[Urban ecological risk assessment: a review].

Science.gov (United States)

Wang, Mei-E; Chen, Wei-Ping; Peng, Chi

2014-03-01

With the development of urbanization and the degradation of urban living environment, urban ecological risks caused by urbanization have attracted more and more attentions. Based on urban ecology principles and ecological risk assessment frameworks, contents of urban ecological risk assessment were reviewed in terms of driven forces, risk resources, risk receptors, endpoints and integrated approaches for risk assessment. It was suggested that types and degrees of urban economical and social activities were the driven forces for urban ecological risks. Ecological functional components at different levels in urban ecosystems as well as the urban system as a whole were the risk receptors. Assessment endpoints involved in changes of urban ecological structures, processes, functional components and the integrity of characteristic and function. Social-ecological models should be the major approaches for urban ecological risk assessment. Trends for urban ecological risk assessment study should focus on setting a definite protection target and criteria corresponding to assessment endpoints, establishing a multiple-parameter assessment system and integrative assessment approaches.

Site-specific probabilistic ecological risk assessment of a volatile chlorinated hydrocarbon-contaminated tidal estuary.

Science.gov (United States)

Hunt, James; Birch, Gavin; Warne, Michael St J

2010-05-01

Groundwater contaminated with volatile chlorinated hydrocarbons (VCHs) was identified as discharging to Penrhyn Estuary, an intertidal embayment of Botany Bay, New South Wales, Australia. A screening-level hazard assessment of surface water in Penrhyn Estuary identified an unacceptable hazard to marine organisms posed by VCHs. Given the limitations of hazard assessments, the present study conducted a higher-tier, quantitative probabilistic risk assessment using the joint probability curve (JPC) method that accounted for variability in exposure and toxicity profiles to quantify risk (delta). Risk was assessed for 24 scenarios, including four areas of the estuary based on three exposure scenarios (low tide, high tide, and both low and high tides) and two toxicity scenarios (chronic no-observed-effect concentrations [NOEC] and 50% effect concentrations [EC50]). Risk (delta) was greater at low tide than at high tide and varied throughout the tidal cycle. Spatial distributions of risk in the estuary were similar using both NOEC and EC50 data. The exposure scenario including data combined from both tides was considered the most accurate representation of the ecological risk in the estuary. When assessing risk using data across both tides, the greatest risk was identified in the Springvale tributary (delta=25%)-closest to the source area-followed by the inner estuary (delta=4%) and the Floodvale tributary (delta=2%), with the lowest risk in the outer estuary (delta=0.1%), farthest from the source area. Going from the screening level ecological risk assessment (ERA) to the probabilistic ERA changed the risk from unacceptable to acceptable in 50% of exposure scenarios in two of the four areas within the estuary. The probabilistic ERA provided a more realistic assessment of risk than the screening-level hazard assessment. Copyright (c) 2010 SETAC.

Cervical cancer risk levels in Turkey and compliance to the national cervical cancer screening standard.

Science.gov (United States)

Açikgöz, Ayla; Ergör, Gül

2011-01-01

Cervical cancer screening with Pap smear test is a cost-effective method. The Ministry of Health in Turkey recommends that it be performed once every five years after age 35. The purpose of this study was to determine the cervical cancer risk levels of women between 35 and 69, and the intervals they have the Pap smear test, and to investigate the relation between the two. This study was performed on 227 women aged between 35 and 69 living in Balçova District of İzmir province. Using the cervical cancer risk index program of Harvard School of Public Health, the cervical cancer risk level of 70% of the women was found below average, 22.1% average, and 7.9% above average. Only 52% of the women have had Pap smear test at least once in their lives. The percentage screening regularly in conformity with the national screening standard was 39.2%. Women in the 40-49 age group, were married, conformed significantly more (pducation and decreased with the cervical cancer risk level (pducation level, menstruation state of the women and the economic level of the family. Not having the Pap smear test in conformity with the national cervical cancer screening standard in 35-39 age group was 2.52 times more than 40-49 age group, while it was 3.26 times more in 60-69 age group (pducation level might cause not having Pap smear test. Under these circumstances, the cervical cancer risk levels should be determined and the individuals should be informed. Providing Pap smear test screening service to individuals in the target group of national screening standard, as a public service may resolve the inequalities due to age and educational differences.

Ecologic and Sociodemographic Risk Determinants for Dengue Transmission in Urban Areas in Thailand

Directory of Open Access Journals (Sweden)

Surachart Koyadun

2012-01-01

Full Text Available This study analyzed the association between household-level ecologic and individual-level sociodemographic determinants and dengue transmission in urban areas of Chachoengsao province, Thailand. The ecologic and sociodemographic variables were examined by univariate analysis and multivariate logistic regression. In the ecologic model, dengue risk was related to households situated in the ecotope of residential mixed with commercial and densely populated urban residential areas (RCDENPURA (aOR = 2.23, , high historical dengue risk area (aOR = 2.06, , and presence of household window screens (aOR = 1.62, . In the sociodemographic model, the dengue risk was related to householders aged >45 years (aOR = 3.24, , secondary and higher educational degrees (aOR = 2.33, , household members >4 persons (aOR = 2.01, , and community effort in environmental management by clean-up campaign (aOR = 1.91, . It is possible that the preventive measures were positively correlated with dengue risk because these activities were generally carried out in particular households or communities following dengue experiences or dengue outbreaks. Interestingly, the ecotope of RCDENPURA and high historical dengue risk area appeared to be very good predictors of dengue incidences.

A framework for assessing ecological risks of petroleum-derived materials in soil

International Nuclear Information System (INIS)

Suter, G.W. II

1997-05-01

Ecological risk assessment estimates the nature and likelihood of effects of human actions on nonhuman organisms, populations, and ecosystems. It is intended to be clearer and more rigorous in its approach to estimation of effects and uncertainties than previously employed methods of ecological assessment. Ecological risk assessment is characterized by a standard paradigm that includes problem formulation, analysis of exposure and effects, risk characterization, and communication with a risk manager. This report provides a framework that applies the paradigm to the specific problem of assessing the ecological risks of petroleum in soil. This type of approach requires that assessments be performed in phases: (1) a scoping assessment to determine whether there is a potential route of exposure for potentially significant ecological receptors; (2) a screening assessment to determine whether exposures could potentially reach toxic levels; and (3) a definitive assessment to estimate the nature, magnitude, and extent of risks. The principal technical issue addressed is the chemically complex nature of petroleum--a complexity that may be dealt with by assessing risks on the basis of properties of the whole material, properties of individual chemicals that are representative of chemical classes, distributions of properties of the constituents of chemical classes, properties of chemicals detected in the soil, and properties of indicator chemicals. The advantages and feasibility of these alternatives are discussed. The report concludes with research recommendations for improving each stage in the assessment process

Applications of contaminant fate and bioaccumulation models in assessing ecological risks of chemicals: A case study for gasoline hydrocarbons

Energy Technology Data Exchange (ETDEWEB)

MacLeod, Matthew; McKone, Thomas E.; Foster, Karen L.; Maddalena, Randy L.; Parkerton, Thomas F.; Mackay, Don

2004-02-01

Mass balance models of chemical fate and transport can be applied in ecological risk assessments for quantitative estimation of concentrations in air, water, soil and sediment. These concentrations can, in turn, be used to estimate organism exposures and ultimately internal tissue concentrations that can be compared to mode-of-action-based critical body residues that correspond to toxic effects. From this comparison, risks to the exposed organism can be evaluated. To illustrate the practical utility of fate models in ecological risk assessments of commercial products, the EQC model and a simple screening level biouptake model including three organisms, (a bird, a mammal and a fish) is applied to gasoline. In this analysis, gasoline is divided into 24 components or ''blocks'' with similar environmental fate properties that are assumed to elicit ecotoxicity via a narcotic mode of action. Results demonstrate that differences in chemical properties and mode of entry into the environment lead to profound differences in the efficiency of transport from emission to target biota. We discuss the implications of these results and insights gained into the regional fate and ecological risks associated with gasoline. This approach is particularly suitable for assessing mixtures of components that have similar modes of action. We conclude that the model-based methodologies presented are widely applicable for screening level ecological risk assessments that support effective chemicals management.

Screening effects on thyroid cancer risk estimates for populations affected by the Chernobyl accident

International Nuclear Information System (INIS)

Jacob, P.; Kaiser, J. C.; Vavilov, S.E.; Bogdanova, T.; Tronko, N. D.

2004-01-01

Simulation calculations are performed in order to explore the ecological bias in studies as they are performed with settlement specific data in the aftemath of the Chernobyl accident. Based on methods, that were developed by Lubin for exploring the ecologic bias due to smoking in indoor radon studies of lung cancer, the influence of the introduction of ultrasound devices and enhanced medical surveillance on the detection and reporting of thyroid cancer cases was investigated. Calculations were performed by simulating thyroid doses of one million children in a total of 744 settlements and assuming a linear dependence of the risk on dose and various scenarios of the screening. The dose distributions simulate the distributions similar to those used in previous ecologic studies of the thyroid cancer risk in Ukraine after the Chernobyl accident. The ecologic bias was defined as the ratio of risk coefficients derived from an ecological study to the corresponding risk factor in the underlying risl model. the ecologic bias was estimated for each of the screening scenarios. Analytical equations were derived that allow the exact numerical compuation of the bias which is determined by covariance terms between the increased detection and reporting on one side and thyroid dose values (individual and averaged for the settlements) on the other side. Nested in th epopulation data, a cohort study was simulated with 10 000 individuals and an average thyroid dose of 0.3 Gy. the present study underlines the different scopes of the ecologic and cohort study designs perfomed in the aftermed of the Chernobyl accident. Whereas the ecologic studies give an estimate of the excess thyroid cancer risks per unit dose under the conditions of a health care system as it is typical for the affected countries after the Chernobyl accident, the cohort study gives risk estimates within a well screened cohort. Due to the strong screening effects, excess absoulte risks in the ecological study cohort are

Screening Risk Evaluation methodology

International Nuclear Information System (INIS)

Hopper, K.M.

1994-01-01

The Screening Risk Evaluation (SRE) Guidance document is a set of guidelines provided for the uniform implementation of SREs performed on D ampersand D facilities. These guidelines are designed specifically for the completion of the second (semi-quantitative screening) phase of the D ampersand D Risk-Based Process. The SRE Guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the risk to human health and the environment from ongoing or probable releases within a one year time period. The Worker Exposure Index (WEI) calculates the risk to workers, occupants, and visitors in D ampersand D facilities of contaminant exposure. The Future Release Index (FRI) calculates the risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risk-to human health due to factors other than that of contaminants. The index of Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, determined on a project by project basis. The SRE is the first and most important step in the overall D ampersand D project level decision making process

Ecological risk assessment of deep geological disposal of high-level nuclear waste

International Nuclear Information System (INIS)

Hart, D.R.; Lush, D.L.; Acton, D.W.

1993-01-01

Contaminant fate and transport models, radiological dosimetry models, chemical dose-response models and population dynamic models were used to estimate ecological risks to moose and brook trout populations arising from a proposed high-level nuclear waste repository. Risks from potential contaminant releases were compared with risks from physical habitat alteration in constructing a repository and service community, and with risks from increased hunting and fish pressure in the area. For a reference environment typical of a proposed location somewhere in the Canadian Shield, preliminary results suggest that the population consequences of contaminant release will be minor relative to those of habitat alteration and natural resource use

Use of screening action levels in risk management at Los Alamos National Laboratory

International Nuclear Information System (INIS)

Beck, J.R.; Hueske, K.L.; Dorries, A.M.

1994-01-01

The screening assessment approach used at Los Alamos National Laboratory has proved to be a valuable risk management tool in making decisions that are cost-effective, efficient, and defensible. Los Alamos has successfully used screening action levels to prioritize RFI activities, streamline data evaluation, and insure analytical methods are adequately sensitive to be protective of human health

The pros and cons of ecological risk assessment based on data from different levels of biological organization

Science.gov (United States)

Rohr, Jason R.; Salice, Christopher J.; Nisbet, Roger M.

2016-01-01

Ecological risk assessment (ERA) is the process used to evaluate the safety of manufactured chemicals to the environment. Here we review the pros and cons of ERA across levels of biological organization, including suborganismal (e.g. biomarkers), individual, population, community, ecosystem, and landscapes levels. Our review revealed that level of biological organization is often related negatively with ease at assessing cause-effect relationships, ease of high-throughput screening of large numbers of chemicals (it is especially easier for suborganismal endpoints), and uncertainty of the ERA because low levels of biological organization tend to have a large distance between their measurement (what is quantified) and assessment endpoints (what is to be protected). In contrast, level of biological organization is often related positively with sensitivity to important negative and positive feedbacks and context dependencies within biological systems, and ease at capturing recovery from adverse contaminant effects. Some endpoints did not show obvious trends across levels of biological organization, such as the use of vertebrate animals in chemical testing and ease at screening large numbers of species, and other factors lacked sufficient data across levels of biological organization, such as repeatability, variability, cost per study, and cost per species of effects assessment, the latter of which might be a more defensible way to compare costs of ERAs than cost per study. To compensate for weaknesses of ERA at any particular level of biological organization, we also review mathematical modeling approaches commonly used to extrapolate effects across levels of organization. Finally, we provide recommendations for next generation ERA, submitting that if there is an ideal level of biological organization to conduct ERA, it will only emerge if ERA is approached simultaneously from the bottom of biological organization up as well as from the top down, all while employing

The pros and cons of ecological risk assessment based on data from different levels of biological organization.

Science.gov (United States)

Rohr, Jason R; Salice, Christopher J; Nisbet, Roger M

2016-10-01

Ecological risk assessment (ERA) is the process used to evaluate the safety of manufactured chemicals to the environment. Here we review the pros and cons of ERA across levels of biological organization, including suborganismal (e.g., biomarkers), individual, population, community, ecosystem and landscapes levels. Our review revealed that level of biological organization is often related negatively with ease at assessing cause-effect relationships, ease of high-throughput screening of large numbers of chemicals (it is especially easier for suborganismal endpoints), and uncertainty of the ERA because low levels of biological organization tend to have a large distance between their measurement (what is quantified) and assessment endpoints (what is to be protected). In contrast, level of biological organization is often related positively with sensitivity to important negative and positive feedbacks and context dependencies within biological systems, and ease at capturing recovery from adverse contaminant effects. Some endpoints did not show obvious trends across levels of biological organization, such as the use of vertebrate animals in chemical testing and ease at screening large numbers of species, and other factors lacked sufficient data across levels of biological organization, such as repeatability, variability, cost per study and cost per species of effects assessment, the latter of which might be a more defensible way to compare costs of ERAs than cost per study. To compensate for weaknesses of ERA at any particular level of biological organization, we also review mathematical modeling approaches commonly used to extrapolate effects across levels of organization. Finally, we provide recommendations for next generation ERA, submitting that if there is an ideal level of biological organization to conduct ERA, it will only emerge if ERA is approached simultaneously from the bottom of biological organization up as well as from the top down, all while employing

Ecological risk estimation

International Nuclear Information System (INIS)

Bartell, S.M.; Gardner, R.H.; O'Neill, R.V.

1992-01-01

Ecological risk assessment, the process that evaluates the likelihood that adverse ecological effects may occur or are occurring as a result of exposure to one or more stressors, is being developed by the US EPA as a tool for decision making. This book presents one approach to risk assessment-that of applying laboratory toxicity data within an ecosystem model to predict the potential ecological consequences of toxic chemicals. Both Standard Water Column Model (SWACOM), using zooplankton and fish, and Monte Carlo simulations are discussed in detail, along with quantitative explanations for many responses. Simplifying assumptions are explicitly presented. The final chapter discusses strengths, weaknesses, and future directions of the approach. The book is appropriate for anyone who does or uses ecological risk assessment methodologies

Prevalence of coronary heart disease risk factors and screening for high cholesterol levels among young adults, United States, 1999-2006.

Science.gov (United States)

Kuklina, Elena V; Yoon, Paula W; Keenan, Nora L

2010-01-01

Previous studies have reported low rates of screening for high cholesterol levels among young adults in the United States. Although recommendations for screening young adults without risk factors for coronary heart disease (CHD) differ, all guidelines recommend screening adults with CHD, CHD equivalents, or 1 or more CHD risk factors. This study examined national prevalence of CHD risk factors and compliance with the cholesterol screening guidelines among young adults. National estimates were obtained using results for 2,587 young adults (men aged 20 to 35 years; women aged 20 to 45 years) from the 1999-2006 National Health and Nutrition Examination Surveys. We defined high low-density lipoprotein cholesterol (LDL-C) as levels higher than the goal specific for each CHD risk category outlined in the National Cholesterol Education Program Adult Treatment Panel III guidelines. About 59% of young adults had CHD or CHD equivalents, or 1 or more of the following CHD risk factors: family history of early CHD, smoking, hypertension, or obesity. In our study, the overall screening rate in this population was less than 50%. Moreover, no significant difference in screening rates between young adults with no risk factors and their counterparts with 1 or more risk factors was found even after adjustment for sociodemographic and health care factors. Approximately 65% of young adults with CHD or CHD equivalents, 26% of young adults with 2 or more risk factors, 12% of young adults with 1 risk factor, and 7% with no risk factor had a high level of LDL-C. CHD risk factors are common in young adults but do not appear to alter screening rates. Improvement of risk assessment and management for cardiovascular disease among young adults is warranted.

[Ecological risk assessment of Taihu Lake basin based on landscape pattern].

Science.gov (United States)

Xie, Xiao Ping; Chen, Zhi Cong; Wang, Fang; Bai, Mao Wei; Xu, Wen Yang

2017-10-01

Taihu Lake basin was selected as the study site. Based on the landscape data of 2000, 2005, 2010 and 2015, the Markov and CLUE-S models were used to simulate the landscape types with different scenarios in 2030, and landscape ecological risk index was constructed. The shift of gravity center and spatial statistics were used to reveal landscape ecological risk of Taihu Lake basin with temporal and spatial characteristics. The results showed that the ecological risk mainly was at medium and low levels in Taihu Lake basin, and the higher ecological risk areas were mainly distributed at the Taihu Lake area during 2000 to 2015, and the low ecological risk was transferred from the southwest and south of Taihu Lake to the developed areas in the northern part of Taihu Lake area. Spatial analysis showed that landscape ecological risk had negative correlation with natural factors, which was weakened gradually, while the correlation with socioeconomic factors trended to become stronger, with human disturbance affecting the landscape ecological risk significantly. The impact of socioeconomic factors on landscape ecological risks differed in different urbanization stages. In the developing area, with the economic development, the landscape was increasingly fragmented and the ecological risk was correspondingly increased. While in the developed area, with the further development of the economy, the aggregation index was increased, and fragmentation and separation indexes were decreased, ecological construction was restored, and the landscape ecological risk began to decline. CLUE-S model simulation showed that the ecological risk of Taihu Lake basin would be reduced in future, mainly on the low and relatively low levels. Taihu Lake area, both in history and the future, is a high ecological risk zone, and its management and protection should be strengthened.

Ecological risk assessment at the Idaho National Engineering Laboratory: Overview

International Nuclear Information System (INIS)

VanHorn, R.; Bensen, T.; Green, T.; Hampton, N.; Staley, C.; Morris, R.; Brewer, R.; Peterson, S.

1994-01-01

The paper will present an overview of the methods and results of the screening level ecological risk assessment (ERA) performed at the Idaho National Engineering Laboratory (INEL). The INEL is a site with some distinct characteristics. First it is a large Department of Energy (DOE) laboratory (2,300 km 2 ) having experienced 40 years of nuclear material production operations. Secondly, it is a relatively undisturbed cold desert ecosystem. Neither of these issues have been sufficiently addressed in previous ERAs. It was necessary in many instances to develop methods that differed from those used in other studies. This paper should provide useful methodologies for the ERAs performed at other similar sites

Ecological Risk Assessment of Jarosite Waste Disposal

Directory of Open Access Journals (Sweden)

Mihone Kerolli-Mustafa

2015-07-01

Full Text Available Jarosite waste, originating from zinc extraction industry, is considered hazardous due to the presence and the mobility of toxic metals that it contains. Its worldwide disposal in many tailing damps has become a major ecological concern. Three different methods, namely modified Synthetic Precipitation Leaching Procedure (SPLP, three-stage BCR sequential extraction procedure and Potential Ecological Risk Index (PERI Method were used to access the ecological risk of jarosite waste disposal in Mitrovica Industrial Park, Kosovo. The combination of these methods can effectively identify the comprehensive and single pollution levels of heavy metals such as Zn, Pb, Cd, Cu, Ni and As present in jarosite waste. Moreover, the great positive relevance between leaching behavior of heavy metals and F1 fraction was supported by principal component analysis (PCA. PERI results indicate that Cd showed a very high risk class to the environment. The ecological risk of heavy metals declines in the following order: Cd>Zn>Cu>Pb>Ni>As.

Concentration Levels, Pollution Characteristics and Potential Ecological Risk of Dust Heavy Metals in the Metropolitan Area of Beijing, China.

Science.gov (United States)

Xiong, Qiulin; Zhao, Wenji; Zhao, Jiayin; Zhao, Wenhui; Jiang, Lei

2017-09-30

This study aims to investigate the concentration levels, pollution characteristics and the associated potential ecological risks of the heavy metals found in dust in the metropolitan area of Beijing, China during the winter. Dust samples were collected at 49 different spatial locations of Beijing's metropolitan area from November 2013 to January 2014, in which the concentration levels of Cd, Cr, Pb, Cu, Zn, Ni, Co, V, Bi and Mo were measured by Elan DRC II type inductively coupled plasma mass spectrometry (ICP-MS). Test results showed that the concentrations of dust heavy metals Pb, Cr, Cu and Zn in the urban areas (147.1 mg·kg -1 , 195.9 mg·kg -1 , 239.2 mg·kg -1 and 713.2 mg·kg -1 ) were significantly higher than those in the suburbs (91.6 mg·kg -1 , 125.1 mg·kg -1 , 131.9 mg·kg -1 and 514.5 mg·kg -1 ). Enrichment factors and the geo-accumulation index were used to describe the pollution characteristics of dust heavy metals in urban and suburban areas. Results indicated that Zn and Cu were moderately polluting in both urban and suburban areas, Cd was severely polluting in urban areas and heavily polluting in the suburbs. Furthermore, potential ecological risk assessment revealed that the degrees of ecological harm of dust heavy metals were very strong in both urban and suburban areas, but especially in urban areas. The potential ecological risk of heavy metal Cd, whose single factor of ecological damage was extremely strong, accounted for about 90% of the total ecological risk.

A case study for evaluating ecological risks at the Idaho National Engineering Laboratory (INEL)

International Nuclear Information System (INIS)

Peterson, S.; Brewer, R.; Morris, R.; VanHorn, R.

1994-01-01

A case study was conducted as a component of the development of guidance for ecological risk assessment at the Department of Energy's Idaho National Engineering Laboratory (INEL). The INEL is a large facility in southeastern Idaho, encompassing expanses of sagebrush-steppe that harbor numerous wildlife species. Nuclear research and waste disposal activities have resulted in releases of radionuclides at various sites. Due to the size and number of potentially contaminated areas, a cost-effective method was needed to evaluate ecological risks and to identify data needs for remedial investigations. Screening-level assessment approaches were developed to evaluate data collected from previous site investigations. Above-background concentrations of radionuclides and other contaminants in media were compared to risk-based criteria, which were derived from sources such as recent publications of the International Atomic Energy Agency (IAEA) and National Council on Radiation Protection and Measurements (NCRP). Site-specific risks to plants and wildlife were estimated for contaminants exceeding criteria. Dose rates derived using various estimation methods were compared to reference doses for wildlife obtained from IAEA, NCRP, and other publications

Toward effective ecological risk-management of refinery corrective action

International Nuclear Information System (INIS)

Metzger, B.H.; Rury, P.M.; Turton, D.; Archibald, B.; Clark, J.; Cura, J.

1995-01-01

Cleanup of complex industrial sites, such as refineries, requires risk-based decision tools to ensure that environmentally protective remediation is consistent with current and future land use. However, conventional ecological risk assessment approaches are not well suited for complex industrial sites. Site risk assessments focus on hypothetical chemical risk assuming diverse and undisturbed ecosystems, rather than industrial and disturbed area conditions. In addition, they offer little guidance as to how to make timely and effective risk management decisions. An innovative methodology is proposed to assist industry and regulatory risk managers with rapid EcoRisk reconnaissance and cost-effective remedial decision-making at complex industrial sites. Phase 1 comprises a three-step risk screening of areas of ecological concern at the site, which integrates habitat quality characteristics and potential chemical hazards. It yields an ordering of areas as follows: areas of no significant risk; areas of potentially significant risk; and areas of likely significant risk. A decision rule is then applied to determine appropriate risk management action, including: no action; additional study; and remedial or management action. In Phase 2, additional study is conducted for areas that exhibit potentially significant risk so as to facilitate risk management. This methodology is currently being applied at the 1,300 acre, former Exxon Bayway Refinery in New Jersey

PROJECTING POPULATION-LEVEL RESPONSE OF PURPLE SEA URCHINS TO LEAD CONTAMINATION FOR AN ESTUARINE ECOLOGICAL RISK ASSESSMENT

Science.gov (United States)

As part of an ecological risk assessment case study at the Portsmouth naval Shipyard (PNS), Kittery, Maine, USA, the population level effects of lead exposure to purple sea urchin, Arbacia punctulata, were investigated using a stage-classified matrix population model. The model d...

Organochlorine pesticides across the tributaries of River Ravi, Pakistan: Human health risk assessment through dermal exposure, ecological risks, source fingerprints and spatio-temporal distribution.

Science.gov (United States)

Baqar, Mujtaba; Sadef, Yumna; Ahmad, Sajid Rashid; Mahmood, Adeel; Li, Jun; Zhang, Gan

2018-03-15

This study monitored the human health risks through dermal exposure, hazardous risks to ecological integrity, contamination levels, spatio-temporal distribution, and congener specific analysis of organochlorine pesticides (OCPs) across River Ravi and its three northern tributaries (Nullah Bein, Nullah Basanter and Nullah Deg). The residual levels of OCPs isomers were screened for water (n=54) and surface sediment (n=54) samples from twenty seven sampling sites in two alternate seasons (pre-monsoon and post-monsoon). The ∑OCPs concentrations ranged from 13.61 to 1992.18ng/g dry weight and 12.89 to 128.16ng/L with predominance of β-endosulfan and p,p'-DDT in sediment and water matrixes, respectively. Distribution pattern revealed significantly higher concentrations in upstream and midstream, suggesting considerable transboundary OCPs pollution. Calculated ratios of α-HCH/γ-HCH, o,p'-DDT/p,p'-DDT, (DDE+DDD)/∑DDTs and cis/trans-chlordane for water and sediments identified the fresh addition of lindane, technical DDTs and chlordane in the study area. Risk quotient (RQ) based ecological risk was found to be >1 at all studied streams during both seasons and elucidates higher risks for endosulfan (α-endosulfan) and endrin. Human health risk assessment indicated absence of hazardous (non-carcinogenic) risk through bathing in studied streams; as the hazard index values ranged from 1.09E-05 to 2.48E-02 (acceptable limit; ecological risk and carcinogenic human health risk had emphasized an immediate elimination of ongoing OCPs addition in the studied area. Copyright © 2017 Elsevier B.V. All rights reserved.

A DPSIR model for ecological security assessment through indicator screening: a case study at Dianchi Lake in China.

Directory of Open Access Journals (Sweden)

Zhen Wang

Full Text Available Given the important role of lake ecosystems in social and economic development, and the current severe environmental degradation in China, a systematic diagnosis of the ecological security of lakes is essential for sustainable development. A Driving-force, Pressure, Status, Impact, and Risk (DPSIR model, combined with data screening for lake ecological security assessment was developed to overcome the disadvantages of data selection in existing assessment methods. Correlation and principal component analysis were used to select independent and representative data. The DPSIR model was then applied to evaluate the ecological security of Dianchi Lake in China during 1988-2007 using an ecological security index. The results revealed a V-shaped trend. The application of the DPSIR model with data screening provided useful information regarding the status of the lake's ecosystem, while ensuring information efficiency and eliminating multicollinearity. The modeling approach described here is practical and operationally efficient, and provides an attractive alternative approach to assess the ecological security of lakes.

Framework for ecological risk assessment

International Nuclear Information System (INIS)

Rodier, D.; Norton, S.

1992-02-01

Increased interest in ecological issues such as global climate change, habitat loss, acid deposition, reduced biological diversity, and the ecological impacts of pesticides and toxic chemicals prompts this U.S. Environmental Protection Agency (EPA) report, A Framework for Ecological Risk Assessment ('Framework Report'). The report describes basic elements, or a framework, for evaluating scientific information on the adverse effects of physical and chemical stressors on the environment. The framework offers starting principles and a simple structure as guidance for current ecological risk assessments and as a foundation for future EPA proposals for risk assessment guidelines

RBCA-based approaches to ecological risk assessment for TPH-contaminated areas

International Nuclear Information System (INIS)

Hummell, R.; Vedagiri, U.

1995-01-01

The RBCA guidelines proposed by ASTM form an evaluation and decision-making framework for sites potentially contaminated by petroleum releases. They present a three-tiered approach of decreasing conservatism and increasing site-specificity that primarily evaluates risks to human health. While RBCA includes consideration of environmental impacts, there are no specific recommendations on how this is to be achieved. A RBCA-based ecological risk assessment approach was developed for TPH-contaminated areas in Alaska. The approach presents a habitat-based selection process for surrogate chemicals and indicator chemicals of ecological relevance, evaluation of ecotoxicity, derivation of matrix-specific Tier 1 RBSLs (including soils) and determination of Tier 2 and 3 SSTLS. Chemicals are considered by class, aquatic (freshwater and saltwater) and terrestrial habitats are evaluated independently, and chemical concentrations are screened in all media of concern (air, soil, water, sediment). Data needs and decision points specific to ecological receptors are identified for each tier of the approach. Other aspects of the approach include consideration of contaminant migration pathways and habitats that are typical of Arctic conditions. Areas where ecological and human risk concerns may overlap are identified

Ecological risk assessment of hydropower dam construction based on ecological network analysis

OpenAIRE

Chen, Shaoqing; Fath, Brian D.; Chen, Bin

2010-01-01

Dam construction is regarded as one of the major factors contributing to significant modifications of the river ecosystems, and the ecological risk (ER) assessment of dam construction has received growing attention in recent years. In the present study, we explored the potential ecological risk caused by dam project based on the general principles of the ecological risk assessment. Ecological network analysis was proposed as the usable analytic method for the implement of ecological risk asse...

Ecological models and pesticide risk assessment: current modeling practice.

Science.gov (United States)

Schmolke, Amelie; Thorbek, Pernille; Chapman, Peter; Grimm, Volker

2010-04-01

Ecological risk assessments of pesticides usually focus on risk at the level of individuals, and are carried out by comparing exposure and toxicological endpoints. However, in most cases the protection goal is populations rather than individuals. On the population level, effects of pesticides depend not only on exposure and toxicity, but also on factors such as life history characteristics, population structure, timing of application, presence of refuges in time and space, and landscape structure. Ecological models can integrate such factors and have the potential to become important tools for the prediction of population-level effects of exposure to pesticides, thus allowing extrapolations, for example, from laboratory to field. Indeed, a broad range of ecological models have been applied to chemical risk assessment in the scientific literature, but so far such models have only rarely been used to support regulatory risk assessments of pesticides. To better understand the reasons for this situation, the current modeling practice in this field was assessed in the present study. The scientific literature was searched for relevant models and assessed according to nine characteristics: model type, model complexity, toxicity measure, exposure pattern, other factors, taxonomic group, risk assessment endpoint, parameterization, and model evaluation. The present study found that, although most models were of a high scientific standard, many of them would need modification before they are suitable for regulatory risk assessments. The main shortcomings of currently available models in the context of regulatory pesticide risk assessments were identified. When ecological models are applied to regulatory risk assessments, we recommend reviewing these models according to the nine characteristics evaluated here. (c) 2010 SETAC.

Use of ecological exposure units in ecological risk assessment

International Nuclear Information System (INIS)

Ferenbaugh, R.; Myers, O.; Gallegos, A.; Breshears, D.; Ebinger, M.

1995-01-01

The traditional approach to ecological risk assessment at hazardous waste sites that are being evaluated for cleanup under CERCLA or RCRA requirements is to focus on the immediate impacts at or adjacent to a site. While this may be acceptable in some situations, it is not ecologically defensible in situations where there are numerous contaminated sites in proximity to each other. In the latter case, transport from the sites, potential cumulative effects, and wide-ranging receptors must be considered. The concept of the Ecological Exposure Unit (EEU) has been proposed to address this situation. Ecological Exposure Units are defined on the basis of ecological considerations and each EEU may contain several to many contaminated sites. The initial steps involved in performing ecological risk assessments using the EEU approach include (1) selection of appropriate receptors and assessment endpoints, and (2) geographical definition of EEUs. At Los Alamos National Laboratory, receptors have been identified and EEUs have been defined for these receptors. GIS is being used as a tool to map EEUs. Receptors include representatives from threatened or endangered species, species reflecting status of ecological health, species with social or cultural relevance, and other species of concern. After definition of EEUs, cumulative impacts of all stressors at all sites within each EEU must be evaluated. The two major advantages to performing ecological risk assessments using this approach are that risk assessments are performed in a more scientifically defensible manner because they are performed on ecologically defined units and that resources are used optimally by minimizing redundant remedial activities

Enhancing the ecological risk assessment process.

Science.gov (United States)

Dale, Virginia H; Biddinger, Gregory R; Newman, Michael C; Oris, James T; Suter, Glenn W; Thompson, Timothy; Armitage, Thomas M; Meyer, Judith L; Allen-King, Richelle M; Burton, G Allen; Chapman, Peter M; Conquest, Loveday L; Fernandez, Ivan J; Landis, Wayne G; Master, Lawrence L; Mitsch, William J; Mueller, Thomas C; Rabeni, Charles F; Rodewald, Amanda D; Sanders, James G; van Heerden, Ivor L

2008-07-01

The Ecological Processes and Effects Committee of the US Environmental Protection Agency Science Advisory Board conducted a self-initiated study and convened a public workshop to characterize the state of the ecological risk assessment (ERA), with a view toward advancing the science and application of the process. That survey and analysis of ERA in decision making shows that such assessments have been most effective when clear management goals were included in the problem formulation; translated into information needs; and developed in collaboration with decision makers, assessors, scientists, and stakeholders. This process is best facilitated when risk managers, risk assessors, and stakeholders are engaged in an ongoing dialogue about problem formulation. Identification and acknowledgment of uncertainties that have the potential to profoundly affect the results and outcome of risk assessments also improves assessment effectiveness. Thus we suggest 1) through peer review of ERAs be conducted at the problem formulation stage and 2) the predictive power of risk-based decision making be expanded to reduce uncertainties through analytical and methodological approaches like life cycle analysis. Risk assessment and monitoring programs need better integration to reduce uncertainty and to evaluate risk management decision outcomes. Postdecision audit programs should be initiated to evaluate the environmental outcomes of risk-based decisions. In addition, a process should be developed to demonstrate how monitoring data can be used to reduce uncertainties. Ecological risk assessments should include the effects of chemical and nonchemical stressors at multiple levels of biological organization and spatial scale, and the extent and resolution of the pertinent scales and levels of organization should be explicitly considered during problem formulation. An approach to interpreting lines of evidence and weight of evidence is critically needed for complex assessments, and it would

Estimating cancer risks induced by CT screening for Korea population

International Nuclear Information System (INIS)

Yang, Hye Jeong; Yang, Won Seok

2016-01-01

Computed Tomography(CT) has been used to diagnose early stages of cancer and other diseases. Since the number of CT screening has been increasing, there is now a debate about the possible benefits and risks of CT screening on asymptomatic individuals. CT screening has definite benefits, however the radiation risk of screening an asymptomatic individual is a serious problem that cannot be overlooked. Despite its potential risks, CT screening for asymptomatic individual has been gradually increased in Korea and it is attributed to increase collective effective dose. Therefore, we reported the risk level of each organ which is included in scan field for CT screening and analyzed and then evaluated the risk level of Korean population comparison to others, Hong Kong, U.S. and U.K. populations. LARs are lower with older ages for all populations of both sexes. We recommend CT screening after the age of 40 because from that age, LAR decreases and the danger of top 5 cancer increases.

Ecological and health risk-based characterization of agricultural soils contaminated with polycyclic aromatic hydrocarbons in the vicinity of a chemical plant in China.

Science.gov (United States)

Liu, Geng; Niu, Junjie; Guo, Wenjiong; An, Xiangsheng; Zhao, Long

2016-11-01

Polycyclic aromatic hydrocarbons (PAHs) from chemical plants can cause serious pollution of surrounding agricultural soils. A comprehensive study of agricultural soils was conducted in the vicinity of a chemical plant in China to characterize the soil PAH concentration, as well as their composition and sources. Human health and a screening-level ecological risk assessment were conducted for PAH contamination in agricultural soils. The results showed that the total concentrations of 16 priority PAHs ranged from 250.49 to 9387.26 ng g(-1), with an average of 2780.42 ng g(-1). High molecular weight PAHs (four to six rings) were the dominant component, accounting for more than 60% of all PAHs. Principal component analysis (PCA) and positive matrix factorization model (PMF) suggested that diesel emissions, coal combustion, coke ovens, and fuel combustion and gasoline emissions were the main sources of PAHs in agricultural soils. The ecological risk assessment results based on the effects range-low (ERL), the effects range-median (ERM), and the ecological screening levels (ESL) indicated that the exposure to ∑PAH16 was >ERL, >ERM, and ≥ERL and ESL at 78.1% of the soil sampling stations, and could induce biological effects in mammals. The Bapeq concentrations posed a potential carcinogenic risk to humans. Further risk management and control of soil PAHs in these agricultural soils is required to ensure the safety of the biocoenosis and human health. Copyright © 2016 Elsevier Ltd. All rights reserved.

[Study on ecological risk assessment technology of fluoride pollution from arid oasis soil].

Science.gov (United States)

Xue, Su-Yin; Li, Ping; Wang, Sheng-Li; Nan, Zhong-Ren

2014-03-01

According to translocation regulation of fluoride in the typical oasis soil-plant system under field, an ecological risk assessment model of fluoride was established, and this model was used to assess ecological risk to fluoride pollution from suburban oasis soils in Baiyin City, which was specifically expressed with the potential ecological risk of bioavailability (ER(bc)) model to assess ecological risk of fluoride pollution in oasis regions. Results showed that the ecological risk indices of fluoride pollution from this region were 1.37-24.81, the level of risk at most sites was high to very high, the average ecological risk index was 11.28, belonged to very high risk. This indicated that in the suburb soil of Baiyin City needs to be concerned about the remediation of fluoride pollution.

D & D screening risk evaluation guidance

Energy Technology Data Exchange (ETDEWEB)

Robers, S.K.; Golden, K.M.; Wollert, D.A.

1995-09-01

The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D&D) facilities. Although this method has been developed for D&D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D&D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis.

Radiation risk from CT: implications for cancer screening.

Science.gov (United States)

Albert, Jeffrey M

2013-07-01

The cancer risks associated with patient exposure to radiation from medical imaging have become a major topic of debate. The higher doses necessary for technologies such as CT and the increasing utilization of these technologies further increase medical radiation exposure to the population. Furthermore, the use of CT for population-based cancer screening continues to be explored for common malignancies such as lung cancer and colorectal cancer. Given the known carcinogenic effects of ionizing radiation, this warrants evaluation of the balance between the benefit of early cancer detection and the risk of screening-induced malignancy. This report provides a brief review of the process of radiation carcino-genesis and the literature evaluating the risk of malignancy from CT, with a focus on the risks and benefits of CT for cancer screening. The available data suggest a small but real risk of radiation-induced malignancy from CT that could become significant at the population level with widespread use of CT-based screening. However, a growing body of literature suggests that the benefits of CT screening for lung cancer in high-risk patients and CT colonography for colorectal cancer may significantly outweigh the radiation risk. Future studies evaluating the benefits of CT screening should continue to consider potential radiation risks.

An electronic screen for triaging adolescent substance use by risk levels.

Science.gov (United States)

Levy, Sharon; Weiss, Roger; Sherritt, Lon; Ziemnik, Rosemary; Spalding, Allegra; Van Hook, Shari; Shrier, Lydia A

2014-09-01

Screening adolescents for substance use and intervening immediately can reduce the burden of addiction and substance-related morbidity. Several screening tools have been developed to identify problem substance use for adolescents, but none have been calibrated to triage adolescents into clinically relevant risk categories to guide interventions. To describe the psychometric properties of an electronic screen and brief assessment tool that triages adolescents into 4 actionable categories regarding their experience with nontobacco substance use. Adolescent patients (age range, 12-17 years) arriving for routine medical care at 2 outpatient primary care centers and 1 outpatient center for substance use treatment at a pediatric hospital completed an electronic screening tool from June 1, 2012, through March 31, 2013, that consisted of a question on the frequency of using 8 types of drugs in the past year (Screening to Brief Intervention). Additional questions assessed severity of any past-year substance use. Patients completed a structured diagnostic interview (Composite International Diagnostic Interview-Substance Abuse Module), yielding Diagnostic and Statistical Manual of Mental Disorders (Fifth Edition) substance use diagnoses. For the entire screen and the Screening to Brief Intervention, sensitivity and specificity for identifying nontobacco substance use, substance use disorders, severe substance use disorders, and tobacco dependence were calculated using the Composite International Diagnostic Interview-Substance Abuse Module as the criterion standard. Of 340 patients invited to participate, 216 (63.5%) enrolled in the study. Sensitivity and specificity were 100% and 84% (95% CI, 76%-89%) for identifying nontobacco substance use, 90% (95% CI, 77%-96%) and 94% (95% CI, 89%-96%) for substance use disorders, 100% and 94% (95% CI, 90%-96%) for severe substance use disorders, and 75% (95% CI, 52%-89%) and 98% (95% CI, 95%-100%) for nicotine dependence. No significant

Ecological concerns following Superstorm Sandy: stressor level and recreational activity levels affect perceptions of ecosystem.

Science.gov (United States)

Burger, Joanna

2015-06-01

Coastal habitats are vulnerable to storms, and with increasing urbanization, sea level rise, and storm frequency, some urban populations are at risk. This study examined perceptions of respondents in coastal and central New Jersey to Superstorm Sandy , including: 1) concerns about ecological resources and effects (open-ended question), 2) information sources for ecology of the coast (open-ended), and 3) ratings of a list of ecological services as a function of demographics, location (coastal, central Jersey), stressor level (power outages, high winds, flooding) and recreational rates. "Wildlife" and "fish" were the ecological concerns mentioned most often, while beaches and dunes were most often mentioned for environmental concerns. Television, radio, and web/internet were sources trusted for ecological information. The data indicate 1) stressor level was a better predictor of ratings of ecological services than geographical location, but days engaged in recreation contributed the most to variations in ratings, 2) ecological services were rated the highest by respondents with the highest stressor levels, and by those from the coast, compared to others, 3) Caucasians rated ecological services higher than all others, and 4) recreational rates were highest for coastal respondents, and ratings for ecological services increased with recreational rates. Only 20 % of respondents listed specific ecological services as one of their three most important environmental concerns. These data will be useful for increasing preparedness, enhancing educational strategies for shore protection, and providing managers and public policy makers with data essential to developing resiliency strategies.

Ecological risk assessment

National Research Council Canada - National Science Library

Suter, Glenn W; Barnthouse, L. W. (Lawrence W)

2007-01-01

Ecological risk assessment is commonly applied to the regulation of chemicals, the remediation of contaminated sites, the monitoring of importation of exotic organisms, the management of watersheds...

D ampersand D screening risk evaluation guidance

International Nuclear Information System (INIS)

Robers, S.K.; Golden, K.M.; Wollert, D.A.

1995-09-01

The Screening Risk Evaluation (SRE) guidance document is a set of guidelines provided for the uniform implementation of SREs performed on decontamination and decommissioning (D ampersand D) facilities. Although this method has been developed for D ampersand D facilities, it can be used for transition (EM-60) facilities as well. The SRE guidance produces screening risk scores reflecting levels of risk through the use of risk ranking indices. Five types of possible risk are calculated from the SRE: current releases, worker exposures, future releases, physical hazards, and criticality. The Current Release Index (CRI) calculates the current risk to human health and the environment, exterior to the building, from ongoing or probable releases within a one-year time period. The Worker Exposure Index (WEI) calculates the current risk to workers, occupants and visitors inside contaminated D ampersand D facilities due to contaminant exposure. The Future Release Index (FRI) calculates the hypothetical risk of future releases of contaminants, after one year, to human health and the environment. The Physical Hazards Index (PHI) calculates the risks to human health due to factors other than that of contaminants. Criticality is approached as a modifying factor to the entire SRE, due to the fact that criticality issues are strictly regulated under DOE. Screening risk results will be tabulated in matrix form, and Total Risk will be calculated (weighted equation) to produce a score on which to base early action recommendations. Other recommendations from the screening risk scores will be made based either on individual index scores or from reweighted Total Risk calculations. All recommendations based on the SRE will be made based on a combination of screening risk scores, decision drivers, and other considerations, as determined on a project-by-project basis

Combined ecological risks of nitrogen and phosphorus in European freshwaters

International Nuclear Information System (INIS)

Azevedo, Ligia B.; Zelm, Rosalie van; Leuven, Rob S.E.W.; Hendriks, A. Jan; Huijbregts, Mark A.J.

2015-01-01

Eutrophication is a key water quality issue triggered by increasing nitrogen (N) and phosphorus (P) levels and potentially posing risks to freshwater biota. We predicted the probability that an invertebrate species within a community assemblage becomes absent due to nutrient stress as the ecological risk (ER) for European lakes and streams subjected to N and P pollution from 1985 to 2011. The ER was calculated as a function of species-specific tolerances to NO 3 − and total P concentrations and water quality monitoring data. Lake and stream ER averaged 50% in the last monitored year (i.e. 2011) and we observed a decrease by 22% and 38% in lake and stream ER (respectively) of river basins since 1985. Additionally, the ER from N stress surpassed that of P in both freshwater systems. The ER can be applied to identify river basins most subjected to eutrophication risks and the main drivers of impacts. - Highlights: • Ecological risk was estimated as response additions of N and P. • The risk posed by N stress is higher than that by P in European freshwaters. • Ecological risks have remained unchanged in most European river basins. - Quantifying the ecological risk of invertebrate losses due to N and P pollution

Developing remediation criteria on the basis of health and ecological risks at a former sour gas plant site

International Nuclear Information System (INIS)

Brown, G. L.; Wilson, R. M.; Clyde, G. A.; Chollak, D. F.

1997-01-01

A human health and ecological risk assessment was completed for the Okotoks sour gas processing gas plant, based on the existing environmental sampling and toxicity testing that has been collected at the site since 1987. For the human health risk assessment, two potential scenarios were considered, including industrial use and parkland use. The ecological risk assessment involved synthesis of existing sampling and toxicity testing results as well as the assessment of potential risk to ecological receptors such as the meadow vole, red-tailed hawk and cattle. The assessment included chemical screening, receptor and exposure pathway selection, toxicity assessment of chemicals of concern, estimation of exposures, risk characterization and generation of soil and groundwater remediation criteria. Results of the assessments to date indicate that limited subsurface remediation is required for the protection of human health under industrial/parkland use. In contrast, ecological considerations will require remediation or reclamation of surface soil and the imposition of certain risk management controls, such as e. g. encumbrances on land title. 2 figs

Ecological interactions affecting population-level responses to chemical stress in Mesocyclops leuckarti.

Science.gov (United States)

Kulkarni, Devdutt; Hommen, Udo; Schäffer, Andreas; Preuss, Thomas G

2014-10-01

Higher tiers of ecological risk assessment (ERA) consider population and community-level endpoints. At the population level, the phenomenon of density dependence is one of the most important ecological processes that influence population dynamics. In this study, we investigated how different mechanisms of density dependence would influence population-level ERA of the cyclopoid copepod Mesocyclops leuckarti under toxicant exposure. We used a combined approach of laboratory experiments and individual-based modelling. An individual-based model was developed for M. leuckarti to simulate population dynamics under triphenyltin exposure based on individual-level ecological and toxicological data from laboratory experiments. The study primarily aimed to-(1) determine which life-cycle processes, based on feeding strategies, are most significant in determining density dependence (2) explore how these mechanisms of density dependence affect extrapolation from individual-level effects to the population level under toxicant exposure. Model simulations showed that cannibalism of nauplii that were already stressed by TPT exposure contributed to synergistic effects of biotic and abiotic factors and led to a twofold stress being exerted on the nauplii, thereby resulting in a higher population vulnerability compared to the scenario without cannibalism. Our results suggest that in population-level risk assessment, it is easy to underestimate toxicity unless underlying ecological interactions including mechanisms of population-level density regulation are considered. This study is an example of how a combined approach of experiments and mechanistic modelling can lead to a thorough understanding of ecological processes in ecotoxicology and enable a more realistic ERA. Copyright © 2014 Elsevier Ltd. All rights reserved.

Screening-level risk assessment for styrene-acrylonitrile (SAN) trimer detected in soil and groundwater.

Science.gov (United States)

Kirman, C R; Gargas, M L; Collins, J J; Rowlands, J C

2012-01-01

A screening-level risk assessment was conducted for styrene-acrylonitrile (SAN) Trimer detected at the Reich Farm Superfund site in Toms River, NJ. Consistent with a screening-level approach, on-site and off-site exposure scenarios were evaluated using assumptions that are expected to overestimate actual exposures and hazards at the site. Environmental sampling data collected for soil and groundwater were used to estimate exposure point concentrations. Several exposure scenarios were evaluated to assess potential on-site and off-site exposures, using parameter values for exposures to soil (oral, inhalation of particulates, and dermal contact) and groundwater (oral, dermal contact) to reflect central tendency exposure (CTE) and reasonable maximum exposure (RME) conditions. Three reference dose (RfD) values were derived for SAN Trimer for short-term, subchronic, and chronic exposures, based upon its effects on the liver in exposed rats. Benchmark (BMD) methods were used to assess the relationship between exposure and response, and to characterize appropriate points of departure (POD) for each RfD. An uncertainty factor of 300 was applied to each POD to yield RfD values of 0.1, 0.04, and 0.03 mg/kg-d for short-term, subchronic, and chronic exposures, respectively. Because a chronic cancer bioassay for SAN Trimer in rats (NTP 2011a) does not provide evidence of carcinogenicity, a cancer risk assessment is not appropriate for this chemical. Potential health hazards to human health were assessed using a hazard index (HI) approach, which considers the ratio of exposure dose (i.e., average daily dose, mg/kg-d) to toxicity dose (RfD, mg/kg-d) for each scenario. All CTE and RME HI values are well below 1 (where the average daily dose is equivalent to the RfD), indicating that there is no concern for potential noncancer effects in exposed populations even under the conservative assumptions of this screening-level assessment.

Screening-Level Risk Assessment for Styrene-Acrylonitrile (SAN) Trimer Detected in Soil and Groundwater

Science.gov (United States)

Kirman, C. R.; Gargas, M. L.; Collins, J. J.; Rowlands, J. C.

2012-01-01

A screening-level risk assessment was conducted for styrene-acrylonitrile (SAN) Trimer detected at the Reich Farm Superfund site in Toms River, NJ. Consistent with a screening-level approach, on-site and off-site exposure scenarios were evaluated using assumptions that are expected to overestimate actual exposures and hazards at the site. Environmental sampling data collected for soil and groundwater were used to estimate exposure point concentrations. Several exposure scenarios were evaluated to assess potential on-site and off-site exposures, using parameter values for exposures to soil (oral, inhalation of particulates, and dermal contact) and groundwater (oral, dermal contact) to reflect central tendency exposure (CTE) and reasonable maximum exposure (RME) conditions. Three reference dose (RfD) values were derived for SAN Trimer for short-term, subchronic, and chronic exposures, based upon its effects on the liver in exposed rats. Benchmark (BMD) methods were used to assess the relationship between exposure and response, and to characterize appropriate points of departure (POD) for each RfD. An uncertainty factor of 300 was applied to each POD to yield RfD values of 0.1, 0.04, and 0.03 mg/kg-d for short-term, subchronic, and chronic exposures, respectively. Because a chronic cancer bioassay for SAN Trimer in rats (NTP 2011a) does not provide evidence of carcinogenicity, a cancer risk assessment is not appropriate for this chemical. Potential health hazards to human health were assessed using a hazard index (HI) approach, which considers the ratio of exposure dose (i.e., average daily dose, mg/kg-d) to toxicity dose (RfD, mg/kg-d) for each scenario. All CTE and RME HI values are well below 1 (where the average daily dose is equivalent to the RfD), indicating that there is no concern for potential noncancer effects in exposed populations even under the conservative assumptions of this screening-level assessment. PMID:23030654

The sediments of the Venice Lagoon (Italy) evaluated in a screening risk assessment approach: part I--application of international sediment quality guidelines.

Science.gov (United States)

Apitz, Sabine E; Barbanti, Andrea; Bocci, Martina; Carlin, Anna; Montobbio, Laura; Bernstein, Alberto Giulio

2007-07-01

A number of studies carried out in recent years have shown the presence of a wide range of contaminants in the Venice Lagoon. It is important to have a good understanding of the ecological quality of Venice Lagoon sediments in order to 1) define and locate areas where a threat to the environment is present and therefore an intervention is needed (i.e., in situ assessment and management); and 2) define sustainable and environmentally correct ways of managing sediments that are to be dredged for navigational purposes or in relation to other interventions (i.e., ex situ management). This study reports on a critical comparison of chemical quality of sediments in Venice Lagoon and its subregions. Data on the Venice Lagoon were compiled from several studies conducted during the past decade on surface sediment contamination; temporal variation and risks for contaminants at depth were not addressed. The comparison of observed pollutant concentrations with local and internationally used sediment quality guidelines (SQGs) was used as a tool to benchmark different sites and for a tier I (screening) ecological risk assessment. Meaning and relevance of a number of SQGs are discussed, together with the options available for carrying out the comparison with sediment data. The screening of the Venice Lagoon sediment quality is discussed from a risk-assessment perspective and appropriate values for use in an in situ-ex situ management framework are suggested. Although there were some differences depending upon which specific SQGs were applied, different SQGs provided the same general picture of screening risk in Venice Lagoon: Although there are geographic differences, median levels for several contaminants in surface sediments exceeded a number of SQGs. Many contaminants exceed threshold effects SQGs, and Hg exceeds probable effects SQGs in most sub-basins except the southern Lagoon. Venice Lagoon south has the lowest screening risk levels, Venice Lagoon central/north has the

Demographic, social cognitive and social ecological predictors of intention and participation in screening for colorectal cancer

Directory of Open Access Journals (Sweden)

Duncan Amy

2011-01-01

Full Text Available Abstract Background Previous research points to differences between predictors of intention to screen for colorectal cancer (CRC and screening behavior, and suggests social ecological factors may influence screening behavior. The aim of this study was to compare the social cognitive and social ecological predictors of intention to screen with predictors of participation. Methods People aged 50 to 74 years recruited from the electoral roll completed a baseline survey (n = 376 and were subsequently invited to complete an immunochemical faecal occult blood test (iFOBT. Results Multivariate analyses revealed five predictors of intention to screen and two predictors of participation. Perceived barriers to CRC screening and perceived benefits of CRC screening were the only predictor of both outcomes. There was little support for social ecological factors, but measurement problems may have impacted this finding. Conclusions This study has confirmed that the predictors of intention to screen for CRC and screening behaviour, although overlapping, are not the same. Research should focus predominantly on those factors shown to predict participation. Perceptions about the barriers to screening and benefits of screening are key predictors of participation, and provide a focus for intervention programs.

PERSONAL VALUES, BELIEFS, AND ECOLOGICAL RISK PERCEPTION

Science.gov (United States)

A mail survey on ecological risk perception was administered in the summer of 2002 to a randomized sample of the lay public and to selected risk professionals at the U.S. Environmental Protection Agency (US EPA). The ranking of 24 ecological risk items, from global climate change...

[Uncertainty analysis of ecological risk assessment caused by heavy-metals deposition from MSWI emission].

Science.gov (United States)

Liao, Zhi-Heng; Sun, Jia-Ren; Wu, Dui; Fan, Shao-Jia; Ren, Ming-Zhong; Lü, Jia-Yang

2014-06-01

The CALPUFF model was applied to simulate the ground-level atmospheric concentrations of Pb and Cd from municipal solid waste incineration (MSWI) plants, and the soil concentration model was used to estimate soil concentration increments after atmospheric deposition based on Monte Carlo simulation, then ecological risk assessment was conducted by the potential ecological risk index method. The results showed that the largest atmospheric concentrations of Pb and Cd were 5.59 x 109-3) microg x m(-3) and 5.57 x 10(-4) microg x m(-3), respectively, while the maxima of soil concentration incremental medium of Pb and Cd were 2.26 mg x kg(-1) and 0.21 mg x kg(-1), respectively; High risk areas were located next to the incinerators, Cd contributed the most to the ecological risk, and Pb was basically free of pollution risk; Higher ecological hazard level was predicted at the most polluted point in urban areas with a 55.30% probability, while in rural areas, the most polluted point was assessed to moderate ecological hazard level with a 72.92% probability. In addition, sensitivity analysis of calculation parameters in the soil concentration model was conducted, which showed the simulated results of urban and rural area were most sensitive to soil mix depth and dry deposition rate, respectively.

A "weight of evidence" approach for the integration of environmental "triad" data to assess ecological risk and biological vulnerability.

Science.gov (United States)

Dagnino, Alessandro; Sforzini, Susanna; Dondero, Francesco; Fenoglio, Stefano; Bona, Elisa; Jensen, John; Viarengo, Aldo

2008-07-01

A new Expert Decision Support System (EDSS) that can integrate Triad data for assessing environmental risk and biological vulnerability at contaminated sites has been developed. Starting with ecosystem relevance, the EDSS assigns different weights to the results obtained from Triad disciplines. The following parameters have been employed: 1) chemical soil analyses (revealing the presence of potentially dangerous substances), 2) ecotoxicological bioassays (utilizing classical endpoints such as survival and reproduction rates), 3) biomarkers (showing sublethal pollutant effects), and 4) ecological parameters (assessing changes in community structure and functions). For each Triad discipline, the EDSS compares the data obtained at the studied field sites with reference values and calculates different 0-1 indexes (e.g., Chemical Risk Index, Ecotoxicological Risk Index, and Ecological Risk Index). The EDSS output consists of 3 indexes: 1) Environmental Risk index (EnvRI), quantifying the levels of biological damage at population-community level, 2) Biological Vulnerability Index (BVI), assessing the potential threats to biological equilibriums, and 3) Genotoxicity Index (GTI), screening genotoxicity effects. The EDSS has been applied in the integration of a battery of Triad data obtained during the European Union-funded Life Intervention in the Fraschetta Area (LINFA) project, which has been carried out in order to estimate the potential risk from soils of a highly anthropized area (Alessandria, Italy) mainly impacted by deposition of atmospheric pollutants. Results obtained during 4 seasonal sampling campaigns (2004-2005) show maximum values of EnvRI in sites A and B (characterized by industrial releases) and lower levels in site D (affected by vehicular traffic emissions). All 3 potentially polluted sites have shown high levels of BVI and GTI, suggesting a general change from reference conditions (site C).

Preclinical screening for retinopathy of prematurity risk using IGF1 levels at 3 weeks post-partum.

Science.gov (United States)

Pérez-Muñuzuri, Alejandro; Couce-Pico, Maria Luz; Baña-Souto, Ana; López-Suárez, Olalla; Iglesias-Deus, Alicia; Blanco-Teijeiro, José; Fernández-Lorenzo, José Ramón; Fraga-Bermúdez, José María

2014-01-01

Following current recommendations for preventing retinopathy of prematurity (ROP) involves screening a large number of patients. We performed a prospective study to establish a useful screening system for ROP prediction and we have determined that measuring serum levels of IGF1 at week three and the presence of sepsis have a high predictive value for the subsequent development of ROP. A total of 145 premature newborn, with birthweight <1500 g and/or <32 weeks gestational age, were enrolled. 26.9% of them showed some form of retinopathy. A significant association was found between the development of retinopathy and each of the following variables: early gestational age, low birthweight, requiring mechanical ventilation, oxygen treatment, intracranial haemorrhage, sepsis during the first three weeks, bronchopulmonary dysplasia, the need for erythrocyte transfusion, erythropoietin treatment, and low levels of serum IGF1 in the third week. A multiple logistic regression analysis was used to obtain curves for the probability of developing ROP, based on the main factors linked with ROP, namely serum levels of IGF1 and presence of sepsis. Such preclinical screening has the ability to identify patients with high-risk of developing retinopathy and should lead to better prediction for ROP, while at the same time optimising the use of clinical resources, both human and material.

Preparticipation Screening of Athletic Officials: SEC Football Referees at Risk.

Science.gov (United States)

Turner, John L; Walters, Rod; Leski, Mark J; Saywell, Robert M; Wooldridge, J Scott

2003-03-01

Although preparticipation screening for athletes is commonplace, few studies have addressed the issue for those officiating at games. To review current data on physiologic stress on sports officials, to obtain prevalence data on health parameters for football officials, and to determine the outcomes when screening criteria are applied in preseason exams. A protocol was established using health history questionnaires and physical exams with laboratory screening to assess the health of all football officials working in the Southeastern Conference (SEC) from 1997 to 2000. The main outcome measure was the prevalence of cardiac risk factors as determined by American College of Sports Medicine guidelines. Initial screening of 102 football officials revealed that 10.1% of SEC referees had elevated systolic blood pressure, 13.9% had elevated diastolic blood pressure, and 3.8% had resting tachycardia. Average body mass index (BMI) was 28.6 kg/m2, with 87.3% having a BMI that exceeded 25 (overweight). About one-third (31.6%) had a BMI greater than 30 (obese). Total fasting cholesterol exceeded 200 mg/dL in 44.2%, HDL levels were below 35 mg/dL in 34.3%, and LDL levels were above 120 mg/dL in 62.3%. Compared with age-adjusted national data, there were more overweight and more obese officials, but they had lower systolic and diastolic blood pressures and lower mean total cholesterol levels. Using the Framingham Study prediction model to estimate coronary heart disease (CHD) risk, analysis revealed that referees had a lower risk than the national 10-year CHD risk but a higher risk compared with that of the low-risk population. These data reveal a greater need for graded exercise testing. The higher rates of obesity among officials will promote further screening for CHD risk factors.

Risks of Endometrial Cancer Screening

Science.gov (United States)

... Health history and certain medicines can affect the risk of developing endometrial cancer. Anything that increases your ... have abnormal vaginal bleeding, check with your doctor. Risks of Endometrial Cancer Screening Key Points Screening tests ...

Risks of Esophageal Cancer Screening

Science.gov (United States)

... alcohol use, and Barrett esophagus can affect the risk of developing esophageal cancer. Anything that increases the ... tissue gives off less light than normal tissue. Risks of Esophageal Cancer Screening Key Points Screening tests ...

Risks of Cervical Cancer Screening

Science.gov (United States)

... women. Human papillomavirus (HPV) infection is the major risk factor for cervical cancer. Although most women with ... clinical trials is available from the NCI website . Risks of Cervical Cancer Screening Key Points Screening tests ...

[Heavy metal pollution characteristics and ecological risk analysis for soil in Phyllostachys praecox stands of Lin'an].

Science.gov (United States)

Fang, Xiao-bo; Shi, Han; Liao, Xin-feng; Lou, Zhong; Zhou, Lyu-yan; Yu, Hai-xia; Yao, Lin; Sun, Li-ping

2015-06-01

An investigation was carried out in an attempt to reveal the characteristics of heavy metals contamination in the soils of Phyllostachys praecox forest in Lin' an. Based on the concentrations of Hg, As, Cu, Pb, Zn, Cd, Cr, Ni, Co and Mn in 160 topsoil samples, the pollution status and ecological risks of heavy metals in the soils were assessed by single factor pollution index, Nemerow integrated pollution index and Hankanson potential ecological risk index. The spatial variability of heavy metal concentrations in the soils closely related to the distribution of traffic, industrial and livestock pollution sources. The average concentrations of Hg, As, Cu, Pb, Zn, Cd, Cr, Ni, Co and Mn in the soils were 0.16, 7.41, 34.36, 87.98, 103.98, 0.26, 59.12, 29.56, 11.44 and 350.26 mg · kg(-1), respectively. Pb, Cd, Zn and Cu concentrations were as 2.89, 1.70, 1.12 and 1.12 times as the background values of soil in Zhejiang Province, respectively. But their concentrations were all lower than the threshold values of the National Environmental Quality Standard for Soil (GB 15618-1995). The average single factor pollution index revealed that the level of heavy metal pollution in the soils was in order of Pb>Cd>Cu= Zn>Hg>As>Ni>Co>Cr>Mn. Pb pollution was of moderate level while Cd, Cu and Zn pollutions were slight. There was no soil pollution caused by the other heavy metals. However, the Nemerow integrated pollution index showed that all the 160 soil samples were contaminated by heavy metals to a certain extent. Among total 160 soil samples, slight pollution level, moderate pollution level and heavy pollution level accounted for 55.6%, 29.4% and 15.0%, respectively. The average single factor potential ecological risk index (Er(i)) implied that the potential ecological risk related to Cd reached moderate level, while the others were of slight level. Furthermore, Cd and Hg showed higher potential ecological risk indices which reached up to 256.82 and 187.33 respectively

US EPA's Ecological Risk Assessment Support Center ...

Science.gov (United States)

BackgroundThe ERASC provides technical information and addresses scientific questions of concern or interest on topics relevant to ecological risk assessment at hazardous waste sites for EPA's Office of Solid Waste and Emergency Response (OSWER) personnel and the Office of Resource Conservation and Recovery (ORCR) staff. Requests are channeled to ERASC through the Ecological Risk Assessment Forum (ERAF). To assess emerging and complex scientific issues that require expert judgment, the ERASC relies on the expertise of scientists and engineers located throughout EPA's Office of Research and Development (ORD) labs and centers.ResponseERASC develops responses that reflect the state of the science for ecological risk assessment and also provides a communication point for the distribution of the responses to other interested parties. For further information, contact Ecology_ERASC@epa.gov or call 513-569-7940.

Preclinical screening for retinopathy of prematurity risk using IGF1 levels at 3 weeks post-partum.

Directory of Open Access Journals (Sweden)

Alejandro Pérez-Muñuzuri

Full Text Available Following current recommendations for preventing retinopathy of prematurity (ROP involves screening a large number of patients. We performed a prospective study to establish a useful screening system for ROP prediction and we have determined that measuring serum levels of IGF1 at week three and the presence of sepsis have a high predictive value for the subsequent development of ROP. A total of 145 premature newborn, with birthweight <1500 g and/or <32 weeks gestational age, were enrolled. 26.9% of them showed some form of retinopathy. A significant association was found between the development of retinopathy and each of the following variables: early gestational age, low birthweight, requiring mechanical ventilation, oxygen treatment, intracranial haemorrhage, sepsis during the first three weeks, bronchopulmonary dysplasia, the need for erythrocyte transfusion, erythropoietin treatment, and low levels of serum IGF1 in the third week. A multiple logistic regression analysis was used to obtain curves for the probability of developing ROP, based on the main factors linked with ROP, namely serum levels of IGF1 and presence of sepsis. Such preclinical screening has the ability to identify patients with high-risk of developing retinopathy and should lead to better prediction for ROP, while at the same time optimising the use of clinical resources, both human and material.

A refined ecological risk assessment for California red-legged frog, Delta smelt, and California tiger salamander exposed to malathion.

Science.gov (United States)

Clemow, Yvonne H; Manning, Gillian E; Breton, Roger L; Winchell, Michael F; Padilla, Lauren; Rodney, Sara I; Hanzas, John P; Estes, Tammara L; Budreski, Katherine; Toth, Brent N; Hill, Katie L; Priest, Colleen D; Teed, R Scott; Knopper, Loren D; Moore, Dwayne Rj; Stone, Christopher T; Whatling, Paul

2018-03-01

The California red-legged frog (CRLF), Delta smelt (DS), and California tiger salamander (CTS) are 3 species listed under the United States Federal Endangered Species Act (ESA), all of which inhabit aquatic ecosystems in California. The US Environmental Protection Agency (USEPA) has conducted deterministic screening-level risk assessments for these species potentially exposed to malathion, an organophosphorus insecticide and acaricide. Results from our screening-level analyses identified potential risk of direct effects to DS as well as indirect effects to all 3 species via reduction in prey. Accordingly, for those species and scenarios in which risk was identified at the screening level, we conducted a refined probabilistic risk assessment for CRLF, DS, and CTS. The refined ecological risk assessment (ERA) was conducted using best available data and approaches, as recommended by the 2013 National Research Council (NRC) report "Assessing Risks to Endangered and Threatened Species from Pesticides." Refined aquatic exposure models including the Pesticide Root Zone Model (PRZM), the Vegetative Filter Strip Modeling System (VFSMOD), the Variable Volume Water Model (VVWM), the Exposure Analysis Modeling System (EXAMS), and the Soil and Water Assessment Tool (SWAT) were used to generate estimated exposure concentrations (EECs) for malathion based on worst-case scenarios in California. Refined effects analyses involved developing concentration-response curves for fish and species sensitivity distributions (SSDs) for fish and aquatic invertebrates. Quantitative risk curves, field and mesocosm studies, surface-water monitoring data, and incident reports were considered in a weight-of-evidence approach. Currently, labeled uses of malathion are not expected to result in direct effects to CRLF, DS or CTS, or indirect effects due to effects on fish and invertebrate prey. Integr Environ Assess Manag 2018;14:224-239. © 2017 The Authors. Integrated Environmental Assessment and

[Scale effect of Li-Xiang Railway construction impact on landscape pattern and its ecological risk].

Science.gov (United States)

Wang, De-zhi; Qiu, Peng-hua; Fang, Yuan-min

2015-08-01

As a large corridor project, plateau railway has multiple points and passes various sensitive environments along the railway. The determination of the scope of impact on ecological environment from railway construction is often controversial in ecological impact assessment work. Taking the Tangbu-Jiantang section of Li-Xiang Railway as study object, and using present land use map (1:10000) in 2012 and DEM as data sources, corridor cutting degree index ( CCI) and cumulative effect index of corridor (CCEI) were established by topology, buffer zone and landscape metrics methods. Besides, the ecological risk index used for railway construction was improved. By quantitative analysis of characteristics of the spatio-temporal change of landscape pattern and its evolution style at different spatial scales before and after railway construction, the most appropriate evaluation scale of the railway was obtained. Then the characteristics of the spatio-temporal variation of ecological risk within this scale before and after railway construction were analyzed. The results indicated that the cutting model and degree of railway corridor to various landscape types could be effectively reflected by CCI, and the exposure and harm relations between risk sources and risk receptors of railway can be measured by CCEI. After the railway construction, the railway corridor would cause a great deal of middle cutting effect on the landscape along the railroad, which would influence wood land and grassland landscape most greatly, while would cause less effect of edge cutting and internal cutting. Landscape indices within the 600 m buffer zone demonstrated the most obvious scale effect, therefore, the 600 m zone of the railway was set as the most suitable range of ecological impact assessment. Before railway construction, the low ecological risk level covered the biggest part of the 600 m assessment zone. However, after the railway construction, the ecological risk increased significantly, and

Assessment of radiation risk as a part of ecological risk in the Republic of Belarus after the Chernobyl accident

International Nuclear Information System (INIS)

Saltanova, Irina; Saltanov, Eugene

2008-01-01

Full text: The purpose of the work: foundation for principles of planning protection measures, that provide safety for population activity on the territories, contaminated with radio-nuclides, by analysing radio-chemical situation, using risk assessment methods. Problems set in the work: -) Analyses of radiation risk in the structure of ecological risk in the territory of the Republic of Belarus after the Chernobyl accident; -) Investigation of chemical risk level, connected with air pollution from stationary objects exhausts, for the territories, contaminated with Chernobyl radio-nuclides; -) Modelling of the combined impact of ionising radiation and chemical carcinogen for the possible ecological risk assessment; -) Involving modern geo informational systems in the radio-ecological risk assessment process; -) Foundation for the assessment methodology of the complex influence of negative factors in the territories, contaminated with Chernobyl radio-nuclides. The problems are solved by carrying out specific experiments and by analysing published and own data on radioactive and chemical contamination of some regions of Belarus. Major findings: Radiation input to the really registered carcinogens is estimated to app. 10 %. In case of multiple factors influence of different contaminators of industrial and natural origin (i.e. radiation is not the only negative factor), ignorance of non-radiation origin factors may seriously distort estimation of radiation risk, when it is related to the registered effects. Radiation should be in no way treated as the major factor of real ecological risk in Belarus. Method for comparative analysis of territories' ecological risk level is developed and implemented. A GIS segment, that includes subsystem of the real and forecasted radio-ecological mapping, is created. The authors grounded the experimental model for study the complex influence of radioactive and non-radioactive (chemical carcinogen) factors. Revealed dependencies 'dose

A survey of ecological risk assessment at DOE facilities

International Nuclear Information System (INIS)

Barnthouse, L.W.; Bascietto, J.; Joseph, T.; Bilyard, G.

1992-01-01

The US Department of Energy (DOE) Risk-Based Standards Working Group is studying standard-setting and remedial action based on realistic estimates of human health and ecological risks. Federal and state regulations require DOE to assess ecological risks due to present and past operation of DOE facilities and ecological damage caused by remedial actions. Unfortunately, little technical guidance has been provided by regulatory agencies about how these assessments should be performed or what constitutes an adequate assessment. Active ecological research, environmental characterization, and ecological risk assessment programs are already underway at many locations. Some of these programs were established more than 30 years ago. Because of the strength of its existing programs and the depth of expertise available within the DOE complex, the agency is in a position to lead in developing ecological risk assessment procedures that are fully consistent with the general principles defined by EPA and that will ensure environmentally sound and cost-effective restoration of its sites. As a prelude to guidance development, the working group conducted a survey of ecological risk assessment activities at a subset of major DOE facilities. The survey was intended to (1) identify approaches now being used in ecological risk assessments performed by DOE staff and contractors at each site, (2) record successes and failures of these approaches, (3) identify new technical developments with potential for general application to many DOE facilities, and (4) identify major data needs, data resources, and methodological deficiencies

Regional Ecological Risk Assessment in the Huai River Watershed during 2010–2015

Directory of Open Access Journals (Sweden)

Yan Lu

2017-12-01

Full Text Available Ecosystem deterioration has been and is still a serious threat to human survival and regional economic development. Theoretical and methodological challenges exist in assessing ecological risk of watershed ecosystem that is imposed by natural changes or human activities. To fill this research gap, this research proposes an interdisciplinary and quantitative methodology based on some techniques such as the Procedure for Ecological Tiered Assessment of Risk (PETAR, the Entropy, and the Celluar Automata Markov (CA-Markov. We focused on six vulnerable environmental variables, namely land-use change, water quantity, water quality, gross domestic product (GDP, environmental pollutants, and soil erosion in the Huai River watershed in the Henan Province in order to build multi-dimensional quantitative method. Further, the Coupling Coordination Degree Model is constructed, and the “threshold index” is also addressed to reflect the limitation of ecological risk. Our results show that the spatio-temperal distribution of the eco-environmental quality has greatly varied across this study area during different time spans. Natural eco-environmental quality has moderately degraded in 70% of this study area (mainly agricultural region, at a prefectural level from 2000 to 2010, and has slightly improved over the agricultural region (<170 m above sea level during 2010–2015. However, when considering negative stressors from human social system on the natural ecosystem, the extent and distribution of the ecological risk varied across the whole area during 2000–2015. The results show that there was almost 90.40% of this region under the ecological risk, with varying extents over the study time, e.g., Kaifeng, Shangqiu, Xuchang, and Xinyang, with a moderate deterioration in the eco-environmental quality, and Zhengzhou with a slight deterioration in the eco-environmental quality. This paper provides a valuable perspective for governments at all levels to manage

Soil-ecological risks for soil degradation estimation

Science.gov (United States)

Trifonova, Tatiana; Shirkin, Leonid; Kust, German; Andreeva, Olga

2016-04-01

Soil degradation includes the processes of soil properties and quality worsening, primarily from the point of view of their productivity and decrease of ecosystem services quality. Complete soil cover destruction and/or functioning termination of soil forms of organic life are considered as extreme stages of soil degradation, and for the fragile ecosystems they are normally considered in the network of their desertification, land degradation and droughts /DLDD/ concept. Block-model of ecotoxic effects, generating soil and ecosystem degradation, has been developed as a result of the long-term field and laboratory research of sod-podzol soils, contaminated with waste, containing heavy metals. The model highlights soil degradation mechanisms, caused by direct and indirect impact of ecotoxicants on "phytocenosis- soil" system and their combination, frequently causing synergistic effect. The sequence of occurring changes here can be formalized as a theory of change (succession of interrelated events). Several stages are distinguished here - from heavy metals leaching (releasing) in waste and their migration downward the soil profile to phytoproductivity decrease and certain phytocenosis composition changes. Phytoproductivity decrease leads to the reduction of cellulose content introduced into the soil. The described feedback mechanism acts as a factor of sod-podzolic soil self-purification and stability. It has been shown, that using phytomass productivity index, integrally reflecting the worsening of soil properties complex, it is possible to solve the problems dealing with the dose-reflecting reactions creation and determination of critical levels of load for phytocenosis and corresponding soil-ecological risks. Soil-ecological risk in "phytocenosis- soil" system means probable negative changes and the loss of some ecosystem functions during the transformation process of dead organic substance energy for the new biomass composition. Soil-ecological risks estimation is

Heavy metal pollution and ecological risk assessment of the paddy soils near a zinc-lead mining area in Hunan.

Science.gov (United States)

Lu, Sijin; Wang, Yeyao; Teng, Yanguo; Yu, Xuan

2015-10-01

Soil pollution by Cd, Hg, As, Pb, Cr, Cu, and Zn was characterized in the area of the mining and smelting of metal ores at Guiyang, northeast of Hunan Province. A total of 150 topsoil (0-20 cm) samples were collected in May 2012 with a nominal density of one sample per 4 km(2). High concentrations of heavy metals especially, Cd, Zn, and Pb were found in many of the samples taken from surrounding paddy soil, indicating a certain extent of spreading of heavy metal pollution. Sequential extraction technique and risk assessment code (RAC) were used to study the mobility of chemical forms of heavy metals in the soils and their ecological risk. The results reveal that Cd represents a high ecological risk due to its highest percentage of the exchangeable and carbonate fractions. The metals of Zn and Cu pose a medium risk, and the rest of the metals represent a low environmental risk. The range of the potential ecological risk of soil calculated by risk index (RI) was 123.5~2791.2 and revealed a considerable-high ecological risk in study area especially in the neighboring and surrounding the mining activities area. Additionally, cluster analyses suggested that metals such as Pb, As, Hg, Zn, and Cd could be from the same sources probably related to the acidic drainage and wind transport of dust. Cluster analysis also clearly distinguishes the samples with similar characteristics according to their spatial distribution. The results could be used during the ecological risk screening stage, in conjunction with total concentrations and metal fractionation values to better estimate ecological risk.

Ecological Risk Assessment of Genetically Modified Higher Plants (GMHP)

DEFF Research Database (Denmark)

Kjær, C.; Damgaard, C.; Kjellsson, G.

Preface This publication is a first version of a manual identifying the data needs for ecological risk assessment of genetically modified higher plants (GMHP). It is the intention of the authors to stimulate further discussion of what data are needed in order to conduct a proper ecological risk...... of the project Biotechnology: elements in environmental risk assessment of genetically modified plants. December 1999 Christian Kjær Introduction In ecological risk assessment of transgenic plants, information on a wide range of subjects is needed for an effective and reliable assessment procedure...... in the amendment to the directive. This report suggests a structured way to identify the type of data needed to perform a sound ecological risk assessment for genetically modified higher plants (GMHP). The identified data types are intended to support the evaluation of the following risks: risk of invasion...

Estimating radiation risk induced by CT screening for Korean population

Science.gov (United States)

Yang, Won Seok; Yang, Hye Jeong; Min, Byung In

2017-02-01

The purposes of this study are to estimate the radiation risks induced by chest/abdomen computed tomography (CT) screening for healthcare and to determine the cancer risk level of the Korean population compared to other populations. We used an ImPACT CT Patient Dosimetry Calculator to compute the organ effective dose induced by CT screening (chest, low-dose chest, abdomen/pelvis, and chest/abdomen/pelvis CT). A risk model was applied using principles based on the BEIR VII Report in order to estimate the lifetime attributable risk (LAR) using the Korean Life Table 2010. In addition, several countries including Hong Kong, the United States (U.S.), and the United Kingdom, were selected for comparison. Herein, each population exposed radiation dose of 100 mSv was classified according to country, gender and age. For each CT screening the total organ effective dose calculated by ImPACT was 6.2, 1.5, 5.2 and 11.4 mSv, respectively. In the case of Korean female LAR, it was similar to Hong Kong female but lower than those of U.S. and U.K. females, except for those in their twenties. The LAR of Korean males was the highest for all types of CT screening. However, the difference of the risk level was negligible because of the quite low value.

Microplastics: addressing ecological risk through lessons learned.

Science.gov (United States)

Syberg, Kristian; Khan, Farhan R; Selck, Henriette; Palmqvist, Annemette; Banta, Gary T; Daley, Jennifer; Sano, Larissa; Duhaime, Melissa B

2015-05-01

Plastic litter is an environmental problem of great concern. Despite the magnitude of the plastic pollution in our water bodies, only limited scientific understanding is available about the risk to the environment, particularly for microplastics. The apparent magnitude of the problem calls for quickly developing sound scientific guidance on the ecological risks of microplastics. The authors suggest that future research into microplastics risks should be guided by lessons learned from the more advanced and better understood areas of (eco) toxicology of engineered nanoparticles and mixture toxicity. Relevant examples of advances in these two fields are provided to help accelerate the scientific learning curve within the relatively unexplored area of microplastics risk assessment. Finally, the authors advocate an expansion of the "vector effect" hypothesis with regard to microplastics risk to help focus research of microplastics environmental risk at different levels of biological and environmental organization. © 2015 SETAC.

Evaluation of a multiple ecological level child obesity prevention program: Switch® what you Do, View, and Chew

Directory of Open Access Journals (Sweden)

Callahan Randi

2009-09-01

Full Text Available Abstract Background Schools are the most frequent target for intervention programs aimed at preventing child obesity; however, the overall effectiveness of these programs has been limited. It has therefore been recommended that interventions target multiple ecological levels (community, family, school and individual to have greater success in changing risk behaviors for obesity. This study examined the immediate and short-term, sustained effects of the Switch program, which targeted three behaviors (decreasing children's screen time, increasing fruit and vegetable consumption, and increasing physical activity at three ecological levels (the family, school, and community. Methods Participants were 1,323 children and their parents from 10 schools in two states. Schools were matched and randomly assigned to treatment and control. Measures of the key behaviors and body mass index were collected at baseline, immediately post-intervention, and 6 months post-intervention. Results The effect sizes of the differences between treatment and control groups ranged between small (Cohen's d = 0.15 for body mass index at 6 months post-intervention to large (1.38; parent report of screen time at 6 months post-intervention, controlling for baseline levels. There was a significant difference in parent-reported screen time at post-intervention in the experimental group, and this effect was maintained at 6 months post-intervention (a difference of about 2 hours/week. The experimental group also showed a significant increase in parent-reported fruit and vegetable consumption while child-reported fruit and vegetable consumption was marginally significant. At the 6-month follow-up, parent-reported screen time was significantly lower, and parent and child-reported fruit and vegetable consumption was significantly increased. There were no significant effects on pedometer measures of physical activity or body mass index in the experimental group. The intervention effects

The assessment of sediment screening risk in Venice Lagoon and other coastal areas using international sediment quality guidelines

International Nuclear Information System (INIS)

Apitz, S.A.; Barbanti, A.; Bocci, M.; Delaney, E.; Bernstein, A.G.; Montobbio, L.

2007-01-01

A number of studies carried out in recent years have shown the presence of a wide range of contaminants in the Venice Lagoon. It is important to have a good understanding of the ecological quality of Venice Lagoon sediments, in order to: i) define and locate areas where a threat to the environment is present and therefore an intervention is needed (i.e. in situ assessment and management); and ii) define sustainable and environmentally correct ways of managing sediments which are to be dredged for navigational purposes or in relation to other interventions (i.e., ex situ management). Materials and Methods: To examine how various regional and international SQGs 'classed' screening risk in Venice Lagoon sediments, data on median contaminant levels in surface sediments in Venice Lagoon resulting from a literature review were compared to a range of local and international sediment quality guidelines (SQGs). Then data on sediment contaminant levels in various areas and sub-basins of Venice Lagoon (main Lagoon, Porto Marghera and Venice City Canals) and in other regional and international transitional and coastal ecosystems with various levels of human impact (urbanization and industrialization) were evaluated based upon a selected consensus-based SQG. Finally, screening sediment quality for all of Venice Lagoon was mapped and contoured, relative to this consensus-based SQG and briefly compared with direct toxicity measurement through a battery of bioassays. Results: SQGs allow the sediment areas to be put in terms of potential, or screening, risk. Although there were some differences depending upon which specific SQGs were applied, the Venice SQGs and other international SQGs provided the same general picture of screening risk in Venice Lagoon despite geographic differences. Venice Lagoon South has the lowest screening risk levels, Venice Lagoon Central/North has the highest (and is nearest to the Porto Marghera and Venice City Canals sites). Discussion: The Venice

A tiered approach for probabilistic ecological risk assessment of contaminated sites

International Nuclear Information System (INIS)

Zolezzi, M.; Nicolella, C.; Tarazona, J.V.

2005-01-01

This paper presents a tiered methodology for probabilistic ecological risk assessment. The proposed approach starts from deterministic comparison (ratio) of single exposure concentration and threshold or safe level calculated from a dose-response relationship, goes through comparison of probabilistic distributions that describe exposure values and toxicological responses of organisms to the chemical of concern, and finally determines the so called distribution-based quotients (DBQs). In order to illustrate the proposed approach, soil concentrations of 1,2,4-trichlorobenzene (1,2,4- TCB) measured in an industrial contaminated site were used for site-specific probabilistic ecological risks assessment. By using probabilistic distributions, the risk, which exceeds a level of concern for soil organisms with the deterministic approach, is associated to the presence of hot spots reaching concentrations able to affect acutely more than 50% of the soil species, while the large majority of the area presents 1,2,4- TCB concentrations below those reported as toxic [it

[Ecological risks of reclaimed water irrigation: a review].

Science.gov (United States)

Chen, Wei-Ping; Zhang, Wei-Ling; Pan, Neng; Jiao, Wen-Tao

2012-12-01

Wastewater reclamation and reuse have become an important approach to alleviate the water crisis in China because of its social, economic and ecological benefits. The irrigation on urban green space and farmland is the primary utilization of reclaimed water, which has been practiced world widely. To understand the risk of reclaimed water irrigation, we summarized and reviewed the publications associated with typical pollutants in reclaimed water including salts, nitrogen, heavy metals, emerging pollutants and pathogens, systematically analyzed the ecological risk posed by reclaimed water irrigation regarding plant growth, groundwater quality and public health. Studies showed that salt and salt ions were the major risk sources of reclaimed water irrigation, spreading disease was another potential risk of using reclaimed water, and emerging pollutants was the hot topic in researches of ecological risk. Based on overseas experiences, risk control measures on reclaimed water irrigation in urban green space and farmland were proposed. Five recommendations were given to promote the safe use of reclaimed water irrigation including (1) strengthen long-term in situ monitoring, (2) promote the modeling studies, (3) build up the connections of reclaimed water quality, irrigation management and ecological risk, (4) evaluate the soil bearing capacity of reclaimed water irrigation, (5) and establish risk management system of reclaimed water reuse.

Health and ecological risk-based characterization of soil and sediment contamination in shipyard with long-term use of DDT-containing antifouling paint

Energy Technology Data Exchange (ETDEWEB)

Guo, Guanlin; Zhang, Chao [State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); Wu, Guanglong; Ding, Qiong [Foreign Economic Cooperation Office, Ministry of Environmental Protection of China, Beijing, 100035 (China); Wang, Shijie [State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012 (China); Li, Fasheng, E-mail: Lifs@craes.org.cn [State Key Laboratory of Environmental Criteria and Risk Assessment, Chinese Research Academy of Environmental Sciences, Beijing 100012 (China)

2013-04-15

Dichlorodiphenyltrichloroethane (DDT) was a frequently occurring type of persistent organic environmental pollutant in China and DDT-containing antifouling paint could be the main contributor of DDT to shipyards and fishing harbors. A field survey was conducted in a shipyard in southern China to investigate the content and distribution of DDT in soil and sediments. Human health and screening-level ecological risk assessments were conducted for DDT contamination in soil and sediments and the results indicated that total DDT in all samples tested exceeded present advisory safe limits. Analysis of the composition and distribution implicated DDT-containing antifouling paint used for ship maintenance as an important source of DDT. Individual and cumulative health risks for residents exceeded the extra lifetime cancer risks of 10{sup −6} and 10{sup −5}, mainly from exposure to soil, ingestion and dermal contact. DDT in sediments is associated with a high level of toxicity for the benthic community when > 99% of samples exceed the threshold concentration likely to be responsible for effects and severe effects. Further risk control for DDT is required to ensure safety for human health, the benthic community and the environment. - Highlights: ► DDT ranked high concentration both in sediments and soil in a shipyard. ► Composition analysis indicated DDT antifouling paint was the main source. ► High loading DDT in sediments resulted in high probability of ecological risks. ► Potential health risks for residents were mainly from the exposure of ingestion.

Health and ecological risk-based characterization of soil and sediment contamination in shipyard with long-term use of DDT-containing antifouling paint

International Nuclear Information System (INIS)

Guo, Guanlin; Zhang, Chao; Wu, Guanglong; Ding, Qiong; Wang, Shijie; Li, Fasheng

2013-01-01

Dichlorodiphenyltrichloroethane (DDT) was a frequently occurring type of persistent organic environmental pollutant in China and DDT-containing antifouling paint could be the main contributor of DDT to shipyards and fishing harbors. A field survey was conducted in a shipyard in southern China to investigate the content and distribution of DDT in soil and sediments. Human health and screening-level ecological risk assessments were conducted for DDT contamination in soil and sediments and the results indicated that total DDT in all samples tested exceeded present advisory safe limits. Analysis of the composition and distribution implicated DDT-containing antifouling paint used for ship maintenance as an important source of DDT. Individual and cumulative health risks for residents exceeded the extra lifetime cancer risks of 10 −6 and 10 −5 , mainly from exposure to soil, ingestion and dermal contact. DDT in sediments is associated with a high level of toxicity for the benthic community when > 99% of samples exceed the threshold concentration likely to be responsible for effects and severe effects. Further risk control for DDT is required to ensure safety for human health, the benthic community and the environment. - Highlights: ► DDT ranked high concentration both in sediments and soil in a shipyard. ► Composition analysis indicated DDT antifouling paint was the main source. ► High loading DDT in sediments resulted in high probability of ecological risks. ► Potential health risks for residents were mainly from the exposure of ingestion

The SOBANE risk management strategy and the Déparis method for the participatory screening of the risks.

Science.gov (United States)

Malchaire, J B

2004-08-01

The first section of the document describes a risk-prevention strategy, called SOBANE, in four levels: screening, observation, analysis and expertise. The aim is to make risk prevention faster, more cost effective, and more effective in coordinating the contributions of the workers themselves, their management, the internal and external occupational health (OH) practitioners and the experts. These four levels are: screening, where the risk factors are detected by the workers and their management, and obvious solutions are implemented; observation, where the remaining problems are studied in more detail, one by one, and the reasons and the solutions are discussed in detail; analysis, where, when necessary, an OH practitioner is called upon to carry out appropriate measurements to develop specific solutions; expertise, where, in very sophisticated and rare cases, the assistance of an expert is called upon to solve a particular problem. The method for the participatory screening of the risks (in French: Dépistage Participatif des Risques), Déparis, is proposed for the first level screening of the SOBANE strategy. The work situation is systematically reviewed and all the aspects conditioning the easiness, the effectiveness and the satisfaction at work are discussed, in search of practical prevention measures. The points to be studied more in detail at level 2, observation, are identified. The method is carried out during a meeting of key workers and technical staff. The method proves to be simple, sparing in time and means and playing a significant role in the development of a dynamic plan of risk management and of a culture of dialogue in the company.

Ecologic and Sociodemographic Risk Determinants for Dengue Transmission in Urban Areas in Thailand

Science.gov (United States)

Koyadun, Surachart; Butraporn, Piyarat; Kittayapong, Pattamaporn

2012-01-01

This study analyzed the association between household-level ecologic and individual-level sociodemographic determinants and dengue transmission in urban areas of Chachoengsao province, Thailand. The ecologic and sociodemographic variables were examined by univariate analysis and multivariate logistic regression. In the ecologic model, dengue risk was related to households situated in the ecotope of residential mixed with commercial and densely populated urban residential areas (RCDENPURA) (aOR = 2.23, P = 0.009), high historical dengue risk area (aOR = 2.06, P 45 years (aOR = 3.24, P = 0.003), secondary and higher educational degrees (aOR = 2.33, P = 0.013), household members >4 persons (aOR = 2.01, P = 0.02), and community effort in environmental management by clean-up campaign (aOR = 1.91, P = 0.035). It is possible that the preventive measures were positively correlated with dengue risk because these activities were generally carried out in particular households or communities following dengue experiences or dengue outbreaks. Interestingly, the ecotope of RCDENPURA and high historical dengue risk area appeared to be very good predictors of dengue incidences. PMID:23056042

Risks of Liver (Hepatocellular) Cancer Screening

Science.gov (United States)

... cancer. Having hepatitis or cirrhosis can increase the risk of developing liver cancer. Anything that increases the ... clinical trials is available from the NCI website . Risks of Liver (Hepatocellular) Cancer Screening Key Points Screening ...

Screening of Geomechanical Risks for Malaysian Development Field

Directory of Open Access Journals (Sweden)

Syed Najmuddin Syed Muhammad Syafiq

2017-01-01

Full Text Available Deeper drilling and exploitation of difficult reservoir is the new trend in oil and gas industry. Geomechanics study has, therefore, become a new requirement particularly for oil and gas field development. However, a complete geomechanics study is limited with the number of experts, time consuming and not a straightforward task. Therefore, there is an urgent need of a quick geomechanics screening criterion to be used as a standard guideline to evaluate the high level geomechanical risks and suitable analysis can be recommended for the identified development fields. The aim of this paper is to propose a screening criterion for geomechanical risks study based on four key parameters, drilling, depletion, injection and storage and sand production. The screening approach is designed based on Risk Assessment Matrix (RAM risk screening where the likelihood is based on a set of scores developed to specific questions. The consequence for each failure scenarios is assessed based on educated estimation of the impact towards people, asset, environment and reputation. Recommendations for geomechanical study are made based on the severity of each failure category on the RAM risk matrix. Fourteen development fields in offshore Peninsular Malaysia, offshore Sarawak and offshore Sabah are selected for the assessment. Based on results, fields in offshore Sarawak and Sabah have higher potential for geomechacnical issues mainly because of their geological settings and formation characteristics. A set of geomechanical study is proposed for each individual field for prudent management of potential geomechanics risk associated with the depletion and EOR injection scheme planned for the fields.

Regional scale ecological risk assessment: using the relative risk model

National Research Council Canada - National Science Library

Landis, Wayne G

2005-01-01

...) in the performance of regional-scale ecological risk assessments. The initial chapters present the methodology and the critical nature of the interaction between risk assessors and decision makers...

Nutritional Risk Screening 2002, Short Nutritional Assessment Questionnaire, Malnutrition Screening Tool, and Malnutrition Universal Screening Tool Are Good Predictors of Nutrition Risk in an Emergency Service.

Science.gov (United States)

Rabito, Estela Iraci; Marcadenti, Aline; da Silva Fink, Jaqueline; Figueira, Luciane; Silva, Flávia Moraes

2017-08-01

There is an international consensus that nutrition screening be performed at the hospital; however, there is no "best tool" for screening of malnutrition risk in hospitalized patients. To evaluate (1) the accuracy of the MUST (Malnutrition Universal Screening Tool), MST (Malnutrition Screening Tool), and SNAQ (Short Nutritional Assessment Questionnaire) in comparison with the NRS-2002 (Nutritional Risk Screening 2002) to identify patients at risk of malnutrition and (2) the ability of these nutrition screening tools to predict morbidity and mortality. A specific questionnaire was administered to complete the 4 screening tools. Outcomes measures included length of hospital stay, transfer to the intensive care unit, presence of infection, and incidence of death. A total of 752 patients were included. The nutrition risk was 29.3%, 37.1%, 33.6%, and 31.3% according to the NRS-2002, MUST, MST, and SNAQ, respectively. All screening tools showed satisfactory performance to identify patients at nutrition risk (area under the receiver operating characteristic curve between 0.765-0.808). Patients at nutrition risk showed higher risk of very long length of hospital stay as compared with those not at nutrition risk, independent of the tool applied (relative risk, 1.35-1.78). Increased risk of mortality (2.34 times) was detected by the MUST. The MUST, MST, and SNAQ share similar accuracy to the NRS-2002 in identifying risk of malnutrition, and all instruments were positively associated with very long hospital stay. In clinical practice, the 4 tools could be applied, and the choice for one of them should be made per the particularities of the service.

Occurrence and ecological risk assessment of emerging organic chemicals in urban rivers

DEFF Research Database (Denmark)

Peng, Fengjiao; Pan, Chang Gui; Zhang, Min

2017-01-01

at the suburb area. A screening-level risk assessment showed that 4-nonylphenol and triclosan (TCS) pose potential risks to aquatic organisms in most sampling sites. For individual taxa, 4-NP may pose risks to various groups of aquatic organisms, while TCS only might pose high risks to algae....

Haloacetic acids in the aquatic environment. Part II: ecological risk assessment

International Nuclear Information System (INIS)

Hanson, Mark L.; Solomon, Keith R.

2004-01-01

Haloacetic acids (HAAs) are environmental contaminants found in aquatic ecosystems throughout the world as a result of both anthropogenic and natural production. The ecological risk posed by these compounds to organisms in freshwater environments, with a specific focus on aquatic macrophytes, was characterized. The plants evaluated were Lemna gibba, Myriophyllum spicatum and M. sibiricum and the HAAs screened were monochloroacetic acid (MCA), dichloroacetic acid (DCA), trichloroacetic acid (TCA), trifluoroacetic acid (TFA) and chlorodifluoroacetic acid (CDFA). Laboratory toxicity data formed the basis of the risk assessment, but field studies were also utilized. The estimated risk was calculated using hazard quotients (HQ), as well as effect measure distributions (EMD) in a modified probabilistic ecological risk assessment. EMDs were used to estimate HAA thresholds of toxicity for use in HQ assessments. This threshold was found to be a more sensitive measure of low toxicity than the no observed effect concentrations (NOEC) or the effective concentration (EC 10 ). Using both deterministic and probabilistic methods, it was found that HAAs do not pose a significant risk to freshwater macrophytes at current environmental concentrations in Canada, Europe or Africa for both single compound and mixture exposures. Still, HAAs are generally found as mixtures and their potential interactions are not fully understood, rendering this phase of the assessment uncertain and justifying further effects characterization. TCA in some environments poses a slight risk to phytoplankton and future concentrations of TFA and CDFA are likely to increase due to their recalcitrant nature, warranting continued environmental surveillance of HAAs. - Current environmental concentrations of haloacetic acids do not pose a risk to aquatic macrophytes, but could impact plankton

Reevaluation of 1999 Health-Based Environmental Screening Levels (HBESLs) for Chemical Warfare Agents

Energy Technology Data Exchange (ETDEWEB)

Watson, Annetta Paule [ORNL; Dolislager, Fredrick G [ORNL

2007-05-01

This report evaluates whether new information and updated scientific models require that changes be made to previously published health-based environmental soil screening levels (HBESLs) and associated environmental fate/breakdown information for chemical warfare agents (USACHPPM 1999). Specifically, the present evaluation describes and compares changes that have been made since 1999 to U.S. Environmental Protection Agency (EPA) risk assessment models, EPA exposure assumptions, as well as to specific chemical warfare agent parameters (e.g., toxicity values). Comparison was made between screening value estimates recalculated with current assumptions and earlier health-based environmental screening levels presented in 1999. The chemical warfare agents evaluated include the G-series and VX nerve agents and the vesicants sulfur mustard (agent HD) and Lewisite (agent L). In addition, key degradation products of these agents were also evaluated. Study findings indicate that the combined effect of updates and/or changes to EPA risk models, EPA default exposure parameters, and certain chemical warfare agent toxicity criteria does not result in significant alteration to the USACHPPM (1999) health-based environmental screening level estimates for the G-series and VX nerve agents or the vesicant agents HD and L. Given that EPA's final position on separate Tier 1 screening levels for indoor and outdoor worker screening assessments has not yet been released as of May 2007, the study authors find that the 1999 screening level estimates (see Table ES.1) are still appropriate and protective for screening residential as well as nonresidential sites. As such, risk management decisions made on the basis of USACHPPM (1999) recommendations do not require reconsideration. While the 1999 HBESL values are appropriate for continued use as general screening criteria, the updated '2007' estimates (presented below) that follow the new EPA protocols currently under development

Prevalence of cardiovascular disease risk factors among a Nigerian adult population: Relationship with income level and accessibility to CVD risks screening

DEFF Research Database (Denmark)

Oguoma, Victor Maduabuchi; Nwose, Ezekiel Uba; Nwose, Ezekiel Uba

2015-01-01

males and 273 females) had mean age (± standard deviation) of 38.3 ± 20.5 and 42.9 ± 20.7 year s, respectively. Only total cholesterol (p = 0.001), triglyceride (p = 0.005), high density lipoprotein cholesterol (HDL) (p index (BMI) (p = 0.03) and average income rate (p = 0...... (p = 0.017), other CVD risk factors did not show a statistical significance across income levels. Participants with 'university and postgraduate education' had higher access to blood pressure and blood glucose screening compared to other educational groups; and this showed a statistical significance...

Determining significant endpoints for ecological risk analyses. 1997 annual progress report

Energy Technology Data Exchange (ETDEWEB)

Hinton, T.G.; Congdon, J.; Rowe, C.; Scott, D. [Univ. of Georgia, Aiken, SC (US). Savannah River Ecology Lab.; Bedford, J.; Whicker, F.W. [Colorado State Univ., Fort Collins, CO (US)

1997-11-01

'This report summarizes the first year''s progress of research funded under the Department of Energy''s Environmental Management Science Program. The research was initiated to better determine ecological risks from toxic and radioactive contaminants. More precisely, the research is designed to determine the relevancy of sublethal cellular damage to the performance of individuals and to identify characteristics of non-human populations exposed to chronic, low-level radiation, as is typically found on many DOE sites. The authors propose to establish a protocol to assess risks to non-human species at higher levels of biological organization by relating molecular damage to more relevant responses that reflect population health. They think that they can achieve this by coupling changes in metabolic rates and energy allocation patterns to meaningful population response variables, and by using novel biological dosimeters in controlled, manipulative dose/effects experiments. They believe that a scientifically defensible endpoint for measuring ecological risks can only be determined once its understood the extent to which molecular damage from contaminant exposure is detrimental at the individual and population levels of biological organization.'

Integrated presentation of ecological risk from multiple stressors

Science.gov (United States)

Goussen, Benoit; Price, Oliver R.; Rendal, Cecilie; Ashauer, Roman

2016-10-01

Current environmental risk assessments (ERA) do not account explicitly for ecological factors (e.g. species composition, temperature or food availability) and multiple stressors. Assessing mixtures of chemical and ecological stressors is needed as well as accounting for variability in environmental conditions and uncertainty of data and models. Here we propose a novel probabilistic ERA framework to overcome these limitations, which focusses on visualising assessment outcomes by construct-ing and interpreting prevalence plots as a quantitative prediction of risk. Key components include environmental scenarios that integrate exposure and ecology, and ecological modelling of relevant endpoints to assess the effect of a combination of stressors. Our illustrative results demonstrate the importance of regional differences in environmental conditions and the confounding interactions of stressors. Using this framework and prevalence plots provides a risk-based approach that combines risk assessment and risk management in a meaningful way and presents a truly mechanistic alternative to the threshold approach. Even whilst research continues to improve the underlying models and data, regulators and decision makers can already use the framework and prevalence plots. The integration of multiple stressors, environmental conditions and variability makes ERA more relevant and realistic.

Integrated presentation of ecological risk from multiple stressors.

Science.gov (United States)

Goussen, Benoit; Price, Oliver R; Rendal, Cecilie; Ashauer, Roman

2016-10-26

Current environmental risk assessments (ERA) do not account explicitly for ecological factors (e.g. species composition, temperature or food availability) and multiple stressors. Assessing mixtures of chemical and ecological stressors is needed as well as accounting for variability in environmental conditions and uncertainty of data and models. Here we propose a novel probabilistic ERA framework to overcome these limitations, which focusses on visualising assessment outcomes by construct-ing and interpreting prevalence plots as a quantitative prediction of risk. Key components include environmental scenarios that integrate exposure and ecology, and ecological modelling of relevant endpoints to assess the effect of a combination of stressors. Our illustrative results demonstrate the importance of regional differences in environmental conditions and the confounding interactions of stressors. Using this framework and prevalence plots provides a risk-based approach that combines risk assessment and risk management in a meaningful way and presents a truly mechanistic alternative to the threshold approach. Even whilst research continues to improve the underlying models and data, regulators and decision makers can already use the framework and prevalence plots. The integration of multiple stressors, environmental conditions and variability makes ERA more relevant and realistic.

Risk of breast cancer after false-positive results in mammographic screening

DEFF Research Database (Denmark)

Roman, Marta; Castells, Xavier; Hofvind, Solveig

2016-01-01

risk (RR) of screen-detected cancer for women with false-positive versus negative results. We analyzed information from 1,935,093 women 50–69 years who underwent 6,094,515 screening exams. During an average 5.8 years of follow-up, 230,609 (11.9%) women received a false-positive result and 27,849 (1......Women with false-positive results are commonly referred back to routine screening. Questions remain regarding their long-term outcome of breast cancer. We assessed the risk of screen-detected breast cancer in women with false-positive results. We conducted a joint analysis using individual level.......4%) were diagnosed with screen-detected cancer. The adjusted RR of screen-detected cancer after a false-positive result was 2.01 (95% CI: 1.93–2.09). Women who tested false-positive at first screen had a RR of 1.86 (95% CI: 1.77–1.96), whereas those who tested false-positive at third screening had a RR...

Geographic variation and effect of area-level poverty rate on colorectal cancer screening

Directory of Open Access Journals (Sweden)

Schootman Mario

2008-10-01

Full Text Available Abstract Background With a secular trend of increasing colorectal cancer (CRC screening, concerns about disparities in CRC screening also have been rising. It is unclear if CRC screening varies geographically, if area-level poverty rate affects CRC screening, and if individual-level characteristics mediate the area-level effects on CRC screening. Methods Using 2006 Missouri Behavioral Risk Factor Surveillance System (BRFSS data, a multilevel study was conducted to examine geographic variation and the effect of area-level poverty rate on CRC screening use among persons age 50 or older. Individuals were nested within ZIP codes (ZIP5 areas, which in turn, were nested within aggregations of ZIP codes (ZIP3 areas. Six groups of individual-level covariates were considered as potential mediators. Results An estimated 51.8% of Missourians aged 50 or older adhered to CRC screening recommendations. Nearly 15% of the total variation in CRC screening lay between ZIP5 areas. Persons residing in ZIP5 areas with ≥ 10% of poverty rate had lower odds of CRC screening use than those residing in ZIP5 areas with Conclusion Large geographic variation of CRC screening exists in Missouri. Area-level poverty rate, independent of individual-level characteristics, is a significant predictor of CRC screening, but it only explains a small portion of the geographic heterogeneity of CRC screening. Individual-level factors we examined do not mediate the effect of the area-level poverty rate on CRC screening. Future studies should identify other area- and individual-level characteristics associated with CRC screening in Missouri.

Use of an integrated human health/ecological risk assessment to develop a long-term groundwater/site management plan for a sour gas facility

International Nuclear Information System (INIS)

Swanson, S.M.; Shaw, R.D.; McClymont, G.; Nadeau, S.

1995-01-01

An integrated human health and ecological risk assessment was used to quantify the level of risk associated with the off-site movement of contaminants via groundwater and soils at a medium-sized gas processing facility in southern Alberta. The study incorporated three key aspects: (1) integration; (2) consultation; and, (3) pro-active remedial actions. Integration was complete, beginning with the Problem Formulation stage and progressing through Risk Characterization and Risk Management. This integration was reflected in a multidisciplinary team of hydrogeologists, biologists and human health specialists. Several lessons emerged from the integrated approach: (1) spending 2/3 of the time and resources on Problem Formulation prevented later problems; (2) the different perspectives provided by the various specialists helped reveal the relative importance of pathways and ecological receptors (3) clear, consistent screening procedures for contaminants of concern and receptors were very effective with stakeholders; (4) exposure scenarios that incorporated common-sense situations (although still conservative) contributed to the credibility of the risk analysis; and, (5) an innovative combination of toxicity testing and chemical analysis helped delineate the boundaries of the potentially contaminated area for both human and ecological receptors in a cost effective manner. Consultation included directly affected parties, regulatory personnel and community members. The consultation extended through the project, with key ''buy-in'' points during Problem Formulation and Risk Characterization/Management. Pro-active remedial action included the removal of contaminant sources in the 1980's, a pump-and-treat system and extensive monitoring. These actions showed commitment and set the stage for credible risk-based mitigation and long-term monitoring

Environmental risk of climate change and groundwater abstraction on stream ecological conditions

DEFF Research Database (Denmark)

Seaby, Lauren Paige; Bøgh, Eva; Jensen, Niels H.

with DAISY, a one dimensional crop model describing soil water dynamics in the root zone, and MIKE SHE, a distributed groundwater-surface water model. The relative and combined impacts on low flows, groundwater levels, and nitrate leaching are quantified and compared to assess the water resource sensitivity...... and risk to stream ecological conditions. We find low flow and annual discharge to be most impacted by scenarios of climate change, with high variation across climate models (+/- 40% change). Doubling of current groundwater abstraction rates reduces annual discharge by approximately 20%, with higher...... flows and groundwater levels are of interest, as they relate to aquatic habitat and nitrate leaching, respectively. This study evaluates the risk to stream ecological conditions for a lowland Danish catchment under multiple scenarios of climate change and groundwater abstraction. Projections of future...

[Ecological risk evaluation of heavy metals of the typical dredged mud in Shanghai].

Science.gov (United States)

Tang, Qing-Li; Cheng, Jin-Ping; Gao, Hao-Min; Yao, Lei; Jiang, Zhen-Yi; Wu, Yang; Xie, Cui-Song; Liang, Hai; Wang, He; Pi, Shuai-Shuai; Yu, Zhao-Yi

2013-04-01

In order to discuss the potential ecological risk of heavy metals of the typical dredged mud in Shanghai, the Hakanson potential ecological risks method was used to analyse and assess the potential ecological risks of heavy metals, including Hg, Cd, Cu, Pb, As,Cr and Zn in dredged mud from the following three areas-the dock apron of Huangpu River, the mouth of the Yangtze River and inland waterways. The results showed that the mean values of ecological risk index (Er(i)) of the seven heavy metals are 20.05, 17.49, 8.82, 5.71, 4.68, 1.74 and 1.13, respectively, all of which belonged to the low ecological risk; Cd (one location in inland waterways) and Hg (three locations in the mouth of the Yangtze River and one location in inland waterways) are the most hazardous elements, with the Er(i) > 40, which belonged to the medium ecological risk or the high ecological risk, and other elements belonged to the low ecological risk. From the results of ecological risk indices(ERI) of the heavy metals in Shanghai dredged mud, the risk of the heavy metals belonged to the low ecological risk. The ERI of inland waterways, the mouth of the Yangtze River and the dock apron of the Huangpu River were 81.4, 57.7 and 52.5, respectively, which all belong to the low ecological risk.

Higher tier field research in ecological risk assessment: a case study

Energy Technology Data Exchange (ETDEWEB)

Faber, J. [Alterra, Wageningen (Netherlands)

2003-07-01

A newly developed basic procedure for site-specific ecological risk assessment in The Netherlands was followed in practice for the first time. In line with conventional Triade approaches, the procedure includes multidisciplinary parameters from environmental chemistry, toxicology and ecology to provide multiple weight of evidence. However, land use at the contaminated site and its vicinity is given more importance, and research parameters are selected in accordance to specific objectives for land use in order to test for harmful effects to underlying ecosystem services. Moreover, the approach is characterized by repetitive interactions between stakeholders and researching consultants, in particular with respect to the choice of parameters and criteria to assess the results. The approach was followed in an ecological risk assessment to test the assumptions underlying a soil management plant for a rural area in The Netherlands, called 'Krimpenerwaard'. Throughout this region some 5000 polder ditches have been filled with waste materials originating from local households, waterway sludge, industrial wastes, car shredders, and more. Several sites are severely polluted by heavy metals, cyanide, PAH or chlorinated hydrocarbons and require remediation or clean up. However, the exact distribution of these wastes over the entire region is scarcely known, and the Krimpenerwaard as a whole is treated as one case of serious soil pollution. A soil management plan was constructed by 13 stakeholding parties, aiming for a 'functional clean up' in view of land use, by means of covering 'suspected' categories of wastes with a 30-cm layer of local type soil. The ecological risk assessment aims to verify the assumptions in the soil management plan regarding the prevention of possible undesirable effects induced by the various waste materials. A tiered approach is followed, including a screening for bioavailable contaminants, a testing for general effects

Mechanistic modeling for mammography screening risks

International Nuclear Information System (INIS)

Bijwaard, Harmen

2008-01-01

Full text: Western populations show a very high incidence of breast cancer and in many countries mammography screening programs have been set up for the early detection of these cancers. Through these programs large numbers of women (in the Netherlands, 700.000 per year) are exposed to low but not insignificant X-ray doses. ICRP based risk estimates indicate that the number of breast cancer casualties due to mammography screening can be as high as 50 in the Netherlands per year. The number of lives saved is estimated to be much higher, but for an accurate calculation of the benefits of screening a better estimate of these risks is indispensable. Here it is attempted to better quantify the radiological risks of mammography screening through the application of a biologically based model for breast tumor induction by X-rays. The model is applied to data obtained from the National Institutes of Health in the U.S. These concern epidemiological data of female TB patients who received high X-ray breast doses in the period 1930-1950 through frequent fluoroscopy of their lungs. The mechanistic model that is used to describe the increased breast cancer incidence is based on an earlier study by Moolgavkar et al. (1980), in which the natural background incidence of breast cancer was modeled. The model allows for a more sophisticated extrapolation of risks to the low dose X-ray exposures that are common in mammography screening and to the higher ages that are usually involved. Furthermore, it allows for risk transfer to other (non-western) populations. The results have implications for decisions on the frequency of screening, the number of mammograms taken at each screening, minimum and maximum ages for screening and the transfer to digital equipment. (author)

Technical challenges in the qualitative ecological risk assessments performed on the Hanford Site operable units

International Nuclear Information System (INIS)

Probasco, K.M.

1994-01-01

Qualitative Risk Assessments (QRAS) have been selected as the method for providing the risk-driver indications for interim, remedial, and cleanup actions for the Hanford Site operable units' ecological risk assessments. This expedited response action path has been developed for the Hanford Site to facilitate time-critical decisions and generate immediate emergency cleanup actions. Tight budgets and aggressive time schedules are a major factor in the development of the QRA process. The QRA is a quick way to find immediate threats and a good precursor to a full risk assessment. However, numerous technical challenges have been identified with the QRA approach. The QRA approach differs from a baseline risk assessment in several ways. The main differences involve the use of data that have previously been gathered from the site, and the development of a ''bias-for-action'' document that would reveal qualitative risks from the contaminants identified at the operable units. Technical challenges concerning the ecological portion of these QRAs have raised questions about using the ORA for decision-making and may have weakened the validity of its use in the established procedural framework. Challenges involving such issues as the extrapolation of the contaminant data, data validation and screening techniques, receptor selections, and the final risk characterization outcome threaten the feasibility of the QRA as a decision-making tool. This discussion provides insight into resolving technical challenges and may be a ''lessons-learned'' device for those interested in the QRA approach. Ultimately, these challenges are proving to be learning tools for scientists, regulators, and ecologists and are identifying the data gaps and research direction for future ecological baseline risk assessments

Risk of breast cancer after false-positive results in mammographic screening.

Science.gov (United States)

Román, Marta; Castells, Xavier; Hofvind, Solveig; von Euler-Chelpin, My

2016-06-01

Women with false-positive results are commonly referred back to routine screening. Questions remain regarding their long-term outcome of breast cancer. We assessed the risk of screen-detected breast cancer in women with false-positive results. We conducted a joint analysis using individual level data from the population-based screening programs in Copenhagen and Funen in Denmark, Norway, and Spain. Overall, 150,383 screened women from Denmark (1991-2008), 612,138 from Norway (1996-2010), and 1,172,572 from Spain (1990-2006) were included. Poisson regression was used to estimate the relative risk (RR) of screen-detected cancer for women with false-positive versus negative results. We analyzed information from 1,935,093 women 50-69 years who underwent 6,094,515 screening exams. During an average 5.8 years of follow-up, 230,609 (11.9%) women received a false-positive result and 27,849 (1.4%) were diagnosed with screen-detected cancer. The adjusted RR of screen-detected cancer after a false-positive result was 2.01 (95% CI: 1.93-2.09). Women who tested false-positive at first screen had a RR of 1.86 (95% CI: 1.77-1.96), whereas those who tested false-positive at third screening had a RR of 2.42 (95% CI: 2.21-2.64). The RR of breast cancer at the screening test after the false-positive result was 3.95 (95% CI: 3.71-4.21), whereas it decreased to 1.25 (95% CI: 1.17-1.34) three or more screens after the false-positive result. Women with false-positive results had a twofold risk of screen-detected breast cancer compared to women with negative tests. The risk remained significantly higher three or more screens after the false-positive result. The increased risk should be considered when discussing stratified screening strategies. © 2016 The Authors. Cancer Medicine published by John Wiley & Sons Ltd.

A Comparison of Microplastic Ecological Risk in Sediments of Shanghai and Hong Kong Based on the Ecological Risk Index and Plastic Hazard Classes

Science.gov (United States)

Xu, P.; Li, D.

2017-12-01

Microplastic which refers to the plastic fragments and particles with diameters less than 5 mm has potential threatening impacts on various ambient medium. The shortage of knowledge of ecological risks from microplastics inhibits the scientific research process. Based on the research of the literature widely, this paper analyzed potential ecological risk of microplastic in sediment of Shanghai and Hong Kong by means of ecological risk index and hazard classes developed by UN Globally Harmonized System. Combining of the two assessment method, results showed that the order of microplastic pollution extents in sediments was Changjiang Estuary

Fuzzy Comprehensive Evaluation of Ecological Risk Based on Cloud Model: Taking Chengchao Iron Mine as Example

Science.gov (United States)

Ruan, Jinghua; Chen, Yong; Xiao, Xiao; Yong, Gan; Huang, Ranran; Miao, Zuohua

2018-01-01

Aimed at the fuzziness and randomness during the evaluation process, this paper constructed a fuzzy comprehensive evaluation method based on cloud model. The evaluation index system was established based on the inherent risk, present level and control situation, which had been proved to be able to convey the main contradictions of ecological risk in mine on the macro level, and be advantageous for comparison among mines. The comment sets and membership functions improved by cloud model could reflect the uniformity of ambiguity and randomness effectively. In addition, the concept of fuzzy entropy was introduced to further characterize the fuzziness of assessments results and the complexities of ecological problems in target mine. A practical example in Chengchao Iron Mine evidenced that, the assessments results can reflect actual situations appropriately and provide a new theoretic guidance for comprehensive ecological risk evaluation of underground iron mine.

Development of Triad approach based system for ecological risk assessment for contaminated areas of Kyrgyzstan

Science.gov (United States)

Kydralieva, Kamilia; Uzbekov, Beksultan; Khudaibergenova, Bermet; Terekhova, Vera; Jorobekova, Sharipa

2014-05-01

substances), 2) ecological parameters (assessing changes in microorganism's community structure and functions, bioindication); and 3) toxicological bioassays (utilizing classical endpoints such as survival and reproduction rates, genotoxicity). The output will be consisted of 3 indexes: 1) Environmental Risk Index, quantifying the level of biological damage at population-community level, 2) Biological Vulnerability Index, assessing the potential threats to biological equilibria, and 3) Genotoxicity Index, screening genotoxic effects. Multi-criteria Decision Analysis (MCDA) will be used to integrate a set of environmental Triad data to be obtained during the project, which will be carried out in order to estimate the potential risk from soil contamination of the highly anthropized areas of Kadzhi-Say, which have been impacted by deposition of heavy metals. The basis of the development under this research is studies with a particular focus concerning the biocenosis mapping of Kyrgyz soils (Mamytova et al., 2003, 2010), investigations on interaction of humic substances with soil contaminants (Jorobekova, Kydralieva, Khudaibergenova, 2004; Khudaibergenova, 2005, 2007), and in addition, technical approach for ecotoxicological assessment of soils (Terekhova, 2007, 2011). Soil ecotoxicological estimation has been studied with a battery of tests using test-organisms of many trophic levels. Currently, bioindication of soils with various humus states is under study (Senesi, Yakimenko 2007; Yakimenko, et al., 2008).

DEVELOPMENT OF A RISK SCREENING METHOD FOR CREDITED OPERATOR ACTIONS

International Nuclear Information System (INIS)

HIGGINS, J.C.; O'HARA, J.M.; LEWIS, P.M.; PERSENSKY, J.; BONGARRA, J.

2002-01-01

DEVELOPMENT OF A RISK SCREENING METHOD FOR CREDITED OPERATOR ACTIONS. THE U.S. NUCLEAR REGULATORY COMMISSION (NRC) REVIEWS THE HUMAN FACTORS ASPECTS OF PROPOSED LICENSE AMENDMENTS THAT IMPACT HUMAN ACTIONS THAT ARE CREDITED IN A PLANTS SAFETY ANALYSIS. THE STAFF IS COMMITTED TO A GRADED APPROACH TO THESE REVIEWS THAT FOCUS RESOURCES ON THE MOST RISK IMPORTANT CHANGES. THEREFORE, A RISK INFORMED SCREENING METHOD WAS DEVELOPED BASED ON AN ADAPTATION OF EXISTING GUIDANCE FOR RISK INFORMED REGULATION AND HUMAN FACTORS. THE METHOD USES BOTH QUANTITATIVE AND QUALITATIVE INFORMATION TO DIVIDE THE AMENDMENT REQUESTS INTO DIFFERENT LEVELS OF REVIEW. THE METHOD WAS EVALUATED USING A VARIETY OF TESTS. THIS PAPER WILL SUMMARIZE THE DEVELOPMENT OF THE METHODOLOGY AND THE EVALUATIONS THAT WERE PERFORMED TO VERIFY ITS USEFULNESS

Ecological risk evaluation of sediment core samples, Lake Tortum (Erzurum, NE Turkey using environmental indices

Directory of Open Access Journals (Sweden)

Hakan Kaya

2017-11-01

Full Text Available This study aimed to determine the vertical distribution of heavy metals in a 72 cm-long core sample from Lake Tortum in order to shed light on the implications of potential ecological risks. Analysis was based on the use of environmental indices such as the Integrated Pollution Load Index (PLI and Potential Ecological Risk Index (PER. Results reveal that, except for Pb, Mn and Hg, the lowest concentrations of heavy metals occur at a core depth of between 2 cm and 20 cm for Cu, Zn, Ni, Fe, As, Cd, Cr and Al. The highest concentration was found at sampling intervals of 36 cm and 50 cm, with the exception of Pb, Mn, Hg and Ni. The PLI values from bottom to top are less than 1 while the level with the nearest value to the background value lies at a depth between 24 cm and 26 cm. The PER index results suggest a low ecological risk level for Cu, Pb, Zn, Ni, Mn, Fe, As, Cr, and Al; however, Cd and Hg constitute an ecological threat to the lake ecosystem.

Climate risk screening tools and their application: A guide to the guidance

Energy Technology Data Exchange (ETDEWEB)

Traerup, S.; Olhoff, A.

2011-07-01

Climate risk screening is an integral part of efforts to ascertain current and future vulnerabilities and risks related to climate change. It is a prerequisite for identifying and designing adaptation measures, and an important element in the process of integrating, or mainstreaming, climate change adaptation into development project, planning and policy processes. There is an increasing demand and attention among national stakeholders in developing countries to take into account potential implications of climate variability and change for planning and prioritizing of development strategies and activities. Subsequently, there is a need for user friendly guidance on climate risk screening tools and their potentials for application that targets developing country stakeholders. This need is amplified by the sheer volume of climate change mainstreaming guidance documents and risk screening and assessment tools available and currently under development. Against this background, this paper sets out to provide potential users in developing countries, including project and programme developers and managers, with an informational entry point to climate risk screening tools. The emphasis in this report is on providing: 1) An overview of available climate risk screening and assessment tools along with indications of the tools available and relevant for specific purposes and contexts (Section 3). 2) Examples of application of climate risk screening and assessment tools along with links to further information (Section 4). Before turning to the respective sections on available climate risk screening tools and examples of their application, a delimitation of the tools included in this paper is included in Section 2. This section also provides a brief overview of how climate screening and related tools fit into decision making steps at various planning and decision making levels in conjunction with an outline of overall considerations to make when choosing a tool. The paper is

Probabilistic ecological risk assessment of polycyclic aromatic hydrocarbons in southwestern catchments of the Bohai Sea, China.

Science.gov (United States)

Zeng, Lin; Zeng, Siyu; Dong, Xin; Zhang, Tianzhu; Chen, Jining

2013-10-01

A probability risk assessment was undertaken to study the individual and combined ecological risks induced by six polycyclic aromatic hydrocarbons (PAHs) both in surface water and sediment from southwestern catchments of the Bohai Sea, China. The actual measured PAH concentrations in water and sediment were compared with toxicity effect data (the 10th percentile of predicted no effect concentration) to calculate the risk quotients (RQs) for an individual PAH. The equilibrium partitioning method was applied to estimate toxicity data in sediment. A method based on the equivalent concentration concept was proposed and applied to assess the combined ecological risk of multiple PAHs. Monte Carlo simulation and bootstrap technique were utilized to calculate the distribution of RQs and associated uncertainties. The ecological safety level was defined by RQ ≤ 1. Results indicated that both in water and sediment, fluoranthene and pyrene posed the highest risks, whereas acenaphthene and fluorene posed negligible risks. Naphthalene and phenanthrene did not pose risks to the ecological community in surface water but had relatively higher risks in sediment. The median RQs of combined risk in surface water and sediment were 0.934 and 2.42, and the probabilities of RQ > 1 were up to 0.473 and 0.599, respectively, which were much higher than the individual compound acting alone. The risk level in sediment was quite higher than in surface water probably owing to the non-equilibrium distribution between two phases, which suggested that local authorities should focus more on sediment quality management.

Mechanistic effect modeling for ecological risk assessment: where to go from here?

Science.gov (United States)

Grimm, Volker; Martin, Benjamin T

2013-07-01

Mechanistic effect models (MEMs) consider the mechanisms of how chemicals affect individuals and ecological systems such as populations and communities. There is an increasing awareness that MEMs have high potential to make risk assessment of chemicals more ecologically relevant than current standard practice. Here we discuss what kinds of MEMs are needed to improve scientific and regulatory aspects of risk assessment. To make valid predictions for a wide range of environmental conditions, MEMs need to include a sufficient amount of emergence, for example, population dynamics emerging from what individual organisms do. We present 1 example where the life cycle of individuals is described using Dynamic Energy Budget theory. The resulting individual-based population model is thus parameterized at the individual level but correctly predicts multiple patterns at the population level. This is the case for both control and treated populations. We conclude that the state-of-the-art in mechanistic effect modeling has reached a level where MEMs are robust and predictive enough to be used in regulatory risk assessment. Mechanistic effect models will thus be used to advance the scientific basis of current standard practice and will, if their development follows Good Modeling Practice, be included in a standardized way in future regulatory risk assessments. Copyright © 2013 SETAC.

Use of traits-based bioassessment approaches in biomonitoring and ecological risk assessment

NARCIS (Netherlands)

Brink, van den P.J.; Alexander, A.; Desrosiers, M.; Goedkoop, W.; Goethals, P.L.M.; Liess, M.; Dyer, S.

2011-01-01

We discuss the application of traits-based bioassessment approaches in retrospective bioassessment as well as in prospective ecological risk assessments in regulatory frameworks. Both approaches address the interaction between species and stressors and their consequences at different levels of

Ecosystem services as assessment endpoints for ecological risk assessment.

Science.gov (United States)

Munns, Wayne R; Rea, Anne W; Suter, Glenn W; Martin, Lawrence; Blake-Hedges, Lynne; Crk, Tanja; Davis, Christine; Ferreira, Gina; Jordan, Steve; Mahoney, Michele; Barron, Mace G

2016-07-01

Ecosystem services are defined as the outputs of ecological processes that contribute to human welfare or have the potential to do so in the future. Those outputs include food and drinking water, clean air and water, and pollinated crops. The need to protect the services provided by natural systems has been recognized previously, but ecosystem services have not been formally incorporated into ecological risk assessment practice in a general way in the United States. Endpoints used conventionally in ecological risk assessment, derived directly from the state of the ecosystem (e.g., biophysical structure and processes), and endpoints based on ecosystem services serve different purposes. Conventional endpoints are ecologically important and susceptible entities and attributes that are protected under US laws and regulations. Ecosystem service endpoints are a conceptual and analytical step beyond conventional endpoints and are intended to complement conventional endpoints by linking and extending endpoints to goods and services with more obvious benefit to humans. Conventional endpoints can be related to ecosystem services even when the latter are not considered explicitly during problem formulation. To advance the use of ecosystem service endpoints in ecological risk assessment, the US Environmental Protection Agency's Risk Assessment Forum has added generic endpoints based on ecosystem services (ES-GEAE) to the original 2003 set of generic ecological assessment endpoints (GEAEs). Like conventional GEAEs, ES-GEAEs are defined by an entity and an attribute. Also like conventional GEAEs, ES-GEAEs are broadly described and will need to be made specific when applied to individual assessments. Adoption of ecosystem services as a type of assessment endpoint is intended to improve the value of risk assessment to environmental decision making, linking ecological risk to human well-being, and providing an improved means of communicating those risks. Integr Environ Assess Manag

Ecological risk assessment and natural resource management on the Outer Continental Shelf

International Nuclear Information System (INIS)

Goeke, G.; Roscigno, P.F.

1993-01-01

Since 1988 beginning with the Drilling Impact Assessment Task Force, Minerals Management Service (MMS) has used formal risk analysis methodologies in the Gulf of Mexico to determine the potential impact of gas and oil activities son natural resources. In the process, a list of assumptions, critical for the assessment of potential impacts, was generated. These assumptions were incorporated into a scenario where several levels of certainty described the hazards in terms of expected frequency of effects and the seriousness of the consequences. A risk matrix was generated from these assumptions and was used to generate a risk assessment for the various impact-producing factors on ecological endpoints. Recommendations for risk management were also provided so that decision-makers were given insight into acceptable/unacceptable levels of risk. This process insured that those issues with the highest potential impact were given the highest priority in terms of resources. One of the most important aspect so f the development of a risk assessment was determining the frequency of effects of the impact-producing factors. A paucity of data concerning the effects of impact-producing factors on estuarine and marine ecosystems remains the primary limiting factor in the development of ecological risk assessments. Presented here is a broad outline of the risk assessment methodology using chemosynthetic communities found in the Gulf of Mexico as an example

Heavy metal enrichment and ecological risk assessment of surface sediments in Khorramabad River, West Iran.

Science.gov (United States)

Rastmanesh, F; Safaie, S; Zarasvandi, A R; Edraki, M

2018-04-11

The ecological health of rivers has often been threatened in urbanized catchments due to the expansion of industrial activities and the population growth. Khorramabad River which flows through Khorramabad city, west of Iran, is an example of such settings. The river water is used for agricultural purposes downstream. In this study, the effect of Khorramabad city on heavy metal and metalloid (Cu, Pb, Zn, Ni, Cr, and As) loads in Khorramabad River sediments was investigated. To evaluate sediment pollution and potential adverse biological effects, surface sediment samples were collected at selected locations along the river and were characterized for their geochemical properties. Contamination factor (CF), pollution load index (PLI), and ecological risk assessment (RI) were calculated. Also, sediment quality guidelines (SQGs) were used to screen contaminants of concern in the study area. The results showed that sediments were moderately polluted, with stations located in more densely populated areas showing higher pollution indicators. Copper, Zn, and Pb sources could be attributed to urban wastewater, whereas Ni, Cr, and As had both natural and anthropogenic sources. Moreover, ecological risk assessments showed that sediments could be classified in the category of low risk. The results of the present study showed the effect of anthropogenic activities on heavy metal loads of the river sediments and these findings can be used to mitigate potential impacts on the environment and human health.

The cumulative risk of false-positive screening results across screening centres in the Norwegian Breast Cancer Screening Program

Energy Technology Data Exchange (ETDEWEB)

Roman, M., E-mail: Marta.Roman@kreftregisteret.no [Cancer Registry of Norway, Oslo (Norway); Department of Women and Children’s Health, Oslo University Hospital, Oslo (Norway); Skaane, P., E-mail: PERSK@ous-hf.no [Department of Radiology, Oslo University Hospital Ullevaal, University of Oslo, Oslo (Norway); Hofvind, S., E-mail: Solveig.Hofvind@kreftregisteret.no [Cancer Registry of Norway, Oslo (Norway); Oslo and Akershus University College of Applied Sciences, Faculty of Health Science, Oslo (Norway)

2014-09-15

Highlights: • We found variation in early performance measures across screening centres. • Radiologists’ performance may play a key role in the variability. • Potential to improve the effectiveness of breast cancer screening programs. • Continuous surveillance of screening centres and radiologists is essential. - Abstract: Background: Recall for assessment in mammographic screening entails an inevitable number of false-positive screening results. This study aimed to investigate the variation in the cumulative risk of a false positive screening result and the positive predictive value across the screening centres in the Norwegian Breast Cancer Screening Program. Methods: We studied 618,636 women aged 50–69 years who underwent 2,090,575 screening exams (1996–2010. Recall rate, positive predictive value, rate of screen-detected cancer, and the cumulative risk of a false positive screening result, without and with invasive procedures across the screening centres were calculated. Generalized linear models were used to estimate the probability of a false positive screening result and to compute the cumulative false-positive risk for up to ten biennial screening examinations. Results: The cumulative risk of a false-positive screening exam varied from 10.7% (95% CI: 9.4–12.0%) to 41.5% (95% CI: 34.1–48.9%) across screening centres, with a highest to lowest ratio of 3.9 (95% CI: 3.7–4.0). The highest to lowest ratio for the cumulative risk of undergoing an invasive procedure with a benign outcome was 4.3 (95% CI: 4.0–4.6). The positive predictive value of recall varied between 12.0% (95% CI: 11.0–12.9%) and 19.9% (95% CI: 18.3–21.5%), with a highest to lowest ratio of 1.7 (95% CI: 1.5–1.9). Conclusions: A substantial variation in the performance measures across the screening centres in the Norwegian Breast Cancer Screening Program was identified, despite of similar administration, procedures, and quality assurance requirements. Differences in the

The cumulative risk of false-positive screening results across screening centres in the Norwegian Breast Cancer Screening Program

International Nuclear Information System (INIS)

Roman, M.; Skaane, P.; Hofvind, S.

2014-01-01

Highlights: • We found variation in early performance measures across screening centres. • Radiologists’ performance may play a key role in the variability. • Potential to improve the effectiveness of breast cancer screening programs. • Continuous surveillance of screening centres and radiologists is essential. - Abstract: Background: Recall for assessment in mammographic screening entails an inevitable number of false-positive screening results. This study aimed to investigate the variation in the cumulative risk of a false positive screening result and the positive predictive value across the screening centres in the Norwegian Breast Cancer Screening Program. Methods: We studied 618,636 women aged 50–69 years who underwent 2,090,575 screening exams (1996–2010. Recall rate, positive predictive value, rate of screen-detected cancer, and the cumulative risk of a false positive screening result, without and with invasive procedures across the screening centres were calculated. Generalized linear models were used to estimate the probability of a false positive screening result and to compute the cumulative false-positive risk for up to ten biennial screening examinations. Results: The cumulative risk of a false-positive screening exam varied from 10.7% (95% CI: 9.4–12.0%) to 41.5% (95% CI: 34.1–48.9%) across screening centres, with a highest to lowest ratio of 3.9 (95% CI: 3.7–4.0). The highest to lowest ratio for the cumulative risk of undergoing an invasive procedure with a benign outcome was 4.3 (95% CI: 4.0–4.6). The positive predictive value of recall varied between 12.0% (95% CI: 11.0–12.9%) and 19.9% (95% CI: 18.3–21.5%), with a highest to lowest ratio of 1.7 (95% CI: 1.5–1.9). Conclusions: A substantial variation in the performance measures across the screening centres in the Norwegian Breast Cancer Screening Program was identified, despite of similar administration, procedures, and quality assurance requirements. Differences in the

Multi-Target Risk Assessment of Potentially Toxic Elements in Farmland Soil Based on the Environment-Ecological-Health Effect.

Science.gov (United States)

Wang, Zhongyang; Meng, Bo; Zhang, Wei; Bai, Jinheng; Ma, Yingxin; Liu, Mingda

2018-05-28

There are potential impacts of Potentially Toxic Elements (PTEs) (e.g., Cd, Cr, Ni, Cu, As, Zn, Hg, and Pb) in soil from the perspective of the ecological environment and human health, and assessing the pollution and risk level of soil will play an important role in formulating policies for soil pollution control. Lingyuan, in the west of Liaoning Province, China, is a typical low-relief terrain of a hilly area. The object of study in this research is the topsoil of farmland in this area, of which 71 soil samples are collected. In this study, research methods, such as the Nemerow Index, Potential Ecological Hazard Index, Ecological Risk Quotient, Environmental Exposure Hazard Analysis, Positive Matrix Factorization Model, and Land Statistical Analysis, are used for systematical assessment of the pollution scale, pollution level, and source of PTEs, as well as the ecological environmental risks and health risks in the study area. The main conclusions are: The average contents of As, Cd, Cr, Cu, Hg, Zn, Ni, and Pb of the soil are 5.32 mg/kg, 0.31 mg/kg, 50.44 mg/kg, 47.05 mg/kg, 0.03 mg/kg, 79.36 mg/kg, 26.01 mg/kg, and 35.65 mg/kg, respectively. The contents of Cd, Cu, Zn, and Pb exceed the background value of local soil; Cd content of some study plots exceeds the National Soil Environmental Quality Standard Value (0.6 mg/kg), and the exceeding standard rate of study plots is 5.63%; the comprehensive potential ecological hazard assessment in the study area indicates that the PTEs are at a slight ecological risk; probabilistic hazard quotient assessment indicates that the influence of PTEs on species caused by Cu is at a slight level ( p = 10.93%), and Zn, Pb, and Cd are at an acceptable level. For the ecological process, Zn is at a medium level ( p = 25.78%), Cu is at a slight level (19.77%), and the influence of Cd and Pb are acceptable; human health hazard assessment states that the Non-carcinogenic comprehensive health hazard index HI = 0.16 natural source are 13

[Heavy Metals Pollution in Topsoil from Dagang Industry Area and Its Ecological Risk Assessment].

Science.gov (United States)

Zhang, Qian; Chen, Zong-juan; Peng, Chang-sheng; Li, Fa-sheng; Gu, Qing-bao

2015-11-01

Based on previous studies and field investigation of Dagang industry area in Tianjin, a total of 128 topsoil samples were collected, and contents of 10 heavy metals (As, Cd, Cr, Co, Cu, Pb, Ni, V, Zn and Hg) were determined. The geoaccumulation index and geostatistics were applied to examine the degree of contamination and spatial distribution of heavy metals in topsoil. The assessment on ecological risk of heavy metals was carried out using Hakanson's method, and the main resources of the heavy metals were analyzed as well. It was found that As, Cd and Co had the highest proportions exceeding Tianjin background value, which were 100%, 97.66% and 96.88%, respectively; the heavy-metal content increased to some extent comparing with that in 2004, and the pollutions of As and Cd were the worst, and other metals were at moderate pollution level or below. The ecological risks of heavy metals were different in topsoil with different land use types, the farmland soil in the southwest as well as soils adjacent to the industrial land were at relatively high potential ecological risk level, and the integrated ecological risk index reached up to 1 437.37. Analysis of correlation and principal component showed that traffic and transportation as well as agricultural activities might be the main resources of heavy metals in the area, besides, the industrial activities in the region might also affect the accumulation of heavy metals.

SADA: Ecological Risk Based Decision Support System for Selective Remediation

Science.gov (United States)

Spatial Analysis and Decision Assistance (SADA) is freeware that implements terrestrial ecological risk assessment and yields a selective remediation design using its integral geographical information system, based on ecological and risk assessment inputs. Selective remediation ...

Ecological correlates of multiple sexual partnerships among adolescents and young adults in urban Cape Town: a cumulative risk factor approach.

Science.gov (United States)

Muchiri, Evans; Odimegwu, Clifford; Banda, Pamela; Ntoimo, Lorreta; Adedini, Sunday

2017-07-01

Studies in South Africa have reported unsafe levels of risky sexual behvaiours among adolescents and young adults, with the country reporting the highest burden of HIV/AIDS globally, as well as a high rate of teenage pregnancy. While determinants of risky sexual behaviours have been investigated for factors occurring at the individual and household levels, not fully explored in the literature is the effect of community level factors. Furthermore, it is unclear whether risk factors occurring within the ecology of adolescents and young adults act cumulatively to influence their sexual practices. This article aims to address this knowledge gap using a case study of the Cape Area Panel Study of adolescents and young adults in urban Cape Town, South Africa. The ecological framework was adopted to guide the selection of risk factors at the individual, household, and community levels. Multivariate linear discriminant function analyses were used to select significant risk factors for multiple sexual partnerships and used to produce risk indices for the respondents. The cumulative risk approach was applied to test whether significant risk factors acted cumulatively. Findings point to the importance of ecological factors in influencing outcomes of multiple sexual partnerships among respondents and further demonstrate that ecological risk factors may act cumulatively. These findings are important for South Africa that is grappling with teenage pregnancy and disproportionate HIV epidemic among the youth.

Screening for substance abuse risk in cancer patients using the Opioid Risk Tool and urine drug screen.

Science.gov (United States)

Barclay, Joshua S; Owens, Justine E; Blackhall, Leslie J

2014-07-01

The use of opioids for management of cancer-related pain has increased significantly and has been associated with a substantial rise in rates of substance abuse and diversion. There is a paucity of data not only on the prevalence of substance abuse in cancer patients, but also for issues of drug use and diversion in family caregivers. This study aimed to evaluate the frequency of risk factors for substance abuse and diversion, and abnormal urine drug screens in cancer patients receiving palliative care. A retrospective chart review was performed for patients with cancer who were seen in the University of Virginia Palliative Care Clinic during the month of September 2012. We evaluated Opioid Risk Tool variables and total scores, insurance status, and urine drug screen results. Of the 114 cancer patients seen in September 2012, the mean Opioid Risk Tool score was 3.79, with 43% of patients defined as medium to high risk. Age (16-45 years old, 23%) and a personal history of alcohol (23%) or illicit drugs (21%) were the most common risk factors identified. We obtained a urine drug screen on 40% of patients, noting abnormal findings in 45.65%. Opioids are an effective treatment for cancer-related pain, yet substantial risk for substance abuse exits in the cancer population. Screening tools, such as the Opioid Risk Tool, should be used as part of a complete patient assessment to balance risk with appropriate relief of suffering.

Screening for nutritional risk in hospitalized children: comparison of two instruments

Directory of Open Access Journals (Sweden)

Dwi Novianti

2017-06-01

Full Text Available Background Malnutrition in hospitalized children has negative impact on morbidity, mortality, length of stay, and health-care cost. A simple screening tool is needed to detect hospital malnutrition risk in children. Objective To compare the level of agreement of the Screening Tool for Malnutrition in Pediatrics (STAMP and Pediatric Nutritional Risk Score (PNRS with anthropometric measurements, as screening tools for hospital malnutrition in children. Methods A cross-sectional study was conducted from February to July 2014 in the Pediatric and Surgery Wards at H. Adam Malik Hospital, Medan, North Sumatera. Inclusion criteria were children aged 2 to 18 years who were hospitalized for more than 72 hours. Subjects were screened using STAMP and PNRS, and underwent anthropometric measurement on admission. The weight measurements were repeated on the 3rd and 7th days, and just before discharge. The STAMP and PNRS results were compared in terms of level of agreement with anthropometric measurements. Data were analyzed by Kappa value and Spearman’s correlation test. Results A total of 127 children were screened with both instruments. The PNRS had slight agreement with hospital malnutrition prevalence (κ=0.175; P=0.028, while STAMP had not  (κ=0.080; P=0.193. Both screening tools had weak positive correlations with length of stay, but the correlation was stronger for PNRS than for STAMP (r=0.218; P=0.014 vs. r=0.188; P=0.034, respectively. The prevalence of hospital malnutrition was 40.9%.  Conclusions The PNRS screening tool has slight agreement with anthropometric measurement for identifying hospital malnutrition risk in children.

Reading curriculum-based measurement: screening Portuguese students at risk for dyslexia

OpenAIRE

Vaz, Paula Marisa Fortunato; Martins, Ana Paula Loução

2016-01-01

This poster presentation will present results from a study developed within the rst level of support, primary prevention, which was focused on identifying and preventing academic problems from occurring in those students enrolled in a school setting. How progress measurement was used in reading comprehension as a universal school screening system for third-grade Portuguese students will be analyzed. Results for level and growth in both groups of students at risk and not at risk and the risk ...

New information on high risk breast screening

International Nuclear Information System (INIS)

Riedl, C.C.; Ponhold, L.; Gruber, R.; Pinker, K.; Helbich, T.H.

2010-01-01

Women with an elevated risk for breast cancer require intensified screening beginning at an early age. Such high risk screening differs considerably from screening in the general population. After an expert has evaluated the exact risk a breast MRI examination should be offered at least once a year and beginning latest at the age of 30 depending on the patients risk category. Complementary mammograms should not be performed before the age of 35. An additional ultrasound examination is no longer recommended. To ensure a high sensitivity and specificity high risk screening should be performed only at a nationally or regionally approved and audited service. Adequate knowledge about the phenotypical characteristics of familial breast cancer is essential. Besides the common malignant phenotypes, benign morphologies (round or oval shape and smooth margins) as well as a low prevalence of calcifications have been described. Using MRI benign contrast media kinetics as well as non-solid lesions with focal, regional and segmental enhancement can often be visualized. (orig.) [de

Polycyclic aromatic hydrocarbons associated with road deposited solid and their ecological risk: Implications for road stormwater reuse

International Nuclear Information System (INIS)

Liu, Liang; Liu, An; Li, Yang; Zhang, Lixun; Zhang, Guijuan; Guan, Yuntao

2016-01-01

Reusing stormwater is becoming popular worldwide. However, urban road stormwater commonly contains toxic pollutants, such as polycyclic aromatic hydrocarbons (PAHs), which could undermine reuse safety. This study investigated pollution level of PAHs and their composition build-up on urban roads in a typical megacity in South China. The potential ecological risk posed by PAHs associated with road deposited solid (RDS) was also assessed. Results showed that ecological risk levels varied based on different land use types, which could be significantly influenced by the composition of PAHs and characteristics of RDS. A higher percentage of high-ring PAHs, such as more than four rings, could pose higher ecological risk and are more likely to undermine stormwater reuse safety. Additionally, the degree of traffic congestion rather than traffic volume was found to exert a more significant influence on the generation of high-ring PAH generation. Therefore, stormwater from more congested roads might need proper treatment (particularly for removing high-ring PAHs) before reuse or could be suitable for purposes requiring low-water-quality. The findings of this study are expected to contribute to adequate stormwater reuse strategy development and to enhance the safety of urban road stormwater reuse. - Highlights: • PAHs build-up on road surfaces varies with traffic and land use conditions. • RDS characteristics and PAH composition were considered in ecological risk assessment. • ΣPAH concentration attached to RDS cannot represent their overall ecological risk. • Higher percentage of 5–6 rings PAHs can pose higher ecological risk. • TC exerts more important influences on 5–6 rings PAHs build-up compared with TV.

Polycyclic aromatic hydrocarbons associated with road deposited solid and their ecological risk: Implications for road stormwater reuse

Energy Technology Data Exchange (ETDEWEB)

Liu, Liang [Graduate school at Shenzhen, Tsinghua University, Shenzhen 518055 (China); Liu, An [College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen 518060 (China); Li, Yang; Zhang, Lixun; Zhang, Guijuan [Graduate school at Shenzhen, Tsinghua University, Shenzhen 518055 (China); State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (MARC), Tsinghua University, Shenzhen 518055, Guangdong (China); Guan, Yuntao, E-mail: guanyt@tsinghua.edu.cn [Graduate school at Shenzhen, Tsinghua University, Shenzhen 518055 (China); State Environmental Protection Key Laboratory of Microorganism Application and Risk Control (MARC), Tsinghua University, Shenzhen 518055, Guangdong (China)

2016-09-01

Reusing stormwater is becoming popular worldwide. However, urban road stormwater commonly contains toxic pollutants, such as polycyclic aromatic hydrocarbons (PAHs), which could undermine reuse safety. This study investigated pollution level of PAHs and their composition build-up on urban roads in a typical megacity in South China. The potential ecological risk posed by PAHs associated with road deposited solid (RDS) was also assessed. Results showed that ecological risk levels varied based on different land use types, which could be significantly influenced by the composition of PAHs and characteristics of RDS. A higher percentage of high-ring PAHs, such as more than four rings, could pose higher ecological risk and are more likely to undermine stormwater reuse safety. Additionally, the degree of traffic congestion rather than traffic volume was found to exert a more significant influence on the generation of high-ring PAH generation. Therefore, stormwater from more congested roads might need proper treatment (particularly for removing high-ring PAHs) before reuse or could be suitable for purposes requiring low-water-quality. The findings of this study are expected to contribute to adequate stormwater reuse strategy development and to enhance the safety of urban road stormwater reuse. - Highlights: • PAHs build-up on road surfaces varies with traffic and land use conditions. • RDS characteristics and PAH composition were considered in ecological risk assessment. • ΣPAH concentration attached to RDS cannot represent their overall ecological risk. • Higher percentage of 5–6 rings PAHs can pose higher ecological risk. • TC exerts more important influences on 5–6 rings PAHs build-up compared with TV.

A Framework for Linking Population Model Development with Ecological Risk Assessment Objectives.

Science.gov (United States)

The value of models that link organism‐level impacts to the responses of a population in ecological risk assessments (ERAs) has been demonstrated extensively over the past few decades. There is little debate about the utility of these models to translate multiple organism&#...

Ecological risk assessment of agricultural soils for the definition of soil screening values: A comparison between substance-based and matrix-based approaches.

Science.gov (United States)

Pivato, Alberto; Lavagnolo, Maria Cristina; Manachini, Barbara; Vanin, Stefano; Raga, Roberto; Beggio, Giovanni

2017-04-01

The Italian legislation on contaminated soils does not include the Ecological Risk Assessment (ERA) and this deficiency has important consequences for the sustainable management of agricultural soils. The present research compares the results of two ERA procedures applied to agriculture (i) one based on the "substance-based" approach and (ii) a second based on the "matrix-based" approach. In the former the soil screening values (SVs) for individual substances were derived according to institutional foreign guidelines. In the latter, the SVs characterizing the whole-matrix were derived originally by the authors by means of experimental activity. The results indicate that the "matrix-based" approach can be efficiently implemented in the Italian legislation for the ERA of agricultural soils. This method, if compared to the institutionalized "substance based" approach is (i) comparable in economic terms and in testing time, (ii) is site specific and assesses the real effect of the investigated soil on a battery of bioassays, (iii) accounts for phenomena that may radically modify the exposure of the organisms to the totality of contaminants and (iv) can be considered sufficiently conservative.

[Ecological risk assessment of dam construction for terrestrial plant species in middle reach of Lancangjiang River, Southwest China].

Science.gov (United States)

Li, Xiao-Yan; Dong, Shi-Kui; Liu, Shi-Liang; Peng, Ming-Chun; Li, Jin-Peng; Zhao, Qing-He; Zhang, Zhao-Ling

2012-08-01

Taking the surrounding areas of Xiaowan Reservoir in the middle reach of Lancangjiang River as study area, and based on the vegetation investigation at three sites including electricity transmission area (site 1), electricity-transfer substation and roadsides to the substation (site 2), and emigration area (site 3) in 1997 (before dam construction), another investigation was conducted on the vegetation composition, plant coverage, and dominant species at the same sites in 2010 (after dam construction), aimed to evaluate the ecological risk of the dam construction for the terrestrial plant species in middle reach of Lancangjiang River. There was an obvious difference in the summed dominance ratio of dominant species at the three sites before and after the dam construction. According the types of species (dominant and non-dominant species) and the changes of plant dominance, the ecological risk (ER) for the plant species was categorized into 0 to IV, i.e., no or extremely low ecological risk (0), low ecological risk (I), medium ecological risk (II), high ecological risk (III), and extremely high ecological risk (IV). As affected by the dam construction, the majority of the species were at ER III, and a few species were at ER IV. The percentage of the plant species at ER III and ER IV at site 3 was higher than that at sites 1 and 2. The decrease or loss of native plants and the increase of alien or invasive plants were the major ecological risks caused by the dam construction. Effective protection strategies should be adopted to mitigate the ecological risk of the dam construction for the terrestrial plants at species level.

Risks of Lung Cancer Screening

Science.gov (United States)

... in women. Different factors increase or decrease the risk of lung cancer. Anything that increases your chance ... been studied to see if they decrease the risk of dying from lung cancer. The following screening ...

Newborn hearing screening programme in Belgium: a consensus recommendation on risk factors.

Science.gov (United States)

Vos, Bénédicte; Senterre, Christelle; Lagasse, Raphaël; Levêque, Alain

2015-10-16

Understanding the risk factors for hearing loss is essential for designing the Belgian newborn hearing screening programme. Accordingly, they needed to be updated in accordance with current scientific knowledge. This study aimed to update the recommendations for the clinical management and follow-up of newborns with neonatal risk factors of hearing loss for the newborn screening programme in Belgium. A literature review was performed, and the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system assessment method was used to determine the level of evidence quality and strength of the recommendation for each risk factor. The state of scientific knowledge, levels of evidence quality, and graded recommendations were subsequently assessed using a three-round Delphi consensus process (two online questionnaires and one face-to-face meeting). Congenital infections (i.e., cytomegalovirus, toxoplasmosis, and syphilis), a family history of hearing loss, consanguinity in (grand)parents, malformation syndromes, and foetal alcohol syndrome presented a 'high' level of evidence quality as neonatal risk factors for hearing loss. Because of the sensitivity of auditory function to bilirubin toxicity, hyperbilirubinaemia was assessed at a 'moderate' level of evidence quality. In contrast, a very low birth weight, low Apgar score, and hospitalisation in the neonatal intensive care unit ranged from 'very low' to 'low' levels, and ototoxic drugs were evidenced as 'very low'. Possible explanations for these 'very low' and 'low' levels include the improved management of these health conditions or treatments, and methodological weaknesses such as confounding effects, which make it difficult to conclude on individual risk factors. In the recommendation statements, the experts emphasised avoiding unidentified neonatal hearing loss and opted to include risk factors for hearing loss even in cases with weak evidence. The panel also highlighted the cumulative effect

An assessment of ecological and case-control methods for estimating lung cancer risk due to indoor radon

International Nuclear Information System (INIS)

Stidley, C.A.; Samet, J.M.

1992-01-01

Studies of underground miners indicate that indoor radon is an important cause of lung cancer. This finding has raised concern that exposure to radon also causes lung cancer in the general population. Epidemiological studies, including both case-control and ecological approaches, have directly addressed the risks of indoor residential radon; many more case-control studies are in progress. Ecological studies that associate lung-cancer rates with typical indoor radon levels in various geographic areas have not consistently shown positive associations. The results of purportedly negative ecological studies have been used as a basis for questioning the hazards of indoor radon exposure. Because of potentially serious methodologic flaws for testing hypotheses, we examined the ecological method as a tool for assessing lung-cancer risk from indoor radon exposure. We developed a simulation approach that utilizes the Environmental Protection Agency (EPA) radon survey data to assign exposures to individuals within counties. Using the computer-generated data, we compared risk estimates obtained by ecological regression methods with those obtained from other regression methods and with the open-quotes trueclose quotes risks used to generate the data. For many of these simulations, the ecological models, while fitting the summary data well, gave risk estimates that differed considerably from the true risks. For some models, the risk estimates were negatively correlated with exposure, although the assumed relationship was positive. Attempts to improve the ecological models by adding smoking variables, including interaction terms, did not always improve the estimates of risk, which are easily affected by model misspecification. Because exposure situations used in the simulations are realistic, our results show that ecological methods may not accurately estimate the lung-cancer risk associated with indoor radon exposure

Benefit-risk evaluation of mammographic mass screening

International Nuclear Information System (INIS)

Sato, Nobuo; Ogura, Toshihiro

1990-01-01

This study evaluated the benefit-risk balance of mammography in mass screening by using survival rates from 3000 breast cancer patients at the Japanese Foundation for Cancer Research Institute Hospital. Because the number of participants in mammographic mass screening was small, asymptomatic patients with pathologically proven early breast cancer were categorized as the screenee group. Symptomatic patients were categorized as the patient group. Survival rates were compared in both the screenee and the patient groups. Based on the difference in areas of survival curves between screenees and patients, the ratio of person-year gain (PYG) to person-year lost (PYL) was obtained. The ratio of PYG to PYL was multiplied by the detection rate resulting from a particular screening program to obtain the benefit/risk ratio. The detection rate of nonpalpable breast cancer was 15 times higher in the screenee group than the patient group. Breast cancer was detected in 7 (0.85%) of 824 patients in the screenee group. Even when mammographic mass screening was started at the age of 30, the benefit of mammography was far superior to the risk. The number of participants in mass screening stratified by age may be required for the conclusion of the benefit-risk balance of mammography in mass screening. (N.K.)

Suicide Risk Screening Tools and the Youth Population.

Science.gov (United States)

Patterson, Sharon

2016-08-01

The use of suicide risk screening tools is a critical component of a comprehensive approach to suicide risk assessment. Since nurses frequently spend more time with patients than any other healthcare professional, they are in key positions to detect and prevent suicidal behavior in youth. To inform nurses about suicide risk screening tools for the youth population. Suicide risk screening tools are research-based standardized instruments that are used to identify people who may be at risk for suicide. A literature search was performed using the Athabasca University Library Resource, the databases of the Cumulative Index to Nursing and Allied Health Literature, ScienceDirect, and Google Scholar. Nurses are cautioned to utilize suicide risk screening tools as only part of the suicide risk assessment in youth populations and avoid the danger of relying on tools that may result in a blind application of evidence to the detriment of clinical experience and judgement. © 2016 Wiley Periodicals, Inc.

Geographic variation and effect of area-level poverty rate on colorectal cancer screening.

Science.gov (United States)

Lian, Min; Schootman, Mario; Yun, Shumei

2008-10-16

With a secular trend of increasing colorectal cancer (CRC) screening, concerns about disparities in CRC screening also have been rising. It is unclear if CRC screening varies geographically, if area-level poverty rate affects CRC screening, and if individual-level characteristics mediate the area-level effects on CRC screening. Using 2006 Missouri Behavioral Risk Factor Surveillance System (BRFSS) data, a multilevel study was conducted to examine geographic variation and the effect of area-level poverty rate on CRC screening use among persons age 50 or older. Individuals were nested within ZIP codes (ZIP5 areas), which in turn, were nested within aggregations of ZIP codes (ZIP3 areas). Six groups of individual-level covariates were considered as potential mediators. An estimated 51.8% of Missourians aged 50 or older adhered to CRC screening recommendations. Nearly 15% of the total variation in CRC screening lay between ZIP5 areas. Persons residing in ZIP5 areas with > or = 10% of poverty rate had lower odds of CRC screening use than those residing in ZIP5 areas with poverty rate (unadjusted odds ratio [OR], 0.69; 95% confidence interval [95% CI], 0.58-0.81; adjusted OR, 0.81; 95% CI, 0.67-0.98). Persons who resided in ZIP3 areas with > or = 20% poverty rate also had lower odds of following CRC screening guidelines than those residing in ZIP3 areas with poverty rate (unadjusted OR, 0.66; 95% CI, 0.52-0.83; adjusted OR, 0.64; 95% CI, 0.50-0.83). Obesity, history of depression/anxiety and access to care were associated with CRC screening, but did not mediate the effect of area-level poverty on CRC screening. Large geographic variation of CRC screening exists in Missouri. Area-level poverty rate, independent of individual-level characteristics, is a significant predictor of CRC screening, but it only explains a small portion of the geographic heterogeneity of CRC screening. Individual-level factors we examined do not mediate the effect of the area-level poverty rate on

Novel two-tiered approach of ecological risk assessment for pesticide mixtures based on joint effects.

Science.gov (United States)

Tian, Dayong; Mao, Haichen; Lv, Huichao; Zheng, Yong; Peng, Conghu; Hou, Shaogang

2018-02-01

Ecological risk assessments for mixtures have attracted considerable attention. In this study, 38 pesticides in the real environment were taken as objects and their toxicities to different organisms from three trophic levels were employed to assess the ecological risk of the mixture. The first tier assessment was based on the CA effect and the obtained sum of risk quotients (SRQ species-CA ) were 3.06-9.22. The second tier assessment was based on non-CA effects and the calculated SRQ species-TU are 5.37-9.29 using joint effects (TU sum ) as modified coefficients, which is higher than SRQ species-CA and indicates that ignoring joint effects might run the risk of underestimating the actual impact of pesticide mixtures. Due to the influences of synergistic and antagonistic effects, risk contribution of components to mixture risks based on non-CA effects are different from those based on the CA effect. Moreover, it was found that the top 8 dominating components explained 95.5%-99.8% of mixture risks in this study. The dominating components are similar in the two tiers for a given species. Accordingly, a novel two-tiered approach was proposed to assess the ecological risks of mixtures based on joint effects. This study provides new insights for ecological risk assessments with the consideration of joint effects of components in the pesticide mixtures. Copyright © 2017 Elsevier Ltd. All rights reserved.

Toward refined environmental scenarios for ecological risk assessment of down-the-drain chemicals in freshwater environments.

Science.gov (United States)

Franco, Antonio; Price, Oliver R; Marshall, Stuart; Jolliet, Olivier; Van den Brink, Paul J; Rico, Andreu; Focks, Andreas; De Laender, Frederik; Ashauer, Roman

2017-03-01

Current regulatory practice for chemical risk assessment suffers from the lack of realism in conventional frameworks. Despite significant advances in exposure and ecological effect modeling, the implementation of novel approaches as high-tier options for prospective regulatory risk assessment remains limited, particularly among general chemicals such as down-the-drain ingredients. While reviewing the current state of the art in environmental exposure and ecological effect modeling, we propose a scenario-based framework that enables a better integration of exposure and effect assessments in a tiered approach. Global- to catchment-scale spatially explicit exposure models can be used to identify areas of higher exposure and to generate ecologically relevant exposure information for input into effect models. Numerous examples of mechanistic ecological effect models demonstrate that it is technically feasible to extrapolate from individual-level effects to effects at higher levels of biological organization and from laboratory to environmental conditions. However, the data required to parameterize effect models that can embrace the complexity of ecosystems are large and require a targeted approach. Experimental efforts should, therefore, focus on vulnerable species and/or traits and ecological conditions of relevance. We outline key research needs to address the challenges that currently hinder the practical application of advanced model-based approaches to risk assessment of down-the-drain chemicals. Integr Environ Assess Manag 2017;13:233-248. © 2016 SETAC. © 2016 SETAC.

An approach for balancing health and ecological risks at hazardous waste sites

International Nuclear Information System (INIS)

Suter, G.W. II; Hull, R.N.; Stack, M.; Cornaby, B.W.; Hadden, C.T.; Zafran, F.A.

1995-01-01

Human health and ecological risks must be balanced at hazardous waste sites in order to ensure that remedial actions prevent unacceptable risks of either type. Actions that are designed to protect humans may fail to protect nonhuman populations and ecosystems or may damage ecosystems. However, there is no common scale of health and ecological risk that would allow comparisons to be performed. This paper presents an approach to addressing this problem based on classifying all risks (i.e., health and ecological risks due contaminants and remediation) as insignificant (de minimis), highly significant (de manifestis), or intermediate. For health risks the classification is based on standard criteria. However, in the absence of national guidance concerning the acceptability of ecological risks, new ecological criteria are proposed based on an analysis of regulatory precedents. Matrices and flow charts are presented to guide the use of these risk categories in remedial decision making. The assessment of mercury contamination of the East Fork Poplar Creek is presented as an example of the implementation of the approach. 15 refs., 3 figs., 3 tabs

[Screening for atherosclerosis to prevent cardiovascular risk : a pro-contra debate].

Science.gov (United States)

Nanchen, David; Genest, Jacques

2018-02-28

Detecting atherosclerosis using imaging techniques is the subject of intense debate in the scientific community. Among the arguments in favor of screening, a better identification or better stratification of cardiovascular risk is mentioned, compared to cardiovascular risk scores based solely on traditional risk factors, such as blood pressure or cholesterol levels. Imaging techniques are also used to monitor the progression of atherosclerosis among patients using lipid-lowering or antihypertensive drugs in primary prevention. However, several experts in recent years have challenged the clinical utility of these imaging techniques in asymptomatic adults. This article proposes a debate « for or against » to describe the main arguments for or against the use of imaging for screening for atherosclerosis.

Risk Profiling May Improve Lung Cancer Screening

Science.gov (United States)

A new modeling study suggests that individualized, risk-based selection of ever-smokers for lung cancer screening may prevent more lung cancer deaths and improve the effectiveness and efficiency of screening compared with current screening recommendations

Benefit and risk in breast screening

International Nuclear Information System (INIS)

Law, J.; Faulkner, K.; Neilson, F.

2001-01-01

Justification of breast screening in radiation protection terms both for the screened population and on an individual basis is necessary. In this paper the number of cancers detected, and the number of cancers potentially induced by radiation in the UK National Health Service Breast Screening Programme (NHS BSP) are compared. Detection rates reported up to 1998 are used, with x-ray doses for 1997 and 1998 and breast cancer induction risk factors, stratified by age, recommended by the National Radiological Protection Board in 1994. Cancers detected exceed those potentially induced at all ages from 50-64. The relationship between these cancer numbers and the associated benefit and risk, in terms of breast cancer deaths avoided and induced, is then investigated. Improved values of the Nottingham Prognostic Indicator (NPI) attributed to screening provide one means of doing this. Using this strict criterion the breast-screening programme is also justified in radiation protection terms. (author)

Sustainable and safe design of footwear integrating ecological footprint and risk criteria

International Nuclear Information System (INIS)

Herva, Marta; Alvarez, Antonio; Roca, Enrique

2011-01-01

Highlights: → The ecological footprint (EF) is a suitable screening indicator to assist the assessment of the sustainability of an ecodesign proposal. → The EF does not consider the risk derived from hazardous substances in its evaluation. → Environmental risk assessment (ERA) successfully complemented the evaluation of the EF providing safety criteria. → Options that exceeded the safety limits for Hazard Quotient and Cancer Risk where discarded, thus guaranteeing the protection of children. → Trade-offs among criteria could be established by the application of fuzzy logic techniques to derive an ecodesign index. - Abstract: The ecodesign of a product implies that different potential environmental impacts of diverse nature must be taken into account considering its whole life cycle, apart from the general design criteria (i.e. technical, functional, ergonomic, aesthetic or economic). In this sense, a sustainability assessment methodology, ecological footprint (EF), and environmental risk assessment (ERA), were combined for the first time to derive complementary criteria for the ecodesign of footwear. Four models of children's shoes were analyzed and compared. The synthetic shoes obtained a smaller EF (6.5 gm 2 ) when compared to the leather shoes (11.1 gm 2 ). However, high concentrations of hazardous substances were detected in the former, even making the Hazard Quotient (HQ) and the Cancer Risk (CR) exceed the recommended safety limits for one of the synthetic models analyzed. Risk criteria were prioritized in this case and, consequently, the design proposal was discarded. For the other cases, the perspective provided by the indicators of different nature was balanced to accomplish a fairest evaluation. The selection of fibers produced under sustainable criteria and the reduction of the materials consumption was recommended, since the area requirements would be minimized and the absence of hazardous compounds would ensure safety conditions during the

Sustainable and safe design of footwear integrating ecological footprint and risk criteria

Energy Technology Data Exchange (ETDEWEB)

Herva, Marta [Sustainable Processes and Products Engineering Group, Department of Chemical Engineering, University of Santiago de Compostela, Campus Vida, 15705 Santiago de Compostela (Spain); Alvarez, Antonio [Industrias de Diseno Textil, S.A., Edificio Inditex, Av. de la Diputacion s/n, Poligono de Sabon, 15142 Arteixo - A Coruna (Spain); Roca, Enrique, E-mail: enrique.roca@usc.es [Sustainable Processes and Products Engineering Group, Department of Chemical Engineering, University of Santiago de Compostela, Campus Vida, 15705 Santiago de Compostela (Spain)

2011-09-15

Highlights: {yields} The ecological footprint (EF) is a suitable screening indicator to assist the assessment of the sustainability of an ecodesign proposal. {yields} The EF does not consider the risk derived from hazardous substances in its evaluation. {yields} Environmental risk assessment (ERA) successfully complemented the evaluation of the EF providing safety criteria. {yields} Options that exceeded the safety limits for Hazard Quotient and Cancer Risk where discarded, thus guaranteeing the protection of children. {yields} Trade-offs among criteria could be established by the application of fuzzy logic techniques to derive an ecodesign index. - Abstract: The ecodesign of a product implies that different potential environmental impacts of diverse nature must be taken into account considering its whole life cycle, apart from the general design criteria (i.e. technical, functional, ergonomic, aesthetic or economic). In this sense, a sustainability assessment methodology, ecological footprint (EF), and environmental risk assessment (ERA), were combined for the first time to derive complementary criteria for the ecodesign of footwear. Four models of children's shoes were analyzed and compared. The synthetic shoes obtained a smaller EF (6.5 gm{sup 2}) when compared to the leather shoes (11.1 gm{sup 2}). However, high concentrations of hazardous substances were detected in the former, even making the Hazard Quotient (HQ) and the Cancer Risk (CR) exceed the recommended safety limits for one of the synthetic models analyzed. Risk criteria were prioritized in this case and, consequently, the design proposal was discarded. For the other cases, the perspective provided by the indicators of different nature was balanced to accomplish a fairest evaluation. The selection of fibers produced under sustainable criteria and the reduction of the materials consumption was recommended, since the area requirements would be minimized and the absence of hazardous compounds would

Screening situations for risk of ethical conflicts: a pilot study.

Science.gov (United States)

Pavlish, Carol L; Hellyer, Joan Henriksen; Brown-Saltzman, Katherine; Miers, Anne G; Squire, Karina

2015-05-01

Ethical conflicts, often leading to poor teamwork and moral distress, are very challenging to patients, patients' families, and health care providers. A proactive approach to ethical conflicts may improve patient care outcomes. To examine acceptability and feasibility of an ethics screening and early intervention tool for use by nurses caring for critically ill patients. Twenty-eight nurses in 2 medical centers applied the ethics screening tool to 55 patient situations. Nurses assessed situations for risk factors and early indicators of ethical conflicts and analyzed level of risk. At study completion, nurses participated in focus group discussions about the tool's benefits and challenges. Frequency counts were performed on risk factors and early indicators of ethical conflicts. Content analysis was used on written explanations regarding high-, medium-, and low-risk situations and on focus group data. Older patients with multiple comorbid conditions and aggressive treatments were frequently assessed to be at risk for ethical conflicts. Nurses who witnessed patients' suffering and deterioration were likely to initiate the screening process. The most prominent family risk factors included unrealistic expectations and adamancy about treatment. The most prominent early indicators were signs of patients' suffering, unrealistic expectations, and providers' own moral distress. High-risk situations averaged a greater number of risk factors and early indicators than did medium- and low-risk situations. Certain risk factors featured prominently in high-risk situations. A phenomenon of shared suffering emerged from the study and signifies the importance of relational strategies such as routine family conferences and ethics consultation. ©2015 American Association of Critical-Care Nurses.

Determining Childhood Blood Lead Level Screening Compliance Among Physicians.

Science.gov (United States)

Haboush-Deloye, Amanda; Marquez, Erika R; Gerstenberger, Shawn L

2017-08-01

Childhood Lead Poisoning Prevention Programs throughout the U.S. have addressed childhood lead poisoning by implementing primary and secondary prevention efforts. While many programs have helped increase screening rates, in some states children under the age of six still have not been tested for lead. This study aims to identify the barriers to childhood blood lead testing and develop a strategy to increase the number of children tested. Clark County physicians who work with children six and under were surveyed about blood lead level (BLL) testing practices, particularly, adherence to Centers for Disease Control and Prevention (CDC) guidelines, and parental compliance with orders to have their children tested to determine their blood lead levels. In addition, select in-person interviews were conducted with physicians who reported high parental compliance to identify best practices and barriers. Of the 77 physicians that provided data, 48% indicated they did not follow CDC guideline compared to 52% who follow guidelines. 18 of the 30 (or 60%) physicians reported more than 80% of parents complied with doctor recommended BLL testing. Twelve physicians identified cost, lack of insurance, and absence of symptomology as persistent barriers to lead screening. This study identified barriers to childhood lead screening including inadequate parental adherence to physician-ordered screenings and physician non-compliance with screening recommendations are two primary contributors. Addressing these issues could increase screening in children and reduce the risk of lead poisoning.

Chemical Risk Assessment Screening Tool of a Global Chemical Company

Directory of Open Access Journals (Sweden)

Evelyn Tjoe-Nij

2018-03-01

Full Text Available Background: This paper describes a simple-to-use and reliable screening tool called Critical Task Exposure Screening (CTES, developed by a chemical company. The tool assesses if the exposure to a chemical for a task is likely to be within acceptable levels. Methods: CTES is a Microsoft Excel tool, where the inhalation risk score is calculated by relating the exposure estimate to the corresponding occupational exposure limit (OEL or occupational exposure band (OEB. The inhalation exposure is estimated for tasks by preassigned ART1.5 activity classes and modifying factors. Results: CTES requires few inputs. The toxicological data, including OELs, OEBs, and vapor pressure are read from a database. Once the substance is selected, the user specifies its concentration and then chooses the task description and its duration. CTES has three outputs that may trigger follow-up: (1 inhalation risk score; (2 identification of the skin hazard with the skin warnings for local and systemic adverse effects; and (3 status for carcinogenic, mutagenic, or reprotoxic effects. Conclusion: The tool provides an effective way to rapidly screen low-concern tasks, and quickly identifies certain tasks involving substances that will need further review with, nevertheless, the appropriate conservatism. This tool shows that the higher-tier ART1.5 inhalation exposure assessment model can be included effectively in a screening tool. After 2 years of worldwide extensive use within the company, CTES is well perceived by the users, including the shop floor management, and it fulfills its target of screening tool. Keywords: occupational exposure, risk assessment, risk management

Chemical Risk Assessment Screening Tool of a Global Chemical Company

OpenAIRE

Evelyn Tjoe-Nij; Christophe Rochin; Nathalie Berne; Alessandro Sassi; Antoine Leplay

2018-01-01

Background: This paper describes a simple-to-use and reliable screening tool called Critical Task Exposure Screening (CTES), developed by a chemical company. The tool assesses if the exposure to a chemical for a task is likely to be within acceptable levels. Methods: CTES is a Microsoft Excel tool, where the inhalation risk score is calculated by relating the exposure estimate to the corresponding occupational exposure limit (OEL) or occupational exposure band (OEB). The inhalation exposure i...

Application of ecological risk assessment principles to evaluation of oil spill impacts

International Nuclear Information System (INIS)

Brannon, E.L.; Neff, J.M.; Pearson, W.H.; Stubblefield, W.A.; Maki, A.W.

1995-01-01

Ecological risk assessments are often used prospectively to predict the consequences of human activities on the environment. Laboratory and field studies were conducted to evaluate the ecological impacts to commercial fishery resources resulting from the Exxon Valdez oil spill. Using the ecorisk paradigm, each of the studies correlated concentrations of petroleum hydrocarbons in different environmental compartments with observed biological effects in local populations of herring and pink salmon. Hydrocarbon concentrations in the water column of the Sound were elevated for a short time after the spill, but 99.7% of the samples remained below the Alaska water quality standard and returned to background levels within a few months. PAH concentrations in sediments and eggs correlated with a very low degree of injury to early life stages of herring and salmon. Overall, effects of the spill on populations of herring and pink salmon were minimal and post-spill harvests of the year classes at greater risk of spill injury in the two years following the spill were at or near record levels. The program underscores the utility and strength of the risk assessment paradigm to identify contaminant related injury while considering effects attributable to natural ecosystem variability

Tailoring Breast Cancer Screening Intervals by Breast Density and Risk for Women Aged 50 Years or Older: Collaborative Modeling of Screening Outcomes.

Science.gov (United States)

Trentham-Dietz, Amy; Kerlikowske, Karla; Stout, Natasha K; Miglioretti, Diana L; Schechter, Clyde B; Ergun, Mehmet Ali; van den Broek, Jeroen J; Alagoz, Oguzhan; Sprague, Brian L; van Ravesteyn, Nicolien T; Near, Aimee M; Gangnon, Ronald E; Hampton, John M; Chandler, Young; de Koning, Harry J; Mandelblatt, Jeanne S; Tosteson, Anna N A

2016-11-15

Biennial screening is generally recommended for average-risk women aged 50 to 74 years, but tailored screening may provide greater benefits. To estimate outcomes for various screening intervals after age 50 years based on breast density and risk for breast cancer. Collaborative simulation modeling using national incidence, breast density, and screening performance data. United States. Women aged 50 years or older with various combinations of breast density and relative risk (RR) of 1.0, 1.3, 2.0, or 4.0. Annual, biennial, or triennial digital mammography screening from ages 50 to 74 years (vs. no screening) and ages 65 to 74 years (vs. biennial digital mammography from ages 50 to 64 years). Lifetime breast cancer deaths, life expectancy and quality-adjusted life-years (QALYs), false-positive mammograms, benign biopsy results, overdiagnosis, cost-effectiveness, and ratio of false-positive results to breast cancer deaths averted. Screening benefits and overdiagnosis increase with breast density and RR. False-positive mammograms and benign results on biopsy decrease with increasing risk. Among women with fatty breasts or scattered fibroglandular density and an RR of 1.0 or 1.3, breast cancer deaths averted were similar for triennial versus biennial screening for both age groups (50 to 74 years, median of 3.4 to 5.1 vs. 4.1 to 6.5 deaths averted; 65 to 74 years, median of 1.5 to 2.1 vs. 1.8 to 2.6 deaths averted). Breast cancer deaths averted increased with annual versus biennial screening for women aged 50 to 74 years at all levels of breast density and an RR of 4.0, and those aged 65 to 74 years with heterogeneously or extremely dense breasts and an RR of 4.0. However, harms were almost 2-fold higher. Triennial screening for the average-risk subgroup and annual screening for the highest-risk subgroup cost less than $100 000 per QALY gained. Models did not consider women younger than 50 years, those with an RR less than 1, or other imaging methods. Average-risk women

Breast cancer screening in an era of personalized regimens: a conceptual model and National Cancer Institute initiative for risk-based and preference-based approaches at a population level.

Science.gov (United States)

Onega, Tracy; Beaber, Elisabeth F; Sprague, Brian L; Barlow, William E; Haas, Jennifer S; Tosteson, Anna N A; D Schnall, Mitchell; Armstrong, Katrina; Schapira, Marilyn M; Geller, Berta; Weaver, Donald L; Conant, Emily F

2014-10-01

Breast cancer screening holds a prominent place in public health, health care delivery, policy, and women's health care decisions. Several factors are driving shifts in how population-based breast cancer screening is approached, including advanced imaging technologies, health system performance measures, health care reform, concern for "overdiagnosis," and improved understanding of risk. Maximizing benefits while minimizing the harms of screening requires moving from a "1-size-fits-all" guideline paradigm to more personalized strategies. A refined conceptual model for breast cancer screening is needed to align women's risks and preferences with screening regimens. A conceptual model of personalized breast cancer screening is presented herein that emphasizes key domains and transitions throughout the screening process, as well as multilevel perspectives. The key domains of screening awareness, detection, diagnosis, and treatment and survivorship are conceptualized to function at the level of the patient, provider, facility, health care system, and population/policy arena. Personalized breast cancer screening can be assessed across these domains with both process and outcome measures. Identifying, evaluating, and monitoring process measures in screening is a focus of a National Cancer Institute initiative entitled PROSPR (Population-based Research Optimizing Screening through Personalized Regimens), which will provide generalizable evidence for a risk-based model of breast cancer screening, The model presented builds on prior breast cancer screening models and may serve to identify new measures to optimize benefits-to-harms tradeoffs in population-based screening, which is a timely goal in the era of health care reform. © 2014 American Cancer Society.

[Study on distribution characteristics and potential ecological risk of soil heavy metals in the Yellow River beach region in Kaifeng City].

Science.gov (United States)

Zhang, Peng-yan; Qin, Ming-zhou; Chen, Long; Hu, Chang-hui; Zhao, Ya-ping; Dong, Wei-jun

2013-09-01

The distributions, soil environment status and potential ecological risk of heavy metals were studied in beach soil of returning the cropland into Yellow River beach region in Kaifeng by the Nemerows and Håkansons methods. The results showed that (1) as Among the average contents of the five heavy metals Pb, Cr, Hg, As and Cd, the highest was the average content of Cr, and the lowest was the average content of Pb and Hg. In addition to Hg, the coefficients of variation of other heavy metals were relatively small, indicating that the content of heavy metals was quite different at different sites, and to some extent, relecting that Hg, As and Pb were the major elements polluting the soil, among which, Pb pollution was the pollution with universality. There was little difference in the contents of Cr and Cd from village to village the coefficient of variation was small, and the contents were below the national standard level. (2) There was significant difference in the spatial distribution of soil heavy metal elements in the upper, the middle and lower sections of the study area. The upper section was clean, the middle section was slightly polluted, and the lower section was enriched with pollutants. (3) The distribution of heavy metals in the beach region inside and outside the levees of Yellow River was closely related to the distribution of the residential regions. In the upper section of the beach region (southwest), the population was large and the contents of heavy metals were high. The contents of heavy metals were lower in the near river zone than outside the levees of Yellow River. And the heavy metal contents in the middle and lower section were higher than those outside the levees of Yellow River, while the lower section (northwest) showed a tendency of pollution enrichment. (4) In the view of the average individual potential ecological risk index of heavy metals (E(r)i), the potential ecological risk of Hg reached intense levels, and the potential

A quantitative screening-level approach to incorporate chemical exposure and risk into alternative assessment evaluations.

Science.gov (United States)

Arnold, Scott M; Greggs, Bill; Goyak, Katy O; Landenberger, Bryce D; Mason, Ann M; Howard, Brett; Zaleski, Rosemary T

2017-11-01

As the general public and retailers ask for disclosure of chemical ingredients in the marketplace, a number of hazard screening tools were developed to evaluate the so-called "greenness" of individual chemical ingredients and/or formulations. The majority of these tools focus only on hazard, often using chemical lists, ignoring the other part of the risk equation: exposure. Using a hazard-only focus can result in regrettable substitutions, changing 1 chemical ingredient for another that turns out to be more hazardous or shifts the toxicity burden to others. To minimize the incidents of regrettable substitutions, BizNGO describes "Common Principles" to frame a process for informed substitution. Two of these 6 principles are: "reduce hazard" and "minimize exposure." A number of frameworks have emerged to evaluate and assess alternatives. One framework developed by leading experts under the auspices of the US National Academy of Sciences recommended that hazard and exposure be specifically addressed in the same step when assessing candidate alternatives. For the alternative assessment community, this article serves as an informational resource for considering exposure in an alternatives assessment using elements of problem formulation; product identity, use, and composition; hazard analysis; exposure analysis; and risk characterization. These conceptual elements build on practices from government, academia, and industry and are exemplified through 2 hypothetical case studies demonstrating the questions asked and decisions faced in new product development. These 2 case studies-inhalation exposure to a generic paint product and environmental exposure to a shampoo rinsed down the drain-demonstrate the criteria, considerations, and methods required to combine exposure models addressing human health and environmental impacts to provide a screening level hazard and exposure (risk) analysis. This article informs practices for these elements within a comparative risk context

Pollution, ecological-health risks, and sources of heavy metals in soil of the northeastern Qinghai-Tibet Plateau.

Science.gov (United States)

Wu, Jun; Lu, Jian; Li, Leiming; Min, Xiuyun; Luo, Yongming

2018-06-01

The Qinghai-Tibet Plateau, especially the northeastern region, is not a pure land any more due to recently increasing anthropogenic activities. This study collected soil samples from 70 sites of the northeastern Qinghai-Tibet Plateau to evaluate pollution, ecological-health risks, and possible pollution sources of heavy metals. The concentrations of heavy metals in soil were relatively high. Values of geo-accumulation index exhibited that Hg pollution was the most serious meanwhile Hg possessed the strongest enrichment feature based on enrichment factor values. The modified degrees of contamination showed that about 54.3% and 17.1% of sampling sites were at moderate and high contamination degree while pollution load indexes illustrated that 72.9% and 27.1% of sampling sites possessed moderate and high contamination level, respectively. Ecological risk indexes of heavy metals in soil ranged from 234.6 to 3759.0, suggesting that most of sites were under considerable/very high risks. Cancer risks for adults and children were determined as high and high-very high levels while non-cancer risks for children were high although those for adults were low. Industrial source contributed to the main fraction of ecological and health risks. Summarily speaking, heavy metals in soil of the study area has caused significantly serious pollution and exerted high potential ecological and health risks, especially for children who are more susceptible to hurt from pollutants. Therefore, more efficient and strict pollution control and management in study area should be put out as soon as possible. Copyright © 2018 Elsevier Ltd. All rights reserved.

Ecological risk assessment of agricultural soils for the definition of soil screening values: A comparison between substance-based and matrix-based approaches

Directory of Open Access Journals (Sweden)

Alberto Pivato

2017-04-01

Full Text Available The Italian legislation on contaminated soils does not include the Ecological Risk Assessment (ERA and this deficiency has important consequences for the sustainable management of agricultural soils. The present research compares the results of two ERA procedures applied to agriculture (i one based on the “substance-based” approach and (ii a second based on the “matrix-based” approach. In the former the soil screening values (SVs for individual substances were derived according to institutional foreign guidelines. In the latter, the SVs characterizing the whole-matrix were derived originally by the authors by means of experimental activity.The results indicate that the “matrix-based” approach can be efficiently implemented in the Italian legislation for the ERA of agricultural soils. This method, if compared to the institutionalized “substance based” approach is (i comparable in economic terms and in testing time, (ii is site specific and assesses the real effect of the investigated soil on a battery of bioassays, (iii accounts for phenomena that may radically modify the exposure of the organisms to the totality of contaminants and (iv can be considered sufficiently conservative. Keyword: Environmental science

Developing predictive systems models to address complexity and relevance for ecological risk assessment.

Science.gov (United States)

Forbes, Valery E; Calow, Peter

2013-07-01

Ecological risk assessments (ERAs) are not used as well as they could be in risk management. Part of the problem is that they often lack ecological relevance; that is, they fail to grasp necessary ecological complexities. Adding realism and complexity can be difficult and costly. We argue that predictive systems models (PSMs) can provide a way of capturing complexity and ecological relevance cost-effectively. However, addressing complexity and ecological relevance is only part of the problem. Ecological risk assessments often fail to meet the needs of risk managers by not providing assessments that relate to protection goals and by expressing risk in ratios that cannot be weighed against the costs of interventions. Once more, PSMs can be designed to provide outputs in terms of value-relevant effects that are modulated against exposure and that can provide a better basis for decision making than arbitrary ratios or threshold values. Recent developments in the modeling and its potential for implementation by risk assessors and risk managers are beginning to demonstrate how PSMs can be practically applied in risk assessment and the advantages that doing so could have. Copyright © 2013 SETAC.

Measurement and Evaluation of Ecological Risk of Heavy Metals in Surface Sediments of Pars Special Economic Energy Zone

OpenAIRE

Arash Haghshenas; Masoud Hatami-manesh; Mohsen Mirzaei; MirMehrdad Mir Sanjari; Parisa Hossein Khezri

2017-01-01

Background: Today, heavy metals pollution in aquatic ecosystems is one of the most important global environmental problems. Because this metals have characteristics such as chemical stability, low degradability and bioaccumulation ability at different levels of the food chain cause the abundant ecological risks for organisms. Therefore, this study investigates the concentration of heavy metals (mercury, cadmium, lead, chromium, copper, nickel, zinc and iron) and ecological risk assessment of ...

Levels of organization in biology: on the nature and nomenclature of ecology's fourth level.

Science.gov (United States)

Lidicker, William Z

2008-02-01

Viewing the universe as being composed of hierarchically arranged systems is widely accepted as a useful model of reality. In ecology, three levels of organization are generally recognized: organisms, populations, and communities (biocoenoses). For half a century increasing numbers of ecologists have concluded that recognition of a fourth level would facilitate increased understanding of ecological phenomena. Sometimes the word "ecosystem" is used for this level, but this is arguably inappropriate. Since 1986, I and others have argued that the term "landscape" would be a suitable term for a level of organization defined as an ecological system containing more than one community type. However, "landscape" and "landscape level" continue to be used extensively by ecologists in the popular sense of a large expanse of space. I therefore now propose that the term "ecoscape" be used instead for this fourth level of organization. A clearly defined fourth level for ecology would focus attention on the emergent properties of this level, and maintain the spatial and temporal scale-free nature inherent in this hierarchy of organizational levels for living entities.

Heavy metal contamination and ecological risk of farmland soils adjoining steel plants in Tangshan, Hebei, China.

Science.gov (United States)

Yang, Liyun; Yang, Maomao; Wang, Liping; Peng, Fei; Li, Yuan; Bai, Hao

2018-01-01

The purpose of this study was to determine the heavy metal concentrations and ecological risks to farmland soils caused by atmospheric deposition adjoining five industrial steel districts in Tangshan, Hebei, China. A total of 39 topsoil samples from adjoining these plants were collected and analyzed for Pb, Zn, Cu, Cr, and As. The geo-accumulation index (Igeo) and potential ecological risk index (PERI) were calculated to assess the heavy metal pollution level in soils. The results showed that the levels of Pb and As in farmland soils adjoining all steel plants were more than the background value, with the As content being excessively high. The Cr and Cu contents of some samples were over the background values, but the Zn content was not. In all the research areas, the largest Igeo value of the heavy metals was for As, followed by Pb, and the largest monomial PERI ([Formula: see text]) was As, which showed that the pollution of As in farmland soils was significant and had considerable ecological risk. Additionally, the heavy metal sequential extraction experiments showed that Pb and Cr, which exceeded the background value, were present in about 20% of the exchangeable and carbonate-bound fractions in the soils surrounding some steel plants. This would imply the risk of these heavy metals being absorbed and accumulated by the crops. Therefore, the local government needs to control the pollution of heavy metals in the farmland soils adjoining the steel plant as soon as possible, in order to avoid possible ecological and food safety risks.

Ecological risk assessment: Lessons learned?

International Nuclear Information System (INIS)

Anon.

1993-01-01

This conference was held November 14--18, 1993 in Houston, Texas for the purpose of providing a forum for exchange of state-of-the-art information on ecological risk assessment. This book is comprised of the abstracts of the presentations at this symposium. Individual abstracts have been processed separately for inclusion in the appropriate data bases

An integrated framework for health and ecological risk assessment

International Nuclear Information System (INIS)

Suter, Glenn W.; Vermeire, Theo; Munns, Wayne R.; Sekizawa, Jun

2005-01-01

The worldHealth Organization's (WHO's) International Program for Chemical Safety has developed a framework for performing risk assessments that integrate the assessment of risks to human health and risks to nonhuman organisms and ecosystems. The WHO's framework recognizes that stakeholders and risk managers have their own processes that are parallel to the scientific process of risk assessment and may interact with the risk assessment at various points, depending on the context. Integration of health and ecology provides consistent expressions of assessment results, incorporates the interdependence of humans and the environment, uses sentinel organisms, and improves the efficiency and quality of assessments relative to independent human health and ecological risk assessments. The advantage of the framework to toxicologists lies in the opportunity to use understanding of toxicokinetics and toxicodynamics to inform the integrated assessment of all exposed species

A regional-scale ecological risk framework for environmental flow evaluations

Science.gov (United States)

O'Brien, Gordon C.; Dickens, Chris; Hines, Eleanor; Wepener, Victor; Stassen, Retha; Quayle, Leo; Fouchy, Kelly; MacKenzie, James; Graham, P. Mark; Landis, Wayne G.

2018-02-01

Environmental flow (E-flow) frameworks advocate holistic, regional-scale, probabilistic E-flow assessments that consider flow and non-flow drivers of change in a socio-ecological context as best practice. Regional-scale ecological risk assessments of multiple stressors to social and ecological endpoints, which address ecosystem dynamism, have been undertaken internationally at different spatial scales using the relative-risk model since the mid-1990s. With the recent incorporation of Bayesian belief networks into the relative-risk model, a robust regional-scale ecological risk assessment approach is available that can contribute to achieving the best practice recommendations of E-flow frameworks. PROBFLO is a holistic E-flow assessment method that incorporates the relative-risk model and Bayesian belief networks (BN-RRM) into a transparent probabilistic modelling tool that addresses uncertainty explicitly. PROBFLO has been developed to evaluate the socio-ecological consequences of historical, current and future water resource use scenarios and generate E-flow requirements on regional spatial scales. The approach has been implemented in two regional-scale case studies in Africa where its flexibility and functionality has been demonstrated. In both case studies the evidence-based outcomes facilitated informed environmental management decision making, with trade-off considerations in the context of social and ecological aspirations. This paper presents the PROBFLO approach as applied to the Senqu River catchment in Lesotho and further developments and application in the Mara River catchment in Kenya and Tanzania. The 10 BN-RRM procedural steps incorporated in PROBFLO are demonstrated with examples from both case studies. PROBFLO can contribute to the adaptive management of water resources and contribute to the allocation of resources for sustainable use of resources and address protection requirements.

[Pollution Characteristics and Potential Ecological Risk of Heavy Metals in Urban Surface Water Sediments from Yongkang].

Science.gov (United States)

Qi, Peng; Yu, Shu-quan; Zhang, Chao; Liang, Li-cheng; Che, Ji-lu

2015-12-01

In order to understand the pollution characteristics of heavy metals in surface water sediments of Yongkang, we analyzed the concentrations of 10 heavy metals including Ti, Cr, Mn, Co, Ni, Cu, Zn, As, Pb and Fe in 122 sediment samples, explored the underlying source of heavy metals and then assessed the potential ecological risks of those metals by methods of the index of geo-accumulation and the potential ecological risk. The study results showed that: 10 heavy metal contents followed the order: Fe > Ti > Mn > Zn > Cr > Cu > Ph > Ni > As > Co, all heavy metals except for Ti were 1. 17 to 3.78 times higher than those of Zhejiang Jinhua- Quzhou basin natural soils background values; The concentrations of all heavy metals had a significantly correlation between each other, indicating that those heavy metals had similar sources of pollution, and it mainly came from industrial and vehicle pollutions; The pollution extent of heavy metals in sediments by geo-accumulation index (Igeo) followed the order: Cr > Zn > Ni > Cu > Fe > As > Pb >Mn > Ti, thereinto, Cr, Zn, Cu and Ni were moderately polluted or heavily polluted at some sampling sites; The potential ecological risk of 9 heavy metals in sediments were in the following order: Cu > As > Ni > Cr > Pb > Co > Zn > Mn > Ti, Cu and As contributed the most to the total potential ecological risk, accounting for 22.84% and 21. 62% , others had a total of 55.54% , through the ecological risk assessment, 89. 34% of the potential ecological risk indexes ( RI) were low and 10. 66% were higher. The contamination level of heavy metals in Yongkang was slight in total, but was heavy in local areas.

Do HMO market level factors lead to racial/ethnic disparities in colorectal cancer screening? A comparison between high-risk Asian and Pacific Islander Americans and high-risk whites.

Science.gov (United States)

Ponce, Ninez A; Huh, Soonim; Bastani, Roshan

2005-11-01

Few studies have explored health care market structure and colorectal cancer (CRC) screening test use, and little is known whether market factors contribute to racial/ethnic screening disparities. We investigated whether HMO market level factors, controlling for individual covariates, differentially impact Asian American and Pacific Islander (AAPI) subjects' access to CRC screening compared with white subjects. We used random intercept hierarchical models to predict CRC test use. Individual-level survey data was linked to market data by metropolitan statistical areas from InterStudy. Insured first-degree relatives, ages 40-80, of a random sample of colorectal cancer cases identified from the California Cancer Registry: 515 white subjects and 396 AAPI subjects residing in 36 metropolitan statistical areas (MSAs). Dependent variables were receipt of (1) annual fecal occult blood test only; (2) sigmoidoscopy in the past 5 years; (3) colonoscopy in the past 10 years; and (4) any of these tests over the recommended time interval. Market characteristics were HMO penetration, HMO competition, and proportion of staff/group/network HMOs. Market characteristics were as important as individual-level characteristics for AAPI but not for white subjects. Among AAPI subjects, a 10% increase in the percent of group/staff/network model HMO was associated with a reduction in colonoscopy use (28.9% to 20.5%) and in receipt of any of the CRC tests (53.2% to 45.4%). The prevailing organizational structure of a health care market confers a penalty on access to CRC test use among high-risk AAPI subjects but not among high-risk white subjects. Identifying the differential effect of market structure on race/ethnicity can potentially reduce the cancer burden among disadvantaged racial groups.

[Ecological risk assessment of rural-urban ecotone based on landscape pattern: A case study in Daiyue District of Tai' an City, Shandong Province of East China].

Science.gov (United States)

Shi, Hao-Peng; Yu, Kai-Qin; Feng, Yong-jun

2013-03-01

Based on the remote sensing data in 2000, 2005, and 2010, this paper analyzed the variation trends of the land use type and landscape pattern in Daiyue District of Tai' an City from 2000 to 2010. The ecological risk index was built, that of the District was re-sampled and spatially interpolated, and the spatiotemporal pattern of the ecological risk in the rural-urban ecotone of the District was analyzed. In 2000-2010, the main variation trend of the land use type in the District was the shift from natural landscape to artificial landscape. The intensity of human disturbance was larger in cultivated land, garden plot, and forestland than in other landscape types, while the human disturbance in water area was smaller. The ecological loss degree of cultivated land and water area decreased somewhat, while that of the other land use types presented an increasing trend. The ecological risk distribution in the District was discrete in 2000 and 2010, but most centralized in 2005. The ecological risk of each ecological risk sub-area had an increasing trend in 2000-2005, but was in adverse in 2005-2010. In 2000-2010, the ecological risk of the District was mainly at medium level. Spatially, the distribution of the ecological risk in the District had an obvious differentiation, with an overall diffusive increasing from forestland as the center to the surrounding areas. In the District, the ecological risk was mainly at medium and higher levels, the area with lower ecological risk had an obvious dynamic change, while that with the lowest and highest ecological risk had less change.

Screening Risk Assessment for Possible Radionuclides in the Amchitka Marine Environment

Energy Technology Data Exchange (ETDEWEB)

NNSA/NV

2002-10-31

, the most conservative data were selected. Conservative assumptions and values were used for radionuclide uptake factors and for marine food ingestion rates by human receptors. The dispersion of material in the marine environment utilized a U.S. Environmental Protection Agency (EPA)-approved model (CORMIX). In addition, the screening level of 1 x 10{sup -6} or 1 excess cancer in 1 million is considered by the EPA to be below the level of concern. The end result, as presented in this report, is a highly conservative estimate of potential risks that are well below the EPA's most conservative risk threshold for both subsistence users and commercial-catch consumers.

Elite athletes experiences with risk related to cardiac screening

DEFF Research Database (Denmark)

Christensen, Jonas Schmidt; Thing, Lone Friis

Society of Cardiology as well as major sports federations such as the International Olympic Committee, however, these recommendations seem to be based on an inadequate empirical foundation, just as the costs of performing cardiac screening on a larger scale seem out of proportion. Additionally, the field...... perspective on risk (Foucault 1988). For most elite athletes participation in cardiac screening is done out of a wish to obtain an acquittal from risks. Symptomatic of the risk society cardiac screening can from an athlete perspective at the same time be seen as an attempt to gain control over......Elite Athletes experiences with risks related to Cardiac Screening Jonas Schmidt Christensen1, Lone Friis Thing1 1University of Copenhagen - Department of Nutrition, Exercise and Sports (NEXS), Cardiac screening of elite athletes are recommended by both the American Heart Association & the European...

Ecological and human health sediment risk assessment for a hydrocarbon-impacted site in Lake Athabasca

International Nuclear Information System (INIS)

Mcdonald, B.; Wagenaar, A.; LaPorte, J.; Misfeldt, G.; Chatwell, I.

2009-01-01

The operation of a public port facility near Uranium City, Saskatchewan has resulted in elevated levels of hydrocarbons in soil, groundwater and sediment. Remedial action in the uplands portion of the site was successful and a risk management approach was initiated for the aquatic portion of the site in order to resolve human health and ecological issues. Ecological risks were assessed using a sediment weight-of-evidence approach involving chemistry, toxicity, bioaccumulation and benthic community structure. Human health risks were assessed via fish consumption, water ingestion and direct contact according to Health Canada guidance. This presentation included an overview of the general risk assessment approach as well as site-specific data and findings. The primary focus was on the challenges confronted during the risk assessment process, such as the need to include alkylated PAHs as a COPC in the human health risk assessment and to evaluate ongoing propeller wash and sediment resuspension for sediment risk management, even though the facility is no longer operational.

Ecological and human health risks associated with abandoned gold mine tailings contaminated soil.

Directory of Open Access Journals (Sweden)

Veronica Mpode Ngole-Jeme

Full Text Available Gold mining is a major source of metal and metalloid emissions into the environment. Studies were carried out in Krugersdorp, South Africa, to evaluate the ecological and human health risks associated with exposure to metals and metalloids in mine tailings contaminated soils. Concentrations of arsenic (As, cadmium (Cd, chromium (Cr, cobalt (Co, copper (Cu, lead (Pb, manganese (Mn, nickel (Ni, and zinc (Zn in soil samples from the area varied with the highest contamination factors (expressed as ratio of metal or metalloid concentration in the tailings contaminated soil to that of the control site observed for As (3.5x102, Co (2.8x102 and Ni (1.1x102. Potential ecological risk index values for metals and metalloids determined from soil metal and metalloid concentrations and their respective risk factors were correspondingly highest for As (3.5x103 and Co (1.4x103, whereas Mn (0.6 presented the lowest ecological risk. Human health risk was assessed using Hazard Quotient (HQ, Chronic Hazard Index (CHI and carcinogenic risk levels, where values of HQ > 1, CHI > 1 and carcinogenic risk values > 1×10-4 represent elevated risks. Values for HQ indicated high exposure-related risk for As (53.7, Cr (14.8, Ni (2.2, Zn (2.64 and Mn (1.67. Children were more at risk from heavy metal and metalloid exposure than adults. Cancer-related risks associated with metal and metalloid exposure among children were also higher than in adults with cancer risk values of 3×10-2 and 4×10-2 for As and Ni respectively among children, and 5×10-3 and 4×10-3 for As and Ni respectively among adults. There is significant potential ecological and human health risk associated with metal and metalloid exposure from contaminated soils around gold mine tailings dumps. This could be a potential contributing factor to a setback in the health of residents in informal settlements dominating this mining area as the immune systems of some of these residents are already compromised by high

Sleeping site ecology, but not sex, affect ecto- and hemoparasite risk, in sympatric, arboreal primates (Avahi occidentalis and Lepilemur edwardsi).

Science.gov (United States)

Hokan, May; Strube, Christina; Radespiel, Ute; Zimmermann, Elke

2017-01-01

A central question in evolutionary parasitology is to what extent ecology impacts patterns of parasitism in wild host populations. In this study, we aim to disentangle factors influencing the risk of parasite exposure by exploring the impact of sleeping site ecology on infection with ectoparasites and vector-borne hemoparasites in two sympatric primates endemic to Madagascar. Both species live in the same dry deciduous forest of northwestern Madagascar and cope with the same climatic constraints, they are arboreal, nocturnal, cat-sized and pair-living but differ prominently in sleeping site ecology. The Western woolly lemur ( Avahi occidentalis ) sleeps on open branches and frequently changes sleeping sites, whereas the Milne-Edward's sportive lemur ( Lepilemur edwardsi ) uses tree holes, displaying strong sleeping site fidelity. Sleeping in tree holes should confer protection from mosquito-borne hemoparasites, but should enhance the risk for ectoparasite infestation with mites and nest-adapted ticks. Sex may affect parasite risk in both species comparably, with males bearing a higher risk than females due to an immunosuppressive effect of higher testosterone levels in males or to sex-specific behavior. To explore these hypotheses, ectoparasites and blood samples were collected from 22 individuals of A. occidentalis and 26 individuals of L. edwardsi during the dry and rainy season. L. edwardsi, but not A. occidentalis , harbored ectoparasites, namely ticks ( Haemaphysalis lemuris [Ixodidae], Ornithodoros sp. [Argasidae]) and mites ( Aetholaelaps trilyssa , [Laelapidae]), suggesting that sleeping in tree holes promotes infestation with ectoparasites. Interestingly, ectoparasites were found solely in the hot, rainy season with a prevalence of 75% ( N  = 16 animals). Blood smears were screened for the presence and infection intensity of hemoparasites. Microfilariae were detected in both species. Morphological characteristics suggested that each lemur species

Determining significant endpoints for ecological risk analyses. 1998 annual progress report

Energy Technology Data Exchange (ETDEWEB)

Hinton, T.G.; Congdon, J.; Scott, D. [Univ. of Georgia, Aiken, SC (US). Savannah River Ecology Lab.; Rowe, C. [Univ. of Puerto Rico, San Juan (PR); Bedford, J.; Whicker, W. [Colorado State Univ., Fort Collins, CO (US)

1998-06-01

'The goal of this report is to establish a protocol for assessing risks to non-human populations exposed to environmental stresses typically found on many DOE sites. The authors think that they can achieve this by using novel biological dosimeters in controlled, manipulative dose/effects experiments, and by coupling changes in metabolic rates and energy allocation patterns to meaningful population response variables (such as age-specific survivorship, reproductive output, age at maturity and longevity). This research is needed to determine the relevancy of sublethal cellular damage to the performance of individuals and populations exposed to chronic, low-level radiation, and radiation with concomitant exposure to chemicals. They believe that a scientifically defensible endpoint for measuring ecological risks can only be determined once its understood the extent to which molecular damage from contaminant exposure is detrimental at the individual and population levels of biological organization. The experimental facility will allow them to develop a credible assessment tool for appraising ecological risks, and to evaluate the effects of radionuclide/chemical synergisms on non-human species. This report summarizes work completed midway of a 3-year project that began in November 1996. Emphasis to date has centered on three areas: (1) developing a molecular probe to measure stable chromosomal aberrations known as reciprocal translocations, (2) constructing an irradiation facility where the statistical power inherent in replicated mesocosms can be used to address the response of non-human organisms to exposures from low levels of radiation and metal contaminants, and (3) quantifying responses of organisms living in contaminated mesocosms and field sites.'

Guidance for treatment of variability and uncertainty in ecological risk assessments of contaminated sites

International Nuclear Information System (INIS)

1998-06-01

Uncertainty is a seemingly simple concept that has caused great confusion and conflict in the field of risk assessment. This report offers guidance for the analysis and presentation of variability and uncertainty in ecological risk assessments, an important issue in the remedial investigation and feasibility study processes. This report discusses concepts of probability in terms of variance and uncertainty, describes how these concepts differ in ecological risk assessment from human health risk assessment, and describes probabilistic aspects of specific ecological risk assessment techniques. The report ends with 17 points to consider in performing an uncertainty analysis for an ecological risk assessment of a contaminated site

Barriers and strategies for identifying and managing risk factors of cardiovascular diseases in levels of preventing, screening, and treating

Directory of Open Access Journals (Sweden)

Saber Azami Aghdash

2015-11-01

Full Text Available Introduction: Cardiovascular diseases (CVD are of the main causes of mortality in the world and impose a heavy economic, social, and health burden on society. Therefore, the objective of this study was to determine the barriers and strategies for identifying and managing risk factors of CVD in levels of preventing, screening, and treating. Methods: During present qualitative study with phenomenological approach, 60 subjects of cardiologists, nurses, patients, and their relatives were selected based on purposive sampling from educational-medical cardiothoracic subspecialty centers. Data were collected using an open-ended questionnaire and was extracted and analyzed with content analysis method. Results: Barriers were divided into three groups of individual barriers (low awareness, delay in referring for treatment and screening, incorrect beliefs, and not caring about health, socio-economic barriers (high costs, lack of resources, mental and psychological pressures, and health care barriers (non-alignment of doctors, being therapy-oriented, managerial and planning weaknesses, and lack of health care facilities. The most important presenting strategies are: providing public educations, improving family physician program, reduction of costs, cooperation of patients, and using functional indices to evaluate and improve the quality of services. Conclusion: Low awareness of people, high costs of services, lack of health care facilities, socio-cultural problems of people, and delay in referring of people, for treatment and screening are of the most important barriers of proper identifying and managing risk factors of CVD. Strategies provided in this study to overcome these barriers could be used.

Regional differences in self-reported screening, prevalence and management of cardiovascular risk factors in Switzerland

Science.gov (United States)

2012-01-01

Background In Switzerland, health policies are decided at the local level, but little is known regarding their impact on the screening and management of cardiovascular risk factors (CVRFs). We thus aimed at assessing geographical levels of CVRFs in Switzerland. Methods Swiss Health Survey for 2007 (N = 17,879). Seven administrative regions were defined: West (Leman), West-Central (Mittelland), Zurich, South (Ticino), North-West, East and Central Switzerland. Obesity, smoking, hypertension, dyslipidemia and diabetes prevalence, treatment and screening within the last 12 months were assessed by interview. Results After multivariate adjustment for age, gender, educational level, marital status and Swiss citizenship, no significant differences were found between regions regarding prevalence of obesity or current smoking. Similarly, no differences were found regarding hypertension screening and prevalence. Two thirds of subjects who had been told they had high blood pressure were treated, the lowest treatment rates being found in East Switzerland: odds-ratio and [95% confidence interval] 0.65 [0.50-0.85]. Screening for hypercholesterolemia was more frequently reported in French (Leman) and Italian (Ticino) speaking regions. Four out of ten participants who had been told they had high cholesterol levels were treated and the lowest treatment rates were found in German-speaking regions. Screening for diabetes was higher in Ticino (1.24 [1.09 - 1.42]). Six out of ten participants who had been told they had diabetes were treated, the lowest treatment rates were found for German-speaking regions. Conclusions In Switzerland, cardiovascular risk factor screening and management differ between regions and these differences cannot be accounted for by differences in populations' characteristics. Management of most cardiovascular risk factors could be improved. PMID:22452881

Socio-ecological risk factors for prime-age adult death in two coastal areas of Vietnam.

Science.gov (United States)

Kim, Deok Ryun; Ali, Mohammad; Thiem, Vu Dinh; Wierzba, Thomas F

2014-01-01

Hierarchical spatial models enable the geographic and ecological analysis of health data thereby providing useful information for designing effective health interventions. In this study, we used a Bayesian hierarchical spatial model to evaluate mortality data in Vietnam. The model enabled identification of socio-ecological risk factors and generation of risk maps to better understand the causes and geographic implications of prime-age (15 to less than 45 years) adult death. The study was conducted in two sites: Nha Trang and Hue in Vietnam. The study areas were split into 500×500 meter cells to define neighborhoods. We first extracted socio-demographic data from population databases of the two sites, and then aggregated the data by neighborhood. We used spatial hierarchical model that borrows strength from neighbors for evaluating risk factors and for creating spatially smoothed risk map after adjusting for neighborhood level covariates. The Markov chain Monte Carlo procedure was used to estimate the parameters. Male mortality was more than twice the female mortality. The rates also varied by age and sex. The most frequent cause of mortality was traffic accidents and drowning for men and traffic accidents and suicide for women. Lower education of household heads in the neighborhood was an important risk factor for increased mortality. The mortality was highly variable in space and the socio-ecological risk factors are sensitive to study site and sex. Our study suggests that lower education of the household head is an important predictor for prime age adult mortality. Variability in socio-ecological risk factors and in risk areas by sex make it challenging to design appropriate intervention strategies aimed at decreasing prime-age adult deaths in Vietnam.

Risk-Screening Environmental Indicators (RSEI)

Data.gov (United States)

U.S. Environmental Protection Agency — EPA’s Risk-Screening Environmental Indicators (RSEI) is a geographically-based model that helps policy makers and communities explore data on releases of toxic...

Screening mammography. A risk versus risk decision

International Nuclear Information System (INIS)

Ritenour, E.R.; Hendee, W.R.

1989-01-01

The potential risk of a radiologic procedure often is compared with the potential benefit of the procedure. While risk vs. benefit analysis has been useful as a step toward increased communication and understanding among radiologists, referring physicians, and the general public, it has the disadvantage that risk and benefit are fundamentally different quantities. Hence, their juxtaposition for purposes of comparison presents contextual difficulties. In this article, the concept is presented of comparing the risk of doing a procedure with the risk of choosing not to do the procedure. An example of risk vs. risk analysis of screening mammography for women over the age of 50 is given, with the conclusion that the risk of having yearly mammograms is less than 1/10 the risk of early death caused by failure to diagnose breast cancer by x-ray mammography. This approach to risk analysis would yield interesting data for examinations that are part of more complicated diagnostic pathways.19 references

A Research into Evaluation of Basketball Athletes' Risk Perception Level

Science.gov (United States)

Karatas, Ozgur

2016-01-01

The aim of this study is to compare the risk perception levels of Basketball athletes in Turkish League teams according to some variables. In this research the "general screening model," which is one of the descriptive screening methods, was used. While the population of the study consists of athletes actively engaged in the Turkish…

Evaluation of an inpatient fall risk screening tool to identify the most critical fall risk factors in inpatients.

Science.gov (United States)

Hou, Wen-Hsuan; Kang, Chun-Mei; Ho, Mu-Hsing; Kuo, Jessie Ming-Chuan; Chen, Hsiao-Lien; Chang, Wen-Yin

2017-03-01

To evaluate the accuracy of the inpatient fall risk screening tool and to identify the most critical fall risk factors in inpatients. Variations exist in several screening tools applied in acute care hospitals for examining risk factors for falls and identifying high-risk inpatients. Secondary data analysis. A subset of inpatient data for the period from June 2011-June 2014 was extracted from the nursing information system and adverse event reporting system of an 818-bed teaching medical centre in Taipei. Data were analysed using descriptive statistics, receiver operating characteristic curve analysis and logistic regression analysis. During the study period, 205 fallers and 37,232 nonfallers were identified. The results revealed that the inpatient fall risk screening tool (cut-off point of ≥3) had a low sensitivity level (60%), satisfactory specificity (87%), a positive predictive value of 2·0% and a negative predictive value of 99%. The receiver operating characteristic curve analysis revealed an area under the curve of 0·805 (sensitivity, 71·8%; specificity, 78%). To increase the sensitivity values, the Youden index suggests at least 1·5 points to be the most suitable cut-off point for the inpatient fall risk screening tool. Multivariate logistic regression analysis revealed a considerably increased fall risk in patients with impaired balance and impaired elimination. The fall risk factor was also significantly associated with days of hospital stay and with admission to surgical wards. The findings can raise awareness about the two most critical risk factors for falls among future clinical nurses and other healthcare professionals and thus facilitate the development of fall prevention interventions. This study highlights the needs for redefining the cut-off points of the inpatient fall risk screening tool to effectively identify inpatients at a high risk of falls. Furthermore, inpatients with impaired balance and impaired elimination should be closely

Cd pollution and ecological risk assessment for mining activity zone in Karst Area

Science.gov (United States)

Yang, B.; He, J. L.; Wen, X. M.; Tan, H.

2017-08-01

The monitored soil samples were collected from farmland in the area with mining activity in Karst area in Liupanshui. In this article, moss bag technology and TSP were used simultaneously for Cd transportation and deposition in the study area. Geostatistics and GIS were then used for the spatial distribution of Cd in the soil. Afterwards, Cd pollution to the soil environment and human health was studied by using the geo-accumulation index and potential ecological risk index methods. The results indicated that atmospheric deposition is the major route of Cd pollution. A moderate to strong pollution of Cd in the area and the degree of potential ecological risk was in a high level in the study area. Furthermore, Cd pollution in Liupanshui may originate from mining activity and atmospheric deposition.

Cost Analysis of Universal Screening vs. Risk Factor-Based Screening for Methicillin-Resistant Staphylococcus aureus (MRSA.

Directory of Open Access Journals (Sweden)

Virginia R Roth

Full Text Available The literature remains conflicted regarding the most effective way to screen for MRSA. This study was designed to assess costs associated with universal versus risk factor-based screening for the reduction of nosocomial MRSA transmission.The study was conducted at The Ottawa Hospital, a large multi-centre tertiary care facility with approximately 47,000 admissions annually. From January 2006-December 2007, patients underwent risk factor-based screening for MRSA on admission. From January 2008 to August 2009 universal MRSA screening was implemented. A comparison of costs incurred during risk factor-based screening and universal screening was conducted. The model incorporated probabilities relating to the likelihood of being tested and the results of polymerase chain reaction (PCR testing with associated effects in terms of MRSA bacteremia and true positive and negative test results. Inputted costs included laboratory testing, contact precautions and infection control, private room costs, housekeeping, and length of hospital stay. Deterministic sensitivity analyses were conducted.The risk factor-based MRSA screening program screened approximately 30% of admitted patients and cost the hospital over $780 000 annually. The universal screening program screened approximately 83% of admitted patients and cost over $1.94 million dollars, representing an excess cost of $1.16 million per year. The estimated additional cost per patient screened was $17.76.This analysis demonstrated that a universal MRSA screening program was costly from a hospital perspective and was previously known to not be clinically effective at reducing MRSA transmission. These results may be useful to inform future model-based economic analyses of MRSA interventions.

Multifactorial screening for fall risk in community-dwelling older adults in the primary care office: development of the fall risk assessment & screening tool.

Science.gov (United States)

Renfro, Mindy Oxman; Fehrer, Steven

2011-01-01

Unintentional falls is an increasing public health problem as incidence of falls rises and the population ages. The Centers for Disease Control and Prevention reports that 1 in 3 adults aged 65 years and older will experience a fall this year; 20% to 30% of those who fall will sustain a moderate to severe injury. Physical therapists caring for older adults are usually engaged with these patients after the first injury fall and may have little opportunity to abate fall risk before the injuries occur. This article describes the content selection and development of a simple-to-administer, multifactorial, Fall Risk Assessment & Screening Tool (FRAST), designed specifically for use in primary care settings to identify those older adults with high fall risk. Fall Risk Assessment & Screening Tool incorporates previously validated measures within a new multifactorial tool and includes targeted recommendations for intervention. Development of the multifactorial FRAST used a 5-part process: identification of significant fall risk factors, review of best evidence, selection of items, creation of the scoring grid, and development of a recommended action plan. Fall Risk Assessment & Screening Tool has been developed to assess fall risk in the target population of older adults (older than 65 years) living and ambulating independently in the community. Many fall risk factors have been considered and 15 items selected for inclusion. Fall Risk Assessment & Screening Tool includes 4 previously validated measures to assess balance, depression, falls efficacy, and home safety. Reliability and validity studies of FRAST are under way. Fall risk for community-dwelling older adults is an urgent, multifactorial, public health problem. Providing primary care practitioners (PCPs) with a very simple screening tool is imperative. Fall Risk Assessment & Screening Tool was created to allow for safe, quick, and low-cost administration by minimally trained office staff with interpretation and

Ecological Risk Assessment Process under the Endangered Species Act

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This document provides an overview of the Environmental Protection Agency’s (EPA) ecological risk assessment process for the evaluation of potential risk to endangered and threatened (listed) species from exposure to pesticides.

Monitoring needs to perform ecological risk assessments in Switzerland

Energy Technology Data Exchange (ETDEWEB)

Kraeuchi, N.

1999-07-01

There is enormous pressure to come up with answers to questions asked by politicians and the public concerning the development of the environment and the potential risks society might be confronted with. Forests for example are expected to fulfill specific functions (e.g., timber production, protection of soil and water resources, recreation). As the environmental and social context itself is rapidly changing it is unknown what uses of a forest will appear in the future. The changing social and ecological context under which forestry operates is therefore calling for an appropriate management mode to deal with uncertainties. There is a need to act, monitor the results, learn from the past, adapt to new conditions through planning and to accept a philosophy of managing an ecosystem with the purpose of reducing potential future socio-ecological and environmental risk by understanding potential problems before they arise. Thus, ecosystem-based management must follow established ecological principles and appropriate guidelines must be derived from a thorough understanding of the origin of the risks potentially threatening the forests and the relevant ecosystem processes. In order to evaluate the likelihood that adverse ecological effects may occur as a result of exposure to one or more stressors long-term monitoring data, information, assumptions and uncertainties need to be systematically evaluated and analyzed. This is needed to understand and predict the relationships between stressors and ecological effects in a way that is useful for environmental decision making.

Control mechanisms for ecological-economic systems

CERN Document Server

Burkov, Vladimir N; Shchepkin, Alexander V

2015-01-01

This monograph presents and analyzes the optimization, game-theoretic and simulation models of control mechanisms for ecological-economic systems. It is devoted to integrated assessment mechanisms for total risks and losses, penalty mechanisms, risk payment mechanisms, financing and costs compensation mechanisms for risk level reduction, sales mechanisms for risk level quotas, audit mechanisms, mechanisms for expected losses reduction, economic motivation mechanisms, optimization mechanisms for regional environmental (risk level reduction) programs, and mechanisms for authorities' interests coordination. The book is aiming at undergraduate and postgraduate students, as well as at experts in mathematical modeling and control of ecological economic, socioeconomic and organizational systems.

The Apache Longbow-Hellfire Missile Test at Yuma Proving Ground: Ecological Risk Assessment for Missile Firing

International Nuclear Information System (INIS)

Jones, Daniel Steven; Efroymson, Rebecca Ann; Hargrove, William Walter; Suter, Glenn; Pater, Larry

2008-01-01

A multiple stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60-A1 tanks. This paper describes the ecological risk assessment for the missile launch and detonation. The primary stressor associated with this activity was sound. Other minor stressors included the detonation impact, shrapnel, and fire. Exposure to desert mule deer (Odocoileus hemionus crooki) was quantified using the Army sound contour program BNOISE2, as well as distances from the explosion to deer. Few effects data were available from related studies. Exposure-response models for the characterization of effects consisted of human 'disturbance' and hearing damage thresholds in units of C-weighted decibels (sound exposure level) and a distance-based No Observed Adverse Effects Level for moose and cannonfire. The risk characterization used a weight-of-evidence approach and concluded that risk to mule deer behavior from the missile firing was likely for a negligible number of deer, but that no risk to mule deer abundance and reproduction is expected

[Value of nutritional risk screening in evaluating adverse clinical outcomes in children with severe pneumonia].

Science.gov (United States)

Guo, Xiao-Hui; Sun, Yan-Feng; Wang, Jiang-Bo; Han, Shu-Zhen; Miao, Jing; Cui, Min

2017-03-01

To investigate the nutritional risk in children with severe pneumonia using the Screening Tool for the Assessment of Malnutrition in Paediatrics (STAMP) and the association between nutritional risk and adverse clinical outcomes. According to the STAMP score, 216 children with severe pneumonia were classified into high nutritional risk group (HR group; n=98), moderate nutritional risk group (MR group; n=65), and low nutritional risk group (LR group; n=53). Fasting blood samples were collected to measure the levels of insulin-like growth factor-1 (IGF-1), adiponectin, leptin, non-esterified fatty acid (NEFA), albumin, transferrin, prealbumin, and retinol binding protein (RBP). The adverse clinical outcomes were recorded. Compared with the MR and LR groups, the HR group had significantly lower serum levels of IGF-1, leptin, adiponectin, prealbumin, and RBP, as well as a significantly higher serum level of NEFA (Prisk screening has an important value in evaluating the clinical outcome of children with severe pneumonia, and children at a higher nutritional risk tend to have more adverse clinical outcomes.

Polycystic ovary syndrome in Central Australia: Diagnosis and screening of cardiometabolic risk and emotional wellbeing

Science.gov (United States)

Ellis, Emma; Gibson-Helm, Melanie; Boyle, Jacqueline A

2018-04-01

Polycystic ovary syndrome (PCOS) is a common condition that affects fertility, body image and emotional wellbeing in women, as well as significantly increasing a woman’s likelihood of developing type 2 diabetes mellitus (T2DM) and other cardiovascular disease risk factors. The objective of this study was to assess how management of PCOS in an Aboriginal primary care setting aligns with national standards for diagnosis and screening of cardiometabolic risk and emotional wellbeing. We conducted a retrospective clinical audit of 63 women who had PCOS listed as a diagnosis in their clinical record. Most women (95%) were correctly diagnosed, the most common trigger being menstrual irregularity (83%). Screening for cardiometabolic complications and emotional wellbeing as recommended by the national guideline was applied inconsistently, including 38% of eligible women not being screened for T2DM in the previous 12 months, and no woman being formally screened for emotional wellbeing. Discussion of lifestyle management was nearly universal; most women (75%) were referred to a dietician, although a third did not attend their appointment. Some components of recommended PCOS care were provided at high levels, including correct application of diagnostic criteria. However, PCOS management and screening for complications are being applied inconsistently in a population with high levels of cardiometabolic and emotional wellbeing risk.

Baseline ecological risk assessment and remediation alternatives for a hydrocarbon-contaminated estuarine wetland

International Nuclear Information System (INIS)

Vedagiri, U.

1993-01-01

Prior to a property transaction, the groundwater at an industrial refinery site in New Jersey was found to be contaminated with a variety of petroleum-based organic compounds. The highly built-up site included an on-site estuarine wetland and was located in a developed, industrialized area near ecologically important estuarine marshes. A preliminary ecological risk assessment was developed on the basis of available data on site contamination and ecological resources. The onsite wetland and its user fauna were identified as the sensitive receptors of concern and the primary contaminant pathways wee identified. The ecological significance of the contamination was assessed with regard to the onsite wetland and in the context of its position within the landscape and surrounding land uses. The wetland exhibited a combination of impact and vitality, i.e., there were clearly visible signs of contaminant impact as well as a relatively complex and abundant food web. Because of its position within the developed landscape, the onsite wetland appeared to function as a refugium for wildlife despite the level of disturbance. The feasibility of achieving regulatory compliance through natural remediation was also examined with respect to the findings of the risk assessment and the resultant conclusions are discussed

[Assessment of heavy metal pollution and potential ecological risks of urban soils in Kaifeng City, China].

Science.gov (United States)

Li, Yi-Meng; Ma, Jian-Hua; Liu, De-Xin; Sun, Yan-Li; Chen, Yan-Fang

2015-03-01

Ninety-nine topsoil (0-15 cm) samples were collected from Kaifeng City, China using the grid method, and then the concentrations of As, Cd, Cr, Cu, Ni, Pb and Zn in the samples were measured by standard methods. Soil pollution levels and potential ecological risks of the heavy metals were assessed using the pollution load index (PLI) and potential ecological risk index (RI), respectively. Ordinary Kriging interpolation technique was employed to investigate the spatial distribution of PLI and RI of the city. The results showed that high pollution of Cd occurred in Kaifeng urban soils, and there was moderate pollution of Zn, slight pollution of Pb and Cu, and no pollution of Ni, Cr and As. Very high ecological risk was posed by Cd and low risk by other metals. The mean PLI of the 7 metals from all sample points was 2.53, which was categorized as moderate pollution. The average RI was 344.58 which represented a considerable ecological risk. PLI and RI shared a similar spatial distribution with high values centralized in the old industrial area in the southeast and railway stations for passengers and goods in the south of the city, followed by the old town within the ancient city wall, and low values located in the north and west areas. Cadmium was the main factor for both soil pollution and potential ecological risk primarily due to farmland topsoil in the eastern suburb of Kaifeng City with high Cd concentrations resulted from sewage irrigation deposited in the urban area by wind, human activities such as soot discharged from the chemical fertilizer plant of Kaifeng, transportation and coal combustion.

Uncertainty in ecological risk assessment: A statistician's view

International Nuclear Information System (INIS)

Smith, E.P.

1995-01-01

Uncertainty is a topic that has different meanings to researchers, modelers, managers and policy makers. The perspective of this presentation will be on the modeling view of uncertainty and its quantitative assessment. The goal is to provide some insight into how a statistician visualizes and addresses the issue of uncertainty in ecological risk assessment problems. In ecological risk assessment, uncertainty arises from many sources and is of different type depending on what is studies, where it is studied and how it is studied. Some major sources and their impact are described. A variety of quantitative approaches to modeling uncertainty are characterized and a general taxonomy given. Examples of risk assessments of lake acidification, power plant impact assessment and the setting of standards for chemicals will be used discuss approaches to quantitative assessment of uncertainty and some of the potential difficulties

Risk-benefit analysis of 18FDG PET cancer screening

International Nuclear Information System (INIS)

Murano, Takeshi; Daisaki, Hiromitsu; Terauchi, Takashi; Iinuma, Takeshi; Tateno, Yukio; Tateishi, Ukihide; Kato, Kazuaki; Inoue, Tomio

2008-01-01

The benefits of 18 F-fluorodeoxyglucose ( 18 FDG) positron emission tomography (PET) cancer screening are expected to include a large population of examinees and are intended for a healthy group. Therefore, we attempted to determine the benefit/risk ratio, estimated risk of radiation exposure, and benefit of cancer detection. We used software that embodied the method of the International Commission on Radiological Protection (ICRP) to calculate the average duration of life of radiation exposure. We calculated the lifesaving person years of benefit to be obtained by 18 FDG PET cancer screening detection. We also calculated the benefit/risk ratio using life-shortening and lifesaving person years. According to age, the benefit/risk ratio was more than 1 at 35-39 years old for males and 30-34 years old for females. 18 FDG PET cancer screening also is effective for examinees older than this. A risk-benefit analysis of 18 FDG-PET/computed tomography (CT) cancer screening will be necessary in the future. (author)

Spatial and temporal ecological risk assessment of unionized ammonia nitrogen in Tai Lake, China (2004-2015).

Science.gov (United States)

Li, Yabing; Xu, Elvis Genbo; Liu, Wei; Chen, Yi; Liu, Hongling; Li, Di; Liu, Zhengtao; Giesy, John P; Yu, Hongxia

2017-06-01

Ammonia toxicity varies largely due to its pH- and temperature-dependent speciation (unionized ammonia nitrogen, NH 3 -N). The seasonal and long-term trend of ammonia risk in ecologically significant sections of Tai Lake, China was unknown. In this study, a two-level (deterministic and quantitative) method was developed to assess the special ecological risks posed by NH 3 -N at 37 sites during two seasons (February and September) of 2014 in Tai Lake. The long-term temporal (2004-2015) risk posed by NH 3 -N was also assessed by comparing annual quantitative risk values (probability of exceeding acute or chronic threshold values) in three key sections of Tai Lake. The results indicated the species living in the Tai Lake were at a 0.04% and 32.45% chance of risk due to acute exposure, and a 1.97% and 92.05% chance of risk due to chronic exposure in February and September of 2014, respectively. Alarmingly, the chronic ecological risks of NH 3 -N in the Lanshanzui section of the Tai Lake remained >30% from 2004 to 2011. The chronic risk of NH 3 -N in all three key sections of Tai Lake started to decrease in 2011. This was likely the consequence of the control practice of eutrophication implemented in the Tai Lake. A significant decline in diversity of the benthic invertebrate community of the Tai Lake could be associated with continuous exposure to ammonia over decades given different sensitivity of taxa to ammonia. The results laid a scientific foundation for risk assessment and management of ammonia in Tai Lake, China, and the developed two-level risk assessment approach can also be applied to other similar aquatic regions. Copyright © 2017 Elsevier Inc. All rights reserved.

Ecological risk assessment of depleted uranium in the environment at Aberdeen Proving Ground

International Nuclear Information System (INIS)

Clements, W.H.; Kennedy, P.L.; Myers, O.B.

1993-01-01

A preliminary ecological risk assessment was conducted to evaluate the effects of depleted uranium (DU) in the Aberdeen Proving Ground (APG) ecosystem and its potential for human health effects. An ecological risk assessment of DU should include the processes of hazard identification, dose-response assessment, exposure assessment, and risk characterization. Ecological risk assessments also should explicitly examine risks incurred by nonhuman as well as human populations, because risk assessments based only on human health do not always protect other species. To begin to assess the potential ecological risk of DU release to the environment we modeled DU transport through the principal components of the aquatic ecosystem at APG. We focused on the APG aquatic system because of the close proximity of the Chesapeake Bay and concerns about potential impacts on this ecosystem. Our objective in using a model to estimate environmental fate of DU is to ultimately reduce the uncertainty about predicted ecological risks due to DU from APG. The model functions to summarize information on the structure and functional properties of the APG aquatic system, to provide an exposure assessment by estimating the fate of DU in the environment, and to evaluate the sources of uncertainty about DU transport

Ecological risks of DOE's programmatic environmental restoration alternatives

International Nuclear Information System (INIS)

1994-06-01

This report assesses the ecological risks of the Department of Energy's (DOE) Environmental Restoration Program. The assessment is programmatic in that it is directed at evaluation of the broad programmatic alternatives outlined in the DOE Implementation Plan. It attempts to (1) characterize the ecological resources present on DOE facilities, (2) describe the occurrence and importance of ecologically significant contamination at major DOE facilities, (3) evaluate the adverse ecological impacts of habitat disturbance caused by remedial activities, and (4) determine whether one or another of the programmatic alternatives is clearly ecologically superior to the others. The assessment focuses on six representative facilities: the Idaho National Engineering Laboratory (INEL); the Fernald Environmental Management Project (FEMP); the Oak Ridge Reservation (ORR), including the Oak Ridge National Laboratory (ORNL), Y-12 plant, and K-25 plant; the Rocky Flats Plant; the Hanford Reservation; and the Portsmouth Gaseous Diffusion Plant

The development of an ecological approach to manage the pollution risk from highway runoff.

Science.gov (United States)

Crabtree, B; Dempsey, P; Johnson, I; Whitehead, M

2009-01-01

In the UK, the Highways Agency is responsible for operating, maintaining and improving the strategic road network in England. One focus of the Highways Agency's ongoing research into the nature and impact of highway runoff is aimed at ensuring that the Highways Agency will meet the requirements of the EU Water Framework Directive. A research programme, undertaken in partnership with the Environment Agency, is in progress to develop a better understanding of pollutants in highway runoff and their ecological impact. The paper presents the outcome of a study to: (1) monitor pollutants in highway runoff under different climate and traffic conditions; (2) develop standards to assess potential ecological risks from soluble pollutants in highway runoff; and (3) develop a model to predict pollutant concentrations in highway runoff. The model has been embedded in a design tool incorporating risk assessment procedures and receiving water standards for soluble and insoluble pollutants--the latter has been developed elsewhere in another project within the research programme. The design tool will be used to support improved guidance on where, and to what level, treatment of runoff is required for highway designers to manage the risk of ecological impact from highway runoff.

Integrated presentation of ecological risk from multiple stressors

OpenAIRE

Goussen, Benoit Regis Marc; Price, Oliver R.; Rendal, Cecilie; Ashauer, Roman

2016-01-01

Current environmental risk assessments (ERA) do not account explicitly for ecological factors (e.g. species composition, temperature or food availability) and multiple stressors. Assessing mixtures of chemical and ecological stressors is needed as well as accounting for variability in environmental conditions and uncertainty of data and models. Here we propose a novel probabilistic ERA framework to overcome these limitations, which focusses on visualising assessment outcomes by construct-ing ...

Pollution characteristics and ecological risk assessment of heavy metals in the surface sediments from a source water reservoir

Directory of Open Access Journals (Sweden)

Changming Yang

2016-10-01

Full Text Available Surface sediment samples were collected from a source water reservoir in Zhejiang Province, East of China to investigate pollution characteristics and potential ecological risk of heavy metals. The BCR sequential extraction method was used to determine the four chemical fractions of heavy metals such as acid soluble, easily reducible, easily oxidizable and residual fractions. The heavy metals pollution and potential ecological risk were evaluated systematically using geoaccumulation index (Igeo and Hakanson potential ecological risk index (H′. The results showed that the sampling sites from the estuaries of tributary flowing through downtowns and heavy industrial parks showed significantly (p < 0.05 higher average concentrations of heavy metals in the surface sediments, as compared to the other sampling sites. Chemical fractionation showed that Mn existed mainly in acid extractable fraction, Cu and Pb were mainly in reducible fraction, and As existed mainly in residual fraction in the surface sediments despite sampling sites. The sampling sites from the estuary of tributary flowing through downtown showed significantly (p < 0.05 higher proportions of acid extractable and reducible fractions than the other sampling sites, which would pose a potential toxic risk to aquatic organisms as well as a potential threat to drinking water safety. As, Pb, Ni and Cu were at relatively high potential ecological risk with high Igeo values for some sampling locations. Hakanson potential ecological risk index (H′ showed the surface sediments from the tributary estuaries with high population density and rapid industrial development showed significantly (p < 0.05 higher heavy metal pollution levels and potential ecological risk in the surface sediments, as compared to the other sampling sites.

Ecological risk caused by land use change in the coastal zone: a case study in the Yellow River Delta High-Efficiency Ecological Economic Zone

International Nuclear Information System (INIS)

Di, X H; Wang, Y D; Hou, X Y

2014-01-01

China's coastal zone plays an important role in ecological services production and social-economic development; however, extensive and intensive land resource utilization and land use change have lead to high ecological risk in this area during last decade. Regional ecological risk assessment can provide fundamental knowledge and scientific basis for better understanding of the relationship between regional landscape ecosystem and human activities or climate changes, facilitating the optimization strategy of land use structure and improving the ecological risk prevention capability. In this paper, the Yellow River Delta High-Efficiency Ecological Economic Zone is selected as the study site, which is undergoing a new round of coastal zone exploitation and has endured substantial land use change in the past decade. Land use maps of 2000, 2005 and 2010 were generated based on Landsat images by visual interpretation method, and the ecological risk index was then calculated. The index was 0.3314, 0.3461 and 0.3176 in 2000, 2005 and 2010 respectively, which showed a positive transition of regional ecological risk in 2005

Socio-ecological risk factors for prime-age adult death in two coastal areas of Vietnam.

Directory of Open Access Journals (Sweden)

Deok Ryun Kim

Full Text Available Hierarchical spatial models enable the geographic and ecological analysis of health data thereby providing useful information for designing effective health interventions. In this study, we used a Bayesian hierarchical spatial model to evaluate mortality data in Vietnam. The model enabled identification of socio-ecological risk factors and generation of risk maps to better understand the causes and geographic implications of prime-age (15 to less than 45 years adult death.The study was conducted in two sites: Nha Trang and Hue in Vietnam. The study areas were split into 500×500 meter cells to define neighborhoods. We first extracted socio-demographic data from population databases of the two sites, and then aggregated the data by neighborhood. We used spatial hierarchical model that borrows strength from neighbors for evaluating risk factors and for creating spatially smoothed risk map after adjusting for neighborhood level covariates. The Markov chain Monte Carlo procedure was used to estimate the parameters. Male mortality was more than twice the female mortality. The rates also varied by age and sex. The most frequent cause of mortality was traffic accidents and drowning for men and traffic accidents and suicide for women. Lower education of household heads in the neighborhood was an important risk factor for increased mortality. The mortality was highly variable in space and the socio-ecological risk factors are sensitive to study site and sex.Our study suggests that lower education of the household head is an important predictor for prime age adult mortality. Variability in socio-ecological risk factors and in risk areas by sex make it challenging to design appropriate intervention strategies aimed at decreasing prime-age adult deaths in Vietnam.

Pregnant Women's Perceptions of the Risks and Benefits of Disclosure During Web-Based Mental Health E-Screening Versus Paper-Based Screening: Randomized Controlled Trial.

Science.gov (United States)

Kingston, Dawn; Biringer, Anne; Veldhuyzen van Zanten, Sander; Giallo, Rebecca; McDonald, Sarah; MacQueen, Glenda; Vermeyden, Lydia; Austin, Marie-Paule

2017-10-20

Pregnant women's perceptions of the risks and benefits during mental health screening impact their willingness to disclose concerns. Early research in violence screening suggests that such perceptions may vary by mode of screening, whereby women view the anonymity of e-screening as less risky than other approaches. Understanding whether mode of screening influences perceptions of risk and benefit of disclosure is important in screening implementation. The objective of this randomized controlled trial was to compare the perceptions of pregnant women randomized to a Web-based screening intervention group and a paper-based screening control group on the level of risk and benefit they perceive in disclosing mental health concerns to their prenatal care provider. A secondary objective was to identify factors associated with women's perceptions of risk and benefit of disclosure. Pregnant women recruited from maternity clinics, hospitals, and prenatal classes were computer-randomized to a fully automated Web-based e-screening intervention group or a paper-based control. The intervention group completed the Antenatal Psychosocial Health Assessment and the Edinburgh Postnatal Depression Scale on a computer tablet, whereas the control group completed them on paper. The primary outcome was women's perceptions of the risk and benefits of mental health screening using the Disclosure Expectations Scale (DES). A completer analysis was conducted. Statistical significance was set at Pcontrol (n=331) groups. There were no significant baseline differences between groups. The mode of screening was not associated with either perceived risk or benefit of screening. There were no differences in groups in the mean scores of the risk and benefit of disclosure subscales. Over three-quarters of women in both intervention and control groups perceived that mental health screening was beneficial. However, 43.1% (272/631) of women in both groups reported feeling very, moderately, or somewhat

Modified social ecological model: a tool to guide the assessment of the risks and risk contexts of HIV epidemics.

Science.gov (United States)

Baral, Stefan; Logie, Carmen H; Grosso, Ashley; Wirtz, Andrea L; Beyrer, Chris

2013-05-17

Social and structural factors are now well accepted as determinants of HIV vulnerabilities. These factors are representative of social, economic, organizational and political inequities. Associated with an improved understanding of multiple levels of HIV risk has been the recognition of the need to implement multi-level HIV prevention strategies. Prevention sciences research and programming aiming to decrease HIV incidence requires epidemiologic studies to collect data on multiple levels of risk to inform combination HIV prevention packages. Proximal individual-level risks, such as sharing injection devices and unprotected penile-vaginal or penile-anal sex, are necessary in mediating HIV acquisition and transmission. However, higher order social and structural-level risks can facilitate or reduce HIV transmission on population levels. Data characterizing these risks is often far more actionable than characterizing individual-level risks. We propose a modified social ecological model (MSEM) to help visualize multi-level domains of HIV infection risks and guide the development of epidemiologic HIV studies. Such a model may inform research in epidemiology and prevention sciences, particularly for key populations including men who have sex with men (MSM), people who inject drugs (PID), and sex workers. The MSEM builds on existing frameworks by examining multi-level risk contexts for HIV infection and situating individual HIV infection risks within wider network, community, and public policy contexts as well as epidemic stage. The utility of the MSEM is demonstrated with case studies of HIV risk among PID and MSM. The MSEM is a flexible model for guiding epidemiologic studies among key populations at risk for HIV in diverse sociocultural contexts. Successful HIV prevention strategies for key populations require effective integration of evidence-based biomedical, behavioral, and structural interventions. While the focus of epidemiologic studies has traditionally been on

Ecological and human health risks from metal(loid)s in peri-urban soil in Nanjing, China.

Science.gov (United States)

Ding, Zhuhong; Hu, Xin

2014-06-01

In order to investigate the ecological and human health risks of metal(loid)s (Cu, Pb, Zn, Ni, Cd, Mn, Cr, and As) in peri-urban soils, 43 surface soil samples were collected from the peri-urban area around Nanjing, a megacity in China. The average contents were 1.19, 67.8, 37.6, 105, 167, 44.6, 722, and 50.8 mg kg(-1) for Cd, Cr, Ni, Pb, Zn, Cu, Mn, and As, respectively. A significant positive correlation was found between Cu, Pb, Zn, Cd, Mn, and As (p urban soil samples. Potential ecological risk indices show that the metal(loid)s in the soil could result in higher ecological risks. Cd is the main contributor to the risk, followed by As. The levels of Cu, Pb, Zn, Cd, Mn, and As in stomach and intestinal phases show a positive linear correlation with their total contents. Mn, Zn, Ni, Cd, and Pb in stomach phase showed higher bioaccessibility, while in intestinal phase, Cu, Cr, and As had the higher bioaccessibility. The carcinogenic risk in children and adults posed by As, Pb, and Cr via ingestion was deemed acceptable. The non-carcinogenic risks posed by these metal(loid)s via ingestion to children are higher than to adults and mainly result from As.

Application of ecological risk assessment to establish nonhuman environmental protection at nuclear generating stations in Ontario, Canada

International Nuclear Information System (INIS)

Wismer, D.A.

2004-01-01

A screening ecological risk assessment was performed for regulatory compliance at three Ontario nuclear generating station sites to establish design requirements for a routine contaminant monitoring program and to address the need for non-contaminant stressor management. Site specific assessments went beyond traditional contaminant risk assessment to include stressors associated with land-use change, cooling water systems and site storm water runoff. Valued terrestrial and aquatic ecosystem components were selected from species lists after stakeholder consultation, and contaminants of concern were selected based on their relative loadings, and with respect to regulatory and literature-based benchmarks. Predictive modeling was used to estimate chemical and radionuclide exposures and likelihood of effects. Adverse effects on individual biota were predicted for aqueous emissions of chlorine and storm water but not for radionuclides. Retrospective analyses of past field monitoring were used to determine likelihood of effects from non-contaminant stressors. Individual-level adverse effects were observed for fish losses from cooling water withdrawal. Depending on the site and the biological species, either beneficial or adverse effects from thermal discharge and land-use change were observed. Followup studies include monitoring, laboratory study, computer modeling and mitigation. Field monitoring will generate more precise species-level estimates of intake fish losses, magnitude of fish response to thermal discharge and chlorine concentrations in near-field discharge waters. Laboratory study is determining the effectiveness of intake fish loss mitigation technology. Computer fish population models are being used to design field studies and interpret individual level effects. Mitigation includes storm water controls and habitat biodiversity management projects to offset past losses from site development and construction. Routine contaminant monitoring is planned to

Ecological risk assessment of RAPS waste water disposal in RPS Lake

International Nuclear Information System (INIS)

Verma, P.C.; Hegde, A.G.; Sharma, L.L.; Venkatramani, B.

2007-01-01

The ecological risk assessment is important tool in predicting the likelihood of future adverse effects from a given facility. Ecological risk assessment in itself has several features that contribute to effective environmental decision making for supporting the management actions. This paper attempts to asses the ecological risk evaluated on the basis of thermal ecological studies carried out at Rana Pratap Sagar (RPS) lake during 2002-2005. The study includes monitoring of several water quality parameters, biological and bacterial parameters and data on thermal stratification in respect of RPS reservoir. The monitored data on water quality were subjected to statistical analysis to evaluate the risk. Using fuzzy synthetic evaluation system on the basis of water quality guidelines from WHO, BIS and ICMR with combination of expert perception the water quality belongs to desirable category during all the seasons through out the year. The study reveals that there is no adverse effect on RPS water quality due to release of warmed effluents from Rajasthan Atomic Power Station (RAPS). Moreover, it shows that RPS water is nearly homogeneous and shows weak thermocline and chemocline patterns. Based on monitoring data, the reservoir can be assigned mild eutrophic status. (author)

Ecological risk assessment and carcinogen health risk assessment of arsenic in soils from part area of the Daye City, China

Science.gov (United States)

Li, F.; Wang, T.; Xiao, M. S.; Cai, Y.; Zhuang, Z. Y.

2018-01-01

Soils in four sampling sites from part area of the Daye City were collected. Concentrations of arsenic (As) in soils in sampling sites were detected by Atomic Fluorescence Spectrometry, ecological risk was calculated by potential ecological risk index (RI) and human health risk was measured by human health risk assessment model established by USEPA. The results showed that, the total content of As in soils in Daye was decreased in the order of S4 (66.58 mg/kg)>S2 (44.73 mg/kg)>S3 (34.86 mg/kg) >S1 (21.84 mg/kg), concentrations in all sampling sites were higher than background values of Hubei Province. The potential risk and human health risk were decreased in the order of S4>S2>S3>S1 and S4>S3>S2>S1, respectively. Specially, S1, S2 and S3 were at low potential ecological risk while S4 was at moderate ecological risk. But there was no carcinogenic risk for human exposure to As in soil in Daye.

Cost-effectiveness and radiation risk of breast cancer screening

International Nuclear Information System (INIS)

Rombach, J.J.

1987-01-01

Base cost effectiveness risk associated with radiological screening for tuberculosis and lung tumor the Government of Netherlands advised against mass screening. However, mass screening remains an important method in the case of breast cancer

Ambient volatile organic compounds (VOCs) in Calgary, Alberta: Sources and screening health risk assessment.

Science.gov (United States)

Bari, Md Aynul; Kindzierski, Warren B

2018-08-01

Exposure to ambient volatile organic compound (VOCs) in urban areas is of interest because of their potential chronic and acute adverse effects to public health. Limited information is available about VOC sources in urban areas in Canada. An investigation of ambient VOCs levels, their potential sources and associated risks to public health was undertaken for the urban core of Alberta's largest city (downtown Calgary) for the period 2010-2015. Twenty-four hour arithmetic and geometric mean concentrations of total VOCs were 42μg/m 3 and 39μg/m 3 , respectively and ranged from 16 to 160μg/m 3 , with winter levels about two-fold higher than summer. Alkanes (58%) were the most dominant compounds followed by halogenated VOCs (22%) and aromatics (11%). Mean and maximum 24h ambient concentrations of selected VOCs of public health concern were below chronic and acute health risk screening criteria of the United States regulatory agencies and a cancer screening benchmark used in Alberta equivalent to 1 in 100,000 lifetime risk. The Positive matrix factorization (PMF) model revealed nine VOC sources at downtown Calgary, where oil/natural gas extraction/combustion (26%), fuel combustion (20%), traffic sources including gasoline exhaust, diesel exhaust, mixed fugitive emissions (10-15%), and industrial coatings/solvents (12%) were predominant. Other sources included dry cleaning (3.3%), biogenic (3.5%) and a background source (18%). Source-specific health risk values were also estimated. Estimated cancer risks for all sources were below the Alberta cancer screening benchmark, and estimated non-cancer risks for all sources were well below a safe level. Copyright © 2018 Elsevier B.V. All rights reserved.

Distribution and Ecological Risk Assessment of Heavy Metals in Arable Soils in Bijiang Watershed, China

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HUANG Wei-heng

2017-08-01

Full Text Available It has been paid much attention to soil heavy metal pollution in the Bijiang watershed caused by the Lanping lead-zinc mine. We collected 35 arable soil samples along Bijiang, then sampled and tested the contents of As, Cu, Zn, Cd, Pb, Hg. And then with Nemerow Multi-Factor Index and the Potential Ecological Risk Index method, we evaluated the heavy metal pollution risk. The results showed:(1The accumulation of Pb, Zn, Cd was in a relatively high level, the average was 1 146.97, 579.15, 4.85 mg·kg-1 respectively, which was seriously polluted; the average accumulation of As was 26.85 mg·kg-1; but Cu, Hg was slightly polluted. (2Statistical analysis showed that Lanping area was a main point source pollution of As, Zn, Pb, Cd, while Cu, Hg was pollution caused by different non-point source pollution.(3Within this basin, the Nemerow index was 17.69, which was serious heavy metal pollution, while the comprehensive potential ecological risk index was 773.38, which was a strong potential ecological risk. The contribution of pollutants was Cd > Pb > Zn> As> Hg > Cu. (4As a whole, the soil heavy metal pollution of paddy field was higher than of the dry land.

Feasibility of interdisciplinary community-based fall risk screening.

Science.gov (United States)

Elliott, Sharon J; Ivanescu, Andrada; Leland, Natalie E; Fogo, Jennifer; Painter, Jane A; Trujillo, Leonard G

2012-01-01

This pilot study examined the feasibility of (1) conducting interdisciplinary fall risk screens at a communitywide adult fall prevention event and (2) collecting preliminary follow-up data from people screened at the event about balance confidence and home and activity modifications made after receiving educational information at the event. We conducted a pilot study with pre- and posttesting (4-mo follow-up) with 35 community-dwelling adults ≥55 yr old. Approximately half the participants were at risk for falls. Most participants who anticipated making environmental or activity changes to reduce fall risk initiated changes (n = 8/11; 72.7%) during the 4-mo follow-up period. We found no significant difference in participants' balance confidence between baseline (median = 62.81) and follow-up (median = 64.06) as measured by the Activities-specific Balance Confidence scale. Conducting interdisciplinary fall risk screens at an adult fall prevention event is feasible and can facilitate environmental and behavior changes to reduce fall risk. Copyright © 2012 by the American Occupational Therapy Association, Inc.

Reevaluation of benefit and risk of mass screening for stomach cancer

International Nuclear Information System (INIS)

Iinuma, Takeshi; Tateno, Yukio

1990-01-01

Mass screening for stomach cancer has been performed widely because of the the most prevalent malignancy in Japan. Since X-ray diagnosis is used in stomach cancer screening, the risk of X-ray exposure must be considered by comparing the benefit of mass screening. We have reported in the previous article in 1977 that the benefit and risk of stomach cancer mass screening become equal at the age of 40 yr. Since then, various conditions of the mass screening for stomach cancer have changed so that reevaluation of the benefit and risk relationship is necessary. The risk coefficient of radiation-induced stomach cancer has been revised drastically in the report of United Nations Scientific Committee on the effects of radiation in 1988. In this report, the benefit of mass screening of stomach cancer is defined as the net elongation of average life expectancy due to the life saved, and the risk of the screening is defined as the net shortage of average life expectancy due to the radiation-induced stomach cancer and leukemia. Since the benefit increases rapidly and the risk decreases with age, an appropriate age when the benefit and risk become identical is required, and under this age the mass screening is not justified to be performed. Assuming X-ray dose equivalent to stomach of 10 mSv and risk coefficient of stomach cancer of 12.6x10 -3 Sv -1 from the United Nations report, the critical age is found to be about 35 yr. for men and women. It is strongly recommended that the dose equivalent should be lowered less than 5 mSv. In a calculation of the risk of endoscopic examination in mass screening using reported figures of fatal accident (1.6x10 -5 ) and severe injury (48x10 -5 ) of the stomach endoscopic examination, the critical ages are found to be 40 yr for men and 45 yr for women which are higher than those with X-rays. A screening test using stomach endoscopy cannot be accepted. (J.P.N.)

Ecological risk assessment for the terrestrial ecosystem under chronic radioactive pollution - Ecological risk assessment for the biota on regional radioactive waste storage

Energy Technology Data Exchange (ETDEWEB)

Lavrentyeva, G.V.; Synzynys, B.I.; Shoshina, R.R.; Mirzeabasov, O.A. [Obninsk Institute for Nuclear Power Engineering, branch of the National Research Nuclear University MEPhI, Department of Ecology, Studgorodok,1, 249040 Obninsk, Kaluga region (Russian Federation)

2014-07-01

Now the methods of ecological regulation of a radiation factor from risk assessment are developed poorly. The paper attempts to assess and forecast the terrestrial ecosystem conditions under chronic ionizing radiation by calculating the critical loads. The paper is aimed at developing a methodology to assess the ecological risk for a terrestrial ecosystem under chronic radioactive pollution in a biotope of a regional radioactive waste storage. Objects and Methods: Biotope monitoring of a radioactive waste storage makes clear that the radioecological situation in this territory is stipulated by technogenic {sup 90}Sr found in soil, ground water and biota. Terrestrial mollusks of a shrubby Snail type (Bradybaena fruticum) were chosen as reference species due to their activity to accumulate {sup 90}Sr in shells and the number of colony-forming soil units (CFU) as reference indices. The number of CFU was determined by inoculation of solid medium. Soil and mollusk samples have been collected at most representative sites identified in the previous studies. To assess {sup 90}Sr content in the samples collected, radiochemical separation was used with further radionuclide activity measurements by a 'BETA-01C' scintillation beta-ray spectrometer according to a standard procedure of {sup 90}Sr content assessment from beta-radiation of its daughter radionuclide {sup 90}Y. Ecological risk was calculated from analyzed critical loads using a 'dose-effect' dependence. Statistical data processing was realized with Excell 2007 and R software programs [R Development Core Team, 2010]. The software R was also used for GIS creation. Results and Discussion: A methodology of ecological risk assessment for the terrestrial ecosystem under chronic radioactive pollution of a biotope near a regional radioactive waste storage has been developed in terms of the critical environmental loads analyzed. It consists of five stages: determination of effect indicators and assessment

Vulnerability and risk of deltaic social-ecological systems exposed to multiple hazards.

Science.gov (United States)

Hagenlocher, Michael; Renaud, Fabrice G; Haas, Susanne; Sebesvari, Zita

2018-08-01

Coastal river deltas are hotspots of global change impacts. Sustainable delta futures are increasingly threatened due to rising hazard exposure combined with high vulnerabilities of deltaic social-ecological systems. While the need for integrated multi-hazard approaches has been clearly articulated, studies on vulnerability and risk in deltas either focus on local case studies or single hazards and do not apply a social-ecological systems perspective. As a result, vulnerabilities and risks in areas with strong social and ecological coupling, such as coastal deltas, are not fully understood and the identification of risk reduction and adaptation strategies are often based on incomplete assumptions. To overcome these limitations, we propose an innovative modular indicator library-based approach for the assessment of multi-hazard risk of social-ecological systems across and within coastal deltas globally, and apply it to the Amazon, Ganges-Brahmaputra-Meghna (GBM), and Mekong deltas. Results show that multi-hazard risk is highest in the GBM delta and lowest in the Amazon delta. The analysis reveals major differences between social and environmental vulnerability across the three deltas, notably in the Mekong and the GBM deltas where environmental vulnerability is significantly higher than social vulnerability. Hotspots and drivers of risk vary spatially, thus calling for spatially targeted risk reduction and adaptation strategies within the deltas. Ecosystems have been identified as both an important element at risk as well as an entry point for risk reduction and adaptation strategies. Copyright © 2018. Published by Elsevier B.V.

Is mammography screening history a predictor of future breast cancer risk?

DEFF Research Database (Denmark)

Andersen, Sune Bangsbøll; Törnberg, Sven; Kilpeläinen, Sini

2015-01-01

Inspired by the model by Walter and Day for risk of cervical cancer following negative screens, one might hypothesize that women in a mammography screening programme with a certain number of negative screens had a lower remaining breast cancer risk than that of women in general. We studied whether...... number of negative screens was a predictor for a low remaining breast cancer risk in women participating in the mammography screening programmes in Stockholm, Copenhagen and Funen. Data were collected from the mammography screening programmes in Stockholm, Sweden (1989-2012), Copenhagen, Denmark (1991......-2009) and Funen, Denmark (1993-2009), and linked to the respective cancer registries. We calculated cumulative hazard rates for breast cancer in women in cohorts defined by age at entry and number of negative screens for the maximum follow-up period in each screening centre. For all centres and cohorts...

A Quick Drinking Screen for identifying women at risk for an alcohol-exposed pregnancy.

Science.gov (United States)

Dum, Mariam; Sobell, Linda Carter; Sobell, Mark B; Heinecke, Nicholas; Voluse, Andrew; Johnson, Kenneth

2009-09-01

Two previous studies comparing the Quick Drinking Screen (QDS) with the Timeline Followback (TLFB) found that these two instruments yielded similar reports of alcohol use for clinical and nonclinical populations of problem drinkers. The current study evaluated the correspondence between these two drinking measures with women at risk of an Alcohol-Exposed Pregnancy (AEP). Participants were 355 women who voluntarily participated in a research study during 2005 through 2007 designed to prevent AEPs. All women were screened by phone for eligibility using the QDS and approximately 2 weeks later completed a 3-month TLFB by mail. Results of this study, analyzed in 2008, paralleled previous studies showing that the QDS and the TLFB, two very different drinking measures, collected similar aggregate drinking data for women who drink heavily and are at risk of an AEP. Correspondence between the two drinking measures met acceptable levels of reliability. The present study found that the QDS has demonstrated efficacy for screening women whose level of alcohol use puts them at risk for an AEP. Although the QDS does not yield detailed drinking information, it could be used when it is not possible or necessary to gather daily drinking data.

Ecological risk assessment of microcystin-LR in the upstream section of the Haihe River based on a species sensitivity distribution model.

Science.gov (United States)

Niu, Zhiguang; Du, Lei; Li, Jiafu; Zhang, Ying; Lv, Zhiwei

2018-02-01

The eutrophication of surface water has been the main problem of water quality management in recent decades, and the ecological risk of microcystin-LR (MC-LR), which is the by-product of eutrophication, has drawn more attention worldwide. The aims of our study were to determine the predicted no effect concentration (PNEC) of MC-LR and to assess the ecological risk of MC-LR in the upstream section of the Haihe River. HC 5 (hazardous concentration for 5% of biological species) and PNEC were obtained from a species sensitivity distribution (SSD) model, which was constructed with the acute toxicity data of MC-LR on aquatic organisms. The concentrations of MC-LR in the upstream section of the Haihe River from April to August of 2015 were analysed, and the ecological risk characteristics of MC-LR were evaluated based on the SSD model. The results showed that the HC 5 of MC-LR in freshwater was 17.18 μg/L and PNEC was 5.73 μg/L. The concentrations of MC-LR ranged from 0.68 μg/L to 32.21 μg/L and were obviously higher in summer than in spring. The values of the risk quotient (RQ) ranged from 0.12 to 5.62, suggesting that the risk of MC-LR for aquatic organisms in the river was at a medium or high level during the study period. Compared with other waterbodies in the world, the pollution level of MC-LR in the Haihe River was at a moderate level. This research could promote the study of the ecological risk of MC-LR at the ecosystem level. Copyright © 2017 Elsevier Ltd. All rights reserved.

Ecological risk of methylmercury to piscivorous fish of the Great Lakes region.

Science.gov (United States)

Sandheinrich, Mark B; Bhavsar, Satyendra P; Bodaly, R A; Drevnick, Paul E; Paul, Eric A

2011-10-01

Contamination of fish populations with methylmercury is common in the region of the Laurentian Great Lakes as a result of atmospheric deposition and methylation of inorganic mercury. Using fish mercury monitoring data from natural resource agencies and information on tissue concentrations injurious to fish, we conducted a screening-level risk assessment of mercury to sexually mature female walleye (Sander vitreus), northern pike (Esox lucius), smallmouth bass (Micropterus dolomieu), and largemouth bass (Micropterus salmoides) in the Great Lakes and in interior lakes, impoundments, and rivers of the Great Lakes region. The assessment included more than 43,000 measurements of mercury in fish from more than 2000 locations. Sexually mature female fish that exceeded threshold-effect tissue concentrations of 0.20 μg g(-1) wet weight in the whole body occurred at 8% (largemouth bass) to 43% (walleye) of sites. Fish at 3% to 18% of sites were at risk of injury and exceeded 0.30 μg g(-1) where an alteration in reproduction or survival is predicted to occur. Most fish at increased risk were from interior lakes and impoundments. In the Great Lakes, no sites had sexually mature fish that exceeded threshold-effect concentrations. Results of this screening-level assessment indicate that fish at a substantive number of locations within the Great Lakes region are potentially at risk from methylmercury contamination and would benefit from reduction in mercury concentrations.

Lung Cancer Screening May Benefit Those at Highest Risk

Science.gov (United States)

People at the highest risk for lung cancer, based on a risk model, may be more likely to benefit from screening with low-dose CT, a new analysis suggests. The study authors believe the findings may better define who should undergo lung cancer screening, as this Cancer Currents blog post explains.

Software Tool Implementing the Fuzzy AHP Method in Ecological Risk Assessment

Directory of Open Access Journals (Sweden)

Radionovs Andrejs

2017-12-01

Full Text Available Due to the increased spread of invasive animals and plants in the territory of Latvia, the necessity of ecological risk assessment related to such kind of spread has grown lately. In cases with sufficient statistical data, the risk assessment may be successfully performed on the basis of statistical methods. The amount of statistical data in the context of spread of invasive animals and plants is pretty poor; therefore, the only method of ecological risk assessment remains subjective judgements of experts. The present paper proposes using a programming tool for ecological risk analysis elaborated by the authors. With the help of this programming tool the method of Fuzzy Analytical Hierarchical Process is implemented. The elements of the pairwise comparison matrix are allowed to be expressed by triangular and trapezoidal fuzzy sets. The presented tool makes it possible to design the fuzzy pair-wise comparison matrix and process the results in a user-friendly way.

Demonstration of the Military Ecological Risk Assessment Framework (MERAF): Apache Longbow - Hell Missile Test at Yuma Proving Ground

Energy Technology Data Exchange (ETDEWEB)

Efroymson, R.A.

2002-05-09

This ecological risk assessment for a testing program at Yuma Proving Ground, Arizona, is a demonstration of the Military Ecological Risk Assessment Framework (MERAF; Suter et al. 2001). The demonstration is intended to illustrate how risk assessment guidance concerning-generic military training and testing activities and guidance concerning a specific type of activity (e.g., low-altitude aircraft overflights) may be implemented at a military installation. MERAF was developed with funding from the Strategic Research and Development Program (SERDP) of the Department of Defense. Novel aspects of MERAF include: (1) the assessment of risks from physical stressors using an ecological risk assessment framework, (2) the consideration of contingent or indirect effects of stressors (e.g., population-level effects that are derived from habitat or hydrological changes), (3) the integration of risks associated with different component activities or stressors, (4) the emphasis on quantitative risk estimates and estimates of uncertainty, and (5) the modularity of design, permitting components of the framework to be used in various military risk assessments that include similar activities. The particular subject of this report is the assessment of ecological risks associated with a testing program at Cibola Range of Yuma Proving Ground, Arizona. The program involves an Apache Longbow helicopter firing Hellfire missiles at moving targets, i.e., M60-A1 tanks. Thus, the three component activities of the Apache-Hellfire test were: (1) helicopter overflight, (2) missile firing, and (3) tracked vehicle movement. The demonstration was limited, to two ecological endpoint entities (i.e., potentially susceptible and valued populations or communities): woody desert wash communities and mule deer populations. The core assessment area is composed of about 126 km{sup 2} between the Chocolate and Middle Mountains. The core time of the program is a three-week period, including fourteen days of

Demonstration of the Military Ecological Risk Assessment Framework (MERAF): Apache Longbow - Hell Missile Test at Yuma Proving Ground

International Nuclear Information System (INIS)

Efroymson, R.A.

2002-01-01

This ecological risk assessment for a testing program at Yuma Proving Ground, Arizona, is a demonstration of the Military Ecological Risk Assessment Framework (MERAF; Suter et al. 2001). The demonstration is intended to illustrate how risk assessment guidance concerning-generic military training and testing activities and guidance concerning a specific type of activity (e.g., low-altitude aircraft overflights) may be implemented at a military installation. MERAF was developed with funding from the Strategic Research and Development Program (SERDP) of the Department of Defense. Novel aspects of MERAF include: (1) the assessment of risks from physical stressors using an ecological risk assessment framework, (2) the consideration of contingent or indirect effects of stressors (e.g., population-level effects that are derived from habitat or hydrological changes), (3) the integration of risks associated with different component activities or stressors, (4) the emphasis on quantitative risk estimates and estimates of uncertainty, and (5) the modularity of design, permitting components of the framework to be used in various military risk assessments that include similar activities. The particular subject of this report is the assessment of ecological risks associated with a testing program at Cibola Range of Yuma Proving Ground, Arizona. The program involves an Apache Longbow helicopter firing Hellfire missiles at moving targets, i.e., M60-A1 tanks. Thus, the three component activities of the Apache-Hellfire test were: (1) helicopter overflight, (2) missile firing, and (3) tracked vehicle movement. The demonstration was limited, to two ecological endpoint entities (i.e., potentially susceptible and valued populations or communities): woody desert wash communities and mule deer populations. The core assessment area is composed of about 126 km 2 between the Chocolate and Middle Mountains. The core time of the program is a three-week period, including fourteen days of

Feasibility and utility of mapping disease risk at the neighbourhood level within a Canadian public health unit: an ecological study

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Wanigaratne Susitha

2010-05-01

Full Text Available Abstract Background We conducted spatial analyses to determine the geographic variation of cancer at the neighbourhood level (dissemination areas or DAs within the area of a single Ontario public health unit, Wellington-Dufferin-Guelph, covering a population of 238,326 inhabitants. Cancer incidence data between 1999 and 2003 were obtained from the Ontario Cancer Registry and were geocoded down to the level of DA using the enhanced Postal Code Conversion File. The 2001 Census of Canada provided information on the size and age-sex structure of the population at the DA level, in addition to information about selected census covariates, such as average neighbourhood income. Results Age standardized incidence ratios for cancer and the prevalence of census covariates were calculated for each of 331 dissemination areas in Wellington-Dufferin-Guelph. The standardized incidence ratios (SIR for cancer varied dramatically across the dissemination areas. However, application of the Moran's I statistic, a popular index of spatial autocorrelation, suggested significant spatial patterns for only two cancers, lung and prostate, both in males (p Conclusion This paper demonstrates the feasibility and utility of a systematic approach to identifying neighbourhoods, within the area served by a public health unit, that have significantly higher risks of cancer. This exploratory, ecologic study suggests several hypotheses for these spatial patterns that warrant further investigations. To the best of our knowledge, this is the first Canadian study published in the peer-reviewed literature estimating the risk of relatively rare public health outcomes at a very small areal level, namely dissemination areas.

Assessment of metals contamination and ecological risk in ait Ammar abandoned iron mine soil, Morocco

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Nouri Mohamed

2016-03-01

Full Text Available The present study is an attempt to assess the pollution intensity and corresponding ecological risk of phosphorus and metals including Cd, Cr, Cu, Zn, Pb and Fe using various indices like geo-accumulation index, enrichment factor, pollution and ecological risk index. In all, 20 surface soil samples were collected from the Ait Ammar iron mine of Oued Zem city, province of Khouribga, in central Morocco. The concentrations of heavy metals in soil samples were used to assess their potential ecological risks. According to the results of potential ecological risk index (RI, pollution index (PI, geo-accumulation index (Igeo, enrichment factor (EF, potential contamination index (Cp, contaminant factor (Cf and degree of contamination (Cd, based on the averages, considerable pollution of metals in soils of study area was observed. The consequence of the correlation matrix and principal component analysis (PCA indicated that Fe, Cu, Zn, Cr and P mainly originated from natural sources and Cd and Pb are mostly derived from anthropogenic sources. The results showed that these metals in soil were ranked by severity of ecological risk as Pb > Cd > Cu > Cr > Zn, based on their single-element indexes. In view of the potential ecological risk (RI, soils from all soil samples showed a potential ecological risk. These results will provide basic information for the improvement of soil environment management and heavy metal pollution prevention in Ait Ammar.

Spatial distributions, fractionation characteristics, and ecological risk assessment of trace elements in sediments of Chaohu Lake, a large eutrophic freshwater lake in eastern China.

Science.gov (United States)

Wu, Lei; Liu, Guijian; Zhou, Chuncai; Liu, Rongqiong; Xi, Shanshan; Da, Chunnian; Liu, Fei

2018-01-01

The concentrations, spatial distribution, fractionation characteristics, and potential ecological risks of trace elements (Cu, Pb, Zn, Cr, Ni, and Co) in the surface sediment samples collected from 32 sites in Chaohu Lake were investigated. The improved BCR sequential extraction procedure was applied to analyze the chemical forms of trace elements in sediments. The enrichment factor (EF), sediment quality guidelines (SQGs), potential ecological risk index (PERI), and risk assessment code (RAC) were employed to evaluate the pollution levels and the potential ecological risks. The results found that the concentrations of Cu, Pb, Zn, Cr, Ni, and Co in the surface sediments were 78.59, 36.91, 161.84, 98.87, 38.92, and 10.09 mg kg -1 , respectively. The lower concentrations of Cu, Pb, Zn, Cr, and Ni were almost found in the middle part of the lake, while Co increased from the western toward the eastern parts of the lake. Cr, Ni, Co, and Zn predominantly existed in the residual fractions, with the average values of 76.35, 59.22, 45.60, and 44.30%, respectively. Cu and Pb were mainly combined with Fe/Mn oxides in reducible fraction, with the average values of 66.4 and 69.1%, respectively. The pollution levels were different among the selected elements. Cu had the highest potential ecological risk, while Cr had the lowest potential ecological risk.

Polybrominated diphenyl ethers in sewage sludge from Shanghai, China: possible ecological risk applied to agricultural land.

Science.gov (United States)

Yang, Chao; Meng, Xiang-Zhou; Chen, Ling; Xia, Siqing

2011-10-01

Ideally, agricultural use is a treatment for the sewage sludge generated from municipal wastewater. However, this treatment probably causes ecological risks due to the occurrence of organic contaminants in sludge, which has attracted rising concerns recently. To assess the possible ecological risk, in this study, sewage sludge samples were collected from 28 wastewater treatment plants (WWTPs) in Shanghai, China for exploring the level and profile of polybrominated diphenyl ethers (PBDEs). The mean concentration of Σ18PBDE (sum of all target analytes except for BDE-209) was at the low end of global range. However, we found the highest reported BDE-209 levels (34,900 ng g(-1) dw) in sewage sludge/biosoilds to date. The annual mass loadings of penta-BDE, octa-BDE, and deca-BDE were 3.6, 0.6, and 763 kg through sludge, respectively. Following sludge application in agricultural land, the concentrations of penta-BDE, octa-BDE, and deca-BDE in soil were 0.19, 0.03, and 39.5 ng g(-1), respectively. Preliminary results indicate that the ecological risk of soil in organisms exposed to PBDEs was relatively low. Nevertheless, further studies are needed to explore the fate of PBDEs in sewage sludge due to no restriction on the usage and production of PBDEs products in China currently. Copyright © 2011 Elsevier Ltd. All rights reserved.

Combining individual and ecological data to determine compositional and contextual socio-economic risk factors for suicide

DEFF Research Database (Denmark)

Agerbo, Esben; Sterne, J.A.; Gunnell, D.J.

2007-01-01

The social and economic characteristics of geographic areas are associated with their suicide rates. The extent to which these ecological associations are due to the characteristics of the people living in the areas (compositional effects) or the influence of the areas themselves on risk (context......The social and economic characteristics of geographic areas are associated with their suicide rates. The extent to which these ecological associations are due to the characteristics of the people living in the areas (compositional effects) or the influence of the areas themselves on risk...... (contextual effects) is uncertain. Denmark's Medical Register on Vital Statistics and its Integrated Database for Longitudinal Labour Market Research were used to identify suicides and 20 matched controls per case in 25-60-year-old men and women between 1982 and 1997. Individual and area (municipality...... area levels of employment and income and increasing proportions of people living alone were much attenuated after controlling for compositional effects. We found no consistent evidence that associations with individual-level risk factors differed depending on the areas' characteristics (cross...

Pesticide Cumulative Risk Assessment: Framework for Screening Analysis

Science.gov (United States)

This document provides guidance on how to screen groups of pesticides for cumulative evaluation using a two-step approach: begin with evaluation of available toxicological information and, if necessary, follow up with a risk-based screening approach.

Genetic variation of Lymnaea stagnalis tolerance to copper: A test of selection hypotheses and its relevance for ecological risk assessment

International Nuclear Information System (INIS)

Côte, Jessica; Bouétard, Anthony; Pronost, Yannick; Besnard, Anne-Laure; Coke, Maïra; Piquet, Fabien; Caquet, Thierry; Coutellec, Marie-Agnès

2015-01-01

The use of standardized monospecific testing to assess the ecological risk of chemicals implicitly relies on the strong assumption that intraspecific variation in sensitivity is negligible or irrelevant in this context. In this study, we investigated genetic variation in copper sensitivity of the freshwater snail Lymnaea stagnalis, using lineages stemming from eight natural populations or strains found to be genetically differentiated at neutral markers. Copper-induced mortality varied widely among populations, as did the estimated daily death rate and time to 50% mortality (LT50). Population genetic divergence in copper sensitivity was compared to neutral differentiation using the Q ST -F ST approach. No evidence for homogenizing selection could be detected. This result demonstrates that species-level extrapolations from single population studies are highly unreliable. The study provides a simple example of how evolutionary principles could be incorporated into ecotoxicity testing in order to refine ecological risk assessment. - Highlights: • Genetic variation in copper tolerance occurs between Lymnaea stagnalis populations. • We used the Q ST -F ST approach to test evolutionary patterns in copper tolerance. • No evidence for uniform selection was found. • Results suggest that extrapolations to the species level are not safe. • A method is proposed to refine ecological risk assessment using genetic parameters. - Genetic variation in copper tolerance occurs in Lymnaea stagnalis. A method is proposed for considering evolutionary parameters in ecological risk assessment

Overview of representative ecological risk assessments conducted for sites with enhanced radioactivity

International Nuclear Information System (INIS)

Chambers, D.B; Fernandes, S.L.; Phillips, H.A.

2008-01-01

Ionizing radiation is ubiquitous and all living things are, and always have been, exposed to naturally occurring radiation and radioactivity. In addition, human activities have enhanced the natural background levels of radiation and radioactivity globally and, in some cases, locally. Over the past ten or so years, numerous ecological risk assessments (ERAs) have been carried out for a number of sites involving enhanced radiation and radioactivity. The ERAs have examined a range of ecological receptors and have been performed using a variety of approaches, using different assumptions and reference radiation dose rates. A review of representative ERAs selected to encompass a wide range of activities (e.g. uranium mining, nuclear generating stations, waste management sites), locations (e.g. Canada, France, UK, Russia, USA) and ecosystems (terrestrial, freshwater and marine aquatic environments), was completed. The wide range of sites considered in this review demonstrate that the current system of radiological protection has provided an adequate level of protection to populations of non-human biota. (author)

Polycyclic aromatic hydrocarbons (PAH) in superficial water from a tropical estuarine system: Distribution, seasonal variations, sources and ecological risk assessment.

Science.gov (United States)

Santos, Ewerton; Souza, Michel R R; Vilela Junior, Antônio R; Soares, Laiane S; Frena, Morgana; Alexandre, Marcelo R

2018-02-01

This study aimed to evaluate the PAH distribution, sources, seasonal variations and ecological risk assessment in superficial water from the Japaratuba River, Brazil. PAH concentrations ranged from 4 to 119ngL -1 . It was observed that the PAH total concentrations and profiles showed significant differences when comparing the dry season (summer) with the rainy season (winter). Furthermore, most of the PAH originated from pyrogenic sources in the winter, whereas a mixture of sources was observed in the summer. PAH concentration levels found in this study were considered lower than those obtained in other estuarine systems. Ecological risk assessment was determined for individual PAH, based on the risk quotient (RQ) to evaluate the risk of aquatic biota's exposure to PAH. Results suggested that the Japaratuba River has achieved a moderate degree of ecological risk for high molecular weight, showing the importance of identifying these carcinogenic and mutagenic compounds in aquatic systems. Copyright © 2017 Elsevier Ltd. All rights reserved.

The ethics, the risks and the benefits of screening

International Nuclear Information System (INIS)

Miller, A.B.

1989-01-01

The ethical principles underlying screening are reviewed. It is concluded that the ethical requirements for the introduction of screening are stringent, and that screening should not be offered in the absence of unequivocal evidence of effectiveness except in a carefully conducted research study. Part of the reasons for this are the risks associated with screening, which extend beyond the risk of the test itself, to those associated with invitations for screening, false reassurance for false negatives, the diagnostic process and the problem of false positives, and the overtreatment of those with borderline abnormalities. Finally, the benefits expected from screening are considered, especially reduction in mortality from the disease, but also reduction in incidence if a precursor is detected by the test, less radical treatment for cases detected, reassurance for those who test true negative, and resource savings, though it has to be demonstrated that these exceed resource costs

Ecological risks of DOE`s programmatic environmental restoration alternatives

Energy Technology Data Exchange (ETDEWEB)

1994-06-01

This report assesses the ecological risks of the Department of Energy`s (DOE) Environmental Restoration Program. The assessment is programmatic in that it is directed at evaluation of the broad programmatic alternatives outlined in the DOE Implementation Plan. It attempts to (1) characterize the ecological resources present on DOE facilities, (2) describe the occurrence and importance of ecologically significant contamination at major DOE facilities, (3) evaluate the adverse ecological impacts of habitat disturbance caused by remedial activities, and (4) determine whether one or another of the programmatic alternatives is clearly ecologically superior to the others. The assessment focuses on six representative facilities: the Idaho National Engineering Laboratory (INEL); the Fernald Environmental Management Project (FEMP); the Oak Ridge Reservation (ORR), including the Oak Ridge National Laboratory (ORNL), Y-12 plant, and K-25 plant; the Rocky Flats Plant; the Hanford Reservation; and the Portsmouth Gaseous Diffusion Plant.

Integral statistical eco-indices - effective complementary tool for assessment of ecological state of and ecological risks for water ecosystems

International Nuclear Information System (INIS)

Bashamkova, I

2010-01-01

Eco-indices are successfully used for assessment of the ecological state and risks of water reservoirs. They allow, already at early stages, to detect negative effects on water ecosystems caused by progressive anthropogenic impacts and widening of the spectrum of pollutants, and to quantitatively evaluate ecological risks and damage for water reservoirs. Implementing these modern tools to water quality assessment is one of the lines to make decisions concerning challenging environmental problems.

Tailored information about cancer risk and screening: a systematic review.

NARCIS (Netherlands)

Albada, A.; Ausems, M.G.E.M.; Bensing, J.M.; Dulmen, S. van

2009-01-01

OBJECTIVE: To study interventions that provide people with information about cancer risk and about screening that is tailored to their personal characteristics. We assess the tailoring characteristics, theory base and effects on risk perception, knowledge and screening behavior of these

The influence of knowledge and perception of the risk of cervical cancer on screening behavior in mainland Chinese women.

Science.gov (United States)

Gu, Can; Chan, Carmen W H; Twinn, Sheila; Choi, Kai Chow

2012-12-01

Theories of health behavior and empirical research highlight the risk perception as a significant factor for people adopting cancer screening. However, screening uptakes and risk perception of cervical cancer in mainland Chinese women remains unknown. This paper adopted the protection motivation theory (PMT) to examine Chinese women's knowledge and perceptions of cervical cancer risk and factors influencing utilization of cervical screening. A self-administered questionnaire was completed by 167 participants in mainland China (79 nonscreened and 88 screened women) in 2007 which consisted of four sections: background information, women's attendance pattern for cervical screening, perceptions related to body health and knowledge about cervical cancer and screening, and PMT measures. All women considered themselves at low risk of cervical cancer. No significant association was observed between previous screening uptake and PMT variables. Using multivariate analysis, having children, a perception that visiting doctors regularly is important to health, average and high levels of knowledge about cervical screening were significantly associated with having been received screening. Chinese women demonstrated an unrealistic optimism about their personal risk of cervical cancer. The findings do not support an association between risk perception and screening uptake. In spite of this, current findings revealed some possible factors influencing women's screening behavior. This study highlights the significance of knowledge and culturally-relevant health behavior and beliefs about cervical screening for Chinese women in determining whether or not they receive screening. The promotion of cervical cancer prevention and early detection should be integrated into public education about women's health. Copyright © 2011 John Wiley & Sons, Ltd.

[Distribution and risk assessment of mercury species in soil of the water-level-fluctuating zone in the Three Gorges Reservoir].

Science.gov (United States)

Zhang, Cheng; Chen, Hong; Wang, Ding-Yong; Sun, Rong-Guo; Zhang, Jin-Yang

2014-03-01

To investigate pollution level and ecological risk of mercury in soils of the water-level-fluctuating zone in the Three Gorges Reservoir Region, 192 surface soil samples from 14 counties (districts) in Chongqing were obtained. Concentrations of THg and Hg species, bioavailable Hg were analyzed and discussed. Geoaccumulation index (I(geo)) and Håkanson potential ecological risk index (E(r)) were applied to assess the pollution status and potential ecological risk of THg and Hg species, respectively. The results showed that significant differences in the concentration of THg were found in soils of water-level-fluctuating zone in the Three Gorges Reservoir. The THg concentration ranged from 22.4 to 393.5 microg x kg(-1), with an average of (84.2 +/- 54.3) microg x kg(-1). 76.6% of the samples' THg content was higher than the soil background value in the Three Gorges Reservoir Region. The percentage of five mercury species (water-soluble Hg, HCl-soluble Hg, KOH-soluble Hg, H2O2-soluble Hg, residue Hg) in soils were 4.1%, 15.5%, 18.3%, 10.9%, 51.3%, respectively. The average concentrations of bioavailable mercury varied between 19.7-36.6 microg x kg(-1), and the percentage of bioavailable Hg was 22.1%-51.6% of THg. According to the geoaccumulation index, the soils were lightly polluted by Hg. Håkanson single potential ecological risk index evaluation showed that Hg species had a low potential ecological risk, moreover, soils of water-level-fluctuating zone in the Three Gorges Reservoir were at low ecological risk levels as evaluated by bioavailable Hg. While, the assessment results based on THg of soils was much higher than that based on the Hg species. Two methods of evaluation showed that the I(geo) and E(r) values calculated based on the Hg species better reflected the actual pollution levels of soils and its hazard to aquatic organisms.

Sediment Metal Contamination in the Kafue River of Zambia and Ecological Risk Assessment.

Science.gov (United States)

M'kandawire, Ethel; Choongo, Kennedy; Yabe, John; Mwase, Maxwell; Saasa, Ngonda; Nakayama, Shouta M M; Bortey-Sam, Nesta; Blindauer, Claudia A

2017-07-01

Zambia's Kafue River receives wastes from various sources, resulting in metal pollution. This study determined the degree of contamination of 13 metals (Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Cd, Hg and Pb) in Kafue River sediment and the associated ecological risks at six sites in three different seasons. The level of contamination for most metals showed significant site and seasonal differences. The contamination factor and pollution load index indicated that concentrations of most metals particularly copper (Cu), cobalt (Co), manganese (Mn) and arsenic (As) were very high at sites within the Copperbelt mining area. The geoaccumulation index showed an absence of anthropogenic enrichment with Cd and Hg at all the study sites and extreme anthropogenic enrichment with Cu at sites in the Copperbelt mining area. Potential ecological risk showed that Cu and As were likely to cause adverse biological effects to aquatic organisms in the Copperbelt mining region of the Kafue River.

Ecological risk assessment of elemental pollution in sediment from Tunku Abdul Rahman National Park, Sabah

Science.gov (United States)

Elias, Md Suhaimi; Hamzah, Mohd Suhaimi; Rahman, Shamsiah Ab; Salim, Nazaratul Ashifa Abdullah; Siong, Wee Boon; Sanuri, Ezwiza

2014-02-01

Eleven (11) surface sediment samples were collected from Tunku Abdul Rahman National Park, Sabah. The neutron activation analysis (NAA) and inductively coupled plasma-mass spectrometry (ICP-MS) techniques were applied for the determinations metal contents and their distributions in sediment samples. The results shown that Arsenic (As) concentrations are enriched at all sampling stations except for station TAR 09, with enrichment factor (EF) values ranged from 1.1 to 7.2. The elements such as Cd, Cr, Sb and U showed enrichment at a few stations and other elements (Cr, Cu, Pb, Th, Zn) shown as background levels in all stations. Degrees of contamination in this study were calculated base on concentrations of six elements (As, Cd, Cr, Cu, Pb, and Zn). TAR 11 station can be categorized as very high degree of contamination with degree of contamination value of 43.2. TAR 07 station can be categorized as a considerable degree of contamination (contamination value of 16.9). Six stations (TAR 01, 03, 04, 05, 06, 08, 10) showed moderate degree of contamination, with contamination values ranging from 8.0 to 16.0. TAR 02 and TAR 09 stations showed low degree of contaminations (< 8.0). TAR 11 showed very high ecological risk index (RI) with RI value is 916. TAR 07 and TAR 10 showed moderate ecological risk index with RI value 263 and 213, respectively. Other stations showed low ecological risk with RI values ranging from 42.3 to 117 (< 150). Very high ecological risk index could give an adverse effect to the benthic organism. The data obtained from the enrichment factor, degree of contamination and ecological risk index provided vital information, which can be used for future comparison. Information from the present study will be useful to the relevant government agencies and authorities in preparing preventive action to control direct discharge of heavy metals from industries, agro-base activities and domestic waste to the rivers and the sea.

Ecological risk assessment of elemental pollution in sediment from Tunku Abdul Rahman National Park, Sabah

Energy Technology Data Exchange (ETDEWEB)

Elias, Md Suhaimi; Hamzah, Mohd Suhaimi; Rahman, Shamsiah Ab; Salim, Nazaratul Ashifa Abdullah; Siong, Wee Boon; Sanuri, Ezwiza [Analytical Chemistry Application Group, Waste and Environmental Technology Division, Malaysian Nuclear Agency, Bangi 43000, Kajang, Selangor (Malaysia)

2014-02-12

Eleven (11) surface sediment samples were collected from Tunku Abdul Rahman National Park, Sabah. The neutron activation analysis (NAA) and inductively coupled plasma-mass spectrometry (ICP-MS) techniques were applied for the determinations metal contents and their distributions in sediment samples. The results shown that Arsenic (As) concentrations are enriched at all sampling stations except for station TAR 09, with enrichment factor (EF) values ranged from 1.1 to 7.2. The elements such as Cd, Cr, Sb and U showed enrichment at a few stations and other elements (Cr, Cu, Pb, Th, Zn) shown as background levels in all stations. Degrees of contamination in this study were calculated base on concentrations of six elements (As, Cd, Cr, Cu, Pb, and Zn). TAR 11 station can be categorized as very high degree of contamination with degree of contamination value of 43.2. TAR 07 station can be categorized as a considerable degree of contamination (contamination value of 16.9). Six stations (TAR 01, 03, 04, 05, 06, 08, 10) showed moderate degree of contamination, with contamination values ranging from 8.0 to 16.0. TAR 02 and TAR 09 stations showed low degree of contaminations (< 8.0). TAR 11 showed very high ecological risk index (R{sub I}) with RI value is 916. TAR 07 and TAR 10 showed moderate ecological risk index with R{sub I} value 263 and 213, respectively. Other stations showed low ecological risk with RI values ranging from 42.3 to 117 (< 150). Very high ecological risk index could give an adverse effect to the benthic organism. The data obtained from the enrichment factor, degree of contamination and ecological risk index provided vital information, which can be used for future comparison. Information from the present study will be useful to the relevant government agencies and authorities in preparing preventive action to control direct discharge of heavy metals from industries, agro-base activities and domestic waste to the rivers and the sea.

Quantitative influence of risk factors on blood glucose level.

Science.gov (United States)

Chen, Songjing; Luo, Senlin; Pan, Limin; Zhang, Tiemei; Han, Longfei; Zhao, Haixiu

2014-01-01

The aim of this study is to quantitatively analyze the influence of risk factors on the blood glucose level, and to provide theory basis for understanding the characteristics of blood glucose change and confirming the intervention index for type 2 diabetes. The quantitative method is proposed to analyze the influence of risk factors on blood glucose using back propagation (BP) neural network. Ten risk factors are screened first. Then the cohort is divided into nine groups by gender and age. According to the minimum error principle, nine BP models are trained respectively. The quantitative values of the influence of different risk factors on the blood glucose change can be obtained by sensitivity calculation. The experiment results indicate that weight is the leading cause of blood glucose change (0.2449). The second factors are cholesterol, age and triglyceride. The total ratio of these four factors reaches to 77% of the nine screened risk factors. And the sensitivity sequences can provide judgment method for individual intervention. This method can be applied to risk factors quantitative analysis of other diseases and potentially used for clinical practitioners to identify high risk populations for type 2 diabetes as well as other disease.

Spatio-temporal distributions and the ecological and health risks of phthalate esters (PAEs) in the surface water of a large, shallow Chinese lake

Energy Technology Data Exchange (ETDEWEB)

He, Wei; Qin, Ning; Kong, Xiangzhen; Liu, Wenxiu; He, Qishuang; Ouyang, Huiling; Yang, Chen; Jiang, Yujiao; Wang, Qingmei; Yang, Bin; Xu, Fuliu, E-mail: xufl@urban.pku.edu.cn

2013-09-01

The spatio-temporal distributions and the ecological and health risks of PAEs in surface water of Lake Chaohu, the fifth largest lake in China, were studied based on the monthly monitoring of six PAE congeners from May 2010 to April 2011. The annual total concentration of the six PAE congeners (Σ{sub 6}PAE) in the surface water ranged from 0.467 to 17.953 μg L{sup −1}, with the average value of 4.042 ± 3.929 μg L{sup −1}. The di-n-butyl phthalate (DnBP) that dominated the Σ{sub 6}PAE at 65.8% was found at its highest and lowest levels in the western lake (TX) and eastern drinking water source area (JC), respectively. The temporal distributions of Σ{sub 6}PAE showed that the highest and lowest levels were observed in September 2010 and June 2010, respectively. The different relationships between the runoff and the PAEs with low and high levels of carbon might suggest their different sources. The DnBP had much greater ecological risks than the other studied PAE congeners as indicated by its potential affected fractions (PAFs) and the margin of safety (MOS10). The PAE congeners studied posed little health risk to the nearby male and female citizens. - Highlights: • Monthly variation in PAEs was first investigated in a large Chinese shallow lake. • Ecological and health risks with uncertainty were determined. • PAEs with low and high level of carbon would be from different sources. • DnBP predominated within PAE congeners and posed a much greater ecological risks. • The studied PAE congeners posed little health risks to the nearby citizens.

Heavy Metal Contamination and Ecological Risk Assessment of Swine Manure Irrigated Vegetable Soils in Jiangxi Province, China.

Science.gov (United States)

Wang, Maolan; Liu, Ronghao; Lu, Xiuying; Zhu, Ziyi; Wang, Hailin; Jiang, Lei; Liu, Jingjing; Wu, Zhihua

2018-05-01

Heavy metal are often added to animal fodder and accumulate in the soils with swine manure. In this study, heavy metal (Cu, Pb, Cd, Zn, As and Cr) concentrations were determined in agricultural soils irrigated with swine manure in Jiangxi Province, China. Results showed that the average concentrations of Cu, Zn, As and Cr (32.8, 93.7, 21.3 and 75.8 mg/kg, respectively) were higher than the background values, while Pb and Cd (15.2 and 0.090 mg/kg, respectively) were lower than the background values. Contamination factors [Formula: see text] indicated that they were generally moderate for Cu, Zn, As and Cr and generally low for Pb and Cd. The contamination degree (C d ) was calculated to be 7.5-10.0 indicating a moderate degree of contamination. The geoaccumulation index (I geo ) indicated that the soils were unpolluted with Zn, Cd and Pb, while unpolluted to moderately pollute with Cr, Cu and As. The single ecological risk factor [Formula: see text] revealed that the six heavy metals all belonged to low ecological risk. The ecological risk indices suggested that all the sampling sites were at low risk level.

Uncertainty of mass discharge estimation from contaminated sites at screening level

DEFF Research Database (Denmark)

Thomsen, Nanna Isbak; Troldborg, M.; McKnight, Ursula S.

Contaminated sites threaten groundwater resources worldwide. The number of contaminated sites is large and there are too few economic resources available to ensure a thorough investigation and remediation of them all. Risk assessment must already be done at a screening level in order to ensure...... consider possible source and hydrogeological descriptions, where each model is believed to be a realistic representation of the given site, based on the current level of information. Parameter uncertainty is quantified using Monte Carlo simulations. For each conceptual model we calculate a transient mass...

Site-Specific ecological risk assessment. Case-study 2

DEFF Research Database (Denmark)

Jensen, John

“Development of a decision support system for sustainable management of contaminated land by linking bioavailability, ecological risk and ground water pollution of organic pollutants”or in short “LIBERATION”. The presentation includes examples on how to scale and integrate the results from various scientific......The decision supporting and integrating assessment tool, TRIAD, is used site-specific on PAH- and heavy metal contaminated sites in Denmark. The various aspects of the TRIAD approach are used on a set of chemistry-, ecotoxicology- and ecology related data collected among others in the EU project...

Impact of socioeconomic deprivation on screening for cardiovascular disease risk in a primary prevention population: a cross-sectional study.

Science.gov (United States)

Lang, Sarah-Jane; Abel, Gary A; Mant, Jonathan; Mullis, Ricky

2016-03-21

Investigate the association between socioeconomic deprivation and completeness of cardiovascular disease (CVD) risk factor recording in primary care, uptake of screening in people with incomplete risk factor recording and with actual CVD risk within the screened subgroup. Cross-sectional study. Nine UK general practices. 7987 people aged 50-74 years with no CVD diagnosis. CVD risk was estimated using the Framingham equation from data extracted from primary care electronic health records. Where there was insufficient information to calculate risk, patients were invited to attend a screening assessment. Proportion of patients for whom clinical data were sufficiently complete to enable CVD risk to be calculated; proportion of patients invited to screening who attended; proportion of patients who attended screening whose 10-year risk of a cardiovascular event was high (>20%). For each outcome, a set of logistic regression models were run. Crude and adjusted ORs were estimated for person-level deprivation, age, gender and smoking status. We included practice-level deprivation as a continuous variable and practice as a random effect to account for clustering. People who had lower Indices of Multiple Deprivation (IMD) scores (less deprived) had significantly worse routine CVD risk factor recording (adjusted OR 0.97 (0.95 to 1.00) per IMD decile; p=0.042). Screening attendance was poorer in those with more deprivation (adjusted OR 0.89 (0.86 to 0.91) per IMD decile; p20% (OR 1.09 (1.03 to 1.15) per IMD decile; p=0.004). Our data suggest that those who had the most to gain from screening were least likely to attend, potentially exacerbating existing health inequalities. Future research should focus on tailoring the delivery of CVD screening to ensure engagement of socioeconomically deprived groups. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

PROBABILITY SURVEYS , CONDITIONAL PROBABILITIES AND ECOLOGICAL RISK ASSESSMENT

Science.gov (United States)

We show that probability-based environmental resource monitoring programs, such as the U.S. Environmental Protection Agency's (U.S. EPA) Environmental Monitoring and Assessment Program, and conditional probability analysis can serve as a basis for estimating ecological risk over ...

Hydrocarbon Pollution and Potential Ecological Risk of Heavy Metals in the Sediments of the Oturuba Creek, Niger Delta, Nigeria

Directory of Open Access Journals (Sweden)

Ezekwe Clinton Ifeanyichukwu

2017-04-01

Full Text Available This study aimed at examining the impact of oil pollution from artisanal oil refineries on the Oturuba river ecosystem using active river bottom sediment. Specific objectives included to determine the level of hydrocarbons and trace metals (Pb, Cd, Zn, Cu, Ni, V and Mg in the sediments and to relate this with general ecosystem health. The study found elevated concentrations of both hydrocarbons and heavy metals in the range above most sediment quality guidelines exceeding the respective Threshold Effects Level and Probable Effects. Level guideline values and occurring at levels where impairment to biological communities is certain an d where toxicity levels can lead to negative impacts on benthic animals or infaunal communities. Heavy metal geochemical accumulation index and potential ecological risk analysis also returned anomalously high concentrations in the range of very highly polluted sediment environments with very high ecological risk indices, thereby ranking the Oturuba Creek as one of the most polluted coastal river systems in the world.

Ecological risk assessment of heavy metals in sediment and human health risk assessment of heavy metals in fishes in the middle and lower reaches of the Yangtze River basin

Energy Technology Data Exchange (ETDEWEB)

Yi Yujun [State Key Laboratory of Water Environment Simulation and Pollution Control, School of Environment, Beijing Normal University, Beijing 100875 (China); Yang Zhifeng, E-mail: zfyang@bnu.edu.cn [State Key Laboratory of Water Environment Simulation and Pollution Control, School of Environment, Beijing Normal University, Beijing 100875 (China); Zhang Shanghong [Renewable Energy School, North China Electric Power University, Beijing 102206 (China)

2011-10-15

The concentrations of heavy metals (Cr, Cd, Hg, Cu, Zn, Pb and As) in the water, sediment, and fish were investigated in the middle and lower reaches of the Yangtze River, China. Potential ecological risk analysis of sediment heavy metal concentrations indicated that six sites in the middle reach, half of the sites in the lower reach, and two sites in lakes, posed moderate or considerable ecological risk. Health risk analysis of individual heavy metals in fish tissue indicated safe levels for the general population and for fisherman but, in combination, there was a possible risk in terms of total target hazard quotients. Correlation analysis and PCA found that heavy metals (Hg, Cd, Pb, Cr, Cu, and Zn) may be mainly derived from metal processing, electroplating industries, industrial wastewater, and domestic sewage. Hg may also originate from coal combustion. Significant positive correlations between TN and As were observed. - Highlights: > Field survey, test and relationship of the concentrations of heavy metals in the water, sediment, and fish. > Potential ecological risk assessment of heavy metals in sediment. > Non-cancer health risk assessment of heavy metals in fish tissue. > Possible pollution source of heavy metals analyzed. - Possible ecological risk of sediment and slight non-cancer health risk of eating fish were found in the middle and lower reaches of the Yangtze River.

Ecological risk assessment of heavy metals in sediment and human health risk assessment of heavy metals in fishes in the middle and lower reaches of the Yangtze River basin

International Nuclear Information System (INIS)

Yi Yujun; Yang Zhifeng; Zhang Shanghong

2011-01-01

The concentrations of heavy metals (Cr, Cd, Hg, Cu, Zn, Pb and As) in the water, sediment, and fish were investigated in the middle and lower reaches of the Yangtze River, China. Potential ecological risk analysis of sediment heavy metal concentrations indicated that six sites in the middle reach, half of the sites in the lower reach, and two sites in lakes, posed moderate or considerable ecological risk. Health risk analysis of individual heavy metals in fish tissue indicated safe levels for the general population and for fisherman but, in combination, there was a possible risk in terms of total target hazard quotients. Correlation analysis and PCA found that heavy metals (Hg, Cd, Pb, Cr, Cu, and Zn) may be mainly derived from metal processing, electroplating industries, industrial wastewater, and domestic sewage. Hg may also originate from coal combustion. Significant positive correlations between TN and As were observed. - Highlights: → Field survey, test and relationship of the concentrations of heavy metals in the water, sediment, and fish. → Potential ecological risk assessment of heavy metals in sediment. → Non-cancer health risk assessment of heavy metals in fish tissue. → Possible pollution source of heavy metals analyzed. - Possible ecological risk of sediment and slight non-cancer health risk of eating fish were found in the middle and lower reaches of the Yangtze River.

Self-Screening for Malnutrition Risk in Outpatient Inflammatory Bowel Disease Patients Using the Malnutrition Universal Screening Tool (MUST).

Science.gov (United States)

Sandhu, Amindeep; Mosli, Mahmoud; Yan, Brian; Wu, Thomas; Gregor, Jamie; Chande, Nilesh; Ponich, Terry; Beaton, Melanie; Rahman, Adam

2016-05-01

Malnutrition is common in patients with inflammatory bowel disease (IBD) and is associated with poor outcomes. Our aim is to determine if patient self-administered malnutrition screening using the malnutrition universal screening tool (MUST) is reliable by comparing patient scores with those derived from the healthcare practitioner (HCP), the gold standard. We conducted a prospective validation study at a tertiary Canadian academic center that included 154 adult outpatients with IBD. All patients with IBD completed a self-administered nutrition screening assessment using the MUST score followed by an independent MUST assessment performed by HCPs. The main outcome measure was chance-corrected agreement (κ) of malnutrition risk categorization. For patient-administered MUST, the chance-corrected agreement κ (95% confidence interval [CI]) was 0.83 (0.74-0.92) when comparing low-risk and combined medium- and high-risk patients with HCP screening. Weighted κ analysis comparing all 3 risks groups yielded a κ (95% CI) of 0.85 (0.77-0.93) between patient and HCP screening. All patients were able to screen themselves. Overall, 96% of patients reported the MUST questionnaire as either very easy or easy to understand and to complete. Self-administered nutrition screening in outpatients with IBD is valid using the MUST screening tool and is easy to use. If adopted, this tool will increase utilization of malnutrition screening in hectic outpatient clinic settings and will help HCPs determine which patients require additional nutrition support. © 2015 American Society for Parenteral and Enteral Nutrition.

Sudbury soils study : summary of volume 3 : ecological risk assessment

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-03-15

The Sudbury soils study was comprised of 3 volumes: (1) a background, study organization and 2001 soils survey; (2) a human health risk assessment; and (3) an ecological risk assessment (ERA). This document provided details of the ERA, which was conducted to characterize the current and future risks of chemicals of concern (COC) to terrestrial and ecosystem components from Sudbury smelter particulate emissions. The extent to which COC are preventing the recovery of regionally representative terrestrial plant communities was investigated. Risks to terrestrial wildlife populations and endangered species and communities were evaluated. Samples of soil, water, sediment, plants, terrestrial invertebrates, and fish tissue were collected. Data were then analyzed by scientists and independent consultants in order to assess the impacts of arsenic, cadmium, cobalt, copper, lead, nickel and selenium. Results of the study indicated that terrestrial plant communities in the region continue to be impacted by COC in the soil, as well as by soil erosion, low nutrient levels, and a lack of soil organic matter. Direct impacts on wildlife populations were also observed. 5 refs., 7 tabs., 21 figs.

Computer/Mobile Device Screen Time of Children and Their Eye Care Behavior: The Roles of Risk Perception and Parenting.

Science.gov (United States)

Chang, Fong-Ching; Chiu, Chiung-Hui; Chen, Ping-Hung; Miao, Nae-Fang; Chiang, Jeng-Tung; Chuang, Hung-Yi

2018-03-01

This study assessed the computer/mobile device screen time and eye care behavior of children and examined the roles of risk perception and parental practices. Data were obtained from a sample of 2,454 child-parent dyads recruited from 30 primary schools in Taipei city and New Taipei city, Taiwan, in 2016. Self-administered questionnaires were collected from students and parents. Fifth-grade students spend more time on new media (computer/smartphone/tablet: 16 hours a week) than on traditional media (television: 10 hours a week). The average daily screen time (3.5 hours) for these children exceeded the American Academy of Pediatrics recommendations (≤2 hours). Multivariate analysis results showed that after controlling for demographic factors, the parents with higher levels of risk perception and parental efficacy were more likely to mediate their child's eye care behavior. Children who reported lower academic performance, who were from non-intact families, reported lower levels of risk perception of mobile device use, had parents who spent more time using computers and mobile devices, and had lower levels of parental mediation were more likely to spend more time using computers and mobile devices; whereas children who reported higher academic performance, higher levels of risk perception, and higher levels of parental mediation were more likely to engage in higher levels of eye care behavior. Risk perception by children and parental practices are associated with the amount of screen time that children regularly engage in and their level of eye care behavior.

Risk-benefit analysis for mass screening of breast cancer utilizing mammography as a screening test

International Nuclear Information System (INIS)

Iinuma, T.A.; Tateno, Yukio

1989-01-01

Incidence of breast cancers in Japanese women is increasing steadily. Mass screening of breast cancer was started in Japan under auspices of Adult Health Promotion Act of the Japanese Government from 1987. As the first screening method, the palpation of breasts is employed at present, but it is expected to be replaced by the mammography. In this report, the risk-benefit analysis is presented between risk of breast carcinogenesis due to radiation and benefit of mass screening of breast cancer. The benefit of mass screening is taken as the net elongation of average life expectancy of women due to survival from breast cancers. The risk of mammography is taken as the net loss of average life expectancy of women due to breast carcinogenesis. In the latter, the latency time and plateau period of radiation carcinogenesis were taken into consideration in the calculation. The results show that the ages at which the benefit and risk become equal are between 30 and 35 years old when dose equivalent of mammography is between 10 and 20 mSv, that are conventionally used. However, the critical age will be reduced to 20 years old if the dose equivalent becomes 1 mSv. Therefore, it is strongly recommended that a low dose mammographic system should be developed in order to achieve 1 mSv for the mass screening of breast cancer of Japanese women. In author's opinion, this is quite feasible by employing a new digital radiography with imaging plate. (author)

Prioritizing Chemicals and Data Requirements for Screening-Level Exposure and Risk Assessment

Science.gov (United States)

Brown, Trevor N.; Wania, Frank; Breivik, Knut; McLachlan, Michael S.

2012-01-01

Background: Scientists and regulatory agencies strive to identify chemicals that may cause harmful effects to humans and the environment; however, prioritization is challenging because of the large number of chemicals requiring evaluation and limited data and resources. Objectives: We aimed to prioritize chemicals for exposure and exposure potential and obtain a quantitative perspective on research needs to better address uncertainty in screening assessments. Methods: We used a multimedia mass balance model to prioritize > 12,000 organic chemicals using four far-field human exposure metrics. The propagation of variance (uncertainty) in key chemical information used as model input for calculating exposure metrics was quantified. Results: Modeled human concentrations and intake rates span approximately 17 and 15 orders of magnitude, respectively. Estimates of exposure potential using human concentrations and a unit emission rate span approximately 13 orders of magnitude, and intake fractions span 7 orders of magnitude. The actual chemical emission rate contributes the greatest variance (uncertainty) in exposure estimates. The human biotransformation half-life is the second greatest source of uncertainty in estimated concentrations. In general, biotransformation and biodegradation half-lives are greater sources of uncertainty in modeled exposure and exposure potential than chemical partition coefficients. Conclusions: Mechanistic exposure modeling is suitable for screening and prioritizing large numbers of chemicals. By including uncertainty analysis and uncertainty in chemical information in the exposure estimates, these methods can help identify and address the important sources of uncertainty in human exposure and risk assessment in a systematic manner. PMID:23008278

Prioritizing chemicals and data requirements for screening-level exposure and risk assessment.

Science.gov (United States)

Arnot, Jon A; Brown, Trevor N; Wania, Frank; Breivik, Knut; McLachlan, Michael S

2012-11-01

Scientists and regulatory agencies strive to identify chemicals that may cause harmful effects to humans and the environment; however, prioritization is challenging because of the large number of chemicals requiring evaluation and limited data and resources. We aimed to prioritize chemicals for exposure and exposure potential and obtain a quantitative perspective on research needs to better address uncertainty in screening assessments. We used a multimedia mass balance model to prioritize > 12,000 organic chemicals using four far-field human exposure metrics. The propagation of variance (uncertainty) in key chemical information used as model input for calculating exposure metrics was quantified. Modeled human concentrations and intake rates span approximately 17 and 15 orders of magnitude, respectively. Estimates of exposure potential using human concentrations and a unit emission rate span approximately 13 orders of magnitude, and intake fractions span 7 orders of magnitude. The actual chemical emission rate contributes the greatest variance (uncertainty) in exposure estimates. The human biotransformation half-life is the second greatest source of uncertainty in estimated concentrations. In general, biotransformation and biodegradation half-lives are greater sources of uncertainty in modeled exposure and exposure potential than chemical partition coefficients. Mechanistic exposure modeling is suitable for screening and prioritizing large numbers of chemicals. By including uncertainty analysis and uncertainty in chemical information in the exposure estimates, these methods can help identify and address the important sources of uncertainty in human exposure and risk assessment in a systematic manner.

Ecological Risk Assessment in Water Resource Management ...

African Journals Online (AJOL)

The US EPA published guidelines for the application of ecological risk assessment (ERA) in the USA in 1998 (US EPA 1998). The process diagram derived by Murray and Claassen (1999) in an evaluation of the US EPA framework is discussed in the context of the South African National Water Act. The evaluation discusses ...

Ecological risk assessment of toxic organic pollutant and heavy metals in water and sediment from a landscape lake in Tianjin City, China.

Science.gov (United States)

Zhang, Ying; Liu, Yuanyuan; Niu, Zhiguang; Jin, Shaopei

2017-05-01

To estimate the ecological risk of toxic organic pollutant (formaldehyde) and heavy metals (mercury (Hg), arsenic (As), cadmium (Cd), and chromium (Cr)) in water and sediment from a landscape Lake in Tianjin City, an ecological risk assessment was performed. The risk quotient (RQ) method and the AQUATOX model were used to assess the ecological risk of formaldehyde in landscape water. Meanwhile, the RQ method and the potential ecological risk index method were used to assess the ecological risk of four heavy metals in water and sediment from the studied landscape lake, respectively. The results revealed that the maximum concentration of formaldehyde in landscape water was lower than the environmental quality standards of surface water in China. The maximum simulated concentrations of formaldehyde in phytoplankton and invertebrates were 3.15 and 22.91 μg/L, respectively, which were far less than its toxicity data values (1000 and 510 μg/L, respectively), suggesting that formaldehyde in landscape water was at a safe level for aquatic organisms. The RQ model indicated that the risks of phytoplankton and invertebrates were higher than that of fish posed by Hg and Cd in landscape water, and the risks from As and Cr were acceptable for all test organisms. Cd is the most important pollution factor among all heavy metals in sediment from studied landscape lake, and the pollution factor sequence of heavy metals was Hg > As > Cr > Cd. The values of risk index (RI) for four heavy metals in samples a and b were 43.48 and 72.66, which were much lower than the threshold value (150), suggesting that the ecological risk posed by heavy metals in sediment was negligible.

Using ecological production functions to link ecological ...

Science.gov (United States)

Ecological production functions (EPFs) link ecosystems, stressors, and management actions to ecosystem services (ES) production. Although EPFs are acknowledged as being essential to improve environmental management, their use in ecological risk assessment has received relatively little attention. Ecological production functions may be defined as usable expressions (i.e., models) of the processes by which ecosystems produce ES, often including external influences on those processes. We identify key attributes of EPFs and discuss both actual and idealized examples of their use to inform decision making. Whenever possible, EPFs should estimate final, rather than intermediate, ES. Although various types of EPFs have been developed, we suggest that EPFs are more useful for decision making if they quantify ES outcomes, respond to ecosystem condition, respond to stressor levels or management scenarios, reflect ecological complexity, rely on data with broad coverage, have performed well previously, are practical to use, and are open and transparent. In an example using pesticides, we illustrate how EPFs with these attributes could enable the inclusion of ES in ecological risk assessment. The biggest challenges to ES inclusion are limited data sets that are easily adapted for use in modeling EPFs and generally poor understanding of linkages among ecological components and the processes that ultimately deliver the ES. We conclude by advocating for the incorporation into E

Baseline ecological risk assessment Salmon Site, Lamar County, Mississippi

International Nuclear Information System (INIS)

1995-04-01

The Salmon Site (SS), formerly the Tatum Dome Test Site, located in Mississippi was the site of two nuclear and two gas explosion tests conducted between 1964 and 1970. A consequence of these testing activities is that radionuclides were released into the salt dome, where they are presently contained. During reentry drilling and other site activities, incidental liquid and solid wastes that contained radioactivity were generated, resulting in some soil, ground water and equipment contamination. As part of the remedial investigation effort, a Baseline Ecological Risk Assessment was conducted at the SS. The purpose is to gauge ecological and other environmental impacts attributable to past activities at the former test facility. The results of this facility-specific baseline risk assessment are presented in this document

Baseline ecological risk assessment Salmon Site, Lamar County, Mississippi

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-04-01

The Salmon Site (SS), formerly the Tatum Dome Test Site, located in Mississippi was the site of two nuclear and two gas explosion tests conducted between 1964 and 1970. A consequence of these testing activities is that radionuclides were released into the salt dome, where they are presently contained. During reentry drilling and other site activities, incidental liquid and solid wastes that contained radioactivity were generated, resulting in some soil, ground water and equipment contamination. As part of the remedial investigation effort, a Baseline Ecological Risk Assessment was conducted at the SS. The purpose is to gauge ecological and other environmental impacts attributable to past activities at the former test facility. The results of this facility-specific baseline risk assessment are presented in this document.

A Risk Prediction Index for Advanced Colorectal Neoplasia at Screening Colonoscopy.

Science.gov (United States)

Schroy, Paul C; Wong, John B; O'Brien, Michael J; Chen, Clara A; Griffith, John L

2015-07-01

Eliciting patient preferences within the context of shared decision making has been advocated for colorectal cancer screening. Risk stratification for advanced colorectal neoplasia (ACN) might facilitate more effective shared decision making when selecting an appropriate screening option. Our objective was to develop and validate a clinical index for estimating the probability of ACN at screening colonoscopy. We conducted a cross-sectional analysis of 3,543 asymptomatic, mostly average-risk patients 50-79 years of age undergoing screening colonoscopy at two urban safety net hospitals. Predictors of ACN were identified using multiple logistic regression. Model performance was internally validated using bootstrapping methods. The final index consisted of five independent predictors of risk (age, smoking, alcohol intake, height, and a combined sex/race/ethnicity variable). Smoking was the strongest predictor (net reclassification improvement (NRI), 8.4%) and height the weakest (NRI, 1.5%). Using a simplified weighted scoring system based on 0.5 increments of the adjusted odds ratio, the risk of ACN ranged from 3.2% (95% confidence interval (CI), 2.6-3.9) for the low-risk group (score ≤2) to 8.6% (95% CI, 7.4-9.7) for the intermediate/high-risk group (score 3-11). The model had moderate to good overall discrimination (C-statistic, 0.69; 95% CI, 0.66-0.72) and good calibration (P=0.73-0.93). A simple 5-item risk index based on readily available clinical data accurately stratifies average-risk patients into low- and intermediate/high-risk categories for ACN at screening colonoscopy. Uptake into clinical practice could facilitate more effective shared decision-making for CRC screening, particularly in situations where patient and provider test preferences differ.

Suicide risk in youth with intellectual disabilities: the challenges of screening.

Science.gov (United States)

Ludi, Erica; Ballard, Elizabeth D; Greenbaum, Rachel; Pao, Maryland; Bridge, Jeffrey; Reynolds, William; Horowitz, Lisa

2012-06-01

Children and adolescents with intellectual disabilities (IDs), often diagnosed with comorbid psychiatric disorders, are a vulnerable population who may be at risk for developing suicidal thoughts and behaviors. Previous research has demonstrated that direct suicide screening can rapidly and effectively detect suicide risk and facilitate further clinical evaluation and management. Currently, there are no measures that screen for suicide risk designed specifically for individuals with ID. A review of the literature was conducted to (1) estimate the prevalence of suicidal thoughts, behaviors, and deaths by suicide in children and adolescents with ID; (2) describe associations between youth with ID and suicide risk; and (3) identify the limitations of commonly used suicide screening measures developed for non-ID youth. The literature review confirms that suicide risk exists in this population; youth with ID think about, attempt, and die by suicide. Standardized suicide risk screening is challenged by the lack of measures developed for this population. A summary of the findings is followed by a discussion of the practical clinical considerations surrounding the assessment of suicide risk in youth with ID.

Suicide Risk in Youth with Intellectual Disability: The Challenges of Screening

Science.gov (United States)

Ludi, Erica; Ballard, Elizabeth D.; Greenbaum, Rachel; Pao, Maryland; Bridge, Jeffrey; Reynolds, William; Horowitz, Lisa

2012-01-01

Children and adolescents with intellectual disabilities (ID), often diagnosed with co-morbid psychiatric disorders, are a vulnerable population who may be at risk for developing suicidal thoughts and behaviors. Previous research has demonstrated that direct suicide screening can rapidly and effectively detect suicide risk and facilitate further clinical evaluation and management. Currently, there are no measures that screen for suicide risk designed specifically for individuals with ID. A review of the literature was conducted: 1) to estimate the prevalence of suicidal thoughts, behaviors and deaths by suicide in children and adolescents with ID; 2) to describe associations between youth with ID and suicide risk; 3) to identify the limitations of commonly used suicide screening measures developed for non-ID youth. The literature review confirms that suicide risk exists in this population; youth with ID think about, attempt and die by suicide. Standardized suicide risk screening is challenged by the lack of measures developed for this population. A summary of the findings is followed by a discussion of the practical clinical considerations surrounding the assessment of suicide risk in youth with ID. PMID:22668827

Effectiveness of FISK, an invasiveness screening tool for non-native freshwater fishes, to perform risk identification assessments in the Iberian Peninsula.

Science.gov (United States)

Almeida, David; Ribeiro, Filipe; Leunda, Pedro M; Vilizzi, Lorenzo; Copp, Gordon H

2013-08-01

Risk assessments are crucial for identifying and mitigating impacts from biological invasions. The Fish Invasiveness Scoring Kit (FISK) is a risk identification (screening) tool for freshwater fishes consisting of two subject areas: biogeography/history and biology/ecology. According to the outcomes, species can be classified under particular risk categories. The aim of this study was to apply FISK to the Iberian Peninsula, a Mediterranean climate region highly important for freshwater fish conservation due to a high level of endemism. In total, 89 fish species were assessed by three independent assessors. Results from receiver operating characteristic analysis showed that FISK can discriminate reliably between noninvasive and invasive fishes for Iberia, with a threshold of 20.25, similar to those obtained in several regions around the world. Based on mean scores, no species was categorized as "low risk," 50 species as "medium risk," 17 as "moderately high risk," 11 as "high risk," and 11 as "very high risk." The highest scoring species was goldfish Carassius auratus. Mean certainty in response was above the category "mostly certain," ranging from tinfoil barb Barbonymus schwanenfeldii with the lowest certainty to eastern mosquitofish Gambusia holbrooki with the highest level. Pair-wise comparison showed significant differences between one assessor and the other two on mean certainty, with these two assessors showing a high coincidence rate for the species categorization. Overall, the results suggest that FISK is a useful and viable tool for assessing risks posed by non-native fish in the Iberian Peninsula and contributes to a "watch list" in this region. © 2013 Crown copyright This article is published with the permission of the Controller of HMSO and the Queen's Printer for Scotland.

Issuance of Final Guidance: Ecological Risk Assessment and Risk Management Principles for Superfund Sites, October 7, 1999

Science.gov (United States)

This guidance is intended to help Superfund risk managers make ecological risk management decisions that are based on sound science, consistent across Regions, and present a characterization of site risks that is transparent to the public.

The Relationship between Physical Activity and Screen Time with the Risk of Hypertension in Children and Adolescents with Intellectual Disability

Directory of Open Access Journals (Sweden)

Justyna Wyszyńska

2017-01-01

Full Text Available Introduction. Children and adolescents with intellectual disability (ID have significantly lower levels of physical activity compared to their peers without ID. Association between the level of physical activity and screen time with hypertension (HPT in children and adolescents with ID has not been reported yet. Aim. To assess the relationship between the level of physical activity and screen time with the prevalence of HPT in students with ID. Material and Methods. The study group consisted of 568 children with ID aged 7 to 18. The control group matched for age and gender consisted of 568 students without ID. Blood pressure (BP, body mass and height, level of physical activity, and screen time were assessed. Results. The level of physical activity in the study group was significantly lower than in the control group (score 1.99 versus 3.02, resp., in Physical Activity Questionnaire. The risk of HPT in the students with ID with low levels of physical activity was more than 4 times higher (OR = 4.40 and more than 2 times higher when screen time was ≥2 h/day. Conclusion. Low level of physical activity and long screen time were associated with significantly higher HPT risk among children and adolescents with ID.

Ecological models for regulatory risk assessments of pesticides: Developing a strategy for the future.

NARCIS (Netherlands)

Thorbek, P.; Forbes, V.; Heimbach, F.; Hommen, U.; Thulke, H.H.; Brink, van den P.J.

2010-01-01

Ecological Models for Regulatory Risk Assessments of Pesticides: Developing a Strategy for the Future provides a coherent, science-based view on ecological modeling for regulatory risk assessments. It discusses the benefits of modeling in the context of registrations, identifies the obstacles that

A review of metal (Pb and Zn) sensitive and pH tolerant bioassay organisms for risk screening of metal-contaminated acidic soils

International Nuclear Information System (INIS)

Chapman, E.Emily V.; Dave, Göran; Murimboh, John D.

2013-01-01

To improve risk estimates at the screening stage of Ecological Risk Assessment (ERA), short duration bioassays tailored to undisturbed soil cores from the contaminated site could be useful. However, existing standardized bioassays use disturbed soil samples and often pH sensitive organisms. This is a problem as naturally acidic soils are widespread. Changing soil properties to suit the test organism may change metal bioavailability, leading to erroneous risk estimates. For bioassays in undisturbed soil cores to be effective, species able to withstand natural soil properties must be identified. This review presents a critical examination of bioassay species' tolerance of acidic soils and sensitivity to metal contaminants such as Pb and Zn. Promising organisms include; Dendrobaena octaedra, Folsomia candida, Caenorhabditis elegans, Oppia nitens, Brassica rapa, Trifolium pratense, Allium cepa, Quercus rubra and Acer rubrum. The MetSTICK test and the Bait lamina test were also identified as suitable microorganism tests. -- Highlights: •Risk screening of metal contaminated soils should consider metal bioavailability. •Metal bioavailability is dependent on soil properties such as pH. •Many standardized bioassay organisms are sensitive to acidic soils. •This review identifies acid tolerant and metal sensitive bioassays and species. •The identified tests can improve risk screening of acidic metal contaminated soil. -- This review identifies bioassay species able to withstand naturally acidic soils while being sensitive to metal contaminants

Screening in toddlers and preschoolers at risk for autism spectrum disorder: Evaluating a novel mobile-health screening tool.

Science.gov (United States)

Kanne, Stephen M; Carpenter, Laura Arnstein; Warren, Zachary

2018-05-07

There are many available tools with varying levels of accuracy designed to screen for Autism Spectrum Disorder (ASD) in young children, both in the general population and specifically among those referred for developmental concerns. With burgeoning waitlists for comprehensive diagnostic ASD assessments, finding accurate methods and tools for advancing diagnostic triage becomes increasingly important. The current study compares the efficacy of four oft used paper and pencil measures, the Modified Checklist for Autism in Toddlers Revised with Follow-up, the Social Responsiveness Scale, Second Edition, and the Social Communication Questionnaire, and the Child Behavior Checklist to a novel mobile-health screening tool developed by Cognoa, Inc. (Cognoa) in a group of children 18-72 months of age. The Cognoa tool may have potential benefits as it integrates a series of parent-report questions with remote clinical ratings of brief video segments uploaded via parent's smartphones to calculate level of ASD risk. Participants were referred to one of three tertiary care diagnostic centers for ASD-related concerns (n = 230) and received a best estimate ASD diagnosis. Analysis and comparison of psychometric properties indicated potential advantages for Cognoa within this clinical sample across age ranges not often covered by another single measure/tool. Autism Res 2018. © 2018 International Society for Autism Research, Wiley Periodicals, Inc. With the wait times getting longer for comprehensive Autism Spectrum Disorder (ASD) diagnostic assessments, it is becoming increasingly important to find accurate tools to screen for ASD. The current study compares four screening measures that have been in use for some time to a novel mobile-health screening tool, called Cognoa. The Cognoa tool is novel because it integrates parent-report questions with clinical ratings of brief video segments uploaded via parent's smartphones to calculate ASD risk. Two hundred thirty children who

Guide for developing conceptual models for ecological risk assessments

International Nuclear Information System (INIS)

Suter, G.W., II.

1996-05-01

Ecological conceptual models are the result of the problem formulation phase of an ecological risk assessment, which is an important component of the Remedial Investigation process. They present hypotheses of how the site contaminants might affect the site ecology. The contaminant sources, routes, media, routes, and endpoint receptors are presented in the form of a flow chart. This guide is for preparing the conceptual models; use of this guide will standardize the models so that they will be of high quality, useful to the assessment process, and sufficiently consistent so that connections between sources of exposure and receptors can be extended across operable units (OU). Generic conceptual models are presented for source, aquatic integrator, groundwater integrator, and terrestrial OUs

Ecological Risk of Heavy Metals and a Metalloid in Agricultural Soils in Tarkwa, Ghana

Science.gov (United States)

Bortey-Sam, Nesta; Nakayama, Shouta M. M.; Akoto, Osei; Ikenaka, Yoshinori; Baidoo, Elvis; Mizukawa, Hazuki; Ishizuka, Mayumi

2015-01-01

Heavy metals and a metalloid in agricultural soils in 19 communities in Tarkwa were analyzed to assess the potential ecological risk. A total of 147 soil samples were collected in June, 2012 and analyzed for As, Cd, Co, Cr, Cu, Hg, Ni, Pb and Zn. Mean concentrations (mg/kg dw) of heavy metals in the communities decreased in order of Zn (39) ˃ Cr (21) ˃ Pb (7.2) ˃ Cu (6.2) ˃ As (4.4) ˃ Ni (3.7) ˃ Co (1.8) ˃ Hg (0.32) ˃ Cd (0.050). Correlations among heavy metals and soil properties indicated that soil organic matter could have substantial influence on the total contents of these metals in soil. From the results, integrated pollution (Cdeg) in some communities such as, Wangarakrom (11), Badukrom (13) and T–Tamso (17) indicated high pollution with toxic metals, especially from As and Hg. Potential ecological risk (RI) indices indicated low (Mile 7) to high risks (Wangarakrom; Badukrom) of metals. Based on pollution coefficient (Cif), Cdeg, monomial ecological risk (Eir) and RI, the investigated soils fall within low to high contamination and risk of heavy metals to the ecological system especially plants, soil invertebrates and/or mammalian wildlife. This represented moderate potential ecological risk in the study area, and mining activities have played a significant role. PMID:26378563

Landscape Ecological Risk Responses to Land Use Change in the Luanhe River Basin, China

Directory of Open Access Journals (Sweden)

Ying Li

2015-12-01

Full Text Available Land use change has large effects on natural ecosystems, which is considered to be the main factor in eco-environment change. We analyzed the future characters of land use change by the CLUE-S model and explored landscape ecological risk responses to land use change by the landscape ecological risk index method. Using the Luanhe River Basin as a case study, we simulated future land use change from 2010 to 2030 under 3 scenarios (i.e., trend, high economic growth, and ecological security, and identified the hotspots of land use change. Afterward, we quantitatively investigated the degree of land use development and landscape ecological risk patterns that have occured since 2000 and that are expected to occur until 2030. Results revealed that, under the three scenarios, construction land and forest are expanding mainly at the expense of agriculture land and grassland. The hotspots of land use change are located in the vicinity of Shuangluan and Shuangqiao District of Chengde City in the midstream of the Luanhe River Basin, where urbanization has been strong since 2000 and is projected to continue that way until 2030. During this time period, hotspots of land use development have been gradually transferring from the downstream to the midstream since 2000 and, again, is expected to continue that way until 2030, which will impact the spatial distribution of landscape ecological risk. We found that the landscape ecological risk of the entire basin has shown a negative trend. However, a few areas still have serious ecological risk, which are mainly located in the east of upstream (Duolun County and Weichang County, the middle region (Shuangluan and Shuangqiao District, Chengde County, and Xinglong County, and the downstream (Qinglong County. These can provide key information for land use management, and for helping to prepare future eco-environmental policies in the Luanhe River Basin.

[Sources, pollution statue and potential ecological risk of heavy metals in surface sediments of Aibi Lake, Northwest China].

Science.gov (United States)

Zhang, Zhao-Yong; Abuduwaili, Jilili; Jiang, Feng-Qing

2015-02-01

In this paper, the surface sediment samples were harvested from Aibi Lake, and total contents of 8 heavy metals ( Cu, Pb, Zn, As, Hg, Cr, Ni and Cd) were determined. Then the sources, pollution statue, and potential ecological risk were analyzed by using multiple analysis methods. The results show that: (1) The order of the skewness for these 8 heavy metals is: Hg > Cd > Pb > Zn > As > Cu > Cr > Ni. (2) Multivariate statistical analysis shows that 8 heavy metals can be classified to 2 principle components, among which PC1 ( Cd, Pb, Hg and Zn) is man-made source factor and mainly came from all kinds of waste of agriculture; PC2 ( Cu, Ni, Cr and As) is natural source and was mainly controlled by the background of the natural geography of this area. (3) Accumulation of index evaluation results show that the order of pollution degree values of 8 heavy metals in surface sediments of Aibi Lake is: Cd > Hg > Pb > Zn > As > Cu > Ni > Cr. In all samples, heavy metals Hg, Cd and Pb all belong to low and partial moderate pollution statue, while Zn, As, Cr, Ni and Cu belong to no pollution statue in majority samples. (4) Potential ecological risk assessment results show that the potential ecological risk of heavy metals in surface sediments of Aibi Lake mainly caused by Cd, Hg and Pb, and they accounting for 42.6%, 28.6% and 24.0% of the total amount, respectively, among which Cd is the main ecological risk factor, followed by Hg and Pb. In all samples, the potential ecological risk index values (RI) of 8 heavy metals are all lower than 150, and they are all at low ecological risk levels. However, this research also shows that there have high content of Cd and Pb in the sediment. Therefore, we should make long-term monitoring of the lake environment.

Self-reported screen time and cardiometabolic risk in obese Dutch adolescents.

Directory of Open Access Journals (Sweden)

Teatske M Altenburg

Full Text Available BACKGROUND: It is not clear whether the association between sedentary time and cardiometabolic risk exists among obese adolescents. We examined the association between screen time (TV and computer time and cardiometabolic risk in obese Dutch adolescents. METHODS AND FINDINGS: For the current cross-sectional study, baseline data of 125 Dutch overweight and obese adolescents (12-18 years participating in the Go4it study were included. Self-reported screen time (Activity Questionnaire for Adolescents and Adults and clustered and individual cardiometabolic risk (i.e. body composition, systolic and diastolic blood pressure, low-density (LDL-C, high-density (HDL-C and total cholesterol (TC, triglycerides, glucose and insulin were assessed in all participants. Multiple linear regression analyses were used to assess the association between screen time and cardiometabolic risk, adjusting for age, gender, pubertal stage, ethnicity and moderate-to-vigorous physical activity. We found no significant relationship between self-reported total screen time and clustered cardiometabolic risk or individual risk factors in overweight and obese adolescents. Unexpectedly, self-reported computer time, but not TV time, was slightly but significantly inversely associated with TC (B = -0.002; CI = [-0.003;-0.000] and LDL-C (B = -0.002; CI = [-0.001;0.000]. CONCLUSIONS: In obese adolescents we could not confirm the hypothesised positive association between screen time and cardiometabolic risk. Future studies should consider computer use as a separate class of screen behaviour, thereby also discriminating between active video gaming and other computer activities.

Knowledge, attitude and practice for breast cancer risk factors and screening modalities in staff nurses of Ayub teaching hospital Abbottabad

International Nuclear Information System (INIS)

Ahmad, S.; Riaz, A.; Rizwan, M.; Qureshi, N.A.; Atta, S.

2012-01-01

Background: Breast cancer is the commonest cancer modality in female worldwide. Avoiding the risk factors can reduce its incidence and adhering to screening and early detection can reduce its mortality. A sufficient knowledge regarding the risk factors and screening modalities is therefore essential. We assessed the knowledge level about these parameters in our staff nurses. Methods: A self-administered questionnaire survey was performed. Knowledge regarding the risk factors and screening modalities were categorised into good, fair, poor and very poor categories. Results: Knowledge regarding most of the factors was found to be fair. A few things were termed as good knowledge like role of breast-feeding in protecting against breast cancer. Practice regarding the screening modalities was not satisfactory. Only a few nurses had good knowledge of the risk factors and screening modalities. Practice of the Screening modalities was also poor. Conclusion: There is a need to improve the nursing curriculum, training at the workplace and motivate them for screening practices. They should be encouraged to talk to their patients and their female attendants about prevention and early detection of breast cancer. (author)

Screening for markers of frailty and perceived risk of adverse outcomes using the Risk Instrument for Screening in the Community (RISC).

LENUS (Irish Health Repository)

O Caoimh, Rónán

2014-09-19

Functional decline and frailty are common in community dwelling older adults, increasing the risk of adverse outcomes. Given this, we investigated the prevalence of frailty-associated risk factors and their distribution according to the severity of perceived risk in a cohort of community dwelling older adults, using the Risk Instrument for Screening in the Community (RISC).

Ecological risk assessment of cheese whey effluents along a medium-sized river in southwest Greece.

Science.gov (United States)

Karadima, Constantina; Theodoropoulos, Chris; Rouvalis, Angela; Iliopoulou-Georgudaki, Joan

2010-01-01

An ecological risk assessment of cheese whey effluents was applied in three critical sampling sites located in Vouraikos river (southwest Greece), while ecological classification using Water Framework Directive 2000/60/EU criteria allowed a direct comparison of toxicological and ecological data. Two invertebrates (Daphnia magna and Thamnocephalus platyurus) and the zebra fish Danio rerio were used for toxicological analyses, while the aquatic risk was calculated on the basis of the risk quotient (RQ = PEC/PNEC). Chemical classification of sites was carried out using the Nutrient Classification System, while benthic invertebrates were collected and analyzed for biological classification. Toxicological results revealed the heavy pollution load of the two sites, nearest to the point pollution source, as the PEC/PNEC ratio exceeded 1.0, while unexpectedly, no risk was detected for the most downstream site, due to the consequent interference of the riparian flora. These toxicological results were in agreement with the ecological analysis: the ecological quality of the two heavily impacted sites ranged from moderate to bad, whereas it was found good for the most downstream site. The results of the study indicate major ecological risk for almost 15 km downstream of the point pollution source and the potentiality of the water quality remediation by the riparian vegetation, proving the significance of its maintenance.

Risk Factors for Incident Diabetic Polyneuropathy in a Cohort With Screen-Detected Type 2 Diabetes Followed for 13 Years

DEFF Research Database (Denmark)

Andersen, Signe T; Witte, Daniel R; Dalsgaard, Else-Marie

2018-01-01

OBJECTIVE: To study incident diabetic polyneuropathy (DPN) prospectively during the first 13 years after a screening-based diagnosis of type 2 diabetes and determine the associated risk factors for the development of DPN. RESEARCH DESIGN AND METHODS: We assessed DPN longitudinally in the Danish arm...... of the Anglo-Danish-Dutch study of Intensive Treatment of Diabetes in Primary Care (ADDITION) using the Michigan Neuropathy Screening Instrument questionnaire (MNSIQ), defining DPN with scores ≥4. Risk factors present at the diabetes diagnosis associated with the risk of incident DPN were estimated using Cox...... DPN. CONCLUSIONS: This study provides further epidemiological evidence for obesity as a risk factor for DPN. Moreover, low HDL cholesterol levels and higher levels of methylglyoxal, a marker of dicarbonyl stress, are identified as risk factors for the development of DPN....

Cost effectiveness of risk-based closures at UST sites

International Nuclear Information System (INIS)

Scruton, K.M.; Baker, J.N.

1995-01-01

Risk-based closures have been achieved at Underground Storage Tank (UST) sites throughout the country for a major transportation company. The risk-based closures were cost-effective because a streamlined risk-based approach was used instead of the generic baseline risk assessment approach. USEPA has recently provided guidance encouraging the use of risk-based methodology for achieving closure at UST sites. The risk-based approach used in achieving the site closures involved an identification of potential human and ecological receptors and exposure pathways, and a comparison of maximum onsite chemical concentrations to applicable or relevant and appropriate requirements (ARARs). The ARARs used in the evaluation included Federal and/or State Maximum Contaminant Levels (MCLs) for groundwater and risk-based screening levels for soils. If the maximum concentrations were above the screening levels, a baseline risk assessment was recommended. In several instances, however, the risk-based approach resulted in a regulatory agency acceptance of a ''no further action'' alternative at UST sites which did not pose a significant threat to human health and the environment. The cost of the streamlined risk-based approach is approximately $3,500, while a baseline risk assessment for the same UST site could cost up to $10,000 or more. The use of the streamlined risk-based approach has proven to be successful for achieving a ''no further action'' outcome for the client at a reasonable cost

A method for calculating effective lifetime risk of radiation-induced cancer from screening mammography

International Nuclear Information System (INIS)

Ali, R.M.; England, A.; McEntee, M.F.; Hogg, P.

2015-01-01

Purpose: To propose a method for evaluating the effective lifetime risk of radiation-induced cancer from screening mammography and to present initial data for the UK National Breast Screening Programme. Material and methods: The imaging was undertaken using a Hologic Selenia full field digital mammographic unit. The proposed method utilises an ATOM phantom containing thermoluminescent dosimeters and a perspex-polyethylene breast phantom to measure organ doses during a standard four view screening mammogram. Effective dose was calculated and effective risk was modelled for a range of client ages. The total lifetime effective risk was then calculated for the UK national screening programme. Calculation of effective risk includes the radiation dose to examined and contralateral breasts in addition to other body organs; this is an advantage over the mean glandular dose. Results: The contralateral breast, thyroid, thymus, brain, lung, salivary glands, and bone marrow all receive more than 1 μGy radiation dose during screening mammography. A major difference exists for total effective lifetime risk of radiation-induced cancer between clients with average and high breast cancer risk. Differences are attributed to the commencement age of screening and time interval between screens. Conclusion: This study proposes a method to evaluate effective lifetime risk of radiation-induced cancer from screening mammography in order to compare different mammography screening programmes. - Highlights: • We proposed a method for the calculation of radiation-induced cancer from screening mammography. • We measured the radiation absorbed dose of different organs during screening mammography. • There are major differences between mammography screening programme categories with regard to radiation effective risk.

The role of ecological models in linking ecological risk assessment to ecosystem services in agroecosystems

NARCIS (Netherlands)

Galic, N.G.; Schmolke, A.; Forbes, V.; Baveco, J.M.; Brink, van den P.J.

2012-01-01

Agricultural practices are essential for sustaining the human population, but at the same time they can directly disrupt ecosystem functioning. Ecological risk assessment (ERA) aims to estimate possible adverse effects of human activities on ecosystems and their parts. Current ERA practices,

[Ecological risk assessment of land use based on exploratory spatial data analysis (ESDA): a case study of Haitan Island, Fujian Province].

Science.gov (United States)

Wu, Jian; Chen, Peng; Wen, Chao-Xiang; Fu, Shi-Feng; Chen, Qing-Hui

2014-07-01

As a novel environment management tool, ecological risk assessment has provided a new perspective for the quantitative evaluation of ecological effects of land-use change. In this study, Haitan Island in Fujian Province was taken as a case. Based on the Landsat TM obtained in 1990, SPOT5 RS images obtained in 2010, general layout planning map of Pingtan Comprehensive Experimental Zone in 2030, as well as the field investigation data, we established an ecological risk index to measure ecological endpoints. By using spatial autocorrelation and semivariance analysis of Exploratory Spatial Data Analysis (ESDA), the ecological risk of Haitan Island under different land-use situations was assessed, including the past (1990), present (2010) and future (2030), and the potential risk and its changing trend were analyzed. The results revealed that the ecological risk index showed obvious scale effect, with strong positive correlation within 3000 meters. High-high (HH) and low-low (LL) aggregations were predominant types in spatial distribution of ecological risk index. The ecological risk index showed significant isotropic characteristics, and its spatial distribution was consistent with Anselin Local Moran I (LISA) distribution during the same period. Dramatic spatial distribution change of each ecological risk area was found among 1990, 2010 and 2030, and the fluctuation trend and amplitude of different ecological risk areas were diverse. The low ecological risk area showed a rise-to-fall trend while the medium and high ecological risk areas showed a fall-to-rise trend. In the planning period, due to intensive anthropogenic disturbance, the high ecological risk area spread throughout the whole region. To reduce the ecological risk in land-use and maintain the regional ecological security, the following ecological risk control strategies could be adopted, i.e., optimizing the spatial pattern of land resources, protecting the key ecoregions and controlling the scale of

Dynamic Ecological Risk Assessment and Management of Land Use in the Middle Reaches of the Heihe River Based on Landscape Patterns and Spatial Statistics

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Jiahui Fan

2016-06-01

Full Text Available Land use profoundly changes the terrestrial ecosystem and landscape patterns, and these changes reveal the extent and scope of the ecological influence of land use on the terrestrial ecosystem. The study area selected for this research was the middle reaches of the Heihe River. Based on land use data (1986, 2000, and 2014, we proposed an ecological risk index of land use by combining a landscape disturbance index with a landscape fragility index. An exponential model was selected to perform kriging interpolation, as well as spatial autocorrelations and semivariance analyses which could reveal the spatial aggregation patterns. The results indicated that the ecological risk of the middle reaches of the Heihe River was generally high, and higher in the northwest. The high values of the ecological risk index (ERI tended to decrease, and the low ERI values tended to increase. Positive spatial autocorrelations and a prominent scale-dependence were observed among the ERI values. The main hot areas with High-High local autocorrelations were located in the north, and the cold areas with low-low local autocorrelations were primarily located in the middle corridor plain and Qilian Mountains. From 1986 to 2014, low and relatively low ecological risk areas decreased while relatively high risk areas expanded. A middle level of ecological risk was observed in Ganzhou and Minle counties. Shandan County presented a serious polarization, with high ecological risk areas observed in the north and low ecological risk areas observed in the southern Shandan horse farm. In order to lower the eco-risk and achieve the sustainability of land use, these results suggest policies to strictly control the oasis expansion and the occupation of farmland for urbanization. Some inefficient farmland should transform into grassland in appropriate cases.

Service Use by At-Risk Youth after School-Based Suicide Screening

Science.gov (United States)

2009-01-01

Objective We sought to examine follow-up service use by students identified at risk for suicidal behavior in a school-based screening program, and assess barriers to seeking services as perceived by youth and parents. Method We conducted a longitudinal study of 317 at-risk youth identified by a school-based suicide screening in six high schools in New York State. The at-risk teenagers and their parents were interviewed approximately two years after the initial screen to assess service use during the intervening period and identify barriers that may have interfered with seeking treatment. Results At the time of the screen, 72% of the at-risk students were not receiving any type of mental health service. Of these students, 51% were deemed in need of services and subsequently referred by us to a mental health professional. Nearly 70% followed through with the screening’s referral recommendations. Youth and their parents reported perceptions about mental health problems, specifically relating to the need for treatment, as the primary reasons for not seeking service. Conclusions Screening appears to be effective in enhancing the likelihood that students at risk for suicidal behavior will get into treatment. Well developed and systematic planning is needed to ensure that screening and referral services are coordinated so as to facilitate access for youth into timely treatment. PMID:19858758

Elder Abuse by Adult Children: An Applied Ecological Framework for Understanding Contextual Risk Factors and the Intergenerational Character of Quality of Life.

Science.gov (United States)

Schiamberg, Lawrence B.; Gans, Daphna

2000-01-01

Using an applied ecological model, this study focuses on contextual risk factors of elder abuse. Five levels of environment were used to interpret existing research on risk factors. Configuration of risk factors provides a framework for understanding the intergenerational character of quality of life for older adults, developing recommendations…

Phase two of Site 300's ecological risk assessment: Model verification and risk management

International Nuclear Information System (INIS)

Carlson, T.M.; Gregory, S.D.

1995-01-01

The authors completed the baseline ecological risk assessment (ERA) for Lawrence Livermore National Laboratory's Site 300 in 1993. Using data collection and modeling techniques adapted from the human health risk assessment (HRA), they evaluated the potential hazard of contaminants in environmental media to ecological receptors. They identified potential hazards to (1) aquatic invertebrates from heavy metal contaminants in surface water, (2) burrowing vertebrates from contaminants volatilizing from subsurface soil into burrow air, and (3) grazing deer and burrowing vertebrates from cadmium contamination in surface soil. They recently began collecting data to refine the estimates of potential hazard to these ecological receptors. Bioassay results form the surface water failed to verify a hazard to aquatic invertebrates. Soil vapor surveys of subsurface burrows did verify the presence of high concentrations of volatile organic compounds (VOCs). However, they have not yet verified a true impact on the burrowing populations. The authors also completed an extensive surface soil sampling program, which identified local hot spots of cadmium contamination. In addition, they have been collecting data on the land use patterns of the deer population. Their data indicate that deer do not typically use those areas with cadmium surface soil contamination. Information from this phase of the ERA, along with the results of the HRA, will direct the selection of remedial alternatives for the site. For the ecological receptors, remedial alternatives include developing a risk management program which includes ensuring that (1) sensitive burrowing species (such as rare or endangered species) do not use areas of surface or subsurface contamination, and (2) deer populations do not use areas of surface soil contamination

Terrestrial population models for ecological risk assessment: A state-of-the-art review

Science.gov (United States)

Emlen, J.M.

1989-01-01

Few attempts have been made to formulate models for predicting impacts of xenobiotic chemicals on wildlife populations. However, considerable effort has been invested in wildlife optimal exploitation models. Because death from intoxication has a similar effect on population dynamics as death by harvesting, these management models are applicable to ecological risk assessment. An underlying Leslie-matrix bookkeeping formulation is widely applicable to vertebrate wildlife populations. Unfortunately, however, the various submodels that track birth, death, and dispersal rates as functions of the physical, chemical, and biotic environment are by their nature almost inevitably highly species- and locale-specific. Short-term prediction of one-time chemical applications requires only information on mortality before and after contamination. In such cases a simple matrix formulation may be adequate for risk assessment. But generally, risk must be projected over periods of a generation or more. This precludes generic protocols for risk assessment and also the ready and inexpensive predictions of a chemical's influence on a given population. When designing and applying models for ecological risk assessment at the population level, the endpoints (output) of concern must be carefully and rigorously defined. The most easily accessible and appropriate endpoints are (1) pseudoextinction (the frequency or probability of a population falling below a prespecified density), and (2) temporal mean population density. Spatial and temporal extent of predicted changes must be clearly specified a priori to avoid apparent contradictions and confusion.

State-level differences in breast and cervical cancer screening by disability status: United States, 2008.

Science.gov (United States)

Armour, Brian S; Thierry, JoAnn M; Wolf, Lesley A

2009-01-01

Despite reported disparities in the use of preventive services by disability status, there has been no national surveillance of breast and cervical cancer screening among women with disabilities in the United States. To address this, we used state-level surveillance data to identify disparities in breast and cervical cancer screening among women by disability status. Data from the 2008 Behavioral Risk Factor Surveillance System were used to estimate disability prevalence and state-level differences in breast and cervical cancer screening among women by disability status. Overall, modest differences in breast cancer screening were found; women with a disability were less likely than those without to report receiving a mammogram during the past 2 years (72.2% vs. 77.8%; p < .001). However, disparities in breast cancer screening were more pronounced at the state level. Furthermore, women with a disability were less likely than those without a disability to report receiving a Pap test during the past 3 years (78.9% vs. 83.4%; p < .001). This epidemiologic evidence identifies an opportunity for federal and state programs, as well as other stakeholders, to form partnerships to align disability and women's health policies. Furthermore, it identifies the need for increased public awareness and resource allocation to reduce barriers to breast and cervical cancer screening experienced by women with disabilities.

Ecological risk assessment: influence of texture on background concentration of microelements in soils of Russia.

Science.gov (United States)

Beketskaya, Olga

2010-05-01

In Russia quality standards of contaminated substances values in environment consist of ecological and sanitary rate-setting. The sanitary risk assessment base on potential risk that contaminants pose to protect human beings. The main purpose of the ecological risk assessment is to protect ecosystem. To determine negative influence on living organisms in the sanitary risk assessment in Russia we use MPC. This value of contaminants show how substances affected on different part of environment, biological activity and soil processes. The ecological risk assessment based on comparison compounds concentration with background concentration for definite territories. Taking into account high interval of microelements value in soils, we suggest using statistic method for determination of concentration levels of chemical elements concentration in soils of Russia. This method is based on determination middle levels of elements content in natural condition. The top limit of middle chemical elements concentration in soils is value, which exceed middle regional background level in three times standard deviation. The top limit of natural concentration excess we can explain as anthropogenic impact. At first we study changing in the middle content value of microelements in soils of geographic regions in European part of Russia on the basis of cartographical analysis. Cartographical analysis showed that the soil of mountainous and mountain surrounding regions is enriched with microelements. On the plain territory of European part of Russia for most of microelements was noticed general direction of increasing their concentration in soils from north to south, also in the same direction soil clay content rise for majority of soils. For all other territories a clear connection has been noticed between the distribution of sand sediment. By our own investigation and data from scientific literature data base was created. This data base consist of following soil properties: texture

Screening for breast cancer in a high-risk series

International Nuclear Information System (INIS)

Woodard, E.D.; Hempelmann, L.H.; Janus, J.; Logan, W.; Dean, P.

1982-01-01

A unique cohort of women at increased risk of breast cancer because of prior X-ray treatment of acute mastitis and their selected high-risk siblings were offered periodic breast cancer screening including physical examination of the breasts, mammography, and thermography. Twelve breast cancers were detected when fewer than four would have been expected based on age-specific breast cancer detection rates from the National Cancer institute/American Cancer Society Breast Cancer Demonstration Detection Projects. Mammograpy was positive in all cases but physical examination was positive in only three cases. Thermography was an unreliable indicator of disease. Given the concern over radiation-induced risk, use of low-dose technique and of criteria for participation that select women at high risk of breast cancer will maximize the benefit/risk ratio for mammography screening

Web-enabling Ecological Risk Assessment for Accessibility and Transparency

Science.gov (United States)

Ecological risk methods and tools are necessarily diverse to account for different combinations of receptors, exposure processes, effects estimation, and degree of conservatism/realism necessary to support chemical-based assessments. These tools have been continuously developed s...

Community-Based Diabetes Screening and Risk Assessment in Rural West Virginia

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Ranjita Misra

2016-01-01

Full Text Available This project utilized a cross-sectional study design to assess diabetes risk among 540 individuals from 12 counties using trained extension agents and community organizations in West Virginia. Individuals were screened for diabetes using (1 the validated 7-item diabetes risk assessment survey and (2 hemoglobin A1c tests. Demographic and lifestyle behaviors were also collected. The average age, body mass index, and A1c were 51.2±16.4, 31.1±7.5, and 5.8±0.74, respectively. The majority were females, Non-Hispanic Whites with no prior diagnosis of diabetes. Screenings showed that 61.8% of participants were at high risk for diabetes. Family history of diabetes (siblings or parents, overweight or obese status, sedentary lifestyle, and older age were commonly prevalent risk factors. Higher risk scores computed from the 7-item questions correlated positively with higher A1c (r=0.221, P<0.001. In multivariate logistic regression analyses, higher diabetes risk was predicted by obesity, older age, family history of hypertension, and gestational diabetes. Females were 4 times at higher risk than males. The findings indicated that community-based screenings were an effective way to assess diabetes risk in rural West Virginia. Linking diabetes screenings with referrals to lifestyle programs for high risk individuals can help reduce the burden of diabetes in the state.

Risk assessment and clinical decision making for colorectal cancer screening.

Science.gov (United States)

Schroy, Paul C; Caron, Sarah E; Sherman, Bonnie J; Heeren, Timothy C; Battaglia, Tracy A

2015-10-01

Shared decision making (SDM) related to test preference has been advocated as a potentially effective strategy for increasing adherence to colorectal cancer (CRC) screening, yet primary care providers (PCPs) are often reluctant to comply with patient preferences if they differ from their own. Risk stratification advanced colorectal neoplasia (ACN) provides a rational strategy for reconciling these differences. To assess the importance of risk stratification in PCP decision making related to test preference for average-risk patients and receptivity to use of an electronic risk assessment tool for ACN to facilitate SDM. Mixed methods, including qualitative key informant interviews and a cross-sectional survey. PCPs at an urban, academic safety-net institution. Screening preferences, factors influencing patient recommendations and receptivity to use of a risk stratification tool. Nine PCPs participated in interviews and 57 completed the survey. Despite an overwhelming preference for colonoscopy by 95% of respondents, patient risk (67%) and patient preferences (63%) were more influential in their decision making than patient comorbidities (31%; P decision making, yet few providers considered risk factors other than age for average-risk patients. Providers were receptive to the use of a risk assessment tool for ACN when recommending an appropriate screening test for select patients. © 2013 John Wiley & Sons Ltd.

Can a Risk Factor Based Approach Safely Reduce Screening for Retinopathy of Prematurity?

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K. M. Friddle

2017-01-01

Full Text Available Objective. Current American retinopathy of prematurity (ROP screening guidelines is imprecise for infants ≥ 30 weeks with birth weights between 1500 and 2000 g. Our objective was to evaluate a risk factor based approach for screening premature infants at low risk for severe ROP. Study Design. We performed a 13-year review from Intermountain Health Care (IHC data. All neonates born at ≤32 weeks were reviewed to determine ROP screening and/or development of severe ROP. Severe ROP was defined by stage ≥ 3 or need for laser therapy. Regression analysis was used to identify significant risk factors for severe ROP. Results. We identified 4607 neonates ≤ 32 weeks gestation. Following exclusion for death, with no retinal exam or incomplete data, 2791 (61% were included in the study. Overall, severe ROP occurred in 260 (9.3%, but only 11/1601 ≥ 29 weeks (0.7%. All infants with severe ROP ≥ 29 weeks had at least 2 identified ROP risk factors. Implementation of this risk based screening strategy to the IHC population over the timeline of this study would have eliminated screening in 21% (343/1601 of the screened population. Conclusions. Limiting ROP screening for infants ≥ 29 and ≤ 32 weeks to only those with clinical risk factors could significantly reduce screening exams while identifying all infants with severe ROP.

Can data science inform environmental justice and community risk screening for type 2 diabetes?

Science.gov (United States)

Davis, J Allen; Burgoon, Lyle D

2015-01-01

Having the ability to scan the entire country for potential "hotspots" with increased risk of developing chronic diseases due to various environmental, demographic, and genetic susceptibility factors may inform risk management decisions and enable better environmental public health policies. Develop an approach for community-level risk screening focused on identifying potential genetic susceptibility hotpots. Our approach combines analyses of phenotype-genotype data, genetic prevalence of single nucleotide polymorphisms, and census/geographic information to estimate census tract-level population attributable risks among various ethnicities and total population for the state of California. We estimate that the rs13266634 single nucleotide polymorphism, a type 2 diabetes susceptibility genotype, has a genetic prevalence of 56.3%, 47.4% and 37.0% in Mexican Mestizo, Caucasian, and Asian populations. Looking at the top quintile for total population attributable risk, 16 California counties have greater than 25% of their population living in hotspots of genetic susceptibility for developing type 2 diabetes due to this single genotypic susceptibility factor. This study identified counties in California where large portions of the population may bear additional type 2 diabetes risk due to increased genetic prevalence of a susceptibility genotype. This type of screening can easily be extended to include information on environmental contaminants of interest and other related diseases, and potentially enables the rapid identification of potential environmental justice communities. Other potential uses of this approach include problem formulation in support of risk assessments, land use planning, and prioritization of site cleanup and remediation actions.

Confusing Relative Risk with Absolute Risk Is Associated with More Enthusiastic Beliefs about the Value of Cancer Screening.

Science.gov (United States)

Caverly, Tanner J; Prochazka, Allan V; Binswanger, Ingrid A; Kutner, Jean S; Matlock, Daniel D

2014-07-01

Reviews of how data are presented in medical literature document that the benefit from an intervention is often exaggerated relative to the harm (e.g., relative risk for benefit and absolute risk for harm). Such mismatched presentations may create unwarranted enthusiasm, especially among those who misinterpret the statistics presented. The objective was to determine whether misinterpretation of risk data predicts enthusiasm for cancer screening. The authors administered a survey with 14 items assessing beliefs about cancer screening and 6 items measuring data interpretation ability. Multiple linear regression was used to evaluate the association between data interpretation and enthusiasm for cancer screening, with adjustment for gender and year graduated from medical school. Eighty-eight of 139 physicians at a state-wide professional meeting returned completed surveys (63% response rate). Lower data interpretation scores were associated with higher enthusiasm for cancer screening scores (P = 0.004) in the adjusted primary analysis. Confusing relative risk with absolute risk appeared to drive the overall association. Biased presentations of risk data could affect general beliefs about the value of cancer screening, especially among physicians who uncritically accept mismatched presentations of data. © The Author(s) 2014.

The quality of risk factor screening during antenatal consultations in Niger.

Science.gov (United States)

Prual, A; Toure, A; Huguet, D; Laurent, Y

2000-03-01

A decade after the first International Conference on Safe Motherhood, maternal mortality remains very high in most West African countries, even in capital cities. The detection of high risk pregnancies, known as the risk approach, during antenatal consultations has been the basis of most maternal and child health programmes over the last decade. The effectiveness of antenatal care as a tool to prevent or predict obstetric complications is being questioned more and more. In addition to the scarcity of reliable data about the predictivity of most risk factors, the quality of the screening must be questioned. The goal of this study was to assess the frequency of risk factors among a sample of pregnant women attending antenatal care in Niger and to assess the quality of the screening of those risk factors. Overall, 330 pregnant women were enrolled in the study. Each woman was examined twice: the first time by a midwife, the second time by one of the authors but without knowledge of the results of the first consultation. Fifty-five percent of pregnant women had at least one risk factor, 31% had more than one. Ninety-one percent of the risk factors were detected at interview. The following risk factors were not systematically searched for by midwives: height (48.5%), blood pressure (43.6%), glycosuria (40.6%), vaginal bleeding (38.2%), oedema (37.3%), parity (17%), age (16%), previous caesarean section (15.2%), previous stillbirth (15.2%) and previous miscarriages (14.8%). This study has shown that, in Niger, the quality of screening for risk factors during antenatal consultation is poor. In the urban settings where this study took place, lack of personnel, lack of equipment, lack of time and poor compliance by women cannot be made responsible for this situation. While screening of these risk factors continues as policy, the quality of screening must be dramatically improved.

Harmful Chemicals in Soil and Risk Assessment of an Abandoned Open Dumpsite in Eastern China

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Ying Huang

2015-01-01

Full Text Available The concentrations of pollutants in soil samples collected in and around a dumpsite in Heze, Shandong, China, were investigated, and the potential ecological and health risks of these pollutants were assessed. Seventeen soil samples from five different locations were analysed for pollution characteristics, and the target pollutants included inorganic pollutants and heavy metals as well as volatile organic compounds/semivolatile organic compounds (VOCs/SVOCs. Results showed that the mean concentration level of each pollutant from the interior area was relatively higher than that from the boundary area of the dumpsite. Inorganic pollutants and heavy metals were detected in all of the soil samples. According to potential ecological risk assessment with environmental background values of Shandong as screening values, heavy metals in majority of the samples pose low ecological risk to the ecosystem except Hg. Hg poses a considerable or very high risk because of its high levels of accumulation. In consideration of future land use pattern, human health risks derived from environmental exposure to heavy metals were assessed. Carcinogenic risk and noncarcinogenic hazards for adults are acceptable, while noncarcinogenic hazards for children exceed the safety threshold. The health risks are primarily attributed to oral exposure to As and Cr.

The pollution and the potential ecological risk of heavy metals in swan lake wetland of Sanmenxia

Science.gov (United States)

Li, Jifeng

2018-04-01

The soil samples were collected from swanlake wetland and digested by the national standard method. The contents of Pb, Cr, Cu, Zn and Mn were detected and the potential ecological risk was estimated by the the potential ecological risk index. The result shows the wetland was slightly ecological hazarded. The ecosystem has been affected by the heavy metal.

Predicting Sport and Occupational Lower Extremity Injury Risk through Movement Quality Screening: A Systematic Review

Science.gov (United States)

Whittaker, Jackie L; Booysen, Nadine; de la Motte, Sarah; Dennett, Liz; Lewis, Cara L.; Wilson, Dave; McKay, Carly; Warner, Martin; Padua, Darin; Emery, Carolyn A; Stokes, Maria

2017-01-01

Background Identification of risk factors for lower extremity (LE) injury in sport and military/first-responder occupations is required to inform injury prevention strategies. Objective To determine if poor movement quality is associated with LE injury in sport and military/first-responder occupations. Material and methods Five electronic databases were systematically searched. Studies selected included: original data; analytic design; movement quality outcome (qualitative rating of functional compensation, asymmetry, impairment or efficiency of movement control); LE injury sustained with sport or military/first-responder occupation. The PRISMA guidelines were followed. Two independent authors assessed the quality [Downs and Black (DB) criteria] and level of evidence (Oxford Centre of Evidence-Based Medicine model). Results Of 4361 potential studies, 17 were included. The majority were low quality cohort studies (level 4 evidence). Median DB score was 11/33 (range 3–15). Heterogeneity in methodology and injury definition precluded meta-analyses. The Functional Movement Screen was the most common outcome investigated (15/17 studies). Four studies considered interrelationships between risk factors, seven reported diagnostic accuracy and none tested an intervention program targeting individuals identified as high-risk. There is inconsistent evidence that poor movement quality is associated with increased risk of LE injury in sport and military/first-responder occupations. Conclusions Future research should focus on high quality cohort studies to identify the most relevant movement quality outcomes for predicting injury risk followed by developing and evaluating pre-participation screening and LE injury prevention programs through high quality randomized controlled trials targeting individuals at greater risk of injury based upon screening tests with validated test properties. PMID:27935483

Potential ecological risk assessment and predicting zinc accumulation in soils.

Science.gov (United States)

Baran, Agnieszka; Wieczorek, Jerzy; Mazurek, Ryszard; Urbański, Krzysztof; Klimkowicz-Pawlas, Agnieszka

2018-02-01

The aims of this study were to investigate zinc content in the studied soils; evaluate the efficiency of geostatistics in presenting spatial variability of zinc in the soils; assess bioavailable forms of zinc in the soils and to assess soil-zinc binding ability; and to estimate the potential ecological risk of zinc in soils. The study was conducted in southern Poland, in the Malopolska Province. This area is characterized by a great diversity of geological structures and types of land use and intensity of industrial development. The zinc content was affected by soil factors, and the type of land use (arable lands, grasslands, forests, wastelands). A total of 320 soil samples were characterized in terms of physicochemical properties (texture, pH, organic C content, total and available Zn content). Based on the obtained data, assessment of the ecological risk of zinc was conducted using two methods: potential ecological risk index and hazard quotient. Total Zn content in the soils ranged from 8.27 to 7221 mg kg -1 d.m. Based on the surface semivariograms, the highest variability of zinc in the soils was observed from northwest to southeast. The point sources of Zn contamination were located in the northwestern part of the area, near the mining-metallurgical activity involving processing of zinc and lead ores. These findings were confirmed by the arrangement of semivariogram surfaces and bivariate Moran's correlation coefficients. The content of bioavailable forms of zinc was between 0.05 and 46.19 mg kg -1 d.m. (0.01 mol dm -3 CaCl 2 ), and between 0.03 and 71.54 mg kg -1 d.m. (1 mol dm -3 NH 4 NO 3 ). Forest soils had the highest zinc solubility, followed by arable land, grassland and wasteland. PCA showed that organic C was the key factor to control bioavailability of zinc in the soils. The extreme, very high and medium zinc accumulation was found in 69% of studied soils. There is no ecological risk of zinc to living organisms in the study area, and in 90

Mesocosm soil ecological risk assessment tool for GMO 2nd tier studies

DEFF Research Database (Denmark)

D'Annibale, Alessandra; Maraldo, Kristine; Larsen, Thomas

Ecological Risk Assessment (ERA) of GMO is basically identical to ERA of chemical substances, when it comes to assessing specific effects of the GMO plant material on the soil ecosystem. The tiered approach always includes the option of studying more complex but still realistic ecosystem level...... effects in 2nd tier caged experimental systems, cf. the new GMO ERA guidance: EFSA Journal 2010; 8(11):1879. We propose to perform a trophic structure analysis, TSA, and include the trophic structure as an ecological endpoint to gain more direct insight into the change in interactions between species, i.......e. the food-web structure, instead of relying only on the indirect evidence from population abundances. The approach was applied for effect assessment in the agro-ecosystem where we combined factors of elevated CO2, viz. global climate change, and GMO plant effects. A multi-species (Collembola, Acari...

Ecological risk of anthropogenic pollutants to reptiles: Evaluating assumptions of sensitivity and exposure

International Nuclear Information System (INIS)

Weir, Scott M.; Suski, Jamie G.; Salice, Christopher J.

2010-01-01

A large data gap for reptile ecotoxicology still persists; therefore, ecological risk assessments of reptiles usually incorporate the use of surrogate species. This necessitates that (1) the surrogate is at least as sensitive as the target taxon and/or (2) exposures to the surrogate are greater than that of the target taxon. We evaluated these assumptions for the use of birds as surrogates for reptiles. Based on a survey of the literature, birds were more sensitive than reptiles in less than 1/4 of the chemicals investigated. Dietary and dermal exposure modeling indicated that exposure to reptiles was relatively high, particularly when the dermal route was considered. We conclude that caution is warranted in the use of avian receptors as surrogates for reptiles in ecological risk assessment and emphasize the need to better understand the magnitude and mechanism of contaminant exposure in reptiles to improve exposure and risk estimation. - Avian receptors are not universally appropriate surrogates for reptiles in ecological risk assessment.

Ecological risk of anthropogenic pollutants to reptiles: Evaluating assumptions of sensitivity and exposure

Energy Technology Data Exchange (ETDEWEB)

Weir, Scott M., E-mail: scott.weir@ttu.ed [Texas Tech University, Institute of Environmental and Human Health, Department of Environmental Toxicology, Box 41163, Lubbock, TX (United States); Suski, Jamie G., E-mail: jamie.suski@ttu.ed [Texas Tech University, Department of Biological Sciences, Box 43131, Lubbock, TX (United States); Salice, Christopher J., E-mail: chris.salice@ttu.ed [Texas Tech University, Institute of Environmental and Human Health, Department of Environmental Toxicology, Box 41163, Lubbock, TX (United States)

2010-12-15

A large data gap for reptile ecotoxicology still persists; therefore, ecological risk assessments of reptiles usually incorporate the use of surrogate species. This necessitates that (1) the surrogate is at least as sensitive as the target taxon and/or (2) exposures to the surrogate are greater than that of the target taxon. We evaluated these assumptions for the use of birds as surrogates for reptiles. Based on a survey of the literature, birds were more sensitive than reptiles in less than 1/4 of the chemicals investigated. Dietary and dermal exposure modeling indicated that exposure to reptiles was relatively high, particularly when the dermal route was considered. We conclude that caution is warranted in the use of avian receptors as surrogates for reptiles in ecological risk assessment and emphasize the need to better understand the magnitude and mechanism of contaminant exposure in reptiles to improve exposure and risk estimation. - Avian receptors are not universally appropriate surrogates for reptiles in ecological risk assessment.

Ecological models in support of regulatory risk assessments of pesticides: developing a strategy for the future.

Science.gov (United States)

Forbes, Valery E; Hommen, Udo; Thorbek, Pernille; Heimbach, Fred; Van den Brink, Paul J; Wogram, Jörn; Thulke, Hans-Hermann; Grimm, Volker

2009-01-01

This brief communication reports on the main findings of the LEMTOX workshop, held from 9 to 12 September 2007, at the Helmholtz Centre for Environmental Research (UFZ) in Leipzig, Germany. The workshop brought together a diverse group of stakeholders from academia, regulatory authorities, contract research organizations, and industry, representing Europe, the United States, and Asia, to discuss the role of ecological modeling in risk assessments of pesticides, particularly under the European regulatory framework. The following questions were addressed: What are the potential benefits of using ecological models in pesticide registration and risk assessment? What obstacles prevent ecological modeling from being used routinely in regulatory submissions? What actions are needed to overcome the identified obstacles? What recommendations should be made to ensure good modeling practice in this context? The workshop focused exclusively on population models, and discussion was focused on those categories of population models that link effects on individuals (e.g., survival, growth, reproduction, behavior) to effects on population dynamics. The workshop participants concluded that the overall benefits of ecological modeling are that it could bring more ecology into ecological risk assessment, and it could provide an excellent tool for exploring the importance of, and interactions among, ecological complexities. However, there are a number of challenges that need to be overcome before such models will receive wide acceptance for pesticide risk assessment, despite having been used extensively in other contexts (e.g., conservation biology). The need for guidance on Good Modeling Practice (on model development, analysis, interpretation, evaluation, documentation, and communication), as well as the need for case studies that can be used to explore the added value of ecological models for risk assessment, were identified as top priorities. Assessing recovery potential of exposed

A weight-of-evidence approach to assessing the ecological impact of organotin pollution in Dutch marine and brackish waters; combining risk prognosis and field monitoring using common periwinkles (Littorina littorea).

Science.gov (United States)

Schipper, Cor A; Smit, Mathijs G D; Kaag, Nicholas H B M; Dick Vethaak, A

2008-08-01

In the present study an integrated ecological risk assessment based on multiple lines of evidence (LOEs) was evaluated in order to better assess the risk from TBT in Dutch harbours and open coastal waters. On the basis of spatial distributions of measured tributyltin (TBT) concentrations in sediments and suspended matter, predictions of the intersex index (ISI) in Littorina littorea and the ecological risk expressed as the Potentially Affected Fraction (PAF) of species were made. The results were compared to actual ISI measurements and presence of L. littorea in the field. The PAF calculated on the basis of TBT levels for open coastal waters ranged from 4.2% to 15.3%; for harbours it ranged from 3.5% to 26.9%. Significant intersex levels were observed only in waters where the risk was calculated above 10% PAF. This study suggests that the absence of L. littorea from some harbours with high ecological risk values can be explained by high TBT concentrations. A call is made for the use of integrated approaches like weight-of-evidence (WOE) to help practitioners improve ecological risk assessment.

Ecological Risk Assessment of the Southern Fujian Golden Triangle in China Based on Regional Transportation Development

Directory of Open Access Journals (Sweden)

Xinyi Yang

2018-06-01

Full Text Available Regional transportation development (RTD is an important stressor of urban agglomeration ecosystems. Groundwater recharge potential may be adversely affected when natural soil is replaced by impervious materials. To systematically identify the urban agglomeration ecological risk (UAER of RTD in the southern Fujian Golden Triangle, water regulation was used as an assessment endpoint, and RTD was considered the stressor. We used the Soil Conservation Service Curve Number method (SCS-CN to analyze the internal relationship between the assessment endpoint and the stressor factors. Then, a multi-level risk characterization method was used to show the evolutionary process of risk, and to provide a scientific basis for the management of UAER. Based on the current RTD plan, the UAER assessment shows that there is a 0.90 probability of that the risk distribution results will occur by 2030. The intensity of stress from arterial roads on the urban agglomeration ecosystem is greater than that of the railway system. By considering the development of the railway system as a factor in the stress of RTD, this study of UAER assessment differs from past studies of urban ecological risk assessment, since the latter considers only highways. We also propose a systematic method of risk assessment simulation-prediction.

The Cost-Effectiveness of High-Risk Lung Cancer Screening and Drivers of Program Efficiency.

Science.gov (United States)

Cressman, Sonya; Peacock, Stuart J; Tammemägi, Martin C; Evans, William K; Leighl, Natasha B; Goffin, John R; Tremblay, Alain; Liu, Geoffrey; Manos, Daria; MacEachern, Paul; Bhatia, Rick; Puksa, Serge; Nicholas, Garth; McWilliams, Annette; Mayo, John R; Yee, John; English, John C; Pataky, Reka; McPherson, Emily; Atkar-Khattra, Sukhinder; Johnston, Michael R; Schmidt, Heidi; Shepherd, Frances A; Soghrati, Kam; Amjadi, Kayvan; Burrowes, Paul; Couture, Christian; Sekhon, Harmanjatinder S; Yasufuku, Kazuhiro; Goss, Glenwood; Ionescu, Diana N; Hwang, David M; Martel, Simon; Sin, Don D; Tan, Wan C; Urbanski, Stefan; Xu, Zhaolin; Tsao, Ming-Sound; Lam, Stephen

2017-08-01

Lung cancer risk prediction models have the potential to make programs more affordable; however, the economic evidence is limited. Participants in the National Lung Cancer Screening Trial (NLST) were retrospectively identified with the risk prediction tool developed from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. The high-risk subgroup was assessed for lung cancer incidence and demographic characteristics compared with those in the low-risk subgroup and the Pan-Canadian Early Detection of Lung Cancer Study (PanCan), which is an observational study that was high-risk-selected in Canada. A comparison of high-risk screening versus standard care was made with a decision-analytic model using data from the NLST with Canadian cost data from screening and treatment in the PanCan study. Probabilistic and deterministic sensitivity analyses were undertaken to assess uncertainty and identify drivers of program efficiency. Use of the risk prediction tool developed from the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial with a threshold set at 2% over 6 years would have reduced the number of individuals who needed to be screened in the NLST by 81%. High-risk screening participants in the NLST had more adverse demographic characteristics than their counterparts in the PanCan study. High-risk screening would cost $20,724 (in 2015 Canadian dollars) per quality-adjusted life-year gained and would be considered cost-effective at a willingness-to-pay threshold of $100,000 in Canadian dollars per quality-adjusted life-year gained with a probability of 0.62. Cost-effectiveness was driven primarily by non-lung cancer outcomes. Higher noncurative drug costs or current costs for immunotherapy and targeted therapies in the United States would render lung cancer screening a cost-saving intervention. Non-lung cancer outcomes drive screening efficiency in diverse, tobacco-exposed populations. Use of risk selection can reduce the budget impact, and

Speciation and ecological risk of heavy metals and metalloid in the sediments of Zhalong Wetland in China

International Nuclear Information System (INIS)

Ye, H.; Zang, S.; Xiao, H.; Zhang, L.

2015-01-01

A total of 271 sediments samples from the Zhalong Wetland were analyzed for concentration and distribution of Hg, Cd, As, Cu, Pb, Zn, Cr, and Zn; their speciation according to the modified European Community Bureau of Reference sequential extraction procedures and their ecological risk based on Lars Hakanson’s potential ecological risk assessment and risk assessment code were made. The results can be summarized as the followings: (1) Concentrations of all metals measured were above soil background values of Songnen Plain, and their spatial distributions were distinctly different. The concentrations of metals (except Pb) were high in the east, followed by the north, and were relatively low in the core zone and south. The concentration of Pb was high in the north, south, and west, compared with low concentration in the core zone and east. (2) The dominant proportion of Pb, Zn, and Cr was in the residual fraction, suggesting that they were environmental stable. The concentrations of Cu and As in the reducible fraction, the concentration of Cd in the acid soluble fraction, and the concentration of Hg in the oxidizable fraction were relatively high, indicating they had greater environmental effects. (3) The evaluation of the ecological risk showed that Cd, Hg, and As had relatively high ecological risk index, especially the ecological risk of Cd should be paid attention to. In general, the ecological risk of the heavy metals and metalloid by zone was experimental zone >buffering zone>ecological tourism zone>core zone.

An assessment of community health workers' ability to screen for cardiovascular disease risk with a simple, non-invasive risk assessment instrument in Bangladesh, Guatemala, Mexico, and South Africa: an observational study.

Science.gov (United States)

Gaziano, Thomas A; Abrahams-Gessel, Shafika; Denman, Catalina A; Montano, Carlos Mendoza; Khanam, Masuma; Puoane, Thandi; Levitt, Naomi S

2015-09-01

Cardiovascular disease contributes substantially to the non-communicable disease (NCD) burden in low-income and middle-income countries, which also often have substantial health personnel shortages. In this observational study we investigated whether community health workers could do community-based screenings to predict cardiovascular disease risk as effectively as could physicians or nurses, with a simple, non-invasive risk prediction indicator in low-income and middle-income countries. This observation study was done in Bangladesh, Guatemala, Mexico, and South Africa. Each site recruited at least ten to 15 community health workers based on usual site-specific norms for required levels of education and language competency. Community health workers had to reside in the community where the screenings were done and had to be fluent in that community's predominant language. These workers were trained to calculate an absolute cardiovascular disease risk score with a previously validated simple, non-invasive screening indicator. Community health workers who successfully finished the training screened community residents aged 35-74 years without a previous diagnosis of hypertension, diabetes, or heart disease. Health professionals independently generated a second risk score with the same instrument and the two sets of scores were compared for agreement. The primary endpoint of this study was the level of direct agreement between risk scores assigned by the community health workers and the health professionals. Of 68 community health worker trainees recruited between June 4, 2012, and Feb 8, 2013, 42 were deemed qualified to do fieldwork (15 in Bangladesh, eight in Guatemala, nine in Mexico, and ten in South Africa). Across all sites, 4383 community members were approached for participation and 4049 completed screening. The mean level of agreement between the two sets of risk scores was 96·8% (weighted κ=0·948, 95% CI 0·936-0·961) and community health workers showed

Identifying Relationships between High-Risk Sexual Behaviors and Screening Positive for Chlamydia and Gonorrhea in School-Wide Screening Events

Science.gov (United States)

Salerno, Jennifer; Darling-Fisher, Cindy; Hawkins, Nicole M.; Fraker, Elizabeth

2013-01-01

Background: This article describes a school-wide sexually transmitted infection (STI) screening to identify adolescent high-risk sexual behaviors, STI history/incidence, and presence of chlamydia and gonorrhea, and examines relationships between high-risk behaviors and screening positive for chlamydia and gonorrhea in an alternative high school…

Screening for Malnutrition in Community Dwelling Older Japanese: Preliminary Development and Evaluation of the Japanese Nutritional Risk Screening Tool (NRST).

Science.gov (United States)

Htun, N C; Ishikawa-Takata, K; Kuroda, A; Tanaka, T; Kikutani, T; Obuchi, S P; Hirano, H; Iijima, K

2016-02-01

Early and effective screening for age-related malnutrition is an essential part of providing optimal nutritional care to older populations. This study was performed to evaluate the adaptation of the original SCREEN II questionnaire (Seniors in the Community: Risk Evaluation for Eating and Nutrition, version II) for use in Japan by examining its measurement properties and ability to predict nutritional risk and sarcopenia in community-dwelling older Japanese people. The ultimate objective of this preliminary validation study is to develop a license granted full Japanese version of the SCREEN II. The measurement properties and predictive validity of the NRST were examined in this cross-sectional study of 1921 community-dwelling older Japanese people. Assessments included medical history, and anthropometric and serum albumin measurements. Questions on dietary habits that corresponded to the original SCREEN II were applied to Nutritional Risk Screening Tool (NRST) scoring system. Nutritional risk was assessed by the Geriatric Nutrition Risk Index (GNRI) and the short form of the Mini-Nutritional Assessment (MNA-SF). Sarcopenia was diagnosed according to the criteria of the European Working Group on Sarcopenia in Older People. The nutritional risk prevalences determined by the GNRI and MNA-SF were 5.6% and 34.7%, respectively. The prevalence of sarcopenia was 13.3%. Mean NRST scores were significantly lower in the nutritionally at-risk than in the well-nourished groups. Concurrent validity analysis showed significant correlations between NRST scores and both nutritional risk parameters (GNRI or MNA-SF) and sarcopenia. The areas under the receiver operating characteristic curves (AUC) of NRST for the prediction of nutritional risk were 0.635 and 0.584 as assessed by GNRI and MNA-SF, respectively. AUCs for the prediction of sarcopenia were 0.602 (NRST), 0.655 (age-integrated NRST), and 0.676 (age and BMI-integrated NRST). These results indicate that the NRST is a

SPECIAL SECTION: Perspectives of the Scientific Community on the Status of Ecological Risk Assessment

Science.gov (United States)

Power; Adams

1997-11-01

/ Views from a wide variety of practicing environmental professionals on the current status of ecological risk assessment (ERA) indicate consensus and divergence of opinion on the utility and practice of risk assessment. Central to the debate were the issues of whether ERA appropriately incorporates ecological and scientific principle into its conceptual paradigm. Advocates argue that ERA effectively does both, noting that much of the fault detractors find with the process has more to do with its practice than its purpose. Critics argue that failure to validate ERA predictions and the tendency to over-simplify ecological principles compromise the integrity of ERA and may lead to misleading advice on the appropriate responses to environmental problems. All authors felt that many improvements could be made, including validation, better definition of the ecological questions and boundaries of ERA, improved harmonization of selected methods, and improvements in the knowledge base. Despite identified deficiencies, most authors felt that ERA was a useful process undergoing evolutionary changes that will inevitably determine the range of environmental problems to which it can be appropriately applied. The views expressed give ERA a cautious vote of approval and highlight many of the critical strengths and weaknesses in one of our most important environmental assessment tools.KEY WORDS: Ecological risk assessment; Ecology; Probability

Randomized controlled trial of storytelling compared to a personal risk tool intervention on colorectal cancer screening in low-income patients.

Science.gov (United States)

Larkey, Linda K; McClain, Darya; Roe, Denise J; Hector, Richard D; Lopez, Ana Maria; Sillanpaa, Brian; Gonzalez, Julie

2015-01-01

Screening rates for colorectal cancer (CRC) lag for low-income, minority populations, contributing to poorer survival rates. A model of storytelling as culture-centric health promotion was tested for promoting CRC screening. A two-group parallel randomized controlled trial. Primary care, safety-net clinics. Low-income patients due for CRC screening, ages 50 to 75 years, speaking English or Spanish. Patients were exposed to either a video created from personal stories composited into a drama about "Papa" receiving CRC screening, or an instrument estimating level of personal cancer risk. Patients received a health care provider referral for CRC screening and were followed up for 3 months to document adherence. Behavioral factors related to the narrative model (identification and engagement) and theory of planned behavior. Main effects of the interventions on screening were tested, controlling for attrition factors, and demographic factor associations were assessed. Path analysis with model variables was used to test the direct effects and multiple mediator models. Main effects on CRC screening (roughly half stool-based tests, half colonoscopy) did not indicate significant differences (37% and 42% screened for storytelling and risk-based messages, respectively; n = 539; 33.6% male; 62% Hispanic). Factors positively associated with CRC screening included being female, Hispanic, married or living with a partner, speaking Spanish, having a primary care provider, lower income, and no health insurance. Engagement, working through positive attitudes toward the behavior, predicted CRC screening. A storytelling and a personalized risk-tool intervention achieved similar levels of screening among unscreened/underscreened, low-income patients. Factors usually associated with lower rates of screening (e.g., no insurance, being Hispanic) were related to more adherence. Both interventions' engagement factor facilitated positive attitudes about CRC screening associated with behavior

Approach and strategy for performing ecological risk assessments for the U.S. Department of Energy's Oak Ridge Reservation: 1994 revision

International Nuclear Information System (INIS)

Suter, G.W. II; Sample, B.E.; Jones, D.S.; Ashwood, T.L.

1994-08-01

This report provides guidance for planning and performing ecological risk assessments on the Oak Ridge Reservation (ORR). The tiered approach to ecological risk assessment has been implemented, generic conceptual models have been developed, and a general approach for developing ecological assessment endpoints and measurement endpoints has been agreed upon. The document also includes changes in terminology to agree with the terminology in the US Environmental Protection Agency's (EPA's) framework for ecological risk assessment. Although ecological risks are equal in regulatory importance to human health risks, formal procedures for ecological risk assessment are poorly developed. This report will provide specific guidance and promote the use of consistent approaches for ecological risk assessments at individual sites on the ORR. The strategy discussed in this report is consistent with the overall strategy for site management and Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) compliance and with relevant EPA guidance. The general approach and strategy presented herein was developed for the ORR, but it should be applicable to other complex CERCLA sites that possess significant ecological resources

[Uncertainty characterization approaches for ecological risk assessment of polycyclic aromatic hydrocarbon in Taihu Lake].

Science.gov (United States)

Guo, Guang-Hui; Wu, Feng-Chang; He, Hong-Ping; Feng, Cheng-Lian; Zhang, Rui-Qing; Li, Hui-Xian

2012-04-01

Probabilistic approaches, such as Monte Carlo Sampling (MCS) and Latin Hypercube Sampling (LHS), and non-probabilistic approaches, such as interval analysis, fuzzy set theory and variance propagation, were used to characterize uncertainties associated with risk assessment of sigma PAH8 in surface water of Taihu Lake. The results from MCS and LHS were represented by probability distributions of hazard quotients of sigma PAH8 in surface waters of Taihu Lake. The probabilistic distribution of hazard quotient were obtained from the results of MCS and LHS based on probabilistic theory, which indicated that the confidence intervals of hazard quotient at 90% confidence level were in the range of 0.000 18-0.89 and 0.000 17-0.92, with the mean of 0.37 and 0.35, respectively. In addition, the probabilities that the hazard quotients from MCS and LHS exceed the threshold of 1 were 9.71% and 9.68%, respectively. The sensitivity analysis suggested the toxicity data contributed the most to the resulting distribution of quotients. The hazard quotient of sigma PAH8 to aquatic organisms ranged from 0.000 17 to 0.99 using interval analysis. The confidence interval was (0.001 5, 0.016 3) at the 90% confidence level calculated using fuzzy set theory, and the confidence interval was (0.000 16, 0.88) at the 90% confidence level based on the variance propagation. These results indicated that the ecological risk of sigma PAH8 to aquatic organisms were low. Each method has its own set of advantages and limitations, which was based on different theory; therefore, the appropriate method should be selected on a case-by-case to quantify the effects of uncertainties on the ecological risk assessment. Approach based on the probabilistic theory was selected as the most appropriate method to assess the risk of sigma PAH8 in surface water of Taihu Lake, which provided an important scientific foundation of risk management and control for organic pollutants in water.

Benchmarks for Developing Ecological Soil Screening Levels (ECO-SSL): Effects of Selenium on Soil Invertebrates

National Research Council Canada - National Science Library

Checkai, Ronald T; Simini, Michael; Kuperman, Roman; Phillips, Carlton T; Johnson, Dennis W; Higashi, Richard M; Fan, Teresa W-M; Sappington, Keith

2004-01-01

...) for ecological receptors. Unfortunately data in the published literature were insufficient in quantity and quality to establish an Eco-SSL for selenium, critical in various DoD advanced technologies, and frequently...

Probabilistic and deterministic risk assessment for extreme objects and ecologically hazardous systems

Directory of Open Access Journals (Sweden)

Yu. V. Veryuzhsky

2003-06-01

Full Text Available The paper include mostly the results of works of the Research Institute for Mechanics of Quickproceeding Processes united in a general research direction - creation of the methodology for risk assessment and risk management for ecologically hazardous systems, consisting of the set of different technological analyzed objects. The elements of system can be characterized by high level of radiation, toxic, explosion, fire and other hazards. The probalistic and deterministic approach for risk assessment, based on mathematical methods of system analysis, non-liner dynamics and computer simulation, has been developed. Branching in problem definition, as well as diversity of factor and criteria for determination of system status, is also taken into account. The risks caused by both objective and subjective factors (including human factor are examined. In many performed studies, the leading structural element, dominating in determination of the system safety, is the structural part of an object. The methodology is implemented for the safety analysis (risk assessment for Chernobyl NPP Shelton Object and other industrial buildings

Calcium toxicity in a freshwater stream: Results of an ecological risk assessment

International Nuclear Information System (INIS)

Jones, D.S.; Stewart, A.J.; Smith, J.G.; Phipps, T.L.

1995-01-01

Calcium and other essential elements are often excluded a priori from ecological risk assessments. However, calcium can be a credible contaminant of ecological concern in systems with high concentrations of anions. A baseline ecological risk assessment was performed as part of the CERCLA Remedial Investigation of Bear Creek Valley at the Y-12 Plant in Oak Ridge, TN. Unlined surface impoundments at the headwaters of Bear Creek (BC) received nitric acid waste solutions between 1951 and 1984. The resulting groundwater plume now discharges into BC and contains high concentrations of nitrates and dissolved metals, including calcium. Weight-of-evidence suggests that BC water poses a significant risk to benthic invertebrates. The three available lines of evidence indicate that calcium contributes to these risks: (1) dissolved calcium concentrations in upper BC exceed the chronic value for Daphnia magna and a previous evaluation of the charge balance suggested that the solubility of calcium in BC is high because of high concentrations of nitrate ions; (2) water from BC inhibits Ceriodaphnia dubia reproduction and calcium concentrations explained approximately 80% of the variation in this inhibition; (3) the benthic invertebrate community in upper BC, and in particular the Ephemeroptera, are severely degraded, relative to reference streams. These findings serve as a reminder that contaminants of potential ecological concern need to be evaluated on a case-by-case basis and that interactions among contaminants may yield unexpected results

MRI screening for breast cancer in women at high risk; is the Australian breast MRI screening access program addressing the needs of women at high risk of breast cancer?

Energy Technology Data Exchange (ETDEWEB)

Schenberg, Tess [Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria (Australia); Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria (Australia); Mitchell, Gillian [Familial Cancer Centre, Peter MacCallum Cancer Centre, Melbourne, Victoria (Australia); Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria (Australia); Taylor, Donna [School of Surgery, University of Western Australia, Perth, Western Australia (Australia); Department of Radiology, Royal Perth Hospital, Perth, Western Australia (Australia); BreastScreen Western Australia, Adelaide Terrace, Perth, Western Australia (Australia); Saunders, Christobel [School of Surgery, University of Western Australia, Perth, Western Australia (Australia); Department of General Surgery, St John of God Hospital, Perth, Western Australia (Australia); Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria (Australia)

2015-09-15

Breast magnetic resonance imaging (MRI) screening of women under 50 years old at high familial risk of breast cancer was given interim funding by Medicare in 2009 on the basis that a review would be undertaken. An updated literature review has been undertaken by the Medical Services Advisory Committee but there has been no assessment of the quality of the screening or other screening outcomes. This review examines the evidence basis of breast MRI screening and how this fits within an Australian context with the purpose of informing future modifications to the provision of Medicare-funded breast MRI screening in Australia. Issues discussed will include selection of high-risk women, the options for MRI screening frequency and measuring the outcomes of screening.

MRI screening for breast cancer in women at high risk; is the Australian breast MRI screening access program addressing the needs of women at high risk of breast cancer?

International Nuclear Information System (INIS)

Schenberg, Tess; Mitchell, Gillian; Taylor, Donna; Saunders, Christobel

2015-01-01

Breast magnetic resonance imaging (MRI) screening of women under 50 years old at high familial risk of breast cancer was given interim funding by Medicare in 2009 on the basis that a review would be undertaken. An updated literature review has been undertaken by the Medical Services Advisory Committee but there has been no assessment of the quality of the screening or other screening outcomes. This review examines the evidence basis of breast MRI screening and how this fits within an Australian context with the purpose of informing future modifications to the provision of Medicare-funded breast MRI screening in Australia. Issues discussed will include selection of high-risk women, the options for MRI screening frequency and measuring the outcomes of screening

Cytogenetic screening of population living in ecologically unfavourable region of Semipalatinsk region

International Nuclear Information System (INIS)

Kundakbaeva, G.B.

1998-01-01

Cytogenetic examination of groups of people from ecologically unfavourable region of 4 settlements located at different distance from the center of nuclear explosions was conducted. For purpose of conducting biological indication and dosimetry, the radio sensibility of cells peripheral blood was determined with the account for the sex and age of the individuals from examined groups of people. Correlation analysis of frequency of chromosome aberration (CA) was implement taking into account the sex, age and absorbed dose of radiation. It was established that the frequency of chromosome aberration in examined groups exceed the control level 3,5 times (1,63±0,26). It was shown that total frequency of CA from people constituted: the Dolon settlement (zone of extreme risk) - 6,16±1,23 per 100 analyzed metaphases; the Kononerka settlement (zone of maximum risk) - 4,4 ±0,84; the Ramadan settlement (zone of maximum risk) - 5,97±1,08. Frequency of radiation induction chromosome markets within the region constituted 0,41±0,16 per 100 cells as average, - this exceeds control level (0,67±0,002) 6 times. Considerable factions (0,5-17,7 %) of exit of chromosome aberrations were discovered among different individuals. It was established that the frequency of stable and unstable CA increases due to the age of the people examined. Using the method of biological dosimetry based of registration of frequency of stable and unstable CA it was established that the population of examined regions has probably absorbed the following doses: the Dolon settlement - 0,14 Gy, the Kanonerka settlement - 0,13 Gy, the Buras settlement - 0,06 Gy, the Ramadan - 0,095 Gy. (author)

Methodology for the Model-based Small Area Estimates of Cancer Risk Factors and Screening Behaviors - Small Area Estimates

Science.gov (United States)

This model-based approach uses data from both the Behavioral Risk Factor Surveillance System (BRFSS) and the National Health Interview Survey (NHIS) to produce estimates of the prevalence rates of cancer risk factors and screening behaviors at the state, health service area, and county levels.