprises to protect their business secrets. Firstly, the paper briefly expounds the legal basis of business secret protection and China's legalization status in this regard. Then it mainly puts forward the business secret management framework and postulations for nuclear power enterprises, and key points in application and protection of nuclear power business secret. (author)

  8. 31 CFR 515.337 - Prohibited officials of the Government of Cuba.

    Science.gov (United States)

    2010-07-01

    ... Government of Cuba. 515.337 Section 515.337 Money and Finance: Treasury Regulations Relating to Money and... REGULATIONS General Definitions § 515.337 Prohibited officials of the Government of Cuba. For purposes of this part, the term prohibited officials of the Government of Cuba means Ministers and Vice-ministers...

  9. Official Bilingualism and Field Narratives: Does School Practice Echo Policy Discourse?

    Science.gov (United States)

    Nana, Genevoix

    2013-01-01

    This research builds on several layers of meaning representing views from education officials, head teachers, teachers and pupils to investigate the discourse and implementation of official bilingualism policy in primary schools in Cameroon. While at the macro-level, the celebration of the "National Bilingualism Day" in schools has…

  10. 16 CFR 1502.33 - Official notice.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Official notice. 1502.33 Section 1502.33 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FEDERAL HAZARDOUS SUBSTANCES ACT REGULATIONS... notice may be taken of such matters as might be judicially noticed by the courts of the United States or...

  11. Automation of Publications in Official Statistics using R

    Directory of Open Access Journals (Sweden)

    Guido Schulz

    2018-03-01

    Full Text Available A key task of official statistical authorities is to collect and disseminate indicators periodically. Automation using a wide range of R packages bears massive potential to cut down the resources necessary for the creation of publications. Furthermore, automation in R has the potential to improve transparency, punctuality and coherence of statistical products. The dynamic reporting engine knitr in particular allows for an efficient combination of R’s functionalities of data retrieval, data manipulation and customizable plotting on the one hand, and the layout and typesetting flexibility of LaTex or other markup languages on the other. This allows official statistical authorities to produce either ready-to-print PDFs or interactive websites while adhering to their corporate design requirements. Furthermore, dynamic reporting makes it possible to update periodic publications automatically. A work in progress example of automated statistical country profiles – a product the German Federal Statistical Office regularly publishes based on a wide range of official international sources – will be presented to illustrate both advantages and challenges in the practical use of dynamic reporting using R and knitr in particular.

  12. 22 CFR 72.31 - Fees for consular death and estates services.

    Science.gov (United States)

    2010-04-01

    ... personal estates of all officers and employees of the United States who die abroad while on official duty... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Fees for consular death and estates services... PROPERTY AND ESTATES DEATHS AND ESTATES Fees § 72.31 Fees for consular death and estates services. (a) Fees...

  13. Modelling a web service approach to secure data access ...

    African Journals Online (AJOL)

    ... and timely means to transmit official information in every working environment. ... The 3-tier architecture adopted in this work would have the front-end to allow officers log in ... At the middle-end, users are authenticated for specific services.

  14. Study on provenance of Ru porcelain in yanhedian kiln and official jun porcelain by EDXRF

    International Nuclear Information System (INIS)

    Li Guoxia; Guo Min; Zhao Weijuan; Sun Hongwei; Gao Zhengyao; Xie Jianzhong; Wen Chang; Wang Chuan; Li Rongwu; Guo Peiyu; Yang Dawei

    2010-01-01

    To understand the provenance relationship of Ru porcelain in Yanhedian kiln and official Jun porcelain , with energy dispersive x-ray fluorescence spectrometer (EDXRF) measured 56 Ru porcelain in Yanhedian kiln and official Jun porcelain samples of chemical composition of the main volume, analysis results show: Yanhedian kiln Ru porcelain bodies Al 2 O 3 average content Outpaces official Jun porcelain bodies, SiO 2 , K 2 O average below official Jun porcelain bodies; Yanhedian kiln Ru porcelain glazes Al 2 O 3 average content Outpaces official Jun porcelain glaze, SiO 2 , CaO average significantly lower than Jun glaze, two primary body and glaze on porcelain to chemical composition of the averages vary. A display of the peacekeeping two-dimensional scatter analysis supplies of official Jun porcelain bodies focused, Yanhedia kiln Ru porcelain bodies birth supplies comparatively, Jun and Yanhedian kiln Ru porcelain bodies material habitats near but not identical. The official Jun porcelain glazes origin focused, glaze formula changes less, and Yanhedia kiln Ru porcelain glazes origin and formula are scattered. Therefore, Yanhedian kiln Ru porcelain samples and the Official Jun porcelain samples can be commendably differentiated by EDXRF testing and chemical composition scatter analysis. (authors)

  15. 22 CFR 92.8 - Compliance with request for notarial services.

    Science.gov (United States)

    2010-04-01

    ... care to prevent the use of his official seal in furthering any unlawful or clearly improper purpose. (See § 92.9 regarding refusal to perform notarial services in certain cases.) [22 FR 10858, Dec. 27...

  16. 9 CFR 316.8 - Unmarked inspected products; moved between official establishments; moved in commerce.

    Science.gov (United States)

    2010-01-01

    ... between official establishments; moved in commerce. 316.8 Section 316.8 Animals and Animal Products FOOD... establishment to another official establishment, for further processing, in a railroad car, truck, or other closed container, if the railroad car, truck, or container is sealed with an official seal of the...

  17. Problems of the current law concerning official plan approval

    International Nuclear Information System (INIS)

    Bluemel, W.

    1986-01-01

    The booklet presents lectures held in October 1985 at the Speyer University for Administration Science, on the subject of the law concerning official plan approval. The lectures have been selected for their common interest in the requirements of nature conservation and landscape protection. These requirements and the current practice of plan approval procedure are the main issue of the lectures which discuss aspects of environmental impact statements, consideration of ecological requirements, and the role of the landscape conservation plan accompanying official project planning documents. (HSCH) [de

  18. Regulation of glucagon secretion by incretins

    DEFF Research Database (Denmark)

    Holst, Jens Juul; Christensen, M; Lund, A

    2011-01-01

    Glucagon secretion plays an essential role in the regulation of hepatic glucose production, and elevated fasting and postprandial plasma glucagon concentrations in patients with type 2 diabetes (T2DM) contribute to their hyperglycaemia. The reason for the hyperglucagonaemia is unclear, but recent...... studies have shown lack of suppression after oral but preserved suppression after isoglycaemic intravenous glucose, pointing to factors from the gut. Gastrointestinal hormones that are secreted in response to oral glucose include glucagon-like peptide-1 (GLP-1) that strongly inhibits glucagon secretion......, and GLP-2 and GIP, both of which stimulate secretion. When the three hormones are given together on top of isoglycaemic intravenous glucose, glucagon suppression is delayed in a manner similar to that observed after oral glucose. Studies with the GLP-1 receptor antagonist, exendin 9-39, suggest...

  19. Tax administration as health policy: hospitals, the Internal Revenue Service, and the courts.

    Science.gov (United States)

    Fox, D M; Schaffer, D C

    1991-01-01

    Since 1969 federal tax policy has permitted nonprofit hospitals to turn away indigent patients or to transfer them to public hospitals. The Internal Revenue Service made health policy, but its officials remain convinced that they were not making policy at all. Convinced that it was reasoning from legal principles, the Revenue Service accepted the hospital industry's view of the history and purpose of hospitals. The federal courts further obscured the problem. Moreover, the Revenue Service took no interest in the effects of its ruling on the services provided by tax-exempt hospitals until 1989. We describe these events and seek to explain them by linking the recent history of health policy to the assumptions that govern the making of tax policy. We conclude that the making of health policy by tax officials who are not accountable for it and who believe that they are not making policy at all is not in the public interest.

  20. 28 CFR 540.22 - Special postal services.

    Science.gov (United States)

    2010-07-01

    ... 540.22 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT...) In the event of loss or damage, any claim relative to this matter is made to the U.S. Postal Service... example, hobbycraft articles mailed out of the institution). Official mail is not insured. If such an item...

  1. Role of adipose secreted factors and kisspeptin in the metabolic control of gonadotropin secretion and puberty

    Science.gov (United States)

    Factors secreted by adipose tissue continue to be discovered. Evidence indicates a strong link between neural influences and adipocyte expression and secretion of a wide array of cytokines, neurotrophic factors, growth factors, binding proteins, and neuropeptides. These “adipokines” are linked to im...

  2. Analysis of twitter users' sharing of official new york storm response messages.

    Science.gov (United States)

    Genes, Nicholas; Chary, Michael; Chason, Kevin

    2014-01-01

    Twitter is a social network where users read, send, and share snippets of text ("tweets"). Tweets can be disseminated through multiple means; on desktop computers, laptops, and mobile devices, over ethernet, Wi-Fi or cellular networks. This redundancy positions Twitter as a useful tool for disseminating information to the public during emergencies or disasters. Previous research on dissemination of information using Twitter has mostly investigated the characteristics of tweets that are most effective in raising consumer awareness about a new product or event. In particular, they describe characteristics that increase the chance the messages will be shared ("retweeted") by users. In comparison, little has been published on how information from municipal or state government agencies spreads on Twitter during emergency situations. Retweeting these messages is a way to enhance public awareness of potentially important instructions from public officials in a disaster. The aim of this study is to (1) describe the tweets of select New York State and New York City agencies by public officials surrounding two notable recent winter storms that required a large-scale emergency response, and (2) identify the characteristics of the tweets of public officials that were most disseminated (retweeted). For one week surrounding Superstorm Sandy (October 2012) and the winter blizzard Nemo (February 2013), we collected (1) tweets from the official accounts for six New York governmental agencies, and (2) all tweets containing the hashtags #sandy (or #nemo) and #nyc. From these data we calculated how many times a tweet was retweeted, controlling for differences in baseline activity in each account. We observed how many hashtags and links each tweet contained. We also calculated the lexical diversity of each tweet, a measure of the range of vocabulary used. During the Sandy storm, 3242 shared (retweeted) messages from public officials were collected. The lexical diversity of official

  3. Burkholderia cenocepacia type VI secretion system mediates escape of type II secreted proteins into the cytoplasm of infected macrophages.

    Directory of Open Access Journals (Sweden)

    Roberto Rosales-Reyes

    Full Text Available Burkholderia cenocepacia is an opportunistic pathogen that survives intracellularly in macrophages and causes serious respiratory infections in patients with cystic fibrosis. We have previously shown that bacterial survival occurs in bacteria-containing membrane vacuoles (BcCVs resembling arrested autophagosomes. Intracellular bacteria stimulate IL-1β secretion in a caspase-1-dependent manner and induce dramatic changes to the actin cytoskeleton and the assembly of the NADPH oxidase complex onto the BcCV membrane. A Type 6 secretion system (T6SS is required for these phenotypes but surprisingly it is not required for the maturation arrest of the BcCV. Here, we show that macrophages infected with B. cenocepacia employ the NLRP3 inflammasome to induce IL-1β secretion and pyroptosis. Moreover, IL-1β secretion by B. cenocepacia-infected macrophages is suppressed in deletion mutants unable to produce functional Type VI, Type IV, and Type 2 secretion systems (SS. We provide evidence that the T6SS mediates the disruption of the BcCV membrane, which allows the escape of proteins secreted by the T2SS into the macrophage cytoplasm. This was demonstrated by the activity of fusion derivatives of the T2SS-secreted metalloproteases ZmpA and ZmpB with adenylcyclase. Supporting this notion, ZmpA and ZmpB are required for efficient IL-1β secretion in a T6SS dependent manner. ZmpA and ZmpB are also required for the maturation arrest of the BcCVs and bacterial intra-macrophage survival in a T6SS-independent fashion. Our results uncover a novel mechanism for inflammasome activation that involves cooperation between two bacterial secretory pathways, and an unanticipated role for T2SS-secreted proteins in intracellular bacterial survival.

  4. Role definition among public officials and emergency workers in a nuclear evacuation

    International Nuclear Information System (INIS)

    Metz, W.C.

    1983-01-01

    How public officials and emergency workers will resolve conflict between their official duties and assigned tasks and their family and conscience responsibilities is discussed in the context of the Indian Point nuclear station, and the Shoreham nuclear station

  5. LEP Celebration : the official programme

    CERN Multimedia

    CERN. Geneva

    2000-10-09

    At 14:00: Groupe de Jazz "Wolfgang & The Werewolves" . The official programme begins at 15:00 with an introduction from the Director General, and Professor Martinus Veltman will give the keynote speech. Heads of national delegations represented at ministerial level will then make their speeches, following which a commemorative plaque will be unveiled. A specially commissioned ballet by Maurice Béjart will bring the ceremony to a close.

  6. Visualization of glucagon secretion from pancreatic α cells by bioluminescence video microscopy: Identification of secretion sites in the intercellular contact regions

    International Nuclear Information System (INIS)

    Yokawa, Satoru; Suzuki, Takahiro; Inouye, Satoshi; Inoh, Yoshikazu; Suzuki, Ryo; Kanamori, Takao; Furuno, Tadahide; Hirashima, Naohide

    2017-01-01

    We have firstly visualized glucagon secretion using a method of video-rate bioluminescence imaging. The fusion protein of proglucagon and Gaussia luciferase (PGCG-GLase) was used as a reporter to detect glucagon secretion and was efficiently expressed in mouse pancreatic α cells (αTC1.6) using a preferred human codon-optimized gene. In the culture medium of the cells expressing PGCG-GLase, luminescence activity determined with a luminometer was increased with low glucose stimulation and KCl-induced depolarization, as observed for glucagon secretion. From immunochemical analyses, PGCG-GLase stably expressed in clonal αTC1.6 cells was correctly processed and released by secretory granules. Luminescence signals of the secreted PGCG-GLase from the stable cells were visualized by video-rate bioluminescence microscopy. The video images showed an increase in glucagon secretion from clustered cells in response to stimulation by KCl. The secretory events were observed frequently at the intercellular contact regions. Thus, the localization and frequency of glucagon secretion might be regulated by cell-cell adhesion. - Highlights: • The fused protein of proglucagon to Gaussia luciferase was used as a reporter. • The fusion protein was highly expressed using a preferred human-codon optimized gene. • Glucagon secretion stimulated by depolarization was determined by luminescence. • Glucagon secretion in α cells was visualized by bioluminescence imaging. • Glucagon secretion sites were localized in the intercellular contact regions.

  7. 29 CFR 1903.9 - Trade secrets.

    Science.gov (United States)

    2010-07-01

    ... INSPECTIONS, CITATIONS AND PROPOSED PENALTIES § 1903.9 Trade secrets. (a) Section 15 of the Act provides: “All... concerns or relates to the trade secrets, processes, operations, style of work, or apparatus, or to the...

  8. Air Force UAVs: The Secret History

    Science.gov (United States)

    2010-07-01

    iA Mitchell Institute Study i Air Force UAVs The Secret History A Mitchell Institute Study July 2010 By Thomas P. Ehrhard Report Documentation Page...DATES COVERED 00-00-2010 to 00-00-2010 4. TITLE AND SUBTITLE Air Force UAVs The Secret History 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c...opening phases of Operation Enduring Freedom in Afghanistan. By Thomas P. Ehrhard a miTchEll insTiTuTE sTudy July 2010 Air Force UAVs The Secret History

  9. Official portrait of astronaut Ronald J. Grabe

    Science.gov (United States)

    1989-01-01

    Official portrait of Ronald J. Grabe, United States Air Force (USAF) Colonel, member of Astronaut Class 9 (1980), and space shuttle pilot. Grabe wears launch and entry suit (LES) with helmet displayed on table at his left.

  10. THE BUFFER CAPACITY OF AIRWAY EPITHELIAL SECRETIONS

    Directory of Open Access Journals (Sweden)

    Dusik eKim

    2014-06-01

    Full Text Available The pH of airway epithelial secretions influences bacterial killing and mucus properties and is reduced by acidic pollutants, gastric reflux, and respiratory diseases such as cystic fibrosis (CF. The effect of acute acid loads depends on buffer capacity, however the buffering of airway secretions has not been well characterized. In this work we develop a method for titrating micro-scale (30 µl volumes and use it to study fluid secreted by the human airway epithelial cell line Calu-3, a widely used model for submucosal gland serous cells. Microtitration curves revealed that HCO3- is the major buffer. Peak buffer capacity (β increased from 17 to 28 mM/pH during forskolin stimulation, and was reduced by >50% in fluid secreted by cystic fibrosis transmembrane conductance regulator (CFTR-deficient Calu-3 monolayers, confirming an important role of CFTR in HCO3- secretion. Back-titration with NaOH revealed non-volatile buffer capacity due to proteins synthesized and released by the epithelial cells. Lysozyme and mucin concentrations were too low to buffer Calu-3 fluid significantly, however model titrations of porcine gastric mucins at concentrations near the sol-gel transition suggest that mucins may contribute to the buffer capacity of ASL in vivo. We conclude that CFTR-dependent HCO3- secretion and epithelially-derived proteins are the predominant buffers in Calu-3 secretions.

  11. The ESX system in Bacillus subtilis mediates protein secretion.

    Directory of Open Access Journals (Sweden)

    Laura A Huppert

    Full Text Available Esat-6 protein secretion systems (ESX or Ess are required for the virulence of several human pathogens, most notably Mycobacterium tuberculosis and Staphylococcus aureus. These secretion systems are defined by a conserved FtsK/SpoIIIE family ATPase and one or more WXG100 family secreted substrates. Gene clusters coding for ESX systems have been identified amongst many organisms including the highly tractable model system, Bacillus subtilis. In this study, we demonstrate that the B. subtilis yuk/yue locus codes for a nonessential ESX secretion system. We develop a functional secretion assay to demonstrate that each of the locus gene products is specifically required for secretion of the WXG100 virulence factor homolog, YukE. We then employ an unbiased approach to search for additional secreted substrates. By quantitative profiling of culture supernatants, we find that YukE may be the sole substrate that depends on the FtsK/SpoIIIE family ATPase for secretion. We discuss potential functional implications for secretion of a unique substrate.

  12. Using The Official Lamaze Guide in Childbirth Education Classes

    Science.gov (United States)

    Hotelling, Barbara A.

    2006-01-01

    Normal birth has long been promoted by Lamaze International in its mission and vision statements and by the Lamaze Institute for Normal Birth. The Official Lamaze Guide: Giving Birth with Confidence, a book by Judith Lothian and Charlotte DeVries, can be used by birth educators to alter the focus from learning what to expect when one fears the worst to empowering women to understand that birth is usually a healthy, normal process. In this column, the author suggests ways in which childbirth educators can use The Official Lamaze Guide in their classes. PMID:17541460

  13. What is the value of official statistics and how do we communicate that value?

    Directory of Open Access Journals (Sweden)

    Tudorel ANDREI

    2014-09-01

    Full Text Available Einstein’s aphorism mentioned above wasn’t meant to colour the text, but we particularly believe it corresponds, in a way, to the topic we plan to introduce during the seminar. Consequently, paraphrasing it, the aphorism suggests a derived one which could read: “Not any statistics is official statistics and not any official statement that contains a numerical expression is statistics”. As to the above statements, the following question normally arises: “if not any statistics is official statistics, than what does official statistics mean and where does this brand, that represents a special value of statistics, come from?” On the other hand, if not any official statement, that contains a numerical expression on a certain economic or social phenomenon, is statistics, then what kind of meaning does it have?

  14. Beyond the technical: The role of emotion regulation in lacrosse officiating.

    Science.gov (United States)

    Friesen, Andrew P; Devonport, Tracey J; Lane, Andrew M

    2017-03-01

    Emotions can influence the performance of referees leading to a need to examine emotions experienced, and regulation strategies used by referees. The present study assessed emotions and emotion regulation strategies of 19 referees officiating at an Under-19 Lacrosse World Championship. Using survey methods and focus group interviews, officials responded to five questions: (a) What emotions were experienced? (b) What events elicited emotions? (c) How did lacrosse officials manage their own emotional states prior to, throughout, and following a competitive game? (d) How did officials manage others' emotional states? (e) What were the perceived consequences of these strategies? Results indicate that emotions fluctuated throughout the tournament as referees encountered intrapersonal and interpersonal emotion-eliciting events. These fluctuations are suggested to come from a progressively diminished capacity for emotion regulation. Participants used emotion regulation strategies that could be classified into Gross' (1999) families of emotion regulation strategies, often relying on suppression, emotion contagion, and preventative refereeing. Collectively, the results offer new insights into referee emotion regulation at international events.

  15. Official Naming in Hå, Klepp and Time

    Directory of Open Access Journals (Sweden)

    Inge Særheim

    2012-08-01

    Full Text Available Toponyms localize, reflect and give information about historical traditions and various phenomena in an area. They form part of the local heritage and culture. The relationship between place names, heritage and identity is often underlined in guidelines regarding official naming of streets and roads. In what way is heritage and local identity reflected in the road names of the three municipalities Hå, Klepp and Time (Southwest-Norway, and how is the special character of this area expressed in the names? More than half of the official road names in the three municipalities are either identical with a local toponym, or they consist of a word for ‘road’ and a local toponym (or an appellative describing the location. This shows that there is a strong commitment to base the official naming on local tradition and thus contribute to identity. Quite a few elements from the dialect, e.g. special pronunciation, grammatical forms or local words, appear in the names, especially in the road names from Hå, reflecting that the names are part of the local culture, and due to the fact that the dialect is unique. Consistency is a challenge, however; the same word is sometimes spelled in different ways in different names. It appears that, with some exceptions, cultural heritage and local tradition have been preferred principles and guidelines with regard to naming of roads in the three municipalities, due to a consciousness that heritage and tradition create identity.

  16. Extrafloral nectar secretion from wounds of Solanum dulcamara.

    Science.gov (United States)

    Lortzing, Tobias; Calf, Onno W; Böhlke, Marlene; Schwachtje, Jens; Kopka, Joachim; Geuß, Daniel; Kosanke, Susanne; van Dam, Nicole M; Steppuhn, Anke

    2016-04-25

    Plants usually close wounds rapidly to prevent infections and the loss of valuable resources such as assimilates(1). However, herbivore-inflicted wounds on the bittersweet nightshade Solanum dulcamara appear not to close completely and produce sugary wound secretions visible as droplets. Many plants across the plant kingdom secrete sugary nectar from extrafloral nectaries(2) to attract natural enemies of herbivores for indirect defence(3,4). As ants forage on wound edges of S. dulcamara in the field, we hypothesized that wound secretions are a form of extrafloral nectar (EFN). We show that, unlike EFN from known nectaries, wound secretions are neither associated with any specific structure nor restricted to certain locations. However, similar to EFN, they are jasmonate-inducible and the plant controls their chemical composition. Wound secretions are attractive for ants, and application of wound secretion mimics increases ant attraction and reduces herbivory on S. dulcamara plants in a natural population. In greenhouse experiments, we reveal that ants can defend S. dulcamara from two of its native herbivores, slugs and flea beetle larvae. Since nectar is defined by its ecological function as a sugary secretion involved in interactions with animals(5), such 'plant bleeding' could be a primitive mode of nectar secretion exemplifying an evolutionary origin of structured extrafloral nectaries.

  17. Incretin hormone secretion over the day

    DEFF Research Database (Denmark)

    Ahren, B; Carr, RD; Deacon, Carolyn F.

    2010-01-01

    The two incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are key factors in the regulation of islet function and glucose metabolism, and incretin-based therapy for type 2 diabetes has gained considerable interest during recent years. Regulat......The two incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) are key factors in the regulation of islet function and glucose metabolism, and incretin-based therapy for type 2 diabetes has gained considerable interest during recent years....... Regulation of incretin hormone secretion is less well characterized. The main stimulus for incretin hormone secretion is presence of nutrients in the intestinal lumen, and carbohydrate, fat as well as protein all have the capacity to stimulate GIP and GLP-1 secretion. More recently, it has been established...... that a diurnal regulation exists with incretin hormone secretion to an identical meal being greater when the meal is served in the morning compared to in the afternoon. Finally, whether incretin hormone secretion is altered in disease states is an area with, so far, controversial results in different studies...

  18. Exosome secretion affects social motility in Trypanosoma brucei.

    Directory of Open Access Journals (Sweden)

    Dror Eliaz

    2017-03-01

    Full Text Available Extracellular vesicles (EV secreted by pathogens function in a variety of biological processes. Here, we demonstrate that in the protozoan parasite Trypanosoma brucei, exosome secretion is induced by stress that affects trans-splicing. Following perturbations in biogenesis of spliced leader RNA, which donates its spliced leader (SL exon to all mRNAs, or after heat-shock, the SL RNA is exported to the cytoplasm and forms distinct granules, which are then secreted by exosomes. The exosomes are formed in multivesicular bodies (MVB utilizing the endosomal sorting complexes required for transport (ESCRT, through a mechanism similar to microRNA secretion in mammalian cells. Silencing of the ESCRT factor, Vps36, compromised exosome secretion but not the secretion of vesicles derived from nanotubes. The exosomes enter recipient trypanosome cells. Time-lapse microscopy demonstrated that cells secreting exosomes or purified intact exosomes affect social motility (SoMo. This study demonstrates that exosomes are delivered to trypanosome cells and can change their migration. Exosomes are used to transmit stress signals for communication between parasites.

  19. Reappraisal of bicarbonate secretion by the human oesophagus

    DEFF Research Database (Denmark)

    Mertz-Nielsen, A; Hillingsø, J; Bukhave, Klaus

    1997-01-01

    BACKGROUND AND AIMS: Administration of omeprazole to healthy volunteers was recently reported to increase proximal duodenal mucosalbicarbonate secretion. As human oesophagus also secretes bicarbonate, the hypothesis was tested that omeprazole may stimulate oesophagealbicarbonate secretion and thus......: The median rates (95% confidence intervals)of intrinsic oesophageal bicarbonate secretion, corrected for contaminating salivary and gastric bicarbonate, were 89 (33-150) and 121 (63-203)mumol/h/10 cm (p > 0.5) in omeprazole and ranitidine treated subjects respectively. Salivary and gastric bicarbonate...... be overestimated. As omeprazole and ranitidine did not affect bicarbonate secretion differently there was no evidence that omeprazole acts on icarbonate secretory cells in the oesophageal mucosa....

  20. Indomethacin decreases gastroduodenal mucosal bicarbonate secretion in humans

    DEFF Research Database (Denmark)

    Mertz-Nielsen, A; Hillingsø, Jens; Bukhave, K

    1995-01-01

    BACKGROUND: Cyclooxygenase inhibitors reduce mucosal bicarbonate secretion in the duodenum, but the evidence for their effect on bicarbonate secretion in the stomach remains controversial. We have, therefore, studied how indomethacin influences gastroduodenal bicarbonate secretion and luminal...... healthy volunteers. Bicarbonate and PGE2 were measured in the gastroduodenal effluents by back-titration and radioimmunoassay, respectively. RESULTS: Vagal stimulation and duodenal luminal acidification (0.1 M HCl; 20 ml; 5 min) increased gastroduodenal bicarbonate secretion (p ... markedly inhibited both basal and stimulated gastric and duodenal mucosal bicarbonate secretion, and this reduction was similar to the degree of cyclooxygenase inhibition estimated by the luminal release of PGE2 (p

  1. Official Union Time Tracking System Operational Data Store

    Data.gov (United States)

    Social Security Administration — Official Union Time Tracking System captures the reporting and accounting of the representational activity for all American Federation of Government Employees (AFGE)...

  2. The Use of Official Statistics in Self-Selection Bias Modeling

    Directory of Open Access Journals (Sweden)

    Dalla Valle Luciana

    2016-12-01

    Full Text Available Official statistics are a fundamental source of publicly available information that periodically provides a great amount of data on all major areas of citizens’ lives, such as economics, social development, education, and the environment. However, these extraordinary sources of information are often neglected, especially by business and industrial statisticians. In particular, data collected from small businesses, like small and medium-sized enterprizes (SMEs, are rarely integrated with official statistics data.

  3. SECURE VISUAL SECRET SHARING BASED ON DISCRETE WAVELET TRANSFORM

    Directory of Open Access Journals (Sweden)

    S. Jyothi Lekshmi

    2015-08-01

    Full Text Available Visual Cryptography Scheme (VCS is an encryption method to encode secret written materials. This method converts the secret written material into an image. Then encode this secret image into n shadow images called shares. For the recreation of the original secret, all or some selected subsets of shares are needed; individual shares are of no use on their own. The secret image can be recovered simply by selecting some subset of these n shares, makes transparencies of them and stacking on top of each other. Nowadays, the data security has an important role. The shares can be altered by an attacker. So providing security to the shares is important. This paper proposes a method of adding security to cryptographic shares. This method uses two dimensional discrete wavelet transform to hide visual secret shares. Then the hidden secrets are distributed among participants through the internet. All hidden shares are extracted to reconstruct the secret.

  4. On Secret Sharing with Nonlinear Product Reconstruction

    DEFF Research Database (Denmark)

    Cascudo Pueyo, Ignacio; Cramer, Ronald; Mirandola, Diego

    2015-01-01

    Multiplicative linear secret sharing is a fundamental notion in the area of secure multiparty computation and, since recently, in the area of two-party cryptography as well. In a nutshell, this notion guarantees that the product of two secrets is obtained as a linear function of the vector......-necessarily-linear “product reconstruction function.” Is the resulting notion equivalent to multiplicative linear secret sharing? We show the (perhaps somewhat counterintuitive) result that this relaxed notion is strictly more general. Concretely, fix a finite field ${\\mathbb F}_q$ as the base field over which linear secret...... sharing is considered. Then we show there exists an (exotic) linear secret sharing scheme with an unbounded number of players $n$ such that it has $t$-privacy with $t = \\Omega(n)$ and such that it does admit a product reconstruction function, yet this function is necessarily nonlinear. In addition, we...

  5. Reelin secreted by GABAergic neurons regulates glutamate receptor homeostasis.

    Directory of Open Access Journals (Sweden)

    Cecilia Gonzalez Campo

    Full Text Available BACKGROUND: Reelin is a large secreted protein of the extracellular matrix that has been proposed to participate to the etiology of schizophrenia. During development, reelin is crucial for the correct cytoarchitecture of laminated brain structures and is produced by a subset of neurons named Cajal-Retzius. After birth, most of these cells degenerate and reelin expression persists in postnatal and adult brain. The phenotype of neurons that bind secreted reelin and whether the continuous secretion of reelin is required for physiological functions at postnatal stages remain unknown. METHODOLOGY/PRINCIPAL FINDINGS: Combining immunocytochemical and pharmacological approaches, we first report that two distinct patterns of reelin expression are present in cultured hippocampal neurons. We show that in hippocampal cultures, reelin is secreted by GABAergic neurons displaying an intense reelin immunoreactivity (IR. We demonstrate that secreted reelin binds to receptors of the lipoprotein family on neurons with a punctate reelin IR. Secondly, using calcium imaging techniques, we examined the physiological consequences of reelin secretion blockade. Blocking protein secretion rapidly and reversibly changes the subunit composition of N-methyl-D-aspartate glutamate receptors (NMDARs to a predominance of NR2B-containing NMDARs. Addition of recombinant or endogenously secreted reelin rescues the effects of protein secretion blockade and reverts the fraction of NR2B-containing NMDARs to control levels. Therefore, the continuous secretion of reelin is necessary to control the subunit composition of NMDARs in hippocampal neurons. CONCLUSIONS/SIGNIFICANCE: Our data show that the heterogeneity of reelin immunoreactivity correlates with distinct functional populations: neurons synthesizing and secreting reelin and/or neurons binding reelin. Furthermore, we show that continuous reelin secretion is a strict requirement to maintain the composition of NMDARs. We propose

  6. Melatonin Secretion Pattern in Critically Ill Patients

    DEFF Research Database (Denmark)

    Boyko, Yuliya; Holst, René; Jennum, Poul

    2017-01-01

    effect of remifentanil on melatonin secretion. We found that the risk of atypical sleep compared to normal sleep was significantly lower (p REM) sleep was only observed during the nonsedation period. We found preserved diurnal pattern of melatonin...... secretion in these patients. Remifentanil did not affect melatonin secretion but was associated with lower risk of atypical sleep pattern. REM sleep was only registered during the period of nonsedation.......Critically ill patients have abnormal circadian and sleep homeostasis. This may be associated with higher morbidity and mortality. The aims of this pilot study were (1) to describe melatonin secretion in conscious critically ill mechanically ventilated patients and (2) to describe whether melatonin...

  7. Thymidine secretion by hybridoma and myeloma cells

    International Nuclear Information System (INIS)

    Spilsberg, Bjorn; Rise, Frode; Petersen, Dirk; Nissen-Meyer, Jon

    2006-01-01

    Secretion of thymidine appeared to be a common property of hybridoma and myeloma cells, but not of other cell types, which were tested. Of three hybridoma cell lines tested, all secreted thymidine in amounts resulting in the accumulation of thymidine to concentrations of 10-20 μM in the culture medium. Also three of five myeloma cell lines that were analyzed secrete thymidine, but none of the other cell types that were studied. Thymidine was purified to homogeneity (4 mg purified from 3 l of culture medium) and identified as such by nuclear magnetic resonance spectroscopy. The cells that secreted thymidine showed high resistance to the growth inhibitory effect of thymidine

  8. Feature article: adoption of an official ISEA glossary

    Energy Technology Data Exchange (ETDEWEB)

    Zartarian, Valerie; Bahadori, Tina; McKone, Thomas

    2004-09-15

    The International Society for Exposure Analysis (ISEA) and its Nomenclature Committee have been involved since the mid-1990s in an intermittent but ongoing effort to develop an official ISEA glossary. Several related activities have stimulated greater interest and discussion nationally and internationally on a common exposure language. Among these activities are a 1997 Journal of Exposure Analysis and Environmental Epidemiology feature article on exposure and dose definitions and a 1999-initiated project of the International Programme on Chemical Safety (IPCS) (WHO/ILO/UNEP) to confront terminology issues hindering harmonization in the area of exposure assessment. Recently the ISEA members voted in support of adopting the IPCS glossary as the official ISEA glossary, and the ISEA Executive Board agreed to accept this recommendation. In this feature article we (1) describe the process through which the ISEA adopted the IPCS glossary as the official ISEA glossary, (2) present the joint IPC S/ISEA glossary of terms and their definitions, and (3) discuss plans for how the glossary can be used by ISEA and updated over time by ISEA and IPCS. The glossary is intended to be a living document that reflects the latest usage and maintains international harmonization of exposure terminology that can be practically applied to improve communication in exposure and related fields.

  9. Analysis of Twitter Users’ Sharing of Official New York Storm Response Messages

    Science.gov (United States)

    Chary, Michael; Chason, Kevin

    2014-01-01

    Background Twitter is a social network where users read, send, and share snippets of text (“tweets”). Tweets can be disseminated through multiple means; on desktop computers, laptops, and mobile devices, over ethernet, Wi-Fi or cellular networks. This redundancy positions Twitter as a useful tool for disseminating information to the public during emergencies or disasters. Previous research on dissemination of information using Twitter has mostly investigated the characteristics of tweets that are most effective in raising consumer awareness about a new product or event. In particular, they describe characteristics that increase the chance the messages will be shared ("retweeted") by users. In comparison, little has been published on how information from municipal or state government agencies spreads on Twitter during emergency situations. Retweeting these messages is a way to enhance public awareness of potentially important instructions from public officials in a disaster. Objective The aim of this study is to (1) describe the tweets of select New York State and New York City agencies by public officials surrounding two notable recent winter storms that required a large-scale emergency response, and (2) identify the characteristics of the tweets of public officials that were most disseminated (retweeted). Methods For one week surrounding Superstorm Sandy (October 2012) and the winter blizzard Nemo (February 2013), we collected (1) tweets from the official accounts for six New York governmental agencies, and (2) all tweets containing the hashtags #sandy (or #nemo) and #nyc. From these data we calculated how many times a tweet was retweeted, controlling for differences in baseline activity in each account. We observed how many hashtags and links each tweet contained. We also calculated the lexical diversity of each tweet, a measure of the range of vocabulary used. Results During the Sandy storm, 3242 shared (retweeted) messages from public officials were

  10. Intermittent subglottic secretion drainage may cause tracheal damage in patients with few oropharyngeal secretions.

    Science.gov (United States)

    Suys, E; Nieboer, K; Stiers, W; De Regt, J; Huyghens, L; Spapen, H

    2013-12-01

    Injurious prolapse of tracheal mucosa into the suction port has been reported in up to 50% of intubated patients receiving continuous aspiration of subglottic secretions. We investigated whether similar injury could be inflicted by automated intermittent aspiration. Six consecutive patients, intubated with the Mallinckrodt TaperGuard Evac™ endotracheal tube, were studied. A flow sensor was placed between the vacuum regulating system and the mucus collector. Intermittent suctioning was performed at a pressure of -125 mmHg with a 25s interval and duration of 15s. After 24h, a CT scan of the tracheal region was performed. Excessive negative suction pressure, a fast drop in aspiration flow to zero, and important "swinging" movements of secretions in the evacuation line were observed in all patients. Oral instillation of antiseptic mouthwash restored normal aspiration flow and secretion mobility. CT imaging showed marked entrapment of tracheal mucosa into the suction port in all patients. In patients with few oropharyngeal secretions, automated intermittent subglottic aspiration may result in significant and potential harmful invagination of tracheal mucosa into the suction lumen. A critical amount of fluid must be present in the oropharynx to assure adequate and safe aspiration. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Sagnac secret sharing over telecom fiber networks.

    Science.gov (United States)

    Bogdanski, Jan; Ahrens, Johan; Bourennane, Mohamed

    2009-01-19

    We report the first Sagnac quantum secret sharing (in three-and four-party implementations) over 1550 nm single mode fiber (SMF) networks, using a single qubit protocol with phase encoding. Our secret sharing experiment has been based on a single qubit protocol, which has opened the door to practical secret sharing implementation over fiber telecom channels and in free-space. The previous quantum secret sharing proposals were based on multiparticle entangled states, difficult in the practical implementation and not scalable. Our experimental data in the three-party implementation show stable (in regards to birefringence drift) quantum secret sharing transmissions at the total Sagnac transmission loop distances of 55-75 km with the quantum bit error rates (QBER) of 2.3-2.4% for the mean photon number micro?= 0.1 and 1.7-2.1% for micro= 0.3. In the four-party case we have achieved quantum secret sharing transmissions at the total Sagnac transmission loop distances of 45-55 km with the quantum bit error rates (QBER) of 3.0-3.7% for the mean photon number micro= 0.1 and 1.8-3.0% for micro?= 0.3. The stability of quantum transmission has been achieved thanks to our new concept for compensation of SMF birefringence effects in Sagnac, based on a polarization control system and a polarization insensitive phase modulator. The measurement results have showed feasibility of quantum secret sharing over telecom fiber networks in Sagnac configuration, using standard fiber telecom components.

  12. Analysis of secreted proteins from Aspergillus flavus.

    Science.gov (United States)

    Medina, Martha L; Haynes, Paul A; Breci, Linda; Francisco, Wilson A

    2005-08-01

    MS/MS techniques in proteomics make possible the identification of proteins from organisms with little or no genome sequence information available. Peptide sequences are obtained from tandem mass spectra by matching peptide mass and fragmentation information to protein sequence information from related organisms, including unannotated genome sequence data. This peptide identification data can then be grouped and reconstructed into protein data. In this study, we have used this approach to study protein secretion by Aspergillus flavus, a filamentous fungus for which very little genome sequence information is available. A. flavus is capable of degrading the flavonoid rutin (quercetin 3-O-glycoside), as the only source of carbon via an extracellular enzyme system. In this continuing study, a proteomic analysis was used to identify secreted proteins from A. flavus when grown on rutin. The growth media glucose and potato dextrose were used to identify differentially expressed secreted proteins. The secreted proteins were analyzed by 1- and 2-DE and MS/MS. A total of 51 unique A. flavus secreted proteins were identified from the three growth conditions. Ten proteins were unique to rutin-, five to glucose- and one to potato dextrose-grown A. flavus. Sixteen secreted proteins were common to all three media. Fourteen identifications were of hypothetical proteins or proteins of unknown functions. To our knowledge, this is the first extensive proteomic study conducted to identify the secreted proteins from a filamentous fungus.

  13. Towards a New Digital Era: Observing Local E-Government Services Adoption in a Chinese Municipality

    Directory of Open Access Journals (Sweden)

    Yao Yang

    2017-09-01

    Full Text Available As electronic government services (e-government evolve, traditional applications such as online portals are encountering challenges in a new digital era in which people thirst for more convenient, diverse channels of communication with their government. Despite the efforts devoted to the promotion of Social Networking Service (SNS use in e-government for the past few years, empirical studies regarding this ongoing trend are still insufficient. In the local administration of China, a special collaboration between local governments and private Internet enterprises is happening: government services are imported into commercial SNS platforms known as WeChat and Weibo. This research conducts a case study of a Chinese municipality premised upon survey data (N = 605 collected in Chongqing. It examines the determinants of e-services adoption in four major local applications: two traditional government-led services “Government website portal” and “Government official app” (traditional government-led services, and two built-in government services on social networking applications “Weibo Government official account” “WeChat Public Services”. The paper aims to provide a closer understanding of current trends in local government e-services, or in this case, an innovative trial of Chinese e-government practices.

  14. Pituitary-hormone secretion by thyrotropinomas

    OpenAIRE

    Roelfsema, Ferdinand; Kok, Simon; Kok, Petra; Pereira, Alberto M.; Biermasz, Nienke R.; Smit, Jan W.; Frolich, Marijke; Keenan, Daniel M.; Veldhuis, Johannes D.; Romijn, Johannes A.

    2008-01-01

    Hormone secretion by somatotropinomas, corticotropinomas and prolactinomas exhibits increased pulse frequency, basal and pulsatile secretion, accompanied by greater disorderliness. Increased concentrations of growth hormone (GH) or prolactin (PRL) are observed in about 30% of thyrotropinomas leading to acromegaly or disturbed sexual functions beyond thyrotropin (TSH)-induced hyperthyroidism. Regulation of non-TSH pituitary hormones in this context is not well understood. We there therefore ev...

  15. Peptides and neurotransmitters that affect renin secretion

    Science.gov (United States)

    Ganong, W. F.; Porter, J. P.; Bahnson, T. D.; Said, S. I.

    1984-01-01

    Substance P inhibits renin secretion. This polypeptide is a transmitter in primary afferent neurons and is released from the peripheral as well as the central portions of these neurons. It is present in afferent nerves from the kidneys. Neuropeptide Y, which is a cotransmitter with norepinephrine and epinephrine, is found in sympathetic neurons that are closely associated with and presumably innervate the juxtagolmerular cells. Its effect on renin secretion is unknown, but it produces renal vasoconstriction and natriuresis. Vasoactive intestinal polypeptide (VIP) is a cotransmitter with acetylocholine in cholinergic neurons, and this polypeptide stimulates renin secretion. We cannot find any evidence for its occurence in neurons in the kidneys, but various stimuli increase plasma VIP to levels comparable to those produced by doses of exogenous VIP which stimulated renin secretion. Neostigmine increases plasma VIP and plasma renin activity, and the VIP appears to be responsible for the increase in renin secretion, since the increase is not blocked by renal denervation or propranolol. Stimulation of various areas in the brain produces sympathetically mediated increases in plasma renin activity associated with increases in blood pressure. However, there is pharmacological evidence that the renin response can be separated from the blood pressure response. In anaesthetized dogs, drugs that increase central serotonergic discharge increase renin secretion without increasing blood pressure. In rats, activation of sertonergic neurons in the dorsal raphe nucleus increases renin secretion by a pathway that projects from this nucleus to the ventral hypothalamus, and from there to the kidneys via the sympathetic nervous system. The serotonin releasing drug parachloramphetamine also increases plasma VIP, but VIP does not appear to be the primary mediator of the renin response. There is preliminary evidence that the serotonergic neurons in the dorsal raphe nucleus are part of the

  16. Will They or Won't They? Secret Telling in Interpersonal Interactions.

    Science.gov (United States)

    Kowalski, Robin Marie; Morgan, Chad Alan; Whittaker, Elizabeth; Zaremba, Brittany; Frazee, Laura; Dean, Jessica

    2015-01-01

    This study investigated predictors of within-gender secret telling. Eighty-eight participants were exposed to either a "positive" or a "negative" secret about another individual. Just under 20% of participants told the secret. Conscientiousness, secret condition, empathy, and the conscientiousness by secret condition interaction had effects on the rate of secret telling, χ(2) (5,82) = 17.78, p = .003, AIC = 80.60. Conscientiousness had a negative effect on secret telling among participants that told the "negative" secret.

  17. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Yunli, E-mail: chrisyu1255@yahoo.com.cn [Department of Pharmaceutics, The Second Affiliated Hospital of Soochow University, Suzhou 215004 (China); Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Wang, Xinting, E-mail: wxinting1986@yahoo.com.cn [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Liu, Can, E-mail: ltsan@163.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Yao, Dan, E-mail: erinyao@126.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Shanghai Institute of Materia Medica, Shanghai 201203 (China); Hu, Mengyue, E-mail: juliahmy@126.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Li, Jia, E-mail: ljbzd@163.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Hu, Nan, E-mail: hn_324@163.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Liu, Li, E-mail: liulee@cpu.edu.cn [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Liu, Xiaodong, E-mail: xdliu@cpu.edu.cn [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China)

    2013-02-01

    Accumulating evidences have showed that gatifloxacin causes dysglycemia in both diabetic and non-diabetic patients. Our preliminary study demonstrated that gatifloxacin stimulated glucagon-like peptide 1 (GLP-1) secretion from intestinal cells. The aim of the study was to investigate the association between gatifloxacin-stimulated GLP-1 release and dysglycemia in both normal and streptozotocin-induced diabetic rats and explore the possible mechanisms. Oral administration of gatifloxacin (100 mg/kg/day and 200 mg/kg/day) for 3 and 12 days led to marked elevation of GLP-1 levels, accompanied by significant decrease in insulin levels and increase in plasma glucose. Similar results were found in normal rats treated with 3-day gatifloxacin. Gatifloxacin-stimulated GLP-1 release was further confirmed in NCI-H716 cells, which was abolished by diazoxide, a K{sub ATP} channel opener. QT-PCR analysis showed that gatifloxacin also upregulated expression of proglucagon and prohormone convertase 3 mRNA. To clarify the contradiction on elevated GLP-1 without insulinotropic effect, effects of GLP-1 and gatifloxacin on insulin release were investigated using INS-1 cells. We found that short exposure (2 h) to GLP-1 stimulated insulin secretion and biosynthesis, whereas long exposure (24 h and 48 h) to high level of GLP-1 inhibited insulin secretion and biosynthesis. Moreover, we also confirmed gatifloxacin acutely stimulated insulin secretion while chronically inhibited insulin biosynthesis. All the results gave an inference that gatifloxacin stimulated over-secretion of GLP-1, in turn, high levels of GLP-1 and gatifloxacin synergistically impaired insulin release, worsening hyperglycemia. -- Highlights: ► Gatifloxacin induced hyperglycemia both in diabetic rats and normal rats. ► Gatifloxacin enhanced GLP-1 secretion but inhibited insulin secretion in rats. ► Long-term exposure to high GLP-1 inhibited insulin secretion and biosynthesis. ► GLP-1 over-secretion may be

  18. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats

    International Nuclear Information System (INIS)

    Yu, Yunli; Wang, Xinting; Liu, Can; Yao, Dan; Hu, Mengyue; Li, Jia; Hu, Nan; Liu, Li; Liu, Xiaodong

    2013-01-01

    Accumulating evidences have showed that gatifloxacin causes dysglycemia in both diabetic and non-diabetic patients. Our preliminary study demonstrated that gatifloxacin stimulated glucagon-like peptide 1 (GLP-1) secretion from intestinal cells. The aim of the study was to investigate the association between gatifloxacin-stimulated GLP-1 release and dysglycemia in both normal and streptozotocin-induced diabetic rats and explore the possible mechanisms. Oral administration of gatifloxacin (100 mg/kg/day and 200 mg/kg/day) for 3 and 12 days led to marked elevation of GLP-1 levels, accompanied by significant decrease in insulin levels and increase in plasma glucose. Similar results were found in normal rats treated with 3-day gatifloxacin. Gatifloxacin-stimulated GLP-1 release was further confirmed in NCI-H716 cells, which was abolished by diazoxide, a K ATP channel opener. QT-PCR analysis showed that gatifloxacin also upregulated expression of proglucagon and prohormone convertase 3 mRNA. To clarify the contradiction on elevated GLP-1 without insulinotropic effect, effects of GLP-1 and gatifloxacin on insulin release were investigated using INS-1 cells. We found that short exposure (2 h) to GLP-1 stimulated insulin secretion and biosynthesis, whereas long exposure (24 h and 48 h) to high level of GLP-1 inhibited insulin secretion and biosynthesis. Moreover, we also confirmed gatifloxacin acutely stimulated insulin secretion while chronically inhibited insulin biosynthesis. All the results gave an inference that gatifloxacin stimulated over-secretion of GLP-1, in turn, high levels of GLP-1 and gatifloxacin synergistically impaired insulin release, worsening hyperglycemia. -- Highlights: ► Gatifloxacin induced hyperglycemia both in diabetic rats and normal rats. ► Gatifloxacin enhanced GLP-1 secretion but inhibited insulin secretion in rats. ► Long-term exposure to high GLP-1 inhibited insulin secretion and biosynthesis. ► GLP-1 over-secretion may be involved in

  19. Shigella IpaD has a dual role: signal transduction from the type III secretion system needle tip and intracellular secretion regulation.

    Science.gov (United States)

    Roehrich, A Dorothea; Guillossou, Enora; Blocker, Ariel J; Martinez-Argudo, Isabel

    2013-02-01

    Type III secretion systems (T3SSs) are protein injection devices essential for the interaction of many Gram-negative bacteria with eukaryotic cells. While Shigella assembles its T3SS when the environmental conditions are appropriate for invasion, secretion is only activated after physical contact with a host cell. First, the translocators are secreted to form a pore in the host cell membrane, followed by effectors which manipulate the host cell. Secretion activation is tightly controlled by conserved T3SS components: the needle tip proteins IpaD and IpaB, the needle itself and the intracellular gatekeeper protein MxiC. To further characterize the role of IpaD during activation, we combined random mutagenesis with a genetic screen to identify ipaD mutant strains unable to respond to host cell contact. Class II mutants have an overall defect in secretion induction. They map to IpaD's C-terminal helix and likely affect activation signal generation or transmission. The Class I mutant secretes translocators prematurely and is specifically defective in IpaD secretion upon activation. A phenotypically equivalent mutant was found in mxiC. We show that IpaD and MxiC act in the same intracellular pathway. In summary, we demonstrate that IpaD has a dual role and acts at two distinct locations during secretion activation. © 2013 Blackwell Publishing Ltd.

  20. Histaminergic regulation of prolactin secretion

    DEFF Research Database (Denmark)

    Knigge, U P

    1990-01-01

    Histamine (HA), which acts as a neurotransmitter in the central nervous system, participates in the neuroendocrine regulation of prolactin (PRL) secretion. HA has a predominant stimulatory effect which is mediated via H2-receptors following central administration and via H1-receptors following...... systemic infusion of the amine. In addition, HA seems to exert a minor inhibitory effect on PRL secretion, an effect unmasked only during blockade of the receptor mediating the stimulatory effect. Following central administration the inhibitory effect is mediated via H1-receptors, while following systemic...... administration this effect is mediated via H2-receptors. In accordance with these findings, the H2-receptor antagonist cimetidine (CIM) has an inhibitory (following central administration) or stimulatory (following systemic administration) effect on PRL secretion. However, high doses of CIM possess an additional...

  1. 48 CFR 31.205-33 - Professional and consultant service costs.

    Science.gov (United States)

    2010-10-01

    ... contractor. Examples include those services acquired by contractors or subcontractors in order to enhance..., training, or direct assistance, such as studies, analyses, evaluations, liaison with Government officials..., or otherwise resulting in violation of any statute or regulation prohibiting improper business...

  2. An unexpected knock on Corrigan's secret door.

    Science.gov (United States)

    Woywodt, Alexander

    2010-10-01

    Corrigan's secret door describes a metaphorical escape route for busy physicians. The term was derived from the successful and exceptionally busy professional life of Irish physician Dominic John Corrigan (1802-80). It is claimed that Corrigan's outpatient clinic was so busy that he required a secret door in his consulting rooms to escape from the ever-growing queue of eager patients. The origins of this charming story are unknown, and the door may have never existed. However, at present, Corrigan's secret door is often quoted when busy physicians have their own little ways in surviving a stressful professional life. Generations of British-trained doctors have grown up with Corrigan's secret door, as it was featured in the introduction of the Oxford Handbook of Clinical Medicine. Accordingly, trainees as well as more senior doctors are often reminded that having a 'secret door' is vital in surviving in the medical profession. My own escape is through classical music and the violoncello, in particular. As the name implies, my own secret door is normally invisible to colleagues and patients. This little article is about a patient who found me out, and a reflection on the role of classical music and the cello in my professional life.

  3. Salinity Alters the Polyisoprenoid Alcohol Content and Composition of Both Salt-Secreting and Non–Salt-Secreting Mangrove Seedlings

    Directory of Open Access Journals (Sweden)

    Mohammad Basyuni

    2017-10-01

    Full Text Available The effects of salinity on the polyisoprenoid alcohol content and composition of the salt-secreting mangrove species Avicennia marina and Sonneratia alba and the non–salt-secreting species Bruguiera gymnorrhiza and Kandelia obovata were studied. The seedlings of mangroves were grown for 5 months under 0% and 3% salt concentrations. The occurrence, content, and distribution of four mangrove seedlings were analyzed by two-dimensional thin layer chromatography. The structural groups of the polyprenols and dolichols in the leaves and roots were classified into two types (I and II. In type I, dolichols predominated over polyprenols (more than 90%, whereas in type II, the occurrence of both polyprenols and dolichols was observed. Polyprenols were not detected in the leaves of A. marina and B. gymnorrhiza under 0% salt (control, but were detected in small amounts in K. obovata leaves; however, significant amounts were found in the 3% salinity group. This finding in A. marina, B. gymnorrhiza, and K. obovata leaves implies a change to the structural group: under 0% salt concentrations, the groups are classified as type I, but become type II under 3% salt concentrations. The occurrence of ficaprenol (C50–55 was found only in the leaves of the non–salt-secreting species B. gymnorrhiza and K. obovata under 3% salinity and not in the salt-secreting species A. marina or S. alba. It is noteworthy that the polyisoprenoid type in the roots of the four species showed no change under salinity; the two salt-secreting species A. marina and S. alba contained type I under 0% and 3% salt concentrations. On the other hand, type II polyisoprenoids were identified in the non–salt-secreting species B. gymnorrhiza and K. obovata under 0% and 3% salinity conditions. This finding suggested that polyisoprenoids play a protective role against salinity in the mangrove leaves of both salt-secreting and non–salt-secreting species.

  4. Secrets and Disclosures: How Young Children Handle Secrets

    Science.gov (United States)

    Anagnostaki, Lida; Wright, Michael J.; Papathanasiou, Athanasia

    2013-01-01

    The authors examined the influence of content and verbal cues on young children's understanding of secret information and of its disclosure. Participants were 209 5- and 6-year-old children in an experiment where a puppet, named Zinc, was the protagonist. Children were asked to whom Zinc would disclose a list of pieces of information, some of…

  5. Providing long-acting reversible contraception services in Seattle school-based health centers: key themes for facilitating implementation.

    Science.gov (United States)

    Gilmore, Kelly; Hoopes, Andrea J; Cady, Janet; Amies Oelschlager, Anne-Marie; Prager, Sarah; Vander Stoep, Ann

    2015-06-01

    The purpose of this study was to describe the implementation of a program that provides long-acting reversible contraception (LARC) services within school-based health centers (SBHCs) and to identify barriers and facilitators to implementation as reported by SBHC clinicians and administrators, public health officials, and community partners. We conducted 14 semistructured interviews with key informants involved in the implementation of LARC services. Key informants included SBHC clinicians and administrators, public health officials, and community partners. We used a content analysis approach to analyze interview transcripts for themes. We explored barriers to and facilitators of LARC service delivery across and within key informant groups. The most cited barriers across key informant groups were as follows: perceived lack of provider procedural skills and bias and negative attitudes about LARC methods. The most common facilitators identified across groups were as follows: clear communication strategies, contraceptive counseling practice changes, provider trainings, and stakeholder engagement. Two additional barriers emerged in specific key informant groups. Technical and logistical barriers to LARC service delivery were cited heavily by SBHC administrative staff, community partners, and public health officials. Expense and billing was a major barrier to SBHC administrative staff. LARC counseling and procedural services can be implemented in an SBHC setting to promote access to effective contraceptive options for adolescent women. Copyright © 2015 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  6. The American Military Advisor: Dealing with Senior Foreign Officials in the Islamic World

    National Research Council Canada - National Science Library

    Metrinko, Michael J

    2008-01-01

    "The American Military Advisor: Dealing with Senior Foreign Officials in the Islamic World" is a comprehensive guide for American military officers assigned as advisors to regional officials in places very different from the United States...

  7. Regulation of atrial natriuretic peptide (ANP) secretion

    International Nuclear Information System (INIS)

    Ruskoaho, H.; Toth, M.; Lang, R.E.; Unger, Th.; Garten, D.

    1986-01-01

    To investigate the role of calcium, protein kinase C and adenylate cyclase in the ANP secretion, the secretory responses from isolated perfused rat hearts to a calcium channel activator, Bay k8644 (methyl-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluomethylphenyl)-2-pyridine-5-carboxylate), the calcium ionophore (A23187), the phorbol ester (12-0-tetradecanoylphorbol-13-acetate, TPA), and to forskolin were studied. ANP in perfusate was measured by radioimmunoassay 10 min before and during the infusion (30 min) of various agents at 2 min intervals. A23187 (5.7 x 10 -7 ) induced a sharp increase, whereas TPA (0.15 - 1.6 x 10 -7 ) caused a slowly progressive increase in ANP secretion. 4a-phorbol-12,13-didecanoate, a non-active phorbol ester, had no effect on ANP secretion. Bay k8644 (4 x 10 -7 ) and forskolin (1 x 10 -6 ) alone caused small but sustained increase in ANP secretion. The combination of TPA with Bay k8644, forskolin or A23187 stimulated ANP secretion higher than the calculated additive value for each agent. Dibuturyl-cAMP (1.6 x 10 -4 ) pretreatment also enhanced TPA-induced ANP release. 8-Bromo-cGMP (1.3 x 10 -4 ) and sodium nitroprusside (9 x 10 -5 ) alone had no effect, but both attenuated the TPA-induced ANP secretion. The results suggest that atrial cardiocytes possess at least two different secretory pathways for ANP secretion, which are probably dependent on protein kinase C and cyclic AMP

  8. Transporter-mediated biofuel secretion.

    Science.gov (United States)

    Doshi, Rupak; Nguyen, Tuan; Chang, Geoffrey

    2013-05-07

    Engineering microorganisms to produce biofuels is currently among the most promising strategies in renewable energy. However, harvesting these organisms for extracting biofuels is energy- and cost-intensive, limiting the commercial feasibility of large-scale production. Here, we demonstrate the use of a class of transport proteins of pharmacological interest to circumvent the need to harvest biomass during biofuel production. We show that membrane-embedded transporters, better known to efflux lipids and drugs, can be used to mediate the secretion of intracellularly synthesized model isoprenoid biofuel compounds to the extracellular milieu. Transporter-mediated biofuel secretion sustainably maintained an approximate three- to fivefold boost in biofuel production in our Escherichia coli test system. Because the transporters used in this study belong to the ubiquitous ATP-binding cassette protein family, we propose their use as "plug-and-play" biofuel-secreting systems in a variety of bacteria, cyanobacteria, diatoms, yeast, and algae used for biofuel production. This investigation showcases the potential of expressing desired membrane transport proteins in cell factories to achieve the export or import of substances of economic, environmental, or therapeutic importance.

  9. Denial of Service Prevention for 5G

    DEFF Research Database (Denmark)

    Li, Yao; Kaur, Bipjeet; Andersen, Birger

    2011-01-01

    5G wireless mobile communication is expected to include a large number of advanced technologies in order to further increase bandwidth, Quality of Service (QoS), improve usability and security, decrease delays and cost of service. Software Defined Radio (SDR) will be the platform for advanced...... terminals. Our focus is security and especially prevention of Denial of Service (DoS) attacks which we believe will become more common in commercial networks through increasing availability of easy programmable SDRs. We propose a secret version of Adaptive Frequency Hopping, as a possible 5G technology...

  10. Kinetics of alpha-amylase secretion in Aspergillus oryzae

    DEFF Research Database (Denmark)

    Henriksen, Anne Laurence Santerre; Carlsen, Morten; Bang de, H.

    1999-01-01

    -chase experiments were carried out to investigate the alpha-amylase secretion kinetics in A. oryzae. No unglycosylated alpha-amylase was detected neither intracellularly nor extracellularly demonstrating that glycosylation was not the rate controlling step in the secretory pathway. The pulse chase experiments...... indicated that there are two pools of intracellular alpha-amylase: a fast secreted and a slow secreted. The secretion of those two pools were described with a kinetic model, which was fitted to the pulse chase experiments. (C) 1999 John Wiley & Sons, Inc. Biotechnol Bioeng 65: 76-82, 1999....

  11. Language Officialization in Puerto Rico: Group-Making Discourses of Protectionism and Receptivity

    Science.gov (United States)

    Shenk, Elaine

    2011-01-01

    This article applies social constructionism and groupism theory to discourses on language officialization in Puerto Rico. It examines three argumentative texts presented prior to the passage of Law #4 in 1991 making Spanish the sole official language of the island. Grounded critical discourse theory maintains that language form and content are…

  12. Strategies to Maintain School District Financial Solvency: Illinois School Business Officials' Recommendations

    Science.gov (United States)

    Williams, Ann C.; Kersten, Thomas A.

    2013-01-01

    The purpose of this study was to identify financial management strategies that school business officials have found most successful in achieving school district financial stability. To accomplish, 208 Illinois school business officials in six counties: Cook, DuPage, Kane, Lake, McHenry, and Will counties, excluding Chicago School District 299,…

  13. Official statistics and Big Data

    Directory of Open Access Journals (Sweden)

    Peter Struijs

    2014-07-01

    Full Text Available The rise of Big Data changes the context in which organisations producing official statistics operate. Big Data provides opportunities, but in order to make optimal use of Big Data, a number of challenges have to be addressed. This stimulates increased collaboration between National Statistical Institutes, Big Data holders, businesses and universities. In time, this may lead to a shift in the role of statistical institutes in the provision of high-quality and impartial statistical information to society. In this paper, the changes in context, the opportunities, the challenges and the way to collaborate are addressed. The collaboration between the various stakeholders will involve each partner building on and contributing different strengths. For national statistical offices, traditional strengths include, on the one hand, the ability to collect data and combine data sources with statistical products and, on the other hand, their focus on quality, transparency and sound methodology. In the Big Data era of competing and multiplying data sources, they continue to have a unique knowledge of official statistical production methods. And their impartiality and respect for privacy as enshrined in law uniquely position them as a trusted third party. Based on this, they may advise on the quality and validity of information of various sources. By thus positioning themselves, they will be able to play their role as key information providers in a changing society.

  14. Bile Formation and Secretion

    Science.gov (United States)

    Boyer, James L.

    2014-01-01

    Bile is a unique and vital aqueous secretion of the liver that is formed by the hepatocyte and modified down stream by absorptive and secretory properties of the bile duct epithelium. Approximately 5% of bile consists of organic and inorganic solutes of considerable complexity. The bile-secretory unit consists of a canalicular network which is formed by the apical membrane of adjacent hepatocytes and sealed by tight junctions. The bile canaliculi (~1 μm in diameter) conduct the flow of bile countercurrent to the direction of portal blood flow and connect with the canal of Hering and bile ducts which progressively increase in diameter and complexity prior to the entry of bile into the gallbladder, common bile duct, and intestine. Canalicular bile secretion is determined by both bile salt-dependent and independent transport systems which are localized at the apical membrane of the hepatocyte and largely consist of a series of adenosine triphosphate-binding cassette transport proteins that function as export pumps for bile salts and other organic solutes. These transporters create osmotic gradients within the bile canalicular lumen that provide the driving force for movement of fluid into the lumen via aquaporins. Species vary with respect to the relative amounts of bile salt-dependent and independent canalicular flow and cholangiocyte secretion which is highly regulated by hormones, second messengers, and signal transduction pathways. Most determinants of bile secretion are now characterized at the molecular level in animal models and in man. Genetic mutations serve to illuminate many of their functions. PMID:23897680

  15. The Official Radio and Television Institute in Spain

    Science.gov (United States)

    Ruiz, Anibal Arias

    1976-01-01

    A description of the Official School of Radio and Television which is designed to train university graduates in the fields of journalism, the sciences of cinema, radio and television, and advertising. (JY)

  16. SWOC ANALYSIS OF GOODS AND SERVICES TAX (GST): IMPLEMENTATION IN INDIA

    OpenAIRE

    Raghavendra Holla

    2016-01-01

    Goods and Services Tax (GST) is a type of indirect tax and it is one of biggest reform in Indian tax structure. The Goods and Service Tax Bill or GST Bill, officially known as The Constitution (One Hundred and Twenty-Second Amendment) Bill, 2014. 16 years wait is almost finished when Rajya Sabha and Lokh Sabha passed ’The Goods and Service Tax Bill’ in the month of August, 2017. Good and Service tax is also known as ‘National Value Added Tax’. India is a developing country; the main source fo...

  17. Threshold quantum secret sharing based on single qubit

    Science.gov (United States)

    Lu, Changbin; Miao, Fuyou; Meng, Keju; Yu, Yue

    2018-03-01

    Based on unitary phase shift operation on single qubit in association with Shamir's ( t, n) secret sharing, a ( t, n) threshold quantum secret sharing scheme (or ( t, n)-QSS) is proposed to share both classical information and quantum states. The scheme uses decoy photons to prevent eavesdropping and employs the secret in Shamir's scheme as the private value to guarantee the correctness of secret reconstruction. Analyses show it is resistant to typical intercept-and-resend attack, entangle-and-measure attack and participant attacks such as entanglement swapping attack. Moreover, it is easier to realize in physic and more practical in applications when compared with related ones. By the method in our scheme, new ( t, n)-QSS schemes can be easily constructed using other classical ( t, n) secret sharing.

  18. Weegee’s City Secrets

    OpenAIRE

    TRACHTENBERG, Alan

    2011-01-01

    En tant que photographe indépendant de meurtres, d’accidents, d’incendies, mais aussi de moments de loisirs dans la ville — de scènes de violence et de plaisir — Weegee travaillait essentiellement la nuit et utilisait un flash puissant associé à son appareil-photo de presse. Ses « secrets pour réaliser des photographies avec un flash » consistent à donner des conseils pratiques et techniques pour débutants. Mais au cœur de la rhétorique de ses « secrets » se trouvent des réflexions subtiles e...

  19. Official portrait of Astronaut Anna L. Fisher

    Science.gov (United States)

    1985-01-01

    Official portrait of Astronaut Anna L. Fisher. Fisher is posing with her helmet on the table in front of her and the American flag appears over the opposite shoulder (34357); Posing with an empty table in front of her and the American flag behind her (34358).

  20. 32 CFR 635.2 - Safeguarding official information.

    Science.gov (United States)

    2010-07-01

    ... official information. (a) Military police records are unclassified except when they contain national security information as defined in AR 380-5. (b) When military police records containing personal... records transmitted outside DOD per AR 25-55. (c) Military police records may also be released to Federal...

  1. 22 CFR 41.21 - Foreign Officials-General.

    Science.gov (United States)

    2010-04-01

    ...) Definitions. In addition to pertinent INA definitions, the following definitions are applicable: (1... possessing a travel document or other evidence of intention to enter or transit the United States to transact official business for that government or international organization. (2) Attendants, as used in INA 101(a...

  2. Official portrait of astronaut Stephen S. Oswald

    Science.gov (United States)

    1992-01-01

    Official portrait of astronaut Stephen S. Oswald. Oswald, a member of Astronaut Class 11, wears launch and entry suit (LES) with launch and entry helmet (LEH) positioned at his side. In the background is the United States (U.S.) flag and a space shuttle orbiter model.

  3. Identification and characterization of a type III secretion-associated chaperone in the type III secretion system 1 of Vibrio parahaemolyticus.

    Science.gov (United States)

    Akeda, Yukihiro; Okayama, Kanna; Kimura, Tomomi; Dryselius, Rikard; Kodama, Toshio; Oishi, Kazunori; Iida, Tetsuya; Honda, Takeshi

    2009-07-01

    Vibrio parahaemolyticus causes human gastroenteritis. Genomic sequencing of this organism has revealed that it has two sets of type III secretion systems, T3SS1 and T3SS2, both of which are important for its pathogenicity. However, the mechanism of protein secretion via T3SSs is unknown. A characteristic of many effectors is that they require specific chaperones for efficient delivery via T3SSs; however, no chaperone has been experimentally identified in the T3SSs of V. parahaemolyticus. In this study, we identified candidate T3SS1-associated chaperones from genomic sequence data and examined their roles in effector secretion/translocation and binding to their cognate substrates. From these experiments, we concluded that there is a T3S-associated chaperone, VecA, for a cytotoxic T3SS1-dependent effector, VepA. Further analysis using pulldown and secretion assays characterized the chaperone-binding domain encompassing the first 30-100 amino acids and an amino terminal secretion signal encompassing the first 5-20 amino acids on VepA. These findings will provide a strategy to clarify how the T3SS1 of V. parahaemolyticus secretes its specific effectors.

  4. Impaired insulin secretion in the spontaneous diabetes rats.

    Science.gov (United States)

    Kimura, K; Toyota, T; Kakizaki, M; Kudo, M; Takebe, K; Goto, Y

    1982-08-01

    Dynamics of insulin and glucagon secretion were investigated by using a new model of spontaneous diabetes rats produced by the repetition of selective breeding in our laboratories. The perfusion experiments of the pancreas showed that the early phase of insulin secretion to continuous stimulation with glucose was specifically impaired, although the response of the early phase to arginine was preserved. The glucose-induced insulin secretion in the nineth generation (F8) which had a more remarkably impaired glucose tolerance was more reduced than in the sixth generation (F5). No significant difference of glucagon secretion in response to arginine or norepinephrine was noted between the diabetes rats and control ones. The present data indicate that the defective insulin secretion is a primary derangement in a diabetic state of the spontaneous diabetes rat. This defect in the early phase of glucose-induced insulin secretion suggests the specific impairment of the recognition of glucose by the pancreatic beta-cells. The spontaneous diabetes rats are very useful as a model of disease for investigating pathophysiology of non-insulin dependent diabetes mellitus.

  5. Bucarest, Strictement Secret

    Directory of Open Access Journals (Sweden)

    Ionela Mihai

    2010-07-01

    Full Text Available L’émission Bucarest, strictement secret représente un documentaire organisésous la forme d’une série télé, qui dépeint le Bucarest à partir de deux perspectives: de l’histoire, de la conte et du lieu. La valeur d’une cité réside dans l’existence d’une mystique, d’un romantisme abscons, à part et des caractères empruntés de drames de Shakespeare, mystérieux, serrés d’angoisse et des secrets qui assombrissent leur existence. Par conséquence, le rôle du metteur en scène est de dévoiler leur vraie identité et de remettre en place, autant que possible, la vérité.

  6. "The Secret Garden": A Literary Journey.

    Science.gov (United States)

    Jordan, Anne Devereaux

    1998-01-01

    Outlines the life of Frances Hodgson Burnett, author of "The Secret Garden." Argues that it not only tells an enthralling tale, but takes readers on a journey through the history of English literature. Discusses the gothic tradition and romanticism of "The Secret Garden." Lists classic elements in the book and offers five ideas…

  7. Dig It! The Secrets of Soil

    Science.gov (United States)

    It! The Secrets of Soil Come and Explore! Discover the amazing world of soils with images and information from the Dig It! The Secrets of Soil exhibit from the Smithsonian's National Museum of Natural and new web content will be added over the coming months including a new soil blog. New Interactives

  8. Big Data as a Source for Official Statistics

    Directory of Open Access Journals (Sweden)

    Daas Piet J.H.

    2015-06-01

    Full Text Available More and more data are being produced by an increasing number of electronic devices physically surrounding us and on the internet. The large amount of data and the high frequency at which they are produced have resulted in the introduction of the term ‘Big Data’. Because these data reflect many different aspects of our daily lives and because of their abundance and availability, Big Data sources are very interesting from an official statistics point of view. This article discusses the exploration of both opportunities and challenges for official statistics associated with the application of Big Data. Experiences gained with analyses of large amounts of Dutch traffic loop detection records and Dutch social media messages are described to illustrate the topics characteristic of the statistical analysis and use of Big Data.

  9. Intracellular mediators of potassium-induced aldosterone secretion

    International Nuclear Information System (INIS)

    Ganguly, A.; Chiou, S.; Davis, J.S.

    1990-01-01

    We have investigated the intracellular messengers of potassium in eliciting aldosterone secretion in calf adrenal glomerulosa cells since there were unresolved issues relating to the role of phosphoinositides, cAMP and protein kinases. We observed no evidence of hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP 2 ) in 3 H-inositol labeled alf adrenal cells or increase of cAMP in response to potassium. Addition of calcium channel blocker, nitrendipine after stimulating adrenal glomerulosa cells with potassium, markedly inhibited aldosterone secretion. A calmodulin inhibitor (W-7) produced greater reduction of aldosterone secretion than an inhibitor of protein kinase C (H-7). These results suggest that a rise in cytosolic free calcium concentration through voltage-dependent calcium channel and calmodulin are the critical determinants of aldosterone secretion stimulated by potassium

  10. Apparent inhibition of β-fructosidase secretion by tunicamycin may be explained by breakdown of the unglycosylated protein during secretion

    International Nuclear Information System (INIS)

    Faye, L.; Chrispeels, M.J.

    1989-01-01

    Suspension-cultured carrot (Daucus carota) cells synthesize and secrete β-fructosidase, a glycoprotein with asparagine-linked glycans. Treatment of the cells with tunicamycin completely inhibits the apparent secretion of β-fructosidase as measured by the accumulation of the 35 S-labelled protein in the cell wall or the culture medium. In the past, such a result has been interpreted as an inhibition of secretion by tunicamycin, but we suggest another explanation based on the following results. In the presence of tunicamycin, unglycosylated β-fructosidase is synthesized and is associated with an endoplasmic-reticulum-rich microsomal fraction. Pulse-chase experiments show that the unglycosylated β-fructosidase does not remain in the cells and appears to be secreted in the same way as glycosylated β-fructosidase; however, no radioactive, unglycosylated β-fructosidase accumulates extracellularly (cell wall or medium). Protoplasts obtained from carrot cells secrete β-fructosidase protein and activity, and treatment of the protoplasts with tunicamycin results in the synthesis of unglycosylated β-fructosidase. In the presence of tunicamycin, there is no accumulation of β-fructosidase activity or unglycosylated β-fructosidase polypeptide in the protoplast incubation medium. These results are consistent with the interpretation that the glycans of β-fructosidase are necessary for its stability, and that in these suspension-cultured cells, the unglycosylated enzyme is degraded during the last stage(s) of secretion, or immediately after its arrival in the wall

  11. A new potential secretion pathway for recombinant proteins in Bacillus subtilis.

    Science.gov (United States)

    Wang, Guangqiang; Xia, Yongjun; Gu, Zhennan; Zhang, Hao; Chen, Yong Q; Chen, Haiqin; Ai, Lianzhong; Chen, Wei

    2015-11-10

    Secretion of cytoplasmic expressed proteins into growth media has significant advantages. Due to the lack of an outer membrane, Bacillus subtilis is considered as a desirable 'cell factory' for the secretion of recombinant proteins. However, bottlenecks in the classical pathway for the secretion of recombinant proteins limit its use on a wide scale. In this study, we attempted to use four typical non-classically secreted proteins as signals to export three recombinant model proteins to the culture medium. All four non-classically secreted proteins can direct the export of the intrinsically disordered nucleoskeletal-like protein (Nsp). Two of them can guide the secretion of alkaline phosphatase (PhoA). One can lead the secretion of the thermostable β-galactosidase BgaB, which cannot be secreted with the aid of typical Sec-dependent signal peptides. Our results show that the non-classically secreted proteins lead the recombinant proteins to the culture medium, and thus non-classical protein secretion pathways can be exploited as a novel secretion pathway for recombinant proteins.

  12. A translocator-specific export signal establishes the translocator-effector secretion hierarchy that is important for type III secretion system function

    Science.gov (United States)

    Tomalka, Amanda G.; Stopford, Charles M.; Lee, Pei-Chung; Rietsch, Arne

    2012-01-01

    Summary Type III secretion systems are used by many Gram-negative pathogens to directly deliver effector proteins into the cytoplasm of host cells. To accomplish this, bacteria secrete translocator proteins that form a pore in the host-cell membrane through which the effector proteins are then introduced into the host cell. Evidence from multiple systems indicates that the pore-forming translocator proteins are exported before effectors, but how this secretion hierarchy is established is unclear. Here we used the P. aeruginosa translocator protein PopD as a model to identify its export signals. The amino-terminal secretion signal and chaperone, PcrH, are required for export under all conditions. Two novel signals in PopD, one proximal to the chaperone-binding site and one at the very C-terminus of the protein, are required for export of PopD before effector proteins. These novel export signals establish the translocator-effector secretion hierarchy, which in turn, is critical for the delivery of effectors into host cells. PMID:23121689

  13. 75 FR 78211 - Proposed Information Collection; Comment Request; Questionnaire for Building Permit Official

    Science.gov (United States)

    2010-12-15

    ... Budget (OMB) clearance of the Questionnaire for Building Permit Official (SOC-QBPO). The Census Bureau uses the Computer-Assisted Personal Interviewing (CAPI) electronic questionnaire SOC-QBPO to collect...; Questionnaire for Building Permit Official AGENCY: U.S. Census Bureau, Commerce. ACTION: Notice. SUMMARY: The...

  14. 78 FR 69814 - Proposed Information Collection; Comment Request; Questionnaire for Building Permit Official

    Science.gov (United States)

    2013-11-21

    ... Management and Budget (OMB) clearance of the Questionnaire for Building Permit Official (SOC-QBPO). The Census Bureau uses the Computer-Assisted Personal Interviewing (CAPI) electronic questionnaire SOC-QBPO...; Questionnaire for Building Permit Official AGENCY: U.S. Census Bureau. ACTION: Notice. SUMMARY: The Department...

  15. Expressed prostatic secretion biomarkers improve stratification of NCCN active surveillance candidates: performance of secretion capacity and TMPRSS2:ERG models.

    Science.gov (United States)

    Whelan, Christopher; Kawachi, Mark; Smith, David D; Linehan, Jennifer; Babilonia, Gail; Mejia, Rosa; Wilson, Timothy; Smith, Steven S

    2014-01-01

    Active surveillance is a viable patient option for prostate cancer provided that a clinical determination of low risk and presumably organ confined disease can be made. To standardize risk stratification schemes the NCCN (National Comprehensive Cancer Network®) provides guidelines for the active surveillance option. We determined the effectiveness of expressed prostatic secretion biomarkers for detecting occult risk factors in NCCN active surveillance candidates. Expressed prostatic secretion specimens were obtained before robot-assisted radical prostatectomy. Secretion capacity biomarkers, including total RNA and expressed prostatic secretion specimen volume, were measured by standard techniques. RNA expression biomarkers, including TXNRD1 mRNA, prostate specific antigen mRNA, TMPRSS2:ERG fusion mRNA and PCA3 mRNA, were measured by quantitative reverse-transcription polymerase chain reaction. Of the 528 patients from whom expressed prostatic secretions were collected 216 were eligible for active surveillance under NCCN guidelines. Variable selection on logistic regression identified 2 models, including one featuring types III and VI TMPRSS2:ERG variants, and one featuring 2 secretion capacity biomarkers. Of the 2 high performing models the secretion capacity model was most effective for detecting cases in this group that were up-staged or up-staged plus upgraded. It decreased the risk of up-staging in patients with a negative test almost eightfold and decreased the risk of up-staging plus upgrading about fivefold while doubling the prevalence of up-staging in the positive test group. Noninvasive expressed prostatic secretion testing may improve patient acceptance of active surveillance by dramatically reducing the presence of occult risk factors among those eligible for active surveillance under NCCN guidelines. Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  16. 50 CFR 216.95 - Official mark for “Dolphin-safe” tuna products.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Official mark for âDolphin-safeâ tuna... AND IMPORTING OF MARINE MAMMALS Dolphin Safe Tuna Labeling § 216.95 Official mark for “Dolphin-safe... Department of Commerce that may be used to label tuna products that meet the “dolphin-safe” standards set...

  17. Standpoints and protection of business secrets

    Directory of Open Access Journals (Sweden)

    Brane Bertoncelj

    2001-06-01

    Full Text Available The human impact on an information system where data bases, containing business secretes, are stored is one of the most unreliable and unforeseeable factors. For this reason, it must not be underestimated. The results of this study indicate a correlation between behavioural intention and protection of business secretes. There is a statistically significant correlation between behavioural intention and behavioural supervision. This means that an increased level of perceived supervision over one's own behaviour is related to behavioural intention. A great majority of participants would not divulge a business secret due to internal moral factors, i.e., they possess the appropriate capabilities to determine the advantages of social moral values over personal values.

  18. Quantum secret sharing protocol using modulated doubly entangled photons

    International Nuclear Information System (INIS)

    Chuan, Wang; Yong, Zhang

    2009-01-01

    In this paper, we propose a quantum secret sharing protocol utilizing polarization modulated doubly entangled photon pairs. The measurement devices are constructed. By modulating the polarizations of entangled photons, the boss could encode secret information on the initial state and share the photons with different members to realize the secret sharing process. This protocol shows the security against intercept-resend attack and dishonest member cheating. The generalized quantum secret sharing protocol is also discussed. (general)

  19. Secret Places.

    Science.gov (United States)

    Ridolfi, Kerry

    1997-01-01

    Argues that children are as deep as the ocean, with secret places inside of them waiting to be opened. Notes that it is powerful for students to learn they can make sense of the world through words, and describes inviting them into poetry as they read poetry, create poetry packets, and write and revise poems. (SR)

  20. Lipids in airway secretions

    International Nuclear Information System (INIS)

    Bhaskar, K.R.; DeFeudis O'Sullivan, D.; Opaskar-Hincman, H.; Reid, L.M.

    1987-01-01

    Lipids form a significant portion of airway mucus yet they have not received the same attention that epithelial glycoproteins have. We have analysed, by thin layer chromatography, lipids present in airway mucus under 'normal' and hypersecretory (pathological) conditions.The 'normals' included (1) bronchial lavage obtained from healthy human volunteers and from dogs and (2) secretions produced ''in vitro'' by human (bronchial) and canine (tracheal) explants. Hypersecretory mucus samples included (1) lavage from dogs made bronchitic by exposure to SO 2 , (2) bronchial aspirates from acute and chronic tracheostomy patients, (3) sputum from patients with cystic fibrosis and chronic bronchitis and (4) postmortem secretions from patients who died from sudden infant death syndrome (SIDS) or from status asthmaticus. Cholesterol was found to be the predominant lipid in 'normal' mucus with lesser amounts of phospholipids. No glycolipids were detected. In the hypersecretory mucus, in addition to neutral and phospholipids, glycolipids were present in appreciable amounts, often the predominant species, suggesting that these may be useful as markers of disease. Radioactive precursors 14 C acetate and 14 C palmitate were incorporated into lipids secreted ''in vitro'' by canine tracheal explants indicating that they are synthesised by the airway. (author)

  1. A thyrotropin‑secreting macroadenoma with positive growth ...

    African Journals Online (AJOL)

    A thyrotropin‑secreting macroadenoma with positive growth hormone and prolactin immunostaining: A case report and literature review. ... thyroid hormone receptor resistance syndrome. Key words: Inappropriate thyroid stimulating hormone, thyrotropin‑secreting pituitary adenoma, thyroid stimulating hormone adenoma ...

  2. Are Teachers Public Officials for Defamation Purposes?

    Science.gov (United States)

    Bjorklun, Eugene C.

    1993-01-01

    Analyzes the law of defamation as it applies to teachers with special attention to the public official status of teachers. Concludes that public school teachers who are accused of deficiencies in the performance of their duties appear to have very little protection from false accusations under the law of defamation. (MLF)

  3. How Justice System Officials View Wrongful Convictions

    Science.gov (United States)

    Smith, Brad; Zalman, Marvin; Kiger, Angie

    2011-01-01

    The wrongful conviction of factually innocent people is a growing concern within the United States. Reforms generated by this concern are predicated in part on the views of justice system participants. The authors surveyed judges, police officials, prosecutors, and defense lawyers in Michigan regarding their views of why wrongful convictions…

  4. Identification of genes encoding the type IX secretion system and secreted proteins in Flavobacterium columnare IA-S-4

    Science.gov (United States)

    Flavobacterium columnare, a member of the phylum Bacteroidetes, causes columnaris disease in wild and aquaculture-reared freshwater fish. The mechanisms responsible for columnaris disease are not known. Many members of the phylum Bacteroidetes use type IX secretion systems (T9SSs) to secrete enzymes...

  5. The experiences of parents who report youth bullying victimization to school officials.

    Science.gov (United States)

    Brown, James R; Aalsma, Matthew C; Ott, Mary A

    2013-02-01

    Current research offers a limited understanding of parental experiences when reporting bullying to school officials. This research examines the experiences of middle-school parents as they took steps to protect their bullied youth. The qualitative tradition of interpretive phenomenology was used to provide in-depth analysis of the phenomena. A criterion-based, purposeful sample of 11 parents was interviewed face-to-face with subsequent phone call follow-ups. Interviews were taped, transcribed, and coded. MAX qda software was used for data coding. In analyzing the interviews, paradigm cases, themes, and patterns were identified. Three parent stages were found: discovering, reporting, and living with the aftermath. In the discovery stage, parents reported using advice-giving in hopes of protecting their youth. As parents noticed negative psychosocial symptoms in their youth escalate, they shifted their focus to reporting the bullying to school officials. All but one parent experienced ongoing resistance from school officials in fully engaging the bullying problem. In the aftermath, 10 of the 11 parents were left with two choices: remove their youth from the school or let the victimization continue. One paradigm case illustrates how a school official met parental expectations of protection. This study highlights a parental sense of ambiguity of school officials' roles and procedures related to school reporting and intervention. The results of this study have implications in the development and use of school-wide bullying protocols and parental advocacy.

  6. Health services needs of older persons: emerging findings from Tarakan City, East Kalimantan

    Directory of Open Access Journals (Sweden)

    Rina K. Kusumaratna

    2011-12-01

    Full Text Available As older persons are steadily increasing in number and there are no specialized comprehensive healthcare services for older persons in Indonesia, including East Kalimantan, the aim of the present study was to determine the extent of the problems facing healthcare staff and officials in Tarakan City, East Kalimantan, in providing comprehensive healthcare services attuned to the needs of older persons.This study was a qualitative interview-based survey with focus group discussions, involving heads and healthcare officials of seven puskesmas in Tarakan City, East Kalimantan district, with the addition of a number of district health planning officials. The results revealed a difference between daily hospital referral rate of older persons by puskesmas staff and actual daily hospital admission rate for the referrals. None of the consulted healthcare staff had any speciality education in geriatrics or older persons health. The older persons most frequently presented to the hospital with hypertension, diabetes, and myocardial insufficiency. On the other hand, at the health centers the presenting conditions were hypertension, gastroenteritis, rheumatism, sleep disorders, and upper respiratory tract infections. Improved access to healthcare for older persons should be achieved by improving knowledge and skills of human resources, including communication skills, and of supporting healthcare service infrastructure at puskesmas, specifically oriented towards the needs of and designed for use by older persons, such as ramps for wheelchairs, and handrails in corridors. Local governments should strengthen the appropriate service delivery to older persons, and provide support for the maintenance, sustainability and strengthening of community-based care for older persons.

  7. Health service needs of older persons: emerging findings from Tarakan City, East Kalimantan

    Directory of Open Access Journals (Sweden)

    Rina K. Kusumaratna

    2016-02-01

    Full Text Available As older persons are steadily increasing in number and there are no specialized comprehensive healthcare services for older persons in Indonesia, including East Kalimantan, the aim of the present study was to determine the extent of the problems facing healthcare staff and officials in Tarakan City, East Kalimantan, in providing comprehensive healthcare services attuned to the needs of older persons.This study was a qualitative interview-based survey with focus group discussions, involving heads and healthcare officials of seven puskesmas in Tarakan City, East Kalimantan district, with the addition of a number of district health planning officials. The results revealed a difference between daily hospital referral rate of older persons by puskesmas staff and actual daily hospital admission rate for the referrals. None of the consulted healthcare staff had any speciality education in geriatrics or older persons health. The older persons most frequently presented to the hospital with hypertension, diabetes, and myocardial insufficiency. On the other hand, at the health centers the presenting conditions were hypertension, gastroenteritis, rheumatism, sleep disorders, and upper respiratory tract infections. Improved access to healthcare for older persons should be achieved by improving knowledge and skills of human resources, including communication skills, and of supporting healthcare service infrastructure at puskesmas, specifically oriented towards the needs of and designed for use by older persons, such as ramps for wheelchairs, and handrails in corridors. Local governments should strengthen the appropriate service delivery to older persons, and provide support for the maintenance, sustainability and strengthening of community-based care for older persons.

  8. 37 CFR 2.154 - Publication in Official Gazette.

    Science.gov (United States)

    2010-07-01

    ..., DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Publication of Marks Registered Under 1905 Act § 2.154 Publication in Official Gazette. A notice of the claim of benefits under the Act of 1946 and a...

  9. VIP secreting tumours in infancy

    International Nuclear Information System (INIS)

    Davies, R.P.; Slavotinek, J.P.; Dorney, S.F.A.

    1990-01-01

    Vasoactive intestinal polypeptide (VIP) secreting neural crest tumours are an uncommon but important treatable cause of intractable childhood diarrhoea. The radiological appearances of two cases are presented with a review of radiological findings in childhood VIP secreting neural crest tumours. Twenty eight cases of childhood VIP secreting neural crest tumours were reviewed. Nineteen (68%) were ganglioneuroblastomas and nine (32%) were ganglioneuromas. The majority of tumours (66%) were in a paravertebral location in the abdomen indicating that a search for such a tumour should be initiated at this site. Eighteen of the twenty eight cases reviewed discussed relevant radiological investigations. Calcification was detected in 50% of abdominal radiographs. Gut dilatation was often a prominent feature. A mass was detected in 5 of 5 cases where ultrasound findings were reported, and seven of seven cases with CT findings reported. Prior to the availability of CT and ultrasound the most useful investigation was IVU which demonstrated evidence of a mass in 5 of 9 cases. The presence of paravertebral calcification and gut dilatation on the plain radiograph of a child with intractable diarrhoea suggests the presence of a VIP secreting neural crest tumour. If an abdominal tumour is not found in the appropriate clinical setting and VIP levels are elevated, a widespread search of the paravertebral region is indicated. (orig.)

  10. Autophagy-dependent secretion: contribution to tumor progression

    Directory of Open Access Journals (Sweden)

    Tom Keulers

    2016-11-01

    Full Text Available Autophagy is best known as a lysosomal degradation and recycling pathway to maintain cellular homeostasis. During autophagy, cytoplasmic content is recognized and packed in autophagic vacuoles, or autophagosomes, and targeted for degradation. However, during the last years, it has become evident that the role of autophagy is not restricted to degradation alone but also mediates unconventional forms of secretion. Furthermore, cells with defects in autophagy apparently are able to reroute their cargo, like mitochondria, to the extracellular environment; effects that contribute to an array of pathologies. In this review we discuss the current knowledge of the physiological roles of autophagy-dependent secretion, i.e. the effect on inflammation and insulin/ hormone secretion. Finally, we focus on the effects of autophagy-dependent secretion on the tumour microenvironment and tumour progression. The autophagy mediated secreted factors may stimulate cellular proliferation via auto- and paracrine signaling. The autophagy mediated release of immune modulating proteins change the immunosuppresive tumor microenvironment and may promote an invasive phenotype. These effects may be either direct or indirect through facilitating formation of the mobilized vesicle, aid in anterograde trafficking or alterations in homeostasis and/or autonomous cell signaling.

  11. Enhanced secretion of natto phytase by Bacillus subtilis.

    Science.gov (United States)

    Tsuji, Shogo; Tanaka, Kosei; Takenaka, Shinji; Yoshida, Ken-ichi

    2015-01-01

    Phytases comprise a group of phosphatases that trim inorganic phosphates from phytic acid (IP6). In this study, we aimed to achieve the efficient secretion of phytase by Bacillus subtilis. B. subtilis laboratory standard strain 168 and its derivatives exhibit no phytase activity, whereas a natto starter secretes phytase actively. The natto phytase gene was cloned into strain RIK1285, a protease-defective derivative of 168, to construct a random library of its N-terminal fusions with 173 different signal peptides (SPs) identified in the 168 genome. The library was screened to assess the efficiency of phytase secretion based on clear zones around colonies on plates, which appeared when IP6 was hydrolyzed. The pbp SP enhanced the secretion of the natto phytase most efficiently, i.e. twice that of the original SP. Thus, the secreted natto phytase was purified and found to remove up to 3 phosphates from IP6.

  12. Applying secret sharing for HIS backup exchange.

    Science.gov (United States)

    Kuroda, Tomohiro; Kimura, Eizen; Matsumura, Yasushi; Yamashita, Yoshinori; Hiramatsu, Haruhiko; Kume, Naoto; Sato, Atsushi

    2013-01-01

    To secure business continuity is indispensable for hospitals to fulfill its social responsibility under disasters. Although to back up the data of the hospital information system (HIS) at multiple remote sites is a key strategy of business continuity plan (BCP), the requirements to treat privacy sensitive data jack up the cost for the backup. The secret sharing is a method to split an original secret message up so that each individual piece is meaningless, but putting sufficient number of pieces together to reveal the original message. The secret sharing method eases us to exchange HIS backups between multiple hospitals. This paper evaluated the feasibility of the commercial secret sharing solution for HIS backup through several simulations. The result shows that the commercial solution is feasible to realize reasonable HIS backup exchange platform when template of contract between participating hospitals is ready.

  13. The Secret of Guided Missile Re-Entry,

    Science.gov (United States)

    1986-06-25

    I RD-PAI169 598 THE SECRET OF GUIDED MISSILE RE-ENTRY(U) FOREIGN / I TECHNOLOGY DIV NRIGHT-PATTERSON RFB OH J CHEN ET AL. I 25 JUN 96 FTD-ID(RS)T...TECHNOLOGY DIVISION THE SECRET OF GUIDED MISSILE RE-ENTRY by Chen Jingzhong, An Sehua J L 0 7 ’:;85’ ’ 0 *Approved for public release; Distribution...unlimite t d. :. 86 7 034.. FTD- ID(RS)T-0459-86 HUMAN TRANSLATION FTD-ID(RS)T-0459-86 25 June 1986 MICROFICHE NR: F - - 0Q 9? THE SECRET OF GUIDED

  14. Officiating Role Influences the Physical Match Activity Profiles of Rugby League Touch Judges and Referees

    Directory of Open Access Journals (Sweden)

    Pearce Leesa

    2017-08-01

    Full Text Available This study investigated the effect of the officiating role on physical activity profiles of rugby league match officials during match-play. Physical performance indicators were collated from 23 match officials, resulting in 78 observations. Match officials were categorised into two groups: referees and touch judges. Microtechnology facilitated the quantification of total distance (m, relative distance (m⋅min-1, maximum velocity (m⋅s-1, the percentage of high intensity running distance (% total > 3.01 m⋅s-1, walking distance (5 m⋅s-1. Multivariate analysis modelled the main effect of the officiating role with follow up univariate analyses identifying significant differences. A significant effect was noted (V = 750; F(8, 66 = 24.71; p < 0.05 with referees covering a greater total distance (7767 ± 585 vs. 7022 ± 759 m, relative distance (90 ± 6 vs. 82 ± 8 m⋅min-1, jogging distance (3772 ± 752 vs. 3110 ± 553 m, and fast jogging distance (2565 ± 631 vs. 1816 ± 440 m compared to touch judges. Touch judges covered greater distances while sprinting (1012 ± 385 vs. 654 ± 241 m. Results provide important guidance in the development of training programs for match officials.

  15. Impaired Follistatin Secretion in Cirrhosis

    DEFF Research Database (Denmark)

    Rinnov, Anders Rasmussen; Plomgaard, Peter; Pedersen, Bente Klarlund

    2016-01-01

    compared to healthy control participants. DESIGN, SETTING, AND PARTICIPANTS: To experimentally increase the glucagon-insulin ratio (mimicking the hormonal effect of exercise), we infused glucagon/somatostatin (to inhibit insulin secretion) and compared the acute follistatin increase in eight male cirrhosis...... controls (27.6 ± 3.8 vs 34.5 ± 2.9%, respectively; P = .001). CONCLUSIONS: Patients with cirrhosis show impaired capacity to acutely secrete follistatin. The decrease in acute follistatin release may contribute to the loss of muscle mass in liver cirrhosis....

  16. Official portrait of Astronaut Ronald E. McNair

    Science.gov (United States)

    1985-01-01

    Official portrait of Astronaut Ronald E. McNair. McNair is in the blue shuttle flight suit, standing in front of a table which holds a model of the Space Shuttle. An American flag is visible behind him.

  17. 10 CFR 1016.34 - Accountability for Secret Restricted Data.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Accountability for Secret Restricted Data. 1016.34 Section... Information § 1016.34 Accountability for Secret Restricted Data. Each permittee possessing documents containing Secret Restricted Data shall establish a document accountability procedure and shall maintain...

  18. Omeprazole promotes proximal duodenal mucosal bicarbonate secretion in humans

    DEFF Research Database (Denmark)

    Mertz-Nielsen, A; Hillingsø, Jens; Bukhave, K

    1996-01-01

    with control experiments. Also the combination of omeprazole and ranitidine increased (p = 0.05) duodenal bicarbonate secretion, while ranitidine alone caused no change in either basal or stimulated secretion. In the stomach basal as well as vagally stimulated bicarbonate secretion was independent of the means...

  19. A catalogue of human secreted proteins and its implications

    Directory of Open Access Journals (Sweden)

    Shivakumar Keerthikumar

    2016-11-01

    Full Text Available Under both normal and pathological conditions, cells secrete variety of proteins through classical and non-classical secretory pathways into the extracellular space. Majority of these proteins represent pathophysiology of the cell from which it is secreted. Recently, though more than 92% of the protein coding genes has been mapped by human proteome map project, but number of those proteins that constitutes secretome of the cell still remains elusive. Secreted proteins or the secretome can be accessible in bodily fluids and hence are considered as potential biomarkers to discriminate between healthy and diseased individuals. In order to facilitate the biomarker discovery and to further aid clinicians and scientists working in these arenas, we have compiled and catalogued secreted proteins from the human proteome using integrated bioinformatics approach. In this study, nearly 14% of the human proteome is likely to be secreted through classical and non-classical secretory pathways. Out of which, ~38% of these secreted proteins were found in extracellular vesicles including exosomes and shedding microvesicles. Among these secreted proteins, 94% were detected in human bodily fluids including blood, plasma, serum, saliva, semen, tear and urine. We anticipate that this high confidence list of secreted proteins could serve as a compendium of candidate biomarkers. In addition, the catalogue may provide functional insights in understanding the molecular mechanisms involved in various physiological and pathophysiological conditions of the cell.

  20. Affinity of antibody secreted by a single cell

    International Nuclear Information System (INIS)

    Doran, D.M.

    1978-01-01

    It was the intention of this research to measure the affinity of antibody secreted by a single cell, and to describe the spectrum of affinities displayed in response to antigenic stimulation. The single cell secreting specific antibody was isolated by means of the hemolytic plaque assay. The amount of antibody secreted by the cell was to be measured through the use of a solid phase radioimmunoassay. The affinity of the antibody would be estimated by comparing the diameter of the plaque, and the amount of antibody secreted, with a mathematical theory of the formation of a plaque in agar. As a test system, a solid phase radioimmunoassay was developed for human serum albumin using antibody coupled to Sephadex. A sensitivity of 1 nanogram was attained with this assay. A solid phase radioimmunoassay for mouse immunoglobulin M was developed, using antibody coupled to Sepharose. The sensitivity attained with this assay was only on the order of 10 micrograms. The mouse immunoglobulin M radioimmunoassay was not sensitive enough to measure the amount of antibody secreted by a single cell. From a theoretical equation, the relationship between antibody affinity, plaque diameter and antibody secretion rate was calculated for the experimental conditions used in this research. By assuming a constant antibody secretion rate, an effective binding constant for the antibody was estimated from the average plaque diameters. This effective binding constant was observed to increase during the immune response

  1. Helping Raise the Official Statistics Capability of Government Employees

    Directory of Open Access Journals (Sweden)

    Forbes Sharleen

    2016-12-01

    Full Text Available Both the production and the use of official statistics are important in the business of government. In New Zealand, concern persists about many government advisors’ low level of statistical capability. One programme designed specifically to enhance capability is New Zealand’s National Certificate of Official Statistics, first introduced in 2007 and originally targeted at government policy analysts and advisors. It now includes participants from many agencies, including the National Statistics Office. The competency-based 40-credit certificate comprises four taught units that aim to give students skills in basic official statistics and in critically evaluating statistical, research, policy, or media publications for their quality (of data, survey design, analysis, and conclusions and appropriateness for some policy issue (e.g., how to reduce problem gambling, together with an ‘umbrella’ workplace-based statistics project. Case studies are used to embed the statistics learning into the real-world context of these students. Several surveys of students and their managers were undertaken to evaluate the effectiveness of the certificate in terms of enhancing skill levels and meeting organisational needs and also to examine barriers to completion of the certificate. The results were used to both modify the programme and extend its international applicability.

  2. HLT profile of the official South African languages

    CSIR Research Space (South Africa)

    Grover, AS

    2010-05-01

    Full Text Available Human Language technologies (HLT) have been identified as a priority area by South African government to enable its eleven official languages technologically. We present the results of a technology audit for the South African HLT landscape...

  3. Enabling Bus Transit Service Quality Co-Monitoring Through Smartphone-Based Platform

    DEFF Research Database (Denmark)

    Li, Corinna; Zegras, P. Christopher; Zhao, Fang

    2017-01-01

    ’ word, meaning “agencies using public feedback to supplement official monitoring and regulation.”] bus service quality. The pilot project adapted a smartphone-based travel survey system, Future Mobility Sensing, to collect real-time customer feedback and objective operational measurements on specific...

  4. Controlul exercitat de serviciile secrete din România asupra politicii și presei – metatemă a alegerilor prezidențiale din 2014 (The Control of the Secret Services Over Politics and Media – Metatheme of the Presidential Election in 2014

    Directory of Open Access Journals (Sweden)

    Luminița KOHALMI

    2015-09-01

    Full Text Available The last Romanian presidential elections have been marked – more than in any other post-communist electoral races – by the public debate regarding the control of the secret services over politics and media. This research is focused on the presidential elections in 2014 and aims to analyze the subsequent items of this theme, its media impact, and its effect on the confidence that Romanians have in intelligence organizations, politics and media. This research is not aimed at discerning truth from fiction in the debates that have taken place with regards to the chosen theme. The results of the study validate the hypothesis that public interventions with regards to the theme have a medium and long term potential to shift the balance of power in Romania, by slicing antinomies on legal, institutional and ethical operation of intelligence into a democratic society.

  5. Humidification and secretion volume in mechanically ventilated patients.

    Science.gov (United States)

    Solomita, Mario; Palmer, Lucy B; Daroowalla, Feroza; Liu, Jeffrey; Miller, Dori; LeBlanc, Deniese S; Smaldone, Gerald C

    2009-10-01

    To determine potential effects of humidification on the volume of airway secretions in mechanically ventilated patients. Water vapor delivery from devices providing non-heated-wire humidification, heated-wire humidification, and heat and moisture exchanger (HME) were quantified on the bench. Then, patients requiring 24-hour mechanical ventilation were exposed sequentially to each of these humidification devices, and secretions were removed and measured by suctioning every hour during the last 4 hours of the 24-hour study period. In vitro water vapor delivery was greater using non-heated-wire humidification, compared to heated-wire humidification and HME. In vivo, a total of 9 patients were studied. Secretion volume following humidification by non-heated-wire humidification was significantly greater than for heated-wire humidification and HME (P=.004). The volume of secretions appeared to be linked to humidification, as greater water vapor delivery measured in vitro was associated with greater secretion volume in vivo.

  6. Secret key distillation from shielded two-qubit states

    International Nuclear Information System (INIS)

    Bae, Joonwoo

    2010-01-01

    The quantum states corresponding to a secret key are characterized using the so-called private states, where the key part consisting of a secret key is shielded by the additional systems. Based on the construction, it was shown that a secret key can be distilled from bound entangled states. In this work, I consider the shielded two-qubit states in a key-distillation scenario and derive the conditions under which a secret key can be distilled using the recurrence protocol or the two-way classical distillation, advantage distillation together with one-way postprocessing. From the security conditions, it is shown that a secret key can be distilled from bound entangled states in a much wider range. In addition, I consider the case that in which white noise is added to quantum states and show that the classical distillation protocol still works despite a certain amount of noise although the recurrence protocol does not.

  7. Type-IVC Secretion System: A Novel Subclass of Type IV Secretion System (T4SS) Common Existing in Gram-Positive Genus Streptococcus

    Science.gov (United States)

    Chen, Chen; Gao, George F.

    2012-01-01

    A growing number of pathogens are being found to possess specialized secretion systems which they use in various ways to subvert host defenses. Type IV secretion system (T4SS) is one of versatile secretion systems essential for the virulence and even survival of some bacteria species, and they enable the secretion of protein and DNA substrates across the cell envelope. T4SS was once believed to be present only in Gram-negative bacteria. In this study, we present evidence of a new subclass of T4SS, Type-IVC secretion system and indicate its common existence in the Gram-positive bacterial genus Streptococcus. We further identified that VirB1, VirB4, VirB6 and VirD4 are the minimal key components of this system. Using genome comparisons and evolutionary relationship analysis, we proposed that Type-IVC secretion system is movable via transposon factors and mediates the conjugative transfer of DNA, enhances bacterial pathogenicity, and could cause large-scale outbreaks of infections in humans. PMID:23056296

  8. Cell Secretion: Current Structural and Biochemical Insights

    Directory of Open Access Journals (Sweden)

    Saurabh Trikha

    2010-01-01

    Full Text Available Essential physiological functions in eukaryotic cells, such as release of hormones and digestive enzymes, neurotransmission, and intercellular signaling, are all achieved by cell secretion. In regulated (calcium-dependent secretion, membrane-bound secretory vesicles dock and transiently fuse with specialized, permanent, plasma membrane structures, called porosomes or fusion pores. Porosomes are supramolecular, cup-shaped lipoprotein structures at the cell plasma membrane that mediate and control the release of vesicle cargo to the outside of the cell. The sizes of porosomes range from 150nm in diameter in acinar cells of the exocrine pancreas to 12nm in neurons. In recent years, significant progress has been made in our understanding of the porosome and the cellular activities required for cell secretion, such as membrane fusion and swelling of secretory vesicles. The discovery of the porosome complex and the molecular mechanism of cell secretion are summarized in this article.

  9. The semantics of secrecy: young children's classification of secret content.

    Science.gov (United States)

    Anagnostaki, Lida; Wright, Michael J; Bourchier-Sutton, Alison J

    2010-01-01

    The authors explored whether young children can distinguish potential secrets from nonsecrets by their content, as can older children, adolescents, and adults. Ninety children, 4, 5, and 6 years old, rated the secrecy of items from an adult-validated list of personal information about an age- and gender-appropriate puppet. Two factors of the children's data corresponded to the adult categories of nonsecrets and secrets, and a third factor corresponded to surprises. All ages rated surprises as significantly more secret than nonsecret items; however, the surprise items contained linguistic cues to secrecy. A tendency to rate nonsecrets as secret decreased with age, but only the 6-year-olds rated secrets other than surprises as significantly more secret than nonsecrets. Thus, children acquire the implicit rules defining secret content from a somewhat later age than that reported for the cognitive or behavioral capacities for secrecy.

  10. 12 CFR 925.32 - Official membership insignia.

    Science.gov (United States)

    2010-01-01

    ... the words “Member Federal Home Loan Bank System.” [58 FR 43542, Aug. 17, 1993. Redesignated at 61 FR... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Official membership insignia. 925.32 Section 925.32 Banks and Banking FEDERAL HOUSING FINANCE BOARD FEDERAL HOME LOAN BANK MEMBERS AND HOUSING...

  11. Resource allocation in public health practice: a national survey of local public health officials.

    Science.gov (United States)

    Baum, Nancy M; DesRoches, Catherine; Campbell, Eric G; Goold, Susan Dorr

    2011-01-01

    The purpose of this study was to gain an empirical understanding of the types of allocation decisions local health officials (LHOs) make and the factors that influence those allocation decisions. We conducted a national survey of LHOs in the United States in 2008 to 2009. The sample was stratified by the size of the population served by the department. We merged our data with data from the 2008 National Association of County and City Health Officials Profile survey. Descriptive statistics were generated using weighted data. Our final sample size was 608 respondents, with an average of 10 years experience. The LHOs reported little shifting of resources among population groups but greater capacity to redirect staffing time. Less than half of LHOs reported using economic analyses or conducting needs assessments when setting priorities. Having sole provider status in a community strongly influenced LHOs' allocation decisions. In addition, the effectiveness of activities, previous budget allocations, and input from boards of health were influential factors in allocation decisions. Public expectations were moderately to very influential, but direct public input had a low impact on allocation decisions. Survey findings provide a clearer understanding of how LHOs fulfill their obligations as stewards of public health resources and ensure effective activities and access to needed services. It may be useful to assess the value of more structured allocation methods (eg, decision frameworks) in the allocation process. Expanding opportunities for public engagement in priority setting may also be valuable for difficult allocation decisions.

  12. The Future Internet: A World of Secret Shares

    Directory of Open Access Journals (Sweden)

    William J. Buchanan

    2015-11-01

    Full Text Available The Public Key Infrastructure (PKI is crumbling, partially due to the lack of a strong understanding of how encryption actually works, but also due to weaknesses in its implementation. This paper outlines an Internet storage technique using secret sharing methods which could be used to overcome the problems inherent with PKI, while supporting new types of architectures incorporating such things as automated failover and break-glass data recovery. The paper outlines a novel architecture: SECRET, which supports a robust cloud-based infrastructure with in-built privacy and failover. In order to understand the performance overhead of SECRET, the paper outlines a range of experiments that investigate the overhead of this and other secret share methods.

  13. An analysis on intersectional collaboration on non-communicable chronic disease prevention and control in China: a cross-sectional survey on main officials of community health service institutions.

    Science.gov (United States)

    Li, Xing-Ming; Rasooly, Alon; Peng, Bo; JianWang; Xiong, Shu-Yu

    2017-11-10

    Our study aimed to design a tool of evaluating intersectional collaboration on Non-communicable Chronic Disease (NCD) prevention and control, and further to understand the current status of intersectional collaboration in community health service institutions of China. We surveyed 444 main officials of community health service institutions in Beijing, Tianjin, Hubei and Ningxia regions of China in 2014 by using a questionnaire. A model of collaboration measurement, including four relational dimensions of governance, shared goals and vision, formalization and internalization, was used to compare the scores of evaluation scale in NCD management procedures across community healthcare institutions and other ones. Reliability and validity of the evaluation tool on inter-organizational collaboration on NCD prevention and control were verified. The test on tool evaluating inter-organizational collaboration in community NCD management revealed a good reliability and validity (Cronbach's Alpha = 0.89,split-half reliability = 0.84, the variance contribution rate of an extracted principal component = 49.70%). The results of inter-organizational collaboration of different departments and management segments showed there were statistically significant differences in formalization dimension for physical examination (p = 0.01).There was statistically significant difference in governance dimension, formalization dimension and total score of the collaboration scale for health record sector (p = 0.01,0.00,0.00). Statistical differences were found in the formalization dimension for exercise and nutrition health education segment (p = 0.01). There were no statistically significant difference in formalization dimension of medication guidance for psychological consultation, medical referral service and rehabilitation guidance (all p > 0.05). The multi-department collaboration mechanism of NCD prevention and control has been rudimentarily established. Community management

  14. Data analysis and review of radiology services at Glasgow 2014 Commonwealth Games

    International Nuclear Information System (INIS)

    Bethapudi, Sarath; Ritchie, David; Bongale, Santosh; Gordon, Jonny; MacLean, John; Mendl, Liz

    2015-01-01

    Medical services at the Glasgow 2014 Commonwealth Games (CWG) were provided though a purpose-built medical polyclinic, which had a fully equipped radiology department along with other services, set up within the main Games Village. Data analysis of radiology services offered at CWG has not been published before. Imaging services within the polyclinic, Athletes Village, Glasgow 2014 CWG. The aim of the paper is to analyse data on radiological investigations and assess the demand and distribution of workload on imaging services at CWG 2014. Data on radiology investigations at the CWG 2014 was retrieved from the Carestream picture archiving and communication system (PACS) and Pharmasys (CWG official centralised electronic database system) and analysed. Six hundred ninety-seven diagnostic and interventional procedures were performed. Of these 37.9 % were magnetic resonance imaging (MRI) scans, 22 % were diagnostic ultrasound (US) examinations, 33.1 % were radiographs, 4.3 % were computed tomography (CT) scans and 2.7 % were imaging-guided interventional procedures. 88 % of imaging was performed on athletes and the remainder were performed on team officials and workforce. Demand on radiology services gradually picked up through the pre-competition period and peaked half way through the CWG. Radiology played a vital role in the successful provision of medical services at the Glasgow 2014 CWG. High demand on imaging services can be expected at major international sporting events and therefore pre-event planning is vital. Having back-up facilities in case of technical failure should be given due importance when planning radiology services at future CWG events. (orig.)

  15. Data analysis and review of radiology services at Glasgow 2014 Commonwealth Games.

    Science.gov (United States)

    Bethapudi, Sarath; Ritchie, David; Bongale, Santosh; Gordon, Jonny; MacLean, John; Mendl, Liz

    2015-10-01

    Medical services at the Glasgow 2014 Commonwealth Games (CWG) were provided though a purpose-built medical polyclinic, which had a fully equipped radiology department along with other services, set up within the main Games Village. Data analysis of radiology services offered at CWG has not been published before. Imaging services within the polyclinic, Athletes Village, Glasgow 2014 CWG. The aim of the paper is to analyse data on radiological investigations and assess the demand and distribution of workload on imaging services at CWG 2014. Data on radiology investigations at the CWG 2014 was retrieved from the Carestream picture archiving and communication system (PACS) and Pharmasys (CWG official centralised electronic database system) and analysed. Six hundred ninety-seven diagnostic and interventional procedures were performed. Of these 37.9% were magnetic resonance imaging (MRI) scans, 22% were diagnostic ultrasound (US) examinations, 33.1% were radiographs, 4.3% were computed tomography (CT) scans and 2.7% were imaging-guided interventional procedures. 88% of imaging was performed on athletes and the remainder were performed on team officials and workforce. Demand on radiology services gradually picked up through the pre-competition period and peaked half way through the CWG. Radiology played a vital role in the successful provision of medical services at the Glasgow 2014 CWG. High demand on imaging services can be expected at major international sporting events and therefore pre-event planning is vital. Having back-up facilities in case of technical failure should be given due importance when planning radiology services at future CWG events.

  16. Data analysis and review of radiology services at Glasgow 2014 Commonwealth Games

    Energy Technology Data Exchange (ETDEWEB)

    Bethapudi, Sarath [County Durham Darlington Foundation NHS Trust, Durham (United Kingdom); Glasgow 2014 Commonwealth Games, Glasgow (United Kingdom); Ritchie, David [Glasgow 2014 Commonwealth Games, Glasgow (United Kingdom); Greater Glasgow and Clyde Hospitals NHS Trust, Western Infirmary, Glasgow (United Kingdom); Bongale, Santosh [Glasgow 2014 Commonwealth Games, Immediate Care Department, Glasgow (United Kingdom); NHS Greater Glasgow and Clyde, Royal Alexandra Hospital, Paisley (United Kingdom); Gordon, Jonny [Glasgow 2014 Commonwealth Games, Glasgow (United Kingdom); NHS Greater Glasgow and Clyde, Glasgow (United Kingdom); MacLean, John [Glasgow 2014 Commonwealth Games, Glasgow (United Kingdom); National Stadium Sports Medicine Centre, Glasgow (United Kingdom); Mendl, Liz [Glasgow 2014 Commonwealth Games, Glasgow (United Kingdom)

    2015-10-15

    Medical services at the Glasgow 2014 Commonwealth Games (CWG) were provided though a purpose-built medical polyclinic, which had a fully equipped radiology department along with other services, set up within the main Games Village. Data analysis of radiology services offered at CWG has not been published before. Imaging services within the polyclinic, Athletes Village, Glasgow 2014 CWG. The aim of the paper is to analyse data on radiological investigations and assess the demand and distribution of workload on imaging services at CWG 2014. Data on radiology investigations at the CWG 2014 was retrieved from the Carestream picture archiving and communication system (PACS) and Pharmasys (CWG official centralised electronic database system) and analysed. Six hundred ninety-seven diagnostic and interventional procedures were performed. Of these 37.9 % were magnetic resonance imaging (MRI) scans, 22 % were diagnostic ultrasound (US) examinations, 33.1 % were radiographs, 4.3 % were computed tomography (CT) scans and 2.7 % were imaging-guided interventional procedures. 88 % of imaging was performed on athletes and the remainder were performed on team officials and workforce. Demand on radiology services gradually picked up through the pre-competition period and peaked half way through the CWG. Radiology played a vital role in the successful provision of medical services at the Glasgow 2014 CWG. High demand on imaging services can be expected at major international sporting events and therefore pre-event planning is vital. Having back-up facilities in case of technical failure should be given due importance when planning radiology services at future CWG events. (orig.)

  17. Engineering signal peptides for enhanced protein secretion from Lactococcus lactis.

    Science.gov (United States)

    Ng, Daphne T W; Sarkar, Casim A

    2013-01-01

    Lactococcus lactis is an attractive vehicle for biotechnological production of proteins and clinical delivery of therapeutics. In many such applications using this host, it is desirable to maximize secretion of recombinant proteins into the extracellular space, which is typically achieved by using the native signal peptide from a major secreted lactococcal protein, Usp45. In order to further increase protein secretion from L. lactis, inherent limitations of the Usp45 signal peptide (Usp45sp) must be elucidated. Here, we performed extensive mutagenesis on Usp45sp to probe the effects of both the mRNA sequence (silent mutations) and the peptide sequence (amino acid substitutions) on secretion. We screened signal peptides based on their resulting secretion levels of Staphylococcus aureus nuclease and further evaluated them for secretion of Bacillus subtilis α-amylase. Silent mutations alone gave an increase of up to 16% in the secretion of α-amylase through a mechanism consistent with relaxed mRNA folding around the ribosome binding site and enhanced translation. Targeted amino acid mutagenesis in Usp45sp, combined with additional silent mutations from the best clone in the initial screen, yielded an increase of up to 51% in maximum secretion of α-amylase while maintaining secretion at lower induction levels. The best sequence from our screen preserves the tripartite structure of the native signal peptide but increases the positive charge of the n-region. Our study presents the first example of an engineered L. lactis signal peptide with a higher secretion yield than Usp45sp and, more generally, provides strategies for further enhancing protein secretion in bacterial hosts.

  18. The problem of using trade secrets in economic relations

    Directory of Open Access Journals (Sweden)

    А. О. Олефір

    2015-05-01

    Full Text Available Problem setting. In a market economy and increased competition between enterprises become increasingly important concepts such as business information, trade secrets, know-how, confidential information, the information with restricted access. Given the fact that only one patent protection is unable to meet the needs of researchers, in addition to formal public protection and secured legal means we would like to pay attention at private legal measures, particular, the mode of trade secrets. Recent research and publications analysis. Different aspects of the protection of trade secrets were investigated by specialists such as G. Androschuk, J. Berzhye, I. Davydov, O. Davydyuk, D. Zadyhaylo, P. Kraynov, G. Nikiforov, S. Nikiforov, V. Rubanov, E. Solovyov, L. Hoffman, V. Chaplygin, A. Cherniavsky and others. However, at present there is a lack of comprehensive research of this legal phenomenon, equally useful for innovators and businesses that actively protect corporate security. Paper objective. This article is planned to determine the legal characteristics, structural elements and mechanisms by which the use of trade secrets in business have a positive impact on innovation development and corporate security entities. Paper main body. On the basis of requirements of Art. 505 Civil Code of Ukraine and art. 39 of the TRIPS Agreement we formulated commercial information signs under which it receives legal protection as an object of intellectual property: (1 privacy (real or potential in the sense that it is as a whole or in a precise combination of aggregate and its components are not generally known or available to persons in the circles that normally deal with such information; (2 commercial value (not purely industrial or industrial, due to its secrecy; this information is unknown to others, which is a commercial interest; (3 the lawful holder of the information provides active special measures (technical, organizational, legal to preserve secrecy

  19. A Public Secret

    DEFF Research Database (Denmark)

    Bregnbæk, Susanne

    2011-01-01

    This article is based on anthropological fieldwork undertaken at two elite universities in Beijing. It addresses the paradoxical situation of the many instances of suicide among Chinese elite university students in Beijing, which constitute a public secret. The pressure of education weighs heavily...

  20. An unexpected knock on Corrigan’s secret door

    Science.gov (United States)

    Woywodt, Alexander

    2010-01-01

    Corrigan’s secret door describes a metaphorical escape route for busy physicians. The term was derived from the successful and exceptionally busy professional life of Irish physician Dominic John Corrigan (1802–80). It is claimed that Corrigan’s outpatient clinic was so busy that he required a secret door in his consulting rooms to escape from the ever-growing queue of eager patients. The origins of this charming story are unknown, and the door may have never existed. However, at present, Corrigan’s secret door is often quoted when busy physicians have their own little ways in surviving a stressful professional life. Generations of British-trained doctors have grown up with Corrigan’s secret door, as it was featured in the introduction of the Oxford Handbook of Clinical Medicine. Accordingly, trainees as well as more senior doctors are often reminded that having a ‘secret door’ is vital in surviving in the medical profession. My own escape is through classical music and the violoncello, in particular. As the name implies, my own secret door is normally invisible to colleagues and patients. This little article is about a patient who found me out, and a reflection on the role of classical music and the cello in my professional life. PMID:25984078

  1. Pathophysiology of glucagon secretion

    International Nuclear Information System (INIS)

    Boettger, J.; Pabst, H.W.

    1980-01-01

    Pathophysiology of glucagon secretion is reviewed in brief separating hyperglucagonemic from hypoclucagonemic states. Many questions concerning the role of glucagon in diabetes mellitus and in other diseases are still unresolved. The clucagon RIA is of clinical significance in a few diseases like glucagonoma, which may present without symptoms of the 'glucagonoma syndrome', the probably very rare hyperglucagonemia and some of the spontaneous hypoglycemias. Glucagon secretion may be evaluated by the determination of fasting immunoreactive glucagon (IRG) and by appropriate function tests as stimulation with i.v. arginine and suppression with oral glucose. However, the glucagon RIA at present is not a routine method, although commercial kits are available. Many pitfalls of radioimmunological glucagon determination still exist. (orig.) [de

  2. Biliary and pancreatic secretions in abdominal irradiation

    International Nuclear Information System (INIS)

    Becciolini, A.; Cionini, L.; Cappellini, M.; Atzeni, G.

    1979-01-01

    The biliary and pancreatic secretions have been determined in patients given pelvic or para-aortic irradiation, with a dose of 50 Gy in the former group and between 36 and 40 Gy in the latter. A test meal containing polyethylene glycol (PEG) as reference substance was used. Each sample of the duodenal content was assayed for volume, PEG content, amylase and trypsin activity, pH and biliary secretion. No significant modifications of biliary and pancreatic secretions were demonstrated after irradiation, suggesting that these functions are not involved in the pathogenesis of the malabsorption radiation syndrome. (Auth.)

  3. Pancreatic bicarbonate secretion involves two proton pumps.

    Science.gov (United States)

    Novak, Ivana; Wang, Jing; Henriksen, Katrine L; Haanes, Kristian A; Krabbe, Simon; Nitschke, Roland; Hede, Susanne E

    2011-01-07

    Pancreas secretes fluid rich in digestive enzymes and bicarbonate. The alkaline secretion is important in buffering of acid chyme entering duodenum and for activation of enzymes. This secretion is formed in pancreatic ducts, and studies to date show that plasma membranes of duct epithelium express H(+)/HCO(3)(-) transporters, which depend on gradients created by the Na(+)/K(+)-ATPase. However, the model cannot fully account for high-bicarbonate concentrations, and other active transporters, i.e. pumps, have not been explored. Here we show that pancreatic ducts express functional gastric and non-gastric H(+)-K(+)-ATPases. We measured intracellular pH and secretion in small ducts isolated from rat pancreas and showed their sensitivity to H(+)-K(+) pump inhibitors and ion substitutions. Gastric and non-gastric H(+)-K(+) pumps were demonstrated on RNA and protein levels, and pumps were localized to the plasma membranes of pancreatic ducts. Quantitative analysis of H(+)/HCO(3)(-) and fluid transport shows that the H(+)-K(+) pumps can contribute to pancreatic secretion in several species. Our results call for revision of the bicarbonate transport physiology in pancreas, and most likely other epithelia. Furthermore, because pancreatic ducts play a central role in several pancreatic diseases, it is of high relevance to understand the role of H(+)-K(+) pumps in pathophysiology.

  4. Novel Threshold Changeable Secret Sharing Schemes Based on Polynomial Interpolation.

    Science.gov (United States)

    Yuan, Lifeng; Li, Mingchu; Guo, Cheng; Choo, Kim-Kwang Raymond; Ren, Yizhi

    2016-01-01

    After any distribution of secret sharing shadows in a threshold changeable secret sharing scheme, the threshold may need to be adjusted to deal with changes in the security policy and adversary structure. For example, when employees leave the organization, it is not realistic to expect departing employees to ensure the security of their secret shadows. Therefore, in 2012, Zhang et al. proposed (t → t', n) and ({t1, t2,⋯, tN}, n) threshold changeable secret sharing schemes. However, their schemes suffer from a number of limitations such as strict limit on the threshold values, large storage space requirement for secret shadows, and significant computation for constructing and recovering polynomials. To address these limitations, we propose two improved dealer-free threshold changeable secret sharing schemes. In our schemes, we construct polynomials to update secret shadows, and use two-variable one-way function to resist collusion attacks and secure the information stored by the combiner. We then demonstrate our schemes can adjust the threshold safely.

  5. Catechin secretion and phytotoxicity

    Science.gov (United States)

    Kaushik, Shail

    2010-01-01

    Research indicates that the invasiveness of Centaurea stoebe is attributed to the stronger allelopathic effects on the native North American species than on the related European species, which is one of the unquestionable aspects of the “novel weapons hypothesis (NWH).” Studies originating from controlled to field conditions have shown that C. stoebe utilizes its biochemical potential to exert its invasiveness. The roots of C. stoebe secrete a potent phytotoxin, catechin, which has a detrimental effect on the surrounding plant species. Although, studies on catechin secretion and phytotoxicity represent one of the most well studied systems describing negative plant-plant interactions, it has also sparked controversies lately due to its phytotoxicity dosages and secretion effluxes. Previous reports negate the phytotoxic and pro-oxidant nature of catechin.1–3 In our recent study we have shown that catechin is highly phytotoxic against Arabidopsis thaliana and Festuca idahoensis. We also show that (±) catechin applied to roots of A. thaliana induces reactive oxygen species (ROS) confirming the pro-oxidant nature of catechin. In addition, activation of signature cell death genes such as acd2 and cad1 post catechin treatment in A. thaliana ascertains the phytotoxic nature of catechin. PMID:21057643

  6. ADMINISTRATIVE CIRCULAR NO. 20 USE OF PRIVATE VEHICLES FOR OFFICIAL DUTY - INSURANCE

    CERN Multimedia

    Human Resources Division - Tel. 73634

    2002-01-01

    Administrative Circular No. 20 on the use of private vehicles for official duty is shortly to be revised with a view to making certain procedures more flexible. CERN no longer requires members of the personnel to take out optional private insurances (insurance for official journeys, legal assistance insurance) in the case of duty travel for the Organization, since the associated risks are covered by CERN's own insurance. Pending the above mentioned revision, members of the personnel may continue to use their private vehicles for official duty in accordance with the others provisions laid down in the Circular Reminder: Owners of private vehicles must of course be insured by the normal compulsory car insurance required by the laws of the Host States when driving on and off the CERN sites.

  7. 14 CFR 1203.410 - Limitations.

    Science.gov (United States)

    2010-01-01

    ... original Top Secret classification authority. (g) The Administrator, the Chairperson, NASA Information Security Program Committee, or an official with original Top Secret classification authority may reclassify...

  8. Using public relations to market nursing service.

    Science.gov (United States)

    Camuñas, C

    1986-10-01

    Planned, skillful use of public relations in marketing nursing services can facilitate achievement of the nursing organization's goals and objectives. The local community, news media, bankers, local politicians, government officials, and social action groups all can take an active or reactive interest in nursing's activities. Public relations can provide an effective approach for achieving optimal results within the political and economic constraints of the current marketplace.

  9. Pathogenesis of canine cortisol-secreting adrenocortical tumors

    NARCIS (Netherlands)

    Kool, Miriam

    2015-01-01

    In dogs, hypercortisolism is one of the most frequently observed endocrine disorders, with an estimated incidence of about 1-2 cases per 1000 dogs per year. Approximately 15% of these cases is due to a cortisol-secreting adrenocortical tumor (AT). Cortisol-secreting ATs are characterized by

  10. Quantum secret sharing with classical Bobs

    International Nuclear Information System (INIS)

    Li Lvzhou; Qiu Daowen; Mateus, Paulo

    2013-01-01

    Boyer et al (2007 Phys. Rev. Lett. 99 140501) proposed a novel idea of semi-quantum key distribution, where a key can be securely distributed between Alice, who can perform any quantum operation, and Bob, who is classical. Extending the ‘semi-quantum’ idea to other tasks of quantum information processing is of interest and worth considering. In this paper, we consider the issue of semi-quantum secret sharing, where a quantum participant Alice can share a secret key with two classical participants, Bobs. After analyzing the existing protocol, we propose a new protocol of semi-quantum secret sharing. Our protocol is more realistic, since it utilizes product states instead of entangled states. We prove that any attempt of an adversary to obtain information necessarily induces some errors that the legitimate users could notice. (paper)

  11. Molecular Mechanisms of Insulin Secretion and Insulin Action.

    Science.gov (United States)

    Flatt, Peter R.; Bailey, Clifford J.

    1991-01-01

    Information and current ideas on the factors regulating insulin secretion, the mechanisms underlying the secretion and biological actions of insulin, and the main characteristics of diabetes mellitus are presented. (Author)

  12. Investment in secreted enzymes during nutrient-limited growth is utility dependent.

    Science.gov (United States)

    Cezairliyan, Brent; Ausubel, Frederick M

    2017-09-12

    Pathogenic bacteria secrete toxins and degradative enzymes that facilitate their growth by liberating nutrients from the environment. To understand bacterial growth under nutrient-limited conditions, we studied resource allocation between cellular and secreted components by the pathogenic bacterium Pseudomonas aeruginosa during growth on a protein substrate that requires extracellular digestion by secreted proteases. We identified a quantitative relationship between the rate of increase of cellular biomass under nutrient-limiting growth conditions and the rate of increase in investment in secreted proteases. Production of secreted proteases is stimulated by secreted signals that convey information about the utility of secreted proteins during nutrient-limited growth. Growth modeling using this relationship recapitulated the observed kinetics of bacterial growth on a protein substrate. The proposed regulatory strategy suggests a rationale for quorum-sensing-dependent stimulation of the production of secreted enzymes whereby investment in secreted enzymes occurs in proportion to the utility they confer. Our model provides a framework that can be applied toward understanding bacterial growth in many environments where growth rate is limited by the availability of nutrients.

  13. A secreted factor represses cell proliferation in Dictyostelium

    OpenAIRE

    Brock, Debra A.; Gomer, Richard H.

    2005-01-01

    Many cells appear to secrete factors called chalones that limit their proliferation, but in most cases the factors have not been identified. We found that growing Dictyostelium cells secrete a 60 kDa protein called AprA for autocrine proliferation repressor. AprA has similarity to putative bacterial proteins of unknown function. Compared with wild-type cells, aprA-null cells proliferate faster, while AprA overexpressing cells proliferate slower. Growing wild-type cells secrete a factor that i...

  14. Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.

    Science.gov (United States)

    Houtz, Jessica; Borden, Philip; Ceasrine, Alexis; Minichiello, Liliana; Kuruvilla, Rejji

    2016-11-07

    Insulin secretion by pancreatic islet β cells is critical for glucose homeostasis, and a blunted β cell secretory response is an early deficit in type 2 diabetes. Here, we uncover a regulatory mechanism by which glucose recruits vascular-derived neurotrophins to control insulin secretion. Nerve growth factor (NGF), a classical trophic factor for nerve cells, is expressed in pancreatic vasculature while its TrkA receptor is localized to islet β cells. High glucose rapidly enhances NGF secretion and increases TrkA phosphorylation in mouse and human islets. Tissue-specific deletion of NGF or TrkA, or acute disruption of TrkA signaling, impairs glucose tolerance and insulin secretion in mice. We show that internalized TrkA receptors promote insulin granule exocytosis via F-actin reorganization. Furthermore, NGF treatment augments glucose-induced insulin secretion in human islets. These findings reveal a non-neuronal role for neurotrophins and identify a new regulatory pathway in insulin secretion that can be targeted to ameliorate β cell dysfunction. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. The Use of Official Languages Act : Diversity Affirmed? | Pretorius ...

    African Journals Online (AJOL)

    Potchefstroom Electronic Law Journal/Potchefstroomse Elektroniese Regsblad ... The Act represents a very limited normative appreciation of this constitutional ... the use of official languages not being reserved for the legislative process, but ...

  16. 41 CFR 301-10.420 - When may I use a taxi, shuttle service or other courtesy transportation?

    Science.gov (United States)

    2010-07-01

    ..., shuttle service or other courtesy transportation? 301-10.420 Section 301-10.420 Public Contracts and... Courtesy Transportation § 301-10.420 When may I use a taxi, shuttle service or other courtesy... other courtesy transportation (if charges result), in the following manner: (1) At your official station...

  17. Cholinergic and VIPergic effects on thyroid hormone secretion in the mouse

    International Nuclear Information System (INIS)

    Ahren, B.

    1985-01-01

    The thyroid gland is known to harbor cholinergic and VIPergic nerves. In the present study, the influences of cholinergic stimulation by carbachol, cholinergic blockade by methylatropine and stimulation with various VIP sequences on basal, TSH-induced and VIP-induced thyroid hormone secretion were investigated in vivo in mice. The mice were pretreated with 125 I and thyroxine; the subsequent release of 125 I is an estimation of thyroid hormone secretion. It was found that basal radioiodine secretion was inhibited by both carbachol and methylatropine. Furthermore, TSH-induced radioiodine secretion was inhibited already by a low dose of carbachol. Moreover, a high dose of carbachol could inhibit VIP-induced radioiodine secretion. Methylatropine did not influence TSH- or VIP-stimulated radioiodine secretion, but counteracted the inhibitory action of carbachol on TSH- and VIP-induced radioiodine release. In addition, contrary to VIP, six various synthesized VIP fragments had no effect on basal or stimulated radioiodine release. It is concluded that basal thyroid hormone secretion is inhibited by both cholinergic activation and blockade. Furthermore, TSH-induced thyroid hormone secretion is more sensitive to inhibition with cholinergic stimulation than is VIP-induced thyroid hormone secretion. In addition, the VIP stimulation of thyroid hormone secretion seems to require the full VIP sequence

  18. Discovery of the type VII ESX-1 secretion needle?

    Science.gov (United States)

    Ates, Louis S; Brosch, Roland

    2017-01-01

    Mycobacterium tuberculosis, the etiological agent of human tuberculosis, harbours five ESAT-6/type VII secretion (ESX/T7S) systems. The first esx gene clusters were identified during the genome-sequencing project of M. tuberculosis H37Rv. Follow-up studies revealed additional genes playing important roles in ESX/T7S systems. Among the latter genes, one can find those that encode Pro-Glu (PE) and Pro-Pro-Glu (PPE) proteins as well as a gene cluster that is encoded >260 kb upstream of the esx-1 locus and encodes ESX-1 secretion-associated proteins EspA (Rv3616c), EspC (Rv3615c) and EspD (Rv3614c). The espACD cluster has been suggested to have an important function in ESX-1 secretion since EspA-EspC and EsxA-EsxB are mutually co-dependent on each other for secretion. However, the molecular mechanism of this co-dependence and interaction between the substrates remained unknown. In this issue of Molecular Microbiology, Lou and colleagues show that EspC forms high-molecular weight polymerization complexes that resemble selected components of type II, III and/or IV secretion systems of Gram-negative bacteria. Indeed, EspC-multimeric complexes form filamentous structures that could well represent a secretion needle of ESX-1 type VII secretion systems. This exciting observation opens new avenues for research to discover and characterize ESX/T7S components and elucidates the co-dependence of EsxA/B secretion with EspA/C. © 2016 John Wiley & Sons Ltd.

  19. Official website usage by university in crisis communication: Case study from Islamic University of Indonesia

    OpenAIRE

    Prastya, Narayana Mahendra

    2017-01-01

    This paper aims to discuss about crisis communication activities using official website in educational organizations. The case of this paper is how Islamic University of Indonesia (UII) responding the crisis following the death of three students in UII freshman orientation program. The data of this research using UII official statement that posted in the university official website between 23 January 2017- 31 January 2017. The consideration to choose the time frame because it was the most cri...

  20. [Chemical composition and chromaticity characteristic of Jilan glaze of Ming and Qing official kilns].

    Science.gov (United States)

    Wu, Jun-ming; Zhang, Mao-lin; Li, Qi-jiang; Wu, Juan; Quan, Kui-shan; Cao, Jian-wen

    2012-08-01

    Color glazes of Ming and Qing official kilns are excellent representatives of the famous ancient Chinese porcelains. The study of official ware with Jilan glaze has been an important topic. But it made slow progress due to the rarity of samples with strict production management and using system. The recipes, chemical composition and chromaticity characteristic of the Jilan samples excavated from official kilns in the Ming and Qing dynasties were first discussed by systematical testing with the energy dispersive X-ray fluorescence (EDXRF) and color difference meter. The results showed that the porcelain stone content in Jilan bodies of official kiln in the Ming dynasty is higher than the samples of the Qing dynasty. The manganese content in Jilan glazes of the Ming dynasty is higher than that in the Qing dynasty, while the glaze ash addition and the lightness value in the glaze are opposite.

  1. Behaviour of police officials towards mentally ill persons

    Directory of Open Access Journals (Sweden)

    Damir Juras

    2014-01-01

    Full Text Available The authors demonstrate the behaviour of police towards mentally ill individuals de lege lata and de lege ferenda. For this, they use an analysis of the existing Protection and Advocacy for the Mentally Ill Act, the draft of the new law which regulates that area, examples from practice, statistical data and the viewpoints of the legal and medical professions. This article points out the most frequent application of police powers when dealing with mentally ill persons and certain quandaries about the practice of admitting mentally ill persons into psychiatric institutions when they are a danger to themselves and others, that is, in the case of providing help to health workers dealing with mentally ill persons. Statistical data for the area of the Republic of Croatia point to a slight trend in the increase of police interventions over the last five years and also in the professional police approach towards such individuals. In conclusion, the coordinated activity of all services dealing with mentally ill persons is proposed as are additional education and the specialisation of police officials dealing with such persons. Furthermore, the need for balance between the necessity to protect the rights of mentally ill persons and the protection of rights and the security of the surroundings in which such persons live and the security of the entire community are pointed out.

  2. Proteomic Identification of Novel Secreted Antibacterial Toxins of the Serratia marcescens Type VI Secretion System*

    Science.gov (United States)

    Fritsch, Maximilian J.; Trunk, Katharina; Diniz, Juliana Alcoforado; Guo, Manman; Trost, Matthias; Coulthurst, Sarah J.

    2013-01-01

    It has recently become apparent that the Type VI secretion system (T6SS) is a complex macromolecular machine used by many bacterial species to inject effector proteins into eukaryotic or bacterial cells, with significant implications for virulence and interbacterial competition. “Antibacterial” T6SSs, such as the one elaborated by the opportunistic human pathogen, Serratia marcescens, confer on the secreting bacterium the ability to rapidly and efficiently kill rival bacteria. Identification of secreted substrates of the T6SS is critical to understanding its role and ability to kill other cells, but only a limited number of effectors have been reported so far. Here we report the successful use of label-free quantitative mass spectrometry to identify at least eleven substrates of the S. marcescens T6SS, including four novel effector proteins which are distinct from other T6SS-secreted proteins reported to date. These new effectors were confirmed as antibacterial toxins and self-protecting immunity proteins able to neutralize their cognate toxins were identified. The global secretomic study also unexpectedly revealed that protein phosphorylation-based post-translational regulation of the S. marcescens T6SS differs from that of the paradigm, H1-T6SS of Pseudomonas aeruginosa. Combined phosphoproteomic and genetic analyses demonstrated that conserved PpkA-dependent threonine phosphorylation of the T6SS structural component Fha is required for T6SS activation in S. marcescens and that the phosphatase PppA can reverse this modification. However, the signal and mechanism of PpkA activation is distinct from that observed previously and does not appear to require cell–cell contact. Hence this study has not only demonstrated that new and species-specific portfolios of antibacterial effectors are secreted by the T6SS, but also shown for the first time that PpkA-dependent post-translational regulation of the T6SS is tailored to fit the needs of different bacterial

  3. Secret rate - Privacy leakage in biometric systems

    NARCIS (Netherlands)

    Ignatenko, T.; Willems, F.M.J.

    2009-01-01

    Ahlswede and Csiszár [1993] introduced the concept of secret sharing. In their source model two terminals observe two correlated sequences. It is the objective of the terminals to form a common secret by interchanging a public message (helper data) in such a way that the secrecy leakage is

  4. 77 FR 9731 - Voluntary Service National Advisory Committee; Notice of Meeting

    Science.gov (United States)

    2012-02-17

    ... (requires prepayment). The March 15 business session will include remarks from local officials; the... activities, and ICARE customer service. On March 16, the morning business session will include subcommittee... female Volunteer of the Year awards. No time will be allocated at this meeting for receiving oral...

  5. Security of the AES with a Secret S-Box

    DEFF Research Database (Denmark)

    Tiessen, Tyge; Knudsen, Lars Ramkilde; Kölbl, Stefan

    2015-01-01

    How does the security of the AES change when the S-box is replaced by a secret S-box, about which the adversary has no knowledge? Would it be safe to reduce the number of encryption rounds? In this paper, we demonstrate attacks based on integral cryptanalysis which allow to recover both the secret...... key and the secret S-box for respectively four, five, and six rounds of the AES. Despite the significantly larger amount of secret information which an adversary needs to recover, the attacks are very efficient with time/data complexities of 217/216, 238/240 and 290/264, respectively. Another...

  6. Heterologous protein secretion in Lactococcus lactis: a novel antigen delivery system

    Directory of Open Access Journals (Sweden)

    Langella P.

    1999-01-01

    Full Text Available Lactic acid bacteria (LAB are Gram-positive bacteria and are generally regarded as safe (GRAS organisms. Therefore, LAB could be used for heterologous protein secretion and they are good potential candidates as antigen delivery vehicles. To develop such live vaccines, a better control of protein secretion is required. We developed an efficient secretion system in the model LAB, Lactococcus lactis. Staphylococcal nuclease (Nuc was used as the reporter protein. We first observed that the quantity of secreted Nuc correlated with the copy number of the cloning vector. The nuc gene was cloned on a high-copy number cloning vector and no perturbation of the metabolism of the secreting strain was observed. Replacement of nuc native promoter by a strong lactococcal one led to a significant increase of nuc expression. Secretion efficiency (SE of Nuc in L. lactis was low, i.e., only 60% of the synthesized Nuc was secreted. Insertion of a synthetic propeptide between the signal peptide and the mature moiety of Nuc increased the SE of Nuc. On the basis of these results, we developed a secretion system and we applied it to the construction of an L. lactis strain which secretes a bovine coronavirus (BCV epitope-protein fusion (BCV-Nuc. BCV-Nuc was recognized by both anti-BCV and anti-Nuc antibodies. Secretion of this antigenic fusion is the first step towards the development of a novel antigen delivery system based on LAB-secreting strains.

  7. Official Reports of Enrollment as of September 30, 2013. Montgomery County Public Schools

    Science.gov (United States)

    Erickson, Marianne

    2013-01-01

    This document is a combination of two reports produced for Montgomery County Public Schools (MCPS) by the Department of Policy, Records, and Reporting: (1) Official Race/Ethnic Membership of Students as of September 30, 2013; and (2) Official Report of Enrollment by Grade and School as of September 30, 2013. Both reports provide student data for…

  8. Human renin biosynthesis and secretion in normal and ischemic kidneys

    International Nuclear Information System (INIS)

    Pratt, R.E.; Carleton, J.E.; Richie, J.P.; Heusser, C.; Dzau, V.J.

    1987-01-01

    The pathway of renin biosynthesis and secretion in normal and ischemic human kidneys has been investigated by pulse-labeling experiments. The results indicate that in normal human kidney, preprorenin is rapidly processed to 47-kDa prorenin. Microradiosequencing showed that this molecule was generated by cleavage between Gly-23 and Leu-24, yielding a 43-amino acid proregion. Analysis of prorenin secreted by the kidney tissue yielded an identical sequence, indicating that prorenin is secreted without any further proteolysis. An examination of the kinetics of processing and secretion suggested that a majority of the newly synthesized prorenin is quickly secreted, while only a small fraction is processed intracellularly to the mature renin. The differences in secretion kinetics between prorenin and mature renin and the selective inhibition of prorenin secretion by monensin suggest that they are secreted independently via two pathways: a constitutive pathway probably from the Golgi or protogranules that rapidly release prorenin and a regulated pathway that secretes mature renin from the mature granules. A comparison of the kinetics of processing between normal and ischemic tissues suggests that renal ischemia leads to an overall increase in the rate of processing or prorenin to mature renin. In addition, prolonged biosynthetic labeling of renin in the ischemic kidney yielded two smaller molecular weight immunoreactive forms suggestive of renin fragments that may be degradative products. These fragments were not detected in normal kidney tissue labeled for similar lengths of time

  9. Constitutive protein secretion from the exocrine pancreas of fetal rats

    International Nuclear Information System (INIS)

    Arvan, P.; Chang, A.

    1987-01-01

    Two general kinds of exocytotic secretion of proteins are known: that which is stimulated by secretagogues; and constitutive exocytosis, which is unable to be stimulated. The exocrine pancreas has often been cited as a model system for the first kind of secretion. However, the release of digestive enzymes from the exocrine pancreas of 1-day prenatal rats cannot be stimulated by secretagogues; therefore, its secretion is constitutive. To gain insight into the intracellular pathways which mediate secretion in the fetal gland, we examined the kinetics of release of newly synthesized proteins. We find that fetal pancreas in a steady state of secretion releases pulse-labeled secretory proteins in two kinetically distinct phases. The first phase occurring during 0-6.5 h of chase comprises approximately 12% of total incorporated radioactivity, the second phase beginning at greater than 7 h of chase comprises the remainder. Based on analysis by electron microscope autoradiography, radiolabel is localized during the first phase of secretion in immature granules/condensing vacuoles, Golgi compartments, and few mature granules. The second phase of secretion occurs when radiolabel is predominantly in mature granules. We propose that secretion occurs via (at least) 2 exocytotic routes, both of which are constitutive in fetal pancreatic tissue

  10. 9 CFR 80.4 - Segregation of animals positive to an official Johne's disease test during interstate movement.

    Science.gov (United States)

    2010-01-01

    ... official Johne's disease test during interstate movement. 80.4 Section 80.4 Animals and Animal Products... animals positive to an official Johne's disease test during interstate movement. Animals that are positive... from the animals positive to an official Johne's disease test to the healthy animals in the vehicle. ...

  11. Multiparty Quantum Secret Sharing of Quantum States Using Entanglement States

    International Nuclear Information System (INIS)

    Ying, Guo; Da-Zu, Huang; Gui-Hua, Zeng; Ho, Lee Moon

    2008-01-01

    A multi-partite-controlled quantum secret sharing scheme using several non-orthogonal entanglement states is presented with unconditional security. In this scheme, the participants share the secret quantum state by exchanging the secret polarization angles of the disordered travel particles. The security of the secret quantum state is also guaranteed by the non-orthogonal multi-partite-controlled entanglement states, the participants' secret polarizations, and the disorder of the travelling particles. Moreover, the present scheme is secure against the particle-number splitting attack and the intercept-and-resend attack. It may be still secure even if the distributed quantum state is embedded in a not-so-weak coherent-state pulse

  12. 20 CFR 702.211 - Notice of employee's injury or death; designation of responsible official.

    Science.gov (United States)

    2010-04-01

    ... facilitate the filing of notices, each employer shall designate at least one individual responsible for...; designation of responsible official. 702.211 Section 702.211 Employees' Benefits EMPLOYMENT STANDARDS... of responsible official. (a) In order to claim compensation under the Act, an employee or claimant...

  13. 7 CFR 70.110 - Requirements for sanitation, facilities, and operating procedures in official plants.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Requirements for sanitation, facilities, and operating... Requirements for sanitation, facilities, and operating procedures in official plants. (a) The requirements for sanitation, facilities, and operating procedures in official plants shall be the applicable provisions stated...

  14. 31 CFR 515.553 - Bank accounts of official representatives in Cuba of foreign governments.

    Science.gov (United States)

    2010-07-01

    ... representatives in Cuba of foreign governments. 515.553 Section 515.553 Money and Finance: Treasury Regulations... Bank accounts of official representatives in Cuba of foreign governments. Specific licenses are issued authorizing payments from accounts of official representatives in Cuba of foreign governments for transactions...

  15. Adaptive Secret Sharing for Color Images

    Directory of Open Access Journals (Sweden)

    Jia-Hong Li

    2011-10-01

    Full Text Available A secret sharing model can secure a secret over multiple noise-like shadows and remain recoverable despite multiple shadow failures. Even if some of the shadows are compromised, the secret will not be revealed as long as the number of the compromised shadows is smaller than a pre-determined threshold. Moreover, there are some necessary details of concerns: the malicious tampering on shadows must be detectable; the shadows must be concealed in a camouflage image with adequate quality to reduce suspicion and possible attack; color image properties must be considered. In addition to these concerns, in this paper, an adaptable mechanism is further designed to balance the hiding quantity and the quality of camouflage images depending on different applications.This is an important and interesting aspect that has never been discussed in previous research.

  16. Requirements of the official permission of irradiation techniques

    International Nuclear Information System (INIS)

    Urban, A.

    1979-01-01

    The procedure and organization of the official licensing of radiation sources in Hungary are reviewed. Since January 1979 the radiation sources are qualified according to a uniform system of requirements for the Comecon countries. An example of qualification and the criteria of classification are detailed. (L.E.)

  17. 29 CFR 501.7 - Cooperation with Federal officials.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Cooperation with Federal officials. 501.7 Section 501.7 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF...

  18. Developing and Maintaining Official Government Agencies Web site - Issues and Challenges

    International Nuclear Information System (INIS)

    Mohd Fauzi Haris; Mohd Hasnor Hasan; Nuruliza Samsudin

    2011-01-01

    In the era where Internet technology has grown rapidly, information is now at your fingertips. Web site is considered as an important medium and widely used whether for the purposes of promoting products and services or as an effective way to disseminate general information about the organization, companies or individuals. Nowadays, a general term such as Web 2.0 is almost out of date and is now entering the era of the Real World Web. For government agencies for instance, official web site is an important and effective tool for dissemination and communication of information to the public. In the view of Web master for a government agency, a number of issues and challenges may arise. They might face the same issues and challenges but they way to handle them are differ from one agency to another, depending on the culture, special rules and regulations applied and shared values among the staff. This paper will discuss these issues and challenges as well as applicable solutions based on our experiences. (author)

  19. LcrQ and SycH function together at the Ysc type III secretion system in Yersinia pestis to impose a hierarchy of secretion.

    Science.gov (United States)

    Wulff-Strobel, Christine R; Williams, Andrew W; Straley, Susan C

    2002-01-01

    LcrQ is a regulatory protein unique to Yersinia. Previous study in Yersinia pseudotuberculosis and Yersinia enterocolitica prompted the model in which LcrQ negatively regulates the expression of a set of virulence proteins called Yops, and its secretion upon activation of the Yop secretion (Ysc) type III secretion system permits full induction of Yops expression. In this study, we tested the hypothesis that LcrQ's effects on Yops expression might be indirect. Excess LcrQ was found to exert an inhibitory effect specifically at the level of Yops secretion, independent of production, and a normal inner Ysc gate protein LcrG was required for this activity. However, overexpression of LcrQ did not prevent YopH secretion, suggesting that LcrQ's effects at the Ysc discriminate among the Yops. We tested this idea by determining the effects of deletion or overexpression of LcrQ, YopH and their common chaperone SycH on early Yop secretion through the Ysc. Together, our findings indicated that LcrQ is not a negative regulator directly, but it acts in partnership with SycH at the Ysc gate to control the entry of a set of Ysc secretion substrates. A hierarchy of YopH secretion before YopE appears to be imposed by SycH in conjunction with both LcrQ and YopH. LcrQ and SycH in addition influenced the deployment of LcrV, a component of the Yops delivery mechanism. Accordingly, LcrQ appears to be a central player in determining the substrate specificity of the Ysc.

  20. The View of Religious Officials on Organ Donation and Transplantation in the Zeytinburnu District of Istanbul.

    Science.gov (United States)

    Tarhan, Merve; Dalar, Levent; Yildirimoglu, Huseyin; Sayar, Adnan; Altin, Sedat

    2015-12-01

    One of the obstacles to organ donation and transplantation in Turkey is that of religious beliefs and, at this point, religious officials constitute a key aspect of this problem. Positive or negative viewpoints held by religious officials regarding organ donation and transplantation are influential in guiding the public. This descriptive study was conducted for the purpose of describing religious officials' viewpoints on this subject. To determine the opinions of 40 religious officials from among the imams and muezzins working in Zeytinburnu District Mufti (Religious Officials Superior) Station who participated in a normal meeting in April and who fully completed the survey. A 27-question survey form was used that consisted of open-ended and closed questions, 5 of which were on socio-demographic characteristics, 13 on viewpoints on organ donation and transplantation, and 9 on the Islamic viewpoint regarding organ donation and transplantation. For the analysis of the results, Student's t test and one-way ANOVA tests were used. It was found that all of the religious officials believed in the importance of organ donation, 80 % considered donating their organs, and 5 % had made an organ donation. Of the religious officials who had not donated organs, 35 % gave an answer that there was no specific reason and 27.5 % stated that they had never considered the subject. While the number of those stating that they would donate the organs of a close associate who had died, 77.5 % of them who did not want to donate gave as their reason the idea that if it were him, he would perhaps not want to give his organs after death. Of the religious officials questioned, 92.5 % asserted that the religion of Islam looked positively on organ donation and transplantation, 55 % stated that the knowledge of religious officials in the country was inadequate regarding this subject, and 65 % said that for interest in organ donation to increase, religious officials should make speeches and raise

  1. EDXRF analysis of Yanhedian Ru kiln and Jun official kiln porcelain

    International Nuclear Information System (INIS)

    Wen Chang; Zhao Huixian; Li Guoxia; Gao Zhengyao; Zhao Weijuan; Sun Hongwei; Guo Min; Xie Jianzhong; Li Rongwu; Guo Peiyu

    2009-01-01

    The chemical components of the body and glaze samples of some Ru porcelains from Yanhedian kiln and Jun official porcelains from Juntai kiln are determined by the technology of Energy Dispersive X-ray Fluorescence(EDXRF) in this work. The difference of the two kiln's glaze and body are analyzed by factor analysis method of Multi-dimensional statistical analysis. The results indicate that Yanhedian Ru porcelains can be well distinguished from Jun official porcelains from Juntai kiln. This evidence once again proves that Jun ceramics and Ru ceramics can be distinguished obviously. (authors)

  2. MONA Implementation Secrets

    DEFF Research Database (Denmark)

    Klarlund, Nils; Møller, Anders; Schwartzbach, Michael Ignatieff

    2002-01-01

    a period of six years. Compared to the first naive version, the present tool is faster by several orders of magnitude. This speedup is obtained from many different contributions working on all levels of the compilation and execution of formulas. We present a selection of implementation "secrets" that have...

  3. Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

    Directory of Open Access Journals (Sweden)

    Leonardo Iula

    2018-02-01

    Full Text Available Interleukin-1β (IL-1β, a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established. Neutrophils are essential players against bacterial and fungi infections. These cells are rapidly and massively recruited from the circulation into infected tissues and, beyond of displaying an impressive arsenal of toxic weapons effective to kill pathogens, are also an important source of IL-1β in infectious conditions. Here, we analyzed if an unconventional secretory autophagy mechanism is involved in the exportation of IL-1β by these cells. Our findings indicated that inhibition of autophagy with 3-methyladenine and Wortmannin markedly reduced IL-1β secretion induced by LPS + ATP, as did the disruption of the autophagic flux with Bafilomycin A1 and E64d. These compounds did not noticeable affect neutrophil viability ruling out that the effects on IL-1β secretion were due to cell death. Furthermore, VPS34IN-1, a specific autophagy inhibitor, was still able to reduce IL-1β secretion when added after it was synthesized. Moreover, siRNA-mediated knockdown of ATG5 markedly reduced IL-1β secretion in neutrophil-differentiated PLB985 cells. Upon LPS + ATP stimulation, IL-1β was incorporated to an autophagic compartment, as was revealed by its colocalization with LC3B by confocal microscopy. Overlapping of IL-1β-LC3B in a vesicular compartment peaked before IL-1β increased in culture supernatants. On the other hand, stimulation of autophagy by cell starvation augmented the colocalization of IL-1β and LC3B and then promoted neutrophil IL-1β secretion. In addition, specific ELISAs indicated that although both IL-1β and pro-IL-1β are released to culture supernatants upon neutrophil stimulation, autophagy only promotes IL-1β secretion. Furthermore, the serine proteases inhibitor

  4. 9 CFR 80.3 - Movement of domestic animals that are positive to an official Johne's disease test.

    Science.gov (United States)

    2010-01-01

    ... positive to an official Johne's disease test. 80.3 Section 80.3 Animals and Animal Products ANIMAL AND... animals that are positive to an official Johne's disease test. (a) Movement of domestic animals for slaughter. Domestic animals that are positive to an official Johne's disease test may be moved interstate...

  5. Uteroglobin, an apically secreted protein of the uterine epithelium, is secreted non-polarized form MDCK cells and mainly basolaterally from Caco-2 cells

    DEFF Research Database (Denmark)

    Vogel, L K; Suske, G; Beato, M

    1993-01-01

    A complete cDNA encoding rabbit uteroglobin was constructed and expressed in MDCK and Caco-2 cells. The MDCK cells secrete uteroglobin in approximately equal amounts to the apical and the basolateral side, whereas the Caco-2 cells secrete uteroglobin mainly to the basolateral side. Both MDCK...... and Caco-2 cells thus secrete uteroglobin in a non-sorted manner. It has, however, previously been shown that uteroglobin is secreted exclusively at the apical membrane in primary cell culture of endometrial epithelial cells [S.K. Mani et al. (1991) Endocrinology 128, 1563-1573]. This suggests that either...... the endometrial epithelium has an apical default pathway or recognises a sorting signal not recognised by MDCK cells and Caco-2 cells. Our data thus show that a soluble molecule can be secreted at the apical, the basolateral or both membranes depending on the cell type....

  6. Resources and estuarine health: Perceptions of elected officials and recreational fishers

    Energy Technology Data Exchange (ETDEWEB)

    Burger, J.; Sanchez, J.; McMahon, M.; Leonard, J.; Lord, C.G.; Ramos, R.; Gochfeld, M.

    1999-10-29

    It is important to understand the perceptions of user groups regarding both the health of their estuaries and environmental problems requiring management. Recreational fishers were interviewed to determine the perceptions of one of the traditional user groups of Barnegat Bay (New Jersey), and elected officials were interviewed to determine if the people charged with making decisions about environmental issues in the bay held similar perceptions. Although relative ratings were similar, there were significant differences in perceptions of the severity of environmental problems, and for the most part, public officials thought the problems were more severe than did the fishers. Personal watercraft (often called Jet Skis) were rated as the most severe problem, followed by chemical pollution, junk, over fishing, street runoff, and boat oil. Small boats, sailboats, wind surfers, and foraging birds were not considered environmental problems by either elected officials or fishermen. The disconnect between the perceptions of the recreational fishers and those of the locally elected public officials suggests that officials may be hearing from some of the more vocal people about problems, rather than from the typical fishers. Both groups felt there were decreases in some of the resources in the bay; over 50% felt the number of fish and crabs had declined, the size of fish and crabs had declined, and the number of turtles had declined. Among recreational fishers, there were almost no differences in perceptions of the severity of environmental problems or in changes in the bay. The problems that were rated the most severe were personal watercraft and over fishing by commercial fishers. Recreational fishers ranked sailboats, wind surfers, and fishing by birds as posing no problem for the bay. Most fishers felt there had been recent major changes in Barnegat Bay, with there now being fewer and smaller fish, fewer and smaller crabs, and fewer turtles. The results suggest that the

  7. An empirical typology of energy services based on a well-developed market: France

    International Nuclear Information System (INIS)

    Duplessis, Bruno; Adnot, Jérôme; Dupont, Maxime; Racapé, François

    2012-01-01

    The investigation is an attempt to apply a set of consistent and official definitions of energy services (ES), energy efficiency services (EES) and energy performance contracting (EPC) on a well-developed market: France. After defining the historical context of the French market the authors describe the types of offers that are presently made and that fall within the definition of energy services. There are many classic and novel factors for the success of energy services. For instance, the energy services market is now partly structured by the CEE scheme, the French ‘white certificates’ or ‘energy certificates scheme’. Also the grid problems lead to new services. The companies active on the market are described as a result of an empirical survey of ES market in France. This empirical survey of ES market in France includes estimates of the number of companies and of their turnover both for ES and EES. Examples and case studies are developed as a background. - Highlights: ► We apply a consistent and official set of definitions of energy services (ES). ► French ES market is structured by historical ES and shaped by recent evolutions. ► French ES market is now partly structured by white certificates and grid management. ► We describe the companies active on French market through an empirical survey. ► We have estimated French market size (actors and turnover) both for ES and EES.

  8. 25 CFR 2.19 - Action by Area Directors and Education Programs officials on appeal.

    Science.gov (United States)

    2010-04-01

    ... Programs officials on appeal. (a) Area Directors, Area Education Programs Administrators, Agency... 25 Indians 1 2010-04-01 2010-04-01 false Action by Area Directors and Education Programs officials on appeal. 2.19 Section 2.19 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR PROCEDURES...

  9. A History of “Who Speaks for Islam?” in Bosnia-Herzegovina: An Official Versus Popular Islam Debate

    Directory of Open Access Journals (Sweden)

    Hüsrev Tabak

    2017-06-01

    Full Text Available This paper examines the organisation of popular and official Islam during and after communism in Bosnia-Herzegovina. Through studying the interaction between the popular and the official forms of Islam in the historical context, this paper unfolds the debate on who speaks for Islam? That took place between official representatives and popular Islamic groups and movements in the former Yugoslavian republic. Such an enquiry revealed firstly that a close contact with the existing regime (regardless of its ideology is essential for becoming and remaining as the official Islamic authority, as seen in the Islamic Community’s pro-Titoist stance throughout in the former Yugoslavia. The findings of the enquiry secondly suggest that popular Islam and official Islam represent transitive positions; meaning that a popular Islamic movement can become the official Islam, vice versa. Accordingly, a former popular Islam front, the Mladi Muslimani (Young Muslims, in Yugoslavia evolved into an official Islamic authority after the dissolution of the country and by the Bosnia-Herzegovina’s establishment, in the scope of which new popular Islamic groups bred.

  10. Investigating the congruence of crowdsourced information with official government data: the case of pediatric clinics.

    Science.gov (United States)

    Kim, Minki; Jung, Yuchul; Jung, Dain; Hur, Cinyoung

    2014-02-03

    Health 2.0 is a benefit to society by helping patients acquire knowledge about health care by harnessing collective intelligence. However, any misleading information can directly affect patients' choices of hospitals and drugs, and potentially exacerbate their health condition. This study investigates the congruence between crowdsourced information and official government data in the health care domain and identifies the determinants of low congruence where it exists. In-line with infodemiology, we suggest measures to help the patients in the regions vulnerable to inaccurate health information. We text-mined multiple online health communities in South Korea to construct the data for crowdsourced information on public health services (173,748 messages). Kendall tau and Spearman rank order correlation coefficients were used to compute the differences in 2 ranking systems of health care quality: actual government evaluations of 779 hospitals and mining results of geospecific online health communities. Then we estimated the effect of sociodemographic characteristics on the level of congruence by using an ordinary least squares regression. The regression results indicated that the standard deviation of married women's education (P=.046), population density (P=.01), number of doctors per pediatric clinic (P=.048), and birthrate (P=.002) have a significant effect on the congruence of crowdsourced data (adjusted R²=.33). Specifically, (1) the higher the birthrate in a given region, (2) the larger the variance in educational attainment, (3) the higher the population density, and (4) the greater the number of doctors per clinic, the more likely that crowdsourced information from online communities is congruent with official government data. To investigate the cause of the spread of misleading health information in the online world, we adopted a unique approach by associating mining results on hospitals from geospecific online health communities with the sociodemographic

  11. Religious officials' knowledge, attitude, and behavior towards smoking and the new tobacco law in Kahramanmaras, Turkey.

    Science.gov (United States)

    Sucakli, Mustafa Haki; Ozer, Ali; Celik, Mustafa; Kahraman, Hasan; Ekerbicer, Hasan Cetin

    2011-07-28

    Tobacco control effort should be first started in people that are looked upon as role models for the general population. We aimed to determine the knowledge, attitude, and behavior of religious officials towards smoking and the new tobacco law. The study group was comprised of 492 Imams and 149 Quran course instructors working in Kahramanmaras city of Turkey, 641 religious officials in total, and our survey form was applied on 406 (63.3%) of those religious officials who agreed to participate in the study. Twenty-eight (6.9%) participants were current smokers and 35 (8.6%) were ex-smokers. 99.8% of the religious officials believed that smoking was harmful and/or prohibited in terms of religion. While 43.6% respondents thought smoking was "haram" (forbidden by Islam), 56.2% believed it was "makruh" (something regarded as reprehensible, though not forbidden by God according to Islam). 85.2% of the participants were aware of the recent tobacco law. 55.5% of the respondents, who were aware of the recent tobacco law, evaluated their knowledge level on the law as adequate, whereas 44.5% evaluated it as inadequate 92.4% of the participants noted that religious officials should play active roles in tobacco control effort. Smoking rate among religious officials is much lower than that of general public. In order to help religious officials to take a more active role on this issue, they should be trained on the subject and appropriate platforms should be established.

  12. 18 CFR 1316.10 - Officials not to benefit.

    Science.gov (United States)

    2010-04-01

    ... breach of this contract, and TVA shall have the right to exercise all remedies provided in this contract... GENERAL CONDITIONS AND CERTIFICATIONS FOR INCORPORATION IN CONTRACT DOCUMENTS OR ACTIONS Text of Conditions and Certifications § 1316.10 Officials not to benefit. When so indicated in TVA contract documents...

  13. 29 CFR 501.46 - Retention of official record.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Retention of official record. 501.46 Section 501.46 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF THE...

  14. 29 CFR 502.6 - Cooperation with DOL officials.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Cooperation with DOL officials. 502.6 Section 502.6 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF THE...

  15. 29 CFR 502.46 - Retention of official record.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Retention of official record. 502.46 Section 502.46 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS ENFORCEMENT OF CONTRACTUAL OBLIGATIONS FOR TEMPORARY ALIEN AGRICULTURAL WORKERS ADMITTED UNDER SECTION 218 OF THE...

  16. Excreted/Secreted Proteins from Trypanosome Procyclic Strains

    Directory of Open Access Journals (Sweden)

    Celestine Michelle Atyame Nten

    2010-01-01

    Full Text Available Trypanosoma secretome was shown to be involved in parasite virulence and is suspected of interfering in parasite life-cycle steps such as establishment in the Glossina midgut, metacyclogenesis. Therefore, we attempted to identify the proteins secreted by procyclic strains of T. brucei gambiense and T. brucei brucei, responsible for human and animal trypanosomiasis, respectively. Using mass spectrometry, 427 and 483 nonredundant proteins were characterized in T. brucei brucei and T. brucei gambiense secretomes, respectively; 35% and 42% of the corresponding secretome proteins were specifically secreted by T. brucei brucei and T. brucei gambiense, respectively, while 279 proteins were common to both subspecies. The proteins were assigned to 12 functional classes. Special attention was paid to the most abundant proteases (14 families because of their potential implication in the infection process and nutrient supply. The presence of proteins usually secreted via an exosome pathway suggests that this type of process is involved in trypanosome ESP secretion. The overall results provide leads for further research to develop novel tools for blocking trypanosome transmission.

  17. Omeprazole promotes proximal duodenal mucosal bicarbonate secretion in humans

    DEFF Research Database (Denmark)

    Mertz-Nielsen, Anette; Hillingsø, J; Bukhave, Klaus

    1996-01-01

    this incidental finding is explained by more potent gastric acid inhibition by omeprazole or might be caused by the different mode of drug action. Basal and stimulated gastric and duodenal bicarbonate secretion rates were measured in the same subjects in control experiments (n=17) and after pretreatment with high......H 6.9 v 6.8; p>0.05). Omeprazole caused higher rates of basal (mean (SEM)) (597 (48) v 351 (39) mu mol/h; pstimulated (834 (72) v 474 (66) mu mol/h; pstimulated (3351 (678) v 2550 (456) mu mol/h; p>0.05) duodenal bicarbonate secretion compared with control...... experiments. Also the combination of omeprazole and ranitidine increased (p=0.05) duodenal bicarbonate secretion, while ranitidine alone caused no change in either basal or stimulated secretion. In the stomach basal as well as vagally stimulated bicarbonate secretion was independent of the means of acid...

  18. Salivary Gland Secretion.

    Science.gov (United States)

    Dorman, H. L.; And Others

    1981-01-01

    Describes materials and procedures for an experiment utilizing a live dog to demonstrate: (1) physiology of the salivary gland; (2) parasympathetic control of the salivary gland; (3) influence of varying salivary flow rates on sodium and potassium ions, osmolarity and pH; and (4) salivary secretion as an active process. (DS)

  19. Challenges to the Reliability of Officially Published Statistics for ...

    African Journals Online (AJOL)

    Challenges to the Reliability of Officially Published Statistics for Extension Work. ... AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search · USING ... of Nigeria based on the National Bureau of Statistics, for the period 1972-2007.

  20. Computed tomographic study of hormone-secreting microadenomas

    International Nuclear Information System (INIS)

    Hemminghytt, S.; Kalkhoff, R.K.; Daniels, D.L.; Williams, A.L.; Grogan, J.P.; Haughton, V.M.

    1983-01-01

    A review was made of the computed tomographic (CT) studies of 33 patients with hormone-secreting microadenomas that had been verified by transsphenoidal surgery and endocrinologic evaluation. In previous studies in small series of patients, the CT appearance of pituitary microadenomas has been reported as hypodense, isodense, and hyperdense. In this study, CT showed a region of diminished enhancement and ususally an enlarged pituitary gland in cases of prolactin-secreting adenomas. HGH- or ACTH-secreting adenomas were less consistently hypodense. It is concluded that hypodensity and enlargement in the pituitary gland are the most useful criteria for identification of microadenomas. Some technical factors that may affect the CT appearance of microadenomas and lead to conflicting reports are discussed

  1. Exploring Quantum Supremacy in Access Structures of Secret Sharing by Coding Theory

    OpenAIRE

    Matsumoto, Ryutaroh

    2018-01-01

    We consider secret sharing schemes with a classical secret and quantum shares. One example of such schemes was recently reported whose access structure cannot be realized by any secret sharing schemes with classical shares. In this paper, we report further quantum secret sharing schemes whose access structures cannot be realized by any classical secret sharing schemes.

  2. Weegee’s City Secrets

    Directory of Open Access Journals (Sweden)

    Alan TRACHTENBERG

    2010-03-01

    Full Text Available En tant que photographe indépendant de meurtres, d’accidents, d’incendies, mais aussi de moments de loisirs dans la ville — de scènes de violence et de plaisir — Weegee travaillait essentiellement la nuit et utilisait un flash puissant associé à son appareil-photo de presse. Ses « secrets pour réaliser des photographies avec un flash » consistent à donner des conseils pratiques et techniques pour débutants. Mais au cœur de la rhétorique de ses « secrets » se trouvent des réflexions subtiles et convaincantes révélant la relation entre la lumière et l’obscurité, et plus particulièrement la manière dont la lumière du flash permet de rendre visible l’obscurité. Dans le récit de Weegee, le flash confère à la photographie le pouvoir d’écrire — d’écrire avec la lumière, un mode de représentation singulièrement approprié pour enregistrer des instants de vie dans les rues nocturnes de la ville.As a freelance photographer of crime, accidents, fires, and also of the recreational life of the city—scenes of violence and of pleasure—Weegee worked mainly at night and employed a powerful photoflash attachment to his press camera. His "secrets of shooting with photoflash" consist of practical technical advice for beginners. But within the rhetoric of his "secrets" there lie cogent and subtle reflections on the relation of light to darkness, especially on the way the flash of light makes darkness visible. In Weegee’s account, the photoflash gives photography the power of writing—writing with light, a mode of picturing uniquely suited to recording instants of life on city streets at night.

  3. Biliary cholesterol secretion : More than a simple ABC

    NARCIS (Netherlands)

    Dikkers, Arne; Tietge, Uwe J. F.

    2010-01-01

    Biliary cholesterol secretion is a process important for 2 major disease complexes, atherosclerotic cardiovascular disease and cholesterol gallstone disease With respect to cardiovascular disease, biliary cholesterol secretion is regarded as the final step for the elimination of cholesterol

  4. 5 CFR 1312.26 - Control of secret and confidential material.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Control of secret and confidential... Accountability of Classified Information § 1312.26 Control of secret and confidential material. Classified... Document Control, will be used to establish accountability controls on all Secret material received or...

  5. Secret quality of love.

    Science.gov (United States)

    Strachan-Hall, Elaine

    2016-09-01

    Many of us can recite three Donabedian dimensions of the quality of care of structure, process and outcome. Recently, I was introduced to another of Avedis Donabedian's quotes about the 'secret quality of love'.

  6. Vote Markets, Latent Opportunism, and the Secret Ballot

    DEFF Research Database (Denmark)

    Justesen, Mogens Kamp; Bøttkjær, Louise Thorn; Gates, Scott

    The secret ballot is a cornerstone of modern democracy because it protects voter autonomy and allows voters to express their political preferences freely without fear of repercussions. In theory, the secret ballot is supposed to prevent vote buying – the exchange of votes for money or material...... goods – from operating during elections. Yet, empirical evidence from surveys around the world suggests that vote buying is a common feature of elections in new democracies. Indeed, a fundamental puzzle concerns why political parties use vote buying to mobilize electoral support when the secret ballot...... allows voters to renege on their commitments and vote as they please. In this paper, we address this puzzle by arguing that voter perceptions of ballot secrecy affect their responses to vote buying offers. Theoretically, we develop a game theoretical model, where voter beliefs in the secret ballot guide...

  7. 78 FR 9945 - Sunshine Act Meeting of the National Museum and Library Services Board

    Science.gov (United States)

    2013-02-12

    ... Library Services. 1800 M Street, NW., 9th Floor, Washington, DC, 20036. Telephone: (202) 653-4676. STATUS..., United States Code because the Board will consider information that may disclose: Trade secrets and... Events and Board Liaison, Institute of Museum and Library Services, 1800 M Street, NW., 9th Floor...

  8. Cryptanalysis of 'less short' RSA secret exponents

    NARCIS (Netherlands)

    Verheul, E.R.; Tilborg, van H.C.A.

    1997-01-01

    In some applications of RSA, it is desirable to have a short secret exponent d. Wiener [6], describes a technique to use continued fractions (CF) in a cryptanalytic attack on an RSA cryptosystem having a ‘short’ secret exponent. Let n=p¿·¿q be the modulus of the system. In the typical case that

  9. Measurement of secretion in nasal lavage

    DEFF Research Database (Denmark)

    Bisgaard, H; Krogsgaard, O W; Mygind, N

    1987-01-01

    1. The amount of admixture in nasal lavage fluids was determined by addition of 99mTc labelled albumin, providing a correction factor for measurements of cellular material and humoral substances in nasal lavage return as well as a quantitative measure of nasal secretions. 2. Albumin was chosen...... secretion to be carried out on the whole sample of lavage fluid, thereby avoiding the necessity of complete admixture between marker and lavage fluid which would be pertinent to marker molecules measured chemically. The radiation from a nasal lavage is minimal and the procedure is fully acceptable...... of the nose, yet not the oropharynx. 5. A dose related increase in nasal secretion harvested by the nasal lavage in 10 persons challenged with histamine chloride could be demonstrated by this technique. 6. It is concluded that the use of 99mTc-albumin in a nasal washing provides a safe, simple and quick...

  10. Apical secretion of apolipoproteins from enterocytes

    DEFF Research Database (Denmark)

    Danielsen, E M; Hansen, Gert Helge; Poulsen, Mona Dam

    1993-01-01

    Synthesis and secretion of apolipoproteins in pig small intestine was studied by pulse-chase labeling of jejunal segments, kept in organ culture. Apo A-1 and apo B-48 were the two major proteins released, constituting 25 and 10%, respectively, of the total amount of labeled protein in the mucosal...... in the soluble fraction, suggesting a basolateral secretion into the intercellular space, and both this accumulation and the release to the medium was prevented by culture at 20 degrees C. The specific radioactivity of apo A-1 and apo B-48 released to the medium was significantly higher than...... that enterocytes release most of their newly made free apo A-1 and a significant portion of apo B-48 by exocytosis via the brush border membrane into the intestinal lumen. Fat absorption reduced apolipoprotein secretion to the medium and induced the formation of chylomicrons, containing apo A-1 at their surface...

  11. Human placenta secretes apolipoprotein B-100-containing lipoproteins

    DEFF Research Database (Denmark)

    Munk-Madsen, Eva; Lindegaard, Marie Louise Skakkebæk; Andersen, Claus B

    2004-01-01

    Supply of lipids from the mother is essential for fetal growth and development. In mice, disruption of yolk sac cell secretion of apolipoprotein (apo) B-containing lipoproteins results in embryonic lethality. In humans, the yolk sac is vestigial. Nutritional functions are instead established very...... lipoproteins secreted from placental tissue showed spherical particles with a diameter of 47 +/- 10 nm. These results demonstrate that human placenta expresses both apoB and MTP and consequently synthesize and secrete apoB-100-containing lipoproteins. Placental lipoprotein formation constitutes a novel pathway...

  12. Ranitidine has no influence on tubular creatinine secretion

    NARCIS (Netherlands)

    van den Berg, J. G.; Koopman, M. G.; Arisz, L.

    1996-01-01

    Oral cimetidine competitively inhibits tubular secretion of creatinine. We investigated the potential of oral ranitidine, a comparable H2-receptor antagonist, to block tubular creatinine secretion. In 10 healthy subjects, clearances of inulin and endogenous creatinine were simultaneously measured

  13. Monitoring external and internal loads of brazilian soccer referees during official matches.

    Science.gov (United States)

    Costa, Eduardo C; Vieira, Caio M A; Moreira, Alexandre; Ugrinowitsch, Carlos; Castagna, Carlo; Aoki, Marcelo S

    2013-01-01

    This study aimed to assess the external and internal loads of Brazilian soccer referees during official matches. A total of 11 field referees (aged 36.2 ± 7.5 years) were monitored during 35 matches. The external (distance covered, mean and maximal speed) and internal load parameters (session ratings of perceived exertion [RPE] training load [TL], Edwards' TL, and time spent in different heart rate [HR] zones) were assessed in 3-4 matches per referee. External load parameters were measured using a wrist Global Positioning System (GPS) receiver. No differences in distance covered (5.219 ± 205 vs. 5.230 ± 237 m) and maximal speed (19.3 ± 1.0 vs. 19.4 ± 1.4 km·h(-1)) were observed between the halves of the matches (p > 0.05). However, the mean speed was higher in the first half of the matches (6.6 ± 0.4 vs. 6.4 ± 0.3 km·h(-1)) (p external and internal load demands during official matches. The portable GPS/HR monitors and session RPE method can provide relevant information regarding the magnitude of the physiological strain during official matches. Key PointsHigh external and internal loads were imposed on Brazilian soccer referees during official matches.There was a high positive correlation between a subjective marker of internal load (session RPE) and parameters of external load (distance covered between 90-100% of HRmax and maximal speed).There was a high positive correlation between session RPE method and Edwards' method.Session RPE seems to be a reliable marker of internal load.The portable GPS/HR monitors and the session RPE method can provide relevant information regarding the magnitude of external and internal loads of soccer referees during official matches.

  14. TimeSet: A computer program that accesses five atomic time services on two continents

    Science.gov (United States)

    Petrakis, P. L.

    1993-01-01

    TimeSet is a shareware program for accessing digital time services by telephone. At its initial release, it was capable of capturing time signals only from the U.S. Naval Observatory to set a computer's clock. Later the ability to synchronize with the National Institute of Standards and Technology was added. Now, in Version 7.10, TimeSet is able to access three additional telephone time services in Europe - in Sweden, Austria, and Italy - making a total of five official services addressable by the program. A companion program, TimeGen, allows yet another source of telephone time data strings for callers equipped with TimeSet version 7.10. TimeGen synthesizes UTC time data strings in the Naval Observatory's format from an accurately set and maintained DOS computer clock, and transmits them to callers. This allows an unlimited number of 'freelance' time generating stations to be created. Timesetting from TimeGen is made feasible by the advent of Becker's RighTime, a shareware program that learns the drift characteristics of a computer's clock and continuously applies a correction to keep it accurate, and also brings .01 second resolution to the DOS clock. With clock regulation by RighTime and periodic update calls by the TimeGen station to an official time source via TimeSet, TimeGen offers the same degree of accuracy within the resolution of the computer clock as any official atomic time source.

  15. 29 CFR 801.75 - Certification of official record.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Certification of official record. 801.75 Section 801.75 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR OTHER LAWS... Decision and Order issued under this part, the Chief Administrative Law Judge shall promptly certify and...

  16. Research on the Achievement Motivation of the University Student Village Officials in the Suburbs of Beijing

    Institute of Scientific and Technical Information of China (English)

    YANG Xin

    2011-01-01

    [Objective] The aim was to explore the achievement motivation of the university student village officials in the suburbs of Beijing.[Method] The research made an investigation on 429 university student village officials in the suburbs of Beijing by the Achievements Motive Scale (AMS). [ Result] The achievement motivation of these student village officials was not on a high level, but they tended to pursue the success motivation rather than the motivation to avoid failures obviously. There was a significant difference in the achievement motivation between different genders, majors and jobs. The males' motivation for success was higher than the females'. The motivation of avoiding failures among officials in Humanities was higher than in Science and in Fine Art. And the university student village officials in professional and technical posts or in business posts rated the motivation to avoid failures more important than in basic management posts. But achievement motivations in different urban-rural areas, educational levels, political backgrounds, whether student leaders or not, and durations were no definite differences. Besides, it had a significant effect on these student village officials' achievement motivation whether advices and suggestions were accepted; if yes,the motivation was higher. [ Conclusion] This study had provided stability and development for building rural talent groups.

  17. Overexpressing key component genes of the secretion pathway for enhanced secretion of an Aspergillus niger glucose oxidase in Trichoderma reesei.

    Science.gov (United States)

    Wu, Yilan; Sun, Xianhua; Xue, Xianli; Luo, Huiying; Yao, Bin; Xie, Xiangming; Su, Xiaoyun

    2017-11-01

    Vast interest exists in developing T. reesei for production of heterologous proteins. Although rich genomic and transcriptomic information has been uncovered for the T. reesei secretion pathway, little is known about whether engineering its key components could enhance expression of a heterologous gene. In this study, snc1, a v-SNARE gene, was first selected for overexpression in T. reesei. In engineered T. reesei with additional copies of snc1, the Aspergillus niger glucose oxidase (AnGOD) was produced to a significantly higher level (2.2-fold of the parental strain). hac1 and bip1, two more component genes in the secretion pathway, were further tested for overexpression and found to be also beneficial for AnGOD secretion. The overexpression of one component gene more or less affected the expression of the other two genes, suggesting a complex regulating mechanism. Our study demonstrates the potential of engineering the secretion pathway for enhancing heterologous gene production in T. reesei. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Official dosimetry with individual electronic dosemeters - the concept in Germany

    International Nuclear Information System (INIS)

    Czarwinski, R.; Kaulard, J.; Pfeffer, W.

    2005-01-01

    Full text: Presently, in Germany passive dosemeters (film batches, RPL, TLD) are used for the official individual monitoring of occupational exposed personal. The application of electronic individual dosemeters (EPD) is carried out mainly for the operative radiation protection control particularly in nuclear power engineering companies, big hospitals und research centres. This means in such institutions double monitoring exists - legally and operatively. A crucial advantage of EPD compared to passive dosemeter is the possibility to adapt the monitoring period to the working time in the control area, e.g. a job related monitoring is available. Germany started a project for an optimized implementation of EPD into the official dosimetry. Objective of the project whose results will be described in the paper is the harmonization of radiation protection of companies workers and outside workers concerning the record of individual and job related exposures. The approval of the EPD by the Federal and Laender authorities as an official dosimetric system demands the implementation of special requirements concerning the data acquisition, data transfer and data evaluation. These issues are focuses of the Federal research project, supervised by the Federal Office for Radiation Protection (BfS) and performed by the Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS), Cologne to develop a concept in the first stage. (author)

  19. Optimal Black-Box Secret Sharing over Arbitrary Abelian Groups

    DEFF Research Database (Denmark)

    Cramer, Ronald; Fehr, Serge

    2002-01-01

    A black-box secret sharing scheme for the threshold access structure T t,n is one which works over any finite Abelian group G. Briefly, such a scheme differs from an ordinary linear secret sharing scheme (over, say, a given finite field) in that distribution matrix and reconstruction vectors...... are defined over ℤ and are designed independently of the group G from which the secret and the shares are sampled. This means that perfect completeness and perfect privacy are guaranteed regardless of which group G is chosen. We define the black-box secret sharing problem as the problem of devising......, for an arbitrary given T t,n , a scheme with minimal expansion factor, i.e., where the length of the full vector of shares divided by the number of players n is minimal. Such schemes are relevant for instance in the context of distributed cryptosystems based on groups with secret or hard to compute group order...

  20. Threshold secret sharing scheme based on phase-shifting interferometry.

    Science.gov (United States)

    Deng, Xiaopeng; Shi, Zhengang; Wen, Wei

    2016-11-01

    We propose a new method for secret image sharing with the (3,N) threshold scheme based on phase-shifting interferometry. The secret image, which is multiplied with an encryption key in advance, is first encrypted by using Fourier transformation. Then, the encoded image is shared into N shadow images based on the recording principle of phase-shifting interferometry. Based on the reconstruction principle of phase-shifting interferometry, any three or more shadow images can retrieve the secret image, while any two or fewer shadow images cannot obtain any information of the secret image. Thus, a (3,N) threshold secret sharing scheme can be implemented. Compared with our previously reported method, the algorithm of this paper is suited for not only a binary image but also a gray-scale image. Moreover, the proposed algorithm can obtain a larger threshold value t. Simulation results are presented to demonstrate the feasibility of the proposed method.