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Sample records for scandium 57

  1. Lifetime measurements and oscillator strengths in singly ionized scandium and the solar abundance of scandium

    Science.gov (United States)

    Pehlivan Rhodin, A.; Belmonte, M. T.; Engström, L.; Lundberg, H.; Nilsson, H.; Hartman, H.; Pickering, J. C.; Clear, C.; Quinet, P.; Fivet, V.; Palmeri, P.

    2017-12-01

    The lifetimes of 17 even-parity levels (3d5s, 3d4d, 3d6s and 4p2) in the region 57 743-77 837 cm-1 of singly ionized scandium (Sc II) were measured by two-step time-resolved laser induced fluorescence spectroscopy. Oscillator strengths of 57 lines from these highly excited upper levels were derived using a hollow cathode discharge lamp and a Fourier transform spectrometer. In addition, Hartree-Fock calculations where both the main relativistic and core-polarization effects were taken into account were carried out for both low- and high-excitation levels. There is a good agreement for most of the lines between our calculated branching fractions and the measurements of Lawler & Dakin in the region 9000-45 000 cm-1 for low excitation levels and with our measurements for high excitation levels in the region 23 500-63 100 cm-1. This, in turn, allowed us to combine the calculated branching fractions with the available experimental lifetimes to determine semi-empirical oscillator strengths for a set of 380 E1 transitions in Sc II. These oscillator strengths include the weak lines that were used previously to derive the solar abundance of scandium. The solar abundance of scandium is now estimated to logε⊙ = 3.04 ± 0.13 using these semi-empirical oscillator strengths to shift the values determined by Scott et al. The new estimated abundance value is in agreement with the meteoritic value (logεmet = 3.05 ± 0.02) of Lodders, Palme & Gail.

  2. Scandium recovery from slags after oxidized nickel ore processing

    Science.gov (United States)

    Smyshlyaev, Denis; Botalov, Maxim; Bunkov, Grigory; Rychkov, Vladimir; Kirillov, Evgeny; Kirillov, Sergey; Semenishchev, Vladimir

    2017-09-01

    One of the possible sources of scandium production - waste (slags) from processing of oxidized nickel ores, has been considered in present research work. The hydrometallurgical method has been selected as the primary for scandium extraction. Different reagents for leaching of scandium, such as sulfuric acid, various carbonate salts and fluorides, have been tested. Sulfuric acid has been recognized as an optimal leaching reagent. Sulfuric acid concentration of 100 g L-1 allowed recovering up to 97 % of scandium.

  3. Influence of scandium concentration on power generation figure of merit of scandium aluminum nitride thin films

    Energy Technology Data Exchange (ETDEWEB)

    Akiyama, Morito; Nagase, Toshimi [Measurement Solution Research Center, National Institute of Advanced Industrials Science and Technology, Tosu, Saga 841-0052 (Japan); Umeda, Keiichi; Honda, Atsushi [Murata Manufacturing Co., Ltd., Nagaokakyo, Kyoto 617-8555 (Japan)

    2013-01-14

    The authors have investigated the influence of scandium concentration on the power generation figure of merit (FOM) of scandium aluminum nitride (Sc{sub x}Al{sub 1-x}N) films prepared by cosputtering. The power generation FOM strongly depends on the scandium concentration. The FOM of Sc{sub 0.41}Al{sub 0.59}N film was 67 GPa, indicating that the FOM is five times larger than that of AlN. The FOM of Sc{sub 0.41}Al{sub 0.59}N film is higher than those of lead zirconate titanate and Pb(Mg{sub 1/3}Nb{sub 2/3})O{sub 3}-PbTiO{sub 3} films, which is the highest reported for any piezoelectric thin films. The high FOM of Sc{sub 0.41}Al{sub 0.59}N film is due to the high d{sub 31} and the low relative permittivity.

  4. Smelting of Scandium by Microwave Irradiation.

    Science.gov (United States)

    Fujii, Satoshi; Tsubaki, Shuntaro; Inazu, Naomi; Suzuki, Eiichi; Wada, Yuji

    2017-09-27

    Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices-including acoustic ones-because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF₃ through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  5. Smelting of Scandium by Microwave Irradiation

    Directory of Open Access Journals (Sweden)

    Satoshi Fujii

    2017-09-01

    Full Text Available Scandium is being explored as an alloying element for aluminum alloys, which are gaining importance as high-performance lightweight structural alloys in the transportation industry. A few years ago, Sc was also found to be suitable for use in electrical devices. High-Sc-content ScAlN thin films have attracted significant attention because of their strong piezoelectricity. The piezoelectric response of ScAlN suggests that ScAlN thin films formed on a hard substrate would be suitable surface acoustic wave wideband filters for next-generation wireless communication systems. However, it is often difficult to use ScAlN thin films in MEMS devices—including acoustic ones—because of the extremely high price of metallic Sc, given the difficulty associated with smelting it. Here, we propose a novel process for smelting Sc metal by microwave irradiation. Sc metal was able to be obtained successfully from ScF3 through a microwave-irradiation-based carbon reduction reaction. The reaction temperature for this reduction process was approximately 880°C, which is half of that for the conventional smelting process involving reduction with Ca. Thus, the proposed microwave irradiation process has significant potential for use in the smelting of Sc metal.

  6. Hydrometallurgical methods of recovery of scandium from the wastes of various technologies

    Science.gov (United States)

    Molchanova, T. V.; Akimova, I. D.; Smirnov, K. M.; Krylova, O. K.; Zharova, E. V.

    2017-03-01

    The recovery of scandium from the wastes of the production of uranium, titanium, iron-vanadium, and alumina is studied. The applied acid schemes of scandium transfer to a solution followed by ion-exchange recovery and extraction concentration of scandium ensure the precipitation of crude scandium oxides containing up to 5% Sc2O3. Scandium oxides of 99.96-99.99% purity are formed after additional refining of these crude oxides according to an extraction technology using a mixture 15% multiradical phosphine oxide or Cyanex-925 + 15% tributyl phosphate in kerosene.

  7. Synthesis and Reactivity of a Scandium Terminal Hydride: H2  Activation by a Scandium Terminal Imido Complex.

    Science.gov (United States)

    Han, Xianghao; Xiang, Li; Lamsfus, Carlos A; Mao, Weiqing; Lu, Erli; Maron, Laurent; Leng, Xuebing; Chen, Yaofeng

    2017-10-20

    Dihydrogen is easily activated by a scandium terminal imido complex containing the weakly coordinated THF. The reaction proceeds through a 1,2-addition mechanism, which is distinct from the σ-bond metathesis mechanism reported to date for rare-earth metal-mediated H2 activation. This reaction yields a scandium terminal hydride, which is structurally well-characterized, being the first one to date. The reactivity of this hydride is reported with unsaturated substrates, further shedding light on the existence of the terminal hydride complex. Interestingly, the H2 activation can be reversible. DFT investigations further eludciate the mechanistic aspects of the reactivity of the scandium anilido-terminal hydride complex with PhNCS but also on the reversible H2 activation process. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Thermoelectric material comprising scandium doped zinc cadmium oxide

    DEFF Research Database (Denmark)

    2016-01-01

    There is presented a composition of scandium doped Zinc Cadmium Oxide with the general formula ZnzCdxScyO which the inventors have prepared, and for which material the inventors have made the insight that it is particularly advantageous as an n-type oxide material, such as particularly advantageous...

  9. Scandium/carbon filters for soft x rays

    NARCIS (Netherlands)

    Artioukov, IA; Kasyanov, YS; Kopylets, IA; Pershin, YP; Romanova, SA

    2003-01-01

    This Note deals with thin-film soft x-ray filters for operation at the wavelengths near carbon K edge (similar to4.5 nm). The filters were fabricated by magnetron sputtering deposition of thin layers of scandium (total thickness 0.1-0.2 mum) onto films of polypropylene (thickness 1.5 mum) and

  10. Solvent extraction of scandium from lateritic nickel- cobalt ores using different organic reagents

    OpenAIRE

    Ferizoğlu Ece; Kaya Şerif; Topkaya Yavuz A.

    2016-01-01

    Scandium is the most important and strategic metal that can be recovered as a by-product from lateritic nickel-cobalt ores. In this research, different extractants were investigated in order to extract scandium from a sulfate medium by a using a solvent extraction method. Generally, the organic extractants are classified as acidic, neutral and basic organophosphorus compounds. However, in solvent extraction of scandium, the acidic and neutral organophosphorus compounds are preferred due to th...

  11. BASIC RESEARCH ON THE SEPARATION OF SCANDIUM YTTRIUM, AND THE RARE EARTHS BY SOLVENT EXTRACTION.

    Science.gov (United States)

    RARE EARTH ELEMENTS, * SOLVENT EXTRACTION ), (*CHELATE COMPOUNDS, RARE EARTH ELEMENTS), PURIFICATION, ATOMIC SPECTROSCOPY, SCANDIUM, YTTRIUM, PRASEODYMIUM, SAMARIUM, EUROPIUM, GADOLINIUM, TERBIUM, FLUORINE COMPOUNDS, KETONES

  12. Determination of scandium concentrate composition by WD-XRF and ICP-MS methods

    Science.gov (United States)

    Sarkisova, A. S.; Shibitko, A. O.; Abramov, A. V.; Rebrin, O. I.; Bunkov, G. M.; Lisienko, D. G.

    2017-09-01

    WD-XRF spectroscopy was applied for determining composition of scandium concentrate (ScC) containing 70 % scandium fluoride. Determination of ScC composition was performed using 6 glass beads reference materials produced by fusing synthesized mixture of analyte compounds with the lithium-borate flux in the ratio of 1:10. ScC powder with the known composition was then used as a powder pellet reference material to analyze scandium concentrate from technological line by external standard method. ICP-MS method was employed to control the ScC composition. The statistical data processing and metrological parameters evaluation of the analytical technique developed were carried out.

  13. Tin etching from metallic and oxidized scandium thin films

    Science.gov (United States)

    Pachecka, M.; Lee, C. J.; Sturm, J. M.; Bijkerk, F.

    2017-08-01

    The role of oxide on Sn adhesion to Sc surfaces was studied with in-situ ellipsometry, X-ray photoelectron spectroscopy and secondary electron microscopy. Sn etching with hydrogen radicals was performed on metallic Sc, metallic Sc with a native oxide, and a fully oxidized Sc layer. The results show that Sn adsorbs rather weakly to a non-oxidized Sc surface, and is etched relatively easily by atomic hydrogen. In contrast, the presence of native oxide on Sc allows Sn to adsorb more strongly to the surface, slowing the etching. Furthermore, thinner layers of scandium oxide result in weaker Sn adsorption, indicating that the layer beneath the oxide plays a significant role in determining the adsorption strength. Unexpectedly, for Sn on Sc2O3, and, to a lesser extent, for Sn on Sc, the etch rate shows a variation over time, which is explained by surface restructuring, temperature change, and hydrogen adsorption saturation.

  14. Tin etching from metallic and oxidized scandium thin films

    Directory of Open Access Journals (Sweden)

    M. Pachecka

    2017-08-01

    Full Text Available The role of oxide on Sn adhesion to Sc surfaces was studied with in-situ ellipsometry, X-ray photoelectron spectroscopy and secondary electron microscopy. Sn etching with hydrogen radicals was performed on metallic Sc, metallic Sc with a native oxide, and a fully oxidized Sc layer. The results show that Sn adsorbs rather weakly to a non-oxidized Sc surface, and is etched relatively easily by atomic hydrogen. In contrast, the presence of native oxide on Sc allows Sn to adsorb more strongly to the surface, slowing the etching. Furthermore, thinner layers of scandium oxide result in weaker Sn adsorption, indicating that the layer beneath the oxide plays a significant role in determining the adsorption strength. Unexpectedly, for Sn on Sc2O3, and, to a lesser extent, for Sn on Sc, the etch rate shows a variation over time, which is explained by surface restructuring, temperature change, and hydrogen adsorption saturation.

  15. Extraction of scandium by liquid di-2-ethylhexylphosphoric acid in fusible diluents

    Directory of Open Access Journals (Sweden)

    Ainur Isatayeva

    2015-03-01

    Full Text Available Currently widespread distribution of extraction methods using fusible reagents can be explained by a number of advantages, such as high kinetic characteristics of the process, the ease separation of two phases, high selectivity of many extractants, relatively complete regeneration. For the extraction of scandium in technological order, neutral and cation exchange extractants can be used. Several extraction reagents melt easily at high temperatures, and such melts can be used for extraction. Efficiency of the extraction of metal by cation reagents depends on many factors. Extraction of scandium by melt mixtures of di-2-ethylhexylphosphoric acid - higher carboxylic acid - paraffin and the effect of acidity of the aqueous phase, the concentration of scandium and the aqueous extractant in the organic phase, the volume ratio of organic and aqueous phases on the extraction of metal were studied. It was found that the extraction of scandium proceeds through the cation exchange mechanism. Scandium was extracted quantitatively (> 99.0% from acid solutions. The optimal concentration of di-2-ethylhexylphosphoric acid in the extractant was 0,250 M, quantitative extraction of scandium was observed in the range of its concentrations of 10-3-10-6 M and the volume ratio of organic phases to aqueous phases of 1:5 - 1:20.

  16. Thermodynamic and kinetic study of scandium(III) complexes of DTPA and DOTA: a step toward scandium radiopharmaceuticals.

    Science.gov (United States)

    Pniok, Miroslav; Kubíček, Vojtěch; Havlíčková, Jana; Kotek, Jan; Sabatie-Gogová, Andrea; Plutnar, Jan; Huclier-Markai, Sandrine; Hermann, Petr

    2014-06-23

    Diethylenetriamine-N,N,N',N'',N''-pentaacetic acid (DTPA) and 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) scandium(III) complexes were investigated in the solution and solid state. Three (45)Sc NMR spectroscopic references suitable for aqueous solutions were suggested: 0.1 M Sc(ClO4)3 in 1 M aq. HClO4 (δSc =0.0 ppm), 0.1 M ScCl3 in 1 M aq. HCl (δSc =1.75 ppm) and 0.01 M [Sc(ox)4](5-) (ox(2-) = oxalato) in 1 M aq. K2C2O4 (δSc =8.31 ppm). In solution, [Sc(dtpa)](2-) complex (δSc = 83 ppm, Δν = 770 Hz) has a rather symmetric ligand field unlike highly unsymmetrical donor atom arrangement in [Sc(dota)](-) anion (δSc = 100 ppm, Δν = 4300 Hz). The solid-state structure of K8[Sc2(ox)7]⋅13 H2O contains two [Sc(ox)3](3-) units bridged by twice "side-on" coordinated oxalate anion with Sc(3+) ion in a dodecahedral O8 arrangement. Structures of [Sc(dtpa)](2-) and [Sc(dota)](-) in [(Hguanidine)]2[Sc(dtpa)]⋅3 H2O and K[Sc(dota)][H6 dota]Cl2⋅4 H2O, respectively, are analogous to those of trivalent lanthanide complexes with the same ligands. The [Sc(dota)](-) unit exhibits twisted square-antiprismatic arrangement without an axial ligand (TSA' isomer) and [Sc(dota)](-) and (H6 dota)(2+) units are bridged by a K(+) cation. A surprisingly high value of the last DOTA dissociation constant (pKa =12.9) was determined by potentiometry and confirmed by using NMR spectroscopy. Stability constants of scandium(III) complexes (log KScL 27.43 and 30.79 for DTPA and DOTA, respectively) were determined from potentiometric and (45)Sc NMR spectroscopic data. Both complexes are fully formed even below pH 2. Complexation of DOTA with the Sc(3+) ion is much faster than with trivalent lanthanides. Proton-assisted decomplexation of the [Sc(dota)](-) complex (τ1/2 =45 h; 1 M aq. HCl, 25 °C) is much slower than that for [Ln(dota)](-) complexes. Therefore, DOTA and its derivatives seem to be very suitable ligands for scandium

  17. Effects of iron on intermetallic compound formation in scandium modified Al–Si–Mg Alloys

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [National Metal and Materials Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@mail.kmutt.ac.th [Production Engineering Department, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2014-12-15

    Highlights: • Iron reduces the modification effects of scandium in Al–Si–Mg alloys. • Morphologies of Sc-rich intermetallic phases vary with Fe and Sc contents and the cooling rates. • Sc neutralizes effects of Fe by changing Fe-rich intermetallic phases from platelets to more cubic. - Abstract: In general, iron has a strong tendency to dissolve in molten aluminum. Iron has very low solid solubility in aluminum–silicon casting alloys, so it will form intermetallic compounds that cause detrimental effects on mechanical properties. In this work, the effects of iron on intermetallic compound formations in scandium modified Al–Si–Mg alloys were studied. There were two levels of iron addition (0.2 and 0.4 wt.%) and two levels of scandium addition (0.2 and 0.4 wt.%). We found that the effects of scandium modification decreased with increasing iron addition. The morphologies of the complex intermetallic compounds were characterized by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and electron backscatter diffraction (EBSD) techniques. It was found that scandium changes the morphology of Fe-rich intermetallic compounds from β-phase (plate-like) to α-phase, which reduces the harmful effects of β-phase.

  18. Solvent extraction of scandium from lateritic nickel- cobalt ores using different organic reagents

    Directory of Open Access Journals (Sweden)

    Ferizoğlu Ece

    2016-01-01

    Full Text Available Scandium is the most important and strategic metal that can be recovered as a by-product from lateritic nickel-cobalt ores. In this research, different extractants were investigated in order to extract scandium from a sulfate medium by a using a solvent extraction method. Generally, the organic extractants are classified as acidic, neutral and basic organophosphorus compounds. However, in solvent extraction of scandium, the acidic and neutral organophosphorus compounds are preferred due to their higher extraction efficiencies. Thus, the aim of the present study was to compare the scandium extraction efficiencies of some acidic and neutral organic reagents. For this reason, Ionquest 290 (Bis(2,4,4-trimethylpenthyl phosphonic acid, DEHPA (Di(2-ethylhexyl phosphoric acid, Cyanex 272 ((Bis(2,4,4-trimethylpentyl phosphinic acid which are acidic organophosphorus compounds, and Cyanex 923 (Trialkylphosphine oxide, which is a neutral organophosphorus compound, were used. The extraction capacities of these organics were studied with respect to the extractant concentration at same pH and phase ratio. As a result of the study, DEHPA was found to have higher scandium extraction efficiency with lower iron extraction at pH = 0.55 at a phase ratio of 10:1 = A:O.

  19. Correlation between stoichiometry and properties of scandium oxide films prepared by reactive magnetron sputtering

    Science.gov (United States)

    Belosludtsev, Alexandr; Juškevičius, Kęstutis; Ceizaris, Lukas; Samuilovas, Romanas; Stanionytė, Sandra; Jasulaitienė, Vitalija; Kičas, Simonas

    2018-01-01

    Scandium oxide films were deposited on fused silica substrates by reactive pulsed DC magnetron sputtering. The use of feed-back optical emission monitoring enabled high-rate reactive deposition of films with tunable stoichiometry and properties. The under-stoichiometric, stoichiometric and over-stoichiometric scandium oxide films were prepared. The compressive stress in films was between 235 and 530 MPa. We showed that phase structure, density, surface roughness and optical properties of the scandium oxide are affected by the film stoichiometry and deposition conditions. Transparent scandium oxide films were slightly hydrophobic (94 ± 3°), homogeneous with a crystallite size of 20 ± 5 nm. The lowest extinction coefficient 0.7 × 10-3, the highest refractive index 2.08 (both quantities at the wavelength of 355 nm) and the highest density 4.1 ± 0.1 g cm-3 exhibited film prepared with the stoichiometric composition. Stoichiometric scandium oxide can be used in various optical applications as high refractive index and wide bandgap material. Transitions to under- or over-stoichiometry lead to a decrease of film density, refractive index and increase of the extinction coefficient.

  20. Mossbauer investigation of scandium oxide-hematite nanoparticles

    Science.gov (United States)

    Allwes, Mark; Sorescu, Monica

    Scandium oxide-doped hematite, xSc2O3*(1-x)alpha-Fe2O3 with molar concentration x =0.1, 0.3, and 0.5 was prepared by using ball milling, taking samples at times 0, 2, 4, 8, and 12 hours. The resulting Mossbauer spectra of the nanoparticles systems were parameterized using NORMOS-90. For each concentration, the spectra at 0 hours only consisted of 1 sextet, as the substitution of Sc2O3into Fe2O3 did not appear until after 2 hours of ball milling time (BMT). Concentration x =0.1 at BMT 2hours consisted of 2 sextets while x =0.3 and 0.5 were fit with 1 sextet and 1 quadrupole-split doublet. Concentration x =0.1 at BMT 4 and 8 hours consisted of 3 sextets, and at BMT 12 hours consisted of 4 sextets. For concentrations x =0.3 and 0.5 at BMT 4, 8, and 12 hours the spectra were fit with 3 sextets and 1 quadrupole-split doublet. With increasing initial concentration, the appearance of the quadrupole-split doublet became more pronounced, indicating the substitution of Fe into Sc2O3 occurred. But for x =0.1, the BMT did influence the number of sextets needed, causing an increase in substitution of Sc2O3 into Fe2O3.

  1. Association between toenail scandium levels and risk of acute myocardial infarction in European men: The EURAMIC and Heavy Metals Study

    NARCIS (Netherlands)

    Gómez-Aracena, J.; Martin-Moreno, J.M.; Riemersma, R.A.; Bode, P.; Gutiérrez-Bedmar, M.; Gorgojo, L.; Kark, J.D.; Garcia-Rodríguez, A.; Gomez-Gracia, E.; Kardinaal, A.F.M.; Aro, A.; Veer, P. van 't; Wedel, H.; Kok, F.J.; Fernández-Crehuet, J.

    2002-01-01

    The association between scandium status and risk of acute myocardial infarction (MI) was examined in a multicentre case control study in 10 centres from Europe and Israel. Scandium in toenails was assessed in 684 cases and 724 controls less than 70 years of age. Mean concentrations of toenail

  2. In-source laser spectroscopy developments at TRILIS-towards spectroscopy on actinium and scandium

    Energy Technology Data Exchange (ETDEWEB)

    Raeder, Sebastian, E-mail: raeder@triumf.ca; Dombsky, Marik; Heggen, Henning; Lassen, Jens; Quenzel, Thomas [TRIUMF, Canada' s National Laboratory for Nuclear and Particle Physics (Canada); Sjoedin, Marica [GANIL (France); Teigelhoefer, Andrea [TRIUMF, Canada' s National Laboratory for Nuclear and Particle Physics (Canada); Wendt, Klaus [Johannes Gutenberg-Universitaet Mainz, Institut fuer Physik (Germany)

    2013-04-15

    Resonance Ionization Laser Ion Sources (RILIS) have become a versatile tool for production and study of exotic nuclides at Isotope Separator On-Line (ISOL) facilities such as ISAC at TRIUMF. The recent development and addition of a grating tuned spectroscopy laser to the TRIUMF RILIS solid state laser system allows for wide range spectral scans to investigate atomic structures on short lived isotopes, e.g., those from the element actinium, produced in uranium targets at ISAC. In addition, development of new and improved laser ionization schemes for rare isotope production at ISAC is ongoing. Here spectroscopic studies on bound states, Rydberg states and autoionizing (AI) resonances on scandium using the existing off-line capabilities are reported. These results allowed to identify a suitable ionization scheme for scandium via excitation into an autoionizing state at 58,104 cm{sup - 1} which has subsequently been used for ionization of on-line produced exotic scandium isotopes.

  3. Process and Mechanical Properties: Applicability of a Scandium modified Al-alloy for Laser Additive Manufacturing

    Science.gov (United States)

    Schmidtke, K.; Palm, F.; Hawkins, A.; Emmelmann, C.

    The applicability of an aluminium alloy containing scandium for laser additive manufacturing (LAM) is considered. Modified aluminium alloys with a scandium content beyond the eutectic point offer great potential to become a high prioritized aerospace material. Depending on other alloying elements like magnesium or zirconium, strongly required weight reduction, corrosion resistance and improved strength properties of metallic light weight alloys can be achieved. The development, production and testing of parts built up by a laser powder bed process will be presented with regard to the qualification of the new material concept "ScalmalloyRP®" for laser additive manufacturing.

  4. Synthesis and structural characterization of scandium SALEN complexes.

    Science.gov (United States)

    Meermann, Christian; Sirsch, Peter; Törnroos, Karl W; Anwander, Reiner

    2006-02-28

    A series of heteroleptic scandium SALEN complexes, [(SALEN)Sc(mu-Cl)]2 and (SALEN)Sc[N(SiHMe2)2] is obtained via amine elimination reactions using [Sc(N(i)Pr2)2(mu-Cl)(THF)]2 and Sc[N(SiHMe2)2]3(THF) as metal precursors, respectively. H(2)SALEN ligand precursors comprising H2Salen [(1,2-ethandiyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol], H2Salpren [(2,2-dimethylpropanediyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol], H2Salcyc [(1R,2R)-(-)-1,2-cyclohexanediyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol] and H2Salphen [((1S,2S)-(-)-1,2-diphenylethandiyl)bis(nitrilomethylidyne)bis(2,4-di-tert-butyl)phenol] are selected according to solubility and ligand backbone variation ("=N-(R)-N=" bite angle) criteria. Consideration is given to the feasibility of [Cl --> NR2] and [N(SiHMe2)2--> OSiR3] secondary ligand exchange reactions. X-ray crystal structure analyses of donor-free (Salpren)Sc(N(i)Pr2), (R,R)-(Salcyc)Sc[N(SiHMe2)2], (Salen)Sc(OSi(t)BuPh2) and (Salphen)Sc(OSiH(t)Bu2) reveal (i) a very short Sc-N bond distance of 2.000(3) A, (ii) weak beta(Si-H)(amido)-Sc agostic interactions and (iii) an exclusive intramolecularly tetradentate and intrinsically bent coordination mode of the SALEN ligands with angle(Ph,Ph) dihedral angles and Sc-[N(2)O(2)] distances in the 124.27(9)-127.7(3) degrees and 0.638(1)-0.688(1) A range, respectively.

  5. Scandium SALEN complexes bearing chloro, aryloxo, and hydroxo ligands.

    Science.gov (United States)

    Meermann, Christian; Törnroos, Karl W; Anwander, Reiner

    2009-03-16

    Heteroleptic amide complexes (SALEN)Sc[N(SiHMe(2))(2)] (SALEN = Salen(tBu,tBu), Salcyc(tBu,tBu), or Salpren(tBu,tBu) if not stated differently) were examined as synthesis precursors according to silylamine elimination reactions. Treatment of (SALEN)Sc[N(SiHMe(2))(2)] with H(2)O or phenols (HOAr(R,R); R = tBu, iPr) afforded complexes [(SALEN)Sc(mu-OH)](2) and (SALEN)Sc(OAr(R,R)), while chloro exchange products were formed from the respective reactions with NH(4)Cl or AlMe(2)Cl. Such complexes [(SALEN)Sc(mu-Cl)](2) and (SALEN)ScCl(thf) were also obtained by utilizing alternative synthesis protocols, allowing for controlled donor absence and presence. Heteroleptic amide precursors [Sc(NiPr(2))(2)(mu-Cl)(thf)](2) and [Sc[N(SiHMe(2))(2)](2)(mu-Cl)(thf)](2) readily undergo amine elimination reactions with H(2)SALEN derivatives to form the corresponding chloride complexes. Spectroscopic and X-ray structural data of the heteroleptic scandium complexes revealed an exclusive intramolecular tetradentate coordination mode of the SALEN ligands independent of the SALEN ligand bite angle and the nature of the "second" ligand (chloro, amido, aryloxo, hydroxo). The coordination of the SALEN ligands is rationalized on the basis of (a) the displacement d of the metal center from the [N(2)O(2)] least-squares plane, (b) the dihedral angle alpha between the phenyl rings of the salicylidene moieties, and (c) the angle beta = Ct-Ln-Ct (Ct = centroid of the phenyl rings) in the case of strongly twisted ligands.

  6. Vertical distribution of scandium in the north central Pacific

    Science.gov (United States)

    Amakawa, Hiroshi; Nomura, Miho; Sasaki, Kazunori; Oura, Yasuji; Ebihara, Mitsuru

    2007-06-01

    The concentrations of scandium (Sc) in seawater, which have remained unreported since the early 1970s, were determined together with those of yttrium (Y) and lanthanides (Ln) with samples from the north central Pacific Ocean (St. BO-3). The Sc concentration shows a so-called nutrient-like profile: it increases gradually from the surface (about 2 pmol/kg) to the ocean floor (about 20 pmol/kg). That pattern closely resembles those of Y and Ln (correlation coefficient (r) > 0.92). Some light-to-middle Ln (Pr-Tb) exhibit a closer correlation with Sc than do Y, La, or heavy Ln (Ho-Lu). In contrast, Y/Sc and Ln/Sc ratios (elemental abundance ratios) indicate that Sc is depleted compared to either Y or Ln in seawater more than in loess, which represents chemical compositions of crustal material. These observations offer a conflicting view of chemical reactivity related Y, Ln, and Sc: r values show that the chemical reactivity of Sc resembles those of Y and Ln, but differences of Y/Sc and Ln/Sc ratios in seawater and in loess suggest that the chemical reactivity of Sc differs from those of Y and Ln. More Sc data for seawater are necessary to clarify the chemical reactivity of Sc in the ocean. We also propose that comparative studies of vertical profiles of Sc and such elements as Fe, Ti, Zr, and Hf showing so-called nutrient-like profiles at the same oceanic stations would be helpful and effective for clarifying the behavior of Sc in the ocean.

  7. In situ observation of the reaction of scandium and carbon by neutron diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Juarez-Arellano, Erick A., E-mail: eajuarez@unpa.edu.m [Institut fuer Geowissenschaften, Universitaet Frankfurt, Altenhoeferallee 1, 60438 Frankfurt a.M. (Germany); Universidad del Papaloapan, Circuito Central 200, Parque Industrial, Tuxtepec 68301 (Mexico); Winkler, Bjorn [Institut fuer Geowissenschaften, Universitaet Frankfurt, Altenhoeferallee 1, 60438 Frankfurt a.M. (Germany); Vogel, Sven C. [Los Alamos National Laboratory, Lujan Center. Mail Stop H805, Los Alamos, NM 87545 (United States); Senyshyn, Anatoliy [Forschungsneutronenquelle Heinz Maier-Leibnitz (FRM II), Technische Universitaet Muenchen, Lichtenbergstr. 1, D-85747 Garching (Germany); Materialwissenschaft, TU Darmstadt, Petersensstr. 23, D-64287 Darmstadt (Germany); Kammler, Daniel R. [Sandia National Laboratories, Albuquerque, NM 87185 (United States); Avalos-Borja, Miguel [CNyN, UNAM, A. Postal 2681, Ensenada, B.C. (Mexico)

    2011-01-05

    Research highlights: {yields} Exist two ScC cubic phases with B1-structure type differing in site occupancy of C. {yields} A new orthorhombic scandium carbide phase is formed at 1473(50) K. {yields} The recrystallization of alpha-Sc occurs between 1000 and 1223 K. - Abstract: The formation of scandium carbides by reaction of the elements has been investigated by in situ neutron diffraction up to 1823 K. On heating, the recrystallization of {alpha}-Sc occurs between 1000 and 1223 K. The formation of Sc{sub 2}C and ScC (NaCl-B1 type structure) phases has been detected at 1323 and 1373 K, respectively. The formation of a new orthorhombic scandium carbide phase was observed at 1473(50) K. Once the scandium carbides are formed they are stable upon heating or cooling. No other phases were detected in the present study, in which the system was always carbon saturated. The thermal expansion coefficients of all phases have been determined, they are constant throughout the temperature interval studied.

  8. The effects of aluminum or scandium on the toughness, density and ...

    African Journals Online (AJOL)

    The effects of the substitution of aluminum or scandium on the density, toughness as well as the stability of the phases formed by such an addition on platinum, iridium, rhodium and palladium metals were evaluated with the density functional quantum mechanical calculation methods. All the metals had four atoms per ...

  9. Effects of erbium‑and chromium‑doped yttrium scandium gallium ...

    African Journals Online (AJOL)

    2014-08-21

    Aug 21, 2014 ... surfaces because of its high power, and the ablation was deeper for these samples. High‑magnification SEM ... Key words: Erbium chromium‑doped yttrium scandium gallium garnet, diode laser, restorative dental materials, scanning electron ... garnet (Nd: YAG) and carbon dioxide (CO2) lasers on indirect ...

  10. Chemical and biological evaluation of scandium(III)-polyaminopolycarboxylate complexes as potential PET agents and radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Huclier-Markai, S.; Sabatie, A.; Ribet, S. [Univ. de Nantes (France). Lab. Subatech; Kubicek, V.; Hermann, P. [Charles Univ., Prague (Czech Republic). Dept. of Inorganic Chemistry; Paris, M. [Univ. de Nantes (France). Inst. des Materiaux; Vidaud, C. [CEA/DSV/iBEB/SBTN, Bagnols sur Ceze (France). Lab. d' Etude des Proteines Cibles; Cutler, C.S. [Univ. of Missouri, Columbia, MO (United States). Reserach Reactor Center

    2011-07-01

    Scandium isotopes ({sup 44}Sc, {sup 47}Sc) are more available and their properties are convenient for either PET imaging or radiotherapy. To use them in nuclear medicine, ligands forming complexes with a high stability are necessary. Available experimental data on stability constants for complexes of ligands such as EDTA, DTPA, DOTA, NOTA and TETA with various metal ions have been published. But scandium is the exception since scarce data is available in the literature. Values of stability constants of Sc(III) with the ligands were determined by free-ion selective radiotracer extraction, complemented by {sup 45}Sc NMR and potentiometry data. The thermodynamic stability of the Sc-complexes increases in the order TETA < NOTA < EDTA < DTPA < DOTA. The in vitro stability of the Sc(III) complexes was studied in the presence of hydroxyapatite and rat serum to estimate their in vivo stability. The most stable complex was shown to be Sc-DOTA.

  11. Precipitation behaviour and recrystallisation resistance in aluminum alloys with additions of hafnium, scandium and zirconium

    OpenAIRE

    Hallem, Håkon

    2005-01-01

    The overall objective of this work has been to develop aluminium alloys, which after hot and cold deformation are able to withstand high temperatures without recrystallising. This has been done by investigating aluminium alloys with various additions of hafnium, scandium and zirconium, with a main focus on Hf and to which extent it may partly substitute or replace Zr and/or Sc as a dispersoid forming elements in these alloys. What is the effect of hafnium, alone and in combination with Zr...

  12. Pilot-scale recovery of rare earths and scandium from phosphogypsum and uranium leachates

    Directory of Open Access Journals (Sweden)

    Mashkovtsev Maxim

    2016-01-01

    Full Text Available Ural Federal University (UrFU and VTT have performed joint research on development of industrial technologies for the extraction of REM and Scandium compounds from phosphogypsum and Uranium ISL leachate solutions. Leaching-absorption experiments at UrFU have been supported with multicomponent solution modelling by VTT. The simulations have been performed with VTT’s ChemSheet/Balas program and can be used for speciation calculations in the lixiviant solution. The experimental work combines solvent extraction with advanced ion exchange methodology in a pilot facility capable of treating 5 m3 solution per hour. Currently, the plant produces cerium carbonate, lanthanum oxide, neodymium oxide and concentrate of heavy rare earth metals. A batch of 45 t solids has been processed with the gain of 100 kg’s of REM concentrate. A mini-pilot plant with productivity above 50 liters per hour has been applied to recover scandium oxide and REE concentrates from the uranium ISL solution. As the preliminary product contains radioactivity (mainly strontium, an additional decontamination and cleaning of both concentrates by extraction has rendered a necessity. Finally a purified 99% concentrate of scandium oxide as well as 99% rare earth concentrate are received.

  13. Optimization of scandium oxide growth by high pressure sputtering on silicon

    Energy Technology Data Exchange (ETDEWEB)

    Feijoo, P.C., E-mail: pedronska@fis.ucm.es; Pampillon, M.A.; San Andres, E.; Lucia, M.L.

    2012-12-30

    This work demonstrates the viability of scandium oxide deposition on silicon by means of high pressure sputtering. Deposition pressure and radio frequency power are varied for optimization of the properties of the thin films and the ScO{sub x}/Si interface. The physical characterization was performed by ellipsometry, Fourier transform infrared spectroscopy, x-ray diffraction and transmission electron microscopy. Aluminum gate electrodes were evaporated for metal-insulator-semiconductor (MIS) fabrication. From the electrical characterization of the MIS devices, the density of interfacial defects is found to decrease with deposition pressure, showing a reduced plasma damage of the substrate surface for higher pressures. This is also supported by lower flatband voltage shifts in the capacitance versus voltage hysteresis curves. Sputtering at high pressures (above 100 Pa) reduces the interfacial SiO{sub x} formation, according to the infrared spectra. The growth rates decrease with deposition pressure, so a very accurate control of the layer thicknesses could be provided. - Highlights: Black-Right-Pointing-Pointer Scandium oxide is considered as a high permittivity dielectric. Black-Right-Pointing-Pointer Scandium oxide was deposited on Si by high pressure sputtering. Black-Right-Pointing-Pointer Characterization was performed for deposition condition optimization. Black-Right-Pointing-Pointer High deposition pressures showed higher film and interface quality.

  14. Recovery of Scandium from Leachate of Sulfation-Roasted Bayer Red Mud by Liquid-Liquid Extraction

    Science.gov (United States)

    Liu, Zhaobo; Li, Hongxu; Jing, Qiankun; Zhang, Mingming

    2017-11-01

    The leachate obtained from sulfation-roasted Bayer red mud is suitable for extraction of scandium by liquid-liquid solvent extraction because it contains trace amounts of Fe3+ and Si4+. In this study, a completely new metallurgical process for selective recovery of scandium from Bayer red mud was proposed. The extraction performances of Sc3+, Fe3+, Al3+, Si4+, Ca2+, and Na+ from synthetic leachate of sulfation-roasted red mud were first investigated using organophosphorus extractants (di-2-ethylhexyl phosphoric acid P204 and 2-ethylhexyl phosphoric acid mono-2-ethylhexyl ester P507) and carboxylic acid extractant (Versatic acid 10). It shows that P204 has an excellent extraction ability and that it can be applied to the scandium recovery. P507 and Versatic acid 10 are much poorer in performance for selective extraction of scandium. In the leachate of sulfation-roasted red mud, approximately 97% scandium can be recovered using a P204/sulfonated kerosene (1% v/v) extraction system under the condition of an organic-to-aqueous phase ratio of 10:1 and with an extraction temperature of 15°C.

  15. Scandium-doped zinc cadmium oxide as a new stable n-type oxide thermoelectric material

    DEFF Research Database (Denmark)

    Han, Li; Christensen, Dennis Valbjørn; Bhowmik, Arghya

    2016-01-01

    Scandium-doped zinc cadmium oxide (Sc-doped ZnCdO) is proposed as a new n-type oxide thermoelectric material. The material is sintered in air to maintain the oxygen stoichiometry and avoid instability issues. The successful alloying of CdO with ZnO at a molar ratio of 1 : 9 significantly reduced...... is a good candidate for improving the overall conversion efficiencies in oxide thermoelectric modules. Meanwhile, Sc-doped ZnCdO is robust in air at high temperatures, whereas other n-type materials, such as Al-doped ZnO, will experience rapid degradation of their electrical conductivity and ZT....

  16. Scandium and yttrium phosphasalen complexes as initiators for ring-opening polymerization of cyclic esters.

    Science.gov (United States)

    Bakewell, Clare; White, Andrew J P; Long, Nicholas J; Williams, Charlotte K

    2015-03-02

    The synthesis and characterization of novel scandium and yttrium phosphasalen complexes is reported, where phosphasalen refers to two different bis(iminophosphorane) derivatives of the more ubiquitous salen ligands. The activity of the complexes as initiators for the ring-opening polymerization of cyclic esters is presented. The scandium complexes are inactive for lactide polymerization but slow and controlled initiators for ε-caprolactone polymerization. The lack of activity toward lactide exhibited by these compounds is probed, and a rare example of single-monomer insertion product, unable to undergo further reactions with lactide, is identified. In contrast, the analogous yttrium phosphasalen complex is a very active initiator for the ring-opening polymerization of rac-lactide (kobs = 1.5 × 10(-3) s(-1) at 1:500 [yttrium initiator]:[rac-lactide], 1 M overall concentration of lactide in THF at 298 K). In addition to being a very fast initiator, the yttrium complex also maintains excellent levels of polymerization control and a high degree of isoselectivity, with the probability of isotactic enchainment being Pi = 0.78 at 298 K.

  17. Thermodynamic parameters of scandium trifluoride and triiodide in the condensed state

    Science.gov (United States)

    Aristova, N. M.; Belov, G. V.

    2015-06-01

    The thermodynamic properties of new classes of compounds, particularly scandium trihalides ScF3, ScCl3, ScBr3, and ScI3, are added to the IVTANTHERMO software package. A critical analysis and processing of the entire array of primary data available in the literature is performed. An equation approximating the temperature dependence of heat capacity in the temperature range 298.15- T m (K) is derived for each crystalline scandium trihalide. The resulting equations C {/p po}( T) for the solid state and the data for the liquid phase are used to calculate the thermodynamic functions of entropy, the reduced Gibbs free energies, and the enthalpy increments. Both the experimental data available in literature and the missing estimated thermodynamic data are used in calculations. The error of the recommended values is estimated in all cases. In the first part of this work, we describe the thermodynamic properties of ScF3 and ScI3 used as the reference data for calculating the thermodynamic functions of ScCl3 and ScBr3, for which experimental data are either very scarce or missing altogether. The resulting data are added to the database of the IVTANTHERMO software package.

  18. Recovery of Scandium(III) from Aqueous Solutions by Solvent Extraction with the Functionalized Ionic Liquid Betainium Bis(trifluoromethylsulfonyl)imide

    OpenAIRE

    Onghena, Bieke; Binnemans, Koen

    2015-01-01

    The ionic liquid betainium is(trifluoromethylsulfonyl)imide [Hbet][Tf2N] was used for the extraction of scandium from aqueous solutions. The influence of several extraction parameters on the extraction efficiency was investigated, including the initial metal concentration, phase ratio, and pH. The extraction kinetics was examined, and a comparison was made between conventional liquid−liquid extraction and homogeneous liquid−liquid extraction (HLLE). The stoichiometry of the extracted scandium...

  19. Modification mechanism of eutectic silicon in Al–6Si–0.3Mg alloy with scandium

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [Manufacturing and Systems Engineering Program, Department of Production Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand); Kajornchaiyakul, Julathep [National Metal and Material Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@kmutt.ac.th [Manufacturing and Systems Engineering Program, Department of Production Engineering, Faculty of Engineering, King Mongkut’s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2013-10-25

    Highlights: •Morphologies and growth of Sc and Sr-modified eutectic silicon resemble those of dendrites. •Crystal orientation of eutectic aluminum depends on growth characteristics of eutectic silicon. •We report strong evidence of the occurrence of an impurity-induced twinning mechanism. -- Abstract: The modification mechanism of eutectic silicon in Al–6Si–0.3Mg alloy with scandium was studied. The crystallographic orientation relationships between primary dendrites and the eutectic phase of unmodified and modified Al–6Si–0.3 Mg alloys were determined using electron backscatter diffraction (EBSD). The orientation of aluminum modified with scandium in the eutectic phase was different from that of the neighboring primary dendrites. This result implies that eutectic aluminum grows epitaxially from the surrounding primary aluminum dendrites in the unmodified alloy and that eutectic aluminum grows competitively from the surrounding primary aluminum dendrites in the modified alloy. The pole figure maps of eutectic Si in the [1 0 0], [1 1 0] and [1 1 1] axes of the unmodified and Sc-modified alloys were different, suggesting that the eutectic Al and Si crystals in modified alloy growth are more isotropic and cover a larger set of directions. The lattice fringes of Si of the alloys with and without Sc modification were different in the TEM results. The lattice fringes of Si in modified alloy were found to be multiple twins. However, this was not observed in the unmodified alloy. The growth characteristic of eutectic Si crystal in modified alloy suggests the occurrence of multiple twinning reactions and the formation of a high density of twins. This modification mechanism by Sc is explained by the results of scanning electron microscopy (SEM), electron backscatter diffraction (EBSD) and transmission electron microscopy (TEM) analysis, which provide strong evidence of the occurrence of the impurity-induced twinning (IIT) mechanism.

  20. Grain refinement mechanism in an Al-Si-Mg alloy with scandium

    Energy Technology Data Exchange (ETDEWEB)

    Patakham, Ussadawut [Department of Production Engineering, Faculty of Engineering, King Mongkut' s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand); Kajornchaiyakul, Julathep [National Metal and Material Technology Center, National Science and Technology Development Agency, 114 Thailand Science Park, Klong Nueng, Klong Luang, Pathumthani 12120 (Thailand); Limmaneevichitr, Chaowalit, E-mail: chaowalit.lim@kmutt.ac.th [Department of Production Engineering, Faculty of Engineering, King Mongkut' s University of Technology Thonburi, 126 Pracha-Utid Rd., Bangmod, Tungkhru, Bangkok 10140 (Thailand)

    2012-11-25

    Highlights: Black-Right-Pointing-Pointer Scandium can be used to refine aluminum grains in an Al-Si-Mg aluminum alloy. Black-Right-Pointing-Pointer The effectiveness of Sc is lower than that of conventional Al-Ti grain refiners. Black-Right-Pointing-Pointer Al{sub 3}Sc particles can act as heterogeneous nuclei of aluminum phases. Black-Right-Pointing-Pointer Higher alloying elements cause more intermetallic compound phases. Black-Right-Pointing-Pointer Those phases cannot effectively act as heterogeneous nuclei compared with Al{sub 3}Sc particles. - Abstract: Grain refinement of the primary aluminum ({alpha}-Al) phase in a hypoeutectic Al-Si alloy using scandium (Sc) was studied to identify the grain refinement mechanism. Optical microscopy (OM), Scanning electron microscopy (SEM) with energy dispersive spectroscopy (EDS) and electron backscatter diffraction (EBSD) techniques were extensively used in this study. We found that Sc refined grains of primary aluminum. However, the grain refinement efficiency of Sc was considerably lower than that of titanium (Ti) in the Al-Si-Mg foundry alloy. It was evident that the precipitated Sc-containing phases acted as heterogeneous nucleation sites for the primary aluminum phase. The Sc-containing heterogeneous sites are irregular in shape with sizes between 3 and 5 {mu}m. At least three groups of nuclei based on their chemical composition were found, i.e., (i) Al and Sc, (ii) Al, Si, Mg, and Sc, and (iii) Al, Si, Mg, Sc, and Fe. Crystal orientation mapping showed primary aluminum dendrites with one orientation in each grain near Al{sub 3}Sc particles. The grain refinement mechanism of Sc for aluminum relies on heterogeneous nucleation of Al{sub 3}Sc particles, with less responsibly for grain growth restriction. Many intermetallic phases with Al, Si, Fe, Mg and Sc as their major components were found, and these phases could not effectively act as heterogeneous nuclei.

  1. Neutron and Charged-Particle Induced Cross Sections for Radiochemistry for Isotopes of Scandium, Titanium, Vanadium, Chromium, Manganese, and Iron

    Energy Technology Data Exchange (ETDEWEB)

    Kelley, K; Hoffman, R D; Dietrich, F S; Bauer, R; Mustafa, M

    2004-11-30

    We have developed a set of modeled nuclear reaction cross sections for use in radiochemical diagnostics. Local systematics for the input parameters required by the Hauser-Feshbach statistical model were developed and used to calculate neutron and proton induced nuclear reaction cross sections in the mass region of scandium, titanium, vanadium, chromium, manganese, and iron (21 {le} Z {le} 26, 20 {le} N {le} 32).

  2. A composite cathode based on scandium doped titanate with enhanced electrocatalytic activity towards direct carbon dioxide electrolysis.

    Science.gov (United States)

    Yang, Liming; Xie, Kui; Wu, Lan; Qin, Qingqing; Zhang, Jun; Zhang, Yong; Xie, Ting; Wu, Yucheng

    2014-10-21

    A composite cathode based on redox-stable La0.2Sr0.8TiO(3+δ) (LSTO) can perform direct carbon dioxide electrolysis; however, the insufficient electro-catalytic activity limits the electrode performances and current efficiencies. In this work, catalytically active scandium is doped into LSTO to enhance the electro-catalytic activity for CO2 electrolysis. The structures, electronic conductivities and ionic conductivities of La0.2Sr0.8Ti(1-x)Sc(x)O (LSTS(x)O) (x = 0, 0.05, 0.1, 0.15 and 0.2) are systematically studied and further correlated with electrode performances. The ionic conductivities of single-phase LSTS(x)O (x = 0, 0.05, 0.1 and 0.15) remarkably improve versus the scandium doping contents though the electrical conductivities gradually change in an adverse trend. Electrochemical measurements demonstrate promising electrode polarisation of LSTS(x)O electrodes and increasing scandium doping contents accordingly improve electrode performances. The Faradic efficiencies of carbon dioxide electrolysis are enhanced by 20% with LSTS0.15O in contrast to bare LSTO electrodes in a solid oxide electrolyser at 800 °C.

  3. Adsorption of hydrogen in Scandium/Titanium decorated nitrogen doped carbon nanotube

    Energy Technology Data Exchange (ETDEWEB)

    Mananghaya, Michael, E-mail: mikemananghaya@gmail.com [De La Salle University, 2401 Taft Ave, 0922, Manila (Philippines); DLSU STC Laguna Boulevard, LTI Spine Road Barangays Biñan and Malamig, Biñan City, Laguna (Philippines); DOST-ASTHRDP, PCIEERD, Gen. Santos Ave., Bicutan, Taguig City 1631 (Philippines); Belo, Lawrence Phoa; Beltran, Arnel [De La Salle University, 2401 Taft Ave, 0922, Manila (Philippines); DLSU STC Laguna Boulevard, LTI Spine Road Barangays Biñan and Malamig, Biñan City, Laguna (Philippines)

    2016-09-01

    Nitrogen doped Carbon Nanotube with divacancy (4ND-CN{sub x}NT) that is decorated with Scandium and Titanium as potential hydrogen storage medium using the pseudo potential density functional method was investigated. Highly localized states near the Fermi level, which are derived from the nitrogen defects, contribute to strong Sc and Ti bindings, which prevent metal aggregation and improve the material stability. A detailed Comparison of the Hydrogen adsorption capability with promising system-weight efficiency of Sc over Ti was elucidated when functionalized with 4ND-CN{sub x}NT. Finally, the (Sc/4ND){sub 10}-CN{sub x}CNT composite material has a thermodynamically favorable adsorption and consecutive adsorption energy for ideal reversible adsorption and desorption of hydrogen at room temperature such that it can hold at least 5.8 wt% hydrogen molecules at the LDA and GGA level. - Highlights: • Carbon Nanotube with divacancy (4ND-CN{sub x}NT) decorated with Sc and Ti. • Nitrogen defects, contribute to strong Sc and Ti bindings. • H{sub 2} and (Sc/4ND){sub 10}-CN{sub x}CNT has a favorable adsorption. • 5.8 wt% adsorption at the LDA and GGA level.

  4. Urinary monitoring of exposure to yttrium, scandium, and europium in male Wistar rats.

    Science.gov (United States)

    Kitamura, Yasuhiro; Usuda, Kan; Shimizu, Hiroyasu; Fujimoto, Keiichi; Kono, Rei; Fujita, Aiko; Kono, Koichi

    2012-12-01

    On the assumption that rare earth elements (REEs) are nontoxic, they are being utilized as replacements of toxic heavy metals in novel technological applications. However, REEs are not entirely innocuous, and their impact on health is still uncertain. In the past decade, our laboratory has studied the urinary excretion of REEs in male Wistar rats given chlorides of europium, scandium, and yttrium solutions by one-shot intraperitoneal injection or oral dose. The present paper describes three experiments for the suitability and appropriateness of a method to use urine for biological monitoring of exposure to these REEs. The concentrations of REEs were determined in cumulative urine samples taken at 0-24 h by inductively coupled plasma atomic emission spectroscopy, showing that the urinary excretion of REEs is <2 %. Rare earth elements form colloidal conjugates in the bloodstream, which make high REEs accumulation in the reticuloendothelial system and glomeruli and low urinary excretion. The high sensitivity of inductively coupled plasma-argon emission spectrometry analytical methods, with detection limits of <2 μg/L, makes urine a comprehensive assessment tool that reflects REE exposure. The analytical method and animal experimental model described in this study will be of great importance and encourage further discussion for future studies.

  5. Selective recovery of vanadium and scandium by ion exchange with D201 and solvent extraction using P507 from hydrochloric acid leaching solution of red mud.

    Science.gov (United States)

    Zhu, Xiaobo; Li, Wang; Tang, Sen; Zeng, Majian; Bai, Pengyuan; Chen, Lunjian

    2017-05-01

    D201 resin and P507 extractant diluted with sulfonated kerosene were used to respectively separate vanadium and scandium, and impurity ions from hydrochloric acid leaching solution of red mud. More than 99% of vanadium was selectively adsorbed from the hydrochloric acid leaching solution under the conditions of pH value of 1.8, volume ratio of leaching solution to resin of 10, and flow rate of 3.33 mL/min. Maximum extraction and separation of scandium was observed from the acid leaching solution at an aqueous pH value of 0.2. More than 99% of scandium can be selectively extracted using 15% P507, 5% TBP at the aqueous solution/organic phase (A/O) ratio of 10:1 for 6 min. The loaded organic phase was washed with 0.3 mol/L sulfuric acid, wherein most impurities were removed. After the process of desorption or stripping, precipitation, and roasting, high-purity V2O5 and Sc2O3 were obtained. Finally, a conceptual flow sheet was established to separate and recover vanadium and scandium from red mud hydrochloric acid leaching solution. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Random-field Potts model for the polar domains of lead magnesium niobate and lead scandium tantalate

    Energy Technology Data Exchange (ETDEWEB)

    Qian, H.; Bursill, L.A

    1997-06-01

    A random filed Potts model is used to establish the spatial relationship between the nanoscale distribution of charges chemical defects and nanoscale polar domains for the perovskite-based relaxor materials lead magnesium niobate (PMN) and lead scandium tantalate (PST). The random fields are not set stochastically but are determined initially by the distribution of B-site cations (Mg, Nb) or (Sc, Ta) generated by Monte Carlo NNNI-model simulations for the chemical defects. An appropriate random field Potts model is derived and algorithms developed for a 2D lattice. It is shown that the local fields are strongly correlated with the chemical domain walls and that polar domains as a function of decreasing temperature is simulated for the two cases of PMN and PST. The dynamics of the polar clusters is also discussed. 33 refs., 9 figs.

  7. Development of methods for the selective separation of scandium, zirconium and tin for radiopharmaceutical applications; Entwicklung von Methoden zur selektiven Trennung von Scandium, Zirkonium und Zinn fuer radiopharmazeutische Anwendungen

    Energy Technology Data Exchange (ETDEWEB)

    Dirks-Fandrei, Carina

    2014-07-01

    The subject of the present work is the development of fast and highly selective methods for the separation and purification of scandium, zirconium and tin radionuclides from potential target materials for use in nuclear medicine. A number of selected resins (TrisKem International) were first characterized with respect to their extraction behaviour towards a large number of cations. Characterization studies were performed in batch experiments by determination of weight distribution ratios D{sub w} and further the influence of interferences on the uptake of these elements was evaluated. Weight distribution ratios were determined in different acids and acid concentrations with main focus on scandium, tin or zirconium. The interference of macro amounts of Calcium and Ti on the Sc extraction was evaluated as well as the interference of macro amounts of Y on the Zr extraction. Best suited uptake conditions were found for Scandium on DGA were determined to be 2.5 M HNO{sub 3} for Ti-Targets and 0.1 M HNO{sub 3} for Calcium-Targets. Otherwise it is also possible to extract Sc with TRU Resin. High uptakes were obtained at 2.5 M HNO{sub 3} for simulated Ti- and Calcium-targets. Separation methods were developed using elution studies; employed conditions were chosen according to parameters evaluated in the batch-experiment. The developed methods allowed separating Sc very rapidly in high purity very rapidly from Ti- or Calcium-targets. For Zr a separation method based on UTEVA Resin has been developed. Following results of batch experiments simulated Y-target solution were loaded onto a UTEVA resin column from 6 M HNO{sub 3}; the elution of Zr could be performed in 0.01 M oxalic acid. Decontamination factors in the order of 10{sup 4}-10{sup 5} could be obtained applying the developed method; the method thus allowed separating Zr in a high purity. Initial testing of a method for the separation of Sn from Cd targets based on the use of TBP Resin showed that the TBP resin seems

  8. The impact of an erbium, chromium:yttrium-scandium-gallium-garnet laser with radial-firing tips on endodontic treatment.

    Science.gov (United States)

    Schoop, U; Barylyak, A; Goharkhay, K; Beer, F; Wernisch, J; Georgopoulos, A; Sperr, W; Moritz, A

    2009-01-01

    Radial-firing tips should allow a more homogeneous laser irradiation of root canal walls. The aim of the study was to assess the effects of erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser irradiation in conjunction with those newly designed tips. The investigation comprised bacteriology, morphological evaluations and temperature measurements. Root canals were inoculated with two test strains and laser irradiated with power settings of 0.6 W and 0.9 W and a repetition rate of 20 Hz. Subsequently, the samples were subjected to microbiological evaluation. The morphological changes of the canal walls were assessed by scanning electron microscopy. To reveal possible thermal side effects, we carried out temperature measurements. The bacteriological evaluation revealed a decisive disinfectant effect. Scanning electron microscopy showed the homogeneous removal of smear layer from the root canal walls. The temperature rise at the root surface during the irradiation was moderate, yielding 1.3 degrees C for the 0.6 W setting and 1.6 degrees C for the 0.9 W setting. The investigations indicated that the Er,Cr:YSGG laser, in conjunction with radial-firing tips, is a suitable tool for the elimination of bacteria in root canals and for the removal of smear layer.

  9. Effect of scandium addition on the microstructure, mechanical and wear properties of the spray formed hypereutectic aluminum–silicon alloys

    Energy Technology Data Exchange (ETDEWEB)

    Raghukiran, Nadimpalli; Kumar, Ravi, E-mail: nvrk@iitm.ac.in

    2015-08-12

    Hypereutectic Al–x%Si–0.8Sc alloys (x=13, 16, 19 and 22 wt%) were produced by spray forming. The microstructures of all the alloys exhibited very fine silicon phase with average size of about 5–10 µm irrespective of the silicon content of the alloy. Transmission electron microscopy revealed the presence of a nano-scale scandium rich phase, identified as AlSi{sub 2}Sc{sub 2} (V-phase) uniformly distributed in the alloy. The presence of V-phase resulted in higher matrix hardness (1.34 GPa) in contrast to 1.04 GPa observed in the case of binary Al–Si alloys by nanoindentation. Isothermal heat treatment at 375 °C revealed insignificant coarsening of silicon phase in both binary and ternary alloys. The Al–x%Si–0.8Sc alloys exhibited higher flow stress and tensile strength in contrast to their binary alloy counterparts which was attributed to the bi-modal size distribution of the strengthening phases in the form of nano-scale V-phase and sub-micron to 10 µm size silicon particles. The pin-on-disk wear tests exhibited appreciable improvement in the wear performance of the relatively low-silicon content ternary alloys over their binary counterparts while the high-silicon content binary and ternary alloys exhibited no much difference in the wear performance.

  10. Scandium and Titanium Containing Single-Walled Carbon Nanotubes for Hydrogen Storage: a Thermodynamic and First Principle Calculation.

    Science.gov (United States)

    Mananghaya, Michael; Yu, Dennis; Santos, Gil Nonato; Rodulfo, Emmanuel

    2016-06-15

    The generalized gradient approximation (GGA) to density functional theory (DFT) calculations indicate that the highly localized states derived from the defects of nitrogen doped carbon nanotube with divacancy (4ND-CNxNT) contribute to strong Sc and Ti bindings, which prevent metal aggregation. Comparison of the H2 adsorption capability of Sc over Ti-decorated 4ND-CNxNT shows that Ti cannot be used for reversible H2 storage due to its inherent high adsorption energy. The Sc/4ND-CNxNT possesses favorable adsorption and consecutive adsorption energy at the local-density approximation (LDA) and GGA level. Molecular dynamics (MD) study confirmed that the interaction between molecular hydrogen and 4ND-CNxNT decorated with scandium is indeed favorable. Simulations indicate that the total amount of adsorption is directly related to the operating temperature and pressure. The number of absorbed hydrogen molecules almost logarithmically increases as the pressure increases at a given temperature. The total excess adsorption of hydrogen on the (Sc/4ND)10-CNxNT arrays at 300 K is within the range set by the department of energy (DOE) with a value of at least 5.85 wt%.

  11. Ressenyes del Caplletra 57

    Directory of Open Access Journals (Sweden)

    Caplletra 57

    2014-10-01

    Full Text Available Ressenyes del Caplletra 57 (Tardor, 2014: Lluís Cabré: Bernat Metge, ‘The Dream’ of Bernat Metge / Del Somni d’en Bernat Metge, translated into English by Antonio Cortijo Ocaña and Elisabeth Lagresa, with an introduction and notes by Antonio Cortijo Ocaña, Amsterdam/Philadelphia, John Benjamins, 2013, 193 pp. Josep Soler-Carbonell: Àngels Massip-Bonet & Albert Bastardas-Boada (eds., Complexity Perspectives on Language, Communication and Society, Berlín/Heidelberg, Springer-Verlag, 2013, 255 pp. Núria Silleras Fernández: Germà Colón Domènech (ed., Els escriptors valencians del segle XV, Castelló de la Plana, Universitat Jaume I, Servei de Comunicació i Publicacions, 2013, 257 pp. Josep Martines i Peres / Jordi M. Antolí Martínez: Pere Navarro Gómez, El parlar de Cambrils, Cambrils/Valls, Ajuntament de Cambrils / Cossetània, 2012, 520 pp. Josep Daniel Climent: Santi Vallés Casanoves, Acció Valenciana (1930-1931. La consciència desvetlada, València, Acadèmia Valenciana de la Llengua, 2008, 474 pp. Josep Martines i Peres / Jordi M. Antolí Martínez Andreu Bosch i Rodoreda, El lèxic alguerès de l’agricultura i la ramaderia entre els segles XVII i XVIII, Barcelona, Institut d’Estudis Catalans, 2012, 290 pp. Joan Ferrer: Antoni Ferrando Francés, Sant Vicent Ferrer en la historiografia, la literatura, l’hagiografia i l’espiritualitat al segle XV, València, Institució Alfons el Magnànim, 2013, 225 pp. Josep Besa Camprubí: Pilar Alonso, A multi-dimensional approach to discourse coherence: from standard­ness to creativity, Berna, Peter Lang, 2014, 247 pp. Pere Císcar: Jordi Marrugat, Aspectes de la poesia catalana de la modernitat, Publicacions de l’Abadia de Montserrat, Barcelona, 2013, 558 pp. Jordi Sánchez Martí: Albert Lloret, Printing Ausiàs March: Material Culture and Renaissance Poetics, Madrid, Centro para la Edición de los Clásicos Españoles / Servicio de Publicaciones de la Universidad de

  12. Effects of scandium addition on iron-bearing phases and tensile properties of Al–7Si–0.6Mg alloys

    Energy Technology Data Exchange (ETDEWEB)

    Tzeng, Yu-Chih [Department of Mechanical Engineering, National Central University, Jhongli, Taiwan (China); Wu, Chih-Ting [Department of Vehicle Engineering, Army Academy R.O.C., Jhongli, Taiwan (China); Bor, Hui-Yun; Horng, Jain-Long; Tsai, Mu-Lin [Department of Mechanical Engineering, National Central University, Jhongli, Taiwan (China); Institute of Materials Science and Engineering, National Central University, Jhongli, Taiwan (China); Lee, Sheng-Long, E-mail: shenglon@cc.ncu.edu.tw [Department of Mechanical Engineering, National Central University, Jhongli, Taiwan (China); Institute of Materials Science and Engineering, National Central University, Jhongli, Taiwan (China)

    2014-01-21

    Iron is the most deleterious impurity in aluminum alloys and can easily combine with aluminum to form an acicular β-Al{sub 5}FeSi phase that reduces ductility during the solidification of the molten metal. Adding scandium (Sc) to Al–7Si–0.6Mg alloys can transform the acicular β-Al{sub 5}FeSi phase into a comparatively harmless nodular Sc–Fe phase (Al{sub 12}Si{sub 6}Fe{sub 2}(Mg,Sc){sub 5}). This Sc–Fe phase has a lower hardness and elastic modulus than the β-Al{sub 5}FeSi phase; it is thus less likely to initiate cracks in the Al matrix. Moreover, the nodular Sc–Fe phase can improve the fluidity of Al during solidification, reducing interdendritic shrinkage. Tensile testing measurements showed that the elongation of Al–7Si–0.6Mg alloys with 0.04 and 0.12 wt% Sc can be respectively increased by 115% and 110% compared to Al–7Si–0.6Mg without Sc. The corresponding quality indices are increased by 17% and 19%, respectively, suggesting that the tensile properties of Al–7Si–0.6Mg alloys can be enhanced by adding scandium.

  13. Separation of (44)Ti from proton irradiated scandium by using solid-phase extraction chromatography and design of (44)Ti/(44)Sc generator system.

    Science.gov (United States)

    Radchenko, V; Meyer, C A L; Engle, J W; Naranjo, C M; Unc, G A; Mastren, T; Brugh, M; Birnbaum, E R; John, K D; Nortier, F M; Fassbender, M E

    2016-12-16

    Scandium-44g (half-life 3.97h [1]) shows promise for positron emission tomography (PET) imaging of longer biological processes than that of the current gold standard, (18)F, due to its favorable decay parameters. One source of (44g)Sc is the long-lived parent nuclide (44)Ti (half-life 60.0 a). A (44)Ti/(44g)Sc generator would have the ability to provide radionuclidically pure (44g)Sc on a daily basis. The production of (44)Ti via the (45)Sc(p,2n) reaction requires high proton beam currents and long irradiation times. Recovery and purification of no-carrier added (nca) (44)Ti from scandium metal targets involves complex separation chemistry. In this study, separation systems based on solid phase extraction chromatography were investigated, including branched diglycolamide (BDGA) resin and hydroxamate based ZR resin. Results indicate that ZR resin in HCl media represents an effective (44)Ti/(44g)Sc separation system. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. 46 CFR 54.25-8 - Radiography (modifies UW-11(a), UCS-57, UNF-57, UHA-33, and UHT-57).

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Radiography (modifies UW-11(a), UCS-57, UNF-57, UHA-33, and UHT-57). 54.25-8 Section 54.25-8 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... Radiography (modifies UW-11(a), UCS-57, UNF-57, UHA-33, and UHT-57). (a) Full radiography is required for all...

  15. Gd-Sc-based mixed-metal nitride cluster fullerenes: mutual influence of the cage and cluster size and the role of scandium in the electronic structure.

    Science.gov (United States)

    Svitova, Anna L; Popov, Alexey A; Dunsch, Lothar

    2013-03-18

    The influence of the cage as well as of the cluster size has been studied in Gd-Sc nitride cluster fullerenes, which have been synthesized and isolated for these studies. A series of carbon cages ranging from C78 to C88 have been synthesized, isolated, and characterized in detail using absorption and vibrational spectroscopy as well as electrochemistry and density functional theory calculations. Gd-Sc mixed-metal cluster fullerenes in carbon cages different from C80 were described for the first time. A review of their structures, properties, and stability is given. The synthesis was performed with melamine as an effective solid source of nitrogen, providing high fullerene yield and suppressing empty fullerene formation. Substitution of gadolinium by scandium imposes a noticeable influence on the electronic structure of nitride cluster fullerenes as revealed by electrochemical, spectroscopic, and computational methods.

  16. Copper scandium zirconium phosphate

    DEFF Research Database (Denmark)

    Bond, Andrew David; Warner, Terence Edwin

    2013-01-01

    components. The [Sc(III)Zr(IV)(PO(4))(3)](2-) framework is composed of corner-sharing Sc/ZrO(6) octahedra and PO(4) tetrahedra. The Sc and Zr atoms are disordered on one atomic site on a crystallographic threefold axis. The P atom of the phosphate group lies on a crystallographic twofold axis. Nonframework...

  17. Synthesis and characterization of reduced scandium halide containing one- and two-dimensional metal bonded arrays. [Sc--ScCl3; Cs3Sc2Cl9; CsScCl3

    Energy Technology Data Exchange (ETDEWEB)

    Poeppelmeier, K.R.

    1978-08-01

    The stabilization effect of metal-metal bond formation on reduced scandium compounds was studied. The binary compounds Sc/sub 7/Cl/sub 12/, Sc/sub 5/Cl/sub 8/, Sc/sub 7/Cl/sub 10/ and ScCl were prepared by high temperature techniques and were characterized by single crystal x-ray diffraction. The respective metal arrays in these compounds can be viewed as fragments of scandium metal ranging from discrete six atom metal cluster species (Sc(Sc/sub 6/Cl/sub 12/)), through intermediate single and double infinite chain configurations ((ScCl/sub 2/)(Sc/sub 4/Cl/sub 6/)) and ((ScCl/sub 2/)(Sc/sub 6/Cl/sub 8/)) to double metal close-packed sheets (ScCl). The halogen atoms effectively isolate the clusters, chains and sheets by bonding face, edge or exo positions on the metal arrays. The common occurrence of isolated scandium (III) ions emphasizes that a minimum number of bonding electrons is required to stabilize what are formally anionic metal arrays. The distribution of the reduction electrons in these anisotropic materials was studied by magnetic susceptibility, EPR and uv-X photoelectron spectroscopy. The ternary compounds studied were Cs/sub 3/Sc/sub 2/Cl/sub 9/ and CsScCl/sub 3/. The anion-bridged metal chain of the hexagonal perovskite structure was found to stabilize scandium (II). CsScCl/sub 3/ was found to be grossly nonstoichiometric on the transition metal site and the effects of the mixed valence character were studied between the single valence extremes Cs/sub 3/Sc/sub 2 + x/Cl/sub 9/; 0< x < 1.0.

  18. Scandium functionalized carbon aerogel: Synthesis of nanoparticles and structure of a new ScOCl and properties of NaAlH{sub 4} as a function of pore size

    Energy Technology Data Exchange (ETDEWEB)

    Javadian, Payam; Nielsen, Thomas K. [Center for Energy Materials, Interdisciplinary Nanoscience Center (iNANO), and Department of Chemistry, Aarhus University, DK-8000 Aarhus (Denmark); Ravnsbæk, Dorthe B. [Department of Material Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge 02142, MA (United States); Jepsen, Lars H. [Center for Energy Materials, Interdisciplinary Nanoscience Center (iNANO), and Department of Chemistry, Aarhus University, DK-8000 Aarhus (Denmark); Polanski, Marek [Faculty of Advanced Technology and Chemistry, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw (Poland); Plocinski, Tomasz [Faculty of Material Science and Engineering, Warsaw University of Technology, 144 Woloska Str., 02-507 Warsaw (Poland); Kunce, Izabela [Faculty of Advanced Technology and Chemistry, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw (Poland); Besenbacher, Flemming [Interdisciplinary Nanoscience Center (iNANO) and Department of Physics and Astronomy, Aarhus University, DK-8000 Aarhus C (Denmark); Bystrzycki, Jerzy [Faculty of Advanced Technology and Chemistry, Military University of Technology, 2 Kaliskiego Str., 00-908 Warsaw (Poland); Jensen, Torben R., E-mail: trj@chem.au.dk [Center for Energy Materials, Interdisciplinary Nanoscience Center (iNANO), and Department of Chemistry, Aarhus University, DK-8000 Aarhus (Denmark)

    2015-11-15

    A new method for scandium-functionalization of carbon aerogels forming nanoparticles of a new scandiumoxochloride, ScOCl is presented. Sodium aluminiumhydride, NaAlH{sub 4}, is successfully melt infiltrated into the nano porous scaffolds with pore sizes of D{sub max}=7, 10, 13, 21, 26 and 39 nm, containing scandium based nano particles (<2.9 wt%) confirmed by elemental analysis and scanning electron microscopy. A systematic study of hydrogen storage properties of the nano composite materials is presented. An aqueous solution of ScCl{sub 3} was initially infiltrated and formed nanoconfined [Sc(OH)(H{sub 2}O){sub 5}]{sub 2}Cl{sub 4}(H{sub 2}O){sub 2}, which transforms to nanoparticles of a new scandium oxochloride, ScOCl at 192 °C and to Sc{sub 2}O{sub 3} at 420 °C. ScOCl crystallizes in an orthorhombic unit cell a=3.4409(8), b=3.9613(6) and c=8.178(2) Å, space group Pmmn, and is built from layers of [ScO{sub 4}Cl{sub 2}] octahedra forming neutral ScOCl layers. Temperature programmed desorption mass spectroscopy shows slightly improved kinetics for release of hydrogen with decreasing pore size. Continuous cycling of hydrogen release and uptake measured by the Sieverts' method reveal a larger preserved hydrogen storage capacity for scandium-functionalized aerogel with the larger pores (39 nm). - Highlights: • New synthesis approach for nanoporous Sc-functionalization carbon aerogel (Sc-CA). • The new scandium oxochloride, ScOCl, structure is obtained. • NaAlH{sub 4} nanoconfined in Sc-CA with pores ranging between 7 nm

  19. The use of the erbium, chromium:yttrium-scandium-gallium-garnet laser in endodontic treatment: the results of an in vitro study.

    Science.gov (United States)

    Schoop, Ulrich; Goharkhay, Kawe; Klimscha, Johannes; Zagler, Manuela; Wernisch, Johann; Georgopoulos, Apostolos; Sperr, Wolfgang; Moritz, Andreas

    2007-07-01

    The use of the erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser has become accepted in the field of cavity preparation. The development of miniaturized and flexible fiber tips has allowed this device to be used in endodontics. The authors conducted an in vitro study to assess the effects of Er,Cr:YSGG laser irradiation on root canals. The authors inoculated root canals with two bacteria, laser irradiated them at two power settings and subjected them to a quantitative microbiological evaluation. They used scanning electron microscopy (SEM) to assess morphological changes in endodontically processed and laser-irradiated root canal walls. They measured temperature increases on the root surface to determine possible thermal side effects. The bacteriological evaluation revealed a disinfecting effect in the root dentin samples that was dependent on the output power but not specific for the bacterial species investigated. SEM showed the removal of the smear layer from the root canal walls and the exposure of dentinal tubules. The temperature rise during irradiation was moderate when standardized power settings were used. The Er,Cr:YSGG laser can be used to eliminate bacteria in root canals. It also effectively removes smear layer and debris from the canal wall. Practitioners can use the Er,Cr:YSGG laser to prepare root canals for endodontic therapy.

  20. Aluminum-Scandium Alloys: Material Characterization, Friction Stir Welding, and Compatibility With Hydrogen Peroxide (MSFC Center Director's Discretionary Fund Final Report, Proj. No. 04-14)

    Science.gov (United States)

    Lee, J. A.; Chen, P. S.

    2004-01-01

    This Technical Memorandum describes the development of several high-strength aluminum (Al) alloys that are compatible with hydrogen peroxide (H2O2) propellant for NASA Hypersonic-X (Hyper-X) vehicles fuel tanks and structures. The yield strengths for some of these Al-magnesium-based alloys are more than 3 times stronger than the conventional 5254-H112 Al alloy, while maintaining excellent H2O2 compatibility similar to class 1 5254 alloy. The alloy development strategy is to add scandium, zirconium, and other transitional metals with unique electrochemical properties, which will not act as catalysts, to decompose the highly concentrated 90 percent H2O2. Test coupons are machined from sheet metals for H2O2 long-term exposure testing and mechanical properties testing. In addition, the ability to weld the new alloys using friction stir welding has also been explored. The new high-strength alloys could represent an enabling material technology for Hyper-X vehicles, where flight weight reduction is a critical requirement.

  1. High-fluence and high-density treatment of perioral rhytides using a new, fractionated 2,790-nm ablative erbium-doped Yttrium Scandium Gallium Garnet Laser.

    Science.gov (United States)

    Ciocon, David H; Hussain, Mussarat; Goldberg, David J

    2011-06-01

    In this study, we evaluated the safety and efficacy of a novel 2,790-nm erbium-doped yttrium scandium gallium garnet (Er:YSGG) laser system for the treatment of facial photodamage and perioral wrinkles using a single-treatment, high-fluence, high-density protocol. Eleven female participants with Fitzpatrick skin types II to III and facial wrinkles underwent a single full-face fractional ablative treatment with a 2,790-nm Er:YSGG laser. Follow-up visits were completed at 1, 2, and 6 weeks 3 and 6 months. Quartile improvement scale (0-4) and Fitzpatrick wrinkle scores (1-9) were used for the assessments. Based on blinded photographic assessments, the mean difference in Fitzpatrick wrinkle scores for full face wrinkles was 1.5 ± 1.2 (a reduction from 6.6 to 5.1; paired t-test, p = .003). There was also a statistically significant mean reduction of 1.7 ± 1.3 in perioral wrinkle scores (from 6.7 to 5.0; p = .002). No serious adverse events were reported. A novel, fractionated, ablative 2,790-nm Er:YSGG laser can safely and effectively treat photodamage and perioral wrinkles in a single treatment using a high-fluence, high-density protocol. Cutera provided the equipment used in this study and funding to Dr. Goldberg. © 2011 by the American Society for Dermatologic Surgery, Inc.

  2. Impact of layer and substrate properties on the surface acoustic wave velocity in scandium doped aluminum nitride based SAW devices on sapphire

    Energy Technology Data Exchange (ETDEWEB)

    Gillinger, M., E-mail: manuel.gillinger@tuwien.ac.at; Knobloch, T.; Schneider, M.; Schmid, U. [Institute of Sensor and Actuator Systems, TU Wien, 1040 Vienna (Austria); Shaposhnikov, K.; Kaltenbacher, M. [Institute of Mechanics and Mechatronics, TU Wien, 1040 Vienna (Austria)

    2016-06-06

    This paper investigates the performance of surface acoustic wave (SAW) devices consisting of reactively sputter deposited scandium doped aluminum nitride (Sc{sub x}Al{sub 1-x}N) thin films as piezoelectric layers on sapphire substrates for wireless sensor or for RF-MEMS applications. To investigate the influence of piezoelectric film thickness on the device properties, samples with thickness ranging from 500 nm up to 3000 nm are fabricated. S{sub 21} measurements and simulations demonstrate that the phase velocity is predominantly influenced by the mass density of the electrode material rather than by the thickness of the piezoelectric film. Additionally, the wave propagation direction is varied by rotating the interdigital transducer structures with respect to the crystal orientation of the substrate. The phase velocity is about 2.5% higher for a-direction compared to m-direction of the sapphire substrate, which is in excellent agreement with the difference in the anisotropic Young's modulus of the substrate corresponding to these directions.

  3. 30 CFR 57.18010 - First aid.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false First aid. 57.18010 Section 57.18010 Mineral... Underground § 57.18010 First aid. An individual capable of providing first aid shall be available on all... artificial respiration; control bleeding; and treat shock, wounds, burns, and musculoskeletal injuries. First...

  4. 30 CFR 57.19024 - Retirement criteria.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Retirement criteria. 57.19024 Section 57.19024 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Wire Ropes § 57.19024 Retirement criteria. Unless damage or deterioration is removed by cutoff, wire...

  5. 30 CFR 57.9313 - Roadway maintenance.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Roadway maintenance. 57.9313 Section 57.9313 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... § 57.9313 Roadway maintenance. Water, debris, or spilled material on roadways which creates hazards to...

  6. 30 CFR 57.4104 - Combustible waste.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Combustible waste. 57.4104 Section 57.4104... Control Prohibitions/precautions/housekeeping § 57.4104 Combustible waste. (a) Waste materials, including liquids, shall not accumulate in quantities that could create a fire hazard. (b) Waste or rags containing...

  7. 40 CFR 57.606 - Confidentiality.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Confidentiality. 57.606 Section 57.606... NONFERROUS SMELTER ORDERS Research and Development Requirements § 57.606 Confidentiality. The provisions of section 114 of the Act and 40 CFR part 2 shall govern the confidentiality of any data or information...

  8. 42 CFR 136a.57 - Confidentiality.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Confidentiality. 136a.57 Section 136a.57 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT... Service Facilities and Indian Health Service Programs § 136a.57 Confidentiality. Information which is...

  9. 42 CFR 136.57 - Confidentiality.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Confidentiality. 136.57 Section 136.57 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES INDIAN HEALTH SERVICE, DEPARTMENT... Service Facilities and Indian Health Service Programs § 136.57 Confidentiality. Information which is...

  10. 40 CFR 57.106 - Expiration date.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Expiration date. 57.106 Section 57.106 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PRIMARY NONFERROUS SMELTER ORDERS General § 57.106 Expiration date. Each NSO shall state its expiration date. No NSO...

  11. 30 CFR 57.12006 - Distribution boxes.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Distribution boxes. 57.12006 Section 57.12006... and Underground § 57.12006 Distribution boxes. Distribution boxes shall be provided with a... deenergized, and the distribution box shall be labeled to show which circuit each device controls. ...

  12. 30 CFR 57.19022 - Initial measurement.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Initial measurement. 57.19022 Section 57.19022... Wire Ropes § 57.19022 Initial measurement. After initial rope stretch but before visible wear occurs... interval of active length and the measurements averaged to establish a baseline for subsequent measurements...

  13. 7 CFR 900.57 - Intervention.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Intervention. 900.57 Section 900.57 Agriculture... Governing Proceedings on Petitions To Modify or To Be Exempted From Marketing Orders § 900.57 Intervention. Intervention in proceedings subject to this subpart shall not be allowed, except that, in the discretion of the...

  14. 14 CFR 415.57 - Payload review.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Payload review. 415.57 Section 415.57... TRANSPORTATION LICENSING LAUNCH LICENSE Payload Review and Determination § 415.57 Payload review. (a) Timing. A payload review may be conducted as part of a license application review or may be requested by a payload...

  15. 30 CFR 57.3461 - Rock bursts.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Rock bursts. 57.3461 Section 57.3461 Mineral...-Underground Only § 57.3461 Rock bursts. (a) Operators of mines which have experienced a rock burst shall— (1) Within twenty four hours report to the nearest MSHA office each rock burst which: (i) Causes persons to...

  16. 30 CFR 57.6601 - Grounding.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding. 57.6601 Section 57.6601 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND...-Surface and Underground § 57.6601 Grounding. Electric blasting circuits, including powerline sources when...

  17. 14 CFR 1260.57 - New technology.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false New technology. 1260.57 Section 1260.57... Special Conditions § 1260.57 New technology. New Technology October 2000 (a) Definitions. Administrator... and disclosed to Recipient personnel responsible for the administration of this New Technology special...

  18. 30 CFR 57.11052 - Refuge areas.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Refuge areas. 57.11052 Section 57.11052 Mineral... Escapeways-Underground Only § 57.11052 Refuge areas. Refuge areas shall be— (a) Of fire-resistant construction, preferably in untimbered areas of the mine; (b) Large enough to accommodate readily the normal...

  19. 30 CFR 57.8528 - Unventilated areas.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Unventilated areas. 57.8528 Section 57.8528 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Underground Only § 57.8528 Unventilated areas. Unventilated areas shall be sealed, or barricaded and posted...

  20. 30 CFR 57.4501 - Fuel lines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fuel lines. 57.4501 Section 57.4501 Mineral... Installation/construction/maintenance § 57.4501 Fuel lines. Fuel lines shall be equipped with valves capable of stopping the flow of fuel at the source and shall be located and maintained to minimize fire hazards. This...

  1. 30 CFR 57.6902 - Excessive temperatures.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Excessive temperatures. 57.6902 Section 57.6902... Requirements-Surface and Underground § 57.6902 Excessive temperatures. (a) Where heat could cause premature... shall— (1) Measure an appropriate number of blasthole temperatures in order to assess the specific mine...

  2. 30 CFR 57.15003 - Protective footwear.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protective footwear. 57.15003 Section 57.15003... Surface and Underground § 57.15003 Protective footwear. All persons shall wear suitable protective footwear when in or around an area of a mine or plant where a hazard exists which could cause an injury to...

  3. 28 CFR 345.57 - Administrative pay.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Administrative pay. 345.57 Section 345.57... (FPI) INMATE WORK PROGRAMS Inmate Pay and Benefits § 345.57 Administrative pay. An inmate excused from a job assignment may receive administrative pay for such circumstances as a general recall for an...

  4. 14 CFR 63.57 - Skill requirements.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Skill requirements. 63.57 Section 63.57 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN CERTIFICATION: FLIGHT CREWMEMBERS OTHER THAN PILOTS Flight Navigators § 63.57 Skill requirements. (a) An...

  5. 7 CFR 201.57 - Hard seeds.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Hard seeds. 201.57 Section 201.57 Agriculture..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Germination Tests in the Administration of the Act § 201.57 Hard seeds. Seeds which remain hard at...

  6. 30 CFR 57.19035 - Headframe design.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Headframe design. 57.19035 Section 57.19035 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Headframes and Sheaves § 57.19035 Headframe design. All headframes shall be constructed with suitable design...

  7. 38 CFR 3.57 - Child.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Child. 3.57 Section 3.57..., and Dependency and Indemnity Compensation Relationship § 3.57 Child. (a) General. (1) Except as provided in paragraphs (a)(2) and (3) of this section, the term child of the veteran means an unmarried...

  8. 30 CFR 57.6502 - Safety fuse.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Safety fuse. 57.6502 Section 57.6502 Mineral...-Surface and Underground § 57.6502 Safety fuse. (a) The burning rate of each spool of safety fuse to be used shall be measured, posted in locations which will be conspicuous to safety fuse users, and brought...

  9. 42 CFR 60.57 - Reports.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Reports. 60.57 Section 60.57 Public Health PUBLIC... The School § 60.57 Reports. A school must submit reports to the Secretary at the times and in the manner the Secretary may reasonably prescribe. The school must retain a copy of each report for not less...

  10. 10 CFR 95.57 - Reports.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 2 2010-01-01 2010-01-01 false Reports. 95.57 Section 95.57 Energy NUCLEAR REGULATORY... RESTRICTED DATA Control of Information § 95.57 Reports. Each licensee, certificate holder, or other person having a facility clearance shall report to the CSA and the Regional Administrator of the appropriate NRC...

  11. 30 CFR 57.12021 - Danger signs.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Danger signs. 57.12021 Section 57.12021 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Underground § 57.12021 Danger signs. Suitable danger signs shall be posted at all major electrical...

  12. 30 CFR 57.4101 - Warning signs.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Warning signs. 57.4101 Section 57.4101 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Prohibitions/precautions/housekeeping § 57.4101 Warning signs. Readily visible signs prohibiting smoking and...

  13. 49 CFR 5.7 - Regulatory docket.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Regulatory docket. 5.7 Section 5.7 Transportation Office of the Secretary of Transportation RULEMAKING PROCEDURES General § 5.7 Regulatory docket. (a) Records of the Office of the Secretary of Transportation concerning rulemaking actions, including notices...

  14. 30 CFR 57.12004 - Electrical conductors.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electrical conductors. 57.12004 Section 57... Surface and Underground § 57.12004 Electrical conductors. Electrical conductors shall be of a sufficient... operations will not damage the insulating materials. Electrical conductors exposed to mechanical damage shall...

  15. 7 CFR 400.57 - [Reserved

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 6 2010-01-01 2010-01-01 false 400.57 Section 400.57 Agriculture Regulations of the Department of Agriculture (Continued) FEDERAL CROP INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE GENERAL ADMINISTRATIVE REGULATIONS Actual Production History § 400.57 ...

  16. 30 CFR 57.12085 - Transformer stations.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Transformer stations. 57.12085 Section 57.12085 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Underground Only § 57.12085 Transformer stations. Transformer stations shall be enclosed to prevent persons...

  17. 40 CFR 204.57-4 - Testing.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Testing. 204.57-4 Section 204.57-4... STANDARDS FOR CONSTRUCTION EQUIPMENT Portable Air Compressors § 204.57-4 Testing. (a) The manufacturer shall... selected for testing pursuant to this subpart. (b) No maintenance will be performed on test compressors...

  18. 30 CFR 57.5067 - Engines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Engines. 57.5067 Section 57.5067 Mineral... Agents, and Diesel Particulate Matter Diesel Particulate Matter-Underground Only § 57.5067 Engines. (a) Any diesel engine introduced into an underground area of a mine covered by this part after July 5...

  19. 7 CFR 57.10 - Administration.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Administration. 57.10 Section 57.10 Agriculture... PRODUCTS INSPECTION ACT) Regulations Governing the Inspection of Eggs General § 57.10 Administration. The... require in the enforcement or administration of the provisions of the act and the regulations in this part...

  20. 40 CFR 57.502 - Evaluation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Evaluation. 57.502 Section 57.502... NONFERROUS SMELTER ORDERS Fugitive Emission Evaluation and Control § 57.502 Evaluation. (a) Evaluation at the... their effects upon ambient air quality. (b) Evaluation during the first 6 months of the NSO. The design...

  1. 30 CFR 57.16016 - Lift trucks.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lift trucks. 57.16016 Section 57.16016 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... § 57.16016 Lift trucks. Fork and other similar types of lift trucks shall be operated with the: (a...

  2. 47 CFR 76.57 - Channel positioning.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false Channel positioning. 76.57 Section 76.57... CABLE TELEVISION SERVICE Carriage of Television Broadcast Signals § 76.57 Channel positioning. (a) At... obligations, a cable operator shall carry such signal on the cable system channel number on which the local...

  3. 30 CFR 57.11013 - Conveyor crossovers.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor crossovers. 57.11013 Section 57.11013... Escapeways Travelways-Surface and Underground § 57.11013 Conveyor crossovers. Crossovers shall be provided where it is necessary to cross conveyors. ...

  4. 30 CFR 57.19009 - Position indicator.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Position indicator. 57.19009 Section 57.19009 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Hoists § 57.19009 Position indicator. An accurate and reliable indicator of the position of the cage...

  5. 30 CFR 57.7010 - Power failures.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Power failures. 57.7010 Section 57.7010 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND... Drilling-Surface Only § 57.7010 Power failures. In the event of power failure, drill controls shall be...

  6. Structure and temperature effects on Nd3+ spectra in polycrystalline mixed scandium aluminum garnets Y3ScxAl5-xO12

    Science.gov (United States)

    Lupei, A.; Lupei, V.; Hau, S.; Gheorghe, C.; Voicu, F.

    2015-09-01

    New spectroscopic data obtained from high resolution low temperature absorption and emission spectra of Nd3+ in mixed scandium aluminum garnets Y3ScxAl5-xO12 - (x = 0-2) translucent ceramics revealed transition dependent composition effects: modification of the shapes (Lorentz at x = 0 and 2, quasi-Gauss at x = 1, x-dependent asymmetric for other x values, with obvious multicenter structure for low x), widths and shifts of the lines. Nd3+ electronic structure dependence on structural changes with composition is analyzed in terms of nephelauxetic effect and maximum splitting of manifolds: Sc3+ co-doping reduces the nephelauxetic effect, and the increase of 4F3/2 splitting from 85 cm-1 (x = 0) to 98 cm-1 (x = 2) denotes the lowering of local symmetry. The multicenter structure and inhomogeneous broadening of Nd3+ lines is attributed to crystal field distributions determined by the random occupancy of the octahedral sites by Sc3+ and Al3+. For low x (0.2) the resolved two satellites S1, S2 that accompany Nd:YAG lines are correlated to anisotropic crystal field perturbations produced by the n.n. Sc3+ by analogy to those determined by Y3+-antisites (excess of Y3+ ions that enter in octahedral sites of the melt-grown YAG crystals). The temperature evolution of the Nd3+ spectral characteristics (line intensity, shift, broadening) in the 10-300 K range is analyzed in terms of thermal population of the Stark levels, of the effect on electron-phonon interaction and on lattice expansion. The relevance of the spectroscopic properties on the laser emission characteristics in these systems is discussed.

  7. Dissolved scandium, yttrium, and lanthanum in the surface waters of the North Atlantic: Potential use as an indicator of scavenging intensity

    Science.gov (United States)

    Till, C. P.; Shelley, R. U.; Landing, W. M.; Bruland, K. W.

    2017-08-01

    Recent work has begun to elucidate the biogeochemical cycling of scandium (Sc) in the open ocean, but so far no surface distribution data have been reported of dissolved Sc, and no basin-scale surface distributions have been reported of yttrium (Y) or lanthanum (La). This work presents basin-wide surface Sc, Y, and La data in a section across the North Atlantic subtropical gyre (2011 GEOTRACES GA03) and investigates the potential utility of these distributions. This work uses dissolved and aerosol concentration data for La and Sc to estimate their surface ocean residence times in both the center of the oligotrophic gyre and near the African coastline. This work additionally shows that the surface distribution of Sc in the North Atlantic correlates with the shape of the gyre as inferred by isotherm depth, with lower Sc concentrations at the gyre boundaries. This pattern suggests that Sc could be drawn down by the elevated particle flux at the gyre boundaries. In this case, Sc removal could be used as an indicator of scavenging intensity. In order to account for variable input of Sc to the surface ocean, we propose normalizing the Sc distribution to that of Y or La, which are much less particle reactive and are input via dust to the surface North Atlantic in constant ratios with Sc. Such normalization improves the correlation with isotherm depth. We propose that the variations in dissolved Y/Sc and La/Sc ratios may be due to preferential Sc scavenging and could therefore indicate scavenging intensity.

  8. On new ternary equiatomic scandium transition metal aluminum compounds ScTAl with T = Cr, Ru, Ag, Re, Pt, and Au

    Energy Technology Data Exchange (ETDEWEB)

    Radzieowski, Mathis; Janka, Oliver [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Benndorf, Christopher [Muenster Univ. (Germany). Inst. fuer Anorganische und Analytische Chemie; Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Haverkamp, Sandra [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; Eckert, Hellmut [Muenster Univ. (Germany). Inst. fuer Physikalische Chemie; University of Sao Paulo, Sao Carlos, SP (Brazil). Inst. of Physics

    2016-08-01

    The new equiatomic scandium transition metal aluminides ScTAl for T = Cr, Ru, Ag, Re, Pt, and Au were obtained by arc-melting of the elements followed by subsequent annealing for crystal growth. The samples were studied by powder and single crystal X-ray diffraction. The structures of three compounds were refined from single crystal X-ray diffractometer data: ScCrAl, MgZn{sub 2} type, P6{sub 3}/mmc, a = 525.77(3), c = 858.68(5) pm, R{sub 1} = 0.0188, wR{sub 2} = 0.0485, 204 F{sup 2} values, 13 variables, ScPtAl, TiNiSi type, Pnma, a = 642.83(4), b = 428.96(2), c = 754.54(5) pm, R{sub 1} = 0.0326, wR{sub 2} = 0.0458, 448 F{sup 2} values, 20 variables and ScAuAl, HfRhSn type, P anti 62c, a = 722.88(4), c = 724.15(4) pm, R{sub 1} = 0.0316, wR{sub 2} = 0.0653, 512 F{sup 2} values, 18 variables. Phase pure samples of all compounds were furthermore investigated by magnetic susceptibility measurements, and Pauli-paramagnetism but no superconductivity was observed down to 2.1 K for all of them. The local structural features and disordering phenomena have been characterized by {sup 27}Al and {sup 45}Sc magic angle spinning (MAS) and static NMR spectroscopic investigations.

  9. Treatment of infraorbital dark circles in atopic dermatitis with a 2790-nm erbium: yttrium scandium gallium garnet laser: a pilot study.

    Science.gov (United States)

    Park, Kui Young; Oh, In Young; Moon, Nam Ju; Seo, Seong Jun

    2013-04-01

    Although many Asian atopic patients have orbital darkening symptom and the demand to treat this condition is increasing, little has been reported in the literature on the treatment of infraorbital dark circles in atopic dermatitis. To evaluate the clinical efficacy and safety of 2790-nm erbium:yttrium scandium gallium garnet (Er:YSGG) laser therapy for reducing infraorbital dark circles in atopic dermatitis patients. Ten Korean patients over 21 year with mild atopic dermatitis and infraorbital dark circles were enrolled in this study. Patients who need active atopic dermatitis treatments are excluded because of the possibility of aggravation after laser treatment. They were treated for dark circles using a 2790-nm Er:YSGG laser. The treatment parameters were 1.8-2.2 J/cm² fluence, 6-mm spot size, and 0.3-ms pulse width with 10% overlap over the infraorbital areas once with a 4-week interval between treatments. Efficacy was assessed with a quartile grading score ranging from 0 to 5 by a blinded investigator, and the patients also documented their degree of satisfaction with the same grading score. All possible side effects were evaluated. The clinical assessment showed 74.5% (2.7) and 72.5% (2.5) improvements, and the patient satisfaction scale scores improved an average of 74% (2.4) and 71.5% (2.3) at 2 months and 4 months after treatment, respectively. There were no severe side effects or aggravation of atopic dermatitis. Our study suggests that 2790-nm Er:YSGG laser therapy can be effectively and safely used in the treatment of infraorbital dark circles in atopic dermatitis patients.

  10. The influence of cation ordering, oxygen vacancy distribution and proton siting on observed properties in ceramic electrolytes: the case of scandium substituted barium titanate.

    Science.gov (United States)

    Torino, Nico; Henry, Paul F; Knee, Christopher S; Bjørheim, Tor Svendsen; Rahman, Seikh M H; Suard, Emma; Giacobbe, Carlotta; Eriksson, Sten G

    2017-07-04

    The origin of the 2-order of magnitude difference in the proton conductivity of the hydrated forms of hexagonal and cubic oxygen deficient BaScxTi1-xO3-δ (x = 0.2 and x = 0.7) was probed using a combination of neutron diffraction and density functional theory techniques to support published X-ray diffraction, conductivity, thermogravimetric and differential scanning calorimetry studies. Cation ordering is found in the 6H structure type (space group P63/mmc) adopted by BaSc0.2Ti0.8O3-δ with scandium preferentially substituting in the vertex sharing octahedra (2a crystallographic site) and avoiding the face-sharing octahedra (4f site). This is coupled with oxygen vacancy ordering in the central plane of the face-sharing octahedra (O1 site). In BaSc0.7Ti0.3O3-δ a simple cubic perovskite (space group Pm3[combining macron]m) best represents the average structure from Rietveld analysis with no evidence of either cation ordering or oxygen vacancy ordering. Significant diffuse scattering is observed, indicative of local order. Hydration in both cases leads to complete filling of the available oxygen vacancies and permits definition of the proton sites. We suggest that the more localised nature of the proton sites in the 6H structure is responsible for the significantly lower proton conduction observed in the literature. Within the 6H structure type final model, proton diffusion requires a 3-step process via higher energy proton sites that are unoccupied at room temperature and is also likely to be anisotropic whereas the highly disordered cubic perovskite proton position allows 3-dimensional diffusion by well-described modes. Finally, we propose how this knowledge can be used to further materials design for ceramic electrolytes for proton conducting fuel cells.

  11. 30 CFR 57.9305 - Truck spotters.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Truck spotters. 57.9305 Section 57.9305 Mineral....9305 Truck spotters. (a) If truck spotters are used, they shall be in the clear while trucks are backing into dumping position or dumping. (b) Spotters shall use signal lights to direct trucks where...

  12. 7 CFR 57.119 - Political activity.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Political activity. 57.119 Section 57.119 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE...

  13. 7 CFR 57.100 - Specific exemptions.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Specific exemptions. 57.100 Section 57.100 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... processing in nonofficial plants, including but not limited to bakeries, restaurants, and other food...

  14. 17 CFR 201.57 - Commission review.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Commission review. 201.57... Regulations Pertaining to the Equal Access to Justice Act § 201.57 Commission review. In accordance with the... Division of the Commission may seek review of the initial decision on the fee application, or the...

  15. 30 CFR 57.9309 - Chute design.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Chute design. 57.9309 Section 57.9309 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND....9309 Chute design. Chute-loading installations shall be designed to provide a safe location for persons...

  16. 30 CFR 57.17010 - Electric lamps.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Electric lamps. 57.17010 Section 57.17010 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE....17010 Electric lamps. Individual electric lamps shall be carried for illumination by all persons...

  17. 7 CFR 1753.57 - Procedures.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Procedures. 1753.57 Section 1753.57 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE TELECOMMUNICATIONS SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Outside Plant Major Construction by Force Account...

  18. 18 CFR 367.57 - Equipment.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Equipment. 367.57... Property Instructions § 367.57 Equipment. (a) The cost of equipment chargeable to the service company property accounts, unless otherwise indicated in the text of an equipment account, includes the related net...

  19. 30 CFR 57.20008 - Toilet facilities.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Toilet facilities. 57.20008 Section 57.20008....20008 Toilet facilities. (a) Toilet facilities shall be provided at locations that are compatible with... kept clean and sanitary. Separate toilet facilities shall be provided for each sex except where toilet...

  20. 30 CFR 57.9308 - Switch throws.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Switch throws. 57.9308 Section 57.9308 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND....9308 Switch throws. Switch throws shall be installed to provide clearance to protect switchmen from...

  1. 30 CFR 57.20002 - Potable water.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Potable water. 57.20002 Section 57.20002....20002 Potable water. (a) An adequate supply of potable drinking water shall be provided at all active working areas. (b) The common drinking cup and containers from which drinking water must be dipped or...

  2. 36 CFR 251.57 - Rental fees.

    Science.gov (United States)

    2010-07-01

    ... covering more than one year. (3) A base cabin user fee for a recreation residence use shall be 5 percent of... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Rental fees. 251.57 Section... Uses § 251.57 Rental fees. (a) Except as otherwise provided in this part or when specifically...

  3. 7 CFR 57.240 - Detaining product.

    Science.gov (United States)

    2010-01-01

    ... product, and the custodian or owner shall be given a written notice of such detention. Only authorized... 7 Agriculture 3 2010-01-01 2010-01-01 false Detaining product. 57.240 Section 57.240 Agriculture... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) INSPECTION OF EGGS (EGG...

  4. 30 CFR 57.19045 - Metal bonnets.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Metal bonnets. 57.19045 Section 57.19045 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Personnel Hoisting...

  5. 7 CFR 57.130 - Identification.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Identification. 57.130 Section 57.130 Agriculture... Identification. Each inspector shall have in their possession at all times, and present while on duty upon request, the means of identification furnished by the Department. [69 FR 57167, Sept. 24, 2004] ...

  6. Effects of erbium-and chromium-doped yttrium scandium gallium garnet and diode lasers on the surfaces of restorative dental materials: a scanning electron microscope study.

    Science.gov (United States)

    Hatipoglu, M; Barutcigil, C

    2015-01-01

    The aim of this study is to evaluate the potential effects of laser irradiation, which is commonly performed in periodontal surgery, on the surfaces of restorative materials. Five different restorative dental materials were used in this study, as follows: (1) Resin composite, (2) poly acid-modified resin composite (compomer), (3) conventional glass ionomer cement (GIC), (4) resin-modified glass ionomer cement (RMGIC), and (5) amalgam. Four cylindrical samples (8 mm diameter, 2 mm height) were prepared for each restorative material. In addition, four freshly extracted, sound human incisors teeth were selected. Two different laser systems commonly used in periodontal surgery were examined in this study: A 810 nm diode laser at a setting of 1 W with continuous-phase laser irradiation for 10 s, and an erbium-and chromium-doped yttrium scandium gallium garnet (Er, Cr: YSGG) laser at settings of 2.5 W, 3.25 W, and 4 W with 25 Hz laser irradiation for 10 s. Scanning electron microscopy (SEM) analysis was performed to evaluate the morphology and surface deformation of the restorative materials and tooth surfaces. According to the SEM images, the Er, Cr: YSGG laser causes irradiation markings that appear as demineralized surfaces on tooth samples. The Er, Cr: YSGG laser also caused deep defects on composite, compomer, and RMGIC surfaces because of its high power, and the ablation was deeper for these samples. High-magnification SEM images of GIC samples showed the melting and combustion effects of the Er, Cr: YSGG laser, which increased as the laser power was increased. In amalgam samples, neither laser left significant harmful effects at the lowest power setting. The diode laser did cause irradiation markings, but they were insignificant compared with those left by the Er, Cr: YSGG laser on the surfaces of the different materials and teeth. Within the limitations of this study, it can be concluded that Er, Cr: YSGG laser irradiation could cause distortions of the surfaces

  7. The exciting star of HH 57

    Science.gov (United States)

    Cohen, M.; Dopita, M. A.; Schwartz, R.

    1986-01-01

    The first spectral classification for the exciting star of HH 57 is provided. The star is an F8 III and suffers about 5 mag of visual extinction, far greater than that toward the HH 57A knot, only a few arcseconds away. This difference supports the previous identification of a flattened geometry for the circumstellar dust around this star. Using IRAS photometry, a distance of 940 pc to HH 57 is determined by bolometrically matching the observed luminosity of the star to those of FU Ori and V1057 Cyg.

  8. Performance of I-57 recycled concrete pavements.

    Science.gov (United States)

    2009-01-01

    In 1986-1987 the Illinois Department of Transportation (IDOT) constructed a demonstration project on I-57 near Effingham, Illinois to evaluate the viability : of recycling an existing jointed reinforced concrete pavement for use as its primary aggreg...

  9. Influence of c-axis orientation and scandium concentration on infrared active modes of magnetron sputtered Sc{sub x}Al{sub 1−x}N thin films

    Energy Technology Data Exchange (ETDEWEB)

    Mayrhofer, P. M.; Bittner, A.; Schmid, U. [Institute of Sensor and Actuator Systems, Vienna University of Technology, Floragasse 7, 1040 Vienna (Austria); Eisenmenger-Sittner, C. [Institute of Solid State Physics, Vienna University of Technology, Wiedner Hauptstrasse 8, 1040 Vienna (Austria); Euchner, H. [Institute of Materials Science and Technology, Vienna University of Technology, Karlsplatz 13, 1040 Vienna (Austria)

    2013-12-16

    Doping of wurtzite aluminium nitride (AlN) with scandium (Sc) significantly enhances the piezoelectric properties of AlN. Sc{sub x}Al{sub 1−x}N thin films with different Sc concentrations (x = 0 to 0.15) were deposited by DC reactive magnetron sputtering. Infrared (IR) absorbance spectroscopy was applied to investigate the Sc concentration dependent shift of the IR active modes E{sub 1}(TO) and A{sub 1}(TO). These results are compared to ab initio simulations, being in excellent agreement with the experimental findings. In addition, IR spectroscopy is established as an economical and fast method to distinguish between thin films with a high degree of c-axis orientation and those exhibiting mixed orientations.

  10. 30 CFR 57.4600 - Extinguishing equipment.

    Science.gov (United States)

    2010-07-01

    ....4600 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Welding/cutting/compressed Gases § 57.4600 Extinguishing equipment. (a) When welding...

  11. 30 CFR 57.13030 - Boilers.

    Science.gov (United States)

    2010-07-01

    ... Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Compressed Air and Boilers § 57... Specifications—Part B—Non-ferrous IIMaterial Specifications—Part C—Welding Rods, Electrodes, and Filler Metals...

  12. 45 CFR 1355.57 - Cost allocation.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF HEALTH AND HUMAN SERVICES THE ADMINISTRATION ON CHILDREN, YOUTH AND FAMILIES, FOSTER CARE MAINTENANCE PAYMENTS, ADOPTION ASSISTANCE, AND CHILD AND FAMILY SERVICES GENERAL § 1355.57 Cost allocation. (a... may be used with respect to foster or adoptive children other than those on behalf of whom foster care...

  13. 40 CFR 57.102 - Eligibility.

    Science.gov (United States)

    2010-07-01

    ... NONFERROUS SMELTER ORDERS General § 57.102 Eligibility. (a) A primary copper, lead, zinc, molybdenum, or... promulgated sulfur dioxide (SO2) State Implementation Plan (SIP) emission limitation which is adequate to...) Replacement or process modifications. (A) Flash smelting; (B) Oxygen enrichment; (C) Supplemental sulfur...

  14. 7 CFR 51.57 - Facilities.

    Science.gov (United States)

    2010-01-01

    ... Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946... Requirements for Plants Operating Under Continuous Inspection on A Contract Basis § 51.57 Facilities. Each...

  15. 32 CFR 57.3 - Definitions.

    Science.gov (United States)

    2010-07-01

    ..., inclusive, with a disability to benefit from special education under the child's IEP. The term includes... INTERVENTION AND SPECIAL EDUCATION SERVICES TO ELIGIBLE DOD DEPENDENTS § 57.3 Definitions. (a) Age of Majority... special education and related services as “other health impaired” by reason of the disability if the child...

  16. 27 CFR 25.57 - Formula information.

    Science.gov (United States)

    2010-04-01

    ... that covers the production of any beer base used in producing the formula product. If the beer base was... OF THE TREASURY LIQUORS BEER Miscellaneous Provisions Formulas § 25.57 Formula information. (a... content of the flavor; and the point of production at which the flavor was added (that is, before, during...

  17. 12 CFR 229.57 - Consumer awareness.

    Science.gov (United States)

    2010-01-01

    ... substitute check is the legal equivalent of an original check; and (2) The consumer recredit rights that apply when a consumer in good faith believes that a substitute check was not properly charged to his or... AVAILABILITY OF FUNDS AND COLLECTION OF CHECKS (REGULATION CC) Substitute Checks § 229.57 Consumer awareness...

  18. 42 CFR 57.2002 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Armed Forces Health Professions Scholarship Program § 57.2002 Definitions. As used in this subpart: (a) Institution means a college, university, or other institution or a department, division, or other administrative unit within a college...

  19. 40 CFR 57.403 - Written consent.

    Science.gov (United States)

    2010-07-01

    ... NONFERROUS SMELTER ORDERS Supplementary Control System Requirements § 57.403 Written consent. (a) The consent... violation of the National Ambient Air Quality Standards for sulfur dioxide in the smelter's designated... of, and obtain data from ambient air quality monitors operated by the company under the requirements...

  20. Hyperfine electric parameters calculation in Si samples implanted with {sup 57}Mn→{sup 57}Fe

    Energy Technology Data Exchange (ETDEWEB)

    Abreu, Y., E-mail: yabreu@ceaden.edu.cu [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear (CEADEN), Calle 30 No. 502 e/5ta y 7ma Ave., 11300 Miramar, Playa, La Habana (Cuba); Cruz, C.M.; Piñera, I.; Leyva, A.; Cabal, A.E. [Centro de Aplicaciones Tecnológicas y Desarrollo Nuclear (CEADEN), Calle 30 No. 502 e/5ta y 7ma Ave., 11300 Miramar, Playa, La Habana (Cuba); Van Espen, P. [Departement Chemie, Universiteit Antwerpen, Middelheimcampus, G.V.130, Groenenborgerlaan 171, 2020 Antwerpen (Belgium); Van Remortel, N. [Departement Fysica, Universiteit Antwerpen, Middelheimcampus, G.U.236, Groenenborgerlaan 171, 2020 Antwerpen (Belgium)

    2014-07-15

    Nowadays the electronic structure calculations allow the study of complex systems determining the hyperfine parameters measured at a probe atom, including the presence of crystalline defects. The hyperfine electric parameters have been measured by Mössbauer spectroscopy in silicon materials implanted with {sup 57}Mn→{sup 57}Fe ions, observing four main contributions to the spectra. Nevertheless, some ambiguities still remain in the {sup 57}Fe Mössbauer spectra interpretation in this case, regarding the damage configurations and its evolution with annealing. In the present work several implantation environments are evaluated and the {sup 57}Fe hyperfine parameters are calculated. The observed correlation among the studied local environments and the experimental observations is presented, and a tentative microscopic description of the behavior and thermal evolution of the characteristic defects local environments of the probe atoms concerning the location of vacancies and interstitial Si in the neighborhood of {sup 57}Fe ions in substitutional and interstitial sites is proposed.

  1. Lift conference | 5-7 February

    CERN Multimedia

    2014-01-01

    Since 2006, Lift Events explore the business and social implications of new technologies through the organisation of international event series and open innovation programs in Europe, Asia and America. The next conference will be held on 5-7 February in Geneva.   (Image: © Lift Conference) The Lift Conference is one of the leading conferences on innovation in Europe and a key annual meeting for individuals and organizations wishing to understand and anticipate trends and innovation. Held every year in February in Geneva (5-7 February 2014), the Lift Conference is a three-day event consisting of talks, interactive workshops, exhibitions, and discussions bringing together over 1’000 participants from all society’s sectors and industries in a dynamic and informal environment with the aim to learn, connect, share and leverage innovation opportunities.   Extraordinary speakers will take to the stage at Lift14: Porter Erisman, former VP of Alibaba.com turned...

  2. 32 CFR 57.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... INTERVENTION AND SPECIAL EDUCATION SERVICES TO ELIGIBLE DOD DEPENDENTS § 57.1 Purpose. This part: (a....C. 921-932, 10 U.S.C. 2164, DoD Directive 1342.6 1 , DoD Directive 1342.21, DoD Instruction 1342.26, DoD Directive 1342.13, and DoD Directive 5105.4 for the following: 1 All unclassified DoD Directives...

  3. After Effects of the 57Co(EC)57Fe-Reaction in some Cobalt and Iron Complexes

    DEFF Research Database (Denmark)

    Siekierska, K. F.; Fenger, Jørgen Folkvard; Olsen, J.

    1972-01-01

    Mössbauer emission spectra of iron and cobalt complexes, doped or labelled with 57Co, demonstrate that the 57Co(EC)57Fe reaction can have significant chemical effects, although the probability of displacement of the nascent57Fe is very low. Measurements on specifically 57Co-labelled [Co(bipy)3][Co......(CN)6],2H2O failed to show transfer of 57Fe from one complex to the other....

  4. Two scandium-biuret complexes: [Sc(C2H5N3O2)(H2O)5]Cl3 x H2O and [Sc(C2H5N3O2)4](NO3)3.

    Science.gov (United States)

    Harrison, William T A

    2008-05-01

    The scandium(III) cations in the structures of pentaaqua(biuret-kappa(2)O,O')scandium(III) trichloride monohydrate, [Sc(C(2)H(5)N(3)O(2))(H(2)O)(5)]Cl(3) x H(2)O, (I), and tetrakis(biuret-kappa(2)O,O')scandium(III) trinitrate, [Sc(C(2)H(5)N(3)O(2))(4)](NO(3))(3), (II), are found to adopt very different coordinations with the same biuret ligand. The roles of hydrogen bonding and the counter-ion in the establishment of the structures are described. In (I), the Sc(3+) cation adopts a fairly regular pentagonal bipyramidal coordination geometry arising from one O,O'-bidentate biuret molecule and five water molecules. A dense network of N-H...Cl, O-H...O and O-H...Cl hydrogen bonds help to establish the packing, resulting in dimeric associations of two cations and two water molecules. In (II), the Sc(3+) cation (site symmetry 2) adopts a slightly squashed square-antiprismatic geometry arising from four O,O'-bidentate biuret molecules. A network of N-H...O hydrogen bonds help to establish the packing, which features [010] chains of cations. One of the nitrate ions is disordered about an inversion centre. Both structures form three-dimensional hydrogen-bond networks.

  5. [Syphilis: 57 observations in Fez, Morocco].

    Science.gov (United States)

    Gallouj, S; Bendahhou, K; Baybay, H; Benchat, L; Meziane, M; El Fakir, S; Mikou, O; Nejjari, C; Mernissi, F Z

    2011-06-01

    A prospective study of syphilis cases over a period of 2 years (January 2008 to September 2009) was carried out in the Department of Dermatology of the Hassan II University Hospital Center in Fes, Morocco. A total of 57 cases were identified. The M/F sex ratio was 0.89. Mean patient age was 40.5 years (range, 22-80). Risk factors included unprotected sex in 96.5% of cases and multiple partners in 42.1%. Nine patients had a history of sexually transmitted infection. No patient had received blood transfusion. Clinical picture was late latent syphilis in 70.2% of cases (n = 41). Only one case was associated with human immunodeficiency virus. The mainstay treatment was intramuscular benzathine benzylpenicillin. Outcome was favorable in 48 cases.

  6. 46 CFR 57.06-1 - Production test plate requirements.

    Science.gov (United States)

    2010-10-01

    .... (b) Main power boilers shall meet the test plate requirements for Class I pressure vessels. (c) Test... 46 Shipping 2 2010-10-01 2010-10-01 false Production test plate requirements. 57.06-1 Section 57... BRAZING Production Tests § 57.06-1 Production test plate requirements. (a) Production test plates shall be...

  7. 30 CFR 57.12032 - Inspection and cover plates.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Inspection and cover plates. 57.12032 Section 57.12032 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Electricity Surface and Underground § 57.12032 Inspection and cover plates. Inspection and cover plates on...

  8. 30 CFR 57.19075 - Use of open hooks.

    Science.gov (United States)

    2010-07-01

    ... SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Personnel Hoisting Hoisting Procedures § 57.19075 Use of open hooks. Open hooks shall not be used to hoist buckets or other... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Use of open hooks. 57.19075 Section 57.19075...

  9. 30 CFR 57.6205 - Conveying explosives by hand.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveying explosives by hand. 57.6205 Section 57.6205 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Transportation-Surface and Underground § 57.6205 Conveying explosives by hand. Closed, nonconductive containers...

  10. 30 CFR 57.4402 - Safety can use.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Safety can use. 57.4402 Section 57.4402 Mineral... Flammable and Combustible Liquids and Gases § 57.4402 Safety can use. Small quantities of flammable liquids drawn from storage shall be kept in safety cans labeled to indicate the contents. ...

  11. 30 CFR 57.7803 - Lighting the burner.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lighting the burner. 57.7803 Section 57.7803... Jet Piercing Rotary Jet Piercing-Surface Only § 57.7803 Lighting the burner. A suitable means of protection shall be provided for the employee when lighting the burner. ...

  12. 30 CFR 57.19103 - Dumping facilities and loading pockets.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Dumping facilities and loading pockets. 57.19103 Section 57.19103 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... MINES Personnel Hoisting Shafts § 57.19103 Dumping facilities and loading pockets. Dumping facilities...

  13. 36 CFR 1192.57 - Interior circulation, handrails and stanchions.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Interior circulation, handrails and stanchions. 1192.57 Section 1192.57 Parks, Forests, and Public Property ARCHITECTURAL AND... TRANSPORTATION VEHICLES Rapid Rail Vehicles and Systems § 1192.57 Interior circulation, handrails and stanchions...

  14. 42 CFR 57.309 - Payment of nursing student loans.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Payment of nursing student loans. 57.309 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Nursing Student Loans § 57.309 Payment of nursing student loans. (a) Nursing student loans from any fund may be paid to...

  15. 42 CFR 57.305 - Nursing student loan funds.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Nursing student loan funds. 57.305 Section 57.305... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Nursing Student Loans § 57.305 Nursing student loan funds. (a) Funds established with Federal capital contributions. Any...

  16. 30 CFR 57.12027 - Grounding mobile equipment.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding mobile equipment. 57.12027 Section 57.12027 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Surface and Underground § 57.12027 Grounding mobile equipment. Frame grounding or equivalent protection...

  17. 30 CFR 57.12025 - Grounding circuit enclosures.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding circuit enclosures. 57.12025 Section 57.12025 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Electricity Surface and Underground § 57.12025 Grounding circuit enclosures. All metal enclosing or encasing...

  18. 30 CFR 57.12028 - Testing grounding systems.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Testing grounding systems. 57.12028 Section 57.12028 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Surface and Underground § 57.12028 Testing grounding systems. Continuity and resistance of grounding...

  19. 30 CFR 57.12026 - Grounding transformer and switchgear enclosures.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Grounding transformer and switchgear enclosures. 57.12026 Section 57.12026 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... NONMETAL MINES Electricity Surface and Underground § 57.12026 Grounding transformer and switchgear...

  20. 18 CFR 2.57 - Temporary certificates-pipeline companies.

    Science.gov (United States)

    2010-04-01

    ...-pipeline companies. 2.57 Section 2.57 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... Policy and Interpretations Under the Natural Gas Act § 2.57 Temporary certificates—pipeline companies... the proposed construction is of major proportions. Pipeline companies are accordingly urged to conduct...

  1. 30 CFR 57.15005 - Safety belts and lines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Safety belts and lines. 57.15005 Section 57.15005 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Protection Surface and Underground § 57.15005 Safety belts and lines. Safety belts and lines shall be worn...

  2. 30 CFR 57.14108 - Overhead drive belts.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Overhead drive belts. 57.14108 Section 57.14108... Equipment Safety Devices and Maintenance Requirements § 57.14108 Overhead drive belts. Overhead drive belts shall be guarded to contain the whipping action of a broken belt if that action could be hazardous to...

  3. 30 CFR 57.15020 - Life jackets and belts.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Life jackets and belts. 57.15020 Section 57.15020 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Protection Surface Only § 57.15020 Life jackets and belts. Life jackets or belts shall be worn where there is...

  4. 40 CFR 57.816 - Effect of negative recommendation.

    Science.gov (United States)

    2010-07-01

    ... Reduction Technology § 57.816 Effect of negative recommendation. No waiver of the interim requirement for... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Effect of negative recommendation. 57.816 Section 57.816 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS...

  5. 40 CFR 57.202 - How to apply.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false How to apply. 57.202 Section 57.202... NONFERROUS SMELTER ORDERS The Application and the NSO Process § 57.202 How to apply. (a) Letter of intent. To... to apply for an NSO, and an agreement to provide any information required under this part. The letter...

  6. 40 CFR 57.201 - Where to apply.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Where to apply. 57.201 Section 57.201... NONFERROUS SMELTER ORDERS The Application and the NSO Process § 57.201 Where to apply. Any eligible smelter may apply for an NSO to the appropriate EPA Regional Office or to the appropriate State or local air...

  7. 46 CFR 57.05-5 - Low temperature application.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Low temperature application. 57.05-5 Section 57.05-5 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING Performance Qualifications § 57.05-5 Low temperature application. For low temperature application, each welder...

  8. 30 CFR 57.7050 - Tool and drill steel racks.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Tool and drill steel racks. 57.7050 Section 57... Rotary Jet Piercing Drilling-Surface and Underground § 57.7050 Tool and drill steel racks. Receptacles or racks shall be provided for drill steel and tools stored or carried on drills. ...

  9. 7 CFR 57.120 - Financial interest of inspectors.

    Science.gov (United States)

    2010-01-01

    ... Performance of Services § 57.120 Financial interest of inspectors. An inspector shall not inspect any product... 7 Agriculture 3 2010-01-01 2010-01-01 false Financial interest of inspectors. 57.120 Section 57... AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT...

  10. 40 CFR 57.109 - Maintenance of pay.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Maintenance of pay. 57.109 Section 57.109 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PRIMARY NONFERROUS SMELTER ORDERS General § 57.109 Maintenance of pay. The Administrator will not approve...

  11. 7 CFR 201.57a - Dormant seeds.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Dormant seeds. 201.57a Section 201.57a Agriculture..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Germination Tests in the Administration of the Act § 201.57a Dormant seeds. Dormant seeds are...

  12. 30 CFR 57.16004 - Containers for hazardous materials.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Containers for hazardous materials. 57.16004 Section 57.16004 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Storage and Handling § 57.16004 Containers for hazardous materials. Containers holding hazardous materials...

  13. 30 CFR 57.12033 - Hand-held electric tools.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hand-held electric tools. 57.12033 Section 57.12033 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Surface and Underground § 57.12033 Hand-held electric tools. Hand-held electric tools shall not be...

  14. 30 CFR 57.19094 - Posting signal code.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Posting signal code. 57.19094 Section 57.19094 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Signaling § 57.19094 Posting signal code. A legible signal code shall be posted prominently in the hoist...

  15. 30 CFR 57.19093 - Standard signal code.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Standard signal code. 57.19093 Section 57.19093 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... Signaling § 57.19093 Standard signal code. A standard code of hoisting signals shall be adopted and used at...

  16. 30 CFR 57.12036 - Fuse removal or replacement.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fuse removal or replacement. 57.12036 Section 57.12036 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Electricity Surface and Underground § 57.12036 Fuse removal or replacement. Fuses shall not be removed or...

  17. 30 CFR 57.14102 - Brakes for rail equipment.

    Science.gov (United States)

    2010-07-01

    ... Equipment Safety Devices and Maintenance Requirements § 57.14102 Brakes for rail equipment. Braking systems on railroad cars and locomotives shall be maintained in functional condition. ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Brakes for rail equipment. 57.14102 Section 57...

  18. 30 CFR 57.12080 - Bare conductor guards.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bare conductor guards. 57.12080 Section 57... Underground Only § 57.12080 Bare conductor guards. Trolley wires and bare power conductors shall be guarded at... conductors are less than 7 feet above the rail, they shall be guarded at all points where persons work or...

  19. 47 CFR 5.57 - Who may sign applications.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Who may sign applications. 5.57 Section 5.57 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL EXPERIMENTAL RADIO SERVICE (OTHER THAN BROADCAST) Applications and Licenses § 5.57 Who may sign applications. (a) Except as provided in paragraph (b) of this...

  20. 30 CFR 57.7012 - Tending drills in operation.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Tending drills in operation. 57.7012 Section 57... MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Drilling and Rotary Jet Piercing Drilling-Surface Only § 57.7012 Tending drills in operation. While in operation...

  1. 40 CFR 205.57 - Selective enforcement auditing requirements.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Selective enforcement auditing requirements. 205.57 Section 205.57 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57...

  2. 40 CFR 205.57-1 - Test request.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Test request. 205.57-1 Section 205.57-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-1 Test request. (a) The...

  3. 40 CFR 205.57-8 - Continued testing.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Continued testing. 205.57-8 Section 205.57-8 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-8 Continued...

  4. 40 CFR 205.57-4 - Testing procedures.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Testing procedures. 205.57-4 Section 205.57-4 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-4 Testing...

  5. 40 CFR 205.57-2 - Test vehicle sample selection.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Test vehicle sample selection. 205.57-2 Section 205.57-2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-2 Test...

  6. 40 CFR 205.57-3 - Test vehicle preparation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Test vehicle preparation. 205.57-3 Section 205.57-3 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-3 Test vehicle...

  7. 46 CFR 78.57-1 - All personnel must comply.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false All personnel must comply. 78.57-1 Section 78.57-1 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) PASSENGER VESSELS OPERATIONS Routing Instructions § 78.57-1 All personnel must comply. All licensed masters, officers, and certificated seamen on...

  8. 37 CFR 2.57-2.58 - [Reserved

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false 2.57-2.58 Section 2.57-2.58 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Drawing §§ 2.57-2.58 ...

  9. 42 CFR 57.2209 - Conditions of scholarship grant.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Conditions of scholarship grant. 57.2209 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2209 Conditions of scholarship grant. (a) Any scholarship grant made...

  10. 42 CFR 57.2207 - Amount of scholarship grant.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Amount of scholarship grant. 57.2207 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2207 Amount of scholarship grant. (a) The amount of the scholarship...

  11. 42 CFR 57.2208 - Payment of scholarship grant.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Payment of scholarship grant. 57.2208 Section 57... CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2208 Payment of scholarship grant. The portion of a scholarship grant...

  12. 7 CFR 27.57 - Request for postponement.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 2 2010-01-01 2010-01-01 false Request for postponement. 27.57 Section 27.57 Agriculture Regulations of the Department of Agriculture AGRICULTURAL MARKETING SERVICE (Standards....57 Request for postponement. If the applicant desires the postponement of the classification of any...

  13. 30 CFR 57.12068 - Locking transformer enclosures.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Locking transformer enclosures. 57.12068 Section 57.12068 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... Electricity Surface Only § 57.12068 Locking transformer enclosures. Transformer enclosures shall be kept...

  14. 30 CFR 57.9301 - Dump site restraints.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Dump site restraints. 57.9301 Section 57.9301 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE... § 57.9301 Dump site restraints. Berms, bumper blocks, safety hooks, or similar impeding devices shall...

  15. 30 CFR 57.19026 - Drum end attachment.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Drum end attachment. 57.19026 Section 57.19026... Wire Ropes § 57.19026 Drum end attachment. (a) For drum end attachment, wire rope shall be attached— (1... bolts, clamps, or wedges, provided that the attachment is a design feature of the hoist drum. Design...

  16. 30 CFR 57.14201 - Conveyor start-up warnings.

    Science.gov (United States)

    2010-07-01

    ... entire length of the conveyor is not visible from the starting switch, a system which provides visible or... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor start-up warnings. 57.14201 Section 57... Equipment Safety Practices and Operational Procedures § 57.14201 Conveyor start-up warnings. (a) When the...

  17. 30 CFR 57.4503 - Conveyor belt slippage.

    Science.gov (United States)

    2010-07-01

    ...) Underground belt conveyors shall be equipped with a detection system capable of automatically stopping the... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Conveyor belt slippage. 57.4503 Section 57.4503... Control Installation/construction/maintenance § 57.4503 Conveyor belt slippage. (a) Surface belt conveyors...

  18. 30 CFR 57.4263 - Underground belt conveyors.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Underground belt conveyors. 57.4263 Section 57... and Control Firefighting Equipment § 57.4263 Underground belt conveyors. Fire protection shall be provided at the head, tail, drive, and take-up pulleys of underground belt conveyors. Provisions shall be...

  19. 30 CFR 57.11009 - Walkways along conveyors.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Walkways along conveyors. 57.11009 Section 57... Escapeways Travelways-Surface and Underground § 57.11009 Walkways along conveyors. Walkways with outboard railings shall be provided wherever persons are required to walk alongside elevated conveyor belts...

  20. 30 CFR 57.11014 - Crossing moving conveyors.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Crossing moving conveyors. 57.11014 Section 57.11014 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL... Escapeways Travelways-Surface and Underground § 57.11014 Crossing moving conveyors. Moving conveyors shall be...

  1. 40 CFR 57.604 - Evaluation of projects.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 5 2010-07-01 2010-07-01 false Evaluation of projects. 57.604 Section 57.604 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PRIMARY NONFERROUS SMELTER ORDERS Research and Development Requirements § 57.604 Evaluation of projects...

  2. 28 CFR 2.57 - Special parole terms.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Special parole terms. 2.57 Section 2.57 Judicial Administration DEPARTMENT OF JUSTICE PAROLE, RELEASE, SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.57 Special parole terms. (a) The Drug Abuse Prevention...

  3. Formation of iron-57 divalent cation (57Fe2+) in Mössbauer sources of potassium trisoxalatoferrate(III)

    DEFF Research Database (Denmark)

    Fenger, Jes; Siekierska, K. E.; Maddock, A. G.

    1970-01-01

    The 57Co(electron capture)57Fe process taking place in 57Co-doped crystals of K3Fe III (C2O4)3,3H2O and K3Fe III (C2O4)3 produces some divalent 57Fe II . The reduced species may be Fe(C2O4)2 2–, which has previously been observed in γ-irradiated potassium trisoxalatoferrate(III)....

  4. KSHV ORF57, a Protein of Many Faces

    Directory of Open Access Journals (Sweden)

    Vladimir Majerciak

    2015-02-01

    Full Text Available Kaposi’s sarcoma-associated herpesvirus (KSHV ORF57 protein (also known as mRNA transcript accumulation (Mta is a potent posttranscriptional regulator essential for the efficient expression of KSHV lytic genes and productive KSHV replication. ORF57 possesses numerous activities that promote the expression of viral genes, including the three major functions of enhancement of RNA stability, promotion of RNA splicing, and stimulation of protein translation. The multifunctional nature of ORF57 is driven by its ability to interact with an array of cellular cofactors. These interactions are required for the formation of ORF57-containing ribonucleoprotein complexes at specific binding sites in the target transcripts, referred as Mta-responsive elements (MREs. Understanding of the ORF57 protein conformation has led to the identification of two structurally-distinct domains within the ORF57 polypeptide: an unstructured intrinsically disordered N-terminal domain and a structured α-helix-rich C-terminal domain. The distinct structures of the domains serve as the foundation for their unique binding affinities: the N-terminal domain mediates ORF57 interactions with cellular cofactors and target RNAs, and the C-terminal domain mediates ORF57 homodimerization. In addition, each domain has been found to contribute to the stability of ORF57 protein in infected cells by counteracting caspase- and proteasome-mediated degradation pathways. Together, these new findings provide insight into the function and biological properties of ORF57 in the KSHV life cycle and pathogenesis.

  5. Functional evolution of duplicated odorant-binding protein genes, Obp57d and Obp57e, in Drosophila.

    Directory of Open Access Journals (Sweden)

    Eriko Harada

    Full Text Available Odorant-binding proteins (OBPs are extracellular proteins found in insect chemosensilla, where they participate in the sensing of odors, tastes, and pheromones. Although a large number of OBP genes have been identified in insect genomes, their molecular functions and biological roles have been clarified in limited cases. Two OBP genes, Obp57d and Obp57e, were involved in the evolution of host-plant preference in Drosophila sechellia. Comparative analyses of the Obp57d/e genomic sequences from 27 closely related species suggested that the two genes arose by tandem gene duplication and functionally diverged from each other. In this study, the functional evolution of Obp57d and Obp57e was examined by in vitro binding assays using recombinant proteins synthesized in a bacterial system. Compared to the ancestral Dpse\\OBP57de, Dmel\\OBP57d was more specialized to tridecanoic acid while Dmel\\OBP57e was generalized regarding their binding affinity, suggesting that the two OBP genes underwent subfunctionalization and neofunctionalization. A behavioral analysis using knockout flies supported that the biological role is different between OBP57d and OBP57e in vivo. Site-directed mutagenesis of the evolutionarily conserved amino acids revealed that these residues play an important role in protein folding. These findings provide a clue to understanding how the repertoire of OBP genes is maintained in a genome under natural selection.

  6. 46 CFR 57.02-5 - Filler metals.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Filler metals. 57.02-5 Section 57.02-5 Shipping COAST... Requirements § 57.02-5 Filler metals. (a) Except as provided for in paragraph (b) of this section, when filler metal is used in a welded fabrication that is required to meet the requirements of this part the filler...

  7. 40 CFR 57.303 - Total plantwide emission limitation.

    Science.gov (United States)

    2010-07-01

    ... (CONTINUED) PRIMARY NONFERROUS SMELTER ORDERS Constant Controls and Related Requirements § 57.303 Total... direct measurements or appropriately documented mass balance calculations. (b) Compliance with the...

  8. 46 CFR 310.57 - Application and selection of midshipmen.

    Science.gov (United States)

    2010-10-01

    ... 310.57 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION TRAINING MERCHANT MARINE TRAINING Admission and Training of Midshipmen at the United States Merchant Marine Academy § 310.57... allegiance to the same; that I will comply with all the regulations of the U.S. Merchant Marine Academy; that...

  9. 30 CFR 57.4604 - Preparation of pipelines or containers.

    Science.gov (United States)

    2010-07-01

    ... Section 57.4604 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Welding/cutting/compressed Gases § 57.4604 Preparation of pipelines or containers...

  10. 32 CFR 776.57 - Unauthorized practice of law.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Unauthorized practice of law. 776.57 Section 776... Rules of Professional Conduct § 776.57 Unauthorized practice of law. (a) Unauthorized practice of law. A... law in a jurisdiction where doing so is prohibited by the regulations of the legal profession in that...

  11. 45 CFR 400.57 - Planning and consultation process.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Planning and consultation process. 400.57 Section... Refugee Cash Assistance § 400.57 Planning and consultation process. A State that wishes to establish a public/private RCA program must engage in a planning and consultation process with the local agencies...

  12. 42 CFR 410.57 - Pneumococcal vaccine and flu vaccine.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Pneumococcal vaccine and flu vaccine. 410.57... § 410.57 Pneumococcal vaccine and flu vaccine. (a) Medicare Part B pays for pneumococcal vaccine and its administration when reasonable and necessary for the prevention of disease, if the vaccine is ordered by a doctor...

  13. 7 CFR 57.35 - Eggs in commerce.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Eggs in commerce. 57.35 Section 57.35 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards... Eggs in commerce. (a)(1) For eggs that moved or are moving in interstate or foreign commerce, no State...

  14. 42 CFR 57.308 - Nursing student loan promissory note.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Nursing student loan promissory note. 57.308... Nursing Student Loans § 57.308 Nursing student loan promissory note. (a) Promissory note form. Each nursing student loan must be evidenced by a properly executed promissory note in a form approved by the...

  15. 7 CFR 57.720 - Disposition of restricted eggs.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT (CONTINUED) INSPECTION OF EGGS (EGG... decharacterized product shall be labeled as required in §§ 57.840 and 57.860. (3) By processing for industrial use... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards...

  16. 30 CFR 57.14212 - Chains, ropes, and drive belts.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Chains, ropes, and drive belts. 57.14212... and Equipment Safety Practices and Operational Procedures § 57.14212 Chains, ropes, and drive belts. Chains, ropes, and drive belts shall be guided mechanically onto moving pulleys, sprockets, or drums...

  17. 7 CFR 1714.57 - Sequence of advances.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Sequence of advances. 1714.57 Section 1714.57... Sequence of advances. (a) Except as set forth in paragraph (b) of this section, concurrent loan funds will be advanced in the following order: (1) 50 percent of the RUS insured loan funds; (2) 100 percent of...

  18. 30 CFR 57.11007 - Wooden components of ladders.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Wooden components of ladders. 57.11007 Section 57.11007 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... components of ladders shall not be painted except with a transparent finish. ...

  19. 20 CFR 219.57 - Evidence of a parent's support.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a parent's support. 219.57... EVIDENCE REQUIRED FOR PAYMENT Other Evidence Requirements § 219.57 Evidence of a parent's support. (a) The... Board will require other convincing evidence that the parent is receiving one-half of his or her support...

  20. 46 CFR 57.02-4 - Fabricator's responsibility.

    Science.gov (United States)

    2010-10-01

    ... in QW 480 and QB 480 of section IX, ASME Code, or on any other form acceptable to the Officer in... 46 Shipping 2 2010-10-01 2010-10-01 false Fabricator's responsibility. 57.02-4 Section 57.02-4 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) MARINE ENGINEERING WELDING AND BRAZING...

  1. 33 CFR 151.57 - Waste management plans.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Waste management plans. 151.57... Treaty as it Pertains to Pollution from Ships Garbage Pollution and Sewage § 151.57 Waste management... follows the plan. (c) Each waste management plan under paragraph (b) of this section must be in writing...

  2. 30 CFR 57.19096 - Familiarity with signal code.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Familiarity with signal code. 57.19096 Section... Hoisting Signaling § 57.19096 Familiarity with signal code. Any person reponsible for receiving or giving... with the posted signaling code. Shafts ...

  3. 36 CFR 261.57 - National Forest wilderness.

    Science.gov (United States)

    2010-07-01

    ...-burnable food or beverage containers, including deposit bottles, except for non-burnable containers... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false National Forest wilderness. 261.57 Section 261.57 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE...

  4. 30 CFR 57.4461 - Gasoline use restrictions underground.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Gasoline use restrictions underground. 57.4461... Prevention and Control Flammable and Combustible Liquids and Gases § 57.4461 Gasoline use restrictions underground. If gasoline is used underground to power internal combustion engines— (a) The mine shall be...

  5. 38 CFR 4.57 - Static foot deformities.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Static foot deformities. 4.57 Section 4.57 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS SCHEDULE... inversion and adduction. Exercise with undeveloped or unbalanced musculature, producing chronic irritation...

  6. 30 CFR 57.20011 - Barricades and warning signs.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Barricades and warning signs. 57.20011 Section... Miscellaneous § 57.20011 Barricades and warning signs. Areas where health or safety hazards exist that are not immediately obvious to employees shall be barricaded, or warning signs shall be posted at all approaches...

  7. 30 CFR 57.12011 - High-potential electrical conductors.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false High-potential electrical conductors. 57.12011... Electricity Surface and Underground § 57.12011 High-potential electrical conductors. High-potential electrical conductors shall be covered, insulated, or placed to prevent contact with low potential conductors. ...

  8. 30 CFR 57.12048 - Communication conductors on power poles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Communication conductors on power poles. 57... MINES Electricity Surface and Underground § 57.12048 Communication conductors on power poles. Telegraph, telephone, or signal wires shall not be installed on the same crossarm with power conductors. When carried...

  9. 30 CFR 57.16013 - Working with molten metal.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Working with molten metal. 57.16013 Section 57.16013 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Materials...

  10. 30 CFR 57.7003 - Drill area inspection.

    Science.gov (United States)

    2010-07-01

    ... inspected for hazards before starting the drilling operations. ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Drill area inspection. 57.7003 Section 57.7003... SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Drilling and Rotary...

  11. 30 CFR 57.19057 - Hoist operator's physical fitness.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Hoist operator's physical fitness. 57.19057... Hoisting Hoisting Procedures § 57.19057 Hoist operator's physical fitness. No person shall operate a hoist... who shall certify his fitness to perform this duty. Such certification shall be available at the mine. ...

  12. 40 CFR 98.57 - Records that must be retained.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Records that must be retained. 98.57... (CONTINUED) MANDATORY GREENHOUSE GAS REPORTING Adipic Acid Production § 98.57 Records that must be retained. In addition to the information required by § 98.3(g), you must retain the records specified in...

  13. 30 CFR 57.5039 - Maximum permissible concentration.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Maximum permissible concentration. 57.5039... Maximum permissible concentration. Except as provided by standard § 57.5005, persons shall not be exposed to air containing concentrations of radon daughters exceeding 1.0 WL in active workings. ...

  14. 30 CFR 57.7807 - Flushing the combustion chamber.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Flushing the combustion chamber. 57.7807... and Rotary Jet Piercing Rotary Jet Piercing-Surface Only § 57.7807 Flushing the combustion chamber. The combustion chamber of a jet drill stem which has been sitting unoperated in a drill hole shall be...

  15. 30 CFR 57.18002 - Examination of working places.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Examination of working places. 57.18002 Section... Programs Surface and Underground § 57.18002 Examination of working places. (a) A competent person designated by the operator shall examine each working place at least once each shift for conditions which may...

  16. 17 CFR 200.57 - Relationships with other members.

    Science.gov (United States)

    2010-04-01

    ... members. 200.57 Section 200.57 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION... other members. Each member should recognize that his conscience and those of other members are distinct... commission type of administration. However, a member should never permit his personal opinion so to conflict...

  17. 30 CFR 57.20020 - Unattended mine openings.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Unattended mine openings. 57.20020 Section 57.20020 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Miscellaneous...

  18. 30 CFR 57.20021 - Abandoned mine openings.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Abandoned mine openings. 57.20021 Section 57.20021 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Miscellaneous...

  19. 30 CFR 57.19079 - Blocking mine cars.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Blocking mine cars. 57.19079 Section 57.19079 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Personnel Hoisting...

  20. 19 CFR 145.57 - Regulations of other agencies.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 2 2010-04-01 2010-04-01 false Regulations of other agencies. 145.57 Section 145.57 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF... of other agencies. Certain types of plants and plant products, food, drugs, cosmetics, hazardous or...

  1. 30 CFR 57.4103 - Fueling internal combustion engines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fueling internal combustion engines. 57.4103... Prevention and Control Prohibitions/precautions/housekeeping § 57.4103 Fueling internal combustion engines. Internal combustion engines shall be switched off before refueling if the fuel tanks are integral parts of...

  2. 49 CFR 38.57 - Interior circulation, handrails and stanchions.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Interior circulation, handrails and stanchions. 38.57 Section 38.57 Transportation Office of the Secretary of Transportation AMERICANS WITH DISABILITIES ACT (ADA) ACCESSIBILITY SPECIFICATIONS FOR TRANSPORTATION VEHICLES Rapid Rail Vehicles and Systems...

  3. 30 CFR 57.14202 - Manual cleaning of conveyor pulleys.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Manual cleaning of conveyor pulleys. 57.14202... and Equipment Safety Practices and Operational Procedures § 57.14202 Manual cleaning of conveyor pulleys. Pulleys of conveyors shall not be cleaned manually while the conveyor is in motion. ...

  4. 30 CFR 57.4203 - Extinguisher recharging or replacement.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Extinguisher recharging or replacement. 57.4203... Prevention and Control Firefighting Equipment § 57.4203 Extinguisher recharging or replacement. Fire extinguishers shall be recharged or replaced with a fully charged extinguisher promptly after any discharge. ...

  5. 36 CFR 7.57 - Lake Meredith National Recreation Area.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Lake Meredith National Recreation Area. 7.57 Section 7.57 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF... Recreation Area. (a) The operation of motor vehicles within the Lake Meredith Recreation Area is prohibited...

  6. 33 CFR 159.57 - Installation, operation, and maintenance instructions.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Installation, operation, and maintenance instructions. 159.57 Section 159.57 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... number of persons that the device is capable of serving and the period of time the device is rated to...

  7. 40 CFR 52.57 - Control strategy: Sulfur oxides.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Control strategy: Sulfur oxides. 52.57... (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Alabama § 52.57 Control strategy: Sulfur oxides... for attainment and maintenance of the national standards for sulfur oxides in the vicinity of the...

  8. 49 CFR 229.57 - Foundation brake gear.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Foundation brake gear. 229.57 Section 229.57 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Foundation brake gear. A lever, rod, brake beam, hanger, or pin may not be worn through more than 30 percent...

  9. Behavioral profiles of three C57BL/6 substrains

    Directory of Open Access Journals (Sweden)

    Naoki Matsuo

    2010-06-01

    Full Text Available C57BL/6 inbred strains of mice are widely used in knockout and transgenic research. To evaluate the loss-of-function and gain-of-function effects of the gene of interest, animal behaviors are often examined. However, an issue of C57BL/6 substrains that is not always appreciated is that behaviors are known to be strongly influenced by genetic background. To investigate the behavioral characteristics of C57BL/6 substrains, we subjected C57BL/6J, C57BL/6N, and C57BL/6C mice to a behavior test battery. We performed both a regular-scale analysis, in which experimental conditions were tightly-controlled, and meta-analysis from large number of behavioral data that we have collected so far through the comprehensive behavioral test battery applied to 700-2,200 mice in total. Significant differences among the substrains were found in the results of various behavioral tests, including the open field, rotarod, elevated plus maze, prepulse inhibition, Porsolt forced swim, and spatial working memory version of the 8-arm radial maze. Our results show a divergence of behavioral performance in C57BL/6 substrains, which suggest that small genetic differences may have a great influence on behavioral phenotypes. Thus, the genetic background of different substrains should be carefully chosen, equated, and considered in the interpretation of mutant behavioral phenotypes.

  10. ASTM E57 3D imaging systems committee: an update

    Science.gov (United States)

    Cheok, Geraldine S.; Lytle, Alan M.; Saidi, Kamel S.

    2008-04-01

    In 2006, ASTM committee E57 was established to develop standards for the performance evaluation of 3D imaging systems. The committee's initial focus is on standards for 3D imaging systems typically used for applications including, but not limited to, construction and maintenance, surveying, mapping and terrain characterization, manufacturing (e.g., aerospace, shipbuilding), transportation, mining, mobility, historic preservation, and forensics. ASTM E57 consists of four subcommittees: Terminology, Test Methods, Best Practices, and Data Interoperability. This paper reports the accomplishments of the ASTM E57 3D Imaging Systems committee in 2007.

  11. Sample (S): SE57_S08 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available SE57_S08 Lotus japonicus (accessions B129 gifu and MG20 miyakojima) Lotus japonicus... NCBI taxonomy:34305 Lotus japonicus accessions were a gift from Dr. Toshio Aoki (Nihon University, Japan). ...

  12. Standardization of {sup 57}Co using different methods of LNMRI; Padronizacao do {sup 57}Co por diferentes metodos do LNMRI

    Energy Technology Data Exchange (ETDEWEB)

    Rezende, E.A.; Lopes, R.T., E-mail: eduarda.rezende@ifrj.edu.br [Coordenacao dos Programas de Pos-Graducacao em Engenharia (LIN/PEN/COPPE/UFRJ), Rio de Janeiro, RJ (Brazil); Silva, C.J. da; Poledna, R.; Silva, R.L. da; Tauhata, L. [Instituto de Radioprotecao e Dosimetria (IRD/CNEN-RJ/LNMRI), Rio de Janeiro, RJ (Brazil). Lab. Nacional de Metrologia das Radiacoes Ionizantes

    2015-07-01

    The activity of a {sup 57}Co solution was determined using four LNMRI different measurement methods. The solution was standardized by live-timed anti-coincidence method and sum-peak method. The efficiency curve and standard-sample comparison methods were also used in this comparison. The results and their measurement uncertainties demonstrating the equivalence of these methods. As an additional contribution, the gamma emission probabilities of {sup 57}Co were also determined. (author)

  13. After-Effects of the Cobalt-57-Iron-57 Electron-Capture Reaction in Hexacyanocobaltate (III) Complexes

    DEFF Research Database (Denmark)

    Fenger, Jørgen Folkvard; Siekierska, K.E.; Olsen, J.

    1973-01-01

    Isomorphous hexacyanocobaltate(III) complexes with the bivalent metal cations Mn2+, Fe2+, Co2+, Ni2+, Cu2+, Zn2+, and Cd2+ have been labelled with 57Co and used as Mössbauer sources. Whilst the spectrum of the complex Fe3[57Co(CN)6]2 can be resolved into a single line corresponding to the ion Fe II...

  14. Line shape of 57Co sources exhibiting self absorption

    Science.gov (United States)

    Spiering, H.; Ksenofontov, V.; Leupold, O.; Kusz, J.; Deák, L.; Németh, Z.; Bogdán, C.; Bottyán, L.; Nagy, D. L.

    2016-12-01

    The effect of selfabsorption in Mössbauer sources is studied in detail. Spectra were measured using an old 57 C o/ R h source of 74 M B q activity with an original activity of ca. 3.7 G B q and a 0.15 G B q 57 C o/ α - F e source magnetized by an in-plane magnetic field of 0.2 T. The 57 C o/ α - F e source of a thickness of 25 μ was used both from the active and the inactive side giving cause to very different selfabsorption effects. The absorber was a single crystal of ferrous ammonium sulphate hexahydrate (FAS). Its absorption properties were taken over from a detailed study (Bull et al., Hyperfine Interact. 94(1-3), 1; Spiering et al. 2). FAS (space group P21/c) crystallizes as flat plates containing the (overline {2}01) plane. The γ-direction was orthogonal to the crystal plate. The 57 C o atoms of the 57 C o/ R h source were assumed to be homogeneously distributed over a 6 μ thick Rh foil and to follow a one dimensional diffusion profile in the 25 μ Fe-foil. The diffusion length was fitted to 10 μ. The theory follows the Blume-Kistner equations for forward scattering (Blume and Kistner, Phys. Rev. 171, 417, 3) by integrating over the source sampled up to 128 layers.

  15. After-Effects of the Cobalt-57-Iron-57 Electron-Capture Reaction in Cobalt-57-Doped Tricadmium Bis [hexacyanoferrate (III)] Dodecahydrate

    DEFF Research Database (Denmark)

    Fenger, Jes; Frees, Lars A.

    1974-01-01

    Mössbauer-emission spectra of cobalt-57-doped Cd3[Fe(CN)6]2, 12H2O have been recorded at various temperatures and resolved into two doublets, one symmetric for the parent [Fe(CN)6]3– and one asymmetric attributed to a square-pyradimal [Fe(CN)5]2– complex. The asymmetry vanishes with increasing...

  16. 30 CFR 57.14213 - Ventilation and shielding for welding.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Ventilation and shielding for welding. 57.14213... welding. (a) Welding operations shall be shielded when performed at locations where arc flash could be hazardous to persons. (b) All welding operations shall be well-ventilated. ...

  17. 30 CFR 57.6802 - Bulk delivery vehicles.

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Explosives Maintenance-Surface and Underground § 57.6802 Bulk delivery vehicles. No welding or cutting shall be performed on a...

  18. 30 CFR 57.4601 - Oxygen cylinder storage.

    Science.gov (United States)

    2010-07-01

    ....4601 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Welding/cutting/compressed Gases § 57.4601 Oxygen cylinder storage. Oxygen cylinders shall...

  19. 30 CFR 57.4561 - Stationary diesel equipment underground.

    Science.gov (United States)

    2010-07-01

    ....4561 Section 57.4561 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES...) Provided with a thermal sensor that automatically stops the engine if overheating occurs. Welding/Cutting...

  20. 30 CFR 57.4602 - Gauges and regulators.

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Welding/cutting/compressed Gases § 57.4602 Gauges and regulators. Gauges and regulators used with...

  1. 30 CFR 57.4603 - Closure of valves.

    Science.gov (United States)

    2010-07-01

    ... Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Welding/cutting/compressed Gases § 57.4603 Closure of valves. To prevent accidental release of...

  2. 45 CFR 86.57 - Marital or parental status.

    Science.gov (United States)

    2010-10-01

    ... BASIS OF SEX IN EDUCATION PROGRAMS OR ACTIVITIES RECEIVING FEDERAL FINANCIAL ASSISTANCE Discrimination on the Basis of Sex in Employment in Education Programs or Activities Prohibited § 86.57 Marital or...) Concerning the potential marital, parental, or family status of an employee or applicant for employment which...

  3. 38 CFR 17.57 - Use of community nursing homes.

    Science.gov (United States)

    2010-07-01

    ... MEDICAL Use of Community Nursing Home Care Facilities § 17.57 Use of community nursing homes. (a) Nursing home care in a contract public or private nursing home facility may be authorized for the following... 38 Pensions, Bonuses, and Veterans' Relief 1 2010-07-01 2010-07-01 false Use of community nursing...

  4. 49 CFR 195.57 - Filing offshore pipeline condition reports.

    Science.gov (United States)

    2010-10-01

    ... TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Annual, Accident, and Safety-Related Condition Reporting § 195.57... inspected. (5) Length and date of installation of each exposed pipeline segment, and location; including, if... tract. (6) Length and date of installation of each pipeline segment, if different from a pipeline...

  5. Identification of Spinel Iron Oxide Nanoparticles by 57Fe NMR

    Directory of Open Access Journals (Sweden)

    SangGap Lee

    2011-12-01

    Full Text Available We have synthesized and studied monodisperse iron oxide nanoparticles of smaller than 10 nm to identify between the two spinel phases, magnetite and maghemite. It is shown that 57Fe NMR spectroscopy is a promising tool for distinguishing between the two phases.

  6. 33 CFR 5.57 - Traveling expenses and per diem.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Traveling expenses and per diem... GENERAL COAST GUARD AUXILIARY § 5.57 Traveling expenses and per diem. A member of the Auxiliary, when assigned to specific duties, may be paid actual necessary traveling expenses, including a per diem...

  7. 30 CFR 57.5046 - Protection against radon gas.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protection against radon gas. 57.5046 Section... Protection against radon gas. Where radon daughter concentrations exceed 10 WL, respirator protection against radon gas shall be provided in addition to protection against radon daughters. Protection against radon...

  8. A look back: 57 years of scientific computing

    DEFF Research Database (Denmark)

    Wasniewski, Jerzy

    2012-01-01

    This document outlines my 57-year career in computational mathematics, a career that took me from Poland to Canada and finally to Denmark. It of course spans a period in which both hardware and software developed enormously. Along the way I was fortunate to be faced with fascinating technical cha...

  9. 49 CFR 213.57 - Curves; elevation and speed limitations.

    Science.gov (United States)

    2010-10-01

    ... speed limitations. (a) The maximum crosslevel on the outside rail of a curve may not be more than 8...) and (d) on curves in Class 1 through 5 track which are contiguous to the high speed track provided... 49 Transportation 4 2010-10-01 2010-10-01 false Curves; elevation and speed limitations. 213.57...

  10. 49 CFR 173.57 - Acceptance criteria for new explosives.

    Science.gov (United States)

    2010-10-01

    ... appendix D to this part), a non-gelatin dynamite loses more than 3 percent by weight of the liquid explosive or a gelatin dynamite loses more than 10 percent by weight of the liquid explosive; or (3) During... 49 Transportation 2 2010-10-01 2010-10-01 false Acceptance criteria for new explosives. 173.57...

  11. 30 CFR 57.6602 - Static electricity dissipation during loading.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Static electricity dissipation during loading... MINES Explosives Extraneous Electricity-Surface and Underground § 57.6602 Static electricity dissipation... generates a static electricity hazard— (a) An evaluation of the potential static electricity hazard shall be...

  12. 27 CFR 478.57 - Discontinuance of business.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 3 2010-04-01 2010-04-01 false Discontinuance of business... Licenses § 478.57 Discontinuance of business. (a) Where a firearm or ammunition business is either discontinued or succeeded by a new owner, the owner of the business discontinued or succeeded shall within 30...

  13. Experimental Conditions: SE57_S06_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available for elucidating metabolite accumulation patterns in plants SE57_S06 Rye SE57_S06_M01 20 μ l aliquots contain...ysis of metabolite accumulation patterns Default SE57_SS01 Metabolic profiling ...

  14. Experimental Conditions: SE57_S04_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available for elucidating metabolite accumulation patterns in plants SE57_S04 Wheat SE57_S04_M01 20 μ l aliquots conta...alysis of metabolite accumulation patterns Default SE57_SS01 Metabolic profiling ...

  15. Experimental Conditions: SE57_S05_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available for elucidating metabolite accumulation patterns in plants SE57_S05 Oat SE57_S05_M01 20 μ l aliquots contain...ysis of metabolite accumulation patterns Default SE57_SS01 Metabolic profiling ...

  16. Designing 3D Structure by 5-7 Kirigami

    Science.gov (United States)

    Gong, Xingting; Cho, Yigil; Castle, Toen; Sussman, Daniel; Kamien, Randall

    2015-03-01

    The purpose of this talk is to explore how one can create 3D structures from 2D materials through the art of kirigami. Kirigami expands upon origami by allowing not only folds, but also cuts, into materials. If we take an incompressible material such as paper and remove a hole from it, the paper will buckle into the third dimension once that hole is sealed in order to relieve strain. Thus, orienting cuts and folds in certain places throughout a sheet of paper can influence its ``pop-up,'' 3D structure. To narrow down the inverse design problem, we confined ourselves to making only one kind of cut (which we call the ``5-7 cut'') on a honeycomb grid, and we show how this single cut can give rise to arbitrarily complex three dimensional structures. A simple set of rules exists: (a) one 5-7 cut divides the material into 2 sections which can choose to pop-up or down independently of each other, (b) rows of uniform cuts must pop up or down in unison, giving (nearly) arbitrary 2D structure, and (c) the 5-7 cuts can be arranged in various ways to create 6 basic pop-up ``modes,'' which can then be arranged to give (nearly) arbitrary 3D structure. These simple rules allow a framework for designing targeted 3D structure from an initial 2D sheet of material. This work was supported by NSF EFRI-ODISSEI Grant EFRI 13-31583.

  17. Effects of 5,7-dihydroxytriptamine (5,7-DHT on circadian locomotor activity of the blow fly, Calliphora vicina

    Directory of Open Access Journals (Sweden)

    Bronislaw Cymborowski

    2003-05-01

    Full Text Available The biogenic amine serotonin (5-HT is a neuromodulator in both vertebrates and invertebrates. It has been shown that serotonin, apart from its distinct effects on behavior, also plays a morphoregulatory role during the ontogeny of the insect's nervous system. The role of serotonin in modulating circadian locomotor activity of the blow fly, Calliphora vicina was explored. Injection of a specific neurotoxin, 5,7-dihydroxytryptamine (5,7-DHT, into the hemolymph appeared to significantly reduced the level of locomotor activity and lengthened the period (tau of circadian rhythmicity. After drug injection in constant darkness flies continued with their free-running rhythm of a locomotor activity, depending on the time of 5,7-DHT injection. This compound causes phase delay when administered in the early subjective day, and phase advance in the late subjective day. This effect is the opposite of the phase response curve obtained for 5-HT injections. This suggests that 5-HT might act as an entraining agent via the output pathway by feedback to clock neurons in the brain. Some of the injected insects regained their normal level of activity after a few days. These findings suggest a potential role for serotonin as modulator of circadian rhythms in insect including regulation of the level of locomotor activity.

  18. Experimental Conditions: SE57_S02_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available for elucidating metabolite accumulation patterns in plants SE57_S02 White mustard SE57_S02_M01 20 μ l aliquo...sis SE57_DS01 Analysis of metabolite accumulation patterns Default SE57_SS01 Metabolic profiling ...

  19. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to a combination of Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C and defence against vaginal pathogens (ID 934, further

    DEFF Research Database (Denmark)

    Tetens, Inge

    of Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C and defence against vaginal pathogens. The food constituent that is the subject of the claim, a combination of Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C, is sufficiently...... presented, the Panel concludes that a cause and effect relationship has not been established between the consumption of Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C and defence against vaginal pathogens....

  20. Geological Map of the Fredegonde (V-57) Quadrangle, Venus

    Science.gov (United States)

    Ivanov, M. A.; Head, J. W.

    2009-01-01

    The area of V-57, the Fredegonde quadrangle (50-75degS, 60-120degE, Fig.1), is located within the eastern portion of Lada Terra within the topographic province of midlands (0-2 km above MPR [1,2]). Midlands form the most abundant portion of the surface of Venus and are characterized by diverse sets of units and structures [3-11]. The area of the Fredegonde quadrangle is in contact with the elevated portion of Lada Terra to the W and with the lowland of Aino Planitia to the NE. The transitions of the mid-lands to the lowlands and highlands are, thus, one of the main themes of the geology within the V-57 quadrangle. The character of the transitions and distribution and sequence of units/structures in the midlands are crucially important in understanding the time and modes of formation of this topographic province. The most prominent features in the map area are linear deformational zones consisting of swarms of grooves and graben and large coronae. The zones characterize the central and NW portions of the map area and represent regionally important, broad (up to 100s km wide) ridges that are 100s m high. Relatively small (100s km across, 100s m deep) equidimensional basins occur between the corona-groove-chains in the west and border the central chain from the east. Here we describe units that make up the surface within the V-57 quadrangle and present a summary of our geological map that shows the areal distribution of the major groups of units.

  1. Study of yrast structures in {sup 55,57}Cr

    Energy Technology Data Exchange (ETDEWEB)

    Gupta, Anuradha, E-mail: annu1gupta1@gmail; Kumar, Amit, E-mail: akbcw2@gmail.com [Research Scholar, University of Jammu, Jammu-180006 (India); Singh, Suram, E-mail: suramsingh@gmail.com [Assistant Professor, Department of Physics, G.D.C. Kathua, 184101 (India); Bharti, Arun, E-mail: arunbharti-2003@yahoo.co.in [Professor, University of Jammu, Jammu-180006 (India)

    2016-05-06

    The characteristic nuclear structure properties of yrast bands of {sup 55,57}Cr have been investigated by using two body effective interactions incorporated in phenomenological axial framework. In order to check the validity of the chosen framework as well as chosen valence space, the calculated results are compared with the available experimental data and a good agreement has been found from the comparison. The back-bending in moment of inertia has also been studied and attributed to the alignment of odd g{sub 9/2} neutron along the rotation axis.

  2. Excitation functions of proton-induced reactions on natFe and enriched 57Fe with particular reference to the production of 57Co.

    Science.gov (United States)

    Al-Abyad, M; Comsan, M N H; Qaim, S M

    2009-01-01

    Excitation functions of the reactions (nat)Fe(p,xn)(55,56,57,58)Co, (nat)Fe(p,x)(51)Cr, (nat)Fe(p,x)(54)Mn, (57)Fe(p,n)(57)Co and (57)Fe(p,alpha)(54)Mn were measured from their respective thresholds up to 18.5MeV, with particular emphasis on data for the production of the radionuclide (57)Co (T(1/2)=271.8d). The conventional stacked-foil technique was used, and the samples for irradiation were prepared by an electroplating or sedimentation process. The measured excitation curves were compared with the data available in the literature as well as with results of nuclear model calculations. From the experimental data, the theoretical yields of the investigated radionuclides were calculated as a function of the proton energy. Over the energy range E(p)=15-->5MeV the calculated yield of (57)Co from the (57)Fe(p,n)(57)Co process amounts to 1.2MBq/microAh and from the (nat)Fe(p,xn)(57)Co reaction to 0.025MBq/microAh. The radionuclidic impurity levels are discussed. Use of highly enriched (57)Fe as target material would lead to formation of high-purity (57)Co.

  3. Psychiatric disorders in Danish children aged 5-7 years

    DEFF Research Database (Denmark)

    Elberling, Hanne; Linneberg, Allan; Ulrikka Rask, Charlotte

    2016-01-01

    from Danish national registries. RESULTS: The prevalence of any ICD-10 psychiatric disorder was 5.7% (95%CI: 4.4-7.1). Pervasive developmental disorders (PDD) were found in 1.3% (95%CI: 0.8-1.8) and behavioural and hyperkinetic disorders were found in 1.5% (95%CI: 0.9-2.1) and 1.0% (95%CI: 0.......4-1.6), respectively. Emotional disorders were found in 2.9% (95%CI: 1.9-40). More boys were diagnosed with PDD, behavioural disorders and tics. No gender differences were found in hyperactivity disorders (HD) and emotional disorders. Co-morbidity was frequent, in particular between HD and PDD, but also between HD...... and emotional disorder and behavioural disorder. Teenage mothers, single parents and low household income the first two years after the child's birth were associated with a three-to fourfold increased risk of psychiatric disorder in the child at age 5-7 years. CONCLUSION: The study results point to two "windows...

  4. STS-57 Earth observation of King Sound in northwest Australia

    Science.gov (United States)

    1993-01-01

    STS-57 Earth observation taken aboard Endeavour, Orbiter Vehicle (OV) 105, is of King Sound in northwest Australia. Roebuck Bay with the city of Broom on its northern shore is south of King Sound. Sediment in the sound is deposited by the Fitzroy River, which is the major body draining the Kimberley Plateau about 200 miles to the west. The extent of the tidal flats around the Sound is indicated by the large white areas covered with a salty residue. According to NASA scientists studying the STS-57 Earth photos, northwest wind gusts are ruffling areas of the water's surface at the mouth of King Sound and in neighboring Collier Bay. Therefore the water is less reflective and dark. The higher reflectance on the brightest areas is caused by biological oils floating on the surface and reducing the capillary wave action. The scientists point out that the oils take the forms of the currents and eddies in the picture. These eddies indicate that the water offshore is moving at a different speed

  5. Failure Investigation of WB-57 Aircraft Engine Cowling

    Science.gov (United States)

    Martinez, J. E.; Gafka, T.; Figert, J.

    2014-01-01

    The NASA Johnson Space Center (JSC) in Houston, Texas is the home of the NASA WB-57 High Altitude Research Program. Three fully operational WB-57 aircraft are based near JSC at Ellington Field. The aircraft have been flying research missions since the early 1960's, and continue to be an asset to the scientific community with professional, reliable, customer-oriented service designed to meet all scientific objectives. The NASA WB-57 Program provides unique, high-altitude airborne platforms to US Government agencies, academic institutions, and commercial customers in order to support scientific research and advanced technology development and testing at locations around the world. Mission examples include atmospheric and earth science, ground mapping, cosmic dust collection, rocket launch support, and test bed operations for future airborne or spaceborne systems. During the return from a 6 hour flight, at 30,000 feet, in the clean configuration, traveling at 175 knots indicated airspeed, in un-accelerated flight with the auto pilot engaged, in calm air, the 2-man crew heard a mechanical bang and felt a slight shudder followed by a few seconds of high frequency vibration. The crew did not notice any other abnormalities leading up to, or for the remaining 1 hour of flight and made an uneventful landing. Upon taxi into the chocks, the recovery ground crew noticed the high frequency long wire antenna had become disconnected from the vertical stabilizer and was trailing over the left inboard wing, and that the left engine upper center removable cowling panel was missing, with noticeable damage to the left engine inboard cowling fixed structure. The missing cowling panel was never recovered. Each engine cowling panel is attached to the engine nacelle using six bushings made of 17-4 PH steel. The cylinder portions of four of the six bushings were found still attached to the aircraft (Fig 1). The other two bushings were lost with the panel. The other four bushings exhibited

  6. Native signal peptide of human ERp57 disulfide isomerase mediates secretion of active native recombinant ERp57 protein in yeast Saccharomyces cerevisiae.

    Science.gov (United States)

    Čiplys, Evaldas; Žitkus, Eimantas; Slibinskas, Rimantas

    2013-06-01

    Human ERp57 protein is disulfide isomerase, facilitating proper folding of glycoprotein precursors in the concert with ER lectin chaperones calreticulin and calnexin. Growing amount of data also associates ERp57 with many different functions in subcellular locations outside the ER. Analysis of protein functions requires substantial amounts of correctly folded, biologically active protein, and in this study we introduce yeast Saccharomyces cerevisiae as a perfect host for production of human ERp57. Our data suggest that native signal peptide of human ERp57 protein is recognized and correctly processed in the yeast cells, which leads to protein secretion. Secreted recombinant ERp57 protein possesses native amino acid sequence and is biologically active. Moreover, secretion allows simple one-step purification of recombinant ERp57 protein with the yields reaching up to 10mg/L. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Potential protein post-translational modification in ERp57: A phenotype marker for male fertility

    OpenAIRE

    Viroj Wiwanitkit

    2010-01-01

    Background : In protein expression, post-translational modification is an important process. It is also an important process in human reproductive science. ERp57 is a molecule that is mentioned for post-translational modification. ERp57 is a component of human sperm acrosome proteins. However, the data on post-translational modifications of ERp57 is limited. Aim: The aim of this work is to assess potential protein post-translational modifications in ERp57 protein. Settings and Design : A desc...

  8. 40 CFR 204.57-7 - Acceptance and rejection of batch sequence.

    Science.gov (United States)

    2010-07-01

    ... sequence. 204.57-7 Section 204.57-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... § 204.57-7 Acceptance and rejection of batch sequence. (a) The manufacturer will continue to inspect consecutive batches until the batch sequence is accepted or rejected. The batch sequence will be accepted or...

  9. 42 CFR 57.311 - Cancellation of nursing student loans for disability or death.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Cancellation of nursing student loans for disability or death. 57.311 Section 57.311 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND..., SCHOLARSHIPS AND STUDENT LOANS Nursing Student Loans § 57.311 Cancellation of nursing student loans for...

  10. 50 CFR 221.57 - What is the standard of proof?

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false What is the standard of proof? 221.57 Section 221.57 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... Hearing, Briefing, and Decision § 221.57 What is the standard of proof? The standard of proof is a...

  11. 27 CFR 19.57 - Recovery and reuse of denatured spirits in manufacturing processes.

    Science.gov (United States)

    2010-04-01

    ... denatured spirits in manufacturing processes. 19.57 Section 19.57 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Administrative and Miscellaneous Provisions Activities Not Subject to This Part § 19.57 Recovery and reuse of...

  12. Experimental Conditions: SE57_S03_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available for elucidating metabolite accumulation patterns in plants SE57_S03 Black mustard SE57_S03_M01 20 μ l aliquo..._DS01 Analysis of metabolite accumulation patterns Default SE57_SS01 Metabolic profiling ...

  13. Experimental Conditions: SE57_S07_M01_D01 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available for elucidating metabolite accumulation patterns in plants SE57_S07 Durum wheat SE57_S07_M01 20 μ l aliquots...S01 Analysis of metabolite accumulation patterns Default SE57_SS01 Metabolic profiling ...

  14. 40 CFR 205.57-6 - Acceptance and rejection of batches.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Acceptance and rejection of batches. 205.57-6 Section 205.57-6 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-6...

  15. 40 CFR 205.57-5 - Reporting of the test results.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Reporting of the test results. 205.57-5 Section 205.57-5 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205.57-5...

  16. 40 CFR 205.57-9 - Prohibition on distribution in commerce; manufacturer's remedy.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Prohibition on distribution in commerce; manufacturer's remedy. 205.57-9 Section 205.57-9 Protection of Environment ENVIRONMENTAL... Medium and Heavy Trucks § 205.57-9 Prohibition on distribution in commerce; manufacturer's remedy. (a...

  17. Temperaturedependent After-Effects of the Cobalt-57-Iron-57 Electron-Capture Reaction in Cd3[57Co(CN)6]2,12H2O

    DEFF Research Database (Denmark)

    Fenger, Jes; Olsen, Jørgen

    1974-01-01

    The Mössbauer emission spectrum of Cd3[57Co(CN)6]2,12H2O was measured at temperatures between 78 and 323 K. Above 200 K the spectra can be resolved into two doublets; one is ascribed to 57Fe(CN)63– and one to 57Fe(CN)52–; it is suggested that the pentacyanide is formed by a Coulomb explosion...... following an Auger process associated with the 57Co(EC)57Fe-decay. Below 200 K a third species is detected; it may be Fe2+ formed by cyanide linkage isomerism. Measurements of the total intensity of the spectrum and the relative intensities of the individual doublets as a function of temperature permit...... in principle a determination of the f-factors for the species formed. It is estimated that the 57Fe(CN)52– has a formal Debye temperature of 170 K; at room temperature it is detected with a probability of only 50% of that of the 57Fe(CN)63–....

  18. Observational learning in C57BL/6j mice.

    Science.gov (United States)

    Carlier, Pascal; Jamon, Marc

    2006-11-01

    The ability of mice to solve a complex task by observational learning was investigated with C57BL/6j mice. Four female demonstrators were trained to reliably perform a sequence that consisted in pushing a piece of food into a tube attached to the side of a puzzle box, and recovering it by opening a drawer in front of the box. They then performed this sequence in front of naive mice assigned to individual cubicles in a box with a wire mesh front arranged in a row facing the demonstrators. A total of 25 naive mice (13 males and 12 females) were used. Fifteen mice observed 14 demonstrations a day for 5 days; 10 control mice were placed in similar cubicles, but behind a plastic screen which prevented them from observing the demonstrators. The mice were post-tested in the demonstrator situation, and 6 of 15 observers immediately reproduced the complete task successfully, but none of the naive or control mice were able to solve the task. The observers and controls were then subjected to a five level individual learning schedule. Observers learned the individual task significantly faster than the controls. No sex difference was found. These results suggest that observational learning processes at work were based on stimulus enhancement and observational conditioning.

  19. Transient Thermal Analyses of Passive Systems on SCEPTOR X-57

    Science.gov (United States)

    Chin, Jeffrey C.; Schnulo, Sydney L.; Smith, Andrew D.

    2017-01-01

    As efficiency, emissions, and noise become increasingly prominent considerations in aircraft design, turning to an electric propulsion system is a desirable solution. Achieving the intended benefits of distributed electric propulsion (DEP) requires thermally demanding high power systems, presenting a different set of challenges compared to traditional aircraft propulsion. The embedded nature of these heat sources often preclude the use of traditional thermal management systems in order to maximize performance, with less opportunity to exhaust waste heat to the surrounding environment. This paper summarizes the thermal analyses of X-57 vehicle subsystems that don't employ externally air-cooled heat sinks. The high-power battery, wires, high-lift motors, and aircraft outer surface are subjected to heat loads with stringent thermal constraints. The temperature of these components are tracked transiently, since they never reach a steady-state equilibrium. Through analysis and testing, this report demonstrates that properly characterizing the material properties is key to accurately modeling peak temperature of these systems, with less concern for spatial thermal gradients. Experimentally validated results show the thermal profile of these systems can be sufficiently estimated using reduced order approximations.

  20. Odorant-binding proteins OBP57d and OBP57e affect taste perception and host-plant preference in Drosophila sechellia.

    Directory of Open Access Journals (Sweden)

    Takashi Matsuo

    2007-05-01

    Full Text Available Despite its morphological similarity to the other species in the Drosophila melanogaster species complex, D. sechellia has evolved distinct physiological and behavioral adaptations to its host plant Morinda citrifolia, commonly known as Tahitian Noni. The odor of the ripe fruit of M. citrifolia originates from hexanoic and octanoic acid. D. sechellia is attracted to these two fatty acids, whereas the other species in the complex are repelled. Here, using interspecies hybrids between D. melanogaster deficiency mutants and D. sechellia, we showed that the Odorant-binding protein 57e (Obp57e gene is involved in the behavioral difference between the species. D. melanogaster knock-out flies for Obp57e and Obp57d showed altered behavioral responses to hexanoic acid and octanoic acid. Furthermore, the introduction of Obp57d and Obp57e from D. simulans and D. sechellia shifted the oviposition site preference of D. melanogaster Obp57d/e(KO flies to that of the original species, confirming the contribution of these genes to D. sechellia's specialization to M. citrifolia. Our finding of the genes involved in host-plant determination may lead to further understanding of mechanisms underlying taste perception, evolution of plant-herbivore interactions, and speciation.

  1. Potential protein post-translational modification in ERp57: A phenotype marker for male fertility

    Directory of Open Access Journals (Sweden)

    Viroj Wiwanitkit

    2010-01-01

    Full Text Available Background : In protein expression, post-translational modification is an important process. It is also an important process in human reproductive science. ERp57 is a molecule that is mentioned for post-translational modification. ERp57 is a component of human sperm acrosome proteins. However, the data on post-translational modifications of ERp57 is limited. Aim: The aim of this work is to assess potential protein post-translational modifications in ERp57 protein. Settings and Design : A descriptive computational bioinformatics study. Materials and Methods : In this work, potential protein post-translational modifications in ERp57 protein were assessed via a standard bioinformatics technique. Statistical Analysis Used : Bioinformatics analysis. Results : There are three post-translational modifications within ERp57 from bioinformatics analysis. Conclusion : This new knowledge can be useful for better realization on molecular process of male infertility.

  2. The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum.

    Science.gov (United States)

    Yang, Shuzhen; Zhou, Jie; Li, Dongmei; Shang, Chunyu; Peng, Litao; Pan, Siyi

    2017-06-01

    To evaluate the structure-activity relationship of 5,7-dihydroxyflavonoids against P. italicum, we tested the antifungal activity of 23 selected 5,7-dihydroxyflavonoids against spore germination of P. italicum, and the effects of hydroxyl group, hydrogenation, methylation and glycosylation on the antifungal activity are explored. C-4'-OH and C-3-OH are active groups for the 5,7-dihydroxyflavonoids against P. italicum. We find that hydrogenation of the C2/C3 bond decreases the antifungal activity of 5,7-dihydroxyflavonoids. Antifungal activity of 5,7-dihydroxyflavonoids against P. italicum was affected by the conjugation site of glycosylation and the class of sugar moiety. The correlation between antifungal activity and the inhibition of respiration of 5,7-dihydroxyflavonoids was further evaluated. We find no significant relationship among the IC50 of 5,7-dihydroxyflavonoids on spore germination and on respiration. Some 5,7-dihydroxyflavonoids even enhance the respiration of P. italicum. This indicate respiration is not the only target for 5,7-dihydroxyflavonoids against P. italicum. Copyright © 2016. Published by Elsevier Ltd.

  3. 30 CFR 57.16011 - Riding hoisted loads or on the hoist hook.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Riding hoisted loads or on the hoist hook. 57... MINES Materials Storage and Handling § 57.16011 Riding hoisted loads or on the hoist hook. Persons shall not ride on loads being moved by cranes or derricks, nor shall they ride the hoisting hooks unless...

  4. 42 CFR 57.313 - Loan cancellation for full-time employment as a registered nurse.

    Science.gov (United States)

    2010-10-01

    ... registered nurse. 57.313 Section 57.313 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN... nurse. (a) For loans made after November 18, 1971, and before September 29, 1979. A person who: (1... in full-time employment as a registered nurse (including teaching in any of the fields of nurse...

  5. 7 CFR 701.57 - Private non-industrial forest land.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Private non-industrial forest land. 701.57 Section 701... RELATED PROGRAMS PREVIOUSLY ADMINISTERED UNDER THIS PART § 701.57 Private non-industrial forest land. (a..., assistance made available under this section with respect to private, non-industrial forest land in an...

  6. 37 CFR 10.57 - Preservation of confidences and secrets of a client.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Preservation of confidences and secrets of a client. 10.57 Section 10.57 Patents, Trademarks, and Copyrights UNITED STATES PATENT... secret of a client for the advantage of the practitioner or of a third person, unless the client consents...

  7. 77 FR 13956 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-57; Small Entity Compliance Guide

    Science.gov (United States)

    2012-03-07

    ... Acquisition Regulation; Federal Acquisition Circular 2005-57; Small Entity Compliance Guide AGENCY: Department... Regulation (FAR). Interested parties may obtain further information regarding this rule by referring to FAC 2005-57, which precedes this document. These documents are also available via the Internet at http...

  8. 29 CFR 1960.57 - Training of safety and health inspectors.

    Science.gov (United States)

    2010-07-01

    ..., DEPARTMENT OF LABOR (CONTINUED) BASIC PROGRAM ELEMENTS FOR FEDERAL EMPLOYEE OCCUPATIONAL SAFETY AND HEALTH PROGRAMS AND RELATED MATTERS Training § 1960.57 Training of safety and health inspectors. Each agency shall... 29 Labor 9 2010-07-01 2010-07-01 false Training of safety and health inspectors. 1960.57 Section...

  9. 30 CFR 816.57 - Hydrologic balance: Activities in or adjacent to perennial or intermittent streams.

    Science.gov (United States)

    2010-07-01

    ... to perennial or intermittent streams. 816.57 Section 816.57 Mineral Resources OFFICE OF SURFACE... or adjacent to perennial or intermittent streams. (a)(1) Buffer requirement. Except as provided in..., measured horizontally, of a perennial or intermittent stream, unless the regulatory authority authorizes...

  10. 42 CFR 57.307 - Maximum amount of nursing student loans.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Maximum amount of nursing student loans. 57.307... Nursing Student Loans § 57.307 Maximum amount of nursing student loans. The total of the nursing student... longer than the 9-month academic year may be proportionately increased. The total of all nursing student...

  11. 82 FR 45861 - Classification and Requirements for Laser Illuminated Projectors (Laser Notice No. 57); Draft...

    Science.gov (United States)

    2017-10-02

    ...] Classification and Requirements for Laser Illuminated Projectors (Laser Notice No. 57); Draft Guidance for... the availability of the draft guidance entitled ``Classification and Requirements for Laser Illuminated Projectors (LIPs) (Laser Notice No. 57); Draft Guidance for Industry and Food and Drug...

  12. 7 CFR 57.960 - Small importations for consignee's personal use, display, or laboratory analysis.

    Science.gov (United States)

    2010-01-01

    ..., display, or laboratory analysis. Any eggs that are offered for importation, exclusively for the consignee's personal use, display, or laboratory analysis, and not for sale or distribution; which is sound..., display, or laboratory analysis. 57.960 Section 57.960 Agriculture Regulations of the Department of...

  13. 43 CFR 45.57 - What is the standard of proof?

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What is the standard of proof? 45.57 Section 45.57 Public Lands: Interior Office of the Secretary of the Interior CONDITIONS AND PRESCRIPTIONS... standard of proof? The standard of proof is a preponderance of the evidence. ...

  14. 46 CFR 57.02-2 - Adoption of section IX of the ASME Code.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section IX of the ASME Code. 57.02-2 Section... AND BRAZING General Requirements § 57.02-2 Adoption of section IX of the ASME Code. (a) The... accordance with section IX of the ASME (American Society of Mechanical Engineers) Code, as limited, modified...

  15. 30 CFR 57.12037 - Fuses in high-potential circuits.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Fuses in high-potential circuits. 57.12037... Electricity Surface and Underground § 57.12037 Fuses in high-potential circuits. Fuse tongs or hotline tools, shall be used when fuses are removed or replaced in high-potential circuits. ...

  16. 30 CFR 57.15006 - Protective equipment and clothing for hazards and irritants.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protective equipment and clothing for hazards and irritants. 57.15006 Section 57.15006 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION... clothing for hazards and irritants. Special protective equipment and special protective clothing shall be...

  17. 30 CFR 57.12010 - Isolation or insulation of communication conductors.

    Science.gov (United States)

    2010-07-01

    ... conductors. 57.12010 Section 57.12010 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF... conductors. Telephone and low-potential signal wire shall be protected, by isolation or suitable insulation, or both, from contacting energized power conductors or any other power source. ...

  18. 40 CFR 205.57-7 - Acceptance and rejection of batch sequence.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Acceptance and rejection of batch sequence. 205.57-7 Section 205.57-7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) NOISE ABATEMENT PROGRAMS TRANSPORTATION EQUIPMENT NOISE EMISSION CONTROLS Medium and Heavy Trucks § 205...

  19. 30 CFR 57.22313 - Explosion-protection systems (I-C mines).

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Explosion-protection systems (I-C mines). 57... MINES Safety Standards for Methane in Metal and Nonmetal Mines Equipment § 57.22313 Explosion-protection systems (I-C mines). Pressure-relief systems including vents, or explosion suppression systems, shall be...

  20. 30 CFR 57.14131 - Seat belts for surface haulage trucks.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Seat belts for surface haulage trucks. 57.14131 Section 57.14131 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND... trucks. (a) Seat belts shall be provided and worn in haulage trucks. (b) Seat belts shall be maintained...

  1. 30 CFR 57.12071 - Movement or operation of equipment near high-voltage powerlines.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Movement or operation of equipment near high-voltage powerlines. 57.12071 Section 57.12071 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION...-voltage powerlines. When equipment must be moved or operated near energized high-voltage powerlines (other...

  2. 30 CFR 57.16015 - Work or travel on overhead crane bridges.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Work or travel on overhead crane bridges. 57... MINES Materials Storage and Handling § 57.16015 Work or travel on overhead crane bridges. No person shall work from or travel on the bridge of an overhead crane unless the bridge is provided with...

  3. 32 CFR Appendix F to Part 57 - Parent and Student Rights

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Parent and Student Rights F Appendix F to Part 57 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE PERSONNEL, MILITARY AND..., App. F Appendix F to Part 57—Parent and Student Rights A. Parental Consent (1) The consent of a parent...

  4. 30 CFR 57.6131 - Location of explosive material storage facilities.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Location of explosive material storage facilities. 57.6131 Section 57.6131 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Explosives Storage-Surface Only §...

  5. 30 CFR 57.20014 - Prohibited areas for food and beverages.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Prohibited areas for food and beverages. 57... MINES Miscellaneous § 57.20014 Prohibited areas for food and beverages. No person shall be allowed to consume or store food or beverages in a toilet room or in any area exposed to a toxic material. ...

  6. Data of evolutionary structure change: 1I57A-2QEPA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1I57A-2QEPA 1I57 2QEP A A -EMEKEF-EQIDKS----GSWAAIYQDIRHEASDF--PCRVAKLPKNKNRNRYRDV...2QEP A 2QEPA AYQAEPNSSFVA...2QEP A 2QEPA RVLLKAENSHSHSD...2QEP A 2QEPA DHDPRNPAYIA ...2QEP A 2QEPA VSEHIWCEDFL

  7. 17 CFR 1.57 - Operations and activities of introducing brokers.

    Science.gov (United States)

    2010-04-01

    ... introducing brokers. 1.57 Section 1.57 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION... introducing brokers. (a) Each introducing broker must: (1) Open and carry each customer's and option customer..., That an introducing broker which has entered into a guarantee agreement with a futures commission...

  8. In situ gel-forming AP-57 peptide delivery system for cutaneous wound healing.

    Science.gov (United States)

    Li, Xiaoling; Fan, Rangrang; Tong, Aiping; Yang, Meijia; Deng, Jiaojiao; Zhou, Liangxue; Zhang, Xiaoning; Guo, Gang

    2015-11-10

    In situ gel-forming system as local drug delivery system in dermal traumas has generated a great interest. Accumulating evidence shows that antimicrobial peptides play pivotal roles in the process of wound healing. Here in this study, to explore the potential application of antimicrobial peptide in wound healing, biodegradable poly(L-lactic acid)-Pluronic L35-poly(L-lactic acid) (PLLA-L35-PLLA) was developed at first. Then based on this polymer, an injectable in situ gel-forming system composed of human antimicrobial peptides 57 (AP-57) loaded nanoparticles and thermosensitive hydrogel was prepared and applied for cutaneous wound healing. AP-57 peptides were enclosed with biocompatible nanoparticles (AP-57-NPs) with high drug loading and encapsulation efficiency. AP-57-NPs were further encapsulated in a thermosensitive hydrogel (AP-57-NPs-H) to facilitate its application in cutaneous wound repair. As a result, AP-57-NPs-H released AP-57 in an extended period and exhibited quite low cytotoxicity and high anti-oxidant activity in vitro. Moreover, AP-57-NPs-H was free-flowing liquid at room temperature, and can form non-flowing gel without any crosslink agent upon applied on the wounds. In vivo wound healing assay using full-thickness dermal defect model of SD rats indicated that AP-57-NPs-H could significantly promote wound healing. At day 14 after operation, AP-57-NPs-H treated group showed nearly complete wound closure of 96.78 ± 3.12%, whereas NS, NPs-H and AP-57-NPs group recovered by about 68.78 ± 4.93%, 81.96 ± 3.26% and 87.80 ± 4.62%, respectively. Histopathological examination suggested that AP-57-NPs-H could promote cutaneous wound healing through enhancing granulation tissue formation, increasing collagen deposition and promoting angiogenesis in the wound tissue. Therefore, AP-57-NPs-H might have potential application in wound healing. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Strong far-infrared cooling lines, peculiar CO kinematics, and possible star-formation suppression in Hickson compact group 57

    DEFF Research Database (Denmark)

    Alatalo, K.; Appleton, P. N.; Lisenfeld, U.

    2014-01-01

    We present [C II] and [O I] observations from Herschel and CO(1-0) maps from the Combined Array for Research in Millimeter Astronomy (CARMA) of the Hickson compact group HCG 57, focusing on the galaxies HCG 57a and HCG 57d. HCG 57a has been previously shown to contain enhanced quantities of warm ...

  10. Antigenic and functional characterization of p57 produced by Renibacterium salmoninarum

    Science.gov (United States)

    Weins, G.; Chien, M.S.; Winton, J.R.; Kaatari, S.L.

    1999-01-01

    Renibacterium salmoninarum, the causative agent of bacterial kidney disease, produces large quantities of a 57-58 kDa protein (p57) during growth in broth culture and during infection of salmonid fish. Biological activities of secreted p57 include agglutination of salrnonid leucocytes and rabbit erythrocytes. We define the location of epitopes on p57 recognized by agglutination-blocking monoclonal antibodies (MAbs) 4Cl1, 4H8 and 4D3, and demonstrate that the majority of secreted p57 is a nlonomer that retains salrnonid leucocyte agglutinat~ng activity. The 3 MAbs bound a recombinant, amino-terminal fragment of p57 (211 aa) but not a carboxy-terminal fragment (315 aa) demonstrating that the neutralizing epitopes are located within the amino-terminal portion of p57. When combinations of the MAbs were used in an antigen capture ELISA. the epitopes recognized by the 3 MAbs were shown to be sterically separate. However, when the same MAb was used as both the coating and detection MAb, binding of the biotinylated detection MAb was not observed. These data indicate that the epitopes recognized by the 3 agglutination-blocking antibodies are functionally available only once per molecule and that native p57 exists as a monomer Similar ELISA results were obtained when kidney tissues from 3 naturally infected chinook salmon were assayed. Finally, a p57 monomer was purified using anion exchange and size exclusion chromatography that retained in vitro agglutinating activity. A model in which p57 is released from R. salmoninarum as a biologically active monomer during infection of salmonid fish is proposed.

  11. Cellular Response upon Stress: p57 Contribution to the Final Outcome

    Directory of Open Access Journals (Sweden)

    Marianna Nicoletta Rossi

    2015-01-01

    Full Text Available Progression through the cell cycle is one of the most important decisions during the life of a cell and several kinds of stress are able to influence this choice. p57 is a cyclin-dependent kinase inhibitor belonging to the CIP/KIP family and is a well-known regulator of the cell cycle during embryogenesis and tissue differentiation. p57 loss has been reported in a variety of cancers and great effort has been spent during the past years studying the mechanisms of p57 regulation and the effects of p57 reexpression on tumor growth. Recently, growing amount of evidence points out that p57 has a specific function in cell cycle regulation upon cellular stress that is only partially shared by the other CIP/KIP inhibitors p21 and p27. Furthermore, it is nowadays emerging that p57 plays a role in the induction of apoptosis and senescence after cellular stress independently of its cell cycle related functions. This review focuses on the contribution that p57 holds in regulating cell cycle arrest, apoptosis, and senescence after cellular stress with particular attention to the response of cancer cells.

  12. Comparative study of the immunological characteristics of three different C57BL/6N mouse substrains.

    Science.gov (United States)

    Choi, Jun Young; Kim, Hye Ryeong; Kim, Kil Soo; Jung, Young-Suk; Cho, Joon Young; Hwang, Dae Youn; Song, Hyun Keun

    2017-06-01

    Inbred mice, a systematically developed homogeneous animal, have been developed to maintain experimental reproducibility and to minimize experimental variables in animal-based studies. In particular, C57BL/6 mice are frequently used in experiments into immunology and antitumor activity experiments. This study was compared the immunological characteristics of C57BL/6NKorl, a Korean developed experimental animal resource, with those of two other C57BL/6N substrains. Mouse body, thymus, and spleen weights in C57BL/6NKorl were not significantly different from those of the other two C57BL/6N substrains. Among the three substrains, there was no difference in the distribution of T and B cells, which are lymphocytes involved in adaptive immunity, and no difference in NK cells related to innate immunity. Results for macrophages and granulocytes, which have roles in innate immunity, were similar in all three substrains. In order to investigate the expressions of major histocompatibility complex (MHC) molecules and allogenic antigens, splenocytes were separated from obtained spleen and analyzed by using flow cytometry. MHC class I and II molecules, which are important during self/non-self-discrimination, were similar in the three substrains. In addition, expression of alloantigen involved in allografts showed similar results in the three substrain. Thus, the results of this study provide strong evidence that C57BL/6NKorl is immunologically similar to two other C57BL/6N substrains.

  13. Oriented Scintillation Spectrometer Experiment observations of Co-57 in SN 1987A

    Science.gov (United States)

    Kurfess, J. D.; Johnson, W. N.; Kinzer, R. L.; Kroeger, R. A.; Strickman, M. S.; Grove, J. E.; Leising, M. D.; Clayton, D. D.; Grabelsky, D. A.; Purcell, W. R.

    1992-01-01

    The Oriented Scintillation Spectrometer Experiment (OSSE) on the Compton Gamma Ray Observatory has observed SN 1987A for two 2 week periods during the first 9 months of the mission. Evidence for gamma-ray line and continuum emission from Co-57 is observed with an intensity of about 10 exp -4 gamma/sq cm/s. This photon flux between 50 and 136 keV is demonstrated by Monte Carlo calculations to be independent of the radial distribution of Co-57 for models of low optical depth, viz., models having photoelectric absorption losses of 122 keV photons no greater than several percent. For such models the observed Co-57 flux indicates that the ratio Ni-57/Ni-56 produced in the explosion was about 1.5 times the solar system ratio of Fe-57/Fe-56. When compared with nearly contemporaneous bolometric estimates of the luminosity for SN 1987A, our observations imply that Co-57 radioactivity does not account for most of the current luminosity of the supernova remnant in low optical depth models. We suggest alternatives, including a large optical depth model that is able to provide the SN 1987A luminosity and is consistent with the OSSE flux. It requires a 57/56 production ratio about twice solar.

  14. Experience in staging testis tumors with bleomycin cobalt 57 and present role of gallium 67 scan

    Energy Technology Data Exchange (ETDEWEB)

    Mukerjee, M.G.; Mittemeyer, B.T.

    1976-10-01

    A technique was developed using bleomycin and cobalt 57 to study nodal metastases in testis tumors. Comparative studies were made on 15 cases with gallium 67, lymphangiography, supraclavicular node biopsy, liver and spleen scans, chest x-ray, excretory urogram, bone survey and pathological study of surgical specimens when possible. The results with the bleomycin-cobalt 57 complex and gallium 67 were discouraging. The bleomycin-cobalt 57 study was discontinued. Pathological staging is still the most accurate of all modalities available for staging testicular malignancies.

  15. Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).

    Science.gov (United States)

    Otto, Gordon P; Rathkolb, Birgit; Oestereicher, Manuela A; Lengger, Christoph J; Moerth, Corinna; Micklich, Kateryna; Fuchs, Helmut; Gailus-Durner, Valérie; Wolf, Eckhard; Hrabě de Angelis, Martin

    2016-01-01

    Although various mouse inbred strains are widely used to investigate disease mechanisms and to establish new therapeutic strategies, sex-specific reference intervals for laboratory diagnostic analytes that are generated from large numbers of animals have been unavailable. In this retrospective study, we screened data from more than 12,000 mice phenotyped in the German Mouse Clinic from January 2006 through June 2014 and selected animals with the genetic background of C57BL/6J, C57BL/6N, or C3HeB/FeJ. In addition, we distinguished between the C57BL/6NTac substrain and C57BL/6N mice received from other vendors. The corresponding data sets of electrolytes (sodium, potassium, calcium, chloride, inorganic phosphate), lipids (cholesterol, triglyceride), and enzyme activities (ALT, AST, ALP, α-amylase) and urea, albumin, and total protein levels were analyzed. Significant effects of age and sex on these analytes were identified, and strain- or substrain- and sex-specific reference intervals for 90- to 135-d-old mice were calculated. In addition, we include an overview of the literature that reports clinical chemistry values for wild-type mice of different strains. Our results support researchers interpreting clinical chemistry values from various mouse mutants and corresponding wild-type controls based on the examined strains and substrains.

  16. {sup 57}Fe Emission Mössbauer Study on Gd{sub 3}Ga{sub 5}O{sub 12} implanted with dilute{sup 57}Mn

    Energy Technology Data Exchange (ETDEWEB)

    Krastev, P. B. [Bulgarian Academy of Sciences, Institute for Nuclear Research and Nuclear Energy (Bulgaria); Gunnlaugsson, H. P., E-mail: haraldur.p.gunnlaugsson@cern.ch [CERN (Switzerland); Nomura, K. [Tokyo University of Science (Japan); Adoons, V. [University of Zululand, Physics and Engineering Department (South Africa); Gerami, A. M.; Johnston, K. [CERN (Switzerland); Ncube, M. [University of the Witwatersrand, School of Physics (South Africa); Mantovan, R. [IMM-CNR, Laboratorio MDM (Italy); Masenda, H. [University of the Witwatersrand, School of Physics (South Africa); Matveyev, Y. A. [Moscow Institute of Physics and Technology (Russian Federation); Mølholt, T. E. [CERN (Switzerland); Unzueta, I. [Euskal Herriko Unibertsitatea (UPV/EHU), BCMaterials & Elektrizitate eta Elektronika Saila (Spain); Bharuth-Ram, K. [Durban University of Technology, Physics Department (South Africa); Gislason, H. [University of Iceland, Science Institute (Iceland); Langouche, G. [University of Leuven, Instituut voor Kern- en Stralingsfysika (Belgium); Naidoo, D. [University of the Witwatersrand, School of Physics (South Africa); Ólafsson, S. [University of Iceland, Science Institute (Iceland); Collaboration: the ISOLDE collaboration

    2016-12-15

    {sup 57}Fe emission Mössbauer spectroscopy has been applied to study the lattice location and properties of Fe in gadolinium gallium garnet Gd{sub 3}Ga{sub 5}O{sub 12} (GGG) single crystals in the temperature interval 300 – 563 K within the extremely dilute (<10{sup −4} at.%) regime following the implantation of{sup 57}Mn (T{sup 1}{sub /2}= 1.5 min.) at ISOLDE/CERN. These results are compared with earlier Mössbauer spectroscopy study of Fe-doped gadolinium gallium garnet Gd{sub 3}Ga{sub 5}O{sub 12}(GGG), with implantation fluences between 8×10{sup 15} and 6×10{sup 16} atoms cm{sup −2}. Three Fe components are observed in the emission Mössbauer spectra: (i) high spin Fe{sup 2+} located at damage sites due to the implantation process, (ii) high spin Fe{sup 3+} at substitutional tetrahedral Ga sites, and (iii) interstitial Fe, probably due to the recoil imparted on the daughter{sup 57∗}Fe nucleus in the β{sup −} decay of{sup 57}Mn. In contrast to high fluence{sup 57}Fe implantation studies the Fe{sup 3+} ions are found to prefer the tetrahedral Ga site over the octahedral Ga site. No annealing stages are evident in the temperature range investigated. Despite the very low concentration, high-spin Fe{sup 3+} shows fast spin relaxation, presumably due to an indirect interaction between nearby gadolinium atoms.

  17. 29 CFR 1915.57 - Uses of fissionable material in ship repairing and shipbuilding.

    Science.gov (United States)

    2010-07-01

    ... HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) OCCUPATIONAL SAFETY AND HEALTH STANDARDS FOR SHIPYARD EMPLOYMENT Welding, Cutting and Heating § 1915.57 Uses of fissionable material in ship repairing...

  18. PATHOGENESIS OF METHANOL-INDUCED CRANIOFACIAL DEFECTS IN C57BL/6J MICE

    Science.gov (United States)

    BACKGROUND: Methanol administered to C57BL/6J mice during gastrulation causes severe craniofacial dysmorphology. We describe dysmorphogenesis, cell death, cell cycle assessment, and effects on development of cranial ganglia and nerves observed following administration of methanol...

  19. Investigating the Role of p57Kip2 in Prostate Cancer

    National Research Council Canada - National Science Library

    Jin, Ren J

    2005-01-01

    .... When virus-mediated overexpression of p57Kip2 in prostate cancer cells (LNCaP), significantly suppressed the cells motility, potential for invasion, arrested the cell cycles at G0/G1 stage, and induced apoptosis...

  20. 30 CFR 57.22106 - Dust containing volatile matter (I-C mines).

    Science.gov (United States)

    2010-07-01

    ... MINES Safety Standards for Methane in Metal and Nonmetal Mines Fire Prevention and Control § 57.22106..., if suspended in air, would become an explosive mixture. An explosive mixture of dust containing...

  1. 30 CFR 57.6404 - Separation of blasting circuits from power source.

    Science.gov (United States)

    2010-07-01

    ... NONMETAL MINES Explosives Electric Blasting-Surface and Underground § 57.6404 Separation of blasting... locked in the open position except when closed to fire the blast. (b) Lead wires shall not be connected...

  2. 57. Baltisches Historikertreffen : vom 5. bis 6. Juni 2004 in Göttingen

    Index Scriptorium Estoniae

    2004-01-01

    57. balti ajaloolaste kohtumisel 5.-6. juunini 2004 esinesid ettekannetega Erki Tammiksaar, Tiit Rosenberg, Olaf Mertelsmann, Klaus Neitmann, Matthias Thumsen, Ilgvars Misans, Henrik Bolte, Thomas Brück, Juhan Kreem, Dieter Heckmann, Stefan Hartmann. Ettekannete kokkuvõtted

  3. Brain plasticity and cognitive functions after ethanol consumption in C57BL/6J mice

    National Research Council Canada - National Science Library

    Stragier, E; Martin, V; Davenas, E; Poilbout, C; Mongeau, R; Corradetti, R; Lanfumey, L

    2015-01-01

    .... However, we recently reported that chronic and moderate ethanol intake in C57BL/6J mice induced chromatin remodeling within the Bdnf promoters, leading to both enhanced brain-derived neurotrophic factor (BDNF...

  4. Caracterizacion del desarrollo y absorcion de nutrimentos del hibrido de maiz HC-57

    National Research Council Canada - National Science Library

    Fallas, Roger; Bertsch, Floria; Echandi, Carlos; Henriquez, Carlos

    2011-01-01

    En la Estacion Experimental Agricola Fabio Baudrit Moreno, Alajuela, Costa Rica se realizo un ensayo con el objetivo de determinar la absorcion de nutrimentos por parte del hibrido comercial de maiz HC-57...

  5. High fat feeding unmasks variable insulin responses in male C57BL/6 mouse substrains.

    Science.gov (United States)

    Hull, Rebecca L; Willard, Joshua R; Struck, Matthias D; Barrow, Breanne M; Brar, Gurkirat S; Andrikopoulos, Sofianos; Zraika, Sakeneh

    2017-04-01

    Mouse models are widely used for elucidating mechanisms underlying type 2 diabetes. Genetic background profoundly affects metabolic phenotype; therefore, selecting the appropriate model is critical. Although variability in metabolic responses between mouse strains is now well recognized, it also occurs within C57BL/6 mice, of which several substrains exist. This within-strain variability is poorly understood and could emanate from genetic and/or environmental differences. To better define the within-strain variability, we performed the first comprehensive comparison of insulin secretion from C57BL/6 substrains 6J, 6JWehi, 6NJ, 6NHsd, 6NTac and 6NCrl. In vitro, glucose-stimulated insulin secretion correlated with Nnt mutation status, wherein responses were uniformly lower in islets from C57BL/6J vs C57BL/6N mice. In contrast, in vivo insulin responses after 18 weeks of low fat feeding showed no differences among any of the six substrains. When challenged with a high-fat diet for 18 weeks, C57BL/6J substrains responded with a similar increase in insulin release. However, variability was evident among C57BL/6N substrains. Strikingly, 6NJ mice showed no increase in insulin release after high fat feeding, contributing to the ensuing hyperglycemia. The variability in insulin responses among high-fat-fed C57BL/6N mice could not be explained by differences in insulin sensitivity, body weight, food intake or beta-cell area. Rather, as yet unidentified genetic and/or environmental factor(s) are likely contributors. Together, our findings emphasize that caution should be exercised in extrapolating data from in vitro studies to the in vivo situation and inform on selecting the appropriate C57BL/6 substrain for metabolic studies. © 2017 Society for Endocrinology.

  6. Expression of connexin 57 in the olfactory epithelium and olfactory bulb.

    Science.gov (United States)

    Zhang, Chunbo

    2011-11-01

    In the visual system, deletion of connexin 57 (Cx57) reduces gap junction coupling among horizontal cells and results in smaller receptive fields. To explore potential functions of Cx57 in olfaction, in situ hybridization and immunohistochemistry methods were used to investigate expression of Cx57 in the olfactory epithelium and olfactory bulb. Hybridization signal was stronger in the olfactory epithelial layer compared to the connective tissue underneath. Within the sensory epithelial layer, hybridization signal was visible in sublayers containing cell bodies of basal cells and olfactory neurons but not evident at the apical sublayer comprising cell bodies of sustentacular cells. These Cx57 positive cells were clustered into small groups to form different patterns in the olfactory epithelium. However, individual patterns did not associate with specific regions of olfactory turbinates or specific olfactory receptor zones. Patched distribution of hybridization positive cells was also observed in the olfactory bulb and accessory olfactory bulb in layers where granule cells, mitral cells, and juxtaglomerular cells reside. Immunostaining was observed in the cell types described above but the intensity was weaker than that in the retina. This study has provided anatomical basis for future studies on the function of Cx57 in the olfactory system. Copyright © 2011 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

  7. 57 | Page

    African Journals Online (AJOL)

    Fr. Ikenga

    genocide, and hijacking (air piracy)28. Although universal jurisdiction may seem naturally extendable in the future to Internet piracy, such as computer hacking and viruses, such an extension is unlikely given the traditional tortoise-like development of universal jurisdiction. Just as important as it is, universal jurisdiction ...

  8. P57

    Directory of Open Access Journals (Sweden)

    A. Belkovets

    2015-11-01

    Conclusion: As a first step in the development of GC riskometry was found that noninvasive set of serological biomarkers is an informative and non-expensive tool for the early detection of GC in population-based retrospective cohort survey in Siberian population. Low levels of PGI and PGI/PGII ratio were proven as the most valuable prognostic factors. The low level of G-17 as a single index did not significantly predict the risk of GC.

  9. The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules

    DEFF Research Database (Denmark)

    Quarsten, H; Paulsen, G; Johansen, B H

    1998-01-01

    -predisposing class II molecules. The molecular explanation for such a phenomenon could be that class II beta chains with Aspbeta57 form a salt bridge between Aspbeta57 and a conserved Arg of the a chain, whereas in non-Aspbeta57 molecules the Arg is unopposed and free to interact with negatively charged P9 peptide...

  10. KSHV inhibits stress granule formation by viral ORF57 blocking PKR activation.

    Directory of Open Access Journals (Sweden)

    Nishi R Sharma

    2017-10-01

    Full Text Available TIA-1 positive stress granules (SG represent the storage sites of stalled mRNAs and are often associated with the cellular antiviral response. In this report, we provide evidence that Kaposi's sarcoma-associated herpesvirus (KSHV overcomes the host antiviral response by inhibition of SG formation via a viral lytic protein ORF57. By immunofluorescence analysis, we found that B lymphocytes with KSHV lytic infection are refractory to SG induction. KSHV ORF57, an essential post-transcriptional regulator of viral gene expression and the production of new viral progeny, inhibits SG formation induced experimentally by arsenite and poly I:C, but not by heat stress. KSHV ORF37 (vSOX bearing intrinsic endoribonuclease activity also inhibits arsenite-induced SG formation, but KSHV RTA, vIRF-2, ORF45, ORF59 and LANA exert no such function. ORF57 binds both PKR-activating protein (PACT and protein kinase R (PKR through their RNA-binding motifs and prevents PACT-PKR interaction in the PKR pathway which inhibits KSHV production. Consistently, knocking down PKR expression significantly promotes KSHV virion production. ORF57 interacts with PKR to inhibit PKR binding dsRNA and its autophosphorylation, leading to inhibition of eIF2α phosphorylation and SG formation. Homologous protein HSV-1 ICP27, but not EBV EB2, resembles KSHV ORF57 in the ability to block the PKR/eIF2α/SG pathway. In addition, KSHV ORF57 inhibits poly I:C-induced TLR3 phosphorylation. Altogether, our data provide the first evidence that KSHV ORF57 plays a role in modulating PKR/eIF2α/SG axis and enhances virus production during virus lytic infection.

  11. 30 CFR 57.4660 - Work in shafts, raises, or winzes and other activities involving hazard areas.

    Science.gov (United States)

    2010-07-01

    ... activities involving hazard areas. 57.4660 Section 57.4660 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Fire Prevention and Control Welding/cutting/compressed Gases § 57.4660...

  12. 36 CFR 51.57 - How does a concessioner request arbitration of the construction cost of a capital improvement?

    Science.gov (United States)

    2010-07-01

    ... request arbitration of the construction cost of a capital improvement? 51.57 Section 51.57 Parks, Forests... Surrender Interest § 51.57 How does a concessioner request arbitration of the construction cost of a capital improvement? If a concessioner requests arbitration of the construction cost of a capital improvement...

  13. Hypolipidemic effect of young persimmon fruit in C57BL/6.KOR-ApoEshl mice.

    Science.gov (United States)

    Matsumoto, Kenji; Yokoyama, Shin-ichiro; Gato, Nobuki

    2008-10-01

    We investigated the hypolipidemic effects of young persimmon fruit (YP) on apolipoprotein E-deficient C57BL/6.KOR-ApoEshl mice. These mice exhibited higher plasma cholesterols, except for high-density lipoprotein (HDL), and lower plasma HDL cholesterol than C57BL/6.Cr mice that had the same genetic background as the C57BL/6.KOR-ApoEshl mice. Male C57BL/6.KOR-ApoEshl mice (n=5) were fed a diet supplemented with dry YP, Hachiya-kaki, at a concentration of 5% (w/w) for 10 weeks. YP treatment significantly lowered plasma chylomicron, very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) cholesterols, and triglyceride, and this response was accompanied by an elevation of fecal bile acid excretion. In the liver, sterol regulatory element binding protein-2 gene expression was significantly higher in mice fed YP, while the mRNA and protein levels of the LDL receptor did not change. These results indicate that acceleration of fecal bile acid excretion is a major mechanism of the hypolipidemic effect induced by YP in C57BL/6.KOR-ApoEshl mice.

  14. Application of emission ( 57Co) Mössbauer spectroscopy in bioscience

    Science.gov (United States)

    Kamnev, Alexander A.

    2005-06-01

    Cobalt is an essential trace element with a broad range of physiological and biochemical functions. However, biochemical speciation of cobalt and structural investigations of cobalt-containing complexes with biomacromolecules are challenging, as the participation of cobalt in physiological processes is limited by its very low concentrations. Emission Mössbauer spectroscopy (EMS), with the radioactive 57Co isotope as the most widely used nuclide, is several orders of magnitude more sensitive than its 57Fe absorption variant which has had a rich history of applications in bioscience. Nevertheless, owing to specific difficulties related to the necessity of using radioactive 57Co in samples under study, applications of EMS in biological fields have so far been sparse. In this communication, the EMS applicability to studying biological objects as well as some specific aspects of the EMS methodology are considered in order to draw attention to the unique structural information which can be obtained non-destructively in situ. Chemical consequences (after-effects) of the nuclear transition ( 57Co→ 57Fe), which provide additional information on the electron acceptor properties of the proximate chemical microenvironment of the metal ions, are also considered. The data presented demonstrate that EMS is a sensitive tool for monitoring the chemical state and coordination of cobalt species in biological matter and in biomacromolecular complexes (metalloenzymes), providing valuable structural information at the atomic level.

  15. Scandium doped Strontium Titanate Ceramics: Structure, Microstructure, and Dielectric Properties

    Directory of Open Access Journals (Sweden)

    Tkach, Alexander

    2008-08-01

    Full Text Available Sc-doped strontium titanate (ST ceramics were synthesised by solid state reaction, according to the composition Sr1-1.5xScxTiO3 with x = 0-0.01. Structural properties and microstructure development was examined by XRD and SEM. The dielectric properties were evaluated as a function of the temperature and frequency in the radio frequency range. Lattice parameter, density and grain size, were found to decrease slightly with increasing Sc content. The dielectric permittivity and losses decrease also. Sc-doping has only a weak effect on the quantum paraelectric behaviour of ST and no dielectric anomaly was observed, what is probably related to the limited solubility of Sc on the Sr site of the perovskite lattice of ST.

    Se sintetizaron materiales cerámicos de titanato de estroncio dopado con escandio mediante reacción en estado sólido De acuerdo a la composición Sr1-1.5xScxTiO3 con x= 0-0.1. Las propiedades estructurales y el desarrollo microestructural se estudiaron mediante XRD y SEM. La propiedades dieléctricas se estudiaron como función de la temperatura y de la frecuencia en el rango de la frecuencias de radio. Se observó que los parámetros de red, la densidad y el tamaño del grano disminuyen ligeramente con el contenido en Sc. La permitividad dieléctrica y las perdidas también disminuyen. El dopado con Sc tiene un efecto muy ligero sobre el comportamiento paraeléctrico cuántico del titanato de estroncio y no se observó anomalías dioeléctricas , lo que está probablemente relacionado con la baja solubilidad del Sc en posiciones del Sr en la estructura tipo perovskita del titanato de estroncio.

  16. Phenoxyl radical complexes of gallium, scandium, iron and manganese.

    Science.gov (United States)

    Adam, B; Bill, E; Bothe, E; Goerdt, B; Haselhorst, G; Hildenbrand, K; Sokolowski, A; Steenken, S; Weyhermüller, T; Wieghardt, K

    1997-02-01

    The hexadentate macrocyclic ligands 1,4,7-tris(3,5-dimethyl-2-hydroxybenzyl)-1,4,7-triazacyclononane (L CH 3H3 ), 1,4,7-tris(3,5-di-tert-butyl-2-hydroxybenzyl)-1,4,7-triazacyclononane (L(Bu) H3 ) and 1,4,7-tris(3-tert-butyl-5-methoxy-2-hydroxybenzyl)-1,4,7-triazacyclononane (L OCH 3-H3 ) form very stable octahedral neutral complexes LM(III) with trivalent (or tetravalent) metal ions (Ga(III) , Sc(III) , Fe(III) , Mn(III) , Mn(IV) ). The following complexes have been synthesized: [L(Bu) M], where M = Ga (1), Sc (2), Fe (3); [L(Bu) Mn(IV) ]PF6 (4'); [L OCH 3M], where M = Ga (1 a), Sc (2 a), Fe (3 a); [L OCH 3Mn(IV) ]PF6 (4 a'); [L CH 3M], where M = Sc (2 b), Fe (3 b), Mn(III) (4 b); [L CH 3Mn(IV) ]2 (ClO4 )3 (H3 O)(H2 O)3 (4 b'). An electrochemical study has shown that complexes 1, 2, 3, 1 a, 2 a and 3 a each display three reversible, ligand-centred, one-electron oxidation steps. The salts [L OCH 3Fe(III) ]ClO4 and [L OCH 3Ga(III) ]ClO4 , have been isolated as stable crystalline materials. Electronic and EPR spectra prove that these oxidations produce species containing one, two or three coordinated phenoxyl radicals. The Mössbauer spectra of 3 a and [3 a](+) show conclusively that both compounds contain high-spin iron(III) central ions. Temperature-dependent magnetic susceptibility measurements reveal that 3 a has an S = 5/2 and [3a](+) an S = 2 ground state. The latter is attained through intramolecular antiferromagnetic exchange coupling between a high-spin iron(III) (S1 = 5/2) and a phenoxyl radical (S2 = 1/2) (H = - 2JS1 S2 ; J = - 80 cm(-1) ). The manganese complexes undergo metal- and ligand-centred redox processes, which were elucidated by spectroelectrochemistry; a phenoxyl radical Mn(IV) complex [Mn(IV) L OCH 3](2+) is accessible. Copyright © 1997 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Atomic layer deposition of scandium-based oxides

    Energy Technology Data Exchange (ETDEWEB)

    Nyns, Laura; Lisoni, Judit G.; Bosch, Geert van den; Elshocht, Sven van; Houdt, Jan van [IMEC, Leuven (Belgium)

    2014-02-15

    Gd{sub x}Sc{sub 2-x}O{sub 3} and Al{sub x}Sc{sub 2-x}O{sub 3} have been investigated as potential high-k intergate dielectric (IGD) in planar NAND flash technology, such as hybrid floating gate (HFG). We have examined the atomic layer deposition (ALD) of Sc{sub 2}O{sub 3}, Gd{sub x}Sc{sub 2-x}O{sub 3}, and Al{sub x}Sc{sub 2-x}O{sub 3} on Si using Sc(MeCp){sub 3}, Gd({sup i}PrCp){sub 3}, TMA, and H{sub 2}O as precursors. The composition of Gd{sub x}Sc{sub 2-x}O{sub 3} and Al{sub x}Sc{sub 2-x}O{sub 3} ranged from 4% to 76% Gd and from 7% to 66% Al, respectively. All compositions show linear growth behavior. While pure Sc{sub 2}O{sub 3} is crystalline as-deposited, the layer becomes amorphous once ∝20% of Al is added. The (222) reflection of the cubic phase is also seen for Gd{sub x}Sc{sub 2-x}O{sub 3} with less than 9% Gd. The bandgap of as-deposited Gd{sub x}Sc{sub 2-x}O{sub 3} decreases with increasing Gd content while the opposite trend is observed for Al{sub x}Sc{sub 2-x}O{sub 3}. A k-value of ∝21 can be obtained for Gd{sub x}Sc{sub 2-x}O{sub 3} with approximately 26-52% Gd, irrespective of the Gd content. For Al{sub x}Sc{sub 2-x}O{sub 3} on the other hand, a maximum k-value of ∝19 is achieved with ∝48% Al. Although the k-value of Al{sub x}Sc{sub 2-x}O{sub 3} is lower than that of Gd{sub x}Sc{sub 2-x}O{sub 3}, its large breakdown field makes this material more suitable for HFG flash applications. (copyright 2014 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Spark plasma sintering of aluminum powders prealloyed with scandium additions

    Energy Technology Data Exchange (ETDEWEB)

    Cooke, R.W.; Kraus, N.P.; Bishop, D.P., E-mail: Paul.Bishop@dal.ca

    2016-03-07

    The objective of this research was to commence work on the spark plasma sintering (SPS) of Al–Sc alloys in an effort to develop fundamental data in this area. In this precursory study, a series of binary systems containing 0.1 to 0.4 wt% Sc were processed in laboratory and industrial-scale equipment. Data revealed that all powders were responsive to SPS in both scenarios and that sintering temperature was a variable of critical importance. Hardness of as-sintered products scaled directly with Sc concentration but varied inversely with SPS temperature owing to in-situ aging of the raw powders. Hardness losses could be recovered through a post-SPS heat treatment into the T6 condition. Industrially processed slugs of Al-0.4Sc-T6 exhibited full densification and offered the highest hardness (786+/−8 MPa). This was accompanied by a nominal tensile yield strength of 197 MPa, UTS of 226 MPa and tensile ductility of 11%.

  19. Tin etching from metallic and oxidized scandium thin films

    NARCIS (Netherlands)

    Pachecka, Malgorzata; Lee, Christopher James; Sturm, J.M.; Bijkerk, Frederik

    The role of oxide on Sn adhesion to Sc surfaces was studied with in-situ ellipsometry, X-ray photoelectron spectroscopy and secondary electron microscopy. Sn etching with hydrogen radicals was performed on metallic Sc, metallic Sc with a native oxide, and a fully oxidized Sc layer. The results show

  20. The structural and magnetic properties of holmium/scandium superlattices

    DEFF Research Database (Denmark)

    Bryn-Jacobsen, C.; Cowley, R.A.; McMorrow, D.F.

    1997-01-01

    The properties of Ho/Sc superlattices grown by molecular beam epitaxy (MBE) have been investigated using X-ray and neutron diffraction techniques. Structural studies reveal the novel existence of more than one a lattice parameter. Examining the magnetic properties, it is found that the Ho 4f...

  1. Hebrews 5:7 as the cry of the Davidic sufferer

    Directory of Open Access Journals (Sweden)

    Timothy Bertolet

    2017-10-01

    Full Text Available This article proposes a better source for the Son’s cry in Hebrews 5:7. It begins by surveying sources previous scholars have identified, including Jesus’ cry in Gethsemane and Golgotha, several Psalms, and the Maccabean martyr literature. It is then argued that these background sources for the language are insufficient. Instead the author of Hebrews has an entire motif from the Psalter as his informing source: the Davidic figure that cries out in trust to be delivered from a death-like experience. Firstly, the motif of the Davidic righteous suffering in the LXX Psalms is demonstrated. Secondly, Hebrews’ use of the Messianic royal figure is demonstrated and thirdly, Hebrews 5:7 as a portrait of the Christ who cries out for deliverance is demonstrated. Thus, Hebrews 5:7 sees the Son as the Davidic king who is the true representative human exercising trust in YHWH, bringing to fulfilment the theme from various Psalms.

  2. Virulence assessment of a Neospora caninum isolate for inbred C57BL/6 mouse

    Directory of Open Access Journals (Sweden)

    Lotfi, M.

    2012-06-01

    Full Text Available Neospora caninum (N. caninum is an apicomplexan parasite and causes abortion and congenital neosporosis in cattle worldwide. In this study, we evaluate the virulence of a N. caninum isolate on mouse strain C57BL/6. Six groups of five mice C57BL/6 were intraperitoneally inoculated with 1 × l07, 1.5 × l07, 2 × l07, 3 × l07 and 4 × l07 tachyzoites and a control inoculum of DMEM, respectively. Clinical signs and mortality rate were recorded and confirmed by histopathological findings and molecular method. The results of this study indicated that LD50 was 2.5 × l07 tachyzoites of N. caninum per C57BL/6 mouse. This can be used as a lethal challenge model in vaccine development studies.

  3. Postnatal Hematopoiesis and Gut Microbiota in NOD Mice Deviate from C57BL/6 Mice

    Directory of Open Access Journals (Sweden)

    Dina Silke Malling Damlund

    2016-01-01

    Full Text Available Neonatal studies in different mouse strains reveal that early life colonization affects the development of adaptive immunity in mice. The nonobese diabetic (NOD mouse spontaneously develops autoimmune diabetes, but neonatal studies of NOD mice are lacking. We hypothesized that NOD mice deviate from another much used mouse strain, C57BL/6, with respect to postnatal microbiota and/or hematopoiesis and compared this in newborn mice of dams housed under the same conditions. A distinct bacteria profile rich in staphylococci was found at postnatal days (PND 1–4 in NOD mice. Furthermore, a distinct splenic cell profile high in a granulocytic phenotype was evident in the neonatal NOD mice whereas neonatal C57BL/6 mice showed a profile rich in monocytes. Neonatal expression of Reg3g and Muc2 in the gut was deviating in NOD mice and coincided with fewer bacteria attaching to the Mucosal surface in NOD compared to C57BL/6 mice.

  4. A Critical Role for Cysteine 57 in the Biological Functions of Selenium Binding Protein-1

    Directory of Open Access Journals (Sweden)

    Qi Ying

    2015-11-01

    Full Text Available The concentration of selenium-binding protein1 (SBP1 is often lower in tumors than in the corresponding tissue and lower levels have been associated with poor clinical outcomes. SBP1 binds tightly selenium although what role selenium plays in its biological functions remains unknown. Previous studies indicated that cysteine 57 is the most likely candidate amino acid for selenium binding. In order to investigate the role of cysteine 57 in SBP1, this amino acid was altered to a glycine and the mutated protein was expressed in human cancer cells. The SBP1 half-life, as well as the cellular response to selenite cytotoxicity, was altered by this change. The ectopic expression of SBP1GLY also caused mitochondrial damage in HCT116 cells. Taken together, these results indicated that cysteine 57 is a critical determinant of SBP1 function and may play a significant role in mitochondrial function.

  5. Hebrews 5:7 as the cry of the Davidic sufferer

    Directory of Open Access Journals (Sweden)

    Timothy Bertolet

    2017-02-01

    Full Text Available This article proposes a better source for the Son’s cry in Hebrews 5:7. It begins by surveying sources previous scholars have identified, including Jesus’ cry in Gethsemane and Golgotha, several Psalms, and the Maccabean martyr literature. It is then argued that these background sources for the language are insufficient. Instead the author of Hebrews has an entire motif from the Psalter as his informing source: the Davidic figure that cries out in trust to be delivered from a death-like experience. Firstly, the motif of the Davidic righteous suffering in the LXX Psalms is demonstrated. Secondly, Hebrews’ use of the Messianic royal figure is demonstrated and thirdly, Hebrews 5:7 as a portrait of the Christ who cries out for deliverance is demonstrated. Thus, Hebrews 5:7 sees the Son as the Davidic king who is the true representative human exercising trust in YHWH, bringing to fulfilment the theme from various Psalms.

  6. Core drilling of deep drillhole OL-KR57 at Olkiluoto in Eurajoki 2011-2012

    Energy Technology Data Exchange (ETDEWEB)

    Toropainen, V. [Suomen Malmi Oy, Espoo (Finland)

    2012-07-15

    As a part of the confirming site investigations at Olkiluoto, Suomen Malmi Oy (Smoy) core drilled 401.71 m and 45.01 m deep drillholes, OL-KR57 and OL-KR57B, at Olkiluoto in September 2011 - January 2012. The diameter of the drillholes is 75.7 mm. A set of monitoring measurements and samplings from the drilling and returning water was carried out during the drilling. Both the volume and the electric conductivity of the returning and drilling water were recorded. The drill rig was computer controlled and the computer recorded drilling parameters during drilling. The objective of the measurements was to obtain more information about bedrock and groundwater properties. Sodium fluorescein was used as a label agent in the drilling water. The total volumes of the used drilling, flushing and washing water were 350 m3 and 30 m3 in the drillholes OL-KR57 and OL-KR57B, respectively. The measured volumes of the returning water in the drillholes were 328 m{sup 3} and 16.8 m{sup 3}, respectively. The deviations of the drillholes were measured with the deviation measuring instruments EMS and Gyro. Uniaxial compressive strength, Young's Modulus and Poisson's ratio were measured from the core samples. The average uniaxial compressive strength was 123.9 MPa, the average Young's Modulus was 42.6 GPa and the average Poisson's ratio was 0.23. The main rock types are veined and diatexitic gneisses, mica gneiss and tonaliticgranodioritic- granitic gneiss. The average fracture frequency is 2.5 pcs/m in drillhole OL-KR57 and 3.3 pcs/m in the drillhole OL-KR57B. The average RQD values are 95.0 % and 93.0 %. Seven separate fractured zones were interpreted from OL-KR57 and three fractured zones from OL-KR57B. (orig.)

  7. Vacancy ordering in γ-Fe 2O 3 nanocrystals observed by 57Fe NMR

    Science.gov (United States)

    Bastow, T. J.; Trinchi, A.; Hill, M. R.; Harris, R.; Muster, T. H.

    2009-09-01

    The identification by 57Fe internal field nuclear magnetic resonance (NMR) of hyperfine fields at four Fe sites in the (average) tetragonal unit cell of vacancy-ordered γ-Fe 2O 3 (maghemite) is reported. The effects of vacancy redistribution due to annealing the partially vacancy-ordered form has been observed in the 57Fe lineshape. In addition, the reduction of the particle size of the vacancy-ordered form has been observed to gradually eliminate the vacancy ordering and then to cause a transition from ferrimagnetism to superparamagnetism.

  8. Environmental Enrichment Reduces the Likelihood of Alopecia in Adult C57BL/6J Mice

    Science.gov (United States)

    Bechard, Allison; Meagher, Rebecca; Mason, Georgia

    2011-01-01

    Barbering (incessant grooming) is an abnormal behavior causing alopecia and commonly affects various strains of laboratory mice, including C57BL/6J. Barbering-induced alopecia is a potential symptom of brain impairment and can indicate a stressful environment. We compared alopecia prevalence and severity in mice housed in enriched or standard cages. Providing an enriched environment delayed the onset and reduced the prevalence and overall severity of alopecia in C57BL/6J mice. Husbandry methods that reduce adult alopecia are likely to promote the wellbeing of the animals. We suggest that environmental enrichment is a simple and economic way to reduce alopecia in mouse colonies. PMID:21439209

  9. Withdrawal from Chronic Nicotine Administration Impairs Contextual Fear Conditioning in C57BL/6 Mice

    OpenAIRE

    Davis, Jennifer A.; James, John R.; Siegel, Steven J.; Gould, Thomas J.

    2005-01-01

    The effects of acute nicotine administration (0.09 mg/kg nicotine), chronic nicotine administration (6.3 mg/kg/d nicotine for 14 d), and withdrawal from chronic nicotine administration on fear conditioning in C57BL/6 mice were examined. Mice were trained using two coterminating conditioned stimulus (30 s; 85 dB white noise)– unconditioned stimulus (2 s; 0.57 mA foot shock) pairings and tested 24 h later for contextual and cued fear conditioning. Acute nicotine administration enhanced contextu...

  10. SYNTHESIS OF 5,7-DIHYDROXY-3’,4’-DIMETHOXYISOFLAVON FROM EUGENOL

    Directory of Open Access Journals (Sweden)

    Andi Hairil Alimuddin

    2011-12-01

    Full Text Available Synthesis of 5,7-dihydroxy-3',4'-dimethoxyisoflavone from eugenol as isolated product of clove leaves oil had been done. Eugenol was firstly converted into 3,4-dimethoxybenzyl cyanide via several stages of reaction. Hoeben-Hoesch reaction of 3,4-dimethoxybenzyl cyanide with phloroglucin produced 3,4-dimethoxybenzyl-2',4',6'-trihydroxyphenyl ketone (deoxybenzoin intermediate in 58% yield. Eventually, cyclization of the intermediate with reagents of BF3.OEt2/DMF/POCl3 yielded 5,7-dihydroxy-3',4'-isoflavone in 88% yield.

  11. ASTM E57 3D imaging systems committee: an update on the standards development effort

    Science.gov (United States)

    Lytle, Alan M.; Cheok, Gerry; Saidi, Kamel

    2007-04-01

    In June 2006, a new ASTM committee (E57) was established to develop standards for 3D imaging systems. This committee is the result of a 4-year effort at the National Institute of Standards and Technology to develop performance evaluation and characterization methods for such systems. The initial focus for the committee will be on standards for 3D imaging systems typically used for applications including, but not limited to, construction and maintenance, surveying, mapping and terrain characterization, manufacturing (e.g., aerospace, shipbuilding), transportation, mining, mobility, historic preservation, and forensics. This paper reports the status of current efforts of the ASTM E57 3D Imaging Systems committee.

  12. {sup 57}Fe emission Mössbauer spectroscopy following dilute implantation of {sup 57}Mn into In {sub 2}O{sub 3}

    Energy Technology Data Exchange (ETDEWEB)

    Mokhles Gerami, A.; Johnston, K.; Gunnlaugsson, H. P., E-mail: Haraldur.p.gunnlaugsson@cern.ch [PH Div, CERN (Switzerland); Nomura, K. [Tokyo University of Science, Photocatalysis International Research Center (Japan); Mantovan, R. [IMM-CNR, Laboratorio MDM (Italy); Masenda, H. [University of the Witwatersrand, School of Physics (South Africa); Matveyev, Y. A. [Moscow Institute of Physics and Technology (Russian Federation); Mølholt, T. E. [PH Div, CERN (Switzerland); Ncube, M. [University of the Witwatersrand, School of Physics (South Africa); Shayestehaminzadeh, S. [University of Iceland, Science Institute (Iceland); Unzueta, I. [Euskal Herriko Unibertsitatea (UPV/EHU), BCMaterials & Elektrizitate eta Elektronika Saila (Spain); Gislason, H. P. [University of Iceland, Science Institute (Iceland); Krastev, P. B. [Bulgarian Academy of Sciences, Institute for Nuclear Research and Nuclear Energy (Bulgaria); Langouche, G. [Instituut voor Kern-en Stralings Fysika, KU Leuven (Belgium); Naidoo, D. [University of the Witwatersrand, School of Physics (South Africa); Ólafsson, S. [University of Iceland, Science Institute (Iceland); Collaboration: the ISOLDE collaboration

    2016-12-15

    Emission Mössbauer spectroscopy has been utilised to characterize dilute {sup 57}Fe impurities in In {sub 2}O{sub 3} following implantation of {sup 57}Mn (T{sub 1/2} = 1.5 min.) at the ISOLDE facility at CERN. From stoichiometry considerations, one would expect Fe to adopt the valence state 3 + , substituting In {sup 3+}, however the spectra are dominated by spectral lines due to paramagnetic Fe{sup 2+}. Using first principle calculations in the framework of density functional theory (DFT), the density of states of dilute Fe and the hyperfine parameters have been determined. The hybridization between the 3d-band of Fe and the 2p band of oxygen induces a spin-polarized hole on the O site close to the Fe site, which is found to be the cause of the Fe{sup 2+} state in In {sub 2}O{sub 3}. Comparison of experimental data to calculated hyperfine parameters suggests that Fe predominantly enters the 8b site rather than the 24d site of the cation site in the Bixbyite structure of In {sub 2}O{sub 3}. A gradual transition from an amorphous to a crystalline state is observed with increasing implantation/annealing temperature.

  13. Absence/presence and the ontological politics of heritage: the case of Barrack 57

    NARCIS (Netherlands)

    Felder, M.; Duineveld, Martijn; Assche, van Kristof

    2015-01-01

    19 July 2009. A barn burns down in a small Dutch town. Afterwards, this invisible and insignificant ‘barn’ became widely known as ‘Barrack 57’. The destruction triggered attention and led to the barn’s association with a Nazi Second World War transit camp and with Anne Frank. Its material

  14. Thymic lymphoepithelial interactions in the pathogenesis of radiation-induced lymphomas in C57BL mice

    Energy Technology Data Exchange (ETDEWEB)

    Houben-Defresne, M.P.; Lenaerts, P.; Greimers, R.; Boniver, J. (Universite de Liege au Sart Tilman (Belgium))

    1984-01-01

    In C57BL/Ka mice, leukemogenic fractionated wholebody X-irradiation induces alterations of the lymphoepithelial interactions normally found in the Thymic Nurse Cells (TNCs) and leads to the disappearance of these complexes. This phenomenon is due to disturbances of thymic lymphopoiesis caused by modifications of bone marrow prothymocytes and of the epithelial component of TNCs.

  15. The inhibitory efficacy of methylseleninic acid against colon cancer xenografts in C57BL/6 mice

    Science.gov (United States)

    Data indicate that methylselenol is a critical selenium (Se) metabolite for anticancer activity in vivo. We tested the hypoththesis that oral dosing methylseleninic acid (MSeA), a methylselenol precursor, inhibits the growth of colon cancer xenografts in C57BL/6 mice fed a Se adequate diet. In this...

  16. 57th Yearbook of the National Reading Conference (Austin, Texas, November 28-December 1, 2007)

    Science.gov (United States)

    Kim, Youb, Ed.; Risko, Victoria J., Ed.; Compton, Donald L., Ed.; Dickinson, David K., Ed.; Hundley, Melanie K., Ed.; Jimenez, Robert T., Ed.; Leander, Kevin M., Ed.; Rowe, Deborah Wells, Ed.

    2008-01-01

    This publication offers the 57th Yearbook of the National Reading Conference (NRC). This Yearbook begins with a preface and presents profiles of two awardees, John E. McEneaney and Scott G. Paris. Included in this Yearbook are the following papers: (1) The Education of African-American Students: Voicing the Debates, Controversies, and Solutions…

  17. 30 CFR 57.12069 - Lightning protection for telephone wires and ungrounded conductors.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Lightning protection for telephone wires and... AND NONMETAL MINES Electricity Surface Only § 57.12069 Lightning protection for telephone wires and... resistance grounding medium on the surface and shall be separated from neutral grounds by a distance of not...

  18. 49 CFR 325.57 - Location and operation of sound level measurement systems; stationary test.

    Science.gov (United States)

    2010-10-01

    ... vehicle being measured. (c) The microphone of the sound level measurement system shall be oriented toward... 49 Transportation 5 2010-10-01 2010-10-01 false Location and operation of sound level measurement...; Stationary Test § 325.57 Location and operation of sound level measurement systems; stationary test. (a) The...

  19. Analytical Method Details (MS): SE57_MS02 [Metabolonote[Archive

    Lifescience Database Archive (English)

    Full Text Available SE57_MS02 UPLC-TQMS analysis UPLC (Waters) The UPLC (Waters) conditions were manual... 100%; 2.1 min, 100%; 2.11 min, 0%); 3 min cycles with a temperature of 38°C.The TQMS detection conditions w

  20. 30 CFR 57.4130 - Surface electric substations and liquid storage facilities.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Surface electric substations and liquid storage... accumulate within 25 feet of the following: (1) Electric substations. (2) Unburied, flammable or combustible... NONMETAL MINES Fire Prevention and Control Prohibitions/precautions/housekeeping § 57.4130 Surface electric...

  1. 30 CFR 57.16002 - Bins, hoppers, silos, tanks, and surge piles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bins, hoppers, silos, tanks, and surge piles... NONMETAL MINES Materials Storage and Handling § 57.16002 Bins, hoppers, silos, tanks, and surge piles. (a) Bins, hoppers, silos, tanks, and surge piles, where loose unconsolidated materials are stored, handled...

  2. 77 FR 13951 - Federal Acquisition Regulation; Federal Acquisition Circular 2005-57; Introduction

    Science.gov (United States)

    2012-03-07

    ..., is available via the Internet at http://www.regulations.gov . DATES: For effective date and comment... Administration 48 CFR Chapter 1 Federal Acquisition Regulation; Federal Acquisition Circular 2005-57...;Federal Register / Vol. 77 , No. 45 / Wednesday, March 7, 2012 / Rules and Regulations#0;#0; ] DEPARTMENT...

  3. Bull.Chem.Soc.Ethiop., 1(2), 57—63

    African Journals Online (AJOL)

    Ethiop., 1(2), 57—63 (1987). COORDINATION COMPOUNDS OF METAL CHELATES OF SULPHUR. CONTAINING LIGANDS WITH LEWIS BASES. Reaction of bis(S—-methyl~N—arylidenehydrazine carbodithioate)- nickelfil) Chelates with Pyridine and 1,10—Phenanthroline. Salah S. Massoud. Chemistry Department ...

  4. The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    DEFF Research Database (Denmark)

    Rune, Ida; Nielsen, Dennis Sandris; Hansen, Axel Jacob Kornerup

    Background Recent studies have shown that long term broad spectrum antibiotic treatment improves glucose tolerance in mice. We hypothesize that it is primarily the early life altering of the gut microbiota, which will have an impact on glucose intolerance. Study setup 40 C57BL/6NTac mice were...

  5. 30 CFR 57.9303 - Construction of ramps and dumping facilities.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Construction of ramps and dumping facilities... MINES Loading, Hauling, and Dumping Safety Devices, Provisions, and Procedures for Roadways, Railroads, and Loading and Dumping Sites § 57.9303 Construction of ramps and dumping facilities. Ramps and...

  6. Postnatal hematopoiesis and gut microbiota in NOD mice deviate from C57BL/6 mice

    DEFF Research Database (Denmark)

    Damlund, Dina Silke Malling; Metzdorff, Stine Broeng; Hasselby, Jane Preuss

    2016-01-01

    from another much used mouse strain, C57BL/6, with respect to postnatal microbiota and/or hematopoiesis and compared this in newborn mice of dams housed under the same conditions. A distinct bacteria profile rich in staphylococci was found at postnatal days (PND) 1-4 in NOD mice. Furthermore...

  7. 19 CFR 10.57 - Certified seed potatoes, and seed corn or maize.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Certified seed potatoes, and seed corn or maize... Provisions Potatoes, Corn, Or Maize § 10.57 Certified seed potatoes, and seed corn or maize. Claim for classification as seed potatoes under subheading 0701.10.00, as seed corn (maize) under subheading 1005.10...

  8. 42 CFR 57.310 - Repayment and collection of nursing student loans.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Repayment and collection of nursing student loans... LOANS Nursing Student Loans § 57.310 Repayment and collection of nursing student loans. (a) Each nursing.... 1 1 Individuals who received nursing student loans prior to July 1, 1969, remain subject to the...

  9. 42 CFR 57.306 - Eligibility and selection of nursing student loan applicants.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Eligibility and selection of nursing student loan... STUDENT LOANS Nursing Student Loans § 57.306 Eligibility and selection of nursing student loan applicants. (a) Determination of eligibility. (1) Applicants are eligible for consideration for a nursing student...

  10. Achary Ganesha see Sachin HP 57 Effect of a new condensation ...

    Indian Academy of Sciences (India)

    WINTEC

    Achary Ganesha see Sachin H P. 57. Effect of a new condensation product on electrodeposition of zinc from a non-cyanide bath. 219. Agnihotry S A see Ahmad Shahzada. 31. Ahmad A A. Adhesive B-doped DLC films on biomedical alloys used for bone fixation. 301 see Alsaad A M. 407. Ahmad Shahzada. Synthesis and ...

  11. SYNTHESIS OF POLY-5,7-DIALLYL-25,26,27,28-TETRAHYDROXYCALIX[4]ARENE

    Directory of Open Access Journals (Sweden)

    Desi Suci Handayani

    2010-06-01

    Full Text Available The synthesis of poly-5,7-diallyl-25,26,27,28-tetrahydroxycalix[4]arene were performed in experimental series as follows: (1 Cyclotetramerization of p-t-butylphenol with NaOH and paraformaldehyde to p-butylcalix[4]arene, (2 Debutylation of p-butylcalix[4]arene using AlCl3 and phenol to tetrahydroxycalix[4]arene, (3 Allylation reaction using allylbromide to diallyloxy-dihydroxycalix[4]arene, (4 Claisen rearrangement reaction, (5 Cationic polymerization to diallylcalix[4]arenes. All of the synthesized products were analyzed by means of IR spectrometer and 1H-NMR spectrometer. The result of 25,27-diallyloxy-26,28-dihydroxycalix[4]arene synthesis was white crystals having m.p. 205-207 °C in 80.95% yield. The synthesis of 5,7-diallyl-25,26,27,28-tetrahydroxy-calix[4]arene gave light yellow crystals having m.p. 214-216 °C in 78.67% yield. The polymerization gave poly(5,7-diallyl-25,26,27,28-tetra-hydroxycalix[4]arene having m.p. 338-340 °C, in 60% yield. Its estimated has a relative molecular weight of 18,738 g/mol with the number of unit repetition about 37 monomer units.   Keywords: Diallylation, polymerization, Poly-5,7-diallyl-25,26,27,28-tetrahydroxycalix[4]arene

  12. Confirmation of a high magnetic field in GRO J1008-57

    DEFF Research Database (Denmark)

    Bellm, Eric C.; Fuerst, Felix; Pottschmidt, Katja

    2014-01-01

    GRO J1008-57 is a high-mass X-ray binary for which several claims of a cyclotron resonance scattering feature near 80 keV have been reported. We use NuSTAR, Suzaku, and Swift data from its giant outburst of 2012 November to confirm the existence of the 80 keV feature and perform the most sensitive...

  13. Deep far infrared ISOPHOT survey in "Selected Area 57" - I. Observations and source counts

    DEFF Research Database (Denmark)

    Linden-Vornle, M.J.D.; Nørgaard-Nielsen, Hans Ulrik; Jørgensen, H.E.

    2000-01-01

    We present here the results of a deep survey in a 0.4 deg(2) blank field in Selected Area 57 conducted with the ISOPHOT instrument aboard ESAs Infrared Space Observatory (ISO1) at both 60 mu m and 90 mu m. The resulting sky maps have a spatial resolution of 15 x 23 arcsrc(2) per pixel which is much...

  14. Transient neonatal diabetes, ZFP57, and hypomethylation of multiple imprinted loci

    DEFF Research Database (Denmark)

    Boonen, Susanne E; Mackay, Deborah J G; Hahnemann, Johanne M D

    2013-01-01

    Transient neonatal diabetes mellitus 1 (TNDM1) is the most common cause of diabetes presenting at birth. Approximately 5% of the cases are due to recessive ZFP57 mutations, causing hypomethylation at the TNDM locus and other imprinted loci (HIL). This has consequences for patient care because...

  15. Täna õhtul Berliinis, 57. korda / Lauri Kärk

    Index Scriptorium Estoniae

    Kärk, Lauri, 1954-

    2007-01-01

    57. Berlinale avamise eel. Programmidest, ava- ja lõpufilmidest. Lastefilmide võistlusprogrammis on ka "Leiutajateküla Lotte". Rain Tolk esindab Eestit Euroopa noorte näitlejate tutvustuspromotsioonis Shooting Star. Riina Sildos on lühifilmide žüriis

  16. Spectral Variability of Quasar SDSS J030639.57+000343.1 ...

    Indian Academy of Sciences (India)

    Spectral Variability of Quasar SDSS J030639.57+000343.1. Hengxiao Guo1,2,∗ & Minfeng Gu1. 1Key Laboratory for Research in Galaxies and Cosmology, Shanghai Astronomical. Observatory, Chinese Academy of Sciences, 80 Nandan Road, Shanghai 200030, China. 2University of Chinese Academy of Sciences, 19A ...

  17. 7 CFR 1219.57 - Patents, copyrights, trademarks, publications, and product formulations.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Patents, copyrights, trademarks, publications, and..., and Information Order Budgets, Expenses, and Assessments § 1219.57 Patents, copyrights, trademarks, publications, and product formulations. (a) Any patents, copyrights, trademarks, inventions, information...

  18. Revisiting the Canterbury earthquake sequence after the 14 February 2016 Mw 5.7 event

    NARCIS (Netherlands)

    Herman, Matthew W.; Furlong, Kevin P.

    2016-01-01

    On 14 February 2016, an Mw 5.7 (GNS Science moment magnitude) earthquake ruptured offshore east of Christchurch, New Zealand. This earthquake occurred in an area that had previously experienced significant seismicity from 2010 to 2012 during the Canterbury earthquake sequence, starting with the 2010

  19. Food Safety Knowledge and Behaviours of Children (5-7 Years)

    Science.gov (United States)

    Eves, Anita; Bielby, Gill; Egan, Bernadette; Lumbers, Margaret; Raats, Monique; Adams, Martin

    2010-01-01

    Objective: The objective of this study was to determine knowledge of food hygiene amongst young children (5-7 years), and facilitators and barriers to application of knowledge. Few studies exist that explore the knowledge and attitudes of young children towards food hygiene. This is an important age group, as it is a time when attitudes and…

  20. FXR agonist GW4064 increases plasma glucocorticoid levels in C57BL/6 mice

    NARCIS (Netherlands)

    Hoekstra, Menno; van der Sluis, Ronald J.; Li, Zhaosha; Oosterveer, Maaike H.; Groen, Albert K.; Van Berkel, Theo J. C.

    2012-01-01

    Since high expression of farnesoid X receptor (FXR) has been detected in glucocorticoid-producing adrenocortical cells, we evaluated the potential role of FXR in adrenal glucocorticoid production. FXR agonist GW4064 increased fasting plasma corticosterone levels (+45%; P <0.01) in C57BL/6 mice,

  1. 30 CFR 57.12005 - Protection of power conductors from mobile equipment.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protection of power conductors from mobile... NONMETAL MINES Electricity Surface and Underground § 57.12005 Protection of power conductors from mobile equipment. Mobile equipment shall not run over power conductors, nor shall loads be dragged over power...

  2. 30 CFR 57.4262 - Underground transformer stations, combustible liquid storage and dispensing areas, pump rooms...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Underground transformer stations, combustible... and Control Firefighting Equipment § 57.4262 Underground transformer stations, combustible liquid storage and dispensing areas, pump rooms, compressor rooms, and hoist rooms. Transformer stations, storage...

  3. Bulletin of Animal Health and Production in Africa - Vol 57, No 1 (2009)

    African Journals Online (AJOL)

    Determination of serological prevalence of animal trypanosomosis in the Kachia grazing reserve by inhibition ELISA · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. FNC Enwezor, G Enwezor, KAN Esievo, JU Umoh, LT Zaria, JI Anere. http://dx.doi.org/10.4314/bahpa.v57i1.

  4. Bulletin of Animal Health and Production in Africa - Vol 57, No 4 (2009)

    African Journals Online (AJOL)

    Epidemiological and biochemical studies on bovine anaplamosis in dakahlia and demiatta governorates in Egypt · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. E.E Younis, N.A.M Hegazy, W El-Deeb, R.M El-khatib. http://dx.doi.org/10.4314/bahpa.v57i4.51668 ...

  5. 7 CFR 3565.57 - Modification, extension, reinstatement of loan guarantee.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 15 2010-01-01 2010-01-01 false Modification, extension, reinstatement of loan...) RURAL HOUSING SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEED RURAL RENTAL HOUSING PROGRAM Guarantee Requirements § 3565.57 Modification, extension, reinstatement of loan guarantee. To protect its interest or...

  6. 42 CFR 57.2205 - Priority for selection of scholarship recipients.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Priority for selection of scholarship recipients... GRANTS GRANTS FOR CONSTRUCTION OF TEACHING FACILITIES, EDUCATIONAL IMPROVEMENTS, SCHOLARSHIPS AND STUDENT LOANS Physician Shortage Area Scholarship Grants § 57.2205 Priority for selection of scholarship...

  7. 27 CFR 27.57 - Containers in excess of 1 gallon.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Containers in excess of 1... BUREAU, DEPARTMENT OF THE TREASURY LIQUORS IMPORTATION OF DISTILLED SPIRITS, WINES, AND BEER General Requirements Packaging and Marking of Distilled Spirits § 27.57 Containers in excess of 1 gallon. Imported...

  8. Development of socketed foundations for S3X5.7 posts.

    Science.gov (United States)

    2015-04-01

    The objective of this study was to develop a socketed foundation for use with the S3x5.7 (S76x8.5) weak : post. The design focused on cylindrical, reinforced concrete foundations with a steel tube placed in the center for : use as the socket. The fou...

  9. 30 CFR 57.18028 - Mine emergency and self-rescuer training.

    Science.gov (United States)

    2010-07-01

    ... going underground. (c) All instructional material, handouts, visual aids, and other such teaching....18028 Section 57.18028 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL...

  10. 30 CFR 57.12081 - Bonding metal pipelines to ground return circuits.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bonding metal pipelines to ground return... LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS-UNDERGROUND METAL AND NONMETAL MINES Electricity Underground Only § 57.12081 Bonding metal pipelines to ground return circuits...

  11. Three-dimensional optokinetic eye movements in the C57BL/6J mouse

    NARCIS (Netherlands)

    B. van Alphen (Bart); B.H.J. Winkelman (Beerend); M.A. Frens (Maarten)

    2010-01-01

    textabstractPURPOSE. To study three-dimensional optokinetic eye movements of wild-type C57BL/6J mice, the most commonly used mouse in oculomotor physiology. Optokinetic eye movements are reflexive eye movements that use visual feedback to minimize image motion across the retina. These

  12. Heterologous expression of AtWRKY57 confers drought tolerance in Oryza sativa

    Directory of Open Access Journals (Sweden)

    Yanjuan eJiang

    2016-02-01

    Full Text Available Drought stress is a severe environmental factor that greatly restricts plant distribution and crop production. Recently, we have found that overexpressing AtWRKY57 enhanced drought tolerance in Arabidopsis thaliana. In this study, we further reported that the Arabidopsis WRKY57 transcription factor was able to confer drought tolerance to transgenic rice (Oryza sativa plants. The enhanced drought tolerance of transgenic rice was resulted from the lower water loss rates, cell death, malondialdehyde contents and relative electrolyte leakage while a higher proline content and reactive oxygen species-scavenging enzyme activities was observed during stress conditions. Moreover, further investigation revealed that the expression levels of several stress-responsive genes were up-regulated in drought-tolerant transgenic rice plants, compared with those in wild-type plants. In addition to the drought tolerance, the AtWRKY57 over-expressing plants also had enhanced salt and PEG stress tolerances. Taken together, our study indicates that over-expressing AtWRKY57 in rice improved not only drought tolerance but also salt and PEG tolerance, demonstrating its potential role in crop improvement.

  13. 7 CFR 1484.57 - Will FAS make advance payments to a Cooperator?

    Science.gov (United States)

    2010-01-01

    ... DEVELOP FOREIGN MARKETS FOR AGRICULTURAL COMMODITIES Contributions and Reimbursements § 1484.57 Will FAS make advance payments to a Cooperator? (a) Policy. In general, FAS operates the Cooperator program on a.... The first is a revolving fund operating advance provided by FAS only to Cooperators with foreign...

  14. Project 57 Air Monitoring Report: October 1, 2013, through December 31, 2014

    Energy Technology Data Exchange (ETDEWEB)

    Mizell, Steve A. [Desert Research Inst. (DRI), Las Vegas, NV (United States); Nikolich, George [Desert Research Inst. (DRI), Las Vegas, NV (United States); McCurdy, Greg [Desert Research Inst. (DRI), Reno, NV (United States); Shadel, Craig [Desert Research Inst. (DRI), Las Vegas, NV (United States); Miller, Julianne J. [Desert Research Inst. (DRI), Las Vegas, NV (United States)

    2016-02-01

    On April 24, 1957, the Atomic Energy Commission (AEC, now the Department of Energy [DOE]) conducted the Project 57 safety experiment in western Emigrant Valley north east of the Nevada National Security Site (NNSS, formerly the Nevada Test Site) on lands withdrawn by the Department of Defense (DoD) for the Nevada Test and Training Range (NTTR). The test was undertaken to develop (1) a means of estimating plutonium distribution resulting from a nonnuclear detonation; (2) biomedical evaluation techniques for use in plutonium-laden environments; (3) methods of surface decontamination; and (4) instruments and field procedures for prompt estimation of alpha contamination (Shreve, 1958). Although the test did not result in the fission of nuclear materials, it did disseminate plutonium across the land surface. Following the experiment, the AEC fenced the contaminated area and returned control of the surrounding land to the DoD. Various radiological surveys have been performed in the area and in 2007, the DOE expanded the demarked contamination area by posting signs 200 to 400 feet (60 to 120 meters) outside of the original fence. Plutonium in soil is thought to attach preferentially to smaller particles. Therefore, redistribution of soil particulates by wind (dust) is the mechanism most likely to transport plutonium beyond the boundary of the Project 57 contamination area. In 2011, DRI installed two instrumentation towers to measure radiological, meteorological, and dust conditions. The monitoring activity was implemented to determine if radionuclide contamination was detectable in samples of airborne dust and characterize meteorological and environmental parameters that influence dust transport. Collected data also permits comparison of radiological conditions at the Project 57 monitoring stations to conditions observed at Community Environmental Monitoring Program (CEMP) stations around the NTTR. Biweekly samples of airborne particulates are submitted for laboratory

  15. Junctional adhesion molecule (JAM-C deficient C57BL/6 mice develop a severe hydrocephalus.

    Directory of Open Access Journals (Sweden)

    Lena Wyss

    Full Text Available The junctional adhesion molecule (JAM-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS has been poorly characterized to date. Here we show that JAM-C(-/- mice backcrossed onto the C57BL/6 genetic background developed a severe hydrocephalus. An in depth immunohistochemical study revealed specific immunostaining for JAM-C in vascular endothelial cells in the CNS parenchyma, the meninges and in the choroid plexus of healthy C57BL/6 mice. Additional JAM-C immunostaining was detected on ependymal cells lining the ventricles and on choroid plexus epithelial cells. Despite the presence of hemorrhages in the brains of JAM-C(-/- mice, our study demonstrates that development of the hydrocephalus was not due to a vascular function of JAM-C as endothelial re-expression of JAM-C failed to rescue the hydrocephalus phenotype of JAM-C(-/- C57BL/6 mice. Evaluation of cerebrospinal fluid (CSF circulation within the ventricular system of JAM-C(-/- mice excluded occlusion of the cerebral aqueduct as the cause of hydrocephalus development but showed the acquisition of a block or reduction of CSF drainage from the lateral to the 3(rd ventricle in JAM-C(-/- C57BL/6 mice. Taken together, our study suggests that JAM-C(-/- C57BL/6 mice model the important role for JAM-C in brain development and CSF homeostasis as recently observed in humans with a loss-of-function mutation in JAM-C.

  16. Junctional adhesion molecule (JAM)-C deficient C57BL/6 mice develop a severe hydrocephalus.

    Science.gov (United States)

    Wyss, Lena; Schäfer, Julia; Liebner, Stefan; Mittelbronn, Michel; Deutsch, Urban; Enzmann, Gaby; Adams, Ralf H; Aurrand-Lions, Michel; Plate, Karl H; Imhof, Beat A; Engelhardt, Britta

    2012-01-01

    The junctional adhesion molecule (JAM)-C is a widely expressed adhesion molecule regulating cell adhesion, cell polarity and inflammation. JAM-C expression and function in the central nervous system (CNS) has been poorly characterized to date. Here we show that JAM-C(-/-) mice backcrossed onto the C57BL/6 genetic background developed a severe hydrocephalus. An in depth immunohistochemical study revealed specific immunostaining for JAM-C in vascular endothelial cells in the CNS parenchyma, the meninges and in the choroid plexus of healthy C57BL/6 mice. Additional JAM-C immunostaining was detected on ependymal cells lining the ventricles and on choroid plexus epithelial cells. Despite the presence of hemorrhages in the brains of JAM-C(-/-) mice, our study demonstrates that development of the hydrocephalus was not due to a vascular function of JAM-C as endothelial re-expression of JAM-C failed to rescue the hydrocephalus phenotype of JAM-C(-/-) C57BL/6 mice. Evaluation of cerebrospinal fluid (CSF) circulation within the ventricular system of JAM-C(-/-) mice excluded occlusion of the cerebral aqueduct as the cause of hydrocephalus development but showed the acquisition of a block or reduction of CSF drainage from the lateral to the 3(rd) ventricle in JAM-C(-/-) C57BL/6 mice. Taken together, our study suggests that JAM-C(-/-) C57BL/6 mice model the important role for JAM-C in brain development and CSF homeostasis as recently observed in humans with a loss-of-function mutation in JAM-C.

  17. Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice

    Science.gov (United States)

    Smith, Kiersten S.; Meloni, Edward G.; Myers, Karyn M.; Veer, Ashlee Van't; Carlezon, William A.; Rudolph, Uwe

    2011-01-01

    Rationale Anxiety disorders affect 18% of the United States adult population annually. Recent surges in the diagnosis of posttraumatic stress disorder (PTSD) from combat-exposed veterans have prompted an urgent need to understand the pathophysiology underlying this debilitating condition. Objectives Anxiety and fear responses are partly modulated by gamma aminobutyric acid type A (GABAA) receptor-mediated synaptic inhibition; benzodiazepines potentiate GABAergic inhibition and are effective anxiolytics. Many genetically modified mouse lines are generated and/or maintained on the C57BL/6J background, a strain where manipulation of anxiety-like behavior using benzodiazepines is difficult. Fear-potentiated startle (FPS), a test of conditioned fear, is a useful preclinical tool to study PTSD-like responses but has been difficult to establish in C57BL/6J mice. Methods We modified several FPS experimental parameters and developed a paradigm to assess conditioned fear in C57BL/6J mice. The 6-day protocol consisted of three startle Acclimation days, a Pre-Test day followed by Training and Testing for FPS. Subject responses to the effects of three benzodiazepines were also examined. Results C57BL/6J mice had low levels of unconditioned fear assessed during Pre-Test (15–18%) but showed robust FPS (80–120%) during the Test session. Conditioned fear responses extinguished over repeated test sessions. Administration of the benzodiazepines alprazolam (0.5 and 1 mg/kg, i.p.), chlordiazepoxide (5 and 10 mg/kg, i.p.), and diazepam (1, 2, and 4 mg/kg, i.p.) significantly reduced FPS to Pre-Test levels. Conclusions We used a modified and pharmacologically-validated paradigm to assess FPS in mice thereby providing a powerful tool to examine the neurobiology of PTSD in genetic models of anxiety generated on the C57BL/6J background. PMID:20922362

  18. First external quality assurance program of the Italian HLA-B*57:01 Network assessing the performance of clinical virology laboratories in HLA-B*57:01 testing.

    Science.gov (United States)

    Meini, Genny; Dello Russo, Cinzia; Allice, Tiziano; Barresi, Renata; D'Arrigo, Roberta; Falasca, Francesca; Lipsi, Maria Rosaria; Paolucci, Stefania; Zanussi, Stefania; Antonetti, Raffaele; Baldanti, Fausto; Basaglia, Giancarlo; Bruzzone, Bianca; Polilli, Ennio; Ghisetti, Valeria; Pucillo, Leopoldo Paolo; Turriziani, Ombretta; Pirazzoli, Antonella; Navarra, Pierluigi; Zazzi, Maurizio

    2016-05-01

    Since the HLA-B*57:01 allele is strongly associated with abacavir hypersensitivity reaction, testing for the presence of HLA-B*57:01 is mandatory before administration of abacavir. While HLA-B*57:01 testing is usually provided by pharmacogenetics, genetics or blood transfusion services, clinical virology laboratories can be an optimal opportunity for HLA-B*57:01 testing since they receive blood samples for routine HIV monitoring and have the expertise for convenient and less expensive PCR-based point mutation assays. The Italian HLA-B*57:01 Network gathers accredited clinical virology laboratories offering HLA-B*57:01 testing in Italy with the aim to share protocols, test new methods, develop and maintain external quality assurance (EQA) programs. A panel of 9HLA-B*57:01-positive and 16HLA-B*57:01-negative frozen blood samples were blindly distributed to 10 units including 9 clinical virology laboratories and one reference pharmacology laboratory. Each laboratory was free to use its own routine method for DNA extraction and HLA-B*57:01 testing. DNA was extracted by automated workstations in 6 units and by manual spin columns in 4. Eight units used the Duplicα Real Time HLA-B*57:01 kit by Euroclone and two units used two different PCR homemade protocols. All the 10 units correctly identified all the 25 samples. The first HLA-B*57:01 EQA program run in Italy showed that clinical virology units are equipped and proficient for providing HLA-B*57:01 testing by inexpensive assays easy to integrate into their routine. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Geological Map of the Fredegonade (V-57) Quadrangle, Venus: Status Report

    Science.gov (United States)

    Ivanov, M. A.; Head, J. W.

    2010-01-01

    The Fredegonde quadrangle (V-57; 50-75degS, 60-120degE, Fig. 1) corresponds to the northeastern edge of Lada Terra and covers a broad area of the topographic province of midlands (0-2 km above MPR [1,2]). This province is most abundant on Venus and displays a wide variety of units and structures [3-11]. The sequence of events that formed the characteristic features of the midlands is crucially important in understanding of the timing and modes of evolution of this topographic province. Topographically, the Fredegonde quadrangle is within a transition zone between the elevated portion of Lada Terra to the west (Quetzalpetlatl-Boala Coronae rise, approx.3.5 km) and the lowland of Aino Planitia to the north and northeast (approx.-0.5 km). This transition is one of the key features of the V-57 quadrangle. In this respect the quadrangle resembles the region of V-4 quadrangle [12] that shows transition between the midlands and the lowlands of Atalanta Planitia. One of the main goals of our mapping within the V-57 quadrangle is comparison of this region with the other transitional topographic zones such as quadrangles V-4 and V-3 [13]. The most prominent features in the V-57 quadrangle are linear deformational zones of grooves and large coronae. The zones characterize the central and NW portions of the map area and represent broad (up to 100s of km wide) ridges that are 100s of m high. Morphologically and topographically, these zones are almost identical to the groove belt/corona complexes at the western edge of Atalanta Planitia [12]. Within the Fredegonde area, however, the zones are oriented at high angles to the general trend of elongated Aino Planitia, whereas within the V-4 quadrangle they are parallel to the edge of Atalanta Planitia. Relatively small (100s of km across, 100s of m deep) equidimensional basins occur between the corona-groove-chains in the area of V-57 quadrangle. These basins are similar to those that populate the area of the V-3 quadrangle [13

  20. Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains.

    Science.gov (United States)

    Sims, Emily K; Hatanaka, Masayuki; Morris, David L; Tersey, Sarah A; Kono, Tatsuyoshi; Chaudry, Zunaira Z; Day, Kathleen H; Moss, Dan R; Stull, Natalie D; Mirmira, Raghavendra G; Evans-Molina, Carmella

    2013-12-01

    Impaired glucose tolerance (IGT) and type 2 diabetes (T2DM) are polygenic disorders with complex pathophysiologies; recapitulating them with mouse models is challenging. Despite 70% genetic homology, C57BL/6J (BL6) and C57BLKS/J (BLKS) inbred mouse strains differ in response to diet- and genetic-induced obesity. We hypothesized these differences would yield insight into IGT and T2DM susceptibility and response to pharmacological therapies. To this end, male 8-wk-old BL6 and BLKS mice were fed normal chow (18% kcal from fat), high-fat diet (HFD; 42% kcal from fat), or HFD supplemented with the PPARγ agonist pioglitazone (PIO; 140 mg PIO/kg diet) for 16 wk. Assessments of body composition, glucose homeostasis, insulin production, and energy metabolism, as well as histological analyses of pancreata were undertaken. BL6 mice gained weight and adiposity in response to HFD, leading to peripheral insulin resistance that was met with increased β-cell proliferation and insulin production. By contrast, BLKS mice responded to HFD by restricting food intake and increasing activity. These behavioral responses limited weight gain and protected against HFD-induced glucose intolerance, which in this strain was primarily due to β-cell dysfunction. PIO treatment did not affect HFD-induced weight gain in BL6 mice, and decreased visceral fat mass, whereas in BLKS mice PIO increased total fat mass without improving visceral fat mass. Differences in these responses to HFD and effects of PIO reflect divergent human responses to a Western lifestyle and underscore the careful consideration needed when choosing mouse models of diet-induced obesity and diabetes treatment.

  1. ZFP57 recognizes multiple and closely spaced sequence motif variants to maintain repressive epigenetic marks in mouse embryonic stem cells.

    Science.gov (United States)

    Anvar, Zahra; Cammisa, Marco; Riso, Vincenzo; Baglivo, Ilaria; Kukreja, Harpreet; Sparago, Angela; Girardot, Michael; Lad, Shraddha; De Feis, Italia; Cerrato, Flavia; Angelini, Claudia; Feil, Robert; Pedone, Paolo V; Grimaldi, Giovanna; Riccio, Andrea

    2016-02-18

    Imprinting Control Regions (ICRs) need to maintain their parental allele-specific DNA methylation during early embryogenesis despite genome-wide demethylation and subsequent de novo methylation. ZFP57 and KAP1 are both required for maintaining the repressive DNA methylation and H3-lysine-9-trimethylation (H3K9me3) at ICRs. In vitro, ZFP57 binds a specific hexanucleotide motif that is enriched at its genomic binding sites. We now demonstrate in mouse embryonic stem cells (ESCs) that SNPs disrupting closely-spaced hexanucleotide motifs are associated with lack of ZFP57 binding and H3K9me3 enrichment. Through a transgenic approach in mouse ESCs, we further demonstrate that an ICR fragment containing three ZFP57 motif sequences recapitulates the original methylated or unmethylated status when integrated into the genome at an ectopic position. Mutation of Zfp57 or the hexanucleotide motifs led to loss of ZFP57 binding and DNA methylation of the transgene. Finally, we identified a sequence variant of the hexanucleotide motif that interacts with ZFP57 both in vivo and in vitro. The presence of multiple and closely located copies of ZFP57 motif variants emerges as a distinct characteristic that is required for the faithful maintenance of repressive epigenetic marks at ICRs and other ZFP57 binding sites. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  2. Infant behaviors are predictive of functional somatic symptoms at ages 5-7 years

    DEFF Research Database (Denmark)

    Rask, Charlotte Ulrikka; Ørnbøl, Eva; Olsen, Else Marie

    2013-01-01

    health, development, and functioning were assessed by community health nurses at 4 home visits from birth to age 10 months. FSS at ages 5-7 years were measured by the Soma Assessment Interview in 1327 children. Sociodemographic data and information on maternal psychiatric illness were obtained from...... the Danish National Registers. RESULTS: Multiple logistic regression analysis controlled for maternal psychiatric illness and annual household income revealed that combined infancy regulatory problems (ie, at least 2 of 3 problems of feeding, sleeping, or tactile reactivity during the first 10 months...... of living) predicted impairing FSS at 5-7 years (aOR = 2.9, 95% CI: 1.3-6.6). Maternal psychiatric illness during the child's first year of living was also associated with later child FSS (aOR = 7.1, 95% CI: 1.8-27.8). CONCLUSION: Regulatory problems may be an early marker of disturbed sensory reactivity...

  3. Confirmation test of suspected Mycobacterium avium subspecies paratuberculosis (MAP isolated using PCR F57

    Directory of Open Access Journals (Sweden)

    Widagdo Sri Nugroho

    2008-06-01

    Full Text Available Seropositive and isolate suspected as Mycobacterium avium subspecies paratuberculosis (MAP was detected at dairy cows in West Java. This bacteria causes Johne’s disease (JD and potentially becomes a new emerging disease for Indonesian dairy cows. The aim of this study was to confirm the suspected local isolate as a MAP distinctively by PCR. Reculture of MAP reference isolate, suspected local isolate done by resuspending bacteria in PBS 0.5% and inoculating it in Herrold’s egg yolk medium with mycobactin J (HEYM and than inoculating it in 37oC for 16 weeks. The cultures grew in various time, Mycobacterium avium subspecies avium was detected in 3rd week, MAP reference was detected in 7th week, and local isolate was detected in 14th week. The confirmation test was carried out by PCR with primer F57. The PCR F57 result showed that MAP suspected isolate was not a Mycobacterium avium subspecies paratuberculosis.

  4. Dynamical Properties of 57Fe Dissolved in Al Observed by Mössbauer Effect

    DEFF Research Database (Denmark)

    Sørensen, K.; Trumpy, Georg

    1973-01-01

    The Mössbauer effect of 57Fe in aluminum was measured over the temperature range 20-642°C, using a source specimen of aluminum with 57Co in solid solution. The line-broadening values were converted to diffusion constants, which can be expressed by the temperature dependence D=0.12e-(1.4 eV) / kT cm...... broadening might be more accurate than the one used heretofore. Earlier determinations of the second-order Doppler shift were extended almost to the melting point of aluminum. The shift depends almost linearly on temperature, with the slope given by the Dulong—Petit rule for the heat capacity. From...... the temperature dependence of the Lamb—Mössbauer factor an effective Debye temperature of (210 ± 15)°K was found....

  5. Luminosity dependent accretion state change in GRO J1008–57

    Directory of Open Access Journals (Sweden)

    Kühnel Matthias

    2014-01-01

    Full Text Available In a former publication, we have analyzed the transient neutron star X-ray binary GRO J1008–57 using all available RXTE-, Swift-, and Suzaku-data. As we have found, the source’s spectral components, i.e., a power-law with high exponential cutoff and a black-body, are strongly correlated with the hard X-ray flux (15–50 keV. We update the analytical description of these dependence, including a change in the photon index behaviour from a flat to a logarithmic function. The flux, where the change occurs, is consistent with the onset of the black-body emission. Thus, a change of the accretion state always occurs in GRO J1008–57 at a particular flux level.

  6. Performance of new solid state {gamma}-detectors in {sup 57}Fe Moessbauer spectroscopy experiments

    Energy Technology Data Exchange (ETDEWEB)

    Dellmann, Til; Klauss, Hans-Henning [Institute of Solid State Physics, TU Dresden (Germany)

    2011-07-01

    Usually, proportional counter tubes are used in {sup 57}Fe Moessbauer spectroscopy for the detection of the 14.4 keV transition line. % and further signal processing. The recent developement of Si-based solid state detectors led to commercially available drift detectors (SDD) and high purity PiN diodes without the necessity of cooling with liquid nitrogen. First applications of SDD detectors in the analysis of minerals are already highly promising. In this talk, we present a detailed comparison between the three detector types and their use in Moessbauer spectroscopy using a standard absorber-source-combination (metallic iron with a 2.0 GBq {sup 57}Co/Rh source) in absorbtion geometry. Starting with the definition of a global efficiency function, which optimises the goodness of a Moessbauer spectrum and thus the required measurement time, we examined the influence of the intrinsic detector parameters on the global efficiency.

  7. Macrophages are mediators of gastritis in acute Helicobacter pylori infection in C57BL/6 mice.

    Science.gov (United States)

    Kaparakis, Maria; Walduck, Anna K; Price, Jason D; Pedersen, John S; van Rooijen, Nico; Pearse, Martin J; Wijburg, Odilia L C; Strugnell, Richard A

    2008-05-01

    Helicobacter pylori is the etiological agent of human chronic gastritis, a condition seen as a precursor to the development of gastrointestinal ulcers or gastric cancer. This study utilized the murine model of chronic H. pylori infection to characterize the role of macrophages in the induction of specific immune responses and gastritis and in the control of the bacterial burden following H. pylori infection and vaccination. Drug-loaded liposomes were injected intravenously to deplete macrophages from C57BL/6 mice, and effective removal of CD11b+ cells from the spleens and stomachs of mice was confirmed by immunofluorescence microscopy. Transient elimination of macrophages from C57BL/6 mice during the early period of infection reduced the gastric pathology induced by H. pylori SS1 but did not affect the bacterial load in the stomach. These data suggest that macrophages are important to the severity of gastric inflammation during H. pylori infection.

  8. Synthesis and Biological Evaluation of Novel 5,7-Dichloro-1,3-benzoxazole Derivatives

    Directory of Open Access Journals (Sweden)

    N. D. Jayanna

    2013-01-01

    Full Text Available A new class of 5,7-dichloro-1,3-benzoxazole derivatives 4–11 were synthesized by fusing 5,7-dichloro-2-hydrazino-1,3-benzoxazole 3 nucleus with aliphatic acids, active methylene compounds, and with selected esters to form heterocyclic ring systems like 1,2,4-triazoles, pyrazoles, and triazine moieties. The compound 3 on diazotization reaction affords the tetrazole compound. The synthesized compounds were characterized by 1H NMR, IR, Mass, and 13C NMR spectral data and screened for cytotoxic, antimicrobial, antioxidant, and antilipase activities. The compounds 4, 5, and 8 have shown significant antimicrobial activities, whereas compounds 6 and 8 have been emerged as leading cytotoxic agents. The compounds 9, 10, and 11 were found to be strong enzyme inhibitors.

  9. Hydrolyzed casein reduces diet-induced obesity in male C57BL/6J mice

    DEFF Research Database (Denmark)

    Lillefosse, Haldis Haukås; Tastesen, Hanne Sørup; Du, Zhen-Yu

    2013-01-01

    The digestion rate of dietary protein is a regulating factor for postprandial metabolism both in humans and animal models. However, few data exist about the habitual consumption of proteins with different digestion rates with regard to the development of body mass and diet-induced obesity. Here, we...... used a factorial ANOVA design to investigate the effects of protein form (intact vs. hydrolyzed casein) and protein level (16 vs. 32 energy percent protein) on body mass gain and adiposity in obesity-prone male C57BL/6J mice fed Western diets with 35 energy percent fat. Mice fed the hydrolyzed casein...... by hydrolyzed casein ingestion translated into decreased body and adipose tissue masses. We conclude that chronic consumption of extensively hydrolyzed casein reduces body mass gain and diet-induced obesity in male C57BL/6J mice....

  10. Report on neutron depolarisation measurements of C60 and 57Cr3 steel samples

    Energy Technology Data Exchange (ETDEWEB)

    Velthuis, S.G.E. te

    1995-12-01

    In this report initial measurements of C60 and 57Cr3 steel samples using neutron depolarization are discussed. During the experiments, the austenite to ferrite and perlite transformation was studied. The ferrite fraction formed and the mean ferrite particle radius were determined from the rotation and the shortening of the polarization vector of the neutron beam. Besides an overview of the performed experiments, the theoretical approach which was used to determine the transformation parameters, is described. (orig.).

  11. STS-57 MS2 Sherlock in EMU is lowered into JSC's WETF pool for EVA simulation

    Science.gov (United States)

    1992-01-01

    STS-57 Mission Specialist 2 (MS2) Nancy J. Sherlock, fully suited in an extravehicular mobility unit (EMU) and helmet and standing on a platform, is lowered into the 25 foot deep pool of JSC's Weightless Environment Training Facility (WETF) Bldg 29. Once underwater, Sherlock will participate in an underwater extravehicular activity (EVA) simulation. SCUBA-equipped divers already in the pool guide the platform into the water.

  12. Alleviation of experimental allergic encephalomyelitis in C57BL/6 mice by soy daidzein.

    OpenAIRE

    Soodeh Razeghi Jahromi; Seyed Rafi Arrefhosseini; Amir Ghaemi; Akram Alizadeh; Hedieh Moradi Tabriz; Mansoureh Togha

    2014-01-01

    Experimental allergic encephalomyelitis (EAE) is considered as the murine model of multiple sclerosis. Daidzein a phytostrogenic compound of soy is known to impose immunomodulatory and antioxidative effects. We conducted this study to assess the potential protective and therapeutic effects of daidzein on allergic encephalomyelitis.C57BL/6 mice were induced with allergic encephalomyelitis using myelin oligodendrocyte glycoprotein (35-55) and received daidzein or dimethyl sulfoxide as the vehic...

  13. Klimt artwork: material investigation by backscattering Fe-57 Mössbauer and Raman spectroscopy

    Science.gov (United States)

    Costa, B. F. O.; Blumers, M.; Sansano, A.; Klingelhöfer, G.; Rull, F.; Lehmann, R.; Renz, F.

    2014-04-01

    The long lost painting "Trumpeting Putto" was discovered and now is not only in the focus of art historian, but has also scientific interest too. We underwent this rare case of an inorganic layered artwork a non-destructive material investigation by employing Raman and MIMOSII Fe-57 Mössbauer spectroscopy. First results indicate several layers, where two layers of different pigments are on an inorganic background layer stabilised by a metallic wire within a wooden frame structure

  14. Mössbauer Emission-Spectra of Impurity Cobalt-57 in a Halide Matrix

    DEFF Research Database (Denmark)

    Maddock, A. G.; Williams, A. F.; Siekierska, K. E.

    1976-01-01

    The Mössbauer emission spectra of 57Co in low concentrations in KF, NaCl, NaF, LiF, and MgF2, and the effects of doping NaF and LiF with La3+ ions are reported. The monovalent halides all give similar spectra showing a broad single line or a doublet at 2.19mm/s and two overlapping doublets at 0...

  15. Blueberry and Mulberry Juice Prevent Obesity Development in C57BL/6 Mice

    OpenAIRE

    Tao Wu; Qiong Tang; Zichun Gao; Zhuoping Yu; Haizhao Song; Xiaodong Zheng; Wei Chen

    2013-01-01

    Objectives To establish whether blueberry (Vaccinium ashei) and mulberry (Morus australis Poir) juice, anthocyanin rich fruit juice, may help counteract obesity. Design And Methods: Four-week-old C57BL/6 mice were fed a high-fat diet (HFD) with or without blueberry and mulberry juice for 12 weeks. Body weight, serum and hepatic lipids, liver and adipose tissues morphology, insulin and leptin were assessed. Results Mice fed HFD exhibited increased body weight, insulin resistance, serum and hep...

  16. Evaluation of hematologic variables in newborn C57/BL6 mice up to day 35.

    Science.gov (United States)

    White, Jessica R; Gong, Huiyu; Colaizy, Tarah T; Moreland, Jessica G; Flaherty, Heather; McElroy, Steven J

    2016-03-01

    Hematologic variables are often analyzed in animal analogs during the investigation of complex disease etiologies such as necrotizing enterocolitis. However, reference intervals (RI) can vary depending on animal strain, age, and sampling site. Reference intervals have been published for adult C57BL/6J mice, but not newborn C57BL/6J mice. The purpose of the present study was to determine hematologic RI in newborn C57BL/6J mice up to day 35. C57BL/6J mice founders from The Jackson Laboratory were bred at the University of Iowa. Blood samples were obtained via facial vein sampling at postnatal days 0 (p0), p7, p14, p21, p28, or young adulthood (p35). CBCs were determined with the Sysmex XT-2000iV analyzer within 30 minutes of blood collection at a 1:10 dilution. Statistics were determined using nonparametric methods following ASVCP guidelines. Hematologic RI were determined for each of the 6 groups (n = 247, n ≥ 39 per group). Significantly higher values for HGB, RBC, and PLT counts were observed with advancing developmental age. Total WBC counts remained relatively stable during the first 35 days of life. However, WBC differential counts were dominated by neutrophils and lymphocytes in the younger mice, with a trend toward a lymphocytic leukogram on day 35. These results illustrate the dynamic changes in hematologic variables during murine development after birth. Utilization of age-specific RI is advised when evaluating data derived from experimental perinatal mouse models. © 2015 American Society for Veterinary Clinical Pathology.

  17. Evaluation of hematologic composition in newborn C57/BL6 mice up to day 35

    Science.gov (United States)

    White, Jessica R; Gong, Huiyu; Colaizy, Tarah; Moreland, Jessica G; Flaherty, Heather; McElroy, Steven J

    2015-01-01

    Background Hematologic variables are often analyzed in animal analogues during the investigation of complex disease etiologies such as necrotizing enterocolitis. However, reference intervals (RI) can vary depending on animal strain, age, and sampling site. Reference intervals have been published for adult C57BL/6J mice, but not newborn C57BL/6J mice. Objectives The purpose of the present study was to determine hematologic RI in newborn C57BL/6J mice up to day 35. Methods C57BL/6J mice founders from The Jackson Laboratory were bred at the University of Iowa. Blood samples were obtained via facial vein sampling at postnatal days 0 (p0), p7, p14, p21, p28, or young adulthood (p35). CBCs were determined with the Sysmex XT-2000iV analyzer within 30 minutes of blood collection at a 1:10 dilution. Statistics were determined using nonparametric methods following ASVCP guidelines. Results Hematologic RI were determined for each of the 6 groups (n=247, n≥39 per group). Significantly higher values for HGB, RBC, and PLT counts were observed with advancing developmental age. Total WBC counts remained relatively stable during the first 35 days of life. However, WBC differential counts were dominated by neutrophils and lymphocytes in the younger mice, with a trend towards a lymphocytic leukogram on day 35. Conclusions These results illustrate the dynamic changes in hematologic variables during murine development after birth. Utilization of age-specific RI is advised when evaluating data derived from experimental perinatal mouse models. PMID:26717267

  18. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA); Scientific Opinion on the substantiation of health claims related to a combination of Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C and defence against vaginal pathogens (ID 934, further assessment) pursuant to Article 13(1) of Regulation (EC) No 1924/2006.

    OpenAIRE

    Tetens, Inge

    2012-01-01

    Following a request from the European Commission, the Panel on Dietetic Products, Nutrition and Allergies was asked to provide a scientific opinion on a health claim pursuant to Article 13 of Regulation (EC) No 1924/2006 in the framework of further assessment related to a combination of Lactobacillus fermentum 57A, Lactobacillus plantarum 57B and Lactobacillus gasseri 57C and defence against vaginal pathogens. The food constituent that is the subject of the claim, a combination of Lactobacill...

  19. Lycopene pretreatment improves hepatotoxicity induced by acetaminophen in C57BL/6 mice.

    Science.gov (United States)

    Bandeira, Ana Carla Balthar; da Silva, Rafaella Cecília; Rossoni, Joamyr Victor; Figueiredo, Vivian Paulino; Talvani, André; Cangussú, Silvia Dantas; Bezerra, Frank Silva; Costa, Daniela Caldeira

    2017-02-01

    Acetaminophen (APAP) is an antipyretic and analgesic drug that, in high doses, leads to severe liver injury and potentially death. Oxidative stress is an important event in APAP overdose. Researchers are looking for natural antioxidants with the potential to mitigate the harmful effects of reactive oxygen species in different models. Lycopene has been widely studied for its antioxidant properties. The aim of this study was to evaluate the antioxidant potential of lycopene pretreatment in APAP-induced liver injury in C57BL/6 mice. C57BL/6 male mice were divided into the following groups: control (C); sunflower oil (CO); acetaminophen 500mg/kg (APAP); acetaminophen 500mg/kg+lycopene 10mg/kg (APAP+L10), and acetaminophen 500mg/kg+lycopene 100mg/kg (APAP+L100). Mice were pretreated with lycopene for 14 consecutive days prior to APAP overdose. Analyses of blood serum and livers were performed. Lycopene was able to improve redox imbalance, decrease thiobarbituric acid reactive species level, and increase CAT and GSH levels. In addition, it decreased the IL-1β expression and the activity of MMP-2. This study revealed that preventive lycopene consumption in C57BL/6 mice can attenuate the effects of APAP-induced liver injury. Furthermore, by improving the redox state, and thus indicating its potential antioxidant effect, lycopene was also shown to have an influence on inflammatory events. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. EXPERIMENTAL SUBCUTANEOUS CYSTICERCOSIS BY Taenia crassiceps IN BALB/c AND C57BL/6 MICE

    Directory of Open Access Journals (Sweden)

    Íria Márcia PEREIRA

    2016-01-01

    Full Text Available SUMMARY Human cysticercosis is one of the most severe parasitic infections affecting tissues. Experimental models are needed to understand the host-parasite dynamics involved throughout the course of the infection. The subcutaneous experimental model is the closest to what is observed in human cysticercosis that does not affect the central nervous system. The aim of this study was to evaluate macroscopically and microscopically the experimental subcutaneous cysticercosis caused by Taenia crassiceps cysticerci in BALB/c and C57BL/6 mice. Animals were inoculated in the dorsal subcutaneous region and macroscopic and microscopic aspects of the inflammatory process in the host-parasite interface were evaluated until 90 days after the inoculation (DAI. All the infected animals presented vesicles containing cysticerci in the inoculation site, which was translucent at 7 DAI and then remained opaque throughout the experimental days. The microscopic analysis showed granulation tissue in BALB/c mice since the acute phase of infection evolving to chronicity without cure, presenting 80% of larval stage cysticerci at 90 DAI. While C57BL/6 mice presented 67% of final stage cysticerci at 90 DAI, the parasites were surrounded by neutrophils evolving to the infection control. It is possible to conclude that the genetic features of susceptibility (BALB/c or resistance (C57BL/6 were confirmed in an experimental subcutaneous model of cysticercosis.

  1. Crystal and magnetic properties of 57Fe doped MnAs for magnetic refrigeration application

    Science.gov (United States)

    Lim, Jung Tae; Cho, Hyun Tae; Kim, Sam Jin; Kim, Chul Sung; Lee, Young Bae

    2017-11-01

    The Mn1- x 57Fe x As ( x = 0.001, 0.003, 0.005) compounds for magnetic refrigeration application were synthesized by using a solid-vapor reaction method. We have investigated the crystallographic and magnetic properties of Mn1- x 57Fe x As ( x = 0.001, 0.003, 0.005) samples by using x-ray diffractometer (XRD), vibrating sample magnetometer (VSM), superconducting quantum interference device (SQUID), and Mössbauer spectrometer. The XRD patterns, revealed that all samples exhibited hexagonal space group P63/ mmc below Curie temperature ( T C ), while above T C they belong to the orthorhombic space group Pnma. The temperature-dependent magnetization curves under 200 Oe between 4.2 and 320 K showed a large hysteresis in the magnetization as a function of the temperature. To analyze the meagnetocaloric effect, the value of magnetic entropy (-Δ S M ) was calculated from the isothermal initial curves up to 5 T at various temperatures. Mössbauer spectra of Mn0.997 57Fe0.003As sample were taken at various temperatures ranging from 4.2 to 315 K.

  2. Host resistance to primary and secondary Campylobacter jejuni infections in C57Bl/6 mice.

    Science.gov (United States)

    Vucković, Darinka; Abram, Maja; Bubonja, Marina; Wraber, Branka; Dorić, Miljenko

    2006-01-01

    Campylobacter jejuni has been known as a main causative agent of human enterocolitis for more than 30 years. This has prompted the research on defence mechanisms of the host involved. Although the humoral immune response to C. jejuni has been addressed in many studies, relatively little is known about the role of T lymphocytes in campylobacteriosis. The current study was based on in vivo T-cell subsets depletion to evaluate the role of CD4+ and CD8+ T lymphocytes in disseminated C. jejuni infection in C57BL/6 mice. Depletion of either CD8+ or CD4+ cells did not change the overall infection kinetics of primary campylobacteriosis. To assess the role of T cells in acquired immunity that develops during primary infection in C57BL/6 mice, in vivo depletions were performed during reinfection. Depletion of CD4+ cells did not have any effect on secondary infection kinetics, whereas depletion of CD8+ cells resulted in secondary liver infection that failed to resolve during the observed period. This study showed that both CD8+ and CD4+ T cells contribute to protection of C57BL/6 mice against C. jejuni. However, the predominant role resides in the CD8+ cell subpopulation. The exact mechanisms by which CD8+ cells operate during the course of campylobacteriosis will be the subject of our further research.

  3. Reparative myocardial mechanisms in adult C57BL/6 and MRL mice following injury.

    Science.gov (United States)

    Naseem, R Haris; Meeson, Annette P; Michael Dimaio, J; White, Michael D; Kallhoff, Justin; Humphries, Caroline; Goetsch, Sean C; De Windt, Leon J; Williams, Maurice A; Garry, Mary G; Garry, Daniel J

    2007-06-19

    Previous studies have suggested that the heart may be capable of limited repair and regeneration in response to a focal injury, while other studies indicate that the mammalian heart has no regenerative capacity. To further explore this issue, we performed a series of superficial and transmural myocardial injuries in C57BL/6 and MRL/MpJ adult mice. At defined time intervals following the respective injury (days 3, 14, 30 and 60), we examined cardiac function using echocardiography, morphology, fluorescence-activated cell sorting for 5-bromo-2-deoxyuridine-positive cells and molecular signature using microarray analysis. We observed restoration of myocardial function in the superficial MRL cryoinjured heart and significantly less collagen deposition compared with the injured hearts of C57BL/6 mice. Following a severe transmural myocardial injury, the MRL mouse has increased survival and decreased ventricular remodeling compared with the C57BL/6 mouse but without evidence of complete regeneration. The cytoprotective program observed in the severely injured MRL heart is in part due to increased cellular proliferation, increased vasculogenesis, and decreased apoptosis that limits the extension of the injury. We conclude that MRL injured hearts have evidence of myocardial regeneration, in response to superficial injury, but the stabilized left ventricular function and improved survival observed in the MRL mouse following severe injury is not associated with complete myocardial regeneration.

  4. Acute Oral Toxicity Study of GAL-57 (Bentazon + Dicamba Herbicide in Rats

    Directory of Open Access Journals (Sweden)

    Dragica Brkić

    2009-01-01

    Full Text Available An acute oral toxicity study of the herbicide GAL-57 (Avalon, a mixture of bentazon and dicamba as active ingredients, was conducted to assess its acute oral toxicity to rats, using a new method that has been used in the past several years (2001. Clinical observations were performed for all animals after different time intervals, and gross necropsy was performed at termination of examination. Clinical symptoms (decreased activity, prone position, abnormal limb position, decreased righting reflex, decreased grip and limb tone, decreased body and abdominal tone and dyspnoea from mild to marked degree were noted after administration of 2000 mg/kg. Animals were found dead 30 minutes to one hour after the treatment. GAL-57 did not cause any clinical sings at single 300 mg/kg bw dose. The physical condition and behaviour of animals were normal during the 14-day observation period. The acute oral LD-50 value of the GAL-57 proved to be between 300 and 2000 mg/kg body weight in rats and was ranked into Poison group III according to Serbian criteria, category 4 of the Global Harmonized Classification System and Category III of the EPA classification.

  5. The Fredegonde (V-57) Quadrangle, Venus: Characterization of the Venus Midlands

    Science.gov (United States)

    Ivanov, M. A.; Head, James W.

    2008-01-01

    The Fredegonde quadrangle (V-57, 50-75degS, 60-120degE) in the southern hemisphere of Venus represents a typical region of midlands (0-2 km above MPR). Midlands are the most widespread topographic province on Venus (approx.80%) and display the richest variety of features. Geological mapping in the V-57 quadrangle provides the possibility of defining and characterizing units that make up a region of midlands and to establish the general sequence of events there and thus address questions about the modes of formation and chronology of midlands on Venus. The map area is in contact with the uplands in the central portion of Lada Terra to the west and the lowlands of Aino Planitia to the northeast. This position also provides a transitional zone between the other two major topographic provinces, similar to that of the Meskhent Tessera (V-3) area. Here we report on the results of our mapping in the V-57 quadrangle, describe the major features, units, and structural assemblages exposed there, and outline the main episodes of geologic history.

  6. Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice

    Directory of Open Access Journals (Sweden)

    Hughes Lori A

    2005-11-01

    Full Text Available Abstract Background Analysis of an allelic series of point mutations in a gene, generated by N-ethyl-N-nitrosourea (ENU mutagenesis, is a valuable method for discovering the full scope of its biological function. Here we present an efficient gene-driven approach for identifying ENU-induced point mutations in any gene in C57BL/6J mice. The advantage of such an approach is that it allows one to select any gene of interest in the mouse genome and to go directly from DNA sequence to mutant mice. Results We produced the Cryopreserved Mutant Mouse Bank (CMMB, which is an archive of DNA, cDNA, tissues, and sperm from 4,000 G1 male offspring of ENU-treated C57BL/6J males mated to untreated C57BL/6J females. Each mouse in the CMMB carries a large number of random heterozygous point mutations throughout the genome. High-throughput Temperature Gradient Capillary Electrophoresis (TGCE was employed to perform a 32-Mbp sequence-driven screen for mutations in 38 PCR amplicons from 11 genes in DNA and/or cDNA from the CMMB mice. DNA sequence analysis of heteroduplex-forming amplicons identified by TGCE revealed 22 mutations in 10 genes for an overall mutation frequency of 1 in 1.45 Mbp. All 22 mutations are single base pair substitutions, and nine of them (41% result in nonconservative amino acid substitutions. Intracytoplasmic sperm injection (ICSI of cryopreserved spermatozoa into B6D2F1 or C57BL/6J ova was used to recover mutant mice for nine of the mutations to date. Conclusions The inbred C57BL/6J CMMB, together with TGCE mutation screening and ICSI for the recovery of mutant mice, represents a valuable gene-driven approach for the functional annotation of the mammalian genome and for the generation of mouse models of human genetic diseases. The ability of ENU to induce mutations that cause various types of changes in proteins will provide additional insights into the functions of mammalian proteins that may not be detectable by knockout mutations.

  7. 30 CFR 57.15007 - Protective equipment or clothing for welding, cutting, or working with molten metal.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Protective equipment or clothing for welding, cutting, or working with molten metal. 57.15007 Section 57.15007 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR METAL AND NONMETAL MINE SAFETY AND HEALTH SAFETY AND HEALTH STANDARDS...

  8. 30 CFR 817.57 - Hydrologic balance: Surface activities in or adjacent to perennial or intermittent streams.

    Science.gov (United States)

    2010-07-01

    ... adjacent to perennial or intermittent streams. 817.57 Section 817.57 Mineral Resources OFFICE OF SURFACE... activities in or adjacent to perennial or intermittent streams. (a)(1) Buffer requirement. Except as provided... feet, measured horizontally, of a perennial or intermittent stream, unless the regulatory authority...

  9. 30 CFR 57.14130 - Roll-over protective structures (ROPS) and seat belts for surface equipment.

    Science.gov (United States)

    2010-07-01

    ... belts for surface equipment. 57.14130 Section 57.14130 Mineral Resources MINE SAFETY AND HEALTH....14130 Roll-over protective structures (ROPS) and seat belts for surface equipment. (a) Equipment included. Roll-over protective structures (ROPS) and seat belts shall be installed on— (1) Crawler tractors...

  10. 22 CFR 41.57 - International cultural exchange visitors and visitors under the Irish Peace Process Cultural and...

    Science.gov (United States)

    2010-04-01

    ... visitors under the Irish Peace Process Cultural and Training Program Act (IPPCTPA). 41.57 Section 41.57... visitors and visitors under the Irish Peace Process Cultural and Training Program Act (IPPCTPA). (a... operation of the Irish Peace Process Cultural and Training Program (IPPCTP) which establishes at a minimum...

  11. 47 CFR 80.57 - Canada/U.S.A. channeling arrangement for VHF maritime public correspondence.

    Science.gov (United States)

    2010-10-01

    ... maritime public correspondence. 80.57 Section 80.57 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... and Supplementary Channels. The effective radiated power (ERP) must not exceed 60 watts. Antenna... paragraph (d)(5) of this section. (2) Inland Waters Local Channel. ERP must not exceed 8 watts with an...

  12. Genetic and epigenetic mutations affect the DNA binding capability of human ZFP57 in transient neonatal diabetes type 1.

    Science.gov (United States)

    Baglivo, Ilaria; Esposito, Sabrina; De Cesare, Lucia; Sparago, Angela; Anvar, Zahra; Riso, Vincenzo; Cammisa, Marco; Fattorusso, Roberto; Grimaldi, Giovanna; Riccio, Andrea; Pedone, Paolo V

    2013-05-21

    In the mouse, ZFP57 contains three classical Cys2His2 zinc finger domains (ZF) and recognizes the methylated TGC(met)CGC target sequence using the first and the second ZFs. In this study, we demonstrate that the human ZFP57 (hZFP57) containing six Cys2His2 ZFs, binds the same methylated sequence through the third and the fourth ZFs, and identify the aminoacids critical for DNA interaction. In addition, we present evidences indicating that hZFP57 mutations and hypomethylation of the TNDM1 ICR both associated with Transient Neonatal Diabetes Mellitus type 1 result in loss of hZFP57 binding to the TNDM1 locus, likely causing PLAGL1 activation. Copyright © 2013 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  13. Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways.

    Directory of Open Access Journals (Sweden)

    Brooke B Sahin

    2010-03-01

    Full Text Available The control of RNA stability is a key determinant in cellular gene expression. The stability of any transcript is modulated through the activity of cis- or trans-acting regulatory factors as well as cellular quality control systems that ensure the integrity of a transcript. As a result, invading viral pathogens must be able to subvert cellular RNA decay pathways capable of destroying viral transcripts. Here we report that the Kaposi's sarcoma-associated herpesvirus (KSHV ORF57 protein binds to a unique KSHV polyadenylated nuclear RNA, called PAN RNA, and protects it from degradation by cellular factors. ORF57 increases PAN RNA levels and its effects are greatest on unstable alleles of PAN RNA. Kinetic analysis of transcription pulse assays shows that ORF57 protects PAN RNA from a rapid cellular RNA decay process, but ORF57 has little effect on transcription or PAN RNA localization based on chromatin immunoprecipitation and in situ hybridization experiments, respectively. Using a UV cross-linking technique, we further demonstrate that ORF57 binds PAN RNA directly in living cells and we show that binding correlates with function. In addition, we define an ORF57-responsive element (ORE that is necessary for ORF57 binding to PAN RNA and sufficient to confer ORF57-response to a heterologous intronless beta-globin mRNA, but not its spliced counterparts. We conclude that ORF57 binds to viral transcripts in the nucleus and protects them from a cellular RNA decay pathway. We propose that KSHV ORF57 protein functions to enhance the nuclear stability of intronless viral transcripts by protecting them from a cellular RNA quality control pathway.

  14. Early chronic lead exposure reduces exploratory activity in young C57BL/6J mice.

    Science.gov (United States)

    Flores-Montoya, Mayra Gisel; Sobin, Christina

    2015-07-01

    Research has suggested that chronic low-level lead exposure diminishes neurocognitive function in children. Tests that are sensitive to behavioral effects at lowest levels of lead exposure are needed for the development of animal models. In this study we investigated the effects of chronic low-level lead exposure on exploratory activity (unbaited nose poke task), exploratory ambulation (open field task) and motor coordination (Rotarod task) in pre-adolescent mice. C57BL/6J pups were exposed to 0 ppm (controls), 30 ppm (low-dose) or 230 ppm (high-dose) lead acetate via dams' drinking water administered from birth to postnatal day 28, to achieve a range of blood lead levels (BLLs) from not detectable to 14.84 µg dl(-1) ). At postnatal day 28, mice completed behavioral testing and were killed (n = 61). BLLs were determined by inductively coupled plasma mass spectrometry. The effects of lead exposure on behavior were tested using generalized linear mixed model analyses with BLL, sex and the interaction as fixed effects, and litter as the random effect. BLL predicted decreased exploratory activity and no threshold of effect was apparent. As BLL increased, nose pokes decreased. The C57BL/6J mouse is a useful model for examining effects of early chronic low-level lead exposure on behavior. In the C57BL/6J mouse, the unbaited nose poke task is sensitive to the effects of early chronic low-level lead exposure. This is the first animal study to show behavioral effects in pre-adolescent lead-exposed mice with BLL below 5 µg dl(-1). Copyright © 2014 John Wiley & Sons, Ltd.

  15. Characteristics of IL-17 induction by Schistosoma japonicum infection in C57BL/6 mouse liver

    Science.gov (United States)

    Chen, Dianhui; Luo, Xueping; Xie, Hongyan; Gao, Zhiyan; Fang, Huilong; Huang, Jun

    2013-01-01

    Schistosomiasis japonica is a severe tropical disease caused by the parasitic worm Schistosoma japonicum. Among the most serious pathological effects of S. japonicum infection are hepatic lesions (cirrhosis and fibrosis) and portal hypertension. Interleukin-17 (IL-17) is a pro-inflammatory cytokine involved in the pathogenesis of many inflammatory and infectious conditions, including schistosomiasis. We infected C57BL/6 mice with S. japonicum and isolated lymphocytes from the liver to identify cell subsets with high IL-17 expression and release using flow cytometry and ELISA. Expression and release of IL-17 was significantly higher in hepatic lymphocytes from infected mice compared with control mice in response to both non-specific stimulation with anti-CD3 monoclonal antibody plus/anti-CD28 monoclonal antibody and PMA plus ionomycin. We then compared IL-17 expression in three hepatic T-cell subsets, T helper, natural killer T and γδT cells, to determine the major source of IL-17 during infection. Interleukin-17 was induced in all three subsets by PMA + ionomycin, but γδT lymphocytes exhibited the largest increase in expression. We then established a mouse model to further investigate the role of IL-17 in granulomatous and fibrosing inflammation against parasite eggs. Reducing IL-17 activity using anti-IL-17A antibodies decreased infiltration of inflammatory cells and collagen deposition in the livers of infected C57BL/6 mice. The serum levels of soluble egg antigen (IL) -specific IgGs were enhanced by anti-IL-17A monoclonal antibody blockade, suggesting that IL-17 normally serves to suppress this humoral response. These findings suggest that γδT cells are the most IL-17-producing cells and that IL-17 contributes to granulomatous inflammatory and fibrosing reactions in S. japonicum-infected C57BL/6 mouse liver. PMID:23551262

  16. Computational Analysis of a Wing Designed for the X-57 Distributed Electric Propulsion Aircraft

    Science.gov (United States)

    Deere, Karen A.; Viken, Jeffrey K.; Viken, Sally A.; Carter, Melissa B.; Wiese, Michael R.; Farr, Norma L.

    2017-01-01

    A computational study of the wing for the distributed electric propulsion X-57 Maxwell airplane configuration at cruise and takeoff/landing conditions was completed. Two unstructured-mesh, Navier-Stokes computational fluid dynamics methods, FUN3D and USM3D, were used to predict the wing performance. The goal of the X-57 wing and distributed electric propulsion system design was to meet or exceed the required lift coefficient 3.95 for a stall speed of 58 knots, with a cruise speed of 150 knots at an altitude of 8,000 ft. The X-57 Maxwell airplane was designed with a small, high aspect ratio cruise wing that was designed for a high cruise lift coefficient (0.75) at angle of attack of 0deg. The cruise propulsors at the wingtip rotate counter to the wingtip vortex and reduce induced drag by 7.5 percent at an angle of attack of 0.6deg. The unblown maximum lift coefficient of the high-lift wing (with the 30deg flap setting) is 2.439. The stall speed goal performance metric was confirmed with a blown wing computed effective lift coefficient of 4.202. The lift augmentation from the high-lift, distributed electric propulsion system is 1.7. The predicted cruise wing drag coefficient of 0.02191 is 0.00076 above the drag allotted for the wing in the original estimate. However, the predicted drag overage for the wing would only use 10.1 percent of the original estimated drag margin, which is 0.00749.

  17. The C57BL/6 genetic background confers cardioprotection in iron-overloaded mice

    Science.gov (United States)

    Musumeci, Marco; Maccari, Sonia; Sestili, Paola; Massimi, Alessia; Corritore, Elisa; Marano, Giuseppe; Catalano, Liviana

    2013-01-01

    Background Chronic transfusion therapy causes a progressive iron overload that damages many organs including the heart. Recent evidence suggests that L-type calcium channels play an important role in iron uptake by cardiomyocytes under conditions of iron overload. Given that beta-adrenergic stimulation significantly enhances L-type calcium current, we hypothesised that beta-adrenergic blocking drugs could reduce the deleterious effects of iron overload on the heart. Methods Iron overload was generated by intraperitoneal injections of iron dextran (1g/kg) administered once a week for 8 weeks in male C57bl/6 mice, while propranolol was administered in drinking water at the dose of 40 mg/kg/day. Cardiac function and ventricular remodelling were evaluated by echocardiography and histological methods. Results As compared to placebo, iron injection caused cardiac iron deposition. Surprisingly, despite iron overload, myocardial function and ventricular geometry in the iron-treated mice resulted unchanged as compared to those in the placebo-treated mice. Administration of propranolol increased cardiac performance in iron-overloaded mice. Specifically, as compared to the values in the iron-overloaded group, in iron-overloaded animals treated with propranolol left ventricular fractional shortening increased (from 31.6% to 44.2%, P =0.01) whereas left ventricular end-diastolic diameter decreased (from 4.1±0.1 mm to 3.5±0.1 mm, P =0.03). Propranolol did not alter cardiac systolic function or left ventricular sizes in the placebo group. Conclusions These results demonstrate that C57bl/6 mice are resistant to iron overload-induced myocardial injury and that treatment with propranolol is able to increase cardiac performance in iron-overloaded mice. However, since C57bl/6 mice were resistant to iron-induced injury, it remains to be evaluated further whether propranolol could prevent iron-overload cardiomyopathy. PMID:22790263

  18. Radio afterglow of the jetted tidal disruption event Swift J1644+57

    Directory of Open Access Journals (Sweden)

    Mimica P.

    2012-12-01

    Full Text Available The recent transient event Swift J1644+57 has been interpreted as resulting from a relativistic outflow, powered by the accretion of a tidally disrupted star onto a supermassive black hole. This discovery of a new class of relativistic transients opens new windows into the study of tidal disruption events (TDEs and offers a unique probe of the physics of relativistic jet formation and the conditions in the centers of distant quiescent galaxies. Unlike the rapidly-varying γ/X-ray emission from Swift J1644+57, the radio emission varies more slowly and is well modeled as synchrotron radiation from the shock interaction between the jet and the gaseous circumnuclear medium (CNM. Early after the onset of the jet, a reverse shock propagates through and decelerates the ejecta released during the first few days of activity, while at much later times the outflow approaches the self-similar evolution of Blandford and McKee. The point at which the reverse shock entirely crosses the earliest ejecta is clearly observed as an achromatic break in the radio light curve at t ≈ 10 days. The flux and break frequencies of the afterglow constrain the properties of the jet and the CNM, including providing robust evidence for a narrowly collimated jet. I briefly discuss the implications of Swift J1644+57 for the fraction of TDEs accompanied by relativistic jets; the physics of jet formation more broadly; and the prospects for detecting off-axis TDE radio emission, either via follow-up observations of TDE candidates discovered at other wavelengths or blindly with upcoming wide-field radio surveys. The radio rebrightening observed months after the onset of the jet remains a major unsolved mystery, the resolution of which may require considering a jet with more complex (temporal or angular structure.

  19. Seismic inference of 57 stars using full-length Kepler data sets

    Science.gov (United States)

    Creevey, Orlagh; Metcalfe, Travis S.; Salabert, David; Mathur, Savita; Schultheis, Mathias; García, Rafael A.; Thévenin, Frédéric; Bazot, Michaël; Xu, Haiying

    2017-10-01

    We present stellar properties of 57 stars from a seismic inference using full-length data sets from Kepler (mass, age, radius, distances). These stars comprise active stars, planet-hosts, solar-analogs, and binary systems. We validate the distances derived from the astrometric Gaia-Tycho solution. Ensemble analysis of the stellar properties reveals a trend of mixing-length parameter with the surface gravity and effective temperature. We derive a linear relationship with the seismic quantity ‹r02› to estimate the stellar age. Finally, we define the stellar regimes where the Kjeldsen et al (2008) empirical surface correction for 1D model frequencies is valid.

  20. STS-57 MS2 Sherlock with HFA-EPROC laptop computer in SPACEHAB-01 module

    Science.gov (United States)

    1993-01-01

    STS-57 Mission Specialist 2 (MS2) Nancy J. Sherlock, positioned in front of SPACEHAB-01 (Commercial Middeck Augmentation Module (CMAM)) aft lockers, enters data on a portable laptop computer in conjunction with Human Factors Assessment (HFA) Electronic Procedures (EPROC) experiment. Computer portion of HFA-EPROC simulated a space station propulsion system task. HFA-EPROC is sponsored by Crew Interface Analysis Section, Flight Crew Support Division, Space and Life Sciences Directorate, JSC. Working in the background in the shirt-sleeve environment of SPACEHAB-01 is Pilot Brian J. Duffy. SPACEHAB-01 is located in the payload bay (PLB) of the Earth-orbiting Endeavour, Orbiter Vehicle (OV) 105.

  1. STS-57 MS2 Sherlock dons EMU upper torso with technicians' help at JSC's WETF

    Science.gov (United States)

    1992-01-01

    STS-57 Mission Specialist 2 (MS2) Nancy J. Sherlock, wearing the liquid cooling and ventilation garment (LCVG) and an extravehicular mobility unit (EMU) lower torso, squats under the EMU upper torso and prepares to raise her arms into the sleeves. Technicians stand on either side of Sherlock and are ready to assist her in donning the upper torso. When fully suited the platform Sherlock is on will be lowered into the 25 foot deep pool located in JSC's Weightless Environment Training Facility (WETF) Bldg 29. During the underwater simulation, Sherlock will practice extravehicular activity (EVA) procedures.

  2. 40 CFR Appendix A to Part 57 - Primary Nonferrous Smelter Order (NSO) Application

    Science.gov (United States)

    2010-07-01

    ..., materials and energy consumption per unit of output, yield rates and other physical input/output... 6.4 6.7 7.0 Energy prices: Electricity 7.0 8.8 8.1 8.3 7.1 4.9 5.5 Natural gas 3.6 5.7 9.3 8.7 9.2 8... charges and on the differential value of copper in the U.S. and the world market. They must be used in...

  3. Pulmonary manifestations of wegener granulomatosis: CT findings in 57 patients and a review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Lohrmann, Christian; Uhl, Markus; Kotter, Elmar; Burger, Dieter; Ghanem, Nadir; Langer, Mathias

    2005-03-01

    Wegener granulomatosis is a multisystem disease of unknown cause characterized by a necrotizing granulomatous vasculitis. In comparison to other vasculitides, the lung is the most common organ involved in wegener granulomatosis presenting with a very aggressive airways pathology and chronic relapsing course. Chest radiographs fail to describe the pattern and distribution of thoracic pathology sufficiently, and CT has shown to be more sensitive for detecting lung involvement. We present the CT findings of 57 patients with wegener granulomatosis and a review of the literature.

  4. Antiatherogenic effects of structured lipid containing conjugated linoleic acid in C57BL/6J mice.

    Science.gov (United States)

    Lee, Jeung Hee; Cho, Kyung Hyun; Lee, Ki-Teak; Kim, Mee Ree

    2005-09-07

    Conjugated linoleic acids (CLA) were enzymatically acidolyzed with olive oil to produce structured lipids (SL), and their antiatherosclerotic properties were investigated in C57BL/6J mice. Twenty-eight mice were divided into four groups and fed control diet or atherogenic diets supplemented with high cholesterol and high fat (HCHF) containing 5% of lard, olive oil, or SL based on control diet for 4 weeks. The supplementation of SL diet (0.6% CLA) significantly reduced the levels of serum total cholesterol and total triglyceride and increased high-density lipoprotein cholesterol level as compared to lard and olive oil diet groups (p atheroscelerosis.

  5. Variations of 57Fe hyperfine parameters in medicaments containing ferrous fumarate and ferrous sulfate

    Science.gov (United States)

    Oshtrakh, M. I.; Novikov, E. G.; Dubiel, S. M.; Semionkin, V. A.

    2010-04-01

    Several commercially available medicaments containing ferrous fumarate (FeC4H2O4) and ferrous sulfate (FeSO4), as a source of ferrous iron, were studied using a high velocity resolution Mössbauer spectroscopy. A comparison of the 57Fe hyperfine parameters revealed small variations for the main components in both medicaments indicating some differences in the ferrous fumarates and ferrous sulfates. It was also found that all spectra contained additional minor components probably related to ferrous and ferric impurities or to partially modified main components.

  6. The calculation and evaluation for n+54,56,57,58Fe reactions

    Science.gov (United States)

    Han, Yinlu; Xu, Yongli; Guo, Hairui; Zhang, Zhengjun; Liang, Haiying; Cai, Chonghai; Shen, Qingbiao

    2017-09-01

    All cross sections of neutron-induced reactions, angular distributions, double differential cross sections, angle-integrated spectra, γ-ray production cross sections and energy spectra for 54,56,57,58Fe are calculated by using theoretical models at incident neutron energies from 0.1 to 200 MeV. The present consistent theoretical calculated results are in good agreement with recent experimental data. The present evaluated data are compared with the existing experimental data and evaluated results from ENDF/B-VII, JENDL-4, JEFF-3, and the results are given in ENDF/B format.

  7. A single Alal 39-to-Glu substitution in the Renibacterium salmoninarum virulence-associated protein p57 results in antigenic variation and is associated with enhanced p57 binding to Chinook salmon leukocytes

    Science.gov (United States)

    Wiens, Gregory D.; Pascho, Ron; Winton, James R.

    2002-01-01

    The gram-positive bacterium Renibacterium salmoninarum produces relatively large amounts of a 57-kDa protein (p57) implicated in the pathogenesis of salmonid bacterial kidney disease. Antigenic variation in p57 was identified by using monoclonal antibody 4C11, which exhibited severely decreased binding to R. salmoninarum strain 684 p57 and bound robustly to the p57 proteins of seven other R. salmoninarum strains. This difference in binding was not due to alterations in p57 synthesis, secretion, or bacterial cell association. The molecular basis of the 4C11 epitope loss was determined by amplifying and sequencing the two identical genes encoding p57, msa1 and msa2. The 5′ and coding sequences of the 684 msa1 and msa2 genes were identical to those of the ATCC 33209 msa1and msa2 genes except for a single C-to-A nucleotide mutation. This mutation was identified in both the msa1 and msa2 genes of strain 684 and resulted in an Ala139-to-Glu substitution in the amino-terminal region of p57. We examined whether this mutation in p57 altered salmonid leukocyte and rabbit erythrocyte binding activities. R. salmoninarum strain 684 extracellular protein exhibited a twofold increase in agglutinating activity for chinook salmon leukocytes and rabbit erythrocytes compared to the activity of the ATCC 33209 extracellular protein. A specific and quantitative p57 binding assay confirmed the increased binding activity of 684 p57. Monoclonal antibody 4C11 blocked the agglutinating activity of the ATCC 33209 extracellular protein but not the agglutinating activity of the 684 extracellular protein. These results indicate that the Ala139-to-Glu substitution altered immune recognition and was associated with enhanced biological activity of R. salmoninarum 684 p57.

  8. HLA-B*57:01 allele prevalence in HIV-infected North American subjects and the impact of allele testing on the incidence of abacavir-associated hypersensitivity reaction in HLA-B*57:01-negative subjects.

    Science.gov (United States)

    Small, Catherine Butkus; Margolis, David A; Shaefer, Mark S; Ross, Lisa L

    2017-04-11

    The presence of the HLA-B*57:01 allele in HIV-infected subjects is associated with a higher risk of abacavir-associated hypersensitivity reaction (ABC HSR). HLA-B*57:01 allele prevalence varies in different populations, but HLA-B*57:01 testing with immunological confirmation has had a negative predictive value for ABC HSR between 97 and 100%. In the ASSURE study (EPZ113734), the HLA-B*57:01 prevalence in virologically suppressed, antiretroviral treatment-experienced, HIV-infected subjects from the United States, including Puerto Rico, was assessed. Three hundred eighty-five subjects were screened; 13 were HLA-B*57:01 positive and 372 were negative. Only HLA-B*57:01-negative, abacavir-naive subjects were eligible to enroll into the ASSURE trial. Eleven of the 13 subjects who possessed the HLA-B*57:01 allele were white, the other 2 were African-American. There was no geographic clustering of HLA-B*57:01-positive subjects, and the incidence correlated roughly with those states with the greatest numbers of subjects screened. Similarly, there was no statistically significant correlation between subjects who possessed or lacked the allele and age, gender, ethnicity or CD4+ T-cell numbers. The incidence of ABC HSR following abacavir initiation was also evaluated. Only 1 of 199 HLA-B*57:01-negative subjects (an African-American male) randomized to receive abacavir-containing treatment developed symptoms consistent with suspected ABC HSR; ABC HSR was not immunologically confirmed. These findings confirm the utility of HLA-B*57:01 allele testing to reduce the frequency of ABC HSR. The prevalence of HLA-B*57:01 positivity was higher in white than in African-American subjects. In HLA-B*57:01-negative subjects, suspected ABC HSR is very rare, but should lead to discontinuation of abacavir when ABC HSR cannot be definitively excluded from the differential diagnosis. The ASSURE (EPZ113734) study was registered on ClinicalTrials.gov registration on April 8th 2010 and the

  9. Protein Disulphide Isomerases: emerging roles of PDI and ERp57 in the nervous system and as therapeutic targets for ALS.

    Science.gov (United States)

    Perri, Emma; Parakh, Sonam; Atkin, Julie

    2017-01-01

    There is increasing evidence that endoplasmic reticulum (ER) chaperones Protein Disulphide Isomerase (PDI) and ERp57 (endoplasmic reticulum protein 57) are protective against neurodegenerative diseases related to protein misfolding, including Amyotrophic Lateral Sclerosis (ALS). PDI and ERp57 also possess disulphide interchange activity, in which protein disulphide bonds are oxidized, reduced and isomerized, to form their native conformation. Recently, missense and intronic variants of PDI and ERp57 were associated with ALS, implying that PDI proteins are relevant to ALS pathology. Areas covered: Here, we discuss possible implications of the PDI and ERp57 variants, as well as recent studies describing previously unrecognized roles for PDI and ERp57 in the nervous system. Therapeutics based on PDI may therefore be attractive candidates for ALS. However, in addition to its protective functions, aberrant, toxic roles for PDI have recently been described. These functions need to be fully characterized before effective therapeutic strategies can be designed. Expert opinion: These disease-associated variants of PDI and ERp57 provide additional evidence for an important role for PDI proteins in ALS. However, there are many questions remaining unanswered that need to be addressed before the potential of the PDI family in relation to ALS can be fully realized.

  10. The Effector Cig57 Hijacks FCHO-Mediated Vesicular Trafficking to Facilitate Intracellular Replication of Coxiella burnetii.

    Science.gov (United States)

    Latomanski, Eleanor A; Newton, Patrice; Khoo, Chen Ai; Newton, Hayley J

    2016-12-01

    Coxiella burnetii is an intracellular bacterial pathogen that infects alveolar macrophages and replicates within a unique lysosome-derived vacuole. When Coxiella is trafficked to a host cell lysosome the essential Dot/Icm type IV secretion system is activated allowing over 130 bacterial effector proteins to be translocated into the host cytosol. This cohort of effectors is believed to manipulate host cell functions to facilitate Coxiella-containing vacuole (CCV) biogenesis and bacterial replication. Transposon mutagenesis has demonstrated that the Dot/Icm effector Cig57 is required for CCV development and intracellular replication of Coxiella. Here, we demonstrate a role for Cig57 in subverting clathrin-mediated traffic through its interaction with FCHO2, an accessory protein of clathrin coated pits. A yeast two-hybrid screen identified FCHO2 as a binding partner of Cig57 and this interaction was confirmed during infection using immunoprecipitation experiments. The interaction between Cig57 and FCHO2 is dependent on one of three endocytic sorting motif encoded by Cig57. Importantly, complementation analysis demonstrated that this endocytic sorting motif is required for full function of Cig57. Consistent with the intracellular growth defect in cig57-disrupted Coxiella, siRNA gene silencing of FCHO2 or clathrin (CLTC) inhibits Coxiella growth and CCV biogenesis. Clathrin is recruited to the replicative CCV in a manner that is dependent on the interaction between Cig57 and FCHO2. Creation of an FCHO2 knockout cell line confirmed the importance of this protein for CCV expansion, intracellular replication of Coxiella and clathrin recruitment to the CCV. Collectively, these results reveal Cig57 to be a significant virulence factor that co-opts clathrin-mediated trafficking, via interaction with FCHO2, to facilitate the biogenesis of the fusogenic Coxiella replicative vacuole and enable intracellular success of this human pathogen.

  11. Outbred CD1 mice are as suitable as inbred C57BL/6J mice in performing social tasks.

    Science.gov (United States)

    Hsieh, Lawrence S; Wen, John H; Miyares, Laura; Lombroso, Paul J; Bordey, Angélique

    2017-01-10

    Inbred mouse strains have been used preferentially for behavioral testing over outbred counterparts, even though outbred mice reflect the genetic diversity in the human population better. Here, we compare the sociability of widely available outbred CD1 mice with the commonly used inbred C57BL/6J (C57) mice in the one-chamber social interaction test and the three-chamber sociability test. In the one-chamber task, intra-strain pairs of juvenile, non-littermate, male CD1 or C57 mice display a series of social and aggressive behaviors. While CD1 and C57 pairs spend equal amount of time socializing, CD1 pairs spend significantly more time engaged in aggressive behaviors than C57 mice. In the three-chamber task, sociability of C57 mice was less dependent on acclimation paradigms than CD1 mice. Following acclimation to all three chambers, both groups of age-matched male mice spent more time in the chamber containing a stranger mouse than in the empty chamber, suggesting that CD1 mice are sociable like C57 mice. However, the observed power suggests that it is easier to achieve statistical significance with C57 than CD1 mice. Because the stranger mouse could be considered as a novel object, we assessed for a novelty effect by adding an object. CD1 mice spend more time in the chamber with a stranger mouse than that a novel object, suggesting that their preference is social in nature. Thus, outbred CD1 mice are as appropriate as inbred C57 mice for studying social behavior using either the single or the three-chamber test using a specific acclimation paradigm. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  12. Susceptibility to hippocampal kindling seizures is increased in aging C57 black mice

    Directory of Open Access Journals (Sweden)

    Kurt R. Stover

    2017-12-01

    Full Text Available The incidence of seizures increases with old age. Stroke, dementia and brain tumors are recognized risk factors for new-onset seizures in the aging populations and the incidence of these conditions also increased with age. Whether aging is associated with higher seizure susceptibility in the absence of the above pathologies remains unclear. We used classic kindling to explore this issue as the kindling model is highly reproducible and allows close monitoring of electrographic and motor seizure activities in individual animals. We kindled male young and aging mice (C57BL/6 strain, 2–3 and 18–22 months of age via daily hippocampal CA3 stimulation and monitored seizure activity via video and electroencephalographic recordings. The aging mice needed fewer stimuli to evoke stage-5 motor seizures and exhibited longer hippocampal afterdischarges and more frequent hippocampal spikes relative to the young mice, but afterdischarge thresholds and cumulative afterdischarge durations to stage 5 motor seizures were not different between the two age groups. While hippocampal injury and structural alterations at cellular and micro-circuitry levels remain to be examined in the kindled mice, our present observations suggest that susceptibility to hippocampal CA3 kindling seizures is increased with aging in male C57 black mice.

  13. Fructus panax ginseng extract promotes hair regeneration in C57BL/6 mice.

    Science.gov (United States)

    Park, Soojin; Shin, Weon-Sun; Ho, Jinnyoung

    2011-11-18

    Radix panax ginseng (Panax ginseng C.A. Meyer, Araliaceae, RPG) has been documented to possess hair growth activity and widely used to treat alopecia, while no report has been issued to date on the effect of Fructus panax ginseng (FPG) on hair regeneration. To investigate the effects of FPG extract on the proliferation of human hair dermal papilla cells (DPCs) and on the promotion of hair regeneration in C57BL6 mice, cell proliferation was evaluated in cultured DPC by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) and measured the expressions of Bcl-2 and Bax by immunoblot assay. We also compared the effects of topical FPG extract (1 and 10 mg/ml, 100 μl/d) with the effects of minoxidil as a positive control (5%, 100 μl/d) or vehicle control (30% ethanol) on the depilation-induced hair cycling in 7 week-old-C57BL/6 mice. FPG extract significantly increased the proliferation of DPCs in dose and time dependent manners (Pregeneration activity for the treatment of hair loss. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  14. Project 57 Air Monitoring Annual Report - Fiscal Year 2013 (October 1, 2012 to September 30, 2013)

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Julianne J. [DRI; McCurdy, Greg [DRI; Mizell, Steve A [DRI

    2014-07-01

    The U.S. Department of Energy (DOE), National Nuclear Security Administration, Nevada Field Office (NNSA/NFO) is currently working to achieve regulatory closure of radionuclide-contaminated Soils sites under its auspices. Corrective Action Unit (CAU) 415, Project 57 No. 1 Plutonium Dispersion Site is located in Emigrant Valley, Nevada, on Range 4808A of the Nevada Test and Training Range (NTTR), and consists of one Corrective Action Site (CAS): NAFR-23-02, Pu Contaminated Soil. Closure plans being developed for the CAUs both on and off of the Nevada National Security Site (NNSS) may include postclosure monitoring for the possible release of radioactive contaminants. Determining the potential for transport of radionuclide-contaminated soils under ambient climatic conditions will facilitate an appropriate closure design and postclosure monitoring program. The DOE has authorized the Desert Research Institute (DRI) to conduct field assessments of potential transport of radionuclide-contaminated soil from the Project 57 site during ambient wind events. The assessment is intended to provide site-specific information on meteorological conditions that result in airborne soil particle redistribution, as well as determine which, if any, radiological contaminants may be entrained with the soil particles and estimate their concentrations.

  15. Examination of Mutagenic Effects of GAL-57 Herbicide (Bentazone+Dicamba Using Mouse Micronucleus Test

    Directory of Open Access Journals (Sweden)

    Vesela Karan

    2007-01-01

    Full Text Available A micronucleus test was run to investigate mutagenic potential of the herbicide GAL-57, a formulated mixture of bentazone and dicamba.The test was applied to mice of both sexes (strain: CRL: NMRI BR and the herbicide (product was administered by gavage at 2000 mg/kg rate, twice within 24 hs. Cyclophosphamide (positive control was administered at 60 mg/kg, while distilled water as a solvent was negative control. The animals were sacrificed 24 hs after second treatment, their bone marrow cells isolated from femur, and effects evaluated.The data acquired showed that repeated treatment of mice with GAL-57 caused neither biological nor significant statistical increase in the number of micronuclei in treated animals. At the same time, the number of micronucleated polychromatic erythrocytes in the bone marrow of animals treated with cyclophosphamide (positive control showed a significant statistical increase. The results suggest that the herbicide product tested did not show any mutagenic activity under the conditions of mouse micronucleus test.

  16. Histamine prevents polyamine accumulation in mouse C57.1 mast cell cultures.

    Science.gov (United States)

    Fajardo, I; Urdiales, J L; Paz, J C; Chavarría, T; Sánchez-Jiménez, F; Medina, M A

    2001-02-01

    The effects of histamine on polyamine uptake and metabolism was studied in a mouse mast cell line (C57.1), as a cell model in which both biogenic amines are important for maintaining cell function and viability. Results obtained after incubations with exogenous histamine indicated that histamine prevents polyamine accumulation by affecting polyamine uptake. A plasma membrane transport system for polyamines has been also studied in mast cells. It seems to be a Na(+)-dependent uptake with high affinity for both spermine and spermidine and lower affinity for putrescine and agmatine. Polyamine uptake was reduced in both cells treated with exogenous histamine and histamine-preloaded cells. However, ornithine decarboxylase activity and cell proliferation were not affected by histamine. Incubation with histamine enhanced the spermidine/spermine acetyl transferase induction caused by N(1)-ethyl-N(11)-[(cyclopropyl)methyl]-4,8-diazaundecane, suggesting that polyamine acetylation could be another mechanism by which histamine prevents polyamine accumulation in C57.1 mast cells.

  17. Effect of BNCT in hairless mouse and C57BL/6 mouse induced skin cancer

    Energy Technology Data Exchange (ETDEWEB)

    Chun, K. J.; Yu, B. K. [KAERI , Taejon (Korea, Republic of)

    2004-07-01

    We have carried out animal experiment with neutron irradiation since the completion of BNCT facility at HANARO research reactor recently. As a preliminary test regarding BNCT, skin cancer in hairless mouse was induced using two chemicals ; DMBA as an initiator and TPA as a promotor. Two chemicals were spreaded on the back below the head once a day during 15 weeks. Also skin cancer in C57BL/6 mouse was induced by transplanting with B-16 melanoma cells on the back below the head. BPA was administered by i.p injection with a dose of 750mg/kg body wt. 3hrs before irradiation and then BSH was administered by tail vein injection with a dose of 75mg/kg body wt. 1hr before irradiation. Neutrons were irradiated for 40 minutes in the BNCT facility. After that, we observed the cancer size with naked eyes and measured the size of it with ruler during the experimental period. BNCT treatment resulted in a decrease in the cancer size in the hairless mouse. However, the cancer in the C57BL/6 mouse did not show a decrease in size, even though it was smaller than that of the control. These results will make a great role for preclinical and clinical trials of BNCT. If the experiment is done in combination with various factors, better results can be obtained.

  18. Home improvement: C57BL/6J mice given more naturalistic nesting materials build better nests.

    Science.gov (United States)

    Hess, Sarah E; Rohr, Stephanie; Dufour, Brett D; Gaskill, Brianna N; Pajor, Edmond A; Garner, Joseph P

    2008-11-01

    Environmental enrichment of laboratory mice can improve the quality of research, but debate arises over the means of enrichment and its ability to be used in a sterile environment. One important form of enrichment is nesting material. Mice in the wild build dome-shaped, complex, multilayered nests, but this behavior is not seen in the laboratory, perhaps due to inappropriate nesting material rather than the nest-building ability of the mice. Here we focus on the use of naturalistic nesting materials to test whether they improve nest quality through the use of a 'naturalistic nest score' system; we also focus on materials that can be sterilized and easily used in existing housing systems. We first determined whether C57BL/6J mice build naturalistic nests when given shredded paper strips. We then compared these shredded paper strips with other commonly used nesting enrichments (facial tissues and compressed cotton squares). Nests were scored for 6 d. We found that the shredded paper strips allowed the mice to build higher quality nests than those built with any of the other materials. Nests built with tissues were of intermediate quality, and nests built with compressed cotton squares were of poor quality, similar to those built by the control group. These results suggest that C57BL/6J mice given appropriate nesting materials can build nests similar to those built by their wild counterparts.

  19. Anxiety and memory deficits induced by tannery effluent in C57BL/6J female mice.

    Science.gov (United States)

    Guimarães, Abraão Tiago Batista; de Oliveira Ferreira, Raissa; de Souza, Joyce Moreira; da Silva, Wellington Alves Mizael; da Silva, Anderson Rodrigo; de LimaRodrigues, Aline Sueli; de Melo E Silva, Daniela; Costa, Renata Mazaro E; da Silva Castro, André Luis; Malafaia, Guilherme

    2016-12-01

    This study aimed to evaluate the behavior of female C57Bl/6J mice exposed to tannery effluents diluted in drinking water. Female mice were divided into a control group, in which the animals received only drinking water, and experimental groups, which received raw tannery effluent in 7.5 and 15 % concentrations diluted in water (period of 60 days). In the last experimental week, the mice (in diestrus phase) were subjected to different behavioral tests: elevated plus-maze, open-field test, forced swim test, and object recognition test. Our data demonstrated that exposure to tannery effluent increased the anxiety index of animals and decreased the locomotion ratio in the central quadrants/total, indicating an increase in anxiety-like behavior. Regarding the forced swim test, we did not observe changes in the evaluated behaviors. There were no statistically significant differences in the recognition index of the novel and familiar object in the groups exposed to tannery effluent compared with the control group, indicating a possible influence of the constituents of tannery effluent on cognition. Thus, our findings support the hypothesis that effluents, containing neurotoxic substances, could cause behavioral disruptions in female C57Bl/6J mice.

  20. /sup 57/Fe impurity atom lattice dynamics and systematics in group V and VI host metals

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, R.D.; Kitchens, T.A. Jr.; Erickson, D.J.

    1976-01-01

    The Moessbauer recoil-free fraction f and thermal shift have been measured for very dilute /sup 57/Fe impurities in body-centered cubic V, Nb, Mo, Ta, and W host metals in the range 4 to 860/sup 0/K. These experimental quantities have been interpreted in terms of an impurity-atom lattice-dynamical model of Mannheim where the important parameter ..gamma../sub ih//..gamma../sub hh/ is a measure of the coupling of the impurity atom to the host lattice relative to the corresponding coupling in the pure host lattice. Values of ..gamma../sub ih//..gamma../sub hh/ for each host from the f-value data were obtained and, independently, from the shift data, and for each host rather good agreement is obtained. The general trend of the data shows that for neighboring hosts of the same row of the periodic table, the relative /sup 57/Fe impurity binding is stronger for the Group V host than for the Group VI host. The results also support a previous conjecture that the nearest-neighbor binding between the impurity and the host should be proportional to a geometric mean of the nearest-neighbor couplings for a lattice consisting entirely of impurity atoms and for a lattice of host atoms only.

  1. FOURNIER’S GANGRENE: REVIEW OF 57 CASES IN TERTIARY INSTITUTION

    Directory of Open Access Journals (Sweden)

    Pradeep

    2015-09-01

    Full Text Available INTRODUCTION : Fournier's gangrene is a rapidly spreading polymicrobial necrotising fascitis affecting the perineum, perianal and genital regions but remarkably sparing the testicle, bladder and rectum due to their separate blood supply which is directly from the aorta. The purpose of this study is to share our experience in the management of Fournier's gangrene. MATERIAL & METHOD S : We had retrospectively analysed the medical records of 57 patients admitted with Fournier's gangrene between January 2012 to January 2015 in Chhattisgarh institute of medical sciences. Data extracted from these includes patient's age, sex, hospital stay, Premorbid diseases, morbidity, mortality, laboratory investigations and treatment carried out. RESULTS: 57 patients were admitted and managed for Fournier's gangrene during the study period. All the patients were male and mean age was 41 years (05 - 76. 6 patients died, mortality was 10.52%. The shortest hospital stay was 5 days and longest was 44 days. Polymicrobial synergistic infection was com mon in most of the cases (77.19%. CONCLUSION : Fournier's gangrene is a life threatening disease and world - wide in its distribution. It is a rapidly progressive, fulminant polymicrobial synergistic infection of the perineum and genitals, now changing its p attern. Extensive debridement and broad spectrum intravenous antibiotics remain mainstay of treatment.

  2. Inhibition of metastatic lung cancer in C57BL/6 mice by marine mangrove Rhizophora apiculata.

    Science.gov (United States)

    Prabhu, V Vinod; Guruvayoorappan, C

    2013-01-01

    Metastasis is one of the hallmarks of malignant neoplasms and is the leading cause of death in many cancer patients. A major challenge in cancer treatment is to find better ways to specifically target tumor metastasis. In this study, the anti-metastatic potential of the methanolic extract of Rhizophora apiculata (R.apiculata) was evaluated using the B16F-10 melanoma induced lung metastasis model in C57BL/6 mice. Metastasis was induced in C57BL/6 mice by injecting highly metastatic B16F-10 melanoma cells through the lateral tail vein. Simultaneous treatment with R.apiculata extract (10 mg/kg b.wt (intraperitoneal) significantly (p<0.01) inhibited pulmonary tumor nodule formation (41.1 %) and also increased the life span (survival rate) 107.3 % of metastatic tumor bearing animals. The administration of R.apiculata extract significantly (p<0.01) reduced biochemical parameters such as lung collagen hydroxyproline, hexosamine, uronic acid content, serum nitric oxide (NO), γ-glutamyl transpeptidase (GGT) and sialic acid levels when compared to metastasis controls. These results correlated with lung histopathology analysis of R.apiculata extract treated mice showing reduction in lung metastasis and tumor masses. Taken together, our findings support that R.apiculata extract could be used as a potential anti-metastasis agent against lung cancer.

  3. Low Energy Electron Diffraction Structural Analysis of Au(111)-(5x5)-7S

    Science.gov (United States)

    Ash, Stephanie; Caragiu, Mellita; McGuirk, Garry; Shin, Heekeun; Diehl, Renee

    2011-10-01

    The clean Au(111) surface is known to undergo several structural changes when exposed to adsorbates, in particular sulfur. As the sulfur coverage increases towards 1ML, the structure of the gold (111) surface has been observed to go through a range of changes as follows: unreconstructed (1x1), followed by a (5x5)-7S structure, then a (3x3)R30^o-S phase, and eventually an incommensurate ``complex'' phase. The current LEED study focuses on the intermediate Au(111)-(5x5)-7S phase. The 7 sulfur atoms in each unit cell are found to occupy fcc hollow sites. There is considerable rumpling of the sulfur adsorbed layer, as well as the top gold layers in the surface, which results in an average S-Au distance of 1.54±0.06å, followed by the next Au-Au average interlayer spacing of 2.37±0.01å. When comparing the latter value to the bulk interlayer spacing of clean gold, of 2.35å, a slight expansion is noticed. The results are compared to the structural information obtained by other studies of the same Au(111)-(5x5) phase.

  4. KEY COMPARISON: Final report on CCQM-K57: Chemical composition of clay

    Science.gov (United States)

    Salas, Antonio; Ramírez, Estele

    2009-01-01

    After the successful completion of the pilot study, CCQM-P65 [1], the Inorganic Analysis Working Group of CCQM agreed to conduct key comparison CCQM-K57, Chemical composition of clay, in Paris, April 2006. The natural mass fraction levels of five elements—Si, Ca, Fe, Al and Mg—were measured and reported as oxides in clay. Six national metrology institutes participated in CCQM K57, and CENAM (Querétaro, Mexico) coordinated. The methods employed were isotope dilution mass spectrometry (IDMS), inductively coupled plasma-mass spectrometry (ICP-MS), inductively coupled plasma-optical emission spectrometry (ICP-OES) using the dehydration method and condensation method, gravimetric analysis, neutron activation analysis (NAA), prompt gamma activation analysis (PGAA) and x-ray fluorescence spectrometry (XRF) with the reconstitution method and external calibration. This final report presents the capability of the participant institutes, based on the KCRV, which was approved at the IAWG spring meeting in 2008, and the equivalence statements regarding the KCRV, approved at its autumn meeting. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).

  5. {sup 57}Fe Mössbauer study of the Chainpur meteorite

    Energy Technology Data Exchange (ETDEWEB)

    Elewa, Nancy N., E-mail: nancy.elewa@student.adfa.edu.au; Cobas, R.; Cadogan, J. M. [The University of New South Wales at the Australian Defence Force Academy, School of Physical, Environmental and Mathematical Sciences (Australia)

    2016-12-15

    The Chainpur meteorite is one of 23 ordinary chondrites classified as LL3-type (low-Fe & low-metal). It was observed as a shower of stones falling on May 9, 1907 in Uttar Pradesh, India. We report here the characterization of the Fe-bearing phases in this chondrite using {sup 57}Fe Mössbauer spectroscopy carried out at 298 K, 120 K, 50 K and 13 K. The paramagnetic doublets of olivine and pyroxene dominate the room temperature spectrum, accounting for around 70 % of the spectral area. Moreover, a doublet present with a spectral area of 5 % and assigned to a superparamagnetic Fe {sup 3+} phase is a consequence of terrestrial weathering. On the basis of the measured {sup 57}Fe electric quadrupole splitting of the olivine component at room temperature we estimate the mean Fe:Mg ratio in this meteoritic olivine to be around 35:65 % although there is clearly a wide range of composition. The effects of magnetic ordering of the major components olivine and pyroxene are observed at 13 K.

  6. Respiratory syncytial virus increases lung cellular bioenergetics in neonatal C57BL/6 mice

    Energy Technology Data Exchange (ETDEWEB)

    Alsuwaidi, Ahmed R., E-mail: alsuwaidia@uaeu.ac.ae [Departments of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain (United Arab Emirates); Albawardi, Alia, E-mail: alia.albawardi@uaeu.ac.ae [Departments of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain (United Arab Emirates); Almarzooqi, Saeeda, E-mail: saeeda.almarzooqi@uaeu.ac.ae [Departments of Pathology, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain (United Arab Emirates); Benedict, Sheela, E-mail: sheela.benedict@uaeu.ac.ae [Departments of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain (United Arab Emirates); Othman, Aws R., E-mail: aws.rashad@uaeu.ac.ae [Departments of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain (United Arab Emirates); Hartwig, Stacey M., E-mail: stacey-hartwig@uiowa.edu [Department of Microbiology, Department of Pathology and Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA 52242 (United States); Varga, Steven M., E-mail: steven-varga@uiowa.edu [Department of Microbiology, Department of Pathology and Interdisciplinary Graduate Program in Immunology, University of Iowa, Iowa City, IA 52242 (United States); Souid, Abdul-Kader, E-mail: asouid@uaeu.ac.ae [Departments of Pediatrics, College of Medicine and Health Sciences, United Arab Emirates University, P.O. Box 17666, Al Ain (United Arab Emirates)

    2014-04-15

    We have previously reported that lung cellular bioenergetics (cellular respiration and ATP) increased in 4–10 week-old BALB/c mice infected with respiratory syncytial virus (RSV). This study examined the kinetics and changes in cellular bioenergetics in ≤2-week-old C57BL/6 mice following RSV infection. Mice (5–14 days old) were inoculated intranasally with RSV and the lungs were examined on days 1–10 post-infection. Histopathology and electron microscopy revealed preserved pneumocyte architectures and organelles. Increased lung cellular bioenergetics was noted from days 1–10 post-infection. Cellular GSH remained unchanged. These results indicate that the increased lung cellular respiration (measured by mitochondrial O{sub 2} consumption) and ATP following RSV infection is independent of either age or genetic background of the host. - Highlights: • RSV infection increases lung cellular respiration and ATP in neonatal C57BL/6 mice. • Increased lung cellular bioenergetics is a biomarker of RSV infection. • Lung cellular glutathione remains unchanged in RSV infection.

  7. Minocycline does not evoke anxiolytic and antidepressant-like effects in C57BL/6 mice.

    Science.gov (United States)

    Vogt, M A; Mallien, A S; Pfeiffer, N; Inta, I; Gass, P; Inta, D

    2016-03-15

    Minocycline is a broad-spectrum tetracycline antibiotic with multiple actions, including anti-inflammatory and neuroprotective effects, that was proposed as novel treatment for several psychiatric disorders including schizophrenia and depression. However, there are contradictory results regarding antidepressant effects of minocycline in rodent models. Additionally, the possible anxiolytic effect of minocycline is still poorly investigated. Therefore, we aimed to clarify in the present study the influence of minocycline on behavioral correlates of mood disorders in standard tests for depression and anxiety, the Porsolt Forced Swim Test (FST), Elevated O-Maze, Dark-Light Box Test and Openfield Test in adult C57BL/6 mice. We found, unexpectedly, that mice treated with minocycline (20-40mg/kg, i.p.) did not display antidepressant- or anxiolytic-like behavioral changes in contrast to mice treated with diazepam (0.5mg/kg, anxiety tests) or imipramine (20mg/kg, depressive-like behavior). These results are relevant for future studies, considering that C57BL/6 mice, the most widely used strain in pharmacological and genetic animal models, did not react as expected to the treatment regime applied. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Lack of evidence for neonatal misoprostol neurodevelopmental toxicity in C57BL6/J mice.

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    Claire M Koenig

    Full Text Available Misoprostol is a synthetic analogue of prostaglandin E1 that is administered to women at high doses to induce uterine contractions for early pregnancy termination and at low doses to aid in cervical priming during labor. Because of the known teratogenic effects of misoprostol when given during gestation and its effects on axonal growth in vitro, we examined misoprostol for its potential as a neurodevelopmental toxicant when administered to neonatal C57BL6/J mice. Mice were injected subcutaneously (s.c. with 0.4, 4 or 40 µg/kg misoprostol on postnatal day 7, the approximate developmental stage in mice of human birth, after which neonatal somatic growth, and sensory and motor system development were assessed. These doses were selected to span the range of human exposure used to induce labor. In addition, adult mice underwent a battery of behavioral tests relevant to neurodevelopmental disorders such as autism including tests for anxiety, stereotyped behaviors, social communication and interactions, and learning and memory. No significant effects of exposure were found for any measure of development or behavioral endpoints. In conclusion, the results of the present study in C57BL/6J mice do not provide support for neurodevelopmental toxicity after misoprostol administration approximating human doses and timed to coincide with the developmental stage of human birth.

  9. Effects of risperidone on energy balance in female C57BL/6J mice.

    Science.gov (United States)

    Li, Xingsheng; Johnson, Maria S; Smith, Daniel L; Li, Yan; Kesterson, Robert A; Allison, David B; Nagy, Tim R

    2013-09-01

    To investigate the effect of risperidone on energy expenditure and weight gain in female C57BL/6J mice. Body weight and composition, food intake, energy expenditure, and activity were determined weekly. mRNA expression of uncoupling protein 1 in brown adipose tissue, orexin, and brain-derived neurotrophic factor in the hypothalamus were quantified using real-time PCR. Risperidone tended to induce a greater body weight gain (P = 0.052) and significantly higher food intake (P = 0.038) relative to the placebo-treated group. Risperidone-treated mice had a higher resting energy expenditure (P = 0.001) and total energy expenditure (TEE) (P = 0.005) than the placebo group. There were no effects of treatment, time, and treatment by time on non-resting (or activity-related) energy expenditure between groups. Risperidone-treated mice showed a significantly lesser locomotor activity than placebo-treated mice over 3 weeks (P energy expenditure were accompanied by higher levels of UCP1 mRNA in BAT. The increased TEE could not offset the total intake of energy through risperidone-induced hyperphagia, therefore resulting in weight gain in female C57BL/6J mice. Copyright © 2013 The Obesity Society.

  10. Synthesis and Fluorescence Properties of 5,7-Diphenylquinoline and 2,5,7-Triphenylquinoline Derived from m-Terphenylamine

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    Hong Wang

    2007-05-01

    Full Text Available Synthesis of 5,7-phenylquinoline from the Skraup reaction of m-terphenyl-amine and glycerol in the presence of acid is reported. Further reaction of 5,7-diphenyl-quinoline with phenyl lithium prepared in situ led to the formation of 2,5,7-triphenyl-quinoline. All of the products and their intermediates were characterized and the UV-Vis and photo-luminescence (PL spectra of m-terphenylamine, 5,7-diphenylquinoline and 2,5,7-triphenylquinoline are also reported.

  11. Infecções dos espaços cervicais: estudo prospectivo de 57 casos

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    Sennes Luiz Ubirajara

    2002-01-01

    Full Text Available Objetivo: apesar da antibioticoterapia, as infecções dos espaços cervicais profundos continuam a ter grande importância, tanto por sua alta incidência, como pelo risco de complicações. Forma de estudo: clínico, prospectivo. Material e método: descrevem-se neste estudo 57 casos de pacientes com diagnóstico de infecção cervical (celulite, abscesso e fasceíte necrotizante internados na Enfermaria de Otorrinolaringologia do Hospital das Clínicas da Faculdade de Medicina da USP entre janeiro de 1999 e janeiro de 2001. Cinqüenta pacientes (87,7% apresentavam abscesso cervical, cinco (8,8%, celulite e dois pacientes (3,5%, fasceíte necrotizante. A infecção odontogênica foi o foco de origem mais prevalente, responsável por 24 casos (42%, seguida das amigdalites (17,5% e linfadenites (15,8%. Os espaços cervicais mais acometidos foram o submandibular (57,9%, o sublingual (26,3% e o parafaríngeo (24,6%. Em 53 pacientes realizaram-se culturas das quais 71,7% foram positivas, sendo que 20,8% destas apresentaram flora mista. Os microorganismos mais prevalentes dentre os aeróbicos foi o Streptococcus viridans (41,5% e, dentre os anaeróbios, Peptostreptococcus micros e Peptostreptococcus sp (5,7% e 3,8%, respectivamente. A associação entre penicilina cristalina e metronidazol foi o tratamento preconizado em 31 pacientes (54,3%. Nos demais, diversos antibióticos como clindamicina, cefalosporinas de terceira geração, cloranfenicol e oxacilina foram utilizados. Cinqüenta e quatro pacientes (94,7% evoluíram satisfatoriamente, dois (3,5% apresentaram deiscência da ferida cirúrgica e um (1,7% foi a óbito por mediastinite. Conclusão: os abscessos cervicais ainda configuram uma importante causa de morbidade em nossa população e suas complicações requerem vigilância para a prevenção e abordagem oportunas, especialmente pelo tratamento mais adequado.

  12. The 57Fe Synchrotron Mössbauer Source at the ESRF.

    Science.gov (United States)

    Potapkin, Vasily; Chumakov, Aleksandr I; Smirnov, Gennadii V; Celse, Jean Philippe; Rüffer, Rudolf; McCammon, Catherine; Dubrovinsky, Leonid

    2012-07-01

    The design of a (57)Fe Synchrotron Mössbauer Source (SMS) for energy-domain Mössbauer spectroscopy using synchrotron radiation at the Nuclear Resonance beamline (ID18) at the European Synchrotron Radiation Facility is described. The SMS is based on a nuclear resonant monochromator employing pure nuclear reflections of an iron borate ((57)FeBO(3)) crystal. The source provides (57)Fe resonant radiation at 14.4 keV within a bandwidth of 15 neV which is tunable in energy over a range of about ±0.6 µeV. In contrast to radioactive sources, the beam of γ-radiation emitted by the SMS is almost fully resonant and fully polarized, has high brilliance and can be focused to a 10 µm × 5 µm spot size. Applications include, among others, the study of very small samples under extreme conditions, for example at ultrahigh pressure or combined high pressure and high temperature, and thin films under ultrahigh vacuum. The small cross section of the beam and its high intensity allow for rapid collection of Mössbauer data. For example, the measuring time of a spectrum for a sample in a diamond anvil cell at ∼100 GPa is around 10 min, whereas such an experiment with a radioactive point source would take more than one week and the data quality would be considerably less. The SMS is optimized for highest intensity and best energy resolution, which is achieved by collimation of the incident synchrotron radiation beam and thus illumination of the high-quality iron borate crystal within a narrow angular range around an optimal position of the rocking curve. The SMS is permanently located in an optics hutch and is operational immediately after moving it into the incident beam. The SMS is an in-line monochromator, i.e. the beam emitted by the SMS is directed almost exactly along the incident synchrotron radiation beam. Thus, the SMS can be easily utilized with all existing sample environments in the experimental hutches of the beamline. Owing to a very strong

  13. Chinese specific characteristics of sporadic Creutzfeldt-Jakob disease: a retrospective analysis of 57 cases.

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    Wei Zhao

    Full Text Available OBJECTIVE: Sporadic Creutzfeldt-Jakob disease (sCJD is a fatal and transmissible neurodegenerative disorder. However, no studies have reported Chinese specific characteristics of sCJD. We aimed to identify differences in sCJD between Chinese patients and patients from other countries. METHODS: The data from 57 Chinese sCJD patients were retrospectively analyzed, including demographic data, clinical manifestations, laboratory examinations, electroencephalograms (EEGs, diffusion-weighted imaging (DWI scans, positron emission tomography (PET scans, and pathological results. RESULT: The disease was pathologically confirmed in 11 patients. 39 cases were diagnosed as probable sCJD, and 7 were possible. Of the total cases, 33 were male, and 24 were female. The onset age ranged from 36 to 75 years (mean: 55.5, median: 57. Disease onset before the age of 60 occurred in 57.9% of patients. The disease duration from onset to death ranged 5-22 months (mean: 11.6, median: 11, and 51.9% of patients died 7 to 12 months after disease onset. The majority of patients presented with sub-acute onset with progressive dementia. 3 of the 9 patients who took 14-3-3 protein analysis had positive results (33.3%. The sensitivity of EEG was 79.6% (43/54. For DWI and PET examinations, the sensitivities were 94% (47/50 and 94.1% (16/17, respectively. In seven patients who did not show typical hyper-intensities on the first DWI examination, abnormalities of hypo-metabolism in the cerebral cortex were clearly detected by PET. In 13 out of the 17 patients, PET detected extra abnormal regions in addition to the hyper-intense areas observed in DWI. CONCLUSION: This is the first study to indicate that Chinese sCJD patients have a much earlier onset age and a longer disease duration than other populations, which is most likely related to racial differences. The longer disease duration may also be a probable characteristic of Asian populations. PET had high sensitivity for the

  14. Traumatismo da medula espinhal em cães e gatos: estudo prospectivo de 57 casos Spinal cord injuries in dogs and cats: prospective study of 57 cases

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    Daniela S. Mendes

    2012-12-01

    Full Text Available O traumatismo da medula espinhal é uma causa comum de disfunção neurológica em cães e gatos. Lesões nestas espécies ocorrem devido a vários tipos de acidentes, podendo ocasionar sequelas que prejudicam o paciente como animais de estimação ou lesões que comprometam a vida. O objetivo principal deste estudo foi a monitoração intensiva de animais com lesão medular atendidos entre 8/2009 e 11/2010 no Hospital Veterinário da Universidade Estadual de Londrina, estudando os fatores epidemiológicos e etiológicos, fatores de risco, segmentos medulares mais afetados, resultados dos tratamentos conservativo ou cirúrgico, relação entre o tempo de atendimento e a recuperação do animal, eficácia e efeitos colaterais do succinato sódico de metilprednisolona, complicações, sequelas e evolução do quadro. Durante este período foram acompanhados 57 animais (48 cães e nove gatos. Observou-se predominância de animais machos (68% e domiciliados (79%. A principal causa de lesão foi o atropelamento (66%. O tempo entre o trauma e o atendimento foi menos de oito horas em 42% dos casos e mais de um dia em 51%. O segmento medular mais atingido foi o toracolombar (52%. Vinte animais foram submetidos à eutanásia após o atendimento inicial devido ao prognóstico reservado. O tratamento conservativo com repouso e/ou imobilização externa foi realizado em 29 animais e um bom resultado com esta modalidade foi obtida em 72,4% dos casos: houve recuperação funcional total em 17 (58,6% animais e parcial em quatro (13,8%. Quatro animais não se recuperaram e quatro animais morreram. Oito pacientes foram submetidos ao tratamento cirúrgico, sendo que três animais recuperaram-se, um paciente não apresentou recuperação e quatro morreram ou foram submetidos a eutanásia devido a complicações no trans ou pós-operatório. O tratamento conservativo foi viável, principalmente em cães com lesão medular cervical.Spinal cord injury is a common

  15. Ferritin accumulation and uroporphyrin crystal formation in hepatocytes of C57BL/10 mice: A time-course study

    NARCIS (Netherlands)

    P.D. Siersema (Peter); M.I. Cleton-Soeteman (Maud); W.C. de Bruijn (Wim); F.J.W. ten Kate (Fiebo); H.G. van Eijk (Henk); J.H.P. Wilson (Paul)

    1993-01-01

    textabstractTo establish the time-sequence relationship between ferritin accumulation and uroporphyrin crystal formation in livers of C57BL/10 mice, a biochemical, morphological and morphometrical study was performed. Uroporphyria was induced by the intraperitoneal administration of

  16. 2018-01-12T03:57:07Z https://www.ajol.info/index.php/index/oai oai ...

    African Journals Online (AJOL)

    article/48247 2018-01-12T03:57:07Z indilinga:ART Indigenous Knowledge Management Transfer Systems Across Generations In Zimbabwe Mpofu, D Miruka, C Indigenous Knowledge Systems; Knowledge Management; Knowledge Transfer.

  17. Reply to C. Stewart’s Letter to the Editor Re: Teoh SL et al., Nutrients 2016, 8, 57

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    Siew Li Teoh

    2016-04-01

    Full Text Available In a recent systematic review and meta-analysis report (Nutrients 2016, 8, 57, we critically appraised and summarized current evidence to determine the effects of chicken essence in improving cognitive functions as well as its safety. [...

  18. Anti-Leukemic Activity of Shikonin: Role of ERP57 in Shikonin Induced Apoptosis in Acute Myeloid Leukemia

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    Rachana Trivedi

    2016-07-01

    Full Text Available Background/Aims: ER-Stress and activation of unfolded protein response belong to the major factors involved in chemoresistance in cancer cells. In this study we investigated the effect of shikonin on the survival of acute myeloid leukemia cells and the role of ER-stress protein ERP57, a protein disulfide isomerase, in improvement of chemotherapy. Methods: Using MTT assay we studied cytotoxic effects of shikonin on HL-60 cells. The flow cytometry was adopted to examine the shikonin induced mode of cell death in HL-60 cells. The overall protein expression alteration resulting from shikonin treatment was investigated using proteomics methods. Western blotting was performed to quantify the alteration in protein expression in HL-60 after shikonin treatment. Silencing and overexpression studies were carried out to highlight the therapeutic role of ERP57 in shikonin effect on AML cells. Results: Shikonin induces apoptosis in HL-60 cells without significant effect on Primary cells from healthy volunteers. The apoptotic effect was dose and time dependent and was accompanied by strong alteration in cell proteome. Among the proteins targeted by shikonin, ERP57 was significantly downregulated in HL-60 after treatment. Compared to healthy control ERP57 was found to be highly expressed in AML cell line HL60 and was downregulated after shikonin treatment. Overexpression of ERP57 protected HL-60 from shikonin induced apoptosis, whereas knockdown of ERP57 expression resulted in increase in shikonin induced apoptosis. Conclusions: Our results demonstrate that ERP57 plays a crucial role in resistance towards shikonin induced apoptosis in AML cells. Targeting of ERP57 might offer a new therapeutic option for the treatment of acute myeloid leukemia.

  19. Competitive and cooperative interactions mediate RNA transfer from herpesvirus saimiri ORF57 to the mammalian export adaptor ALYREF.

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    Richard B Tunnicliffe

    2014-02-01

    Full Text Available The essential herpesvirus adaptor protein HVS ORF57, which has homologs in all other herpesviruses, promotes viral mRNA export by utilizing the cellular mRNA export machinery. ORF57 protein specifically recognizes viral mRNA transcripts, and binds to proteins of the cellular transcription-export (TREX complex, in particular ALYREF. This interaction introduces viral mRNA to the NXF1 pathway, subsequently directing it to the nuclear pore for export to the cytoplasm. Here we have used a range of techniques to reveal the sites for direct contact between RNA and ORF57 in the absence and presence of ALYREF. A binding site within ORF57 was characterized which recognizes specific viral mRNA motifs. When ALYREF is present, part of this ORF57 RNA binding site, composed of an α-helix, binds preferentially to ALYREF. This competitively displaces viral RNA from the α-helix, but contact with RNA is still maintained by a flanking region. At the same time, the flexible N-terminal domain of ALYREF comes into contact with the viral RNA, which becomes engaged in an extensive network of synergistic interactions with both ALYREF and ORF57. Transfer of RNA to ALYREF in the ternary complex, and involvement of individual ORF57 residues in RNA recognition, were confirmed by UV cross-linking and mutagenesis. The atomic-resolution structure of the ORF57-ALYREF interface was determined, which noticeably differed from the homologous ICP27-ALYREF structure. Together, the data provides the first site-specific description of how viral mRNA is locked by a herpes viral adaptor protein in complex with cellular ALYREF, giving herpesvirus access to the cellular mRNA export machinery. The NMR strategy used may be more generally applicable to the study of fuzzy protein-protein-RNA complexes which involve flexible polypeptide regions.

  20. p57KIP2 expression and loss of heterozygosity during immortal conversion of cultured human mammary epithelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Nijjar, Tarlochan; Wigington, Don; Garbe, James C.; Waha, Andreas; Stampfer, Martha R.; Yaswen, Paul

    1999-08-01

    The authors have uncovered a novel role for the cyclin-dependent kinase inhibitor, p57KIP2, during the immortalization of cultured human mammary epithelial cells (HMEC). HMEC immortalized following chemical carcinogen exposure initially expressed little or no telomerase activity, and their telomeres continued to shorten with passage. Cell populations whose mean terminal restriction fragment (TRF) length declined and exhibited slow heterogeneous growth, and contained many non-proliferative cells. These conditionally immortal HMEC cultures accumulated large quantities of p57 protein. With continued passage, the conditionally immortal cell populations very graduall2048nverted to a fully immortal phenotype of good uniform growth, expression of high levels of telomerase activity, and stabilization of telomere length. The fully immortal good growing HMEC did not accumulate p57 in G0 or during the cell cycle. DNA and RNA analysis of mass populations and individual subclones of conditionally immortal HMEC line 184A1 showed that continued growth of conditionally immortal cells with critically short telomeres was repeatedly accompanied by loss of the expressed p57 allele, and transient expression of the previously imprinted allele. Conditionally immortal 184A1 with mean TRF > 3 kb infected with retroviruses containing the p57 gene exhibited premature slow heterogeneous growth. Conversely, exogenous expression of hTERT, the catalytic subunit of telomerase, in 184A1 with mean TRF > 3 kb prevented both the slow heterogeneous growth phase and accumulation of p57 in cycling populations. These data indicate that in HMEC which have overcome replicative senescence, p57 may provide an additional barrier against indefinite proliferation. Overcoming p57 mediated growth inhibition in these cells may be crucial for acquisition of the unlimited growth potential thought to be critical for malignant progression.