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Sample records for scandium 61

  1. Scandium recovery from slags after oxidized nickel ore processing

    Science.gov (United States)

    Smyshlyaev, Denis; Botalov, Maxim; Bunkov, Grigory; Rychkov, Vladimir; Kirillov, Evgeny; Kirillov, Sergey; Semenishchev, Vladimir

    2017-09-01

    One of the possible sources of scandium production - waste (slags) from processing of oxidized nickel ores, has been considered in present research work. The hydrometallurgical method has been selected as the primary for scandium extraction. Different reagents for leaching of scandium, such as sulfuric acid, various carbonate salts and fluorides, have been tested. Sulfuric acid has been recognized as an optimal leaching reagent. Sulfuric acid concentration of 100 g L-1 allowed recovering up to 97 % of scandium.

  2. Influence of scandium concentration on power generation figure of merit of scandium aluminum nitride thin films

    Energy Technology Data Exchange (ETDEWEB)

    Akiyama, Morito; Nagase, Toshimi [Measurement Solution Research Center, National Institute of Advanced Industrials Science and Technology, Tosu, Saga 841-0052 (Japan); Umeda, Keiichi; Honda, Atsushi [Murata Manufacturing Co., Ltd., Nagaokakyo, Kyoto 617-8555 (Japan)

    2013-01-14

    The authors have investigated the influence of scandium concentration on the power generation figure of merit (FOM) of scandium aluminum nitride (Sc{sub x}Al{sub 1-x}N) films prepared by cosputtering. The power generation FOM strongly depends on the scandium concentration. The FOM of Sc{sub 0.41}Al{sub 0.59}N film was 67 GPa, indicating that the FOM is five times larger than that of AlN. The FOM of Sc{sub 0.41}Al{sub 0.59}N film is higher than those of lead zirconate titanate and Pb(Mg{sub 1/3}Nb{sub 2/3})O{sub 3}-PbTiO{sub 3} films, which is the highest reported for any piezoelectric thin films. The high FOM of Sc{sub 0.41}Al{sub 0.59}N film is due to the high d{sub 31} and the low relative permittivity.

  3. Lifetime measurements and oscillator strengths in singly ionized scandium and the solar abundance of scandium

    Science.gov (United States)

    Pehlivan Rhodin, A.; Belmonte, M. T.; Engström, L.; Lundberg, H.; Nilsson, H.; Hartman, H.; Pickering, J. C.; Clear, C.; Quinet, P.; Fivet, V.; Palmeri, P.

    2017-12-01

    The lifetimes of 17 even-parity levels (3d5s, 3d4d, 3d6s and 4p2) in the region 57 743-77 837 cm-1 of singly ionized scandium (Sc II) were measured by two-step time-resolved laser induced fluorescence spectroscopy. Oscillator strengths of 57 lines from these highly excited upper levels were derived using a hollow cathode discharge lamp and a Fourier transform spectrometer. In addition, Hartree-Fock calculations where both the main relativistic and core-polarization effects were taken into account were carried out for both low- and high-excitation levels. There is a good agreement for most of the lines between our calculated branching fractions and the measurements of Lawler & Dakin in the region 9000-45 000 cm-1 for low excitation levels and with our measurements for high excitation levels in the region 23 500-63 100 cm-1. This, in turn, allowed us to combine the calculated branching fractions with the available experimental lifetimes to determine semi-empirical oscillator strengths for a set of 380 E1 transitions in Sc II. These oscillator strengths include the weak lines that were used previously to derive the solar abundance of scandium. The solar abundance of scandium is now estimated to logε⊙ = 3.04 ± 0.13 using these semi-empirical oscillator strengths to shift the values determined by Scott et al. The new estimated abundance value is in agreement with the meteoritic value (logεmet = 3.05 ± 0.02) of Lodders, Palme & Gail.

  4. Smelting of Scandium by Microwave Irradiation.

    Science.gov (United States)

    Fujii, Satoshi; Tsubaki, Shuntaro; Inazu, Naomi; Suzuki, Eiichi; Wada, Yuji

    2017-09-27

    Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices-including acoustic ones-because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF₃ through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  5. Smelting of Scandium by Microwave Irradiation

    Directory of Open Access Journals (Sweden)

    Satoshi Fujii

    2017-09-01

    Full Text Available Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices—including acoustic ones—because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF3 through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  6. Hydrometallurgical methods of recovery of scandium from the wastes of various technologies

    Science.gov (United States)

    Molchanova, T. V.; Akimova, I. D.; Smirnov, K. M.; Krylova, O. K.; Zharova, E. V.

    2017-03-01

    The recovery of scandium from the wastes of the production of uranium, titanium, iron-vanadium, and alumina is studied. The applied acid schemes of scandium transfer to a solution followed by ion-exchange recovery and extraction concentration of scandium ensure the precipitation of crude scandium oxides containing up to 5% Sc2O3. Scandium oxides of 99.96-99.99% purity are formed after additional refining of these crude oxides according to an extraction technology using a mixture 15% multiradical phosphine oxide or Cyanex-925 + 15% tributyl phosphate in kerosene.

  7. Synthesis and Reactivity of a Scandium Terminal Hydride: H2  Activation by a Scandium Terminal Imido Complex.

    Science.gov (United States)

    Han, Xianghao; Xiang, Li; Lamsfus, Carlos A; Mao, Weiqing; Lu, Erli; Maron, Laurent; Leng, Xuebing; Chen, Yaofeng

    2017-10-20

    Dihydrogen is easily activated by a scandium terminal imido complex containing the weakly coordinated THF. The reaction proceeds through a 1,2-addition mechanism, which is distinct from the σ-bond metathesis mechanism reported to date for rare-earth metal-mediated H2 activation. This reaction yields a scandium terminal hydride, which is structurally well-characterized, being the first one to date. The reactivity of this hydride is reported with unsaturated substrates, further shedding light on the existence of the terminal hydride complex. Interestingly, the H2 activation can be reversible. DFT investigations further eludciate the mechanistic aspects of the reactivity of the scandium anilido-terminal hydride complex with PhNCS but also on the reversible H2 activation process. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Thermoelectric material comprising scandium doped zinc cadmium oxide

    DEFF Research Database (Denmark)

    2016-01-01

    There is presented a composition of scandium doped Zinc Cadmium Oxide with the general formula ZnzCdxScyO which the inventors have prepared, and for which material the inventors have made the insight that it is particularly advantageous as an n-type oxide material, such as particularly advantageous...

  9. Scandium/carbon filters for soft x rays

    NARCIS (Netherlands)

    Artioukov, IA; Kasyanov, YS; Kopylets, IA; Pershin, YP; Romanova, SA

    2003-01-01

    This Note deals with thin-film soft x-ray filters for operation at the wavelengths near carbon K edge (similar to4.5 nm). The filters were fabricated by magnetron sputtering deposition of thin layers of scandium (total thickness 0.1-0.2 mum) onto films of polypropylene (thickness 1.5 mum) and

  10. Solvent extraction of scandium from lateritic nickel- cobalt ores using different organic reagents

    OpenAIRE

    Ferizoğlu Ece; Kaya Şerif; Topkaya Yavuz A.

    2016-01-01

    Scandium is the most important and strategic metal that can be recovered as a by-product from lateritic nickel-cobalt ores. In this research, different extractants were investigated in order to extract scandium from a sulfate medium by a using a solvent extraction method. Generally, the organic extractants are classified as acidic, neutral and basic organophosphorus compounds. However, in solvent extraction of scandium, the acidic and neutral organophosphorus compounds are preferred due to th...

  11. BASIC RESEARCH ON THE SEPARATION OF SCANDIUM YTTRIUM, AND THE RARE EARTHS BY SOLVENT EXTRACTION.

    Science.gov (United States)

    RARE EARTH ELEMENTS, * SOLVENT EXTRACTION ), (*CHELATE COMPOUNDS, RARE EARTH ELEMENTS), PURIFICATION, ATOMIC SPECTROSCOPY, SCANDIUM, YTTRIUM, PRASEODYMIUM, SAMARIUM, EUROPIUM, GADOLINIUM, TERBIUM, FLUORINE COMPOUNDS, KETONES

  12. Determination of scandium concentrate composition by WD-XRF and ICP-MS methods

    Science.gov (United States)

    Sarkisova, A. S.; Shibitko, A. O.; Abramov, A. V.; Rebrin, O. I.; Bunkov, G. M.; Lisienko, D. G.

    2017-09-01

    WD-XRF spectroscopy was applied for determining composition of scandium concentrate (ScC) containing 70 % scandium fluoride. Determination of ScC composition was performed using 6 glass beads reference materials produced by fusing synthesized mixture of analyte compounds with the lithium-borate flux in the ratio of 1:10. ScC powder with the known composition was then used as a powder pellet reference material to analyze scandium concentrate from technological line by external standard method. ICP-MS method was employed to control the ScC composition. The statistical data processing and metrological parameters evaluation of the analytical technique developed were carried out.

  13. Tin etching from metallic and oxidized scandium thin films

    Science.gov (United States)

    Pachecka, M.; Lee, C. J.; Sturm, J. M.; Bijkerk, F.

    2017-08-01

    The role of oxide on Sn adhesion to Sc surfaces was studied with in-situ ellipsometry, X-ray photoelectron spectroscopy and secondary electron microscopy. Sn etching with hydrogen radicals was performed on metallic Sc, metallic Sc with a native oxide, and a fully oxidized Sc layer. The results show that Sn adsorbs rather weakly to a non-oxidized Sc surface, and is etched relatively easily by atomic hydrogen. In contrast, the presence of native oxide on Sc allows Sn to adsorb more strongly to the surface, slowing the etching. Furthermore, thinner layers of scandium oxide result in weaker Sn adsorption, indicating that the layer beneath the oxide plays a significant role in determining the adsorption strength. Unexpectedly, for Sn on Sc2O3, and, to a lesser extent, for Sn on Sc, the etch rate shows a variation over time, which is explained by surface restructuring, temperature change, and hydrogen adsorption saturation.

  14. Tin etching from metallic and oxidized scandium thin films

    Directory of Open Access Journals (Sweden)

    M. Pachecka

    2017-08-01

    Full Text Available The role of oxide on Sn adhesion to Sc surfaces was studied with in-situ ellipsometry, X-ray photoelectron spectroscopy and secondary electron microscopy. Sn etching with hydrogen radicals was performed on metallic Sc, metallic Sc with a native oxide, and a fully oxidized Sc layer. The results show that Sn adsorbs rather weakly to a non-oxidized Sc surface, and is etched relatively easily by atomic hydrogen. In contrast, the presence of native oxide on Sc allows Sn to adsorb more strongly to the surface, slowing the etching. Furthermore, thinner layers of scandium oxide result in weaker Sn adsorption, indicating that the layer beneath the oxide plays a significant role in determining the adsorption strength. Unexpectedly, for Sn on Sc2O3, and, to a lesser extent, for Sn on Sc, the etch rate shows a variation over time, which is explained by surface restructuring, temperature change, and hydrogen adsorption saturation.

  15. Extraction of scandium by liquid di-2-ethylhexylphosphoric acid in fusible diluents

    Directory of Open Access Journals (Sweden)

    Ainur Isatayeva

    2015-03-01

    Full Text Available Currently widespread distribution of extraction methods using fusible reagents can be explained by a number of advantages, such as high kinetic characteristics of the process, the ease separation of two phases, high selectivity of many extractants, relatively complete regeneration. For the extraction of scandium in technological order, neutral and cation exchange extractants can be used. Several extraction reagents melt easily at high temperatures, and such melts can be used for extraction. Efficiency of the extraction of metal by cation reagents depends on many factors. Extraction of scandium by melt mixtures of di-2-ethylhexylphosphoric acid - higher carboxylic acid - paraffin and the effect of acidity of the aqueous phase, the concentration of scandium and the aqueous extractant in the organic phase, the volume ratio of organic and aqueous phases on the extraction of metal were studied. It was found that the extraction of scandium proceeds through the cation exchange mechanism. Scandium was extracted quantitatively (> 99.0% from acid solutions. The optimal concentration of di-2-ethylhexylphosphoric acid in the extractant was 0,250 M, quantitative extraction of scandium was observed in the range of its concentrations of 10-3-10-6 M and the volume ratio of organic phases to aqueous phases of 1:5 - 1:20.

  16. Thermodynamic and kinetic study of scandium(III) complexes of DTPA and DOTA: a step toward scandium radiopharmaceuticals.

    Science.gov (United States)

    Pniok, Miroslav; Kubíček, Vojtěch; Havlíčková, Jana; Kotek, Jan; Sabatie-Gogová, Andrea; Plutnar, Jan; Huclier-Markai, Sandrine; Hermann, Petr

    2014-06-23

    Diethylenetriamine-N,N,N',N'',N''-pentaacetic acid (DTPA) and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) scandium(III) complexes were investigated in the solution and solid state. Three (45)Sc NMR spectroscopic references suitable for aqueous solutions were suggested: 0.1 M Sc(ClO4)3 in 1 M aq. HClO4 (δSc =0.0 ppm), 0.1 M ScCl3 in 1 M aq. HCl (δSc =1.75 ppm) and 0.01 M [Sc(ox)4](5-) (ox(2-) = oxalato) in 1 M aq. K2C2O4 (δSc =8.31 ppm). In solution, [Sc(dtpa)](2-) complex (δSc = 83 ppm, Δν = 770 Hz) has a rather symmetric ligand field unlike highly unsymmetrical donor atom arrangement in [Sc(dota)](-) anion (δSc = 100 ppm, Δν = 4300 Hz). The solid-state structure of K8[Sc2(ox)7]⋅13 H2O contains two [Sc(ox)3](3-) units bridged by twice "side-on" coordinated oxalate anion with Sc(3+) ion in a dodecahedral O8 arrangement. Structures of [Sc(dtpa)](2-) and [Sc(dota)](-) in [(Hguanidine)]2[Sc(dtpa)]⋅3 H2O and K[Sc(dota)][H6 dota]Cl2⋅4 H2O, respectively, are analogous to those of trivalent lanthanide complexes with the same ligands. The [Sc(dota)](-) unit exhibits twisted square-antiprismatic arrangement without an axial ligand (TSA' isomer) and [Sc(dota)](-) and (H6 dota)(2+) units are bridged by a K(+) cation. A surprisingly high value of the last DOTA dissociation constant (pKa =12.9) was determined by potentiometry and confirmed by using NMR spectroscopy. Stability constants of scandium(III) complexes (log KScL 27.43 and 30.79 for DTPA and DOTA, respectively) were determined from potentiometric and (45)Sc NMR spectroscopic data. Both complexes are fully formed even below pH 2. Complexation of DOTA with the Sc(3+) ion is much faster than with trivalent lanthanides. Proton-assisted decomplexation of the [Sc(dota)](-) complex (τ1/2 =45 h; 1 M aq. HCl, 25 °C) is much slower than that for [Ln(dota)](-) complexes. Therefore, DOTA and its derivatives seem to be very suitable ligands for scandium

  17. Effects of iron on intermetallic compound formation in scandium modified Al–Si–Mg Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [National Metal and Materials Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@mail.kmutt.ac.th [Production Engineering Department, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2014-12-15

    Highlights: • Iron reduces the modification effects of scandium in Al–Si–Mg alloys. • Morphologies of Sc-rich intermetallic phases vary with Fe and Sc contents and the cooling rates. • Sc neutralizes effects of Fe by changing Fe-rich intermetallic phases from platelets to more cubic. - Abstract: In general, iron has a strong tendency to dissolve in molten aluminum. Iron has very low solid solubility in aluminum–silicon casting alloys, so it will form intermetallic compounds that cause detrimental effects on mechanical properties. In this work, the effects of iron on intermetallic compound formations in scandium modified Al–Si–Mg alloys were studied. There were two levels of iron addition (0.2 and 0.4 wt.%) and two levels of scandium addition (0.2 and 0.4 wt.%). We found that the effects of scandium modification decreased with increasing iron addition. The morphologies of the complex intermetallic compounds were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and electron backscatter diffraction (EBSD) techniques. It was found that scandium changes the morphology of Fe-rich intermetallic compounds from β-phase (plate-like) to α-phase, which reduces the harmful effects of β-phase.

  18. Solvent extraction of scandium from lateritic nickel- cobalt ores using different organic reagents

    Directory of Open Access Journals (Sweden)

    Ferizoğlu Ece

    2016-01-01

    Full Text Available Scandium is the most important and strategic metal that can be recovered as a by-product from lateritic nickel-cobalt ores. In this research, different extractants were investigated in order to extract scandium from a sulfate medium by a using a solvent extraction method. Generally, the organic extractants are classified as acidic, neutral and basic organophosphorus compounds. However, in solvent extraction of scandium, the acidic and neutral organophosphorus compounds are preferred due to their higher extraction efficiencies. Thus, the aim of the present study was to compare the scandium extraction efficiencies of some acidic and neutral organic reagents. For this reason, Ionquest 290 (Bis(2,4,4-trimethylpenthyl phosphonic acid, DEHPA (Di(2-ethylhexyl phosphoric acid, Cyanex 272 ((Bis(2,4,4-trimethylpentyl phosphinic acid which are acidic organophosphorus compounds, and Cyanex 923 (Trialkylphosphine oxide, which is a neutral organophosphorus compound, were used. The extraction capacities of these organics were studied with respect to the extractant concentration at same pH and phase ratio. As a result of the study, DEHPA was found to have higher scandium extraction efficiency with lower iron extraction at pH = 0.55 at a phase ratio of 10:1 = A:O.

  19. Correlation between stoichiometry and properties of scandium oxide films prepared by reactive magnetron sputtering

    Science.gov (United States)

    Belosludtsev, Alexandr; Juškevičius, Kęstutis; Ceizaris, Lukas; Samuilovas, Romanas; Stanionytė, Sandra; Jasulaitienė, Vitalija; Kičas, Simonas

    2018-01-01

    Scandium oxide films were deposited on fused silica substrates by reactive pulsed DC magnetron sputtering. The use of feed-back optical emission monitoring enabled high-rate reactive deposition of films with tunable stoichiometry and properties. The under-stoichiometric, stoichiometric and over-stoichiometric scandium oxide films were prepared. The compressive stress in films was between 235 and 530 MPa. We showed that phase structure, density, surface roughness and optical properties of the scandium oxide are affected by the film stoichiometry and deposition conditions. Transparent scandium oxide films were slightly hydrophobic (94 ± 3°), homogeneous with a crystallite size of 20 ± 5 nm. The lowest extinction coefficient 0.7 × 10-3, the highest refractive index 2.08 (both quantities at the wavelength of 355 nm) and the highest density 4.1 ± 0.1 g cm-3 exhibited film prepared with the stoichiometric composition. Stoichiometric scandium oxide can be used in various optical applications as high refractive index and wide bandgap material. Transitions to under- or over-stoichiometry lead to a decrease of film density, refractive index and increase of the extinction coefficient.

  20. Mossbauer investigation of scandium oxide-hematite nanoparticles

    Science.gov (United States)

    Allwes, Mark; Sorescu, Monica

    Scandium oxide-doped hematite, xSc2O3*(1-x)alpha-Fe2O3 with molar concentration x =0.1, 0.3, and 0.5 was prepared by using ball milling, taking samples at times 0, 2, 4, 8, and 12 hours. The resulting Mossbauer spectra of the nanoparticles systems were parameterized using NORMOS-90. For each concentration, the spectra at 0 hours only consisted of 1 sextet, as the substitution of Sc2O3into Fe2O3 did not appear until after 2 hours of ball milling time (BMT). Concentration x =0.1 at BMT 2hours consisted of 2 sextets while x =0.3 and 0.5 were fit with 1 sextet and 1 quadrupole-split doublet. Concentration x =0.1 at BMT 4 and 8 hours consisted of 3 sextets, and at BMT 12 hours consisted of 4 sextets. For concentrations x =0.3 and 0.5 at BMT 4, 8, and 12 hours the spectra were fit with 3 sextets and 1 quadrupole-split doublet. With increasing initial concentration, the appearance of the quadrupole-split doublet became more pronounced, indicating the substitution of Fe into Sc2O3 occurred. But for x =0.1, the BMT did influence the number of sextets needed, causing an increase in substitution of Sc2O3 into Fe2O3.

  1. Association between toenail scandium levels and risk of acute myocardial infarction in European men: The EURAMIC and Heavy Metals Study

    NARCIS (Netherlands)

    Gómez-Aracena, J.; Martin-Moreno, J.M.; Riemersma, R.A.; Bode, P.; Gutiérrez-Bedmar, M.; Gorgojo, L.; Kark, J.D.; Garcia-Rodríguez, A.; Gomez-Gracia, E.; Kardinaal, A.F.M.; Aro, A.; Veer, P. van 't; Wedel, H.; Kok, F.J.; Fernández-Crehuet, J.

    2002-01-01

    The association between scandium status and risk of acute myocardial infarction (MI) was examined in a multicentre case control study in 10 centres from Europe and Israel. Scandium in toenails was assessed in 684 cases and 724 controls less than 70 years of age. Mean concentrations of toenail

  2. In-source laser spectroscopy developments at TRILIS-towards spectroscopy on actinium and scandium

    Energy Technology Data Exchange (ETDEWEB)

    Raeder, Sebastian, E-mail: raeder@triumf.ca; Dombsky, Marik; Heggen, Henning; Lassen, Jens; Quenzel, Thomas [TRIUMF, Canada' s National Laboratory for Nuclear and Particle Physics (Canada); Sjoedin, Marica [GANIL (France); Teigelhoefer, Andrea [TRIUMF, Canada' s National Laboratory for Nuclear and Particle Physics (Canada); Wendt, Klaus [Johannes Gutenberg-Universitaet Mainz, Institut fuer Physik (Germany)

    2013-04-15

    Resonance Ionization Laser Ion Sources (RILIS) have become a versatile tool for production and study of exotic nuclides at Isotope Separator On-Line (ISOL) facilities such as ISAC at TRIUMF. The recent development and addition of a grating tuned spectroscopy laser to the TRIUMF RILIS solid state laser system allows for wide range spectral scans to investigate atomic structures on short lived isotopes, e.g., those from the element actinium, produced in uranium targets at ISAC. In addition, development of new and improved laser ionization schemes for rare isotope production at ISAC is ongoing. Here spectroscopic studies on bound states, Rydberg states and autoionizing (AI) resonances on scandium using the existing off-line capabilities are reported. These results allowed to identify a suitable ionization scheme for scandium via excitation into an autoionizing state at 58,104 cm{sup - 1} which has subsequently been used for ionization of on-line produced exotic scandium isotopes.

  3. Process and Mechanical Properties: Applicability of a Scandium modified Al-alloy for Laser Additive Manufacturing

    Science.gov (United States)

    Schmidtke, K.; Palm, F.; Hawkins, A.; Emmelmann, C.

    The applicability of an aluminium alloy containing scandium for laser additive manufacturing (LAM) is considered. Modified aluminium alloys with a scandium content beyond the eutectic point offer great potential to become a high prioritized aerospace material. Depending on other alloying elements like magnesium or zirconium, strongly required weight reduction, corrosion resistance and improved strength properties of metallic light weight alloys can be achieved. The development, production and testing of parts built up by a laser powder bed process will be presented with regard to the qualification of the new material concept "ScalmalloyRP®" for laser additive manufacturing.

  4. Synthesis and structural characterization of scandium SALEN complexes.

    Science.gov (United States)

    Meermann, Christian; Sirsch, Peter; Törnroos, Karl W; Anwander, Reiner

    2006-02-28

    A series of heteroleptic scandium SALEN complexes, [(SALEN)Sc(mu-Cl)]2 and (SALEN)Sc[N(SiHMe2)2] is obtained via amine elimination reactions using [Sc(N(i)Pr2)2(mu-Cl)(THF)]2 and Sc[N(SiHMe2)2]3(THF) as metal precursors, respectively. H(2)SALEN ligand precursors comprising H2Salen [(1,2-ethandiyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol], H2Salpren [(2,2-dimethylpropanediyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol], H2Salcyc [(1R,2R)-(-)-1,2-cyclohexanediyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol] and H2Salphen [((1S,2S)-(-)-1,2-diphenylethandiyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol] are selected according to solubility and ligand backbone variation ("=N-(R)-N=" bite angle) criteria. Consideration is given to the feasibility of [Cl --> NR2] and [N(SiHMe2)2--> OSiR3] secondary ligand exchange reactions. X-ray crystal structure analyses of donor-free (Salpren)Sc(N(i)Pr2), (R,R)-(Salcyc)Sc[N(SiHMe2)2], (Salen)Sc(OSi(t)BuPh2) and (Salphen)Sc(OSiH(t)Bu2) reveal (i) a very short Sc-N bond distance of 2.000(3) A, (ii) weak beta(Si-H)(amido)-Sc agostic interactions and (iii) an exclusive intramolecularly tetradentate and intrinsically bent coordination mode of the SALEN ligands with angle(Ph,Ph) dihedral angles and Sc-[N(2)O(2)] distances in the 124.27(9)-127.7(3) degrees and 0.638(1)-0.688(1) A range, respectively.

  5. Scandium SALEN complexes bearing chloro, aryloxo, and hydroxo ligands.

    Science.gov (United States)

    Meermann, Christian; Törnroos, Karl W; Anwander, Reiner

    2009-03-16

    Heteroleptic amide complexes (SALEN)Sc[N(SiHMe(2))(2)] (SALEN = Salen(tBu,tBu), Salcyc(tBu,tBu), or Salpren(tBu,tBu) if not stated differently) were examined as synthesis precursors according to silylamine elimination reactions. Treatment of (SALEN)Sc[N(SiHMe(2))(2)] with H(2)O or phenols (HOAr(R,R); R = tBu, iPr) afforded complexes [(SALEN)Sc(mu-OH)](2) and (SALEN)Sc(OAr(R,R)), while chloro exchange products were formed from the respective reactions with NH(4)Cl or AlMe(2)Cl. Such complexes [(SALEN)Sc(mu-Cl)](2) and (SALEN)ScCl(thf) were also obtained by utilizing alternative synthesis protocols, allowing for controlled donor absence and presence. Heteroleptic amide precursors [Sc(NiPr(2))(2)(mu-Cl)(thf)](2) and [Sc[N(SiHMe(2))(2)](2)(mu-Cl)(thf)](2) readily undergo amine elimination reactions with H(2)SALEN derivatives to form the corresponding chloride complexes. Spectroscopic and X-ray structural data of the heteroleptic scandium complexes revealed an exclusive intramolecular tetradentate coordination mode of the SALEN ligands independent of the SALEN ligand bite angle and the nature of the "second" ligand (chloro, amido, aryloxo, hydroxo). The coordination of the SALEN ligands is rationalized on the basis of (a) the displacement d of the metal center from the [N(2)O(2)] least-squares plane, (b) the dihedral angle alpha between the phenyl rings of the salicylidene moieties, and (c) the angle beta = Ct-Ln-Ct (Ct = centroid of the phenyl rings) in the case of strongly twisted ligands.

  6. Vertical distribution of scandium in the north central Pacific

    Science.gov (United States)

    Amakawa, Hiroshi; Nomura, Miho; Sasaki, Kazunori; Oura, Yasuji; Ebihara, Mitsuru

    2007-06-01

    The concentrations of scandium (Sc) in seawater, which have remained unreported since the early 1970s, were determined together with those of yttrium (Y) and lanthanides (Ln) with samples from the north central Pacific Ocean (St. BO-3). The Sc concentration shows a so-called nutrient-like profile: it increases gradually from the surface (about 2 pmol/kg) to the ocean floor (about 20 pmol/kg). That pattern closely resembles those of Y and Ln (correlation coefficient (r) > 0.92). Some light-to-middle Ln (Pr-Tb) exhibit a closer correlation with Sc than do Y, La, or heavy Ln (Ho-Lu). In contrast, Y/Sc and Ln/Sc ratios (elemental abundance ratios) indicate that Sc is depleted compared to either Y or Ln in seawater more than in loess, which represents chemical compositions of crustal material. These observations offer a conflicting view of chemical reactivity related Y, Ln, and Sc: r values show that the chemical reactivity of Sc resembles those of Y and Ln, but differences of Y/Sc and Ln/Sc ratios in seawater and in loess suggest that the chemical reactivity of Sc differs from those of Y and Ln. More Sc data for seawater are necessary to clarify the chemical reactivity of Sc in the ocean. We also propose that comparative studies of vertical profiles of Sc and such elements as Fe, Ti, Zr, and Hf showing so-called nutrient-like profiles at the same oceanic stations would be helpful and effective for clarifying the behavior of Sc in the ocean.

  7. In situ observation of the reaction of scandium and carbon by neutron diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Juarez-Arellano, Erick A., E-mail: eajuarez@unpa.edu.m [Institut fuer Geowissenschaften, Universitaet Frankfurt, Altenhoeferallee 1, 60438 Frankfurt a.M. (Germany); Universidad del Papaloapan, Circuito Central 200, Parque Industrial, Tuxtepec 68301 (Mexico); Winkler, Bjorn [Institut fuer Geowissenschaften, Universitaet Frankfurt, Altenhoeferallee 1, 60438 Frankfurt a.M. (Germany); Vogel, Sven C. [Los Alamos National Laboratory, Lujan Center. Mail Stop H805, Los Alamos, NM 87545 (United States); Senyshyn, Anatoliy [Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II), Technische Universitaet Muenchen, Lichtenbergstr. 1, D-85747 Garching (Germany); Materialwissenschaft, TU Darmstadt, Petersensstr. 23, D-64287 Darmstadt (Germany); Kammler, Daniel R. [Sandia National Laboratories, Albuquerque, NM 87185 (United States); Avalos-Borja, Miguel [CNyN, UNAM, A. Postal 2681, Ensenada, B.C. (Mexico)

    2011-01-05

    Research highlights: {yields} Exist two ScC cubic phases with B1-structure type differing in site occupancy of C. {yields} A new orthorhombic scandium carbide phase is formed at 1473(50) K. {yields} The recrystallization of alpha-Sc occurs between 1000 and 1223 K. - Abstract: The formation of scandium carbides by reaction of the elements has been investigated by in situ neutron diffraction up to 1823 K. On heating, the recrystallization of {alpha}-Sc occurs between 1000 and 1223 K. The formation of Sc{sub 2}C and ScC (NaCl-B1 type structure) phases has been detected at 1323 and 1373 K, respectively. The formation of a new orthorhombic scandium carbide phase was observed at 1473(50) K. Once the scandium carbides are formed they are stable upon heating or cooling. No other phases were detected in the present study, in which the system was always carbon saturated. The thermal expansion coefficients of all phases have been determined, they are constant throughout the temperature interval studied.

  8. The effects of aluminum or scandium on the toughness, density and ...

    African Journals Online (AJOL)

    The effects of the substitution of aluminum or scandium on the density, toughness as well as the stability of the phases formed by such an addition on platinum, iridium, rhodium and palladium metals were evaluated with the density functional quantum mechanical calculation methods. All the metals had four atoms per ...

  9. Effects of erbium‑and chromium‑doped yttrium scandium gallium ...

    African Journals Online (AJOL)

    2014-08-21

    Aug 21, 2014 ... surfaces because of its high power, and the ablation was deeper for these samples. High‑magnification SEM ... Key words: Erbium chromium‑doped yttrium scandium gallium garnet, diode laser, restorative dental materials, scanning electron ... garnet (Nd: YAG) and carbon dioxide (CO2) lasers on indirect ...

  10. Chemical and biological evaluation of scandium(III)-polyaminopolycarboxylate complexes as potential PET agents and radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Huclier-Markai, S.; Sabatie, A.; Ribet, S. [Univ. de Nantes (France). Lab. Subatech; Kubicek, V.; Hermann, P. [Charles Univ., Prague (Czech Republic). Dept. of Inorganic Chemistry; Paris, M. [Univ. de Nantes (France). Inst. des Materiaux; Vidaud, C. [CEA/DSV/iBEB/SBTN, Bagnols sur Ceze (France). Lab. d' Etude des Proteines Cibles; Cutler, C.S. [Univ. of Missouri, Columbia, MO (United States). Reserach Reactor Center

    2011-07-01

    Scandium isotopes ({sup 44}Sc, {sup 47}Sc) are more available and their properties are convenient for either PET imaging or radiotherapy. To use them in nuclear medicine, ligands forming complexes with a high stability are necessary. Available experimental data on stability constants for complexes of ligands such as EDTA, DTPA, DOTA, NOTA and TETA with various metal ions have been published. But scandium is the exception since scarce data is available in the literature. Values of stability constants of Sc(III) with the ligands were determined by free-ion selective radiotracer extraction, complemented by {sup 45}Sc NMR and potentiometry data. The thermodynamic stability of the Sc-complexes increases in the order TETA < NOTA < EDTA < DTPA < DOTA. The in vitro stability of the Sc(III) complexes was studied in the presence of hydroxyapatite and rat serum to estimate their in vivo stability. The most stable complex was shown to be Sc-DOTA.

  11. Precipitation behaviour and recrystallisation resistance in aluminum alloys with additions of hafnium, scandium and zirconium

    OpenAIRE

    Hallem, Håkon

    2005-01-01

    The overall objective of this work has been to develop aluminium alloys, which after hot and cold deformation are able to withstand high temperatures without recrystallising. This has been done by investigating aluminium alloys with various additions of hafnium, scandium and zirconium, with a main focus on Hf and to which extent it may partly substitute or replace Zr and/or Sc as a dispersoid forming elements in these alloys. What is the effect of hafnium, alone and in combination with Zr...

  12. Pilot-scale recovery of rare earths and scandium from phosphogypsum and uranium leachates

    Directory of Open Access Journals (Sweden)

    Mashkovtsev Maxim

    2016-01-01

    Full Text Available Ural Federal University (UrFU and VTT have performed joint research on development of industrial technologies for the extraction of REM and Scandium compounds from phosphogypsum and Uranium ISL leachate solutions. Leaching-absorption experiments at UrFU have been supported with multicomponent solution modelling by VTT. The simulations have been performed with VTT’s ChemSheet/Balas program and can be used for speciation calculations in the lixiviant solution. The experimental work combines solvent extraction with advanced ion exchange methodology in a pilot facility capable of treating 5 m3 solution per hour. Currently, the plant produces cerium carbonate, lanthanum oxide, neodymium oxide and concentrate of heavy rare earth metals. A batch of 45 t solids has been processed with the gain of 100 kg’s of REM concentrate. A mini-pilot plant with productivity above 50 liters per hour has been applied to recover scandium oxide and REE concentrates from the uranium ISL solution. As the preliminary product contains radioactivity (mainly strontium, an additional decontamination and cleaning of both concentrates by extraction has rendered a necessity. Finally a purified 99% concentrate of scandium oxide as well as 99% rare earth concentrate are received.

  13. Optimization of scandium oxide growth by high pressure sputtering on silicon

    Energy Technology Data Exchange (ETDEWEB)

    Feijoo, P.C., E-mail: pedronska@fis.ucm.es; Pampillon, M.A.; San Andres, E.; Lucia, M.L.

    2012-12-30

    This work demonstrates the viability of scandium oxide deposition on silicon by means of high pressure sputtering. Deposition pressure and radio frequency power are varied for optimization of the properties of the thin films and the ScO{sub x}/Si interface. The physical characterization was performed by ellipsometry, Fourier transform infrared spectroscopy, x-ray diffraction and transmission electron microscopy. Aluminum gate electrodes were evaporated for metal-insulator-semiconductor (MIS) fabrication. From the electrical characterization of the MIS devices, the density of interfacial defects is found to decrease with deposition pressure, showing a reduced plasma damage of the substrate surface for higher pressures. This is also supported by lower flatband voltage shifts in the capacitance versus voltage hysteresis curves. Sputtering at high pressures (above 100 Pa) reduces the interfacial SiO{sub x} formation, according to the infrared spectra. The growth rates decrease with deposition pressure, so a very accurate control of the layer thicknesses could be provided. - Highlights: Black-Right-Pointing-Pointer Scandium oxide is considered as a high permittivity dielectric. Black-Right-Pointing-Pointer Scandium oxide was deposited on Si by high pressure sputtering. Black-Right-Pointing-Pointer Characterization was performed for deposition condition optimization. Black-Right-Pointing-Pointer High deposition pressures showed higher film and interface quality.

  14. Recovery of Scandium from Leachate of Sulfation-Roasted Bayer Red Mud by Liquid-Liquid Extraction

    Science.gov (United States)

    Liu, Zhaobo; Li, Hongxu; Jing, Qiankun; Zhang, Mingming

    2017-11-01

    The leachate obtained from sulfation-roasted Bayer red mud is suitable for extraction of scandium by liquid-liquid solvent extraction because it contains trace amounts of Fe3+ and Si4+. In this study, a completely new metallurgical process for selective recovery of scandium from Bayer red mud was proposed. The extraction performances of Sc3+, Fe3+, Al3+, Si4+, Ca2+, and Na+ from synthetic leachate of sulfation-roasted red mud were first investigated using organophosphorus extractants (di-2-ethylhexyl phosphoric acid P204 and 2-ethylhexyl phosphoric acid mono-2-ethylhexyl ester P507) and carboxylic acid extractant (Versatic acid 10). It shows that P204 has an excellent extraction ability and that it can be applied to the scandium recovery. P507 and Versatic acid 10 are much poorer in performance for selective extraction of scandium. In the leachate of sulfation-roasted red mud, approximately 97% scandium can be recovered using a P204/sulfonated kerosene (1% v/v) extraction system under the condition of an organic-to-aqueous phase ratio of 10:1 and with an extraction temperature of 15°C.

  15. Scandium-doped zinc cadmium oxide as a new stable n-type oxide thermoelectric material

    DEFF Research Database (Denmark)

    Han, Li; Christensen, Dennis Valbjørn; Bhowmik, Arghya

    2016-01-01

    Scandium-doped zinc cadmium oxide (Sc-doped ZnCdO) is proposed as a new n-type oxide thermoelectric material. The material is sintered in air to maintain the oxygen stoichiometry and avoid instability issues. The successful alloying of CdO with ZnO at a molar ratio of 1 : 9 significantly reduced...... is a good candidate for improving the overall conversion efficiencies in oxide thermoelectric modules. Meanwhile, Sc-doped ZnCdO is robust in air at high temperatures, whereas other n-type materials, such as Al-doped ZnO, will experience rapid degradation of their electrical conductivity and ZT....

  16. Scandium and yttrium phosphasalen complexes as initiators for ring-opening polymerization of cyclic esters.

    Science.gov (United States)

    Bakewell, Clare; White, Andrew J P; Long, Nicholas J; Williams, Charlotte K

    2015-03-02

    The synthesis and characterization of novel scandium and yttrium phosphasalen complexes is reported, where phosphasalen refers to two different bis(iminophosphorane) derivatives of the more ubiquitous salen ligands. The activity of the complexes as initiators for the ring-opening polymerization of cyclic esters is presented. The scandium complexes are inactive for lactide polymerization but slow and controlled initiators for ε-caprolactone polymerization. The lack of activity toward lactide exhibited by these compounds is probed, and a rare example of single-monomer insertion product, unable to undergo further reactions with lactide, is identified. In contrast, the analogous yttrium phosphasalen complex is a very active initiator for the ring-opening polymerization of rac-lactide (kobs = 1.5 × 10(-3) s(-1) at 1:500 [yttrium initiator]:[rac-lactide], 1 M overall concentration of lactide in THF at 298 K). In addition to being a very fast initiator, the yttrium complex also maintains excellent levels of polymerization control and a high degree of isoselectivity, with the probability of isotactic enchainment being Pi = 0.78 at 298 K.

  17. Thermodynamic parameters of scandium trifluoride and triiodide in the condensed state

    Science.gov (United States)

    Aristova, N. M.; Belov, G. V.

    2015-06-01

    The thermodynamic properties of new classes of compounds, particularly scandium trihalides ScF3, ScCl3, ScBr3, and ScI3, are added to the IVTANTHERMO software package. A critical analysis and processing of the entire array of primary data available in the literature is performed. An equation approximating the temperature dependence of heat capacity in the temperature range 298.15- T m (K) is derived for each crystalline scandium trihalide. The resulting equations C {/p po}( T) for the solid state and the data for the liquid phase are used to calculate the thermodynamic functions of entropy, the reduced Gibbs free energies, and the enthalpy increments. Both the experimental data available in literature and the missing estimated thermodynamic data are used in calculations. The error of the recommended values is estimated in all cases. In the first part of this work, we describe the thermodynamic properties of ScF3 and ScI3 used as the reference data for calculating the thermodynamic functions of ScCl3 and ScBr3, for which experimental data are either very scarce or missing altogether. The resulting data are added to the database of the IVTANTHERMO software package.

  18. Recovery of Scandium(III) from Aqueous Solutions by Solvent Extraction with the Functionalized Ionic Liquid Betainium Bis(trifluoromethylsulfonyl)imide

    OpenAIRE

    Onghena, Bieke; Binnemans, Koen

    2015-01-01

    The ionic liquid betainium is(trifluoromethylsulfonyl)imide [Hbet][Tf2N] was used for the extraction of scandium from aqueous solutions. The influence of several extraction parameters on the extraction efficiency was investigated, including the initial metal concentration, phase ratio, and pH. The extraction kinetics was examined, and a comparison was made between conventional liquid−liquid extraction and homogeneous liquid−liquid extraction (HLLE). The stoichiometry of the extracted scandium...

  19. Modification mechanism of eutectic silicon in Al–6Si–0.3Mg alloy with scandium

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [Manufacturing and Systems Engineering Program, Department of Production Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand); Kajornchaiyakul, Julathep [National Metal and Material Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@kmutt.ac.th [Manufacturing and Systems Engineering Program, Department of Production Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2013-10-25

    Highlights: •Morphologies and growth of Sc and Sr-modified eutectic silicon resemble those of dendrites. •Crystal orientation of eutectic aluminum depends on growth characteristics of eutectic silicon. •We report strong evidence of the occurrence of an impurity-induced twinning mechanism. -- Abstract: The modification mechanism of eutectic silicon in Al–6Si–0.3Mg alloy with scandium was studied. The crystallographic orientation relationships between primary dendrites and the eutectic phase of unmodified and modified Al–6Si–0.3 Mg alloys were determined using electron backscatter diffraction (EBSD). The orientation of aluminum modified with scandium in the eutectic phase was different from that of the neighboring primary dendrites. This result implies that eutectic aluminum grows epitaxially from the surrounding primary aluminum dendrites in the unmodified alloy and that eutectic aluminum grows competitively from the surrounding primary aluminum dendrites in the modified alloy. The pole figure maps of eutectic Si in the [1 0 0], [1 1 0] and [1 1 1] axes of the unmodified and Sc-modified alloys were different, suggesting that the eutectic Al and Si crystals in modified alloy growth are more isotropic and cover a larger set of directions. The lattice fringes of Si of the alloys with and without Sc modification were different in the TEM results. The lattice fringes of Si in modified alloy were found to be multiple twins. However, this was not observed in the unmodified alloy. The growth characteristic of eutectic Si crystal in modified alloy suggests the occurrence of multiple twinning reactions and the formation of a high density of twins. This modification mechanism by Sc is explained by the results of scanning electron microscopy (SEM), electron backscatter diffraction (EBSD) and transmission electron microscopy (TEM) analysis, which provide strong evidence of the occurrence of the impurity-induced twinning (IIT) mechanism.

  20. Grain refinement mechanism in an Al-Si-Mg alloy with scandium

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [Department of Production Engineering, Faculty of Engineering, King Mongkut' s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand); Kajornchaiyakul, Julathep [National Metal and Material Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@kmutt.ac.th [Department of Production Engineering, Faculty of Engineering, King Mongkut' s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2012-11-25

    Highlights: Black-Right-Pointing-Pointer Scandium can be used to refine aluminum grains in an Al-Si-Mg aluminum alloy. Black-Right-Pointing-Pointer The effectiveness of Sc is lower than that of conventional Al-Ti grain refiners. Black-Right-Pointing-Pointer Al{sub 3}Sc particles can act as heterogeneous nuclei of aluminum phases. Black-Right-Pointing-Pointer Higher alloying elements cause more intermetallic compound phases. Black-Right-Pointing-Pointer Those phases cannot effectively act as heterogeneous nuclei compared with Al{sub 3}Sc particles. - Abstract: Grain refinement of the primary aluminum ({alpha}-Al) phase in a hypoeutectic Al-Si alloy using scandium (Sc) was studied to identify the grain refinement mechanism. Optical microscopy (OM), Scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS) and electron backscatter diffraction (EBSD) techniques were extensively used in this study. We found that Sc refined grains of primary aluminum. However, the grain refinement efficiency of Sc was considerably lower than that of titanium (Ti) in the Al-Si-Mg foundry alloy. It was evident that the precipitated Sc-containing phases acted as heterogeneous nucleation sites for the primary aluminum phase. The Sc-containing heterogeneous sites are irregular in shape with sizes between 3 and 5 {mu}m. At least three groups of nuclei based on their chemical composition were found, i.e., (i) Al and Sc, (ii) Al, Si, Mg, and Sc, and (iii) Al, Si, Mg, Sc, and Fe. Crystal orientation mapping showed primary aluminum dendrites with one orientation in each grain near Al{sub 3}Sc particles. The grain refinement mechanism of Sc for aluminum relies on heterogeneous nucleation of Al{sub 3}Sc particles, with less responsibly for grain growth restriction. Many intermetallic phases with Al, Si, Fe, Mg and Sc as their major components were found, and these phases could not effectively act as heterogeneous nuclei.

  1. Neutron and Charged-Particle Induced Cross Sections for Radiochemistry for Isotopes of Scandium, Titanium, Vanadium, Chromium, Manganese, and Iron

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, K; Hoffman, R D; Dietrich, F S; Bauer, R; Mustafa, M

    2004-11-30

    We have developed a set of modeled nuclear reaction cross sections for use in radiochemical diagnostics. Local systematics for the input parameters required by the Hauser-Feshbach statistical model were developed and used to calculate neutron and proton induced nuclear reaction cross sections in the mass region of scandium, titanium, vanadium, chromium, manganese, and iron (21 {le} Z {le} 26, 20 {le} N {le} 32).

  2. A composite cathode based on scandium doped titanate with enhanced electrocatalytic activity towards direct carbon dioxide electrolysis.

    Science.gov (United States)

    Yang, Liming; Xie, Kui; Wu, Lan; Qin, Qingqing; Zhang, Jun; Zhang, Yong; Xie, Ting; Wu, Yucheng

    2014-10-21

    A composite cathode based on redox-stable La0.2Sr0.8TiO(3+δ) (LSTO) can perform direct carbon dioxide electrolysis; however, the insufficient electro-catalytic activity limits the electrode performances and current efficiencies. In this work, catalytically active scandium is doped into LSTO to enhance the electro-catalytic activity for CO2 electrolysis. The structures, electronic conductivities and ionic conductivities of La0.2Sr0.8Ti(1-x)Sc(x)O (LSTS(x)O) (x = 0, 0.05, 0.1, 0.15 and 0.2) are systematically studied and further correlated with electrode performances. The ionic conductivities of single-phase LSTS(x)O (x = 0, 0.05, 0.1 and 0.15) remarkably improve versus the scandium doping contents though the electrical conductivities gradually change in an adverse trend. Electrochemical measurements demonstrate promising electrode polarisation of LSTS(x)O electrodes and increasing scandium doping contents accordingly improve electrode performances. The Faradic efficiencies of carbon dioxide electrolysis are enhanced by 20% with LSTS0.15O in contrast to bare LSTO electrodes in a solid oxide electrolyser at 800 °C.

  3. Adsorption of hydrogen in Scandium/Titanium decorated nitrogen doped carbon nanotube

    Energy Technology Data Exchange (ETDEWEB)

    Mananghaya, Michael, E-mail: mikemananghaya@gmail.com [De La Salle University, 2401 Taft Ave, 0922, Manila (Philippines); DLSU STC Laguna Boulevard, LTI Spine Road Barangays Biñan and Malamig, Biñan City, Laguna (Philippines); DOST-ASTHRDP, PCIEERD, Gen. Santos Ave., Bicutan, Taguig City 1631 (Philippines); Belo, Lawrence Phoa; Beltran, Arnel [De La Salle University, 2401 Taft Ave, 0922, Manila (Philippines); DLSU STC Laguna Boulevard, LTI Spine Road Barangays Biñan and Malamig, Biñan City, Laguna (Philippines)

    2016-09-01

    Nitrogen doped Carbon Nanotube with divacancy (4ND-CN{sub x}NT) that is decorated with Scandium and Titanium as potential hydrogen storage medium using the pseudo potential density functional method was investigated. Highly localized states near the Fermi level, which are derived from the nitrogen defects, contribute to strong Sc and Ti bindings, which prevent metal aggregation and improve the material stability. A detailed Comparison of the Hydrogen adsorption capability with promising system-weight efficiency of Sc over Ti was elucidated when functionalized with 4ND-CN{sub x}NT. Finally, the (Sc/4ND){sub 10}-CN{sub x}CNT composite material has a thermodynamically favorable adsorption and consecutive adsorption energy for ideal reversible adsorption and desorption of hydrogen at room temperature such that it can hold at least 5.8 wt% hydrogen molecules at the LDA and GGA level. - Highlights: • Carbon Nanotube with divacancy (4ND-CN{sub x}NT) decorated with Sc and Ti. • Nitrogen defects, contribute to strong Sc and Ti bindings. • H{sub 2} and (Sc/4ND){sub 10}-CN{sub x}CNT has a favorable adsorption. • 5.8 wt% adsorption at the LDA and GGA level.

  4. Urinary monitoring of exposure to yttrium, scandium, and europium in male Wistar rats.

    Science.gov (United States)

    Kitamura, Yasuhiro; Usuda, Kan; Shimizu, Hiroyasu; Fujimoto, Keiichi; Kono, Rei; Fujita, Aiko; Kono, Koichi

    2012-12-01

    On the assumption that rare earth elements (REEs) are nontoxic, they are being utilized as replacements of toxic heavy metals in novel technological applications. However, REEs are not entirely innocuous, and their impact on health is still uncertain. In the past decade, our laboratory has studied the urinary excretion of REEs in male Wistar rats given chlorides of europium, scandium, and yttrium solutions by one-shot intraperitoneal injection or oral dose. The present paper describes three experiments for the suitability and appropriateness of a method to use urine for biological monitoring of exposure to these REEs. The concentrations of REEs were determined in cumulative urine samples taken at 0-24 h by inductively coupled plasma atomic emission spectroscopy, showing that the urinary excretion of REEs is <2 %. Rare earth elements form colloidal conjugates in the bloodstream, which make high REEs accumulation in the reticuloendothelial system and glomeruli and low urinary excretion. The high sensitivity of inductively coupled plasma-argon emission spectrometry analytical methods, with detection limits of <2 μg/L, makes urine a comprehensive assessment tool that reflects REE exposure. The analytical method and animal experimental model described in this study will be of great importance and encourage further discussion for future studies.

  5. Selective recovery of vanadium and scandium by ion exchange with D201 and solvent extraction using P507 from hydrochloric acid leaching solution of red mud.

    Science.gov (United States)

    Zhu, Xiaobo; Li, Wang; Tang, Sen; Zeng, Majian; Bai, Pengyuan; Chen, Lunjian

    2017-05-01

    D201 resin and P507 extractant diluted with sulfonated kerosene were used to respectively separate vanadium and scandium, and impurity ions from hydrochloric acid leaching solution of red mud. More than 99% of vanadium was selectively adsorbed from the hydrochloric acid leaching solution under the conditions of pH value of 1.8, volume ratio of leaching solution to resin of 10, and flow rate of 3.33 mL/min. Maximum extraction and separation of scandium was observed from the acid leaching solution at an aqueous pH value of 0.2. More than 99% of scandium can be selectively extracted using 15% P507, 5% TBP at the aqueous solution/organic phase (A/O) ratio of 10:1 for 6 min. The loaded organic phase was washed with 0.3 mol/L sulfuric acid, wherein most impurities were removed. After the process of desorption or stripping, precipitation, and roasting, high-purity V2O5 and Sc2O3 were obtained. Finally, a conceptual flow sheet was established to separate and recover vanadium and scandium from red mud hydrochloric acid leaching solution. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Random-field Potts model for the polar domains of lead magnesium niobate and lead scandium tantalate

    Energy Technology Data Exchange (ETDEWEB)

    Qian, H.; Bursill, L.A

    1997-06-01

    A random filed Potts model is used to establish the spatial relationship between the nanoscale distribution of charges chemical defects and nanoscale polar domains for the perovskite-based relaxor materials lead magnesium niobate (PMN) and lead scandium tantalate (PST). The random fields are not set stochastically but are determined initially by the distribution of B-site cations (Mg, Nb) or (Sc, Ta) generated by Monte Carlo NNNI-model simulations for the chemical defects. An appropriate random field Potts model is derived and algorithms developed for a 2D lattice. It is shown that the local fields are strongly correlated with the chemical domain walls and that polar domains as a function of decreasing temperature is simulated for the two cases of PMN and PST. The dynamics of the polar clusters is also discussed. 33 refs., 9 figs.

  7. 38 CFR 61.61 - Agreement and funding actions.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.61 Agreement and funding actions. (a) When... designated for use, to assist homeless veterans. (j) VA may obligate any recovered funds without fiscal year... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Agreement and funding...

  8. Development of methods for the selective separation of scandium, zirconium and tin for radiopharmaceutical applications; Entwicklung von Methoden zur selektiven Trennung von Scandium, Zirkonium und Zinn fuer radiopharmazeutische Anwendungen

    Energy Technology Data Exchange (ETDEWEB)

    Dirks-Fandrei, Carina

    2014-07-01

    The subject of the present work is the development of fast and highly selective methods for the separation and purification of scandium, zirconium and tin radionuclides from potential target materials for use in nuclear medicine. A number of selected resins (TrisKem International) were first characterized with respect to their extraction behaviour towards a large number of cations. Characterization studies were performed in batch experiments by determination of weight distribution ratios D{sub w} and further the influence of interferences on the uptake of these elements was evaluated. Weight distribution ratios were determined in different acids and acid concentrations with main focus on scandium, tin or zirconium. The interference of macro amounts of Calcium and Ti on the Sc extraction was evaluated as well as the interference of macro amounts of Y on the Zr extraction. Best suited uptake conditions were found for Scandium on DGA were determined to be 2.5 M HNO{sub 3} for Ti-Targets and 0.1 M HNO{sub 3} for Calcium-Targets. Otherwise it is also possible to extract Sc with TRU Resin. High uptakes were obtained at 2.5 M HNO{sub 3} for simulated Ti- and Calcium-targets. Separation methods were developed using elution studies; employed conditions were chosen according to parameters evaluated in the batch-experiment. The developed methods allowed separating Sc very rapidly in high purity very rapidly from Ti- or Calcium-targets. For Zr a separation method based on UTEVA Resin has been developed. Following results of batch experiments simulated Y-target solution were loaded onto a UTEVA resin column from 6 M HNO{sub 3}; the elution of Zr could be performed in 0.01 M oxalic acid. Decontamination factors in the order of 10{sup 4}-10{sup 5} could be obtained applying the developed method; the method thus allowed separating Zr in a high purity. Initial testing of a method for the separation of Sn from Cd targets based on the use of TBP Resin showed that the TBP resin seems

  9. Results from NA61/SHINE

    Directory of Open Access Journals (Sweden)

    Unger M.

    2013-06-01

    Full Text Available In this paper we summarize recent results from NA61/SHINE relevant for heavy ion physics, neutrino oscillations and the interpretation of air showers induced by ultra-high energy cosmic rays.

  10. The impact of an erbium, chromium:yttrium-scandium-gallium-garnet laser with radial-firing tips on endodontic treatment.

    Science.gov (United States)

    Schoop, U; Barylyak, A; Goharkhay, K; Beer, F; Wernisch, J; Georgopoulos, A; Sperr, W; Moritz, A

    2009-01-01

    Radial-firing tips should allow a more homogeneous laser irradiation of root canal walls. The aim of the study was to assess the effects of erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser irradiation in conjunction with those newly designed tips. The investigation comprised bacteriology, morphological evaluations and temperature measurements. Root canals were inoculated with two test strains and laser irradiated with power settings of 0.6 W and 0.9 W and a repetition rate of 20 Hz. Subsequently, the samples were subjected to microbiological evaluation. The morphological changes of the canal walls were assessed by scanning electron microscopy. To reveal possible thermal side effects, we carried out temperature measurements. The bacteriological evaluation revealed a decisive disinfectant effect. Scanning electron microscopy showed the homogeneous removal of smear layer from the root canal walls. The temperature rise at the root surface during the irradiation was moderate, yielding 1.3 degrees C for the 0.6 W setting and 1.6 degrees C for the 0.9 W setting. The investigations indicated that the Er,Cr:YSGG laser, in conjunction with radial-firing tips, is a suitable tool for the elimination of bacteria in root canals and for the removal of smear layer.

  11. Effect of scandium addition on the microstructure, mechanical and wear properties of the spray formed hypereutectic aluminum–silicon alloys

    Energy Technology Data Exchange (ETDEWEB)

    Raghukiran, Nadimpalli; Kumar, Ravi, E-mail: nvrk@iitm.ac.in

    2015-08-12

    Hypereutectic Al–x%Si–0.8Sc alloys (x=13, 16, 19 and 22 wt%) were produced by spray forming. The microstructures of all the alloys exhibited very fine silicon phase with average size of about 5–10 µm irrespective of the silicon content of the alloy. Transmission electron microscopy revealed the presence of a nano-scale scandium rich phase, identified as AlSi{sub 2}Sc{sub 2} (V-phase) uniformly distributed in the alloy. The presence of V-phase resulted in higher matrix hardness (1.34 GPa) in contrast to 1.04 GPa observed in the case of binary Al–Si alloys by nanoindentation. Isothermal heat treatment at 375 °C revealed insignificant coarsening of silicon phase in both binary and ternary alloys. The Al–x%Si–0.8Sc alloys exhibited higher flow stress and tensile strength in contrast to their binary alloy counterparts which was attributed to the bi-modal size distribution of the strengthening phases in the form of nano-scale V-phase and sub-micron to 10 µm size silicon particles. The pin-on-disk wear tests exhibited appreciable improvement in the wear performance of the relatively low-silicon content ternary alloys over their binary counterparts while the high-silicon content binary and ternary alloys exhibited no much difference in the wear performance.

  12. Scandium and Titanium Containing Single-Walled Carbon Nanotubes for Hydrogen Storage: a Thermodynamic and First Principle Calculation.

    Science.gov (United States)

    Mananghaya, Michael; Yu, Dennis; Santos, Gil Nonato; Rodulfo, Emmanuel

    2016-06-15

    The generalized gradient approximation (GGA) to density functional theory (DFT) calculations indicate that the highly localized states derived from the defects of nitrogen doped carbon nanotube with divacancy (4ND-CNxNT) contribute to strong Sc and Ti bindings, which prevent metal aggregation. Comparison of the H2 adsorption capability of Sc over Ti-decorated 4ND-CNxNT shows that Ti cannot be used for reversible H2 storage due to its inherent high adsorption energy. The Sc/4ND-CNxNT possesses favorable adsorption and consecutive adsorption energy at the local-density approximation (LDA) and GGA level. Molecular dynamics (MD) study confirmed that the interaction between molecular hydrogen and 4ND-CNxNT decorated with scandium is indeed favorable. Simulations indicate that the total amount of adsorption is directly related to the operating temperature and pressure. The number of absorbed hydrogen molecules almost logarithmically increases as the pressure increases at a given temperature. The total excess adsorption of hydrogen on the (Sc/4ND)10-CNxNT arrays at 300 K is within the range set by the department of energy (DOE) with a value of at least 5.85 wt%.

  13. Private and Commercial Pilot: Glider. Flight Test Guide, Part 61 Revised, AC 61-61.

    Science.gov (United States)

    Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

    This flight test guide assists the applicant and his instructor in preparing for the Private or Commercial Pilot Certificate with Glider Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information and guidance concerning the pilot operations, procedures, and maneuvers relevant to the flight test required for that…

  14. Effects of scandium addition on iron-bearing phases and tensile properties of Al–7Si–0.6Mg alloys

    Energy Technology Data Exchange (ETDEWEB)

    Tzeng, Yu-Chih [Department of Mechanical Engineering, National Central University, Jhongli, Taiwan (China); Wu, Chih-Ting [Department of Vehicle Engineering, Army Academy R.O.C., Jhongli, Taiwan (China); Bor, Hui-Yun; Horng, Jain-Long; Tsai, Mu-Lin [Department of Mechanical Engineering, National Central University, Jhongli, Taiwan (China); Institute of Materials Science and Engineering, National Central University, Jhongli, Taiwan (China); Lee, Sheng-Long, E-mail: shenglon@cc.ncu.edu.tw [Department of Mechanical Engineering, National Central University, Jhongli, Taiwan (China); Institute of Materials Science and Engineering, National Central University, Jhongli, Taiwan (China)

    2014-01-21

    Iron is the most deleterious impurity in aluminum alloys and can easily combine with aluminum to form an acicular β-Al{sub 5}FeSi phase that reduces ductility during the solidification of the molten metal. Adding scandium (Sc) to Al–7Si–0.6Mg alloys can transform the acicular β-Al{sub 5}FeSi phase into a comparatively harmless nodular Sc–Fe phase (Al{sub 12}Si{sub 6}Fe{sub 2}(Mg,Sc){sub 5}). This Sc–Fe phase has a lower hardness and elastic modulus than the β-Al{sub 5}FeSi phase; it is thus less likely to initiate cracks in the Al matrix. Moreover, the nodular Sc–Fe phase can improve the fluidity of Al during solidification, reducing interdendritic shrinkage. Tensile testing measurements showed that the elongation of Al–7Si–0.6Mg alloys with 0.04 and 0.12 wt% Sc can be respectively increased by 115% and 110% compared to Al–7Si–0.6Mg without Sc. The corresponding quality indices are increased by 17% and 19%, respectively, suggesting that the tensile properties of Al–7Si–0.6Mg alloys can be enhanced by adding scandium.

  15. Separation of (44)Ti from proton irradiated scandium by using solid-phase extraction chromatography and design of (44)Ti/(44)Sc generator system.

    Science.gov (United States)

    Radchenko, V; Meyer, C A L; Engle, J W; Naranjo, C M; Unc, G A; Mastren, T; Brugh, M; Birnbaum, E R; John, K D; Nortier, F M; Fassbender, M E

    2016-12-16

    Scandium-44g (half-life 3.97h [1]) shows promise for positron emission tomography (PET) imaging of longer biological processes than that of the current gold standard, (18)F, due to its favorable decay parameters. One source of (44g)Sc is the long-lived parent nuclide (44)Ti (half-life 60.0 a). A (44)Ti/(44g)Sc generator would have the ability to provide radionuclidically pure (44g)Sc on a daily basis. The production of (44)Ti via the (45)Sc(p,2n) reaction requires high proton beam currents and long irradiation times. Recovery and purification of no-carrier added (nca) (44)Ti from scandium metal targets involves complex separation chemistry. In this study, separation systems based on solid phase extraction chromatography were investigated, including branched diglycolamide (BDGA) resin and hydroxamate based ZR resin. Results indicate that ZR resin in HCl media represents an effective (44)Ti/(44g)Sc separation system. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. 40 CFR 61.44 - Stack sampling.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Stack sampling. 61.44 Section 61.44 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... Firing § 61.44 Stack sampling. (a) Sources subject to § 61.42(b) shall be continuously sampled, during...

  17. Subacute thyroiditis--61 cases review.

    Science.gov (United States)

    Hwang, S C; Jap, T S; Ho, L T; Ching, K N

    1989-02-01

    To examine the hospitalized patients with available data suggesting subacute thyroiditis, we have reviewed 80 hospital charts over the last 11 years and the data demonstrated 61 patients (48 females, 13 males, Aged 22-75 years) had evidence of subacute thyroiditis clinically or pathologically. Fifty seven of those patients had the clinical manifestation of severe tenderness over the neck, and others were painless. The thyroid function test were abnormal in 53% (30/57) of cases. All had rapid sedimentation rate (46/46). The thyroid antibodies were positive in 26% (10/39) of cases. Sixteen patients received unnecessary thyroid operation and complicated with hypothyroidism with or without hypoparathyroidism in two cases. In conclusion, all patients with painful or painless goiter should be appreciated carefully with additional study such as aspiration cytology to avoid misdiagnosis and inappropriate management.

  18. Gd-Sc-based mixed-metal nitride cluster fullerenes: mutual influence of the cage and cluster size and the role of scandium in the electronic structure.

    Science.gov (United States)

    Svitova, Anna L; Popov, Alexey A; Dunsch, Lothar

    2013-03-18

    The influence of the cage as well as of the cluster size has been studied in Gd-Sc nitride cluster fullerenes, which have been synthesized and isolated for these studies. A series of carbon cages ranging from C78 to C88 have been synthesized, isolated, and characterized in detail using absorption and vibrational spectroscopy as well as electrochemistry and density functional theory calculations. Gd-Sc mixed-metal cluster fullerenes in carbon cages different from C80 were described for the first time. A review of their structures, properties, and stability is given. The synthesis was performed with melamine as an effective solid source of nitrogen, providing high fullerene yield and suppressing empty fullerene formation. Substitution of gadolinium by scandium imposes a noticeable influence on the electronic structure of nitride cluster fullerenes as revealed by electrochemical, spectroscopic, and computational methods.

  19. 47 CFR 61.171 - Adoption notice.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Adoption notice. 61.171 Section 61.171 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) TARIFFS Adoption of Tariffs and Other Documents of Predecessor Carriers § 61.171 Adoption notice. When a carrier's...

  20. 21 CFR 640.61 - Informed consent.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 7 2010-04-01 2010-04-01 false Informed consent. 640.61 Section 640.61 Food and... ADDITIONAL STANDARDS FOR HUMAN BLOOD AND BLOOD PRODUCTS Source Plasma § 640.61 Informed consent. The written... and informed consent be given and that a clear opportunity to refuse is presented. ...

  1. 7 CFR 1735.61 - Approval criteria.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Approval criteria. 1735.61 Section 1735.61 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF... on Acquisitions and Mergers § 1735.61 Approval criteria. (a) If a borrower is required by the terms...

  2. 38 CFR 61.63 - Procedural error.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Procedural error. 61.63 Section 61.63 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.63 Procedural error. If an application would have been...

  3. 38 CFR 61.65 - Inspections.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Inspections. 61.65 Section 61.65 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.65 Inspections. VA may inspect the facility and any...

  4. 38 CFR 61.62 - Program changes.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Program changes. 61.62 Section 61.62 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.62 Program changes. (a) Except as provided in paragraphs...

  5. 38 CFR 61.81 - Outreach activities.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Outreach activities. 61.81 Section 61.81 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.81 Outreach activities. Recipients of capital...

  6. 40 CFR 61.05 - Prohibited activities.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Prohibited activities. 61.05 Section 61.05 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.05 Prohibited activities...

  7. 22 CFR 61.9 - General information.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false General information. 61.9 Section 61.9 Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.9 General information. General information and application forms may be obtained by writing to the...

  8. 32 CFR 154.61 - Security education.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Security education. 154.61 Section 154.61... PERSONNEL SECURITY PROGRAM REGULATION Continuing Security Responsibilities § 154.61 Security education. (a.... Through security briefings and education, the Department of Defense continues to provide for the...

  9. 40 CFR 61.34 - Air sampling.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Air sampling. 61.34 Section 61.34... sampling. (a) Stationary sources subject to § 61.32(b) shall locate air sampling sites in accordance with a... concentrations calculated within 30 days after filters are collected. Records of concentrations at all sampling...

  10. 40 CFR 61.33 - Stack sampling.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Stack sampling. 61.33 Section 61.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) NATIONAL... sampling. (a) Unless a waiver of emission testing is obtained under § 61.13, each owner or operator...

  11. 31 CFR 8.61 - Representation.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Representation. 8.61 Section 8.61 Money and Finance: Treasury Office of the Secretary of the Treasury PRACTICE BEFORE THE BUREAU OF ALCOHOL, TOBACCO AND FIREARMS Disciplinary Proceedings § 8.61 Representation. A respondent or proposed...

  12. 45 CFR 61.16 - Immunity.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Immunity. 61.16 Section 61.16 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK... Information by the Healthcare Integrity and Protection Data Bank § 61.16 Immunity. Individuals, entities or...

  13. 10 CFR 61.9 - Employee protection.

    Science.gov (United States)

    2010-01-01

    ... occurs because the employee has engaged in protected activities. An employee's engagement in protected... 10 Energy 2 2010-01-01 2010-01-01 false Employee protection. 61.9 Section 61.9 Energy NUCLEAR... Provisions § 61.9 Employee protection. (a) Discrimination by a Commission licensee, an applicant for a...

  14. 49 CFR 570.61 - Suspension system.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Suspension system. 570.61 Section 570.61 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY... 10,000 Pounds § 570.61 Suspension system. (a) Suspension condition. Ball joint seals shall not be cut...

  15. 49 CFR 229.61 - Draft system.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Draft system. 229.61 Section 229.61 Transportation... TRANSPORTATION RAILROAD LOCOMOTIVE SAFETY STANDARDS Safety Requirements Draft System § 229.61 Draft system. (a) A.... Suspension System ...

  16. 28 CFR 61.1 - Background.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Background. 61.1 Section 61.1 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT General § 61.1 Background. (a) The National Environmental Policy Act of 1969 (NEPA), 42 U.S.C...

  17. 45 CFR 61.3 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Definitions. 61.3 Section 61.3 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK... § 61.3 Definitions. The following definitions apply to this part: Act means the Social Security Act...

  18. 24 CFR 200.61 - Title.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Title. 200.61 Section 200.61... Requirements for Existing Projects General Requirements § 200.61 Title. (a) Marketable title to the project must be vested in the mortgagor as of the date the mortgage is filed for record. (b) Title evidence for...

  19. 47 CFR 61.16 - Base documents.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Base documents. 61.16 Section 61.16... for Electronic Filing § 61.16 Base documents. (a) The Base Document is a complete tariff which incorporates all effective revisions, as of the last day of the preceding month. The Base Document should be...

  20. 42 CFR 498.61 - Evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Evidence. 498.61 Section 498.61 Public Health... PROGRAM Hearings § 498.61 Evidence. Evidence may be received at the hearing even though inadmissible under the rules of evidence applicable to court procedure. The ALJ rules on the admissibility of evidence. ...

  1. 40 CFR 792.61 - Equipment design.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Equipment design. 792.61 Section 792.61...) GOOD LABORATORY PRACTICE STANDARDS Equipment § 792.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall be...

  2. 21 CFR 58.61 - Equipment design.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Equipment design. 58.61 Section 58.61 Food and... PRACTICE FOR NONCLINICAL LABORATORY STUDIES Equipment § 58.61 Equipment design. Equipment used in the... of appropriate design and adequate capacity to function according to the protocol and shall be...

  3. 40 CFR 61.345 - Standards: Containers.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standards: Containers. 61.345 Section... Operations § 61.345 Standards: Containers. (a) The owner or operator shall meet the following standards for each container in which waste is placed in accordance with § 61.342(c)(1)(ii) of this subpart: (1) The...

  4. 7 CFR 915.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 915.61 Section 915.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Miscellaneous Provisions § 915.61 Compliance. Except as provided in this part, no person...

  5. 7 CFR 925.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 925.61 Section 925.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... SOUTHEASTERN CALIFORNIA Miscellaneous Provisions § 925.61 Compliance. Except as provided in this part, no...

  6. 7 CFR 923.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 923.61 Section 923.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... COUNTIES IN WASHINGTON Order Regulating Handling Miscellaneous Provisions § 923.61 Compliance. Except as...

  7. 7 CFR 924.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 924.61 Section 924.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... § 924.61 Compliance. Except as provided in this part, no person shall handle prunes, the shipment of...

  8. 7 CFR 916.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 916.61 Section 916.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Regulating Handling Miscellaneous Provisions § 916.61 Compliance. Except as provided in this part, no person...

  9. 7 CFR 922.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 922.61 Section 922.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... IN WASHINGTON Order Regulating Handling Miscellaneous Provisions § 922.61 Compliance. Except as...

  10. 7 CFR 920.61 - Compliance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Compliance. 920.61 Section 920.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... Miscellaneous Provisions § 920.61 Compliance. (a) Except as provided in this part, no person shall handle...

  11. 14 CFR 31.61 - Static discharge.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Static discharge. 31.61 Section 31.61 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS STANDARDS: MANNED FREE BALLOONS Design Construction § 31.61 Static discharge. Unless shown not to be...

  12. 48 CFR 9904.403-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.403-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.403-61 Interpretation. (a) Questions have arisen as to...

  13. 48 CFR 9904.401-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.401-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.401-61 Interpretation. (a) 9904.401, Cost Accounting...

  14. 48 CFR 9904.402-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.402-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.402-61 Interpretation. (a) 9904.402, Cost Accounting...

  15. 21 CFR 808.61 - Hawaii.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Hawaii. 808.61 Section 808.61 Food and Drugs FOOD... and Local Exemptions § 808.61 Hawaii. (a) The following Hawaii medical device requirements are... from preemption under section 521(b) of the act: Hawaii Revised Statutes, chapter 451A, § 14.1...

  16. 38 CFR 61.0 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Purpose. 61.0 Section 61.0 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.0 Purpose. This part implements the VA Homeless Providers Grant...

  17. 49 CFR 511.61 - Purpose.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 6 2010-10-01 2010-10-01 false Purpose. 511.61 Section 511.61 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION... Fuel Economy Standards § 511.61 Purpose. This subpart establishes the procedures and requirements...

  18. 7 CFR 3550.61 - Insurance.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Insurance. 3550.61 Section 3550.61 Agriculture... DIRECT SINGLE FAMILY HOUSING LOANS AND GRANTS Section 502 Origination § 3550.61 Insurance. (a) Borrower... furnish and continually maintain hazard insurance on the security property, with companies, in amounts...

  19. 7 CFR 30.61 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Administration. 30.61 Section 30.61 Agriculture... AND STANDARDS Administration § 30.61 Administration. The Director, Tobacco Division, Agricultural... the Division and the performance of all duties assigned thereto in the administration of the Tobacco...

  20. 10 CFR 61.56 - Waste characteristics.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Waste characteristics. 61.56 Section 61.56 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Technical Requirements for Land Disposal Facilities § 61.56 Waste characteristics. (a) The following requirements are...

  1. 40 CFR 61.21 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Definitions. 61.21 Section 61.21... Underground Uranium Mines § 61.21 Definitions. As used in this subpart, all terms not defined here have the... in biological effectiveness due to the quality of radiation and its distribution in the body of...

  2. 40 CFR 61.91 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Definitions. 61.91 Section 61.91... Other Than Radon From Department of Energy Facilities § 61.91 Definitions. As used in this subpart, all... biological effectiveness due to the quality of radiation and its distribution in the body of reference man...

  3. 42 CFR 61.12 - Accountability.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Accountability. 61.12 Section 61.12 Public Health... FELLOWSHIPS Regular Fellowships § 61.12 Accountability. Payments shall be subject to such requirements relating to accountability as may be specified by the Surgeon General. ...

  4. 16 CFR 1615.61 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false 1615.61 Section 1615.61 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION FLAMMABLE FABRICS ACT REGULATIONS STANDARD FOR THE FLAMMABILITY OF CHILDREN'S SLEEPWEAR: SIZES 0 THROUGH 6X (FF 3-71) Interpretations and Policies § 1615.61 ...

  5. 10 CFR 61.13 - Technical analyses.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Technical analyses. 61.13 Section 61.13 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Licenses § 61.13 Technical analyses. The specific technical information must also include the following analyses...

  6. 7 CFR 3016.61 - Financial reporting.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Financial reporting. 3016.61 Section 3016.61... AND LOCAL GOVERNMENTS Entitlement § 3016.61 Financial reporting. The financial reporting provisions... Food Distribution Program on Indian Reservations. The financial reporting requirements for these...

  7. 14 CFR 61.98 - Flight proficiency.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight proficiency. 61.98 Section 61.98... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Recreational Pilots § 61.98 Flight proficiency... and flight training from an authorized instructor on the areas of operation of this section that apply...

  8. 14 CFR 61.56 - Flight review.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight review. 61.56 Section 61.56... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.56 Flight review. (a) Except as provided in paragraphs (b) and (f) of this section, a flight review consists of a minimum of 1 hour of...

  9. 14 CFR 61.187 - Flight proficiency.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight proficiency. 61.187 Section 61.187... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors Other than Flight Instructors With a Sport Pilot Rating § 61.187 Flight proficiency. (a) General. A person who is applying for a...

  10. 14 CFR 61.157 - Flight proficiency.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight proficiency. 61.157 Section 61.157... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Airline Transport Pilots § 61.157 Flight... and log ground and flight training from an authorized instructor on the areas of operation under this...

  11. 14 CFR 61.107 - Flight proficiency.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight proficiency. 61.107 Section 61.107... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Private Pilots § 61.107 Flight proficiency. (a) General. A person who applies for a private pilot certificate must receive and log ground and flight...

  12. Copper scandium zirconium phosphate

    DEFF Research Database (Denmark)

    Bond, Andrew David; Warner, Terence Edwin

    2013-01-01

    components. The [Sc(III)Zr(IV)(PO(4))(3)](2-) framework is composed of corner-sharing Sc/ZrO(6) octahedra and PO(4) tetrahedra. The Sc and Zr atoms are disordered on one atomic site on a crystallographic threefold axis. The P atom of the phosphate group lies on a crystallographic twofold axis. Nonframework...

  13. 44 CFR Appendix A(5) to Part 61 - Appendix A(5) to Part 61

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Appendix A(5) to Part 61 A(5) Appendix A(5) to Part 61 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... COVERAGE AND RATES Pt. 61, App. A(5) Appendix A(5) to Part 61 Federal Emergency Management Agency, Federal...

  14. 44 CFR Appendix A(6) to Part 61 - Appendix A(6) to Part 61

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Appendix A(6) to Part 61 A(6) Appendix A(6) to Part 61 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... COVERAGE AND RATES Pt. 61, App. A(6) Appendix A(6) to Part 61 Federal Emergency Management Agency, Federal...

  15. 44 CFR Appendix A(4) to Part 61 - Appendix A(4) to Part 61

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Appendix A(4) to Part 61 A(4) Appendix A(4) to Part 61 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... COVERAGE AND RATES Pt. 61, App. A(4) Appendix A(4) to Part 61 Federal Emergency Management Agency, Federal...

  16. Synthesis and characterization of reduced scandium halide containing one- and two-dimensional metal bonded arrays. [Sc--ScCl3; Cs3Sc2Cl9; CsScCl3

    Energy Technology Data Exchange (ETDEWEB)

    Poeppelmeier, K.R.

    1978-08-01

    The stabilization effect of metal-metal bond formation on reduced scandium compounds was studied. The binary compounds Sc/sub 7/Cl/sub 12/, Sc/sub 5/Cl/sub 8/, Sc/sub 7/Cl/sub 10/ and ScCl were prepared by high temperature techniques and were characterized by single crystal x-ray diffraction. The respective metal arrays in these compounds can be viewed as fragments of scandium metal ranging from discrete six atom metal cluster species (Sc(Sc/sub 6/Cl/sub 12/)), through intermediate single and double infinite chain configurations ((ScCl/sub 2/)(Sc/sub 4/Cl/sub 6/)) and ((ScCl/sub 2/)(Sc/sub 6/Cl/sub 8/)) to double metal close-packed sheets (ScCl). The halogen atoms effectively isolate the clusters, chains and sheets by bonding face, edge or exo positions on the metal arrays. The common occurrence of isolated scandium (III) ions emphasizes that a minimum number of bonding electrons is required to stabilize what are formally anionic metal arrays. The distribution of the reduction electrons in these anisotropic materials was studied by magnetic susceptibility, EPR and uv-X photoelectron spectroscopy. The ternary compounds studied were Cs/sub 3/Sc/sub 2/Cl/sub 9/ and CsScCl/sub 3/. The anion-bridged metal chain of the hexagonal perovskite structure was found to stabilize scandium (II). CsScCl/sub 3/ was found to be grossly nonstoichiometric on the transition metal site and the effects of the mixed valence character were studied between the single valence extremes Cs/sub 3/Sc/sub 2 + x/Cl/sub 9/; 0< x < 1.0.

  17. Scandium functionalized carbon aerogel: Synthesis of nanoparticles and structure of a new ScOCl and properties of NaAlH{sub 4} as a function of pore size

    Energy Technology Data Exchange (ETDEWEB)

    Javadian, Payam; Nielsen, Thomas K. [Center for Energy Materials, Interdisciplinary Nanoscience Center (iNANO), and Department of Chemistry, Aarhus University, DK-8000 Aarhus (Denmark); Ravnsbæk, Dorthe B. [Department of Material Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge 02142, MA (United States); Jepsen, Lars H. [Center for Energy Materials, Interdisciplinary Nanoscience Center (iNANO), and Department of Chemistry, Aarhus University, DK-8000 Aarhus (Denmark); Polanski, Marek [Faculty of Advanced Technology and Chemistry, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw (Poland); Plocinski, Tomasz [Faculty of Material Science and Engineering, Warsaw University of Technology, 144 Woloska Str., 02-507 Warsaw (Poland); Kunce, Izabela [Faculty of Advanced Technology and Chemistry, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw (Poland); Besenbacher, Flemming [Interdisciplinary Nanoscience Center (iNANO) and Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Bystrzycki, Jerzy [Faculty of Advanced Technology and Chemistry, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw (Poland); Jensen, Torben R., E-mail: trj@chem.au.dk [Center for Energy Materials, Interdisciplinary Nanoscience Center (iNANO), and Department of Chemistry, Aarhus University, DK-8000 Aarhus (Denmark)

    2015-11-15

    A new method for scandium-functionalization of carbon aerogels forming nanoparticles of a new scandiumoxochloride, ScOCl is presented. Sodium aluminiumhydride, NaAlH{sub 4}, is successfully melt infiltrated into the nano porous scaffolds with pore sizes of D{sub max}=7, 10, 13, 21, 26 and 39 nm, containing scandium based nano particles (<2.9 wt%) confirmed by elemental analysis and scanning electron microscopy. A systematic study of hydrogen storage properties of the nano composite materials is presented. An aqueous solution of ScCl{sub 3} was initially infiltrated and formed nanoconfined [Sc(OH)(H{sub 2}O){sub 5}]{sub 2}Cl{sub 4}(H{sub 2}O){sub 2}, which transforms to nanoparticles of a new scandium oxochloride, ScOCl at 192 °C and to Sc{sub 2}O{sub 3} at 420 °C. ScOCl crystallizes in an orthorhombic unit cell a=3.4409(8), b=3.9613(6) and c=8.178(2) Å, space group Pmmn, and is built from layers of [ScO{sub 4}Cl{sub 2}] octahedra forming neutral ScOCl layers. Temperature programmed desorption mass spectroscopy shows slightly improved kinetics for release of hydrogen with decreasing pore size. Continuous cycling of hydrogen release and uptake measured by the Sieverts' method reveal a larger preserved hydrogen storage capacity for scandium-functionalized aerogel with the larger pores (39 nm). - Highlights: • New synthesis approach for nanoporous Sc-functionalization carbon aerogel (Sc-CA). • The new scandium oxochloride, ScOCl, structure is obtained. • NaAlH{sub 4} nanoconfined in Sc-CA with pores ranging between 7 nm

  18. 24 CFR 242.61 - Management.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Management. 242.61 Section 242.61... Management. The mortgagor shall provide for management of the hospital in a manner satisfactory to HUD. (a) Contract Management of Hospital. The mortgagor shall not execute a management agreement or any other...

  19. 38 CFR 61.66 - Financial management.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Financial management. 61...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.66 Financial management. (a) All recipients... management system that follows generally accepted accounting principals and provides accounting records...

  20. 15 CFR 930.61 - Public participation.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Public participation. 930.61 Section... a Federal License or Permit § 930.61 Public participation. (a) Following receipt of the material... activity, as determined by the State agency. At the discretion of the State agency, public participation...

  1. 7 CFR 58.61 - Political activity.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Political activity. 58.61 Section 58.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE...

  2. 38 CFR 61.67 - Recovery provisions.

    Science.gov (United States)

    2010-07-01

    ...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.67 Recovery provisions. (a) If after 3 years... status within 3 years from the time of award. Grantee B then provides services to homeless veterans for a... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Recovery provisions. 61...

  3. 19 CFR 181.61 - Applicability.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Applicability. 181.61 Section 181.61 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY... purposes of the re-entry of goods after repair or alteration in Canada or Mexico as provided for in Article...

  4. 22 CFR 217.61 - Procedures.

    Science.gov (United States)

    2010-04-01

    ... applicable to title VI of the Civil Rights Act of 1964 apply to this part. These procedures are found in... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Procedures. 217.61 Section 217.61 Foreign Relations AGENCY FOR INTERNATIONAL DEVELOPMENT NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR...

  5. 14 CFR 61.105 - Aeronautical knowledge.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aeronautical knowledge. 61.105 Section 61... Aeronautical knowledge. (a) General. A person who is applying for a private pilot certificate must receive and... knowledge areas of paragraph (b) of this section that apply to the aircraft category and class rating sought...

  6. 14 CFR 61.155 - Aeronautical knowledge.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aeronautical knowledge. 61.155 Section 61....155 Aeronautical knowledge. (a) General. The knowledge test for an airline transport pilot certificate is based on the aeronautical knowledge areas listed in paragraph (c) of this section that are...

  7. 14 CFR 61.97 - Aeronautical knowledge.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aeronautical knowledge. 61.97 Section 61.97... knowledge. (a) General. A person who applies for a recreational pilot certificate must receive and log... knowledge areas of paragraph (b) of this section that apply to the aircraft category and class rating sought...

  8. 45 CFR 74.61 - Termination.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Termination. 74.61 Section 74.61 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION UNIFORM ADMINISTRATIVE REQUIREMENTS FOR AWARDS AND SUBAWARDS TO INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, OTHER NONPROFIT ORGANIZATIONS, AND COMMERCIAL ORGANIZATIONS Post-Award...

  9. 40 CFR 160.61 - Equipment design.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Equipment design. 160.61 Section 160... LABORATORY PRACTICE STANDARDS Equipment § 160.61 Equipment design. Equipment used in the generation... appropriate design and adequate capacity to function according to the protocol and shall be suitably located...

  10. 40 CFR 123.61 - Approval process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Approval process. 123.61 Section 123... REQUIREMENTS Program Approval, Revision, and Withdrawal § 123.61 Approval process. (a) After determining that a...; and (6) Briefly outline the fundamental aspects of the State's proposed program, and the process for...

  11. 24 CFR 84.61 - Termination.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Termination. 84.61 Section 84.61 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER...

  12. 40 CFR 428.61 - Specialized definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Specialized definitions. 428.61 Section 428.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS RUBBER MANUFACTURING POINT SOURCE CATEGORY Medium-Sized General Molded, Extruded, and...

  13. 40 CFR 61.23 - Determining compliance.

    Science.gov (United States)

    2010-07-01

    .... Environmental Protection Agency (EPA) computer code COMPLY-R. An underground uranium mine owner or operator... 61.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED... From Underground Uranium Mines § 61.23 Determining compliance. (a) Compliance with the emission...

  14. 37 CFR 3.61 - Domestic representative.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Domestic representative. 3.61... COMMERCE GENERAL ASSIGNMENT, RECORDING AND RIGHTS OF ASSIGNEE Domestic Representative § 3.61 Domestic... is not domiciled in the United States, the assignee may designate a domestic representative in a...

  15. 39 CFR 447.61 - General.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false General. 447.61 Section 447.61 Postal Service UNITED STATES POSTAL SERVICE PERSONNEL RULES OF CONDUCT FOR POSTAL EMPLOYEES Bribery, Undue Influence, or... Service uses or attempts to use a bribe, undue influence, or coercion to induce or attempt to induce the...

  16. 19 CFR 115.61 - Eligibility.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Eligibility. 115.61 Section 115.61 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS CONVENTIONS Procedures...

  17. 40 CFR 61.101 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Definitions. 61.101 Section 61.101....101 Definitions. As used in this subpart, all terms not defined here have the meaning given them in... factors to account for differences in biological effectiveness due to the quality of radiation and its...

  18. 48 CFR 9904.406-61 - Interpretation.

    Science.gov (United States)

    2010-10-01

    ... capital cost of money. (j) Restructuring costs incurred at a home office level shall be treated in... more than one segment should be allocated to the home office and treated as home office expense...-61 Section 9904.406-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE...

  19. 7 CFR 948.61 - Procedure.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Procedure. 948.61 Section 948.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements... members, to vote by mail, telegraph, telephone, or other means of communication, provided that any such...

  20. 29 CFR 1956.61 - Developmental Schedule.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Developmental Schedule. 1956.61 Section 1956.61 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) STATE PLANS FOR THE DEVELOPMENT AND ENFORCEMENT OF STATE STANDARDS APPLICABLE TO STATE AND LOCAL...

  1. The use of the erbium, chromium:yttrium-scandium-gallium-garnet laser in endodontic treatment: the results of an in vitro study.

    Science.gov (United States)

    Schoop, Ulrich; Goharkhay, Kawe; Klimscha, Johannes; Zagler, Manuela; Wernisch, Johann; Georgopoulos, Apostolos; Sperr, Wolfgang; Moritz, Andreas

    2007-07-01

    The use of the erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser has become accepted in the field of cavity preparation. The development of miniaturized and flexible fiber tips has allowed this device to be used in endodontics. The authors conducted an in vitro study to assess the effects of Er,Cr:YSGG laser irradiation on root canals. The authors inoculated root canals with two bacteria, laser irradiated them at two power settings and subjected them to a quantitative microbiological evaluation. They used scanning electron microscopy (SEM) to assess morphological changes in endodontically processed and laser-irradiated root canal walls. They measured temperature increases on the root surface to determine possible thermal side effects. The bacteriological evaluation revealed a disinfecting effect in the root dentin samples that was dependent on the output power but not specific for the bacterial species investigated. SEM showed the removal of the smear layer from the root canal walls and the exposure of dentinal tubules. The temperature rise during irradiation was moderate when standardized power settings were used. The Er,Cr:YSGG laser can be used to eliminate bacteria in root canals. It also effectively removes smear layer and debris from the canal wall. Practitioners can use the Er,Cr:YSGG laser to prepare root canals for endodontic therapy.

  2. Aluminum-Scandium Alloys: Material Characterization, Friction Stir Welding, and Compatibility With Hydrogen Peroxide (MSFC Center Director's Discretionary Fund Final Report, Proj. No. 04-14)

    Science.gov (United States)

    Lee, J. A.; Chen, P. S.

    2004-01-01

    This Technical Memorandum describes the development of several high-strength aluminum (Al) alloys that are compatible with hydrogen peroxide (H2O2) propellant for NASA Hypersonic-X (Hyper-X) vehicles fuel tanks and structures. The yield strengths for some of these Al-magnesium-based alloys are more than 3 times stronger than the conventional 5254-H112 Al alloy, while maintaining excellent H2O2 compatibility similar to class 1 5254 alloy. The alloy development strategy is to add scandium, zirconium, and other transitional metals with unique electrochemical properties, which will not act as catalysts, to decompose the highly concentrated 90 percent H2O2. Test coupons are machined from sheet metals for H2O2 long-term exposure testing and mechanical properties testing. In addition, the ability to weld the new alloys using friction stir welding has also been explored. The new high-strength alloys could represent an enabling material technology for Hyper-X vehicles, where flight weight reduction is a critical requirement.

  3. High-fluence and high-density treatment of perioral rhytides using a new, fractionated 2,790-nm ablative erbium-doped Yttrium Scandium Gallium Garnet Laser.

    Science.gov (United States)

    Ciocon, David H; Hussain, Mussarat; Goldberg, David J

    2011-06-01

    In this study, we evaluated the safety and efficacy of a novel 2,790-nm erbium-doped yttrium scandium gallium garnet (Er:YSGG) laser system for the treatment of facial photodamage and perioral wrinkles using a single-treatment, high-fluence, high-density protocol. Eleven female participants with Fitzpatrick skin types II to III and facial wrinkles underwent a single full-face fractional ablative treatment with a 2,790-nm Er:YSGG laser. Follow-up visits were completed at 1, 2, and 6 weeks 3 and 6 months. Quartile improvement scale (0-4) and Fitzpatrick wrinkle scores (1-9) were used for the assessments. Based on blinded photographic assessments, the mean difference in Fitzpatrick wrinkle scores for full face wrinkles was 1.5 ± 1.2 (a reduction from 6.6 to 5.1; paired t-test, p = .003). There was also a statistically significant mean reduction of 1.7 ± 1.3 in perioral wrinkle scores (from 6.7 to 5.0; p = .002). No serious adverse events were reported. A novel, fractionated, ablative 2,790-nm Er:YSGG laser can safely and effectively treat photodamage and perioral wrinkles in a single treatment using a high-fluence, high-density protocol. Cutera provided the equipment used in this study and funding to Dr. Goldberg. © 2011 by the American Society for Dermatologic Surgery, Inc.

  4. Impact of layer and substrate properties on the surface acoustic wave velocity in scandium doped aluminum nitride based SAW devices on sapphire

    Energy Technology Data Exchange (ETDEWEB)

    Gillinger, M., E-mail: manuel.gillinger@tuwien.ac.at; Knobloch, T.; Schneider, M.; Schmid, U. [Institute of Sensor and Actuator Systems, TU Wien, 1040 Vienna (Austria); Shaposhnikov, K.; Kaltenbacher, M. [Institute of Mechanics and Mechatronics, TU Wien, 1040 Vienna (Austria)

    2016-06-06

    This paper investigates the performance of surface acoustic wave (SAW) devices consisting of reactively sputter deposited scandium doped aluminum nitride (Sc{sub x}Al{sub 1-x}N) thin films as piezoelectric layers on sapphire substrates for wireless sensor or for RF-MEMS applications. To investigate the influence of piezoelectric film thickness on the device properties, samples with thickness ranging from 500 nm up to 3000 nm are fabricated. S{sub 21} measurements and simulations demonstrate that the phase velocity is predominantly influenced by the mass density of the electrode material rather than by the thickness of the piezoelectric film. Additionally, the wave propagation direction is varied by rotating the interdigital transducer structures with respect to the crystal orientation of the substrate. The phase velocity is about 2.5% higher for a-direction compared to m-direction of the sapphire substrate, which is in excellent agreement with the difference in the anisotropic Young's modulus of the substrate corresponding to these directions.

  5. 14 CFR 61.121 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Commercial Pilots § 61.121 Applicability. This subpart prescribes the requirements for the issuance of commercial pilot certificates and ratings, the...

  6. 14 CFR 61.127 - Flight proficiency.

    Science.gov (United States)

    2010-01-01

    ... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Commercial Pilots § 61.127 Flight proficiency. (a) General. A person who applies for a commercial pilot certificate must receive and log ground and...

  7. 10 CFR 61.7 - Concepts.

    Science.gov (United States)

    2010-01-01

    ... radioactive waste and not to other methods such as sea or extraterrestrial disposal. Part 61 contains... institutional control. (3) During the period when the final site closure and stabilization activities are being...

  8. Structure and temperature effects on Nd3+ spectra in polycrystalline mixed scandium aluminum garnets Y3ScxAl5-xO12

    Science.gov (United States)

    Lupei, A.; Lupei, V.; Hau, S.; Gheorghe, C.; Voicu, F.

    2015-09-01

    New spectroscopic data obtained from high resolution low temperature absorption and emission spectra of Nd3+ in mixed scandium aluminum garnets Y3ScxAl5-xO12 - (x = 0-2) translucent ceramics revealed transition dependent composition effects: modification of the shapes (Lorentz at x = 0 and 2, quasi-Gauss at x = 1, x-dependent asymmetric for other x values, with obvious multicenter structure for low x), widths and shifts of the lines. Nd3+ electronic structure dependence on structural changes with composition is analyzed in terms of nephelauxetic effect and maximum splitting of manifolds: Sc3+ co-doping reduces the nephelauxetic effect, and the increase of 4F3/2 splitting from 85 cm-1 (x = 0) to 98 cm-1 (x = 2) denotes the lowering of local symmetry. The multicenter structure and inhomogeneous broadening of Nd3+ lines is attributed to crystal field distributions determined by the random occupancy of the octahedral sites by Sc3+ and Al3+. For low x (0.2) the resolved two satellites S1, S2 that accompany Nd:YAG lines are correlated to anisotropic crystal field perturbations produced by the n.n. Sc3+ by analogy to those determined by Y3+-antisites (excess of Y3+ ions that enter in octahedral sites of the melt-grown YAG crystals). The temperature evolution of the Nd3+ spectral characteristics (line intensity, shift, broadening) in the 10-300 K range is analyzed in terms of thermal population of the Stark levels, of the effect on electron-phonon interaction and on lattice expansion. The relevance of the spectroscopic properties on the laser emission characteristics in these systems is discussed.

  9. Dissolved scandium, yttrium, and lanthanum in the surface waters of the North Atlantic: Potential use as an indicator of scavenging intensity

    Science.gov (United States)

    Till, C. P.; Shelley, R. U.; Landing, W. M.; Bruland, K. W.

    2017-08-01

    Recent work has begun to elucidate the biogeochemical cycling of scandium (Sc) in the open ocean, but so far no surface distribution data have been reported of dissolved Sc, and no basin-scale surface distributions have been reported of yttrium (Y) or lanthanum (La). This work presents basin-wide surface Sc, Y, and La data in a section across the North Atlantic subtropical gyre (2011 GEOTRACES GA03) and investigates the potential utility of these distributions. This work uses dissolved and aerosol concentration data for La and Sc to estimate their surface ocean residence times in both the center of the oligotrophic gyre and near the African coastline. This work additionally shows that the surface distribution of Sc in the North Atlantic correlates with the shape of the gyre as inferred by isotherm depth, with lower Sc concentrations at the gyre boundaries. This pattern suggests that Sc could be drawn down by the elevated particle flux at the gyre boundaries. In this case, Sc removal could be used as an indicator of scavenging intensity. In order to account for variable input of Sc to the surface ocean, we propose normalizing the Sc distribution to that of Y or La, which are much less particle reactive and are input via dust to the surface North Atlantic in constant ratios with Sc. Such normalization improves the correlation with isotherm depth. We propose that the variations in dissolved Y/Sc and La/Sc ratios may be due to preferential Sc scavenging and could therefore indicate scavenging intensity.

  10. On new ternary equiatomic scandium transition metal aluminum compounds ScTAl with T = Cr, Ru, Ag, Re, Pt, and Au

    Energy Technology Data Exchange (ETDEWEB)

    Radzieowski, Mathis; Janka, Oliver [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Benndorf, Christopher [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Haverkamp, Sandra [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Eckert, Hellmut [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; University of Sao Paulo, Sao Carlos, SP (Brazil). Inst. of Physics

    2016-08-01

    The new equiatomic scandium transition metal aluminides ScTAl for T = Cr, Ru, Ag, Re, Pt, and Au were obtained by arc-melting of the elements followed by subsequent annealing for crystal growth. The samples were studied by powder and single crystal X-ray diffraction. The structures of three compounds were refined from single crystal X-ray diffractometer data: ScCrAl, MgZn{sub 2} type, P6{sub 3}/mmc, a = 525.77(3), c = 858.68(5) pm, R{sub 1} = 0.0188, wR{sub 2} = 0.0485, 204 F{sup 2} values, 13 variables, ScPtAl, TiNiSi type, Pnma, a = 642.83(4), b = 428.96(2), c = 754.54(5) pm, R{sub 1} = 0.0326, wR{sub 2} = 0.0458, 448 F{sup 2} values, 20 variables and ScAuAl, HfRhSn type, P anti 62c, a = 722.88(4), c = 724.15(4) pm, R{sub 1} = 0.0316, wR{sub 2} = 0.0653, 512 F{sup 2} values, 18 variables. Phase pure samples of all compounds were furthermore investigated by magnetic susceptibility measurements, and Pauli-paramagnetism but no superconductivity was observed down to 2.1 K for all of them. The local structural features and disordering phenomena have been characterized by {sup 27}Al and {sup 45}Sc magic angle spinning (MAS) and static NMR spectroscopic investigations.

  11. Treatment of infraorbital dark circles in atopic dermatitis with a 2790-nm erbium: yttrium scandium gallium garnet laser: a pilot study.

    Science.gov (United States)

    Park, Kui Young; Oh, In Young; Moon, Nam Ju; Seo, Seong Jun

    2013-04-01

    Although many Asian atopic patients have orbital darkening symptom and the demand to treat this condition is increasing, little has been reported in the literature on the treatment of infraorbital dark circles in atopic dermatitis. To evaluate the clinical efficacy and safety of 2790-nm erbium:yttrium scandium gallium garnet (Er:YSGG) laser therapy for reducing infraorbital dark circles in atopic dermatitis patients. Ten Korean patients over 21 year with mild atopic dermatitis and infraorbital dark circles were enrolled in this study. Patients who need active atopic dermatitis treatments are excluded because of the possibility of aggravation after laser treatment. They were treated for dark circles using a 2790-nm Er:YSGG laser. The treatment parameters were 1.8-2.2 J/cm² fluence, 6-mm spot size, and 0.3-ms pulse width with 10% overlap over the infraorbital areas once with a 4-week interval between treatments. Efficacy was assessed with a quartile grading score ranging from 0 to 5 by a blinded investigator, and the patients also documented their degree of satisfaction with the same grading score. All possible side effects were evaluated. The clinical assessment showed 74.5% (2.7) and 72.5% (2.5) improvements, and the patient satisfaction scale scores improved an average of 74% (2.4) and 71.5% (2.3) at 2 months and 4 months after treatment, respectively. There were no severe side effects or aggravation of atopic dermatitis. Our study suggests that 2790-nm Er:YSGG laser therapy can be effectively and safely used in the treatment of infraorbital dark circles in atopic dermatitis patients.

  12. The influence of cation ordering, oxygen vacancy distribution and proton siting on observed properties in ceramic electrolytes: the case of scandium substituted barium titanate.

    Science.gov (United States)

    Torino, Nico; Henry, Paul F; Knee, Christopher S; Bjørheim, Tor Svendsen; Rahman, Seikh M H; Suard, Emma; Giacobbe, Carlotta; Eriksson, Sten G

    2017-07-04

    The origin of the 2-order of magnitude difference in the proton conductivity of the hydrated forms of hexagonal and cubic oxygen deficient BaScxTi1-xO3-δ (x = 0.2 and x = 0.7) was probed using a combination of neutron diffraction and density functional theory techniques to support published X-ray diffraction, conductivity, thermogravimetric and differential scanning calorimetry studies. Cation ordering is found in the 6H structure type (space group P63/mmc) adopted by BaSc0.2Ti0.8O3-δ with scandium preferentially substituting in the vertex sharing octahedra (2a crystallographic site) and avoiding the face-sharing octahedra (4f site). This is coupled with oxygen vacancy ordering in the central plane of the face-sharing octahedra (O1 site). In BaSc0.7Ti0.3O3-δ a simple cubic perovskite (space group Pm3[combining macron]m) best represents the average structure from Rietveld analysis with no evidence of either cation ordering or oxygen vacancy ordering. Significant diffuse scattering is observed, indicative of local order. Hydration in both cases leads to complete filling of the available oxygen vacancies and permits definition of the proton sites. We suggest that the more localised nature of the proton sites in the 6H structure is responsible for the significantly lower proton conduction observed in the literature. Within the 6H structure type final model, proton diffusion requires a 3-step process via higher energy proton sites that are unoccupied at room temperature and is also likely to be anisotropic whereas the highly disordered cubic perovskite proton position allows 3-dimensional diffusion by well-described modes. Finally, we propose how this knowledge can be used to further materials design for ceramic electrolytes for proton conducting fuel cells.

  13. 40 CFR 61.357 - Reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... Operations § 61.357 Reporting requirements. (a) Each owner or operator of a chemical plant, petroleum refinery, coke by-product recovery plant, and any facility managing wastes from these industries shall... in the control device is not regenerated at the predetermined carbon bed regeneration time. (I) Each...

  14. 14 CFR 61.129 - Aeronautical experience.

    Science.gov (United States)

    2010-01-01

    ...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Commercial Pilots § 61.129... section, a person who applies for a commercial pilot certificate with an airplane category and single... provided in paragraph (i) of this section, a person who applies for a commercial pilot certificate with an...

  15. 14 CFR 61.125 - Aeronautical knowledge.

    Science.gov (United States)

    2010-01-01

    ...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Commercial Pilots § 61.125 Aeronautical knowledge. (a) General. A person who applies for a commercial pilot certificate must receive and... chapter that relate to commercial pilot privileges, limitations, and flight operations; (2) Accident...

  16. 22 CFR 61.1 - Purpose.

    Science.gov (United States)

    2010-04-01

    ... DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.1... educational, scientific and cultural audio-visual materials between nations by providing favorable import... issuance or authentication of a certificate that the audio-visual material for which favorable treatment is...

  17. 50 CFR 20.61 - Importation limits.

    Science.gov (United States)

    2010-10-01

    ... Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR (CONTINUED... PLANTS (CONTINUED) MIGRATORY BIRD HUNTING Importations § 20.61 Importation limits. No person shall import... wildlife authorities on the first day he hunts in Mexico, he may import the applicable Mexican possession...

  18. 27 CFR 4.61 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... disseminated by mail, whether it appears in a newspaper, magazine, trade booklet, menu, wine card, leaflet... THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Advertising of Wine § 4.61 Definitions. As used... or other reading material (i.e., news release) in any periodical or publication or newspaper for the...

  19. 14 CFR 61.185 - Aeronautical knowledge.

    Science.gov (United States)

    2010-01-01

    ... Flight Instructors With a Sport Pilot Rating § 61.185 Aeronautical knowledge. (a) A person who is..., including: (i) The learning process; (ii) Elements of effective teaching; (iii) Student evaluation and... person employed as a teacher at an accredited college or university. ...

  20. 40 CFR 415.61 - Specialized definitions.

    Science.gov (United States)

    2010-07-01

    ... STANDARDS INORGANIC CHEMICALS MANUFACTURING POINT SOURCE CATEGORY Chlor-alkali Subcategory (Chlorine and Sodium or Potassium Hydroxide Production) § 415.61 Specialized definitions. For the purpose of this subpart: (a) Except as provided below, the general definitions, abbreviations and methods of analysis set...

  1. 14 CFR 61.167 - Privileges.

    Science.gov (United States)

    2010-01-01

    ... debriefings, an airline transport pilot may not instruct in aircraft, flight simulators, and flight training... CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Airline Transport Pilots § 61.167 Privileges. (a) A person who holds an airline transport pilot certificate is entitled to the same privileges as a...

  2. 40 CFR 61.70 - Reporting.

    Science.gov (United States)

    2010-07-01

    ... EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Vinyl Chloride § 61.70... the vinyl chloride content of emissions for each 3-hour period during which average emissions are in...) In polyvinyl chloride plants for which a stripping operation is used to attain the emission level...

  3. 40 CFR 61.209 - Required records.

    Science.gov (United States)

    2010-07-01

    ... used to determine average radium-226 concentration pursuant to § 61.207, including all measurements... sufficient to allow an independent auditor to verify the accuracy of the radium-226 concentration. (c) Each... phosphogypsum. (2) A description of each use of phosphogypsum, including the handling and processing that the...

  4. 19 CFR 151.61 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... (CONTINUED) EXAMINATION, SAMPLING, AND TESTING OF MERCHANDISE Wool and Hair § 151.61 Definitions. The following are general definitions for the purposes of this subpart: (a) Clean kg. ‘Clean kg’ means kilograms of clean yield as defined in paragraph (b) of this section. (b) Clean yield. Except for the purposes...

  5. Recent optical variability in LSI +61 303

    NARCIS (Netherlands)

    Lewis, F.; Russell, D.M.; Rea, N.; Roche, P.; Clark, S.

    2008-01-01

    We have been monitoring the optical counterpart of the TeV emitting binary LSI +61 303 (V615 Cas) since November 2005 with the Faulkes Telescope North (on Haleakala, Maui), as part of a program to monitor long-term variability in X-ray binaries. Prompted by the recent SGR-like burst observed from a

  6. 16 CFR 1616.61 - Enforcement policy.

    Science.gov (United States)

    2010-01-01

    ... FLAMMABILITY OF CHILDREN'S SLEEPWEAR: SIZES 7 THROUGH 14 (FF 5-74) Interpretations and Policies § 1616.61...'s sleepwear in sizes 7 through 14 (including garments and fabric or related material intended or promoted for use in such children's sleepwear) are subject to the Standard FF 5-74 (subpart A of this part...

  7. 38 CFR 17.61 - Eligibility.

    Science.gov (United States)

    2010-07-01

    ... or VA medical center, domiciliary, or nursing home care; or (2) Such care or services were furnished... Residential Care § 17.61 Eligibility. VA health care personnel may assist a veteran by referring such veteran for placement in a privately or publicly-owned community residential care facility if: (a) At the time...

  8. 48 CFR 9904.407-61 - Interpretation. [Reserved

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.407-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.407-61 Interpretation. ...

  9. 48 CFR 9904.405-61 - Interpretation. [Reserved

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.405-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.405-61 Interpretation. ...

  10. 48 CFR 9904.409-61 - Interpretation. [Reserved

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.409-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.409-61 Interpretation. ...

  11. 48 CFR 9904.408-61 - Interpretation. [Reserved

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.408-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.408-61 Interpretation. ...

  12. 48 CFR 9904.410-61 - Interpretation. [Reserved

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.410-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.410-61 Interpretation. ...

  13. 48 CFR 9904.404-61 - Interpretation. [Reserved

    Science.gov (United States)

    2010-10-01

    ...-61 Section 9904.404-61 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET PROCUREMENT PRACTICES AND COST ACCOUNTING STANDARDS COST ACCOUNTING STANDARDS 9904.404-61 Interpretation. ...

  14. Effects of erbium-and chromium-doped yttrium scandium gallium garnet and diode lasers on the surfaces of restorative dental materials: a scanning electron microscope study.

    Science.gov (United States)

    Hatipoglu, M; Barutcigil, C

    2015-01-01

    The aim of this study is to evaluate the potential effects of laser irradiation, which is commonly performed in periodontal surgery, on the surfaces of restorative materials. Five different restorative dental materials were used in this study, as follows: (1) Resin composite, (2) poly acid-modified resin composite (compomer), (3) conventional glass ionomer cement (GIC), (4) resin-modified glass ionomer cement (RMGIC), and (5) amalgam. Four cylindrical samples (8 mm diameter, 2 mm height) were prepared for each restorative material. In addition, four freshly extracted, sound human incisors teeth were selected. Two different laser systems commonly used in periodontal surgery were examined in this study: A 810 nm diode laser at a setting of 1 W with continuous-phase laser irradiation for 10 s, and an erbium-and chromium-doped yttrium scandium gallium garnet (Er, Cr: YSGG) laser at settings of 2.5 W, 3.25 W, and 4 W with 25 Hz laser irradiation for 10 s. Scanning electron microscopy (SEM) analysis was performed to evaluate the morphology and surface deformation of the restorative materials and tooth surfaces. According to the SEM images, the Er, Cr: YSGG laser causes irradiation markings that appear as demineralized surfaces on tooth samples. The Er, Cr: YSGG laser also caused deep defects on composite, compomer, and RMGIC surfaces because of its high power, and the ablation was deeper for these samples. High-magnification SEM images of GIC samples showed the melting and combustion effects of the Er, Cr: YSGG laser, which increased as the laser power was increased. In amalgam samples, neither laser left significant harmful effects at the lowest power setting. The diode laser did cause irradiation markings, but they were insignificant compared with those left by the Er, Cr: YSGG laser on the surfaces of the different materials and teeth. Within the limitations of this study, it can be concluded that Er, Cr: YSGG laser irradiation could cause distortions of the surfaces

  15. Report from the NA61/SHINE experiment

    CERN Document Server

    Aduszkiewicz, A

    2015-01-01

    This document reports on the status and plans of the NA61/SHINE experiment at the CERN SPS as of October 2015. First, an overview of the 2014 and 2015 data-taking period on p+Pb interactions at 158 GeV/c and Ar+Sc collisions at 13A GeV/c - 150A GeV/c is given. The latter data-taking with the first primary Ar beams at CERN was a major success. Second, the facility maintenance and upgrades are briefly presented. The VTX-1 magnet was damaged at the beginning of the 2015 proton period. The physics data-taking for p+p interactions at 400 GeV/c and for the Fermilab neutrino beams as well as the pilot data taking on Pb+Pb collisions at 30A GeV/c was replaced by detector tests and calibration runs. Third, the advance in the NA61/SHINE software and calibration procedures is briefly reported. Fourth, new physics results are presented. In particular, the very first results on Ar+Sc collisions are presented. Fifth, plans for data taking in 2016 - 2018 are outlined and ideas concerning the NA61/SHINE physics programme...

  16. 46 CFR 61.05-20 - Boiler safety valves.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Boiler safety valves. 61.05-20 Section 61.05-20 Shipping... INSPECTIONS Tests and Inspections of Boilers § 61.05-20 Boiler safety valves. Each safety valve for a drum, superheater, or reheater of a boiler shall be tested at the interval specified by table 61.05-10. ...

  17. Influence of c-axis orientation and scandium concentration on infrared active modes of magnetron sputtered Sc{sub x}Al{sub 1−x}N thin films

    Energy Technology Data Exchange (ETDEWEB)

    Mayrhofer, P. M.; Bittner, A.; Schmid, U. [Institute of Sensor and Actuator Systems, Vienna University of Technology, Floragasse 7, 1040 Vienna (Austria); Eisenmenger-Sittner, C. [Institute of Solid State Physics, Vienna University of Technology, Wiedner Hauptstrasse 8, 1040 Vienna (Austria); Euchner, H. [Institute of Materials Science and Technology, Vienna University of Technology, Karlsplatz 13, 1040 Vienna (Austria)

    2013-12-16

    Doping of wurtzite aluminium nitride (AlN) with scandium (Sc) significantly enhances the piezoelectric properties of AlN. Sc{sub x}Al{sub 1−x}N thin films with different Sc concentrations (x = 0 to 0.15) were deposited by DC reactive magnetron sputtering. Infrared (IR) absorbance spectroscopy was applied to investigate the Sc concentration dependent shift of the IR active modes E{sub 1}(TO) and A{sub 1}(TO). These results are compared to ab initio simulations, being in excellent agreement with the experimental findings. In addition, IR spectroscopy is established as an economical and fast method to distinguish between thin films with a high degree of c-axis orientation and those exhibiting mixed orientations.

  18. SUBTASK 6.1 – STRATEGIC STUDIES

    Energy Technology Data Exchange (ETDEWEB)

    Erickson, Thomas; Harju, John; Steadman, Edward; Holmes, Michael

    2015-05-31

    The Energy & Environmental Research Center (EERC) has recently completed 7 years of research through the Cooperative Agreement with the U.S. Department of Energy (DOE) National Energy Technology Laboratory (NETL) focused on fossil energy technology development and demonstration. To support a significant number of the different activities being considered within all of our research contracts with NETL, a subtask (6.1 – Strategic Studies) was created to focus on small research efforts that came up throughout the year that would support an existing EERC–NETL project or would help to develop a new concept for inclusion in future efforts. This subtask was funded through the EERC–DOE Joint Program on Research and Development for Fossil Energy-Related Resources Cooperative Agreement No. DE-FC26- 08NT43291

  19. Recent results from NA61/SHINE

    CERN Document Server

    Andronov, Evgeny

    2016-01-01

    The NA61/SHINE experiment aims to discover the critical point of strongly interacting matter and study the properties of the onset of deconfinement. For these goals a scan of the two dimensional phase diagram (T-$\\mu_B$) is being performed at the SPS by measurements of hadron production in proton-proton, proton-nucleus and nucleus-nucleus interactions as a function of collision energy and system size. In this contribution intriguing results on the energy dependence of hadron spectra and yields in inelastic p+p and centrality selected Be+Be collisions will be presented. In particular, the energy dependence of the signals of deconfinement, the 'horn', 'step' and 'kink', in p+p interactions will be presented and compared with the corresponding results from central Pb+Pb collisions from NA49.

  20. Private and Commercial Pilot: Gyroplane. Flight Test Guide, Part 61 Revised 1973, AC 61-60.

    Science.gov (United States)

    Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

    This flight test guide assists the applicant and his instructor in preparing for the Private or Commercial Pilot Rotocraft Certificate with Gyroplane Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information concerning pilot operations, procedures, and maneuvers relevant to the flight test required for these…

  1. Commercial Pilot; Airplane. Flight Test Guide, Part 61 Revised, AC 61-55.

    Science.gov (United States)

    Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

    This flight test guide assists the applicant and his instructor in preparing for the Commercial Pilot Certificate with Airplane Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information concerning pilot operations, procedures, and maneuvers relevant to the flight test required for the certificate. Preflight duties,…

  2. Private and Commercial Pilot; Heliocoptor. Flight Test Guide, Part 61 Revised, AC 61-59.

    Science.gov (United States)

    Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

    This flight test guide assists the applicant and his instructor in preparing for the Private or Commercial Pilot Rotocraft Certificate with Helicopter Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information and guidance concerning the pilot operations, procedures, and maneuvers relevant to the flight test required…

  3. 7 CFR 989.61 - Above parity situations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Above parity situations. 989.61 Section 989.61 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing...) of the act. Trade Practices ...

  4. 7 CFR 1005.61 - Computation of uniform prices.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Computation of uniform prices. 1005.61 Section 1005.61... Regulating Handling Uniform Prices § 1005.61 Computation of uniform prices. On or before the 11th day of each... in the computation of these prices, and such handler's report shall not be included in the...

  5. 7 CFR 1007.61 - Computation of uniform prices.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Computation of uniform prices. 1007.61 Section 1007.61... Handling Uniform Prices § 1007.61 Computation of uniform prices. On or before the 11th day of each month... computation of these prices, and such handler's report shall not be included in the computation for succeeding...

  6. 7 CFR 1131.61 - Computation of uniform prices.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Computation of uniform prices. 1131.61 Section 1131.61... Handling Uniform Prices § 1131.61 Computation of uniform prices. On or before the 11th day of each month... computation of these prices, and such handler's report shall not be included in the computation for succeeding...

  7. 7 CFR 1006.61 - Computation of uniform prices.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 9 2010-01-01 2009-01-01 true Computation of uniform prices. 1006.61 Section 1006.61... Handling Uniform Prices § 1006.61 Computation of uniform prices. On or before the 11th day of each month... computation of these prices, and such handler's report shall not be included in the computation for succeeding...

  8. 10 CFR 61.32 - Facility information and verification.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Facility information and verification. 61.32 Section 61.32... WASTE Licenses Us/iaea Safeguards Agreement § 61.32 Facility information and verification. (a) In... license shall submit facility information, as described in § 75.10 of this chapter, on Form N-71 and...

  9. 34 CFR 674.61 - Discharge for death or disability.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Discharge for death or disability. 674.61 Section 674.61 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION FEDERAL PERKINS LOAN PROGRAM Loan Cancellation § 674.61...

  10. 38 CFR 61.31 - Application for per diem.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Application for per diem. 61.31 Section 61.31 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.31 Application for per diem. (a) To apply for...

  11. 38 CFR 61.60 - Notice of Fund Availability.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Notice of Fund Availability. 61.60 Section 61.60 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.60 Notice of Fund Availability. When funds...

  12. 38 CFR 61.55 - Technical assistance reports.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Technical assistance reports. 61.55 Section 61.55 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.55 Technical assistance reports. Each...

  13. 46 CFR 61.05-15 - Boiler mountings and attachments.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Boiler mountings and attachments. 61.05-15 Section 61.05... TESTS AND INSPECTIONS Tests and Inspections of Boilers § 61.05-15 Boiler mountings and attachments. (a....05-10. (b) Each stud or bolt for each boiler mounting that paragraph (c) of this section requires to...

  14. 19 CFR 123.61 - Baggage arriving in baggage car.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Baggage arriving in baggage car. 123.61 Section 123.61 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY CUSTOMS RELATIONS WITH CANADA AND MEXICO Baggage § 123.61 Baggage arriving in baggage...

  15. 50 CFR 14.61 - Import declaration requirements.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 1 2010-10-01 2010-10-01 false Import declaration requirements. 14.61 Section 14.61 Wildlife and Fisheries UNITED STATES FISH AND WILDLIFE SERVICE, DEPARTMENT OF THE INTERIOR... PLANTS IMPORTATION, EXPORTATION, AND TRANSPORTATION OF WILDLIFE Wildlife Declarations § 14.61 Import...

  16. 46 CFR 61.15-5 - Steam piping.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Steam piping. 61.15-5 Section 61.15-5 Shipping COAST... Periodic Tests of Piping Systems § 61.15-5 Steam piping. (a) Main steam piping shall be subjected to a... removed and the piping thoroughly examined. (b) All steam piping subject to pressure from the main boiler...

  17. 10 CFR 61.81 - Tests at land disposal facilities.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Tests at land disposal facilities. 61.81 Section 61.81 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND DISPOSAL OF RADIOACTIVE WASTE Records, Reports, Tests, and Inspections § 61.81 Tests at land disposal facilities. (a) Each...

  18. 34 CFR 6.1 - Publication or patenting of inventions.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Publication or patenting of inventions. 6.1 Section 6.1 Education Office of the Secretary, Department of Education INVENTIONS AND PATENTS (GENERAL) § 6.1 Publication or patenting of inventions. It is the general policy of the Department that the results of...

  19. 42 CFR 61.20 - Inventions or discoveries.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Inventions or discoveries. 61.20 Section 61.20..., TRAINING FELLOWSHIPS Regular Fellowships § 61.20 Inventions or discoveries. Any fellowship award made... inventions or discoveries shall be maintained for such periods, and filed with or otherwise made available to...

  20. 25 CFR 700.61 - Fair market value.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Fair market value. 700.61 Section 700.61 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES General Policies and Instructions Definitions § 700.61 Fair market value. Fair market value shall mean the value...

  1. 42 CFR 61.19 - Copyright and reproduction.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Copyright and reproduction. 61.19 Section 61.19..., TRAINING FELLOWSHIPS Regular Fellowships § 61.19 Copyright and reproduction. Where the work accomplished... copyright the work, but the Public Health Service reserves a royalty-free, nonexclusive, and irrevocable...

  2. 26 CFR 1.61-1 - Gross income.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Gross income. 1.61-1 Section 1.61-1 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Definition of Gross Income, Adjusted Gross Income, and Taxable Income § 1.61-1 Gross...

  3. 40 CFR 66.61 - Duty to pay.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Duty to pay. 66.61 Section 66.61... COLLECTION OF NONCOMPLIANCE PENALTIES BY EPA Payment § 66.61 Duty to pay. (a) Except where the owner or... who submits a petition pursuant to § 66.52 shall pay the penalty amount calculated by the owner or...

  4. 21 CFR 201.61 - Statement of identity.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Statement of identity. 201.61 Section 201.61 Food...: GENERAL LABELING Labeling Requirements for Over-the-Counter Drugs § 201.61 Statement of identity. (a) The... features a statement of the identity of the commodity. (b) Such statement of identity shall be in terms of...

  5. 21 CFR 801.61 - Statement of identity.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Statement of identity. 801.61 Section 801.61 Food... DEVICES LABELING Labeling Requirements for Over-the-Counter Devices § 801.61 Statement of identity. (a... principal features a statement of the identity of the commodity. (b) Such statement of identity shall be in...

  6. 10 CFR 35.61 - Calibration of survey instruments.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Calibration of survey instruments. 35.61 Section 35.61... § 35.61 Calibration of survey instruments. (a) A licensee shall calibrate the survey instruments used... or decade that will be used to show compliance; and (3) Conspicuously note on the instrument the date...

  7. 47 CFR 61.25 - References to other instruments.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false References to other instruments. 61.25 Section 61.25 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) TARIFFS General Rules for Nondominant Carriers § 61.25 References to other instruments. In...

  8. 38 CFR 61.54 - Awarding technical assistance grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Awarding technical assistance grants. 61.54 Section 61.54 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.54 Awarding technical assistance grants. (a...

  9. 38 CFR 61.16 - Matching funds for capital grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Matching funds for capital grants. 61.16 Section 61.16 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.16 Matching funds for capital grants. The...

  10. 38 CFR 61.40 - Special needs grants-general.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Special needs grants-general. 61.40 Section 61.40 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.40 Special needs grants—general. (a) VA...

  11. 38 CFR 61.50 - Technical assistance grants-general.

    Science.gov (United States)

    2010-07-01

    ... grants-general. 61.50 Section 61.50 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS... relating to the provision of assistance for homeless veterans. The recipients are to use the grants to... assistance to homeless veterans in order to help such groups apply for grants under 38 CFR part 61 or apply...

  12. 38 CFR 61.51 - Applications for technical assistance grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Applications for technical assistance grants. 61.51 Section 61.51 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.51 Applications for...

  13. 38 CFR 61.41 - Special needs grants application.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Special needs grants application. 61.41 Section 61.41 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.41 Special needs grants application. (a) To...

  14. 38 CFR 61.17 - Site control for capital grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Site control for capital grants. 61.17 Section 61.17 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.17 Site control for capital grants. (a) As...

  15. 38 CFR 61.14 - Selecting applications for capital grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Selecting applications for capital grants. 61.14 Section 61.14 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.14 Selecting applications for...

  16. 38 CFR 61.44 - Awarding special needs grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Awarding special needs grants. 61.44 Section 61.44 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.44 Awarding special needs grants. (a...

  17. 20 CFR 617.61 - Information, reports, and studies.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Information, reports, and studies. 617.61 Section 617.61 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR TRADE ADJUSTMENT ASSISTANCE FOR WORKERS UNDER THE TRADE ACT OF 1974 Administration by Applicable State Agencies § 617.61 Information, reports, and studies. A...

  18. 31 CFR 315.61 - Payment after death.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment after death. 315.61 Section 315.61 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL..., Absentees, et al. § 315.61 Payment after death. After the death of the ward, and at any time prior to the...

  19. 47 CFR 61.46 - Adjustments to the API.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Adjustments to the API. 61.46 Section 61.46... Rules for Dominant Carriers § 61.46 Adjustments to the API. (a) Except as provided in paragraphs (d) and... carrier must calculate an API for each affected basket pursuant to the following methodology: APIt = APIt...

  20. 49 CFR 38.61 - Public information system.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Public information system. 38.61 Section 38.61... SPECIFICATIONS FOR TRANSPORTATION VEHICLES Rapid Rail Vehicles and Systems § 38.61 Public information system. (a... other passenger information. Alternative systems or devices which provide equivalent access are also...

  1. 40 CFR 61.152 - Air-cleaning.

    Science.gov (United States)

    2010-07-01

    ... HEPA filter that is certified to be at least 99.97 percent efficient for 0.3 micron particles. (3) The...(c)(1)(ii), 61.150(a)(1)(ii), 61.150(a)(2)(ii), and 61.155(e) shall: (1) Use fabric filter collection... filter collection devices installed after January 10, 1989, provide for easy inspection for faulty bags...

  2. 40 CFR 61.55 - Monitoring of emissions and operations.

    Science.gov (United States)

    2010-07-01

    ... period, demonstrated either by stack sampling according to § 61.53 or sludge sampling according to § 61...-alkali plants—hydrogen and end-box ventilation gas streams. (1) The owner or operator of each mercury... emission test that demonstrates compliance with the emission limits in § 61.52, on the hydrogen stream by...

  3. 7 CFR 61.31 - License must be posted.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false License must be posted. 61.31 Section 61.31 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Cottonseed Samplers § 61.31 License must be posted. Each licensed sampler shall keep his license...

  4. 30 CFR 7.61 - Purpose and effective date.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Purpose and effective date. 7.61 Section 7.61... APPROVAL OF MINING PRODUCTS TESTING BY APPLICANT OR THIRD PARTY Multiple-Shot Blasting Units § 7.61 Purpose and effective date. This subpart establishes the specific requirements for MSHA approval of multiple...

  5. 45 CFR 1801.61 - Termination of scholarship.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Termination of scholarship. 1801.61 Section 1801.61 Public Welfare Regulations Relating to Public Welfare (Continued) HARRY S. TRUMAN SCHOLARSHIP FOUNDATION HARRY S. TRUMAN SCHOLARSHIP PROGRAM Duration of Scholarship § 1801.61 Termination of scholarship...

  6. 46 CFR 61.15-12 - Nonmetallic expansion joints.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Nonmetallic expansion joints. 61.15-12 Section 61.15-12... INSPECTIONS Periodic Tests of Piping Systems § 61.15-12 Nonmetallic expansion joints. (a) Nonmetallic expansion joints must be examined externally at each inspection for certification and periodic inspection...

  7. 45 CFR 2400.61 - Postponement of award.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Postponement of award. 2400.61 Section 2400.61... FOUNDATION FELLOWSHIP PROGRAM REQUIREMENTS Special Conditions § 2400.61 Postponement of award. Upon application to the Foundation, a Fellow may seek postponement of his or her fellowship because of ill health...

  8. 7 CFR 1209.61 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1209.61 Section 1209.61..., Books and Records § 1209.61 Books and records. Each persons who is subject to this subpart shall maintain and make available for inspection by the Council or the Secretary such books and records as are...

  9. 7 CFR 1216.61 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1216.61 Section 1216.61... INFORMATION ORDER Peanut Promotion, Research, and Information Order Reports, Books, and Records § 1216.61 Books and records. Each first handler and producer subject to this subpart shall maintain and make...

  10. 7 CFR 1219.61 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1219.61 Section 1219.61..., AND INFORMATION Hass Avocado Promotion, Research, and Information Order Books, Records, and Reports § 1219.61 Books and records. Each producer, first handler, and importer subject to this subpart shall...

  11. 7 CFR 1218.61 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1218.61 Section 1218.61..., AND INFORMATION ORDER Blueberry Promotion, Research, and Information Order Reports, Books, and Records § 1218.61 Books and records. Each first handler, producer, and importer subject to this subpart shall...

  12. 7 CFR 1215.61 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1215.61 Section 1215.61... CONSUMER INFORMATION Popcorn Promotion, Research, and Consumer Information Order Reports, Books, and Records § 1215.61 Books and records. Each person who is subject to this subpart shall maintain and make...

  13. 7 CFR 1206.61 - Books and records.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Books and records. 1206.61 Section 1206.61... INFORMATION Mango Promotion, Research, and Information Order Definitions Reports, Books, and Records § 1206.61 Books and records. Each first handler and importer shall maintain and make available for inspection by...

  14. 42 CFR 2.61 - Legal effect of order.

    Science.gov (United States)

    2010-10-01

    ... OF ALCOHOL AND DRUG ABUSE PATIENT RECORDS Court Orders Authorizing Disclosure and Use § 2.61 Legal effect of order. (a) Effect. An order of a court of competent jurisdiction entered under this subpart is... 42 Public Health 1 2010-10-01 2010-10-01 false Legal effect of order. 2.61 Section 2.61 Public...

  15. 40 CFR 87.61 - Turbine fuel specifications.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Turbine fuel specifications. 87.61 Section 87.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS... Gaseous Emissions (Aircraft and Aircraft Gas Turbine Engines) § 87.61 Turbine fuel specifications. For...

  16. 7 CFR 61.34 - Drawing and preparation of sample.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Drawing and preparation of sample. 61.34 Section 61.34 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Cottonseed Samplers § 61.34 Drawing and preparation of sample. Each licensed cottonseed sampler shall draw...

  17. 14 CFR 23.61 - Takeoff flight path.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Takeoff flight path. 23.61 Section 23.61... STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Flight Performance § 23.61 Takeoff flight path. For each commuter category airplane, the takeoff flight path must be determined as follows...

  18. 46 CFR 61.20-1 - Steering gear.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Steering gear. 61.20-1 Section 61.20-1 Shipping COAST... Periodic Tests of Machinery and Equipment § 61.20-1 Steering gear. (a) The marine inspector must inspect the steering gear at each inspection for certification for vessels whose Certificate of Inspections...

  19. Analysis list: Wdr61 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Wdr61 Muscle + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Wdr61.1.ts...v http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Wdr61.5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/Wdr...61.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Wdr61.Muscle.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Muscle.gml ...

  20. Two scandium-biuret complexes: [Sc(C2H5N3O2)(H2O)5]Cl3 x H2O and [Sc(C2H5N3O2)4](NO3)3.

    Science.gov (United States)

    Harrison, William T A

    2008-05-01

    The scandium(III) cations in the structures of pentaaqua(biuret-kappa(2)O,O')scandium(III) trichloride monohydrate, [Sc(C(2)H(5)N(3)O(2))(H(2)O)(5)]Cl(3) x H(2)O, (I), and tetrakis(biuret-kappa(2)O,O')scandium(III) trinitrate, [Sc(C(2)H(5)N(3)O(2))(4)](NO(3))(3), (II), are found to adopt very different coordinations with the same biuret ligand. The roles of hydrogen bonding and the counter-ion in the establishment of the structures are described. In (I), the Sc(3+) cation adopts a fairly regular pentagonal bipyramidal coordination geometry arising from one O,O'-bidentate biuret molecule and five water molecules. A dense network of N-H...Cl, O-H...O and O-H...Cl hydrogen bonds help to establish the packing, resulting in dimeric associations of two cations and two water molecules. In (II), the Sc(3+) cation (site symmetry 2) adopts a slightly squashed square-antiprismatic geometry arising from four O,O'-bidentate biuret molecules. A network of N-H...O hydrogen bonds help to establish the packing, which features [010] chains of cations. One of the nitrate ions is disordered about an inversion centre. Both structures form three-dimensional hydrogen-bond networks.

  1. 45 CFR 61.4 - How information must be reported.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false How information must be reported. 61.4 Section 61.4 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND...

  2. 45 CFR 61.2 - Applicability of these regulations.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Applicability of these regulations. 61.2 Section 61.2 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND...

  3. 45 CFR 61.5 - When information must be reported.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false When information must be reported. 61.5 Section 61.5 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND...

  4. 38 CFR 61.30 - Per diem-general.

    Science.gov (United States)

    2010-07-01

    ... HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.30 Per diem-general. VA provides per diem funds to... of supportive housing or services after November 10, 1992 so they can assist homeless veterans by... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Per diem-general. 61.30...

  5. 29 CFR 96.61 - Purpose and scope of subpart.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Purpose and scope of subpart. 96.61 Section 96.61 Labor Office of the Secretary of Labor AUDIT REQUIREMENTS FOR GRANTS, CONTRACTS, AND OTHER AGREEMENTS Appeals... audit resolution as a result of audits. (b) Subrecipients and subcontractors shall have only such appeal...

  6. 14 CFR 437.61 - Landing and impact locations.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Landing and impact locations. 437.61 Section 437.61 Aeronautics and Space COMMERCIAL SPACE TRANSPORTATION, FEDERAL AVIATION ADMINISTRATION... that— (a) Is big enough to contain an impact, including debris dispersion upon impact; and (b) At the...

  7. 7 CFR 3015.61 - Financial management standards.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Financial management standards. 3015.61 Section 3015... Management Systems § 3015.61 Financial management standards. The following standards shall be met by recipients and subrecipients in managing their financial management system. (a) Financial reporting. Complete...

  8. 40 CFR 761.61 - PCB remediation waste.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false PCB remediation waste. 761.61 Section... PROHIBITIONS Storage and Disposal § 761.61 PCB remediation waste. This section provides cleanup and disposal options for PCB remediation waste. Any person cleaning up and disposing of PCBs managed under this section...

  9. 34 CFR 366.61 - What are the compliance indicators?

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false What are the compliance indicators? 366.61 Section 366.61 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION CENTERS FOR INDEPENDENT LIVING Evaluation...

  10. 7 CFR 1794.61 - Environmental impact statement.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 12 2010-01-01 2010-01-01 false Environmental impact statement. 1794.61 Section 1794..., DEPARTMENT OF AGRICULTURE (CONTINUED) ENVIRONMENTAL POLICIES AND PROCEDURES Procedure for Environmental Impact Statements § 1794.61 Environmental impact statement. An EIS shall be prepared in accordance with...

  11. 7 CFR 61.1 - Words in singular form.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Words in singular form. 61.1 Section 61.1 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Words in singular form. Words used in the regulations in this subpart in the singular form shall be...

  12. 40 CFR 61.142 - Standard for asbestos mills.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standard for asbestos mills. 61.142... (CONTINUED) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS National Emission Standard for Asbestos § 61.142 Standard for asbestos mills. (a) Each owner or operator of an asbestos mill shall either...

  13. 27 CFR 53.61 - Imposition and rates of tax.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Imposition and rates of tax. 53.61 Section 53.61 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... component parts for firearms are includible in the price for which the article is sold. (3) Nontaxable parts...

  14. 26 CFR 1.61-21 - Taxation of fringe benefits.

    Science.gov (United States)

    2010-04-01

    ... country club or other social club, and an employer-provided ticket to an entertainment or sporting event...) Effective date. (7) Outline of this section. § 1.61-21 (b) Valuation of fringe benefits (1) In general. (2...-provided aircraft for which the employer does not furnish a pilot. § 1.61-21 (c) Special valuation rules...

  15. 27 CFR 479.61 - Rate of tax.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Rate of tax. 479.61... OTHER FIREARMS Tax on Making Firearms § 479.61 Rate of tax. Except as provided in this subpart, there shall be levied, collected, and paid upon the making of a firearm a tax at the rate of $200 for each...

  16. 40 CFR 61.03 - Units and abbreviations.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Units and abbreviations. 61.03 Section...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.03 Units and abbreviations. Used in this part are abbreviations and symbols of units of measure. These are defined as follows: (a...

  17. 40 CFR 61.145 - Standard for demolition and renovation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standard for demolition and renovation. 61.145 Section 61.145 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... facility components at the beginning, middle, and end of each workday and keep daily temperature records...

  18. 36 CFR 910.61 - Height of development.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Height of development. 910.61 Section 910.61 Parks, Forests, and Public Property PENNSYLVANIA AVENUE DEVELOPMENT CORPORATION GENERAL GUIDELINES AND UNIFORM STANDARDS FOR URBAN PLANNING AND DESIGN OF DEVELOPMENT WITHIN THE PENNSYLVANIA AVENUE...

  19. 34 CFR 200.61 - Parents' right to know.

    Science.gov (United States)

    2010-07-01

    ..., and the field of discipline of the certification or degree. (4) Whether the child is provided services... parent's child has been assigned, or has been taught for four or more consecutive weeks by, a teacher of... 34 Education 1 2010-07-01 2010-07-01 false Parents' right to know. 200.61 Section 200.61 Education...

  20. 28 CFR 33.61 - Review of State applications.

    Science.gov (United States)

    2010-07-01

    ... Criminal Justice Block Grants Submission and Review of Applications § 33.61 Review of State applications. (a) Review criteria. The Act provides the basis for review and approval or disapproval of state... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Review of State applications. 33.61...

  1. 40 CFR 61.144 - Standard for manufacturing.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standard for manufacturing. 61.144... § 61.144 Standard for manufacturing. (a) Applicability. This section applies to the following manufacturing operations using commercial asbestos. (1) The manufacture of cloth, cord, wicks, tubing, tape...

  2. 38 CFR 61.10 - Capital grants-general.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Capital grants-general. 61.10 Section 61.10 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED... capital grants to public or nonprofit private entities so they can assist homeless veterans by helping to...

  3. 38 CFR 61.20 - Life Safety Code capital grants.

    Science.gov (United States)

    2010-07-01

    ... grants. 61.20 Section 61.20 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... grant under section 3 of the Homeless Veterans Comprehensive Service Programs Act of 1992 (Public Law... the level of care for which VA awarded the applicant a grant under the Homeless Veterans Comprehensive...

  4. 38 CFR 61.11 - Applications for capital grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Applications for capital grants. 61.11 Section 61.11 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS... grant under this part that: (i) The project will be used principally to furnish to veterans the level of...

  5. 10 CFR 431.61 - Purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... subpart contains energy conservation requirements for commercial refrigerators, freezers and refrigerator-freezers, pursuant to Part C of Title III of the Energy Policy and Conservation Act, as amended, 42 U.S.C... 10 Energy 3 2010-01-01 2010-01-01 false Purpose and scope. 431.61 Section 431.61 Energy DEPARTMENT...

  6. 31 CFR 360.61 - Payment after death.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment after death. 360.61 Section 360.61 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... after death. After the death of the ward, and at any time prior to the representative's discharge, the...

  7. 31 CFR 353.61 - Payment after death.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Payment after death. 353.61 Section 353.61 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... Payment after death. After the death of the ward, and at any time prior to the representative's discharge...

  8. 20 CFR 226.61 - Use of military service.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Use of military service. 226.61 Section 226... § 226.61 Use of military service. (a) Claim for use of military service. An employee is deemed to have filed a claim for the use of military service and earnings as service and compensation under the...

  9. 14 CFR 1260.61 - Allocation of risk/liability.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Allocation of risk/liability. 1260.61... AGREEMENTS General Special Conditions § 1260.61 Allocation of risk/liability. Allocation of Risk/Liability... make any claim against NASA or the U.S. Government with respect to the injury or death of its employees...

  10. 40 CFR 61.09 - Notification of startup.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Notification of startup. 61.09 Section...) NATIONAL EMISSION STANDARDS FOR HAZARDOUS AIR POLLUTANTS General Provisions § 61.09 Notification of startup. (a) The owner or operator of each stationary source which has an initial startup after the effective...

  11. 14 CFR 34.61 - Turbine fuel specifications.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Turbine fuel specifications. 34.61 Section... FUEL VENTING AND EXHAUST EMISSION REQUIREMENTS FOR TURBINE ENGINE POWERED AIRPLANES Test Procedures for Engine Exhaust Gaseous Emissions (Aircraft and Aircraft Gas Turbine Engines) § 34.61 Turbine fuel...

  12. 49 CFR 220.61 - Radio transmission of mandatory directives.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Radio transmission of mandatory directives. 220.61... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD COMMUNICATIONS Radio and Wireless Communication Procedures § 220.61 Radio transmission of mandatory directives. (a) Each mandatory directive may be transmitted by...

  13. 47 CFR 43.61 - Reports of international telecommunications traffic.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Reports of international telecommunications traffic. 43.61 Section 43.61 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON... Reports of international telecommunications traffic. (a) Each common carrier engaged in providing...

  14. 14 CFR 61.87 - Solo requirements for student pilots.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Solo requirements for student pilots. 61.87... (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Student Pilots § 61.87 Solo requirements for student pilots. (a) General. A student pilot may not operate an aircraft in solo...

  15. Striatal enriched phosphatase 61 dephosphorylates Fyn at phosphotyrosine 420.

    Science.gov (United States)

    Nguyen, Tri-Hung; Liu, Jian; Lombroso, Paul J

    2002-07-05

    A family of protein tyrosine phosphatases enriched within the central nervous system called striatal enriched phosphatase (STEP) has been implicated in the regulation of the N-methyl-d-aspartate receptor. STEP(61), a membrane-associated isoform located in the postsynaptic densities (PSDs) of striatal neurons, contains two transmembrane domains, two proline-rich domains, and a kinase-interacting motif. This study demonstrates that STEP(61) associates with Fyn, a member of the Src family kinases that is also enriched in PSDs. By using human embryonic kidney 293 cells for co-transfection, we determined that a substrate-trapping variant (STEP(61) CS) binds to Fyn but not to other members of the Src family present in PSDs. In a complementary experiment, myc-tagged Fyn immunoprecipitates STEP(61) CS. STEP(61) binds to Fyn through one of its proline-rich domains and the kinase-interacting motif domain, whereas Fyn binds to STEP(61) through its Src homology 2 domain and the unique N-terminal domain. STEP(61) CS pulls down Fyn when the Tyr(420) site is phosphorylated. In vitro, wild-type STEP(61) dephosphorylates Fyn at Tyr(420) but not at Tyr(531). These results suggest that STEP regulates the activity of Fyn by specifically dephosphorylating the regulatory Tyr(420) and may be one mechanism by which Fyn activity is decreased within PSDs.

  16. 27 CFR 1.61 - Use of wine.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Use of wine. 1.61 Section..., NONINDUSTRIAL USE OF DISTILLED SPIRITS AND WINE, BULK SALES AND BOTTLING OF DISTILLED SPIRITS Nonindustrial Use of Distilled Spirits and Wine Uses Regarded As Industrial § 1.61 Use of wine. The following uses of...

  17. 14 CFR 61.189 - Flight instructor records.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight instructor records. 61.189 Section...) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors Other than Flight Instructors With a Sport Pilot Rating § 61.189 Flight instructor records. (a) A flight instructor...

  18. 14 CFR 63.61 - Flight navigator courses.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight navigator courses. 63.61 Section 63...) AIRMEN CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.61 Flight navigator courses. An applicant for approval of a flight navigator course must submit a letter to the Administrator...

  19. 14 CFR 61.193 - Flight instructor privileges.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Flight instructor privileges. 61.193... (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors Other than Flight Instructors With a Sport Pilot Rating § 61.193 Flight instructor privileges. A person who...

  20. 7 CFR 51.61 - Congressional interest in contracts.

    Science.gov (United States)

    2010-01-01

    ....61 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 FRESH FRUITS, VEGETABLES AND OTHER PRODUCTS 1,2 (INSPECTION, CERTIFICATION, AND...

  1. Phenotype abnormality: 61 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 61 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u1ria224u567i abnormal for trait of morphology... in organ named obsolete microgametophyte ... obsolete microgametophyte ... abnormal ... morphology

  2. Analysis list: NKX6-1 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NKX6-1 Digestive tract + hg19 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/NK...X6-1.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/NKX6-1.5.tsv http://dbarchive.bioscien...cedbc.jp/kyushu-u/hg19/target/NKX6-1.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/NKX6-1.Dige

  3. 14 CFR 298.61 - Reporting of traffic statistics.

    Science.gov (United States)

    2010-01-01

    ... Requirements § 298.61 Reporting of traffic statistics. (a) Each commuter air carrier and small certificated air... industry designators. An industry source of these industry designator codes is the Official Airline Guide... specifications for filing data on diskette media apply. (ii) Reporting medium. Microcomputer ADP data submission...

  4. 14 CFR 61.123 - Eligibility requirements: General.

    Science.gov (United States)

    2010-01-01

    ... (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Commercial Pilots § 61.123 Eligibility requirements: General. To be eligible for a commercial pilot certificate, a person... Administrator may place such operating limitations on that applicant's pilot certificate as are necessary for...

  5. 14 CFR 61.133 - Commercial pilot privileges and limitations.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Commercial pilot privileges and limitations... TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Commercial Pilots § 61.133 Commercial pilot privileges and limitations. (a) Privileges—(1) General. A person who...

  6. 38 CFR 61.33 - Payment of per diem.

    Science.gov (United States)

    2010-07-01

    ...) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.33 Payment of per diem. (a) A capital grant... non-grant recipient for those homeless veterans— (1) Who VA referred to the grant recipient or non... per diem recipient for furnishing services to homeless veterans that the per diem recipient certifies...

  7. 14 CFR 61.39 - Prerequisites for practical tests.

    Science.gov (United States)

    2010-01-01

    ... practical test and has completed the pilot in command aircraft qualification training program that is... (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.39... test and has satisfactorily accomplished that operator's approved— (i) Pilot in command aircraft...

  8. LANL Contributions to the B61 LIfe Extension Program

    Energy Technology Data Exchange (ETDEWEB)

    Corpion, Juan Carlos [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-02-10

    The Los Alamos National Laboratory (LANL) has a long, proud heritage in science and innovation that extends 70 years. Although the Laboratory’s primary responsibility is assuring the safety and reliability of the nation’s nuclear deterrent, Laboratory staff work on a broad range of advanced technologies to provide the best, most effective scientific and engineering solutions to the nation’s critical security challenges. The world is rapidly changing, but this essential responsibility remains the LANL’s core mission. LANL is the Design Laboratory for the nuclear explosive package of the B61 Air Force bomb. The B61-12 Life Extension Program (LEP) activities at LANL will increase the lifetime of the bomb and provide safety and security options to meet security environments both today and in the future. The B61’s multiple-platform functionality, unique safety features, and large number of components make the B61-12 LEP one of the most complex LEPs ever attempted. Over 230 LANL scientists, engineers, technicians, and support personnel from across the Laboratory are bringing decades of interdisciplinary knowledge, technical expertise, and leading-edge capabilities to LANL’s work on the LEP.

  9. Cross reaction between P-61 sunflower seedlings oleosomal protein ...

    African Journals Online (AJOL)

    A true triacylglycerol lipase was detected in germinating sunflower (Helianthus annuus L.) seedlings associated to oleosomes. This enzyme that has not yet been identified was partially purified as shown by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS PAGE) (10%); two protein bands, P-61 and P-66 ...

  10. 22 CFR 61.5 - Authentication procedures-Imports.

    Science.gov (United States)

    2010-04-01

    ... AUDIO-VISUAL MATERIALS § 61.5 Authentication procedures—Imports. (a) Applicants seeking Department authentication of foreign produced audio-visual materials shall submit to the Department a bona fide foreign certificate, a copy or example of the material for which authentication is sought, and related collateral...

  11. 22 CFR 61.4 - Certification procedures-Exports.

    Science.gov (United States)

    2010-04-01

    ... AUDIO-VISUAL MATERIALS § 61.4 Certification procedures—Exports. (a) Applicants seeking certification of U.S. produced audio-visual materials shall submit to the Department a completed Application Form for each subject or series for which certification is sought. Collateral instructional material, if any...

  12. 22 CFR 61.7 - Review and appeal procedures.

    Science.gov (United States)

    2010-04-01

    ... Foreign Relations DEPARTMENT OF STATE PUBLIC DIPLOMACY AND EXCHANGES WORLD-WIDE FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.7 Review and appeal procedures. (a) An applicant may request a formal review of any adverse... and any data upon which such argument is based. A copy of the material for which certification or...

  13. 22 CFR 61.3 - Certification and authentication criteria.

    Science.gov (United States)

    2010-04-01

    ... AUDIO-VISUAL MATERIALS § 61.3 Certification and authentication criteria. (a) The Department shall certify or authenticate audio-visual materials submitted for review as educational, scientific and... of the material. (b) The Department will not certify or authenticate any audio-visual material...

  14. 22 CFR 61.6 - Consultation with subject matter specialists.

    Science.gov (United States)

    2010-04-01

    ... FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.6 Consultation with subject matter specialists. (a) The... assisting the Department in its determination of whether materials for which export certification or import... determine eligibility of material for certification or authentication based in part on the opinions obtained...

  15. 17 CFR 200.61 - Impressions of influence.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Impressions of influence. 200...; CONDUCT AND ETHICS; AND INFORMATION AND REQUESTS Canons of Ethics § 200.61 Impressions of influence. A... influence him, that any person unduly enjoys his favor or that he is affected in any way by the rank...

  16. 38 CFR 61.82 - Resident rent for supportive housing.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Resident rent for... AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.82 Resident rent for supportive housing. (a) Each resident of supportive housing may be required to pay rent in an amount determined by...

  17. 19 CFR 4.61 - Requirements for clearance.

    Science.gov (United States)

    2010-04-01

    ... TREASURY VESSELS IN FOREIGN AND DOMESTIC TRADES Foreign Clearances § 4.61 Requirements for clearance. (a... either on the Customs Form 1300 or by approved electronic means. Customs port directors may permit the... (see § 4.71). (16) Inspection of meat, meat-food products, and inedible fats (see § 4.72). (17...

  18. 14 CFR 61.159 - Aeronautical experience: Airplane category rating.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aeronautical experience: Airplane category... Transport Pilots § 61.159 Aeronautical experience: Airplane category rating. (a) Except as provided in... certificate with an airplane category and class rating must have at least 1,500 hours of total time as a pilot...

  19. 46 CFR 61.35-3 - Required tests and checks.

    Science.gov (United States)

    2010-10-01

    ... activated. (10) Feed water flow controls. The feed water flow limit device (found on steam boilers and water... INSPECTIONS Design Verification and Periodic Testing for Automatic Auxiliary Boilers § 61.35-3 Required tests... level controls must be tested by slowly lowering the water level in the boiler. Each operating water...

  20. Beethoven, Ludwig van: Violinkonzert D-Dur op. 61

    Index Scriptorium Estoniae

    1997-01-01

    Uuest heliplaadist "Beethoven, Ludwig van: Violinkonzert D-Dur op. 61 (Kadenz: Alfred Schnittke). Romanzen für Violine und Orchester op. 40 und 50. Estonian National Symphony Orchestra, Arvo Volmer". Globe GLO 5155, distribution Talis (CD:153F). 1996. TT:1h 01'56"

  1. 19 CFR 146.61 - Constructive transfer to Customs territory.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Constructive transfer to Customs territory. 146.61... Constructive transfer to Customs territory. The port director shall accept receipt of any entry in proper form... constructively transferred to Customs territory at that time, even though the merchandise remains physically in...

  2. 47 CFR 61.74 - References to other instruments.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false References to other instruments. 61.74 Section... References to other instruments. (a) Except as otherwise provided in this and other sections of this part, no... other document or instrument. (b) Tariffs for end-on-end through services may reference the tariffs of...

  3. 36 CFR 1192.61 - Public information system.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Public information system... Rapid Rail Vehicles and Systems § 1192.61 Public information system. (a)(1) Requirements. Each vehicle... line identification information. (2) Exception. Where station announcement systems provide information...

  4. 12 CFR 792.61 - Accounting for disclosures.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Accounting for disclosures. 792.61 Section 792... Accounting for disclosures. (a) Each system manager identified in the “Notice of Systems of Records” must establish a system of accounting for all disclosures of information or records under the Privacy Act made...

  5. 14 CFR 61.195 - Flight instructor limitations and qualifications.

    Science.gov (United States)

    2010-01-01

    ... Instructors Other than Flight Instructors With a Sport Pilot Rating § 61.195 Flight instructor limitations and... instructor certificate with the applicable category and class rating; and (2) If appropriate, a type rating... instrument rating, a type rating not limited to VFR, or the instrument training required for commercial pilot...

  6. NA61/SHINE low energy program at SPS

    CERN Document Server

    Abgrall, N.; Andrieu, B.; Anticic, T.; Antoniou, N.; Argyriades, J.; Asryan, A.G.; Baatar, B.; Blondel, A.; Blumer, J.; Boldizsar, L.; Bravar, A.; Brzychczyk, J.; Bubak, A.; Bunyatov, S.A.; Choi, K.-U.; Christakoglou, P.; Chung, P.; Cleymans, J.; Derkach, D.A.; Diakonos, F.; Dominik, W.; Dumarchez, J.; Engel, R.; Ereditato, A.; Feofilov, G.A.; Fodor, Z.; Ferrero, A.; Gazdzicki, M.; Golubeva, M.; Grebieszkow, K.; Grzeszczuk, A.; Guber, F.; Hasegawa, T.; Haungs, A.; Igolkin, S.; Ivanov, A.S.; Ivashkin, A.; Kadija, K.; Katrynska, N.; Kielczewska, D.; Kikola, D.; Kisiel, J.; Kobayashi, T.; Kolesnikov, V.I.; Kolev, D.; Kolevatov, R.S.; Kondratiev, V.P.; Kowalski, S.; Kurepin, A.; Lacey, R.; Laszlo, A.; Lyubushkin, V.V.; Majka, Z.; Malakhov, A.I.; Marchionni, A.; Marcinek, A.; Maris, I.; Matveev, V.; Melkumov, G.L.; Meregaglia, A.; Messina, M.; Mijakowski, P.; Mitrovski, M.; Montaruli, T.; Mrowczynski, St.; Murphy, S.; Nakadaira, T.; Naumenko, P.A.; Nikolic, V.; Nishikawa, K.; Palczewski, T.; Palla, G.; Panagiotou, A.D.; Peryt, W.; Planeta, R.; Pluta, J.; Popov, B.A.; Posiadala, M.; Przewlocki, P.; Rauch, W.; Ravonel, M.; Renfordt, R.; Rohrich, D.; Rondio, E.; Rossi, B.; Roth, M.; Rubbia, A.; Rybczynski, M.; Sadovsky, A.; Sakashita, K.; Schuster, T.; Sekiguchi, T.; Seyboth, P.; Shibata, M.; Sissakian, A.N.; Skrzypczak, E.; Slodkowski, M.; Sorin, A.S.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Strabel, C.; Stroebele, H.; Susa, T.; Szentpetery, I.; Szuba, M.; Tada, M.; Taranenko, A.; Tsenov, R.; Ulrich, R.; Unger, M.; Vassiliou, M.; Vechernin, V.V.; Vesztergombi, G.; Wlodarczyk, Z.; Wojtaszek, A.; Zipper, W.

    2009-01-01

    Status of the new experimental program to study hadron production in hadron-nucleus and nucleus-nucleus collisions at the CERN SPS will be presented. A physics motivation will be given for the part of the program related to the physics of strongly interacting matter. Upgrades of the NA61 experimental set-up and data taking plans will be described in detail.

  7. 14 CFR 61.83 - Eligibility requirements for student pilots.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Eligibility requirements for student pilots... TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS Student Pilots § 61.83 Eligibility requirements for student pilots. To be eligible for a student pilot...

  8. NA61/SHINE Data For Long Baseline Neutrino Experiments

    CERN Document Server

    Hälser, Alexis

    2015-01-01

    Accelerator based long baseline neutrino experiments require precise neutrino fl ux predictions to reach their physics goals. These experiments are commonly based on a set of two detectors. At the near detector, cross section measurements are performed and the neutrino fl ux can be observed before oscillation, while at the far detector the signal for neutrino oscillations is studied. An accurate knowledge on hadron production is mandatory in order to predict the neutrino fluxes. The NA61/SHINE facility at the CERN SPS has proven its ability to deliver high quality measurements of hadron production for the long baseline neutrino experiments. In this paper, the latest results from N A61 /SHINE for the neutrino physics programme are reviewed and future plans are presented.

  9. Mission control activity during STS-61 EVA-1

    Science.gov (United States)

    1993-01-01

    Flight controllers Harry Black (left foreground) and Kevin McCluney (right foreground) monitor the televised activity of two space walkers during the first STS-61 extravehicular activity (EVA). Astronauts F. Story Musgrave and Jeffrey A. Hoffman were performing a variety of equipment replacements. At the Integrated Communications Officer Console (INCO) Black plays a role in controlling the TV while McLuney's duties deal with maintenance, mechanical, arm and crew systems.

  10. Mission control activity during STS-61 EVA-2

    Science.gov (United States)

    1993-01-01

    Harry Black, at the Integrated Communications Officer's console in the Mission Control Center (MCC), monitors the second extravehicular activity (EVA-2) of the STS-61 Hubble Space Telescope (HST) servicing mission. Others pictured, left to right, are Judy Alexander, Kathy Morrison and Linda Thomas. Note monitor scene of one of HST's original solar array panels floating in space moments after being tossed away by Astronaut Kathryn C. Thornton.

  11. 40 CFR 61.245 - Test methods and procedures.

    Science.gov (United States)

    2010-07-01

    ...)) (English units) Ci = Concentration of sample component “i” in ppm, as measured by Method 18 of appendix A... specified in § 61.18). Hi = net heat of combustion of sample component “i” at 25 °C and 760 mm Hg (77 °F and... units) = 28.56 ft/sec (English units) K2 = 0.7084 m4/(MJ-sec) (metric units) = 0.087 ft4/(Btu-sec...

  12. Isotopic ratios in outbursting comet C/2015 ER61

    Science.gov (United States)

    Yang, Bin; Hutsemékers, Damien; Shinnaka, Yoshiharu; Opitom, Cyrielle; Manfroid, Jean; Jehin, Emmanuël; Meech, Karen J.; Hainaut, Olivier R.; Keane, Jacqueline V.; Gillon, Michaël

    2018-02-01

    Isotopic ratios in comets are critical to understanding the origin of cometary material and the physical and chemical conditions in the early solar nebula. Comet C/2015 ER61 (PANSTARRS) underwent an outburst with a total brightness increase of 2 magnitudes on the night of 2017 April 4. The sharp increase in brightness offered a rare opportunity to measure the isotopic ratios of the light elements in the coma of this comet. We obtained two high-resolution spectra of C/2015 ER61 with UVES/VLT on the nights of 2017 April 13 and 17. At the time of our observations, the comet was fading gradually following the outburst. We measured the nitrogen and carbon isotopic ratios from the CN violet (0, 0) band and found that 12C/13C = 100 ± 15, 14N/15N = 130 ± 15. In addition, we determined the 14N/15N ratio from four pairs of NH2 isotopolog lines and measured 14N/15N = 140 ± 28. The measured isotopic ratios of C/2015 ER61 do not deviate significantly from those of other comets.

  13. 40 CFR 61.149 - Standard for waste disposal for asbestos mills.

    Science.gov (United States)

    2010-07-01

    ... asbestos mills. 61.149 Section 61.149 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Standard for Asbestos § 61.149 Standard for waste disposal for asbestos mills. Each owner or operator of any source covered under the provisions of § 61.142 shall: (a) Deposit all asbestos-containing waste...

  14. A Novel Tool for Peptide Pattern Recognition Identifies 13 Subgroups of the GH61 Family

    DEFF Research Database (Denmark)

    Busk, Peter Kamp; Lange, Mette; Lange, Lene

    2011-01-01

    Proteins of the glycosyl hydrolase family 61 (gh61) are important proteins for fungal degradation of biomass. There are 132 entries for gh61 in the CAZY database, no subfamilies have been defined and each fungus may have several gh61s with very different sequences. Alignment of highly divergent s...

  15. Recent results from NA61/SHINE at the CERN SPS

    Directory of Open Access Journals (Sweden)

    Palczewski Tomasz Jan

    2014-01-01

    Full Text Available This contribution is devoted to looking at the NA61/SHINE experiment [1] through the prism of the needs of neutrino oscillation experiments. The new preliminary results on hadron production measurements from p+C (thin target - 0.04 λI interactions at 31 GeV/c from 2009 data are presented. These results are crucial for the precise determination of background contamination in the neutrino flux of the Tokai to Kamioka (T2K experiment at J-PARC [2].

  16. Pyogenic spinal osteomyelitis: a review of 61 cases.

    Science.gov (United States)

    Silverthorn, K G; Gillespie, W J

    1986-02-12

    The presentation and outcome of 61 cases of nontuberculous spinal osteomyelitis were reviewed. Although the commonest presentation was subacute, with back pain predominating, 10% had septicaemia and 7% paraperesis or paraplegia. Most infections were caudal to the fourth thoracic vertebra. One third were associated with preceding urinary, respiratory, dental or abdominal sepsis. Staphylococcus aureus was the infecting organism in 85% of isolates. Delay in diagnosis was frequent. There were four deaths, and seven individuals remained severely disabled: outcome was otherwise satisfactory. An algorithm for the investigation and management of this uncommon but serious condition is proposed.

  17. [A 61-year-old man with sciatica].

    Science.gov (United States)

    Breivik, Kristin Lif; Laurini, Ricardo; Steen, Rolf; Alstadhaug, Karl Bjørnar

    2009-05-14

    A 61-year-old man was admitted to our department with radicular back-pain and progressive gait-difficulties. On examination he had flaccid paraparesis and bladder-retention. He subsequently developed palsy of n. oculomotorius, dysarthria, right-sided Bells palsy and weakness of his right arm over a 4-week period. He became disoriented and died without a diagnosis. MRI of the brain and columna were negative. Extensive search for malignancies yielded negative results. Cytology specimens were inconclusive and repeated liquor-examinations showed very low glucose levels, mild pleocytosis, elevated protein. Autopsy revealed a small adenocarcinoma of the lung and meningeal carcinomatosis originating from the adenocarcinoma.

  18. Revisiting LS I +61°303 with VLBI astrometry

    Science.gov (United States)

    Wu, Y. W.; Torricelli-Ciamponi, G.; Massi, M.; Reid, M. J.; Zhang, B.; Shao, L.; Zheng, X. W.

    2018-03-01

    We conducted multi-epoch Very Long Baseline Array (VLBA) phase-referenced observations of LS I +61°303 in order to study its precessing radio jet. Compared to similar observations in 2006, we find that the observed elliptical trajectory of emission at 8.4 GHz repeats after the 9 yr gap. The accurate alignment of the emission patterns yields a precession period of 26.926 ± 0.005 d, which is consistent with that determined by Lomb-Scargle analysis of the radio light curve. We analytically model the projection on the sky plane of the peak position of a precessing, synchrotron-emitting jet, which traces an elliptical trajectory on the sky. Comparing the simulation with the VLBA astrometry we improve our knowledge of the geometry of the system. We measure the LS I +61°303 absolute proper motion to be -0.150 ± 0.006 mas yr-1 eastward and -0.264 ± 0.006 mas yr-1 northward. Removing Galactic rotation, this reveals a small, <20 km s-1, non-circular motion, which indicates a very low kick velocity when the black hole was formed.

  19. 14 CFR 61.315 - What are the privileges and limits of my sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... sport pilot certificate? 61.315 Section 61.315 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... INSTRUCTORS Sport Pilots § 61.315 What are the privileges and limits of my sport pilot certificate? (a) If you hold a sport pilot certificate you may act as pilot in command of a light-sport aircraft, except as...

  20. 14 CFR 61.73 - Military pilots or former military pilots: Special rules.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Military pilots or former military pilots: Special rules. 61.73 Section 61.73 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF... Ratings and Pilot Authorizations § 61.73 Military pilots or former military pilots: Special rules. (a...

  1. 42 CFR 61.9 - Payments: Stipends; dependency allowances; travel allowances.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Payments: Stipends; dependency allowances; travel allowances. 61.9 Section 61.9 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES FELLOWSHIPS, INTERNSHIPS, TRAINING FELLOWSHIPS Regular Fellowships § 61.9 Payments: Stipends; dependency...

  2. 22 CFR 40.61 - Aliens present without admission or parole.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Aliens present without admission or parole. 40.61 Section 40.61 Foreign Relations DEPARTMENT OF STATE VISAS REGULATIONS PERTAINING TO BOTH... Immigration Violators § 40.61 Aliens present without admission or parole. INA 212(a)(6)(A)(i) does not apply...

  3. 40 CFR 125.61 - Existence of and compliance with applicable water quality standards.

    Science.gov (United States)

    2010-07-01

    ... applicable water quality standards. 125.61 Section 125.61 Protection of Environment ENVIRONMENTAL PROTECTION... Water Act § 125.61 Existence of and compliance with applicable water quality standards. (a) There must exist a water quality standard or standards applicable to the pollutant(s) for which a section 301(h...

  4. 39 CFR 3004.61 - Freedom of Information Act Public Liaison.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Freedom of Information Act Public Liaison. 3004.61 Section 3004.61 Postal Service POSTAL REGULATORY COMMISSION PERSONNEL PUBLIC RECORDS AND FREEDOM OF INFORMATION ACT § 3004.61 Freedom of Information Act Public Liaison. The Commission designates the Director of...

  5. 46 CFR 61.15-10 - Liquefied-petroleum-gas piping for heating and cooking.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Liquefied-petroleum-gas piping for heating and cooking. 61.15-10 Section 61.15-10 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING PERIODIC TESTS AND INSPECTIONS Periodic Tests of Piping Systems § 61.15-10 Liquefied-petroleum-gas...

  6. 46 CFR 61.30-20 - Automatic control and safety tests.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Automatic control and safety tests. 61.30-20 Section 61... TESTS AND INSPECTIONS Tests and Inspections of Fired Thermal Fluid Heaters § 61.30-20 Automatic control and safety tests. Operational tests and checks of all safety and limit controls, combustion controls...

  7. 9 CFR 3.61 - Primary enclosures used to transport live rabbits.

    Science.gov (United States)

    2010-01-01

    ... live rabbits. 3.61 Section 3.61 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE... and Transportation of Rabbits Transportation Standards § 3.61 Primary enclosures used to transport live rabbits. No person subject to the Animal Welfare regulations shall offer for transportation or...

  8. 38 CFR 61.15 - Obtaining additional information and awarding capital grants.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Obtaining additional information and awarding capital grants. 61.15 Section 61.15 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.15 Obtaining...

  9. 45 CFR 61.13 - Fees applicable to requests for information.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Fees applicable to requests for information. 61.13 Section 61.13 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE... PRACTITIONERS Disclosure of Information by the Healthcare Integrity and Protection Data Bank § 61.13 Fees...

  10. Molecular and clinical study of 61 Angelman syndrome patients

    Energy Technology Data Exchange (ETDEWEB)

    Saitoh, Shinji; Harada, Naoki; Jinno, Yoshihiro; Niikawa, Norio [Nagasaki Univ. School of Medicine (Japan); Imaizumi, Kiyoshi; Kuroki, Yoshikazu; Fukushima; Yoshimitsu; Sugimoto, Tateo; Renedo, Monica

    1994-08-15

    We analyzed 61 Angelman syndrome (AS) patients by cytogenetic and molecular techniques. On the basis of molecular findings, the patients were classified into the following 4 groups: familial cases without deletion, familial cases with submicroscopic deletion, sporadic cases with deletion, and sporadic cases without deletion. Among 53 sporadic cases, 37 (70%) had molecular deletion, which commonly extended from D15S9 to D15S12, although not all deletions were identical. Of 8 familial cases, 3 sibs from one family had a molecular deletion involving only 2 loci, D15S10 and GABRB3, which define the critical region for AS phenotypes. The parental origin of deletion, both in sporadic and familial cases, was exclusively maternal and consistent with a genomic imprinting hypothesis. Among sporadic and familial cases without deletion, no uniparental disomy was found and most of them were shown to inherit chromosomes 15 from both parents (biparental inheritance). A discrepancy between cytogenetic and molecular deletion was observed in 14 (26%) of 53 patients in whom cytogenetic analysis could be performed. Ten (43%) of 23 patients with a normal karyotype showed a molecular deletion, and 4 (13%) of 30 patients with cytogenetic deletion, del(15) (q11q13), showed no molecular deletion. Most clinical manifestations, including neurological signs and facial characteristics, were not distinct in each group except for hypopigmentation of skin or hair. Familial cases with submicroscopic deletion were not associated with hypopigmentation. These findings suggested that a gene for hypopigmentation is located outside the critical region of AS and is not imprinted. 37 refs., 2 figs., 4 tabs.

  11. Sec61β, a subunit of the Sec61 protein translocation channel at the Endoplasmic Reticulum, is involved in the transport of Gurken to the plasma membrane.

    Directory of Open Access Journals (Sweden)

    Kelkar Anshuman

    2009-02-01

    Full Text Available Abstract Background Protein translocation across the membrane of the Endoplasmic Reticulum (ER is the first step in the biogenesis of secretory and membrane proteins. Proteins enter the ER by the Sec61 translocon, a proteinaceous channel composed of three subunits, α, β and γ. While it is known that Sec61α forms the actual channel, the function of the other two subunits remains to be characterized. Results In the present study we have investigated the function of Sec61β in Drosophila melanogaster. We describe its role in the plasma membrane traffic of Gurken, the ligand for the Epidermal Growth Factor (EGF receptor in the oocyte. Germline clones of the mutant allele of Sec61β show normal translocation of Gurken into the ER and transport to the Golgi complex, but further traffic to the plasma membrane is impeded. The defect in plasma membrane traffic due to absence of Sec61β is specific for Gurken and is not due to a general trafficking defect. Conclusion Based on our study we conclude that Sec61β, which is part of the ER protein translocation channel affects a post-ER step during Gurken trafficking to the plasma membrane. We propose an additional role of Sec61β beyond protein translocation into the ER.

  12. Oxidoreductive Cellulose Depolymerization by the Enzymes Cellobiose Dehydrogenase and Glycoside Hydrolase 61▿†

    Science.gov (United States)

    Langston, James A.; Shaghasi, Tarana; Abbate, Eric; Xu, Feng; Vlasenko, Elena; Sweeney, Matt D.

    2011-01-01

    Several members of the glycoside hydrolase 61 (GH61) family of proteins have recently been shown to dramatically increase the breakdown of lignocellulosic biomass by microbial hydrolytic cellulases. However, purified GH61 proteins have neither demonstrable direct hydrolase activity on various polysaccharide or lignacious components of biomass nor an apparent hydrolase active site. Cellobiose dehydrogenase (CDH) is a secreted flavocytochrome produced by many cellulose-degrading fungi with no well-understood biological function. Here we demonstrate that the binary combination of Thermoascus aurantiacus GH61A (TaGH61A) and Humicola insolens CDH (HiCDH) cleaves cellulose into soluble, oxidized oligosaccharides. TaGH61A-HiCDH activity on cellulose is shown to be nonredundant with the activities of canonical endocellulase and exocellulase enzymes in microcrystalline cellulose cleavage, and while the combination of TaGH61A and HiCDH cleaves highly crystalline bacterial cellulose, it does not cleave soluble cellodextrins. GH61 and CDH proteins are coexpressed and secreted by the thermophilic ascomycete Thielavia terrestris in response to environmental cellulose, and the combined activities of T. terrestris GH61 and T. terrestris CDH are shown to synergize with T. terrestris cellulose hydrolases in the breakdown of cellulose. The action of GH61 and CDH on cellulose may constitute an important, but overlooked, biological oxidoreductive system that functions in microbial lignocellulose degradation and has applications in industrial biomass utilization. PMID:21821740

  13. Down-regulation of BDNF in cell and animal models increases striatal-enriched protein tyrosine phosphatase 61 (STEP61 ) levels.

    Science.gov (United States)

    Xu, Jian; Kurup, Pradeep; Azkona, Garikoitz; Baguley, Tyler D; Saavedra, Ana; Nairn, Angus C; Ellman, Jonathan A; Pérez-Navarro, Esther; Lombroso, Paul J

    2016-01-01

    Brain-derived neurotrophic factor (BDNF) regulates synaptic strengthening and memory consolidation, and altered BDNF expression is implicated in a number of neuropsychiatric and neurodegenerative disorders. BDNF potentiates N-methyl-D-aspartate receptor function through activation of Fyn and ERK1/2. STriatal-Enriched protein tyrosine Phosphatase (STEP) is also implicated in many of the same disorders as BDNF but, in contrast to BDNF, STEP opposes the development of synaptic strengthening. STEP-mediated dephosphorylation of the NMDA receptor subunit GluN2B promotes internalization of GluN2B-containing NMDA receptors, while dephosphorylation of the kinases Fyn, Pyk2, and ERK1/2 leads to their inactivation. Thus, STEP and BDNF have opposing functions. In this study, we demonstrate that manipulation of BDNF expression has a reciprocal effect on STEP61 levels. Reduced BDNF signaling leads to elevation of STEP61 both in BDNF(+/-) mice and after acute BDNF knockdown in cortical cultures. Moreover, a newly identified STEP inhibitor reverses the biochemical and motor abnormalities in BDNF(+/-) mice. In contrast, increased BDNF signaling upon treatment with a tropomyosin receptor kinase B agonist results in degradation of STEP61 and a subsequent increase in the tyrosine phosphorylation of STEP substrates in cultured neurons and in mouse frontal cortex. These findings indicate that BDNF-tropomyosin receptor kinase B signaling leads to degradation of STEP61 , while decreased BDNF expression results in increased STEP61 activity. A better understanding of the opposing interaction between STEP and BDNF in normal cognitive functions and in neuropsychiatric disorders will hopefully lead to better therapeutic strategies. Altered expression of BDNF and STEP61 has been implicated in several neurological disorders. BDNF and STEP61 are known to regulate synaptic strengthening, but in opposite directions. Here, we report that reduced BDNF signaling leads to elevation of STEP61 both in

  14. 9 CFR 201.61 - Market agencies selling or purchasing livestock on commission; relationships with dealers.

    Science.gov (United States)

    2010-01-01

    ... INSPECTION, PACKERS AND STOCKYARDS ADMINISTRATION (PACKERS AND STOCKYARDS PROGRAMS), DEPARTMENT OF AGRICULTURE REGULATIONS UNDER THE PACKERS AND STOCKYARDS ACT Trade Practices § 201.61 Market agencies selling...

  15. Criticality Safety Validation of Scale 6.1

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, William BJ J [ORNL; Rearden, Bradley T [ORNL

    2011-11-01

    The computational bias of criticality safety computer codes must be established through the validation of the codes to critical experiments. A large collection of suitable experiments has been vetted by the International Criticality Safety Benchmark Experiment Program (ICSBEP) and made available in the International Handbook of Evaluated Criticality Safety Benchmark Experiments (IHECSBE). A total of more than 350 cases from this reference have been prepared and reviewed within the Verified, Archived Library of Inputs and Data (VALID) maintained by the Reactor and Nuclear Systems Division at Oak Ridge National Laboratory. The performance of the KENO V.a and KENO-VI Monte Carlo codes within the Scale 6.1 code system with ENDF/B-VII.0 cross-section data in 238-group and continuous energy is assessed using the VALID models of benchmark experiments. The TSUNAMI tools for sensitivity and uncertainty analysis are utilized to examine some systems further in an attempt to identify potential causes of unexpected results. The critical experiments available for validation of the KENO V.a code cover eight different broad categories of systems. These systems use a range of fissile materials including a range of uranium enrichments, various plutonium isotopic vectors, and mixed uranium-plutonium oxides. The physical form of the fissile material also varies and is represented as metal, solutions, or arrays of rods or plates in a water moderator. The neutron energy spectra of the systems also vary and cover both fast and thermal spectra. Over 300 of the total cases used utilize the KENO V.a code. The critical experiments available for the validation of the KENO-VI code cover three broad categories of systems. The fissile materials in the systems vary and include high and intermediate-enrichment uranium and mixed uranium/plutonium oxides. The physical form of the fissile material is either metal or rod arrays in water. As with KENO V.a, both fast and thermal neutron energy spectra

  16. 29 CFR 4022.61 - Limitations on benefit payments by plan administrator.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Limitations on benefit payments by plan administrator. 4022.61 Section 4022.61 Labor Regulations Relating to Labor (Continued) PENSION BENEFIT GUARANTY... higher benefit. (e) PBGC authority to modify procedures. In order to avoid abuse of the plan termination...

  17. 45 CFR 61.6 - Reporting errors, omissions, revisions or whether an action is on appeal.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Reporting errors, omissions, revisions or whether an action is on appeal. 61.6 Section 61.6 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON...

  18. 47 CFR 61.47 - Adjustments to the SBI; pricing bands.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Adjustments to the SBI; pricing bands. 61.47... (CONTINUED) TARIFFS General Rules for Dominant Carriers § 61.47 Adjustments to the SBI; pricing bands. (a) In... restructured service) that will remain or become available after restructuring. (e) Pricing bands shall be...

  19. 42 CFR 61.14 - Separate consideration of information concerning moral character or loyalty.

    Science.gov (United States)

    2010-10-01

    ... moral character or loyalty. 61.14 Section 61.14 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... Separate consideration of information concerning moral character or loyalty. No information in the records or possession of the Public Health Service concerning the moral character or loyalty of a fellow will...

  20. 10 CFR 34.61 - Records of the specific license for industrial radiography.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Records of the specific license for industrial radiography. 34.61 Section 34.61 Energy NUCLEAR REGULATORY COMMISSION LICENSES FOR INDUSTRIAL RADIOGRAPHY AND... Records of the specific license for industrial radiography. Each licensee shall maintain a copy of its...

  1. 42 CFR 61.8 - Benefits: Stipends; dependency allowances; travel allowances; vacation.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Benefits: Stipends; dependency allowances; travel allowances; vacation. 61.8 Section 61.8 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN...; dependency allowances; travel allowances; vacation. Individuals awarded regular fellowships shall be entitled...

  2. 14 CFR 61.37 - Knowledge tests: Cheating or other unauthorized conduct.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Knowledge tests: Cheating or other unauthorized conduct. 61.37 Section 61.37 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF....37 Knowledge tests: Cheating or other unauthorized conduct. (a) An applicant for a knowledge test may...

  3. 77 FR 52310 - Expansion of Foreign-Trade Zone 61, San Juan, Puerto Rico

    Science.gov (United States)

    2012-08-29

    ... Foreign-Trade Zones Board Expansion of Foreign-Trade Zone 61, San Juan, Puerto Rico Pursuant to its...-Trade Zones Board (the Board) adopts the following Order: Whereas, the Puerto Rico Trade and Export... FTZ 61 to include a site in Aguadilla, Puerto Rico, adjacent to the San Juan U.S. Customs and Border...

  4. Enhanced lignocellulosic biomass hydrolysis by oxidative lytic polysaccharide monooxygenases (LPMOs) GH61 from Gloeophyllum trabeum.

    Science.gov (United States)

    Jung, Sera; Song, Younho; Kim, Ho Myeong; Bae, Hyeun-Jong

    2015-09-01

    Lignocellulose is a renewable resource that is extremely abundant, and the complete enzymatic hydrolysis of lignocellulose requires a cocktail containing a variety of enzyme groups that act synergistically. The hydrolysis efficiency can be improved by introducing glycoside hydrolase 61 (GH61), a new enzyme that belongs to the auxiliary activity family 9 (AA9). GH61was isolated from Gloeophyllum trabeum and cleaves the glycosidic bonds on the cellulose surface via oxidation of various carbons. In this study, we investigated the properties of GH61. GtGH61 alone did not exhibit any notable activity, but the synergistic activity of GtGH61 with xylanase (GtXyl10G) or cellulase (GtCel5B) showed efficient bioconversion rates of 56 and 174% in pretreated kenaf (Hibiscus cannabinus L.) and oak (Quercus spp.), respectively. Furthermore, the GtGH61 activity was strongly accelerated in the presence of cobalt Co(2+). Enzyme cocktails (GtXyl10G, GtCel5B, and GtGH61) increased the amount of sugar released by 7 and 6% for pretreated oak and kenaf, respectively, and the addition of Co(2+) stimulated bioconversion by 12 and 11% in pretreated oak and kenaf, respectively. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. 14 CFR 61.421 - May I give myself an endorsement?

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false May I give myself an endorsement? 61.421... a Sport Pilot Rating § 61.421 May I give myself an endorsement? No. If you hold a flight instructor certificate with a sport pilot rating, you may not give yourself an endorsement for any certificate, privilege...

  6. Multi-mode to single-mode conversion in a 61 port photonic lantern

    DEFF Research Database (Denmark)

    Noordegraaf, Danny; Skovgaard, Peter M.W.; Maack, Martin D.

    2010-01-01

    Efficient multi-mode (MM) to single-mode (SM) conversion in a 61 port splitter or “Photonic Lantern” is demonstrated. The coupling loss from a 100 µm core diameter MM section to an ensemble of 61 SM fibers and back to another 100 µm core MM section is measured to be as low as 0.76 d...

  7. 41 CFR Appendix A to Part 61 - 300-Federal Contractor Veterans' Employment Report VETS-100A

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 300-Federal Contractor Veterans' Employment Report VETS-100A A Appendix A to Part 61 Public Contracts and Property Management.... A Appendix A to Part 61-300—Federal Contractor Veterans' Employment Report VETS-100A ER19MY08.024...

  8. 41 CFR Appendix A to Part 61 - 250-Federal Contractor Veterans' Employment Report VETS-100

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true 250-Federal Contractor Veterans' Employment Report VETS-100 A Appendix A to Part 61 Public Contracts and Property Management Other... Appendix A to Part 61-250—Federal Contractor Veterans' Employment Report VETS-100 ER05NO08.000 ER05NO08.001...

  9. 7 CFR 15a.61 - Sex as a bona-fide occupational qualification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Sex as a bona-fide occupational qualification. 15a.61... RECEIVING OR BENEFITTING FROM FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs and Activities Prohibited § 15a.61 Sex as a bona-fide occupational...

  10. 7 CFR 1737.61 - Cost allocation for rural and nonrural areas.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Cost allocation for rural and nonrural areas. 1737.61... TELECOMMUNICATIONS LOANS Project Cost Estimation Procedures § 1737.61 Cost allocation for rural and nonrural areas... serve subscribers in nonrural areas, RUS shall allocate costs between rural and nonrural areas. This...

  11. 47 CFR 5.61 - Procedure for obtaining a special temporary authorization.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Procedure for obtaining a special temporary authorization. 5.61 Section 5.61 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EXPERIMENTAL RADIO...) Frequency(ies) desired. (9) Maximum effective radiated power (ERP) or equivalent isotrophically radiated...

  12. 47 CFR 61.193 - Vacation of suspension order; supplements announcing same; etc.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Vacation of suspension order; supplements announcing same; etc. 61.193 Section 61.193 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED...; supplements announcing same; etc. If the Commission vacates a suspension order, the affected carrier must...

  13. Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer.

    Science.gov (United States)

    Chen, Ping-Ping; Li, Wen-Jie; Wang, Yan; Zhao, Song; Li, De-Yun; Feng, Li-Yun; Shi, Xiang-Lin; Koeffler, H Phillip; Tong, Xiang-Jun; Xie, Dong

    2007-06-20

    CCN family, comprising six members (Cyr61, CTGF, Nov, WISP-1, WISP-2, WISP-3), is involved in the stimulation of cell proliferation, migration, adhesion, angiogenesis, and tumorigenesis. Several studies have shown that expression of Cyr61, CTGF, and WISP-1 affects the tumorigenic potential of lung cancer cells in vitro. However, the correlation of expression of CCN family proteins and clinical features of lung cancer remains unknown. In the present work, we quantified the mRNA levels of Cyr61, CTGF, and WISP-1 in samples from 60 primary lung cancers and their matched normal lung tissues by quantitative real-time PCR assay. Downregulation of the Cyr61 and CTGF genes and upregulation of the WISP-1 gene were found in primary lung cancers compared to the paired normal lung tissues. Immunohistochemistry analysis also disclosed a similar expression pattern of Cyr61, CTGF, and WISP-1 protein in paired lung cancer tissues. Statistical analysis revealed significant associations between expression of either Cyr61 or CTGF with tumor stage, tumor histology, metastasis, smoking, and family history at diagnosis. A significant correlation also existed between WISP-1 expression with tumor histology, and patient age. Moreover, expression levels of Cyr61 and CTGF correlated with survival of the lung-cancer patients. Our results suggest that Cyr61, CTGF, and WISP-1 might be implicated in the development and progression of primary lung cancers, and their levels might serve as valuable prognostic markers, as well as potential targets for therapeutic intervention.

  14. 26 CFR 1.381(c)(6)-1 - Depreciation method.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 4 2010-04-01 2010-04-01 false Depreciation method. 1.381(c)(6)-1 Section 1.381... (CONTINUED) INCOME TAXES Insolvency Reorganizations § 1.381(c)(6)-1 Depreciation method. (a) Carryover... corporation which computes its allowance for the depreciation of the property under section 167(b)(2), (3), or...

  15. 27 CFR 27.61 - Containers of distilled spirits to bear closures.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Containers of distilled spirits to bear closures. 27.61 Section 27.61 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO... spirits to bear closures. No person shall transport, buy, possess, or sell, or transfer any imported...

  16. 28 CFR 541.61 - Standard for placement in controlled housing status.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Standard for placement in controlled housing status. 541.61 Section 541.61 Judicial Administration BUREAU OF PRISONS, DEPARTMENT OF JUSTICE INSTITUTIONAL MANAGEMENT INMATE DISCIPLINE AND SPECIAL HOUSING UNITS Procedures for Handling of HIV Positive...

  17. 49 CFR 1242.86 - Industrial development (account XX-61-90).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Industrial development (account XX-61-90). 1242.86 Section 1242.86 Transportation Other Regulations Relating to Transportation (Continued) SURFACE....86 Industrial development (account XX-61-90). These accounts pertain solely to freight service and...

  18. Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    DEFF Research Database (Denmark)

    Wewer Albrechtsen, Nicolai J.; Kuhre, Rune E.; Hornburg, Daniel

    2017-01-01

    that PG 1-61 dose-dependently increases levels of cAMP, through the glucagon receptor, and increases insulin secretion and protein levels of enzymes regulating glycogenolysis and gluconeogenesis. In rats, PG 1-61 increases blood glucose and plasma insulin and decreases plasma levels of amino acids in...

  19. 10 CFR 61.42 - Protection of individuals from inadvertent intrusion.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Protection of individuals from inadvertent intrusion. 61.42 Section 61.42 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR LAND... intrusion. Design, operation, and closure of the land disposal facility must ensure protection of any...

  20. 40 CFR 61.207 - Radium-226 sampling and measurement procedures.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Radium-226 sampling and measurement... for Radon Emissions From Phosphogypsum Stacks § 61.207 Radium-226 sampling and measurement procedures... § 61.206, the owner or operator of a phosphogypsum stack shall measure the average radium-226...

  1. 10 CFR 61.41 - Protection of the general population from releases of radioactivity.

    Science.gov (United States)

    2010-01-01

    ... radioactivity. 61.41 Section 61.41 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSING REQUIREMENTS FOR... from releases of radioactivity. Concentrations of radioactive material which may be released to the... maintain releases of radioactivity in effluents to the general environment as low as is reasonably...

  2. Cyr61 Expression Pattern and Association with Clinicopathological Factors in Patients with Cervical Cancer.

    Science.gov (United States)

    Mayer, Sebastian; Gabriel, Boris; Erbes, Thalia; Timme-Bronsert, Sylvia; Jäger, Markus; Rücker, Gerta; Kuf, Franciska; Bouda, Jiri; Bartakova, Alena; Hausen, Axel Zur; Stickeler, Elmar; Gitsch, Gerald; Hirschfeld, Marc

    2017-05-01

    The pro-angiogenic Cyr61 protein has been associated with tumorigenesis and cancer progression in different gynecological carcinomas. In this study, we evaluated the potential impact and clinical relevance of Cyr61 expression in patients with primary non-metastatic cervical cancer (CC). Cyr61 expression was assessed in tissue specimen of 48 patients with primary CC by immunohistochemical analysis. Expression levels were scored and correlated to clinico-pathological factors and outcome data. High Cyr61 expression levels were present in 54.2% of CC tissues. Associations with histological grade (p=0.030), depth of tumor invasion (p=0.007) and GOG score (p=0.027) were observed. Patients who overexpressed Cyr61 displayed an increased death rate (30.8% vs. 18.2%) and a decreased 5-year-survival (76.9% vs. 86.4%). Our data indicate a potential functional impact of Cyr61 in development and the progression of CC. The definite tumor-relevant function (suppressive/promoting) of Cyr61 in CC and the prognostic relevance of Cyr61 overexpression has to be evaluated in larger cohorts. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  3. 49 CFR 177.841 - Division 6.1 and Division 2.3 materials.

    Science.gov (United States)

    2010-10-01

    ... MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS CARRIAGE BY PUBLIC HIGHWAY Loading and Unloading § 177.841 Division 6.1 and Division 2.3 materials. (See also § 177... 49 Transportation 2 2010-10-01 2010-10-01 false Division 6.1 and Division 2.3 materials. 177.841...

  4. 40 CFR 61.64 - Emission standard for polyvinyl chloride plants.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Emission standard for polyvinyl... Standard for Vinyl Chloride § 61.64 Emission standard for polyvinyl chloride plants. An owner or operator of a polyvinyl chloride plant shall comply with the requirements of this section and § 61.65. (a...

  5. 40 CFR 61.65 - Emission standard for ethylene dichloride, vinyl chloride and polyvinyl chloride plants.

    Science.gov (United States)

    2010-07-01

    ... dichloride, vinyl chloride and polyvinyl chloride plants. 61.65 Section 61.65 Protection of Environment... dichloride, vinyl chloride and polyvinyl chloride plants. An owner or operator of an ethylene dichloride, vinyl chloride, and/or polyvinyl chloride plant shall comply with the requirements of this section. (a...

  6. 45 CFR 61.12 - Requesting information from the Healthcare Integrity and Protection Data Bank.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Requesting information from the Healthcare Integrity and Protection Data Bank. 61.12 Section 61.12 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION...

  7. 45 CFR 61.1 - The Healthcare Integrity and Protection Data Bank.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false The Healthcare Integrity and Protection Data Bank. 61.1 Section 61.1 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS...

  8. 45 CFR 61.14 - Confidentiality of Healthcare Integrity and Protection Data Bank information.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Confidentiality of Healthcare Integrity and Protection Data Bank information. 61.14 Section 61.14 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON...

  9. 50 CFR 260.61 - Sampling plans and procedures for determining lot compliance.

    Science.gov (United States)

    2010-10-01

    ... determining lot compliance. 260.61 Section 260.61 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE... Sampling plans and procedures for determining lot compliance. (a) Except as otherwise provided for in this... shall be selected from each lot in the exact number of sample units indicated for the lot size in the...

  10. 25 CFR 61.4 - Qualifications for enrollment and the deadline for filing application forms.

    Science.gov (United States)

    2010-04-01

    ... deadline for filing application forms will be included in this part 61 by appropriate amendments to this..., amendment to this section will not be required for the procedures contained in this part 61 to govern the... possess at least one-eighth (1/8) degree or more Indian blood; (iii) Who are not enrolled members of...

  11. 14 CFR 61.311 - What flight proficiency requirements must I meet to apply for a sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... meet to apply for a sport pilot certificate? 61.311 Section 61.311 Aeronautics and Space FEDERAL... INSTRUCTORS, AND GROUND INSTRUCTORS Sport Pilots § 61.311 What flight proficiency requirements must I meet to apply for a sport pilot certificate? Except as specified in § 61.329, to apply for a sport pilot...

  12. 14 CFR 61.309 - What aeronautical knowledge must I have to apply for a sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... apply for a sport pilot certificate? 61.309 Section 61.309 Aeronautics and Space FEDERAL AVIATION... GROUND INSTRUCTORS Sport Pilots § 61.309 What aeronautical knowledge must I have to apply for a sport pilot certificate? Except as specified in § 61.329, to apply for a sport pilot certificate you must...

  13. Synaptic NMDA Receptor Activation Induces Ubiquitination and Degradation of STEP61.

    Science.gov (United States)

    Xu, Jian; Kurup, Pradeep; Nairn, Angus C; Lombroso, Paul J

    2017-05-02

    NMDA receptor signaling is critical for the development of synaptic plasticity, learning, and memory, and dysregulation of NMDAR signaling is implicated in a number of neurological disorders including schizophrenia (SZ). Previous work has demonstrated that the STriatal-Enriched protein tyrosine Phosphatase 61 kDa (STEP61) is elevated in human SZ postmortem cortical samples and after administration of psychotomimetics to cultures or mice. Here, we report that activation of synaptic NMDAR by bicuculline or D-serine results in the ubiquitination and proteasomal degradation of STEP61, and increased surface localization of GluN1/GluN2B receptors. Moreover, bicuculline or D-serine treatments rescue the motor and cognitive deficits in MK-801-treated mice and reduce STEP61 in mouse frontal cortex. These results suggest that STEP61 may contribute to the therapeutic effects of D-serine.

  14. Differential regulation of protein tyrosine kinase signalling by Dock and the PTP61F variants.

    Science.gov (United States)

    Willoughby, Lee F; Manent, Jan; Allan, Kirsten; Lee, Han; Portela, Marta; Wiede, Florian; Warr, Coral; Meng, Tzu-Ching; Tiganis, Tony; Richardson, Helena E

    2017-07-01

    Tyrosine phosphorylation-dependent signalling is coordinated by the opposing actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). There is a growing list of adaptor proteins that interact with PTPs and facilitate the dephosphorylation of substrates. The extent to which any given adaptor confers selectivity for any given substrate in vivo remains unclear. Here we have taken advantage of Drosophila melanogaster as a model organism to explore the influence of the SH3/SH2 adaptor protein Dock on the abilities of the membrane (PTP61Fm)- and nuclear (PTP61Fn)-targeted variants of PTP61F (the Drosophila othologue of the mammalian enzymes PTP1B and TCPTP respectively) to repress PTK signalling pathways in vivo. PTP61Fn effectively repressed the eye overgrowth associated with activation of the epidermal growth factor receptor (EGFR), PTK, or the expression of the platelet-derived growth factor/vascular endothelial growth factor receptor (PVR) or insulin receptor (InR) PTKs. PTP61Fn repressed EGFR and PVR-induced mitogen-activated protein kinase signalling and attenuated PVR-induced STAT92E signalling. By contrast, PTP61Fm effectively repressed EGFR- and PVR-, but not InR-induced tissue overgrowth. Importantly, coexpression of Dock with PTP61F allowed for the efficient repression of the InR-induced eye overgrowth, but did not enhance the PTP61Fm-mediated inhibition of EGFR and PVR-induced signalling. Instead, Dock expression increased, and PTP61Fm coexpression further exacerbated the PVR-induced eye overgrowth. These results demonstrate that Dock selectively enhances the PTP61Fm-mediated attenuation of InR signalling and underscores the specificity of PTPs and the importance of adaptor proteins in regulating PTP function in vivo. © 2017 Federation of European Biochemical Societies.

  15. Cyclotron production of {sup 61}Cu using natural Zn and enriched {sup 64}Zn targets

    Energy Technology Data Exchange (ETDEWEB)

    Asad, A. H.; Smith, S. V.; Chan, S.; Jeffery, C. M.; Morandeau, L.; Price, R. I. [RAPID PET Labs, Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth, Australia, Imaging and Applied Physics, Curtin University, Perth, Australia, and Center of Excellence in Anti-matter Matter Studies, Australian National University, Can (Australia); Brookhaven National Laboratory, Upton, NY (United States) and Center of Excellence in Anti-matter Matter Studies, Australian National University, Canberra (Australia); RAPID PET Labs, Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth (Australia); RAPID PET Labs, Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth (Australia); Center of Excellence in Anti-matter Matter Studies, Australian National University, Canberra, Australia, and Chemistry, University of Western Australia, Pe (Australia); RAPID PET Labs, Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth (Australia); RAPID PET Labs, Medical Technology and Physics, Sir Charles Gairdner Hospital, Perth, Australia and Physics, University of Western Australia, Perth (Australia)

    2012-12-19

    Copper-61 ({sup 61}Cu) shares with {sup 64}Cu certain advantages for PET diagnostic imaging, but has a shorter half-life (3.4hr vs. 12.7hr) and a greater probability of positron production per disintegration (61% vs. 17.9%). One important application is for in vivo imaging of hypoxic tissue. In this study {sup 61}Cu was produced using the {sup 64}Zn(p,{alpha}){sup 61}Cu reaction on natural Zn or enriched {sup 64}Zn targets. The enriched {sup 64}Zn (99.82%) was electroplated onto high purity gold or silver foils or onto thin Al discs. A typical target bombardment used 30{mu}A; at 11.7, 14.5 or 17.6MeV over 30-60min. The {sup 61}Cu (radiochemical purity of >95%) was separated using a combination of cation and anion exchange columns. The {sup 64}Zn target material was recovered after each run, for re-use. In a direct comparison with enriched {sup 64}Zn-target results, {sup 61}Cu production using the cheaper {sup nat}Zn target proved to be an effective alternative.

  16. SIRT-1 regulates TGF-β-induced dermal fibroblast migration via modulation of Cyr61 expression.

    Science.gov (United States)

    Kwon, Eun-Jeong; Park, Eun-Jung; Yu, Hyeran; Huh, Jung-Sik; Kim, Jinseok; Cho, Moonjae

    2017-07-27

    SIRT1 is a NAD-dependent protein deacetylase that participates in cellular regulation. The increased migration of fibroblasts is an important phenotype in fibroblast activation. The role of SIRT1 in cell migration remains controversial as to whether SIRT1 acts as an activator or suppressor of cell migration. Therefore, we have established the role of SIRT1 in the migration of human dermal fibroblasts and explored targets of SIRT1 during dermal fibroblast migration. SIRT1 and Cyr61 were expressed in human dermal fibroblasts and the stimulation with TGF-β further induced their expression. Treatment with resveratrol (RSV), a SIRT1 agonist, or overexpression of SIRT1 also promoted the expression Cyr61 in human dermal fibroblasts, whereas the inhibition of SIRT1 activity by nicotinamide or knockdown of SIRT1 decreased the level of Cyr61, as well as TGF-β or RSV-induced Cyr61 expression. Blocking of ERK signaling by PD98509 reduced the expression of Cyr61 induced by TGF-β or RSV. TGF-β, RSV, or SIRT1 overexpression enhanced β-catenin as well as Cyr61 expression. This stimulation was reduced by the Wnt inhibitor XAV939. RSV increased migration and nicotinamide attenuated RSV-induced migration of human dermal fibroblasts. Furthermore, SIRT1 overexpression promoted cell migration, whereas blocking Cyr61 attenuated SIRT1-stimulated migration of human dermal fibroblasts. SIRT1 increased cell migration by stimulating Cyr61 expression and the ERK and Wnt/β-catenin signaling. SIRT1-induced Cyr61 activity is very important for human dermal fibroblasts migration.

  17. 40 CFR 355.61 - How are key words in this part defined?

    Science.gov (United States)

    2010-07-01

    ... Provisions § 355.61 How are key words in this part defined? Animal waste means manure (feces, urine, and... of a technically qualified individual; or (iii) In routine agricultural operations or is a fertilizer...

  18. MT. BIGELOW 61-INCH IMAGES OF 9P/TEMPEL 1

    Data.gov (United States)

    National Aeronautics and Space Administration — This data set contains 6 images of 9P/Tempel 1 obtained on five nights in 1994 using a visual CCD mounted on the 61-inch Kuiper telescope of the Mt. Bigelow...

  19. CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer

    OpenAIRE

    Paret, Claudia; Simon, Petra; Vormbrock, Kirsten; Bender, Christian; K?lsch, Anne; Breitkreuz, Andrea; Yildiz, ?zlem; Omokoko, Tana; Hubich-Rau, Stefanie; Hartmann, Christoph; H?cker, Sabine; Wagner, Meike; Roldan, Diana Barea; Selmi, Abderaouf; T?reci, ?zlem

    2015-01-01

    Triple-negative breast cancer (TNBC) is a high medical need disease with limited treatment options. CD8+ T cell-mediated immunotherapy may represent an attractive approach to address TNBC. The objectives of this study were to assess the expression of CXorf61 in TNBCs and healthy tissues and to evaluate its capability to induce T cell responses. We show by transcriptional profiling of a broad comprehensive set of normal human tissue that CXorf61 expression is strictly restricted to testis. 53%...

  20. Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer.

    Directory of Open Access Journals (Sweden)

    Ping-Ping Chen

    Full Text Available BACKGROUND: CCN family, comprising six members (Cyr61, CTGF, Nov, WISP-1, WISP-2, WISP-3, is involved in the stimulation of cell proliferation, migration, adhesion, angiogenesis, and tumorigenesis. Several studies have shown that expression of Cyr61, CTGF, and WISP-1 affects the tumorigenic potential of lung cancer cells in vitro. However, the correlation of expression of CCN family proteins and clinical features of lung cancer remains unknown. METHODOLOGY AND PRINCIPAL FINDINGS: In the present work, we quantified the mRNA levels of Cyr61, CTGF, and WISP-1 in samples from 60 primary lung cancers and their matched normal lung tissues by quantitative real-time PCR assay. Downregulation of the Cyr61 and CTGF genes and upregulation of the WISP-1 gene were found in primary lung cancers compared to the paired normal lung tissues. Immunohistochemistry analysis also disclosed a similar expression pattern of Cyr61, CTGF, and WISP-1 protein in paired lung cancer tissues. Statistical analysis revealed significant associations between expression of either Cyr61 or CTGF with tumor stage, tumor histology, metastasis, smoking, and family history at diagnosis. A significant correlation also existed between WISP-1 expression with tumor histology, and patient age. Moreover, expression levels of Cyr61 and CTGF correlated with survival of the lung-cancer patients. CONCLUSIONS: Our results suggest that Cyr61, CTGF, and WISP-1 might be implicated in the development and progression of primary lung cancers, and their levels might serve as valuable prognostic markers, as well as potential targets for therapeutic intervention.

  1. 40 CFR 141.61 - Maximum contaminant levels for organic contaminants.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Maximum contaminant levels for organic contaminants. 141.61 Section 141.61 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER...-7 Diquat 0.02 (25) 145-73-3 Endothall 0.1 (26) 72-20-8 Endrin 0.002 (27) 1071-53-6 Glyphosate 0.7...

  2. 19 CFR 12.61 - Fur-seal or sea-otter skins permitted entry.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Fur-seal or sea-otter skins permitted entry. 12.61...; DEPARTMENT OF THE TREASURY SPECIAL CLASSES OF MERCHANDISE Fur-Seal Or Sea-Otter Skins § 12.61 Fur-seal or sea-otter skins permitted entry. (a) Fur-seal or sea-otter skins taken by Indians, Aleuts, or other...

  3. Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

    Directory of Open Access Journals (Sweden)

    Nicolai J. Wewer Albrechtsen

    2017-11-01

    Full Text Available Glucagon is secreted from pancreatic α cells, and hypersecretion (hyperglucagonemia contributes to diabetic hyperglycemia. Molecular heterogeneity in hyperglucagonemia is poorly investigated. By screening human plasma using high-resolution-proteomics, we identified several glucagon variants, among which proglucagon 1-61 (PG 1-61 appears to be the most abundant form. PG 1-61 is secreted in subjects with obesity, both before and after gastric bypass surgery, with protein and fat as the main drivers for secretion before surgery, but glucose after. Studies in hepatocytes and in β cells demonstrated that PG 1-61 dose-dependently increases levels of cAMP, through the glucagon receptor, and increases insulin secretion and protein levels of enzymes regulating glycogenolysis and gluconeogenesis. In rats, PG 1-61 increases blood glucose and plasma insulin and decreases plasma levels of amino acids in vivo. We conclude that glucagon variants, such as PG 1-61, may contribute to glucose regulation by stimulating hepatic glucose production and insulin secretion.

  4. CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer.

    Science.gov (United States)

    Paret, Claudia; Simon, Petra; Vormbrock, Kirsten; Bender, Christian; Kölsch, Anne; Breitkreuz, Andrea; Yildiz, Özlem; Omokoko, Tana; Hubich-Rau, Stefanie; Hartmann, Christoph; Häcker, Sabine; Wagner, Meike; Roldan, Diana Barea; Selmi, Abderaouf; Türeci, Özlem; Sahin, Ugur

    2015-09-22

    Triple-negative breast cancer (TNBC) is a high medical need disease with limited treatment options. CD8+ T cell-mediated immunotherapy may represent an attractive approach to address TNBC. The objectives of this study were to assess the expression of CXorf61 in TNBCs and healthy tissues and to evaluate its capability to induce T cell responses. We show by transcriptional profiling of a broad comprehensive set of normal human tissue that CXorf61 expression is strictly restricted to testis. 53% of TNBC patients express this antigen in at least 30% of their tumor cells. In CXorf61-negative breast cancer cell lines CXorf61 expression is activated by treatment with the hypomethylating agent 5-aza-2'-deoxycytidine. By vaccination of HLA-A*02-transgenic mice with CXorf61 encoding RNA we obtained high frequencies of CXorf61-specific T cells. Cloning and characterization of T cell receptors (TCRs) from responding T cells resulted in the identification of the two HLA-A*0201-restricted T cell epitopes CXorf6166-74 and CXorf6179-87. Furthermore, by in vitro priming of human CD8+ T cells derived from a healthy donor recognizing CXorf6166-74 we were able to induce a strong antigen-specific immune response and clone a human TCR recognizing this epitope. In summary, our data confirms this antigen as promising target for T cell based therapies.

  5. NA61/SHINE facility at the CERN SPS: beams and detector system

    CERN Document Server

    Abgrall, N.; Aduszkiewicz, A.; Ali, Y.; Anticic, T.; Antoniou, N.; Baatar, B.; Bay, F.; Blondel, A.; Blumer, J.; Bogomilov, M.; Bogusz, M.; Bravar, A.; Brzychczyk, J.; Bunyatov, S.A.; Christakoglou, P.; Czopowicz, T.; Davis, N.; Debieux, S.; Dembinski, H.; Diakonos, F.; Di Luise, S.; Dominik, W.; Drozhzhova, T.; Dumarchez, J.; Dynowski, K.; Engel, R.; Efthymiopoulos, I.; Ereditato, A.; Fabich, A.; Feofilov, G.A.; Fodor, Z.; Fulop, A.; Gazdzicki, M.; Golubeva, M.; Grebieszkow, K.; Grzeszczuk, A.; Guber, F.; Haesler, A.; Hasegawa, T.; Hierholzer, M.; Idczak, R.; Igolkin, S.; Ivashkin, A.; Jokovic, D.; Kadija, K.; Kapoyannis, A.; Kaptur, E.; Kielczewska, D.; Kirejczyk, M.; Kisiel, J.; Kiss, T.; Kleinfelder, S.; Kobayashi, T.; Kolesnikov, V.I.; Kolev, D.; Kondratiev, V.P.; Korzenev, A.; Koversarski, P.; Kowalski, S.; Krasnoperov, A.; Kurepin, A.; Larsen, D.; Laszlo, A.; Lyubushkin, V.V.; Maćkowiak-Pawlowska, M.; Majka, Z.; Maksiak, B.; Malakhov, A.I.; Maletic, D.; Manglunki, D.; Manic, D.; Marchionni, A.; Marcinek, A.; Marin, V.; Marton, K.; Mathes, H.J; Matulewicz, T.; Matveev, V.; Melkumov, G.L.; Messina, M.; Mrówczyński, St.; Murphy, S.; Nakadaira, T.; Nirkko, M.; Nishikawa, K.; Palczewski, T.; Palla, G.; Panagiotou, A.D.; Paul, T.; Peryt, W.; Petukhov, O.; Pistillo, C.; Planeta, R.; Pluta, J.; Popov, B.A.; Posiadala, M.; Puławski, S.; Puzovic, J.; Rauch, W.; Ravonel, M.; Redij, A.; Renfordt, R.; Richter-Was, E.; Robert, A.; Röhrich, D.; Rondio, E.; Rossi, B.; Roth, M.; Rubbia, A.; Rustamov, A.; Rybczyński, M.; Sadovsky, A.; Sakashita, K.; Savic, M.; Schmidt, K.; Sekiguchi, T.; Seyboth, P.; Sgalaberna, D.; Shibata, M.; Sipos, R.; Skrzypczak, E.; Słodkowski, M.; Sosin, Z.; Staszel, P.; Stefanek, G.; Stepaniak, J.; Stroebele, H.; Susa, T.; Szuba, M.; Tada, M.; Tereshchenko, V.; Tolyhi, T.; Tsenov, R.; Turko, L.; Ulrich, R.; Unger, M.; Vassiliou, M.; Veberic, D.; Vechernin, V.V.; Vesztergombi, G.; Vinogradov, L.; Wilczek, A.; Włodarczyk, Z.; Wojtaszek-Szwarz, A.; Wyszyński, O.; Zambelli, L.; Zipper, W.

    2014-01-01

    NA61/SHINE (SPS Heavy Ion and Neutrino Experiment) is a multi-purpose experimental facility to study hadron production in hadron-proton, hadron-nucleus and nucleus-nucleus collisions at the CERN Super Proton Synchrotron. It recorded the first physics data with hadron beams in 2009 and with ion beams (secondary 7Be beams) in 2011. NA61/SHINE has greatly profited from the long development of the CERN proton and ion sources and the accelerator chain as well as the H2 beamline of the CERN North Area. The latter has recently been modified to also serve as a fragment separator as needed to produce the Be beams for NA61/SHINE. Numerous components of the NA61/SHINE set-up were inherited from its predecessors, in particular, the last one, the NA49 experiment. Important new detectors and upgrades of the legacy equipment were introduced by the NA61/SHINE Collaboration. This paper describes the state of the NA61/SHINE facility - the beams and the detector system - before the CERN Long Shutdown I, which started in March ...

  6. BDNF Induces Striatal-Enriched Protein Tyrosine Phosphatase 61 Degradation Through the Proteasome.

    Science.gov (United States)

    Saavedra, Ana; Puigdellívol, Mar; Tyebji, Shiraz; Kurup, Pradeep; Xu, Jian; Ginés, Silvia; Alberch, Jordi; Lombroso, Paul J; Pérez-Navarro, Esther

    2016-08-01

    Brain-derived neurotrophic factor (BDNF) promotes synaptic strengthening through the regulation of kinase and phosphatase activity. Conversely, striatal-enriched protein tyrosine phosphatase (STEP) opposes synaptic strengthening through inactivation or internalization of signaling molecules. Here, we investigated whether BDNF regulates STEP levels/activity. BDNF induced a reduction of STEP61 levels in primary cortical neurons, an effect that was prevented by inhibition of tyrosine kinases, phospholipase C gamma, or the ubiquitin-proteasome system (UPS). The levels of pGluN2B(Tyr1472) and pERK1/2(Thr202/Tyr204), two STEP substrates, increased in BDNF-treated cultures, and blockade of the UPS prevented STEP61 degradation and reduced BDNF-induced GluN2B and ERK1/2 phosphorylation. Moreover, brief or sustained cell depolarization reduced STEP61 levels in cortical neurons by different mechanisms. BDNF also promoted UPS-mediated STEP61 degradation in cultured striatal and hippocampal neurons. In contrast, nerve growth factor and neurotrophin-3 had no effect on STEP61 levels. Our results thus indicate that STEP61 degradation is an important event in BDNF-mediated effects.

  7. 61 | Page

    African Journals Online (AJOL)

    Fr. Ikenga

    2016-12-10

    Dec 10, 2016 ... this in Bishak v. National Productivity Centre & Anor7 when in determining the nature of probationary employment it held that 'an officer on probation ...... Ezekiel Amakiri & Ors. (1976) 2 S.C. 1 at page 11 – 12, Casir v London North Western Railway Co. (1975). LR 10 CP. 307; Pascoe V. Turner (1979) 2 All ...

  8. Radiosynthesis and evaluation of [{sup 61}Cu]-9,10-phenanthrenequinone thiosemicarbazone in fibrosarcoma-bearing animals for PET imaging

    Energy Technology Data Exchange (ETDEWEB)

    Jalilian, A.R.; Akhlaghi, M.; Kamali-Dehghan, M.; Shafaii, K.; Moradkhani, S. [Agricultural, Medical and Industrial Research School (AMIRS-NSTRI), Karaj (Iran); Emami, A. [Islamic Azad University, Tehran (Iran). Pharmaceutical Sciences Branch

    2010-07-01

    [{sup 61}Cu]-9,10-Phenanthrenequinone thiosemicarbazone ({sup 61}Cu-PQTS), a radiolabeled anticancer compound was prepared for malignant tissue imaging studies. Copper-61 was produced via the {sup nat}Zn(p, x){sup 61}Cu nuclear reaction in a 30 MeV cyclotron (150 {mu}A irradiation for 76 min, radionuclidic purity >95%). {sup 61}Cu-PQTS was prepared from in-house synthesized PQTS. Quality control was performed using ITLC. The biodistribution of the tracer was compared to the biodistribution of cationic copper-61 in healthy controls. {sup 61}Cu-PQTS was then administered to fibrosarcoma-bearing mice for biodistribution and co-incidence imaging studies. {sup 61}Cu-PQTS demonstrated significant tumor uptake of 2.1% ID/g and the tumor was clearly visualized in a fibrosarcoma model. (orig.)

  9. Transcriptome of melanoma cells from two mouse models, Tyr:NRasQ61Kand Tyr:Rack1-HA, Tyr:NRasQ61K

    Directory of Open Access Journals (Sweden)

    Cécil Campagne

    2017-10-01

    Full Text Available The transcriptome sequencing of melanoma cells from two mouse models differing in the expression level of the scaffold protein Receptor for activated C kinase (RACK1 are presented. Primary melanoma cells were harvested from Tyr:NRasQ61K; Pax3GFP/+ mice, with or without the Tyr:Rack1-HA transgene. Cells were cultured and infected with scramble shRNA or Rack1-targeting shRNA, on technical triplicates of viral infection. Libraries were prepared by selecting polyadenylated mRNAs and RNA Sequencing (RNASeq was performed. Samples are described in the SRA portal (SRP096162 and FASTQ files have been deposited in Sequence Read Archive (accession numbers: SRR5150106 to SRR5150117. The interpretation of these data is presented in the following research article: “RACK1 cooperates with NRASQ61K to promote melanoma in vivo” (Campagne et al., 2017, doi: 10.1016/j.cellsig.2017.03.015 [1].

  10. 14 CFR 61.413 - What are the privileges of my flight instructor certificate with a sport pilot rating?

    Science.gov (United States)

    2010-01-01

    ... instructor certificate with a sport pilot rating? 61.413 Section 61.413 Aeronautics and Space FEDERAL... INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.413 What are the privileges of my flight instructor certificate with a sport pilot rating? If you hold a fight flight...

  11. 14 CFR 61.415 - What are the limits of a flight instructor certificate with a sport pilot rating?

    Science.gov (United States)

    2010-01-01

    ... certificate with a sport pilot rating? 61.415 Section 61.415 Aeronautics and Space FEDERAL AVIATION... GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.415 What are the limits of a flight instructor certificate with a sport pilot rating? If you hold a flight instructor certificate with a sport...

  12. 14 CFR 61.423 - What are the recordkeeping requirements for a flight instructor with a sport pilot rating?

    Science.gov (United States)

    2010-01-01

    ... a flight instructor with a sport pilot rating? 61.423 Section 61.423 Aeronautics and Space FEDERAL... INSTRUCTORS, AND GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.423 What are the recordkeeping requirements for a flight instructor with a sport pilot rating? (a) As a flight instructor with a...

  13. 14 CFR 61.313 - What aeronautical experience must I have to apply for a sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... apply for a sport pilot certificate? 61.313 Section 61.313 Aeronautics and Space FEDERAL AVIATION... GROUND INSTRUCTORS Sport Pilots § 61.313 What aeronautical experience must I have to apply for a sport... aeronautical experience you must have to apply for a sport pilot certificate: If you are applying for a sport...

  14. 14 CFR 61.427 - What must I do if my flight instructor certificate with a sport pilot rating expires?

    Science.gov (United States)

    2010-01-01

    ... certificate with a sport pilot rating expires? 61.427 Section 61.427 Aeronautics and Space FEDERAL AVIATION... GROUND INSTRUCTORS Flight Instructors With a Sport Pilot Rating § 61.427 What must I do if my flight instructor certificate with a sport pilot rating expires? You may exchange your expired flight instructor...

  15. 14 CFR 61.305 - What are the age and language requirements for a sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... for a sport pilot certificate? 61.305 Section 61.305 Aeronautics and Space FEDERAL AVIATION... GROUND INSTRUCTORS Sport Pilots § 61.305 What are the age and language requirements for a sport pilot certificate? (a) To be eligible for a sport pilot certificate you must: (1) Be at least 17 years old (or 16...

  16. 14 CFR 61.307 - What tests do I have to take to obtain a sport pilot certificate?

    Science.gov (United States)

    2010-01-01

    ... sport pilot certificate? 61.307 Section 61.307 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION... INSTRUCTORS Sport Pilots § 61.307 What tests do I have to take to obtain a sport pilot certificate? To obtain a sport pilot certificate, you must pass the following tests: (a) Knowledge test. You must pass a...

  17. 42 CFR 61.16 - Termination of or refusal to continue award on grounds relating to moral character or loyalty...

    Science.gov (United States)

    2010-10-01

    ... grounds relating to moral character or loyalty; hearing. 61.16 Section 61.16 Public Health PUBLIC HEALTH... Fellowships § 61.16 Termination of or refusal to continue award on grounds relating to moral character or... set forth, as specifically as security permits, the grounds for the questions pertaining to moral...

  18. File list: His.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Histone Blood Jurkat (Clone... E6-1) SRX024361,SRX024357,SRX216366 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  19. File list: DNS.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 DNase-seq Blood Jurkat (Clo...ne E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  20. File list: His.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Histone Blood Jurkat (Clone... E6-1) SRX024361,SRX216366,SRX024357 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  1. File list: DNS.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 DNase-seq Blood Jurkat (Clo...ne E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  2. File list: His.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Histone Blood Jurkat (Clone... E6-1) SRX024361,SRX024357,SRX216366 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  3. File list: Unc.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Unclassified Blood Jurkat (...Clone E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  4. File list: Unc.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Unclassified Blood Jurkat (...Clone E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  5. File list: DNS.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 DNase-seq Blood Jurkat (Clo...ne E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  6. File list: Unc.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Unclassified Blood Jurkat (...Clone E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  7. File list: His.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available His.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Histone Blood Jurkat (Clone... E6-1) SRX024361,SRX024357,SRX216366 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/His.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  8. File list: DNS.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available DNS.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 DNase-seq Blood Jurkat (Clo...ne E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/DNS.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  9. File list: Unc.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Unc.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 Unclassified Blood Jurkat (...Clone E6-1) http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Unc.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  10. 20 CFR 220.61 - Informing the examining physician or psychologist of examination scheduling, report content and...

    Science.gov (United States)

    2010-04-01

    ... psychologist of examination scheduling, report content and signature requirements. 220.61 Section 220.61... DISABILITY Consultative Examinations § 220.61 Informing the examining physician or psychologist of examination scheduling, report content and signature requirements. Consulting physicians or psychologists will...

  11. 18 CFR 366.23 - FERC Form No. 60, Annual reports of centralized service companies, and FERC-61, Narrative...

    Science.gov (United States)

    2010-04-01

    ..., Annual reports of centralized service companies, and FERC-61, Narrative description of service company... companies, and FERC-61, Narrative description of service company functions. (a) General. (1) FERC Form No... 1 each year thereafter, a narrative description, FERC-61, of the service company's functions during...

  12. 34 CFR 99.61 - What responsibility does an educational agency or institution have concerning conflict with State...

    Science.gov (United States)

    2010-07-01

    ...? § 99.61 What responsibility does an educational agency or institution have concerning conflict with... 34 Education 1 2010-07-01 2010-07-01 false What responsibility does an educational agency or institution have concerning conflict with State or local laws? 99.61 Section 99.61 Education Office of the...

  13. Dock/Nck facilitates PTP61F/PTP1B regulation of insulin signalling.

    Science.gov (United States)

    Wu, Chia-Lun; Buszard, Bree; Teng, Chun-Hung; Chen, Wei-Lin; Warr, Coral G; Tiganis, Tony; Meng, Tzu-Ching

    2011-10-01

    PTP1B (protein tyrosine phosphatase 1B) is a negative regulator of IR (insulin receptor) activation and glucose homoeostasis, but the precise molecular mechanisms governing PTP1B substrate selectivity and the regulation of insulin signalling remain unclear. In the present study we have taken advantage of Drosophila as a model organism to establish the role of the SH3 (Src homology 3)/SH2 adaptor protein Dock (Dreadlocks) and its mammalian counterpart Nck in IR regulation by PTPs. We demonstrate that the PTP1B orthologue PTP61F dephosphorylates the Drosophila IR in S2 cells in vitro and attenuates IR-induced eye overgrowth in vivo. Our studies indicate that Dock forms a stable complex with PTP61F and that Dock/PTP61F associate with the IR in response to insulin. We report that Dock is required for effective IR dephosphorylation and inactivation by PTP61F in vitro and in vivo. Furthermore, we demonstrate that Nck interacts with PTP1B and that the Nck/PTP1B complex inducibly associates with the IR for the attenuation of IR activation in mammalian cells. Our studies reveal for the first time that the adaptor protein Dock/Nck attenuates insulin signalling by recruiting PTP61F/PTP1B to its substrate, the IR.

  14. News from strong interactions program of the NA61/SHINE experiment

    CERN Document Server

    Grebieszkow, Katarzyna

    2016-01-01

    The NA61/SHINE experiment aims to discover the critical point of strongly interacting matter and study the properties of the onset of deconfinement. This is performed by a two dimensional phase diagram ($T-\\mu_B$) scan of measurements of particle spectra and fluctuations in proton-proton, proton-nucleus and nucleus-nucleus interactions as a function of collision energy and system size. In this contribution new NA61/SHINE results on negative pion production, as well as transverse momentum and multiplicity fluctuations in Ar+Sc collisions are presented. Moreover, the latest results on higher order moments of net-charge multiplicity distribution in p+p collisions are also discussed. The Ar+Sc results are compared to NA61 p+p and Be+Be data, as well as to NA49 $A+A$ results.

  15. Decreased Cyr61 under hypoxia induces extravillous trophoblasts apoptosis and preeclampsia.

    Science.gov (United States)

    Chen, Xi; Liu, Yanyan; Xu, Xiaoyan; Chen, Hanping

    2011-04-01

    During placental development, oxygen environment is not only critical for trophoblasts migration and invasion, but also fundamental for appropriate placental perfusion. Cysteine-rich 61 (Cyr61, CCN1) was expressed in the extravillous trophoblasts (EVTs) and decreased in preeclampsia. Its regulatory properties in human first-trimester extravillous trophoblast cell line (TEV-1 cells) upon a low oxygen tension were investigated. The present study examined functional changes involved in adaptation to hypoxia of the TEV-1 cells, using cobalt chloride (CoCl(2)) as hypoxic mimic. It was found that hypoxia inhibited growth of TEV-1 cells and induced the increase of cell apoptosis (Papoptosis has been implicated in the failure of trophoblasts to fully invade and modify the uterine environment and Cyr61 down-regulation, potentially leading to preeclampsia.

  16. The T61 human breast cancer xenograft: an experimental model of estrogen therapy of breast cancer

    DEFF Research Database (Denmark)

    Brunner, N; Spang-Thomsen, M; Cullen, K

    1996-01-01

    such as MCF-7 which are stimulated by estrogen. Molecular studies have demonstrated that T61 expresses easily detectable levels of mRNA for a number of peptide growth factors, including transforming growth factor alpha (TGF-alpha) and insulin-like growth factors I and II (IGF-I and IGF......-II), but not transforming growth factor beta-I (TGF-beta1). Of these, IGF-II is the only peptide whose expression is altered by endocrine therapy. Treatment of T61-bearing nude mice with physiologic doses of estrogen is accompanied by loss of IGF-II mRNA expression within 24 hours, and rapid regression of tumor. T61 tumor...

  17. Status and plans of the ion program of NA61 at the CERN SPS

    CERN Document Server

    Grebieszkow, Katarzyna

    2012-01-01

    The NA61/SHINE at the CERN SPS is a new experiment to study hadron production in h+h, h+A and A+A interactions. The main goal of the NA61 ion program is to explore the phase diagram (T - mu_B) of strongly interacting matter. In particular, we plan to study the properties of the onset of deconfinement and to search for the signatures of the critical point. A two-dimensional scan of the phase diagram will be performed by varying the energy (13A-158A GeV) and system size (p+p, Be+Be, Ar+Ca, Xe+La) of collisions. This paper summarizes the status and plans of the NA61/SHINE ion program. In particular the detector upgrades, data taking schedule and the first results on spectra and correlations are discussed.

  18. The Surface of 2003 EL61 in the Near-Infrared

    Science.gov (United States)

    Trujillo, Chadwick A.; Brown, Michael E.; Barkume, Kristina M.; Schaller, Emily L.; Rabinowitz, David L.

    2007-02-01

    We report the detection of crystalline water ice on the surface of 2003 EL61. Reflectance spectra were collected from the Gemini North telescope in the 1.0 to 2.4 μm wavelength range and from the Keck telescope across the 1.4-2.4 μm wavelength range. The signature of crystalline water ice is obvious in all data collected. Like the surfaces of many outer solar system bodies, the surface of 2003 EL61 is rich in crystalline water ice, which is energetically less favored than amorphous water ice at low temperatures, suggesting that resurfacing processes may be taking place. The near-infrared color of the object is much bluer than a pure water ice model. Adding a near-infrared blue component such as hydrogen cyanide or phyllosilicate clays improves the fit considerably, with hydrogen cyanide providing the greatest improvement. The addition of hydrated tholins and bitumens also improves the fit, but is inconsistent with the neutral V-J reflectance of 2003 EL61. A small decrease in reflectance beyond 2.3 μm may be attributable to cyanide salts. Overall, the reflected light from 2003 EL61 is best fit by a model of 2/3-4/5 pure crystalline water ice and 1/3-1/5 near-infrared blue component such as hydrogen cyanide or kaolinite. The surface of 2003 EL61 is unlikely to be covered by significant amounts of dark material such as carbon black, as our pure ice models reproduce published albedo estimates derived from the spin state of 2003 EL61.

  19. Der Hundertjährige Krieg (1558-1660/61) in Estland / Margus Laidre

    Index Scriptorium Estoniae

    Laidre, Margus, 1959-

    2006-01-01

    Ülemvõimu pärast Läänemerel peetud sõdade perioodist, mida autor nimetaks Eesti ajaloo Saja-aastaseks sõjaks (1558-1660/61), mis jaguneks : 1) Vene-Liivi etapp 1558-1562, 2) Taani-Poola etapp 1563-1570, 3) Vene etapp 1570-1595, 4) 1595-1599 vaheetapp, 5) 1600-1629 "kolmekümneaastane sõda Rootsi ja Poola vahel, 6) 1629-1654 vaherahude etapp, 1655-1660/61 Rootsi triumf. Eesti rahvastiku suurusest 16.-18. sajandil

  20. Thermal neutron capture γ-ray spectroscopy of59Ni and61Ni

    Science.gov (United States)

    Harder, A.; Michaelsen, S.; Lieb, K. P.; Williams, A. P.

    1993-06-01

    The γ-radiation emitted after thermal neutron capture in isotopically enriched58Ni and60Ni was measured at the ILL high flux reactor by means of Ge/NaI detectors operated in Compton suppression and pair spectrometer mode. The neutron binding energies were determined as B n (59Ni)=8999.15(23) keV and Bn(61Ni)=7820.07(20) keV; some 95% of the total γ-ray fluxes through59,61Ni were assigned. The γ-ray strength functions of the primary transitions and the level densities are discussed.

  1. Beethoven, Ludwig van: Concerto pour violon op. 61 / Jean-Michel Molkhou

    Index Scriptorium Estoniae

    Molkhou, Jean-Michel

    1997-01-01

    Uuest heliplaadist "Beethoven, Ludwig van: Concerto pour violon op. 61 (cadence Schnittke). Les 2 Romances op. 40 et 50. Orchestre Symphonique National d'Estonie, Arvo Volmer" Globe GLO 5155, distribution Talis (CD:153F). 1996. TT:1h 01'56"

  2. 22 CFR 51.61 - Denial of passports to certain convicted drug traffickers.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Denial of passports to certain convicted drug... Denial, Revocation, and Restriction of Passports § 51.61 Denial of passports to certain convicted drug... felony conviction for a Federal or state drug offense, if the individual used a U.S. passport or...

  3. 49 CFR 393.61 - Truck and truck tractor window construction.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Truck and truck tractor window construction. 393... REGULATIONS PARTS AND ACCESSORIES NECESSARY FOR SAFE OPERATION Glazing and Window Construction § 393.61 Truck and truck tractor window construction. Each truck and truck tractor (except trucks engaged in armored...

  4. Private and Commercial Pilot: Ligher-Than-Air Airship. Flight Test Guide. (Part 61 Revised).

    Science.gov (United States)

    Federal Aviation Administration (DOT), Washington, DC. Flight Standards Service.

    The flight test guide assists the applicant and his instructor in preparing for the flight test for the Private or Commercial Pilot Certificate with a Lighter-Than-Air Category and Airship Class Rating under Part 61 (revised) of Federal Aviation Regulations. It contains information and guidance concerning pilot operations, procedures, and…

  5. 14 CFR 61.5 - Certificates and ratings issued under this part.

    Science.gov (United States)

    2010-01-01

    ...) Recreational pilot. (iv) Private pilot. (v) Commercial pilot. (vi) Airline transport pilot. (2) Flight... two pilots. (8) Instrument ratings (on private and commercial pilot certificates only)— (i) Instrument... TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61...

  6. 40 CFR 61.184 - Ambient air monitoring for inorganic arsenic.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Ambient air monitoring for inorganic... for Inorganic Arsenic Emissions From Arsenic Trioxide and Metallic Arsenic Production Facilities § 61.184 Ambient air monitoring for inorganic arsenic. (a) The owner or operator of each source to which...

  7. Deep Chandra observations of TeV binaries : I. LSI+61°303

    NARCIS (Netherlands)

    Rea, N.; Torres, D. F.; van der Klis, M.; Jonker, P.G.; Mendez, M.; Sierpowska-Bartosik, A.

    2010-01-01

    We report on a 95 ks Chandra observation of the TeV emitting high-mass X-ray binary LS I +61 degrees 303, using the ACIS-S camera in continuous clocking mode to search for a possible X-ray pulsar in this system. The observation was performed while the compact object was passing from phase 0.94 to

  8. 38 CFR 61.53 - Rating criteria for technical assistance grant applications.

    Science.gov (United States)

    2010-07-01

    ... DEPARTMENT OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.53 Rating... homeless veterans; (2) Ability to find and offer technical assistance to entities eligible for such... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Rating criteria for...

  9. 38 CFR 61.12 - Threshold requirements for capital grant applications.

    Science.gov (United States)

    2010-07-01

    ... OF VETERANS AFFAIRS (CONTINUED) VA HOMELESS PROVIDERS GRANT AND PER DIEM PROGRAM § 61.12 Threshold... population proposed to be served is homeless veterans; (d) The activities for which assistance is requested... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Threshold requirements...

  10. 14 CFR 61.3 - Requirement for certificates, ratings, and authorizations.

    Science.gov (United States)

    2010-01-01

    ... current medical qualification for that license; or (xi) Is operating an aircraft with a U.S. pilot... TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61... serve as a required pilot flight crewmember of a civil aircraft of the United States, unless that person...

  11. Howland Island Site 5P 3/17/2000 61-62M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Howland Island, site 5P (00 48.340 N, 176 37.272 W), between 61 and 62 meters along a permanent transect.

  12. Looking for the phase transition - recent NA61/SHINE results arXiv

    CERN Document Server

    Turko, Ludwik

    The fixed-target NA61/SHINE experiment (SPS CERN) looks for the critical point of strongly interacting matter and the properties of the onset of deconfinement. It is a two dimensional scan of measurements of particle spectra and fluctuations in proton-proton, proton-nucleus and nucleus-nucleus interactions as a function of collision energy and system size, corresponding to a two dimensional phase diagram (temperature T - baryonic chemical potential $\\mu_B$). New NA61/SHINE results are presented here, such as transverse momentum and multiplicity fluctuations in Ar+Sc collisions compared to NA61/SHINE p+p and Be+Be data, as well as to earlier NA49 A+A results. Recently, a preliminary signature for the new size dependent effect - rapid changes in system size dependence was observed in NA61-SHINE data, labeled as percolation threshold or onset of fireball. This would be closely related to the vicinity of the hadronic phase transition region.

  13. 40 CFR 230.61 - Chemical, biological, and physical evaluation and testing.

    Science.gov (United States)

    2010-07-01

    ... FILL MATERIAL Evaluation and Testing § 230.61 Chemical, biological, and physical evaluation and testing...-biological interactive effects. Dredged or fill material may be excluded from the evaluation procedures... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Chemical, biological, and physical...

  14. A structural overview of GH61 proteins – fungal cellulose degrading polysaccharide monooxygenases

    Directory of Open Access Journals (Sweden)

    Leila Lo Leggio

    2012-09-01

    Full Text Available Recent years have witnessed a spurt of activities in the elucidation of the molecular function of a class of proteins with great potential in biomass degradation. GH61 proteins are of fungal origin and were originally classified in family 61 of the glycoside hydrolases. From the beginning they were strongly suspected to be involved in cellulose degradation because of their expression profiles, despite very low detectable endoglucanase activities. A major breakthrough came from structure determination of the first members, establishing the presence of a divalent metal binding site and a similarity to bacterial proteins involved in chitin degradation. A second breakthrough came from the identification of cellulase boosting activity dependent on the integrity of the metal binding site. Finally very recently GH61 proteins were demonstrated to oxidatively cleave crystalline cellulose in a Cu and reductant dependant manner. This mini-review in particular focuses on the contribution that structure elucidation has made in the understanding of GH61 molecular function and reviews the currently known structures and the challenges remaining ahead for exploiting this new class of enzymes to the full.

  15. A STRUCTURAL OVERVIEW OF GH61 PROTEINS – FUNGAL CELLULOSE DEGRADING POLYSACCHARIDE MONOOXYGENASES

    Directory of Open Access Journals (Sweden)

    Leila Lo Leggio

    2012-09-01

    Full Text Available Recent years have witnessed a spurt of activities in the elucidation of the molecular function of a class of proteins with great potential in biomass degradation. GH61 proteins are of fungal origin and were originally classified in family 61 of the glycoside hydrolases. From the beginning they were strongly suspected to be involved in cellulose degradation because of their expression profiles, despite very low detectable endoglucanase activities. A major breakthrough came from structure determination of the first members, establishing the presence of a divalent metal binding site and a similarity to bacterial proteins involved in chitin degradation. A second breakthrough came from the identification of cellulase boosting activity dependent on the integrity of the metal binding site. Finally very recently GH61 proteins were demonstrated to oxidatively cleave crystalline cellulose in a Cu and reductant dependant manner. This mini-review in particular focuses on the contribution that structure elucidation has made in the understanding of GH61 molecular function and reviews the currently known structures and the challenges remaining ahead for exploiting this new class of enzymes to the full.

  16. 40 CFR 61.43 - Emission testing-rocket firing or propellant disposal.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Emission testing-rocket firing or... Standard for Beryllium Rocket Motor Firing § 61.43 Emission testing—rocket firing or propellant disposal. (a) Ambient air concentrations shall be measured during and after firing of a rocket motor or...

  17. I korabl plõvjot... Uzhe v 61-i raz / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2008-01-01

    Peatselt algavast Cannes'i 61. filmifestivalist, võistlusprogrammist. Eesti osaleb filmiturul nelja filmiga : "Georg", "Sügisball", Kuhu põgenevad hinged", "Mina olin siin" ning lisaks Ukraina-Eesti koostööfilm "Kurja saatuse mängukannid" ("Prikalna kazka"). Veiko Õunpuu saab festivali käigus kätte Euroopa Talendi auhinna

  18. 27 CFR 70.61 - Payment by check or money order.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Payment by check or money... Collection of Excise and Special (Occupational) Tax Receipt of Payment § 70.61 Payment by check or money... State, Territory, or possession of the United States, or money orders in payment for internal revenue...

  19. 14 CFR 61.163 - Aeronautical experience: Powered-lift category rating.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Aeronautical experience: Powered-lift... Transport Pilots § 61.163 Aeronautical experience: Powered-lift category rating. (a) A person who is applying for an airline transport pilot certificate with a powered-lift category rating must have at least...

  20. 49 CFR 230.61 - Arch tubes, water bar tubes, circulators and thermic siphons.

    Science.gov (United States)

    2010-10-01

    ... (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION STEAM LOCOMOTIVE INSPECTION AND MAINTENANCE STANDARDS Boilers and Appurtenances Washing Boilers § 230.61 Arch tubes, water bar tubes, circulators and thermic siphons. (a) Frequency of cleaning. Each time the boiler is washed, arch tubes and...

  1. 42 CFR 414.61 - Payment for anesthesia services furnished by a teaching CRNA.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Payment for anesthesia services furnished by a... SERVICES Physicians and Other Practitioners § 414.61 Payment for anesthesia services furnished by a teaching CRNA. (a) Basis for payment. Beginning January 1, 2010, anesthesia services furnished by a...

  2. Comparison of LLW Disposal Performance Objectives 10 CFR 61 and DOE 435.1

    Energy Technology Data Exchange (ETDEWEB)

    Wilhite, E.L.

    2001-03-28

    This report documents that waste disposed according to DOE M 435.1 requirements for LLW disposal (i.e., performance, objectives, performance assessment (PA), waste characterization, and other requirements) meets safety requirements comparable to the 10 CFR 61 performance objectives.

  3. 20 CFR 219.61 - Evidence of where the employee had a permanent home.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of where the employee had a... RAILROAD RETIREMENT ACT EVIDENCE REQUIRED FOR PAYMENT Other Evidence Requirements § 219.61 Evidence of where the employee had a permanent home. The Board will ask for the following evidence to establish the...

  4. 14 CFR 61.197 - Renewal requirements for flight instructor certification.

    Science.gov (United States)

    2010-01-01

    ... Instructors Other than Flight Instructors With a Sport Pilot Rating § 61.197 Renewal requirements for flight... the following renewal requirements— (i) A record of training students showing that, during the... completed an approved flight instructor refresher course consisting of ground training or flight training...

  5. 45 CFR 86.61 - Sex as a bona-fide occupational qualification.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Sex as a bona-fide occupational qualification. 86... NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 86.61 Sex as a...

  6. 34 CFR 106.61 - Sex as a bona-fide occupational qualification.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Sex as a bona-fide occupational qualification. 106.61..., DEPARTMENT OF EDUCATION NONDISCRIMINATION ON THE BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or...

  7. CXorf61 is a target for T cell based immunotherapy of triple-negative breast cancer

    National Research Council Canada - National Science Library

    Paret, Claudia; Simon, Petra; Vormbrock, Kirsten; Bender, Christian; Kölsch, Anne; Breitkreuz, Andrea; Yildiz, Özlem; Omokoko, Tana; Hubich-Rau, Stefanie; Hartmann, Christoph; Häcker, Sabine; Wagner, Meike; Roldan, Diana Barea; Selmi, Abderaouf; Türeci, Özlem; Sahin, Ugur

    2015-01-01

    ...+ T cell-mediated immunotherapy may represent an attractive approach to address TNBC. The objectives of this study were to assess the expression of CXorf61 in TNBCs and healthy tissues and to evaluate its capability to induce T cell responses...

  8. 14 CFR 61.59 - Falsification, reproduction, or alteration of applications, certificates, logbooks, reports, or...

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Falsification, reproduction, or alteration...: PILOTS, FLIGHT INSTRUCTORS, AND GROUND INSTRUCTORS General § 61.59 Falsification, reproduction, or... authorization under this part; (3) Any reproduction for fraudulent purpose of any certificate, rating, or...

  9. A homotetrameric kinesin-5, KLP61F, bundles microtubules and antagonizes Ncd in motility assays.

    Science.gov (United States)

    Tao, Li; Mogilner, Alex; Civelekoglu-Scholey, Gul; Wollman, Roy; Evans, James; Stahlberg, Henning; Scholey, Jonathan M

    2006-12-05

    Mitosis depends upon the cooperative action of multiple microtubule (MT)-based motors. Among these, a kinesin-5, KLP61F, and the kinesin-14, Ncd, are proposed to generate antagonistic-sliding forces that control the spacing of the spindle poles. We tested whether purified KLP61F homotetramers and Ncd homodimers can generate a force balance capable of maintaining a constant spindle length in Drosophila embryos. Using fluorescence microscopy and cryo-EM, we observed that purified full-length, motorless, and tailless KLP61F tetramers (containing a tetramerization domain) and Ncd dimers can all cross-link MTs into bundles in MgATP. In multiple-motor motility assays, KLP61F and Ncd drive plus-end and minus-end MT sliding at 0.04 and 0.1 microm/s, respectively, but the motility of either motor is decreased by increasing the mole fraction of the other. At the "balance point," the mean velocity was zero and MTs paused briefly and then oscillated, taking approximately 0.3 microm excursions at approximately 0.02 microm/s toward the MT plus end and then the minus end. The results, combined with quantitative analysis, suggest that these motors could act as mutual brakes to modulate the rate of pole-pole separation and could maintain a prometaphase spindle displaying small fluctuations in its steady-state length.

  10. 14 CFR 61.199 - Reinstatement requirements of an expired flight instructor certificate.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Reinstatement requirements of an expired... GROUND INSTRUCTORS Flight Instructors Other than Flight Instructors With a Sport Pilot Rating § 61.199 Reinstatement requirements of an expired flight instructor certificate. (a) Flight instructor certificates. The...

  11. 14 CFR 61.31 - Type rating requirements, additional training, and authorization requirements.

    Science.gov (United States)

    2010-01-01

    ... aspects of high-altitude flight. (2) Except as provided in paragraph (g)(3) of this section, no person may... certificate operating under the provisions of § 61.101(h); or (vi) The holder of a sport pilot certificate when operating a light-sport aircraft. ...

  12. 14 CFR 61.69 - Glider and unpowered ultralight vehicle towing: Experience and training requirements.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Glider and unpowered ultralight vehicle... GROUND INSTRUCTORS Aircraft Ratings and Pilot Authorizations § 61.69 Glider and unpowered ultralight... a glider or unpowered ultralight vehicle unless that person— (1) Holds a private, commercial or...

  13. Extraction du complexe (𕔣P 2 W 17 O 61 Fe)7-, par ...

    African Journals Online (AJOL)

    membrane The extraction of a Dawson-type heteropolyanion (∝1P2W17O61Fe) 7- was carried out by liquid surfactant membrane using (SPAN80) as surfactantand (TIBA) as extractant, internal phase used (NH4)2CO3. The extraction efficiency is 90 %. Then in order to regenerate the membrane, the stripping efficiency was ...

  14. 25 CFR 12.61 - Can I be paid for information that helps solve a crime?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Can I be paid for information that helps solve a crime... COUNTRY LAW ENFORCEMENT Support Functions § 12.61 Can I be paid for information that helps solve a crime... investigation of a crime. This is subject to the availability of funds. This authority may be delegated in...

  15. 40 CFR 61.242-9 - Standards: Surge control vessels and bottoms receivers.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Standards: Surge control vessels and... Emission Standard for Equipment Leaks (Fugitive Emission Sources) § 61.242-9 Standards: Surge control vessels and bottoms receivers. Each surge control vessel or bottoms receiver that is not routed back to...

  16. Study of S1 detector' time resolution at NA61/SHINE experiment

    CERN Document Server

    Balkova, Yuliia

    2017-01-01

    This document presents the final report on my project at CERN Summer Student Programme. The aim of the work was to determine time resolution of S1 (scintillation) detector at NA61/SHINE experiment's beamline and how it depends on readout voltage, beam size and beam position.

  17. 22 CFR 61.8 - Coordination with United States Customs Service.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Coordination with United States Customs Service... FREE FLOW OF AUDIO-VISUAL MATERIALS § 61.8 Coordination with United States Customs Service. (a) Nothing in this part shall preclude examination of imported materials pursuant to the Customs laws and...

  18. 32 CFR 1605.61 - Staff of area offices for selective service.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Staff of area offices for selective service... SERVICE SYSTEM SELECTIVE SERVICE SYSTEM ORGANIZATION Area Office Administration § 1605.61 Staff of area... staff of each area office shall consist of as many compensated employees, either military or civilian...

  19. Operation and performance of Time Projection Chambers of SHINE / NA61 experiment at CERN

    CERN Document Server

    Aduszkiewicz, Antoni

    This paper characterizes the Time Projection Chambers (TPC) in the SHINE / NA61 exper- iment at CERN and their operation during the first run in 2007. An analysis of a change of the gas mixture in the TPCs for SHINE is included. Also the gas system of the TPCs is described.

  20. Inhibition of STEP61 ameliorates deficits in mouse and hiPSC-based schizophrenia models

    Science.gov (United States)

    Xu, Jian; Phillips, Andre; Topol, Aaron; Xu, Meiyu; Ononenyi, Chimezie; Foscue, Ethan; Ho, Seok-Man; Baguley, Tyler D.; Carty, Nikisha; Barros, Claudia S.; Müller, Ulrich; Gupta, Sounak; Gochman, Peter A.; Rapoport, Judith; Ellman, Jonathan A.; Pittenger, Christopher; Aronow, Bruce; Nairn, Angus C.; Nestor, Michael W.; Lombroso, Paul J.; Brennand, Kristen J.

    2016-01-01

    The brain-specific tyrosine phosphatase, STEP (STriatal-Enriched protein tyrosine Phosphatase) is an important regulator of synaptic function. STEP normally opposes synaptic strengthening by increasing N-methyl D-aspartate glutamate receptors (NMDARs) internalization through dephosphorylation of GluN2B and inactivation of the kinases ERK1/2 and Fyn. Here we show that STEP61 is elevated in the cortex in the Nrg1+/− knockout mouse model of SZ. Genetic reduction or pharmacological inhibition of STEP prevents the loss of NMDA receptors from synaptic membranes and reverses behavioral deficits in Nrg1+/− mice. STEP61 protein is also increased in cortical lysates from the CNS-specific ErbB2/4 mouse model of SZ, as well as in human induced pluripotent stem cell (hiPSC)-derived forebrain neurons and Ngn2-induced excitatory neurons from two independent SZ patient cohorts. In these selected SZ models, increased STEP61 protein levels likely reflect reduced ubiquitination and degradation. These convergent findings from mouse and hiPSC SZ models provide evidence for STEP61 dysfunction in SZ. PMID:27752082

  1. 49 CFR 37.61 - Public transportation programs and activities in existing facilities.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Public transportation programs and activities in... TRANSPORTATION SERVICES FOR INDIVIDUALS WITH DISABILITIES (ADA) Transportation Facilities § 37.61 Public transportation programs and activities in existing facilities. (a) A public entity shall operate a designated...

  2. 28 CFR 513.61 - Freedom of Information Act requests by inmates.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Freedom of Information Act requests by... MANAGEMENT AND ADMINISTRATION ACCESS TO RECORDS Release of Information Freedom of Information Act Requests for Information § 513.61 Freedom of Information Act requests by inmates. (a) Inmates are encouraged to...

  3. 45 CFR 61.10 - Reporting exclusions from participation in Federal or State health care programs.

    Science.gov (United States)

    2010-10-01

    ... ON HEALTH CARE PROVIDERS, SUPPLIERS AND PRACTITIONERS Reporting of Information § 61.10 Reporting... State Government agencies must report health care providers, suppliers, or practitioners excluded from... relationship to each associated or affiliated health care entity. (3) If the subject is an organization...

  4. Early start of progressive motor deficits in Line 61 α-synuclein transgenic mice.

    Science.gov (United States)

    Rabl, R; Breitschaedel, C; Flunkert, S; Duller, S; Amschl, D; Neddens, J; Niederkofler, V; Rockenstein, E; Masliah, E; Roemer, H; Hutter-Paier, B

    2017-01-31

    Synucleinopathies such as Parkinson's disease or multiple system atrophy are characterized by Lewy bodies in distinct brain areas. These aggregates are mainly formed by α-synuclein inclusions, a protein crucial for synaptic functions in the healthy brain. Transgenic animal models of synucleinopathies are frequently based on over-expression of human wild type or mutated α-synuclein under the regulatory control of different promoters. A promising model is the Line 61 α-synuclein transgenic mouse that expresses the transgene under control of the Thy-1 promoter. Here, we show an extended characterization of this mouse model over age. To this end, we analyzed animals for the progression of human and mouse protein expression levels in different brain areas as well as motor and memory deficits. Our results show, that Line 61 mice exhibited an age dependent increase of α-synuclein protein levels in the hippocampus but not the striatum. While murine α-synuclein was also increased with age, it was lower expressed in Line 61 mice than in non-transgenic littermates. At the age of 9 months animals exhibited increased neuroinflammation. Furthermore, we found that Line 61 mice showed severe motor deficits as early as 1 month of age as assessed by the wire hanging and nest building tests. At later ages, initial motor deficits were validated with the RotaRod, pasta gnawing and beam walk tests. At 8 months of age animals exhibited emotional memory deficits as validated with the contextual fear conditioning test. In summary, our results strengthen and further expand our knowledge about the Line 61 mouse model, emphasizing this mouse model as a valuable in vivo tool to test new compounds directed against synucleinopathies.

  5. Inhibition of striatal-enriched tyrosine phosphatase 61 in the dorsomedial striatum is sufficient to increased ethanol consumption.

    Science.gov (United States)

    Darcq, Emmanuel; Hamida, Sami Ben; Wu, Su; Phamluong, Khanky; Kharazia, Viktor; Xu, Jian; Lombroso, Paul; Ron, Dorit

    2014-06-01

    The STriatal-Enriched protein tyrosine Phosphatase 61 (STEP61 ) inhibits the activity of the tyrosine kinase Fyn and dephosphorylates the GluN2B subunit of the NMDA receptor, whereas the protein kinase A phosphorylation of STEP61 inhibits the activity of the phosphatase (Pharmacol. Rev., 64, , p. 65). Previously, we found that ethanol activates Fyn in the dorsomedial striatum (DMS) leading to GluN2B phosphorylation, which, in turn, underlies the development of ethanol intake (J. Neurosci., 30, , p. 10187). Here, we tested the hypothesis that inhibition of STEP61 by ethanol is upstream of Fyn/GluN2B. We show that exposure of mice to ethanol increased STEP61 phosphorylation in the DMS, which was maintained after withdrawal and was not observed in other striatal regions. Specific knockdown of STEP61 in the DMS of mice enhanced ethanol-mediated Fyn activation and GluN2B phosphorylation, and increased ethanol intake without altering the level of water, saccharine, quinine consumption or spontaneous locomotor activity. Together, our data suggest that blockade of STEP61 activity in response to ethanol is sufficient for the activation of the Fyn/GluN2B pathway in the DMS. Being upstream of Fyn and GluN2B, inactive STEP61 in the DMS primes the induction of ethanol intake. We show that ethanol-mediated inhibition of STEP61 in the DMS leads to Fyn activation and GluN2B phosphorylation. (a) Under basal conditions, active STEP61 inhibits Fyn activity and dephosphorylates GluN2B. (b) Ethanol leads to the phosphorylation of STEP61 on a specific inhibitory site. The inhibition of STEP61 activity contributes to the activation of Fyn in response to ethanol, which, in turn, phosphorylates GluN2B. These molecular adaptations in the DMS promote ethanol drinking. © 2014 International Society for Neurochemistry.

  6. Expressions of Cyr61 and WISP-3 in Non-small Cell Lung Cancer and Its Clinical Significance

    Directory of Open Access Journals (Sweden)

    Jianfa LV

    2010-12-01

    Full Text Available Background and objective Cysteine-rich protein 61 (Cyr61 plays a role as a tumor suppressor in non-small cell lung cancer (NSCLC. Cyr61 and WISP-3 have a very significant sequence homology, belonging to the same CCN gene family. The aim of this study is to investigate the expressions of Cyr61 and WISP-3 in NSCLC, and explore the relationship between their expressions and tumor's clinicopathological characteristics. Methods The expressions of Cyr61 and WISP-3 were detected in 54 cases with primary NSCLC and their corresponding normal lung tissues in control group by immunohistochemical staining (SP, and the clinical data were analyzed. Results Down-regulation of Cyr61 and up-regulation of WISP-3 were both found in lung cancer tissue compared with the corresponding normal lung tissue (both P < 0.001; The expression of Cyr61 was negatively correlated with the expression of WISP-3 (r=-0.395, P=0.003; Cyr61 expression levels was closely correlated with tumor grade, tumor type, clinical stage, family history, smoking and metastasis (P < 0.05. Also, WISP-3 was closely correlated with tumor grade, clinical stage and age (P < 0.05. Conclusion The expressions of Cyr61 and/or WISP-3 may be important biological markers in reflecting the progression, biological behaviors, metastatic potential and prognosis of NSCLC.

  7. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61.

    Science.gov (United States)

    Kurup, Pradeep; Zhang, Yongfang; Xu, Jian; Venkitaramani, Deepa V; Haroutunian, Vahram; Greengard, Paul; Nairn, Angus C; Lombroso, Paul J

    2010-04-28

    Amyloid beta (Abeta) is involved in the etiology of Alzheimer's disease (AD) and may contribute to cognitive deficits by increasing internalization of ionotropic glutamate receptors. Striatal-enriched protein tyrosine phosphatase 61 (STEP(61)), which is targeted in part to the postsynaptic terminal, has been implicated in this process. Here we show that STEP(61) levels are progressively increased in the cortex of Tg2576 mice over the first year, as well as in prefrontal cortex of human AD brains. The increased STEP(61) was associated with greater STEP activity, dephosphorylation of phospho-tyr(1472) of the NR2B subunit, and decreased NR1 and NR2B subunits on neuronal membranes. Treatment with Abeta-enriched medium also increased STEP(61) levels and decreased NR1/NR2B abundance in mouse cortical cultures as determined by biotinylation experiments. In STEP knock-out cultures, Abeta treatment failed to induce NMDA receptor internalization. The mechanism for the increase in STEP(61) levels appears to involve the ubiquitin proteasome system. Blocking the proteasome resulted in elevated levels of STEP(61). Moreover, STEP(61)-ubiquitin conjugates were increased in wild-type cortical slices upon Abeta treatment as well as in 12 month Tg2576 cortex. These findings reveal a novel mechanism by which Abeta-mediated accumulation of STEP(61) results in increased internalization of NR1/NR2B receptor that may contribute to the cognitive deficits in AD.

  8. Aβ–mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61

    Science.gov (United States)

    Kurup, Pradeep; Zhang, Yongfang; Xu, Jian; Venkitaramani, Deepa V.; Haroutunian, Vahram; Greengard, Paul; Nairn, Angus C.; Lombroso, Paul J.

    2010-01-01

    Amyloid beta (Aβ) is involved in the etiology of Alzheimer's disease (AD) and may contribute to cognitive deficits by increasing internalization of ionotropic glutamate receptors. STriatal-Enriched protein tyrosine Phosphatase 61 (STEP61), which is targeted in part to the postsynaptic terminal, has been implicated in this process. Here we show that STEP61 levels are progressively increased in the cortex of Tg2576 mice over the first year, as well as in prefrontal cortex of human AD brains. The increased STEP61 was associated with greater STEP activity, dephosphorylation of phospho-tyr1472 of the NR2B subunit, and decreased NR1 and NR2B subunits on neuronal membranes. Treatment with Aβ~-enriched medium also increased STEP61 levels and decreased NR1/NR2B abundance in mouse cortical cultures as determined by biotinylation experiments. In STEP knock-out cultures, Aβ treatment failed to induce NMDAR internalization. The mechanism for the increase in STEP61 levels appears to involve the ubiquitin proteasome system (UPS). Blocking the proteasome resulted in elevated levels of STEP61. Moreover, STEP61-ubiquitin conjugates were increased in wild-type cortical slices upon Aβ treatment as well as in 12-month Tg2576 cortex. These findings reveal a novel mechanism by which Aβ-mediated accumulation of STEP61 results in increased internalization of NR1/NR2B receptor that may contribute to the cognitive deficits in AD. PMID:20427654

  9. Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors during homeostatic synaptic plasticity.

    Science.gov (United States)

    Jang, Sung-Soo; Royston, Sara E; Xu, Jian; Cavaretta, John P; Vest, Max O; Lee, Kwan Young; Lee, Seungbae; Jeong, Han Gil; Lombroso, Paul J; Chung, Hee Jung

    2015-09-22

    Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate receptors (NMDAR) and α-amino-3-hydroxyle-5-methyl-4-isoxazolepropionic acid receptors (AMPAR), which are primary mediators of excitatory synaptic transmission. A key trafficking modulator of NMDAR and AMPAR is STriatal-Enriched protein tyrosine Phosphatase (STEP61) that opposes synaptic strengthening through dephosphorylation of NMDAR subunit GluN2B and AMPAR subunit GluA2. However, the role of STEP61 in homeostatic synaptic plasticity is unknown. We demonstrate here that prolonged activity blockade leads to synaptic scaling, and a concurrent decrease in STEP61 level and activity in rat dissociated hippocampal cultured neurons. Consistent with STEP61 reduction, prolonged activity blockade enhances the tyrosine phosphorylation of GluN2B and GluA2 whereas increasing STEP61 activity blocks this regulation and synaptic scaling. Conversely, prolonged activity enhancement increases STEP61 level and activity, and reduces the tyrosine phosphorylation and level of GluN2B as well as GluA2 expression in a STEP61-dependent manner. Given that STEP61-mediated dephosphorylation of GluN2B and GluA2 leads to their internalization, our results collectively suggest that activity-dependent regulation of STEP61 and its substrates GluN2B and GluA2 may contribute to homeostatic stabilization of excitatory synapses.

  10. Radioanalytical technology for 10 CFR Part 61 and other selected radionuclides: Literature review

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, C.W.; Thomas, V.W.; Robertson, D.E. [Pacific Northwest National Lab., Richland, WA (United States)

    1996-03-01

    A comprehensive literature review and assessment was conducted to identify and evaluate radioanalytical technology and procedures used for measuring 10CFR61 radionuclides and other long-lived isotopes. This review evaluated radiochemical procedures currently in use at a number of laboratories in the US, as well as identifying new advanced methods and techniques which could be adapted for routine radiochemical analyses of low-level radioactive waste. The 10CFR61 radionuclides include {sup 14}C, {sup 60}Cl, {sup 59,63}Ni, {sup 90}Sr, {sup 94}Nb, {sup 99}Tc, {sup 129}I, {sup 137}Cs, and TRU isotopes with half lives greater than 5 years. Other low-level radionuclides of interest include {sup 7,10}Be, {sup 26}Al, {sup 36}Cl, {sup 93}Mo, {sup 109,113m}Cd, and {sup 121m,126}Sn, which may be present in various types of waste streams from nuclear power stations.

  11. Krypton calibration of time projection chambers of the NA61/SHINE experiment

    CERN Document Server

    Naskret, Michal

    The NA61/SHINE experiment at CERN is searching for the critical point in phase transition between quark-gluon plasma and hadronic matter. To do so we use the most precise apparatus - Time Projection Chamber. Its main task is to find trajectories of particles created in a relativistic collision. In order to improve efficiency of TPCs, we introduce calibration using radioactive krypton gas. Simulation of events in a TPC cham- ber through a decay of excited krypton atoms gives us a spectrum, which is later fitted to the model spectrum of krypton from a Monte-Carlo simulation. The data obtained in such a way serves us to determine malfunctioning electronics in TPCs. Thanks to the krypton calibration we can create a map of pad by pad gains. In this thesis I will de- scribe in detail the NA61 experimental setup, krypton calibration procedure, calibration algorithm and results for recent calibration runs

  12. News on mean pion multiplicity from NA61/SHINE arXiv

    CERN Document Server

    NA61/SHINE is a large acceptance fixed target experiment at the CERN SPS which studies final hadronic states in interactions between various particles and nuclei. The main topic of this contribution are preliminary results for mean negatively charged pion multiplicities $\\langle \\pi^{-} \\rangle$ from central Ar+Sc and Be+Be collisions. The data were taken recently by the NA61/SHINE collaboration for a wide range of beam momenta. Measured rapidity distributions $\\frac{dn}{dy}$ were extrapolated to unmeasured regions to obtain total multiplicities $\\langle \\pi^{-} \\rangle$. A new scheme to calculate the mean number of wounded nucleons $\\langle W \\rangle$ utilizing the EPOS MC model is described. Using data from other experiments, a comparison of $\\frac{\\langle \\pi \\rangle}{\\langle W \\rangle}$ for different collisions and beam momenta is discussed

  13. Efficient multi-mode to single-mode conversion in a 61 port photonic lantern

    DEFF Research Database (Denmark)

    Noordegraaf, Danny; Skovgaard, Peter M. W.; Dybendahl Maack, Martin

    2010-01-01

    We demonstrate the fabrication of a multi-mode (MM) to 61 port single-mode (SM) splitter or "Photonic Lantern". Low port count Photonic Lanterns were first described by Leon-Saval et al. (2005). These are based on a photonic crystal fiber type design, with air-holes defining the multi-mode fiber...... (MMF) cladding. Our fabricated Photonic Lanterns are solid all-glass versions, with the MMF defined by a low-index tube surrounding the single-mode fibers (SMFs). We show experimentally that these devices can be used to achieve efficient and reversible coupling between a MMF and 61 SMFs, when perfectly...... of astrophotonics for coupling MM star-light to an ensemble of SM fibers in order to perform fiber Bragg grating based spectral filtering....

  14. Deep Chandra observations of TeV binaries - I. LS I +61°303

    NARCIS (Netherlands)

    Rea, N.; Torres, D.F.; van der Klis, M.; Jonker, P.G.; Méndez, M.; Sierpowska-Bartosik, A.

    2010-01-01

    We report on a 95 ks Chandra observation of the TeV emitting high-mass X-ray binary LS I +61°303, using the ACIS-S camera in continuous clocking mode to search for a possible X-ray pulsar in this system. The observation was performed while the compact object was passing from phase 0.94 to 0.98 in

  15. Deep Chandra observations of TeV binaries - I. LSI+61°303

    NARCIS (Netherlands)

    Rea, N.; Torres, D. F.; van der Klis, M.; Jonker, P. G.; Méndez, M.; Sierpowska-Bartosik, A.

    We report on a 95ks Chandra observation of the TeV emitting high-mass X-ray binary LSI+61°303, using the ACIS-S camera in continuous clocking mode to search for a possible X-ray pulsar in this system. The observation was performed while the compact object was passing from phase 0.94 to 0.98 in its

  16. A case of well-established breastfeeding for a 61-year-old woman after menopause

    DEFF Research Database (Denmark)

    Emmersen, P.B.; Kronborg, V.H.; Illeborg, L.

    2008-01-01

    During recent years, an increasing number of women who have become pregnant after fertility treatment, including oocyte transplantation, have presented at obstetric departments. A number of these women want to breastfeed their children even though they are postmenopausal. However, whether this is...... this is possible has remained doubtful, and any possible special needs in establishing their breastfeeding are not described. The experience of establishing breastfeeding in a postmenopausal woman aged 61 years is reported Udgivelsesdato: 2008/5...

  17. Superplastic behaviour of an AZ61 alloy processed by equal channel angular extrusion

    OpenAIRE

    M. Eddahbi; Ruano, Oscar Antonio

    2006-01-01

    This study is concerned with microstructural and mechanical characterization of the superplastic behaviour of a magnesium base AZ61 alloy processed by equal channel angular extrusion (ECA). Microscopic examinations showed that the microstructure after ECA was homogeneous and the grain size was about 5 mm. The extruded material showed better mechanical properties than the rolled material. The strain rate sensitivity exponent, at 250ºC, was 0.5 at strain rates ranging from 10-4 to 5 . 10-...

  18. Defense Acquisition Research Journal. Volume 19, Number 1, Issue 61, January 2012

    Science.gov (United States)

    2012-01-01

    January 2012 Vol. 19 No. 1 ISSUE 61 p. 121 The Defense Acquisition Professional Reading List Wired for War: The Robotics Revolution and Conflict...rise of robotics surely marks the most far-reaching paradigm shift of 21st century defense acquisition. PRESENTED ON BEHALF OF DAU BY: THE DEFENSE...different export control lists. Nonetheless, U.S. space firms are expected to navigate through this maze of bureaucracy and comply with regulations. Failure

  19. Characterization of the T61 human breast carcinoma established in nude mice

    DEFF Research Database (Denmark)

    Brünner, N; Bastert, G B; Poulsen, H S

    1985-01-01

    and flow cytometric DNA analysis to be aneuploid. By electron microscopy, the tumour cells were shown to display the characteristics of glandular epithelium; a light microscopic examination revealed morphological characteristics similar to those of an axillary metastasis of the patient from whom the T61...... human breast tumours grown in nude mice, this tumour may provide a valuable supplement in the study of human breast cancer and endocrine treatment....

  20. The Effect of Metformin and GANT61 Combinations on the Radiosensitivity of Prostate Cancer Cells.

    Science.gov (United States)

    Gonnissen, Annelies; Isebaert, Sofie; McKee, Chad M; Muschel, Ruth J; Haustermans, Karin

    2017-02-13

    The anti-diabetes drug metformin has been shown to have anti-neoplastic effects in several tumor models through its effects on energy metabolism and protein synthesis. Recent studies show that metformin also targets Hedgehog (Hh) signaling, a developmental pathway re-activated in several tumor types, including prostate cancer (PCa). Furthermore, we and others have shown that Hh signaling is an important target for radiosensitization. Here, we evaluated the combination of metformin and the Hh inhibitor GANT61 (GLI-ANTagonist 61) with or without ionizing radiation in three PCa cell lines (PC3, DU145, 22Rv1). The effect on proliferation, radiosensitivity, apoptosis, cell cycle distribution, reactive oxygen species production, DNA repair, gene and protein expression was investigated. Furthermore, this treatment combination was also assessed in vivo. Metformin was shown to interact with Hh signaling by inhibiting the effector protein glioma-associated oncogene homolog 1 (GLI1) in PCa cells both in vitro and in vivo. The combination of metformin and GANT61 significantly inhibited PCa cell growth in vitro and enhanced the radiation response of 22Rv1 cells compared to either single agent. Nevertheless, neither the growth inhibitory effect nor the radiosensitization effect of the combination treatment observed in vitro was seen in vivo. Although the interaction between metformin and Hh signaling seems to be promising from a therapeutic point of view in vitro, more research is needed when implementing this combination strategy in vivo.

  1. Use of poliglecaprone 25 for perineal urethrostomy in cats: 61 cases (2007-2013).

    Science.gov (United States)

    Frem, Daniel L; Hottinger, Heidi A; Hunter, Suzanne L; Trout, Nicholas J

    2017-10-15

    OBJECTIVE To determine frequency of postoperative complications in cats undergoing perineal urethrostomy (PU) in which poliglecaprone 25 was used for closure and identify possible predisposing factors for development of complications. DESIGN Retrospective case series. ANIMALS 61 cats that underwent PU. PROCEDURES Medical records for cats that underwent PU at Gulf Coast Veterinary Specialists between 2007 and 2012 were reviewed. Information regarding signalment, perioperative conditions, surgical procedures, treatments, and postoperative complications were obtained from medical records and by telephone follow-up. RESULTS 11 of 61 (18%) cats developed minor short-term (ie, ≤ 2 months after surgery) complications, 1 of 61 (1.6%) cats developed a major short-term complication requiring surgical revision, and 16 of 38 (42%) cats developed minor long-term complications. No major long-term complications were identified. Preoperative urinary tract infection was significantly associated with development of minor short-term complications, but use of an indwelling urinary catheter after surgery was not significantly associated with development of postoperative complications. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that poliglecaprone 25 may be an acceptable suture for apposition of mucosa to skin in cats undergoing PU. Short- and long-term complication rates and percentage of cats requiring revision surgery were comparable to values reported in previous studies in which slowly absorbable or nonabsorbable sutures were used.

  2. EXCEPTIONALLY BRIGHT TEV FLARES FROM THE BINARY LS I +61° 303

    Energy Technology Data Exchange (ETDEWEB)

    Archambault, S. [Physics Department, McGill University, Montreal, QC H3A 2T8 (Canada); Archer, A.; Buckley, J. H.; Bugaev, V. [Department of Physics, Washington University, St. Louis, MO 63130 (United States); Aune, T.; Buchovecky, M. [Department of Physics and Astronomy, University of California, Los Angeles, CA 90095 (United States); Barnacka, A. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Benbow, W.; Cerruti, M. [Fred Lawrence Whipple Observatory, Harvard-Smithsonian Center for Astrophysics, Amado, AZ 85645 (United States); Bird, R.; Collins-Hughes, E. [School of Physics, University College Dublin, Belfield, Dublin 4 (Ireland); Byrum, K. [Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Cardenzana, J. V; Dickinson, H. J.; Eisch, J. D. [Department of Physics and Astronomy, Iowa State University, Ames, IA 50011 (United States); Chen, X. [Institute of Physics and Astronomy, University of Potsdam, D-14476 Potsdam-Golm (Germany); Ciupik, L. [Astronomy Department, Adler Planetarium and Astronomy Museum, Chicago, IL 60605 (United States); Connolly, M. P. [School of Physics, National University of Ireland Galway, University Road, Galway (Ireland); Cui, W. [Department of Physics and Astronomy, Purdue University, West Lafayette, IN 47907 (United States); Dumm, J., E-mail: anna.ofaolain.de.bhroithe@desy.de [School of Physics and Astronomy, University of Minnesota, Minneapolis, MN 55455 (United States); and others

    2016-01-20

    The TeV binary system LS I +61° 303 is known for its regular, non-thermal emission pattern that traces the orbital period of the compact object in its 26.5 day orbit around its B0 Ve star companion. The system typically presents elevated TeV emission around apastron passage with flux levels between 5% and 15% of the steady flux from the Crab Nebula (>300 GeV). In this article, VERITAS observations of LS I +61° 303 taken in late 2014 are presented, during which bright TeV flares around apastron at flux levels peaking above 30% of the Crab Nebula flux were detected. This is the brightest such activity from this source ever seen in the TeV regime. The strong outbursts have rise and fall times of less than a day. The short timescale of the flares, in conjunction with the observation of 10 TeV photons from LS I +61° 303 during the flares, provides constraints on the properties of the accelerator in the source.

  3. WEB based user's applications for NA61/SHINE experiment at CERN

    CERN Document Server

    Piwek, Mateusz

    1. Introduction The Master Thesis titled „Web based users applications for NA61/SHINE experiment at CERN” presents the World Wide Web technologies that has been used during development of the software suite for NA61/SHINE experiment. Presented software was implemented and is use by a group of approximately sixty users 1 . The NA61/SHINE is one of many projects that takes place in the European Organization for Nuclear Research – CERN located near Geneva. 1.1. About CERN CERN (French: Organisation européenne pour la recherche nucléaire 2 ) was established on 29 th of September 1954. Poland is a member state since 1991, however a for a long time before joining CERN Poland as the only country of Communist Block had an observatory status. Nowadays Polish scientists are taking a part in a main CERN's experiments such as ALICE, ATLAS or CMS. CERN's essential scientific facilities are the particle physics accelerators and detectors. The beam provided by the accelerator or collider by interacting w...

  4. Sleep Physiology Alterations Precede Plethoric Phenotypic Changes in R6/1 Huntington's Disease Mice.

    Directory of Open Access Journals (Sweden)

    Fanny Lebreton

    Full Text Available In hereditary neurodegenerative Huntington's disease (HD, there exists a growing consideration that sleep and circadian dysregulations may be important symptoms. It is not known, however, whether sleep abnormalities contribute to other behavioral deficits in HD patients and mouse models. To determine the precise chronology for sleep physiology alterations and other sensory, motor, psychiatric and cognitive symptoms of HD, the same R6/1 HD transgenics and their wild-type littermates were recorded monthly for sleep electroencephalogram (EEG together with a wide range of behavioral tests according to a longitudinal plan. We found an early and progressive deterioration of both sleep architecture and EEG brain rhythms in R6/1 mice, which are correlated timely with their spatial working memory impairments. Sleep fragmentation and memory impairments were accompanied by the loss of delta (1-4 Hz power in the transgenic mice, the magnitude of which increased with age and disease progression. These precocious sleep and cognitive impairments were followed by deficits in social behavior, sensory and motor abilities. Our data confirm the existence and importance of sleep physiology alterations in the widely used R6/1 mouse line and highlight their precedence over other plethoric phenotypic changes. The brainwave abnormalities, may represent a novel biomarker and point to innovative therapeutic interventions against HD.

  5. 42 CFR 61.17 - Termination on grounds other than those relating to moral character or loyalty.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Termination on grounds other than those relating to moral character or loyalty. 61.17 Section 61.17 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF... Termination on grounds other than those relating to moral character or loyalty. The Surgeon General may...

  6. File list: ALL.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

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  7. File list: ALL.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 All antigens Blood Jurkat (...e.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  8. File list: Oth.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 TFs and others Blood Jurkat...07306,SRX107307,SRX128777,SRX128782 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Bld.20.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  9. File list: ALL.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available ALL.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 All antigens Blood Jurkat (...e.biosciencedbc.jp/kyushu-u/hg19/assembled/ALL.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  10. File list: Oth.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 TFs and others Blood Jurkat...28780,SRX107307,SRX128784,SRX107306 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Bld.10.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  11. File list: Oth.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 TFs and others Blood Jurkat...28784,SRX107307,SRX128780,SRX128781 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Bld.05.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  12. File list: Oth.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available Oth.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR hg19 TFs and others Blood Jurkat...28777,SRX128782,SRX128784,SRX107307 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/assembled/Oth.Bld.50.AllAg.Jurkat_BRACKETLClone_E6-1BRACKETR.bed ...

  13. 28 CFR Appendix C to Part 61 - Immigration and Naturalization Service Procedures Relating to the Implementation of the National...

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Immigration and Naturalization Service... ENVIRONMENTAL POLICY ACT Pt. 61, App. C Appendix C to Part 61—Immigration and Naturalization Service Procedures..., construction, and maintenance of new and existing INS facilities. All activities concerning the Immigration and...

  14. 26 CFR 1.61-10 - Alimony and separate maintenance payments; annuities; income from life insurance and endowment...

    Science.gov (United States)

    2010-04-01

    ...; annuities; income from life insurance and endowment contracts. 1.61-10 Section 1.61-10 Internal Revenue... separate maintenance payments; annuities; income from life insurance and endowment contracts. (a) In general. Alimony and separate maintenance payments, annuities, and income from life insurance and...

  15. 21 CFR 212.61 - What must I do to ensure the stability of my PET drug products through expiry?

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 4 2010-04-01 2010-04-01 false What must I do to ensure the stability of my PET drug products through expiry? 212.61 Section 212.61 Food and Drugs FOOD AND DRUG ADMINISTRATION... the stability of my PET drug products through expiry? (a) Stability testing program. You must...

  16. 40 CFR 61.155 - Standard for operations that convert asbestos-containing waste material into nonasbestos...

    Science.gov (United States)

    2010-07-01

    ... clean emissions containing particulate asbestos material before they escape to, or are vented to, the... asbestos-containing waste material into nonasbestos (asbestos-free) material. 61.155 Section 61.155... for operations that convert asbestos-containing waste material into nonasbestos (asbestos-free...

  17. 49 CFR 39.61 - What requirements must PVOs meet concerning the accessibility of terminals and other landside...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What requirements must PVOs meet concerning the accessibility of terminals and other landside facilities? 39.61 Section 39.61 Transportation Office of the Secretary of Transportation TRANSPORTATION FOR INDIVIDUALS WITH DISABILITIES: PASSENGER VESSELS...

  18. 45 CFR 61.15 - How to dispute the accuracy of Healthcare Integrity and Protection Data Bank information.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false How to dispute the accuracy of Healthcare Integrity and Protection Data Bank information. 61.15 Section 61.15 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE...

  19. 45 CFR 61.9 - Reporting civil judgments related to the delivery of a health care item or service.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Reporting civil judgments related to the delivery of a health care item or service. 61.9 Section 61.9 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION HEALTHCARE INTEGRITY AND PROTECTION DATA BANK FOR FINAL ADVERSE INFORMATION ON HEALTH CARE PROVIDERS, SUPPLIERS AND...

  20. Interactions between the R2R3-MYB transcription factor, AtMYB61, and target DNA binding sites.

    Directory of Open Access Journals (Sweden)

    Michael B Prouse

    Full Text Available Despite the prominent roles played by R2R3-MYB transcription factors in the regulation of plant gene expression, little is known about the details of how these proteins interact with their DNA targets. For example, while Arabidopsis thaliana R2R3-MYB protein AtMYB61 is known to alter transcript abundance of a specific set of target genes, little is known about the specific DNA sequences to which AtMYB61 binds. To address this gap in knowledge, DNA sequences bound by AtMYB61 were identified using cyclic amplification and selection of targets (CASTing. The DNA targets identified using this approach corresponded to AC elements, sequences enriched in adenosine and cytosine nucleotides. The preferred target sequence that bound with the greatest affinity to AtMYB61 recombinant protein was ACCTAC, the AC-I element. Mutational analyses based on the AC-I element showed that ACC nucleotides in the AC-I element served as the core recognition motif, critical for AtMYB61 binding. Molecular modelling predicted interactions between AtMYB61 amino acid residues and corresponding nucleotides in the DNA targets. The affinity between AtMYB61 and specific target DNA sequences did not correlate with AtMYB61-driven transcriptional activation with each of the target sequences. CASTing-selected motifs were found in the regulatory regions of genes previously shown to be regulated by AtMYB61. Taken together, these findings are consistent with the hypothesis that AtMYB61 regulates transcription from specific cis-acting AC elements in vivo. The results shed light on the specifics of DNA binding by an important family of plant-specific transcriptional regulators.