WorldWideScience

Sample records for scholarship review series

  1. Discussing legal scholarship from political science perspectives : Review

    NARCIS (Netherlands)

    Edwards, P.; Giessen, L.

    2014-01-01

    Scholarship in international law aims at addressing global forest governance comprehensively. This article reviews the recent contribution Global Forest Governance — Legal Concepts and Policy Trends by Rowena Maguire and puts it into the perspective of recent political and policy science research on

  2. Expanding Group Peer Review: A Proposal for Medical Education Scholarship.

    Science.gov (United States)

    Dumenco, Luba; Engle, Deborah L; Goodell, Kristen; Nagler, Alisa; Ovitsh, Robin K; Whicker, Shari A

    2017-02-01

    After participating in a group peer-review exercise at a workshop presented by Academic Medicine and MedEdPORTAL editors at the 2015 Association of American Medical Colleges Medical Education Meeting, the authors realized that the way their work group reviewed a manuscript was very different from the way by which they each would have reviewed the paper as an individual. Further, the group peer-review process yielded more robust feedback for the manuscript's authors than did the traditional individual peer-review process. This realization motivated the authors to reconvene and collaborate to write this Commentary to share their experience and propose the expanded use of group peer review in medical education scholarship.The authors consider the benefits of a peer-review process for reviewers, including learning how to improve their own manuscripts. They suggest that the benefits of a team review model may be similar to those of teamwork and team-based learning in medicine and medical education. They call for research to investigate this, to provide evidence to support group review, and to determine whether specific paper types would benefit most from team review (e.g., particularly complex manuscripts, those receiving widely disparate initial individual reviews). In addition, the authors propose ways in which a team-based approach to peer review could be expanded by journals and institutions. They believe that exploring the use of group peer review potentially could create a new methodology for skill development in research and scholarly writing and could enhance the quality of medical education scholarship.

  3. Unpacking MOOC Scholarly Discourse: A Review of Nascent MOOC Scholarship

    Science.gov (United States)

    Ebben, Maureen; Murphy, Julien S.

    2014-01-01

    The rapid rise of MOOCs (Massive Open Online Courses) signals a shift in the ways in which digital teaching and learning are engaged in and understood. Drawing upon a comprehensive search of nine leading academic databases, this paper examines the initial phase of MOOC scholarship (2009-2013), and offers an analysis of these empirical studies that…

  4. Applying Bakhtin Scholarship on Discourse in Education: A Critical Review Essay

    Science.gov (United States)

    Matusov, Eugene

    2007-01-01

    Recently, Bakhtinian philologists have charged scholars of education with misapplying Bakhtin's scholarship in their field. In this critical essay, Eugene Matusov reviews two recent edited collections relevant to this issue: Arnetha F. Ball and Sarah Warshauer Freedman's Bakhtinian Perspectives on Language, Literacy, and Learning and Bonny Norton…

  5. Evaluating Prior Scholarship in Literature Reviews of Research Articles: A Comparative Study of Practices in Two Research Paradigms

    Science.gov (United States)

    Kwan, Becky S. C.; Chan, Hang; Lam, Colin

    2012-01-01

    Evaluations of prior scholarship play a crucial role in the literature review (LR) of a research article by showing how the boundary of an area of inquiry can be further advanced by the writer's work. Yet, many inexperienced writers find evaluating others' work a major challenge. Although the task has received some attention in research and…

  6. Communicating New Library Roles to Enable Digital Scholarship: A Review Article

    Science.gov (United States)

    Cox, John

    2016-01-01

    Academic libraries enable a wide range of digital scholarship activities, increasingly as a partner rather than as a service provider. Communicating that shift in role is challenging, not least as digital scholarship is a new field with many players whose activities on campus can be disjointed. The library's actual and potential contributions need…

  7. A review of subsequence time series clustering.

    Science.gov (United States)

    Zolhavarieh, Seyedjamal; Aghabozorgi, Saeed; Teh, Ying Wah

    2014-01-01

    Clustering of subsequence time series remains an open issue in time series clustering. Subsequence time series clustering is used in different fields, such as e-commerce, outlier detection, speech recognition, biological systems, DNA recognition, and text mining. One of the useful fields in the domain of subsequence time series clustering is pattern recognition. To improve this field, a sequence of time series data is used. This paper reviews some definitions and backgrounds related to subsequence time series clustering. The categorization of the literature reviews is divided into three groups: preproof, interproof, and postproof period. Moreover, various state-of-the-art approaches in performing subsequence time series clustering are discussed under each of the following categories. The strengths and weaknesses of the employed methods are evaluated as potential issues for future studies.

  8. A Review of Subsequence Time Series Clustering

    Science.gov (United States)

    Teh, Ying Wah

    2014-01-01

    Clustering of subsequence time series remains an open issue in time series clustering. Subsequence time series clustering is used in different fields, such as e-commerce, outlier detection, speech recognition, biological systems, DNA recognition, and text mining. One of the useful fields in the domain of subsequence time series clustering is pattern recognition. To improve this field, a sequence of time series data is used. This paper reviews some definitions and backgrounds related to subsequence time series clustering. The categorization of the literature reviews is divided into three groups: preproof, interproof, and postproof period. Moreover, various state-of-the-art approaches in performing subsequence time series clustering are discussed under each of the following categories. The strengths and weaknesses of the employed methods are evaluated as potential issues for future studies. PMID:25140332

  9. The overview of reviews: unique challenges and opportunities when research syntheses are the principal elements of new integrative scholarship.

    Science.gov (United States)

    Cooper, Harris; Koenka, Alison C

    2012-09-01

    In the past two decades, a new form of scholarship has appeared in which researchers present an overview of previously conducted research syntheses on the same topic. In these efforts, research syntheses are the principal units of evidence. Overviews of reviews introduce unique problems that require unique solutions. This article describes what methods overviewers have developed or have adopted from other forms of scholarship. These methods concern how to (a) define the broader problem space of an overview, (b) conduct literature searches that specifically look for research syntheses, (c) address the overlap in evidence in related reviews, (d) evaluate the quality of both primary research and research syntheses, (e) integrate the outcomes of research syntheses, especially when they produce discordant results, (f) conduct a second-order meta-analysis, and (g) present findings. The limitations of overviews are also discussed, especially with regard to the age of the included evidence. (PsycINFO Database Record (c) 2012 APA, all rights reserved).

  10. A Review of the Literature on the Scholarship Program for College Students in China

    OpenAIRE

    王, 帥

    2013-01-01

    Owing to higher education expansion worldwide, scholarship program for college students become a great concern in the society. Although the national financial support system has been established, the system is far from being perfect and little empirical studies conducted by researchers. The purpose of this study is to survey researches of the scholarship program for college students in China and to clarify the findings and problems of studies.

  11. Review of the Umthombo Youth Development Foundation scholarship scheme, 1999–2013

    Science.gov (United States)

    MacGregor, Gavin; Campbell, Laura

    2015-01-01

    Introduction Staffing of rural and remote facilities is a challenge throughout the world. Umthombo Youth Development Foundation (UYDF) has been running a rurally based scholarship scheme since 1999. The aim of this review is to present data on the number of students selected, their progress, graduation and work placement from inception of the scheme until 2013. Methods Data were extracted from the UYDF data base using a data collection template to ensure all important information was captured. Results Since 1999, 430 rural students across 15 health disciplines have been supported by UYDF. The annual pass rate has been greater than 89%, and less than 10% of students have been excluded from university. All graduates have spent time working in rural areas (excluding the 32 currently doing internships) and 72% (52/73) of those with no work-back obligation continue to work in rural areas. Discussion and conclusion The UYDF model is built around local selection, compulsory academic and peer mentoring and social support, comprehensive financial support and experiential holiday work. The results are encouraging and highlight the fact that rural students can succeed at university and will come back and work in rural areas. With 46% of the South African population situated rurally, greater thought and effort must be put into the recruitment and training of rural scholars as a possible solution to the staffing of rural healthcare facilities. The UYDF provides a model which could be replicated in other parts of South Africa. PMID:26245594

  12. Review article: leading the future: guiding two predominant paradigm shifts in medical education through scholarship.

    Science.gov (United States)

    Naik, Viren N; Wong, Anne K; Hamstra, Stanley J

    2012-02-01

    The purpose of this article is to consolidate some of the key concepts about scholarship in education related to the specialty of anesthesiology. We frame the discussion on two paradigm shifts in medical education, i.e., competency-based education and lifelong learning, and the scholarly approaches to lead these paradigm shifts in anesthesiology. Conventional medical education is being challenged by a shift from time-based education to competency-based education. This potential shift will also create a continuous need to foster a culture of lifelong learning in contrast with the traditional compartmentalized model of undergraduate, postgraduate, and continuing medical education. The specialty of anesthesia has the capacity to lead these changes by enhancing scholarship in education locally and nationally. The promotion of scholarship in education necessitates the creation of infrastructure and accountability frameworks to show return on investment. High-quality scholarship in medical education requires a solid rationale and, ultimately, a demonstrable benefit to patient care. Accountability of lifelong learning to established competency frameworks seems inevitable. Anesthesiology is one of only a few specialties that can truly protect faculty from clinical responsibilities in favour of scholarship pursuits. With appropriate support for scholarship in education, anesthesiologists have an opportunity to lead these paradigm shifts.

  13. Review of the Umthombo Youth Development Foundation scholarship scheme, 1999–2013

    Directory of Open Access Journals (Sweden)

    Andrew Ross

    2015-02-01

    Full Text Available Introduction: Staffing of rural and remote facilities is a challenge throughout the world. Umthombo Youth Development Foundation (UYDF has been running a rurally based scholarship scheme since 1999.The aim of this review is to present data on the number of students selected, their progress, graduation and work placement from inception of the scheme until 2013.Methods: Data were extracted from the UYDF data base using a data collection template to ensure all important information was captured.Results: Since 1999, 430 rural students across 15 health disciplines have been supported by UYDF. The annual pass rate has been greater than 89%, and less than 10% of students have been excluded from university. All graduates have spent time working in rural areas (excluding the 32 currently doing internships and 72% (52/73 of those with no work-back obligation continue to work in rural areas.Discussion and conclusion: The UYDF model is built around local selection, compulsory academic and peer mentoring and social support, comprehensive financial support and experiential holiday work. The results are encouraging and highlight the fact that rural students can succeed at university and will come back and work in rural areas. With 46% of the South African population situated rurally, greater thought and effort must be put into the recruitment and training of rural scholars as a possible solution to the staffing of rural healthcare facilities. The UYDF provides a model which could be replicated in other parts of South Africa.

  14. Review of the Umthombo Youth Development Foundation scholarship scheme, 1999-2013.

    Science.gov (United States)

    Ross, Andrew; MacGregor, Gavin; Campbell, Laura

    2015-03-31

    Staffing of rural and remote facilities is a challenge throughout the world. Umthombo Youth Development Foundation (UYDF) has been running a rurally based scholarship scheme since 1999.The aim of this review is to present data on the number of students selected, their progress, graduation and work placement from inception of the scheme until 2013. Data were extracted from the UYDF data base using a data collection template to ensure all important information was captured. Since 1999, 430 rural students across 15 health disciplines have been supported by UYDF. The annual pass rate has been greater than 89%, and less than 10% of students have been excluded from university. All graduates have spent time working in rural areas (excluding the 32 currently doing internships) and 72% (52/73) of those with no work-back obligation continue to work in rural areas. The UYDF model is built around local selection, compulsory academic and peer mentoring and social support, comprehensive financial support and experiential holiday work. The results are encouraging and highlight the fact that rural students can succeed at university and will come back and work in rural areas. With 46% of the South African population situated rurally, greater thought and effort must be put into the recruitment and training of rural scholars as a possible solution to the staffing of rural healthcare facilities. The UYDF provides a model which could be replicated in other parts of South Africa.

  15. 75 FR 57086 - Submission for Review: Federal Cyber Service: Scholarship for Service (SFS) Registration Web Site

    Science.gov (United States)

    2010-09-17

    ... number of qualified students entering the fields of information assurance and computer security in an... information assurance field. Participating students who receive scholarships from this program are required to... other Federal agencies the opportunity to comment on an existing information collection request (ICR...

  16. CES4Health.info: A Web-Based Mechanism for Disseminating Peer-Reviewed Products of Community-Engaged Scholarship--Reflections on Year One

    Science.gov (United States)

    Jordan, Catherine; Gelmon, Sherril; Ryan, Katharine; Seifer, Sarena D.

    2012-01-01

    CES4Health.info was launched in November 2009 as an online mechanism for peer reviewing and disseminating products of community-engaged scholarship in forms other than journal articles. One year after its launch, the authors conducted an online survey of CES4Health.info contributing authors, reviewers, and users of published products. Early…

  17. Perspective: Recognizing and rewarding clinical scholarship.

    Science.gov (United States)

    Grigsby, R Kevin; Thorndyke, Luanne

    2011-01-01

    Faculty members in medical schools and academic medical centers are in a constant process of generating new knowledge. The cornerstone of academia--and academic medicine--is scholarship. Traditionally, tenure and/or academic promotion in the professorial ranks is awarded to those who meet institutional criteria in the missions of research, teaching, and service, including patient care. In the academic review process, priority is often placed on a record of demonstrated, consistent success in traditional laboratory research, also known as the scholarship of discovery. More recently, there has been greater recognition of other forms of scholarship: education, application, and integration. These forms of scholarship, although less recognized, also result in the generation of new knowledge. In an attempt to understand the breadth and scope of clinical scholarship, the authors searched the extant literature in academic medicine for a definition of clinical scholarship and expanded the search to disciplines outside of medicine. They found that succinct, discrete definitions of clinical scholarship have been published in other disciplines, but not in academic medicine. After reviewing definitions of clinical scholarship from other disciplines, adapting definitions of educational scholarship in academic medicine, and including qualities unique to clinical scholarship, the authors developed a framework for understanding clinical scholarship in academic medicine as a means for opening a dialogue within the academic medical community. This dialogue hopefully will lead to formulating a succinct, discrete definition of clinical scholarship that will allow greater recognition and reward for clinical scholars in the promotion and tenure process.

  18. Pseudocirrhosis: A Case Series and Literature Review

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    Abimbola Adike

    2016-07-01

    Full Text Available Pseudocirrhosis describes morphological changes of the liver that closely mimic cirrhosis, without the typical histopathological changes seen in cirrhosis. It most commonly occurs in patients with metastatic breast cancer, although it has been reported in other malignancies as well. Like in cirrhosis, portal hypertension is often seen in patients with pseudocirrhosis. Pseudocirrhosis is a rare but important complication of metastatic cancer. In this case series and literature review, we describe 6 patients with hormone-receptor-positive metastatic breast cancer. We report the significant morbidity associated with pseudocirrhosis in the course of treatment in patients with metastatic breast cancer.

  19. Ictal swearing: a case series and review.

    Science.gov (United States)

    Birca, Veronica; Tayah, Tania; Saint-Hilaire, Jean-Marc; Nguyen, Dang Khoa

    2013-12-01

    Seizures can manifest with ictal swearing but few studies have investigated the localising value of this epileptic manifestation. In this case series and review of the literature, we attempted to determine whether ictal swearing could help localise the epileptic focus. We review two previously published cases and report eight additional epileptic patients with ictal swearing for whom the epileptic focus was determined based on clinical, structural, electrophysiological, and surgical outcome data. Results indicated that ictal swearing occurs more commonly in male subjects and lateralises to the non-dominant hemisphere, but has poor localisation value, arising either from the frontal, parietal, temporal or occipital lobes in different patients. We discuss the significance of these findings. [Published with video sequences].

  20. New Indices in Scholarship Assessment

    Science.gov (United States)

    Callen, Erin C.; Nahata, Milap C.

    2009-01-01

    Faculty members' contributions to research and scholarship are measured by a variety of indices. Assessment also has become an integral part of the Accreditation Council for Pharmacy Education's accreditation process for professional programs. This review describes some of the newer indices available for faculty scholarship assessment. Recently described metrics include the h-index, m-quotient, g-index, h(2) index, a-index, m-index, r-index, ar index, and the creativity index. Of the newer scholarship metrics available, the h-index and m-quotient will likely have the most widespread application in the near future. However, there is no substitute for thoughtful peer review by experienced academicians as the primary method of research and scholarship assessment. PMID:19885080

  1. A Review and Evaluation of the Illinois State Library Scholarship Program, 1961-1980. Report No. 7.

    Science.gov (United States)

    Drone, Jeanette M.

    From 1961-1980, the Illinois State Library (ISL) awarded scholarships using Library Services Act (LSA) and Library Services and Construction Act (LSCA) funds. The purpose was to recruit talented college graduates to the library profession and to retain these individuals in Illinois libraries. Of the 212 individuals who received scholarships, 198…

  2. Redefining Scholarship: The Boyer Model

    OpenAIRE

    Steve Urban

    2017-01-01

    The Boyer classification provides a good method for documenting the scholarly activity of academic physicians.  His types of scholarship include the scholarship of discovery, the scholarship of integration, the scholarship of application, and the scholarship of teaching.

  3. WWC Review of the Report "The Short-Term Effects of the Kalamazoo Promise Scholarship on Student Outcomes." What Works Clearinghouse Single Study Review

    Science.gov (United States)

    What Works Clearinghouse, 2014

    2014-01-01

    Researchers examined the impacts of the Kalamazoo Promise Scholarship program on academic and behavioral outcomes of students in grades 9-12 in Kalamazoo Public Schools (KPS). The Kalamazoo Promise Scholarship program offers college scholarships to graduating high school students in the KPS district. The percentage of tuition and fees covered is…

  4. AWG Scholarships

    Science.gov (United States)

    The Association for Women Geoscientists will give two Chrysalis Scholarships in 1990. The awards are for women who returned to school after an interruption in education of at least a year and who are finishing a thesis for a Masters or Ph.D. degree in geoscience.1989 was the first year for the Chrysalis. The recipient, Diane Bellis, was a doctoral candidate in geochemistry at New Mexico Institute of Mining and Technology in Socorro and the mother of four. She received her Ph.D. in May and is currently an AAAS Fellow in the Department of State in Washington, D.C., working on U.S. science policy in Africa and Latin America.

  5. Acute paediatric paraplegia: a case series review.

    Science.gov (United States)

    Sharpe, Abigail N; Forsyth, Rob

    2013-11-01

    Paediatric paraplegia resulting from spinal cord pathology of any cause is rare; hence prognostic information for children less than 16 years is limited. This case series review aims to ascertain all cases of paediatric paraplegia from 1997 to 2012 in the former Northern Region of England. Children presenting with sudden paraplegia before the age of 16 years were multiply ascertained from databases in the regional paediatric neurology, neuroradiology, neuro-oncology and adult spinal injuries units. Data were obtained from retrospective case note review. A total of 44 cases (24 female) were identified. The incidence is estimated at 0.49 per 100,000 children under 16/year (95% confidence interval 0.41-0.57). Mean age of onset was 8.8 years and the most common aetiology was inflammatory. Twelve months post presentation, mortality was zero and a good outcome (defined as Gross Motor Function Classification System grades I or II) was seen in 66.6%. Motor outcome at 12 months was associated with the presence of bladder/bowel signs at presentation, previous viral illness and initial severity of paraplegia. Bladder signs at presentation were the strongest predictor of prognosis (OR for poor motor outcome 10.3). We were unable to demonstrate a relationship between aetiology and late outcome. Paediatric paraplegia is rare. Mortality rates are low and 66.6% have a good outcome with fully or nearly independent walking. Bladder signs are the strongest predictor of prognosis. Copyright © 2013 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  6. Student Voice in Work Integrated Learning Scholarship: A Review of Teacher Education and Geographical Sciences

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    Kate Eileen Thomson

    2017-03-01

    Full Text Available Work integrated learning is an umbrella term that refers to the opportunities provided to university students to integrate knowledge of theory and practice as part of their degree program. As the role of students in higher education is evolving, we sought to develop our understanding of the role of students in the work integrated learning (WIL space through exploring current literature on student voice. In this paper, we consider what has been reported about WIL in relation to student voice, how it has been represented, and how this has influenced practice. We undertook a systematic literature review for two different disciplines, one which represented an example of a professionally accredited undergraduate degree program (teacher education, and the other an example of a program with no professional accreditation (geographical sciences. The teacher education literature demonstrated more clearly the use of student voice to inform WIL within curriculum design. However, the geographical sciences literature did include examples of student voice being incorporated within the design of collaborative community-based forms of WIL. A role for students as researchers, who lead research and initiate curriculum change into WIL, was noticeably absent in both disciplinary sets of literature. The lack of evidence of the inclusion of students in the design, conduct, and analysis of WIL provides an invitation for SoTL scholars to redefine the role of students in this space.

  7. Minority engineering scholarships, 2012.

    Science.gov (United States)

    2014-02-01

    Scholarships for Minority Students Studying Engineering and Science: Support will make scholarships available to minority students : interested in engineering and science and will increase significantly the number of minority students that Missouri S...

  8. Review of "The Effect of Special Education Vouchers on Public School Achievement: Evidence from Florida's McKay Scholarship Program"

    Science.gov (United States)

    Yun, John T.

    2008-01-01

    A new report published by the Manhattan Institute for Education Policy, "The Effect of Special Education Vouchers on Public School Achievement: Evidence from Florida's McKay Scholarship Program," attempts to examine the complex issue of how competition introduced through school vouchers affects student outcomes in public schools. The…

  9. 78 FR 26664 - Submission for Review: CyberCorps®: Scholarship For Service (SFS) Registration Web Site

    Science.gov (United States)

    2013-05-07

    ... students entering the fields of information assurance and computer security in an effort to respond to the...-year colleges and universities scholarship grants to attract students to the information assurance... Federal agencies the opportunity to comment on an existing information collection request (ICR) 3206-0246...

  10. INTRODUCTION: GRADUATE STUDENT SCHOLARSHIP

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    Laverne Jacobs

    2015-02-01

    Full Text Available The Windsor Yearbook of Access to Justice is proud to publish issue 32 (1. This issue features a special section highlighting the scholarship of graduate students. While it is always a pleasure to read promising work by newer scholars in the fields of law and social justice, we are certain that this collection of articles represents some of the finest and thought-provoking scholarship stemming from current graduate students in law. The articles stem from a graduate student essay contest that WYAJ held in 2013 and for which we received many submissions. The collection of selected papers offers a view of legal and interdisciplinary research examining issues that are topically diverse but which are all of deep, long-term importance to the world of access to justice. A reader of the special section on Graduate Student Scholarship will find explorations of access to justice from the perspectives of equality rights, discretion, adjudication and methods of legal service delivery, to name a few. A prize was offered to two papers judged to be of exceptional quality. I am very pleased to announce that the winners of those two prizes are Andrew Pilliar, for his article “Exploring a Law Firm Business Model to Improve Access to Justice” and Blair A. Major, for his contribution, “Religion and Law in R v NS: Finding Space to Re-think the Balancing Analysis”. The Editorial Board thanks all those who submitted papers to the contest and to this final special issue of the Windsor Yearbook of Access to Justice. Another notable feature of this issue is the introduction of a section called Research Notes. The Yearbook will periodically publish peer-reviewed research notes that present the findings of empirical (quantitative, qualitative or mixed method research studies. This section aims to contribute to the growing and important body of empirical scholarship within the realm of access to justice socio-legal research. We hope that you enjoy

  11. CES4Health.info: an online tool for peer reviewed publication and dissemination of diverse products of community-engaged scholarship.

    Science.gov (United States)

    Jordan, Catherine; Seifer, Sarena D; Gelmon, Sherril B; Ryan, Katharine; McGinley, Piper

    2011-01-01

    Community-engaged scholarship (CES)-research, teaching, programmatic and other scholarly activities conducted through partnerships between academic and community partners-may result in innovative applied products such as manuals, policy briefs, curricula, videos, toolkits, and websites. Without accepted mechanisms for peer-reviewed publication and dissemination, these products often do not "count" toward faculty promotion and tenure (P&T) and have limited opportunities for broad impact. This paper reports on CES4Health.info, a unique online tool for peer-reviewed publication and dissemination of products of CES in forms other than journal articles. In its first year, CES4Health.info has published 24 products and documented the satisfaction of users, authors, and reviewers.

  12. [Cold urticaria: case series and literature review].

    Science.gov (United States)

    Sánchez, Jorge Mario; Ramírez, Ruth Helena; Tamayo, Liliana María; Chinchilla, Carlos Fernando; Cardona, Ricardo

    2011-06-01

    Cold urticaria is one of the five most common causes of chronic urticaria and is grouped as a physical urticaria. It can occur after exposure to cold, either through solid objects, air or liquids. Patients may have symptoms of urticaria, angioedema, respiratory distress and even anaphylaxis when the skin is exposed to a cold environment, such as handling refrigerated objects, swimming in cold water or entering an air-conditioned room. Five cases of cold urticaria are presented, followed by a brief literature review.

  13. Canadian Research Librarians have Little Time for Scholarship. A review of: Fox, David. “Finding Time for Scholarship: A Survey of Canadian Research University Librarians.” Portal: Libraries and the Academy 7.4 (2007: 451-62.

    Directory of Open Access Journals (Sweden)

    Pamela Haley

    2008-06-01

    Full Text Available Objective – To provide comparative data from Canadian research universities regarding the time spent on scholarly activities by research librarians.Design – Qualitative study employing a bilingual survey consisting of thirty-nine questions. Setting – Canadian Association of Research Libraries (CARL located at the twenty-seven CARL universities during the spring and fall of 2006.Subjects – CARL university librarians for whom e-mail addresses could be retrieved.Methods – The survey was distributed to 1052 CARL librarians during the spring and fall of 2006 via e-mail. Problems with the clarity of two questions became evident during the receipt of responses. The questions were revised and resubmitted to the same population.Main Results – Five hundred and twenty responses (49.4% were received, with 441 (84.8% in English and 15.2% in French. A total of 53 surveys were unusable, leaving 467 (44.4% cases as the basis for data analysis. Responses to the survey revealed that 51.4% of participants were required or encouraged to undertake scholarship. Ofthese, 35% were expected, in addition to sabbatical and study leaves, to make scholarship an integral and ongoing part of their professional responsibilities. Due to the individualized and subjective nature of the responses, no clear data emerged on the balance between scholarship and other professional activities. The majority of research librarians, on average, spent less than five hours per week on scholarship activities. For the 290 full-time librarians surveyed, the average time spent per week on all activities (professional and scholarly was 47.4 hours. Almost one third of the full time librarians worked fifty hours or more per week – the equivalent to the time commitment of the average university professor. Participants indicated that in an ideal world they would like to spend 10% less time on assigned duties. Francophone respondents spent 5% more of their time on professional

  14. Prediction of Long-Memory Time Series: A Tutorial Review

    Science.gov (United States)

    Bhansali, R. J.; Kokoszka, P. S.

    Two different approaches, called Type-I and Type-II, to linear least-squares prediction of a long-memory time series are distinguished. In the former, no new theory is required and a long-memory time series is treated on par with a standard short-memory time series and its multistep predictions are obtained by using the existing modelling approaches to prediction of such time series. The latter, by contrast, seeks to model the long-memory stochastic characteristics of the observed time series by a fractional process such that its dth fractional difference, 0 memory process. The various approaches to constructing long-memory stochastic models are reviewed, and the associated question of parameter estimation for these models is discussed. Having fitted a long-memory stochastic model to a time series, linear multi-step forecasts of its future values are constructed from the model itself. The question of how to evaluate the multistep prediction constants is considered and three different methods proposed for doing so are outlined; it is further noted that, under appropriate regularity conditions, these methods apply also to the class of linear long memory processes with infinite variance. In addition, a brief review of the class of non-linear chaotic maps implying long-memory is given.

  15. The future of electronic scholarship

    Directory of Open Access Journals (Sweden)

    Cornelius Holtorf

    2004-01-01

    Full Text Available This paper about the future of electronic scholarship takes the form of a commentary about my experiences with publishing an electronic monograph. An earlier version of that work was originally submitted to the University of Wales as a hypermedia Doctoral dissertation in archaeology. I will discuss to what extent (if any the electronic and multilinear format of my work proved valuable in challenging and advancing some foundations of current academic discourse. A key question is how academic credibility can be maintained, while at the same time pioneering some radical possibilities of electronic scholarship. It emerges that the criteria for this credibility are themselves at stake. The paper is divided into three main parts. After a short introduction , I will first review three ways in which I originally thought that the hypermedia format would allow clear benefits for academic writing and discourse, and how I see them now. They refer to intertextuality, the open-ended 'living' text, and multilinearity in writing and argument. Then I will review the main problems which I originally thought might be difficult to reconcile with contemporary academic discourse, and discuss to what extent they indeed turned out to be obstacles. These include screen reading, orientation and navigation issues, and the problem of long-term preservation. Finally, I will turn to the issue of academic publishing and how electronic scholarship may be able to help it become more satisfactory by dissolving existing ties to commercial interests.

  16. Education scholarship in emergency medicine part 1: innovating and improving teaching and learning.

    Science.gov (United States)

    Sherbino, Jonathan; Van Melle, Elaine; Bandiera, Glen; McEwen, Jill; Leblanc, Constance; Bhanji, Farhan; Frank, Jason R; Regehr, Glenn; Snell, Linda

    2014-05-01

    As emergency medicine (EM) education evolves, a more advanced understanding of education scholarship is required. This article is the first in a series of three articles that reports the recommendations of the 2013 education scholarship consensus conference of the Academic Section of the Canadian Association of Emergency Physicians. Adopting the Canadian Association for Medical Education's definition, education scholarship (including both research and innovation) is defined. A rationale for why education scholarship should be a priority for EM is discussed.

  17. Maxillary double lip: A case series with review of literature

    Directory of Open Access Journals (Sweden)

    Vela D Desai

    2015-01-01

    Full Text Available Double lip is a rare dental anomaly affecting either upper or lower lip or concurrently. It may be congenital or acquired. This deformity can affect the facial esthetics as it gets exaggerated while speaking, smiling, or chewing food. When it interferes with speech, double lip may cause potential functional problems. The purpose of this article is to review the literature on double lip and present a case series of maxillary double lip.

  18. Creating Digital Scholarship Services at Appalachian State University

    Science.gov (United States)

    Mitchem, Pamela Price; Rice, Dea Miller

    2017-01-01

    This article reviews literature related to building digital scholarship centers and explores the experience of Appalachian State University Libraries in planning and implementing a digital scholarship program. Appalachian surveyed its faculty, performed a gap analysis of existing services, compared programs at other universities, and inventoried…

  19. A Journal-Neutral Ratio for Marketing Faculty Scholarship Assessment

    Science.gov (United States)

    Elbeck, Matt; Baruca, Arne

    2015-01-01

    This article proposes a journal-neutral Publication to Citation Ratio (PCR) to complement qualitative methods to evaluate a marketing educator's scholarship for reappointment, promotion, tenure, and post-tenure review (RPTP) decisions. We empirically establish a minimum time period to evaluate scholarship data, then benchmark publication and…

  20. A Scrutiny of the Coaching Education Program Scholarship since 1995

    Science.gov (United States)

    McCullick, Bryan; Schempp, Paul; Mason, Ilse; Foo, Cornell; Vickers, Brad; Connolly, Graeme

    2009-01-01

    The authors sought to identify and categorize completed coaching education program (CEP) scholarship published in a recent 13-year period to provide a framework regarding the process of how coaches are prepared and certified. Scholarship was defined as data-based investigations, reviews, and position papers focused on CEPs, coaching training, and…

  1. Strength-Based Scholarship and Good Education: The Scholarship Circle

    Science.gov (United States)

    Fung, Dilly

    2017-01-01

    In an era in which "teaching excellence" in higher education attracts much attention, what is "scholarship?" In this conceptual paper, I re-examine the notion of scholarship in relation to the goals and purposes of higher education. How does "scholarship" speak to value-based conceptions of "good" education…

  2. Valla on Biblical Scholarship

    DEFF Research Database (Denmark)

    Haan, Annet den

    2016-01-01

    Lorenzo Valla’s Annotationes to the New Testament have been the object of study both as part of the history of Biblical scholarship and in the context of Valla’s own intellectual development. The work was, however, embedded in the intellectual context of the Vatican court in the 1450s, where...... several humanists were engaged in Biblical scholarship. A comparison of Valla’s approach to the Bible with that of Cardinal Bessarion, George of Trebizond, and Giannozzo Manetti shows that these authors shared a set of principles which they debated among themselves and applied each in their own way....

  3. Minority engineering scholarships renewal, 2011.

    Science.gov (United States)

    2012-08-01

    Scholarships for Minority Students Studying Engineering and Science : Support will make scholarships available to minority students : interested in engineering and science and will increase significantly the number of minority students that Missouri ...

  4. A meaningful MESS (Medical Education Scholarship Support).

    Science.gov (United States)

    Whicker, Shari A; Engle, Deborah L; Chudgar, Saumil; DeMeo, Stephen; Bean, Sarah M; Narayan, Aditee P; Grochowski, Colleen O'Connor; Nagler, Alisa

    2016-01-01

    Graduate medical education faculty bear the responsibility of demonstrating active research and scholarship; however, faculty who choose education-focused careers may face unique obstacles related to the lack of promotion tracks, funding, career options, and research opportunities. Our objective was to address education research and scholarship barriers by providing a collaborative peer-mentoring environment and improve the production of research and scholarly outputs. We describe a Medical Education Scholarship Support (MESS) group created in 2013. MESS is an interprofessional, multidisciplinary peer-mentoring education research community that now spans multiple institutions. This group meets monthly to address education research and scholarship challenges. Through this process, we develop new knowledge, research, and scholarly products, in addition to meaningful collaborations. MESS originated with eight founding members, all of whom still actively participate. MESS has proven to be a sustainable unfunded local community of practice, encouraging faculty to pursue health professions education (HPE) careers and fostering scholarship. We have met our original objectives that involved maintaining 100% participant retention; developing increased knowledge in at least seven content areas; and contributing to the development of 13 peer-reviewed publications, eight professional presentations, one Masters of Education project, and one educational curriculum. The number of individuals engaged in HPE research continues to rise. The MESS model could be adapted for use at other institutions, thereby reducing barriers HPE researchers face, providing an effective framework for trainees interested in education-focused careers, and having a broader impact on the education research landscape.

  5. Building Educational Scholarship: A Roadmap for Success

    Science.gov (United States)

    Goldman, Ellen F.; Hamburger, Ellen K.; Ottolini, Mary C.

    2014-01-01

    In this paper, we describe the faculty development resources, structures, and processes utilized to promote educational scholarship in a department of pediatrics. We discuss a 5-year effort based on the strategy of forming an "academy" of educational scholars and resulting in significant increases in peer-reviewed conference…

  6. A Decade of Scholarship in Marketing Education

    Science.gov (United States)

    Abernethy, Avery M.; Padgett, Daniel

    2011-01-01

    The teaching environment in business schools has changed dramatically over the last decade. But the last comprehensive review of the scholarship of teaching was conducted more than a decade ago. Where and from whom do the best practices for teaching originate today? To answer this question, the authors examine marketing education scholarship…

  7. Community-Engaged Scholarship

    DEFF Research Database (Denmark)

    Barinaga, Ester; Parker, Patricia S.

    2013-01-01

    We are pleased to offer this special issue on community-engaged scholarship. As scholar-activists working for social justice alongside youth of color (Pat) and critical arts activists engaging with stigmatized communities (Ester), we began this project with the intent of gathering a collection...

  8. Assessing Culturally Competent Scholarship.

    Science.gov (United States)

    Mendias, Elnora P.; Guevara, Edilma B.

    2001-01-01

    Eight criteria for culturally competent scholarship (contextuality, relevance, communication styles, awareness of identity and power differences, disclosure, reciprocation, empowerment, time) were applied to an international education/research nursing program. Appropriate measures for each were developed and ways to improve the program were…

  9. Treatment of hemicrania continua: case series and literature review.

    Science.gov (United States)

    Moura, Lídia Maria Veras Rocha de; Bezerra, José Marcelo Ferreira; Fleming, Norma Regina Pereira

    2012-01-01

    Hemicrania Continua (HC) is a primary, disabling headache characterized by a continuous unilateral pain and responsive to indomethacin. There are symptoms common to the trigeminal-autonomic cephalalgias and migraine that complicate the diagnosis. This review aims to describe HC in a case series and review the best available evidence on alternative therapies. A systematic review of medical records and diaries of pain of 1,600 patients treated between January 1992 and January 2011 in a headache outpatient clinic. Ten patients with a possible diagnosis of hemicrania continua were selected; seven were diagnosed with HC according to the II International Classification of Headache Disorders. None of the patients had received the correct diagnosis before being treated at the outpatient clinic and the average time for treatment was 12 years. Prophylactic treatment was effective in 66.6% of cases with amitriptyline, 20% with gabapentin and 10% with topiramate. HC should be considered among the diagnostic hypotheses of patients with continuous headache, with no change in neurological examination and additional tests, regardless the age of onset. The standard treatment with indomethacin (100-150mg.day(-1)) has significant risks associated with both short and long term use and may not be a good choice for continuous use. Recent studies point out possible alternatives: gabapentin, topiramate, cyclooxygenase-2 inhibitors, piroxicam, beta-cyclodextrin, amitriptyline, melatonin. Other drugs were described in different reports as efficient, but most of them were considered inefficient in other HC cases. Copyright © 2012 Elsevier Editora Ltda. All rights reserved.

  10. Longus colli tendinitis. A review of literature and case series

    Directory of Open Access Journals (Sweden)

    Shawky Ahmed

    2017-01-01

    Full Text Available Purpose: To increase the awareness of longus colli tendinitis (LCT among spine specialists and to present a practical overview of diagnostic and treatment options, so that unnecessary interventions are avoided. Five sample cases from a German spine center will also be presented. Methods: Literature review and case series. A PubMed search was performed in May 2015, and the articles found were reviewed for clinical presentation, investigations, and treatment. The frequency of publication of LCT cases and the specialty of journals were also noted. Recent cases treated in our institution were also reviewed. The clinical findings, investigations, and therapeutic interventions were summarized. Results: The PubMed search from May 2015 found 104 articles, published over 51 years, on the topic of LCT. Only four were published in spine journals. A review of this literature yielded a total of 242 cases. The classic clinical triad included neck pain, limitation of movements, and swallowing complaints. C-reactive Protein (CRP values were available in 21 cases (mean 23.66 mg/dL. A contrast-enhanced computed tomography (CT scan was the best diagnostic modality. LCT is usually a self-limiting condition, but non-steroidal anti-inflammatory drugs (NSAIDs may help alleviate discomfort. Five cases of LCT were diagnosed and treated in our center over the past three years. Conclusions: LCT, which is uncommon and has non-specific symptoms, is often referred to spine centers. Spine specialists should be aware of its clinical presentation and radiographic findings in order to avoid unnecessary interventions. The condition is self-limiting and can be treated conservatively.

  11. Arachnoiditis ossificans: clinical series and review of the literature.

    Science.gov (United States)

    Maulucci, Christopher M; Ghobrial, George M; Oppenlander, Mark E; Flanders, Adam E; Vaccaro, Alexander R; Harrop, James S

    2014-09-01

    Ossification of the leptomeninges, or arachnoiditis ossificans (AO) of the spine resulting in neurologic decline is a rarely reported disease. To date, there are 72 cases in the literature. The natural history of the disease and the best management strategy for patients with this condition is unknown. A series of five cases is presented adding to the relative paucity of knowledge of this potentially debilitating disease. A retrospective review of five cases of patients with arachnoiditis ossificans from 2009 to 2013 was conducted. All cases were obtained from a single institution. The diagnosis was based upon computed tomography (CT) and magnetic resonance imaging (MRI) studies. All five patients in the series were found have a history of prior spinal procedures. Three of the five patients had no history of intradural procedures or violation of the dura. Three of the patients underwent surgery to address neurologic deficits related to AO. Surgical intervention mainly consisted of decompression via laminectomy without resection of the intradural bony lesions. All patients improved neurologically postoperatively. Arachnoiditis ossificans is a rare disease typically affecting the thoracolumbar spine. It may result in devastating neurological deficits. There is no consensus as to the appropriate treatment strategy and the surgical procedures can be technically demanding due to the tight adherence of the abnormal bone to neural structures. For those patients who exhibit no symptoms referable to the AO, close observation may be performed. However, once progressive neurologic deficits occur due to AO, decompression via laminectomy can be a successful strategy. Copyright © 2014 Elsevier B.V. All rights reserved.

  12. Alkali-related ocular burns: a case series and review.

    Science.gov (United States)

    Bunker, Daniel J L; George, Robert J; Kleinschmidt, Andrew; Kumar, Rohit J; Maitz, Peter

    2014-01-01

    Alkali burns are known to possess high pathological potential because of their inherent ability to lyse cell membranes and penetrate intraocular structures with devastating results. The authors aimed to evaluate the most common cause of this presentation, the current treatment approaches to injury, and eventual outcome as related to severity. The authors performed a retrospective review of all patients who sustained chemical-related ocular injuries seen at the Concord Hospital Burns Unit, Australia between January 2005 and March 2012. Management was based on cooperation between ophthalmic staff and the burns unit, with emphasis on early aggressive intervention and rigorous follow-up. The records of 39 patients who presented with chemical-related injury were assessed, 12 of whom had confirmed alkali burns involving the cornea. The most commonly implicated agent was sodium hydroxide, usually in the context of otherwise trivial domestic accidents. Acute medical management included copious irrigation and the use of analgesics, cycloplegics, and topical antibiotics. In half the cases, steroid drops and oral vitamin C were also used. Ten of the 12 patients (83%) had return to premorbid visual acuity. Complications included cicatrical ectropion (n = 1), pseudoexfoliative syndrome (n = 1), and symblepharon (n = 1). Surgical correction was needed in the one patient with cicatrical ectropion. This case series shows that appropriate acute management minimizes the potentially devastating sequelae of ocular alkali burns. Emphasis should be placed on prevention of domestic and workplace injuries when using alkaline products.

  13. The jugular foramen schwannomas: review of the large surgical series.

    Science.gov (United States)

    Bakar, Bulent

    2008-11-01

    Jugular foramen schwannomas are uncommon pathological conditions. This article is constituted for screening these tumors in a wide perspective. One-hundred-and-ninty-nine patients published in 19 articles between 1984 to 2007 years was collected from Medline/Index Medicus. The series consist of 83 male and 98 female. The mean age of 199 operated patients was 40.4 years. The lesion located on the right side in 32 patients and on the left side in 60 patients. The most common presenting clinical symptoms were hearing loss, tinnitus, disphagia, ataxia, and hoarseness. Complete tumor removal was achieved in 159 patients. In fourteen patients tumor reappeared unexpectedly. The tumor was thought to originate from the glossopharyngeal nerve in forty seven cases; vagal nerve in twenty six cases; and cranial accessory nerve in eleven cases. The most common postoperative complications were lower cranial nerve palsy and facial nerve palsy. Cerebrospinal fluid leakage, meningitis, aspiration pneumonia and mastoiditis were seen as other complications. This review shows that jugular foramen schwannomas still have prominently high morbidity and those complications caused by postoperative lower cranial nerve injury are life threat.

  14. A meaningful MESS (Medical Education Scholarship Support

    Directory of Open Access Journals (Sweden)

    Shari A. Whicker

    2016-07-01

    Full Text Available Background: Graduate medical education faculty bear the responsibility of demonstrating active research and scholarship; however, faculty who choose education-focused careers may face unique obstacles related to the lack of promotion tracks, funding, career options, and research opportunities. Our objective was to address education research and scholarship barriers by providing a collaborative peer-mentoring environment and improve the production of research and scholarly outputs. Methods: We describe a Medical Education Scholarship Support (MESS group created in 2013. MESS is an interprofessional, multidisciplinary peer-mentoring education research community that now spans multiple institutions. This group meets monthly to address education research and scholarship challenges. Through this process, we develop new knowledge, research, and scholarly products, in addition to meaningful collaborations. Results: MESS originated with eight founding members, all of whom still actively participate. MESS has proven to be a sustainable unfunded local community of practice, encouraging faculty to pursue health professions education (HPE careers and fostering scholarship. We have met our original objectives that involved maintaining 100% participant retention; developing increased knowledge in at least seven content areas; and contributing to the development of 13 peer-reviewed publications, eight professional presentations, one Masters of Education project, and one educational curriculum. Discussion: The number of individuals engaged in HPE research continues to rise. The MESS model could be adapted for use at other institutions, thereby reducing barriers HPE researchers face, providing an effective framework for trainees interested in education-focused careers, and having a broader impact on the education research landscape.

  15. Bizarre Bequests and Strange Scholarships

    Science.gov (United States)

    Godfrey, Cullen M.

    2009-01-01

    There is a scholarship at the University of Texas at Austin endowed by friends of a faculty member whose cat died. The scholarship, which is named for the cat, benefits students in the liberal arts honors program who love cats and who also plan to major in English. People have always been generous to colleges and universities, but they have not…

  16. Scholarship can help ideas flourish.

    Science.gov (United States)

    Pearce, Lynne

    2016-03-09

    Scholarships from the Florence Nightingale Foundation are providing nurses with the financial means to put innovative ideas into practice. Nurses from all four countries of the UK can apply for leadership, travel and research scholarships to support their career development and help improve patient care.

  17. Three on a Match: Gary A. Olson on Rigor, Reliability, and Quality Control in Digital Scholarship

    Science.gov (United States)

    Jensen, Kyle

    2009-01-01

    This interview examines the relationship between digital scholarship and the politics of higher education. In doing so, it advances a series of recommendations that aim to help digital scholars and digital scholarship achieve an increased level of stature in the academic community.

  18. Developing a scholarship community.

    Science.gov (United States)

    Cumbie, Sharon; Weinert, Clarann; Luparell, Susan; Conley, Virginia; Smith, James

    2005-01-01

    To report the results of a multidisciplinary, interinstitutional writing support group established to facilitate faculty scholarly productivity. ORGANIZING CONCEPT: The road to scholarship can be filled with many obstacles, among them time constraints, teaching and meeting demands, student needs, office interruptions, and lack of colleagueship. The problems associated with lack of colleagueship, in particular, can be compounded for faculty who work in isolated contexts with few, if any, senior faculty to serve as mentors. METHODS OF DEVELOPMENT: The Western Writers Coercion Group evolved over a 2-year period from a small group of nursing faculty at a single institution to include, by its second year, 21 faculty from five western university campuses and three academic disciplines. The group met biweekly via teleconference with the objectives of defining and accomplishing realistic individual scholarship goals and providing a forum for the critical exchange of ideas. The ongoing support and mentoring of the group led to significant writing outcomes in the form of manuscripts submitted for publication, abstracts submitted for conference presentation, grant proposals developed, and collegial relationships formed. Although the benefits of group participation varied somewhat for faculty at different points in the career trajectory, they seemed to accrue at all levels of development. Group members underscored the many less quantifiable advantages of group participation: exposure to broader professional perspectives, the formation of key professional relationships, the enrichment of multidisciplinary input, and individualized assistance with time management, goal setting, and actual drafts. The structure and experience of this group, which continues to meet regularly, might be a model to guide other groups of scholars who face geographic isolation and who struggle with balancing time and work and finding motivation for the process of writing.

  19. Review article: Methodology for the 'rapid review' series on musculoskeletal injuries in the emergency department.

    Science.gov (United States)

    Strudwick, Kirsten; McPhee, Megan; Bell, Anthony; Martin-Khan, Melinda; Russell, Trevor

    2018-02-01

    Musculoskeletal injuries are a common presentation to the ED, with significant costs involved in the management of these injuries, variances in care within the ED and associated morbidity. A series of rapid review papers were completed to guide best practice for the assessment and management of common musculoskeletal injuries presenting to the ED. This paper presents the methodology used across the rapid reviews. PubMed, CINAHL, EMBASE, TRIP and the grey literature, including relevant organisational websites, were searched in 2015. The search was repeated consistently for each topic area (injuries of the foot and ankle, knee, hand and wrist, elbow, shoulder, lumbar spine and cervical spine). English-language primary studies, systematic reviews and guidelines that were published in the last 10 years and addressed acute musculoskeletal injury management were considered for inclusion. Data extraction of each included article was conducted, followed by a quality appraisal. The extracted data from each article was synthesised to group similar evidence together. For each rapid review, the evidence has been organised in a way that a clinician can direct their attention to a specific component of the clinical cycle of care in the ED, such as the assessment, diagnostic tests, management and follow-up considerations from ED. The series of rapid reviews are designed to foster evidence-based practice within the ED, targeting the injuries most commonly presenting. The reviews provide clinicians in EDs with rapid access to the best current evidence, which has been synthesised and organised to assist decision-making. © 2017 Australasian College for Emergency Medicine and Australasian Society for Emergency Medicine.

  20. Academic Primer Series: Key Papers About Peer Review.

    Science.gov (United States)

    Yarris, Lalena M; Gottlieb, Michael; Scott, Kevin; Sampson, Christopher; Rose, Emily; Chan, Teresa M; Ilgen, Jonathan

    2017-06-01

    Peer review, a cornerstone of academia, promotes rigor and relevance in scientific publishing. As educators are encouraged to adopt a more scholarly approach to medical education, peer review is becoming increasingly important. Junior educators both receive the reviews of their peers, and are also asked to participate as reviewers themselves. As such, it is imperative for junior clinician educators to be well-versed in the art of peer reviewing their colleagues' work. In this article, our goal was to identify and summarize key papers that may be helpful for faculty members interested in learning more about the peer-review process and how to improve their reviewing skills. The online discussions of the 2016-17 Academic Life in Emergency Medicine (ALiEM) Faculty Incubator program included a robust discussion about peer review, which highlighted a number of papers on that topic. We sought to augment this list with further suggestions by guest experts and by an open call on Twitter for other important papers. Via this process, we created a list of 24 total papers on the topic of peer review. After gathering these papers, our authorship group engaged in a consensus-building process incorporating Delphi methods to identify the papers that best described peer review, and also highlighted important tips for new reviewers. We found and reviewed 24 papers. In our results section, we present our authorship group's top five most highly rated papers on the topic of peer review. We also summarize these papers with respect to their relevance to junior faculty members and to faculty developers. We present five key papers on peer review that can be used for faculty development for novice writers and reviewers. These papers represent a mix of foundational and explanatory papers that may provide some basis from which junior faculty members might build upon as they both undergo the peer-review process and act as reviewers in turn.

  1. 45 CFR 1801.41 - Scholarship stipends.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Scholarship stipends. 1801.41 Section 1801.41 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Payments to Finalists and Scholars § 1801.41 Scholarship stipends...

  2. Review of Worcestershire On-line Fabric Type Series website

    Directory of Open Access Journals (Sweden)

    Beverley Nenk

    2003-06-01

    Full Text Available The study of archaeological ceramics is advanced through the creation and development of regional and national pottery type-series, which contain samples of each type of pottery identified from a particular area or region. Pottery researchers working in any period, from prehistoric to post-medieval, require access to such type-series, and to their associated data, in order to be able to advance the identification of all types of pottery, not only those types produced in the local area, but those produced in surrounding regions, as well as those imported from abroad. The publication of such type-series, as well as their accessibility to researchers, is essential if the information they contain is to be disseminated. The development of the Worcestershire On-Line Fabric Type Series is the first stage in a remarkable project designed to make the complete fabric and form type series for Worcestershire ceramics accessible on the internet. As part of the Historic Environment Record for Worcestershire, formerly the Sites and Monuments Record, it is designed to improve access to finds and environmental data, with the aim of encouraging and facilitating research. Funded by Worcestershire County Council as part of its commitment to e-government, it is being developed by Worcestershire County Council Archaeology Service with OxfordArchDigital. It is one of a proposed series of on-line specialist resources (to include, for example, clay pipes, environmental archaeology, flint tools, historic buildings, which are also designed to stand alone as research tools. The ceramics website is the first part of Pottery in Perspective, a web-based project to provide information on the pottery used and made in Worcestershire from prehistory to c. 1900AD.

  3. AHP 40: Review: TIBETAN FOLKTALES (WORLD FOLKLORE SERIES

    Directory of Open Access Journals (Sweden)

    Christine Murphy

    2016-02-01

    Full Text Available Tibetan Folktales brings a welcome addition to the well-respected World Folklore Series, published by Libraries Unlimited, an imprint of ABC-CLIO LLC. The primary author, Haiwang Yuan, Professor of Library Public Services at Western Kentucky University, has also written two other texts in the series, The Magic Lotus Lantern and Other Tales from the Han Chinese, and Princess Peacock: Tales from the Other Peoples of China, winner of the 2009 Aesop Accolade Award for the Children's Section of the American Folklore Society. ...

  4. Clinical review: Ectopic cervical thyroid carcinoma--review of the literature with illustrative case series.

    Science.gov (United States)

    Klubo-Gwiezdzinska, Joanna; Manes, R Peter; Chia, Stanley H; Burman, Kenneth D; Stathatos, Nikolaos A; Deeb, Ziad E; Wartofsky, Leonard

    2011-09-01

    More than 99% of thyroid cancers arise eutopically within the thyroid gland. The most frequent sites of ectopic thyroid tissue are lingual, sublingual, thyroglossal, laryngotracheal, and lateral cervical. Thyroid tissue can also be found in remote structures that were associated with the thyroid anlage during development, including the esophagus, mediastinum, heart, aorta, adrenal, pancreas, gallbladder, and skin. Ectopic thyroid tissue can be subject to the same pathological processes as normal eutopic thyroid tissue such as inflammation, hyperplasia, and tumorigenesis. The aim of this review is to describe aspects of thyroid cancer arising from the ectopic thyroid tissue in the neck in regard to epidemiology, diagnosis, and treatment and to present an illustrative series of cases of ectopic thyroid cancer. We have searched the PubMed database for articles including the keywords "ectopic thyroid cancer" published between January 1, 1960, and January 1, 2011. As references, we used clinical case series, case reports, review articles, and practical guidelines focused on ectopic thyroid cancer confined to the neck region. The possibility of an ectopic thyroid cancer should be considered in the differential diagnosis of a pathological mass in the neck. Treatment of ectopic cervical thyroid cancer is based predominantly on the surgical excision of the malignant lesion. Management strategies, including performance of total thyroidectomy, neck dissection, and treatment with radioiodine, should be based on individualized risk stratification.

  5. Emotional Intelligence Research within Human Resource Development Scholarship

    Science.gov (United States)

    Farnia, Forouzan; Nafukho, Fredrick Muyia

    2016-01-01

    Purpose: The purpose of this study is to review and synthesize pertinent emotional intelligence (EI) research within the human resource development (HRD) scholarship. Design/methodology/approach: An integrative review of literature was conducted and multiple electronic databases were searched to find the relevant resources. Using the content…

  6. A writer's guide to education scholarship: Qualitative education scholarship (part 2).

    Science.gov (United States)

    Chan, Teresa M; Ting, Daniel K; Hall, Andrew Koch; Murnaghan, Aleisha; Thoma, Brent; McEwen, Jill; Yarris, Lalena M

    2017-05-19

    Education scholarship can be conducted using a variety of methods, from quantitative experiments to qualitative studies. Qualitative methods are less commonly used in emergency medicine (EM) education research but are well-suited to explore complex educational problems and generate hypotheses. We aimed to review the literature to provide resources to guide educators who wish to conduct qualitative research in EM education. We conducted a scoping review to outline: 1) a list of journals that regularly publish qualitative educational papers; 2) an aggregate set of quality markers for qualitative educational research and scholarship; and 3) a list of quality checklists for qualitative educational research and scholarship. We found nine journals that have published more than one qualitative educational research paper in EM. From the literature, we identified 39 quality markers that were grouped into 10 themes: Initial Grounding Work (preparation, background); Goals, Problem Statement, or Question; Methods (general considerations); Sampling Techniques; Data Collection Techniques; Data Interpretation and Theory Generation; Measures to Optimize Rigour and Trustworthiness; Relevance to the Field; Evidence of Reflective Practice; Dissemination and Reporting. Lastly, five quality checklists were found for guiding educators in reporting their qualitative work. Many problems that EM educators face are well-suited to exploration using qualitative methods. The results of our scoping review provide publication venues, quality indicators, and checklists that may be useful to EM educators embarking on qualitative projects.

  7. Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series

    OpenAIRE

    Lei, Xiang; Chen, Jing; Ren, Jingtian; Li, Yan; Zhai, Jingbo; Mu, Wei; Zhang, Li; Zheng, Wenke; Tian, Guihua; Shang, Hongcai

    2015-01-01

    Objective. To summarize the characteristics and analysis of relevant factors and to give references for prevention and further study of liver damage associated with Polygonum multiflorum Thunb. (HSW), we provide a systematic review of case reports and case series about liver damage associated with HSW. Methods. An extensive search of 6 medical databases was performed up to June 2014. Case reports and case series involving liver damage associated with HSW were included. Results. This review co...

  8. Policies Shaping South African Scholarship: Production and Reproduction, or Diversity in the Pursuit of Knowledge?

    Science.gov (United States)

    Weber, Everard

    2011-01-01

    The article reviews the roles played by the Department of Education and the National Research Foundation in South Africa in defining the meaning of scholarship and in evaluating and funding it. The ideas that inform policy and practice include: the view that scholarship must serve the requirements of the national economy in becoming more globally…

  9. SLE and Tuberculosis: A Case Series and Review of Literature.

    Science.gov (United States)

    Bhattacharya, Prasanta Kumar; Jamil, Md; Roy, Aakash; Talukdar, Kishore Kumar

    2017-02-01

    Systemic Lupus Erythematosus (SLE) and Tuberculosis (TB) are intricately related with an increase in the risk of TB in SLE. Primary mechanisms pertaining to the increased susceptibility for TB are the inherent immunodeficient state of SLE and use of immunosuppressant agents in the treatment of SLE. We report a case series of five female patients of SLE with TB who presented between January 2015 and December 2015 in a tertiary care teaching hospital in North Eastern India. All the patients were young to middle aged females having SLE with or without lupus nephritis who were on immunosuppressive therapy with corticosteroids, mycophenolate mofetil or cyclophosphamide. Two of the cases had sputum positive pulmonary tuberculosis while rest had Extra-Pulmonary TB (EPTB). The response to anti-tubercular therapy led to clinical improvement in all the cases except one who had an adverse outcome. Our series further substantiates the increased risk of TB in SLE thus, prompting further research towards better management of these two disease entities in conjunction.

  10. Software Development Group. Software Review Center. Microcomputing Working Paper Series.

    Science.gov (United States)

    Perkey, Nadine; Smith, Shirley C.

    Two papers describe the roles of the Software Development Group (SDG) and the Software Review Center (SRC) at Drexel University. The first paper covers the primary role of the SDG, which is designed to assist Drexel faculty with the technical design and programming of courseware for the Apple Macintosh microcomputer; the relationship of the SDG…

  11. Takotsubo Cardiomyopathy: A Case Series and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Merchant, Emily E

    2008-05-01

    Full Text Available Takotsubo cardiomyopathy (TCM is an unusual form of acute cardiomyopathy showing left ventricular apical ballooning. It is often triggered by intense physical or emotional distress. We report here four cases of TCM and a review of the literature on the topic.

  12. Peripheral cemento-ossifying fibroma: case series literature review.

    Science.gov (United States)

    Verma, Esha; Chakki, Arunkumar Bhimashankar; Nagaral, Sharanbasappa Chandrashekar; Ganji, Kiran Kumar

    2013-01-01

    THE CONCEPT OF FIBROOSSEOUS LESIONS OF BONE HAS EVOLVED OVER THE LAST SEVERAL DECADES AND NOW INCLUDES TWO MAJOR ENTITIES: fibrous dysplasia and ossifying fibroma. Peripheral cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. It predominantly affects adolescents and young adults, with peak prevalence between 10 and 19 yrs. The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of confusion regarding terminology and the criteria for its diagnosis. The cemento-ossifying fibroma is odontogenic in origin, whereas ossifying fibroma is of bony origin. Lesions histologically similar to peripheral ossifying fibroma have been given various names in existing literature. Therefore, we present and discuss in this paper a series of cases of peripheral cemento-ossifying fibroma emphasizing the differential diagnosis.

  13. Glaucoma Surgery in Pregnancy: A Case Series and Literature Review

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Razeghinejad

    2016-09-01

    Full Text Available Glaucoma management in pregnant patients is a real challenge, especially when the glaucoma is not controlled with medications. We report the results of 6 incisional glaucoma surgeries for the management of medically uncontrolled glaucoma patients during pregnancy. This retrospective, case series was conducted on the 6 eyes of 3pregnant patients with uncontrolled glaucoma using maximum tolerable medications. Details of the glaucoma surgical management of these patients as well as their postoperative care and pregnancy and clinical outcomes on longitudinal follow-up are discussed. All 3 patients had juvenile open-angle glaucoma and were on various anti-glaucoma medications, including oral acetazolamide. The first case described underwent trabeculectomy without antimetabolites in both eyes because of uncontrolled intraocular pressure with topical medications. The surgery was done with topical lidocaine jelly and subconjunctival lidocaine during the second and third trimesters. The second patient had an Ahmed valve implantation in both eyes during the second and third trimesters because of uncontrolled IOP with topical medications and no response to selective laser trabeculoplasty. Surgery was done with topical tetracaine and subconjunctival and sub-Tenon’s lidocaine. The third case had a Baerveldt valve implantation under general anesthesia in the second trimester. In selected pregnant glaucoma patients with medically uncontrolled intraocular pressure threatening vision, incisional surgery may lead to good outcomes for the patient with no risk for the fetus.

  14. Partisan Scholarship in Technoscientific Controversies

    DEFF Research Database (Denmark)

    Galis, Vasilis; Hansson, Anders

    2012-01-01

    are characterised by differences in the motives underlying epistemological choices of research topic and method, personal commitments to the fields studied, use of research findings in controversies, and positioning of results in wider debates. Two examples help to illustrate partisan scholarship: first, a study......Several academic traditions have addressed epistemological objectivity and/or partisanship in the study of technoscientific controversies. On the one hand, positivist and relativist scholars agree that the political commitments of the social researcher should not impinge on scientific enquiry...... epistemological assumptions underpinning sociotechnical systems, especially when it comes to technoscientific controversies. Supporting STS partisan scholarship, therefore, enables greater social and democratic engagement with technoscientific development....

  15. RHUPUS Syndrome in Children: A Case Series and Literature Review

    Directory of Open Access Journals (Sweden)

    Vahid Ziaee

    2013-01-01

    Full Text Available Objective. Overlap of juvenile idiopathic arthritis (JIA and juvenile systemic lupus erythematosus (JSLE is a rare clinical condition in children. This condition has been described as RHUPUS syndrome. Prevalence of this syndrome and 3 cases are reported in this paper. Cases Presentation. During 10 years, 3 patients with SLE had chronic arthritis before or after diagnosis of SLE. Prevalence of this disorder in JSLE was 2.5%. Two patients were females and one of them was a male. According to our review, mean delay between chronic joint involvement and JSLE diagnosis was 50.1 months. In our case report, two females had joint erosion and one of them died due to heart failure, but in the literature review, just 45% cases had joint erosion and 70% cases were polyarticulare form. Conclusion. RHUPUS is unusual presentation of lupus in children. It seems that clinical feature and outcome of RHUPUS syndrome are different in children due to difference between RA and JIA. We suggest juvenile RHUPUS for overlap of JIA and JSLE.

  16. Frictional alopecia of the distal legs: case series and review.

    Science.gov (United States)

    Zhao, Johnny; Cohen, Philip R

    2016-08-15

    BackgroundAcquired alopecia of the lower legs may occur secondary to friction due to socks, footwear, or both on the lower extremities. There is scant literature that reports on this phenomenon.Methods and MaterialsWe describe 5 patients who presented with alopecia of their lower legs induced by socks, footwear, or both. We reviewed PubMed for the following terms: ankle alopecia, friction alopecia, frictional alopecia, lower extremity alopecia, non-scarring leg alopecia, and sock alopecia. We also reviewed papers containing these terms and their references.ResultsAcquired frictional alopecia of the lower extremities is often an asymptomatic condition found incidentally on physical examination. The condition can persist for many years despite removal of the source of friction.ConclusionThe incidence of acquired frictional alopecia of the lower extremities may be greater than reflected in previously published reports. It is a non-scarring subtype of alopecia that was noted as an incidental finding during the patient's dermatology appointment.

  17. The Scholarship of Practice in Applied Disciplines

    Science.gov (United States)

    Lyken-Segosebe, Dawn

    2017-01-01

    This chapter examines how the scholarship of practice is being used within applied disciplines and offers recommendations for colleges and universities regarding the implementation of the scholarship of practice for the discipline of higher education.

  18. Is Giving Scholarship Worth the Effort? Loyalty among Scholarship Recipients

    Science.gov (United States)

    Nurlida, Ismail

    2015-01-01

    To stay ahead of competition, a significant factor has now become of significance; student loyalty towards higher learning institutions. Hence, scholarship recipients have the expectation to demonstrate a certain degree of loyalty towards their education sponsor. In addition, they play an important role as opinion leaders and walking advertisement…

  19. Coccidioidomycosis in nonendemic area: case series and review of literature.

    Science.gov (United States)

    Desai, Neeraj R; McGoey, Robin; Troxclair, Dana; Simeone, Francesco; Palomino, Jaime

    2010-01-01

    Four cases of coccidioidomycosis, diagnosed in New Orleans, are described to illustrate the varied clinical presentation of this infection. The first is an immunocompromised elderly patient presenting with a cavitary lung lesion after travel to Utah. The second, a young immunocompetent patient presenting with acute respiratory distress syndrome after moving from Arizona. The third and fourth, young Hispanic immigrants with acquired immunodeficiency syndrome presenting with respiratory distress and sepsis. These are examples of different presentations, depending on immune competency, and illustrate the challenges in making this diagnosis in non-endemic areas. For two of the three patients who died an autopsy was obtained. We present the cases, show radiographic and pathological findings, and review the current literature on coccidioidomyocosis.

  20. Errors of Logic and Scholarship Concerning Dissociative Identity Disorder

    Science.gov (United States)

    Ross, Colin A.

    2009-01-01

    The author reviewed a two-part critique of dissociative identity disorder published in the "Canadian Journal of Psychiatry". The two papers contain errors of logic and scholarship. Contrary to the conclusions in the critique, dissociative identity disorder has established diagnostic reliability and concurrent validity, the trauma histories of…

  1. Articulating Performance Expectations for Scholarship at an Australian Regional University

    Science.gov (United States)

    Crookes, Patrick A.; Smith, Kylie M.; Else, Fabienne C.; Crookes, Ellie

    2016-01-01

    With an academic workforce undergoing transformation, it is vital that universities rethink how they define and value scholarship through their processes for academic promotion. A key part of this rethink is to review and refine existing documentation about promotion to reflect changing conceptions of scholarly work, in a way that enables scholars…

  2. 25 CFR 40.2 - Working scholarships.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Working scholarships. 40.2 Section 40.2 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION ADMINISTRATION OF EDUCATIONAL LOANS, GRANTS AND OTHER ASSISTANCE FOR HIGHER EDUCATION § 40.2 Working scholarships. Working scholarships may be granted...

  3. Imported brucellosis: A case series and literature review.

    Science.gov (United States)

    Norman, Francesca F; Monge-Maillo, Begoña; Chamorro-Tojeiro, Sandra; Pérez-Molina, Jose-Antonio; López-Vélez, Rogelio

    2016-01-01

    Brucellosis is one of the main neglected zoonotic diseases. Several factors may contribute to the epidemiology of brucellosis. Imported cases, mainly in travellers but also in recently arrived immigrants, and cases associated with imported products, appear to be infrequently reported. Cases of brucellosis diagnosed at a referral unit for imported diseases in Europe were described and a review of the literature on imported cases and cases associated with contaminated imported products was performed. Most imported cases were associated with traditional risk factors such as travel/consumption of unpasteurized dairy products in endemic countries. Cases associated with importation of food products or infected animals also occurred. Although a lower disease incidence of brucellosis has been reported in developed countries, a higher incidence may still occur in specific populations, as illustrated by cases in Hispanic patients in the USA and in Turkish immigrants in Germany. Imported brucellosis appears to present with similar protean manifestations and both classical and infrequent modes of acquisition are described, leading on occasions to mis-diagnoses and diagnostic delays. Importation of Brucella spp. especially into non-endemic areas, or areas which have achieved recent control of both animal and human brucellosis, may have public health repercussions and timely recognition is essential. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Scholarships for European vet students.

    Science.gov (United States)

    Egan, Jordon; Takacs, Daniella

    2017-02-25

    Every year, students from European vet schools can apply for $5000 scholarships, which aim to 'enhance the academic experience of students'. Among last year's recipients were Jordon Egan, from the Royal Veterinary College, and Daniella Takács, from the University of Veterinary Medicine in Budapest. British Veterinary Association.

  5. Rewarding Community-Engaged Scholarship

    Science.gov (United States)

    Saltmarsh, John; Giles, Dwight E., Jr.; Ward, Elaine; Buglione, Suzanne M.

    2009-01-01

    Higher education leaders seeking to reshape institutional identity and establish community engagement as a core institutional value ultimately have to address how to embed the values of community engagement in the institutional reward policies that define the faculty roles of teaching, scholarship, and service. Furthermore, since the research…

  6. Public Scholarship as a Vocation

    Science.gov (United States)

    Karp, Ivan

    2012-01-01

    The calling of public scholarship is inherently multifaceted, and often inherently controversial; public scholars have to accommodate different spheres of society, different cultural values and goods, and even different political agendas in their work. Unlike academic workers, public scholars rarely have the opportunity to do work that is driven…

  7. Adverse Events Associated with Yoga: A Systematic Review of Published Case Reports and Case Series

    OpenAIRE

    Holger Cramer; Carol Krucoff; Gustav Dobos

    2013-01-01

    While yoga is gaining increased popularity in North America and Europe, its safety has been questioned in the lay press. The aim of this systematic review was to assess published case reports and case series on adverse events associated with yoga. Medline/Pubmed, Scopus, CAMBase, IndMed and the Cases Database were screened through February 2013; and 35 case reports and 2 case series reporting a total of 76 cases were included. Ten cases had medical preconditions, mainly glaucoma and osteopeni...

  8. From Polarity to Plurality in Translation Scholarship

    Directory of Open Access Journals (Sweden)

    Abdolla Karimzadeh

    2012-09-01

    Full Text Available Review of the literature in translation studies shows that translation scholarship can be discussed in 3 Macro-levels including 1 Corpus-based studies, 2 Protocol-based studies, and 3 Systems- based studies. Researchers in the corpus-based studies test the hypothesis about the universals of translation. They also try to identify translation norms and regular linguistic patterns. This scholarship aims at showing that the language of translation is different from that of non-translation. The other purpose is to identify the techniques and strategies adopted by the translators. In protocol –based studies, the researchers study the mental activities and the individual behaviors of the translators while translating. They aim to describe the behavior of professional translators (versus translator trainees during the process of translation in a bid to identify how they chunk the source text (unit of translation and to describe how the translation trainees develop their translation competence. These studies are longitudinal for the reason that they aim to investigate the change of intended behaviors in the subjects of the study. Like corpus-based studies, they are experimental and data for analysis are collected by various methods including the translators’ verbal report, keystroke logging, eye tracking, and so on. Recently, in a method called “triangulation”, they combine the above-mentioned methods of data collection to test their hypotheses on a stronger experimental basis. To collect the data, they also employ the methods used in neurology (for example the technology of Electroencephalogram in order to obtain information on the physiological processes in the brains of the translators while translating. And finally in the systems-based studies, the researchers analyze more extended systems of production, distribution, and consumption of translations and their impacts on the target culture in a specific socio-cultural context. Differentiating

  9. Publishing Venues for Education Scholarship: A Needs Assessment.

    Science.gov (United States)

    Jordan, Jaime; Jones, David; Williams, Dustin; Druck, Jeffrey

    2016-06-01

    Education research is a developing field. It is unknown if there are adequate venues for scholarship distribution. The objectives of this study were to identify types of education scholarship produced, where this type of scholarship is published, barriers to achieving publication for education scholarship, and perceptions of adequacy of publication venues. Study participants were emergency medicine (EM) education and academic leaders who completed an online survey consisting of multiple-choice, completion, and 10-point Likert scale items. A total of 45 of 59 (76.3%) subjects completed the survey. A total of 33 of 45 (73.3%) respondents had published education scholarship. Most (29/44, 65.9%) felt that there were inadequate venues for publishing education scholarship. Of those who publish education scholarship, most (30/33; 90.9%) publish either less than one or one to two peer-reviewed products per year, but collaborate with others more frequently (less than one per year, 7/33, 21.2%; one or two per year, 17/33, 51.5%; three or four per year, 7/33, 21.2%; five or more per year, 2/33, 6.1%). The most frequently published scholarship were curricular innovations and original research, with mean ratings of 5.61 and 5.21, respectively, on a 10-point Likert scale. Peer-reviewed print journal was the most frequently utilized venue, with a mean rating of 6.21. Other venues (mean rating) include peer-reviewed online journal (4.0), MedEd Portal (3.58), free open-access education (3.47), newsletter (3.0), and curricular toolbox (2.55). The most common rejection reason was "not suitable for this journal/venue," with a mean rating of 5.33. Other reasons include research methodology (4.07), small sample size (4.17), single-site study (4.28), and misunderstanding of project purpose (4.10). Respondents believed that additional education supplements in journals would be most helpful in increasing successful publication, with a mean rating of 8.31. Other helpful items included a

  10. Science and Russian Orthodox Scholarship.

    Science.gov (United States)

    Hall, Karl; Bayuk, Dimitri

    2016-09-01

    In Russia the theme of science and religion found its strongest resonance at the levels of humanistic scholarship and Christianity in general, where visions of harmony dominated and doctrinal and confessional particularity was largely absent. The fraught relations of both the Holy Synod and the Imperial Academy of Sciences with the Russian state since the early eighteenth century had the collateral consequence of minimal institutional contacts between theology and natural philosophy. Though “scientific apologetics” eventually found a place in the seminaries, scientists did not contribute to this scholarship in the nineteenth century. The rare prominent scientist who entertained religious beliefs posited either harmony or conflict in public writings even more rarely, and it is the varieties of religious indifference—not solely Soviet in origin—that invite historical inquiry.

  11. Piriformis syndrome: a case series of 31 Bangladeshi people with literature review

    NARCIS (Netherlands)

    Siddiq, Abu Bakar; Hossain, Shawkat; Uddin, Mohammad Moin; Jahan, Israt; Khasru, Moshiur Rahman; Haider, Neaz Mahmud; Rasker, Johannes J.

    Aims To describe a series of piriformis syndrome patient among Bangladesh people with literature review. Methods Consecutive 31 piriformis syndrome patients were enrolled. Besides history and clinical examination, piriformis muscle thickness was also measured with diagnostic ultrasound (3.5 MHZ).

  12. The prevalence of child maltreatment across the globe: Review of a series of meta-analyses.

    NARCIS (Netherlands)

    Stoltenborgh, M.; Bakermans-Kranenburg, M.J.; Alink, L.R.A.; van IJzendoorn, M.H.

    2015-01-01

    In this review, we combine and compare the results of a series of meta-analyses on the prevalence of child sexual, physical and emotional abuse and physical and emotional neglect, including 244 publications and 551 prevalence rates for the various types of maltreatment. Child maltreatment research

  13. Furthering the understanding of parent-child relationships: a nursing scholarship review series. Part 5: parent-adolescent and teen parent-child relationships.

    Science.gov (United States)

    Riesch, Susan K; Anderson, Lori S; Pridham, Karen A; Lutz, Kristin F; Becker, Patricia T

    2010-07-01

    The purpose of this paper is to examine nursing's contribution to understanding the parent-adolescent and the teen parent-child relationships. Relationships between parents and adolescents may reflect turmoil and affect adolescents' health and development. The social and developmental contexts for teen parenting are powerful and may need strengthening. Several interventions to help teen mothers interact sensitively with their infants have been developed and tested. Nurse researchers have begun to provide evidence for practitioners to use in caring for families of adolescents and teen parents to acquire interaction skills that, in turn, may promote optimal health and development of the child.

  14. Education Scholarship and its Impact on Emergency Medicine Education.

    Science.gov (United States)

    Sherbino, Jonathan

    2015-11-01

    Emergency medicine (EM) education is becoming increasingly challenging as a result of changes to North American medical education and the growing complexity of EM practice. Education scholarship (ES) provides a process to develop solutions to these challenges. ES includes both research and innovation. ES is informed by theory, principles and best practices, is peer reviewed, and is disseminated and archived for others to use. Digital technologies have improved the discovery of work that informs ES, broadened the scope and timing of peer review, and provided new platforms for the dissemination and archiving of innovations. This editorial reviews key steps in raising an education innovation to the level of scholarship. It also discusses important areas for EM education scholars to address, which include the following: the delivery of competency-based medical education programs, the impact of social media on learning, and the redesign of continuing professional development.

  15. Change detection using landsat time series: A review of frequencies, preprocessing, algorithms, and applications

    Science.gov (United States)

    Zhu, Zhe

    2017-08-01

    The free and open access to all archived Landsat images in 2008 has completely changed the way of using Landsat data. Many novel change detection algorithms based on Landsat time series have been developed We present a comprehensive review of four important aspects of change detection studies based on Landsat time series, including frequencies, preprocessing, algorithms, and applications. We observed the trend that the more recent the study, the higher the frequency of Landsat time series used. We reviewed a series of image preprocessing steps, including atmospheric correction, cloud and cloud shadow detection, and composite/fusion/metrics techniques. We divided all change detection algorithms into six categories, including thresholding, differencing, segmentation, trajectory classification, statistical boundary, and regression. Within each category, six major characteristics of different algorithms, such as frequency, change index, univariate/multivariate, online/offline, abrupt/gradual change, and sub-pixel/pixel/spatial were analyzed. Moreover, some of the widely-used change detection algorithms were also discussed. Finally, we reviewed different change detection applications by dividing these applications into two categories, change target and change agent detection.

  16. 45 CFR 1801.62 - Recovery of scholarship funds.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Recovery of scholarship funds. 1801.62 Section 1801.62 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Duration of Scholarship § 1801.62 Recovery of scholarship...

  17. 42 CFR 57.2209 - Conditions of scholarship grant.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Conditions of scholarship grant. 57.2209 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2209 Conditions of scholarship grant. (a) Any scholarship grant made...

  18. 45 CFR 1801.61 - Termination of scholarship.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Termination of scholarship. 1801.61 Section 1801.61 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Duration of Scholarship § 1801.61 Termination of scholarship...

  19. 45 CFR 1801.1 - Annual Truman Scholarship competition.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Annual Truman Scholarship competition. 1801.1... SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM General § 1801.1 Annual Truman Scholarship competition. Each year, the Harry S. Truman Scholarship Foundation carries out a nationwide competition to...

  20. 42 CFR 57.2207 - Amount of scholarship grant.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Amount of scholarship grant. 57.2207 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2207 Amount of scholarship grant. (a) The amount of the scholarship...

  1. 45 CFR 1801.60 - Renewal of scholarship.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Renewal of scholarship. 1801.60 Section 1801.60 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Duration of Scholarship § 1801.60 Renewal of scholarship. It is the...

  2. 42 CFR 57.2208 - Payment of scholarship grant.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Payment of scholarship grant. 57.2208 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2208 Payment of scholarship grant. The portion of a scholarship grant...

  3. Traditional Chinese Medicine in Cancer Care: A Review of Case Series Published in the Chinese Literature

    Directory of Open Access Journals (Sweden)

    Guoyan Yang

    2012-01-01

    Full Text Available Traditional Chinese medicine (TCM has been widely used in cancer in China. Case series report a series of cases exposed to a certain intervention. To understand the current situation of case series of TCM for cancer, we performed this review. We included case series of cancer patients treated with TCM therapy. Electronic searches were conducted in four main Chinese databases until February 2011. A total of 1,217 reports of case series (92,945 patients were included. The top five types of cancer were lung cancer, liver cancer, stomach cancer, leukemia, and esophageal cancer. Leukopenia and hiccup treated by TCM were the most common adverse reactions after surgery or induced by chemo/radiotherapy. More than half of the patients were treated with TCM therapies alone. The application of herbal medicines especially formula based on syndrome differentiation was highly prevalent, and the typical administration route was oral usage. 1,182 reports were published in a structured format. The quantity of TCM case series for cancer treatment is substantial. Further studies should focus on the most common types of cancer and the most frequently applied TCM therapies. We presented a recommendation from the methodological point of view for the format of reporting.

  4. Student Affairs and the Scholarship of Practice

    Science.gov (United States)

    Hirschy, Amy S.; Wilson, Maureen E.

    2017-01-01

    Through professional associations and graduate preparation programs, members of the student affairs profession identify, communicate, and reinforce professional standards to promote the scholarship of practice.

  5. Designing Scholarships to Improve College Success: Final Report on the Performance-Based Scholarship Demonstration

    Science.gov (United States)

    Mayer, Alexander K.; Patel, Reshma; Rudd, Timothy; Ratledge, Alyssa

    2015-01-01

    Performance-based scholarships have two main goals: (1) to give students more money for college; and (2) to provide incentives for academic progress. MDRC launched the Performance-Based Scholarship (PBS) Demonstration in 2008 to evaluate the effectiveness of these scholarships in a diverse set of states, institutions, and low-income student…

  6. Breast phyllodes tumor: a review of literature and a single center retrospective series analysis.

    Science.gov (United States)

    Spitaleri, Gianluca; Toesca, Antonio; Botteri, Edoardo; Bottiglieri, Luca; Rotmensz, Nicole; Boselli, Sabrina; Sangalli, Claudia; Catania, Chiara; Toffalorio, Francesca; Noberasco, Cristina; Delmonte, Angelo; Luini, Alberto; Veronesi, Paolo; Colleoni, Marco; Viale, Giuseppe; Zurrida, Stefano; Goldhirsch, Aron; Veronesi, Umberto; De Pas, Tommaso

    2013-11-01

    Complete surgical resection is the standard treatment for localized breast phyllodes tumors. Post-surgical treatments are still a matter of debate. We carried out an overview of the literature to investigate the clinical outcome of patients with phyllodes tumor. A retrospective analysis of mono-institutional series has been included as well. We reviewed all the retrospective series reported from 1951 until April 2012. We analyzed cases treated at our institution from 1999 to 2010. Eighty-three articles (5530 patients; 1956 malignant tumors) were reviewed. Local recurrences were independent of histology. Distant recurrences were more frequent in the malignant tumors (22%). A total of 172 phyllodes tumors were included in the retrospective analysis. Prognosis of phyllodes tumors is excellent. There are no convincing data to recommend any adjuvant treatment after surgery. Molecular characterization may well provide new clues to permit identification of active treatments for the rare poor prognosis cases. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  7. Application of the Allan Variance to Time Series Analysis in Astrometry and Geodesy: A Review.

    Science.gov (United States)

    Malkin, Zinovy

    2016-04-01

    The Allan variance (AVAR) was introduced 50 years ago as a statistical tool for assessing the frequency standards deviations. For the past decades, AVAR has increasingly been used in geodesy and astrometry to assess the noise characteristics in geodetic and astrometric time series. A specific feature of astrometric and geodetic measurements, as compared with clock measurements, is that they are generally associated with uncertainties; thus, an appropriate weighting should be applied during data analysis. In addition, some physically connected scalar time series naturally form series of multidimensional vectors. For example, three station coordinates time series X, Y, and Z can be combined to analyze 3-D station position variations. The classical AVAR is not intended for processing unevenly weighted and/or multidimensional data. Therefore, AVAR modifications, namely weighted AVAR (WAVAR), multidimensional AVAR (MAVAR), and weighted multidimensional AVAR (WMAVAR), were introduced to overcome these deficiencies. In this paper, a brief review is given of the experience of using AVAR and its modifications in processing astrogeodetic time series.

  8. Sending Scholarship Students Abroad in Ottoman Empire

    Science.gov (United States)

    Kulaç, Onur; Özgür, Hüseyin

    2017-01-01

    The implementation of sending scholarship students abroad that started in the 19th century by Sultan Selim III in Ottoman Empire continued during the period of other Sultans became a significant reference point for the abroad scholarship policy of Turkey. The students that were firstly sent abroad especially for military training, were sent to…

  9. Legal Doctrinal Scholarship and Interdisciplinary Engagement

    NARCIS (Netherlands)

    M. Bodig (Matyas)

    2015-01-01

    textabstractThe paper offers a legal theoretical analysis of the disciplinary character of the contemporary practice of legal scholarship. It is assumed that the challenges of interdisciplinary engagement are particularly revealing about the nature of legal scholarship. The paper argues for an

  10. Renal transplant lithiasis: analysis of our series and review of the literature.

    Science.gov (United States)

    Stravodimos, Konstantinos G; Adamis, Stefanos; Tyritzis, Stavros; Georgios, Zavos; Constantinides, Constantinos A

    2012-01-01

    Renal transplant lithiasis represents a rather uncommon complication. Even rare, it can result in significant morbidity and a devastating loss of renal function if obstruction occurs. We present our experience with graft lithiasis in our series of renal transplantations and review the literature regarding the epidemiology, pathophysiology, and current therapeutic strategies in the management of renal transplant lithiasis. In a retrospective analysis of a consecutive series of 1525 renal transplantations that were performed between January 1983 and March 2007, 7 patients were found to have allograft lithiasis. In five cases, the calculi were localized in the renal unit, and in two cases, in the ureter. A review in the English language was also performed of the Medline and PubMed databases using the keywords renal transplant lithiasis, donor-gifted lithiasis, and urological complications after kidney transplantation. Several retrospective studies regarding the incidence, etiology, as well as predisposing factors for graft lithiasis were reviewed. Data regarding the current therapeutic strategies for graft lithiasis were also evaluated, and outcomes were compared with the results of our series. Most studies report a renal transplant lithiasis incidence of 0.4% to 1%. In our series, incidence of graft lithiasis was 0.46% (n=7). Of the seven patients, three were treated via percutaneous nephrolithotripsy (PCNL); in three patients, shockwave lithotripsy (SWL) was performed; and in a single case, spontaneous passage of a urinary calculus was observed. All patients are currently stone free but still remain under close urologic surveillance. Renal transplant lithiasis requires vigilance, a high index of suspicion, prompt recognition, and management. Treatment protocols should mimic those for solitary kidneys. Minimally invasive techniques are available to remove graft calculi. Long-term follow-up is essential to determine the outcome, as well as to prevent recurrence.

  11. Grading and staging mucinous neoplasms of the appendix: a case series and review of the literature.

    Science.gov (United States)

    Umetsu, Sarah E; Shafizadeh, Nafis; Kakar, Sanjay

    2017-11-01

    The grading and staging of appendiceal mucinous neoplasms is challenging and fraught with terminology problems, but has critical prognostic and therapeutic implications. We utilized a small case series to examine the grading and staging systems of appendiceal mucinous neoplasms and outline the evidence for the new systems proposed in the upcoming 8th edition of the American Joint Committee on Cancer (AJCC) Staging Manual. We reviewed 33 cases of appendiceal mucinous neoplasms with available clinical follow-up data, 6 of which were widely disseminated in the peritoneum. An additional 4 cases with disseminated peritoneal involvement were also reviewed. A detailed review of the literature was performed with an emphasis on features associated with disease recurrence and correlation of grade with outcome. Recurrence was not seen in 64 low-grade appendiceal mucinous neoplasms (LAMNs) confined to the muscularis propria in our series (n=21) or in the literature (n=43). Of cases of LAMN with neoplastic epithelium present beyond the muscularis propria, 64% (57/89) had peritoneal disease at the time of diagnosis or follow-up. A majority of studies of disseminated appendiceal mucinous neoplasms showed significant five-year survival differences using a three-tier grading scheme. Thus, LAMNs confined to the muscularis propria are best considered as in situ tumors, as these are cured with complete excision. A three-tier system has prognostic significance and should be used for grading of disseminated appendiceal mucinous neoplasms. The conclusions of this case series and literature review provide evidence to support the changes proposed in the 8th edition of the AJCC Staging Manual. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Patch testing with rubber series in Europe: a critical review and recommendation.

    Science.gov (United States)

    Warburton, Katharine L; Uter, Wolfgang; Geier, Johannes; Spiewak, Radoslaw; Mahler, Vera; Crépy, Marie-Noëlle; Schuttelaar, Marie Louise; Bauer, Andrea; Wilkinson, Mark

    2017-04-01

    Rubber additives constitute an important group of contact allergens, particularly in certain occupations. To collect information regarding the current practice of using a 'rubber series' in Europe, and discuss this against the background of evidence concerning the prevalence of allergy in order to derive a recommendation for a 'European rubber series'. The following were performed: (i) a survey targeting all members of the COST action 'StanDerm' consortium, (ii) analysis of rubber contact allergy data in the database of the European Surveillance System on Contact Allergies, and (iii) a literature review. Information from 13 countries was available, from one or several departments of dermatology, and occasionally occupational health. Apart from some substances tested only in single departments, a broad overlap regarding important allergens was evident, but considerable variation existed between departments. An up-to-date 'European rubber series' is recommended, with the exclusion of substances only of historical concern. A 'supplementary rubber series' containing allergens of less proven importance, requiring further analysis, is recommended for departments specializing in occupational contact allergy. These should be continually updated as new evidence emerges. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  13. 15 years of protest and media technologies scholarship: A sociotechnical timeline

    DEFF Research Database (Denmark)

    Neumayer, Christina; Rossi, Luca

    2016-01-01

    and techniques, and the social phenomena under investigation. The article concludes by identifying major trends in protest and media technologies scholarship over the past 15 years. The sociotechnical timeline enhances our understanding of academic discourse at the intersection of protest and media technologies......This article investigates the relationship between the invention of new media technologies and scholarship concerning protest and political engagement. Building on an innovative approach that moves beyond a systematic literature review, this article contributes to our understanding of scholarship...... concerning digital communication technologies and how they may have been adopted and shaped protest movements and political engagement. Based on visualisations, we draw a sociotechnical timeline of protest and media technology scholarship within three dimensions: Technological development, methods...

  14. 15 years of protest and media technologies scholarship: A sociotechnical timeline

    DEFF Research Database (Denmark)

    Neumayer, Christina; Rossi, Luca

    2016-01-01

    This article investigates the relationship between the invention of new media technologies and scholarship concerning protest and political engagement. Building on an innovative approach that moves beyond a systematic literature review, this article contributes to our understanding of scholarship...... and techniques, and the social phenomena under investigation. The article concludes by identifying major trends in protest and media technologies scholarship over the past 15 years. The sociotechnical timeline enhances our understanding of academic discourse at the intersection of protest and media technologies...... concerning digital communication technologies and how they may have been adopted and shaped protest movements and political engagement. Based on visualisations, we draw a sociotechnical timeline of protest and media technology scholarship within three dimensions: Technological development, methods...

  15. Review of current GPS methodologies for producing accurate time series and their error sources

    Science.gov (United States)

    He, Xiaoxing; Montillet, Jean-Philippe; Fernandes, Rui; Bos, Machiel; Yu, Kegen; Hua, Xianghong; Jiang, Weiping

    2017-05-01

    The Global Positioning System (GPS) is an important tool to observe and model geodynamic processes such as plate tectonics and post-glacial rebound. In the last three decades, GPS has seen tremendous advances in the precision of the measurements, which allow researchers to study geophysical signals through a careful analysis of daily time series of GPS receiver coordinates. However, the GPS observations contain errors and the time series can be described as the sum of a real signal and noise. The signal itself can again be divided into station displacements due to geophysical causes and to disturbing factors. Examples of the latter are errors in the realization and stability of the reference frame and corrections due to ionospheric and tropospheric delays and GPS satellite orbit errors. There is an increasing demand on detecting millimeter to sub-millimeter level ground displacement signals in order to further understand regional scale geodetic phenomena hence requiring further improvements in the sensitivity of the GPS solutions. This paper provides a review spanning over 25 years of advances in processing strategies, error mitigation methods and noise modeling for the processing and analysis of GPS daily position time series. The processing of the observations is described step-by-step and mainly with three different strategies in order to explain the weaknesses and strengths of the existing methodologies. In particular, we focus on the choice of the stochastic model in the GPS time series, which directly affects the estimation of the functional model including, for example, tectonic rates, seasonal signals and co-seismic offsets. Moreover, the geodetic community continues to develop computational methods to fully automatize all phases from analysis of GPS time series. This idea is greatly motivated by the large number of GPS receivers installed around the world for diverse applications ranging from surveying small deformations of civil engineering structures (e

  16. Genetic basis of familial isolated hyperparathyroidism: a case series and a narrative review of the literature.

    Science.gov (United States)

    Pontikides, Nikolaos; Karras, Spyridon; Kaprara, Athina; Anagnostis, Panagiotis; Mintziori, Gesthimani; Goulis, Dimitrios G; Memi, Eleni; Krassas, Gerasimos

    2014-07-01

    Primary hyperparathyroidism is a heterogeneous clinical entity. In the clinical setting, the diagnosis and management of familial isolated hyperparathyroidism (FIHP) and other familial hyperparathyroidism (FHPT) forms continue to rely on clinical, laboratory, and histological findings, with careful examination of the family. In this article, we report a case series of FIHP in a four-generation Greek family, with no identifiable gene mutations. Clinical approach and long-term follow-up are discussed and a narrative review of the genetic basis of this entity has been performed.

  17. Mucormycosis in Patients with Inflammatory Bowel Disease: Case Series and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Maheen Z. Abidi

    2014-01-01

    Full Text Available Mucormycosis is a rare and often fatal invasive fungal infection mostly seen in immune-compromised individuals. A high index of clinical suspicion is necessary, so that effective preemptive therapy can be started, as timely intervention is crucial. In this series we present three cases of invasive mucormycosis in patients with underlying inflammatory bowel disease that had received therapy with immunomodulators prior to the infection. All three had varied clinical manifestations. We also review the literature of invasive mucormycosis in patients with inflammatory bowel disease.

  18. Infrequent Reservoir‐Related Complications of Urologic Prosthetics: A Case Series and Literature Review

    Directory of Open Access Journals (Sweden)

    Tao Cui, MD

    2015-12-01

    Conclusion: Complications involving urologic prosthesis reservoirs, although rare, can have serious implications for patients. A high index of suspicion and familiarity with treatment options is required in order to allow timely diagnosis and appropriate treatment. Patients with prior major abdominal surgeries seem to be more prone to intestinal complications of reservoirs and warrant special concern. Cui T, Terlecki R, and Mirzazadeh M. Infrequent reservoir‐related complications of urologic prosthetics: A case series and literature review. Sex Med 2015;3:334–338.

  19. Sternoclavicular septic arthritis: a series of 5 cases and review of the literature.

    Science.gov (United States)

    Guillén Astete, Carlos; Aranda García, Yolanda; de la Casa Resino, Cristina; Carpena Zafrilla, María; Braña Cardeñosa, Adela; Roldan Moll, Fernando; Carballo, César; Zea Mendoza, Antonio

    2015-01-01

    Infectious arthritis is a medical emergency whose prognosis, in terms of general morbidity and the final functionality of the joint, depends on rapid diagnosis and treatment. The sternoclavicular joint is an area of low prevalence of this type of arthritis, although its frequency is often concentrated in immunosuppressed patients, users of parenteral drugs or after traumatic events. We present a series of 5 microbiologically documented cases of sternoclavicular septic arthritis, 3 of which occurred in immunocompetent patients, and a short review of this pathology. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  20. 42 CFR 136.323 - Scholarship and tuition.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Scholarship and tuition. 136.323 Section 136.323... J-3-Health Professions Preparatory Scholarship Program for Indians § 136.323 Scholarship and tuition. (a) Scholarship grant awards under this subdivision shall consist of: (1) A stipend of $400 per month...

  1. 38 CFR 17.604 - Application for the scholarship program.

    Science.gov (United States)

    2010-07-01

    ... scholarship program. 17.604 Section 17.604 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Va Health Professional Scholarship Program § 17.604 Application for the scholarship program. Each individual desiring a scholarship under this program must submit an accurate and complete...

  2. 42 CFR 136.370 - Pregraduate scholarship grants.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Pregraduate scholarship grants. 136.370 Section 136... J-8-Health Professions Pregraduate Scholarship Program for Indians § 136.370 Pregraduate scholarship grants. (a) Pregraduate scholarship grants may be awarded under this subdivision and section 103 of the...

  3. 42 CFR 136.330 - Indian health scholarships.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Indian health scholarships. 136.330 Section 136.330... J-4-Indian Health Scholarship Program § 136.330 Indian health scholarships. Indian Health Scholarships will be awarded by the Secretary pursuant to 338A through 339G of the Public Health Service Act...

  4. 42 CFR 136.373 - Scholarship and tuition.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Scholarship and tuition. 136.373 Section 136.373... J-8-Health Professions Pregraduate Scholarship Program for Indians § 136.373 Scholarship and tuition. (a) Scholarship grant awards under this subdivision shall consist of: (1) A stipend of $400 per month...

  5. 42 CFR 136.320 - Preparatory scholarship grants.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Preparatory scholarship grants. 136.320 Section 136... J-3-Health Professions Preparatory Scholarship Program for Indians § 136.320 Preparatory scholarship grants. Scholarship grants may be awarded under this subdivision and section 103 of the act for the...

  6. 28 CFR 345.84 - The FPI scholarship fund.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false The FPI scholarship fund. 345.84 Section... INDUSTRIES (FPI) INMATE WORK PROGRAMS FPI Inmate Training and Scholarship Programs § 345.84 The FPI scholarship fund. FPI shall award post-secondary school scholarships to selected, qualified inmate workers...

  7. Ophthalmic Timolol Hallucinations: A Case Series and Review of the Literature.

    Science.gov (United States)

    Nanda, Tavish; Rasool, Nailyn; Callahan, Alison B; Stamper, Robert L; Odel, Jeffrey G

    2017-09-01

    Systemic absorption and central nervous system (CNS) penetration of timolol drops are a well-studied phenomenon, resulting in common side effects such as bradycardia, bronchospasm, fatigue, and confusion. More serious CNS side effects, such as psychosis and depression, however, are rarely attributed to eye drops. We report a case series in which patients developed visual hallucinations secondary to topical ocular timolol use. This study is a case series and review of the literature. Four patients with glaucoma developed visual hallucinations while using topical timolol. The patients were all elderly, caucasian females with associated CNS pathology. All patients had resolution of symptoms upon discontinuation and a positive retrial test to confirm the association. The rarity of this side effect and its anecdotal predilection for elderly, caucasian females with underlying neurological dysfunction, may involve a yet unknown predisposition or hypersensitivity to beta blocker action, such as blood brain barrier disruption leading to increased susceptibility to the medication. This case series highlights an important, although rare, side effect of this medication which clinicians should be aware of especially when using it in elderly patients who may have coexisting CNS pathology. It is important that this side effect be recognized and appropriately managed to prevent otherwise unnecessary investigations and treatment.

  8. Anesthesia for left ventricular assist device insertion: a case series and review.

    Science.gov (United States)

    Broussard, David; Donaldson, Emilie; Falterman, Jason; Bates, Michael

    2011-01-01

    From October 2008 to June 2010, a total of 42 patients had the HeartMate II left ventricular assist device inserted surgically at Ochsner Medical Center in New Orleans, LA. A retrospective electronic record review was conducted on this series of patients to analyze elements of perioperative anesthetic care, including general anesthetic care, echocardiographic considerations, and blood product usage. Etomidate was used to induce anesthesia for 34 of 42 patients (81%) in this series, with an average dose of 16.5 mg (±6 mg). The average intraoperative fentanyl dose was 1,318 µg (±631 µg). On average, patients were extubated 91 hours (±72 hours) after arrival to the intensive care unit and left on day 9 (±5 days). The average left ventricular ejection fraction of the patients in this series was 13% (±5%). Sixteen patients were evaluated as having severe right-heart dysfunction preoperatively. Two of 42 patients required surgical closure of echocardiographically identified patent foramen ovale. Twelve of 42 patients underwent surgical correction of tricuspid regurgitation. On average, 3 units (±2.6 units) of fresh frozen plasma were transfused intraoperatively and 10 units postoperatively. Intraoperative red blood cell usage averaged 1.1 units (maximum, 7 units), with an average 9.3 units administered in the first 48 hours postoperatively.

  9. Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series

    Science.gov (United States)

    Lei, Xiang; Chen, Jing; Ren, Jingtian; Li, Yan; Zhai, Jingbo; Mu, Wei; Zhang, Li; Zheng, Wenke; Tian, Guihua; Shang, Hongcai

    2015-01-01

    Objective. To summarize the characteristics and analysis of relevant factors and to give references for prevention and further study of liver damage associated with Polygonum multiflorum Thunb. (HSW), we provide a systematic review of case reports and case series about liver damage associated with HSW. Methods. An extensive search of 6 medical databases was performed up to June 2014. Case reports and case series involving liver damage associated with HSW were included. Results. This review covers a total of 450 cases in 76 articles. HSW types included raw and processed HSW decoction pieces and many Chinese patent medicines that contain HSW. Symptoms of liver damage occur mostly a month or so after taking the medicine, mainly including jaundice, fatigue, anorexia, and yellow or tawny urine. Of the 450 patients, two cases who received liver transplantation and seven who died, the remaining 441 cases recovered or had liver function improvement after discontinuing HSW products and conservative care. Conclusion. HSW causes liver toxicity and may cause liver damage in different degrees and even lead to death; most of them are much related to long-term and overdose of drugs. Liver damage associated with HSW is reversible, and, after active treatment, the majority can be cured. People should be alert to liver damage when taking HSW preparations. PMID:25648693

  10. Liver Damage Associated with Polygonum multiflorum Thunb.: A Systematic Review of Case Reports and Case Series

    Directory of Open Access Journals (Sweden)

    Xiang Lei

    2015-01-01

    Full Text Available Objective. To summarize the characteristics and analysis of relevant factors and to give references for prevention and further study of liver damage associated with Polygonum multiflorum Thunb. (HSW, we provide a systematic review of case reports and case series about liver damage associated with HSW. Methods. An extensive search of 6 medical databases was performed up to June 2014. Case reports and case series involving liver damage associated with HSW were included. Results. This review covers a total of 450 cases in 76 articles. HSW types included raw and processed HSW decoction pieces and many Chinese patent medicines that contain HSW. Symptoms of liver damage occur mostly a month or so after taking the medicine, mainly including jaundice, fatigue, anorexia, and yellow or tawny urine. Of the 450 patients, two cases who received liver transplantation and seven who died, the remaining 441 cases recovered or had liver function improvement after discontinuing HSW products and conservative care. Conclusion. HSW causes liver toxicity and may cause liver damage in different degrees and even lead to death; most of them are much related to long-term and overdose of drugs. Liver damage associated with HSW is reversible, and, after active treatment, the majority can be cured. People should be alert to liver damage when taking HSW preparations.

  11. Educational Scholarship and Technology: Resources for a Changing Undergraduate Medical Education Curriculum.

    Science.gov (United States)

    Kyle, Brandon N; Corral, Irma; John, Nadyah Janine; Shelton, P G

    2017-06-01

    Returning to the original emphasis of higher education, universities have increasingly recognized the value and scholarship of teaching, and medical schools have been part of this educational scholarship movement. At the same time, the preferred learning styles of a new generation of medical students and advancements in technology have driven a need to incorporate technology into psychiatry undergraduate medical education (UGME). Educators need to understand how to find, access, and utilize such educational technology. This article provides a brief historical context for the return to education as scholarship, along with a discussion of some of the advantages to this approach, as well as several recent examples. Next, the educational needs of the current generation of medical students, particularly their preference to have technology incorporated into their education, will be discussed. Following this, we briefly review the educational scholarship of two newer approaches to psychiatry UGME that incorporate technology. We also offer the reader some resources for accessing up-to-date educational scholarship for psychiatry UGME, many of which take advantage of technology themselves. We conclude by discussing the need for promotion of educational scholarship.

  12. Evaluation of Streptococcus pneumoniae in bile samples: A case series review.

    Science.gov (United States)

    Itoh, Naoya; Kawamura, Ichiro; Tsukahara, Mika; Mori, Keita; Kurai, Hanako

    2016-06-01

    Although Streptococcus pneumoniae is an important pathogen of humans, pneumococcal cholangitis is rare because of the rapid autolysis of S. pneumoniae. The aim of this case series was to review patients with bile cultures positive for S. pneumoniae. This study was a single center retrospective case series review of patients with S. pneumoniae in their bile at a tertiary-care cancer center between September 2002 and August 2015. Subjects consisted of all patients in whom S. pneumoniae was isolated in their bile during the study period. Bile specimens for culture were obtained from biliary drainage procedures such as endoscopic retrograde biliary drainage, endoscopic nasobiliary drainage, and percutaneous transhepatic biliary drainage. There were 20 patients with bile cultures positive for S. pneumoniae during the study period. All patients presented with extrahepatic obstructive jaundice due to hepatopancreatobiliary tumors. Nineteen of 20 patients underwent the placement of plastic intrabiliary tubes. The mean time between the first-time drainage and the positive culture was 26 days (range 0-313 days). Although 12 of 20 patients met our definition of cholangitis, 5 were clinically treated with antibiotics based on a physician's assessment of whether there was a true infection. The present study is the largest case series of patients with S. pneumoniae in their bile. Based on our findings, the isolation of S. pneumoniae from bile may be attributed to the placement of biliary drainage devices. Copyright © 2016 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  13. Defining and assessing the scholarship of teaching in nursing.

    Science.gov (United States)

    Oermann, Marilyn H

    2014-01-01

    Scholarship of teaching is inquiry about learning and teaching-asking questions about what works best and why and seeking answers through a systematic approach. This article provides a broad view of the scholarship of teaching in nursing, which captures the richness and breadth of our scholarship as nurse educators. The article suggests strategies for transforming teaching into scholarship and products of the scholarship of teaching for performance assessment. Copyright © 2014 Elsevier Inc. All rights reserved.

  14. Scholarship as a Way of Life

    DEFF Research Database (Denmark)

    Eskildsen, Kasper Risbjerg

    2016-01-01

    human beings. During the late nineteenth and early twentieth centuries, the rise of Big Humanities questioned this moral purpose. However, Big Humanities also reemphasized the importance of epistemic virtues for scholarship. The language of epistemic virtues helped scholars create new communities...... of learning and scholarship. Within these communities, the language of virtues established common standards of collaboration and granted scholars a sense of purpose. Many of these scholars also continued to associate epistemic virtues with moral virtues....

  15. Pediatric cavernous sinus thrombosis: A case series and review of the literature.

    Science.gov (United States)

    Smith, Douglas M; Vossough, Arastoo; Vorona, Gregory A; Beslow, Lauren A; Ichord, Rebecca N; Licht, Daniel J

    2015-09-01

    To describe clinical characteristics, imaging findings, morbidity, and mortality in a single-center cohort of 12 pediatric cavernous sinus thrombosis cases and to review all cases available in recent English literature. Clinical data and radiographic studies on 12 cases from our institution were analyzed retrospectively. A literature search and review was conducted, with additional cases pooled with the new cohort for an aggregate analysis. Twelve cases of cavernous sinus thrombosis in children from the Children's Hospital of Philadelphia between January 1, 2000, and December 31, 2013, were reviewed. All patients survived to discharge; 3 of 12 (25%) experienced neurologic morbidity. Contrast-enhanced MRI and contrast-enhanced head CT were 100% sensitive for detecting cavernous sinus thrombosis, while noncontrast time-of-flight magnetic resonance venography (TOF MRV) and noncontrast head CT were 0% sensitive. Literature review produced an additional 40 cases, and the aggregate mortality rate was 4 of 52 (8%) and morbidity rate was 10 of 40 (25%). Outcomes did not vary by treatment or with unilateral vs bilateral cavernous sinus involvement. There was a trend toward worse outcomes with fungal infections. Our case series demonstrates low morbidity and mortality with early, aggressive surgical, antimicrobial, and anticoagulation therapies. Although anticoagulation and surgery were not associated with significantly different outcomes, more study is needed. © 2015 American Academy of Neurology.

  16. A senior scholars forum can enhance the scholarship process.

    Science.gov (United States)

    Schneider, Jeffrey I; Mitchell, Patricia M; Wilcox, Allison R; Linden, Judith A; Mycyk, Mark B

    2014-01-01

    The purpose of our study was to evaluate the educational value of an annual Senior Scholars Forum (SSF) of graduating Emergency Medicine resident participants and attendees. This study was conducted at an urban academic medical center with a PGY1-4 year residency program. After completion of the 2nd annual SSF, a web-based survey instrument was sent to all resident and faculty attendees. The instrument was a 3-part tool adapted from previous studies on postgraduate scholarship. Data were analyzed using descriptive statistics. Forty-two of the 44 (95%) attendees completed the survey, including 100% of the PGY4 resident presenters. Prior to the SSF, 52% of respondents did not have a full understanding of senior scholarly activities. After the SSF, 67% reported an improved understanding and 88% had a better understanding of the scope of potential scholarly projects. Sixty-four percent reported the SSF introduced them to departmental resources available for completion of their own scholarly projects, and 69% would have liked to have heard the lessons communicated earlier in residency. Most (79%) agreed the SSF demonstrated the value of communal scholarly activities. Most senior residents (67%) felt most of the department would not know about their scholarship if they had not participated in the SSF. Our innovative SSF enhanced the scholarship process by allowing graduating senior residents an opportunity to share their scholarly productivity with a larger audience, provided attendees critical insights into the process of scholarship, and encouraged communal learning. Because the Accreditation Council for Graduate Medical Education and Residency Review Committee require all residents to participate in scholarly activity, other training programs may benefit from a similar educational experience.

  17. Infarction of papillary thyroid carcinoma after fine-needle aspiration: case series and review of literature.

    Science.gov (United States)

    Liu, Yuan F; Ahmed, Sameer; Bhuta, Sunita; Sercarz, Joel A

    2014-01-01

    Although infarction after fine-needle aspiration (FNA) is a rare occurrence, it is a known phenomenon that may lead to difficulties in interpretation for pathologists and in decision-making for head and neck surgeons. To characterize our experience with infarction in papillary thyroid carcinomas (PTCs) after FNA and review existing cases of infarcted PTCs in the literature to better understand this phenomenon. This was a retrospective case series and review of literature at a tertiary medical center (University of California, Los Angeles [UCLA], Medical Center). All patients who had a surgical pathologic diagnosis of infarcted PTC and who underwent FNA prior to surgery at UCLA from June 2006 to June 2012 were identified. There were 620 cases of PTC and 12 cases of infarcted PTC. Demographic data, FNA cytologic findings, and surgical pathologic data were gathered for each patient. A comprehensive literature search for infarcted PTC was performed. Twelve cases of infarcted PTC were found in a total of 620 cases of PTC (1.9%). The mean (SD) time interval between the last FNA and surgery was 52 (35) days (range, 13-133 days). All patients received a diagnosis of infarcted PTC after thyroidectomy was performed. Focal infarction was found in 4 patients (33%), and near-total infarction was found in 8 patients (67%). Five patients (47%) had the follicular variant of PTC, making it the most common subtype in our series. A thorough literature search yielded 11 articles reporting a total of 26 cases of infarcted PTC after FNA. To our knowledge, our case series on infarcted PTC is the largest reported series in the literature. Although infarction of PTC after FNA occurs infrequently, it may lead to difficulties in histologic diagnosis. Awareness of this phenomenon and its histologic associations, along with careful reevaluation of the FNA and surgical specimens, is important for appropriate diagnosis and subsequent treatment. At this point, infarction in PTC should not alarm a

  18. Lipomas of the Brachial Plexus: A Case Series and Review of the Literature.

    Science.gov (United States)

    Graf, Alexander; Yang, Kai; King, David; Dzwierzynski, William; Sanger, James; Hettinger, Patrick

    2017-10-01

    Lipomas are common benign tumors. When they develop in proximity to peripheral nerves, they can cause neurologic symptoms secondary to mass effect. Previous reports have shown symptom resolution after removal of lipomas compressing various upper extremity peripheral nerves. However, brachial plexus lipomas are relatively rare. Our multidisciplinary experience with brachial plexus lipoma resection is reviewed in the largest case series to date. A retrospective chart review of all patients undergoing resection of brachial plexus lipomatous tumors between 2006 and 2016 was performed. Patient demographic data, diagnostic imaging, clinical presentation, operative details, surgical pathology, and clinical outcomes were reviewed. Twelve brachial plexus lipomatous tumors were resected in 11 patients: 10 lipomas, 1 hibernoma, and 1 atypical lipomatous tumor. The most common tumor location was supraclavicular (50%), followed by axillary (42%), and proximal medial arm (8%). The most common brachial plexus segment involved was the upper trunk (50%), followed by posterior cord (25%), lateral pectoral nerve (8%), lower trunk (8%), and proximal median nerve (8%). Most patients presented with an enlarging painless mass (58%). Of the patients who presented with neurologic symptoms, symptoms resolved in the majority (80%). Brachial plexus lipomas are rare causes of compression neuropathy in the upper extremity. Careful resection and knowledge of brachial plexus anatomy, which may be distorted by the tumor, are critical to achieving a successful surgical outcome with predictable symptom resolution. Finally, surveillance magnetic resonance imaging may be warranted for atypical lesions.

  19. Code, Scholarship, and Criticism : When is Coding Scholarship and When is it Not?

    NARCIS (Netherlands)

    van Zundert, Joris J.; Haentjens Dekker, R.

    2017-01-01

    What is the scholarly nature of code and how do we evaluate the scholarship involved with coding? Our claim is that the humanities need an urgent answer to these questions given the increasing softwarization of both society and scholarship that pushes the boundaries of the methods and objects of

  20. Networked Participatory Scholarship: Emergent Techno-Cultural Pressures toward Open and Digital Scholarship in Online Networks

    Science.gov (United States)

    Veletsianos, George; Kimmons, Royce

    2012-01-01

    We examine the relationship between scholarly practice and participatory technologies and explore how such technologies invite and reflect the emergence of a new form of scholarship that we call "Networked Participatory Scholarship": scholars' participation in online social networks to share, reflect upon, critique, improve, validate, and…

  1. Adverse events associated with yoga: a systematic review of published case reports and case series.

    Science.gov (United States)

    Cramer, Holger; Krucoff, Carol; Dobos, Gustav

    2013-01-01

    While yoga is gaining increased popularity in North America and Europe, its safety has been questioned in the lay press. The aim of this systematic review was to assess published case reports and case series on adverse events associated with yoga. Medline/Pubmed, Scopus, CAMBase, IndMed and the Cases Database were screened through February 2013; and 35 case reports and 2 case series reporting a total of 76 cases were included. Ten cases had medical preconditions, mainly glaucoma and osteopenia. Pranayama, hatha yoga, and Bikram yoga were the most common yoga practices; headstand, shoulder stand, lotus position, and forceful breathing were the most common yoga postures and breathing techniques cited. Twenty-seven adverse events (35.5%) affected the musculoskeletal system; 14 (18.4%) the nervous system; and 9 (11.8%) the eyes. Fifteen cases (19.7%) reached full recovery; 9 cases (11.3%) partial recovery; 1 case (1.3%) no recovery; and 1 case (1.3%) died. As any other physical or mental practice, yoga should be practiced carefully under the guidance of a qualified instructor. Beginners should avoid extreme practices such as headstand, lotus position and forceful breathing. Individuals with medical preconditions should work with their physician and yoga teacher to appropriately adapt postures; patients with glaucoma should avoid inversions and patients with compromised bone should avoid forceful yoga practices.

  2. Adverse events associated with yoga: a systematic review of published case reports and case series.

    Directory of Open Access Journals (Sweden)

    Holger Cramer

    Full Text Available While yoga is gaining increased popularity in North America and Europe, its safety has been questioned in the lay press. The aim of this systematic review was to assess published case reports and case series on adverse events associated with yoga. Medline/Pubmed, Scopus, CAMBase, IndMed and the Cases Database were screened through February 2013; and 35 case reports and 2 case series reporting a total of 76 cases were included. Ten cases had medical preconditions, mainly glaucoma and osteopenia. Pranayama, hatha yoga, and Bikram yoga were the most common yoga practices; headstand, shoulder stand, lotus position, and forceful breathing were the most common yoga postures and breathing techniques cited. Twenty-seven adverse events (35.5% affected the musculoskeletal system; 14 (18.4% the nervous system; and 9 (11.8% the eyes. Fifteen cases (19.7% reached full recovery; 9 cases (11.3% partial recovery; 1 case (1.3% no recovery; and 1 case (1.3% died. As any other physical or mental practice, yoga should be practiced carefully under the guidance of a qualified instructor. Beginners should avoid extreme practices such as headstand, lotus position and forceful breathing. Individuals with medical preconditions should work with their physician and yoga teacher to appropriately adapt postures; patients with glaucoma should avoid inversions and patients with compromised bone should avoid forceful yoga practices.

  3. Split mouth de-epithelization techniques for gingival depigmentation: A case series and review of literature.

    Science.gov (United States)

    Kathariya, Rahul; Pradeep, A R

    2011-04-01

    Gingival melanin pigmentation occurs in all races of mankind. Although clinical melanin pigmentation does neither present itself as a medical problem nor a disease entity, it is a major esthetic concern for many people, especially Asians. Esthetic gingival depigmentation procedures can be performed in such patients with excellent results. This case series presents a split mouth de-epithelization procedure using popular surgical techniques such as scalpel, bur abrasion or electrosurgery. These techniques were successfully used to treat gingival hyperpigmentation. Although we found that electrosurgery increased the efficacy of our work, giving a cleaner and neater work field, it required a lot of precision. In contrast, scalpel de-epithelization was easy and technique-friendly, giving excellent results and patient satisfaction. However, the cases are being followed-up to study the factors affecting the rate and length of time required for repigmentation and to study the repigmentation patterns. This case series also reviews the advantages and disadvantages of various techniques available for depigmentation, and reiterates that the scalpel technique still serves as a gold standard for depigmentation.

  4. [Therapeutic options for portal hypertensive biliopathy: case series and literature review].

    Science.gov (United States)

    Aguilar-Olivos, Nancy Edith; de León-Monterroso, José Luis; Avila-Escobedo, Lourdes; López-Méndez, Eric

    2014-01-01

    Portal hypertensive biliopathy is an underdiagnosed condition because only some patients have symptoms. The major clinical manifestations include cholestasis and cholangitis. The aim of this study is to present a series of cases evaluated, treated and followed at a tertiary-care public institution. Four patients with portal hypertensive biliopathy were exposed to different therapeutic approaches focused on the management of portal hypertension and biliary decompression. They were followed for ~5 years. Three cases achieved a favorable outcome with symptom remission, but one patient died while attempting dilatation of the bile duct. Finally, we carried out a literature review about actual portal hypertensive biliopathy therapeutics. There is currently no consensus on the optimal treatment for this condition. The goal is to decompress the biliary tree. Each case should be individually evaluated to choose the best treatment option.

  5. Adverse effects of aromatherapy: a systematic review of case reports and case series.

    Science.gov (United States)

    Posadzki, Paul; Alotaibi, Amani; Ernst, Edzard

    2012-01-01

    This systematic review was aimed at critically evaluating the evidence regarding the adverse effects associated with aromatherapy. Five electronic databases were searched to identify all relevant case reports and case series. Forty two primary reports met our inclusion criteria. In total, 71 patients experienced adverse effects of aromatherapy. Adverse effects ranged from mild to severe and included one fatality. The most common adverse effect was dermatitis. Lavender, peppermint, tea tree oil and ylang-ylang were the most common essential oils responsible for adverse effects. Aromatherapy has the potential to cause adverse effects some of which are serious. Their frequency remains unknown. Lack of sufficiently convincing evidence regarding the effectiveness of aromatherapy combined with its potential to cause adverse effects questions the usefulness of this modality in any condition.

  6. Male lupus: a diagnosis often delayed--a case series and review of the literature.

    LENUS (Irish Health Repository)

    Ambrose, N L

    2012-02-01

    INTRODUCTION: Systemic lupus erythematosus (SLE) is an auto-immune disease that is characterised by autoantibody production. Male lupus is rare, apart from at either end of the age spectrum. AIM: In this series, we review the histories of six male lupus patients attending our service. RESULTS: Our patients presented in middle age and tended to develop haematological abnormalities, renal involvement and neurological manifestations which preceded the onset of their skin and joint complaints. Our patients accrued damage rapidly and overall did badly. They tended to respond sub-optimally to standard treatments. These cases highlight the need an increased awareness that male SLE patients present with a wide variety of symptoms, and that they accrue damage quickly. There is a need for timely diagnosis and appropriate initiation of treatment. This may help avoid preventable organ damage and increase the survival of men with SLE.

  7. Natural-Series Radionuclides in Traditional Aboriginal Foods in Tropical Northern Australia: A Review

    Directory of Open Access Journals (Sweden)

    Paul Martin

    2004-01-01

    Full Text Available This paper gives a review of available information on natural-series radionuclides in traditional Aboriginal foods of northern Australia. Research on this topic has been carried out primarily for radiological impact assessment purposes in relation to uranium mining activities in the region. Many of the studies have concentrated on providing purely concentration data or concentration ratios, although more detailed uptake studies have been undertaken for freshwater mussels, turtles, and water lilies. The most-studied radionuclides are 238U and 226Ra. However, dose estimates based on current data highlight the importance of 210Po, particularly for the natural (nonmining-related dose. Data on uptake by terrestrial flora and fauna are scarce in comparison with aquatic organisms, and this knowledge gap will need to be addressed in relation to planning for uranium minesite rehabilitation.

  8. Total Contact Cast Use in Patients With Peripheral Arterial Disease: A Case Series and Systematic Review.

    Science.gov (United States)

    Tickner, Anthony; Klinghard, Cheri; Arnold, Jonathan F; Marmolejo, Valerie

    2018-02-01

    As the majority of diabetic foot ulcerations (DFUs) occur on the plantar foot, excessive pressure is a major contributing factor to delayed healing. The gold standard for offloading is the total contact cast (TCC); yet, TCC use is contraindicated in patients with ischemia. Lower extremity ischemia typically presents in the more severe end stages of peripheral arterial disease (PAD). As PAD exists on a severity spectrum from mild to severe, designation of a clear cutoff where TCC use is an absolute contraindication would assist those who treat DFUs on a daily basis. The aim of this study is to determine if a potential cutoff value for PAD where TCC use would be an absolute contraindication could be ascertained from a retrospective case series and a systematic literature review of patients with PAD in which treatment included TCC use. A retrospective cases series and systematic review of patients with mild to moderate PAD treated with a TCC was performed. All reports of TCC use in patients with PAD and a neuropathic ulceration that included results of noninvasive vascular studies were included. Results suggested that TCC use is a viable treatment modality for pressure-related DFUs in patients with an ankle pressure ≥ 80 mm Hg, a toe pressure ≥ 74 mm Hg, an ankle-brachial index ≥ 0.55, or a toe-brachial index ≥ 0.55. Vascular evaluation, individual risk/benefit analysis, close follow-up, and patient education are essential components of TCC use in these patients. Repeat vascular evaluation is recommended if the wound fails to progress towards resolution with TCC use.

  9. Disseminating sexually transmitted infections diagnostics information: the SDI web publication review series.

    Science.gov (United States)

    Kuypers, J; Tam, M R; Holmes, K K; Peeling, R W

    2006-12-01

    The World Health Organization Sexually Transmitted Diseases Diagnostics Initiative (SDI) website publication review seeks to provide health care providers in all geographic and economic settings with timely, critical, and concise information concerning new developments in laboratory and field diagnosis of sexually transmitted infections (STI). Since 2003, the website (www.who.int/std_diagnostics/literature_reviews) has disseminated information in the form of annotated abstracts and commentaries on articles covering studies of STI laboratory-based and rapid assays that are commercially available or under development. Articles identified through searches of PubMed, specific journals, and by referrals from Editorial Board members are selected for inclusion if they meet pre-specified criteria. The objectives, methods, results, and conclusions for each article are summarised and board members are invited to prepare commentaries addressing study design and applicability of findings to end users. Currently, 91 STI diagnostics experts from 17 countries on six continents serve on the Editorial Board. Twelve quarterly issues have been posted that include summaries of 214 original and 17 review articles published from January 2002 through March 2005, with expert commentaries on 153 articles. Interest in the site has increased every year. In 2005, over 36 700 unique visitors from more than 100 countries viewed over 75,000 pages of information. The SDI Publication Review series has the potential to contribute to SDI's goal of improving care for patients with STI by increasing knowledge and awareness of STI diagnostics. Given the proliferation of internet-based STI testing services, this website may be broadened to meet the needs of a wider range of users.

  10. Importance of neoadjuvant chemotherapy in olfactory neuroblastoma treatment: Series report and literature review.

    Science.gov (United States)

    Bartel, Ricardo; Gonzalez-Compta, Xavier; Cisa, Enric; Cruellas, Francesc; Torres, Alberto; Rovira, Aleix; Manos, Manel

    2017-10-20

    Olfactory neuroblastoma (ONB) is a rare entity that constitutes less than 5% of nasosinusal malignancies. Mainstream treatment consists in surgical resection+/-adjuvant radiotherapy. By exposing results observed with apparition of new therapeutic options as neoadjuvant chemotherapy, the objective is to evaluate a series and a review of the current literature. A retrospective review was conducted including patients diagnosed and followed-up for ONB from 2008 to 2015 in our institution. 9 patients were included. Mean follow-up of 52.5 months (range 10-107). Kadish stage: A, 1 patient (11.1%) treated with endoscopic surgery; B, 2 patients (22.2%) treated with endoscopic surgery (one of them received adjuvant radiotherapy); C, 6 patients (66.7%), 4 patients presented intracranial extension and were treated with neoadjuvant chemotherapy followed by surgery and radiotherapy. The other 2 patients presented isolated orbital extension, treated with radical surgery (endoscopic or craniofacial resection) plus radiotherapy. The 5-year disease free and overall survival observed was 88.9%. Neoadjuvant chemotherapy could be an effective treatment for tumor reduction, improving surgical resection and reducing its complications. Copyright © 2017 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Cirugía de Cabeza y Cuello. All rights reserved.

  11. 46 XX karyotype during male fertility evaluation; case series and literature review.

    Science.gov (United States)

    Majzoub, Ahmad; Arafa, Mohamed; Starks, Christopher; Elbardisi, Haitham; Al Said, Sami; Sabanegh, Edmund

    2017-01-01

    Forty-six XX disorder of sex development is an uncommon medical condition observed at times during the evaluation of a man's fertility. The following is a case series and literature review of phenotypically normal men diagnosed with this karyotype. Our goal is to comprehend the patients' clinical presentation as well as their laboratory results aiming to explore options available for their management. A formal literature review through PubMed and MEDLINE databases was performed using "46 XX man" as a word search. A total of 55 patients, including those conveyed in this article were diagnosed with a 46 XX karyotype during their fertility evaluation. The patients' mean age ± s.d. was 34 ± 10 years and their mean height ± s.d. was 166 ± 6.5 cm. Overall, they presented with hypergonadotropic hypogonadism. Sexual dysfunction, reduced hair distribution, and gynecomastia were reported in 20% (4/20), 25.8% (8/31), and 42% (13/31) of the patients, respectively. The SRY gene was detected in 36 (83.7%) and was absent in the remaining seven (16.3%) patients. We found that a multidisciplinary approach to management is preferred in 46 XX patients. Screening for remnants of the mullerian ducts and for malignant transformation in dysgenetic gonads is imperative. Hypogonadism should be addressed, while fertility options are in vitro fertilization with donor sperm or adoption.

  12. Immunology in clinic review series; focus on autoinflammatory diseases: role of inflammasomes in autoinflammatory syndromes.

    Science.gov (United States)

    Ozkurede, V U; Franchi, L

    2012-03-01

    OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases. Autoinflammatory syndromes are disorders characterized by the hyperactivation of the innate immune system in the absence of microbial infection or autoantibody production. Some autoinflammatory syndromes are associated with recurrent episodes of fever and systemic inflammation that are caused by dysregulated activation of inflammasomes, molecular platforms responsible for the activation of caspase-1 and the production of interleukin (IL)-1β. In this review we will discuss the role of IL-1β and the inflammasomes in host defence and how mutations of two genes, NLRP3 and PYRIN, leads to the autoinflammatory syndromes, cryopyrin-associated periodic syndromes (CAPS) and familial Mediterranean fever (FMF). Both CAPS and FMF are characterized by increased inflammasome activity and overproduction of IL-1β which is ultimately responsible for disease manifestations. Importantly, understanding the molecular mechanisms of these syndromes has led to effective treatment for these rare diseases with biological drugs that target IL-1β-mediated signalling. © 2011 The Authors. Clinical and Experimental Immunology © 2011 British Society for Immunology.

  13. Immunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activation.

    Science.gov (United States)

    Mankan, A K; Kubarenko, A; Hornung, V

    2012-03-01

    OTHER THEMES PUBLISHED IN THIS IMMUNOLOGY IN THE CLINIC REVIEW SERIES Allergy, Host Responses, Cancer, Type 1 diabetes and viruses, Metabolic diseases. Initiation of a successful immune response requires a working set of sensors that detect any noxious agent within the cellular microenvironment and molecular platforms that process this signal to trigger an appropriate effector response. Pattern recognition receptors can engage different signalling cascades that lead to proinflammatory gene expression. At the same time, transcription-independent events such as activation of proteases and/or phagocytosis are also initiated. The inflammasome pathway constitutes a signalling platform that leads to the activation of so-called inflammatory caspases, most notably caspase-1, which plays a pivotal role in the cleavage and thus maturation of proinflammatory cytokines, but also in the induction of pyroptosis, a special type of cell death. In this review we elaborate on the currently known inflammasome complexes with a special focus on the mechanism behind their activation. Understanding these mechanisms could provide important information regarding the potential signalling nodes that might be targeted for therapeutic intervention. © 2011 The Authors. Clinical and Experimental Immunology © 2011 British Society for Immunology.

  14. Anterior ischemic optic neuropathy and hematologic malignancy: a systematic review of case reports and case series.

    Science.gov (United States)

    Sousa, David Cordeiro; Rodrigues, Filipe Brogueira; Duarte, Gonçalo; Campos, Fátima; Pinto, Filomena; Vaz-Carneiro, A

    2016-12-01

    Demographic and clinical characteristics associated with nonarteritic anterior ischemic optic neuropathy (NAION) are well described. Patients with hematologic neoplasms may share some of these characteristics, and it may be useful clinically to better understand this set of patients. Our objective is to review systematically the characteristics of patients with both hematologic malignancies and NAION. Systematic review. Patients with NAION diagnosis related in time to a hematologic neoplasm. Data sources for the study included MEDLINE, Web of Science, LILACS, SciELO, and OpenGrey. The study eligibility criteria included case reports and case series. We found 261 records, with 15 studies included plus our case report. A total of 19 patients (8 female) with mean age of 54.6 years (range, 12-87) were analyzed: 37% (7) non-Hodgkin lymphoma; 26% (5) myeloproliferative neoplasms; 21% (4) myelodysplasia; 16% (3) leukemias. The limitations included verification bias, inability to test statistical association between NAION and hematologic neoplasms, the small number of cases, and confounding factors related to medical history and specific interventions in each case limited the robustness of our conclusions. Our results identified the characteristics of patients with NAION and hematologic neoplasms related in time. Additional observational studies may enlighten the importance of looking for evidence of an occult neoplastic disorder in patients presenting with NAION. A prompt diagnosis would be of invaluable significance for the best management, in terms of follow-up and therapeutics. Copyright © 2016 Canadian Ophthalmological Society. Published by Elsevier Inc. All rights reserved.

  15. Tattooing and psoriasis: a case series and review of the literature.

    Science.gov (United States)

    Kluger, Nicolas; Estève, Eric; Fouéré, Sébastien; Dupuis-Fourdan, Florence; Jegou, Marie-Hélène; Lévy-Rameau, Chantal

    2017-08-01

    Koebner phenomenon (KP) affects from a quarter to a third of the patients with psoriasis and can occur on tattoos MATERIAL AND METHODS: We retrospectively reviewed a case series of seven tattooed patients with an isomorphic response on their tattoos or partial psoriasis patches on their tattoos. We collected the demographic data, the past history of psoriasis, the clinical presentation, and the outcomes. We also performed a review of the literature. We tried to classify the different clinical profile of KP/psoriasis on tattoos accordingly. Six men and one woman with a median age of 36 ± 6.4 years old were included. Five disclosed a KP in a recent tattoo within days to 1 month after its completion. Fifteen additional cases were collected from the literature (8 men, median age 22 ± 8.2 years old). The delay of psoriasis flare-up after tattooing was rather short, from a few weeks to several months. We found a high variability in the clinical presentation with five clinical subtypes/profiles of psoriasis on tattoos. A possible confusion between "genuine" KP on tattoos and the coincidental occurrence of psoriasis patches on tattoos is possible in some cases of the literature. Patients were mainly managed locally, rarely by systemic treatments or biologics. Koebner phenomenon on tattoos may occur in patients with psoriasis under various forms. The evolution is benign, and psoriasis is not a contraindication for tattooing, but patients need proper counseling before getting tattooed. © 2017 The International Society of Dermatology.

  16. Patient outcomes following lower leg major amputations for peripheral arterial disease: A series review.

    Science.gov (United States)

    Monaro, Susan; West, Sandra; Gullick, Janice

    2017-06-01

    Despite improvements in revascularization, major amputation remains a significant part of the case-mix in vascular surgical units. These patients tend to be elderly with complex pathology, resulting in poor outcomes and longer lengths of stay (LOS). This series review provides a description of the patient complexities and outcomes in an Australian cohort undergoing major lower limb amputation for peripheral arterial disease. Medical records coded for major amputation between July 2012 and June 2013 in an Australian government funded, tertiary hospital were retrospectively reviewed and descriptively analyzed. Twenty-five patients had 29 major amputations including four conversions from below to above knee. Seventeen had multiple vascular procedures before amputation. The average LOS exceeded the national target, and there was substantial morbidity and 30-day mortality. Major amputation continues to present challenges because of patient frailty and the high rate of complications. These issues need to be considered in a robust care planning framework that includes consideration of cognitive decline and other markers of frailty. Opportunities to optimize the physical condition of these patients and to reduce delays in proceeding to surgery require further investigation. Copyright © 2016 Society for Vascular Nursing, Inc. All rights reserved.

  17. Ganglion cysts of the cruciate ligaments: a series of 31 cases and review of the literature

    Directory of Open Access Journals (Sweden)

    Mao Yongtao

    2012-08-01

    Full Text Available Abstract Background A case series for ganglion cyst of the cruciate ligament with MRI findings, clinical presentation, and management options along with review of literature is presented. Methods Of 8663 consecutive patients referred for knee MR imaging, 31 were diagnosed with ganglion cysts of the cruciate ligaments, including 21 men and 10 women of ages 12 to 73 years (mean: 37. A review of charts revealed that knee pain was the chief complaint in all cases. Arthroscopic debridement of ganglion cyst was performed in 11 patients. Results MRI proved to be a valuable tool in diagnosing and deciding management of these cases. All 11 patients who underwent arthroscopic treatment were symptom-free on a minimum follow-of one year. Conclusion Cyst formation associated with cruciate ligament of the knee is an infrequent cause of knee pain. MR imaging was important in confirming the cyst lesions and provided useful information prior to arthroscopy. Arthroscopic debridement of ganglion cyst produced excellent outcome without recurrence. This study describes the pertinent MRI and intraoperative findings of ganglion cyst.

  18. Keeping pace with the media; Giant Hogweed burns - A case series and comprehensive review.

    Science.gov (United States)

    Baker, Benjamin G; Bedford, James; Kanitkar, Suryakant

    2017-08-01

    Phytophotodermatitis is almost exclusively reported in the dermatological literature, but may progress to a chemical burn. There has been widespread media reporting during the summer of 2015 of burns caused by giant hogweed. However, there is a lack of awareness of this mechanism of injury amongst the burn multidisciplinary team, and there have been no published articles in the surgical literature regarding plant burns, other than sporadic case reports, for 20 years. We present a comprehensive review of plant burns and three cases from our adult and paediatric Burn Centres of burns caused by giant hogweed. Accurate diagnosis is straightforward with a detailed history and is important to prompt appropriate treatment, and prevent a misdiagnosis of non-accidental injury. This review and case series are timely to raise awareness of phytophotodermatitis and burns caused by plants to burns multidisciplinary teams. Prospective studies are warranted to assess the efficacy of topical treatments and surgical management. Copyright © 2016 Elsevier Ltd and ISBI. All rights reserved.

  19. Methods, applications, interpretations and challenges of interrupted time series (ITS) data: protocol for a scoping review

    Science.gov (United States)

    Ewusie, Joycelyne E; Blondal, Erik; Soobiah, Charlene; Beyene, Joseph; Thabane, Lehana; Straus, Sharon E; Hamid, Jemila S

    2017-01-01

    Objectives Interrupted time series (ITS) design involves collecting data across multiple time points before and after the implementation of an intervention to assess the effect of the intervention on an outcome. ITS designs have become increasingly common in recent times with frequent use in assessing impact of evidence implementation interventions. Several statistical methods are currently available for analysing data from ITS designs; however, there is a lack of guidance on which methods are optimal for different data types and on their implications in interpreting results. Our objective is to conduct a scoping review of existing methods for analysing ITS data, to summarise their characteristics and properties, as well as to examine how the results are reported. We also aim to identify gaps and methodological deficiencies. Methods and analysis We will search electronic databases from inception until August 2016 (eg, MEDLINE and JSTOR). Two reviewers will independently screen titles, abstracts and full-text articles and complete the data abstraction. The anticipated outcome will be a summarised description of all the methods that have been used in analysing ITS data in health research, how those methods were applied, their strengths and limitations and the transparency of interpretation/reporting of the results. We will provide summary tables of the characteristics of the included studies. We will also describe the similarities and differences of the various methods. Ethics and dissemination Ethical approval is not required for this study since we are just considering the methods used in the analysis and there will not be identifiable patient data. Results will be disseminated through open access peer-reviewed publications. PMID:28674142

  20. Methods, applications, interpretations and challenges of interrupted time series (ITS) data: protocol for a scoping review.

    Science.gov (United States)

    Ewusie, Joycelyne E; Blondal, Erik; Soobiah, Charlene; Beyene, Joseph; Thabane, Lehana; Straus, Sharon E; Hamid, Jemila S

    2017-07-02

    Interrupted time series (ITS) design involves collecting data across multiple time points before and after the implementation of an intervention to assess the effect of the intervention on an outcome. ITS designs have become increasingly common in recent times with frequent use in assessing impact of evidence implementation interventions. Several statistical methods are currently available for analysing data from ITS designs; however, there is a lack of guidance on which methods are optimal for different data types and on their implications in interpreting results. Our objective is to conduct a scoping review of existing methods for analysing ITS data, to summarise their characteristics and properties, as well as to examine how the results are reported. We also aim to identify gaps and methodological deficiencies. We will search electronic databases from inception until August 2016 (eg, MEDLINE and JSTOR). Two reviewers will independently screen titles, abstracts and full-text articles and complete the data abstraction. The anticipated outcome will be a summarised description of all the methods that have been used in analysing ITS data in health research, how those methods were applied, their strengths and limitations and the transparency of interpretation/reporting of the results. We will provide summary tables of the characteristics of the included studies. We will also describe the similarities and differences of the various methods. Ethical approval is not required for this study since we are just considering the methods used in the analysis and there will not be identifiable patient data. Results will be disseminated through open access peer-reviewed publications. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. Volterra-series-based nonlinear system modeling and its engineering applications: A state-of-the-art review

    Science.gov (United States)

    Cheng, C. M.; Peng, Z. K.; Zhang, W. M.; Meng, G.

    2017-03-01

    Nonlinear problems have drawn great interest and extensive attention from engineers, physicists and mathematicians and many other scientists because most real systems are inherently nonlinear in nature. To model and analyze nonlinear systems, many mathematical theories and methods have been developed, including Volterra series. In this paper, the basic definition of the Volterra series is recapitulated, together with some frequency domain concepts which are derived from the Volterra series, including the general frequency response function (GFRF), the nonlinear output frequency response function (NOFRF), output frequency response function (OFRF) and associated frequency response function (AFRF). The relationship between the Volterra series and other nonlinear system models and nonlinear problem solving methods are discussed, including the Taylor series, Wiener series, NARMAX model, Hammerstein model, Wiener model, Wiener-Hammerstein model, harmonic balance method, perturbation method and Adomian decomposition. The challenging problems and their state of arts in the series convergence study and the kernel identification study are comprehensively introduced. In addition, a detailed review is then given on the applications of Volterra series in mechanical engineering, aeroelasticity problem, control engineering, electronic and electrical engineering.

  2. Health Professions Education Scholarship Unit Leaders as Institutional Entrepreneurs

    NARCIS (Netherlands)

    Varpio, L.; O'Brien, B.; Durning, S.J.; Vleuten, C. van der; Gruppen, L.; Cate, O. Ten; Humphrey-Murto, S.; Irby, D.M.; Hamstra, S.J.; Hu, W.

    2017-01-01

    PURPOSE: Health professions education scholarship units (HPESUs) are organizational structures within which a group is substantively engaged in health professions education scholarship. Little research investigates the strategies employed by HPESU administrative leaders to secure and maintain HPESU

  3. The Status of Ethics Scholarship in Speech Communication Journals from 1915 to 1985.

    Science.gov (United States)

    Arnett, Ronald C.

    To examine the theoretical status of ethics scholarship and to explore the historical and present directions of ethics in human communication research, this paper reviews more than 100 articles drawn from the speech communication literature. Following a brief introduction that sets forth the criteria for article selection, the paper discusses…

  4. Marginalization of Published Scholarship on Students with Disabilities in Higher Education Journals

    Science.gov (United States)

    Pena, Edlyn Vallejo

    2014-01-01

    While numbers of students with disabilities continue to rise in postsecondary education, little is known about the extent to which the scholarship on this student population has kept pace. A critical content analysis was conducted to review articles on students with disabilities published in top-tier journals of higher education between 1990 and…

  5. Contemplating and Extending the Scholarship on Children's and Young Adult Literature

    Science.gov (United States)

    Brooks, Wanda; Cueto, Desiree

    2018-01-01

    To commemorate the 50th anniversary of the "Journal of Literacy Research," this article reviews the trajectory of a particular line of scholarship published in this journal over the past five decades. We focus on African diaspora youth literature to contemplate and extend the ways in which literacy researchers carry out textual analysis…

  6. How Course Portfolios Can Advance the Scholarship and Practice of Management Teaching

    Science.gov (United States)

    New, J. Randolph; Clawson, James G.; Coughlan, Richard S.; Hoyle, Joe Ben

    2008-01-01

    The authors believe the development, peer review, and sharing of course portfolios can significantly improve the scholarship and teaching of management. To make this case, they provide background information about course portfolios, including origins, defining features, purposes, and potential benefits. They then identify actual portfolio projects…

  7. Adult anaplastic pilocytic astrocytoma - a diagnostic challenge? A case series and literature review.

    Science.gov (United States)

    Fiechter, Michael; Hewer, Ekkehard; Knecht, Urspeter; Wiest, Roland; Beck, Jürgen; Raabe, Andreas; Oertel, Markus F

    2016-08-01

    Anaplastic pilocytic astrocytoma (APA) is an exceptionally rare type of high-grade glioma in adults. Establishing histopathological diagnosis is challenging and its clinical and radiological appearance insidious. By this case series and first literature review we investigated the various clinical, neuroradiological, and histopathological features of APA in adults. An in hospital screening of the database from the Institute of Pathology was conducted to identify cases of APA. Further, we performed a literature review in PubMed using the keywords "anaplastic/malignant/atypical AND pilocytic astrocytoma" and "anaplastic astrocytoma/glioblastoma AND Rosenthal fibers" and summarized the current knowledge about APA in adults. Over the last decade we were able to identify 3 adult patients with APA in our hospital. According to the pertinent literature, the prognosis of APA in adults (documented survival of up to 10 years) appears to be better than in other high-grade gliomas. Few cases were associated with neurofibromatosis type 1, which seems to predispose for development of APA. Although molecular genetics is still of limited value for differentiation of APA from other high-grade glioma, advanced neuroimaging techniques such as magnetic resonance perfusion imaging and spectroscopy allow improved differential work-up. In particular, APA in adults has the ability to mimic various neurological diseases such as tumefactive demyelinating lesions, low-, or high-grade gliomas. Although currently not explicitly recognized as a distinct clinico-pathologic entity it seems that adult APA behaves differently from conventional high-grade glioma and should be included in differential diagnostics to enable adequate patient care. However, further studies are needed to better understand this extremely rare disease. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  8. Amyloid pet in primary progressive aphasia: case series and systematic review of the literature.

    Science.gov (United States)

    Villarejo-Galende, Alberto; Llamas-Velasco, Sara; Gómez-Grande, Adolfo; Puertas-Martín, Verónica; Contador, Israel; Sarandeses, Pilar; González-Sánchez, Marta; Trincado, Rocío; Pilkington, Patrick; Ruiz-Solis, Sebastián; Pérez-Martínez, David A; Herrero-San Martín, Alejandro

    2017-01-01

    Primary progressive aphasia (PPA) is considered a heterogeneous syndrome, with different clinical subtypes and neuropathological causes. Novel PET biomarkers may help to predict the underlying neuropathology, but many aspects remain unclear. We studied the relationship between amyloid PET and PPA variant in a clinical series of PPA patients. A systematic review of the literature was performed. Patients with PPA were assessed over a 2-year period and classified based on language testing and the International Consensus Criteria as non-fluent/agrammatic (nfvPPA), semantic (svPPA), logopenic variant (lvPPA) or as unclassifiable (ucPPA). All patients underwent a Florbetapir (18-F) PET scan and images were analysed by two nuclear medicine physicians, using a previously validated reading method. Relevant studies published between January 2004 and January 2016 were identified by searching Medline and Web of Science databases. Twenty-four PPA patients were included (13 women, mean age 68.8, SD 8.3 years; range 54-83). Overall, 13/24 were amyloid positive: 0/2 (0%) nfvPPA, 0/4 (0%) svPPA, 10/14 (71.4%) lvPPA and 3/4 (75%) ucPPA (p = 0.028). The systematic review identified seven relevant studies, six including all PPA variants and one only lvPPA. Pooling all studies together, amyloid PET positivity was 122/224 (54.5%) for PPA, 14/52 (26.9%) for nfvPPA, 6/47 (12.8%) for svPPA, 101/119 for lvPPA (84.9%) and 12/22 (54.5%) for ucPPA. Amyloid PET may help to identify the underlying neuropathology in PPA. It could be especially useful in ucPPA, because in these cases it is more difficult to predict pathology. ucPPA is frequently associated with amyloid pathology.

  9. Strongyloides stercoralis hyperinfection syndrome: a case series and a review of the literature.

    Science.gov (United States)

    Geri, Guillaume; Rabbat, Antoine; Mayaux, Julien; Zafrani, Lara; Chalumeau-Lemoine, Ludivine; Guidet, Bertrand; Azoulay, Elie; Pène, Frédéric

    2015-12-01

    Strongyloides stercoralis may lead to overwhelming infestation [Strongyloides hyperinfection syndrome (SHS)]. We aimed at describing a case series of patients admitted in intensive care unit (ICU) with SHS and report a literature review of such cases. Retrospective multicenter study of 11 patients admitted to the ICU of tertiary hospitals with SHS between 2000 and 2013. Literature review with Pubmed retrieved 122 cases. Logistic regression analysis was performed to identify predictive factors of ICU mortality and shock occurrence. 133 patients [median age 53 (39, 64), 72.2 % males] were included. Underlying immunosuppression was present in 127 patients, mostly long-term corticosteroid treatment in 111 (83.5 %) patients. Fever (80.8 %), respiratory (88.6 %), and gastrointestinal (71.2 %) symptoms were common clinical manifestations. Shock occurred in 75 (57.3 %) patients and mechanical ventilation was required in 89 (67.9 %) patients. Hypereosinophilia and a concomitant bacterial infection were observed in 34 (34.3 %) and 51 (38.4 %) patients, respectively. The in-ICU mortality rate was 60.3 %. Predictive factors of ICU mortality were shock occurrence [Odds ratio (OR) 18.1, 95 % confidence interval (95 % CI) 3.03-107.6, p < 0.01] and mechanical ventilation (OR 28.1, 95 % CI 3.6-217, p < 0.01). Hypereosinophilia (OR 0.21, 95 % CI 0.06-0.7, p = 0.01) and a concomitant bacterial infection (OR 4.68, 95 % CI 1.3-16.8, p = 0.02) were independent predictors of shock occurrence. SHS remains associated with a poor outcome, especially when associated with shock and mechanical ventilation. Deterioration to shock is often related to concomitant bacterial infection. The poor outcome of established SHS pleads for a large application of antiparasitic primary prophylaxis in at-risk patients.

  10. [Meningioma of the olfactory groove: review of a series of 27 cases].

    Science.gov (United States)

    Lagares, A; Lobato, R D; Castro, S; Alday, R; De la Lama, A; Alén, J F; González, P

    2001-01-01

    To describe our experience with olfactory groove meningiomas, analysing their clinical and radiological form of presentation and their surgical treatment. The clinical records of 27 patients diagnosed of olfactory groove meningioma, extracted from the series of meningiomas operated on in our department since 1973, were retrospectively reviewed. Demographical data, the clinical presentation and duration of the symptoms before diagnosis were collected. Several radiological characteristics were also reviewed such as the tumour size, associated brain edema, type of contrast enhancement, presence of endostosis and invasion of the cranial base. The surgical resection grade, the histological type and the presence of recurrences in the follow-up were also analysed. The average age at presentation was 59 years. Average duration of symptoms prior to diagnosis was 39 months. The most frequent symptom at presentation was higher function impairment (52%), The average maximum tumoral diameter was 6.2 cm. 61% of the patients presented moderate or severe brain edema, which was quite frequently bilateral (74%). Radiological endostosis was present in 37% of the cases, but there were no signs of bone invasion in any case. The approach used was the basal frontal, uni or bilateral. In all cases the grade of resection was Simpson II. The majority of the cases presented a typical histology. Over 80% of the cases presented a good recovery at discharge. None of the patients presented with a tumoral recurrence after an average radiological follow-up of 74 months. The olfactory groove is an infrequent location for intracranial meningiomas, accounting for only 4.5% of all meningiomas in our experience. These tumours reach a big size due to the delay in diagnosis. Drilling of the cranial base does not seem necessary for preventing tumoral recurrence.

  11. Bipartite Atlas or Jefferson Fracture? A Case Series and Literature Review.

    Science.gov (United States)

    Allam, Emad; Zhou, Yihua

    2015-06-01

    Case series and literature review. We present a new case of a C1 anterior arch fracture after suboccipital craniotomy and C1 laminectomy to add to 3 previously reported cases, thus increasing awareness of this postoperative complication. We also present 2 adult cases of presumably congenital bipartite atlas. The radiographical similarity of these cases raises the possibility of a traumatic cause for some instances of bipartite atlas rather than a congenital defect. The bipartite atlas is a rare entity that has previously been presumed to represent a congenital variant. Its imaging appearance may be mistaken for a Jefferson fracture in the setting of trauma. The first case is a 4-year-old female who underwent suboccipital craniotomy and C1 laminectomy and was monitored over the course of the subsequent year. Two cases of bipartite atlas in young males without a history of recent trauma were observed over a similar time period and are presented for comparison. In the first case, imaging demonstrated the development of an anterior arch fracture after the C1 laminectomy surgery. Correlation of the pediatric and adult cases revealed that it may be difficult to differentiate a subacute or chronic anterior arch fracture from a congenital cleft, leading to the hypothesis that the etiology of the bipartite atlas may be traumatic rather than congenital in some cases.Review of the literature revealed that isolated anterior arch defects are extremely rare and they are more commonly seen in conjunction with posterior arch defects, which further supports our hypothesis from a biomechanical perspective. C1 laminectomy may increase the risk of an anterior C1 arch fracture. A traumatic mechanism is proposed as a cause of the bipartite atlas. In addition, the bipartite atlas may have a higher prevalence than previously reported. 4.

  12. An Empirical Evaluation of Government Scholarship Policy in Malaysia.

    Science.gov (United States)

    Mehmet, Ozay; Hoong, Yip Yat

    1985-01-01

    The effectiveness of Malaysian government scholarships, designed to achieve restructuring objectives of the New Economic Policy, was studied. A survey of 1982-1983 graduates revealed that the scholarship policy is now generating a mismatch in the high-level personnel market. In addition, distribution of scholarships benefits high-income students.…

  13. Student Learning and the Scholarship of University Teaching

    Science.gov (United States)

    Trigwell, Keith; Shale, Suzanne

    2004-01-01

    A variety of models of the scholarship of university teaching have been advocated since Boyer first proposed that the scholarship of teaching be considered as one of four forms of scholarship associated with university practices. These models have evolved from theoretical and empirically based analyses, and have as their core value concepts as…

  14. New scholarship provides opportunities for Virginia Community College graduates

    OpenAIRE

    Lazenby, Jenna

    2006-01-01

    The Office of University Scholarships and Financial Aid has launched the new"Virginia Tech-Virginia Community College System Lifeline Scholarship Program." Native Virginia Community College System (VCCS) students who complete their associates' degree are now eligible for one of six"Lifeline Scholarships," a new academic merit award given to graduates with the highest grade point average (GPA).

  15. 75 FR 9142 - Information Assurance Scholarship Program (IASP)

    Science.gov (United States)

    2010-03-01

    ... of the Secretary 32 CFR Part 240 RIN 0790-AI28 Information Assurance Scholarship Program (IASP... executing an information assurance scholarship and grant program, known as the DoD Information Assurance Scholarship Program (IASP). DATES: Comments must be received by April 30, 2010. ADDRESSES: You may submit...

  16. Faculty Scholarship at Community Colleges: Culture, Institutional Structures, and Socialization

    Science.gov (United States)

    Morest, Vanessa Smith

    2015-01-01

    This chapter looks at community college faculty engagement in scholarship. Community college faculty spend the majority of their time engaged in teaching, and therefore their scholarship typically focuses on strengthening curriculum and instruction. The paper identifies some of the structural and cultural challenges and supports to scholarship at…

  17. From Maverick to Mainstream: The Scholarship of Engagement

    Science.gov (United States)

    Driscoll, Amy; Sandmann, Lorilee R.

    2016-01-01

    A significant and growing number of universities across the country are pursuing the agenda of public and civic engagement and giving serious consideration to resultant faculty roles. Along with new university commitment come new definitions of scholarship, including the scholarship of engagement. The scholarship of engagement continues to emerge…

  18. 45 CFR 1801.50 - Acceptance of the scholarship.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Acceptance of the scholarship. 1801.50 Section 1801.50 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Payment Conditions and Procedures § 1801.50 Acceptance of the...

  19. Activities of the Professoriate: A new perspective on scholarship ...

    African Journals Online (AJOL)

    It also offers an insight into the activities that are considered scholastic and those that are not. The scholarship of teaching is an option open to the entire professoriate. The physiotherapy academicians and clinicians are challenged to embrace true scholarship. KEY WORDS: scholarship, discovery, integration, teaching, ...

  20. Left-sided and duplicate inferior vena cava: a case series and review.

    Science.gov (United States)

    Ang, Wee Choen; Doyle, Terry; Stringer, Mark D

    2013-11-01

    Left-sided and duplicate inferior vena cava (IVC) are two major anatomical variants within the spectrum of IVC malformations, both of which are developmental abnormalities of the supracardinal veins. Four clinical cases are described to highlight the computed tomographic appearances of these vascular malformations and provide novel data on venous dimensions. A systematic review of the recent literature (2000-2011) was conducted focusing on the anatomy, demographics, and associated pathology (congenital and acquired) of isolated left-sided and duplicate IVC. A total of 73 relevant articles were retrieved, consisting of case reports and small case series. The prevalence of left-sided IVC is about 0.1-0.4% and that for duplicate IVC about 0.3-0.4%; both anomalies show a slight male preponderance. In each condition, there are documented variations in the course and tributaries of the IVC. The clinical importance of these anomalies lies in three principal areas: the potential for misdiagnosis on imaging; technical difficulties during retroperitoneal surgery (particularly abdominal aortic aneurysm repair and live donor nephrectomy); and their significance in relation to the etiology and management of venous thromboembolism. Copyright © 2012 Wiley Periodicals, Inc.

  1. Statistical Analysis of fMRI Time-Series: A Critical Review of the GLM Approach

    Directory of Open Access Journals (Sweden)

    Martin M Monti

    2011-03-01

    Full Text Available Functional Magnetic Resonance Imaging (fMRI is one of the most widely used tools to study the neural underpinnings of human cognition. Standard analysis of fMRI data relies on a General Linear Model (GLM approach to separate stimulus induced signals from noise. Crucially, this approach relies on a number of assumptions about the data which, for inferences to be valid, must be met. The current paper reviews the GLM approach to analysis of fMRI time-series, focusing in particular on the degree to which such data abides by the assumptions of the GLM framework, and on the methods that have been developed to correct for any violation of those assumptions. Rather than biasing estimates of effect size, the major consequence of non-conformity to the assumptions is to introduce bias into estimates of the variance, thus affecting test statistics, power and false positive rates. Furthermore, this bias can have pervasive effects on both individual subject and group-level statistics, potentially yielding qualitatively different results across replications, especially after the thresholding procedures commonly used for inference-making.

  2. Should Prophylactic Anticoagulation Be Considered with Large Uterine Leiomyoma? A Case Series and Literature Review

    Directory of Open Access Journals (Sweden)

    Mohamed A. Satti

    2016-01-01

    Full Text Available Introduction. Uterine leiomyomas, also called uterine fibroids or myomas, are the most common pelvic tumors in women. They are very rarely the cause of acute complications. However, when complications occur they cause significant morbidity and mortality. Thromboembolic disease has been described as a rare complication of uterine leiomyomas. DVT is a serious illness, sometimes causing death due to acute PE. Cases. We report a case series of 3 patients with thromboembolic disease associated with uterine leiomyoma at Hurley Medical Center, Flint, Michigan, during 2015 and conduct a literature review on the topic. A literature search was conducted using Medline, PubMed, and PMC databases from 1966 to 2015. Conclusion. The uterine leiomyoma is a very rare cause of PE and only few cases have been reported. DVT secondary to uterine leiomyoma should be considered in a female presenting with abdominal mass and pelvic pressure, if there is no clear common cause for her symptoms. Thromboembolic disease secondary to large uterine leiomyoma should be treated with acute stabilization and then hysterectomy. Prophylactic anticoagulation would be beneficial for lowering the risk of VTE in patients with large uterine leiomyoma.

  3. Statistical Analysis of fMRI Time-Series: A Critical Review of the GLM Approach.

    Science.gov (United States)

    Monti, Martin M

    2011-01-01

    Functional magnetic resonance imaging (fMRI) is one of the most widely used tools to study the neural underpinnings of human cognition. Standard analysis of fMRI data relies on a general linear model (GLM) approach to separate stimulus induced signals from noise. Crucially, this approach relies on a number of assumptions about the data which, for inferences to be valid, must be met. The current paper reviews the GLM approach to analysis of fMRI time-series, focusing in particular on the degree to which such data abides by the assumptions of the GLM framework, and on the methods that have been developed to correct for any violation of those assumptions. Rather than biasing estimates of effect size, the major consequence of non-conformity to the assumptions is to introduce bias into estimates of the variance, thus affecting test statistics, power, and false positive rates. Furthermore, this bias can have pervasive effects on both individual subject and group-level statistics, potentially yielding qualitatively different results across replications, especially after the thresholding procedures commonly used for inference-making.

  4. HOPE Scholarships Transform the University of Georgia.

    Science.gov (United States)

    Healy, Patrick

    1997-01-01

    Georgia's merit-based HOPE scholarships, which cover tuition and fees for over half the undergraduates at the University of Georgia, are credited for bringing better students to the university but also for bringing pressure for grade inflation to the institution. Recipients must maintain a B grade average. The university has become competitive…

  5. Receive, Reorganize, Return: Theatre as Creative Scholarship

    Science.gov (United States)

    Armstrong, Sara; Braunschneider, Theresa

    2016-01-01

    This article focuses on the use of theatre as a mode of creative scholarship, from the research involved in sketch creation to the presentation of that research to academic audiences. We particularly focus on a specific sketch developed by the CRLT Players--one that explores the consequences of subtle discrimination faced by women scientists in…

  6. Defining Scholarship in Physician Assistant Education.

    Science.gov (United States)

    Opacic, Deborah A; Roessler, Elizabeth

    2017-09-01

    The goal of educational scholarship is to establish evidence that identifies excellence in teaching, curriculum design, student assessment, mentoring, advising, leadership, and administration. Our challenge as faculty is to determine what best defines this within our profession. Responsibilities of physician assistant (PA) educators include not only increasing evidence supporting quality in PA education but also outlining strategies that lead us to this success. As innovative scholars, we should focus on expanding the definition of educational scholarship by reevaluating criteria that define it. We then can explore new opportunities for faculty to develop a portfolio that endorses their academic advancement. The outcomes of this scholarship can be used to further advance PA education and clinical practice. Educational scholarship should satisfy the following: address a need, expand existing research, and be provocative, measurable, and reproducible. As innovative scholars, we should also consider analyzing existing evidence and determine whether what has been defined as best practices in the general areas of health care education are also effective in PA education. The outcomes of this research can be used to establish best practices within PA education. Cultivating a collaborative environment among programs will enable our profession to gather robust evidence supporting a quality education.

  7. NBHM MA/MSc (Mathematics) Scholarships

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 4. NBHM MA / MSc (Mathematics) Scholarships. Information and Announcements Volume 6 Issue 4 April 2001 pp 93-94. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/006/04/0093-0094 ...

  8. What's a Good Teacher? Scholarship Essential.

    Science.gov (United States)

    Conger, George R.

    1984-01-01

    Examines the characteristics of good teachers, such as belief in the dignity of students; promotion of rigorous but attainable standards; use of teaching methods suited to their personalities; and enthusiasm. Stresses good scholarship and knowledge of new research as absolute ingredients for good teachers. (LAL)

  9. In Abundance: Networked Participatory Practices as Scholarship

    Science.gov (United States)

    Stewart, Bonnie E.

    2015-01-01

    In an era of knowledge abundance, scholars have the capacity to distribute and share ideas and artifacts via digital networks, yet networked scholarship often remains unrecognized within institutional spheres of influence. Using ethnographic methods including participant observation, interviews, and document analysis, this study investigates…

  10. M. Hildred Blewett and the Blewett Scholarship

    Science.gov (United States)

    Whitten, Barbara

    2011-03-01

    M. Hildred Blewett became a physicist at a time when few women were physicists. After beginning her career at General Electric, she became a respected accelerator physicist, working at Brookhaven, Argonne, and eventually CERN. Blewett was married for a time to John Blewett, another accelerator physicist, but the couple divorced without children and she never remarried. She felt that her career in physics was hampered by her gender, and when she died in 2004 at the age of 93, she left the bulk of her estate to the American Physical Society, to found a Scholarship for women in physics. Since 2005 the Blewett Scholarship has been awarded to women in physics who are returning to physics after a career break, usually for family reasons. Family/career conflicts are one of the most important reasons why young women in early careers leave physics---a loss for them as well as the physics community, which has invested time and money in their training. The Blewett Scholarship is one way for the physics community, under the leadership of CSWP, to help these young women resume their careers. I will discuss the life and work of Hildred Blewett, the Blewett Scholarship, and its benefits to the physics community.

  11. Characteristics, scholarship and research of teacher educators

    NARCIS (Netherlands)

    Lunenberg, M.

    2010-01-01

    This article begins with a description of the diverse backgrounds and working circumstances of teacher educators and their broad scope of tasks and responsibilities. One important priority among others in the induction of novice teacher educators is enhancing scholarship and becoming

  12. Service-Based Scholarship. Special Feature.

    Science.gov (United States)

    Feingold, Ronald S.; Zlotkowski, Edward; Fiorentino, Leah Holland; Collier, Connie S.; Lawson, Hal A.; Almond, Len

    1997-01-01

    Five articles on service-based scholarship present broad issues confronting higher education, with a focus on physical education, and explore problems associated with current models. The articles note the need to move toward a more service-based model with significant connections to the community and society and present various barriers to the…

  13. Understanding the Societal Impact of Humanities Scholarship

    DEFF Research Database (Denmark)

    Pedersen, David Budtz; Johansson, Lasse Gøhler

    2016-01-01

    The critical problem for understanding the societal impact of humanities scholarship is that we currently have no satisfactory tools for understanding how wider social impacts occur and, by implication, very few guidelines for stimulating a reflexive dialogue about the influence of the humanities...

  14. Criteria for social media-based scholarship in health professions education.

    Science.gov (United States)

    Sherbino, Jonathan; Arora, Vineet M; Van Melle, Elaine; Rogers, Robert; Frank, Jason R; Holmboe, Eric S

    2015-10-01

    Social media are increasingly used in health professions education. How can innovations and research that incorporate social media applications be adjudicated as scholarship? To define the criteria for social media-based scholarship in health professions education. In 2014 the International Conference on Residency Education hosted a consensus conference of health professions educators with expertise in social media. An expert working group drafted consensus statements based on a literature review. Draft consensus statements were posted on an open interactive online platform 2 weeks prior to the conference. In-person and virtual (via Twitter) participants modified, added or deleted draft consensus statements in an iterative fashion during a facilitated 2 h session. Final consensus statements were unanimously endorsed. A review of the literature demonstrated no existing criteria for social media-based scholarship. The consensus of 52 health professions educators from 20 organisations in four countries defined four key features of social media-based scholarship. It must (1) be original; (2) advance the field of health professions education by building on theory, research or best practice; (3) be archived and disseminated; and (4) provide the health professions education community with the ability to comment on and provide feedback in a transparent fashion that informs wider discussion. Not all social media activities meet the standard of education scholarship. This paper clarifies the criteria, championing social media-based scholarship as a legitimate academic activity in health professions education. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  15. Adult-onset Alexander disease: a series of eleven unrelated cases with review of the literature.

    Science.gov (United States)

    Pareyson, Davide; Fancellu, Roberto; Mariotti, Caterina; Romano, Silvia; Salmaggi, Andrea; Carella, Francesco; Girotti, Floriano; Gattellaro, Grazietta; Carriero, Maria Rita; Farina, Laura; Ceccherini, Isabella; Savoiardo, Mario

    2008-09-01

    Alexander disease (AD) in its typical form is an infantile lethal leucodystrophy, characterized pathologically by Rosenthal fibre accumulation. Following the identification of glial fibrillary acidic protein (GFAP) gene as the causative gene, cases of adult-onset AD (AOAD) are being described with increasing frequency. AOAD has a different clinical and neuroradiological presentation with respect to early-onset AD, as abnormalities are mainly concentrated in the brainstem-spinal cord junction. We report detailed clinical and genetic data of 11 cases of AOAD, observed over a 4-year period, and a review of the previously reported 25 cases of genetically confirmed AOAD. In our series, onset occurred as late as age 62, and up to 71 in an affected deceased relative. Most cases appeared sporadic, but family history may be misleading. The most frequent symptoms were related to bulbar dysfunction-with dysarthria, dysphagia, dysphonia (seven patients)-, pyramidal involvement (seven patients) and cerebellar ataxia (seven patients). Four patients had palatal myoclonus. Sleep disorders were also observed (four cases). Bulbar symptoms, however, were infrequent at onset and two symptomatic patients had an almost pure pyramidal involvement. Two subjects were asymptomatic. Misdiagnosis at presentation was frequent and MRI was instrumental in suggesting the correct diagnosis by showing, in all cases, mild to severe atrophy of the medulla oblongata extending caudally to the cervical spinal cord. In ten patients, molecular studies revealed six novel missense mutations and three previously reported changes in GFAP. The last typical patient carried no definitely pathogenic mutation, but a missense variant (p.D157N), supposedly a rare polymorphism. Revision of the literature and the present series indicate that the clinical picture is not specific, but AOAD must be considered in patients of any age with lower brainstem signs. When present, palatal myoclonus is strongly suggestive

  16. Use of the self-controlled case-series method in vaccine safety studies: review and recommendations for best practice.

    Science.gov (United States)

    Weldeselassie, Y G; Whitaker, H J; Farrington, C P

    2011-12-01

    The self-controlled case-series method was originally developed to investigate potential associations between vaccines and adverse events, and is now commonly used for this purpose. This study reviews applications of the method to vaccine safety investigations in the period 1995-2010. In total, 40 studies were reviewed. The application of the self-controlled case-series method in these studies is critically examined, with particular reference to the definition of observation and risk periods, control of confounders, assumptions and potential biases, methodological and presentation issues, power and sample size, and software. Comparisons with other study designs undertaken in the papers reviewed are also highlighted. Some recommendations are presented, with the emphasis on promoting good practice.

  17. Making a difference: nursing scholarship and leadership in tobacco control.

    Science.gov (United States)

    Sarna, Linda; Bialous, Stella Aguinaga; Chan, Sophia S C; Hollen, Patricia; O'Connell, Kathleen A

    2013-01-01

    This report from members of the Health Behavior Expert Panel of the American Academy of Nursing (AAN) provides an overview of nurse-led scholarship in tobacco control. We reviewed published reviews of nurse-led studies in the field. The synthesis includes theory development, methodological approaches, studies focused on prevention of tobacco use, nursing interventions for tobacco dependence including studies with selected populations, investigations to reduce secondhand smoke, and studies of health care systems and policy. Gaps in the literature provided direction for stimulating nursing science, accelerating adoption of evidence-based recommendations in practice, expanding nursing education, and increasing nursing visibility and influence in health care policy efforts. The AAN is positioned to maximize nursing leadership in this effort. Copyright © 2013 Elsevier Inc. All rights reserved.

  18. Prosthetic joint infection caused by Pasteurella multocida: a case series and review of literature.

    Science.gov (United States)

    Honnorat, Estelle; Seng, Piseth; Savini, Hélène; Pinelli, Pierre-Olivier; Simon, Fabrice; Stein, Andreas

    2016-08-20

    Pasteurella multocida is a well-recognized zoonotic agent following dog or cat bites or scratches. Nevertheless, prosthetic joint infection caused by P. multocida are rarely reported. We report here a series of six cases of prosthetic joint infection caused by P. multocida managed at a referral centre for the treatment of bone and joint infection in southern France. We also reviewed the 26 cases reported in literature. The mean age of our cases was 74 years [±8.2, range 63-85]. In majority of our cases (5 cases) were associated with knee prostheses and one case with a hip prosthesis. Most of cases occurred after cat or dog scratches or licks or contact. Diagnoses of prosthetic joint infection caused by P. multocida were made by positive cultures of surgical biopsies or needle aspiration. Mean time delay between prosthetic joint implantation and infection onset was 7.6 years (±5.12 years, range 2-17). Local inflammation, which occurred in all six cases, was the most frequent clinical symptom, followed by pain in five cases, fever and swollen joints in four cases, and a fistula with purulent discharge inside the wound in two cases. The mean time of antibiotic therapy was 8 months. Surgical treatment with prosthesis removal was performed in three cases. Six of our cases were in remission without apparent relapse at 3 years after end of treatment. Prosthetic joint infections caused by P. multocida usually occur after animal scratches or bites, but can occasionally occur after a short animal lick. These infections are usually resulting from a contiguous infection and localized in the knee. An early antibiotic therapy after surgical debridement could avoid prosthetic withdrawal, notably in elderly patients. Patients with prosthetic joints should be warned that animals are potential sources of serious infection and urgent medical advice should be sought if they are bitten or scratched.

  19. Primary prevention of cardiovascular disease in patients with systemic lupus erythematosus: case series and literature review.

    Science.gov (United States)

    Fasano, S; Margiotta, D P; Navarini, L; Pierro, L; Pantano, I; Riccardi, A; Afeltra, A; Valentini, G

    2017-12-01

    Background Systemic lupus erythematosus is associated with an increased risk of cardiovascular disease. Low-dose aspirin, hydroxychloroquine and statins have been suggested to play a prophylactic role of cardiovascular events. This study is devoted to reviewing the literature on the topic and assessing the effects of these drugs in preventing a first cardiovascular event in a two-centre Italian series. Methods A PubMed search on cardiovascular prevention in systemic lupus erythematosus was performed. Moreover, systemic lupus erythematosus patients admitted to two centres from 2000-2015, who at admission had not experienced any cardiovascular event, were investigated. Aspirin, hydroxychloroquine and statin use, and the occurrence of any cardiovascular event, were recorded at each visit. Kaplan-Meier and Cox regression analyses were performed to evaluate the role of traditional, disease-related cardiovascular risk factors and of each of the three drugs in the occurrence of new cardiovascular events. Results The literature search produced conflicting results. Two hundred and ninety-one systemic lupus erythematosus patients were included in the study and followed for a median of eight years. During follow-up, 16 cardiovascular events occurred. At multivariate analysis, taking aspirin (hazard ratio: 0.24) and hydroxychloroquine for more than five years (hazard ratio: 0.27) reduced, while antiphospholipid antibody positivity (hazard ratio: 4.32) increased, the risk of a first cardiovascular event. No effect of statins emerged. Conclusion Our study confirms an additive role of aspirin and hydroxychloroquine in the primary prophylaxis of cardiovascular events in Italian patients with systemic lupus erythematosus. The lack of any detected effect in previous reports may depend on the design of studies and their short follow-up period.

  20. Health Professions Education Scholarship Unit Leaders as Institutional Entrepreneurs.

    Science.gov (United States)

    Varpio, Lara; O'Brien, Bridget; J Durning, Steven; van der Vleuten, Cees; Gruppen, Larry; Ten Cate, Olle; Humphrey-Murto, Susan; Irby, David M; Hamstra, Stanley J; Hu, Wendy

    2017-08-01

    Health professions education scholarship units (HPESUs) are organizational structures within which a group is substantively engaged in health professions education scholarship. Little research investigates the strategies employed by HPESU administrative leaders to secure and maintain HPESU success. Using institutional entrepreneurship as a theoretical lens, this study asks: Do HPESU administrative leaders act as institutional entrepreneurs (IEs)? This study recontextualizes two preexisting qualitative datasets that comprised interviews with leaders in health professions education in Canada (2011-2012) and Australia and New Zealand (2013-1014). Two researchers iteratively analyzed the data using the institutional entrepreneurship construct until consensus was achieved. A third investigator independently reviewed and contributed to the recontextualized analyses. A summary of the analyses was shared with all authors, and their feedback was incorporated into the final interpretations. HPESU leaders act as IEs in three ways. First, HPESU leaders construct arguments and position statements about how the HPESU resolves an institution's problem(s). This theorization discourse justifies the existence and support of the HPESU. Second, the leaders strategically cultivate relationships with the leader of the institution within which the HPESU sits, the leaders of large academic groups with which the HPESU partners, and the clinician educators who want careers in health professions education. Third, the leaders work to increase the local visibility of the HPESU. Practical insights into how institutional leaders interested in launching an HPESU can harness these findings are discussed.

  1. Is Medical Student Interest in Cardiothoracic Surgery Maintained After Receiving Scholarship Awards?

    Science.gov (United States)

    Trehan, Kanika; Zhou, Xun; Yang, Stephen C

    2015-09-01

    Medical student exposure to cardiothoracic surgery has been facilitated by many scholarship opportunities. This study reviews the long-term interest of students at our institution who have received such support. After the first or second year of medical school, participants were selected to receive scholarships for clinical or research activities in cardiothoracic surgery ranging from 4 to 8 weeks in duration. These were funded by the American Association for Thoracic Surgery, Society of Thoracic Surgeons, Southern Thoracic Surgical Association, or a private family donor. Over time, each student's scholarship type, current interest in cardiothoracic surgery, and current education or career status was prospectively monitored in an institutional database. Since 1999, 45 students received scholarships. Eight (18%) were funded by the American Association for Thoracic Surgery, two (4%) by The Society of Thoracic Surgeons one (2%) by the Southern Thoracic Surgical Association, and 34 (76%) by private donors. The median follow-up of graduated students is 7 years. Of the 20 (44%) with an active current interest in cardiothoracic surgery, 2 are faculty, 1 is a fellow, 1 is in an integrated 6-year program, 11 are in general surgery residency and are planning to apply to cardiothoracic surgery fellowship, and the remaining 5 are in medical school and planning a cardiothoracic surgery career. Of all former medical students who received cardiothoracic surgery research scholarships and who have now made a career choice, 17.4% chose cardiothoracic surgery. More than one-third of medical students who received scholarships in cardiothoracic surgery maintained their interest over time, and more than half maintained interest in a surgical field. Although long-term data are scarce, it remains critical to foster mentoring relationships with students over time to guide their career choices. Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights

  2. The Cultures of Contemporary Instructional Design Scholarship, Part One: Developments Based on Behavioral and Cognitive Science Foundations

    Science.gov (United States)

    Willis, Jerry

    2011-01-01

    This is the first in a series of two articles examining the current status of instructional design (ID) scholarship and theory in four different cultures or traditions. In this article, the focus is on, first, ID models based on traditional behavioral theories of learning and, second, on models based on cognitive science and the learning sciences.…

  3. Symposium on the Foundations of Newtonian Scholarship

    CERN Document Server

    Nauenberg, Michael; The foundations of Newtonian scholarship

    2000-01-01

    Newtonian scholarship has taken great steps forward in the last half-century.The recent completion of critical editions of Newton's mathematical papers and of his scientific correspondence, as well as the publication of the first volume of his optical papers and of variant readings of the Principia in the original Latin, have made most of Newton's scientific work generally available for study and analysis for the first time. This has provided a better understanding of Newton's Principia and Optics especially regarding their origin and interpretation, much of which has remained obscure for several centuries. Some of the new developments and insights are presented in this book by several of the scholars who have made these primary sources accessible, and by others who are using them to elucidate Newton's work. Most of the papers included were presented at the Symposium on the Foundations of Newtonian Scholarship, held at the Royal Society in London in March 1997.

  4. Development of Model for Providing Feasible Scholarship

    Directory of Open Access Journals (Sweden)

    Harry Dhika

    2016-05-01

    Full Text Available The current work focuses on the development of a model to determine a feasible scholarship recipient on the basis of the naiv¨e Bayes’ method using very simple and limited attributes. Those attributes are the applicants academic year, represented by their semester, academic performance, represented by their GPa, socioeconomic ability, which represented the economic capability to attend a higher education institution, and their level of social involvement. To establish and evaluate the model performance, empirical data are collected, and the data of 100 students are divided into 80 student data for the model training and the remaining of 20 student data are for the model testing. The results suggest that the model is capable to provide recommendations for the potential scholarship recipient at the level of accuracy of 95%.

  5. Late-onset neutropenia after rituximab treatment: case series and comprehensive review of the literature.

    Science.gov (United States)

    Wolach, Ofir; Bairey, Osnat; Lahav, Meir

    2010-09-01

    Rituximab is a chimeric monoclonal antibody against CD20 that is used mainly for the treatment of CD20-positive lymphoma. Recently, its use has been expanded to include treatment of other nonmalignant diseases such as rheumatologic diseases and autoimmune cytopenia. Correlating with the increased use of rituximab has been an increased number of reports of its late adverse effects. One of these is late-onset neutropenia (LON). Most investigators define LON as grade III-IV neutropenia occurring 3-4 weeks after the last treatment with rituximab, in the absence of an alternative explanation for the neutropenia.We report 6 cases of LON identified in our institution. Four patients were treated for diffuse large B-cell lymphoma, and 2 patients for follicular lymphoma. Median patient age was 68 years (range, 33-83 yr); LON appeared after a median interval of 77 days (range, 42-153 d) and lasted for a median of 5 days (range, 1-45 d). Five of the 6 patients presented with infectious complications, and 4 patients experienced recurrent episodes of neutropenia. One patient presented with LON and concomitant subacute pulmonary disease that was attributed to rituximab therapy.In addition to our own case series we present a systematic review of the literature, which we performed to compile data to describe better the syndrome of LON. Systematic studies, case series, and case reports were extracted. Most studies dealing with LON are retrospective by design and are limited by the heterogeneous populations included in the analysis. The incidence of LON is generally reported to be in the range of 3%-27%. Data regarding populations at risk are not consistent, and in some instances are conflicting.Patients considered at increased risk of LON include patients after autologous stem cell transplantation, patients treated for acquired immunodeficiency syndrome (AIDS)-related lymphoma, and patients treated with purine analogues. Patients who received previous cytotoxic treatment as well as

  6. Crimean-Congo hemorrhagic fever in pregnancy: A systematic review and case series from Russia, Kazakhstan and Turkey.

    Science.gov (United States)

    Pshenichnaya, Natalia Yurievna; Leblebicioglu, Hakan; Bozkurt, Ilkay; Sannikova, Irina Viktorovna; Abuova, Gulzhan Narkenovna; Zhuravlev, Andrey Sergeevich; Barut, Sener; Shermetova, Mutabar Bekovna; Fletcher, Tom E

    2017-05-01

    Crimean-Congo hemorrhagic fever (CCHF) is acute viral infection and a major emerging infectious diseases threat, affecting a large geographical area. There is no proven antiviral therapy and it has a case fatality rate of 4-30%. The natural history of disease and outcomes of CCHF in pregnant women is poorly understood. To systematically review the characteristics of CCHF in pregnancy, and report a case series of 8 CCHF cases in pregnant women from Russia, Kazakhstan and Turkey. A systematic review was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement protocol. PubMed, SCOPUS, Science Citation Index (SCI) were searched for reports published between January 1960 and June 2016. Two independent reviewers selected and reviewed studies and extracted data. Thirty-four cases of CCHF in pregnancy were identified, and combined with the case series data, 42 cases were analyzed. The majority of cases originated in Turkey (14), Iran (10) and Russia (6). There was a maternal mortality of 14/41(34%) and fetal/neonatal mortality of in 24/41 cases (58.5%). Hemorrhage was associated with maternal (p=0.009) and fetal/neonatal death (p<0.0001). There was nosocomial transmission to 38 cases from 6/37 index pregnant cases. Cases of CCHF in pregnancy are rare, but associated with high rates of maternal and fetal mortality, and nosocomial transmission. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  7. Health Outcomes of a Series of Bonny Method of Guided Imagery and Music Sessions: A Systematic Review.

    Science.gov (United States)

    McKinney, Cathy H; Honig, Timothy J

    2017-03-01

    The Bonny Method of Guided Imagery and Music (GIM) is a music-centered approach to exploring consciousness for personal growth and transformation. Applications have been reported in a variety of clinical and nonclinical contexts. The purpose of this study was to review evidence that a series of Bonny Method of GIM sessions may promote positive health outcomes in adults. This systematic review examined randomized and nonrandomized controlled trials and repeated measures designs that reported psychological or physiological outcomes following a series of at least six individual Bonny Method of GIM sessions. Researchers assessed each study for risk of bias and computed effect sizes for outcome variables. Of 270 non-duplicate titles retrieved, nine met criteria for inclusion, and eight had moderate or low risk of bias. These included 275 participants 18-78 years of age representing a variety of populations. Multiple studies measured anxiety, depression, mood disturbance, interpersonal problems, quality of life, sense of coherence, and/or psychiatric symptoms and found medium to large effect sizes. Four included physiological measures (systolic and diastolic blood pressure, beta-endorphin, cortisol, and pain) and reported medium to large effect sizes, none of which were replicated across studies in this review. Evidence is promising that a series of Bonny Method of GIM sessions may be effective for improving both psychological and physiological health and may be therapeutically indicated for adults seeking treatment with medical, mental health, and nonclinical needs. Further research is needed to replicate findings within outcomes and populations.

  8. VA Health Professional Scholarship and Visual Impairment and Orientation and Mobility Professional Scholarship Programs. Final rule.

    Science.gov (United States)

    2013-08-20

    The Department of Veterans Affairs (VA) is amending its VA Health Professional Scholarship Program (HPSP) regulations. VA is also establishing regulations for a new program, the Visual Impairment and Orientation and Mobility Professional Scholarship Program (VIOMPSP). These regulations comply with and implement sections 302 and 603 of the Caregivers and Veterans Omnibus Health Services Act of 2010 (the 2010 Act). Section 302 of the 2010 Act established the VIOMPSP, which authorizes VA to provide financial assistance to certain students seeking a degree in visual impairment or orientation or mobility, in order to increase the supply of qualified blind rehabilitation specialists for VA and the United States. Section 603 of the 2010 Act reauthorized and modified HPSP, a program that provides scholarships for education or training in certain health care occupations.

  9. Education of Minority Ethnic Groups in Scotland: A Review of Research. SCRE Research Report Series.

    Science.gov (United States)

    Powney, Janet; McPake, Joanna; Hall, Stuart; Lyall, Lindsay

    This review examines research done and information made available regarding the education of minority ethnic groups in Scotland. Compilers of the review used and commented on available statistical information and Scottish studies relevant to minority ethnic groups and their education at all levels. The intent of the review was to determine whether…

  10. Twenty-five years of critical care nursing scholarship in Australia.

    Science.gov (United States)

    McKinley, Sharon; Elliott, Doug

    2013-02-01

    Australian Critical Care has been published since 1988 and has been an important medium for the development of critical care nursing scholarship in Australia over 25 years. To review scholarship in critical care nursing in Australia since 1988 and record its progress in the context of developments in nursing education and intensive and critical care practice. Australian Critical Care issues since 1988 were reviewed, and abstracts from the Australian and New Zealand Annual Scientific Meeting on Intensive Care published in Australian Critical Care since the 1991 Meeting. Available evidence for the contribution of this body of scholarship to critical care nursing practice and patient care was considered. Original research reports and review articles have steadily increased from 1988 to 2012. The peak years for research publications were 2001, 2005 and 2012, and for reviews 2010 and 2011. Approximately 760 abstracts were presented at the Annual Scientific Meeting from 1991 to 2010; overall 24% were found lead to peer-reviewed publications, with an increase to 30% in recent years. Over 25 years, the scholarship of critical care nursing in Australia has evolved into an established area of disciplinary knowledge, based firmly in practice. Our discipline has witnessed the opportunity for PhD training, the introduction of professorial positions, a knowledge base built on original research and rigorous reviews, and sustainable dissemination. The challenges are to further strengthen this development, increase publication of research that is done, to demonstrate the influence on practice and to develop sustainable research funding. Copyright © 2012 Australian College of Critical Care Nurses Ltd. Published by Elsevier Ltd. All rights reserved.

  11. Coexisting genital malignancies with tuberculosis: A case series with review of literature

    Directory of Open Access Journals (Sweden)

    Avantika Gupta

    2016-01-01

    Full Text Available Objective: To study a case series of genital malignancies coexisting with genital tuberculosis. Materials and Methods: A series of three cases with known genital malignancies were found to have coexisting genital tuberculosis on subsequent workup. Results: First case was a 45 years old lady who underwent staging laparotomy for ovarian cancer. On histopathology examination, there was coexisting tuberculosis with papillary serous carcinoma. Second case was 53 years old postmenopausal lady who underwent extrafascial hysterectomy along with pelvic lymph node dissection. Histopathology showed tubercular changes along with endometrial malignancy. Third patient was a 50 years old postmenopausal lady with stage IIA carcinoma of cervix. She underwent radical hysterectomy and histopathology revealed tubercular changes in pelvic lymph nodes. All patients were given antitubercular therapy for 9 months in postoperative period along with adjuvant therapy. Conclusion: Although diagnosed as an incidental finding in the case series, genital tuberculosis may present in patients with malignancies as a result of immunosupression.

  12. 34 CFR 611.49 - What are a grantee's responsibilities for implementing the scholarship requirements before...

    Science.gov (United States)

    2010-07-01

    ... the scholarship requirements before awarding a scholarship? 611.49 Section 611.49 Education..., DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.49 What are a grantee's responsibilities for implementing the scholarship requirements before awarding a scholarship? Before awarding...

  13. 26 CFR 1.25A-3 - Hope Scholarship Credit.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Hope Scholarship Credit. 1.25A-3 Section 1.25A-3... Rates During A Taxable Year § 1.25A-3 Hope Scholarship Credit. (a) Amount of the credit—(1) In general. Subject to the phaseout of the education tax credit described in § 1.25A-1(c), the Hope Scholarship Credit...

  14. The Legacy and Future of a Model for Engaged Scholarship: Supporting a Broader Range of Scholarship

    Science.gov (United States)

    Franz, Nancy

    2016-01-01

    In this commentary, author Nancy Franz reflects on her 2009 " Journal of Higher Education Outreach and Engagement" article "A Holistic Model of Engaged Scholarship: Telling the Story across Higher Education's Missions" (EJ905411) reprinted in this 20th anniversary issue of "Journal of Higher Education Outreach and…

  15. Studying Stepfamilies: Four Eras of Family Scholarship.

    Science.gov (United States)

    Ganong, Lawrence; Coleman, Marilyn

    2017-07-23

    Historically, there have always been stepfamilies, but until the early 1970s, they remained largely unnoticed by social scientists. Research interest in stepfamilies followed shortly after divorce became the primary precursor to stepfamily formation. Because stepfamilies are structurally diverse and much more complex than nuclear families, they have created considerable challenges for both researchers and clinicians. This article examines four eras of stepfamily scholarship, tracing the development of research questions, study designs and methods, and conceptual frameworks from the mid-1970s to the present and drawing implications for the current state of the field. © 2017 Family Process Institute.

  16. Oral Granular Cell Tumor: Report of Case Series and a Brief Review of the Literature

    Directory of Open Access Journals (Sweden)

    Karakostas Panayiotis

    2017-07-01

    Full Text Available Background/Aim: The present analysis focuses on examining a case series of eight patients diagnosed with a granular cell tumor located in the oral cavity. Case series: The patients’ clinical states were thoroughly studied, along with the histopathological and immunohistochemical examinations findings. Their surgical treatment and postoperative course are also within the scope of this analysis. Numerous histogenesis theories and the appropriate tumor treatment are mentioned within the article being always in accordance with the relative literature. Conclusions: Oral granular cell tumor is a benign oral disease of possible neural origin commonly located on the tongue. Surgical excision is the treatment of choice. In any case, histological and immunohistochemical examination confirm both the clinical diagnosis and the differential diagnosis between oral squamous cell carcinoma.

  17. Serious adverse events after HPV vaccination: a critical review of randomized trials and post-marketing case series.

    Science.gov (United States)

    Martínez-Lavín, Manuel; Amezcua-Guerra, Luis

    2017-10-01

    This article critically reviews HPV vaccine serious adverse events described in pre-licensure randomized trials and in post-marketing case series. HPV vaccine randomized trials were identified in PubMed. Safety data were extracted. Post-marketing case series describing HPV immunization adverse events were reviewed. Most HPV vaccine randomized trials did not use inert placebo in the control group. Two of the largest randomized trials found significantly more severe adverse events in the tested HPV vaccine arm of the study. Compared to 2871 women receiving aluminum placebo, the group of 2881 women injected with the bivalent HPV vaccine had more deaths on follow-up (14 vs. 3, p = 0.012). Compared to 7078 girls injected with the 4-valent HPV vaccine, 7071 girls receiving the 9-valent dose had more serious systemic adverse events (3.3 vs. 2.6%, p = 0.01). For the 9-valent dose, our calculated number needed to seriously harm is 140 (95% CI, 79-653). The number needed to vaccinate is 1757 (95% CI, 131 to infinity). Practically, none of the serious adverse events occurring in any arm of both studies were judged to be vaccine-related. Pre-clinical trials, post-marketing case series, and the global drug adverse reaction database (VigiBase) describe similar post-HPV immunization symptom clusters. Two of the largest randomized HPV vaccine trials unveiled more severe adverse events in the tested HPV vaccine arm of the study. Nine-valent HPV vaccine has a worrisome number needed to vaccinate/number needed to harm quotient. Pre-clinical trials and post-marketing case series describe similar post-HPV immunization symptoms.

  18. Eosinophilic meningitis: a case series and review of literature of Angiostrongylus cantonensis and Gnathostoma spinigerum.

    Science.gov (United States)

    Shah, I; Barot, S; Madvariya, M

    2015-01-01

    Eosinophilic meningitis is defined as the presence of >10 eosinophils/μL in cerebrospinal fluid (CSF) or at least 10% eosinophils in the total CSF leukocyte count. Eosinophilic meningitis has been reported in two case series and two case reports in India till date and has not been reported in children below 15 years of age. We present two children with eosinophilic meningitis with peripheral eosinophilia and the proposed etiologic agents based on the clinical setting and their response to antihelminthic agents.

  19. Split mouth de-epithelization techniques for gingival depigmentation: A case series and review of literature

    OpenAIRE

    Kathariya, Rahul; Pradeep, A. R.

    2011-01-01

    Gingival melanin pigmentation occurs in all races of mankind. Although clinical melanin pigmentation does neither present itself as a medical problem nor a disease entity, it is a major esthetic concern for many people, especially Asians. Esthetic gingival depigmentation procedures can be performed in such patients with excellent results. This case series presents a split mouth de-epithelization procedure using popular surgical techniques such as scalpel, bur abrasion or electrosurgery. These...

  20. PS1-01: Digital Scholarship: Scientific Publishing at the Crossroads

    Science.gov (United States)

    Scobba, Virginia D

    2010-01-01

    Background/Aims: Scholarly communication is the system through which research and other scholarly writings are created, evaluated for quality, disseminated to the scholarly community, and preserved for future use. The traditional formal means of interchange, publication in peer reviewed journals, is at the core of the communication infrastructure. However, the structures and processes by which scholars communicate have undergone a major transformation in recent years with the advent of the digital age. New electronic technologies for access to information appear to be revolutionizing scholarly publishing, aptly defined by the term, digital scholarship. Current trends in the chaotic scholarly publishing market can be perceived as both opportunities for and threats to digital scholarship. Methods: Digital scholarship is in a state of unprecedented upheaval as publishers, librarians, legislators, scholarly societies, scientists and other scholars engage in tactics to propel change in directions that promote their individual goals. Strategies involve remodeling the publishing market, modifying academic and research institutional procedures, and influencing public policy. Results: Emerging digital publishing technologies, increasing volume of scholarly works, and decreasing satisfaction with a costly and dysfunctional economic model are changing the fundamental structure of scholarly publishing. Research institutions, as well as government and funding agencies, are implementing or exploring strategies which promote free and open access to research results. These include alternative copyright arrangements, e-print archives and digital repositories. Conclusion: Scholars, researchers, and society at large gain tremendous benefits from the expanded dissemination of research findings. However, several factors have impeded the progress of digital scholarship, including efforts to protect publishing revenues and profits, legal licensing restrictions, and the traditional

  1. Recommendations for the successful pursuit of scholarship by pharmacy practice faculty members.

    Science.gov (United States)

    Bosso, John A; Hastings, Jan K; Speedie, Marilyn K; Rodriguez de Bittner, Magaly

    2015-02-17

    Scholarship has long been a basic expectation of faculty members at institutions of higher learning in the United States and elsewhere. This expectation is no less assumed in academic pharmacy. A number of organizations have verbalized and enforced this precept over the years.(1-3) For example, this expectation is spoken to directly in the American Council for Pharmacy Education's Accreditation Standards and Guidelines.(4) This expectation is further emphasized in the draft document of the accreditation standards to be implemented in 2016, in Standard 20. Specifically, Element 20.2 states: "The college or school must create an environment that both requires and promotes scholarship, and must also develop mechanisms to assess both the quantity and quality of faculty scholarly productivity."(5) The successful pursuit of scholarship by clinical faculty members (those engaged in both clinical practice and teaching, without regard to tenure or clinical track status) is challenging. (6-10) Thus, faculty member job descriptions or models should be designed so clinical faculty members can successfully meet all academic job expectations, including productive and meaningful scholarship. In 2012, an AACP Section of Teachers of Pharmacy Practice task force was charged with examining this issue and providing recommendations for models for clinical faculty members that would allow the successful pursuit of scholarship. The task force gathered information relating to the current state of affairs at a number of colleges and reviewed relevant literature. This information, along with personal experiences and much discussion and contemplation, led to some general observations as well as specific recommendations. This paper reiterates the task force's observations and recommendations and provides further detail regarding our interpretation of the findings and basis for the eventual recommendations to the section.

  2. A Mentoring Program to Help Junior Faculty Members Achieve Scholarship Success

    Science.gov (United States)

    2014-01-01

    The University of North Carolina Eshelman School of Pharmacy launched the Bill and Karen Campbell Faculty Mentoring Program (CMP) in 2006 to support scholarship-intensive junior faculty members. This report describes the origin, expectations, principles, and best practices that led to the introduction of the program, reviews the operational methods chosen for its implementation, provides information about its successes, and analyzes its strengths and limitations. PMID:24672062

  3. A mentoring program to help junior faculty members achieve scholarship success.

    Science.gov (United States)

    Kohn, Harold

    2014-03-12

    The University of North Carolina Eshelman School of Pharmacy launched the Bill and Karen Campbell Faculty Mentoring Program (CMP) in 2006 to support scholarship-intensive junior faculty members. This report describes the origin, expectations, principles, and best practices that led to the introduction of the program, reviews the operational methods chosen for its implementation, provides information about its successes, and analyzes its strengths and limitations.

  4. Survey of the American College of Surgeons scholarship recipients: a story of generating academic leaders.

    Science.gov (United States)

    Upchurch, Gilbert R; Freischlag, Julie A; Novicoff, Wendy; Early, Kate; Turner, Patricia L; Zinner, Michael J

    2015-06-01

    The objective of this survey was to provide a review of the American College of Surgeons (ACS) scholarship activity. The domestic ACS scholarship recipient survey was electronically transmitted twice to awardees from 1987 to 2007 (n=253). Themes of the survey included type of practice, activities during scholarship period, success of peer review funding, and the role of mentors. All survey responses were evaluated using SPSS version 20. There were 123 total responses, with 108 separate respondents (94, 1 award; 13, 2 awards; 1, 3 awards). The group averaged 11.8 years in clinical practice, with the majority (90.2%) having an academic appointment. Seventy-seven percent of respondents were on a tenure track, and almost three-quarters (72.4%) of the respondents hold a major leadership position. In terms of research, 67.5% of respondents have received extramural funding; 10.6% have received patents. The average number of publications related to their funded research is 19.2 (range 0 to 180). Most respondents perform peer review of research (73.2%), learned about the peer review process during their funding period (82.1%), and mentor medical students (88.6%). The average number of students currently mentored is 6.4; the average total trainees mentored is 13. Despite the significant research responsibilities of respondents, they still spend more time performing clinical care (49.2%) than research (30.4%). The ACS scholarship has a significant impact on the recipient's academic career, even in the setting of increasing clinical burdens. This program also appears to tangentially identify surgeons who become leaders in academic surgery. Copyright © 2015 American College of Surgeons. Published by Elsevier Inc. All rights reserved.

  5. AHRQ series on complex intervention systematic reviews-paper 7: PRISMA-CI elaboration and explanation.

    Science.gov (United States)

    Guise, Jeanne-Marie; Butler, Mary; Chang, Christine; Viswanathan, Meera; Pigott, Terri; Tugwell, Peter

    2017-10-01

    Complex interventions are widely used in health care, public health, education, criminology, social work, business, and welfare. They have increasingly become the subject of systematic reviews and are challenging to effectively report. The Complex Interventions Methods Workgroup developed an extension to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Complex Interventions (PRISMA-CI). Following the EQUATOR Network guidance for Preferred Reporting Items for Systematic Reviews and Meta-Analysis extensions, this Explanation and Elaboration (EE) document accompanies the PRISMA-CI checklist to promote consistency in reporting of systematic reviews of complex interventions. The EE document explains the meaning and rationale for each unique PRISMA-CI checklist item and provides examples to assist systematic review authors in operationalizing PRISMA-CI guidance. The Complex Interventions Workgroup developed PRISMA-CI as an important start toward increased consistency in reporting of systematic reviews of complex interventions. Because the field is rapidly expanding, the Complex Interventions Methods Workgroup plans to re-evaluate periodically for the need to add increasing specificity and examples as the field matures. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  6. Universal in the Local: Practiscing the Scholarship of Engagement

    Directory of Open Access Journals (Sweden)

    Nancy Rottle

    2004-12-01

    Full Text Available The 'Scholarship of Engagement' is a burgeoning genre of scholarship exemplified by community-based pedagogic models used in schools of landscape architecture. This form of scholarship employs engagement with the multi-faceted particulars of local places and people, through which it can inform globally relevant principles and strategies. The paper describes attributes of the Scholarship of Engagement, which supports integrated teaching, research and service in landscape architecture and provides an example of the 'universal in the local'. It suggests that a framework for scholarship assessment developed by the Carnegie Foundation for Advancement of Teaching is effective in promoting scholarship in the design studio, incorporating the components: clear goals and problem definition; preparation through literature and research; methods including community participation, place analyses, case-study research and analysis, and solution testing through design; assessment of results; effective presentation of the results; and reflective critique by the students, community and faculty. This model frames the structure and description of community design studio work undertaken to help a small Alaskan town confront the impending influx and impacts of large chain stores, a problem communities are increasingly facing. In such an engaged-scholarship approach, the hierarchical values of cosmopolitan versus local are realigned, and faculty and students collaborate with community partners - whether global or local - to solve pressing issues. Can this integrated model of public scholarship be legitimised, supported and extended?

  7. ADE Statement of Good Practice: Teaching, Evaluation, and Scholarship.

    Science.gov (United States)

    ADE Bulletin, 2002

    2002-01-01

    Argues that scholarship, broadly defined, is essential to effective teaching and to a satisfying professional life in the humanities. Defines good teaching, and discusses ways to evaluate and encourage good teaching as well as ways to integrate teaching and scholarship. (SG)

  8. The Role of Scholarships in Study Abroad Programs

    Science.gov (United States)

    Lien, Donald

    2007-01-01

    This paper considers the role of scholarships in study abroad programs. Suppose that a university attempts to maximize the average ability of its student body by encouraging students to participate in study abroad programs. It is shown that the ideal scholarship vehicle to accomplish this is a fixed-amount award independent of a student's ability…

  9. Feminist Scholarship and the Study of Women in Higher Education.

    Science.gov (United States)

    Townsend, Barbara K.

    1992-01-01

    Presents synthesis of theories that dominate contemporary feminist scholarship. Explains four major theoretical orientations currently influencing feminist thought (liberal feminism, cultural feminism, radical feminism, and socialist feminism). Defines what is meant by feminist content and methodology in scholarship, particularly in the social…

  10. The Scholarship of Teaching and Learning in a Christian Context

    Science.gov (United States)

    Smith, David I.; Um, Joonyong; Beversluis, Claudia D.

    2014-01-01

    This article assesses the degree to which Christian scholarship has responded to the rise of the Scholarship of Teaching and Learning (SOTL). To what degree, and with what kind of disciplinary and chronological distribution, have overtly Christian publications in scholarly journals evidenced a concern with questions of teaching and learning? This…

  11. The Blind Leading the Blind: Goalball as Engaged Scholarship

    Science.gov (United States)

    Van Rheenen, Derek

    2016-01-01

    The paper describes an engaged scholarship course at a large public research university on the west coast of the United States. The pilot course introduces students to the scholarship on disability framed within the cultural studies of sport. Participants engage with existing literature while actively participating in goalball, a sport designed…

  12. Scholarship and Dental Education: New Perspectives for Clinical Faculty.

    Science.gov (United States)

    Albino, Judith E.

    1984-01-01

    Career advancement in academic dentistry appears to demand success in teaching, scholarship, and service, but foremost in research or scholarship. As a result, many dental faculty believe they are forced to choose between providing excellent professional preparation for their students or ensuring their academic careers. (MLW)

  13. Embedding the Scholarship of Engagement at a Regional University

    Science.gov (United States)

    Crookes, Patrick A.; Else, Fabienne C.; Smith, Kylie M.

    2015-01-01

    Despite receiving growing international recognition and regard, the scholarship of engagement remains undervalued internally at academic institutions, especially in relation to career development and academic promotion. This form of scholarship presents difficulties relating to evaluation, assessment, and evidencing that are not generally present…

  14. Conceptualising Transformation and Interrogating Elitism: The Bale Scholarship Programme

    Science.gov (United States)

    Botsis, Hannah; Dominguez-Whitehead, Yasmine; Liccardo, Sabrina

    2013-01-01

    In this article, we consider the extent to which a scholarship programme at the University of the Witwatersrand (Wits) engages with the challenges of transformation. This scholarship programme highlights the transformative potential of a programme that focuses on excellence for a previously under-represented group, but also demonstrates how this…

  15. A defamiliarising 'scholarship of hope': A youth subjectivity and ...

    African Journals Online (AJOL)

    ... of this article is that a scholarship of hope ought to be based on bringing understandings of excluded communities and their perspectives and knowledges to academic consciousness. Such a scholarship is also meant to inform the critical pedagogical work of educators in school classrooms and university lecture halls.

  16. Developing scholarship of teaching and learning through a ...

    African Journals Online (AJOL)

    A growing interest in the Scholarship of Teaching and Learning (SoTL) in higher education requires the seeking of opportunities for its development within and across disciplines and institutions. However, rewards for individual competitiveness in research publications, including the Scholarship of Teaching and Learning ...

  17. Community College Faculty Engagement in Boyer's Domains of Scholarship

    Science.gov (United States)

    Braxton, John M.; Lyken-Segosebe, Dawn

    2015-01-01

    This chapter describes the findings from a national survey of community college faculty. With the lens of Boyer's Domains of Scholarship applied to these findings, a more fine-grained and accurate assessment of the engagement of community college faculty members in scholarship emerges.

  18. Developing the Parameters of Scholarship in Postgraduate Coursework Studies

    Science.gov (United States)

    McLay, Allan F.

    2013-01-01

    Scholarship parameters, in relation to postgraduate coursework studies, are developed against the expectations of the Boyer classifications of scholarship (Boyer, 1990) with particular emphasis on the role of minor thesis development. An example is presented in which postgraduate coursework students are required to undertake a three semester minor…

  19. Community-Engaged Scholarship: Toward a Shared Understanding of Practice

    Science.gov (United States)

    da Cruz, Cynthia Gordon

    2018-01-01

    Community-engaged scholarship (CES) is frequently recommended as a postsecondary practice for producing knowledge to address real-world issues and support the public good. But CES has multiple meanings, and understandings overlap with similar terms, such as publicly engaged scholarship. I draw upon recommendations in the field to propose an…

  20. The Emergence of Engaged Scholarship: Seven Additional Years of Evolution

    Science.gov (United States)

    Giles, Dwight E., Jr.

    2016-01-01

    In this commentary, author Dwight Giles, Jr. reflects on his 2008 article, "Understanding an Emerging Field of Scholarship: Toward a Research Agenda for Engaged, Public Scholarship," reprinted in this 20th anniversary issue of "Journal of Higher Education Outreach and Engagement." In his original article, Giles argued that…

  1. Conceptualizing Practitioner-Scholarship for Educational Leadership Research and Practice

    Science.gov (United States)

    Lochmiller, Chad R.; Lester, Jessica Nina

    2017-01-01

    In this conceptual article, we draw upon recent literature to describe the theoretical, epistemological, and methodological anchors that can inform a working conception of practitioner-scholarship. We position practitioner-scholarship at the intersection of an individual's work as a practitioner and researcher, wherein a practitioner focuses on…

  2. Building Expertise to Support Digital Scholarship: A Global Perspective

    Science.gov (United States)

    Lewis, Vivian; Spiro, Lisa; Wang, Xuemao; Cawthorne, Jon E.

    2015-01-01

    This report sheds light on the expertise required to support a robust and sustainable digital scholarship (DS) program. It focuses first on defining and describing the key domain knowledge, skills, competencies, and mindsets at some of the world's most prominent digital scholarship programs. It then identifies the main strategies used to build…

  3. Using a writing group to promote faculty scholarship.

    Science.gov (United States)

    Houfek, Julia Fisco; Kaiser, Katherine Laux; Visovsky, Constance; Barry, Teresa L; Nelson, Audrey E; Kaiser, Margaret M; Miller, Connie L

    2010-01-01

    Writing productivity is an essential component of scholarship. Barriers to writing include intrapersonal characteristics, faculty role complexity, and time constraints. Writing groups can increase faculty members' writing, contributing to dissemination of nursing knowledge and advancement of professional nursing. The authors discuss the structure and processes of a writing group that can be adapted by faculty interested in using comentoring to increase their scholarship.

  4. The Debates in Marx's Scholarship on Dimensions of Human nature ...

    African Journals Online (AJOL)

    Debates in Marx scholarship revolve around whether Karl Marx recognizes the individual and social dimensions of human nature and which of the two he prefers. This paper considers the debates in two ways. The first relates to Marx scholarship in favour of the individual dimension of human nature. The second concerns ...

  5. African tourism scholarship: Trends in academic journal publishing ...

    African Journals Online (AJOL)

    Against the background of the growth of tourism as a sector of importance for African economies this paper reflects on an issue of growing controversy in tourism scholarship, namely the patterns of production of tourism research and of publishing in academic journals. Earlier work documented that African scholarship on ...

  6. AHRQ series on complex intervention systematic reviews-paper 3: adapting frameworks to develop protocols.

    Science.gov (United States)

    Butler, Mary; Epstein, Richard A; Totten, Annette; Whitlock, Evelyn P; Ansari, Mohammed T; Damschroder, Laura J; Balk, Ethan; Bass, Eric B; Berkman, Nancy D; Hempel, Susanne; Iyer, Suchitra; Schoelles, Karen; Guise, Jeanne-Marie

    2017-10-01

    Once a proposed topic has been identified for a systematic review and has undergone a question formulation stage, a protocol must be developed that specifies the scope and research questions in detail and outlines the methodology for conducting the systematic review. Framework modifications are often needed to accommodate increased complexity. We describe and give examples of adaptations and alternatives to traditional analytic frameworks. This article identifies and describes elements of frameworks and how they can be adapted to inform the protocol and conduct of systematic reviews of complex interventions. Modifications may be needed to adapt the population, intervention, comparators, and outcomes normally used in protocol development to successfully describe complex interventions; in some instances, alternative frameworks may be better suited. Possible approaches to analytic frameworks for complex interventions that illustrate causal and associative linkages are outlined, including time elements, which systematic reviews of complex interventions may need to address. The need for and specifics of the accommodations vary with details of a specific systematic review. This in turn helps determine whether traditional frameworks are sufficient, can be refined, or if alternate frameworks must be adopted. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  7. An evaluation of the Florence Nightingale Foundation scholarships.

    Science.gov (United States)

    Rose, Matthew; Tod, Angela; McCabe, Candy; Giordano, Richard

    2017-01-18

    The Florence Nightingale Foundation (FNF) is a charity that awards scholarships in leadership, travel and research to nurses, midwives and other healthcare professionals to promote excellence in practice. The FNF offers mentoring support to scholars, and provides support with career development and writing articles for publication, in addition to the financial award. The leadership scholarships are bespoke: leadership scholars can access a range of development opportunities that are specially commissioned for them, and select their programme of study and experiences, based on their individual needs. All scholarships provide opportunities to represent the FNF and to meet other scholars at the FNF annual conference. This article provides an overview of the FNF scholarships, based on the findings of two evaluations that demonstrated the value of these scholarships in improving services for patients and carers, as well as enhancing the careers of individual scholars.

  8. Epileptic Electroencephalography Profile Associates with Attention Defects in Children with Fragile X Syndrome: review and case series

    Directory of Open Access Journals (Sweden)

    Benjamin Cowley

    2016-07-01

    Full Text Available Fragile X syndrome (FXS is the most common cause of inherited intellectual disability and a variant of autism spectrum disorder (ASD. The FXS population is quite heterogeneous with respect to comorbidities, which implies the need for a personalized medicine approach, relying on biomarkers or endophenotypes to guide treatment. There is evidence that quantitative electroencephalography (EEG endophenotype-guided treatments can support increased clinical benefit by considering the patient’s neurophysiological profile. We describe a case series of 11 children diagnosed with FXS, aged one to 14 years, mean 4.6 years. Case data are based on longitudinal clinically-observed reports by attending physicians for comorbid symptoms including awake and asleep EEG profiles. We tabulate the comorbid EEG symptoms in this case series, and relate them to the literature on EEG endophenotypes and associated treatment options. The two most common endophenotypes in the data were diffuse slow oscillations and epileptiform EEG, which have been associated with attention and epilepsy respectively. This observation agrees with reported prevalence of comorbid behavioral symptoms for FXS. In this sample of FXS children, attention problems were found in 37% (4 of 11, and epileptic seizures in 45% (5 of 11. Attention problems were found to associate with the epilepsy endophenotype. From the synthesis of this case series and literature review, we argue that the evidence-based personalized treatment approach, exemplified by neurofeedback, could benefit FXS children by focusing on observable, specific characteristics of comorbid disease symptoms.

  9. Adenovirus urethritis and concurrent conjunctivitis: a case series and review of the literature.

    Science.gov (United States)

    Liddle, Olivia Louise; Samuel, Mannampallil Itty; Sudhanva, Malur; Ellis, Joanna; Taylor, Chris

    2015-03-01

    We present eight cases and review the literature of concurrent urethritis and conjunctivitis where adenovirus was identified as the causative pathogen. The focus of this review concerns the identification of specific sexual practices, symptoms, signs and any serotypes that seem more commonly associated with such adenovirus infections. We discuss the seasonality of adenovirus infection and provide practical advice for clinicians to give to the patient. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  10. Designing a National Longitudinal Faculty Development Curriculum Focused on Educational Scholarship: Process, Outcomes, and Lessons Learned.

    Science.gov (United States)

    Chandran, Latha; Gusic, Maryellen E; Lane, J Lindsey; Baldwin, Constance D

    2017-01-01

    Clinical educators at U.S. academic health centers are frequently disadvantaged in the academic promotion system, lacking needed faculty development, mentoring, and networking support. In 2006, we implemented the national Educational Scholars Program to offer faculty development in educational scholarship for early career educators in pediatrics. We aimed to provide them with skills, experience, and initial success in educational scholarship and dissemination. The 3-year curriculum is delivered in interactive sessions at the annual pediatric academic meetings and online intersession modules. Curriculum content progresses from educational scholarship and implementing scholarly projects to dissemination and professional networking. Intersession modules address project planning, building an educator portfolio, reviewing the literature, using technology, authorship, and peer review. Concurrently, all scholars must complete a mentored educational project and demonstrate national dissemination of a peer-reviewed product to obtain a Certificate of Excellence in Educational Scholarship. The setting of this study was a national, longitudinal, cohort-based faculty development program built within the Academic Pediatric Association, a 2,000-member professional organization. In 10 years, the Educational Scholars Program has enrolled 172 scholars in 8 cohorts; 94 have graduated so far. We describe how formative evaluation guided curriculum refinement and process improvement. Summative evaluations show that faculty and scholars were satisfied with the program. Participant outcomes from Cohort 1, assessed at Kirkpatrick's four levels of evaluation, demonstrate increases in scholarly productivity, leadership activities, and academic promotions. Curriculum building is a dynamic process of ongoing evaluation and modification. Our program benefited from designing an integrated and focused curriculum, developing educational principles to guide program improvements, creating

  11. DMPD: Translational mini-review series on Toll-like receptors: recent advances inunderstanding the role of Toll-like receptors in anti-viral immunity. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 17223961 Translational mini-review series on Toll-like receptors: recent advances i...147(2):217-26. (.png) (.svg) (.html) (.csml) Show Translational mini-review series on Toll-like receptors: r...nity. PubmedID 17223961 Title Translational mini-review series on Toll-like receptors: recent advances inund

  12. Comparing Division IA Scholarship and Non-Scholarship Student-Athletes: A Discriminant Analysis of Academic Performance

    Science.gov (United States)

    Rubin, Lisa Melanie

    2012-01-01

    Many research studies have examined the academic performance and graduation rates of college student-athletes. The limited focus on scholarship student-athletes has overlooked the majority of NCAA student-athletes, those participating in collegiate athletic programs without athletic scholarships. Therefore, this study contributes to a gap in the…

  13. Costs and Benefits of Electronic Fetal Monitoring: A Review of the Literature. NCHSR Research Report Series.

    Science.gov (United States)

    Banta, H. David; Thacker, Stephen B.

    This report focuses on electronic fetal monitoring (EFM)--a technology that was developed during the 1960s and has rapidly spread into use in clinical obstetrics. The report includes a review of the extensive published literature on EFM and related subjects. It also contains original calculations concerning the technique's specificity and…

  14. Idiopathic intracranial hypertension: lumboperitoneal shunts versus ventriculoperitoneal shunts--case series and literature review.

    LENUS (Irish Health Repository)

    Abubaker, Khalid

    2011-02-01

    Idiopathic intracranial hypertension (IIH) is an uncommon but important cause of headache that can lead to visual loss. This study was undertaken to review our experience in the treatment of IIH by neuronavigation-assisted ventriculoperitoneal (VP) shunts with programmable valves as compared to lumboperitoneal (LP) shunts.

  15. Review of the Series "Disease of the Year 2011: Toxoplasmosis" Pathophysiology of Toxoplasmosis

    NARCIS (Netherlands)

    Subauste, C.S.; Ajzenberg, D.; Kijlstra, A.

    2011-01-01

    Toxoplasma gondii is a major cause of chronic parasitic infection in the world. This protozoan can cause retino-choroiditis in newborns and in adults, both immunocompetent and immunodeficient. This disease tends to be recurrent and can lead to severe visual impairment. The authors review current

  16. Concepts and design of chemical reactors. Volume 3 in the chemical engineering: Concepts and reviews series

    Energy Technology Data Exchange (ETDEWEB)

    Whitaker, S.; Cassano, A.E.

    1986-01-01

    This work provides researchers and practitioners with information regarding concepts in chemical reactor design. The text presents the fundamentals of multiphase transport phenomena with heterogeneous reactions and the efficient computational determination of effectiveness factors. The most recent developments, applications, and current design strategies for each of the classic types of chemical reactors: fixed bed, fluidized bed, slurry, trickle bed, and photoreactors are reviewed.

  17. Leadership Development Book Review Series: "The Female Advantage: Women's Ways of Leadership."

    Science.gov (United States)

    Cradick, Denise

    1992-01-01

    Sally Helgesen's book, "The Female Advantage: Women's Ways of Leadership," is reviewed. The book was based on a survey of women concerning leadership and addresses gender differences in management and leadership styles; management as a circular process; group communication; and leader roles. (MSE)

  18. Implant-associated Vertical Root Fracture in Adjacent Endodontically Treated Teeth: A Case Series and Systematic Review.

    Science.gov (United States)

    Rosen, Eyal; Beitlitum, Ilan; Tamse, Aviad; Taschieri, Silvio; Tsesis, Igor

    2016-06-01

    This study aimed to report a possible effect of the presence of an adjacent implant on the development of a vertical root fracture (VRF) in endodontically treated teeth. A series of 8 cases in 7 patients with teeth diagnosed with VRF after the placement of implants in the adjacent area is described and analyzed. In addition, a comprehensive literature search with strict inclusion and exclusion criteria was undertaken to identify additional clinical studies that assessed this clinical scenario. The case series analysis revealed that the time from implant placement to the diagnosis of VRF was between 5 and 28 months (average = 11 months). The majority of cases occurred in female patients who received 2 or more implants. Six of the 7 patients were older than 40 years, with an average age of 54 years. The majority of teeth with VRF were premolar or mandibular molar teeth (6/8 teeth). All fractured teeth had been restored with a crown and had a post present, and the quality of the root canal filling was determined to be adequate. The systematic review revealed that implant-associated VRF has not been investigated or reported in the literature yet. Based on a systematic review of the literature, this case series, although limited in its extent, is the first clinical report of a possible serious adverse event of implant-associated VRF in adjacent endodontically treated teeth. Additional clinical studies are indicated to shed light on this potential phenomenon. Copyright © 2016 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  19. Management of blunt tracheal trauma in children: a case series and review of the literature.

    Science.gov (United States)

    Duval, Elisabeth L; Geraerts, Saskia D; Brackel, Hein J

    2007-06-01

    Blunt tracheal trauma seldom develops in children because of their anatomy and the mobility of the cartilage. It has the potential to be overlooked, either because of the severity of concomitant injuries or because of the unfamiliarity of paediatricians with this type of injury. However, tracheal injury might be lethal due to airway compromise. Early bronchoscopy may be necessary to anticipate complications and prevent permanent dysfunction. We present a retrospective, double-institution case series over a 5-year period, describing five children, aged 3 to 14 years, with tracheal injury after blunt cervical trauma. All patients showed emphysema with pneumomediastinum. After explorative bronchoscopy, all patients were successfully treated with antibiotics and/or supportive ventilation. In summary, minimal lesions due to blunt tracheal trauma could be treated conservatively in children. Since the external signs of tracheal injury are not indicative of the extent of the trauma, a high index of suspicion is warranted in these patients.

  20. NUT midline carcinoma of the larynx: an international series and review of the literature.

    Science.gov (United States)

    Hellquist, Henrik; French, Christopher A; Bishop, Justin A; Coca-Pelaz, Andrés; Propst, Evan J; Paiva Correia, António; Ngan, Bo-Yee; Grant, Ronald; Cipriani, Nicole A; Vokes, David; Henrique, Rui; Pardal, Fernando; Vizcaino, Jose Ramon; Rinaldo, Alessandra; Ferlito, Alfio

    2017-05-01

    NUT midline carcinoma (NMC) is a rare undifferentiated and aggressive carcinoma that locates characteristically to the midline of the head and neck, and mediastinum. NMC is characterized by chromosomal rearrangements of the gene NUT, at 15q14. The BRD4 gene on 19q13 is the most common translocation partner forming a fusion oncogene, BRD4-NUT. By the end of 2014, the International NUT Midline Carcinoma Registry had 48 patients treated for NMC. Laryngeal NMC are exceedingly rare, and we report a case series of seven cases. We searched for cases in files of different hospitals as well as a thorough search of the English language literature. The diagnosis of NMC is made by demonstration of NUT rearrangement either by immunohistochemistry, fluorescence in-situ hybridization (FISH) or reverse transcription-polymerase chain reaction (RT-PCR). We found three previously published cases, and in this series add four cases of our own. NMC consists of monomorphic, often discohesive, cells with an epithelioid appearance and distinct nucleoli. The tumours typically show abrupt squamous differentiation. The mean age of the patients was 34 years, hence significantly lower than that for conventional laryngeal carcinoma. All tumours were located in the supraglottis and five patients died of the disease after 3, 7, 8, 9 and 11 months. Laryngeal NMC may be underdiagnosed, and an increased awareness among pathologists is warranted. NMC has characteristic morphological features, and positive immunostaining with the NUT antibody is diagnostic. Its aggressive behaviour demands a very intense treatment strategy and the need for its recognition is emphasized further by new promising treatment strategies. © 2016 John Wiley & Sons Ltd.

  1. The ripple effect: personal scholarships and impact on practice development

    Directory of Open Access Journals (Sweden)

    Lesley Baillie

    2015-05-01

    Full Text Available Background: Practice development projects are often situated within a specific context and team, while scholarship awards focus more on the personal and professional development of individuals. Personal and professional development is an important component of practice development, however, and this paper reports on a survey of nurses and midwives who had been awarded personal scholarships and examines the scholars’ perceptions of the impact on practice development. Few studies of scholarships and their impact have been published previously. Aims: 1. To present the outcomes of a research project that evaluated scholarships awarded to nurses and midwives, within the context of practice development 2. To critique the role of personal scholarships as a means to support practice development and/ or service improvement Methods: An online cross-sectional survey of nurses and midwives who had been awarded scholarships by a UK charity was conducted; 82 scholars responded, a 59% response rate. Quantitative data were analysed using descriptive statistics and free text comments were analysed thematically. Results: Scholars overwhelmingly perceived a positive impact on their personal and professional development but most also believed there had been a positive impact on patient care, safety and experience, and on colleagues and their organisation; some referred to the latter as a ‘ripple’ effect of their scholarship. An analysis of these results indicated some synergy with practice development values. Conclusions: The award of scholarships to individuals appears to have a wider impact on scholars’ colleagues and their organisation with a resulting impact on practice development. This is important as few individuals are awarded personal scholarships. The explicit promotion of personal scholarships within a practice development framework could further develop the relationship between the two, affirming a wider impact of the awards. The sustainability

  2. Mesiotemporal Disconnection and Hypoactivity in Klüver-Bucy Syndrome: Case Series and Literature Review.

    Science.gov (United States)

    Caro, Mario A; Jimenez, Xavier F

    2016-08-01

    Klüver-Bucy syndrome (KBS) is often perceived as rare and limited to cases with bilateral amygdala destruction. In fact, various alternate mechanisms may be involved, warranting exploration of the syndrome's presentation, pathophysiology, prognosis, and management. Clinical management and the electronic medical records were examined for 2 patients diagnosed with partial KBS (ICD-10 F07.0) after experiencing ≥ 3 of the following: placidity, indiscriminate dietary behavior, hyperorality, hypersexuality, visual agnosia, and hypermetamorphosis. A literature search was performed in April 2015 by using the keyword Kluver-Bucy in PubMed and Ovid databases for English language publications since inception. Additionally, the authors reviewed the reference list of these publications in order to identify additional reports. Studies were included if they had information about presentation, pathophysiology, syndrome treatment or management, and course of KBS. Information about our KBS cases was obtained by reviewing electronic medical records and by direct observation of the patients. A total of 186 (PubMed) and 137 (Ovid) publications were identified in each database. We ultimately reviewed 109 articles containing information about KBS, finding 51 publications addressing relevant aspects of this syndrome. The first case demonstrates KBS secondary to mesiotemporal structural atrophy, and the second illustrates transient KBS due to functional, postictal, hypoactivity within such structures. Literature review and discussion regarding both prognosis and treatment of KBS follows. Klüver-Bucy syndrome may be underreported due to a limited understanding of the syndrome as one necessitating bilateral amygdaloid destruction. The syndrome can be seen with damage/hypofunction of the hippocampal-amygdaloid complex and its projections. The prognosis of KBS is variable, and its treatment is based on a combination of environmental and pharmacologic measures. © Copyright 2016 Physicians

  3. Anesthetic and Obstetric Management of Syringomyelia During Labor and Delivery: A Case Series and Systematic Review.

    Science.gov (United States)

    Garvey, Gráinne Patricia; Wasade, Vibhangini S; Murphy, Kellie E; Balki, Mrinalini

    2017-09-01

    Syringomyelia is a rare, slowly progressive neurological condition characterized by the presence of a syrinx within the spinal cord. Consensus regarding the safest mode of delivery and anesthetic management in patients with syringomyelia remains controversial and presents management dilemmas. This study reviews the cases of syringomyelia at our institution and provides a systematic review of the literature to guide decisions regarding labor and delivery management. A retrospective review of cases at our hospital from 2002 to 2014 and a systematic review of the literature from 1946 to 2014 were undertaken. Hospital records and electronic databases were interrogated using International Classification of Diseases, 10th Revision codes and the keywords "syringomyelia," "syringobulbia," and "pregnancy." Data regarding demographics, diagnosis, radiology reports, neurological symptoms, mode of delivery, anesthetic management, and maternal-fetal outcomes were collected. We collected and analyzed data on a total of 43 pregnancies in 39 patients. The most common location for syrinx was in the cervicothoracic region (41.9%). The large majority of patients (n = 34; 87%) demonstrated signs and symptoms associated with syringomyelia before delivery. Syringomyelia associated with Arnold Chiari malformation was documented in 49% (n = 21) cases. General anesthesia was the most commonly used (n = 21/30, 70%) anesthetic technique for cesarean delivery. The majority (n = 9/13, 69%) of patients had an epidural sited for labor analgesia. There were no maternal or neonatal complications associated with neuraxial anesthesia; however, 3 cases (14%) raised concerns regarding general anesthesia including difficult intubation, transient worsening of neurological symptoms postpartum, and prolonged muscle paralysis after atracurium. Despite concerns regarding aggravation of the syrinx with vaginal delivery, this mode of delivery has never caused any documented long-term worsening of neurological

  4. Congenital Treves' field transmesenteric hernia in children: A case series and literature review

    Directory of Open Access Journals (Sweden)

    Ryuta Saka

    2015-08-01

    Full Text Available Transmesenteric hernia is abdominal visceral herniation through a congenital or acquired mesenteric defect. Treves' field is the area of terminal ileal mesentery circumscribed by the ileocolic artery and its last ileal branch. It is very susceptible to congenital defects. To clarify the clinical course of congenital Treves' field transmesenteric hernia (cTFTH, we retrospectively reviewed pediatric cases and conducted a literature review. Five consecutive pediatric cTFTH cases (one male, four females underwent emergency laparotomy at our institutions from April 2009 and December 2014. We analyzed their demographics, preoperative findings, surgical procedures, and outcomes, along with a literature review. Abdominal plain X-ray showed displaced intestinal gas with gas paucity in the center of the abdomen in two cases and diffusely increased intestinal gas in two others. Abdominal computed tomography (CT in four cases showed intestinal loop clusters, mesenteric vessel changes, small-bowel obstruction, and ascites. All cases underwent emergency laparotomy for ileal resection with ileocecal valve preservation. Simultaneous anastomoses were performed in four cases; the remaining case underwent ileostomy because of prematurity. Although one case needed reoperation for postoperative bowel obstruction, all patients survived. Literature review of pediatric cTFTH showed a high frequency of necrosis (70.5% and mortality (26.5%. Among pediatric cTFTH cases, 67.6% were aged <5 years. Mesenteric defect was <5 cm in 70% cases. We should be aware of the clinical importance and radiological features of pediatric cTFTH. Abdominal CT may provide useful information.

  5. Surgical excision of symptomatic sacral perineurial Tarlov cyst: case series and review of the literature.

    Science.gov (United States)

    Elsawaf, Ahmed; Awad, Tariq Elamam; Fesal, Salem S

    2016-11-01

    Symptomatic sacral perineural cysts are extremely rare. The aim of this retrospective study is to investigate the outcome of 15 consecutive patients treated by microsurgical resection of the cyst and to review the literature. The authors retrospectively reviewed their clinical data archive from 2002 to 2014. Fifteen patients who were operated on due to symptomatic sacral perineural cysts were enrolled in the study. Patients' symptoms, radiographs, intra-operative findings, and clinical results were evaluated. All 15 patients underwent microsurgical excision of the cyst. The literature on this topic available in PubMed was also reviewed. There were 5 men and 10 women included in the study, with a mean age of 31 years (range 7-60 years). Preoperative symptoms include low back pain, coccydynia, buttock pain, perianal pain and radicular pain. All of the patients underwent surgical resection. The mean follow-up was 54 months (range 3-160 months). All the patients experienced complete or substantial resolution of the preoperative local and radicular pain after surgery. Cyst excision is an effective and safe technique for symptomatic sacral perineural (Tarlov) cysts. Careful patient selection is vital to the management and treatment of this difficult and controversial pathology.

  6. "All Our Relations": Respecting People and Scholarship

    DEFF Research Database (Denmark)

    Lysgaard, Jonas Greve; Neilson, Alison; Spannring, Reingaard

    simple and complex, drew us to seek a circle of renewal and remembering of life and lives that may have been forgotten at times within ESER.The phrase “all our/my relations” comes from indigenous worldviews and practices of honouring all the people who have come before you as well as the other living...... with complex histories and inequities (Glass, Scott & Price, 2012; Sund & Öhman, 2014). We will respect people and scholarship via three main currents of discussion:The role of love in ESER“Ignored concepts” - Research and extensive discourse that gets ignored when defining questions that assume people...... are selfish and have never cooperated to protect the commons, or are not politically active (Gaiser, Rijke & Spanning, 2010) uncritical acceptance of people/nature dichotomy, uncritical use of education as transferring information from expert to ignorant.Political dimensions of ESER (postcolonial lens, global...

  7. Infection after vertebroplasty or kyphoplasty. A series of nine cases and review of literature.

    Science.gov (United States)

    Abdelrahman, Hamdan; Siam, Ahmed Ezzat; Shawky, Ahmed; Ezzati, Ali; Boehm, Heinrich

    2013-12-01

    Percutaneous augmentation with bone cement is a widely accepted modality of treatment for thoracic and lumbar vertebral osteoporotic fractures. Infection after vertebroplasty or kyphoplasty is a serious, yet, rarely reported complication. To present a case series with a long-term follow-up of spinal infection after vertebroplasty/kyphoplasty with analysis of preoperative condition, risk factors, diagnostic findings, time before reoperation, causative organism, treatment, and outcome. A retrospective, uncontrolled clinical case series in a single institution. Between January 1997 and June 2012, 1,307 patients underwent percutaneous vertebroplasty or kyphoplasty. Six cases had postoperative infection (0.46%) and three additional cases were referred from other institutions for salvage treatment. Perioperative assessment included visual analog scale, clinical, laboratory, and imaging findings, and activities of daily living at the end of the follow-up. Nine patients were included: six females and three males (mean age 73.8 years). Comorbidities were found in all patients. Kyphoplasty had been done in five patients and vertebroplasty in four. The interval between augmentation and revision surgery ranged from 10 to 395 days with a mean of 118.4 days. Three cases with early infection presented within 1 month. Infection parameters were high in all patients at readmission. All patients were treated surgically except one case who died before the planned revision surgery. In all cases, debridement and corpectomy were done through anterior approaches combined with posterior instrumentation. The most common causative organism was Staphylococcus aureus in three cases. Mean follow-up period after the revision surgery was 26.68 months, excluding two patients who died early in the follow-up (within 4 months). This amounts to a mortality rate of 33.3% perioperatively. At the end of follow-up, two patients had unrestricted activities and one patient required a walker. Of three

  8. Problems in Translating Figures of Speech: A Review of Persian Translations of Harry Potter Series

    Directory of Open Access Journals (Sweden)

    Fatemeh Masroor

    2016-12-01

    Full Text Available Due to the important role of figures of speech in prose, the present research tried to investigate the figures of speech in the novel, Harry Potter Series, and their Persian translations. The main goal of this research was to investigate the translators’ problems in translating figures of speech from English into Persian. To achieve this goal, the collected data were analyzed and compared with their Persian equivalents. Then, the theories of Newmark (1988 & 2001, Larson (1998, and Nolan (2005 were used in order to find the applied strategies for rendering the figures of speech by the translators. After identifying the applied translation strategies, the descriptive and inferential analyses were applied to answer the research question and test its related hypothesis. The results confirmed that the most common pitfalls in translating figures of speech from English into Persian based on Nolan (2005 were, not identifying of figures of speech, their related meanings and translating them literally. Overall, the research findings rejected the null hypothesis. The findings of present research can be useful for translators, especially beginners. They can be aware of the existing problems in translating figures of speech, so they can avoid committing the same mistakes in their works.

  9. Presigmoid Approach to Vertebrobasilar Artery Aneurysms: A Series of 31 Patients and Review of the Literature.

    Science.gov (United States)

    Tjahjadi, Mardjono; Niemelä, Mika; Kivelev, Juri; Serrone, Joseph; Maekawa, Hidetsugu; Jahromi, Behnam Rezai; Kerro, Oleg; Hafez, Ahmad; Lehto, Hanna; Kivisaari, Riku; Hernesniemi, Juha

    2016-08-01

    The presigmoid approach can be used to treat vertebrobasilar artery aneurysms when circumstances require more operative exposure. High morbidity and mortality in these cases have been reported. In this study, we describe our modified presigmoid approach for vertebrobasilar artery aneurysms and our clinical results. This series includes patients with vertebrobasilar aneurysms clipped via the modified presigmoid approach at the Department of Neurosurgery at Helsinki University Hospital from 1998 to 2014. Data were collected from the operating record books, patients' medical records, and a radiologic database server. Thirty-three presigmoid procedures of 31 patients were performed to treat 34 aneurysms (14 ruptured, 20 unruptured). The aneurysms had a mean distance from the posterior clinoid process to the aneurysm neck of 12.2 mm (range, 0-26.6 mm). A favorable outcome was achieved in 21 patients (64%). A favorable outcome was achieved in 74% of unruptured and good-grade patients, whereas favorable outcome was achieved in only 36% of poor-grade patients. Complete or near-complete occlusion was achieved in 79%. Larger aneurysms, fusiform morphology, and anterior dome projection had lower occlusion rates. We have described our experiences of using the presigmoid approach to treat vertebrobasilar aneurysms. The clinical and radiographic results are acceptable given the complex location and configuration of the treated aneurysms. Unfavorable outcomes are related to the poor admission Hunt and Hess grade, aneurysm morphology, and aneurysm size. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Modern management of pyogenic hepatic abscess: a case series and review of the literature.

    LENUS (Irish Health Repository)

    Heneghan, Helen M

    2012-01-31

    BACKGROUND: Pyogenic hepatic abscesses are relatively rare, though untreated are uniformly fatal. A recent paradigm shift in the management of liver abscesses, facilitated by advances in diagnostic and interventional radiology, has decreased mortality rates. The aim of this study was to review our experience in managing pyogenic liver abscess, review the literature in this field, and propose guidelines to aid in the current management of this complex disease. METHODS: Demographic and clinical details of all patients admitted to a single institution with liver abscess over a 5 year period were reviewed. Clinical presentation, aetiology, diagnostic work-up, treatment, morbidity and mortality data were collated. RESULTS: Over a 5 year period 11 patients presented to a single institution with pyogenic hepatic abscess (55% males, mean age 60.3 years). Common clinical features at presentation were non-specific constitutional symptoms and signs. Aetiology was predominantly gallstones (45%) or diverticular disease (27%). In addition to empiric antimicrobial therapy, all patients underwent radiologically guided percutaneous drainage of the liver abscess at diagnosis and only 2 patients required surgical intervention, including one 16-year old female who underwent hemi-hepatectomy for a complex and rare Actinomycotic abscess. There were no mortalities after minimum follow-up of one year. CONCLUSIONS: Pyogenic liver abscesses are uncommon, and mortality has decreased over the last two decades. Antimicrobial therapy and radiological intervention form the mainstay of modern treatment. Surgical intervention should be considered for patients with large, complex, septated or multiple abscesses, underlying disease or in whom percutaneous drainage has failed.

  11. Modern management of pyogenic hepatic abscess: a case series and review of the literature

    Directory of Open Access Journals (Sweden)

    Ryan Ronan S

    2011-03-01

    Full Text Available Abstract Background Pyogenic hepatic abscesses are relatively rare, though untreated are uniformly fatal. A recent paradigm shift in the management of liver abscesses, facilitated by advances in diagnostic and interventional radiology, has decreased mortality rates. The aim of this study was to review our experience in managing pyogenic liver abscess, review the literature in this field, and propose guidelines to aid in the current management of this complex disease. Methods Demographic and clinical details of all patients admitted to a single institution with liver abscess over a 5 year period were reviewed. Clinical presentation, aetiology, diagnostic work-up, treatment, morbidity and mortality data were collated. Results Over a 5 year period 11 patients presented to a single institution with pyogenic hepatic abscess (55% males, mean age 60.3 years. Common clinical features at presentation were non-specific constitutional symptoms and signs. Aetiology was predominantly gallstones (45% or diverticular disease (27%. In addition to empiric antimicrobial therapy, all patients underwent radiologically guided percutaneous drainage of the liver abscess at diagnosis and only 2 patients required surgical intervention, including one 16-year old female who underwent hemi-hepatectomy for a complex and rare Actinomycotic abscess. There were no mortalities after minimum follow-up of one year. Conclusions Pyogenic liver abscesses are uncommon, and mortality has decreased over the last two decades. Antimicrobial therapy and radiological intervention form the mainstay of modern treatment. Surgical intervention should be considered for patients with large, complex, septated or multiple abscesses, underlying disease or in whom percutaneous drainage has failed.

  12. Benzene-contaminated toluene and acute myeloid leukemia: a case series and review of literature.

    Science.gov (United States)

    Peckham, Trevor; Kopstein, Melvyn; Klein, Jason; Dahlgren, James

    2014-02-01

    We report seven cases of acute myeloid leukemia (AML) with occupational exposure to a toluene-based hydrocarbon solvent. The cases were employed at a facility, which manufactured rubber belts and hoses, between 1950 and 2005 for periods ranging from 21 to 37 total years. Detailed histories were obtained for three workers who were diagnosed with AML within a 3-year period (2003-2005). Death certificates, medical records, and accounts by workers were reviewed. Benzene, a known cause of AML, is typically a contaminant of toluene. Benzene contamination in toluene and other widely used solvents and the potential for concurrent benzene exposure during usage of these solvents in occupational settings are discussed.

  13. Drug induced erythema multiforme: two case series with review of literature.

    Science.gov (United States)

    Shah, Shreyas N; Chauhan, Girish R; Manjunatha, B S; Dagrus, Kapil

    2014-09-01

    Erythema Multiforme, (EM) an uncommon, acute inflammatory reactive mucocutaneous disorder and primary allergies confined to the oral mucosa. However the subsequent attacks can produce more severe forms of EM involving the skin. Manifestations of EM are varied and present a diagnostic dilemma because infections (particularly herpes simplex and mycoplasma pneumoniae) and drugs seem to predispose towards development of EM. We report two cases of EM in which drugs (Dioclofenac sodium & Amoxycilline) seems to be precipitating factor. In addition, the article reviews various aspects of EM as relevant to dental practice and highlight the associated potential etiologic agents, pathogenic mechanisms and therapies.

  14. Idiopathic intracranial hypertension: lumboperitoneal shunts versus ventriculoperitoneal shunts--case series and literature review.

    LENUS (Irish Health Repository)

    Abubaker, Khalid

    2012-02-01

    OBJECTIVES: Idiopathic intracranial hypertension (IIH) is an uncommon but important cause of headache that can lead to visual loss. This study was undertaken to review our experience in the treatment of IIH by neuronavigation-assisted ventriculoperitoneal (VP) shunts with programmable valves as compared to lumboperitoneal (LP) shunts. METHODS: A retrospective chart review was conducted on 25 patients treated for IIH between 2001 and 2009. Age, sex, clinical presentation, methods of treatment and failure rates were recorded. RESULTS: Seventy-two per cent were treated initially with LP shunts. Failure rate was 11% in this group. Neuronavigation-assisted VP shunts were used to treat 28%. In this group, the failure rate was 14%. CONCLUSION: Our experience indicates that both LP shunts and VP shuts are effective in controlling all the clinical manifestations of IIH in the immediate postoperative period. Failure rates are slightly higher for VP shunts (14%) than LP shunts (11%). However, revision rates are higher with LP shunts (60%) than with VP shunts (30%).

  15. Ischemic bandage injuries: a case series and review of the literature.

    Science.gov (United States)

    Anderson, D M; White, R A

    2000-01-01

    To determine the prognosis and distribution of ischemic injuries caused by inappropriate bandaging of the lower limb in dogs and cats. Retrospective clinical study. Eleven client-owned animals, including 9 dogs and 2 cats with a history of injuries consistent with incorrect application of a bandage. Medical records for dogs and cats referred to the Queen's Veterinary School Hospital with limb wounds between 1995 and 1999 were reviewed for clinical history and referring veterinary surgeons' reports, indicating that the injury was directly related to the application of a bandage to the limb. The indications for bandage application included 2 postoperative cruciate ligament ruptures, 2 lacerations, 3 internal fixations, an onychectomy, a shoulder dislocation, a dog bite, and a tendon strain. None of the patients had other body systems involved or underlying or concurrent diseases. Five different types of bandage were described (support, Robert Jones, pressure, splint, and Velpeau), and no particular age or breed was overrepresented. Of the 11 animals, 5 required full-thickness skin grafts, 3 had to have digits amputated, and 2 required limb amputations. Nine animals survived, but only 4 became fully functional on the affected limb. Bandage-related injuries are potentially serious sequelae to a routine procedure. A guarded prognosis should be given when there is loss of deeper structures. A review of bandaging principles is presented. Method of application, choice of materials, and close monitoring of the bandage are important factors in preventing iatrogenic injury.

  16. Immunoresponsive Autonomic Neuropathy in Sjögren Syndrome-Case Series and Literature Review.

    Science.gov (United States)

    Goodman, Brent P

    2017-03-31

    Sjögren syndrome (SS) is one of the most common autoimmune disorders that classically affects exocrine glands, resulting in keratoconjunctivitis sicca and xerostomia, and frequently is associated with other systemic symptoms. SS appears to have a particular predilection for involving the autonomic nervous system. Does immunotherapy improve signs and symptoms of autonomic nervous system impairment in SS? This is a retrospective review of patients seen in the autonomic clinic at our institution who underwent an evaluation for a suspected autonomic disorder that ultimately was attributed to SS. SS patients who were treated with immunotherapy and completed autonomic testing before and after treatment were included in this review. A total of 4 patients were identified who were treated for SS-related autonomic dysfunction with immunotherapy and underwent repeat autonomic testing after treatment. Marked clinical and functional improvement was seen after treatment with intravenous immunoglobulin in all patients and adjunctive rituximab therapy in 1 patient. The clinical improvement with immunotherapy in these patients correlated with markedly improved findings on autonomic testing in all. Clinical symptoms and results of autonomic testing prior to and following immunotherapy were assessed. Autonomic signs and symptoms in SS are potentially immunoresponsive, but immunotherapy in these patients may require repeated, ongoing, or adjunctive therapy for optimal and sustained improvement.

  17. SLE and Non-Hodgkin's Lymphoma: A Case Series and Review of the Literature.

    Science.gov (United States)

    Boddu, Prajwal; Mohammed, Abdul S; Annem, Chandrahasa; Sequeira, Winston

    2017-01-01

    Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder punctuated by varied multiorgan complications all along the course of its natural history. Lymphoma represents a relatively well-recognized malignant phenomenon associated with lupus. The cause and effect relationships of lymphoma in SLE have been subject to extensive scrutiny with several studies reporting on clinic-pathologic characteristics and risk factors predicting lymphoma development in SLE. However, the pathogenic role of immunosuppressives in SLE-related lymphoma still remains unclear, and indices to help guide diagnosis, prognostication, therapy, and posttreatment monitoring are yet to be established. In this review, we describe 3 SLE patients who developed non-Hodgkin's lymphoma at different time points of their disease. Through a careful dissection of the aforementioned cases, we intend to apprise readers of the currently available literature surrounding risk factors, management, and prognosis in SLE-related lymphoma. We will also review and discuss the implications of immunosuppressives in SLE-related lymphoma and the role of mycophenolate mofetil in SLE-related primary CNS lymphoma development.

  18. SLE and Non-Hodgkin’s Lymphoma: A Case Series and Review of the Literature

    Directory of Open Access Journals (Sweden)

    Prajwal Boddu

    2017-01-01

    Full Text Available Systemic lupus erythematosus (SLE is a multisystem autoimmune disorder punctuated by varied multiorgan complications all along the course of its natural history. Lymphoma represents a relatively well-recognized malignant phenomenon associated with lupus. The cause and effect relationships of lymphoma in SLE have been subject to extensive scrutiny with several studies reporting on clinic-pathologic characteristics and risk factors predicting lymphoma development in SLE. However, the pathogenic role of immunosuppressives in SLE-related lymphoma still remains unclear, and indices to help guide diagnosis, prognostication, therapy, and posttreatment monitoring are yet to be established. In this review, we describe 3 SLE patients who developed non-Hodgkin’s lymphoma at different time points of their disease. Through a careful dissection of the aforementioned cases, we intend to apprise readers of the currently available literature surrounding risk factors, management, and prognosis in SLE-related lymphoma. We will also review and discuss the implications of immunosuppressives in SLE-related lymphoma and the role of mycophenolate mofetil in SLE-related primary CNS lymphoma development.

  19. Pancreatic fistula after central pancreatectomy: case series and review of the literature.

    Science.gov (United States)

    Zhou, Yan-Ming; Zhang, Xiao-Feng; Wu, Lu-Peng; Su, Xu; Li, Bin; Shi, Le-Hua

    2014-04-01

    Postoperative pancreatic fistula is one of the most common complications after pancreatectomy. This study aimed to assess the occurrence and severity of pancreatic fistula after central pancreatectomy. The medical records of 13 patients who had undergone central pancreatectomy were retrospectively studied, together with a literature review of studies including at least five cases of central pancreatectomy. Pancreatic fistula was defined and graded according to the recommendations of the International Study Group on Pancreatic Fistula (ISGPF). No death was observed in the 13 patients. Pancreatic fistula developed in 7 patients and was successfully treated non-operatively. None of these patients required re-operation. A total of 40 studies involving 867 patients who underwent central pancreatectomy were reviewed. The overall pancreatic fistula rate of the patients was 33.4% (0-100%). Of 279 patients, 250 (89.6%) had grade A or B fistulae of ISGPF and were treated non-operatively, and the remaining 29 (10.4%) had grade C fistulae of ISGPF. In 194 patients, 15 (7.7%) were re-operated upon. Only one patient with grade C fistula of ISGPF died from multiple organ failure after re-operation. Despite the relatively high occurrence, most pancreatic fistulae after central pancreatectomy are recognized a grade A or B fistula of ISGPF, which can be treated conservatively or by mini-invasive approaches.

  20. The Scholarship of Teaching and Learning: Transformation and Transgression

    Directory of Open Access Journals (Sweden)

    Laura Bolf-Beliveau, PhD

    2013-08-01

    Full Text Available Chapter Five of The Scholarship of Teaching and Learning Reconsidered (2011 suggests that traditional research scholarship methodology can inform and reform the ways in which we value and evaluate teaching. The authors discuss applying research methodology as way to complete this process. This article suggests that using theoretical frames, often used in qualitative methodology, creates another way to transform perceptions of the scholarship of teaching and learning. Two theoretical frames, transformative learning and critical consciousness, are explored and applied to the author’s own teaching experiences and discipline mandates.

  1. The versatile reverse flow sural artery neurocutaneous flap: A case series and review of literature

    Directory of Open Access Journals (Sweden)

    Fok Margaret

    2008-04-01

    Full Text Available Abstract Background Reverse flow sural neurocutaneous flap has been utilized more frequently during the past decade to cover vital structures around the foot and ankle area. The potential advantages are the relatively constant blood supply, ease of elevation and preservation of major vascular trunks in the leg. The potential disadvantages remain venous congestion, donor site morbidity and lack of sensation. Methods This descriptive case series was conducted at Queen Mary Hospital, Hong Kong, from 1997 to 2003. Ten patients having undergone reverse flow sural neurocutaneous flap were identified through medical records. There were six females (60% and four males (40%, with an average age of 59.8 years. The defects occurred as a result of trauma in five patients (50%, diabetic ulcers in four (40% and decubitus ulcer in one (10% paraplegic patient. The defect site included non weight bearing heel in four (40%, tendo Achilles in two (20%, distal tibia in two (20%, lateral malleolus in one (10% and medial aspect of the midfoot in one patient (10%. The maximum flap size harvested was 14 × 6 cm. Preoperative doppler evaluation was performed in all patients to identify perforators and modified plaster of paris boot was used in the post operative period. A detailed questionnaire was developed addressing variables of interest. Results There was no flap failure. Venous congestion was encountered in one case. The donor site was relatively unsightly but acceptable to all patients. The loss of sensation in the sural nerve distribution was transient in all patients. Conclusion Reverse sural artery flap remains to be the workhorse flap to resurface the soft tissue defects of the foot and ankle. Anastomosis of the sural nerve to the digital plantar nerve can potentially solve the issue of lack of sensation in the flap especially when used for weight bearing heel.

  2. Chagasic megacolon and large bowel neoplasms: case series and literature review

    Directory of Open Access Journals (Sweden)

    Maxwel Capsy Boga Ribeiro

    2011-12-01

    Full Text Available There is a clear association between chagasic megaesophagus and the esophageal cancer. On the other hand, the association between chagasic megacolon and intestinal neoplasm is uncommon. There are only a few cases described in literature. We selected two cases of colorectal adenocarcinoma associated with adenoma from 2000 to 2011, which are added to the four patients already described by this group. The mean age of the patients, was 68.5 years. Both had been submitted to surgical resection of the neoplasm. Survival rates ranged and were directly related to tumor staging at the time of diagnosis. In this context, we report our case series and reviwed the corresponding literature, especially the clinical and epidemiological aspects of this rare association.Há uma clara associação entre megaesôfago por doença de Chagas e o câncer esofágico. Ao contrário, tal relação, entre megacólon chagásico e neoplasias do intestino grosso é, reconhecidamente, incomum. Existem poucos casos relatados na literatura. Destacamos, entre 2000 e 2011, dois casos, sendo ambos adenocarcinomas colorretais e associados a adenomas, que se somam aos outros quatro já descritos por este grupo. A média de idade dos pacientes, foi de 68,5 anos. Todos foram submetidos à ressecção cirúrgica da neoplasia. A sobrevida foi variável e diretamente relacionada ao estádio do tumor no momento do diagnóstico. Dentro desse contexto, relatamos essa série de casos e revisamos a literatura correlata, com relação aos aspectos clínicos e epidemiológicos dessa rara associação.

  3. Adenoid cystic carcinoma of the breast: a case series of six patients and literature review.

    Science.gov (United States)

    Kim, Miso; Lee, Dae-Won; Im, Jin; Suh, Koung Jin; Keam, Bhumsuk; Moon, Hyeong-Gon; Im, Seock-Ah; Han, Wonshik; Park, In Ae; Noh, Dong-Young

    2014-01-01

    Adenoid cystic carcinoma (ACC) of the breast is a very rare and indolent tumor with a favorable prognosis, despite its triple-negative status. Due to its rarity, there has been no consensus regarding treatments, and treatment guidelines have not been established. Here, we report on six patients with ACC of the breast. All of the patients initially presented with localized disease and no axillary lymph node metastases. Although some of our patients developed local recurrence or distant metastases, all patients had a favorable clinical course, and to date, none of the patients has died from complications of her disease. Here, we described the clinicopathologic features of ACC of the breast and review the current literature.

  4. Acral lentiginous melanoma of the foot and ankle: A case series and review of the literature

    Directory of Open Access Journals (Sweden)

    Acland Katharine

    2008-09-01

    Full Text Available Abstract Background Acral lentiginous melanoma (ALM is an uncommon, cutaneous malignant tumour which may arise on the foot. Its relative rarity, atypical appearance and late presentation frequently serve as poor prognostic indicators. Methods At a tertiary skin tumour centre, a retrospective review was undertaken of all patients diagnosed with the tumour at the level of ankle or below. Results Over a six year period, 27 cases (20 female, 7 male were identified with positive histology confirming the disease. The age ranged from 35–96 years of age (mean 62.7 years. The majority of the cohort were white (59% with plantar lesions (62%. 33% of patients were initially were diagnosed incorrectly. The average time taken from the point of recognition, by the patient, to the lesion being correctly diagnosed was around 13.5 months. Conclusion Earlier diagnosis of ALM requires education at both a patient and practitioner level.

  5. Endoscopic Endonasal Approach in Skull Base Chondrosarcoma Associated with Maffucci Syndrome: Case Series and Literature Review.

    Science.gov (United States)

    Beer-Furlan, André; Balsalobre, Leonardo; Vellutini, Eduardo A S; Stamm, Aldo C

    2016-01-01

    Maffucci syndrome is a nonhereditary disorder in which patients develop multiple enchondromas and cutaneous, visceral, or soft tissue hemangiomas. The potential malignant progression of enchondroma into a secondary chondrosarcoma is a well-known fact. Nevertheless, chondrosarcoma located at the skull base in patients with Maffuci syndrome is a very rare condition, with only 18 cases reported in the literature. We report 2 other cases successfully treated through an expanded endoscopic endonasal approach and discuss the condition based on the literature review. Skull base chondrosarcoma associated with Maffucci syndrome is a rare condition. The disease cannot be cured, therefore surgical treatment should be performed in symptomatic patients aiming for maximal tumor resection with function preservation. The endoscopic endonasal approach is a safe and reliable alternative for the management of these tumors. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. Dapsone Therapy for Pustular Psoriasis: Case Series and Review of the Literature.

    Science.gov (United States)

    Sheu, Johanna S; Divito, Sherrie J; Enamandram, Monica; Merola, Joseph F

    2016-01-01

    Pustular psoriasis is an uncommon psoriasis variant, clinically characterized as small sterile pustules on an erythematous base. Evidence for therapy is lacking, and many currently employed systemic therapeutics carry risks of significant side effects, without specifically targeting disease etiology which includes the aggregation of neutrophils. We report therapy with the anti-neutrophil agent dapsone in 5 patients with pustular psoriasis and provide a brief review of the literature. Four patients responded to oral dapsone and 1 to topical dapsone therapy. All 5 patients had previously failed multiple topical and systemic treatments. In 2 cases, oral dapsone allowed for the discontinuation of other systemic agents. One patient stopped oral dapsone due to a side effect of sleep disturbance. Dapsone has a much safer side effect profile and may target the pathophysiology of pustular psoriasis more directly than many other systemic agents. As such, dapsone should be considered for the treatment of patients with pustular psoriasis. © 2015 S. Karger AG, Basel.

  7. Retroperitoneal fibrosis: case series of five patients and review of the literature

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    Shacahf Shiber

    2016-04-01

    Full Text Available ABSTRACT Chronic periaortitis (CP is an umbrella term used to describe a group of nosologically allied conditions that include idiopathic retroperitoneal fibrosis (Ormond's disease, inflammatory abdominal aortic aneurysm, and perianeurysmal retroperitoneal fibrosis. Retroperitoneal fibrosis encompasses a range of diseases characterized by the presence of a fibro-inflammatory tissue, which usually surrounds the abdominal aorta and the iliac arteries and extends into the retroperitoneum to envelop neighboring structures-ureters. Retroperitoneal fibrosis is generally idiopathic, but can also be secondary to the use of certain drugs, malignant diseases, infections, and surgery. Here we describe a 5 years follow up (2006-2011 of 5 patients admitted to our hospital with symptoms, laboratory, imaging and pathologic finding compatible with retroperitoneal fibrosis. We review our clinical course of our patient with respect to the literature.

  8. Mucoceles of the oral cavity: a large case series (1994-2008) and a literature review.

    Science.gov (United States)

    Re Cecconi, Dario; Achilli, Antonio; Tarozzi, Marco; Lodi, Giovanni; Demarosi, Federica; Sardella, Andrea; Carrassi, Antonio

    2010-07-01

    Evaluating data of patients affected by oral mucoceles, examined at the Unit of Oral Medicine and Pathology of the University of Milan between January 1994 and December 2008. Concise review on oral mucoceles and analysis of the clinical files of patients who underwent excisional biopsy (patient age, medical history, diagnosis, date and site of the biopsy, histopathological diagnosis and recurrences if any). During the period June 1994-December 2008, 158 mucoceles were observed (93 males and 65 females), with the most frequent site being the lower lip (53%) (p=0.001 by Fisher's test). The mean age of the patients was 31.9 years, with a peak of occurrence in the first four decades of life (75%). Mucoceles are lesions commonly seen in an oral medicine service, mainly affecting young people and lower lips.

  9. Recurrent Obscure Gastrointestinal Bleeding: Dilemmas and Success with Pharmacological Therapies. Case Series and Review

    Directory of Open Access Journals (Sweden)

    Majid Almadi

    2009-01-01

    Full Text Available The present article describes three difficult cases of recurrent bleeding from obscure causes, followed by a review of the pitfalls and pharmacological management of obscure gastrointestinal bleeding. All three patients underwent multiple investigations. An intervening complicating diagnosis or antiplatelet drugs may have compounded long-term bleeding in two of the cases. A bleeding angiodysplasia was confirmed in one case but was aggravated by the need for anticoagulation. After multiple transfusions and several attempts at endoscopic management in some cases, long-acting octreotide was associated with decreased transfusion requirements and increased hemoglobin levels in all three cases, although other factors may have contributed in some. In the third case, however, the addition of low-dose thalidomide stopped bleeding for a period of at least 23 months.

  10. Endodontic applications of cone beam computed tomography: case series and literature review

    Directory of Open Access Journals (Sweden)

    Francesc Abella

    2015-11-01

    Full Text Available Cone beam computed tomography (CBCT is a relatively new method that produces three-dimensional (3D information of the maxillofacial skeleton, including the teeth and their surrounding tissue, with a lower effective radiation dose than traditional CT scans. Specific endodontic applications for CBCT are being identified as the use of this technology becomes more common. CBCT has great potential to become a valuable tool for diagnosing and managing endodontic problems, as well as for assessing root fractures, apical periodontitis, resorptions, perforations, root canal anatomy and the nature of the alveolar bone topography around teeth. This article aims to review cone beam technology and its advantages over CT scans and conventional radiography, to illustrate current and future clinical applications in endodontic practice, and to highlight areas of further research of CBCT in endodontics. Specific case examples illustrate how treatment planning has changed with the images obtained with CBCT technology compared with only periapical radiography.

  11. Iatrogenic Cushing's syndrome and topical steroid therapy: case series and review of the literature.

    Science.gov (United States)

    Decani, Sem; Federighi, Veronica; Baruzzi, Elisa; Sardella, Andrea; Lodi, Giovanni

    2014-12-01

    Topical corticosteroids are considered first-line therapy in patients with chronic inflammatory oral mucosal diseases; among them, clobetasol propionate is one of the most widely used in oral medicine. Under physiological conditions, the transmucosal application is characterized by a significantly greater absorption than the skin application. Contrary to many publications about the side effects of topical corticosteroids in dermatology, few studies have investigated the systemic effects due to local application of these drugs on oral mucosa. Although topical steroid therapy for the management of oral diseases is generally associated with local adverse effects (candidiasis, stomatopyrosis, and hypogeusia), these drugs can also lead to systemic side effects, such as suppression of the hypothalamic-pituitary-adrenal axis and Cushing's syndrome. This review reports five cases of systemic adverse effects caused by clobetasol propionate topical treatment.

  12. Combined Intracapsular And Extracapsular Neck Of Femur Fractures Case Series, Literature Review And Management Recommendations.

    Science.gov (United States)

    Khan, Wasim; Williams, Rhodri; Hopwood, Sam; Agarwal, Sanjeev

    2017-01-01

    Concomitant ipsilateral intracapsular and extracapsular fractures of the femoral neck are rare injuries with only 14 cases described in the literature as single case reports. We present three cases that were successfully and uniquely treated by uncemented hip arthroplasties. Two patients underwent complex primary uncemented total hip replacements, and one patient underwent an uncemented bipolar fluted stem hemiarthroplasty. The level of bearing constraint varied between implants. After describing our cases we review the literature and make recommendations on the management of these injuries. We believe that these are significant injuries and best functional results can be achieved with an early diagnosis and patient-specific approach that can include a total hip replacement in appropriate cases.

  13. Peritonitis after gastrostomy tube replacement: a case series and review of literature.

    Science.gov (United States)

    Taheri, Mohammad R; Singh, Harminder; Duerksen, Donald R

    2011-01-01

    The placement of feeding gastrostomy (G) tubes through a percutaneous endoscopic gastrostomy (PEG) technique has become common because of its simplicity and safety. The majority of the serious complications are reported to occur within a few days of initial tube placement and happen in fewer than 3% of cases. Long-term reported complications of this procedure include occlusion or breakage of the G-tube, requiring reinsertion. This report describes the complication of intraperitoneal placement and the development of peritonitis after replacement of an established PEG tube and reviews the pertinent world literature. A retrospective review of cases of intraperitoneal insertion of replacement G-tubes was done as well as a Medline search for cases of intraperitoneal insertion of replacement G-tube or development of peritonitis after replacement tube insertion. Three new cases of inadvertent intraperitoneal insertion of a replacement G-tube in adult patients with mature tracts are reported. An additional 5 cases have been previously described in adults. Significant morbidity was associated with this complication, and 4 deaths were related to it. Methods used to determine whether the replacement G-tube was intragastric were not uniform. There have been few reports of intraperitoneal insertion of replacement G-tubes in patients with mature (>30 days) stoma sites. The cases presented in this report highlight for the clinician the importance of considering this complication, particularly if there are any difficulties with the reinsertion. Prospective studies are needed to determine the frequency of this complication and the optimal protocol for PEG replacement.

  14. Mucinous adenocarcinoma of the endometrium: case series and review of the literature.

    Science.gov (United States)

    Jalloul, Randa J; Elshaikh, Mohamed A; Ali-Fehmi, Rouba; Haley, Michael M; Yoon, Jiyoon; Mahan, Meridith; Munkarah, Adnan R

    2012-06-01

    Mucinous carcinoma of the endometrium (MCE) is a rare histologic type representing less than 5% of all endometrial carcinomas. The aim of the study was to describe our experience with MCE and determine its clinical outcome. After institutional review board approval, we performed a comprehensive retrospective review of medical records of patients with uterine adenocarcinoma who underwent surgical staging for MCE in 2 large academic centers between 1990 and 2009. Patients with 2009 International Federation of Gynecology and Obstetrics stages I to III were included. Patients' demographics and tumor characteristics were obtained and analyzed, including data on follow-up and survival. Thirty-one patients with MCE were identified for the study. Median age was 62 years (range, 43-91 years). All patients underwent surgical staging with lymph node evaluation. Patients' distribution by stage was as follows: 83.9% (n = 26) stage IA, 6.5% (n = 2) stage IIIA, and 9.7% (n = 3) stage IIIC1. Median follow-up was 62 months (range, 1-189 months). Only 30 patients received adjuvant platinum-based chemotherapy. No patients received adjuvant radiation treatment after hysterectomy. Only 4 patients had tumor recurrences with a median time to recurrence of 13.5 months (range, 8-30 months). Three patients with stage IIIC1 and one patient with stage IIIA had a diagnosis of pelvic recurrences. On univariate analysis, factors associated with recurrence were advanced stage (P ≤ 0.0001), deep myometrial invasion (P = 0.0199), lower uterine segment involvement (P = 0.0038), and grade II disease (P = 0.0013). Five-year relapse-free survival was 86.3%, and 5-year overall survival was 81.2%. Based on our study cohort, the outcome of patients with FIGO stage I to stage II MCE is excellent with surgical staging alone. However, patients with advanced stages may potentially benefit from adjuvant therapies. These findings need to be validated with other similar studies.

  15. Methylmalonic acidemia (MMA) in pregnancy: a case series and literature review.

    Science.gov (United States)

    Raval, Donna B; Merideth, Melissa; Sloan, Jennifer L; Braverman, Nancy E; Conway, Robert L; Manoli, Irini; Venditti, Charles P

    2015-09-01

    Women with inherited metabolic disorders, including those with previously life-limiting conditions such as MMA, are reaching child-bearing age more often due to advances in early diagnosis and improved pediatric care. Information surrounding maternal and fetal complications associated with the underlying disorders remains largely unexplored. Pregnancies affected by maternal MMA were ascertained through study 04-HG-0127 "Clinical and Basic Investigations of Methylmalonic Acidemia and Related Disorders" (clinicaltrials.gov identifier: NCT00078078) and via literature review. Prenatal and delivery records in study participants were reviewed. Seventeen pregnancies were identified in women with isolated MMA, including three abortions, one termination, and 13 completed pregnancies [three cases with cblA (four pregnancies), four cases of mut- (one cobalamin responsive, three non-responsive), five cases with unknown type of MMA]. Seventeen percent (3/17) of the pregnancies resulted in a first trimester abortion, while 38.5% (5/13) of the completed pregnancies resulted in preterm deliveries. A cesarean delivery rate of 53.8% (7/13) was noted among the cohort. Fetal distress or nonreassuring fetal status was the indication for 57% (4/7) cesarean deliveries. One patient was reported to have metabolic crisis as well as episodes of mild hyperammonemia. Malformations or adverse outcomes in the progeny were not observed. Although there have been a small number of pregnancies identified in women with MMA, the cumulative results suggest that the majority of pregnancies can be complicated by cesarean delivery and increased risk of prematurity. A pregnancy registry could clarify perinatal complications and define management approaches needed to ensure optimal maternal and fetal outcomes in this growing patient population.

  16. Incontinentia pigmenti--ophthalmological observation of a series of cases and review of the literature.

    LENUS (Irish Health Repository)

    O'Doherty, M

    2012-02-01

    AIM: The aims of this study were to make an inventory of the disease in Ireland, to acquire better knowledge of the relationship between genetic makeup and phenotypic ocular presentation and, finally, through literature review and personal experience, to establish clear guidelines on best practice in the management of children with this rare condition both in terms of screening and follow-up. METHODS: All patients who attended the dermatology and genetic clinic in Our Lady\\'s Hospital for Sick Children, Crumlin, with incontinentia pigmenti (IP) were contacted and invited to attend the eye clinic for ocular assessment. Children who were already attending the ophthalmic services before commencement of the study had their charts reviewed for assessment. RESULTS: 11 of 19 patients agreed to attend the clinic for ocular assessment. Of these patients, nine had genetic testing. The mean age of the patients at the examination was 8 years (3 months to 29 years). In 10 patients, IP was the result of a spontaneous mutation, whereas the condition was inherited from an affected mother in one patient. Of the 11 patients with IP, 5 have visually significant ocular findings (47%). We describe the case history of four of these children briefly to outline the severity of this condition. CONCLUSION: Our patients had a significant percentage of ocular abnormalities (47%). We have outlined an examination schedule for patients with and without retinal pathology and recommend fluorescein angiography in patients with retinal pathology to fully determine the extent of ischaemia. Like other studies, early treatment with peripheral retinal photocoagulation to reduce the risk of retinal detachment is recommended in this study.

  17. Immediate and early complications of the open Latarjet procedure: a retrospective review of a large consecutive case series.

    Science.gov (United States)

    Gartsman, Gary M; Waggenspack, Wame N; O'Connor, Daniel P; Elkousy, Hussein A; Edwards, T Bradley

    2017-01-01

    Immediate and early postoperative complications of the Latarjet procedure are not well documented in the literature. The purpose of this study was to report the procedure-related complications of our large consecutive case series of 3 surgeons at a single high-volume center. We conducted a retrospective chart review of 416 Latarjet procedures performed on 400 patients (16 patients had bilateral procedures) who underwent surgery by the 3 senior authors from October 2002 to July 2015. Immediate and early complications included hardware problems, infection, and neurologic injury. In addition, the patient's age and history of prior instability surgery were noted and evaluated as risk factors for complication. The overall complication rate was 5.0% (21 complications in 19 procedures). Thirteen neurologic injuries (3.1%) occurred to the axillary (7), musculocutaneous (4), and suprascapular (2) nerves, including 2 patients with multiple nerves affected. All but 2 patients had complete resolution of symptoms at time of last follow-up. Six infections (1.4%) developed, including 3 superficial infections treated with oral antibiotics and 3 deep infections requiring irrigation and débridement with intravenous antibiotics. Two early hardware-related complications (0.05%) were also noted. Increased age was associated with a higher complication rate. History of prior surgery was not associated with increased complications in our series. This study highlights the procedural complications of the Latarjet procedure. Neurologic injury was the most common complication in our series, with complete or near-complete recovery in 11 of 13 patients. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

  18. 25 CFR 166.903 - How can I get an agriculture scholarship?

    Science.gov (United States)

    2010-04-01

    ... degree-granting program at an accredited college or university. (g) Graduate scholarships are available... 25 Indians 1 2010-04-01 2010-04-01 false How can I get an agriculture scholarship? 166.903 Section... scholarship? (a) We may grant agriculture scholarships to Indians and Alaska Natives enrolled as full-time...

  19. And the Winner Is … : Inter-Rater Reliability among Scholarship Assessors

    Science.gov (United States)

    Johnston, Lucy; Schluter, Philip J.

    2017-01-01

    With increasing competition for postgraduate research scholarships, awarding processes demand attention and scrutiny. We examine inter-rater reliability for two prestigious New Zealand scholarships, the Shirtcliffe Fellowship and the Gordon Watson Scholarship. For each scholarship, five assessors (three academic; two non-academic) independently…

  20. 76 FR 16741 - Applications for New Awards; Erma Byrd Scholarship Program

    Science.gov (United States)

    2011-03-25

    ... Applications for New Awards; Erma Byrd Scholarship Program AGENCY: Office of Postsecondary Education, Department of Education. ACTION: Notice. Overview Information Erma Byrd Scholarship Program Notice inviting... Scholarship Program provides scholarships to individuals pursuing a course of study that will lead to a career...

  1. 42 CFR 405.380 - Collection of past-due amounts on scholarship and loan programs.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Collection of past-due amounts on scholarship and... Suspension of Payment, Recovery of Overpayments, and Repayment of Scholarships and Loans Repayment of Scholarships and Loans § 405.380 Collection of past-due amounts on scholarship and loan programs. (a) Basis and...

  2. 77 FR 14955 - DoD Information Assurance Scholarship Program (IASP)

    Science.gov (United States)

    2012-03-14

    ... of the Secretary 32 CFR Part 240 RIN 0790-AI28 DoD Information Assurance Scholarship Program (IASP... scholarship and grant program, known as the DoD Information Assurance Scholarship Program (IASP). The DoD IASP... executing an information assurance scholarship and grant program, known as the DoD Information Assurance...

  3. 75 FR 8316 - Office of Postsecondary Education; Overview Information; Erma Byrd Scholarship Program; Notice...

    Science.gov (United States)

    2010-02-24

    ... Office of Postsecondary Education; Overview Information; Erma Byrd Scholarship Program; Notice Inviting... Byrd Scholarship Program provides scholarships to individuals pursuing a course of study that will lead... scholarship to begin employment in a career position related to industrial health and safety no later than six...

  4. 42 CFR 62.5 - How is application made for a scholarship program award?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false How is application made for a scholarship program... FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL HEALTH SERVICE CORPS SCHOLARSHIP AND LOAN REPAYMENT PROGRAMS National Health Service Corps Scholarship Program § 62.5 How is application made for a scholarship program...

  5. 42 CFR 57.2205 - Priority for selection of scholarship recipients.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Priority for selection of scholarship recipients... GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2205 Priority for selection of scholarship...

  6. 42 CFR 62.3 - Who is eligible to apply for a scholarship program award?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Who is eligible to apply for a scholarship program... FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL HEALTH SERVICE CORPS SCHOLARSHIP AND LOAN REPAYMENT PROGRAMS National Health Service Corps Scholarship Program § 62.3 Who is eligible to apply for a scholarship program...

  7. 34 CFR 654.50 - How does an SEA disburse scholarship funds?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does an SEA disburse scholarship funds? 654.50... POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM How Does a Scholar Receive Scholarship Payments? § 654.50 How does an SEA disburse scholarship funds? (a) Except as provided...

  8. A Case Series of 4 Patients With Peristomal Pyoderma Gangrenosum: Review of Risk Factors and Treatment Response.

    Science.gov (United States)

    Turrión-Merino, L; Hermosa-Zarza, E; Miguel, L; Muñoz-Zato, E

    2016-04-01

    The literature on peristomal pyoderma gangrenosum (PPD) is scarce, and studies to date have included few patients. It is therefore difficult to determine the incidence of PPD, investigate risk factors, or evaluate the effectiveness of the different treatments available. We report on a series of 4 patients diagnosed with PPD at our hospital in 2013 and 2014, and review the clinical characteristics and responses to treatment. Three of the patients had inflammatory bowel disease and 1 had rectal cancer. Three patients responded favorably to initial treatment with 0.1% tacrolimus ointment (administered as monotherapy in 2 cases and combined with immunosuppressants in the other). However, on withdrawal of tacrolimus, the disease recurred in all 3 patients, requiring treatment reintroduction or modification. Copyright © 2015 Elsevier España, S.L.U. y AEDV. All rights reserved.

  9. Metabolic and Subjective Results Review of the Integrated Suit Test Series

    Science.gov (United States)

    Norcross, J.R.; Stroud, L.C.; Klein, J.; Desantis, L.; Gernhardt, M.L.

    2009-01-01

    Crewmembers will perform a variety of exploration and construction activities on the lunar surface. These activities will be performed while inside an extravehicular activity (EVA) spacesuit. In most cases, human performance is compromised while inside an EVA suit as compared to a crewmember s unsuited performance baseline. Subjects completed different EVA type tasks, ranging from ambulation to geology and construction activities, in different lunar analog environments including overhead suspension, underwater and 1-g lunar-like terrain, in both suited and unsuited conditions. In the suited condition, the Mark III (MKIII) EVA technology demonstrator suit was used and suit pressure and suit weight were parameters tested. In the unsuited conditions, weight, mass, center of gravity (CG), terrain type and navigation were the parameters. To the extent possible, one parameter was varied while all others were held constant. Tests were not fully crossed, but rather one parameter was varied while all others were left in the most nominal setting. Oxygen consumption (VO2), modified Cooper-Harper (CH) ratings of operator compensation and ratings of perceived exertion (RPE) were measured for each trial. For each variable, a lower value correlates to more efficient task performance. Due to a low sample size, statistical significance was not attainable. Initial findings indicate that suit weight, CG and the operational environment can have a large impact on human performance during EVA. Systematic, prospective testing series such as those performed to date will enable a better understanding of the crucial interactions of the human and the EVA suit system and their environment. However, work remains to be done to confirm these findings. These data have been collected using only unsuited subjects and one EVA suit prototype that is known to fit poorly on a large demographic of the astronaut population. Key findings need to be retested using an EVA suit prototype better suited to a

  10. Antipsychotic dose escalation as a trigger for Neuroleptic Malignant Syndrome (NMS: literature review and case series report

    Directory of Open Access Journals (Sweden)

    Langan Julie

    2012-11-01

    Full Text Available Abstract Background “Neuroleptic malignant syndrome” (NMS is a potentially fatal idiosyncratic reaction to any medication which affects the central dopaminergic system. Between 0.5% and 1% of patients exposed to antipsychotics develop the condition. Mortality rates may be as high as 55% and many risk factors have been reported. Although rapid escalation of antipsychotic dose is thought to be an important risk factor, to date it has not been the focus of a published case series or scientifically defined. Description We aimed to identify cases of NMS and review risk factors for its development with a particular focus on rapid dose escalation in the 30 days prior to onset. A review of the literature on rapid dose escalation was undertaken and a pragmatic definition of “rapid dose escalation” was made. NMS cases were defined using DSM-IV criteria and systematically identified within a secondary care mental health service. A ratio of titration rate was calculated for each NMS patient and “rapid escalators” and “non rapid escalators” were compared. 13 cases of NMS were identified. A progressive mean dose increase 15 days prior to the confirmed episode of NMS was observed (241.7 mg/day during days 1–15 to 346.9 mg/day during days 16–30 and the mean ratio of dose escalation for NMS patients was 1.4. Rapid dose escalation was seen in 5/13 cases and non rapid escalators had markedly higher daily cumulative antipsychotic dose compared to rapid escalators. Conclusions Rapid dose escalation occurred in less than half of this case series (n = 5, 38.5%, although there is currently no consensus on the precise definition of rapid dose escalation. Cumulative antipsychotic dose – alongside other known risk factors - may also be important in the development of NMS.

  11. Omalizumab in Severe Refractory Vernal Keratoconjunctivitis in Children: Case Series and Review of the Literature.

    Science.gov (United States)

    Doan, Serge; Amat, Flore; Gabison, Eric; Saf, Sarah; Cochereau, Isabelle; Just, Jocelyne

    2017-06-01

    Vernal keratoconjunctivis (VKC) is a severe form of pediatric ocular allergy, characterized by acute and chronic corneoconjunctival inflammation that may lead to visual sequelae. Although topical immunosuppressive drugs such as cyclosporine are usually effective, some severe forms may be refractory and require prolonged steroid therapy. Very few papers report the use of omalizumab in VKC in the literature. In the present study, we describe our clinical experience with omalizumab in severe VKC children. We retrospectively reviewed the files of four boys treated with omalizumab because of severe VKC, defined as persistent corneal inflammation despite continuous topical 2% cyclosporine and steroid eye drops. We also performed a literature review. Four boys, aged 7-13 years old, were treated. All children had asthma and one had severe lid eczema. Two patients had required intrapalpebral depot-steroid injections. Omalizumab was administered every 2 weeks by subcutaneous injections, at doses varying from 450 to 600 mg per injection. Three patients out of four responded to the treatment, with a decrease in global symptoms (median symptom rating decreasing from 89 to 29 on a 100-mm visual analog scale), frequency and in duration of the inflammatory flares, and also a decreased need for topical steroid. Their median clinical grade decreased from 4 to 3 (Bonini grading). However, the response was incomplete and they still had inflammatory corneoconjunctival flares despite continuous topical cyclosporine. On the other hand, asthma and lid eczema were completely controlled in these three patients. The fourth child did not respond to omalizumab and needed oral steroids for his VKC and his asthma. Noticeably, this latter patient did not have detectable sensitization to any allergen, contrary to the other cases. The treatment was stopped in this refractory case, but is still ongoing in all other cases, with a median duration of 33 months (range 16-42 months). In the

  12. Towards human exploration of space: The THESEUS review series on immunology research priorities

    Science.gov (United States)

    Frippiat, Jean-Pol; Crucian, Brian E; de Quervain, Dominique J-F; Grimm, Daniela; Montano, Nicola; Praun, Siegfried; Roozendaal, Benno; Schelling, Gustav; Thiel, Manfred; Ullrich, Oliver; Choukèr, Alexander

    2016-01-01

    Dysregulation of the immune system occurs during spaceflight and may represent a crew health risk during exploration missions because astronauts are challenged by many stressors. Therefore, it is crucial to understand the biology of immune modulation under spaceflight conditions in order to be able to maintain immune homeostasis under such challenges. In the framework of the THESEUS project whose aim was to develop an integrated life sciences research roadmap regarding human space exploration, experts working in the field of space immunology, and related disciplines, established a questionnaire sent to scientists around the world. From the review of collected answers, they deduced a list of key issues and provided several recommendations such as a maximal exploitation of currently available resources on Earth and in space, and to increase increments duration for some ISS crew members to 12 months or longer. These recommendations should contribute to improve our knowledge about spaceflight effects on the immune system and the development of countermeasures that, beyond astronauts, could have a societal impact. PMID:28725745

  13. Towards human exploration of space: The THESEUS review series on nutrition and metabolism research priorities.

    Science.gov (United States)

    Bergouignan, Audrey; Stein, T Peter; Habold, Caroline; Coxam, Veronique; O' Gorman, Donal; Blanc, Stéphane

    2016-01-01

    Nutrition has multiple roles during space flight from providing sufficient nutrients to meet the metabolic needs of the body and to maintain good health, to the beneficial psychosocial aspects related to the meals. Nutrition is central to the functioning of the body; poor nutrition compromises all the physiological systems. Nutrition is therefore likely to have a key role in counteracting the negative effects of space flight (e.g., radiation, immune deficits, oxidative stress, and bone and muscle loss). As missions increase in duration, any dietary/nutritional deficiencies will become progressively more detrimental. Moreover, it has been recognized that the human diet contains, in addition to essential macronutrients, a complex array of naturally occurring bioactive micronutrients that may confer significant long-term health benefits. It is therefore critical that astronauts be adequately nourished during missions. Problems of nutritional origin are often treatable by simply providing the appropriate nutrients and adequate recommendations. This review highlights six key issues that have been identified as space research priorities in nutrition field: in-flight energy balance; altered feeding behavior; development of metabolic stress; micronutrient deficiency; alteration of gut microflora; and altered fluid and electrolytes balance. For each of these topics, relevance for space exploration, knowledge gaps and proposed investigations are described. Finally, the nutritional questions related to bioastronautics research are very relevant to multiple ground-based-related health issues. The potential spin-offs are both interesting scientifically and potentially of great clinical importance.

  14. Infections Caused by Actinomyces neuii: A Case Series and Review of an Unusual Bacterium

    Directory of Open Access Journals (Sweden)

    Nathan Zelyas

    2016-01-01

    Full Text Available Background. Actinomyces neuii is a Gram-positive bacillus rarely implicated in human infections. However, its occurrence is being increasingly recognized with the use of improved identification systems. Objective. To analyse A. neuii infections in Alberta, Canada, and review the literature regarding this unusual pathogen. Methods. Cases of A. neuii were identified in 2013-2014 in Alberta. Samples were cultured aerobically and anaerobically. A predominant catalase positive Gram-positive coryneform bacillus with no branching was isolated in each case. Testing was initially done with API-CORYNE® (bioMérieux and isolates were sent to the Provincial Laboratory for Public Health for further testing. Isolates’ identities were confirmed by matrix-assisted laser desorption ionization time-of-flight mass spectrometry microbial identification system (MALDI-TOF MS MIS; bioMérieux and/or DNA sequencing. Results. Six cases of A. neuii infection were identified. All patients had soft tissue infections; typically, incision and drainage were done followed by a course of antibiotics. Agents used included cephalexin, ertapenem, ciprofloxacin, and clindamycin. All had favourable outcomes. Conclusions. While A. neuii is infrequently recognized, it can cause a diverse array of infections. Increased use of MALDI-TOF MS MIS is leading to increased detection; thus, understanding the pathogenicity of this bacterium and its typical susceptibility profile will aid clinical decision-making.

  15. Cochlear implantation in patients with enlarged vestibular aqueduct. A case series with literature review.

    Science.gov (United States)

    Clarós, Pedro; Fokouo, Jean Valentin F; Clarós, Andrés

    2017-05-01

    To report our institutional experience of the management of patients with enlarged vestibular aqueduct (EVA) and compare it to the literature. We carried out a retrospective review of patients' records from 1993 to 2015. The age, sex, associated malformations, relevant past medical history, genetic screening results, possible surgical incident, implant model and duration of follow- up, outcome in terms of Categories of Auditory Performance (CAP scores), and integration or resuming mainstream school or work were recorded. We had 11 patients (six boys and five girls) with EVA who underwent cochlear implant surgery in our center during the 22-year study period, out of a total of 827 implanted (1.3%). The mean age at surgery was 8.9 years ranging from 0.6 to 35 years. EVA was bilateral in 10 cases, isolated anatomical finding in seven cases, and associated with other malformations in four. Cochlear implantation was bilateral in five cases and unilateral in six. The mean follow- up duration was 48.3 months (range: 3-120). No postoperative complication was observed and all the patients could regain a serviceable hearing, attending normal school and working normally. EVA is frequently observed in the deaf population without an identifiable cause. The hearing loss is usually progressive and may result in cochlear implantation which has proved its efficiency in rehabilitating EVA patients.

  16. Pediatric malaria: 8-year case series in Atlanta, Georgia, and review of the literature.

    Science.gov (United States)

    Gutman, Julie; Guarner, Jeanette

    2010-01-01

    Although malaria is frequent in travelers, it is often misdiagnosed on initial presentation, especially in children. The objective of this study is to describe epidemiology, clinical and laboratory presentation, and treatment of children with malaria in the United States. We performed a retrospective review of 50 confirmed cases of malaria from two pediatric metropolitan hospitals in Atlanta, GA, from 2000 to 2008. Malarial smears were performed in 385 unique patients; 50 (12.6%) were positive. American children who had visited family and friends in malaria-endemic countries comprised 62% of our cases. Most cases visited Nigeria or Cameroon; all but three traveled to Africa. Three patients presented 8 to 12 months following travel. Plasmodium falciparum was diagnosed most frequently (72%). Most patients had low-level parasitemia ( 5%), no fatalities or long-term sequelae were seen. Malarial diagnosis can be difficult in children because parasitemia is usually below 1%. A high index of suspicion is required in patients who have traveled to Africa. © 2010 International Society of Travel Medicine.

  17. Tentorial dural arteriovenous fistula presenting as myelopathy: Case series and review of literature.

    Science.gov (United States)

    Gross, Robert; Ali, Rushna; Kole, Max; Dorbeistein, Curtis; Jayaraman, Mahesh V; Khan, Muhib

    2014-12-16

    Dural arteriovenous fistula (DAVF) is a rare type of cerebral arteriovenous malformation. Common presenting symptoms are related to hemorrhage. However, rarely these patients may present with myelopathy. We present two cases of DAVF presenting as rapidly progressive myelopathy. Two treatment options are available: microsurgical interruption of the fistula and endovascular embolization. These treatment options of DAVFs have improved significantly in the last decade. The optimal treatment of DAVFs remains controversial, and there is an ongoing debate as to whether primary endovascular or primary microsurgical treatment is the optimal management for these lesions. However, despite treatment a high percentage of patients are still left with severe disability. The potential for functional ambulation in patients with DAVF is related to the time of intervention. This emphasizes the important of early diagnosis and early intervention in DAVF. The eventual outcome may depend on several factors, such as the duration of symptoms, the degree of disability before treatment, and the success of the initial procedure to close the fistula. The usage of magnetic resonance imaging and selective angiography has significantly improved the ability to characterize DAVFs, however, these lesions remain inefficiently diagnosed. If intervention is delayed even prolonged time in rehabilitation does not change the grave prognosis. This review outlines the presentation, classication and management of DAVF as well as discussing patient outcomes.

  18. BCG-osis after BCG vaccination in immunocompromised children: Case series and review

    Directory of Open Access Journals (Sweden)

    Soheila Shahmohammadi

    2014-02-01

    Full Text Available Bacillus Calmette Guerin (BCG developed by Albert Calmette and Camille Guerin in France between 1908 and 1921 contained a live attenuated strain of Mycobacterium bovis and was administered worldwide to prevent tuberculosis. BCG vaccination is also administered at birth to all the newborns in Iran. Disseminated BCG infection after BCG vaccination is rare. Here in, we report 2 new cases of disseminated BCGinfection and review 15 additional cases identified from our previous retrospective study during a 5-year period from 2005-2010. All of these reported patients were vaccinated. Impaired immunity was detected in 10 cases (59% including severe combined immunodeficiency, chronic granulomatous disease, Mendelian susceptibility to mycobacterial disease, combined variable immunodeficiency, and HIV infection. Response to therapy was poor among those patients with immune deficiencies, but the overall mortality rate was 32.3%. Disseminated BCG infection is a rare but devastating complication of vaccination. Immune-compromised children are at high risk of developing BCG related complications including regional BCG-itis or disseminated disease; BCG-osis.

  19. Coronary artery aneurysms in acute coronary syndrome: case series, review, and proposed management strategy.

    Science.gov (United States)

    Boyer, Nathan; Gupta, Rajesh; Schevchuck, Alex; Hindnavis, Vindhya; Maliske, Seth; Sheldon, Mark; Drachman, Douglas; Yeghiazarians, Yerem

    2014-06-01

    Coronary artery aneurysm (CAA) is an uncommon clinical finding, with an incidence varying from 1.5%-4.9% in adults, and is usually considered a variant of coronary artery disease (CAD). CAA identified in the context of acute coronary syndrome (ACS) represents a unique management challenge, particularly if the morphology of the CAA is suspected to have provoked the acute clinical syndrome. CAA is associated with thrombus formation due to abnormal laminar flow, as well as abnormal platelet and endothelial-derived pathophysiologic factors within the CAA. Once formed, mural thrombus may potentiate the deposition of additional thrombus within aneurysmal segments. Percutaneous revascularization of CAA has been associated with complications including distal embolization of thrombus, no-reflow phenomenon, stent malapposition, dissection, and rupture. Presently, there are no formal guidelines to direct the management of CAA in patients presenting with ACS; controversies exist whether conservative, surgical, or catheter-based management should be pursued. In this manuscript, we present an extensive review of the existing literature and associated clinical guidelines, and propose a management algorithm for patients with this complex clinical scenario. Armed with this perspective, therapeutic decisions may be tailored to synthesize patient factors and preferences, individualized clinical assessment, and existing American Heart Association/American College of Cardiology guidelines for management of ACS.

  20. Pregnancy in women with gliomas: a case-series and review of the literature.

    Science.gov (United States)

    Zwinkels, Hanneke; Dörr, Joep; Kloet, Fred; Taphoorn, Martin J B; Vecht, Charles J

    2013-11-01

    The occurrence of pregnancy in women with brain tumors confronts both patients and physicians with difficult decision making at each stage of pregnancy. We studied the course of events of nine pregnancies in seven women with low-grade glioma in our hospital over a 10 year period. Five patients had a surgical resection, one a biopsy and one woman was followed by wait-and-see policy before pregnancy. In two women, a therapeutic abortion was carried out in the first trimester because of signs of progression, necessitating surgical removal of the tumor. In the other five women pregnancy had an uncomplicated course. Based on a literature review, we found 28 women diagnosed with a known glioma before becoming pregnant. All pregnancies but one, were uneventful and all women had a normal delivery, including the seven cases with exposure to chemotherapy and in whom healthy babies were born. A total of 75 pregnant women were identified in whom new onset glioma developed, which was high-grade in 56 %, and becoming symptomatic in 51 % during the third trimester, usually by focal neurological deficits. We conclude that in relation to pregnancy, low-grade gliomas are more often seen in women already known with a brain tumor, while high-grade gliomas represent more frequently a new onset phenomenon. Based on these observations, guidelines are given on initiation of antitumor therapy during pregnancy, seizure management, counseling on therapeutic abortion, and on the timing and choice of obstetrical interventions.

  1. Blastoschizomyces capitatus pulmonary infections in immunocompetent patients: case report, case series and literature review.

    Science.gov (United States)

    Tanabe, M B; Patel, S A

    2018-01-01

    Blastoschizomyces capitatus is an uncommon opportunistic yeast associated with infections in neutropaenic patients secondary to haematological malignancies, with a special predilection for the lungs. Globalisation and population migration impact on the epidemiology of infection with this organism but its effect on the immunocompetent population has rarely been described. We present here a case report, an overview of 11 other cases published between 2000 and 2016, and a comprehensive literature review of Blastoschizomyces pneumonia in the non-immunocompromised. The median age at diagnosis was 68 years (range 40-86 years) and more than half the cases reported a positive history of either current or past tobacco smoking. Six cases had either clinical or radiological evidence of chronic obstructive pulmonary disease and three had a history of prior treated tuberculosis. Fluconazole and itraconazole, alone or in combination, was the most utilised treatment. We conclude that unlike most other invasive yeast species, B. capitatus poses an infectious risk for immunocompetent patients, usually of middle to older age with risk factors for distorted lung architecture. Further research is warranted into the pathophysiology of Blastoschizomyces infections in the immunocompetent, including standardised treatment options.

  2. Our experience of carbon dioxide laser ablation of angiofibromas: Case series and literature review.

    Science.gov (United States)

    Ali, Faisal R; Mallipeddi, Raj; Craythorne, Emma E; Sheth, Nisith; Al-Niaimi, Firas

    2016-11-01

    Angiofibromas are one of the dermatological hallmarks of tuberous sclerosis. Various ablative treatments have been trialled and more recently topical rapamycin has been proposed. We present our experience of treatment of angiofibromas using carbon dioxide (CO2) laser ablation and provide a timely literature review. Nine patients were retrospectively identified as being treated with CO2 laser between 2009 and 2015. Three patients were male, six were female, median age at first treatment was 28 (range 15-49) years and the median number of treatments was two (range 1-17). Four of these patients could be contacted for a post-treatment telephone interview. All reported an improvement in appearance of angiofibromas following treatment and that they would recommend CO2 laser ablation to others. Three of the four reported recurrence of some lesions following treatment. The only side effect reported by one patient was transient hyperpigmentation. CO2 laser ablation appears to be a well-tolerated, efficacious treatment for angiofibromas with few long-term side effects.

  3. Lip leishmaniasis: a case series with molecular identification and literature review.

    Science.gov (United States)

    Mohammadpour, Iraj; Motazedian, Mohammad Hossein; Handjani, Farhad; Hatam, Gholam Reza

    2017-01-25

    Mucocutaneous leishmaniasis (MCL), a protozoan infectious disease, is very rare in Iran despite the endemicity of both cutaneous and visceral forms. It is transmitted by the Phlebotomus sand fly. The lip is considered one of the extraordinary sites. Lesions usually initiate with erythematous papules, slowly enlarges and then it ulcerates. The diagnosis of MCL encompasses epidemiological, clinical and laboratory aspects. Usually, the combination of some of these elements is necessary for the final diagnosis. So, lip leishmaniasis lesions can be challenging to diagnose. We presented seven rare cases of lip leishmaniasis. Tissue impression smear, culture, PCR and phylogenetic analysis were carried out for explicit diagnosis. Skin scraping investigation showed several Leishmania spp. amastigotes in the cytoplasm of macrophages. Culture examination was positive for Leishmania spp. PCR was positive for L. major, L. tropica, and L. infantum. Differential diagnosis includes orofacial granulomatosis, basal cell carcinoma, squamous cell carcinoma, and mesenchymal tumors. The cases were treated with systemic meglumine antimoniate (Glucantime(®)). No relapses were observed during 1 year of follow-up. Early detection of the infection are necessary in order to start effective treatment and prevent more serious complications. In this paper, we reported seven rare cases of lip leishmaniasis in Iran, emphasized the importance of clinical and diagnostic features of lesions, characterized the phylogenetic kinship of isolated parasites, and reviewed the literature on lip leishmaniasis.

  4. Treatment and results in pediatric traumatic hip dislocation: case series and review of the literature.

    Science.gov (United States)

    Başaran, Serdar Hakan; Bilgili, Mustafa Gökhan; Erçin, Ersin; Bayrak, Alkan; Öneş, Halil Nadir; Avkan, Mustafa Cevdet

    2014-11-01

    Six acute traumatic hip dislocations in pediatric patients were retrospectively analyzed. Types of dislocations, associated lesions, treatment methods, complications, and clinical and radiological outcomes were reviewed. Six child patients treated due to traumatic hip dislocation between 2007 and 2011 in our clinic were included in the study. While five of the patients were male, one was female; the average age was 8 years and 8 months. The mean follow-up was 25.2±10 months. There were posterior dislocations in five cases and transepiphyseal fractured dislocation in one case. Four cases were treated by closed reduction while two cases were treated with open reduction method. In the last control of the patients, asymmetric widening in the hip joint was found due to osteochondral fracture in one patient and coxa magna occurred in one patient. Avascular necrosis developed in one case with transepiphyseal fractured dislocation. Harris hip score evaluation was found excellent in five cases and bad in the case with fractured dislocation. Traumatic hip dislocation is a rare condition. It should be treated with preferably closed method as soon as possible. Repetitive reduction trials should be avoided. Open reduction should be performed to recognize accompanying lesions after advanced radiologic examinations such as computerized tomography and magnetic resonance imaging.

  5. The neuroimaging of Leigh syndrome: case series and review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Bonfante, Eliana; Riascos, Roy F. [The University of Texas Medical School at Houston, Department of Diagnostic and Interventional Imaging, Houston, TX (United States); Koenig, Mary Kay [The University of Texas Medical School at Houston, Department of Pediatrics, Division of Child and Adolescent Neurology, Mitochondrial Center of Excellence Leigh Clinic, Houston, TX (United States); Adejumo, Rahmat B.; Perinjelil, Vinu [The University of Texas Medical School at Houston, Department of Pediatrics, Division of Child and Adolescent Neurology, Houston, TX (United States)

    2016-04-15

    Leigh syndrome by definition is (1) a neurodegenerative disease with variable symptoms, (2) caused by mitochondrial dysfunction from a hereditary genetic defect and (3) accompanied by bilateral central nervous system lesions. A genetic etiology is confirmed in approximately 50% of patients, with more than 60 identified mutations in the nuclear and mitochondrial genomes. Here we review the clinical features and imaging studies of Leigh syndrome and describe the neuroimaging findings in a cohort of 17 children with genetically confirmed Leigh syndrome. MR findings include lesions in the brainstem in 9 children (53%), basal ganglia in 13 (76%), thalami in 4 (24%) and dentate nuclei in 2 (12%), and global atrophy in 2 (12%). The brainstem lesions were most frequent in the midbrain and medulla oblongata. With follow-up an increased number of lesions from baseline was observed in 7 of 13 children, evolution of the initial lesion was seen in 6, and complete regression of the lesions was seen in 3. No cerebral white matter lesions were found in any of the 17 children. In concordance with the literature, we found that Leigh syndrome follows a similar pattern of bilateral, symmetrical basal ganglia or brainstem changes. Lesions in Leigh syndrome evolve over time and a lack of visible lesions does not exclude the diagnosis. Reversibility of lesions is seen in some patients, making the continued search for treatment and prevention a priority for clinicians and researchers. (orig.)

  6. Hypokalemic rhabdomyolysis in congenital tubular disorders: a case series and a systematic review.

    Science.gov (United States)

    von Vigier, Rodo O; Ortisi, Maria Teresa; La Manna, Angela; Bianchetti, Mario G; Bettinelli, Alberto

    2010-05-01

    Hypokalemia is a recognized cause of rhabdomyolysis but very few reports document its association with inborn renal tubular disorders. We report our experience with hypokalemic rhabdomyolysis in 5 pediatric patients affected by inborn renal tubular disorders and the results of a careful review of the literature disclosing 9 further cases for a total of 14 patients (8 male and 6 female subjects, aged between 1.6 and 46, median 16 years). The inborn renal tubular disorders underlying rhabdomyolysis were classic distal renal tubular acidosis (n = 7), Gitelman syndrome (n = 5), classic Bartter syndrome (n = 1), and antenatal Bartter syndrome (n = 1). In 8 patients rhabdomyolysis followed an acute intestinal disease, an upper respiratory illness or the discontinuation of regular medication. Five patients experienced two or more episodes of rhabdomyolysis. In 10 patients the underlying renal tubular disorder was recognized concurrently with the episode of rhabdomyolysis or some weeks later. In conclusion some congenital renal tubular disorders predispose to hypokalemic rhabdomyolysis. Prevention of discontinuation of regular medication and electrolyte repair in the context of acute intercurrent illnesses might avoid the development of hypokalemic rhabdomyolysis.

  7. Case series on vascular malformation and their review with regard to terminology and categorization

    Directory of Open Access Journals (Sweden)

    Devi Charan Shetty

    2010-01-01

    Full Text Available Malformations of vascular nature originate as anomalies caused due to errors in vasculogenesis. These tumors are generally broadly classified into vascular tumors (hemangiomas and vascular malformations (venous malformations, arteriovenous malformations, lymphatic malformations. These descriptive tumors and malformations have been categorized based on the architectural assembly of vessels. Lymphangiomas are further subclassified microscopically into capillary, cavernous, cystic and lymphangioendothelioma, depending upon their histopathological features. Lymphatic malformations or lymphangiomas are uncommon congenital malformations of the lymphatic system, usually occurring in the head and neck region, characterized by collections of ectatic lymph vessels that form endothelial lined cystic spaces. Advancements in the knowledge of pathogenesis of such vascular malformations are continuously changing their treatment protocols. Early recognition is of utmost importance for initiation of proper treatment and avoiding serious complications. Hemangiolymphangioma is a variant of lymphangioma showing vascular component. Herewith, we present a case of vascular malformation diagnosed as hemangiolymphangioma histopathologically in a 9-year-old girl, along with a review of literature regarding its categorization.

  8. The Association of Salvia divinorum and Psychotic Disorders: A Review of the Literature and Case Series.

    Science.gov (United States)

    El-Khoury, Joseph; Sahakian, Nayiri

    2015-01-01

    The association of substance abuse and psychotic disorders is of interest to clinicians, academics, and lawmakers. Commonly abused substances, such as cannabis, cocaine, amphetamines, and alcohol, have all been associated with substance-induced psychosis. Hallucinogens can induce desired psychedelic effects and undesirable psychomimetic reactions. These are usually transient and resolve once the duration of action is over. Sometimes, these effects persist, causing distress and requiring intervention. This article focuses on the hallucinogenic substance Salvia divinorum, the use of which has been observed, particularly among youth worldwide. We present background information based on a review of the literature and on our own clinical encounters, as highlighted by two original case reports. We hypothesize that consumption of Salvia divinorum could be associated with the development of psychotic disorders. We propose that clinicians routinely inquire about the use of Salvia in patients with substance use disorders or psychotic illnesses. More research is required to assess any relationship between Salvia divinorum and psychosis. Additionally, we advocate increased public and medical awareness of this substance and other emerging drugs of abuse.

  9. Early Sherlockian scholarship: Non/fiction at play

    Directory of Open Access Journals (Sweden)

    Kate M. Donley

    2017-03-01

    Full Text Available Sherlockian scholarship is a display of intellect, wit, and canonical expertise that requires a cunning manipulation of a story world and of nonfiction. This playful style of writing defies easy classification in the terminology of fan and literary studies. Emerging in the early 20th century, Sherlockian scholarship had a tremendous surge in popularity in the late 1920s and early '30s in articles by renowned British and American authors, including Dorothy L. Sayers, Christopher Morley, Sir Desmond MacCarthy, Sir Sydney Castle Roberts, and Ronald A. Knox. The sustained popularity of Sherlockian scholarship owes much to these initial players, whose sparkling prose conjures a bygone era of repartee. In this study, I present a chronological survey of two early periods in Sherlockian scholarship to understand its poetics, popularity, generic identity, and contemporary relevance.

  10. Prestigious Goldwater Scholarships awarded to three Virginia Tech students

    OpenAIRE

    Sutphin, Michael D.

    2008-01-01

    Three outstanding Virginia Tech students, each with an impressive record of undergraduate research and leadership experience, have received highly competitive Barry M. Goldwater scholarships for the 2008-09 academic year.

  11. University Honors program awards scholarships to three outstanding sophomores

    OpenAIRE

    Williams, Meghan

    2007-01-01

    Virginia Tech's University Honors students have long been known for their outstanding academic achievements and service to the community, and three new recipients of sophomore scholarships are no exception.

  12. Retreating academics: creating spaces for the scholarship of ...

    African Journals Online (AJOL)

    , this paper explores particular spaces created to support academic engagement in the scholarship of teaching and learning: the space of writing retreats. The metaphor of 'tapestry' is used to capture the development of a complex conceptual ...

  13. Women in science & engineering and minority engineering scholarships : year 5.

    Science.gov (United States)

    2011-06-01

    Support will make scholarships available to minority and women students interested in engineering and science and will increase : significantly the number of minority and female students that Missouri S&T can recruit to its science and engineering pr...

  14. Women in science & engineering and minority engineering scholarships : year 4.

    Science.gov (United States)

    2010-04-01

    Support will make scholarships available to minority and women students interested in engineering and science and will increase : significantly the number of minority and female students that Missouri S&T can recruit to its science and engineering pr...

  15. Proposal to Reduce Sports Scholarships Assailed as Unfair.

    Science.gov (United States)

    Lederman, Douglas

    1987-01-01

    The National Collegiate Athletic Association's proposed reductions in scholarships, affecting most non-revenue sports but sparing big-time football, are widely criticized for their disproportionate effects on women and minority groups. (MSE)

  16. Schooling feeding versus scholarship program : which one is key to ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Schooling feeding versus scholarship program : which one is key to help children learn reading, writing and simple calculation skills?; final draft report. Pheakdey Em; Pheakdey Pheap. URI: http://hdl.handle.net/10625/54705. Date: 2013-10 ...

  17. Promoting Faculty Scholarship – An evaluation of a program for busy clinician-educators

    Directory of Open Access Journals (Sweden)

    Stacia Reader

    2015-04-01

    Full Text Available Background: Clinician educators face barriers to scholarship including lack of time, insufficient skills, and access to mentoring. An urban department of family medicine implemented a federally funded Scholars Program to increase the participants’ perceived confidence, knowledge and skills to conduct educational research. Method: A part-time faculty development model provided modest protected time for one year to busy clinician educators. Scholars focused on designing, implementing, and writing about a scholarly project. Scholars participated in skill seminars, cohort and individual meetings, an educational poster fair and an annual writing retreat with consultation from a visiting professor. We assessed the increases in the quantity and quality of peer reviewed education scholarship. Data included pre- and post-program self-assessed research skills and confidence and semi-structured interviews. Further, data were collected longitudinally through a survey conducted three years after program participation to assess continued involvement in educational scholarship, academic presentations and publications. Results: Ten scholars completed the program. Scholars reported that protected time, coaching by a coordinator, peer mentoring, engagement of project leaders, and involvement of a visiting professor increased confidence and ability to apply research skills. Participation resulted in academic presentations and publications and new educational leadership positions for several of the participants. Conclusions: A faculty scholars program emphasizing multi-level mentoring and focused protected time can result in increased confidence, skills and scholarly outcomes at modest cost.

  18. [Aplasia cutis congenita and antithyroid drugs during pregnancy: Case series and literature review].

    Science.gov (United States)

    Sachs, C; Tebacher-Alt, M; Mark, M; Cribier, B; Lipsker, D

    2016-01-01

    Aplasia cutis congenita (ACC) following in utero exposure to antithyroid drugs such as methimazole/carbimazole (MTZ/CMZ) has been reported since 1972. Though currently included in MTZ/CMZ embryopathy, it remains poorly characterized and is little discussed. Having seen two cases within a short period of time, we carried out a literature review and searched the French pharmacovigilance database for notification of cases. We performed a search of the literature in the Medline database using the following keywords: "aplasia cutis congenita", "birth skin defects", "pregnancy" and "drug". All articles reporting cases of ACC following in utero exposure to antithyroid drugs were included. All cases of ACC under antithyroid drugs reported to French pharmacovigilance centres were analysed. Three hundred and sixty-eight articles were retrieved and 31 were analysed, including a further 4, mentioned in selected articles, giving 59 cases of ACC under MTZ/CMZ reported in the literature and having an intrinsic accountability score of plausible or dubious. ACC was typically isolated, single, small in size, and localised on the median scalp area. Exposure occurred in the first weeks of gestation. There were 6 familial cases involving siblings. Ten ACC and MTZ/CMZ cases were reported to pharmacovigilance centres in France. Practitioners should be aware of ACC following MTZ/CMZ exposure in utero, whether it occurs in isolation or not. It is likely a teratogenic effect of MTZ/CMZ enhanced by a genetic predisposition. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  19. Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review.

    Science.gov (United States)

    Cooper, J J; Schatzberg, S J; Vernau, K M; Summers, B A; Porter, B F; Siso, S; Young, B D; Levine, J M

    2014-01-01

    Canine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder. Our objective was to describe histopathologically confirmed NME in dog breeds in which the condition has not been reported previously and to provide preliminary evidence that NME affects a wider spectrum of dog breeds than previously reported. Four dogs with NME. Archives from 3 institutions and from 1 author's (BS) collection were reviewed to identify histopathologically confirmed cases of NME in breeds in which the disease has not been reported previously. Age, sex, breed, survival from onset of clinical signs, and histopathologic findings were evaluated. Necrotizing meningoencephalitis was identified in 4 small dog breeds (Papillon, Shih Tzu, Coton de Tulear, and Brussels Griffon). Median age at clinical evaluation was 2.5 years. Histopathologic abnormalities included 2 or more of the following: lymphoplasmacytic or histiocytic meningoencephalitis or encephalitis, moderate-to-severe cerebrocortical necrosis, variable involvement of other anatomic locations within the brain (cerebellum, brainstem), and absence of detectable infectious agents. Until now, NME has only been described in 5 small dog breeds. We document an additional 4 small breeds previously not shown to develop NME. Our cases further illustrate that NME is not a breed-restricted disorder and should be considered in the differential diagnosis for dogs with signalment and clinical signs consistent with inflammatory brain disease. Copyright © 2013 by the American College of Veterinary Internal Medicine.

  20. Review of osteochondroma of mandibular condyle and report of a case series.

    Science.gov (United States)

    Roychoudhury, Ajoy; Bhatt, Krushna; Yadav, Rahul; Bhutia, Ongkila; Roychoudhury, Sunanda

    2011-11-01

    To present a retrospective analysis of 10 cases of osteochondroma of the mandibular condyle (operated between 1993 and 2009) with respect to age, gender, site of the pathology, treatment modality and recurrence, with review of literature. Medical records with x-rays, computed tomography scans, and bone scans of all histologically proven osteochondroma of mandibular condyle cases operated between 1993 and 2009 were retrieved and examined. The data were tabulated and analyzed. There were 8 males and 2 females, with a right:left ratio of 2.3:1. Age range was 18 to 45 years with a mean of 29.4 years. Seven of 10 were superomedial in location. Six patients were treated by conservative condylectomy, whereas 4 required total condylectomy. In all cases, a preauricular with extended temporal approach was used. In the follow-up period ranging from 1 year to 13 years, there was no recurrence. Mandibular condylar osteochondroma is thought to be a relatively rare lesion with only 90 cases documented in the English language literature to date. Gradual facial asymmetry over the years is the most striking feature. Two types are identified: those causing growth potential in mandible causing bowing of ipsilateral body and requiring gnathic correction after excision of tumor, and others growing as tumors superior or superomedial to condyle without causing much growth in the mandible, requiring only excision and automatic swing back to correct asymmetry. Both the procedures---conservative condylectomy and the total condylectomy---are curative. The decision, however, depends on how much swing of mandible is required postsurgery for correction of asymmetry and occlusion. Copyright © 2011 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  1. Therapeutic plasmapheresis for hypertriglyceridemia-associated acute pancreatitis: case series and review of the literature.

    Science.gov (United States)

    Joglekar, Kiran; Brannick, Ben; Kadaria, Dipen; Sodhi, Amik

    2017-04-01

    Severe hypertriglyceridemia (HTG) is the third leading cause of acute pancreatitis (AP) in the United States. The current standard of care includes management of HTG using pharmacological therapy. More recently, plasmapheresis has been proposed as a therapeutic tool for decreasing triglyceride (TG) levels, especially in critically ill patients. Few studies are available to ascertain overall benefits of plasmapheresis over traditional management. To analyze the outcomes of patients treated with plasmapheresis for severe HTG-associated pancreatitis. We conducted a retrospective chart review of three patients with severe HTG- associated (TGs greater than 1000 mg/dl; 11.29 mmol/l) AP at the Methodist University Hospital. All the patients underwent plasmapheresis as part of their treatment. The average TG level before plasmapheresis was 3532 mg/dl (range: 2524-4562 mg/dl; 39.9 mmol/l; range: 28.5-51.6 mmol/l). All patients made a full recovery, with a significant improvement in TG levels after plasmapheresis. The mean number of sessions was 1.3 (range 1-2), and mean TG level after plasmapheresis was 1051 mg/dl (range: 509-1771 mg/dl; 11.9 mmol/l; range: 5.8-20 mmol/l). After the first session, the average reduction of TG level was 2481 mg/dl (range 753-3750 mg/dl; 28 mmol/l; range: 8.5-42.4 mmol/l) or approximately 70%. None of the patients developed complications related to plasmapheresis. Plasmapheresis can be an effective and rapid treatment option in patients with severe HTG and complications. However, further research, including randomized controlled studies, is necessary.

  2. Carbimazole embryopathy in a Chinese population: case series and literature review.

    Science.gov (United States)

    Ting, Yuen Ha; Zhou, Yan; Lao, Terence T

    2013-04-01

    The data in the literature suggests that Methimazole (MMI)/Carbimazole (CMZ) embryopathy is rare. This study examined the incidence of CMZ embryopathy in the Hong Kong Chinese population and the factors associated with its development. Of the 145 pregnant women with hyperthyroidism managed from 2008 to 2010, 29 (20%) had taken CMZ during pregnancy. The presence and details of birth defects, the dosage of CMZ, and the period of exposure during pregnancy were examined in these 29 pregnancies. All cases of CMZ embryopathy in the English literature were reviewed in the same way. Of the 27 babies (93.1%) with known outcome, 3 had aplasia cutis and 1 had an omphalocele in addition, and 1 affected baby had a sibling with aplasia cutis and patent vitellointestinal duct. The incidence of CMZ embryopathy in our study group is 11.1%. Amongst the 21 cases of CMZ embryopathy in the literature, 85% were exposed to a CMZ dosage of ≥20 mg/day, and the minimum duration of exposure being 7 weeks from last menstrual period. The most common abnormality is ectodermal anomaly (62%), followed by oro-nasal anomaly (48%), facial dysmorphism (38%), gastrointestinal anomaly (33%) and abdominal wall defect (19%). There was no relationship between the type of abnormality and the dosage or duration of exposure to CMZ. The incidence of CMZ embryopathy in our study group is 11.1%. Critical factors for its development are exposure to a CMZ dosage of ≥20 mg/day before 7 weeks of gestation. Genetic susceptibility may also play a role. Copyright © 2013 Wiley Periodicals, Inc.

  3. Microsurgical treatment of sacral perineural (Tarlov) cysts: case series and review of the literature.

    Science.gov (United States)

    Burke, John F; Thawani, Jayesh P; Berger, Ian; Nayak, Nikhil R; Stephen, James H; Farkas, Tunde; Aschyan, Hovik John; Pierce, John; Kanchwala, Suhail; Long, Donlin M; Welch, William C

    2016-05-01

    OBJECTIVE Tarlov cysts (TCs) occur most commonly on extradural components of the sacral and coccygeal nerve roots. These lesions are often found incidentally, with an estimated prevalence of 4%-9%. Given the low estimated rates of symptomatic TC and the fact that symptoms can overlap with other common causes of low-back pain, optimal management of this entity is a matter of ongoing debate. Here, the authors investigate the effects of surgical intervention on symptomatic TCs and aim to solidify the surgical criteria for this disease process. METHODS The authors performed a retrospective review of data from consecutive patients who were surgically treated for symptomatic TCs from September 2011 to March 2013. Clinical evaluations and results from surveying pain and overall health were used. Univariate statistical analyses were performed. RESULTS Twenty-three adults (4 males, 19 females) who had been symptomatic for a mean of 47.4 months were treated with laminectomy, microsurgical exposure and/or imbrication, and paraspinous muscle flap closure. Eighteen patients (78.3%) had undergone prior interventions without sustained improvement. Thirteen patients (56.5%) underwent lumbar drainage for an average of 8.7 days following surgery. The mean follow-up was 14.4 months. Univariate analyses demonstrated that an advanced age (p = 0.045), the number of noted perineural cysts on preoperative imaging (p = 0.02), and the duration of preoperative symptoms (p = 0.03) were associated with a poor postoperative outcome. Although 47.8% of the patients were able to return to normal activities, 93.8% of those surveyed reported that they would undergo the operation again if given the choice. CONCLUSIONS This is one of the largest published studies on patients with TCs treated microsurgically. The data suggest that patients with symptomatic TCs may benefit from open microsurgical treatment. Although outcomes seem related to patient age, duration of symptoms, and extent of disease

  4. Bea Scoring System: Selecting the Right Person for Scholarship

    OpenAIRE

    Sharif, Shamshuritawati; Ismail, Suzilah; Ahmad, Yuhaniz; Khalid, Ruzelan; Omar, Mohd. Faizal; Zain, Zakiyah

    2015-01-01

    Disability may involve visual disability, physical disability, learning disorder, speech disorder, mental disorder and others various disabilities. This situation can reduce the quality of life, and causes clear drawback to that person. Due to this, in many countries, there are scholarships for students with disability, and students with disability parents. Universiti Utara Malaysia also provides a scholarship known as Bestari Education Award (BEA) scheme to assist poor students with disabili...

  5. The influence of marketing scholarship's legacy on nonprofit marketing

    OpenAIRE

    Walter Wymer

    2013-01-01

    This inquiry contributes to the literature on the development of “nonprofit marketing thought” by describing how the field’s early period established a legacy effect on nonprofit marketing scholarship to the present day. This qualitative work uses a wide variety of sources from a protracted historical period in order to more fully inform a perspective on the relevant issues that have influenced the development of nonprofit marketing scholarship. The investigation suggests that, although the d...

  6. Use of spinal cord stimulation in the treatment of phantom limb pain: case series and review of the literature.

    Science.gov (United States)

    Viswanathan, Ashwin; Phan, Phillip Cuong; Burton, Allen Wade

    2010-01-01

    Despite technical advances in spinal cord stimulation (SCS), there is a paucity of recent literature regarding SCS for phantom limb pain. Between January 2003 and May 2008, four patients at M.D. Anderson Cancer Center underwent SCS for intractable phantom limb pain. A retrospective chart review was performed to assess outcomes and complications. A PubMed search was performed to review previously published series regarding the efficacy of SCS for phantom limb pain. Postoperatively, all patients subjectively reported excellent pain relief (>80%). Patients were all followed with the Brief Pain Inventory. Patients 1 to 3 each reported at wo-point decrease in their usual amount of pain using the numerical rating scale. Patient 4's numerical pain scale was unchanged. When using an 11-point scale to assess other symptomology along 10 dimensions, patients 1 to 3 demonstrated a decrease in their total symptom score by 13, 14, and 4 points, respectively. Patient 4 reported an increase by 5 points in his total symptom score. With regard to complications, patient 2 developed an allergic dermatitis to the generator requiring revision with a polyfluoroethylene (GorTex) pouch. Patient 3 developed a surgical site infection after an implantable pulse generator change. Patients 2 to 4 were very satisfied with their stimulator and would choose to undergo implantation again, with patient 1 having an equivocal response. For selected patients who have not obtained adequate relief with medical management, SCS for phantom limb pain can prove an effective intervention.

  7. Exploring community faculty members' engagement in educational scholarship.

    Science.gov (United States)

    Law, Marcus; Wright, Sarah; Mylopoulos, Maria

    2016-09-01

    To obtain a deeper understanding of community faculty members' perceptions about engagement in educational scholarship. One-on-one semistructured interviews that were audiorecorded, transcribed verbatim, and subsequently analyzed. Toronto, Ont. Purposive, theoretical sample of 8 physician faculty members at the University of Toronto. Interview transcripts were analyzed using a grounded theory approach. Emergent themes were identified by the research team through a process of constant comparative analysis. Community faculty members identified themselves professionally as clinicians and teachers, and they did not see themselves as scholars in medical education. While they believed that educational scholarship was important for the field more broadly, they did not see the personal or professional value of being involved. This attitude stemmed from the perception that there was not a direct link between scholarly activity and improvement in teaching or patient care. Instead, participants viewed scholarly activity as a mode of career advancement rather than practice improvement. Furthermore, they equated educational scholarship with clinical research, thereby excluding themselves from participation in scholarly activities. When developing strategies to engage community faculty members in educational scholarship, it is important to consider the implications of members' professional identity, as well as implicit models of scholarship. To expand the concept of educational scholarship beyond research activities, additional scholarly contributions need to be supported, recognized, and valued. Copyright© the College of Family Physicians of Canada.

  8. A Case Review Series of Christiana Care Health System’s Experience with Negative Pressure Wound Therapy Instillation

    Science.gov (United States)

    Gallagher, Kathy E; Tinkoff, Glen H; Cipolle, Mark

    2016-01-01

    Acute and chronic wounds afflict a multitude of patients to varying degrees. Wound care treatment modalities span the spectrum of technological advancement and with that differ greatly in cost. Negative pressure wound therapy (NPWT) can now be combined with instillation and dwell time (NPWTi-d). This case review series of 11 patients in a community hospital setting provides support for the utilization of NPWTi-d. Additionally, current literature on the use of NPWTi-d in comparison to NPWT will be reviewed.  We highlight three specific cases. The first case is a 16-year-old male who was shot in the left leg. He suffered a pseudoaneurysm and resultant compartment syndrome. This required a fasciotomy and delayed primary closure. To facilitate this, NPWTi-d was employed and resulted in a total of four operative procedures before closure 13 days after admission. Next, a 61-year-old uncontrolled diabetic female presented with necrotizing fasciitis of the lower abdomen and pelvis. She underwent extensive debridement and placement of NPWTi-d with Dakin’s solution. A total of four operative procedures were performed including delayed primary closure six days after admission. Finally, a 48-year-old female suffered a crush injury with internal degloving. NPWTi-d with saline was utilized until discharge home on postoperative day 12. NPWTi-d, when compared to NPWT, has been reported to lead to a decrease in time to operative closure, hospital length of stay, as well as operative procedures required. The cost-benefit analysis in one retrospective review noted a $1,400 savings when these factors were taken into account. This mode of wound care therapy has significant benefits that warrant the development of a prospective randomized controlled trial to further define the improvement in quality-of-life provided to the patient and the reduction of potential overall healthcare costs. PMID:27980886

  9. [The Perspectives and Expectations of New Nursing Graduates Regarding the Hospital-Based Nursing Students Scholarship].

    Science.gov (United States)

    Chen, Kuan-Ling; Tsai, Yun-Fang; Shao, Jung-Hua; Shyu, Yea-Ing

    2016-10-01

    The hospital-based scholarship is a relatively recent incentive used by hospitals to recruit new nursing graduates. Few studies have explored the impact of these scholarship programs on hospital recruitment. To explore the perspectives and expectations of new nursing graduates on the application of a hospital-based scholarship for nursing students. This study used a qualitative research approach. Purposive sampling was used to recruit 20 new nursing graduates from one university in northern Taiwan in 2013. Content analysis was applied to analyze the data. Two themes were identified by participants who had applied for a hospital-based scholarship: "aspire to be a nursing-scholarship recipient and work towards this aspiration" and "look forward to receiving a nursing-scholarship and imagine possible features of the future life." One theme was identified by participants who had not applied for a hospital-based scholarship: "agree with the policy of hospital-based scholarship but resist the restrictions on their life." Although both groups agreed that the scholarship program helped relieve financial stresses, participants who had applied for the scholarship tended to hold positive and aggressive attitudes towards the nursing scholarship. Conversely, participants who had not applied for the scholarship did so due to the perceived conflicts between the scholarship and their career plans. It is recommended to consider providing career-planning assistance to new graduates and to arrange that students who sign a scholarship contract have their clinical practice in their working unit in order to improve adaptation.

  10. Koers and the ideal of Christian scholarship

    Directory of Open Access Journals (Sweden)

    Daniël F.M. Strauss

    2012-10-01

    Full Text Available Commemorating the 75-year existence of the journal Koers is connected to the Reformational tradition, from Calvin to Kuyper, Stoker, Dooyeweerd and Vollenhoven – all thinkers who realised that the biblical starting point of life indeed touches the heart, the religious root, of humankind and therefore cannot remain restricted to church life and religion in its narrow sense, but must come to expression in all walks of life. This awareness was a fruit of the Christian worldview and lifeview which currently is confronted by the Big Bang claims and by neo-Darwinism – both movements taking on cultic dimensions with an intolerance towards everyone who does not accept their perspective. Their attitude generated serious reactions on two websites, the impact of which was discussed in this article. Some problems entailed in Darwinism and physicalistic materialism were highlighted, before attention was given to the status of natural laws and normative principles. Particular attention was given to the elimination of God’s law and the way in which modern Humanism explored the two cornerstones of modern nominalism, up to the point where human understanding was elevated to become the a priori formal law-giver of nature. This legacy was continued both by the later developments within the Baden school of neo-Kantian thought and Postmodernism,which is placed within the context of the three succeeding epistemic ideals of the past three centuries. Rationality can only fulfil its true calling when it accounts for the cohering diversity within reality without becoming a victim of any form of reductionism – and by following this guiding star, Koers will continue to strengthen its invaluable contribution to the advancement of Christian scholarship.

  11. The contribution of Nintendo Wii Fit series in the field of health: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Julien Tripette

    2017-09-01

    Full Text Available Background Wii Fit was originally designed as a health and fitness interactive training experience for the general public. There are, however, many examples of Wii Fit being utilized in clinical settings. This article aims to identify the contribution of Wii Fit in the field of health promotion and rehabilitation by: (1 identifying the health-related domains for which the Wii Fit series has been tested, (2 clarifying the effect of Wii Fit in those identified health-related domains and (3 quantifying this effect. Method A systematic literature review was undertaken. The MEDLINE database and Games for Health Journal published content were explored using the search term “Wii-Fit.” Occurrences resulting from manual searches on Google and material suggested by experts in the field were also considered. Included articles were required to have measurements from Wii Fit activities for at least one relevant health indicator. The effect of Wii Fit interventions was assessed using meta-analyses for the following outcomes: activity-specific balance confidence score, Berg balance score (BBC and time-up-and-go test (TUG. Findings A total of 115 articles highlighted that the Wii Fit has been tested in numerous healthy and pathological populations. Out of these, only a few intervention studies have focused on the prevention of chronic diseases. A large proportion of the studies focus on balance training (N = 55. This systematic review highlights several potential benefits of Wii Fit interventions and these positive observations are supported by meta-analyses data (N = 25. For example, the BBC and the TUG respond to a similar extend to Wii Fit interventions compared with traditional training. Conclusion Wii Fit has the potential to be used as a rehabilitation tool in different clinical situations. However, the current literature includes relatively few randomized controlled trials in each population. Further research is therefore required.

  12. Case Series Review

    African Journals Online (AJOL)

    open registry

    pillow under their heads. Subarachnoid anaesthesia for caesarean section was, however, performed with the patient supported in the sitting position and then turned into the horizontal position but with the pelvis wedged to keep it tilted immediately after injection. Oxygen was given to all the mothers during the operation.

  13. A alimentação do trabalhador no Brasil: um resgate da produção científica nacional Worker diet in Brazil: a review of Brazilian scholarship on the topic

    Directory of Open Access Journals (Sweden)

    Maria da Purificação Nazaré Araújo

    2010-12-01

    Full Text Available Empreende uma revisão de literatura sobre a alimentação do trabalhador no Brasil, questão importante para a saúde dos trabalhadores. Pretende oferecer elementos que permitam reflexão acerca do tema, procurando entender, sob uma perspectiva histórica, o tratamento que lhe foi dado. A pesquisa bibliográfica baseou-se sobretudo na Scientific Electronic Library On-line, cujos artigos sobre o tema foram analisados sem restrições quanto ao ano de sua publicação. Constatou-se, entre outros resultados, que o tema é rarefeito nos estudos de saúde do trabalhador, e que na nutrição as investigações são poucas, concentradas no Programa de Alimentação do Trabalhador, predominantemente de natureza quantitativa e desconsiderando a categoria 'processo de trabalho' nas análises.Diet is a vital health question for workers. This review of the related literature sought to identify the elements that could contribute to an examination of the topic and help ascertain how it has been approached from a historical perspective. Our bibliographic research was based primarily on the Scientific Electronic Library On-line, from which pertinent articles were selected for analysis, without regard to year of publication. Among other findings, studies on worker health proved scarce; moreover, the few studies that have explored nutrition focus on the Worker's Food Program, primarily from a quantitative perspective and without taking the category of 'work process' into account in their analyses.

  14. Resection of primary leiomyosarcoma of the inferior vena cava (IVC) with reconstruction: a case series and review of the literature.

    Science.gov (United States)

    Wachtel, Heather; Jackson, Benjamin M; Bartlett, Edmund K; Karakousis, Giorgos C; Roses, Robert E; Bavaria, Joseph E; Fraker, Douglas L

    2015-03-01

    Leiomyosarcoma of the inferior vena cava (IVC) is a rare tumor which presents a unique surgical challenge. We present a series of six cases of leiomyosarcoma resection performed with IVC reconstruction. Retrospective chart review was performed for patients undergoing initial operative resection of primary leiomyosarcoma with IVC reconstruction, at a tertiary care center. Between 2005-2013, six patients underwent resection with reconstruction. Half were female, and the mean age at presentation was 57 ± 15.4 years. Three patients required en bloc resection with adjacent organs. Three patients were resected on venovenous bypass, and one on cardiopulmonary bypass. Three underwent IVC patch repair (bovine pericardium, n = 2; saphenous vein, n = 1), and three had IVC reconstruction with graft (Dacron, n = 1; PTFE, n = 1; aortic homograft, n = 1). All achieved grossly negative margins. Median disease-free survival was 34 months (IQR 7-52 months), and median disease-specific survival was 51 months (IQR 20-108). Five year disease-free and disease-specific survival rates were 30% and 66.7%, respectively. Leiomyosarcomas of the IVC present a technical challenge to the surgeon. Careful preoperative workup and a collaborative team consisting of experienced cardiac and vascular surgeons and surgical oncologists can allow for a safe and successful operation despite extensive tumor involvement. © 2014 Wiley Periodicals, Inc.

  15. The Benefits of Peer Review and a Multisemester Capstone Writing Series on Inquiry and Analysis Skills in an Undergraduate Thesis.

    Science.gov (United States)

    Weaver, K F; Morales, V; Nelson, M; Weaver, P F; Toledo, A; Godde, K

    2016-01-01

    This study examines the relationship between the introduction of a four-course writing-intensive capstone series and improvement in inquiry and analysis skills of biology senior undergraduates. To measure the impact of the multicourse write-to-learn and peer-review pedagogy on student performance, we used a modified Valid Assessment of Learning in Undergraduate Education rubric for Inquiry and Analysis and Written Communication to score senior research theses from 2006 to 2008 (pretreatment) and 2009 to 2013 (intervention). A Fisher-Freeman-Halton test and a two-sample Student's t test were used to evaluate individual rubric dimensions and composite rubric scores, respectively, and a randomized complete block design analysis of variance was carried out on composite scores to examine the impact of the intervention across ethnicity, legacy (e.g., first-generation status), and research laboratory. The results show an increase in student performance in rubric scoring categories most closely associated with science literacy and critical-thinking skills, in addition to gains in students' writing abilities. © 2016 K. F. Weaver et al. CBE—Life Sciences Education © 2016 The American Society for Cell Biology. This article is distributed by The American Society for Cell Biology under license from the author(s). It is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  16. Visual loss in HIV-associated cryptococcal meningitis: A case series and review of the mechanisms involved

    Directory of Open Access Journals (Sweden)

    Anand Moodley

    2015-04-01

    Full Text Available Permanent visual loss is a devastating yet preventable complication of cryptococcal meningitis. Early and aggressive management of cerebrospinal fluid pressure in conjunction with antifungal therapy is required. Historically, the mechanisms of visual loss in cryptococcal meningitis have included optic neuritis and papilloedema. Hence, the basis of visual loss therapy has been steroid therapy and intracranial pressure lowering without clear guidelines. With the use of high-resolution magnetic resonance imaging of the optic nerve, an additional mechanism has emerged, namely an optic nerve sheath compartment syndrome (ONSCS caused by severely elevated intracranial pressure and fungal loading in the peri-optic space. An improved understanding of these mechanisms and recognition of the important role played by raised intracranial pressure allows for more targeted treatment measures and better outcomes. In the present case series of 90 HIV co-infected patients with cryptococcal meningitis, we present the clinical and electrophysiological manifestations of Cryptococcus-induced visual loss and review the mechanisms involved.

  17. Visual loss in HIV-associated cryptococcal meningitis: A case series and review of the mechanisms involved

    Directory of Open Access Journals (Sweden)

    Anand Moodley

    2015-10-01

    Full Text Available Permanent visual loss is a devastating yet preventable complication of cryptococcal meningitis. Early and aggressive management of cerebrospinal fluid pressure in conjunction with antifungal therapy is required. Historically, the mechanisms of visual loss in cryptococcal meningitis have included optic neuritis and papilloedema. Hence, the basis of visual loss therapy has been steroid therapy and intracranial pressure lowering without clear guidelines. With the use of high-resolution magnetic resonance imaging of the optic nerve, an additional mechanism has emerged, namely an optic nerve sheath compartment syndrome (ONSCS caused by severely elevated intracranial pressure and fungal loading in the peri-optic space. An improved understanding of these mechanisms and recognition of the important role played by raised intracranial pressure allows for more targeted treatment measures and better outcomes. In the present case series of 90 HIV co-infected patients with cryptococcal meningitis, we present the clinical and electrophysiological manifestations of Cryptococcus-induced visual loss and review the mechanisms involved.

  18. Severe bleeding complications other than intracranial hemorrhage in neonatal alloimmune thrombocytopenia: a case series and review of the literature.

    Science.gov (United States)

    Winkelhorst, Dian; Kamphuis, Marije M; de Kloet, Liselotte C; Zwaginga, Jaap Jan; Oepkes, Dick; Lopriore, Enrico

    2016-05-01

    The most feared bleeding complication in fetal and neonatal alloimmune thrombocytopenia (FNAIT) is an intracranial hemorrhage (ICH). However, FNAIT may also lead to other severe bleeding problems. The aim was to analyze this spectrum and evaluate the occurrence of severe hemorrhages other than ICH in fetuses or neonates with FNAIT. A retrospective chart analysis of cases of FNAIT presenting with severe bleeding complications other than ICH at our institution from 1990 to 2015 was conducted. Additionally, a review of the literature was performed to identify case reports and case series on FNAIT presenting with extracranial hemorrhage. Of 25 fetuses or neonates with severe bleeding due to FNAIT, three had isolated severe internal organ hemorrhage other than ICH, two pulmonary hemorrhages and one gastrointestinal hemorrhage. Two of these three neonates died due to this bleeding. Eighteen cases of extracranial bleeding complications as a first presentation of FNAIT were found in the literature, including ocular, gastrointestinal, spinal cord, pulmonary, renal, subgaleal, and genitourinary hemorrhages. Bleeding complications other than ICH may be more extensive, and the presentation of FNAIT may have a greater spectrum than previously described. A high index of suspicion on the possible diagnosis of FNAIT with any bleeding complication in a fetus or neonate may enable adequate diagnostics, adequate treatment, and appropriate follow-up in future pregnancies, as is especially relevant for FNAIT. © 2016 AABB.

  19. Mesenchymal-to-endothelial transition in Kaposi sarcoma: a histogenetic hypothesis based on a case series and literature review.

    Directory of Open Access Journals (Sweden)

    Simona Gurzu

    Full Text Available OBJECTIVES: Although several studies have been conducted regarding Kaposi sarcoma (KS, its histogenesis still remains to be elucidated. The aim of our study was to analyze the immunophenotype of Kaposi sarcoma and to present a hypothesis about the histogenesis of this tumor, based on a case series and a review of relevant literature. METHODS: In 15 cases of KSs diagnosed during 2000-2011, the clinicopathological features were correlated with the immunoexpression of c-Kit, SMA, CD34, CD31, vascular endothelial growth factor (VEGF, COX-2, c-KIT, smooth muscle antigen (SMA, and stem cell surface marker CD105. RESULTS: Both CD105 and c-KIT rate of the spindle-shaped tumor cell positivity increased in parallel to the pathological stage. All cases displayed CD105 and weak c-KIT positivity in the endothelial cells. SMA, VEGF, and COX-2 were focally expressed in all cases. CD34 marked both endothelium and spindle-shaped tumor cells. No c-KIT expression was noticed in KS of the internal organs. CONCLUSIONS: KS seems to be a variant of myofibroblastic tumors that originates from the viral modified pluripotent mesenchymal cells of the connective tissue transformed in spindle-shaped KS cells, followed by a mesenchymal-endothelial transition and a myofibroblastic-like differentiation. This paper mailnly showed that KS cannot be considered a pure vascular tumor.

  20. Impact of the "salary scholarship" impact profile and student achievement.

    Directory of Open Access Journals (Sweden)

    Berlanga, Vanesa

    2013-08-01

    Full Text Available In Spain, within the framework of the Strategy 2015, the implementation of scholarships, grants and wages especially adapted to the new situation of the European Higher Education, intended to ensure access to university education to those most disadvantaged social groups economically. This research makes an ex post facto, descriptive-comparative aimed at assessing the impact of the grant salary, as an economic factor, on equity, access and academic performance in the first year of college. The study was conducted with a total of 10,394 new students in the 2010-11 cohort at the University of Barcelona, from the database from the institution itself. A total of 642 students agreed to grant salary, with differences depending on the branch of knowledge, gender, and the path to college. In relation to their peers, scholarship students come from families with occupations and / or study less, so scholarships model contributes to equity in access. In relation to performance analysis, scholarship students enrolled and present, on average, a larger number of subjects in order to meet the academic requirements for scholarship renewal, but the results are final academic in several branches knowledge, influenced negatively. One possible explanation is the largest academic pressure of this group in a phase usually complicated: the transition to college.

  1. A Model for Institutional Infrastructure to Support Digital Scholarship

    Directory of Open Access Journals (Sweden)

    Malcolm Wolski

    2014-09-01

    Full Text Available There is a driving imperative for new knowledge, approaches and technologies to empower scholarship, especially in emerging areas of inquiry. Sources of information now extend beyond the written word to include a wide range of born-digital objects. This paper examines the changing landscape in which digital scholars find, collaborate, create and process information and, as a result, scholarship is being transformed. It discusses the key elements required to build an institutional infrastructure, which will not only support new practices but also integrate scholarly literature into emerging and evolving models that generate true digital scholarship. The paper outlines some of the major impediments in implementing such a model, as well as suggestions on how to overcome these barriers.

  2. Oral Health Research and Scholarship in 2040: Executive Summary.

    Science.gov (United States)

    Polverini, Peter J

    2017-09-01

    This executive summary for Section 6 of the "Advancing Dental Education in the 21st Century" project provides an overview of five background articles that address the role of research and scholarship in dental education in the year 2040. Beginning with a historical account of research and discovery science in dentistry's evolution as a profession, the article then reviews the role of early thought leaders and organized dentistry in establishing research as a cornerstone of dental education and dental practice. The dental research workforce faces an uncertain future fueled by a volatile funding environment and inadequate mentoring and training of research faculty. Dental schools must forge stronger academic and scientific ties to their university and academic health centers and will be challenged to develop sustainable research and patient care collaborations with other health professions. The changing health care environment will create new opportunities for oral health care providers to expand their scope of practice and focus on prevention and screening for non-communicable chronic diseases. Dental practitioners in the future are likely to place greater emphasis on managing the overall health of their patients while promoting closer integration with other health professionals. All dental schools must develop a sustainable research mission if they hope to graduate dentists who function effectively in a collaborative health care environment. The changing scientific and health care landscape will dramatically alter dental education and dental practice. Dental schools need to reconsider their research and educational priorities and clinical practice objectives. Until dental schools and the practicing community come to grips with these challenges, a persistent attitude of complacency will likely be at the dental profession's peril.

  3. Creating a Community of Difference in Entrepreneurship Scholarship

    DEFF Research Database (Denmark)

    Gartner, William B.

    2013-01-01

    This article argues for alternative forms of inquiry for exploring aspects of entrepreneurship scholarship that are often unseen, ignored or minimized. The label, ‘The European School of Entrepreneurship’, might serve as a useful rubric for identifying a community of scholars with tendencies...... towards the following: (1) an interest in the history of ideas that inform entrepreneurship scholarship, (2) a willingness to step outside of the entrepreneurship field, itself, to embrace a variety of ideas, particularly from philosophy and the humanities and (3) a concern for the ‘other’, so...

  4. Continuing education modules and the scholarship of engagement.

    Science.gov (United States)

    Mitchell, Jim

    2010-01-01

    Economic and political trends underscore the importance of engaged scholarship as evidence that colleges and universities are serving their constituencies. Set in a background of debate about pure versus applied social science this article describes a planned approach to continuing gerontological education grounded firmly in the principles of the scholarship of engagement. The description includes efforts to ascertain through a two-phase state-wide survey continuing education needs and preferred venue in a segment of the North Carolina aging services workforce. Subsequent surveys were used to define and prioritize modular continuing education topics suitable for web-based delivery.

  5. Effect of the CONACYT scholarship in terminal efficiency

    Directory of Open Access Journals (Sweden)

    Miguel Álvarez Gómez

    2012-05-01

    Full Text Available This article research on the impact of the scholarship for postgraduate studies awarded by CONACYT in terminal efficiency postgraduate in Mexico. Analyzed in the master in technologies for learning in the Center University of the coast of the University of Guadalajara (UdeG. The results show that the studied variables are independent. The study highlighting the fact that there is therefore no effect or relationship on postgraduate scholarship CONACYT, as they are granted at the present time, with students certification and therefore with the terminal efficiency. Suggests some changes in the provision of economic aid to become a more determinant factor.

  6. Long-term refractive changes in children following ptosis surgery: a case series and a review of the literature.

    Science.gov (United States)

    Byard, Stephen D; Sood, Vaneeta; Jones, Carole A

    2014-12-01

    The purpose of the study was to evaluate the long-term changes in refractive error in children with congenital ptosis managed with unilateral levator resection, and to provide a brief literature review and discuss the possible mechanisms for refractive change in the post-operative period. We present a retrospective consecutive case series of children (4-11 years old) who underwent unilateral levator resection, performed by a single ophthalmic surgeon to manage congenital ptosis between 1998 and 2001 at Maidstone Hospital, Kent. Cycloplegic refraction data were obtained prior to surgery and at the last clinic visit post surgery (minimum follow-up 12 months). The refractive changes in the non-operated contralateral eye were used as age-matched controls. Data were analysed for changes in refractive sphere and cylinder. Forty-three patients underwent levator resection during this 3-year period. Complete refraction data were available for 13 patients. The mean age at the time of levator resection was 6.7 years. The refractive error was greater on the side with the ptosis (61 %). At the last clinical follow up (mean 36.3 months; SD 34 months), the mean spherical change in the operated eye was 0.41D (range 0.12-1.50D), compared to a mean change of 0.40D (range 0.25-2.00D) in the non-operated eye. The mean cylindrical change in the operated eyes was 0.38D (range 0.25-1.00D), compared to a mean of 0.21D (range 0.50-1.75D) in the non-operated eye. In conclusion, this study did not show a significant change in refractive error following levator resection surgery for congenital ptosis.

  7. Transient Diabetes Insipidus After Discontinuation of Vasopressin in Neurological Intensive Care Unit Patients: Case Series and Literature Review.

    Science.gov (United States)

    Bohl, Michael A; Forseth, James; Nakaji, Peter

    2017-01-01

    Arginine vasopressin (AVP) is a common second-line or third-line vasopressor used in critically ill neurosurgical patients. Neurosurgical indications include hyperdynamic therapy for vasospasm, maintenance of cerebral perfusion pressure in patients with intracranial hypertension, and prevention of hypotension in patients with sepsis. A series of 6 neurosurgical patients receiving AVP infusions developed severe but transient diabetes insipidus (tDI) after cessation of AVP. To our knowledge, no previous reports of this phenomenon in neurosurgical patients have been published. We reviewed the clinical histories, intensive care unit treatment, medication administration records, and laboratory values of these patients, and we found recurrent elevated serum sodium and urine output and decreased urine specific gravity after discontinuation of AVP. Resolution of tDI occurred upon resumption of AVP or administration of desmopressin. Elevated serum sodium levels were often severe, resulting in worsened clinical outcomes. When AVP was resumed, tDI typically recurred if AVP was again tapered and discontinued. Routine administration of desmopressin was useful in controlling sodium levels until the tDI resolved. Recognition of this phenomenon has caused us to change our clinical management of neurosurgical patients receiving AVP. We hypothesize that tDI is caused by downregulation of the V2 receptor mass in the renal distal convoluted tubule and collecting duct cells. When AVP is discontinued, patients develop nephrogenic tDI secondary to decreased V2 receptor binding, which explains why desmopressin is effective in correcting tDI. Future research includes a large prospective study to determine risk factors for tDI, its incidence, and its pathophysiology. Copyright © 2016 Elsevier Inc. All rights reserved.

  8. Onychomadesis after hand-foot-and-mouth disease outbreak in northern Greece: case series and brief review of the literature.

    Science.gov (United States)

    Apalla, Zoe; Sotiriou, Eleni; Pikou, Olga; Lefaki, Ioanna; Lallas, Aimilios; Lazaridou, Elizabeth; Ioannides, Demetris

    2015-09-01

    Nail abnormalities in childhood are generally uncommon. Recently, onychomadesis was described as a late complication of hand-foot-and-mouth disease (HFMD). Onychomadesis outbreaks following HFMD have been reported in many countries worldwide. To present a case series of onychomadesis in children, following HFMD outbreak in Northern Greece, and review literature data. Children with evident onychomadesis attending the outpatient clinic between November 2012 and January 2013 were included in the study. A questionnaire including demographic personal and family history information of the children was completed by the parents. Patients were clinically examined, and their pediatric and dermatological records were studied to confirm precedent HFMD. Direct microscopic examination and cultures for fungi were performed. Exposure of participants to coxsackievirus, based on serology testing during infection, was also recorded. Sixty-eight children with onychomadesis were included. The mean number of affected nails was 8.82. Fingernails were more often involved. Previous clinical diagnosis of HFMD was confirmed in 67/68 cases. The mean time from HFMD diagnosis to onychomadesis development was 39.6 days (range: 28-56 days, STD: 7.33). Direct microscopic examination, as well as cultures for fungal species, was negative for the whole sample size. All the nail changes were transient with spontaneous regrowth after 1-4 months. Our data indicate that onychomadesis outbreak in the region of Thessaloniki during fall-winter 2012-13 was highly related to the outbreak of HFMD. Our study reinforces existing evidence for the association between onychomadesis and HFMD. © 2015 The International Society of Dermatology.

  9. Orthognathic Surgery in Patients With Congenital Myopathies and Congenital Muscular Dystrophies: Case Series and Review of the Literature.

    Science.gov (United States)

    Bezak, Brett J; Arce, Kevin A; Jacob, Adam; Van Ess, James

    2016-03-01

    This case series examined preoperative findings and the surgical, anesthetic, and postoperative management of 6 patients with congenital myopathies (CMs) and congenital muscular dystrophies (CMDs) treated at a tertiary medical institution with orthognathic surgery over 15 years to describe pertinent considerations for performing orthognathic surgery in these complex patients. According to the institutional review board-approved protocol, chart records were reviewed for all orthognathic surgical patients with a clinical, genetic, or muscle biopsy-proved diagnosis of CM or CMD. Six patients (5 male, 1 female) qualified, and they were treated by 4 surgeons in the division of oral and maxillofacial surgery from 1992 through 2007. Average age was 19.5 years at the time of orthognathic surgery. Five patients had Class III malocclusions and 1 patient had Class II malocclusion. All 6 patients had apertognathia with lip incompetence. Nasoendotracheal intubation with a difficulty of 0/3 (0=easiest, 3=most difficult) was performed in all cases. Routine induction and maintenance anesthetics, including halogenated agents and nondepolarizing muscle relaxants, were administered without malignant hyperthermia. All 6 patients underwent Le Fort level osteotomies; 4 also had mandibular setback surgery with or without balancing mandibular inferior border osteotomies. Five patients required planned intensive care unit care postoperatively (average, 18.4 days; range, 4 to 65 days). Postoperative respiratory complications resulting in major blood oxygen desaturations occurred in 5 patients; 4 of these patients required reintubation during emergency code response. Five patients required extended postoperative intubation (average, 4.2 days; range, 3 to 6 days) and ventilatory support. Average hospital length of stay was 21.8 days (range, 6 to 75 days). Average postoperative follow-up interval was 29.8 weeks (range, 6 to 128 weeks). Patients with CMs or CMDs often have characteristic

  10. Authors@UF Campus Conversation Series: A Case Study

    Science.gov (United States)

    Silver, Isabel

    2014-01-01

    The Authors@UF program series emerged to showcase the scholarship and creativity of faculty, creating an intellectual forum within the academic library, and providing informal, extra-curriculum, academic engagement between students and faculty outside the classroom. This article identifies steps to launch an author program, and considerations in…

  11. Motivated by Money: Students with Academic Scholarships versus Those without and Their Emotional Intelligence

    Science.gov (United States)

    Giroir, Elizabeth Marie Elbert

    2009-01-01

    The purpose of this study was to determine the retention rate of students who had received academic scholarships versus students who had not received academic scholarships but met the qualifications to receive the scholarships and the effects of emotional intelligence on these students. The data collection mechanisms for this study included the…

  12. 34 CFR 654.30 - How does a student apply to an SEA for a scholarship?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does a student apply to an SEA for a scholarship...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM How Does a Student Apply to an SEA for a Scholarship? § 654.30 How does a student apply to an SEA for a...

  13. 34 CFR 663.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 663.22 Section 663.22 Education Regulations of the Offices of the Department of... Scholarship Board select fellows? The J. William Fulbright Foreign Scholarship Board selects fellows on the...

  14. In the Spirit of William Georgetti: Scrutiny of a Prestigious National Scholarship Selection Process

    Science.gov (United States)

    Schluter, Philip J.; Johnston, Lucy

    2017-01-01

    Postgraduate scholarship programmes are increasingly important for supporting gifted students from diverse backgrounds. Systems and processes in the application, determination and delivery of scholarships must be robust, transparent, accountable and equitable. However, they are rarely evaluated. One of the most prestigious scholarships in New…

  15. 42 CFR 1001.1501 - Default of health education loan or scholarship obligations.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Default of health education loan or scholarship... Permissive Exclusions § 1001.1501 Default of health education loan or scholarship obligations. (a... individual that the Public Health Service (PHS) determines is in default on repayments of scholarship...

  16. 77 FR 75918 - VA Health Professional Scholarship and Visual Impairment and Orientation and Mobility...

    Science.gov (United States)

    2012-12-26

    ... AFFAIRS 38 CFR Part 17 RIN 2900-AO34 VA Health Professional Scholarship and Visual Impairment and Orientation and Mobility Professional Scholarship Programs AGENCY: Department of Veterans Affairs. ACTION... Professional Scholarship Program (HPSP) regulations. VA also proposes to establish regulations for a new...

  17. 42 CFR 62.11 - When can a scholarship program payment obligation be discharged in bankruptcy?

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false When can a scholarship program payment obligation... HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL HEALTH SERVICE CORPS SCHOLARSHIP AND LOAN REPAYMENT PROGRAMS National Health Service Corps Scholarship Program § 62.11 When can a...

  18. Multiple Perspectives: Whither Scholarship in the Work of Enhancing the Quality of Teaching and Learning?

    Science.gov (United States)

    Dangel, Julie Rainer

    2011-01-01

    Whither Scholarship in the Work of Enhancing the Quality of Teaching and Learning? This is an important query because it acknowledges, embraces, questions, and challenges the role of scholarship in enhancing teaching and learning. Interestingly, these four verbs help the author categorize her perspectives on the use of scholarship. Drawing from…

  19. To Lift the Leaden-Eyed: The Historical Roots of Ernest L. Boyer's "Scholarship Reconsidered"

    Science.gov (United States)

    Moser, Drew

    2014-01-01

    This article focuses on the historical roots of Ernest Boyer's most popular work, "Scholarship Reconsidered: Priorities of the Professoriate" (1990). Seeking to transcend the traditional view of scholarship as simply that which is published, Boyer expanded scholarship to include four domains: discovery, application, integration, and…

  20. A Holistic Model of Engaged Scholarship: Telling the Story across Higher Education's Missions

    Science.gov (United States)

    Franz, Nancy

    2016-01-01

    Faculty and administrators still struggle to practice and support a holistic approach to engaged scholarship. Many institutions have created a culture of engaged scholarship, yet faculty are looking for practical ways to plan, implement, and reflect on engaged scholarship due to productivity expectations. New faculty are often drawn to the idea of…

  1. 42 CFR 62.6 - How will individuals be selected to participate in the scholarship program?

    Science.gov (United States)

    2010-10-01

    ... the scholarship program? 62.6 Section 62.6 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL HEALTH SERVICE CORPS SCHOLARSHIP AND LOAN REPAYMENT PROGRAMS National Health Service Corps Scholarship Program § 62.6 How will individuals...

  2. Social Scholarship: Reconsidering Scholarly Practices in the Age of Social Media

    Science.gov (United States)

    Greenhow, Christine; Gleason, Benjamin

    2014-01-01

    This conceptual exploration inquires, what is scholarship reconsidered in the age of social media? How ought we to conceptualize "social scholarship"--a new set of practices being discussed in various disciplines? The paper offers a critical examination of the practical and policy implications of reconsidering scholarship in light of…

  3. 34 CFR 654.1 - What is the Robert C. Byrd Honors Scholarship Program?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What is the Robert C. Byrd Honors Scholarship Program...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION ROBERT C. BYRD HONORS SCHOLARSHIP PROGRAM General § 654.1 What is the Robert C. Byrd Honors Scholarship Program? Under the Robert C. Byrd Honors...

  4. 34 CFR 611.52 - What are a grantee's programmatic responsibilities for ensuring that scholarship recipients...

    Science.gov (United States)

    2010-07-01

    ... ensuring that scholarship recipients become successful teachers in high-need schools? 611.52 Section 611.52... EDUCATION, DEPARTMENT OF EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.52 What are a grantee's programmatic responsibilities for ensuring that scholarship recipients become successful...

  5. 26 CFR 1.117-1 - Exclusion of amounts received as a scholarship or fellowship grant.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Exclusion of amounts received as a scholarship... from Gross Income § 1.117-1 Exclusion of amounts received as a scholarship or fellowship grant. (a) In general. Any amount received by an individual as a scholarship at an educational institution or as a...

  6. 78 FR 51067 - VA Health Professional Scholarship and Visual Impairment and Orientation and Mobility...

    Science.gov (United States)

    2013-08-20

    ... AFFAIRS 38 CFR Part 17 RIN 2900-AO34 VA Health Professional Scholarship and Visual Impairment and Orientation and Mobility Professional Scholarship Programs AGENCY: Department of Veterans Affairs. ACTION... Scholarship Program (HPSP) regulations. VA is also establishing regulations for a new program, the Visual...

  7. 34 CFR 662.22 - How does the J. William Fulbright Foreign Scholarship Board select fellows?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does the J. William Fulbright Foreign Scholarship Board select fellows? 662.22 Section 662.22 Education Regulations of the Offices of the Department of... Foreign Scholarship Board select fellows? (a) The J. William Fulbright Foreign Scholarship Board selects...

  8. Sketching the Contours of the Scholarship of Teaching and Learning in Theology and Religion

    Science.gov (United States)

    Killen, Patricia O'Connell; Gallagher, Eugene V.

    2013-01-01

    This article argues that there is an identifiable scholarship of teaching and learning in theology and religion that, though varied in its entry points and forms, exhibits standards of excellence recognizable in other forms of scholarship. Engaging in this scholarship enhances a professor's possession of practice and often reveals insights into…

  9. Growing a Scholarship of Teaching and Learning Institutionally

    Science.gov (United States)

    Vithal, Renuka

    2018-01-01

    While a number of studies report on how a scholarship of teaching and learning (SoTL) has been implemented in particular disciplines or faculties, arguably much less is known about how this can be achieved university-wide. This paper brings the lens of SoTL retrospectively, from the vantage position of a university leader, to a range of teaching…

  10. Wikipedia as Public Scholarship: Communicating Our Impact Online

    Science.gov (United States)

    Rush, Elizabeth K.; Tracy, Sarah J.

    2010-01-01

    To contribute to the forum asking "Has Communication Research Made a Difference?," this essay examines whether communication scholarship makes a difference (a) to those who search for information online, (b) in the sense that a primary way our research can make a difference is through its accessibility, and (c) by using the criteria of its…

  11. EU Foreign Relations Law as a Field of Scholarship

    NARCIS (Netherlands)

    Larik, J.E.

    2017-01-01

    EU external relations law is a doubly peculiar field of scholarship that has attracted significant scholarly attention over the last several decades. It is both part of EU law—considered a "new legal order" distinct from international law—and it is concerned with the European Union as a global

  12. Post-Modern Scholarship: Contributions from a Practice Profession.

    Science.gov (United States)

    Stock, Patricia Lambert

    1996-01-01

    Demonstrates how the work published in "English Education" between 1994 and 1996 figures within the larger body of what has come to be called post-modern scholarship. Defines postmodernism and then considers how the work published in "English Education" contributes to postmodern thought and to the study and teaching of…

  13. Documenting Gratitude as a Practice in Positive Scholarship

    Science.gov (United States)

    Franks, Tara M.

    2015-01-01

    As an emerging interest area, positive communication scholarship focuses on issues of happiness and well-being in a variety of social contexts. Borrowing from positive psychology and happiness literature (Lyubomirsky, 2008), positive communication research explores expressions of gratitude, kindness, compassion, and forgiveness, as well as issues…

  14. Using Postcolonial Scholarship to Address Equity in Transnational Higher Education

    Science.gov (United States)

    Sidhu, Ravinder

    2015-01-01

    This article uses postcolonial scholarship to understand the knowledge and cultural politics that underpin Australian-provided transnational higher education (TNHE) programmes in Singapore and Malaysia. A case is made for TNHE practices to develop an "engaged pedagogy" and "ethics of care" as it relates to transnational…

  15. Investigatory Trends in Emerging Facebook Research: Implications for Communication Scholarship

    Science.gov (United States)

    Fenner, Christopher J.; Pitrowski, Chris

    2017-01-01

    Since the advent of Facebook, researchers across academic disciplines have examined the nature and scope of scholarship regarding this SNS. Based on a content analysis approach, Piotrowski (2012) reported that many popular issues in the media on the topic of Facebook are largely ignored by research investigators. Due to the proliferation of…

  16. Scholarships bring hope to poor Palestinian women | IDRC ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2010-10-22

    Oct 22, 2010 ... It has attracted funding also from the Canadian International Development Agency, the OPEC Fund for International Development, Qatar, the United States, France, and Spain. The United Nations Relief and Works Agency for Palestine Refugees in the Near East administers the program. The scholarship ...

  17. Merit Scholarships Are No Quick Fix for College Quality.

    Science.gov (United States)

    Kealy, Mary Jo; Rockel, Mark L.

    1988-01-01

    Presents a method allowing college leaders to assess the potential success of an academic merit scholarship program. Specifies a college choice model accounting for the price/quality trade-off, using Colgate University as an example. Quality differences between schools in an individual's choice set are the most important determinants of college…

  18. Scholarship Fund for Palestinian Refugee Women in Lebanon

    International Development Research Centre (IDRC) Digital Library (Canada)

    miellina

    As 'Gavel' of the Refugee Working Group (RWG),. Canada has engaged in activities meant to produce tangible benefits for Palestinian refugees without prejudice to their rights and future status. A. Canadian-led International Mission to Refugee. Camps in Lebanon in 1997 noted the desirability of enhanced scholarship ...

  19. Success of a scholarship scheme for rural students | Ross | South ...

    African Journals Online (AJOL)

    Background. Mosvold Hospital is one of 5 district hospitals providing care for 555 000 indigent people in the Umkhanyakude district, northern KwaZulu-Natal. Recruitment of professional staff is an ongoing challenge for hospital management. An innovative, locally based scholarship scheme, the Friends of Mosveld ...

  20. AAFCS Resources for Elevating Research and Scholarship in FCS

    Science.gov (United States)

    Myers, Lori A.

    2017-01-01

    Elevating research and supporting scholarship are both a responsibility and core value of all family and consumer sciences (FCS) professionals. This responsibility may involve: (1) Introducing the research process under graduate students; (2) Guiding the research of graduate students; (3) Mentoring a junior faculty member to establish a research…

  1. Models and Exemplars of Scholarship in the Teaching of Psychology

    Science.gov (United States)

    Buskist, William; Carlson, Janet F.; Christopher, Andrew N.; Prieto, Loreto; Smith, Randolph A.

    2008-01-01

    This article provides ideas for engaging in the scholarship of teaching in psychology. Topics covered include contributing to the Society for the Teaching of Psychology's Office of Teaching Resources in Psychology and "Teaching of Psychology". Writing and editing books also constitute scholarly work. Finally, teaching with intentionality…

  2. The Trajectory of Scholarship about Self-Regulated Learning

    Science.gov (United States)

    Winne, Philip H.

    2017-01-01

    The trajectory of scholarship about self-regulated learning (SRL) originates in mid-19th-century writings about learners' sense of responsibility in self education. Although Descartes's 17th-century writings implied mental activities consistent with metacognition, a central feature of SRL, these were inarticulate until Flavell and colleagues'…

  3. Learning Theories 101: Application to Everyday Teaching and Scholarship

    Science.gov (United States)

    Kay, Denise; Kibble, Jonathan

    2016-01-01

    Shifts in educational research, in how scholarship in higher education is defined, and in how funding is appropriated suggest that educators within basic science fields can benefit from increased understanding of learning theory and how it applies to classroom practice. This article uses a mock curriculum design scenario as a framework for the…

  4. Expanding Access and Opportunity: The Washington State Achievers Scholarship

    Science.gov (United States)

    O'Brien, Colleen

    2011-01-01

    In 2001, the Bill & Melinda Gates Foundation launched the multi-year, multi-million dollar Washington State Achievers Scholarship program. Concerned about disparities in college participation for low-income students in the state of Washington versus their wealthier peers, the Gates Foundation partnered with the College Success Foundation…

  5. Breaking down the walls: thoughts on the scholarship of integration.

    Science.gov (United States)

    Dauphinée, D; Martin, J B

    2000-09-01

    The scholarship of integration is concerned with making connections across scientific disciplines, placing the work of individual investigators and their specialty fields into a larger context, and educating nonspecialists. The authors focus their comments on the biomedical sciences, but observe that closer integration of the biomedical and behavioral sciences will be particularly crucial to advance understanding of the human brain. They observe that as biomedical sciences become more technologically sophisticated, progress is increasingly dependent on sciences such as physics, chemistry, engineering, and related fields. However, the scholarship of integration has been slower than other forms of scholarship to gain acceptance as an integral activity of the professoriate. The isolation of disciplines from one another, particularly at large universities, and the perception of interdisciplinary work as risky and professionally unrewarding are among the forces that may discourage integrative scholarship. In addition, a troubling disconnect exists between the scientific community and the larger public in the understanding of science. Leaders in academic medicine and science must develop strategies to move interdisciplinary work from the margins into the mainstream of academia. Solutions that have been proposed include creating new research entities and funding mechanisms dedicated to interdisciplinary work; reinvigorating the integrative role of the physician-scientist; and training specialists in translational research. The scientific community must also work to develop more effective means of communicating the importance of its work to the public.

  6. Promotion and the Scholarship of Teaching and Learning

    Science.gov (United States)

    Vardi, Iris; Quin, Robyn

    2011-01-01

    The move toward recognizing teaching academics has resulted in the Scholarship of Teaching and Learning (SoTL) gaining a greater prominence within the academy, particularly through the academic promotions system. With several Australian universities now providing opportunities for teaching staff who do not engage in research to be promoted, it is…

  7. Graduate Student Development through the Scholarship of Teaching and Learning

    Science.gov (United States)

    Schram, Laura N.; Allendoerfer, Michelle G.

    2012-01-01

    The scholarship of teaching and learning (SoTL) can be a valuable tool in preparing graduate students as future faculty. Yet, graduate students are often warned that the academic job market does not value SoTL research. We present results of a survey of current and former graduate students who conducted SoTL research. Respondents overwhelmingly…

  8. Fraud, Ethics, and the Disciplinary Contexts of Science and Scholarship.

    Science.gov (United States)

    Fox, Mary Frank

    1990-01-01

    Posits the disciplinary context is the locus of legitimate and illegitimate activity in science and scholarship. Compares structural features of sciences and social sciences that influence malpractice rates, type, and detection. These features include research activity, replication and replicability, coauthorship, plagiarism, locus of creativity…

  9. Undergraduate Learning through Engaged Scholarship and University-Community Partnerships

    Science.gov (United States)

    Tarantino, Kristen L.

    2017-01-01

    The impact of university-community partnerships and involvement in engaged scholarship on student learning was examined through in-depth interviews with undergraduate members of a student-led, community-based research organization at a selective mid-Atlantic university. Students reported benefits of participation that included increasing critical…

  10. A New Scholarship of Classroom-based, Open, Communal Inquiry

    Directory of Open Access Journals (Sweden)

    Jan Parker

    2013-03-01

    community interest groups (through scholarship of application projects, grounding and re-valuing the research agenda of higher institutes and professions while reimaging the curriculum, will prepare the student to become that lifelong, practitioner-scholar so needed for our future.

  11. Rewarding Community-Engaged Scholarship: A State University System Approach

    Science.gov (United States)

    Saltmarsh, John; Wooding, John

    2016-01-01

    The need for new and revised structures to reward new forms of scholarship is being examined nationally and globally. It is also being examined on campuses that make up the University of Massachusetts system, all which are classified by the Carnegie Foundation for Community Engagement. This paper reports on the collective exploration by the five…

  12. The "New" Scholarship: Implications for Engagement and Extension

    Science.gov (United States)

    Fear, Frank A.; Sandmann, Lorilee R.

    2016-01-01

    The engagement movement in higher education is related to the groundbreaking work of the late Ernest Boyer. The magnitude of Boyer's contribution is considerable, reflected certainly in the words of the late Donald Schön--a prolific contributor in his own right--when he interpreted Boyer's proposals as "the new scholarship." Despite his…

  13. Scholarship in nursing: Degree-prepared nurses versus diploma ...

    African Journals Online (AJOL)

    Background: The nursing profession needs nurses with a higher level of education and not merely more nurses to enhance patient outcomes. To improve quality patient care the nursing discipline needs to be advanced through theory development and knowledge generation, thus graduate nurses. Nursing scholarship ...

  14. Scholarships for Pursuing-Post Graduate Studies in Mathematics

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 5; Issue 8. Scholarships for Pursuing - Post Graduate Studies in Mathematics. Information and Announcements Volume 5 Issue 8 August 2000 pp 103-104. Fulltext. Click here to view fulltext PDF. Permanent link:

  15. Building framework for nursing scholarship: guidelines for appointment and promotion.

    Science.gov (United States)

    Honig, Judy; Smolowitz, Janice; Larson, Elaine

    2013-01-01

    As nursing academia responds to shifts in nursing education--the emergence of clinically focused doctoral degrees and an emphasis on evidence-based practice, comparative effectiveness, and translational research, nursing scholarship is undergoing transformation. This article outlines guidelines for appointment and promotion that incorporate the academic tripartite and are relevant for all faculty. A clear and equitable pathway for professorial advancement for the both the clinician and research faculty is delineated. Without such clarity and equity, the unique contributions of clinical and research scholars and the synergy that results from these distinctions will not be garnered. Although there is significant overlap in the criteria, there are also distinguishing scholarly activities and outcomes. For each standard at each rank, unique sample criteria of clinical and research scholarship are outlined and the shared scholarly activities that demonstrate the standard. Using an adaptation of Boyer's model, the guidelines incorporate a broadened view of nursing scholarship and offer a framework for nursing academia that recognizes new ways of knowledge. Although recognizing the coexistence of science and practice, these guidelines offer a clear trajectory for advancement in the professorial role that applies an expanded perspective of and provide a framework for nursing scholarship. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. The Ideal of African Scholarship and its Implications for Introductory ...

    African Journals Online (AJOL)

    Thinking of an academic discipline in terms of a 'social practice' (MacIntyre) helps in formulating what the ideal captured in the slogan 'African scholarship' can contribute to the discipline. For every practice is threatened by the attractiveness of goods external to the practice – in particular, competitiveness for its own sake ...

  17. Need for Gender Neutrality in Cartooning Scholarship | Otu ...

    African Journals Online (AJOL)

    The person of a woman seems to continue to mean inability, weakness and perhaps, inexistence in especially the field of cartooning. Hypothetically, the cartooning scholarship basically presents cartooning studies with a mere mention of the female cartoonist in a ratio of about 1 to 80 studies done. This article presents a ...

  18. School Group Performance in the Commonwealth Secondary Scholarship Examination

    Science.gov (United States)

    Sumner, R. J.; Broadhurst, N. A.

    1973-01-01

    Reports the results of a survey based on the Commonwealth Secondary Scholarship Examination (C.S.S.E.). Freshman students at Flinders University (South Australia) were sampled, and results indicated that students from non-government schools performed better, and hence were more able, than those who came from government schools. (JR)

  19. Mesotext. Digitised Emblems, Modelled Annotations and Humanities Scholarship

    NARCIS (Netherlands)

    Boot, P.

    2009-01-01

    Mesotext is a contribution to the debate about the use of digital texts in the humanities. It discusses the creation of digital editions and the ways digital editions can be made productive in humanities scholarship. The special case it considers is that of research into the emblem, the sixteenth

  20. Bridging the Mass-Interpersonal Divide: Synthesis Scholarship in "HCR."

    Science.gov (United States)

    O'Sullivan, Patrick B.

    1999-01-01

    Notes that the history of the communication field has been marked by theoretical fragmentation, identity crises, and disciplinary isolation. Assesses this journal's contribution to synthesis scholarship and compares it to similar efforts in other national journals. Examines how new communication technologies are intensifying the need for scholars…

  1. Finding the Motivation: The Evolution of a Faculty Scholarship Symposium

    Science.gov (United States)

    Pifer, Meghan J.; Reisboard, Dana; Staulters, Mimi; Li, Xiaobao; Gozza-Cohen, Mary; McHenry, Nadine; Schaming, Susan; Gilio, Brenda

    2014-01-01

    This article describes the evolution of a faculty scholarship symposium within the school of education at a regional comprehensive university. The article outlines the initial structure and goals of the symposium as well as the development of the model over time. The influence of leadership, culture, and individual goals and backgrounds are…

  2. Fourier series

    CERN Document Server

    Tolstov, Georgi P

    1962-01-01

    Richard A. Silverman's series of translations of outstanding Russian textbooks and monographs is well-known to people in the fields of mathematics, physics, and engineering. The present book is another excellent text from this series, a valuable addition to the English-language literature on Fourier series.This edition is organized into nine well-defined chapters: Trigonometric Fourier Series, Orthogonal Systems, Convergence of Trigonometric Fourier Series, Trigonometric Series with Decreasing Coefficients, Operations on Fourier Series, Summation of Trigonometric Fourier Series, Double Fourie

  3. Academic Staff's Views About International Scholarships and Support Programs

    Directory of Open Access Journals (Sweden)

    M. Ertaç ATİLA

    2015-04-01

    Full Text Available The aim of this study is to determine views of academic staff who have been to the United States in order to do a research study by means of scholarships and support programs provided by the Higher Education Council or Scientific or Technological Research Council of Turkey about the scholarship programs. The qualitative study is carried out as a holistic multiple case study research design. The data were gathered through semi-structured interviews from 10 academic staff who participated the scholarship program. Data were analyzed with content analysis technique. The results indicated that application process, time and financial resources were important for the preferences of academic staff in scholarship and support programs. The main reasons for applying the scholar program to undertake an international research study are grouped under three headings as academic, socio-cultural and foreign language improvements. The main influencing factors behind the researchers' preferences to go the United States are its' level of advancements in scientific research and peer influence. Concerning the duration of a research study in abroad the participants thought that 6 months to one year is adequate time and this time depends on the foreign language skills of the researchers, the field of study, subject and project. The main drawbacks of an international research study visit are the long waiting times for having the United States visa with no adequate support, the cost of health insurance and visa, lack of speaking foreign language skills, and adaptation time in the first arrival. As a result, the experienced participants suggested that the future scholarships have to cover health insurance; the researchers have to be supported for developing their foreign language skills and develop a clear research agenda and project prior to going abroad.

  4. DMPD: Translational mini-review series on Toll-like receptors: networks regulated byToll-like receptors mediate innate and adaptive immunity. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available e receptors: networks regulated byToll-like receptors mediate innate and adaptive...ed byToll-like receptors mediate innate and adaptive immunity. Authors Parker LC, Prince LR, Sabroe I. Publi...d byToll-like receptors mediate innate and adaptive immunity. Parker LC, Prince LR, Sabroe I. Clin Exp Immun...17223959 Translational mini-review series on Toll-like receptors: networks regulate

  5. Failure of the inflatable penile prosthesis due to abnormal folding of a low-profile reservoir – A selected case from an overall series and systematic review

    Directory of Open Access Journals (Sweden)

    Roberto Alejandro Navarrete

    2017-09-01

    Full Text Available We present a case from a running series of inflatable penile prosthesis failure due to improper folding of the Conceal™ reservoir. The Conceal™ Low-Profile reservoir gained popularity due to claims of improved cosmesis and ease of implantation. As the number of patients receiving this and other low-profile reservoirs increases, it is imperative to review and document any novel complications. While the Conceal™ reservoir may be preferred in ectopic placement, it may be more prone to fluid lockout facilitated by conformational change. Our review did not identify prior reports of improper folding, which we believe is unique to these low-profile reservoirs.

  6. The Experience of Receiving and Then Losing a Scholarship: A Tracer Study of Secondary School Scholarship Recipients in Uganda

    Science.gov (United States)

    Watson, Cathy; Chapman, David W.; Okurut, Charles Opolot

    2014-01-01

    This study reports findings of a tracer that investigated differences in the profile and subsequent experiences of scholarship recipients in Uganda who were able to complete the lower secondary school cycle (O level) without interruption (N = 174) and those that dropped out before completing their O-level cycle (N = 51), thereby losing their…

  7. Heterogeneity in application, design, and analysis characteristics was found for controlled before-after and interrupted time series studies included in Cochrane reviews.

    Science.gov (United States)

    Polus, Stephanie; Pieper, Dawid; Burns, Jacob; Fretheim, Atle; Ramsay, Craig; Higgins, Julian P T; Mathes, Tim; Pfadenhauer, Lisa M; Rehfuess, Eva A

    2017-11-01

    The aim of the study was to examine the application, design, and analysis characteristics of controlled before-after (CBA) and interrupted time series (ITS) studies and their use in Cochrane reviews. We searched the Cochrane library for reviews including these study designs from May 2012 to March 2015 and purposively selected, where available, two reviews each across 10 prespecified intervention types. We randomly selected two CBA and two ITS studies from each review. Two researchers independently extracted information from the studies and the respective reviews. Sixty-nine reviews considered CBA and ITS studies for inclusion. We analyzed 21 CBA and 16 ITS studies from 11 to 8 reviews, respectively. Cochrane reviews inconsistently defined and labeled CBA and ITS studies. Many studies did not meet the Cochrane definition or the minimum criteria provided by Cochrane Effective Practice and Organisation of Care. The studies present a heterogeneous set of study features and applied a large variety of analyses. While CBA and ITS studies represent important study designs to evaluate the effects of interventions, especially on a population or organizational level, unclear study design features challenge unequivocal classification and appropriate use. We discuss options for more specific definitions and explicit criteria for CBA and ITS studies. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. Considering Teaching Excellence in Higher Education: 2007-2013. A Literature Review since the CHERI Report 2007. HEA Research Series

    Science.gov (United States)

    Gunn, Vicky; Fisk, Anna

    2014-01-01

    This research review explores both the research and the grey literature on university teaching excellence with a specific remit to update an earlier review, "Excellence in Teaching and Learning: a review of literature for the Higher Education Academy". Little, B., et al (2007) The two main aims are: (1) to suggest further areas of…

  9. Impact Factor: Early Career Research & Digital Scholarship

    Science.gov (United States)

    Pasquini, Laura A.; Wakefield, Jenny S.; Roman, Tiffany

    2014-01-01

    It is becoming increasingly vital to publish and share research as well as get citations for the purpose of researcher visibility. The publishing options available for research distribution seem endless. It really is an academic jungle out there! This article reviews why early career researchers and graduate scholars should consider their research…

  10. New Feminist Scholarship: A Guide to Bibliographies.

    Science.gov (United States)

    Williamson, Jane

    This partially annotated bibliography lists 391 bibliographies, resource lists, and literature reviews on women. The entries, published in the late 1960s and throughout the 1970s, are classified alphabetically by author into 30 categories including a general category, anthropology and sociology, art and music, child care, criminal justice,…

  11. Mapping Gender and Migration in Sociological Scholarship: Is It Segregation or Integration?

    Science.gov (United States)

    Curran, Sara R; Shafer, Steven; Donato, Katharine M; Garip, Filiz

    2006-02-01

    A review of the sociological research about gender and migration shows the substantial ways in which gender fundamentally organizes the social relations and structures influencing the causes and consequences of migration. Yet, although a significant sociological research has emerged on gender and migration in the last three decades, studies are not evenly distributed across the discipline. In this article, we map the recent intellectual history of gender and migration in the field of sociology and then systematically assess the extent to which studies on engendering migration have appeared in four widely read journals of sociology (American Journal of Sociology, American Sociological Review, Demography, and Social Forces ). We follow with a discussion of these studies, and in our conclusions, we consider how future gender and migration scholarship in sociology might evolve more equitably.

  12. 34 CFR 611.42 - How does the Secretary calculate the period of the scholarship recipient's service obligation?

    Science.gov (United States)

    2010-07-01

    ... scholarship recipient's service obligation? 611.42 Section 611.42 Education Regulations of the Offices of the... QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.42 How does the Secretary calculate the period of the scholarship recipient's service obligation? (a) Calculation of period of scholarship assistance...

  13. 42 CFR 62.1 - What is the scope and purpose of the National Health Service Corps scholarship program?

    Science.gov (United States)

    2010-10-01

    ... Health Service Corps scholarship program? 62.1 Section 62.1 Public Health PUBLIC HEALTH SERVICE... SCHOLARSHIP AND LOAN REPAYMENT PROGRAMS National Health Service Corps Scholarship Program § 62.1 What is the scope and purpose of the National Health Service Corps scholarship program? These regulations apply to...

  14. 34 CFR 611.47 - What are a scholarship recipient's reporting responsibilities upon the close of the LEA's...

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false What are a scholarship recipient's reporting... EDUCATION TEACHER QUALITY ENHANCEMENT GRANTS PROGRAM Scholarships § 611.47 What are a scholarship recipient...'s academic year, a scholarship recipient whose LEA reports under § 611.46(a) that he or she is...

  15. 34 CFR 611.51 - How does a grantee ensure that a scholarship recipient understands the terms and conditions of...

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false How does a grantee ensure that a scholarship recipient understands the terms and conditions of the scholarship before the recipient leaves the teacher preparation... PROGRAM Scholarships § 611.51 How does a grantee ensure that a scholarship recipient understands the terms...

  16. 42 CFR 62.4 - To whom will scholarship program awards be available in addition to those individuals pursuing...

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false To whom will scholarship program awards be... HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING NATIONAL HEALTH SERVICE CORPS SCHOLARSHIP AND LOAN REPAYMENT PROGRAMS National Health Service Corps Scholarship Program § 62.4 To whom will scholarship program...

  17. A writer's guide to education scholarship: Quantitative methodologies for medical education research (part 1).

    Science.gov (United States)

    Thoma, Brent; Camorlinga, Paola; Chan, Teresa M; Hall, Andrew Koch; Murnaghan, Aleisha; Sherbino, Jonathan

    2018-01-01

    Quantitative research is one of the many research methods used to help educators advance their understanding of questions in medical education. However, little research has been done on how to succeed in publishing in this area. We conducted a scoping review to identify key recommendations and reporting guidelines for quantitative educational research and scholarship. Medline, ERIC, and Google Scholar were searched for English-language articles published between 2006 and January 2016 using the search terms, "research design," "quantitative," "quantitative methods," and "medical education." A hand search was completed for additional references during the full-text review. Titles/abstracts were reviewed by two authors (BT, PC) and included if they focused on quantitative research in medical education and outlined reporting guidelines, or provided recommendations on conducting quantitative research. One hundred articles were reviewed in parallel with the first 30 used for calibration and the subsequent 70 to calculate Cohen's kappa coefficient. Two reviewers (BT, PC) conducted a full text review and extracted recommendations and reporting guidelines. A simple thematic analysis summarized the extracted recommendations. Sixty-one articles were reviewed in full, and 157 recommendations were extracted. The thematic analysis identified 86 items, 14 categories, and 3 themes. Fourteen quality evaluation tools and reporting guidelines were found. Discussion This paper provides guidance for junior researchers in the form of key quality markers and reporting guidelines. We hope that quantitative researchers in medical education will be informed by the results and that further work will be done to refine the list of recommendations.

  18. How we developed the GIM clinician-educator mentoring and scholarship program to assist faculty with promotion and scholarly work.

    Science.gov (United States)

    Bertram, Amanda; Yeh, Hsin Chieh; Bass, Eric B; Brancati, Frederick; Levine, David; Cofrancesco, Joseph

    2015-02-01

    Clinician Educators' (CEs) focus on patient care and teaching, yet many academic institutions require dissemination of scholarly work for advancement. This can be difficult for CEs. Our division developed the Clinician-Educator Mentoring and Scholarship Program (CEMSP) in an effort to assist CEs with scholarship, national reputation, recognition, promotion and job satisfaction. The key components are salary-supported director and co-director who coordinate the program and serve as overall mentors and link CEs and senior faculty, and a full-time Senior Research Coordinator to assist with all aspects of scholarship, a close relationship with the General Internal Medicine (GIM) Methods Core provides advanced statistical support. Funding for the program comes from GIM divisional resources. Perceived value was evaluated by assessing the number of manuscripts published, survey of faculty regarding usage and opinion of CEMSP, and a review of faculty promotions. Although impossible to attribute the contributions of an individual component, a program specifically aimed at helping GIM CE faculty publish scholarly projects, increase participation in national organizations and focus on career progression can have a positive impact.

  19. Digital storytelling: New opportunities for humanities scholarship and pedagogy

    Directory of Open Access Journals (Sweden)

    John F. Barber

    2016-12-01

    Full Text Available At first thought, combining storytelling, digital tools, and humanities seems improbable. For example, digital storytelling is characterized by interactivity, nonlinearity, flexible outcomes, user participation, even co-creation. Such affordances may be disruptive to traditional humanities scholars accustomed to working alone, with physical objects, and following established theoretical guidelines. However, they may be quite appealing to those seeking new opportunities for cross-disciplinary, iterative approaches to practice-based humanities scholarship and pedagogy. This essay defines digital storytelling as a combination of storytelling techniques, digital affordances, and humanities foci, describes several forms of digital storytelling, outlines frameworks and outcomes associated with their use, and promotes digital storytelling as providing new opportunities for humanities scholarship and teaching, especially with regard to critical thinking, communication, digital literacy, and civic engagement.

  20. Unpacking University-Community Partnerships to Advance Scholarship of Practice.

    Science.gov (United States)

    Suarez-Balcazar, Yolanda; Mirza, Mansha Parven; Hansen, Anne Marie Witchger

    2015-01-01

    Today, more than ever, occupational therapists are engaged in close partnerships with community organizations and community settings such as service agencies, refugee and immigrant enclaves, and faith-based organizations, to name a few, for the purpose of engaging in scholarship of practice. However, we know little about the views of community partners regarding the development and sustainability of university-community partnerships. The purpose of this article is twofold: First, we will describe a pilot study in which we gathered qualitative data from community partners engaged in scholarship of practice with faculty and students, regarding their views about benefits of partnerships, challenges, and characteristics of sustainable partnerships. Second, based on this pilot study and extensive experience of the authors, we propose a revised version of a partnerships model available in the literature. We illustrate the model through examples of the authors' collective experiences developing and sustaining successful university-community partnerships.

  1. The Rigour–Relevance Balance for Engaged Scholarship

    DEFF Research Database (Denmark)

    Li, Peter Ping

    2011-01-01

    and positioning JTR, my editorial has five parts. First, I present the key information about JTR. Second, I discuss the major challenges to scholarship in general and rigourrelevance balance in particular. Third, I propose a new frame of thinking capable of addressing those key challenges. Fourth, I introduce......With great excitement, I introduce the Journal of Trust Research (JTR). JTR is positioned as a high-impact source journal for both scholars and practitioners with the critical insights into the unique features and roles of trust within and across disciplines. For the purpose of introducing...... the four articles in the inaugural issue of JTR. Finally, I discuss the agenda for future trust research. The central theme of this editorial is that we must commit to engaged scholarship through the rigourrelevance balance, which is made possible by adopting a new frame of thinking with its holistic...

  2. Engaged Scholarship in Research on Information Technology in Government

    DEFF Research Database (Denmark)

    Medaglia, Rony

    2012-01-01

    -creation, and action research. Using Van de Ven's framework of ‘engaged scholarship’, this paper reports an analysis of 55 empirical studies on impacts of IT in government published in international journals in the period 2003–2009, assessing the presence of stakeholder involvement in the problem formulations, theory....... The paper concludes by providing inputs for a discussion on the role of engaged scholarship in research on IT in the public sector....

  3. A theory-informed, process-oriented Resident Scholarship Program.

    Science.gov (United States)

    Thammasitboon, Satid; Darby, John B; Hair, Amy B; Rose, Karen M; Ward, Mark A; Turner, Teri L; Balmer, Dorene F

    2016-01-01

    The Accreditation Council for Graduate Medical Education requires residency programs to provide curricula for residents to engage in scholarly activities but does not specify particular guidelines for instruction. We propose a Resident Scholarship Program that is framed by the self-determination theory (SDT) and emphasize the process of scholarly activity versus a scholarly product. The authors report on their longitudinal Resident Scholarship Program, which aimed to support psychological needs central to SDT: autonomy, competence, and relatedness. By addressing those needs in program aims and program components, the program may foster residents' intrinsic motivation to learn and to engage in scholarly activity. To this end, residents' engagement in scholarly processes, and changes in perceived autonomy, competence, and relatedness were assessed. Residents engaged in a range of scholarly projects and expressed positive regard for the program. Compared to before residency, residents felt more confident in the process of scholarly activity, as determined by changes in increased perceived autonomy, competence, and relatedness. Scholarly products were accomplished in return for a focus on scholarly process. Based on our experience, and in line with the SDT, supporting residents' autonomy, competence, and relatedness through a process-oriented scholarship program may foster the curiosity, inquisitiveness, and internal motivation to learn that drives scholarly activity and ultimately the production of scholarly products.

  4. Idiopathic pretracheal deep neck space infection with mediastinal extension: A series of 3 cases and review of the literature.

    Science.gov (United States)

    Roberts, Samuel; Chan, Lyndon; Eisenberg, Robert

    2017-06-01

    Idiopathic pretracheal deep neck space infection is an extremely rare condition with potentially devastating complications. We present a series of 3 cases of pretracheal deep neck space infection that arose in the absence of trauma or a congenital lesion and that exhibited mediastinal spread. To the best of our knowledge, these cases represent the first reported series of this rare condition to be published in the English-language literature. All cultures grew Streptococcus milleri, and all patients had a favorable outcome. A high index of suspicion for a deep neck space infection is warranted in view of the devastating complications of this condition. Computed tomography is the investigation of choice. Treatment with intravenous antibiotics and surgical drainage, particularly when mediastinitis is present, is recommended. This rare presentation warrants a thorough investigation to identify the source of infection.

  5. Review of the type series of Pterocles exustus Temminck, 1825 (Aves, Pterocliformes, Pteroclidae) and designation of a lectotype.

    Science.gov (United States)

    Gouraud, Christophe; Frahnert, Sylke; Gamauf, Anita; van der Mije, Steven

    2016-01-01

    The type locality of Pterocles exustus Temminck, 1825, is 'West coast of Africa, Egypt and Nubia'. This is problematic because it includes the type locality of Pterocles exustus floweri (Nicoll, 1921), which is Fayum, Egypt. In the interest of clarification and to preserve stability of nomenclature, a non-Egyptian specimen from the type series of Pterocles exustus is designated as lectotype of the taxon, and the type locality is restricted to Senegal.

  6. Review of the type series of Pterocles exustus Temminck, 1825 ( Aves , Pterocliformes , Pteroclidae ) and designation of a lectotype

    OpenAIRE

    Gouraud, Christophe; Frahnert, Sylke; Gamauf, Anita; van der Mije,Steven

    2016-01-01

    Abstract The type locality of Pterocles exustus Temminck, 1825, is ?West coast of Africa, Egypt and Nubia?. This is problematic because it includes the type locality of Pterocles exustus floweri (Nicoll, 1921), which is Fayum, Egypt. In the interest of clarification and to preserve stability of nomenclature, a non-Egyptian specimen from the type series of Pterocles exustus is designated as lectotype of the taxon, and the type locality is restricted to Senegal.

  7. Ischemic Gastritis: A Multicenter Case Series of a Rare Clinical Entity and a Review of the Literature.

    Science.gov (United States)

    Elwir, Saleh; Shaukat, Aasma; Mesa, Hector; Colbach, Christine; Dambowy, Paul; Shaw, Michael

    2016-10-01

    To report a case series of ischemic gastritis and discuss its etiology, management, and associated mortality according to our results and the published English literature. Ischemic gastritis is rare, given the rich blood supply of the stomach. It has been reported in isolated case reports and small case series. Most cases are vascular in origin and associated with a high mortality. Pathology databases from 3 hospitals affiliated with the University of Minnesota Medical School were searched for cases of ischemic gastritis in the last 10 years. Patients' demographics, clinical course, and 1-month and 1-year mortalities were collected from electronic medical records. A total of 12 patients were identified (age range, 32.1 to 83.2), the largest series reported to date. The presenting symptom was gastrointestinal bleeding (8), abdominal pain (2), nausea (1), and symptomatic anemia (1). The etiology included postinterventional radiology embolization (2), hemodynamic changes in the setting of celiac axis stenosis (2), vasculitis (1), systemic hypotension (1), and unknown (6). Treatment included steroid therapy, revascularization by interventional radiology, surgery, or supportive treatment. Thirty-day and 1-year mortalities were 33% and 41%, respectively. Ischemic gastritis is rare, but associated with a high mortality. Evaluation for treatable etiologies should be sought and corrected if present.

  8. Clarifying the distinction between case series and cohort studies in systematic reviews of comparative studies: potential impact on body of evidence and workload

    Directory of Open Access Journals (Sweden)

    Tim Mathes

    2017-07-01

    Full Text Available Abstract Distinguishing cohort studies from case series is difficult. We propose a conceptualization of cohort studies in systematic reviews of comparative studies. The main aim of this conceptualization is to clarify the distinction between cohort studies and case series. We discuss the potential impact of the proposed conceptualization on the body of evidence and workload. All studies with exposure-based sampling gather multiple exposures (with at least two different exposures or levels of exposure and enable calculation of relative risks that should be considered cohort studies in systematic reviews, including non-randomized studies. The term “enables/can” means that a predefined analytic comparison is not a prerequisite (i.e., the absolute risks per group and/or a risk ratio are provided. Instead, all studies for which sufficient data are available for reanalysis to compare different exposures (e.g., sufficient data in the publication are classified as cohort studies. There are possibly large numbers of studies without a comparison for the exposure of interest but that do provide the necessary data to calculate effect measures for a comparison. Consequently, more studies could be included in a systematic review. Therefore, on the one hand, the outlined approach can increase the confidence in effect estimates and the strengths of conclusions. On the other hand, the workload would increase (e.g., additional data extraction and risk of bias assessment, as well as reanalyses.

  9. Clarifying the distinction between case series and cohort studies in systematic reviews of comparative studies: potential impact on body of evidence and workload.

    Science.gov (United States)

    Mathes, Tim; Pieper, Dawid

    2017-07-17

    Distinguishing cohort studies from case series is difficult.We propose a conceptualization of cohort studies in systematic reviews of comparative studies. The main aim of this conceptualization is to clarify the distinction between cohort studies and case series. We discuss the potential impact of the proposed conceptualization on the body of evidence and workload.All studies with exposure-based sampling gather multiple exposures (with at least two different exposures or levels of exposure) and enable calculation of relative risks that should be considered cohort studies in systematic reviews, including non-randomized studies. The term "enables/can" means that a predefined analytic comparison is not a prerequisite (i.e., the absolute risks per group and/or a risk ratio are provided). Instead, all studies for which sufficient data are available for reanalysis to compare different exposures (e.g., sufficient data in the publication) are classified as cohort studies.There are possibly large numbers of studies without a comparison for the exposure of interest but that do provide the necessary data to calculate effect measures for a comparison. Consequently, more studies could be included in a systematic review. Therefore, on the one hand, the outlined approach can increase the confidence in effect estimates and the strengths of conclusions. On the other hand, the workload would increase (e.g., additional data extraction and risk of bias assessment, as well as reanalyses).

  10. Holmium:YAG Laser Ablation for the Management of Lower Urinary Tract Foreign Bodies Following Incontinence Surgery: A Case Series and Systematic Review.

    Science.gov (United States)

    Chan, Garson; Mamut, Adiel; Martin, Paul; Welk, Blayne

    2016-11-01

    The objective of this study was to determine the outcomes associated with the endoscopic removal of foreign bodies (such as mesh or permanent suture) in the lower urinary tract after female stress incontinence surgery with the Holmium:YAG (Ho:YAG) laser, and to systematically review the literature on this topic. A retrospective chart review of 18 consecutive women found to have mesh or suture exposure was performed. All patients underwent Ho:YAG laser ablation. A systematic review was performed to identify literature addressing the endoscopic management of mesh/suture exposure after stress incontinence surgery. Between November 2011 and February 2016, 18 women underwent Ho:YAG laser ablation of exposed mesh or suture. Presenting symptoms included lower urinary tract symptoms, pelvic pain, incontinence, or recurrent urinary tract infections. Thirteen women had a previous synthetic midurethral sling and five had a prior retropubic suspension. The median age was 58 years (interquartile range [IQR] 50-60) and median follow-up was 2 years (IQR 1-2). Four patients (22%) had residual mesh after the first procedure, requiring a repeat endoscopic procedure. Only one patient had a small amount of asymptomatic residual mesh on cystoscopy after the final procedure. Only minor postoperative complications were observed. Eight patients had stress incontinence and four underwent operative treatment for this. In our systematic review, we identified 16 case series, which described a total of 158 patients. Women most commonly presented with voiding symptoms or incontinence. Based on the synthesis of these data, repeat procedures were necessary in 16% and vesicovaginal fistula occurred in 2%. Recurrent/persistent stress incontinence was present in 20%, and of these patients, 3/4 underwent a new stress incontinence procedure. Both our case series and the systematic review of the literature demonstrated that endoscopic treatment of lower urinary tract foreign bodies after stress

  11. AHRQ series on complex intervention systematic reviews-paper 6: PRISMA-CI extension statement and checklist.

    Science.gov (United States)

    Guise, Jeanne-Marie; Butler, Mary E; Chang, Christine; Viswanathan, Meera; Pigott, Terri; Tugwell, Peter

    2017-10-01

    Complex interventions are widely used in health systems, public health, education, and communities and are increasingly the subject of systematic reviews. Oversimplification and inconsistencies in reporting about complex interventions can limit the usability of review findings. Although guidance exists to ensure that reports of individual studies and systematic reviews adhere to accepted scientific standards, their design-specific focus leaves important reporting gaps relative to complex interventions in health care. This paper provides a stand-alone extension to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting tool for complex interventions-PRISMA-CI-to help authors, publishers, and readers understand and apply to systematic reviews of complex interventions. PRISMA-CI development followed the Enhancing the QUAlity and Transparency Of health Research Network guidance for extensions and focused on adding or modifying only essential items that are truly unique to complex interventions and are not covered by broader interpretation of current PRISMA guidance. PRISMA-CI provides an important structure and guidance for systematic reviews and meta-analyses for the highly prevalent and dynamic field of complex interventions. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  12. Systematic literature reviews and meta-analyses: part 6 of a series on evaluation of scientific publications.

    Science.gov (United States)

    Ressing, Meike; Blettner, Maria; Klug, Stefanie J

    2009-07-01

    Because of the rising number of scientific publications, it is important to have a means of jointly summarizing and assessing different studies on a single topic. Systematic literature reviews, meta-analyses of published data, and meta-analyses of individual data (pooled reanalyses) are now being published with increasing frequency. We here describe the essential features of these methods and discuss their strengths and weaknesses. This article is based on a selective literature search. The different types of review and meta-analysis are described, the methods used in each are outlined so that they can be evaluated, and a checklist is given for the assessment of reviews and meta-analyses of scientific articles. Systematic literature reviews provide an overview of the state of research on a given topic and enable an assessment of the quality of individual studies. They also allow the results of different studies to be evaluated together when these are inconsistent. Meta-analyses additionally allow calculation of pooled estimates of an effect. The different types of review and meta-analysis are discussed with examples from the literature on one particular topic. Systematic literature reviews and meta-analyses enable the research findings and treatment effects obtained in different individual studies to be summed up and evaluated.

  13. Infinite series

    CERN Document Server

    Hirschman, Isidore Isaac

    2014-01-01

    This text for advanced undergraduate and graduate students presents a rigorous approach that also emphasizes applications. Encompassing more than the usual amount of material on the problems of computation with series, the treatment offers many applications, including those related to the theory of special functions. Numerous problems appear throughout the book.The first chapter introduces the elementary theory of infinite series, followed by a relatively complete exposition of the basic properties of Taylor series and Fourier series. Additional subjects include series of functions and the app

  14. Scholarship reconsidered: implications for reward and recognition of academic staff in schools of nursing and beyond.

    Science.gov (United States)

    Smith, Kylie M; Crookes, Patrick A; Else, Fabienne; Crookes, Ellie

    2012-03-01

    This paper discusses the issues facing the nursing academic workforce and the development of a project at the University of Wollongong in Australia which attempts to address this problem. The project draws on Boyer's work around 'scholarship reconsidered' to enable new ways of thinking about the nature of 'research' and how the work of a diversifying workforce can be recognized and rewarded within institutions. We conducted a series of interviews with senior university staff to identify key issues around academic promotion processes. Feedback from these interviews, along with extensive internal and external consultation and benchmarking, will be used to redraft promotion documentation that includes discipline-specific performance expectations. Interviews revealed a number of perceived and actual barriers to promotion of academic staff who did not conform to a 'traditional' view of research expectations. It was widely felt that unspoken expectations about research performance were being used to judge applications for promotion, and that this disadvantaged people from practice or professional backgrounds, or people who had heavy administrative or clinical roles. Internal university processes need to reflect the reality of a diversified workforce. Practice and professional disciplines have responsibilities beyond meeting traditional research output measurements. More flexible and transparent expectation guidelines and career development pathways are needed to build holistic schools and faculty and enable maximum staff productivity. By redefining scholarship, schools and faculties are able to meet the multiple demands of the government, the institution, individual staff, students and the profession. Not everyone can do traditional research all the time, and staff involved in other scholarly work should be able to rewarded and promoted. By taking the lead in this issue, nursing as a discipline can set its own agenda, and pave the way for other disciplines. It can also

  15. EXCEPTIONAL COLLOQUIUM : Digital scholarship and the changing nature of scientific publication

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    Digital media have extended the number of channels that scientists (and other academics) use to communicate and share information. Digital technologies have the potential to make all stages of the research process more visible in the public sphere, and to audiences that have, on occasion, opportunities for interaction and engagement. But digital technologies also are introducing novel demands on researchers, requiring skills and competencies on the part of scientists that are encapsulated by the concept of digital scholarship. In this presentation we explore this developing context via a case study: the publication of emails from the Climatic Research Unit at the University of East Anglia (also known as ‘climategate’). The findings of three reviews of ‘climategate’ will be discussed in terms of their implications for science communication. This episode may indirectly influence the ways that scientific knowledge is produced and verified, and what information and data are required to be archived for cir...

  16. Role for Occupational Therapy in Community Mental Health: Using Policy to Advance Scholarship of Practice.

    Science.gov (United States)

    Mahaffey, Lisa; Burson, Kathrine A; Januszewski, Celeste; Pitts, Deborah B; Preissner, Katharine

    2015-01-01

    Occupational therapists must be aware of professional and policy trends. More importantly, occupational therapists must be involved in efforts to influence policy both for the profession and for the people they serve (Bonder, 1987). Using the state of Illinois as an example, this article reviews the policies and initiatives that impact service decisions for persons with psychiatric disabilities as well as the rationale for including occupational therapy in community mental health service provision. Despite challenges in building a workforce of occupational therapists in the mental health system, this article makes the argument that the current climate of emerging policy and litigation combined with the supporting evidence provides the impetus to strengthen mental health as a primary area of practice. Implications for scholarship of practice related to occupational therapy services in community mental health programs for individuals with psychiatric disability are discussed.

  17. Bridging international relations and disaster studies: the case of disaster-conflict scholarship.

    Science.gov (United States)

    Hollis, Simon

    2018-01-01

    International relations and disaster studies have much to gain by thinking critically about their respective theoretical and epistemological assumptions. Yet, few studies to date have sought to assess the potential value of linking these two disciplines. This paper begins to address this shortfall by examining the relationship between disasters and conflict as a research sphere that intersects international relations and disaster studies. Through an analysis of whether or not disasters contribute to intra-national and international conflict, this paper not only provides a review of the state of the art, but also serves to invite scholars to reflect on related concepts from other fields to strengthen their own approaches to the study of disasters in an international setting. An evaluation of the conceptual and theoretical contributions of each subject area provides useful heuristics for the development of disaster-conflict scholarship and encourages alternative modes of knowledge production through interdisciplinarity. © 2018 The Author(s). Disasters © Overseas Development Institute, 2018.

  18. Elevated human chorionic gonadotropin levels in patients with chronic kidney disease: Case series and review of literature

    Directory of Open Access Journals (Sweden)

    S Soni

    2013-01-01

    Full Text Available Women are often subjected to serum human chorionic gonadotropin (HCG testing prior to diagnostic and therapeutic interventions. A positive result leads to further testing to rule out pregnancy and avoid possible fetal teratogenicity. The impact of chronic kidney disease (CKD on HCG testing has not been studied. We report a series of 5 women out of 62 with CKD, who had a positive HCG test on routine pre-transplant screening at a single transplant center. We analyzed their case records retrospectively. Despite aggressive investigation, their elevated HCG levels remained unexplained. The positive test contributed to delays in transplantation and increased overall cost of treatment.

  19. Diagnosis and Management of Transplanted Kidney Extrarenal Pseudoaneurysms: A Series of Four Cases and a Review of the Literature

    Energy Technology Data Exchange (ETDEWEB)

    Fananapazir, Ghaneh, E-mail: fananapazir@ucdavis.edu [University of California Davis Medical Center, Department of Radiology (United States); Hannsun, Gemmy [University of California Sacramento Medical Center, School of Medicine (United States); Wright, Luke A.; Corwin, Michael T. [University of California Davis Medical Center, Department of Radiology (United States); Troppmann, Christoph [University of California Davis Medical Center, Department of Surgery (United States)

    2016-11-15

    Extrarenal pseudoaneurysms of transplanted kidneys are very rare but can have devastating consequences. In the past, these extrarenal pseudoaneurysms have often led to graft loss as well as significant morbidity and mortality. The role of advanced diagnostic imaging studies and of modern radiologic interventional management has not been studied. In this case series, we present four cases of extrarenal pseudoaneurysms of transplanted kidneys, describe the clinical scenarios and imaging that led to the angiographic diagnosis, and discuss the various endovascular and surgical approaches to management.

  20. Varieties of integrative scholarship: why rules of evidence, criteria, and standards matter.

    Science.gov (United States)

    McGaghie, William C

    2015-03-01

    Integrative scholarship involves the aggregation of data and evidence in a way that allows the research community to comprehend and value the connections and perspectives that unite isolated facts and research studies. Integrative scholarship summarizes data, enlightens and informs readers broadly, and sets the stage for subsequent research. This article describes five approaches to integrative scholarship--narrative, systematic, scoping, critical-realist, open peer commentary--and argues that each approach uses different methods and rules of evidence to combine data and report their meaning. Different forms of integrative scholarship use methods, criteria, and standards that are matched to the integrative approach and data being evaluated. There is no one best strategy to conduct or judge integrative scholarship. Researchers who perform integrative scholarship should openly express the values that underlie their work.

  1. Six Memos for a Curious and Imaginative Future Scholarship in Entrepreneurship Studies

    DEFF Research Database (Denmark)

    Steyaert, Chris; Hjorth, Daniel; Gartner, William B.

    2011-01-01

    boundaries, affecting community scholarship and entrepreneurship education, contextualizing through participation and reconceptualizing method. In the conclusion, we emphasize for the future the importance of a curious and imaginative scholarship in entrepreneurship, a utopian movement that attracts...... commemorative and affirmative, that is we use the work of Johannisson to explore fresh waters and invent new practices of performing scholarship in entrepreneurship studies. In the special issue, six practices are proposed that keep entrepreneurship studies imaginative: othering words and concepts, exploring...

  2. Education scholarship in emergency medicine part 3: a "how-to" guide.

    Science.gov (United States)

    Bhanji, Farhan; Cheng, Adam; Frank, Jason R; Snell, Linda; Sherbino, Jonathan

    2014-05-01

    Successful emergency medicine (EM) education scholarship requires a systematic approach that includes searching the (grey) literature, mobilizing resources, adopting frameworks to focus the innovation, integrating a component of program evaluation, and disseminating the innovation via traditional and emerging avenues. This paper provides direction for EM teachers and educators looking to transform their education innovation into scholarship. Recommendations on producing EM education scholarship from the 2013 consensus conference of the Academic Section of the Canadian Association of Emergency Physicians are presented.

  3. Marginalization: A Revisitation With Integration of Scholarship on Globalization, Intersectionality, Privilege, Microaggressions, and Implicit Biases.

    Science.gov (United States)

    Hall, Joanne M; Carlson, Kelly

    2016-01-01

    In 1994, the concept of marginalization was explored in an article in Advances in Nursing Science. This is a revisitation of the concept incorporating new scholarship. This update is founded on feminism, postcolonialism, critical race theory, and discourse deconstruction, all viewpoints that have been explicated in nursing. The purpose of this analysis is to look at new scholarship and concepts useful to applying marginalization in nursing knowledge development from the standpoint of Bourdieu's macro, meso, and micro levels. New scholarship includes globalization, intersectionality, privilege, microaggressions, and implicit bias. Implications for decreasing health disparities through this new scholarship are discussed.

  4. Acute genital ulcers in nonsexually active young girls: case series, review of the literature, and evaluation and management recommendations.

    Science.gov (United States)

    Rosman, Ilana S; Berk, David R; Bayliss, Susan J; White, Andrew J; Merritt, Diane F

    2012-01-01

    Acute genital ulcers rarely occur in nonsexually active young girls. When present, they can cause significant physical and emotional distress for the patient and her parents, and prompt an evaluation for sexual abuse and sexually transmitted diseases. With this review, we aim to further characterize acute genital ulcers in nonsexually active young girls by reviewing the medical records of patients with this disorder and to offer an approach to the diagnosis, evaluation, and treatment of acute genital ulcers based on our understanding and knowledge of this condition. We retrospectively review our understanding and knowledge of acute genital ulcers in nonsexually active girls at a pediatric hospital. A review of the recent literature on acute genital ulcers and a multidisciplinary approach to the diagnosis, evaluation, and treatment of acute genital ulcers are also presented. Twelve patients presented with acute genital ulcers, 11 of which were hospitalized for evaluation and pain management. Extensive work-up failed to reveal a specific infectious or autoimmune etiology in all but one patient, who was diagnosed with acute mycoplasma pneumonia. Acute genital ulcers in nonsexually active young girls likely represent a form of idiopathic vulvar aphthosis. Evaluation of a first episode of acute genital ulcers with mild prodromal symptoms should be limited. Treatment consists primarily of supportive care and symptom relief. © 2012 Wiley Periodicals, Inc.

  5. Multivariable and Bayesian Network Analysis of Outcome Predictors in Acute Aneurysmal Subarachnoid Hemorrhage: Review of a Pure Surgical Series in the Postinternational Subarachnoid Aneurysm Trial Era.

    Science.gov (United States)

    Zador, Zsolt; Huang, Wendy; Sperrin, Matthew; Lawton, Michael T

    2017-07-31

    Following the International Subarachnoid Aneurysm Trial (ISAT), evolving treatment modalities for acute aneurysmal subarachnoid hemorrhage (aSAH) has changed the case mix of patients undergoing urgent surgical clipping. To update our knowledge on outcome predictors by analyzing admission parameters in a pure surgical series using variable importance ranking and machine learning. We reviewed a single surgeon's case series of 226 patients suffering from aSAH treated with urgent surgical clipping. Predictions were made using logistic regression models, and predictive performance was assessed using areas under the receiver operating curve (AUC). We established variable importance ranking using partial Nagelkerke R 2 scores. Probabilistic associations between variables were depicted using Bayesian networks, a method of machine learning. Importance ranking showed that World Federation of Neurosurgical Societies (WFNS) grade and age were the most influential outcome prognosticators. Inclusion of only these 2 predictors was sufficient to maintain model performance compared to when all variables were considered (AUC = 0.8222, 95% confidence interval (CI): 0.7646-0.88 vs 0.8218, 95% CI: 0.7616-0.8821, respectively, DeLong's P = .992). Bayesian networks showed that age and WFNS grade were associated with several variables such as laboratory results and cardiorespiratory parameters. Our study is the first to report early outcomes and formal predictor importance ranking following aSAH in a post-ISAT surgical case series. Models showed good predictive power with fewer relevant predictors than in similar size series. Bayesian networks proved to be a powerful tool in visualizing the widespread association of the 2 key predictors with admission variables, explaining their importance and demonstrating the potential for hypothesis generation.

  6. Development of the personalized criteria for microscopic review following four different series of hematology analyzer in a Chinese large scale hospital.

    Science.gov (United States)

    Cui, Wei; Wu, Wei; Wang, Xin; Wang, Geng; Hao, Ying-Ying; Chen, Yu; Luo, Dan; Shou, Wei-Ling; Zhang, Shuo; Xiang, Xue-Fang; Si, Yong-Zhen; Chen, Qian; Cai, Hao; Li, Tan; Shen, Han; Shang, Kun; Zhang, Yong-Qiang

    2010-11-01

    A generally accepted guideline ("41 rules") published by the International Consensus Group for Hematology Review (ICGHR) can not be suitable for all the laboratories because the facility type, laboratory requirements, sample volume, review rate, turn around time, instrument model and characters etc. are quite different from each other, which may cause a higher workload for microscopy review or lead to false or misleading results. Therefore, we decided to develop the personalized review criteria for 4 series of hematology analyzers in the same hospital, and describe all the implement procedures in detail. The total 1770 blood samples were collected from Peking Union Medical College Hospital. Referring to the suggested criteria by international consensus group for hematology review ("41 rules"), the personalized review criteria for 4 series of hematology analyzers including Siemens Advia 2120, Sysmex XE-2100, Sysmex XT-1800i and Sysmex XS-800i were established and validated by adjusting the rules in order to reduce the false positive rate and keep the false negative acceptable by clinical. Using the "41 rules", high review rates of 37.94%, 35.56%, 33.44% and 37.94% were got respectively in Siemens Advia 2120, Sysmex XE-2100, Sysmex XT-1800i and Sysmex XS-800i. Three false positive rules mainly were observed in all of 4 analyzers: white blood cell 30 × 10(9)/L, platelet 1000 × 10(9)/L and immature granulocyte. Specialized rules were observed in different series of analyzers, atypical/variant lymphs flag were found mainly in Sysmex XE-2100, Aniso-RBC were found mainly in Sysmex XT-1800i, flag of "immature granulocyte" mainly in Sysmex XS-800i, Micro-RBC, Macro-RBC and Aniso-RBC mainly in Siemens Advia 2120. Rules of immature granulocyte, blast, and NRBC flag would be mainly triggered by hematology malignant tumor. We could not delete these rules due to the risk of false negative of serious disease, other rules were deleted or revised. After continually optimizing to

  7. Conservative management of large radicular cysts associated with non-vital primary teeth: A case series and literature review

    Directory of Open Access Journals (Sweden)

    K S Uloopi

    2015-01-01

    Full Text Available Radicular cysts are the most common odontogenic cystic lesions of inflammatory origin. Large radicular cyst is comparatively less frequently associated with primary teeth. They represent only 0.5-3.3% of the total number of cysts in primary dentition. Radicular cysts arising from deciduous teeth are reported to occur in age range of 3-19 years with a male predominance. Although large radicular cysts are treated by enucleation with extensive removal of bone and vital teeth, marsupialization can be preferred as a conservative approach to reduce the morbidity. The purpose of this article is to report a case series of large radicular cysts associated with badly mutilated and traumatized primary teeth and to demonstrate how best they can be conservatively treated during mixed dentition period.

  8. Conservative management of large radicular cysts associated with non-vital primary teeth: a case series and literature review.

    Science.gov (United States)

    Uloopi, K S; Shivaji, Raju U; Vinay, C; Shrutha, S P; Chandrasekhar, R

    2015-01-01

    Radicular cysts are the most common odontogenic cystic lesions of inflammatory origin. Large radicular cyst is comparatively less frequently associated with primary teeth. They represent only 0.5-3.3% of the total number of cysts in primary dentition. Radicular cysts arising from deciduous teeth are reported to occur in age range of 3-19 years with a male predominance. Although large radicular cysts are treated by enucleation with extensive removal of bone and vital teeth, marsupialization can be preferred as a conservative approach to reduce the morbidity. The purpose of this article is to report a case series of large radicular cysts associated with badly mutilated and traumatized primary teeth and to demonstrate how best they can be conservatively treated during mixed dentition period.

  9. Papillon-Lefèvre syndrome: A series of three cases in the same family and a literature review.

    Science.gov (United States)

    Upadhyaya, Jasbir D; Pfundheller, Dustin; Islam, Mohammed N; Bhattacharyya, Indraneel

    2017-01-01

    Papillon-Lefèvre syndrome (PLS) is a rare autosomal recessive disorder that exhibits palmoplantar keratosis and early severe periodontitis. The oral disease affects both the primary and permanent dentitions leading to premature exfoliation of teeth. Various etiologic factors, such as genetic mutations, immunologic alterations, and bacteria have been implicated in PLS. Genetic mutations leading to the loss of function of cathepsin C (CTSC) gene, located on chromosome 11q14, is considered pivotal in this condition. The present case series describes PLS in three siblings, with consanguineously married parents, who live in a remote area of Yemen. The affected children presented with prominent palmoplantar keratosis and early periodontitis with only a few remaining teeth. The severity of skin lesions in all patients exhibited seasonal variations. Based on their clinical findings, a diagnosis of PLS was made. Dentists have a significant role in the early diagnosis and management of PLS patients.

  10. Dual Anchor Internal Pulse Generator Technique May Lower Risk of Twiddler's Syndrome: A Case Series and Literature Review.

    Science.gov (United States)

    Sobstyl, Michał Roman; Ząbek, Mirosław; Brzuszkiewicz-Kuźmicka, Grażyna; Pasterski, Tomasz

    2017-08-01

    Twiddler's syndrome (TS) is described as a spontaneous rotation or intentional external manipulation of implanted internal pulse generator (IPG) for neurological or cardiac disorders. There have been identified some predisposing factors of the development of TS such as: loose subcutaneous tissue, older age of individuals undergoing deep brain stimulation (DBS) procedures, creation of too large pockets for IPG. Apart from these factors, the construction of IPG itself may predispose to the development of TS. To report the clinical course of three patients with TS. Moreover, the purpose of this study is to present the change in fixation technique of IPG that can prevent the occurrence of TS in patients after DBS procedure. A prospectively collected database of all hardware related complications for patients operated on for various movement disorders was analyzed. In a total number of 347 DBS systems implanted since 1999 we have identified three patients diagnosed with TS. All three patients with TS in our series were implanted with the IPG harboring a single anchoring hole. This complication has never occurred in patients with the IPG harboring two anchoring holes in our center. All three patients underwent revision surgery. During reoperations all connection cables were replaced and IPG sutured with one additional silk stich through the plastic housing to immobilize it properly in subcutaneous pocket. There were no recurrences of TS in our patients. Our case series suggests that a predisposing factor of TS may also be the construction of IPG itself (a single anchoring hole intended for fixation), which naturally represents less fixation of the IPG to the fascia or muscle in the subcutaneous pocket. In this preliminary report we present suggestions to lower the risk of TS, including using dual anchor capable IPGs, reducing pocket volume and using nonabsorbable suture. © 2017 International Neuromodulation Society.

  11. Postoperative survival and functional outcomes for patients with metastatic gynecological cancer to the spine: case series and review of the literature.

    Science.gov (United States)

    Liu, Ann; Sankey, Eric W; Goodwin, C Rory; Kosztowski, Thomas A; Elder, Benjamin D; Bydon, Ali; Witham, Timothy F; Wolinsky, Jean-Paul; Gokaslan, Ziya L; Sciubba, Daniel M

    2016-01-01

    Spinal metastases from gynecological cancers are rare, with few cases reported in the literature. In this study, the authors examine a series of patients with spinal metastases from gynecological cancer and review the literature. The cases of 6 consecutive patients who underwent spine surgery for metastatic gynecological cancer between 2007 and 2012 at a single institution were retrospectively reviewed. The recorded demographic, operative, and postoperative factors were reviewed, and the functional outcomes were determined by change in Karnofsky Performance Scale and the American Spine Injury Association (ASIA) score during follow-up. A systematic review of the literature was also performed to evaluate outcomes for patients with similar gynecological metastases to the spine. In this series, details regarding metastatic gynecological cancers to the spine are as follows: 2 patients with cervical cancer (both presented at age 46 years, mean postoperative survival of 32 months), 2 patients with endometrial cancer (mean age of 40 years, mean postoperative survival of 26 months), and 2 patients with leiomyosarcoma (mean age of 44 years, mean postoperative survival of 20 months). All patients presented with pain, and no complications were noted following surgery. All patients with known follow-up had stable or improved neurological outcomes, performance status, and improved pain, without local recurrence of tumor. Overall median survival after diagnosis of metastatic spine lesions for all cases in the literature as well as those treated by the authors was 15 months. When categorized by type, median survival of patients with cervical cancer (n = 2), endometrial cancer (n = 26), and leiomyosarcoma (n = 16) was 32, 10, and 22.5 months, respectively. Gynecological cancers metastasizing to the spine are rare. In this series, overall survival following diagnosis of spinal metastasis and surgery was 27 months, with cervical cancer, endometrial cancer, and leiomyosarcoma survival

  12. Low efficacy of metronidazole in the eradication of Blastocystis hominis in symptomatic patients: Case series and systematic literature review.

    Science.gov (United States)

    Batista, Lissette; Pérez Jove, Josefa; Rosinach, Mercè; Gonzalo, Victoria; Sainz, Empar; Loras, Carme; Forné, Montserrat; Esteve, Maria; Fernández-Bañares, Fernando

    Blastocystis hominis (B. hominis) is a protozoan commonly found in the gastrointestinal tract. There are doubts about its clinical significance. Metronidazole (MTZ) is the recommended first-line treatment. A retrospective review was carried out between 2011 and 2012. A total of 151 samples were randomly selected from 383 samples positive for B. hominis. Inclusion criteria were: suggestive symptoms, treatment indication and microbiological follow-up. A systematic review was performed of all studies that evaluated the effect of MTZ on B. hominis infection. Forty-six patients met the inclusion criteria (64% women; age, 44.2±2 years). MTZ was used in 39 patients, 31 of whom obtained a clinical response (79.5%) but only 15 a microbiological response (48.4%). No dose-effect relationship was observed. Twenty patients with no initial microbiological response received a second round of treatment (MTZ, cotrimoxazole, paramomycin, others), with a microbiological response in 70%. Overall, B. hominis was cured in 72% (95% CI: 57%-83%). Of 54 treatments associated with a clinical response, a microbiological response occurred in 31 (57%), while in the remaining 12 with no clinical response, microbiological cure was observed in only 2 (17%) (P=.022). The eradication rate in the systematic review varied between 0% and 100%. There seems to be a relationship between the clinical and microbiological response to B. hominis treatment. The microbiological response to MTZ treatment is insufficient in our geographical setting. The systematic review shows that the response to MTZ is very variable. Copyright © 2016. Publicado por Elsevier España, S.L.U.

  13. case series

    African Journals Online (AJOL)

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    Conclusions: The concept of “case series” is not well defined in the literature and does not reflect a specific research design. We suggest that a case series should have more than four patients while four paitents or less should be reported individually as case reports. Key words: Case report, case series, concept analysis, ...

  14. Deadly intracranial bleed in patients with dengue fever: A series of nine patients and review of literature.

    Science.gov (United States)

    Sam, Jo Ee; Gee, Teak Sheng; Nasser, Abdul Wahab

    2016-01-01

    Dengue fever is a global pandemic threat with increasing incidence. To date, there are no cures and the effectiveness of dengue vaccines is still uncertain. World Heath Organization introduced expanded dengue syndrome to include unusual presentations of dengue fever including severe neurologic complications. One of the deadly complications is intracranial hemorrhage (ICH). We collected data of patients with ICH diagnosed via a plain computed tomography of the brain (CT brain) with thrombocytopenia and positive Dengue virus type 1 nonstructural protein (NS1) antigen test or positive dengue serology IgM from January 2014 till June 2015 at our center. Nine patients were included and all 20 other remaining patients reported in literature so far are discussed. We found that all patients in our center requiring neurosurgical intervention died. Another interesting observation is that detection of Dengue IgG usually meant more severe ICH and poorer outcomes. From our series, platelet levels did not seem to influence the outcome. We recommend that for early detection of ICH, Dengue IgG should be routinely screened and a high index of suspicion be maintained. Future research should be focused on determining predictors of ICH in patients with dengue fever so that preventive steps can be taken as mortality is high and no treatment seems beneficial at the moment once severe ICH occurs.

  15. Long-term follow-up of choroidal neovascularization secondary to angioid streaks: case series and literature review

    Directory of Open Access Journals (Sweden)

    Al-Rashaed S

    2012-07-01

    Full Text Available Saba Al-Rashaed, J Fernando ArevaloKing Khaled Eye Specialist Hospital, Riyadh, Saudi ArabiaBackground: The purpose of this paper is to report the clinical course of choroidal neovascularization (CNV secondary to angioid streaks and the outcomes in response to different treatment modalities.Methods: This was a case series of two consecutive patients (four eyes with CNV secondary to angioid streaks. Visual acuity, ophthalmological examination, color photographs, fluorescein angiography, and optical coherence tomography were used to assess the outcomes of treatment.Results: Two eyes were treated with photodynamic therapy for subfoveal choroidal neovascular membrane, one eye underwent thermal laser photocoagulation for extrafoveal CNV followed by intravitreal bevacizumab for subfoveal CNV, and one eye underwent intravitreal bevacizumab for subfoveal CNV. The follow-up period was 4–6 years. The final visual acuities of all eyes were 20/300 or worse with large submacular fibrosis.Conclusion: CNV secondary to angioid streaks in these two patients had a poor prognosis despite undergoing different types of treatment. Poor outcome was likely related to frequent recurrence and newly developed CNV, which remained a clinical concern in these cases.Keywords: choroidal neovascular membrane, angioid streaks, intravitreal bevacizumab, photodynamic therapy

  16. The expanding field of poly(ADP-ribosyl)ation reactions. 'Protein Modifications: Beyond the Usual Suspects' Review Series.

    Science.gov (United States)

    Hakmé, Antoinette; Wong, Heng-Kuan; Dantzer, Françoise; Schreiber, Valérie

    2008-11-01

    Poly(ADP-ribosyl)ation is a post-translational modification of proteins that is mediated by poly(ADP-ribose) polymerases (PARPs). Although the existence and nature of the nucleic acid-like molecule poly(ADP-ribose) (PAR) has been known for 40 years, understanding its biological functions--originally thought to be only the regulation of chromatin superstructure when DNA is broken--is still the subject of intense research. Here, we review the mechanisms controlling the biosynthesis of this complex macromolecule and some of its main biological functions, with an emphasis on the most recent advances and hypotheses that have developed in this rapidly growing field.

  17. A review of case and case series reports on Henöch–Schönlein syndrome-related pancreatitis

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    Fei Xiong

    2017-01-01

    Full Text Available To summarize the experience of diagnosing and treating patients with Henoch–Schönlein purpura (HSP-related pancreatitis, a systematic review of previously published cases was conducted. Among 13 reported cases, there were six males and seven females whose age from 3 to 70 years. The clinical features of these patients indicated that acute pancreatitis could be the initial manifestation of HSP, the radiological change was atypical, and most cases were alleviated with steroidal treatment. Good outcomes can be achieved in patients who are diagnosed early with HSP-related pancreatitis, and it is vital to begin timely treatment of HSP-related pancreatitis with corticosteroid.

  18. Tardive dyskinesia in patients treated with atypical antipsychotics: case series and brief review of etiologic and treatment considerations

    Directory of Open Access Journals (Sweden)

    Jungjin Kim

    2014-04-01

    Full Text Available Tardive dyskinesia (TD is a disfiguring side-effect of antipsychotic medications that is potentially irreversible in affected patients. Newer atypical antipsychotics are felt by many to have a lower risk of TD. As a result, many clinicians may have developed a false sense of security when prescribing these medications. We report five cases of patients taking atypical antipsychotics who developed TD, review the risk of TD, its potential etiologic mechanisms, and treatment options available. The goal of this paper is to alert the reader to continue to be diligent in obtaining informed consent and monitoring for the onset of TD in patients taking atypical antipsychotics.

  19. Isotretinoin therapy for the treatment of acne in patients with cystic fibrosis: a case series and review of the literature.

    Science.gov (United States)

    Bari, O; Paravar, T

    2016-03-16

    Cystic fibrosis (CF) is the most common severe autosomal recessive disorder in Caucasians. Viscous secretionstypically obstruct the lungs, pancreas, and gastrointestinal tract. As disease management improves, patients will increasingly seek care for conditions such as acne. Isotretinoin therapy for acne in patients with CF is controversial owing to concerns that the medication may exacerbate CF-related hepatic, pulmonary, and ocular complications. We describe two patients with CF treated with isotretinoin from our clinic and also provide a literature review of 11 similar cases. We describe patient outcomes, common complications, and the risks for severe adverse effects. The clinical courses of two patients with CF who were treated with isotretinoin for moderate-severe acne are presented. Using PubMed, we analyzed previous case reports of patients with CF who were prescribed isotretinoin and review complications associated with systemic retinoids. Based on a synthesis of the literature and our own experience, it appears that isotretinoin therapy for CF patients with moderate-severe acne may be an appropriate option when clinically indi ated. If dermatologists monitor lab values and adverseeffects carefully, patients with CF can benefit from isotretinoin therapy.

  20. Macular edema is a rare finding in untreated vitreoretinal lymphoma: small case series and review of the literature.

    Science.gov (United States)

    Carreras, Elisa; Salomão, Diva R; Nadal, Jeroni; Amin, Sejal R; Raja, Harish; Grube, Thomas J; Geraets, Ryan L; Johnston, Patrick B; O'Neill, Brian P; Pulido, Jose S

    2017-01-01

    To determine the occurrence of macular edema (ME) in vitreoretinal lymphoma (VRL). Retrospective analysis of 17 patients (31 eyes) with VRL. A review of the literature was done as well. Nine patients (15 eyes) had fluorescein angiography and/or optical coherence tomography at presentation. In the ME group (six eyes of four patients), three patients (five eyes) had prior chemotherapy and radiation. Excluding eyes with radiation retinopathy (three eyes), rate of ME was 25% (3/12). When two unirradiated fellow eyes of eyes with radiation retinopathy were also excluded, ME rate was 10% (1/10). Excluding the eyes with intraocular surgery, the rate of ME was 0%. In the group without ME (nine eyes of six patients), one patient (one eye) was treated with chemotherapy and radiation and three patients (five eyes) with chemotherapy. Review of the literature showed that the ME was found between 2 and 60% of cases, but most of the cases with ME had prior interventions. Macular edema in VRL is not uncommon but usually related to prior interventions. Macular edema as an initial presentation of VRL is rare.

  1. Enterobius vermicularis infestation of the appendix and management at the time of laparoscopic appendectomy: case series and literature review.

    Science.gov (United States)

    Ariyarathenam, A V; Nachimuthu, S; Tang, T Y; Courtney, E D; Harris, S A; Harris, A M

    2010-01-01

    Enterobius vermicularis infestation of the vermiform appendix can mimic appendicitis. In these cases, laparoscopic appendicectomy runs a risk of contamination of the peritoneal cavity with worms. We reviewed our practice to suggest changes that will reduce the release of worms and propose methods to use in case contamination occurs. 498 patients underwent appendicectomy over a sixty-three month period. 13 (2.6%) patients had confirmed E. vermicularis on histology of whom 6 (46%) were performed laparoscopically. These patients' case notes were retrospectively reviewed. The worms were noted intra-operatively during the laparoscopic appendectomies. In 2 cases, where peritoneal cavity contamination with worms occurred, they were dealt with careful diathermy or endoscopic suction. In the other cases, contamination was avoided by simple measures including division of the appendix in a staggered manner whilst maintaining traction, removal of worms using endoscopic suction or diathermy and quick transfer to a specimen bag. We highlight that the symptoms of appendicitis can be due to Enterobius vermicularis infestation without any histological evidence of acute inflammation. Surgeons need to be aware of this possibility during laparoscopic appendicectomy and simple techniques can minimise the risk of contamination. It also enables early diagnosis and treatment without awaiting histological findings. Copyright © 2010 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  2. Cardiac myosin binding protein-C as a central target of cardiac sarcomere signaling: a special mini-review series

    Science.gov (United States)

    de Tombe, Pieter P.

    2013-01-01

    Cardiac myosin binding protein-C (cMyBP-C) is a cardiac-specific thick filament assembly, accessory and regulatory protein. Physiologically, it is a key regulator of cardiac contractility. With more than two hundred mutations in the cMyBP-C gene directly linked to the development of cardiomyopathy and heart failure, cMyBP-C clearly plays a critical role in heart function. At baseline, cMyBP-C is highly phosphorylated, a condition required for normal cardiac function. However, the level of cMyBP-C phosphorylation is significantly decreased during heart failure, indicating that the level of cMyBP-C phosphorylation is directly linked to signaling and cardiac function. Early studies indicated that cMyBP-C interacts with myosin and titin, whereas studies now show that it also interacts with thin filament proteins. However, the exact role(s) of cMyBP-C in the heart remain(s) to be elucidated. As such, we invited experts in the field of cardiac muscle to identify and address key issues related to cMyBP-C by contributing a mini-review on such topics as structure, function, regulation, cardiomyopathy, proteolysis, and gene therapy. Starting from this issue, Pflügers Archiv European Journal of Physiology will publish two invited mini-review articles each month to discuss the most recent advances in the study of cMyBP-C. PMID:24196566

  3. Cardiac myosin binding protein-C as a central target of cardiac sarcomere signaling: a special mini review series.

    Science.gov (United States)

    Sadayappan, Sakthivel; de Tombe, Pieter P

    2014-02-01

    Cardiac myosin binding protein-C (cMyBP-C) is a cardiac-specific thick filament assembly, accessory, and regulatory protein. Physiologically, it is a key regulator of cardiac contractility. With more than 200 mutations in the cMyBP-C gene directly linked to the development of cardiomyopathy and heart failure, cMyBP-C clearly plays a critical role in heart function. At baseline, cMyBP-C is highly phosphorylated, a condition required for normal cardiac function. However, the level of cMyBP-C phosphorylation is significantly decreased during heart failure, indicating that the level of cMyBP-C phosphorylation is directly linked to signaling and cardiac function. Early studies indicated that cMyBP-C interacts with myosin and titin, whereas studies now show that it also interacts with thin filament proteins. However, the exact role(s) of cMyBP-C in the heart remain(s) to be elucidated. As such, we invited experts in the field of cardiac muscle to identify and address key issues related to cMyBP-C by contributing a mini review on such topics as structure, function, regulation, cardiomyopathy, proteolysis, and gene therapy. Starting from this issue, Pflügers Archiv European Journal of Physiology will publish two invited mini review articles each month to discuss the most recent advances in the study of cMyBP-C.

  4. Prosthetic rehabilitation of oral submucous fibrosis patients: A systematic review of published case reports and case series

    Science.gov (United States)

    Patil, Shankargouda; Sarode, Gargi S.; Bhandi, Shilpa; Awan, Kamran Habib; Ferrari, Marco

    2017-01-01

    Background Oral submucous fibrosis (OSF) is an insidious chronic condition characterized by restricted mouth opening. Prosthetic rehabilitation is challenging for OSF patients as obtaining a good impression requires adequate mouth opening. The aim of the present review is to systematically present the data from case reports published in the English-language literature. Method A comprehensive search of the literature databases (PubMed, Medline, SCOPUS, Web of Science and Google Scholar) along with the references of published articles on prosthetic rehabilitation in OSF patients published to date was conducted. Keywords included a combination of ‘Oral submucous fibrosis’, ‘prosthesis’, ‘dentures’ and/or ‘restricted mouth opening’. Citations from selected references and bibliographic linkages taken from similar cases were included in this review. The inclusion criteria selected for case reports on prosthetic rehabilitation in OSF patients, and cases of restricted mouth opening due to causes other than OSF were excluded from the study. Results A total of 21 cases were identified and analysed from 17 papers published in the English-language literature. Of these, 9 cases employed the sectional denture technique, 4 cases emphasized the need-based treatment approach in which conventional methods were modified, and 4 cases used mouth exercising devices. Finally, 1 case each involved, flexible denture, oral screen prosthesis, oral stents, surgery in conjunction with dentures. Conclusion Prosthetic rehabilitation in OSF patients is a multifaceted approach and should be patient specific, although sectional dentures have achieved the best results. PMID:28877246

  5. Severe accident mitigation strategy for the generation II PWRs in France. Some outcomes of the on-going periodic safety review of the French 1300 MWe PWR series

    Energy Technology Data Exchange (ETDEWEB)

    Cenerino, G.; Rahni, N.; Chevrier, P.; Dubreuil, M.; Guigueno, Y.; Raimond, E.; Bonnet, J.M. [IRSN/PSN-RES/SAG (France)

    2013-07-01

    The 3{sup rd} Periodic Safety Review of the French 1300 MWe PWRs series includes some modifications to increase their robustness in case of a severe accident. Their review is based on both deterministic and probabilistic approaches, keeping in mind that severe accidents frequencies and radiological consequences should be as low as reasonably practicable, severe accidents management strategies should be as safe as possible and the robustness of equipment used for severe accident management should be ensured. Consequently, the IRSN level 2 probabilistic safety assessment (L2 PSA) studies for the 1300 MWe reactors have been used to re-assess the results of the utility's L2 PSA and rank them to identify the containment failure modes contributing the most to the global risk. This ranking helped the review of plant modifications. Regarding strategies for accident management, the EDF management of water in the reactor cavity during a severe accident for the 1300 MWe PWRs is presented as well as the IRSN position on this strategy: this is an example where the optimal severe accident management strategy choice is not so easy to define. Regarding the robustness of equipment used for severe accident management, the interest of a diversification or redundancy of the French emergency filtered containment venting opening is one example among many others. (orig.)

  6. An empirically grounded framework to guide blogging for digital scholarship

    Directory of Open Access Journals (Sweden)

    Shailey Minocha

    2012-08-01

    Full Text Available This research project investigated how openness and sharing of knowledge are manifested through scholarly blogging. We aimed to identify the academics’ and researchers’ motivations for starting a blog; the contribution of blogging to their personal and professional development; and any challenges. Twenty-six participants were recruited. A pre-interview questionnaire was first emailed to the participants to collect background information. An initial unstructured interview was conducted by email, followed by a synchronous semi-structured interview. Textual and visual extracts of blog content were also collected. The datasets were analysed using different techniques. The findings revealed varied reasons for blogging. Some academics/researchers began a blog for its accessibility to self and others. Blogging aided the academics’ and researchers’ personal and professional development in several ways. Bloggers can quickly reach a wider audience compared to other forms of academic publishing. Among the challenges, there were concerns over validity of online content. Based on previous scholarship models and on our findings, we have derived an empirically grounded framework of blog use in academia and research. The framework describes how characteristics of digital scholarship such as openness and sharing are manifested through blogging. The framework can be used to guide academics and researchers who are interested in taking up blogging as a scholarly practice.

  7. A decade of adaptive governance scholarship: synthesis and future directions

    Directory of Open Access Journals (Sweden)

    Brian C. Chaffin

    2014-09-01

    Full Text Available Adaptive governance is an emergent form of environmental governance that is increasingly called upon by scholars and practitioners to coordinate resource management regimes in the face of the complexity and uncertainty associated with rapid environmental change. Although the term "adaptive governance" is not exclusively applied to the governance of social-ecological systems, related research represents a significant outgrowth of literature on resilience, social-ecological systems, and environmental governance. We present a chronology of major scholarship on adaptive governance, synthesizing efforts to define the concept and identifying the array of governance concepts associated with transformation toward adaptive governance. Based on this synthesis, we define adaptive governance as a range of interactions between actors, networks, organizations, and institutions emerging in pursuit of a desired state for social-ecological systems. In addition, we identify and discuss ambiguities in adaptive governance scholarship such as the roles of adaptive management, crisis, and a desired state for governance of social-ecological systems. Finally, we outline a research agenda to examine whether an adaptive governance approach can become institutionalized under current legal frameworks and political contexts. We suggest a further investigation of the relationship between adaptive governance and the principles of good governance; the roles of power and politics in the emergence of adaptive governance; and potential interventions such as legal reform that may catalyze or enhance governance adaptations or transformation toward adaptive governance.

  8. Towards supporting scholarship in research by clinical pharmacy faculty.

    Science.gov (United States)

    Pickard, A Simon

    2006-10-01

    The objective of this study was to assess the need for research support, faculty development, and topics of interest to clinical track pharmacy faculty that would facilitate scholarship in research. A cross-sectional survey of pharmacy practice-based faculty at University of Illinois at Chicago (UIC) completed via the web in November 2005. Of 39 clinical track faculty respondents (48% response rate), 100% indicated they were interested in being co-investigator or 77% lead investigator on a research grant proposal. The majority of respondents expressed "a lot" or "extreme" interest in receiving methodological guidance and administrative support in order to pursue research interests. The greatest interest in research support services related to sample size calculations, selection of appropriate statistical tests, grant writing, and writing for journals. Barriers to research cited by faculty included lack of confidence in ability, the need for balancing responsibilities, and reward for efforts. Suggestions included the creation of specific research interest groups, research seminars, formal mentoring and statistical support services. Clinical-track faculty are interested in research-related scholarship but typically lack the confidence or skills to lead research. While this study was limited to UIC clinical faculty, UIC faculty are attracted from Colleges of Pharmacy across North America and it is notable that such barriers can be quickly identified using a brief web-based survey in order to inform a plan that provides resources and support for research by clinical pharmacy faculty.

  9. Towards supporting scholarship in research by clinical pharmacy faculty

    Directory of Open Access Journals (Sweden)

    Pickard AS

    2006-12-01

    Full Text Available Objective: The objective of this study was to assess the need for research support, faculty development, and topics of interest to clinical track pharmacy faculty that would facilitate scholarship in research.Methods: A cross-sectional survey of pharmacy practice-based faculty at University of Illinois at Chicago (UIC completed via the web in November 2005.Results: Of 39 clinical track faculty respondents (48% response rate, 100% indicated they were interested in being co-investigator or 77% lead investigator on a research grant proposal. The majority of respondents expressed “a lot” or “extreme” interest in receiving methodological guidance and administrative support in order to pursue research interests. The greatest interest in research support services related to sample size calculations, selection of appropriate statistical tests, grant writing, and writing for journals. Barriers to research cited by faculty included lack of confidence in ability, the need for balancing responsibilities, and reward for efforts. Suggestions included the creation of specific research interest groups, research seminars, formal mentoring and statistical support services.Conclusions: Clinical-track faculty are interested in research-related scholarship but typically lack the confidence or skills to lead research. While this study was limited to UIC clinical faculty, UIC faculty are attracted from Colleges of Pharmacy across North America and it is notable that such barriers can be quickly identified using a brief web-based survey in order to inform a plan that provides resources and support for research by clinical pharmacy faculty.

  10. Scholarships for scientific initiation encourage post-graduation degree.

    Science.gov (United States)

    Pinto, Gabriela S; Nascimento, Gustavo G; Mendes, Matheus S; Ogliari, Fabrício A; Demarco, Flávio F; Correa, Marcos B

    2014-01-01

    This study aimed to evaluate the factors associated with the decision to attend an academic post-graduation program by dental students. A cross-sectional study was conducted in 2012, last-year undergraduate students from Dental Schools of Southern Brazil. A closed questionnaire was applied including questions grouped in three different blocks: pre-graduate, undergraduate period and future perspectives. The outcome was the decision to pursuit an academic post-graduation degree. Associations were tested using chi-squared test and chi-squared test for linear trends when appropriate. Multivariate Poisson regression was also performed. The sample was composed by 671 students (response rate of 69.9%, n=467). In relation to future perspectives, 68% of the interviewed students intended to attend a post-graduation program, but only 17.5% would choose a program with academic and research post-graduation program (Master and PhD programs). In the final model, students from public universities (PR 2.08, 95%CI 1.41-3.08) and students that received scientific initiation scholarship (PR 1.93 95%CI 1.14-3.27) presented a twice greater prevalence to seek academic post-graduate programs. Students with higher family incomes showed a lower prevalence to seek these programs (PR 0.50, 95%IC 0.28-0.90). Scholarships seem to encourage undergraduate students to pursue stricto sensu post-graduation.

  11. Failed Surgical Management of Acute Proximal Fifth Metatarsal (Jones) Fractures: A Retrospective Case Series and Literature Review.

    Science.gov (United States)

    Granata, Jaymes D; Berlet, Gregory C; Philbin, Terrence M; Jones, Grant; Kaeding, Christopher C; Peterson, Kyle S

    2015-12-01

    Nonunion, delayed union, and refracture after operative treatment of acute proximal fifth metatarsal fractures in athletes is uncommon. This study was a failure analysis of operatively managed acute proximal fifth metatarsal fractures in healthy athletes. We identified 149 patients who underwent operative treatment for fifth metatarsal fractures. Inclusion criteria isolated skeletally mature, athletic patients under the age of 40 with a minimum of 1-year follow-up. Patients were excluded with tuberosity fractures, fractures distal to the proximal metaphyseal-diaphyseal region of the fifth metatarsal, multiple fractures or operative procedures, fractures initially treated conservatively, and medical comorbidities/risk factors for nonunion. Fifty-five patients met the inclusion/exclusion criteria. Four (7.3%) patients required a secondary operative procedure due to refracture. The average time to refracture was 8 months. All refractures were associated with bent screws and occurred in male patients who participated in professional basketball, professional volleyball, and college football. The average time for release to progressive weight-bearing was 6 weeks. Three patients were revised to a bigger size screw and went on to union. One patient was revised to the same-sized screw and required a second revision surgery for nonunion. All failures were refractures in competitive athletes who were initially treated with small diameter solid or cannulated stainless steel screws. The failures were not associated with early postoperative weight-bearing protocol. Maximizing initial fixation stiffness may decrease the late failure rate in competitive athletes. More clinical studies are needed to better understand risk factors for failure after screw fixation in the competitive, athletic population. Prognostic, Level IV: Case series. © 2015 The Author(s).

  12. Trauma to the hyoid bone and laryngeal cartilages in hanging: review of forensic research series since 1856.

    Science.gov (United States)

    Khokhlov, Vladislav D

    2015-01-01

    Since 1856 lots of forensic reports, concerning trauma to the hyoid bone and laryngeal cartilages in hanging, have been published. Differences in percentage of injured neck complexes ranged from 0 to 83.3%. Simple arguments suggest that the reason for discrepancy is difference in scientific approach (retro- or prospective) and use of various research methods. Comparative analysis of widely used techniques shows considerable variety in their effectiveness. Plain radiography and palpatory method have fairly low sensitivity (33-60% for different elements of the neck complex) with relatively high specificity (89-98.5%). Reported sensitivity of postmortem CT in identification of different lesions (including fractures) in trauma victims for the head/neck region is higher than 53% in different series with possible false-positive findings. In clinical setting the whole-body CT (pan-scanning) in blunt trauma patients showed sensitivity for head and neck injuries at the level of 84.6%, and specificity - 98.9% (Stengel et al., 2012 [68]). Only complete preparation allows to identify all the damages to the laryngopharynx framework, to avoid false diagnostics and ascertain the exact location, morphology, mechanism and intravital nature of the neck trauma. Currently complete preparation can be regarded as the method of "gold standard". Use of this method shows the frequency of discovered injuries in hanging to be about 70% of cases. In practical use, one should consider radiological techniques and palpation as preliminary and orienting methods (rather excluding, than revealing anterior neck trauma). Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. Minor salivary gland mucoepidermoid carcinoma in children and adolescents: a case series and review of the literature

    Directory of Open Access Journals (Sweden)

    Ritwik Priyanshi

    2012-07-01

    Full Text Available Abstract Introduction Because well-documented cases of mucoepidermoid carcinomas that are of minor salivary gland origin and occur in children and adolescents have rarely been reported, little information regarding their clinical features and biologic behavior is available. This case report represents a retrospective clinical analysis of five minor salivary gland mucoepidermoid carcinomas accessioned from a 35-year period at the Louisiana State University School of Dentistry and combines the data with 15 well-documented cases from the English language literature. Case presentation The five mucoepidermoid carcinomas in patients from birth to 19 years of age accounted for 1.3% of the accessioned minor salivary gland neoplasms. There were an additional 15 well-documented cases in the literature. Combining the data for the 20 mucoepidermoid carcinomas resulted in a mean age of 13.5 years and a 2.3:1 female-to-male ratio. Collectively, the hard palate, soft palate, and hard palate/soft palate junction accounted for 85% of the cases. Thirty-five percent of the cases presented as a fluctuant submucosal swelling with surface color alterations. The average duration was five months, and bone involvement occurred in seven cases. A histologic grade of low to intermediate predominated (95%. Surgical removal was the treatment in all cases. Thirteen cases had adequate follow-up of three years or more, and recurrence was documented in only one case. There were no cases of death or metastasis in this series. Conclusions In children and adolescents, mucoepidermoid carcinomas have a female predilection and occur most commonly on the hard or soft palate or both. A fluctuant submucosal lump with a bluish color is a helpful diagnostic clue. The histologic grades of most mucoepidermoid carcinomas in the first and second decades of life are low and, to a lesser degree, intermediate. Complete surgical excision is the treatment of choice and results in a recurrence

  14. Novel Treatment of Radicular Pain With a Multi-Mechanistic Combination Topical Agent: A Case Series and Literature Review.

    Science.gov (United States)

    Safaeian, Pegah; Mattie, Ryan; Hahn, Matthew; Plastaras, Christopher T; McCormick, Zachary L

    2016-04-01

    Pharmacologic treatment of radicular pain with oral medications is limited by adverse effects and concern for dependence. While topical formulations have been explored in pain research, there is no published literature evaluating the efficacy in radicular pain. We present the first three cases of radicular pain successfully treated with a topical formulation of diclofenac, ibuprofen, baclofen, cyclobenzaprine, bupivacaine, gabapentin, and pentoxifylline (T7). Case series evaluating T7 for treatment of radicular pain in a single, outpatient pain center. Pain was rated on the numeric rating scale (NRS) on initial evaluation and follow up after a trial of T7. One to two grams of T7 was applied to the affected area 3 - 4 times daily in addition to the patient's baseline pharmacologic management. Three patients with median age of 50 (range, 39 to 65) and diagnosis of cervical and/or lumbosacral radicular pain participated. Two of the three had chronic radicular pain despite use of analgesic agents, spinal injections and failed spinal surgery syndrome. Each reported subjective improvement in radicular pain, function and sleep. There was an average decrease in NRS score consistent with 30% - 40% global improvement in symptoms, clinically significant based on the minimal clinically important difference for radicular pain. T7 was well tolerated without adverse reactions. Surgery was prevented or delayed in all cases. This is the first report of the successful treatment of radicular pain with a topical agent. This highlights the need for randomized, prospective study of both single and compounded topical agents for treatment of radicular pain.

  15. ScholarshipBuilder Program, Second Annual Report 1989-1990. Report No. 10, Vol. 25.

    Science.gov (United States)

    Ruffin, Minnie R.; And Others

    The ScholarshipBuilder Program, an adopt-a-class program, began in November 1988 to encourage selected first-grade students to stay in school until graduation in the year 2000. Scholarships will be provided by Merrill Lynch, Incorporated, for students who go on to college, and a one-time stipend will be provided to students who enter the military…

  16. Cost Study of the Saint Paul Early Childhood Scholarship Program. Technical Report

    Science.gov (United States)

    Schwartz, Heather L.; Karoly, Lynn A.

    2011-01-01

    In 2008, the Minnesota Early Learning Foundation created the Saint Paul Early Childhood Scholarship Program, a pilot program to provide families with scholarships to cover the cost of high-quality early childhood education (ECE) programs. Although there is a large body of research about the benefits of preschool specifically and early learning…

  17. The Achievement Checkup: Tracking the Post-Elementary Outcomes of Baltimore Need-Based Scholarship Students

    Science.gov (United States)

    Schuh, Alex

    2015-01-01

    This study examined the high school experiences, graduation rates and post-secondary attendance rates of students who received need-based scholarships to attend private elementary schools from the Children's Scholarship Fund Baltimore (CSFB). CSFB provides funds to students from low-income families in the Baltimore area to attend the private or…

  18. "Civil Religion" and Confucianism : Japan's Past, China's Present, and the Current Boom in Scholarship on Confucianism

    NARCIS (Netherlands)

    Paramore, K.N.

    2016-01-01

    This article employs the history of Confucianism in modern Japan to critique current scholarship on the resurgence of Confucianism in contemporary China. It argues that current scholarship employs modernist formulations of Confucianism that originated in Japan’s twentieth-century confrontation with

  19. Leveraging New Media in the Scholarship of Engagement: Opportunities and Incentives

    Science.gov (United States)

    LaBelle, Chris; Anderson-Wilk, Mark; Emanuel, Robert

    2011-01-01

    This article looks at how Extension faculty and administrators perceive digital scholarship in relation to their institutions' reward systems. Our survey data suggest that even when land-grant institutions have policies in place to reward alternative or new forms of scholarship, these policies are often unclear or inaccessible, are not reflected…

  20. Finding Time for Scholarship: A Survey of Canadian Research University Librarians

    Science.gov (United States)

    Fox, David

    2007-01-01

    More than half the participants in a survey of Canadian research university librarians indicated that scholarship activities were required or encouraged at their universities, yet most university librarians have year-round schedules of assigned duties that present challenges to the engagement in sustained, meaningful scholarship. Full-time…