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Sample records for scotia depot scotia

  1. School Psychology in Nova Scotia

    Science.gov (United States)

    King, Sara; McGonnell, Melissa; Noyes, Amira

    2016-01-01

    Registration as a psychologist in Nova Scotia can be at the master's or doctoral level; however, the Nova Scotia Board of Examiners in Psychology has announced a move to the doctoral degree as the entry-level to practice. Many school psychologists in Nova Scotia practice at the master's level; therefore, this change could affect school psychology…

  2. Franchising in Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Hoffman, G. [Nova Scotia Petroleum Directorate, Halifax, NS (Canada)

    1998-09-01

    Opportunities for the local distribution of natural gas in Nova Scotia were reviewed, with special emphasis on franchising. Franchising in Nova Scotia began in 1980, made possible by the passage of the Gas Utilities Act and the Pipeline Act which promised western Canadian natural gas to eastern Canada. However, proposals for franchisees to distribute natural gas in the province were abandoned as the hope for natural gas transmission service to the province faded. The plummeting of world oil prices by the mid-1980s was also a contributory factor. Discovery and development of natural gas facilities around Sable Island led to the September 1997 proclamation of the Gas Distribution Act, which also led to the revival of interest in franchising. The Act provides for the competitive marketing of natural gas as a commodity and the regulation of the gas delivery system under a franchise agreement. Competitive applications are expected early in 1998, with awards of franchises in late 1998. Construction and gas delivery services should begin operations late in 1999.

  3. Franchising in Nova Scotia

    International Nuclear Information System (INIS)

    Hoffman, G.

    1998-01-01

    Opportunities for the local distribution of natural gas in Nova Scotia were reviewed, with special emphasis on franchising. Franchising in Nova Scotia began in 1980, made possible by the passage of the Gas Utilities Act and the Pipeline Act which promised western Canadian natural gas to eastern Canada. However, proposals for franchisees to distribute natural gas in the province were abandoned as the hope for natural gas transmission service to the province faded. The plummeting of world oil prices by the mid-1980s was also a contributory factor. Discovery and development of natural gas facilities around Sable Island led to the September 1997 proclamation of the Gas Distribution Act, which also led to the revival of interest in franchising. The Act provides for the competitive marketing of natural gas as a commodity and the regulation of the gas delivery system under a franchise agreement. Competitive applications are expected early in 1998, with awards of franchises in late 1998. Construction and gas delivery services should begin operations late in 1999

  4. Nova Scotia electricity update

    International Nuclear Information System (INIS)

    Crandlemire, A.L.

    2004-01-01

    This paper provides an update of electricity issues concerning Nova Scotia such as supply, capacity, emission commitments, as well as co-generation and the Electricity Marketplace Governance Committee (EMGC). The goals of the strategy were reliability combined with competitive prices and greater environmental responsibility. The scope of these objectives included new capacity, transmission, renewables and co-generation. Other objectives included encouraging wholesale market competition; meeting reciprocity requirements; and a 50 MW renewable energy target. Recommendations of the EMGC included wholesale market competition; a broader market scope with a cost benefit analysis; Open Access Transmission Tariff (OATT); a scheduling and information system; network integration and a point to point service; and a separation of transmission and generation business units. Other recommendations included an open competitive process for new generation; a consideration of emissions and overall efficiency; a Renewable Energy Portfolio Standard (RPS) to start in 2006; the separation of RPS tags from electricity; and net metering of renewables. These recommendations were accepted in 2003, followed by the new Electricity Act in 2004, which made OATT mandatory, established RPS and opened to the wholesale market. Capacity at present was considered to be tight, with preparations for the new regulations under way. Reductions in air pollution were reported at 25 per cent, with renewable energy projects such as 2 windmills currently under way, as well as various other projects. Opportunities for provincial Atlantic cooperation were identified as being management of reserve requirements; trading of lowest cost electricity; new generation on a regional scale; stronger transmission ties; a system operator; a regional approach to RPS; regional management of air emissions; and regional opportunities for Carbon dioxide reductions. tabs., figs

  5. Gas distribution regulations (Nova Scotia)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-03

    A consolidation of Nova Scotia`s gas distribution regulations made under subsection 42(1) of the Gas Distribution Act S.N.S. 1997, c4 - O.I.C. 1998-576 (November 10, 1998), N.S. Reg. 86/98 are presented. The consolidation is issued for reference purposes only, and while it has no official sanction, it is considered useful in providing an interpretation of the regulation, explaining franchise evaluation, the granting of franchises, and exemptions from application requirements. 1 tab.

  6. Climate change in Nova Scotia : a background paper to guide Nova Scotia's climate change action plan

    International Nuclear Information System (INIS)

    2007-10-01

    Climate change causes changes in the temperature of the earth, the level of the sea, and the frequency of extreme weather conditions. The province of Nova Scotia recently released an act related to environmental goals and sustainable prosperity. Addressing climate change is a key element in achieving Nova Scotia's sustainable prosperity goals outlined in the act. The Nova Scotia Department of Energy is working towards developing both policy and action, to help meet its target of a 10 per cent reduction in greenhouse gases from 1990 levels by the year 2020. Two major plans are underway, notably a climate change action plan and a renewed energy strategy. This report provided background information on Nova Scotia's climate change action plan. It discussed climate change issues affecting Nova Scotia, air pollutants, energy sources in Nova Scotia, energy consumers in the province, and Nova Scotia's approach to climate change. The report also discussed actions underway and funding sources. It was concluded that in order for the climate change action plan to be successful, Nova Scotians must use energy more efficiently; use renewable energy; use cleaner energy; and plan for change. 13 refs., 2 tabs., 6 figs., 4 appendices

  7. Uranium in Nova Scotia: a background summary for the uranium inquiry, Nova Scotia

    International Nuclear Information System (INIS)

    1982-01-01

    Since the mid 1970's Nova Scotia has experienced increased exploration for a number of commodities including uranium. The exploration activity for uranium has resulted in discovery of significant occurrences of the element. It became obvious to the Government of Nova Scotia that a segment of the population of the Province is concerned about the potential hazards associated with the exploration, mining and milling stages of the uranium industry. Public concern has resulted in the appointment of a Commissioner under the Public Inquiries Act of Nova Scotia to inquire and make recommendations to the Governor-in-Council on all aspects of exploration, development, mining, processing, storage, waste management and transportation of uranium in any form. The regulation of mineral exploration and mining activities is carried out by the Nova Scotia Department of Mines and Energy through the Mineral Resources Act of the Province of Nova Scotia. The regulation of the special radioactive aspects involved in the mining and processing of uranium ore is the responsibility of the federal Atomic Energy Control Board. The purposes of this report is to: outline the history of uranium exploration in Nova Scotia; summarize the results of geological surveys by provincial and federal government agencies, universities and exploration companies which document the natural levels of radioactivity in the Province; briefly outline the physical and chemical characteristics of uranium and thorium which make these elements unique and a potential environmental and health concern; outline chronologically the steps taken by the Nova Scotia Department of Mines and Energy to monitor and regulate uranium exploration activities; classify the types of uranium deposits known to occur in Nova Scotia and describe their main geological features; outline the role of the Nova Scotia Department of Mines and Energy in the regulation of mining activities in the Province. The report is written for the interested

  8. Nova Scotia Power : in-stream tidal

    International Nuclear Information System (INIS)

    Meade, K.

    2007-01-01

    The Government of Nova Scotia, the Government of New Brunswick, Nova Scotia Power and others have funded a feasibility study of North American sites for commercial instream tidal power. In July 2007, Nova Scotia Power received partial funding for a demonstration project. This presentation provided information on a demonstration plant for tidal power run by Nova Scotia Power. It discussed the benefits of the Open Hydro technology for this plant. In this simple design, the generator is on the circumference of the turbine. The design does not involve any power transmission systems or any pitching of blades. In addition, the technology is environmentally sound as it is completely shrouded, has low rotational speed, and a large open centre allows fish to pass through, and it does not require lubricants. The last benefit that was presented was the scale up of 250 kW machine deployed in a European test facility. The presentation also discussed the advantages of developing tidal power at this time. It was concluded that tidal energy has significant potential. Although it is intermittent, it is predictable and bulk power system can be scheduled to accommodate it. figs

  9. Coalfields west half Cumberland County, Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Copeland, M J

    1958-01-01

    A geologic survey of the coal fields of the western half of Cumberland County, Nova Scotia was performed including studies of the structural geology, stratigraphy, and paleontology of the area. One part of this survey included a spectrographic analysis of 55 coals for 23 elements. These analyses are presented in tabular form.

  10. Nova Scotia wind integration study : final report

    International Nuclear Information System (INIS)

    2008-01-01

    An independent study was commissioned by the Nova Scotia Department of Energy to identify and assess the impacts of integrating large scale wind power generation into Nova Scotia's electric power system. The purpose of the study was to help Nova Scotia's efforts towards building its renewable energy supply, in order to secure a local energy resource and to protect the environment. This report provided an overview of Nova Scotia's electric power sector, including organizations involved; existing generation system; existing transmission system; renewable energy standards; Nova Scotia Power integrated resource plan; and 2007 renewable energy request for proposals. The major assumptions for the study that were discussed included system parameters; system capacity reserve requirements; expansion plans to 2020; and allocation of new wind generation by zone. Wind resource data and system dispatch modeling were also presented and transmission system modeling was outlined. This included a discussion of steady state reliability requirements; inputs to the load flow model; load flow study and contingency analysis; intra-province transmission congestion; and potential impacts on system security. The report also presented an approach to impact analysis and mitigation such as the impact on greenhouse gas and other air emissions and the impact of wind energy prices on system costs. It was concluded that one of the most important factors in evaluation of the economic impact of wind power integration is the forecasted fuel prices for the thermal units. If the fuel prices had varied significantly from the forecasted values, the study economic impact results could have been quite different. 55 tabs., 64 figs., 1 appendix

  11. Nova Scotia Resources Limited annual report, 1992

    International Nuclear Information System (INIS)

    1992-01-01

    Nova Scotia Resources was established in 1981 by the provincial government to invest in and manage Nova Scotia's participation in petroleum, energy, and mineral development. The company and its subsidiaries hold interests in oil and gas discovery areas and producing fields in the Nova Scotia offshore, and owns producing oil and gas interests in western Canada. In June 1992, oil production began from the Cohasset project, representing Canada's first commercial offshore oil production. Nearly 4 million bbl of crude will be sold in the first production season. Work is continuing on additional producing wells; the production life of the Cohasset project is currently estimated at 6 y. Offshore exploration activity is also continuing under four exploration licenses. For the 12 months ending March 31, 1992, net earnings from western oil and gas production were $369,000. Total gross revenues from oil and gas producing properties for the year were ca $4.8 million. Other 1992 activities include active exploration for salt and potash sites with potential for underground storage of natural gas. Financial statements are included. 14 figs., 2 tabs

  12. Nova Scotia Energy Strategy : progress report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-02-01

    Nova Scotia's energy strategy addresses all aspects of energy production and use, from offshore oil and gas to electricity and coal, to climate change and renewable resources. It also encompasses energy conservation and efficiency. This progress report highlights the efforts that the province has made to promote exploration, improve efficiency of regulations and approval processes and promote the oil and natural gas sector. Efforts have also been made to support local businesses, address climate change issues and protect the environment. The strategy demonstrates how new energy resources can be used to build a more prosperous and self-reliant province. The progress report focuses on the following 3 themes: powering the economy; improving the environment; and, securing Nova Scotia's future. The report emphasizes that the growing oil and gas industry brings many opportunities for new jobs and a stronger economy. In the next 12 to 18 months, about 8 to 10 offshore exploration wells will be drilled, which is more than in the last decade. Funding will be provided to extend pipeline systems beyond franchise areas approved by the Nova Scotia Utility and Review Board. In May 2002, the Electricity Marketplace Governance Committee was formed to make recommendations on how competition can be introduced into the province's electricity market. The Department of Energy has been working to implement initiatives to increase the use of renewable energy sources such as solar and wind power. In October 2002, new wind turbines began producing electricity in 3 communities on Cape Breton Island. A key priority is to respond to climate change and reduce greenhouse gas emissions as well as emissions of mercury, sulphur, nitrogen, and ozone. The energy strategy also identifies the need to provide competitive taxation regimes.

  13. Legislating Interprofessional Regulatory Collaboration in Nova Scotia

    Directory of Open Access Journals (Sweden)

    William Lahey

    2013-10-01

    Full Text Available To shift health professions regulation from traditional to ‘collaborative’ self-regulation, Nova Scotia has adopted legislation which will: make all self-regulating health professions members of the Regulated Health Professions Network; mandate the Network to facilitate voluntary collaboration among its members; and enable regulators to work together on investigations of patient complaints, to adjust scopes of practice on an ongoing basis and to adjudicate appeals of unsuccessful applicants for registration. The goals are to give health professions regulation the capacity to enable and support the functioning of interprofessional teams. The legislation was adopted primarily for two reasons: collaborative development and unanimous support by all of the province’s self-regulating professions; and alignment with the government’s health care reform agenda and its emphasis on collaborative team-based care. Contrary to the approach of several other provinces, the legislation will enable but not require regulators to collaborate on the premise that consensual collaboration is more likely to happen, to be meaningful and to yield tangible benefits. Support for this approach can be taken from the impressive collaborative work on which the legislation is based. Evaluation will be critical, and the five-year review required by the legislation will give Nova Scotia the opportunity to test not only the legislation but the ideas on which it is based. The extent of the legislation’s reliance on voluntary process will prove to be either its greatest strength or its greatest weakness.

  14. Ocean and Coastal Acidification off New England and Nova Scotia

    Science.gov (United States)

    New England coastal and adjacent Nova Scotia shelf waters have a reduced buffering capacity because of significant freshwater input, making the region’s waters potentially more vulnerable to coastal acidification. Nutrient loading and heavy precipitation events further acid...

  15. Big and Little Feet Provincial Profiles: Nova Scotia

    Directory of Open Access Journals (Sweden)

    Sarah Dobson

    2017-09-01

    Full Text Available This communiqué provides a summary of the production- and consumption-based greenhouse gas emissions accounts for Nova Scotia, as well as their associated trade flows. It is part of a series of communiqués profiling the Canadian provinces and territories.1 In simplest terms, a production-based emissions account measures the quantity of greenhouse gas emissions produced in Nova Scotia. In contrast, a consumption-based emissions account measures the quantity of greenhouse gas emissions generated during the production process for final goods and services that are consumed in Nova Scotia through household purchases, investment by firms and government spending. Trade flows refer to the movement of emissions that are produced in Nova Scotia but which support consumption in a different province, territory or country (and vice versa. For example, emissions at the Port of Halifax that are associated with goods that are subsequently exported to Ontario for sale are recorded as a trade flow from Nova Scotia to Ontario. Moving in the opposite direction, emissions associated with the production of motor gasoline in New Brunswick that is exported to Nova Scotia for sale are recorded as a trade flow from New Brunswick to Nova Scotia. For further details on these results in a national context, the methodology for generating them and their policy implications, please see the companion papers to this communiqué series: (1 Fellows and Dobson (2017; and (2 Dobson and Fellows (2017. Additionally, the consumption emissions and trade flow data for each of the provinces and territories are available at: http://www.policyschool.ca/embodied-emissions-inputs-outputs-datatables-2004-2011/.

  16. Regulating and Funding Midwifery in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Annie Morrison

    2014-07-01

    Full Text Available Midwives have been working in Nova Scotia for many years, and midwifery became a government funded and regulated health profession in the province in 2009. Despite the will among many decision-makers in the province to regulate the profession since the mid 1980s, several elections and lack of a management model slowed the program’s development. Implicit goals of having midwifery services included improving the quality of maternal care and health outcomes, keeping up with other provinces, responding to public demand, and saving costs. Strong and persistent bureaucratic and public advocacy work, inter-party collaboration, and research demonstrating positive and safe maternal and newborn health outcomes under midwifery care all had a role in the decision-making process. The implementation responsibility was delegated to three health districts in the province, each being responsible for designing a program to integrate midwives into maternal health care teams. The program has thus far been evaluated in an ad hoc manner with external teams performing comprehensive assessments, though the need for a cost-benefit analysis as well as more systematic assessments has been identified. Though many opportunities exist with midwifery in the province, including a continued high demand for the service, and research demonstrating positive outcomes for mothers and babies, significant challenges and threats remain to be addressed to ensure long-term sustainability of the program.

  17. The geographic accessibility of pharmacies in Nova Scotia.

    Science.gov (United States)

    Law, Michael R; Heard, Deborah; Fisher, Judith; Douillard, Jay; Muzika, Greg; Sketris, Ingrid S

    2013-01-01

    Geographic proximity is an important component of access to primary care and the pharmaceutical services of community pharmacies. Variations in access to primary care have been found between rural and urban areas in Canadian and international jurisdictions. We studied access to community pharmacies in the province of Nova Scotia. We used information on the locations of 297 community pharmacies operating in Nova Scotia in June 2011. Population estimates at the census block level and network analysis were used to study the number of Nova Scotia residents living within 800 m (walking) and 2 km and 5 km (driving) distances of a pharmacy. We then simulated the impact of pharmacy closures on geographic access in urban and rural areas. We found that 40.3% of Nova Scotia residents lived within walking distance of a pharmacy; 62.6% and 78.8% lived within 2 km and 5 km, respectively. Differences between urban and rural areas were pronounced: 99.2% of urban residents lived within 5 km of a pharmacy compared with 53.3% of rural residents. Simulated pharmacy closures had a greater impact on geographic access to community pharmacies in rural areas than urban areas. The majority of Nova Scotia residents lived within walking or short driving distance of at least 1 community pharmacy. While overall geographic access appears to be lower than in the province of Ontario, the difference appears to be largely driven by the higher proportion of rural dwellers in Nova Scotia. Further studies should examine how geographic proximity to pharmacies influences patients' access to traditional and specialized pharmacy services, as well as health outcomes and adherence to therapy. Can Pharm J 2013;146:39-46.

  18. Nova Scotia's new gas distribution regime

    Energy Technology Data Exchange (ETDEWEB)

    MacIsaac, J.B. [Cox Hanson O' Reilly Matheson, Halifax, NS (Canada)

    2002-07-01

    The most recent amendments to Nova Scotia's gas distribution regime were described in detail. The amended legislation includes: (1) elimination of mandatory service targets, (2) franchise terms of 25 years, (3) a 10 year prohibition on industrial by-pass, (4) gas sales licenses are now required to market gas in Nova Scotia, (5) distributors can offer bundled services, (6) the elimination of province wide uniform tolls for low volume customers, (7) public utilities are permitted to apply for a distribution franchise and to market natural gas, (8) ex-party filing of interim rates, (9) the Pipeline Act applies to the construction of gas distribution systems, (10) socio-economic studies are required for parties seeking a single-end user franchise outside a franchise area, and (11) regulations for underground gas storage have been removed from the legislation. It was noted that these significant changes to the statutory framework of Nova Scotia's delivery of natural gas are sending encouraging signals to parties considering investing in the distribution network in the province. It was also noted, that as in any industry, success of natural gas distribution in Nova Scotia will depend on economics and not on structural changes. 66 refs.

  19. Proceedings of Nova Scotia's 2006 energy research and development forum

    International Nuclear Information System (INIS)

    2006-01-01

    The Nova Scotia 2006 energy research and development forum provided a venue for experts from industry, research institutions and government to discuss how research and development will shape the future of energy in the province. The forum was divided into 3 sessions: (1) building knowledge about the marine environment, (2) building knowledge about geoscience, and (3) building knowledge about sustainable energy. A wide ranges of issues related to the Nova Scotia region included whale identification; fisheries mapping; the commercialization of hydrocarbon discoveries; carbon capture and storage and petroleum system analysis and prospect evaluation. Keynote addresses were presented on produced water in Norway; deepwater exploration in Morocco; renewable energy and Canada's role as an energy superpower. The conference featured more than 57 presentations, of which 4 have been catalogued separately for inclusion in this database. refs., tabs., figs

  20. Bioidentical hormone therapy: Nova Scotia pharmacists’ knowledge and beliefs

    OpenAIRE

    Whelan, Anne Marie; Thebeau, Jean-Pierre; Jurgens, Tannis M.; Hurst, Eileen

    2012-01-01

    Objectives: To investigate Nova Scotia (NS) pharmacists´ knowledge and beliefs regarding the use of bioidentical hormones (BHs) for the management of menopause related symptoms. Methods: Using Dillman´s tailored design methodology, an invitation to complete the web-based questionnaire was emailed to pharmacists in NS as part of the Dalhousie College of Pharmacy Continuing Pharmacy Education Department´s (CPE) weekly email update. Data was analyzed using descriptive statistics. Results: Of app...

  1. Policy statement on gas distribution in Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-01-30

    This paper presented Nova Scotia's policy related to gas distribution. The government of Nova Scotia views natural gas as an economic enabler and is committed to ensuring that natural gas is available and accessible to Nova Scotians where it is economically feasible. Natural gas will give the province an efficient and clean burning energy supply that will make existing businesses more competitive. The province will support and facilitate the construction and operation of a gas distribution system by the private sector and will ensure that there is regulatory oversight by the Nova Scotia Utility and Review Board to protect the public interest. The government will also develop a plan for early conversion of government buildings to natural gas. This paper described the province's policy on gas distribution in relation to: (1) a province-wide franchise, (2) a supplemental franchise, (3) cost of service/performance based rates, (4) postage stamp rates, (5) a Maritimes and Northeast lateral policy, (6) direct access/bypass, (7) existing direct access user, (8) bundling of gas sales and other products and services, (9) licensing of gas marketers, (10) benefits, (11), regulatory efficiency, (12) municipal taxes, and (13) municipal operating agreements.

  2. Industry and improvement: state and class formations in Nova Scotia`s coal-mining countryside, 1790-1864

    Energy Technology Data Exchange (ETDEWEB)

    Samson, D.J.

    1997-12-31

    The role of state and class formation in Nova Scotia before Confederation is discussed. The farming and coal mining districts of northern Nova Scotia are described as opposing segments that together were central to the development of liberal capitalist government forms in the province. A range of economic circumstances is considered: squatters, estates, mixed farming, coal mining, trading, quarrying, and fraternal societies. The role of enterprises such as the General Mining Association, a British venture, in colonization and in constraint of local initiative and accumulation is considered. Rural liberals created a positive place in self-government, while colonial liberals constructed a liberalism that was centred around the state and economic progress. The poor and those without property were allotted marginal public roles.

  3. Structure of Subsurface Sediments in the Scan Basin (Scotia Sea)

    Science.gov (United States)

    Schreider, Al. A.; Schreider, A. A.; Sazhneva, A. E.; Galindo-Zaldivar, J.; Ruano, P.; Maldonado, A.; Martos-Martin, Y.; Lobo, F.

    2018-01-01

    The structure of sediments in the Scotia Sea is used as a basis for reconstructing the geological history of its bottom in the Late Quaternary. The Scan Basin is one of the main elements of the topography of the southern Scotia Sea. Its formation played a considerable role in the fragmentation of the continent, which included the Bruce and Discovery banks. The main parameters of the sediment layer in the Scan Basin have been reconstructed by the present time, but its top part has not been studied. In this work, we analyze the first data obtained on the R/V Gesperidas with the use of a TOPAS PS 18/40 high-resolution seismic profilograph in 2012. Three layers in the subsurface sediments on the bottom of the Scan Basin were specified for the first time. The mean periods of their deposition in the Late Quaternary were determined as 115000 years for the first, 76000 years for the second, and 59 000 years for the third layer from the surface of the bottom. The duration of the total accumulation period of the three layers is about 250000 years.

  4. Marine renewable energy legislation for Nova Scotia : policy background paper

    International Nuclear Information System (INIS)

    2010-07-01

    Marine renewable energy sources can provide Nova Scotia with a large supply of sustainable, non-carbon emitting electricity. One of the largest tidal ranges within the world is contained within the Bay of Fundy, which holds power potential in the form of wind, wave and tidal energy. A strategic environmental assessment (SEA) on the Bay of Fundy's potential marine renewable energy was published in 2008. An assessment of the social, economic, and environmental effects and factors linked with possible development of renewable energy sources in the Bay Fundy was published. Twenty-nine recommendations were offered, including the creation of marine renewable energy legislation incorporating sustainability principles. This discussion paper described the policy drivers and opportunities in Nova Scotia for marine renewable energy sources as well as the challenges and relevant subject areas that should be considered when creating marine renewable energy legislation and policy. Specific challenges that were discussed included a policy approach to development; multiple jurisdictions; Aboriginal issues; economic factors; environmental impacts; occupational and operation safety; allocation of rights; and regulatory issues. It was concluded that if the marine renewable energy resource was going to be created with the possibility of providing commercial electricity generation, a coordinated legislative framework should be established. refs., tabs.

  5. Air quality guidelines for arenas in Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    A series of guidelines have been prepared to address the quality of air in skating arena facilities in Nova Scotia. They are limited to carbon monoxide and nitrogen dioxide emissions. Average nitrogen dioxide levels should not exceed 1 part per million (ppm). Average carbon monoxide levels should not exceed 25 ppm. These guidelines do not address other contaminants such as ammonia or chlorofluorocarbons (CFCs). The guidelines are considered to be the minimum standards required for safe arena operations. These standards can be met by reducing emissions of the ice resurfacer and edger which is one of the major sources of poor air quality in arenas. Other ways to meet the standards are to ensure proper equipment operation, ventilation and monitoring of indoor air quality levels. Symptoms of exposure and potential consequences were also described. It was noted that owners and operators may be found libel for injury if a proper environment is not maintained. 6 appendices.

  6. An Emerging Wine Region in Nova Scotia, Canada: Terroir Trials and Tribulations

    Science.gov (United States)

    Cameron, B. I.; Ketter, B. S.; Karakis, S.

    2012-12-01

    Nova Scotia, strategically located on Canada's east coast, is an emerging wine region, whose distinctive wines are garnering international acclaim. Nova Scotia has a long and rich tradition of growing grapes for wine dating back as far as 1611. Nova Scotia's mesoclimates, glacial soils, and proximity to the Atlantic Ocean form a complex alliance to create a unique and expressive terroir. Tidal Bay is a new appellation wine for Nova Scotia stylistically defined as a fresh, crisp and high-acid blend of white grapes. There are four main wine-growing regions in Nova Scotia, all influenced by the warming effects of the Bay of Fundy and Atlantic Ocean: Malagash Peninsula, Annapolis Valley, Bear River Valley and the South Shore. Nova Scotia currently has 14 producing wineries with many more in the development stage. Nova Scotia grape growers not only have had success developing mature and consistent hybrids, but in recent years several vinifera have flourished in this cool climate area. The white hybrids include L'Acadie Blanc, New York Muscat, Seyval Blanc, and Vidal Blanc. The white vinifera include chardonnay, riesling, pinot gris, and sauvignon blanc. Red hybrids are Baco Noir, Leon Millet, Lucie Kuhlmann, and Marechal Foch, whereas the only red vinifera is pinot noir. Nova Scotia has nearly perfect climatic conditions for making world class icewines and sparkling wines. A preliminary GIS analysis of climate, topographic, geology and soil data helps to define Nova Scotia's terroir. Annual precipiatation varies from 10 to 21.6 cm/year with a vast majority of the wineries located in regions with the lowest rainfall. Daily average temperature ranges from 5.5 to 7.5°C, degree growing days above 5°C from 1382 to 1991, and mean August temperature from 15.6 to 19.3 °C. Wineries cluster in the warmest regions based on these temperature measures to assist grape ripening. Soils in these diverse wine regions can range from silty, sandy and clay loams to more gravel-rich sandy

  7. Evolution of power plant foundations in Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Chen, C.T.; Larade, M.; Myette, R.; MacIvor, T. [Nova Scotia Power Inc., Halifax, NS (Canada)

    2009-07-01

    Many thermal steam plants in Nova Scotia, including the first 3 units Dartmouth's Tufts Cove Generating Station, were constructed on bedrock and near the sea for easy access to cooling water. Major equipment foundations such as turbine/condenser foundations, boiler feed pump foundations and fan foundations are concrete block foundations that are designed to withstand the heavy equipment and environmental loads imposed throughout the service-life of the plant. This paper discussed the rationale for choosing different types of foundations at the 5 power generating units at the Tufts Cove Generating Station. Due to the presence of boulders, pipe piles were installed in drilled holes in 1995 for the unit 2 precipitator foundation. In 2005, micro-piles were installed for unit 1 and 3 precipitators because they were relatively non-protrusive for the congested urban site that was full of buried structures and services. Similarly, for the unit 4 and 5 sound wall foundations, the high resistance capacities for both downward and uplift loads of the micro-piles embedded into the bedrock proved to be very valuable. These tall wall structures are subject to very high wind loads and were constructed at a geotechnically challenged site. Good geotechnical investigation and consultation was shown to be the basis for good design and construction of foundation works. It was concluded that the lessons learned at Tufts Cove can be applied to other similar foundation designs. 7 refs., 10 figs.

  8. Energy conservation on Nova Scotia farms: Baseline energy data

    International Nuclear Information System (INIS)

    Bailey, J.A.; Gordon, R.; Burton, D.; Yiridoe, E.K.

    2008-01-01

    Direct energy use is a small but essential component of the farm greenhouse gas (GHG) budget. Improvements in energy efficiency and renewable energy can help reduce farm operating costs, improve air quality and reduce GHG emission levels. Energy conservation is especially important in Nova Scotia (NS), Canada, where fossil fuels, particularly coal, remain the primary source of electrical generation. Responses from mail surveys were used to establish baseline data on a cross-section of NS farms with respect to direct energy costs and usage to demonstrate differences in farm type and size. A 32% (N=224) response rate was achieved. Based on this survey, the average energy bill for a NS farm in 2004 was $11,228, with most (61.7%) of their energy cost attributable to the purchase of petroleum products. Almost all farmers (96.4%) indicated that their energy cost was a primary concern. Farmers identified the operation of vehicles and mobile equipment, as well as lighting and heating as having the greatest energy requirements in their operations. Energy usage varied with farm type and size. NS farms consumed 1.2 petajoules of energy equivalent to 127 kilotonnes of CO 2 with 52.7% of emissions from electricity use in 2004

  9. Water resource management : a strategy for Nova Scotia

    International Nuclear Information System (INIS)

    Theakston, J.

    1998-01-01

    Since 1995, the Nova Scotia Department of the Environment has been the lead agency responsible for water resource management in the province. The agency's mandate has been to establish a water resource management strategy and to report periodically to the people of the province on the state of the environment, including air, water and waste resource management. One of the Department's goals is to ensure that surface and groundwater resources are being adequately protected. This paper summarizes issues related to dams and how they will be addressed. The Department allocates water through approvals and regulates use and alteration of watercourses. The construction of a dam and water withdrawal for municipal, industrial, hydroelectric or other purposes requires an approval. The major concerns with these activities are flows to sustain downstream habitat, competing demand for water, public safety, and water quality impacts. The main water management actions established under the water strategy involve: (1) geo-referencing water resource use and allocation, (2) protecting water quality, (3) integrating management of natural resources, and (4) promoting partnership in stewardship

  10. Environmental assessment of exploration drilling off Nova Scotia: executive summary

    International Nuclear Information System (INIS)

    2000-01-01

    The environmental assessment project of drilling offshore Nova Scotia covers year-around drilling conducted from jackup rigs, semi-submersible rigs, and drill ships that use the methods described in the project description on the Scotian Shelf, the Laurentian Channel and St, Pierre Bank. The assessment was sponsored by all the oil companies active in the area, namely Mobil Oil Canada, Shell Canada, Imperial Oil Resources, Gulf Canada Resources, Chevron Canada Resources, PanCanadian Petroleum, Murphy Oil Company and Norsk Hydro Canada Oil and Gas. This summary describes the impact assessment methodology used, provides a description of the project, reviews the cumulative impact, and the impacts of discrete activities such as noise and disturbances, operational discharges of oil, disruption of the benthos, garbage and waste disposal, and accidental oil spills, and outlines mitigation and monitoring activities to deal with the impacts. Mitigation measures encompass routine discharges, accidental oil spills, spill response, monitoring activities, contingency plans and an overall environmental protection plan. In addition to this generic assessment, the consultants recommend that individual exploration drilling programs that fall outside of the parameters outlined in the generic environmental assessment document, be required to undergo a program-specific assessment that focuses on those aspects of the proposed program that differ from the parameters prescribed in the present document. 9 refs

  11. Weather impacts on leisure activities in Halifax, Nova Scotia

    Science.gov (United States)

    Spinney, Jamie E. L.; Millward, Hugh

    2011-03-01

    The aim of this study was to investigate the impact of daily atmospheric weather conditions on daily leisure activity engagement, with a focus on physically active leisure. The methods capitalize on time diary data that were collected in Halifax, Nova Scotia to calculate objective measures of leisure activity engagement. Daily meteorological data from Environment Canada and daily sunrise and sunset times from the National Research Council of Canada are used to develop objective measures of the natural atmospheric environment. The time diary data were merged with the meteorological data in order to quantify the statistical association between daily weather conditions and the type, participation rate, frequency, and duration of leisure activity engagement. The results indicate that inclement and uncomfortable weather conditions, especially relating to thermal comfort and mechanical comfort, pose barriers to physically active leisure engagement, while promoting sedentary and home-based leisure activities. Overall, daily weather conditions exhibit modest, but significant, effects on leisure activity engagement; the strongest associations being for outdoor active sports and outdoor active leisure time budgets. In conclusion, weather conditions influence the type, participation rate, frequency, and duration of leisure activity engagement, which is an important consideration for health-promotion programming.

  12. Expanding Pharmacists' Scope of Practice to Include Immunization in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Beth O'Reilly

    2017-07-01

    Full Text Available On 10 December 2010 An Act to Amend Chapter 36 of the Acts of 2001, the Pharmacy Act (Bill 7 received Royal Assent in Nova Scotia, including an amendment that enabled an expanded scope of pharmacy practice. Expanding pharmacists' scope of practice came about from recommendations by various federal and provincial government bodies as an attempt to improve accessibility to health care and decrease costs. In 2013, pharmacists in Nova Scotia began administering the influenza vaccine as part of the publicly funded program in attempts to improve vaccine coverage rates. Preliminary evaluation in Nova Scotia has shown an increase in influenza vaccination coverage. Although pharmacist administration of influenza vaccination may improve vaccination coverage and reduce demand on physician time, there may be tension created among the professions, which needs to be addressed and managed.

  13. Evaluation of petroleum products pricing regulation in Nova Scotia : a 2 year review

    International Nuclear Information System (INIS)

    2008-11-01

    Gasoline price regulation was introduced in Nova Scotia on July 1st, 2006. This report presented the findings and recommendations of a review of the first two years of the gasoline price regulation in Nova Scotia. The regulations had three main objectives. This review examined whether, and to what extent, they were achieved. The objectives were to stabilize price, maintain industry infrastructure, and minimize cost to consumers. The report described the rationale for the regulation, study objectives, and approach taken to gasoline regulation in Nova Scotia, including the objectives and technical aspects of how regulation works. The gasoline market in Nova Scotia was examined, including the market structure and competitive behaviour in an unregulated market. The report also provided some theoretical perspectives on how regulation was likely to affect industry structure and competitive behaviour. The extent to which the regulation was meeting its objectives was then assessed and perspectives on the regulation from consumers, retailers and wholesalers were offered. Last, the report provided a review of the findings in terms of the key elements of regulatory design and set out recommendations for improving the system. It was recommended that in order to improve certainty, particularly given the regulated price differences amongst grades, the regulations should be amended to include grade specifications referencing octane ratings. tabs., figs

  14. Regional Patterns of Ethnicity in Nova Scotia: A Geographical Study. Ethnic Heritage Series, Volume VI.

    Science.gov (United States)

    Millward, Hugh A.

    In this sixth volume of the Ethnic Heritage Series, the pattern of ethnicity in Nova Scotia (Canada) is examined by deriving indices of diversity for counties and larger towns. The historical development of ethnic patterns from 1767 to 1971 and recent changes in the ethnic pattern are discussed. Ethnic origin data is mapped for 1871 and 1971 and…

  15. Consultation paper : Nova Scotia's renewed energy strategy and climate change action plan

    International Nuclear Information System (INIS)

    2007-10-01

    The Nova Scotia Department of Energy is seeking to create a sustainable and prosperous Nova Scotia that is responsive to climate change. The purpose of this report was to inform public discussion around two upcoming documents, namely the renewed energy strategy focusing on broad energy policy and a climate change action plan for Nova Scotia to reduce greenhouse gas emissions. The report discussed mitigation measures, as it is closely tied with energy use. The consultation process to inform the two documents was to include public forums and direct stakeholder consultation. The report discussed Nova Scotia's strategy for dealing with climate change and the world of energy. Recent changes in energy prices, exploration, awareness, and emerging but uncertain technologies were presented. Long term planning and a review of policy changes were also addressed. The report also presented options for a renewed energy strategy and discussed air quality; energy conservation and efficiency; electricity; natural gas; energy opportunities; government action; and government intervention. Submissions were also sought as input to the discussion paper. refs., tabs., figs., appendices

  16. Canada-Nova Scotia Offshore Petroleum Board annual report, 1992-1993

    International Nuclear Information System (INIS)

    1993-06-01

    The Canada-Nova Scotia Offshore Petroleum Board was established as the agency responsible for the regulation of the hydrocarbon resources in the Nova Scotia offshore. The Board evaluates resource potential, administers petroleum exploration and production rights, approves offshore activities, and approves benefits and development plans. The main activities of the Board in 1992-1993 are summarized and financial statements are presented. Highlights include production of 572,300 m 3 of oil during the first production season of LASMO Nova Scotia Ltd.'s Cohasset development, the first commercial offshore oil production for Canada; four major resource evaluation projects in the Glenelg Field, the Laurentian sub-basin, the Fundy Rift Basin, and the Panuke Field; holding of discussions between Nova Scotia, Newfoundland, and Canada on the maritime boundary lines between respective offshore petroleum board jurisdictions, in the wake of a June 1992 determination of the disputed maritime boundary around St. Pierre et Miquelon; and amendments of certain safety-related legislation applicable to offshore operations. Employment benefits of the Cohasset project during 1992 totalled ca 470 Nova Scotians and 120 other Canadians. 3 tabs

  17. Herself: Elle-Meme. Report of the Nova Scotia Task Force on the Status of Women.

    Science.gov (United States)

    Nova Scotia Task Force on the Status of Women, Halifax.

    This report to the Canadian Government from the Nova Scotia Women's Task Force examines the social issues and problems pertaining to the women's movement in that province. Discussions are provided on the situations and attitudes toward homemakers, working women, marriage, divorce, child care, education, health, and political participation.…

  18. Creating Cohesive Community Through Shared Reading: A Case Study of One Book Nova Scotia

    Directory of Open Access Journals (Sweden)

    Alyssa Harder

    2015-06-01

    Full Text Available One Book Nova Scotia is described on the program’s website as “a province-wide community reading event for adults.” Formally programmed events have included the book announcement and launch, a series of author readings, and book discussions, both face to face and through Twitter. This paper analyzes the success of the One Book Nova Scotia program in achieving its goals of developing a reading culture and community in the province of Nova Scotia based on the findings of a participant survey, distributed in both 2012 and 2013, and an analysis of the 2013 Twitter discussion. This analysis reveals that participants tended to be well-educated females, aged 50-59, and often employed in libraries, bookselling or publishing, or news media. The goal of developing or participating in a reading community was a compelling motivator for many respondents. Although many respondents indicated their desire to be part of a reading community, Twitter was not proven to be an effective forum for fostering conversation or debate related to One Book Nova Scotia. Building on the analysis, the paper concludes with some recommendations to improve the effectiveness of future programs. These recommendations include the selection of a book with strong regional connections, an expansion of publicity methods, an increase in lead time between the announcement of the book title and the start of programming, and a more strategic use of Twitter as a discussion forum. Although these recommendations arise from the specific analysis of the One Book Nova Scotia reading program, they are general enough to apply to other One Book, One Community programs.

  19. A Hydrographic Survey of the Scotia Sea, 15 March 1999 to 22 April 1999 (NODC Accession 0000861)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — CTD and chemical data were collected using CTD and bottle casts in the Drake Passage and Scotia Sea from the JAMES CLARK ROSS. Data were collected from 15 March 1999...

  20. More than wind: evaluating renewable energy opportunities for First Nations in Nova Scotia and New Brunswick

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Diana [MREM Canada (Canada)

    2011-04-15

    The Nova Scotia and New Brunswick governments have committed to developing the renewable energy sector in the coming years. However, due to a lack of information, First Nations are not familiar with renewable energy technologies and their economic opportunities. The aim of this paper is to provide First Nations with information on the different renewable energies. It has been noticed that First Nations have not seized either the opportunities offered by the Nova Scotia feed-in tariff nor the New Brunswick community energy policy and an overview of these policies is provided. In addition, information on renewable energy technologies is presented along with potential opportunities specific to each First Nation in the 2 provinces. This paper provides First Nations with useful information on renewable energy and with recommendations for immediate and long term action; it is expected that this document will result in a greater involvement of First Nations in the renewable energy sector.

  1. Persistence, biodegradation and biological impact of Bunker C residues in Black Duck Cove, Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Lee, K.; Wohlgeschaffen, G. D.; Tremblay, G. H. [Dept. of Fisheries and Oceans of Canada, Inst. Maurice-Lamontagne, Mont Joli, PQ (Canada); Vandermeulen, D. C.; Mossman, K. G. [Dept. of Fisheries and Oceans of Canada, Bedford Inst. of Oceanography, Dartmouth, NS (Canada); Doe, K. G.; Jackman, P. M. [Environment Canada, Environmental Science Center, Moncton, NB (Canada); Prince, R. C.; Garrett, R. M.; Haith, C. E. [Exxon Research and Engineering Company, Annandale, NJ (United States)

    1998-12-31

    In 1970, approximately 2,045 cubic metres of Bunker C oil impacted on 300 km of Nova Scotia`s coastline following the grounding of the tanker `Arrow`. Only 10 per cent of the coastline was subjected to cleanup, the remainder was left to degrade naturally. Samples of sediments were collected in 1993 and 1997 in order to assess the attenuation processes on the reduction of toxicity within sediments and interstitial waters at Black Duck Cove, one of the untreated sites where residual oil was clearly evident. Detailed chemical analyses showed that the Bunker C oil at this site has undergone substantial biodegradation. Over the 20 plus years since the oil spill the toxicity of the residual oil has been significantly reduced and there is substantial evidence of habitat recovery.

  2. Proceedings of Nova Scotia's 2006 energy research and development forum

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    The Nova Scotia 2006 energy research and development forum provided a venue for experts from industry, research institutions and government to discuss how research and development will shape the future of energy in the province. The forum was divided into 3 sessions: (1) building knowledge about the marine environment, (2) building knowledge about geoscience, and (3) building knowledge about sustainable energy. A wide ranges of issues related to the Nova Scotia region included whale identification; fisheries mapping; the commercialization of hydrocarbon discoveries; carbon capture and storage and petroleum system analysis and prospect evaluation. Keynote addresses were presented on produced water in Norway; deepwater exploration in Morocco; renewable energy and Canada's role as an energy superpower. The conference featured more than 57 presentations, of which 4 have been catalogued separately for inclusion in this database. refs., tabs., figs.

  3. Province of Nova Scotia Electricity Marketplace Governance Committee First Interim Report

    International Nuclear Information System (INIS)

    2002-12-01

    This report summarizes the group discussions of the Electricity Marketplace Governance Committee's (EMGC) over the past 6 months regarding the implementation of new rules for power competition in Nova Scotia's electricity market. Emphasis has been placed on external influences, defining the size and form of the short-term competitive portion of the Nova Scotia market, and a detailed consideration of the current transmission system and the changes needed to achieve a sustainable, world class energy sector that would enhance the quality of life for Nova Scotians. The report provides recommendations regarding how competition can be encouraged. The main drivers for electricity restructuring have been energy efficiency, risk-allocation, reliability, environmental impact, and consumer protection. The external influences on the Nova Scotia electricity market include: (1) economics of electricity restructuring, (2) the Federal Energy Regulatory Commission, (3) New Brunswick and electricity restructuring, and (4) Nova Scotia and the energy strategy. This report described the market scope and basic market model with reference to bilateral contract market, fully competitive wholesale pool market, and a single buyer market. The transmission issues discussed in this report included the importance of transmission, transmission tariff options, transmission services offered, design issues, and congestion management policies. The EMGC was directed to examine market design issues to accommodate an Open Access Transmission Tariff (OATT). As such, this report identifies some transmission issues that must be resolved to implement tariffs, and conditions of access to the transmission system and its impact on open access market design. The final report is expected to be available in March 2003

  4. Diatoms as an indicator of bottom surface sediment dynamics in the southern Scotia sea

    Directory of Open Access Journals (Sweden)

    Олег Сергеевич Огиенко

    2015-05-01

    Full Text Available The study of diatoms from the sediments of the lower interval of column K97-18 in Scotia Sea it is revealed the combination of Late-Holocene and Miocene species in complexes, due to the abundance of inclusions of Middle Miocene diatoms in the rock. Age of re-deposition, transporters and ways of transportation are determined, and it is suggested possible localization of diatomite layers

  5. The ambient air quality accounts for the Nova Scotia Genuine Progress Index

    International Nuclear Information System (INIS)

    Monette, A.; Colman, R.

    2004-01-01

    The Nova Scotia Genuine Progress Index (GPI) is a measure of sustainable development which provides a complete and accurate picture of our well-being as a society. The GPI assigns explicit values to environmental quality, population health, livelihood security, equity, free time, and educational attainment. The Nova Scotia GPI includes 22 social, economic and environmental components, including ambient air quality. This report investigates Nova Scotia's ambient air concentrations and emissions of carbon monoxide (CO), total particulate matter (PM), sulphur dioxide (SO 2 ), nitrogen oxides (NOx), and volatile organic compounds (VOC). The costs of damages caused by the these key air pollutants are also examined. Exposure to these pollutants results in negative impacts on human health, damage to materials, agricultural crops and changes in forest productivity. From 1979 to 1996, national ambient concentrations of each of these pollutants decreased significantly. However, the national average concentration of ground-level ozone increased by 34 per cent during the same time period. In Nova Scotia, concentrations of CO, PM and SO 2 have declined dramatically since 1979, but the trends for NO 2 and ground-level ozone do not show significant declines. On a per capita basis, SOx emissions from electric power generation in the province are more than 8 times the Canadian average. The province also had higher per capita emissions of CO, PM, SOx and VOCs than all reporting OECD countries. Electric power generation is the greatest source of fuel combustion emissions in the province, followed by industrial and transportation sources. This report also described some individual actions that can be taken to reduce air pollutant emissions. 174 refs., 37 tabs., 60 figs

  6. Clinical characteristics, treatment and outcome of children with Lyme arthritis in Nova Scotia.

    Science.gov (United States)

    Glaude, Pier Diane; Huber, Adam M; Mailman, Timothy; Ramsey, Suzanne; Lang, Bianca; Stringer, Elizabeth

    2015-10-01

    Lyme disease is an emerging problem in Nova Scotia. Lyme arthritis is a late manifestation of Lyme disease. To describe the demographic characteristics, referral patterns and clinical course of children diagnosed with Lyme arthritis in a tertiary care pediatric rheumatology clinic in Nova Scotia. In the present retrospective chart review, subjects diagnosed with Lyme arthritis between 2006 and 2013 were identified through the clinic database. Demographic variables, referral patterns, clinical presentation and information regarding treatment course and outcome were collected. Seventeen patients were identified; 76% presented in 2012 and 2013. In 37.5% of cases, the referring physician suspected Lyme disease. Most patients presented with one or more painful and/or swollen joints; 94% had knee involvement. Only three of 17 patients had a history of erythema migrans and four of 17 recalled a tick bite. Five patients had a history of neurological manifestations consistent with Lyme disease, although, none had a diagnosis made at the time. Arthritis usually resolved after treatment with standard antibiotics; however, at last follow-up, two patients had antibiotic refractory Lyme arthritis, with one having joint damage despite aggressive arthritis treatment. A significant increase in cases of Lyme arthritis has recently been recognized in a pediatric rheumatology clinic in Nova Scotia. A history of a tick bite or erythema migrans were not sensitive markers of Lyme arthritis, and this diagnosis was often not considered by the referring physician. Educational initiatives should be undertaken to increase local awareness of this treatable cause of arthritis in children.

  7. Petroleum products price regulation in Nov Scotia : a six-month review

    International Nuclear Information System (INIS)

    2007-03-01

    Gasoline pricing regulation was introduced in July 2006 in order to achieve the following 3 main objectives: (1) stabilize prices by reducing the frequency of price changes and creating more uniform pricing across the province, (2) maintain industry infrastructure by slowing or halting the decline in the dealer network, particularly in rural areas, by improving viability through regulated margins, and (3) minimize the cost to consumers since higher prices are expected to result from the actions needed to maintain price stability and the higher margins needed to maintain industry infrastructure. This report examined the extent to which these objectives were achieved and contained the findings and recommendations of a review of the first six months of gasoline price regulation in Nova Scotia. The report discussed the rationale for regulation, study objectives, approach, and warning signs. It also discussed gasoline regulation in Nova Scotia including how regulation works and implementing regulation. The Nova Scotia gasoline market was presented with reference to industry structure; pre-regulation competition and pricing; and how regulation may affect structure and competition. Last, the report discussed whether regulation was meeting the objectives and perspectives on regulation. Several recommendations were presented, such as reducing the benchmark price adjustment period from two weeks to one week; removing the price cap on full-serve gasoline; adopting a fixed and transparent formula for forward averaging and applying it at each adjustment; and considering a framework for regulatory review. 12 refs., 15 figs

  8. On the Antarctic Slope Front and Current crossing of the South Scotia Ridge

    Science.gov (United States)

    Orsi, A. H.; Palmer, M.; Gomis, D.; Flexas, M. M.; Kim, Y.-S.; Jordà, G.; Wiederwohl, C.; Álvarez, M.

    2012-04-01

    To unveil the contorted path followed by the Antarctic Slope Current connecting the Weddell and Scotia Seas, hydrographic stations with unprecedented spatial resolution were occupied on a series of sections across the slope and multiple channels in the double-pronged western portion of the South Scotia Ridge. Fieldwork consisted of two cruises from the ESASSI (January 2008) and ACROSS (February 2009) programs, the Spanish and USA/Argentina components of the International Polar Year core project SASSI (Synoptic Antarctic Shelf-Slope Interaction study). In this region the Antarctic Slope Current can be located by the pronounced in-shore deepening of isopycnals over the continental slope, rendering the strong subsurface temperature and salinity gradients characteristic of the Antarctic Slope Front. Before reaching the gaps in the southern Ridge near 51°W and 50°W, the ASC carries about 3 Sv of upper layer waters, but it splits into shallow and deep branches upon turning north through these two gaps. The shallower branch enters the Hesperides Trough at 51°W, then shows a tight cyclonic loop back to that longitude roughly following the slope's 700-m isobath, and turns again westward through a similar gap in the northern Ridge. In the Scotia Sea the westward-flowing Antarctic Slope Current is found as far west as the Elephant Island along slightly deeper levels of slope (1100 m) before it is blocked by the Antarctic Circumpolar Current south of the Shackleton Fracture Zone (56°W). The deeper branch of the ASC in the Powell Basin crosses the southern Ridge near 50°W and roughly follows the 1600-m isobath before entering the Scotia Sea through the Hesperides Gap farther to the east (49°W). Thereafter the deeper waters carried westward by this branch become undistinguishable from those circulating farther offshore. Repeat cross-slope sections at both southern and northern flanks of the South Scotia Ridge showed significant temporal variability in the characteristics

  9. Modelling hydrological conditions in the maritime forest region of south-western Nova Scotia

    Science.gov (United States)

    Yanni, Shelagh; Keys, Kevin; Meng, Fan-Rui; Yin, Xiwei; Clair, Tom; Arp, Paul A.

    2000-02-01

    Hydrological processes and conditions were quantified for the Mersey River Basin (two basins: one exiting below Mill Falls, and one exiting below George Lake), the Roger's Brook Basin, Moosepit Brook, and for other selected locations at and near Kejimkujik National Park in Nova Scotia, Canada, from 1967 to 1990. Addressed variables included precipitation (rain, snow, fog), air temperature, stream discharge, snowpack accumulations, throughfall, soil and subsoil moisture, soil temperature and soil frost, at a monthly resolution. It was found that monthly per hectare stream discharge was essentially independent of catchment area from interception and soil percolation.

  10. The electrification of Nova Scotia, 1884--1973: Technological modernization as a response to regional disparity

    Science.gov (United States)

    King, Lionel Bradley

    This dissertation investigates local attempts to use technology as a force for regional rehabilitation in the economically-depressed Maritime region of Canada. At the time of Confederation in 1867, the Maritime province of Nova Scotia was prosperous, progressive, and cultured. By the end of the 1910s, the province had entered a long period of economic and social decline. Recent historiography has shown that, far from passively accepting their fate, Nova Scotians and other Maritimers, actively resisted marginalization with political, cultural, or social action. The thesis expands upon that literature by exploring technology-based strategies of provincial rehabilitation using Thomas P. Hughes's systems perspective and David E. Nye's semiotic approach. In doing so, it applies methods from the social constructivist school of the history of technology to the larger concerns of Maritime Canadian historiography. In large part, the North American culture of technology determined the ways in which Nova Scotians applied technological solutions to provincial concerns. Technology has long been central to the Western idea of progress. As the "high technology" of the late nineteenth and early twentieth centuries, electricity reinforced that view: its ephemeral nature and silent efficiency led people to endow it with transformative, even mystical, powers. As a result, Nova Scotians, adopted a program of electrical modernization in the late 1910s as a remedy for regional disparity. The Nova Scotia government's first step was the creation of an Ontario-style hydroelectric commission designed to bring order to the province's fragmented and inefficient electrical network. Over the next few decades, the Nova Scotia Power Commission implemented rural electrification, home modernization, and regional system-building models that had already proven successful in Ontario and the United States. The system-building philosophies behind these programs were adapted to local conditions and

  11. Environmental and public interface for Point Aconi generating station, Point Aconi, Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Toner, T P

    1993-01-01

    Nova Scotia Power's most recent generating station is a 165 MW coal-fired circulating fluidized bed (CFB) unit located at Point Aconi on the northern tip of Boularderie Island. This paper discusses the environmental and public interfaces associated with this project, particularly on the unique items and issues requiring delicate and/or innovative approaches for their successful completion. Specific issues discussed include clarification of the process, the turnkey arrangement, the community liaison committee, freshwater supply, air emissions and dealings with commercial growers, dealings with lobster fishermen, dealings with Native peoples, and the transmission line.

  12. Internationally Educated Female Teachers who have Immigrated to Nova Scotia: A Research/Performance Text

    Directory of Open Access Journals (Sweden)

    Susan C. Walsh

    2007-09-01

    Full Text Available This research/performance text emerged from a study involving internationally educated female teachers who have immigrated to Atlantic Canada. The text features the words and artwork of the research participants as well as excerpts from newspapers, academic writing, and documents about immigration in Nova Scotia juxtaposed so as to foreground the complexity of the women's immigration and integration experiences. Introductory comments provide contextual information about the research project, the participants, and the evolution of, as well as rationale for, the text as performance piece.

  13. "I feel like I am surviving the health care system": understanding LGBTQ health in Nova Scotia, Canada.

    Science.gov (United States)

    Colpitts, Emily; Gahagan, Jacqueline

    2016-09-22

    Currently, there is a dearth of baseline data on the health of lesbian, gay, bisexual, transgender, and queer (LGBTQ) populations in the province of Nova Scotia, Canada. Historically, LGBTQ health research has tended to focus on individual-level health risks associated with poor health outcomes among these populations, which has served to obscure the ways in which they maintain their own health and wellness across the life course. As such, there is an urgent need to shift the focus of LGBTQ health research towards strengths-based perspectives that explore the complex and resilient ways in which LGBTQ populations promote their health. This paper discusses the findings of our recent scoping review as well as the qualitative data to emerge from community consultations aimed at developing strengths-based approaches to understanding and advancing LGBTQ pathways to health across Nova Scotia. Our scoping review findings demonstrated the lack of strengths-based research on LGBTQ health in Nova Scotia. Specifically, the studies examined in our scoping review identified a number of health-promoting factors and a wide variety of measurement tools, some of which may prove useful for future strengths-based health research with LGBTQ populations. In addition, our community consultations revealed that many participants had negative experiences with health care systems and services in Nova Scotia. However, participants also shared a number of factors that contribute to LGBTQ health and suggestions for how LGBTQ pathways to health in Nova Scotia can be improved. There is an urgent need to conduct research on the health needs, lived experiences, and outcomes of LGBTQ populations in Nova Scotia to address gaps in our knowledge of their unique health needs. In moving forward, it is important that future health research take an intersectional, strengths-based perspective in an effort to highlight the factors that promote LGBTQ health and wellness across the life course, while taking

  14. “I feel like I am surviving the health care system”: understanding LGBTQ health in Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Emily Colpitts

    2016-09-01

    Full Text Available Abstract Background Currently, there is a dearth of baseline data on the health of lesbian, gay, bisexual, transgender, and queer (LGBTQ populations in the province of Nova Scotia, Canada. Historically, LGBTQ health research has tended to focus on individual-level health risks associated with poor health outcomes among these populations, which has served to obscure the ways in which they maintain their own health and wellness across the life course. As such, there is an urgent need to shift the focus of LGBTQ health research towards strengths-based perspectives that explore the complex and resilient ways in which LGBTQ populations promote their health. Methods This paper discusses the findings of our recent scoping review as well as the qualitative data to emerge from community consultations aimed at developing strengths-based approaches to understanding and advancing LGBTQ pathways to health across Nova Scotia. Results Our scoping review findings demonstrated the lack of strengths-based research on LGBTQ health in Nova Scotia. Specifically, the studies examined in our scoping review identified a number of health-promoting factors and a wide variety of measurement tools, some of which may prove useful for future strengths-based health research with LGBTQ populations. In addition, our community consultations revealed that many participants had negative experiences with health care systems and services in Nova Scotia. However, participants also shared a number of factors that contribute to LGBTQ health and suggestions for how LGBTQ pathways to health in Nova Scotia can be improved. Conclusions There is an urgent need to conduct research on the health needs, lived experiences, and outcomes of LGBTQ populations in Nova Scotia to address gaps in our knowledge of their unique health needs. In moving forward, it is important that future health research take an intersectional, strengths-based perspective in an effort to highlight the factors that

  15. Measuring energy conservation on Nova Scotia (NS) farms: A 2004 to 2011 comparison

    International Nuclear Information System (INIS)

    Bailey, J.A.; Duinker, P.; Amyotte, P.; Adams, M.; Khan, F.

    2016-01-01

    Many jurisdictions, including Nova Scotia (NS), have implemented policies and programs around energy. The NS government has targeted energy efficiency and more renewable energy as two main policy areas. The NS Department of Agriculture has taken initiative to provide support to implement energy conservation, energy efficiency and renewable energy opportunities in recent years but have these programs and policies been effective? A baseline energy use survey was conducted in 2005 and responses from mail surveys in 2012 (n = 273, 11.4% response rate) were used to measure the change in NS farm energy use data reported for 2004 and 2011. There have been significant reductions in energy use on NS farms. On average, NS farmers spent $8790 on energy expenses in 2011 compared to $11,228 in 2004. Adjusting for inflation, this is a 32% decrease, despite energy commodity pricing increases beyond the inflation rate. This is likely due to a decrease in energy use and a shift from gasoline use to diesel use. By the end of 2012, 36.0% of NS farmers (more than 860) had received some level of support to evaluate their energy options. This includes 410 energy audits compared to only 36 by the end of 2005. - Highlights: • Nova Scotia farmers decreased their energy costs by 32% between 2004 and 2011. • Energy reductions were likely due to decreased energy use and a shift in fuel use. • An estimated 374 NS farms had an energy audit between 2005 and 2012.

  16. Examining a "Household" Model of Residential Long-term Care in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Janice Keefe

    2017-04-01

    Full Text Available In 2006, Nova Scotia began to implement its Continuing Care Strategy which was grounded in a vision of providing client-centered care for continuing care clients, including residents of nursing homes. Considerable evidence pointed to the benefits of the “household” model of care—which led the province to adopt the smaller self-contained household model as a requirement for owners/operators seeking to build government-funded new and replacement nursing homes. The specific goals of the reform (the adoption of the household model included increasing the proportion of single rooms, improving the home-likeness of the facility, and more generally, providing high-quality care services. The reform was influenced by recognition of the need for change, rapid population aging in the province, and strong political will at a time when fiscal resources were available. To achieve the reform, Nova Scotia Department of Health released two key documents (2007 to guide the design and operation of all new and replacement facilities procured using a request for proposal process: The Long Term Care Program Requirements and the Space and Design Requirements. Results from a research study examining resident quality of life suggest regardless of physical design or staffing approach high resident quality of life can be experienced, while at the same time recognizing that the facilities with “self-contained household” design and expanded care staff roles were uniquely supporting relationships and home-likeness and positively impacting resident quality of life.

  17. Observations on the Cave-Associated Beetles (Coleoptera of Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Moseley M.

    2009-07-01

    Full Text Available The cave-associated invertebrates of Nova Scotia constitute a fauna at a very early stage of post-glacial recolonization. TheColeoptera are characterized by low species diversity. A staphylinid Quedius spelaeus spelaeus, a predator, is the only regularlyencountered beetle. Ten other terrestrial species registered from cave environments in the province are collected infrequently. Theyinclude three other rove-beetles: Brathinus nitidus, Gennadota canadensis and Atheta annexa. The latter two together with Catopsgratiosus (Leiodidae constitute a small group of cave-associated beetles found in decompositional situations. Quedius s. spelaeusand a small suite of other guanophiles live in accumulations of porcupine dung: Agolinus leopardus (Scarabaeidae, Corticariaserrata (Latrididae, and Acrotrichis castanea (Ptilidae. Two adventive weevils Otiorhynchus ligneus and Barypeithes pellucidus(Curculionidae collected in shallow cave passages are seasonal transients; Dermestes lardarius (Dermestidae, recorded fromone cave, was probably an accidental (stray. Five of the terrestrial beetles are adventive Palaearctic species. Aquatic beetles arecollected infrequently. Four taxa have been recorded: Agabus larsoni (Dytiscidae may be habitual in regional caves; another Agabussp. (probably semivittatus, Dytiscus sp. (Dytiscidae, and Crenitis digesta (Hydrophilidae are accidentals. The distribution andecology of recorded species are discussed, and attention is drawn to the association of beetles found in a Nova Scotia “ice cave”.

  18. Nova Scotia electricity market : frameworks for renewable energy contracting and cogeneration contracting : discussion document

    International Nuclear Information System (INIS)

    2006-01-01

    The recent Electricity Marketplace Governance Committee of Nova Scotia report issued a number of recommendations regarding renewable and cogeneration sales to retail consumers, as well as recommendations for top-up, spill rates and back-up rates to complement the operation of independent generating facilities. This discussion paper examined issues which need to be addressed in order to implement the recommendations. The discussion paper also included recommendations relating to the purchase of cogeneration output by the Nova Scotia Power Inc. (NSPI) under long term power purchase agreements. The aim of the paper was to provide a basis for the further discussion of issues in preparation for the development of future rules and regulations. The first part of the document identified ways for buyers and sellers to arrange contracts, as well as issues that need to be addressed at the institutional level to enable arrangements. Options for financial contracts and physical contracts were reviewed.The second part of the document examined pricing issues in the context of both financial and physical contract arrangements. Resolutions for both sets of options were proposed. Energy pricing principles were reviewed, as well as various pricing options and issues related to the analysis of price requirements. It was concluded that in order to support the safe, reliable and economic supply of electricity, the design of the electricity market should enable maximum flexibility in contractual arrangements and facilitate competition in ways that do not harm other parties

  19. Ichthyophonus irregularis sp. nov. from the yellowtail flounder Limanda ferruginea from the Nova Scotia shelf.

    Science.gov (United States)

    Rand, T G; White, K; Cannone, J J; Gutell, R R; Murphy, C A; Ragan, M A

    2000-05-25

    A previously described unusual form of the protistan parasite Ichthyophonus, differing in morphological and developmental features from I. hoferi sensu Plehn & Mulsow, was recovered from yellowtail flounder Limanda ferruginea Storer from the Brown's Bank area of the Nova Scotia shelf. The nuclear gene encoding the rRNA of the small ribosomal subunit was amplified from this unusual form of Ichthyophonus using the polymerase chain reaction, sequenced and aligned with other eukaryote small subunit (ssu)-rDNAs. Inferred phylogenetic trees clearly show that its ssu-rDNA is distinct from those of 2 isolates of I. hoferi sensu Plehn & Mulsow from different hosts and geographical locations (herring in the North Sea, and yellowtail flounder from the Nova Scotia shelf). We consider the unusual form to be a separate species, I. irregularis. The occurrence of a second, distinct type of Ichthyophonus within a single host species raises the possibility that ichthyophoniasis could be produced by different (although related) pathogens, and in some cases, by concurrent infections of the two.

  20. Canada-Nova Scotia Offshore Petroleum Board Annual report 1998-1999

    International Nuclear Information System (INIS)

    1999-01-01

    The Canada-Nova Scotia Offshore Petroleum Board is responsible for ensuring safe working conditions for offshore petroleum activities, protecting the environment during offshore petroleum operations, and managing offshore petroleum resources. This annual report includes financial statements of the Board for the fiscal year ending March 31, 1999. The projects undertaken by the Board in 1998-1999 included a technical audit of the Sable Offshore Energy Project, a resource assessment of the area known as the 'Gully', and resolving a complication regarding publicly available resource data for calls for bids for NS98-1 and NS98-2. A list of exploration licences in place in the Nova Scotia Offshore area was presented. Their total work bid was just over $188 million. In 1998, the Board's exploration activity included the review and approval for nine seismic programs. The Board also continues to monitor the extended Cohasset Benefits Plan to cover the scope of PanCanadian's Exploratory Drilling Program. This report included statements of financial position, revenue and expenditure, changes in financial position, and notes to the financial statements including accounting policies, accounts receivable, deferred revenue and commitments. The report also admitted uncertainty due to the year 2000 issue. It stated that it is not possible to be certain that all aspects of the year 2000 issue affecting the Board will be fully resolved. tabs., figs

  1. Socio-economic factors and adolescent sexual activity and behaviour in Nova Scotia.

    Science.gov (United States)

    Langille, Donald B; Hughes, Jean; Murphy, Gail Tomblin; Rigby, Janet A

    2005-01-01

    Little is known about associations of adolescents' socio-economic status (SES) and their sexual activity and risk behaviours. This study examined these associations in Nova Scotia adolescents aged 15-19. Students at four high schools in northern Nova Scotia completed surveys examining relationships of family SES factors and: 1) sexual activity (having had vaginal or anal intercourse, intercourse before age 15 (early intercourse)); and 2) risk behaviours (use of contraception/condoms, number of partners and unplanned intercourse after substance use). Of students present when the survey was administered, 2,135 (91%) responded. Almost half (49%) had had vaginal intercourse, and 7% anal intercourse. In univariate analysis for young women, non-intact family structure and lower parental education were associated with having vaginal, anal and early intercourse. Female risk behaviours showed no significant univariate associations with SES. Young men had univariate associations of family structure, lower maternal education and paternal unemployment with early intercourse, and lower paternal education with anal intercourse. Condom use was higher for young men with employed fathers; those living with both parents less often had >1 sexual partner. In multivariate analysis, most SES associations with females' sexual activities held, while most for males did not, and few associations of SES and risk behaviours were seen for females. Indicators of lower SES are associated with sexual activity in young women. Sexual risk behaviours are not often associated with SES in females, though they are more so in males. These findings have implications for sexual health promotion and health services.

  2. Remarks of Honorable Eleanor Norrie, Minister of the Nova Scotia Department of Natural Resources at the 1996 CORE conference

    Energy Technology Data Exchange (ETDEWEB)

    Norrie, E.

    1996-10-01

    Speaking notes used by the Nova Scotia Minister of Natural Resources at the 1996 CORE Conference were provided. The presentation focused on the new Sable Offshore Energy Project, an important new offshore gas field being developed by Mobil Oil. The project represents a total investment of $3 billion, the biggest capital project ever undertaken in Nova Scotia, and is completely funded by the private sector. Nearly 4,000 jobs will be created during the offshore and onshore construction phase, as well as future tax revenues for the province, new business opportunities, infrastructure for future projects, and an estimated 11,000 `spin-off` jobs. To expedite the development process, the Government of Nova Scotia has recently established the Nova Scotia Offshore Energy Office to work exclusively on the Sable gas and pipeline project. Future plans include a gas processing plant for Guysborough County. The gas will be transported by pipeline across New Brunswick to the New England market. A proposal by Gaz Metropolitain is also expected which would have some of the gas transported to Quebec.

  3. Remarks of Honorable Eleanor Norrie, Minister of the Nova Scotia Department of Natural Resources at the 1996 CORE conference

    International Nuclear Information System (INIS)

    Norrie, E.

    1996-10-01

    Speaking notes used by the Nova Scotia Minister of Natural Resources at the 1996 CORE Conference were provided. The presentation focused on the new Sable Offshore Energy Project, an important new offshore gas field being developed by Mobil Oil. The project represents a total investment of $3 billion, the biggest capital project ever undertaken in Nova Scotia, and is completely funded by the private sector. Nearly 4,000 jobs will be created during the offshore and onshore construction phase, as well as future tax revenues for the province, new business opportunities, infrastructure for future projects, and an estimated 11,000 'spin-off' jobs. To expedite the development process, the Government of Nova Scotia has recently established the Nova Scotia Offshore Energy Office to work exclusively on the Sable gas and pipeline project. Future plans include a gas processing plant for Guysborough County. The gas will be transported by pipeline across New Brunswick to the New England market. A proposal by Gaz Metropolitain is also expected which would have some of the gas transported to Quebec

  4. Art Education, Romantic Idealism, and Work: Comparing Ruskin's Ideas to Those Found in Nineteenth Century Nova Scotia.

    Science.gov (United States)

    Amburgy, Patricia; Soucy, Donald

    1989-01-01

    Examines the relationship between romantic idealism and vocational goals of art education in nineteenth-century Nova Scotia, Canada. Compares these ideas with those of John Ruskin concerning art and morality. Discusses the views of the Nova Scotian educators relative to issues of contemporary art education. (KO)

  5. The ESASSI-08 cruise in the South Scotia Ridge region: Water masses, currents, and the ASF

    Science.gov (United States)

    Palmer, M.; Gomis, D.; Flexas, M. M.; Jordà, G.; Orsi, A. H.

    2009-04-01

    The ESASSI-08 oceanographic cruise carried out in January 2008 was the major milestone of ESASSI, the Spanish component of SASSI (a core project of the International Polar Year devoted to study the shelf-slope exchanges in different locations of Antarctica). The specific objectives of ESASSI, the sampling strategy and the overall distribution of the main variables across the 11 sections covered by the cruise are presented in a poster. Here we focus on three specific issues: i) the observation of strong tidal currents over some of the sampled slopes; ii) the path of the Antarctic Slope Front (ASF) over the SSR; and iii) the outflow of dense, ventilated water from the Weddell Sea into the South Scotia Sea. The main results are: i) Strong tidal currents with a significant diurnal component were observed over the southern slope of the SSR. Three tidal models are compared with the observations and used to de-tide ADCP currents. ii) The signature of the ASF is clearly detected on the southern slopes of the SSR (on the Weddell Sea flank). Over the northern slopes (the Scotia Sea flank), however, only weak signatures of frontal structures are observed; an in-depth biochemical analysis will be required to link the structures observed over the two flanks of the SSR. What seems clear is that the ASF does not extend further than Elephant Island, since southwestward of that island the shelf and the slope are fully occupied by Circumpolar Deep Water (CDW) from the Antarctic Circumpolar Current. iii) The shallower component of Weddell Sea Deep Water (Upper WSDW) flows over the SSR and pours into the Scotia Sea except to the east of Elephant Island, where the channels are less than 1500 m deep. The densest component of WSDW (Lower WSDW) is observed at both flanks of the SSR, but again a more detailed analysis of biochemical data will be required to prove a direct flux of this water mass across the SSR. Weddell Sea Bottom Water (WSBW) is not observed in any of the sampled sections.

  6. Detecting overpressure using the Eaton and Equivalent Depth methods in Offshore Nova Scotia, Canada

    Science.gov (United States)

    Ernanda; Primasty, A. Q. T.; Akbar, K. A.

    2018-03-01

    Overpressure is an abnormal high subsurface pressure of any fluids which exceeds the hydrostatic pressure of column of water or formation brine. In Offshore Nova Scotia Canada, the values and depth of overpressure zone are determined using the eaton and equivalent depth method, based on well data and the normal compaction trend analysis. Since equivalent depth method is using effective vertical stress principle and Eaton method considers physical property ratio (velocity). In this research, pressure evaluation only applicable on Penobscot L-30 well. An abnormal pressure is detected at depth 11804 feet as possibly overpressure zone, based on pressure gradient curve and calculation between the Eaton method (7241.3 psi) and Equivalent Depth method (6619.4 psi). Shales within Abenaki formation especially Baccaro Member is estimated as possible overpressure zone due to hydrocarbon generation mechanism.

  7. Persistence, biodegradation and biological impact of Bunker C residues in Black Duck Cove, Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Lee, K.; Wohlgeschaffen, G. D.; Tremblay, G. H. [Dept. of Fisheries and Oceans of Canada, Inst. Maurice-Lamontagne, Mont Joli, PQ (Canada); Vandermeulen, D. C.; Mossman, K. G. [Dept. of Fisheries and Oceans of Canada, Bedford Inst. of Oceanography, Dartmouth, NS (Canada); Doe, K. G.; Jackman, P. M. [Environment Canada, Environmental Science Center, Moncton, NB (Canada); Prince, R. C.; Garrett, R. M.; Haith, C. E. [Exxon Research and Engineering Company, Annandale, NJ (United States)

    1998-07-01

    In 1970, approximately 2,045 cubic metres of Bunker C oil impacted on 300 km of Nova Scotia's coastline following the grounding of the tanker 'Arrow'. Only 10 per cent of the coastline was subjected to cleanup, the remainder was left to degrade naturally. Samples of sediments were collected in 1993 and 1997 in order to assess the attenuation processes on the reduction of toxicity within sediments and interstitial waters at Black Duck Cove, one of the untreated sites where residual oil was clearly evident. Detailed chemical analyses showed that the Bunker C oil at this site has undergone substantial biodegradation. Over the 20 plus years since the oil spill the toxicity of the residual oil has been significantly reduced and there is substantial evidence of habitat recovery.

  8. Remote assessment of instantaneous changes in water chemistry after liming in a Nova Scotia catchment

    Science.gov (United States)

    Angelidis, Christine

    2013-04-01

    Remote assessment of instantaneous changes in water chemistry after liming in a Nova Scotia catchment ANGELIDIS, C.1, STERLING, S.1, BREEN, A.2, BIAGI, K.1., and CLAIR, T.A.1 1Dalhousie University, christine.angelidis@dal.ca, 2Bluenose Coastal Action Foundation, andrew@coastalaction.org Southwestern Nova Scotia has some of the most acidic freshwaters in North America due to its location downwind of the major emission sources in eastern Canada and the US and due to a resistant geology which offers little acid buffering capacity (Clair et al. 2007). Because of the poor buffering and regionally high runoff values, hydrological events such as snowmelt and rain storms are frequent and can cause sudden changes in water chemistry which can have devastating effects on freshwater biota due to increases in acidity and metals (Dennis and Clair in press). Clair et al. (2001) have estimated the potential frequency of acidic episodes in this region based on a number of hydrological factors, though the technology available at the time to monitor short-term changes was not dependable. Recent advances in equipment have made the assessment of the frequency and severity of acidic episodes easier and more accurate, allowing better interpretation and prediction of hydrogeochemical changes with variations in weather and deposition patterns. Here we take advantage of these recent advances to monitor water chemistry in an experimental catchment, and explore the response to catchment liming. Catchment liming is one way of mitigating the effects of acid deposition in sensitive areas. We limed a 50 ha catchment at a rate of 5 t/ha in the Gold River watershed of southwest Nova Scotia to examine the interactions between application of lime with the geological and climatological conditions of this region and acid episode frequency. In order to assess changes of episode frequency caused by liming, we established two mobile environmental monitoring platforms in the catchment: a control site

  9. Nova Scotia's solid waste-resource management strategy

    Energy Technology Data Exchange (ETDEWEB)

    Friesen, B. [Nova Scotia Dept. of the Environment, Halifax, NS (Canada)

    2000-07-01

    The efforts that the province of Nova Scotia has made to establish a sustainable economy and environment were discussed. In 1989, the province of 930,000 people generated about 630,000 tonnes of municipal waste annually. At the time, there were no recycling or recovery facilities. The province's 1995 Solid Waste-Resource Management Strategy has changed this around with the following key measures: a commitment to 50 per cent diversion of solid waste by 2000, regionalisation to optimize costs, an expanded deposit-refund system for all beverage containers, increased disposal standards for landfilling/incineration, industry example for waste products, support for economic opportunities in resource recovery, and bans on the disposal of recyclable wastes. These measures have produced dramatic results in trying to balance resource supply with demand. The materials sectors which are examples of the strategy's success include fibre, used tires, plastics and composting.

  10. Plastic ingestion by fulmars and shearwaters at Sable Island, Nova Scotia, Canada.

    Science.gov (United States)

    Bond, Alexander L; Provencher, Jennifer F; Daoust, Pierre-Yves; Lucas, Zoe N

    2014-10-15

    Plastic pollution is widespread in the marine environment, and plastic ingestion by seabirds is now widely reported for dozens of species. Beached Northern Fulmars, Great Shearwaters, Sooty Shearwaters and Cory's Shearwaters are found on Sable Island, Nova Scotia, Canada regularly, and they can be used to assess plastic pollution. All species except Cory's Shearwaters contained plastic debris in their gastrointestinal tracts. Northern Fulmars, Sooty Shearwaters and Great Shearwaters all showed high prevalence of plastic ingestion (>72%), with Northern Fulmars having the highest number and mass of plastics among the species examined. There was no difference in plastic ingestion between sexes or age classes. In all species user plastics made up the majority of the pieces found, with industrial pellets representing only a small proportion in the samples. Sable Island could be an important monitoring site for plastic pollution in Atlantic Canada. Copyright © 2014 Elsevier Ltd. All rights reserved.

  11. Total mineral material, acidity, sulphur, and nitrogen in rain and snow at Kentville, Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Herman, F A; Gorham, E

    1957-01-01

    Analyses of total ash, sulphur, ph, ammonia, and nitrate nitrogen have been made on 23 monthly precipitation samples and 17 individual snow samples collected between June 1952 and May 1954 at Kentville, Nova Scotia, in a predominantly agricultural area. Mean annual supply of total mineral ash was 95 kg/ha, of sulphur 9.1 hg/ha, of ammonia nitrogen 2.8 kg/ha, and of nitrate nitrogen 1.1 kg/ha. Average pH was 5.7, and rains more acid than this exhibited higher levels of both nitrate and sulphur, and a marked correlation between the latter and ammonia. Snow samples had much lower concentrations of ash, sulphur, and nitrogen than rain samples collected in the same months, which may perhaps indicate a lower efficiency of snow flakes in removing materials from the atmosphere.

  12. Broad band seismology in the Scotia region. The base Esperanza seismological observatory

    International Nuclear Information System (INIS)

    Russi, M.; Costa, G.; Febrer, J.

    1995-08-01

    The lithospheric study and the identification of relevant lateral heterogeneities in the Antarctic continent and borderlands, is essential to understand the geodynamic evolution both of the continental and oceanic bordering regions. The complexity of the geological evolution and the structural properties of the lithosphere in the Scotia area have been stressed by many authors. The present setting of the area is the result of the mutual interaction among the Antarctic, South American and several minor plants whose geodynamic history and actual boundaries are still partially unknown. The intense seismic activity that characterizes the region encourages the use of the seismological approach to investigate the lithospheric structure of the area. Since January 1992 a broad band three components station is operating at the Antarctic base Esperanza in the NE area of Antarctic Peninsula. The station has been installed with financial support of the Italian Programma Nazionale di Ricerche in Antartide (PNRA) by Osservatorio Geofisico Sperimentale (OGS) and Instituto Antartico Argentino (IAA). Russi et al. (1994) have analyzed selected recordings using the frequency-time analysis (FTAN) method obtaining some relevant information on the large scale structure of the lithosphere in the Scotia region even if data recorded by a single station were available. The extension of our analysis to further events and to horizontal component records is here presented. Within the framework of the international co-operation to the Antarctic Seismographic Network, the OGS and the IAA are upgrading the Esperanza station and installing an additional broad band station near the town of Ushuaia (Tierra del Fuego, Argentina) with the financial support of PNRA. The inversion of the dispersion curves through the FTAN of the signals recorded by an increased number of stations and generated by events with source-station paths spanning the region will allow us to extract the elastic and anelastic

  13. Impacts of rising sea temperature on krill increase risks for predators in the Scotia Sea

    Science.gov (United States)

    Hill, Simeon L.; Hinke, Jefferson T.; Phillips, Tony; Watters, George M.

    2018-01-01

    Climate change is a threat to marine ecosystems and the services they provide, and reducing fishing pressure is one option for mitigating the overall consequences for marine biota. We used a minimally realistic ecosystem model to examine how projected effects of ocean warming on the growth of Antarctic krill, Euphausia superba, might affect populations of krill and dependent predators (whales, penguins, seals, and fish) in the Scotia Sea. We also investigated the potential to mitigate depletion risk for predators by curtailing krill fishing at different points in the 21st century. The projected effects of ocean warming on krill biomass were strongest in the northern Scotia Sea, with a ≥40% decline in the mass of individual krill. Projections also suggest a 25% chance that krill biomass will fall below an established depletion threshold (75% of its unimpacted level), with consequent risks for some predator populations, especially penguins. Average penguin abundance declined by up to 30% of its unimpacted level, with up to a 50% chance of falling below the depletion threshold. Simulated krill fishing at currently permitted harvest rates further increased risks for depletion, and stopping fishing offset the increased risks associated with ocean warming in our model to some extent. These results varied by location and species group. Risk reductions at smaller spatial scales also differed from those at the regional level, which suggests that some predator populations may be more vulnerable than others to future changes in krill biomass. However, impacts on predators did not always map directly to those for krill. Our findings indicate the importance of identifying vulnerable marine populations and targeting protection measures at appropriate spatial scales, and the potential for spatially-structured management to avoid aggravating risks associated with rising ocean temperatures. This may help balance tradeoffs among marine ecosystem services in an uncertain future

  14. Nova Scotia offshore to Grand Banks connection : Mesozoic basins on a transform margin

    Energy Technology Data Exchange (ETDEWEB)

    Conway, L.E.; Martin, M.R.; Enachescu, M.E.; Atkinson, I.; Stead, J.E. [Memorial Univ. of Newfoundland, St. John' s, NL (Canada). Dept. of Earth Sciences and Pan-Atlantic Petroleum Systems Consortium

    2005-07-01

    The renewed interest in the southern Grand Banks has resulted in new active exploration licenses, seismic acquisition programs and planned drilling in the South Whale and Laurentian basins. The basins are located northeast of the Scotian margin, about 200 km south of the east coast of Newfoundland, in shallow to intermediate waters in an area free of icebergs. The Scotian and Newfoundland offshore areas are separated by the St. Lawrence Tertiary channel. A provincial boundary divides the jurisdiction over sea resources. The long political moratorium which had been imposed on the Laurentian Basin was resolved during the summer of 2003 with the establishment of the provincial boundary. Some regional geological maps of the East Coast Mesozoic sedimentary area indicate continuity between the Orpheus Graben and northern Scotian Shelf and Slope basins (Nova Scotia) and Laurentian and South Whale basins (Newfoundland). In contrast, other maps represents them as being separated by faults or ridges that affect the basin development and complicate the tectono-structural framework initiated in Late Triassic-Early Jurassic periods. Argo salt features found in seismic sections on both sides of the provincial boundary indicate that Atlantic Canada basins were interconnected during the marine phase of the Thethys rifting stage, most likely up to the time of Scotian Shelf break-up. During the Late Jurassic, marine, oil prone source rocks were deposited in the Grand Banks basins and terrestrial to marine, gas prone source rocks were deposited offshore Nova Scotia. Modern industry 2D data donated by GSI and WesternGeco were used to examine the structural and stratigraphic framework of the basins. Common geological and geomorphologic features were emphasized along with the disparity between the structural element, stratigraphy and quality of petroleum systems of the two basins.

  15. Can households earning minimum wage in Nova Scotia afford a nutritious diet?

    Science.gov (United States)

    Williams, Patricia L; Johnson, Christine P; Kratzmann, Meredith L V; Johnson, C Shanthi Jacob; Anderson, Barbara J; Chenhall, Cathy

    2006-01-01

    To assess the affordability of a nutritious diet for households earning minimum wage in Nova Scotia. Food costing data were collected in 43 randomly selected grocery stores throughout NS in 2002 using the National Nutritious Food Basket (NNFB). To estimate the affordability of a nutritious diet for households earning minimum wage, average monthly costs for essential expenses were subtracted from overall income to see if enough money remained for the cost of the NNFB. This was calculated for three types of household: 1) two parents and two children; 2) lone parent and two children; and 3) single male. Calculations were also made for the proposed 2006 minimum wage increase with expenses adjusted using the Consumer Price Index (CPI). The monthly cost of the NNFB priced in 2002 for the three types of household was 572.90 dollars, 351.68 dollars, and 198.73 dollars, respectively. Put into the context of basic living, these data showed that Nova Scotians relying on minimum wage could not afford to purchase a nutritious diet and meet their basic needs, placing their health at risk. These basic expenses do not include other routine costs, such as personal hygiene products, household and laundry cleaners, and prescriptions and costs associated with physical activity, education or savings for unexpected expenses. People working at minimum wage in Nova Scotia have not had adequate income to meet basic needs, including a nutritious diet. The 2006 increase in minimum wage to 7.15 dollars/hr is inadequate to ensure that Nova Scotians working at minimum wage are able to meet these basic needs. Wage increases and supplements, along with supports for expenses such as childcare and transportation, are indicated to address this public health problem.

  16. Temperature, salinity, oxygen and other measurements collected in the Scotia Sea from 04 August 1997 to 05 September 1997 (NODC Accession 0000753)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature profile and other data were collected using bottle and CTD casts in the Weddell and Scotia Sea from NATHANIEL B. PALMER. Data were collected from 04...

  17. Long-term response in episodic acidification to declining SO42– deposition in two streams in Nova Scotia

    Directory of Open Access Journals (Sweden)

    H. Laudon

    2002-01-01

    Full Text Available Trends in anthropogenically driven episodic acidification associated with extended winter snow melt/rain episodes between 1983 and 1998 were investigated for two streams in Nova Scotia, Canada. The anthropogenic contribution to Acid Neutralization Capacity (ANC was analysed using the Boreal Dilution Model (Bishop et al., 2000 modified by applying a sea-salt correction to all input hydrochemistry. The anthropogenic contribution to episodic ANC decline was statistically significant and strongly correlated with the decline in acid deposition, which decreased by approximately 50% during the period of record. Sensitivity analysis demonstrated that the BDM can be applied to surface waters with sea-salt contributions although the correction increases model uncertainty. Results of this study demonstrate the effectiveness of reduced emissions in North America in the last decades in decreasing the severity of episodic acidification in the Atlantic region of Canada. Keywords: episodic acidification, acidification recovery, Nova Scotia, snowmelt, winter

  18. Integrated Digital Technologies for the Architectural Rehabilitation & Conservation of Beinn Bhreagh Hall & Surrounding Site, Nova Scotia, Canada

    Science.gov (United States)

    Percy, K.; Ward, S.; Santana Quintero, M.; Morrison, T.

    2015-08-01

    This contribution summarizes the collaboration between Carleton Immersive Media Studio (CIMS) and Heritage Standing in the use of digital technologies to document the Beinn Bhreagh Hall historic site (house and immediate surroundings) in Baddeck, Nova Scotia for its rehabilitation and protection. The project objectives were to develop a prototype for research and training using 3D scanning, and Building Information Modelling (BIM), as well as other emerging surveying tools to understand the state of conservation of Historic Places in Canada, providing relevant and appropriate information for their rehabilitation and maintenance. The vehicle of this research was the documentation and modelling of this important landmark, the summer home of Dr. Alexander Graham Bell in Victoria County, Nova Scotia. This unique 19thC building, currently under review for designated as a national historic site.

  19. Restoration ecology: aiding and abetting secondary succession on abandoned peat mines in Nova Scotia and New Brunswick, Canada

    OpenAIRE

    P.J. Vander Kloet; T.S. Avery; S.P. Vander Kloet; G.R. Milton

    2012-01-01

    The efficacy of using vegetative clumps derived from seeds with a variety of origins to establish nuclei for regeneration of bog vegetation on abandoned peat mines in Nova Scotia and New Brunswick (Canada) was tested using seeds within scats (excrement) and seeds from berries, various techniques for creating clumps, and different clump sizes. Direct placement of scat pieces on peat in the field did not produce successful colonisation. Vegetative clumps begun in a greenhouse, whether from seed...

  20. The environmental and socio-economic impacts and benefits associated with developing a natural gas distribution system in Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Buszynski, M.E.; Peacock, T. [Sempra Atlantic Gas Inc., Halifax, NS (Canada)

    2000-07-01

    The discovery of large natural gas reserves off the Scotian Shelf has resulted in the development and construction of offshore production platforms as well as underwater and onshore pipelines to transport natural gas to markets on the eastern seaboard. A billion-dollar expenditure is proposed to establish a local distribution company to construct and maintain approximately 8000 km of distribution and lateral pipelines in the province of Nova Scotia. The many aspects of the proposed program were described with particular focus on the regulatory hearings. The paper also discussed the different landscapes that will be crossed and the specialized construction techniques that will be used to meet environmental and economic challenges. The mechanisms in place to ensure maximum benefit for Nova Scotians were also discussed. The proposed project was also compared to other local megaprojects in the province such as the Sable Offshore Energy Project and the Interprovincial Pipeline through Nova Scotia and New Brunswick. Some of the successful strategies for implementing benefits plans related to large energy projects were also described. Sempra has been awarded the franchise to distribute natural gas in Nova Scotia. The company has developed a benefits plan that offers significant local involvement in terms of labour and materials. 4 figs.

  1. “Not a Vacation, But a Hardening Process”: The Self-Empowerment Work of Therapeutic Craft in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Erin Morton

    2014-10-01

    Full Text Available This article will examine the development of a state-sponsored therapeutic craft regime in Nova Scotia in the early to mid-twentieth century. Built on the notion that postwar residents needed "work therapy - not a vacation, but a hardening process" (Black n.d. a: 3 - therapeutic craft emerged in Nova Scotia through a complex combination of the individualization of work habits, the desire to construct an antimodern regional identity around handwork, and the notion that both infirm patients and the province as a whole could be healed from economic stagnation through craft. Key to the success of Nova Scotia's therapeutic craft regime was occupational therapist Mary E. Black's career as director of the provincial government's Handicrafts and Home Industries Division from 1943 to 1955. Black's healthcare training led her to seek out therapeutic possibilities in everyday work activities, not to mention a therapeutic solution to what she called "the atti-tude of most Nova Scotians"[:] defeatism" (Black 1949: 46. Her ability to turn seemingly disparate things - such as Scandinavian design, the ordered work of occupational rehabilitation, and a phenomenological focus on what she called “in-dividualistic existence” (Black n.d. b: 2 - into a unified therapeutic solution demonstrates that the contemporary rise of therapeutic culture under the increased individualism of the neoliberal era has an established historical root in the postwar period that remains important to understand.

  2. Crustal structure beneath discovery bank in the South Scotia Sea from group velocity tomography and seismic reflection data

    International Nuclear Information System (INIS)

    Vuan, A.; Lodolo, E.; Panza, G.F.

    2003-09-01

    Bruce, Discovery, Herdman and Jane Banks, all located along the central-eastern part of the South Scotia Ridge (i.e., the Antarctica-Scotia plate boundary), represent isolated topographic reliefs surrounded by relatively young oceanic crust, whose petrological and structural nature is still the subject of speculations due to the lack of resolving data. In the Scotia Sea and surrounding regions negative anomalies of about 34% are reported in large-scale group velocity tomography maps. The spatial resolution (∼500 km) of these maps does not warrant any reliable interpretation of such anomalies. A recent surface wave tomography in the same area, performed using broad band seismic stations and 300 regional events, shows that in the period range from 15 s to 50 s the central-eastern part of the South Scotia Ridge is characterized by negative anomalies of the group velocities as large as 6. The resolution of our data set (∼300 km) makes it possible to distinguish an area (centered at 61 deg S and 36 deg W) with a crust thicker than 25 km, and a shear wave velocity vs. depth profile similar to that found beneath the northern tip of the Antarctic Peninsula and southern South America. Rayleigh and Love wave dispersion curves are inverted in the period range from 15 s to 80 s to obtain shear wave velocity profiles that suggest a continental nature of Discovery Bank. The continental-type crust of this topographic relief is in agreement with the interpretation of a multi-channel seismic reflection profile acquired across this rise. Peculiar acoustic facies are observed in this profile and are interpreted as thinned and faulted continental plateau. The boundaries of the negative group velocity anomalies are marked by a high seismicity rate. Historical normal faulting earthquakes with magnitude around 7 are localised between the low velocity anomaly region in the eastern South Scotia Ridge and the high velocity anomaly region associated with the surrounding oceanic crust

  3. Foraging Habitat and Chick Diets of Roseate Tern, Sterna dougallii, Breeding on Country Island, Nova Scotia

    Directory of Open Access Journals (Sweden)

    Jennifer C. Rock

    2007-06-01

    Full Text Available Breeding seabirds are threatened by human activities that affect nesting and foraging habitat. In Canada, one of the seabirds most at risk of extirpation is the Roseate Tern, Sterna dougallii. Although critical nesting habitat has been identified for the Roseate Tern in Canada, its foraging locations and the diet of its chicks are unknown. Therefore, our goal was to determine the foraging locations and diet of chicks of Roseate Tern breeding on Country Island, Nova Scotia, which is one of Canada's two main breeding colonies. In 2003 and 2004, we radio-tracked the Roseate Tern by plane to locate foraging areas and conducted feeding watches to determine the diet of chicks. Roseate Tern foraged approximately 7 km from the breeding colony over shallow water < 5 m deep. In both years, sand lance, Ammodytes spp., was the most common prey item delivered to chicks, followed by hake, Urophycis spp. Our results are consistent with previous work at colonies in the northeastern United States, suggesting that throughout its range, this species may be restricted in both habitat use and prey selection. The reliance on a specific habitat type and narrow range of prey species makes the Roseate Tern generally susceptible to habitat perturbations and reductions in the availability of prey.

  4. Factors which influence Nova Scotia farmers in implementing energy efficiency and renewable energy measures

    International Nuclear Information System (INIS)

    Bailey, J.A.; Gordon, R.; Burton, D.; Yiridoe, E.K.

    2008-01-01

    Improvements in energy efficiency and renewable energy use can reduce farm operating costs and reduce greenhouse gas (GHG) emissions. Responses (n=224, representing a 32% response rate) from a mail survey were used to assess use and interest in energy efficient and renewable energy options on farms in Nova Scotia, Canada. Energy efficiency options used the most were behavior, insulation, and lighting. Few farms used renewable energy options. Approximately 78% of farmers indicated an interest in implementing energy efficiency and renewable energy options. Interest varied by farm type and size. Interest increased with farm size. The two main efficiency options of interest were lighting (60.8%) and insulation (43.7%), while wind power development (55.5%) and solar water heating (24.5%) were the main renewable options of interest. Farmers concerned about power and equipment reliability were less likely to be interested in implementing options. Farmers concerned about the environment were more likely to be interested in implementing options. Current use of certain energy efficiency technologies, such as efficient lighting, influenced implementation interest

  5. Arbitrating a fiction: Canadian federalism and the Nova Scotia/Newfoundland and Labrador boundary dispute

    Energy Technology Data Exchange (ETDEWEB)

    Baier, G. [University of British Columbia, Dept. of Political Science, Vancouver, BC(Canada); Groarke, P.

    2003-09-30

    The dispute between the provinces of Nova Scotia and Newfoundland and Labrador, regarding ownership of natural resources to be found in the offshore area lying between the two provinces is discussed. Constitutionally, ownership of offshore natural resources belongs to the federal government. In this instance, the intention was to share control over development and revenues with the provinces through joint management accords, however, a dispute over offshore boundary arose, which eventually resulted in an arbitration tribunal. This paper analyzes the terms of reference for the tribunal and its findings, and concludes that the tribunal process was flawed. The authors cast doubts on the appropriateness of the tribunal's role, the method by which it reached its decision, and the legality of its findings. They conclude that the tribunal merely cloaks a political decision in legal garb since there are no genuine boundaries between the provinces, and the tribunal process simply apportioned federal resources between two provinces. The authors ultimately conclude that by resorting to the tribunal process the federal minister of natural resources was able to avoid political responsibility for making an unpopular decision by relying on a pseudo-judicial body for technical recommendations, and in so doing undermined the legitimacy of the Canadian federal system by obscuring the already murky lines of accountability of the federal and provincial governments. 57 end notes.

  6. Shaded seafloor relief, backscatter strength, and surficial geology; German Bank, Scotian Shelf, offshore Nova Scotia

    Science.gov (United States)

    Todd, B.J.; Valentine, Page C.

    2010-01-01

    This map is part of a three-map series of German Bank, located on the Scotian Shelf off southern Nova Scotia.  This map is the product of a number of surveys (1997-2003) that used a multibeam sonar system to map 5321 km2 of the seafloor.  Other surveys collected geological data for scientific interpretation.  This map sheet shows the seafloor topography of German Bank in shaded-relief view and seafloor depth (coded by colour) at a scale of 1:1000,000.  Topographic contours generated from the multibeam data are shown (in white) on the colour-coded multibeam topography at a depth interval of 20 m.  Bathymetic contours (in blue) outside the multibeam survey area, presented at a depth interval of 10 m, are from the Natural Resource Map series (Canadian Hydrographic Service, 1967, 1971a, 1971b, 1972). Sheet 2 shows coloured backscatter strength in shaded-relief view.  Sheet 3 shows seafloor topography in shaded-relief view with colour-coded surficial geological units.

  7. Dispersion and toxicity of metals from abandoned gold mine tailings at Goldenville, Nova Scotia, Canada

    International Nuclear Information System (INIS)

    Wong, H.K.T.; Gauthier, A.; Nriagu, J.O.

    1999-01-01

    As its name indicates, Goldenville was a famous gold mining area in Nova Scotia where large quantities of mercury were used in the gold recovery process. It is estimated that the 3 million tons of tailings left from the mining activities which lasted from 1860 to 1945 contain 470 kg of Cd, 37-300 kg of Pb, 6800 kg of Hg, 20-700 kg of As and 2600 kg of Tl. Analysis of metal contents of stream water, stream and lake sediments, tailings, and vegetation show that the tailings have been distributed over time across the stream basin to form a tailing field of approximately 2 km 2 . There is a continuous release of As, Hg, Pb, Tl and other metals from the tailing field, resulting in contamination of ecosystems downstream including the Gagogan Harbor of the Atlantic Ocean. Stream water and sediments of Lake Gagogan located downstream from the mine were found toxic to the benthic community. A loss of fish habitat was observed. Although the mines were closed over 50 years ago, sedimentary records of metal loadings into Lake Gagogan show that the release of metals from the tailings has not slowed down. Analysis of metal tolerant species in the area suggests that horsetails (Equisetum rubiaceae and E. sylvaticum) can be used in phytoremediation of sites contaminated with arsenic and mercury. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

  8. The energy accounts for the Nova Scotia genuine progress index : executive summary

    International Nuclear Information System (INIS)

    Lipp, J.; Cain, S.; Colman, R.; Parmenter, R.; Milne, K.; Mullaly, H.; Wysocki, A.

    2005-10-01

    GPI Atlantic has developed a Genuine Progress Index (GPI) involving a new measure of sustainability, wellbeing and quality of life in order to better evaluate energy supply and demand by accounting for all benefits and costs including natural capital, social capital, human capital, and conventional produced capital. The executive summary provides an energy overview and presents indicators of energy sustainability including socio-economic, health and environmental and institutional indicators. Socio-economic indicators are organized across the following 6 areas of concern: reliability, affordability, employment; energy efficiency, energy consumption; and energy production and supply. Health and environmental trends examined include carbon monoxide; nitrogen oxide; sulphur dioxide; mercury; total particulate matter; volatile organic compounds; and greenhouse gas emissions. Trends over time are assessed to determine if energy use is becoming more or less sustainable. Institutional indicators are grouped according to several areas of concern, such as leading by example; creating societal change; reporting; and evaluation. The full cost of energy was then discussed using the underlying physical indicators. It was concluded that Nova Scotia is not making sufficient progress towards sustainability in its energy system, and that the production and use of energy are the leading causes of a number of serious environmental problems. Several recommendations are made for government to lead on a number of initiatives. 4 tabs

  9. Recovery following experimental harvesting of Laminaria longicruris and L. digitata in southwestern Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Smith, B D

    1985-01-01

    Laminaria population variables and understory community composition were monitored just prior to, and for two summers following, a September 1980 experimental total harvest of L. longicruris De la Pylaie and L. digitata (L.) Lamouroux within two plots in Lobster Bay, Nova Scotia. Both plots, distinguished mainly by depth, were characterized by high Laminaria standing crop and no recent history of extensive sea urchin grazing. Within the shallower plot (2-3 m below MSL), recovery could not be assessed thoroughly due to ice damage, but within the deeper plot (3-4 m below MSL), L. longicruris regrew cropped biomass and attained maximum observed abundance within one year. Both Laminaria species required two years to mature to pre-harvest population characteristics. Survivorship of 0-1 year old and mature populations of both species was generally low (0-67% per year); however, the higher maximum life expectancy of L. digitata (>4 years vs 2 years) can result in that species persisting to the disadvantage of L. longicruris. Analysis of understory community composition for both harvested plots and their adjacent controls weakly distinguished the harvested plots one summer after harvesting from all others. It is doubtful the distinction is attributable to harvesting and in neither site was there evidence of a critical change in the understory community. Management implications for the commercial harvest of the brown alga Laminaria are discussed.

  10. Dispersion and toxicity of metals from abandoned gold mine tailings at Goldenville, Nova Scotia, Canada

    Energy Technology Data Exchange (ETDEWEB)

    Wong, H.K.T. [National Water Research Institute, P.O. Box 5050, Burlington (Canada); Gauthier, A. [Environmental Protection Branch, Environment Canada, Dartmouth, Nova Scotia (Canada); Nriagu, J.O. [Department of Environmental and Industrial Health, School of Public Health, University of Michigan, Ann Arbor, MI (United States)

    1999-03-22

    As its name indicates, Goldenville was a famous gold mining area in Nova Scotia where large quantities of mercury were used in the gold recovery process. It is estimated that the 3 million tons of tailings left from the mining activities which lasted from 1860 to 1945 contain 470 kg of Cd, 37-300 kg of Pb, 6800 kg of Hg, 20-700 kg of As and 2600 kg of Tl. Analysis of metal contents of stream water, stream and lake sediments, tailings, and vegetation show that the tailings have been distributed over time across the stream basin to form a tailing field of approximately 2 km{sup 2}. There is a continuous release of As, Hg, Pb, Tl and other metals from the tailing field, resulting in contamination of ecosystems downstream including the Gagogan Harbor of the Atlantic Ocean. Stream water and sediments of Lake Gagogan located downstream from the mine were found toxic to the benthic community. A loss of fish habitat was observed. Although the mines were closed over 50 years ago, sedimentary records of metal loadings into Lake Gagogan show that the release of metals from the tailings has not slowed down. Analysis of metal tolerant species in the area suggests that horsetails (Equisetum rubiaceae and E. sylvaticum) can be used in phytoremediation of sites contaminated with arsenic and mercury. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

  11. Moving Forward with School Nutrition Policies: A Case Study of Policy Adherence in Nova Scotia.

    Science.gov (United States)

    McIsaac, Jessie-Lee D; Shearer, Cindy L; Veugelers, Paul J; Kirk, Sara F L

    2015-12-01

    Many Canadian school jurisdictions have developed nutrition policies to promote health and improve the nutritional status of children, but research is needed to clarify adherence, guide practice-related decisions, and move policy action forward. The purpose of this research was to evaluate policy adherence with a review of online lunch menus of elementary schools in Nova Scotia (NS) while also providing transferable evidence for other jurisdictions. School menus in NS were scanned and a list of commonly offered items were categorized, according to minimum, moderate, or maximum nutrition categories in the NS policy. The results of the menu review showed variability in policy adherence that depended on food preparation practices by schools. Although further research is needed to clarify preparation practices, the previously reported challenges of healthy food preparations (e.g., cost, social norms) suggest that many schools in NS are likely not able to use these healthy preparations, signifying potential noncompliance to the policy. Leadership and partnerships are needed among researchers, policy makers, and nutrition practitioners to address the complexity of issues related to food marketing and social norms that influence school food environments to inspire a culture where healthy and nutritious food is available and accessible to children.

  12. New Professionals on tap? The human resource challenges in developing a new generation of municipal and local government managers in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Andrew Molloy

    2010-03-01

    Full Text Available Canadian governments are facing significant human resource management challenges due to pending retirements, projected labour market shortages and the workplace expectations of New Professionals. This paper explores human resource recruitment planning initiatives, which have been undertaken by Nova Scotia municipalities, in order to attract and retain a new generation of municipal government managers. We will argue, in line with a recent Association of Municipal Administrators (AMA of Nova Scotia municipal report that Nova Scotia municipalities must take intergenerational issues into account, for management succession planning to be successful. Our exploration of municipal succession planning will take place in the context of a larger study, which we have done on “New Professional” recruitment, retention and development initiatives in Canada

  13. SU-E-I-33: Establishment of CT Diagnostic Reference Levels in Province Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Tonkopi, E; Abdolell, M; Duffy, S [Dalhousie University and Queen Elizabeth II Health Sciences Centre, Halifax, NS (Canada)

    2015-06-15

    Purpose: To evaluate patient radiation dose from the most frequently performed CT examinations and to establish provincial diagnostic reference levels (DRLs) as a tool for protocol optimization. Methods: The study investigated the following CT examinations: head, chest, abdomen/pelvis, and chest/abdomen/pelvis (CAP). Dose data, volume CT dose index (CTDIvol) and dose-length product (DLP), were collected from 15 CT scanners installed during 2004–2014 in 11 hospital sites of Nova Scotia. All scanners had dose modulation options and multislice capability (16–128 detector rows). The sample for each protocol included 15 average size patients (70±20 kg). Provincial DRLs were calculated as the 75th percentile of patient dose distributions. The differences in dose between hospitals were evaluated with a single factor ANOVA statistical test. Generalized linear modeling was used to determine the factors associated with higher radiation dose. A sample of 36 abdominal studies performed on three different scanners was blinded and randomized for an assessment by an experienced radiologist who graded the imaging quality of anatomic structures. Results: Data for 900 patients were collected. The DRLs were proposed using CTDIvol (mGy) and DLP (mGy*cm) values for CT head (67 and 1049, respectively), chest (12 and 393), abdomen/pelvis (16 and 717), and CAP (14 and 1034). These DRLs were lower than the published national data except for the head CTDIvol. The differences between the means of the dose distributions from each scanner were statistically significant (p<0.05) for all examinations. A very weak correlation was found between the dose and the scanner age or the number of slices with Pearson’s correlation coefficients of 0.011–0.315. The blinded analysis of image quality demonstrated no clinically significant difference except for the noise category. Conclusion: Provincial DRLs were established for typical CT examinations. The variations in dose between the hospitals

  14. Suicidal behaviours in adolescents in Nova Scotia, Canada: protective associations with measures of social capital.

    Science.gov (United States)

    Langille, Donald B; Asbridge, Mark; Kisely, Steve; Rasic, Daniel

    2012-10-01

    Few studies of adolescent suicidality have examined its associations with social capital. We explored associations of measures of individual level social capital with self-reported suicide ideation and suicide attempt in adolescents in Cape Breton, Nova Scotia, Canada, controlling for other factors known to be associated with adolescent suicidality. We surveyed 1,597 grade 10-12 students at three high schools in 2006 using self-completion questionnaires. Both sexes were combined for analysis. Outcome measures were suicidal ideation and attempt in the previous year. Measures of social capital included perceptions of trustworthiness and helpfulness of others at school, frequency of religious attendance and participation in extracurricular activities. Logistic regressions were carried out to determine associations of social capital with suicidality while controlling for other factors. Perceived trustworthiness and helpfulness were protective for suicidal ideation and suicide attempt in the previous year. In adjusted analyses, there were interactions of gender and social capital-females reporting more social capital were more protected from suicide attempt relative to males with similar levels of social capital. This study provides initial evidence of protective associations of individual level social capital with adolescent suicidality. Our findings suggest that among adolescents low social capital as measured by perceptions of trust and helpfulness of others at school may be a warning sign for suicidality, particularly for females. It may be helpful to inquire of young people how they perceive the trustworthiness and helpfulness of their school environment as a measure of how supportive that environment might be to them when they are facing challenges to their mental health.

  15. U-Pb and Rb-Sr geochronology of the Wedgeport granitoid pluton, southwestern Nova Scotia

    International Nuclear Information System (INIS)

    Cormier, R.F.; Keppie, J.D.; Odom, A.L.

    1988-01-01

    Zircons from biotite monzogranite of the Wedgeport Pluton, intrusive into deformed metasediments of the Cambrian(?) Goldenville formation in the southwestern Meguma Terrane of Nova Scotia, yield concordant U-Pb ages of 316 ± 5 Ma. This is interpreted as the time of intrusion and crystallization. Within the error limits, the 323 ± 0.0056 Rb-Sr analyses of mineral separates of biotite, potassium feldspar, and quartz-plagioclase from several samples yield subparallel, internal isochrons with an average age of 257 ± 8 Ma. Initial ratios of the internal isochrons range from 0.716 to 0.759. A slow-cooling model for the latter data is discarded because the mineral data fall on straight lines. Instead, a reheating event related to plutonism ca 257 Ma ago, which was sufficient to cause local grain-to-grain migration and reequilibration of strontium and rubidium but not large-scale redistribution, is invoked. This reheating is also inferred to be responsible for the hydrothermal alteration and Sn-U mineralization concentrated along the northwestern margin of the pluton. A dextral northeast-southeast shear zone cutting the pluton is also inferred to be ca. 257 Ma old. It may be related to the last stages of westward abduction of the Meguma Terrane. These results provide a clear example of Permo-Carboniferous plutonism in the southwestern Meguma Terrane and suggest a similar interpretation may apply to other anomalously young ages recorded in this area. In light of these results, the Permo-Carboniferous age of the large East Kemptville tin deposit and its location in a dextral shear zone suggest that the association of younger plutonism and shear zones may be a significant factor for economic mineralization. (22 refs., 4 tabs., 3 figs.)

  16. Chemical characteristics of North American surface layer outflow: Insights from Chebogue Point, Nova Scotia

    Science.gov (United States)

    Millet, Dylan B.; Goldstein, Allen H.; Holzinger, Rupert; Williams, Brent J.; Allan, James D.; Jimenez, José L.; Worsnop, Douglas R.; Roberts, James M.; White, Allen B.; Hudman, Rynda C.; Bertschi, Isaac T.; Stohl, Andreas

    2006-12-01

    We present a factor analysis-based method for differentiating air masses on the basis of source influence and apply the method to a broad suite of trace gas and aerosol measurements collected at Chebogue Point, Nova Scotia, during the summer of 2004 to characterize the chemical composition of atmospheric outflow from eastern North America. CO, ozone, and aerosol mass were elevated by 30%, 56%, and more than 300% at Chebogue Point during U.S. outflow periods. Organic aerosol mass was highest during U.S. pollution events, but made up the largest fraction (70%) of the total aerosol during periods of primary and especially secondary biogenic influence, indicating the importance of both anthropogenic and biogenic organic aerosol. Anthropogenic and oxygenated volatile organic compounds account for the bulk of the gas-phase organic carbon under most conditions; however, biogenic compounds are important in terms of chemical reactivity. Biogenic emissions thus have a significant impact on the chemistry of air masses downwind of the polluted northeastern United States. Using output from a global 3-D model of atmospheric composition (GEOS-Chem), we estimate that CO directly emitted from U.S. pollution sources makes up 28% of the total CO observed at Chebogue Point during U.S. outflow events and 19% at other times, although more work is needed to improve U.S. emission estimates for CO and other pollutants. We conclude that the effects of North American pollution on the chemistry of the western North Atlantic boundary layer are pervasive and not restricted to particular events.

  17. Circulation, retention, and mixing of waters within the Weddell-Scotia Confluence, Southern Ocean: The role of stratified Taylor columns

    Science.gov (United States)

    Meredith, Michael P.; Meijers, Andrew S.; Naveira Garabato, Alberto C.; Brown, Peter J.; Venables, Hugh J.; Abrahamsen, E. Povl; Jullion, Loïc.; Messias, Marie-José

    2015-01-01

    The waters of the Weddell-Scotia Confluence (WSC) lie above the rugged topography of the South Scotia Ridge in the Southern Ocean. Meridional exchanges across the WSC transfer water and tracers between the Antarctic Circumpolar Current (ACC) to the north and the subpolar Weddell Gyre to the south. Here, we examine the role of topographic interactions in mediating these exchanges, and in modifying the waters transferred. A case study is presented using data from a free-drifting, intermediate-depth float, which circulated anticyclonically over Discovery Bank on the South Scotia Ridge for close to 4 years. Dimensional analysis indicates that the local conditions are conducive to the formation of Taylor columns. Contemporaneous ship-derived transient tracer data enable estimation of the rate of isopycnal mixing associated with this column, with values of O(1000 m2/s) obtained. Although necessarily coarse, this is of the same order as the rate of isopycnal mixing induced by transient mesoscale eddies within the ACC. A picture emerges of the Taylor column acting as a slow, steady blender, retaining the waters in the vicinity of the WSC for lengthy periods during which they can be subject to significant modification. A full regional float data set, bathymetric data, and a Southern Ocean state estimate are used to identify other potential sites for Taylor column formation. We find that they are likely to be sufficiently widespread to exert a significant influence on water mass modification and meridional fluxes across the southern edge of the ACC in this sector of the Southern Ocean.

  18. Mapping wetlands in Nova Scotia with multi-beam RADARSAT-2 Polarimetric SAR, optical satellite imagery, and Lidar data

    Science.gov (United States)

    Jahncke, Raymond; Leblon, Brigitte; Bush, Peter; LaRocque, Armand

    2018-06-01

    Wetland maps currently in use by the Province of Nova Scotia, namely the Department of Natural Resources (DNR) wetland inventory map and the swamp wetland classes of the DNR forest map, need to be updated. In this study, wetlands were mapped in an area southwest of Halifax, Nova Scotia by classifying a combination of multi-date and multi-beam RADARSAT-2 C-band polarimetric SAR (polSAR) images with spring Lidar, and fall QuickBird optical data using the Random Forests (RF) classifier. The resulting map has five wetland classes (open-water/marsh complex, open bog, open fen, shrub/treed fen/bog, swamp), plus lakes and various upland classes. Its accuracy was assessed using data from 156 GPS wetland sites collected in 2012 and compared to the one obtained with the current wetland map of Nova Scotia. The best overall classification was obtained using a combination of Lidar, RADARSAT-2 HH, HV, VH, VV intensity with polarimetric variables, and QuickBird multispectral (89.2%). The classified image was compared to GPS validation sites to assess the mapping accuracy of the wetlands. It was first done considering a group consisting of all wetland classes including lakes. This showed that only 69.9% of the wetland sites were correctly identified when only the QuickBird classified image was used in the classification. With the addition of variables derived from lidar, the number of correctly identified wetlands increased to 88.5%. The accuracy remained the same with the addition of RADARSAT-2 (88.5%). When we tested the accuracy for identifying wetland classes (e.g. marsh complex vs. open bog) instead of grouped wetlands, the resulting wetland map performed best with either QuickBird and Lidar, or QuickBird, Lidar, and RADARSAT-2 (66%). The Province of Nova Scotia's current wetland inventory and its associated wetland classes (aerial-photo interpreted) were also assessed against the GPS wetland sites. This provincial inventory correctly identified 62.2% of the grouped wetlands

  19. Thoughts on controls on evolution and dispersal of benthos in the Magellan-Scotia Sea region: a workshop proposal

    Directory of Open Access Journals (Sweden)

    Michael R.A. Thomson

    2005-12-01

    Full Text Available The Scotia Arc and the Scotia Sea comprise a geologically young feature of the Earth’s surface that evolved over the last 40 million years (Ma or so, between the southern tip of South America and the northern tip of the Antarctic Peninsula. With the notable exception of the much younger South Sandwich Islands, the islands, banks and seamounts of the arc represent dispersed fragments of a previous continental link between southern South America (Magellan region and the Antarctic Peninsula. The benthic marine shelf faunas of the region are the focus of the IBMANT (Investigación Biolólogica Marina en Magallanes relacionada con la Antártida programme, and those of the surrounding oceanic deeps are the focus of ANDEEP (Antarctic Benthic Deep-Sea Biodiversity. Elucidating the potential relationships between the faunas of the region and the profound geographical, oceanographic and climatic changes undergone by the region in later Cenozoic time is hampered by significant unknowns in the geological history, the expense of further geoscientific exploration to fill these, and a general lack of communication between the biological and geological science communities. It is suggested that the time is opportune for a truly multidisciplinary workshop at which all the involved science communities have much to gain from the others.

  20. An integrated approach to dam safety evaluation. A case study: Upper Lake Falls Dam, Nova Scotia, Canada

    International Nuclear Information System (INIS)

    Pelletier, P.M.; Rattue, D.A.; Brown, E.R.

    1990-01-01

    Upper Lake Falls Dam is located in southwestern Nova Scotia. It is the uppermost hydroelectric development in a series of six developments on the Mersey River. The total capacity of the Mersey River system is 42 MW. The reservoir of Upper Lake Falls, Lake Rossignol, is the largest in Nova Scotia with a total area of 66 square miles and a gross storage of 800,000 acre-feet. An overview is presented of the hydrologic and hydraulic investigations carried out for the dam, which is classified as having high hazard potential because of permanent village and urban developments located downstream. The general methodology adopted in the study consisted of the following: gathering and verifying all meteorologic and hydrologic data; evaluating the Probable Maximum Precipitation (PMP) assumed to occur over the basin, and of the antecedent conditions prior to the PMP; calibrating a watershed model on flood events generated by rainfall, and by a combination of snowmelt and rainfall, and verifying the model using additional hydrologic events; deriving the Probable Maximum Flood (PMF) using the PMP results simulated on the calibrated watershed model; hydrodynamic routing of the flood hydrograph through all the developments; dambreak analysis, following sequential or independent failures; and flood inundation mapping. Details are given of safety analysis of the earthfill and concrete dam structures, reservoir management and cost-benefit analyses. 7 refs., 8 figs., 1 tab

  1. The economic impact of a partnership-measurement model of disease management: Improving Cardiovascular Outcomes in Nova Scotia (ICONS).

    Science.gov (United States)

    Crémieux, Pierre-Yves; Fortin, Pierre; Meilleur, Marie-Claude; Montague, Terrence; Royer, Jimmy

    2007-01-01

    Improving Cardiovascular Outcomes in Nova Scotia (ICONS) was a five-year, community partnership-based disease-management project that sought, as a primary goal, to improve the care and outcomes of patients with heart disease in Nova Scotia. This program, based on a broad stakeholder partnership, provided repeated measurement and feedback on practices and outcomes as well as widespread communication and education among all partners. From a clinical viewpoint, ICONS was successful. For example, use of proven therapies for the target diseases improved and re-hospitalization rates decreased. Stakeholders also perceived a sense of satisfaction because of their involvement in the partnership. However, the universe of health stakeholders is large, and not many have had an experience similar to ICONS. These other health stakeholders, such as decision-makers concerned with the cost of care and determining the value for cost, might, nonetheless, benefit from knowledge of the ICONS concepts and results, particularly economic analyses, as they determine future health policy. Using budgetary data on actual dollars spent and a robust input-output methodology, we assessed the economic impact of ICONS, including trickle-down effects on the Canadian and Nova Scotian economies. The analysis revealed that the $6.22 million invested in Nova Scotia by the private sector donor generated an initial net increase in total Canadian wealth of $5.32 million and a global net increase in total Canadian wealth of $10.23 million, including $2.27 million returned to the different governments through direct and indirect taxes. Thus, the local, provincial and federal governments are important beneficiaries of health project investments such as ICONS. The various government levels benefit from the direct influx of private funds into the publicly funded healthcare sector, from direct and indirect tax revenues and from an increase in knowledge-related employment. This, of course, is in addition to the

  2. Restoration ecology: aiding and abetting secondary succession on abandoned peat mines in Nova Scotia and New Brunswick, Canada

    Directory of Open Access Journals (Sweden)

    P.J. Vander Kloet

    2012-11-01

    Full Text Available The efficacy of using vegetative clumps derived from seeds with a variety of origins to establish nuclei for regeneration of bog vegetation on abandoned peat mines in Nova Scotia and New Brunswick (Canada was tested using seeds within scats (excrement and seeds from berries, various techniques for creating clumps, and different clump sizes. Direct placement of scat pieces on peat in the field did not produce successful colonisation. Vegetative clumps begun in a greenhouse, whether from seeds extracted from scats or berries, were 60–100 % successful when transplanted into abandoned peat mines depending on the initial size of the transplant. Based on annual growth rate, Vaccinium oxycoccos has the greatest capacity to quickly colonise abandoned peat mines. Other promising taxa were Vaccinium vitis-ideae and the genus Empetrum.

  3. Deadly occupations: Assessing tuberculosis and accidental mortality among male workers in Sydney and Glace Bay, Nova Scotia, 1909–1917

    Directory of Open Access Journals (Sweden)

    Natalie C. Ludlow

    2013-02-01

    Full Text Available This study examines associations between occupation and cause of death among 802 working-age males (15 to 64 years of age who diedin two single-industry communities (Glace Bay and Sydney in Nova Scotia between 1909 and 1917. Employment in mining and steelmanufacturing is assessed for cause-specific mortality among men who died in Canada’s early industrial era, with a particular focus ondeaths due to tuberculosis (n=140, or 18% of deaths and accidents (n=225, or 28% of deaths. Factoring in the effects of occupation,age at death, birthplace, community, and marital status, logistic regression results indicate that, among the men who died, occupation is a significant predictor for accidental deaths (relative to all other causes of death but not for tuberculosis-related deaths. Interpretation of these results is grounded in a broader perspective on the nature of living and working conditions in these two single-industry communities.

  4. Discrepancies between knowledge and practice of childhood motor vehicle occupant safety in Nova Scotia--a population-based study.

    Science.gov (United States)

    Yanchar, Natalie L; Kirkland, Susan A; LeBlanc, John C; Langille, Donald B

    2012-03-01

    To determine discrepancies between knowledge and practice of childhood motor vehicle restraints (CMVRs) and vehicle seating position amongst parents within the province of Nova Scotia. Random telephone survey. The Canadian province of Nova Scotia. Four hundred and twenty-six households with at least one child under the age of 12 years, totaling 723 children. The proportion of parents whose children who should be in a specific stage of CMVR and sitting in the rear seat of the vehicle, and who demonstrate correct knowledge of that restraint system and seating position, yet do not use that restraint system/seating position for their child (demonstrate practice discrepant from their knowledge). Awareness of what restraint system to use is good (>80%). However, knowledge of when it is safe to graduate to the next stage is low (30-55%), most marked for when to use a seatbelt alone. Awareness of the importance of sitting in the rear seat of a vehicle was universal. Discrepancies between knowledge and practice were most marked with booster seats and rear-seating of older children. Factors influencing incorrect practice (prematurely graduated to a higher-level restraint system than what is appropriate for age and weight) included lower household income, caregiver education level, and knowledge of when to graduate from forward-facing car seats and booster seats. Incorrect practice was also more commonly observed amongst children of weight and/or age approaching (but not yet reaching) recommended graduation parameters of the appropriate CMVR. Discrepancies between knowledge and practice are evident through all stages of CMVRs, but most marked with booster seats. The roles of lower socioeconomic status and gaps in CMVR legislation, in influencing discrepant practice, must be acknowledged and suggest the need for targeted education concurrent with development of comprehensive all-stages CMVR policies. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. Development of local knowledge of environmental contamination in Sydney, Nova Scotia: Environmental health practice from an environmental justice perspective

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, Timothy W. [Department of Community Health Sciences, University of Calgary, Calgary, Alberta (Canada); Guyn, Lindsay [Department of Information and Evaluation Unit, Mental Health and Psychiatric Services, Calgary Health Region (Canada); Lane, Stephanie E.

    2006-09-15

    In Sydney, Nova Scotia, from 1901 through 1988 a coke and steel factory operated with no pollution controls, depositing over a million tons of particulate matter and releasing several thousands of tons of coal tar into the estuary. Previously we documented the presence of lead, arsenic and PAHs, in soil above Canadian guidelines, and in house dust in the communities surrounding the site [Lambert, TW, Lane, S. Lead, arsenic, and polycyclic aromatic hydrocarbons in soil and house dust in the communities surrounding the Sydney, Nova Scotia, tar ponds. Environ Health Perspect 2004; 112:35-41.]. In this paper we further the research by documenting and developing community knowledge with a study of resident's observations and experiences of the industrial contamination. We conducted two surveys, a quantitative door-to-door survey and qualitative dust interview, designed to complement each other and bring together the observations and experiences in the different communities to develop the local knowledge. The combined methodology uses techniques from both social and physical science, and was developed with the cooperation of community members. The research supports the proposition that local knowledge adds contextual meaning that complements the physical measurement of environmental contaminants, in order to understand the complex environment in which people live, and the multiple exposure pathways through which they can be affected. Residents in all three communities provided vivid observations and detailed experiences of the industrial pollution in their community and homes. The local knowledge is consistent with our physical data and review of the historical scientific research in Sydney, and supports the inference that the community was adversely impacted by the coke and steel facility. From a justice perspective, the three communities should be equally considered for remediation as part of the 'tar pond remediation policy' rather than the current

  6. Terrestrial liming to promote Atlantic Salmon recovery in Nova Scotia - approaches needed and knowledge gained after a trial application

    Science.gov (United States)

    Sterling, S. M.; Angelidis, C.; Armstrong, M.; Biagi, K. M.; Clair, T. A.; Jackson, N.; Breen, A.

    2014-09-01

    Populations of Atlantic salmon (Salmo salar) in Southwest Nova Scotia (SWNS) have plummeted since the 1980s. Acidification is considered a main threat to this population. The lakes and streams of SWNS were among the most heavily acidified in North America during the last century and calcium levels are predicted to continue to fall in coming decades. One of the most promising mitigation options to reduce the risk of extirpation of the SWNS Salmo salar is terrestrial liming; however, both the chemistry of SWNS rivers, and effective strategies for terrestrial liming in SWNS are poorly understood. Here we have launched the first terrestrial liming study in Nova Scotia, employing a test hydrologic source area liming strategy in a 5 ha experimental catchment in SWNS, Maria Brook; we apply an average local application rate of 13 t ha-1 to 10% of the 47 ha catchment. We employ high frequency stream monitoring to complement grab sampling to identify which constituents pose a threat to Salmo salar and to identify strategies for larger scale terrestrial liming that would fit the local conditions. Results indicate that the water chemistry conditions are currently at toxic levels for Salmo salar throughout the year, with levels of ionic aluminium exceeding toxic thresholds almost 100% of the time. The stream chemistry in Maria Brook is remarkably similar to pre-recovery conditions in other heavily acidified watersheds, such as Birkenes in Norway. Our results support the hypothesis that there has been no recovery from acidification in SWNS. Results from the first year of post-liming do not show an improvement in stream chemistry levels, and further lime application is needed to improve the water chemistry conditions to needed levels for the recovery of Salmo salar.

  7. Incidence and Carrier Frequency of CFTR Gene Mutations in Pregnancies With Echogenic Bowel in Nova Scotia and Prince Edward Island.

    Science.gov (United States)

    Miller, Michelle E; Allen, Victoria M; Brock, Jo-Ann K

    2018-03-01

    Fetal echogenic bowel (echogenic bowel) is associated with cystic fibrosis (CF), with a reported incidence ranging from 1% to 13%. Prenatal testing for CF in the setting of echogenic bowel can be done by screening parental or fetal samples for pathogenic CFTR variants. If only one pathogenic variant is identified, sequencing of the CFTR gene can be undertaken, to identify a second pathogenic variant not covered in the standard screening panel. Full gene sequencing, however, also introduces the potential to identify variants of uncertain significance (VUSs) that can create counselling challenges and cause parental anxiety. To provide accurate counselling for families in the study population, the incidence of CF associated with echogenic bowel and the carrier frequency of CFTR variants were investigated. All pregnancies for which CF testing was undertaken for the indication of echogenic bowel (from Nova Scotia and Prince Edward Island) were identified (January 2007-July 2017). The CFTR screening and sequencing results were reviewed, and fetal outcomes related to CF were assessed. A total of 463 pregnancies with echogenic bowel were tested. Four were confirmed to be affected with CF, giving an incidence of 0.9% in this cohort. The carrier frequency of CF among all parents in the cohort was 5.0% (1 in 20); however, when excluding parents of affected fetuses, the carrier frequency for the population was estimated at 4.1% (1 in 25). CFTR gene sequencing identified an additional VUS in two samples. The incidence of CF in pregnancies with echogenic bowel in Nova Scotia and Prince Edward Island is 0.9%, with an estimated population carrier frequency of 4.1%. These results provide the basis for improved counselling to assess the risk of CF in the pregnancy, after parental carrier screening, using Bayesian probability. Counselling regarding VUSs should be undertaken before gene sequencing. Copyright © 2017 Society of Obstetricians and Gynaecologists of Canada. Published by

  8. Development of local knowledge of environmental contamination in Sydney, Nova Scotia: Environmental health practice from an environmental justice perspective

    International Nuclear Information System (INIS)

    Lambert, Timothy W.; Guyn, Lindsay; Lane, Stephanie E.

    2006-01-01

    In Sydney, Nova Scotia, from 1901 through 1988 a coke and steel factory operated with no pollution controls, depositing over a million tons of particulate matter and releasing several thousands of tons of coal tar into the estuary. Previously we documented the presence of lead, arsenic and PAHs, in soil above Canadian guidelines, and in house dust in the communities surrounding the site [Lambert, TW, Lane, S. Lead, arsenic, and polycyclic aromatic hydrocarbons in soil and house dust in the communities surrounding the Sydney, Nova Scotia, tar ponds. Environ Health Perspect 2004; 112:35-41.]. In this paper we further the research by documenting and developing community knowledge with a study of resident's observations and experiences of the industrial contamination. We conducted two surveys, a quantitative door-to-door survey and qualitative dust interview, designed to complement each other and bring together the observations and experiences in the different communities to develop the local knowledge. The combined methodology uses techniques from both social and physical science, and was developed with the cooperation of community members. The research supports the proposition that local knowledge adds contextual meaning that complements the physical measurement of environmental contaminants, in order to understand the complex environment in which people live, and the multiple exposure pathways through which they can be affected. Residents in all three communities provided vivid observations and detailed experiences of the industrial pollution in their community and homes. The local knowledge is consistent with our physical data and review of the historical scientific research in Sydney, and supports the inference that the community was adversely impacted by the coke and steel facility. From a justice perspective, the three communities should be equally considered for remediation as part of the 'tar pond remediation policy' rather than the current policy of including

  9. The ESASSI-08 cruise in the South Scotia Ridge region: An inverse model property-transport analysis over the Ridge

    Science.gov (United States)

    Palmer, Margarita; Gomis, Damià; Del Mar Flexas, Maria; Jordà, Gabriel; Naveira-Garabato, Alberto; Jullion, Loic; Tsubouchi, Takamasa

    2010-05-01

    The ESASSI-08 oceanographic cruise carried out in January 2008 was the most significant milestone of the ESASSI project. ESASSI is the Spanish component of the Synoptic Antarctic Shelf-Slope Interactions (SASSI) study, one of the core projects of the International Polar Year. Hydrographical and biochemical (oxygen, CFCs, nutrients, chlorophyll content, alkalinity, pH, DOC) data were obtained along 11 sections in the South Scotia Ridge (SSR) region, between Elephant and South Orkney Islands. One of the aims of the ESASSI project is to determine the northward outflow of cold and ventilated waters from the Weddell Sea into the Scotia Sea. For that purpose, the accurate estimation of mass, heat, salt, and oxygen transport over the Ridge is requested. An initial analysis of transports across the different sections was first obtained from CTD and ADCP data. The following step has been the application of an inverse method, in order to obtain a better estimation of the net flow for the different water masses present in the region. The set of property-conservation equations considered by the inverse model includes mass, heat and salinity fluxes. The "box" is delimited by the sections along the northern flank of the SSR, between Elephant Island and 50°W, the southern flank of the Ridge, between 51.5°W and 50°W, the 50°W meridian and a diagonal line between Elephant Island and 51.5°W, 61.75°S. Results show that the initial calculations of transports suffered of a significant volume imbalance, due to the inherent errors of ship-ADCP data, the complicated topography and the presence of strong tidal currents in some sections. We present the post-inversion property transports across the rim of the box (and their error bars) for the different water masses.

  10. Linkage of the Canadian Study of Health and Aging to provincial administrative health care databases in Nova Scotia.

    Science.gov (United States)

    Yip, A M; Kephart, G; Rockwood, K

    2001-01-01

    The Canadian Study of Health and Aging (CSHA) was a cohort study that included 528 Nova Scotian community-dwelling participants. Linkage of CSHA and provincial Medical Services Insurance (MSI) data enabled examination of health care utilization in this subsample. This article discusses methodological and ethical issues of database linkage and explores variation in the use of health services by demographic variables and health status. Utilization over 24 months following baseline was extracted from MSI's physician claims, hospital discharge abstracts, and Pharmacare claims databases. Twenty-nine subjects refused consent for access to their MSI file; health card numbers for three others could not be retrieved. A significant difference in healthcare use by age and self-rated health was revealed. Linkage of population-based data with provincial administrative health care databases has the potential to guide health care planning and resource allocation. This process must include steps to ensure protection of confidentiality. Standard practices for linkage consent and routine follow-up should be adopted. The Canadian Study of Health and Aging (CSHA) began in 1991-92 to explore dementia, frailty, and adverse health outcomes (Canadian Study of Health and Aging Working Group, 1994). The original CSHA proposal included linkage to provincial administrative health care databases by the individual CSHA study centers to enhance information on health care utilization and outcomes of study participants. In Nova Scotia, the Medical Services Insurance (MSI) administration, which drew the sampling frame for the original CSHA, did not retain the list of corresponding health card numbers. Furthermore, consent for this access was not asked of participants at the time of the first interview. The objectives of this study reported here were to examine the feasibility and ethical considerations of linking data from the CSHA to MSI utilization data, and to explore variation in health

  11. Physical and chemical data collected using bottle casts from the GENERAL SAN MARTIN in the Scotia Sea and Weddell Sea from 14 December 1963 to 11 January 1964 (NODC Accession 0000791)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Physical and chemical data were collected using bottle casts in the Scotia Sea and Weddell Sea from the GENERAL SAN MARTIN. Data were collected from 14 December 1963...

  12. Taking tea in the parlour: middle-class formation and gender construction in Nova Scotia and New Brunswick, 1760-1850

    OpenAIRE

    Poole, Ann Judith

    2007-01-01

    Knowledge of tea etiquette was a significant marker of middle-class gentility and contributed to middle-class formation and gender construction in colonial Nova Scotia and New Brunswick. Early middle-class settlers brought tea ware and employed the tea ritual to set standards of gentility that determined social inclusion or exclusion. Tea drinking shifted from a predominantly masculine activity in the late eighteenth century, as commercial and political men met in their parlours over tea, to ...

  13. "Everyone just keeps their eyes closed and their fingers crossed": sexual health communication among black parents and children in Nova Scotia, Canada.

    Science.gov (United States)

    Davis, Antoinette N; Gahagan, Jacqueline C; George, Clemon

    2013-07-22

    Black Canadian youth remain disproportionally affected by an array of social and health issues, including sexually transmitted infections. While research exists in support of the involvement of parents as a key means to prevent or modify harmful behaviours among youth, less is known about how parent-child communication can serve as a prevention intervention strategy within Black families in Canada. This study explores sexual health communication between Black parents and youth in Nova Scotia and identifies facilitators, obstacles and issues that families face in dialoguing about sexual health. Focus groups and in-depth interview sessions were held with a diverse sample of parents of Black youth, health and education professionals, and Black youth in Nova Scotia, as part of a larger study aimed at exploring parent-child communication on sexual health and HIV. The research team worked in partnership with and received feedback from key informants and a community advisory committee throughout the various stages of this study. All sessions were audio-taped with permission and thematic analysis was carried out on the verbatim transcripts. Six key themes emerged from the data analysis in relation to parent-child communication within Black families in Nova Scotia: 1. the gendered nature of [sexual] health communication; 2. fear and uncertainty as obstacles; 3. open and honest dialogue from an early age as a facilitator; 4. media as both a catalyst and a barrier; 5. peers as a catalyst; and 6. time constraints as an obstacle. The findings of this study reveal that parent-child communication regarding sexual health promotion within Black families in Nova Scotia remains varied and is heavily affected by a myriad of intersecting determinants of health faced by Black youth and their parents. Health promotion interventions aimed at fostering and supporting parent-child communication on sexual health must simultaneously target both parents and youth and further, such efforts must

  14. Expanding Free School-based Human Papilloma Virus (HPV Vaccination Programs to Include School-aged Males in Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Hannah Krater-Melamed

    2017-06-01

    Full Text Available Bill 70 (HPV Vaccine Act was presented to the Nova Scotia House of Assembly with the aim of expanding the current Nova Scotia school-based HPV vaccination program to include males. In recent years, increased awareness of HPV and HPV-caused cancers has led to the implementation of school-based female HPV vaccination programs across Canada. Changing guidelines, based on recent evidence, suggest that males should also be included in these programs. Program expansion to include males aims to reduce the prevalence of HPV-causing cancers and their ensuing costs, to promote equal access to healthcare services, and to make Nova Scotia a leader in HPV prevention. Support from the Canadian public and high profile political actors along with pressure from other provinces and interest groups, including the Society of Obstetricians and Gynaecologists of Canada, influenced the passing of the HPV Vaccine Act. In order to implement this reform, the provincial financial commitment to the previous HPV program was expanded to cover the cost of male vaccination.

  15. Shoreface translation and the Holocene stratigraphic record: Examples from Nova Scotia, the Mississippi Delta and eastern Australia

    Science.gov (United States)

    Boyd, Ron; Penland, S.

    1984-01-01

    Classic descriptive models of barrier sedimentation have been developed with data from the Atlantic and Gulf coasts of the United States. These models are dominated by low to moderate rates of relative sea level (RSL) rise and wave energy. Barriers respond by landward recycling of sediment through the mechanism of shoreface retreat. Sedimentation processes on the central coast of New South Wales (N.S.W.), Australia, consist of rapid RSL rise in early Holocene times followed by a stillstand since 6500 B.P. Wave energy is relatively high year-round and sand sources for barrier formation are only found on the inner shelf. Barrier sedimentation on the central coast of N.S.W. exhibits a thick, composite sequence composed of a basal marine transgressive sand overlain by regressive beach and dune facies. The Louisiana coast surrounding the Mississippi delta is underlain by compacting deltaic muds which generate very rapid rates of RSL rise. The Louisiana coast experiences low wave energy punctuated by high-energy tropical and extra-tropical storm events. Barrier sediments accumulate from the erosion of deltaic headlands and undergo a transformation from subaerial barrier island systems to subaqueous shoals located on the inner shelf. Drumlins experience coastal erosion on the Eastern Shore of Nova Scotia and provide a sediment source for compartmented estuary mouth barriers. An ongoing, moderate rise of RSL results from the passage of a glacial forebulge. Wave energy is intermediate between Louisiana and N.S.W. and displays a seasonal pattern dominated by frequent winter storms. Coastal barrier sedimentation is episodic, consisting of a period of beach ridge progradation followed by barrier destruction and re-establishment further landward. The three contrasting sedimentary sequences found in examples from Louisiana, N.S.W. and Nova Scotia indicate that presently available sedimentation models from locations such as the middle Atlantic or Texas coasts of the United States

  16. Early spawning of Antarctic krill in the Scotia Sea is fuelled by “superfluous” feeding on non-ice associated phytoplankton blooms

    Science.gov (United States)

    Schmidt, Katrin; Atkinson, Angus; Venables, Hugh J.; Pond, David W.

    2012-01-01

    The spawning success of Antarctic krill ( Euphausia superba) is generally assumed to depend on substantial winter sea ice extent, as ice biota can serve as a food source during winter/spring and the seasonal ice melt conditions the upper water column for extensive phytoplankton blooms. However, direct observations during spring are rare. Here we studied krill body condition and maturity stage in relation to feeding (i.e. stomach fullness, diet, absorption of individual fatty acids and defecation rate) across the Scotia Sea in November 2006. The phytoplankton concentrations were low at the marginal ice zone (MIZ) in the southern Scotia Sea (Stn. 1, 2, and 3), high in open waters of the Southern Antarctic Circumpolar Current Front (SACCF) in the central Scotia Sea (Stn. 5), and moderate further north (Stn. 6 and 7). Krill had low lipid reserves (˜6.5% of dry mass, DM), low mass:length ratios (˜1.7 mg DM mm -1), and small digestive glands (˜7% of total DM) near the ice edge. The stomachs contained lithogenic particles, diatom debris, and bacterial fatty acids, but low proportions of diatom-indicating fatty acids, which suggest that these krill were feeding on detritus rather than on fresh ice algae. In the SACCF, krill had higher lipid reserves (˜10% of DM), high mass:length ratios (˜2.2 mg DM mm -1), and large digestive glands (˜16% of total DM). Stomach content and tissue composition indicate feeding on diatoms. In the north, moderate food concentrations co-occurred with low lipid reserves in krill, and moderate mass:length ratios and digestive gland sizes. Only in the phytoplankton bloom in the SACCF had the mating season already started and some females were about to spawn. Based on the way krill processed their food at the different stations, we indicate two mechanisms that can lead to fast regeneration of body reserves and oocyte maturation in E. superba. One is "superfluous" feeding at high food concentrations, which maximises the overall nutrient gain

  17. Development of a Medical Humanities Program at Dalhousie University Faculty of Medicine, Nova Scotia, Canada, 1992-2003.

    Science.gov (United States)

    Murray, Jock

    2003-10-01

    The Medical Humanities Program at Dalhousie University Faculty of Medicine in Nova Scotia, Canada, was initiated in 1992 to incorporate the medical humanities into the learning and experiences of medical students. The goal of the program was to gain acceptance as an integral part of the medical school. The program assumed a broad concept of the medical humanities that includes medical history, literature, music, art, multiculturalism, philosophy, epistemology, theology, anthropology, professionalism, history of alternative therapies, writing, storytelling, health law, international medicine, and ethics. Phase I of the program has provided the same elective and research opportunities in the medical humanities that are available to the students in clinical and basic sciences, and has encouraged and legitimized the involvement of the humanities in the life and learning of the medical student through a wide array of programs and activities. Phase II will focus on further incorporation of the humanities into the curriculum. Phase III will be the development of a graduate program in medical humanities to train more faculty who will incorporate the humanities into their teaching and into the development of education programs.

  18. Assessing the potential for isotopic partitioning of soil respiration at research sites in Nova Scotia and Newfoundland

    Energy Technology Data Exchange (ETDEWEB)

    Risk, D.; Kellman, L.; Black, M. [Saint Francis Xavier Univ., Antigonish, NS (Canada). Environmental Sciences Research Centre

    2005-07-01

    The stable isotope ratios of carbon and oxygen in different tree species were studied with respect to different tissues, at different points within the tree, through soil profiles and in carbon dioxide respired from laboratory incubations. Although isotopic methods of partitioning autotrophic and heterotrophic soil respiration have been used with some success, stable isotopic methods are complicated by the fact that carbon isotope fractionations are small in natural systems, and radiocarbon techniques are time and equipment intensive. Studies that use isotopic analysis opportunistically, such as in C3/C4 transitional systems, have proven to be the most successful. Previously unexploited opportunities have the potential to be used for stable isotope-based partitioning in natural systems if the autotrophic/heterotrophic process distribution in the profile is well understand and if there is good process resolution and concurrent analyses using physical partitioning methods such as trenches. This study explored the different paths of opportunity in terms of background isotopic characterization that is being carried out for an existing network of carbon flux research sites in eastern Nova Scotia and in western Newfoundland. The new continuous flow-isotope ratio mass spectrometer (CF-IRMS) at the Environmental Earth Sciences Laboratory at St. Francis Xavier University was used for the isotopic analyses. The isotopic information will be evaluated for potential partitioning opportunities, considering the combination of approaches that will give the best chances of success. Isotopic partitioning trials will take place at suitable sites.

  19. Serum C-reactive protein concentrations in Nova Scotia Duck Tolling Retrievers with immune-mediated rheumatic disease.

    Science.gov (United States)

    Bremer, Hanna Dorotea; Hillström, Anna; Kånåhols, Malin; Hagman, Ragnvi; Hansson-Hamlin, Helene

    2017-04-17

    Nova Scotia Duck Tolling Retrievers (NSDTRs) are a dog breed often affected by immune-mediated rheumatic disease (IMRD), a disorder characterised by chronic stiffness and joint pain. Most, but not all, dogs with IMRD, have antinuclear antibodies (ANA), which are also commonly present in the autoimmune disease systemic lupus erythematosus (SLE). The clinical and diagnostic findings of IMRD indicate that it is an SLE-related disorder. C-reactive protein (CRP), an acute phase protein, is a quantitative marker of inflammation for many diseases and is used for diagnosing and monitoring systemic inflammation in both humans and dogs. However, in human SLE, CRP concentrations are often elevated but correlate poorly with disease activity; they can be low in individual patients with active disease. The aim of the study was to investigate CRP in a group of NSDTRs with the SLE-related disorder IMRD. The hypothesis was that CRP concentrations would be increased in dogs with IMRD compared to healthy dogs, but that the increase would be mild. Serum CRP concentrations were measured in 18 IMRD-affected NSDTRs and 19 healthy control NSDTRs using two different canine-specific CRP assays. Dogs with IMRD and ANA had higher CRP concentrations than the control dogs, but the concentrations were below the clinical decision limit for systemic inflammation for most of the IMRD dogs. These results indicate that CRP concentrations were increased in dogs with IMRD and ANA, but the increase was mild, similar to what has been observed in human SLE.

  20. Effects of workplace policy on continuing professional development: the case of occupational therapy in Nova Scotia, Canada.

    Science.gov (United States)

    Townsend, Elizabeth; Sheffield, Suzanne Le-May; Stadnyk, Robin; Beagan, Brenda

    2006-04-01

    Continuing professional development is essential for professionals to remain competent, and for effective recruitment and retention. This paper reports a qualitative study of the effects of workplace policy on continuing professional development on a small, dispersed profession in a resource-challenged province, using the case example of occupational therapy in Nova Scotia. The study used a multi-methods design, theoretically based on institutional ethnography. Methods were critical appraisal of the literature, interview and focus group data collection with 28 occupational therapists and 4 health services administrators, and a review of workplace policy. The study identified a policy wall. Notable policies were those which defined who is responsible for continuing professional development, and which limited employee benefits and work flexibility options for those with family duties. It appears that a female-dominated profession, such as occupational therapy, may also face gender-based challenges. Suggestions are offered for workplace policy makers, unions, provincial regulatory organizations, and health professionals. The findings are generally applicable to any small, dispersed health profession operating in resource-challenged conditions.

  1. Pilot study investigating ambient air toxics emissions near a Canadian kraft pulp and paper facility in Pictou County, Nova Scotia.

    Science.gov (United States)

    Hoffman, Emma; Guernsey, Judith R; Walker, Tony R; Kim, Jong Sung; Sherren, Kate; Andreou, Pantelis

    2017-09-01

    Air toxics are airborne pollutants known or suspected to cause cancer or other serious health effects, including certain volatile organic compounds (VOCs), prioritized by the US Environmental Protection Agency (EPA). While several EPA-designated air toxics are monitored at a subset of Canadian National Air Pollution Surveillance (NAPS) sites, Canada has no specific "air toxics" control priorities. Although pulp and paper (P&P) mills are major industrial emitters of air pollutants, few studies quantified the spectrum of air quality exposures. Moreover, most NAPS monitoring sites are in urban centers; in contrast, rural NAPS sites are sparse with few exposure risk records. The objective of this pilot study was to investigate prioritized air toxic ambient VOC concentrations using NAPS hourly emissions data from a rural Pictou, Nova Scotia Kraft P&P town to document concentration levels, and to determine whether these concentrations correlated with wind direction at the NAPS site (located southwest of the mill). Publicly accessible Environment and Climate Change Canada data (VOC concentrations [Granton NAPS ID: 31201] and local meteorological conditions [Caribou Point]) were examined using temporal (2006-2013) and spatial analytic methods. Results revealed several VOCs (1,3-butadiene, benzene, and carbon tetrachloride) routinely exceeded EPA air toxics-associated cancer risk thresholds. 1,3-Butadiene and tetrachloroethylene were significantly higher (p towns and contribute to poor health in nearby communities.

  2. Comparison of Bayesian and frequentist approaches in modelling risk of preterm birth near the Sydney Tar Ponds, Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Canty Angelo

    2007-09-01

    Full Text Available Abstract Background This study compares the Bayesian and frequentist (non-Bayesian approaches in the modelling of the association between the risk of preterm birth and maternal proximity to hazardous waste and pollution from the Sydney Tar Pond site in Nova Scotia, Canada. Methods The data includes 1604 observed cases of preterm birth out of a total population of 17559 at risk of preterm birth from 144 enumeration districts in the Cape Breton Regional Municipality. Other covariates include the distance from the Tar Pond; the rate of unemployment to population; the proportion of persons who are separated, divorced or widowed; the proportion of persons who have no high school diploma; the proportion of persons living alone; the proportion of single parent families and average income. Bayesian hierarchical Poisson regression, quasi-likelihood Poisson regression and weighted linear regression models were fitted to the data. Results The results of the analyses were compared together with their limitations. Conclusion The results of the weighted linear regression and the quasi-likelihood Poisson regression agrees with the result from the Bayesian hierarchical modelling which incorporates the spatial effects.

  3. The influence of intrinsic and extrinsic job values on turnover intention among continuing care assistants in Nova Scotia.

    Science.gov (United States)

    Dill, Donna M; Keefe, Janice M; McGrath, Daniel S

    2012-01-01

    This article examines the influence that intrinsic and extrinsic job values have on the turnover intention of continuing care assistants (CCAs) who work either in home care or facility-based care in Nova Scotia (n = 188). Factor analysis of job values identified three latent job values structures: "compensation and commitment," "flexibility and opportunity," and "positive work relationships." Using binary logistic regression, we examined the predictive utility of these factors on two indices of turnover intention. Regression results indicate that, in general, job values constructs did not significantly predict turnover intention when controlling for demographics and job characteristics. However, a trend was found for the "positive work relationships" factor in predicting consideration of changing employers. In addition, CCAs who work in facility-based care were significantly more likely to have considered leaving their current employer. With projected increases in the demand for these workers in both home and continuing care, more attention is needed to identify and address factors to reduce turnover intention.

  4. Determining appropriate wind turbine setback distances: Perspectives from municipal planners in the Canadian provinces of Nova Scotia, Ontario, and Quebec

    International Nuclear Information System (INIS)

    Watson, Ian; Betts, Stephen; Rapaport, Eric

    2012-01-01

    This paper uses a series of interviews to investigate how municipal planners in three Canadian provinces (Nova Scotia, Quebec, and Ontario) influence setbacks that regulate appropriate locations for wind turbines. Setbacks are provisions in local land use policies that dictate required separation distances between wind turbines and other land uses. Results of the study indicate that planners are not using a consistent method to ascertain appropriate distances and are often constrained by a lack of experience, resources, and expertise. These findings have important implications for wind energy regulation. Setbacks are intended to reasonably protect the public from the impacts of wind turbines, while allowing for some development. Municipalities in Canada may be best placed to consider local impacts of wind power, but the challenges identified raise concerns about potential arbitrariness. Setbacks that are unjustifiably high can unnecessarily close off territory and limit the ability to reach renewable energy targets. Taking regulatory power away from municipalities, as has happened in Ontario, can facilitate achievement of provincial targets, but may also increase opposition to projects at the local level. - Highlights: ► Inconsistent methods used for establishing wind turbine setbacks. ► Most common method used is a review of other setback by-laws. ► Barriers to implementation of setbacks include knowledge, resources, and consensus. ► Recommend documentation of planning process in setting setbacks.

  5. The ESASSI-08 cruise in the South Scotia Ridge region: preliminary analysis of hydrodynamic and biogeochemical data

    Science.gov (United States)

    Gomis, D.; Flexas, M. M.; Palmer, M.; Jordà, G.; Orsi, A. H.; Yvon-Lewis, S. A.

    2009-04-01

    The ESASSI-08 oceanographic cruise carried out in January 2008 was the major milestone of ESASSI, the Spanish component of SASSI (a core project of the International Polar Year devoted to study the shelf-slope exchanges in different locations of Antarctica). The sampling strategy of the cruise consisted of 11 full-depth CTD/ADCP sections across the northern and southern slope of the South Scotia Ridge (SSR), between Elephant and Orkney Islands. The sections extend from shelf waters to open sea and the profiles were gathered at an unprecedented spatial resolution over the slope (about 2 nm). Water samples for chemical and biological analysis were also collected at each station; the analyzed parameters include trace gases (CFCs), oxygen isotopes, carbon-related parameters, and nutrients. In this presentation we show the overall distribution of the main variables across the different sections. Namely, we present: a water mass analysis (in terms of potential temperature, salinity and neutral density), estimates of velocities and fluxes across different transects and distributions of biogeochemical parameters. The ultimate aims of the ESASSI project are: 1) to elucidate the fate of the ASF when it enters the SSR from the Weddell Sea; 2) to estimate the shelf-slope exchanges for different parameters; and 3) to quantify the importance of the ventilation associated with intermediate waters flowing over the SSR with respect to the ventilation associated with bottom waters that are blocked by the SSR and flow around the Orkney Plateau.

  6. A documentation of structures in unconsolidated sediments along the north shore of the Minas Basin, Nova Scotia

    International Nuclear Information System (INIS)

    Stokes, T.R.

    1988-12-01

    During the summer of 1987 the north shore of the Minas Basin, Nova Scotia, was examined for evidence of structures in unconsolidated sediments. This shoreline exposes the eastern extension of the Cobequid-Chedabucto fault system which was active from the Devonian until at least the Permian, and possible into the Mesozoic. The primary aim of the study was to document, measure and record any structures in unconsolidated sediments. In all, thirty-four structure locations were found; of these, twenty-nine were in glacial outwash deltas, the results of the Late Wisconsinan ice retreat. The most important structures include: 1) conjugate normal faults in Advocate Harbour sands and muds at East Finney Brook; 2) associated faults and folds in the Advocate Harbour bottomset muds at Lower Five Islands; and 3) major convolutions in Advocate Harbour bottomset muds at Economy Point. The convolutions are the results of seismic shaking which either postdated delta formation or triggered synsedimentary slumping. The faults and folds at Lower Five Islands were formed by extension related to either delta slumping or possible bedrock movement. The conjugate fault set at East Finney Brook is the result of an extensional event probably caused by late NE-SW normal fault reactivation. It is unclear whether this reactivation is the result of glacial rebound or neotectonic movement

  7. A participatory approach to sustainable energy strategy development in a carbon-intensive jurisdiction: The case of Nova Scotia

    International Nuclear Information System (INIS)

    Adams, Michelle; Wheeler, David; Woolston, Genna

    2011-01-01

    The need for governments to reduce the exposure of energy consumers to future increases in fossil fuel prices places urgent pressure on policy-makers to deliver fundamental transformations in energy strategies, particularly in jurisdictions with high dependency on fossil fuel sources (). This transformation is unlikely without a high level of stakeholder engagement in the policy development process. This paper describes two policy development processes recently undertaken in Nova Scotia in which the inclusion of stakeholder views was central to the approach. The first delivered a new institutional framework for electricity energy efficiency involving the inception of an independent performance-based administrator. The second required the delivery of a strategy to significantly increase renewable energy generation in the Province. It involved recommendations for changes in institutional arrangements, financial incentives and technological options. This process was followed by new commitments to renewable energy developments, new infrastructure for the importation of hydro-electricity, and the announcement of FITs for ocean energy. In both cases, recommendations were made by an independent academic institution, and the Government responded directly to a majority of recommendations. The paper concludes with a discussion of lessons learned and the implications for future energy policy making in carbon-intensive jurisdictions. - Research highlights: → Fundamental transformations in energy policy require stakeholder engagement to be successful. → We describe two policy development processes where stakeholder views were key considerations. → The first delivered a new institutional framework for electricity energy efficiency. → The second delivered a strategy to significantly increase renewable energy generation. → In each case, the Government directly responded to the majority of recommendations.

  8. Identifying the sources driving observed PM2.5 temporal variability over Halifax, Nova Scotia, during BORTAS-B

    Directory of Open Access Journals (Sweden)

    M. D. Gibson

    2013-07-01

    Full Text Available The source attribution of observed variability of total PM2.5 concentrations over Halifax, Nova Scotia, was investigated between 11 July and 26 August 2011 using measurements of PM2.5 mass and PM2.5 chemical composition (black carbon, organic matter, anions, cations and 33 elements. This was part of the BORTAS-B (quantifying the impact of BOReal forest fires on Tropospheric oxidants using Aircraft and Satellites experiment, which investigated the atmospheric chemistry and transport of seasonal boreal wildfire emissions over eastern Canada in 2011. The US EPA Positive Matrix Factorization (PMF receptor model was used to determine the average mass (percentage source contribution over the 45 days, which was estimated to be as follows: long-range transport (LRT pollution: 1.75 μg m−3 (47%; LRT pollution marine mixture: 1.0 μg m−3 (27.9%; vehicles: 0.49 μg m−3 (13.2%; fugitive dust: 0.23 μg m−3 (6.3%; ship emissions: 0.13 μg m−3 (3.4%; and refinery: 0.081 μg m−3 (2.2%. The PMF model describes 87% of the observed variability in total PM2.5 mass (bias = 0.17 and RSME = 1.5 μg m−3. The factor identifications are based on chemical markers, and they are supported by air mass back trajectory analysis and local wind direction. Biomass burning plumes, found by other surface and aircraft measurements, were not significant enough to be identified in this analysis. This paper presents the results of the PMF receptor modelling, providing valuable insight into the local and upwind sources impacting surface PM2.5 in Halifax and a vital comparative data set for the other collocated ground-based observations of atmospheric composition made during BORTAS-B.

  9. A participatory approach to sustainable energy strategy development in a carbon-intensive jurisdiction: The case of Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    Adams, Michelle, E-mail: adamsm@dal.c [School for Resource and Environmental Studies, Dalhousie University, 6100 University Avenue, Suite 5010, Halifax, NS, B3H 3J5 (Canada); Wheeler, David [Plymouth Business School, University of Plymouth, Cookworthy Building, Drake Circus, Plymouth, Devon PL4 8AA (United Kingdom); Woolston, Genna [School for Resource and Environmental Studies, Dalhousie University, 6100 University Avenue, Suite 5010, Halifax, NS, B3H 3J5 (Canada)

    2011-05-15

    The need for governments to reduce the exposure of energy consumers to future increases in fossil fuel prices places urgent pressure on policy-makers to deliver fundamental transformations in energy strategies, particularly in jurisdictions with high dependency on fossil fuel sources (). This transformation is unlikely without a high level of stakeholder engagement in the policy development process. This paper describes two policy development processes recently undertaken in Nova Scotia in which the inclusion of stakeholder views was central to the approach. The first delivered a new institutional framework for electricity energy efficiency involving the inception of an independent performance-based administrator. The second required the delivery of a strategy to significantly increase renewable energy generation in the Province. It involved recommendations for changes in institutional arrangements, financial incentives and technological options. This process was followed by new commitments to renewable energy developments, new infrastructure for the importation of hydro-electricity, and the announcement of FITs for ocean energy. In both cases, recommendations were made by an independent academic institution, and the Government responded directly to a majority of recommendations. The paper concludes with a discussion of lessons learned and the implications for future energy policy making in carbon-intensive jurisdictions. - Research highlights: {yields} Fundamental transformations in energy policy require stakeholder engagement to be successful. {yields} We describe two policy development processes where stakeholder views were key considerations. {yields} The first delivered a new institutional framework for electricity energy efficiency. {yields} The second delivered a strategy to significantly increase renewable energy generation. {yields} In each case, the Government directly responded to the majority of recommendations.

  10. Deep seismic studies of conjugate profiles from the Nova Scotia - Moroccan and the Liguro-Provencal margin pairs

    Science.gov (United States)

    Klingelhoefer, F.; Biari, Y.; Sahabi, M.; Aslanian, D.; Philippe, S.; Schnabel, M.; Moulin, M.; Louden, K. E.; Funck, T.; Reichert, C. J.

    2014-12-01

    The structure of conjugate passive margins provides information about rifting styles, opening of an ocean and formation of it's associated sedimentary basins. In order to distinguish between tectonic inheritance and structures directly related to rifting of passive margins conjugate profiles have to be acquired on margins on diverse locations and different ages. In this study we use new and existing reflection and wide-angle seismic data from two margin pairs, the 200 Ma year old Nova-Scotia - Morocco margin pair and the only 20 Ma Gulf of Lions - Sardinia margin pair. On both margin pairs wide-angle seismic data combined with reflection seismic data were acquired on conjugate profiles on sea and extended on land. Forward modelling of the deep crustal structure along the four transects indicates that a high velocity zone (HVZ) (> 7.2 km/s) is present at the base of the lower crust on all four margins along the ocean-continental transition zone (OCT). This may represent either exhumed upper mantle material or injection of upper mantle material into proto-oceanic crust at the onset of sea-floor spreading. However the width of the HVZ might strongly differ between conjugates, which may be the result of tectonic inheritance, for example the presence of ancient subduction zones or orogens. Both margin pairs show a similar unthinned continental crustal thickness. Crustal thinning and upper-to-lower crustal thickness vary between margin pairs, but remain nearly symmetric on conjugate profiles and might therefore depend on the structure and mechanical properties of the original continental crust. For the Mediterranean margin pair, the oceanic crust is similar on both sides, with a thickness of only 4-5 km. For the Atlantic margin pair, oceanic crustal thickness is higher on the Moroccan Margin, a fact that can be explained by either asymmetric spreading or by the volcanic underplating, possibly originating from the Canary Hot Spot.

  11. Is the minimum enough? Affordability of a nutritious diet for minimum wage earners in Nova Scotia (2002-2012).

    Science.gov (United States)

    Newell, Felicia D; Williams, Patricia L; Watt, Cynthia G

    2014-05-09

    This paper aims to assess the affordability of a nutritious diet for households earning minimum wage in Nova Scotia (NS) from 2002 to 2012 using an economic simulation that includes food costing and secondary data. The cost of the National Nutritious Food Basket (NNFB) was assessed with a stratified, random sample of grocery stores in NS during six time periods: 2002, 2004/2005, 2007, 2008, 2010 and 2012. The NNFB's cost was factored into affordability scenarios for three different household types relying on minimum wage earnings: a household of four; a lone mother with three children; and a lone man. Essential monthly living expenses were deducted from monthly net incomes using methods that were standardized from 2002 to 2012 to determine whether adequate funds remained to purchase a basic nutritious diet across the six time periods. A 79% increase to the minimum wage in NS has resulted in a decrease in the potential deficit faced by each household scenario in the period examined. However, the household of four and the lone mother with three children would still face monthly deficits ($44.89 and $496.77, respectively, in 2012) if they were to purchase a nutritiously sufficient diet. As a social determinant of health, risk of food insecurity is a critical public health issue for low wage earners. While it is essential to increase the minimum wage in the short term, adequately addressing income adequacy in NS and elsewhere requires a shift in thinking from a focus on minimum wage towards more comprehensive policies ensuring an adequate livable income for everyone.

  12. Apparent survival of adult Leach's Storm-petrels (Oceanodroma leucorhoa breeding on Bon Portage Island, Nova Scotia

    Directory of Open Access Journals (Sweden)

    Danielle T. Fife

    2015-12-01

    Full Text Available Populations of Leach's Storm-petrel (Oceanodroma leucorhoa; hereafter storm-petrel, one of the most widespread procellariiform seabirds in the world, appear to be declining in many parts of their breeding range. As part of a regional effort to assess status of storm-petrel colonies in eastern North America, we estimated apparent survival and recapture probabilities from 2009 to 2014 for adults on Bon Portage Island (43° 28' N, 65° 44' W, located off the southwestern coast of Nova Scotia, Canada. Mean annual survival estimated for this colony was low (0.78 ± 0.04 compared with other procellariiforms, e.g., > 0.90 for many albatrosses and petrels. Storm-petrels that were fitted with very high frequency (VHF radio tags had an average of 0.11 ± 0.05 (95% confidence interval [CI] = 0.01 to 0.21 higher survival probabilities than those that were not, possibly because VHF tags were attached to known, established breeders. There was weak evidence that survival was reduced by an average of 0.07 ± 0.04 for storm-petrels in study plots that were occupied by Herring Gulls (Larus argentatus and their chicks; however, this result was not statistically significant (95% CI: -0.15 to 0.02. Low adult survival is an early indication that this important colony may be under stress. However, further work is needed to determine if the colony is indeed declining and, if so, to determine the cause(s of the decline so that they may be addressed.

  13. Protocol for determining primary healthcare practice characteristics, models of practice and patient accessibility using an exploratory census survey with linkage to administrative data in Nova Scotia, Canada.

    Science.gov (United States)

    Marshall, Emily Gard; Gibson, Richard J; Lawson, Beverley; Burge, Frederick

    2017-03-16

    There is little evidence on how primary care providers (PCPs) model their practices in Nova Scotia (NS), Canada, what services they offer or what accessibility is like for the average patient. This study will create a database of all family physicians and primary healthcare nurse practitioners in NS, including information about accessibility and the model of care in which they practice, and will link the survey data to administrative health databases. 3 census surveys of all family physicians, primary care nurse practitioners (ie, PCPs) and their practices in NS will be conducted. The first will be a telephone survey conducted during typical daytime business hours. At each practice, the person answering the telephone will be asked questions about the practice's accessibility and model of care. The second will be a telephone survey conducted after typical daytime business hours to determine what out-of-office services PCP practices offer their patients. The final will be a tailored fax survey that will collect information that could not be obtained in the first 2 surveys plus new information on scope of practice, practice model and willingness to participate in research. Survey data will be linked with billing data from administrative health databases. Multivariate regression analysis will be employed to assess whether access and availability outcome variables are associated with PCP and model of practice characteristics. Negative binomial regression analysis will be employed to assess the association between independent variables from the survey data and health system use outcomes from administrative data. This study has received ethical approval from the Nova Scotia Health Authority and the Health Data Nova Scotia Data Access Committee. Dissemination approached will include stakeholder engagement at local and national levels, conference presentations, peer-reviewed publications and a public website. Published by the BMJ Publishing Group Limited. For permission to

  14. New tentacled leech Ceratobdella quadricornuta n. g., n. sp. (Hirudinida: Piscicolidae) parasitic on the starry skate Raja georgiana Norman from the Scotia Sea, Antarctica.

    Science.gov (United States)

    Utevsky, Andrei; Gordeev, Ilya

    2015-07-01

    A new fish leech Ceratobdella quadricornuta n. g., n. sp. (Hirudinida: Piscicolidae), a parasite of the Antarctic skate Raja georgiana Norman (Rajiformes: Rajidae) collected between the Falkland Islands and South Georgia Island in the Scotia Sea, is described and compared with related genera. Ceratobdella quadricornuta is characterised by an uncommon appearance of its anterior sucker bearing four well-developed tentacles and a unique combination of features of the reproductive and digestive systems: crop and intestine equally developed, posterior crop caeca separated; accessory glands, conductive tissue and external copulatory area lacking; common part of ejaculatory ducts (common atrium) voluminous and muscular, male copulatory bursa short, small ovisacs opening into female copulatory bursa (vagina).

  15. Spilt milk: an inter-sectoral partnership that failed to advance milk security for low-income lone mothers in Nova Scotia, Canada.

    Science.gov (United States)

    McIntyre, Lynn; Glanville, N Theresa; Hilchie-Pye, Andrea

    2011-03-01

    Canadian agricultural policy supports higher milk prices. Consequently, poor families lack sufficient funds to purchase adequate quantities of milk. Low-income lone mothers in the Canadian province of Nova Scotia suggested their preferred strategies for improved access to milk. We then built inter-sectoral support for a policy intervention to address their recommendations. Our research-to-action process led to a policy dialogue focusing on an electronic smart card that would permit the delivery of lower-priced milk to poor households. While all agreed that milk insecurity was an important issue, the project ultimately failed because of the entrenched positions of influential stakeholder groups.

  16. Earliest history of coal mining and grindstone quarrying at Joggins, Nova Scotia, and its implications for the meaning of the place name Joggins

    Energy Technology Data Exchange (ETDEWEB)

    Falcon-Lang, H.J. [Bristol Univ., Bristol (United Kingdom). Dept. of Earth Sciences; London Univ., Egham (United Kingdom). Dept. of Earth Sciences

    2009-07-01

    The Joggins Section is a carboniferous succession located on the southeastern shore of the Bay of Fundy in Nova Scotia. The explorer Charles Lyell wrote about the Section's coal-bearing strata and extraordinary fossil forests in 1843. This paper reviewed earlier studies and literature related to the region in order to discuss coal mining and grindstone quarrying in the region in the late 1600s. Mineral exploration of the region began soon after French settlers arrived in 1604, and the earliest record of coal-mining occurred in 1639. References to the Joggins Section occurred in the diary of Samuel Pepys. Detailed maps from 1686 depict coastal outcrop belts of coal-bearing strata. Other records describe illicit trade of coal between Joggins and New England. A travelogue in 1731 described the mines and their location. A state-sponsored British coal mine was proposed in 1730. However, the venture was abandoned after attacks by angry local residents. Later studies of the region described the coal as being of inferior quality. The General Mining Association of Britain became lessees of all the mines and minerals in the province of Nova Scotia in 1827. However, several bootleg operations continued to mine the coals. It was concluded that a thriving grindstone industry in the region filled gaps in the local economy caused by the periods of mine closures. 93 refs., 15 figs.

  17. Earliest history of coal mining and grindstone quarrying at Joggins, Nova Scotia, and its implications for the meaning of the place name Joggins

    International Nuclear Information System (INIS)

    Falcon-Lang, H.J.; London Univ., Egham

    2009-01-01

    The Joggins Section is a carboniferous succession located on the southeastern shore of the Bay of Fundy in Nova Scotia. The explorer Charles Lyell wrote about the Section's coal-bearing strata and extraordinary fossil forests in 1843. This paper reviewed earlier studies and literature related to the region in order to discuss coal mining and grindstone quarrying in the region in the late 1600s. Mineral exploration of the region began soon after French settlers arrived in 1604, and the earliest record of coal-mining occurred in 1639. References to the Joggins Section occurred in the diary of Samuel Pepys. Detailed maps from 1686 depict coastal outcrop belts of coal-bearing strata. Other records describe illicit trade of coal between Joggins and New England. A travelogue in 1731 described the mines and their location. A state-sponsored British coal mine was proposed in 1730. However, the venture was abandoned after attacks by angry local residents. Later studies of the region described the coal as being of inferior quality. The General Mining Association of Britain became lessees of all the mines and minerals in the province of Nova Scotia in 1827. However, several bootleg operations continued to mine the coals. It was concluded that a thriving grindstone industry in the region filled gaps in the local economy caused by the periods of mine closures. 93 refs., 15 figs

  18. Report and recommendations to the Minister regarding the environmental assessment report for Polsky Energy Corporation's proposed undertaking Brooklyn Energy Centre, Queens County, Nova Scotia

    International Nuclear Information System (INIS)

    Beanlands, G.; Glover, D.; Beviss, H.

    1993-01-01

    A public consultation review was undertaken to assess the suitability and environmental compatibility of Polsky Energy Corporation's proposal for a wood-fired cogeneration plant in Brooklyn, Nova Scotia. The plant would supply 21.3 MW of power to the provincial utility and steam to a local paper company. Public hearings were held in January 1993 and presentations were received from the project proponent and various intervenors. The concerns identified in the hearing included adequacy of the supply of wood wastes and the percentage of supplementary fuels required; air emissions and water-related effluents; ash disposal; monitoring; noise and traffic; socioeconomic impacts; and decommissioning. The hearing panel, appointed by the Nova Scotia Environmental Control Council, considered all the information received and concluded that the proposed facility will not cause significant or unacceptable risks to the natural and social environments of the surrounding community. This is contingent upon effective monitoring, appropriate guidance by regulatory agencies, and opportunities for continued liaison with the community. Conditions recommended by the panel include no operation of the plant using less than 70% wood as the principal fuel supply; conducting of a fuel audit every two years; reduction of the safety risk associated with the projected increase in truck traffic; continuous monitoring of stack emissions; and a requirement for a decommissioning plan as part of the permitting process. 3 refs., 1 fig

  19. Physicians’ attitudes towards office-based delivery of methadone maintenance therapy: results from a cross-sectional survey of Nova Scotia primary-care physicians

    Directory of Open Access Journals (Sweden)

    Dooley Jessica

    2012-06-01

    Full Text Available Abstract Background Approximately 90,000 Canadians use opioids each year, many of whom experience health and social problems that affect the individual user, families, communities and the health care system. For those who wish to reduce or stop their opioid use, methadone maintenance therapy (MMT is effective and supporting evidence is well-documented. However, access and availability to MMT is often inconsistent, with greater inequity outside of urban settings. Involving community based primary-care physicians in the delivery of MMT could serve to expand capacity and accessibility of MMT programs. Little is known, however, about the extent to which MMT, particularly office-based delivery, is acceptable to physicians. The aim of this study is to survey physicians about their attitudes towards MMT, particularly office-based delivery, and the perceived barriers and facilitators to MMT delivery. Methods In May 2008, facilitated by the College of Physicians and Surgeons of Nova Scotia, a cross-sectional, e-mail survey of 950 primary-care physicians practicing in Nova Scotia, Canada was administered via the OPINIO on-line survey software, to assess the acceptability of office-based MMT. Logistic regressions, adjusted for physician sociodemographic characteristics, were used to examine the association between physicians’ willingness to participate in office-based MMT, and a series of measures capturing physician attitudes and knowledge about treatment approaches, opioid use, and methadone, as well as perceived barriers to MMT. Results Overall, 19.8% of primary-care physicians responded to the survey, with 56% who indicated that they would be willing to be involved in MMT under current or similar circumstances; however, willingness was associated with numerous attitudinal and systemic factors. The barriers to involvement in MMT that were frequently cited included a lack of training or experience in MMT, lack of support services, and potential

  20. Bioproductivity in the Southern Ocean since the last Interglacial - new high-resolution biogenic opal flux records from the Scotia Sea

    Science.gov (United States)

    Sprenk, D.; Weber, M. E.; Kuhn, G.; Rosén, P.; Röhling, H.-G.

    2012-04-01

    The Southern Ocean plays an important role in transferring CO2 via wind-induced upwelling from the deep sea to the atmosphere. It is therefore one of the key areas to study climate change. Bioproductivity in the Southern Ocean is mostly influenced by the extent of sea ice, upwelling of cold nutrient- and silica-rich water, and the availability of light. Biogenic opal (BSi) is a significant nutrient in the Southern Ocean, and according to recent investigations only marginally affected by preservation changes. It can therefore be used as bioproductivity proxy. Here we present several methods to determine BSi, discuss them and put the results into context with respect to regional bioproductivity changes in Southern Ocean during the last glacial cycle. We studied deep-sea sediment core sites MD07-3133 and MD07-3134 from the central Scotia Sea with extraordinary high sedimentation rates of up to 2.1 to 1.2 m/kyr, respectively covering the last 92.5 kyr. BSi leaching according to Müller & Schneider (1993) is very time-consuming and expensive, so we measured only 253 samples from large-amplitude variation core sections. In addition, we determined BSi using non-destructive measurements of sediment colour b*, wet-bulk density, and Ti/Si count ratios. Furthermore, we provide the first attempts to estimate BSi in marine sediment using Fourier transform infrared spectroscopy (FTIRS), a cost-efficient method, which requires only 11 mg of sediment. All estimation methods capture the main BSi trends, however FTIRS seems to be the most promising one. In the central Scotia Sea, south of the modern Antarctic Polar Front, the BSi flux reflects a relatively complicated glacial-to-interglacial pattern with large-amplitude, millennial-scale fluctuations in bioproductivity. During Antarctic Isotopic Maxima, BSi fluxes were generally increased. Lowest bioproductivity occur at the Last Glacial Maximum, while upwelling of mid-depth water was reduced, atmospheric CO2 low, and sea-ice cover

  1. Composition of hydrothermal fluids and mineralogy of associated chimney material on the East Scotia Ridge back-arc spreading centre

    Science.gov (United States)

    James, Rachael H.; Green, Darryl R. H.; Stock, Michael J.; Alker, Belinda J.; Banerjee, Neil R.; Cole, Catherine; German, Christopher R.; Huvenne, Veerle A. I.; Powell, Alexandra M.; Connelly, Douglas P.

    2014-08-01

    The East Scotia Ridge is an active back-arc spreading centre located to the west of the South Sandwich island arc in the Southern Ocean. Initial exploration of the ridge by deep-tow surveys provided the first evidence for hydrothermal activity in a back-arc setting outside of the western Pacific, and we returned in 2010 with a remotely operated vehicle to precisely locate and sample hydrothermal sites along ridge segments E2 and E9. Here we report the chemical and isotopic composition of high- and low-temperature vent fluids, and the mineralogy of associated high-temperature chimney material, for two sites at E2 (Dog’s Head and Sepia), and four sites at E9 (Black & White, Ivory Tower, Pagoda and Launch Pad). The chemistry of the fluids is highly variable between the ridge segments. Fluid temperatures were ∼350 °C at all vent sites except Black & White, which was significantly hotter (383 °C). End-member chloride concentrations in E2 fluids (532-536 mM) were close to background seawater (540 mM), whereas Cl in E9 fluids was much lower (98-220 mM) indicating that these fluids are affected by phase separation. Concentrations of the alkali elements (Na, Li, K and Cs) and the alkaline earth elements (Ca, Sr and Ba) co-vary with Cl, due to charge balance constraints. Similarly, concentrations of Mn and Zn are highest in the high Cl fluids but, by contrast, Fe/Cl ratios are higher in E9 fluids (3.8-8.1 × 10-3) than they are in E2 fluids (1.5-2.4 × 10-3) and fluids with lowest Cl have highest Cu. Although both ridge segments are magmatically inflated, there is no compelling evidence for input of magmatic gases to the vent fluids. Fluid δD values range from 0.2‰ to 1.5‰, pH values (3.02-3.42) are not especially low, and F concentrations (34.6-54.4 μM) are lower than bottom seawater (62.8 μM). The uppermost sections of conjugate chimney material from E2, and from Ivory Tower and Pagoda at E9, typically exhibit inner zones of massive chalcopyrite enclosed

  2. Chemotaxonomy for naturally macerated tree-fern cuticles (Medullosales and Marattiales), Carboniferous Sydney and Mabou Sub-Basins, Nova Scotia, Canada

    Science.gov (United States)

    Zodrow, E.L.; Mastalerz, Maria

    2001-01-01

    Naturally macerated cuticles (NMC) and one synangium, representing medullosalean and marattialean tree-fern species, from two Carboniferous coalfields in Nova Scotia, Canada, are investigated. The samples were analyzed by infrared spectroscopy (FTIR), and by pyrolysis-gas chromatograph/mass spectrometry (py-Gc/Ms) techniques in search for chemical signatures that would help in developing a chemotaxonomic classification of Carboniferous fern species, assuming genetically dependent make-up of cuticles. FTIR-derived CH2/CH3 ratios, in conjunction with contributions from carboxyl groups, demonstrated a better potential for discriminating between medullosalean genera and species than molecular signatures obtained by py-Gc/Ms. However, the latter provided better data for differentiating medullosalean from marattialean tree ferns as a group. Changes in the chemical make-up of naturally macerated cuticles due to sample preparation are discussed. ?? 2001 Elsevier Science B.V. All rights reserved.

  3. Arts, Crafts, and Rural Rehabilitation: the Sisters of Charity, Halifax, and Vocational Education in Terence Bay, Nova Scotia, 1938-1942

    Directory of Open Access Journals (Sweden)

    Sasha MULLALLY

    2018-01-01

    Full Text Available Responding to rural poverty associated with the declining fishery, the rise of industrial capitalism, and the impact of the Great Depression, the Sisters of Charity, Halifax, implemented a vocational training program in weaving and carpentry in the small community of Terence Bay, Nova Scotia in 1938. Senator William Dennis, a proponent of the New Democracy Movement, financed the program. Because the Sisters based their claims to success on observed behavioural changes among the residents of Terence Bay, the program can be seen as an example of liberal therapeutics in education, a model that placed emphasis on achieving social goals rather than transferring discrete skills and capacities to pupils. Focusing on the years 1938-43, this paper outlines the rehabilitation efforts at Terence Bay, describes the programs the Sisters implemented, and evaluates the definitions of success ascribed to their training school just a few years later.

  4. Chemotaxonomy for naturally macerated tree-fern cuticles (Medullosales and Marattiales), Carboniferous Sydney and Mabou Sub-Basins, Nova Scotia, Canada

    Energy Technology Data Exchange (ETDEWEB)

    Zodrow, Erwin L. [Department of Earth Sciences, University College of Cape Breton, PO Box 5300, Nova Scotia, B1P 6L2 Sydney (Canada); Mastalerz, Maria [Indiana Geological Survey, Indiana University, 611 North Walnut Grove, 47405-2208 Bloomington, IN (United States)

    2001-07-01

    Naturally macerated cuticles (NMC) and one synangium, representing medullosalean and marattialean tree-fern species, from two Carboniferous coalfields in Nova Scotia, Canada, are investigated. The samples were analyzed by infrared spectroscopy (FTIR), and by pyrolysis-gas chromatograph/mass spectrometry (py-Gc/Ms) techniques in search for chemical signatures that would help in developing a chemotaxonomic classification of Carboniferous fern species, assuming genetically dependent make-up of cuticles. FTIR-derived CH{sub 2}/CH{sub 3} ratios, in conjunction with contributions from carboxyl groups, demonstrated a better potential for discriminating between medullosalean genera and species than molecular signatures obtained by py-Gc/Ms. However, the latter provided better data for differentiating medullosalean from marattialean tree ferns as a group. Changes in the chemical make-up of naturally macerated cuticles due to sample preparation are discussed.

  5. Outcomes of intraventricular hemorrhage and posthemorrhagic hydrocephalus in a population-based cohort of very preterm infants born to residents of Nova Scotia from 1993 to 2010.

    Science.gov (United States)

    Radic, Julia A E; Vincer, Michael; McNeely, P Daniel

    2015-06-01

    OBJECT Intraventicular hemorrhage (IVH) is a common complication of preterm birth, and the prognosis of IVH is incompletely characterized. The objective of this study was to describe the outcomes of IVH in a population-based cohort with minimal selection bias. METHODS All very preterm (≥ 30 completed weeks) patients born in the province of Nova Scotia were included in a comprehensive database. This database was screened for infants born to residents of Nova Scotia from January 1, 1993, to December 31, 2010. Among very preterm infants successfully resuscitated at birth, the numbers of infants who died, were disabled, developed cerebral palsy, developed hydrocephalus, were blind, were deaf, or had cognitive/language scores assessed were analyzed by IVH grade. The relative risk of each outcome was calculated (relative to the risk for infants without IVH). RESULTS Grades 2, 3, and 4 IVH were significantly associated with an increased overall mortality, primarily in the neonatal period, and the risk increased with increasing grade of IVH. Grade 4 IVH was significantly associated with an increased risk of disability (RR 2.00, p < 0.001), and the disability appeared to be primarily due to cerebral palsy (RR 6.07, p < 0.001) and cognitive impairment (difference in mean MDI scores between Grade 4 IVH and no IVH: -19.7, p < 0.001). No infants with Grade 1 or 2 IVH developed hydrocephalus, and hydrocephalus and CSF shunting were not associated with poorer outcomes when controlling for IVH grade. CONCLUSIONS Grades 1 and 2 IVH have much better outcomes than Grades 3 or 4, including a 0% risk of hydrocephalus in the Grade 1 and 2 IVH cohort. Given the low risk of selection bias, the results of this study may be helpful in discussing prognosis with families of very preterm infants diagnosed with IVH.

  6. Crude costs: a framework for a full-cost accounting analysis of oil and gas exploration off Cape Breton, Nova Scotia

    International Nuclear Information System (INIS)

    Landon, L.; Pannozzo, L.

    2001-12-01

    Defined as the total quantity of all goods and services produced and the total money earned and spent, the Gross Domestic Product (GDP) is a measure used to determine how well an economy is doing. For its part, the Genuine Progress Index (GPI) measures 26 variables and was first developed in 1995. In Nova Scotia, a set of 20 social, economic and environmental indicators are examined to obtain a better picture of the well-being of the region and determine if the development is sustainable over time. The authors explained their approach based on the use of GPI analysis to assist decision makers in identifying the real costs and benefits of different options applied to the oil and gas exploration situation off Cape Breton, Nova Scotia. The document is divided into five parts as follows: (1) Part 1: introduction, (2) Part 2: natural capital and the impacts of oil and gas development, (3) Part 3: social capital and the economic value of fishing and tourism, (4) Part 4: the real cost of oil and gas, and (5) Part 5: recommendations. Some of the recommendations call for the further study of cumulative and sub-lethal effects from petroleum development, the establishment of Marine Protected Areas preceded by a moratorium on oil and gas exploration in the Southern Gulf of St. Lawrence and Sydney Bight areas until the establishment of the Areas is made, and that future environmental assessments concerning oil and gas development to address the impacts on species and ecosystems as a whole. 209 refs., 11 tabs., 4 figs

  7. Geometry and structure of the pull-apart basins developed along the western South American-Scotia plate boundary (SW Atlantic Ocean)

    Science.gov (United States)

    Esteban, F. D.; Tassone, A.; Isola, J. I.; Lodolo, E.; Menichetti, M.

    2018-04-01

    The South American-Scotia plate boundary is a left-lateral fault system which runs roughly E-W for more than 3000 km across the SW Atlantic Ocean and the Tierra del Fuego Island, reaching to the west the southern Chile Trench. Analyses of a large dataset of single- and multi-channel seismic reflection profiles acquired offshore has allowed to map the trace of the plate boundary from Tierra del Fuego to the Malvinas Trough, a tectonic depression located in the eastern part of the fault system, and to reconstruct the shape and geometry of the basins formed along the principal displacement zone of the fault system. Three main Neogene pull-apart basins that range from 70 to 100 km in length, and from 12 to 22 km in width, have been identified along this segment of the plate boundary. These basins have elongated shapes with their major axes parallel to the ENE-WSW direction of the fault zone. The sedimentary architecture and the infill geometry of the basins suggest that they represent mostly strike-slip dominated transtension basins which propagated from E to W. The basins imaged by seismic data show in some cases geometrical and structural features linked to the possible reactivation of previous wedge-top basins and inherited structures pertaining to the external front of the Magallanes fold-and-thrust compression belt, along which the South American-Scotia fault system has been superimposed. It is suggested that the sequence of the elongated basins occur symmetrically to a thorough going strike-slip fault, in a left-stepping geometrical arrangement, in a manner similar to those basins seen in other transcurrent environments.

  8. An economic evaluation of forest improvement opportunities and impacts from the emergence of a biomass fuel market in southwestern Nova Scotia

    International Nuclear Information System (INIS)

    Manley, A.L.; Savage, G.D.

    1993-01-01

    In 1991, Nova Scotia's public power utility initiated a process to purchase privately produced electrical power. A proposal was received to produce 20--25 megawatts from the burning of 350 to 400,000 tonnes annually of wood residue and forest biomass in a co-generation facility in southwestern Nova Scotia, Canada. This proposal has been proceeding and is nearing the construction phase. As a result of this potential market, there is an opportunity for increasing the scope and extent of forest improvement operations. Options for a closer integration of planning, harvesting, and silviculture activities will emerge. Optimum end use allocation could occur and enhance overall economic efficiency. The objective of this project is to assess the effect that this emerging market for forest biomass could have on forest management in the supply area. This project has two phases. Phase 1, presented here, develops the framework and methodology. Phase 2 will apply a linear programming-based analytical model for evaluation. Phase 1 accumulated the required data and information for both the current management and marketing situation and that including the emerging biomass market. Growth and yield of the natural stand types were calculated for a mixture of conventional roundwood products and chip equivalents. Management regimes, based on current forest type, site class, and appropriate silviculture treatments, were established. Expected multiproduct yields, by regime were estimated. Silviculture and harvest costs along with product revenues were used to calculate standing timber and soil expectation values. In Phase 2, a stand-based optimization model will be developed to explore and evaluate the long term opportunities and differences between the present and emerging management and market situations

  9. A new watershed assessment framework for Nova Scotia: A high-level, integrated approach for regions without a dense network of monitoring stations

    Science.gov (United States)

    Sterling, Shannon M.; Garroway, Kevin; Guan, Yue; Ambrose, Sarah M.; Horne, Peter; Kennedy, Gavin W.

    2014-11-01

    High-level, integrated watershed assessments are a basic requirement for freshwater planning, as they create regional summaries of multiple environmental stressors for the prioritization of watershed conservation, restoration, monitoring, and mitigation. There is a heightened need for a high-level, integrated watershed assessment in Nova Scotia as it faces pressing watershed issues relating to acidification, soil erosion, acid rock drainage, eutrophication, and water withdrawals related to potential shale gas development. But because of the relative sparseness of the on-the-ground effects-based data, for example on water quality or fish assemblages, previously created approaches for integrated watershed assessment cannot be used. In a government/university collaboration, we developed a new approach that relies solely on easier-to-collect and more available exposure-based variables to perform the first high-level watershed assessment in Nova Scotia. In this assessment, a total of 295 watershed units were studied. We used Geographic Information Systems (GIS) to map and analyze 13 stressor variables that represent risks to aquatic environment (e.g., road/stream crossing density, acid rock drainage risk, surface water withdrawals, human land use, and dam density). We developed a model to link stressors with impacts to aquatic systems to serve as a basis for a watershed threat ranking system. Resource management activities performed by government and other stakeholders were also included in this analysis. Our assessment identifies the most threatened watersheds, enables informed comparisons among watersheds, and indicates where to focus resource management and monitoring efforts. Stakeholder communication tools produced by the NSWAP include a watershed atlas to communicate the assessment results to a broader audience, including policy makers and public stakeholders. This new framework for high-level watershed assessments provides a resource for other regions that also

  10. Late Neoproterozoic to Carboniferous genesis of A-type magmas in Avalonia of northern Nova Scotia: repeated partial melting of anhydrous lower crust in contrasting tectonic environments

    Science.gov (United States)

    Murphy, J. Brendan; Shellnutt, J. Gregory; Collins, William J.

    2018-03-01

    Avalonian rocks in northern mainland Nova Scotia are characterized by voluminous 640-600 Ma calc-alkalic to tholeiitic mafic to felsic magmas produced in a volcanic arc. However, after the cessation of arc activity, repeated episodes of felsic magmatism between ca. 580 Ma and 350 Ma are dominated by A-type geochemical characteristics. Sm-Nd isotopic data, combined with zircon saturation temperature estimates, indicate that these magmas were formed by high temperature (800-1050 °C) melting of the same anhydrous crustal source. Regional tectonic considerations indicate that A-type felsic magmatism was produced (1) at 580 Ma in a San Andreas-type strike slip setting, (2) at 495 Ma as Avalonia rifted off Gondwana, (3) at 465 and 455 in an ensialic island arc environment and (4) at 360-350 Ma during post-collisional, intra-continental strike-slip activity as Avalonia was translated dextrally along the Laurentian margin. These results attest to the importance of crustal source, rather than tectonic setting, in the generation of these A-type magmas and are an example of how additional insights are provided by comparing the geochemical and isotopic characteristics of igneous suites of different ages within the same terrane. They also suggest that the shallow crustal rocks in northern mainland Nova Scotia were not significantly detached from their lower crustal source between ca. 620 Ma and 350 Ma, a time interval that includes the separation of Avalonia from Gondwana, its drift and accretion to Laurentia as well as post-accretionary strike-slip displacement.

  11. Sable Offshore Energy Inc.: Response to 'The Canada-Nova Scotia Offshore Petroleum Board Benefits Plan Decision Report' Condition No. 3: Employment and Training Plan; Condition No. 4: Research and Development Plan; Condition No. 6: Disadvantaged Individual or Groups; Condition No. 7: Technology Transfer

    International Nuclear Information System (INIS)

    1998-01-01

    Decisions of the Canada-Nova Scotia Offshore Petroleum Board, regarding the responses of Sable Offshore Energy Inc (SOEI) to conditions imposed by the Board in the Sable Offshore Energy Project Canada-Nova Scotia Benefit Plan Decision Report, have been announced. According to the press release (copy attached), the Board accepted the responses of SOEI regarding the establishment and staffing of an office in Nova Scotia for the implementation and project management and training of project personnel, the level of expenditures for research and development to be undertaken in Nova Scotia, proposed initiatives for employment and training opportunities for disadvantaged individuals and groups, and a technology transfer plan that will facilitate succession planning and create joint venturing opportunities for Nova Scotian and Canadian industry. tabs., figs

  12. Biological dataset collected from bottle casts from the R/V LAURENCE M. GOULD and the R/V NATHANIEL B. PALMER in the Southern Drake Passage and Scotia Sea in support of National Science Foundation projects OPP 03-30443 and ANT 04-44134 from 15 February 2004 to 09 August 2006 (NODC Accession 0049902)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Ocean biology data were collected in Southern Drake Passage and Scotia Sea during two research cruises supported by NSF awards. These two cruises, namely LMG0402 and...

  13. Visual record of intertidal disturbance caused by drift ice in the spring on the Atlantic coast of Nova Scotia [v1; ref status: indexed, http://f1000r.es/3fb

    Directory of Open Access Journals (Sweden)

    Willy Petzold

    2014-05-01

    Full Text Available In the early spring of 2014, an unusually large amount of sea ice drifted from the Gulf of St. Lawrence, where it had been produced, towards the open Atlantic Ocean through the Cabot Strait, between Nova Scotia and Newfoundland, Canada. In early April, significant amounts of drift ice reached the Atlantic coast of mainland Nova Scotia. The ice floes persisted in those coastal waters for up to 16 days, depending on the location. During that time, the ice fragments caused extensive physical disturbance in rocky intertidal communities, removing high quantities of seaweeds and invertebrates. For example, at a location where the ice stayed for 9 days, the loss of macroalgal and invertebrate biomass was almost total. At a location where the ice stayed for 4 days, losses were lower, albeit still high overall. Such a magnitude of disturbance is not common on this coast, as sea ice had not reached the surveyed locations in the previous 4–5 years. We suggest that the frequency of ice scour events may help to predict intertidal community structure. This notion could be tested through multiannual surveys of ice conditions and biological communities along the Atlantic coast of Nova Scotia.

  14. Rapid climate oscillations in the Scotia Sea and results of the calving history of Antarctica during the last 200 000 years; Kurzfristige Klimaschwankungen im Scotiameer und Ergebnisse zur Kalbungsgeschichte der Antarktis waehrend der letzten 200 000 Jahre

    Energy Technology Data Exchange (ETDEWEB)

    Hofmann, A. [Bundesanstalt fuer Geowissenschaften und Rohstoffe, Hannover (Germany)

    1999-07-01

    Sedimentological and physical properties of five sediment cores have been analysed in order to reconstruct sedimentary processes during the late Quaternary in the southern Scotia Sea. The sediment cores have been dated by comparing magnetic susceptibility data of sediment cores with high-resolution dust records from the GRIP and Vostok ice cores. The data strongly suggest the occurrence of rapid climate oscillations, the so-called Dansgaard-Oeschger Cycles in the working area. Also, calving events of the Antarctic ice sheet similar to the Heinrich-events, known from the nothern hemisphere, could be detected in the sediment cores from the Scotia Sea. Under the assumption that magnetic susceptibility is a dust signal, two age models were established for each sediment core, one by correlation with the Vostok ice core, the other by correlation with the GRIP ice core. The prove rapid climate oscillations in the Scotia Sea magnetic susceptibility was measured in high resolution. The high resolution magnetic susceptibility of the sediment cores shows similar variations as the calcium signal of the GRIP ice core. (orig.)

  15. Ten years of breast screening in the Nova Scotia breast screening program, 1991-2001. Experience: Use of an adaptable stereotactic device in the diagnosis of screening-detected abnormalities

    International Nuclear Information System (INIS)

    Caines, J.S.; Schaller, G.H.; Iles, S.E.; Woods, E.R.; Barnes, P.J.; Johnson, A.J.; Jones, G.R.M.; Borgaonkar, J.N.; Rowe, J.A.; Topp, T.J.; Porter, G.A.

    2005-01-01

    To evaluate and present 10-year outcomes of The Nova Scotia Breast Screening Program (NSBSP), a population-based screening program in Its province of Nova Scotia, Canada, total population 900 000. Organized Breast Screening Program in Nova Scotia, Canada. Rates of participation, abnormal referrals, cancer detection rates, and benign: malignant (B:M) rates for core biopsy and surgical biopsy were calculated for asymptomatic women receiving a mammogram through The NSBSP 1991-2001. Of 192,454 mammograms performed on 71,317 women, 33% were aged 40 to 49 years, 39% aged 50 to 59 years, 23% aged 60 to 69 years, and 5% aged 70 years and over. Cancer detection rate increased in each age group respectively: 3.7, 5.8, 9.7, and 13.5 per 1000 population on first-time screens. The positive predictive value of an abnormal screen increased with increasing age groups. Benign breast surgery decreased with increased use of needle core breast biopsy (NCBB). Open surge decreased from 25 to 6 surgeries per 1000 screens. Of 1519 open surgical procedures (1328 women), 878 cancers were removed, with 37% 10mm or less, and 61% 15mm or less. In 613 women in whom the node status was assessed, 79% were negative. A quality screening program incorporating NCBB in the diagnostic work-up is effective in the early detection of breast cancer and results in less open surgery, particularly in younger women. (author)

  16. A Knowledge Transfer Study of the Utility of the Nova Scotia Seniors’ Mental Health Network in Implementing Seniors’ Mental Health National Guidelines

    Science.gov (United States)

    Bosma, Mark; Cassidy, Keri-Leigh; Le Clair, J Kenneth; Helsdingen, Sherri; Devichand, Pratima

    2011-01-01

    Background The Canadian Coalition for Seniors’ Mental Health (CCSMH) developed national best-practice guidelines in seniors’ mental health. Promoting adoption of new guidelines is challenging, as paper dissemination alone has limited impact on practice change. Purpose We hypothesized that the existing knowledge transfer (KT) mechanisms of the Nova Scotia Seniors’ Mental Health Network would prove useful in transferring the CCSMH best-practice guidelines. Methods In this observational KT study, CCSMH best-practice guidelines were delivered through two interactive, case-based teaching modules on Depression & Suicide, and Delirium via a provincial tele-education program and local face-to-face sessions. Usefulness of KT was measured using self-report evaluations of material quality and learning. Evaluation results from the two session topics and from tele-education versus face-to-face sessions were compared. Results Sessions were well attended (N = 347), with a high evaluation return rate (287, 83%). Most participants reported enhanced knowledge in seniors’ mental health and intended to apply knowledge to practice. Ratings did not differ significantly between KT session topics or modes of delivery. Conclusions The KT mechanisms of a provincial seniors’ mental health network facilitated knowledge acquisition and the intention of using national guidelines on seniors’ mental health among Nova Scotian clinicians. Key elements of accelerating KT used in this initiative are discussed. PMID:23251305

  17. Pollination, seed set and fruit quality in apple: studies with Osmia lignaria (Hymenoptera: Megachilidae in the Annapolis Valley, Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Cory Silas Sheffield

    2014-02-01

    Full Text Available The orchard crop pollinator Osmia lignaria (Hymenoptera: Megachilidae was evaluated for apple pollination in the Annapolis Valley, Nova Scotia, Canada during 2000-2001. Resulting pollination levels (measured as pollen grains on floral stigmas, percent fruit set, mature fruit weight and seed yield were evaluated against an attempted gradient of Osmia bee density. In addition, fruit quality was assessed using two symmetry indices, one based on fruit diameter, the second on fruit height. Pollination levels, percent fruit set and mature fruit quality were much higher than minimums required for adequate crop production, and all but pollination levels showed weak but significant decreases at increased distance from the established nests, suggesting that even at low numbers these bees may have been making significant contributions to apple production. Fruit were typically of better quality in areas of the orchard adjacent to Osmia nests, having fewer empty carpels and greater symmetry; fruit quality (i.e., symmetry is typically most reduced when two or more adjacent carpels are empty. Empty carpels reduce growth in fruit height rather than diameter, suggesting that symmetry indices using fruit diameter are not sensitive enough to evaluate fruit quality. Evidencing this, fruit without mature seeds observed in this study showed high symmetry based on diameter, but were greatly asymmetric with respect to fruit height. Further discussion on Osmia bees as apple pollinators and on methods of evaluating apple fruit quality with respect to seed distribution within the apple fruit are provided.

  18. An imputation/copula-based stochastic individual tree growth model for mixed species Acadian forests: a case study using the Nova Scotia permanent sample plot network

    Directory of Open Access Journals (Sweden)

    John A. KershawJr

    2017-09-01

    Full Text Available Background A novel approach to modelling individual tree growth dynamics is proposed. The approach combines multiple imputation and copula sampling to produce a stochastic individual tree growth and yield projection system. Methods The Nova Scotia, Canada permanent sample plot network is used as a case study to develop and test the modelling approach. Predictions from this model are compared to predictions from the Acadian variant of the Forest Vegetation Simulator, a widely used statistical individual tree growth and yield model. Results Diameter and height growth rates were predicted with error rates consistent with those produced using statistical models. Mortality and ingrowth error rates were higher than those observed for diameter and height, but also were within the bounds produced by traditional approaches for predicting these rates. Ingrowth species composition was very poorly predicted. The model was capable of reproducing a wide range of stand dynamic trajectories and in some cases reproduced trajectories that the statistical model was incapable of reproducing. Conclusions The model has potential to be used as a benchmarking tool for evaluating statistical and process models and may provide a mechanism to separate signal from noise and improve our ability to analyze and learn from large regional datasets that often have underlying flaws in sample design.

  19. Metabarcoding-based fungal diversity on coarse and fine particulate organic matter in a first-order stream in Nova Scotia, Canada [version 2; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Christian Wurzbacher

    2016-02-01

    Full Text Available Most streams receive substantial inputs of allochthonous organic material in the form of leaves and twigs (CPOM, coarse particulate organic matter. Mechanical and biological processing converts this into fine particulate organic matter (FPOM. Other sources of particles include flocculated dissolved matter and soil particles. Fungi are known to play a role in the CPOM conversion process, but the taxonomic affiliations of these fungi remain poorly studied. The present study seeks to shed light on the composition of fungal communities on FPOM and CPOM as assessed in a natural stream in Nova Scotia, Canada. Maple leaves were exposed in a stream for four weeks and their fungal community evaluated through pyrosequencing. Over the same period, four FPOM size fractions were collected by filtration and assessed. Particles had much lower ergosterol contents than leaves, suggesting major differences in the extent of fungal colonization. Pyrosequencing documented a total of 821 fungal operational taxonomic units (OTU, of which 726 were exclusive to particles and 47 to leaf samples. Most fungal phyla were represented, including yeast lineages (e.g., Taphrinaceae and Saccharomycotina, Basidiomycota, Chytridiomycota and Cryptomycota, but several classes of Pezizomycontina (Ascomycota dominated. Cluster dendrograms clearly separated fungal communities from leaves and from particles. Characterizing fungal communities may shed some light on the processing pathways of fine particles in streams and broadens our view of the phylogenetic composition of fungi in freshwater ecosystems.

  20. Identifiation of Phymatolithon lamii (Me. Lemoine Y.M. Chamberlain 1991 following bleaching in the upper intertidal zone of the Minas Basin, Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Brady Keith Quinn

    2016-03-01

    Full Text Available Objective: To identify an unusual encrusting calcareous organism found growing on upper intertidal rocks along the coast of the Minas Basin, Nova Scotia, Canada, which was thought to potentially represent a new, perhaps invasive species to the area. Methods: Observations were made of the organism growing in situ and of intact and dissected specimens under microscopes in the laboratory. Taxonomic keys were used to determine probable identity of the organism as a tunicate, sponge, bryozoan, marine lichen, or coralline red alga. These keys were then further used to identify samples to species. Results: The organism was determined to be Phymatolithon lamii (Me. Lemoine Y.M. Chamberlain 1991, an encrusting coralline red alga native to the study region. This species normally occurs in the subtidal zone, so its occurrence in the high intertidal zone was unusual and resulted in the alga becoming bleached and taking on an unusual appearance. Conclusions: The sample did not represent a new or invasive species to the study area. However, occurrence of this species on the high intertidal zone was novel and may have resulted from unusual climatic and/or oceanographic conditions in the study area in 2015 that allowed this alga to settle and grow in the intertidal zone for a time before death and bleaching occurred. Events such as this resulting from climate change may negatively impact recruitment to populations of coastal marine species and should be investigated further.

  1. Geology and climatic indicators in the Westphalian A New Glasgow formation, Nova Scotia, Canada: implications for the genesis of coal and of sandstone-hosted lead deposits

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, F.W. [Geological Survey of Canada, Ottawa, ON (Canada)

    1998-03-01

    Disagreement exists on whether the early Pennsylvanian climate of the Euramerican coal province was everwet or seasonal. Abundant paleopedological evidence, including calcrete-bearing vertisols, shows that during formation of Westphalian C to Stephanian coals in Nova Scotia, the climate was tropical and seasonal with a pronounced by dry season; but interpretation of Westphalian A-B coal-bearing sequences lacks this form of evidence. Development of calcrete-bearing vertisols in alluvial fan deposits of the Westphalian A New Glasgow formation indicate that a tropical climate with a pronounced dry season was already in force by early Westphalian time. During the dry season, the coal swamps of the early Westphalian Joggins and Springhill Mines formations were fed by groundwater from coeval alluvial fan deposits of the Polly Brook Formation at the basin margin. Sedimentological evidence indicates that, similarly, groundwater flowed northward from the toe of the New Glasgow alluvial fan, but correlative palustrine sediments have not been found on land in the New Glasgow area. The possibility remains of an early Westphalian coalfield associated with the New Glasgow formation to the north under the Northumberland Strait and Gulf of St. Lawrence. Formation of the Yava sandstone-hosted lead deposit in the fluvial Silver Mine Formation of Cape Breton Island, a stratigraphic equivalent of the Cumberland Basin coal swamps, indicates that such deposits can form in fluvial strata deposited under a tropical seasonal climate with a pronounced dry season.

  2. Impact of single versus multiple policy options on the economic feasibility of biogas energy production: Swine and dairy operations in Nova Scotia

    International Nuclear Information System (INIS)

    Brown, Bettina B.; Yiridoe, Emmanuel K.; Gordon, Robert

    2007-01-01

    The economic feasibility of on-farm biogas energy production was investigated for swine and dairy operations under Nova Scotia, Canada farming conditions, using net present value (NPV), internal rate of return (IRR), and payback period (PP) economic decision criteria. In addition, the effects of selected environmental and 'green' energy policy schemes on co-generation of on-farm biogas energy production and other co-benefits from anaerobic digestion of livestock manure were investigated. Cost-efficiencies arising from economies of scale for on-farm anaerobic biogas production were found for swine farms, and less so for dairy production systems. Without incentive schemes, on-farm biogas energy production was not economically feasible across the farm size ranges studied, except for 600- and 800-sow operations. Among single policy schemes investigated, green energy credit policy schemes generated the highest financial returns, compared to cost-share and low-interest loan schemes. Combinations of multiple policies that included cost-share and green energy credit incentive schemes generated the most improvement in financial feasibility of on-farm biogas energy production, for both swine and dairy operations

  3. Estimating the risk of bladder and kidney cancer from exposure to low-levels of arsenic in drinking water, Nova Scotia, Canada.

    Science.gov (United States)

    Saint-Jacques, Nathalie; Brown, Patrick; Nauta, Laura; Boxall, James; Parker, Louise; Dummer, Trevor J B

    2018-01-01

    Arsenic in drinking water impacts health. Highest levels of arsenic have been historically observed in Taiwan and Bangladesh but the contaminant has been affecting the health of people globally. Strong associations have been confirmed between exposure to high-levels of arsenic in drinking water and a wide range of diseases, including cancer. However, at lower levels of exposure, especially near the current World Health Organization regulatory limit (10μg/L), this association is inconsistent as the effects are mostly extrapolated from high exposure studies. This ecological study used Bayesian inference to model the relative risk of bladder and kidney cancer at these lower concentrations-0-2μg/L; 2-5μg/L and; ≥5μg/L of arsenic-in 864 bladder and 525 kidney cancers diagnosed in the study area, Nova Scotia, Canada between 1998 and 2010. The model included proxy measures of lifestyle (e.g. smoking) and accounted for spatial dependencies. Overall, bladder cancer risk was 16% (2-5μg/L) and 18% (≥5μg/L) greater than that of the referent group (water arsenic-levels within the current the World Health Organization maximum acceptable concentration. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Associations between family dinner frequency and specific food behaviors among grade six, seven, and eight students from Ontario and Nova Scotia.

    Science.gov (United States)

    Woodruff, Sarah J; Hanning, Rhona M

    2009-05-01

    Family dinner frequency has recently been associated in the literature with improved dietary profiles and healthy body weight in children and adolescents. However, it is not known whether family dinners are associated with other commonly reported food behaviors (fast food and soft drink consumption, breakfast skipping, and dieting) and attitudes (body weight concerns and self-efficacy for healthy eating) among Canadian students in grades 6, 7, and 8. A total of 3223 participants from Northern Ontario (Porcupine Region), Southern Ontario (Peel Region, Region of Waterloo, Toronto District), and Nova Scotia completed the Food Behavior Questionnaire during the 2005-2006 academic school year. Ordinal logistic regression analyses were used to determine the associations between family dinner frequency and food behaviors and attitudes. Higher family dinner frequency was significantly associated with less soft drink consumption, consuming breakfast on the day of the survey, the absence of a high body weight concern, having higher self-efficacy for healthy eating when at home with family, and during social times with friends. Researchers and clinicians should be aware of these associations when planning family based healthy eating strategies.

  5. Application of the principles of evidence-based practice in decision making among senior management in Nova Scotia's addiction services agencies.

    Science.gov (United States)

    Murphy, Matthew; MacCarthy, M Jayne; McAllister, Lynda; Gilbert, Robert

    2014-12-05

    Competency profiles for occupational clusters within Canada's substance abuse workforce (SAW) define the need for skill and knowledge in evidence-based practice (EBP) across all its members. Members of the Senior Management occupational cluster hold ultimate responsibility for decisions made within addiction services agencies and therefore must possess the highest level of proficiency in EBP. The objective of this study was to assess the knowledge of the principles of EBP, and use of the components of the evidence-based decision making (EBDM) process in members of this occupational cluster from selected addiction services agencies in Nova Scotia. A convenience sampling method was used to recruit participants from addiction services agencies. Semi-structured qualitative interviews were conducted with eighteen Senior Management. The interviews were audio-recorded, transcribed verbatim and checked by the participants. Interview transcripts were coded and analyzed for themes using content analysis and assisted by qualitative data analysis software (NVivo 9.0). Data analysis revealed four main themes: 1) Senior Management believe that addictions services agencies are evidence-based; 2) Consensus-based decision making is the norm; 3) Senior Management understand the principles of EBP and; 4) Senior Management do not themselves use all components of the EBDM process when making decisions, oftentimes delegating components of this process to decision support staff. Senior Management possess an understanding of the principles of EBP, however, when making decisions they often delegate components of the EBDM process to decision support staff. Decision support staff are not defined as an occupational cluster in Canada's SAW and have not been ascribed a competency profile. As such, there is no guarantee that this group possesses competency in EBDM. There is a need to advocate for the development of a defined occupational cluster and associated competency profile for this

  6. Weak feedbacks, governance mismatches, and the robustness of social-ecological systems: an analysis of the Southwest Nova Scotia lobster fishery with comparison to Maine

    Directory of Open Access Journals (Sweden)

    Allain J. . Barnett

    2014-12-01

    Full Text Available The insights in Governing the Commons have provided foundational ideas for commons research in the past 23 years. However, the cases that Elinor Ostrom analyzed have been exposed to new social, economic, and ecological disturbances. What has happened to these cases since the 1980s? We reevaluated one of Ostrom's case studies, the lobster and groundfishery of Port Lameron, Southwest Nova Scotia (SWNS. Ostrom suggested that the self-governance of this fishery was fragile because the government did not recognize the rights of resource users to organize their own rules. In the Maine lobster fishery, however, the government formalized customary rules and decentralized power to fishing ports. We applied the concepts of feedback, governance mismatches, and the robustness of social-ecological systems to understand the pathway of institutional change in Port Lameron. We revisited the case of Port Lameron using marine harvesters' accounts collected from participant observation, informal interviews and surveys, and literature on fisheries policy and ecology in SWNS and Maine. We found that the government's failure to recognize the customary rights of harvesters to organize has weakened feedback between the operational level, where resource users interact with the resource, and the collective-choice level, where agents develop rules to influence the behavior of resource users. This has precipitated governance mismatches, which have led harvesters to believe that the decision-making process is detrimental to their livelihoods. Thus, harvesters rarely participate in decision making and resist regulatory change. In Maine, harvesters can influence decisions through participation, but there is a trade-off. With higher influence in decisions, captains have co-opted the decision-making process. Nevertheless, we suggest that the fisheries of SWNS are more vulnerable to social-ecological change because of weaker feedbacks than in Maine. Finally, we have discussed

  7. Implementation of resources to support patient physical activity through diabetes centres in Nova Scotia: the effectiveness of enhanced support for exercise participation.

    Science.gov (United States)

    Fowles, Jonathon R; Shields, Chris; d'Entremont, Lisette; McQuaid, Stephanie; Barron, Brittany; Dunbar, Peggy

    2014-12-01

    The purpose of this study was to determine the effectiveness of enhancing support for physical activity counselling and exercise participation at diabetes centres in Nova Scotia on physical activity and exercise behaviours and clinical outcomes in patients with type 2 diabetes mellitus. In all, 180 patients at 8 diabetes centres participated in this observational study. A range of enhanced supports for exercise were offered at these centres. A kinesiologist was added to the diabetes care team to primarily provide extra physical activity counselling and exercise classes. Patient physical activity and exercise levels, efficacy perceptions and mean glycated hemoglobin (A1C) were evaluated at baseline and 6 months. We compared changes in these variables for patients who participated in the enhanced supports versus patients who did not. Participants who attended exercise classes (n=46), increased moderate physical activity by 27% and doubled resistance exercise participation (1.0±1.8 to 2.0±2.1 days per week) whereas those who did not attend exercise classes (n=49) reduced moderate physical activity by 26% and did not change resistance exercise participation (interactions, p=0.04 and p=0.07, respectively). Patients who received resistance band instruction (n=15) from a kinesiologist had reductions in A1C (from 7.5±1.4 to 7.1±1.2; p=0.04), whereas other subgroups did not have significant changes in A1C. Offering enhanced support for exercise at diabetes centres produced improvements in physical activity and exercise in type 2 diabetes patients. Resistance band instruction from a kinesiologist combined with participating in a walking and resistance training program improved glycemic control, which underscores the importance of including exercise professionals in diabetes management. Copyright © 2014 Canadian Diabetes Association. Published by Elsevier Inc. All rights reserved.

  8. Combined DC resistivity and induced polarization (DC-IP) for mapping the internal composition of a mine waste rock pile in Nova Scotia, Canada

    Science.gov (United States)

    Power, Christopher; Tsourlos, Panagiotis; Ramasamy, Murugan; Nivorlis, Aristeidis; Mkandawire, Martin

    2018-03-01

    Mine waste rock piles (WRPs) can contain sulfidic minerals whose interaction with oxygen and water can generate acid mine drainage (AMD). Thus, WRPs can be a long-term source of environmental pollution. Since the generation of AMD and its release into the environment is dependent on the net volume and bulk composition of waste rock, effective characterization of WRPs is necessary for successful remedial design and monitoring. In this study, a combined DC resistivity and induced polarization (DC-IP) approach was employed to characterize an AMD-generating WRP in the Sydney Coalfield, Nova Scotia, Canada. Two-dimensional (2D) DC-IP imaging with 6 survey lines was performed to capture the full WRP landform. 2D DC results indicated a highly heterogeneous and moderately conductive waste rock underlain by a resistive bedrock containing numerous fractures. 2D IP (chargeability) results identified several highly-chargeable regions within the waste, with normalized chargeability delineating regions specific to waste mineralogy only. Three-dimensional (3D) DC-IP imaging, using 17 parallel lines on the plateau of the pile, was then used to focus on the composition of the waste rock. The full 3D inverted DC-IP distributions were used to identify coincident and continuous zones (isosurfaces) of low resistivity (0.4 mS/m) that were inferred as generated AMD (leachate) and stored AMD (sulfides), respectively. Integrated geological, hydrogeological and geochemical data increased confidence in the geoelectrical interpretations. Knowledge on the location of potentially more reactive waste material is extremely valuable for improved long-term AMD monitoring at the WRP.

  9. Performance assessment of a single-layer moisture store-and-release cover system at a mine waste rock pile in a seasonally humid region (Nova Scotia, Canada).

    Science.gov (United States)

    Power, Christopher; Ramasamy, Murugan; Mkandawire, Martin

    2018-03-03

    Cover systems are commonly applied to mine waste rock piles (WRPs) to control acid mine drainage (AMD). Single-layer covers utilize the moisture "store-and-release" concept to first store and then release moisture back to the atmosphere via evapotranspiration. Although more commonly used in semi-arid and arid climates, store-and-release covers remain an attractive option in humid climates due to the low cost and relative simplicity of installation. However, knowledge of their performance in these climates is limited. The objective of this study was to assess the performance of moisture store-and-release covers at full-scale WRPs located in humid climates. This cover type was installed at a WRP in Nova Scotia, Canada, alongside state-of-the-art monitoring instrumentation. Field monitoring was conducted over 5 years to assess key components such as meteorological conditions, cover material water dynamics, net percolation, surface runoff, pore-gas, environmental receptor water quality, landform stability and vegetation. Water balances indicate small reductions in water influx to the waste rock (i.e., 34 to 28% of precipitation) with the diminished AMD release also apparent by small improvements in groundwater quality (increase in pH, decrease in sulfate/metals). Surface water quality analysis and field observations of vegetative/aquatic life demonstrate significant improvements in the surface water receptor. The WRP landform is stable and the vegetative cover is thriving. This study has shown that while a simple store-and-release cover may not be a highly effective barrier to water infiltration in humid climates, it can be used to (i) eliminate contaminated surface water runoff, (ii) minimize AMD impacts to surface water receptor(s), (iii) maintain a stable landform, and (iv) provide a sustainable vegetative canopy.

  10. Assessing the disturbance potential of small unoccupied aircraft systems (UAS on gray seals (Halichoerus grypus at breeding colonies in Nova Scotia, Canada

    Directory of Open Access Journals (Sweden)

    Lauren Arona

    2018-03-01

    Full Text Available The use of small unoccupied aircraft systems (UAS for ecological studies and wildlife population assessments is increasing. These methods can provide significant benefits in terms of costs and reductions in human risk, but little is known if UAS-based approaches cause disturbance of animals during operations. To address this knowledge gap, we conducted a series of UAS flights at gray seal breeding colonies on Hay and Saddle Islands in Nova Scotia, Canada. Using a small fixed-wing UAS, we assessed both immediate and short-term effects of surveys using sequential image analysis and between-flight seal counts in ten, 50 m2 random quadrats at each colony. Counts of adult gray seals and young-of-the-year animals between first and second flights revealed no changes in abundance in quadrats (matched pair t-test p > 0.69 and slopes approaching 1 for linear regression comparisons (r2 > 0.80. Sequential image analysis revealed no changes in orientation or posture of imaged animals. We also assessed the acoustic properties of the small UAS in relation to low ambient noise conditions using sound equivalent level (Leq measurements with a calibrated U-MIK 1 and a 1/3 octave band soundscape approach. The results of Leq measurements indicate that small fixed-wing UAS are quiet, with most energy above 160 Hz, and that levels across 1/3 octave bands do not greatly exceed ambient acoustic measurements in a quiet field during operations at standard survey altitudes. As such, this platform is unlikely to acoustically disturb gray seals at breeding colonies during population surveys. The results of the present study indicate that the effects of small fixed-wing UAS on gray seals at breeding colonies are negligible, and that fixed-wing UAS-based approaches should be considered amongst best practices for assessing gray seal colonies.

  11. Five-year performance monitoring of a high-density polyethylene (HDPE) cover system at a reclaimed mine waste rock pile in the Sydney Coalfield (Nova Scotia, Canada).

    Science.gov (United States)

    Power, Christopher; Ramasamy, Murugan; MacAskill, Devin; Shea, Joseph; MacPhee, Joseph; Mayich, David; Baechler, Fred; Mkandawire, Martin

    2017-12-01

    Cover systems are commonly placed over waste rock piles (WRPs) to limit atmospheric water and oxygen ingress and control the generation and release of acid mine drainage (AMD) to the receiving environment. Although covers containing geomembranes such as high-density polyethylene (HDPE) exhibit the attributes to be highly effective, there are few, if any, published studies monitoring their performance at full-scale WRPs. In 2011, a HDPE cover was installed over the Scotchtown Summit WRP in Nova Scotia, Canada, and extensive field performance monitoring was conducted over the next five years. A range of parameters within the atmosphere, cover, waste rock, groundwater and surface water, were monitored and integrated into a comprehensive hydrogeochemical conceptual model to assess (i) atmospheric ingress to the waste rock, (ii) waste rock acidity and depletion and (iii) evolution of groundwater and surface water quality. Results demonstrate that the cover is effective and meeting site closure objectives. Depletion in oxygen influx resulted in slower sulphide oxidation and AMD generation, while a significant reduction in water influx (i.e. 512 to 50 mm/year) resulted in diminished AMD release. Consistent improvements in groundwater quality (decrease in sulphate and metals; increase in pH) beneath and downgradient of the WRP were observed. Protection and/or significant improvement in surface water quality was evident in all surrounding watercourses due to the improved groundwater plume and elimination of contaminated runoff over previously exposed waste rock. A variably saturated flow and contaminant transport model is currently being developed to predict long-term cover system performance.

  12. Depressive symptoms are not associated with leukocyte telomere length: findings from the Nova Scotia Health Survey (NSHS95, a population-based study.

    Directory of Open Access Journals (Sweden)

    Jonathan A Shaffer

    Full Text Available Premature shortening of leukocyte telomere length has been proposed as a novel mechanism by which depression may confer increased risk of adverse cardiovascular events. Prior studies demonstrating associations of depression and depressive symptoms with shorter leukocyte telomere length were small, included selected psychiatric outpatients, were based on convenience samples, and/or adjusted for a limited number of possible confounding factors.We examined the associations of depressive symptoms, probable depressive disorder, and specific depressive symptom clusters, as assessed by the Center for Epidemiological Studies--Depression (CES-D scale, with leukocyte telomere length, measured by using a real-time PCR method, in 2,225 apparently healthy participants from the 1995 Nova Scotia Health Survey population-based study. The mean age was 48.2 ± 18.9 years; 49.9% of participants were female; and the mean CES-D score was 7.4 ± 7.9. The mean telomere length was 5,301 ± 587 base pairs. In an unadjusted model, depressive symptoms were significantly associated with longer leukocyte telomere length (B = 27.6 base pairs per standard deviation increase in CES-D, 95% confidence interval [CI] = 3.1-52.1, p = 0.027. This association was no longer significant after adjustment for age and sex (B = 9.5, 95% CI = -14.6-33.6, p = 0.44 or after further adjustment for body mass index, Framingham risk score and previous history of ischemic heart disease (all p's ≥ 0.37. Neither probable depressive disorder nor specific depressive symptom clusters were independently associated with leukocyte telomere length.Concurrent depressive symptoms were not associated with leukocyte telomere length in a large, representative, population-based study.

  13. Knowledge of, beliefs about, and perceived barriers to the use of the emergency contraception pill among women aged 18-51 in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Whelan AM

    2011-09-01

    Full Text Available Objectives: To investigate women in Nova Scotia (NS, Canada with respect to their knowledge of, beliefs about, and perceptions of barriers to accessing emergency contraception pills (ECP.Methods: A random digit dialing approach was used to survey a representative sample of NS women aged 18-51. Analyses described the knowledge, beliefs, and perceived barriers associated with ECP access among participants. Particular focus was given to differences between younger (age 18-31 and older (age 32-51 women.Results: The survey response rate of 49% achieved the desired sample size of 770. Overall, women in NS appeared to be poorly informed about ECP with regards to effectiveness, proper timing of administration, how it works, as well as how to access Plan B®. Younger women (age 18-31 were significantly more likely than older women (age 32-51 to know that ECP does not always prevent pregnancy (p<0.01, that it can be taken more than 12 hours after unprotected intercourse (p<0.01, and that it is available without a prescription in pharmacies (p<0.01. Thirty percent of women agreed that ECP will cause an abortion, with older women (p<0.01 being more likely than younger women to agree. Cost and lack of privacy in pharmacies were identified as potential barriers to access.Conclusions: Lack of knowledge and the perception that ECP causes an abortion may influence a woman’s ability to consider ECP as an option should she find herself at risk of an unplanned pregnancy. To address this, efforts should be made to educate women (including older women about ECP and its availability in pharmacies.

  14. Erosional and depositional contourite features at the transition between the western Scotia Sea and southern South Atlantic Ocean: links with regional water-mass circulation since the Middle Miocene

    Science.gov (United States)

    Pérez, Lara F.; Hernández-Molina, F. Javier; Esteban, Federico D.; Tassone, Alejandro; Piola, Alberto R.; Maldonado, Andrés; Preu, Benedict; Violante, Roberto A.; Lodolo, Emanuele

    2015-08-01

    The aim of the present study was to characterise the morpho-sedimentary features and main stratigraphic stacking pattern off the Tierra del Fuego continental margin, the north-western sector of the Scotia Sea abyssal plain (Yaghan Basin) and the Malvinas/Falkland depression, based on single- and multi-channel seismic profiles. Distinct contourite features were identified within the sedimentary record from the Middle Miocene onwards. Each major drift developed in a water depth range coincident with a particular water mass, contourite terraces on top of some of these drifts being associated with interfaces between water masses. Two major palaeoceanographic changes were identified. One took place in the Middle Miocene with the onset of Antarctic Intermediate Water flow and the enhancement of Circumpolar Deep Water (CDW) flow, coevally with the onset of Weddell Sea Deep Water flow in the Scotia Sea. Another palaeoceanographic change occurred on the abyssal plain of the Yaghan Basin in the Late Miocene as a consequence of the onset of Southeast Pacific Deep Water flow and its complex interaction with the lower branch of the CDW. Interestingly, these two periods of change in bottom currents are coincident with regional tectonic episodes, as well as climate and Antarctic ice sheet oscillations. The results convincingly demonstrate that the identification of contourite features on the present-day seafloor and within the sedimentary record is the key for decoding the circulation of water masses in the past. Nevertheless, further detailed studies, especially the recovery of drill cores, are necessary to establish a more robust chronology of the evolutionary stages at the transition between the western Scotia Sea and the southern South Atlantic Ocean.

  15. Proceedings of the 2003 Annual Meeting of the Canadian Mathematics Education Study Group = Actes de la Rencontre Annuelle 2003 du Groupe Canadien d'Etude en Didactique des Mathematiques (27th, Wolfville, Nova Scotia, Canada, May 30-June 3, 2003)

    Science.gov (United States)

    Simmt, Elaine, Ed.; Davis, Brent, Ed.

    2004-01-01

    This submission contains the Proceedings of the 2003 Annual Meeting of the Canadian Mathematics Education Study Group (CMESG), held at Acadia University in Wolfville, Nova Scotia. The CMESG is a group of mathematicians and mathematics educators who meet annually to discuss mathematics education issues at all levels of learning. The aims of the…

  16. Nova Scotia Environment Act: Report

    Energy Technology Data Exchange (ETDEWEB)

    1994-01-01

    In January 1993, a comprehensive review and consolidation of 13 statutes currently under the Department of the Environment's administration began to create a more rational, efficient, and user-friendly framework for environmental management; to fulfill outstanding commitments for regulatory reform; and to provide an opportunity for focused stakeholder consultations on substantive changes to the legislative framework. Draft legislation was released for public comment in November 1993. This report summarizes the public comments but also includes comments by the Public Consultation Committee. Issues addressed include administration, environmental education and research, environmental assessment process, approvals and certificates, release of substances, hazardous substances and pesticides, contaminated sites, waste management, water management, inspections and investigations, orders, appeals, civil remedies, penalties and prosecutions, and documentary evidence.

  17. A new long-term care facilities model in nova scotia, Canada: protocol for a mixed methods study of care by design.

    Science.gov (United States)

    Marshall, Emily Gard; Boudreau, Michelle Anne; Jensen, Jan L; Edgecombe, Nancy; Clarke, Barry; Burge, Frederick; Archibald, Greg; Taylor, Anthony; Andrew, Melissa K

    2013-11-29

    Prior to the implementation of a new model of care in long-term care facilities in the Capital District Health Authority, Halifax, Nova Scotia, residents entering long-term care were responsible for finding their own family physician. As a result, care was provided by many family physicians responsible for a few residents leading to care coordination and continuity challenges. In 2009, Capital District Health Authority (CDHA) implemented a new model of long-term care called "Care by Design" which includes: a dedicated family physician per floor, 24/7 on-call physician coverage, implementation of a standardized geriatric assessment tool, and an interdisciplinary team approach to care. In addition, a new Emergency Health Services program was implemented shortly after, in which specially trained paramedics dedicated to long-term care responses are able to address urgent care needs. These changes were implemented to improve primary and emergency care for vulnerable residents. Here we describe a comprehensive mixed methods research study designed to assess the impact of these programs on care delivery and resident outcomes. The results of this research will be important to guide primary care policy for long-term care. We aim to evaluate the impact of introducing a new model of a dedicated primary care physician and team approach to long-term care facilities in the CDHA using a mixed methods approach. As a mixed methods study, the quantitative and qualitative data findings will inform each other. Quantitatively we will measure a number of indicators of care in CDHA long-term care facilities pre and post-implementation of the new model. In the qualitative phase of the study we will explore the experience under the new model from the perspectives of stakeholders including family doctors, nurses, administration and staff as well as residents and family members. The proposed mixed method study seeks to evaluate and make policy recommendations related to primary care in long

  18. Decision NSUARB-NG-98: in the matter of the Gas Distribution Act and in the matter of franchise applications for the distribution of natural gas in the province of Nova Scotia

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-16

    A decision was rendered following a public hearing conducted by the Nova Scotia Utility and Review Board (the Board) over 49 hearing days between April 12, 1999 and July 29, 1999, in the matter of applications for franchises to construct and operate natural gas delivery systems in the province of Nova Scotia under the authority of various acts. Part One of the report consists of the Board's findings on the province-wide franchise applications. Each application was evaluated in the context of the statutory, regulatory and policy criteria established by the Act and GIC Regulations. The Board drew from these criteria upon which its decision was based. A brief summary of the evidence provided by each applicant in respect of each key factor is presented, followed by the Board's findings in respect of that factor. Part two deals with the applications by the municipalities and co-operatives. A brief summary of each proposal is set out along with the Board's findings. Part three consists of comments by the Board in respect of other issues, including the regulatory environment, single end user franchises and municipal fees. Part four contains a summary of the Board's findings and conclusions. An addendum contains six schedules. Pursuant to Section 8 of the Gas Distribution Act, the Board granted a full regulation class franchise for a period of 25 years to Sempra Atlantic Gas Inc., subject to the approval of the Governor in Council and subject to the conditions set forth in Schedule 'A' attached; all other applications denied.

  19. Concordance with a STOPP (Screening Tool of Older Persons' Potentially Inappropriate Prescriptions) Criterion in Nova Scotia, Canada: Benzodiazepine and Zoplicone Prescription Claims by Older Adults with Fall-related Hospitalizaions.

    Science.gov (United States)

    Hill-Taylor, B; Sketris, I S; Gardner, D M; Thompson, K

    2016-01-01

    Optimization of prescribing in older adults is needed. The STOPP criteria provide a systematic way of identifying potentially inappropriate prescribing in this population. Previous research indicates poor concordance between benzodiazepine prescribing and STOPP. To determine the extent and predictors of benzodiazepine and zopiclone (BZD-Z) pharmacy dispensations in older adults with a history of a recent fall, in concordance with STOPP. Prescription claims data from the Nova Scotia Seniors' Phamacare Program were linked with fall-related injury data from the CIHI Discharge Abstract Database. Adults aged ≥ 66 years making a claim for a BZD-Z in the 100 days prior to fall-related hospitalization were identified. Their BZD-Z claims in the 100 days following discharge were also identified. Descriptive statistics, trend tests and logistical regression modelling were performed to examine predictors for continued use of BZD-Z post-fall. Over 5 years, from a pool of 8,271 older adults discharged following a fall-related hospitalization, 1,789 (21.6%) had made a claim for a BZD-Z in the 100 days prior to admission. Of these, 82% were women. Younger age and female sex were predictors of continuing BZD-Z dispensations post-fall. In the 100 days following discharge, 74.2% (n=1327) made a claim for at least one BZD-Z. BZD-Z use continued in 74% of patients following discharge from a fall-related hospitalization, representing limited concordance with the STOPP criterion. Such hospitalizations and follow-up care present an opportunity to address an ongoing modifiable risk factor.

  20. NSWEP: The Nova Scotia Wind Energy Project

    International Nuclear Information System (INIS)

    Hughes, L.; Little, T. A.

    2000-01-01

    A two-phase project, intended to educate Nova Scotians about the potential of wind power to help reduce the province's greenhouse gas emissions, thereby fulfilling a vital role in Canada's effort to mitigate climate change effects, is described. First phase of the project involves gathering of wind data; the second the installation of a number of wind turbines throughout the province. The data gathering phase encompasses site selection, the actual data gathering for a period of about ten months, data analysis, and creation of a four or five module educational program, to be linked with intermediate high school science, mathematics, geography and social studies curriculum objectives to provide an interdisciplinary examination of these topics, and convey a sense of the complexity of the issues involved. The second phase of the project is intended to promote the possible use of wind energy in the province by installing a number of 25 kW wind turbines at selected sites throughout the province, followed by the gathering analysis of data relating to the amount of power produced by the turbines, calculating the efficiency of turbines and comparing data with the data gathered in previous years. The project is expected to last at least five years, exposing about 4000 high school students to hands-on involvement with issues of climate change and sustainable energy. Parents and the community will be exposed to these same issues indirectly, aided by the relative proximity of the weather stations to schools and the strategic location of the wind turbines. 4 refs

  1. Cadmium, copper and iron in the Scotia Sea, Weddell Sea and Weddell/Scotia Confluence (Antarctica)

    NARCIS (Netherlands)

    Nolting, R.F.; Baar, H.J.W. de; Bennekom, A.J. van; Masson, A.

    1991-01-01

    Until recently, little was known about trace metals in the Southern Ocean. Vertical profiles and surface water sections along 49°W exhibit Cd concentrations of 0.2–0.8 nM, increasing with depth, as for phosphate. A linear relationship between Cd and phosphate exists as in other oceans; however, the

  2. Students in Nova Scotia Schools Without Teacher-Librarians are not Achieving Department of Education Expectations for Information Literacy Skills. A review of: Gunn, Holly, and Gary Hepburn. “Seeking Information for School Purposes on the Internet.” Canadian Journal of Learning and Technology 29.1 (Winter 2003: 67‐88. 24 May 2007

    Directory of Open Access Journals (Sweden)

    Gayle Bogel

    2007-06-01

    Full Text Available Objective – This study investigated whether the expectations for Internet searching strategies outlined in provincial curriculumg oals are being met in Nova Scotia Schools. Twelfth-grade students in representative schools were surveyed as to their Internet information seeking strategies and their perceptions of the effectiveness of those strategies. The results are presented as six themes based on the survey questions.Design – Survey questionnaire consisting of yes/no, multiple-choice, Likert style, and open‐ended responses.Setting – Twelfth‐grade students from four high schools in one district in Nova Scotia. Total participants: 198.Subjects – Questionnaires were analyzed from 243 general practitioners, practice nurses, and practice managers in four Nottingham primary care trusts as well as practices in the Rotherham Health Authority area.Methods – Four research questions guided this study: 1. What strategies and techniques do students use that are helpful for information‐seeking on the Internet? 2. What knowledge do students have of the different World Wide Web search engines? 3. How do students perceive their ability to locate information for school purposes on the Internet? 4. How do students learn how to seek information on the Internet for school related assignments? The survey was developed through a literature review of previous research. Each survey item reflected a theme and one of the four research questions. The survey was field tested in a pilot study with two twelfth‐grade students, and two twelfth grade English classes.The sample was assembled by asking principals at the four schools to identify two classes in each of their schools that represented mixed academic abilities. Three schools chose English classes, and one school chose math classes participate in the study. All students had agreed to be a part of the study and only students present in class on the day the questionnaire was given were represented. No

  3. Nova Scotia Teachers' ADHD Knowledge, Beliefs, and Classroom Management Practices

    Science.gov (United States)

    Blotnicky-Gallant, Pamela; Martin, Cheron; McGonnell, Melissa; Corkum, Penny

    2015-01-01

    Attention-deficit/hyperactivity disorder (ADHD) has a significant impact on children's social, emotional, and academic performance in school, and as such, teachers are in a good position to provide evidence-based interventions to help ensure optimal adjustment of their students. The current study examined teachers' knowledge and beliefs about…

  4. Toxicity of road salt to Nova Scotia amphibians.

    Science.gov (United States)

    Collins, Sara J; Russell, Ronald W

    2009-01-01

    The deposition of chemical pollutants into roadside wetlands from runoff is a current environmental concern. In northern latitudes, a major pollutant in runoff water is salt (NaCl), used as de-icing agents. In this study, 26 roadside ponds were surveyed for amphibian species richness and chloride concentration. Acute toxicity tests (LC(50)) were performed on five locally common amphibian species using a range of environmentally significant NaCl concentrations. Field surveys indicated that spotted salamanders (Ambystoma maculatum) and wood frogs (Rana sylvatica) did not occupy high chloride ponds. American toads (Bufo americanus) showed no pond preference based on chloride concentration. Acute toxicity tests showed spotted salamanders and wood frogs were most sensitive to chloride, and American toads were the least. Spring peepers (Pseudacris crucifer) and green frogs (Rana clamitans) showed intermediate sensitivities. We concluded that chloride concentrations in ponds due to application of de-icing salts, influenced community structure by excluding salt intolerant species.

  5. Toxicity of road salt to Nova Scotia amphibians

    International Nuclear Information System (INIS)

    Collins, Sara J.; Russell, Ronald W.

    2009-01-01

    The deposition of chemical pollutants into roadside wetlands from runoff is a current environmental concern. In northern latitudes, a major pollutant in runoff water is salt (NaCl), used as de-icing agents. In this study, 26 roadside ponds were surveyed for amphibian species richness and chloride concentration. Acute toxicity tests (LC 50 ) were performed on five locally common amphibian species using a range of environmentally significant NaCl concentrations. Field surveys indicated that spotted salamanders (Ambystoma maculatum) and wood frogs (Rana sylvatica) did not occupy high chloride ponds. American toads (Bufo americanus) showed no pond preference based on chloride concentration. Acute toxicity tests showed spotted salamanders and wood frogs were most sensitive to chloride, and American toads were the least. Spring peepers (Pseudacris crucifer) and green frogs (Rana clamitans) showed intermediate sensitivities. We concluded that chloride concentrations in ponds due to application of de-icing salts, influenced community structure by excluding salt intolerant species. - Salt toxicity is presented as a mechanism affecting the distribution of amphibians and structure of amphibian communities in roadside wetlands

  6. Environmental illness in Nova Scotia, 1983-2003

    National Research Council Canada - National Science Library

    Janigan, David T

    2003-01-01

    ... 1989: Kitchen Investigations and Changes C. March-June 1989: Dishwasher Room Suspected Source of an Airborne Irritant D. October-December 1989: Further Dishwasher and Irritant (Sodium Hydroxide)...

  7. Annual report 1993-94 (Nova Scotia Resources Ltd., Halifax)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-31

    This Corporation is a provincial Crown corporation under the responsibility of the Minister of Mines and Energy. Established in 1981, the Corporation invests in and manages the Province`s participation in petroleum, energy and mineral resources development and related industrial projects. This annual report presents a description of the Cohasset project, offshore exploration, gas generating properties, natural gas, and finance. An auditor`s report and financial statements are included. A list of the Board of Directors, and principal officers is included.

  8. Educational Technology Program for Nova Scotia: Initial Phase. A Report on the Federal-Provincial Study of Educational Technology in Nova Scotia.

    Science.gov (United States)

    deVille, Barry, Ed.

    This is a preliminary examination of the present status and future prospects of educational technology in Nova Scotian schools. It is aimed at developing a plan to enhance the quality of educational technology by concentrating on systems which will be conducive to realizing educational goals at a reasonable cost. An overview of the institutional…

  9. Makahiki+WattDepot

    DEFF Research Database (Denmark)

    Johnson, Philip M.; Xu, Yongwen; Brewer, Robert S.

    2013-01-01

    to consumers. Since 2009, we have been designing, implementing, and evaluating an open source software "stack" to facilitate this research. This software stack consists of two custom systems called WattDepot and Makahiki, along with the open source components they rely upon (Java, Restlet, Postgres, Python...

  10. Octocorallia (Cnidaria: Anthozoa) from the Scotia Arc, South Atlantic Ocean. I. The genus Alcyonium Linnaeus, 1758

    NARCIS (Netherlands)

    Casas, C.; Ramil, F.; Ofwegen, van L.P.

    1997-01-01

    Three new species of Alcyonium collected by the Spanish Antarctic Expeditions "Antártida 8611" and "Bentart 95" are described and figured: Alcyonium paucilobulatum, A. grandis and A. southgeorgiensis. Another two species, A. antarcticum Wright & Studer, 1889, and Alcyonium sollasi Wright & Studer,

  11. Nitrous oxide emissions from forested and harvested ecosystems in northeastern Nova Scotia

    International Nuclear Information System (INIS)

    Kavanaugh, K.; Kellman, L.; Beltrami, H.

    2005-01-01

    Although studies have shown that deforestation alters the emissions of nitrous oxides (N 2 O) from forest soils in tropical environments, little is known about the northern temperate and boreal forests. This study monitored the N 2 O soil emissions from two 3 year old harvested and intact forest pairs of contrasting soil texture. The study was conducted through the late summer to early fall period in the Acadian forest of Atlantic Canada in order to quantify N 2 O emissions associated with each landuse type, and to determine the factors controlling these emissions. The suitability of a photoacoustic gas monitor (PGM) for in situ field measurements of this gas was also evaluated. Each site was equipped with 11 permanent collars for surface flux measurements designed to capture the microsite variability. Subsurface soil gas samplers were installed at depths of 0, 10, 20 and 35 cm below the organic-mineral soil interface. A nonsteady-state vented surface flux chamber coupled to the PGM was used to regularly measure the surface fluxes in order to quantify the soil-atmosphere N 2 O exchanges. The important zones of N 2 O production in the profile were identified by less frequent measurements of subsurface gas concentrations. Soil nitrogen, soil bulk density, and soil pH were measured at each site. Preliminary results reveal that spatial and temporal variability in surface emissions are very high and that there is a difference in the magnitude of fluxes between harvested and intact forest pairs

  12. Conservation of the Sinclair Inn Museum, and the Painted Room Annapolis Royal, Nova Scotia, Canada

    Science.gov (United States)

    Shaftel, A.; Ward, J.

    2017-08-01

    Conservation of the historic 18thC. Sinclair Inn Museum, and of the recently discovered late 18th/early 19thC. unique panoramic wall paintings located in an upstairs room, are co-dependent. This project was carried out with Canadian Conservation Institute (CCI) staff, and Conservator in Private Practice Ann Shaftel. This paper will introduce the Sinclair Inn Museum, outline the CCI murals and building investigations of 2011-15, the mural investigation of 2015-16, which confirmed that the mural extended to all four walls of the function room, now referred to as the Painted Room, and to describe how it has been revealed and conserved to date.

  13. Functional groups in a single pteridosperm species: Variability and circumscription (Pennsylvanian, Nova Scotia, Canada)

    Science.gov (United States)

    Zodrow, E.L.; Mastalerz, Maria

    2007-01-01

    Multiple foliar specimens of the Late Pennsylvanian fossil pteridosperm [gymnosperm] Alethopteris zeilleri (Ragot) Wagner were collected from one restricted stratigraphical horizon in the Canadian Sydney Coalfield. Variability of functional-group distribution using FTIR technique was studied in compressions, adaxial versus abaxial cuticles, and in unseparated cuticles as a function of maceration time from 48 to 168??h. The results obtained document spectral variability that could be expected within specimens of one species. For example, CH2/CH3 and Al/ox ratios can differ by as much as 20% of the values. Moreover, the experiments performed confirm that by using a previously established maceration protocol, long maceration periods do not bias FTIR spectra in terms of oxygenation overprinting. The inference that this cuticle is robust, under the given diagenetic level, probably reflects a reassuring degree of chemical fidelity of the Pennsylvanian plant to support Carboniferous chemotaxonomic observations. ?? 2006 Elsevier B.V. All rights reserved.

  14. Climate Change, Forests, and Water Supply: Managing to Reduce Vulnerability in Central Nova Scotia

    Science.gov (United States)

    Steenberg, J.; Duinker, P.

    2009-12-01

    Global climate change is increasingly relevant in managing Canada’s forests sustainably. Forest managers are faced with the necessity of incorporating climate change into forest management plans. The formulation and evaluation of potential management strategies to contend with expected impacts of climate change will be necessary to reduce forest sector vulnerability. The Halifax Regional Water Commission manages forest watersheds for the purpose of supplying clean water to much of the Halifax Regional Municipality. The purpose of this study is to characterize the future forest structure of the two principal watersheds supplying the Halifax Regional Municipality using simulation modelling and to develop a framework of adaptive forest management. A combination of uncertainty analysis, sensitivity analysis, and field data collection are used to refine, calibrate, and validate the spatially dynamic landscape disturbance model LANDIS-II prior to the incorporation of climate change scenarios into model simulations. Final model-based analysis will inform framework development dedicated to improving watershed resilience in the face of future climate change. This study is applicable to forest management under a changing climate, but also has further significance to water security, as watershed management and point-source protection are tightly linked to forest management.

  15. Controversy still simmers over plan to build plasma-fractionation plant in Nova Scotia.

    OpenAIRE

    Robb, N

    1995-01-01

    Controversy still simmers over a plan by the Canadian Red Cross Society and a US biopharmaceutical manufacturer to build a plasma-fractionation plant near Halifax. The unilateral decision to go ahead with the plant was taken as the Krever inquiry into Canada's blood-supply system was holding public hearings across the country. A panel created to evaluate the proposal has supported the fractionation plant, but made additional recommendations concerning product pricing, research and development...

  16. The Military in Disaster Relief After the Explosion in Halifax, Nova Scotia, December 1917

    Science.gov (United States)

    2017-06-09

    order and security before the meeting took place. The outsize influence of soldiers and sailors made both crowds and politicians feel safe .228 This...another important Canadian port, gave way to Halifax around December when the St. Lawrence River froze.7 As an important military port, Halifax...Militia in Halifax were ineligible for overseas duty. Age, family status, or minor disability restricted them to serving in their home country.10 The

  17. Summary of macrofloral biostratigraphy of Sydney Coalfield, Nova Scotia, Canada (Carboniferous, Westphalian/Cantabrian age)

    Energy Technology Data Exchange (ETDEWEB)

    Zodrow, E.L. (University College of Cape Breton, Sydney, NS (Canada). Dept. of Geology)

    1989-04-01

    Bell's (1938) macrofloral biostratigraphy (three floristic zones of Westphalian C and D ages) of the Sydney Coalfield is fundamentally revised. The revision is based mainly on two lines of evidence: newly collected macrofloras (sphenophylls, odontopterids, pecopterids) by the present author and K. McCandlish since 1974 from the upper part of the Sydney Coalfield in the Point Aconi area, and extension of ranges for some of Bell's records, especially {ital S. cuneifolium} and {ital Linopteris obliqua}. As interpretative results, the age of the Sydney Coalfield is considered to be Westphalian C to Cantabrian (earliest Stephanian), with the two recognized macrofloristic zones ({ital Lonchopteris eschweileriana} and {ital L. obliqua} zones) of Westphalian C, and Westphalian D and Cantabrian ages, respectively. 21 refs., 4 figs.

  18. Depot Maintenance: Executed Workload and Maintenance Operations at DOD Depots

    Science.gov (United States)

    2017-02-03

    in turn enable testing of helicopter rotor blades. The Army has also made investments in logistics software at all of its depots. According to the...maintenance and repair of structural helicopter airframes and blades; advanced composite technologies; flight controls and control surfaces; and...level maintenance on a wide range of vehicles and other military assets, including helicopters , combat vehicles, ships, aircraft, engines, and software

  19. Network technology for depot modernization

    Energy Technology Data Exchange (ETDEWEB)

    Hostick, C.J.

    1990-12-01

    This report was prepared by the Pacific Northwest Laboratory to summarize existing and emerging information system technology and standards applicable to Depot System Command (DESCOM) modernization efforts. The intent of this summarization is to provide the Revitalization of Army Depots for the Year 2000 (READY 2000) team a clear understanding of the enabling information system technologies required to support effective modernization activities. Much of the information contained in this report was acquired during the last year in support of the US Army Armament, Munitions, and Chemical Command (AMCCOM) Facility Integrated Manufacturing Management System (FIMMS) project at PNL, which is targeting the modernization of plant-wide information systems at Army Ammunition Plants. The objective of information system modernization is to improve the effectiveness of an organization in performing its mission. Information system modernization strives to meet this objective by creating an environment where data is electronically captured near the source and readily available to all areas of the organization. Advanced networks, together with related information system technology, are the enabling mechanisms that make modern information system infrastructures possible. The intent of this paper is to present an overview of advanced information system network technology to support depot modernization planners in making technology management decisions. Existing and emerging Open System Interconnection (OSI) and Government Open System Interconnection Profile (GOSIP) standards are explained, as well as a brief assessment of existing products compliant with these standards. Finally, recommendations for achieving plant-wide integration using existing products are presented, and migration strategies for full OSI compliance are introduced. 5 refs., 16 figs. (JF)

  20. Monitoring water quality in Sydney Harbour using blue mussels during remediation of the Sydney Tar Ponds, Nova Scotia, Canada.

    Science.gov (United States)

    Walker, Tony R; MacAskill, Devin

    2014-03-01

    Using mussels as monitoring tools we measured water quality in Sydney Harbour during a large scale, multi-year remediation project of the Sydney Tar Ponds (STPs); one of Canada's most contaminated sites. Chemical contaminants were measured in blue mussels (Mytilus edulis) in Sydney Harbour, which were used as monitoring tools to assess the spatio-temporal distribution of polycyclic aromatic hydrocarbons (PAHs); polychlorinated biphenyls (PCBs); metals (As, Cd, Cu, Hg, Pb, Zn) and lipid content during baseline and 3 years of remediation. The overall spatio-temporal distribution of chemicals in mussels was also compared to contaminants in other marine indicators (e.g., sediment, water and crab tissue). Measured metal concentrations in mussels showed some minor temporal variability (4 years), but these did not appear to be directly related to remediation activities, with the highest concentrations of As, Hg and Zn measured at reference stations. Most measured contaminants showed stable or potentially decreasing concentrations during the study, except Pb and Zn. Individual PAH compounds were mostly undetected during baseline and remediation, except for fluoranthene and pyrene. Concentrations of fluoranthene in mussels and deep water samples were moderately related. Generally, PCBs were undetected (remediation at some near-field stations. Contaminants measured during this study were at much lower concentrations than previously reported in other studies of mussels in Sydney Harbour and eastern Canada. This is likely due to the ongoing natural recovery of Sydney Harbour and to a lesser extent because of the environmental mitigation protection measures implemented during remediation activities at the STPs. The lack of detection of most individual PAHs and PCBs, plus relatively low bio-accumulation of metals observed during baseline and remediation attest to the effectiveness of using mussels as monitoring tools for environmental quality.

  1. Hepatitis A and travel amongst Nova Scotia postsecondary students: evidence for a targeted vs. universal immunization strategy.

    Science.gov (United States)

    Matheson, Katherine; Halperin, Beth; McNeil, Shelly; Langley, Joanne M; Mackinnon-Cameron, Donna; Halperin, Scott A

    2010-11-29

    Canadian guidelines recommend hepatitis A virus (HAV) vaccination for high-risk persons, such as travelers to HAV-endemic areas. The US CDC advocates universal immunization. To explore whether a universal strategy for HAV immunization rather than the Canadian targeted approach for travelers is justified by measuring compliance of postsecondary students with Canadian guidelines. A cross-sectional study using an electronic survey method elicited HAV risk factors, immunization history, disease status, and factors affecting immunization status from postsecondary students. Seropositivity was determined by measuring HAV antibodies in saliva from a convenience sample of survey participants within each study group. Statistical analysis used Fisher's exact test and logistic regression. We received 2279 completed surveys (10.6% response) and 235 saliva samples (58.7% response). A total of 1380 (60.6%) participants had traveled to HAV-endemic regions and 1851 (81.2%) were planning to do so within the next 5 years. Less than half who traveled to HAV-endemic areas reported a history of HAV vaccination (48.0%). HAV seropositivity rates were higher amongst those who traveled to (63.6%) or were planning to travel to (55.0%) HAV-endemic areas than those who had never traveled or had no plans to travel to such areas (17.4%). Only 8.9% of unvaccinated students were seropositive (5.3% of Canadian-born students). Amongst unvaccinated, seropositive students, there was a nonsignificant trend for higher seropositivity in those who had previously traveled to HAV-endemic areas (14.7%) than those who had not traveled abroad (4.4%), suggesting an exposure to HAV during travel. Nearly all (96.5%) unvaccinated students, who were willing to be vaccinated based on current knowledge or if their doctor recommended it, indicated a willingness to receive vaccine if it were provided free of charge. Current Canadian guidelines for HAV vaccination are not being followed within the postsecondary student population. Given high rates of travel to HAV-endemic areas in this population, a universal approach to HAV vaccination may be warranted. Copyright © 2010 Elsevier Ltd. All rights reserved.

  2. Recovery of Cephalosporin Resistant Escherichia coli and Salmonella from Pork, Beef and Chicken Marketed in Nova Scotia

    Directory of Open Access Journals (Sweden)

    Kevin R Forward

    2004-01-01

    Full Text Available BACKGROUND: Antimicrobial use in farm animals is a potentially important contributor to the emergence of antimicrobial resistance. Resistant Salmonella may lead to serious human infections and resistant Escherichia coli may transfer plasmid-encoded resistance genes to other pathogens.

  3. Negotiated risk and resident autonomy: Frontline care staff perspectives on culture change in long term care in Nova Scotia, Canada.

    Science.gov (United States)

    Roberts, Emily

    2016-08-12

    Regulating risk, freedom of action, and autonomy in decision making are problems shared by both caregivers and residents in long term care settings, and may become the subject of tension and constant negotiation. This study focuses on long term care staff and management perceptions of day to day life in a care community which has gone through a culture change transition, where small residentially scaled households replace large instutional models of care. In each household, the setting is considered to be home for the 8-12 residents, creating a major shift of roles for the caregivers; they are, in essence, coming into a home rather than institutional environment as a place of work. This potentially changes the dynamics of both patterns of work for caregivers and patterns of daily living for residents. Participant observations and care staff interviews. Several key themes emrged which include: teamwork; the culture of care; regulating risk; the physical environment and care staff empowerment. An unexpected outcome was the consensus among care staff that it is they who feel at home while working in the care households, leading to empowerment in their work roles and a deeper understanding of the importance of their role in the lives of the residents.

  4. Persistence and degradation of the herbicide hexazinone in soils of lowbush blueberry fields in Nova Scotia, Canada

    International Nuclear Information System (INIS)

    Jensen, K.I.N.; Kimball, E.R.

    1987-01-01

    Hexazinone is a broad spectrum herbicide used primarily in forestry, industrial and right-of-way weed control. Hexazinone is very water soluble. It readily leaches in soils and, depending on rainfall and slope, can be transported laterally following surface applications. Eight metabolites were extracted from 14 C-hexazinone treated soils and metabolite C was the major metabolite at each location. Hexazinone is degraded primarily by microorganisms in the soil with little degradation occurring under sterile or anaerobic conditions. The native lowbush blueberry (Vaccinium angustifolium) is tolerant to hexazinone at rates that give selective control of many weedy species associated with this crop. This blueberry is an important fruit crop of Maine and the Eastern Canadian provinces where commercial fields have been developed by management of wild stands originating from forests or abandoned farmland. Hexazinone is now widely used in all blueberry producing areas with thousands of hectares treated annually. The following study examines the fate of this 14 C-labelled herbicide in several typical soil types in the field and under laboratory conditions

  5. Communication, Collaboration and Cooperation: An Evaluation of Nova Scotia's Borrow Anywhere, Return Anywhere (BARA) Multi-Type Library Initiative

    Science.gov (United States)

    van den Hoogen, Suzanne; Parrott, Denise

    2012-01-01

    Partnerships and collaborations among libraries are proven to enhance collective resources. The collaboration of multi-type libraries offers a unique opportunity to explore the potential of different libraries working together to provide the best possible service to their community members. This article provides a detailed report of a multi-type…

  6. Deposition of a saline giant in the Mississippian Windsor Group, Nova Scotia, and the nascent Late Paleozoic Ice Age

    Science.gov (United States)

    MacNeil, Laura A.; Pufahl, Peir K.; James, Noel P.

    2018-01-01

    Saline giants are vast marine evaporite deposits that currently have no modern analogues and remain one of the most enigmatic of chemical sedimentary rocks. The Mississippian Windsor Group (ca. 345 Ma), Maritimes Basin, Atlantic Canada is a saline giant that consists of two evaporite-rich sedimentary sequences that are subdivided into five subzones. Sequence 1 is composed almost entirely of thick halite belonging to Subzone A (Osagean). Sequence 2 is in unconformable contact and comprised of stacked carbonate-evaporite peritidal cycles of Subzones B through E (Meramecian). Subzone B, the focus of research herein, documents the transition from wholly evaporitic to open marine conditions and thus, preserves an exceptional window into the processes forming saline giants. Lithofacies stacking patterns in Subzone B reveal that higher-order fluctuations in relative sea level produced nine stacked parasequences interpreted to reflect high frequency glacioeustatic oscillations during the onset of the Late Paleozoic Ice Age. Each parasequence reflects progradation of intertidal and sabkha sediments over subtidal carbonate and evaporite deposits. Dissimilarities in cycle composition between sub-basins imply the development of contrasting brine chemistries from differing recharge rates with the open ocean. What the Windsor Group shows is that evaporite type is ostensibly linked to the amplitude and frequency of sea level rise and fall during deposition. True saline giants, like the basinwide evaporites of Sequence 1, apparently require low amplitude, long frequency changes in sea level to promote the development of stable brine pools that are only periodically recharged with seawater. By contrast, the high amplitude, short frequency glacioeustatic variability in sea level that controlled the accumulation of peritidal evaporites in Subzone B produce smaller, subeconomic deposits with more complex facies relationships.

  7. Ichthyoplankton Abundance and Distribution Model within the Gulf of Maine from Cape Sable, Nova Scotia to southern Massachusetts

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Fisheries Service's Northeast Fisheries Science Center conducted standardized ichthyoplankton surveys from 1977-1988 along the continental shelf...

  8. Space Transportation Infrastructure Supported By Propellant Depots

    Science.gov (United States)

    Smitherman, David; Woodcock, Gordon

    2012-01-01

    A space transportation infrastructure is described that utilizes propellant depot servicing platforms to support all foreseeable missions in the Earth-Moon vicinity and deep space out to Mars. The infrastructure utilizes current expendable launch vehicle (ELV) systems such as the Delta IV Heavy, Atlas V, and Falcon 9, for all crew, cargo, and propellant launches to orbit. Propellant launches are made to Low-Earth-Orbit (LEO) Depot and an Earth-Moon Lagrange Point 1 (L1) Depot to support a new reusable in-space transportation vehicles. The LEO Depot supports missions to Geosynchronous Earth Orbit (GEO) for satellite servicing and to L1 for L1 Depot missions. The L1 Depot supports Lunar, Earth-Sun L2 (ESL2), Asteroid and Mars Missions. New vehicle design concepts are presented that can be launched on current 5 meter diameter ELV systems. These new reusable vehicle concepts include a Crew Transfer Vehicle (CTV) for crew transportation between the LEO Depot, L1 Depot and missions beyond L1; a new reusable lunar lander for crew transportation between the L1 Depot and the lunar surface; and Mars orbital Depot are based on International Space Station (ISS) heritage hardware. Data provided includes the number of launches required for each mission utilizing current ELV systems (Delta IV Heavy or equivalent) and the approximate vehicle masses and propellant requirements. Also included is a discussion on affordability with ideas on technologies that could reduce the number of launches required and thoughts on how this infrastructure include competitive bidding for ELV flights and propellant services, developments of new reusable in-space vehicles and development of a multiuse infrastructure that can support many government and commercial missions simultaneously.

  9. Storage depot for radioactive material

    International Nuclear Information System (INIS)

    Szulinski, M.J.

    1983-01-01

    Vertical drilling of cylindrical holes in the soil, and the lining of such holes, provides storage vaults called caissons. A guarded depot is provided with a plurality of such caissons covered by shielded closures preventing radiation from penetrating through any linear gap to the atmosphere. The heat generated by the radioactive material is dissipated through the vertical liner of the well into the adjacent soil and thus to the ground surface so that most of the heat from the radioactive material is dissipated into the atmosphere in a manner involving no significant amount of biologically harmful radiation. The passive cooling of the radioactive material without reliance upon pumps, personnel, or other factor which might fail, constitutes one of the most advantageous features of this system. Moreover this system is resistant to damage from tornadoes or earthquakes. Hermetically sealed containers of radioactive material may be positioned in the caissons. Loading vehicles can travel throughout the depot to permit great flexibility of loading and unloading radioactive materials. Radioactive material can be shifted to a more closely spaced caisson after ageing sufficiently to generate much less heat. The quantity of material stored in a caisson is restricted by the average capacity for heat dissipation of the soil adjacent such caisson

  10. DEPOT database: Reference manual and user's guide

    International Nuclear Information System (INIS)

    Clancey, P.; Logg, C.

    1991-03-01

    DEPOT has been developed to provide tracking for the Stanford Linear Collider (SLC) control system equipment. For each piece of equipment entered into the database, complete location, service, maintenance, modification, certification, and radiation exposure histories can be maintained. To facilitate data entry accuracy, efficiency, and consistency, barcoding technology has been used extensively. DEPOT has been an important tool in improving the reliability of the microsystems controlling SLC. This document describes the components of the DEPOT database, the elements in the database records, and the use of the supporting programs for entering data, searching the database, and producing reports from the information

  11. Depot Medroxyprogesterone Acetate (Depo-Provlera) as a Contrac ...

    African Journals Online (AJOL)

    Depot Medroxyprogesterone Acetate (Depo-Provlera) as a Contrac·eptive Preparation. Basil Bloch. Abstract. Experience with depot medroxyprogesterone acetate as a contraceptive preparation in 7 335 patients for a total of 38 714 months over a 3-year period is described. The discontinuation rate was 18.3% and the ...

  12. Ligand Depot: a data warehouse for ligands bound to macromolecules.

    Science.gov (United States)

    Feng, Zukang; Chen, Li; Maddula, Himabindu; Akcan, Ozgur; Oughtred, Rose; Berman, Helen M; Westbrook, John

    2004-09-01

    Ligand Depot is an integrated data resource for finding information about small molecules bound to proteins and nucleic acids. The initial release (version 1.0, November, 2003) focuses on providing chemical and structural information for small molecules found as part of the structures deposited in the Protein Data Bank. Ligand Depot accepts keyword-based queries and also provides a graphical interface for performing chemical substructure searches. A wide variety of web resources that contain information on small molecules may also be accessed through Ligand Depot. Ligand Depot is available at http://ligand-depot.rutgers.edu/. Version 1.0 supports multiple operating systems including Windows, Unix, Linux and the Macintosh operating system. The current drawing tool works in Internet Explorer, Netscape and Mozilla on Windows, Unix and Linux.

  13. The Westphalian D fossil lepidodendrid forest at Table Head, Sydney Basin, Nova Scotia: Sedimentology, paleoecology and floral response to changing edaphic conditions

    Science.gov (United States)

    Calder, J.H.; Gibling, M.R.; Eble, C.F.; Scott, A.C.; MacNeil, D.J.

    1996-01-01

    Strata of Westphalian D age on the western coast of the Sydney Basin expose a fossil forest of approximately 30 lepidodendrid trees within one of several clastic splits of the Harbour Seam. A mutidisciplinary approach was employed to interpret the origins of the coal bed, the depositional history of the site and the response of the fossil forest to changing edaphic conditions. The megaspore and miospore records indicate that the mire vegetation was dominated by arboreous lycopsids, especially Paralycopodites, with subdominant tree ferns. Petrographic, palynological and geochemical evidence suggest that the Harbour coal bed at Table Head originated as a rheotrophic (cf. planar) mire (eutric histosol). The mire forest is interpreted to have been engulfed by prograding distributary-channel sediments; sparse protist assemblages are suggestive of a freshwater delta-plain lake environment occasionally in contact with brackish waters. Lepidodendrids persisted as site colonizers of clastic substrates even after burial of the rheotrophic peatland and influenced the morphology of deposited sediment, but apparently were unable to colonize distributary channels. Equivocal taxonomic data (compression fossils) show the fossil forest to have been composed of both monocarpic (Lepidodendron) and polycarpic (Diaphorodendron, Paralycopodites, ?Sigillaria) lycopsids, genera recorded in the palynology of the uppermost ply of the underlying coal bed. Comparatively rare within the clastic beds of the fossil forest, however, is the stem compression of Paralycopodites, whose dispersed megapores and miospores dominate the underlying coal bed. Tree diameter data recorded equivalent to breast height indicate a forest of mixed age. These data would appear to suggest that some lepidodendrids employing a polycarpic reproductive strategy were better able to cross the ecological barrier imposed between peat and clastic substrates. Foliar compressions indicate that an understory or stand of Psaronius type tree ferns co-existed with the lepidodendrids on clastic substrates, which developed as incipient gleysol soils. The entombment of the forest can be ascribed to its distributary coastal setting, local subsidence and a seasonal climate that fostered wildfire and increased sedimentation.

  14. Review of: An analysis of flooding in Elk River and Freshwater Creek watersheds, Humboldt County, California (prepared by The Pacific Lumber Company, Scotia, California)

    Science.gov (United States)

    L. M. Reid

    1999-01-01

    The reviewed report (PL 1999) attempts to demonstrate that logging conducted over the past decade or so in Freshwater and Elk watersheds has not caused increased flooding in downstream portions of the watersheds. However, most of the report's sections include information that supports the hypothesis that logging has aggravated flood hazard, produce conclusions...

  15. A small-area analysis of inequalities in chronic disease prevalence across urban and non-urban communities in the Province of Nova Scotia, Canada, 2007-2011.

    Science.gov (United States)

    Terashima, Mikiko; Rainham, Daniel G C; Levy, Adrian R

    2014-05-13

    Small-area studies of health inequalities often have an urban focus, and may be limited in their translatability to non-urban settings. Using small-area units representing communities, this study assessed the influence of living in different settlement types (urban, town and rural) on the prevalence of four chronic diseases (heart disease, cancer, diabetes and stroke) and compared the degrees of associations with individual-level and community-level factors among the settlement types. The associations between community-level and individual-level characteristics and prevalence of the chronic diseases were assessed using logistic regression (multilevel and non-multilevel) models. Individual-level data were extracted from the Canadian Community Health Survey (2007-2011). Indices of material deprivation and social isolation and the settlement type classification were created using the Canadian Census. Respondents living in towns were 21% more likely to report one of the diseases than respondents living in urban communities even after accounting for individual-level and community-level characteristics. Having dependent children appeared to have protective effects in towns, especially for males (OR: 0.49 (95% CI 0.27 to 0.90)). Unemployment had a strong association for all types of communities, but being unemployed appeared to be particularly damaging to health of males in urban communities (OR: 2.48 (95% CI 1.43 to 4.30)). The study showed that those living in non-urban settings, particularly towns, experience extra challenges in maintaining health above and beyond the socioeconomic condition and social isolation of the communities, and individual demographic, behavioural and socioeconomic attributes. Our findings also suggest that health inequality studies based on urban-only settings may underestimate the risks by some factors. Ways to devise meaningful small-area units comparable in all settlement types are necessary to help plan effective provision of chronic disease-related health services and programmes on a regional scale. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  16. An autochthonous Avalonian basement source for the latest Ordovician Brenton Pluton in the Meguma terrane of Nova Scotia: U-Pb-Hf isotopic constraints and paleogeographic implications

    Science.gov (United States)

    Duncan Keppie, J.; Gregory Shellnutt, J.; Dostal, Jaroslav; Fraser Keppie, D.

    2018-04-01

    The Ediacaran-Ordovician Meguma Supergroup was thrust over Avalonia basement prior to the intrusion of post-Acadian, ca. 370 Ma, S-type granitic batholiths. This has led to two main hypotheses regarding the original location of the Meguma terrane, a continental rise prism bordering either NW Africa or Avalonia. On the other hand, the pre-Acadian, ca. 440 Ma Brenton pluton has yielded the following U/Pb LA-ICP-MS zircon data: (1) 448 ± 3 Ma population peak inferred to be the intrusive age and (2) ca. 550 and 700 Ma inherited ages common to both Avalonia and NW Africa. In contrast, Hf isotopic analyses of zircon yielded model ages ranging from 814 to 1127 Ma with most between 940 and 1040 Ma: such ages are typical of Avalonia and not NW Africa. The ages of the inherited zircons found within the Brenton pluton suggest that it was probably derived by partial melting of sub-Meguma, mid-crustal Avalonian rocks, upon which the Meguma Supergroup was deposited. Although Avalonia is commonly included in the peri-Gondwanan terranes off NW Africa or Amazonia, paleomagnetic data, faunal provinciality, and Hf data suggest that, during the Ediacaran-Early Cambrian, it was an island chain lying near the tropics (ca. 20-30 °S) and was possibly a continuation of the Bolshezemel volcanic arc accreted to northern Baltica during the Ediacaran Timanide orogenesis. This is consistent with the similar derital zircon population in the Ediacaran-Cambrian Meguma Supergroup and the Dividal Group in northeastern Baltica.

  17. The Preliminary Findings of a Study Exploring the Perceptions of a Sample of Young Heterosexual Males regarding HIV Prevention Education Programming in Nova Scotia, Canada

    Science.gov (United States)

    Gahagan, Jacqueline; Rehman, Laurene; Barbour, Laura; McWilliam, Susan

    2007-01-01

    Despite the increasing numbers of young Canadian females becoming infected with HIV through heterosexual transmission with an infected male sexual partner, the majority of current HIV prevention programs and services in Canada continue to ignore the needs of young heterosexual males. This research is derived from 30 in-depth interviews, 9 focus…

  18. "Review of the Sustained Yield Plan / Habitat Conservation Plan for the properties of The Pacific Lumber Company, Scotia Pacific Holding Company, and Salmon Creek Corporation"

    Science.gov (United States)

    Leslie M. Reid

    1998-01-01

    Downstream impacts to aquatic environments and property generally occur as cumulative watershed impacts, which are usually caused by changes in the transport of woody debris, water, and sediment through a watershed. The downstream cumulative impacts that are likely to accrue from implementation of the Sustained Yield Plan / Habitat Conservation Plan for the properties...

  19. Nova Scotia: ``Feu Follet" At Cheticamp, and Also the Phenomena At L'Sitkuk of the Mi'Kmaw, May Be Electromagnetic In Nature.

    Science.gov (United States)

    Ochs, Michael Ann; McLeod, Roger D.

    2001-11-01

    There is a strong tradition that ``feu follet" exists at the cemetery associated with the Acadian French at Cheticamp. It is described as a blue light, and may actually be the equivalent of an ascending, positively charged stream of ions in the atmosphere, just like the blue-light column that is often a precursor of a storm's lightning-strike. Similar phenomena are at America's Stonehenge, at a stone serpent effigy site in Ohio, and just north of the Lakes Memphremagog and Magog of Vermont and Canada. At the Bear River L'sitkuk Reservation area, which seems to us to have been a most unsuitable site, was deliberately chosen by the Mi'kmaw for their living area. Was this because certain properties of the electromagnetic field (EMF) are evident to them there, which also seem to be reflected in their legends? We hope to establish that these disparate cultures and their separate worldviews can be confirmed by the presence of particular EMF signatures. *This paper does not represent the views of the United States Environmental Protection Agency.

  20. Protective associations of importance of religion and frequency of service attendance with depression risk, suicidal behaviours and substance use in adolescents in Nova Scotia, Canada.

    Science.gov (United States)

    Rasic, Daniel; Kisely, Steve; Langille, Donald B

    2011-08-01

    We examined relationships of measures of personal importance of religion and frequency of attendance at religious services with risk of depression and risk behaviours in high school students in Cape Breton, Canada. We examined the impact of confounding and explanatory factors on these relationships. Data were drawn from self-report surveys of adolescents aged 15-19 (N=1615) at three high schools in May, 2006. We used logistic regression to assess associations of religious importance and religious service attendance with risk of depression, suicidal behaviour, binge drinking and frequent marijuana use, controlling in multivariate models for sociodemographic factors, family structure and social capital. Among females, higher personal importance of religion was associated with decreased odds of depression, suicidal ideation, drinking and marijuana use, while more religious attendance was protective for substance use behaviours and suicidal ideation. In males, both measures of religiosity were associated with decreased substance use. In multivariate models, religious importance had weak protective effects for depression and suicidal thinking in females, which were respectively modified by social trust and substance use. Attendance was protective for suicidal thinking in females, and was modified by depression. These associations were not seen in males. Attendance was consistently associated with less substance use in females, while importance was not. Importance was consistently protective for marijuana use and attendance was protective for binge drinking in males. This was a cross-sectional self-report survey and causality cannot be inferred. Protective associations of measures of religiosity are seen in Canadian adolescents, as they are elsewhere. Copyright © 2011 Elsevier B.V. All rights reserved.

  1. The writing of 'The Westray Story': a discourse analysis of the aftermath of the Westray coal mine explosion (Nova Scotia)

    Energy Technology Data Exchange (ETDEWEB)

    Dodd, S.M. [York University (Canada). Toronto, ON (Canada). Department of Sociology

    2002-07-01

    This is a critical discourse analysis of the report of the public inquiry of the Westray mining disaster. The conflicting interests and values of the factions involved, the availability of information in the workplace, and the assignment of blame for the disaster are among the factors considered. The 'new prudentialism' that holds individuals responsible for risk assessment and avoidance, but forces them to act within the organizational framework, is discussed.

  2. Patterns of fisheries institutional failure and success: experience from the Southern Gulf of St. Lawrence snow crab fishery in Nova Scotia, Canada

    NARCIS (Netherlands)

    Loucks, L.

    2007-01-01

    This paper examines why market and government institutions failed to prevent over fishing in the Southern Gulf snow crab fishery, whereas non-market institutions succeeded. A general conclusion is that the institutional environment in which economic behaviour must be coordinated for successful

  3. Seasonal cycle of circulation in the Antarctic Peninsula and the off-shelf transport of shelf waters into southern Drake Passage and Scotia Sea

    Science.gov (United States)

    Jiang, Mingshun; Charette, Matthew A.; Measures, Christopher I.; Zhu, Yiwu; Zhou, Meng

    2013-06-01

    The seasonal cycle of circulation and transport in the Antarctic Peninsula shelf region is investigated using a high-resolution (˜2 km) regional model based on the Regional Oceanic Modeling System (ROMS). The model also includes a naturally occurring tracer with a strong source over the shelf (radium isotope 228Ra, t1/2=5.8 years) to investigate the sediment Fe input and its transport. The model is spun-up for three years using climatological boundary and surface forcing and then run for the 2004-2006 period using realistic forcing. Model results suggest a persistent and coherent circulation system throughout the year consisting of several major components that converge water masses from various sources toward Elephant Island. These currents are largely in geostrophic balance, driven by surface winds, topographic steering, and large-scale forcing. Strong off-shelf transport of the Fe-rich shelf waters takes place over the northeastern shelf/slope of Elephant Island, driven by a combination of topographic steering, extension of shelf currents, and strong horizontal mixing between the ACC and shelf waters. These results are generally consistent with recent and historical observational studies. Both the shelf circulation and off-shelf transport show a significant seasonality, mainly due to the seasonal changes of surface winds and large-scale circulation. Modeled and observed distributions of 228Ra suggest that a majority of Fe-rich upper layer waters exported off-shelf around Elephant Island are carried by the shelfbreak current and the Bransfield Strait Current from the shallow sills between Gerlache Strait and Livingston Island, and northern shelf of the South Shetland Islands, where strong winter mixing supplies much of the sediment derived nutrients (including Fe) input to the surface layer.

  4. The combined impact of diet, physical activity, sleep and screen time on academic achievement: a prospective study of elementary school students in Nova Scotia, Canada.

    Science.gov (United States)

    Faught, Erin L; Ekwaru, John P; Gleddie, Douglas; Storey, Kate E; Asbridge, Mark; Veugelers, Paul J

    2017-03-09

    Few studies have investigated the independent associations of lifestyle behaviors (diet, physical activity, sleep, and screen time) and body weight status with academic achievement. Even fewer have investigated the combined effect of these behaviors on academic achievement. We hypothesize that the combined effect of these behaviors will have a higher impact on academic achievement than any behavior alone, or that of body weight status. In 2011, 4253 grade 5 (10-11 years old) students and their parents were surveyed about the child's diet, physical activity, screen time and sleep. Students' heights and weights were measured by research assistants. Academic achievement was measured using provincial standardized exams in mathematics, reading and writing, and was expressed as 'meeting' or 'not meeting' expectations as per standardized criterion. Exams were written 1 year following the measurement of lifestyle behaviors. Lifestyle behaviors were measured with self- and parental proxy reports and expressed as meeting recommendations (yes/no) for each behavior. Mixed effects logistic regression models adjusting for demographic confounders and caloric intake were used to determine the independent and combined associations. Meeting dietary recommendations was associated with increased likelihood of meeting academic expectations for each of math, reading and writing. Meeting recommendations for screen time and sleep was associated with meeting expectations for writing. For all three subjects, meeting additional lifestyle behavior recommendations was associated with higher likelihood of meeting expectations. Children who met 7-9 lifestyle behavior recommendations had greater than three-times the odds of meeting expectations for reading compared to those who met 0-3 recommendations (OR: 3.07, 95% CI: 2.09, 4.51), and 1.47 and 2.77 times the odds of meeting expectations in mathematics and writing, respectively. Body weight status was not associated with academic achievement. We found that lifestyle behaviors, not body weight status, are strongly associated with student academic performance. Promoting compliance with established healthy lifestyle recommendations could improve both the health and educational outcomes of school-aged children. School-based health promotion initiatives that target multiple lifestyle behaviors may have a greater effect on academic achievement than those that focus on a single behavior.

  5. Examination of adipose depot-specific PPAR moieties

    Energy Technology Data Exchange (ETDEWEB)

    Dodson, M.V., E-mail: dodson@wsu.edu [Department of Animal Sciences, Washington State University, Pullman, WA 99164 (United States); Vierck, J.L. [Department of Animal Sciences, Washington State University, Pullman, WA 99164 (United States); Hausman, G.J. [USDA-ARS, Richard B. Russell Agricultural Research Station, Athens, GA 30604 (United States); Guan, L.L. [Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, T6G 2P5 Canada (Canada); Fernyhough, M.E. [The Hartz Mountain Corporation, Secaucus, NJ 07094 (United States); Poulos, S.P. [The Coca-Cola Company, Research and Technology, Atlanta, GA 30313 (United States); Mir, P.S. [Agriculture and Agri-Food Canada Research Centre, Lethbridge, CA T1J 4B1 (United States); Jiang, Z. [Department of Animal Sciences, Washington State University, Pullman, WA 99164 (United States)

    2010-04-02

    Molecular mechanisms of peroxisome proliferator activated receptors (PPARs) are being defined rapidly, as illustrated by the volume of papers published. Much of the research is directed towards a clinical end-point/application; however, the non-homogeneous nature of adipose depots in laboratory animals is spurring similar research in domestic meat animals (such as beef cattle). Moreover, the size of adipose depots in meat animals remains an attractive feature for using them to obtain cells for PPAR research. Examination of meat-animal depot-specific PPAR moieties may provide novel information about adipocyte regulation that might be extrapolated to all animals.

  6. Examination of adipose depot-specific PPAR moieties

    International Nuclear Information System (INIS)

    Dodson, M.V.; Vierck, J.L.; Hausman, G.J.; Guan, L.L.; Fernyhough, M.E.; Poulos, S.P.; Mir, P.S.; Jiang, Z.

    2010-01-01

    Molecular mechanisms of peroxisome proliferator activated receptors (PPARs) are being defined rapidly, as illustrated by the volume of papers published. Much of the research is directed towards a clinical end-point/application; however, the non-homogeneous nature of adipose depots in laboratory animals is spurring similar research in domestic meat animals (such as beef cattle). Moreover, the size of adipose depots in meat animals remains an attractive feature for using them to obtain cells for PPAR research. Examination of meat-animal depot-specific PPAR moieties may provide novel information about adipocyte regulation that might be extrapolated to all animals.

  7. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2016-01-01

    We study a location-routing problem in the context of capacitated vehicle routing. The input to the k-location capacitated vehicle routing problem (k-LocVRP) consists of a set of demand locations in a metric space and a fleet of k identical vehicles, each of capacity Q. The objective is to locate k...... depots, one for each vehicle, and compute routes for the vehicles so that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for k-LocVRP. In obtaining this result, we introduce a common generalization of the k-median and minimum...... spanning tree problems (called k median forest), which might be of independent interest. We give a local-search based (3+ε)-approximation algorithm for k median forest, which leads to a (12+ε)-approximation algorithm for k-LocVRP, for any constant ε>0....

  8. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2016-01-01

    depots, one for each vehicle, and compute routes for the vehicles so that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for k-LocVRP. In obtaining this result, we introduce a common generalization of the k-median and minimum...... spanning tree problems (called k median forest), which might be of independent interest. We give a local-search based (3+ε)-approximation algorithm for k median forest, which leads to a (12+ε)-approximation algorithm for k-LocVRP, for any constant ε>0.......We study a location-routing problem in the context of capacitated vehicle routing. The input to the k-location capacitated vehicle routing problem (k-LocVRP) consists of a set of demand locations in a metric space and a fleet of k identical vehicles, each of capacity Q. The objective is to locate k...

  9. Expandable Cryogenic Tankage for On Orbit Depot Storage, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed expandable depot storage tanks would make it possible to have an on-orbit tank larger in volume than any existing or planned launch vehicles. The size...

  10. Spatial Analysis of Depots for Advanced Biomass Processing

    Energy Technology Data Exchange (ETDEWEB)

    Hilliard, Michael R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brandt, Craig C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Webb, Erin [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Sokhansanj, Shahabaddine [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Eaton, Laurence M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Martinez Gonzalez, Maria I. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2014-09-01

    The objective of this work was to perform a spatial analysis of the total feedstock cost at the conversion reactor for biomass supplied by a conventional system and an advanced system with depots to densify biomass into pellets. From these cost estimates, the conditions (feedstock cost and availability) for which advanced processing depots make it possible to achieve cost and volume targets can be identified.

  11. Locating Depots for Capacitated Vehicle Routing

    DEFF Research Database (Denmark)

    Gørtz, Inge Li; Nagarajan, Viswanath

    2011-01-01

    that all demands are satisfied and the total cost is minimized. Our main result is a constant-factor approximation algorithm for k-LocVRP. To achieve this result, we reduce k-LocVRP to the following generalization of k median, which might be of independent interest. Given a metric (V, d), bound k...... median forest, which leads to a (12+E)-approximation algorithm for k-LocVRP, for any constant E > 0. The algorithm for k median forest is t-swap local search, and we prove that it has locality gap 3 + 2 t ; this generalizes the corresponding result for k median [3]. Finally we consider the k median......We study a location-routing problem in the context of capacitated vehicle routing. The input to k-LocVRP is a set of demand locations in a metric space and a fleet of k vehicles each of capacity Q. The objective is to locate k depots, one for each vehicle, and compute routes for the vehicles so...

  12. Architecture Study for a Fuel Depot Supplied from Lunar Assets

    Science.gov (United States)

    Perrin, Thomas M.; Casler, James G.

    2016-01-01

    This architecture study sought to determine the optimum architecture for a fuel depot supplied from lunar assets. Four factors - the location of propellant processing (on the Moon or on the depot), the depot location (on the Moon, L1, GEO, or LEO), the propellant transfer location (L1, GEO, or LEO), and the propellant transfer method (bulk fuel or canister exchange) were combined to identify 18 candidate architectures. Two design reference missions (DRMs) - a commercial satellite servicing mission and a Government cargo mission to Mars - created demand for propellants, while a propellant delivery DRM examined supply issues. The study concluded Earth-Moon L1 is the best location for an orbiting depot. For all architectures, propellant boiloff was less than anticipated, and was far overshadowed by delta-v requirements and resulting fuel consumption. Bulk transfer is the most flexible for both the supplier and customer. However, since canister exchange bypasses the transfer of bulk cryogens and necessary chilldown losses, canister exchange shows promise and merits further investigation. Overall, this work indicates propellant consumption and loss is an essential factor in assessing fuel depot architectures.

  13. Supply Inventory Management: Accountability and Control of Materiel at the Naval Air Depot, North Island

    National Research Council Canada - National Science Library

    2002-01-01

    ... of the $6.8 billion was for operation of three Naval Air Depots. A significant portion of the $1.5 billion was for purchasing materiel used in repair and overhaul processes at the depot maintenance facilities...

  14. Supply Inventory Managment: Accountability and Control of Materiel at the Naval Air Depot, North Island

    National Research Council Canada - National Science Library

    Young, Shelton

    2002-01-01

    ... of the $6.8 billion was for operation of three Naval Air Depots. A significant portion of the $1.5 billion was for purchasing materiel used in repair and overhaul processes at the depot maintenance facilities...

  15. Pengembangan Merek dan Pengkajian Strategi Pemasaran di Depot Rasa Suka Kediri

    OpenAIRE

    Raharjo, Rini; Surjani, Rosita Meitha; Rinawiyanti, Esti Dwi

    2013-01-01

    Depot Rasa Suka is a culinary business that provides a variety of Indonesian dishes. However people still do not know and yet loyal to Depot Rasa Suka due to the unavailability of parking space, quite a long serving time, hot room, less attractive promotion and room design. Therefore Depot Rasa Suka need to devise strategies to develop brands through brand equity analysis and improvement of brand elements as well as designing a marketing strategies. The goal of this research is to make Depot ...

  16. DEPOT: Database for electronics parts and other things

    International Nuclear Information System (INIS)

    Logg, C.A.; Clancey, P.W.; Crane, G.

    1990-01-01

    DEPOT has been developed to provide tracking for the Stanford Linear Collider (SLC) control system equipment. For each piece of equipment entered in the database, a complete service, maintenance, modification, certification, location history, and, optionally, a radiation exposure history, can be maintained. To facilitate data entry accuracy, efficiency, and consistency, barcoding technology has been used extensively. DEPOT has been an important tool in improving the reliability of the microsystems controlling SLC. It is now being adopted by other systems at SLAC. 6 refs., 6 figs

  17. NASA Shuttle Logistics Depot (NSLD) - The application of ATE

    Science.gov (United States)

    Simpkins, Lorenz G.; Jenkins, Henry C.; Mauceri, A. Jack

    1990-01-01

    The concept of the NASA Shuttle Logistics Depot (NSLD) developed for the Space Shuttle Orbiter Program is described. The function of the NSLD at Cape Canaveral is to perform the acceptance and diagnostic testing of the Shuttle's space-rated line-replaceable units and shop-replaceable units (SRUs). The NSLD includes a comprehensive electronic automatic test station, program development stations, and assorted manufacturing support equipment (including thermal and vibration test equipment, special test equipment, and a card SRU test system). The depot activities also include the establishment of the functions for manufacturing of mechanical parts, soldering, welding, painting, clean room operation, procurement, and subcontract management.

  18. Computer-aided acquisition and logistics support (CALS): Concept of Operations for Depot Maintenance

    Energy Technology Data Exchange (ETDEWEB)

    Bourgeois, N.C.; Greer, D.K.

    1993-04-01

    This CALS Concept of Operations for Depot Maintenance provides the foundation strategy and the near term tactical plan for CALS implementation in the depot maintenance environment. The user requirements enumerated and the overarching architecture outlined serve as the primary framework for implementation planning. The seamless integration of depot maintenance business processes and supporting information systems with the emerging global CALS environment will be critical to the efficient realization of depot user's information requirements, and as, such will be a fundamental theme in depot implementations.

  19. Orbiting Depot and Reusable Lander for Lunar Transportation

    Science.gov (United States)

    Petro, Andrew

    2009-01-01

    A document describes a conceptual transportation system that would support exploratory visits by humans to locations dispersed across the surface of the Moon and provide transport of humans and cargo to sustain one or more permanent Lunar outpost. The system architecture reflects requirements to (1) minimize the amount of vehicle hardware that must be expended while maintaining high performance margins and (2) take advantage of emerging capabilities to produce propellants on the Moon while also enabling efficient operation using propellants transported from Earth. The system would include reusable single- stage lander spacecraft and a depot in a low orbit around the Moon. Each lander would have descent, landing, and ascent capabilities. A crew-taxi version of the lander would carry a pressurized crew module; a cargo version could carry a variety of cargo containers. The depot would serve as a facility for storage and for refueling with propellants delivered from Earth or propellants produced on the Moon. The depot could receive propellants and cargo sent from Earth on a variety of spacecraft. The depot could provide power and orbit maintenance for crew vehicles from Earth and could serve as a safe haven for lunar crews pending transport back to Earth.

  20. New Insights into Drug Absorption from Oil Depots

    NARCIS (Netherlands)

    Kalicharan, R.W.

    2017-01-01

    Sustained delivery formulations are used in order to prolong the pharmacological activity of a drug. A commonly used parenteral sustained delivery formulation is an oil depot which consists of a solution of lipophilic molecules in a vegetable oil. These are normally administered either

  1. Whole tree transportation system for timber processing depots

    Science.gov (United States)

    John Lancaster; Tom Gallagher; Tim  McDonald; Dana Mitchell

    2016-01-01

    The growing demand for alternative energy has led those who are interested in producing sustainable energy from renewable timber to devise new concepts to satisfy those demands. The concept of timber processing depots, where whole stem trees will be delivered for future processing into wood products and high quality energy fuel, has led to the re-evaluation of our...

  2. Fatty acid composition of subcutaneous and kidney fat depots of ...

    African Journals Online (AJOL)

    60. Fatty acid composition of subcutaneous and kidney fat depots of Boer goats and the response to varying levels of maize meal. N.H. Casey" and W.A. van Niekerk. Department of Animal Science, Faculty of Agriculture,. University of Pretoria, Pretoria, 0002 Republic of South Africa. xTo whom correspondence should be ...

  3. Redistributing Stock in Library Systems with a Depot

    NARCIS (Netherlands)

    van der Heide, Gerlach; Roodbergen, Kees Jan; van Foreest, Nicky

    Public library organizations often utilize depots for carrying out shipments to libraries in case of stock-outs and for storing low demand rental items at low cost. Similar systems may be employed by rental companies for other rental products such as tools, DVDs, and jewelry. Since shipments deplete

  4. Master Environmental Plan: Fort Wingate Depot Activity, Gallup, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Biang, C.A.; Yuen, C.R.; Biang, R.P.; Antonopoulos, A.A.; Ditmars, J.D.

    1990-12-01

    The master environmental plan is based on an environmental assessment of the areas requiring environmental evaluation (AREEs) at Fort Wingate Depot Activity near Gallup, New Mexico. The Fort Wingate Depot Activity is slated for closure under the Base Closure and Realignment Act, Public Law 100--526. The MEP assesses the current status, describes additional data requirements, recommends actions for the sites, and establishes a priority order for actions. The plan was developed so that actions comply with hazardous waste and water quality regulations of the State of New Mexico and applicable federal regulations. It contains a brief history of the site, relevant geological and hydrological information, and a description of the current status for each AREE along with a discussion of the available site-specific data that pertain to existing or potential contamination and the impact on the environment. 35 refs., 27 figs., 23 tabs.

  5. Radiological Final Status Survey of the Hammond Depot, Hammond, Indiana

    International Nuclear Information System (INIS)

    Vitkus, T.J.

    2008-01-01

    ORISE conducted extensive scoping, characterization, and final status surveys of land areas and structures at the DNSC's Hammond Depot located in Hammond, Indiana in multiple phases during 2005, 2006 and 2007. This report provides a detailed discussion of the radiological survey planning, survey implementation, remediation, and the results for these activities supporting the conclusion that radioactive contamination previously identified at the Hammond Depot (HD) has been reduced to levels such that the site may be released without radiological restrictions. The objective of the radiological final status survey (FSS) was to obtain the data necessary to demonstrate compliance with the U.S. Nuclear Regulatory Commission (NRC)-approved site-specific derived concentration guideline levels (DCGLs) for both structural surfaces and outdoor areas (ORISE 2006a and NRC 2007). The DCGLs were modeled such that any residual licensed material would not exceed the NRC's basic dose limit for license termination of 25 millirem per year (mrem/y)

  6. Use of depot medroxyprogesterone acetate and fracture risk

    OpenAIRE

    Meier, Christian; Brauchli, Yolanda B.; Jick, Susan S.; Kraenzlin, Marius E.; Meier, Christoph R.

    2010-01-01

    Depot medroxyprogesterone acetate (DMPA), which has a high rate of use among teenagers in Europe and the United States, has been associated with impaired bone mineral acquisition during adolescence and accelerated bone loss in later life. Studies on the association between DMPA use and fracture risk are limited.; We aimed at evaluating the relationship between use of hormonal contraceptives, specifically DMPA, and fracture risk.; We conducted a case-control analysis using the United Kingdom-b...

  7. Process and Energy Optimization Assessment, Tobyhanna Army Depot, PA

    Science.gov (United States)

    2006-04-17

    assembly of electronic-communication components, different welding processes are performed at TYAD. It uses shielded arc, metal inert gas (MIG...tungsten inert gas ( TIG ), and silver braz- ing oxygen/acetylene cutting plasma arc methods to complete mission re- quirements. Major welding jobs are...ER D C/ CE R L TR -0 6 -1 1 Process and Energy Optimization Assessment Tobyhanna Army Depot, PA Mike C.J. Lin, Alexander M. Zhivov

  8. Occupational Exposure of Petroleum Depot Workers to BTEX Compounds

    Directory of Open Access Journals (Sweden)

    M Rezazadeh Azari

    2011-12-01

    Full Text Available Background: Benzene, toluene, ethylbenzene and xylene (BTEX are the most important toxic volatile compounds in the air and could be easily absorbed through the respiratory tract. In recent years, the risk of exposure to BTEX compounds, especially benzene as a carcinogen, has been considered in petroleum depot stations. Objective: To assess the occupational exposure of petroleum depot workers in Iran to BTEX compounds. Methods: After completing a questionnaire and assessing occupational exposure to BTEX compounds, 78 (46 exposed and 32 non-exposed depot workers were randomly selected to participate in this study. Air sampling and analysis of BTEX was conducted according to the NIOSH method No. 1501. Analysis of urinary hippuric acid, as an indicator of toluene exposure, was carried out according to NIOSH method No. 8300. Personal monitoring of the high exposure group to BTEX compounds was repeated to verify the results obtained in the first phase of the monitoring. Results: Among the 9 operating groups studied, occupational exposure to benzene and toluene was higher in quality control and gasoline loading operators—the median exposure ranged from 0.16 to 1.63 ppm for benzene and 0.2 to 2.72 ppm for toluene. Median exposure of other group members to BTEX compounds was below the detection limit of analytical method (0.07, 0.06, 0.05, and 0.05 ppm, respectively. The level of toluene exposure measured showed correlation with neither post-shift urinary hippuric acid (Spearman's rho=0.128, p=0.982 nor with the difference between post- and pre-shift urinary hippuric acid (Spearman's rho=0.089, p=0.847 in depot operational workers. Conclusion: Gasoline loading operators are exposed to a relatively high level of benzene.

  9. [Treatment of Adult Schizophrenic Patients With Depot Antipsychotics].

    Science.gov (United States)

    Jaramillo González, Luis Eduardo; Gómez Restrepo, Carlos; García Valencia, Jenny; de la Hoz Bradford, Ana María; Ávila-Guerra, Mauricio; Bohórquez Peñaranda, Adriana

    2014-01-01

    To determine the indications of long-acting antipsychotic injection and what its effectiveness and safety in adult patients with schizophrenia during the treatment maintenance phase. A clinical practice guideline was elaborated under the parameters of the Methodological Guide of the Ministerio de Salud y Protección Social to identify, synthesize and evaluate the evidence and make recommendations about the treatment and follow-up of adult patients with schizophrenia. The evidence of NICE guide 82 was adopted and updated. The evidence was presented to the Guideline Developing Group and recommendations, employing the GRADE system, were produced. The literature review shows that the evidence has moderate to low quality. 8 articles were used. The risk of relapse was lower with depot risperidone and paliperidone palmitate when compared with placebo. For the risk of hospitalizations comparing depot antipsychotics (APD) versus oral AP, the result is inconclusive. Globally the second-generation APD had a lower risk of discontinuation when compared with placebo. The second generation AP had higher risk of extrapyramidal syndromes than placebo, as in the use of antiparkinsonian. The comparison of second-generation AP injections versus placebo showed an increased risk of early weight gain. The use of depot antipsychotics in the maintenance phase of adult patients diagnosed with schizophrenia is recommended if there is no adherence to oral antipsychotics as the patient's preference. It is not recommended depot antipsychotics in the acute phase of schizophrenia in adults. Copyright © 2014 Asociación Colombiana de Psiquiatría. Publicado por Elsevier España. All rights reserved.

  10. Depot Maintenance: Improvements to DODs Biennial Core Report Could Better Inform Oversight and Funding Decisions

    Science.gov (United States)

    2016-11-01

    military depots, and not workload performed by the private - sector . MDA officials told us that OSD guidance does not explain how to calculate the...military depots2—public- sector facilities that are government-owned and government-operated—and private - sector contractors. Depots have a key role...the public or private sectors . 3Pub. L. No. 98-525 § 307 (1984). This section was originally codified at 10 U.S.C. § 2304 (note). Letter

  11. Evaluation of Uniform Cost Accounting System to Fully Capture Depot Level Repair Costs.

    Science.gov (United States)

    1985-12-01

    RD-RI65 522 EVALUATION OF UNIFORM COST ACCOUNTING SYSTEM TO FULLY i/I CAPTURE DEPOT LEVEL REPAIR COSTS (U) NAVAL POSTGRADUATE SCHOOL MONTEREY CA D R...8217.LECTE B ,- THESIS EVALUATION OF UNIFORM COST ACCOUNTING SYSTEM 0TO FULLY CAPTURE DEPOT LEVEL REPAIR COSTS Jby __jDavid Richmond O’Brien lj,,, December...Include Security Classification) EVALUATION OF UNIFORM COST ACCOUNTING SYSTEM TO FULLY CAPTURE DEPOT LEVEL REPAIR COSTS 12 PERSONAL AUTHOR(S) O’Brien- David

  12. Enhancement of polycyclic aromatic hydrocarbons in estuarine invertebrates by surface runoff at a decommissioned military fuel depot

    Science.gov (United States)

    Miles, A.K.; Roster, N.

    1999-01-01

    Accumulation of polycyclic aromatic hydrocarbons (PAHs) was determined in blue mussels (Mytilus spp.) and shore crabs (Hemigrapsus sp.) at a recently closed military fuel depot in central San Francisco Bay, California. In April 1996, during a period of above average precipitation, specimens were collected at the depot, near the depot, and at sites 10 and 20 km south of the depot. Four weeks after the rains ended, blue mussels were again collected at the depot, and at two additional sites in the central Bay region. In April, total PAHs in mussels from the depot were significantly higher only than that in mussels collected 20 km from the depot; however, seven specific, substituted PAHs were higher at the depot than at all other sites. In June, only two of the 38 PAHs common in mussels in April were detected at the depot; these concentrations were comparable to ambient concentrations in mussels at the Bay. It seemed that bioavailability of PAHs at the depot was enhanced by rainfall, probably due to the mobilization of PAHs via groundwater into the Bay. Concentrations in mussels from chronically contaminated sites were about five times higher than mussels collected from the depot. Low PAH concentrations were detected in shore crabs near the depot, and the highest levels were not associated with the depot. Observed PAH concentrations are discussed in relation to upper trophic organisms.

  13. Analysis of Tobyhanna Army Depot's Radio Frequency Identification (RFID) Pilot Program: RFID as an Asset Management Tool

    National Research Council Canada - National Science Library

    Miertschin, Keith W; Forrest, Brian D

    2005-01-01

    ...) used for inventory and asset management at the Tobyhanna Army Maintenance Depot. Tobyhanna Army Depot recently partnered with WhereNet Corporation for a pilot program to incorporate a real-time locating system that uses RFID...

  14. Improving Air Force Depot Programming by Linking Resources to Capabilities

    Science.gov (United States)

    2012-01-01

    thank Rick Grisenthwaite at Warner Robins Air Logistics Center, Jamie Jeter at Okla- homa City Air Logistics Center, and Glen Brown at Ogden Air...consistency, we use the term block cycle instead of SCU in our F-16 discussions. 4 8 Im p ro vin g A ir Fo rce D ep o t Pro g ram m in g b y Lin kin...Requirements RAND TR905-B.8 Figure B.9 Depot Purchased Equipment Maintenance Model Output: Projected Aircraft Availability RAND TR905-B.9 A ir cr af t av

  15. Depot Maintenance Air Force Faces Challenges in Managing to 50-50 Ceiling

    National Research Council Canada - National Science Library

    Warren, David

    2000-01-01

    ... that is being moved from the closing Sacramento, California, and San Antonio, Texas, depots to other military depots or private sector sources. As you requested, my testimony today focuses on the basis for the waiver and the likelihood that the Air Force will need additional waivers in the future.

  16. Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue

    NARCIS (Netherlands)

    Gallagher, D.; Kuznia, P.; Heshka, S.; Albu, J.; Heymsfield, S.B.; Goodpaster, B.H.; Visser, M.; Harris, T.B.

    2005-01-01

    BACKGROUND: The manner in which fat depot volumes and distributions, particularly the adipose tissue (AT) between the muscles, vary by race is unknown. OBJECTIVE: The objective was to quantify a previously unstudied and novel intermuscular AT (IMAT) depot and subcutaneous AT, visceral AT (VAT), and

  17. A hybrid metaheuristic algorithm for the multi-depot covering tour vehicle routing problem

    NARCIS (Netherlands)

    Allahyari, S.; Salari, M.; Vigo, D.

    2015-01-01

    We propose a generalization of themulti-depot capacitated vehicle routing problem where the assumption of visiting each customer does not hold. In this problem, called the Multi-Depot Covering Tour Vehicle Routing Problem (MDCTVRP), the demand of each customer could be satisfied in two different

  18. Measuring Customer Satisfaction of Depot Maintenance: An Analysis of Customer Satisfaction of F/A-18 Maintenance at Naval Aviation Depot North Island, CA

    National Research Council Canada - National Science Library

    Forsyth, Brian

    1997-01-01

    .... A key focus of commercial practices is delivering customer satisfaction. To this extent, it is imperative that DoD depots understand and properly measure their customer's concerns if they wish to improve their performance...

  19. Modeling and Solving the Multi-depot Vehicle Routing Problem with Time Window by Considering the Flexible end Depot in Each Route

    Directory of Open Access Journals (Sweden)

    Mohammad Mirabi

    2016-11-01

    Full Text Available This paper considers the multi-depot vehicle routing problem with time window in which each vehicle starts from a depot and there is no need to return to its primary depot after serving customers. The mathematical model which is developed by new approach aims to minimizing the transportation cost including the travelled distance, the latest and the earliest arrival time penalties. Furthermore, in order to reduce the problem searching space, a novel GA clustering method is developed. Finally, Experiments are run on number problems of varying depots and time window, and customer sizes. The method is compared to two other clustering techniques, fuzzy C means (FCM and K-means algorithm. Experimental results show the robustness and effectiveness of the proposed algorithm.

  20. Financial incentives for antipsychotic depot medication: ethical issues.

    Science.gov (United States)

    Claassen, Dirk

    2007-04-01

    Giving money as a direct incentive for patients in exchange for depot medication has proved beneficial in some clinical cases in assertive outreach (AO). However, ethical concerns around this practice have been raised, and will be analysed in more detail here. Ethical concern voiced in a survey of all AO teams in England were analysed regarding their content. These were grouped into categories. 53 of 70 team managers mentioned concerns, many of them serious and expressing a negative attitude towards giving money for depot adherence. Four broad categories of ethical concern following Christensen's concept were distinguished: valid consent and refusal (n = 5), psychiatric paternalism (n = 31), resource allocation (n = 4), organisational relationships (n = 2), with a residual category others and unspecified (n = 11). The main concerns identified are discussed on the background of existing ethical theories in healthcare and the specific problems of community mental health and AO. Points for practice are derived from this discussion. A way forward is outlined that includes informed consent and an operational policy in the use of incentives, further randomised controlled trials and qualitative studies, and continuing discussions with all stakeholders, especially service users.

  1. Artificial immune algorithm for multi-depot vehicle scheduling problems

    Science.gov (United States)

    Wu, Zhongyi; Wang, Donggen; Xia, Linyuan; Chen, Xiaoling

    2008-10-01

    In the fast-developing logistics and supply chain management fields, one of the key problems in the decision support system is that how to arrange, for a lot of customers and suppliers, the supplier-to-customer assignment and produce a detailed supply schedule under a set of constraints. Solutions to the multi-depot vehicle scheduling problems (MDVRP) help in solving this problem in case of transportation applications. The objective of the MDVSP is to minimize the total distance covered by all vehicles, which can be considered as delivery costs or time consumption. The MDVSP is one of nondeterministic polynomial-time hard (NP-hard) problem which cannot be solved to optimality within polynomial bounded computational time. Many different approaches have been developed to tackle MDVSP, such as exact algorithm (EA), one-stage approach (OSA), two-phase heuristic method (TPHM), tabu search algorithm (TSA), genetic algorithm (GA) and hierarchical multiplex structure (HIMS). Most of the methods mentioned above are time consuming and have high risk to result in local optimum. In this paper, a new search algorithm is proposed to solve MDVSP based on Artificial Immune Systems (AIS), which are inspirited by vertebrate immune systems. The proposed AIS algorithm is tested with 30 customers and 6 vehicles located in 3 depots. Experimental results show that the artificial immune system algorithm is an effective and efficient method for solving MDVSP problems.

  2. The Linehaul-Feeder Vehicle Routing Problem with Virtual Depots and Time Windows

    Directory of Open Access Journals (Sweden)

    Huey-Kuo Chen

    2011-01-01

    Full Text Available This paper addresses the linehaul-feeder vehicle routing problem with virtual depots and time windows (LFVRPTW. Small and large vehicles deliver services to customers within time constraints; small vehicles en route may reload commodities from either the physical depot or from the larger vehicle at a virtual depot before continuing onward. A two-stage solution heuristic involving Tabu search is proposed to solve this problem. The test results show that the LFVRPTW performs better than the vehicle routing problem with time windows in terms of both objective value and the number of small vehicles dispatched.

  3. An Analysis of the Cost Accounting System for the Depot Maintenance Service, Air Force Industrial Fund.

    Science.gov (United States)

    1987-09-01

    AN A NALYSIS OF THE COST ACCOUNTING SYSTEM FOR THE DEPOT 1/1 MRINTENANCE SERVI..(U) MIR FORCE INST OF TECH IIGHT-PTTERSON RFB OH SCHOOL OF SYST.. 0 L...I "VV h S~ ~~i FiLE COV, THSI CIO ~OF AN ANALYSIS OF THE COST ACCOUNTING SYSTEM FOR THE DEPOT MAINTENANCE SERVICE, AIR FORCE INDUSTRIAL FUND...Patterson Air Force Base, Ohio ~ p~UOW~~ ’ I ~ 1 12 02 0 AFIT/GLM/LSY/87S-83 AN ANALYSIS OF THE COST ACCOUNTING SYSTEM FOR THE DEPOT MAINTENANCE SERVICE, AIR

  4. Policies for Positioning Empty Containers in an Inland Multi-depot System

    DEFF Research Database (Denmark)

    Dang, Vinh Quang; Nielsen, Izabela Ewa; Yun, Won-Young

    2011-01-01

    -container management are as follows: a coordinated (s, S) inventory policy for overseas positioning, (ri, Ri) policy at each depot for inland positioning; and a simple leasing policy with zero lead-time. For inland positioning policy, four different methods are proposed to reposition empty containers between depots....... Customer demands and returning containers in depots and lead-time for positioning from overseas are considered as uncertain factors. The objective is to obtain the optimal policy in order to minimize the expected total cost including inventory holding, overseas positioning, inland positioning and leasing...

  5. Hotline Allegations Involving Contracts for Programmed Depot Maintenance of KC-135 Aircraft

    National Research Council Canada - National Science Library

    1998-01-01

    Introduction. We performed the audit in response to 15 allegations made to the Defense Hotline involving two contracts on the Programmed Depot Maintenance of the KC-135 Aircraft, which Oklahoma City Air logistics...

  6. Treatment patterns and clinical characteristics prior to initiating depot typical antipsychotics for nonadherent schizophrenia patients

    Directory of Open Access Journals (Sweden)

    Montgomery William

    2009-07-01

    Full Text Available Abstract Background Nonadherence with antipsychotic medication is an important clinical and economic problem in the treatment of schizophrenia. This study identified treatment patterns and clinical characteristics that immediately precede the initiation of depot typical antipsychotics in the usual treatment of schizophrenia patients with a recent history of nonadherence with oral antipsychotic regimens. Methods Data were drawn from a large, multisite, 3-year prospective noninterventional observational study of persons treated for schizophrenia in the United States, which was conducted between 7/1997 and 9/2003. The analytical sample included patients who, in the 6 months prior to enrollment, were considered nonadherent with oral antipsychotics and were not treated with depot antipsychotics (N = 314. Patients who were subsequently initiated on typical depots during the 3-year follow-up were compared with patients who continued therapy with only oral antipsychotic agents. Group comparisons were made on patient baseline characteristics and precedent variables that were assessed 1 to 6 months prior to depot initiation. Patient assessments were made at predetermined intervals throughout the 3-year study using standard psychiatric measures, a patient-reported questionnaire, and medical record information. Results A small proportion of patients (12.4% who were recently nonadherent with oral antipsychotics were subsequently initiated on depot therapy during the 3-year study. Compared to patients treated with only oral antipsychotics, those subsequently initiated on a depot were significantly more likely to be hospitalized at depot initiation or the previous 30 days, to have recent involvement with the criminal justice system (arrests, recent illicit drug use, recent switching or augmentation of oral antipsychotics, and recent treatment with oral typical antipsychotics. Conclusion Despite prior nonadherence with oral antipsychotic medication, only a

  7. Multiple depots vehicle routing based on the ant colony with the genetic algorithm

    Directory of Open Access Journals (Sweden)

    ChunYing Liu

    2013-09-01

    Full Text Available Purpose: the distribution routing plans of multi-depots vehicle scheduling problem will increase exponentially along with the adding of customers. So, it becomes an important studying trend to solve the vehicle scheduling problem with heuristic algorithm. On the basis of building the model of multi-depots vehicle scheduling problem, in order to improve the efficiency of the multiple depots vehicle routing, the paper puts forward a fusion algorithm on multiple depots vehicle routing based on the ant colony algorithm with genetic algorithm. Design/methodology/approach: to achieve this objective, the genetic algorithm optimizes the parameters of the ant colony algorithm. The fusion algorithm on multiple depots vehicle based on the ant colony algorithm with genetic algorithm is proposed. Findings: simulation experiment indicates that the result of the fusion algorithm is more excellent than the other algorithm, and the improved algorithm has better convergence effective and global ability. Research limitations/implications: in this research, there are some assumption that might affect the accuracy of the model such as the pheromone volatile factor, heuristic factor in each period, and the selected multiple depots. These assumptions can be relaxed in future work. Originality/value: In this research, a new method for the multiple depots vehicle routing is proposed. The fusion algorithm eliminate the influence of the selected parameter by optimizing the heuristic factor, evaporation factor, initial pheromone distribute, and have the strong global searching ability. The Ant Colony algorithm imports cross operator and mutation operator for operating the first best solution and the second best solution in every iteration, and reserves the best solution. The cross and mutation operator extend the solution space and improve the convergence effective and the global ability. This research shows that considering both the ant colony and genetic algorithm

  8. Development of self-forming doxorubicin-loaded polymeric depots as an injectable drug delivery system for liver cancer chemotherapy.

    Science.gov (United States)

    Nittayacharn, Pinunta; Nasongkla, Norased

    2017-07-01

    The objective of this work was to develop self-forming doxorubicin-loaded polymeric depots as an injectable drug delivery system for liver cancer chemotherapy and studied the release profiles of doxorubicin (Dox) from different depot formulations. Tri-block copolymers of poly(ε-caprolactone), poly(D,L-lactide) and poly(ethylene glycol) named PLECs were successfully used as a biodegradable material to encapsulate Dox as the injectable local drug delivery system. Depot formation and encapsulation efficiency of these depots were evaluated. Results show that depots could be formed and encapsulate Dox with high drug loading content. For the release study, drug loading content (10, 15 and 20% w/w) and polymer concentration (25, 30, and 35% w/v) were varied. It could be observed that the burst release occurred within 1-2 days and this burst release could be reduced by physical mixing of hydroxypropyl-beta-cyclodextrin (HP-β-CD) into the depot system. The degradation at the surface and cross-section of the depots were examined by Scanning Electron Microscope (SEM). In addition, cytotoxicity of Dox-loaded depots and blank depots were tested against human liver cancer cell lines (HepG2). Dox released from depots significantly exhibited potent cytotoxic effect against HepG2 cell line compared to that of blank depots. Results from this study reveals an important insight in the development of injectable drug delivery system for liver cancer chemotherapy. Schematic diagram of self-forming doxorubicin-loaded polymeric depots as an injectable drug delivery system and in vitro characterizations. (a) Dox-loaded PLEC depots could be formed with more than 90% of sustained-release Dox at 25% polymer concentration and 20% Dox-loading content. The burst release occurred within 1-2 days and could be reduced by physical mixing of hydroxypropyl-beta-cyclodextrin (HP-β-CD) into the depot system. (b) Dox released from depots significantly exhibited potent cytotoxic effect against human

  9. Using the CollaboraKTion framework to report on primary care practice recruitment and data collection: costs and successes in a cross-sectional practice-based survey in British Columbia, Ontario, and Nova Scotia, Canada.

    Science.gov (United States)

    Wong, Sabrina T; Hogg, William; Burge, Fred; Johnston, Sharon; French, Ilisha; Blackman, Stephanie

    2018-06-13

    Across Canada and internationally we have poor infrastructure to regularly collect survey data from primary care practices to supplement data from chart audits and physician billings. The purpose of this work is to: 1) examine the variable costs for carrying out primary care practice-based surveys and 2) share lessons learned about the level of engagement required for recruitment of practices in primary care. This work was part of a larger study, TRANSFORMATION that collected data from three provincial study sites in Canada. We report here on practice-based engagement. Surveys were administered to providers, organizational practice leads, and up to 20 patients from each participating provider. We used the CollaboraKTion framework to report on our recruitment and engagement strategies for the survey work. Data were derived from qualitative sources, including study team meeting minutes, memos/notes from survey administrators regarding their interactions with practice staff, and patients and stakeholder meeting minutes. Quantitative data were derived from spreadsheets tracking numbers for participant eligibility, responses, and completions and from time and cost tracking for patient survey administration. A total of 87 practices participated in the study (n = 22 in BC; n = 26 in ON; n = 39 in NS). The first three of five CollaboraKTion activities, Contacting and Connecting, Deepening Understandings, and Adapting and Applying the Knowledge Base, and their associated processes were most pertinent to our recruitment and data collection. Practice participation rates were low but similar, averaging 36% across study sites, and completion rates were high (99%). Patient completion rates were similarly high (99%), though participation rates in BC were substantially lower than the other sites. Recruitment and data collection costs varied with the cost per practice ranging from $1503 to $1792. A comprehensive data collection system in primary care is possible to achieve with partnerships that balance researcher, clinical, and policy maker contexts. Engaging practices as valued community members and independent business owners requires significant time, and financial and human resources. An integrated knowledge translation and exchange approach provides a foundation for continued dialogue, exchange of ideas, use of the information produced, and recognises recruitment as part of an ongoing cycle.

  10. Performance Gains of Propellant Management Devices for Liquid Hydrogen Depots

    Science.gov (United States)

    Hartwig, Jason W.; McQuillen, John B.; Chato, David J.

    2013-01-01

    This paper presents background, experimental design, and preliminary experimental results for the liquid hydrogen bubble point tests conducted at the Cryogenic Components Cell 7 facility at the NASA Glenn Research Center in Cleveland, Ohio. The purpose of the test series was to investigate the parameters that affect liquid acquisition device (LAD) performance in a liquid hydrogen (LH2) propellant tank, to mitigate risk in the final design of the LAD for the Cryogenic Propellant Storage and Transfer Technology Demonstration Mission, and to provide insight into optimal LAD operation for future LH2 depots. Preliminary test results show an increase in performance and screen retention over the low reference LH2 bubble point value for a 325 2300 screen in three separate ways, thus improving fundamental LH2 LAD performance. By using a finer mesh screen, operating at a colder liquid temperature, and pressurizing with a noncondensible pressurant gas, a significant increase in margin is achieved in bubble point pressure for LH2 screen channel LADs.

  11. ATTITUDES OF SHOP FLOOR EMPLOYEES TOWARD WOMEN MANAGERS IN FUEL DEPOTS: A CASE OF THE FUEL DEPOTS IN LUBUMBASHI, DEMOCRATIC REPUBLIC OF THE CONGO

    Directory of Open Access Journals (Sweden)

    Stephen N. M. Nzuve

    2014-12-01

    Full Text Available The International Labour Organization and all organizations of human rights advocate against any form of negative attitude in employment based on gender, its terms, promotion and relations. Shop floor employees play a very important role in the daily advancement and profitability of an organisation. The purpose of this study was to establish the attitude of shop floor employees toward women managers in fuel depots in Lubumbashi, Democratic Republic of the Congo. The study adopted a descriptive survey design with the population consisting of one hundred and ninety three (193 shop floor employees. A semi structured questionnaire was used to collect primary data. In total one hundred and twenty one (121 shop floor employees responded yielding a response rate of sixty three percent (63%. The findings of this study indicate that a negative attitude toward woman managers is prevalent in the Fuel Depots of Lubumbashi, Democratic Republic of the Congo. At the fuel depots, the number of women working was less than a third of the males. In spite of this, women managers are rated higher in management qualities and are considered to be more honest, diligent, compassionate, creative and intelligent when compared to their male counterparts. The study recommends a culture change among employees in fuel depots in Lubumbashi in order to enable them perceive women as equal partners at the work place.

  12. Measurement of ground and nearby building vibration and noise induced by trains in a metro depot.

    Science.gov (United States)

    Zou, Chao; Wang, Yimin; Wang, Peng; Guo, Jixing

    2015-12-01

    Metro depots are where subway trains are parked and where maintenance is carried out. They usually occupy the largest ground areas in metro projects. Due to land utilization problems, Chinese cities have begun to develop over-track buildings above metro depots for people's life and work. The frequently moving trains, when going into and out of metro depots, can cause excessive vibration and noise to over-track buildings and adversely affect the living quality of the building occupants. Considering the current need of reliable experimental data for the construction of metro depots, field measurements of vibration and noise on the ground and inside a nearby 3-story building subjected to moving subway trains were conducted in a metro depot at Guangzhou, China. The amplitudes and frequency contents of velocity levels were quantified and compared. The composite A-weighted equivalent sound levels and maximum sound levels were captured. The predicted models for vibration and noise of metro depot were proposed based on existing models and verified. It was found that the vertical vibrations were significantly greater than the horizontal vibrations on the ground and inside the building near the testing line. While at the throat area, the horizontal vibrations near the curved track were remarkably greater than the vertical vibrations. The attenuation of the vibrations with frequencies above 50 Hz was larger than the ones below 50 Hz, and the frequencies of vibration transmitting to adjacent buildings were mainly within 10-50 Hz. The largest equivalent sound level generated in the throat area was smaller than the testing line one, but the instantaneous maximum sound level induced by wheels squeal, contact between wheels and rail joints as well as turnout was close to or even greater than the testing line one. The predicted models gave a first estimation for design and assessment of newly built metro depots. Copyright © 2015 Elsevier B.V. All rights reserved.

  13. Depo-Provera (depot medroxyprogesterone acetate) use after bariatric surgery.

    Science.gov (United States)

    Lam, Clarissa; Murthy, Amitasrigowri S

    2016-01-01

    In the US, obesity rates are increasing greatly. The Centers for Disease Control and Prevention estimates that 68.5% of Americans, including 63.9% of adult women older than 20 years, are overweight (body mass index between 25 kg/m 2 and 29.9 kg/m 2 ) or obese (body mass index >30 kg/m 2 ). In light of this, it is not surprising that the rates of bariatric surgery have also been increasing. When considering the metabolic changes associated with both bariatric surgery and contraceptive use, in combination with the unique medical considerations of obese women, it is indisputable that clear guidelines are needed when counseling obese patients of reproductive age after bariatric surgery. In this literature review, we focus on depot medroxyprogesterone acetate (DMPA) and the implications of its use in obese women, preweight and postweight loss following bariatric surgery. Both DMPA use and bariatric surgery are known to cause bone loss, but it is still unclear whether there is an additive effect of the two factors on bone loss and whether either of these factors directly leads to an increased risk of bone fracture. The current consensus guidelines do not impose a restriction on the use of DMPA after bariatric surgery. DMPA use is associated with weight gain, and it is unclear whether weight loss blunting occurs with the use of DMPA after bariatric surgery. Prior studies had demonstrated an association with weight gain in adolescents, and therefore, those prescribing DMPA use after bariatric surgery in adolescents should proceed with caution. Adult women do not have a similar response to the use of DMPA. DMPA use has rarely been associated with increased risk of venous thromboembolism (VTE). The obesity-associated increase in VTE should be mitigated by surgically induced weight loss. The concurrent use of DMPA in the post bariatric surgical period should not further increase the risk of VTE.

  14. Artificial intelligence technology assessment for the US Army Depot System Command

    Energy Technology Data Exchange (ETDEWEB)

    Pennock, K A

    1991-07-01

    This assessment of artificial intelligence (AI) has been prepared for the US Army's Depot System Command (DESCOM) by Pacific Northwest Laboratory. The report describes several of the more promising AI technologies, focusing primarily on knowledge-based systems because they have been more successful in commercial applications than any other AI technique. The report also identifies potential Depot applications in the areas of procedural support, scheduling and planning, automated inspection, training, diagnostics, and robotic systems. One of the principal objectives of the report is to help decisionmakers within DESCOM to evaluate AI as a possible tool for solving individual depot problems. The report identifies a number of factors that should be considered in such evaluations. 22 refs.

  15. Preparation and in vitro characterization of SN-38-loaded, self-forming polymeric depots as an injectable drug delivery system.

    Science.gov (United States)

    Manaspon, Chawan; Hongeng, Suradej; Boongird, Atthaporn; Nasongkla, Norased

    2012-10-01

    This work describes the preparation and characterization of anticancer-loaded injectable polymeric depots that consisted of D,L-lactide (LA), ε-caprolactone (CL), and poly(ethylene glycol) (PEG) or [poly(ε-caprolactone)-random-poly(D,L-lactide)]-block-poly(ethylene glycol)-block-[poly(ε-caprolactone)-random-poly(D,L-lactide)] (PLEC) copolymers for malignant gliomas treatment. PLECs were polymerized with different percentages of LA to deliver 7-ethyl-10-hydroxycamptothecin (SN-38), a highly potent anticancer drug. SN-38-loaded depots could form directly in phosphate buffer saline with more than 98% encapsulation efficiency. The release rate of SN-38 from depots was found to depend on the amount of LA in PLECs, loading content of SN-38 in the depots, and depot weight. Encapsulation of SN-38 inside depots could enhance the stability of SN-38 where all of SN-38 released after 60 days was in an active form. Depots without SN-38 were evaluated as noncytotoxic against U-87MG, whereas SN-38-loaded depots showed cytotoxic effect as a function of concentration. Copyright © 2012 Wiley Periodicals, Inc.

  16. Male bovine GH transgenic mice have decreased adiposity with an adipose depot-specific increase in immune cell populations.

    Science.gov (United States)

    Benencia, Fabian; Harshman, Stephanie; Duran-Ortiz, Silvana; Lubbers, Ellen R; List, Edward O; Householder, Lara; Al-Naeeli, Mawadda; Liang, Xiaoyu; Welch, Lonnie; Kopchick, John J; Berryman, Darlene E

    2015-05-01

    White adipose tissue (WAT) is composed of mature adipocytes and a stromal vascular fraction (SVF), which contains a variety of cells, including immune cells that vary among the different WAT depots. Growth hormone (GH) impacts immune function and adiposity in an adipose depot-specific manner. However, its effects on WAT immune cell populations remain unstudied. Bovine GH transgenic (bGH) mice are commonly used to study the in vivo effects of GH. These giant mice have an excess of GH action, impaired glucose metabolism, decreased adiposity, increased lean mass, and a shortened lifespan. Therefore, the purpose of this study was to characterize the WAT depot-specific differences in immune cell populations in the presence of excess GH in vivo. Three WAT depots were assessed: inguinal (sc), epididymal (EPI), and mesenteric (MES). Subcutaneous and MES bGH WAT depots showed a significantly higher number of total SVF cells, yet only MES bGH WAT had higher leukocyte counts compared with control samples. By means of flow cytometry analysis of the SVF, we detected greater macrophage and regulatory T-cell infiltration in sc and MES bGH WAT depots compared with controls. However, no differences were observed in the EPI WAT depot. RNA-sequencing confirmed significant alterations in pathways related to T-cell infiltration and activation in the sc depot with fewer significant changes in the EPI bGH WAT depot. These findings collectively point to a previously unrecognized role for GH in influencing the distribution of WAT immune cell populations in a depot-specific manner.

  17. Depo-Provera (depot medroxyprogesterone acetate use after bariatric surgery

    Directory of Open Access Journals (Sweden)

    Lam C

    2016-09-01

    Full Text Available Clarissa Lam,1 Amitasrigowri S Murthy2,3 1New York University School of Medicine, 2Department of Obstetrics and Gynecology, Bellevue Hospital Center, New York University School of Medicine, 3New York University Langone Medical Center, New York, NY, USA Abstract: In the US, obesity rates are increasing greatly. The Centers for Disease Control and Prevention estimates that 68.5% of Americans, including 63.9% of adult women older than 20 years, are overweight (body mass index between 25 kg/m2 and 29.9 kg/m2 or obese (body mass index >30 kg/m2. In light of this, it is not surprising that the rates of bariatric surgery have also been increasing. When considering the metabolic changes associated with both bariatric surgery and contraceptive use, in combination with the unique medical considerations of obese women, it is indisputable that clear guidelines are needed when counseling obese patients of reproductive age after bariatric surgery. In this literature review, we focus on depot medroxyprogesterone acetate (DMPA and the implications of its use in obese women, preweight and postweight loss following bariatric surgery. Both DMPA use and bariatric surgery are known to cause bone loss, but it is still unclear whether there is an additive effect of the two factors on bone loss and whether either of these factors directly leads to an increased risk of bone fracture. The current consensus guidelines do not impose a restriction on the use of DMPA after bariatric surgery. DMPA use is associated with weight gain, and it is unclear whether weight loss blunting occurs with the use of DMPA after bariatric surgery. Prior studies had demonstrated an association with weight gain in adolescents, and therefore, those prescribing DMPA use after bariatric surgery in adolescents should proceed with caution. Adult women do not have a similar response to the use of DMPA. DMPA use has rarely been associated with increased risk of venous thromboembolism (VTE. The

  18. Clinical outcome of one-third-dose depot triptorelin is the same as half-dose depot triptorelin in the long protocol of controlled ovarian stimulation

    Directory of Open Access Journals (Sweden)

    Yu Li

    2012-01-01

    Full Text Available Objective: Appropriate dosage of the long-acting depot gonadotrophin releasing hormone (GnRH agonist has not been determined in long protocol for IVF, and one-third-dose depot triptorelin was compared with half-dose in a luteal long protocol of in-vitro fertilization/ intra cytoplasmic sperm injection (IVF/ICSI treatment in this study. Materials and Methods: This is a prospective, randomized, open clinical trial. 100 patients were randomized into two groups. Group I received one-third-dose (1.25 mg depot triptorelin. Group II received half-dose (1.87 mg. The clinical and experimental parameters were compared between the two groups. Results: There was no premature luteinizing hormone (LH surge in both groups. On Day 3-5 of menstrual cycle after down-regulation, fewer patients showed low-level LH (<1.0 IU/L and estradiol (<30 pg/mL in group I (P <0.05. There were fewer oocytes retrieved (P =0.086, fewer total embryos and available embryos for cryopreservation in Group I (P <0.05, while good-quality embryo rate was higher in group I (P <0.05. The length and dose of ovarian stimulation was lower in Group I, but not significantly. The clinical pregnancy (52% versus 40%, implantation (48% versus 37.5%, delivery (46% versus 32%, or live birth (42% versus 32% rates and the abortion (8% versus 20% rates showed no significant differences. Conclusion: Depot triptorelin 1.25 mg can be successfully used with reduced pituitary suppression and lower cost in a long protocol for in-vitro fertilization.

  19. Multicenter clinical trial of leuprolide acetate depot (Luphere depot 3.75 mg for efficacy and safety in girls with central precocious puberty

    Directory of Open Access Journals (Sweden)

    You Jin Kim

    2013-12-01

    Full Text Available PurposeWe evaluated the efficacy, safety and psychological aspect of monthly administrations of the gonadotropin-releasing hormone agonists (GnRHa, leuprolide acetate depot (Luphere depot 3.75 mg, in patients with precocious puberty.MethodsA total of 54 girls with central precocious puberty were administered with leuprolide acetate (Luphere depot 3.75 mg every four weeks over 24 weeks. We evaluated the percentage of children exhibiting a suppressed luteinizing hormone (LH response to GnRH (LH peak≤3 IU/L, peak LH/follicle stimulating hormone (FSH ratio of GnRH stimulation test less than 1, change in bone age/chronologic age ratio, change in the Tanner stage and change in eating habit and psychological aspect.Results(1 The percentage of children exhibiting a suppressed LH response to GnRH, defined as an LH peak≤3 IU/L at 24 weeks was 96.3 % (52/54. (2 The percentage of children exhibiting peak LH/FSH ratio<1 at 24 weeks of the study was 94.4 % (51/54. (3 The ratio of bone age and chronological age significantly declined from 1.27±0.07 to 1.24±0.01 after the 6 months of the study. (4 The mean Tanner stage manifested a significant change 2.3±0.48 at baseline, down to 1.70±0.61 at 24 weeks. (5 Based on the questionnaires, the score for eating habits showed a significant change from the baseline 34.0±6.8 to 31.3±6.8. (6 The psychological assessment did not exhibit a significant difference except with scores for sociability, problem behavior total score and other problems.ConclusionThe leuprolide 3.75 mg (Luphere depot is useful and safety for treating children with central precocious puberty.

  20. Inflammation and race and gender differences in computerized tomography-measured adipose depots

    NARCIS (Netherlands)

    Beasley, L.E.; Koster, A.; Newman, A.B.; Javaid, M.K.; Ferucci, L.; Kritchevsky, S.B.; Kuller, L.H.; Pahor, M.; Visser, M.; Rubin, S.M.; Goodpaster, B.H.; Everhart, J.E.; Harris, T.B.

    2009-01-01

    A growing body of evidence has consistently shown a correlation between obesity and chronic subclinical inflammation. It is unclear whether the size of specific adipose depots is more closely associated with concentrations of inflammatory markers than overall adiposity. This study investigated the

  1. Clay Nanoparticles Elicit Long-Term Immune Responses by Forming Biodegradable Depots for Sustained Antigen Stimulation.

    Science.gov (United States)

    Chen, Weiyu; Zuo, Huali; Li, Bei; Duan, Chengcheng; Rolfe, Barbara; Zhang, Bing; Mahony, Timothy J; Xu, Zhi Ping

    2018-05-01

    Nanomaterials have been widely tested as new generation vaccine adjuvants, but few evoke efficient immunoreactions. Clay nanoparticles, for example, layered double hydroxide (LDH) and hectorite (HEC) nanoparticles, have shown their potent adjuvanticity in generating effective and durable immune responses. However, the mechanism by which clay nanoadjuvants stimulate the immune system is not well understood. Here, it is demonstrated that LDH and HEC-antigen complexes form loose agglomerates in culture medium/serum. They also form nodules with loose structures in tissue after subcutaneous injection, where they act as a depot for up to 35 d. More importantly, clay nanoparticles actively and continuously recruit immune cells into the depot for up to one month, and stimulate stronger immune responses than FDA-approved adjuvants, Alum and QuilA. Sustained antigen release is also observed in clay nanoparticle depots, with 50-60% antigen released after 35 d. In contrast, Alum-antigen complexes show minimal antigen release from the depot. Importantly, LDH and HEC are more effective than QuilA and Alum in promoting memory T-cell proliferation. These findings suggest that both clay nanoadjuvants can serve as active vaccine platforms for sustained and potent immune responses. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Pharmacodynamic effects of depot-medroxyprogesterone acetate (DMPA) administered to lactating women on their male infants

    NARCIS (Netherlands)

    Virutamasen, P; Leepipatpaiboon, S; Kriengsinyot, R; Vichaidith, P; Muia, PN; SekaddeKigondu, CB; Mati, JKG; Forest, MG; Dikkeschei, LD; Wolthers, BG; dArcangues, C

    Normal postpartum women, who had a spontaneous vaginal delivery of one full-term male infant, free of congenital abnormalities and other diseases, were recruited for this study. Thirteen women received 150 mg depot-medroxyprogesterone acetate (DMPA), intramuscularly on days 42 + 1 and 126 + 1

  3. Verspreiding van zout bij het terugwinnen van zeezand uit een depot in het Haringvliet

    NARCIS (Netherlands)

    Kranenburg, C.

    1991-01-01

    Dit rapport geeft een beknopte analyse van de verdunning en verspreiding van zout vanuit een gepland depot voor ontzilt zeezand in het Haringvliet. Beschouwd zijn de initiële menging van het zout bij terugwinnen van het zand, de verspreiding door stroming en turbulentie bij geopende spuisluis, en de

  4. Safety Extension Study Of Leuprolide Acetate (Lupron Depot) In The Treatment Of Central Precocious Puberty

    Science.gov (United States)

    2014-01-08

    Precocious; Leuprolide Acetate; Luteinizing Hormone (LH); Gonadotrophin-releasing Hormone Agonist (GnRHa); Tanner Staging; Depot Formulation; Suppression of LH; Central Precocious Puberty (CPP); Gonadotrophin-releasing Hormone (GnRH); Lupron; GnRH Analog; Pediatrics Central Precocious Puberty

  5. Sustained release of antibiotics from injectable and thermally responsive polypeptide depots.

    Science.gov (United States)

    Adams, Samuel B; Shamji, Mohammed F; Nettles, Dana L; Hwang, Priscilla; Setton, Lori A

    2009-07-01

    Biodegradable polymeric scaffolds are of interest for delivering antibiotics to local sites of infection in orthopaedic applications, such as bone and diarthrodial joints. The objective of this study was to develop a biodegradable scaffold with ease of drug loading in aqueous solution, while providing for drug depot delivery via syringe injection. Elastin-like polypeptides (ELPs) were used for this application, biopolymers of repeating pentapeptide sequences that were thermally triggered to undergo in situ depot formation at body temperature. ELPs were modified to enable loading with the antibiotics, cefazolin, and vancomycin, followed by induction of the phase transition in vitro. Cefazolin and vancomycin concentrations were monitored, as well as bioactivity of the released antibiotics, to test an ability of the ELP depot to provide for prolonged release of bioactive drugs. Further tests of formulation viscosity were conducted to test suitability as an injectable drug carrier. Results demonstrate sustained release of therapeutic concentrations of bioactive antibiotics by the ELP, with first-order time constants for drug release of approximately 25 h for cefazolin and approximately 500 h for vancomycin. These findings illustrate that an injectable, in situ forming ELP depot can provide for sustained release of antibiotics with an effect that varies across antibiotic formulation. ELPs have important advantages for drug delivery, as they are known to be biocompatible, biodegradable, and elicit no known immune response. These benefits suggest distinct advantages over currently used carriers for antibiotic drug delivery in orthopedic applications. (c) 2008 Wiley Periodicals, Inc.

  6. The contribution of the in-vivo fate of an oil depot to drug absorption

    NARCIS (Netherlands)

    Kalicharan, R. W.; Oussoren, C; Schot, Peter; Rijk, de, E.; Vromans, H.

    2017-01-01

    Sustained release of lipophilic compounds can be achieved with oil depots. These parenteral formulations are generally injected in the vastus lateralis and deltoid muscle. It is known that the absorption rate differs between these two muscles. The reason for this is not fully understood. The aim of

  7. Field Demonstration/Validation of Electrolytic Barriers for Energetic Compounds at Pueblo Chemical Depot

    Science.gov (United States)

    2010-01-01

    measuring the intensity of fluorescence at 517 nm using an Ocean Optics USB-2000TM spectrometer and an Ocean OpticsTM custom six-around-one fiber ...Umatilla Army Depot, OR Demilitarization (washout) Basalt Deep (>50 feet) NRC (2005) Installation Action Plan for UAAP March 2001 Hawthorne

  8. Implementation of Geographical Information System for Bacteriological Contamination Analysis on Refill Drinking Water Depot (Study in Tembalang District)

    Science.gov (United States)

    Rahmitha, Amelia; Utami, Endang Sri; Sitohang, Marya Yenita

    2018-02-01

    People used refilled-drinking-water for household and food stall because its efficient and low cost. Based on Indonesian Health Ministry regulation, it should not have any coliform bacteria. This study aimed to describe the bacteriological contamination of refilled drinking water using geographical information system (GIS). In this research, it was used an analytic observational method. The samples were from all available (37) depots in Tembalang district, one form each depot took used a sterile bottle. Contamination of bacteria was identified by Most Probable Number (MPN) method lactose broth media, Mac Conkey media, and IMVIC media. The depot samples were then plotted on (GIS). This study showed 95% samples were not feasible to consume since they contamined coliform. All sub-district had one that contaminated by coliform, 75% sub-districts had depots that contaminated Escherichia coli, while 55% sub-districts had depots that contaminated with other bacteria. The internal risk factors of the contamination were the absence of hygiene-sanitation worthy certificate (95%), depots location near to pollution sources (5%), and the misused of UV light. The external risk factor was lack of quality control that was not as the sterilization from office health Semarang city. Policy reinforcement should be done to all of the depots.

  9. Cost-Utility Analysis of Depot Atypical Antipsychotics for Chronic Schizophrenia in Croatia.

    Science.gov (United States)

    Jukic, Vlado; Jakovljevic, Miro; Filipcic, Igor; Herceg, Miroslav; Silic, Ante; Tomljanovic, Tatjana; Zilbershtein, Roman; Jensen, Rasmus C D; Hemels, Michiel E H; Einarson, Thomas R

    As a nation with a developing economy, Croatia is faced with making choices between pharmaceutical products, including depot injectable antipsychotics. We conducted a pharmacoeconomic analysis to determine the cost-effectiveness of atypical depots in Croatia. A 1-year decision-analytic framework modeled drug use. We determined the average direct cost to the Croatian Institute for Health Insurance of using depot formulations of paliperidone palmitate long-acting injectable (PP-LAI), risperidone LAI (RIS-LAI), or olanzapine LAI (OLZ-LAI). An expert panel plus literature-derived clinical rates populated the core model, along with costs adjusted to 2012 by using the Croatian consumer price index. Clinical outcomes included quality-adjusted life-years, hospitalization rates, emergency room treatment rates, and relapse days. Robustness of results was examined with one-way sensitivity analyses on important inputs; overall, all inputs were varied over 10,000 simulations in a Monte Carlo analysis. Costs (quality-adjusted life-years) per patient were €5061 (0.817) for PP-LAI, €5168 (0.807) for RIS-LAI, and €6410 (0.812) for OLZ-LAI. PP-LAI had the fewest relapse days, emergency room visits, and hospitalizations. Results were sensitive against RIS-LAI with respect to drug costs and adherence rates, but were generally robust overall, dominating OLZ-LAI in 77.3% and RIS-LAI in 56.8% of the simulations. PP-LAI dominated the other drugs because it had the lowest cost and best clinical outcomes. Compared with depots of olanzapine and risperidone and oral olanzapine, PP-LAI was the cost-effective atypical LAI for treating chronic schizophrenia in Croatia. Using depot paliperidone in place of either olanzapine or risperidone would reduce the overall costs of caring for these patients. Copyright © 2013, International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc.

  10. Hypoxia induced VEGF synthesis in visceral adipose depots of obese diabetic patients.

    Science.gov (United States)

    Fusaru, Ana Marina; Pisoschi, Cătălina Gabriela; Bold, Adriana; Taisescu, C; Stănescu, R; Hîncu, Mihaela; Crăiţoiu, Stefania; Baniţă, Ileana Monica

    2012-01-01

    VEGF is one the pro-inflammatory adipokines synthesized by the "adipose secretoma" of obese subjects as a response to hypoxic conditions; but the main function of VEGF is angiogenesis, being recognized as the most important factor increasing blood capillaries in the adipose tissue by stimulating endothelial cell growth. In this paper, we propose a comparative study of the vascular response to VEGF synthesis in the subcutaneous and central-peritoneal adipose depots in lean, obese and obese diabetic patients. We used CD31 to label the endothelial cells in order to evaluate the response of the vascular network to VEGF synthesis. Our results showed an increase of VEGF protein synthesis in obese and obese-diabetic patients compared to lean subjects where the protein was absent. The positivity for VEGF in obese diabetic samples was observed in numerous structures from the adipose depots, both in the stromal vascular fraction--blood vessels and stromal cells--as well as in the cytoplasm of adipocytes. Positivity in the vascular wall was observed more frequently in areas of perivascular and intralobular fibrosis. Obese and diabetic patients showed similar incidence of CD31 immunoreactivity with lean subjects in both subcutaneous and peritoneal depots. In conclusion, human adipose depots show a different incidence of VEGF positive cells in relation with their disposal and the metabolic status. VEGF synthesis in visceral adipose tissue is inefficient being not followed by angiogenesis to counterbalance tissue hypoxia. We suggest that may be a pathogenic link between the degrees of intralobular fibrosis in adipose depots and VEGF expression.

  11. RATIONAL RECOVERY MODEL OF DEPOT PROCESSING EQUIPMENT AT THE INDUSTRIAL ENTERPRISE

    Directory of Open Access Journals (Sweden)

    M. I. Kapitsa

    2014-07-01

    Full Text Available Purpose. The problem of the maximum resources recovery of rolling stock repair depot of industrial enterprise with limited resources consumption, which are used in the system is today’s topical question.The main factors that affect the repair depot operation of industrial enterprise are reviewed. The most significant factors, affecting the quality of the repair depot, are emphasized for further study, specifically - the state of the major repair equipment of a sector. There is a need to minimize the impact of the unsatisfactory state of this factor. Methodology. The formed task of major equipment rational repairing in the mathematical sense is based on the solution of a vector optimization problem. In this case the target functions are the monetary funds spending and time expenditure for repairing. Findings. The mathematical model of optimal equipment maintainability of the repair department at the industrial enterprise was developed by the authors. On the example the choice model of optimal path for equipment repairing of enterprise repair department is described. Originality. As a result of the conducted research the repairing system of major equipment of industrial enterprise sectors was improved. As the mathematical model of rational system recovery of industrial enterprise repair depot we recommend apparatus of class problems of vector optimization. Practical value. Using the proposed model of major equipment repair system of the repair depot at the industrial enterprise will improve the quality of the department by increasing the efficiency of primary resources - time and monetary funds - which are spent by the sector in order to repair its techniques.

  12. Pengaruh Kepuasan Dan Kepercayaan Terhadap Keputusan Pembelian Ulang Pada Depot Air Minum Tris Water Reverse Osmosis System (Ro)

    OpenAIRE

    Fitria, Ika

    2011-01-01

    Kind of this survey is asociative survey which watch influence of customer satisfaction and trust to re-purchase decision on Depot Air Minum Tris Water Reverse Osmosis System (RO) and test of hypothesis use Multiple Linear Regression Analysist on α=5%. This survey used SPSS 16.00 version for windows. Research population is consumers of Depot Air Minum Tris Water Reverse Osmosis System (RO). Sample was used in this survey from customers of Depot Air Minum Tris Water Reverse Osmosis System (RO)...

  13. Experiences gained in the conditioning of radioactive wastes from regional depots by example of Kernforschungszentrum Karlsruhe, and recommendations for the establishment of regional depots in the new Federal States of unified Germany

    International Nuclear Information System (INIS)

    Pfeifer, W.

    1992-01-01

    Details are given about radioactive waste management and radioactive waste management fundamentals as well as about the respective methods applied by the Baden-Wuerttemberg radioacive waste depot. The waste treatment, quality assurance and internal inspection methods applied by Hauptabteilung Dekontaminationsbetriebe (HDB), Kernforschungszentrum Karlsruhe (KfK) are described, and recommendations are given for the establishment of regional depots in the new provinces of the Federal Republic of Germany. These recommendations which are based on Western German standards before unification suggest regional depots with combined administrative systems which watch over the depot use and charges, the foundation of a waste management association responsible for the disposal, transport, intermediate storage and conditioning of radioactive wastes in the new provinces, and the establishment of a facility to be run by the proposed waste management association for the intermediate storage of conditioned waste packages intended for final disposal. (orig.) [de

  14. Maternal obesity programs increased leptin gene expression in rat male offspring via epigenetic modifications in a depot-specific manner

    Directory of Open Access Journals (Sweden)

    Simon Lecoutre

    2017-08-01

    Conclusions: Consistent with the DOHaD hypothesis, persistent epigenetic remodeling occurs at regulatory regions especially within intergenic sequences, linked to higher leptin gene expression in adult HF offspring in a depot-specific manner.

  15. Financial Reporting Procedures for Defense Distribution Depots - Defense Logistics Agency Business Area of the Defense Business Operations Fund

    National Research Council Canada - National Science Library

    Young, Shelton

    1994-01-01

    In our audit of the FY 1993 Financial Statements for the Distribution Depots--Defense Logistics Agency Business Mea of the Defense Business Operations Fund, we evaluated procedures and controls used...

  16. Examining a Paradigm Shift in Organic Depot-Level Software Maintenance for Army Communications and Electronics Equipment

    Science.gov (United States)

    2015-05-30

    scalable application of cutting edge technologies. 20 4. Responding to changing resources—With likely significant resource reductions the depot...deal with underutilized organic capability while continuing to increase outsourcing of depot workload. In addition the study states that a...the unique organic skills that TYAD could 40 bring to the software sustainment mission could be valuable based on the specific type of software

  17. Depot-medication compliance for patients with psychotic disorders: the importance of illness insight and treatment motivation.

    Science.gov (United States)

    Noordraven, Ernst L; Wierdsma, André I; Blanken, Peter; Bloemendaal, Anthony Ft; Mulder, Cornelis L

    2016-01-01

    Noncompliance is a major problem for patients with a psychotic disorder. Two important risk factors for noncompliance that have a severe negative impact on treatment outcomes are impaired illness insight and lack of motivation. Our cross-sectional study explored how they are related to each other and their compliance with depot medication. Interviews were conducted in 169 outpatients with a psychotic disorder taking depot medication. Four patient groups were defined based on low or high illness insight and on low or high motivation. The associations between depot-medication compliance, motivation, and insight were illustrated using generalized linear models. Generalized linear model showed a significant interaction effect between motivation and insight. Patients with poor insight and high motivation for treatment were more compliant (94%) (95% confidence interval [CI]: 1.821, 3.489) with their depot medication than patients with poor insight and low motivation (61%) (95% CI: 0.288, 0.615). Patients with both insight and high motivation for treatment were less compliant (73%) (95% CI: 0.719, 1.315) than those with poor insight and high motivation. Motivation for treatment was more strongly associated with depot-medication compliance than with illness insight. Being motivated to take medication, whether to get better or for other reasons, may be a more important factor than having illness insight in terms of improving depot-medication compliance. Possible implications for clinical practice are discussed.

  18. Intrinsic differences in adipocyte precursor cells from different white fat depots

    DEFF Research Database (Denmark)

    Macotela, Yazmín; Emanuelli, Brice; Mori, Marcelo A

    2012-01-01

    Obesity and body fat distribution are important risk factors for the development of type 2 diabetes and metabolic syndrome. Evidence has accumulated that this risk is related to intrinsic differences in behavior of adipocytes in different fat depots. In the current study, we demonstrate...... that adipocyte precursor cells (APCs) isolated from visceral and subcutaneous white adipose depots of mice have distinct patterns of gene expression, differentiation potential, and response to environmental and genetic influences. APCs derived from subcutaneous fat differentiate well in the presence of classical...... induction cocktail, whereas those from visceral fat differentiate poorly but can be induced to differentiate by addition of bone morphogenetic protein (BMP)-2 or BMP-4. This difference correlates with major differences in gene expression signature between subcutaneous and visceral APCs. The number of APCs...

  19. Understanding of empty container movement: A study on a bottleneck at an off-dock depot

    Science.gov (United States)

    Zain, Rosmaizura Mohd; Rahman, Mohd Nizam Ab; Nopiah, Zulkifli Mohd; Saibani, Nizaroyani

    2014-09-01

    Port not only function as connections between marine and land transportation but also as core business areas. In a port terminal, available space is limited, but the influx of container is growing. The off-dock depot is one of the key supply chain players that hold empty containers in the inventory. Therefore, this paper aims to identify the main factors of bottlenecks or congestion that hinder the rapid movement of empty containers from the off-dock depot to the customers. Thirty interviews were conducted with individuals who are key players in the container supply chain. The data were analyzed using Atlas.ti software and the analytic hierarchy process to rank the priority factors of bottlenecks. Findings show that several pertinent factors act as barriers to the key players in the container movement in the day-to-day operations. In future studies, strategies to overcome fragmentation in the container supply chain and logistics must be determined.

  20. Optimizing the Shunting Schedule of Electric Multiple Units Depot Using an Enhanced Particle Swarm Optimization Algorithm

    Directory of Open Access Journals (Sweden)

    Jiaxi Wang

    2016-01-01

    Full Text Available The shunting schedule of electric multiple units depot (SSED is one of the essential plans for high-speed train maintenance activities. This paper presents a 0-1 programming model to address the problem of determining an optimal SSED through automatic computing. The objective of the model is to minimize the number of shunting movements and the constraints include track occupation conflicts, shunting routes conflicts, time durations of maintenance processes, and shunting running time. An enhanced particle swarm optimization (EPSO algorithm is proposed to solve the optimization problem. Finally, an empirical study from Shanghai South EMU Depot is carried out to illustrate the model and EPSO algorithm. The optimization results indicate that the proposed method is valid for the SSED problem and that the EPSO algorithm outperforms the traditional PSO algorithm on the aspect of optimality.

  1. Optimizing the Shunting Schedule of Electric Multiple Units Depot Using an Enhanced Particle Swarm Optimization Algorithm

    Science.gov (United States)

    Jin, Junchen

    2016-01-01

    The shunting schedule of electric multiple units depot (SSED) is one of the essential plans for high-speed train maintenance activities. This paper presents a 0-1 programming model to address the problem of determining an optimal SSED through automatic computing. The objective of the model is to minimize the number of shunting movements and the constraints include track occupation conflicts, shunting routes conflicts, time durations of maintenance processes, and shunting running time. An enhanced particle swarm optimization (EPSO) algorithm is proposed to solve the optimization problem. Finally, an empirical study from Shanghai South EMU Depot is carried out to illustrate the model and EPSO algorithm. The optimization results indicate that the proposed method is valid for the SSED problem and that the EPSO algorithm outperforms the traditional PSO algorithm on the aspect of optimality. PMID:27436998

  2. On the multiple depots vehicle routing problem with heterogeneous fleet capacity and velocity

    Science.gov (United States)

    Hanum, F.; Hartono, A. P.; Bakhtiar, T.

    2018-03-01

    This current manuscript concerns with the optimization problem arising in a route determination of products distribution. The problem is formulated in the form of multiple depots and time windowed vehicle routing problem with heterogeneous capacity and velocity of fleet. Model includes a number of constraints such as route continuity, multiple depots availability and serving time in addition to generic constraints. In dealing with the unique feature of heterogeneous velocity, we generate a number of velocity profiles along the road segments, which then converted into traveling-time tables. An illustrative example of rice distribution among villages by bureau of logistics is provided. Exact approach is utilized to determine the optimal solution in term of vehicle routes and starting time of service.

  3. Formative Evaluation of a Sociotechnical System Intervention at an Army Maintenance Depot

    Science.gov (United States)

    1986-07-01

    periodically reassess itself to determine if the balance between the technical and social systems remains adaptive and responsive to the requirements...developed a comprehensive set of recommendations for improving the balance between the social and technical systems of the depot. During 1983, most of...ity and quality of worklife . However, the nature and extent of the impact is highly elusive and resistant to quantification. 1-4 FORMATIVE

  4. DoD Depot-Level Reparable Supply Chain Management: Process Effectiveness and Opportunities for Improvement

    Science.gov (United States)

    2014-01-01

    Parts MIS Materiel Information Systems MRP material requirement planning NAVAIR Naval Air Systems Command viii DoD Depot-Level Reparable Supply...planning ( MRP ), which is run on the 15th of the month. The output of MRP is a time-phased buy and repair induction plan based on pro- jected demands...nine months in advance of the FY, planners begin work on the command schedule for the following year. From March through August, the monthly MRP

  5. DEPOT system for the creation of a translator from the COC language

    International Nuclear Information System (INIS)

    Kehnig, Kh.; Lehttsch, Yu.; Nefed'eva, L.S.; Shtiller, G.

    1976-01-01

    Approaches to the creation of specialized languages and their translators are given. The DENOT system for developing translators from various specialized languages is described. Use of the system was made to translate the STS (spectra treatment system) language into the FORTRAN language.The language of STS was realized with help of DEPOT on the BESM-6 computer. The DEROT system installed at various computer provides for simple and rapid transition from one computer to the other

  6. Tooele Army Depot Revised Final Site-Wide Ecological Risk Assessment. Volume I.

    Science.gov (United States)

    1998-02-01

    which is immediately east of the depot. Properties to the north of TEAD are used primarily for pasture and cultivation , and to the west and south, for...for the TEAD facility, the types of contaminants present, and the ecotoxicological effects that could be expected due to contaminant exposure. This...questions: • Were the analytical detection limits low enough to be ecotoxicologically relevant (i.e., to be protective of ecological receptors with

  7. Obesity associated disease risk: the role of inherent differences and location of adipose depots.

    Science.gov (United States)

    Hill, Jessica H; Solt, Claudia; Foster, Michelle T

    2018-03-16

    Obesity and associated metabolic co-morbidities are a worldwide public health problem. Negative health outcomes associated with obesity, however, do not arise from excessive adiposity alone. Rather, deleterious outcomes of adipose tissue accumulation are a result of how adipocytes are distributed to individual regions in the body. Due to our increased understanding of the dynamic relationship that exists between specific adipose depots and disease risk, an accurate characterization of total body adiposity as well as location is required to properly evaluate a population's disease risk. Specifically, distinctive tissue depots within the body include the lower body, upper body and abdominal (deep and superficial) subcutaneous regions, as well as visceral (mesenteric and omental) regions. Upper body and visceral adipose tissues are highly associated with metabolic dysfunction and chronic disease development, whereas lower body gluteofemoral subcutaneous adipose tissue imparts protection against diet-induced metabolic derangement. Each adipose depot functions distinctly as an endocrine organ hence it has a different level of impact on health outcomes. Effluent from adipose tissue can modulate the functions of other tissues, whilst receiving differential communication from the rest of the body via central nervous system innervation, metabolites and other signaling molecules. More so, adipose depots contain a diverse reservoir of tissue-resident immune cells that play an integral part in both maintaining tissue homeostasis, as well as propagating metabolically-induced inflammation. Overall, the conceptualization of obesity and associated risks needs updating to reflect the complexities of obesity. We review adipose tissue characteristics that are linked to deleterious or beneficial adipose tissue distributions.

  8. Implementation of Improved Management Control of Aviation Depot Level Repairable Funds

    Science.gov (United States)

    1986-12-01

    for comparing and testing. Pf ter Drucker states that ". . . control is an ambiguous word. It means the abiliti to direct oneself and one’s work. It...Frequency 50 LIST OF REFERENCES 1. Drucker , Peter F., The Practice of Management , Harper and Brothers Publishers, 1954. 2. Terry, George R., Principles of...NAVAL POSTGRADUATE SCHOOLMonterey, California 0- 6~~VI E1B9 87THESIS I IMPLEMENTATION OF IMPROVED MANAGEMENT CONTROL OF AVIATION DEPOT LEVEL

  9. Sustained Release of Antibiotics from Injectable and Thermally Responsive Polypeptide Depots

    OpenAIRE

    Adams, Samuel B.; Shamji, Mohammed F.; Nettles, Dana L.; Hwang, Priscilla; Setton, Lori A.

    2009-01-01

    Biodegradable polymeric scaffolds are of interest for delivering antibiotics to local sites of infection in orthopaedic applications, such as bone and diarthrodial joints. The objective of this study was to develop a biodegradable scaffold with ease of drug loading in aqueous solution, while providing for drug depot delivery via syringe injection. Elastin-like polypeptides (ELPs) were used for this application, biopolymers of repeating pentapeptide sequences that were thermally triggered to u...

  10. Control of Adipocyte Differentiation in Different Fat Depots; Implications for Pathophysiology or Therapy

    Directory of Open Access Journals (Sweden)

    Xiuquan eMa

    2015-01-01

    Full Text Available Adipocyte differentiation and its impact on restriction or expansion of particular adipose tissue depots has physiological and pathophysiological significance in view of the different functions of these depots. Brown or beige fat [BAT] expansion can enhance thermogenesis, lipid oxidation, insulin sensitivity and glucose tolerance; conversely expanded visceral fat [VAT] is associated with insulin resistance, low grade inflammation, dyslipidaemia and cardiometabolic risk. The largest depot, subcutaneous white fat [WAT], has important beneficial characteristics including storage of lipid out of harms way and secretion of adipokines, especially leptin and adiponectin, with positive metabolic effects including lipid oxidation, energy utilisation, enhanced insulin action and an anti-inflammatory role. The absence of these functions in lipodystrophies leads to major metabolic disturbances. An ability to expand WAT adipocyte differentiation would seem an important defence mechanism against the detrimental effects of energy excess and limit harmful accumulation of lipid in ectopic sites, such as liver and muscle.Adipocyte differentiation involves a transcriptional cascade with PPARg being most important in WAT but less so in VAT, with increased angiogenesis also critical. The transcription factor, Islet1, is fairly specific to VAT and in vitro inhibits adipocyte differentiation. The physiological importance of Islet1 requires further study. Basic control of differentiation is similar in BAT but important differences include the effect of PGC-1a on mitochondrial biosynthesis and upregulation of UCP1; also PRDM16 plays a pivotal role in expression of the BAT phenotype.Modulation of the capacity or function of these different adipose tissue depots, by altering adipocyte differentiation or other means, holds promise for interventions that can be helpful in human disease, particularly cardiometabolic disorders associated with the world wide explosion of

  11. Evidence for Environmental Contamination in Residential Neighborhoods Surrounding the Defense Depot of Memphis, Tennessee

    Directory of Open Access Journals (Sweden)

    Cynthia Warrick

    2006-09-01

    Full Text Available An interdisciplinary environmental assessment team from the Howard University Environmental Justice Partnership (HUEJP conducted a site visit and assessment of the Defense Depot of Memphis, Tennessee in February of 2000. This depot was built in the late 1940’s for storage of numerous chemicals and munitions. As the years progressed, many Memphis citizens have grown to believe that the activities and chemical stockpile located at this site have negatively affected the health environment of their residents. There is anecdotal evidence and documentation of numerous cancers and other illnesses in those local territories, and specifically, at the Memphis Depot site. Currently, this depot is closed and in remediation by the local government. Particularly, citizens of the Rozelle community have started a campaign to investigate any signs of exposure pathways to noted health risks. The HUEJP was contacted and asked to investigate the community concerns. Obliging to the request, we aimed to sample at three drainage sites and a residential site, talk to local citizens, and gain any additional information that would be helpful in relieving anxiety in the Rozelle community. Soil, sediment, and water samples were collected and analyzed for total organic carbon, inorganic anions, and heavy metals. These data show that for the four sites sampled, the highest concentrations of organic compounds and heavy metals were located either within a residential area or in an area with a direct transport pathway to the community. Atomic absorption analysis revealed detectable amounts of cadmium, lead and chromium metals at all sites with direct transport pathways into the residential community, with chromium concentrations being far in excess of the EPA standard limits.

  12. Employing organizational modeling and simulation of the KC-135 depot's flight controls repair cell

    OpenAIRE

    Paskin, Matthew A.; Trevino, Alice W.; Ferrer, Geraldo; Dillard, John T.

    2008-01-01

    Today’s environment of increased operations tempo is stressing the KC- 135 Stratotanker fleet. With an 80-year life span expectancy, effectively maintaining these aircraft is challenging. This research modeled the KC- 135 programmed depot maintenance (PDM) flight controls repair cell to identify improvement opportunities within the repair process. Computational organizational modeling (COM) incorporates the human element along with organizational design theory. By employing ...

  13. HALF-DOSE DEPOT TRIPTORELIN COMPARABLE TO REDUCED DAILY BUSERELIN: A RANDOMIZED CLINICAL TRIAL

    Directory of Open Access Journals (Sweden)

    L. Safdarian

    2007-09-01

    Full Text Available Pituitary suppression by depot GnRH agonist may be excessive for ovarian stimulation. This study compares the efficacy of a single half-dose depot triptorelin and reduced-dose daily buserelin in a long protocol ICSI/ET. METHODS: A total of 182 patients were randomized into two groups using sealed envelopes. Pituitary desensitization was obtained in group 1 (91 patients with half-dose (1.87 mg depot triptorelin in the mid-luteal phase of their menstrual cycle, and in group 2 (91 patients with standard daily dose (0.5 mg buserelin, which was then reduced to 0.25 mg at the start of human menopausal gonadotropin (HMG stimulation. RESULTS: No significant differences were found among those who received HCG in terms of clinical pregnancy rate (34.4% in both groups, implantation rate (14.8% in group 1 versus 11.1% in group 2, fertilization rate (93.3 versus 95.6%, poor response rate (11.1 versus 6.7%, and miscarriage rate (11.1 versus 7.8%. No significant differences were seen in number of HMG ampoules used, follicles at HCG administration, and oocytes retrieved. The number of days of stimulation was significantly reduced in group 2 (11.2 +/- 1.8 in group 1 versus 10.6 +/- 1.9, p = 0.030. CONCLUSION: A half-dose of depot triptorelin can be successfully used in ovarian stimulation instead of reduced-dose daily buserelin, with more patient comfort and reduced stress and cost of injections.

  14. The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women

    Directory of Open Access Journals (Sweden)

    N V Mazurina

    2013-03-01

    Full Text Available Реферат по материалам статьи The relationship between fat depot-specific preadipocyte differentiation and metabolic syndrome in obese women. Park HТ, Lee ES, Cheon EP, Lee DR, Yang K-S, Kim YT, Hur JY, Kim SH, Lee KW, Kim T. Clinical Endocrinology 2012; 76, 59-66.

  15. AUTOMATED DETECTION OF OIL DEPOTS FROM HIGH RESOLUTION IMAGES: A NEW PERSPECTIVE

    Directory of Open Access Journals (Sweden)

    A. O. Ok

    2015-03-01

    Full Text Available This paper presents an original approach to identify oil depots from single high resolution aerial/satellite images in an automated manner. The new approach considers the symmetric nature of circular oil depots, and it computes the radial symmetry in a unique way. An automated thresholding method to focus on circular regions and a new measure to verify circles are proposed. Experiments are performed on six GeoEye-1 test images. Besides, we perform tests on 16 Google Earth images of an industrial test site acquired in a time series manner (between the years 1995 and 2012. The results reveal that our approach is capable of detecting circle objects in very different/difficult images. We computed an overall performance of 95.8% for the GeoEye-1 dataset. The time series investigation reveals that our approach is robust enough to locate oil depots in industrial environments under varying illumination and environmental conditions. The overall performance is computed as 89.4% for the Google Earth dataset, and this result secures the success of our approach compared to a state-of-the-art approach.

  16. Employment-based reinforcement of adherence to depot naltrexone in unemployed opioid-dependent adults: a randomized controlled trial.

    Science.gov (United States)

    Everly, Jeffrey J; DeFulio, Anthony; Koffarnus, Mikhail N; Leoutsakos, Jeannie-Marie S; Donlin, Wendy D; Aklin, Will M; Umbricht, Annie; Fingerhood, Michael; Bigelow, George E; Silverman, Kenneth

    2011-07-01

    Naltrexone can be used to treat opioid dependence, but patients refuse to take it. Extended-release depot formulations may improve adherence, but long-term adherence rates to depot naltrexone are not known. This study determined long-term rates of adherence to depot naltrexone and whether employment-based reinforcement can improve adherence. Participants who were inducted onto oral naltrexone were assigned randomly to contingency (n = 18) or prescription (n = 17) groups. Participants were offered six depot naltrexone injections and invited to work at the therapeutic workplace on week days for 26 weeks, where they earned stipends for participating in job skills training. Contingency participants were required to accept naltrexone injections to maintain workplace access and to maintain maximum pay. Prescription participants could work independently of whether they accepted injections. The therapeutic workplace, a model employment-based intervention for drug addiction and unemployment. Opioid-dependent unemployed adults. Depot naltrexone injections accepted and opiate-negative urine samples. Contingency participants accepted significantly more naltrexone injections than prescription participants (81% versus 42%), and were more likely to accept all injections (66% versus 35%). At monthly assessments (with missing urine samples imputed as positive), the groups provided similar percentages of samples negative for opiates (74% versus 62%) and for cocaine (56% versus 54%). Opiate-positive samples were more likely when samples were also positive for cocaine. Employment-based reinforcement can maintain adherence to depot naltrexone. Future research should determine whether persistent cocaine use compromises naltrexone's effect on opiate use. Workplaces may be useful for promoting sustained adherence to depot naltrexone. © 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

  17. Six-month gonadotropin releasing hormone (GnRH agonist depots provide efficacy, safety, convenience, and comfort

    Directory of Open Access Journals (Sweden)

    Phillips JM

    2011-07-01

    Full Text Available E David Crawford, Jason M PhillipsUniversity of Colorado Health Sciences Center, Aurora, CO, USAAbstract: Two different 6-month GnRH agonist depot formulations approved for palliative treatment of advanced and metastatic prostate cancer in the United States – leuprolide acetate 45 mg and triptorelinpalmoate 22.5 mg – provide patients with efficacy and safety comparable to those of existing 1-, 3-, and 4-month GnRH agonist depots. However, the 6-month formulations can increase patient convenience, comfort, and compliance by reducing the number of physician visits and injections required. At the conclusion of their pivotal trials, the 6-month formulations demonstrated efficacy rates in achieving chemical castration (serum testosterone #50 ng/dL that ranged between 93% and 99%. As with existing GnRH agonist depot formulations, hot flashes represented the most common adverse event reported in trials of 6-month leuprolide acetate or triptorelin. As such, these products may prove useful not only for their labeled indication, but also as adjuncts to other treatments such as radical prostatectomy, radiotherapy, and chemotherapy. We recommend further research, including head-to-head trials between the 6-month GnRH depots, to refine our understanding of these products.Keywords: prostate cancer, leuprorelin, leuprolide, triptorelin, 6-month depot, testosterone

  18. Eradicating hepatitis C virus ameliorates insulin resistance without change in adipose depots.

    Science.gov (United States)

    Milner, K-L; Jenkins, A B; Trenell, M; Tid-Ang, J; Samocha-Bonet, D; Weltman, M; Xu, A; George, J; Chisholm, D J

    2014-05-01

    Chronic hepatitis C (CHC) is associated with lipid-related changes and insulin resistance; the latter predicts response to antiviral therapy, liver disease progression and the risk of diabetes. We sought to determine whether insulin sensitivity improves following CHC viral eradication after antiviral therapy and whether this is accompanied by changes in fat depots or adipokine levels. We compared 8 normoglycaemic men with CHC (genotype 1 or 3) before and at least 6 months post viral eradication and 15 hepatitis C antibody negative controls using an intravenous glucose tolerance test and two-step hyperinsulinaemic-euglycaemic clamp with [6,6-(2) H2 ] glucose to assess peripheral and hepatic insulin sensitivity. Magnetic resonance imaging and spectroscopy quantified abdominal fat compartments, liver and intramyocellular lipid. Peripheral insulin sensitivity improved (glucose infusion rate during high-dose insulin increased from 10.1 ± 1.6 to 12 ± 2.1 mg/kg/min/, P = 0.025), with no change in hepatic insulin response following successful viral eradication, without any accompanying change in muscle, liver or abdominal fat depots. There was corresponding improvement in incremental glycaemic response to intravenous glucose (pretreatment: 62.1 ± 8.3 vs post-treatment: 56.1 ± 8.5 mm, P = 0.008). Insulin sensitivity after viral clearance was comparable to matched controls without CHC. Post therapy, liver enzyme levels decreased but, interestingly, levels of glucagon, fatty acid-binding protein and lipocalin-2 remained elevated. Eradication of the hepatitis C virus improves insulin sensitivity without alteration in fat depots, adipokine or glucagon levels, consistent with a direct link of the virus with insulin resistance. © 2013 John Wiley & Sons Ltd.

  19. The nuclear retinoid-related orphan receptor RORα controls circadian thermogenic programming in white fat depots.

    Science.gov (United States)

    Monnier, Chloé; Auclair, Martine; Le Cam, Gala; Garcia, Marie-Pauline; Antoine, Bénédicte

    2018-04-01

    The RORα-deficient staggerer (sg/sg) mouse is lean and resistant to diet-induced obesity. Its thermogenic activity was shown to be increased not only in brown adipose tissue (BAT), but also in subcutaneous white adipose tissue (WAT) where UCP1 content was enhanced, however, without Prdm16 coexpression. Our observation of partial multilocular lipid morphology of WAT in sg/sg mice both in the inguinal and perigonadal sites led us to focus on the phenotype of both fat depots. Because RORα is a nuclear factor acting in the clock machinery, we looked at the circadian expression profile of genes involved in thermogenesis and browning in WAT and BAT depots of sg/sg and WT mice, through real-time quantitative PCR and western blotting. This 24-h period approach revealed both a rhythmic expression of thermogenic genes in WAT and an increased browning of all the WAT depots tested in sg/sg mice that indeed involved the canonical browning process (through induction of Pgc-1α and Prdm16). This was associated with an enhanced isoproterenol-induced oxygen consumption rate of WAT explants from sg/sg mice, which was reproducible in WT explants by treatment with a RORα inverse agonist SR 3335, that induced a parallel increase in the UCP1 protein. Inhibitors of browning differentiation, such as TLE3 and RIP140, could be new targets of RORα that would be rather implicated in the whitening of adipocytes. Our study showed the pivotal role of RORα as an inhibitor of the thermogenic program in WAT, the role that could be counteracted in vivo with the RORα antagonists currently in development. © 2018 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  20. Abdominal fat sub-depots and energy expenditure: Magnetic resonance imaging study.

    Science.gov (United States)

    Serfaty, Dana; Rein, Michal; Schwarzfuchs, Dan; Shelef, Ilan; Gepner, Yftach; Bril, Nitzan; Cohen, Noa; Shemesh, Elad; Sarusi, Benjamin; Kovsan, Julia; Kenigsbuch, Shira; Chassidim, Yoash; Golan, Rachel; Witkow, Shula; Henkin, Yaakov; Stampfer, Meir J; Rudich, Assaf; Shai, Iris

    2017-06-01

    We aimed to assess the association between the distinct abdominal sub-depots and resting energy expenditure (REE). We performed magnetic resonance imaging (MRI) to quantify abdominal visceral-adipose-tissue (VAT), deep-subcutaneous-adipose-tissue (deep-SAT), and superficial-subcutaneous-adipose-tissue (superficial-SAT). We measured REE by indirect-calorimetry. Non-exercise activity thermogenesis (NEAT) [1-3 metabolic equivalents (METs)] and exercise thermogenesis (activities of 4+MET S ) were estimated based on 6-days of accelerometry to assess total physical activity energy expenditure (PAEE). We studied 282 participants: 249 men [mean age = 47.4 years, body-mass-index (BMI) = 31 kg/m 2 , mean VAT proportion from total abdominal fat = 34.5%, mean superficial-SAT proportion from total abdominal fat = 24.3%] and 33 women (mean age = 51.2 years, BMI = 30.1 kg/m 2 , mean VAT proportion from total abdominal fat = 22.8%, mean superficial-SAT proportion from total abdominal fat = 37.8%). As expected, women had lower REE [by 32.4% (1488 ± 234 kcal/day vs. 1971 ± 257 kcal/day; p abdominal VAT was the dominant proportional depot, had higher REE (1964 ± 297 kcal/day vs. 1654 ± 352 kcal/day; p Abdominal fat distribution patterns are associated with varying levels of resting energy expenditure, potentially reflecting different metabolic rates of adipose sub-depots and providing an anatomic/anthropometric link to physiological obese sub-phenotypes. Copyright © 2016 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

  1. Direct Evidence of Brown Adipocytes in Different Fat Depots in Children

    Science.gov (United States)

    Rockstroh, Denise; Landgraf, Kathrin; Wagner, Isabel Viola; Gesing, Julia; Tauscher, Roy; Lakowa, Nicole; Kiess, Wieland; Bühligen, Ulf; Wojan, Magdalena; Till, Holger; Blüher, Matthias; Körner, Antje

    2015-01-01

    Recent studies suggested the persistence of brown adipocytes in adult humans, as opposed to being exclusively present in infancy. In this study, we investigated the presence of brown-like adipocytes in adipose tissue (AT) samples of children and adolescents aged 0 to 18 years and evaluated the association with age, location, and obesity. For this, we analysed AT samples from 131 children and 23 adults by histological, immunohistochemical and expression analyses. We detected brown-like and UCP1 positive adipocytes in 10.3% of 87 lean children (aged 0.3 to 10.7 years) and in one overweight infant, whereas we did not find brown adipocytes in obese children or adults. In our samples, the brown-like adipocytes were interspersed within white AT of perirenal, visceral and also subcutaneous depots. Samples with brown-like adipocytes showed an increased expression of UCP1 (>200fold), PRDM16 (2.8fold), PGC1α and CIDEA while other brown/beige selective markers, such as PAT2, P2RX5, ZIC1, LHX8, TMEM26, HOXC9 and TBX1 were not significantly different between UCP1 positive and negative samples. We identified a positive correlation between UCP1 and PRDM16 within UCP1 positive samples, but not with any other brown/beige marker. In addition, we observed significantly increased PRDM16 and PAT2 expression in subcutaneous and visceral AT samples with high UCP1 expression in adults. Our data indicate that brown-like adipocytes are present well beyond infancy in subcutaneous depots of non-obese children. The presence was not restricted to typical perirenal locations, but they were also interspersed within WAT of visceral and subcutaneous depots. PMID:25706927

  2. Army Depot Maintenance: More Effective Use of Organic and Contractor Resources

    Science.gov (United States)

    1990-06-04

    terkerrny (PA) RRAD Red River (TX) IBAD Lexingtor).Bluegrass (KY) 3MPUAD Pueblo (CO) 2000 ANAD CCAD TEAD TOAD SAAO LEAD FMD LBAD PUAfl j] Aut)’onzed Onboard...until it is received by the contractor. That problem could be eliminated by redesigning the process. Specifically, the FTA document that notifies the...should revise CCSS to allow the FTM document to generate an image to LCA, the FTA to create a due-in to the contractor, and CCSS to determine the depot

  3. Combined use of Dexa-Scheroson and Primobolan-Depot in radiation therapy

    Energy Technology Data Exchange (ETDEWEB)

    Nagai, J [Shizuoka Rosai Hospital (Japan)

    1976-05-01

    Dexa-Scheroson and Primobolan-Depot were used together with radiation therapy (Linac therapy) required in 13 cases. The following results were obtained. The decrease in white cell counts, which often occurs in radiation therapy, was inhibited by the drugs. There was no case in which radiation therapy should necessarily withdraw because the number of leuckocytes was decreased to less than 3,000. The patients whose liver function was poor should be treated with both drugs at the beginning of radiation therapy. It was found that the combined use of the drugs is effective in the prevention and the treatment of cerebral edema in radiation therapy of intracranial lesion.

  4. KANDUNGAN Pb, Cd, Hg DALAM AIR MINUM DARI DEPOT AIR MINUM ISI ULANG DI JAKARTA, TANGERANG, DAN BEKASI

    Directory of Open Access Journals (Sweden)

    Athena Athena

    2012-11-01

    Full Text Available A study on chemical quality of drinking water from reffil depots was done in Jakarta, Tangerang, and Bekasi in 2003 to determine the contents of heavy metals such as lead (Pb, cadmium, (Cd, and Mercury (Hg. A total of 38 refill depots was selected as samples. Data were collected by water sampling collection and water analysis, and interview with operators and association personal using questionairs. Water samples were analyzed using Atomic Absorption Spectrophotometer (AAS to examine the contents of their heavy metals based on raw water and drinking water standards. The results showed that the treatment processed were filtration and disinfection. However, the contents of heavy metals in the two types of water samples still complied with the standards stated in Health Ministerial Decree no 906 in the year 2002.   Keywords: heavy metals, drinking water, drinking water refill depots

  5. Elucidation of molecular mechanisms of physiological variations between bovine subcutaneous and visceral fat depots under different nutritional regimes.

    Directory of Open Access Journals (Sweden)

    Josue Moura Romao

    Full Text Available Adipose tissue plays a critical role in energy homeostasis and metabolism. There is sparse understanding of the molecular regulation at the protein level of bovine adipose tissues, especially within different fat depots under different nutritional regimes. The objective of this study was to analyze the differences in protein expression between bovine subcutaneous and visceral fat depots in steers fed different diets and to identify the potential regulatory molecular mechanisms of protein expression. Subcutaneous and visceral fat tissues were collected from 16 British-continental steers (15.5 month old fed a high-fat diet (7.1% fat, n=8 or a control diet (2.7% fat, n=8. Protein expression was profiled using label free quantification LC-MS/MS and expression of selected transcripts was evaluated using qRT-PCR. A total of 682 proteins were characterized and quantified with fat depot having more impact on protein expression, altering the level of 51.0% of the detected proteins, whereas diet affected only 5.3%. Functional analysis revealed that energy production and lipid metabolism were among the main functions associated with differentially expressed proteins between fat depots, with visceral fat being more metabolically active than subcutaneous fat as proteins associated with lipid and energy metabolism were upregulated. The expression of several proteins was significantly correlated to subcutaneous fat thickness and adipocyte size, indicating their potential as adiposity markers. A poor correlation (r=0.245 was observed between mRNA and protein levels for 9 genes, indicating that many proteins may be subjected to post-transcriptional regulation. A total of 8 miRNAs were predicted to regulate more than 20% of lipid metabolism proteins differentially expressed between fat depots, suggesting that miRNAs play a role in adipose tissue regulation. Our results show that proteomic changes support the distinct metabolic and physiological characteristics

  6. Elucidation of molecular mechanisms of physiological variations between bovine subcutaneous and visceral fat depots under different nutritional regimes.

    Science.gov (United States)

    Romao, Josue Moura; Jin, Weiwu; He, Maolong; McAllister, Tim; Guan, Le Luo

    2013-01-01

    Adipose tissue plays a critical role in energy homeostasis and metabolism. There is sparse understanding of the molecular regulation at the protein level of bovine adipose tissues, especially within different fat depots under different nutritional regimes. The objective of this study was to analyze the differences in protein expression between bovine subcutaneous and visceral fat depots in steers fed different diets and to identify the potential regulatory molecular mechanisms of protein expression. Subcutaneous and visceral fat tissues were collected from 16 British-continental steers (15.5 month old) fed a high-fat diet (7.1% fat, n=8) or a control diet (2.7% fat, n=8). Protein expression was profiled using label free quantification LC-MS/MS and expression of selected transcripts was evaluated using qRT-PCR. A total of 682 proteins were characterized and quantified with fat depot having more impact on protein expression, altering the level of 51.0% of the detected proteins, whereas diet affected only 5.3%. Functional analysis revealed that energy production and lipid metabolism were among the main functions associated with differentially expressed proteins between fat depots, with visceral fat being more metabolically active than subcutaneous fat as proteins associated with lipid and energy metabolism were upregulated. The expression of several proteins was significantly correlated to subcutaneous fat thickness and adipocyte size, indicating their potential as adiposity markers. A poor correlation (r=0.245) was observed between mRNA and protein levels for 9 genes, indicating that many proteins may be subjected to post-transcriptional regulation. A total of 8 miRNAs were predicted to regulate more than 20% of lipid metabolism proteins differentially expressed between fat depots, suggesting that miRNAs play a role in adipose tissue regulation. Our results show that proteomic changes support the distinct metabolic and physiological characteristics observed between

  7. A constructive heuristic for time-dependent multi-depot vehicle routing problem with time-windows and heterogeneous fleet

    Directory of Open Access Journals (Sweden)

    Behrouz Afshar-Nadjafi

    2017-01-01

    Full Text Available In this paper, we consider the time-dependent multi-depot vehicle routing problem. The objective is to minimize the total heterogeneous fleet cost assuming that the travel time between locations depends on the departure time. Also, hard time window constraints for the customers and limitation on maximum number of the vehicles in depots must be satisfied. The problem is formulated as a mixed integer programming model. A constructive heuristic procedure is proposed for the problem. Also, the efficiency of the proposed algorithm is evaluated on 180 test problems. The obtained computational results indicate that the procedure is capable to obtain a satisfying solution.

  8. Design of Hybrid Gels Based on Gellan-Cholesterol Derivative and P90G Liposomes for Drug Depot Applications

    Directory of Open Access Journals (Sweden)

    Nicole Zoratto

    2017-05-01

    Full Text Available Gels are extensively studied in the drug delivery field because of their potential benefits in therapeutics. Depot gel systems fall in this area, and the interest in their development has been focused on long-lasting, biocompatible, and resorbable delivery devices. The present work describes a new class of hybrid gels that stem from the interaction between liposomes based on P90G phospholipid and the cholesterol derivative of the polysaccharide gellan. The mechanical properties of these gels and the delivery profiles of the anti-inflammatory model drug diclofenac embedded in such systems confirmed the suitability of these hybrid gels as a good candidate for drug depot applications.

  9. Insulin, IGF-1, and GH Receptors Are Altered in an Adipose Tissue Depot-Specific Manner in Male Mice With Modified GH Action.

    Science.gov (United States)

    Hjortebjerg, Rikke; Berryman, Darlene E; Comisford, Ross; Frank, Stuart J; List, Edward O; Bjerre, Mette; Frystyk, Jan; Kopchick, John J

    2017-05-01

    Growth hormone (GH) is a determinant of glucose homeostasis and adipose tissue (AT) function. Using 7-month-old transgenic mice expressing the bovine growth hormone (bGH) gene and growth hormone receptor knockout (GHR-/-) mice, we examined whether changes in GH action affect glucose, insulin, and pyruvate tolerance and AT expression of proteins involved in the interrelated signaling pathways of GH, insulinlike growth factor 1 (IGF-1), and insulin. Furthermore, we searched for AT depot-specific differences in control mice. Glycated hemoglobin levels were reduced in bGH and GHR-/- mice, and bGH mice displayed impaired gluconeogenesis as judged by pyruvate tolerance testing. Serum IGF-1 was elevated by 90% in bGH mice, whereas IGF-1 and insulin were reduced by 97% and 61% in GHR-/- mice, respectively. Igf1 RNA was increased in subcutaneous, epididymal, retroperitoneal, and brown adipose tissue (BAT) depots in bGH mice (mean increase ± standard error of the mean in all five depots, 153% ± 27%) and decreased in all depots in GHR-/- mice (mean decrease, 62% ± 4%). IGF-1 receptor expression was decreased in all AT depots of bGH mice (mean decrease, 49% ± 6%) and increased in all AT depots of GHR-/- mice (mean increase, 94% ± 8%). Insulin receptor expression was reduced in retroperitoneal, mesenteric, and BAT depots in bGH mice (mean decrease in all depots, 56% ± 4%) and augmented in subcutaneous, retroperitoneal, mesenteric, and BAT depots in GHR-/- mice (mean increase: 51% ± 1%). Collectively, our findings indicate a role for GH in influencing hormone signaling in AT in a depot-dependent manner. Copyright © 2017 Endocrine Society.

  10. A tabu-search heuristic for solving the multi-depot vehicle scheduling problem

    Directory of Open Access Journals (Sweden)

    Gilmar D'Agostini Oliveira Casalinho

    2014-08-01

    Full Text Available Currently the logistical problems are relying quite significantly on Operational Research in order to achieve greater efficiency in their operations. Among the problems related to the vehicles scheduling in a logistics system, the Multiple Depot Vehicle Scheduling Problem (MDVSP has been addressed in several studies. The MDVSP presupposes the existence of depots that affect the planning of sequences to which travel must be performed. Often, exact methods cannot solve large instances encountered in practice and in order to take them into account, several heuristic approaches are being developed. The aim of this study was thus to solve the MDVSP using a meta-heuristic based on tabu-search method. The main motivation for this work came from the indication that only recently the use of meta-heuristics is being applied to MDVSP context (Pepin et al. 2008 and, also, the limitations listed by Rohde (2008 in his study, which used the branch-and-bound in one of the steps of the heuristic presented to solve the problem, which has increased the time resolution. The research method for solving this problem was based on adaptations of traditional techniques of Operational Research, and provided resolutions presenting very competitive results for the MDVSP such as the cost of the objective function, number of vehicles used and computational time.

  11. Performance of clustering techniques for solving multi depot vehicle routing problem

    Directory of Open Access Journals (Sweden)

    Eliana M. Toro-Ocampo

    2016-01-01

    Full Text Available The vehicle routing problem considering multiple depots is classified as NP-hard. MDVRP determines simultaneously the routes of a set of vehicles and aims to meet a set of clients with a known demand. The objective function of the problem is to minimize the total distance traveled by the routes given that all customers must be served considering capacity constraints in depots and vehicles. This paper presents a hybrid methodology that combines agglomerative clustering techniques to generate initial solutions with an iterated local search algorithm (ILS to solve the problem. Although previous studies clustering methods have been proposed like strategies to generate initial solutions, in this work the search is intensified on the information generated after applying the clustering technique. Besides an extensive analysis on the performance of techniques, and their effect in the final solution is performed. The operation of the proposed methodology is feasible and effective to solve the problem regarding the quality of the answers and computational times obtained on request evaluated literature

  12. Relationships between rodent white adipose fat pads and human white adipose fat depots

    Directory of Open Access Journals (Sweden)

    Daniella E. Chusyd

    2016-04-01

    Full Text Available The objective of this review was to compare and contrast the physiological and metabolic profiles of rodent white adipose fat pads with white adipose fat depots in humans. Human fat distribution and its metabolic consequences have received extensive attention, but much of what has been tested in translational research has relied heavily on rodents. Unfortunately, the validity of using rodent fat pads as a model of human adiposity has received less attention. There is a surprisingly lack of studies demonstrating an analogous relationship between rodent and human adiposity on obesity-related comorbidities. Therefore, we aimed to compare known similarities and disparities in terms of white adipose tissue development and distribution, sexual dimorphism, weight loss, adipokine secretion, and aging. While the literature supports the notion that many similarities exist between rodents and humans, notable differences emerge related to fat deposition and function of white adipose tissue. Thus, further research is warranted to more carefully define the strengths and limitations of rodent white adipose tissue as a model for humans, with a particular emphasis on comparable fat depots, such as mesenteric fat.

  13. Feasibility study on reduction of gasoline emissions from oil depots and gasoline stations in Indonesia

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    A field survey was conducted of oil shipment depots in Java and Bali islands owned by Indonesia's state-run oil company to study measures for reduction in greenhouse effect gas emissions. Studies were made on the grasp of the amount of the hydrocarbon vapor emitted into the air, the amount of the gasoline recovered in case of adopting the vapor emission preventive technology, equipment cost/operational cost, etc. Concretely, the following three were studied: change of the gasoline storage tank to the inner floating roof type, and prevention of evaporation loss at the time of receiving and breathing loss caused by temperature changes; replacement with the vapor recovery type loading arm to recover gasoline vapor generated at the time of shipment/filling, and installation of the vapor recovery unit to recover vapor as gasoline; vapor balance system to recover in underground tank the gasoline vapor generated at the time of filling gasoline at gas station. As a result of the study, the recovered gasoline amount was 66,393 Kl/y and the CO2 reduction amount was 14,474 t/y at oil shipment depots and approximately 650 gasoline stations in Jakarta and Surabaya. (NEDO)

  14. [A preliminary study of low dosage zuclopenthixol depot in Alzheimer's disease].

    Science.gov (United States)

    Robles, A; Rodríguez Navarrete, F J; Taboada, O; Docasar, L; Páramo, M; Noya, M

    1996-03-01

    Persistent psychomotor agitation and psychotic ideation in patients with Alzheimer's disease are normally treated orally with antipsychotic drugs and are occasionally treated with other drugs. Neuroleptics administered intramuscularly at very low doses are an alternative, especially when the patient rejects medicine as a results of his or her anosognosia or of paranoid manifestations. We present the results we obtained after observing the effects of depot zuclopenthixol in six patients with probable Alzheimer's disease (based upon NINCDS-ADRDA criteria). Psychic abnormalities were assessed as per the Brief Psychiatric Rating Scale (BPRS), the Scale for the Assessment of Positive Symptoms (SAPS) and the Scale for the Assessment of Negative Symptoms (SANS). Possible extrapyramidal side effects were evaluated by means of the Abnormal Involuntary Movement Scale (AIMS). Initially 60 mg (0.3 ml) were administered intramuscularly and successive doses could be modified by +/-20 mg (0.1 ml) according to results seen on the various scales. During the first six weeks of treatment progressive improvement was noted on all three psychic functions scales in all patients. Between the sixth and twelfth weeks improvement continued although without significant change. The AIMS did not show significant changes in the twelve weeks of follow-up. We consider depot zuclopenthixol at low doses as efficacious in treating persistent psychomotor agitation and/or psychotic manifestations of Alzheimer's disease. No undesired side effects were observed in our group after a twelve week follow-up.

  15. A two-stage approach to the depot shunting driver assignment problem with workload balance considerations.

    Science.gov (United States)

    Wang, Jiaxi; Gronalt, Manfred; Sun, Yan

    2017-01-01

    Due to its environmentally sustainable and energy-saving characteristics, railway transportation nowadays plays a fundamental role in delivering passengers and goods. Emerged in the area of transportation planning, the crew (workforce) sizing problem and the crew scheduling problem have been attached great importance by the railway industry and the scientific community. In this paper, we aim to solve the two problems by proposing a novel two-stage optimization approach in the context of the electric multiple units (EMU) depot shunting driver assignment problem. Given a predefined depot shunting schedule, the first stage of the approach focuses on determining an optimal size of shunting drivers. While the second stage is formulated as a bi-objective optimization model, in which we comprehensively consider the objectives of minimizing the total walking distance and maximizing the workload balance. Then we combine the normalized normal constraint method with a modified Pareto filter algorithm to obtain Pareto solutions for the bi-objective optimization problem. Furthermore, we conduct a series of numerical experiments to demonstrate the proposed approach. Based on the computational results, the regression analysis yield a driver size predictor and the sensitivity analysis give some interesting insights that are useful for decision makers.

  16. A two-stage approach to the depot shunting driver assignment problem with workload balance considerations.

    Directory of Open Access Journals (Sweden)

    Jiaxi Wang

    Full Text Available Due to its environmentally sustainable and energy-saving characteristics, railway transportation nowadays plays a fundamental role in delivering passengers and goods. Emerged in the area of transportation planning, the crew (workforce sizing problem and the crew scheduling problem have been attached great importance by the railway industry and the scientific community. In this paper, we aim to solve the two problems by proposing a novel two-stage optimization approach in the context of the electric multiple units (EMU depot shunting driver assignment problem. Given a predefined depot shunting schedule, the first stage of the approach focuses on determining an optimal size of shunting drivers. While the second stage is formulated as a bi-objective optimization model, in which we comprehensively consider the objectives of minimizing the total walking distance and maximizing the workload balance. Then we combine the normalized normal constraint method with a modified Pareto filter algorithm to obtain Pareto solutions for the bi-objective optimization problem. Furthermore, we conduct a series of numerical experiments to demonstrate the proposed approach. Based on the computational results, the regression analysis yield a driver size predictor and the sensitivity analysis give some interesting insights that are useful for decision makers.

  17. The disposal of low and intermediate-level radioactive wastes: the Elstow Storage Depot

    International Nuclear Information System (INIS)

    1983-10-01

    This document explains the role of NIREX (Nuclear Industry Radioactive Waste Executive) in planning for the safe disposal of low and intermediate-level radioactive wastes and outlines the plans for the investigation and possible development of a new shallow repository at the CEGB's Elstow Storage Depot, Bedfordshire. The site is conveniently located and is situated on a suitable geologic formation, the Oxford Clay. The next step is for NIREX to undertake site investigations and assess in detail the site's suitability. On the basis of this assessment NIREX will either confirm its interest in the site or reject it as unsuitable. If the site proves to be adequate for the development of a shallow repository then NIREX will seek the necessary planning approvals and authorisations for such a development. The development would involve the construction of new buildings and a programme of trench excavation, waste positioning and trench closure. Existing tenants at the Depot will be accommodated as far as possible. The existing road and rail networks would be used for delivering the packaged wastes. In designing and operating any repository the safety of the public and workforce, both now and in the future, will be of paramount importance. (author)

  18. The multi-depot electric vehicle location routing problem with time windows

    Directory of Open Access Journals (Sweden)

    Juan Camilo Paz

    2018-01-01

    Full Text Available In this paper, the Multi-Depot Electric Vehicle Location Routing Problem with Time Windows (MDVLRP is addressed. This problem is an extension of the MDVLRP, where electric vehicles are used instead of internal combustion engine vehicles. The recent development of this model is explained by the advantages of this technology, such as the diminution of carbon dioxide emissions, and the support that they can provide to the design of the logistic and energy-support structure of electric vehicle fleets. There are many models that extend the classical VRP model to take electric vehicles into consideration, but the multi-depot case for location-routing models has not been worked out yet. Moreover, we consider the availability of two energy supply technologies: the “Plug-in” Conventional Charge technology, and Battery Swapping Stations; options in which the recharging time is a function of the amount of energy to charge and a fixed time, respectively. Three models are proposed: one for each of the technologies mentioned above, and another in which both options are taken in consideration. The models were solved for small scale instances using C++ and Cplex 12.5. The results show that the models can be used to design logistic and energy-support structures, and compare the performance of the different options of energy supply, as well as measure the impact of these decisions on the overall distance traveled or other optimization objectives that could be worked on in the future.

  19. A Multi-Depot Two-Echelon Vehicle Routing Problem with Delivery Options Arising in the Last Mile Distribution

    NARCIS (Netherlands)

    Zhou, Lin; Baldacci, Roberto; Vigo, Daniele; Wang, Xu

    2018-01-01

    In this paper, we introduce a new city logistics problem arising in the last mile distribution of e-commerce. The problem involves two levels of routing problems. The first requires a design of the routes for a vehicle fleet located at the depots to transport the customer demands to a subset of the

  20. Double stimuli-responsive polymer systems: How to use crosstalk between pH- and thermosensitivity for drug depots

    Czech Academy of Sciences Publication Activity Database

    Bogomolova, Anna; Kaberov, Leonid; Sedláček, Ondřej; Filippov, Sergey K.; Štěpánek, Petr; Král, V.; Wang, X. Y.; Liu, S. L.; Ye, X. D.; Hrubý, Martin

    2016-01-01

    Roč. 84, November (2016), s. 54-64 ISSN 0014-3057 R&D Projects: GA MŠk(CZ) LH14292; GA ČR(CZ) GC15-10527J Institutional support: RVO:61389013 Keywords : drug depot formulation * double responsive system * pH-responsive polymer Subject RIV: CC - Organic Chemistry Impact factor: 3.531, year: 2016

  1. Deployment Strategy for Car-Sharing Depots by Clustering Urban Traffic Big Data Based on Affinity Propagation

    Directory of Open Access Journals (Sweden)

    Zhihan Liu

    2018-01-01

    Full Text Available Car sharing is a type of car rental service, by which consumers rent cars for short periods of time, often charged by hours. The analysis of urban traffic big data is full of importance and significance to determine locations of depots for car-sharing system. Taxi OD (Origin-Destination is a typical dataset of urban traffic. The volume of the data is extremely large so that traditional data processing applications do not work well. In this paper, an optimization method to determine the depot locations by clustering taxi OD points with AP (Affinity Propagation clustering algorithm has been presented. By analyzing the characteristics of AP clustering algorithm, AP clustering has been optimized hierarchically based on administrative region segmentation. Considering sparse similarity matrix of taxi OD points, the input parameters of AP clustering have been adapted. In the case study, we choose the OD pairs information from Beijing’s taxi GPS trajectory data. The number and locations of depots are determined by clustering the OD points based on the optimization AP clustering. We describe experimental results of our approach and compare it with standard K-means method using quantitative and stationarity index. Experiments on the real datasets show that the proposed method for determining car-sharing depots has a superior performance.

  2. Perceptions on efficacy and side effects of conventional depot antipsychotics (CDA) and atypical depot antipsychotics (ADA): Psychiatrists versus patients in Hong Kong.

    Science.gov (United States)

    Tsang, Hector W H; Fong, Mandy W M; Fung, Kelvin M T; Chung, Raymond C K

    2010-03-01

    Abstract Objectives. We compared the satisfaction level of psychiatrists and psychiatric patients towards conventional (CDA) and atypical (ADA) depot antipsychotics on symptom management, role functioning, and side effects. Method. Patients from an out-patient clinic of a public hospital and psychiatrists from public hospitals participated in the survey in 2007-2008. A total of 153 patients were interviewed by a tailor-made questionnaire and 72 psychiatrists self-administered a similar questionnaire. Results. Both groups shared similar attitudes towards clinical effectiveness and treatment efficacy of ADA and CDA. More patients were ambivalent towards relapse prevention of CDA than psychiatrists (30.7 vs. 16.7%, PADA are associated with less side effects. More than half of the patients showed negative attitudes towards the effectiveness of CDA on improving quality of life (52.40%), work (57.50%), and recreation (55.50%). Psychiatrists were more aware of the limitation of CDA and severity of side effects of CDA. They did not, however, seem to incorporate patients' opinions and research findings into their clinical practice. Conclusion. Evidence-based practice and shared decision-making model between clinicians and mental patients should be advocated. More investigations should be devoted to examine the efficacy of ADA as the alternative to CDA.

  3. Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model

    Directory of Open Access Journals (Sweden)

    Wilsey JT

    2018-04-01

    Full Text Available Jared T Wilsey, Julie H Block Medtronic Spine Division, Memphis, TN, USA Background: Previous research suggests that the α2 adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on peripheral pain generators. However, aqueous injections are limited by rapid systemic absorption leading to off target effects and a brief analgesic duration of action. Purpose: The aim of this study was to examine the efficacy of a sustained-release clonidine depot, placed in the wound bed, in a pig incisional pain model. Methods: The depot was a 15 mm ×5 mm ×0.3 mm poly(lactide-co-caprolactone polymer film containing 3% (w/w clonidine HCl (MDT3. Fifty-two young adult mix Landrace pigs (9–11 kg were divided into seven groups. All subjects received a 6 cm, full-thickness, linear incision into the left lateral flank. Group 1 served as a Sham control group (Sham, n=8. Group 2 received three placebo strips (PBO, n=8, placed end-to-end in the subcutaneous wound bed before wound closure. Group 3 received one MDT3 and two PBO (n=8, Group 4 received two MDT3 and one PBO (n=8, and Group 5 received three MDT3 (n=8. Positive control groups received peri-incisional injections of bupivacaine solution (Group 6, 30 mg/day bupivacaine, n=8 or clonidine solution (Group 7, 225 µg/day, n=4. Results: The surgical procedure was associated with significant peri-incisional tactile allodynia. There was a dose-dependent effect of MDT3 in partially reversing the peri-incisional tactile allodynia, with maximum pain relief relative to Sham at 72 hours. Daily injections of bupivacaine (30 mg, but not clonidine (up to 225 µg, completely reversed allodynia within 48 hours. There was a statistically significant correlation between the dose of MDT3 and cumulative withdrawal threshold from 4 hours through the conclusion of the study on day 7. Conclusion: These data suggest that a sustained-release clonidine depot may be a

  4. Sustained analgesic effect of clonidine co-polymer depot in a porcine incisional pain model.

    Science.gov (United States)

    Wilsey, Jared T; Block, Julie H

    2018-01-01

    Previous research suggests that the α 2 adrenergic agonist clonidine, a centrally acting analgesic and antihypertensive, may also have direct effects on peripheral pain generators. However, aqueous injections are limited by rapid systemic absorption leading to off target effects and a brief analgesic duration of action. The aim of this study was to examine the efficacy of a sustained-release clonidine depot, placed in the wound bed, in a pig incisional pain model. The depot was a 15 mm ×5 mm ×0.3 mm poly(lactide-co-caprolactone) polymer film containing 3% (w/w) clonidine HCl (MDT3). Fifty-two young adult mix Landrace pigs (9-11 kg) were divided into seven groups. All subjects received a 6 cm, full-thickness, linear incision into the left lateral flank. Group 1 served as a Sham control group (Sham, n=8). Group 2 received three placebo strips (PBO, n=8), placed end-to-end in the subcutaneous wound bed before wound closure. Group 3 received one MDT3 and two PBO (n=8), Group 4 received two MDT3 and one PBO (n=8), and Group 5 received three MDT3 (n=8). Positive control groups received peri-incisional injections of bupivacaine solution (Group 6, 30 mg/day bupivacaine, n=8) or clonidine solution (Group 7, 225 µg/day, n=4). The surgical procedure was associated with significant peri-incisional tactile allodynia. There was a dose-dependent effect of MDT3 in partially reversing the peri-incisional tactile allodynia, with maximum pain relief relative to Sham at 72 hours. Daily injections of bupivacaine (30 mg), but not clonidine (up to 225 µg), completely reversed allodynia within 48 hours. There was a statistically significant correlation between the dose of MDT3 and cumulative withdrawal threshold from 4 hours through the conclusion of the study on day 7. These data suggest that a sustained-release clonidine depot may be a viable nonopioid, nonamide anesthetic therapy for the treatment of acute postsurgical nociceptive sensitization.

  5. Global adiposity and thickness of intraperitoneal and mesenteric adipose tissue depots are increased in women with polycystic ovary syndrome (PCOS).

    Science.gov (United States)

    Borruel, Susana; Fernández-Durán, Elena; Alpañés, Macarena; Martí, David; Alvarez-Blasco, Francisco; Luque-Ramírez, Manuel; Escobar-Morreale, Héctor F

    2013-03-01

    Sexual dimorphism suggests a role for androgens in body fat distribution. Women with polycystic ovary syndrome (PCOS), a mainly androgen excess disorder, often present with abdominal obesity and visceral adiposity. We hypothesized that women with PCOS have a masculinized body fat distribution favoring the deposition of fat in visceral and organ-specific adipose tissue depots. This was a case-control study. The study was conducted at an academic hospital. Women with PCOS (n = 55), women without androgen excess (n = 25), and men (n = 26) presenting with similar body mass index participated in the study. There were no interventions. Ultrasound measurements of adipose tissue depots including sc (minimum and maximum), preperitoneal, ip, mesenteric, epicardial, and perirenal fat thickness were obtained and total body fat mass was estimated using a body fat monitor. Men and patients with PCOS had increased amounts of total body fat compared with control women. Men had increased thickness of intraabdominal adipose tissue depots compared with the control women, with the women with PCOS showing intermediate values that were also higher than those of control women in the case of ip and mesenteric fat thickness and was close to reaching statistical significance in the case of epicardial fat thickness. Women with PCOS also showed increased minimum sc fat thickness compared with the control women. Obesity increased the thickness of all of the adipose tissue depots in the 3 groups of subjects. Women with PCOS have higher global adiposity and increased amounts of visceral adipose tissue compared with control women, especially in the ip and mesenteric depots.

  6. Inoculation of weaned pigs with E. coli reduces depots of vitamin E

    DEFF Research Database (Denmark)

    Lauridsen, Charlotte; Vestergaard, Ellen-Margrethe; Højsgaard, Søren

    2011-01-01

    This study was designed to investigate the effect of vitamin E supplementation on vitamin E depots and immune responses in weaned pigs after an E. coli inoculation. The design was a 2 × 2 factorial with vitamin E supplementation (150 mg/kg RRR-α-tocopheryl acetate versus a control diet containing...... 60 mg all-rac-α-tocopheryl acetate) and E. coli 0 149 inoculation (inoculation of 1 × 108 CFU on day 2 and 3 after weaning versus inoculation of vehicle). The pigs were housed individually during the experiment which lasted for 10 days from weaning at 7 weeks of age. Blood was sampled on day 1 (day...... of weaning) and 9 of the experiment, and serum was analyzed for α-tocopherol concentration. On day 10 of the experiment, pigs were killed and samples of liver, heart, muscle, adipose tissue and intestinal epithelium were obtained, and immune cells (alveolar macrophages) were harvested, and analyzed for α...

  7. Electrolytic nickel deposits upon uranium; Depot electrolytique de nickel sur l'uraniun

    Energy Technology Data Exchange (ETDEWEB)

    Baudin, G; Chauvin, G; Coriou, H; Hure, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    The authors present a new possibility to protect uranium by very adherent nickel deposits got by aqueous medium electrolysis. Surface treatment of uranium is based upon the chemical etching method from Lietazke. After thermal treatments at 600, 700 and 800 deg. C, under vacuum, a good intermetallic U-Ni diffusion is observed for each case. (author) [French] Les auteurs mettent en evidence une possibilite nouvelle de protection de l'uranium par des depots tres adherents de nickel realises par electrolyse en milieu aqueux. La preparation de surface de l'uranium est basee sur la methode du decapage chimique de Lietazke. Apres des traitements thermiques a 600, 700 et 800 deg. C, sous vide, on constate dans tous les cas une bonne diffusion intermetallique U-Ni. (auteur)

  8. Leuprolide Acetate 1-Month Depot for Central Precocious Puberty: Hormonal Suppression and Recovery

    Directory of Open Access Journals (Sweden)

    Neely EKirk

    2011-01-01

    Full Text Available Methods. This prospective US multicenter trial of leuprolide acetate 1-month depot (7.5–15 mg for central precocious puberty utilized an open-label treatment period, long-term follow-up, and adult callback. Forty-nine females Results. Subjects were treated for years. Mean peak GnRH-stimulated LH and FSH were prepubertal after the first dose and remained suppressed throughout treatment. During treatment, mean estradiol decreased to the limit of detection and mean testosterone decreased but remained above prepubertal norms. During posttreatment follow-up ( years, all patients achieved a pubertal hormonal response within 1 year and menses were reported in all females ≥12 years old. No impairment of reproductive function was observed at adulthood (mean age: 24.8 years.

  9. Improving Inventory Management and Supply Chain of Diesel Fuel in Pertamina 5 Main Depots

    Directory of Open Access Journals (Sweden)

    Togar M Simatupang

    2012-01-01

    Full Text Available Planning Operation subdivision at PT Pertamina has to generate supply decisions includingmain depot to supply, supply point and transportation mode. However, the variability inplanning a supply schedule renders the process of determining a supply decision asineffective. The last assessment on uncertainties was done at 2006 and has not beenconsidered during decision making process. On the other hand, the result of this researchindicates that the uncertainty level is too high to be ignored and the poor informationexchange between the regional offices and the head office decreases the Planning Operation’sability to create plans that covers the company condition. This paper proposes an appropriatesafety stock to withstand the uncertainties and a supply scheduling process that also considersuncertainties by using Monte-Carlo Simulation with random numbers to simulate the events inthe upcoming period.Key words: inventory management, distribution planning, managing uncertainties, montecarlosimulation

  10. Medical Cosmopolitanism in Global Dubai: A Twenty-first-century Transnational Intracytoplasmic Sperm Injection (ICSI) Depot.

    Science.gov (United States)

    Inhorn, Marcia C

    2017-03-01

    Dubai-one of the seven United Arab Emirates and the Middle East's only "global city"-is gaining a reputation as a transnational medical tourism hub. Characterized by its "medical cosmopolitanism," Dubai is now attracting medical travelers from around the world, some of whom are seeking assisted conception. Dubai is fast becoming known as a new transnational "reprohub" for intracytoplasmic sperm injection (ICSI), the variant of in vitro fertilization designed to overcome male infertility. Based on ethnographic research conducted in one of the country's most cosmopolitan clinics, this article explores the ICSI treatment quests of infertile men coming to Dubai from scores of other nations. The case of an infertile British-Moroccan man is highlighted to demonstrate why ICSI is a particularly compelling "masculine hope technology" for infertile Muslim men. Thus, Muslim men who face barriers to ICSI access in their home countries may become "reprotravelers" to Dubai, an emergent ICSI depot. © 2016 by the American Anthropological Association.

  11. Study on Multi-Depot Collaborative Transportation Problem of Milk-Run Pattern

    Directory of Open Access Journals (Sweden)

    Lou Zhenkai

    2016-01-01

    Full Text Available Analyze the relevance between Milk Run mode and collaborative transportation problem, put forward collaborative transportation problem of multiple-depot on Milk Run mode under the supply and demand separate nodes, consider the value of transport and transport costs, introduce the concept of node - arc flow, by comparing the size of traffic flow determine nodes collection, and then constructed multi-transport model of the problem. Considering one-way pickup and delivery closed, construct two-stage algorithm model, use dynamic programming recursive solution to determine the best route to pick up, and then solving delivery routing problem with different start and return point based on geometric method of Cosine. Finally use a numerical example illustrates the effectiveness of the algorithm and reasonable model.

  12. Design of PLGA-based depot delivery systems for biopharmaceuticals prepared by spray drying

    DEFF Research Database (Denmark)

    Wan, Feng; Yang, Mingshi

    2016-01-01

    Currently, most of the approved protein and peptide-based medicines are delivered via conventional parenteral injection (intramuscular, subcutaneous or intravenous). A frequent dosing regimen is often necessary because of their short plasma half-lives, causing poor patient compliance (e.g. pain......, abscess, etc.), side effects owing to typical peak-valley plasma concentration time profiles, and increased costs. Among many sustained-release formulations poly lactic-co-glycolic acid (PLGA)-based depot microparticle systems may represent one of the most promising approaches to provide protein...... and peptide drugs with a steady pharmacokinetic/pharmacodynamic profile maintained for a long period. However, the development of PLGA-based microparticle systems is still impeded by lack of easy, fast, effective manufacturing technologies. The aim of this paper is to review recent advances in spray drying...

  13. Location and multi-depot vehicle routing for emergency vehicles using tour coverage and random sampling

    Directory of Open Access Journals (Sweden)

    Alireza Goli

    2015-09-01

    Full Text Available Distribution and optimum allocation of emergency resources are the most important tasks, which need to be accomplished during crisis. When a natural disaster such as earthquake, flood, etc. takes place, it is necessary to deliver rescue efforts as quickly as possible. Therefore, it is important to find optimum location and distribution of emergency relief resources. When a natural disaster occurs, it is not possible to reach some damaged areas. In this paper, location and multi-depot vehicle routing for emergency vehicles using tour coverage and random sampling is investigated. In this study, there is no need to visit all the places and some demand points receive their needs from the nearest possible location. The proposed study is implemented for some randomly generated numbers in different sizes. The preliminary results indicate that the proposed method was capable of reaching desirable solutions in reasonable amount of time.

  14. Adipose tissue depot volume relationships with spinal trabecular bone mineral density in African Americans with diabetes.

    Directory of Open Access Journals (Sweden)

    Gary C Chan

    Full Text Available Changes in select adipose tissue volumes may differentially impact bone mineral density. This study was performed to assess cross-sectional and longitudinal relationships between computed tomography-determined visceral (VAT, subcutaneous (SAT, inter-muscular (IMAT, and pericardial adipose tissue (PAT volumes with respective changes in thoracic vertebral and lumbar vertebral volumetric trabecular bone mineral density (vBMD in African Americans with type 2 diabetes. Generalized linear models were fitted to test relationships between baseline and change in adipose volumes with change in vBMD in 300 African American-Diabetes Heart Study participants; adjustment was performed for age, sex, diabetes duration, study interval, smoking, hypertension, BMI, kidney function, and medications. Participants were 50% female with mean ± SD age 55.1±9.0 years, diabetes duration 10.2±7.2 years, and BMI 34.7±7.7 kg/m2. Over 5.3 ± 1.4 years, mean vBMD decreased in thoracic/lumbar spine, while mean adipose tissue volumes increased in SAT, IMAT, and PAT, but not VAT depots. In fully-adjusted models, changes in lumbar and thoracic vBMD were positively associated with change in SAT (β[SE] 0.045[0.011], p<0.0001; 0.40[0.013], p = 0.002, respectively. Change in thoracic vBMD was positively associated with change in IMAT (p = 0.029 and VAT (p = 0.016; and change in lumbar vBMD positively associated with baseline IMAT (p<0.0001. In contrast, vBMD was not associated with change in PAT. After adjusting for BMI, baseline and change in volumes of select adipose depots were associated with increases in thoracic and lumbar trabecular vBMD in African Americans. Effects of adiposity on trabecular bone appear to be site-specific and related to factors beyond mechanical load.

  15. Disposal of chemical agents and munitions stored at Umatilla Depot Activity, Hermiston, Oregon

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, G.P.; Hillsman, E.L.; Johnson, R.O.; Miller, R.L.; Patton, T.G.; Schoepfle, G.M.; Tolbert, V.R.; Feldman, D.L.; Hunsaker, D.B. Jr.; Kroodsma, R.L.; Morrissey, J.; Rickert, L.W.; Staub, W.P.; West, D.C.

    1993-02-01

    The Umatilla Depot Activity (UMDA) near Hermiston, Oregon, is one of eight US Army installations in the continental United States where lethal unitary chemical agents and munitions are stored, and where destruction of agents and munitions is proposed under the Chemical Stockpile Disposal Program (CSDP). The chemical agent inventory at UMDA consists of 11.6%, by weight, of the total US stockpile. The destruction of the stockpile is necessary to eliminate the risk to the public from continued storage and to dispose of obsolete and leaking munitions. In 1988 the US Army issued a Final Programmatic Environmental Impact Statement (FPEIS) for the CSDP that identified on-site disposal of agents and munitions as the environmentally preferred alternative (i.e., the alternative with the least potential to cause significant adverse impacts), using a method based on five measures of risk for potential human health and ecosystem/environmental effects; the effectiveness and adequacy of emergency preparedness capabilities also played a key role in the FPEIS selection methodology. In some instances, the FPEIS included generic data and assumptions that were developed to allow a consistent comparison of potential impacts among programmatic alternatives and did not include detailed conditions at each of the eight installations. The purpose of this Phase 1 report is to examine the proposed implementation of on-site disposal at UMDA in light of more recent and more detailed data than those included in the FPEIS. Specifically, this Phase 1 report is intended to either confirm or reject the validity of on-site disposal for the UMDA stockpile. Using the same computation methods as in the FPEIS, new population data were used to compute potential fatalities from hypothetical disposal accidents. Results indicate that onsite disposal is clearly preferable to either continued storage at UMDA or transportation of the UMDA stockpile to another depot for disposal.

  16. Disposal of chemical agents and munitions stored at Anniston Army Depot, Anniston, Alabama

    Energy Technology Data Exchange (ETDEWEB)

    Hunsaker, D.B. Jr.; Zimmerman, G.P.; Hillsman, E.L.; Miller, R.L.; Schoepfle, G.M.; Johnson, R.O.; Tolbert, V.R.; Kroodsma, R.L.; Rickert, L.W.; Rogers, G.O.; Staub, W.P.

    1990-09-01

    The purpose of this Phase I report is to examined the proposed implementation of on-site disposal at Anniston Army Depot (ANAD) in light of more detailed and more recent data than those included in the Final Programmatic Environmental Impact Statement (EPEIS). Two principal issues are addressed: (1) whether or not the new data would result in identification of on-site disposal at ANAD as the environmentally preferred alternative (using the same selection method and data analysis tools as in the FPEIS), and (2) whether or not the new data indicate the presence of significant environmental resources that could be affected by on-site disposal at ANAD. In addition, a status report is presented on the maturity of the disposal technology (and now it could affect on-site disposal at ANAD). Inclusion of these more recent data into the FPEIS decision method resulted in confirmation of on-site disposal for ANAD. No unique resources with the potential to prevent or delay implementation of on-site disposal at ANAD have been identified. A review of the technology status identified four principal technology developments that have occurred since publication of the FPEIS and should be of value in the implementation of on-site disposal at ANAD: the disposal of nonlethal agent at Pine Bluff Arsenal, located near Pine Bluff, Arkansas; construction and testing of facilities for disposal of stored lethal agent at Johnston Atoll, located about 1300 km (800 miles) southwest of Hawaii in the Pacific Ocean; lethal agent disposal tests at the chemical agent pilot plant operations at Tooele Army Depot, located near Salt Lake City, Utah; and equipment advances. 18 references, 13 figs., 10 tabs.

  17. [Job stress in locomotive attendants in a locomotive depot and related influencing factors].

    Science.gov (United States)

    Kang, L; Jia, X C; Lu, F; Zhou, W H; Chen, R

    2017-10-20

    Objective: To investigate the current status of job stress in locomotive attendants in a locomotive depot and related influencing factors. Methods: From 2012 to 2013, cluster sampling was used to select 1500 locomotive attendants in a locomotive depot in Zhengzhou Railway Bureau as respondents.The contents of the investigation included general data and occupational information.A job satisfaction questionnaire was used to investigate the degree of satisfaction, a depression scale was used to investigate the frequency of symptoms, and a daily stress scale was used to investigate the frequency of fatigue and stress. Results: There was a significant difference in depression score between locomotive attendants with different ages, working years, degrees of education, working situations of spouse, total monthly family incomes, numbers of times of attendanceat night, monthly numbers of times of attendance,ormonthly attendance times( P job satisfaction score between locomotive attendants with different ages,working years, degrees of education, working situations of spouse, total monthly family incomes, numbers of times of attendance at night, monthly attendance times,or ways to work( P job satisfaction( β =1.546)and monthly number of times of attendance,working years,attendance time at night,and degree of education were negatively correlated with job satisfaction( β =-0.185,-0.097,-0.020,and -1.106); monthly number of times of attendance andcommute time were positively correlated with depression( β =0.243 and 0.029); attendance time at night,working situation of spouse,commute time,monthly number of times of attendance,degree of education,and working years were positively correlated with daily stress( β =0.006,0.473,0.010,0.043,0.585, and 0.028). Conclusion: Number of times of attendance, attendance time,working years,and spouse are influencing factors for job stress in locomotive attendants. Improvement in work process and care for their personal life help to reduce

  18. Audit Report on the Sacramento Army Depot Internal Review and Audit Compliance Office's "Audits of Warranties, Quality Deficiency Reports, and Reports of Discrepancies"

    National Research Council Canada - National Science Library

    1992-01-01

    The Sacramento Army Depot (SAAD) Internal Review and Audit Compliance Office (Internal Review) issued an audit report, "Audit of Warranties, Quality Deficiency Reports, and Reports of Discrepancies," on July 20, 1990...

  19. Siting Report for Theater Missile Defense Mid-Range Test Launch Complex at Ft. Wingate Depot Activity, NM: Based on Sit Survey, 14-18 February 1994

    National Research Council Canada - National Science Library

    1994-01-01

    This study is provided to assess the capability of Ft. Wingate Depot Activity to act as a Ballistic Missile Defense Test Support Complex for the launch of target missiles toward White Sands Missile Range...

  20. Adesão ao tratamento e hospitalizações entre pacientes que realizam aplicações de Flufenazina Depot Adhesión al tratamiento y hospitalización entre pacientes que realizan aplicaciones de Flufenazina Depot Compliance with treatment and hospitalization among patients using Flufenazine Depot

    Directory of Open Access Journals (Sweden)

    José Menna Oliveira

    2003-08-01

    Full Text Available OBJETIVOS: Os autores revisam a bibliografia sobre medicação depot e apresentam dados referentes à adesão ao tratamento e hospitalizações entre os pacientes que realizam aplicações de enantato de flufenazina em regime ambulatorial no Hospital Espírita de Pelotas. MÉTODO: Analisaram-se os prontuários de pacientes que foram incluídos no regime depot anteriormente a maio de 2001 e que realizaram pelo menos uma aplicação entre maio de 2001 e junho de 2002, quanto à adesão ao tratamento e eventuais hospitalizações. RESULTADOS: De um total de 100 pacientes, 66 permaneciam em regime depot ao término do período estudado. Destes, 40 (61% apresentavam boa adesão ao tratamento, enquanto 26 (39% apresentavam má adesão. Houve um total de 25 pacientes que sofreram hospitalizações, entre os quais a maioria não estava em tratamento no término do estudo ou apresentava má adesão. Entre os pacientes procedentes do mesmo bairro em que se situa o hospital, 10 (67% apresentavam boa adesão em comparação com 30 pacientes (59% procedentes de bairros distintos. DISCUSSÃO: O número de hospitalizações variou visivelmente, conforme a permanência ou não em tratamento e a adesão ao mesmo. Pacientes provenientes de bairros distantes do hospital tenderam a apresentar pior adesão ao tratamento. CONCLUSÕES: É possível que pacientes em regime de aplicação depot residentes próximos ao local de aplicação beneficiem-se mais do tratamento que aqueles residentes em locais distantes. São necessários mais estudos comparando administrações depot com VO em termos de adesão e investigando fatores preditores de boa adesão ao tratamento.OBJETIVOS: Los autores revisan la bibliografía sobre medicación depot y presentan datos referentes a la adhesión al tratamiento y hospitalizaciones entre los pacientes que realizan aplicaciones de enantato de flufenazina en régimen ambulatorio en el Hospital Espiritista de Pelotas. MÉTODO: Fueron

  1. An Analysis of the Factors Generating the Variance Between the Budgeted and Actual Operating Results of the Naval Aviation Depot at North Island, California

    Science.gov (United States)

    2008-06-01

    management structure employs free- market system principles and encourages business-like processes that are mission driven. Since no operating funds are...variable (Potvin, 2007). 2. Unit Cost Goal NWCFs use the unit cost goal ( UCG ) for planning purposes. The UCG is an estimate of what a unit of product...mission 6. Will not interfere with depot performance This section opens the depot to the private market . 53 Chapter 159 – Real Property

  2. Depot-Specific Response of Adipose Tissue to Diet-Induced Inflammation: The Retinoid-Related Orphan Receptor α (RORα) Involved?

    Science.gov (United States)

    Kadiri, Sarah; Auclair, Martine; Capeau, Jacqueline; Antoine, Bénédicte

    2017-11-01

    Epididymal adipose tissue (EAT), a visceral fat depot, is more closely associated with metabolic dysfunction than inguinal adipose tissue (IAT), a subcutaneous depot. This study evaluated whether the nuclear receptor RORα, which controls inflammatory processes, could be implicated. EAT and IAT were compared in a RORα loss-of-function mouse (sg/sg) and in wild-type (WT) littermates, fed a standard diet (SD) or a Western diet (WD), to evaluate the impact of RORα expression on inflammatory status and on insulin sensitivity (IS) of each fat depot according to the diet. Sg/sg mice fed the SD exhibited a decreased inflammatory status and a higher IS in their fat depots than WT mice. WD-induced obesity had distinct effects on the two fat depots. In WT mice, EAT exhibited increased inflammation and insulin resistance while IAT showed reduced inflammation and improved IS, together with a depot-specific increase of RORα, and its target gene IκBα, in the stroma vascular fraction (SVF). Conversely, in sg/sg mice, WD increased inflammation and lowered IS of IAT but not of EAT. These findings suggest an anti-inflammatory role for RORα in response to WD, which occurs at the level of SVF of IAT, thus possibly contributing to the "healthy" expansion of IAT. © 2017 The Obesity Society.

  3. Association between individual fat depots and cardio-metabolic traits in normal- and overweight children, adolescents and adults.

    Science.gov (United States)

    Hübers, M; Geisler, C; Plachta-Danielzik, S; Müller, M J

    2017-05-08

    To determine age-related associations between fat mass (FM), regional fat depots and cardiometabolic traits in normal- and overweight children, adolescents and adults. Detailed body composition (regional subcutaneous and visceral adipose tissue; SAT, VAT) by whole-body magnetic resonance imaging (MRI), FM and fat-free mass by air-displacement plethysmography, systolic and diastolic blood pressure (SBP, DBP), triglycerides (TG), high-density lipoprotein cholesterol (HDL), plasma glucose and plasma insulin were measured in 433 subjects (BMI: 23.6 (21.0-27.7); 151 children and adolescents, aged 6-18 years, 150 young adults, aged 18-30 years and 132 adults, aged 30-60 years). Data were derived from pooled data of the 'Reference Center for Body Composition' in Kiel, Germany. Insulin resistance was determined by the homeostatic model assessment of insulin resistance (HOMA-IR). Partial correlations and multivariate linear regression analyses were used to evaluate the associations between body composition and cardiometabolic traits. A descriptive approach was used to demonstrate age-dependent differences in associations between body fat depots and insulin resistance, independent of BMI. FM, SAT, and VAT increased from childhood to adulthood with low VAT in children and adolescents. When compared to children, TG was higher in adults. HDL and DBP did not differ between age groups. Insulin resistance was highest in male adolescents and female young adults. Associations between body fat depots and cardiometabolic traits were seen after puberty with no associations in pre- and intrapubertal children. When compared to FM, SAT and VAT had the strongest association with insulin resistance in adults. This association was independent of BMI. Associations between individual body fat depots and most cardiometabolic traits became evident after puberty only. The strongest associations were observed between insulin resistance and abdominal fat in adults. The impact of VAT was independent

  4. Randomised controlled single-blind study of conventional versus depot mydriatic drug delivery prior to cataract surgery

    Directory of Open Access Journals (Sweden)

    Madge Simon

    2006-11-01

    Full Text Available Abstract Background A prerequisite for safe cataract surgery is an adequately dilated pupil. The authors conducted a trial to assess the efficacy (in terms of pupil diameter of a depot method of pre-operative pupil dilatation, as compared with repeated instillations of drops (which is time-consuming for the nursing staff and uncomfortable for the patient. Methods A prospective randomised masked trial was conducted comprising 130 patients with no significant ocular history undergoing elective clear corneal phacoemulsification. 65 patients had mydriatic drops (Tropicamide 1%, Phenylephrine 2.5%, Diclofenac sodium 0.1% instilled prior to surgery, 65 had a wick soaked in the same drop mixture placed in the inferior fornix. Horizontal pupil diameters were recorded on a millimetre scale immediately prior to surgery. Results There was no significant difference in pupil size between the two groups (p = 0.255, Student's t-test. Conclusion There was no significant difference between the mydriasis obtained with the depot system compared with conventional drop application. Use of a depot mydriatic delivery system appears to be a safe and efficient method of drug delivery. Trial Registration International Standard Randomised Controlled Trial Number Register ISRCTN78047760

  5. Endurance exercise training induces fat depot-specific differences in basal autophagic activity

    International Nuclear Information System (INIS)

    Tanaka, Goki; Kato, Hisashi; Izawa, Tetsuya

    2015-01-01

    The purpose of this study was to uncover the effect of exercise training on the expression of autophagy marker proteins in epididymal white adipose tissue (eWAT), inguinal WAT (iWAT), and the stromal vascular fraction (SVF) collected from eWAT. Male Wistar rats aged 4–5 weeks were randomly divided into two groups, sedentary control (n = 7) and exercise-trained (n = 7). Rats in the exercise-trained group were exercised on a treadmill set at a 5° incline 5 days/week for 9 weeks. We determined that the expression levels of an autophagosome-associating form of microtubule-associated protein 1 light chain 3 (LC3)-II and of p62 were significantly higher in eWAT from exercise-trained than from control rats, while those of adipose-specific deletion of autophagy-related protein (ATG7) and lysosomal-associated membrane protein type 2A (LAMP2a) showed no difference between groups. However, in iWAT, the expression levels of LC3-II and ATG7 were significantly higher in exercise-trained than in control rats. The expression of p62 was highly correlated with that of peroxisome proliferator-activated receptor γ (PPARγ), a master regulator of adipogenesis and lipid metabolism, in both WAT types (eWAT, r = 0.856, P < 0.05; iWAT, r = 0.762, P < 0.05), whereas LC3-II and PPARγ levels were highly correlated in eWAT (r = 0.765, P < 0.05) but not in iWAT (r = −0.306, ns). In SVF, the expression levels of LC3II, ATG7, and LAMP2a were significantly higher in exercise-trained than in control rats. These results suggest that exercise training suppresses basal autophagy activity in eWAT, but that this activity is enhanced in iWAT and SVF collected from eWAT. Thus, the adaptation of basal autophagic activity following exercise training exhibits fat depot-specific differences. - Highlights: • Autophagy has been associated with obesity and associated diseases. • We examined exercise-associated rat white adipose tissue (WAT) autophagy markers. • Exercise increased

  6. Endurance exercise training induces fat depot-specific differences in basal autophagic activity

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Goki; Kato, Hisashi; Izawa, Tetsuya, E-mail: tizawa@mail.doshisha.ac.jp

    2015-10-23

    The purpose of this study was to uncover the effect of exercise training on the expression of autophagy marker proteins in epididymal white adipose tissue (eWAT), inguinal WAT (iWAT), and the stromal vascular fraction (SVF) collected from eWAT. Male Wistar rats aged 4–5 weeks were randomly divided into two groups, sedentary control (n = 7) and exercise-trained (n = 7). Rats in the exercise-trained group were exercised on a treadmill set at a 5° incline 5 days/week for 9 weeks. We determined that the expression levels of an autophagosome-associating form of microtubule-associated protein 1 light chain 3 (LC3)-II and of p62 were significantly higher in eWAT from exercise-trained than from control rats, while those of adipose-specific deletion of autophagy-related protein (ATG7) and lysosomal-associated membrane protein type 2A (LAMP2a) showed no difference between groups. However, in iWAT, the expression levels of LC3-II and ATG7 were significantly higher in exercise-trained than in control rats. The expression of p62 was highly correlated with that of peroxisome proliferator-activated receptor γ (PPARγ), a master regulator of adipogenesis and lipid metabolism, in both WAT types (eWAT, r = 0.856, P < 0.05; iWAT, r = 0.762, P < 0.05), whereas LC3-II and PPARγ levels were highly correlated in eWAT (r = 0.765, P < 0.05) but not in iWAT (r = −0.306, ns). In SVF, the expression levels of LC3II, ATG7, and LAMP2a were significantly higher in exercise-trained than in control rats. These results suggest that exercise training suppresses basal autophagy activity in eWAT, but that this activity is enhanced in iWAT and SVF collected from eWAT. Thus, the adaptation of basal autophagic activity following exercise training exhibits fat depot-specific differences. - Highlights: • Autophagy has been associated with obesity and associated diseases. • We examined exercise-associated rat white adipose tissue (WAT) autophagy markers. • Exercise increased

  7. Depot injectable atorvastatin biodegradable in situ gel: development, optimization, in vitro, and in vivo evaluation

    Directory of Open Access Journals (Sweden)

    Ahmed TA

    2016-01-01

    Full Text Available Tarek A Ahmed,1,2 Yasser A Alharby,1 Abdel-Rahim M El-Helw,1 Khaled M Hosny,1,3 Khalid M El-Say1,21Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt; 3Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni Suef University, Beni Suef, EgyptAbstract: This study aimed to develop an optimized depot injectable atorvastatin (ATR biodegradable in situ gel (ISG system with minimum initial burst using a central composite design. The factors selected were poly (D, L-lactide-co-glycolide (PLGA concentration (X1, molecular weight of polyethylene glycol (PEG (X2, and PEG concentration (X3. The independent variables were the initial burst of ATR after 2 (Y1 and 24 hours (Y2. The optimized formulation was investigated using scanning electron microscopy, Fourier transform infrared spectroscopy, and in vitro drug release in phosphate-buffered saline of pH 7.4 for 72 hours. The in vivo pharmacokinetic study of the optimized ATR-ISG and the corresponding PEG-free ATR-ISG were conducted by intramuscular injection of a single dose (2 mg/kg of ATR in male New Zealand White rabbits. A double-blind, randomized, parallel design was used in comparison with those of the marketed ATR tablet. Statistical analysis revealed that PLGA concentration and the molecular weight of PEG have pronounced effects on both Y1 and Y2. The optimized formulation was composed of 36.10% PLGA, PEG 6000, and 15.69% PEG, and exhibited characteristic in vitro release pattern with minimal initial burst. Incorporation of PEG in the formulation causes a slight decrease in the glass transition temperature value of PLGA, leading to a slight change in Fourier transform infrared spectroscopy spectrum due to possible interaction. Moreover, scanning electron microscopy photomicrograph showed smooth

  8. Campaign for Fairness : backgrounder. 3 ed.

    International Nuclear Information System (INIS)

    2001-01-01

    The people of Nova Scotia want to develop the strengths offered by offshore petroleum resources in order to build a secure future for themselves through a strong, vital economy that will provide jobs and opportunities. They also want to have access to quality public services at levels of taxation comparable to other jurisdictions. The Campaign for Fairness will give them the tool to accomplish their goals. The government of Nova Scotia is seeking an adjustment from the federal government of the imbalance between the federal and provincial benefits from offshore oil and gas development. Federal-provincial agreements dating back to 1982 and 1986 named Nova Scotia as the main beneficiary of offshore benefits. The intent of this decision was to give Nova Scotia the opportunity to create a strong economy using offshore petroleum resources. However, recent calculations by the Nova Scotia Department of Finance have shown that the federal government will receive about 80 per cent of the royalties and other revenues associated with offshore petroleum development. Nova Scotia is proposing that the federal government should recognize the province as the main beneficiary of petroleum development in its offshore according to the agreements signed in the 1980s. Nova Scotia also wants to ensure that future economic prospects are linked to provincial resources and initiative and not to dependence on federal equalization transfers. 3 figs

  9. Prompt Gamma Activation Analysis of the Nyírlugos obsidian core depot find

    Directory of Open Access Journals (Sweden)

    Zsolt Kasztovszky

    2014-03-01

    Full Text Available The Nyírlugos obsidian core depot find is one of the most important lithic assemblages in the collection of the Hungarian National Museum (HNM. The original set comprised 12 giant obsidian cores, of which 11 are currently on the permanent archaeological exhibition of the HNM. One of the cores is known to be inDebrecen. The first publication attributed the hoard, on the strength of giant (flint blades known from the Early and Middle Copper Age Tiszapolgár and Bodrogkeresztúr cultures, to the Copper Age. In the light of recent finds it is more likely to belong to the Middle Neolithic period. The source area was defined as Tokaj Mts., about100 kmto the NW from Nyírlugos. The size and beauty of the exceptional pieces exclude any invasive analysis. Using Prompt Gamma Activation Analysis (PGAA, we can measure major chemical components and some key trace elements of stone artefacts with adequate accuracy to successfully determine provenance of obsidian. Recent methodological development also facilitated the study of relatively large objects like the Nyírlugos cores. The cores were individually measured by PGAA. The results show that the cores originate from the Carpathian 1 sources, most probably the Viničky variety (C1b. The study of the hoard as a batch is an important contribution to the assessment of prehistoric trade and allows us to reconsider the so-called Carpathian, especially Carpathian 1 (Slovakian sources.

  10. Enhanced intelligent water drops algorithm for multi-depot vehicle routing problem.

    Science.gov (United States)

    Ezugwu, Absalom E; Akutsah, Francis; Olusanya, Micheal O; Adewumi, Aderemi O

    2018-01-01

    The intelligent water drop algorithm is a swarm-based metaheuristic algorithm, inspired by the characteristics of water drops in the river and the environmental changes resulting from the action of the flowing river. Since its appearance as an alternative stochastic optimization method, the algorithm has found applications in solving a wide range of combinatorial and functional optimization problems. This paper presents an improved intelligent water drop algorithm for solving multi-depot vehicle routing problems. A simulated annealing algorithm was introduced into the proposed algorithm as a local search metaheuristic to prevent the intelligent water drop algorithm from getting trapped into local minima and also improve its solution quality. In addition, some of the potential problematic issues associated with using simulated annealing that include high computational runtime and exponential calculation of the probability of acceptance criteria, are investigated. The exponential calculation of the probability of acceptance criteria for the simulated annealing based techniques is computationally expensive. Therefore, in order to maximize the performance of the intelligent water drop algorithm using simulated annealing, a better way of calculating the probability of acceptance criteria is considered. The performance of the proposed hybrid algorithm is evaluated by using 33 standard test problems, with the results obtained compared with the solutions offered by four well-known techniques from the subject literature. Experimental results and statistical tests show that the new method possesses outstanding performance in terms of solution quality and runtime consumed. In addition, the proposed algorithm is suitable for solving large-scale problems.

  11. Active motions of Brownian particles in a generalized energy-depot model

    International Nuclear Information System (INIS)

    Zhang Yong; Koo Kim, Chul; Lee, Kong-Ju-Bock

    2008-01-01

    We present a generalized energy-depot model in which the rate of conversion of the internal energy into motion can be dependent on the position and velocity of a particle. When the conversion rate is a general function of the velocity, the active particle exhibits diverse patterns of motion, including a braking mechanism and a stepping motion. The phase trajectories of the motion are investigated in a systematic way. With a particular form of the conversion rate dependent on the position and velocity, the particle shows a spontaneous oscillation characterizing a negative stiffness. These types of active behaviors are compared with similar phenomena observed in biology, such as the stepping motion of molecular motors and amplification in the hearing mechanism. Hence, our model can provide a generic understanding of the active motion related to the energy conversion and also a new control mechanism for nano-robots. We also investigate the effect of noise, especially on the stepping motion, and observe random walk-like behavior as expected.

  12. ANALISIS HIGIENE SANITASI DEPOT AIR MINUM ISI ULANG (DAMIU DI SEKITAR UNIVERSITAS ISLAM RIAU

    Directory of Open Access Journals (Sweden)

    Fitri Mairizki

    2017-10-01

    Full Text Available The existence of Drinking Water Refill Depot (DAMIU continues to increase appropriate with the dynamics of community needs for drinking water that has good quality and safe for consumption. Although it had a low price, not all DAMIU product guaranteed safety. DAMIU  as  an alternative choice to fulfill the community needs for drinking water becomes a risk that harmful to health if consumers did  not pay attention in DAMIU hygiene and sanitation. Therefore, the purpose of this study was to analyze hygiene and sanitation of  DAMIU building, equipment and operator. The type of this research was descriptive research.The data obtained in this study was primary data in the form of observation using checklist sheet. The data was presented in tabular form and discussed descriptively. In general, hygiene and sanitation of DAMIU building and equipment were good but the sanitation facilities still minimals, the wash basin for operators and its tools were not available. There were  several of operators hygiene must be considered. All operators did not using special uniform for work, did not conducting periodic medical examinations and did not have sertificate of hygiene sanitation course.

  13. RISK MANAGEMENT AND RISK COMMUNICATION IN MOZAMBIQUE: THE CASE OF ARMS AND AMMUNITION DEPOTS OF MALHAZINE

    Directory of Open Access Journals (Sweden)

    Luca Bussotti

    2017-12-01

    Full Text Available Risk management and risk communication affect everybody’s daily life. Local authorities have the duty to manage public structures, to inform civilians of the risks coming from these structures, to implement prophylaxis procedures. Military storage sites are fully included in this category. This article presents – through a qualitative methodology based on risk analysis – how risk management and communication in weapons and ammunition warehouses is managed in a “partially free” country, using as a case-study, the Malhazine depot in Mozambique, which resulted in more than 100 deaths. In 2007, an extraordinary accident related to the management of obsolete conventional weapons occurred at the Malazhine warehouse. In this circumstance, the Mozambican Government adopted a policy of classifying the information “highly confidential”. This policy aimed at obscuring facts and responsibilities by hiding the causes of such a huge tragedy. This article concludes with the consideration that a high level of confidentiality in treating issues of public interest, such as the one kept in regard to Malhazine, does not help public authorities to effectively manage and prevent similar risks from occurring again, with resulting negative impacts on local populations.

  14. Scaling up depot medroxyprogesterone acetate (DMPA): a systematic literature review illustrating the AIDED model.

    Science.gov (United States)

    Curry, Leslie; Taylor, Lauren; Pallas, Sarah Wood; Cherlin, Emily; Pérez-Escamilla, Rafael; Bradley, Elizabeth H

    2013-08-02

    Use of depot medroxyprogesterone acetate (DMPA), often known by the brand name Depo-Provera, has increased globally, particularly in multiple low- and middle-income countries (LMICs). As a reproductive health technology that has scaled up in diverse contexts, DMPA is an exemplar product innovation with which to illustrate the utility of the AIDED model for scaling up family health innovations. We conducted a systematic review of the enabling factors and barriers to scaling up DMPA use in LMICs. We searched 11 electronic databases for academic literature published through January 2013 (n = 284 articles), and grey literature from major health organizations. We applied exclusion criteria to identify relevant articles from peer-reviewed (n = 10) and grey literature (n = 9), extracting data on scale up of DMPA in 13 countries. We then mapped the resulting factors to the five AIDED model components: ASSESS, INNOVATE, DEVELOP, ENGAGE, and DEVOLVE. The final sample of sources included studies representing variation in geographies and methodologies. We identified 15 enabling factors and 10 barriers to dissemination, diffusion, scale up, and/or sustainability of DMPA use. The greatest number of factors were mapped to the ASSESS, DEVELOP, and ENGAGE components. Findings offer early empirical support for the AIDED model, and provide insights into scale up of DMPA that may be relevant for other family planning product innovations.

  15. Light Control of Insulin Release and Blood Glucose Using an Injectable Photoactivated Depot.

    Science.gov (United States)

    Sarode, Bhagyesh R; Kover, Karen; Tong, Pei Y; Zhang, Chaoying; Friedman, Simon H

    2016-11-07

    In this work we demonstrate that blood glucose can be controlled remotely through light stimulated release of insulin from an injected cutaneous depot. Human insulin was tethered to an insoluble but injectable polymer via a linker, which was based on the light cleavable di-methoxy nitrophenyl ethyl (DMNPE) group. This material was injected into the skin of streptozotocin-treated diabetic rats. We observed insulin being released into the bloodstream after a 2 min trans-cutaneous irradiation of this site by a compact LED light source. Control animals treated with the same material, but in which light was blocked from the site, showed no release of insulin into the bloodstream. We also demonstrate that additional pulses of light from the light source result in additional pulses of insulin being absorbed into circulation. A significant reduction in blood glucose was then observed. Together, these results demonstrate the feasibility of using light to allow for the continuously variable control of insulin release. This in turn has the potential to allow for the tight control of blood glucose without the invasiveness of insulin pumps and cannulas.

  16. Behavior of Particle Depots in Molten Silicon During Float-Zone Growth in Strong Magnetic Fields

    Science.gov (United States)

    Jauss, T.; Croell, A.; SorgenFrei, T.; Azizi, M.; Reimann, C.; Friedrich, J.; Volz, M. P.

    2014-01-01

    Solar cells made from directionally solidified silicon cover 57% of the photovoltaic industry's market [1]. One major issue during directional solidification of silicon is the precipitation of foreign phase particles. These particles, mainly SiC and Si3N4, are precipitated from the dissolved crucible coating, which is made of silicon nitride, and the dissolution of carbon monoxide from the furnace atmosphere. Due to their hardness and size of several hundred micrometers, those particles can lead to severe problems during the wire sawing process for wafering the ingots. Additionally, SiC particles can act as a shunt, short circuiting the solar cell. Even if the particles are too small to disturb the wafering process, they can lead to a grit structure of silicon micro grains and serve as sources for dislocations. All of this lowers the yield of solar cells and reduces the performance of cells and modules. We studied the behaviour of SiC particle depots during float-zone growth under an oxide skin, and strong static magnetic fields. For high field strengths of 3T and above and an oxide layer on the sample surface, convection is sufficiently suppressed to create a diffusive like regime, with strongly dampened convection [2, 3]. To investigate the difference between atomically rough phase boundaries and facetted growth, samples with [100] and [111] orientation were processed.

  17. Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise

    Directory of Open Access Journals (Sweden)

    Yang Rongze

    2011-10-01

    Full Text Available Abstract Background Alterations of endocannabinoid system in adipose tissue play an important role in lipid regulation and metabolic dysfunction associated with obesity. The purpose of this study was to determine whether gene expression levels of cannabinoid type 1 receptor (CB1 and fatty acid amide hydrolase (FAAH are different in subcutaneous abdominal and gluteal adipose tissue, and whether hypocaloric diet and aerobic exercise influence subcutaneous adipose tissue CB1 and FAAH gene expression in obese women. Methods Thirty overweight or obese, middle-aged women (BMI = 34.3 ± 0.8 kg/m2, age = 59 ± 1 years underwent one of three 20-week weight loss interventions: caloric restriction only (CR, N = 9, caloric restriction plus moderate-intensity aerobic exercise (CRM, 45-50% HRR, N = 13, or caloric restriction plus vigorous-intensity aerobic exercise (CRV, 70-75% HRR, N = 8. Subcutaneous abdominal and gluteal adipose tissue samples were collected before and after the interventions to measure CB1 and FAAH gene expression. Results At baseline, FAAH gene expression was higher in abdominal, compared to gluteal adipose tissue (2.08 ± 0.11 vs. 1.78 ± 0.10, expressed as target gene/β-actin mRNA ratio × 10-3, P Conclusions There are depot differences in subcutaneous adipose tissue endocannabinoid system gene expression in obese individuals. Aerobic exercise training may preferentially modulate abdominal adipose tissue endocannabinoid-related gene expression during dietary weight loss. Trial Registration ClinicalTrials.gov: NCT00664729.

  18. A comparative study of Cyclofem and depot medroxyprogesterone acetate (DMPA) effects on endometrial vasculature.

    Science.gov (United States)

    Simbar, Masoumeh; Tehrani, Fahimeh Ramezani; Hashemi, Zeinab; Zham, Hananeh; Fraser, Ian S

    2007-10-01

    The most common reason for discontinuation of long-acting progestogen-only contraceptives is irregular bleeding following local endometrial vascular changes. To reduce unpredictable bleeding episodes among depot medroxyprogesterone acetate (DMPA) users, the combined injectable contraceptive, Cyclofem, was offered as an alternative. However, there is a gap in our knowledge about the effects of Cyclofem on the endometrial vasculature and patterns of bleeding. This study aimed to compare the effects of Cyclofem and DMPA on endometrial vascular density, endometrial histology and pattern of bleeding. Sixty-eight healthy women with regular menstrual bleeding and seeking injectable long-acting contraceptives were recruited. Two endometrial samples (before and 3 to 6 months after initial exposure to DMPA or Cyclofem) were collected from each participant. The samples were stained using an immunohistochemical method and anti-CD34 to visualise the endometrial vasculature. Endometrial vascular density was assessed using standard techniques. Sixty-eight women were randomly assigned to Cyclofem (38 women) or DMPA (30 women). Endometrial vascular density was 149.3 +/- 6.7 (mean +/- SD)/mm(2) before injection. This significantly decreased to 132.4 +/- 12.2 after DMPA use, and from 151.9 +/- 5.8 to 131.8 +/- 12.8 vessels/mm(2) following Cyclofem use (paired t-test, p Spotting was the most common type of bleeding experienced, and atrophic endometrium was the most common histological pattern observed in both groups. This study demonstrated that both Cyclofem and DMPA use are associated with decreased endometrial vascular density and atrophic endometrium, in addition to irregular bleeding, mainly spotting. There was no significant difference in bleeding patterns or endometrial findings observed for these two injectable contraceptives in Iranian women.

  19. IGFBP4 Is Required for Adipogenesis and Influences the Distribution of Adipose Depots.

    Science.gov (United States)

    Maridas, David E; DeMambro, Victoria E; Le, Phuong T; Mohan, Subburaman; Rosen, Clifford J

    2017-10-01

    Insulinlike growth factor (IGF) I induces adipogenesis in vitro. IGF-binding protein 4 (IGFBP4) is highly expressed in adipocytes and osteoblasts and is inhibitory of IGFs in vitro. We previously reported that Igfbp4 null mice (Igfbp4-/-) had decreased fat proportions at 8 and 16 weeks of age. However, the mechanism leading to the reduced adiposity remains unknown. The purpose of this study was to elucidate how IGFBP4 mediates adipose tissue development in vivo. Our results showed that inguinal and gonadal white adipose tissue (gWAT) from Igfbp4-/- mice had decreased weights and Pparγ expression. Cultures of primary bone marrow stromal cells (BMSCs) and ear mesenchymal stem cells (eMSCs) from mutant mice showed reduced adipogenesis. Both BMSCs and eMSC had a strong induction of Igfbp4 expression during adipogenesis. Furthermore, the increase in phosphorylated Akt (p-Akt), a downstream target of IGF-I signaling, in wild-type cells, was blunted in mutant eMSCs. On a high-fat diet (HFD) there were sexual differences in adipocyte expansion of Igfbp4-/- mice. Mutant males gained weight by expanding their white fat depots. However, Igfbp4-/- female mice were protected against diet-induced obesity. Ovariectomized Igfbp4-/- female mice gained weight in a manner similar to that seen in ovariectomized controls. Thus, Igfbp4 is required for inguinal fat expansion in female mice but not in male mice. However, gWAT expansion, which is prevented by estrogen during HFD, does not require Igfbp4. Copyright © 2017 Endocrine Society.

  20. Depot-Specific Changes in Fat Metabolism with Aging in a Type 2 Diabetic Animal Model.

    Science.gov (United States)

    Park, Se Eun; Park, Cheol-Young; Choi, Jung Mook; Chang, Eugene; Rhee, Eun-Jung; Lee, Won-Young; Oh, Ki Won; Park, Sung Woo; Kang, Eun Seok; Lee, Hyun Chul; Cha, Bong Soo

    2016-01-01

    Visceral fat accretion is a hallmark of aging and is associated with aging-induced metabolic dysfunction. PPARγ agonist was reported to improve insulin sensitivity by redistributing fat from visceral fat to subcutaneous fat. The purpose of this study was to investigate the underlying mechanisms by which aging affects adipose tissue remodeling in a type 2 diabetic animal model and through which PPARγ activation modulates aging-related fat tissue distribution. At the ages of 21, 31 and 43 weeks, OLETF rats as an animal model of type 2 diabetes were evaluated for aging-related effects on adipose tissue metabolism in subcutaneous and visceral fat depots. During aging, the ratio of visceral fat weight to subcutaneous fat weight (V/S ratio) increased. Aging significantly increased the mRNA expression of genes involved in lipogenesis such as lipoprotein lipase, fatty acid binding protein aP2, lipin 1, and diacylglycerol acyltransferase 1, which were more prominent in visceral fat than subcutaneous fat. The mRNA expression of adipose triglyceride lipase, which is involved in basal lipolysis and fatty acid recycling, was also increased, more in visceral fat compared to subcutaneous fat during aging. The mRNA levels of the genes associated with lipid oxidation were increased, whereas the mRNA levels of genes associated with energy expenditure showed no significant change during aging. PPARγ agonist treatment in OLETF rats resulted in fat redistribution with a decreasing V/S ratio and improved glucose intolerance. The genes involved in lipogenesis decreased in visceral fat of the PPARγ agonist-treated rats. During aging, fat distribution was changed by stimulating lipid uptake and esterification in visceral fat rather than subcutaneous fat, and by altering the lipid oxidation.

  1. Depot-Specific Changes in Fat Metabolism with Aging in a Type 2 Diabetic Animal Model.

    Directory of Open Access Journals (Sweden)

    Se Eun Park

    Full Text Available Visceral fat accretion is a hallmark of aging and is associated with aging-induced metabolic dysfunction. PPARγ agonist was reported to improve insulin sensitivity by redistributing fat from visceral fat to subcutaneous fat. The purpose of this study was to investigate the underlying mechanisms by which aging affects adipose tissue remodeling in a type 2 diabetic animal model and through which PPARγ activation modulates aging-related fat tissue distribution. At the ages of 21, 31 and 43 weeks, OLETF rats as an animal model of type 2 diabetes were evaluated for aging-related effects on adipose tissue metabolism in subcutaneous and visceral fat depots. During aging, the ratio of visceral fat weight to subcutaneous fat weight (V/S ratio increased. Aging significantly increased the mRNA expression of genes involved in lipogenesis such as lipoprotein lipase, fatty acid binding protein aP2, lipin 1, and diacylglycerol acyltransferase 1, which were more prominent in visceral fat than subcutaneous fat. The mRNA expression of adipose triglyceride lipase, which is involved in basal lipolysis and fatty acid recycling, was also increased, more in visceral fat compared to subcutaneous fat during aging. The mRNA levels of the genes associated with lipid oxidation were increased, whereas the mRNA levels of genes associated with energy expenditure showed no significant change during aging. PPARγ agonist treatment in OLETF rats resulted in fat redistribution with a decreasing V/S ratio and improved glucose intolerance. The genes involved in lipogenesis decreased in visceral fat of the PPARγ agonist-treated rats. During aging, fat distribution was changed by stimulating lipid uptake and esterification in visceral fat rather than subcutaneous fat, and by altering the lipid oxidation.

  2. CHAWS user`s guide: System description and standard operating procedures, Lexington-Blue Grass Army Depot

    Energy Technology Data Exchange (ETDEWEB)

    Martins, S.A.; Shinn, J.H. [eds.

    1993-05-01

    The Chemical Hazard Warning System (CHAWS) is designed to collect meteorological data and to display, in real time, the dispersion of hazardous chemicals that may result from an accidental release. Meteorological sensors have been placed strategically around the Lexington-Blue Grass Army Depot and are used to calculate direction and hazard distance for the release. Based on these data, arrows depicting the release direction and distance traveled are graphically displayed on a computer screen showing a site map of the facility. The objectives of CHAWS are as follows: To determine the trajectory of the center of mass of released material from the measured wind field; to calculate the dispersion of the released material based on the measured lateral turbulence intensity (sigma theta); to determine the height of the mixing zone by measurement of the inversion height and wind profiles up to an altitude of about 1 km at sites that have SODAR units installed; to archive meteorological data for potential use in climatological descriptions for emergency planning; to archive air-quality data for preparation of compliance reports; and to provide access to the data for near real time hazard analysis purposes. CHAWS sites are located at the Pine Bluff Arsenal, Arkansas, Edgewood area of Aberdeen Proving Ground, Maryland, Tooele Depot, Utah, Lexington-Blue Grass Depot, Kentucky, and Johnston Island in the Pacific. The systems vary between sites with different features and various types of hardware. The basic system, however, is the same. Nonetheless, we have tailored the manuals to the equipment found at each site.

  3. [French Society for Biological Psychiatry and Neuropsychopharmacology task force: Formal Consensus for the prescription of depot antipsychotics].

    Science.gov (United States)

    Samalin, L; Abbar, M; Courtet, P; Guillaume, S; Lancrenon, S; Llorca, P-M

    2013-12-01

    Compliance is often partial with oral antipsychotics and underestimated for patients with serious mental illness. Despite their demonstrated advantages in terms of relapse prevention, depot formulations are still poorly used in routine. As part of a process to improve the quality of care, French Association for Biological Psychiatry and Neuropsychopharmacology (AFPBN) Task Force elaborated a Formal Consensus for the prescription of depot antipsychotics in clinical practice. The Task Force recommends as first-line choice, the use of long-acting injectable (LAI) second-generation antipsychotics in patients with schizophrenia, schizoaffective disorder and delusional disorder. They can be considered as a second-line option as a monotherapy to prevent manic recurrence or in combination with mood stabilizer to prevent depressive recurrence in the maintenance treatment of bipolar disorder. LAI second-generation antipsychotics can also be used after a first episode of schizophrenia. Depot neuroleptics are not recommended during the early course of schizophrenia and are not appropriate in bipolar disorder. They are considered as a second-line option for maintenance treatment in schizophrenia. LAI formulations should be systematically proposed to any patients for whom maintenance antipsychotic treatment is indicated. LAI antipsychotics can be used preferentially for non-compliant patients with frequent relapses or aggressive behaviors. A specific information concerning the advantages and inconveniences of the LAI formulations, in the framework of shared-decision making must be delivered to each patient. Recommendations for switching from one oral/LAI form to another LAI and for using LAI antipsychotics in specific populations (pregnant women, elderly patients, subjects in a precarious situation, and subjects having to be treated in a prison establishment) are also proposed. Copyright © 2013 L’Encéphale. Published by Elsevier Masson SAS.. All rights reserved.

  4. Treatment of central precocious puberty by subcutaneous injections of leuprorelin 3-month depot (11.25 mg).

    Science.gov (United States)

    Carel, Jean-Claude; Lahlou, Najiba; Jaramillo, Orlando; Montauban, Vincent; Teinturier, Cécile; Colle, Michel; Lucas, Christel; Chaussain, Jean Louis

    2002-09-01

    Depot GnRH agonists are widely used for the treatment of precocious puberty. Leuprorelin 3-month depot is currently used in adults but has not been evaluated in children. We evaluated the efficacy of this new formulation (11.25 mg every 3 months), for the suppression of gonadotropic activation and pubertal signs in children with central precocious puberty. We included 44 children (40 girls) with early-onset pubertal development in a 6-month open trial. The inclusion criteria were clinical pubertal development before the age of 8 (girls) or 10 (boys), advanced bone age, enlarged uterus (>36 mm), testosterone more than 1.7 nmol/liter (boys), and pubertal response of LH to GnRH (peak >5 IU/liter). The principal criterion for efficacy assessment, GnRH-stimulated LH peak less than 3 IU/liter, was met in 81 of 85 (95%) of the tests performed at months 3 and 6. The remaining four values were slightly above the threshold. The levels of sex steroids were also significantly reduced and clinical pubertal development was arrested. Plasma leuprorelin levels, measured every 30 d, were essentially stable after d 60. Local intolerance was noted after 10 of 86 injections (12%), and was mild in four cases, moderate in five cases, and severe in one. Among these 10 events, 4 consisted in local pain at injection's site. In conclusion, leuprorelin 3-month depot efficiently inhibits the gonadotropic axis in 95% of children with central precocious puberty studied for a 6-month period. This regimen allows the reduction of the number of yearly injections from 12 to 4.

  5. A comparative study of cross sectional anatomy and computer tomography of perirenal fat depots in New Zealand White rabbits

    International Nuclear Information System (INIS)

    Yonkova, P.; Dimitrov, R.; Toneva, J.; Zapryanova, D.

    2010-01-01

    CT is a contemporary non-invasive imaging technique that gains an increasing importance for in vivo investigations of subcutaneous and visceral fat. The purpose of this investigation was to describe the topography and anatomy imaging features of perirenal fat depots at the level of both kidneys in clinically healthy New Zealand White rabbits that attained slaughter weight. The CT consecutive transverse scans from the last thoracic to the fifth lumbar vertebrae showed that in rabbits, perirenal fat appeared as a homogeneous hypodense structure at the background of denser shadows of lumbar and abdominal muscles, kidneys and abdominal organs. Perirenal fat depot exhibited a soft tissue density with average attenuation of −120.97±4.73 HU. On CT scans, the largest dimensions of the perirenal fat depot were 1.3±0.01 cm at the level of the right kidneys cranial pole; 1.96 cm in the plane where the right renal hilus was visualized; 1.66±0.08 cm at the level of the right kidneys caudal pole; 1.10±0.18 cm in the plane where the left renal hilus was visualized and 1.06±0.15 cm at the level of the left kidneys caudal pole. No subcutaneous fat deposits in the abdominal area were seen. Results obtained in the present study could be used as basic information for various anatomy investigations of rabbits as well as experimental designs for study of obesity in animals and humans. (author)

  6. Feasibility Study of Economics and Performance of Wind Turbine Generators at the Newport Indiana Chemical Depot Site

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Joseph Owen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mosey, Gail [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-11-01

    The U.S. Environmental Protection Agency (EPA), in accordance with the RE-Powering America's Land initiative, selected the Newport Indiana Chemical Depot site in Newport, Indiana, for a feasibility study of renewable energy production. The National Renewable Energy Laboratory (NREL) was contacted to provide technical assistance for this project. The purpose of this report is to assess the sitefor possible wind turbine electrical generator installation and estimate the cost, performance, and site impacts of different wind energy options. In addition, the report recommends financing options that could assist in the implementation of a wind system at the site.

  7. Desaturation of skeletal muscle structural and depot lipids in obese individuals during a very-low-calorie diet intervention

    DEFF Research Database (Denmark)

    Haugaard, Steen B; Vaag, Allan; Høy, Carl-Erik

    2007-01-01

    would decrease saturated fatty acids (FAs) and increase long-chain polyunsaturated FAs (LCPUFAs) in muscular structural lipids, as such changes have been associated with improved insulin sensitivity. RESEARCH METHODS AND PROCEDURES: Skeletal muscle biopsies (vastus lateralis) were obtained from 13 obese...... during the VLCD. DISCUSSION: Desaturation of both muscle cell membrane phospholipid and IMTG was significant but modest during a VLCD in obese subjects. Further research must delineate whether such changes in skeletal muscle structural and depot lipid composition themselves are enough to promote...

  8. Desaturation of skeletal muscle structural and depot lipids in obese individuals during a very-low-calorie diet intervention

    DEFF Research Database (Denmark)

    Haugaard, S.B.; Vaag, A.; Høy, Carl-Erik

    2007-01-01

    would decrease saturated fatty acids (FAs) and increase long-chain polyunsaturated FAs (LCPUFAs) in muscular structural lipids, as such changes have been associated with improved insulin sensitivity. Research Methods and Procedures: Skeletal muscle biopsies (vastus lateralis) were obtained from 13 obese....... Discussion: Desaturation of both muscle cell membrane phospholipid and IMTG was significant but modest during a VLCD in obese subjects. Further research must delineate whether such changes in skeletal muscle structural and depot lipid composition themselves are enough to promote the observed improvements...

  9. Contribution to the study of the electrodeposition of iron-nickel alloys; Contribution a l'etude du depot electrolytique des alliages fer-nickel

    Energy Technology Data Exchange (ETDEWEB)

    Valignat, J [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1967-12-01

    Using a coulometric technique based upon the anodic intentiostatic dissolution, we studied the potentiostatic, deposition of nickel, iron and nickel iron alloys. We have shown that the minimum of the curve I = f (t) (deposition current versus time) is probably due to the transitory blocking of the surface by hydrogen and that the syn-crystallisation of nickel and iron is responsible for the anomalous co-deposition of these two elements. (author) [French] En employant une methode coulometrique par dissolution anodique intensipstatique, nous avons etudie le depot potentiostatique du nickel, du fer et des alliages fer-nickel. Nous avons pu montrer que le minimum de la courbe I = f (t) enregistree au cours du depot est du probablement au blocage momentane de la surface par l'hydrogene et que la syncristallisation du fer et du nickel est responsable de l'anomalie du depot simultane de ces deux elements. (auteur)

  10. Vanadate impedes adipogenesis in mesenchymal stem cells derived from different depots within bone.

    Directory of Open Access Journals (Sweden)

    Frans Alexander Jacobs

    2016-08-01

    Full Text Available Glucocorticoid induced osteoporosis (GIO is associated with an increase in bone marrow adiposity which skews the differentiation of mesenchymal stem cell (MSC progenitors away from osteoblastogenesis and towards adipogenesis. We have previously found that vanadate, a non-specific protein tyrosine phosphatase inhibitor, prevents GIO in rats, but it was unclear whether vanadate directly influenced adipogenesis in bone-derived MSCs. For the present study, we investigated the effect of vanadate on adipogenesis in primary rat MSCs derived from bone marrow (bmMSCs and from the proximal end of the femur (pfMSCs. By passage 3 after isolation, both cell populations expressed the MSC cell surface markers CD90 and CD106, but not the haematopoietic marker CD45. However, although variable, expression of the fibroblast marker CD26 was higher in pfMSCs than in bmMSCs. Differentiation studies using osteogenic and adipogenic induction media (OM and AM, respectively demonstrated that pfMSCs rapidly accumulated lipid droplets within 1 week of exposure to AM, while bmMSCs isolated from the same femur only formed lipid droplets after 3 weeks of AM treatment. Conversely, pfMSCs exposed to OM produced mineralized extracellular matrix (ECM after 3 weeks, compared to 1 week for OM-treated bmMSCs. Vanadate (10 µM added to AM resulted in a significant reduction in AM-induced intracellular lipid accumulation and expression of adipogenic gene markers (PPARγ2, aP2, adipsin in both pfMSCs and bmMSCs. Pharmacological concentrations of glucocorticoids (1 µM alone did not induce lipid accumulation in either bmMSCs or pfMSCs, but resulted in significant cell death in pfMSCs. Our findings demonstrate the existence of at least two fundamentally different MSC depots within the femur, and highlights the presence of MSCs capable of rapid adipogenesis within the proximal femur, an area prone to osteoporotic fractures. In addition, our results suggest that the increased bone marrow

  11. Study on the thermal ignition of gasoline-air mixture in underground oil depots based on experiment and numerical simulation

    Science.gov (United States)

    Ou, Yihong; Du, Yang; Jiang, Xingsheng; Wang, Dong; Liang, Jianjun

    2010-04-01

    The study on the special phenomenon, occurrence process and control mechanism of gasoline-air mixture thermal ignition in underground oil depots is of important academic and applied value for enriching scientific theories of explosion safety, developing protective technology against fire and decreasing the number of fire accidents. In this paper, the research on thermal ignition process of gasoline-air mixture in model underground oil depots tunnel has been carried out by using experiment and numerical simulation methods. The calculation result has been demonstrated by the experiment data. The five stages of thermal ignition course, which are slow oxidation stage, rapid oxidation stage, fire stage, flameout stage and quench stage, have been firstly defined and accurately descried. According to the magnitude order of concentration, the species have been divided into six categories, which lay the foundation for explosion-proof design based on the role of different species. The influence of space scale on thermal ignition in small-scale space has been found, and the mechanism for not easy to fire is that the wall reflection causes the reflux of fluids and changes the distribution of heat and mass, so that the progress of chemical reactions in the whole space are also changed. The novel mathematical model on the basis of unification chemical kinetics and thermodynamics established in this paper provides supplementary means for the analysis of process and mechanism of thermal ignition.

  12. The fatty acid profile of fat depots from Santa Inês sheep fed spineless cactus (Opuntia ficus-indica Mill.).

    Science.gov (United States)

    Costa, Roberto G; Almeida, Michelly DA; Cruz, George Rodrigo B; Beltrão Filho, Edvaldo M; Ribeiro, Neila L; Madruga, Marta S; Queiroga, Rita de Cássia Re

    2017-10-01

    Fat is the tissue that varies most in animals from both a quantitative and distribution perspective. It plays a fundamental biological role as energy storage during food scarcity. Renal, pelvic and internal fat are deposited first. These fats are used to identify fatty acid profiles that may be considered beneficial or unhealthy. The aim of this study is to evaluate the fatty acid profile of fat depots in Santa Inês sheep finished in confinement with spineless cactus in their diets. The treatments included increasing levels of spineless cactus (Opuntia fícus-indica Mill.): T1 = 0%, T2 = 30%, T3 = 50%, and T4 = 70%. The diets significantly affected the adipose depots. The orthogonal contrast between the diet with no cactus (control) and the other diets indicates that the quantity of saturated fatty acids decreased and that the levels of mono-unsaturated and polyunsaturated fatty acids increased in animals fed spineless cactus. The use of spineless cactus in the diets of Santa Inês sheep affects the lipid profile of their fat depots, reducing the quantity of saturated fatty acids and increasing the quantity of mono-unsaturated and polyunsaturated fatty acids. The fatty acid profile of the fat depots indicates that these fats can be used to formulate meat products and add economic and nutritional value to such products, which increases sheep farmers' incomes. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  13. Ethical acceptability of offering financial incentives for taking antipsychotic depot medication: Patients' and clinicians' perspectives after a 12-month randomized controlled trial

    NARCIS (Netherlands)

    E.L. Noordraven (Ernst); M.H.N. Schermer (Maartje); P. Blanken (Peter); C.L. Mulder (Niels); A.I. Wierdsma (André)

    2017-01-01

    textabstractBackground: A randomized controlled trial 'Money for Medication'(M4M) was conducted in which patients were offered financial incentives for taking antipsychotic depot medication. This study assessed the attitudes and ethical considerations of patients and clinicians who participated in

  14. WATER TEMPERATURE and Other Data from MULTIPLE SHIPS From World-Wide Distribution from 19610101 to 19901212 (NODC Accession 9400138)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Sixty-two (62) data files and one doc file from Dr. Alan Longhurst, Bedford Institute of Oceanography, Dartmouth, Nova Scotia, Canada. These contain chlorophyll data...

  15. Fall Bottom Trawl Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The standardized NEFSC Fall Bottom Trawl Survey was initiated in 1963 and covered an area from Hudson Canyon, NY to Nova Scotia, Canada. Throughout the years,...

  16. Oceanography Branch Plankton Database

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Shelf-wide Research Vessel Surveys are conducted 4-8 times per year over the continental shelf from Cape Hatteras, North Carolina to Cape Sable, Nova Scotia, using...

  17. La Gran financiarización

    Directory of Open Access Journals (Sweden)

    Julio Castellanos Elías

    2015-05-01

    Full Text Available Reseña al libro de Polanyi Levitt, Kari "From The Great Transformation to the Great Financialization. On Karl Polanyi and Other Essays”, Fernwood Publishing, Nova Scotia, Canada, 2013, 286 pp.

  18. Long-Term Social Outcomes in Childhood Epilepsy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2007-12-01

    Full Text Available Population-based longitudinal and cross-sectional studies of social outcomes of children with epilepsy in different countries are reviewed by researchers at Dalhousie University, Halifax, Nova Scotia, Canada.Epilepsy, Chronic Disease, Idiopathic Epilepsy.

  19. Spring Bottom Trawl Survey

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The standardized NEFSC Spring Bottom Trawl Survey was initiated in 1968 and covered an area from Cape Hatteras, NC, to Nova Scotia, Canada, at depths >27m....

  20. North Atlantic Right Whale Sighting Advisory System (NARWSS)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Since 1995, PSB has been conducting line-transect aerial abundance surveys over waters ranging from North Carolina to the Gulf of St. Lawrence in Nova Scotia,...

  1. Leptin deficiency-induced obesity affects the density of mast cells in abdominal fat depots and lymph nodes in mice

    Directory of Open Access Journals (Sweden)

    Altintas Mehmet M

    2012-02-01

    Full Text Available Abstract Background Mast cells are implicated in the pathogenesis of obesity and insulin resistance. Here, we explored the effects of leptin deficiency-induced obesity on the density of mast cells in metabolic (abdominal fat depots, skeletal muscle, and liver and lymphatic (abdominal lymph nodes, spleen, and thymus organs. Fourteen-week-old male leptin-deficient ob/ob mice and their controls fed a standard chow were studied. Tissue sections were stained with toluidine blue to determine the density of mast cells. CD117/c-kit protein expression analysis was also carried out. Furthermore, mast cells containing immunoreactive tumor necrosis factor-α (TNF-α, a proinflammatory cytokine involved in obesity-linked insulin resistance, were identified by immunostaining. Results ob/ob mice demonstrated adiposity and insulin resistance. In abdominal fat depots, mast cells were distributed differentially. While most prevalent in subcutaneous fat in controls, mast cells were most abundant in epididymal fat in ob/ob mice. Leptin deficiency-induced obesity was accompanied by a 20-fold increase in the density of mast cells in epididymal fat, but a 13-fold decrease in subcutaneous fat. This finding was confirmed by CD117/c-kit protein expression analysis. Furthermore, we found that a subset of mast cells in epididymal and subcutaneous fat were immunoreactive for TNF-α. The proportion of mast cells immunoreactive for TNF-α was higher in epididymal than in subcutaneous fat in both ob/ob and control mice. Mast cells were also distributed differentially in retroperitoneal, mesenteric, and inguinal lymph nodes. In both ob/ob mice and lean controls, mast cells were more prevalent in retroperitoneal than in mesenteric and inguinal lymph nodes. Leptin deficiency-induced obesity was accompanied by increased mast cell density in all lymph node stations examined. No significant difference in the density of mast cells in skeletal muscle, liver, spleen, and thymus was

  2. Use of depot medroxyprogesterone acetate and prevalent leiomyoma in young African American women.

    Science.gov (United States)

    Harmon, Q E; Baird, D D

    2015-06-01

    Is use of depot medroxyprogesterone acetate (DMPA) a risk factor for or a protective factor against prevalent uterine leiomyoma? Ever use of DMPA was associated with a decreased risk (adjusted risk ratio (RR): 0.8, 95% confidence interval (CI): 0.6, 0.9) of prevalent leiomyoma in young African American women. Although progesterone is associated with growth of leiomyoma, previous epidemiological studies have shown a protective association for DMPA use. These previous studies may have been biased by studying clinically diagnosed leiomyoma (DMPA may mask symptoms thus delaying diagnoses). Cross sectional analysis of baseline data from a cohort study of 1696 African American women. Community-based recruitment (e.g. letters, flyers, radio and TV announcements) were used to enroll African American women between 23 and 34 years old without a previous diagnosis of leiomyoma in the Metropolitan Detroit area. Extensive questionnaire data were used to determine DMPA use and screening ultrasound detected the presence of leiomyoma ≥0.5 cm in diameter. Relative risks with adjustment for covariates were calculated for the presence of leiomyoma based on ever use of DMPA as well as duration and recency of use. Among the 1696 volunteers who enrolled, 43% had used DMPA. Leiomyoma were detected in 17% of those who had ever used DMPA compared with 26% of those who had never used DMPA. The reduction in prevalence remained after adjustment for potential confounders and was highest among women who had used DMPA for more than 4 years (adjusted RR: 0.5, 95% CI: 0.3, 0.8). The reduction in risk was seen for women whose most recent use was up to 8 years prior to study enrollment. The use of cross-sectional data means that the timing of initial fibroid development is not known, so the temporality of the association is uncertain. However in this sample of young women, most fibroids were small, suggesting that DMPA exposure may have occurred before leiomyoma development. Our findings are in

  3. An integrative transcriptomic approach to identify depot differences in genes and microRNAs in adipose tissues from high fat fed mice.

    Science.gov (United States)

    Wijayatunga, Nadeeja N; Pahlavani, Mandana; Kalupahana, Nishan S; Kottapalli, Kameswara Rao; Gunaratne, Preethi H; Coarfa, Cristian; Ramalingam, Latha; Moustaid-Moussa, Naima

    2018-02-06

    Obesity contributes to metabolic disorders such as diabetes and cardiovascular disease. Characterization of differences between the main adipose tissue depots, white (WAT) [including subcutaneous (SAT) and visceral adipose tissue (VAT)] and brown adipose tissue (BAT) helps to identify their roles in obesity. Thus, we studied depot-specific differences in whole transcriptome and miRNA profiles of SAT, VAT and BAT from high fat diet (HFD/45% of calories from fat) fed mice using RNA sequencing and small RNA-Seq. Using quantitative real-time polymerase chain reaction, we validated depot-specific differences in endoplasmic reticulum (ER) stress related genes and miRNAs using mice fed a HFD vs. low fat diet (LFD/10% of calories from fat). According to the transcriptomic analysis, lipogenesis, adipogenesis, inflammation, endoplasmic reticulum (ER) stress and unfolded protein response (UPR) were higher in VAT compared to BAT, whereas energy expenditure, fatty acid oxidation and oxidative phosphorylation were higher in BAT than in VAT of the HFD fed mice. In contrast to BAT, ER stress marker genes were significantly upregulated in VAT of HFD fed mice than the LFD fed mice. For the first time, we report depot specific differences in ER stress related miRNAs including; downregulation of miR-125b-5p, upregulation miR-143-3p, and miR-222-3p in VAT following HFD and upregulation of miR-30c-2-3p only in BAT following a HFD in mice than the LFD mice. In conclusion, HFD differentially regulates miRNAs and genes in different adipose depots with significant induction of genes related to lipogenesis, adipogenesis, inflammation, ER stress, and UPR in WAT compared to BAT.

  4. A team approach to improving colorectal cancer services using administrative health data

    OpenAIRE

    Porter Geoffrey; Urquhart Robin; Bu Jingyu; Kendell Cynthia; MacIntyre Maureen; Dewar Ron; Kephart George; Asada Yukiko; Grunfeld Eva

    2012-01-01

    Abstract Background Colorectal cancer (CRC) is the third most commonly diagnosed cancer in Canada and accounts for 11.9% of all cancer-related mortality. Fortunately, previous studies have provided evidence of improved outcomes from access to timely and appropriate health services along the disease trajectory in CRC. As a result, the CIHR/CCNS Team in Access to Colorectal Cancer Services in Nova Scotia (Team ACCESS) was created to build colorectal cancer (CRC) research capacity in Nova Scotia...

  5. EFFICIENCY OF REPEATED AND UNSCHEDULED TRAINING AS THE MEASURES TO PREVENT ACCIDENTS AT SUPPLY DEPOTS AND WAREHOUSES

    Directory of Open Access Journals (Sweden)

    Bocharova Irina Nikolaevna

    2013-05-01

    Full Text Available This paper presents the results of the analysis of the state of occupational safety at supply depots and warehouses. It is revealed that most accidents involve the employees who have less than one year’s service. Experience has proven that the preventive activities to avoid occupational traumatism are efficient when a complex of workplace safety measures is implemented. The experts consider the repeated and unscheduled training to be very important events. This is supported by the fact that among the employees of the commercial establishments who underwent repeated and unscheduled training, the number of individuals who suffered an accident is small. The efficient functioning of the occupational safety training system is infeasible without ensuring the motivation for assimilating the knowledge and forming the complete foundation for safe labor. In order to reduce the number of accidents, one should proceed from the principle of responding to accidents to the system for professional risk management.

  6. Depot-specific differences in angiogenic capacity of adipose tissue in differential susceptibility to diet-induced obesity

    Directory of Open Access Journals (Sweden)

    Mun-Gyu Song

    2016-11-01

    Full Text Available Objective: Adipose tissue (AT expansion requires AT remodeling, which depends on AT angiogenesis. Modulation of AT angiogenesis could have therapeutic promise for the treatment of obesity. However, it is unclear how the capacity of angiogenesis in each adipose depot is affected by over-nutrition. Therefore, we investigated the angiogenic capacity (AC of subcutaneous and visceral fats in lean and obese mice. Methods: We compared the AC of epididymal fat (EF and inguinal fat (IF using an angiogenesis assay in diet-induced obese (DIO mice and diet-resistant (DR mice fed a high-fat diet (HFD. Furthermore, we compared the expression levels of genes related to angiogenesis, macrophage recruitment, and inflammation using RT-qPCR in the EF and IF of lean mice fed a low-fat diet (LFD, DIO mice, and DR mice fed a HFD. Results: DIO mice showed a significant increase in the AC of EF only at 22 weeks of age compared to DR mice. The expression levels of genes related to angiogenesis, macrophage recruitment, and inflammation were significantly higher in the EF of DIO mice than in those of LFD mice and DR mice, while expression levels of genes related to macrophages and their recruitment were higher in the IF of DIO mice than in those of LFD and DR mice. Expression of genes related to angiogenesis (including Hif1a, Vegfa, Fgf1, Kdr, and Pecam1, macrophage recruitment, and inflammation (including Emr1, Ccr2, Itgax, Ccl2, Tnf, and Il1b correlated more strongly with body weight in the EF of HFD-fed obese mice compared to that of IF. Conclusions: These results suggest depot-specific differences in AT angiogenesis and a potential role in the susceptibility to diet-induced obesity. Keywords: Angiogenesis, Inflammation, Adipose tissue, Diet-induced obese mice, Diet-resistant mice, High-fat diet

  7. Disposal of chemical agents and munitions stored at Umatilla Depot Activity, Hermiston, Oregon. Final Phase 1 environmental report

    Energy Technology Data Exchange (ETDEWEB)

    Zimmerman, G.P.; Hillsman, E.L.; Johnson, R.O.; Miller, R.L.; Patton, T.G.; Schoepfle, G.M.; Tolbert, V.R.; Feldman, D.L.; Hunsaker, D.B. Jr.; Kroodsma, R.L.; Morrissey, J.; Rickert, L.W.; Staub, W.P.; West, D.C.

    1993-02-01

    The Umatilla Depot Activity (UMDA) near Hermiston, Oregon, is one of eight US Army installations in the continental United States where lethal unitary chemical agents and munitions are stored, and where destruction of agents and munitions is proposed under the Chemical Stockpile Disposal Program (CSDP). The chemical agent inventory at UMDA consists of 11.6%, by weight, of the total US stockpile. The destruction of the stockpile is necessary to eliminate the risk to the public from continued storage and to dispose of obsolete and leaking munitions. In 1988 the US Army issued a Final Programmatic Environmental Impact Statement (FPEIS) for the CSDP that identified on-site disposal of agents and munitions as the environmentally preferred alternative (i.e., the alternative with the least potential to cause significant adverse impacts), using a method based on five measures of risk for potential human health and ecosystem/environmental effects; the effectiveness and adequacy of emergency preparedness capabilities also played a key role in the FPEIS selection methodology. In some instances, the FPEIS included generic data and assumptions that were developed to allow a consistent comparison of potential impacts among programmatic alternatives and did not include detailed conditions at each of the eight installations. The purpose of this Phase 1 report is to examine the proposed implementation of on-site disposal at UMDA in light of more recent and more detailed data than those included in the FPEIS. Specifically, this Phase 1 report is intended to either confirm or reject the validity of on-site disposal for the UMDA stockpile. Using the same computation methods as in the FPEIS, new population data were used to compute potential fatalities from hypothetical disposal accidents. Results indicate that onsite disposal is clearly preferable to either continued storage at UMDA or transportation of the UMDA stockpile to another depot for disposal.

  8. Regional Differences of Proteins Expressing in Adipose Depots Isolated from Cows, Steers and Bulls as Identified by a Proteomic Approach

    Directory of Open Access Journals (Sweden)

    Jin Hyoung Cho

    2016-08-01

    Full Text Available Adipose tissue in the loin muscle area of beef cattle as a marbling factor is directly associated with beef quality. To elucidate whether properties of proteins involved in depot specific adipose tissue were sex-dependent, we analyzed protein expression of intramuscular adipose tissue (IMAT and omental adipose tissue (OMAT from Hanwoo cows, steers, and bulls of Korean native beef cattle by liquid chromatography-tandem mass spectrometry (LC-MS/MS–based proteomic analysis, quantitative polymerase chain reaction (PCR and western blot analysis. Two different adipose depots (i.e. intramuscular and omental were collected from cows (n = 7, steers (n = 7, or bulls (n = 7. LC-MS/MS revealed a total of 55 and 35 proteins in IMAT and OMAT, respectively. Of the 55 proteins identified, 44, 40, and 42 proteins were confirmed to be differentially expressed in IMAT of cows, steers, and bulls, respectively. In OMAT of cows, steers, and bulls, 33, 33, and 22 were confirmed to be differentially expressed, respectively. Tropomyosin (TPM 1, TPM 2, and TPM3 were subjected to verification by quantitative PCR and western blot analysis in IMAT and OMAT of Hanwoo cows, steers, and bulls as key factors closely associated with muscle development. Both mRNA levels and protein levels of TPM1, TPM2, and TPM3 in IMAT were lower in bulls compared to in cows or steers suggesting that they were positively correlated with marbling score and quality grade. Our results may aid the regulation of marbling development and improvement of meat quality grades in beef cattle.

  9. Chemical Stockpile Disposal Program: Review and comment on the Phase 1 environmental report for the Pueblo Depot Activity, Pueblo, Colorado

    International Nuclear Information System (INIS)

    Olshansky, S.J.; Krummel, J.R.; Policastro, A.J.; McGinnis, L.D.

    1994-03-01

    As part of the Chemical Stockpile Disposal Program, an independent review is presented of the US Army Phase I environmental report for the disposal of chemical agents and munitions stored at the Pueblo Depot Activity (PUDA) in Pueblo, Colorado. The Phase I report addresses new and additional concerns not incorporated in the final programmatic environmental impact statement (FPEIS). These concerns are addressed by examining site-specific data for the PUDA. On the basis of our review of the Phase I report, we concluded that on-site meteorological data from December 1988 to June 1992 appear to be of insufficient quality to have been used instead of the off-site Pueblo airport data. No additional meteorological data have been collected since June 1992. The Phase I report briefly mentions problems with the air pollution control system. These problems will likely require the systems to be upgraded at the Johnston Atoll site and at each of the other depots in the continental United States. Without such improvements, the probability of accidents during start-up and shutdown would likely increase. The Army has a lessons-learned program to incorporate improvements into the design of future facilities. The Phase I report does not make any design change commitments. These issues need to be fully evaluated and resolved before any final conclusion concerning the adequacy of the decision in the FPEIS can be made with respect to the PUDA. With the exception of this issue, the inclusion of other more detailed site-specific data in the Phase I report does not change the decision reached in the FPEIS (which favored on-site disposal at the PUDA). We recommend that site-specific data on water, ecological, socioeconomic, and cultural resources and emergency planning and preparedness be considered explicitly in the site-specific EIS decision-making process

  10. The watershed-scale optimized and rearranged landscape design (WORLD) model and local biomass processing depots for sustainable biofuel production: Integrated life cycle assessments

    Energy Technology Data Exchange (ETDEWEB)

    Eranki, Pragnya L.; Manowitz, David H.; Bals, Bryan D.; Izaurralde, Roberto C.; Kim, Seungdo; Dale, Bruce E.

    2013-07-23

    An array of feedstock is being evaluated as potential raw material for cellulosic biofuel production. Thorough assessments are required in regional landscape settings before these feedstocks can be cultivated and sustainable management practices can be implemented. On the processing side, a potential solution to the logistical challenges of large biorefi neries is provided by a network of distributed processing facilities called local biomass processing depots. A large-scale cellulosic ethanol industry is likely to emerge soon in the United States. We have the opportunity to influence the sustainability of this emerging industry. The watershed-scale optimized and rearranged landscape design (WORLD) model estimates land allocations for different cellulosic feedstocks at biorefinery scale without displacing current animal nutrition requirements. This model also incorporates a network of the aforementioned depots. An integrated life cycle assessment is then conducted over the unified system of optimized feedstock production, processing, and associated transport operations to evaluate net energy yields (NEYs) and environmental impacts.

  11. Monitoring and documentation of side effects from depot antipsychotic medication: an interdisciplinary audit of practice in a regional mental health service.

    LENUS (Irish Health Repository)

    Cleary, A

    2012-01-01

    The aim of this audit was to review current practice within a rural mental health service area on the monitoring and documentation of side effects of antipsychotic depot medication. Following a review of the literature on best practice internationally, an evidence based audit tool was adapted. A sample of 60 case files, care plans and prescriptions were audited between January and May 2010. This represented 31% of the total number of service users receiving depot injections in the mental health service region (n=181). The audit results revealed that most service users had an annual documented medical review and a documented prescription. However, only 5 (8%) case notes examined had documentation recorded describing the condition of the injection site and alternation of the injection site was recorded in only 28 (47%) case notes. No case notes examined had written consent to commence treatment recorded, and only 3 (5%) of case notes had documented that information on the depot injection and side effects was given. In 57 (95%) of case notes no documentation of recorded information on the depot and on side effects was given. Documentation of physical observations and tests revealed that 58% of cases had full blood count, liver function tests, thyroid function tests and fasting lipids recorded. All other tests (i.e. temperature, pulse, respirations, blood pressure, ECG) were recorded in less than 50% of cases. Prolactin levels were not recorded in any case. The lack of written consent was partly attributed to lack of recording of consent. The failure to monitor and record some\\r\

  12. Documentation and Analysis of the ’Miscellaneous’ Account Category within the DoD Instruction 7220.29-H Depot Level Maintenance Cost Accounting System.

    Science.gov (United States)

    1984-12-01

    34MISCELLANEOUS" ACCOUNT CATEGORY WITHIN THE DOD INSTRUCTION 7220.29-H DEPOT LEVEL MAINTENANCE COST ACCOUNTING SYSTEM by a. Steven Eugene Lehr CDecember 1984...PERFORMING ONG. REPORT NUMBER Maintenance Cost Accounting System 7. AUTHOR(&) S. CONTRACT OR GRANT NUMBER(@) Steven Eugene Lehr 9. PERFORMING ORGANIZATION...Availability Codes IS. KEY WORDS (Continue on reverse *ids It necessary and Identify by block number) Dvi Special Uniform Cost Accounting System DoD

  13. The effect of dietary copper supplementation on fatty acid profile and oxidative stability of adipose depots in Boer x Spanish goats.

    Science.gov (United States)

    Cummins, K A; Solaiman, S G; Bergen, W G

    2008-02-01

    A feeding trial was designed to examine the effects of copper sulfate pentahydrate (CuSO(4).5H(2)O) on the fatty acid composition and oxidative stability in muscle and adipose tissues of Boer x Spanish goat kids. Fifteen (n = 5 per treatment) goats were fed 0, 100, or 200 mg of supplemental Cu per day as copper sulfate for 98 d. The animals were slaughtered, and LM, s.c. adipose from the sternal region, and mesenteric adipose tissues were collected. Total lipids were extracted with chloroform:methanol (2:1), methylated and isolated via GLC from all tissues. The subsequent peaks were then positively identified by mass spectrometry. Thiobarbituric acid-reactive substances were measured also. In s.c. adipose, dietary Cu significantly decreased C14:0 (P = 0.03) and C16:0 (P = 0.01). In muscle, C15:0 (P = 0.03) was linearly increased by Cu. Dietary Cu supplementation did not influence oxidative stability in goat muscle or s.c. adipose. Copper supplementation at 200 mg/d resulted in a significant increase in malondialdehyde in mesenteric adipose (P = 0.01) compared with the 0 or 100 mg/d groups. These results indicate that lipid composition may differ from depot to depot and that depending on the depot, dietary Cu seems to elicit a variable response on the fatty acid composition.

  14. Effect of Buprenorphine Weekly Depot (CAM2038) and Hydromorphone Blockade in Individuals With Opioid Use Disorder: A Randomized Clinical Trial.

    Science.gov (United States)

    Walsh, Sharon L; Comer, Sandra D; Lofwall, Michelle R; Vince, Bradley; Levy-Cooperman, Naama; Kelsh, Debra; Coe, Marion A; Jones, Jermaine D; Nuzzo, Paul A; Tiberg, Fredrik; Sheldon, Behshad; Kim, Sonnie

    2017-09-01

    Buprenorphine is an efficacious, widely used treatment for opioid use disorder (OUD). Daily oral transmucosal formulations can be associated with misuse, diversion, and nonadherence; these limitations may be obviated by a sustained release formulation. To evaluate the ability of a novel, weekly, subcutaneous buprenorphine depot formulation, CAM2038, to block euphorigenic opioid effects and suppress opioid withdrawal in non-treatment-seeking individuals with OUD. This multisite, double-blind, randomized within-patient study was conducted at 3 controlled inpatient research facilities. It involved 47 adults with DSM-V moderate-to-severe OUD. The study was conducted from October 12, 2015 (first patient enrolled), to April 21, 2016 (last patient visit). A total of five 3-day test sessions evaluated the response to hydromorphone (0, 6, and 18 mg intramuscular in random order; 1 dose/session/day). After the first 3-day session (ie, qualification phase), participants were randomized to either CAM2038 weekly at 24 mg (n = 22) or 32 mg (n = 25); the assigned CAM2038 dose was given twice, 1 week apart (day 0 and 7). Four sets of sessions were conducted after randomization (days 1-3, 4-6, 8-10, and 11-13). The primary end point was maximum rating on the visual analog scale for drug liking. Secondary end points included other visual analog scale (eg, high and desire to use), opioid withdrawal scales, and physiological and pharmacokinetic outcomes. A total of 46 of 47 randomized participants (mean [SD] age, 35.5 [9] years; 76% male [n = 35]) completed the study. Both weekly CAM2038 doses produced immediate and sustained blockade of hydromorphone effects (liking maximum effect, CAM2038, 24 mg: effect size, 0.813; P withdrawal (Clinical Opiate Withdrawal Scale, CAM2038, 24 mg: effect size, 0.617; P opioid blockade and withdrawal suppression. The results support the use of this depot formulation for treatment initiation and stabilization of patients with OUD, with

  15. Long-term effect of depot medroxyprogesterone acetate on vaginal microbiota, epithelial thickness and HIV target cells.

    Science.gov (United States)

    Mitchell, Caroline M; McLemore, Leslie; Westerberg, Katharine; Astronomo, Rena; Smythe, Kimberly; Gardella, Carolyn; Mack, Matthias; Magaret, Amalia; Patton, Dorothy; Agnew, Kathy; McElrath, M Juliana; Hladik, Florian; Eschenbach, David

    2014-08-15

    Depot medroxyprogesterone acetate (DMPA) has been linked to human immunodeficiency virus type 1 (HIV-1) acquisition. Vaginal microbiota of women using DMPA for up to 2 years were cultured. Mucosal immune cell populations were measured by immunohistological staining. Over 12 months, the proportion with H2O2-positive lactobacilli decreased (n = 32; 53% vs 27%; P = .03). Median vaginal CD3(+) cells also decreased (n = 15; 355 vs 237 cells/mm(2); P = .03), as did CD3(+)CCR5(+) cells (195 vs 128 cells/mm(2); P = .04), HLA-DR(+) cells (130 vs 96 cells/mm(2); P = .27), and HLA-DR(+)CCR5(+) cells (18 vs 10 cells/mm(2); P = .33). DMPA contraception does not increase vaginal mucosal CCR5(+) HIV target cells but does decrease CD3(+) T lymphocytes and vaginal H2O2-producing lactobacilli. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  16. Oil fuel delivery optimization for multi product and multi depot: the case of petrol station replenishment problem (PSRP)

    Science.gov (United States)

    Surjandari, Isti; Rachman, Amar; Dianawati, Fauzia; Wibowo, R. Pramono

    2011-10-01

    With the Oil and Gas Law No. 22 of 2001, national and foreign private enterprises can invest in all sectors of Oil and Gas in Indonesia. In anticipation of this free competition, Pertamina, as a state-owned enterprises, which previously had monopolized the oil and gas business activities in Indonesia, should be able to improve services as well as the efficiency in order to compete in the free market, especially in terms of cost efficiency of fuel distribution to gas station (SPBU). To optimize the distribution activity, it is necessary to design a scheduling system and its fuel delivery routes daily to every SPBU. The determination of routes and scheduling delivery of fuel to the SPBU can be modeled as a Petrol Station Replenishment Problem (PSRP) with the multi-depot, multi-product, time windows and split deliveries, which in this study will be completed by the Tabu Search algorithm (TS). This study was conducted in the area of Bandung, the capital of West Java province, which is a big city and the neighboring city of Jakarta, the capital city of Indonesia. By using the fuel delivery data for one day, the results showed a decrease of 16.38% of the distance of the route compared to the current conditions, which impacted on the reduction of distribution costs and decrease the number of total trips by 5.22% and 3.83%.

  17. Differential patterns of serum concentration and adipose tissue expression of chemerin in obesity: adipose depot specificity and gender dimorphism.

    Science.gov (United States)

    Alfadda, Assim A; Sallam, Reem M; Chishti, Muhammad Azhar; Moustafa, Amr S; Fatma, Sumbul; Alomaim, Waleed S; Al-Naami, Mohammed Y; Bassas, Abdulelah F; Chrousos, George P; Jo, Hyunsun

    2012-06-01

    Chemerin, a recognized chemoattractant, is expressed in adipose tissue and plays a role in adipocytes differentiation and metabolism. Gender- and adipose tissue-specific differences in human chemerin expression have not been well characterized. Therefore, these differences were assessed in the present study. The body mass index (BMI) and the circulating levels of chemerin and other inflammatory, adiposity and insulin resistance markers were assessed in female and male adults of varying degree of obesity. Chemerin mRNA expression was also measured in paired subcutaneous and visceral adipose tissue samples obtained from a subset of the study subjects. Serum chemerin concentrations correlated positively with BMI and serum leptin levels and negatively with high density lipoprotein (HDL)-cholesterol levels. No correlation was found between serum chemerin concentrations and fasting glucose, total cholesterol, low density lipoprotein (LDL)-cholesterol, triglycerides, insulin, C-reactive protein or adiponectin. Similarly, no relation was observed with the homeostasis model assessment for insulin resistance (HOMA-IR) values. Gender- and adipose tissue-specific differences were observed in chemerin mRNA expression levels, with expression significantly higher in women than men and in subcutaneous than visceral adipose tissue. Interestingly, we found a significant negative correlation between circulating chemerin levels and chemerin mRNA expression in subcutaneous fat. Among the subjects studied, circulating chemerin levels were associated with obesity markers but not with markers of insulin resistance. At the tissue level, fat depot-specific differential regulation of chemerin mRNA expression might contribute to the distinctive roles of subcutaneous vs. visceral adipose tissue in human obesity.

  18. Changes in Vaginal Microbiota and Immune Mediators in HIV-1-Seronegative Kenyan Women Initiating Depot Medroxyprogesterone Acetate.

    Science.gov (United States)

    Roxby, Alison C; Fredricks, David N; Odem-Davis, Katherine; Ásbjörnsdóttir, Kristjana; Masese, Linnet; Fiedler, Tina L; De Rosa, Stephen; Jaoko, Walter; Kiarie, James N; Overbaugh, Julie; McClelland, R Scott

    2016-04-01

    Depot medroxyprogesterone acetate (DMPA) is associated with HIV acquisition. We studied changes in vaginal microbiota and inflammatory milieu after DMPA initiation. In a cohort of HIV-negative Kenyan women, we collected monthly vaginal swabs over 1 year before and after DMPA. Using quantitative polymerase chain reaction, we compared quantities of Lactobacillus crispatus, Lactobacillus jensenii, Lactobacillus iners, Gardnerella vaginalis, and total bacterial load (16S ribosomal RNA gene levels). Six vaginal immune mediators were measured with enzyme-linked immunosorbent assay. Trends in the detection and quantity of bacteria were estimated by logistic and linear mixed-effects regression. From 2010 to 2012, 15 HIV-seronegative women initiated DMPA, contributing 85 visits (median, 6 visits/woman; range, 3-8 visits/woman). The median time of DMPA-exposed follow-up was 8.4 months (range, 1.5-11.6 months). Seven women (46%) had bacterial vaginosis within 70 days before DMPA start. L. iners was detected in 13 women (87%) before DMPA start, but other lactobacilli were rarely detected. Gardnerella vaginalis decreased by 0.21 log10 copies per swab per month after DMPA exposure (P = 0.01). Total bacterial load decreased by 0.08 log10 copies per swab per month of DMPA (P = 0.02). Sustained decreases in interleukin (IL)-6 (P = 0.03), IL-8 (P = 0.04), and IL-1 receptor antagonist (P vaginal bacterial concentrations and levels of inflammatory mediators. Further studies are warranted to outline components of the vaginal microbiota influenced by DMPA use and impact on HIV susceptibility.

  19. Retrospective investigation of testosterone undecanoate depot for the long-term treatment of male hypogonadism in clinical practice.

    Science.gov (United States)

    Conaglen, Helen M; Paul, Ryan G; Yarndley, Tania; Kamp, Jozef; Elston, Marianne S; Conaglen, John V

    2014-02-01

    Testosterone undecanoate depot (TUD) administered intramuscularly is an effective form of testosterone replacement therapy (TRT) for male hypogonadism. Because of the ease of administration, TUD therapy may be preferable to subcutaneously implanted extended release T pellet implants (TI). The primary objective was to retrospectively assess the efficacy and safety of long-term (≥ 2 years therapy) TUD therapy in the clinical setting. The secondary objective was to retrospectively compare TUD with TI therapy. Retrospective data were collected from the Waikato Hospital Endocrine Database for 179 hypogonadal men treated with TUD for ≥ 2 years from 1998-2011, with 124 of these men receiving previous TI therapy. The main outcome measure for efficacy was serum trough total testosterone (TT), and for safety an increase in hemoglobin (Hb) and/or hematocrit (Hct), rise in prostate-specific antigen (PSA) and/or prostatic biopsy and alteration in body mass index and lipid profile. Additional outcome measures were changes in the dosing and/or interval regimens for TUD therapy. Overall, 72% of trough TT levels were in the normal range for TUD therapy compared with 53% of trough TT levels during TI therapy. TUD therapy was well tolerated with 162 men (90.5%) completing 2 years of treatment, and only seven men (3.9%) stopping TUD because of adverse effects. A rise in Hb and/or Hct occurred in 25 men (14%), and a significant rise in PSA in 20 men (13%) at some stage during TUD therapy. At 2 years, 91% of men received the standard 1,000 mg TUD dose with 66% at the standard dosing interval of 10-14 weekly. TUD is an efficacious, safe, and well tolerated form of TRT, and individual optimisation of the dose and/or interval is only required in the minority of men. Particularly given the ease of administration, TUD was the preferred TRT for both patients and clinicians. © 2013 International Society for Sexual Medicine.

  20. Rats and rabbits as pharmacokinetic screening tools for long acting intramuscular depots: case study with paliperidone palmitate suspension.

    Science.gov (United States)

    Patel, Harilal; Patel, Prakash; Modi, Nirav; Patel, Pinakin; Wagh, Yogesh; George, Alex; Desai, Nirmal; Srinivas, Nuggehally R

    2018-05-08

    Development of prodrug of 9-hydroxyrisperidone (paliperidone) long-acting intramuscular injection has enabled delivery over four-week time period with improved compliance. The key aim of this work was to establish a reliable preclinical model which may potentially serve as a screening tool for judging the pharmacokinetics of paliperidone formulation(s) prior to human clinical work. Sparse sampling composite study was used in rats, (Wistar/Sprague-Dawley (SD; n = 10)) and a serial blood sampling study design was used in rabbits (n = 4). Animals received intramuscular injection of paliperidone palmitate in the thigh muscle at dose of 16 (rats) and 4.5 mg/kg (rabbits). Samples were drawn in rats (retro-orbital sinus) and rabbits (central ear artery) and were analysed for paliperidone using liquid chromatography-mass spectrometry/ mass spectrometry (LC-MS/MS) assay. The plasma data was subjected to pharmacokinetic analysis. Following intramuscular injection of depot formulation in Wistar/SD rats and rabbits, absorption of paliperidone was slow and gradual with median value of time to reach maximum concentration (T max ) occurring on day 7. The exposures (i.e. area under the curve (AUC; 0-28) days) were 18,597, 21,865 and 18,120 ng.h/mL, in Wistar, SD and rabbits, respectively. The clearance was slow and supported long half-life (8-10 days). Either one of the two models can serve as a research tool for establishing pharmacokinetics of paliperidone formulation(s).

  1. Characterization of the fate and transport of nitroaromatic compounds at a former DoD ordnance depot site

    Energy Technology Data Exchange (ETDEWEB)

    Klausmeier, M.E.; Yoon, J.

    1999-07-01

    The 975-acre Former Nansemond Ordnance Depot (FNOD) in Suffolk, Virginia was used by the Department of Defense (DoD) from 1917 until the mid-1950's for preparation, storage, transportation, inspection and demilitarization of many classes of ammunition and ordnance. Approximately 28 areas of Concern (AOC) have been identified by the EPA as areas that could pose potential risk to human health or the environment. The primary contaminants of concern are some trace metals and explosive compounds. During a summer 1987 field investigation, a slab of crystalline TNT was found which was estimated to weigh several tons. An enhanced MODFLOW model is being used to identify subsurface flow patterns. The calibrated model will be used to identify contaminant fate and transport behavior at the site. Enhancements to the MODFLOW model include an updated block-centered flow package (BCF4) and an updated recharge-seepage face boundary package (RSF4) to utilize for the FNOD site flow characterization. BCF4 package accurately delineates the water table without relying on an ad hoc rewetting procedure. This is accomplished by calculating the hydraulic head value required to transmit recharging water through the unsaturated zone without inactivating dry cells. The recharge-seepage face package eliminates the projection of heads above the ground surface by adjusting recharge to a cell when a user supplied ponding depth is reached. Using a regional model, a telescoping grid refinement technique was implemented to calculate the boundary conditions around the area of interest and to model quantity and quality interactions between surface and subsurface water regimes in a realistic manner.

  2. Android fat depot is more closely associated with metabolic syndrome than abdominal visceral fat in elderly people.

    Science.gov (United States)

    Kang, Seon Mee; Yoon, Ji Won; Ahn, Hwa Young; Kim, So Yeon; Lee, Kyoung Ho; Shin, Hayley; Choi, Sung Hee; Park, Kyong Soo; Jang, Hak Chul; Lim, Soo

    2011-01-01

    Fat accumulation in android compartments may confer increased metabolic risk. The incremental utility of measuring regional fat deposition in association with metabolic syndrome (MS) has not been well described particularly in an elderly population. As part of the Korean Longitudinal Study on Health and Aging, which is a community-based cohort study of people aged more than 65 years, subjects (287 male, 75.9±8.6 years and 278 female, 76.0±8.8 years) with regional body composition data using Dual energy X-ray absorptiometry for android/gynoid area, computed tomography for visceral/subcutaneous adipose tissue (VAT/SAT), and cardiometabolic markers including adiponectin and high-sensitivity CRP were enrolled. We investigated the relationship between regional body composition and MS in multivariate regression models. Mean VAT and SAT area was 131.4±65.5 cm(2) and 126.9±55.2 cm(2) in men (P = 0.045) and 120.0±46.7 cm(2) and 211.8±65.9 cm(2) in women (Pandroid and gynoid fat amount was 1.8±0.8 kg and 2.5±0.8 kg in men and 2.0±0.6 kg and 3.3±0.8 kg in women, respectively (both Pandroid fat amount was strongly correlated with most metabolic risk factors compared to SAT or gynoid fat. Furthermore, android fat amount was significantly associated with clustering of MS components after adjustment for multiple parameters including age, gender, adiponectin, hsCRP, a surrogate marker of insulin resistance, whole body fat mass and VAT area. Our findings are consistent with the hypothesized role of android fat as a pathogenic fat depot in the MS. Measurement of android fat may provide a more complete understanding of metabolic risk associated with variations in fat distribution.

  3. Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice

    Science.gov (United States)

    Chamorro-García, Raquel; Sahu, Margaret; Abbey, Rachelle J.; Laude, Jhyme; Pham, Nhieu

    2013-01-01

    Background: We have previously shown that exposure to tributyltin (TBT) modulates critical steps of adipogenesis through RXR/PPARγ and that prenatal TBT exposure predisposes multipotent mesenchymal stem cells (MSCs) to become adipocytes by epigenetic imprinting into the memory of the MSC compartment. Objective: We tested whether the effects of prenatal TBT exposure were heritable in F2 and F3 generations. Methods: We exposed C57BL/6J female mice (F0) to DMSO vehicle, the pharmaceutical obesogen rosiglitazone (ROSI), or TBT (5.42, 54.2, or 542 nM) throughout pregnancy via the drinking water. F1 offspring were bred to yield F2, and F2 mice were bred to produce F3. F1 animals were exposed in utero and F2 mice were potentially exposed as germ cells in the F1, but F3 animals were never exposed to the chemicals. We analyzed the effects of these exposures on fat depot weights, adipocyte number, adipocyte size, MSC programming, hepatic lipid accumulation, and hepatic gene expression in all three generations. Discussion: Prenatal TBT exposure increased most white adipose tissue (WAT) depot weights, adipocyte size, and adipocyte number, and reprogrammed MSCs toward the adipocyte lineage at the expense of bone in all three generations. Prenatal TBT exposure led to hepatic lipid accumulation and up-regulated hepatic expression of genes involved in lipid storage/transport, lipogenesis, and lipolysis in all three subsequent generations. Conclusions: Prenatal TBT exposure produced transgenerational effects on fat depots and induced a phenotype resembling nonalcoholic fatty liver disease through at least the F3 generation. These results show that early-life obesogen exposure can have lasting effects. PMID:23322813

  4. Ethical acceptability of offering financial incentives for taking antipsychotic depot medication: patients' and clinicians' perspectives after a 12-month randomized controlled trial.

    Science.gov (United States)

    Noordraven, Ernst L; Schermer, Maartje H N; Blanken, Peter; Mulder, Cornelis L; Wierdsma, André I

    2017-08-29

    A randomized controlled trial 'Money for Medication'(M4M) was conducted in which patients were offered financial incentives for taking antipsychotic depot medication. This study assessed the attitudes and ethical considerations of patients and clinicians who participated in this trial. Three mental healthcare institutions in secondary psychiatric care in the Netherlands participated in this study. Patients (n = 169), 18-65 years, diagnosed with schizophrenia, schizoaffective disorder or another psychotic disorder who had been prescribed antipsychotic depot medication, were randomly assigned to receive 12 months of either treatment as usual plus a financial reward for each depot of medication received (intervention group) or treatment as usual alone (control group). Structured questionnaires were administered after the 12-month intervention period. Data were available for 133 patients (69 control and 64 intervention) and for 97 clinicians. Patients (88%) and clinicians (81%) indicated that financial incentives were a good approach to improve medication adherence. Ethical concerns were categorized according to the four-principles approach (autonomy, beneficence, non-maleficence, and justice). Patients and clinicians alike mentioned various advantages of M4M in clinical practice, such as increased medication adherence and improved illness insight; but also disadvantages such as reduced intrinsic motivation, loss of autonomy and feelings of dependence. Overall, patients evaluated financial incentives as an effective method of improving medication adherence and were willing to accept this reward during clinical treatment. Clinicians were also positive about the use of this intervention in daily practice. Ethical concerns are discussed in terms of patient autonomy, beneficence, non-maleficence and justice. We conclude that this intervention is ethically acceptable under certain conditions, and that further research is necessary to clarify issues of benefit

  5. The Hereptofauna of Letterkenny Army Depot, South-Central Pennsylvania: A Starting Point to the Long-Term Monitoring and Management of Amphibians and Reptiles

    Science.gov (United States)

    2010-06-01

    Journal of Kansas Herpetology Number 34 (June 2010) 11 www.cnah.org/khs ARtIClES tHE HERpEtofAUNA of lEttERKENNY ARMY dEpot, SoUtH-CENtRAl...compare the herpetological commu- nity currently present at the site with that expected from prior literature (felbaum, 1995; Hulse et al., 2001; tetra...Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18 Journal of Kansas Herpetology Number 34 (June 2010) 12 www.cnah.org/khs agricultural and other

  6. Determination of lymph flow in murine oral mucosa using depot clearance of near-infrared-labeled albumin.

    Science.gov (United States)

    Papadakou, Panagiota; Karlsen, Tine Veronica; Wiig, Helge; Berggreen, Ellen

    2015-10-01

    The lymphatic vessels are playing an important role in inflammation since they return extravasated fluid, proteins, and cells back into the circulation and regulate immune cell trafficking. The oral mucosa, including gingiva, is well supplied with lymphatic vessels and is frequently challenged with inflammatory insults. Lymphatic vessels in gingiva protect against periodontal disease development, but quantification of lymph flow in this area has so far never been performed, due to lack of reliable methods. Mice of FVB strain (n=17) were anesthetized with isoflurane and placed on a jaw retraction board allowing the mouth to be kept open and stable. Albumin conjugated with Alexa680-fluorochrome (with or without LPS from Porphyromonas gingivalis) was injected superficially in oral mucosa mesio-buccal to the left first molar in each mouse. 60 min post-injection the mouse was transferred to an OptixMX3 optical imager where the total fluorescence was measured in the posterior facial area. The measurements continued further every 60 min for 7h for each mouse. The mice were awake and active between measurements. The in vivo washout of Alexa680-albumin was calculated using the natural logarithm of the relative values creating a negative slope for each mouse. Statistical analysis of variance was performed. The injection and distribution site for tracer was verified with India ink and shown to be in the interstitium below the oral mucosal epithelium, in an area well supplied with initial lymphatic vessels. Washout of the tracer Alexa680-albumin was log-linear, and the basal lymph flow calculated from depot clearance averaged -0.28 ± 0.08%/min (n=8). The clearance was significantly faster (-0.30 ± 0.08%/min, n=9) in acutely inflamed oral mucosa (p=0.0326). We developed a method that can successfully quantify the lymph flow in oral mucosa in steady state conditions and under acute perturbation. By use of this method, new information about the lymphatic function in oral mucosa

  7. Persistent organic pollutant levels in human visceral and subcutaneous adipose tissue in obese individuals—Depot differences and dysmetabolism implications

    Energy Technology Data Exchange (ETDEWEB)

    Pestana, Diogo, E-mail: diogopestana@gmail.com [Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Centro de Investigação Médica, P-4200-450 Porto (Portugal); CINTESIS—Center for Research in Health Technologies and Information Systems, P-4200-450 Porto (Portugal); Faria, Gil [General Surgery Department, S. João Hospital, Faculty of Medicine, University of Porto, P-4200-450 Porto (Portugal); Sá, Carla [Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Centro de Investigação Médica, P-4200-450 Porto (Portugal); Fernandes, Virgínia C. [Chemistry Investigation Centre (CIQ), Department of Chemistry, Faculty of Sciences, University of Porto, P-4169-007 Porto (Portugal); Requimte—Instituto Superior de Engenharia, Instituto Politécnico do Porto, P-4200-072 Porto (Portugal); Teixeira, Diana; Norberto, Sónia [Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Centro de Investigação Médica, P-4200-450 Porto (Portugal); Faria, Ana [Department of Biochemistry (U38-FCT), Faculty of Medicine, University of Porto, Centro de Investigação Médica, P-4200-450 Porto (Portugal); Chemistry Investigation Centre (CIQ), Department of Chemistry, Faculty of Sciences, University of Porto, P-4169-007 Porto (Portugal); Faculty of Nutrition and Food Sciences, University of Porto, P-4200-465 Porto (Portugal); and others

    2014-08-15

    Background: The role of persistent organic pollutants (POPs) with endocrine disrupting activity in the aetiology of obesity and other metabolic dysfunctions has been recently highlighted. Adipose tissue (AT) is a common site of POPs accumulation where they can induce adverse effects on human health. Objectives: To evaluate the presence of POPs in human visceral (vAT) and subcutaneous (scAT) adipose tissue in a sample of Portuguese obese patients that underwent bariatric surgery, and assess their putative association with metabolic disruption preoperatively, as well as with subsequent body mass index (BMI) reduction. Methods: AT samples (n=189) from obese patients (BMI ≥35) were collected and the levels of 13 POPs were determined by gas chromatography with electron-capture detection (GC-ECD). Anthropometric and biochemical data were collected at the time of surgery. BMI variation was evaluated after 12 months and adipocyte size was measured in AT samples. Results: Our data confirm that POPs are pervasive in this obese population (96.3% of detection on both tissues), their abundance increasing with age (R{sub S}=0.310, p<0.01) and duration of obesity (R{sub S}=0.170, p<0.05). We observed a difference in AT depot POPs storage capability, with higher levels of ΣPOPs in vAT (213.9±204.2 compared to 155.1±147.4 ng/g of fat, p<0.001), extremely relevant when evaluating their metabolic impact. Furthermore, there was a positive correlation between POP levels and the presence of metabolic syndrome components, namely dysglycaemia and hypertension, and more importantly with cardiovascular risk (R{sub S}=0.277, p<0.01), with relevance for vAT (R{sub S}=0.315, p<0.01). Finally, we observed an interesting relation of higher POP levels with lower weight loss in older patients. Conclusion: Our sample of obese subjects allowed us to highlight the importance of POPs stored in AT on the development of metabolic dysfunction in a context of obesity, shifting the focus to their

  8. Persistent organic pollutant levels in human visceral and subcutaneous adipose tissue in obese individuals—Depot differences and dysmetabolism implications

    International Nuclear Information System (INIS)

    Pestana, Diogo; Faria, Gil; Sá, Carla; Fernandes, Virgínia C.; Teixeira, Diana; Norberto, Sónia; Faria, Ana

    2014-01-01

    Background: The role of persistent organic pollutants (POPs) with endocrine disrupting activity in the aetiology of obesity and other metabolic dysfunctions has been recently highlighted. Adipose tissue (AT) is a common site of POPs accumulation where they can induce adverse effects on human health. Objectives: To evaluate the presence of POPs in human visceral (vAT) and subcutaneous (scAT) adipose tissue in a sample of Portuguese obese patients that underwent bariatric surgery, and assess their putative association with metabolic disruption preoperatively, as well as with subsequent body mass index (BMI) reduction. Methods: AT samples (n=189) from obese patients (BMI ≥35) were collected and the levels of 13 POPs were determined by gas chromatography with electron-capture detection (GC-ECD). Anthropometric and biochemical data were collected at the time of surgery. BMI variation was evaluated after 12 months and adipocyte size was measured in AT samples. Results: Our data confirm that POPs are pervasive in this obese population (96.3% of detection on both tissues), their abundance increasing with age (R S =0.310, p<0.01) and duration of obesity (R S =0.170, p<0.05). We observed a difference in AT depot POPs storage capability, with higher levels of ΣPOPs in vAT (213.9±204.2 compared to 155.1±147.4 ng/g of fat, p<0.001), extremely relevant when evaluating their metabolic impact. Furthermore, there was a positive correlation between POP levels and the presence of metabolic syndrome components, namely dysglycaemia and hypertension, and more importantly with cardiovascular risk (R S =0.277, p<0.01), with relevance for vAT (R S =0.315, p<0.01). Finally, we observed an interesting relation of higher POP levels with lower weight loss in older patients. Conclusion: Our sample of obese subjects allowed us to highlight the importance of POPs stored in AT on the development of metabolic dysfunction in a context of obesity, shifting the focus to their metabolic effects

  9. Body frame size in school children is related to the amount of adipose tissue in different depots but not to adipose distribution.

    Science.gov (United States)

    Guzmán-de la Garza, Francisco J; González Ayala, Alejandra E; Gómez Nava, Marisol; Martínez Monsiváis, Leislie I; Salinas Martínez, Ana M; Ramírez López, Erik; Mathiew Quirós, Alvaro; Garcia Quintanilla, Francisco

    2017-09-10

    The main aim of this study was to test the hypothesis that body frame size is related to the amount of fat in different adipose tissue depots and to fat distribution in schoolchildren. Children aged between 5 and 10 years were included in this cross-sectional study (n = 565). Body frame size, adiposity markers (anthropometric, skinfolds thickness, and ultrasound measures), and fat distribution indices were analyzed. Correlation coefficients adjusted by reliability were estimated and analyzed by sex; the significance of the difference between two correlation coefficients was assessed using the Fisher z-transformation. The sample included primarily urban children; 58.6% were normal weight, 16.1% overweight, 19.6% obese, and the rest were underweight. Markers of subcutaneous adiposity, fat mass and fat-free mass, and preperitoneal adiposity showed higher and significant correlations with the sum of the biacromial + bitrochanteric diameter than with the elbow diameter, regardless of sex. The fat distribution conicity index presented significant but weak correlations; and visceral adipose tissue, hepatic steatosis, and the waist-for-hip ratio were not significantly correlated with body frame size measures. Body frame size in school children was related to the amount of adipose tissue in different depots, but not adipose distribution. More studies are needed to confirm this relationship and its importance to predict changes in visceral fat deposition during growth. © 2017 Wiley Periodicals, Inc.

  10. NeuronDepot: Keeping your colleagues in sync by combining modern cloud storage services, the local file system, and simple web applications

    Directory of Open Access Journals (Sweden)

    Philipp L Rautenberg

    2014-06-01

    Full Text Available Neuroscience today deals with a data deluge derived from the availability of high-throughput sensors of brain structure and brain activity, and increased computational resources for detailed simulations with complex output. We report here (1 a novel approach to data sharing between collaborating scientists that brings together file system tools and cloud technologies, (2 a service implementing this approach, called NeuronDepot, and (3 an example application of the service to a complex use case in the neurosciences. The main drivers for our approach are to facilitate collaborations with a transparent, automated data flow that shields scientists from having to learn new tools or data structuring paradigms. Using NeuronDepot is simple: one-time data assignment from the originator and cloud based syncing – thus making experimental and modeling data available across the collaboration with minimum overhead. Since data sharing is cloud based, our approach opens up the possibility of using new software developments and hardware scalabitliy which are associated with elastic cloud computing. We provide an implementation that relies on existing synchronization services and is usable from all devices via a reactive web interface. We are motivating our solution by solving the practical problems of the GinJang project, a collaboration of three universities across eight time zones with a complex workflow encompassing data from electrophysiological recordings, imaging, morphological reconstructions, and simulations.

  11. NeuronDepot: keeping your colleagues in sync by combining modern cloud storage services, the local file system, and simple web applications.

    Science.gov (United States)

    Rautenberg, Philipp L; Kumaraswamy, Ajayrama; Tejero-Cantero, Alvaro; Doblander, Christoph; Norouzian, Mohammad R; Kai, Kazuki; Jacobsen, Hans-Arno; Ai, Hiroyuki; Wachtler, Thomas; Ikeno, Hidetoshi

    2014-01-01

    Neuroscience today deals with a "data deluge" derived from the availability of high-throughput sensors of brain structure and brain activity, and increased computational resources for detailed simulations with complex output. We report here (1) a novel approach to data sharing between collaborating scientists that brings together file system tools and cloud technologies, (2) a service implementing this approach, called NeuronDepot, and (3) an example application of the service to a complex use case in the neurosciences. The main drivers for our approach are to facilitate collaborations with a transparent, automated data flow that shields scientists from having to learn new tools or data structuring paradigms. Using NeuronDepot is simple: one-time data assignment from the originator and cloud based syncing-thus making experimental and modeling data available across the collaboration with minimum overhead. Since data sharing is cloud based, our approach opens up the possibility of using new software developments and hardware scalabitliy which are associated with elastic cloud computing. We provide an implementation that relies on existing synchronization services and is usable from all devices via a reactive web interface. We are motivating our solution by solving the practical problems of the GinJang project, a collaboration of three universities across eight time zones with a complex workflow encompassing data from electrophysiological recordings, imaging, morphological reconstructions, and simulations.

  12. The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots

    Directory of Open Access Journals (Sweden)

    Camilla Siciliano

    2016-09-01

    Full Text Available Indirect evidence suggests that adipose tissue-derived stromal cells (ASCs possess different physiological and biological variations related to the anatomical localization of the adipose depots. Accordingly, to investigate the influence of the tissue origin on the intrinsic properties of ASCs and to assess their response to specific stimuli, we compared the biological, functional and ultrastructural properties of two ASC pools derived from mediastinal and subcutaneous depots (thoracic compartment by means of supplements such as platelet lysate (PL and FBS. Subcutaneous ASCs exhibited higher proliferative and clonogenic abilities than mediastinal counterpart, as well as increased secreted levels of IL-6 combined with lower amount of VEGF-C. In contrast, mediastinal ASCs displayed enhanced pro-angiogenic and adipogenic differentiation properties, increased cell diameter and early autophagic processes, highlighted by electron microscopy. Our results further support the hypothesis that the origin of adipose tissue significantly defines the biological properties of ASCs, and that a homogeneric function for all ASCs cannot be assumed.

  13. A multicenter, observational study of lanreotide depot/autogel (LAN) in patients with acromegaly in the United States: 2-year experience from the SODA registry.

    Science.gov (United States)

    Salvatori, Roberto; Gordon, Murray B; Woodmansee, Whitney W; Ioachimescu, Adriana G; Carver, Don W; Mirakhur, Beloo; Cox, David; Molitch, Mark E

    2017-12-01

    This analysis evaluates the 2-year effectiveness and safety of lanreotide depot/autogel (LAN), as well as treatment convenience and acromegaly symptom relief, from the Somatuline ® Depot for Acromegaly (SODA) registry, a post-marketing, open-label, observational, multicenter, United States registry study. Patients with acromegaly treated with LAN were eligible for enrollment. Demographics, LAN dose, extended dosing interval (EDI) (interval of injections ≥42 days), insulin-like growth factor 1 (IGF-1), growth hormone (GH), glycated hemoglobin, adverse events (AEs), injection convenience, and symptom data were collected. As of September 29, 2014, 241 patients were enrolled in SODA. IGF-1 levels below age- and gender-adjusted upper normal limit (ULN) were achieved in 71.2% at month (M) 12 and 74.4% at M24; GH ≤2.5 µg/L in 83.3% at M12 and 80.0% at M24; GH convenient. SODA indicates 2-year biochemical control with majority of patients achieving both IGF-1 < ULN and GH ≤2.5 µg/L. LAN was generally well tolerated with no new or unexpected safety signals reported during the observation period. clinicaltrials.gov Clinical Trial Identifier: NCT00686348.

  14. Functionalization of deproteinized bovine bone with a coating-incorporated depot of BMP-2 renders the material efficiently osteoinductive and suppresses foreign-body reactivity.

    Science.gov (United States)

    Wu, Gang; Hunziker, Ernst B; Zheng, Yuanna; Wismeijer, Daniel; Liu, Yuelian

    2011-12-01

    The repair of critical-sized bony defects remains a challenge in the fields of implantology, maxillofacial surgery and orthopaedics. As an alternative bone-defect filler to autologous bone grafts, deproteinized bovine bone (DBB) is highly osteoconductive and clinically now widely used. However, this product suffers from the disadvantage of not being intrinsically osteoinductive. In the present study, this property was conferred by coating DBB with a layer of calcium phosphate into which bone morphogenetic protein 2 (BMP-2) was incorporated. Granules of DBB bearing a coating-incorporated depot of BMP-2--together with the appropriate controls (DBB bearing a coating but no BMP-2; uncoated DBB bearing adsorbed BMP-2; uncoated DBB bearing no BMP-2)--were implanted subcutaneously in rats. Five weeks later, the implants were withdrawn for a histomorphometric analysis of the volume densities of (i) bone, (ii) bone marrow, (iii) foreign-body giant cells and (iv) fibrous capsular tissue. Parameters (i) and (ii) were highest, whilst parameters (iii) and (iv) were lowest in association with DBB bearing a coating-incorporated depot of BMP-2. Hence, this mode of functionalization not only confers DBB with the property of osteoinductivity but also improves its biocompatibility--thus dually enhancing its clinical potential in the repair of bony defects. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. Permanent Access to the Records of Science - The International Role of the e-Depot at the Koninklijke Bibliotheek, National Library of the Netherlands

    Directory of Open Access Journals (Sweden)

    Gerard van Trier

    2006-10-01

    Full Text Available In 1994 the Koninklijke Bibliotheek (KB decided to include electronic publications in its deposit collection. This was considered as a logical extension of the deposit for printed publications already in place. In December 2002, after a few years of experimenting, the current e-Depot was delivered, with the IBM Digital Information and Archiving System (DIAS as its technical 'heart'. The e-Depot is now fully operational and imbedded in the KB organisation. The emergence of the electronic journal creates new challenges to the traditional deposit model. Because of the involvement of international publishers of Dutch origin, the e-Depot has had an international dimension right from the start. In 2002 the KB signed an historic electronic archiving agreement with Elsevier Science, which covered the entire set of Elsevier journals. This arrangement turned the KB into the first official digital archive in the world for journals published by international scientific publishers. A year later the KB concluded a similar agreement with Kluwer Academic Publishers. Other publishers followed, also from outside the Netherlands: Biomed Central, Blackwell, Oxford University Press, Taylor and Francis, Sage, Springer and Brill Academic Publishers. On the basis of these agreements the e-Depot will eventually hold 9 million articles. The annual increase in the number of articles from these publishers will be around 400,000. Publishers are required to deposit their publications free of charge. Access is restricted: only on-site, for any registered user of the KB. Remote access is only offered with permission of the publisher. On-site retrieval, access, printing, downloading is for private use only, systematic reproduction is not allowed. Documents are available for interlibrary document supply within the Netherlands. The archive serves as a guarantee to all licensees worldwide. In case of calamities or in case the publisher does not meet his obligations, the KB

  16. East coast development overview : why now?

    International Nuclear Information System (INIS)

    Anderson, J.

    1998-01-01

    Progress achieved in developing East coast natural gas markets was discussed. Mobil, Shell, Imperial, Mosbacher and Nova Scotia Resources received the go-ahead for the Sable Offshore Energy Project last December. The owner companies created Sable Offshore Energy Inc. (SOE Inc.) for managing and operating the development. Mobil (which has 50 per cent of the total invested in the Sable offshore project) and their partners will spend an average of one million dollars per day in Nova Scotia over the next 22 months in order to ensure that they will deliver gas from the offshore site by late 1999. That is in addition to the 400 million dollars already spent by the consortium in the province of Nova Scotia. Job creation, of particular significance in the Atlantic provinces, is also expected to be a significant factor in lifting the GDP of Nova Scotia to three per cent in 1998. According to an estimate by the Bank of Nova Scotia, the Sable and pipeline projects alone will create more than 7,500 spin-off jobs. The five major factors which make eastern Canada development possible and economically attractive are: (1) resource potential, (2) technological advancements, (3) alliances, (4) market proximity, and (5) the rapidly expanding global market for natural gas. Each of these factors and how they impact on the East coast natural gas industry were discussed in some detail

  17. Pilot-Scale Demonstration of In-Situ Chemical Oxidation Involving Chlorinated Volatile Organic Compounds - Design and Deployment Guidelines (Parris Island, SC, U.S. Marine Corp Recruit Depot, Site 45 Pilot Study)

    Science.gov (United States)

    A pilot-scale in situ chemical oxidation (ISCO) demonstration, involving subsurface injections of sodium permanganate (NaMnO4), was performed at the US Marine Corp Recruit Depot (MCRD), site 45 (Parris Island (PI), SC). The ground water was originally contaminated with perchloroe...

  18. Attempt to evaluate the cumulative deposit of strontium 90 in several French centres; Essai d'evaluation du depot cumulatif de strontium 90 dans plusieurs stations francaises

    Energy Technology Data Exchange (ETDEWEB)

    Garnier, A [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires

    1966-07-01

    In order to be able to interpret results of radioactivity controls of the ambient atmosphere and of the supply chain carried out in several French centres, it is necessary to know the value of the cumulative strontium-90 deposit resulting from fall-out. The estimation of the fall-out which occurred locally in the years before systematic controls were established can be made by assuming that the {sup 90}Sr concentration in rain varies little from one place to another (if they are fairly close) and that the deposit can be deduced from that measured in a single station by making corrections for differences in the rainfall. This assumption is confirmed by applying the method to the calculation of {sup 90}Sr fall-out at Ispra, Mol and at several French centres: the values calculated are compared to those obtained by measurements carried out since 1958 in some cases, and since 1960 in others. The results show that the method is valid for calculating fall-out prior to 1960 (in the absence of information) and to deduce with sufficient approximation the subsequent cumulative deposits in the French centres under consideration. (author) [French] L'evaluation du depot cumulatif de Sr 90 consecutif aux retombees est necessaire a l'interpretation des resultats du controle de la radioactivite du milieu ambiant et de la cha e alimentaire effectue en plusieurs stations francaises. L'estimation des retombees locale des annees anterieures a la mise en oeuvre systematique des moyens de surveillance peut etre faite en admettant que la concentration de Sr 90 dans la pluie varie peu d'un endroit a l'autre (dans des regions assez rapprochees) et que le depot peut etre deduit de celui mesure en une station gr e a des corrections tenant compte de la variation de pluviosite. Cette hypothese est verifiee en appliquant la methode au calcul des retombees de Sr 90 a Ispra, a Mol, et en plusieurs stations francaises: les valeurs calculees sont comparees a celles obtenues par les mesures

  19. Opposite associations of trunk and leg fat depots with plasma ferritin levels in middle-aged and older Chinese men and women.

    Directory of Open Access Journals (Sweden)

    Hongyu Wu

    Full Text Available BACKGROUND: Few data have been published on the associations of ferritin with trunk and leg fat depots. We aimed to investigate these associations in a Chinese population. METHODOLOGY: Trunk fat mass and leg fat mass were determined in a cross-sectional sample of 1,150 Chinese (479 men and 671 women aged 50-70 years by dual-energy X-ray absorptiometry scan. Fasting plasma ferritin was measured. PRINCIPAL FINDINGS: Plasma ferritin was positively correlated with waist circumference, waist-to-hip ratio, total body fat and trunk fat mass, but inversely correlated with leg fat mass in men (r = 0.16, 0.26, 0.19, 0.22 and -0.12, respectively, all P<0.05 and women (r = 0.16, 0.16, 0.08, 0.17 and -0.12, respectively, all P<0.05. Multivariate regression analysis showed that ferritin levels increased with larger trunk fat mass (β = 0.33 ± 0.08 for men and β = 0.21 ± 0.05 for women, both P<0.001 while decreased with larger leg fat mass (β = -0.12 ± 0.09, P = 0.15 for men; and β = -0.14 ± 0.05, P = 0.005 for women. Moreover, plasma ferritin levels decreased with increasing tertile of leg fat mass among each tertile of trunk fat mass. CONCLUSION: This is the first study to report the opposite associations of trunk and leg fat depots with plasma ferritin levels.

  20. A Probabilistic Tool that Aids Logistics Engineers in the Establishment of High Confidence Repair Need-Dates at the NASA Shuttle Logistics Depot

    Science.gov (United States)

    Bullington, J. V.; Winkler, J. C.; Linton, D. G.; Khajenoori, S.

    1995-01-01

    The NASA Shuttle Logistics Depot (NSLD) is tasked with the responsibility for repair and manufacture of Line Replaceable Unit (LRU) hardware and components to support the Space Shuttle Orbiter. Due to shrinking budgets, cost effective repair of LRU's becomes a primary objective. To achieve this objective, is imperative that resources be assigned to those LRU's which have the greatest expectation of being needed as a spare. Forecasting the times at which spares are needed requires consideration of many significant factors including: failure rate, flight rate, spares availability, and desired level of support, among others. This paper summarizes the results of the research and development work that has been accomplished in producing an automated tool that assists in the assignment of effective repair start-times for LRU's at the NSLD. This system, called the Repair Start-time Assessment System (RSAS), uses probabilistic modeling technology to calculate a need date for a repair that considers the current repair pipeline status, as well as, serviceable spares and projections of future demands. The output from the system is a date for beginning the repair that has significantly greater confidence (in the sense that a desired probability of support is ensured) than times produced using other techniques. Since an important output of RSAS is the longest repair turn-around time that will ensure a desired probability of support, RSAS has the potential for being applied to operations at any repair depot where spares are on-hand and repair start-times are of interest. In addition, RSAS incorporates tenants of Just-in-Time (JIT) techniques in that the latest repair start-time (i.e., the latest time at which repair resources must be committed) may be calculated for every failed unit This could reduce the spares inventory for certain items, without significantly increasing the risk of unsatisfied demand.

  1. The Impact of Intra-articular Depot Betamethasone Injection on Insulin Resistance Among Diabetic Patients With Osteoarthritis of the Knee: A Case-Control Study.

    Science.gov (United States)

    Habib, George; Chernin, Mark; Sakas, Fahed; Artul, Suheil; Jabbour, Adel; Jabaly-Habib, Haneen

    2018-06-01

    The aim of this study was to evaluate the impact of intra-articular corticosteroid injection (IACI) of depot betamethasone at the knee joint on insulin resistance (IR). Patients with type 2 diabetes, non-insulin treated, with painful osteoarthritis of the knee were requested to participate in our study. After consent, demographic, clinical, and laboratory parameters were documented in addition to fasting blood glucose (FBG) and fasting blood insulin levels just prior to IACI of 1 mL of depot betamethasone. Fasting blood glucose and fasting blood insulin levels were repeated the next day following the IACI and 8 days later. Age- and sex-matched group of patients with type 2 diabetes from the same clinic were recruited as a control group (case-control study). Insulin resistance was calculated using Homeostasis Model Assessment-Insulin Resistance. Mann-Whitney U test, χ test, and Wilcoxon signed rank tests were used for statistical analysis. Eleven patients were recruited in the patients' group and 10 patients in the control group. Median FBG in the patients' group at baseline was 148 ± 51 mg/dL, and median IR was 5.12 ± 2.46. One day following the IACI, median FBG level was 247 ± 104 mg/dL (P = 0.004, compared with baseline), with median IR of 20.8 ± 7.01 (P = 0.0039). The median ratios of blood glucose and IR 1 day following the IACI compared with baseline were 1.7 and 4.1, respectively. Eight days following the IACI, mean FBG and IR levels were not significantly different from baseline. Intra-articular corticosteroid injection of betamethasone at the knee joint among patients with diabetes was associated with a significant increase in IR levels compared with baseline levels, 1 day following the injection. The mean percentage of increase in IR was higher than that for FBG levels.

  2. Biological-Physical Coupling in the Gulf of Maine: Satellite and Model Studies of Phytoplankton Variability

    Science.gov (United States)

    Thomas, Andrew C.; Chai, F.; Townsend, D. W.; Xue, H.

    2002-01-01

    The goals of this project were to acquire, process, QC, archive and analyze SeaWiFS chlorophyll fields over the Gulf of Maine and Scotia Shelf region. The focus of the analysis effort was to calculate and quantify seasonality and interannual. variability of SeaWiFS-measured phytoplankton biomass in the study area and compare these to physical forcing and hydrography. An additional focus within this effort was on regional differences within the heterogeneous biophysical regions of the Gulf of Maine / Scotia Shelf. Overall goals were approached through the combined use of SeaWiFS and AVHRR data and the development of a coupled biology-physical numerical model.

  3. The offshore accords and Hibernia's impact on the Newfoundland treasury

    International Nuclear Information System (INIS)

    Locke, W.

    1992-01-01

    The provincial governments of Newfoundland and Nova Scotia have each signed an accord with the government of Canada to manage and share revenues from the development of their respective offshore oil and gas fields. Negotiated provisions for offsetting equalization payments were an important component of each of these accords. The potential effectiveness of these provisions in sheltering offshore oil revenues derived from the Hibernia project under various oil price scenarios is reviewed. Both mathematical and simulation analyses demonstrate that the provisions negotiated by Nova Scotia shelter significantly more revenue than those by Newfoundland. Recommendations for future negotiating positions are presented. 4 refs., 3 tabs

  4. Technical summaries of Scotian Shelf - significant and commercial discoveries

    International Nuclear Information System (INIS)

    Dickey, J.E.; Bigelow, S.F.; Edens, J.A.; Brown, D.E.; Smith, B.; Makrides, C.; Mader, R.

    1997-03-01

    An independent assessment of the recoverable hydrocarbon resource currently held under' Significant and Commercial Discovery' status offshore Nova Scotia was presented. A generalized description of the regulatory issues regarding the discovered resources within the Scotian Basin was included. Twenty discoveries have been declared significant and two have been declared commercial, pursuant to the Canada-Nova Scotia Offshore Petroleum Resources Accord Implementation Acts. Salient facts about each discovery were documented. The information included the wells drilled within the structure, significant flow tests, geological and geophysical attributes, structural cross-section and areal extent, petrophysical parameters, hydrocarbons in place and anticipated hydrocarbon recoverable resource. tabs., figs

  5. Intramuscular depot formulations of leuprolide acetate suppress testosterone levels below a 20 ng/dL threshold: a retrospective analysis of two Phase III studies

    Directory of Open Access Journals (Sweden)

    Spitz A

    2016-08-01

    Full Text Available Aaron Spitz,1 Marc Gittelman,2 Lawrence I Karsh,3 Sanja Dragnic,4 Ahmed M Soliman,5 Aditya Lele,6 Damian Gruca,7 Michael Norton4 1Orange County Urology Associates, Laguna Beach, CA, 221st Century Oncology/UroMedix-Aventura Division, Aventura, FL, 3The Urology Center of Colorado, Denver, CO, 4US Medical Affairs, 5Health Economics and Outcomes Research, 6Data and Statistical Sciences, AbbVie Inc., North Chicago, IL, USA; 7Global Medical Affairs, AbbVie Deutschland, Ludwigshafen, Germany Introduction: Androgen deprivation therapy (ADT with gonadotropin-releasing hormone (GnRH analogs is a standard treatment for advanced prostate cancer. GnRH analog therapy can reduce testosterone to “castrate” levels, historically defined as <50 ng/dL. With the advent of newer assays, a lower threshold of <20 ng/dL has recently been proposed. We report the results of a retrospective analysis of two Phase III trials of 4- and 6-month depot microsphere formulations of leuprolide acetate (LA, a GnRH agonist that has previously demonstrated efficacy in testosterone suppression to <50 ng/dL in patients on ADT. This analysis investigates the ability of these LA formulations to suppress to ≤20 ng/dL levels.Methods: In two of five AbbVie/Abbott clinical trials of microsphere formulations of LA for ADT, analytic technology permitting testosterone detection as low as 3 ng/dL was used and thus was selected for this analysis. Both trials were open-label, fixed-dose studies in prostate cancer patients, naïve to ADT. Patients received either 30 mg (4-month formulation; n=49 or 45 mg (6-month formulation; n=151 depot injections of LA microspheres. Treatment duration was up to 32 weeks for the 4-month formulation and 48 weeks for the 6-month formulation. The proportion of patients achieving the 20 ng/dL threshold was determined every 4 weeks.Results: Pooled analysis showed that 152 of 193 (79% of patients achieved serum testosterone levels of ≤20 ng/dL at 4 weeks, and

  6. Influence of adipocyte size and adipose depot on the in vitro lipolytic activity and insulin sensitivity of adipose tissue in dairy cows at the end of the dry period.

    Science.gov (United States)

    De Koster, J; Van den Broeck, W; Hulpio, L; Claeys, E; Van Eetvelde, M; Hermans, K; Hostens, M; Fievez, V; Opsomer, G

    2016-03-01

    The aim of the present research was to describe characteristics of adipose tissue lipolysis in dairy cows with a variable body condition score (BCS). Ten clinically healthy Holstein Friesian cows were selected based on BCS and euthanized 10 to 13 d before the expected parturition date. Immediately after euthanasia, adipose tissue samples were collected from subcutaneous and omental fat depots. In both depots, we observed an increase in adipocyte size with increasing BCS. Using an in vitro explant culture of subcutaneous and omental adipose tissue, we aimed to determine the influence of adipocyte size and localization of adipose depot on the lipolytic activity in basal conditions and after addition of isoproterenol (nonselective β-agonist) and insulin in different concentrations. Glycerol release in the medium was used as a measure for lipolytic activity. We observed that the basal lipolytic activity of subcutaneous and omental adipose tissue increased with adipocyte volume, meaning that larger fat cells have higher basal lipolytic activity independent of the location of the adipose depot. Dose-response curves were created between the concentration of isoproterenol or insulin and the amount of glycerol released. The shape of the dose-response curves is determined by the concentration of isoproterenol and insulin needed to elicit the half-maximal effect and the maximal amount of stimulated glycerol release or the maximal inhibitory effect of insulin. We observed that larger fat cells released more glycerol upon maximal stimulation with isoproterenol and this was more pronounced in subcutaneous adipose tissue. Additionally, larger fat cells had a higher sensitivity toward lipolytic signals. We observed a trend for larger adipocytes to be more resistant to the maximal antilipolytic effect of insulin. The insulin concentration needed to elicit the half-maximal inhibitory effect of insulin was within the physiological range of insulin and was not influenced by adipocyte

  7. Comparison of Continuation Rates and Reasons of Discontinuation for Cyclofem and Depot -medroxyprogesterone acetate in Rural Areas of East Azerbaijan Province, Iran

    Directory of Open Access Journals (Sweden)

    Robab Hassanzadeh

    2012-03-01

    Full Text Available Objective: In this study continuation rate and reasons for discontinuation of Depot-medroxyprogestroneacetate (DMPAand Cyclofem have been compared.Materials and methods: A retrospective cohort study was conducted with 422 women (202 Cyclofemand220 DMPA userswho had started using the methods 12-24 months before the study in East Azerbaijanhealth houses. Data were collected by reviewing the records and interview with the clients and analysedusing Kaplan-Meier and Cox Regression.Results: The 3, 6, 9, 12 months continuation rate were 56%, 37%, 30%, 27% respectively for Cyclofemversus 75%, 59.5%, 48%, 42.5% for DMPA. Menstrual changes were reported significantly more by theDMPA users than the Cyclofem users (85% vs. 73%, P=0.008 as the main reason for thediscontinuation, the difference mainly reflected of amenorrhea (50% vs. 23%, P=0.003. None of DMPAusers and 11% of Cyclofem users claimed frequency of visits and lack of method supplies as their maindiscontinuation reason.Conclusion: Discontinuation rate was high for the both methods but it was higher for Cyclofem.Thecommon side effects mentioned as the main reasons for discontinuation of the both methods are nothealth threatening. Therefore, health care providers may help to improve their continuation rate byappropriate consultation.

  8. One-week glucose control via zero-order release kinetics from an injectable depot of glucagon-like peptide-1 fused to a thermosensitive biopolymer.

    Science.gov (United States)

    Luginbuhl, Kelli M; Schaal, Jeffrey L; Umstead, Bret; Mastria, Eric M; Li, Xinghai; Banskota, Samagya; Arnold, Susan; Feinglos, Mark; D'Alessio, David; Chilkoti, Ashutosh

    2017-01-01

    Stimulation of the glucagon-like peptide-1 (GLP1) receptor is a useful treatment strategy for type 2 diabetes because of pleiotropic effects, including the regulation of islet hormones and the induction of satiety. However, the native ligand for the GLP1 receptor has a short half-live owing to enzymatic inactivation and rapid clearance. Here, we show that a subcutaneous depot formed after a single injection of GLP1 recombinantly fused to a thermosensitive elastin-like polypeptide results in zero-order release kinetics and circulation times of up to 10 days in mice and 17 days in monkeys. The optimized pharmacokinetics leads to 10 days of glycemic control in three different mouse models of diabetes, as well as to the reduction of glycosylated hemoglobin levels and weight gain in ob/ob mice treated once weekly for 8 weeks. Our results suggest that the optimized GLP1 formulation could enhance therapeutic outcomes by eliminating peak-and-valley pharmacokinetics and improving overall safety and tolerability. The design principles that we established should be broadly applicable for improving the pharmacological performance of other peptide and protein therapeutics.

  9. Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging-measured adipose tissue depots in both HIV-infected and control subjects.

    Science.gov (United States)

    Scherzer, Rebecca; Shen, Wei; Bacchetti, Peter; Kotler, Donald; Lewis, Cora E; Shlipak, Michael G; Heymsfield, Steven B; Grunfeld, Carl

    2008-06-01

    Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects. We compared anthropometric and magnetic resonance imaging (MRI)-based adiposity measures as correlates of metabolic complications of adiposity in HIV-infected and control subjects. The study was a cross-sectional analysis of 666 HIV-positive and 242 control subjects in the Fat Redistribution and Metabolic Change in HIV Infection (FRAM) study assessing body mass index (BMI), waist (WC) and hip (HC) circumferences, waist-to-hip ratio (WHR), %BF, and MRI-measured regional adipose tissue. Study outcomes were 3 metabolic risk variables [homeostatic model assessment (HOMA), triglycerides, and HDL cholesterol]. Analyses were stratified by sex and HIV status and adjusted for demographic, lifestyle, and HIV-related factors. In HIV-infected and control subjects, univariate associations with HOMA, triglycerides, and HDL were strongest for WC, MRI-measured visceral adipose tissue, and WHR; in all cases, differences in correlation between the strongest measures for each outcome were small (r HDL, WC appeared to be the best anthropometric correlate of metabolic complications, whereas, for triglycerides, the best was WHR. Relations of simple anthropometric measures with HOMA, triglycerides, and HDL cholesterol are approximately as strong as MRI-measured whole-body adipose tissue depots in both HIV-infected and control subjects.

  10. The role of social cost-benefit analysis in societal decision-making under large uncertainties with application to robbery at a cash depot

    International Nuclear Information System (INIS)

    Jones-Lee, M.; Aven, T.

    2009-01-01

    Social cost-benefit analysis is a well-established method for guiding decisions about safety investments, particularly in situations in which it is possible to make accurate predictions of future performance. However, its direct applicability to situations involving large degrees of uncertainty is less obvious and this raises the question of the extent to which social cost-benefit analysis can provide a useful input to the decision framework that has been explicitly developed to deal with safety decisions in which uncertainty is a major factor, namely risk analysis. This is the main focus of the arguments developed in this paper. In particular, we provide new insights by examining the fundamentals of both approaches and our principal conclusion is that social cost-benefit analysis and risk analysis represent complementary input bases to the decision-making process, and even in the case of large uncertainties social cost-benefit analysis may provide very useful decision support. What is required is the establishment of a proper contextual framework which structures and gives adequate weight to the uncertainties. An application to the possibility of a robbery at a cash depot is examined as a practical example.

  11. Effect of Injection Minimal Dosages of Depot Medroxyprogesterone acetate (DMPA to Body Weight and Blood Chemistry Male Rat Strain Sprague-Dawley

    Directory of Open Access Journals (Sweden)

    Nukman Moeloek

    2009-11-01

    Full Text Available Many family planning program focus more on men. Until now, vasectomy has been the commonly used method for male contraception. However, this method creates inconvenience such as irreversibility and psychological problems. One of the alternatives contraception is the combination of depot medroxyprogesterone acetate (DMPA and androgen. The minimum dosage of DMPA could suppress testosterone level that leads to reduced spermatogenesis and sperm viability. Nevertheless, until now it is not known whether minimum dosages of DMPA have an effect to body weight and blood chemistry. Therefore, this research aimed at determinate the effect of minimal dosages of DMPA to body mass and blood chemistry using male rats (Rattus norvegicus L. strain Sprague-Dawley as model. This research using completely randomized design, unequal size sample, castration treatments and several doses DMPA (1.25, 0.625, and 0.313 milligram. Injecting of DMPA conducted intramuscularly on week 0 and week 12. Normality/homogeneity Data normality were analyzed before ANOVA test. Then, abnormal data were tested using Kruskal-Wallis test. The result shows that injection of DMPA in various doses do not have an effect on body weight and blood chemistry such as erytrocytes, haemoglobin, hematocrite, HDL, LDL, total cholesterol, SGOT, SGPT and triglyseride (p>0,05. Furthermore, it is concluded that that no effect of minimal dosages of DMPA to body mass and blood chemistry of rat.

  12. The Washington Needle Depot: fitting healthcare to injection drug users rather than injection drug users to healthcare: moving from a syringe exchange to syringe distribution model

    Directory of Open Access Journals (Sweden)

    Glickman Andrea

    2010-01-01

    Full Text Available Abstract Needle exchange programs chase political as well as epidemiological dragons, carrying within them both implicit moral and political goals. In the exchange model of syringe distribution, injection drug users (IDUs must provide used needles in order to receive new needles. Distribution and retrieval are co-existent in the exchange model. Likewise, limitations on how many needles can be received at a time compel addicts to have multiple points of contact with professionals where the virtues of treatment and detox are impressed upon them. The centre of gravity for syringe distribution programs needs to shift from needle exchange to needle distribution, which provides unlimited access to syringes. This paper provides a case study of the Washington Needle Depot, a program operating under the syringe distribution model, showing that the distribution and retrieval of syringes can be separated with effective results. Further, the experience of IDUs is utilized, through paid employment, to provide a vulnerable population of people with clean syringes to prevent HIV and HCV.

  13. In situ depot comprising phase-change materials that can sustainably release a gasotransmitter H2S to treat diabetic wounds.

    Science.gov (United States)

    Lin, Wei-Chih; Huang, Chieh-Cheng; Lin, Shu-Jyuan; Li, Meng-Ju; Chang, Yen; Lin, Yu-Jung; Wan, Wei-Lin; Shih, Po-Chien; Sung, Hsing-Wen

    2017-11-01

    Patients with diabetes mellitus are prone to develop refractory wounds. They exhibit reduced synthesis and levels of circulating hydrogen sulfide (H 2 S), which is an ephemeral gaseous molecule. Physiologically, H 2 S is an endogenous gasotransmitter with multiple biological functions. An emulsion method is utilized to prepare a microparticle system that comprises phase-change materials with a nearly constant temperature of phase transitions to encapsulate sodium hydrosulfide (NaHS), a highly water-labile H 2 S donor. An emulsion technique that can minimize the loss of water-labile active compounds during emulsification must be developed. The as-prepared microparticles (NaHS@MPs) provide an in situ depot for the sustained release of exogenous H 2 S under physiological conditions. The sustained release of H 2 S promotes several cell behaviors, including epidermal/endothelial cell proliferation and migration, as well as angiogenesis, by extending the activation of cellular ERK1/2 and p38, accelerating the healing of full-thickness wounds in diabetic mice. These experimental results reveal the strong potential of NaHS@MPs for the sustained release of H 2 S for the treatment of diabetic wounds. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Quantity and quality of guinea pig (cavia porcellus) spermatozoa after administration of methanol extract of bitter melon (momordica charantia) seed and depot medroxy progesterone acetate (DMPA)

    Science.gov (United States)

    Ilyas, Syafruddin; Hutahaean, Salomo; Nursal

    2018-03-01

    The discovery of male contraceptive drugs continues to be pursued, due to the few participation of men associated with the lack of contraceptive options for men. The combination of bitter melon seed methanol extract and DMPA are the options that currently apply to men. Therefore, the use of guinea pigs as experimental animals conducted research using experimental methods with complete randomized design (CRD). There are 4 control groups and 4 treatment groups. The first group, control group of dimethyl sulphoxide (DMSO) for 0 week (K0), The second one, bitter melon seed extract of 50 mg/100g Body Weight/day for 0 week (P0), the third one, control group of dimethyl sulfoxide (DMSO) for 4 weeks (K1), the fourth one, bitter melon seed extract of 50 mg/100g BW/day for 4 weeks + Depot medroxy Progesterone Acetate (P1), the fifth one, control group of dimethyl sulfoxide (DMSO) for 8 weeks (K2), the sixth one, bitter melon seed extract of 50 mg/100g BW/day for 8 weeks + DMPA (P2), the seventh one, control group of dimethyl sulfoxide (DMSO) for 12 weeks (K3), the eighth one, bitter melon seed extract of 50 mg/100g BW/day for 12 weeks + DMPA (P3). Methanol extract of bitter melon seed to decrease the quantity and quality of guinea pig spermatozoa decreased significantly, i.e. viability and normal morphology of spermatozoa (p<0.05).

  15. Longitudinal profiling of the tissue-specific expression of genes related with insulin sensitivity in dairy cows during lactation focusing on different fat depots.

    Directory of Open Access Journals (Sweden)

    Behnam Saremi

    Full Text Available In dairy cows the milk associated energy output in early lactation exceeds the input via voluntary feed intake. To spare glucose for mammary lactose synthesis, peripheral insulin sensitivity (IS is reduced and fat mobilization is stimulated. For these processes a link between IS and the endocrine functions of adipose tissue (AT is likely; we thus aimed to characterise the mRNA expression from bovine AT derived proteins and receptors that are related to IS according to the literature in metabolically active tissues plus systemic IS throughout lactation. Conjugated linoleic acids (CLA reduce milk fat thus decreasing the milk drain of energy and potentially dampening lipolysis, but may also affect IS. Subcutaneous (s.c. AT and liver from pluriparous cows receiving either control fat or CLA supplement (100 g/day from 1 to 182 days in milk each were biopsied covering week -3 to 36 relative to parturition. In an additional trial with primiparous cows treated analogously and slaughtered on days in milk 1, 42 or 105, samples from liver, udder, skeletal muscle and 3 visceral and 3 s.c. AT were obtained and assayed for mRNA abundance of adiponectin, its receptors, leptin, leptin receptor, PPARγ, PPARγ2, IL-6, and TNF-α. In pluriparous animals, the mRNA abundance of most of the target genes decreased after parturition in s.c. AT but increased in liver. In primiparous cows, AT depot specific differences were mostly related to retroperitoneal AT; adiponectin receptor 1 and TNF-α were affected predominantly. CLA effects in primiparous cows were largely limited to decreased PPARγ2 mRNA abundance in udder tissue. In pluriparous cows, insulin secretion was increased by CLA resulting in decreased systemic IS but without consistent changes in tissue target mRNA abundance. The temporal gene expression profiles from the adipokines and related receptors support their coactive function in adapting to the needs of lactation.

  16. Longitudinal Profiling of the Tissue-Specific Expression of Genes Related with Insulin Sensitivity in Dairy Cows during Lactation Focusing on Different Fat Depots

    Science.gov (United States)

    Saremi, Behnam; Winand, Sarah; Friedrichs, Paula; Kinoshita, Asako; Rehage, Jürgen; Dänicke, Sven; Häussler, Susanne; Breves, Gerhard; Mielenz, Manfred; Sauerwein, Helga

    2014-01-01

    In dairy cows the milk associated energy output in early lactation exceeds the input via voluntary feed intake. To spare glucose for mammary lactose synthesis, peripheral insulin sensitivity (IS) is reduced and fat mobilization is stimulated. For these processes a link between IS and the endocrine functions of adipose tissue (AT) is likely; we thus aimed to characterise the mRNA expression from bovine AT derived proteins and receptors that are related to IS according to the literature in metabolically active tissues plus systemic IS throughout lactation. Conjugated linoleic acids (CLA) reduce milk fat thus decreasing the milk drain of energy and potentially dampening lipolysis, but may also affect IS. Subcutaneous (s.c.) AT and liver from pluriparous cows receiving either control fat or CLA supplement (100 g/day from 1 to 182 days in milk each) were biopsied covering week −3 to 36 relative to parturition. In an additional trial with primiparous cows treated analogously and slaughtered on days in milk 1, 42 or 105, samples from liver, udder, skeletal muscle and 3 visceral and 3 s.c. AT were obtained and assayed for mRNA abundance of adiponectin, its receptors, leptin, leptin receptor, PPARγ, PPARγ2, IL-6, and TNF-α. In pluriparous animals, the mRNA abundance of most of the target genes decreased after parturition in s.c. AT but increased in liver. In primiparous cows, AT depot specific differences were mostly related to retroperitoneal AT; adiponectin receptor 1 and TNF-α were affected predominantly. CLA effects in primiparous cows were largely limited to decreased PPARγ2 mRNA abundance in udder tissue. In pluriparous cows, insulin secretion was increased by CLA resulting in decreased systemic IS but without consistent changes in tissue target mRNA abundance. The temporal gene expression profiles from the adipokines and related receptors support their coactive function in adapting to the needs of lactation. PMID:24465964

  17. Effect of treatment with depot somatostatin analogue octreotide on primary hyperparathyroidism (PHP) in multiple endocrine neoplasia type 1 (MEN1) patients.

    Science.gov (United States)

    Faggiano, Antongiulio; Tavares, Lidice Brandao; Tauchmanova, Libuse; Milone, Francesco; Mansueto, Gelsomina; Ramundo, Valeria; De Caro, Maria Laura Del Basso; Lombardi, Gaetano; De Rosa, Gaetano; Colao, Annamaria

    2008-11-01

    In patients with multiple endocrine neoplasia type 1 (MEN1), expression of somatostatin receptor (SST) in parathyroid adenomas and effectiveness of therapy with somatostatin analogues on primary hyperparathyroidism (PHP) have been scarcely investigated. To evaluate the effects of depot long acting octreotide (OCT-LAR) in patients with MEN1-related PHP. Eight patients with a genetically confirmed MEN1, presenting both PHP and duodeno-pancreatic neuroendocrine tumours (NET), were enrolled. The initial treatment was OCT-LAR 30 mg every 4 weeks. This therapy was established to stabilize the duodeno-pancreatic NET before to perform parathyroidectomy for PHP. Before OCT-LAR therapy, a SST scintigraphy was performed in all patients. SST subtype 2A immunohistochemistry was performed on parathyroid tumour samples from three patients undergone parathyroidectomy after OCT-LAR therapy. Serum concentrations of PTH, calcium and phosphorus as well as the 24-h urine calcium : creatinine ratio and the renal threshold phosphate concentration were evaluated before and after OCT-LAR. After OCT-LAR therapy, hypercalcaemia and hypercalciuria normalized in 75% and 62.5% of patients, respectively, and serum phosphorus and renal threshold phosphate significantly increased. Serum PTH concentrations significantly decreased in all patients and normalized in two of them. SST subtype 2A immunostaining was found in all parathyroid adenomas investigated, while SST scintigraphy showed a positive parathyroid tumour uptake in three of eight patients (37.5%). Six months of OCT-LAR therapy controlled hypercalcaemia and hypercalciuria in two-thirds of patients with MEN1-related PHP. Direct OCT-LAR effects mediated by binding to SST expression on parathyroid tumour cells are likely the main mechanism to explain the activity of this compound on calcium and phosphorus abnormalities in MEN1 PHP.

  18. Comparison of dual-energy X-ray absorptiometry and magnetic resonance imaging-measured adipose tissue depots in HIV-infected and control subjects.

    Science.gov (United States)

    Scherzer, Rebecca; Shen, Wei; Bacchetti, Peter; Kotler, Donald; Lewis, Cora E; Shlipak, Michael G; Punyanitya, Mark; Heymsfield, Steven B; Grunfeld, Carl

    2008-10-01

    Studies in persons without HIV infection have compared adipose tissue measured by dual-energy X-ray absorptiometry (DXA) and magnetic resonance imaging (MRI), but no such study has been conducted in HIV-infected (HIV+) subjects, who have a high prevalence of regional fat loss. We compared DXA- with MRI-measured trunk, leg, arm, and total fat in HIV+ and control subjects. A cross-sectional analysis was conducted in 877 HIV+ subjects and 260 control subjects in FRAM (Study of Fat Redistribution and Metabolic Change in HIV Infection), stratified by sex and HIV status. Univariate associations of DXA with MRI were strongest for total and trunk fat (r > or = 0.92) and slightly weaker for leg (r > or = 0.87) and arm (r > or = 0.71) fat. The average estimated limb fat was substantially greater for DXA than for MRI for HIV+ and control men and women (all P < 0.0001). Less of a difference was observed in trunk fat measured by DXA and MRI, but the difference was still statistically significant (P < 0.0001). Bland-Altman plots showed increasing differences and variability. Greater average limb fat in control and HIV+ subjects (both P < 0.0001) was associated with greater differences between DXA and MRI measurements. Because the control subjects had more limb fat than did the HIV+ subjects, greater amounts of fat were measured by DXA than by MRI when control subjects were compared with HIV+ subjects. More HIV+ subjects had leg fat in the bottom decile of the control subjects by DXA than by MRI (P < 0.0001). Although DXA- and MRI-measured adipose tissue depots correlate strongly in HIV+ and control subjects, differences increase as average fat increases, particularly for limb fat. DXA may estimate a higher prevalence of peripheral lipoatrophy than does MRI in HIV+ subjects.

  19. Simple anthropometric measures correlate with metabolic risk indicators as strongly as magnetic resonance imaging–measured adipose tissue depots in both HIV-infected and control subjects2

    Science.gov (United States)

    Scherzer, Rebecca; Shen, Wei; Bacchetti, Peter; Kotler, Donald; Lewis, Cora E; Shlipak, Michael G; Heymsfield, Steven B

    2008-01-01

    Background Studies in persons without HIV infection have compared percentage body fat (%BF) and waist circumference as markers of risk for the complications of excess adiposity, but only limited study has been conducted in HIV-infected subjects. Objective We compared anthropometric and magnetic resonance imaging (MRI)–based adiposity measures as correlates of metabolic complications of adiposity in HIV-infected and control subjects. Design The study was a cross-sectional analysis of 666 HIV-positive and 242 control subjects in the Fat Redistribution and Metabolic Change in HIV Infection (FRAM) study assessing body mass index (BMI), waist (WC) and hip (HC) circumferences, waist-to-hip ratio (WHR), %BF, and MRI-measured regional adipose tissue. Study outcomes were 3 metabolic risk variables [homeostatic model assessment (HOMA), triglycerides, and HDL cholesterol]. Analyses were stratified by sex and HIV status and adjusted for demographic, lifestyle, and HIV-related factors. Results In HIV-infected and control subjects, univariate associations with HOMA, triglycerides, and HDL were strongest for WC, MRI-measured visceral adipose tissue, and WHR; in all cases, differences in correlation between the strongest measures for each outcome were small (r ≤ 0.07). Multivariate adjustment found no significant difference for optimally fitting models between the use of anthropometric and MRI measures, and the magnitudes of differences were small (adjusted R2 ≤ 0.06). For HOMA and HDL, WC appeared to be the best anthropometric correlate of metabolic complications, whereas, for triglycerides, the best was WHR. Conclusion Relations of simple anthropometric measures with HOMA, triglycerides, and HDL cholesterol are approximately as strong as MRI-measured whole-body adipose tissue depots in both HIV-infected and control subjects. PMID:18541572

  20. Effectiveness, pharmacokinetics, and safety of a new sustained-release leuprolide acetate 3.75-mg depot formulation for testosterone suppression in patients with prostate cancer: a Phase III, open-label, international multicenter study.

    Science.gov (United States)

    Marberger, Michael; Kaisary, Amir V; Shore, Neal D; Karlin, Gary S; Savulsky, Claudio; Mis, Ricard; Leuratti, Chiara; Germa, Josep R

    2010-04-01

    A microencapsulated, sustained-release formulation of leuprolide acetate 3.75 mg has been developed. This study investigated the effectiveness, pharmacokinetics, and safety profile of a 1-month leuprolide acetate 3.75-mg depot formulation for suppressing testosterone concentrations in patients with prostate cancer. This was a Phase III, open-label, international multicenter clinical trial. Patients with prostate cancer who, in the judgment of the investigators, could benefit from androgen deprivation therapy received 6 monthly intramuscular injections of leuprolide acetate 3.75-mg depot. Plasma testosterone concentrations were determined at specific times throughout the study. The primary end point was the proportion of successful patients over the total number of evaluable patients (ie, patients with evaluable testosterone concentrations at all monthly assessments and no missing values due to treatment-related adverse events). Treatment success was defined as testosterone suppression below the clinical castration level (ie, n = 12), showed sustained release of leuprolide from the formulation. Values for AUC(0-t) calculated from day 0 to day 28, days 28 to 56, and days 56 to 84 were 25,976.5 (7892.0), 30,685.5 (9348.4), and 31,030.9 (10,745.0) pg/mL per day, respectively. The most common treatment-related adverse event was hot flashes (45.0% [72/160]). Fatigue, hyperhidrosis, night sweats, and headache each occurred in depot was effective in achieving and maintaining testosterone suppression and was well tolerated throughout the study in this cohort of patients with prostate cancer. ClinicalTrials.gov identifier: NCT00128531.

  1. Deposition of pyrolytic carbon from methane in the pores of artificial graphites. Influence of the temperature (1961); Depot de carbone pyrolytique dans les pores de graphites artificiels a partir de methane. Influence de la temperature (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Blanchard, R; Bochirol, L; Moreau, C; Philippot, J [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1961-07-01

    it is shown that below 1000 deg. C the carbon formed by the decomposition of methane is deposited at a depth of up to several centimetres in the porosity of graphitic supports; the probable mechanism of these reactions is given. (authors) [French] On montre qu'en dessous de 1000 deg. C le depot de carbone par decomposition de methane se produit jusqu'a une profondeur de plusieurs dizaines de millimetres dans la porosite de supports graphites, et l'on indique le mecanisme probable de ces reactions. (auteurs)

  2. Diet Quality and Academic Performance

    Science.gov (United States)

    Florence, Michelle D.; Asbridge, Mark; Veugelers, Paul J.

    2008-01-01

    Background: Although the effects of nutrition on health and school performance are often cited, few research studies have examined the effect of diet quality on the academic performance of children. This study examines the association between overall diet quality and academic performance. Methods: In 2003, 5200 grade 5 students in Nova Scotia,…

  3. Another year of change for Canadian electric utilities as they continue to meet new challenges

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    The activities of Canadian electric utilities in the past year were highlighted. The companies reviewed were: B.C. Hydro, Edmonton Power, TransAlta Utilities Corporation, Manitoba Hydro, Ontario Hydro, Hydro-Quebec, New Brunswick Power Corporation, Nova Scotia Power Inc., and Newfoundland Power. Reviews of the industry, economic growth, market trends and forecasts were discussed

  4. Trajectories of Smooth: The Multidimensionality of Spatial Relations and Autism Spectrum

    Science.gov (United States)

    Reddington, Sarah; Price, Deborah

    2017-01-01

    This paper examines how two men with autism spectrum (AS) experience educational spaces having attended public school in Nova Scotia, Canada. Smooth and striated space is mobilised as the main conceptual framework to account for the men's affectivities when experiencing the educational terrain. The central aim when applying smooth and striated…

  5. Cyborg and Autism: Exploring New Social Articulations via Posthuman Connections

    Science.gov (United States)

    Reddington, Sarah; Price, Deborah

    2016-01-01

    This paper explores the connections a young man with autism spectrum (AS) made using cyborg imagery having attended school in Nova Scotia, Canada. Cyborg is applied as a conceptual approach to explore the young man's connections to human and nonhuman elements. We also make use of rhizomes as a methodological framework to support the exploration of…

  6. Distribution of mercury in archived fur from little brown bats across Atlantic Canada

    International Nuclear Information System (INIS)

    Little, Megan E.; Burgess, Neil M.; Broders, Hugh G.; Campbell, Linda M.

    2015-01-01

    Total mercury (Hg) concentrations were measured in archived fur from adult female little brown bats sampled at maternity roosts across Atlantic Canada. Mercury concentrations varied significantly among regions and roosts. Bats from Nova Scotia and Newfoundland had the highest median Hg concentrations (9.67 μg/g and 9.51 μg/g) among regions, and individuals from Kejimkujik National Park had the highest Hg (median: 28.38 μg/g) among roosts. Over one third of individuals sampled had fur Hg concentrations exceeding thresholds associated with neurochemical responses. Within-roost examinations of stable carbon and nitrogen isotopes in fur showed inconsistent associations with Hg concentrations. Therefore, the hypothesis that within-roost variation in Hg is driven by variation in diet is not supported by this data, and it is recommended that key prey items be included in future mercury bioaccumulation studies for bats. The elevated mercury fur concentrations for bats from southern Nova Scotia remains an anomaly of concern even when placed in the larger context of Atlantic Canada. - Highlights: • Nova Scotia and Newfoundland bats had the highest median Hg values in fur among regions. • Median maternity roost fur Hg concentrations were highest in Kejimkujik, Nova Scotia. • Hg concentrations in 37% of bats exceeded the threshold for neurochemical responses. • Within-roost variations in carbon and nitrogen stable isotopes do not match Hg trends.

  7. Behaviour of nickel, copper, zinc and cadmium in the upper 300 m of a transect in the Southern Ocean (57°-62°S, 49°W)

    NARCIS (Netherlands)

    Nolting, R.F.; Baar, H.J.W. de

    1994-01-01

    The distributions of Ni, Cu, Zn and Cd in relation to phosphate, nitrate and silicate in the upper 300 m of a transect in the Southern Ocean were studied. This transect covers the Scotia Sea, the Confluence and the Weddell Sea. These three watermasses are clearly separated by their temperature and

  8. Sustainability Statement and Policy

    Science.gov (United States)

    Journal of Education for Sustainable Development, 2009

    2009-01-01

    This article presents nine resources that focus on environmental education and sustainability. These include: (1) "Sustainability Statement and Policy," Dalhousie University, Nova Scotia, Canada, 2009, which is available at http://office.sustainability.dal.ca/Governance; (2) "Climate Literacy: The Essential Principles of Climate…

  9. Visual Sensitivities and Discriminations and Their Roles in Aviation.

    Science.gov (United States)

    1985-06-17

    University Halifax, Nova Scotia /Oa Canada R3H 4H6 -i. CONTROLLING OFFICE NAME AND ADDRESS 12. REPORT DATE Life Sciences Directorate 17 June 1985 Air...acuity of about 0.2 deg when viewing is binocular (Beverley & Regan, 1975). It has been Daihousie Uiversity 11 Departments of Ophthalmology and Medicine

  10. Effectiveness of a Novel Community-Based Early Intervention Model for Children with Autistic Spectrum Disorder

    Science.gov (United States)

    Smith, Isabel M.; Koegel, Robert L.; Koegel, Lynn K.; Openden, Daniel A.; Fossum, Kristin L.; Bryson, Susan E.

    2010-01-01

    The Nova Scotia early intensive behavior intervention model--NS EIBI (Bryson et al., 2007) for children with autistic spectrum disorders was designed to be feasible and sustainable in community settings. It combines parent training and naturalistic one-to-one behavior intervention employing Pivotal Response Treatment--PRT (R. Koegel & Koegel,…

  11. "It Was Fine, if You Wanted to Leave": Educational Ambivalence in a Nova Scotian Coastal Community, 1963-1998

    Science.gov (United States)

    Corbett, Michael

    2004-01-01

    This article reports on a study of schooling in southwest Nova Scotia. Using Bourdieu's concepts of cultural capital and habitus, I analyze rural men's relationships involving identity, work, place, and schooling to explain continuing high male dropout rates and local traditions of ambivalence and resistance to schooling. I conclude that the…

  12. Learning To Leave: The Irony of Schooling in a Coastal Community...Some Preliminary Findings.

    Science.gov (United States)

    Corbett, Mike

    A study examined the role of education in outmigration from the rural coastal community of Digby Neck, Nova Scotia. Data gathered on 756 Grade 6 students who left Digby Neck Consolidated School between 1957 and 1992 were supplemented by in-depth interviews with 36 of those former students, 12 area educators, and community members. Findings…

  13. Enhanced Compressible Fluids Investigation

    Science.gov (United States)

    1983-04-01

    tetramethyldisiloxane and 1,1,3,3-Tetrakis (3,3,3-trifluoropropyl) dimethyldisiloxane, were synthesized by Silar Laboratories (Scotia, New York). If these showed...hypothesis, hexakis(trimethylsiloxy)disiloxane was synthesized by Silar Laboratories. The structure of the compound as inferred by its method of

  14. Georges Bank review studies list

    International Nuclear Information System (INIS)

    1999-01-01

    Federal and provincial legislation placed a moratorium on petroleum exploration and drilling on Georges Bank off southwestern Nova Scotia in 1988. Since that time, a public review was conducted to determine the environmental and socio-economic impacts of petroleum exploration on the area. Several consultant groups have been involved and prepared reports for the consideration of the Minister of Natural Resources Canada and the Minister for the Nova Scotia Department of Natural Resources. One of the consultant groups, CEF Consultants Ltd. of Halifax, Nova Scotia conducted a study which resulted in a series of papers on energy and the offshore, dealing with : (1) hydrocarbon resources, (2) exploring for offshore oil and gas, (3) offshore production, storage and transportation, (4) offshore regulation, (5) the energy context, (6) (study not available), (7) the global environmental implications of new hydrocarbon developments, and (8) communities and change. Other studies were conducted by other groups of consultants involving winds, larvae, ecosystems, an economic profile, and a historical overview of offshore and and gas development. The Ministers of Natural Resources Canada and Nova Scotia Department of Natural Resources are required to make a decision regarding the public review and moratorium by January 1, 2000

  15. Amateurs Out to Change the World: A Retrospective on Community Development.

    Science.gov (United States)

    Welton, Michael R.

    1995-01-01

    Presents a history of four phases of Canadian adult education: (1) agrarian radicalism, 1910-1945; (2) women's organizations and community development sites; (3) adult education and the crisis of democracy, 1929-1945; and (4) community building in Nova Scotia, 1954-1957. (SK)

  16. Professional Identity: A Qualitative Inquiry of Experienced Counsellors

    Science.gov (United States)

    Alves, Sara; Gazzola, Nicola

    2011-01-01

    There are many recent changes to the practice of counselling and psychotherapy in Canada. Newly established statutory regulation of psychotherapy in Ontario and Quebec, and new legislation in the province of Nova Scotia protecting the title "counselling therapist," are examples of an emerging trend in Canada that seeks to clearly define…

  17. Arctic Carbon Sinks: Present and Future.

    Science.gov (United States)

    1989-12-01

    R. Ruedy, and R. Rohan, Antarctic Salps II, J. Lerner, Climate sensitivity: Trophodynamics in the Scotia Sea and Analysis of feedback mechanisms, in...Over a longer travel distance of -1500km for water parcels observed in the 6-7 and 14 November 1976 sections across Yucatan and Florida Straits (Fig

  18. Deep Panuke offshore gas development comprehensive study report : Executive summary

    International Nuclear Information System (INIS)

    2002-10-01

    A project was proposed by EnCana Corporation (EnCana) for the development of the Deep Panuke Offshore Gas Development Project. Located offshore the Scotian Shelf, approximately 175 kilometres southeast of Goldboro, Nova Scotia and 250 kilometres southeast of Halifax, the development of this natural gas reservoir would allow EnCana to derive economic benefit from licences issued under the Canada-Nova Scotia Offshore Petroleum Resources Accord Implementation Act and the Canada-Nova Scotia Offshore Petroleum Resources Accord Implementation (Nova Scotia) Act. The Canadian Environmental Assessment Act required that a comprehensive study report be prepared, and the results were presented in this document. Consisting of three bottom-founded platforms in a water depth of approximately 40 metres, the wellhead platform would be used for dry wellheads, wellhead control system, and production manifolds. All power generation and processing equipment would be located on the production platform, and the accommodations platform would consist of the utilities, helicopter landing pad, refueling station and crew accommodations. It was determined that the Deep Panuke project was unlikely to result in adverse environmental effects. The offshore oil and gas industry in Atlantic Canada would benefit from this development as a result of the establishment of a viable facility and operation

  19. Tapping a new energy source

    International Nuclear Information System (INIS)

    Thomas, W.

    1999-01-01

    The Sable Offshore Energy Project is one of Canada's largest construction projects which is bringing a new industry to Nova Scotia. A five-party consortium comprised of Mobil Oil Canada, Shell Canada, Imperial Oil, Nova Scotia Resources and Mosbacher, has formed an enterprise called Sable Offshore Energy Inc. The consortium plans to bring natural gas to markets in Canada and the United States before the end of 1999. The Santa Fe Galaxy II is one of the world's most modern marine all-weather drilling rigs that will soon begin the drilling of wells. Once in production, the project will produce half a billion cubic feet of natural gas daily from three production platforms that will tap three separate undersea natural gas fields. The gas will then be transported 200 km to shore near Goldboro, Nova Scotia, through an undersea pipeline. There, it will be treated to remove any remaining water and to separate liquid natural gas from the gas proper. The natural gas liquids will then be carried by an onshore pipeline to a new facility at Point Tupper where they will be processed into propane, butane and condensate. There will be enough gas to meet the potential demand in Nova Scotia and New Brunswick. Large urban centres such as Halifax and Saint John will be served by secondary lines that branch off the main pipeline, but developing smaller markets will take time because the necessary infrastructure does not yet exist. The project has already created thousands of jobs in the province. 5 figs

  20. Reviving a Community's Adult Education Past: A Case Study of the Library's Role in Learning

    Science.gov (United States)

    Irving, Catherine J.

    2010-01-01

    Amidst calls for libraries to regain their socially progressive roots and connections to community, this study analyzes two interwoven cases of nonformal, community education in northeastern Nova Scotia, initiated by libraries that aimed to revive those links. Through a reading circle and a people's school, librarians used historical materials on…

  1. pdf2xml

    International Development Research Centre (IDRC) Digital Library (Canada)

    The audiovisual sector was excluded from the North American Free Trade ..... Scotia Bank – AUCC Awards for Excellence in Internationalization. ...... University terms of employment usually allow each faculty member to engage in such ...... vertical or horizontal axis, questions are raised, particularly in developing countries, ...

  2. Traumatic diaphragmatic hernia in a 5-month-old boxer dog.

    Science.gov (United States)

    Hoddinott, Katie

    2013-05-01

    A 5-month-old intact male boxer dog was presented to the Metro Animal Emergency Clinic, Dartmouth, Nova Scotia after being hit by a car. Radiography identified a diaphragmatic hernia with the stomach herniated into the thoracic cavity. Diaphragmatic herniorrhaphy and splenectomy were performed without complication. The patient returned to his regular active lifestyle.

  3. What Students Want: Elements of Job Satisfaction Expectations among Multicultural Cohorts

    Science.gov (United States)

    Brown, Dannie L.

    2015-01-01

    The purpose of this research was to assess students' expectations of future job satisfaction. Data were collected from 484 students enrolled in the BBA programme at Cape Breton University, Nova Scotia, Canada. Locke's job satisfaction theory and Hackman and Oldham's job characteristics model provided the theoretical foundation for the study.…

  4. Report on the 95th annual meeting of MSNS

    Energy Technology Data Exchange (ETDEWEB)

    1982-09-01

    Coal recovery from coal wastes, acid rain, marketing and shipping Cape Breton coal, and coal blending are discussed briefly in this account of the activities and technical sessions of the Mining Society of Nova Scotia annual meeting that was held at Ingonish Beach, June 23-26, 1982.

  5. Epilepsy and Comorbid Mental Retardation

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2007-08-01

    Full Text Available Preventable and unpreventable causes of childhood-onset epilepsy associated with mental retardation were determined in 692 patients with epilepsy onset between 1977 and 1985 in a Nova Scotia population-based cohort studied in the Department of Pediatrics, Dalhousie University, Halifax, Canada.

  6. Little Mosie from the Margaree: A Biography of Moses Michael Coady.

    Science.gov (United States)

    Welton, Michael R.

    This book examines the life of the Reverend Moses Michael Coady (1890-1959), a Roman Catholic priest who led the Antigonish Movement. During the Antigonish Movement, residents of the small maritime town of Antigonish, Nova Scotia, worked to achieve a nonviolent alternative to communism and fascism and to effect the social and economic…

  7. Men's and Women's Health Beliefs Differentially Predict Coronary Heart Disease Incidence in a Population-Based Sample

    Science.gov (United States)

    Korin, Maya Rom; Chaplin, William F.; Shaffer, Jonathan A.; Butler, Mark J.; Ojie, Mary-Jane; Davidson, Karina W.

    2013-01-01

    Objective: To examine gender differences in the association between beliefs in heart disease preventability and 10-year incidence of coronary heart disease (CHD) in a population-based sample. Methods: A total of 2,688 Noninstitutionalized Nova Scotians without prior CHD enrolled in the Nova Scotia Health Study (NSHS95) and were followed for 10…

  8. A ten-year regional assessment of sugar maple mortality

    Science.gov (United States)

    Douglas C. Allen; Andrew W. Molloy; Robert R. Cooke; Bruce A. Pendrel

    1999-01-01

    The North American Maple Project (NAMP) monitored annual sugar maple mortality from 1988 through 1997 in Maine, Massachusetts, New Brunswick/Nova Scotia, New Hampshire, New York. Ontario, Quebec, Vermont, and Wisconsin. Annual mortality in Minnesota, Ohio and Pennsylvania was evaluated for 1992 through 1997. When data from the dominant/codominant and intermediate/...

  9. "Deluded and Ruined": Diana Bastian--Enslaved African Canadian Teenager and White Male Privilege

    Science.gov (United States)

    Cooper, Afua

    2017-01-01

    This essay explores the vulnerability of enslaved African Canadian Black women by examining the death of Diana Bastian, an enslaved Black teenager who in 1792 was raped by George More, a member of the Governing Council of Cape Breton, Nova Scotia. Though Bastian begged for assistance during the resultant pregnancy, More denied her such aid and…

  10. Women Managing/Managing Women: The Marginalization of Female Leadership in Rural School Settings.

    Science.gov (United States)

    Sherman, Ann

    2000-01-01

    Examines 21 female administrators' accounts of their experience in a rural Nova Scotia school district. Presents preliminary findings of these women's own responses, resistances, and initiatives while attempting to legitimize and implement their preferred leadership styles, which stressed relationships, instructional leadership, communication, and…

  11. Definition of Quality of Education: The Halifax Plan.

    Science.gov (United States)

    Doehler, Murray E.; Perry, Karl W.

    1987-01-01

    Professional personnel and building maintenance were studied by the Halifax School District Board (Nova Scotia) to examine economy and efficiency and to determine quality education, using the value-for-money concept. This process can be utilized by any board to assist in identifying areas needing analysis, but program effectiveness should also be…

  12. The Role of Prenatal, Obstetric and Neonatal Factors in the Development of Autism

    Science.gov (United States)

    Dodds, Linda; Fell, Deshayne B.; Shea, Sarah; Armson, B. Anthony; Allen, Alexander C.; Bryson, Susan

    2011-01-01

    We conducted a linked database cohort study of infants born between 1990 and 2002 in Nova Scotia, Canada. Diagnoses of autism were identified from administrative databases with relevant diagnostic information to 2005. A factor representing genetic susceptibility was defined as having an affected sibling or a mother with a history of a psychiatric…

  13. First Southeast U.S. records for Lacconotus punctatus Leconte (Coleoptera: Mycteridae), an early seasonal canopy specialist?

    Science.gov (United States)

    Michael Ulyshen; Scott Horn; James Hanula

    2010-01-01

    A recent project carried out within the Oconee River watershed in northeastern Georgia produced six specimens of Lacconotus punctatus LeConte, a species formerly known only from the northeastern United States (New Hampshire, Ohio, Pennsylvania, Michigan) and Canada (Ontario, Québec, Nova Scotia) ( Majka and Selig 2006, and references therein). Georgia represents a new...

  14. Pre-injection of hyaluronic acid does not affect the systemic effects of intra-articular depot betamethasone injection at the knee joint.

    Science.gov (United States)

    Habib, George; Khatib, Muhamad; Sakas, Fahed; Artul, Suheil; Jabaly-Habib, Haneen

    2017-01-01

    Intra-articular injection (IAI) of both hyaluronic acid (HA) and depot-steroid preparations had the advantage of quick and prolonged favorable effects on pain relief among patients with symptomatic osteoarthritis of the knee (OAK). The effect of IAI of HA on the systemic effects of the intra-articular steroids had not been investigated. Non-selected patients attending the rheumatology clinic with symptomatic OAK who failed NSAIDS and physical therapy were offered an IAI of HA at the knee joint followed 20 min later by an IAI of 1 ml of Celestone Chronodose at the same joint (group 1). Morning serum levels of cortisol were obtained just prior to the IAI and 1, 2 and 8 days later. Demographic, clinical, and laboratory parameters were obtained also from all the patients. Age- and sex-matched group of patients from the same clinic were recruited as a control group (group 2). Mean baseline serum cortisol levels in group 1 was 381 ± 154 mmol/l vs. 376 ± 119 in group 2 (p = 0.954). Morning serum cortisol levels at day 1 and day 2 were 24 ± 6 and 22 ± 6 mmol/l, respectively, in group 1 patients vs. 27 ± 5.8 (p = 0.214) and 25 ± 5.6 mmol/l (p = 0.200), respectively, in group 2. These levels were significantly lower than baseline levels in each group. Morning serum cortisol levels at day 8 in group 1 and group 2 were 349 ± 128 and 314 ± 99 mmol/l, respectively (p = 0.419). Pre-injection of HA at the knee joint did not affect the systemic effect on the hypothalamic-pituitary-adrenal axis of IAI of Celestone Chronodose.

  15. Monte Carlo simulation of radiation transport and dose deposition from locally released gold nanoparticles labeled with 111In, 177Lu or 90Y incorporated into tissue implantable depots

    Science.gov (United States)

    Lai, Priscilla; Cai, Zhongli; Pignol, Jean-Philippe; Lechtman, Eli; Mashouf, Shahram; Lu, Yijie; Winnik, Mitchell A.; Jaffray, David A.; Reilly, Raymond M.

    2017-11-01

    Permanent seed implantation (PSI) brachytherapy is a highly conformal form of radiation therapy but is challenged with dose inhomogeneity due to its utilization of low energy radiation sources. Gold nanoparticles (AuNP) conjugated with electron emitting radionuclides have recently been developed as a novel form of brachytherapy and can aid in homogenizing dose through physical distribution of radiolabeled AuNP when injected intratumorally (IT) in suspension. However, the distribution is unpredictable and precise placement of many injections would be difficult. Previously, we reported the design of a nanoparticle depot (NPD) that can be implanted using PSI techniques and which facilitates controlled release of AuNP. We report here the 3D dose distribution resulting from a NPD incorporating AuNP labeled with electron emitters (90Y, 177Lu, 111In) of different energies using Monte Carlo based voxel level dosimetry. The MCNP5 Monte Carlo radiation transport code was used to assess differences in dose distribution from simulated NPD and conventional brachytherapy sources, positioned in breast tissue simulating material. We further compare these dose distributions in mice bearing subcutaneous human breast cancer xenografts implanted with 177Lu-AuNP NPD, or injected IT with 177Lu-AuNP in suspension. The radioactivity distributions were derived from registered SPECT/CT images and time-dependent dose was estimated. Results demonstrated that the dose distribution from NPD reduced the maximum dose 3-fold when compared to conventional seeds. For simulated NPD, as well as NPD implanted in vivo, 90Y delivered the most homogeneous dose distribution. The tumor radioactivity in mice IT injected with 177Lu-AuNP redistributed while radioactivity in the NPD remained confined to the implant site. The dose distribution from radiolabeled AuNP NPD were predictable and concentric in contrast to IT injected radiolabeled AuNP, which provided irregular and temporally variant dose distributions

  16. 1998 annual report

    International Nuclear Information System (INIS)

    1999-05-01

    Operational and financial information from Nova Scotia Power Inc. for 1998 was presented. The utility is the major supplier of electricity in Nova Scotia and serves over 430,000 residential, commercial and industrial customers. Assets of the business total 2.8 billion. Nova Scotia Power provides 97 per cent of the electric power generation, 99 per cent of transmission and 95 per cent of the distribution of electric power in the province. At present, Nova Scotia Power uses mostly coal and oil for power generation, but these will be gradually displaced as natural gas from the Sable Offshore Energy Project comes on stream. The availability of natural gas for power generation is assured through the Utility's 12.5 per cent stake in the Maritimes and Northeast natural gas pipeline. In 1998 the record warm, dry weather reduced residential and commercial revenues and increased fuel costs, which contributed to lower earnings. The Utility signed a 10-year contract with Shell Canada Limited to purchase 62 million cubic feet of gas per day, or 11 per cent of the expected production of Sable Offshore Energy Inc. As part of its strategy to capitalize on Sable gas, the Utility decided to re-fit its Tufts Cove generating station to burn Sable gas or oil and it also decided not to pursue the rights to distribute natural gas in Nova Scotia. Over half of the company's thermal generating plants implemented successful advance date changes with systems already operating in Year 2000 mode. Ratings of system reliability significantly improved during the year and safety performance was the best ever. The Utility was reorganized into a holding company structure effective January 1, 1999, after receiving shareholder and legislative approvals. tabs., figs

  17. Impact of gas on utilities - competitive energy options

    International Nuclear Information System (INIS)

    Coolican, M.

    1997-01-01

    The initiatives taken by Nova Scotia Power to have natural gas as a generating fuel was discussed. Nova Scotia Power customers have indicated to the Utility that along with reduced energy costs, they want choices, better services and innovative products. It was noted that coal is currently Nova Scotia Power's principal fuel, but the utility is working with the Cape Breton Development Corporation, their supplier, to bring the cost of coal down. The utility is also exploring the potential of coal bed methane in Pictou and Cumberland counties of Nova Scotia. However, the most promising competitive energy option for their customers is Sable Offshore natural gas. To bring natural gas as the generating fuel for electricity, the Utility is taking steps to convert its Tufts Cove Thermal Generating Station to natural gas and to pipe natural gas to the Trenton Generating Station by November 1999. Bringing natural gas to these two stations would establish a critical base level of demand for natural gas in the Halifax and New Glasgow-Trenton area. One of the important ingredients of this plan is the cost of piping the gas to market. It was suggested that the 'postage stamp' tolling system (i.e. one price for the gas delivered anywhere along the pipeline) favored by some, would not give Nova Scotians the economic advantages that they deserve. For this reason, Nova Scotia Power favours the 'point to point' tolling system, a system that is considered fair and efficient, and the one that has a better chance of producing competitive energy prices

  18. Measurements and Clinical Findings on Thorotrast Deposits in the Kidney; Mesures et Observations Cliniques Faites sur des Depots de Thorotrast dans le Rein; 0418 0417 041c 0414 ; Determinaciones y Datos Clinicos Relativos a los Depositos Renales de Torotrasto

    Energy Technology Data Exchange (ETDEWEB)

    Oberhausen, E.; Muth, H.; Grillmaier, R. [Institut Fuer Biophysik der Universitaet des Saarlandes, Homburg (Saar), Federal Republic of Germany (Germany)

    1964-11-15

    There exists a relatively large number of publications about Thorotrast deposits in, the reticulo-endothelial system and the clinical findings caused by these deposits. But only, a few cases with Thorotrast deposits in the kidney have been reported. Despite this it is to be expected that there are numerous patients with Thorotrast deposits in the kidneys, because Thorotrast has been used very often as a contrast medium in retrograde pyelographies. Under normal conditions all the Thorotrast should have been swept out of the kidney with, the urine. But if it was applied under higher pressure or if there existed an infection of the Sidney at the same time, part of the Thorotrast might have, been deposited in the tissues. It is possible that a higher number of these deposits is not recognized in X-ray pictures because they look very similar to calcium deposits in the kidney and some experience is needed to distinguish calcium from Thorotrast deposits. In co-operation with our urological clinic we have found seven cases in the last years. When there was only a deposit in one kidney, which was the case in six patients, the or organ was taken out. Histological examination showed five carcinomas and in one kidney there were already enormous degenerative changes. According to our observations the time necessary for the development of carcinoma is between 20 and 25 yr. In two cases we have been able to measure the patient in the whole-body counter and to measure the radioactive substances in the urine and the thoron in the breath. All these, measurements have been done before and after nephrectomy. The gamma-rays of the isolated organ itself have also been measured. From these measurements an evaluation of radiation dose is possible. (author) [French] Il existe un nombre relativement grand de publications sur les depots de thorotrast dans le systeme reticuloendothelial et les phenomenes cliniques provoques par ces depots. Par contre on n'a signale que peu de cas de depots de

  19. Geochemical evidence of groundwater flow paths and the fate and transport of constituents of concern in the alluvial aquifer at Fort Wingate Depot Activity, New Mexico, 2009

    Science.gov (United States)

    Robertson, Andrew J.; Henry, David W.; Langman, Jeffery B.

    2013-01-01

    As part of an environmental investigation at Fort Wingate Depot Activity, New Mexico, the U.S. Geological Survey, in cooperation with the U.S. Army Corps of Engineers, interpreted aqueous geochemical concentrations to better understand the groundwater flow paths and the fate and transport of constituents of concern in the alluvial aquifer underlying the study area. The fine-grained nature of the alluvial matrix creates a highly heterogeneous environment, which adds to the difficulty of characterizing the flow of groundwater and the fate of aqueous constituents of concern. The analysis of the groundwater geochemical data collected in October 2009 provides evidence that is used to identify four groundwater flow paths and their extent in the aquifer and indicates the dominant attenuation processes for the constituents of concern. The extent and interaction of groundwater flow paths were delineated by the major ion concentrations and their relations to each other. Four areas of groundwater recharge to the study area were identified based on groundwater elevations, hydrogeologic characteristics, and geochemical and isotopic evidence. One source of recharge enters the study area from the saturated alluvial deposits underlying the South Fork of the Puerco River to the north of the study area. A second source of recharge is shown to originate from a leaky cistern containing production water from the San Andres-Glorieta aquifer. The other two sources of recharge are shown to enter the study area from the south: one from an arroyo valley draining an area to the south and one from hill-front recharge that passes under the reported release of perchlorate and explosive constituents. The spatial extent and interaction of groundwater originating from these various sources along identified flow paths affect the persistence and attenuation of constituents of concern. It was determined that groundwater originating in the area of a former explosives’ wash-out operation and an

  20. The DHEA-sulfate depot following P450c17 inhibition supports the case for AKR1C3 inhibition in high risk localized and advanced castration resistant prostate cancer.

    Science.gov (United States)

    Tamae, Daniel; Mostaghel, Elahe; Montgomery, Bruce; Nelson, Peter S; Balk, Steven P; Kantoff, Philip W; Taplin, Mary-Ellen; Penning, Trevor M

    2015-06-05

    Prostate cancer is the second leading cause of cancer death in the United States. Treatment of localized high-risk disease and de novo metastatic disease frequently leads to relapse. These metastatic castration resistant prostate cancers (mCRPC) claim a high mortality rate, despite the extended survival afforded by the growing armamentarium of androgen deprivation, radiation and immunotherapies. Here, we review two studies of neoadjuvant treatment of high-risk localized prostate cancer prior to prostatectomy, the total androgen pathway suppression (TAPS) trial and the neoadjuvant abiraterone acetate (AA) trial. These two trials assessed the efficacy of the non-specific P450c17 inhibitor, ketoconazole and the specific P450c17 inhibitor, AA, to inhibit tissue and serum androgen levels. Furthermore, a novel and validated stable isotope dilution liquid chromatography electrospray ionization selected reaction monitoring mass spectrometry assay was used to accurately quantify adrenal and gonadal androgens in circulation during the course of these trials. The adrenal androgens, Δ(4)-androstene-3,17-dione, dehydroepiandrosterone and dehydroepiandrosterone sulfate were significantly reduced in the patients receiving ketoconazole or AA compared to those who did not. However, in both trials, a significant amount of DHEA-S (∼20 μg/dL) persists and thus may serve as a depot for intratumoral conversion to the potent androgen receptor ligands, testosterone (T) and 5α-dihydrotestosterone (DHT). The final step in conversion of Δ(4)-androstene-3,17-dione and 5α-androstanedione to T and DHT, respectively, is catalyzed by AKR1C3. We therefore present the case that in the context of the DHEA-S depot, P450c17 and AKR1C3 inhibition may be an effective combinatorial treatment strategy. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.