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Sample records for schulz earl creech

  1. The Earl Lee Street Art Campaign

    Science.gov (United States)

    Bubba

    2013-01-01

    This article describes a catchy phrase with more to its meaning than first view. A slogan "All the girls love Earl Lee," appears in street art around the world. Earl Lee is a lovable, handsome man who owns the fictitious Earl Lube industries. Originally intended to bring a smile to people's faces at a time when there wasn't much to smile…

  2. Minu nimi on Earl / Kaido Soorsk

    Index Scriptorium Estoniae

    Soorsk, Kaido, 1973-

    2008-01-01

    Ameerika autodisainerist Harley Earl'ist (1893-1969) ja tema tähtsamatest töödest: Buick Y-Job (1938), LeSabre (1951), Chevrolet Corvette (1953). Harley Earl juhtis General Motorsi Art and Color Section'it, mis 1937. a. nimetati ümber Style Section'iks

  3. NREL's Earl Christensen Honored with Two Awards from National Biodiesel

    Science.gov (United States)

    Board | News | NREL NREL's Earl Christensen Honored with Two Awards from National Biodiesel Board NREL's Earl Christensen Honored with Two Awards from National Biodiesel Board February 16, 2018 Fuel stability research advances innovation and bolsters industry confidence in biodiesel. Scott

  4. Nekroloog turundusele / Mark Earls ; interv. Margo Kokerov

    Index Scriptorium Estoniae

    Earls, Mark

    2003-01-01

    Turunduskommunikatsioonifirma Ogilvy & Mather suunajuht Mark Earls leiab, et kuna turg on üle ujutatud võrdselt heade toodetega ja tarbija teab, et tegelikult pole oluline, millise toote ta valib, muutub turundusrevolutsiooni keskne idee - tarbijavajaduste kindlakstegemine ja rahuldamine - tähtsusetuks.

  5. Digital PET compliance to EARL accreditation specifications

    NARCIS (Netherlands)

    Koopman, Daniëlle; Groot Koerkamp, Maureen; Jager, Pieter L.; Arkies, Hester; Knollema, Siert; Slump, Cornelis H.; Sanches, Pedro G.; van Dalen, Jorn A.

    2017-01-01

    Background: Our aim was to evaluate if a recently introduced TOF PET system with digital photon counting technology (Philips Healthcare), potentially providing an improved image quality over analogue systems, can fulfil EANM research Ltd (EARL) accreditation specifications for tumour imaging with

  6. Ver Schulz: metamorfoses de um Projeto Artístico

    OpenAIRE

    Dantas, élida Mara Alves

    2014-01-01

    Este estudo se configura como um mergulho no universo do multifacetado artista polonês Bruno Schulz (1892-1942), desenhista gráfico, pintor, ilustrador, poeta, crítico literário e escritor do entreguerras, nascido na cidade de Drohobycz e morto em uma de suas ruas durante a Segunda Guerra Mundial. Reconhecido mundialmente, embora pouco conhecido no Brasil, Schulz se destaca pela sua versatilidade, pelas peculiaridades de sua biografia, e, sobretudo, pela sua curta, mas significante produção l...

  7. Earl Busby Hunt (1933-2016).

    Science.gov (United States)

    Greenwald, Anthony G

    2017-01-01

    Presents an obituary for Earl Busby Hunt-known to family, friends, and colleagues as Buz-who died at home in Bellevue, Washington, on April 12, 2016. Buz specialized in artificial intelligence (AI) and had a main focus in cognitive psychology. In fact he was editor of Cognitive Psychology from 1974-1987. Buz's honors include the Lifetime Achievement Award from the International Society for Intelligence Research (2009) and the Cattell Award from the Association for Psychological Science (2011) for lifetime contributions. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  8. Nachruf für Hartmut Schulz : (13. Juli 1939 - 19. Juni 2003)

    OpenAIRE

    Klee, Rainer; Buttler, Karl Peter; Hodvina, Sylvain

    2003-01-01

    Am 19. Juni 2003 verstarb Hartmut Schulz, einer der Gründer der BVNH. Leben und Werk werden in einem durch Rainer Klee verfassten Nachruf gewürdigt. Es folgt eine von Karl Peter Buttler und Sylvain Hodvina erstellte Liste der Veröffentlichungen von Hartmut Schulz.

  9. Micelle-derived catalysts for extended Schulz-Flory

    Energy Technology Data Exchange (ETDEWEB)

    Abrevaya, H.

    1986-01-01

    The objective of this program is to develop a synthesis gas conversion catalyst with higher selectivity to liquid fuels, while maintaining catalytic activity and stability at least equivalent relative to state-of-the-art precipitated iron catalysts. During this quarter, the emphasis in the program has been the investigation of the hydrocarbon cutoff hypothesis with supported ruthenium catalysts. An alumina-supported catalyst with smaller than 20[Angstrom] ruthenium particles was tested under conditions of maximal water gas shift activity. During this test more than 90% of the water made in the Fischer-Tropsch synthesis reaction was converted to H[sub 2]. However, the extent of ruthenium metal agglomeration was not reduced. Accordingly, it was not possible to conclude whether hydrocarbon cutoff occurs with smaller than 20[Angstrom] ruthenium particles on [gamma]-alumina. A ruthenium catalyst prepared on Y-type zeolite had 20[Angstrom] or smaller ruthenium particles according to STEM examination and a 15[Angstrom] average ruthenium metal particle size according to EXAFS examination. The ruthenium metal particle size was stable during the test with this catalyst. The hydrocarbon product distribution was Anderson-Schulz-Flory with no cutoff up to a carbon number of 160. A well-dispersed titania-supported ruthenium catalyst is going to be evaluated during the next quarter in order to determine whether hydrocarbon cutoff occurs.

  10. Obituary: Earle B. Mayfield (1923-2007)

    Science.gov (United States)

    Chapman, Gary

    2011-12-01

    Earle B. Mayfield passed away peacefully in his sleep 28 May 2007 in Los Osos, near San Luis Obispo. He retired there to grow orchids, make wine and teach part-time at California Polytechnic University, San Luis Obispo (Cal Poly SLO). He was born in Oklahoma City in 1923. After his discharge from the Coast Guard he went to UCLA where he graduated in physics in 1950. He married Peggy Masterson in 1952 after they met while they both worked at the China Lake Test Station. He obtained a Ph.D. in physics in 1959 from the University of Utah. He is survived by his wife, seven children and 14 grandchildren. In 1960 Mayfield joined The Aerospace Corporation where he became a strong proponent of expanding the Corporation's activities in solar research. In 1966, with Mayfield's support, observations of supergranulation were obtained from Thule, Greenland, that spanned nearly 62 hours of continuous coverage: the longest continuous solar observations at that time. He was instrumental in the effort to design and construct an advanced 24-inch aperture vacuum solar telescope. The resulting diffraction limited image had an un-vignetted field-of-view of about 0.8 Re. An auxiliary 11-inch vacuum telescope was available for full-disk observations. Both telescopes were F/20 with reflecting surfaces having proprietary overcoated silver. At the Coude focus was a vacuum spectroheliograph. It was determined that a peninsula jutting out into the Upper Van Norman Reservoir provided superior seeing conditions that was the site of an U.S. Air Force Air Weather Service station. This became the San Fernando Observatory, which was dedicated in February 1969 just before an ad hoc meeting of the Solar Physics Division in Pasadena. Mayfield was its first director. In 1971, under Mayfield's direction, Aerospace developed the first digital video magnetograph supported by a NASA grant. This provided real-time magnetograms of solar active regions. In 1973, James Underwood came to Aerospace and the

  11. Masochisms. Mythologizing as an Aesthetics of Crisis in the Work of Bruno Schulz

    Directory of Open Access Journals (Sweden)

    Janis Augsburger

    2011-01-01

    Full Text Available The study Masochisms. Mythologizing as an Aesthetics of Crisis in the Work of Bruno Schulz, parts of which have been translated below, presents the thesis that in the work of B. Schulz the phenomenon of mythologizing is connected with masochism – a concept conceived of as a historical, cultural and aesthetic interpretative category. The combination of the two phenomena makes it possible to notice some relationships between Schulz’s literary and graphic works which have not been recognized yet. The author discusses some psychoanalytical, sociological, historical and philosophical notions of masochism applicable to a literary text. She tries to describe the “masochistic aesthetics” appearing in Schulz’s short stories (on the narrative level: lack of motion, suspense, tension and in his graphics (theatricalization, lack of eye contact between the figures and shows how this aesthetics integrates the prose of Schulz, his Idolatrous Book and his illustrations for the short story The Book.

  12. Passings to note: Paul Michael Packman, MD; S. Charles Schulz, MD.

    Science.gov (United States)

    Black, Donald W

    2018-02-01

    One of the keys to the success of Annals of Clinical Psychiatry has always been the tireless efforts of our dedicated Editorial Board. We recently lost 2 longtime Editorial Board members, Drs. Paul Michael Packman and S. Charles Schulz. Both will be greatly missed.

  13. December Variations (on a Theme by Earle Brown)

    OpenAIRE

    2014-01-01

    Earle Brown’s December 1952 is a score characterised by the use of 31 abstract graphical elements. Brown later re-imagined it as a Calderesque orrery in which “elements would actually physically be moving in front of the pianist” [1]. Although there are many more recent examples of graphic, open and animated scores, for the purposes of this practice-led research the simplicity and grace of Brown’s score makes it a pragmatic choice as it is significantly easier to follow the “translations” bei...

  14. Raudtee uus tegevjuht lubab pikki ronge ja rohkem tonne / Earl Currie ; interv. Tuuli Koch

    Index Scriptorium Estoniae

    Currie, Earl

    2001-01-01

    Eesti Raudtee juhatuse esimees Earl Currie raudtee eelmise juhtkonna tegutsemisest, uue juhtkonna seisukohast läbirääkimistel ametiühingutega muutustest ER-i juhtimises, olulisematest investeeringutest jm. Earl Currie eluloost. Vt. samas "Rask näeb Savisaare avalduses kommunismi"

  15. Colloidal Stability in Asymmetric Electrolytes: Modifications of the Schulze-Hardy Rule.

    Science.gov (United States)

    Trefalt, Gregor; Szilagyi, Istvan; Téllez, Gabriel; Borkovec, Michal

    2017-02-21

    The Schulze-Hardy rule suggests a strong dependence of the critical coagulation concentration (CCC) on the ionic valence. This rule is addressed theoretically and confronted with recent experimental results. The commonly presented derivation of this rule assumes symmetric electrolytes and highly charged particles. Both assumptions are incorrect. Symmetric electrolytes containing multivalent ions are hardly soluble, and experiments are normally carried out with the well-soluble salts of asymmetric electrolytes containing monovalent and multivalent ions. In this situation, however, the behavior is completely different whether the multivalent ions represent the counterions or co-ions. When these ions represent the counterions, meaning that the multivalent ions have the opposite sign than the charge of the particle, they adsorb strongly to the particles. Thereby, they progressively reduce the magnitude of the surface charge with increasing valence. In fact, this dependence of the charge density on the counterion valence is mainly responsible for the decrease of the CCC with the valence. In the co-ion case, where the multivalent ions have the same sign as the charge of the particle, the multivalent ions are repelled from the particles, and the surfaces remain highly charged. In this case, the inverse Schulze-Hardy rule normally applies, whereby the CCC varies inversely proportional to the co-ion valence.

  16. “Just an American Boy”. The Political Songwriting of Steve Earle “Just an American Boy” : la chanson politique de Steve Earle

    Directory of Open Access Journals (Sweden)

    Richard Jobes

    2009-11-01

    Full Text Available Un an après les attentats du 11 septembre, Steve Earle, dans son album Jerusalem, a été le premier à faire entendre dans le monde du rock une voix discordante sur l’Amérique contemporaine. Honni par la droite, qui s’est inscrite en faux contre une prise de position qu’elle considère antipatriotique, mais salué par la gauche américaine, Jerusalem s’est retrouvé au centre du débat politique actuel. L’objet de cet article sera de montrer comment s’inscrit ce disque dans le contexte des États-Unis d’aujourd’hui ainsi que sa place dans l’œuvre engagée de Steve Earle.

  17. The impact of Saharan Dust on the genesis and evolution of Hurricane Earl (2010)

    Science.gov (United States)

    Pan, B.; Wang, Y.; Hsieh, J. S.; Lin, Y.; Hu, J.; Zhang, R.

    2017-12-01

    Dust, one of the most abundant natural aerosols, can exert substantial radiative and microphysical effects on the regional climate and has potential impacts on the genesis and intensification of tropical cyclones (TCs). A Weather Research and Forecasting Model and the Regional Oceanic Modeling System coupled model (WRF-ROMS) is used to simulate the evolution of Hurricane Earl (2010), of which Earl was interfered by Saharan dust at the TC genesis stage. A new dust module has been implemented to the TAMU two-moment microphysics scheme in the WRF model. It accounts for both dust as Cloud Condensation Nuclei (CCN) and Ice Nuclei (IN). The hurricane track, intensity and precipitation have been compared to the best track data and TRMM precipitation, respectively. The influences of Saharan dust on Hurricane Earl are investigated with dust-CCN, dust-IN, and dust-free scenarios. The analysis shows that Saharan dust changes the latent heat and moisture distribution, invigorates the convections in the hurricane's eyewall, and suppresses the development of Earl. This finding addresses the importance of accounting dust microphysics effect on hurricane predictions.

  18. O crepúsculo da ética imperial habsburga em Bruno Schulz e Joseph Roth The twilight of the Habsburg imperial ethics in Bruno Schulz and Joseph Roth

    Directory of Open Access Journals (Sweden)

    Luis S. Krausz

    2007-05-01

    Full Text Available Os escritores Bruno Schulz e Joseph Roth entraram para a história da literatura, respectivamente, como representantes da literatura polonesa e austríaca, como se pertencessem a mundos diversos. Entretanto ambos compartilharam de uma memória comum, que era a vida nas províncias orientais do Império Austro-Húngaro, nas cidades de Drohobycz e Brody, hoje pertencentes à Ucrânia. As obras de ficção de Schulz e de Roth fazem referência ao universo austro-húngaro e habsburgo, um reino milenar que via a si mesmo não simplesmente como uma realidade política, mas como um império que tinha como missão trazer a seus súditos uma forma de vida considerada superior do ponto de vista espiritual, ético e moral. A idéia do Sacro Império Romano Germânico, que se considerava portador de uma mensagem humana, subsistiu, até o século 20, no longo reinado do Kaiser Francisco José e neste sentido a 1ª Guerra Mundial significa não simplesmente o desmembramento político do Império Austro-Húngaro em seus diferentes componentes, mas também a falência de uma idéia de Estado que transcendia à esfera do meramente político para tornar-se um lar espiritual e cultural para seus súditos. O mundo que sobreveio à 1ª Guerra Mundial é marcado pelas tendências fáustico-titânicas de um individualismo materialista, que devota todas suas energias à produção e à acumulação de capital, e é sobre este novo mundo que Schulz e Roth olham em suas obras, sempre do ponto de vista de um universo anterior, marcado pela nostalgia de um exílio irreversível. Palavras-chave: Nostalgia. Exílio. Império Habsburgo. Joseph Roth. Bruno Schulz. Bruno Schulz and Joseph Roth figure in the history of literature as Representatives of Polish and Austrian literature, respectively, as if they were part of different worlds. However, both share a common memory: the life in the eastern provinces of the Austrian-Hungarian Empire, in the cities of Drohobycz

  19. Destabilization of Titania Nanosheet Suspensions by Inorganic Salts: Hofmeister Series and Schulze-Hardy Rule.

    Science.gov (United States)

    Rouster, Paul; Pavlovic, Marko; Szilagyi, Istvan

    2017-07-13

    Ion specific effects on colloidal stability of titania nanosheets (TNS) were investigated in aqueous suspensions. The charge of the particles was varied by the pH of the solutions, therefore, the influence of mono- and multivalent anions on the charging and aggregation behavior could be studied when they were present either as counter or co-ions in the systems. The aggregation processes in the presence of inorganic salts were mainly driven by interparticle forces of electrostatic origin, however, chemical interactions between more complex ions and the surface led to additional attractive forces. The adsorption of anions significantly changed the surface charge properties and hence, the resistance of the TNS against salt-induced aggregation. On the basis of their ability in destabilization of the dispersions, the monovalent ions could be ordered according to the Hofmeister series in acidic solutions, where they act as counterions. However, the behavior of the biphosphate anion was atypical and its adsorption induced charge reversal of the particles. The multivalent anions destabilized the oppositely charged TNS more effectively and the aggregation processes followed the Schulze-Hardy rule. Only weak or negligible interactions were observed between the anions and the particles in alkaline suspensions, where the TNS possessed negative charge.

  20. Recognizing Genius loci in Designing Children’s Spaces, Due to the Phenomenological Ideas of Norberg-Schulz

    Directory of Open Access Journals (Sweden)

    R. Nikravesh

    2015-02-01

    Full Text Available Christian Norberg- Schulz explained his ideas about the phenomenology of architecture, indebted to Martin Heidegger’s opinionsand believed that one of the main strategies for identification of the place is creating meaningful environments. Schulz can be considered as one of theorists who created new ideas in architecture after Gideon and believed that considering to other scientific fields is necessary to achieve the true nature of architecture. In fact the phenomenological approach can be understood as an interdisciplinary species that explain about existence and cognition in other fields like designing different spaces. Accordingly emphasizing on interdisciplinary trends and studies can help to identify and understand the multiple issues and by studying the different approaches, the scientific expansion of the problem’s aspects will be possible. This article with an Interdisciplinary and phenomenological point of view and due to the main ideas of Norberg- Schulz, analyses the concept of place and space and also the importance of concerning about children’s spaces. So at first a brief knowledge about the book of Norberg-Schulz in phenomenological approach will be achieved and by studying the opinions of other theorists, some results about the importance of considering the concept of genius loci in architectural spaces will be achieved. In this document, by using the descriptive- analytical method and by means of data collection, including studies, library and documentation, the relating concepts and strategies of improving the quality of children’s spaces, is analyzed. According to this article, It could be said that meanings, culture and history of a place, include identifying factors that cause creating memories and a sense of belonging to the place for individuals and thus the formation of their personality in childhood. So one of the main tasks of modern architects is creating a sense of space in children’s spaces and reminding

  1. Effects of 2010 Hurricane Earl amidst geologic evidence for greater overwash at Anegada, British Virgin Islands

    Science.gov (United States)

    Atwater, B. F.; Fuentes, Z.; Halley, R. B.; Ten Brink, U. S.; Tuttle, M. P.

    2014-03-01

    A post-hurricane survey of a Caribbean island affords comparisons with geologic evidence for greater overwash at the same place. This comparison, though of limited application to other places, helps calibrate coastal geology for assessment of earthquake and tsunami potential along the Antilles Subduction Zone. The surveyed island, Anegada, is 120 km south of the Puerto Rico Trench and is near the paths of hurricanes Donna (1960) and Earl (2010), which were at or near category 4 when at closest approach. The survey focused on Earl's geologic effects, related them to the surge from Hurricane Donna, and compared them further with erosional and depositional signs of southward overwash from the Atlantic Ocean that dates to 1200-1450 AD and to 1650-1800 AD. The main finding is that the geologic effects of these earlier events dwarf those of the recent hurricanes. Hurricane Earl's geologic effects at Anegada, observed mainly in 2011, were limited to wrack deposition along many of the island's shores and salt ponds, accretion of small washover (spillover) fans on the south shore, and the suspension and deposition of microbial material from interior salt ponds. Earl's most widespread deposit at Anegada, the microbial detritus, was abundantly juxtaposed with evidence for catastrophic overwash in prior centuries. The microbial detritus formed an extensive coating up to 2 cm thick that extended into breaches in beach-ridge plains of the island's north shore, onto playas that are underlain by a sand-and-shell sheet that extends as much as 1.5 km southward from the north shore, and among southward-strewn limestone boulders pendant to outcrops as much as 1 km inland. Earl's spillover fans also contrast with a sand-and-shell sheet, which was dated previously to 1650-1800, by being limited to the island's south shore and by extending inland a few tens of meters at most. These findings complement those reported in this issue by Michaela Spiske and Robert Halley (Spiske and Halley

  2. EANM/EARL harmonization strategies in PET quantification: from daily practice to multicentre oncological studies

    Energy Technology Data Exchange (ETDEWEB)

    Aide, Nicolas [University Hospital, Nuclear Medicine Department, Caen (France); Caen University, Inserm U1086 ANTICIPE, Caen (France); Lasnon, Charline [Caen University, Inserm U1086 ANTICIPE, Caen (France); Francois Baclesse Cancer Centre, Nuclear Medicine Department, Caen (France); Veit-Haibach, Patrick [University Hospital Zurich, Department of Nuclear Medicine and Department of Diagnostic and Interventional Radiology, Zurich (Switzerland); University Health Network, University of Toronto, Joint Department Medical Imaging, Toronto (Canada); Sera, Terez [University of Szeged, Nuclear Medicine Department, Szeged (Hungary); Sattler, Bernhard [University Hospital of Leipzig, Department of Nuclear Medicine, Leipzig (Germany); Boellaard, Ronald [University of Groningen, University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); VU University Medical Center, Department of Radiology and Nuclear Medicine, Amsterdam (Netherlands)

    2017-08-15

    Quantitative positron emission tomography/computed tomography (PET/CT) can be used as diagnostic or prognostic tools (i.e. single measurement) or for therapy monitoring (i.e. longitudinal studies) in multicentre studies. Use of quantitative parameters, such as standardized uptake values (SUVs), metabolic active tumor volumes (MATVs) or total lesion glycolysis (TLG), in a multicenter setting requires that these parameters be comparable among patients and sites, regardless of the PET/CT system used. This review describes the motivations and the methodologies for quantitative PET/CT performance harmonization with emphasis on the EANM Research Ltd. (EARL) Fluorodeoxyglucose (FDG) PET/CT accreditation program, one of the international harmonization programs aiming at using FDG PET as a quantitative imaging biomarker. In addition, future accreditation initiatives will be discussed. The validation of the EARL accreditation program to harmonize SUVs and MATVs is described in a wide range of tumor types, with focus on therapy assessment using either the European Organization for Research and Treatment of Cancer (EORTC) criteria or PET Evaluation Response Criteria in Solid Tumors (PERCIST), as well as liver-based scales such as the Deauville score. Finally, also presented in this paper are the results from a survey across 51 EARL-accredited centers reporting how the program was implemented and its impact on daily routine and in clinical trials, harmonization of new metrics such as MATV and heterogeneity features. (orig.)

  3. William Parsons, 3rd Earl of Rosse astronomy and the castle in nineteenth-century Ireland

    CERN Document Server

    Mollan, R Charles

    2015-01-01

    This is a revealing account of the family life and achievements of the Third Earl of Rosse, a hereditary peer and resident landlord at Birr Castle, County Offaly, in nineteenth-century Ireland, before, during and after the devastating famine of the 1840s. He was a remarkable engineer, who built enormous telescopes in the cloudy middle of Ireland. The book gives details, in an attractive non-technical style which requires no previous scientific knowledge, of his engineering initiatives and the astronomical results, but also reveals much more about the man and his contributions - locally in the

  4. Review of The Earl of Abergavenny. Historical Record and Wreck Excavation CD-Rom

    OpenAIRE

    David Petts

    2003-01-01

    In early February 1805 a small fleet of East Indiamen accompanied by the frigate Weymouth set sail from Portsmouth heading first for Bengal and ultimately for China. However, barely had the voyage began when, following bad weather and confusion, one of the boats, the Earl of Abergavenny, struck the Shambles bank just off Portland Bill. Although the crew managed to free it, it was so badly damaged it sank while trying to make for the safety of Weymouth. Over 250 crew and passengers drowned. Th...

  5. Je třeba číst z letu těch ptáků : o kabalistické interpretaci Bruna Schulze

    Czech Academy of Sciences Publication Activity Database

    Fottová, Magdaléna

    2017-01-01

    Roč. 10, č. 40 (2017), s. 24-29 ISSN 1803-8077 Institutional support: RVO:68378068 Keywords : Schulz, Bruno * Panas, Władysław * Jewish literature * Kabbalah Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  6. Review: Manfred Schulz (ed.: Entwicklungsträger in der DR Kongo. Entwicklungen in Politik, Wirtschaft, Religion, Zivilgesellschaft und Kultur (2007 Buchbesprechung: Manfred Schulz (Hrsg.: Entwicklungsträger in der DR Kongo. Entwicklungen in Politik, Wirtschaft, Religion, Zivilgesellschaft und Kultur (2007

    Directory of Open Access Journals (Sweden)

    Peter Ay

    2009-05-01

    Full Text Available Review of the edited volume: Manfred Schulz (ed.: Entwicklungsträger in der DR Kongo. Entwicklungen in Politik, Wirtschaft, Religion, Zivilgesellschaft und Kultur, Wien: Lit-Verlag 2007(= Spektrum 100; Berliner Reihe zu Gesellschaft, Wirtschaft und Politik in Entwicklungsländern 2007, ISBN 978-3825804251,755 pages. Besprechung des Sammelbandes: Manfred Schulz (Hrsg.: Entwicklungsträger in der DR Kongo. Entwicklungen in Politik, Wirtschaft, Religion, Zivilgesellschaft und Kultur, Wien: Lit-Verlag 2007 (= Spektrum 100; Berliner Reihe zu Gesellschaft, Wirtschaft und Politik in Entwicklungsländern, ISBN 978-3825804251, 755 Seiten.

  7. Micelle-derived catalysts for extended Schulz-Flory. Technical progress report, July 1, 1986--September 30, 1986

    Energy Technology Data Exchange (ETDEWEB)

    Abrevaya, H.

    1986-12-31

    The objective of this program is to develop a synthesis gas conversion catalyst with higher selectivity to liquid fuels, while maintaining catalytic activity and stability at least equivalent relative to state-of-the-art precipitated iron catalysts. During this quarter, the emphasis in the program has been the investigation of the hydrocarbon cutoff hypothesis with supported ruthenium catalysts. An alumina-supported catalyst with smaller than 20{Angstrom} ruthenium particles was tested under conditions of maximal water gas shift activity. During this test more than 90% of the water made in the Fischer-Tropsch synthesis reaction was converted to H{sub 2}. However, the extent of ruthenium metal agglomeration was not reduced. Accordingly, it was not possible to conclude whether hydrocarbon cutoff occurs with smaller than 20{Angstrom} ruthenium particles on {gamma}-alumina. A ruthenium catalyst prepared on Y-type zeolite had 20{Angstrom} or smaller ruthenium particles according to STEM examination and a 15{Angstrom} average ruthenium metal particle size according to EXAFS examination. The ruthenium metal particle size was stable during the test with this catalyst. The hydrocarbon product distribution was Anderson-Schulz-Flory with no cutoff up to a carbon number of 160. A well-dispersed titania-supported ruthenium catalyst is going to be evaluated during the next quarter in order to determine whether hydrocarbon cutoff occurs.

  8. An Analysis of the Observed Low-level Structure of Rapidly Intensifying and Mature Hurricane Earl (2010)

    Science.gov (United States)

    2014-01-01

    structure. J. Atmos. Sci. 49: 919–942. Marks FD, Black PG, Montgomery MT, Burpee RW. 2008. Structure of the eye and eyewall of hurricane Hugo (1989...structure of rapidly intensifying and mature hurricane Earl (2010) Michael T. Montgomery,a* Jun A. Zhangb and Roger K. Smithc aDepartment of Meteorology...Naval Postgraduate School, Monterey, CA, USA bNOAA Hurricane Research Division, Miami, FL, USA cMeteorological Institute, Ludwig Maximilians, University

  9. A Tale of Two Empires? The Earl's Court Spanish Exhibition (1889

    Directory of Open Access Journals (Sweden)

    Kirsty Hooper

    2014-10-01

    Full Text Available This paper proposes that the forgotten Earl's Court Spanish Exhibition of 1889 provides a valuable window onto the complex relationship between the British and Spanish Empires at the moment of one's expansion and the other's fragmentation. Part I assesses the limited archival evidence together with media reports from both Spain and Britain to uncover the Exhibition’s origins in London’s Spanish expatriate business community and its takeover by British businessmen with interests in Latin America. Part II reconstructs the Exhibition’s layout and contents in order to explore how the contrasting geocultural logics of Spain’s renewed self-projection as a modern Empire and the longstanding British obsession with Spain’s Islamic past play out in the exhibitionary space and its contents. Part III analyses the rhetorical and imaginative strategies employed in British press coverage of the Exhibition, to argue that their coded representations of Spain and Spanish culture open the door to understanding the Exhibition in the context of Spain’s partial absorption into Britain’s nineteenth-century ‘informal empire.’

  10. Earl Sutherland (1915-1974) [corrected] and the discovery of cyclic AMP.

    Science.gov (United States)

    Blumenthal, Stanley A

    2012-01-01

    In 1945, Earl Sutherland (1915-1974) [corrected] and associates began studies of the mechanism of hormone-induced glycogen breakdown in the liver. In 1956, their efforts culminated in the identification of cyclic AMP, an ancient molecule generated in many cell types in response to hormonal and other extracellular signals. Cyclic AMP, the original "second messenger," transmits such signals through pathways that regulate a diversity of cellular functions and capabilities: metabolic processes such as lipolysis and glycogenolysis; hormone secretion; the permeability of ion channels; gene expression; cell proliferation and survival. Indeed, it can be argued that the discovery of cyclic AMP initiated the study of intracellular signaling pathways, a major focus of contemporary biomedical inquiry. This review presents relevant details of Sutherland's career; summarizes key contributions of his mentors, Carl and Gerti Cori, to the knowledge of glycogen metabolism (contributions that were the foundation for his own research); describes the experiments that led to his identification, isolation, and characterization of cyclic AMP; assesses the significance of his work; and considers some aspects of the impact of cyclic nucleotide research on clinical medicine.

  11. Review of The Earl of Abergavenny. Historical Record and Wreck Excavation CD-Rom

    Directory of Open Access Journals (Sweden)

    David Petts

    2003-06-01

    Full Text Available In early February 1805 a small fleet of East Indiamen accompanied by the frigate Weymouth set sail from Portsmouth heading first for Bengal and ultimately for China. However, barely had the voyage began when, following bad weather and confusion, one of the boats, the Earl of Abergavenny, struck the Shambles bank just off Portland Bill. Although the crew managed to free it, it was so badly damaged it sank while trying to make for the safety of Weymouth. Over 250 crew and passengers drowned. The wreck has until now been best known for causing the death of John Wordsworth, the ship's commander and brother of the poet William Wordsworth. This excellent CD report of archaeological investigations on the wreck site carried out since 1980 by the Weymouth Underwater Archaeological Group (WUAG brings us the full picture of the events leading up to the wreck, and a record of the remains found by the team of divers (Fig.1. The complex campaigns of diving have been carried out alongside extensive documentary and historical work. The huge amount of data created by this project has inevitably led to challenges for the WUAG regarding its publication (Cumming 2002. The decision to publish via a CD-ROM has allowed very large quantities of data and discussion to be published. The current version of the CD contains over 100,000 words of text, 1560 files and over 1000 illustrations (JPEGS. All for the grand price of 10 GBP. The volume can be browsed using a commercially available browser but is also supplied as compiled file using Web Compiler, which has the advantage of a search facility.

  12. A review of the Hexactinellida (Porifera) of Chile, with the first record of Caulophacus Schulze, 1885 (Lyssacinosida: Rossellidae) from the Southeastern Pacific Ocean.

    Science.gov (United States)

    Reiswig, Henry M; Araya, Juan Francisco

    2014-12-02

    All records of the 15 hexactinellid sponge species known to occur off Chile are reviewed, including the first record in the Southeastern Pacific of the genus Caulophacus Schulze, 1885, with the new species Caulophacus chilense sp. n. collected as bycatch in the deep water fisheries of the Patagonian toothfish Dissostichus eleginoides Smitt, 1898 off Caldera (27ºS), Region of Atacama, northern Chile. All Chilean hexactinellid species occur in bathyal to abyssal depths (from 256 up to 4142 m); nine of them are reported for the Sala y Gomez and Nazca Ridges, with one species each in the Juan Fernandez Archipelago and Easter Island. The Chilean hexactinellid fauna is still largely unknown, consisting of only 2.5 % of the known hexactinellid extant species. Further studies and deep water sampling are essential to assess their ecology and distribution, particularly in northern Chile.

  13. Human radiation studies: Remembering the early years. Oral history of radiologist Earl R. Miller, M.D., August 9 and 17, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-01

    Dr. Earl R. Miller was interviewed by representatives of US DOE Office of Human Radiation Research (OHRE). The interview covers Dr. Miller`s involvement with the Manhattan Engineer District, with total body irradiation, and heavy-ion therapy. Dr. Miller`s remembrances include wartime work on radiation exposure, Joe Hamilton, Neutron Therapy research, means of obtaining isotopes, consent forms, infinite laminograms, invention of a baby holder to alleviate exposure of radiological technicians in diagnostic procedures involving infants, and several personages.

  14. Human radiation studies: Remembering the early years. Oral history of radiologist Earl R. Miller, M.D., August 9 and 17, 1994

    International Nuclear Information System (INIS)

    1995-06-01

    Dr. Earl R. Miller was interviewed by representatives of US DOE Office of Human Radiation Research (OHRE). The interview covers Dr. Miller's involvement with the Manhattan Engineer District, with total body irradiation, and heavy-ion therapy. Dr. Miller's remembrances include wartime work on radiation exposure, Joe Hamilton, Neutron Therapy research, means of obtaining isotopes, consent forms, infinite laminograms, invention of a baby holder to alleviate exposure of radiological technicians in diagnostic procedures involving infants, and several personages

  15. Heliconema longissimum (Ortlepp, 1923) (Nematoda: Physalopteridae) from Pisodonophis boro (Teleostei: Ophichthidae) in Thailand, with remarks on the taxonomy of the Proleptinae Schulz, 1927.

    Science.gov (United States)

    Moravec, Frantisek; Taraschewski, Horst; Anantaphruti, Malinee Thairungroj; Maipanich, Wanna; Laoprasert, Thitiporn

    2007-01-01

    Physalopterid nematodes identified as Heliconema longissimum (Ortlepp, 1923) were collected from the stomach of rice-paddy eels Pisodonophis boro (Hamilton) (Anguilliformes: Ophichthidae) from two brackish-water localities (mangroves) in Thailand: one in Phan-Nga Province, southwestern Thailand, northeast of Phuket Island, and one in Ranong Province, near the border with Myanmar. Study of the morphology of this hitherto insufficiently known nematode species, including its first SEM examination, enabled a detailed redescription of H. longissimum. Present taxonomic problems in the subfamily Proleptinae Schulz, 1927 are discussed, where a new delimitation of Proleptus Dujardin, 1845, Heliconema Travassos, 1919 and Paraleptus Wu, 1927 is proposed based on the cephalic dentation. H. minnanensis [sic] Damin & Heqing, 2001 is transferred to Paraleptus Wu, 1927 as P. minnanensis (Damin & Heqing, 2001) n. comb. and Paraleptus chiloscyllii Yin & Zhang, 1983 transferred by Damin & Heqing (2001) to Heliconema, is retained in Paraleptus. H. ahiri Karve, 1941 is considered a junior synonym of H. longissimum (Ortlepp, 1923). The present finding of H. longissimum in Pisodonophis boro represents the first host record and the first record of this nematode from Thailand.

  16. A review and reanalysis of Bruno Schulz's "Erkrankungsalter schizophrener Eltern und Kinder [Age at onset of illness in schizophrenic parents and offspring]:" Zeitschrift für die gesamte Neurologie und Psychiatrie, 168, 709-721, 1940.

    Science.gov (United States)

    Sham, P C; Zerbin-Rüdin, E; Kendler, K S

    1995-01-01

    Nearly all previous evidence of the familial transmission of age at onset of schizophrenia has been in siblings and twins. In his paper, Bruno Schulz examined the age at onset distribution of schizophrenia in affected parent and offspring pairs, using a systematic series of ascertained cases (n = 106), as well as a second series of chronic in-patients (n = 36). The parent-offspring correlation in age at onset, for cases with a definite diagnosis in the systematically ascertained series, was estimated at 0.346 (95% confidence interval 0.134, 0.528). Schulz did not test for differences between the two series and between males and females, but our reanalysis, using correlational methods and a mixed linear model, did not detect any significant differences. These results are consistent with previous findings that age at onset of schizophrenia is influenced by familial factors which may be genetic.

  17. Earle W. Klosterman

    African Journals Online (AJOL)

    productivity may be quite constant. With calf production as the primary goal, productivity in a cow herd is often ... feed given to any animal is required for the maintenance of that animal. ... milk production may not be consistent with total feed costs if such ... most importance for increasing feed efficiency in beef cattle are feed ...

  18. Earle W. Klosterman

    African Journals Online (AJOL)

    feed which is returned as product in the calf is extremely small compared ... clearly has top priority. ~,·i1tattlre cow not nursing and/or carrying a calf should be marketed for beef. Feed costs, capital investment and labor requirements wiII not justify maintaining her ... cattle are feed intake or gain per unit of body weight and the ...

  19. The grass that they cut and trample and dig out and sprout roots again”: The Spiritual Baptist Church in Earl Lovelace’s The Wine of Astonishment

    Directory of Open Access Journals (Sweden)

    Maria Grau Perejoan

    2014-02-01

    Full Text Available Earl Lovelace’s fiction can be said to, ultimately, work as a force to give validity to the Creole culture created out of the coming together of many worlds in the Caribbean. As in his novel The Dragon Can’t Dance, which celebrated those Creole art forms around Carnival, in his next novel, The Wine of Astonishment (1982, i Lovelace celebrates yet another Creole institution, the Trinidadian African-derived church of the Spiritual Baptists. In the novel the Spiritual Baptist church, made to be seen as the darkness from which natives needed to be weaned by colonial authorities, is celebrated and acknowledged as one of the basis that allowed for the creation of a new society away from the colonial narrowness. In The Wine of Astonishment, the resistance put up by Spiritual Baptist practitioners, in spite of the prohibition and violence endured, is acknowledged, celebrated and recognised as one of the milestones in Caribbean history. This article will trace, as reflected in the novel, the evolution of the Spiritual Baptist church, and will analyse its symbolical relation to another art form created in the New World: the steel pan movement. All in all, this article will examine the survival of this Trinidadian African-derived church together with the emergence of the steelpan as two of the most salient testimonies of cultural survival and creolisation of the nation.

  20. Corrosion performance of MAO coatings on AZ31 Mg alloy in simulated body fluid vs. Earle's Balance Salt Solution

    Energy Technology Data Exchange (ETDEWEB)

    Wilke, Benjamin M. [Department of Mechanical Engineering, PO Box 755905, University of Alaska Fairbanks, Fairbanks, AK 99775 (United States); Zhang, Lei, E-mail: lzhang14@alaska.edu [Department of Mechanical Engineering, PO Box 755905, University of Alaska Fairbanks, Fairbanks, AK 99775 (United States); Li, Weiping; Ning, Chengyun [School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641 (China); Chen, Cheng-fu [Department of Mechanical Engineering, PO Box 755905, University of Alaska Fairbanks, Fairbanks, AK 99775 (United States); Gu, Yanhong [College of Mechanical Engineering, Beijing Institute of Petrochemical Technology, Beijing 102617 (China)

    2016-02-15

    Graphical abstract: - Highlights: • MAO coating is deposited on AZ31 Mg alloy by microarc oxidation. • Corrosion performance of MAO-coated AZ31 in EBSS vs. c-SBF is studied. • MAO-coated AZ31 exhibits enhanced corrosion resistance compared to bare AZ31. • Samples in EBSS show slower corrosion progression than the samples in c-SBF. • CO{sub 2} buffer and less chloride in EBSS cause corrosion rate gap in c-SBF and EBSS. - Abstract: Earle's Balance Salt Solution (EBSS) provides an alternative to the conventional simulated body fluids (c-SBF) and has been shown to better simulate the corrosion conditions in vivo. In this work, a series of tests were conducted to explore the corrosion performance of MAO-coated AZ31 samples in EBSS vs. c-SBF. Samples were produced by varying MAO process parameters and then immersed up to 21 days in both EBSS and c-SBF. The corrosion rates were evaluated by the electrochemical impedance spectroscopy and potentiodynamic scanning. Scanning electron microscope (SEM) was used to compare the progression of microcracks across the surface of the coatings. The evaluation of cross-sectional thickness showed an increase in MAO coating thickness with the process voltage. MAO samples with a thicker coating generally have higher impedance and lower current density at the initial immersion time point of 0.5 h. Samples in EBSS showed higher initial impedance and lower current density values as compared to c-SBF counterparts for all process groups. Samples in EBSS demonstrated a much slower corrosion rate than c-SBF samples because of the decreased chloride content and CO{sub 2} buffering mechanism of the EBSS.

  1. Assessment of dietary exposure to flavouring substances via consumption of flavoured teas. Part II: transfer rates of linalool and linalyl esters into Earl Grey tea infusions.

    Science.gov (United States)

    Orth, Anne-Marie; Poplacean, Iulia; Fastowski, Oxana; Engel, Karl-Heinz

    2014-01-01

    The assessment of dietary exposure via the consumption of flavoured foods is a key element of the safety evaluation of flavouring substances. Linalyl acetate and linalool are the major flavouring substances in Earl Grey teas; the objective of this study was to determine their transfer rates from the tea leaves into the tea beverage upon preparation of a hot water infusion. Spiking experiments revealed a transfer rate of 66% for linalool. In contrast, the transfer rate for linalyl acetate was only 1.9%; in turn, the hydrolysis product linalool (17.0%) and a spectrum (19.9%) of degradation and rearrangement products (monoterpene alcohols, esters and hydrocarbons) were present in the tea beverage. The transfer rates were shown to be proportional to the length of the infusion. The impact of the hot water treatment on the enantiomeric compositions of linalyl acetate and linalool was determined, and structure-dependent experiments were performed by variation of the acyl and the alcohol moiety of the monoterpene ester. Comparative dietary exposure assessments demonstrated the need to take correction factors based on the experimentally determined transfer rates into account. Based on tea consumption data from the UK National Diet and Nutrition Survey (2000/2001), the exposure to linalyl acetate ranges from 0.2 mg day(-1) (average) to 1.8 mg day(-1) (high). The corresponding values for linalool are 4.2 mg day(-1) (average) and 46.6 mg day(-1) (high). The exposure of linalool via consumption of the tea beverage is approximately 26 times higher than that of linalyl acetate, although in the flavoured tea leaves the median content of linalyl acetate is approximately 1.8 times higher than that of linalool.

  2. Corrosion performance of MAO coatings on AZ31 Mg alloy in simulated body fluid vs. Earle's Balance Salt Solution

    International Nuclear Information System (INIS)

    Wilke, Benjamin M.; Zhang, Lei; Li, Weiping; Ning, Chengyun; Chen, Cheng-fu; Gu, Yanhong

    2016-01-01

    Graphical abstract: - Highlights: • MAO coating is deposited on AZ31 Mg alloy by microarc oxidation. • Corrosion performance of MAO-coated AZ31 in EBSS vs. c-SBF is studied. • MAO-coated AZ31 exhibits enhanced corrosion resistance compared to bare AZ31. • Samples in EBSS show slower corrosion progression than the samples in c-SBF. • CO 2 buffer and less chloride in EBSS cause corrosion rate gap in c-SBF and EBSS. - Abstract: Earle's Balance Salt Solution (EBSS) provides an alternative to the conventional simulated body fluids (c-SBF) and has been shown to better simulate the corrosion conditions in vivo. In this work, a series of tests were conducted to explore the corrosion performance of MAO-coated AZ31 samples in EBSS vs. c-SBF. Samples were produced by varying MAO process parameters and then immersed up to 21 days in both EBSS and c-SBF. The corrosion rates were evaluated by the electrochemical impedance spectroscopy and potentiodynamic scanning. Scanning electron microscope (SEM) was used to compare the progression of microcracks across the surface of the coatings. The evaluation of cross-sectional thickness showed an increase in MAO coating thickness with the process voltage. MAO samples with a thicker coating generally have higher impedance and lower current density at the initial immersion time point of 0.5 h. Samples in EBSS showed higher initial impedance and lower current density values as compared to c-SBF counterparts for all process groups. Samples in EBSS demonstrated a much slower corrosion rate than c-SBF samples because of the decreased chloride content and CO 2 buffering mechanism of the EBSS.

  3. Earl occurring and continuing effects

    International Nuclear Information System (INIS)

    Scott, B.R.; Hahn, F.F.

    1989-01-01

    This chapter develops health-risk models for early and continuing effects of exposure to beta or gamma radiation that could be associated with light water nuclear power plant accidents. The main purpose of the chapter is to provide details on each health-risk model and on the data used. Early and continuing effects considered are prodromal symptoms and nonneoplastic diseases that usually occur soon after a brief radiation exposure. These effects are generally associated with relatively high (greater than 1 Gy) absorbed organ doses. For most of the effects considered, there is an absorbed organ dose threshold below which no effects are seen. Some information is provided on health effects observed in victims of the Chernobyl power plant accident. Organs of primary interest, because of their high sensitivity or their potential for receiving large doses, are bone marrow, gastrointestinal tract, thyroid glands, lungs, skin, gonads, and eyes. Exposure of the fetus is also considered. Additional data and modeling techniques available since publication of the Reactor Safety Study were used to obtain models for morbidity and mortality

  4. Naval Weapons Station Earle Reassessment

    Science.gov (United States)

    2013-12-01

    property, or site is understood and its meaning (and ultimately its significance) within prehistory or history is made clear” (NPS 1991). A historic...components may lack individual distinction; or D. Information Potential—yielded, or is likely to yield, information important in prehistory or history...period in history or prehistory . Feeling Feeling is a property’s expression of the aesthetic or historic sense of a particular time period. Association

  5. Final Creech Air Force Base Capital Improvements Program Environmental Assessment

    Science.gov (United States)

    2013-11-01

    acts as a shell to softer, more vulnerable soils below. Lenses of caliche (sediment cemented together with sodium salts) and clay are also known to be...requirements. Contact Air Quality Program Manager YES Page 2 WATER QUALITY 99 CES/CEIEC, 652-2834 Any process that discharges to sanitary or industrial... Sanitary Wastewater Will the project result in the discharge of any sanitary wastewaters (e.g., wastewater from sinks, showers, toilets, etc)? A

  6. a dilemma for teachers in earl

    African Journals Online (AJOL)

    Kate H

    Education (MoE) prescribes that examinations should be school-based, this practice of .... Extract 2 is taken from a science lesson where it is evident that, as in extract 1, .... In one of the informal discussions with teacher Y, I asked her how she ...

  7. Dorothea Mantzel and Bernd Schulz. Francolin Illustrated School Dic

    African Journals Online (AJOL)

    rbr

    and wonder whether the Francolin Illustrated School Dictionary for Southern. Africa makes this distinction. I wonder ... The dictionary, the editors claim, is aimed at senior primary school learners who do not speak English as ... illustration of someone shooting with a bow and arrow at a target. When one turns to the headword ...

  8. The job satisfaction of black female academics | Schulze | South ...

    African Journals Online (AJOL)

    The aim of this research was to investigate the job satisfaction of black, female academics at a distance education institution. To this end, a phenomenological method was employed. By means of purposeful and snowball sampling, ten participants from different departments in the humanities were recruited and interviewed.

  9. Creech Air Force Base Resort Property in Indian Springs, Nevada. Environmental Baseline Survey Report

    Science.gov (United States)

    2011-04-01

    from the adjacent mountains. The alluvial sediments generally become finer- grained towards the centers of the valleys, where playa lake beds composed...internally drained basins. Following large storms, water may collect within playas , forming shallow lakes that evaporate rapidly due to high rates of...dutance far eoo~~&b away from travelers 011 the road sou.th would retruhmeats, aJ1d the truckers, bau.liog supplies to the Groom dutr1ct miles to

  10. Kõik, millest on raske loobuda (aga peab) / Mark Earls

    Index Scriptorium Estoniae

    Earls, Mark

    2003-01-01

    Katkend raamatust "Welcome to creative age. Bananas, Business and Death of Marketing", milles autor seab kahtluse alla mitmed turundusega seotud käibetõed, kutsub üles neist loobuma ja võtma suuna loovusele. Vt. ka: Sissejuhatuse asemel

  11. Rediscovering the Schulze-Hardy rule in competitive adsorption to an air-water interface.

    Science.gov (United States)

    Stenger, Patrick C; Isbell, Stephen G; St Hillaire, Debra; Zasadzinski, Joseph A

    2009-09-01

    The ratio of divalent to monovalent ion concentration necessary to displace the surface-active protein, albumin, by lung surfactant monolayers and multilayers at an air-water interface scales as 2(-6), the same concentration dependence as the critical flocculation concentration (CFC) for colloids with a high surface potential. Confirming this analogy between competitive adsorption and colloid stability, polymer-induced depletion attraction and electrostatic potentials are additive in their effects; the range of the depletion attraction, twice the polymer radius of gyration, must be greater than the Debye length to have an effect on adsorption.

  12. Effect Of Temperature On Hyalomma (Hyalomma) Impeltatum Schulze And Schlottke (Ixodoidea: Ixodidae)

    OpenAIRE

    Khalil, Galila M. [جليلة مصطفى خليل; Hagras, Ahmed E.

    1988-01-01

    The effect of 21, 25, 29 and 34°C on developmental period duration, weight of different stages in the life cycle and conversion efficiency in Hyalomma (H.) impeltatum Schuize and Schlottke was investigated at 75% relative humidity. Generally, egg incubation, larval and nymphal premolting and female preoviposition and oviposition periods were prolonged with the decrease in temperature. However, the egg incubation and preoviposition periods were the most greatly affected. Larval, nymphal and fe...

  13. Respek vir die liturgiese teks: J. Calvyn en J.S. Bach | Schulze | Acta ...

    African Journals Online (AJOL)

    Despite obvious differences in terms of historical and theological aspects between Calvin and Bach, both share a respect for the priority of the Biblical text in worship.The anomaly between Calvin's engagement in the versification of the Psalter and Bach's preference for the literal (rather than a versified) use of the Biblical ...

  14. Understanding youth motivation for water onion (Crinum thaianum J. Schulze conservation in Thailand

    Directory of Open Access Journals (Sweden)

    Nuttasun Athihirunwong

    2018-01-01

    Full Text Available Water Onion is an aquatic plant endemic to the coastal plains of southern Thailand. The species is listed as endangered on the IUCN Red List. Despite rapidly declining stocks, the species is not protected under any Thai legislation nor under the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES. At the local level, Water Onion is protected and conserved by young people and adults for various socio-economic reasons. The study explored the participation and underlying conservation motivations of 312 youths in Kapoe district, Ranong province. Using principal component analysis, the youth's motivation for Water Onion conservation was classified into four categories: pro-social, pro-nature, social image, and extrinsic. The results from a logit regression indicated that pro-nature is one of the key motivational factors enhancing actual youth participation in the protection and conservation of Water Onion. It is important for policy makers to understand the effects of various types of motivation on different policy mechanisms in order to craft more effective policies that can further enhance youth participation in conservation initiatives. Keywords: biodiversity conservation, endemic species, pro-nature motivation, water onion, youth

  15. Texture analysis by the Schulz reflection method: Defocalization corrections for thin films

    International Nuclear Information System (INIS)

    Chateigner, D.; Germi, P.; Pernet, M.

    1992-01-01

    A new method is described for correcting experimental data obtained from the texture analysis of thin films. The analysis employed for correcting the data usually requires the experimental curves of defocalization for a randomly oriented specimen. In view of difficulties in finding non-oriented films, a theoretical method for these corrections is proposed which uses the defocalization evolution for a bulk sample, the film thickness and the penetration depth of the incident beam in the material. This correction method is applied to a film of YBa 2 CU 3 O 7-δ on an SrTiO 3 single-crystal substrate. (orig.)

  16. Talking PACS: Part 2 - why should we change to PACS? | Schulze ...

    African Journals Online (AJOL)

    This article is a critical evaluation of the workflow within a film- and paper-based imaging department. It also illustrates how all the factors culminate to produce poor patient care and decreased productivity. Practical examples are provided within the Tygerberg Hospital scenario. The effect of international trends on the ...

  17. Schulze and Brand type a-IV dens invaginatus with radicular cyst: A rare case report

    Directory of Open Access Journals (Sweden)

    Rachita Chengappa

    2015-01-01

    Full Text Available Though a clinical examination may reveal a deep fissure or pit on the surface of an anterior tooth, radiographic examination is a more accurate approach to diagnose an invagination. Dens invaginatus is one of the common dental deformities, but the defect involving the root and its association with radicular cyst is still very uncommon. The objective of this case presentation is to report a case of radicular dens in dente, which is a rare dental anomaly. This case report shows that dens invaginatus with an open apex and a radicular cyst can be treated successfully using currently available materials.

  18. Eurosotside juht: usun, et SDE kuulub järgmisse valitsusse / Martin Schulz ; intervjueerinud Inga Höglund

    Index Scriptorium Estoniae

    Schulz, Martin, 1955-

    2011-01-01

    Intervjuu Euroopa Parlamendi sotsiaaldemokraatliku fraktsiooni juhiga sotsiaaldemokraatide võimalustest parempoolsete parteide kõrval, Eesti Sotsiaaldemokraatliku Erakonna võimalustest parlamendivalimistel, tööst Euroopa Parlamendis

  19. Ultrastructural studies on spermiogenesis and postcopulatory modifications of spermatozoa of Actinarctus doryphorus Schulz, 1935 (Arthrotardigrada: Halechiniscidae)

    DEFF Research Database (Denmark)

    Jørgensen, Aslak; Møbjerg, Nadja; Kristensen, Reinhardt Møbjerg

    1999-01-01

    . The spermiogenesis is very unique for a tardigrade, as the early spermatids are attached to giant nurse cells through cytoplasmatic bridges formed close to the spermatid nucleus. The nurse cell is characterized by a conspicuous labyrinth of rough endoplasmatic reticulum. In the posterior part of the testis...

  20. Palace of the Earl of Padul, Granada, Spain. A Milestone in a Crossroad

    Science.gov (United States)

    Lafuente-Bolívar, Francisco Javier; Santiago-Zaragoza, Juan Manuel; María Cruz-Valdivieso, Ana

    2017-10-01

    The Palace of the Counts of Padul is the most emblematic building of Padul, Province of Granada in Spain, being one of the most remarkable buildings of the region of the Valley of Lecrín. It is a building of undoubted historical value. It is classified as one of Cultural Interest, which means maximum level of protection of the Spanish legislation in historical heritage. In spite of being a historical symbol of Padul, most of the citizens ignore its importance. It was built in the first part of the XVII century. D. Antonio de Aróstegui y Zazo (knight of the Santiago order and a secretary of Felipe III) was its developer. He gave the building a noble character with an unusual design for this shire. The ground floor has an L shape. Besides, it has two floors and two squared towers, and standing out there is a third floor covered by a pitched roof. Also, it has load-bearing walls of masonry. Only the corners are built with carved stones. Deck is built with logs, and bricks, and wooden roof trusses. It looks like a solid simple house of civil architecture at the beginning of the Baroque style. Analyzing the urban morphology of Padul, the uniqueness of the plot is important related to the urban fabric. It is also remarkable its strategic position with respect to the historical roads that crossed there: The royal road that came from Granada heading to the Alpujarras, and leading to Motril and the road that starting in Malaga crossed through Alhama and arrived in Padul. It is clear the function of controlling the necessary passage towards the Lecrin Valley, the Alpujarras and the Mediterranean coast. Immediately after its declaration in 1981 as a National Monument, and despite this, it suffered an unfortunate intervention which has been maintained until today. The council of Padul would like to acquire it presenting a project for its recovery. This situation provoked the invitation of the council to the University of Granada to help with that. And this would allow the students of Final Project Degree of the Higher Technical School of Building Engineering to have it as a real object to work. By focusing our attention on this building, it is intended to preserve its valuable heritage, showing its history, proposing technical solutions for preservation, and finally, to make the Casa Grande popular for the residents of Padul and all visitors.

  1. Earle K. Plyler Prize Lecture: The Three Pillars of Ultrafast Molecular Science - Time, Phase, Intensity

    Science.gov (United States)

    Stolow, Albert

    We discuss the probing and control of molecular wavepacket dynamics in the context of three main `pillars' of light-matter interaction: time, phase, intensity. Time: Using short, coherent laser pulses and perturbative matter-field interactions, we study molecular wavepackets with a focus on the ultrafast non-Born-Oppenheimer dynamics, that is, the coupling of electronic and nuclear motions. Time-Resolved Photoelectron Spectroscopy (TRPES) is a powerful ultrafast probe of these processes in polyatomic molecules because it is sensitive both electronic and vibrational dynamics. Ideally, one would like to observe these ultrafast processes from the molecule's point of view - the Molecular Frame - thereby avoiding loss of information due to orientational averaging. This can be achieved by Time-Resolved Coincidence Imaging Spectroscopy (TRCIS) which images 3D recoil vectors of both photofragments and photoelectrons, in coincidence and as a function of time, permitting direct Molecular Frame imaging of valence electronic dynamics during a molecular dynamics. Phase: Using intermediate strength non-perturbative interactions, we apply the second order (polarizability) Non-Resonant Dynamic Stark Effect (NRDSE) to control molecular dynamics without any net absorption of light. NRDSE is also the interaction underlying molecular alignment and applies to field-free 1D of linear molecules and field-free 3D alignment of general (asymmetric) molecules. Using laser alignment, we can transiently fix a molecule in space, yielding a more general approach to direct Molecular Frame imaging of valence electronic dynamics during a chemical reaction. Intensity: In strong (ionizing) laser fields, a new laser-matter physics emerges for polyatomic systems wherein both the single active electron picture and the adiabatic electron response, both implicit in the standard 3-step models, can fail dramatically. This has important consequences for all attosecond strong field spectroscopies of polyatomic molecules, including high harmonic generation (HHG). We discuss an experimental method, Channel-Resolved Above Threshold Ionization (CRATI), which directly unveils the electronic channels participating in the attosecond molecular strong field ionization response [10]. This work was supported by the National Research Council of Canada and the Natural Sciences & Engineering Research Council.

  2. Fortunatus in Disguise: The Adventures of Master F.I. Edward de Vere, Earl of Oxford

    OpenAIRE

    Pigman, G. W., III

    2012-01-01

    Like most "Stratfordians," I did not think that Oxfordians "deserved the compliment of rational opposition," as Jane Austen would say, and never would have reviewed this book had I not encountered a footnote in the fascinating, tortured correspondence between Sigmund Freud (a notorious Oxfordian in later life) and his fiancée Martha Bernays. If scholars of their caliber, three of the world’s most eminent historians of psychoanalysis, can take Oxfordianism seriously, Shakespeareans need to spe...

  3. Time budget of South African cliff swallows during breeding | Earlé ...

    African Journals Online (AJOL)

    The use of time by the South African cliff swallow was determined and use of energy calculated by using equations for predicting standard metabolic rate and the cost of flight. The highest daily energy expenditure was during the feeding of nestlings when 9,22 h were spent foraging. The cost of 127 kJ for building a nest is ...

  4. Hamilton and Zuk 1982, Earlé et al. 1991, Bennet et al. 1995, Jovani

    African Journals Online (AJOL)

    spamer

    hatching (Graczyk et al. 1994). ... Its success has been attributed to the ... Future success of avian blood parasites and/or ... rates (Trager 1939, Roberts 1968), but this does not happen ... The insects of sub-Antarctic Marion and Prince Edward.

  5. 78 FR 12091 - Brian Earl Cressman, M.D.; Decision and Order

    Science.gov (United States)

    2013-02-21

    ... Disposition (``MSD''), seeking: (1) Summary disposition; and (2) a recommendation that ``the Respondent's DEA COR as a practitioner be revoked based on the Respondent's lack of a state license.'' MSD, at 5. A...'s ACSC was attached to the MSD. MSD App. A. Additionally, the Government included a printout from...

  6. Babesia peircei sp. nov. from the jackass penguin | Earlé | African ...

    African Journals Online (AJOL)

    An avian piroplasm, Babesia peircei sp. nov. is described from the jackass penguin Spheniscus demersus. Morphological differences between Babesia peircei sp. nov. and the other valid Babesia spp. are discussed together with the possible vectors.

  7. Many Shades of Earl Grey - Chinese Social Media as a Mirror of Chinese Culture

    NARCIS (Netherlands)

    Peverelli, P.J.

    2015-01-01

    Social media are currently probably the quickest way to learn what is on the minds of the people of a certain region. This holds even more in a collectivist culture like the Chinese in which individuals derive their social identity from the people they are interacting with. This monograph compares

  8. ПОЕТИЧНЕ БАЧЕННЯ ТЕКСТУ: ДОКАЗОВІ БАЗИ ТИПОЛОГІЧНОГО ПОРІВНЯННЯ ПРОЗИ Б. ШУЛЬЦА Й ПОЕЗІЇ Б.І. АНТОНИЧА / The poetic text vision: evidentiary basis of typological comparison of B. Schulz's prose and B.I. Antonych's poetry

    Directory of Open Access Journals (Sweden)

    Скрипник Ірина

    2015-12-01

    of typological comparison of B. Schulz's prose and B.I. Antonych's poetry. The article is a propaedeutic step to a wide long term authors' works research and can serve as a model for other similar studying, during which the issues of irrelation of kind and genre might occur. At the while studing the main objective is to explain the typological analysis of prose and poetry of these authors feasibility. After determining that the dominant in the analysis is the discourse of myth as a common reasoning of all works of both artists; and, based on the characteristics of the interwar two decades - a period when both Schulz and Antonych are the most active in their work, we conclude that the authors' texts fall into the mainstream of common European context (out of which we are mostly interested in Ukrainian and Polish aspects of the "expression of unutterable" that we consider the first evidence base of the subject comparative study. This concept stands first evidence base opportunities typological comparison of prose and poetry writers. The essence of the poetics of unutterable/ unspeakable lies in an attempt with the help of language and its expressive possibilities to sink in the ancient origins that in fact is the myth as a thought form and to define those things and concepts that are beyond human understanding, in subconsciousness. The second evidence base that allows us to compare lyric and epic works, is a significant presence of a literary diffusion phenomenon in the texts of both writers . Yet, all studies in this field have drawn attention to the genre diffusion within a literary kind until now. However, according to the specificity of B.I Antonych and B. Schultz works we are interested in class diffusion, which somewhat complicates finding a theoretical framework. Following the same way as the genre diffusion researchers, we turned to science and found interesting sub -kind of diffusion - ambipolar diffusion - simultaneous diffusion of opposite charged particles

  9. Heliconema longissimum (Ortlepp, 1923) (Nematoda: Physalopteridae) from Pisodonophis boro (Teleostei: Ophichthidae) in Thailand, with remarks on the taxonomy of the Proleptinae Schulz, 1927

    Czech Academy of Sciences Publication Activity Database

    Moravec, František; Taraschewski, H.; Thairungroj Anantaphruti, M.; Maipanich, W.; Laoprasert, T.

    2007-01-01

    Roč. 66, č. 1 (2007), s. 73-80 ISSN 0165-5752 R&D Projects: GA ČR(CZ) GA524/06/0170; GA MŠk LC522 Institutional research plan: CEZ:AV0Z60220518 Keywords : Heliconema * Pisodonophis * Thailand Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 1.125, year: 2007

  10. Genetic Analysis of earl field growth of loblolly pine clones and seedlings from the same full-sib families

    Science.gov (United States)

    Brian Baltunis; Dudley Huber; Tim Wite

    2006-01-01

    The Forest Biology Research Cooperative recently established a series of loblolly pine clonal trials known as CCLONES (Comparing Clonal Lines on Experimental Sites). There are three primary levels of genetic structure in this study (parental, full-sib family, clone) that strengthen the power of CCLONES for examining genetic mechanisms and interactions with cultural...

  11. Dr. Earl N. Meyer, in the Lab, with a Scalpel: A Murder Mystery as a Biochemistry Recruitment Tool

    Science.gov (United States)

    Vulcu, Felicia; Heirwegh, Meagan

    2015-01-01

    Increasing student participation in science is an ongoing challenge for many universities. In this active learning workshop, centered on inquiry and teamwork, we introduce high-school students to biochemistry and molecular biology techniques using a murder mystery activity. During this intensive 3 hr workshop, we engage students in a murder…

  12. Ação do fungo Beauveria bassiana (Balsamo Vuillemin, 1912 sobre a fase parasitária do carrapato Anocentor nitens (Neumann, 1897 Schulze, 1937 (Acari: ixodidae Action of the fungus Beauveria bassiana (Balsamo Vuillemin, 1912 on the parasitic phase of the tick Anocentor nitens (Neumann, 1897 Schulze, 1937 (Acari: ixodidae

    Directory of Open Access Journals (Sweden)

    Silvia Gonzalez Monteiro

    2003-06-01

    Full Text Available A patogenicidade do fungo Beauveria bassiana (isolado 986 foi avaliada no desenvolvimento da fase parasitária do Anocentor nitens, acompanhando o desenvolvimento de larvas não alimentadas até o estágio adulto. Foram utilizados dois tratamentos e um grupo controle com cinco repetições cada. No tratamento 1 (T1, as orelhas dos bovinos foram banhadas com a suspensão fúngica de 10(8 conídios ml-1; no tratamento 2 (T2, as orelhas foram banhadas com água destilada e espalhante adesivo. No grupo controle (C, as orelhas foram banhadas com água destilada. Após 24 horas dos tratamentos, as orelhas de cada animal foram infestadas com 100mg de larvas. Os parâmetros analisados, em cada tratamento, foram: número e peso de fêmeas recuperadas; períodos de pré-postura, postura, incubação, eclosão e longevidade; percentual de eclosão; peso da massa de ovos e da quenógina; índices de eficiência reprodutiva e nutricional. Verificou-se que, no T1 e T2, o número de fêmeas recuperadas, após 35 dias, foi significantemente menor (PThis study evaluated the pathogenicity of the fungus Beauveria bassiana (Isolate 986 on the development of the parasitic phase of Anocentor nitens by accompanying the development of unfed larvae until the adult stage. Two treated and one control group were used with five repetitions each. In the first treated group (T1, cattle ears were bathed with a fungal suspension of 10(8 conidia ml-1, second treated group (T2, the ears were bathed with distilled water and Tween 80 1% and the control group (C, the ears were bathed with distilled water. One day after treatment, the ears of each animal were infested with 100 mg of larvae. The parameters analyzed in each treatment were: number and weight of females recovered; periods of pre-oviposition, oviposition, incubation, eclosion and longevity; percentage of eggs hatched; weight of the egg mass and of females after oviposition. We found that in the two treated groups the number of females recovered was significantly lower (P<0.05 than in the control group. 35, 70 and 117 females were recovered from the T1, T2 and C, respectively. The females obtained from the surviving larvae of the treated groups did not suffer any deleterious effects from the entomopathogen studied.

  13. Does coronary Atherosclerosis Deserve to be Diagnosed earlY in Diabetic patients? The DADDY-D trial. Screening diabetic patients for unknown coronary disease.

    Science.gov (United States)

    Turrini, Fabrizio; Scarlini, Stefania; Mannucci, Caterina; Messora, Roberto; Giovanardi, Paolo; Magnavacchi, Paolo; Cappelli, Carlo; Evandri, Valeria; Zanasi, Andrea; Romano, Stefania; Cavani, Rita; Ghidoni, Italo; Tondi, Stefano; Bondi, Marco

    2015-07-01

    To evaluate if screening and treatment of asymptomatic coronary artery disease (CAD) are effective in preventing first cardiac event in diabetics. Diabetic patients without known CAD were randomly assigned to undergo a screening for silent myocardial ischemia followed by revascularization or to continue follow-up. The reduction of cardiac death (CD) or nonfatal myocardial infarction (MI) represented the primary aim; secondary aim was the prevention of heart failure (HF). From September 2007 to May 2012, 520 patients (62 years; 104 female) were enrolled. Silent CAD was found in 20 of 262 patients (7.6%), revascularization was performed in 12 (4.6%). After a mean follow-up of 3.6 years 12 events (4.6%) occurred in the study group and 14 (5.4%) in the follow-up (HR=0.849, 95% CI: 0.393-1.827, P=0.678). The occurrence of first HF episode did not differ between groups: 2 (0.8%) in screened and 7 (2.7%) in follow-up (HR=0.273, 95% CI: 0.057-1.314, P=0.083). Subgroup analysis revealed a significantly lower HF episodes among patients with intermediate cardiovascular risk (Log rank P=0.022). Additionally, when CD and MI were analysed within subgroups, a significant lower number of CDs was observed among older than 60 years (P=0.044). Screening and revascularization of silent CAD in diabetics, failed to demonstrate a significant reduction in cardiac events and HF episodes. However, our data indicate that further research is warranted in patients older than 60 years and those with an intermediate cardiovascular risk. CLINICALTRIALS.GOV: NCT00547872. Copyright © 2015. Published by Elsevier B.V.

  14. Observations of C-Band Brightness Temperature and Ocean Surface Wind Speed and Rain Rate in Hurricanes Earl And Karl (2010)

    Science.gov (United States)

    Miller, Timothy; James, Mark; Roberts, Brent J.; Biswax, Sayak; Uhlhorn, Eric; Black, Peter; Linwood Jones, W.; Johnson, Jimmy; Farrar, Spencer; Sahawneh, Saleem

    2012-01-01

    Ocean surface emission is affected by: a) Sea surface temperature. b) Wind speed (foam fraction). c) Salinity After production of calibrated Tb fields, geophysical fields wind speed and rain rate (or column) are retrieved. HIRAD utilizes NASA Instrument Incubator Technology: a) Provides unique observations of sea surface wind, temp and rain b) Advances understanding & prediction of hurricane intensity c) Expands Stepped Frequency Microwave Radiometer capabilities d) Uses synthetic thinned array and RFI mitigation technology of Lightweight Rain Radiometer (NASA Instrument Incubator) Passive Microwave C-Band Radiometer with Freq: 4, 5, 6 & 6.6 GHz: a) Version 1: H-pol for ocean wind speed, b) Version 2: dual ]pol for ocean wind vectors. Performance Characteristics: a) Earth Incidence angle: 0deg - 60deg, b) Spatial Resolution: 2-5 km, c) Swath: approx.70 km for 20 km altitude. Observational Goals: WS 10 - >85 m/s RR 5 - > 100 mm/hr.

  15. Analysis of Single-Hole and Cross-Hole Tracer Tests Conducted at the Nye County Earl Warning Drilling Program Well Complex, Nye County, Nevada

    International Nuclear Information System (INIS)

    A. Umari; J.D. Earle; M.F. Fahy

    2006-01-01

    As part of the effort to understand the flow and transport characteristics downgradient from the proposed high-level radioactive waste geologic repository at Yucca Mountain, Nevada, single- and cross-hole tracer tests were conducted from December 2004 through October 2005 in boreholes at the Nye County 22 well complex. The results were analyzed for transport properties using both numerical and analytical solutions of the governing advection dispersion equation. Preliminary results indicate effective flow porosity values ranging from 1.0 x 10 -2 for an individual flow path to 2.0 x 10 -1 for composite flow paths, longitudinal dispersivity ranging from 0.3 to 3 m, and a transverse horizontal dispersivity of 0.03 m. Individual flow paths identified from the cross-hole testing indicate some solute diffusion into the stagnant portion of the alluvial aquifer

  16. "Byrummets ånd. Genius Loci/The Spirit of Urban Spaces"

    DEFF Research Database (Denmark)

    Reeh, Henrik

    2004-01-01

    byrum, Genius loci, Christian Norberg-Schulz, Sønder Boulevard, Berlin, nykultur, fortove, barndomserindringer......byrum, Genius loci, Christian Norberg-Schulz, Sønder Boulevard, Berlin, nykultur, fortove, barndomserindringer...

  17. [The effects of intraocular irrigating solutions on the human corneal endothelium (author's transl)].

    Science.gov (United States)

    Weekers, J F; Dethinne, M

    1978-11-01

    Human corneas from enucleated eyes get thicker during perfusion with B.S.S. On the contrary, their thickness decreases when perfused with T.C. Earle solution. Addition of reduced glutathion and adenosine does not change the results obtained with T.C. Earle. Histological study of the endothelium after a 24 hours perfusion demonstrates a better conservation of the cells with T.C. Earle and T.C. Earle glutathion--adenosine than with B.S.S.

  18. Long-term effects of spinal cord stimulation on angina symptoms and quality of life in patients with refractory angina pectoris--results from the European Angina Registry Link Study (EARL)

    DEFF Research Database (Denmark)

    Andréll, P; Yu, W; Gersbach, P

    2010-01-01

    To assess the long-term effect of spinal cord stimulation (SCS) on angina symptoms and quality of life in patients with refractory angina pectoris defined as severe angina due to coronary artery disease resistant to conventional pharmacological therapy and/or revascularisation....

  19. Developing Dynamic Reference Models and a Decision Support Framework for Southeastern Ecosystems: An Integrated Approach

    Science.gov (United States)

    2015-06-01

    Tuesday afternoon, March 25, and the solution breakout group discussions took place on Wednesday morning, March 26. Each breakout group presented...UK. Creech, M. N., L. K. Kirkman, and L. A. Morris . 2012. Alteration and recovery of slash pile burn sites in the restoration of a fire...Lesica, W. Morris , G. Oostermeijer, P. Quintana-Ascencio, A. Stanely, T. Ticktin, R. Valverde, and J. Williams. 2011. How do plant ecologists use matric

  20. Perceptions of brick architecture : interview with Jeroen Geurst

    NARCIS (Netherlands)

    Agyin, J.N.K.F.; Jenniskens, D.P.H.

    Jeroen Geurst (1960) studied architecture at Delft University of Technology and co-founded Geurst & Schulze architects with Rens Schulze in 1984. Over the span of more than three decades, the office has developed a large oeuvre of predominantly brick buildings. Geurst furthermore recently

  1. Technical, economic, environmental and social follow-up of innovating farm-based small methanization plants: BIOGAZ PLUS - Report after a 12-month follow-up; Installation: EARL Guilbaud - Report after a 15-month follow-up; Installation: GAEC Des Buissons - Report after a 12-month follow-up

    International Nuclear Information System (INIS)

    Lalanne, Mathieu; Cordelier, Marine; Pouech, Philippe; Thual, Julien; Bastide, Guillaume; Faure, Benoit; Faure, Jean-Marie; Bousquet, Dominique; El Habti, Audrey; L'Heriau, Germain; Guianvarch, David; Farcy, Alexandre; Banville, Sandrine; Chauvin, Damien; Frederic, Sylvain; Haumont, Francois; Guilbaud, Gerard; Leroux, Yannick; Tronc, Jean-Sebastien; Menard, Anthony

    2015-08-01

    This document contains three follow-up reports, each concerning a small farm-based methanization unit. For each one, the report proposes a technical description (operation, provisional exploitation assessment, process principle and implementation, installed instrumentation), describes the status of production (noticed dysfunctions and identified causes, returns on experience), an operation assessment after 12 or 15 months in terms of biological performance (composition of input mixture, methane generation potential, organic load) and energetic performance (biogas, electric, thermal and energetic assessments), an assessment of environmental and social performance (time spent, energy efficiency, greenhouse gas assessment, integration of the installation within the farm, risk and pollution assessment), an economic assessment in terms of investment, of operating statements and of indicators of financial profitability. Results of composition measurements performed on input materials and digestates are provided

  2. Risk Assessment and Clinical Risk Management for Young Antisocial Children: The Forgotten Group

    OpenAIRE

    Augimeri, Leena; Child Development Institute; Walsh, Margaret; Child Development Institute; Woods, Sarah; Child Development Institute; Jiang, Depeng; University of Manitoba

    2012-01-01

    Centre for Children Committing Offences (CCCO), at Child Development Institute (CDI) in Toronto, Canada, developed Early Assessment Risk Lists (EARL-20B for boys; EARL-21G for girls), for young children at-risk for future criminality. In this first EARL prospective longitudinal study, 573 boys and 294 girls who participated in SNAP®, a gender-specific evidencebased model for at-risk children (6-11 years), 8.2% of boys and 3.1% of girls had registered criminal offences at follow up (mean age 1...

  3. Immunologic Control by Oral Vaccines of Diarrheal Disease Due to Enterotoxigenic Escherichia coli and shigella

    Science.gov (United States)

    1986-09-01

    Clements UL, Lanata C, Sears, S, Honda T, Young CR, Finkelstein RA. Evaluation in humans of attenuated Vibrio cholerae El Tor Ogawa Strain Texas Star...DE, Bareett TJ, YouW (CR, Levine WM, Blake PA. Impact of epidemic cholera in a previously uninfected island population: evaluation of a new...Sack, D.A., Wells, J.G., Feeley, J.C., Sack, R.B., Creech, W.M., Kapikian, A.Z., Gangarosa, E.J. 1976. Traveler’s flarrhea in Mexico . A Prospective

  4. Hemingway oli KGB, filmistaar Errol Flynn natside agent? / Tõnis Erilaid

    Index Scriptorium Estoniae

    Erilaid, Tõnis, 1943-

    2009-01-01

    John Earl Haynes, Harvey Klehr ja Alexander Vassiliev väidavad oma raamatus "Spies : The Rise and Fall of the KGB in America", et Ernest Hemingway oli 1940ndail aastail KGB ning Errol Flynn 1930ndatel aastatel natside agent

  5. Steel fiber replacement of mild steel in prestressed concrete beams

    Science.gov (United States)

    2010-10-01

    In traditional prestressed concrete beams, longitudinal prestressed tendons serve to resist bending moment and : transverse mild steel bars (or stirrups) are used to carry shear forces. However, traditional prestressed concrete I-beams : exhibit earl...

  6. Disease: H01788 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available veloping potentially life-threatening complications, such as deep vein thrombosis (DVT), pulmonary embolism (PE), and recurrent bleed...ing. Most cases arise from sporadic mutations in one or more genes involved in earl

  7. Strategies for getting through labor

    Science.gov (United States)

    ... to stay comfortable. Keep your mind busy. Bring books, photo albums, games, or other things that will ... Flood P, Rolins MD. Anesthesia for obstetrics. In: Miller RD, ed. Miller's ... PA: Elsevier Saunders; 2015:chap 77. Mertz MJ, Earl ...

  8. Plaadid / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2002-01-01

    Uutest plaatidest Suede "A New Morning", Maria Kirsi "Burning Flame", Jüri Homenja "Hommennium III", "Dogtown ans Z-Boys", Diana King "respect", No Angels "Now...Us!", Default "The Fallout", Steve Earle "Jerusalem"

  9. 75 FR 27620 - Qualification of Drivers; Exemption Renewals; Vision

    Science.gov (United States)

    2010-05-17

    ..., Sr., Levi A. Brown, Charlie F. Cook, Clifford H. Dovel, Arthur L. Fields, John W. Forgy, Glenn E. Gee..., Monte L. Purciful, Luis F. Saavedra, Earl W. Sheets, Robert V. Sloan, Steven L. Valley, Thomas E. Voyles...

  10. Bedrock Geologic Map of Charlotte,�Vermont

    Data.gov (United States)

    Vermont Center for Geographic Information — Digital Data from VG09-5 Gale, M., Kim, J., Earle, H., Clark, A., Smith, T., and Petersen, K., 2009, Bedrock Geologic Map of Charlotte, Vermont: VGS Open-File Report...

  11. Conservation and Multiplication of Endangered Plants :1. Leptophonia Reticulata (Retz.) Wight. & Arn

    OpenAIRE

    Shukla, Jitendra K.; Kasera, Pawan K.; Chawan, D.D.

    2001-01-01

    The present communication deals with the vegetative propagation through air layering technique in L. reticluata, know as Jivanti in Ayurvedic medicinal plant, The results reveal tat ceradik treated twigs produced profuse and earl rooting with higher survival percentage

  12. Disease: H00811 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available McMillin MJ, Below JE, Shively KM, Beck AE, Gildersleeve HI, Pinner J, Gogola GR, Hecht JT, Grange DK, Har...ris DJ, Earl DL, Jagadeesh S, Mehta SG, Robertson SP, Swanson JM, Faustman EM, Meff

  13. Pathophysiology of immune thrombocytopenic purpura: a bird's-eye ...

    African Journals Online (AJOL)

    ... or release into the circulation? Doan et al.22 examined a number of spleens from .... purpura (Cooper N, Bussel J. The pathogenesis of immune thrombocytopaenic purpura. Br J Haematol. 2006 ...... Cremer M, Schulze H, Linthorst G, et al.

  14. Dvorjanskoje gnezdo : glava iz knigi 'ESTICA : kultura i istorija' / Jüri Kuuskemaa

    Index Scriptorium Estoniae

    Kuuskemaa, Jüri, 1942-

    1998-01-01

    Rägavere mõisa härrastemajast, arvatav arhitekt Johann Schulz. Selle taastamisest kultuurikeskuse tarvis. Sisekujundaja Leila Pärtelpoeg, skulptor Cornelius Tamm. Maali- ja mööblikollektsioonist

  15. Knee osteoarthritis and perceived social support amongst patients in ...

    African Journals Online (AJOL)

    Temitope Ilori

    2016-06-29

    Jun 29, 2016 ... long been linked with health and illness; for instance married adults have a lower ... recover faster than unmarried adults.13 Social support can be defined as those ..... Martire LM, Lustig AP, Schulz R, Miller GE, Helgeson VS.

  16. Ich spreche Deutsch: A User's Report

    Science.gov (United States)

    Glassar, Sheila

    1969-01-01

    The textbook under discussion, "Ich spreche Deutsch" by Heinz Griesbach and Dora Schulz (London-Harlow: Longmans-Hueber, 1966), is intended to be a one-year introduction to German, particularly for less academic pupils and students. (FWB)

  17. An Antropologist of Sound

    DEFF Research Database (Denmark)

    Groth, Sanne Krogh

    2015-01-01

    PROFESSOR PORTRAIT: Sanne Krogh Groth met Holger Schulze, newly appointed professor in Musicology at the Department for Arts and Cultural Studies, University of Copenhagen, to a talk about anthropology of sound, sound studies, musical canons and ideology.......PROFESSOR PORTRAIT: Sanne Krogh Groth met Holger Schulze, newly appointed professor in Musicology at the Department for Arts and Cultural Studies, University of Copenhagen, to a talk about anthropology of sound, sound studies, musical canons and ideology....

  18. Stopping-power and mass energy-absorption coefficient ratios for Solid Water

    International Nuclear Information System (INIS)

    Ho, A.K.; Paliwal, B.R.

    1986-01-01

    The AAPM Task Group 21 protocol provides tables of ratios of average restricted stopping powers and ratios of mean energy-absorption coefficients for different materials. These values were based on the work of Cunningham and Schulz. We have calculated these quantities for Solid Water (manufactured by RMI), using the same x-ray spectra and method as that used by Cunningham and Schulz. These values should be useful to people who are using Solid Water for high-energy photon calibration

  19. ADAPTIVE SELECTION OF AUXILIARY OBJECTIVES IN MULTIOBJECTIVE EVOLUTIONARY ALGORITHMS

    Directory of Open Access Journals (Sweden)

    I. A. Petrova

    2016-05-01

    Full Text Available Subject of Research.We propose to modify the EA+RL method, which increases efficiency of evolutionary algorithms by means of auxiliary objectives. The proposed modification is compared to the existing objective selection methods on the example of travelling salesman problem. Method. In the EA+RL method a reinforcement learning algorithm is used to select an objective – the target objective or one of the auxiliary objectives – at each iteration of the single-objective evolutionary algorithm.The proposed modification of the EA+RL method adopts this approach for the usage with a multiobjective evolutionary algorithm. As opposed to theEA+RL method, in this modification one of the auxiliary objectives is selected by reinforcement learning and optimized together with the target objective at each step of the multiobjective evolutionary algorithm. Main Results.The proposed modification of the EA+RL method was compared to the existing objective selection methods on the example of travelling salesman problem. In the EA+RL method and its proposed modification reinforcement learning algorithms for stationary and non-stationary environment were used. The proposed modification of the EA+RL method applied with reinforcement learning for non-stationary environment outperformed the considered objective selection algorithms on the most problem instances. Practical Significance. The proposed approach increases efficiency of evolutionary algorithms, which may be used for solving discrete NP-hard optimization problems. They are, in particular, combinatorial path search problems and scheduling problems.

  20. Intermodal transportation from European seaports into CIS and Baltic region / Walter Schulze-Freyberg = Интермодальные перевозки из европейских морских портов в страны СНГ и балтийск

    Index Scriptorium Estoniae

    Schulze-Freyberg, Walter

    2003-01-01

    Ettekanne 3.-4. detsembrini 2003 Tallinnas toimunud rahvusvahelisel konverents-näitusel "Logistics and transport in international trade" tutvustab Saksamaa transpordiettevõttes POLZUG GmbH väljatöötatud ja rakendatud raudteekonteinervedudel põhinevat transpordisüsteemi. Kaart

  1. Anwendung des autogenen Trainings im Kindesalter

    OpenAIRE

    Sühling, Nikola

    2004-01-01

    The autogenic training was developed by J.H.Schulz in the period between 1912-1920 based on the experiences of his hypnosis patients. These reported of a regular occurrence of certain perceptions at the beginning of the treatment. J.H.Schulz derived six exercises from this experience, through which the patient is said to get relaxed. Among others these exercises contain the idea to get warm and heavy arms and legs. Furthermore, physical reactions in the abdomen, thorax and the head will be in...

  2. Human-Robot Interaction: A Survey

    Science.gov (United States)

    2007-01-01

    to the status of law by David Woods [320]. 7.3 Aviation and Air Traffic Control 249 Rich as these models and laws are, they cannot substitute for prac...M. Bennewitz, W. Burgard, A. B. Cremers , F. Dellaert, D. Fox, D. Hähnel, C. Rosenberg, N. Roy, J. Schulte, and D. Schulz, “Prob- abilistic...Thrun, M. Bennewitz, W. Burgard, A. B. Cremers , F. Dellaert, D. Fox, D. Hahnel, C. Rosenberg, N. Roy, J. Schulte, and D. Schulz, “MINERVA: A second

  3. Technical presentation: Next Generation Oscilloscopes

    CERN Multimedia

    PH Department

    2011-01-01

      Rohde & Schwarz "Next Generation Oscilloscopes" - Introduction and Presentation Agenda: Wednesday 23 March  -  09:30 to 11:30 (open end) Bldg. 13-2-005 Language: English 09.30 Presentation "Next Generation Oscilloscopes" from Rohde & Schwarz RTO / RTM in theory and practice Gerard Walker 10.15 Technical design details from R&D Dr. Markus Freidhof 10.45 Scope and Probe Roadmap (confidential) Guido Schulze 11.00 Open Discussion Feedback, first impression, wishes, needs and requirements from CERN All 11.30 Expert Talks, Hands on All Mr. Dr. Markus Freidhof, Head of R&D Oscilloscopes, Rohde & Schwarz, Germany; Mr. Guido Schulze, ...

  4. Play as a Basic Pathway to the Self: An Interview with Thomas S. Henricks

    Science.gov (United States)

    American Journal of Play, 2015

    2015-01-01

    Thomas S. Henricks is the J. Earl Danieley Professor of Sociology and Distinguished University Professor at Elon University. Since receiving his doctorate in sociology at the University of Chicago, Henricks has investigated the sociology of sports from the fandom of modern American professional wrestling to the relationship between sports and…

  5. Perfectionism, Stress, and Social (Dis)Connection: A Short-Term Study of Hopelessness, Depression, and Academic Adjustment among Honors Students

    Science.gov (United States)

    Rice, Kenneth G.; Leever, Brooke A.; Christopher, John; Porter, J. Diane

    2006-01-01

    This study tested models of perfectionism predicting psychological distress and academic adjustment and moderators and mediators of those associations in 2 successive cohorts of high-achieving university honors students (N = 499). Participants completed measures earl and late in the semester. Adaptive (high standards) and maladaptive…

  6. CRISPR/Cas9-mediated genome editing and gene replacement in plants: Transitioning from lab to field

    Science.gov (United States)

    The CRISPR/Cas9 genome engineering system has ignited and swept through the scientific community like wildfire. Owing largely to its efficiency, specificity, and flexibility, the CRISPR/Cas9 system has quickly become the preferred genome-editing tool of plant scientists. In plants, much of the earl...

  7. 1997 Hardwood Research Award Winner: "Automatic Color Sorting of Hardwood Edge-Glued Panel Parts"

    Science.gov (United States)

    D. Earl Kline; Richard Conners; Qiang Lu; Philip A. Araman

    1997-01-01

    The National Hardwood Lumber Association's 1997 Hardwood Research Award was presented to D. Earl Kline, Richard Conners, Qiang Lu and Philip Araman at the 25th Annual Hardwood Symposium for developing an automatic system for color sorting hardwood edge-glued panel parts. The researchers comprise a team from Virginia Tech University and the USDA Forest Service in...

  8. Dimensions of Modern Federalism.

    Science.gov (United States)

    Williams, Robert F.; And Others

    1995-01-01

    Encapsulates a series of brief essays exploring different aspects of modern federalism. Issues include further protection of individual rights extended through state constitutions and federalism and the world economy. Authors include Robert F. Williams, Earl H. Fry, and Daniel J. Elazar. (MJP)

  9. On the Use of a Cumulative Distribution as a Utility Function in Educational or Employment Selection.

    Science.gov (United States)

    1981-02-01

    economic applications. LI In the previous section, we discussed some properties of the TNU function. A GBU with a> 1 and b> 1 has similar characteristics...76/443 1 Dir :ctor, Office of Manpower Utilization Maxwell AFB, AL 36112 HQ, Marine Corps ( MPU ) BCB, Bldg. 2009 1 Dr. Earl A. Alluisi Quantico, VA

  10. Teleportatsioon köögis / Tõnu Kaalep

    Index Scriptorium Estoniae

    Kaalep, Tõnu, 1966-2018

    2009-01-01

    Muljeid rahvusvaheliselt disainimessilt Londonis Earls Courti näitusekeskuses 23.-26. septembrini 2009. Üheks peaürituseks oli Electroluxi "Design Lab 09" ülemaailmse üliõpilastööde võistluse finaal. Lühidalt parematest töödest

  11. U.S. Army’s Ground Vehicle Energy Storage R&D Programs & Goals

    Science.gov (United States)

    2010-11-10

    STATEMENT Approved for public release; distribution unlimited 13. SUPPLEMENTARY NOTES Briefing to ARPA-E BEEST Meeting 14. ABSTRACT NA 15...Program Collaboration & DOD Customers DOE Material Developers Battery Developers ANL USABC National Labs Universities Industrial Developers...qualification for military lead acid batteries; 6 water baths, 31 circuits, 1 thermal chamber • Electrochemical Research & Analysis Lab (EARL

  12. Regeneration of gill lamellae of the Indian horseshoe crab, Tachypleus gigas (Muller)

    Digital Repository Service at National Institute of Oceanography (India)

    Chatterji, A.; Alam, H.; Joshi, B.K.; Bhonde, R.R.

    taxa of other plant groups l ike Coniferales and Cycadales. The appea r- ance of Ginkgoales in India du r ing Early Cretaceous is significant. Ther e fore, the present study is aimed to trace its lineage from the earl i est record of fossils from...

  13. Acute and chronic pancreatitis: epidemiology and clinical aspects

    NARCIS (Netherlands)

    Spanier, B.W.M.

    2011-01-01

    In Nederland zijn de afgelopen jaren de incidentiecijfers en de ziekenhuisopnamen voor acute en chronische alvleesklierontsteking (pancreatitis) gestegen. De verwachting is dat deze blijven toenemen bij een vergrijzende samenleving. Uit de EARL-studie van Marcel Spanier komt naar voren dat bij acute

  14. OSHA: Five Years Later

    Science.gov (United States)

    Training, 1975

    1975-01-01

    An interview with Earl D. Heath, Director of the Office of Training and Education, Occupational Safety, and Health Division, U. S. Department of Labor, provides a discussion of the status of OSHA legislation in its training programs, in-house courses, and current course-development projects. (BP)

  15. Identification and Classification of Player Types in Massive Multiplayer Online Games Using Avatar Behavior

    Science.gov (United States)

    2011-08-01

    Kuan-Ta, Jhih-Wei Jiang, Polly Huang, Hao-Hua Chu, Chin-Laung Lei, and Wen-Chin Chen, “Identifying MMORPG Bots: A Traffic Analysis Approach”, EURASIP...in MMORPGs ”, Proceedings of DiGRA 2005 Conference: Changing Views – Worlds in Play Loeffelholz, Bernard, Earl Bednar, Kenneth W. Bauer, “Predicting

  16. die ontwikkeling van die menslike bewussyn ken wilber se aqal-teorie

    African Journals Online (AJOL)

    19 Feb 2010 ... The development of the human consciousness: Ken Wilber's AQAL theory. Kenneth Earl Wilber ... Wilber bestudeer dus die Psigologie van Carl Jung, Abraham Maslow, Stanislav Grof en Jean Piaget, sowel as Westerse .... within needs to be externalized so it doesn't spoil, like the manna in the desert that ...

  17. Immune modulation treatments

    DEFF Research Database (Denmark)

    Hviid, Malene Meisner; Macklon, Nick

    2017-01-01

    While advances in assisted reproductive techniques have been substantial, failure of the apparently viable embryo to implant remains a source of distress and frustration to patients and specialists alike. The unique maternal immunological response to the embryo and the notion that defects in earl...

  18. Arvustused / Andres Põllu

    Index Scriptorium Estoniae

    Põllu, Andres

    2000-01-01

    Uute heliplaatide Eric Clapton & B.B. King, B. B. "Riding with the King", Dreamphish "It Is I", Deftones "White Pony", Einstürzende Neubauten "Silence Is Sexy", Steve Earle "Transcendental Blues", The Filth And The Fury - A Sex Pistols Film, Cafe Del Mar tutvustus

  19. USA suursaadikuga Tallinna lahel / Katrin Kruss

    Index Scriptorium Estoniae

    Kruss, Katrin

    2007-01-01

    USA suursaadik Stanley Davis Phillips oma haridusteest, perekonnast, armastusest mere vastu, panusest isa Earl Phillipsi mööbliäri laiendamisse, golfiharrastusest, suursaadikute ettevalmistusest USA-s, suursaadiku residentsist Pirital ning uue saatkonnahoone otsingutest Tallinnas. Lisa: Stanley Davis Phillips

  20. PHTHALATE ESTER-INDUCED MALFORMATIONS ARE ASSOCIATED WITH CHANGES IN GENE EXPRESSION AND STEROID HORMONE PRODUCTION IN THE FETAL RAT TESTIS DURING SEXUAL DIFFERENTIATION

    Science.gov (United States)

    Phthalate ester-induced gubernacular ligament lesions are associated with reduced Insl3 gene expression in the fetal rat testis during sexual differentiation.Vickie S Wilson, Christy Lambright, Johnathan Furr, Joseph Ostby, Carmen Wood, Gary Held, L.Earl Gray Jr.U.S. EPA,...

  1. Suppression of Wnt1-induced mammary tumor growth and lower serum insulin in offspring exposed to maternal blueberry diet suggest early dietary influence on developmental programming

    Science.gov (United States)

    Despite the well-accepted notion that early maternal influences persist beyond fetal life and may underlie many adult diseases, the risks imposed by the maternal environment on breast cancer development and underlying biological mechanisms remain poorly understood. Here, we investigated whether earl...

  2. UNIVERSIDADE ESTADUAL DO SUDOESTE DA BAHIA

    African Journals Online (AJOL)

    TALLITA ROCHA

    2016-03-30

    Mar 30, 2016 ... Tallita de Oliveira Rocha. 1. , Janaina Silva Freitas. 1,2. , Elisa Susilene Lisboa dos Santos. 2. , Murilo. Marques Scaldaferri. 2. , Claudine Gonçalves de Oliveira. 2 ..... Dice LR (1945). Measures of the amount of ecological association between species. Ecology 26:297-302. Earl DA, Vonholdt BM (2012).

  3. 36 CFR 261.77 - Prohibitions in Region 8, Southern Region.

    Science.gov (United States)

    2010-07-01

    ... Service Registration Stations abutting the Chattooga River located at Highway 28, Low-Water Bridge, Earl's Ford, Sandy Ford, Highway 76, Woodall Shoals, or Overflow Bridge or unless authorized under special use... this section is prohibited. (d) Entering, going, riding, or floating upon any portion or segment of the...

  4. Balfour's Mission to Palestine: Science, Strategy, and the Inauguration of the Hebrew University in Jerusalem

    Science.gov (United States)

    Macleod, Roy

    2008-01-01

    In 1925, A.J. Balfour, first Earl Balfour and author of the famous "Balfour Declaration", attended the inauguration of the Hebrew University in Jerusalem. His education and experience of foreign policy equipped him to take a prominent role. However, the conditions of strife-torn Palestine weighed heavily upon him, and raised wider…

  5. 75 FR 9028 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2010-02-26

    ... YOKO MORI CO DANIEL GLENN COHEN DANIEL COHEN SHARONNA COLLINS THOMAS MICHAEL COOK RICHARD S CORDANI... CAROLINA UTA ALAN COOPER THOMAS ALLEN CHRISTOPHER DAVID ALY-STAVRINOU KATHERINE LILLIAN ANDERSEN PAUL EINAR... PETER C ERSKINE DOUGLAS GRAHAM EU KELVIN HAN FAGG THOMAS EARL FARRELL DOUGLAS FERGUSON ANNA YIP FERLAINO...

  6. Armageddon’s Lost Lessons: Combined Arms Operations in Allenby’s Palestine Campaign

    Science.gov (United States)

    2005-02-01

    followed closely behind, allowing air assets to keep pace with the fast-moving cavalry. By 1 October, Dam- ascus was occupied in force, and Allenby yet...Cyril B. Falls, Armageddon: 1918 (Philadelphia; New York: J.B. Lippincott Company, 1964), 62; Sav- age , Allenby of Armageddon, 210–11. 36. Earl Wavell

  7. Inquiry-based leading and learning : Inquiry-based working by school boards, school leaders and teachers and students’ inquiry habit of mind

    NARCIS (Netherlands)

    Luijk, E.

    2017-01-01

    Inquiry-based working is assumed to contribute to improving educational quality and to stimulate professional learning. It involves having an inquiry habit of mind, being data literate and creating a culture of inquiry in schools (based on Earl & Katz, 2006). The general aim of this study was to

  8. Estimation for the Rasch Model When Both Ability and Difficulty Parameters are Random.

    Science.gov (United States)

    1987-02-01

    Earles University of Leyden Air Force Human Resources Lab Education Research Center Brooks AFB, TX 78235 Boerhaavelaan 2 2334 EN Leyden Dr. Kent Eaton...Center for Naval Analysis NPRDC Code 13 4401 Ford Avenue San Diego, CA 92152-6800 P.O. Box 16268 Alexandria, VA 22302-0268 Ms. Kathleen Moreno Navy

  9. ANTIANDROGENIC EFFECTS OF VINCLOZOLIN ON MALE RATS ARE PARTIALLY ATTENUATED BY TESTOSTERONE PROPIONATE

    Science.gov (United States)

    ANTIANDROGENIC EFFECTS OF VINCLOZOLIN ON MALE RATS ARE PARTIALLY ATTENUATED BY TESTOSTERONE PROPIONATECynthia Wolf1,2 , Joe Ostby1, Jonathan Furr 1, Gerald A. LeBlanc2, and L. Earl Gray, Jr.11 US Environmental Protection Agency, NHEERL, RTD, RTP, NC 27711, 2 Departmen...

  10. A Case Study of the Effects of Dredging in Narrgansett Bay (RI, USA) on Winter Flounder Eggs

    Science.gov (United States)

    Seasonal dredging constraints have been established in several northeastern U.S. estuaries with the intent to protect winter flounder (Pseudopleuronectes americanus). A major source of concern is impacts on demersal eggs due to elevated sedimentation rates during the winter-earl...

  11. Die ontwikkeling van die menslike bewussyn: Ken Wilber se AQAL ...

    African Journals Online (AJOL)

    The development of the human consciousness: Ken Wilber's AQAL theory Kenneth Earl Wilber III, an integral philosopher, psychologist and mystic with an intelligence quotient of 160, was born on 31 January 1949 in Oklahoma City, Oklahoma, in the United States of. America, and is considered by some as one of the most ...

  12. The Lifetime Value of a Loyal Customer: What Can a Child Care Director Learn from Domino's Pizza and a Cadillac Dealer in Dallas?

    Science.gov (United States)

    Copeland, Margaret Leitch; Gimilaro, Susan

    2010-01-01

    In "The Service Profit Chain," Harvard Business School professors James Heskett, Earl Sasser, and Leonard Schlesinger (1997) offer two anecdotes--from Domino's Pizza and a Dallas Cadillac dealership--that illuminate the concept of valuing a lifetime customer. Experts estimate that the lifetime value of a loyal Domino's Pizza customer is $4,000 and…

  13. Organization and Integration of Learning Experiences in a Curriculum: A Case Study.

    Science.gov (United States)

    Everwijn, S. E. M.

    1983-01-01

    The literature on "organizers" by Ausubel, Earl, and Tyler provides clues to help teachers and students relate what has been learned in one subject to what is being learned in another. Problems of integration in a curriculum for student nurses are examined, and a solution to these problems is described. (RM)

  14. 75 FR 55594 - North Carolina; Emergency and Related Determinations

    Science.gov (United States)

    2010-09-13

    ... resulting from Hurricane Earl beginning on September 1, 2010, and continuing, are of sufficient severity and... State of North Carolina have been designated as adversely affected by this declared emergency: Beaufort..., Disaster Unemployment Assistance (DUA); 97.046, Fire Management Assistance Grant; 97.048, Disaster Housing...

  15. 75 FR 55810 - Massachusetts; Emergency and Related Determinations

    Science.gov (United States)

    2010-09-14

    ... Massachusetts resulting from Hurricane Earl beginning on September 1, 2010, and continuing, are of sufficient... affected by this declared emergency: Barnstable, Bristol, Dukes, Essex, Middlesex, Nantucket, Norfolk... Unemployment Assistance (DUA); 97.046, Fire Management Assistance Grant; 97.048, Disaster Housing Assistance to...

  16. EFFECTS OF DIBUTYL PHTHALATE IN MALE RABBITS FOLLOWING IN UTERO, ADOLESCENT OR POST-PUBERTAL EXPOSURE

    Science.gov (United States)

    Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or post-pubertal exposureTy T. Higuchi1, Jennifer S. Palmer1, L. Earl Gray Jr2., and D. N. Rao Veeramachaneni11Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort

  17. Impacts of climate change on water resources in Southern Africa: A Review

    CSIR Research Space (South Africa)

    Kusangaya, S

    2013-10-01

    Full Text Available in their projections. Moreso, others relied on use of a single GCM (e.g. Mujere and Mazvimavi, 2012). Additionally, only a few studies used RCM (e.g. Engelbrecht (2005); Schulze et al. (2005); Tadross et al. (2005)) despite these having a better spatial resolution...

  18. The Path of the Blind Watchmaker: A Model of Evolution

    Science.gov (United States)

    2011-04-06

    our countermeasures. Viruses evolve into new strains such that the antibodies produced due to vaccines are ineffective. Bacteria evolve into new...Maddison, Katja- Sabine Schulz, & Wayne P. Maddison. (2007). The Tree of Life Web Project. Zootaxa, 1668, 19-40. [42] Matt Ridley. (2000). The search for

  19. Internet Based Robot Control Using CORBA Based Communications

    Science.gov (United States)

    2009-12-01

    Proceedings of the IADIS International Conference WWW/Internet, ICWI 2002, pp. 485–490. [5] Flanagan, David , Farley, Jim, Crawford, William, and...Conference on Robotics andAutomation, ICRA’00., pp. 2019–2024. [7] Schulz, D., Burgard, W., Cremers , A., Fox, D., and Thrun, S. (2000), Web interfaces

  20. Toward Lifelong Visual Localization and Mapping

    Science.gov (United States)

    2013-06-01

    lab, Michael Benjamin, Rob Truax, Aisha Walcott, David Rosen, Mark VanMiddlesworth, Ross Finman, Elias Mueggler, and Dehann Fourie. They really made...S. Thrun, M. Beetz, M. Bennewitz, W. Burgard, AB Cremers , F. Dellaert, D. Fox, D. Hahnel, C. Rosenberg, N. Roy, J. Schulte, and D. Schulz. Proba

  1. Time-dependent Schroedinger equations with effective mass in (2 + 1) dimensions: intertwining relations and Darboux operators

    International Nuclear Information System (INIS)

    Cobian, Hector; Schulze-Halberg, Axel

    2011-01-01

    We construct Darboux transformations for time-dependent Schroedinger equations with position-dependent mass in (2 + 1) dimensions. Several examples illustrate our results, which complement and generalize former findings for the constant mass case in two spatial variables (Schulze-Halberg 2010 J. Math. Phys. 51 033521).

  2. Solar Photochemistry | Chemistry and Nanoscience Research | NREL

    Science.gov (United States)

    Generation in Semiconducting Single-Walled Carbon Nanotubes. Nat Comms 2015, 6, 8809. DOI: 10.1038/ncomms9809 . DOI: 10.1038/nchem.2348 Ihly, R.; Mistry, K. S.; Ferguson, A. J.; Clikeman, T. T.; Larson, B. W.; Reid -609. DOI: 10.1038/nchem.2496 Miller, E. M.; Kroupa, D. M.; Zhang, J.; Schulz, P.; Marshall, A. R

  3. Quantum and Carbon Nanomaterials | Chemistry and Nanoscience Research |

    Science.gov (United States)

    Heterojunctions. Nat. Chem., 2016, 8, 603. DOI: 10.1038/nchem.2496 Ihly, R., Dowgiallo, A-M., Yang, M., Schulz, P Single-Walled Carbon Nanotubes in a Low Dielectric Solvent. Nat. Commun., 2015, 6, 8809. 10.1038 . Nat. Energy, 2016, 1, 16033. DOI: 10.1038/nenergy.2016.33 Zhang, K., Wang, S., Qiu, J., Blackburn, J

  4. Competition of languages in the presence of a barrier

    OpenAIRE

    Schulze, Christian; Stauffer, Dietrich

    2007-01-01

    Using the Schulze model for Monte Carlo simulations of language competition, we include a barrier between the top half and the bottom half of the lattice. We check under which conditions two different languages evolve as dominating in the two halves.

  5. Chemical composition and anti-bacterial activity of essential oil from ...

    African Journals Online (AJOL)

    Yomi

    2012-01-24

    Jan 24, 2012 ... The fatty acid profiles of seed essential oil are characterized by considerable unsaturated fatty acids. (90.39%) including linoleic acid ..... sample clean-up steps (Schulz and Baranska, 2007). Therefore, FT-IR was employed ..... Squalene, olive oil, and cancer risk: A review and hypothesis. Cancer Epidemiol.

  6. Influence of air-sea fluxes on chlorine isotopic composition of ocean water: Implications for constancy in d37Cl- A statistical inference

    Digital Repository Service at National Institute of Oceanography (India)

    Shirodkar, P.V.; Xiao, Y.K.; Sarkar, A.; Dalal, S.G.; Chivas, A.R.

    WE, Ehrlich R, Klovan JE. J Math Geol 1981;13:331–4. Grassl H, Jost V, Ramesh Kumar MR, Schulz J, Bauer P, Schluessel P. The Hamburg Ocean atmosphere parameters and fluxes from satellite data (HOAPS): a climatological atlas of satellite derived air...

  7. Geochemistry of eastern Mediterranean sedimentary cycles : on the origin of Miocene to Pleistocene sapropels, laminites and diatomites

    NARCIS (Netherlands)

    Nijenhuis, Ivar Anders

    1999-01-01

    A brief history of sapropels The word "sapropel" first appears in the literature in 1904, when Potonié mentions that Prof. Dr. Schulze suggested that this word should be used as the international scientific term for Faulschlamm [Potonié, 1904]. Sapropel is a contraction of the literal translation of

  8. Fan texture of the compound Ba3Co2Fe244O41 pre-aligned in a magnetic field

    NARCIS (Netherlands)

    Huijser-Gerits, E.M.C.; Rieck, G.D.; Vogel, D.L.

    1970-01-01

    Samples of the ferrimagnetic material Ba3Co2Fe24O41, pre-aligned in a magnetic field and sintered at various temps., have been examd. for preferred orientation. Schulz's reflection technique and the standardizing method of Holland were used to det. quant. pole figures of several lattice planes. The

  9. Analysis of Unmanned Systems in Military Logistics

    Science.gov (United States)

    2016-12-01

    performance measures: customer satisfaction , flexibility, visibility, and trust. If we apply this explanation of Li and Schulze (2011) to the military...unmanned systems, initially, we aimed to define current and proposed unmanned applications in civilian-sector logistics and current military...aimed to define current and proposed unmanned applications in civilian-sector logistics and current military logistics challenges. Then, justifying

  10. South African Medical Journal - Vol 98, No 7 (2008)

    African Journals Online (AJOL)

    The Prevalence of Hepatitis B Co infection in a South African (SA) Urban government HIV Clinic · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. C Firhaber, A Reyneke, D Schulz, B Malope, B Malope, P Macphail, E Sanne, AD Biseglie, 541-544 ...

  11. South African Medical Journal - Vol 45, No 1 (1971)

    African Journals Online (AJOL)

    HC Falkson, EJ Schulz, Geoffrey Falkson. Plastics in Pharmacy and Medicine · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. TJ McCarthy. Gonadal dysgenesis, Turner's syndrome and phenotype in the South African Bantu · EMAIL FREE FULL TEXT EMAIL FREE ...

  12. The Army War College Review. Volume 2, Number 3, August 2016. Student Publications

    Science.gov (United States)

    2016-08-01

    natohq/opinions_128311.htm?selectedLocale=en. 99 President Schulz: We Need a Common Foreign and Security Policy (Washington, DC: HT Media Ltd, March...cause injury or death to persons or damage or destruction to objects.”13 The data stolen from defense contractors Boeing and Lockheed-Martin by Chinese

  13. The executive control network and symptomatic improvement in attention-deficit/hyperactivity disorder

    NARCIS (Netherlands)

    Francx, Winke; Oldehinkel, Marianne; Oosterlaan, Jaap; Heslenfeld, Dirk; Hartman, Catharina A.; Hoekstra, Pieter J.; Franke, Barbara; Beckmann, Christian F.; Buitelaar, Jan K.; Mennes, Maarten

    2015-01-01

    Background: One neurodevelopmental theory hypothesizes remission of attention-deficit/hyperactivity disorder (ADHD) to result from improved prefrontal top-down control, while ADHD, independent of the current diagnosis, is characterized by stable non-cortical deficits (Halperin & Schulz, 2006). We

  14. Theoretical Analyses of the Functional Regions of the Heavy Chain of Botulinum Neurotoxin

    Science.gov (United States)

    1994-01-01

    SE. Schulz GM. liallctt M. Effects of hb)tulinum toxin injections on speech in adductor spasmodic dysphonia . Neurology 1988,38:1220-1225. 3. Jankovic...hemifacial spasm. Mov Disord 1987:4:237-254. 5. Brin MF. Blitzer A, Fahn S, Gould W. Lovelace RE. Adductor laryngeal dystonia (spastic dysphonia ): treatment

  15. Malawi Medical Journal - Vol 26, No 3 (2014)

    African Journals Online (AJOL)

    Presentation of Primary Open Angle Glaucoma (POAG) at Lions Sight First Eye Hospital in Blantyre, Malawi · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. PC Kayange, HB Nkume, A Feyi-Waboso, K Kalua, G Msukwa, M Schwering Schulze, 60-62 ...

  16. Farmers' Willingness to Pay for Private Irrigation Supply in Nandom ...

    African Journals Online (AJOL)

    2017-05-01

    May 1, 2017 ... by income, age, farm size, engagement in an off-farm occupation, labour hours invested in farm operation, yield losses ... food insecurity and migration of their household members (Rademacher-Schulz & ... Ghana's current policy on agriculture water supply, the National Irrigation Policy,. Strategies and ...

  17. Hetero-interaction between Gouy-Stern double layers : charge and potential regulation

    NARCIS (Netherlands)

    Lyklema, J.; Duval, J.F.L.

    2005-01-01

    This issue of Advances is devoted to the memory of Hans-Joachim Schulze who, before his untimely death, made substantial contributions in the domains of flotation, wetting and particle interaction, often under adverse working conditions. Many of his publications involve hetero-interaction between

  18. Kirjad ja kriisid / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2001-01-01

    Sisu : Maimu Veske. Continental; Maeve Haran. Tangot tantsitakse kahekesi; Zana Muhsen. Müüdud; Ingo Schulze. 33 õnnehetke; Alistair MacLean. Karusaar; Suur uneraamat, koost. Raisa Vuohelainen; Arbujad, koost. Ants Oras; Friedrich Weissensteiner. Kuulsad enesetapjad; Peter A. Clayton. Vaaraode kroonika; Lillede keel

  19. Agrawal BK Density content of nuclear symmetry energy from ...

    Indian Academy of Sciences (India)

    ´Avila M. Nonadiabatic corrections to a quantum dot quantum computer working in adiabatic limit. 161. Ayyalasomayajula Krishna see Jain Jinesh. 179. Badescu ..... 807. Santhiah M see Jeevarekha A. 493. Satyanarayana V V see Sugathan P. 807. Sawhney K J S see Dhamgaye V P. 119. Schulz E see Couairon A. 221 ...

  20. Microscopic study of low-lying yrast spectra in Mo isotopes

    Indian Academy of Sciences (India)

    consistent calculations, which involved an optimized basis of eight major oscillator shells with the constraint of axial .... agreement with the values calculated by M¨oller et al [27] for 100 104Mo. 2. Calculational ..... [22] A Guessous, N Schulz, M Bentalab, E Lubkiewicz, J L Durell, C J Pearson, W R Phillips,. J A Shannon, W ...

  1. Treatment of psoriasis with cyclosporin | Nevin | South African ...

    African Journals Online (AJOL)

    South African Medical Journal. Journal Home · ABOUT · Advanced Search · Current Issue · Archives · Journal Home > Vol 85, No 11 (1995) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Treatment of psoriasis with cyclosporin. R.J. Nevin, E.J. Schulz. Abstract.

  2. Luksus ja lust : Tallinna rae hõbe- ja tinanõud = Luxury and Leisure : Silver and Pewter Tableware of the Tallinn Magistracy / Aita Raik

    Index Scriptorium Estoniae

    Raik, Aita

    2004-01-01

    Tallinna kullassepakunsti meistriteostest. Kahest väiksemast (Andreas Losson, 1620-ndate algus) ja kahest suuremast (Jakob Lange, 1639) maksukannust, kahest hõbekannust (Stanislaus Schulze, 17. saj. keskpaik), kahest rae kaitseväeülema ametisauast (suurem: Friedrich Schlegel, 1604-1605), väiksem 1610). Säilinud tinanõudest (kannud, peekrid, vaagnad, taldrikud, küünlajalad)

  3. Kuidas edasi? / Eesti SportHobuste Kasvatajate Selts

    Index Scriptorium Estoniae

    2014-01-01

    Ajakirjas Breeding avaldatud Oldenburgi aretusjuhi dr Schulze-Schleppinghoffi arvamusest Euroopa täkkude litsentseerimise ja uhkete show'de süsteemist, mis vähendab ennast tõestanud hobuste kohta aretusindeksi edetabelis ning annab eelise noortele täkkudele

  4. Feasibility of state of the art PET/CT systems performance harmonisation.

    Science.gov (United States)

    Kaalep, Andres; Sera, Terez; Rijnsdorp, Sjoerd; Yaqub, Maqsood; Talsma, Anne; Lodge, Martin A; Boellaard, Ronald

    2018-03-02

    The objective of this study was to explore the feasibility of harmonising performance for PET/CT systems equipped with time-of-flight (ToF) and resolution modelling/point spread function (PSF) technologies. A second aim was producing a working prototype of new harmonising criteria with higher contrast recoveries than current EARL standards using various SUV metrics. Four PET/CT systems with both ToF and PSF capabilities from three major vendors were used to acquire and reconstruct images of the NEMA NU2-2007 body phantom filled conforming EANM EARL guidelines. A total of 15 reconstruction parameter sets of varying pixel size, post filtering and reconstruction type, with three different acquisition durations were used to compare the quantitative performance of the systems. A target range for recovery curves was established such that it would accommodate the highest matching recoveries from all investigated systems. These updated criteria were validated on 18 additional scanners from 16 sites in order to demonstrate the scanners' ability to meet the new target range. Each of the four systems was found to be capable of producing harmonising reconstructions with similar recovery curves. The five reconstruction parameter sets producing harmonising results significantly increased SUVmean (25%) and SUVmax (26%) contrast recoveries compared with current EARL specifications. Additional prospective validation performed on 18 scanners from 16 EARL accredited sites demonstrated the feasibility of updated harmonising specifications. SUVpeak was found to significantly reduce the variability in quantitative results while producing lower recoveries in smaller (≤17 mm diameter) sphere sizes. Harmonising PET/CT systems with ToF and PSF technologies from different vendors was found to be feasible. The harmonisation of such systems would require an update to the current multicentre accreditation program EARL in order to accommodate higher recoveries. SUVpeak should be further

  5. Jimmy, Sinclair, and Jim: on the biographical trail of James Sinclair Ross Jimmy, Sinclair, and Jim: on the biographical trail of James Sinclair Ross

    Directory of Open Access Journals (Sweden)

    John J. O'Connor

    2008-04-01

    Full Text Available The deaths of Earle Birney and Robertson Davies late in 1995 reminded readers of Canadian literature that the old order—those writers born before the First World War—was quickly passing. Of the major figures born in the early years of this century (Birney, Davies, Callaghan, MacLennan, Ross, only Ross was still living at the beginning of 1996, albeit in very poor health in a nursing home in Vancouver. The deaths of Earle Birney and Robertson Davies late in 1995 reminded readers of Canadian literature that the old order—those writers born before the First World War—was quickly passing. Of the major figures born in the early years of this century (Birney, Davies, Callaghan, MacLennan, Ross, only Ross was still living at the beginning of 1996, albeit in very poor health in a nursing home in Vancouver.

  6. The contribution of thermal radiation to the thermal conductivity of porous UO2

    International Nuclear Information System (INIS)

    Bakker, K.; Kwast, H.; Cordfunke, E.H.P.

    1994-09-01

    The influence of cylindrical, spherical and ellipsoidal inclusions on the overall thermal conductivity was computed with the finite element technique. The results of these calculations were compared with equations that describe the effect of inclusions on the overall thermal conductivity. The analytical equation of Schulz that describes the effect of inclusions on the overall thermal conductivity is in good agreement with the results of the finite element computations. This good agreement shows that among a variety of porosity correction formulas, the equation of Schulz gives the best description of the effect of inclusions on the overall thermal conductivity. This equation and the results of finite element calculations allow us to compute the contribution of radiation to the overall thermal conductivity of UO 2 with oblate ellipsoidal porosity. The present radiation calculations show that Hayes and Peddicord overestimated the contribution of thermal radiation to the thermal conductivity. (orig.)

  7. Viscometric study of high-cis polybutadiene in toluene solution

    International Nuclear Information System (INIS)

    Mwllo, Ivana L.; Coutinho, Fernanda M.B.; Delpech, Marcia C.; Albino, Fernanda F.M.

    2006-01-01

    Viscometric measurements, in toluene solution at 30 deg C, were performed with high-cis polybutadiene synthesized by neodymium based catalyst. Six different equations were used to calculate intrinsic viscosities and viscosimetric constant values: Huggins, Kraemer, Martin and Schulz-Blaschke by graphic extrapolation, and Solomon-Ciuta, Deb-Chanterjee and again Schulz- Blaschke, through a single point determination. The molecular weight of the polymers was also determined applying Mark-Houwink-Sakurada equation using the values of intrinsic viscosity obtained by the six equations. The values of intrinsic viscosity and viscosity-average molecular weight obtained by the two methods were compared in order to verify the validity of the single point determination for high-cis polybutadiene. (author)

  8. Liquid abrasive pressure pot scoping tests report

    International Nuclear Information System (INIS)

    Archibald, K.E.

    1996-01-01

    The primary initiatives of the LITCO Decontamination Development group at the Idaho Chemical Process Plant (ICPP) are the development of methods to eliminate the use of sodium bearing decontamination chemicals and minimization of the amount of secondary waste generated during decontamination activities. In July of 1994, a Commerce Business Daily (CBD) announcement was issued by the INEL to determine commercial interest in the development of an in-situ liquid abrasive grit blasting system. As a result of the CBD announcement, Klieber ampersand Schulz issued an Expression of Interest letter which stated they would be interested in testing a prototype Liquid Abrasive Pressure Pot (LAPP). LITCO's Decontamination group and Kleiber ampersand Schulz entered into a Cooperative Research and Development Agreement (CRADA) in which the Decontamination Development group tested the prototype LAPP in a non-radioactive hot cell mockup. Test results are provided

  9. TARDEC Overview: Ground Vehicle Power and Mobility

    Science.gov (United States)

    2011-02-04

    Fuel & Water Distribution • Force Sustainment • Construction Equipment • Bridging • Assured Mobility Systems Robotics • TALON • PackBot • MARCbot...Equipment • Mechanical Countermine Equipment • Tactical Bridging Intelligent Ground Systems • Autonomous Robotics Systems • Safe Operations...Test Cell • Hybrid Electric Reconfigurable Moveable Integration Testbed (HERMIT) • Electro-chemical Analysis and Research Lab (EARL) • Battery Lab • Air

  10. Microtransactions in an Android Game

    OpenAIRE

    Kokkonen, Teemu

    2014-01-01

    The objective of this thesis is to explore the products sold within mobile applications and games, called in-app purchases or microtransactions. The thesis studies the history and nature of these microtransactions and examines their positive and negative effects on game design, as well as analyzes their usage in modern mobile games. To reinforce the research, a mobile game codenamed TownBuilder was developed alongside the thesis. The game paid attention to the designs explored in the earl...

  11. How it Works: Some Recent Developments in the Pursuit of Academic Excellence

    Science.gov (United States)

    1990-09-01

    parents as teachers project. Evaluation report and executive evaluation summary. ERIC Document, ED 264 954. Schaefer, Earl S. (1985). Maternal infancy...making, stress the importance of status distinctions, and lack a clear desire to offer emotional and authoritative support to teachers and staff, they... authoritarian structure, or inconsistent funding? However, emphasis should still be placed on the method for assessing the importance of any obstacle

  12. Fire, fuels, and restoration of ponderosa pine-Douglas-fir forests in the Rocky Mountains, USA

    OpenAIRE

    Baker, W. L.; Veblen, T. T.; Sherriff, R. L.

    2007-01-01

    Forest restoration in ponderosa pine and mixed ponderosa pine–Douglas fir forests in the US Rocky Mountains has been highly influenced by a historical model of frequent, low-severity surface fires developed for the ponderosa pine forests of the Southwestern USA. A restoration model, based on this low-severity fire model, focuses on thinning and prescribed burning to restore historical forest structure. However, in the US Rocky Mountains, research on fire history and forest structure, and earl...

  13. Strands of the future: France and the birth of electronica

    OpenAIRE

    Albiez, Sean

    2005-01-01

    The early history of 1970s electronic rock music, or electronica, often centres on the innovations of Brian Eno, Tangerine Dream and Kraftwerk, whose creative roots are identified as in avant-garde modernist and contemporary music (e.g. Luigi Russolo, Edgard Varese, John Cage, Karlheinz Stockhausen and Pierre Schaeffer). German, British and American artists have gained wide recognition for their roles in this history, but French artists who made important contributions to developments in earl...

  14. Nové trendy v internetové marketingové komunikaci - sociální síť Facebook

    OpenAIRE

    Eisenmann, Jan

    2008-01-01

    Theme of my bachelor thesis is "New trends in internet marketing communication -- social network Facebook". Theoretical part is focused on describing those new trends -- like viral marketing, Web 2.0 and it's major tools (social media, RSS, wikis, social networks). And also I try to set the shift from old to new media into context of wider economical changes. Important source of information were books and works of Mark Earls about "herd" substance of human behavior as well as Seth Godin's PUL...

  15. Annotated Bibliography of the Air Force Human Resources Laboratory Technical Reports - 1979.

    Science.gov (United States)

    1981-05-01

    Conli I1t’s ii t he earl ier st id% were pred icted as well as flte emipirical crimn site; hiowe’ve r. ill this stwail. [te resol riItei re iii ich...various combinations of *’anchor" item calibration sample size and equating same size. (l pages) 70 Donahue, K.E., Medellin , A., & Loup, K. Bibliography

  16. A 'blessed asylum' or a utopian vision : the viability of a Protestant nunnery in early nineteenth-century England

    OpenAIRE

    Collier, J

    2014-01-01

    In 1694, Mary Astell proposed the establishment of Protestant nunneries in England; in 1809, Helena Whitford reiterated the theme; yet, it was Lady Isabella King in 1816 who sought to put this radical idea into effect. A single, Irish, evangelically influenced gentlewoman, a younger daughter of the Earl of Kingston, she established the Ladies’ Association, a ‘conventual’ home for eighteen distressed gentlewomen at Bailbrook House in Bath in 1816, securing support for it from such influential ...

  17. Strategies and challenges for safe injection practice in developing countries

    OpenAIRE

    Gyawali, Sudesh; Rathore, Devendra Singh; Shankar, P Ravi; Kumar, KC Vikash

    2013-01-01

    Injection is one of the important health care procedures used globally to administer drugs. Its unsafe use can transmit various blood borne pathogens. This article aims to review the history and status of injection practices, its importance, interventions and the challenges for safe injection practice in developing countries. The history of injections started with the discovery of syringe in the early nineteenth century. Safe injection practice in developed countries was initiated in the earl...

  18. Advances in Applied Ceramics: Guest editorial

    OpenAIRE

    Hazell, P. J.

    2010-01-01

    The development, engineering, and testing of ceramic armour systems and materials has been carried out during the past 50 years and dates back to the pioneering work of M. L. Wilkins and his colleagues [1]. Arguably, the first indications that such armour would be ballistically efficient were seen much earlier than Wilkins when, in 1918 Maj Neville Monroe‐Hopkins found that a thin layer of enamel improved the ballistic performance of a thin steel plate [2]. Indeed, many earl...

  19. Air Force Health Study. An Epidemiologic Investigation of Health Effects in Air Force Personnel Following Exposure to Herbicides. Introduction, Background and Conclusions (Chapters 1-5, 18, 19)

    Science.gov (United States)

    1991-03-01

    Benvenuto, SAIC Lewis Pfister, SAIC Dung B. Phan, SAIC Vanessa K. Rocconi, SAIC Data processing and management support: Mary E. Carpentier, SAIC Carol A...Gregorio Faragoza, USAF Calvin E. Holloman, USAF Maricela Luna, USAF Earl A. Metts, USAF SSgt. Tracey H. Wilkinson, USAF3 Edward E. Zimmerman, USAF I I I I...Harris, NORC Cynthia Peters, NORC Jacques Van der Ven, NORC Belinda Willis, NORC I Logistical arrangements: Joyce A. Douglass, SAIC Jacqueline P. Kirk

  20. C-Mod Collaboration Informal Technical Progress Report

    International Nuclear Information System (INIS)

    Kenneth W. Gentle

    2007-01-01

    The aims of the collaboration have not changed. A specific list of tasks was agreed upon during the Fall of 2006 in preparation for the 2007 C-Mod campaign by Earl Marmar, Head of the Alcator Project, Kenneth Gentle, Principal Investigator, and William Rowan, Collaboration Coordinator with the facilitation of Adam Rosenberg (DOE grant monitor for the collaboration). The activities follow the list of tasks and are discussed in this progress report

  1. Can social microblogging be used to forecast intraday exchange rates?

    OpenAIRE

    Panagiotis Papaioannnou; Lucia Russo; George Papaioannou; Constantinos Siettos

    2013-01-01

    The Efficient Market Hypothesis (EMH) is widely accepted to hold true under certain assumptions. One of its implications is that the prediction of stock prices at least in the short run cannot outperform the random walk model. Yet, recently many studies stressing the psychological and social dimension of financial behavior have challenged the validity of the EMH. Towards this aim, over the last few years, internet-based communication platforms and search engines have been used to extract earl...

  2. A Nonparametric Multidimensional IRT Approach with Applications to Ability Estimation and Test Bias.

    Science.gov (United States)

    1988-04-01

    VA 22314 800 N. Quincy Street Attn: TC Arlington, VA 22217-5000 (12 Copies) Dr. Hans Crombag Dr. Stephen Dunbar University of Leyden Lindquist...CenterEducation Research Center for Measurement Boerhaavelaan 2 University of Iowa 2334 EN Leyden Iowa City, IA 52242 The NETHERLANDS Dr. James A. Earles Mr...William Montague Naval Air Station NPRDC Code 13 Pensacola, FL 32508 San Diego, CA 92152-6800 Dr. Gary Marco Ms. Kathleen Moreno Stop 31-E Navy Personnel R

  3. A Comparison of the Effects of Random Versus Fixed Order of Item Presentation Via the Computer

    Science.gov (United States)

    1989-02-01

    Copies) Dr. Hans Crombag Dr. Stephen Dunbar University of Leyden Lindquist Center Education Research Center for Measurement Boerhaavelaan 2 University of...Iowa 2334 EN Leyden Iowa City, IA 52242 The NETHERLANDS Dr. James A. Earles Dr. Timothy Davey Air Force Human Resources Lab Educational Testing...Montague 4401 Ford Avenue NPRDC Code 13 P.O. Box 16268 San Diego, CA 92152-6800 Alexandria, VA 22302-0268 Ms. Kathleen Moreno Dr..William L. Maloy

  4. Asymptotic Normality of Poly-T Densities with Bayesian Applications.

    Science.gov (United States)

    1987-10-01

    Quincy Street University of Iowa Arlington, VA 22217-5000 Iowa City, IA 52242 Dr. Hans Crombag Dr. James A. Earles University of Leyden Air Force Human...Resources Lab Education Research Center Brooks AFB, TX 78235 Boerhaavelaan 2 2334 EN Leyden Dr. Kent Eaton The NETHERLANDS Army Research Institute...William L. Maloy San Diego, CA 92152-6800 Chief of Naval Education and Training Ms. Kathleen Moreno Naval Air Station Navy Personnel R&D Center Pensacola

  5. The Coast Artillery Journal. Volume 79, Number 4, July-August 1936

    Science.gov (United States)

    1936-08-01

    to play, and to re- gard manhood as something to be acquired in the nebulous future. Comes a new face to the ROTC; its owner grins a friendly grin...Department Artillery Officer COLONEL LEWIS TURTLE , CA.C. Fort Amador COLONEL EARLE D’A. PEARCE 4thCA. (AA) F011 Sherman COLONEL WILLIAM M. CoLVIN 1stCA. Fort

  6. Mitochondrial Genomes of Kinorhyncha: trnM Duplication and New Gene Orders within Animals

    OpenAIRE

    Popova, Olga V.; Mikhailov, Kirill V.; Nikitin, Mikhail A.; Logacheva, Maria D.; Penin, Aleksey A.; Muntyan, Maria S.; Kedrova, Olga S.; Petrov, Nikolai B.; Panchin, Yuri V.; Aleoshin, Vladimir V.

    2016-01-01

    Many features of mitochondrial genomes of animals, such as patterns of gene arrangement, nucleotide content and substitution rate variation are extensively used in evolutionary and phylogenetic studies. Nearly 6,000 mitochondrial genomes of animals have already been sequenced, covering the majority of animal phyla. One of the groups that escaped mitogenome sequencing is phylum Kinorhyncha-an isolated taxon of microscopic worm-like ecdysozoans. The kinorhynchs are thought to be one of the earl...

  7. Combat Operations in Mountainous Terrain: Are United States Army Light Infantry Divisions Preparing Properly?

    Science.gov (United States)

    1987-06-05

    Mountain Division, Charles Hauptman, Comeany I. 97th Mountain Infantry Regiment by CPT George Earle, and PFC Hugh Graves (1945), and 10th Mountain...training in this country is believed to depend primarily ’Albert H. Jackman , "The Tenth Mountain Division, A Successful Experiment," The Algine Journal...44-48. Houston, Charles S., Dr. "Altitude Sickness and the Army," 112zard. 2d Qtr 1986: n.p. Jackman , Albert H. "The Tenth Mountain Division, A

  8. Reproductive and Metabolic Consequences of the Polycystic Ovarian Syndrome

    OpenAIRE

    Hudecova, Miriam

    2010-01-01

    Polycystic ovary syndrome (PCOS) is a complex clinical condition characterized by hyperandrogenism and chronic oligo/anovulation. Infrequent ovulation and metabolic alterations in women with PCOS are associated with subfertility and probably increased miscarriage rates compared with normal fertile women. The overall risk of developing type 2 diabetes and impaired glucose tolerance (IGT) is three- to sevenfold higher in PCOS women, and the onset of glucose intolerance seems to occur at an earl...

  9. Proceedings of Damping 󈨟, 13-15 February 1991, San Diego, California; Volume 1 (Pages AAC-1 through DCC-19)

    Science.gov (United States)

    1991-08-01

    SUPPLEMENTARY NOTATION Pages AAC-1 through DCC-19 17. COSATI CODES FIELD GROUP SU8 -GROUP 18. SUBJECT TERMS (Continue on reverse if necessary and...Direct Complex Stiffness Method Bradley R. Allen and Earl Pinson Direct Measurement of the Dynamic Material Properties of Polymers EB A for Low...half of the members are in nonmetallic industries ( many are in polymer industries ) and belong to the maker’s side of damping materials. About 35

  10. Squirrels With Scissors

    DEFF Research Database (Denmark)

    Skjerning, Halfdan; Clemmensen, Louise Thorsø

    2016-01-01

    Reviews the film Me and Earl and the Dying Girl (2015) directed by Alfonso Gomez-Rejon (2015). The film portrays the development of a friendship between three young people, one of them newly diagnosed with cancer. The film is a humorous declaration of love and the power of friendship. It is about...... meaning in a meaningless situation by selflessly giving to another person in ways that we all can give. (PsycINFO Database Record (c) 2016 APA, all rights reserved)...

  11. USSR and Eastern Europe Scientific Abstracts, Biomedical and Behavioral Sciences, Number 68

    Science.gov (United States)

    1977-04-13

    different protein fractions. In addition, the kinetics of the effect of a permanent magnetic field on solutions of bovine serum albumin was...virus with Earle’s solution, pH 8.2, Hottinger’s bouillon with 10% bovine serum pH 8.4 or 0.5 M phosphate buffer pH 8.2; and virological examination of...hepatitis, nephritis, mastitis et lymphonodulitis lymphonodulorum supramammarium, hyperplasia substantiae lymphoreticularis of the spleen and other lymph

  12. The CI-Flow Project: A System for Total Water Level Prediction from the Summit to the Sea

    Science.gov (United States)

    2011-11-01

    round and may be applied to all types of coastal storms , including intense cool- season extratropical cyclones (i.e., nor’easters). In addition...associated with waves, tides, storm surge, rivers, and rainfall, including interactions at the tidal/surge interface Within this project, Cl-FLOW addresses...presented for Hurricane Isabel (2003), Hurricane Earl (20I0), and Tropical Storm Nicole (2010) for the Tar -Pamlico and Neuse River basins of North

  13. Assessment of Assembling Objects (AO) for Improving Predictive Performance of the Armed Forces Qualification Test

    Science.gov (United States)

    2011-04-01

    Willis, 2000; Malinowski , 2001; Weiss, Kemmler, Deisenhammer, Fleischhacker, & Delazer, 2003; Wise, Welsh, Grafton, Foley, Earles, Sawin, & Divgi, 1992... Malinowski , 2001; Weiss et al., 2003; Wise et al., 1992). For example, Held, Alderton, Foley, and Segall (1993) found that men scored higher than women on...cognitive abilities across the adult life span. Aging, Neuropsychology, and Cognition, 7 (1), 32-53. Malinowski , J. (2001). Mental rotation and

  14. Aquatic Plant Control Research Program. Large-Scale Operations Management Test (LSOMT) of Insects and Pathogens for Control of Waterhyacinth in Louisiana. Volume 1. Results for 1979-1981.

    Science.gov (United States)

    1985-01-01

    and cucumber produced no evidence of disease symptoms. Cercospora rodmanii produced disease symptoms on only two varieties of lettuce in field tests...1978). He concluded that waterhyacinth is successful in eliminating water- lettuce because the larger leaves of waterhyacinth give it a competitive...adapted for 40 entomophily, pollination by insects has rarely been observed and self- pollination is the general rule (Penfound and Earle 1948). 32

  15. The Analysis of Cyanide and Its Breakdown Products in Biological Samples

    Science.gov (United States)

    2010-01-01

    Biological sampleb Speciesc CN Minutes-hours Some in a few species Low Blood, urine, saliva, tissue, expired air, rumen Human, fish, cow, mouse, rat...higher content in the left ventricle of fire victims. Journal of Chromatography 490 (1989):319–327. 96. R. H. Cardozo and I. S. Edelman, The volume of...Hagedorn, and R. Schulz, Development of a method for determination of cyanide concentrations in serum and rumen fluid of cattle. American Journal of

  16. Behavioral Ecology of Deep Diving Odontocetes in The Bahamas

    Science.gov (United States)

    2015-10-19

    have the most fluid social structure, though some dyadic bonds were suggested by similar persistent organic pollutant concentrations (which...surface, and are thought to have a communicative function (Schulz et al. 2008, Watkins and Schevill 1977, Weilgart and Whitehead 1993). Coda clicks and...species, with an average error radius of 3.5 km. Although this species surfaces regularly and tags therefore potentially could communicate frequently

  17. Genius loci jako estetický problém

    OpenAIRE

    Křížová, Lucie

    2016-01-01

    (in English): Diploma thesis Genius loci as an aesthetic problem is addressed by defining the concept of genius loci and exploring its aesthetic implications and parallels. After clarification of the ontological nature of this phenomenon its commonalities will be monitored with selected concepts of environmental philosophy and aesthetics, especially the aesthetic dimension of the environmental experience. Publications of Christian Norberg-Schulz and David E. Cooper are used as a starting mate...

  18. Anterior cruciate ligament reconstruction using bone plug-free quadriceps tendon autograft: intermediate-term clinical outcome after 24–36 months

    OpenAIRE

    Schulz AP; Lange V; Gille J; Voigt C; Fröhlich S; Stuhr M; Jürgens C

    2013-01-01

    Arndt P Schulz,1 Vivien Lange,2 Justus Gille,1 Christine Voigt,3 Susanne Fröhlich,4 Markus Stuhr,1 Christian Jürgens5 1Department of Orthopedics, Trauma, and Sports Medicine, University Hospital Lübeck, Lübeck, Germany; 2Department of Rehabilitation, Sana Regio Klinikum, Wedel, Germany; 3Department of Sports Medicine and Arthroscopy, Diakoniekrankenhaus Friederikenstift, Hannover, Germany; 4Department of Orthopedics, University of Rostock, Rostock, Germany;...

  19. Quantifying Entrepreneurial Networks: Data Collection in Addis Ababa, Ethiopia

    Science.gov (United States)

    2013-06-10

    to meet with the country manager for Schulze Global Investments (SGI), an emerging markets private equity firm. I had been introduced to Ms...member of the mirt team who has developed an interest in photography into a thriving business focusing on assisting firms with marketing and...bring in revenue. The branding business has now taken off and he has four employees and his clients include Pepsi . I also had the opportunity to eat

  20. Publicity, news content, and cultural debate

    DEFF Research Database (Denmark)

    Nørgaard Kristensen, Nete; From, Unni

    2015-01-01

    Taking our point of departure in mediatization theory (Hjarvard, 2013; Lundby, 2009; Schulz, 2004), we analyse the interwoven communicative forms of the film industry and the printed press as they are expressed in the coverage of three blockbusters in Danish newspapers – Ben-Hur (1959/62); Batman...... stimulate socio-cultural debate, at the same time as the portrayal of blockbuster movie events and their directors and actors at-tracts media audiences, serving as entertainment, service as well as enlightenment....

  1. Europe Report, Science and Technology.

    Science.gov (United States)

    1986-09-29

    MICROELECTRONICS Italian SGS President: Survival Strategies for Small Firms (Rudolf Schulze; VDI NACHRICHTEN , 11 Jul 86) 47 SCIENTIFIC AND INDUSTRIAL POLICY...29 September 1986 WEST EUROPE/^OtoEIECTRONICS ITALIAN SGS PRESIDENT: SURVIVAL STRATEGIES FOR SMALL FIRMS Duesseldorf VDI NACHRICHTEN in German...for Europe," first paragraph is VDI NACHRICHTEN introduction] [Text] Duesseldorf, 11 Jul 86—Japanese producers are in the process of taking over the

  2. Tribological approach to study polishing of road surface under traffic

    OpenAIRE

    KANE, Malal; DO, Minh Tan

    2007-01-01

    The polishing phenomenon of road pavements under the vehicle traffic constitutes the main mechanism inherent to the loss of skid resistance over time. A better understanding of this phenomenon would allow an improvement of road safety. This study comprises a review of laboratory test and a model simulating the polishing of road surfaces. The laboratory test uses a polishing machine so called 'Wehner-Schulze' which can reproduce the evolution of the road texture from specimens taken directly f...

  3. An overview of Suctorian ciliates (Ciliophora, Suctorea) as epibionts of halacarid mites (Acari, Halacaridae)

    Digital Repository Service at National Institute of Oceanography (India)

    Dovgal, I.; Chatterjee, T.; Ingole, B.S.

    Subclass Exogenia Collin Order Metacinetida Jankowski Family Paracinetidae Jankowski Limnoricus ceter Jankowski, 1981 (Fig. 1–3) Diagnosis: Marine commensal, loricate, suctorian ciliate with stalk delimited from posterior margin of lorica. Both lorica...–11) =Thecacineta halacari Schulz, 1933 DOVGAL ET AL.62 · Zootaxa 1810 © 2008 Magnolia Press =Lissacineta allgeni Jankowski, 1981, syn. n. =Thecacineta allgeni (Jankowski, 1981), syn. n. Diagnosis: Marine suctorians with stylotheca. Cell body, slightly...

  4. Intermetallic Matrix Composites 3 Symposium Held in San Francisco, California on April 4 - 6, 1994. Materials Research Society Symposium Proceedings. Volume 350

    Science.gov (United States)

    1994-04-06

    1992). 17 M.G. Mendiratta, J.J. Lewandowski and D.M. Dimiduk, Metal. Trans., f2A. 1573 (1991). 18. F. Dave , A.G. Evans, G.R. Odette, R. Mehrabian, M.L...S. C. Ur and M. Dollar, in (Proc. 2nd Int. Conf. Struct. Appl. Mech. Alloying. Vancouver. Canada, 1993) pp. 291-296. 6. P. A. Zielinski . R. Schulz, S

  5. Micro-cultural differences in Switzerland: The effectiveness of targeted promotional messages in the field of organ donation

    OpenAIRE

    Dunkel, Anke; Schulz, Peter

    2012-01-01

    Public information campaigns have played an important role in increasing awareness of organ donation and the need for more organ donors. In a recent study, it was found that awareness and knowledge, regarding organ donation, represented only two of several factors in people’s decisions to engage in organ donation-related behaviors (Schulz et al., 2006). In addition, it was noted that the three main language groups in Switzerland differ substantially with respect to the influential factors ...

  6. Comparison of Four Skin Decontamination Procedures Using Reactive Skin Decontamination Lotion (RSDL) Following Cutaneous VX Exposure in Guinea Pigs

    Science.gov (United States)

    2016-01-01

    DC) product following cutaneous exposure to VX was affected by the DC procedure. Fur-clipped, male, unanesthetized guinea pigs were used as subjects...RSDL) Following Cutaneous VX Exposure in Guinea Pigs Irwin Koplovitz Susan Schulz Julia Morgan Robert Reed Edward Clarkson C. Gary Hurst...Decontamination Procedures Using Reactive Skin 5a. CONTRACT NUMBER Decontamination Lotion (RSDL) Following Cutaneous VX Exposure in Guinea Pigs 5b

  7. The History of the North Pacific Division U.S. Army Corps of Engineers 1888 to 1965

    Science.gov (United States)

    1969-01-01

    jetties at the entrance to Humboldt Bay, California. On March 2, 1907, he was retired from active service by virtue of his having reached the statutory...school commandant and post commander Schulz ,gave personal attention to the uncovering of the foundation ruins of the historic Belvoir Mansion , which...the Belvoir Mansion was the home of Colonel William Fairfax, who was the original owner of the Belvoir estate. He was a friend of George Washington

  8. Beginning of the End: The Leadership of SS Obersturmbannfuehrer Jochen Peiper

    Science.gov (United States)

    2004-06-17

    of Rudolf Lehmann and Ralf Tiemann on the Leibstandarte are based on the Bundesarchiven (National Archives) in Koblenz and Freiburg in Germany...Hans Schmidt, Paul Hausser, Richard Schulze-Kossens, Rudolf Lehmann, and Ralf Tiemann. Some German sources are at odds with American sources, but that...or a constitution. Among the men who set up the first military training for the Waffen-SS were Felix Steiner and Cassius Freiherr (Baron) von

  9. Large Atmospheric Computation on the Earth Simulator: The LACES Project

    Directory of Open Access Journals (Sweden)

    Michel Desgagné

    2006-01-01

    Full Text Available The Large Atmospheric Computation on the Earth Simulator (LACES project is a joint initiative between Canadian and Japanese meteorological services and academic institutions that focuses on the high resolution simulation of Hurricane Earl (1998. The unique aspect of this effort is the extent of the computational domain, which covers all of North America and Europe with a grid spacing of 1 km. The Canadian Mesoscale Compressible Community (MC2 model is shown to parallelize effectively on the Japanese Earth Simulator (ES supercomputer; however, even using the extensive computing resources of the ES Center (ESC, the full simulation for the majority of Hurricane Earl's lifecycle takes over eight days to perform and produces over 5.2 TB of raw data. Preliminary diagnostics show that the results of the LACES simulation for the tropical stage of Hurricane Earl's lifecycle compare well with available observations for the storm. Further studies involving advanced diagnostics have commenced, taking advantage of the uniquely large spatial extent of the high resolution LACES simulation to investigate multiscale interactions in the hurricane and its environment. It is hoped that these studies will enhance our understanding of processes occurring within the hurricane and between the hurricane and its planetary-scale environment.

  10. Scale Issues Related to the Accuracy Assessment of Land Use/Land Cover Maps Produced Using Multi-Resolution Data: Comments on “The Improvement of Land Cover Classification by Thermal Remote Sensing”. Remote Sens. 2015, 7(7, 8368–8390

    Directory of Open Access Journals (Sweden)

    Brian A. Johnson

    2015-10-01

    Full Text Available Much remote sensing (RS research focuses on fusing, i.e., combining, multi-resolution/multi-sensor imagery for land use/land cover (LULC classification. In relation to this topic, Sun and Schulz [1] recently found that a combination of visible-to-near infrared (VNIR; 30 m spatial resolution and thermal infrared (TIR; 100–120 m spatial resolution Landsat data led to more accurate LULC classification. They also found that using multi-temporal TIR data alone for classification resulted in comparable (and in some cases higher classification accuracies to the use of multi-temporal VNIR data, which contrasts with the findings of other recent research [2]. This discrepancy, and the generally very high LULC accuracies achieved by Sun and Schulz (up to 99.2% overall accuracy for a combined VNIR/TIR classification result, can likely be explained by their use of an accuracy assessment procedure which does not take into account the multi-resolution nature of the data. Sun and Schulz used 10-fold cross-validation for accuracy assessment, which is not necessarily inappropriate for RS accuracy assessment in general. However, here it is shown that the typical pixel-based cross-validation approach results in non-independent training and validation data sets when the lower spatial resolution TIR images are used for classification, which causes classification accuracy to be overestimated.

  11. The contribution of thermal radiation to the thermal conductivity of porous UO2

    International Nuclear Information System (INIS)

    Bakker, K.; Kwast, H.; Cordfunke, E.H.P.

    1995-01-01

    The influence of cylindrical, spherical and ellipsoidal inclusions on the overall thermal conductivity was computed with the finite element technique. The results of these calculations were compared with equations that describe the effect of inclusions on the overall thermal conductivity. The analytical equation of Schulz [B. Schulz, KfK-1988 (1974)] that describes the effect of inclusions on the overall thermal conductivity is in good agreement with the results of the finite element computations. This good agreement shows that among a variety of porosity correction formulas, the equation of Schulz gives the best description of the effect of inclusions on the overall thermal conductivity. This equation and the results of finite element calculations allow us to compute the contribution of radiation to the overall thermal conductivity of UO 2 with oblate ellipsoidal porosity. The present radiation calculations show that Hayes and Peddicord [S.L. Hayes and K.L. Peddicord, J. Nucl. Mater. 202 (1993) 87] overestimated the contribution of thermal radiation to the thermal conductivity. ((orig.))

  12. Platinum stable isotopes in ferromanganese crust and nodules

    Science.gov (United States)

    Corcoran, Loretta; Seward, Terry; Handler, Monica R.

    2015-04-01

    Hydrogenetic ferromanganese (Fe-Mn) crust and nodules are slow-growing chemical sediments that form by direct precipitation from seawater, resulting in a record of changing seawater chemistry. These sediments are the primary sink for platinum in the modern oxic marine environment, hosting well-documented enrichments over other platinum-group elements (PGEs): the Pt anomaly [1]. Platinum is a non-bio-essential, highly siderophile, transition metal with six stable isotopes (190Pt, 192Pt, 194Pt, 195Pt, 196Pt, and 198Pt) with several oxidation states (Pt0, Pt2+ and Pt4+). Platinum is generally considered to exist in the hydrosphere as Pt2+ although its behaviour in the marine environment is poorly constrained, and Pt4+may also be present. Variations in ocean redox state, together with changes in source fluxes to the oceans, may therefore lead to small variations (Leaching experiments conducted on platinum rich terrestrial materials underwent platinum stable isotopic measurement as an analogue for the Pt isotopic fractionation associated with continental weathering. [1] Hodge, V.F. et al. (1985) Earth and Planetary Science Letters, 72, 158-162. [2] Creech, J. et al. (2013) Journal of Analytical Atomic Spectrometry, 28. 853-865.

  13. Compression-cuticle relationship of seed ferns: Insights from liquid-solid states FTIR (Late Palaeozoic-Early Mesozoic, Canada-Spain-Argentina)

    Science.gov (United States)

    Zodrow, E.L.; D'Angelo, J. A.; Mastalerz, Maria; Keefe, D.

    2009-01-01

    Cuticles have been macerated from suitably preserved compressed fossil foliage by Schulze's process for the past 150 years, whereas the physical-biochemical relationship between the "coalified layer" with preserved cuticle as a unit has hardly been investigated, although they provide complementary information. This relationship is conceptualized by an analogue model of the anatomy of an extant leaf: "vitrinite (mesophyll) + cuticle (biomacropolymer) = compression". Alkaline solutions from Schulze's process as a proxy for the vitrinite, are studied by means of liquid-solid states Fourier transform infrared spectroscopy (FTIR). In addition, cuticle-free coalified layers and fossilized cuticles of seed ferns mainly from Canada, Spain and Argentina of Late Pennsylvanian-Late Triassic age are included in the study sample. Infrared data of cuticle and alkaline solutions differ which is primarily contingent on the mesophyll +biomacropolymer characteristics. The compression records two pathways of organic matter transformation. One is the vitrinized component that reflects the diagenetic-post-diagenetic coalification history parallel with the evolution of the associated coal seam. The other is the cuticle that reflects the sum-total of evolutionary pathway of the biomacropolymer, its monomeric, or polymeric fragmentation, though factors promoting preservation include entombing clay minerals and lower pH conditions. Caution is advised when interpreting liquid-state-based FTIR data, as some IR signals may have resulted from the interaction of Schulze's process with the cuticular biochemistry. A biochemical-study course for taphonomy is suggested, as fossilized cuticles, cuticle-free coalified layers, and compressions are responses to shared physicogeochemical factors. ?? 2009 Elsevier B.V. All rights reserved.

  14. Compression-cuticle relationship of seed ferns: Insights from liquid-solid states FTIR (Late Palaeozoic-Early Mesozoic, Canada-Spain-Argentina)

    Energy Technology Data Exchange (ETDEWEB)

    Zodrow, Erwin L. [Palaeobotanical Laboratory, Cape Breton University, Sydney, Nova Scotia (Canada); D' Angelo, Jose A. [Instituto Argentino de Nivologia, Glaciologia y Ciencias Ambientales (IANIGLA), CCT-CONICET-Mendoza, Avda. Ruiz Leal s/n Parque Gral. San Martin (5500) Mendoza (Argentina); Area de Quimica, Instituto de Ciencias Basicas, Universidad Nacional de Cuyo, Centro Universitario - M5502JMA - Mendoza (Argentina); Mastalerz, Maria [Indiana Geological Survey, Indiana University, 611 North Walnut Grove, Bloomington, IN 47405-2208 (United States); Keefe, Dale [Molecular Spectroscopy Research Laboratory, Department of Chemistry, Cape Breton University, Sydney, Nova Scotia (Canada)

    2009-08-01

    Cuticles have been macerated from suitably preserved compressed fossil foliage by Schulze's process for the past 150 years, whereas the physical-biochemical relationship between the ''coalified layer'' with preserved cuticle as a unit has hardly been investigated, although they provide complementary information. This relationship is conceptualized by an analogue model of the anatomy of an extant leaf: ''vitrinite (mesophyll) + cuticle (biomacropolymer) = compression''. Alkaline solutions from Schulze's process as a proxy for the vitrinite, are studied by means of liquid-solid states Fourier transform infrared spectroscopy (FTIR). In addition, cuticle-free coalified layers and fossilized cuticles of seed ferns mainly from Canada, Spain and Argentina of Late Pennsylvanian-Late Triassic age are included in the study sample. Infrared data of cuticle and alkaline solutions differ which is primarily contingent on the mesophyll +biomacropolymer characteristics. The compression records two pathways of organic matter transformation. One is the vitrinized component that reflects the diagenetic-post-diagenetic coalification history parallel with the evolution of the associated coal seam. The other is the cuticle that reflects the sum-total of evolutionary pathway of the biomacropolymer, its monomeric, or polymeric fragmentation, though factors promoting preservation include entombing clay minerals and lower pH conditions. Caution is advised when interpreting liquid-state-based FTIR data, as some IR signals may have resulted from the interaction of Schulze's process with the cuticular biochemistry. A biochemical-study course for taphonomy is suggested, as fossilized cuticles, cuticle-free coalified layers, and compressions are responses to shared physicogeochemical factors. (author)

  15. Retinoid quantification by HPLC/MS(n)

    Science.gov (United States)

    McCaffery, Peter; Evans, James; Koul, Omanand; Volpert, Amy; Reid, Kevin; Ullman, M. David

    2002-01-01

    Retinoic acid (RA) mediates most of the biological effects of vitamin A that are essential for vertebrate survival. It acts through binding to receptors that belong to the nuclear receptor transcription factor superfamily (Mangelsdorf et al. 1994). It is also a highly potent vertebrate teratogen. To determine the function and effects of endogenous and exogenous RA, it is important to have a highly specific, sensitive, accurate, and precise analytical procedure. Current analyses of RA and other retinoids are labor intensive, of poor sensitivity, have limited specificity, or require compatibility with RA reporter cell lines (Chen et al. 1995. BIOCHEM: Pharmacol. 50: 1257-1264; Creech Kraft et al. 1994. BIOCHEM: J. 301: 111-119; Lanvers et al. 1996. J. Chromatogr. B Biomed. Appl. 685: 233-240; Maden et al. 1998. DEVELOPMENT: 125: 4133-4144; Wagner et al. 1992. DEVELOPMENT: 116: 55-66). This paper describes an HPLC/mass spectrometry/mass spectrometry product ion scan (HPLC/MS(n)) procedure for the analysis of retinoids that employs atmospheric pressure chemical ionization MS. The retinoids are separated by normal-phase column chromatography with a linear hexane-isopropanol-dioxane gradient. Each retinoid is detected by a unique series of MS(n) functions set at optimal collision-induced dissociation energy (30% to 32%) for all MS(n) steps. The scan events are divided into three segments, based on HPLC elution order, to maximize the mass spectrometer duty cycle. The all-trans, 9-cis, and 13-cis RA isomers are separated, if desired, by an isocratic hexane-dioxane-isopropanol mobile phase. This paper describes an HPLC/MS(n) procedure possessing high sensitivity and specificity for retinoids.

  16. Tracing metal-silicate segregation and late veneer in the Earth and the ureilite parent body with palladium stable isotopes

    Science.gov (United States)

    Creech, J. B.; Moynier, F.; Bizzarro, M.

    2017-11-01

    Stable isotope studies of highly siderophile elements (HSE) have the potential to yield valuable insights into a range of geological processes. In particular, the strong partitioning of these elements into metal over silicates may lead to stable isotope fractionation during metal-silicate segregation, making them sensitive tracers of planetary differentiation processes. We present the first techniques for the precise determination of palladium stable isotopes by MC-ICPMS using a 106Pd-110Pd double-spike to correct for instrumental mass fractionation. Results are expressed as the per mil (‰) difference in the 106Pd/105Pd ratio (δ106Pd) relative to an in-house solution standard (Pd_IPGP) in the absence of a certified Pd isotopic standard. Repeated analyses of the Pd isotopic composition of the chondrite Allende demonstrate the external reproducibility of the technique of ±0.032‰ on δ106Pd. Using these techniques, we have analysed Pd stable isotopes from a range of terrestrial and extraterrestrial samples. We find that chondrites define a mean δ106Pdchondrite = -0.19 ± 0.05‰. Ureilites reveal a weak trend towards heavier δ106Pd with decreasing Pd content, similar to recent findings based on Pt stable isotopes (Creech et al., 2017), although fractionation of Pd isotopes is significantly less than for Pt, possibly related to its weaker metal-silicate partitioning behaviour and the limited field shift effect. Terrestrial mantle samples have a mean δ106Pdmantle = -0.182 ± 0.130‰, which is consistent with a late-veneer of chondritic material after core formation.

  17. The Great Famine in Nationalist and Land League propaganda 1879-1882

    OpenAIRE

    RYNNE, Frank

    2015-01-01

    Introduction In the late 1870s news of famines in India and China appeared continuously in Irish newspapers. The reporting of these famines in Ireland sometimes directly alluded to Ireland’s Great Famine with The Nation reporting: A great deal has been said about over-population in India, just as there has been talk about overpopulation in Ireland, and the Earl of Beaconsfield, or some other political leader, may yet call for three cheers for famine for having removed "the redundant people."...

  18. The garden as a laboratory: the role of domestic gardens as places of scientific exploration in the long 18th century.

    Science.gov (United States)

    Hickman, Clare

    2014-06-01

    Eighteenth-century gardens have traditionally been viewed as spaces designed for leisure, and as representations of political status, power and taste. In contrast, this paper will explore the concept that gardens in this period could be seen as dynamic spaces where scientific experiment and medical practice could occur. Two examples have been explored in the pilot study which has led to this paper - the designed landscapes associated with John Hunter's Earl's Court residence, in London, and the garden at Edward Jenner's house in Berkeley, Gloucestershire. Garden history methodologies have been implemented in order to consider the extent to which these domestic gardens can be viewed as experimental spaces.

  19. Successful Separationists in a Unity Fan Society: Al-Hirak Al-Janubi Social Movement in the Republic of Yemen

    Science.gov (United States)

    2013-12-01

    Al-Janubi’s popularity and motivations. Jennifer Earl uses three key typology dimensions to categorize repression of a given movement. Those...use Earl’s typology of repression as an attempt to understand the effects on the relationship between the government and Al-Hirak Al-Janubi in Yemen...let him invest in Aden; then he would sell him the sea area to dump rocks onto it to make it suitable as a tourist site. Finally, he would sell him

  20. Signature of terrestrial influence on nitrogen isotopic composition of suspended particulate

    Digital Repository Service at National Institute of Oceanography (India)

    Kumar, S.; Ramesh, R.; Sheshshayee, M.S.; Sardessai, S.; Patel, P.P.

    du ring their res i dence in th eir parent bodies. Cosmogenic records i n dicate a larg e size ( greaterequal 1 m) for the Kendrapara meteoroid that has spent ~5 million years in interplanetary space follo w ing its ejection from its parent... of these objects provide us insight into the processes governing the very earl y evol u tion of the solar system and also the mode of its probable origin 1 . Meteorite studies in general provide clues to u n derstand the evolution of their parent bodies...

  1. Customer Satisfaction & Loyalty in the Singapore Retail Fuel Market

    OpenAIRE

    Koh, See Yong

    2009-01-01

    Where are all the customers? If your competitors have got them, then it’s a bad news. The good news is that you can win them back or attract new ones. This may sound simple and easy. However, the starkest challenge facing business today is customer scarcity where they are too many sellers for too few buyers. According to an article from Harvard Business Review, Frederick Reichheld and Earl Sasser (2000) explained that there is a high cost of losing customers. This includes reduce profitab...

  2. Deer forests, game shooting and landed estates in the South West of Ireland, 1840 - 1970

    OpenAIRE

    Ryan, John M. (Sean)

    2001-01-01

    This thesis is concentrated on the historical aspects of the elitist field sports of deer stalking and game shooting, as practiced by four Irish landed ascendancy families in the south west of Ireland. Four great estates were selected for study. Two of these were, by Irish standards, very large: the Kenmare estate of over 136,000 acres in the ownership of the Roman Catholic Earls of Kenmare, and the Herbert estate of over 44,000 acres in the ownership of the Protestant Herbert family. The oth...

  3. A Colonial Conundrum: Boy with Sulphur-Crested Cockatoo

    Directory of Open Access Journals (Sweden)

    Elisabeth Findlay

    2008-12-01

    Full Text Available This paper presents a detailed analysis of the perplexing painting Boy with Sulphur-Crested Cockatoo. Unfortunately, there is little information on the provenance of the portrait, including the identity of the artist, sitter and patron. It will be argued that it is the work of Augustus Earle and that it is a portrait of Daniel Cooper II and was commissioned by his uncle, also named Daniel Cooper. The aim of this article is to start to unravel the ambiguities of the image, and I suggest that the painting is a strong statement on the rights of freed convicts in Australian colonial society

  4. Index of Air Weather Service Technical Publications. Headquarters AWS and Subordinate Units.

    Science.gov (United States)

    1982-07-01

    llp (ATI-98239). 105-77 "Hurricanes of 1950: Narrative History of Each Storm and Comments on Hurricane Reconnaissance," July 1951, 90p (ATI-110565...Solar Flare Videometer," by Paul E. Tallant, pp. 92-109. "The Use of Ground Level Neutron Monitors in a Real Time Solar Proton Monitoring Network," by M...8-12p ’Window’ Radiation over Indonesia and Malaysia ," by Earl S. Merritt, pp. 245-253. "Short Range, Subsynoptic Surface Weather Prediction," by

  5. Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994

    International Nuclear Information System (INIS)

    1995-07-01

    Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera

  6. In vitro degradation of ZM21 magnesium alloy in simulated body fluids.

    Science.gov (United States)

    Witecka, Agnieszka; Bogucka, Aleksandra; Yamamoto, Akiko; Máthis, Kristián; Krajňák, Tomáš; Jaroszewicz, Jakub; Święszkowski, Wojciech

    2016-08-01

    In vitro degradation behavior of squeeze cast (CAST) and equal channel angular pressed (ECAP) ZM21 magnesium alloy (2.0wt% Zn-0.98wt% Mn) was studied using immersion tests up to 4w in three different biological environments. Hanks' Balanced Salt Solution (Hanks), Earle's Balanced Salt Solution (Earle) and Eagle minimum essential medium supplemented with 10% (v/v) fetal bovine serum (E-MEM+10% FBS) were used to investigate the effect of carbonate buffer system, organic compounds and material processing on the degradation behavior of the ZM21 alloy samples. Corrosion rate of the samples was evaluated by their Mg(2+) ion release, weight loss and volume loss. In the first 24h, the corrosion rate sequence of the CAST samples was as following: Hanks>E-MEM+10% FBS>Earle. However, in longer immersion periods, the corrosion rate sequence was Earle>E-MEM+10% FBS≥Hanks. Strong buffering effect provided by carbonate buffer system helped to maintain the pH avoiding drastic increase of the corrosion rate of ZM21 in the initial stage of immersion. Organic compounds also contributed to maintain the pH of the fluid. Moreover, they adsorbed on the sample surface and formed an additional barrier on the insoluble salt layer, which was effective to retard the corrosion of CAST samples. In case of ECAP, however, this effect was overcome by the occurrence of strong localized corrosion due to the lower pH of the medium. Corrosion of ECAP samples was much greater than that of CAST, especially in Hanks, due to higher sensitivity of ECAP to localized corrosion and the presence of Cl(-). The present work demonstrates the importance of using an appropriate solution for a reliable estimation of the degradation rate of Mg-base degradable implants in biological environments, and concludes that the most appropriate solution for this purpose is E-MEM+10% FBS, which has the closest chemical composition to human blood plasma. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Human radiation studies: Remembering the early years. Oral history of Dr. Nadine Foreman, M.D., August 19, 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-07-01

    Dr. Nadine Foreman was interviewed by representatives of the US DOE Office of Human Radiation Experiments (OHRE). Dr. Foreman was selected for interview because of the position she held at the University of California, San Francisco. Following a brief biographical sketch, Dr. Foreman describes her work with Dr. Mayo Soley using I-131 in treatment of hyperthyroidism, selection criteria for patients in the radioiodine project, work with Dr. Earl Miller, work at Highland Hospital, radioiodine treatment of diffuse toxic goiter (myxedema), the radiophosphorus and radioiodine programs with Dr. Bert Low-Beer, and treatment of polycythemia vera.

  8. Rho-ω interference in the reactions K-p→π+π-(Λ,Σ0) at 4.2 GeV/c

    International Nuclear Information System (INIS)

    Holmgren, S.O.; Aguilar-Benitez, M.; Cerrada, M.; Hemingway, R.J.; Losty, M.J.; Worden, R.P.; Jongejans, B.; Massaro, G.G.G.; Wolters, G.F.; Engelen, J.J.; Schotanus, D.J.; Walle, R.T. van de; Foster, B.; Lyons, L.; Wells, J.

    1977-01-01

    Rho-ω interference is studied in the reactions K - p→π + π - (Λ 0 ,Σ) at 4.2 GeV/c using data from a high statistics experiment in the CERN 2m HBC. The phenomenon is analysed in terms of the conventional formalism as well as in terms of a new model for rho-ω interference proposed by Earles and Srivastava. Satisfactory agreement with the data is found for both models. The rate of ω→2π obtained in the latter model is in agreement with the VMD (Vector Meson Dominance) prediction for ω→γ→rho→2π. (Auth.)

  9. Modern African, Asian, Latin American, and Middle Eastern Military History: A Bibliography of English-Language Books and Articles Published From 1960-2013

    Science.gov (United States)

    2014-03-01

    in Sub-Saharan Africa: Some Evidence for 1967-85.” Journal of Peace Research XXXII 3 (August 1995): 331-343. Echenberg, Myron. “’Morts Pour la...Political Reform.” The Journal of Modern African Studies XXXII 1 (March 1994): 29-51. Howe, John. “Western Sahara: A War Zone.” Review of...Neglected Tragedy: The Return to War in Angola, 1992-3.” The Journal of Modern African Studies XXXII 1 (March 1994): 1-28. Phillips, Earl. “The Egba at

  10. Proceedings of a Hydrology and Hydraulics Workshop on Riverine Levee Freeboard Held in Monticello, Minnesota on 27-29 August 1991

    Science.gov (United States)

    1991-12-10

    Presented by Earl E. Eiker) Headquarters, U.S. Army Corps of Engineers ...................... 5 LEVEE FREEBOARD DEJA VU ALL OVER AGAIN (Paper 2) Brad...0~e a) . Plate PAPE 0 12 LEVEE FREEBOARD DEJA VU ALL OVER AGAIN by Brad Fowler 1 presented by Robert M. Daniel2 1. Introduction. It’s been now nearly... Deja Vu All Over Again (Bob Daniel, HQUSACE) 10:00 - 10:15 am Break 10:15 - 11:00 am Paper 3 FEMA Levee Accreditation Procedures (John Matticks, Asst

  11. Juxtaposing Cogadh Gáedel re Gallaib with Orkneyinga saga

    Directory of Open Access Journals (Sweden)

    Thomas A. DuBois

    2011-10-01

    Full Text Available The fields of Scandinavian studies and Celtic studies have reveled in the rich trove of vernacular literature preserved in medieval forms of Icelandic and Irish. The scholarly traditions within the fields, however, have hindered cross-cultural comparison, despite the fact that Irish and Scandinavians had abundant cultural contact and produced texts that at times refer to each other in detail. This paper explores the usefulness of comparing two often-marginalized works—the Irish Munster saga and royal panegyric, _Cogadh Gáedel re Gallaib_, and the history of the earls of Orkney known as _Orkneyinga saga_.

  12. Bayesian computation with R

    CERN Document Server

    Albert, Jim

    2009-01-01

    There has been a dramatic growth in the development and application of Bayesian inferential methods. Some of this growth is due to the availability of powerful simulation-based algorithms to summarize posterior distributions. There has been also a growing interest in the use of the system R for statistical analyses. R's open source nature, free availability, and large number of contributor packages have made R the software of choice for many statisticians in education and industry. Bayesian Computation with R introduces Bayesian modeling by the use of computation using the R language. The earl

  13. The International Symposium on Equatorial Aeronomy (10th) Held in Antalya, Turkey on May 17-23, 2000

    Science.gov (United States)

    2000-10-23

    P. ST.- MAURICE 2. 8:55-9:10 East-West Asymmetry in Type I Electrojet Conveners: S. Fukao and C. Haldoupis Echoes at Jicamarca, J. L. CHAU, D. T...Kudeki, S. Franke, J. Urbina, M. Larsen, D. mamoto, and S. Fukao. Hysell, J. Clemmons , G. Earle, R. Heelis, R. 6. 15:10-15:25 Large scale E-region...GPS/DMSP Ionization Gauges, J. H. CLEMMONS , R. F. Observations, and the Equatorial Region, J. Aarons, Pfaff, and M. F. Larsen. M. MENDILLO, and P

  14. Control and Health Monitoring of Variable Speed Wind Power Generation Systems; Period of Performance: 10 July 1997 - 10 July 2000

    Energy Technology Data Exchange (ETDEWEB)

    Song, Y. D.; Bikdash, M.; Schulz, M. J.

    2001-09-01

    This document reports accomplishments on variable speed control, furling analysis, and health monitoring of wind turbines. There are three parts, prepared by Song, Bikdash, and Schulz, respectively. The first part discusses variable-speed control of wind turbines, exploring a memory-based method for wind speed prediction and wind turbine control. The second part addresses the yaw dynamics of wind turbines, including modeling, analysis, and control. The third part of the report discusses new analytical techniques that were developed and tested to detect initial damage to prevent failures of wind turbine rotor blades.

  15. Sound & The Senses

    DEFF Research Database (Denmark)

    Schulze, Holger

    2012-01-01

    How are those sounds you hear right now technically generated and post-produced, how are they aesthetically conceptualized and how culturally dependant are they really? How is your ability to hear intertwined with all the other senses and their cultural, biographical and technological constructio...... over time? And how is listening and sounding a deeply social activity – constructing our way of living together in cities as well as in apartment houses? A radio feature with Jonathan Sterne, AGF a.k.a Antye Greie, Jens Gerrit Papenburg & Holger Schulze....

  16. Precipitation as driver of carbon fluxes in 11 African ecosystems

    CSIR Research Space (South Africa)

    Merbold, L

    2009-01-01

    Full Text Available ). Given the shortness of the record, the EC data were analysed across the network rather than longitudinally at sites, in order to under- stand the driving factors for ecosystem respiration and car- bon assimilation, and to reveal the different water... by Schulze et al. (1994) and the thick solid regression line shows the regression for the eleven African sites. (n=11) variability in the global terrestrial cycles of water and car- bon (Williams et al., 2007; Weber et al., 2009). More- over, all African...

  17. Open forum: Question and responses

    International Nuclear Information System (INIS)

    Schulze, R.H.; Krupa, S.; Shen, T.T.

    1993-01-01

    The question addressed in this section is: With the end of the Cold War and the exchange of information improving between East and West, what roles should government agencies and non-government organizations from developed countries play in assisting less developed countries in developing a stronger environmental protection program? Responses presented here were obtained from Richard H. Schulze (President of Trinity Consultants, Inc.), Sagar Krupa (Professor, Department of Plant Pathology, University of Minnesota), and Thomas T. Shen (Ph.D., D.AAEE, Retiree of the New York Department of Environmental Conservation)

  18. A non-commutative formula for the isotropic magneto-electric response

    International Nuclear Information System (INIS)

    Leung, Bryan; Prodan, Emil

    2013-01-01

    A non-commutative formula for the isotropic magneto-electric response of disordered insulators under magnetic fields is derived using the methods of non-commutative geometry. Our result follows from an explicit evaluation of the Ito derivative with respect to the magnetic field of the non-commutative formula for the electric polarization reported in Schulz-Baldes and Teufel (2012 arXiv:1201.4812v1). The quantization, topological invariance and connection to a second Chern number of the magneto-electric response are discussed in the context of three-dimensional, disordered, time-reversal or inversion symmetric topological insulators. (paper)

  19. Why Leadership Matters: Joint Task Force Planning with the Department of State

    Science.gov (United States)

    2013-12-10

    137. 12Ibid. 13Ibid., 192-195. 14Gabriel Marcella and General Frederick F. Woerner Jr., U.S. Army (Ret.), “The Road to War: The U.S – Panamanian...change the plan to accommodate the agreement brokered by President Carter. 43 39Donald E. Schulz and Gabriel Marcella , Reconciling the... Marcella , Gabriel, and General Frederick F. Woerner Jr., U.S. Army (Ret.). “The Road to War: The U.S—Panamanian Crisis, 1987–1989.” Draft article, 6 May 91

  20. Multi-Robot Systems in Military Domains (Les Systemes Multi-Robots Dans les Domaines Militaires)

    Science.gov (United States)

    2008-12-01

    IST-032 Middleware G-6 Object Request Brokers (ORBs) G-8 DCOM G-10 CORBA G-11 Java RMI G-14 Java RMI-IIOP G-16 Jini G-16 Comparison... hibernating since 2003 but might be continued in the future. 2.4.3 USA The RTG would like to thank Alan C. Schulz from the NRL (the US...messages, threads, synchronisation, timer). • Language (C,C++, Java , ...) and programming model (OO, binary model-COM, CORBA, DCOM). At the higher

  1. Sea-Boson Analysis of the Infinite-U Hubbard Model

    OpenAIRE

    Setlur, Girish S.

    2004-01-01

    By expanding the projection operator in powers of the density fluctuations, we conjecture a hamiltonian purely quadratic in the sea-bosons that reproduces the right spin and charge velocities and exponent for the $ U = \\infty $ case in one dimension known from the work of Schulz. Then we argue that by simply promoting wavenumbers to wave vectors we are able to study the two dimensional case. We find that the quasiparticle residue takes a value $ Z_{F} = 0.79 $ close to half-filling where it i...

  2. Synthetic production of fuels by the Fischer Tropsch reaction using iron catalysts

    International Nuclear Information System (INIS)

    Rodriguez Cepeda, Rodrigo; Pacheco Ochoa, Luis

    2004-01-01

    A series of iron catalysts were prepared on three different types of supports: alumina and two activated carbons from eucalyptus woods and tagua seeds. Potassium was used as promoter and palladium was deposited by the excess wetness impregnation method. The catalysts were characterized by N 2 adsorption at 77 K, XRD and TPR analysis and evaluated as Fischer-Tropsch catalysts. The carbon supported catalysts favour the production of liquid hydrocarbons and decrease the aqueous phase. Those supported with alumina form gases and aqueous phase as the main products. The α p parameters of the Schulz-Flory distribution show hydrocarbons between gasoline and diesel

  3. A new genus and species of deep-sea glass sponge (Porifera, Hexactinellida, Aulocalycidae) from the Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Sautya, S.; Tabachnick, K.R.; Ingole, B.S.

    –XXVI. Schulze FE (1886) Über den Bau und das System der Hexactinelliden. Abhandlungen der Königlichen Akademie der Wissenschaften zu Berlin (Physikalisch-Mathematisch Classe) 1886: 1–97. Schmidt O (1880) Die Spongien des Meerbusen von Mexico (Und des... of Mexico, by the USCSS ‘Blake’. Gustav Fischer, Jena, 33–90, pls V-X. A new genus and species of deep-sea glass sponge... 21 Mehl D (1992) Die Entwicklung der Hexactinellida seit dem Mesozoikum. Paläobiologie, Phylogenie und Evolutionsökologie. Berliner...

  4. Highlights from the Biennial International Congress on Schizophrenia Research (ICOSR), April 21-25, 2013.

    Science.gov (United States)

    Curley, Allison A; Fisher, Helen L

    2013-01-01

    The 2013 International Congress on Schizophrenia Research, held in Orlando Grande Lakes, Florida, attracted over 1,000 attendees to the JW Marriott Hotel from 21-25 April 2013, not to mention the satellite meetings on cognition and the schizophrenia prodrome. With thanks to the Schizophrenia Research Forum (www.schizophreniaforum.org), a project of the Brain and Behavior Research Foundation, we bring you the following report on the Congress' sessions concerning DSM-5/ICD-11 and the psychosis continuum. We also want to thank Congress directors Carol Tamminga and Chuck Schulz, as well as meeting staff Dorothy Denton and Cristan Tamminga, for their gracious assistance.

  5. Contribution to Taxonomy and Distribution of the Genus Elaphropoda (Hymenoptera: Apidae: Apinae in Vietnam

    Directory of Open Access Journals (Sweden)

    Nguyen, Minh Phuong

    2016-04-01

    Full Text Available Taxonomic notes on the genus Elaphropoda Lieftinck, 1966 (Hymenoptera: Apidae from Vietnam are presented. Two species of the genus are reported: Elaphropoda percarinata (Cockerell, 1930 was first recorded from Vietnam based on specimens collected from Ha Tinh province in 1998, and is reconfirmed with a specimens collected from Bac Kan province in the Northeastern part of the country in this study, and Elaphropoda khasiana (Schulz, 1906 is recorded from Vietnam for the first time. Redescriptions of the male of E. percarinata and the female of E. khasiana are given with illustrations.

  6. Cloud and virtual data storage networking

    CERN Document Server

    Schulz, Greg

    2011-01-01

    The amount of data being generated, processed, and stored has reached unprecedented levels. Even during the recent economic crisis, there has been no slow down or information recession. Instead, the need to process, move, and store data has only increased. Consequently, IT organizations are looking to do more with what they have while supporting growth along with new services without compromising on cost and service delivery. Cloud and Virtual Data Storage Networking, by savvy IT industry veteran Greg Schulz, looks at converging IT resources and management technologies for facilitating efficie

  7. Viscometric studies of chitosan radiation degradation

    International Nuclear Information System (INIS)

    Rapado, M.; Ceausoglu, I.; Hunkeler, D.

    2001-01-01

    The paper presents the preliminary results, related to the viscometric studies on chitosan gamma radiation degradation. To follow the effects on the processes of chitosan transformations caused by irradiation in vacuum irradiated solutions changes of viscosity, and viscosity average molecular weight were measured The influence of absorbed dose on the chitosan molecular weight was studied using the Mark-Houwink-Sakurada equation. Various relationships for the for the determination of the intrinsic viscosity were made vias the Huggins, Kramer and Schulz- Blaschke models. The distinct decrease of intrinsic viscosity indicates that the main change scission was the dominating process

  8. Invasive alien trees and water resources in South Africa: case studies of the costs and benefits of management

    CSIR Research Space (South Africa)

    Le Maitre, David C

    2002-05-01

    Full Text Available -1127(01)00474-1 800 mm of rainfall annually, at altitudes below 2000 m, are covered by grasslands or shrublands, while similar areas in other parts of the world would support natural forests (Holdridge et al., 1971; Schulze and McGee, 1978). One of the main reasons...) 143?159 Phuthaditjhaba (Fig. 1). Large areas in this vicinity have been over-grazed and degraded because of the over-population of these fragile lands. The catchment is a key water supply area for the major industrial and urban areas of Greater...

  9. BAHASA ARAB BAKU DAN MODERN / AL-‘ARABIYAH AL-MU’ASHIRAH (Sebuah Alternatif

    Directory of Open Access Journals (Sweden)

    Raden Taufikurrahman

    2015-11-01

    Full Text Available Among as many as the problem of Arabic learning is availability of textbook to language learner itself. Not only that, more than that the textbook must answer the problem of language that is faced, and the material authenticity be the main review. The book “Bahasa Arab Baku dan Modern” by Prof. DR. Eckehard Schulz is one of Arabic textbook that is written by the author to answer the problem of language which is faced by Arabic learner that is related with four skills in language with short time, and with up dated topic and material

  10. Pseudoinverse preconditioners and iterative methods for large dense linear least-squares problems

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    Oskar Cahueñas

    2013-05-01

    Full Text Available We address the issue of approximating the pseudoinverse of the coefficient matrix for dynamically building preconditioning strategies for the numerical solution of large dense linear least-squares problems. The new preconditioning strategies are embedded into simple and well-known iterative schemes that avoid the use of the, usually ill-conditioned, normal equations. We analyze a scheme to approximate the pseudoinverse, based on Schulz iterative method, and also different iterative schemes, based on extensions of Richardson's method, and the conjugate gradient method, that are suitable for preconditioning strategies. We present preliminary numerical results to illustrate the advantages of the proposed schemes.

  11. Research in the Optical Sciences

    Science.gov (United States)

    1990-03-12

    Services Optics Program DTIC ELECTE .S FEB 2 419921 Robert R. Shannon, Director Optical Sciences Center University of Arizona Tucson, Arizona 85721...Kearney. A.R. Lampis. Z. Milanovic. D.W. Schulze, J.R. Roberts , J. Kerner. E.B. Saloman. and C.M. Falco. "Multilayer mirrors for 182 A." X-Ray/EUV...Boyd. M. 0. Raymer . P. Narum, and D. J. Harter. Phys. Rev. A 24. 411 (1981). 11. G. Khitrova. Ph.D. dissertation. New York University, 1986

  12. Helminth parasites of conventionally mantained laboratory mice

    Directory of Open Access Journals (Sweden)

    Roberto Magalhães Pinto

    1994-03-01

    Full Text Available The spectrum of intestinal parasites present in the SwissWebster, C57B1/6 and DBA/2 mice strains from different animal houses was identified and prevalences compared. Three parasites were observed during the course ofthis study, namely the cestode. Vampirolepis nana (Siebold, 1852 Spasskii, 1954(=Hymenolepis nana and the nematodes Aspiculuris tetraptera (Nitzsch, 1821 Schulz, 1924 and Syphacia obvelata (Rudolphi, 1802 Seurat, 1916. The scope of thisinvestigation has been widened to also include morphometric data on the parasites, to further simplify their identification, since the presence of helminths in laboratory animals is regarded as a restricting factor for the proper attainment of experimental protocols.

  13. The green and virtual data center

    CERN Document Server

    Schulz, Greg

    2009-01-01

    The Green and Virtual Data Center sets aside the political aspects of what is or is not considered green to instead focus on the opportunities for organizations that want to sustain environmentally-friendly economical growth. If you are willing to believe that IT infrastructure resources deployed in a highly virtualized manner can be combined with other technologies to achieve simplified and cost-effective delivery of services in a  green, profitable manner, this book is for you. Savvy industry veteran Greg Schulz provides real-world insight, addressing best practices, server, software, storag

  14. Comparison between human serum and Albuminar-20 (TM) supplement for in-vitro fertilization.

    Science.gov (United States)

    Staessen, C; Van den Abbeel, E; Carlé, M; Khan, I; Devroey, P; Van Steirteghem, A C

    1990-04-01

    Patient or fetal cord serum is commonly used as a protein supplement to culture media used in in-vitro fertilization (IVF). To eliminate the variability and possible hazards related to the use of human serum, a well-defined protein supplement, Albuminar-20 (Armour Pharmaceutical Cy) was evaluated as a substitute for serum. Prior to its application in the human, Earle's culture media supplemented with 0.5% (w/v) bovine serum albumin, 8% (v/v) decomplemented patient serum or 2.25% (v/v) Albuminar-20 were compared in a mouse bioassay. For the three different conditions, the percentages of blastocysts formed after 120 h in-vitro culture were respectively 91.2, 85.2 and 87.8% (NS). In the human IVF, a controlled comparison was performed from October to December 1988, between Earle's medium supplemented with patients' serum or Albuminar-20. When oocytes and spermatozoa were cultured in these two media, the fertilization rates were similar, 58.9% in human serum versus 59.4% in Albuminar-20. After further culture, the morphological quality of the cleaved embryos was better in the embryos cultured in Albuminar-20. The higher pregnancy rate in Albuminar-20 was correlated with the better morphological appearance of the embryos and their more advanced cleavage stage at the time of transfer. Therefore, Albuminar-20 can be considered as a suitable protein supplement in human IVF.

  15. Recusa Escolar: um Estudo de Caso em Ludoterapia Comportamental

    Directory of Open Access Journals (Sweden)

    Laura dos Santos Gomes Coelho

    Full Text Available Resumo Recusa Escolar é o termo que refere-se à dificuldade do estudante (criança ou adolescente em permanecer total ou parcialmente no ambiente escolar, gerando angústia e sofrimento. Ludoterapia comportamental foi utilizada no atendimento de Rita, uma menina (oito anos que recusava ir à escola. O atendimento consistiu em avaliação (entrevistas e observação e intervenções (alteração do padrão de brincar e orientações aos pais. Rita apresentou mudanças em termos de complexidade do lúdico e aceitação da escola. Teoria da motivação de Dember e Earl foi utilizada para explicar as escolhas lúdicas na direção hipotetizada; foi discutida a carência de detalhamento sobre a tomada de decisão em ludoterapia comportamental. É sugerido um modelo de tomada de decisão clínica que descreva como o psicólogo analisa as interações da criança com seu ambiente. Tal modelo de tomada de decisão deve ser capaz de incluir as características principais do conceito de lúdico presentes na teoria de Dember-Earl.

  16. Conference on offshore wind energy development in France and Germany - Legal framework, research results and perspectives

    International Nuclear Information System (INIS)

    Schulz, Joerg; Schlegelmilch, Kai; Schulze, Karsten; Abromeit, Carolin; Jensen, Lars Bie; Svendsen, Anne; Schwebel, Olivier; Huebner, Gundula; Heidmann, Roger; Piet, Olivier; Roudil, Jean-Philippe; Fuchs, Tina

    2010-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on offshore wind energy development in France and Germany. In the framework of this French-German exchange of experience, about 170 participants exchanged views on the actual policies, on the offshore potentialities of both countries and on the recent logistics, services, training and software innovations. This document brings together the available presentations (slides) made during this event: 1 - Opening talk by Joerg Schulz, Bremerhaven's Major; 2 - The Future of the Offshore Wind energy in Germany - Key elements of the German energy Concept (Kai Schlegelmilch); 3 - Offshore wind farms: A commercial perspective - Offshore projects profitability (Karsten Schulze); 4 - Offshore Wind Farms in the German EEZ - experiences with the German Approval Procedure: criteria for a successful approval procedure (Carolin Abromeit); 5 - Offshore Wind Parks and fishery in Denmark - Involvement and compensation of commercial fishery in Denmark (Lars Bie Jensen); 6 - Tourism, property value, residents interest and offshore parks - Usage conflicts or regional development? (Anne Svendsen); 7 - Logistics for offshore wind projects - classic ports usable? An overview (Roger Heidmann); 8 - Offshore wind energy and French harbours (Olivier Piet); 9 - French offshore wind power market and component suppliers (Jean-Philippe Roudil); 10 - Trident software - the Offshore Wind Manager. Review and Forecast after one year of construction (Tina Fuchs)

  17. Downward social comparison and subjective well-being in late life: the moderating role of perceived control.

    Science.gov (United States)

    Stewart, Tara L; Chipperfield, Judith G; Ruthig, Joelle C; Heckhausen, Jutta

    2013-01-01

    Drawing from Heckhausen and Schulz's Motivational Theory of Life-span Development, this study examined perceived control as a moderator of the protective relationship between downward social comparison and subjective well-being among older adults. Community-dwelling older adults (N = 97, 63% female, ages 79-97) were interviewed in their own homes at three time-points over a nine-year period. Interviews assessed older adults' perceived control over daily tasks, their use of downward social comparison in response to task restriction, and their subjective well-being. Regression analyses yielded a significant interaction between downward social comparison and perceived control for three subjective well-being outcomes: life satisfaction, perceived stress, and depressive symptoms. Follow-up analyses revealed that downward social comparison was associated with greater subjective well-being at low levels of perceived control; but was unrelated to subjective well-being at high levels of perceived control. These findings corroborate Heckhausen and Schulz's theorized goal-opportunity congruence premise and have implications for quality-of-life interventions to assist community-dwelling older adults.

  18. Pagan and bible beginning in the creative work of B.Shulz and F.Kafka

    Directory of Open Access Journals (Sweden)

    Ekaterina M. Reguretskaya

    2016-09-01

    Full Text Available Modern literature pays great attention to the study of biblical and pagan aspects of the classical works of the twentieth century. Franz Kafka and Bruno Schulz – two classics of modernity, residents of “Republic of dreams”, if to use a beautiful metaphor of Schultz, were from Jewish families lived in a multicultural and multilingual Austro-Hungarian Empire absorbed with best achievements of the Austrian culture. As noted by J. Updike: «Kafka and Schulz – two unremarkable man, born in the backyard of once powerful empire, took a bite at the same apple myth, but from different sides». Both were able to transform the insightful observation in prophecy, describing the dreams and nightmares as precisely as if they were facts of life, both shed light on human nature and witnessed history, complementing each other. I. Klekh rightly observes certain «commonness» of their creative method, stressing the importance for the two writers’ motif of transformation, transformation, mutual penetration of books and worlds. Shulz’s «fairy tale», his myth-making, guided by its own laws, “mythological” rules, which, unlike Kafka, is not «mythological» of closeness exclusively on internal self-perception.

  19. A strong shock tube problem calculated by different numerical schemes

    Science.gov (United States)

    Lee, Wen Ho; Clancy, Sean P.

    1996-05-01

    Calculated results are presented for the solution of a very strong shock tube problem on a coarse mesh using (1) MESA code, (2) UNICORN code, (3) Schulz hydro, and (4) modified TVD scheme. The first two codes are written in Eulerian coordinates, whereas methods (3) and (4) are in Lagrangian coordinates. MESA and UNICORN codes are both of second order and use different monotonic advection method to avoid the Gibbs phenomena. Code (3) uses typical artificial viscosity for inviscid flow, whereas code (4) uses a modified TVD scheme. The test problem is a strong shock tube problem with a pressure ratio of 109 and density ratio of 103 in an ideal gas. For no mass-matching case, Schulz hydro is better than TVD scheme. In the case of mass-matching, there is no difference between them. MESA and UNICORN results are nearly the same. However, the computed positions such as the contact discontinuity (i.e. the material interface) are not as accurate as the Lagrangian methods.

  20. A strong shock tube problem calculated by different numerical schemes

    International Nuclear Information System (INIS)

    Lee, W.H.; Clancy, S.P.

    1996-01-01

    Calculated results are presented for the solution of a very strong shock tube problem on a coarse mesh using (1) MESA code, (2) UNICORN code, (3) Schulz hydro, and (4) modified TVD scheme. The first two codes are written in Eulerian coordinates, whereas methods (3) and (4) are in Lagrangian coordinates. MESA and UNICORN codes are both of second order and use different monotonic advection method to avoid the Gibbs phenomena. Code (3) uses typical artificial viscosity for inviscid flow, whereas code (4) uses a modified TVD scheme. The test problem is a strong shock tube problem with a pressure ratio of 10 9 and density ratio of 10 3 in an ideal gas. For no mass-matching case, Schulz hydro is better than TVD scheme. In the case of mass-matching, there is no difference between them. MESA and UNICORN results are nearly the same. However, the computed positions such as the contact discontinuity (i.e. the material interface) are not as accurate as the Lagrangian methods. copyright 1996 American Institute of Physics

  1. ‘You think your writing belongs to you?’: Intertextuality in Contemporary Jewish Post-Holocaust Literature

    Directory of Open Access Journals (Sweden)

    Kirstin Gwyer

    2018-03-01

    Full Text Available This article examines a sub-category of recent Jewish post-Holocaust fiction that engages with the absent memory of the persecution its authors did not personally witness through the medium of intertextuality, but with intertextual recourse not to testimonial writing but to literature only unwittingly or retrospectively shadowed by the Holocaust. It will be proposed that this practice of intertextuality constitutes a response to the post-Holocaust Jewish author’s ‘anxiety of influence’ that, in the wake of the first generation’s experience of atrocity, their own life story and literature will always appear derivative. With reference to works by four such post-Holocaust authors, Jonathan Safran Foer’s Tree of Codes (2010, Maxim Biller’s Im Kopf von Bruno Schulz (2013, Helen Maryles Shankman’s In the Land of Armadillos (2016, and Nicole Krauss’s The History of Love (2005 and Forest Dark (2017, all of which engage intertextually with Franz Kafka and Bruno Schulz, it will be suggested that these authors are looking to return to a Kristevan practice of intertextuality after the predominantly citational recourse to antecedent material that has often characterized post-Holocaust literature. In the process, they also succeed in troubling recently popular conceptualizations of ‘postmemory’ literature as the ‘belated’ and ‘evacuated’ recipient of encrypted traumatic content inherited from the first generation that it must now seek either to preserve or to work through vicariously.

  2. New process controls in the co-fermentation of organic waste and municipal sewage sludge; Neue Verfahrensfuehrungen bei der Co-Vergaerung von Bioabfaellen und kommunalen Klaerschlaemmen

    Energy Technology Data Exchange (ETDEWEB)

    Schaepers, D.; Schierholt, M.; Buer, T.; Risse, H. [Technische Hochschule Aachen (DE). Inst. fuer Siedlungswasserwirtschaft (ISA)

    1999-07-01

    For the co-fermentation of organic waste and sewage sludge in digester towers at municipal sewage treatment plant, mainly single-stage processes have so far been studied or are in use in part. Within the framework of a project sponsored by the foundation Oswald-Schulze-Stiftung, the use of a two-stage mode of operation (thermophilic/mesophilic) for co-fermenting organic waste and sewage sludge was investigated. By adding organic waste to the digester content, biogas production per reactor volume was more than doubled in comparison with exclusive sewage sludge fermentation. Because of the thermophilic stage for the conditioning of organic waste, specific biogas yield for an organic load of 1.5 kg organic dry residue TR/m{sup 3*}d was slightly enhanced in comparison with single-stage co-fermentation. (orig.) [German] Zur Co-Vergaerung von Bioabfaellen und Klaerschlamm in Faultuermen kommunaler Klaeranlagen werden bislang hauptsaechlich einstufige Verfahren untersucht und teilweise eingesetzt. Im Rahmen eines von der Oswald-Schulze-Stiftung gefoerderten Projektes wurde der Einsatz einer 2-stufigen Betriebsweise (thermophil/mesophil) bei der Co-Vergaerung von Bioabfaellen und Klaerschlamm untersucht. Die Biogasproduktion pro Reaktorvolumen konnte durch die Zugabe von Bioabfall in die Faulbehaelter gegenueber der reinen Klaerschlammfaulung mehr als verdoppelt werden. Durch die thermophile Stufe zur Vorbehandlung der Bioabfaelle konnte die spezifische Biogasausbeute bei einer organischen Raumbelastung von 1,5 kg o TR/m{sup 3*}d gegenueber der 1-stufigen Co-Vergaerung leicht erhoeht werden. (orig.)

  3. They [do more than] Interrupt Us from Sadness: Exploring the impact of participatory music making on social determinants of health and wellbeing for refugees in Australia

    Directory of Open Access Journals (Sweden)

    N. Sunderland

    2015-07-01

    Full Text Available This paper reports on the outcomes of an exploratory narrative study on the impact of participatory music making on social determinants of health (SDOH and wellbeing for refugees in Brisbane, Australia. A key component of this exploratory research was to map health and wellbeing outcomes of music participation using an existing SDOH framework developed by researchers in the field of health promotion (Schulz & Northridge, 2004. This paper maps reported health and wellbeing outcomes for five refugee and asylum seeker members of a participatory Brisbane-based music initiative, the Scattered People, along an SDOH continuum ranging from individual level through to macro level fundamental determinants of health.While most themes emerging from this study corresponded to distinct categories in the Schulz and Northridge SDOH framework, three key aspects, which were critical to the achievement of wellbeing for participants, did not fit any of the pre-defined categories. These were: cultural expression, music making, and consolidation of personal and social identity. The importance of those themes to participants suggests that music and wellbeing studies involving culturally diverse groups and from a SDOH perspective may need to consider broader, more relevant concepts. The paper provides recommendations for future interdisciplinary research in this field. 

  4. Polibutadieno alto-cis: estudo viscosimétrico em tolueno e ciclo-hexano High-cis polybutadiene: viscometric study in toluene and cyclohexane

    Directory of Open Access Journals (Sweden)

    Ivana L. Mello

    2006-03-01

    Full Text Available Foram realizadas medidas viscosimétricas, em soluções de tolueno e ciclo-hexano, a 30°C, com polibutadieno alto-cis, sintetizado com catalisadores à base de neodímio. Foram empregadas diferentes equações para determinar os valores de viscosidade intrínseca: Huggins; Kraemer; Martin; e Schulz-Blaschke, por extrapolação gráfica; e Solomon-Ciuta; Deb-Chanterjee e; novamente, Schulz-Blaschke, por determinação por um único ponto. Os valores de viscosidade intrínseca obtidos pelos dois métodos (extrapolação gráfica e por um único ponto foram comparados a fim de se verificar a validade da determinação por um único ponto para os sistemas analisados, bem como determinar que equação fosse a mais adequada para esse tipo de cálculo. Foram calculadas as constantes viscosimétricas de Huggins, Kraemer e Schulz-Blaschke e foi feita uma análise da qualidade do solvente, levando-se em conta também os valores do parâmetro de solubilidade de Hildebrand dos solventes e do polímero. Foi determinada a distância média quadrática entre as extremidades das cadeias poliméricas por meio da equação de Flory, para tal foram utilizados os dados viscosimétricos obtidos, bem como os pesos moleculares determinados por viscosimetria e por cromatografia de exclusão por tamanho. Verificou-se que o método de determinação por um único ponto foi apropriado para o polibutadieno alto-cis, tanto para o cálculo de viscosidade intrínseca quanto de peso molecular. Em tolueno, a equação de Solomon-Ciuta foi a mais adequada, ao passo que a equação de Deb-Chanterjee foi mais apropriada para o polímero em ciclo-hexano. Verificou-se também que o tolueno foi o melhor solvente para o polibutadieno em função dos maiores valores de viscosidade intrínseca e de distância média quadrática entre os extremos da cadeia polimérica. Os valores obtidos para as constantes viscosimétricas confirmaram essa observação.Viscometric measurements, in

  5. Alarcón-Elbal, P.M. & Lucientes, J. 2012. Actualización del catálogo de Culicoides Latreille, 1809 (Diptera, Ceratopogonidae de España. Graellsia 68:353–362. doi:10.3989/graellsia.2012.v68.064. Bilk, S. Schulze, C. Fischer, M. Beer, M. Hlinak, A. & Hoffmann, B. 2012. Organ distribution of Schmallenberg virus RNA in malformed newborns. Vet. Microbiol. 159:236–238. doi:10.1016/j.vetmic.2012.03.035. De Blas, I., Ruiz-Zarzuela, I. & Vallejo, A. 2006. WinEpi: Working In Epidemiology. An Online Epidemiological Tool. Page in Proceedings of the 11th International Symposium on Veterinary Epidemiology and Economics, Cairns, Australia. Cameron, A.R. & Baldock, F.C. 1998. A new probability formula for surveys to substantiate freedom from disease.. Prev. Vet. Med. 34:1–17. Doceul, V., Lara, E., Sailleau, C., Belbis, G. Richardson, J., Bréard, E., Viarouge, C., Dominguez, M., Hendrikx, P., Calavas, D., Desprat, A., Languille, J., Comtet, L., Pourquier, P., Eléouët, J.-F., Delmas, B., Marianneau, P., Vitour, D. & Zientara, S. 2013. Epidemiology, molecular virology and diagnostics of Schmallenberg virus, an emerging orthobunyavirus in Europe.. Vet. Res. 44:1–13. doi:10.1186/1297-9716-44-31. Elbers, A.R.W., Meiswinkel, R., van Weezep, E., Sloet van Oldruitenborgh-Oosterbaan, M.M. & Engbert, A.K. 2013. Schmallenberg Virus in Culicoides spp. Biting Midges, the Netherlands, 2011. Emerg. Infect. Dis. 19:106–109. doi:10.3201/eid1901.121054. Gariglinany, M.-M., Hoffmann, B., Dive, M., Sartelet, A., Bayrou, C., Cassart, D., Beer, M. & Desmecht, D. 2012. Schmallenberg Virus in Calf Born at Term with Porencephaly, Belgium. Emerg. Infect. Dis. 18. doi:10.3201/eid1806.120104. Greiner, E.C., Mo, C.L., Homan, E.J., Gonzalez, J., Oviedo, M.T., Thompson, L.H. & Gibbs, E.P. 1993. Epidemiology of bluetongue in Central America and the Caribbean: initial entomological findings. Regional Bluetongue Team. Med Vet Entomol 7:309–315. doi:10.1111/j.1365-2915.1993.tb00697.x. Hern

    Directory of Open Access Journals (Sweden)

    Marlene Villegas-Salas

    2017-12-01

    Full Text Available Schmallenberg virus affects ruminants, which causes significant economic losses.  The virus is transmitted through vectors of the genus Culicoides; however, other studies do not rule out the possibility of sexual transmission due to its presence in semen. For this reason, the National Service of Animal Health of Costa Rica (SENASA imposed restrictions on the import of semen from animals from the European Union in 2013. Consequently, SENASA conducted a study to determine the presence or absence of antibodies against this virus in bovine, ovine and caprine samples. As a result, no antibodies against this virus were detected in the 748 samples tested. It was concluded that Schmallenberg virus was not circulating in Costa Rican ruminants during the tested period.

  6. Implementation of the European multicentre database of healthy controls for [{sup 123}I]FP-CIT SPECT increases diagnostic accuracy in patients with clinically uncertain parkinsonian syndromes

    Energy Technology Data Exchange (ETDEWEB)

    Albert, Nathalie L.; Unterrainer, Marcus; Xiong, Guoming; Bartenstein, Peter; Koch, Walter [University of Munich, Department of Nuclear Medicine, Munich (Germany); Diemling, Markus [Hermes Medical Solutions, Stockholm (Sweden); Varrone, Andrea [Karolinska University Hospital, Karolinska Institutet, Department of Clinical Neuroscience, Centre for Psychiatry Research, Stockholm (Sweden); Dickson, John C. [UCLH NHS Foundation Trust and University College, Institute of Nuclear Medicine, London (United Kingdom); Tossici-Bolt, Livia [University Hospitals Southampton NHS Trust, Department of Medical Physics, Southampton (United Kingdom); Sera, Terez [University of Szeged, Department of Nuclear Medicine and Euromedic Szeged, Szeged (Hungary); Asenbaum, Susanne [Medical University of Vienna, Department of Neurology, Vienna (Austria); Booij, Jan [University of Amsterdam, Department of Nuclear Medicine, Academic Medical Centre, Amsterdam (Netherlands); Kapucu, L. Oezlem A. [Gazi University, Department of Nuclear Medicine, Faculty of Medicine, Ankara (Turkey); Kluge, Andreas [ABX-CRO, Dresden (Germany); Ziebell, Morten [Rigshospitalet and University of Copenhagen, Neurobiology Research Unit, Copenhagen (Denmark); Darcourt, Jacques [University of Nice-Sophia Antipolis, Nuclear Medicine Department, Centre Antoine Lacassagne, Nice (France); Nobili, Flavio [University of Genoa, Clinical Neurology Unit, Department of Neuroscience (DINOGMI), Genoa (Italy); Pagani, Marco [Institute of Cognitive Sciences and Technologies, CNR, Rome (Italy); Karolinska Hospital, Department of Nuclear medicine, Stockholm (Sweden); Sabri, Osama [University of Leipzig, Department of Nuclear Medicine, Leipzig (Germany); Hesse, Swen [University of Leipzig, Department of Nuclear Medicine, Leipzig (Germany); Leipzig University Medical Centre, Molecular Neuroimaging IFB Adiposity Diseases, Leipzig (Germany); Borght, Thierry vander [Universite Catholique de Louvain, Nuclear Medicine Division, Mont-Godinne Medical Center, Yvoir (Belgium); Laere, Koen van [University Hospital and K.U. Leuven, Nuclear Medicine, Leuven (Belgium); Tatsch, Klaus [Staedtisches Klinikum Karlsruhe, Department of Nuclear Medicine, Karlsruhe (Germany); La Fougere, Christian [University of Tuebingen, Division of Nuclear Medicine, Department of Radiology, Tuebingen (Germany)

    2016-07-15

    Even though [{sup 123}I]FP-CIT SPECT provides high accuracy in detecting nigrostriatal cell loss in neurodegenerative parkinsonian syndromes (PS), some patients with an inconclusive diagnosis remain. We investigated whether the diagnostic accuracy in patients with clinically uncertain PS with previously inconclusive findings can be improved by the use of iterative reconstruction algorithms and an improved semiquantitative evaluation which additionally implemented a correction algorithm for patient age and gamma camera dependency (EARL-BRASS; Hermes Medical Solutions, Sweden). We identified 101 patients with inconclusive findings who underwent an [{sup 123}I]FP-CIT SPECT between 2003 and 2010 as part of the diagnostic process of suspected PS at the University of Munich, and re-evaluated these scans using iterative reconstruction algorithms and the new corrected EARL-BRASS. Clinical follow-up was obtained in 62 out of the 101 patients and constituted the gold standard for the re-evaluation to assess the possible improvement in diagnostic accuracy. Clinical follow-up confirmed the diagnosis of PS in 11 of the 62 patients. In patients in whom both visual and semiquantitative analysis showed concordant findings (48 patients), a high negative predictive value (93 %), positive predictive value (100 %) and accuracy (94 %) were found, and thus a correct diagnosis was obtained in 45 of the 48 patients. Among the 14 patients with discordant findings, the additional semiquantitative analysis correctly identified all five of nine patients patients without PS by nonpathological semiquantitative findings in visually pathological or inconclusive scans. In contrast, four of the remaining five patients with decreased semiquantitative values but visually normal scans did not show a PS during follow-up. The age-corrected and camera-corrected mode of evaluation using EARL-BRASS provided a notable improvement in the diagnostic accuracy of [{sup 123}I]FP-CIT SPECT in PS patients with

  7. Giacomo Castelvetro’s political translations: narrative strategies and literary style

    Directory of Open Access Journals (Sweden)

    Maria Luisa De Rinaldis

    2015-12-01

    Full Text Available Abstract - Translations of contemporary polemical and political tracts attributed to or associated with Giacomo Castelvetro (1546-1616 show a rejection of a servile adherence to the source text and the effort to produce an autonomous, readable text, one that in many cases is stylistically elevated and hence ‘literary’. Like most Renaissance translators, Castelvetro changes the form of expression of the texts and adopts narrative strategies in order to increase their communicative potential and reinforce the message they convey. An analysis of extracts from the translations of Discourse of the Maner of the Discovery of this late intended Treason (1605 and Elizabeth I’s proclamation By the Queen on the Seizure of the Earls of Essex, Rutland, Southampton (1600 will show how, through changes in emphasis and syntax, the translations give prominence to certain ‘characters’ in the narratives such as Guy Fawkes and the Earl of Essex. The stylistic elevation of the source text, moreover, shows how Castelvetro’s translations respond to a strong rhetorical tradition. Riassunto - Alcune traduzioni di testi contemporanei, di argomento politico e polemico, attribuite o associate a Giacomo Castelvetro (1546-1616 mostrano il rigetto di un’aderenza servile al testo d’origine e lo sforzo di produrre un testo autonomo, leggibile, che in molti casi è stilisticamente più elevato e quindi ‘letterario’. Come molti traduttori rinascimentali, Castelvetro cambia la forma espressiva dei testi e adotta strategie narrative per accrescere il potenziale comunicativo e rafforzare il messaggio. Un’analisi di estratti dalle traduzioni del Discourse of the Maner of the Discovery of this late intended Treason (1605 e del proclama di Elisabetta I  By the Queen on the Seizure of the Earls of Essex, Rutland, Southampton (1600 mostrerà come, attraverso cambiamenti di enfasi e di sintassi, le traduzioni diano risalto ad alcuni ‘personaggi’ della

  8. Implementation of the European multicentre database of healthy controls for [123I]FP-CIT SPECT increases diagnostic accuracy in patients with clinically uncertain parkinsonian syndromes

    International Nuclear Information System (INIS)

    Albert, Nathalie L.; Unterrainer, Marcus; Xiong, Guoming; Bartenstein, Peter; Koch, Walter; Diemling, Markus; Varrone, Andrea; Dickson, John C.; Tossici-Bolt, Livia; Sera, Terez; Asenbaum, Susanne; Booij, Jan; Kapucu, L. Oezlem A.; Kluge, Andreas; Ziebell, Morten; Darcourt, Jacques; Nobili, Flavio; Pagani, Marco; Sabri, Osama; Hesse, Swen; Borght, Thierry vander; Laere, Koen van; Tatsch, Klaus; La Fougere, Christian

    2016-01-01

    Even though [ 123 I]FP-CIT SPECT provides high accuracy in detecting nigrostriatal cell loss in neurodegenerative parkinsonian syndromes (PS), some patients with an inconclusive diagnosis remain. We investigated whether the diagnostic accuracy in patients with clinically uncertain PS with previously inconclusive findings can be improved by the use of iterative reconstruction algorithms and an improved semiquantitative evaluation which additionally implemented a correction algorithm for patient age and gamma camera dependency (EARL-BRASS; Hermes Medical Solutions, Sweden). We identified 101 patients with inconclusive findings who underwent an [ 123 I]FP-CIT SPECT between 2003 and 2010 as part of the diagnostic process of suspected PS at the University of Munich, and re-evaluated these scans using iterative reconstruction algorithms and the new corrected EARL-BRASS. Clinical follow-up was obtained in 62 out of the 101 patients and constituted the gold standard for the re-evaluation to assess the possible improvement in diagnostic accuracy. Clinical follow-up confirmed the diagnosis of PS in 11 of the 62 patients. In patients in whom both visual and semiquantitative analysis showed concordant findings (48 patients), a high negative predictive value (93 %), positive predictive value (100 %) and accuracy (94 %) were found, and thus a correct diagnosis was obtained in 45 of the 48 patients. Among the 14 patients with discordant findings, the additional semiquantitative analysis correctly identified all five of nine patients patients without PS by nonpathological semiquantitative findings in visually pathological or inconclusive scans. In contrast, four of the remaining five patients with decreased semiquantitative values but visually normal scans did not show a PS during follow-up. The age-corrected and camera-corrected mode of evaluation using EARL-BRASS provided a notable improvement in the diagnostic accuracy of [ 123 I]FP-CIT SPECT in PS patients with previously

  9. A critical review on the scaling theory of dispersion

    Science.gov (United States)

    Zech, Alraune; Mai, Juliane; Attinger, Sabine; Dietrich, Peter; Teutsch, Georg; Fiori, Aldo; Rubin, Yoram

    2014-05-01

    The phenomenon of dispersive mixing of solutes in aquifers is subject of research since decades. The characterization of dispersivity at a particular field site is a prerequisite to predict the movement and spreading of a contaminant plume. Experimental investigations have shown, that field-scale dispersivities vary over orders of magnitude, which apparently depends on the scale of measurement. Gelhar et al. [1992] and Schulze-Makuch [2005] have reviewed a large number of transport experiments reported in the literature. Based on that data Schulze-Makuch [2005] performed a trend analysis of longitudinal dispersivity, fostering the empirical relationship of a power law between dispersivities and the scale of measurement without an upper bound. The goal of our study is to critically revisit not only the data used for the trend analysis but the power-law scale dependence of longitudinal dispersivity (e.g. Neuman [1990], Xu and Eckstein [1995]). Our particular focus is on the reported dispersivities of large amount (larger than 100m) and large measurement scales (in the order of kilometers). We aim to evaluate current theories of transport against a critical "mass" of field experiments and to bracket the conditions of their applicability. We further aim to evaluate the adequacy of the field sampling techniques that were employed from the perspective of more than 30 years development in modeling and field characterization. Given the tremendous progress in field data acquisition techniques and new insights gained, it is reasonable to expect that interpretations of past experiments may be flawed due to the limitations or inadequacy of field sampling techniques. Gelhar, L.W., C. Welty, and K.R. Rehfeldt, 1992, A critical review of data on field-scale dispersion in aquifers, Water Resources Research 28, No. 7: 1955-1974. Schulze-Makuch, D., 2005, Longitudinal dispersivity data and implications for scaling behavior, Ground Water, Vol. 43, No. 3, 443-456. Neuman, S.P., 1990

  10. Effects of tectonics and large scale climatic changes on the evolutionary history of Hyalomma ticks.

    Science.gov (United States)

    Sands, Arthur F; Apanaskevich, Dmitry A; Matthee, Sonja; Horak, Ivan G; Harrison, Alan; Karim, Shahid; Mohammad, Mohammad K; Mumcuoglu, Kosta Y; Rajakaruna, Rupika S; Santos-Silva, Maria M; Matthee, Conrad A

    2017-09-01

    Hyalomma Koch, 1844 are ixodid ticks that infest mammals, birds and reptiles, to which 27 recognized species occur across the Afrotropical, Palearctic and Oriental regions. Despite their medical and veterinary importance, the evolutionary history of the group is enigmatic. To investigate various taxonomic hypotheses based on morphology, and also some of the mechanisms involved in the diversification of the genus, we sequenced and analysed data derived from two mtDNA fragments, three nuclear DNA genes and 47 morphological characters. Bayesian and Parsimony analyses based on the combined data (2242 characters for 84 taxa) provided maximum resolution and strongly supported the monophyly of Hyalomma and the subgenus Euhyalomma Filippova, 1984 (including H. punt Hoogstraal, Kaiser and Pedersen, 1969). A predicted close evolutionary association was found between morphologically similar H. dromedarii Koch, 1844, H. somalicum Tonelli Rondelli, 1935, H. impeltatum Schulze and Schlottke, 1929 and H. punt, and together they form a sister lineage to H. asiaticum Schulze and Schlottke, 1929, H. schulzei Olenev, 1931 and H. scupense Schulze, 1919. Congruent with morphological suggestions, H. anatolicum Koch, 1844, H. excavatum Koch, 1844 and H. lusitanicum Koch, 1844 form a clade and so also H. glabrum Delpy, 1949, H. marginatum Koch, 1844, H. turanicum Pomerantzev, 1946 and H. rufipes Koch, 1844. Wide scale continental sampling revealed cryptic divergences within African H. truncatum Koch, 1844 and H. rufipes and suggested that the taxonomy of these lineages is in need of a revision. The most basal lineages in Hyalomma represent taxa currently confined to Eurasia and molecular clock estimates suggest that members of the genus started to diverge approximately 36.25 million years ago (Mya). The early diversification event coincides well with the collision of the Indian and Eurasian Plates, an event that was also characterized by large scale faunal turnover in the region. Using S

  11. Platinum stable isotope analysis of geological standard reference materials by double-spike MC-ICPMS.

    Science.gov (United States)

    Creech, J B; Baker, J A; Handler, M R; Bizzarro, M

    2014-01-10

    We report a method for the chemical purification of Pt from geological materials by ion-exchange chromatography for subsequent Pt stable isotope analysis by multiple-collector inductively coupled plasma mass spectrometry (MC-ICPMS) using a 196 Pt- 198 Pt double-spike to correct for instrumental mass bias. Double-spiking of samples was carried out prior to digestion and chemical separation to correct for any mass-dependent fractionation that may occur due to incomplete recovery of Pt. Samples were digested using a NiS fire assay method, which pre-concentrates Pt into a metallic bead that is readily dissolved in acid in preparation for anion-exchange chemistry. Pt was recovered from anion-exchange resin in concentrated HNO 3 acid after elution of matrix elements, including the other platinum group elements (PGE), in dilute HCl and HNO 3 acids. The separation method has been calibrated using a precious metal standard solution doped with a range of synthetic matrices and results in Pt yields of ≥90% with purity of ≥95%. Using this chemical separation technique, we have separated Pt from 11 international geological standard reference materials comprising of PGE ores, mantle rocks, igneous rocks and one sample from the Cretaceous-Paleogene boundary layer. Pt concentrations in these samples range from ca. 5 ng g -1 to 4 μg g -1 . This analytical method has been shown to have an external reproducibility on δ 198 Pt (permil difference in the 198 Pt/ 194 Pt ratio from the IRMM-010 standard) of ±0.040 (2 sd) on Pt solution standards (Creech et al., 2013, J. Anal. At. Spectrom. 28, 853-865). The reproducibility in natural samples is evaluated by processing multiple replicates of four standard reference materials, and is conservatively taken to be ca. ±0.088 (2 sd). Pt stable isotope data for the full set of reference materials have a range of δ 198 Pt values with offsets of up to 0.4‰ from the IRMM-010 standard, which are readily resolved with this technique. These

  12. The discursive construction of risk and trust in patient information leaflets

    DEFF Research Database (Denmark)

    Fage-Butler, Antoinette Mary

    2011-01-01

    . This paper aims to analyse how risk is discursively constructed in PILs, and to identify and analyse discourses that are associated with trust-generation. The corpus (nine PILs chosen from the British online PIL bank, www.medicines.org.uk) is analysed using Foucauldian (1972) discourse analysis: specifically......, this involves identifying the functions of the statements of the potential harm that may be caused by taking the medication, whilst trust is constructed through three discourses: the discourses that relate to competence and care, in accordance with the trust theories of Poortinga/Pidgeon (2003) and Earle (2010......), and a third discourse, corporate accountability, which functions to construct an ethical (trustworthy) identity for the company. The paper contributes to PIL literature in the following ways: it introduces a methodology that has not been used before in relation to these texts, namely, Foucauldian discourse...

  13. Social-Economic Foundation for Smooth Changes in Korea

    Institute of Scientific and Technical Information of China (English)

    Wang Zaibang

    2012-01-01

    Chairman Kim Jong-il's death has sparked worldwide interest in the 'future direction of the D.P.R.K. political, economic, social and diplomatic policies. After all, as the youngest national leader in the world, Kim Jong-un has little experience, especially as he has been involved in national governance for such a very short time. Whether he earl unite all the high-level leaders of the ruling party, government and military and achieve a smooth transition in national political, economic and social life will affect the well-being of all Korean people, and the security and stability in the whole of Northeast Asia. However, a dispassionate analysis of North Korea's recent economic and social development may show that North Korea's future prospects may not be as gloomy as some people predict.

  14. Ho hum, another work of the devil. Buggery and sodomy in early Stuart England.

    Science.gov (United States)

    Burg, B R

    A study of contemporary handbooks for justices of the peace, sworn depositions, and other judicial records shows that in early Stuart England people were relatively tolerant of homosexuality. Sodomy was a minor felony, but more than homosexual activity was required to prosecute an offender. Persons accused of religious heresy, political offenses, or violating social-class distinctions also might be charged with sodomy, as illustrated by the cases of Lord Audley, Earl of Castlehaven and John Atherton, Bishop of Waterford and Lismore. Although the Puritans expanded the list of sexual acts proscribed as vices, even they did not react to it with the extreme horror characteristic of the Victorian era and the present day.

  15. A Digital Tool Supporting Goal-Oriented Teaching in Classrooms

    DEFF Research Database (Denmark)

    Misfeldt, Morten; Bundsgaard, Jeppe; Slot, Marie Falkesgaard

    2015-01-01

    and objectives for their teaching; these form a challenge and a basis for developing a digital tool for mediating between curriculum and pedagogical practice. The motivation for revising the national curriculum and developing digital tools that support teaching is partly based on evidence that the previous...... national curriculum was not used to any particular extent by teachers (Danish Evaluation Institute 2012). Hence, the curriculum has been rebuilt based on recent trends in school development and curriculum research suggesting the importance of a competence framework, learning goals, and the aggregation...... of classroom data for efficient teaching (Earl and Fullan 2003). Learning goals are supposed to support the students’ pace and sense of progression, inform classroom decisions, structure teachers’ planning, and support the dialogue between teachers, students, and parents (Hattie 2009). Based on these concerns...

  16. Evaluation of Life History Diversity, Habitat Connectivity, and Survival Benefits Associated with Habitat Restoration Actions in the Lower Columbia River and Estuary, Annual Report 2009

    Energy Technology Data Exchange (ETDEWEB)

    Diefenderfer, Heida L.; Johnson, Gary E.; Sather, Nichole K.; Skalski, John R.; Dawley, Earl M.; Coleman, Andre M.

    2010-08-01

    This report describes the 2009 research conducted under the U.S. Army Corps of Engineers (USACE or Corps) project EST-09-P-01, titled “Evaluation of Life History Diversity, Habitat Connectivity, and Survival Benefits Associated with Habitat Restoration Actions in the Lower Columbia River and Estuary.” The research was conducted by the Pacific Northwest National Laboratory, Marine Science Laboratory and Hydrology Group, in partnership with the University of Washington, School of Aquatic and Fishery Sciences, Columbia Basin Research, and Earl Dawley (NOAA Fisheries, retired). This Columbia River Fish Mitigation Program project, referred to as “Salmonid Benefits,” was started in FY 2009 to evaluate the state-of-the science regarding the ability to quantify the benefits to listed salmonids1 of habitat restoration actions in the lower Columbia River and estuary.

  17. Fifty years of pacemaker advancements.

    Science.gov (United States)

    Steinhaus, David

    2008-12-01

    A 1957 power blackout in Minnesota prompted C. Walton Lillehei, MD, a pioneer in open heart surgery, to ask Earl Bakken, the co-founder of Medtronic, Inc., to create a battery-operated pacemaker for pediatric patients. That conversation led to the development of the first external battery-operated pacemaker. That first bulky device is far removed from the tiny implantable computers available to heart patients today. Now, the size of two silver dollars stacked on top of one another, a pacemaker is prescribed for a person whose heart beats too slowly or pauses irregularly. Slightly larger devices have more recently evolved from pacing and regulating the heartbeat to being able to provide therapeutic high voltage shocks when needed to stop runaway fast heart rates, recording heart activity, and other physiologic functions, even resynchronizing the heart's chambers-all while providing information on the patient's condition and device performance to the doctor remotely or in the office.

  18. A Curriculum and Software Design Scaffolding Goal Directed Teaching in Classrooms

    DEFF Research Database (Denmark)

    Misfeldt, Morten; Bundsgaard, Jeppe; Slot, Marie Falkesgaard

    , the tool itself, and selected findings from qualitative and quantitative studies in the project. 2. International trends in goal oriented and data driven teaching The Danish curriculum reform builds on recent trends in school development and curriculum research suggesting the importance of a competence...... development and curriculum research suggesting the importance of a competence framework, learning goals and aggregation of classroom data to efficient teaching (Earl & Fullan 2003). Learning goals are supposed to support the student’s pace and sense of progression, inform classroom decisions, structure...... student has knowledge of text structure”). The curriculum can be presented in a number of graphical modes, e.g. in a matrix or in a hypertext structure. The curriculum reform was implemented in order to promote a goal oriented teaching and learning practice based heavily on research around data driven...

  19. Amino acid residues involved in ligand preference of the Snf3 transporter-like sensor in Saccharomyces cerevisiae

    DEFF Research Database (Denmark)

    Dietvorst, J.; Karhumaa, Kaisa; Kielland-Brandt, Morten

    2010-01-01

    /preferences of Snf3. The ability of cells to sense sugars in vivo was monitored by following the degradation of the Mth1 protein, :ill earl., event ill the signal pathway. Our study reveals that Snf3. ill addition to glucose. also senses fructose and mannose, as well as the glucose analogues 2-deoxyglucose, 3-O......-methylglucoside and 6-deoxyglucose. The signalling proficiency of a non-phosphorylatable analogue strongly supports the notion that sensing through Snf3 does not require sugar phosphorylation. Sequence comparisons of Snf3 to glucose transporters indicated amino acid residues possibly involved in sensing of sugars other...... than glucose. By site-specific mutagenesis of the structural gene, roles of specific residues in Snf3 could he established. Change of isoleucine-374 to valine ill transmembrane segment 7 of Snf3 partially abolished sensing of fructose mannose. while mutagenesis causing it change of phenylalanine-462 (4...

  20. John Locke and the case of Anthony Ashley Cooper.

    Science.gov (United States)

    Anstey, Peter R; Principe, Lawrence M

    2011-01-01

    In June 1668 Anthony Ashley Cooper, later to become the 1st Earl of Shaftesbury, underwent abdominal surgery to drain a large abscess above his liver. The case is extraordinary, not simply on account of the eminence of the patient and the danger of the procedure, but also because of the many celebrated figures involved. A trove of manuscripts relating to this famous operation survives amongst the Shaftesbury Papers in the National Archives at Kew. These include case notes in the hand of the philosopher John Locke and advice from leading physicians of the day including Francis Glisson, Sir George Ent and Thomas Sydenham. The majority of this material has never been published before. This article provides complete transcriptions and translations of all of these manuscripts, thus providing for the first time a comprehensive case history. It is prefaced with an extended introduction.

  1. Automated Metadata Formatting for Cornell’s Print-on-Demand Books

    Directory of Open Access Journals (Sweden)

    Dianne Dietrich

    2009-11-01

    Full Text Available Cornell University Library has made Print-On Demand (POD books available for many of its digitized out-of-copyright books. The printer must be supplied with metadata from the MARC bibliographic record in order to produce book covers. Although the names of authors are present in MARC records, they are given in an inverted order suitable for alphabetical filing rather than the natural order that is desirable for book covers. This article discusses a process for parsing and manipulating the MARC author strings to identify their various component parts and to create natural order strings. In particular, the article focuses on processing non-name information in author strings, such as titles that were commonly used in older works, e.g., baron or earl, and suffixes appended to names, e.g., "of Bolsena." Relevant patterns are identified and a Python script is used to manipulate the author name strings.

  2. Hotol and Saenger are good political trump cards

    Science.gov (United States)

    Ruppe, Harry O.

    Political and technological aspects of proposals for ESA reusable and/or SSTO launch vehicles (LVs) are examined in a critical review. The lack of reliable performance and cost estimates for such unconventional LV designs as Hotol, Saenger II, LART, ADV, and EARL is pointed out, and it is argued that progress toward the ESA goal of greater European space autonomy could be seriously endangered by abandoning or underfunding the current Ariane/Hermes LV program. The cost and reliability of expendable and reusable LV systems are discussed; two-stage and hybrid air-breathing engine concepts are compared; and the need for fundamental in-depth planning studies based on presently available technology or realistic projections is stressed. Long-term funding of such research at about 5 percent of present Ariane/Hermes levels is recommended.

  3. Thomas Birch's 'Weekly Letter' (1741-66): correspondence and history in the mid-eighteenth-century Royal Society.

    Science.gov (United States)

    Ellis, Markman

    2014-09-20

    Thomas Birch (1705-66), Secretary of the Royal Society from 1752 to 1765, and Philip Yorke, second Earl of Hardwicke (1720-90), wrote a 'Weekly Letter' from 1741 to 1766, an unpublished correspondence of 680 letters now housed in the British Library (Additional Mss 35396-400). The article examines the dimensions and purposes of this correspondence, an important conduit of information for the influential coterie of the 'Hardwicke circle' gathered around Yorke in the Royal Society. It explores the writers' self-conception of the correspondence, which was expressed in deliberately archaic categories of seventeenth-century news exchange, such as the newsletter, aviso and a-la-main. It shows how the letter writers negotiated their difference in status through the discourse of friendship, and concludes that the 'Weekly Letter' constituted for the correspondents a form of private knowledge, restricted in circulation to their discrete group, and as such unlike the open and networked model of Enlightenment science.

  4. Theology and bioethics: a marriage not made in heaven.

    Science.gov (United States)

    Boone, C Keith

    1986-10-01

    Boone reviews the 20th volume in the Philosophy and medicine series, Theology and Bioethics: Exploring the Foundations and Frontiers, edited by Earl E. Shelp (D. Reidel; 1985). The volume's theme, if and how "theology can make a unique contribution to bioethics in our time," is addressed by L. Walters, B. Mitchell, R. McCormick, M. Farley, P. Lehmann, C. Hartshorne, H.T. Engelhardt, S. Hauerwas, J. Childress, and W. Frankena, with a prologue by J. Nelson and an epilogue by J. Cobb. Boone briefly summarizes and critiques each essay. While he responds favorably to the volume, he also believes the work would have been stronger if more attention had been focused directly on the metaethical issues arising from the "gap between theological belief and moral action."

  5. Sound & The Society

    DEFF Research Database (Denmark)

    Schulze, Holger

    2014-01-01

    How are those sounds you hear right now socially constructed and evaluated, how are they architecturally conceptualized and how dependant on urban planning, industrial developments and political decisions are they really? How is your ability to hear intertwined with social interactions and their ...... and their professional design? And how is listening and sounding a deeply social activity – constructing our way of living together in cities as well as in apartment houses? A radio feature with Nina Backmann, Jochen Bonz, Stefan Krebs, Esther Schelander & Holger Schulze......How are those sounds you hear right now socially constructed and evaluated, how are they architecturally conceptualized and how dependant on urban planning, industrial developments and political decisions are they really? How is your ability to hear intertwined with social interactions...

  6. Intermediate steps towards the 2000-Watt society in Switzerland: an energy-economic scenario analysis

    International Nuclear Information System (INIS)

    Schulz, T. F.

    2007-01-01

    In this dissertation by Thorsten Frank Schulz the intermediate steps necessary to realise the 2000-Watt Society in Switzerland are examined. An analysis of an energy-economic scenario shows that the 2000-Watt Society should be seen as a long-term goal. According to the author, the major changes required to allow the implementation of this project concern energy-transformation and energy-demand technologies. Electricity will, according to the author, play an important role in a service-oriented society in the future. In such a transformation even intermediate steps are associated with considerable expense. The aims of the 2000-Watt Society project are listed. Energy and CO 2 balances for the domestic and transport sectors are presented and discussed. Complementary analyses are presented concerning fuel cells and wood-based fuel technologies. Finally, the implications of the 2000-Watt society and the effects of technological change are summarised and an outlook is presented

  7. Topological quantization of ensemble averages

    International Nuclear Information System (INIS)

    Prodan, Emil

    2009-01-01

    We define the current of a quantum observable and, under well-defined conditions, we connect its ensemble average to the index of a Fredholm operator. The present work builds on a formalism developed by Kellendonk and Schulz-Baldes (2004 J. Funct. Anal. 209 388) to study the quantization of edge currents for continuous magnetic Schroedinger operators. The generalization given here may be a useful tool to scientists looking for novel manifestations of the topological quantization. As a new application, we show that the differential conductance of atomic wires is given by the index of a certain operator. We also comment on how the formalism can be used to probe the existence of edge states

  8. NASA Green Flight Challenge: Conceptual Design Approaches and Technologies to Enable 200 Passenger Miles per Gallon

    Science.gov (United States)

    Wells, Douglas P.

    2011-01-01

    The Green Flight Challenge is one of the National Aeronautics and Space Administration s Centennial Challenges designed to push technology and make passenger aircraft more efficient. Airliners currently average around 50 passenger-miles per gallon and this competition will push teams to greater than 200 passenger-miles per gallon. The aircraft must also fly at least 100 miles per hour for 200 miles. The total prize money for this competition is $1.65 Million. The Green Flight Challenge will be run by the Comparative Aircraft Flight Efficiency (CAFE) Foundation September 25 October 1, 2011 at Charles M. Schulz Sonoma County Airport in California. Thirteen custom aircraft were developed with electric, bio-diesel, and other bio-fuel engines. The aircraft are using various technologies to improve aerodynamic, propulsion, and structural efficiency. This paper will explore the feasibility of the rule set, competitor vehicles, design approaches, and technologies used.

  9. Fluctuations of Wigner-type random matrices associated with symmetric spaces of class DIII and CI

    Science.gov (United States)

    Stolz, Michael

    2018-02-01

    Wigner-type randomizations of the tangent spaces of classical symmetric spaces can be thought of as ordinary Wigner matrices on which additional symmetries have been imposed. In particular, they fall within the scope of a framework, due to Schenker and Schulz-Baldes, for the study of fluctuations of Wigner matrices with additional dependencies among their entries. In this contribution, we complement the results of these authors by explicit calculations of the asymptotic covariances for symmetry classes DIII and CI and thus obtain explicit CLTs for these classes. On the technical level, the present work is an exercise in controlling the cumulative effect of systematically occurring sign factors in an involved sum of products by setting up a suitable combinatorial model for the summands. This aspect may be of independent interest. Research supported by Deutsche Forschungsgemeinschaft (DFG) via SFB 878.

  10. Contributions to the defocusing effect on pole figure measurements by X-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Palacios G, J.; Salat F, R. S.; Jimenez J, A.; Kryshtab, T., E-mail: palacios@esfm.ipn.mx [Instituto Politecnico Nacional, Escuela Superior de Fisica y Matematicas, Av. IPN s/n, 07738 Mexico D. F. (Mexico)

    2015-07-01

    A simple method, considering a parallel beam approximation has been made to reproduce the main features of the defocusing effect, observed when pole figures are measured with the Schulz reflection technique using X-ray diffraction. A Lorentzian curve was used to approximate the primary beam profile. This method applied to low index reflections of copper and silver shows qualitatively and partially quantitatively, the extent the elongation of the ellipse resulting from the intersection of the beam with the tilted sample causes the defocusing effect. Differences observed experimentally are attributed mainly to the divergence of the beam, but also partially to the particular primary beam profile. Additionally, measurements with two different vertical heights of the receiving slit, i. e. the measured arch length of the Debye-Scherrer ring, indicate that this parameter plays no role in defocusing. (Author)

  11. Association of inclusion body myositis with T cell large granular lymphocytic leukaemia

    DEFF Research Database (Denmark)

    Greenberg, Steven A; Pinkus, Jack L; Amato, Anthony A

    2016-01-01

    SEE HOHLFELD AND SCHULZE-KOOPS DOI101093/BRAIN/AWW053 FOR A SCIENTIFIC COMMENTARY ON THIS ARTICLE: Inclusion body myositis and T cell large granular lymphocytic leukaemia are rare diseases involving pathogenic cytotoxic CD8+ T cells. After encountering four patients with both disorders, we...... prospectively screened 38 patients with inclusion body myositis for the presence of expanded large granular lymphocyte populations by standard clinical laboratory methods (flow cytometry, examination of blood smears, and T cell receptor gene rearrangements), and performed muscle immunohistochemistry for CD8, CD......57, and TIA1. Most (22/38; 58%) patients with inclusion body myositis had aberrant populations of large granular lymphocytes in their blood meeting standard diagnostic criteria for T cell large granular lymphocytic leukaemia. These T cell populations were clonal in 20/20 patients and stably present...

  12. Understanding retirement: the promise of life-span developmental frameworks.

    Science.gov (United States)

    Löckenhoff, Corinna E

    2012-09-01

    The impending retirement of large population cohorts creates a pressing need for practical interventions to optimize outcomes at the individual and societal level. This necessitates comprehensive theoretical models that acknowledge the multi-layered nature of the retirement process and shed light on the dynamic mechanisms that drive longitudinal patterns of adjustment. The present commentary highlights ways in which contemporary life-span developmental frameworks can inform retirement research, drawing on the specific examples of Bronfenbrenner's Ecological Model, Baltes and Baltes Selective Optimization with Compensation Framework, Schulz and Heckhausen's Motivational Theory of Life-Span Development, and Carstensen's Socioemotional Selectivity Theory. Ultimately, a life-span developmental perspective on retirement offers not only new interpretations of known phenomena but may also help to identify novel directions for future research as well as promising pathways for interventions.

  13. THE GENIUS LOCI AT THE GREAT TEMPLE OF ABU SIMBEL: HERMENEUTIC READING IN THE ARCHITECTURAL LANGUAGE OF ANCIENT EGYPTIAN TEMPLES OF RAMSES II IN NUBIA

    Directory of Open Access Journals (Sweden)

    Nelly Ramzy

    2015-06-01

    Full Text Available Archaeologists have long wondered about the Temple of Abu Simbel: its location within the Nubian territory far from major Egyptian cities, and its unique design. Utilizing the hermeneutic process of understanding the whole from the parts and then situating the whole within a bigger whole (context, this study is a trial to arrive at a better interpretation of this monument. Drawing on the characteristic analysis of the temple's Genius Loci as developed by Norberg-Schulz, as well as on Heidegger's anticipatory fore-structures, the study goes on to show that both of the location and the unique structure of the temple were the outcome of political and conceptual aspects of the period, more than being a religious tradition. Reaching this conclusion, another goal had been achieved, where the validity of hermeneutic analyses as a useful tool for discovering new dimensions about historical monuments and archaeological sites had been attested.

  14. Projection-operator calculations of the lowest e(-)-He resonance

    Science.gov (United States)

    Berk, A.; Bhatia, A. K.; Junker, B. R.; Temkin, A.

    1986-01-01

    The 1s (2s)2:2S Schulz resonance of He(-) is investigated theoretically, applying the full projection-operator formalism developed by Temkin and Bhatia (1985) in a Rayleigh-Ritz variational calculation. The technique is described in detail, and results for five different approximations of the He target state are presented in a table. Good convergence is obtained, but it is found that even the best calculated value of the resonance is about 130 meV higher than the experimentally measured value of 19.367 + or - 0.007 eV (Brunt et al., 1977), a discrepancy attributed to the contribution of the shift in the Feshbach formalism.

  15. Two-step processing of oil shale to linear hydrocarbons

    Energy Technology Data Exchange (ETDEWEB)

    Eliseev, O.L.; Ryzhov, A.N.; Latypova, D.Zh.; Lapidus, A.L. [Russian Academy of Sciences, Moscow (Russian Federation). N.D. Zelinsky Institute of Organic Chemistry; Avakyan, T.A. [Gubkin Russian State University of Oil and Gas, Moscow (Russian Federation)

    2013-11-01

    Thermal and catalytic steam reforming of oil shale mined from Leningrad and Kashpir deposits was studied. Experiments were performed in fixed bed reactor by varying temperature and steam flow rate. Data obtained were approximated by empirical formulas containing some parameters calculated by least-squares method. Thus predicting amount of hydrogen, carbon monoxide and methane in producer gas is possible for given particular kind of oil shale, temperature and steam flow rate. Adding Ni catalyst enriches hydrogen and depletes CO content in effluent gas at low gasification temperatures. Modeling gas simulating steam reforming gases (H{sub 2}, CO, CO{sub 2}, and N{sub 2} mixture) was tested in hydrocarbon synthesis over Co-containing supported catalyst. Selectivity of CO conversion into C{sub 5+} hydrocarbons reaches 84% while selectivity to methane is 7%. Molecular weight distribution of synthesized alkanes obeys Anderson-Schulz-Flory equation and chain growth probability 0.84. (orig.)

  16. Bond charge approximation for valence electron density in elemental semiconductors

    International Nuclear Information System (INIS)

    Bashenov, V.K.; Gorbachov, V.E.; Marvakov, D.I.

    1985-07-01

    The spatial valence electron distribution in silicon and diamond is calculated in adiabatic bond charge approximation at zero temperature when bond charges have the Gaussian shape and their tensor character is taken into account. An agreement between theory and experiment has been achieved. For this purpose Xia's ionic pseudopotentials and Schulze-Unger's dielectric function are used. By two additional parameters Asub(B) and Zsub(B)sup(') we describe the spatial extent of the bond charge and local-field corrections, respectively. The parameter Zsub(B)sup(') accounts for the ratio between the Coulomb and exchange correlation interactions of the valence electrons and its silicon and diamond values have different signs. (author)

  17. Setting the agenda of a counter-terrorism strategic policy model

    Directory of Open Access Journals (Sweden)

    Emilia Ferone

    2018-03-01

    Full Text Available The aim of this paper is to present a functional model to fight terrorism from macro perspective through a “Strategic Policy Model” (SPM. The focus on legal order within the practices of Sociology of Law and Criminology is pivotal in order to reframe terrorism within a viable SPM. In “The Counterterrorism Handbook”, written by Bolz, Dudonis, and Schulz (2005, terrorism, at its very basic level, is defined as “an action that the urban guerrilla must execute with the greatest cold bloodedness, calmness and decision”. They further go on to provide a more scholarly definition: “the calculated use of violence to attain goals which are political, religious or ideological in nature. Terrorism involves a criminal act that is often symbolic in nature and intended to influence an audience beyond the immediate victims”.

  18. An isomerization-induced cage-breaking process in a molecular glass former below Tg

    International Nuclear Information System (INIS)

    Teboul, V.; Saiddine, M.; Accary, J.-B.; Nunzi, J.-M.

    2011-01-01

    A recent experimental [P. Karageorgiev, D. Neher, B. Schulz, B. Stiller, U. Pietsch, M. Giersig, L. Brehmer, Nature Mater. 4, 699 (2005)] study has found liquidlike diffusion below the glass-transition temperature in azobenzene-containing materials under irradiation. This result suggests that the isomerization-induced massive mass transport that leads to surface relief gratings formation in these materials, is induced by this huge increase of the matrix diffusion coefficient around the probe. In order to investigate the microscopic origin of the increase of the diffusion, we use molecular dynamics simulations of the photoisomerization of probe dispersed red 1 molecules dispersed inside a glassy molecular matrix. Results show that the increased diffusion is due to an isomerization-induced cage-breaking process. A process that explains the induced cooperative motions recently observed in these photoactive materials.

  19. Intermediate steps towards the 2000-Watt society in Switzerland: an energy-economic scenario analysis[Dissertation 17314

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, T. F

    2007-07-01

    In this dissertation by Thorsten Frank Schulz the intermediate steps necessary to realise the 2000-Watt Society in Switzerland are examined. An analysis of an energy-economic scenario shows that the 2000-Watt Society should be seen as a long-term goal. According to the author, the major changes required to allow the implementation of this project concern energy-transformation and energy-demand technologies. Electricity will, according to the author, play an important role in a service-oriented society in the future. In such a transformation even intermediate steps are associated with considerable expense. The aims of the 2000-Watt Society project are listed. Energy and CO{sub 2} balances for the domestic and transport sectors are presented and discussed. Complementary analyses are presented concerning fuel cells and wood-based fuel technologies. Finally, the implications of the 2000-Watt society and the effects of technological change are summarised and an outlook is presented.

  20. FEBEX bentonite colloid stability in ground water

    Energy Technology Data Exchange (ETDEWEB)

    Seher, H.; Schaefer, T.; Geckeis, H. [Inst. fuer Nukleare Entsorgung (INE), Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany)]. e-mail: holger.seher@ine.fzk .de; Fanghaenel, T. [Ruprecht-Karls-Univ. Heidelberg, Physikalisch-Chemisches In st., D-69120 Heidelberg (Germany)

    2007-06-15

    Coagulation experiments are accomplished to identify the geochemical conditions for the stability of Febex bentonite colloids in granite ground water. The experiments are carried out by varying pH, ionic strength and type of electrolyte. The dynamic light scattering technique (photon correlation spectroscopy) is used to measure the size evolution of the colloids with time. Agglomeration rates are higher in MgCl{sub 2} and CaCl{sub 2} than in NaCl solution. Relative agglomeration rates follow approximately the Schulze-Hardy rule. Increasing agglomeration rates at pH>8 are observed in experiments with MgCl{sub 2} and CaCl{sub 2} which are, however, caused by coprecipitation phenomena. Bentonite colloid stability fields derived from the colloid agglomeration experiments predict low colloid stabilization in granite ground water taken from Aespoe, Sweden, and relatively high colloid stability in Grimsel ground water (Switzerland)

  1. The Arabidopsis P4-ATPase ALA3 requires a ß-subunit to function in phospholipid translocation and secretory vesicle formation

    DEFF Research Database (Denmark)

    Lopez Marques, Rosa Laura

    The Arabidopsis P4-ATPase ALA3 requires a ß-subunit to function in phospholipid translocation and secretory vesicle formation   Lisbeth R. Poulsen1, Rosa L. López-Marqués1, Stephen C. McDowell2, Juha Okkeri3, Dirk Licht3, Alexander Schulz1, Thomas Pomorski3,  Jeffrey F. Harper2, and Michael G....... Palmgren1 1Centre for Membrane Pumps in Cells and Disease - PUMPKIN, Danish National Research Foundation, Department of Plant Biology, University of Copenhagen, DK-1871 Frederiksberg C, Denmark 2Biochemistry Department MS200, University of Nevada Reno, NV 89557, USA 3Humboldt-University Berlin, Faculty...... and in inducing membrane curvature, which is a requirement for vesicle formation. We show that Aminophospholipid ATPase3 (ALA3), a member of the P4-ATPase subfamily in the plant Arabidopsis thaliana, localizes to the Golgi apparatus and that genetic lesions of ALA3 result in impaired growth of roots and shoots...

  2. Evaluation and Adaption of the Trier Inventory for Chronic Stress (TICS) for Assessment in Competitive Sports

    Science.gov (United States)

    Sallen, Jeffrey; Hirschmann, Florian; Herrmann, Christian

    2018-01-01

    The demands of a career in competitive sports can lead to chronic stress perception among athletes if there is a non-conformity of requirements and available coping resources. The Trier Inventory for Chronic Stress (TICS) (Schulz et al., 2004) is said to be thoroughly validated. Nevertheless, it has not yet been subjected to a confirmatory factor analysis. The present study aims (1) to evaluate the factorial validity of the TICS within the context of competitive sports and (2) to adapt a short version (TICS-36). The total sample consisted of 564 athletes (age in years: M = 19.1, SD = 3.70). The factor structure of the original TICS did not adequately fit the present data, whereas the short version presented a satisfactory fit. The results indicate that the TICS-36 is an economical instrument for gathering interpretable information about chronic stress. For assessment in competitive sports with TICS-36, we generated overall and gender-specific norm values. PMID:29593611

  3. Projection-operator calculations of the lowest e--He resonance

    International Nuclear Information System (INIS)

    Berk, A.; Bhatia, A.K.; Junker, B.R.; Temkin, A.

    1986-01-01

    Results for the lowest (Schulz) autodetaching state of He - [1s(2s) 2 ] are reported. The calculation utilizes the full projection-operator formalism as explicitly developed by Temkin and Bhatia [Phys. Rev. A 31, 1259 (1985)]. Eigenvalues, scrE = , are calculated using projection operators Q depending on increasingly elaborate target wave functions going up to a 10-term Hylleraas-form, and a configuration-interaction total wave function Phi of 40 configurations. Results are well converged, but our best value is --0.13 eV above the experimental position at 19.37 eV. We conclude that the shift (Δ) in the Feshbach formalism gives a large contribution (relative to the width) to the position E/sub r/ ( = scrE+Δ). An appendix is devoted to the evaluation of the most complicated type of three-center integral involved in the calculation

  4. Evaluation and Adaption of the Trier Inventory for Chronic Stress (TICS) for Assessment in Competitive Sports.

    Science.gov (United States)

    Sallen, Jeffrey; Hirschmann, Florian; Herrmann, Christian

    2018-01-01

    The demands of a career in competitive sports can lead to chronic stress perception among athletes if there is a non-conformity of requirements and available coping resources. The Trier Inventory for Chronic Stress (TICS) (Schulz et al., 2004) is said to be thoroughly validated. Nevertheless, it has not yet been subjected to a confirmatory factor analysis. The present study aims (1) to evaluate the factorial validity of the TICS within the context of competitive sports and (2) to adapt a short version (TICS-36). The total sample consisted of 564 athletes (age in years: M = 19.1, SD = 3.70). The factor structure of the original TICS did not adequately fit the present data, whereas the short version presented a satisfactory fit. The results indicate that the TICS-36 is an economical instrument for gathering interpretable information about chronic stress. For assessment in competitive sports with TICS-36, we generated overall and gender-specific norm values.

  5. "Todos son genios". La crítica a la estetización de la acción política en Carl Schmitt.

    Directory of Open Access Journals (Sweden)

    Carlos A. Ramírez.

    2009-12-01

    Full Text Available In Political Romanticism, a work from 1919, Carl Schmitt interprets German romanticism as a “metaphysic” in which aesthetic concepts become the guiding concepts of all human activity. On this basis, he analyses and criticizes the effects of the expansion of aesthetic concerns on political action. This essay reconstructs Schmitt’s argument as a conceptual-historical genealogy of a modern discursive formation from which, as a by-product, a form of subjectivity now present in advanced capitalist societies was constituted. By contrasting Schmitt’s concept of the political in Political Romanticism with various works of contemporary sociology (Boltanski, Lipovetsky, Schulze, the article concludes by pointing out the political phenomena that are linked to the diffusion of this type of subjectivity.

  6. Study of the ion density of a radio-frequency plasma using electrostatic probes and focussed microwave interferometers

    International Nuclear Information System (INIS)

    Nguyen Cao, L.; Gagne, R.R.J.

    1976-01-01

    In order to verify experimentally and compare recent ion theories for cylindrical electrostatic probes, the ion density in a radio-frequency plasma was evaluated from V-I curves by means of six different theories. At low pressures, the theories of Bernstein and Rabinowitz, of Lam and Laframboise, give values of density which differ respectively by 20, 25 and 30% compared with the values obtained using a 10GHz focussed microwave interferometer. At the continuum limit, The Schulz and Brown's, and Su and Kiel's theories give density values which disagree respectively by 55 and 20%, compared with the values obtained by microwaves. For pressures varying from 0.05 to 3mmHg, the decrease of ion current, as predicted theorically by Waymouth, was observed. The density perturbation near the probe was found to be a dominant factor affecting the precision of density measurements, for pressures up to 2mmHg at least for our experimental conditions [fr

  7. Plutonium roundtable discussion

    International Nuclear Information System (INIS)

    Penneman, R.A.

    1982-01-01

    The roundtable discussion began with remarks by the chairman who pointed out the complicated nature of plutonium chemistry. Judging from the papers presented at this symposium, he noticed a pattern which indicated to him the result of diminished funding for investigation of basic plutonium chemistry and funding focused on certain problem areas. Dr. G.L. silver pointed to plutonium chemists' erroneous use of a simplified summary equation involving the disproportionation of Pu(EV) and their each of appreciation of alpha coefficients. To his appreciation of alpha coefficients. To his charges, Dr. J.T. Bell spoke in defense of the chemists. This discussion was followed by W.W. Schulz's comments on the need for experimental work to determine solubility data for plutonium in its various oxidation states under geologic repository conditions. Discussion then turned to plutonium pyrachemical process with Dana C. Christensen as the main speaker. This paper presents edited versions of participants' written version

  8. Characteristics of sedimentary organic matter in coastal and depositional areas in the Baltic Sea

    Science.gov (United States)

    Winogradow, A.; Pempkowiak, J.

    2018-05-01

    As organic matter (OM) is readily mineralized to carbon dioxide (Smith and Hollibangh, 1993; Emerson and Hedges, 2002; Szymczycha et al., 2017) it has a direct link to the carbon dioxide abundance in seawater and an indirect influence on the carbon dioxide concentration in the atmosphere (Emerson and Hedges, 2002; Schulz and Zabel, 2006). OM is a quantitatively minor yet important component of seawater. OM in seawater can originate from internal sources (marine, or planktonic, or autochthonous OM) or external sources (terrestrial, or allochtonous OM) (Maksymowska et al., 2000; Emerson and Hedges, 2002; Turnewitsch et al., 2007; Arndt et al., 2013). It is commonly divided into two fractions: dissolved (DOM) and particulate (POM). Organic carbon (OC) is, most often, used as a measure of OM.

  9. La entrada de inversión directa exterior en el sector financiero y su efecto sobre la productividad de la economía mexicana

    Directory of Open Access Journals (Sweden)

    Fernando Úbeda Mellina

    2016-02-01

    Full Text Available Los servicios financieros constituyen bienes intermedios (inputs y finales para el conjunto de los sectores de una economía, lo que los dota de una dimensión transversal. Dado que el output generado por estos servicios transversales afecta a la totalidad de la economía, cabe esperar que las externalidades derivadas de la entrada de la inversión directa exterior (ide en el sector financiero sean mayores que las derivadas de la entrada de ide en el sector manufacturero. Sin embargo, hemos obtenido evidencia de que las externalidades negativas de la ide manufacturera son mayores que las derivadas de la ide financiera. Los factores institucionales como la alta aversión al riesgo de la banca y la falta de intensidad en el marco competitivo pueden considerarse factores explicativos del resultado obtenido (Haber y Musacchio, 2005; Schulz, 2006.

  10. Dimensionality of civic participation in a convergent media environment

    DEFF Research Database (Denmark)

    Ohme, Jakob; Albæk, Erik; de Vreese, Claes Holger

    of online and offline, active and passive as well as traditional and unconventional forms of participation. Subsequently, the influence of exposure to political information on social media on these different types of participation was tested. Considering a change in citizenship (Bennett, 2008), especially......With the digitalization of information, subsequently leading to a fragmentation of audiences (Benett & Iyengar, 2008) and a change in the prevailing media logic (Schulz, 2014), a convergent media environment has developed. Nowadays, social media offer a platform for converging streams...... of information, altering the media diet for a growing share of the population. In addition, social networks like Facebook or Twitter offer emerging ways of participation, mostly with less effort than traditional forms. Yet, the role social media play in the political media diet was not fully assed by prior...

  11. The Social Structure of Participants of the Battle of Blore Heath (September 23, 1459

    Directory of Open Access Journals (Sweden)

    Andrey G. Prazdnikov

    2017-03-01

    Full Text Available The battle of Blore Heath which took place on September 23, 1459, marked the new stage of the Wars of Roses, which led to the change of dynasties at the English throne in less than two years. As it was not the clash of the main forces of House of Lancaster and House of York, the sources contain poor information about the battle’s participants. However, the analysis different sources let identify the names of 22 participants. Prosopographic study of this group contributes to the study of social behavior models, the degree of influence of the Wars of Roses on English society, the activity of representatives of different social strata. The social structure of the group, most of which are the representatives of the English gentry, is the object of the article. There is information in the sources about the origin of the knights. The House of York under the command of Earl of Salisbury were mostly from Northern and North-Western counties (Yorkshire, Westmorland, whereas House of Lancaster formed their troops in Cheshire, Staffordshire and Lancashire. As a rule, officers in the army of the Earl of Salisbury, were in close personal or family ties with him. The study of further lives of the participants of the battle and biographies of their children showed that the adherence of the chosen dynasty was preserved by generations and change of the parties was rather a deviation from the norm. English nobility of the second half of the 15th century had a high opinion of the value of loyalty and honor.

  12. The Largest Bio-Silica Structure on Earth: The Giant Basal Spicule from the Deep-Sea Glass Sponge Monorhaphis chuni

    Directory of Open Access Journals (Sweden)

    Xiaohong Wang

    2011-01-01

    Full Text Available The depth of the ocean is plentifully populated with a highly diverse fauna and flora, from where the Challenger expedition (1873–1876 treasured up a rich collection of vitreous sponges [Hexactinellida]. They have been described by Schulze and represent the phylogenetically oldest class of siliceous sponges [phylum Porifera]; they are eye-catching because of their distinct body plan, which relies on a filigree skeleton. It is constructed by an array of morphologically determined elements, the spicules. Later, during the German Deep Sea Expedition “Valdivia” (1898-1899, Schulze could describe the largest siliceous hexactinellid sponge on Earth, the up to 3 m high Monorhaphis chuni, which develops the equally largest bio-silica structures, the giant basal spicules (3 m × 10 mm. With such spicules as a model, basic knowledge on the morphology, formation, and development of the skeletal elements could be elaborated. Spicules are formed by a proteinaceous scaffold which mediates the formation of siliceous lamellae in which the proteins are encased. Up to eight hundred 5 to 10 μm thick lamellae can be concentrically arranged around an axial canal. The silica matrix is composed of almost pure silicon and oxygen, providing it with unusual optophysical properties that are superior to those of man-made waveguides. Experiments indicated that the spicules function in vivo as a nonocular photoreception system. In addition, the spicules have exceptional mechanical properties, combining mechanical stability with strength and stiffness. Like demosponges the hexactinellids synthesize their silica enzymatically, via the enzyme silicatein. All these basic insights will surely contribute also to a further applied utilization and exploration of bio-silica in material/medical science.

  13. The largest Bio-Silica Structure on Earth: The Giant Basal Spicule from the Deep-Sea Glass Sponge Monorhaphis chuni.

    Science.gov (United States)

    Wang, Xiaohong; Gan, Lu; Jochum, Klaus P; Schröder, Heinz C; Müller, Werner E G

    2011-01-01

    The depth of the ocean is plentifully populated with a highly diverse fauna and flora, from where the Challenger expedition (1873-1876) treasured up a rich collection of vitreous sponges [Hexactinellida]. They have been described by Schulze and represent the phylogenetically oldest class of siliceous sponges [phylum Porifera]; they are eye-catching because of their distinct body plan, which relies on a filigree skeleton. It is constructed by an array of morphologically determined elements, the spicules. Later, during the German Deep Sea Expedition "Valdivia" (1898-1899), Schulze could describe the largest siliceous hexactinellid sponge on Earth, the up to 3 m high Monorhaphis chuni, which develops the equally largest bio-silica structures, the giant basal spicules (3 m × 10 mm). With such spicules as a model, basic knowledge on the morphology, formation, and development of the skeletal elements could be elaborated. Spicules are formed by a proteinaceous scaffold which mediates the formation of siliceous lamellae in which the proteins are encased. Up to eight hundred 5 to 10 μm thick lamellae can be concentrically arranged around an axial canal. The silica matrix is composed of almost pure silicon and oxygen, providing it with unusual optophysical properties that are superior to those of man-made waveguides. Experiments indicated that the spicules function in vivo as a nonocular photoreception system. In addition, the spicules have exceptional mechanical properties, combining mechanical stability with strength and stiffness. Like demosponges the hexactinellids synthesize their silica enzymatically, via the enzyme silicatein. All these basic insights will surely contribute also to a further applied utilization and exploration of bio-silica in material/medical science.

  14. Giant siliceous spicules from the deep-sea glass sponge Monorhaphis chuni.

    Science.gov (United States)

    Wang, Xiaohong; Schröder, Heinz C; Müller, Werner E G

    2009-01-01

    Only 13 years after realizing, during a repair of a telegraph cable pulled out from the deep sea, that the depth of the ocean is plentifully populated with a highly diverse fauna and flora, the Challenger expedition (1873-1876) treasured up a rich collection of vitreous sponges (Hexactinellida). They had been described by Schulze and represent the phylogenetically oldest class of siliceous sponges (phylum Porifera); they are eye-catching because of their distinct body plan, which relies on a filigree skeleton. It is constructed by an array of morphologically determined elements, the spicules. Soon after, during the German Deep Sea Expedition "Valdivia" (1898-1899), Schulze could describe the largest siliceous hexactinellid sponge on Earth, the up to 3-m high Monorhaphis chuni, which develops the equally largest bio-silica structure, the giant basal spicules (3 mx10 mm). Using these spicules as a model, basic knowledge on the morphology, formation, and development of the skeletal elements could be achieved. They are formed by a proteinaceous scaffold (composed of a 27-kDa protein), which mediates the formation of the siliceous lamellae, into which the proteins are encased. The high number of 800 of 5-10 microm thick lamellae is concentrically arranged around the axial canal. The silica matrix is composed of almost pure silicon oxide, providing it with unusually optophysical properties, which are superior to those of man-made waveguides. Experiments might suggest that the spicules function in vivo as a nonocular photoreception system. In addition, the spicules have exceptional mechanical properties, combining mechanical stability with strength and stiffness. Like demosponges, also the hexactinellids synthesize their silica enzymatically, via the enzyme silicatein (27-kDa protein). It is suggested that these basic insights will surely contribute to a further applied utilization and exploration of silica in bio-material/biomedical science.

  15. Sulphur bacteria mediated formation of Palaeoproterozoic phosphorites

    Science.gov (United States)

    Joosu, Lauri; Lepland, Aivo; Kirsimäe, Kalle

    2014-05-01

    . Moreover, P-rich intervals in the Zaonega Formation are found in organic-rich sediments exhibiting strongly negative δ13Corg values (-37 to -34 per mil) which is interpreted to reflect the methanotrophic biomass. We conclude that modern-style phosphogenesis, mediated by sulphide-oxidising bacteria living in consortium with methanotrophs, was established at least 2 Ga ago. [1] Schulz and Schulz (2005) Science 307, 416-418 [2] Lepland, Joosu, Kirsimäe, Prave, Romashkin, Črne, Martin, Fallick, Somelar, Üpraus, Mänd, Roberts, van Zuilen, Wirth, Schreiber (2014) Nature geoscience 7, 20-24 [3] Bailey, Joye, Kalanetra, Flood, and Corsetti (2007) Nature 445, 198-201 [4] Schulz, Brinkhoff, Ferdelman, Marine, Teske and Jorgensen (1999) Science 284, 493-495 [5] Knittel, Losekann, Boetius, Kort and Amann (2005) Applied and Environmental Microbiology 71, 467-479.

  16. WE-AB-204-05: Harmonizing PET/CT Quantification in Multicenter Studies: A Case Study

    International Nuclear Information System (INIS)

    Marques da Silva, A; Fischer, A

    2015-01-01

    Purpose: To present the implementation of a strategy to harmonize FDG PET/CT quantification (SUV), performed with different scanner models and manufacturers. Methods: The strategy was based on Boellaard (2011) and EARL FDG-PET/CT accreditation program, that propose quality control measurements for harmonizing scanner performance. A NEMA IEC Body phantom study was performed using four different devices: PHP-1 (Gemini TF Base, Philips); PHP-2 (Gemini GXL, Philips); GEH (Discovery 600, General Electric); SMS (Biograph Hi-Rez 16, Siemens). The SUV Recovery Coefficient (RC) was calculated using the clinical protocol and other clinically relevant reconstruction parameters. The most appropriate reconstruction parameters (MARP) for SUV harmonization, in each scanner, are those which achieve EARL harmonizing standards. They were identified using the lowest root mean square errors (RMSE). To evaluate the strategy’s effectiveness, the Maximum Differences (MD) between the clinical and MARP RC values were calculated. Results: The reconstructions parameters that obtained the lowest RMSE are: FBP 5mm (PHP-1); LOR-RAMLA 2i0.008l (PHP-2); VuePointHD 2i32s10mm (GEH); and FORE+OSEM 4i8s6mm (SMS). Thus, to ensure that quantitative PET image measurements are interchangeable between these sites, images must be reconstructed with the above-mentioned parameters. Although, a decoupling between the best image for PET/CT qualitative analysis and the best image for quantification studies was observed. The MD showed that the strategy was effective in reducing the variability of SUV quantification for small structures (<17mm). Conclusion: The harmonization strategy of the SUV quantification implemented with these devices was effective in reducing the variability of small structures quantification, minimizing the inter-scanner and inter-institution differences in quantification. However, it is essential that, in addition to the harmonization of quantification, the standardization of the

  17. {sup 18}F-FDG PET/CT heterogeneity quantification through textural features in the era of harmonisation programs: a focus on lung cancer

    Energy Technology Data Exchange (ETDEWEB)

    Lasnon, Charline [University Hospital, Nuclear Medicine Department, Caen (France); Biologie et Therapies Innovantes des Cancers Localement Agressifs, Universite de Caen Normandie, INSERM, Caen (France); Normandie University, Caen (France); Majdoub, Mohamed; Lavigne, Brice; Visvikis, Dimitris [LaTIM, INSERM UMR 1101, Brest (France); Do, Pascal [Thoracic Oncology, Francois Baclesse Cancer Centre, Caen (France); Madelaine, Jeannick [Caen University Hospital, Pulmonology Department, Caen (France); Hatt, Mathieu [LaTIM, INSERM UMR 1101, Brest (France); CHRU Morvan, INSERM UMR 1101, Laboratoire de Traitement de l' Information Medicale (LaTIM), Groupe ' Imagerie multi-modalite quantitative pour le diagnostic et la therapie' , Brest (France); Aide, Nicolas [University Hospital, Nuclear Medicine Department, Caen (France); Biologie et Therapies Innovantes des Cancers Localement Agressifs, Universite de Caen Normandie, INSERM, Caen (France); Normandie University, Caen (France); Caen University Hospital, Nuclear Medicine Department, Caen (France)

    2016-12-15

    Quantification of tumour heterogeneity in PET images has recently gained interest, but has been shown to be dependent on image reconstruction. This study aimed to evaluate the impact of the EANM/EARL accreditation program on selected {sup 18}F-FDG heterogeneity metrics. To carry out our study, we prospectively analysed 71 tumours in 60 biopsy-proven lung cancer patient acquisitions reconstructed with unfiltered point spread function (PSF) positron emission tomography (PET) images (optimised for diagnostic purposes), PSF-reconstructed images with a 7-mm Gaussian filter (PSF{sub 7}) chosen to meet European Association of Nuclear Medicine (EANM) 1.0 harmonising standards, and EANM Research Ltd. (EARL)-compliant ordered subset expectation maximisation (OSEM) images. Delineation was performed with fuzzy locally adaptive Bayesian (FLAB) algorithm on PSF images and reported on PSF{sub 7} and OSEM ones, and with a 50 % standardised uptake values (SUV){sub max} threshold (SUV{sub max50%}) applied independently to each image. Robust and repeatable heterogeneity metrics including 1st-order [area under the curve of the cumulative histogram (CH{sub AUC})], 2nd-order (entropy, correlation, and dissimilarity), and 3rd-order [high-intensity larger area emphasis (HILAE) and zone percentage (ZP)] textural features (TF) were statistically compared. Volumes obtained with SUV{sub max50%} were significantly smaller than FLAB-derived ones, and were significantly smaller in PSF images compared to OSEM and PSF{sub 7} images. PSF-reconstructed images showed significantly higher SUVmax and SUVmean values, as well as heterogeneity for CH{sub AUC}, dissimilarity, correlation, and HILAE, and a wider range of heterogeneity values than OSEM images for most of the metrics considered, especially when analysing larger tumours. Histological subtypes had no impact on TF distribution. No significant difference was observed between any of the considered metrics (SUV or heterogeneity features) that we

  18. 18F-FDG PET/CT heterogeneity quantification through textural features in the era of harmonisation programs: a focus on lung cancer.

    Science.gov (United States)

    Lasnon, Charline; Majdoub, Mohamed; Lavigne, Brice; Do, Pascal; Madelaine, Jeannick; Visvikis, Dimitris; Hatt, Mathieu; Aide, Nicolas

    2016-12-01

    Quantification of tumour heterogeneity in PET images has recently gained interest, but has been shown to be dependent on image reconstruction. This study aimed to evaluate the impact of the EANM/EARL accreditation program on selected 18 F-FDG heterogeneity metrics. To carry out our study, we prospectively analysed 71 tumours in 60 biopsy-proven lung cancer patient acquisitions reconstructed with unfiltered point spread function (PSF) positron emission tomography (PET) images (optimised for diagnostic purposes), PSF-reconstructed images with a 7-mm Gaussian filter (PSF 7 ) chosen to meet European Association of Nuclear Medicine (EANM) 1.0 harmonising standards, and EANM Research Ltd. (EARL)-compliant ordered subset expectation maximisation (OSEM) images. Delineation was performed with fuzzy locally adaptive Bayesian (FLAB) algorithm on PSF images and reported on PSF 7 and OSEM ones, and with a 50 % standardised uptake values (SUV) max threshold (SUV max50% ) applied independently to each image. Robust and repeatable heterogeneity metrics including 1st-order [area under the curve of the cumulative histogram (CH AUC )], 2nd-order (entropy, correlation, and dissimilarity), and 3rd-order [high-intensity larger area emphasis (HILAE) and zone percentage (ZP)] textural features (TF) were statistically compared. Volumes obtained with SUV max50% were significantly smaller than FLAB-derived ones, and were significantly smaller in PSF images compared to OSEM and PSF 7 images. PSF-reconstructed images showed significantly higher SUVmax and SUVmean values, as well as heterogeneity for CH AUC , dissimilarity, correlation, and HILAE, and a wider range of heterogeneity values than OSEM images for most of the metrics considered, especially when analysing larger tumours. Histological subtypes had no impact on TF distribution. No significant difference was observed between any of the considered metrics (SUV or heterogeneity features) that we extracted from OSEM and PSF 7

  19. "1"8F-FDG PET/CT heterogeneity quantification through textural features in the era of harmonisation programs: a focus on lung cancer

    International Nuclear Information System (INIS)

    Lasnon, Charline; Majdoub, Mohamed; Lavigne, Brice; Visvikis, Dimitris; Do, Pascal; Madelaine, Jeannick; Hatt, Mathieu; Aide, Nicolas

    2016-01-01

    Quantification of tumour heterogeneity in PET images has recently gained interest, but has been shown to be dependent on image reconstruction. This study aimed to evaluate the impact of the EANM/EARL accreditation program on selected "1"8F-FDG heterogeneity metrics. To carry out our study, we prospectively analysed 71 tumours in 60 biopsy-proven lung cancer patient acquisitions reconstructed with unfiltered point spread function (PSF) positron emission tomography (PET) images (optimised for diagnostic purposes), PSF-reconstructed images with a 7-mm Gaussian filter (PSF_7) chosen to meet European Association of Nuclear Medicine (EANM) 1.0 harmonising standards, and EANM Research Ltd. (EARL)-compliant ordered subset expectation maximisation (OSEM) images. Delineation was performed with fuzzy locally adaptive Bayesian (FLAB) algorithm on PSF images and reported on PSF_7 and OSEM ones, and with a 50 % standardised uptake values (SUV)_m_a_x threshold (SUV_m_a_x_5_0_%) applied independently to each image. Robust and repeatable heterogeneity metrics including 1st-order [area under the curve of the cumulative histogram (CH_A_U_C)], 2nd-order (entropy, correlation, and dissimilarity), and 3rd-order [high-intensity larger area emphasis (HILAE) and zone percentage (ZP)] textural features (TF) were statistically compared. Volumes obtained with SUV_m_a_x_5_0_% were significantly smaller than FLAB-derived ones, and were significantly smaller in PSF images compared to OSEM and PSF_7 images. PSF-reconstructed images showed significantly higher SUVmax and SUVmean values, as well as heterogeneity for CH_A_U_C, dissimilarity, correlation, and HILAE, and a wider range of heterogeneity values than OSEM images for most of the metrics considered, especially when analysing larger tumours. Histological subtypes had no impact on TF distribution. No significant difference was observed between any of the considered metrics (SUV or heterogeneity features) that we extracted from OSEM and PSF_7

  20. Holocene Millennial Time Scale Hydrological Changes In Central-east Africa

    Science.gov (United States)

    Jolly, D.; Bonnefille, R.; Beaufort, L.

    The Holocene hydrological changes of a tropical swamp is reconstructed using a high resolution pollen record (ca 50 yrs) from the Kuruyange valley (Burundi, Africa, 3°35'S, 29°41'E), at 2000 m elevation. The sequence was dated by 10 radiocarbon dates, allowing reconstruction between ca 12 500 and 1000 cal yr B.P. In the Kuruyange swamp, peat accumulated rapidly at a sedimentation rate varying from 0.73 (prior to 6200 cal yr B.P.) to 1.51 mm/yr (during the late Holocene). A pollen index of water table, based on a ratio of aquatic versus non-aquatic plants has been used in order to test the hypothesis of hydrological constraints on the swampy ecosystem. Eight arid phases are evidenced by the index minima at 12 200, 11 200, 9900, 8600, 6500, 5000, 3400, 1600 cal yr B.P. The good agreement existing between this index and independent data such as (i) low-resolution East-African lake level reconstruct ions (Gillespie et al., 1983) and (ii) ?18O analyses from Arabian Sea (Sirocko et al., 1993) suggests the water table level responds to the monsoon dynamic. The Index varies periodically with a combination of 1/1515, 1/880 and 1/431 years-1 frequencies, revealed by time series analyses (Blackman-Tukey and Maximum Entropy). The extrapolation of the composite curve based on these 3 periodicities show that two major climatic events defined in the high latitudes between 1000 and 660 cal yr B.P. (Medieval Warm Period) and between 500 and 100 cal yr B.P. (Little Ice Age) are recorded in our data and show respectively high and low stands of the water table. Our results support some previous pollen-derived climate estimates in Ethiopia done by Bonnefille and Umer (1994). Moreover, the "1500 year" cycle registered in our data from the tropics, already evidenced in higher latitudes (Wijmstra et al., 1984; Bondet al., 1997; Schulz et al., 1999; Bond et al., 2001) support the hypothesis of strong teleconnections between tropical/subtropical and polar climates during the deglaciation

  1. Platelet-rich-plasmapheresis for minimising peri-operative allogeneic blood transfusion.

    Science.gov (United States)

    Carless, Paul A; Rubens, Fraser D; Anthony, Danielle M; O'Connell, Dianne; Henry, David A

    2011-03-16

    Concerns regarding the safety of transfused blood have generated considerable enthusiasm for the use of technologies intended to reduce the use of allogeneic blood (blood from an unrelated donor). Platelet-rich plasmapheresis (PRP) offers an alternative approach to blood conservation. To examine the evidence for the efficacy of PRP in reducing peri-operative allogeneic red blood cell (RBC) transfusion, and the evidence for any effect on clinical outcomes such as mortality and re-operation rates. We identified studies by searching MEDLINE (1950 to 2009), EMBASE (1980 to 2009), The Cochrane Library (Issue 1, 2009), the Internet (to March 2009) and the reference lists of published articles, reports, and reviews. Controlled parallel group trials in which adult patients, scheduled for non-urgent surgery, were randomised to PRP, or to a control group which did not receive the intervention. Primary outcomes measured were: the number of patients exposed to allogeneic RBC transfusion, and the amount of RBC transfused. Other outcomes measured were: the number of patients exposed to allogeneic platelet transfusions, fresh frozen plasma, and cryoprecipitate, blood loss, re-operation for bleeding, post-operative complications (thrombosis), mortality, and length of hospital stay. Treatment effects were pooled using a random-effects model. Trial quality was assessed using criteria proposed by Schulz et al (Schulz 1995). Twenty-two trials of PRP were identified that reported data for the number of patients exposed to allogeneic RBC transfusion. These trials evaluated a total of 1589 patients. The relative risk (RR) of exposure to allogeneic blood transfusion in those patients randomised to PRP was 0.73 (95%CI 0.59 to 0.90), equating to a relative risk reduction (RRR) of 27% and a risk difference (RD) of 19% (95%CI 10% to 29%). However, significant heterogeneity of treatment effect was observed (p transfused (weighted mean difference [WMD] -0.69, 95%CI -1.93 to 0.56 units). Trials

  2. Preliminary survey for entomopathogenic fungi associated with Ixodes scapularis>/i> (Acari: Ixodidae) in southern New York and New England, USA

    Science.gov (United States)

    Zhioua, Elyes; Ginsberg, Howard S.; Humber, Richard A.; LeBrun, Roger A.

    1999-01-01

    Free-living larval, nymphal, and adult Ixodes scapularis Say were collected from scattered locales in southern New England and New York to determine infection rates with entomopathogenic fungi. Infection rates of larvae, nymphs, males, and females were 0% (571), 0% (272), 0% (57), and 4.3% (47), respectively. Two entomopathogenic fungi were isolated from field-collected I. scapularis females from Fire Island, NY. Isolates were identified as Verticillium lecanii (Zimmermann) Viegas and Verticillium sp. (a member of the Verticillium lecanii species complex).Ixodes scapularis Say is the principal vector of Borrelia burgdorferi Johnson, Schmid, Hyde, Steigerwalt & Brenner (Burgdorfer et al. 1982, Johnson et al. 1984), the etiologic agent of Lyme disease in the northeastern and upper-midwestern United States. Control of I. scapularis is based on chemical treatment (Mather et al. 1987b; Schulze et al. 1987, 1991), environmental management (Wilson et al. 1988, Schulze et al. 1995), and habitat modification (Wilson 1986). These methods have shown variable success, and some potentially have negative environmental effects (Wilson and Deblinger 1993, Ginsberg 1994).Studies concerning natural predators, parasitoids, and pathogens of I. scapularis are rare. The use of ground-dwelling birds as tick predators has had only limited success (Duffy et al. 1992). Nymphal I. scapularis are often infected with the parasitic wasp Ixodiphagus hookeri (Howard) (Mather et al. 1987a, Hu et al. 1993, Stafford et al. 1996, Hu and Hyland 1997), but this wasp does not effectively control I. scapularis populations (Stafford et al. 1996). The entomopathogenic nematodes Steinernema carpocapsae (Weiser) and S. glaseri (Steiner) are pathogenic only to engorged female I. scapularis, and thus have limited applicability (Zhioua et al. 1995). In contrast, the entomogenous fungus Metarhizium anisopliae (Metschnikoff) Sorokin is highly pathogenic to all stages of I. scapularis, unfed as well as engorged

  3. Die ontwikkeling van die menslike bewussyn: Ken Wilber se AQAL-teorie

    Directory of Open Access Journals (Sweden)

    Ignatius (Naas W. Ferreira

    2010-02-01

    Kenneth Earl Wilber III, an integral philosopher, psychologist and mystic with an intelligence quotient of 160, was born on 31 January 1949 in Oklahoma City, Oklahoma, in the United States of America, and is considered by some as one of the most important philosophers of the 21st century. He developed his integral philosophy over 30 years, which can be divided into five phases. The most important aspects of his philosophy for the purposes of this article are the AQAL integral map of reality, and the evolution of consciousness. AQAL stands for ‘all quadrants, all levels, lines and stages’. Wilber divides reality into singular and plural interiors and exteriors; or art, morals and science. Also deriving ideas from Developmental Psychology, he sees the evolution of consciousness unfolding in seven stages: archaic, magic, mythic, rational, pluralistic, holistic and transpersonal. This theory could add value to pastoral care by enabling pastors to support believers’ own spiritual growth in pursuit of the kingdom of heaven.

  4. Exploring cell apoptosis and senescence to understand and treat cancer: an interview with Scott Lowe

    Directory of Open Access Journals (Sweden)

    2015-11-01

    Full Text Available Scott W. Lowe is currently principal investigator at the Memorial Sloan-Kettering Cancer Center. After beginning his studies in chemical engineering, he decided to take another path and became fascinated by biochemistry, genetics and molecular biology, which ultimately led to an interest in human disease, particularly cancer. During his PhD at the Massachusetts Institute of Technology (MIT, Scott had the opportunity to benefit from the exceptional mentorship of Earl Ruley, David Housman and Tyler Jacks, and contributed to elucidating how the p53 (TP53 tumor suppressor gene limits oncogenic transformation and modulates the cytotoxic response to conventional chemotherapy. This important work earned him a fellowship from the Cold Spring Harbor Laboratory, which helped to launch his independent career. Scott is now a leading scientist in the cancer field and his work has helped to shed light on mechanisms of cell apoptosis and senescence to better understand and treat cancer. In this interview, he talks about this incredible scientific journey.

  5. Orrery a story of mechanical solar systems, clocks, and English nobility

    CERN Document Server

    Buick, Tony

    2014-01-01

    To find the true story of the orrery, this book takes the reader to the vibrant, tumultous London of the 1600s. A mechanical model that shows the movements of the Moon and planets, the orrery takes its name from the Boyle family – the Earls of Orrery. Here is the fascinating story of the origins of this intricate device. Orreries are found everywhere. They appear in paintings, on the side of royal clocks, in stately home hallways, and of course, in museums all over the world. Scientific instruments to demonstrate the movements of the planets and predict their positions using measuring devices, they were devised largely by clockmakers, but many others played a role too and are given due credit. The story of the Boyles is not just relevant to a tiny corner of Ireland, but spans history. “Orrery” highlights the process of discovery and humankind’s universal fascination with the heavens, providing a fascinating example of the relationship between innovative thinking (invention) and precision enginee...

  6. Attutude-action consistency and social policy related to nuclear technology

    International Nuclear Information System (INIS)

    Lindell, M.K.; Perry, R.W.; Greene, M.

    1980-06-01

    This study reports the results of a further analysis of questionnaire data--parts of which have been previously reported by Lindell, Earle, Hebert and Perry (1978)--that are related to the issue of consistency of attitudes and behavior toward nuclear power and nuclear waste management. Three factors are considered that might be expected to have a significant bearing on attitude-action consistency: social support, attitude object importance and past activism. Analysis of the data indicated that pronuclear respondents were more likely to show consistency of attitudes and actions (66%) than were antinuclear respondents (51%) although the difference in proportions is not statistically significant. Further analyses showed a strong positive relation between attitude-action consistency and perceived social support, measured by the degree to which the respondent believed that close friends and work associated agreed with his attitude. This relationship held up even when controls for attitude object importance and past activism were introduced. Attitude object importance--the salience of the issue of energy shortage--had a statistically significant effect only when perceived social support was low. Past activism had no significant relation to attitude-action consistency. These data suggest that the level of active support for or opposition to nuclear technology will be affected by the distribution of favorable and unfavorable attitudes among residents of an area. Situations in which pro- and antinuclear attitudes are concentrated among members of interacting groups, rather than distributed randomly, are more likely to produce high levels of polarization

  7. “Soi-Disant Columbuses”: The Discovery of Dominica’s Boiling Lake and the Commodification of Knowledge in Colonial Societies

    Directory of Open Access Journals (Sweden)

    Lizabeth Paravisini-Gebert

    2008-12-01

    Full Text Available It may indeed be “a truth universally acknowledged” that “no man is an island, entire of itself.” Nonetheless, the entirety upon itself that Donne assumes as a given in connection to islands may be true only as far as geography and geometry are concerned – or perhaps, in the case of the poet, as far as the pure idea, the literary conceit, goes. The truth is that given the pernicious history of European colonization around the world, no island has retained its entirety of itself for very long after being “discovered” by Europeans. One may thus wonder if Donne himself was quite unaware of the irony implicit in his verses. In 1596, more than a quarter century before he penned his famous lines, he had had his own brush with conquest and colonization. In that year, he had enlisted in the Earl of Essex’s unsuccessful privateering expedition against Cadiz, and in 1597 he had sailed with Essex and Sir Walter Ralegh in the near-disastrous Islands Expedition, which had sought to intercept Spanish ships bringing gold and silver from South America as they sailed past the Azores.

  8. La revocación de disposiciones testamentarias en codicilos valencianos de los siglos XV y XVI

    Directory of Open Access Journals (Sweden)

    Jaime Piqueras Juan

    2013-11-01

    Full Text Available Se presenta en este artículo la investigación realizada sobre un tipo concreto de documentos de aplicación práctica del derecho relacionados con las sucesiones mortis causa, los codicilos. Sobre la base de un grupo de 30 codicilos valencianos de los siglos XV y primeros años del XVI, se sistematiza la orientación de las diversas modificaciones que estos documentos introdujeron sobre testamentos anteriores, de forma que es accesible la valoración de las cuestiones que resultaron de mayor interés para los testadores, apareciendo resultados que sugieren la idea de predominio de una mentalidad práctica por encima de las cuestiones directamente relacionadas con el mundo espiritual.Our research focuses on a particular type of document, the codicil, which involves a practical legal application of inheritance upon death. We use a group of thirty Valencian codicils of the fifteenth and earl ysixteenth centuries in order to categorize the manifold modifications that these documents introduced in previous wills. The result is a more accessible assessment of the issues that were of most interest to the testers, which leads one to suggest the idea of a practical mind-set prevailing over issues directly related to the spiritual realm.

  9. Hurricane Imaging Radiometer

    Science.gov (United States)

    Cecil, Daniel J.; Biswas, Sayak K.; James, Mark W.; Roberts, J. Brent; Jones, W. Linwood; Johnson, James; Farrar, Spencer; Sahawneh, Saleem; Ruf, Christopher S.; Morris, Mary; hide

    2014-01-01

    The Hurricane Imaging Radiometer (HIRAD) is a synthetic thinned array passive microwave radiometer designed to allow retrieval of surface wind speed in hurricanes, up through category five intensity. The retrieval technology follows the Stepped Frequency Microwave Radiometer (SFMR), which measures surface wind speed in hurricanes along a narrow strip beneath the aircraft. HIRAD maps wind speeds in a swath below the aircraft, about 50-60 km wide when flown in the lower stratosphere. HIRAD has flown in the NASA Genesis and Rapid Intensification Processes (GRIP) experiment in 2010 on a WB-57 aircraft, and on a Global Hawk unmanned aircraft system (UAS) in 2012 and 2013 as part of NASA's Hurricane and Severe Storms Sentinel (HS3) program. The GRIP program included flights over Hurricanes Earl and Karl (2010). The 2012 HS3 deployment did not include any hurricane flights for the UAS carrying HIRAD. The 2013 HS3 flights included one flight over the predecessor to TS Gabrielle, and one flight over Hurricane Ingrid. This presentation will describe the HIRAD instrument, its results from the 2010 and 2013 flights, and potential future developments.

  10. Lytton Strachey : l’historien intime de deux reines Lytton Strachey’s Intimate Biographies of Two Queens

    Directory of Open Access Journals (Sweden)

    Jeannine Hayat

    2007-01-01

    Full Text Available The British writer Lytton Strachey (1880-1932 wrote biographies of the two most eminent Queens of England: Queen Victoria (1921 and Elizabeth and Essex (1928. The two books made him a very famous historian. However, he would personally have preferred to be admired for his poetry or his plays, for he was a very gifted literary author. Nevertheless many of Strachey’s readers have appreciated his conception of biography, as a means of personal confession while studying the destiny of a public figure. Indeed the Stracheyan way of life, free from Victorian moral standards and guided by the rules of the Bloomsbury group, inspired his story of Victoria and Elizabeth. Both Queens at the end of their lives and at the height of their power carried on strange love affairs: Victoria with her Scottish gillie and Elizabeth with the Earl of Essex, thirty years her younger. In fact, both romances subtly reflect Strachey’s own love affairs. He was himself engaged in a kind of common life with Dora Carrington— the painter, thirteen years younger than him, with whom he was not sexually involved— while he engaged in numerous homosexual love affairs.

  11. Decision Science Perspectives on Hurricane Vulnerability: Evidence from the 2010–2012 Atlantic Hurricane Seasons

    Directory of Open Access Journals (Sweden)

    Kerry Milch

    2018-01-01

    Full Text Available Although the field has seen great advances in hurricane prediction and response, the economic toll from hurricanes on U.S. communities continues to rise. We present data from Hurricanes Earl (2010, Irene (2011, Isaac (2012, and Sandy (2012 to show that individual and household decisions contribute to this vulnerability. From phone surveys of residents in communities threatened by impending hurricanes, we identify five decision biases or obstacles that interfere with residents’ ability to protect themselves and minimize property damage: (1 temporal and spatial myopia, (2 poor mental models of storm risk, (3 gaps between objective and subjective probability estimates, (4 prior storm experience, and (5 social factors. We then discuss ways to encourage better decision making and reduce the economic and emotional impacts of hurricanes, using tools such as decision defaults (requiring residents to opt out of precautions rather than opt in and tailoring internet-based forecast information so that it is local, specific, and emphasizes impacts rather than probability.

  12. Analytic Reflected Lightcurves for Exoplanets

    Science.gov (United States)

    Haggard, Hal M.; Cowan, Nicolas B.

    2018-04-01

    The disk-integrated reflected brightness of an exoplanet changes as a function of time due to orbital and rotational motion coupled with an inhomogeneous albedo map. We have previously derived analytic reflected lightcurves for spherical harmonic albedo maps in the special case of a synchronously-rotating planet on an edge-on orbit (Cowan, Fuentes & Haggard 2013). In this letter, we present analytic reflected lightcurves for the general case of a planet on an inclined orbit, with arbitrary spin period and non-zero obliquity. We do so for two different albedo basis maps: bright points (δ-maps), and spherical harmonics (Y_l^m-maps). In particular, we use Wigner D-matrices to express an harmonic lightcurve for an arbitrary viewing geometry as a non-linear combination of harmonic lightcurves for the simpler edge-on, synchronously rotating geometry. These solutions will enable future exploration of the degeneracies and information content of reflected lightcurves, as well as fast calculation of lightcurves for mapping exoplanets based on time-resolved photometry. To these ends we make available Exoplanet Analytic Reflected Lightcurves (EARL), a simple open-source code that allows rapid computation of reflected lightcurves.

  13. The prevalence of inflammatory bowel diseases, microscopic colitis, and colorectal cancer in patients with irritable bowel syndrome

    Directory of Open Access Journals (Sweden)

    Magdy El-Salhy

    2011-07-01

    Full Text Available The diagnosis of irritable bowel syndrome (IBS is symptom-based and experts have developed diagnostic criteria for IBS. Distinguishing inflammatory bowel diseases (IBD from IBS, especially with mild disease activity, can be difficult. Another concern is microscopic colitis (MC. MC and IBS have similar symptoms and a normal endoscopic appearance. Our study investigated the prevalence of patients with IBD, MC, and colorectal cancer among 968 patients that fulfill the Rome III criteria for IBS. Among these patients, four were found with IBD (0.4% and seven with MC (0.7%. Among the IBD patients, three suffered from Crohn’s disease, affecting the terminal ileum, and one with ulcerative rectosigmoiditis. Of the seven patients with MC, two had collagenous colitis and five had lymphocytic colitis. Two IBS diarrhea-predominant patients had adenocarcin­oma in the sigmoid colon. These patients were a female aged 58 years and a male aged 56 years. We concluded from our study and earl­ier studies that symptom-based diagnosis of IBS may lead to missing a number of other gastrointestinal disorders that require quite different management than that for IBS.

  14. Experimental study on active specific immunotherapy utilizing the immune reaction of low-dose irradiated tumor tissue, 8

    International Nuclear Information System (INIS)

    Imanaka, Kazufumi; Gose, Kyuhei; Ichiyanagi, Akihiro

    1983-01-01

    The effectiveness of active specific immunotherapy prepared from a low-dose irradiated tumor tissue has already reported. The present study was designed to investigate the effect of Mitomycin C-treated active specific immunotherapy. Twelve-week-aged female C3H/He mice transplanted with MM 46 tumors were exposed to local electron radiotherapy with a dose of 3,000 rad on the 5th day after tumor inoculation. Tumor cells prepared for active specific immunotherapy were pretreated with Mitomycin C at concentration of 20 μg/10 7 cells in Eagle MEM Earle containing 100 IU/ml penicillin. The cell suspension was incubated at 37 0 C for 15 minutes. Mitomycin C-treated active specific immunotherapy was performed on the 12th day. Antitumor effect was evaluated by the regression of the tumor and survival curve. The remarkable regression of the tumor and significant elongation of the survival period were observed in the group which received Mitomycin C-treated active specific immunotherapy and the group which received active specific immunotherapy without the treatment of Mitomycin C. (author)

  15. Exploring cell apoptosis and senescence to understand and treat cancer: an interview with Scott Lowe.

    Science.gov (United States)

    Lowe, Scott; Cifra, Alessandra

    2015-11-01

    Scott W. Lowe is currently principal investigator at the Memorial Sloan-Kettering Cancer Center. After beginning his studies in chemical engineering, he decided to take another path and became fascinated by biochemistry, genetics and molecular biology, which ultimately led to an interest in human disease, particularly cancer. During his PhD at the Massachusetts Institute of Technology (MIT), Scott had the opportunity to benefit from the exceptional mentorship of Earl Ruley, David Housman and Tyler Jacks, and contributed to elucidating how the p53 (TP53) tumor suppressor gene limits oncogenic transformation and modulates the cytotoxic response to conventional chemotherapy. This important work earned him a fellowship from the Cold Spring Harbor Laboratory, which helped to launch his independent career. Scott is now a leading scientist in the cancer field and his work has helped to shed light on mechanisms of cell apoptosis and senescence to better understand and treat cancer. In this interview, he talks about this incredible scientific journey. © 2015. Published by The Company of Biologists Ltd.

  16. Alteration of Depressive-like Behaviors by Psilocybe cubensis Alkaloid Extract in Mice: the Role of Glutamate Pathway

    Directory of Open Access Journals (Sweden)

    Elaheh Mahmoudi

    2018-03-01

    Full Text Available Background and objectives: Considering the increasing prevalence of depression, many studies are launched to investigate new antidepressant treatments. The present research has shown how psilocybin as an active compound of Psilocybe cubensis (Earle Singer extract (PCE can change the parameters related to depression and anxiety in animal models. Both serotonin (5-hydroxytryptamine: 5-HT and glutamate modulate depressive-like behaviors and, therefore, we examined the possible interaction of psilocybin as 5-HT1 agonist with glutamate receptor N-methyl-D-aspartate (NMDA. Methods: Psilocybe cubensis extract of this mushroom was prepared by ethyl acetate. NMRI mice involved in all experiments and were treated with the vehicle, extract, or standard drug intraperitoneally. Open field (OFT, forced swimming (FST and tail suspension tests (TST were applied to measure the intended parameters. OFT was performed to verify the applied doses for measuring the following antidepressant activity.  Results: PCE at the doses of 100 mg/kg significantly changed the locomotion, time spent in center and velocity of the animals in OFT. While treatment of the animals with PCE 10 and 40 mg/kg or ketamine 1 mg/kg did not alter the locomotor activity, co-administration of these subeffective amounts significantly reduced the immobility time in both FST and TST. Conclusion: These effects may indicate possible implication of psilocybin with NMDA receptor which consequently produces the antidepressant effects.

  17. Influence of cell culture medium composition on in vitro dissolution behavior of a fluoride-containing bioactive glass.

    Science.gov (United States)

    Shah, Furqan A; Brauer, Delia S; Wilson, Rory M; Hill, Robert G; Hing, Karin A

    2014-03-01

    Bioactive glasses are used clinically for bone regeneration, and their bioactivity and cell compatibility are often characterized in vitro, using physiologically relevant test solutions. The aim of this study was to show the influence of varying medium characteristics (pH, composition, presence of proteins) on glass dissolution and apatite formation. The dissolution behavior of a fluoride-containing bioactive glass (BG) was investigated over a period of one week in Eagle's Minimal Essential Medium with Earle's Salts (MEM), supplemented with either, (a) acetate buffer, (b) 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffer, (c) HEPES + carbonate, or (d) HEPES + carbonate + fetal bovine serum. Results show pronounced differences in pH, ion release, and apatite formation over 1 week: Despite its acidic pH (pH 5.8 after BG immersion, as compared to pH 7.4-8.3 for HEPES-containing media), apatite formation was fastest in acetate buffered (HEPES-free) MEM. Presence of carbonate resulted in formation of calcite (calcium carbonate). Presence of serum proteins, on the other hand, delayed apatite formation significantly. These results confirm that the composition and properties of a tissue culture medium are important factors during in vitro experiments and need to be taken into consideration when interpreting results from dissolution or cell culture studies. Copyright © 2013 Wiley Periodicals, Inc.

  18. Quantification, improvement, and harmonization of small lesion detection with state-of-the-art PET

    Energy Technology Data Exchange (ETDEWEB)

    Vos, Charlotte S. van der [Radboud University Medical Centre, Department of Radiology and Nuclear Medicine, Nijmegen (Netherlands); University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Enschede (Netherlands); Koopman, Danielle [University of Twente, MIRA Institute for Biomedical Technology and Technical Medicine, Enschede (Netherlands); Isala Hospital, Department of Nuclear Medicine, Zwolle (Netherlands); Rijnsdorp, Sjoerd; Arends, Albert J. [Catharina Hospital, Department of Medical Physics, Eindhoven (Netherlands); Boellaard, Ronald [University of Groningen, University Medical Centre Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); VU University Medical Center, Department of Radiology and Nuclear Medicine, Amsterdam (Netherlands); Dalen, Jorn A. van [Isala Hospital, Department of Nuclear Medicine, Zwolle (Netherlands); Isala, Department of Medical Physics, Zwolle (Netherlands); Lubberink, Mark [Uppsala University, Department of Surgical Sciences, Uppsala (Sweden); Uppsala University Hospital, Department of Medical Physics, Uppsala (Sweden); Willemsen, Antoon T.M. [University of Groningen, University Medical Centre Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen (Netherlands); Visser, Eric P. [Radboud University Medical Centre, Department of Radiology and Nuclear Medicine, Nijmegen (Netherlands)

    2017-08-15

    In recent years, there have been multiple advances in positron emission tomography/computed tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT scanners introduces new hardware, software, and acquisition methods. This review describes these new developments, which include time-of-flight (TOF), point-spread-function (PSF), maximum-a-posteriori (MAP) based reconstruction, smaller voxels, respiratory gating, metal artefact reduction, and administration of quadratic weight-dependent {sup 18}F-fluorodeoxyglucose (FDG) activity. Also, hardware developments such as continuous bed motion (CBM), (digital) solid-state photodetectors and combined PET and magnetic resonance (MR) systems are explained. These novel techniques have a significant impact on cancer imaging, as they result in better image quality, improved small lesion detectability, and more accurate quantification of radiopharmaceutical uptake. This influences cancer diagnosis and staging, as well as therapy response monitoring and radiotherapy planning. Finally, the possible impact of these developments on the European Association of Nuclear Medicine (EANM) guidelines and EANM Research Ltd. (EARL) accreditation for FDG-PET/CT tumor imaging is discussed. (orig.)

  19. Sonnets and psalm

    Science.gov (United States)

    Mobley, Aaron

    Sonnets and Psalm investigates the relationships between the sacred nature of Psalm 91 and the secular nature of two sonnets, William Shakespeare's Sonnet 73 and Henry Howard, Earl of Surrey's Sonnet 8. Sonnets and Psalm exploits a dynamic that arises from the juxtaposition of disparate musical universes, choral and instrumental, and the unique and, at times, ineffable aesthetic qualities that emerge as a result of the intentional ordering of musical language and block structures. In a five movement form the listener is guided from vocal events painted on orchestral palettes, to solely instrumental movements, and back again. While the movements can stand independently of each other, there are ponderous transformations of material within and throughout the piece that create a thread that functions as a consistent generative unifying element. A recurrent utilization of motive, color, register, pitch-specific sonorities and gesture, enhances the unity of the work while exploiting the contradistinctive nature of each movement. Relational aspects of hidden and transformed materials from the Psalm and the sonnets (including the Mosaic movements) that are present throughout create a forward and back-relating dynamic. There is a programmatic element at work as well that in itself is a statement: after the sonnets and the mosaics, the listener is finally presented with the Psalm, a conclusion.

  20. Identification of QTLs for resistance to powdery mildew and SSR markers diagnostic for powdery mildew resistance genes in melon (Cucumis melo L.).

    Science.gov (United States)

    Fukino, Nobuko; Ohara, Takayoshi; Monforte, Antonio J; Sugiyama, Mitsuhiro; Sakata, Yoshiteru; Kunihisa, Miyuki; Matsumoto, Satoru

    2008-12-01

    Powdery mildew caused by Podosphaera xanthii is an important foliar disease in melon. To find molecular markers for marker-assisted selection, we constructed a genetic linkage map of melon based on a population of 93 recombinant inbred lines derived from crosses between highly resistant AR 5 and susceptible 'Earl's Favourite (Harukei 3)'. The map spans 877 cM and consists of 167 markers, comprising 157 simple sequence repeats (SSRs), 7 sequence characterized amplified region/cleavage amplified polymorphic sequence markers and 3 phenotypic markers segregating into 20 linkage groups. Among them, 37 SSRs and 6 other markers were common to previous maps. Quantitative trait locus (QTL) analysis identified two loci for resistance to powdery mildew. The effects of these QTLs varied depending on strain and plant stage. The percentage of phenotypic variance explained for resistance to the pxA strain was similar between QTLs (R (2) = 22-28%). For resistance to pxB strain, the QTL on linkage group (LG) XII was responsible for much more of the variance (41-46%) than that on LG IIA (12-13%). The QTL on LG IIA was located between two SSR markers. Using an independent population, we demonstrated the effectiveness of these markers. This is the first report of universal and effective markers linked to a gene for powdery mildew resistance in melon.

  1. Global earthquake casualties due to secondary effects: A quantitative analysis for improving rapid loss analyses

    Science.gov (United States)

    Marano, K.D.; Wald, D.J.; Allen, T.I.

    2010-01-01

    This study presents a quantitative and geospatial description of global losses due to earthquake-induced secondary effects, including landslide, liquefaction, tsunami, and fire for events during the past 40 years. These processes are of great importance to the US Geological Survey's (USGS) Prompt Assessment of Global Earthquakes for Response (PAGER) system, which is currently being developed to deliver rapid earthquake impact and loss assessments following large/significant global earthquakes. An important question is how dominant are losses due to secondary effects (and under what conditions, and in which regions)? Thus, which of these effects should receive higher priority research efforts in order to enhance PAGER's overall assessment of earthquakes losses and alerting for the likelihood of secondary impacts? We find that while 21.5% of fatal earthquakes have deaths due to secondary (non-shaking) causes, only rarely are secondary effects the main cause of fatalities. The recent 2004 Great Sumatra-Andaman Islands earthquake is a notable exception, with extraordinary losses due to tsunami. The potential for secondary hazards varies greatly, and systematically, due to regional geologic and geomorphic conditions. Based on our findings, we have built country-specific disclaimers for PAGER that address potential for each hazard (Earle et al., Proceedings of the 14th World Conference of the Earthquake Engineering, Beijing, China, 2008). We will now focus on ways to model casualties from secondary effects based on their relative importance as well as their general predictability. ?? Springer Science+Business Media B.V. 2009.

  2. Quantification, improvement, and harmonization of small lesion detection with state-of-the-art PET

    International Nuclear Information System (INIS)

    Vos, Charlotte S. van der; Koopman, Danielle; Rijnsdorp, Sjoerd; Arends, Albert J.; Boellaard, Ronald; Dalen, Jorn A. van; Lubberink, Mark; Willemsen, Antoon T.M.; Visser, Eric P.

    2017-01-01

    In recent years, there have been multiple advances in positron emission tomography/computed tomography (PET/CT) that improve cancer imaging. The present generation of PET/CT scanners introduces new hardware, software, and acquisition methods. This review describes these new developments, which include time-of-flight (TOF), point-spread-function (PSF), maximum-a-posteriori (MAP) based reconstruction, smaller voxels, respiratory gating, metal artefact reduction, and administration of quadratic weight-dependent 18 F-fluorodeoxyglucose (FDG) activity. Also, hardware developments such as continuous bed motion (CBM), (digital) solid-state photodetectors and combined PET and magnetic resonance (MR) systems are explained. These novel techniques have a significant impact on cancer imaging, as they result in better image quality, improved small lesion detectability, and more accurate quantification of radiopharmaceutical uptake. This influences cancer diagnosis and staging, as well as therapy response monitoring and radiotherapy planning. Finally, the possible impact of these developments on the European Association of Nuclear Medicine (EANM) guidelines and EANM Research Ltd. (EARL) accreditation for FDG-PET/CT tumor imaging is discussed. (orig.)

  3. Development of the nuclear weapons complex EP architecture

    Energy Technology Data Exchange (ETDEWEB)

    Murray, C.; Halbleib, L.

    1996-07-01

    The Nuclear Weapons Guidance Team is an interagency committee led by Earl Whiteman, DOE that chartered the generation of EP40100, Concurrent Qualification and its successor EP401099, Concurrent Engineering and Qualification. As this new philosophy of concurrent operations has evolved and as implementation has been initiated, conflicts and insufficiencies in the remaining Engineering Procedures (EPs) have become more apparent. At the Guidance Team meeting in November 1995, this issue was explored and several approaches were considered. It was concluded at this meeting, that a smaller set of interagency EPs described in a hierarchical system could provide the necessary interagency direction to support complex-wide implementation. This set consolidates many existing EP processes where consistency and commonality are critical to success of the extended enterprise. The Guidance Team subsequently chartered an interagency team to initiate development activity associated with the envisioned new EP set. This team had participation from seven Nuclear Weapons Complex (NWC) sites as well as DOE/AL and DP-14 (team members are acknowledged later in this report). Per the Guidance Team, this team, referred to as the Architecture Subcommittee, was to map out and define an EP Architecture for the interagency EPs, make recommendations regarding a more agile process for EP approval and suggest an aggressive timeline to develop the combined EPs. The Architecture Subcommittee was asked to brief their output at the February Guidance Team meeting. This SAND report documents the results of the Architecture Subcommittee`s recommendations.

  4. Lectures on quasiconformal mappings

    CERN Document Server

    Ahlfors, Lars V

    2006-01-01

    Lars Ahlfors's Lectures on Quasiconformal Mappings, based on a course he gave at Harvard University in the spring term of 1964, was first published in 1966 and was soon recognized as the classic it was shortly destined to become. These lectures develop the theory of quasiconformal mappings from scratch, give a self-contained treatment of the Beltrami equation, and cover the basic properties of Teichm�ller spaces, including the Bers embedding and the Teichm�ller curve. It is remarkable how Ahlfors goes straight to the heart of the matter, presenting major results with a minimum set of prerequisites. Many graduate students and other mathematicians have learned the foundations of the theories of quasiconformal mappings and Teichm�ller spaces from these lecture notes. This edition includes three new chapters. The first, written by Earle and Kra, describes further developments in the theory of Teichm�ller spaces and provides many references to the vast literature on Teichm�ller spaces and quasiconformal ...

  5. The Impact of High-Profile Sexual Abuse Cases in the Media on a Pediatric Emergency Department.

    Science.gov (United States)

    Flannery, Dustin D; Stephens, Clare L; Thompson, Amy D

    2016-01-01

    High-profile media cases of sexual abuse may encourage disclosures of abuse from victims of unrelated assaults and also influence parental concerns, leading to increased emergency department visits. In the region of the study authors' institution, there are two recent high-profile sexual abuse cases with media coverage: Earl Bradley, a Delaware pediatrician, and Jerry Sandusky, a Pennsylvania college football coach. This is a retrospective cohort study of children evaluated for sexual abuse at a pediatric emergency department. Patients were classified as either presenting during a media period or non-media period. The media periods were one-month periods immediately following breaking news reports, when the cases were highly publicized in the media. The non-media periods were the 12-month periods directly preceding the first reports. The median number of emergency department visits per month during a non-media period was 9 visits (interquartile range 6-10). There were 11 visits in the month following the Sandusky case and 13 visits following the Bradley case. There was no statistical difference in number of emergency department visits for sexual abuse between the periods (p = .09). These finding have implications regarding use of resources in pediatric EDs after high-profile sexual abuse cases.

  6. Magnesium alloys: predicting in vivo corrosion with in vitro immersion testing.

    Science.gov (United States)

    Walker, Jemimah; Shadanbaz, Shaylin; Kirkland, Nicholas T; Stace, Edward; Woodfield, Tim; Staiger, Mark P; Dias, George J

    2012-05-01

    Magnesium (Mg) and its alloys have been proposed as degradable replacements to commonly used orthopedic biomaterials such as titanium alloys and stainless steel. However, the corrosion of Mg in a physiological environment remains a difficult characteristic to accurately assess with in vitro methods. The aim of this study was to identify a simple in vitro immersion test that could provide corrosion rates similar to those observed in vivo. Pure Mg and five alloys (AZ31, Mg-0.8Ca, Mg-1Zn, Mg-1Mn, Mg-1.34Ca-3Zn) were immersed in either Earle's balanced salt solution (EBSS), minimum essential medium (MEM), or MEM-containing 40 g/L bovine serum albumin (MEMp) for 7, 14, or 21 days before removal and assessment of corrosion by weight loss. This in vitro data was compared to in vivo corrosion rates of the same materials implanted in a subcutaneous environment in Lewis rats for equivalent time points. The results suggested that, for the alloys investigated, the EBSS buffered with sodium bicarbonate provides a rate of degradation comparable to those observed in vivo. In contrast, the addition of components such as (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) (HEPES), vitamins, amino acids, and albumin significantly increased corrosion rates. Based on these findings, it is proposed that with this in vitro protocol, immersion of Mg alloys in EBSS can be used as a predictor of in vivo corrosion. Copyright © 2012 Wiley Periodicals, Inc.

  7. Ketoconazole inhibits the growth and development of Ichthyophonus sp. (Mesomycetozoa) in vitro.

    Science.gov (United States)

    Hontoria, Francisco; González, M Angeles; Sitjà-Bobadilla, Ariadna; Palenzuela, Oswaldo; Alvarez-Pellitero, Pilar

    2009-01-01

    We determined the in vitro effect of the azol-derivative antifungal ketoconazole (KZ) on the morphology, growth, and development of teleost fish parasite Ichthyophonus sp. The KZ was delivered to culture medium using liposomes (L) or a lipid emulsion (E) at five different doses (i.e. 5, 50, 100, 200, and 400 microg/ml) for both L and E formulations. Controls consisted of Eagle's minimum essential medium (MEM) supplemented with 10% foetal bovine serum (MEM-10) alone (C-MEM) or containing amounts of L or E equivalent to those used in the KZ100 and KZ400 treatments (i.e. 100L, 400L, 100E, and 400E, respectively). Morphological alterations, such as a decrease in the number of dividing spores and nuclei, and condensation or even destruction of the cytoplasm, were observed using light and electron microscopy in the MEM-cultured organisms receiving KZ formulations, especially with KZ400L preparations, at both 7- and 14-d postinoculation. The KZ treatments also demonstrated a statistically significant inhibition of Ichthyophonus growth in MEM. These treatments also had an inhibitory effect on subsequent Ichthyophonus germination in Earle's fish saline agar (EFSA) medium, which was more evident for L formulations when the organism was treated for 7 d and for E formulations at 14 d. Our results endorse the potential use of KZ for the treatment for ichthyophonosis and provide support to proceed to in vivo assays.

  8. Generality of a congruity effect in judgements of relative order.

    Science.gov (United States)

    Liu, Yang S; Chan, Michelle; Caplan, Jeremy B

    2014-10-01

    The judgement of relative order (JOR) procedure is used to investigate serial-order memory. Measuring response times, the wording of the instructions (whether the earlier or the later item was designated as the target) reversed the direction of search in subspan lists (Chan, Ross, Earle, & Caplan Psychonomic Bulletin & Review, 16(5), 945-951, 2009). If a similar congruity effect applied to above-span lists and, furthermore, with error rate as the measure, this could suggest how to model order memory across scales. Participants performed JORs on lists of nouns (Experiment 1: list lengths = 4, 6, 8, 10) or consonants (Experiment 2: list lengths = 4, 8). In addition to the usual distance, primacy, and recency effects, instructions interacted with serial position of the later probe in both experiments, not only in response time, but also in error rate, suggesting that availability, not just accessibility, is affected by instructions. The congruity effect challenges current memory models. We fitted Hacker's (Journal of Experimental Psychology: Human Learning and Memory, 6(6), 651-675, 1980) self-terminating search model to our data and found that a switch in search direction could explain the congruity effect for short lists, but not longer lists. This suggests that JORs may need to be understood via direct-access models, adapted to produce a congruity effect, or a mix of mechanisms.

  9. Reduced telomere length is not associated with early signs of vascular aging in young men born after intrauterine growth restriction: a paradox?

    DEFF Research Database (Denmark)

    Laganovic, M.; Bendix, L.; Rubelj, I.

    2014-01-01

    Objective: The mechanisms that increase cardiovascular risk in individuals born small for gestational age (SGA) are not well understood. Telomere shortening has been suggested to be a predictor of disease onset. Our aim was to determine whether impaired intrauterine growth is associated with earl...... of cardiovascular risk in SGA participants. Follow-up of this cohort will clarify hypothesis and validate telomere dynamics as indicators of future health risks.......Objective: The mechanisms that increase cardiovascular risk in individuals born small for gestational age (SGA) are not well understood. Telomere shortening has been suggested to be a predictor of disease onset. Our aim was to determine whether impaired intrauterine growth is associated with early......IMT, and a trend to increased SBP and heart rate in comparison to the AGA group. Interestingly, SGA men exhibited a 42% longer LTL than the AGA group. LTL was inversely associated with age, BMI, BP and birth parameters. In multiple regression analysis, BMI was the key determinant of SBP and cIMT. Conclusion: Young...

  10. Thomas Birch's ‘Weekly Letter’ (1741–66): correspondence and history in the mid-eighteenth-century Royal Society

    Science.gov (United States)

    Ellis, Markman

    2014-01-01

    Thomas Birch (1705–66), Secretary of the Royal Society from 1752 to 1765, and Philip Yorke, second Earl of Hardwicke (1720–90), wrote a ‘Weekly Letter’ from 1741 to 1766, an unpublished correspondence of 680 letters now housed in the British Library (Additional Mss 35396–400). The article examines the dimensions and purposes of this correspondence, an important conduit of information for the influential coterie of the ‘Hardwicke circle’ gathered around Yorke in the Royal Society. It explores the writers' self-conception of the correspondence, which was expressed in deliberately archaic categories of seventeenth-century news exchange, such as the newsletter, aviso and a-la-main. It shows how the letter writers negotiated their difference in status through the discourse of friendship, and concludes that the ‘Weekly Letter’ constituted for the correspondents a form of private knowledge, restricted in circulation to their discrete group, and as such unlike the open and networked model of Enlightenment science. PMID:25254279

  11. Hurricane Imaging Radiometer (HIRAD) Wind Speed Retrievals and Assessment Using Dropsondes

    Science.gov (United States)

    Cecil, Daniel J.; Biswas, Sayak K.

    2018-01-01

    The Hurricane Imaging Radiometer (HIRAD) is an experimental C-band passive microwave radiometer designed to map the horizontal structure of surface wind speed fields in hurricanes. New data processing and customized retrieval approaches were developed after the 2015 Tropical Cyclone Intensity (TCI) experiment, which featured flights over Hurricanes Patricia, Joaquin, Marty, and the remnants of Tropical Storm Erika. These new approaches produced maps of surface wind speed that looked more realistic than those from previous campaigns. Dropsondes from the High Definition Sounding System (HDSS) that was flown with HIRAD on a WB-57 high altitude aircraft in TCI were used to assess the quality of the HIRAD wind speed retrievals. The root mean square difference between HIRAD-retrieved surface wind speeds and dropsonde-estimated surface wind speeds was 6.0 meters per second. The largest differences between HIRAD and dropsonde winds were from data points where storm motion during dropsonde descent compromised the validity of the comparisons. Accounting for this and for uncertainty in the dropsonde measurements themselves, we estimate the root mean square error for the HIRAD retrievals as around 4.7 meters per second. Prior to the 2015 TCI experiment, HIRAD had previously flown on the WB-57 for missions across Hurricanes Gonzalo (2014), Earl (2010), and Karl (2010). Configuration of the instrument was not identical to the 2015 flights, but the methods devised after the 2015 flights may be applied to that previous data in an attempt to improve retrievals from those cases.

  12. Hurricane Imaging Radiometer Wind Speed and Rain Rate Retrievals during the 2010 GRIP Flight Experiment

    Science.gov (United States)

    Sahawneh, Saleem; Farrar, Spencer; Johnson, James; Jones, W. Linwood; Roberts, Jason; Biswas, Sayak; Cecil, Daniel

    2014-01-01

    Microwave remote sensing observations of hurricanes, from NOAA and USAF hurricane surveillance aircraft, provide vital data for hurricane research and operations, for forecasting the intensity and track of tropical storms. The current operational standard for hurricane wind speed and rain rate measurements is the Stepped Frequency Microwave Radiometer (SFMR), which is a nadir viewing passive microwave airborne remote sensor. The Hurricane Imaging Radiometer, HIRAD, will extend the nadir viewing SFMR capability to provide wide swath images of wind speed and rain rate, while flying on a high altitude aircraft. HIRAD was first flown in the Genesis and Rapid Intensification Processes, GRIP, NASA hurricane field experiment in 2010. This paper reports on geophysical retrieval results and provides hurricane images from GRIP flights. An overview of the HIRAD instrument and the radiative transfer theory based, wind speed/rain rate retrieval algorithm is included. Results are presented for hurricane wind speed and rain rate for Earl and Karl, with comparison to collocated SFMR retrievals and WP3D Fuselage Radar images for validation purposes.

  13. One hundred years of instrumental phonetic fieldwork on North America Indian languages

    Science.gov (United States)

    McDonough, Joyce

    2005-04-01

    A resurgence of interest in phonetic fieldwork on generally morphologically complex North American Indian languages over the last 15 years is a continuation of a tradition started a century ago with the Earle Pliny Goddard, who collected kymographic and palatographic field-data between 1906-1927 on several Athabaskan languages: Coastal Athabaskan (Hupa and Kato), Apachean (Mescalero, Jicarilla, White Mountain, San Juan Carlos Apache), and several Athabaskan languages in Northern Canada (Cold Lake and Beaver); data that remains important for its record of segmental timing profiles and rare articulatory documentation in then largely monolingual communities. This data in combination with new work has resulted in the emergence of a body of knowledge of these typologically distinct families that often challenge notions of phonetic universality and typology. Using the Athabaskan languages as benchmark example and starting with Goddard's work, two types of emergent typological patterns will be discussed; the persistence of fine-grained timing and duration details across the widely dispersed family, and the broad variation in prosodic types that exists, both of which are unaccounted for by phonetic or phonological theories.

  14. BAG3 promoted starvation-induced apoptosis of thyroid cancer cells via attenuation of autophagy.

    Science.gov (United States)

    Li, Si; Zhang, Hai-Yan; Wang, Tian; Meng, Xin; Zong, Zhi-Hong; Kong, De-Hui; Wang, Hua-Qin; Du, Zhen-Xian

    2014-11-01

    BAG3 plays a regulatory role in a number of cellular processes. Recent studies have attracted much attention on its role in activation of selective autophagy. In addition, we have very recently reported that BAG3 is implicated in a BECN1-independent autophagy, namely noncanonical autophagy. The current study aimed to investigate the potential involvement of BAG3 in canonical autophagy triggered by Earle's Balanced Salt Solution (EBSS) starvation. Replacement of complete medium with EBSS was used to trigger canonical autophagy. BAG3 expression was measured using real-time RT-PCR and Western blot. Autophagy was monitored using LC3-II transition and p62/SQSTM1 accumulation by Western blot, as well as punctate distribution of LC3 by immunofluorescence staining. Cell growth and apoptotic cell death was investigated using real-time cell analyzer and flowcytometry, respectively. BAG3 expression was potently reduced by EBSS starvation. Forced expression of BAG3 suppressed autophagy and promoted apoptotic cell death of thyroid cancer cells elicited by starvation. In addition, in the presence of autophagy inhibitor, the enhancing effect of BAG3 on apoptotic cell death was attenuated. These results suggest that BAG3 promotes apoptotic cell death in starved thyroid cancer cells, at least in part by autophagy attenuation.

  15. One physical educator's career cycle: strong start, great run, approaching finish.

    Science.gov (United States)

    Woods, Amelia Mays; Lynn, Susan K

    2014-03-01

    This article is nested within a longitudinal project examining 6 teachers' journeys along their career cycles (Lynn & Woods, 2010; Woods & Earls, 1995; Woods & Lynn, 2001). Two participants from the initial 6 continue to teach K-12 physical education; 1 of these participants, Everett, is examined in the current study. This veteran teacher's career-cycle movement and the environmental factors that both enhanced and constrained his career development are examined through the lens of Fessler and Christensen's career cycle model (1992). Data sources included: 8 formal interviews with Everett; formal interviews with his university teacher educators, student-teacher supervisor, principal, and spouse; informal interviews; field notes; and systematic teaching observations. An interpretative framework was used to assess the perceptions and meanings Everett gave to experiences as a physical educator and coach. Several factors acutely influenced Everett's career progression, including: (a) his individual disposition, (b) the impact and continued influence of a professional preparation program, and (c) his school and community support. He entered the profession with great promise and spent most of his career in the enthusiastic and growing, and the career stability, stages before shifting into the career frustration stage where he currently remains. Everett was able to negotiate personal and organizational environmental factors that have been identified as barriers for some physical educators. Therefore, viewing his professional life through the lens of the career cycle provides insights into the areas of change necessary to motivate and retain high-quality physical educators such as Everett.

  16. Maintenance of cAMP in non-heart-beating donor lungs reduces ischemia-reperfusion injury.

    Science.gov (United States)

    Hoffmann, S C; Bleiweis, M S; Jones, D R; Paik, H C; Ciriaco, P; Egan, T M

    2001-06-01

    Studies suggest that pulmonary vascular ischemia-reperfusion injury (IRI) can be attenuated by increasing intracellular cAMP concentrations. The purpose of this study was to determine the effect of IRI on capillary permeability, assessed by capillary filtration coeficient (Kfc), in lungs retrieved from non-heart-beating donors (NHBDs) and reperfused with the addition of the beta(2)-adrenergic receptor agonist isoproterenol (iso), and rolipram (roli), a phosphodiesterase (type IV) inhibitor. Using an in situ isolated perfused lung model, lungs were retrieved from NHBD rats at varying intervals after death and either ventilated with O(2) or not ventilated. The lungs were reperfused with Earle's solution with or without a combination of iso (10 microM) and roli (2 microM). Kfc, lung viability, and pulmonary hemodynamics were measured. Lung tissue levels of adenine nucleotides and cAMP were measured by HPLC. Combined iso and roli (iso/roli) reperfusion decreased Kfc significantly (p Kfc in non-iso/roli-reperfused (r = 0.89) and iso/roli-reperfused (r = 0.97) lungs. cAMP levels correlated with Kfc (r = 0.93) in iso/roli-reperfused lungs. Pharmacologic augmentation of tissue TAN and cAMP levels might ameliorate the increased capillary permeability observed in lungs retrieved from NHBDs.

  17. Pulmonary preservation studies: effects on endothelial function and pulmonary adenine nucleotides.

    Science.gov (United States)

    Paik, Hyo Chae; Hoffmann, Steven C; Egan, Thomas M

    2003-02-27

    Lung transplantation is an effective therapy plagued by a high incidence of early graft dysfunction, in part because of reperfusion injury. The optimal preservation solution for lung transplantation is unknown. We performed experiments using an isolated perfused rat lung model to test the effect of lung preservation with three solutions commonly used in clinical practice. Lungs were retrieved from Sprague-Dawley rats and flushed with one of three solutions: modified Euro-Collins (MEC), University of Wisconsin (UW), or low potassium dextran and glucose (LPDG), then stored cold for varying periods before reperfusion with Earle's balanced salt solution using the isolated perfused rat lung model. Outcome measures were capillary filtration coefficient (Kfc), wet-to-dry weight ratio, and lung tissue levels of adenine nucleotides and cyclic AMP. All lungs functioned well after 4 hr of storage. By 6 hr, UW-flushed lungs had a lower Kfc than LPDG-flushed lungs. After 8 hr of storage, only UW-flushed lungs had a measurable Kfc. Adenine nucleotide levels were higher in UW-flushed lungs after prolonged storage. Cyclic AMP levels correlated with Kfc in all groups. Early changes in endothelial permeability seemed to be better attenuated in lungs flushed with UW compared with LPDG or MEC; this was associated with higher amounts of adenine nucleotides. MEC-flushed lungs failed earlier than LPDG-flushed or UW-flushed lungs. The content of the solution may be more important for lung preservation than whether the ionic composition is intracellular or extracellular.

  18. [Protective effect of pretreatment of Salvia miltiorrhiza Bunge. f. alba plasma against oxygen-glucose deprivation-induced injury of cultured rat hippocampal neurons by inhibiting apoptosis].

    Science.gov (United States)

    Li, Mei-Yi; Zhang, Yan-Bo; Zuo, Huan; Liu, Li-Li; Niu, Jing-Zhong

    2012-02-25

    The present study was to investigate the effect of Salvia miltiorrhiza Bunge. f. alba (SMA) pharmacological pretreatment on apoptosis of cultured hippocampal neurons from neonate rats under oxygen-glucose deprivation (OGD). Cultured hippocampal neurons were randomly divided into five groups (n = 6): normal plasma group, low dose SMA plasma (2.5%) group, middle dose SMA plasma (5%) group, high dose SMA plasma (10%) group and control group. The hippocampal neurons were cultured and treated with plasma from adult Wistar rats intragastrically administered with saline or aqueous extract of SMA. The apoptosis of neurons was induced by glucose-free Earle's solution containing 1 mmol/L Na2S2O4 and labeled by MTT and Annexin V/PI double staining. Moreover, protein expressions of Bcl-2 and Bax were detected by immunofluorescence. The results showed that few apoptotic cells were observed in control group, whereas the number of apoptotic cells was greatly increased in normal plasma group and low dose SMA plasma group. Both middle and high dose SMA plasma could protect cultured hippocampal neurons from apoptosis induced by OGD (P control, normal plasma and low dose SMA plasma groups, middle and high dose SMA plasma groups both showed significantly higher levels of Bcl-2 (P neurons by up-regulating the expression of Bcl-2 and down-regulating the expression of Bax.

  19. [Lessening effect of hypoxia-preconditioned rat cerebrospinal fluid on oxygen-glucose deprivation-induced injury of cultured hippocampal neurons in neonate rats and possible mechanism].

    Science.gov (United States)

    Niu, Jing-Zhong; Zhang, Yan-Bo; Li, Mei-Yi; Liu, Li-Li

    2011-12-25

    The present study was to investigate the effect of cerebrospinal fluid (CSF) from the rats with hypoxic preconditioning (HPC) on apoptosis of cultured hippocampal neurons in neonate rats under oxygen glucose deprivation (OGD). Adult Wistar rats were exposed to 3 h of hypoxia for HPC, and then their CSF was taken out. Cultured hippocampal neurons from the neonate rats were randomly divided into four groups (n = 6): normal control group, OGD group, normal CSF group and HPC CSF group. OGD group received 1.5 h of incubation in glucose-free Earle's solution containing 1 mmol/L Na2S2O4, and normal and HPC CSF groups were subjected to 1 d of corresponding CSF treatments followed by 1.5 h OGD. The apoptosis of neurons was analyzed by confocal laser scanning microscope and flow cytometry using Annexin V/PI double staining. Moreover, protein expressions of Bcl-2 and Bax were detected by immunofluorescence. The results showed that few apoptotic cells were observed in normal control group, whereas the number of apoptotic cells was greatly increased in OGD group. Both normal and HPC CSF could decrease the apoptosis of cultured hippocampal neurons injured by OGD (P neurons by up-regulating expression of Bcl-2 and down-regulating expression of Bax.

  20. Selective transformation of syngas into gasoline-range hydrocarbons over mesoporous H-ZSM-5-supported cobalt nanoparticles.

    Science.gov (United States)

    Cheng, Kang; Zhang, Lei; Kang, Jincan; Peng, Xiaobo; Zhang, Qinghong; Wang, Ye

    2015-01-26

    Bifunctional Fischer-Tropsch (FT) catalysts that couple uniform-sized Co nanoparticles for CO hydrogenation and mesoporous zeolites for hydrocracking/isomerization reactions were found to be promising for the direct production of gasoline-range (C5-11 ) hydrocarbons from syngas. The Brønsted acidity results in hydrocracking/isomerization of the heavier hydrocarbons formed on Co nanoparticles, while the mesoporosity contributes to suppressing the formation of lighter (C1-4 ) hydrocarbons. The selectivity for C5-11 hydrocarbons could reach about 70 % with a ratio of isoparaffins to n-paraffins of approximately 2.3 over this catalyst, and the former is markedly higher than the maximum value (ca. 45 %) expected from the Anderson-Schulz-Flory distribution. By using n-hexadecane as a model compound, it was clarified that both the acidity and mesoporosity play key roles in controlling the hydrocracking reactions and thus contribute to the improved product selectivity in FT synthesis. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Evaluation, management and prevention of lower extremity youth ice hockey injuries

    Directory of Open Access Journals (Sweden)

    Popkin CA

    2016-11-01

    Full Text Available Charles A Popkin,1 Brian M Schulz,2 Caroline N Park,1 Thomas S Bottiglieri,1 T Sean Lynch1 1Department of Orthopedic Surgery, Center for Shoulder, Elbow and Sports Medicine at Columbia University, New York, NY, 2Kerlan‑Jobe Orthopedic Clinic, Los Angeles, CA, USA Abstract: Ice hockey is a fast-paced sport played by increasing numbers of children and adolescents in North America and around the world. Requiring a unique blend of skill, finesse, power and teamwork, ice hockey can become a lifelong recreational activity. Despite the rising popularity of the sport, there is ongoing concern about the high frequency of musculoskeletal injury associated with participation in ice hockey. Injury rates in ice hockey are among the highest in all competitive sports. Numerous research studies have been implemented to better understand the risks of injury. As a result, rule changes were adopted by the USA Hockey and Hockey Canada to raise the minimum age at which body checking is permitted to 13–14 years (Bantam level from 11–12 years (Pee Wee. Continuing the education of coaches, parents and players on rules of safe play, and emphasizing the standards for proper equipment use are other strategies being implemented to make the game safer to play. The objective of this article was to review the evaluation, management and prevention of common lower extremity youth hockey injuries. Keywords: youth hockey, body checking, injury prevention, femoroacetabular impingement, apophyseal avulsions

  2. Hydrogenation of carbon monoxide on WO/sub 3/-Supported ruthenium catalysts

    Energy Technology Data Exchange (ETDEWEB)

    Yoshinari, Tomohiro; Suganuma, Fujio; Sera, Chikara

    1988-01-01

    In this study, a WO/sub 3/-supported catalyst was prepared to conduct hydrogenation of CO for examining the product distribution and composition of hydrocarbons, using a gamma-alumina-supported catalyst for comparison. These catalysts were used under pressure to conduct a distributive reaction and the desorbing behavior of CO or H/sub 2/ at elevated temperature was measured to examine the influence of the type of carrier or the method of preparation on the activity and the distribution of products formed. The WO/sub 3/-supported catalyst gave a carbon chain length distribution that did not comply with the rule of Schulz-Flory, giving a composition richer in the isomers. Carbon number distribution is affected by Ru-dispersion, and the selectivity of isomers depends on the acidity of the carrier. Formed products distribution of the WO/sub 3/-supported reaction is attributable to the secondary reaction, which relates to the acidic point of the carrier, of the primary product formed on the metal. (7 figs, 4 tabs, 18 refs)

  3. Evaluation of one year of operation of the biogas plant in Suchohrdly u Miroslavi

    Directory of Open Access Journals (Sweden)

    Adam Moravec

    2011-01-01

    Full Text Available The manner of designing biogas plants is eagerly described by each and every seller or supplier of the respective technology. Numerous feasibility studies comprising forecasts of future operation featuring different quality levels have been written. However, it is rarely possible to obtain information comparing the anticipated future numbers and real values. Nevertheless, an evaluation of past operation of BGP is of utmost importance for calibration of the calculation methods used for designing of future BGPs. Information obtained on the basis of an evaluation is also useful for the purpose of verification of correct functionality of the equipment as well as optimisation of its operation with the objective of achieving the planned (or even better values of profitability of each respective project. A comprehensive analysis of a biogas plant is a project sensitive to accuracy of inputs. Measurements of amounts and quality of the feed substrate throughout the whole year, which comprises numerous criteria, is highly demanding and complicated, and therefore the objective of this evaluation is to analyze the performance, production and consumption of the biogas plant in the course of a calendar year (Schulz et al., 2004. Power measuring tasks are performed using calibrated gauges (which are mostly used for invoicing purposes, thus ensuring accuracy and credibility of the input data.

  4. Odonto-onycho-dermal dysplasia in a patient homozygous for a WNT10A nonsense mutation and mild manifestations of ectodermal dysplasia in carriers of the mutation.

    Science.gov (United States)

    Krøigård, Anne Bruun; Clemmensen, Ole; Gjørup, Hans; Hertz, Jens Michael; Bygum, Anette

    2016-03-10

    Odonto-onycho-dermal dysplasia (OODD) is a rare form of ectodermal dysplasia characterized by severe oligodontia, onychodysplasia, palmoplantar hyperkeratosis, dry skin, hypotrichosis, and hyperhidrosis of the palms and soles. The ectodermal dysplasias resulting from biallelic mutations in the WNT10A gene result in highly variable phenotypes, ranging from isolated tooth agenesis to OODD and Schöpf-Schulz-Passarge syndrome (SSPS). We identified a female patient, with consanguineous parents, who was clinically diagnosed with OODD. Genetic testing showed that she was homozygous for a previously reported pathogenic mutation in the WNT10A gene, c.321C > A, p.Cys107*. The skin and nail abnormalities were for many years interpreted as psoriasis and treated accordingly. A thorough clinical examination revealed hypotrichosis and hyperhidrosis of the soles and dental examination revealed agenesis of permanent teeth except the two maxillary central incisors. Skin biopsies from the hyperkeratotic palms and soles showed the characteristic changes of eccrine syringofibroadenomatosis, which has been described in patients with ectodermal dysplasias. Together with a family history of tooth anomalies, this lead to the clinical suspicion of a hereditary ectodermal dysplasia. This case illustrates the challenges of diagnosing ectodermal dysplasia like OODD and highlights the relevance of interdisciplinary cooperation in the diagnosis of rare conditions.

  5. Assessing two Theoretical Frameworks of Civic Engagement

    Directory of Open Access Journals (Sweden)

    Benilde García-Cabrero

    2016-03-01

    Full Text Available The purpose of this study was to empirically test two major theoretical models: a modified version of the social capital model (Pattie, Seyd and Whiteley, 2003, and the Informed Social Engagement Model (Barr and Selman, 2014; Selman and Kwok, 2010, to explain civic participation and civic knowledge of adolescents from Chile, Colombia and Mexico, using data from the International Civic and Citizenship Education Study 2009 (Schulz, et al., 2010. The models were used to identify factors associated with different levels of knowledge and civic participation: expected participation in legal and illegal protests, and electoral participation. Data were analyzed using regression analysis. Results show that the Informed Social Engagement approach (ISEM, explains better the observed differences in civic knowledge and civic participation, than the Social Capital Model (SCM. That is, the expected values associated with the variables included in the ISEM are closer to the observed values, than those predicted by the SCM. This is true for the three outcomes (expected participation in legal protests, illegal protests, and electoral participation and in the three countries analyzed (Chile, Colombia and Mexico.

  6. Parliamentarian sovereignty and technical development

    International Nuclear Information System (INIS)

    Dreier, H.; Hofmann, J.

    1986-01-01

    The title indicates the points of main emphasis of the contributions, and points to the programme embodied in the volume. The question is - given the tremendous and ever increasing amount of secondary problems associated with a heated technology development - whether the 'sovereign' state is at all capable of controlling, piloting and fostering technic-scientific processes. The first part ('sovereignty and parliamentarian legislator state') concentrates on the history of notions and ideas in the concept of the sovereign, modern state, and on the constitutional law in force (Dreier, Frohn); the current efficiency of parliament as an organ of control in the process of legislation is investigated (Schulze-Fielitz). The central concern of part 2 ('environmental law and technical development') are topical questions of environmental law (Hofmann, Luebbe-Wolff). Besides the analysis of dogmatic problems of a special administrative law, the major issue is whether and in how far - given modern large-scale technologies - law can adequately govern technique (Schmidt). By analyzing the relationship between technical development and possibilities for guidance by a parliamentarian constitutional state, the articles deal with a central point of intersection between state and administrative law. (orig./HP) [de

  7. Activity and selectivity regulation of synthesis gas reaction over supported ruthenium catalysts

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, K; Nobusawa, T; Fukushima, T; Tominaga, H

    1985-01-01

    The catalytic activities of supported ruthenium for synthesis-gas conversion to hydrocarbons was found to be in the following order: TiOS > Nb2O3 > ZrO2 > SiO2 > Ta2O5 > Al2O3 > V2O5 > MoO3 > WO3 > MnO2 > ZnO. Turnover frequencies of the supported ruthenium increased with decrease in dispersion of the metal particles for every carrier material. Even the activities per unit weight of metals were higher for low-dispersion ruthenium of Al2O3, TiO2, and ZrO2. The chain-growth probability of a hydrocarbon product, which is characterized by the Schulz-Flory distribution, increased markedly with decrease in the metal dispersion irrespective of the carrier material. The catalytic activity of ruthenium particles with a dispersed ruthenium increased almost linearly with an increase in reaction pressure (up to at least 2.0 MPa). 23 references, 10 figures, 3 tables.

  8. Outside-the-box, but Inside-the-elevator: A Case of Leadership Myopia Reaching Media

    Directory of Open Access Journals (Sweden)

    Miriam Costea

    2013-05-01

    Full Text Available Practitioners claim that successful leaders should be able to think out-of-the-box and “first break all the rules”. However, when it comes to organizational regulation inside some public institutions, more often than not the leaders replace the organizational creativity with an extreme exploitation of the existing rules. The “tendency to overinvest in exploitation” (Levinthal & March 1993 of the routines that proved successful in the past is well-known in the literature on organizational learning. In the present study, we examine a specific context in which a traditional rule meant to offer legitimacy to the public leaders was over-exploited up to the point when all national media reacted against the actions of the public institution. Thus, instead of obtaining more legitimacy, the leaders learned the hard way that the organizational rules should be assessed periodically and the obsolete ones be replaced/balanced with new rules, resulting from the exploratory dimension of organizational learning. We consider that an explanation for this specific case of leadership myopia may be found in a recently defined leadership style, ie, the spiritual leadership (Fry, 2003, situated in a case of over-exploiting an impermanent institutionalized rule (Schulz, 2003.

  9. Evaluations of the Spitzenkandidaten: The Role of Information and News Exposure in Citizens’ Preference Formation

    Directory of Open Access Journals (Sweden)

    Katjana Gattermann

    2016-02-01

    Full Text Available The 2014 European Parliament (EP elections were characterised by a novel element in European Union (EU politics. For the first time, the major European party families put forward top candidates for President of the European Commission, the so-called Spitzenkandidaten. This paper tests whether this innovation had the potential to—at least partially—alleviate the alleged accountability deficit. We rely on original survey data to assess citizens’ preferences for each of the main Spitzenkandidaten: Jean-Claude Juncker, Martin Schulz, and Guy Verhofstadt. Our research is guided by three questions: what explains whether citizens formulate a preference for a certain Spitzenkandidat? Which factors are responsible for variations in such preferences? And, are these explanations moderated by citizens’ political awareness? We show that three factors enable citizens to formulate a preference for the Spitzenkandidaten: news exposure, general EU political information, and campaign-specific information about the Spitzenkandidaten. Furthermore, we demonstrate that only the most knowledgeable citizens are able to use party cues in their evaluations of the Spitzenkandidaten. The implications of our findings are discussed with reference to the EU’s democratic deficit debate.

  10. CSNI Project for Fracture Analyses of Large-Scale International Reference Experiments (Project FALSIRE)

    International Nuclear Information System (INIS)

    Bass, B.R.; Pugh, C.E.; Keeney-Walker, J.; Schulz, H.; Sievers, J.

    1993-06-01

    This report summarizes the recently completed Phase I of the Project for Fracture Analysis of Large-Scale International Reference Experiments (Project FALSIRE). Project FALSIRE was created by the Fracture Assessment Group (FAG) of Principal Working Group No. 3 (PWG/3) of the Organization for Economic Cooperation and Development (OECD)/Nuclear Energy Agency's (NEA's) Committee on the Safety of Nuclear Installations (CSNI). Motivation for the project was derived from recognition by the CSNI-PWG/3 that inconsistencies were being revealed in predictive capabilities of a variety of fracture assessment methods, especially in ductile fracture applications. As a consequence, the CSNI/FAG was formed to evaluate fracture prediction capabilities currently used in safety assessments of nuclear components. Members are from laboratories and research organizations in Western Europe, Japan, and the United States of America (USA). On behalf of the CSNI/FAG, the US Nuclear Regulatory Commission's (NRC's) Heavy-Section Steel Technology (HSST) Program at the Oak Ridge National Laboratory (ORNL) and the Gesellschaft fuer Anlagen--und Reaktorsicherheit (GRS), Koeln, Federal Republic of Germany (FRG) had responsibility for organization arrangements related to Project FALSIRE. The group is chaired by H. Schulz from GRS, Koeln, FRG

  11. Villa San Michele at Capri – a House with a distinct home for "Genius Loci"

    DEFF Research Database (Denmark)

    Fisker, Anna Marie; Danielsen, Mads Harder

    2012-01-01

    on the spot. When we approached Capri by crossing the Neapolitan bay the first thing our eyes saw was the chapel of San Michele resting high above the blue waters at the top of the steep cliffs - on the edge of the abyss. This place is also the location of the Egyptian Sphinx, half lion, half woman...... that the spirit of the place adjoins a metaphysical core of architecture; and as the very core of architecture could be connected to an absolute truth so it seems that genius loci is related to truth; even though it is a truth that is not directly visible. We ask in this paper if it is a truth that is perennially...... are going to hear the Sphinx ask us questions, all these riddling puzzles, we first have to ask the Sphinx to know how to ask questions. That genius loci are present in architectural theory owes much to the Scandinavian theoretician and architect Christian Norberg-Schulz, who emphasized considerations...

  12. Superresolution upgrade for confocal spinning disk systems using image scanning microscopy (Conference Presentation)

    Science.gov (United States)

    Isbaner, Sebastian; Hähnel, Dirk; Gregor, Ingo; Enderlein, Jörg

    2017-02-01

    Confocal Spinning Disk Systems are widely used for 3D cell imaging because they offer the advantage of optical sectioning at high framerates and are easy to use. However, as in confocal microscopy, the imaging resolution is diffraction limited, which can be theoretically improved by a factor of 2 using the principle of Image Scanning Microscopy (ISM) [1]. ISM with a Confocal Spinning Disk setup (CSDISM) has been shown to improve contrast as well as lateral resolution (FWHM) from 201 +/- 20 nm to 130 +/- 10 nm at 488 nm excitation. A minimum total acquisition time of one second per ISM image makes this method highly suitable for 3D live cell imaging [2]. Here, we present a multicolor implementation of CSDISM for the popular Micro-Manager Open Source Microscopy platform. Since changes in the optical path are not necessary, this will allow any researcher to easily upgrade their standard Confocal Spinning Disk system at remarkable low cost ( 5000 USD) with an ISM superresolution option. [1]. Müller, C.B. and Enderlein, J. Image Scanning Microscopy. Physical Review Letters 104, (2010). [2]. Schulz, O. et al. Resolution doubling in fluorescence microscopy with confocal spinning-disk image scanning microscopy. Proceedings of the National Academy of Sciences of the United States of America 110, 21000-5 (2013).

  13. Electron induced break-up of helium. Benchmark experiments on a dynamical four-body Coulomb system

    Energy Technology Data Exchange (ETDEWEB)

    Duerr, M.

    2006-07-05

    This work presents an experimental study of fragmentation of helium by electron impact, in which absolute fully differential cross sections for single ionization, ionization-excitation and double ionization were determined. By applying a charged-particle imaging technique, the so-called 'reaction microscope', a large fraction of the final-state momentum space is covered, and the major limitations of previous experimental methods applied in this field could be overcome. Decisive modifications of the previous reaction microscope were undertaken, the most important one being the arrangement of the projectile beam parallel to the imaging-fields. For single ionization on helium an enhanced electron emission outside the projectile scattering plane is observed at both considered impact energies (102 eV and 1 keV), which is similar to the result found for ion-impact (M. Schulz et al., Nature (London) 422, 48 (2003)). The angle resolved cross sections obtained for double ionization at 105 eV impact energy reveal, that the process is dominated by the mutual repulsion of the three final-state continuum electrons. However, signatures of more complex dynamics are also observed. The data provide an ultimate benchmark for recently developed theories treating the dynamical three- and four-body Coulomb problem. (orig.)

  14. Electron induced break-up of helium. Benchmark experiments on a dynamical four-body Coulomb system

    International Nuclear Information System (INIS)

    Duerr, M.

    2006-01-01

    This work presents an experimental study of fragmentation of helium by electron impact, in which absolute fully differential cross sections for single ionization, ionization-excitation and double ionization were determined. By applying a charged-particle imaging technique, the so-called 'reaction microscope', a large fraction of the final-state momentum space is covered, and the major limitations of previous experimental methods applied in this field could be overcome. Decisive modifications of the previous reaction microscope were undertaken, the most important one being the arrangement of the projectile beam parallel to the imaging-fields. For single ionization on helium an enhanced electron emission outside the projectile scattering plane is observed at both considered impact energies (102 eV and 1 keV), which is similar to the result found for ion-impact (M. Schulz et al., Nature (London) 422, 48 (2003)). The angle resolved cross sections obtained for double ionization at 105 eV impact energy reveal, that the process is dominated by the mutual repulsion of the three final-state continuum electrons. However, signatures of more complex dynamics are also observed. The data provide an ultimate benchmark for recently developed theories treating the dynamical three- and four-body Coulomb problem. (orig.)

  15. Influence of Telecommunication Modality, Internet Transmission Quality, and Accessories on Speech Perception in Cochlear Implant Users

    Science.gov (United States)

    Koller, Roger; Guignard, Jérémie; Caversaccio, Marco; Kompis, Martin; Senn, Pascal

    2017-01-01

    Background Telecommunication is limited or even impossible for more than one-thirds of all cochlear implant (CI) users. Objective We sought therefore to study the impact of voice quality on speech perception with voice over Internet protocol (VoIP) under real and adverse network conditions. Methods Telephone speech perception was assessed in 19 CI users (15-69 years, average 42 years), using the German HSM (Hochmair-Schulz-Moser) sentence test comparing Skype and conventional telephone (public switched telephone networks, PSTN) transmission using a personal computer (PC) and a digital enhanced cordless telecommunications (DECT) telephone dual device. Five different Internet transmission quality modes and four accessories (PC speakers, headphones, 3.5 mm jack audio cable, and induction loop) were compared. As a secondary outcome, the subjective perceived voice quality was assessed using the mean opinion score (MOS). Results Speech telephone perception was significantly better (median 91.6%, P 15%) were not superior to conventional telephony. In addition, there were no significant differences between the tested accessories (P>.05) using a PC. Coupling a Skype DECT phone device with an audio cable to the CI, however, resulted in higher speech perception (median 65%) and subjective MOS scores (3.2) than using PSTN (median 7.5%, P<.001). Conclusions Skype calls significantly improve speech perception for CI users compared with conventional telephony under real network conditions. Listening accessories do not further improve listening experience. Current Skype DECT telephone devices do not fully offer technical advantages in voice quality. PMID:28438727

  16. Elevating the quality of disability and rehabilitation research: mandatory use of the reporting guidelines.

    Science.gov (United States)

    Chan, Leighton; Heinemann, Allen W; Roberts, Jason

    2014-01-01

    Note from the AJOT Editor-in-Chief: Since 2010, the American Journal of Occupational Therapy (AJOT) has adopted reporting standards based on the Consolidated Standards of Reporting Trials (CONSORT) Statement and American Psychological Association (APA) guidelines in an effort to publish transparent clinical research that can be easily evaluated for methodological and analytical rigor (APA Publications and Communications Board Working Group on Journal Article Reporting Standards, 2008; Moher, Schulz, & Altman, 2001). AJOT has now joined 28 other major rehabilitation and disability journals in a collaborative initiative to enhance clinical research reporting standards through adoption of the EQUATOR Network reporting guidelines, described below. Authors will now be required to use these guidelines in the preparation of manuscripts that will be submitted to AJOT. Reviewers will also use these guidelines to evaluate the quality and rigor of all AJOT submissions. By adopting these standards we hope to further enhance the quality and clinical applicability of articles to our readers. Copyright © 2014 by the American Occupational Therapy Association, Inc.

  17. Genetic diversity of Ixodes ricinus (Ixodida: Ixodidae) ticks in sympatric and allopatric zones in Baltic countries.

    Science.gov (United States)

    Paulauskas, A; Galdikaitė-Brazienė, E; Radzijevskaja, J; Aleksandravičienė, A; Galdikas, M

    2016-12-01

    Ixodes ricinus (Linnaeus 1758) and Ixodes persulcatus (Schulze 1930) ticks are involved in the transmission of a wide variety of pathogens with considerable impact on human and animal health. The co-distribution zone of these two tick species is situated in the Baltic countries, which provides a special setting for the population studies. In the present study, genetic variability of I. ricinus ticks collected in allopatric and sympatric locations in the Baltic countries has been investigated using a sequence analysis of the mitochondrial DNA control region, 16S rRNA and cytb genes. There were 32 haplotypes (Hd: 0.8551) and 27 haplotypes (Hd:0.8213) of control region sequences from ticks in allopatric and sympatric zones detected, respectively. Out of 47 16S rRNA gene haplotypes, 32 haplotypes (Hd: 0.7213) were found in the allopatric zone and 27 (Hd:0.9572) in the sympatric zone. The Cytb gene was very conserved and monomorphic in ticks from the allopatric zone, whereas three unique haplotypes were observed in the sympatric zone. The higher number of unique haplotypes of the control region was detected in the allopatric zone. Median joining network and Fst analysis did not reveal a clear separation between ticks from the two zones. © 2016 The Society for Vector Ecology.

  18. Yield, Esterification Degree and Molecular Weight Evaluation of Pectins Isolated from Orange and Grapefruit Peels under Different Conditions

    Science.gov (United States)

    Sayah, Mohamed Yassine; Chabir, Rachida; Benyahia, Hamid; Rodi Kandri, Youssef; Ouazzani Chahdi, Fouad; Touzani, Hanan; Errachidi, Faouzi

    2016-01-01

    Orange (Citrus sinensis) and grapefruit (Citrus paradise) peels were used as a source of pectin, which was extracted under different conditions. The peels are used under two states: fresh and residual (after essential oil extraction). Organic acid (citric acid) and mineral acid (sulfuric acid) were used in the pectin extraction. The aim of this study is the evaluation the effect of extraction conditions on pectin yield, degree of esterification “DE” and on molecular weight “Mw”. Results showed that the pectin yield was higher using the residual peels. Moreover, both peels allow the obtainment of a high methoxyl pectin with DE >50%. The molecular weight was calculated using Mark-Houwink-Sakurada equation which describes its relationship with intrinsic viscosity. This later was determined using four equations; Huggins equation, kramer, Schulz-Blaschke and Martin equation. The molecular weight varied from 1.538 x1005 to 2.47x1005 g/mol for grapefruit pectin and from 1.639 x1005 to 2.471 x1005 g/mol for orange pectin. PMID:27644093

  19. The international trade in reptiles (Reptilia)--the cause of the transfer of exotic ticks (Acari: Ixodida) to Poland.

    Science.gov (United States)

    Nowak, Magdalena

    2010-05-11

    The problem of the unnatural transfer of exotic ticks (Acari: Ixodida) on reptiles (Reptilia) imported to Poland is presented. In the period from 2003 to 2007, 382 specimens of reptiles belonging to the following genera were investigated: Testudo, Iguana, Varanus, Gongylophis, Python, Spalerosophis, Psammophis. The reptiles most infested with ticks are imported to Poland from Ghana in Africa, and are the commonly bred terrarium reptiles: Varanus exanthematicus and Python regius. As a result of the investigations, the transfer of exotic ticks on reptiles to Poland was confirmed. There were 2104 specimens of the genera Amblyomma and Hyalomma. The following species were found: Amblyomma exornatum Koch, 1844, Amblyomma flavomaculatum (Lucas, 1846), Amblyomma latum Koch, 1844, Amblyomma nuttalli Donitz, 1909, Amblyomma quadricavum (Schulze, 1941), Amblyomma transversale (Lucas, 1844), Amblyomma varanense (Supino, 1897), Amblyomma sp. Koch, 1844, Hyalomma aegyptium (Linnaeus, 1758). All the species of ticks of genus Amblyomma revealed have been discovered in Poland for the first time. During the research, 13 cases of anomalies of morphological structure were confirmed in the ticks A. flavomaculatum, A. latum and H. aegyptium. The expanding phenomenon of the import of exotic reptiles in Poland and Central Europe is important for parasitological and epidemiological considerations, and therefore requires monitoring and wide-ranging prophylactic activities to prevent the inflow of exotic parasites to Poland. (c) 2010 Elsevier B.V. All rights reserved.

  20. Giant basal spicule from the deep-sea glass sponge Monorhaphis chuni: synthesis of the largest bio-silica structure on Earth by silicatein

    Science.gov (United States)

    Wang, Xiao-hong; Zhang, Xue-hua; Schröder, Heinz C.; Müller, Werner E. G.

    2009-09-01

    Like all sponges (phylum Porifera), the glass sponges (Hexactinellida) are provided with an elaborate and distinct body plan, which relies on a filigree skeleton. It is constructed by an array of morphologically determined elements, the spicules. Schulze described the largest siliceous hexactinellid sponge on Earth, the up to 3 m high Monorhaphis chuni, collected during the German Deep Sea Expedition "Valdivia" (1898-1899). This species develops an equally large bio-silica structure, the giant basal spicule (3 m × 10 mm). Using these spicules as a model, one can obtain the basic knowledge on the morphology, formation, and development of silica skeletal elements. The silica matrix is composed of almost pure silica, endowing it with unusual optophysical properties, which are superior to those of man-made waveguides. Experiments suggest that the spicules function in vivo as a nonocular photoreception system. The spicules are also provided with exceptional mechanical properties. Like demosponges, the hexactinellids synthesize their silica enzymatically via the enzyme silicatein (27 kDa protein). This enzyme is located in/embedded in the silica layers. This knowledge will surely contribute to a further utilization and exploration of silica in biomaterial/biomedical science.

  1. Rheological Modeling and Characterization of Ficus platyphylla Gum Exudates

    Directory of Open Access Journals (Sweden)

    Nnabuk O. Eddy

    2013-01-01

    Full Text Available Ficus platyphylla gum exudates (FP gum have been analyzed for their physicochemical parameters and found to be ionic, mildly acidic, odourless, and yellowish brown in colour. The gum is soluble in water, sparingly soluble in ethanol, and insoluble in acetone and chloroform. The nitrogen (0.39% and protein (2.44% contents of the gum are relatively low. The concentrations of the cations were found to increase according to the following trend, Mn>Fe>Zn>Pb>Cu>Mg>Cd>Ca. Analysis of the FTIR spectrum of the gum revealed vibrations similar to those found in polysaccharides while the scanning electron micrograph indicated that the gum has irregular molecular shapes, arranged randomly. The intrinsic viscosity of FP gum estimated by extrapolating to zero concentrations in Huggins, Kraemer, Schulz-Blaschke, and Martin plots has an average value of 7 dL/g. From the plots of viscosity versus shear rate/speed of rotation and also that of shear stress versus shear rate, FP gum can be classified as a non-Newtonian gum with characteristics-plastic properties. Development of the Master_s curve for FP gum also indicated that the gum prefers to remain in a dilute domain (C

  2. Identifying the Structure and Effect of Drinking-Related Self-Schemas.

    Science.gov (United States)

    Domenico, Lisa H; Strobbe, Stephen; Stein, Karen Farchaus; Giordani, Bruno J; Hagerty, Bonnie M; Pressler, Susan J

    2017-07-01

    Self-schemas have received increased attention as favorable targets for therapeutic intervention because of their central role in self-perception and behavior. The purpose of this integrative review was to identify, evaluate, and synthesize existing research pertaining to drinking-related self-schemas. Russell's integrative review strategy guided the search. Sixteen published works were identified, meeting criteria for evaluation ( n = 12 data-based publications and n = 4 models). The retrieved data-based publications rated fair-good using Polit and Beck's criteria; the overall body of literature rated "B" using Grimes and Schulz criteria. Retrieved models rated 4 to 7 using Fitzpatrick and Whall's criteria. The existing literature strongly supports the availability of a drinking-related self-schema among moderate-to-heavy drinking samples, and suggests a positive relationship between elaboration and drinking behavior. The relationship between valenced content of the schema and drinking behavior remains unexplored. Identifying variation in the structural properties of drinking-related self-schemas could lay the foundation for future interventions.

  3. Neue Medien unter der Organisationsperspektive. Eine empirische Untersuchung in der Weiterbildung

    Directory of Open Access Journals (Sweden)

    Richard Stang

    2017-08-01

    Full Text Available Gesellschaftliche Modernisierungsprozesse haben zu immensen Veränderungsprozessen auf allen Ebenen gesellschaftlichen Lebens geführt. Wirtschaft, Politik, Bildungswesen etc. sind als Gesamtsysteme davon betroffen, genauso wie die Institutionen und Organisationen, die in deren Rahmen agieren. Stehr (2000, S. 17 spricht davon, dass wir uns in einem „Übergangsstadium zwischen zwei Gesellschaftsformationen“ befinden und meint damit den Übergang von der „Industriegesellschaft“ zur „Wissensgesellschaft“, in der Wissen konstitutiv für die Gesellschaftsformation ist. Mit dem Bedeutungszuwachs der Ressource „Wissen“ gehen Prozesse der voranschreitenden gesellschaftlichen Ausdifferenzierung einher. So unterschiedlich die sozialwissenschaftlichen Analysen der Gesellschaftsformation und die daraus gefolgerten theoretischen Konstrukte auch sein mögen (vgl. u.a. Beck 1986, Castells 2001, Gross 1994, Schulze 1993, wird doch in einem besonderen Maße die Entwicklung von Technik, besonders der Informations- und Kommunikationstechniken (im Folgenden: Neuen Medien, als ein wichtiger Motor der gesellschaftlichen Veränderungsprozesse gesehen. Besonders Castells (2001 hat die gesellschaftliche, kulturelle und ökonomische Bedeutung der Neuen Medien in seiner Studie über die Netzwerkgesellschaft eindrucksvoll herausgearbeitet.

  4. Internet video telephony allows speech reading by deaf individuals and improves speech perception by cochlear implant users.

    Directory of Open Access Journals (Sweden)

    Georgios Mantokoudis

    Full Text Available OBJECTIVE: To analyze speech reading through Internet video calls by profoundly hearing-impaired individuals and cochlear implant (CI users. METHODS: Speech reading skills of 14 deaf adults and 21 CI users were assessed using the Hochmair Schulz Moser (HSM sentence test. We presented video simulations using different video resolutions (1280 × 720, 640 × 480, 320 × 240, 160 × 120 px, frame rates (30, 20, 10, 7, 5 frames per second (fps, speech velocities (three different speakers, webcameras (Logitech Pro9000, C600 and C500 and image/sound delays (0-500 ms. All video simulations were presented with and without sound and in two screen sizes. Additionally, scores for live Skype™ video connection and live face-to-face communication were assessed. RESULTS: Higher frame rate (>7 fps, higher camera resolution (>640 × 480 px and shorter picture/sound delay (<100 ms were associated with increased speech perception scores. Scores were strongly dependent on the speaker but were not influenced by physical properties of the camera optics or the full screen mode. There is a significant median gain of +8.5%pts (p = 0.009 in speech perception for all 21 CI-users if visual cues are additionally shown. CI users with poor open set speech perception scores (n = 11 showed the greatest benefit under combined audio-visual presentation (median speech perception +11.8%pts, p = 0.032. CONCLUSION: Webcameras have the potential to improve telecommunication of hearing-impaired individuals.

  5. Individualism and socioeconomic diversity at school as related to perceptions of the frequency of peer aggression in fifteen countries.

    Science.gov (United States)

    Menzer, Melissa M; Torney-Purta, Judith

    2012-10-01

    The purpose of this study was to examine two aspects of context for peer aggression: national individualism and distributions of socioeconomic status in the school. School administrators for each school reported on their perceptions of the frequency of bullying and violence in their school. The sample comprised 990 school principals/headmasters from nationally representative samples of schools in 15 countries surveyed as part of the larger IEA Civic Education Study (Torney-Purta, Lehmann, Oswald, & Schulz, 2001). A national context of individualism was associated with violence but not bullying. Schools with high socioeconomic diversity had more bullying than homogeneously low or high socioeconomic status schools. In addition, diverse schools had more violence than affluent schools. Results suggest that bullying and violence should be investigated as separate constructs. Furthermore, contexts, such as national culture and school socioeconomic diversity, are important in understanding the prevalence of bullying and violence in schools internationally. Copyright © 2012 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  6. Electron Radiation Belts of the Solar System

    Science.gov (United States)

    Mauk, Barry; Fox, Nicola

    To address the question of what factors dictate similarities and differences between radiation belts, we present comparisons between the electron radiation belt spectra of all five strongly magnetized planets within the solar system: Earth, Jupiter, Saturn, Uranus, and Neptune. We choose the highest intensity observed electron spectrum within each system (highest specifically near 1 MeV) and compare them against expectations based on the so-called Kennel-Petschek limit (KP; 1966) for each system. For evaluating the KP limit, we begin with the new relativis-tically correct formulation of Summers et al. (2009) but then add several refinements of our own. Specifically, we: 1) utilized a much more flexible analytic spectral shape that allows us to accurately fit observed radiation belt spectra; 2) adopt the point of view that the anisotropy parameter is not a free parameter but must take on a minimal value, as originally proposed by Kennel and Petschek (1966); and 3) examine the differential characteristics of the KP limit along the lines of what Schulz and Davidson (1988) performed for the non-relativistic formula-tion. We find that three factors limit the highest electron radiation belt intensities within solar system planetary magnetospheres: a) whistler mode interactions that limit spectral intensities to a differential Kennel-Petschek limit (3 planets); b) the absence of robust acceleration pro-cesses associated with injection dynamics (1 planet); and c) material interactions between the radiation particles and clouds of gas and dust (1 planet).

  7. Conceptual processing in music as revealed by N400 effects on words and musical targets.

    Science.gov (United States)

    Daltrozzo, Jérôme; Schön, Daniele

    2009-10-01

    The cognitive processing of concepts, that is, abstract general ideas, has been mostly studied with language. However, other domains, such as music, can also convey concepts. Koelsch et al. [Koelsch, S., Kasper, E., Sammler, D., Schulze, K., Gunter, T., & Friederici, A. D. Music, language and meaning: Brain signatures of semantic processing. Nature Neuroscience, 7, 302-307, 2004] showed that 10 sec of music can influence the semantic processing of words. However, the length of the musical excerpts did not allow the authors to study the effect of words on musical targets. In this study, we decided to replicate Koelsch et al. findings using 1-sec musical excerpts (Experiment 1). This allowed us to study the reverse influence, namely, of a linguistic context on conceptual processing of musical excerpts (Experiment 2). In both experiments, we recorded behavioral and electrophysiological responses while participants were presented 50 related and 50 unrelated pairs (context/target). Experiments 1 and 2 showed a larger N400 component of the event-related brain potentials to targets following a conceptually unrelated compared to a related context. The presence of an N400 effect with musical targets suggests that music may convey concepts. The relevance of these results for the comprehension of music as a structured set of conceptual units and for the domain specificity of the mechanisms underlying N400 effects are discussed.

  8. School Engagement and Civic Engagement as Predictors for the Future Political Participation of Ethnic Chinese and South Asian Adolescents in Hong Kong

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    Celeste Y. M. Yuen

    2013-12-01

    Full Text Available This paper reports the findings of a large study on the relationship between school and civic engagement and the self-perceived participation in political activities of ethnic Chinese and South Asian immigrant students in Hong Kong. Data was col¬lected from a sample of 5,574 6th – 11th graders aged 12−19. The nature of school engagement was assessed by a self-rated questionnaire against the affective, behavioral and cognitive domains. Students’ civic engagement was measured by the ICCS student questionnaire (Schulz et al., 2009. Before running the regression analyses, Confirmatory Factor Analysis (CFA was performed and the results showed that both instruments had good construct validity and internal consistency. Consistent with the primary aim of this study, MANOVA analyses indicate significant student group differences in school engagement, and civic related self-belief and behaviours. Our findings showed that non-Chinese speaking South Asian students (NCS scored higher than their mainstream Chinese and newly arrived students from Mainland China (NAS counterparts across the dimensions of both instruments. Results of hierarchical regressions confirmed that school engagement was significant in pre¬dicting expected political participation in the future. The effects of school and civic engagement on future political participation varied significantly between all studied groups.

  9. Power to Fuels: Dynamic Modeling of a Slurry Bubble Column Reactor in Lab-Scale for Fischer Tropsch Synthesis under Variable Load of Synthesis Gas

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    Siavash Seyednejadian

    2018-03-01

    Full Text Available This research developed a comprehensive computer model for a lab-scale Slurry Bubble Column Reactor (SBCR (0.1 m Dt and 2.5 m height for Fischer–Tropsch (FT synthesis under flexible operation of synthesis gas load flow rates. The variable loads of synthesis gas are set at 3.5, 5, 7.5 m3/h based on laboratory adjustments at three different operating temperatures (483, 493 and 503 K. A set of Partial Differential Equations (PDEs in the form of mass transfer and chemical reaction are successfully coupled to predict the behavior of all the FT components in two phases (gas and liquid over the reactor bed. In the gas phase, a single-bubble-class-diameter (SBCD is adopted and the reduction of superficial gas velocity through the reactor length is incorporated into the model by the overall mass balance. Anderson Schulz Flory distribution is employed for reaction kinetics. The modeling results are in good agreement with experimental data. The results of dynamic modeling show that the steady state condition is attained within 10 min from start-up. Furthermore, they show that step-wise syngas flow rate does not have a detrimental influence on FT product selectivity and the dynamic modeling of the slurry reactor responds quite well to the load change conditions.

  10. Calculation of skid resistance from texture measurements

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    Andreas Ueckermann

    2015-02-01

    Full Text Available There is a wide range of routine skid resistance measurement devices on the market. All of them are measuring the friction force between a rubber wheel and the wetted road surface. Common to all of them is that they are relatively complex and costly because generally a truck carrying a large water tank is needed to wet the surface with a defined water layer. Because of the limited amount of water they can carry they are limited in range. Besides that the measurement is depending on factors like water film thickness, temperature, measurement speed, rubber aging, rubber wear and even road evenness and curviness. All of these factors will affect the skid resistance and are difficult to control. We present a concept of contactless skid resistance measurement which is based on optical texture measurement and consists of two components: measurement of the pavement texture by means of an optical measuring system and calculation of the skid resistance based on the measured texture by means of a rubber friction model. The basic assumptions underlying the theoretical approach and the model itself based on the theory of Persson are presented. The concept is applied to a laboratory device called Wehner/Schulze (W/S machine to prove the theoretical approach. The results are very promising. A strong indication could be provided that skid resistance could be measured without contact in the future.

  11. Transcultural Writers and Transcultural Literature in the Age of Global Modernity

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    Arianna Dagnino

    2012-05-01

    Full Text Available Peer reviewed article. In our rapidly globalising world, cultures, as well as societies and identities, tend to be more fluid, less irreducibly different and less 'territorially fixed' than in the past (Schulze-Engler 2007, p. 27. Especially now, when cosmopolitan issues and pluralistic sensibilities - driven by transnational and transcommunal experiences - tend to become more relevant. It is within this emerging social context that a new generation of mobile writers, on the move across cultural and national boundaries, has started expressing a "transcultural" sensibility and mode of being, fostered by "the process of self-distancing, self-estrangement, and self criticism of one's own cultural identities and assumptions" (Epstein 1999, p. 307. In this paper, I argue that the main element that distinguishes these early 'transcultural writers' from their precursors and/or 'cousin species' (migrant/exile/diasporic/postcolonial writers - albeit all belonging to the wider 'genus' of 'the literature of mobility' - is their relaxed, neonomadic attitude when facing issues linked to identity, nationality, rootlessness and dislocation. An attitude that reflects itself also in their creative outputs, which can already be inscribed within the realm of transcultural literature, a literature able to transcend the borders of a single culture in its choice of topic, vision and scope, thus contributing to promote a wider global literary perspective (Pettersson 2006.

  12. Unusual foreign body in the sigmoid colon, chronic alcohol abuse, and Fournier gangrene: a case report

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    Schulz D

    2015-03-01

    Full Text Available Dietmar Schulz,1 Georgiana Simona Mohor,2 Caius Solovan2,3 1Sana Kliniken Leipziger Land, Klinik fur Urologie, Borna, Leipzig, Germany; 2University Clinic of Dermatology and Venereology, Timisoara, Romania; 3Department of Dermatology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania Abstract: Fournier gangrene (FG is an infectious condition with fulminant evolution and is sometimes life-threatening. Here, we present the case of an immunocompromised 59-year-old male with surgical history of a pancreatic pseudocyst stented endoscopically. After unrecognized stent migration in the sigmoid without colonic perforation, he developed severe necrosis of the scrotum and perineum, which spontaneously perforated, presenting a smell suggesting moist gangrene. FG that has spread to the male genital organs presents therapeutic challenges. The purpose of our study is to present this case, typical for FG, with an educational aim both for the internal and surgical specialties, and the goal of further multidisciplinary collaboration for the optimal management of the patient with personalized treatment. Keywords: pancreatic stent, wound debridement, vacuum-assisted closure, transplanted skin, necrotizing infection

  13. Effect of technological advances on cochlear implant performance in adults.

    Science.gov (United States)

    Lenarz, Minoo; Joseph, Gert; Sönmez, Hasibe; Büchner, Andreas; Lenarz, Thomas

    2011-12-01

    To evaluate the effect of technological advances in the past 20 years on the hearing performance of a large cohort of adult cochlear implant (CI) patients. Individual, retrospective, cohort study. According to technological developments in electrode design and speech-processing strategies, we defined five virtual intervals on the time scale between 1984 and 2008. A cohort of 1,005 postlingually deafened adults was selected for this study, and their hearing performance with a CI was evaluated retrospectively according to these five technological intervals. The test battery was composed of four standard German speech tests: Freiburger monosyllabic test, speech tracking test, Hochmair-Schulz-Moser (HSM) sentence test in quiet, and HSM sentence test in 10 dB noise. The direct comparison of the speech perception in postlingually deafened adults, who were implanted during different technological periods, reveals an obvious improvement in the speech perception in patients who benefited from the recent electrode designs and speech-processing strategies. The major influence of technological advances on CI performance seems to be on speech perception in noise. Better speech perception in noisy surroundings is strong proof for demonstrating the success rate of new electrode designs and speech-processing strategies. Standard (internationally comparable) speech tests in noise should become an obligatory part of the postoperative test battery for adult CI patients. Copyright © 2011 The American Laryngological, Rhinological, and Otological Society, Inc.

  14. Edades relativas de cúmulos globulares

    Science.gov (United States)

    Miller Bertolami, M.; Forte, J. C.

    El trabajo de Rossemberg et al (1999), estudia las edades relativas de cúmulos globulares galácticos mediante el análisis de ciertos parámetros morfológicos de los diagramas color-magnitud de dichos cúmulos. Este trabajo se centra en tres puntos: analizar la consistencia de los resultados obtenidos por Rossemberg et al (1999) al emplear observaciones en el sistema fotométrico de Washington, más precisamente, las magnitudes C y T1 en lugar de las magnitudes V e I utilizadas por dichos autores. De la existencia de colores integrados, metalicidad y edad (relativa) para 21 de los cúmulos utilizados en dicho trabajo, se analiza la consistencia de estos resultados con las dependencias de color integrado como función de la edad y la metalicidad que se desprenden de los modelos teóricos de luz integrada por Worthey (1994), Schulz (2002) y Lee et al (2002). Por último se lleva a cabo una breve comparación de la morfología de los diagramas color-magnitud de los cúmulos globulares y de las isocronas utilizadas, a fin de intentar identificar algunas de las posibles causas de las diferencias observadas en los incisos anteriores.

  15. Innovations in nanotechnology for water treatment

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    Gehrke I

    2015-01-01

    Full Text Available Ilka Gehrke, Andreas Geiser, Annette Somborn-SchulzFraunhofer Institute for Environmental, Safety and Energy Technology UMSICHT, Oberhausen, GermanyAbstract: Important challenges in the global water situation, mainly resulting from worldwide population growth and climate change, require novel innovative water technologies in order to ensure a supply of drinking water and reduce global water pollution. Against this background, the adaptation of highly advanced nanotechnology to traditional process engineering offers new opportunities in technological developments for advanced water and wastewater technology processes. Here, an overview of recent advances in nanotechnologies for water and wastewater treatment processes is provided, including nanobased materials, such as nanoadsorbents, nanometals, nanomembranes, and photocatalysts. The beneficial properties of these materials as well as technical barriers when compared with conventional processes are reported. The state of commercialization is presented and an outlook on further research opportunities is given for each type of nanobased material and process. In addition to the promising technological enhancements, the limitations of nanotechnology for water applications, such as laws and regulations as well as potential health risks, are summarized. The legal framework according to nanoengineered materials and processes that are used for water and wastewater treatment is considered for European countries and for the USA.Keywords: nanotechnology, water technology, nanoadsorbents, nanometals, nanomembranes, photocatalysis

  16. CSNI Project for Fracture Analyses of Large-Scale International Reference Experiments (Project FALSIRE)

    Energy Technology Data Exchange (ETDEWEB)

    Bass, B.R.; Pugh, C.E.; Keeney-Walker, J. [Oak Ridge National Lab., TN (United States); Schulz, H.; Sievers, J. [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) mbH, Koeln (Gemany)

    1993-06-01

    This report summarizes the recently completed Phase I of the Project for Fracture Analysis of Large-Scale International Reference Experiments (Project FALSIRE). Project FALSIRE was created by the Fracture Assessment Group (FAG) of Principal Working Group No. 3 (PWG/3) of the Organization for Economic Cooperation and Development (OECD)/Nuclear Energy Agency`s (NEA`s) Committee on the Safety of Nuclear Installations (CSNI). Motivation for the project was derived from recognition by the CSNI-PWG/3 that inconsistencies were being revealed in predictive capabilities of a variety of fracture assessment methods, especially in ductile fracture applications. As a consequence, the CSNI/FAG was formed to evaluate fracture prediction capabilities currently used in safety assessments of nuclear components. Members are from laboratories and research organizations in Western Europe, Japan, and the United States of America (USA). On behalf of the CSNI/FAG, the US Nuclear Regulatory Commission`s (NRC`s) Heavy-Section Steel Technology (HSST) Program at the Oak Ridge National Laboratory (ORNL) and the Gesellschaft fuer Anlagen--und Reaktorsicherheit (GRS), Koeln, Federal Republic of Germany (FRG) had responsibility for organization arrangements related to Project FALSIRE. The group is chaired by H. Schulz from GRS, Koeln, FRG.

  17. Chandra Discovers the X-ray Signature of a Powerful Wind from a Galactic Microquasar

    Science.gov (United States)

    2000-11-01

    NASA's Chandra X-ray Observatory has detected, for the first time in X rays, a stellar fingerprint known as a P Cygni profile--the distinctive spectral signature of a powerful wind produced by an object in space. The discovery reveals a 4.5-million-mile-per-hour wind coming from a highly compact pair of stars in our galaxy, report researchers from Penn State and the Massachusetts Institute of Technology in a paper they will present on 8 November 2000 during a meeting of the High-Energy Astrophysics Division of the American Astronomical Society in Honolulu, Hawaii. The paper also has been accepted for publication in The Astrophysical Journal Letters. "To our knowledge, these are the first P Cygni profiles reported in X rays," say researchers Niel Brandt, assistant professor of astronomy and astrophysics at Penn State, and Norbert S. Schulz, research scientist at the Massachusetts Institute of Technology. The team made the discovery during their first observation of a binary-star system with the Chandra X-ray Observatory, which was launched into space in July 1999. The system, known as Circinus X-1, is located about 20,000 light years from Earth in the constellation Circinus near the Southern Cross. It contains a super-dense neutron star in orbit around a normal fusion-burning star like our Sun. Although Circinus X-1 was discovered in 1971, many properties of this system remain mysterious because Circinus X-1 lies in the galactic plane where obscuring dust and gas have blocked its effective study in many wavelengths. The P Cygni spectral profile, previously detected primarily at ultraviolet and optical wavelengths but never before in X rays, is the textbook tool astronomers rely on for probing stellar winds. The profile looks like the outline of a roller coaster, with one really big hill and valley in the middle, on a data plot with velocity on one axis and the flow rate of photons per second on the other. It is named after the famous star P Cygni, in which such

  18. Nuclear Fusion Award 2010 speech Nuclear Fusion Award 2010 speech

    Science.gov (United States)

    Rice, John

    2011-01-01

    Following the suggestion of Earl Marmar in 1995, I installed a compact von Hamos type x-ray spectrometer (originally built with Elisabeth Rachlew and Jan Kallne) on a tangentially viewing port on the Alcator C-Mod tokamak. The spectrometer views the plasma through a 2 cm diameter hole, and is tuned to H-like argon, suitable for passive measurement of the core toroidal rotation velocity from the Doppler shift. It soon became evident that the rotation in Ohmic L-mode discharges, while for the most part directed counter-current, depends in a very complicated fashion on plasma parameters, notably the electron density, current and magnetic configuration. The rotation can even flip sign for almost no apparent reason! In Ohmic and ion cyclotron range of frequencies (ICRF) heated H-mode plasmas the rotation is in the co-current direction and has a relatively simple dependence on plasma parameters, proportional to the stored energy normalized to the current. Rotation velocities as high as 130 km s-1 have been observed without external momentum input. In dimensionless terms this intrinsic (or spontaneous rotation) depends on the normalized plasma pressure. The association of toroidal rotation with plasma pressure in ICRF H-modes was first observed by Lars-Goran Eriksson in JET discharges. Similar results were subsequently reported for Tore Supra enhanced confinement plasmas. In the early 2000s concerns began to surface about the lack of substantial neutral beam driven rotation in ITER, and intrinsic rotation became a topic of interest in the ITPA Transport Group. Through that connection, similar observations from DIII-D, TCV and JT-60U were added to the growing list. A database of intrinsic rotation observations was assembled with the goal of extrapolating to the expected values for ITER. Both dimensional and dimensionless scalings were developed and formed the backbone of the 2007 Nuclear Fusion paper. I gratefully acknowledge the important contributions to this paper from

  19. visCOS: An R-package to evaluate model performance of hydrological models

    Science.gov (United States)

    Klotz, Daniel; Herrnegger, Mathew; Wesemann, Johannes; Schulz, Karsten

    2016-04-01

    pivotal tool in model evaluation. They allow inferences about different systematic model-shortcomings and are an efficient way for communicating these in practice (Schulz et al., 2015). The evaluation and construction of such water balances is implemented with the presented package. During the (manual) calibration of a model or in the scope of model development, many model runs and iterations are necessary. Thus, users are often interested in comparing different model results in a visual way in order to learn about the model and to analyse parameter-changes on the output. A method to illuminate these differences and the evolution of changes is also included. References: • Gupta, H.V.; Wagener, T.; Liu, Y. (2008): Reconciling theory with observations: elements of a diagnostic approach to model evaluation, Hydrol. Process. 22, doi: 10.1002/hyp.6989. • Klemeš, V. (1986): Operational testing of hydrological simulation models, Hydrolog. Sci. J., doi: 10.1080/02626668609491024. • Kling, H.; Stanzel, P.; Fuchs, M.; and Nachtnebel, H. P. (2014): Performance of the COSERO precipitation-runoff model under non-stationary conditions in basins with different climates, Hydrolog. Sci. J., doi: 10.1080/02626667.2014.959956. • Schulz, K., Herrnegger, M., Wesemann, J., Klotz, D. Senoner, T. (2015): Kalibrierung COSERO - Mur für Pro Vis, Verbund Trading GmbH (Abteilung STG), final report, Institute of Water Management, Hydrology and Hydraulic Engineering, University of Natural Resources and Applied Life Sciences, Vienna, Austria, 217pp. • Zambrano-Bigiarini, M; Bellin, A. (2010): Comparing Goodness-of-fit Measures for Calibration of Models Focused on Extreme Events. European Geosciences Union (EGU), Geophysical Research Abstracts 14, EGU2012-11549-1.

  20. SIGNIFICADOS DE LA PALABRA “ESPARCIMIENTO” PARA ESTUDIANTES DE LA UNIVERSIDAD DE COSTA RICA Y DE MONTCLAIR STATE UNIVERSITY (THE MEANING OF THE WORD “LEISURE” FOR STUDENTS FROM THE UNIVERSITY OF COSTA RICA AND MONTCLAIR STATE UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Juniu Susana

    2010-04-01

    Full Text Available Resumen:El esparcimiento y la recreación frecuentemente se definen de manera individual y, por lo tanto, no se entienden o interpretan universalmente. Los diferentes contextos culturales pueden originar distintas definiciones o significados de esparcimiento. El reto de las personas que estudian el esparcimiento es interpretarlo de tal forma que ayude a las personas a entender acerca de su valor en la calidad de vida. Por consiguiente, este estudio examinó el significado de esparcimiento para estudiantes de un curso de estudios generales de la Universidad de Costa Rica (UCR y de Montclair State University (MSU, una universidad estatal del noreste de Estados Unidos, en el I ciclo lectivo del 2009. Las personas participantes fueron 388 estudiantes (149 hombres y 240 mujeres, promedio edad = 21 años, DE = 3.3 del curso de Actividad Deportiva, de carreras de grado de ambas universidades. El estudiantado contestó el Inventario de Significados de Esparcimiento (Schulz y Watkins, 2007. Este cuestionario incluye cuatro categorías: pasar el tiempo, escapar de presiones, tomar decisiones y lograr autorrealización. En términos generales, las diferencias estadísticamente significativas entre los grupos universitarios se relacionaron con el concepto de esparcimiento como “pasar el tiempo” y “tomar decisiones”. Las percepciones de esparcimiento como “escapar de presiones” y “lograr autorrealización” sólo fueron el resultado de diferencias estadísticas significativas de casos específicos. Los resultados indican que los estudiantes de MSU tienden más a percibir esparcimiento como “pasar el tiempo” y “tomar decisiones” que la contraparte costarricense.Abstract:Leisure and recreation are frequently defined personally and individually, and therefore not understood or interpreted universally. Different cultural contexts may result in diverse definitions and meanings of leisure. The challenge for leisure researchers is to

  1. Estimation of CO2 emissions from fossil fuel burning by using satellite measurements of co-emitted gases: a new method and its application to the European region

    Science.gov (United States)

    Berezin, Evgeny V.; Konovalov, Igor B.; Ciais, Philippe; Broquet, Gregoire

    2014-05-01

    ) measurements, respectively. Uncertainties in the CO2 emission estimates are evaluated by means of the Monte-Carlo experiment. In this study, our method is applied to the case of fossil fuel CO2 emissions from the European region. Taking into account that the uncertainty in available bottom-up estimates of the total CO2 emissions from that region is believed to be rather small, the case considered enables validation of our method, understanding its advantages and limitations, as well as examination of feasibility of its application to the world's regions with potentially much larger uncertainties in CO2 emissions. References: 1. Berezin, E. V., Konovalov, I. B., Ciais, P., Richter, A., Tao, S., Janssens-Maenhout, G., Beekmann, M., and Schulze, E.-D.: Multiannual changes of CO2 emissions in China: indirect estimates derived from satellite measurements of tropospheric NO2 columns, Atmos. Chem. Phys., 13, 9415-9438, doi:10.5194/acp-13-9415-2013, 2013. 2. Konovalov, I. B., Berezin, E. V., Ciais, P., Broquet, G., Beekmann, M., Hadji-Lazaro, J., Clerbaux, C., Andreae, M. O., Kaiser, J. W., and Schulze, E.-D.: Constraining CO2 emissions from open biomass burning by satellite observations of co-emitted species: a method and its application to wildfires in Siberia, submitted to Atmos. Chem. Phys.

  2. Revisiting an interdisciplinary hydrological modelling project. A socio-hydrology (?) example from the early 2000s

    Science.gov (United States)

    Seidl, Roman; Barthel, Roland

    2016-04-01

    Interdisciplinary scientific and societal knowledge plays an increasingly important role in global change research. Also, in the field of water resources interdisciplinarity as well as cooperation with stakeholders from outside academia have been recognized as important. In this contribution, we revisit an integrated regional modelling system (DANUBIA), which was developed by an interdisciplinary team of researchers and relied on stakeholder participation in the framework of the GLOWA-Danube project from 2001 to 2011 (Mauser and Prasch 2016). As the model was developed before the current increase in literature on participatory modelling and interdisciplinarity, we ask how a socio-hydrology approach would have helped and in what way it would have made the work different. The present contribution firstly presents the interdisciplinary concept of DANUBIA, mainly with focus on the integration of human behaviour in a spatially explicit, process-based numerical modelling system (Roland Barthel, Janisch, Schwarz, Trifkovic, Nickel, Schulz, and Mauser 2008; R. Barthel, Nickel, Meleg, Trifkovic, and Braun 2005). Secondly, we compare the approaches to interdisciplinarity in GLOWA-Danube with concepts and ideas presented by socio-hydrology. Thirdly, we frame DANUBIA and a review of key literature on socio-hydrology in the context of a survey among hydrologists (N = 184). This discussion is used to highlight gaps and opportunities of the socio-hydrology approach. We show that the interdisciplinary aspect of the project and the participatory process of stakeholder integration in DANUBIA were not entirely successful. However, important insights were gained and important lessons were learnt. Against the background of these experiences we feel that in its current state, socio-hydrology is still lacking a plan for knowledge integration. Moreover, we consider necessary that socio-hydrology takes into account the lessons learnt from these earlier examples of knowledge integration

  3. Composição e estrutura da vegetação de caatinga no sul do Piauí, Brasil

    Directory of Open Access Journals (Sweden)

    Mailson Pereira de Souza

    2017-06-01

    Full Text Available Visando contribuir para o conhecimento mais profundo a respeito da vegetação do sul do Piauí, e em especial às áreas de tensão ecológica, o presente trabalho objetivou inventariar, avaliando qualitativamente, o componente lenhoso de um trecho de Caatinga, no município de Bom Jesus, Piauí, Brasil. Para realização do levantamento foram alocadas 10 parcelas de 50x20 m (1000 m², totalizando 1 ha de área amostrada, dispostas de forma contíguas para minimizar os possíveis efeitos de borda da área. Foram amostrados os indivíduos lenhosos vivos com diâmetro à altura do peito (DAP ≥ 5 cm, independente da altura. No levantamento foram encontradas 11 famílias, 25 gêneros e 27 espécies. Destas, as que se destacaram com os maiores valores de IVI foram: Cenostigma macrophyllum Tul., Combretum duarteanum Cambess., Erythroxylum laetevirens O.E.Schulz, Campomanesia pubescens (Mart. ex DC. O. Berg., e Licania rigida Benth. O índice de diversidade de Shannon-Wiener (H’ foi de 2,7 nats.ind-1. Para todos os efeitos de comparações, observou-se que a área estudada encontra-se em bom estado de conservação, não se constatando evidências diretas de exploração, tão pouco resquícios de incêndios florestais, apesar da proximidade da área de estudo com a zona urbana da cidade de Bom Jesus do Piauí. O fragmento é um ecótono vegetacional, com predomínio de espécies típicas da Caatinga.Composition and structure  caatinga vegetation in south Piauí, BrazilAbstract: To contribute to the deeper knowledge of the southern Piaui vegetation, especially the areas of ecological tension, this study aimed to inventory and qualitatively assess the woody component of a Caatinga stretch in the municipality of Bom Jesus / PI,  Brazil. To perform the survey plots were allocated 10 50x20 m (1000 m² totaling 1 ha of sampled area, arranged contiguous way to minimize the possible edge effects area. They sampled the living woody individuals with

  4. Meliponini neotropicais: o gênero Ptilotrigona Moure (Hymenoptera, Apidae, Apinae

    Directory of Open Access Journals (Sweden)

    João M. F. Camargo

    2004-01-01

    Full Text Available O gênero neotropical de abelhas sem ferrão, Ptilotrigona Moure, 1951, é revisado. Três espécies são reconhecidas: Ptilotrigona occidentalis (Schulz, 1904, endêmica do NW da América do Sul - do NW do Equador até o sul de Darién -, e com uma população isolada na Península de Osa - Costa Rica; P. pereneae (Schwarz, 1943, endêmica do oeste da Amazônia, e P. lurida (Smith, 1854, amplamente distribuída na Amazônia. Ptilotrigona lurida e P. pereneae são as únicas abelhas sem ferrão que estocam pólen em associação com leveduras (Candida sp. e produzem pouco ou nenhum mel. Ninhos são descritos e ilustrados. Holótipos de Trigona suffragata Cockerell, 1922 (sin. de P. occidentalis e Trigona manni Cockerell, 1912, e exemplares de Trigona heideri Friese, 1900 (sins. de P. lurida, identificados por Friese, e um parátipo de Trigona (Tetragona heideri pereneae Schwarz, 1943, são estudados. Novo sinônimo: Ptilotrigona lurida (Smith, 1854 = Trigona mocsaryi lutea Friese, 1903 syn. nov. Na análise cladística, espécies de Camargoia Moure, 1989, e Tetragona Lepeletier & Serville, 1828, foram incluídas como grupos externos; a hipótese apresentada é a seguinte: ((((Ptilotrigona lurida, P. pereneae P. occidentalis((Camargoia nordestina, C. pilicornis C. camargoi Tetragona goettei. Uma chave de identificação para as espécies e outros aspectos bionômicos também são apresentados.Neotropical Meliponini: the genus Ptilotrigona Moure, (Hymenoptera, Apidae, Apinae. The Neotropical stingless bees genus Ptilotrigona Moure, 1951 is revised. Three species are recognized: Ptilotrigona occidentalis (Schulz, 1904, endemic to NW South America - from NW Ecuador to southern Darién -, and with one isolated population in Osa Peninsula - Costa Rica; P. pereneae (Schwarz, 1943, endemic to the western Amazon; and P. lurida (Smith, 1854, largely distributed in the Amazon region. Ptilotrigona lurida and P. pereneae are the only known stingless bees

  5. Contribution to the study of the textures of uranium rods prepared by sintering-extrusion, and their consequences on the thermal cycling behaviour; Contribution a l'etude des textures de barreaux d'uranium mis en forme par frittage-extrusion et leurs consequences sur le comportement au cyclage thermique

    Energy Technology Data Exchange (ETDEWEB)

    Peix, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-11-01

    Uranium rods prepared by sintering-extrusion in the {alpha} or {beta} phase (at various extrusion ratios) using slightly oxidised powders have been subjected to the thermal cycling test. At the same time, dilatometric and X-ray techniques have made it possible to determine the structures produced in these materials during their fabrication. A relationship is then proposed linking the texture to the increase in length on thermal cycling. 1. Two types of rods have been studied: Sintered-extruded in the {beta} phase: low density (88 per cent theoretical density), large grain-size and no preferential texture. Sintered-extruded in the {alpha} phase: high density (96 per cent theoretical density), fine grain with pronounced preferential texture. 2. After 1000 thermal cycles between 20 and 550 C, the increases in length are the following: 2 per cent for a uranium sintered-extruded in the {beta} phase (with surface cracking). between 14 and 56 per cent according to the extrusion ratio for on uranium sintered-extruded in the {alpha} phase (with no surface effects). 3. In the case of rods sintered-extruded in the {alpha} phase, determination of the pole figure using the Schulz reflection method showed the existence of two preferential orientations parallel to the direction of extrusion: one close to [100], the other close to [110]. By dilatometry it was then possible to measure quantitatively the proportion of each constituent in the overall texture and to show that an increase in the percentage of [100] occurs with increasing amounts of cold-working. 4. Finally, by comparing 2 and 3 it can be seen that the increases in length due to thermal cycling are connected to the percentage amounts of each component. It seems that the increases in length diminish as the percentage of [100] increases. On the other hand the behaviour of materials containing large amount of [110] is still far from clear. (author) [French] Des barreaux d'uranium realises par frittage-extrusion en phase

  6. Quantitative analysis of textures produced in a hot-extruded zirconium plate; Analyse quantitative des textures developpees dans une plaque de zirconium filee a chaud

    Energy Technology Data Exchange (ETDEWEB)

    Couterne, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires. Institut national des sciences et techniques nucleaires, laboratoire de metallurgie

    1967-01-01

    The textures produced in zirconium by the extrusion at 730 deg C of a cylindrical billet in the form of a plate having a rectangular cross-section, have been studied by the Schulz method using an isotropic standard. These textures have been determined both parallel to the plane of the plate and parallel to the plane of the sides, All the results are analyzed in a final discussion which makes it possible to show, in particular near the edges of the plate, that certain components of the textures observed in the two series of recordings are in fact aspects of the same texture seen from two different angles, It is shown furthermore that the zirconium thus shaped has cold-work textures and als recrystallisation textures formed after the preceding cold-working, If the observed textures are considered schematically, it can be see that two of these have already been described in the literature and are similar to those found in rolled products: these textures are such that the (0001) planes are inclined at 36 deg C and 60 deg C respectively with respect to a plan tangential to the curve (envelope of transverse flow rates) resulting from the extrusion geometry under consideration; the third texture is defined. by the fact that the (0001) plane is orthogonal to the exterior surfaces of the plate. The direction of extrusion associated with these planes and common to the three textures is of the type <1010>, Dilatometric tests have been carried out on samples taken both parallel and perpendicular to the extrusion direction, These tests show that the zirconium is dilatometrically anisotropic and that a plot of ({alpha}{sub v})-a against temperature shows a change of gradient at 400 deg C, this latter effect may be due to the change in the electronic configuration of the metal occurring at this temperature. (author) [French] Les textures conferees au zirconium par filage a chaud a 730 deg C d'une billette cylindrique sous forme d'une plaque de section rectangulaire, ont ete

  7. Quantitative analysis of textures produced in a hot-extruded zirconium plate; Analyse quantitative des textures developpees dans une plaque de zirconium filee a chaud

    Energy Technology Data Exchange (ETDEWEB)

    Couterne, J. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires. Institut national des sciences et techniques nucleaires, laboratoire de metallurgie

    1967-01-01

    The textures produced in zirconium by the extrusion at 730 deg C of a cylindrical billet in the form of a plate having a rectangular cross-section, have been studied by the Schulz method using an isotropic standard. These textures have been determined both parallel to the plane of the plate and parallel to the plane of the sides, All the results are analyzed in a final discussion which makes it possible to show, in particular near the edges of the plate, that certain components of the textures observed in the two series of recordings are in fact aspects of the same texture seen from two different angles, It is shown furthermore that the zirconium thus shaped has cold-work textures and als recrystallisation textures formed after the preceding cold-working, If the observed textures are considered schematically, it can be see that two of these have already been described in the literature and are similar to those found in rolled products: these textures are such that the (0001) planes are inclined at 36 deg C and 60 deg C respectively with respect to a plan tangential to the curve (envelope of transverse flow rates) resulting from the extrusion geometry under consideration; the third texture is defined. by the fact that the (0001) plane is orthogonal to the exterior surfaces of the plate. The direction of extrusion associated with these planes and common to the three textures is of the type <1010>, Dilatometric tests have been carried out on samples taken both parallel and perpendicular to the extrusion direction, These tests show that the zirconium is dilatometrically anisotropic and that a plot of ({alpha}{sub v})-a against temperature shows a change of gradient at 400 deg C, this latter effect may be due to the change in the electronic configuration of the metal occurring at this temperature. (author) [French] Les textures conferees au zirconium par filage a chaud a 730 deg C d'une billette cylindrique sous forme d'une plaque de section rectangulaire, ont

  8. Determination of Immunogenic Relevant Antigens in the Excretory-Secretory (ES Products and the Lysates of Ascaridia galli Larvae

    Directory of Open Access Journals (Sweden)

    S Saffi

    2008-04-01

    Full Text Available Background: Ascaridia galli, the largest nematode of small intestine of birds, especially the native poultry, may give rise to serious illness, pathological defects and economical losses even in modern poultry production systems. Although various measures have been undertaken to vaccinate poultry against A.galli, no satisfactory results were obtained so far. However, there is no report on the efficacy of excretory-secretory (ES proteins of A.galli larvae in immunization of poultry. Thus, the aim of the present research project was based on the use of the ES products of the larvae, in order to find the protective anti­gens.Methods: Five hundred native poultry were autopsied and adult A.galli was removed form their intestines. The eggs were harvested form the uterus of female worms and cultured at 25 ˚C in water containing 0.1 N sulphuric acid for almost a fort­night. The larvae were then freed mechanically and kept in Earl's salt solution for a few days. The supernatant solution of alive larvae containing the ES products of the larvae, as well as the sonicated alive and dead larvae, was analyzed by SDS-PAGE.Result: Many protein fractions of 15 kDa up to 200 kDa were demonstrated in lysate of these larvae. Using the serum of a hen, infected with a high numbers of A.galli, an immunogenic antigen was identified between 55 kDa to 72 kDa by Western blotting procedure.Conclusion: Finding the protein band between 55 and 72 kDa can be promising for preparation of vaccine, though more investigations are needed to prove the protective ability of this antigen.

  9. Use of a Novel Artificial Intelligence Platform on Mobile Devices to Assess Dosing Compliance in a Phase 2 Clinical Trial in Subjects With Schizophrenia.

    Science.gov (United States)

    Bain, Earle E; Shafner, Laura; Walling, David P; Othman, Ahmed A; Chuang-Stein, Christy; Hinkle, John; Hanina, Adam

    2017-02-21

    Accurately monitoring and collecting drug adherence data can allow for better understanding and interpretation of the outcomes of clinical trials. Most clinical trials use a combination of pill counts and self-reported data to measure drug adherence, despite the drawbacks of relying on these types of indirect measures. It is assumed that doses are taken, but the exact timing of these events is often incomplete and imprecise. The objective of this pilot study was to evaluate the use of a novel artificial intelligence (AI) platform (AiCure) on mobile devices for measuring medication adherence, compared with modified directly observed therapy (mDOT) in a substudy of a Phase 2 trial of the α7 nicotinic receptor agonist (ABT-126) in subjects with schizophrenia. AI platform generated adherence measures were compared with adherence inferred from drug concentration measurements. The mean cumulative pharmacokinetic adherence over 24 weeks was 89.7% (standard deviation [SD] 24.92) for subjects receiving ABT-126 who were monitored using the AI platform, compared with 71.9% (SD 39.81) for subjects receiving ABT-126 who were monitored by mDOT. The difference was 17.9% (95% CI -2 to 37.7; P=.08). Using drug levels, this substudy demonstrates the potential of AI platforms to increase adherence, rapidly detect nonadherence, and predict future nonadherence. Subjects monitored using the AI platform demonstrated a percentage change in adherence of 25% over the mDOT group. Subjects were able to use the technology successfully for up to 6 months in an ambulatory setting with early termination rates that are comparable to subjects outside of the substudy. ClinicalTrials.gov NCT01655680 https://clinicaltrials.gov/ct2/show/NCT01655680?term=NCT01655680. ©Earle E Bain, Laura Shafner, David P Walling, Ahmed A Othman, Christy Chuang-Stein, John Hinkle, Adam Hanina. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 21.02.2017.

  10. Homer Wheelon, M.D., physiologist, artist, and poet: origins of the tailpieces in journals of the American Physiological Society.

    Science.gov (United States)

    Schramm, Lawrence P; Schramm, Diana C; Jackson, F Wilson

    2006-12-01

    Since 1953, illustrations have been inserted as "tailpieces" at the ends of articles in The American Journal of Physiology and The Journal of Applied Physiology. The drawings were made by Homer Wheelon, a member of the American Physiological Society from 1919 until his death in 1960. Forty-five years after his death, Wheelon is unknown, but he contributed 32 publications to the medical literature and trained J. Earl Thomas, an important 20th century gastrointestinal physiologist. Wheelon was born into poverty in 1883 to itinerant Methodist preachers, circumstances that guided his education and career choices. Throughout his life, Wheelon exhibited a fondness and talent for art and photography and an unusual breadth of intellectual interests and knowledge. Wheelon received a bachelor's degree from the University of Washington, then studied at the University of Oregon, Northwestern University, and St. Louis University. Earning his M.D. from St. Louis University and assuming a faculty position there, Wheelon and his graduate student, Thomas, conducted widely recognized gastrointestinal research. Returning to Seattle in 1921, Wheelon became a highly respected physician and hospital administrator, but he also found time to indulge his interest in visual art and poetry. In 1933, inspired by observing a rabbit being used in a pregnancy test, Wheelon began to write and illustrate an epic, 322-page poem, Rabbit No. 202, illustrations from which became the journals' tailpieces. The present study traces Wheelon's personal life and scientific career in an attempt to understand this complex man and the origins of his unusual poem and its drawings.

  11. CD147 is increased in HCC cells under starvation and reduces cell death through upregulating p-mTOR in vitro.

    Science.gov (United States)

    Gou, Xingchun; Tang, Xu; Kong, Derek Kai; He, Xinying; Gao, Xingchun; Guo, Na; Hu, Zhifang; Zhao, Zhaohua; Chen, Yanke

    2016-01-01

    Transarterial chemoembolization (TACE) is the standard of care for treatment of intermediate hepatocellular carcinoma (HCC), however, key molecules involved in HCC cell survival and tumor metastasis post-TACE remain unclear. CD147 is a member of the immunoglobulin superfamily that is overexpressed on the surface of HCC cells and is associated with malignant potential and poor prognosis in HCC patients. In this study, using an Earle's Balanced Salt Solution medium culture model that mimics nutrient deprivation induced by TACE, we investigated the regulation of CD147 expression on HCC cells under starvation conditions and its functional effects on HCC cell death. During early stages of starvation, the expression of CD147 was considerably upregulated in SMMC7721, HepG2 and HCC9204 hepatoma cell lines at the protein levels. Downregulation of CD147 by specific small interfering RNA (siRNA) significantly promoted starvation-induced cell death. In addition, CD147 siRNA-transfected SMMC7721 cells demonstrated significantly increased levels of both apoptosis and autophagy as compared to cells transfected with control siRNA under starvation conditions, whereas no difference was observed between the two treatment groups under normal culture conditions. Furthermore, silencing of CD147 resulted in a remarkable downregulation of phosphorylated mammalian target of rapamycin (p-mTOR) in starved SMMC7721 cells. Finally, the combined treatment of starvation and anti-CD147 monoclonal antibody exhibited a synergistic HCC cell killing effect. Our study suggests that upregulation of CD147 under starvation may reduce hepatoma cell death by modulating both apoptosis and autophagy through mTOR signaling, and that CD147 may be a novel potential molecular target to improve the efficacy of TACE.

  12. International perspectives on work-family policies: lessons from the world's most competitive economies.

    Science.gov (United States)

    Earle, Alison; Mokomane, Zitha; Heymann, Jody

    2011-01-01

    The United States does not guarantee families a wide range of supportive workplace policies such as paid maternity and paternity leave or paid leave to care for sick children. Proposals to provide such benefits are invariably met with the complaint that the costs would reduce employment and undermine the international competitiveness of American businesses. In this article, Alison Earle, Zitha Mokomane, and Jody Heymann explore whether paid leave and other work-family policies that support children's development exist in countries that are economically competitive and have low unemployment rates. Their data show that the answer is yes. Using indicators of competitiveness gathered by the World Economic Forum, the authors identify fifteen countries, including the United States, that have been among the top twenty countries in competitiveness rankings for at least eight of ten years. To this group they add China and India, both rising competitors in the global economy. They find that every one of these countries, except the United States, guarantees some form of paid leave for new mothers as well as annual leave. And all but Switzerland and the United States guarantee paid leave for new fathers. The authors perform a similar exercise to identify thirteen advanced countries with consistently low unemployment rates, again including the United States. The majority of these countries provide paid leave for new mothers, paid leave for new fathers, paid leave to care for children's health care needs, breast-feeding breaks, paid vacation leave, and a weekly day of rest. Of these, the United States guarantees only breast-feeding breaks (part of the recently passed health care legislation). The authors' global examination of the most competitive economies as well as the economies with low unemployment rates makes clear that ensuring that all parents are available to care for their children's healthy development does not preclude a country from being highly competitive

  13. ESTUDIO COMPARATIVO DE MODELOS DE GESTIÓN DEL PROCESO DE DESARROLLO DE PRODUCTOS ALIMENTICIOS

    Directory of Open Access Journals (Sweden)

    G. Rossetti

    2014-06-01

    Full Text Available Debido al aumento de los productos ofrecidos en el mercado y a la reducción del tiempo de vida de los mismos, el Proceso de Desarrollo de Productos (PDP es considerado un proceso de negocio cada vez más importante para la competitividad de las empresas. Los productos deben gestionarse de modo que se introduzcan rápidamente en el mercado, satisfagan mejor las necesidades de los clientes, sean más fáciles de fabricar, resulten atractivos en el mercado y aseguren beneficios para las empresas. Desde el inicio del siglo XX, los principales estímulos del desarrollo de nuevos productos en el sector alimenticio se encuentran relacionados con el desarrollo e incorporación de innovación tecnológica. Actualmente, la evolución del PDP ocurre principalmente debido a la preocupación de las industrias en mejorar su desempeño económico, y al mismo tiempo aumentar la calidad de sus respectivos productos y atender las exigencias de los consumidores. A pesar de existir estudios que buscan estandarizar el desarrollo de productos alimenticios, la implementación de modelos de PDP es muy incipiente. El presente trabajo tiene como objetivo analizar los métodos desarrollados por distintos autores acerca del PDP orientado a la industria alimenticia (PDPA y establecer una comparación con el modelo general propuesto por Rozenfeld et al. (1. Entre los modelos actuales se destacan los siguientes: Fuller (2; Rudolph (3; Earle (4; Polignano y Drumond (5 y Penso (6. Dichos autores establecen secuencias de fases estructuradas que facilitan la comprensión y la realización del desarrollo de un nuevo producto en la industria de alimentos.

  14. In pursuit of a self-sustaining college alcohol intervention: Deploying gamified PNF in the real world.

    Science.gov (United States)

    Earle, Andrew M; LaBrie, Joseph W; Boyle, Sarah C; Smith, Daniel

    2018-05-01

    Our recent work (Boyle, Earle, LaBrie, & Smith, 2017) showed that the efficacy of personalized normative feedback-based (PNF) college alcohol interventions can be improved through the addition of gamified elements including points, chance, competition, and personal avatars. However, participants in that study were compensated with subject pool credit. In the current study, we piloted an upgraded, smartphone-based version of the game, which was designed to be truly self-sustaining (i.e., engaging enough that students play voluntarily without the presence of external motivators). First-year students were invited to play the game weekly for six rounds, with participants submitting and voting on their own questions each week and receiving a novel type of feedback in addition to standard descriptive PNF: opposite peers' judgments of participants' self-reported drinking behavior, or reflective norms. With no play-based incentives, 222 first-year college students voluntarily played the game, CampusGANDR. ANCOVA models revealed that, relative to participants randomized to receive feedback on control topics during the three intervention rounds, those who received both descriptive and reflective feedback on peer alcohol use had significantly reduced normative perceptions and reduced alcohol use two months post intervention. This was especially true among heavy drinkers. The results suggest that our gamified "GANDR" approach shows promise as a self-sustaining intervention and, further, that high-risk drinkers may benefit disproportionately from this methodology. Thus, self-sustaining interventions represent an encouraging avenue for future research and development and may hold the potential to impact risky college drinking on a large scale. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Energy resources and the environment. [6 essays

    Energy Technology Data Exchange (ETDEWEB)

    Lenihan, J; Fletcher, W W [eds.

    1975-01-01

    Exploitation of energy has some impact on the environment. Six essays are presented to examine the variety of problems: (1) Sir Samuel Curran, in Energy and the Needs of Man, concludes that techniques to produce new energy sources will be found, bur conservation and the population explosion must be seriously examined; (2) Dr. Earl Cook, in Flow of Energy Through Technological Society, shows where energy comes from, how it is used and how it returns to the environment; he emphasizes the inefficiency of many energy conversion processes in consequence of the Second law of Thermodynamics; (3) Dr. Andrew Parteous, in Economical Use of Energy and Materials, explains energy not only used in heating, lighting, and transport, but in industry; his accounting of energy shows waste, and he stresses recycling and recovering the energy in domestic waste; (4) Sir Frank McFadzean, in Energy--the International Scene, examines the interplay of economics, technology, and politics in the oil industry; he suggests that more mature international leadership is needed to overcome the current difficulties facing producers and consumers; (5) J. D. Dunster, in The Atom and the Environment, examines the environmental impact of nuclear energy where the safety standards are more strenuous, but are feared more; he is a proponent of nuclear energy, but says an overall energy policy, balancing environmental factors against economic and political considerations, is needed; Dr. B. J. Brinkworth, in Direct Use of Solar Energy, reminds us that the Sun is the ultimate source of energy, and says solar energy can be exploited globally without damaging the environment. (MCW)

  16. Early Intervention in Bipolar Disorder.

    Science.gov (United States)

    Vieta, Eduard; Salagre, Estela; Grande, Iria; Carvalho, André F; Fernandes, Brisa S; Berk, Michael; Birmaher, Boris; Tohen, Mauricio; Suppes, Trisha

    2018-05-01

    Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and usually has its onset during youth. Its chronic course is associated with high rates of morbidity and mortality, making bipolar disorder one of the main causes of disability among young and working-age people. The implementation of early intervention strategies may help to change the outcome of the illness and avert potentially irreversible harm to patients with bipolar disorder, as early phases may be more responsive to treatment and may need less aggressive therapies. Early intervention in bipolar disorder is gaining momentum. Current evidence emerging from longitudinal studies indicates that parental early-onset bipolar disorder is the most consistent risk factor for bipolar disorder. Longitudinal studies also indicate that a full-blown manic episode is often preceded by a variety of prodromal symptoms, particularly subsyndromal manic symptoms, therefore supporting the existence of an at-risk state in bipolar disorder that could be targeted through early intervention. There are also identifiable risk factors that influence the course of bipolar disorder, some of them potentially modifiable. Valid biomarkers or diagnosis tools to help clinicians identify individuals at high risk of conversion to bipolar disorder are still lacking, although there are some promising early results. Pending more solid evidence on the best treatment strategy in early phases of bipolar disorder, physicians should carefully weigh the risks and benefits of each intervention. Further studies will provide the evidence needed to finish shaping the concept of early intervention. AJP AT 175 Remembering Our Past As We Envision Our Future April 1925: Interpretations of Manic-Depressive Phases Earl Bond and G.E. Partridge reviewed a number of patients with manic-depressive illness in search of a unifying endo-psychic conflict. They concluded that understanding either phase of illness was "elusive" and

  17. DIRECT AND INDIRECT FLUORESCENT-ANTIBODY TECHNIQUES FOR THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA GROUP OF AGENTS1

    Science.gov (United States)

    Ross, Martin R.; Borman, Earle K.

    1963-01-01

    Ross, Martin R. (Connecticut State Department of Health, Hartford) and Earle K. Borman. Direct and indirect fluorescent-antibody techniques for the psittacosis-lymphogranuloma venereum-trachoma group of agents. J. Bacteriol. 85:851–858. 1963.—Direct and indirect fluorescent-antibody (FA) techniques were developed for the detection of group antigen in infected tissue cultures and the titration of group antibody in human antiserum. The growth of the agent of meningopneumonitis (MP) in mouse embryo lung cell monolayers was followed by infectivity and complement-fixing (CF) antigen titrations, and cytological examination of FA stained cultures. Although infectivity and CF antigen reached a peak at 2 days and remained constant for an additional 3 days, only cells tested 2 to 3 days after infection were suitable for FA staining with labeled anti-MP serum because of excessive artifacts in the older cultures. Fluorescein isothiocyanate-labeled rooster and guinea pig anti-MP serums and human antipsittacosis serums were titrated in direct FA and hemagglutination-inhibition (HI) tests. The rooster conjugate showed brighter staining and higher antibody titers than the guinea pig or human conjugates and was more effective in detecting minimal amounts of virus antigen. FA staining reactions with 1 and 2 units of labeled rooster serum were inhibited by unlabeled rooster serum but clear-cut inhibition with human antipsittacosis serum could not be demonstrated. The indirect FA technique was successfully used for the titration of group antibody in human serum. A comparison of the indirect FA, HI, and CF tests showed the indirect FA technique to be intermediate in sensitivity between the HI and CF tests. None of the three tests showed significant cross reactions with human serums reactive for influenza A and B; parainfluenza 1, 2, and 3; respiratory syncytial virus; Q fever; or the primary atypical pneumonia agent. PMID:14044954

  18. Violations of Grice`s Maxims in The Prince and the Pauper Movie

    Directory of Open Access Journals (Sweden)

    Antonius Waget

    2016-12-01

    Full Text Available Proper responses must be provided interlocutors to make onversation productive and meaningful. However, interlocutors do not always provide proper responses because they do not even know conversation rules. Grice coins 4 maxims as general rules to govern daily conversation. The maxims are Quantity, Quality, Relevance, and Manner. Conversation occurs in the real daily interaction also in arts including movies. The Prince and the Pauper movie is one of the media for human daily conversation. Some parts of the movie contains violations of Grice`s maxims by the characters. Based on this background, the writer intends to explore violations ofGrice’s maxims in the movie and analyze the purposes of the violations. To achieve these objectives, the writer formulates two research problems: (1 Which of Grice`s maxims are violated by the addressees in The Prince and the Pauper movie? (2 For what purposes do the addressees violate the maxims? The base of this research is a movie script as document. Thus, the writer uses document analysis as the method of this research. Grounded on the analysis, the writer finds that the characters, especially Prince, Tom Canty, King, and the Earl of Hertford in the movie dialogues violate the four of Grice`s maxims. When failing to provide sufficient information, telling lie to their addressers, providing irrelevant glosses, and failing to be true, brief, univocal, and orderly, they respectively violate maxims of Quantity, Quality, Relevance, and Manner. Moreover, the writer finds that the characters violate the maxims in order to mislead the counterparts, be polite, save face, avoid discussion, and communicate self-interest.   DOI: https://doi.org/10.24071/llt.2015.180101

  19. Tropical Cyclone Induced Air-Sea Interactions Over Oceanic Fronts

    Science.gov (United States)

    Shay, L. K.

    2012-12-01

    Recent severe tropical cyclones underscore the inherent importance of warm background ocean fronts and their interactions with the atmospheric boundary layer. Central to the question of heat and moisture fluxes, the amount of heat available to the tropical cyclone is predicated by the initial mixed layer depth and strength of the stratification that essentially set the level of entrainment mixing at the base of the mixed layer. In oceanic regimes where the ocean mixed layers are thin, shear-induced mixing tends to cool the upper ocean to form cold wakes which reduces the air-sea fluxes. This is an example of negative feedback. By contrast, in regimes where the ocean mixed layers are deep (usually along the western part of the gyres), warm water advection by the nearly steady currents reduces the levels of turbulent mixing by shear instabilities. As these strong near-inertial shears are arrested, more heat and moisture transfers are available through the enthalpy fluxes (typically 1 to 1.5 kW m-2) into the hurricane boundary layer. When tropical cyclones move into favorable or neutral atmospheric conditions, tropical cyclones have a tendency to rapidly intensify as observed over the Gulf of Mexico during Isidore and Lili in 2002, Katrina, Rita and Wilma in 2005, Dean and Felix in 2007 in the Caribbean Sea, and Earl in 2010 just north of the Caribbean Islands. To predict these tropical cyclone deepening (as well as weakening) cycles, coupled models must have ocean models with realistic ocean conditions and accurate air-sea and vertical mixing parameterizations. Thus, to constrain these models, having complete 3-D ocean profiles juxtaposed with atmospheric profiler measurements prior, during and subsequent to passage is an absolute necessity framed within regional scale satellite derived fields.

  20. Desenvolvimento de Eurytrema coelomaticum (Giard & Billet (Digenea, Dicrocoeliidae em Bradybaena similaris (Férussac (Gastropoda, Xanthonychidae Development of Eurytrema coelomaticum (Giard & Billet (Digenea, Dicrocoeliidae in Bradybaena similaris (Férussac (Gastropoda, Xanthonychidae

    Directory of Open Access Journals (Sweden)

    Solange Viana Paschoal Blanco Brandolini

    2001-06-01

    Full Text Available To follow the larval developmenl of Eurytrema coelomaticum (Giard & Billet, 1892 in Bradybaena similaris (Férussac, 1821 snails were separated in three classes using the shell diameter: Class A (14.5-10.2 mm, Class B (10.1-6.9 mm and Class C (6.8-2.6 mm. Only snails belonging to classes A and B acquired the infection. Specimens of E. coelomaticum removed from the pancreatic ducts were exposed to three physiological solutions: Earle, Locke and saline 0.85%, to obtain eggs for the experimental infections, The Locke solution induced the best egg release. The route of migration the intramolluscan development of E. coelomaticum was studied with the aid of histology. The minimal period of intramolluscan developmenl, ending at the expelling of daughter sporocysts, was 107 days for the snails infected in March, and 79 days for the snails infected in November. The Student "t" test and the Chi-square test showed a significant difference (α = 5% between the two periods, although the mean temperature registered during the experiments did not significantly differed (α = 5%. The elimination of daughter sporocysts occurred through the snail's pneumostome, and always at night. Most sporocysts were eliminated at intervals that varied between one to three days, without regularity. The time of elimination of the daughter sporocysts was different for the two infection period studied: 12 weeks for the snails infected in March, and three weeks for those infected in November. Positive correlation between the number of sporocysts expelled by the snail host and higher temperatures registered in the laboratory was observed. This correlation was more evident in November infection.

  1. The best advice I ever got.

    Science.gov (United States)

    Wademan, Daisy

    2005-01-01

    A young manager faces an impasse in his career. He goes to see his mentor at the company, who closes the office door, offers the young man a chair, recounts a few war stories, and serves up a few specific pointers about the problem at hand. Then, just as the young manager is getting up to leave, the elder executive adds one small kernel of avuncular wisdom--which the junior manager carries with him through the rest of his career. Such is the nature of business advice. Or is it? The six essays in this article suggest otherwise. Few of the leaders who tell their stories here got their best advice in stereotypical form, as an aphorism or a platitude. For Ogilvy & Mather chief Shelly Lazarus, profound insight came from a remark aimed at relieving the tension of the moment. For Novartis CEO Daniel Vasella, it was an apt comment, made on a snowy day, back when he was a medical resident. For publishing magnate Earl Graves and Starwood Hotels' Barry Sternlicht, advice they received about trust from early bosses took on ever deeper and more practical meaning as their careers progressed. For Goldman Sachs chairman Henry Paulson, Jr., it was as much his father's example as it was a specific piece of advice his father handed down to him. And fashion designer Liz Lange rejects the very notion that there's inherent wisdom in accepting other people's advice. As these stories demonstrate, people find wisdom when they least expect to, and they never really know what piece of advice will transcend the moment, profoundly affecting how they later make decisions, evaluate people, and examine--and reexamine--their own actions.

  2. [The disgrace of Antoine Daquin, first physician of Louis XIV (1693)].

    Science.gov (United States)

    Peumery, J J

    1996-12-01

    Antoine Daquin, Principal Physician of Louis XIV and Earl of Jouy-en-Josas, was born in Paris. He was the son of Louis-Henri Daquin, Physician to Queen Marie de Médicis; his paternal grandfather, born in the Jewish religion, became converted to catholicism at Aquino, in Italy, whence his name d'Aquin, then Daquin. A. Daquin studied to be a doctor at Montpellier and graduated on 18 May 1648. He married Marguerite Gayant, Antoine Vallot's niece, Antoine Vallot being the Principal Physician of Louis XIV. This relationship permitted him to get the position of Principal Physician of the Queen, then, after Vallot's death, to succeed him, on 18 April 1672, as Principal Physician of the King. The kindliness of the King's mistress, Mme de Montespan, helped him in that appointment. Daquin was a good doctor, he turned out awkward: "great courtier, but rich, miser, grasping, wanting to establish his family anyway" said the Duc de Saint-Simon. He dared ask the King for the Archbishopric of Tours for his son: "it was the rock on which he broke up" said again Saint-Simon. On 2 November 1693, the comte de Pontchartrain came to his home by order of the King, to tell him, he was ordered to retire from Court without delay. It was forbidden him to come back or to write to the King. Guy-Crescent Fagon was designated "Premier Médecin" instead of him; but Fagon had worked at the undoing of Daquin, with a view to robbing him of his position, with the complicity of the King's new mistress, Mme de Maintenon. After his disgrace, Daquin retired probably to Moulins; he died obscurely in Vichy, on 17 May 1696. Today, Daquin is regarded as a victim of intrigues of Court, which explains his celebrity.

  3. Learning to See the City Again: Ethnographic Visions of Gender, Class, and Space in Ho Chi Minh City

    Directory of Open Access Journals (Sweden)

    Erik Harms

    2015-06-01

    Full Text Available Ann Marie Leshkowich. Essential Trade: Vietnamese Women in a Changing Marketplace. University of Hawai'i Press, 2014. 272 pp. $55 (cloth, $25 (paper. Kimberly Kay Hoang. Dealing in Desire: Asian Ascendancy, Western Decline, and the Hidden Currencies of Global Sex Work. University of California Press, 2015. 248 pp. $65 (cloth, $30 (paper/ebook. Catherine Earl. Vietnam’s New Middle Classes: Gender, Career, City. NIAS Press, 2014. 320 pp. £50 (cloth, £18 (paper. Annette Miae Kim. Sidewalk City: Remapping Public Space in Ho Chi Minh City. University of Chicago Press, 2015. 264 pp. $45 (cloth, $7–$36 (ebook. In addition to looking at gendered space, then, understanding a city requires considering the dynamic relationship between the seen and the unseen. And in order to understand this relationship, we need more than preconceived pronouncements about how the city works, or about how gender and class work on space. Rather, we need rich, fine-grained ethnography that traces the dynamic intersections of gender, space, and class in a city. To do such ethnography properly requires peering beyond the surface appearances of the city and listening intently to the everyday lives lived within it. The four new ethnographic perspectives on gender, class, and space in Ho Chi Minh City discussed in this essay all offer ways to see the city again. Three of them do this by looking at class and gender, and one does it by rethinking how we make maps; two of them are by anthropologists, one by a sociologist, and one by an urban planner. But they share one thing in common: all of them hone their keen vision with the aid of ethnography...

  4. Establishment and partial characterization of a cell line from burbot Lota lota maculosa: susceptibility to IHNV, IPNV and VHSV.

    Science.gov (United States)

    Polinski, Mark P; Drennan, John D; Batts, William N; Ireland, Susan C; Cain, Kenneth D

    2010-05-18

    This study describes the development and partial characterization of a continuous fibroblastic-like cell line (BEF-1) developed from late stage embryos of North American burbot Lota lota maculosa. This cell line has been maintained for over 5 yr and 100 passages in vitro. Cells were cultured using Eagle's minimum essential medium with Earle's salts (MEM) supplemented with GlutaMAX, and 10% fetal bovine serum (FBS), pH 7.4. The addition of penicillin-streptomycin-neomycin (PSN) antibiotic mixture (0.05, 0.05, 0.1 mg m(-1), respectively) did not negatively influence cell replication; however, the antimycotic FungizoneTM (2.5 microg m(-1), amphotericin B) caused cell rounding and resulted in a severe decrease in cell proliferation. Optimal incubation temperature has been observed between 15 and 23 degrees C, and at these temperatures cultures are routinely passed using standard trypsinization methods every 5 to 7 d at a split ratio of 1:3 or 1:4. The cell line was susceptible to isolates of the M and U North American genotypes of infectious hematopoietic necrosis virus (IHNV), and to isolates of genotypes I, IVa, and IVb of viral hemorrhagic septicemia virus (VHSV). In contrast, the cell line was refractory to infection by 2 North American isolates of infectious pancreatic necrosis virus (IPNV) from serotypes A1 and A9. This cell line provides a new laboratory tool, will allow further investigation into viral diseases of burbot and possibly other species, and is the first immortalized cell line reported from a species in the Gadidae (cod) family.

  5. Is there a role for a test controller in the development of new ATC equipment?

    Science.gov (United States)

    Westrum, Ron

    1994-01-01

    Earl Wiener points out that human factors problems fixed during the R & D stage are paid for once. When they are not fixed during R & D, they are then paid for every day. How users are involved in the R & D process to assist in developing equipment is a critical issue. Effective involvement can produce real improvements. Ineffective involvement can produce inefficient kludges or systems that are actually dangerous. The underlying problem is the management of information and ideas. To develop a really generative system a great deal would have to change in the way that the FAA innovates. Use of test controllers would solve only some of the problems. For instance, we have cockpit resource management now for pilots; we may have it soon for controllers. But the management of ideas in the innovation process also needs intellectual resource management. Simply involving users is not enough. Brought in at the wrong point in the development process, users can block or compromise innovation. User involvement must be carefully considered. A test controller may be one solution to this problem. It might be necessary to have several kinds of test controllers (en route versus TRACON, for instance). No doubt further problems would surface in getting test controllers into operation. I would recommend that the FAA engage in a series of case studies of controller involvement in the innovation process. A systematic comparison of effective and ineffective cases would do much to clarify what we ought to do in the future. Unfortunately, I have been unable to find any cases where test controllers have been used. Perhaps we need to create some, to see how they work.

  6. Hurricane Imaging Radiometer (HIRAD) Observations of Brightness Temperatures and Ocean Surface Wind Speed and Rain Rate During NASA's GRIP and HS3 Campaigns

    Science.gov (United States)

    Miller, Timothy L.; James, M. W.; Roberts, J. B.; Jones, W. L.; Biswas, S.; Ruf, C. S.; Uhlhorn, E. W.; Atlas, R.; Black, P.; Albers, C.

    2012-01-01

    HIRAD flew on high-altitude aircraft over Earl and Karl during NASA s GRIP (Genesis and Rapid Intensification Processes) campaign in August - September of 2010, and plans to fly over Atlantic tropical cyclones in September of 2012 as part of the Hurricane and Severe Storm Sentinel (HS3) mission. HIRAD is a new C-band radiometer using a synthetic thinned array radiometer (STAR) technology to obtain spatial resolution of approximately 2 km, out to roughly 30 km each side of nadir. By obtaining measurements of emissions at 4, 5, 6, and 6.6 GHz, observations of ocean surface wind speed and rain rate can be retrieved. The physical retrieval technique has been used for many years by precursor instruments, including the Stepped Frequency Microwave Radiometer (SFMR), which has been flying on the NOAA and USAF hurricane reconnaissance aircraft for several years to obtain observations within a single footprint at nadir angle. Results from the flights during the GRIP and HS3 campaigns will be shown, including images of brightness temperatures, wind speed, and rain rate. Comparisons will be made with observations from other instruments on the campaigns, for which HIRAD observations are either directly comparable or are complementary. Features such as storm eye and eye-wall, location of storm wind and rain maxima, and indications of dynamical features such as the merging of a weaker outer wind/rain maximum with the main vortex may be seen in the data. Potential impacts on operational ocean surface wind analyses and on numerical weather forecasts will also be discussed.

  7. Job Crafting: Older Workers’ Mechanism for Maintaining Person-Job Fit

    Science.gov (United States)

    Wong, Carol M.; Tetrick, Lois E.

    2017-01-01

    Aging at work is a dynamic process. As individuals age, their motives, abilities and values change as suggested by life-span development theories (Lang and Carstensen, 2002; Kanfer and Ackerman, 2004). Their growth and extrinsic motives weaken while intrinsic motives increase (Kooij et al., 2011), which may result in workers investing their resources in different areas accordingly. However, there is significant individual variability in aging trajectories (Hedge et al., 2006). In addition, the changing nature of work, the evolving job demands, as well as the available opportunities at work may no longer be suitable for older workers, increasing the likelihood of person-job misfit. The potential misfit may, in turn, impact how older workers perceive themselves on the job, which leads to conflicting work identities. With the traditional job redesign approach being a top-down process, it is often difficult for organizations to take individual needs and skills into consideration and tailor jobs for every employee (Berg et al., 2010). Therefore, job crafting, being an individualized process initiated by employees themselves, can be a particularly valuable mechanism for older workers to realign and enhance their demands-abilities and needs-supplies fit. Through job crafting, employees can exert personal agency and make changes to the task, social and cognitive aspects of their jobs with the goal of improving their work experience (Wrzesniewski and Dutton, 2001). Building on the Life Span Theory of Control (Heckhausen and Schulz, 1995), we posit that job crafting, particularly cognitive crafting, will be of increasing value as employees age. Through reframing how they think of their job and choosing to emphasize job features that are personally meaningful, older workers can optimize their resources to proactively redesign their jobs and maintain congruent, positive work identities. PMID:28943859

  8. Radioimmunological analysis of circadian rhythms of cortisol and melatonin in saliva

    International Nuclear Information System (INIS)

    Demel, A.W.

    1990-12-01

    Since blood cortisol (F) and melatonin (MLT) display a circadian secretion pattern and since the saliva concentration of this hormones is an excellent indicator of its blood levels the measurement of salivary F and MLT may be used for examining circadian rhythmicity. In this study the relationship between salivary F and MLT was explored. For this purpose it was necessary first to establish and validate a radioimmunoassay for F in saliva: salivary F was determined by a direct radioimmunoassay using cortisol-3-(O-carboxymethyl) oximino-(2-( 125 I)iodohistamin) as tracer and cortisol-3-CMO-BSA antiserum. The parallel measurement of F levels in saliva and serum of adults gave an excellent correlation (r=0.87, p 0.00956x ). Serum F was assayed on the Abott TDX-System using a radioimmunofluorescence method. Secondly, using this assay the circadian saliva F pattern was determined as well as the pattern of salivary MLT in 9 young, healthy volunteers. For saliva MLT estimations a previously published method was applied (Schulz et al 1990). Using a computerized program (RHYTHM) written by Eve v. Cauter (1979), the hormone data of each individuum were examined for circadian rhythmicity and its acrophase (time of occurrence of the maximum of a sinusoid fitted to the data). The F acrophase occurred between 7:00 and 12:00 h (mean: 3:33 h, SD: 104.4 min). The easy stress-free non invasive nature of saliva collection makes saliva to one of the most accessible body fluids and of high value in studying the circadian system in healthy humans as well as in infants, children, pregnant women and anaemic patients. Measurements of salivary F and MLT may help to elucidate not only the circadian rhythms of these hormones under normal and pathological conditions but it may also provide insight in physiology and pathology of the circadian system in general. (author)

  9. Radioimmunological analysis of circadian rhythms of cortisol and melatonin in saliva

    International Nuclear Information System (INIS)

    Demel, A.W.

    1990-12-01

    Since blood cortisol (F) and melatonin (MLT) display a circadian secretion pattern and since the saliva concentration of this hormones is an excellent indicator of its blood levels the measurement of salivary F and MLT may be user for examining circadian rhythmicity. In this study the relationship between salivary F and MLT was explored. For this purpose it was necessary first to establish and validate a radioimmunoassay for F in saliva: salivary F was determined by a direct radioimmunoassay using cortisol-3-(O-carb oxymethyl) oximino-(2-( 125 I)iodohistamin) as tracer and cortisol-3-CMO-BSA antiserum. The parallel measurement of F levels in saliva and serum of adults gave an excellent correlation (r=0.87, p 0.00956x ). Serum F was assayed on the Abott TDX-System using a radioimmunofluorescence method. Secondly, using this assay the circadian saliva F pattern was determined as well as the pattern of salivary MLT in 9 young, healthy volunteers. For saliva MLT estimations a previously published method was applied (SCHULZ et al 1990). Using a computerized program (RHYTHM) written by EVE v. CAUTER (1979), the hormone data of each individuum were examined for circadian rhythmicity and its acrophase (time of occurence of the maximum of a sinusoid fitted to the data). The F acrophase occured between 7:00 and 12:00 h (Mean: 3:33 h, SD: 104.4 min). The easy stress-free non invasive nature of saliva collection makes saliva to one of the most accessible body fluids and of high value in studying the circadian system in healthy humans as well as in infants, children, pregnant women and anaemic patients. Measurements of salivary F and MLT may help to elucidate not only the circadian rhythms of these hormones under normal and pathological conditions but it may also provide insight in physiology and pathology of the circadian system in general. (author)

  10. Motive of Madenss in Schulz’s Short Stories. A Psychological-Literary Study

    Directory of Open Access Journals (Sweden)

    Barbara Sienkiewicz

    2013-01-01

    Full Text Available Representation of various modes, forms, symptoms and degrees of mental illnesses, frequent in The Street of Crocodiles, are analysed in two perspectives: psychological and literary-cultural. Using the tools of modern psychology, the article interprets the pathological symptoms of Touya, Maria, aunt Agatha, and various other characters, most importantly the advancing illness of father Joseph, who displays symptoms of schizophrenia. Schulz uses a language filled with metaphors, blurring the border between symptoms of illness and metaphors, between the imaginary and the real, and between health and illness, norm and pathology, between the human and the animal. Schulz’s representation of madness opposes the modern understanding, which is dominated by analytical, rationalist identification of an illness, related to a socially determined norm of mental health. It brings back the premodern quality to madness, which becomes a divine phenomenon, related to the pagan rite of fertility, to the “orgy of life” and Dionysian element, and to Freudian life drive. Dionysius and Freud meet in an area independent from the rules of culture and reason: the return to nature, including the nature in a human being. Here, madness becomes a “basic figure” and “the ultimate ur-schema”, as they belong to the unintellectual, basic, ecstatic sphere. This is related to the imperative of penetration of areas that threaten the “balance of the soul”, to address the topic that shows “the scar of removal”, and forces us to ask the question of limits of humanity.

  11. Influence of a Vented Mouthguard on Physiological Responses in Handball.

    Science.gov (United States)

    Schulze, Antina; Laessing, Johannes; Kwast, Stefan; Busse, Martin

    2018-05-23

    Schulze, A, Laessing, J, Kwast, S, and Busse, M. Influence of a vented mouthguard on physiological responses in handball. J Strength Cond Res XX(X): 000-000, 2018-Mouthguards (MGs) improve sports safety. However, airway obstruction and a resulting decrease in performance are theoretical disadvantages regarding their use. The study aim was to assess possible limitations of a "vented" MG on aerobic performance in handball. The physiological effects were investigated in 14 male professional players in a newly developed handball-specific course. The measured values were oxygen uptake, ventilation, heart rate, and lactate. Similar oxygen uptake (V[Combining Dot Above]O2) values were observed with and without MG use (51.9 ± 6.4 L·min·kg vs. 52.1 ± 10.9 L·min·kg). During maximum load, ventilation was markedly lower with the vented MG (153.1 ± 25 L·min vs. 166.3 ± 20.8 L·min). The endexpiratory concentrations of O2 (17.2 ± 0.5% vs. 17.6 ± 0.8%) and CO2 (4.0 ± 0.5% vs. 3.7 ± 0.6%) were significantly lower and higher, respectively, when using the MG. The inspiration and expiration times with and without the MG were 0.6 ± 0.1 seconds vs. 0.6 ± 0.1 seconds and 0.7 ± 0.2 seconds vs. 0.6 ± 0.2 seconds (all not significant), respectively, indicating that there was no relevant airflow restriction. The maximum load was not significantly affected by the MG. The lower ventilation for given V[Combining Dot Above]O2 values associated with MG use may be an effect of improved biomechanics and lower respiratory drive of the peripheral musculature.

  12. The role of otolith size in hearing – Insights from cichlid fishes

    Directory of Open Access Journals (Sweden)

    Tanja Schulz-Mirbach

    2015-10-01

    Full Text Available Otolithic end organs in fishes function as accelerometers and are involved in the senses of balance and hearing (e.g. Popper et al. 2005. Otolith mass and shape are likely decisive factors influencing otolith motion, but while it is largely unknown how different shapes affect otolith movement relative to the sensory epithelium (Popper et al. 2005, greater otolith mass is predicted to result in enhanced stimulation of sensory hair cells and improved hearing (Lychakov and Rebane 2005. What few studies exist on this topic, however, yielded contradicting results in that they did or did not find a correlation between increased otolith mass and enhanced hearing (see Kéver et al. 2014. We investigated the relationship between otolith morphology (including 3D-models of otoliths based on high-resolution microCT imaging and otolith weight and hearing abilities in cichlids while comparing three species (Etroplus maculatus, Hemichromis guttatus, Steatocranus tinanti with different swimbladder morphology and hearing abilities (Schulz-Mirbach et al. 2014. We predicted Etroplus maculatus—the species that displays the best hearing sensitivities—to possess larger/heavier otoliths. As swimbladder extensions in this species are connected to the lagena, we further predicted to find heavier lagenar otoliths. Compared to H. guttatus and S. tinanti, E. maculatus showed the heaviest saccular otoliths, while lagenar otoliths were significantly thinner and lighter than in the former two species, apparently contradicting the hypothesis that the lagena and its otolith are primarily involved in improved hearing abilities. Our results support the idea that there is no ‘simple’ relationship between otolith weight, ancilliary auditory structures and hearing abilities. 3D-models of inner ears and otoliths may be ideally suited for future studies modeling complex otolith motion and thus, may provide a better understanding of how otolith morphology contributes to inner

  13. Understanding how race/ethnicity and gender define age-trajectories of disability: an intersectionality approach.

    Science.gov (United States)

    Warner, David F; Brown, Tyson H

    2011-04-01

    A number of studies have demonstrated wide disparities in health among racial/ethnic groups and by gender, yet few have examined how race/ethnicity and gender intersect or combine to affect the health of older adults. The tendency of prior research to treat race/ethnicity and gender separately has potentially obscured important differences in how health is produced and maintained, undermining efforts to eliminate health disparities. The current study extends previous research by taking an intersectionality approach (Mullings & Schulz, 2006), grounded in life course theory, conceptualizing and modeling trajectories of functional limitations as dynamic life course processes that are jointly and simultaneously defined by race/ethnicity and gender. Data from the nationally representative 1994-2006 US Health and Retirement Study and growth curve models are utilized to examine racial/ethnic/gender differences in intra-individual change in functional limitations among White, Black and Mexican American Men and Women, and the extent to which differences in life course capital account for group disparities in initial health status and rates of change with age. Results support an intersectionality approach, with all demographic groups exhibiting worse functional limitation trajectories than White Men. Whereas White Men had the lowest disability levels at baseline, White Women and racial/ethnic minority Men had intermediate disability levels and Black and Hispanic Women had the highest disability levels. These health disparities remained stable with age-except among Black Women who experience a trajectory of accelerated disablement. Dissimilar early life social origins, adult socioeconomic status, marital status, and health behaviors explain the racial/ethnic disparities in functional limitations among Men but only partially explain the disparities among Women. Net of controls for life course capital, Women of all racial/ethnic groups have higher levels of functional

  14. Morphometric Study on Male Specimens of Hyalomma Anatolicum (Acari: Ixodidae in West of Iran

    Directory of Open Access Journals (Sweden)

    M Abdigoudarzi

    2011-12-01

    Full Text Available Background: Hyalomma anatolicum is the well-known hard tick, which is one of the most important livestock and hu­man pathogens vector, wide range in host and distributed in all over the Hyalomma geographic fauna as well as in Iran. Taxonomy of the Hyalomma ssp. is debatable whereas their identification is a problematic work. The reasons for this claim is time consuming Delpy’s researches in Iran also Schulze School, Feldman-Muhsam and the Russian tick workers. We would like to understand morphometric variation in the field collected H. anatolicum in Iran also validat­ing some morphologic quantitative and qualitative characters.Methods: A total 247 field-collected tick specimens from different geographical regions in west of Iran includes Khuzestan and Lorestan Provinces were studied. The morphologic characters of the ticks were measured by the cali­brated stereomicroscope ‎armed scaled lens. The measurements were analyzed using SPSS ‎for windows, version 16 on an IBM PC, ‎so varied shapes of species in different geographic ‎regions were drawn by the ‎aid of a drawing tube con­nected to a light stereomicroscope.‎Results: One way ANOVA test revealed significant differences among the quantitative parameters in five zones (P<‎‎ 0.‎‎00‎‎1‎ also each zone to other zone by Post Hoc Tests e.g. LSD. No significant differences in the lateral grooves length/conscutum length ratio parameter were found.Conclusion: Morphometric variation in Hyalomma spp is poorly studied. The variation in range and quantity of the mor­phometric parameters of H.anatolicum ‎underlies that the correct recognition and key construction for Hyalomma spe­cies dependes ‎on a complement morphometric study on the other species.

  15. SU-F-E-07: Web-Based Training for Radiosurgery: Methods and Metrics for Global Reach

    International Nuclear Information System (INIS)

    Schulz, R; Thomas, E; Popple, R; Fiveash, J; Jacobsen, E

    2016-01-01

    participation to pre-registration ratio. R.A. Schulz is an employee of Varian Medical Systems

  16. Effects of a helium/oxygen mixture on individuals’ lung function and metabolic cost during submaximal exercise for participants with obstructive lung diseases

    Directory of Open Access Journals (Sweden)

    Häussermann S

    2015-09-01

    Full Text Available Sabine Häussermann,1 Anja Schulze,1 Ira M Katz,2,3 Andrew R Martin,4 Christiane Herpich,1 Theresa Hunger,1 Joëlle Texereau2 1Inamed GmbH, Gauting, Germany; 2Medical R&D, Air Liquide Santé International, Centre de Recherche Paris-Saclay, Les Loges-en-Josas, France; 3Department of Mechanical Engineering, Lafayette College, Easton, PA, USA; 4Department of Mechanical Engineering, University of Alberta, Edmonton, AB, CanadaBackground: Helium/oxygen therapies have been studied as a means to reduce the symptoms of obstructive lung diseases with inconclusive results in clinical trials. To better understand this variability in results, an exploratory physiological study was performed comparing the effects of helium/oxygen mixture (78%/22% to that of medical air.Methods: The gas mixtures were administered to healthy, asthmatic, and chronic obstructive pulmonary disease (COPD participants, both moderate and severe (6 participants in each disease group, a total of 30; at rest and during submaximal cycling exercise with equivalent work rates. Measurements of ventilatory parameters, forced spirometry, and ergospirometry were obtained.Results: There was no statistical difference in ventilatory and cardiac responses to breathing helium/oxygen during submaximal exercise. For asthmatics, but not for the COPD participants, there was a statistically significant benefit in reduced metabolic cost, determined through measurement of oxygen uptake, for the same exercise work rate. However, the individual data show that there were a mixture of responders and nonresponders to helium/oxygen in all of the groups.Conclusion: The inconsistent response to helium/oxygen between individuals is perhaps the key drawback to the more effective and widespread use of helium/oxygen to increase exercise capacity and for other therapeutic applications. Keywords: helium/oxygen, inspiratory capacity, oxygen uptake, COPD, asthma, obstructive airway diseases, exercise, heliox

  17. SU-F-E-07: Web-Based Training for Radiosurgery: Methods and Metrics for Global Reach

    Energy Technology Data Exchange (ETDEWEB)

    Schulz, R [Varian Medical Systems, Palo Alto, CA (United States); Thomas, E [University of Alabama - Birmingham, Birmingham, AL (United States); Popple, R [The University of Alabama at Birmingham, Birmingham, AL (United States); Fiveash, J [University Alabama Birmingham, Birmingham, AL (United States); Jacobsen, E [Univesity of California, Los Angeles, Los Angeles, CA (United States)

    2016-06-15

    participation to pre-registration ratio. R.A. Schulz is an employee of Varian Medical Systems.

  18. Job Crafting: Older Workers’ Mechanism for Maintaining Person-Job Fit

    Directory of Open Access Journals (Sweden)

    Carol M. Wong

    2017-09-01

    Full Text Available Aging at work is a dynamic process. As individuals age, their motives, abilities and values change as suggested by life-span development theories (Lang and Carstensen, 2002; Kanfer and Ackerman, 2004. Their growth and extrinsic motives weaken while intrinsic motives increase (Kooij et al., 2011, which may result in workers investing their resources in different areas accordingly. However, there is significant individual variability in aging trajectories (Hedge et al., 2006. In addition, the changing nature of work, the evolving job demands, as well as the available opportunities at work may no longer be suitable for older workers, increasing the likelihood of person-job misfit. The potential misfit may, in turn, impact how older workers perceive themselves on the job, which leads to conflicting work identities. With the traditional job redesign approach being a top-down process, it is often difficult for organizations to take individual needs and skills into consideration and tailor jobs for every employee (Berg et al., 2010. Therefore, job crafting, being an individualized process initiated by employees themselves, can be a particularly valuable mechanism for older workers to realign and enhance their demands-abilities and needs-supplies fit. Through job crafting, employees can exert personal agency and make changes to the task, social and cognitive aspects of their jobs with the goal of improving their work experience (Wrzesniewski and Dutton, 2001. Building on the Life Span Theory of Control (Heckhausen and Schulz, 1995, we posit that job crafting, particularly cognitive crafting, will be of increasing value as employees age. Through reframing how they think of their job and choosing to emphasize job features that are personally meaningful, older workers can optimize their resources to proactively redesign their jobs and maintain congruent, positive work identities.

  19. First-principles simulation of Raman spectra and structural properties of quartz up to 5 GPa

    International Nuclear Information System (INIS)

    Liu Lei; Lv Chao-Jia; Yi Li; Liu Hong; Du Jian-Guo; Zhuang Chun-Qiang

    2015-01-01

    The crystal structure and Raman spectra of quartz are calculated by using first-principles method in a pressure range from 0 to 5 GPa. The results show that the lattice constants (a, c, and V) decrease with increasing pressure and the a-axis is more compressible than the c axis. The Si–O bond distance decreases with increasing pressure, which is in contrast to experimental results reported by Hazen et al. [Hazen R M, Finger L W, Hemley R J and Mao H K 1989 Solid State Communications 725 507–511], and Glinnemann et al. [Glinnemann J, King H E Jr, Schulz H, Hahn T, La Placa S J and Dacol F 1992 Z. Kristallogr. 198 177–212]. The most striking changes are of inter-tetrahedral O–O distances and Si–O–Si angles. The volume of the tetrahedron decreased by 0.9% (from 0 to 5 GPa), which suggests that it is relatively rigid. Vibrational models of the quartz modes are identified by visualizing the associated atomic motions. Raman vibrations are mainly controlled by the deformation of the tetrahedron and the changes in the Si–O–Si bonds. Vibrational directions and intensities of atoms in all Raman modes just show little deviations when pressure increases from 0 to 5 GPa. The pressure derivatives (dν i /dP) of the 12 Raman frequencies are obtained at 0 GPa–5 GPa. The calculated results show that first-principles methods can well describe the high-pressure structural properties and Raman spectra of quartz. The combination of first-principles simulations of the Raman frequencies of minerals and Raman spectroscopy experiments is a useful tool for exploring the stress conditions within the Earth. (paper)

  20. Evaluation of a Mobile Phone-Based Intervention to Increase Parents' Knowledge About the Measles-Mumps-Rubella Vaccination and Their Psychological Empowerment: Mixed-Method Approach.

    Science.gov (United States)

    Fadda, Marta; Galimberti, Elisa; Fiordelli, Maddalena; Schulz, Peter Johannes

    2018-03-07

    There is mixed evidence on the effectiveness of vaccination-related interventions. A major limitation of most intervention studies is that they do not apply randomized controlled trials (RCTs), the method that, over the last 2 decades, has increasingly been considered as the only method to provide proof of the effectiveness of an intervention and, consequently, as the most important instrument in deciding whether to adopt an intervention or not. This study, however, holds that methods other than RCTs also can produce meaningful results. The aim of this study was to evaluate 2 mobile phone-based interventions aimed at increasing parents' knowledge of the measles-mumps-rubella (MMR) vaccination (through elements of gamification) and their psychological empowerment (through the use of narratives), respectively. The 2 interventions were part of an RCT. We conducted 2 studies with the RCT participants: a Web-based survey aimed at assessing their rating of the tool regarding a number of qualities such as usability and usefulness (N=140), and qualitative telephonic interviews to explore participants' experiences with the app (N=60). The results of the survey showed that participants receiving the knowledge intervention (alone or together with the empowerment intervention) liked the app significantly better compared with the group that only received the empowerment intervention (F 2,137 =15.335; Pbenefits of the vaccination at the same time. International Standard Randomized Controlled Trial Number 30768813; http://www.isrctn.com/ ISRCTN30768813 (Archived by WebCite at http://www.webcitation.org/6xOQSJ3w8). ©Marta Fadda, Elisa Galimberti, Maddalena Fiordelli, Peter Johannes Schulz. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 07.03.2018.

  1. Insights into location dependent loss-of-coolant-accident (LOCA) frequency assessment for GSI-191 risk-informed applications

    Energy Technology Data Exchange (ETDEWEB)

    Fleming, K.N., E-mail: KarlFleming@comcast.net [KNF Consulting LLC, Spokane, WA (United States); Lydell, B.O.Y. [SIGMA-PHASE INC., Vail, AZ (United States)

    2016-08-15

    Highlights: • Role of operating experience in loss-of-coolant-accident (LOCA) frequency assessment. • Plant-to-plant variability in calculated LOCA frequency. • Frequency of double-ended-guillotine-break (DEGB). • Uncertainties in LOCA frequencies. • Risk management insights. - Abstract: As a tribute to the published work by S.H. Bush, S. Beliczey and H. Schulz, this paper assesses the progress with methods and techniques for quantifying the reliability of piping systems in commercial nuclear power plants on the basis of failure rate estimates derived from field experience data in combination with insights and results from probabilistic fracture mechanics analyses and expert elicitation exercises. This status assessment is made from a technical perspective obtained through development of location-specific loss-of-coolant-accident (LOCA) frequencies for input to risk-informed resolution of the generic safety issue (GSI) 191. The methods and techniques on which these GSI-191 applications are based build on a body of work developed by the authors during a period spanning more than two decades. The insights that are presented and discussed in this paper cover today’s knowledge base concerning how to utilize a risk-informed approach to the assessment of piping reliability in the context of probabilistic risk assessment (PRA) in general and the resolution of GSI-191 in particular. Specifically the paper addresses the extent to which LOCA frequencies vary from location to location within a reactor coolant system pressure boundary (RCPB) for a given plant as well as vary from plant to plant, and the reasons for these variabilities. Furthermore, the paper provides the authors’ perspectives on interpretations and applications of information extracted from an expert elicitation process to obtain LOCA frequencies as documented in NUREG-1829 and how to apply this information to GSI-191. Finally, this paper documents technical insights relative to mitigation of

  2. Impact of super-distal ash fallout on tropical hydrology and landscape: a case study from the YTT deposits of the Perak river, Malaysia

    Science.gov (United States)

    Gatti, E.; Saidin, M.; Gibbard, P.; Oppenheimer, C.

    2011-12-01

    The Younger Toba Tuff eruption, approximately 73 ka ago, is the largest known for the Quaternary and its climate, environmental and human consequences are keenly debated (Oppenheimer, 2011).While the distribution (Rose and Chesner, 1987; Rose and Chesner, 1990; Chesner et al., 1991; Schulz et al., 2002; Von Rad et al., 2002) , geochemical properties (Shane et al., 1995; Westgate et al., 1998) and volcanic significance (Rampino and Self, 1982; Rampino and Self, 1993; Rampino and Ambrose, 2000; Oppenheimer, 2002; Mason et al., 2004)of the YTT have been widely studied, few attention has been given to the significance of the distal volcanic ash deposits within their receiving basin context. Although several studies exist on the impact of pyroclastic flows on proximal rivers and lakes (Collins and Dunne, 1986; Thompson et al., 1986; Hayes et al., 2002; Németh and Cronin, 2007), only few address the issues of the dynamic of preservation of super-distal fine ash deposits in rivers (also due to the lack of direct data on super-eruptions). It has also been demonstrated that models of the styles and timing of distal volcanoclastic re-sedimentation are more complicated than those developed for proximal settings of stratovolcanoes (Kataoka et al., 2009). We present an analysis of the taphonomy (intended as accumulation and preservation) of distal volcanic ash in fluvial and lacustrian contexts in newly discovered Toungest Toba Tuff sites in the Lenggong valley, western Peninsular Malaysia. The paper aims to characterise the nature of distal tephras in fluvial environments towards a stratigraphic distinction between primary ash and secondary ash, characterisation of the pre-ash fall receiving environment in term of fluvial dynamic and landscape morphology, and assessment of the time of recovery.

  3. On adiabatic pair potentials of highly charged colloid particles

    Science.gov (United States)

    Sogami, Ikuo S.

    2018-03-01

    Generalizing the Debye-Hückel formalism, we develop a new mean field theory for adiabatic pair potentials of highly charged particles in colloid dispersions. The unoccupied volume and the osmotic pressure are the key concepts to describe the chemical and thermodynamical equilibrium of the gas of small ions in the outside region of all of the colloid particles. To define the proper thermodynamic quantities, it is postulated to take an ensemble averaging with respect to the particle configurations in the integrals for their densities consisting of the electric potential satisfying a set of equations that are derived by linearizing the Poisson-Boltzmann equation. With the Fourier integral representation of the electric potential, we calculate first the internal electric energy of the system from which the Helmholtz free energy is obtained through the Legendre transformation. Then, the Gibbs free energy is calculated using both ways of the Legendre transformation with respect to the unoccupied volume and the summation of chemical potentials. The thermodynamic functions provide three types of pair potentials, all of which are inversely proportional to the fraction of the unoccupied volume. At the limit when the fraction factor reduces to unity, the Helmholtz pair potential turns exactly into the well known Derjaguin-Landau-Verwey-Overbeek repulsive potential. The Gibbs pair potential possessing a medium-range strong repulsive part and a long-range weak attractive tail can explain the Schulze-Hardy rule for coagulation in combination with the van der Waals-London potential and describes a rich variety of phenomena of phase transitions observed in the dilute dispersions of highly charged particles.

  4. Development of ceftazidime resistance in an acute Burkholderia pseudomallei infection

    Directory of Open Access Journals (Sweden)

    Sarovich DS

    2012-08-01

    Full Text Available Derek S Sarovich,1,2,* Erin P Price,1,2,* Direk Limmathurotsakul,3 James M Cook,1 Alex T Von Schulze,1 Spenser R Wolken,1 Paul Keim,1 Sharon J Peacock,3,4 Talima Pearson1 1Center for Microbial Genetics and Genomics, Northern Arizona University, Flagstaff, AZ, USA; 2Tropical and Emerging Infectious Diseases Division, Menzies School of Health Research, Darwin, Australia; 3Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand; 4Department of Medicine, University of Cambridge, Cambridge, United Kingdom*These authors contributed equally to this workAbstract: Burkholderia pseudomallei, a bacterium that causes the disease melioidosis, is intrinsically resistant to many antibiotics. First-line antibiotic therapy for treating melioidosis is usually the synthetic β-lactam, ceftazidime (CAZ, as almost all B. pseudomallei strains are susceptible to this drug. However, acquired CAZ resistance can develop in vivo during treatment with CAZ, which can lead to mortality if therapy is not switched to a different drug in a timely manner. Serial B. pseudomallei isolates obtained from an acute Thai melioidosis patient infected by a CAZ susceptible strain, who ultimately succumbed to infection despite being on CAZ therapy for the duration of their infection, were analyzed. Isolates that developed CAZ resistance due to a proline to serine change at position 167 in the β-lactamase PenA were identified. Importantly, these CAZ resistant isolates remained sensitive to the alternative melioidosis treatments; namely, amoxicillin-clavulanate, imipenem, and meropenem. Lastly, real-time polymerase chain reaction-based assays capable of rapidly identifying CAZ resistance in B. pseudomallei isolates at the position 167 mutation site were developed. The ability to rapidly identify the emergence of CAZ resistant B. pseudomallei populations in melioidosis patients will allow timely alterations in treatment strategies

  5. Evaluation of Skid Resistance of Wearing Course Made Of Stone Mastic Asphalt Mixture in Laboratory Conditions

    Science.gov (United States)

    Wasilewska, Marta

    2017-10-01

    This paper presents the comparison of skid resistance of wearing course made of SMA (Stone Mastic Asphalt) mixtures which differ in resistance to polishing of coarse aggregate. Dolomite, limestone, granite and trachybasalt were taken for investigation. SMA mixtures have the same nominal size of aggregate (11 mm) and very similar aggregate particle-size distribution in mineral mixtures. Tested SMA11 mixtures were designed according to EN 13108-5 and Polish National Specification WT-2: 2014. Evaluation of the skid resistance has been performed using the FAP (Friction After Polishing) test equipment also known as the Wehner/Schulze machine. Laboratory method enables to compare the skid resistance of different types of mixtures under specified conditions simulating polishing processes. Tests were performed on both the specimens made of each coarse aggregate and SMA11 mixtures containing these aggregates. Measuring of friction coefficient μm was conducted before and during polishing process up to 180 0000 passes of polishing head. Comparison of the results showed differences in sensitivity to polishing among particular mixtures which depend on the petrographic properties of rock used to produce aggregate. Limestone and dolomite tend to have a fairly uniform texture with low hardness which makes these rock types susceptible to rapid polishing. This caused lower coefficient of friction for SMA11 mixtures with limestone and dolomite in comparison with other test mixtures. These significant differences were already registered at the beginning of the polishing process. Limestone aggregate had lower value of μm before starting the process than trachybasalt and granite aggregate after its completion. Despite the differences in structure and mineralogical composition between the granite and trachybasalt, slightly different values of the friction coefficient at the end of polishing were obtained. Images of the surface were taken with the optical microscope for better

  6. SIGNIFICADOS DE LA PALABRA "ESPARCIMIENTO" PARA ESTUDIANTES DE LA UNIVERSIDAD DE COSTA RICA Y DE MONTCLAIR STATE UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Susana Juniu

    2010-01-01

    Full Text Available El esparcimiento y la recreación frecuentemente se definen de manera individual y, por lo tanto, no se entienden o interpretan universalmente. Los diferentes contextos culturales pueden originar distintas definiciones o significados de esparcimiento. El reto de las personas que estudian el esparcimiento es interpretarlo de tal forma que ayude a las personas a entender acerca de su valor en la calidad de vida. Por consiguiente, este estudio examinó el significado de esparcimiento para estudiantes de un curso de estudios generales de la Universidad de Costa Rica (UCR y de Montclair State University (MSU, una universidad estatal del noreste de Estados Unidos, en el I ciclo lectivo del 2009. Las personas participantes fueron 388 estudiantes (149 hombres y 240 mujeres, promedio edad = 21 años, DE = 3.3 del curso de Actividad Deportiva, de carreras de grado de ambas universidades. El estudiantado contestó el Inventario de Significados de Esparcimiento (Schulz y Watkins, 2007. Este cuestionario incluye cuatro categorías: pasar el tiempo, escapar de presiones, tomar decisiones y lograr autorrealización. En términos generales, las diferencias estadísticamente significativas entre los grupos universitarios se relacionaron con el concepto de esparcimiento como "pasar el tiempo" y "tomar decisiones". Las percepciones de esparcimiento como "escapar de presiones" y "lograr autorrealización" sólo fueron el resultado de diferencias estadísticas significativas de casos específicos. Los resultados indican que los estudiantes de MSU tienden más a percibir esparcimiento como "pasar el tiempo" y "tomar decisiones" que la contraparte costarricense.

  7. Quantitative analysis of textures produced in a hot-extruded zirconium plate

    International Nuclear Information System (INIS)

    Couterne, J.

    1967-01-01

    The textures produced in zirconium by the extrusion at 730 deg C of a cylindrical billet in the form of a plate having a rectangular cross-section, have been studied by the Schulz method using an isotropic standard. These textures have been determined both parallel to the plane of the plate and parallel to the plane of the sides, All the results are analyzed in a final discussion which makes it possible to show, in particular near the edges of the plate, that certain components of the textures observed in the two series of recordings are in fact aspects of the same texture seen from two different angles, It is shown furthermore that the zirconium thus shaped has cold-work textures and als recrystallisation textures formed after the preceding cold-working, If the observed textures are considered schematically, it can be see that two of these have already been described in the literature and are similar to those found in rolled products: these textures are such that the (0001) planes are inclined at 36 deg C and 60 deg C respectively with respect to a plan tangential to the curve (envelope of transverse flow rates) resulting from the extrusion geometry under consideration; the third texture is defined. by the fact that the (0001) plane is orthogonal to the exterior surfaces of the plate. The direction of extrusion associated with these planes and common to the three textures is of the type , Dilatometric tests have been carried out on samples taken both parallel and perpendicular to the extrusion direction, These tests show that the zirconium is dilatometrically anisotropic and that a plot of (α v )-a against temperature shows a change of gradient at 400 deg C, this latter effect may be due to the change in the electronic configuration of the metal occurring at this temperature. (author) [fr

  8. Internet Video Telephony Allows Speech Reading by Deaf Individuals and Improves Speech Perception by Cochlear Implant Users

    Science.gov (United States)

    Mantokoudis, Georgios; Dähler, Claudia; Dubach, Patrick; Kompis, Martin; Caversaccio, Marco D.; Senn, Pascal

    2013-01-01

    Objective To analyze speech reading through Internet video calls by profoundly hearing-impaired individuals and cochlear implant (CI) users. Methods Speech reading skills of 14 deaf adults and 21 CI users were assessed using the Hochmair Schulz Moser (HSM) sentence test. We presented video simulations using different video resolutions (1280×720, 640×480, 320×240, 160×120 px), frame rates (30, 20, 10, 7, 5 frames per second (fps)), speech velocities (three different speakers), webcameras (Logitech Pro9000, C600 and C500) and image/sound delays (0–500 ms). All video simulations were presented with and without sound and in two screen sizes. Additionally, scores for live Skype™ video connection and live face-to-face communication were assessed. Results Higher frame rate (>7 fps), higher camera resolution (>640×480 px) and shorter picture/sound delay (<100 ms) were associated with increased speech perception scores. Scores were strongly dependent on the speaker but were not influenced by physical properties of the camera optics or the full screen mode. There is a significant median gain of +8.5%pts (p = 0.009) in speech perception for all 21 CI-users if visual cues are additionally shown. CI users with poor open set speech perception scores (n = 11) showed the greatest benefit under combined audio-visual presentation (median speech perception +11.8%pts, p = 0.032). Conclusion Webcameras have the potential to improve telecommunication of hearing-impaired individuals. PMID:23359119

  9. Biogas upgrading to biomethane. Proceedings; Biogasaufbereitung zu Biomethan. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-12-05

    Within the 6th Hanauer Dialogue 'Biogas upgrading to biomethane' at 21st February, 2008, the following lectures were held: (a) Processing of biogas - an introduction (Michael Beil); (b) The climate protecting targets of the Federal Republic of Germany: Which role will play the upgrading of biogas, and which legal boundary conditions are created by the Federal Government? (Uwe Holzhammer); (c) Future strategy: CH{sub 4} grids (Juergen Schmid); (d) Biogas upgrading and biomethane utilization in Sweden (Anneli Petersson); (e) Biogas upgrading and utilization of bio methane in Switzerland (Arthur Wellinger); (f) Biogas upgrading by means of pressure swing adsorption (Alfons Schulte-Schulze Berndt); (g) Biogas upgrading by means of pressurized water washing (Ulf Richter); (h) Biogas upgrading for feeding in public grids. The case of biogas plant Bruck a.d. Leitha (Michael Harasek); (i) Biogas upgrading by means of chemical absorption according to the LP Cooab process (Jerome van Beek); (j) Practical experiences in unpressurized amine washing MT bio methane (Karsten Wuensche); (k) Biogas upgrading by means of organic physical washing with HAASE biogas amplifiers (Roland Kahn); (l) Upgrading using cryogenic technology; the GPP registered -system (Jeroen de Pater); (m) Micro Gas Distribution Systems: Alternatives to biogas upgrading and grid injection (Michael Beil, Bernd Krautkremer); (n) Feeding of exchange gas. The case of project Straelen and Kerpen (Frank Schaefer); (o) Feeding of biogas from the view of grid operators (Norbert Nordmeyer); BIOGASMAX: Biogas as Vehicle Fuel - Market Expansion to 2020 Air Quality (Michael Beil, Uwe Hoffstede); (p) Study: Feeding of biogas into the natural gas distribution system (Fachagentur Nachwachsende Rohstoffe).

  10. Quality of life and social support in patients with multiple sclerosis.

    Science.gov (United States)

    Rosiak, Katarzyna; Zagożdżon, Paweł

    2017-10-29

    Quality of life and needforsocial support in persons diagnosed with multiple sclerosis (MS) are to a large extent determined by the degree of their disability. The aim of the study was to analyze an association between specific forms of MS, subjectively perceived quality of life and social support. The study included subjects with established diagnosis of MS, treated at rehabilitation centers, hospitals and in a home setting, as well as the members of patient organizations. After being informed about objectives of the study, type of included tasks and way to complete them, each participant was handed out a set of questionnaires: Berlin Social Support Scales (Łuszczyńska, Kowalska, Schwarzer, Schulz), Quality of Life Questionnaire (WHOQOLBREF), as well as a survey developed specifically for the purposes of this project. The results were subjected to statistical analysis with STATA 12 package. The study included a total of 110 persons (67 women and 43 men). Quality of life overall, as well in physical, psychological, social relationships and environmental health domains, turned out to be particularly important in patients with primary-progressive MS. Irrespective of MS type, social support overall did not play a significant role on univariate analysis. However, subgroup analysis according to sex demonstrated that men with MS received social support four times less often than women. Quality of life in individuals with primary-progressive MS is significantly lower than in patients presenting with other types of this disease. Men with MS are more likely to present with worse scores for social support overall. They are less likely both to acknowledge the need for support and to realize the availability of support they actually need.

  11. Multicentric osteolysis with nodulosis, arthritis, and cardiac defect syndrome: loss of MMP2 leads to increased apoptosis with alteration of apoptotic regulators and caspases and embryonic lethality

    Directory of Open Access Journals (Sweden)

    Mosig RA

    2014-11-01

    Full Text Available Rebecca A Mosig,1 Richard Schulz,2,3 Zamaneh Kassiri,4 Mitchell B Schaffler,5 John A Martignetti1 1Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Department of Pharmacology; 3Department of Pediatrics, 4Department of Physiology, Cardiovascular Research Centre, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, AB, Canada; 5Department of Biomedical Engineering, City College of New York, New York, NY, USA Abstract: Inactivating mutations of matrix metalloproteinase 2 (MMP2 cause multicentric osteolysis with nodulosis and arthritis, one of a group of inherited osteolytic and arthritic disorders. We have previously shown that mice lacking Mmp2 share similar syndromic features with the human disorder, and at the cellular level, Mmp2-/- mouse osteoblasts and osteoclasts have reduced numbers and proliferation rates at critical developmental time points. While previously hypothesized, the effect of MMP2 loss on apoptosis has not been examined in this system. We therefore sought to clarify its role in mediating the developmental defects in Mmp2-/- mice using immunohistochemistry, immunoblot analysis, and quantitative reverse transcription polymerase chain reaction analysis. We also explored the effects of MMP2 inhibition in the osteogenic sarcoma cell line SaOS2. Loss of MMP2 resulted in increased apoptosis and caspase activation both in vitro and in vivo. MMP2-deficient cells had increased Fas expression and reduced levels of the key survival signals p-FAK, p-ERK, cFLIP, and Bcl-2. Notably, and in marked contrast to their original characterization, there was a significant increase in the in utero demise of homozygous Mmp2-/- embryos. Specifically, litters from heterozygous crosses consistently yielded nearly 85% fewer than expected homozygous Mmp2-/- pups. Taken together, our findings highlight a new role for MMP2 in preventing apoptosis during development and growth. Keywords

  12. Perampanel in the management of partial-onset seizures: a review of safety, efficacy, and patient acceptability

    Directory of Open Access Journals (Sweden)

    Schulze-Bonhage A

    2015-08-01

    Full Text Available Andreas Schulze-Bonhage, Mandy Hintz Epilepsy Center, University Medical Center Freiburg, Freiburg, Germany Abstract: Perampanel (PER is a novel antiepileptic drug recently introduced for the adjunctive treatment in epilepsy patients aged 12 years or older with partial-onset seizures with or without secondary generalization in the US and Europe. Its antiepileptic action is based on noncompetitive inhibition of postsynaptic AMPA receptors, decreasing excitatory synaptic transmission. Evaluation of efficacy in three placebo-controlled randomized Phase III studies showed that add-on therapy of PER decreased seizure frequencies significantly compared to placebo at daily doses between 4 mg/day and 12 mg/day. PER’s long half-life of 105 hours allows for once-daily dosing that is favorable for patient compliance with intake. Long-term extension studies showed a 62.5%–69.6% adherence of patients after 1 year of treatment, comparing favorably with other second-generation antiepileptic drugs. Whereas these trials demonstrated an overall favorable tolerability profile of PER, nonspecific central nervous system adverse effects like somnolence, dizziness, headache, and fatigue may occur. In addition, neuropsychiatric disturbances ranging from irritability to suicidality were reported in several case reports; both placebo-controlled and prospective long-term extension trials showed a low incidence of such behavioral and psychiatric complaints. For early recognition of neuropsychiatric symptoms like depression, anxiety, and aggression, slow titration and close monitoring during drug introduction are mandatory. This allows on the one hand to recognize patients particularly susceptible to adverse effects of the drug, and on the other hand to render the drug’s full potential of seizure control available for the vast majority of patient groups tolerating the drug well. Keywords: epilepsy, antiepileptic drugs, AMPA receptor, structural epilepsy, partial

  13. Sensitivity of tropical rainbelt over Africa and Middle East to dust shortwave absorption: Experiments using a high resolution AGCM

    KAUST Repository

    Bangalath, Hamza Kunhu; Stenchikov, Georgiy L.

    2015-01-01

    Response of the rainbelt over Africa to dust direct radiative forcing has been an area of lively debate and is a subject of ongoing research. Previous modeling studies have contrasting results producing different amplitudes or even signs of responses. Uncertainties in the dust radiative forcing are thought to be the major cause of discrepancies in the simulated responses among various studies. The imaginary part of mineral dust shortwave refractive index, which defines the dust absorptivity, has a wide range of values estimated from various observational and modeling studies, as it depends on dust chemical composition and mineralogy. Balkanski et al. (2007) estimated dust shortwave refractive indices by assuming 3 different hematite contents, 0.9%, 1.5% and 2.7% by volume, which corresponds to inefficient, standard, and very efficient dust shortwave absorption, respectively. To investigate the sensitivity of the position and intensity of the tropical rainbelt over Africa and its extension to the Arabian Peninsula to dust shortwave absorption, we have conducted ensembles of numerical simulations for each of the three dust absorptivity scenarios using a high resolution Atmospheric General Circulation Model (AGCM), GFDL's High Resolution Atmospheric Model (HiRAM), at a spatial resolution of 25 km. We found that the strength and the latitudinal extent of the rainbelt are very sensitive to dust shortwave absorption, as well as circulations at various spatiotemporal scales that drive the climate of the region. Reference: Balkanski, Y., M. Schulz, T. Claquin, and S. Guibert (2007), Reevaluation of mineral aerosol radiative forcings suggests a better agreement with satellite and AERONET data, Atmos. Chem. Phys., 7, 81 - 95.

  14. Development of a computational program for treatment of texture data by the X-ray diffraction technique

    International Nuclear Information System (INIS)

    Galego, Eguiberto

    2004-01-01

    In this work it has been developed a computational program for treatment of texture data by the X-ray diffraction technique using pole figures. It has been applied the resolution method by spherical harmonical series expansion for cubic and hexagonal microscopic symmetry and orthorhombic macroscopic symmetry. For yielding the microscopic symmetries it has been necessary the implementation of algorithmic for calculation the spherical harmonic of specific surface. The generation of Legendre Polynomial, based on the experimental data in relation to a and β step angles, is execution in real time. In the introduction of data, the graphical representation of pole figure is drawn in stereo graphic projection, being possible to the analyst three dimensional (3D) visualization. An internal routine verify validity of the Miller indexes, being possible to analyst the correction. The program exhibit the possible corrections applied to experimental data: defocusing, background and orientation of lamination direction (β angle). The correction of the defocusing and background is the executed automatically based on the optic used in the X-ray equipment (Schulz geometric). It has been implemented a routine of graphic manipulation of the contour iso lines for generation of the orientation distribution function (ODF), with easy manipulation of the number of lines and colors. In the ODF graphic, with the action of the mouse cursor on any section, it is visualized the values of Euler angles (φ 1 , Φ, φ 2 ) and of the respective f(g) intensity. Concomitantly, there is 3D graphic visualization of the crystal position in relation to the rolling direction. There is the possibility of graphic visualization in 3D of any section of the ODF. It is also possible the graphic visualization of the texture fiber. This program was named Texture Analysis Program (TAP). (author)

  15. [Skilled communication as "intervention" : Models for systematic communication in the healthcare system].

    Science.gov (United States)

    Weinert, M; Mayer, H; Zojer, E

    2015-02-01

    Specific communication training is currently not integrated into anesthesiology curricula. At the same time communication is an important key factor when working with colleagues, in the physician-patient relationship, during management of emergencies and in avoiding or reducing the legal consequences of adverse medical events. Therefore, focused attention should be brought to this area. In other high risk industries, specific communication training has been standard for a long time and in medicine there is an approach to teach and train these soft skills by simulation. Systematic communication training, however, is rarely an established component of specialist training. It is impossible not to communicate whereby nonverbal indications, such as gestures, mimic expression, posture and tone play an important part. Miscommunication, however, is common and leads to unproductive behavior. The cause of this is not always obvious. This article provides an overview of the communication models of Shannon, Watzlawick et al. and Schulz von Thun et al. and describes their limitations. The "Process Communication Model®" (PCM) is also introduced. An overview is provided with examples of how this tool can be used to look at the communication process from a systematic point of view. People have different psychological needs. Not taking care of these needs will result in individual stress behavior, which can be graded into first, second and third degrees of severity (driver behavior, mask behavior and desperation). These behavior patterns become exposed in predictable sequences. Furthermore, on the basis of this model, successful communication can be established while unproductive behavior that occurs during stress can be dealt with appropriately. Because of the importance of communication in all areas of medical care, opportunities exist to focus research on the influence of targeted communication on patient outcome, complications and management of emergencies.

  16. Effect of gender on the hearing performance of adult cochlear implant patients.

    Science.gov (United States)

    Lenarz, Minoo; Sönmez, Hasibe; Joseph, Gert; Büchner, Andreas; Lenarz, Thomas

    2012-05-01

    To evaluate the role of gender on the hearing performance of postlingually deafened adult patients with cochlear implants. Individual retrospective cohort study. There were 638 postlingually deafened adults (280 men and 358 women) selected for a retrospective evaluation of their hearing performance with cochlear implants. Both genders underwent the same surgical and rehabilitative procedures and benefited from the latest technological advances available. There was no significant difference in the age, duration of deafness, and preoperative hearing performance between the genders. The test battery was composed of the Freiburger Monosyllabic Test, Speech Tracking, and the Hochmair-Schulz-Moser (HSM) sentence test in quiet and in 10-dB noise. The results of 5 years of follow-up are presented here. Genders showed a similar performance in Freiburger Monosyllabic Test and Speech Tracking Test. However, in the HSM test in noise, men performed slightly better than women in all of the follow-up sessions, which was statistically significant at 2 and 4 years after implantation. Although normal-hearing women use more predictive cognitive strategies in speech comprehension and are supposed to have a more efficient declarative memory system, this may not necessarily lead to a better adaptation to the altered auditory information delivered by a cochlear implant. Our study showed that in more complex listening situations such as speech tests in noise, men tend to perform slightly better than women. Gender may have an influence on the hearing performance of postlingually deafened adults with cochlear implants. Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.

  17. [Here the world is burning: the 70th anniversary of the death of neurologist Dr. John Rittmeister].

    Science.gov (United States)

    Teller, Ch

    2013-09-01

    John Rittmeister was a German neurologist (1898-1943) who was executed in Berlin-Plötzensee because of his decision to support organized political resistance against National Socialism. He grew up in a socially and materially privileged environment and following his final school examinations (Abitur) in 1917 he volunteered for war duties despite limited physical capabilities and was posted as a private to the war front in the Italian Alps and the Champagne district. While he was there he made his first social experiences outside his original surroundings. After the war he studied medicine and following the final state examinations and graduation he progressed to specialist training as a neurologist in Munich. At this time he came into contact with C.G. Jung. During a study period in London in 1929 he worked for several weeks as a resident at Toynbee Hall, a university institution in Whitechapel and experienced the methods of community work used there which were known under the term settlement movement. He continued his specialist activities in the neurological clinic in Zürich founded by C. von Monakow. Following the experiences in London he broke up with C.G. Jung and turned to Sigmund Freud and therapeutic analysis under Gustav Bally. In 1937 he returned to Germany. In 1939 he became director of the Policlinic of the German Institute for Psychological Research and Psychotherapy. Probably also due to his own war experiences in 1941/1942 he participated in the drafting of a flyer for the Schulze-Boysen/Harnack group against the war and after 8 months in prison he was executed in Berlin on 13 May 1943.

  18. New processes for the selective production of 1-octene

    Energy Technology Data Exchange (ETDEWEB)

    van Leeuwen, P.W.N.M.; Clement, N.D.; Tschan, M.J.L. [Institute of Chemical Research Catalonia ICIQ, Tarragona (Spain)

    2011-07-15

    Linear alpha-olefins, especially 1-hexene and 1-octene, are key components for the production of LLDPE and the demand for 1-hexene and 1-octene increased enormously in recent years. Here we review the new processes for 1-octene production based on homogeneous catalysts. Sasol's coal-based high temperature Fischer-Tropsch technology produces an Anderson-Schulz-Flory distribution of hydrocarbons with high alpha-olefin content and the desired alkenes, including 1-heptene and 1-octene, are separated by distillation. In this case, as in the SHOP process, 1-octene constitutes only a minor part of the total yield. Nowadays other technologies are being applied or considered for on-purpose 1-octene production: hydroformylation of 1-heptene, the telomerization of 1,3-butadiene, and ethene tetramerization. 1-Heptene can be converted in three steps to 1-octene: (1) hydroformylation of 1-heptene to octanal, (2) hydrogenation of octanal to 1-octanol, and (3) dehydration of 1-octanol to 1-octene. This process was commercialized by Sasol. Dow commercialized a process based on butadiene. Telomerization of butadiene with methanol in the presence of a palladium catalyst yields 1-methoxy-2,7-octadiene, which is fully hydrogenated to 1-methoxyoctane in the next step. Subsequent cracking of 1-methoxyoctane gives 1-octene and methanol for recycle. Recently highly active and stable phosphine based systems were reported that show particularly good performance for the industrially attractive feedstock, the C{sub 4} cut of the paraffin cracker. 1-Hexene can be obtained by ethene trimerization by a family of catalysts based mainly on Cr.

  19. Insights into location dependent loss-of-coolant-accident (LOCA) frequency assessment for GSI-191 risk-informed applications

    International Nuclear Information System (INIS)

    Fleming, K.N.; Lydell, B.O.Y.

    2016-01-01

    Highlights: • Role of operating experience in loss-of-coolant-accident (LOCA) frequency assessment. • Plant-to-plant variability in calculated LOCA frequency. • Frequency of double-ended-guillotine-break (DEGB). • Uncertainties in LOCA frequencies. • Risk management insights. - Abstract: As a tribute to the published work by S.H. Bush, S. Beliczey and H. Schulz, this paper assesses the progress with methods and techniques for quantifying the reliability of piping systems in commercial nuclear power plants on the basis of failure rate estimates derived from field experience data in combination with insights and results from probabilistic fracture mechanics analyses and expert elicitation exercises. This status assessment is made from a technical perspective obtained through development of location-specific loss-of-coolant-accident (LOCA) frequencies for input to risk-informed resolution of the generic safety issue (GSI) 191. The methods and techniques on which these GSI-191 applications are based build on a body of work developed by the authors during a period spanning more than two decades. The insights that are presented and discussed in this paper cover today’s knowledge base concerning how to utilize a risk-informed approach to the assessment of piping reliability in the context of probabilistic risk assessment (PRA) in general and the resolution of GSI-191 in particular. Specifically the paper addresses the extent to which LOCA frequencies vary from location to location within a reactor coolant system pressure boundary (RCPB) for a given plant as well as vary from plant to plant, and the reasons for these variabilities. Furthermore, the paper provides the authors’ perspectives on interpretations and applications of information extracted from an expert elicitation process to obtain LOCA frequencies as documented in NUREG-1829 and how to apply this information to GSI-191. Finally, this paper documents technical insights relative to mitigation of

  20. Meaningful activities for improving the wellbeing of people with dementia: beyond mere pleasure to meeting fundamental psychological needs.

    Science.gov (United States)

    Nyman, Samuel R; Szymczynska, Paulina

    2016-03-01

    Dementia is being increasingly recognised as a major public health issue for our ageing populations. A critical aspect of supporting people with dementia is facilitating their participation in meaningful activities. However, research to date has not drawn on theories of ageing from developmental psychology that would help undergird the importance of such meaningful activity. For the first time, we connect existing activity provision for people with dementia with developmental psychology theories of ageing. We reviewed the literature in two stages: first, we narratively searched the literature to demonstrate the relevance of psychological theories of ageing for provision of meaningful activities for people with dementia, and in particular focused on stage-based theories of adult development (Carl Jung and Erik Erikson), gerotranscendence (Tornstam), selective optimisation with compensation (Baltes and Baltes), and optimisation in primary and secondary control (Heckhausen and Schulz). Second, we systematically searched PubMed and PsycINFO for studies with people with dementia that made use of the aforementioned theories. The narrative review highlights that activity provision for people with dementia goes beyond mere pleasure to meeting fundamental psychological needs. More specifically, that life review therapy and life story work address the need for life review; spiritual/religious activities address the need for death preparation; intergenerational activities address the need for intergenerational relationships; re-acquaintance with previously conducted leisure activities addresses the need for a sense of control and to achieve life goals; and pursuit of new leisure activities addresses the need to be creative. The systematic searches identified two studies that demonstrated the utility of applying Erikson's theory of psychosocial development to dementia care. We argue for the importance of activity provision for people with dementia to help promote wellbeing

  1. Effect of aggregate graining compositions on skid resistance of Exposed Aggregate Concrete pavement

    Science.gov (United States)

    Wasilewska, Marta; Gardziejczyk, Wladysław; Gierasimiuk, Pawel

    2018-05-01

    The paper presents the evaluation of skid resistance of EAC (Exposed Aggregate Concrete) pavements which differ in aggregate graining compositions. The tests were carried out on concrete mixes with a maximum aggregate size of 8 mm. Three types of coarse aggregates were selected depending on their resistance to polishing which was determined on the basis of the PSV (Polished Stone Value). Basalt (PSV 48), gabbro (PSV 50) and trachybasalt (PSV 52) aggregates were chosen. For each type of aggregate three graining compositions were designed, which differed in the content of coarse aggregate > 4mm. Their content for each series was as follows: A - 38%, B - 50% and C - 68%. Evaluation of the skid resistance has been performed using the FAP (Friction After Polishing) test equipment also known as the Wehner/Schulze machine. Laboratory method enables to compare the skid resistance of different types of wearing course under specified conditions simulating polishing processes. In addition, macrotexture measurements were made on the surface of each specimen using the Elatexure laser profile. Analysis of variance showed that at significance level α = 0.05, aggregate graining compositions as well as the PSV have a significant influence on the obtained values of the friction coefficient μm of the tested EAC pavements. The highest values of the μm have been obtained for EAC with the lowest amount of coarse aggregates (compositions A). In these cases the resistance to polishing of the aggregate does not significantly affect the friction coefficients. This is related to the large areas of cement mortar between the exposed coarse grains. Based on the analysis of microscope images, it was observed that the coarse aggregates were not sufficiently exposed. It has been proved that PSV significantly affected the coefficient of friction in the case of compositions B and C. This is caused by large areas of exposed coarse aggregate. The best parameters were achieved for the EAC pavements

  2. Asphalt Volcanism as a Model to Understand the Geochemical Nature of Pitch Lake, a Planetary Analog for Titan and the Implications towards Methane Flux into Earth's Atmosphere.

    Science.gov (United States)

    Khan, A.

    2016-12-01

    Pitch Lake is located in the southwest peninsula of the island near La Brea in Trinidad and Tobago, covering an area of approximately 46 hectares. It was discovered in the year 1595 and is the largest of three natural asphalt lakes that exist on Earth. Pitch Lake is a large oval shaped reservoir composed of dominantly hydrocarbon compounds, but also includes minor amounts of clay and muddy water. It is a natural liquid asphalt desert, which is nourished by a form of petroleum consisting of mostly asphaltines from the surrounding oil-rich region. The hydrocarbons mix with mud and gases under high pressure during upward seepage, and the lighter portion evaporates or is volatilized, which produces a high-viscosity liquid asphalt residue. The residue on and near the surface is a hydrocarbon matrix, which poses extremely challenging environmental conditions to microorganisms characterized by an average low water activity in the range of 0.49 to 0.75, recalcitrant carbon substrates, and toxic chemical compounds. Nevertheless, an active microbial community of archaea and bacteria, many of them novel strains, was found to inhabit the liquid hydrocarbon matrix of Pitch Lake. Geochemical analyses of minerals, done by our team, which revealed sulfates, sulfides, silicates, and metals, normally associated with deep-water hydrothermal vents leads to our new hypothetical model to describe the origins of Pitch Lake and its importance to atmospheric and earth sciences. Pitch Lake is likely the terrestrial equivalent of an offshore submarine asphalt volcano just as La Brea Tar Pits are in some ways an on-land version of the asphalt volcanoes discovered off shore of Santa Barbara by Valentine et al. in 2010. Asphalt volcanism possibly also creates the habitat for chemosynthetic life that is widespread in this lake, as reported by Schulze-Makuch et al. in 2011 and Meckenstock et al. in 2014.

  3. Cobalt carbide nanoprisms for direct production of lower olefins from syngas

    Science.gov (United States)

    Zhong, Liangshu; Yu, Fei; An, Yunlei; Zhao, Yonghui; Sun, Yuhan; Li, Zhengjia; Lin, Tiejun; Lin, Yanjun; Qi, Xingzhen; Dai, Yuanyuan; Gu, Lin; Hu, Jinsong; Jin, Shifeng; Shen, Qun; Wang, Hui

    2016-10-01

    Lower olefins—generally referring to ethylene, propylene and butylene—are basic carbon-based building blocks that are widely used in the chemical industry, and are traditionally produced through thermal or catalytic cracking of a range of hydrocarbon feedstocks, such as naphtha, gas oil, condensates and light alkanes. With the rapid depletion of the limited petroleum reserves that serve as the source of these hydrocarbons, there is an urgent need for processes that can produce lower olefins from alternative feedstocks. The ‘Fischer-Tropsch to olefins’ (FTO) process has long offered a way of producing lower olefins directly from syngas—a mixture of hydrogen and carbon monoxide that is readily derived from coal, biomass and natural gas. But the hydrocarbons obtained with the FTO process typically follow the so-called Anderson-Schulz-Flory distribution, which is characterized by a maximum C2-C4 hydrocarbon fraction of about 56.7 per cent and an undesired methane fraction of about 29.2 per cent (refs 1, 10, 11, 12). Here we show that, under mild reaction conditions, cobalt carbide quadrangular nanoprisms catalyse the FTO conversion of syngas with high selectivity for the production of lower olefins (constituting around 60.8 per cent of the carbon products), while generating little methane (about 5.0 per cent), with the ratio of desired unsaturated hydrocarbons to less valuable saturated hydrocarbons amongst the C2-C4 products being as high as 30. Detailed catalyst characterization during the initial reaction stage and theoretical calculations indicate that preferentially exposed {101} and {020} facets play a pivotal role during syngas conversion, in that they favour olefin production and inhibit methane formation, and thereby render cobalt carbide nanoprisms a promising new catalyst system for directly converting syngas into lower olefins.

  4. Sensitivity of tropical rainbelt over Africa and Middle East to dust shortwave absorption: Experiments using a high resolution AGCM

    KAUST Repository

    Bangalath, Hamza Kunhu

    2015-04-01

    Response of the rainbelt over Africa to dust direct radiative forcing has been an area of lively debate and is a subject of ongoing research. Previous modeling studies have contrasting results producing different amplitudes or even signs of responses. Uncertainties in the dust radiative forcing are thought to be the major cause of discrepancies in the simulated responses among various studies. The imaginary part of mineral dust shortwave refractive index, which defines the dust absorptivity, has a wide range of values estimated from various observational and modeling studies, as it depends on dust chemical composition and mineralogy. Balkanski et al. (2007) estimated dust shortwave refractive indices by assuming 3 different hematite contents, 0.9%, 1.5% and 2.7% by volume, which corresponds to inefficient, standard, and very efficient dust shortwave absorption, respectively. To investigate the sensitivity of the position and intensity of the tropical rainbelt over Africa and its extension to the Arabian Peninsula to dust shortwave absorption, we have conducted ensembles of numerical simulations for each of the three dust absorptivity scenarios using a high resolution Atmospheric General Circulation Model (AGCM), GFDL\\'s High Resolution Atmospheric Model (HiRAM), at a spatial resolution of 25 km. We found that the strength and the latitudinal extent of the rainbelt are very sensitive to dust shortwave absorption, as well as circulations at various spatiotemporal scales that drive the climate of the region. Reference: Balkanski, Y., M. Schulz, T. Claquin, and S. Guibert (2007), Reevaluation of mineral aerosol radiative forcings suggests a better agreement with satellite and AERONET data, Atmos. Chem. Phys., 7, 81 - 95.

  5. La fiaccola e la maschera: didascalie in immagini per il pensiero. Un esemplare pendant di Paolo De Matteis / The torch and the mask: captions by images for thought. A pair of paintings by Paolo De Matteis

    Directory of Open Access Journals (Sweden)

    Alessandro Rossi

    2015-12-01

    Full Text Available Abstract  Sintesi caleidoscopica dell’eros latino, le Metamorfosi di Ovidio sono state fondamentale riferimento sin dall’antichità per molti pittori che ne hanno ripreso i temi, cimentandosi anche nel non facile compito di rappresentare nella fissità della realizzazione pittorica la narrazione di ciò che, per definizione, è in movimento: la metamorfosi. Un pendant di dipinti, diviso ora fra Italia e Stati Uniti, raffigurante Apollo e Dafne e Pan e Siringa, rappresenta un significativo caso studio per dare avvio a una riflessione sui sottili rapporti che intercorrono fra l’invenzione del soggetto dovuta al poeta Ovidio, la modalità teorica con cui debba essere rappresentato tale soggetto, elaborata dal filosofo e committente inglese Conte di Shaftesbury e la realizzazione artistica di tale teoria dovuta al pittore cilentano Paolo De Matteis. Scopo ultimo della riflessione è quello di meglio comprendere, tanto storicamente quanto fenomenologicamente, l’intelligenza propria di un linguaggio pittorico che struttura dall’interno le immagini, rendendo efficace la loro capacità di mostrare sia ciò che le parole narrano sia ciò che il pensiero teorizza.   A kaleidoscopic synthesis of the Latin eros, Ovid’s Metamorphoses have been a fundamental point of reference, since ancient times, for the many painters who drew their subject-matter from this text and also undertook the far from simple task of using the static nature of the pictorial medium to represent the narration of what is – by definition – in motion: metamorphosis. A pair of paintings, now divided between Italy and the United States, depicting Apollo and Daphne and Pan and Syrinx, offers a significant case study for an initial reflection on the subtle relationships between the invention of a subject, a text by the poet Ovid, the theoretical mode of representing such a subject, devised by the English philosopher and patron, the Earl of Shaftesbury, and the artistic

  6. Las culpas del Rey y de su Favorito. El proceso a Alonso Ramírez de Prado (1607-1608

    Directory of Open Access Journals (Sweden)

    Giuseppe MROZEK ELISZEZYNSKI

    2013-01-01

    Full Text Available El enorme poder alcanzado por el letrado Alonso Ramírez de Prado en los primeros ocho años (1598-1606 del reinado de Felipe III fue resultado directodel dominio que su patrón, el duque de Lerma, ejerció sobre la corte y el joven rey. El 26 diciembre de 1606, su repentina detención puso fin a una rutilante carrera política y empezó un proceso, descuidado por mucho tiempo por los historiadores, junto al conde de Villalonga, don Pedro Franqueza. A través del análisis de la documentación oficial relativa a la causa de Ramírez de Prado, el presente trabajo pretende ilustrar las diferentes razones de la acusación y,sobre todo, los argumentos de la defensa, encargada al hijo del acusado, don Lorenzo Ramírez de Prado. El veredicto de culpabilidad emitido al final del proceso parecía anular cualquier argumento de la defensa. Sin embargo, el debate sobre la responsabilidad del soberano con respecto al poder de susfavoritos continuó a lo largo de las décadas siguientes.The huge power achieved by the jurist Alonso Ramírez de Prado in the firsteight years (1598-1606 of the reign of Philip III was a direct result of the supremacy of his patron, the Duke of Lerma, over the whole court and theyoung king. On December 26, 1606, his sudden arrest brought his brilliantcareer in politics to an end and started a trial, overlooked for a long time by historians in favor of the concurrent one against the Earl of Villalonga, PedroFranqueza. Through the analysis of the official documentation about the case of Ramírez de Prado, the article aims to illustrate the many reasons of the prosecution and, above all, the arguments of the defence, entrusted to his son, Lorenzo Ramírez de Prado. The verdict of guilty returned at the end of the process seemed to erase any argument of the defence. However, the debateabout the responsibilities of the sovereign in relation to the power of his favourites was destined to continue in the following decades

  7. Stereo and Solar Cycle 24

    Science.gov (United States)

    Kaise,r Michael L.

    2008-01-01

    The twin STEREO spacecrafi, launched in October 2006, are in heliocentric orbits near 4 AU with one spacecraft (Ahead) leading Earth in its orbit around the Sun and the other (Behind) trailing Earth. As viewed from the Sun, the STEREO spacecraft are continually separating from one another at about 45 degrees per year with Earth biseding the angle. At present, th@spaser=raft are a bit more than 45 degrees apart, thus they are able to each 'vie@ ground the limb's of the Sun by about 23 degrees, corresponding to about 1.75 days of solar rotation. Both spameraft contain an identical set of instruments including an extreme ultraviolet imager, two white light coronagraphs, tws all-sky imagers, a wide selection of energetic particle detectors, a magnetometer and a radio burst tracker. A snapshot of the real time data is continually broadcast to NOW-managed ground stations and this small stream of data is immediately sent to the STEREO Science Center and converted into useful space weather data within 5 minutes of ground receipt. The resulting images, particle, magnetometer and radio astronomy plots are available at j g i t , : gAs timqe conting ues ijnto . g solar cycle 24, the separation angle becomes 90 degrees in early 2009 and 180 degrees in early 201 1 as the activity heads toward maximum. By the time of solar maximum, STEREO will provide for the first time a view of the entire Sun with the mronagraphs and e*reme ultraviolet instruments. This view wilt allow us to follow the evolution of active regions continuously and also detect new active regions long before they pose a space weather threat to Earth. The in situ instruments will be able to provide about 7 days advanced notice of co-rotating structures in the solar wind. During this same intewal near solar maximum, the wide-angle imagers on STEREB will both be ;able to view EarlCP-dirsted CMEs in their plane-oPsky. When combined with Eat-lhorbiting assets available at that time, it seems solar cycle 24 will mark a

  8. Design of a water quality monitoring network for the Limpopo River Basin in Mozambique

    Science.gov (United States)

    Chilundo, M.; Kelderman, P.; O´keeffe, J. H.

    possible need for monthly monitoring of WQ. From this study it was concluded that a systematic WQ monitoring network composed of 16 stations would fit the conditions of the LRB. Ambient, earl warning, operational and effluents are the main monitoring types recommended. Additional research at a Basin scale was also recommended to identify the major sources of pollution, their transport and impacts to the downstream ecosystem.

  9. The use of physiological solutions or media in calcium phosphate synthesis and processing.

    Science.gov (United States)

    Tas, A Cuneyt

    2014-05-01

    This review examined the literature to spot uses, if any, of physiological solutions/media for the in situ synthesis of calcium phosphates (CaP) under processing conditions (i.e. temperature, pH, concentration of inorganic ions present in media) mimicking those prevalent in the human hard tissue environments. There happens to be a variety of aqueous solutions or media developed for different purposes; sometimes they have been named as physiological saline, isotonic solution, cell culture solution, metastable CaP solution, supersaturated calcification solution, simulated body fluid or even dialysate solution (for dialysis patients). Most of the time such solutions were not used as the aqueous medium to perform the biomimetic synthesis of calcium phosphates, and their use was usually limited to the in vitro testing of synthetic biomaterials. This review illustrates that only a limited number of research studies used physiological solutions or media such as Earle's balanced salt solution, Bachra et al. solutions or Tris-buffered simulated body fluid solution containing 27mM HCO3(-) for synthesizing CaP, and these studies have consistently reported the formation of X-ray-amorphous CaP nanopowders instead of Ap-CaP or stoichiometric hydroxyapatite (HA, Ca10(PO4)6(OH)2) at 37°C and pH 7.4. By relying on the published articles, this review highlights the significance of the use of aqueous solutions containing 0.8-1.5 mMMg(2+), 22-27mM HCO3(-), 142-145mM Na(+), 5-5.8mM K(+), 103-133mM Cl(-), 1.8-3.75mM Ca(2+), and 0.8-1.67mM HPO4(2-), which essentially mimic the composition and the overall ionic strength of the human extracellular fluid (ECF), in forming the nanospheres of X-ray-amorphous CaP. Copyright © 2013 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

  10. Inquiry in early years science teaching and learning: Curriculum design and the scientific story

    Science.gov (United States)

    McMillan, Barbara Alexander

    2001-07-01

    Inquiry in school science, as conceived by the authors of the Common Framework of Science Learning Outcomes K--12, is dependent upon four areas of skills. These are the skills of initiating and planning, performing and recording, analysing and interpreting, and communication and teamwork that map onto what Hodson calls the five phases of scientific inquiry in school science: initiation, design and planning, performance, interpretation, and reporting and communicating. This study looked at initiation in a multiage (Grades 1--3) classroom, and the curriculum, design tools, and inquiry acts believed to be necessary precursors of design and planning phases whether the inquiry in which young children engage is archival or laboratory investigation. The curriculum was designed to build upon children's everyday biological knowledge and through a series of carefully organized lessons to help them to begin to build scientifically valid conceptual models in the area of animal life cycles. The lessons began with what is called benchmark-invention after the historical work of Robert Karplus and the contemporary work of Earl Hunt and Jim Minstrell. The introduction of a biological concept was followed by a series of exploration activities in which children were encouraged to apply the concept invented in the benchmark lesson. Enlargement followed. This was the instructional phase in which children were helped to establish scientifically valid relationships between the invented concept and other biological concepts. The pre-instruction and post-instruction interview data suggest that the enacted curriculum and sequence in which the biological knowledge was presented helped the nineteen children in the study to recognize the connections and regularities within the life cycles of the major groupings of animals, and to begin to build scientific biological conceptual models. It is, however, argued that everyday biology, in the form of the person analogy, acts as an obstacle to

  11. Genetic diversity and population structure in the threatened Oregon silverspot butterfly (Speyeria zerene hippolyta) in western Oregon and northwestern California— Implications for future translocations and the establishment of new populations

    Science.gov (United States)

    Miller, Mark P.; Mullins, Thomas D.; Haig, Susan M.

    2016-09-20

    Executive SummaryWe present results of population genetic analyses performed on Oregon silverspot butterflies (OSB; Speyeria zerene hippolyta) in western Oregon and northwestern California. We used DNA sequences from a 561-base pair region of the mitochondrial cytochrome oxidase subunit I (COI) gene for a dataset comprised of 112 S. z. hippolyta and 32 S. z. gloriosa individuals collected at 9 locations in western Oregon and northwestern California. The most pertinent findings thus far are summarized as follows:Among OSB populations, genetic diversity is lowest at Mount Hebo and highest at Rock Creek and Bray Point. Of the 32 haplotypes detected in OSB, only 2 were shared among populations (1 shared by Mount Hebo, Cascade Head, Bray Point, and Rock Creek, and 1 shared by Rock Creek and Lake Earl). The remaining 30 haplotypes were identified in individual populations, highlighting the strong differentiation among sites. It is unclear if the shared haplotypes represent widespread, naturally occurring genetic variation or if allele sharing among populations is due to translocation history.Using full siblings of individuals that were released at Rock Creek and Bray Point in 2012 as comparison standards, the analyses suggest that 54 percent of the sampled individuals from Bray Point were naturally recruited into the population and were not originating from the 2012 release of captive reared individuals. Likewise, 33 percent of the analyzed individuals from Rock Creek were naturally recruited. Both of these estimates may be underestimates if the shared alleles that we identified among populations are naturally occurring and not a product of the 2012 translocations.The results suggest that there are about 12–13 COI haplotypes in the Mount Hebo population. The U.S. Fish and Wildlife Service anticipates using Mount Hebo as the source of individuals when establishing new populations in the future. Nonlinear regression models based on a series of rarefaction analyses

  12. The development and characterization of a primarily mineral calcium phosphate - poly(epsilon-caprolactone) biocomposite

    Science.gov (United States)

    Dunkley, Ian Robert

    of the sintered calcium phosphate ceramic. After infiltration, these biocomposite materials demonstrated an increase in compressive strength, flexural strength and Young's modulus with increasing ceramic content and met design targets for use as a cervical fusion prosthesis. The biocomposite was amenable to shaping and drilling and was found to maintain its strength after 30 days immersion in Earle's Balanced Salt.

  13. Assessing the Effectiveness of the Cone of Probability as a Visual Means of Communicating Scientific Forecasts

    Science.gov (United States)

    Orlove, B. S.; Broad, K.; Meyer, R.

    2010-12-01

    exceeded the levels that could have been reached with fuller preparation. Though no hurricanes in 2010 have yet made landfall at the time of the writing of this abstract, coordination has been fuller to support evacuations of vulnerable coastal regions of North Carolina for Hurricane Earl. Through an examination of interviews, newspaper accounts, public comments on the NHC’s site and on weather blogs, we trace the relative weight of these three changes in the improvements in response to forecasts. We conclude that forecast providers should consider more formal, rigorous pretesting of forecast graphics, using standard social science techniques, in order to minimize the probability of misinterpretation.

  14. Radioimmunological analysis of circadian rhythms of cortisol and melatonin in saliva

    International Nuclear Information System (INIS)

    Demel, A.W.

    1990-12-01

    Since blood cortisol (F) and melatonin (MTL) display a circadian secretion pattern and since the saliva concentration of these hormones is an excellent indicator of its blood levels the measurement of salivary F and MLT may be used for examining circadian rhythmicity. In these study the relationship between salivary F and MLT was explored. For this purpose it was necessary first to establish and validate a radioimmunoassay for F in saliva: salivary F was determined by a direct radioimmunoassay using cortisol-3-(O-carboxymethyl) oximino-(2- ( 125 I)iodohistamin) as tracer and cortisol-3-CMO-BSA antiserum. The parallel measurement of F levels in saliva and serum of adults gave an excellent correlation (r=0.87, p 0.00956x ). Serum F was assayed on the Abott TDX-System using a radioimmunofluorescence method. Secondly, using this assay the circadian saliva F pattern was determined as well as the pattern of salivary MLT in 9 young, healthy volunteers. For saliva MLT estimations a previously published method was applied (SCHULZ et al 1990). Using a computerized program (RHYTHM) written by EVE v. CAUTER (1979), the hormone data of each individuum were examined for circadian rhythmicity and its acrophases (time of occurrence of the maximum of a sinusoid fitted to the data). The F acrophase occured between 7:00 and 12:00 h (Mean: 8:06 h, SD: 93.8 min). The acrophase for MLT was found between 0:00 and 6:00 h (Mean: 3:33 h, SD: 104.4 min). There was a phase difference between both hormones of 3 to 7 hours (Mean: 292.5 min, SD: 74.7 min). The easy stress-free non-invasive nature of saliva collection makes saliva to one of the most accessible body fluids and of high value in studying the circadian system in healthy humans as well as in infants, children, pregnant women and anaemic patients. Measurements of salivary F and MLT may help to elucidate not only the circadian rhythms of these hormones under normal and pathological conditions but it may also provide insight in

  15. Laboratory polarization and permittivity measurements to interpret dust polarimetric observations and in-situ radar studies. Significance for Rosetta mission at 67P/Churyumov-Gerasimenko

    Science.gov (United States)

    Levasseur-Regourd, Anny-Chantal; Brouet, Yann; Hadamcik, Edith; Heggy, Essam; Hines, Dean; Lasue, Jérémie; Renard, Jean-Baptiste

    2015-08-01

    Polarimetric astronomical observations on dust clouds and regolithic surfaces require laboratory simulations on samples to provide information on properties (size distribution, porosity, refractive index) of the scattering media. Similarly, in-situ radar investigations in the solar system require laboratory studies on samples to infer physical properties (e.g. porosity, ice/dust ratio) of sub-surfaces and interiors. Recent developments are illustrated with present studies related to the Rosetta mission, which begun its rendezvous with comet 67P/Churyumov-Gerasimeko (C-G) and landed the Philae module on its nucleus in 2014.We will summarize laboratory simulations with the PROGRA2 suite of instruments that study (in the visible to near IR domain) the polarimetric properties of dust samples in microgravity conditions or on surfaces [1], with emphasis on the interpretation of polarimetric observations of C-G, during its previous perihelion passages from Earth observatories, and currently from HST [2,3]. The presence of large dust particles in the pre-perihelion coma previously inferred from remote observations agrees with Rosetta ground truth [4]. We will also present measurements on the permittivity (in the millimeter to meter domain) of various dust samples, with emphasis on porous samples [5,6]. Results provide constraints on the properties of the subsurface and interior of C-G, as explored by MIRO on Rosetta and CONSERT on Philae.Such studies are relevant for the interpretation of polarimetric observations of other dust clouds (e.g. debris disks, interplanetary dust cloud, clouds in planetary atmospheres) and surfaces (e.g. planets, moons), as well as for those of other radar characterization studies (e.g. Mars, moons, asteroids).[1] Levasseur-Regourd et al. In Polarization of stars and planetary systems, Cambridge UP, in press 2015.[2] Hadamcik et al. A&A 517 2010.[3] Hines and Levasseur-Regourd, PSS submitted 2015.[4] Schulz et al. Nature 518 2015.[5] Heggy et al

  16. Extending the radial diffusion model of Falthammar to non-dipole background field

    Energy Technology Data Exchange (ETDEWEB)

    Cunningham, Gregory Scott [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-05-26

    A model for radial diffusion caused by electromagnetic disturbances was published by Falthammar (1965) using a two-parameter model of the disturbance perturbing a background dipole magnetic field. Schulz and Lanzerotti (1974) extended this model by recognizing the two parameter perturbation as the leading (non--dipole) terms of the Mead Williams magnetic field model. They emphasized that the magnetic perturbation in such a model induces an electric ield that can be calculated from the motion of field lines on which the particles are ‘frozen’. Roederer and Zhang (2014) describe how the field lines on which the particles are frozen can be calculated by tracing the unperturbed field lines from the minimum-B location to the ionospheric footpoint, and then tracing the perturbed field (which shares the same ionospheric footpoint due to the frozen -in condition) from the ionospheric footpoint back to a perturbed minimum B location. The instantaneous change n Roederer L*, dL*/dt, can then be computed as the product (dL*/dphi)*(dphi/dt). dL*/Dphi is linearly dependent on the perturbation parameters (to first order) and is obtained by computing the drift across L*-labeled perturbed field lines, while dphi/dt is related to the bounce-averaged gradient-curvature drift velocity. The advantage of assuming a dipole background magnetic field, as in these previous studies, is that the instantaneous dL*/dt can be computed analytically (with some approximations), as can the DLL that results from integrating dL*/dt over time and computing the expected value of (dL*)^2. The approach can also be applied to complex background magnetic field models like T89 or TS04, on top of which the small perturbations are added, but an analytical solution is not possible and so a numerical solution must be implemented. In this talk, I discuss our progress in implementing a numerical solution to the calculation of DL*L* using arbitrary background field models with simple electromagnetic

  17. Changes in corneal endothelium cell characteristics after cataract surgery with and without use of viscoelastic substances during intraocular lens implantation

    Directory of Open Access Journals (Sweden)

    Schulze SD

    2015-11-01

    Full Text Available Stephan D Schulze,1 Thomas Bertelmann,1 Irena Manojlovic,2 Stefan Bodanowitz,2 Sebastian Irle,3 Walter Sekundo11Department of Ophthalmology, Philipps University of Marburg, Marburg, 2Private Practice and Ambulatory Surgical Center, Bremen, 3Freelance Statistician, Friedberg, GermanyPurpose: To evaluate whether the use of balanced salt solution (BSS or an ophthalmic viscoelastic device (OVD during hydrophilic acrylic intraocular lens (IOL implantation variously impacts corneal endothelial cell characteristics in eyes undergoing uneventful phacoemulsifications.Methods: Prospective nonrandomized observational clinical trial. Patients were assigned either to the BSS plus® or to the OVD Z-Celcoat™ group depending on the substance used during IOL implantation. Corneal endothelium cell characteristics were obtained before, 1 week, and 6 weeks after surgery. Intraoperative parameters (eg, surgery time, phacoemulsification energy were recorded.Results: Ninety-seven eyes were assigned to the BSS plus and 86 eyes to the Z-Celcoat group. Preoperative corneal endothelium cell density (ECD and endothelium cell size were 2,506±310 cells/mm2/2,433±261 cells/mm2 and 406±47 µm2/416±50 µm2 (P=0.107/P=0.09. After 1 and 6 weeks, ECD decreased and endothelium cell size increased significantly in both groups (each P<0.001 without significant differences between both groups (each P>0.05. Irrigation–aspiration suction time (30.3±16.6 versus 36.3±14.5 seconds and overall surgical time (7.2±1.2 versus 8.0±1.4 minutes were significantly longer in the OVD Z-Celcoat group (each P<0.001. No complications or serious side effects occurred.Conclusion: Implantation of a hydrophilic acrylic IOL under BSS infusion seems to be a useful and faster alternative in experienced hands without generating higher ECD loss rates.Keywords: phacoemulsification, ophthalmic viscoelastic device, endothelial cell density, IOL

  18. Real-world usage and clinical outcomes of alectinib among post-crizotinib progression anaplastic lymphoma kinase positive non-small-cell lung cancer patients in the USA

    Directory of Open Access Journals (Sweden)

    DiBonaventura MD

    2017-12-01

    Full Text Available Marco D DiBonaventura,1 William Wong,2 Bijal Shah-Manek,3,4 Mathias Schulz2 1Ipsos Healthcare, Global Evidence, Value & Access, New York, NY, 2Genentech, US Medical Affairs, San Francisco, CA, 3Ipsos Healthcare, Global Evidence, Value & Access, San Francisco, CA, 4College of Pharmacy, Touro University California, CA, USA Background: Alectinib is an approved treatment for anaplastic lymphoma kinase (ALK-positive patients with advanced non-small-cell lung cancer. Despite positive supporting clinical data, there is a lack of real-world information on the usage and patient outcomes of those treated with alectinib post-crizotinib progression. Methods: Participating oncologists (N=95 in the USA were recruited from an online physician panel to participate in a retrospective patient chart review. Physicians randomly selected eligible patients (ie, patients who progressed on crizotinib as their first ALK inhibitor and were treated with alectinib as their second ALK inhibitor, collected demographics and clinical history from their medical charts, and entered the data into an online data collection form. Results: A total of N=207 patient charts were included (age: 60.1±10.4 years; 53.6% male. The patients in our sample were older (median age of 60 vs 53 years, were more likely to be current smokers (12% vs 1%, had better performance status (45% vs 33% had an Eastern Cooperative Oncology Group [ECOG] of 0, and were less likely to have an adenocarcinoma histology (83% vs 96% relative to published clinical trials. The objective response rate was higher than in clinical trials (67.1% vs 51.3%, respectively as was the disease control rate (89.9% vs 78.8%, respectively, though it varied by race/ethnicity, ECOG, and prior treatment history. Discontinuation (0.0% and dose reductions (3.4% due to adverse events were uncommon in alectinib.Conclusion: Patients using alectinib post-crizotinib in clinical practice are older, more racially/ethnically and histologically

  19. Mediatisation or PR-ization of Public--Media Communication--Analysis of Mediated Communication of Zoran Milanović.

    Science.gov (United States)

    Tanta, Ivan; Lesinger, Gordana

    2015-12-01

    Politicians and their public relations advisors depend on the mass communication media to transmit messages dailyand communicate effectively. The development of the mass media, from traditional to new, has changed the working conditions of these professions where one inevitably affects the other. Consequently, the way of formatting information in the newshas changed, along with the way of monitoring the political developments and informs the public on political activities. Amajor role in this process, over and above the political actors, has advisers for public relations, who choose moments andevents to publicise (PR-ization). With the increasing influence of public relations to media reports, politics also changes thepicture of the media and the impact on media coverage. Similarly, the impact on the manner in which the media reportprocess, what topics will be discussed topics and what tone the given information will have. We are living in a world characterized by mediation (Mazzoleni and Schulz, 1999) of the politics and the society as a whole, because politics and publicrelations necessarily need the media to communicate with their audiences. In this regard, we can talk about PR-izationmedia as the fundamental role of public relations practitioners affect attitudes, which skillfully make careful design ofmessages and events that are not included herein are the three professions each other should one without the other does notmake sense. This paper will focus on the influence of the media on politics and on influence of the public relations as profession in the content media perception. In view of the drawn by daily public appearances of Prime Minister, Zoran Milanovi6,and as says Lali63 few politics-related phenomena have over the past twenty years engaged so many reviews by experts andscholars as the Prime Minister's rhetoric. The particular form of the political communication will be reviewed in this paper.Through the interviews and the content analysis of key

  20. Playing hide and seek with repeats in local and global de novo transcriptome assembly of short RNA-seq reads.

    Science.gov (United States)

    Lima, Leandro; Sinaimeri, Blerina; Sacomoto, Gustavo; Lopez-Maestre, Helene; Marchet, Camille; Miele, Vincent; Sagot, Marie-France; Lacroix, Vincent

    2017-01-01

    The main challenge in de novo genome assembly of DNA-seq data is certainly to deal with repeats that are longer than the reads. In de novo transcriptome assembly of RNA-seq reads, on the other hand, this problem has been underestimated so far. Even though we have fewer and shorter repeated sequences in transcriptomics, they do create ambiguities and confuse assemblers if not addressed properly. Most transcriptome assemblers of short reads are based on de Bruijn graphs (DBG) and have no clear and explicit model for repeats in RNA-seq data, relying instead on heuristics to deal with them. The results of this work are threefold. First, we introduce a formal model for representing high copy-number and low-divergence repeats in RNA-seq data and exploit its properties to infer a combinatorial characteristic of repeat-associated subgraphs. We show that the problem of identifying such subgraphs in a DBG is NP-complete. Second, we show that in the specific case of local assembly of alternative splicing (AS) events, we can implicitly avoid such subgraphs, and we present an efficient algorithm to enumerate AS events that are not included in repeats. Using simulated data, we show that this strategy is significantly more sensitive and precise than the previous version of KisSplice (Sacomoto et al. in WABI, pp 99-111, 1), Trinity (Grabherr et al. in Nat Biotechnol 29(7):644-652, 2), and Oases (Schulz et al. in Bioinformatics 28(8):1086-1092, 3), for the specific task of calling AS events. Third, we turn our focus to full-length transcriptome assembly, and we show that exploring the topology of DBGs can improve de novo transcriptome evaluation methods. Based on the observation that repeats create complicated regions in a DBG, and when assemblers try to traverse these regions, they can infer erroneous transcripts, we propose a measure to flag transcripts traversing such troublesome regions, thereby giving a confidence level for each transcript. The originality of our work when

  1. Effects of interfacial micromotions on vitality and differentiation of human osteoblasts.

    Science.gov (United States)

    Ziebart, J; Fan, S; Schulze, C; Kämmerer, P W; Bader, R; Jonitz-Heincke, A

    2018-02-01

    considered. Cite this article : J. Ziebart, S. Fan, C. Schulze, P. W. Kämmerer, R. Bader, A. Jonitz-Heincke. Effects of interfacial micromotions on vitality and differentiation of human osteoblasts. Bone Joint Res 2018;7:187-195. DOI: 10.1302/2046-3758.72.BJR-2017-0228.R1.

  2. Physician Rating Websites: What Aspects Are Important to Identify a Good Doctor, and Are Patients Capable of Assessing Them? A Mixed-Methods Approach Including Physicians' and Health Care Consumers' Perspectives.

    Science.gov (United States)

    Rothenfluh, Fabia; Schulz, Peter J

    2017-05-01

    of care were also judged to be very important, but both parties agreed that they would not be evaluable by health care consumers. Health care consumers in Switzerland show a high appraisal of the importance of physician-approved criteria for assessing health care performance and a moderate self-perception of how capable they are of assessing the quality and performance of a physician. This study supports that health care consumers are differentiating between aspects they perceive they would be able to evaluate after a visit to a physician (such as attributes of structure and the interpersonal skills of a doctor), and others that lay beyond their ability to make an accurate judgment about (such as technical skills of a physician and outcome of care). ©Fabia Rothenfluh, Peter J Schulz. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 01.05.2017.

  3. Magnetic and elastic anisotropy in magnetorheological elastomers using nickel-based nanoparticles and nanochains

    Energy Technology Data Exchange (ETDEWEB)

    Landa, Romina A.; Soledad Antonel, Paula; Ruiz, Mariano M.; Negri, R. Martín, E-mail: rmn@qi.fcen.uba.ar [Departamento de Química Inorgánica, Analítica y Química Física, Facultad de Ciencias Exactas y Naturales, Instituto de Química Física de Materiales, Ambiente y Energía (INQUIMAE), Universidad de Buenos Aires, Ciudad Universitaria, Pabellón II, C1428EGA Buenos Aires (Argentina); Perez, Oscar E. [Departamento de Industrias, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires (Argentina); Butera, Alejandro [Centro Atómico Bariloche (Comisión Nacional de Energía Atómica. Argentina) and Instituto Balseiro, Universidad Nacional de Cuyo, Mendoza (Argentina); Jorge, Guillermo [Instituto de Ciencias, Universidad Nacional de General Sarmiento, Buenos Aires (Argentina); Oliveira, Cristiano L. P. [Grupo de Fluidos Complexos, Instituto de Física, Universidade de São Paulo, São Paulo (Brazil)

    2013-12-07

    Nickel (Ni) based nanoparticles and nanochains were incorporated as fillers in polydimethylsiloxane (PDMS) elastomers and then these mixtures were thermally cured in the presence of a uniform magnetic field. In this way, macroscopically structured-anisotropic PDMS-Ni based magnetorheological composites were obtained with the formation of pseudo-chains-like structures (referred as needles) oriented in the direction of the applied magnetic field when curing. Nanoparticles were synthesized at room temperature, under air ambient atmosphere (open air, atmospheric pressure) and then calcined at 400 °C (in air atmosphere also). The size distribution was obtained by fitting Small Angle X-ray Scattering (SAXS) experiments with a polydisperse hard spheres model and a Schulz-Zimm distribution, obtaining a size distribution centered at (10.0 ± 0.6) nm with polydispersivity given by σ = (8.0 ± 0.2) nm. The SAXS, X-ray powder diffraction, and Transmission Electron Microscope (TEM) experiments are consistent with single crystal nanoparticles of spherical shape (average particle diameter obtained by TEM: (12 ± 1) nm). Nickel-based nanochains (average diameter: 360 nm; average length: 3 μm, obtained by Scanning Electron Microscopy; aspect ratio = length/diameter ∼ 10) were obtained at 85 °C and ambient atmosphere (open air, atmospheric pressure). The magnetic properties of Ni-based nanoparticles and nanochains at room temperature are compared and discussed in terms of surface and size effects. Both Ni-based nanoparticles and nanochains were used as fillers for obtaining the PDMS structured magnetorheological composites, observing the presence of oriented needles. Magnetization curves, ferromagnetic resonance (FMR) spectra, and strain-stress curves of low filler's loading composites (2% w/w of fillers) were determined as functions of the relative orientation with respect to the needles. The results indicate that even at low loadings it is

  4. Content, Quality, and Assessment Tools of Physician-Rating Websites in 12 Countries: Quantitative Analysis.

    Science.gov (United States)

    Rothenfluh, Fabia; Schulz, Peter J

    2018-06-14

    financial goals that the majority of physician-rating websites, especially the ones that are commercially owned, pursue. ©Fabia Rothenfluh, Peter J Schulz. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 14.06.2018.

  5. Evidence for a strong sulfur-aromatic interaction derived from crystallographic data.

    Science.gov (United States)

    Zauhar, R J; Colbert, C L; Morgan, R S; Welsh, W J

    2000-03-01

    Letters, 1985, Vol. 190, pp. 209-213), as well as studies involving molecular mechanics (G. Nemethy and H. A. Scheraga, Biochemistry and Biophysics Research Communications, 1981, Vol. 98, pp. 482-487) and quantum chemical calculations (B. V. Cheney, M. W. Schulz, and J. Cheney, Biochimica Biophysica Acta, 1989, Vol. 996, pp.116-124; J. Pranata, Bioorganic Chemistry, 1997, Vol. 25, pp. 213-219)-all of which point to the possible importance of the sulfur-aromatic interaction. However, the preferred geometry of the interaction, as determined from our analysis of the small-molecule crystal data, differs significantly from that found by other approaches. Copyright 2000 John Wiley & Sons, Inc.

  6. Exploring the Measurement Properties of the eHealth Literacy Scale (eHEALS) Among Baby Boomers: A Multinational Test of Measurement Invariance.

    Science.gov (United States)

    Sudbury-Riley, Lynn; FitzPatrick, Mary; Schulz, Peter J

    2017-02-27

    random samples drawn from an increasingly important cohort. The results give increased confidence to researchers using the scale in a range of eHealth assessment applications from primary care to health promotions. ©Lynn Sudbury-Riley, Mary FitzPatrick, Peter J Schulz. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 27.02.2017.

  7. Erythroxylum pungens elicits vasorelaxation by reducing intracellular calcium concentration in vascular smooth muscle cells of rats

    Directory of Open Access Journals (Sweden)

    Aurylene C. Oliveira

    2012-01-01

    Full Text Available The cardiovascular effects elicited by the ethanolic extract obtained from the roots of Erythroxylum pungens O.E. Schulz, Erythroxylaceae (EEEP and the vasorelaxant effect induced by its main tropane alkaloid (pungencine were investigated. In normotensive rats, administration of EEEP (1, 10, 30 and 60 mg/kg i.v., randomly produced dose-dependent hypotension (-2±1, -7±0.5 -17.6±1, -24±1 Δ mmHg, n=5 followed by tachycardia (3±0.5, 7±2, 7.1±1, 10±5 Δ bpm, n=5. In intact phenylephrine (Phe, 10 µM-pre-contracted rings, EEEP (0.01-500 µg/mL induced concentration-dependent vasorelaxation (EC50 13.7±5.5 µg/mL, Maximal Response= 92±2.6%, and this effect was unchanged after the removal of the vascular endothelium (EC50 27.2±4.7 µg/ml, Maximal Response= 88.3±3.3 %. In KCl (80 mM-pre-contracted-endothelium-denuded rings, EEEP elicited concentration-dependent relaxation (EC50= 128.2±11.2 µg/mL, Maximal Response 76.8±3.4%. Vasorelaxation has also been achieved with tonic contractions evoked by the L-type Ca2+ channel agonist Bay K 8644 (EC50 80.2±9.1 µg/mL, Maximal Response 86.3±8.3%. In addition, in a depolarizing medium, EEEP inhibited CaCl2 (30-500 µg/mL induced contractions and caused a concentration-dependent rightward shift of the relaxation curves. Lastly, the tropane alkaloid pungencine caused vasorelaxation in mesenteric arteries resembling to the EEEP responses. These results suggests that EEEP induces hypotension and vasorelaxation, at least in part, due to the reduction in [Ca2+]i in vascular smooth muscle cells.

  8. Development of a Questionnaire to Measure the Attitudes of Laypeople, Physicians, and Psychotherapists Toward Telemedicine in Mental Health.

    Science.gov (United States)

    Tonn, Peter; Reuter, Silja Christin; Kuchler, Isabelle; Reinke, Britta; Hinkelmann, Lena; Stöckigt, Saskia; Siemoneit, Hanna; Schulze, Nina

    2017-10-03

    -based interventions in psychiatry and psychotherapy and should be used in different studies in this field in the future to evaluate and reflect the attitude of the participants. ©Peter Tonn, Silja Christin Reuter, Isabelle Kuchler, Britta Reinke, Lena Hinkelmann, Saskia Stöckigt, Hanna Siemoneit, Nina Schulze. Originally published in JMIR Mental Health (http://mental.jmir.org), 03.10.2017.

  9. Adaptive practices in heart failure care teams: implications for patient-centered care in the context of complexity

    Directory of Open Access Journals (Sweden)

    Tait GR

    2015-08-01

    Full Text Available Glendon R Tait,1 Joanna Bates,2 Kori A LaDonna,3 Valerie N Schulz,4 Patricia H Strachan,5 Allan McDougall,3 Lorelei Lingard3 1Department of Psychiatry and Division of Medical Education, Dalhousie University, Halifax, NS, 2Centre for Health Education Scholarship, Vancouver General Hospital, Vancouver, BC, 3Centre for Education Research and Innovation, Schulich School of Medicine and Dentistry, Western University, 4Palliative Care, London Health Sciences Centre, University Hospital, London; 5School of Nursing, McMaster University, Hamilton, ON, Canada Background: Heart failure (HF, one of the three leading causes of death, is a chronic, progressive, incurable disease. There is growing support for integration of palliative care’s holistic approach to suffering, but insufficient understanding of how this would happen in the complex team context of HF care. This study examined how HF care teams, as defined by patients, work together to provide care to patients with advanced disease. Methods: Team members were identified by each participating patient, generating team sampling units (TSUs for each patient. Drawn from five study sites in three Canadian provinces, our dataset consists of 209 interviews from 50 TSUs. Drawing on a theoretical framing of HF teams as complex adaptive systems (CAS, interviews were analyzed using the constant comparative method associated with constructivist grounded theory. Results: This paper centers on the dominant theme of system practices, how HF care delivery is reported to work organizationally, socially, and practically, and describes two subthemes: “the way things work around here”, which were commonplace, routine ways of doing things, and “the way we make things work around here”, which were more conscious, effortful adaptations to usual practice in response to emergent needs. An adaptive practice, often a small alteration to routine, could have amplified effects beyond those intended by the innovating team

  10. Epidemiology of respiratory syncytial virus in children ≤2 years of age hospitalized with lower respiratory tract infections in the Russian Federation: a prospective, multicenter study

    Directory of Open Access Journals (Sweden)

    Vladimir Tatochenko

    2010-09-01

    Full Text Available Vladimir Tatochenko1, Vasily Uchaikin2, Aleksandr Gorelov3, Konstantin Gudkov4, Andrew Campbell5, Gregory Schulz5, Rebecca Prahl5, Gerard Notario51Scientific Centre of Children’s Health, Russian Academy of Medical Sciences, Lomonosovskiy Prospect, Moscow, Russia; 2Russian State Medical University of Roszdrav, Moscow, Russia; 3Central Scientific Research Institution of Epidemiology, Moscow, Russia; 4Abbott Laboratories LLC, Khimki, Moscow, Russia; 5Abbott Laboratories, Abbott Park, IL, USABackground: Respiratory syncytial virus (RSV is the leading cause of severe lower respiratory tract infections among infants and young children, and is responsible for an estimated four million deaths per year globally. A monthly injection of palivizumab has been used for prophylaxis of serious RSV infections among high-risk children in 71 countries since 1998 and approval for use in the Russian Federation was obtained in February 2010. A recommendation for RSV prophylaxis in the Russian Federation would require knowledge of the prevalence and seasonality of RSV in that country.Methods: In a prospective, multicenter, epidemiological study of the prevalence, seasonality, and peak occurrence of RSV infection, children aged ≤2 years hospitalized for lower respiratory tract infections in three regions of the Russian Federation, from September 2008 through April 2009, were screened and tested for RSV using rapid immunochromatography of nasopharyngeal lavage. For subjects who were tested positive, hospitalization data were collected.Results: Of 519 children aged ≤2 years enrolled from September 11, 2008 through April 26, 2009, 197 tested positive for RSV (38.0%, 95% CI: 33.8, 42.3. The onset of the 2008–2009 RSV season in the Russian Federation occurred in late October 2008, similar to what is observed in other northern temperate zones. Peak activity occurred in early April 2009, when 62% of children enrolled tested positive for RSV.Conclusion: The prevalence

  11. Pelagic community production and carbon-nutrient stoichiometry under variable ocean acidification in an Arctic fjord

    Directory of Open Access Journals (Sweden)

    A. Silyakova

    2013-07-01

    Full Text Available Net community production (NCP and carbon to nutrient uptake ratios were studied during a large-scale mesocosm experiment on ocean acidification in Kongsfjorden, western Svalbard, during June–July 2010. Nutrient depleted fjord water with natural plankton assemblages, enclosed in nine mesocosms of ~ 50 m3 in volume, was exposed to pCO2 levels ranging initially from 185 to 1420 μatm. NCP estimations are the cumulative change in dissolved inorganic carbon concentrations after accounting for gas exchange and total alkalinity variations. Stoichiometric coupling between inorganic carbon and nutrient net uptake is shown as a ratio of NCP to a cumulative change in inorganic nutrients. Phytoplankton growth was stimulated by nutrient addition half way through the experiment and three distinct peaks in chlorophyll a concentration were observed during the experiment. Accordingly, the experiment was divided in three phases. Cumulative NCP was similar in all mesocosms over the duration of the experiment. However, in phases I and II, NCP was higher and in phase III lower at elevated pCO2. Due to relatively low inorganic nutrient concentration in phase I, C : N and C : P uptake ratios were calculated only for the period after nutrient addition (phase II and phase III. For the total post-nutrient period (phase II + phase III ratios were close to Redfield, however they were lower in phase II and higher in phase III. Variability of NCP, C : N and C : P uptake ratios in different phases reflects the effect of increasing CO2 on phytoplankton community composition and succession. The phytoplankton community was composed predominantly of haptophytes in phase I, prasinophytes, dinoflagellates, and cryptophytes in phase II, and haptophytes, prasinophytes, dinoflagellates and chlorophytes in phase III (Schulz et al., 2013. Increasing ambient inorganic carbon concentrations have also been shown to promote primary production and carbon assimilation. For this study, it is

  12. Leaching of transuranics observed in lysimeter experiments

    International Nuclear Information System (INIS)

    Eriksson, A.; Fredriksson, L.

    1994-01-01

    Transuranic elements in fallout are generally bound in oxide particles, size from submicron to several microns. During the fallout they can be intercepted on plant covers or reach the soil surface. The particles can be re-suspended to the air and reach other residence sites, be linked into the food chain or be redistributed in other ways (Cf Essington et al. 1976) before eventually being incorporated into the soil. The fate of such particles in the soil depends on the size and on the nature of the particulate matter and on environmental factors, the climate and the properties of the soil. In a dry climate the particles tend to be kept intact long time, (Schulz et al. 1976) and they are more easily redistributed than in a humid climate with plant covered moist and living soils. In the former the particles move more easily in the soil profile than in the latter, the particle matter is very slowly dissolved and the average availability of the deposited nuclides for plant uptake can be assumed to be comparatively low. The downward movements of the particles or nuclide compounds bound to small soil particles are enhanced by the swelling and shrinking of soil caused by absorption and depletion of water during the season. Cracks and fissures are created and closed several times a year in soils rich in colloidal material. Sandy soils with coarse material have less cracks, but in dry conditions the empty pore space may allow transport of fine particles. The coarser material also has less specific area and sorption capacity. The nuclide compounds leached with the drainage water in coarse soils should be less retarded than in clays (Cf. Rai and Serne, 1977; Nishita and Haug, 1979 and Rai et al., 1980). The lysimeter installation used for the study reported below was primarily designed to study the plant uptake of transuranics from a number of Swedish soils. However, as such an installation in many ways well simulate field conditions and at the same time is a closed system

  13. The Impact of Discovering Life beyond Earth

    Science.gov (United States)

    Dick, Steven J.

    2016-01-01

    Introduction: astrobiology and society Steven J. Dick; Part I. Motivations and Approaches. How Do We Frame the Problems of Discovery and Impact?: Introduction; 1. Current approaches to finding life beyond earth, and what happens if we do Seth Shostak; 2. The philosophy of astrobiology: the Copernican and Darwinian presuppositions Iris Fry; 3. History, discovery, analogy: three approaches to the impact of discovering life beyond earth Steven J. Dick; 4. Silent impact: why the discovery of extraterrestrial life should be silent Clément Vidal; Part II. Transcending Anthropocentrism. How Do We Move beyond our Own Preconceptions of Life, Intelligence and Culture?: Introduction; 5. The landscape of life Dirk Schulze-Makuch; 6. The landscape of intelligence Lori Marino; 7. Universal biology: assessing universality from a single example Carlos Mariscal; 8. Equating culture, civilization, and moral development in imagining extraterrestrial intelligence: anthropocentric assumptions? John Traphagan; 9. Communicating with the other: infinity, geometry, and universal math and science Douglas Vakoch; Part III. Philosophical, Theological, and Moral Impact. How Do We Comprehend the Cultural Challenges Raised by Discovery?: Introduction; 10. Life, intelligence and the pursuit of value in cosmic evolution Mark Lupisella; 11. 'Klaatu barada nikto' - or, do they really think like us? Michael Ruse; 12. Alien minds Susan Schneider; 13. The moral subject of astrobiology: guideposts for exploring our ethical and political responsibilities towards extraterrestrial life Elspeth Wilson and Carol Cleland; 14. Astrobiology and theology Robin Lovin; 15. Would you baptize an extraterrestrial? Guy Consolmagno, SJ; Part IV. Practical Considerations: How Should Society Prepare for Discovery - and Non-Discovery?: Introduction; 16. Is there anything new about astrobiology and society? Jane Maienschein; 17. Evaluating preparedness for the discovery of extraterrestrial life: considering potential

  14. Ground source geothermal heat. Ground source heat pumps and underground thermal energy storage systems. Proceedings; Oberflaechennahe Geothermie. Erdgekoppelte Waermepumpen und unterirdische thermische Energiespeicher. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    At the ninth international user forum on shallow geothermal heat on 28th and 29th April, 2009, at BadStaffelstein (Federal Republic of Germany), the following lectures were held: (1) Information system on shallow geothermal heat for Bavaria (Marcellus Schulze); (2) Calculation of the spreading of temperature anomalies in groundwater as an instrument of planning of heat pump systems (Wolfgang Rauch); (3) Comparison of models for simulation of deep geothermal probes (Markus Proell); (4) Impact of the geometry of boreholes and probes on heat transport (Manfred Reuss); (5) Thermal respond tests and temperature depth profiles - Experience from research and practice (Markus Kuebert); (6) A model of simulation for the investigation of the impact of different heat transfer fluids on the efficiency of ground source heat pump devices (Roland Koenigsdorff); (7) The research project EWSplus - Investigations for quality assurance of geothermal probes (Mathieu Riegger); (8) Quality management of plants for the utilization of shallow geothermal heat with geothermal probes - the example of Baden-Wuerttemberg (Bruno Lorinser, Ingrid Stober); (9) Not every heat pump contributes to climate protection (Falk Auer); (10) Field measurements of heat pumps in residential buildings with modern standard and in older buildings (Marek Miara); (11) System technology for a great annual performance factor (Werner Schenk); (12) Modification of older geothermal heat probe devices for use with modern heat pumps (Klaus Friedrich Staerk); (13) Energy-efficient modernisation of a pensioners' condominium from the 1970s with solar-geothermal-air (Michael Guigas); (14) Evaluation and optimization of operation of seasonal storage systems in the foundations of office buildings (Herdis Kipry); (15) Evaluation of an innovative heating and cooling concept with rain water vessels, thermo-active building components and phase change materials in a residential building (Doreen Kalz); (16) Contracts for ground

  15. Vegetative filter strips efficiency controlling soil loss and trapping herbicides in two olive orchards at the short-term

    Science.gov (United States)

    de Luna, Elena; Guzmán, Gema; Gómez, José A.

    2014-05-01

    , G., Niehaus, E., Passeport, E., Payraudeau, S., Schäfera, R., Tournebize, J., & Schulz, R. (2011). Pesticide risk mitigation by vegetated treatment systems: a meta-analysis. Journal of Environmental Quality, 40: 1068-1080. Vianello, M., Vischetti, C., Scarponi, L., & Zanin, G. (2005). Herbicide losses in runoff events from a field with a low slope: role of a vegetative filter strip. Chemosphere, 61: 717-725. Withers, P. J. A., Hartikainen, H., Barberis, E., Flynn, N. J., & Warren, G. P. (2009). The effect of soil phosphorus on particulate phosphorus in land runoff. European Journal of Soil Science 60: 994-1004.

  16. The genera of Nematinae (Hymenoptera, Tenthredinidae

    Directory of Open Access Journals (Sweden)

    Marko Prous

    2014-10-01

    Full Text Available Recent phylogenetic studies on Nematinae based on DNA sequences have shown extensive incongruencies with current nomenclature of genus-group taxa. Here, we expand previous DNA sequence datasets based on three genes (CoI, Cytb, and EF-1α, to include a fourth (NaK and more genera. The analyses largely confirm the previous findings, particularly the existence of two well-supported large clades, Euura and Pristiphora, together comprising more than 75% of the species of Nematinae. Basal relationships within these two clades remain poorly resolved, mirroring the difficulties in delimiting genera based on morphology. In addition, a moderately supported small clade, Nematus, is found. The relationships between the Euura, Pristiphora, and Nematus clades are uncertain. Therefore, to stabilize the nomenclature we treat these clades as genera. This taxonomic treatment results in numerous new combinations of species names. The following synonymies are proposed for the available genus-group names. Synonyms of Euura Newman, 1837: Cryptocampus Hartig, 1837, Euura Agassiz, 1848, Pontania Costa, 1852, syn. n., Epitactus Förster, 1854, syn. n., Amauronematus Konow, 1890, syn. n., Holcocneme Konow, 1890, syn. n., Pachynematus Konow, 1890, syn. n., Holcocnema Schulz, 1906, syn. n., Holcocnemis Konow, 1907, syn. n., Pteronidea Rohwer, 1911, syn. n., Pontopristia Malaise, 1921, syn. n., Brachycoluma Strand, 1929, syn. n., Decanematus Malaise, 1931, syn. n., Pikonema Ross, 1937, syn. n., Phyllocolpa Benson, 1960, syn. n., Eitelius Kontuniemi, 1966, syn. n., Gemmura E.L. Smith, 1968, Eupontania Zinovjev, 1985, syn. n., Larinematus Zhelochovtsev, 1988, syn. n., Polynematus Zhelochovtsev, 1988, syn. n., Bacconematus Zhelochovtsev, 1988, syn. n., Alpinematus Lacourt, 1996, syn. n., Epicenematus Lacourt, 1998, syn. n., Kontuniemiana Lacourt, 1998, syn. n., Lindqvistia Lacourt, 1998, syn. n., Luea Wei and Nie, 1998, syn. n., and Tubpontania Vikberg, 2010, syn. n. Synonyms

  17. Clinical Observation on Thyroid Carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Park, Seon Yang; Shin, Yong Tae; Cho, Bo Yun; Kim, Byung Kuk; Koh, Chang Soon; Lee, Mun Ho [Seoul National University College of Medicine, Seoul (Korea, Republic of)

    1978-09-15

    Clinical features of 147 patients with biopsy-proven thyroid carcinomas were investigated from January, 1972 to April, 1978 at the Seoul National University Hospital with the following results. 1) The incidence of thyroid carcinomas according to their histopathological classification revealed 76.2% of papillary carcinoma, 19.0% of follicular carcinoma, and 3 cases of occult sclerozing carcinoma, 1 case of giant cell carcinoma and 1 case of metastatic melanoma. 2) The ratio of male to female patients was 1:8.3 and showed no difference between papillary and follicular carcinomas. 3) The age distribution showed the peak incidence in the fourth decade (29.3%) followed by the fifth and sixth decades. 4) The average duration of illness from the onset of symptoms was about 5 years while it was 4.4 years and 7.6 years in the papillary and follicular carcinomas respectively. 5) The diameter of the thyroid masses was smaller than 5 cm in 53.6% of the patients, from 5 cm to 10 cm in 40.0% and larger than 10 cm in 6.4%. 6) In 36.4% of the patients with thyroid carcinomas the thyroid masses were fixed to adjacent tissues. 7) Metastasis to the regional lymph nodes was noted in 40.0% of the total cases, and in 45.2% and 17.6% of the papillary and follicular carcinomas respectively, while the lung and bone metastases were found in 10.0% and 4.4% in each type respectively. 8) 88.9% of the patients showed cold areas in the thyroid scans using {sup 131}I. 9) Typical psammoma bodies were observed in 21.3% of the cases in the microscopic examination of the pathological specimens. 10) The initial diagnosis of thyroid malignancy could be made before histological confirmation in 64.5% of the patients. 11) The clinical staging slightly modified from Schulz method revealed 43.6% of the patients in stage I, 26.4% in stage II, 20.9% in stage III and 9.1% in stage IV. 12) The association with Hashimoto's thyroiditis was noted in 4 cases, with nodular goiter in 3 cases, and with follicular

  18. Health behaviour change interventions for couples: A systematic review.

    Science.gov (United States)

    Arden-Close, Emily; McGrath, Nuala

    2017-05-01

    Partners are a significant influence on individuals' health, and concordance in health behaviours increases over time in couples. Several theories suggest that couple-focused interventions for health behaviour change may therefore be more effective than individual interventions. A systematic review of health behaviour change interventions for couples was conducted. Systematic search methods identified randomized controlled trials (RCTs) and non-randomized interventions of health behaviour change for couples with at least one member at risk of a chronic physical illness, published from 1990-2014. We identified 14 studies, targeting the following health behaviours: cancer prevention (6), obesity (1), diet (2), smoking in pregnancy (2), physical activity (1) and multiple health behaviours (2). In four out of seven trials couple-focused interventions were more effective than usual care. Of four RCTs comparing a couple-focused intervention to an individual intervention, two found that the couple-focused intervention was more effective. The studies were heterogeneous, and included participants at risk of a variety of illnesses. In many cases the intervention was compared to usual care for an individual or an individual-focused intervention, which meant the impact of the couplebased content could not be isolated. Three arm studies could determine whether any added benefits of couple-focused interventions are due to adding the partner or specific content of couple-focused interventions. Statement of contribution What is already known on this subject? Health behaviours and health behaviour change are more often concordant across couples than between individuals in the general population. Couple-focused interventions for chronic conditions are more effective than individual interventions or usual care (Martire, Schulz, Helgeson, Small, & Saghafi, ). What does this study add? Identified studies targeted a variety of health behaviours, with few studies in any one area. Further

  19. Planetary Nomenclature: An Overview and Update for 2017

    Science.gov (United States)

    Gaither, Tenielle; Hayward, Rose; IAU Working GroupPlanetary System Nomenclature

    2017-10-01

    The task of naming planetary surface features, rings, and natural satellites is managed by the International Astronomical Union’s (IAU) Working Group for Planetary System Nomenclature (WGPSN). There are currently 15,361 IAU-approved surface feature names on 41 planetary bodies, including moons and asteroids. The members of the WGPSN and its task groups have worked since the early 1970s to provide a clear, unambiguous system of planetary nomenclature that represents cultures and countries from all regions of Earth. WGPSN members include Rita Schulz (Chair) and 9 other members representing countries around the globe. The participation of knowledgeable scientists and experts in this process is vital to its success of the IAU WGPSN . Planetary nomenclature is a tool used to uniquely identify features on the surfaces of planets or satellites so they can be located, described, and discussed in publications, including peer-review journals, maps and conference presentations. Approved names are listed in the Transactions of the IAU and on the Gazetteer of Planetary Nomenclature website. Any names currently in use that are not listed the Gazetteer are not official. Planetary names must adhere to rules and conventions established by the IAU WGPSN (see http://planetarynames.wr.usgs.gov/Page/Rules for the complete list). The gazetteer includes an online Name Request Form (http://planetarynames.wr.usgs.gov/FeatureNameRequest) that can be used by members of the professional science community. Name requests are first reviewed by one of six task groups (Mercury, Venus, Moon, Mars, Outer Solar System, and Small Bodies). After a task group has reviewed a proposal, it is submitted to the WGPSN. Allow four to six weeks for the review and approval process. Upon WGPSN approval, names are considered formally approved and it is then appropriate to use them in publications. Approved names are immediately entered into the database and shown on the website. Questions about the nomenclature

  20. THE BIOGRAPHY OF JÁNOS NAGYVÁTHY - THE FIRST HUNGARIAN AGRICULTURAL WRITER

    Directory of Open Access Journals (Sweden)

    Gábor LUKÁCS

    2002-03-01

    experience and the regularities regarding animals and plants discovered by the developing sciences. His main source is ’Elementa rei rusticae’ by Mitterpacher but he also mentioned 51 different books as sources, (34 of them in the section about plant cultivation. Plant cultivation had the same importance and number of pages as in the work of Mitterpacher but animal husbandry had twice as many pages. He wrote about the breeding of all farm animals but it was not the chapters on animal husbandry that pointed ahead but his remarks to help the rationalization of farming and the fact that he wrote about plant cultivation and animal husbandry as a whole. The book made him well-known in the country. He was offered the post of a land steward by Széchenyi Ferenc and Festetics György. Accepting the latter he moved to Keszthely and he took over the management of the domain of 162ooo acres. The earl left the army at that time and started to restore his neglected domain. Nagyváthy’s main task was to improve farm management. He introduced strict accountancy and applied double-entry book-keeping for the first time and Hungary and his main principle was to put down all farming activities in writing. The farm managers were not suitable for this task so he convinced Festetics to found a school for them and an other secondary grammar school in the other centre of the domain in Csurgó. By 1797 the condition of the domain improved significantly and the Earl founded ’Georgikon’ the first agricultural college in Europe though without the land steward who favoured the idea of enlightment (the court in Vienna would not approve it. After the expiration of his contract he retired and moved to Csurgó, where he inspected the secondary grammar school as a secular inspector. He spent the last 22 years of his life here ’hard working in respectable poverty’. He died on 13th February 1819 (according to other sources on 24th. His posthumous books are as follows: ’Hungarian housewife on the farm