FY2017 Updates to the SAS4A/SASSYS-1 Safety Analysis Code

Energy Technology Data Exchange (ETDEWEB)

Fanning, T. H. [Argonne National Lab. (ANL), Argonne, IL (United States)

2017-09-30

The SAS4A/SASSYS-1 safety analysis software is used to perform deterministic analysis of anticipated events as well as design-basis and beyond-design-basis accidents for advanced fast reactors. It plays a central role in the analysis of U.S. DOE conceptual designs, proposed test and demonstration reactors, and in domestic and international collaborations. This report summarizes the code development activities that have taken place during FY2017. Extensions to the void and cladding reactivity feedback models have been implemented, and Control System capabilities have been improved through a new virtual data acquisition system for plant state variables and an additional Block Signal for a variable lag compensator to represent reactivity feedback for novel shutdown devices. Current code development and maintenance needs are also summarized in three key areas: software quality assurance, modeling improvements, and maintenance of related tools. With ongoing support, SAS4A/SASSYS-1 can continue to fulfill its growing role in fast reactor safety analysis and help solidify DOE’s leadership role in fast reactor safety both domestically and in international collaborations.

Implementation, verification, and validation of the FPIN2 metal fuel pin mechanics model in the SASSYS/SAS4A LMR transient analysis codes

International Nuclear Information System (INIS)

Sofu, T.; Kramer, J.M.

1994-01-01

The metal fuel version of the FPIN2 code which provides a validated pin mechanics model is coupled with SASSYS/SAS4A Version 3.0 for single pin calculations. In this implementation, SASSY/SAS4A provides pin temperatures, and FPIN2 performs analysis of pin deformation and predicts the time and location of cladding failure. FPIN2 results are also used for the estimates of axial expansion of fuel and associated reactivity effects. The revalidation of the integrated SAS-FPIN2 code system is performed using TREAT tests

Analysis of metal fuel transient overpower experiments with the SAS4A accident analysis code

International Nuclear Information System (INIS)

Tentner, A.M.; Kalimullah; Miles, K.J.

1990-01-01

The results of the SAS4A analysis of the M7 TREAT Metal fuel experiment are presented. New models incorporated in the metal fuel version of SAS4A are described. The computational results are compared with the experimental observations and this comparison is used in the interpretation of physical phenomena. This analysis was performed using the integrated metal fuel SAS4A version and covers a wide range of events, providing an increased degree of confidence in the SAS4A metal fuel accident analysis capabilities

Coupling the System Analysis Module with SAS4A/SASSYS-1

Energy Technology Data Exchange (ETDEWEB)

Fanning, T. H. [Argonne National Lab. (ANL), Argonne, IL (United States); Hu, R. [Argonne National Lab. (ANL), Argonne, IL (United States)

2016-09-30

SAS4A/SASSYS-1 is a simulation tool used to perform deterministic analysis of anticipated events as well as design basis and beyond design basis accidents for advanced reactors, with an emphasis on sodium fast reactors. SAS4A/SASSYS-1 has been under development and in active use for nearly forty-five years, and is currently maintained by the U.S. Department of Energy under the Office of Advanced Reactor Technology. Although SAS4A/SASSYS-1 contains a very capable primary and intermediate system modeling component, PRIMAR-4, it also has some shortcomings: outdated data management and code structure makes extension of the PRIMAR-4 module somewhat difficult. The user input format for PRIMAR-4 also limits the number of volumes and segments that can be used to describe a given system. The System Analysis Module (SAM) is a fairly new code development effort being carried out under the U.S. DOE Nuclear Energy Advanced Modeling and Simulation (NEAMS) program. SAM is being developed with advanced physical models, numerical methods, and software engineering practices; however, it is currently somewhat limited in the system components and phenomena that can be represented. For example, component models for electromagnetic pumps and multi-layer stratified volumes have not yet been developed. Nor is there support for a balance of plant model. Similarly, system-level phenomena such as control-rod driveline expansion and vessel elongation are not represented. This report documents fiscal year 2016 work that was carried out to couple the transient safety analysis capabilities of SAS4A/SASSYS-1 with the system modeling capabilities of SAM under the joint support of the ART and NEAMS programs. The coupling effort was successful and is demonstrated by evaluating an unprotected loss of flow transient for the Advanced Burner Test Reactor (ABTR) design. There are differences between the stand-alone SAS4A/SASSYS-1 simulations and the coupled SAS/SAM simulations, but these are mainly

Sas2

International Development Research Centre (IDRC) Digital Library (Canada)

The fascinating multi-country examples in the Guide illustrate how SAS2 ... The challenge is to raise all forms of inquiry to the power of two: making the .... This requires an ability to suspend judgment, consider the views of others, ..... Our view is that the drive to think "holistically" must always be expressed with local color and ...

A new package: MySAS for small angle scattering data analysis

International Nuclear Information System (INIS)

Huang Chaoqiang; Xia Qingzhong; Yan Guanyun; Sun Guang'ai; Chen Bo

2010-01-01

In this paper, A MySAS package, which is verified on Windows XP, can easily convert two-dimensional data in small angle neutron and X-ray scattering analysis, operate individually and execute one particular operation as numerical data reduction or analysis, and graphical visualization. This MySAS package can implement the input and output routines via scanning certain properties, thus recalling completely sets of repetition input and selecting the input files. On starting from the two-dimensional files, the MySAS package can correct the anisotropic or isotropic data for physical interpretation and select the relevant pixels. Over 50 model functions are fitted by the POWELL code using χ 2 as the figure of merit function. (authors)

Vybrané výběrové statistické metody v programu SAS

OpenAIRE

Voříšek, Jan

2009-01-01

In the present work we study methodology of different kinds of sample surveys and their design in SAS software. Creating of SAS Enterprise Guide Add-In was the fundamental creative part of this work. This Add-In enables to compute important statistics of sample surveys, without need of being familiar with SAS code. Add-In was created in MSFT Visual Studio 2003 in C # language using a tamplate for Add-Ins provided by SAS. This work contains a general description of the creation of an Add-In as...

SAS Code for Calculating Intraclass Correlation Coefficients and Effect Size Benchmarks for Site-Randomized Education Experiments

Science.gov (United States)

Brandon, Paul R.; Harrison, George M.; Lawton, Brian E.

2013-01-01

When evaluators plan site-randomized experiments, they must conduct the appropriate statistical power analyses. These analyses are most likely to be valid when they are based on data from the jurisdictions in which the studies are to be conducted. In this method note, we provide software code, in the form of a SAS macro, for producing statistical…

Implementation of Surface Detector Option in SCALE SAS4 Shielding Module

International Nuclear Information System (INIS)

Broadhead, B.L.; Emmett, M.B.; Tang, J.S.

1999-01-01

The Shielding Analysis Sequence No. 4 (SAS4) in the Standardized Cask Analysis and Licensing Evaluation System (SCALE) is designed to aid the novice user in the preparation of detailed three-dimensional models and radiation protection studies of transportation or storage packages containing spent fuel from a nuclear reactor facility. The underlying methodology in these analyses is the Monte Carlo particle-tracking approach as incorporated into the MORSE-SGC computer code. The use of these basic procedures is enhanced via the automatic generation of the biasing parameters in the SAS4 sequence, which dramatically increases the calculational efficiency of most standard shielding problems. Until recently the primary mechanism for dose estimates in SAS4 was the use of point detectors, which were effective for single-dose locations, but inefficient for quantification of dose-rate profiles. This paper describes the implementation of a new surface detector option for SAS4 with automatic discretization of the detector surface into multiple segments or subdetectors. Results from several sample problems are given and discussed

Homework Solutions S.A.S.

OpenAIRE

Acero Mora, Mariluz; Hernández Laguna, Liliana

2012-01-01

Homework Solutions S.A.S, será una empresa de servicios dedicada a brindar asesorías de tareas y trabajos bilingües con soluciones al instante sin que los padres de familia tengan que pagar por meses o semestres. Está previsto que dicha empresa empiece operaciones en el mes de Enero de 2013. Homework Solutions S.A.S, trabajará a domicilio, en los colegios que requieran sus servicios y en su sede principal ubicada al norte de la ciudad de Bogotá.

Coupled MCNP - SAS-SFR calculations for sodium fast reactor core at steady-state - 15460

International Nuclear Information System (INIS)

Ponomarev, A.; Travleev, A.; Pfrang, W.; Sanchez, V.

2015-01-01

The prediction of core parameters at steady state is the first step when studying core accident transient behaviour. At this step thermal hydraulics (TH) and core geometry parameters are calculated corresponding to initial operating conditions. In this study we present the coupling of the SAS-SFR code to the Monte-Carlo neutron transport code MCNP at steady state together with application to the European Sodium Fast Reactor (ESFR). The SAS-SFR code employs a multi-channel core representation where each channel represents subassemblies with similar power, thermal-hydraulics and pin mechanics conditions. For every axial node of every channel the individual geometry and material compositions parameters are calculated in accord with power and cooling conditions. This requires supplying the SAS-SFR-code with nodal power values which should be calculated by neutron physics code with given realistic core parameters. In the conventional approach the neutron physics model employs some core averaged TH and geometry data (fuel temperature, coolant density, core axial and radial expansion). In this study we organize a new approach coupling the MCNP neutron physics models and the SAS-SFR models, so that calculations of power can be improved by using distributed core parameters (TH and geometry) taken from SAS-SFR. The MCNP code is capable to describe cores with distributed TH parameters and even to model non-uniform axial expansion of fuel subassemblies. In this way, core TH and geometrical data calculated by SAS-SFR are taken into account accurately in the neutronics model. The coupling implementation is done by data exchange between two codes with help of processing routines managed by driver routine. Currently it is model-specific and realized for the ESFR 'Reference Oxide' core. The Beginning-Of-Life core state is considered with 10 channel representation for fuel subassemblies. For this model several sets of coupled calculations are performed, in which different

A SAS2H/KENO-V Methodology for 3D Full Core depletion analysis

International Nuclear Information System (INIS)

Milosevic, M.; Greenspan, E.; Vujic, J.; Petrovic, B.

2003-04-01

This paper describes the use of a SAS2H/KENO-V methodology for 3D full core depletion analysis and illustrates its capabilities by applying it to burnup analysis of the IRIS core benchmarks. This new SAS2H/KENO-V sequence combines a 3D Monte Carlo full core calculation of node power distribution and a 1D Wigner-Seitz equivalent cell transport method for independent depletion calculation of each of the nodes. This approach reduces by more than an order of magnitude the time required for getting comparable results using the MOCUP code system. The SAS2H/KENO-V results for the asymmetric IRIS core benchmark are in good agreement with the results of the ALPHA/PHOENIX/ANC code system. (author)

Particle and particle systems characterization small-angle scattering (SAS) applications

CERN Document Server

Gille, Wilfried

2016-01-01

Small-angle scattering (SAS) is the premier technique for the characterization of disordered nanoscale particle ensembles. SAS is produced by the particle as a whole and does not depend in any way on the internal crystal structure of the particle. Since the first applications of X-ray scattering in the 1930s, SAS has developed into a standard method in the field of materials science. SAS is a non-destructive method and can be directly applied for solid and liquid samples. Particle and Particle Systems Characterization: Small-Angle Scattering (SAS) Applications is geared to any scientist who might want to apply SAS to study tightly packed particle ensembles using elements of stochastic geometry. After completing the book, the reader should be able to demonstrate detailed knowledge of the application of SAS for the characterization of physical and chemical materials.

A SAS IML Macro for Loglinear Smoothing

Science.gov (United States)

Moses, Tim; von Davier, Alina

2011-01-01

Polynomial loglinear models for one-, two-, and higher-way contingency tables have important applications to measurement and assessment. They are essentially regarded as a smoothing technique, which is commonly referred to as loglinear smoothing. A SAS IML (SAS Institute, 2002a) macro was created to implement loglinear smoothing according to…

Regression modeling methods, theory, and computation with SAS

CERN Document Server

Panik, Michael

2009-01-01

Regression Modeling: Methods, Theory, and Computation with SAS provides an introduction to a diverse assortment of regression techniques using SAS to solve a wide variety of regression problems. The author fully documents the SAS programs and thoroughly explains the output produced by the programs.The text presents the popular ordinary least squares (OLS) approach before introducing many alternative regression methods. It covers nonparametric regression, logistic regression (including Poisson regression), Bayesian regression, robust regression, fuzzy regression, random coefficients regression,

CTTITEM: SAS macro and SPSS syntax for classical item analysis.

Science.gov (United States)

Lei, Pui-Wa; Wu, Qiong

2007-08-01

This article describes the functions of a SAS macro and an SPSS syntax that produce common statistics for conventional item analysis including Cronbach's alpha, item difficulty index (p-value or item mean), and item discrimination indices (D-index, point biserial and biserial correlations for dichotomous items and item-total correlation for polytomous items). These programs represent an improvement over the existing SAS and SPSS item analysis routines in terms of completeness and user-friendliness. To promote routine evaluations of item qualities in instrument development of any scale, the programs are available at no charge for interested users. The program codes along with a brief user's manual that contains instructions and examples are downloadable from suen.ed.psu.edu/-pwlei/plei.htm.

Validity of Simpson-Angus Scale (SAS) in a naturalistic schizophrenia population.

Science.gov (United States)

Janno, Sven; Holi, Matti M; Tuisku, Katinka; Wahlbeck, Kristian

2005-03-17

Simpson-Angus Scale (SAS) is an established instrument for neuroleptic-induced parkinsonism (NIP), but its statistical properties have been studied insufficiently. Some shortcomings concerning its content have been suggested as well. According to a recent report, the widely used SAS mean score cut-off value 0.3 of for NIP detection may be too low. Our aim was to evaluate SAS against DSM-IV diagnostic criteria for NIP and objective motor assessment (actometry). Ninety-nine chronic institutionalised schizophrenia patients were evaluated during the same interview by standardised actometric recording and SAS. The diagnosis of NIP was based on DSM-IV criteria. Internal consistency measured by Cronbach's alpha, convergence to actometry and the capacity for NIP case detection were assessed. Cronbach's alpha for the scale was 0.79. SAS discriminated between DSM-IV NIP and non-NIP patients. The actometric findings did not correlate with SAS. ROC-analysis yielded a good case detection power for SAS mean score. The optimal threshold value of SAS mean score was between 0.65 and 0.95, i.e. clearly higher than previously suggested threshold value. We conclude that SAS seems a reliable and valid instrument. The previously commonly used cut-off mean score of 0.3 has been too low resulting in low specificity, and we suggest a new cut-off value of 0.65, whereby specificity could be doubled without loosing sensitivity.

Validity of Simpson-Angus Scale (SAS in a naturalistic schizophrenia population

Directory of Open Access Journals (Sweden)

Tuisku Katinka

2005-03-01

Full Text Available Abstract Background Simpson-Angus Scale (SAS is an established instrument for neuroleptic-induced parkinsonism (NIP, but its statistical properties have been studied insufficiently. Some shortcomings concerning its content have been suggested as well. According to a recent report, the widely used SAS mean score cut-off value 0.3 of for NIP detection may be too low. Our aim was to evaluate SAS against DSM-IV diagnostic criteria for NIP and objective motor assessment (actometry. Methods Ninety-nine chronic institutionalised schizophrenia patients were evaluated during the same interview by standardised actometric recording and SAS. The diagnosis of NIP was based on DSM-IV criteria. Internal consistency measured by Cronbach's α, convergence to actometry and the capacity for NIP case detection were assessed. Results Cronbach's α for the scale was 0.79. SAS discriminated between DSM-IV NIP and non-NIP patients. The actometric findings did not correlate with SAS. ROC-analysis yielded a good case detection power for SAS mean score. The optimal threshold value of SAS mean score was between 0.65 and 0.95, i.e. clearly higher than previously suggested threshold value. Conclusion We conclude that SAS seems a reliable and valid instrument. The previously commonly used cut-off mean score of 0.3 has been too low resulting in low specificity, and we suggest a new cut-off value of 0.65, whereby specificity could be doubled without loosing sensitivity.

[Standardization of the Greek version of Zung's Self-rating Anxiety Scale (SAS)].

Science.gov (United States)

Samakouri, M; Bouhos, G; Kadoglou, M; Giantzelidou, A; Tsolaki, K; Livaditis, M

2012-01-01

Self-rating Anxiety Scale (SAS), introduced by Zung, has been widely used in research and in clinical practice for the detection of anxiety. The present study aims at standardizing the Greek version of SAS. SAS consists of 20 items rated on a 1-4 likert type scale. The total SAS score may vary from 20 (no anxiety at all) to 80 (severe anxiety). Two hundred and fifty four participants (114 male and 140 female), psychiatric patients, physically ill and general population individuals, aged 45.40±11.35 years, completed the following: (a) a demographic characteristics' questionnaire, (b) the SAS Greek version, (c) the Spielberg's Modified Greek State-Trait Anxiety Scale (STAI-Gr.-X) and (d) the Zung Depression Rating Scale (ZDRS). Seventy six participants answered the SAS twice within a 12th-day median period of time. The following parameters were calculated: (a) internal consistency of the SAS in terms of Cronbach's α co-efficient, (b) its test-retest reliability in terms of the Intraclass Correlation Coefficient (ICC) and (c) its concurrent and convergent validities through its score's Spearman's rho correlations with both the state and trait subscales of STAI-Gr X and the ZDRS. In addition, in order to evaluate SAS' discriminant validity, the scale's scores of the three groups of participants (psychiatric patients, physically ill and general population individuals) were compared among each other, in terms of Kruskall Wallis and Mann Whitney U tests. SAS Cronbach's alpha equals 0.897 while ICC regarding its test-retest reliability equals 0.913. Spearman's rho concerning validity: (a) when SAS is compared to STAI-Gr.-X (state), equals it 0.767, (b) when SAS is compared to STAI-Gr. X (trait), it equals 0.802 and (c) when SAS is compared to ZDRS, it equals 0.835. The mentally ill scored significantly higher in SAS compared to both the healthy and the general population. In conclusion, the SAS Greek version presents very satisfactory psychometric properties regarding

SAS and R data management, statistical analysis, and graphics

CERN Document Server

Kleinman, Ken

2009-01-01

An All-in-One Resource for Using SAS and R to Carry out Common TasksProvides a path between languages that is easier than reading complete documentationSAS and R: Data Management, Statistical Analysis, and Graphics presents an easy way to learn how to perform an analytical task in both SAS and R, without having to navigate through the extensive, idiosyncratic, and sometimes unwieldy software documentation. The book covers many common tasks, such as data management, descriptive summaries, inferential procedures, regression analysis, and the creation of graphics, along with more complex applicat

Mirror suspension system for the TAMA SAS

CERN Document Server

Takamori, A; Bertolini, A; Cella, G; DeSalvo, R; Fukushima, M; Iida, Y; Jacquier, F; Kawamura, S; Marka, S; Nishi, Y; Numata, K; Sannibale, V; Somiya, K; Takahashi, R; Tariq, H; Tsubono, K; Ugas, J; Viboud, N; Yamamoto, H; Yoda, T; Wang Chen Yang

2002-01-01

Several R and D programmes are ongoing to develop the next generation of interferometric gravitational wave detectors providing the superior sensitivity desired for refined astronomical observations. In order to obtain a wide observation band at low frequencies, the optics need to be isolated from the seismic noise. The TAMA SAS (seismic attenuation system) has been developed within an international collaboration between TAMA, LIGO, and some European institutes, with the main objective of achieving sufficient low-frequency seismic attenuation (-180 dB at 10 HZ). The system suppresses seismic noise well below the other noise levels starting at very low frequencies above 10 Hz. It also includes an active inertial damping system to decrease the residual motion of the optics enough to allow a stable operation of the interferometer. The TAMA SAS also comprises a sophisticated mirror suspension subsystem (SUS). The SUS provides support for the optics and vibration isolation complementing the SAS performance. The SU...

Surface anatomy scanning (SAS) in intracranial tumours: comparison with surgical findings

International Nuclear Information System (INIS)

Sumida, M.; Uozumi, T.; Kiya, K.; Arita, K.; Kurisu, K.; Onda, J.; Satoh, H.; Ikawa, F.; Yukawa, O.; Migita, K.; Hada, H.; Katada, K.

1995-01-01

We evaluated the usefulness of surface anatomy scanning (SAS) in intracranial tumours, comparing it with surgical findings. We examined 31 patients with brain tumours preoperatively. The tumours included 16 meningiomas, 8 gliomas, 4 metastases and 3 others. SAS clearly demonstrated the tumours, allowing them to be distinguished from the structures of the brain surface, including oedema, except in cases of metastasis. SAS clearly demonstrated large cortical veins. SAS is useful for three-dimensional delineation of the brain surface before surgery. (orig.)

Adaptive beamforming for low frequency SAS imagery and bathymetry

NARCIS (Netherlands)

Hayes, M.P.; Hunter, A.J.

2012-01-01

Synthetic aperture side-scan sonar (SAS) is a mature technology for high-resolution sea floor imaging [1]. Interferometric synthetic aperture sonars (InSAS) use additional hydrophones in a vertical array for bathymetric mapping [2]. This has created high-resolution bathymetry in deep water

First report of sasX-positive methicillin-resistant Staphylococcus aureus in Japan.

Science.gov (United States)

Nakaminami, Hidemasa; Ito, Teruyo; Han, Xiao; Ito, Ayumu; Matsuo, Miki; Uehara, Yuki; Baba, Tadashi; Hiramatsu, Keiichi; Noguchi, Norihisa

2017-09-01

SasX is a known virulence factor of Staphylococcus aureus involved in colonisation and immune evasion of the bacterium. The sasX gene, which is located on the ϕSPβ prophage, is frequently found in the sequence type (ST) 239 S. aureus lineage, which is the predominant healthcare-associated clone in Asian countries. In Japan, ST239 clones have rarely been identified, and sasX-positive strains have not been reported to date. Here, we report the first identification of 18 sasX-positive methicillin-resistant S. aureus (MRSA) strains in Japanese hospitals between 2009 and 2011. All sasX-positive isolates belonged to an ST239-staphylococcal cassette chromosome mec type III (ST239-III) lineage. However, we were unable to identify additional sasX-positive MRSA strains from 2012 to 2016, indicating that the small epidemic of sasX-positive isolates observed in this study was temporary. The sequence surrounding sasX in the strain TOHH628 lacked 51 genes that encode phage packaging and structural proteins, and no bacteriophage was induced by mitomycin C. Additionally, in the TOHH628 strain, the region (64.6 kb) containing sasX showed high identity to the ϕSPβ-like element (71.3 kb) of the Taiwanese MRSA strain Z172. The data strongly suggest that the present sasX-positive isolates found in Japanese hospitals were transmitted incidentally from other countries. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Development and validation of a smartphone addiction scale (SAS.

Directory of Open Access Journals (Sweden)

Min Kwon

Full Text Available OBJECTIVE: The aim of this study was to develop a self-diagnostic scale that could distinguish smartphone addicts based on the Korean self-diagnostic program for Internet addiction (K-scale and the smartphone's own features. In addition, the reliability and validity of the smartphone addiction scale (SAS was demonstrated. METHODS: A total of 197 participants were selected from Nov. 2011 to Jan. 2012 to accomplish a set of questionnaires, including SAS, K-scale, modified Kimberly Young Internet addiction test (Y-scale, visual analogue scale (VAS, and substance dependence and abuse diagnosis of DSM-IV. There were 64 males and 133 females, with ages ranging from 18 to 53 years (M = 26.06; SD = 5.96. Factor analysis, internal-consistency test, t-test, ANOVA, and correlation analysis were conducted to verify the reliability and validity of SAS. RESULTS: Based on the factor analysis results, the subscale "disturbance of reality testing" was removed, and six factors were left. The internal consistency and concurrent validity of SAS were verified (Cronbach's alpha = 0.967. SAS and its subscales were significantly correlated with K-scale and Y-scale. The VAS of each factor also showed a significant correlation with each subscale. In addition, differences were found in the job (p<0.05, education (p<0.05, and self-reported smartphone addiction scores (p<0.001 in SAS. CONCLUSIONS: This study developed the first scale of the smartphone addiction aspect of the diagnostic manual. This scale was proven to be relatively reliable and valid.

Hotelli Radisson SAS mantra : jah, ma saan! / Kai Vare

Index Scriptorium Estoniae

Vare, Kai, 1968-

2004-01-01

Radisson SAS hotell Tallinnas on kliendirahulolu-uuringute järgi keti hotellide seas esimeste hulgas. Hotelli direktor Kaido Ojaperv ja müügijuht Ann-Kai Tõrs Radisson SAS-i standarditest, kliendi sajaprotsendilise rahulolu tagamise põhimõtetest, personali valikust, koolitusest. Kommenteerib Sandra Dimitrovich

Structures of SAS-6 suggest its organization in centrioles.

Science.gov (United States)

van Breugel, Mark; Hirono, Masafumi; Andreeva, Antonina; Yanagisawa, Haru-aki; Yamaguchi, Shoko; Nakazawa, Yuki; Morgner, Nina; Petrovich, Miriana; Ebong, Ima-Obong; Robinson, Carol V; Johnson, Christopher M; Veprintsev, Dmitry; Zuber, Benoît

2011-03-04

Centrioles are cylindrical, ninefold symmetrical structures with peripheral triplet microtubules strictly required to template cilia and flagella. The highly conserved protein SAS-6 constitutes the center of the cartwheel assembly that scaffolds centrioles early in their biogenesis. We determined the x-ray structure of the amino-terminal domain of SAS-6 from zebrafish, and we show that recombinant SAS-6 self-associates in vitro into assemblies that resemble cartwheel centers. Point mutations are consistent with the notion that centriole formation in vivo depends on the interactions that define the self-assemblies observed here. Thus, these interactions are probably essential to the structural organization of cartwheel centers.

Development and validation of a smartphone addiction scale (SAS).

Science.gov (United States)

Kwon, Min; Lee, Joon-Yeop; Won, Wang-Youn; Park, Jae-Woo; Min, Jung-Ah; Hahn, Changtae; Gu, Xinyu; Choi, Ji-Hye; Kim, Dai-Jin

2013-01-01

The aim of this study was to develop a self-diagnostic scale that could distinguish smartphone addicts based on the Korean self-diagnostic program for Internet addiction (K-scale) and the smartphone's own features. In addition, the reliability and validity of the smartphone addiction scale (SAS) was demonstrated. A total of 197 participants were selected from Nov. 2011 to Jan. 2012 to accomplish a set of questionnaires, including SAS, K-scale, modified Kimberly Young Internet addiction test (Y-scale), visual analogue scale (VAS), and substance dependence and abuse diagnosis of DSM-IV. There were 64 males and 133 females, with ages ranging from 18 to 53 years (M = 26.06; SD = 5.96). Factor analysis, internal-consistency test, t-test, ANOVA, and correlation analysis were conducted to verify the reliability and validity of SAS. Based on the factor analysis results, the subscale "disturbance of reality testing" was removed, and six factors were left. The internal consistency and concurrent validity of SAS were verified (Cronbach's alpha = 0.967). SAS and its subscales were significantly correlated with K-scale and Y-scale. The VAS of each factor also showed a significant correlation with each subscale. In addition, differences were found in the job (psmartphone addiction scores (psmartphone addiction aspect of the diagnostic manual. This scale was proven to be relatively reliable and valid.

Napojení .NET / Java technologie na SAS BI

OpenAIRE

Jandák, Miroslav

2009-01-01

This thesis is focused on SAS Enterprise Intelligence Platform product and it's capabilities to integrate within a Business Intelligence solution. The aim of the thesis is to describe integration technolgies that the platform features, as well as to determine their application field and compare them, eventually add usage examples. The first part of the thesis explains the general concept and architecture of Business Intelligence, afterwards the reader gets familiar with the SAS Enterprise Int...

Statistical hypothesis testing with SAS and R

CERN Document Server

Taeger, Dirk

2014-01-01

A comprehensive guide to statistical hypothesis testing with examples in SAS and R When analyzing datasets the following questions often arise:Is there a short hand procedure for a statistical test available in SAS or R?If so, how do I use it?If not, how do I program the test myself? This book answers these questions and provides an overview of the most commonstatistical test problems in a comprehensive way, making it easy to find and performan appropriate statistical test. A general summary of statistical test theory is presented, along with a basicdescription for each test, including the

SAS macro programs for geographically weighted generalized linear modeling with spatial point data: applications to health research.

Science.gov (United States)

Chen, Vivian Yi-Ju; Yang, Tse-Chuan

2012-08-01

An increasing interest in exploring spatial non-stationarity has generated several specialized analytic software programs; however, few of these programs can be integrated natively into a well-developed statistical environment such as SAS. We not only developed a set of SAS macro programs to fill this gap, but also expanded the geographically weighted generalized linear modeling (GWGLM) by integrating the strengths of SAS into the GWGLM framework. Three features distinguish our work. First, the macro programs of this study provide more kernel weighting functions than the existing programs. Second, with our codes the users are able to better specify the bandwidth selection process compared to the capabilities of existing programs. Third, the development of the macro programs is fully embedded in the SAS environment, providing great potential for future exploration of complicated spatially varying coefficient models in other disciplines. We provided three empirical examples to illustrate the use of the SAS macro programs and demonstrated the advantages explained above. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Mirror suspension system for the TAMA SAS

International Nuclear Information System (INIS)

Takamori, Akiteru; Ando, Masaki; Bertolini, Alessandro; Cella, Giancarlo; DeSalvo, Riccardo; Fukushima, Mitsuhiro; Iida, Yukiyoshi; Jacquier, Florian; Kawamura, Seiji; Marka, Szabolcs; Nishi, Yuhiko; Numata, Kenji; Sannibale, Virginio; Somiya, Kentaro; Takahashi, Ryutaro; Tariq, Hareem; Tsubono, Kimio; Ugas, Jose; Viboud, Nicolas; Yamamoto, Hiroaki; Yoda, Tatsuo; Wang Chenyang

2002-01-01

Several R and D programmes are ongoing to develop the next generation of interferometric gravitational wave detectors providing the superior sensitivity desired for refined astronomical observations. In order to obtain a wide observation band at low frequencies, the optics need to be isolated from the seismic noise. The TAMA SAS (seismic attenuation system) has been developed within an international collaboration between TAMA, LIGO, and some European institutes, with the main objective of achieving sufficient low-frequency seismic attenuation (-180 dB at 10 HZ). The system suppresses seismic noise well below the other noise levels starting at very low frequencies above 10 Hz. It also includes an active inertial damping system to decrease the residual motion of the optics enough to allow a stable operation of the interferometer. The TAMA SAS also comprises a sophisticated mirror suspension subsystem (SUS). The SUS provides support for the optics and vibration isolation complementing the SAS performance. The SUS is equipped with a totally passive magnetic damper to suppress internal resonances without degrading the thermal noise performance. In this paper we discuss the SUS details and present prototype results

Categorical Data Analysis With Sas and Spss Applications

CERN Document Server

Lawal, H Bayo

2003-01-01

This book covers the fundamental aspects of categorical data analysis with an emphasis on how to implement the models used in the book using SAS and SPSS. This is accomplished through the frequent use of examples, with relevant codes and instructions, that are closely related to the problems in the text. Concepts are explained in detail so that students can reproduce similar results on their own. Beginning with chapter two, exercises at the end of each chapter further strengthen students' understanding of the concepts by requiring them to apply some of the ideas expressed in the text in a more

Exploring item and higher order factor structure with the Schmid-Leiman solution: syntax codes for SPSS and SAS.

Science.gov (United States)

Wolff, Hans-Georg; Preising, Katja

2005-02-01

To ease the interpretation of higher order factor analysis, the direct relationships between variables and higher order factors may be calculated by the Schmid-Leiman solution (SLS; Schmid & Leiman, 1957). This simple transformation of higher order factor analysis orthogonalizes first-order and higher order factors and thereby allows the interpretation of the relative impact of factor levels on variables. The Schmid-Leiman solution may also be used to facilitate theorizing and scale development. The rationale for the procedure is presented, supplemented by syntax codes for SPSS and SAS, since the transformation is not part of most statistical programs. Syntax codes may also be downloaded from www.psychonomic.org/archive/.

A SAS2H/KENO-V methodology for 3D fuel burnup analysis

International Nuclear Information System (INIS)

Milosevic, M.; Greenspan, E.; Vujic, J.

2002-01-01

An efficient methodology for 3D fuel burnup analysis of LWR reactors is described in this paper. This methodology is founded on coupling Monte Carlo method for 3D calculation of node power distribution, and transport method for depletion calculation in ID Wigner-Seitz equivalent cell for each node independently. The proposed fuel burnup modeling, based on application of SCALE-4.4a control modules SAS2H and KENO-V.a is verified for the case of 2D x-y model of IRIS 15 x 15 fuel assembly (with reflective boundary condition) by using two well benchmarked code systems. The one is MOCUP, a coupled MCNP-4C and ORIGEN2.1 utility code, and the second is KENO-V.a/ORIGEN2.1 code system recently developed by authors of this paper. The proposed SAS2H/KENO-V.a methodology was applied for 3D burnup analysis of IRIS-1000 benchmark.44 core. Detailed k sub e sub f sub f and power density evolution with burnup are reported. (author)

SAS-macros for estimation and prediction in an model of the electricity consumption

DEFF Research Database (Denmark)

1998-01-01

SAS-macros for estimation and prediction in an model of the electricity consumption'' is a large collection of SAS-macros for handling a model of the electricity consumption in the Eastern Denmark. The macros are installed at Elkraft, Ballerup.......SAS-macros for estimation and prediction in an model of the electricity consumption'' is a large collection of SAS-macros for handling a model of the electricity consumption in the Eastern Denmark. The macros are installed at Elkraft, Ballerup....

OECD benchmark a of MOX fueled PWR unit cells using SAS2H, triton and mocup

International Nuclear Information System (INIS)

Ganda, F.; Greenspan, A.

2005-01-01

Three code systems are tested by applying them to calculate the OECD PWR MOX unit cell benchmark A. The codes tested are the SAS2H code sequence of the SCALE5 code package using 44 group library, MOCUP (MCNP4C + ORIGEN2), and the new TRITON depletion sequence of SCALE5 using 238 group cross sections generated using CENTRM with continuous energy cross sections. The burnup-dependent k ∞ and actinides concentration calculated by all three code-systems were found to be in good agreement with the OECD benchmark average results. Limited results were calculated also with the WIMS-ANL code package. WIMS-ANL was found to significantly under-predict k ∞ as well as the concentration of Pu 242 , consistently with the predictions of the WIMS-LWR reported by two of the OECD benchmark participants. Additionally, SAS2H is benchmarked against MOCUP for a hydride fuel containing unit cell, giving very satisfactory agreement. (authors)

Fitting polytomous Rasch models in SAS

DEFF Research Database (Denmark)

Christensen, Karl Bang

2006-01-01

The item parameters of a polytomous Rasch model can be estimated using marginal and conditional approaches. This paper describes how this can be done in SAS (V8.2) for three item parameter estimation procedures: marginal maximum likelihood estimation, conditional maximum likelihood estimation, an...

Olev Schults : SAS vajab Estonian Airi rahvusliku lennufirmana / Olev Schults ; interv. Andres Reimer

Index Scriptorium Estoniae

Schults, Olev

2008-01-01

Estonian Airi nõukogu esimees vastab küsimustele, kas SAS arendas Läti airBalticut Estonian SAS-i arvel, mis mõte on rahvuslikul lennukompaniil, kui riik ei tohi seda finantseerida, kuidas mõjutab investorite meeleolu SAS-i Eestis tabanud poliitikute kriitika tulv

Nyheder i SAS Analytics 14.2

DEFF Research Database (Denmark)

Milhøj, Anders

2017-01-01

I november 2016 blev Analytical Produts i den opdaterede version 14.2 sendt på markedet. Denne opdatering indeholder opdateringer af de analytiske programpakker inden for statistik, økonometri, operationsanalyse etc. Disse opdateringer er nu løsrevet fra samtidige opdateringer af det samlede SAS-program...

Model development of SAS4A and investigation on the initiating phase consequences in LMFRs related with material motion

International Nuclear Information System (INIS)

Niwa, H.

1994-01-01

This paper focuses on an analytical aspect of the initiating phase scenario and consequences of postulated core disruptive accident in liquid-metal-cooled fast breeder reactors. An analytical code, SAS4A, has been developed at Argonne National Laboratory, and introduced to PNC. Improvement and validation effort have been performed for the mixed-oxide version of SAS4A at PNC. This paper describes firstly recent development of SAS4A's material motion related models briefly. A fission gas mass transfer model and solid fuel chunk jamming model are developed and introduced to SAS4A, and validated using CABRI-2 E13 experimental data. Secondly, an investigation of the mechanism of energetics in the initiating phase of an unprotected loss-of-flow accident has identified major control parameters which are intimately related to core design parameters and material motion phenomena. (author)

Melnās krāsas iespējas interjerā

OpenAIRE

Lapkovska, Ērika

2016-01-01

Diplomdarbā “Melnās krāsas iespējas interjerā”, analizējot pieejamo literatūru, tiek apskatīta melnās krāsas izpratne, nozīme un lietojums vēsturiskā skatījumā, kā arī melnās krāsas izmantojuma principi interjerā. Empīriskajā daļā tiek veikts salīdzinošais pētījums, analizējot dažādus kafejnīcu un bāru interjerus Latvijā un pasaulē, kuros ir melnās krāsas klātbūtne. Diplomdarba apjoms – 75 lpp., kurās iekļauts ievads, 4 nodaļas, 7 apakšnodaļas, literatūras saraksts ar 53 vienībām, 2 pielikum...

A SAS/AF application to administrate and query a file of incidents occurring in foreign nuclear power plants

International Nuclear Information System (INIS)

Durbec, V.

1994-07-01

The Research and Development Division of Electricite de France has a file of incidents occurring in foreign pressurized water nuclear power stations. These incidents have an impact either on safety or reliability. The file is stored on an IBM 3090. For each incident, a docket is assigned, containing the identity of the nuclear plant and information in the form of code or text on the incident. An application has been built with the SAS System under IBM (MVS) in order to: - allow the input of new nuclear plant identities, monthly operating coefficients and new incidents; - subset data from each SAS data set, according to selection criteria (country, manufacturers, period, materials, etc...) in the form of coded fields and characters strings; -calculate simple statistical analyses on subset data (histograms of break duration, distribution of operating coefficients, cross-tabulation tables of sets and materials which bring about the incident) with a restitution on screen and/or printer; - edit an annual booklet containing general results of functioning of plants. After validation, data retrieved from the database are used in probabilistic safety analysis of nuclear power plants and materials designing studies (comparison with French materials, identification of factors having an impact on performance). The application is an interactive menu-driven tool and contains data entry screens (for new data or selection criteria). These screens have been built with SAS/AF software and Screen Control Language. Data selection and processing have been developed with Base SAS and SAS/GRAPH software. (author). 1 ref., 6 figs., 2 tabs

Combination of functional MRI with SAS and MRA

Energy Technology Data Exchange (ETDEWEB)

Sumida, Masayuki; Takeshita, Shinichirou; Kutsuna, Munenori; Akimitsu, Tomohide; Arita, Kazunori; Kurisu, Kaoru [Hiroshima Univ. (Japan). School of Medicine

1999-02-01

For presurgical diagnosis of brain surface, combination of functional MRI (fMRI) with the MR angiography was examined. This method could visualize brain bay, convolution and vein as index of surface. Five normal adults (male, mean age: 28-year-old) and 7 patients with brain tumor on the main locus to surface (male: 4, female: 3, mean age: 52.3-year-old) were studied. fMRI was performed by SPGR method (TR 70, TE 40, flip angle 60, one slice, thickness 10 mm, FOV 20 cm, matrix 128 x 128). The brain surface was visualized by SAS (surface anatomy scanning). SAS was performed by FSE method (TR 6000, TE 200, echo train 16, thickness 20 mm, slice 3, NEX 2). Cortical veins near superior sagittal sinus were visualized by MRA with 2D-TOF method (TR 50, TE 20, flip angle 60, thickness 2 mm, slice 28, NEX 1). These images were superimposed and functional image of peripheral sensorimotor region was evaluated anatomically. In normal adults, high signal was visualized at another side of near sensorimotor region at 8 of 10 sides. All high signal area of fMRI agreed with cortical vein near sensorimotor region that was visualized by MRA. In patients with brain tumor, signal was visualized at another side of sensorimotor region of tumor without 2 cases with palsy. In another side of tumor, signal of fMRI was visualized in 5 of 7 cases. The tumor was visualized as opposite low signal field in SAS. Locational relation between tumor and brain surface and brain function was visualized distinctly by combination of MRA, SAS and MRA. This method could become useful for presurgical diagnosis. (K.H.)

SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture.

Science.gov (United States)

Hilbert, Manuel; Noga, Akira; Frey, Daniel; Hamel, Virginie; Guichard, Paul; Kraatz, Sebastian H W; Pfreundschuh, Moritz; Hosner, Sarah; Flückiger, Isabelle; Jaussi, Rolf; Wieser, Mara M; Thieltges, Katherine M; Deupi, Xavier; Müller, Daniel J; Kammerer, Richard A; Gönczy, Pierre; Hirono, Masafumi; Steinmetz, Michel O

2016-04-01

Centrioles are critical for the formation of centrosomes, cilia and flagella in eukaryotes. They are thought to assemble around a nine-fold symmetric cartwheel structure established by SAS-6 proteins. Here, we have engineered Chlamydomonas reinhardtii SAS-6-based oligomers with symmetries ranging from five- to ten-fold. Expression of a SAS-6 mutant that forms six-fold symmetric cartwheel structures in vitro resulted in cartwheels and centrioles with eight- or nine-fold symmetries in vivo. In combination with Bld10 mutants that weaken cartwheel-microtubule interactions, this SAS-6 mutant produced six- to eight-fold symmetric cartwheels. Concurrently, the microtubule wall maintained eight- and nine-fold symmetries. Expressing SAS-6 with analogous mutations in human cells resulted in nine-fold symmetric centrioles that exhibited impaired length and organization. Together, our data suggest that the self-assembly properties of SAS-6 instruct cartwheel symmetry, and lead us to propose a model in which the cartwheel and the microtubule wall assemble in an interdependent manner to establish the native architecture of centrioles.

Sas-4 proteins are required during basal body duplication in Paramecium

Science.gov (United States)

Gogendeau, Delphine; Hurbain, Ilse; Raposo, Graca; Cohen, Jean; Koll, France; Basto, Renata

2011-01-01

Centrioles and basal bodies are structurally related organelles composed of nine microtubule (MT) triplets. Studies performed in Caenorhabditis elegans embryos have shown that centriole duplication takes place in sequential way, in which different proteins are recruited in a specific order to assemble a procentriole. ZYG-1 initiates centriole duplication by triggering the recruitment of a complex of SAS-5 and SAS-6, which then recruits the final player, SAS-4, to allow the incorporation of MT singlets. It is thought that a similar mechanism (that also involves additional proteins) is present in other animal cells, but it remains to be investigated whether the same players and their ascribed functions are conserved during basal body duplication in cells that exclusively contain basal bodies. To investigate this question, we have used the multiciliated protist Paramecium tetraurelia. Here we show that in the absence of PtSas4, two types of defects in basal body duplication can be identified. In the majority of cases, the germinative disk and cartwheel, the first structures assembled during duplication, are not detected. In addition, if daughter basal bodies were formed, they invariably had defects in MT recruitment. Our results suggest that PtSas4 has a broader function than its animal orthologues. PMID:21289083

SAS-6 assembly templated by the lumen of cartwheel-less centrioles precedes centriole duplication.

Science.gov (United States)

Fong, Chii Shyang; Kim, Minhee; Yang, T Tony; Liao, Jung-Chi; Tsou, Meng-Fu Bryan

2014-07-28

Centrioles are 9-fold symmetric structures duplicating once per cell cycle. Duplication involves self-oligomerization of the centriolar protein SAS-6, but how the 9-fold symmetry is invariantly established remains unclear. Here, we found that SAS-6 assembly can be shaped by preexisting (or mother) centrioles. During S phase, SAS-6 molecules are first recruited to the proximal lumen of the mother centriole, adopting a cartwheel-like organization through interactions with the luminal wall, rather than via their self-oligomerization activity. The removal or release of luminal SAS-6 requires Plk4 and the cartwheel protein STIL. Abolishing either the recruitment or the removal of luminal SAS-6 hinders SAS-6 (or centriole) assembly at the outside wall of mother centrioles. After duplication, the lumen of engaged mother centrioles becomes inaccessible to SAS-6, correlating with a block for reduplication. These results lead to a proposed model that centrioles may duplicate via a template-based process to preserve their geometry and copy number. Copyright © 2014 Elsevier Inc. All rights reserved.

Social Analysis Systems (SAS2) - Phase III

International Development Research Centre (IDRC) Digital Library (Canada)

Scaling Up the International Impact of Action Research : Social Analysis ... up the international impact of action research : SAS phase 3; final technical report ... 000 Canadians abroad to work at the local level on various development issues.

SPSS and SAS programs for comparing Pearson correlations and OLS regression coefficients.

Science.gov (United States)

Weaver, Bruce; Wuensch, Karl L

2013-09-01

Several procedures that use summary data to test hypotheses about Pearson correlations and ordinary least squares regression coefficients have been described in various books and articles. To our knowledge, however, no single resource describes all of the most common tests. Furthermore, many of these tests have not yet been implemented in popular statistical software packages such as SPSS and SAS. In this article, we describe all of the most common tests and provide SPSS and SAS programs to perform them. When they are applicable, our code also computes 100 × (1 - α)% confidence intervals corresponding to the tests. For testing hypotheses about independent regression coefficients, we demonstrate one method that uses summary data and another that uses raw data (i.e., Potthoff analysis). When the raw data are available, the latter method is preferred, because use of summary data entails some loss of precision due to rounding.

WinBUGSio: A SAS Macro for the Remote Execution of WinBUGS

Directory of Open Access Journals (Sweden)

Michael K. Smith

2007-09-01

Full Text Available This is a macro which facilitates remote execution of WinBUGS from within SAS. The macro pre-processes data for WinBUGS, writes the WinBUGS batch-script, executes this script and reads in output statistics from the WinBUGS log-file back into SAS native format. The user specifies the input and output file names and directory path as well as the statistics to be monitored in WinBUGS. The code works best for a model that has already been set up and checked for convergence diagnostics within WinBUGS. An obvious extension of the use of this macro is for running simulations where the input and output files all have the same name but all that differs between simulation iterations is the input dataset. The functionality and syntax of the macro call are described in this paper and illustrated using a simple linear regression model.

Comparison of SAS3A and MELT-III predictions for a transient overpower hypothetical accident

International Nuclear Information System (INIS)

Wilburn, N.P.

1976-01-01

A comparison is made of the predictions of the two major codes SAS3A and MELT-III for the hypothetical unprotected transient overpower accident in the FFTF. The predictions of temperatures, fuel restructuring, fuel melting, reactivity feedbacks, and core power are compared

[A SAS marco program for batch processing of univariate Cox regression analysis for great database].

Science.gov (United States)

Yang, Rendong; Xiong, Jie; Peng, Yangqin; Peng, Xiaoning; Zeng, Xiaomin

2015-02-01

To realize batch processing of univariate Cox regression analysis for great database by SAS marco program. We wrote a SAS macro program, which can filter, integrate, and export P values to Excel by SAS9.2. The program was used for screening survival correlated RNA molecules of ovarian cancer. A SAS marco program could finish the batch processing of univariate Cox regression analysis, the selection and export of the results. The SAS macro program has potential applications in reducing the workload of statistical analysis and providing a basis for batch processing of univariate Cox regression analysis.

The Prospects of SAS Interferometry for Detection and Classification (SAS Interferometrie voor Detectie en Classificatie)

Science.gov (United States)

2008-10-01

DV2008A176 Opdrachtnummer Datum October 2008 Auteur (s) dr. R. van Vossen B.A.J. Quesson dr.ir. J.C. Sabel Rubricering rapport Ongerubriceerd TH9...TNO report | TNO-DV 2008 A176 4/44 Summary This report presents an overview of the theory and implementation of interferometric SAS processing at TNO... theory in software has been tested on two types of data, simulated and measured. Chapter 3 presents results obtained with simulated data; Chapter 4

DEFORM-4: fuel pin characterization and transient response in the SAS4A accident analysis code system

International Nuclear Information System (INIS)

Miles, K.J.; Hill, D.J.

1986-01-01

The DEFORM-4 module is the segment of the SAS4A Accident Analysis Code System that calculates the fuel pin characterization in response to a steady state irradiation history, thereby providing the initial conditions for the transient calculation. The various phenomena considered include fuel porosity migration, fission gas bubble induced swelling, fuel cracking and healing, fission gas release, cladding swelling, and the thermal-mechanical state of the fuel and cladding. In the transient state, the module continues the thermal-mechanical response calculation, including fuel melting and central cavity pressurization, until cladding failure is predicted and one of the failed fuel modules is initiated. Comparisons with experimental data have demonstrated the validity of the modeling approach

SAS- Semantic Annotation Service for Geoscience resources on the web

Science.gov (United States)

Elag, M.; Kumar, P.; Marini, L.; Li, R.; Jiang, P.

2015-12-01

There is a growing need for increased integration across the data and model resources that are disseminated on the web to advance their reuse across different earth science applications. Meaningful reuse of resources requires semantic metadata to realize the semantic web vision for allowing pragmatic linkage and integration among resources. Semantic metadata associates standard metadata with resources to turn them into semantically-enabled resources on the web. However, the lack of a common standardized metadata framework as well as the uncoordinated use of metadata fields across different geo-information systems, has led to a situation in which standards and related Standard Names abound. To address this need, we have designed SAS to provide a bridge between the core ontologies required to annotate resources and information systems in order to enable queries and analysis over annotation from a single environment (web). SAS is one of the services that are provided by the Geosematnic framework, which is a decentralized semantic framework to support the integration between models and data and allow semantically heterogeneous to interact with minimum human intervention. Here we present the design of SAS and demonstrate its application for annotating data and models. First we describe how predicates and their attributes are extracted from standards and ingested in the knowledge-base of the Geosemantic framework. Then we illustrate the application of SAS in annotating data managed by SEAD and annotating simulation models that have web interface. SAS is a step in a broader approach to raise the quality of geoscience data and models that are published on the web and allow users to better search, access, and use of the existing resources based on standard vocabularies that are encoded and published using semantic technologies.

Want independent validation and assurance? Ask for a SAS-70.

Science.gov (United States)

Boutin, Christopher C

2008-08-01

The AICPA's Statement on Auditing Standards No.70, Service Organizations addresses CPA audits of service providers conducted to verify that a provider has adequate controls over its operations. Hospitals should request a SAS-70, the report produced by such an audit, from all of their third-party service providers. SAS-70s can be issued for a specific date or for a six-month period, and they typically consist of three sections: a CPA opinion, a description of controls, and information about the design of the controls.

Handling missing data in cluster randomized trials: A demonstration of multiple imputation with PAN through SAS

Directory of Open Access Journals (Sweden)

Jiangxiu Zhou

2014-09-01

Full Text Available The purpose of this study is to demonstrate a way of dealing with missing data in clustered randomized trials by doing multiple imputation (MI with the PAN package in R through SAS. The procedure for doing MI with PAN through SAS is demonstrated in detail in order for researchers to be able to use this procedure with their own data. An illustration of the technique with empirical data was also included. In this illustration thePAN results were compared with pairwise deletion and three types of MI: (1 Normal Model (NM-MI ignoring the cluster structure; (2 NM-MI with dummy-coded cluster variables (fixed cluster structure; and (3 a hybrid NM-MI which imputes half the time ignoring the cluster structure, and the other half including the dummy-coded cluster variables. The empirical analysis showed that using PAN and the other strategies produced comparable parameter estimates. However, the dummy-coded MI overestimated the intraclass correlation, whereas MI ignoring the cluster structure and the hybrid MI underestimated the intraclass correlation. When compared with PAN, the p-value and standard error for the treatment effect were higher with dummy-coded MI, and lower with MI ignoring the clusterstructure, the hybrid MI approach, and pairwise deletion. Previous studies have shown that NM-MI is not appropriate for handling missing data in clustered randomized trials. This approach, in addition to the pairwise deletion approach, leads to a biased intraclass correlation and faultystatistical conclusions. Imputation in clustered randomized trials should be performed with PAN. We have demonstrated an easy way for using PAN through SAS.

Adaptation of XMM-Newton SAS to GRID and VO architectures via web

Science.gov (United States)

Ibarra, A.; de La Calle, I.; Gabriel, C.; Salgado, J.; Osuna, P.

2008-10-01

The XMM-Newton Scientific Analysis Software (SAS) is a robust software that has allowed users to produce good scientific results since the beginning of the mission. This has been possible given the SAS capability to evolve with the advent of new technologies and adapt to the needs of the scientific community. The prototype of the Remote Interface for Science Analysis (RISA) presented here, is one such example, which provides remote analysis of XMM-Newton data with access to all the existing SAS functionality, while making use of GRID computing technology. This new technology has recently emerged within the astrophysical community to tackle the ever lasting problem of computer power for the reduction of large amounts of data.

Airbus A320 NEO Base Maintenance Concept SAS Operations

OpenAIRE

Dafgård, Oscar

2017-01-01

Detta arbete har utförts tillsammans med SAS, för att undersöka om ett base maintenance koncept med ett intervall på 36 månader skulle vara mer kostnadseffektivt än 24 månader för deras nya Airbus A320 NEO flotta. SAS, precis som alla andra flygbolag utnyttjar sina flygplan på sina egna och specifika vis. Eftersom inga flygbolag opererar på samma sätt kan inte heller underhållet skötas på samma sätt för en specifik flygplanstyp. Underhållsprogrammet behövde därför ses över för att optimeras g...

Analysis of the TREAT loss-of-flow tests L6 and L7 using SAS3D

International Nuclear Information System (INIS)

Morris, E.E.; Simms, R.; Gruber, E.E.

1985-01-01

The TREAT loss-of-flow tests L6 and L7 have been analyzed using the SAS3D accident analysis code. The impetus for the analysis was the need for experimentally supported fuel motion modeling in whole core accident studies performed in support of licensing of the Clinch River Breeder Reactor Project. The input prescription chosen for the SAS3D/SLUMPY fuel motion model gave reasonable agreement with the test results. Tests L6 and L7, each conducted with a cluster of three fuel pins, were planned to simulate key events in the loss-of-flow accident scenario for the Clinch River homogeneous reactor

SAS tahab Estonian Airi liita lätlaste firmaga airBaltic / Andres Eilart

Index Scriptorium Estoniae

Eilart, Andres

2007-01-01

SAS plaanib Estonian Airi ja Läti firma airBalticu liitmisega luua uue lennufirma. Autori hinnangul viitavad Estonian Airi laienemisplaanidele kriipsu peale tõmbamine ja SAS-i investeeringud airBalticusse sellele, et ühendamise käigus "neelab" Läti firma Estonian Airi

SAS üritab panna riiki lennufirma aktsiaid müüma / Lemmi Kann

Index Scriptorium Estoniae

Kann, Lemmi

2007-01-01

SAS-i eesmärgiks on saada enamusosalus nii Estonian Airis kui ka airBalticus, et seeläbi oma positsioone Baltimaades kinnistada. Diagramm: Estonian Airi majandusnäitajad ja omanikud. Vt. samas: SAS on Estonian Airi jahtinud kaua. Kommenteerib Raivo Vare

Utilization of the RELAP4/MOD5/SAS code version in loss of coolant accident in the Angra 1 nuclear power station

International Nuclear Information System (INIS)

Sabundjian, G.; Freitas, R.L.

1991-09-01

A new version of computer code RELAP4/MOD5 was developed to improve the output. The new version, called RELAP4/MOD5/SAS, prints the main variables in graphical form. In order to check the program, a 36 - volume simulation of the Loss-of-Coolant Accident for Angra - I was performed and the results compared to those of a existing 44 - volume simulation showed a satisfactory agreement with a substantial reduction in computing time. (author)

Aging-Resistant Functionalized LDH⁻SAS/Nitrile-Butadiene Rubber Composites: Preparation and Study of Aging Kinetics/Anti-Aging Mechanism.

Science.gov (United States)

Li, Tianxiang; Shi, Zhengren; He, Xianru; Jiang, Ping; Lu, Xiaobin; Zhang, Rui; Wang, Xin

2018-05-18

With the aim of improving the anti-aging properties of nitrile-butadiene rubber (NBR), a functional organic filler, namely LDH⁻SAS, prepared by intercalating 4-amino-benzenesulfonic acid monosodium salt (SAS) into layered double hydroxides (LDHs) through anion exchange, was added to nitrile-butadiene rubber (NBR), giving the NBR/LDH⁻SAS composites. Successful preparation of LDH⁻SAS was confirmed by XRD, TGA and FTIR. LDH⁻SAS was well dispersed in the NBR matrix, owing to its strong interaction with the nitrile group of NBR. The obtained NBR/LDH⁻SAS composites exhibited excellent thermo-oxidative aging resistance as shown by TGA-DSC. Further investigation by ATR-FTIR indicated that SAS can capture the radical groups, even during the aging process, which largely accounts for the improved aging resistance.

Essentials of Excel, Excel VBA, SAS and Minitab for statistical and financial analyses

CERN Document Server

Lee, Cheng-Few; Chang, Jow-Ran; Tai, Tzu

2016-01-01

This introductory textbook for business statistics teaches statistical analysis and research methods via business case studies and financial data using Excel, MINITAB, and SAS. Every chapter in this textbook engages the reader with data of individual stock, stock indices, options, and futures. One studies and uses statistics to learn how to study, analyze, and understand a data set of particular interest. Some of the more popular statistical programs that have been developed to use statistical and computational methods to analyze data sets are SAS, SPSS, and MINITAB. Of those, we look at MINITAB and SAS in this textbook. One of the main reasons to use MINITAB is that it is the easiest to use among the popular statistical programs. We look at SAS because it is the leading statistical package used in industry. We also utilize the much less costly and ubiquitous Microsoft Excel to do statistical analysis, as the benefits of Excel have become widely recognized in the academic world and its analytical capabilities...

Development and application of the automated Monte Carlo biasing procedure in SAS4

International Nuclear Information System (INIS)

Tang, J.S.; Broadhead, B.L.

1995-01-01

An automated approach for biasing Monte Carlo shielding calculations is described. In particular, adjoint fluxes from a one-dimensional discrete-ordinates calculation are used to generate biasing parameters for a three-dimensional Monte Carlo calculation. The automated procedure consisting of cross-section processing, adjoint flux determination, biasing parameter generation, and the initiation of a MORSE-SGC/S Monte Carlo calculation has been implemented in the SAS4 module of the SCALE computer code system. (author)

Modification of the SAS4A Safety Analysis Code for Integration with the ADAPT Discrete Dynamic Event Tree Framework.

Energy Technology Data Exchange (ETDEWEB)

Jankovsky, Zachary Kyle [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Denman, Matthew R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2017-05-01

It is difficult to assess the consequences of a transient in a sodium-cooled fast reactor (SFR) using traditional probabilistic risk assessment (PRA) methods, as numerous safety-related sys- tems have passive characteristics. Often there is significant dependence on the value of con- tinuous stochastic parameters rather than binary success/failure determinations. One form of dynamic PRA uses a system simulator to represent the progression of a transient, tracking events through time in a discrete dynamic event tree (DDET). In order to function in a DDET environment, a simulator must have characteristics that make it amenable to changing physical parameters midway through the analysis. The SAS4A SFR system analysis code did not have these characteristics as received. This report describes the code modifications made to allow dynamic operation as well as the linking to a Sandia DDET driver code. A test case is briefly described to demonstrate the utility of the changes.

Aging-Resistant Functionalized LDH–SAS/Nitrile-Butadiene Rubber Composites: Preparation and Study of Aging Kinetics/Anti-Aging Mechanism

Science.gov (United States)

Li, Tianxiang; Shi, Zhengren; He, Xianru; Jiang, Ping; Lu, Xiaobin; Zhang, Rui

2018-01-01

With the aim of improving the anti-aging properties of nitrile-butadiene rubber (NBR), a functional organic filler, namely LDH–SAS, prepared by intercalating 4-amino-benzenesulfonic acid monosodium salt (SAS) into layered double hydroxides (LDHs) through anion exchange, was added to nitrile-butadiene rubber (NBR), giving the NBR/LDH–SAS composites. Successful preparation of LDH–SAS was confirmed by XRD, TGA and FTIR. LDH–SAS was well dispersed in the NBR matrix, owing to its strong interaction with the nitrile group of NBR. The obtained NBR/LDH–SAS composites exhibited excellent thermo-oxidative aging resistance as shown by TGA-DSC. Further investigation by ATR-FTIR indicated that SAS can capture the radical groups, even during the aging process, which largely accounts for the improved aging resistance. PMID:29783656

SAS-1 Is a C2 Domain Protein Critical for Centriole Integrity in C. elegans

Science.gov (United States)

Delattre, Marie; Balestra, Fernando R.; Blanchoud, Simon; Finger, Susanne; Knott, Graham; Müller-Reichert, Thomas; Gönczy, Pierre

2014-01-01

Centrioles are microtubule-based organelles important for the formation of cilia, flagella and centrosomes. Despite progress in understanding the underlying assembly mechanisms, how centriole integrity is ensured is incompletely understood, including in sperm cells, where such integrity is particularly critical. We identified C. elegans sas-1 in a genetic screen as a locus required for bipolar spindle assembly in the early embryo. Our analysis reveals that sperm-derived sas-1 mutant centrioles lose their integrity shortly after fertilization, and that a related defect occurs when maternal sas-1 function is lacking. We establish that sas-1 encodes a C2 domain containing protein that localizes to centrioles in C. elegans, and which can bind and stabilize microtubules when expressed in human cells. Moreover, we uncover that SAS-1 is related to C2CD3, a protein required for complete centriole formation in human cells and affected in a type of oral-facial-digital (OFD) syndrome. PMID:25412110

SAS-1 is a C2 domain protein critical for centriole integrity in C. elegans.

Directory of Open Access Journals (Sweden)

Lukas von Tobel

2014-11-01

Full Text Available Centrioles are microtubule-based organelles important for the formation of cilia, flagella and centrosomes. Despite progress in understanding the underlying assembly mechanisms, how centriole integrity is ensured is incompletely understood, including in sperm cells, where such integrity is particularly critical. We identified C. elegans sas-1 in a genetic screen as a locus required for bipolar spindle assembly in the early embryo. Our analysis reveals that sperm-derived sas-1 mutant centrioles lose their integrity shortly after fertilization, and that a related defect occurs when maternal sas-1 function is lacking. We establish that sas-1 encodes a C2 domain containing protein that localizes to centrioles in C. elegans, and which can bind and stabilize microtubules when expressed in human cells. Moreover, we uncover that SAS-1 is related to C2CD3, a protein required for complete centriole formation in human cells and affected in a type of oral-facial-digital (OFD syndrome.

Anatomy of the TAMA SAS seismic attenuation system

International Nuclear Information System (INIS)

Marka, Szabolcs; Takamori, Akiteru; Ando, Masaki; Bertolini, Alessandro; Cella, Giancarlo; DeSalvo, Riccardo; Fukushima, Mitsuhiro; Iida, Yukiyoshi; Jacquier, Florian; Kawamura, Seiji; Nishi, Yuhiko; Numata, Kenji; Sannibale, Virginio; Somiya, Kentaro; Takahashi, Ryutaro; Tariq, Hareem; Tsubono, Kimio; Ugas, Jose; Viboud, Nicolas; Wang Chenyang; Yamamoto, Hiroaki; Yoda, Tatsuo

2002-01-01

The TAMA SAS seismic attenuation system was developed to provide the extremely high level of seismic isolation required by the next generation of interferometric gravitational wave detectors to achieve the desired sensitivity at low frequencies. Our aim was to provide good performance at frequencies above ∼10 Hz, while utilizing only passive subsystems in the sensitive frequency band of the TAMA interferometric gravitational wave detectors. The only active feedback is relegated below 6 Hz and it is used to damp the rigid body resonances of the attenuation chain. Simulations, based on subsystem performance characterizations, indicate that the system can achieve rms mirror residual motion measured in a few tens of nanometres. We will give a brief overview of the subsystems and point out some of the characterization results, supporting our claims of achieved performance. SAS is a passive, UHV compatible and low cost system. It is likely that extremely sensitive experiments in other fields will also profit from our study

C-C1-04: How to Win Friends and Influence People with the SAS Output Delivery System

Science.gov (United States)

Tolbert, William

2010-01-01

Background and Aims: Long-time SAS users remember the days when SAS output was embarrassingly ugly. Version 7 saw the introduction of the Output Delivery System (ODS). ODS has matured into a very capable subsystem that gives users powerful reporting options. This presentation will highlight useful features and outline a macro-based system for handling multiple ODS destinations simultaneously. Nowadays there is no excuse for ugly SAS output! When building reports, SAS users should think about the needs of those using the reports. Some people just want to review frequency tables, and are happy to do so on a monitor. Others want to be able to print data for review in a meeting. And, there are always those that want to work with the data in a spreadsheet. Consider the ideal formats for each of the users outlined above. For the casual data browser, HTML output is ideal. For printing, PDF is preferred. And for the additional analysis, Excel is a popular option. With ODS, we can meet all of these needs. Methods: Because ODS permits opening multiple output destinations simultaneously, a single procedure can be used to generate data in HTML, PDF, and Excel at once. The presentation will demonstrate the following: o- basic ODS syntax for HTML, PDF, and Excel output o- custom HTML table of contents o- using the ExcelXP tagset for multi-tab spreadsheets o- a custom macro for managing multiple ODS destinations simultaneously o- simple PROC Template code for easy customization o- techniques for consistent output from multiple platforms. Results: The techniques outlined here have been well-received in a variety of business reporting environments. Conclusions: The SAS ODS provides a wide array of reporting options. Don’t limit yourself to just one type of output.

Ambiguities and completeness of SAS data analysis: investigations of apoferritin by SAXS/SANS EID and SEC-SAXS methods

Science.gov (United States)

Zabelskii, D. V.; Vlasov, A. V.; Ryzhykau, Yu L.; Murugova, T. N.; Brennich, M.; Soloviov, D. V.; Ivankov, O. I.; Borshchevskiy, V. I.; Mishin, A. V.; Rogachev, A. V.; Round, A.; Dencher, N. A.; Büldt, G.; Gordeliy, V. I.; Kuklin, A. I.

2018-03-01

The method of small angle scattering (SAS) is widely used in the field of biophysical research of proteins in aqueous solutions. Obtaining low-resolution structure of proteins is still a highly valuable method despite the advances in high-resolution methods such as X-ray diffraction, cryo-EM etc. SAS offers the unique possibility to obtain structural information under conditions close to those of functional assays, i.e. in solution, without different additives, in the mg/mL concentration range. SAS method has a long history, but there are still many uncertainties related to data treatment. We compared 1D SAS profiles of apoferritin obtained by X-ray diffraction (XRD) and SAS methods. It is shown that SAS curves for X-ray diffraction crystallographic structure of apoferritin differ more significantly than it might be expected due to the resolution of the SAS instrument. Extrapolation to infinite dilution (EID) method does not sufficiently exclude dimerization and oligomerization effects and therefore could not guarantee total absence of dimers account in the final SAS curve. In this study, we show that EID SAXS, EID SANS and SEC-SAXS methods give complementary results and when they are used all together, it allows obtaining the most accurate results and high confidence from SAS data analysis of proteins.

An implementation of SAS reg-sign in an environmental information system

International Nuclear Information System (INIS)

James, T.; Zygmunt, B.C.

1994-01-01

This paper describes a software environmental database information system that uses SAS to process data and ORACLE reg-sign as the relational database management system (RDBMS). The hardware includes a network of UNIX-based servers and workstations. The relational database consists of large tables containing envionmental measurement data, as well as other smaller tables with reference, metadata and internal administrative information. The data come in a variety of formats and must be converted to conform to the system's standards. SAS/ACCESS reg-sign and PROC SQL are used extensively in the data processing

C-C1-04: How to Win Friends and Influence People with the SAS Output Delivery System

OpenAIRE

Tolbert, William

2010-01-01

Background and Aims: Long-time SAS users remember the days when SAS output was embarrassingly ugly. Version 7 saw the introduction of the Output Delivery System (ODS). ODS has matured into a very capable subsystem that gives users powerful reporting options. This presentation will highlight useful features and outline a macro-based system for handling multiple ODS destinations simultaneously. Nowadays there is no excuse for ugly SAS output! When building reports, SAS users should think about ...

Social Anxiety Scale for Adolescents (SAS-A): Measuring Social Anxiety among Finnish Adolescents

Science.gov (United States)

Ranta, Klaus; Junttila, Niina; Laakkonen, Eero; Uhmavaara, Anni; La Greca, Annette M.; Niemi, Paivi M.

2012-01-01

The aim of this study was to investigate symptoms of social anxiety and the psychometric properties of the "Social Anxiety Scale for Adolescents" (SAS-A) among Finnish adolescents, 13-16 years of age. Study 1 (n = 867) examined the distribution of SAS-A scores according to gender and age, and the internal consistency and factor structure…

SPSS and SAS programming for the testing of mediation models.

Science.gov (United States)

Dudley, William N; Benuzillo, Jose G; Carrico, Mineh S

2004-01-01

Mediation modeling can explain the nature of the relation among three or more variables. In addition, it can be used to show how a variable mediates the relation between levels of intervention and outcome. The Sobel test, developed in 1990, provides a statistical method for determining the influence of a mediator on an intervention or outcome. Although interactive Web-based and stand-alone methods exist for computing the Sobel test, SPSS and SAS programs that automatically run the required regression analyses and computations increase the accessibility of mediation modeling to nursing researchers. To illustrate the utility of the Sobel test and to make this programming available to the Nursing Research audience in both SAS and SPSS. The history, logic, and technical aspects of mediation testing are introduced. The syntax files sobel.sps and sobel.sas, created to automate the computation of the regression analysis and test statistic, are available from the corresponding author. The reported programming allows the user to complete mediation testing with the user's own data in a single-step fashion. A technical manual included with the programming provides instruction on program use and interpretation of the output. Mediation modeling is a useful tool for describing the relation between three or more variables. Programming and manuals for using this model are made available.

Simple and flexible SAS and SPSS programs for analyzing lag-sequential categorical data.

Science.gov (United States)

O'Connor, B P

1999-11-01

This paper describes simple and flexible programs for analyzing lag-sequential categorical data, using SAS and SPSS. The programs read a stream of codes and produce a variety of lag-sequential statistics, including transitional frequencies, expected transitional frequencies, transitional probabilities, adjusted residuals, z values, Yule's Q values, likelihood ratio tests of stationarity across time and homogeneity across groups or segments, transformed kappas for unidirectional dependence, bidirectional dependence, parallel and nonparallel dominance, and significance levels based on both parametric and randomization tests.

Clinical SAS programming in India: A study of industry needs versus wants

Directory of Open Access Journals (Sweden)

Nithiyanandhan Ananthakrishnan

2014-01-01

Full Text Available Background: The clinical SAS (www.sas.com programming industry, in India, has seen a rapid growth in the last decade and the trend seems set to continue, for the next couple of years, due to cost advantage and the availability of skilled labor. On one side the industry needs are focused on less execution time, high margins, segmented tasks and the delivery of high quality output with minimal oversight. On the other side, due to the increased demand for skilled resources, the wants of the programmers have taken a different shift toward diversifying exposure, unsustainable wage inflation due to multiple opportunities and generally high expectations around career progression. If the industry needs are not going to match with programmers want, or vice versa, then there is the possibility that the current year on year growth may start to slow or even go into decline. Aim: This paper is intended to identify the gap between wants and need and puts forwards some suggestions, for both sides, in ways to change the equation to benefit all. Settings and Design: Questionnaire on similar themes created to survey managers and programmers working in clinical SAS programming industry and was surveyed online to collect their perspectives. Their views are compared for each theme and presented as results. Materials and Methods: Two surveys were created in www.surveymonkey.com. Management: https://www.surveymonkey.com/s/SAS_India_managment_needvswant_survey. Programmer: https://www.surveymonkey.com/s/SAS_India_programmer_needvswant_survey. Statistical Analysis Used: Bar chart and pie chart used on data collect to show segmentation of data. Results and Conclusions: In conclusion, it seeks to highlight the future industry direction and the skillset that existing programmers need to have, in order to sustain the momentum and remain competitive, to contribute to the future pipeline and the development of the profession in India.

Clinical SAS programming in India: A study of industry needs versus wants.

Science.gov (United States)

Ananthakrishnan, Nithiyanandhan

2014-07-01

The clinical SAS (www.sas.com) programming industry, in India, has seen a rapid growth in the last decade and the trend seems set to continue, for the next couple of years, due to cost advantage and the availability of skilled labor. On one side the industry needs are focused on less execution time, high margins, segmented tasks and the delivery of high quality output with minimal oversight. On the other side, due to the increased demand for skilled resources, the wants of the programmers have taken a different shift toward diversifying exposure, unsustainable wage inflation due to multiple opportunities and generally high expectations around career progression. If the industry needs are not going to match with programmers want, or vice versa, then there is the possibility that the current year on year growth may start to slow or even go into decline. This paper is intended to identify the gap between wants and need and puts forwards some suggestions, for both sides, in ways to change the equation to benefit all. Questionnaire on similar themes created to survey managers and programmers working in clinical SAS programming industry and was surveyed online to collect their perspectives. Their views are compared for each theme and presented as results. Two surveys were created in www.surveymonkey.com. https://www.surveymonkey.com/s/SAS_India_managment_needvswant_survey. Programmer: https://www.surveymonkey.com/s/SAS_India_programmer_needvswant_survey. Bar chart and pie chart used on data collect to show segmentation of data. In conclusion, it seeks to highlight the future industry direction and the skillset that existing programmers need to have, in order to sustain the momentum and remain competitive, to contribute to the future pipeline and the development of the profession in India.

Centriolar SAS-7 acts upstream of SPD-2 to regulate centriole assembly and pericentriolar material formation

Science.gov (United States)

Sugioka, Kenji; Hamill, Danielle R; Lowry, Joshua B; McNeely, Marie E; Enrick, Molly; Richter, Alyssa C; Kiebler, Lauren E; Priess, James R; Bowerman, Bruce

2017-01-01

The centriole/basal body is a eukaryotic organelle that plays essential roles in cell division and signaling. Among five known core centriole proteins, SPD-2/Cep192 is the first recruited to the site of daughter centriole formation and regulates the centriolar localization of the other components in C. elegans and in humans. However, the molecular basis for SPD-2 centriolar localization remains unknown. Here, we describe a new centriole component, the coiled-coil protein SAS-7, as a regulator of centriole duplication, assembly and elongation. Intriguingly, our genetic data suggest that SAS-7 is required for daughter centrioles to become competent for duplication, and for mother centrioles to maintain this competence. We also show that SAS-7 binds SPD-2 and regulates SPD-2 centriolar recruitment, while SAS-7 centriolar localization is SPD-2-independent. Furthermore, pericentriolar material (PCM) formation is abnormal in sas-7 mutants, and the PCM-dependent induction of cell polarity that defines the anterior-posterior body axis frequently fails. We conclude that SAS-7 functions at the earliest step in centriole duplication yet identified and plays important roles in the orchestration of centriole and PCM assembly. DOI: http://dx.doi.org/10.7554/eLife.20353.001 PMID:28092264

Archive of Census Related Products (ACRP): 1980 SAS Transport Files

Data.gov (United States)

National Aeronautics and Space Administration — The 1980 SAS Transport Files portion of the Archive of Census Related Products (ACRP) contains housing and population demographics from the 1980 Summary Tape File...

%HPGLIMMIX: A High-Performance SAS Macro for GLMM Estimation

Directory of Open Access Journals (Sweden)

Liang Xie

2014-06-01

Full Text Available Generalized linear mixed models (GLMMs comprise a class of widely used statistical tools for data analysis with fixed and random effects when the response variable has a conditional distribution in the exponential family. GLMM analysis also has a close relationship with actuarial credibility theory. While readily available programs such as the GLIMMIX procedure in SAS and the lme4 package in R are powerful tools for using this class of models, these progarms are not able to handle models with thousands of levels of fixed and random effects. By using sparse-matrix and other high performance techniques, procedures such as HPMIXED in SAS can easily fit models with thousands of factor levels, but only for normally distributed response variables. In this paper, we present the %HPGLIMMIX SAS macro that fits GLMMs with large number of sparsely populated design matrices using the doubly-iterative linearization (pseudo-likelihood method, in which the sparse-matrix-based HPMIXED is used for the inner iterations with the pseudo-variable constructed from the inverse-link function and the chosen model. Although the macro does not have the full functionality of the GLIMMIX procedure, time and memory savings can be large with the new macro. In applications in which design matrices contain many zeros and there are hundreds or thousands of factor levels, models can be fitted without exhausting computer memory, and 90% or better reduction in running time can be observed. Examples with a Poisson, binomial, and gamma conditional distribution are presented to demonstrate the usage and efficiency of this macro.

The Development of Student’s Activity Sheets (SAS) Based on Multiple Intelligences and Problem-Solving Skills Using Simple Science Tools

Science.gov (United States)

Wardani, D. S.; Kirana, T.; Ibrahim, M.

2018-01-01

The aim of this research is to produce SAS based on MI and problem-solving skills using simple science tools that are suitable to be used by elementary school students. The feasibility of SAS is evaluated based on its validity, practicality, and effectiveness. The completion Lesson Plan (LP) implementation and student’s activities are the indicators of SAS practicality. The effectiveness of SAS is measured by indicators of increased learning outcomes and problem-solving skills. The development of SAS follows the 4-D (define, design, develop, and disseminate) phase. However, this study was done until the third stage (develop). The written SAS was then validated through expert evaluation done by two experts of science, before its is tested to the target students. The try-out of SAS used one group with pre-test and post-test design. The result of this research shows that SAS is valid with “good” category. In addition, SAS is considered practical as seen from the increase of student activity at each meeting and LP implementation. Moreover, it was considered effective due to the significant difference between pre-test and post-test result of the learning outcomes and problem-solving skill test. Therefore, SAS is feasible to be used in learning.

Effect of hyperbaric oxygen therapy on SAS and SDS in children with ischemic encephalopathy

Directory of Open Access Journals (Sweden)

Pei-Yun Li

2017-08-01

Full Text Available Objective: To study and analyze the effect of early psychological intervention on the scores of SAS and SDS in children with hypoxic-ischemic encephalopathy undergoing hyperbaric oxygen therapy. Methods: A total of 64 children with hypoxic - ischemic encephalopathy enrolled in our hospital from July 2015 to July 2016 and their parents were selected as study subjects. The patients were treated with hyperbaric oxygen therapy, while their parents were given early psychological intervention. By the way of increasing parents’ awareness of the disease, helping parents build confidence in their children’s treatment and encouraging them to participate in daily training for their children to relieve their anxiety and depression. The parents' knowledge of the disease before and during treatment, the treatment of hyperbaric oxygen therapy and the change of SAS and SDS were observed. Results: After effective intervention, the scores of SAS and SDS of 64 patients’ parents were significantly lower than those before treatment. After 1 courses of intervention, the score of SAS was (43.36 ± 1.27 points, and the score of SDS was (45.22 ± 8.13 points. After 2 courses of intervention, the score of SAS was (41.07 ± 1.21 and the score of SDS was (42.35 ± 7.44 points, and parents' awareness of hypoxic-ischemic encephalopathy was significantly increased, and the differences between the two groups were statistically significant. Conclusion: Early psychological intervention on parents of children with hypoxic-ischemic encephalopathy can effectively improve the awareness of parents on the disease, so as to improve their acceptance of hyperbaric oxygen therapy; significantly reduce the parents’ SAS, SDS score. It is beneficial to build a good doctor-patient and nurse-patient relationship, improve the treatment effect and shorten the treatment time.

Design and analysis of experiments with SAS

CERN Document Server

Lawson, John

2010-01-01

IntroductionStatistics and Data Collection Beginnings of Statistically Planned Experiments Definitions and Preliminaries Purposes of Experimental Design Types of Experimental Designs Planning Experiments Performing the Experiments Use of SAS SoftwareCompletely Randomized Designs with One Factor Introduction Replication and Randomization A Historical Example Linear Model for Completely Randomized Design (CRD) Verifying Assumptions of the Linear Model Analysis Strategies When Assumptions Are Violated Determining the Number of Replicates Comparison of Treatments after the F-TestFactorial Designs

An alternative to the SAS2H/ORIGEN-S sequence to account for water-density effects in BWR systems

International Nuclear Information System (INIS)

Leal, L.C.; Hermann, O.W.; Ryman, J.C.; Broadhead, B.L.

1996-01-01

A scheme to generate one-group problem-dependent cross-section libraries for point-depletion calculations with the ORIGEN-S code was developed as an alternative to the SAS2H sequence of the SCALE code system. The methodology, named Automatic Rapid Processing (ARP), generates libraries by interpolating in SAS2H precomputed cross section libraries. The method has been used to generate ORIGEN-S cross section libraries on a personal computer resulting in a great reduction of computer time without a sacrifice of accuracy over that required by corresponding SAS2H calculations. The ARP scheme generates ORIGEN-S libraries by interpolating in burnup and enrichment for PWR assemblies. The intent of this work is to describe a procedure which extends the application of the ARP methodology to BWR assemblies by including the axial water-density effects in the generation of the ORIGEN-S cross-section libraries. The axial liquid- to-steam change of state in BWR systems leads to a variation in the water density and significant cross-section changes as a function of the water density. To account for the axial water-density changes in a SAS2H calculation, the water density is entered explicitly in the generation of the one-group ORIGEN-S cross-section libraries generated from the SCALE 27-group library. In its original version, ARP does not account for the effects of water-density variation in ORIGEN-S cross-section library generation, and, therefore, its application is restricted to systems for which the impact of this parameter is negligible. To update the ARP methodology to account for the water-density effect, a detailed study of the cross-section change with this parameter was performed with an 8 x 8 (General Electric) BWR assembly

Unsteady Simulations of the Flow in a Channel Flow and a Ventilated Room Using the SST-SAS Model

DEFF Research Database (Denmark)

Davidson, Lars; Nielsen, Peter V.

The SAS model (Scale Adapted Simulation) was invented by Menter and his co-workers. The idea behind the SST-SAS model is to add an additional production term - the SAS term - in the w equation which is sensitive to resolved (i.e. unsteady) fluctuations. In regions where the flow is on the limit...

PS3-21: Extracting Utilization Data from Clarity into VDW Using Oracle and SAS

Science.gov (United States)

Chimmula, Srivardhan

2013-01-01

Background/Aims The purpose of the presentation is to demonstrate how we use SAS and Oracle to load VDW_Utilization, VDW_DX, and VDW_PX tables from Clarity at the Kaiser Permanente Northern California (KPNC) Division of Research (DOR) site. Methods DOR uses the best of Oracle PL/ SQL and SAS capabilities in building Extract Transform and Load (ETL) processes. These processes extract patient encounter, diagnosis, and procedure data from Teradata-based Clarity. The data is then transformed to fit HMORN’s VDW definitions of the table. This data is then loaded into the Oracle-based VDW table on DOR’s research database and then finally a copy of the table is also created as a SAS dataset. Results DOR builds robust and efficient ETL processes that refresh VDW Utilization table on a monthly basis processing millions of records/observations. The ETL processes have the capability to identify daily changes in Clarity and update the VDW tables on a daily basis. Conclusions KPNC DOR combines the best of both Oracle and SAS worlds to build ETL processes that load the data into VDW Utilization tables efficiently.

A SAS-macro for estimation of the cumulative incidence using Poisson regression

DEFF Research Database (Denmark)

Waltoft, Berit Lindum

2009-01-01

the hazard rates, and the hazard rates are often estimated by the Cox regression. This procedure may not be suitable for large studies due to limited computer resources. Instead one uses Poisson regression, which approximates the Cox regression. Rosthøj et al. presented a SAS-macro for the estimation...... of the cumulative incidences based on the Cox regression. I present the functional form of the probabilities and variances when using piecewise constant hazard rates and a SAS-macro for the estimation using Poisson regression. The use of the macro is demonstrated through examples and compared to the macro presented...

SEPARATION ANXIETY SYNDROME (SAS IN DOGS FROM FERNANDOPOLIS, SP, REFERRED TO UNICASTELO VETERINARY HOSPITAL SÍNDROME DA ANSIEDADE DE SEPARAÇÃO (SAS EM CÃES ATENDIDOS NO HOSPITAL VETERINÁRIO DA UNICASTELO, FERNANDÓPOLIS, SP

Directory of Open Access Journals (Sweden)

Adriana Alonso Novais

2010-04-01

Full Text Available The separation anxiety syndrome (SAS is defined by a group of altered behaviors showed by dogs when they are left alone, contributing for the most common behavior problems in this specie. The basic clinical signs of SAS are the following: distress vocalization (whining, barking, howling, destructiveness and house soiling. SAS reduce the animal’s life quality and is a frequent cause of abandonment and euthanasia of these dogs. The goal of this research was to verify the occurrence of SAS in dogs from Fernandopolis, SP, referred to the veterinary hospital of Unicastelo, in the period lying between december/2007 and december/2008. Seventy five animals were studied, comprising 30 (40% adult males, 9 (12% young males, 30 (40% adult females and 6 (8% young females. The dogs were evaluated through data given by the owners, according to a behavior questionnaire. From the general studied population, 35 dogs (47% showed distress vocalization, 29 (39% dogs showed micturition at inappropriate places, 17 (23% dogs showed defecation at inappropriate places and 22 (29% showed destructiveness during the periods of the owner’s absence. From the obtained results we may conclude the occurrence of SAS in 68% of the studied dogs.

KEY WORDS: Dogs, animal behavior, behavior disturbances, SAS.

A síndrome da ansiedade de separação (SAS é definida como o conjunto de comportamentos exibidos por cães quando são deixados sozinhos. É considerada um dos problemas comportamentais mais comuns da espécie. Os sinais clínicos básicos da SAS são vocalização excessiva, destruição de objetos, defecação e micção em locais impróprios, acarretando prejuízos na qualidade de vida dos animais. Sendo uma das causas de abandono e eutanásia desses animais, a SAS foi pesquisada em cães atendidos no Hospital Veterinário da Unicastelo em Fernandópolis, SP, no período de dezembro de 2007 a dezembro de 2008, mediante levantamento realizado em 75

Relap4/SAS/Mod5 - A version of Relap4/Mod 5 adapted to IPEN/CNEN - SP computer center

International Nuclear Information System (INIS)

Sabundjian, G.

1988-04-01

In order to improve the safety of nuclear reactor power plants several computer codes have been developed in the area of thermal - hydraulics accident analysis. Among the public-available codes, RELAP4, developed by Aerojet Nuclear Company, has been the most popular one. RELAP4 has produced satisfactory results when compared to most of the available experimental data. The purposes of the present work are: optimization of RELAP4 output and messages by writing there information in temporary records, - display of RELAP4 results in graphical form through the printer. The sample problem consists on a simplified model of a 150 MW (e) PWR whose primary circuit is simulated by 6 volumes, 8 junctions and 1 heat slab. This new version of RELAP4 (named RELAP4/SAS/MOD5) have produced results which show that the above mentioned purposes have been reached. Obviously the graphical output by RELAP4/SAS/MOD5 favors the interpretation of results by the user. (author) [pt

Using SAS PROC MCMC for Item Response Theory Models

Science.gov (United States)

Ames, Allison J.; Samonte, Kelli

2015-01-01

Interest in using Bayesian methods for estimating item response theory models has grown at a remarkable rate in recent years. This attentiveness to Bayesian estimation has also inspired a growth in available software such as WinBUGS, R packages, BMIRT, MPLUS, and SAS PROC MCMC. This article intends to provide an accessible overview of Bayesian…

SAS4A and FPIN2X validation for slow ramp TOP accidents: experiments TS-1 and TS-2

International Nuclear Information System (INIS)

Hill, D.J.

1986-01-01

The purpose of this paper is to present further results in the series of experimental analyses being performed using SAS4A and FPIN2X in order to provide a systematic validation of these codes. The two experiments discussed here, TS-1 and TS-2, were performed by Westinghouse Hanford/Hanford Engineering Development Laboratory (WHC/HEDL) in the Transient Reactor Test (TREAT) Facility. They were slow ramp transient overpowers (TOPs) of ∼ 5 cent/s equivalent Fast Flux Test Facility (FFTF) ramp rate, single-pin experiments in flowing sodium loops. The good agreement found here adds significantly to the experimental data base that provides the foundation for SAS4A and FPIN2X validation. It also shows that prefailure internal fuel motion is a phenomenon that has to be correctly accounted for, not only as a potential inherent safety mechanism, but also before any accurate prediction of fuel failure and subsequent fuel motion and the associated reactivity effects can be made. This is also true for metal-fueled pins. This capability is provided by PINACLE, which is being incorporated into SAS4A

Modeling binary correlated responses using SAS, SPSS and R

CERN Document Server

Wilson, Jeffrey R

2015-01-01

Statistical tools to analyze correlated binary data are spread out in the existing literature. This book makes these tools accessible to practitioners in a single volume. Chapters cover recently developed statistical tools and statistical packages that are tailored to analyzing correlated binary data. The authors showcase both traditional and new methods for application to health-related research. Data and computer programs will be publicly available in order for readers to replicate model development, but learning a new statistical language is not necessary with this book. The inclusion of code for R, SAS, and SPSS allows for easy implementation by readers. For readers interested in learning more about the languages, though, there are short tutorials in the appendix. Accompanying data sets are available for download through the book s website. Data analysis presented in each chapter will provide step-by-step instructions so these new methods can be readily applied to projects.  Researchers and graduate stu...

The Spectrum Analysis Solution (SAS) System: Theoretical Analysis, Hardware Design and Implementation.

Science.gov (United States)

Narayanan, Ram M; Pooler, Richard K; Martone, Anthony F; Gallagher, Kyle A; Sherbondy, Kelly D

2018-02-22

This paper describes a multichannel super-heterodyne signal analyzer, called the Spectrum Analysis Solution (SAS), which performs multi-purpose spectrum sensing to support spectrally adaptive and cognitive radar applications. The SAS operates from ultrahigh frequency (UHF) to the S-band and features a wideband channel with eight narrowband channels. The wideband channel acts as a monitoring channel that can be used to tune the instantaneous band of the narrowband channels to areas of interest in the spectrum. The data collected from the SAS has been utilized to develop spectrum sensing algorithms for the budding field of spectrum sharing (SS) radar. Bandwidth (BW), average total power, percent occupancy (PO), signal-to-interference-plus-noise ratio (SINR), and power spectral entropy (PSE) have been examined as metrics for the characterization of the spectrum. These metrics are utilized to determine a contiguous optimal sub-band (OSB) for a SS radar transmission in a given spectrum for different modalities. Three OSB algorithms are presented and evaluated: the spectrum sensing multi objective (SS-MO), the spectrum sensing with brute force PSE (SS-BFE), and the spectrum sensing multi-objective with brute force PSE (SS-MO-BFE).

SAS3A analysis of natural convection boiling behavior in the Sodium Boiling Test Facility

International Nuclear Information System (INIS)

Klein, G.A.

1979-01-01

An analysis of natural convection boiling behavior in the Sodium Boiling Test (SBT) Facility has been performed using the SAS3A computer code. The predictions from this analysis indicate that stable boiling can be achieved for extensive periods of time for channel powers less than 1.4 kW and indicate intermittent dryout at higher powers up to at least 1.7 kW. The results of this anaysis are in reasonable agreement with the SBT Facility test results

Comparison of the SASSYS/SAS4A radial core expansion reactivity feedback model and the empirical correlation for FFTF

International Nuclear Information System (INIS)

Wigeland, R.A.

1987-01-01

The present emphasis on inherent safety for LMR designs has resulted in a need to represent the various reactivity feedback mechanisms as accurately as possible. The dominant negative reactivity feedback has been found to result from radial expansion of the core for most postulated ATWS events. For this reason, a more detailed model for calculating the reactivity feedback from radial core expansion has been recently developed for use with the SASSYS/SAS4A Code System. The purpose of this summary is to present an extension to the model so that it is more suitable for handling a core restraint design as used in FFTF, and to compare the SASSYS/SAS4A results using this model to the empirical correlation presently being used to account for radial core expansion reactivity feedback to FFTF

SAS6-like protein in Plasmodium indicates that conoid-associated apical complex proteins persist in invasive stages within the mosquito vector.

Science.gov (United States)

Wall, Richard J; Roques, Magali; Katris, Nicholas J; Koreny, Ludek; Stanway, Rebecca R; Brady, Declan; Waller, Ross F; Tewari, Rita

2016-06-24

The SAS6-like (SAS6L) protein, a truncated paralogue of the ubiquitous basal body/centriole protein SAS6, has been characterised recently as a flagellum protein in trypanosomatids, but associated with the conoid in apicomplexan Toxoplasma. The conoid has been suggested to derive from flagella parts, but is thought to have been lost from some apicomplexans including the malaria-causing genus Plasmodium. Presence of SAS6L in Plasmodium, therefore, suggested a possible role in flagella assembly in male gametes, the only flagellated stage. Here, we have studied the expression and role of SAS6L throughout the Plasmodium life cycle using the rodent malaria model P. berghei. Contrary to a hypothesised role in flagella, SAS6L was absent during gamete flagellum formation. Instead, SAS6L was restricted to the apical complex in ookinetes and sporozoites, the extracellular invasive stages that develop within the mosquito vector. In these stages SAS6L forms an apical ring, as we show is also the case in Toxoplasma tachyzoites. The SAS6L ring was not apparent in blood-stage invasive merozoites, indicating that the apical complex is differentiated between the different invasive forms. Overall this study indicates that a conoid-associated apical complex protein and ring structure is persistent in Plasmodium in a stage-specific manner.

Síndrome de apnea del sueño (SAS Sleep apnea syndrome

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Camilo José Borrego Abello

1994-03-01

Full Text Available Se describe el síndrome de apnea del sueño (SAS abarcando los aspectos históricos, signos y síntomas, las diversas modalidades (apneas obstructiva, central y mixta, complicaciones, principalmente cardiovasculares y cerebrovasculares y formas de tratamiento. Se hace énfasis en la ayuda diagnóstica del polisomnograma que ha permitido definir como SAS síntomas antes considerados inespecíficos y cuantificar su gravedad. Se describen las diversas medidas terapéuticas, locales y generales, recalcando los beneficios que se obtienen con la aplicación de los aparatos de respiración a presión positiva. Estos permiten tratamientos no invasivos que hacen desaparecer la totalidad de los síntomas y evitan los riesgos incrementados de trastornos cardiovasculares y accidentes laborales o de tránsito. Este grave síndrome afecta a un grupo grande de población por lo que su importancia es indudable.

Different aspects of the sleep apnea síndrome (SAS are described, including history, clinical manifestations, clinical forms (obstructive, central and mixed, cardiovascular, cerebrovascular and other complications and treatment. With the use of the polysomnogram it has been possible to define non-specific symptoms as due to SAS and to quantitate their seriousness. Different therapeutic approaches are described, both local and systemic, with emphasis on the benefits obtained from the use of positive pressure breathing machines which control every manifestation of the syndrome and avoid the increased cardiovascular risks aswell as work and traffic accidents. This syndrome is important in terms of frequency and of increased death risk.

De novo centriole formation in human cells is error-prone and does not require SAS-6 self-assembly.

Science.gov (United States)

Wang, Won-Jing; Acehan, Devrim; Kao, Chien-Han; Jane, Wann-Neng; Uryu, Kunihiro; Tsou, Meng-Fu Bryan

2015-11-26

Vertebrate centrioles normally propagate through duplication, but in the absence of preexisting centrioles, de novo synthesis can occur. Consistently, centriole formation is thought to strictly rely on self-assembly, involving self-oligomerization of the centriolar protein SAS-6. Here, through reconstitution of de novo synthesis in human cells, we surprisingly found that normal looking centrioles capable of duplication and ciliation can arise in the absence of SAS-6 self-oligomerization. Moreover, whereas canonically duplicated centrioles always form correctly, de novo centrioles are prone to structural errors, even in the presence of SAS-6 self-oligomerization. These results indicate that centriole biogenesis does not strictly depend on SAS-6 self-assembly, and may require preexisting centrioles to ensure structural accuracy, fundamentally deviating from the current paradigm.

PREFACE Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

Science.gov (United States)

King, Stephen; Terrill, Nicholas

2010-10-01

The XIV International Conference on Small-Angle Scattering, SAS-2009, was held in Oxford UK, 13-18 September 2009, and was jointly organised under the auspices of the International Union of Crystallography Commission on SAS by a team from the Diamond Light Source and the ISIS Pulsed Neutron Source - their first such joint venture - with help from the UK Science and Technology Facilities Council. It was the first time that this long running and successful series of conferences on the application, science and technology of small-angle scattering techniques had been staged in the UK. The UK has a proud heritage in small-angle scattering: as home to one of the world's first SANS instruments (at AERE Harwell), as the site of the world's first 2nd generation X-ray Synchrotron (the SRS at Daresbury with its suite of SAXS beamlines), and latterly as the location of the world's most successful pulsed source SANS instrument. Indeed, 2009 also marked the 25th Anniversary of neutron operations at ISIS and the opening of a Second Target Station. Whilst the SRS ceased operations in 2008, its mantle has been inherited by the Diamond synchrotron. Many delegates took the opportunity to visit both Diamond and ISIS during a conference excursion. Despite the prevailing global economic downturn, we were delighted that 434 delegates from 32 different countries were able to attend SAS-2009; two-thirds were drawn from the UK, Germany, Japan, the USA and France, but there were also sizeable contingents from Australia, Korea, Taiwan and South America. In many ways this geographical spread reflects the present and emerging distribution, respectively, of 3rd generation X-ray synchrotrons and high-flux neutron sources, although the scope of the conference was not solely limited to these probes. Financial support from the IUCr enabled us to grant bursaries to attend SAS-2009 to 12 delegates from emerging countries (Algeria, Argentina, Brazil, India, Nepal, Romania, Russia and the Ukraine). The

Repositioning the substrate activity screening (SAS) approach as a fragment-based method for identification of weak binders.

Science.gov (United States)

Gladysz, Rafaela; Cleenewerck, Matthias; Joossens, Jurgen; Lambeir, Anne-Marie; Augustyns, Koen; Van der Veken, Pieter

2014-10-13

Fragment-based drug discovery (FBDD) has evolved into an established approach for "hit" identification. Typically, most applications of FBDD depend on specialised cost- and time-intensive biophysical techniques. The substrate activity screening (SAS) approach has been proposed as a relatively cheap and straightforward alternative for identification of fragments for enzyme inhibitors. We have investigated SAS for the discovery of inhibitors of oncology target urokinase (uPA). Although our results support the key hypotheses of SAS, we also encountered a number of unreported limitations. In response, we propose an efficient modified methodology: "MSAS" (modified substrate activity screening). MSAS circumvents the limitations of SAS and broadens its scope by providing additional fragments and more coherent SAR data. As well as presenting and validating MSAS, this study expands existing SAR knowledge for the S1 pocket of uPA and reports new reversible and irreversible uPA inhibitor scaffolds. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Embedding SAS approach into conjugate gradient algorithms for asymmetric 3D elasticity problems

Energy Technology Data Exchange (ETDEWEB)

Chen, Hsin-Chu; Warsi, N.A. [Clark Atlanta Univ., GA (United States); Sameh, A. [Univ. of Minnesota, Minneapolis, MN (United States)

1996-12-31

In this paper, we present two strategies to embed the SAS (symmetric-and-antisymmetric) scheme into conjugate gradient (CG) algorithms to make solving 3D elasticity problems, with or without global reflexive symmetry, more efficient. The SAS approach is physically a domain decomposition scheme that takes advantage of reflexive symmetry of discretized physical problems, and algebraically a matrix transformation method that exploits special reflexivity properties of the matrix resulting from discretization. In addition to offering large-grain parallelism, which is valuable in a multiprocessing environment, the SAS scheme also has the potential for reducing arithmetic operations in the numerical solution of a reasonably wide class of scientific and engineering problems. This approach can be applied directly to problems that have global reflexive symmetry, yielding smaller and independent subproblems to solve, or indirectly to problems with partial symmetry, resulting in loosely coupled subproblems. The decomposition is achieved by separating the reflexive subspace from the antireflexive one, possessed by a special class of matrices A, A {element_of} C{sup n x n} that satisfy the relation A = PAP where P is a reflection matrix (symmetric signed permutation matrix).

Agent Based Model in SAS Environment for Rail Transit System Alignment Determination

Directory of Open Access Journals (Sweden)

I Made Indradjaja Brunner

2018-04-01

Full Text Available Transit system had been proposed for the urban area of Honolulu. One consideration to be determined is the alignment of the transit system. Decision to set the transit alignment will have influences on which areas will be served, who will be benefiting, as well as who will be impacted. Inputs for the decision usually conducted through public meetings, where community members are shown numbers of maps with pre-set routes. That approach could lead to a rather subjective decision by the community members. This paper attempts to discuss the utilization of grid map in determining the best alignment for rail transit system in Honolulu, Hawaii. It tries to use a more objective approach using various data derived from thematic maps. Overlaid maps are aggregated into a uniform 0.1-square mile vector based grid map system in GIS environment. The large dataset in the GIS environment is analyzed and manipulated using SAS software. The SAS procedure is applied to select the location of the alignment using a rational and deterministic approach. Grid cells that are superior compared to the others are selected based on several predefined criteria. Location of the dominant cells indicates possible transit alignment. The SAS procedure is designed to allow a transient vector called the GUIDE (Grid Unit with Intelligent Directional Expertise agent to analyze several cells at its vicinity and to move towards a cell with the highest value. Each time the agent landed on a cell, it left a mark. The chain of those marks shows location for the transit alignment. This study shows that the combination of ArcGIS and SAS allows a robust analysis of spatial data and manipulation of its datasets, which can be used to run a simulation mimicking the Agent-Based Modelling. This study also opens up further study possibilities by increasing number of factors analyzed by the agent, as well as creating a composite value of multi-factors.

Escala de sociotropía-autonomía (SAS: propiedades psicométricas de la adaptación a Colombia

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Ronald Alberto Toro Tobar

2014-07-01

Full Text Available Este artículo presenta los resultados de una investigación cuyo objetivo fue adaptar y validar la Escala de Sociotropía-Autonomía (SAS de Clark & Beck, la cual evalúa dos dimensiones de personalidad cognitiva: la orientación interpersonal y actitudes de logro y metas personales. La muestra consistió en 460 participantes entre 15 y 71 años, escolarizados de distintos estratos socioeconómicos. Los resultados mostraron índices de consistencia interna en la Escala SAS: total (,85, SAS Sociotropía (,82 y menores para SAS autonomía (,61. Estos resultados guardan relación con investigaciones acerca de este instrumento; por lo tanto se considera confiable y válido para el contexto sociocultural; además podría apoyar la investigación en psicoterapia cognitiva y en procesos clínicos basados en el modelo diátesis estrés. Abstract This paper presents the results of a study whose aim was adapt and validate the Sociotropy-Autonomy Scale (SAS Clark & Beck. This scale assesses two dimensions of cognitive personality: interpersonal orientation and attitudes of achievement and personal goals. The sample consisted of 460 participants between 15 and 71 years enrolled from different socioeconomic levels. The results showed internal consistency in SAS Scale: Total (.85, SAS Sociotropy (.82 and lower for SAS Autonomy (.61. These results are relevant to research on this instrument. It is considered a reliable and valid instrument for socio-cultural context; could also support research in cognitive psychotherapy and clinical processes based on the diathesis stress model.

Confirmatory factor analysis and sample invariance of the Chinese version of Somatosensory Amplification Scale (ChSAS) among Chinese adolescents

OpenAIRE

Tam, B. K.; Wong, W. S.

2011-01-01

Objective: This paper aimed to evaluate the factor structure of the Chinese version of Somatosensory Amplification Scale (ChSAS) in a sample of Chinese adolescents across different grade levels using confirmatory factor analysis (CFA). Methods: A total of 1991 Chinese adolescents completed the ChSAS. CFA assessed the fit of the one-factor model to the entire sample. Factorial invariance of the ChSAS was also examined across grade levels using multigroup CFA. Results: Results of CFA confirmed ...

The School Anxiety Scale-Teacher Report (SAS-TR): translation and psychometric properties of the Iranian version.

Science.gov (United States)

Hajiamini, Zahra; Mohamadi, Ashraf; Ebadi, Abbas; Fathi- Ashtiani, Ali; Tavousi, Mahmoud; Montazeri, Ali

2012-07-18

The School Anxiety Scale-Teacher Report (SAS-TR) was designed to assess anxiety in children at school. The SAS-TR is a proxy rated measure and could assess social anxiety, generalized anxiety and also gives a total anxiety score. This study aimed to translate and validate the SAS-TR in Iran. The translation and cultural adaptation of the original questionnaire were carried out in accordance with the published guidelines. A sample of students participated in the study. Reliability was estimated using internal consistency and test-retest analysis. Validity was assessed using content validity. The factor structure of the questionnaire was extracted by performing both exploratory and confirmatory factor analyses. In all 200 elementary students aged 6 to 10 years were studied. Considering the recommended cut-off values, overall the prevalence of high anxiety condition in elementary students was found to be 21 %. Cronbach's alpha coefficient for the Iranian SAS-TR was 0.92 and intraclass correlation coefficient (ICC) was found to be 0.81. The principal component analysis indicated a two-factor structure for the questionnaire (generalized and social anxiety) that jointly accounted for 55.3 % of variances observed. The confirmatory factory analysis also indicated a good fit to the data for the two-latent structure of the questionnaire. In general the findings suggest that the Iranian version of SAS-TR has satisfactory reliability, and validity for measuring anxiety in 6 to 10 years old children in Iran. It is simple and easy to use and now can be applied in future studies.

Cosmic radiation and airline pilots. Exposure patterns of Norwegian SAS-pilots 1960 to 1994

International Nuclear Information System (INIS)

Tveten, U.

1997-02-01

The work which is presented in this report is part of a Norwegian epidemiological project, carried out in cooperation between Institutt for Energiteknikk (IFE), the Norwegian Cancer Registry (NCR) and the Norwegian Radiation Protection Authority (NRPA). The project has been partially financed by the Norwegian Research Council. Originating from the Norwegian project, a number of similar projects have been started or are in the planning stage in a number of European countries. The present report lays the ground for estimation of individual exposure histories to cosmic radiation of pilots employed by the Scandinavian Airline System (SAS). The results presented in this report (radiation doserates for the different types of aircraft in the different years) will, in a later stage of the project, be utilized to estimate the individual radiation exposure histories. The major sources of information used as basis for this work is the collection of old SAS time tables found in the SAS Museum at Fornebu Airport in Oslo, and information provided by members of the Pilots Associations

Cosmic radiation and airline pilots. Exposure patterns of Norwegian SAS-pilots 1960 to 1994

Energy Technology Data Exchange (ETDEWEB)

Tveten, U.

1997-02-01

The work which is presented in this report is part of a Norwegian epidemiological project, carried out in cooperation between Institutt for Energiteknikk (IFE), the Norwegian Cancer Registry (NCR) and the Norwegian Radiation Protection Authority (NRPA). The project has been partially financed by the Norwegian Research Council. Originating from the Norwegian project, a number of similar projects have been started or are in the planning stage in a number of European countries. The present report lays the ground for estimation of individual exposure histories to cosmic radiation of pilots employed by the Scandinavian Airline System (SAS). The results presented in this report (radiation doserates for the different types of aircraft in the different years) will, in a later stage of the project, be utilized to estimate the individual radiation exposure histories. The major sources of information used as basis for this work is the collection of old SAS time tables found in the SAS Museum at Fornebu Airport in Oslo, and information provided by members of the Pilots Associations.

SAS2: Guide sur la recherche collaborative et l'engagement social

International Development Research Centre (IDRC) Digital Library (Canada)

À l'encontre de cette façon de voir, les SAS2 favorisent l'« ancrage social » et la ..... les organismes communautaires, les médias, les fondations philanthropiques, ...... Portez attention aux différences qui peuvent influencer la manière dont les ...

Propiedades psicom??tricas de la versi??n espa??ola de la Sexual Assertiveness Scale (SAS)

OpenAIRE

Sierra Freire, Juan Carlos; Vallejo-Medina, Pablo; Santos-Iglesias, Pablo

2011-01-01

La asertividad sexual se refiere a la capacidad de las personas para iniciar la actividad sexual, rechazar la actividad sexual no deseada y emplear m??todos anticonceptivos, desarrollando comportamientos saluda- bles. La Sexual Assertiveness Scale (SAS) es una escala de 18 ??tems que eval??a tres dimensiones: Inicio, Rechazo y Prevenci??n Embarazo-ETS (E-ETS). En este estudio 853 personas contestaron la SAS, junto a una bater??a de ins- trumentos afines. La puntuaci??n media de los ??tems ha ...

Genome sequencing and annotation of Proteus sp. SAS71

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Samy Selim

2015-12-01

Full Text Available We report draft genome sequence of Proteus sp. strain SAS71, isolated from water spring in Aljouf region, Saudi Arabia. The draft genome size is 3,037,704 bp with a G + C content of 39.3% and contains 6 rRNA sequence (single copies of 5S, 16S & 23S rRNA. The genome sequence can be accessed at DDBJ/EMBL/GenBank under the accession no. LDIU00000000.

The School Anxiety Scale-Teacher Report (SAS-TR: translation and psychometric properties of the Iranian version

Directory of Open Access Journals (Sweden)

Hajiamini Zahra

2012-07-01

Full Text Available Abstract Background The School Anxiety Scale-Teacher Report (SAS-TR was designed to assess anxiety in children at school. The SAS-TR is a proxy rated measure and could assess social anxiety, generalized anxiety and also gives a total anxiety score. This study aimed to translate and validate the SAS-TR in Iran. Methods The translation and cultural adaptation of the original questionnaire were carried out in accordance with the published guidelines. A sample of students participated in the study. Reliability was estimated using internal consistency and test-retest analysis. Validity was assessed using content validity. The factor structure of the questionnaire was extracted by performing both exploratory and confirmatory factor analyses. Results In all 200 elementary students aged 6 to 10 years were studied. Considering the recommended cut-off values, overall the prevalence of high anxiety condition in elementary students was found to be 21 %. Cronbach's alpha coefficient for the Iranian SAS-TR was 0.92 and intraclass correlation coefficient (ICC was found to be 0.81. The principal component analysis indicated a two-factor structure for the questionnaire (generalized and social anxiety that jointly accounted for 55.3 % of variances observed. The confirmatory factory analysis also indicated a good fit to the data for the two-latent structure of the questionnaire. Conclusion In general the findings suggest that the Iranian version of SAS-TR has satisfactory reliability, and validity for measuring anxiety in 6 to 10 years old children in Iran. It is simple and easy to use and now can be applied in future studies.

Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS).

Science.gov (United States)

Perkins, Stephen J; Wright, David W; Zhang, Hailiang; Brookes, Emre H; Chen, Jianhan; Irving, Thomas C; Krueger, Susan; Barlow, David J; Edler, Karen J; Scott, David J; Terrill, Nicholas J; King, Stephen M; Butler, Paul D; Curtis, Joseph E

2016-12-01

The capabilities of current computer simulations provide a unique opportunity to model small-angle scattering (SAS) data at the atomistic level, and to include other structural constraints ranging from molecular and atomistic energetics to crystallography, electron microscopy and NMR. This extends the capabilities of solution scattering and provides deeper insights into the physics and chemistry of the systems studied. Realizing this potential, however, requires integrating the experimental data with a new generation of modelling software. To achieve this, the CCP-SAS collaboration (http://www.ccpsas.org/) is developing open-source, high-throughput and user-friendly software for the atomistic and coarse-grained molecular modelling of scattering data. Robust state-of-the-art molecular simulation engines and molecular dynamics and Monte Carlo force fields provide constraints to the solution structure inferred from the small-angle scattering data, which incorporates the known physical chemistry of the system. The implementation of this software suite involves a tiered approach in which GenApp provides the deployment infrastructure for running applications on both standard and high-performance computing hardware, and SASSIE provides a workflow framework into which modules can be plugged to prepare structures, carry out simulations, calculate theoretical scattering data and compare results with experimental data. GenApp produces the accessible web-based front end termed SASSIE-web , and GenApp and SASSIE also make community SAS codes available. Applications are illustrated by case studies: (i) inter-domain flexibility in two- to six-domain proteins as exemplified by HIV-1 Gag, MASP and ubiquitin; (ii) the hinge conformation in human IgG2 and IgA1 antibodies; (iii) the complex formed between a hexameric protein Hfq and mRNA; and (iv) synthetic 'bottlebrush' polymers.

Quality assurance management plan (QAPP) special analytical support (SAS)

Energy Technology Data Exchange (ETDEWEB)

LOCKREM, L.L.

1999-05-20

It is the policy of Special Analytical Support (SAS) that the analytical aspects of all environmental data generated and processed in the laboratory, subject to the Environmental Protection Agency (EPA), U.S. Department of Energy or other project specific requirements, be of known and acceptable quality. It is the intention of this QAPP to establish and assure that an effective quality controlled management system is maintained in order to meet the quality requirements of the intended use(s) of the data.

Quality assurance management plan (QAPP) special analytical support (SAS)

International Nuclear Information System (INIS)

LOCKREM, L.L.

1999-01-01

It is the policy of Special Analytical Support (SAS) that the analytical aspects of all environmental data generated and processed in the laboratory, subject to the Environmental Protection Agency (EPA), U.S. Department of Energy or other project specific requirements, be of known and acceptable quality. It is the intention of this QAPP to establish and assure that an effective quality controlled management system is maintained in order to meet the quality requirements of the intended use(s) of the data

Comparison of ArcGIS and SAS Geostatistical Analyst to Estimate Population-Weighted Monthly Temperature for US Counties.

Science.gov (United States)

Xiaopeng, Q I; Liang, Wei; Barker, Laurie; Lekiachvili, Akaki; Xingyou, Zhang

Temperature changes are known to have significant impacts on human health. Accurate estimates of population-weighted average monthly air temperature for US counties are needed to evaluate temperature's association with health behaviours and disease, which are sampled or reported at the county level and measured on a monthly-or 30-day-basis. Most reported temperature estimates were calculated using ArcGIS, relatively few used SAS. We compared the performance of geostatistical models to estimate population-weighted average temperature in each month for counties in 48 states using ArcGIS v9.3 and SAS v 9.2 on a CITGO platform. Monthly average temperature for Jan-Dec 2007 and elevation from 5435 weather stations were used to estimate the temperature at county population centroids. County estimates were produced with elevation as a covariate. Performance of models was assessed by comparing adjusted R 2 , mean squared error, root mean squared error, and processing time. Prediction accuracy for split validation was above 90% for 11 months in ArcGIS and all 12 months in SAS. Cokriging in SAS achieved higher prediction accuracy and lower estimation bias as compared to cokriging in ArcGIS. County-level estimates produced by both packages were positively correlated (adjusted R 2 range=0.95 to 0.99); accuracy and precision improved with elevation as a covariate. Both methods from ArcGIS and SAS are reliable for U.S. county-level temperature estimates; However, ArcGIS's merits in spatial data pre-processing and processing time may be important considerations for software selection, especially for multi-year or multi-state projects.

Data Mining Supercomputing with SAS JMP® Genomics

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Richard S. Segall

2011-02-01

Full Text Available JMP® Genomics is statistical discovery software that can uncover meaningful patterns in high-throughput genomics and proteomics data. JMP® Genomics is designed for biologists, biostatisticians, statistical geneticists, and those engaged in analyzing the vast stores of data that are common in genomic research (SAS, 2009. Data mining was performed using JMP® Genomics on the two collections of microarray databases available from National Center for Biotechnology Information (NCBI for lung cancer and breast cancer. The Gene Expression Omnibus (GEO of NCBI serves as a public repository for a wide range of highthroughput experimental data, including the two collections of lung cancer and breast cancer that were used for this research. The results for applying data mining using software JMP® Genomics are shown in this paper with numerous screen shots.

Does age matter? Controls on the spatial organization of age and life expectancy in hillslopes, and implications for transport parameterization using rSAS

Science.gov (United States)

Kim, M.; Harman, C. J.; Troch, P. A. A.

2017-12-01

Hillslopes have been extensively explored as a natural fundamental unit for spatially-integrated hydrologic models. Much of this attention has focused on their use in predicting the quantity of discharge, but hillslope-based models can potentially be used to predict the composition of discharge (in terms of age and chemistry) if they can be parameterized terms of measurable physical properties. Here we present advances in the use of rank StorAge Selection (rSAS) functions to parameterize transport through hillslopes. These functions provide a mapping between the distribution of water ages in storage and in outfluxes in terms of a probability distribution over storage. It has previously been shown that rSAS functions are related to the relative partitioning and arrangement of flow pathways (and variabilities in that arrangement), while separating out the effect of changes in the overall rate of fluxes in and out. This suggests that rSAS functions should have a connection to the internal organization of flow paths in a hillslope.Using a combination of numerical modeling and theoretical analysis we examined: first, the controls of physical properties on internal spatial organization of age (time since entry), life expectancy (time to exit), and the emergent transit time distribution and rSAS functions; second, the possible parameterization of the rSAS function using the physical properties. The numerical modeling results showed the clear dependence of the rSAS function forms on the physical properties and relations between the internal organization and the rSAS functions. For the different rates of the exponential saturated hydraulic conductivity decline with depth the spatial organization of life expectancy varied dramatically and determined the rSAS function forms, while the organizaiton of the age showed less qualitative differences. Analytical solutions predicting this spatial organization and the resulting rSAS function were derived for simplified systems. These

Living Together v. Living Well Together: A Normative Examination of the SAS Case

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Lori G. Beaman

2016-04-01

Full Text Available The European Court of Human Rights decision in SAS from France illustrates how a policy and national mantra that ostensibly aims to enhance inclusiveness, ‘living together’, is legally deployed in a manner that may have the opposite effect. In essence, despite acknowledging the sincerity of SAS’s religious practice of wearing the niqab, and her agency in making the decision to do so, the Court focuses on radicalism and women’s oppression amongst Muslims. Taking the notion of living together as the beginning point, the paper explores the normative assumptions underlying this notion as illustrated in the judgment of the Court. An alternative approach, drawing on the work of Derrida for the notion of ‘living well together’ will be proposed and its implications for social inclusion explicated. The paper’s aim is to move beyond the specific example of SAS and France to argue that the SAS pattern of identifying particular values as ‘national values’, the deployment of those values through law, policy and public discourse, and their exclusionary effects is playing out in a number of Western democracies, including Canada, the country with which the author is most familiar. Because of this widespread dissemination of values and their framing as representative of who ‘we’ are, there is a pressing need to consider the potentially alienating effects of a specific manifestation of ‘living together’ and an alternative model of ‘living well together’.

ZEISIG: Approximate calculation of the intergranular gas fraction and the intragranular gas driven swelling for SAS4A

International Nuclear Information System (INIS)

Vaeth, L.

1993-02-01

A simple model has been developed for estimating, under steady-state irradiation conditions and for operational transients, the fraction of intergranular gas residing in fast reactor fuel and the intragranular gas driven swelling. The total gas retention in the fuel, the grain size and the irradiation conditions (mainly time dependent temperatures) must be known. Use has been made of parts of the fission gas model contained in the code LAKU and of results calculated with this code. The routine (named ZEISIG) is intended for insertion into the fast reactor accident model SAS4A as an extension of its fission gas model for steady-state reactor operation. (orig.) [de

SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules.

Science.gov (United States)

Dammermann, Alexander; Maddox, Paul S; Desai, Arshad; Oegema, Karen

2008-02-25

Centrioles are surrounded by pericentriolar material (PCM), which is proposed to promote new centriole assembly by concentrating gamma-tubulin. Here, we quantitatively monitor new centriole assembly in living Caenorhabditis elegans embryos, focusing on the conserved components SAS-4 and SAS-6. We show that SAS-4 and SAS-6 are coordinately recruited to the site of new centriole assembly and reach their maximum levels during S phase. Centriolar SAS-6 is subsequently reduced by a mechanism intrinsic to the early assembly pathway that does not require progression into mitosis. Centriolar SAS-4 remains in dynamic equilibrium with the cytoplasmic pool until late prophase, when it is stably incorporated in a step that requires gamma-tubulin and microtubule assembly. These results indicate that gamma-tubulin in the PCM stabilizes the nascent daughter centriole by promoting microtubule addition to its outer wall. Such a mechanism may help restrict new centriole assembly to the vicinity of preexisting parent centrioles that recruit PCM.

Development and validation of logistic prognostic models by predefined SAS-macros

Directory of Open Access Journals (Sweden)

Ziegler, Christoph

2006-02-01

Full Text Available In medical decision making about therapies or diagnostic procedures in the treatment of patients the prognoses of the course or of the magnitude of diseases plays a relevant role. Beside of the subjective attitude of the clinician mathematical models can help in providing such prognoses. Such models are mostly multivariate regression models. In the case of a dichotomous outcome the logistic model will be applied as the standard model. In this paper we will describe SAS-macros for the development of such a model, for examination of the prognostic performance, and for model validation. The rational for this developmental approach of a prognostic modelling and the description of the macros can only given briefly in this paper. Much more details are given in. These 14 SAS-macros are a tool for setting up the whole process of deriving a prognostic model. Especially the possibility of validating the model by a standardized software tool gives an opportunity, which is not used in general in published prognostic models. Therefore, this can help to develop new models with good prognostic performance for use in medical applications.

Non-linear Growth Models in Mplus and SAS

Science.gov (United States)

Grimm, Kevin J.; Ram, Nilam

2013-01-01

Non-linear growth curves or growth curves that follow a specified non-linear function in time enable researchers to model complex developmental patterns with parameters that are easily interpretable. In this paper we describe how a variety of sigmoid curves can be fit using the Mplus structural modeling program and the non-linear mixed-effects modeling procedure NLMIXED in SAS. Using longitudinal achievement data collected as part of a study examining the effects of preschool instruction on academic gain we illustrate the procedures for fitting growth models of logistic, Gompertz, and Richards functions. Brief notes regarding the practical benefits, limitations, and choices faced in the fitting and estimation of such models are included. PMID:23882134

SPSS and SAS programs for generalizability theory analyses.

Science.gov (United States)

Mushquash, Christopher; O'Connor, Brian P

2006-08-01

The identification and reduction of measurement errors is a major challenge in psychological testing. Most investigators rely solely on classical test theory for assessing reliability, whereas most experts have long recommended using generalizability theory instead. One reason for the common neglect of generalizability theory is the absence of analytic facilities for this purpose in popular statistical software packages. This article provides a brief introduction to generalizability theory, describes easy to use SPSS, SAS, and MATLAB programs for conducting the recommended analyses, and provides an illustrative example, using data (N = 329) for the Rosenberg Self-Esteem Scale. Program output includes variance components, relative and absolute errors and generalizability coefficients, coefficients for D studies, and graphs of D study results.

Numerical exploration of non-axisymmetric divertor closure in the small angle slot (SAS) divertor at DIII-D

Science.gov (United States)

Frerichs, H.; Schmitz, O.; Covele, B.; Feng, Y.; Guo, H. Y.; Hill, D.

2018-05-01

Numerical simulations of toroidal asymmetries in a tightly baffled small angle slot (SAS) divertor on the DIII-D tokamak show that toroidal asymmetries in divertor closure result in (non-axisymmetric) local onset of detachment within a density window of 10-15% on top of the nominal threshold separatrix density. The SAS divertor is explored at DIII-D for improving access to cold, dissipative/detached divertor conditions. The narrow width of the slot divertor coupled with a small magnetic field line-to-target angle facilitates the buildup of neutral density, thereby increasing radiative and neutrals-related (atoms and molecules) losses in the divertor. Small changes in the strike point location can be expected to have a large impact on divertor conditions. The combination of misaligned slot structure and non-axisymmetric perturbations to the magnetic field configuration causes the strike point to move along the divertor target plate, possibly leaving the divertor slot at some locations. The latter extreme case essentially introduces an opening in the divertor slot from where recycling neutrals can easily escape, and thereby degrade the performance of the slot divertor. Such a strike point dislocation is approximated by a finite gap in the divertor baffle for which 3D edge plasma and neutral gas simulations are performed with the EMC3-EIRENE code.

Design and implementation of reliability evaluation of SAS hard disk based on RAID card

Science.gov (United States)

Ren, Shaohua; Han, Sen

2015-10-01

Because of the huge advantage of RAID technology in storage, it has been widely used. However, the question associated with this technology is that the hard disk based on the RAID card can not be queried by Operating System. Therefore how to read the self-information and log data of hard disk has been a problem, while this data is necessary for reliability test of hard disk. In traditional way, this information can be read just suitable for SATA hard disk, but not for SAS hard disk. In this paper, we provide a method by using LSI RAID card's Application Program Interface, communicating with RAID card and analyzing the feedback data to solve the problem. Then we will get the necessary information to assess the SAS hard disk.

Composites reinforcement by rods a SAS study

CERN Document Server

Urban, V; Pyckhout-Hintzen, W; Richter, D; Straube, E

2002-01-01

The mechanical properties of composites are governed by size, shape and dispersion degree of so-called reinforcing particles. Polymeric fillers based on thermodynamically driven microphase separation of block copolymers offer the opportunity to study a model system of controlled rod-like filler particles. We chose a triblock copolymer (PBPSPB) and carried out SAS measurements with both X-rays and neutrons, in order to characterize separately the hard phase and the cross-linked PB matrix. The properties of the material depend strongly on the way that stress is carried and transferred between the soft matrix and the hard fibers. The failure of the strain-amplification concept and the change of topological contributions to the free energy and scattering factor have to be addressed. In this respect the composite shows a similarity to a two-network system, i.e. interpenetrating rubber and rod-like filler networks. (orig.)

A SAS macro for testing differences among three or more independent groups using Kruskal-Wallis and Nemenyi tests.

Science.gov (United States)

Liu, Yuewei; Chen, Weihong

2012-02-01

As a nonparametric method, the Kruskal-Wallis test is widely used to compare three or more independent groups when an ordinal or interval level of data is available, especially when the assumptions of analysis of variance (ANOVA) are not met. If the Kruskal-Wallis statistic is statistically significant, Nemenyi test is an alternative method for further pairwise multiple comparisons to locate the source of significance. Unfortunately, most popular statistical packages do not integrate the Nemenyi test, which is not easy to be calculated by hand. We described the theory and applications of the Kruskal-Wallis and Nemenyi tests, and presented a flexible SAS macro to implement the two tests. The SAS macro was demonstrated by two examples from our cohort study in occupational epidemiology. It provides a useful tool for SAS users to test the differences among three or more independent groups using a nonparametric method.

Adaptation and Validation of the Sexual Assertiveness Scale (SAS) in a Sample of Male Drug Users.

Science.gov (United States)

Vallejo-Medina, Pablo; Sierra, Juan Carlos

2015-04-21

The aim of the present study was to adapt and validate the Sexual Assertiveness Scale (SAS) in a sample of male drug users. A sample of 326 male drug users and 322 non-clinical males was selected by cluster sampling and convenience sampling, respectively. Results showed that the scale had good psychometric properties and adequate internal consistency reliability (Initiation = .66, Refusal = .74 and STD-P = .79). An evaluation of the invariance showed strong factor equivalence between both samples. A high and moderate effect of Differential Item Functioning was only found in items 1 and 14 (∆R 2 Nagelkerke = .076 and .037, respectively). We strongly recommend not using item 1 if the goal is to compare the scores of both groups, otherwise the comparison will be biased. Correlations obtained between the CSFQ-14 and the safe sex ratio and the SAS subscales were significant (CI = 95%) and indicated good concurrent validity. Scores of male drug users were similar to those of non-clinical males. Therefore, the adaptation of the SAS to drug users provides enough guarantees for reliable and valid use in both clinical practice and research, although care should be taken with item 1.

Plan empresa Publitis S.A.S: soluciones tecnológicas

OpenAIRE

Robledo Ceballos, Carlos Alberto; Rodríguez Velasco, Salvador

2011-01-01

RESUMEN: PubliTICs es una empresa de constitución privada creada bajo la reglamentación emitida para las Sociedades por Acciones Simplificadas, cuyo objeto principal es la prestación de servicios de Tecnologías de la Información y las Comunicaciones en el mercado de Colombia. PubliTICs S.A.S celebrará un contrato de Aliado Tecnológico y Comercial con las Empresas Municipales de Cali EMCALI EICE ESP, para prestar servicios de soluciones tecnológicas empresariales, aprovechando la infraestru...

O papel do community manager Toluna SAS: comunidade online interativa

OpenAIRE

Faria, Filipa Maria Ferreira Prego de

2014-01-01

Atualmente, a maioria das empresas encontra-se ligada a uma das ferramentas mais poderosas do mundo: a internet. Com o crescimento deste fenómeno, surgem aplicativos para melhorarem o seu aproveitamento. As empresas começam a usufruir da Web 2.0, que visa a utilização da internet como uma plataforma social. O trabalho aqui apresentado pretende fazer uma análise profunda da empresa online Toluna SAS e explicar o surgimento do profissional responsável por essa plataforma social, o Community Man...

The IAEA Transport Safety Appraisal Service (TranSAS)

International Nuclear Information System (INIS)

Dicke, G.J.

2004-01-01

Representatives of all Member States of the IAEA meet once a year in September at the General Conference in Vienna, Austria, to consider and approve the Agency's programme and budget and to address matters brought before it by the Board of Governors, the Director General, or Member States. In September 1998 the General Conference adopted resolution GC(42)/RES/13 on the Safety of Transport of Radioactive Materials. In adopting that resolution the General Conference recognized that compliance with regulations that take account of the IAEA Regulations for the Safe Transport of Radioactive Material (the IAEA Transport Regulations) is providing a high level of safety during the transport of radioactive material. Good compliance requires that the regulations are implemented effectively. The General Conference therefore requested the IAEA Secretariat to provide a service for carrying out, at the request of any State, an appraisal of the implementation of the Transport Regulations by that State. In response to this request the Director General of the IAEA offered such an appraisal service to all States in letter J1.01.Circ, dated 10 December 1998. The first Transport Safety Appraisal Service (TranSAS) was undertaken and completed at the request of Slovenia in 1999. A report on the results of that appraisal was published and released for general distribution in the early fall of 1999. In each of the General Conferences since 1998, resolutions focused on transport safety have commended the Secretariat for establishing the TranSAS, commended those States that have requested the appraisal service and encouraged other States to avail themselves of this service see GC(43)/RES/11, GC(44)/RES/17, GC(45)/RES/10, GC(46)/RES/9 and GC(47)/RES/7. Six appraisals have been carried out to date as follows: Slovenia, Brazil, United Kingdom, Turkey, Panama and France. This presentation provides an overview of the Transport Safety Appraisal Service and summarizes the major findings from the

The IAEA Transport Safety Appraisal Service (TranSAS)

Energy Technology Data Exchange (ETDEWEB)

Dicke, G.J. [International Atomic Energy Agency, Vienna (Austria)

2004-07-01

Representatives of all Member States of the IAEA meet once a year in September at the General Conference in Vienna, Austria, to consider and approve the Agency's programme and budget and to address matters brought before it by the Board of Governors, the Director General, or Member States. In September 1998 the General Conference adopted resolution GC(42)/RES/13 on the Safety of Transport of Radioactive Materials. In adopting that resolution the General Conference recognized that compliance with regulations that take account of the IAEA Regulations for the Safe Transport of Radioactive Material (the IAEA Transport Regulations) is providing a high level of safety during the transport of radioactive material. Good compliance requires that the regulations are implemented effectively. The General Conference therefore requested the IAEA Secretariat to provide a service for carrying out, at the request of any State, an appraisal of the implementation of the Transport Regulations by that State. In response to this request the Director General of the IAEA offered such an appraisal service to all States in letter J1.01.Circ, dated 10 December 1998. The first Transport Safety Appraisal Service (TranSAS) was undertaken and completed at the request of Slovenia in 1999. A report on the results of that appraisal was published and released for general distribution in the early fall of 1999. In each of the General Conferences since 1998, resolutions focused on transport safety have commended the Secretariat for establishing the TranSAS, commended those States that have requested the appraisal service and encouraged other States to avail themselves of this service see GC(43)/RES/11, GC(44)/RES/17, GC(45)/RES/10, GC(46)/RES/9 and GC(47)/RES/7. Six appraisals have been carried out to date as follows: Slovenia, Brazil, United Kingdom, Turkey, Panama and France. This presentation provides an overview of the Transport Safety Appraisal Service and summarizes the major findings from

Modelling the detachment dependence on strike point location in the small angle slot divertor (SAS) with SOLPS

Science.gov (United States)

Casali, Livia; Covele, Brent; Guo, Houyang

2017-10-01

The new Small Angle Slot (SAS) divertor in DIII-D is characterized by a shallow-angle target enclosed by a slot structure about the strike point (SP). SOLPS modelling results of SAS have demonstrated divertor closure's utility in widening the range of acceptable densities for adequate heat handling. An extensive database of runs has been built to study the detachment dependence on SP location in SAS. Density scans show that lower Te at lower upstream density occur when the SP is at the critical location in the slot. The cooling front spreads across the entire target at higher densities, in agreement with experimental Langmuir probe measurements. A localized increase of the atomic and molecular density takes place near the SP, which reduces the target incident power density and facilitates detachment at lower upstream density. Systematic scans of variables such as power, transport, and viscosity have been carried out to assess the detachment sensitivity. Therein, a positive role of the viscosity is found. This work supported by DOE Contract Number DE-FC02-04ER54698.

tran-SAS v1.0: a numerical model to compute catchment-scale hydrologic transport using StorAge Selection functions

Directory of Open Access Journals (Sweden)

P. Benettin

2018-04-01

Full Text Available This paper presents the tran-SAS package, which includes a set of codes to model solute transport and water residence times through a hydrological system. The model is based on a catchment-scale approach that aims at reproducing the integrated response of the system at one of its outlets. The codes are implemented in MATLAB and are meant to be easy to edit, so that users with minimal programming knowledge can adapt them to the desired application. The problem of large-scale solute transport has both theoretical and practical implications. On the one side, the ability to represent the ensemble of water flow trajectories through a heterogeneous system helps unraveling streamflow generation processes and allows us to make inferences on plant–water interactions. On the other side, transport models are a practical tool that can be used to estimate the persistence of solutes in the environment. The core of the package is based on the implementation of an age master equation (ME, which is solved using general StorAge Selection (SAS functions. The age ME is first converted into a set of ordinary differential equations, each addressing the transport of an individual precipitation input through the catchment, and then it is discretized using an explicit numerical scheme. Results show that the implementation is efficient and allows the model to run in short times. The numerical accuracy is critically evaluated and it is shown to be satisfactory in most cases of hydrologic interest. Additionally, a higher-order implementation is provided within the package to evaluate and, if necessary, to improve the numerical accuracy of the results. The codes can be used to model streamflow age and solute concentration, but a number of additional outputs can be obtained by editing the codes to further advance the ability to understand and model catchment transport processes.

tran-SAS v1.0: a numerical model to compute catchment-scale hydrologic transport using StorAge Selection functions

Science.gov (United States)

Benettin, Paolo; Bertuzzo, Enrico

2018-04-01

This paper presents the tran-SAS package, which includes a set of codes to model solute transport and water residence times through a hydrological system. The model is based on a catchment-scale approach that aims at reproducing the integrated response of the system at one of its outlets. The codes are implemented in MATLAB and are meant to be easy to edit, so that users with minimal programming knowledge can adapt them to the desired application. The problem of large-scale solute transport has both theoretical and practical implications. On the one side, the ability to represent the ensemble of water flow trajectories through a heterogeneous system helps unraveling streamflow generation processes and allows us to make inferences on plant-water interactions. On the other side, transport models are a practical tool that can be used to estimate the persistence of solutes in the environment. The core of the package is based on the implementation of an age master equation (ME), which is solved using general StorAge Selection (SAS) functions. The age ME is first converted into a set of ordinary differential equations, each addressing the transport of an individual precipitation input through the catchment, and then it is discretized using an explicit numerical scheme. Results show that the implementation is efficient and allows the model to run in short times. The numerical accuracy is critically evaluated and it is shown to be satisfactory in most cases of hydrologic interest. Additionally, a higher-order implementation is provided within the package to evaluate and, if necessary, to improve the numerical accuracy of the results. The codes can be used to model streamflow age and solute concentration, but a number of additional outputs can be obtained by editing the codes to further advance the ability to understand and model catchment transport processes.

Identificación de Prácticas Empresariales para el Mejoramiento Continuo en Plusagro S.A.S.

OpenAIRE

Martín Correal, Alvaro Steven

2014-01-01

Este proyecto que se llevara a cabo en la compañía Plusagro S.A.S. la cual busca mejorar de forma sustancial la cultura organizacional de la compañía, para que desarrolle al máximo las ventajas competitivas que encuentra en el mercado, una de estas grandes ventajas es que al tener la exclusividad de su proveedor principal Kursan. Se vuelve de suma importancia saber que existen otras marcas en el mercado de los productos agrícolas que ofrece Plusagro S.A.S. pero se ha encontrado en común acuer...

Determining hyporheic storage using the rSAS model in urban restored streams.

Science.gov (United States)

Stoll, E.; Putnam, S. M.; Cosans, C.; Harman, C. J.

2017-12-01

One aim of stream restoration is to increase the connectivity of the stream with the hyporheic zone, which is important for processes like denitrification. This study analyzed transects of different restoration techniques in an urban stream, Stony Run in Baltimore, Maryland. The extent of the hyporheic zone was determined using a combination of salt slug injection tracer studies to determine the breakthrough curves and the rank StorAge Selection (rSAS) model. Previous studies using salt tracer injections have often focused on the shape of the breakthrough curve and the transit time distributions of streams to infer indicies correlated with hyporheic zone storage. This study uses the rSAS model to determine the volume of storage that must be turning over to produce the breakthrough curve. This study looked at transects of two different restoration techniques, one with floodplain rehabilitation and one without. Both transects had cross vanes and pool and riffle systems and only differed in the steepness of the banks surrounding the stream. The utility and accuracy of rSAS method was found to be heavily dependent on accurate flow rates. To avoid potential skew in the results, normalized, relatively flow rate-independent metric of storage were compared among transects to reduce error resulting from the flow rate. The results suggested that stream water was retained for longer in a larger storage volume in the transect that did not have floodplain rehabilitation. When compared to the storage of a natural stream with similar geomorphologic characteristics, the restored transect without floodplain rehabilitation had a larger storage volume than the natural stream. The restored transect with floodplain rehabilitation not only had a smaller storage volume than the restored section without rehabilitation, but also had a smaller storage volume than the natural stream with similar bank slopes. This suggests that the floodplain restoration does not significantly contribute to

Assessment of SFR reactor safety issues: Part II: Analysis results of ULOF transients imposed on a variety of different innovative core designs with SAS-SFR

Energy Technology Data Exchange (ETDEWEB)

Kruessmann, R., E-mail: regina.kruessmann@kit.edu [Karlsruhe Institute of Technology, Institute of Neutron Physics and Reactor Technology INR, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Ponomarev, A.; Pfrang, W.; Struwe, D. [Karlsruhe Institute of Technology, Institute of Neutron Physics and Reactor Technology INR, Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen (Germany); Champigny, J.; Carluec, B. [AREVA, 10, rue J. Récamier, 69456 Lyon Cedex 06 (France); Schmitt, D.; Verwaerde, D. [EDF R& D, 1 avenue du général de Gaulle, 92140 Clamart (France)

2015-04-15

Highlights: • Comparison of different core designs for a sodium-cooled fast reactor. • Safety assessment with the code system SAS-SFR. • Unprotected Loss of Flow (ULOF) scenario. • Sodium boiling and core melting cannot be avoided. • A net negative Na void effect provides more grace time prior to local SA destruction. - Abstract: In the framework of cooperation agreements between KIT-INR and AREVA SAS NP as well as between KIT-INR and EDF R&D in the years 2008–2013, the evaluation of severe transient behavior in sodium-cooled fast reactors (SFRs) was investigated. In Part I of this contribution, the efficiency of newly conceived prevention and mitigation measures was investigated for unprotected loss-of-flow (ULOF), unprotected loss-of-heat-sink (ULOHS) and the unprotected transient-overpower (UTOP) transients. In this second part, consequence analyses were performed for the initiation phase of different unprotected loss-of-flow (ULOF) scenarios imposed on a variety of different core design options of SFRs. The code system SAS-SFR was used for this purpose. Results of analyses for cases postulating unavailability of prevention measures as shut-down systems, passive and/or active additional devices show that entering into an energetic power excursion as a consequence of the initiation phase of a ULOF cannot be avoided for those core designs with a cumulative void reactivity feedback larger than zero. However, even for core designs aiming at values of the void reactivity less than zero it is difficult to find system design characteristics which prevent the transient entering into partial core destruction. Further studies of the transient core and system behavior would require codes dedicated to specific aspects of transition phase analyses and of in-vessel material relocation analyses.

Cerebral scintigraphy by 99mTc-HMPAO in sleep apnea syndromes (SAS) during the wakeful state

International Nuclear Information System (INIS)

Tainturier, C.; Benamor, M.; Hausser-Hauw, C.; Rakotonanahary, D.; Fleury, B.

1997-01-01

The SAS is associated to cerebral hemodynamic modifications and to a high frequency of cerebro-vascular accidents. The aim of this study was to verify, during wakeful state, the cerebral hemodynamic in 14 patients afflicted with SAS of various intensity (Apnea Index = 5-120/h). 555 MBq of 99m Tc-HMPAO were injected in patients maintained awake. The images were obtained 20 minutes after injection by mean of a double-head chamber equipped with fan-beam collimators. They were interpreted visually by two independent readers. Anomalies of cerebral fixation were observed in 12/14 patients. They were small sores of diffuse hypo-fixations, with a 'riddly' aspect (4 cases), sores of bi-temporal hypo-fixation with a right- or left- hemispheric predominance (6 cases), or right fronto-temporal hypo-fixations (2 cases). The cerebral fixation anomalies were reported in the SASs. Ficker et al (1997) have shown in-sleep frontal hypo-perfusions in 5/14 apneic patients, reversible under continuous positive airing pressure (CPAP). In conclusion, anomalies of cerebral fixation exist in SAS-carrying patients, even in the wakeful state. Questions about hypoperfusion, pre-lacunar syndrome, atrophy still remain. A check of this study is planned after the CPAP treatment to determine the hemodynamic or anatomic origin and the anomaly reversibility

Cosmic radiation and airline pilots. Exposure patterns of Norwegian SAS-pilots 1960 to 1994. Revised Version

International Nuclear Information System (INIS)

Tveten, U.

1999-02-01

The present report is a revised version of an earlier report (IFE/KR/E-96/008). The revision has been carried out since a completely new version of the computational tool has recently been released. All calculations have been redone. The work which is presented in this report is part of a Norwegian epidemiological project, carried out in cooperation between Institute for Energy Technology (IFE), the Norwegian Cancer Registry (NCR) and the Norwegian Radiation Protection Authority (NRPA). Originating from the Norwegian project, a number of similar projects have been started in a number of European countries. The present report lays the ground for estimation of individual exposure histories to cosmic radiation of pilots employed by the the Scandinavian Airlines System (SAS). The result presented in this report (radiation dose rates for the different types of aircraft in the different years) were calculated with the most recent computer program for this purpose, the CARI-5E from the United States Civil Aviation Authority. The other major sources of information used as basis for this work is the collection of old SAS time tables found the the SAS Museum at Fornebu Airport in Oslo, and information provided by members of the Pilots Association in Norway

Cosmic radiation and airline pilots. Exposure patterns of Norwegian SAS-pilots 1960 to 1994. Revised Version

Energy Technology Data Exchange (ETDEWEB)

Tveten, U

1999-02-01

The present report is a revised version of an earlier report (IFE/KR/E-96/008). The revision has been carried out since a completely new version of the computational tool has recently been released. All calculations have been redone. The work which is presented in this report is part of a Norwegian epidemiological project, carried out in cooperation between Institute for Energy Technology (IFE), the Norwegian Cancer Registry (NCR) and the Norwegian Radiation Protection Authority (NRPA). Originating from the Norwegian project, a number of similar projects have been started in a number of European countries. The present report lays the ground for estimation of individual exposure histories to cosmic radiation of pilots employed by the the Scandinavian Airlines System (SAS). The result presented in this report (radiation dose rates for the different types of aircraft in the different years) were calculated with the most recent computer program for this purpose, the CARI-5E from the United States Civil Aviation Authority. The other major sources of information used as basis for this work is the collection of old SAS time tables found the the SAS Museum at Fornebu Airport in Oslo, and information provided by members of the Pilots Association in Norway.

Cerebral scintigraphy by {sup 99m}Tc-HMPAO in sleep apnea syndromes (SAS) during the wakeful state; Scintigraphie cerebrale au Tc99m-HMPAO dans les syndromes d`apnees du sommeil (SAS) pendant l`etat de veille

Energy Technology Data Exchange (ETDEWEB)

Tainturier, C.; Benamor, M.; Hausser-Hauw, C.; Rakotonanahary, D.; Fleury, B. [CMC FOCH 92150 SURESNES (France)

1997-12-31

The SAS is associated to cerebral hemodynamic modifications and to a high frequency of cerebro-vascular accidents. The aim of this study was to verify, during wakeful state, the cerebral hemodynamic in 14 patients afflicted with SAS of various intensity (Apnea Index = 5-120/h). 555 MBq of {sup 99m}Tc-HMPAO were injected in patients maintained awake. The images were obtained 20 minutes after injection by mean of a double-head chamber equipped with fan-beam collimators. They were interpreted visually by two independent readers. Anomalies of cerebral fixation were observed in 12/14 patients. They were small sores of diffuse hypo-fixations, with a `riddly` aspect (4 cases), sores of bi-temporal hypo-fixation with a right- or left- hemispheric predominance (6 cases), or right fronto-temporal hypo-fixations (2 cases). The cerebral fixation anomalies were reported in the SASs. Ficker et al (1997) have shown in-sleep frontal hypo-perfusions in 5/14 apneic patients, reversible under continuous positive airing pressure (CPAP). In conclusion, anomalies of cerebral fixation exist in SAS-carrying patients, even in the wakeful state. Questions about hypoperfusion, pre-lacunar syndrome, atrophy still remain. A check of this study is planned after the CPAP treatment to determine the hemodynamic or anatomic origin and the anomaly reversibility

Development and application of the automated Monte Carlo biasing procedure in SAS4

International Nuclear Information System (INIS)

Tang, J.S.; Broadhead, B.L.

1993-01-01

An automated approach for biasing Monte Carlo shielding calculations is described. In particular, adjoint fluxes from a one-dimensional discrete-ordinates calculation are used to generate biasing parameters for a three-dimensional Monte Carlo calculation. The automated procedure consisting of cross-section processing, adjoint flux determination, biasing parameter generation, and the initiation of a MORSE-SGC/S Monte Carlo calculation has been implemented in the SAS4 module of the SCALE computer code system. The automated procedure has been used extensively in the investigation of both computational and experimental benchmarks for the NEACRP working group on shielding assessment of transportation packages. The results of these studies indicate that with the automated biasing procedure, Monte Carlo shielding calculations of spent fuel casks can be easily performed with minimum effort and that accurate results can be obtained at reasonable computing cost. The systematic biasing approach described in this paper can also be applied to other similar shielding problems

Development and psychometric properties of the Suicidality: Treatment Occurring in Paediatrics (STOP) Suicidality Assessment Scale (STOP-SAS) in children and adolescents.

Science.gov (United States)

Flamarique, I; Santosh, P; Zuddas, A; Arango, C; Purper-Ouakil, D; Hoekstra, P J; Coghill, D; Schulze, U; Dittmann, R W; Buitelaar, J K; Lievesley, K; Frongia, R; Llorente, C; Méndez, I; Sala, R; Fiori, F; Castro-Fornieles, J

2016-12-13

To create a self-reported, internet-based questionnaire for the assessment of suicide risk in children and adolescents. As part of the EU project 'Suicidality: Treatment Occurring in Paediatrics' (STOP project), we developed web-based Patient Reported Outcome Measures (PROMs) for children and adolescents and for proxy reports by parents and clinicians in order to assess suicidality. Based on a literature review, expert panels and focus groups of patients, we developed the items of the STOP Suicidality Assessment Scale (STOP-SAS) in Spanish and English, translated it into four more languages, and optimized it for web-based presentation using the HealthTracker TM platform. Of the total 19 questions developed for the STOP-SAS, four questions that assess low-level suicidality were identified as screening questions (three of them for use with children, and all four for use with adolescents, parents and clinicians). A total of 395 adolescents, 110 children, 637 parents and 716 clinicians completed the questionnaire using the HealthTracker TM , allowing us to evaluate the internal consistency and convergent validity of the STOP-SAS with the clinician-rated Columbia Suicide Severity Rating Scale (C-SSRS). Validity was also assessed with the receiver operating characteristic (ROC) area of the STOP-SAS with the C-SSRS. The STOP-SAS comprises 19 items in its adolescent, parent, and clinician versions, and 14 items in its children's version. Good internal consistency was found for adolescents (Cronbach's alpha: 0.965), children (Cronbach's alpha: 0.922), parents (Cronbach's alpha: 0.951) and clinicians (Cronbach's alpha: 0.955) versions. A strong correlation was found between the STOP-SAS and the C-SSRS for adolescents (r:0.670), parents (r:0.548), clinicians (r:0.863) and children (r:0.654). The ROC area was good for clinicians' (0.917), adolescents' (0.834) and parents' (0.756) versions but only fair (0.683) for children's version. The STOP-SAS is a comprehensive, web

Social Anxiety Scale for Adolescents (SAS-A: Psychometric properties in a Spanish-speaking population

Directory of Open Access Journals (Sweden)

José Olivares

2005-01-01

Full Text Available El objetivo de este estudio instrumental fue estudiar la estructura factorial y propiedades psicométricas de la Escala de Ansiedad Social para Adolescentes (SASA. Participaron 2407 adolescentes (1263 chicos y 1144 chicas, con una edad media de 15 años, alumnos de nueve institutos de la región de Murcia. Los resultados obtenidos apoyan la estructura tri-factorial propuesta por los autores de la escala (FNE, SAD-New, SAD-General. Se encontraron correlaciones interescalas significativas y niveles de consistencia interna elevados para las subescalas, así como respecto de los efectos del sexo en la puntuación SAS-A/Total y en sus subescalas, alcanzando las chicas las puntuaciones más elevadas. Sólo se hallaron diferencias significativas para la edad en la subescala FNE y no se constataron efectos de interacción entre los dos factores. Estos hallazgos parecen avalar el uso de la SAS-A en población adolescente de habla española.

Riik võib lüüa SAS-i esmaspäevaks Estonian Airi omanikeringist välja / Erik Müürsepp, Mikk Salu

Index Scriptorium Estoniae

Müürsepp, Erik

2008-01-01

SAS osaleb Estonian Airþile lisakapitali eraldamises ainult juhul, kui Eesti riik müüb oma osaluses lennukompaniis SAS-ile. Peaminister Andrus Ansipi ning majandus- ja kommunikatsiooniminister Juhan Partsi seisukoht

Pravděpodobnostní rozdělení v programu SAS

OpenAIRE

Rosypal, Martin

2009-01-01

The aim of this work is to elaborate the metodology of creation of custom add-ins for statistical application SAS Enterprise Guide and create one of these that would enable to simplify the calculation of quantiles, values of probability mass function (probability density function respectively) and cumulative distribution function and further based on user's specifications create an appropriate graph. In connection with content of this add-in, the presented work includes the recherche from bac...

A SAS(®) macro implementation of a multiple comparison post hoc test for a Kruskal-Wallis analysis.

Science.gov (United States)

Elliott, Alan C; Hynan, Linda S

2011-04-01

The Kruskal-Wallis (KW) nonparametric analysis of variance is often used instead of a standard one-way ANOVA when data are from a suspected non-normal population. The KW omnibus procedure tests for some differences between groups, but provides no specific post hoc pair wise comparisons. This paper provides a SAS(®) macro implementation of a multiple comparison test based on significant Kruskal-Wallis results from the SAS NPAR1WAY procedure. The implementation is designed for up to 20 groups at a user-specified alpha significance level. A Monte-Carlo simulation compared this nonparametric procedure to commonly used parametric multiple comparison tests. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Proteomic analysis of cellular response induced by boron neutron capture reaction in human squamous cell carcinoma SAS cells

International Nuclear Information System (INIS)

Sato, Akira; Itoh, Tasuku; Imamichi, Shoji; Kikuhara, Sota; Fujimori, Hiroaki; Hirai, Takahisa; Saito, Soichiro; Sakurai, Yoshinori; Tanaka, Hiroki; Nakamura, Hiroyuki; Suzuki, Minoru

2015-01-01

To understand the mechanism of cell death induced by boron neutron capture reaction (BNCR), we performed proteome analyses of human squamous tumor SAS cells after BNCR. Cells were irradiated with thermal neutron beam at KUR after incubation under boronophenylalanine (BPA)(+) and BPA(−) conditions. BNCR mainly induced typical apoptosis in SAS cells 24 h post-irradiation. Proteomic analysis in SAS cells suggested that proteins functioning in endoplasmic reticulum, DNA repair, and RNA processing showed dynamic changes at early phase after BNCR and could be involved in the regulation of cellular response to BNCR. We found that the BNCR induces fragments of endoplasmic reticulum-localized lymphoid-restricted protein (LRMP). The fragmentation of LRMP was also observed in the rat tumor graft model 20 hours after BNCT treatment carried out at the National Nuclear Center of the Republic of Kazakhstan. These data suggest that dynamic changes of LRMP could be involved during cellular response to BNCR. - Highlights: • BNCR in human squamous carcinoma cells caused typical apoptotic features. • BNCR induced fragments of LRMP, in human squamous carcinoma and rat tumor model. • The fragmentation of LRMP could be involved in cellular response to BNCR.

Technical support for a proposed decay heat guide using SAS2H/ORIGEN-S data

International Nuclear Information System (INIS)

Hermann, O.W.; Parks, C.V.; Renier, J.P.

1994-09-01

Major revisions are proposed to the current US Nuclear Regulatory Commission decay heat rate guide entitled ''Regulatory Guide 3.54, Spent Fuel Heat Generation in an Independent Spent Fuel Storage Installation,'' using a new data base produced by the SAS2H analysis sequence of the SCALE-4 system. The data base for the proposed guide revision has been significantly improved by increasing the number and range of parameters that generally characterize pressurized-water-reactor (PWR) and boiling-water-reactor (BWR) spent fuel assemblies. Using generic PWR and BWR assembly models, calculations were performed with each model for six different burnups at each of three separate specific powers to produce heat rates at 20 cooling times in the range of 1 to 110 y. The proposed procedure specifies proper interpolation formulae for the tabulated heat generation rates. Adjustment formulae for the interpolated values are provided to account for differences in initial 235 U enrichment and changes in the specific power of a cycle from the average value. Finally, safety factor formulae were derived as a function of burnup, cooling time, and type of reactor. The proposed guide revision was designed to be easier to use. Also, the complete data base and guide procedure is incorporated into an interactive code called LWRARC which can be executed on a personal computer. The report shows adequate comparisons of heat rates computed by SAS2H/ORIGEN-S and measurements for 10 BWR and 10 PWR fuel assemblies. The average differences of the computed minus the measured heat rates of fuel assemblies were -07 ± 2.6% for the BWR and 1.5 ± 1.3% for the PWR. In addition, a detailed analysis of the proposed procedure indicated the method and equations to be valid

Distribution of sasX, pvl, and qacA/B genes in epidemic methicillin-resistant Staphylococcus aureus strains isolated from East China

Directory of Open Access Journals (Sweden)

Kong H

2018-01-01

Full Text Available Haishen Kong,1,2 Lingmei Fang,3 Rujin Jiang,4 Jixiang Tong2 1State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; 2Key Laboratory of Clinical In Vitro Diagnostic Techniques of Zhejiang Province, Department of Laboratory Medicine, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China; 3Clinical Laboratory, Chunan First People’s Hospital, Zhejiang Province People’s Hospital Chunan Branch, Hangzhou, China; 4Clinical Laboratory, Yuhang Hospital of Traditional Chinese Medicine, Hangzhou, China Background: Methicillin-resistant Staphylococcus aureus (MRSA is a major nosocomial pathogen. Various virulence and antiseptic-resistant factors increase the pathogenicity of MRSA strains and allow for increased infection rates.Purpose: The purpose of this study was to investigate the prevalence and distribution of virulence-associated and antiseptic-resistant genes from epidemic MRSA strains isolated from East China.Methods: A newly designed multiplex PCR assay was used to assess whether the virulence-associated genes sasX and pvl and the chlorhexidine tolerance gene qacA/B were present in 189 clinical isolates of MRSA. Multilocus sequence typing (MLST and Staphylococcal protein A (spa typing of these isolates were also performed. The frequency of these genes in isolates with epidemic sequence types (STs was investigated. Results: Twenty STs and 36 spa types with five epidemic clones (ST5-t311, ST59-t437, ST5-t002, ST239-t030, and ST239-t037 were identified. The prevalence of sasX, pvl, and qacA/B in all isolates was 5.8%, 10.1%, and 20.1%, respectively. The prevalences of these genes in isolates with ST5, ST59, ST239, and other ST genetic backgrounds were all significantly different (P<0.001. Isolates that had the highest frequency of sas

Adaptive Tests of Significance Using Permutations of Residuals with R and SAS

CERN Document Server

O'Gorman, Thomas W

2012-01-01

Provides the tools needed to successfully perform adaptive tests across a broad range of datasets Adaptive Tests of Significance Using Permutations of Residuals with R and SAS illustrates the power of adaptive tests and showcases their ability to adjust the testing method to suit a particular set of data. The book utilizes state-of-the-art software to demonstrate the practicality and benefits for data analysis in various fields of study. Beginning with an introduction, the book moves on to explore the underlying concepts of adaptive tests, including:Smoothing methods and normalizing transforma

Cross-cultural adaptation of the Sport Anxiety Scale-2 (SAS-2 for the Brazilian context

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Viviane Vedovato Silva-Rocha

Full Text Available Abstract Objective To present the process of cross-cultural adaptation of the Sport Anxiety Scale-2 (SAS-2 for the Brazilian context. Method The following stages were used: translation into Brazilian Portuguese by independent translators, elaboration of a synthesis version, back-translation, evaluation by experts and pretest with target population. Results All the stages of cross-cultural adaptation were completed, and in the majority of items evaluated, good concordance between experts was obtained (≥ 80%. Suggested adjustments were compiled into the consensus version by the two authors, with the resulting material being considered adequate in the pretest (and thus no further changes were needed. Termed as “Escala de Ansiedade Esportiva-2,” the final version was considered by the main author of the original scale as an official version in Brazilian Portuguese. Conclusions In view of the fulfilment of all steps suggested for the cross-cultural adaptation process, the SAS-2 is now available in Brazilian Portuguese to be tested for its psychometric qualities.

SASqPCR: robust and rapid analysis of RT-qPCR data in SAS.

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Daijun Ling

Full Text Available Reverse transcription quantitative real-time PCR (RT-qPCR is a key method for measurement of relative gene expression. Analysis of RT-qPCR data requires many iterative computations for data normalization and analytical optimization. Currently no computer program for RT-qPCR data analysis is suitable for analytical optimization and user-controllable customization based on data quality, experimental design as well as specific research aims. Here I introduce an all-in-one computer program, SASqPCR, for robust and rapid analysis of RT-qPCR data in SAS. This program has multiple macros for assessment of PCR efficiencies, validation of reference genes, optimization of data normalizers, normalization of confounding variations across samples, and statistical comparison of target gene expression in parallel samples. Users can simply change the macro variables to test various analytical strategies, optimize results and customize the analytical processes. In addition, it is highly automatic and functionally extendable. Thus users are the actual decision-makers controlling RT-qPCR data analyses. SASqPCR and its tutorial are freely available at http://code.google.com/p/sasqpcr/downloads/list.

Stratospheric Air Sub-sampler (SAS) and its application to analysis of Delta O-17(CO2) from small air samples collected with an AirCore

NARCIS (Netherlands)

Mrozek, Dorota Janina; van der Veen, Carina; Hofmann, Magdalena E. G.; Chen, Huilin; Kivi, Rigel; Heikkinen, Pauli; Rockmann, Thomas

2016-01-01

We present the set-up and a scientific application of the Stratospheric Air Sub-sampler (SAS), a device to collect and to store the vertical profile of air collected with an AirCore (Karion et al., 2010) in numerous sub-samples for later analysis in the laboratory. The SAS described here is a 20m

Recent progress on the R and D program of the seismic attenuation system (SAS) proposed for the advanced gravitational wave detector, LIGO II

International Nuclear Information System (INIS)

Bertolini, A.; Cella, G.; Chenyang, W.; Salvo, R. de; Kovalik, J.; Marka, S.; Sannibale, V.; Takamori, A.; Tariq, H.; Viboud, N.

2001-01-01

High-performance Seismic Isolation Systems in gravitational wave interferometers are needed not only to increase the sensitivity of the detectors but also to guarantee long periods of stable operation. SAS is essentially a system which produces the required in-band seismic isolation by use of passive mechanical filters and actively reduces the out of band seismic noise using inertial damping. The passive isolation is achieved for all the 6 degrees of freedom, with an Inverted Pendulum and a chain of single wire pendula whose masses are the Geometrical Anti-Spring Filters (GASF). The active control is applied to reduce mainly the noise below 4 Hz and to damp the resonances of the chain acting from the inverted pendulum table. Here we present a brief overview of SAS and recent results achieved from the full scale SAS prototype

SAS Macros for Calculation of Population Attributable Fraction in a Cohort Study Design

Directory of Open Access Journals (Sweden)

Maarit A. Laaksonen

2011-08-01

Full Text Available The population attributable fraction (PAF is a useful measure for quantifying the impact of exposure to certain risk factors on a particular outcome at the population level. Recently, new model-based methods for the estimation of PAF and its confidence interval for different types of outcomes in a cohort study design have been proposed. In this paper, we introduce SAS macros implementing these methods and illustrate their application with a data example on the impact of different risk factors on type 2 diabetes incidence.

ORNL-SAS: Versatile software for calculation of small-angle x-ray and neutron scattering intensity profiles from arbitrary structures

International Nuclear Information System (INIS)

Heller, William T; Tjioe, Elina

2007-01-01

ORNL-SAS is software for calculating solution small-angle scattering intensity profiles from any structure provided in the Protein Data Bank format and can also compare the results with experimental data

Plan de negocio para la creación de la empresa Itech S.A.S.

OpenAIRE

2012-01-01

ITEH S.A.S ofrecerá el servicio de consultoría y asesoría en el uso y gestión de las tecnologías de la información y las comunicaciones a las pymes del sector servicios, específicamente en el subsector jurídico, con el fin de apoyar sus procesos de negocio y fortalecer la competitividad de las mismas.

Usual Dietary Intakes: SAS Macros for Estimating Ratios of Two Dietary Components that are Consumed Nearly Every Day

Science.gov (United States)

The following SAS macros can be used to create a bivariate distribution of usual intake of two dietary components that are consumed nearly every day and to calculate percentiles of the population distribution of the ratio of usual intakes.

The Music Therapy Session Assessment Scale (MT-SAS): Validation of a new tool for music therapy process evaluation.

Science.gov (United States)

Raglio, Alfredo; Gnesi, Marco; Monti, Maria Cristina; Oasi, Osmano; Gianotti, Marta; Attardo, Lapo; Gontero, Giulia; Morotti, Lara; Boffelli, Sara; Imbriani, Chiara; Montomoli, Cristina; Imbriani, Marcello

2017-11-01

Music therapy (MT) interventions are aimed at creating and developing a relationship between patient and therapist. However, there is a lack of validated observational instruments to consistently evaluate the MT process. The purpose of this study was the validation of Music Therapy Session Assessment Scale (MT-SAS), designed to assess the relationship between therapist and patient during active MT sessions. Videotapes of a single 30-min session per patient were considered. A pilot study on the videotapes of 10 patients was carried out to help refine the items, define the scoring system and improve inter-rater reliability among the five raters. Then, a validation study on 100 patients with different clinical conditions was carried out. The Italian MT-SAS was used throughout the process, although we also provide an English translation. The final scale consisted of 7 binary items accounting for eye contact, countenance, and nonverbal and sound-music communication. In the pilot study, raters were found to share an acceptable level of agreement in their assessments. Explorative factorial analysis disclosed a single homogeneous factor including 6 items (thus supporting an ordinal total score), with only the item about eye contact being unrelated to the others. Moreover, the existence of 2 different archetypal profiles of attuned and disattuned behaviours was highlighted through multiple correspondence analysis. As suggested by the consistent results of 2 different analyses, MT-SAS is a reliable tool that globally evaluates sonorous-musical and nonverbal behaviours related to emotional attunement and empathetic relationship between patient and therapist during active MT sessions. Copyright © 2017 John Wiley & Sons, Ltd.

Enhancing the solubility and bioavailability of poorly water-soluble drugs using supercritical antisolvent (SAS) process.

Science.gov (United States)

Abuzar, Sharif Md; Hyun, Sang-Min; Kim, Jun-Hee; Park, Hee Jun; Kim, Min-Soo; Park, Jeong-Sook; Hwang, Sung-Joo

2018-03-01

Poor water solubility and poor bioavailability are problems with many pharmaceuticals. Increasing surface area by micronization is an effective strategy to overcome these problems, but conventional techniques often utilize solvents and harsh processing, which restricts their use. Newer, green technologies, such as supercritical fluid (SCF)-assisted particle formation, can produce solvent-free products under relatively mild conditions, offering many advantages over conventional methods. The antisolvent properties of the SCFs used for microparticle and nanoparticle formation have generated great interest in recent years, because the kinetics of the precipitation process and morphologies of the particles can be accurately controlled. The characteristics of the supercritical antisolvent (SAS) technique make it an ideal tool for enhancing the solubility and bioavailability of poorly water-soluble drugs. This review article focuses on SCFs and their properties, as well as the fundamentals of overcoming poorly water-soluble drug properties by micronization, crystal morphology control, and formation of composite solid dispersion nanoparticles with polymers and/or surfactants. This article also presents an overview of the main aspects of the SAS-assisted particle precipitation process, its mechanism, and parameters, as well as our own experiences, recent advances, and trends in development. Copyright © 2017 Elsevier B.V. All rights reserved.

Cdk1 Phosphorylates Drosophila Sas-4 to Recruit Polo to Daughter Centrioles and Convert Them to Centrosomes.

Science.gov (United States)

Novak, Zsofia A; Wainman, Alan; Gartenmann, Lisa; Raff, Jordan W

2016-06-20

Centrosomes and cilia are organized by a centriole pair comprising an older mother and a younger daughter. Centriole numbers are tightly regulated, and daughter centrioles (which assemble in S phase) cannot themselves duplicate or organize centrosomes until they have passed through mitosis. It is unclear how this mitotic "centriole conversion" is regulated, but it requires Plk1/Polo kinase. Here we show that in flies, Cdk1 phosphorylates the conserved centriole protein Sas-4 during mitosis. This creates a Polo-docking site that helps recruit Polo to daughter centrioles and is required for the subsequent recruitment of Asterless (Asl), a protein essential for centriole duplication and mitotic centrosome assembly. Point mutations in Sas-4 that prevent Cdk1 phosphorylation or Polo docking do not block centriole disengagement during mitosis, but block efficient centriole conversion and lead to embryonic lethality. These observations can explain why daughter centrioles have to pass through mitosis before they can duplicate and organize a centrosome. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

The Proposal of Co-Branding Strategy PT. XYZ and SAS in Automotive Sector in SPAIN Market to Increase PT. XYZ Reputation in International Market

OpenAIRE

Putra A, Freggy Griyatta; Nasution, Reza Ashari

2012-01-01

The development of the lubricant market in the Asia-Pacific, Africa, Middle East, and South America is an opportunity for PT.XYZ in the future. PT. XYZ wants to improve their brand image through co-branding with the SAS company as one of the local oil company in Spain. The study also analyzes the co-branding strategy through Joint Venture of PT. XYZ with SAS to improve the company's brand image in the International market. The conceptual framework of this research started from the goal of PT....

Plan de empresa DROP S.A.S. artículos y accesorios para mascotas

OpenAIRE

2012-01-01

Este trabajo es un plan de empresa que determina la viabilidad del proyecto DROP S.A.S, que tiene como finalidad la producción y comercialización de artículos para mascotas. Para lograr este fin, se ha realizado el plan de mercadeo, plan de producción, plan de organización y plan financiero, al hacer un estudio detallado de cada uno de estos módulos Inicialmente se elaboró el plan de mercadeo, en el que se hizo un análisis de las fuerzas del entorno, dentro del cual, se encuentra el estud...

[Calculating Pearson residual in logistic regressions: a comparison between SPSS and SAS].

Science.gov (United States)

Xu, Hao; Zhang, Tao; Li, Xiao-song; Liu, Yuan-yuan

2015-01-01

To compare the results of Pearson residual calculations in logistic regression models using SPSS and SAS. We reviewed Pearson residual calculation methods, and used two sets of data to test logistic models constructed by SPSS and STATA. One model contained a small number of covariates compared to the number of observed. The other contained a similar number of covariates as the number of observed. The two software packages produced similar Pearson residual estimates when the models contained a similar number of covariates as the number of observed, but the results differed when the number of observed was much greater than the number of covariates. The two software packages produce different results of Pearson residuals, especially when the models contain a small number of covariates. Further studies are warranted.

Evaluation of sleep apnea syndrome (SAS) with low field MR fluoroscopy

International Nuclear Information System (INIS)

Fukatsu, Hiroshi; Ando, Yoko; Ishigaki, Takeo; Okada, Tamotsu.

1995-01-01

Eight cases of clinically diagnosed sleep apnea syndrome (SAS) and two normal volunteers were studied with low field MR fluoroscopy in order to monitor the waking and sleeping status of the upper airway. MR fluoroscopy revealed that only the sleeping patients showed occlusions of the upper airway. This technique provided us with useful information about the level, frequency and duration of occlusion in each case. Four of the eight patients demonstrated simple retropalatal occlusion, whereas the other four demonstrated mixed retropalatal and retropalato-retroglossal occlusion. Thus long-time monitoring, which is only possible with MR fluoroscopy, is needed to appreciate the complex nature of the disease. In addition, the comfortable surroundings and low noise level provided by the low field enabled physiological study to be performed without any tranquilizers in most of the patients, which is again only possible with MR fluoroscopy. MR fluoroscopy may become a tool of great clinical value, providing much important information for disease evaluation and treatment selection. (author)

Cosmic radiation and airline pilots. Exposure patterns of Norwegian pilots flying aircraft not used by SAS

International Nuclear Information System (INIS)

Tveten, U.

1997-05-01

The work which is presented in this report is part of a Norwegian epidemiological project, carried out in cooperation between Institutt for Energiteknikk (IFE), the Norwegian Cancer Registry (NCR) and the Norwegian Radiation Protection Authority (NRPA). The project has been partially financed by the Norwegian Research Council. Originating from the Norwegian project, a number of similar projects have been started or are in the planning stage in a number of European countries. The present report lays the ground for estimation of individual exposure histories to cosmic radiation of pilots flying a great diversity of different aircrafts. Aircrafts that appear in the time-tables of the Scandinavian Airline System (SAS) have been treated in an earlier report. The results presented in this report (radiation doserates for the different types of aircrafts in the different years) will, in a later stage of the project be utilized to estimate the individual radiation exposure histories. The major sources of information used as basis for the work in this report is information provided by several active pilots, members of the Pilots Associations, along with calculations performed using US Federal Aviation Administration's computer code CARI-3N. 2 refs

Cosmic radiation and airline pilots. Exposure patterns of Norwegian pilots flying aircraft not used by SAS

Energy Technology Data Exchange (ETDEWEB)

Tveten, U.

1997-05-01

The work which is presented in this report is part of a Norwegian epidemiological project, carried out in cooperation between Institutt for Energiteknikk (IFE), the Norwegian Cancer Registry (NCR) and the Norwegian Radiation Protection Authority (NRPA). The project has been partially financed by the Norwegian Research Council. Originating from the Norwegian project, a number of similar projects have been started or are in the planning stage in a number of European countries. The present report lays the ground for estimation of individual exposure histories to cosmic radiation of pilots flying a great diversity of different aircrafts. Aircrafts that appear in the time-tables of the Scandinavian Airline System (SAS) have been treated in an earlier report. The results presented in this report (radiation doserates for the different types of aircrafts in the different years) will, in a later stage of the project be utilized to estimate the individual radiation exposure histories. The major sources of information used as basis for the work in this report is information provided by several active pilots, members of the Pilots Associations, along with calculations performed using US Federal Aviation Administration`s computer code CARI-3N. 2 refs.

%lrasch_mml: A SAS Macro for Marginal Maximum Likelihood Estimation in Longitudinal Polytomous Rasch Models

Directory of Open Access Journals (Sweden)

Maja Olsbjerg

2015-10-01

Full Text Available Item response theory models are often applied when a number items are used to measure a unidimensional latent variable. Originally proposed and used within educational research, they are also used when focus is on physical functioning or psychological wellbeing. Modern applications often need more general models, typically models for multidimensional latent variables or longitudinal models for repeated measurements. This paper describes a SAS macro that fits two-dimensional polytomous Rasch models using a specification of the model that is sufficiently flexible to accommodate longitudinal Rasch models. The macro estimates item parameters using marginal maximum likelihood estimation. A graphical presentation of item characteristic curves is included.

Annotated Computer Output for Illustrative Examples of Clustering Using the Mixture Method and Two Comparable Methods from SAS.

Science.gov (United States)

1987-06-26

BUREAU OF STANDAR-S1963-A Nw BOM -ILE COPY -. 4eo .?3sa.9"-,,A WIN* MAT HEMATICAL SCIENCES _*INSTITUTE AD-A184 687 DTICS!ELECTE ANNOTATED COMPUTER OUTPUT...intoduction to the use of mixture models in clustering. Cornell University Biometrics Unit Technical Report BU-920-M and Mathematical Sciences Institute...mixture method and two comparable methods from SAS. Cornell University Biometrics Unit Technical Report BU-921-M and Mathematical Sciences Institute

SPSS and SAS programs for determining the number of components using parallel analysis and velicer's MAP test.

Science.gov (United States)

O'Connor, B P

2000-08-01

Popular statistical software packages do not have the proper procedures for determining the number of components in factor and principal components analyses. Parallel analysis and Velicer's minimum average partial (MAP) test are validated procedures, recommended widely by statisticians. However, many researchers continue to use alternative, simpler, but flawed procedures, such as the eigenvalues-greater-than-one rule. Use of the proper procedures might be increased if these procedures could be conducted within familiar software environments. This paper describes brief and efficient programs for using SPSS and SAS to conduct parallel analyses and the MAP test.

A SAS-based solution to evaluate study design efficiency of phase I pediatric oncology trials via discrete event simulation.

Science.gov (United States)

Barrett, Jeffrey S; Jayaraman, Bhuvana; Patel, Dimple; Skolnik, Jeffrey M

2008-06-01

Previous exploration of oncology study design efficiency has focused on Markov processes alone (probability-based events) without consideration for time dependencies. Barriers to study completion include time delays associated with patient accrual, inevaluability (IE), time to dose limiting toxicities (DLT) and administrative and review time. Discrete event simulation (DES) can incorporate probability-based assignment of DLT and IE frequency, correlated with cohort in the case of DLT, with time-based events defined by stochastic relationships. A SAS-based solution to examine study efficiency metrics and evaluate design modifications that would improve study efficiency is presented. Virtual patients are simulated with attributes defined from prior distributions of relevant patient characteristics. Study population datasets are read into SAS macros which select patients and enroll them into a study based on the specific design criteria if the study is open to enrollment. Waiting times, arrival times and time to study events are also sampled from prior distributions; post-processing of study simulations is provided within the decision macros and compared across designs in a separate post-processing algorithm. This solution is examined via comparison of the standard 3+3 decision rule relative to the "rolling 6" design, a newly proposed enrollment strategy for the phase I pediatric oncology setting.

SPSS and SAS procedures for estimating indirect effects in simple mediation models.

Science.gov (United States)

Preacher, Kristopher J; Hayes, Andrew F

2004-11-01

Researchers often conduct mediation analysis in order to indirectly assess the effect of a proposed cause on some outcome through a proposed mediator. The utility of mediation analysis stems from its ability to go beyond the merely descriptive to a more functional understanding of the relationships among variables. A necessary component of mediation is a statistically and practically significant indirect effect. Although mediation hypotheses are frequently explored in psychological research, formal significance tests of indirect effects are rarely conducted. After a brief overview of mediation, we argue the importance of directly testing the significance of indirect effects and provide SPSS and SAS macros that facilitate estimation of the indirect effect with a normal theory approach and a bootstrap approach to obtaining confidence intervals, as well as the traditional approach advocated by Baron and Kenny (1986). We hope that this discussion and the macros will enhance the frequency of formal mediation tests in the psychology literature. Electronic copies of these macros may be downloaded from the Psychonomic Society's Web archive at www.psychonomic.org/archive/.

SPSS and SAS programs for addressing interdependence and basic levels-of-analysis issues in psychological data.

Science.gov (United States)

O'Connor, Brian P

2004-02-01

Levels-of-analysis issues arise whenever individual-level data are collected from more than one person from the same dyad, family, classroom, work group, or other interaction unit. Interdependence in data from individuals in the same interaction units also violates the independence-of-observations assumption that underlies commonly used statistical tests. This article describes the data analysis challenges that are presented by these issues and presents SPSS and SAS programs for conducting appropriate analyses. The programs conduct the within-and-between-analyses described by Dansereau, Alutto, and Yammarino (1984) and the dyad-level analyses described by Gonzalez and Griffin (1999) and Griffin and Gonzalez (1995). Contrasts with general multilevel modeling procedures are then discussed.

Computational procedures for probing interactions in OLS and logistic regression: SPSS and SAS implementations.

Science.gov (United States)

Hayes, Andrew F; Matthes, Jörg

2009-08-01

Researchers often hypothesize moderated effects, in which the effect of an independent variable on an outcome variable depends on the value of a moderator variable. Such an effect reveals itself statistically as an interaction between the independent and moderator variables in a model of the outcome variable. When an interaction is found, it is important to probe the interaction, for theories and hypotheses often predict not just interaction but a specific pattern of effects of the focal independent variable as a function of the moderator. This article describes the familiar pick-a-point approach and the much less familiar Johnson-Neyman technique for probing interactions in linear models and introduces macros for SPSS and SAS to simplify the computations and facilitate the probing of interactions in ordinary least squares and logistic regression. A script version of the SPSS macro is also available for users who prefer a point-and-click user interface rather than command syntax.

GéoSAS: A modular and interoperable Open Source Spatial Data Infrastructure for research

Directory of Open Access Journals (Sweden)

R. Bera

2015-05-01

Full Text Available To-date, the commonest way to deal with geographical information and processes still appears to consume local resources, i.e. locally stored data processed on a local desktop or server. The maturity and subsequent growing use of OGC standards to exchange data on the World Wide Web, enhanced in Europe by the INSPIRE Directive, is bound to change the way people (and among them research scientists, especially in environmental sciences make use of, and manage, spatial data. A clever use of OGC standards can help scientists to better store, share and use data, in particular for modelling. We propose a framework for online processing by making an intensive use of OGC standards. We illustrate it using the Spatial Data Infrastructure (SDI GéoSAS which is the SDI set up for researchers’ needs in our department. It is based on the existing open source, modular and interoperable Spatial Data Architecture geOrchestra.

GéoSAS: A modular and interoperable Open Source Spatial Data Infrastructure for research

Science.gov (United States)

Bera, R.; Squividant, H.; Le Henaff, G.; Pichelin, P.; Ruiz, L.; Launay, J.; Vanhouteghem, J.; Aurousseau, P.; Cudennec, C.

2015-05-01

To-date, the commonest way to deal with geographical information and processes still appears to consume local resources, i.e. locally stored data processed on a local desktop or server. The maturity and subsequent growing use of OGC standards to exchange data on the World Wide Web, enhanced in Europe by the INSPIRE Directive, is bound to change the way people (and among them research scientists, especially in environmental sciences) make use of, and manage, spatial data. A clever use of OGC standards can help scientists to better store, share and use data, in particular for modelling. We propose a framework for online processing by making an intensive use of OGC standards. We illustrate it using the Spatial Data Infrastructure (SDI) GéoSAS which is the SDI set up for researchers' needs in our department. It is based on the existing open source, modular and interoperable Spatial Data Architecture geOrchestra.

Planteamiento estratégico de Pronalfo S.A.S. y Reingeniería del Proceso de Producción

OpenAIRE

Fajardo Castillo, Erika Esperanza; Quiroga Arguello, Luz Andrea

2012-01-01

Pronalfo S.A.S es una empresa dedicada a la elaboración de núcleos balanceados como materia prima para la alimentación animal, fue creada hace 7 años y se encuentra en la etapa de crecimiento y posicionamiento en el mercado. Es necesario establecer el planeamiento estratégico mediante la definición de misión, visión, objetivos y estrategias, para tener clara su razón de ser y proyectándose al futuro estableciendo una ventaja competitiva mediante estrategias que le permitan mantenerse en ...

Desarrollo de las competencias en los altos ejecutivos y mandos medios de estrella petrolera de Colombia S.A.S.

OpenAIRE

Díaz Hurtado, David Hernando; Villamarín Rincón, Bibiana

2012-01-01

La situación actual de la compañía Estrella Petrolera de Colombia S.A.S, está demandando un replanteamiento en el manejo su departamento de Recursos Humanos. Como parte de la estrategia de la compañía para afrontar los retos del negocio se desea adoptar el proceso de Gestión Humana basada en competencias el cual brindará la orientación necesaria para el desarrollo del conocimiento y el aprendizaje permanente. Los métodos de gestión de Recursos Humanos basados en competencias facilita...

Cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of an inositol monophosphatase family protein (SAS2203) from Staphylococcus aureus MSSA476

International Nuclear Information System (INIS)

Bhattacharyya, Sudipta; Dutta, Debajyoti; Ghosh, Ananta Kumar; Das, Amit Kumar

2011-01-01

The cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of an inositol monophosphatase family protein (SAS2203) from S. aureus MSSA476 is reported. The gene product of the sas2203 ORF of Staphylococcus aureus MSSA476 encodes a 30 kDa molecular-weight protein with a high sequence resemblance (29% identity) to tetrameric inositol monophosphatase from Thermotoga maritima. The protein was cloned, expressed, purified to homogeneity and crystallized. Crystals appeared in several conditions and good diffraction-quality crystals were obtained from 0.2 M Li 2 SO 4 , 20% PEG 3350, 0.1 M HEPES pH 7.0 using the sitting-drop vapour-diffusion method. A complete diffraction data set was collected to 2.6 Å resolution using a Rigaku MicroMax-007 HF Cu Kα X-ray generator and a Rigaku R-AXIS IV ++ detector. The diffraction data were consistent with the orthorhombic space group P2 1 2 1 2 1 , with unit-cell parameters a = 49.98, b = 68.35, c = 143.79 Å, α = β = γ = 90°, and the crystal contained two molecules in the asymmetric unit

SAS Enterprise Data Integration Server - A Complete Solution Designed To Meet the Full Spectrum of Enterprise Data Integration Needs

Directory of Open Access Journals (Sweden)

Silvia BOLOHAN

2012-05-01

Full Text Available This paper is about why is Data Integration important for organisations around the world. Organizations struggle daily with the challenges of large distributed data volumes, inconsistently defined data across disparate systems and the high expectations of data consumers who depend on information to be correct, complete and available when they need it. SAS Enterprise Data Integration Server provides a comprehensive solution that enables organizations to solve these challenges in a timely, cost-effective manner with the ability to efficiently manage data integration projects on an enterprise scale, increasing overall productivity and reducing the total cost of ownership.

NParCov3: A SAS/IML Macro for Nonparametric Randomization-Based Analysis of Covariance

Directory of Open Access Journals (Sweden)

Richard C. Zink

2012-07-01

Full Text Available Analysis of covariance serves two important purposes in a randomized clinical trial. First, there is a reduction of variance for the treatment effect which provides more powerful statistical tests and more precise confidence intervals. Second, it provides estimates of the treatment effect which are adjusted for random imbalances of covariates between the treatment groups. The nonparametric analysis of covariance method of Koch, Tangen, Jung, and Amara (1998 defines a very general methodology using weighted least-squares to generate covariate-adjusted treatment effects with minimal assumptions. This methodology is general in its applicability to a variety of outcomes, whether continuous, binary, ordinal, incidence density or time-to-event. Further, its use has been illustrated in many clinical trial settings, such as multi-center, dose-response and non-inferiority trials.NParCov3 is a SAS/IML macro written to conduct the nonparametric randomization-based covariance analyses of Koch et al. (1998. The software can analyze a variety of outcomes and can account for stratification. Data from multiple clinical trials will be used for illustration.

[Evaluation of the factorial and metric equivalence of the Sexual Assertiveness Scale (SAS) by sex].

Science.gov (United States)

Sierra, Juan Carlos; Santos-Iglesias, Pablo; Vallejo-Medina, Pablo

2012-05-01

Sexual assertiveness refers to the ability to initiate sexual activity, refuse unwanted sexual activity, and use contraceptive methods to avoid sexually transmitted diseases, developing healthy sexual behaviors. The Sexual Assertiveness Scale (SAS) assesses these three dimensions. The purpose of this study is to evaluate, using structural equation modeling and differential item functioning, the equivalence of the scale between men and women. Standard scores are also provided. A total of 4,034 participants from 21 Spanish provinces took part in the study. Quota sampling method was used. Results indicate a strict equivalent dimensionality of the Sexual Assertiveness Scale across sexes. One item was flagged by differential item functioning, although it does not affect the scale. Therefore, there is no significant bias in the scale when comparing across sexes. Standard scores show similar Initiation assertiveness scores for men and women, and higher scores on Refusal and Sexually Transmitted Disease Prevention for women. This scale can be used on men and women with sufficient psychometric guarantees.

Validation of SCALE code package on high performance neutron shields

International Nuclear Information System (INIS)

Bace, M.; Jecmenica, R.; Smuc, T.

1999-01-01

The shielding ability and other properties of new high performance neutron shielding materials from the KRAFTON series have been recently published. A comparison of the published experimental and MCNP results for the two materials of the KRAFTON series, with our own calculations has been done. Two control modules of the SCALE-4.4 code system have been used, one of them based on one dimensional radiation transport analysis (SAS1) and other based on the three dimensional Monte Carlo method (SAS3). The comparison of the calculated neutron dose equivalent rates shows a good agreement between experimental and calculated results for the KRAFTON-N2 material.. Our results indicate that the N2-M-N2 sandwich type is approximately 10% inferior as neutron shield to the KRAFTON-N2 material. All values of neutron dose equivalent obtained by SAS1 are approximately 25% lower in comparison with the SAS3 results, which indicates proportions of discrepancies introduced by one-dimensional geometry approximation.(author)

Análisis de las causas de rotación de personal de la empresa Holcrest S.A.S

OpenAIRE

Domínguez Olaya, María Katherine

2015-01-01

La retención del personal es una parte importante de los esfuerzos del área de recursos humanos y de la organización en general, ya que la desvinculación representa costos y daño de la imagen organizacional. Es así como el estudio y análisis de la retención de personal se ha convertido en parte de la gestión organizacional. Con la presente investigación se busca analizar las causas que inciden en la rotación de personal en la empresa prestadora de servicios del grupo Holcim, Holcrest S.A.S, u...

The zebrafish maternal-effect gene cellular atoll encodes the centriolar component sas-6 and defects in its paternal function promote whole genome duplication.

Science.gov (United States)

Yabe, Taijiro; Ge, Xiaoyan; Pelegri, Francisco

2007-12-01

A female-sterile zebrafish maternal-effect mutation in cellular atoll (cea) results in defects in the initiation of cell division starting at the second cell division cycle. This phenomenon is caused by defects in centrosome duplication, which in turn affect the formation of a bipolar spindle. We show that cea encodes the centriolar coiled-coil protein Sas-6, and that zebrafish Cea/Sas-6 protein localizes to centrosomes. cea also has a genetic paternal contribution, which when mutated results in an arrested first cell division followed by normal cleavage. Our data supports the idea that, in zebrafish, paternally inherited centrosomes are required for the first cell division while maternally derived factors are required for centrosomal duplication and cell divisions in subsequent cell cycles. DNA synthesis ensues in the absence of centrosome duplication, and the one-cycle delay in the first cell division caused by cea mutant sperm leads to whole genome duplication. We discuss the potential implications of these findings with regards to the origin of polyploidization in animal species. In addition, the uncoupling of developmental time and cell division count caused by the cea mutation suggests the presence of a time window, normally corresponding to the first two cell cycles, which is permissive for germ plasm recruitment.

Overly long centrioles and defective cell division upon excess of the SAS-4-related protein CPAP.

Science.gov (United States)

Kohlmaier, Gregor; Loncarek, Jadranka; Meng, Xing; McEwen, Bruce F; Mogensen, Mette M; Spektor, Alexander; Dynlacht, Brian D; Khodjakov, Alexey; Gönczy, Pierre

2009-06-23

The centrosome is the principal microtubule organizing center (MTOC) of animal cells. Accurate centrosome duplication is fundamental for genome integrity and entails the formation of one procentriole next to each existing centriole, once per cell cycle. The procentriole then elongates to eventually reach the same size as the centriole. The mechanisms that govern elongation of the centriolar cylinder and their potential relevance for cell division are not known. Here, we show that the SAS-4-related protein CPAP is required for centrosome duplication in cycling human cells. Furthermore, we demonstrate that CPAP overexpression results in the formation of abnormally long centrioles. This also promotes formation of more than one procentriole in the vicinity of such overly long centrioles, eventually resulting in the presence of supernumerary MTOCs. This in turn leads to multipolar spindle assembly and cytokinesis defects. Overall, our findings suggest that centriole length must be carefully regulated to restrict procentriole number and thus ensure accurate cell division.

Diseño de una estrategia que posicione a Transporte Comercial la Estrella SAS como una empresa mas competitiva en el sector transporte

OpenAIRE

Cifuentes Amaya, Mauricio Andrés

2017-01-01

La elaboración de este proyecto busca explicar los factores que actualmente afectan al sector transporte (Costos elevados, sobreoferta, chatarrización, fletes elevados, hacinamiento, Etc.) y, a partir de esto, diseñar estrategias que le permitan a la empresa de transporte: TRANSPORTE COMERCIAL LA ESTRELLA SAS, convertirse en una empresa más competitiva dentro del sector en el que se desenvuelve. El planteamiento estratégico estudiado se fundamenta en el modelo de las 5 fuerzas de Michael P...

Impact of sacubitril-valsartan combination in patients with chronic heart failure and sleep apnoea syndrome: the ENTRESTO-SAS study design.

Science.gov (United States)

Jaffuel, Dany; Molinari, Nicolas; Berdague, Philippe; Pathak, Atul; Galinier, Michel; Dupuis, Marion; Ricci, Jean-Etienne; Mallet, Jean-Pierre; Bourdin, Arnaud; Roubille, François

2018-06-01

Sleep-disordered breathing (SDB) is a highly prevalent co-morbidity in patients with chronic heart failure (CHF) and can play a detrimental role in the pathophysiology course of CHF. However, the best way to manage SDB in CHF remains a matter of debate. Sacubitril-valsartan has been included in the 2016 European Society of Cardiology guidelines as an alternative to angiotensin-converting enzyme inhibitors to further reduce the risk of progression of CHF, CHF hospitalization, and death in ambulatory patients. Sacubitril and valsartan are good candidates for correcting SDB of CHF patients because their known mechanisms of action are likely to counteract the pathophysiology of SDB in CHF. The ENTRESTO-SAS trial is a 3-month, multicentric, prospective, open-label real-life cohort study. Patients eligible for sacubitril-valsartan treatment (i.e. adults with left ventricular ejection fraction ≤35%, who remain symptomatic despite optimal treatment with an angiotensin-converting enzyme inhibitor, a beta-blocker, and a mineralocorticoid receptor antagonist) will be evaluated before and after 3 months of treatment (nocturnal ventilatory polygraphy, echocardiography, laboratory testing, and quality-of-life and SDB questionnaires). The primary outcome is the change in the Apnoea-Hypopnoea Index, before and after 3 months of treatment. One hundred twenty patients are required to detect a significant 20% improvement of the Apnoea-Hypopnoea Index with a power of 90% at an alpha risk of 5%. In the context of the SERVE-HF study, physicians are waiting for new trials and alternative therapies. We sought to assess in the ENTRESTO-SAS trial whether sacubitril-valsartan could improve the outcome of SDB in CHF patients. © 2018 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology.

Fibrinogen species as resolved by HPLC-SAXS data processing within the UltraScan Solution Modeler (US-SOMO) enhanced SAS module.

Science.gov (United States)

Brookes, Emre; Pérez, Javier; Cardinali, Barbara; Profumo, Aldo; Vachette, Patrice; Rocco, Mattia

2013-12-01

Fibrinogen is a large heterogeneous aggregation/degradation-prone protein playing a central role in blood coagulation and associated pathologies, whose structure is not completely resolved. When a high-molecular-weight fraction was analyzed by size-exclusion high-performance liquid chromatography/small-angle X-ray scattering (HPLC-SAXS), several composite peaks were apparent and because of the stickiness of fibrinogen the analysis was complicated by severe capillary fouling. Novel SAS analysis tools developed as a part of the UltraScan Solution Modeler ( US-SOMO ; http://somo.uthscsa.edu/), an open-source suite of utilities with advanced graphical user interfaces whose initial goal was the hydrodynamic modeling of biomacromolecules, were implemented and applied to this problem. They include the correction of baseline drift due to the accumulation of material on the SAXS capillary walls, and the Gaussian decomposition of non-baseline-resolved HPLC-SAXS elution peaks. It was thus possible to resolve at least two species co-eluting under the fibrinogen main monomer peak, probably resulting from in-column degradation, and two others under an oligomers peak. The overall and cross-sectional radii of gyration, molecular mass and mass/length ratio of all species were determined using the manual or semi-automated procedures available within the US-SOMO SAS module. Differences between monomeric species and linear and sideways oligomers were thus identified and rationalized. This new US-SOMO version additionally contains several computational and graphical tools, implementing functionalities such as the mapping of residues contributing to particular regions of P ( r ), and an advanced module for the comparison of primary I ( q ) versus q data with model curves computed from atomic level structures or bead models. It should be of great help in multi-resolution studies involving hydrodynamics, solution scattering and crystallographic/NMR data.

SAS and SPSS macros to calculate standardized Cronbach's alpha using the upper bound of the phi coefficient for dichotomous items.

Science.gov (United States)

Sun, Wei; Chou, Chih-Ping; Stacy, Alan W; Ma, Huiyan; Unger, Jennifer; Gallaher, Peggy

2007-02-01

Cronbach's a is widely used in social science research to estimate the internal consistency of reliability of a measurement scale. However, when items are not strictly parallel, the Cronbach's a coefficient provides a lower-bound estimate of true reliability, and this estimate may be further biased downward when items are dichotomous. The estimation of standardized Cronbach's a for a scale with dichotomous items can be improved by using the upper bound of coefficient phi. SAS and SPSS macros have been developed in this article to obtain standardized Cronbach's a via this method. The simulation analysis showed that Cronbach's a from upper-bound phi might be appropriate for estimating the real reliability when standardized Cronbach's a is problematic.

[Reflection around the code of ethics for nurses].

Science.gov (United States)

Depoire, Nathalie

2017-09-01

The code of ethics for nurses highlights the values, principles and obligations which characterise our profession. It also emphasises the conditions required to enable nurses to perform their professional practice with the autonomy granted to them by the Public Health Code. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Scafom International BV v. Lorraine Tubes S.A.S.: a case review of changing circumstances under the United Nations Convention on International Sale of Goods (CISG of 1980

Directory of Open Access Journals (Sweden)

Amalina AHMAD TAJUDIN

2014-12-01

Full Text Available This paper analyses the Belgium Supreme Court decision of Scafom International BV v. Lorraine Tubes S.A.S. The case involved a contract of sale of volatile goods ie steel tubes whereby a fixed-price contract caused it to be unenforceable because of the 70% market price increase just before the goods were delivered to the buyer. While the seller requested for renegotiation, for a higher contract price, the buyer refused to come to terms with the former. The court, by virtue of the United Nations sales law, held that renegotiation was the appropriate remedy in such a situation. In addition, the paper tests the different possible outcomes of this decision under the English Sale of Goods Act 1979, as well as the US Uniform Commercial Code. The finding of this test proves that these two sales laws would have tackled the issue of volatile market differently from that of the United Nations’.

Diseño de un plan estratégico en el Instituto de Enfermedades Autoinmunes Renato Guzmán - IDEARG S.A.S.

OpenAIRE

Jiménez Serrano, Lorena; Ortegon Lancheros, Carolina

2012-01-01

IDEARG S.A.S es una Institución Prestadora de Servicios de Salud dedicada a la atención de pacientes con enfermedades autoinmunes. Dentro de su ordenación se encuentra una planta de personal organizada y comprometida con el progreso de la empresa. Sin embargo, existe una sentida necesidad de implementar estrategias que permitan el fortalecimiento interno de la institución y su posicionamiento en el mercado como una de las empresas de mayor prestigio en su campo de acción. Resulta oportuno...

Neutron and X-ray small angle scattering (S.A.S.) study of the amorphous alloy Tbsub(.25)Cusub(.75)

International Nuclear Information System (INIS)

Boucher, B.

1980-07-01

The magnetic properties of amorphous alloys REsub(x) Msub(x-1) (R.E.=heavy rare earths, M=Cu, Ag, Au) have been widely studied. They are of the speromagnetic type for x>=0.33 and are mictomagnetic for x -12 cm). Also the atomic volume of Terbium (approximately 33 A 3 ) is almost three times that of Copper (11.8 A 3 ) and Cu is less absorbant than Ag or Au. Tb alloys exhibit high magnetic ordering temperatures and important moments in contrast to the majority of other alloys of the same family. One inconvenience with Terbium, however, is the large (X-ray) fluorescence (lambda Cu). In order to confirm some interpretations of S.A.S., we were obliged to determine some physical parameters such as the density and porosity and to examine the sample with microscope. These results are also given here

Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros

Science.gov (United States)

Valeri, Linda; VanderWeele, Tyler J.

2012-01-01

Mediation analysis is a useful and widely employed approach to studies in the field of psychology and in the social and biomedical sciences. The contributions of this paper are several-fold. First we seek to bring the developments in mediation analysis for non linear models within the counterfactual framework to the psychology audience in an accessible format and compare the sorts of inferences about mediation that are possible in the presence of exposure-mediator interaction when using a counterfactual versus the standard statistical approach. Second, the work by VanderWeele and Vansteelandt (2009, 2010) is extended here to allow for dichotomous mediators and count outcomes. Third, we provide SAS and SPSS macros to implement all of these mediation analysis techniques automatically and we compare the types of inferences about mediation that are allowed by a variety of software macros. PMID:23379553

Diagnostico organizacional y formulación del plan estratégico de desarrollo para la empresa WPA Fauna y Ambiente S.A.S

OpenAIRE

Garavito Garavito, Gustavo Alfonso

2017-01-01

La presente oferta de servicios comprende la elaboración del diagnóstico Organizacional y formulación del plan estratégico de desarrollo para la empresa WPA Fauna y Ambiente S.A.S, utilizando modelos de administración tales como; el modelo Pestel, el modelo de Kast–Rozeinsweig, el modelo de cinco fuerzas de Porter, complementado con un análisis (DOFA) para así, a partir del análisis de los hallazgos formular el plan de desarrollo que permita a la organización enfocarse en una estrategia de me...

Plan de mejoramiento para el área de logística a nivel local de la compañía RotamAgrochemical Colombia S.A.S.

OpenAIRE

Gómez Susa, Martha Jannett; Morales Valero, Nadine Stella; Mosquera López, Diana Milena

2013-01-01

El trabajo pretende diseñar un plan de mejoramiento en el área logística que agregue valor, aumente la eficiencia y mejore los procesos de almacenamiento y distribución, gestión de inventarios y control de los productos agroquímicos de la Compañía RotamAgrochemical Colombia S.A.S., se formulan algunas recomendaciones para el mejoramiento de los procesos en las Áreas de almacenamiento, inventarios y seguridad industrial

Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros.

Science.gov (United States)

Valeri, Linda; Vanderweele, Tyler J

2013-06-01

Mediation analysis is a useful and widely employed approach to studies in the field of psychology and in the social and biomedical sciences. The contributions of this article are several-fold. First we seek to bring the developments in mediation analysis for nonlinear models within the counterfactual framework to the psychology audience in an accessible format and compare the sorts of inferences about mediation that are possible in the presence of exposure-mediator interaction when using a counterfactual versus the standard statistical approach. Second, the work by VanderWeele and Vansteelandt (2009, 2010) is extended here to allow for dichotomous mediators and count outcomes. Third, we provide SAS and SPSS macros to implement all of these mediation analysis techniques automatically, and we compare the types of inferences about mediation that are allowed by a variety of software macros. (PsycINFO Database Record (c) 2013 APA, all rights reserved).

Hotell Radisson SAS = Radisson SAS Hotel / Inga Raukas

Index Scriptorium Estoniae

Raukas, Inga, 1967-

2001-01-01

Projekteerija Arhitektuuribüroo Künnapu & Padrik. Arhitektid Vilen Künnapu, Ain Padrik, Eero Palm, Tarmo Maiste. Sisekujundajad Christian Lundwall, Jan Öberg. Konstruktsioonid: Teuvo Meriläinen, Jyrki Rautamäki. Projekt ja hotell valmis 2000. 12 ill.: korruste plaanid, sise- ja välisvaated

Análisis financiero de la empresa Neoris Colombia S.A.S. y el sector de tecnologías de información en Colombia

OpenAIRE

Chaparro Rojas, Laura Cristina

2016-01-01

El siguiente trabajo de grado para la Facultad de Administración de la Universidad del Rosario, tiene como objetivo principal realizar un análisis financiero de la compañía NEORIS COLOMBIA S.A.S., empresa resultante de las soluciones innovadoras que creó CEMEX, uno de los productores de cemento más grandes y rentables del mundo, y que se dedica a brindar consultoría interna de tecnología. Asimismo, indagar las implicaciones que tienen los cambios y el avance en los sistemas de implementación ...

[The impact of the code of ethics on training].

Science.gov (United States)

Tirand-Martin, Catherine

2017-09-01

The publication of the French code of ethics for nurses, in November 2016, has had an impact on the training of student nurses. In this context, appropriation of the code is clearly facilitated by the form and definition of the text which immediately reinforces students' commitment on the path to professionalization. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Numerical exploration of non-axisymmetric divertor closure in the small angle slot (SAS) divertor at DIII-D

Science.gov (United States)

Frerichs, Heinke; Schmitz, Oliver; Covele, Brent; Guo, Houyang; Hill, David; Feng, Yuhe

2017-10-01

In the Small Angle Slot (SAS) divertor in DIII-D, the combination of misaligned slot structure and non-axisymmetric perturbations to the magnetic field causes the strike point to vary radially along the divertor slot and even leave it at some toroidal locations. This effect essentially introduces an opening in the divertor slot from where recycling neutrals can easily escape, and thereby degrade performance of the slot divertor. This effect has been approximated by a finite gap in the divertor baffle. Simulations with EMC3-EIRENE show that a toroidally localized loss of divertor closure can result in non-axisymmetric divertor densities and temperatures. This introduces a density window of 10-15% on top of the nominal threshold separatrix density during which a non-axisymmetric onset of local detachment occurs, initially leaving the gap and up to 60 deg beyond that still attached. Conversely, the impact of such toroidally localized divertor perturbations on the toroidal symmetry of midplane separatrix conditions is small. This work has been funded by the U.S. Department of Energy under Early Career Award Grant DE-SC0013911, and Grant DE-FC02-04ER54698.

Nuclear safety code study

Energy Technology Data Exchange (ETDEWEB)

Hu, H.H.; Ford, D.; Le, H.; Park, S.; Cooke, K.L.; Bleakney, T.; Spanier, J.; Wilburn, N.P.; O' Reilly, B.; Carmichael, B.

1981-01-01

The objective is to analyze an overpower accident in an LMFBR. A simplified model of the primary coolant loop was developed in order to understand the instabilities encountered with the MELT III and SAS codes. The computer programs were translated for switching to the IBM 4331. Numerical methods were investigated for solving the neutron kinetics equations; the Adams and Gear methods were compared. (DLC)

Estudio de inteligencia de mercados para la importación de tubería de acero carbón para PSA Colombia S.A.S.

OpenAIRE

2012-01-01

Estudio de inteligencia de mercados para la importación de tuberia de acero carbon para PSA Colombia S.A.S, SCH 40 de 2" revisar la viabilidad de la compra local versus la compra en el exterior analizando tres proveedores Estados Unidos, China y Brasil. En el presente trabajo se estudian los mercados para la importación de tubería de Acero Carbón SCH40, se realiza el análisis de cada área del proceso de comercialización y se establece en términos técnicos, comerciales, financieros, logísticos...

[Student nurses and the code of ethics].

Science.gov (United States)

Trolliet, Julie

2017-09-01

Student nurses, just like all practising professionals, are expected to be aware of and to respect the code of ethics governing their profession. Since the publication of this code, actions to raise awareness of it and explain it to all the relevant players have been put in place. The French National Federation of Student Nurses decided to survey future professionals regarding this new text. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

[Promoting the code of ethics for nurses].

Science.gov (United States)

Chamboredon, Patrick; Lecointre, Brigitte

2017-09-01

The publication of the code of ethics for nurses requires the French National Order of Nurses' structures to undertake initiatives with the aim of promoting it as well as implementing the public service missions which have now been attributed to the Order. Each regional and departmental body has its role to play in raising awareness of this code and its application in the field. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Extension of the supercritical carbon dioxide brayton cycle to low reactor power operation: investigations using the coupled anl plant dynamics code-SAS4A/SASSYS-1 liquid metal reactor code system

International Nuclear Information System (INIS)

Moisseytsev, A.; Sienicki, J.J.

2012-01-01

Significant progress has been made on the development of a control strategy for the supercritical carbon dioxide (S-CO 2 ) Brayton cycle enabling removal of power from an autonomous load following Sodium-Cooled Fast Reactor (SFR) down to decay heat levels such that the S-CO 2 cycle can be used to cool the reactor until decay heat can be removed by the normal shutdown heat removal system or a passive decay heat removal system such as Direct Reactor Auxiliary Cooling System (DRACS) loops with DRACS in-vessel heat exchangers. This capability of the new control strategy eliminates the need for use of a separate shutdown heat removal system which might also use supercritical CO 2 . It has been found that this capability can be achieved by introducing a new control mechanism involving shaft speed control for the common shaft joining the turbine and two compressors following reduction of the load demand from the electrical grid to zero. Following disconnection of the generator from the electrical grid, heat is removed from the intermediate sodium circuit through the sodium-to-CO 2 heat exchanger, the turbine solely drives the two compressors, and heat is rejected from the cycle through the CO 2 -to-water cooler. To investigate the effectiveness of shaft speed control, calculations are carried out using the coupled Plant Dynamics Code-SAS4A/SASSYS-1 code for a linear load reduction transient for a 1000 MWt metallic-fueled SFR with autonomous load following. No deliberate motion of control rods or adjustment of sodium pump speeds is assumed to take place. It is assumed that the S-CO 2 turbomachinery shaft speed linearly decreases from 100 to 20% nominal following reduction of grid load to zero. The reactor power is calculated to autonomously decrease down to 3% nominal providing a lengthy window in time for the switchover to the normal shutdown heat removal system or for a passive decay heat removal system to become effective. However, the calculations reveal that the

SASSYS LMFBR systems code

International Nuclear Information System (INIS)

Dunn, F.E.; Prohammer, F.G.; Weber, D.P.

1983-01-01

The SASSYS LMFBR systems analysis code is being developed mainly to analyze the behavior of the shut-down heat-removal system and the consequences of failures in the system, although it is also capable of analyzing a wide range of transients, from mild operational transients through more severe transients leading to sodium boiling in the core and possible melting of clad and fuel. The code includes a detailed SAS4A multi-channel core treatment plus a general thermal-hydraulic treatment of the primary and intermediate heat-transport loops and the steam generators. The code can handle any LMFBR design, loop or pool, with an arbitrary arrangement of components. The code is fast running: usually faster than real time

Development of a coupled dynamics code with transport theory capability and application to accelerator driven systems transients

International Nuclear Information System (INIS)

Cahalan, J.E.; Ama, T.; Palmiotti, G.; Taiwo, T.A.; Yang, W.S.

2000-01-01

The VARIANT-K and DIF3D-K nodal spatial kinetics computer codes have been coupled to the SAS4A and SASSYS-1 liquid metal reactor accident and systems analysis codes. SAS4A and SASSYS-1 have been extended with the addition of heavy liquid metal (Pb and Pb-Bi) thermophysical properties, heat transfer correlations, and fluid dynamics correlations. The coupling methodology and heavy liquid metal modeling additions are described. The new computer code suite has been applied to analysis of neutron source and thermal-hydraulics transients in a model of an accelerator-driven minor actinide burner design proposed in an OECD/NEA/NSC benchmark specification. Modeling assumptions and input data generation procedures are described. Results of transient analyses are reported, with emphasis on comparison of P1 and P3 variational nodal transport theory results with nodal diffusion theory results, and on significance of spatial kinetics effects

Statistical core design methodology using the VIPRE thermal-hydraulics code

International Nuclear Information System (INIS)

Lloyd, M.W.; Feltus, M.A.

1995-01-01

An improved statistical core design methodology for developing a computational departure from nucleate boiling ratio (DNBR) correlation has been developed and applied in order to analyze the nominal 1.3 DNBR limit on Westinghouse Pressurized Water Reactor (PWR) cores. This analysis, although limited in scope, found that the DNBR limit can be reduced from 1.3 to some lower value and be accurate within an adequate confidence level of 95%, for three particular FSAR operational transients: turbine trip, complete loss of flow, and inadvertent opening of a pressurizer relief valve. The VIPRE-01 thermal-hydraulics code, the SAS/STAT statistical package, and the EPRI/Columbia University DNBR experimental data base were used in this research to develop the Pennsylvania State Statistical Core Design Methodology (PSSCDM). The VIPRE code was used to perform the necessary sensitivity studies and generate the EPRI correlation-calculated DNBR predictions. The SAS package used for these EPRI DNBR correlation predictions from VIPRE as a data set to determine the best fit for the empirical model and to perform the statistical analysis. (author)

Evaluación de la gestión de residuos derivados del proceso de impresión en Datapoint de Colombia S.A.S, y propuesta de mejora

OpenAIRE

Fino Gallego, Sandra Patricia; Gómez Gianine, Carol Ruchina; Ruano Reyes, Sandra Milena

2015-01-01

Este trabajo se centra en el análisis de las actividades desarrolladas en torno a los servicios de procesos de impresión que ofrece la organización DATAPOINT de Colombia SAS para identificar los puntos críticos en la gestión de los residuos de impresión y las decisiones tomadas por parte de los involucrados durante todo el proceso (proveedores, clientes y la empresa), con el fin de revisar medidas y estrategias que permitan fortalecer la gestión integral de residuos de impresión a partir d...

Aplicación de la GTC-34 y GTC-45 en una S.A.S de servicios en HSEQ: Estudio de caso

Directory of Open Access Journals (Sweden)

Olga Lucia Díaz Villamizar

2013-07-01

Full Text Available The goal of the project was the development of the Occupational Health Program and Risk Factor Outlook based on the Colombian Technical Standards GTC 34 and 45, for a SAS company working on HSEQ solutions. The outlook and the program were based on a diagnosis obtained through a survey filled out by the Manager and by checking the occupational health progress status through a “checklist”. With this information, a risk matrix was applied to each process, which complemented the Occupational Health Program design. Finally, the results of the project were socialized with all employees, and it is expected to be the starting point for the enterprise to build a culture of pre­vention and self-care. The implementation of the Occupational Health Program allows the studied company to comply with the Colombian law in Occupational Health, get the RUC, bid in the public and private sector, and initiate a process of S& S - OHSAS 18001: 07 standards certification.

ARP: A PC-compatible scheme for generating ORIGEN-S cross section library

International Nuclear Information System (INIS)

Leal, L.C.; Hermann, O.W.; Parks, C.V.

1995-01-01

The SAS2H sequence of the SCALE code system has been widely used for treating problems related to the characterization of nuclear systems for disposal, storage, and shipment. The calculations, in general, consist of determining the isotope compositions of the different materials present in the problem as a function of time, which subsequently enable determination of the heat generation and radiation source terms. In the SAS2H scheme, time-dependent material concentrations are obtained using the ORIGEN-S code based on a point-depletion calculation that utilizes problem-dependent cross-section libraries generated by distinct codes of the SAS2H sequence. In this paper we will be concerned with the methodology utilized in the SAS2H control module to create cross-section libraries for point-depletion calculations with the ORIGEN-S code. A brief description of the SAS2H scheme will be given, and a new capability, the automatic rapid processing (ARP), for generating problem-dependent ORIGEN-S cross-section libraries will be presented. Use of ARP can enable execution of ORIGEN-S on a personal computer with identical accuracy to that obtained with SAS2H

Estudio logístico en la empresa COMERFRUTAS de Colombia S.A.S para la exportación de pulpa de limón al mercado holandés

OpenAIRE

Piedrahita Bravo, Carlos Hernán; Marín Ríos, Esteban

2012-01-01

El presente documento ofrece una guía logística y análisis financiero para las pequeñas y medianas empresas (PyMES) de Colombia que deseen exportar pulpa de limón al mercado Europeo. Para el desarrollo de este trabajo se ha tomado el caso de la micro empresa COMERFRUTAS de Colombia S.A.S. (productora de pulpa de limón) y se ha realizado un estudio de competitividad de puertos, agentes de carga tanto terrestre como marítimos para dar las bases necesarias de exportación a las PyMES colombianas ...

A model of the dose rate calculation for a spent fuel storage structure by Monte Carlo method using the modulated code system SCALE 4.4a

International Nuclear Information System (INIS)

Pantazi, D.; Mateescu, S.; Stanciu, M.; Mete, M.

2001-01-01

The modulated code system SCALE is used to perform a standardized shielding analysis for any facility containing spent fuel: handling devices, transport cask, intermediate and final storage facility. The neutron and gamma sources as well as the dose rates can be obtained using either discrete-ordinates or Monte Carlo methods. The shielding analysis control modules (SAS1, SAS2H and SAS4) provide a general procedure for cross-section preparation, fuel depletion/decay calculation and general onedimensional or multi-dimensional shielding analysis. The module SAS4 used in the analysis presented in this paper, is a three-dimensional Monte Carlo shielding analysis module, which uses an automated biasing procedure specialized for a nuclear fuel transport or storage container. The Spent Fuel Interim Storage Facility in our country is projected to be a parallelepiped concrete monolithic module, consisting of an external reinforced concrete structure with vertical storage cylinders (pits) arranged in a rectangular array. A pit is filled with sealed cylindrical baskets of stainless steel arranged in a stack, and with each basket containing spent fuel bundles in vertical position. The pit is closed with a concrete plug. The cylindrical geometry model is used in the shielding evaluation for a spent fuel storage structure (pit), and only the active parts of the superposed bundles is considered. The dose rates have been calculated in both the axial and radial directions using SAS4.(author)

How to Deal with Interval-Censored Data Practically while Assessing the Progression-Free Survival: A Step-by-Step Guide Using SAS and R Software.

Science.gov (United States)

Dugué, Audrey Emmanuelle; Pulido, Marina; Chabaud, Sylvie; Belin, Lisa; Gal, Jocelyn

2016-12-01

We describe how to estimate progression-free survival while dealing with interval-censored data in the setting of clinical trials in oncology. Three procedures with SAS and R statistical software are described: one allowing for a nonparametric maximum likelihood estimation of the survival curve using the EM-ICM (Expectation and Maximization-Iterative Convex Minorant) algorithm as described by Wellner and Zhan in 1997; a sensitivity analysis procedure in which the progression time is assigned (i) at the midpoint, (ii) at the upper limit (reflecting the standard analysis when the progression time is assigned at the first radiologic exam showing progressive disease), or (iii) at the lower limit of the censoring interval; and finally, two multiple imputations are described considering a uniform or the nonparametric maximum likelihood estimation (NPMLE) distribution. Clin Cancer Res; 22(23); 5629-35. ©2016 AACR. ©2016 American Association for Cancer Research.

[The legal framework of the code of ethics for nurses].

Science.gov (United States)

Doutriaux, Yves

2017-09-01

As with all professions with its own order, nurses now have a code of ethics written by the Order's elected leaders. These leaders oversee its application for the benefit of patients and professionals, notably when a complaint is made. The code reconciles the interests of patients and public health care with the competition law. The numerous innovations which it has introduced are beneficial to nurses employed in the public and private sectors as well as freelance nurses. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

The Evaluation of Bivariate Mixed Models in Meta-analyses of Diagnostic Accuracy Studies with SAS, Stata and R.

Science.gov (United States)

Vogelgesang, Felicitas; Schlattmann, Peter; Dewey, Marc

2018-05-01

Meta-analyses require a thoroughly planned procedure to obtain unbiased overall estimates. From a statistical point of view not only model selection but also model implementation in the software affects the results. The present simulation study investigates the accuracy of different implementations of general and generalized bivariate mixed models in SAS (using proc mixed, proc glimmix and proc nlmixed), Stata (using gllamm, xtmelogit and midas) and R (using reitsma from package mada and glmer from package lme4). Both models incorporate the relationship between sensitivity and specificity - the two outcomes of interest in meta-analyses of diagnostic accuracy studies - utilizing random effects. Model performance is compared in nine meta-analytic scenarios reflecting the combination of three sizes for meta-analyses (89, 30 and 10 studies) with three pairs of sensitivity/specificity values (97%/87%; 85%/75%; 90%/93%). The evaluation of accuracy in terms of bias, standard error and mean squared error reveals that all implementations of the generalized bivariate model calculate sensitivity and specificity estimates with deviations less than two percentage points. proc mixed which together with reitsma implements the general bivariate mixed model proposed by Reitsma rather shows convergence problems. The random effect parameters are in general underestimated. This study shows that flexibility and simplicity of model specification together with convergence robustness should influence implementation recommendations, as the accuracy in terms of bias was acceptable in all implementations using the generalized approach. Schattauer GmbH.

Porovnání statistických programových systémů SPSS, STATISTICA a SAS z hlediska jejich možností při analýze kategoriálních dat

OpenAIRE

Torboněnko, Natalja

2009-01-01

The purpose of this bachelor thesis is to compare three statistical software packages when applied to analysis of categorical data. These packages are SPSS, STATISTICA , and SAS Enterprise Guide. They provide a wide variety of statistical and graphical techniques, and enable users to obtain the results of statistical procedures, without requiring programming. The comparison between these packages were based upon some features such as data input, capability to define missing values, value labe...

Multi-dimensional Code Development for Safety Analysis of LMR

International Nuclear Information System (INIS)

Ha, K. S.; Jeong, H. Y.; Kwon, Y. M.; Lee, Y. B.

2006-08-01

A liquid metal reactor loaded a metallic fuel has the inherent safety mechanism due to the several negative reactivity feedback. Although this feature demonstrated through experiments in the EBR-II, any of the computer programs until now did not exactly analyze it because of the complexity of the reactivity feedback mechanism. A multi-dimensional detail program was developed through the International Nuclear Energy Research Initiative(INERI) from 2003 to 2005. This report includes the numerical coupling the multi-dimensional program and SSC-K code which is used to the safety analysis of liquid metal reactors in KAERI. The coupled code has been proved by comparing the analysis results using the code with the results using SAS-SASSYS code of ANL for the UTOP, ULOF, and ULOHS applied to the safety analysis for KALIMER-150

An analysis of the number of parking bays and checkout counters for a supermarket using SAS simulation studio

Science.gov (United States)

Kar, Leow Soo

2014-07-01

Two important factors that influence customer satisfaction in large supermarkets or hypermarkets are adequate parking facilities and short waiting times at the checkout counters. This paper describes the simulation analysis of a large supermarket to determine the optimal levels of these two factors. SAS Simulation Studio is used to model a large supermarket in a shopping mall with car park facility. In order to make the simulation model more realistic, a number of complexities are introduced into the model. For example, arrival patterns of customers vary with the time of the day (morning, afternoon and evening) and with the day of the week (weekdays or weekends), the transport mode of arriving customers (by car or other means), the mode of payment (cash or credit card), customer shopping pattern (leisurely, normal, exact) or choice of checkout counters (normal or express). In this study, we focus on 2 important components of the simulation model, namely the parking area, the normal and express checkout counters. The parking area is modeled using a Resource Pool block where one resource unit represents one parking bay. A customer arriving by car seizes a unit of the resource from the Pool block (parks car) and only releases it when he exits the system. Cars arriving when the Resource Pool is empty (no more parking bays) leave without entering the system. The normal and express checkouts are represented by Server blocks with appropriate service time distributions. As a case study, a supermarket in a shopping mall with a limited number of parking bays in Bangsar was chosen for this research. Empirical data on arrival patterns, arrival modes, payment modes, shopping patterns, service times of the checkout counters were collected and analyzed to validate the model. Sensitivity analysis was also performed with different simulation scenarios to identify the parameters for the optimal number the parking spaces and checkout counters.

Modeling nest-survival data: a comparison of recently developed methods that can be implemented in MARK and SAS

Directory of Open Access Journals (Sweden)

Rotella, J. J.

2004-06-01

Full Text Available Estimating nest success and evaluating factors potentially related to the survival rates of nests are key aspects of many studies of avian populations. A strong interest in nest success has led to a rich literature detailing a variety of estimation methods for this vital rate. In recent years, modeling approaches have undergone especially rapid development. Despite these advances, most researchers still employ Mayfield’s ad-hoc method (Mayfield, 1961 or, in some cases, the maximum-likelihood estimator of Johnson (1979 and Bart & Robson (1982. Such methods permit analyses of stratified data but do not allow for more complex and realistic models of nest survival rate that include covariates that vary by individual, nest age, time, etc. and that may be continuous or categorical. Methods that allow researchers to rigorously assess the importance of a variety of biological factors that might affect nest survival rates can now be readily implemented in Program MARK and in SAS’s Proc GENMOD and Proc NLMIXED. Accordingly, use of Mayfield’s estimator without first evaluating the need for more complex models of nest survival rate cannot be justified. With the goal of increasing the use of more flexible methods, we first describe the likelihood used for these models and then consider the question of what the effective sample size is for computation of AICc. Next, we consider the advantages and disadvantages of these different programs in terms of ease of data input and model construction; utility/flexibility of generated estimates and predictions; ease of model selection; and ability to estimate variance components. An example data set is then analyzed using both MARK and SAS to demonstrate implementation of the methods with various models that contain nest-, group- (or block-, and time-specific covariates. Finally, we discuss improvements that would, if they became available, promote a better general understanding of nest survival rates.

Laborsalud S.A.S.

OpenAIRE

2013-01-01

Crear una empresa prestadora de servicios integrales en salud ocupacional basados en la legislación vigente y enfocada a la satisfacción de las necesidades de los clientes, que brinde un valor agregado como expertos con un sistema de resultados en línea a través de su página web y amplio portafolio que integre los requerimientos en materia de salud ocupacional y seguridad industrial de las empresas.

Modelo para la definición e implementación de procesos de gobierno de tecnologías de la información aplicado a CENIT Transporte y Logística de Hidrocarburos S.A.S.

OpenAIRE

Páez Ruiz, Andrea Paola; Vivas Hernández, Fredy

2016-01-01

El crecimiento que ha venido presentando CENIT Transporte y logística de hidrocarburos S.A.S. ha conducido a su área de tecnología a revisar los procesos tecnológicos con los que apoya a todas las áreas de negocio para el logro de la estrategia empresarial. Para poder cumplir con esta promesa de valor hacia la organización, el área de tecnología bajo un marco de trabajo reconocido debe analizar, definir, estructurar e implementar formalmente sus procesos y de esta manera también cumplirá con ...

Analyses of PWR spent fuel composition using SCALE and SWAT code systems to find correction factors for criticality safety applications adopting burnup credit

Energy Technology Data Exchange (ETDEWEB)

Shin, Hee Sung; Suyama, Kenya; Mochizuki, Hiroki; Okuno, Hiroshi; Nomura, Yasushi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

2001-01-01

The isotopic composition calculations were performed for 26 spent fuel samples from the Obrigheim PWR reactor and 55 spent fuel samples from 7 PWR reactors using the SAS2H module of the SCALE4.4 code system with 27, 44 and 238 group cross-section libraries and the SWAT code system with the 107 group cross-section library. For the analyses of samples from the Obrigheim PWR reactor, geometrical models were constructed for each of SCALE4.4/SAS2H and SWAT. For the analyses of samples from 7 PWR reactors, the geometrical model already adopted in the SCALE/SAS2H was directly converted to the model of SWAT. The four kinds of calculation results were compared with the measured data. For convenience, the ratio of the measured to calculated values was used as a parameter. When the ratio is less than unity, the calculation overestimates the measurement, and the ratio becomes closer to unity, they have a better agreement. For many important nuclides for burnup credit criticality safety evaluation, the four methods applied in this study showed good coincidence with measurements in general. More precise observations showed, however: (1) Less unity ratios were found for Pu-239 and -241 for selected 16 samples out of the 26 samples from the Obrigheim reactor (10 samples were deselected because their burnups were measured with Cs-137 non-destructive method, less reliable than Nd-148 method the rest 16 samples were measured with); (2) Larger than unity ratios were found for Am-241 and Cm-242 for both the 16 and 55 samples; (3) Larger than unity ratios were found for Sm-149 for the 55 samples; (4) SWAT was generally accompanied by larger ratios than those of SAS2H with some exceptions. Based on the measured-to-calculated ratios for 71 samples of a combined set in which 16 selected samples and 55 samples were included, the correction factors that should be multiplied to the calculated isotopic compositions were generated for a conservative estimate of the neutron multiplication factor

[The code of ethics for nurses, history and perspectives].

Science.gov (United States)

de Kerguenec, Yann

2017-09-01

The French decree of 25 November 2016 relating to the code of ethics for nurses reinforces the principles guiding their missions and the corresponding responsibilities. It is the fruit of a collaboration between nurses from all backgrounds heavily involved in the Order. Imbued with the nursing spirit, reflecting the sensitivities and concerns of professionals, it is a unique project and, in every regard, quite remarkable, as it has been produced by a profession which is often reluctant to put pen to paper to express its vision of health. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

The scale analysis sequence for LWR fuel depletion

International Nuclear Information System (INIS)

Hermann, O.W.; Parks, C.V.

1991-01-01

The SCALE (Standardized Computer Analyses for Licensing Evaluation) code system is used extensively to perform away-from-reactor safety analysis (particularly criticality safety, shielding, heat transfer analyses) for spent light water reactor (LWR) fuel. Spent fuel characteristics such as radiation sources, heat generation sources, and isotopic concentrations can be computed within SCALE using the SAS2 control module. A significantly enhanced version of the SAS2 control module, which is denoted as SAS2H, has been made available with the release of SCALE-4. For each time-dependent fuel composition, SAS2H performs one-dimensional (1-D) neutron transport analyses (via XSDRNPM-S) of the reactor fuel assembly using a two-part procedure with two separate unit-cell-lattice models. The cross sections derived from a transport analysis at each time step are used in a point-depletion computation (via ORIGEN-S) that produces the burnup-dependent fuel composition to be used in the next spectral calculation. A final ORIGEN-S case is used to perform the complete depletion/decay analysis using the burnup-dependent cross sections. The techniques used by SAS2H and two recent applications of the code are reviewed in this paper. 17 refs., 5 figs., 5 tabs

Krāsas un skaņas sintēzes metodes izmantošanas iespējas gleznošanas nodarbībās mākslas skolā

OpenAIRE

Zilberte, Baiba

2007-01-01

Viens no vizuālās mākslas izglītības mērķiem ir nodrošināt vizuālās mākslas valodas apguvi un attīstīt skolēnu izpratni par procesiem mūsdienu mākslā un mākslas komunikācijā. Mērķi nav iespējams sasniegt, ja mākslas izglītībā netiek iekļauts mūsdienu vizuālās mākslas gan lokālais, gan starptautiskais konteksts. Krāsas un skaņas sintēze kā metode var tikt pielietota mākslas pedagoģijā, lai veidotu izpratni par mūsdienu vizuālo mākslu, attīstītu skolēnu uztveri un domāšanu, paplašinātu vizuālo ...

Message passing vs. shared address space on a cluster of SMPs

International Nuclear Information System (INIS)

Shan, Hongzhang; Singh, Jaswinder Pal; Oliker, Leonid; Biswas, Rupak

2001-01-01

The emergence of scalable computer architectures using clusters of PCs or PC-SMPs with commodity networking has made them attractive platforms for high-end scientific computing. Currently, message passing (MP) and shared address space (SAS) are the two leading programming paradigms for these systems. MP has been standardized with MPI, and is the most common and mature parallel programming approach. However, MP code development can be extremely difficult, especially for irregularly structured computations. SAS offers substantial ease of programming, but may suffer from performance limitations due to poor spatial locality and high protocol overhead. In this paper, they compare the performance of and programming effort required for six applications under both programming models on a 32-CPU PC-SMP cluster. Our application suite consists of codes that typically do not exhibit scalable performance under shared-memory programming due to their high communication-to-computation ratios and complex communication patterns. Results indicate that SAS can achieve about half the parallel efficiency of MPI for most of the applications; however, on certain classes of problems, SAS performance is competitive with MPI

LIMBO computer code for analyzing coolant-voiding dynamics in LMFBR safety tests

International Nuclear Information System (INIS)

Bordner, G.L.

1979-10-01

The LIMBO (liquid metal boiling) code for the analysis of two-phase flow phenomena in an LMFBR reactor coolant channel is presented. The code uses a nonequilibrium, annular, two-phase flow model, which allows for slip between the phases. Furthermore, the model is intended to be valid for both quasi-steady boiling and rapid coolant voiding of the channel. The code was developed primarily for the prediction of, and the posttest analysis of, coolant-voiding behavior in the SLSF P-series in-pile safety test experiments. The program was conceived to be simple, efficient, and easy to use. It is particularly suited for parametric studies requiring many computer runs and for the evaluation of the effects of model or correlation changes that require modification of the computer program. The LIMBO code, of course, lacks the sophistication and model detail of the reactor safety codes, such as SAS, and is therefore intended to compliment these safety codes

Multilevel models applications using SAS

CERN Document Server

Wang, Jichuan; Fisher, James F

2011-01-01

This book covers a broad range of topics about multilevel modeling. The goal is to help readers to understand the basic concepts, theoretical frameworks, and application methods of multilevel modeling. It is at a level also accessible to non-mathematicians, focusing on the methods and applications of various multilevel models and using the widely used statistical software SAS®. Examples are drawn from analysis of real-world research data.

Speech Acts During Friends' and Non-friends' Spontaneous Conversations in Preschool Dyads with High-Functioning Autism Spectrum Disorder versus Typical Development.

Science.gov (United States)

Bauminger-Zviely, Nirit; Golan-Itshaky, Adi; Tubul-Lavy, Gila

2017-05-01

In this study, we videotaped two 10-min. free-play interactions and coded speech acts (SAs) in peer talk of 51 preschoolers (21 ASD, 30 typical), interacting with friend versus non-friend partners. Groups were matched for maternal education, IQ (verbal/nonverbal), and CA. We compared SAs by group (ASD/typical), by partner's friendship status (friend/non-friend), and by partner's disability status. Main results yielded a higher amount and diversity of SAs in the typical than the ASD group (mainly in assertive acts, organizational devices, object-dubbing, and pretend-play); yet, those categories, among others, showed better performance with friends versus non-friends. Overall, a more nuanced perception of the pragmatic deficit in ASD should be adopted, highlighting friendship as an important context for children's development of SAs.

Development of standardized laboratory methods and quality processes for a phase III study of the RTS, S/AS01 candidate malaria vaccine

Directory of Open Access Journals (Sweden)

Carter Terrell

2011-08-01

Full Text Available Abstract Background A pivotal phase III study of the RTS,S/AS01 malaria candidate vaccine is ongoing in several research centres across Africa. The development and establishment of quality systems was a requirement for trial conduct to meet international regulatory standards, as well as providing an important capacity strengthening opportunity for study centres. Methods Standardized laboratory methods and quality assurance processes were implemented at each of the study centres, facilitated by funding partners. Results A robust protocol for determination of parasite density based on actual blood cell counts was set up in accordance with World Health Organization recommendations. Automated equipment including haematology and biochemistry analyzers were put in place with standard methods for bedside testing of glycaemia, base excess and lactacidaemia. Facilities for X-rays and basic microbiology testing were also provided or upgraded alongside health care infrastructure in some centres. External quality assurance assessment of all major laboratory methods was established and method qualification by each laboratory demonstrated. The resulting capacity strengthening has ensured laboratory evaluations are conducted locally to the high standards required in clinical trials. Conclusion Major efforts by study centres, together with support from collaborating parties, have allowed standardized methods and robust quality assurance processes to be put in place for the phase III evaluation of the RTS, S/AS01 malaria candidate vaccine. Extensive training programmes, coupled with continuous commitment from research centre staff, have been the key elements behind the successful implementation of quality processes. It is expected these activities will culminate in healthcare benefits for the subjects and communities participating in these trials. Trial registration Clinicaltrials.gov NCT00866619

[Code of ethics for nurses and territory hospital group].

Science.gov (United States)

Danan, Jane-Laure; Giraud-Rochon, François

2017-09-01

The publication of the decree relating to the code of ethics for nurses means that the State is producing a text for all nursing professionals, whatever their sector or their mode of practice. However, faced with the standardisation of nursing procedures, the production of a new standard by a government is not a neutral issue. On the one hand, it could constitute a reinforcement of the professional credibility of this corporation; on the other this text becomes enforceable on all nurses and employers. Within a territory hospital group, this reflection must form part of nursing and managerial practices and the relationships with the hospital administration. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

SEALER: a very small lead cooled fast reactor for commercial energy production in off-grid communities

Energy Technology Data Exchange (ETDEWEB)

Wallenius, J., E-mail: janne@leadcold.com [LeadCold Reactors, Dalgatan 3C, Marsta (Sweden); Bortot, S., E-mail: sara.bortot@psi.ch [Paul Scherrer Inst., Villigen (Switzerland)

2014-07-01

SEALER (Swedish Advanced Lead Reactor) is a small lead cooled fast reactor operating on 20% enriched UO{sub 2} fuel. It is designed for commercial production of electricity and heat in the Canadian arctic. In this paper, we present an updated set of reactivity coefficients for the SEALER core, used in simulations of un-protected transients such as control-rod withdrawal, and loss of flow. The analysis is carried out using the SAS4A/SASSYS-1 (SAS) system code developed by ANL and the BELLA multi-point dynamics code developed by KTH and PSI. (author)

Severe accidents and ESFR design issues

International Nuclear Information System (INIS)

Rineiski, A.

2013-01-01

Current SFR studies in Germany: ⇒ In support of European SFR studies, mainly on safety and safety-related (design optimization) issues; ⇒ ADS and SFR as main options for spent fuel management in studies on the possibility of P&T; ⇒ ESFR-type designs studied recently; ⇒ ASTRID-type designs to be studied in the future; ⇒ Particular area: modeling of severe accidents with SAS4A/SAS-SFR and SIMMER codes

Use of SAS in the IDB

International Nuclear Information System (INIS)

Morrison, G.W.; Notz, K.J.; Mastal, E.F.; Trice, V.G.

1984-01-01

The Integrated Data Base (IDB) Program provides official US Department of Energy (DOE) data on spent fuel and radioactive waste inventories, projections, and characteristics. This information is provided through the cooperative efforts of the IDB Program and DOE lead offices, lead sites, major programs, and generator sites. The program is entering its fifth yeaar, and major accomplishments are summarized in three broad areas: (1) the annual inventory report, including ORIGEN2 applications and a Quality Assurance (QA) plan; (2) the summary data file and direct user access; and (3) data processing methodology and support to other programs. Plans for future work in these areas are outlined briefly, including increased utilization of personal computers. Some examples of spent fuel data are given in terms of projected quantities for two growth scenarios, burnup and age profile of the existing inventory, and the approximate specific thermal power relative to high-level waste (HLW) from various sources. 2 references, 3 figures

SAS-Based Studies of Protein Fibrillation

DEFF Research Database (Denmark)

Marasini, Carlotta; Vestergaard, Bente

2017-01-01

Protein fibrillation is associated with a number of fatal amyloid diseases (e.g. Alzheimer's and Parkinson's diseases). From a structural point of view, the aggregation process starts from an ensemble of native states that convert into transiently formed oligomers, higher order assemblies and pro...... and highlight existing reports, exemplifying the wealth of information that can be derived from the method....

Plan de negocios para la constitución de una empresa consultora que preste los servicios de asesoría para la planeación estratégica de organizaciones y la gerencia de proyectos implementando la metodología PMI - JYJ Project Offices S.A.S.

OpenAIRE

Contreras Delgadillo, Yair Esteban; Noriega Silva, Juan Carlos; Benítez Granados, John

2012-01-01

El presente documento describe el plan de negocio para la creación de una empresa de consultoría que asesore, forme las capacidades humanas y acompañe a medianas y grandes empresas de los sectores de Hidrocarburos (Petróleo), Construcción, Obras civiles y Telecomunicaciones, en la gestión de proyectos, creación de Oficinas de Proyectos con enfoque PMI y planeación estratégica. Esta empresa cuya razón social será JYJ Project Offices S.A.S., ofrecerá sus servicios a empresas localizadas en la ...

U.S. Sodium Fast Reactor Codes and Methods: Current Capabilities and Path Forward

Energy Technology Data Exchange (ETDEWEB)

Brunett, A. J.; Fanning, T. H.

2017-06-26

The United States has extensive experience with the design, construction, and operation of sodium cooled fast reactors (SFRs) over the last six decades. Despite the closure of various facilities, the U.S. continues to dedicate research and development (R&D) efforts to the design of innovative experimental, prototype, and commercial facilities. Accordingly, in support of the rich operating history and ongoing design efforts, the U.S. has been developing and maintaining a series of tools with capabilities that envelope all facets of SFR design and safety analyses. This paper provides an overview of the current U.S. SFR analysis toolset, including codes such as SAS4A/SASSYS-1, MC2-3, SE2-ANL, PERSENT, NUBOW-3D, and LIFE-METAL, as well as the higher-fidelity tools (e.g. PROTEUS) being integrated into the toolset. Current capabilities of the codes are described and key ongoing development efforts are highlighted for some codes.

Orthopedics coding and funding.

Science.gov (United States)

Baron, S; Duclos, C; Thoreux, P

2014-02-01

The French tarification à l'activité (T2A) prospective payment system is a financial system in which a health-care institution's resources are based on performed activity. Activity is described via the PMSI medical information system (programme de médicalisation du système d'information). The PMSI classifies hospital cases by clinical and economic categories known as diagnosis-related groups (DRG), each with an associated price tag. Coding a hospital case involves giving as realistic a description as possible so as to categorize it in the right DRG and thus ensure appropriate payment. For this, it is essential to understand what determines the pricing of inpatient stay: namely, the code for the surgical procedure, the patient's principal diagnosis (reason for admission), codes for comorbidities (everything that adds to management burden), and the management of the length of inpatient stay. The PMSI is used to analyze the institution's activity and dynamism: change on previous year, relation to target, and comparison with competing institutions based on indicators such as the mean length of stay performance indicator (MLS PI). The T2A system improves overall care efficiency. Quality of care, however, is not presently taken account of in the payment made to the institution, as there are no indicators for this; work needs to be done on this topic. Copyright © 2014. Published by Elsevier Masson SAS.

DRAGON analysis of MOX fueled VVER cell benchmarks

International Nuclear Information System (INIS)

Marleau, G.; Foissac, F.

2002-01-01

The computational unit-cell benchmarks problems for LEU and MOX fueled VVER-1000 ('water-water energetic reactor') have been analyzed using the code DRAGON with ENDF/B-V and ENDF/B-VI based WIMS-AECL cross section libraries. The results obtained were compared with those generated using the SAS2H module of the SCALE-4.3 computational code system and with the code HELIOS. Good agreements between DRAGON and HELIOS were obtained when the ENDF/B-VI based library was considered while the ENDF/B-V DRAGON results were generally closer to those obtained using SAS2H. This study was useful for the verification of the DRAGON code and confirms that HELIOS and DRAGON have a similar behavior when compatible cross sections library are used. (author)

Sequence Classification: 894385 [

Lifescience Database Archive (English)

Full Text Available t of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates tra...nscriptional silencing; stimulates Sas2p HAT activity; Sas5p || http://www.ncbi.nlm.nih.gov/protein/6324787 ...

Status of SFR Codes and Methods QA Implementation

Energy Technology Data Exchange (ETDEWEB)

Brunett, Acacia J. [Argonne National Lab. (ANL), Argonne, IL (United States); Briggs, Laural L. [Argonne National Lab. (ANL), Argonne, IL (United States); Fanning, Thomas H. [Argonne National Lab. (ANL), Argonne, IL (United States)

2017-01-31

This report details development of the SAS4A/SASSYS-1 SQA Program and describes the initial stages of Program implementation planning. The provisional Program structure, which is largely focused on the establishment of compliant SQA documentation, is outlined in detail, and Program compliance with the appropriate SQA requirements is highlighted. Additional program activities, such as improvements to testing methods and Program surveillance, are also described in this report. Given that the programmatic resources currently granted to development of the SAS4A/SASSYS-1 SQA Program framework are not sufficient to adequately address all SQA requirements (e.g. NQA-1, NUREG/BR-0167, etc.), this report also provides an overview of the gaps that remain the SQA program, and highlights recommendations on a path forward to resolution of these issues. One key finding of this effort is the identification of the need for an SQA program sustainable over multiple years within DOE annual R&D funding constraints.

An assessment of core wide coherency effects in the multichannel modeling of the initiating phase of a severe accident in a sodium fast reactor

International Nuclear Information System (INIS)

Guyot, M.; Gubernatis, P.; Suteau, C.; Le Tellier, R.; Lecerf, J.

2014-01-01

To consolidate the safety assessment for liquid-metal fast breeder reactors (LMFBRs), hypothetical core disruptive accident (HCDA) sequences have been extensively studied over the past decades. Numerous analyses of the so called initiating phase (or primary phase) of a HCDA have been made with the safety analysis system code SAS4A. The SAS4A accident analysis code requires that subassemblies or groups of subassemblies be represented together as independent channels. For simulating a severe accident sequence, a subassembly-to-channel assignment procedure has to be implemented to produce the consistent SAS4A input decks. Generally, one uses imposed criteria over relevant reactor parameters to determine the subassembly to- channel arrangement. The multiple-assembly-per-channel approach introduces core wide coherency effects, which can affect the reactivity balance and therefore the overall accident development. In this paper, a subassembly-to channel assignment procedure based on the subassembly power-to-flow ratio is presented and implemented to generate the SAS4A input decks over a range of parameter values. The corresponding SAS4A calculations have been performed on a large LMFBR. The purpose of the present series of calculations is to investigate the magnitude of errors encountered in the analysis of the initiating phase related to the subassembly-to-channel arrangement selection, by comparison with a one-subassembly-per-channel reference solution. It appears that a refinement in the channel arrangement substantially reduces core wide coherency effects. Analysis of the calculations also suggests that an accurate representation of the scenario requires the number of channels to be on approximately the same order of magnitude as the total number of subassemblies. Numerical results are examined to provide the reader with quantitative measurements of bias related to subassembly to- channel arrangement. (authors)

Development and application of the CRAMP code for fast reactor core assessment

International Nuclear Information System (INIS)

Duthie, J.C.

1987-01-01

During reactor operation, the components in the core of a fast reactor suffer neutron induced voidage swelling. This causes dilation and, in conjunction with thermal and flux gradients, bowing of the core subassemblies (S/As). These effects lead to contacts between adjacent S/As. It is necessary to be able to calculate the displacements and loads generated in the core to ensure that monitoring instruments and absorber rods function satisfactorily, that wrapper stress limits are not reached and that refuelling can be carried out reliably. Although the behaviour of each individual S/A can be respresented to a good approximation as being linear, the behaviour of the whole core is a large, non-linear problem. The computer programm CRAMP, which was written to solve this problem, is described in this paper. (orig./GL)

The role of internal and external control for mitigating or preventing LMR accidents

International Nuclear Information System (INIS)

Waltar, A.E.; Padilla, A.; Seeman, S.E.

1987-01-01

For the safety assessment of LMFBRs, much effort has been devoted to the analyses of LOF accident sequences with an emphasis on initiating-phase (IP) energetics (LOF-d-TOP event). Important knowledge and experiences on the IP energetics have been accumulated through reactor studies and in-pile experiment analyses, typically for the CABRI experiments. The present paper summarises the current understanding of key phenomenology relevant to the IP energetics based on the CABRI experiment analyses and the validation study for the PAPAS-2S, SAS3D and SAS4A codes. (author)

Characteristic Risk Factors Associated with Planned versus Impulsive Suicide Attempters.

Science.gov (United States)

Kim, Jaeha; Lee, Kang-Sook; Kim, Dai Jin; Hong, Seung-Chul; Choi, Kyoung Ho; Oh, Youngmin; Wang, Sheng-Min; Lee, Hae-Kook; Kweon, Yong-Sil; Lee, Chung Tai; Lee, Kyoung-Uk

2015-12-31

The present study aimed to investigate predictors for planned suicide attempters. This study included 1,003 patients who attempted suicide and visited emergency department. They were divided into two groups, planned suicide attempters (SAs; n=133 [13.3%]) and impulsive SAs (n=870, [86.7%]), and the demographic variables, clinical characteristics, factors related to suicide, and psychiatric resources of the groups were compared. Major depressive disorder and substance use disorders were more common among planned SAs than among impulsive SAs. Additionally, the planned SAs were older, more likely to be divorced, separated or widowed, and more likely to have comorbid medical illnesses, severe depression, higher suicidality, and self-blaming tendencies than the impulsive SAs. Financial problems and physical illnesses were more common in planned SAs but interpersonal conflicts were more frequent in impulsive SAs. Planned SAs had fewer previous suicide attempts but these were more serious suicide attempts. The presence of the hope to die, a written will, and suicidal ideation of a repetitive, intense, and continuous nature were predictive of planned SAs. The present findings demonstrated that planned SAs had more severe psychopathology and medical illnesses than impulsive SAs. Therefore, screening for depression, substance use disorders, and suicidal plans among old and medically ill patients may be important for preventing suicide attempts.

USING SAS ENTERPRISE GUIDE SOFTWARE IN CLASSIFICATION

OpenAIRE

Ana Maria Mihaela IORDACHE

2011-01-01

Data mining, also known as "discovery knowledge in large databases "is a modern and powerful information technology and communications tool that can be used to extract useful information but still unknown. This automates the process of discovery some relations and mixtures from the raw data and founded results could be incorporated into an automated decision support. This paper aims to present and perform the classification of European Union countries based on the social indicators calculated...

SAS Institute pre-sales internship : internship report

OpenAIRE

António, Bruno Alexandre Zeverino

2017-01-01

The present document describes the work developed during the six months internship at SAS® Institute Inc.. During the internship, the intern provided support to the Pre-Sales department by integrating the analytic team. The intern received access to an extensive selection of courses designed to introduce the core technologies and present the analytical tools developed by SAS®. He was later integrated in a team working in a proof of concept dedicated to showcase the forecast capability of SAS®...

Statistical analysis of medical data using SAS

CERN Document Server

Der, Geoff

2005-01-01

An Introduction to SASDescribing and Summarizing DataBasic InferenceScatterplots Correlation: Simple Regression and SmoothingAnalysis of Variance and CovarianceMultiple RegressionLogistic RegressionThe Generalized Linear ModelGeneralized Additive ModelsNonlinear Regression ModelsThe Analysis of Longitudinal Data IThe Analysis of Longitudinal Data II: Models for Normal Response VariablesThe Analysis of Longitudinal Data III: Non-Normal ResponseSurvival AnalysisAnalysis Multivariate Date: Principal Components and Cluster AnalysisReferences

78 FR 73009 - Takes of Marine Mammals Incidental to Specified Activities; U.S. Navy Training and Testing...

Science.gov (United States)

2013-12-04

.... Synthetic Aperture Sonars SAS1 MF SAS systems. (SAS): Sonars in which SAS2 HF SAS systems. active acoustic... sails are not dedicated ASW events and involve multiple warfare areas. Non-Impulsive ASW for Composite... Grenades. anti-swimmer grenades to defend against hostile divers (e.g., Visit, Board, Search, and Seizure...

Coded aperture detector for high precision gamma-ray burst source locations

International Nuclear Information System (INIS)

Helmken, H.; Gorenstein, P.

1977-01-01

Coded aperture collimators in conjunction with position-sensitive detectors are very useful in the study of transient phenomenon because they combine broad field of view, high sensitivity, and an ability for precise source locations. Since the preceeding conference, a series of computer simulations of various detector designs have been carried out with the aid of a CDC 6400. Particular emphasis was placed on the development of a unit consisting of a one-dimensional random or periodic collimator in conjunction with a two-dimensional position-sensitive Xenon proportional counter. A configuration involving four of these units has been incorporated into the preliminary design study of the Transient Explorer (ATREX) satellite and are applicable to any SAS or HEAO type satellite mission. Results of this study, including detector response, fields of view, and source location precision, will be presented

Program improvement and applications; Programmpflege und Anwendungen

Energy Technology Data Exchange (ETDEWEB)

Hink, M.; Imke, U.; Pfrang, W.; Porscha, B.; Struwe, D.; Zimmerer, W.; Allan, P.

1995-08-01

An account is given about further improvements of the SAS4A-Ref. 94.R0 version of the HCDA code. They concern in particular the DEFORM fuel rod deformation module. For a validation of the new code version, various CABRI experiments have been calculated, especially tests with high burnup fuel rods. Progress was shown to be achieved, but the precise timing and location of the observed fuel failures is still hard to calculate. The work was performed in close cooperation with partners in France, Britain, and Japan. An important application concerns the CAPRA project of a reactor for actinide burning. Its behavior under ULOF conditions was analyzed using the improved SAS4A Ref. 94 R0 code. The core design turned out to tend toward a long-term coolable configuration even more so than the EFR core design would do in an ULOF. (orig.)

Program improvement and applications

International Nuclear Information System (INIS)

Hink, M.; Imke, U.; Pfrang, W.; Porscha, B.; Struwe, D.; Zimmerer, W.; Allan, P.

1995-01-01

An account is given about further improvements of the SAS4A-Ref. 94.R0 version of the HCDA code. They concern in particular the DEFORM fuel rod deformation module. For a validation of the new code version, various CABRI experiments have been calculated, especially tests with high burnup fuel rods. Progress was shown to be achieved, but the precise timing and location of the observed fuel failures is still hard to calculate. The work was performed in close cooperation with partners in France, Britain, and Japan. An important application concerns the CAPRA project of a reactor for actinide burning. Its behavior under ULOF conditions was analyzed using the improved SAS4A Ref. 94 R0 code. The core design turned out to tend toward a long-term coolable configuration even more so than the EFR core design would do in an ULOF. (orig.)

Specialty and Associate Specialist doctors: still the dependable backbone of genitourinary medicine.

Science.gov (United States)

Lee, J D; Carlin, E M; Robinson, A

2013-05-01

Workforce planning is an inexact science. Specialty and Associate Specialist (SAS) doctors are rarely included in workforce analyses. Past studies have shown that SAS doctors are significant contributors to the work in genitourinary (GU) medicine clinics. This survey confirms the large amount of clinical work undertaken by SAS doctors. It appears that 51% of SAS doctors in GU plan to retire in the next 15 years and it is uncertain what effect the 2008 SAS contract will have on SAS recruitment. This information should be taken into consideration in future GUM workforce planning.

Residual veterinary antibiotics in pig excreta after oral administration of sulfonamides.

Science.gov (United States)

Qiu, Jinrong; Zhao, Tao; Liu, Qingyun; He, Jinhua; He, Dechun; Wu, Genyi; Li, Yongtao; Jiang, Chengai; Xu, Zhencheng

2016-04-01

Sulfonamides (SAs) are applied widely as feed additives in the farming of livestock and poultry. It can lead to the excretion of large amounts of SAs in manure and result in persistent environmental pollution. We evaluated the fate of four SAs, sulfamerazine (SM1), sulfachloropyridazine (SCP), sulfadimoxine (SDM') and sulfaquinoxaline (SQ), from oral administration to excretion in urine and feces in pigs. The four SAs were added to homemade feed to make them reach the required concentration gradient, which were 0, 50 and 100 mg/kg (low, normal and high concentrations, respectively). In different treatments, excretions of the four SAs were 35.68-86.88 %. With regard to total excretion, the order was SQ > SCP > SM1 > SDM' for all treatments. The concentration of SAs in the feed had significant effects on the amount of the four SAs excreted every day. The concentration of SAs in feces and in the urine for different treatments was 15.03-26.55 and 14.54-69.22 %, respectively. In each treatment, excretions of SCP, SDM' and SQ in feces were lower than that in urine. The four SAs remained longer in urine than in feces. Excretions in urine and feces were lower if SAs were administered orally rather than by injection.

Colorectal Cancer Risk Assessment Tool

Science.gov (United States)

... 11/12/2014 Risk Calculator About the Tool Colorectal Cancer Risk Factors Download SAS and Gauss Code Page ... Rectal Cancer: Prevention, Genetics, Causes Tests to Detect Colorectal Cancer and Polyps Cancer Risk Prediction Resources Update November ...

Standardized analyses of nuclear shipping containers

International Nuclear Information System (INIS)

Parks, C.V.; Hermann, O.W.; Petrie, L.M.; Hoffman, T.J.; Tang, J.S.; Landers, N.F.; Turner, W.D.

1983-01-01

This paper describes improved capabilities for analyses of nuclear fuel shipping containers within SCALE -- a modular code system for Standardized Computer Analyses for Licensing Evaluation. Criticality analysis improvements include the new KENO V, a code which contains an enhanced geometry package and a new control module which uses KENO V and allows a criticality search on optimum pitch (maximum k-effective) to be performed. The SAS2 sequence is a new shielding analysis module which couples fuel burnup, source term generation, and radial cask shielding. The SAS5 shielding sequence allows a multidimensional Monte Carlo analysis of a shipping cask with code generated biasing of the particle histories. The thermal analysis sequence (HTAS1) provides an easy-to-use tool for evaluating a shipping cask response to the accident capability of the SCALE system to provide the cask designer or evaluator with a computational system that provides the automated procedures and easy-to-understand input that leads to standarization

EDITORIAL Proceedings of the XIV International Conference on Small-Angle Scattering, SAS-2009

Science.gov (United States)

Ungar, Goran; Heenan, Richard

2010-10-01

particles based on the radial pair distance distribution function. The model takes account of different types of disorder, i.e. of both 1st ('thermal') and 2nd ('paracrystalline') kind, as well as finite size, stacking and orientational disorder. In paper 012014 Salvino Ciccariello works out the 3D correlation function of plane objects, specifically a triangle of a general shape. This paves the way to analysing morphologies that can be approximated by cylinders of different cross-sections. Papers 012051 (Polte et al.) and 012047 (Bras et al.) report the use of SAS in combination with X-ray spectroscopy. Ristic et al. describe a real-time study of crystal nucleation induced by ultrasound (012049), while Marianne Imperor-Clerc et al. present an investigation of lyotropic liquid crystals under shear (012052). In the Polymers section Geoff Mitchell describes modelling of SANS data on electrospun fibres (012042), while Cabral et al. describes a study of nanoparticle aggregation in bulk and thin polymer films (012046). Work on phospholipid membranes was reported by Spinozzi et al. and by Onai et al. in papers 012019 and 012018, respectively. The latter deals with the effect of osmotic pressure on model 'lipid rafts', these being considered as having an important role in the function of the mammalian cell membrane. Readers interested in biological systems will find a number of other interesting papers describing the use of either SAXS or SANS in the Biological Systems and Membranes section. A number of descriptions of recent designs of SAXS (synchrotron) and SANS beamlines, as well as detector developments can be found in the section on Beamlines and Instrumentation. Goran Ungar, Editor-in-Chief Richard Heenan, Deputy Editor-in-Chief

SASi juht : me ei ole suutäis Lufthansale / Sirje Rank

Index Scriptorium Estoniae

Rank, Sirje, 1966-

2003-01-01

SAS-i juht Jörgen Lindegaard kummutas Rootsi ajalehele Dagens Industri antud intervjuus lennufirmade France Air ja KLM ühinemisteatele järgnenud spekulatsioonid SAS-i ülevõtmisest Saksa lennukompanii Lufthansa poolt. Diagramm: lennufirmade Air France/KLM, Lufthansa, British Airways ja SAS käive 2002. aastal. Vt. samas: SAS alandab hindu

Biological Small Angle Scattering: Techniques, Strategies and Tips

Energy Technology Data Exchange (ETDEWEB)

Chaudhuri, Barnali [University at Buffalo (SUNY); Muñoz, Inés G. [Centro Nacional de Investigaciones Oncológicas Madrid, Madrid, Spain; Urban, Volker S. [ORNL; Qian, Shuo [ORNL

2017-12-01

This book provides a clear, comprehensible and up-to-date description of how Small Angle Scattering (SAS) can help structural biology researchers. SAS is an efficient technique that offers structural information on how biological macromolecules behave in solution. SAS provides distinct and complementary data for integrative structural biology approaches in combination with other widely used probes, such as X-ray crystallography, Nuclear magnetic resonance, Mass spectrometry and Cryo-electron Microscopy. The development of brilliant synchrotron small-angle X-ray scattering (SAXS) beam lines has increased the number of researchers interested in solution scattering. SAS is especially useful for studying conformational changes in proteins, highly flexible proteins, and intrinsically disordered proteins. Small-angle neutron scattering (SANS) with neutron contrast variation is ideally suited for studying multi-component assemblies as well as membrane proteins that are stabilized in surfactant micelles or vesicles. SAS is also used for studying dynamic processes of protein fibrillation in amyloid diseases, and pharmaceutical drug delivery. The combination with size-exclusion chromatography further increases the range of SAS applications.The book is written by leading experts in solution SAS methodologies. The principles and theoretical background of various SAS techniques are included, along with practical aspects that range from sample preparation to data presentation for publication. Topics covered include techniques for improving data quality and analysis, as well as different scientific applications of SAS. With abundant illustrations and practical tips, we hope the clear explanations of the principles and the reviews on the latest progresses will serve as a guide through all aspects of biological solution SAS.The scope of this book is particularly relevant for structural biology researchers who are new to SAS. Advanced users of the technique will find it helpful for

Socially Anxious Individuals Get a Second Chance After Being Disliked at First Sight: The Role of Self-Disclosure in the Development of Likeability in Sequential Social Contact.

Science.gov (United States)

Voncken, M J; Dijk, K F L

2013-02-01

Socially anxious individuals (SAs) not only fear social rejection, accumulating studies show that SAs are indeed judged as less likeable after social interaction with others. This study investigates if SAs already make a more negative impression on others in the very first seconds of contact. The study further investigates the development of likeability and the role of self-disclosure herein in two sequential social interactions: first after an unstructured waiting room situation and next after a 'getting acquainted' conversation. Results showed that high SAs (n = 24) elicited a more negative first impression than low SAs (n = 22). Also, although high SAs improved from the first to the second task, they were rated as less likeable after both interactions. The level of self-disclosure behaviour was the strongest predictor for the development of likeability during the sequential social tasks. The absence of an interaction between group and self-disclosure in predicting the development of likeability suggests that this is true for both groups. Thus, high SAs can improve their negative first impression if they are able to increase their self-disclosure behaviour. However, SAs showed a decreased level of self-disclosure behaviour during both social interactions. Targeting self-disclosure behaviour may improve the negative impression SAs elicit in others.

Reliability, validity, and responsiveness of the Persian version of Shoulder Activity Scale in a group of patients with shoulder disorders.

Science.gov (United States)

Negahban, Hossein; Mohtasebi, Elham; Goharpey, Shahin

2015-01-01

The aim of this methodological study was to cross-culturally translate the Shoulder Activity Scale (SAS) into the Persian and determine its clinimetric properties including reliability, validity, and responsiveness in patients with shoulder disorders. Persian version of the SAS was obtained after standard forward-backward translation. Three questionnaires were completed by the respondents: SAS, shoulder pain and disability index (SPADI), and Short-Form 36 Health Survey (SF-36). The patients completed the SAS, 1 week after the first visit to evaluate the test-retest reliability. Construct validity was evaluated by examining the associations between the scores on the SAS and the scores obtained from the SPADI, SF-36, and age of the patients. To assess responsiveness, data were collected in the first visit and then again after 4 weeks physiotherapy intervention. Test-retest reliability and internal consistency were assessed using Intra-class Correlation Coefficient (ICC) and Cronbach's alpha, respectively. To evaluate construct validity, Spearman's rank correlation was used. The ability of the SAS to detect changes was evaluated by the receiver-operating characteristics method. No problem or language difficulties were reported during translation process. Test-retest reliability of the SAS was excellent with an ICC of 0.98. Also, the marginal Cronbach's alpha level of 0.64 was obtained. The correlation between the SAS and the SPADI was low, proving divergent validity, whereas the correlations between the SAS and the SF-36/age were moderate proving convergent validity. A marginally acceptable responsiveness was achieved for the Persian SAS. The study provides some evidences to support the test-retest reliability, internal consistency, construct validity, and responsiveness of the Persian version of the SAS in patients with shoulder disorders. Therefore, it seems that this instrument is a useful measure of shoulder activity level in research setting and clinical practice

Development of a New Punch Head Shape to Replicate Scale-Up Issues on a Laboratory Tablet Press III: Replicating sticking phenomenon using the SAS punch and evaluation by checking the tablet surface using 3D laser scanning microscope.

Science.gov (United States)

Ito, Manabu; Aoki, Shigeru; Uchiyama, Jumpei; Yamato, Keisuke

2018-04-20

Sticking is a common observation in the scale-up stage on the punch tip using a commercial tableting machine. The difference in the total compression time between a laboratory and a commercial tableting machine is considered one of the main root causes of scale up issues in the tableting processes. The proposed Size Adjusted for Scale-up (SAS) punch can be used to adjust the consolidation and dwell times for commercial tableting machine. As a result, the sticking phenomenon is able to be replicated at the pilot scale stage. As reported in this paper, the quantification of sticking was measured using a 3D laser scanning microscope to check the tablet surface. It was shown that the sticking area decreased with the addition of magnesium stearate in the formulation, but the sticking depth was not affected by the additional amount of magnesium stearate. It is proposed that use of a 3D laser scanning microscope can be applied to evaluate sticking as a process analytical technology (PAT) tool and so sticking can be monitored continuously without stopping the machine. Copyright © 2018. Published by Elsevier Inc.

Two rare deletions upstream of the NRXN1 gene (2p16.3) affecting the non-coding mRNA AK127244 segregate with diverse psychopathological phenotypes in a family

DEFF Research Database (Denmark)

Duong, L. T. T.; Hoeffding, L. K.; Petersen, K. B.

2015-01-01

127244 in addition to the pathogenic 15q11.2 deletion in distinct family members. The two deletions upstream of the NRXN1 gene were found to segregate with psychiatric disorders in the family and further similar deletions have been observed in patients diagnosed with autism spectrum disorder. Thus, we...... susceptibility. In this study, we describe a family affected by a wide range of psychiatric disorders including early onset schizophrenia, schizophreniform disorder, and affective disorders. Microarray analysis identified two rare deletions immediately upstream of the NRXN1 gene affecting the non-coding mRNA AK...... suggest that non-coding regions upstream of the NRXN1 gene affecting AK127244 might (as NRXN1) contain susceptibility regions for a wide spectrum of neuropsychiatric disorders. (C) 2015 Elsevier Masson SAS. All rights reserved....

Death and Disability in Patients with Sleep Apnea - A Meta-analysis

Energy Technology Data Exchange (ETDEWEB)

Fonseca, Maria Inês Pires, E-mail: pinespines@gmail.com; Pereira, Telmo; Caseiro, Paulo [Instituto Politécnico de Coimbra - ESTESC - Departamento de Fisiologia Clínica, Coimbra (Portugal)

2015-01-15

Several studies have been attempting to ascertain the risks of Sleep Apnea Syndrome (SAS) and its morbidity and mortality. The main objective was to verify whether SAS increases the risk of death; the secondary objective was to evaluate its morbidity in relation to cardiovascular disease and the number of days hospitalized. A systematic review and a meta-analysis were performed of the published literature. The research focused on studies comparing the number of deaths in patients with untreated SAS and in patients with non-SAS. The meta-analysis was based on 13 articles, corresponding to a total of 13394 participants divided into two groups (non-SAS = 6631; SAS = 6763). The meta-analysis revealed a clear association of SAS with the occurrence of fatal events, where the presence of SAS corresponded to a 61% higher risk of total mortality (OR=1.61; CI: 1.43 - 1.81; p < 0.00001), while the risk of death from cardiac causes was 2.52 times higher in these patients (OR = 2.52; IC: 1.80 - 3.52; p < 0.00001). Similar results were obtained for mortality from other causes (OR = 1.68; CI: 1.08 - 2.61; p = 0.02). Resembling results were obtained in the remaining outcomes: non-fatal cardiovascular events were higher in the SAS group (OR = 2.46; IC: 1.80 - 3.36; p < 0.00001), the average number of days hospitalized was also higher in the SAS group (IV = 18.09; IC: 13.34 - 22.84; p < 0.00001). The results show that untreated SAS significantly increases the risk of death, cardiovascular events and the average number of days hospitalized.

Death and Disability in Patients with Sleep Apnea - A Meta-analysis

International Nuclear Information System (INIS)

Fonseca, Maria Inês Pires; Pereira, Telmo; Caseiro, Paulo

2015-01-01

Several studies have been attempting to ascertain the risks of Sleep Apnea Syndrome (SAS) and its morbidity and mortality. The main objective was to verify whether SAS increases the risk of death; the secondary objective was to evaluate its morbidity in relation to cardiovascular disease and the number of days hospitalized. A systematic review and a meta-analysis were performed of the published literature. The research focused on studies comparing the number of deaths in patients with untreated SAS and in patients with non-SAS. The meta-analysis was based on 13 articles, corresponding to a total of 13394 participants divided into two groups (non-SAS = 6631; SAS = 6763). The meta-analysis revealed a clear association of SAS with the occurrence of fatal events, where the presence of SAS corresponded to a 61% higher risk of total mortality (OR=1.61; CI: 1.43 - 1.81; p < 0.00001), while the risk of death from cardiac causes was 2.52 times higher in these patients (OR = 2.52; IC: 1.80 - 3.52; p < 0.00001). Similar results were obtained for mortality from other causes (OR = 1.68; CI: 1.08 - 2.61; p = 0.02). Resembling results were obtained in the remaining outcomes: non-fatal cardiovascular events were higher in the SAS group (OR = 2.46; IC: 1.80 - 3.36; p < 0.00001), the average number of days hospitalized was also higher in the SAS group (IV = 18.09; IC: 13.34 - 22.84; p < 0.00001). The results show that untreated SAS significantly increases the risk of death, cardiovascular events and the average number of days hospitalized

Stormfulde højder: En kommunikationopgave om SAS

OpenAIRE

Smedegaard, Anton; Rhein-Knudsen, Søren

2013-01-01

In this paper, we present a case study of an organization faced with identity threatening images. Building on our empirical findings, we put forward a case, in which an external negative image for government-­‐owned companies, go hand-­‐in-­‐hand with years of organizational turmoil, resulting in malfunctioning internal organizational communication. In this way, we shed light on the importance of continuously re-­‐evaluation of organizational identity, in order for management to orchestrating...

Spa Rituales Ancestrales AüA S.A.S.

OpenAIRE

Lozano Socarrás, Rosa Marina

2013-01-01

Las practicas ancestrales de las culturas precolombinas cada día son mas validas en su aplicación actual para la medicina alternativa, orientada al bienestar y la salud, es un hecho que en los últimos años se observa un gran crecimiento de endemias de estrés que se presentan bajo determinadas circunstancias propias del sistema actual de vida urbana y actividades cotidianas, ocasionando recargas de tensión como respuesta a la supervivencia en un mundo agitado. La somatizacion del estrés se tra...

Nonlinear Growth Models in M"plus" and SAS

Science.gov (United States)

Grimm, Kevin J.; Ram, Nilam

2009-01-01

Nonlinear growth curves or growth curves that follow a specified nonlinear function in time enable researchers to model complex developmental patterns with parameters that are easily interpretable. In this article we describe how a variety of sigmoid curves can be fit using the M"plus" structural modeling program and the nonlinear…

Nueva evidencia sobre la Statistical Anxiety Scale (SAS

Directory of Open Access Journals (Sweden)

Amparo Oliver

2014-01-01

Full Text Available Las asignaturas relacionadas con la estadística suelen tener problemas de rendimiento académico. La ansiedad se relaciona de forma negativa con el rendimiento y en particular, la ansiedad estadística puede ser un constructo clave en la mejora de la enseñanza de esta materia y afines. La Statistical Anxiety Scale (Vigil-Colet, Lorenzo-Seva y Condon, 2008 se creó con la pretensión de ser útil para predecir el rendimiento académico en estadística. Se fundamenta en tres dimensiones de ansiedad referidas a tres aspectos específicos: respecto al examen, cuando se pide ayuda en la comprensión de estadística y en el proceso de interpretación de resultados. Esta estructura de tres factores fue hallada en un primer momento por los autores de la escala y en una primera validación corroborada en estudiantes italianos y españoles. El presente estudio pretende añadir nueva evidencia sobre la fiabilidad y validez de la escala, empleando en el estudio de fiabilidad técnicas estadísticas robustas, y ampliando el estudio de la validez respecto a su principal criterio, el rendimiento académico, ya que no puede ser considerado sinónimo de autoeficacia.

A handbook of statistical graphics using SAS ODS

CERN Document Server

Der, Geoff

2014-01-01

An Introduction to Graphics: Good Graphics, Bad Graphics, Catastrophic Graphics and Statistical GraphicsThe Challenger DisasterGraphical DisplaysA Little History and Some Early Graphical DisplaysGraphical DeceptionAn Introduction to ODS GraphicsGenerating ODS GraphsODS DestinationsStatistical Graphics ProceduresODS Graphs from Statistical ProceduresControlling ODS GraphicsControlling Labelling in GraphsODS Graphics EditorGraphs for Displaying the Characteristics of Univariate Data: Horse Racing, Mortality Rates, Forearm Lengths, Survival Times and Geyser EruptionsIntroductionPie Chart, Bar Cha

Practice of 2D data treatment in SAS

International Nuclear Information System (INIS)

Pépy, G

2012-01-01

Many Small Angle Scattering experiments are one dimensional. Meanwhile the data of some experiments are 2 dimensional and the experimentalist may find advantages to make a full 2 dimensional data treatment or cannot avoid it. 2 dimensional data treatments present specific difficulties. The first one is an appropriate display of the whole data and of the most important part of them, in a way significant for the scientist. The second difficulty comes from the bad statistics of data which cannot be grouped together. In the following paper we describe various solutions to these problems, developed through a very long practice in LLB (Saclay, France) and SzFKI (Budapest, Hungary).

A Qualitative Exploration of Former College Student-Athletes’ Wellness

Directory of Open Access Journals (Sweden)

Warehime Shane

2017-10-01

Full Text Available College student-athletes (SAs may experience difficulties while transitioning from college, which could reduce their overall wellness. However, it is essential to understand positive transition experiences and outcomes, as this can guide future research and intervention efforts. The purpose of this study was to explore the factors that led to higher levels of wellness in former SAs. Semi-structured interviews guided by the Indivisible Self Model were completed with former SAs (n = 12. Overall, participants displayed high levels of wellness - most prominently in terms of work and exercise. Many SAs perceived their current wellness was equal, if not better compared to when they were SAs. These results illustrate examples of successful transitions of former SAs, which can guide future research and interventions.

Space sickness on earth

Science.gov (United States)

Nooij, S. A. E.; Bos, J. E.; Groen, E. L.; Bles, W.; Ockels, W. J.

2007-09-01

During the first days in space, i.e., after a transition from 1G to 0G, more than 50% of the astro- (and cosmonauts) suffer from the Space Adaptation Syndrome (SAS).The symptoms of SAS, like nausea and dizziness, are especially provoked by head movements. Astronauts have mentioned close similarities between the symptoms of SAS and the symptoms they experienced after a 1 hour centrifuge run on Earth, i.e., after a transition from 3G to 1G (denoted by Sickness Induced by Centrifugation, SIC). During several space missions, we related susceptibility to SAS and to SIC in 11 astronauts and found 4 of them being susceptible to both SIC and SAS, and 7 being not susceptible to SIC nor to SAS. This correspondence in susceptibility suggests that SIC and SAS share the same underlying mechanism. To further study this mechanism, several vestibular parameters have been investigated (e.g. postural stability, vestibularly driven eye movements, subjective vertical). We found some striking changes in individual cases that are possibly due to the centrifuge run. However, the variability between subjects generally is very large, making physiological links to SIC and SAS still hard to find.

Comparative analysis of unprotected loss-of-flow accidents for the 1.0 m EFR-LVC core using different computer codes

International Nuclear Information System (INIS)

Royl, P.; Frizonnet, J.M.; Moran, J.

1993-02-01

A comparative analysis of the unprotected loss of flow (ULOF) accident has been performed for the LVC core (Lower Void Core) of the European Fast Reactor EFR with the FRAX5B and FRAX5C codes from the AEA-T, the PHYSURAC code from CEA and the SAS4A REF92 code system developed jointly between KfK, CEA and PNC. The accident is triggered by the run down of the coolant pumps with failure to trip the reactor by the primary and/or secondary shutdown system. Only a limited amount of mitigating reactivity from the third shutdown line was considered so that the accident can progress into boiling and core disruption. This code outlines the important modelling differences and compares the different simulations. The discussion of the rather wide spectrum of calculated accident progressions identifies the generic differences, relates them to the applied models, and summarizes the key points that are responsible for the different progressions. A comparison of the consequence spectrum from all simulations indicates zero work energies for the majority of the calculations. All simulations show up the need for a continued accident analysis into the early and late transition phase

Genetic evidence of subaortic stenosis in the Newfoundland dog.

Science.gov (United States)

Reist-Marti, S B; Dolf, G; Leeb, T; Kottmann, S; Kietzmann, S; Butenhoff, K; Rieder, S

2012-06-09

Subaortic stenosis (SAS) is a cardiac disorder with a narrowing of the descending aorta below the left ventricular outflow tract of the heart. It occurs in several species and breeds. The Newfoundland is one of the dog breeds where it is more common and usually leads to death at early adulthood. It is still discussed to which extent SAS has a genetic background and what its mode of inheritance could be. Extensive pedigree data comprising more than 230,000 Newfoundland dogs from the European and North American population reaching back to the 19th century including 6023 dogs with a SAS diagnosis were analysed for genetic factors influencing SAS affection. The incidence and prevalence of SAS in the analysed Newfoundland population sample were much higher than those reported in previous studies on smaller population samples. Assuming that some SAS-affected dogs remained undiscovered or were not reported, these figures may even be underestimated. SAS-affected Newfoundland dogs were more often inbred and closer related to each other than unaffected dogs, which is an indicator for a genetic background of SAS. The sex had no significant impact on SAS affectedness, pointing at an autosomal inheritance. The only simple mode of inheritance that fitted the data well was autosomal codominant with lethal homozygosity and a penetrance of 1/3 in the heterozygotes.

Severity of angular leaf spot and rust diseases on common beans in ...

African Journals Online (AJOL)

ACSS

5.3, respectively. Key words: Common beans, disease management, Phaseolus vulgaris, Pseudocercospora griseola, .... Pearson product- moment ..... SAS Institute. 1989. SAS/STAT User's. Guide (version 6, vol. 1, 4th ed.), Cary: SAS Institute ...

Association between aortoseptal angle in Golden Retriever puppies and subaortic stenosis in adulthood.

Science.gov (United States)

Belanger, M C; Côté, E; Beauchamp, G

2014-01-01

Predicting subaortic stenosis (SAS) in adult Golden Retriever dogs (GRs) by evaluating them as puppies is hampered by the progressive expression of the SAS phenotype in youth. In some children who develop SAS as adults, an abnormal aortoseptal angle (AoSA) precedes development of stenosis. To determine the normal AoSA in young adult GRs using echocardiography; to assess the value of AoSA in GR puppies for predicting development of the SAS phenotype. Forty-eight 2- to 6-month-old GR puppies. Prospective study. Puppies were recruited from clients and breeders. Puppies were evaluated with a physical examination and an echocardiogram, and this evaluation was repeated when they were 12-18-month-old adults. Puppies were classified as unaffected (WNL) or affected (SAS) retroactively, based on their results as adults. In WNL young adult GRs, mean ± SD AoSA was 152.3 ± 6.5°. Mean ± SD AoSA in SAS puppies (144.9 ± 8.6°) was significantly different from mean AoSA in WNL puppies (155.7 ± 8.8°, P 160° had the SAS phenotype as a young adult; 93% (75.7-99.1%) of puppies with AoSA <145° had the SAS phenotype as young adults. Peak LVOT velocity increased significantly between evaluations (P < .0001) whereas AoSA did not (P = .45). A steep AoSA in GR puppies is associated with the SAS phenotype in young adulthood. Some GR puppies have an abnormal AoSA that persists in young adulthood and is detectable before peak LVOT velocity reaches levels consistent with SAS. Copyright © 2014 by the American College of Veterinary Internal Medicine.

Evaluation of two formulations of adjuvanted RTS, S malaria vaccine in children aged 3 to 5 years living in a malaria-endemic region of Mozambique: a Phase I/IIb randomized double-blind bridging trial

Directory of Open Access Journals (Sweden)

Mandomando Inacio

2007-03-01

Full Text Available Abstract Background Previous trials of the RTS, S malaria candidate vaccine have shown that this vaccine is safe, tolerated and immunogenic. The development plan for this vaccine aims at administering it in the first year of life through the Expanded Program on Immunization (EPI. The objective was to evaluate the safety and reactogenicity of RTS, S/AS02D (0.5 ml dose, a pediatric formulation of GlaxoSmithKline Biologicals' current malaria candidate vaccine RTS, S/AS02A (0.25 ml dose. A 0.5 ml dose of AS02D is composed of the same active ingredients in the same quantities as in a 0.25 ml dose of AS02A and has been developed to be easily introduced into routine EPI practices. Methods We performed a phase I/IIb randomized double-blind bridging study in a malaria-endemic region of Mozambique, to compare the safety and immunogenicity of both candidate vaccines with the aim of replacing RTS, S/AS02A with RTS, S/AS02D as the candidate pediatric vaccine. 200 Mozambican children aged 3 to 5 years were randomized 1:1 to receive one of the 2 vaccines according to a 0, 1, 2 month schedule. Results Both vaccines were safe and had similar reactogenicity profiles. All subjects with paired pre and post-vaccination samples showed a vaccine response with respect to anti-circumsporozoite (CS antibodies irrespective of initial anti-CS serostatus. Geometric mean titers (GMTs were 191 EU/ml (95% CI 150–242 in recipients of RTS, S/AS02D compared to 180 EU/ml (95% CI 146–221 in recipients of RTS, S/AS02A. For the anti-hepatitis B surface antigen (HBsAg, all subjects were seroprotected at day 90, and the GMTs were 23978 mIU/ml (95% CI 17896–32127 in RTS, S/AS02D recipients and 17410 mIU/ml (95% CI 13322–22752 in RTS, S/AS02A recipients. There was a decrease in anti-CS GMTs between months 3 and 14 in both groups (191 vs 22 EU/mL in RTS, S/AS02D group and 180 vs 29 EU/mL in RTS, S/AS02A group. Conclusion Our data show that the RTS, S/AS02D is safe, well tolerated

Simultaneous micronization and purification of bioactive fraction by supercritical antisolvent technology

Directory of Open Access Journals (Sweden)

Stevanus Hiendrawan

2017-01-01

Full Text Available Simultaneous micronization and purification of DLBS3233 bioactive fraction, a combination of two Indonesian herbals Lagerstroemia speciosa and Cinnamomum burmannii has been successfully performed via supercritical anti-solvent (SAS technology. The objective of the present study was to investigate the effectiveness of SAS technology to micronize and reduce coumarin content of DLBS3233. The effects of four SAS process parameters, i.e. pressure, temperature, concentration and solution flow rate on particle formation were investigated. In SAS process, DLBS3233 was dissolved in dimethylformamide (DMF as the liquid solvent. The solution was then pumped through a nozzle into a chamber simultaneously with supercritical carbon dioxide (SC-CO2 which acts as the anti-solvent, resulting in DLBS3233 precipitation. Physicochemical properties of unprocessed DLBS3233 and SAS-processed DLBS3233 particles were analyzed using scanning electron microscopy (SEM and high pressure liquid chromatography (HPLC. Total polyphenol content (TPC was also analyzed.Particles with mean particle size ranging from 0.107±0.028 μm to 0.298±0.138 μm were obtained by varying the process parameters. SAS-processed DLBS3233 particles showed no coumarin content in all experiments studied in this work. Results of TPC analysis revealed no significant change in SAS-processed DLBS3233 particles compared to unprocessed DLBS3233. Nano-sized DLBS3233 particles with no coumarin content have been successfully produced using SAS process. This study demonstrates the ability of SAS for processing herbal medicine in single step process.

The StartReact Effect on Self-Initiated Movements

Directory of Open Access Journals (Sweden)

J. M. Castellote

2013-01-01

Full Text Available Preparation of the motor system for movement execution involves an increase in excitability of motor pathways. In a reaction time task paradigm, a startling auditory stimulus (SAS delivered together with the imperative signal (IS shortens reaction time significantly. In self-generated tasks we considered that an appropriately timed SAS would have similar effects. Eight subjects performed a ballistic wrist extension in two blocks: reaction, in which they responded to a visual IS, and action, in which they moved when they wished within a predetermined time window. In 20–25% of the trials, a SAS was applied. We recorded electromyographic activity of wrist extension and wrist movement kinematic variables. No effects of SAS were observed in action trials when movement was performed before or long after SAS application. However, a cluster of action trials was observed within 200 ms after SAS. These trials showed larger EMG bursts, shorter movement time, shorter time to peak velocity, and higher peak velocity than other action trials (P<0.001 for all, with no difference from Reaction trials containing SAS. The results show that SAS influences the execution of self-generated human actions as it does with preprogrammed reaction time tasks during the assumed building up of preparatory activity before execution of the willed motor action.

Reliability of the Arabic Smartphone Addiction Scale and Smartphone Addiction Scale-Short Version in Two Different Moroccan Samples.

Science.gov (United States)

Sfendla, Anis; Laita, Meriame; Nejjar, Basma; Souirti, Zouhayr; Touhami, Ahami Ahmed Omar; Senhaji, Meftaha

2018-05-01

The extensive accessibility to smartphones in the last decade raises the concerns of addictive behavior patterns toward these technologies worldwide and in developing countries, and Arabic ones in particular. In an area of stigmatized behavior such as Internet and smartphone addiction, the hypothesis extends to whether there is a reliable instrument that can assess smartphone addiction. To our knowledge, no scale in Arabic language is available to assess maladaptive behavior associated with smartphone use. This study aims to assess the factorial validity and internal reliability of the Arabic Smartphone Addiction Scale (SAS) and Smartphone Addiction Scale-Short Version (SAS-SV) in a Moroccan surveyed population. Participants (N = 440 and N = 310) completed an online survey, including SAS, SAS-SV, and questions about sociodemographic status. Factor analysis results showed six factors with factor loading ranging from 0.25 to 0.99 for SAS. Reliability, based on Cronbach's alpha, was excellent (α = 0.94) for this instrument. The SAS-SV showed one factor (unidimensional construct), and internal reliability was in the good range with an alpha coefficient of (α = 0.87). The prevalence of excessive users was 55.8 percent with highest symptom prevalence reported for tolerance and preoccupation. This study proved factor validity of the Arabic SAS and SAS-SV instruments and confirmed their internal reliability.

Small angle slot divertor concept for long pulse advanced tokamaks

Science.gov (United States)

Guo, H. Y.; Sang, C. F.; Stangeby, P. C.; Lao, L. L.; Taylor, T. S.; Thomas, D. M.

2017-04-01

SOLPS-EIRENE edge code analysis shows that a gas-tight slot divertor geometry with a small-angle (glancing-incidence) target, named the small angle slot (SAS) divertor, can achieve cold, dissipative/detached divertor conditions at relatively low values of plasma density at the outside midplane separatrix. SAS exhibits the following key features: (1) strong enhancement of the buildup of neutral density in a localized region near the plasma strike point on the divertor target; (2) spreading of the cooling front across the divertor target with the slot gradually flaring out from the strike point, thus effectively reducing both heat flux and erosion on the entire divertor target surface. Such a divertor may potentially provide a power and particle handling solution for long pulse advanced tokamaks.

Some recriticality studies with SIMMER-II

International Nuclear Information System (INIS)

Bohl, W.R.

1979-01-01

The SIMMER-II code was applied to the problem of evaluating the potential for recriticality in an LMFBR HCDA. The phenomenology examined was based on the post SAS3D behavior in a CRBR LOF accident. The SIMMER-II results were found to be sensitive to the development of fuel blockages. If blockages were formed close to the core, the core-disruption phase of the behavior resulted from the significant energy required following SAS3D termination to raise the average steel temperature to saturation conditions; also material deposition near heat sinks eliminated condensation surfaces and induced core pressurization and fuel collapse. Excessive ramp rates (greater than $100/s) were judged to be unlikely, but improved knowledge and calculational treatments of the applicable phenomenology would be desirable

Socially anxious individuals get a second chance after being disliked at first sight: The role of self-disclosure in the development of likeability in sequential social contact

NARCIS (Netherlands)

Voncken, M.J.; Dijk, K.F.L.

2013-01-01

Socially anxious individuals (SAs) not only fear social rejection, accumulating studies show that SAs are indeed judged as less likeable after social interaction with others. This study investigates if SAs already make a more negative impression on others in the very first seconds of contact. The

Sonar path correction in synthetic aperture processing

NARCIS (Netherlands)

Groen, J.; Hansen, R.E.; Sabel, J.C.

2003-01-01

In the next generation of mine hunting sonars, in particular on Autonomous Underwater Vehicles (AUVs), Synthetic Aperture Sonar (SAS) will play an important role. The benefit of SAS is to increase resolution and signal-tonoise ratio by coherent processing of successive pings. A challenge in SAS is

Estonian Airi ümber käib lehmakauplemine / Tõnu Lilleorg

Index Scriptorium Estoniae

Lilleorg, Tõnu

2008-01-01

Skandinaavia lennukompanii SAS saatis Eesti valitsusele kirja, milles teatab, et on nõus raskustes Estonian Airile lisainvesteeringuid tegema vaid siis, kui riik müüb SAS-ile oma osaluse, 34%. Vt. samas: SAS ei taha lennufirma eest maksta üle 150 miljoni. Diagramm: Majandusnäitajad, omanikud

The toxicological mode of action and the safety of synthetic amorphous silica—A nanostructured material

International Nuclear Information System (INIS)

Fruijtier-Pölloth, Claudia

2012-01-01

Synthetic amorphous silica (SAS), in the form of pyrogenic (fumed), precipitated, gel or colloidal SAS, has been used in a wide variety of industrial and consumer applications including food, cosmetics and pharmaceutical products for many decades. Based on extensive physico-chemical, ecotoxicology, toxicology, safety and epidemiology data, no environmental or health risks have been associated with these materials if produced and used under current hygiene standards and use recommendations. With internal structures in the nanoscale size range, pyrogenic, precipitated and gel SAS are typical examples of nanostructured materials as recently defined by the International Organisation for Standardisation (ISO). The manufacturing process of these SAS materials leads to aggregates of strongly (covalently) bonded or fused primary particles. Weak interaction forces (van der Waals interactions, hydrogen bonding, physical adhesion) between aggregates lead to the formation of micrometre (μm)-sized agglomerates. Typically, isolated nanoparticles do not occur. In contrast, colloidal SAS dispersions may contain isolated primary particles in the nano-size range which can be considered nano-objects. The size of the primary particle resulted in the materials often being considered as “nanosilica” and in the inclusion of SAS in research programmes on nanomaterials. The biological activity of SAS can be related to the particle shape and surface characteristics interfacing with the biological milieu rather than to particle size. SAS adsorbs to cellular surfaces and can affect membrane structures and integrity. Toxicity is linked to mechanisms of interactions with outer and inner cell membranes, signalling responses, and vesicle trafficking pathways. Interaction with membranes may induce the release of endosomal substances, reactive oxygen species, cytokines and chemokines and thus induce inflammatory responses. None of the SAS forms, including colloidal nano-sized particles, were

The toxicological mode of action and the safety of synthetic amorphous silica-a nanostructured material.

Science.gov (United States)

Fruijtier-Pölloth, Claudia

2012-04-11

Synthetic amorphous silica (SAS), in the form of pyrogenic (fumed), precipitated, gel or colloidal SAS, has been used in a wide variety of industrial and consumer applications including food, cosmetics and pharmaceutical products for many decades. Based on extensive physico-chemical, ecotoxicology, toxicology, safety and epidemiology data, no environmental or health risks have been associated with these materials if produced and used under current hygiene standards and use recommendations. With internal structures in the nanoscale size range, pyrogenic, precipitated and gel SAS are typical examples of nanostructured materials as recently defined by the International Organisation for Standardisation (ISO). The manufacturing process of these SAS materials leads to aggregates of strongly (covalently) bonded or fused primary particles. Weak interaction forces (van der Waals interactions, hydrogen bonding, physical adhesion) between aggregates lead to the formation of micrometre (μm)-sized agglomerates. Typically, isolated nanoparticles do not occur. In contrast, colloidal SAS dispersions may contain isolated primary particles in the nano-size range which can be considered nano-objects. The size of the primary particle resulted in the materials often being considered as "nanosilica" and in the inclusion of SAS in research programmes on nanomaterials. The biological activity of SAS can be related to the particle shape and surface characteristics interfacing with the biological milieu rather than to particle size. SAS adsorbs to cellular surfaces and can affect membrane structures and integrity. Toxicity is linked to mechanisms of interactions with outer and inner cell membranes, signalling responses, and vesicle trafficking pathways. Interaction with membranes may induce the release of endosomal substances, reactive oxygen species, cytokines and chemokines and thus induce inflammatory responses. None of the SAS forms, including colloidal nano-sized particles, were shown

Validation of a Malay Version of the Smartphone Addiction Scale among Medical Students in Malaysia.

Directory of Open Access Journals (Sweden)

Siew Mooi Ching

Full Text Available This study was initiated to determine the psychometric properties of the Smart Phone Addiction Scale (SAS by translating and validating this scale into the Malay language (SAS-M, which is the main language spoken in Malaysia. This study can distinguish smart phone and internet addiction among multi-ethnic Malaysian medical students. In addition, the reliability and validity of the SAS was also demonstrated.A total of 228 participants were selected between August 2014 and September 2014 to complete a set of questionnaires, including the SAS and the modified Kimberly Young Internet addiction test (IAT in the Malay language.There were 99 males and 129 females with ages ranging from 19 to 22 years old (21.7±1.1 included in this study. Descriptive and factor analyses, intra-class coefficients, t-tests and correlation analyses were conducted to verify the reliability and validity of the SAS. Bartlett's test of sphericity was significant (p <0.01, and the Kaiser-Mayer-Olkin measure of sampling adequacy for the SAS-M was 0.92, indicating meritoriously that the factor analysis was appropriate. The internal consistency and concurrent validity of the SAS-M were verified (Cronbach's alpha = 0.94. All of the subscales of the SAS-M, except for positive anticipation, were significantly related to the Malay version of the IAT.This study developed the first smart phone addiction scale among medical students. This scale was shown to be reliable and valid in the Malay language.

Progress of studies on preparation of TiO2 photocatalysts with sol-gel auto igniting synthesis

Science.gov (United States)

Wu, Di; Shi, Zaifeng; Zhang, Xiaopeng; Xinghui, Wu

2017-11-01

In this article, influencing factors on the kinetics of the process of Sol-gel Auto igniting Synthesis (SAS) which is an advanced technology for preparing nanometer particles of inorganic materials were reviewed. The studies on preparing of nanometer TiO2 photocatalysts with SAS were focused. It was concluded that SAS will play an important role in practical preparing of high-pure nanometer TiO2 powder, and as a technical support, preparation of titania TiO2 from titanic iron ore with SAS is feasible and practicable.

Inhaled hyaluronic acid microparticles extended pulmonary retention and suppressed systemic exposure of a short-acting bronchodilator

DEFF Research Database (Denmark)

Li, Ying; Han, Meihua; Liu, Tingting

2017-01-01

The aim of this study was to investigate the feasibility of using hyaluronic acid (HA), a biomucoadhesive carbohydrate polymer to prolong the pulmonary retention and reduce the systemic exposure of inhaled medicine. Salbutamol sulphate (SAS), a model bronchodilator, was co-spray dried with HA...... to spray-dried plain SAS powders, the SAS-loaded HA microparticles possessed enhanced biomucoadhesive property in vitro and had much longer pulmonary retention and reduced systemic exposure in vivo. By incorporation, the pulmonary retention time of SAS was prolonged from 2h to 8h while the maximum...

The significance of morphological changes in the brain-tumor interface for the pathogenesis of brain edema in meningioma: Magnetic resonance tomography and intraoperative findings

International Nuclear Information System (INIS)

Bitzer, M.; Klose, U.; Naegele, T.; Mundinger, P.; Voigt, K.; Freudenstein, D.; Heiss, E.

1999-01-01

Purpose: The aim of the study was to verify a possible correlation between macroscopic changes of the brain-tumor interface (BTI) and the development of a peritumoral brain edema in meningiomas. Methods: 27 meningiomas were investigated in this prospective study using an optimized inversion-recovery (IR) sequence. After i.v. administration of 0.2 mmol Gd-DTPA/kg axial and coronary images were acquired (slice thickness=2 mm). The distances of signal altered cortex and obliterations of the subarachnoid space (SAS) were measured at the BTI and related to the pial tumor circumference (cortical-index and SAS-index). Intraoperatively the BTI was divided into the following categories: 0: SAS not obliterated, 1: SAS partially obliterated, 2: Direct contact between tumor and white matter, 3: Tumor infiltration into brain. Results: Edema-associated meningiomas showed a significantly (p=0.0001) increased SAS-index (0.47 vs. 0.07) and cortical index (0.45 vs. 0.0) compared to cases without edema. Intraoperatively 95% of meningiomas with brain edema showed SAS-obliterations, compared to 50% of cases without an edema. Conclusions: Arachnoid adhesions at the BTI with obliteration of the SAS seem to play an essential role in the induction of brain edema in meningiomas. (orig.) [de

Development of the ANL plant dynamics code and control strategies for the supercritical carbon dioxide Brayton cycle and code validation with data from the Sandia small-scale supercritical carbon dioxide Brayton cycle test loop.

Energy Technology Data Exchange (ETDEWEB)

Moisseytsev, A.; Sienicki, J. J. (Nuclear Engineering Division)

2011-11-07

Significant progress has been made in the ongoing development of the Argonne National Laboratory (ANL) Plant Dynamics Code (PDC), the ongoing investigation and development of control strategies, and the analysis of system transient behavior for supercritical carbon dioxide (S-CO{sub 2}) Brayton cycles. Several code modifications have been introduced during FY2011 to extend the range of applicability of the PDC and to improve its calculational stability and speed. A new and innovative approach was developed to couple the Plant Dynamics Code for S-CO{sub 2} cycle calculations with SAS4A/SASSYS-1 Liquid Metal Reactor Code System calculations for the transient system level behavior on the reactor side of a Sodium-Cooled Fast Reactor (SFR) or Lead-Cooled Fast Reactor (LFR). The new code system allows use of the full capabilities of both codes such that whole-plant transients can now be simulated without additional user interaction. Several other code modifications, including the introduction of compressor surge control, a new approach for determining the solution time step for efficient computational speed, an updated treatment of S-CO{sub 2} cycle flow mergers and splits, a modified enthalpy equation to improve the treatment of negative flow, and a revised solution of the reactor heat exchanger (RHX) equations coupling the S-CO{sub 2} cycle to the reactor, were introduced to the PDC in FY2011. All of these modifications have improved the code computational stability and computational speed, while not significantly affecting the results of transient calculations. The improved PDC was used to continue the investigation of S-CO{sub 2} cycle control and transient behavior. The coupled PDC-SAS4A/SASSYS-1 code capability was used to study the dynamic characteristics of a S-CO{sub 2} cycle coupled to a SFR plant. Cycle control was investigated in terms of the ability of the cycle to respond to a linear reduction in the electrical grid demand from 100% to 0% at a rate of 5

Topographic characteristics after Descemet's membrane endothelial keratoplasty and Descemet's stripping automated endothelial keratoplasty.

Directory of Open Access Journals (Sweden)

Takahiko Hayashi

Full Text Available To investigate the topographic characteristics of the posterior corneal surface after Descemet's endothelial membrane keratoplasty (DMEK and Descemet's stripping automated endothelial keratoplasty (DSAEK and their effects on postoperative visual acuity.Nineteen eyes of 19 patients after DMEK, 23 eyes of 23 patients after DSAEK, and 18 eyes of 18 control subjects were retrospectively analyzed. Best spectacle-corrected visual acuity (BSCVA, aberration factors (higher-order aberrations [HOAs], spherical aberrations [SAs], and coma aberrations [Comas] at 6.0 mm were evaluated preoperatively and at 1, 3, and 6 months postoperatively. The posterior refractive pattern of the topography map was classified into 5 grades (0-5 (posterior color grade using anterior segment optical coherence tomography. Correlations between BSCVA and some factors (abbreviation factors, posterior color grade were analyzed.BSCVA was significantly better after DMEK than after DSAEK (P < 0.001. Posterior HOAs, SAs, and Comas after each type of endothelial keratoplasty were significantly greater compared to control (P < 0.01. Posterior HOAs, total/anterior/posterior SAs, and posterior color grade were significantly lower in the DMEK group than in the DSAEK group at 3 months (P < 0.024 [posterior HOAs], P = 0.047 [total SA], P < 0.001 [anterior SAs], P = 0.021 [posterior SAs], and P < 0.001 [posterior color grade] and 6 months postoperatively (P = 0.034 [posterior HOAs], P < 0.001 [total SAs], P < 0.001 [anterior SAs], P = 0.013 [posterior SAs], and P = 0.004 [posterior color grade]. BSCVA was significantly correlated with HOAs, SAs, and posterior color grade (P < 0.001 for all except anterior HOAs [P = 0.004].High posterior color grades were associated with larger aberration factors and had a negative effect on visual function after endothelial keratoplasty. Rapid improvement of visual function after DMEK may be attributed to less change at the posterior surface.

Provider Specific Data for Public Use in SAS Format

Data.gov (United States)

U.S. Department of Health & Human Services — The Fiscal Intermediary maintains the Provider Specific File (PSF). The file contains information about the facts specific to the provider that affects computations...

Centriolar CPAP/SAS-4 Imparts Slow Processive Microtubule Growth

NARCIS (Netherlands)

Sharma, Ashwani; Aher, Amol; Dynes, Nicola J; Frey, Daniel; Katrukha, Eugene A; Jaussi, Rolf; Grigoriev, Ilya; Croisier, Marie; Kammerer, Richard A; Akhmanova, Anna; Gönczy, Pierre; Steinmetz, Michel O

2016-01-01

Centrioles are fundamental and evolutionarily conserved microtubule-based organelles whose assembly is characterized by microtubule growth rates that are orders of magnitude slower than those of cytoplasmic microtubules. Several centriolar proteins can interact with tubulin or microtubules, but how

Symposium on atomic spectroscopy (SAS-83): abstracts and program

International Nuclear Information System (INIS)

1983-09-01

Abstracts of papers given at the symposium are presented. Session topics include: Rydbergs, optical radiators, and planetary atoms; highly ionized atoms; ultraviolet radiation; theory, ion traps, and laser cooling; beam foil; and astronomy

Effect of the p53 gene status on the sensitivity of oral squamous cell carcinoma cells to boron neutron capture therapy

International Nuclear Information System (INIS)

Fujita, Y.; Kamida, A.; Kato, I.; Yura, Y.; Ono, K.; Suzuki, M.; Sakurai, Y.; Ohnishi, T.; Ohnishi, K.

2006-01-01

The role of the p53 gene in the sensitivity of oral squamous cell carcinoma (SCC) to boron neutron capture therapy (BNCT) had not been studied. We examined the effect of boronophenylalanine (BPA)-mediated BNCT on oral SCC cells showing either wild-type p53 (SAS/neo) or mutated-type p53 (SAS/mp53). Survival ratio of cells was determined by colony formation. Cell viability was measured by MTT assay. Apoptotic cells were evaluated by flow cytometric analysis and nuclear DNA staining. When SAS/neo and SAS/mp53 cells were subjected to BNCT, more suppressive effects on colony formation and cell viability were observed in SAS/neo cells as compared with SAS/mp53. The proportion of apoptotic cells with DNA fragmentation was also increased in the cells with functional p53. These results suggest that oral SCC cells with mutated p53 cells are more resistant to BNCT than those with wild-type p53. BNCT must inhibit oral SCC cells in p53-dependent and p53-independent mechanisms. (author)

Antibrowning and antimicrobial properties of sodium acid sulfate in apple slices.

Science.gov (United States)

Fan, Xuetong; Sokorai, Kimberly J B; Liao, Ching-Hsing; Cooke, Peter; Zhang, Howard Q

2009-01-01

There are few available compounds that can both control browning and enhance microbial safety of fresh-cut fruits. In the present study, the antibrowning ability of sodium acid sulfate (SAS) on "Granny Smith" apple slices was first investigated in terms of optimum concentration and treatment time. In a separate experiment, the apple slices were treated with water or 3% of SAS, calcium ascorbate, citric acid, or acidified calcium sulfate for 5 min. Total plate count, color, firmness, and tissue damage were assessed during a 21-d storage at 4 degrees C. Results showed that the efficacy of SAS in inhibiting browning of apple slices increased with increasing concentration. A minimum 3% of SAS was needed to achieve 14 d of shelf life. Firmness was not significantly affected by SAS at 3% or lower concentrations. Antibrowning potential of SAS was similar for all treatment times ranging from 2 to 10 min. However, SAS caused some skin discoloration of apple slices. When cut surface of apple slices were stained with a fluorescein diacetate solution, tissue damage could be observed under a microscope even though visual damage was not evident. Among the antibrowning agents tested, SAS was the most effective in inhibiting browning and microbial growth for the first 14 d. Total plate count of samples treated with 3% SAS was significantly lower than those treated with calcium ascorbate, a commonly used antibrowning agent. Our results suggested that it is possible to use SAS to control browning while inhibiting the growth of microorganisms on the apple slices if the skin damage can be minimized. Practical Application: Fresh-cut apples have emerged as one of the popular products in restaurants, schools, and food service establishments as more consumers demand fresh, convenient, and nutritious foods. Processing of fresh-cut apples induces mechanical damage to the fruit and exposes apple tissue to air, resulting in the development of undesirable tissue browning. The fresh

76 FR 59483 - Additional Designations, Foreign Narcotics Kingpin Designation Act

Science.gov (United States)

2011-09-26

... AMAZONICOS S.A.S., Bogota, Colombia; c/o PARQUES TEMATICOS S.A.S., Medellin, Colombia; c/o PROMO RAIZ S.A.S..., Distrito Federal, Mexico; c/o PARQUES TEMATICOS S.A., Medellin, Colombia; c/o PROMO RAIZ S.A., Medellin... 16 Sur No. 46A-49 Piso 6, Medellin, Colombia; NIT 800220730-4 (Colombia) [SDNTK] 7. PARQUES TEMATICOS...

Personality disorders and suicide attempts in unipolar and bipolar mood disorders.

Science.gov (United States)

Jylhä, Pekka; Rosenström, Tom; Mantere, Outi; Suominen, Kirsi; Melartin, Tarja; Vuorilehto, Maria; Holma, Mikael; Riihimäki, Kirsi; Oquendo, Maria A; Keltikangas-Järvinen, Liisa; Isometsä, Erkki T

2016-01-15

Comorbid personality disorders may predispose patients with mood disorders to suicide attempts (SAs), but factors mediating this effect are not well known. Altogether 597 patients from three prospective cohort studies (Vantaa Depression Study, Jorvi Bipolar Study, and Vantaa Primary Care Depression Study) were interviewed at baseline, at 18 months, and in VDS and PC-VDS at 5 years. Personality disorders (PDs) at baseline, number of previous SAs, life-charted time spent in major depressive episodes (MDEs), and precise timing of SAs during follow-up were determined and investigated. Overall, 219 (36.7%) patients had a total of 718 lifetime SAs; 88 (14.7%) patients had 242 SAs during the prospective follow-up. Having any PD diagnosis increased the SA rate, both lifetime and prospectively evaluated, by 90% and 102%, respectively. All PD clusters increased the rate of new SAs, although cluster C PDs more than the others. After adjusting for time spent in MDEs, only cluster C further increased the SA rate (by 52%). Mediation analyses of PD effects on prospectively ascertained SAs indicated significant mediated effects through time at risk in MDEs, but also some direct effects. Findings generalizable only to patients with mood disorders. Among mood disorder patients, comorbid PDs increase the risk of SAs to approximately two-fold. The excess risk is mostly due to patients with comorbid PDs spending more time in depressive episodes than those without. Consequently, risk appears highest for PDs that most predispose to chronicity and recurrences. However, also direct risk-modifying effects of PDs exist. Copyright © 2015 Elsevier B.V. All rights reserved.

A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs.

Science.gov (United States)

Stern, Joshua A; White, Stephen N; Lehmkuhl, Linda B; Reina-Doreste, Yamir; Ferguson, Jordan L; Nascone-Yoder, Nanette M; Meurs, Kathryn M

2014-09-01

Familial subvalvular aortic stenosis (SAS) is one of the most common congenital heart defects in dogs and is an inherited defect of Newfoundlands, golden retrievers and human children. Although SAS is known to be inherited, specific genes involved in Newfoundlands with SAS have not been defined. We hypothesized that SAS in Newfoundlands is inherited in an autosomal dominant pattern and caused by a single genetic variant. We studied 93 prospectively recruited Newfoundland dogs, and 180 control dogs of 30 breeds. By providing cardiac screening evaluations for Newfoundlands we conducted a pedigree evaluation, genome-wide association study and RNA sequence analysis to identify a proposed pattern of inheritance and genetic loci associated with the development of SAS. We identified a three-nucleotide exonic insertion in phosphatidylinositol-binding clathrin assembly protein (PICALM) that is associated with the development of SAS in Newfoundlands. Pedigree evaluation best supported an autosomal dominant pattern of inheritance and provided evidence that equivocally affected individuals may pass on SAS in their progeny. Immunohistochemistry demonstrated the presence of PICALM in the canine myocardium and area of the subvalvular ridge. Additionally, small molecule inhibition of clathrin-mediated endocytosis resulted in developmental abnormalities within the outflow tract (OFT) of Xenopus laevis embryos. The ability to test for presence of this PICALM insertion may impact dog-breeding decisions and facilitate reduction of SAS disease prevalence in Newfoundland dogs. Understanding the role of PICALM in OFT development may aid in future molecular and genetic investigations into other congenital heart defects of various species.

Experimental-laboratory studies of a composition based on TS-10 resin designed for insulation operations

Energy Technology Data Exchange (ETDEWEB)

Vyazel' shchikov, V M; Glukhov, A M

1979-01-01

Results are presented from studying the technological parameters of a strengthened argillaceous solution (SAS) conducted using the method of planning partial experiments. Particular empirical relationships are found which provide a concept about the degree of influence of each of the SAS components (TS-10 resins of paraform, water, clay) on the rate of structure-formation and mechanical strength. Summary relationships are obtained: the time for viscosity to reach 500% cP-SAS composition and ultimate compression strength SAS composition which can be used in selecting the formula for the mixture for the insulation operations in an ''cold'' well.

Using SPSS syntax: a beginner's guide Jacqueline Collier Using SPSS syntax: a beginner's guide Sage Pages: 216 £24.99 9781412922180 1412922186 [Formula: see text].

Science.gov (United States)

2011-01-21

As someone who is comfortable with analysing data in SAS using coding language, it is perplexing that I run from the use of syntax in SPSS. But, my apprehension has subsided with the Collier's guide. Syntax command can automate processes, increase reproducibility and give the user broader access to features otherwise unavailable in SPSS.

Publication Rates of Social and Administrative Sciences Pharmacy Faculty in Non-Research Intensive Pharmacy Schools.

Science.gov (United States)

Weathers, Trenna; Unni, Elizabeth

2018-04-01

Objective. To assess the level of publication rates from 2011 through 2015 by Social and Administrative Sciences (SAS) faculty at non-research intensive pharmacy schools. Methods. The Web of Science database was searched using faculty names identified from the American Association of Colleges of Pharmacy (AACP) faculty and professional staff roster. Publication rates of SAS faculty were calculated and compared using several demographic subcategories such as public/private school, part of an academic health center, schools with PhD program, funding status, etc. Results. The 208 SAS faculty members from 59 colleges contributed to 478 publications with a mean of 95.6 publications per year and 1.62 publications per institution per year. The number of publications increased 45% over the five years from 67 publications in 2011 to 122 in 2015.The average number of publications was 0.92 per year per SAS faculty compared to 0.82 publications per year per faculty from other basic pharmaceutical sciences divisions. The most commonly published research was research articles in the area of scholarship of teaching and learning. The significant predictors of publications were being part of an academic health center, having a PhD program, and higher percent of faculty members who are SAS faculty. Conclusion. Despite being affiliated with institutions with missions less targeted on research, this study showed SAS faculty members at non-research intensive institutions consistently contribute to published literature. Further studies are needed to examine reasons for the lack of publishing by almost half of the SAS faculty and ways to increase research and publication in the field of SAS.

Modification of solid-state property of sulfasalazine by using the supercritical antisolvent process

Science.gov (United States)

Wu, Wei-Yi; Su, Chie-Shaan

2017-02-01

In this study, the supercritical antisolvent (SAS) process was used to recrystallize an active pharmaceutical ingredient, sulfasalazine, to modify the solid-state properties including particle size, crystal habit and polymorphic form. Supercritical CO2 and tetrahydrofuran were used as the antisolvent and solvent, respectively. SAS results obtained from different operating temperatures (35, 45, 55 and 65 °C) were compared and discussed. The results indicate that at 55 °C, spherical sulfasalazine crystals were produced and that their mean particle size was micronized to approximately 1 μm. In addition, according to the analytical results of powder X-ray diffractometry (PXRD), a novel polymorphic form of sulfasalazine was obtained after SAS. Furthermore, the spectroscopic and thermal behavior of produced sulfasalazine crystals were also studied by Fourier transform infrared spectrometry (FTIR), differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA). Finally, SAS results obtained from different operating temperature was discussed on the basis of the mixture critical point (MCP) of CO2 and tetrahydrofuran. Operation at slightly higher than the MCP is favorable for recrystallization of sulfasalazine through SAS. These results demonstrate that the SAS process is an efficient tool for controlling and modifying the solid-state property of sulfasalazine.

Specific Consideration on Superior Performance and Evaluation Methods of Polymer-housed Surge Arresters

Science.gov (United States)

Ishizaki, Yoshihiro; Kobayashi, Misao; Suzuki, Hironori; Futagami, Koichi

It is very suitable to select the polymer materials for the housings of surge arresters (SAs), because the polymer materials are generally soft and light weight. Therefore, many kinds of polymer-housed SAs using various polymer materials have been developed, and expanding into many countries. Considering these backgrounds, the JEC technical report (JEC-TR) 23002-2008; polymer-housed surge arrester(1) has been established based on the existent relevant standards of arresters, such as JEC-2371-2003; Insulator-housed surge arresters(2) and IEC 60099-4 Edition 2.2, Metal-oxide surge arresters (MOSAs) without gaps for a.c. systems(3) in order to introduce the technology and provide a common guide for testing of polymer-housed SAs. According as the JEC-TR, the various new applications of the polymer-housed SAs, which are caused by superior advantages such as compact, light weight, safe failure mode, anti-seismic performance, anti-pollution performance and cost efficiency design, have been realized recently in Japan. Therefore, this paper gives specific consideration on the superior performance of the polymer-housed SAs and the evaluation methods of the polymer-housed SAs, because there are some issues in the existent standards to be solved.

Clinical symptoms of sleep apnea syndrome and automobile accidents

DEFF Research Database (Denmark)

Haraldsson, P O; Carenfelt, C; Diderichsen, Finn

1990-01-01

Patients with clinical features of sleep apnea syndrome (SAS) and self-reported sleep spells at the wheel do poorly in simulated monotonous driving. To evaluate whether drivers with defined symptoms of SAS (heavy snoring, sleep disturbances and daytime sleepiness) compensate in real traffic...... by careful driving or not, the rate of car accidents over a 5-year period was investigated. A questionnaire was addressed to 140 patients with and 142 controls without symptoms associated to SAS. Seventy-three of the patients had a complete triad of SAS-associated symptoms. Fifty-two percent...... with a complete triad of symptoms of SAS compared to controls (p less than 0.001). When corrected for mileage driven, the total number of single-car accidents was almost 12 times higher among patients with sleep spells whilst driving, compared to controls (p less than 0.001). It is concluded that drivers...

Structural basis for (p)ppGpp synthesis by thesmall alarmone synthetase RelP

DEFF Research Database (Denmark)

Manav, Melek Cemre; Beljantseva, Jelena; Bojer, Martin S

2018-01-01

Q (SAS1) and RelP (SAS2). InBacillus subtilis, RelQ (SAS1) was shown to form a tetramer that is activated by pppGpp and inhibited by single-stranded RNA, but the structural and functional regulation of RelP (SAS2) is unexplored. Here, we present crystal structures ofS. aureusRelP in two major functional......The stringent response is a global reprogramming of bacterial physiology that renders cells more tolerant to antibiotics and induces virulence gene expression in pathogens in response to stress. This process is driven by accumulation of the intracellular alarmone guanosine-5'-di(tri)phosphate-3...

High polarization purity operation of 99% in 9xx-nm broad stripe laser diodes

Science.gov (United States)

Morohashi, Rintaro; Yamagata, Yuji; Kaifuchi, Yoshikazu; Tada, Katsuhisa; Nogawa, Ryozaburo; Yamada, Yumi; Yamaguchi, Masayuki

2018-02-01

Polarization characteristics of self-aligned stripe (SAS) laser diodes (LDs) and Ridge-LDs are investigated to realize highly efficient polarization beam combined (PBC) LD modules. Vertical layers of both lasers are designed identically. Near field patterns (NFP) of TM polarization for the Ridge-LD showed peaks at the side edges, as expected by the strain simulation. On the other hand, SAS-LD showed a relatively flat and weak profile. Polarization purity (ITE/ (ITE+ITM)) of SAS-LDs exceeds 99%, while those of the Ridge-LDs are as low as 96%. It is confirmed that our SAS-LDs are suitable sources for PBC with low power loss.

[Professional ethics, an essential element of nursing practice].

Science.gov (United States)

Debout, Christophe

2017-09-01

The context of contemporary practice exposes nurses to a wide variety of ethical dilemmas. In 1978, nurses were granted autonomy within the scope of their therapeutic role but there was also a need for the profession to embark on a new stage by introducing a code of ethics. It was not until 2016 that the first code of ethics for nurses was published in France, 63 years after the publication of a code by the International Council of Nurses. Copyright © 2017. Published by Elsevier Masson SAS.

Does the StartReact Effect Apply to First-Trial Reactive Movements?

Directory of Open Access Journals (Sweden)

Katrin Sutter

Full Text Available StartReact is the acceleration of reaction time by a startling acoustic stimulus (SAS. The SAS is thought to release a pre-prepared motor program. Here, we investigated whether the StartReact effect is applicable to the very first trial in a series of repeated unpractised single-joint movements.Twenty healthy young subjects were instructed to perform a rapid ankle dorsiflexion movement in response to an imperative stimulus. Participants were divided in two groups of ten. Both groups performed 17 trials. In one group a SAS (116 dB was given in the first trial, whereas the other group received a non-startling sound (70 dB as the first imperative stimulus. In the remaining 16 trials, the SAS was given as the imperative stimulus in 25% of the trials in both groups. The same measurement was repeated one week later, but with the first-trial stimuli counterbalanced between groups.When a SAS was given in the very first trial, participants had significantly shorter onset latencies compared to first-trial responses to a non-startling stimulus. Succeeding trials were significantly faster compared to the first trial, both for trials with and without a SAS. However, the difference between the first and succeeding trials was significantly larger for responses to a non-startling stimulus compared to responses triggered by a SAS. SAS-induced acceleration in the first trial of the second session was similar to that in succeeding trials of session 1.The present results confirm that the StartReact phenomenon also applies to movements that have not yet been practiced in the experimental context. The excessive SAS-induced acceleration in the very first trial may be due to the absence of integration of novel context-specific information with the existing motor memory for movement execution. Our findings demonstrate that StartReact enables a rapid release of motor programs in the very first trial also without previous practice, which might provide a behavioural

Configuration Entropy Calculations for Complex Compounds Technetium

International Nuclear Information System (INIS)

Muhayatun; Susanto Imam Rahayu; Surdia, N.M.; Abdul Mutalib

2002-01-01

Recently, the study of technetium complexes is rapidly increasing, due to the benefit of 99m Tc complexes (one of Tc nuclear isomers), which are widely used for diagnostics. Study of the structure-stability relationship of Tc complexes based on solid angle has been done by Kung using a Solid Angle Factor Sum (SAS). The SAS is hypothesized to be related to stability. SAS has been used by several researchers either for synthesis or designing the reaction route of the Tc complex formation and predicting the geometry of complex structures. Although the advantages of the SAS were very gratifying, but the model does not have the theoretical basis which is able to explain the correlation of steric parameters to physicochemical properties of complexes especially to those connected to a complex's stability. To improve the SAS model, in this research the model was modified by providing a theoretical basis for SAS. The results obtained from the correlation of the SAS value to the thermodynamic stability parameters of simple complexes show the values to have a similar trend as the standard entropy (S 0 ). The entropy approximation model was created by involving some factors which are not used in Kung's model. Entropy optimization to the bond length (ML) has also been done to several complexes. The calculations of SAS value using the calculated R for more than 100 Tc complexes provide a normalized mean value of 0.8545 ± 0.0851 and have similar curve profiles as those of Kung's model. The entropy value can be obtained by multiplying the natural logarithm of the a priori degeneracy of a certain distribution (Ω) and the Boltzmann constant. The results of Ω and In Ω of the Tc complexes have a narrow range. The results of this research are able to provide a basic concept for the SAS to explain the structure-stability relationship and to improve Kung's model. (author)

[Commitment at the heart of the nursing profession].

Science.gov (United States)

Lecointre, Brigitte

2017-12-01

Although it is a free choice and appears paradoxical, the choice to be a nurse is binding. In keeping with its Code of Ethics, the nursing profession demands an ethical, social, political and collective commitment that we cannot shy away from or we will fail to fulfil our obligations. Copyright © 2017. Published by Elsevier Masson SAS.

Comparison of peak flow velocity through the left ventricular outflow tract and effective orifice area indexed to body surface area in Golden Retriever puppies to predict development of subaortic stenosis in adult dogs.

Science.gov (United States)

Javard, Romain; Bélanger, Marie-Claude; Côté, Etienne; Beauchamp, Guy; Pibarot, Philippe

2014-12-15

To evaluate the usefulness of Doppler-derived peak flow velocity through the left ventricular outflow tract (LVOT Vmax) and effective orifice area indexed to body surface area (EOAi) in puppies to predict development of subaortic stenosis (SAS) in the same dogs as adults. Prospective, longitudinal, observational study. 38 Golden Retrievers. Cardiac auscultation and echocardiography were performed on 2- to 6-month-old puppies, then repeated at 12 to 18 months. Subaortic stenosis was diagnosed when LVOT Vmax was ≥ 2.3 m/s in adult dogs with left basilar systolic murmurs. All puppies with EOAi 2.3 m/s in puppyhood was 63% sensitive and 100% specific for SAS in adulthood. In puppies, LVOT Vmax was more strongly associated with a future diagnosis of SAS (area under the curve [AUC], 0.89) than was EOAi (AUC, 0.80). In puppies, the combination of LVOT Vmax and EOAi yielded slightly higher sensitivity (69%) and specificity (100%) for adult SAS than did LVOT Vmax alone. In unaffected and affected dogs, LVOT Vmax increased significantly from puppyhood to adulthood but EOAi did not. In Golden Retriever puppies, LVOT Vmax > 2.3 m/s and EOAi < 1.46 cm(2)/m(2) were both associated with a diagnosis of SAS at adulthood. The combination of these 2 criteria may result in higher sensitivity for SAS screening. Unlike LVOT Vmax, EOAi did not change during growth in either unaffected Golden Retrievers or those with SAS.

Lithography-Free Fabrication of Large Area Subwavelength Antireflection Structures Using Thermally Dewetted Pt/Pd Alloy Etch Mask

Directory of Open Access Journals (Sweden)

Kang Jeong-Jin

2009-01-01

Full Text Available Abstract We have demonstrated lithography-free, simple, and large area fabrication method for subwavelength antireflection structures (SAS to achieve low reflectance of silicon (Si surface. Thin film of Pt/Pd alloy on a Si substrate is melted and agglomerated into hemispheric nanodots by thermal dewetting process, and the array of the nanodots is used as etch mask for reactive ion etching (RIE to form SAS on the Si surface. Two critical parameters, the temperature of thermal dewetting processes and the duration of RIE, have been experimentally studied to achieve very low reflectance from SAS. All the SAS have well-tapered shapes that the refractive index may be changed continuously and monotonously in the direction of incident light. In the wavelength range from 350 to 1800 nm, the measured reflectance of the fabricated SAS averages out to 5%. Especially in the wavelength range from 550 to 650 nm, which falls within visible light, the measured reflectance is under 0.01%.

Statin-Associated Side Effects.

Science.gov (United States)

Thompson, Paul D; Panza, Gregory; Zaleski, Amanda; Taylor, Beth

2016-05-24

Hydroxy-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitors or statins are well tolerated, but associated with various statin-associated symptoms (SAS), including statin-associated muscle symptoms (SAMS), diabetes mellitus (DM), and central nervous system complaints. These are "statin-associated symptoms" because they are rare in clinical trials, making their causative relationship to statins unclear. SAS are, nevertheless, important because they prompt dose reduction or discontinuation of these life-saving mediations. SAMS is the most frequent SAS, and mild myalgia may affect 5% to 10% of statin users. Clinically important muscle symptoms, including rhabdomyolysis and statin-induced necrotizing autoimmune myopathy (SINAM), are rare. Antibodies against HMG-CoA reductase apparently provoke SINAM. Good evidence links statins to DM, but evidence linking statins to other SAS is largely anecdotal. Management of SAS requires making the possible diagnosis, altering or discontinuing the statin treatment, and using alternative lipid-lowering therapy. Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

Effect of some colloid surfactants on spectrophotometric characteristics of metal chelates with chromophore organic reagents

International Nuclear Information System (INIS)

Chernova, R.K.

1977-01-01

Theoretical regularities and prospects of using surface active substances (SAS) in spectrophotometric determination of metal ions (including ions of rare-earth elements, transition metals, Be(3)) with chromophore chelating reagents were investigated. The chromophore reagents investigated were pyrocatechol violet, phenolcarboxylic acids of the triarylmethane series, fluorones, phthalexones and azo-compounds. As SAS certain long-chain quaternary ammonium and pyridinium salts (LQAS) were employed. From the results reported it follows that the introduction of LQAS in the system of Mesup(n+)-chromophore reagent is a rather effective method of enhancing the contrast rendition and, in some cases, the sensitivity and selectivity of the reagents. Explanations are suggested as to the factors which cause the changes observed in the contrast of the reactions in the presence of SAS; the underlying phenomena are the ligand-ligand interactions between the organic reagents and SAS and solubilization processes of the reaction products by the micelles of SAS

Attitudes and barriers in implementing the environmental management system in a primary health care center Actitudes y barreras en la implantación del Sistema de Gestión Medioambiental en un centro de salud

Directory of Open Access Journals (Sweden)

Jaime Ángel Gata Díaz

2007-12-01

Full Text Available Objective: Identify attitudes and analyze the barriers perceived by those responsible for the implementation of SIGA-SAS in the primary health care centers of Distrito Sanitario Jaén.Methods: Between the nine primary health care centers that assisted a population more than 6000 users, were selected four professional with management tasks. We carried out an interview using a standardized questionnaire with 18 open questions, before conducting the interview, a small talk was given training and or delivered an informative documentation about SIGA-SAS. The interviews were recorded and transcribed in order to further analyze the speech in front of each professional to implement the SIGA-SAS.Results: Among the key findings on attitudes stressing the importance of the Managing Director of SAS to succeed in implementing the SIGA-SAS, and must rely on the actions of continuous improvement and active listening to the professionals. In addition there was also a clear consensus on the importance of the Distrito Sanitario Jaén and the ZBS management team to lead the implementation, defining objectives, setting tasks and delegating res- ponsibilities.Conclusions: The success of SIGA-SAS implementing should be based on three pillars, reinforcing the positive attitudes of the health professionals team working in the primary health care centers, the training of individuals with regard to the SIGA-SAS and the careful scheduling of the sequence of tasks to carry at all times.Objetivo: Identificar las actitudes y analizar las barreras percibidas por los responsables de la implantación del Sistema Integral de Gestión Ambiental, del Servicio Andaluz de Salud (SIGA-SAS, en los centros de salud del Distrito Sanitario Jaén.Material y métodos: De los nueve centros de salud, del Distrito Sanitario Jaén, con una población asistida superior a 6.000 habitantes, fueron seleccionados cuatro profesionales con funciones de gestión. Se llevó a cabo una entrevista

Susan J. Slaughter, Lora D. Delwiche, The Little SAS Book for Enterprise Guide 4.1 et James B. Davis, Statistics using SAS Enterprise Guide

OpenAIRE

2010-01-01

Le logiciel SAS® (Statistical Analysis System) est un logiciel d’analyse statistique et économétrique de référence en économie industrielle ; il permet de gérer de grandes bases de données informatiques indépendamment de leur format ou de leur plate-forme de résidence, de réaliser quasiment tous les traitements économétriques sur ces données, et de mettre en forme les résultats. Un obstacle à son utilisation a souvent résidé pour beaucoup dans la relative complexité des outils de programmatio...

Small-angle neutron scattering technique in liquid crystal studies

International Nuclear Information System (INIS)

Shahidan Radiman

2005-01-01

The following topics discussed: general principles of SAS (Small-angle Neutron Scattering), liquid crystals, nanoparticle templating on liquid crystals, examples of SAS results, prospects of this studies

Validation and Reliability of the Korean Version of the Sport Anxiety Scale-2

Directory of Open Access Journals (Sweden)

Cho Seongkwan

2018-03-01

Full Text Available The main purpose of the present study was to examine the validation and reliability of the Korean version of the Sport Anxiety Scale (SAS-2Kr by evaluating its factorial invariance across gender. A total of 303 Korean collegiate athletes (198 males and 105 females from 9 sports participated in the study, and they completed the demographic questionnaire and the SAS-2Kr containing 15 items to measure multidimensional trait anxiety and individual differences in the cognitive and somatic anxiety experienced by athletes. The results of this study indicated that the construct validity in the SAS-2Kr was well established in that the values of the standardized factor loadings, composite reliability, and average variance extracted values were above the recommended cutoff points. The multiple-sample confirmatory factor analyses showed the SAS-2Kr could be generalizable across gender in college samples. The results also indicated that the SAS-2Kr supported the original 3-factor model of SAS-2 in English consisting of somatic anxiety, worry, and concentration disruption, and thus this study provides useful information for researchers to understand the athletes’ tendency to experience anxiety reactions in sport situations. Suggestions for future research on competitive trait anxiety are provided in the discussion section.

Intramyocardial arterial narrowing in dogs with subaortic stenosis.

Science.gov (United States)

Falk, T; Jönsson, L; Pedersen, H D

2004-09-01

Earlier studies have described intramyocardial arterial narrowing based on hyperplasia and hypertrophy of the vessel wall in dogs with subaortic stenosis (SAS). In theory, such changes might increase the risk of sudden death, as they seem to do in heart disease in other species. This retrospective pathological study describes and quantifies intramyocardial arterial narrowing in 44 dogs with naturally occurring SAS and in eight control dogs. The majority of the dogs with SAS died suddenly (n=27); nine had died or been euthanased with signs of heart failure and eight were euthanased without clinical signs. Dogs with SAS had significantly narrower intramyocardial arteries (Pdogs. Male dogs and those with more severe hypertrophy had more vessel narrowing (P=0.02 and P=0.02, respectively), whereas dogs with dilated hearts had slightly less pronounced arterial thickening (P=0.01). Arterial narrowing was not related to age, but fibrosis increased with age (P=0.047). Dogs that died suddenly did not have a greater number of arterial changes than other dogs with SAS. This study suggests that most dogs with SAS have intramyocardial arterial narrowing and that the risk of dying suddenly is not significantly related to the overall degree of vessel obliteration.

Applications of Spatial Data Using Business Analytics Tools

Directory of Open Access Journals (Sweden)

Anca Ioana ANDREESCU

2011-12-01

Full Text Available This paper addresses the possibilities of using spatial data in business analytics tools, with emphasis on SAS software. Various kinds of map data sets containing spatial data are presented and discussed. Examples of map charts illustrating macroeconomic parameters demonstrate the application of spatial data for the creation of map charts in SAS Enterprise Guise. Extended features of map charts are being exemplified by producing charts via SAS programming procedures.

Occurrence of sulfonamide residues along the Ebro River basin: removal in wastewater treatment plants and environmental impact assessment.

Science.gov (United States)

García-Galán, M Jesús; Díaz-Cruz, M Silvia; Barceló, Damià

2011-02-01

Sulfonamides (SAs) have become one of the antibiotic families most frequently found in all kind of environmental waters. In the present work, the presence of 16 SAs and one of their acetylated metabolites in different water matrices of the Ebro River basin has been evaluated during two different sampling campaigns carried out in 2007 and 2008. Influent and effluent samples from seven wastewater treatment plants (WWTPs), together with a total of 28 river water samples were analyzed by on-line solid phase extraction-liquid chromathography-tandem mass spectrometry (on-line SPE-LC-MS/MS). Sulfamethoxazole and sulfapyridine were the SAs most frequently detected in WWTPs (96-100%), showing also the highest concentrations, ranging from 27.2 ng L(-1) to 596 ng L(-1) for sulfamethoxazole and from 3.7 ng L(-1) to 227 ng L(-1) for sulfapyridine. Sulfamethoxazole was also the SA most frequently detected in surface waters (85% of the samples) at concentrations between 11 ng L(-1) and 112 ng L(-1). In order to assess the effectiveness of the wastewater treatment in degrading SAs, removal efficiencies in the seven WWTPs were calculated for each individual SA (ranging from 4% to 100%) and correlated to the corresponding hydraulic retention times or residence times of the SAs in the plants. SAs half-lives were also estimated, ranging from to 2.5 hours (sulfadimethoxine) to 128 h (sulfamethazine). The contribution of the WWTPs to the presence of SAs depends on both the load of SAs discharging on the surface water from the WWTP effluent but also on the flow of the receiving waters in the discharge sites and the dilution exerted; WWTP4 exerts the highest pressure on the receiving water course. Finally, the potential environmental risk posed by SAs was evaluated calculating the hazard quotients (HQ) to different non-target organisms in effluent and river water. The degree of susceptibility resulted in algae>daphnia>fish. Sulfamethoxazole was the only SA posing a risk to algae in

The effect of antibrowning agents on inhibition of potato browning, volatile organic compound profile, and microbial inhibition.

Science.gov (United States)

Mosneaguta, Ruslan; Alvarez, Valente; Barringer, Sheryl A

2012-11-01

Burbank and Norkotah potato slices were dipped into 3% sodium acid sulfate (SAS), citric acid (CA), sodium erythorbate (SE), malic acid (MA), sodium acid pyrophosphate (SAPP), or a combination of SAS-CA-SE. Browning by polyphenol oxidase (PPO) obtained from potato extract with 0.04 to 0.016 g/mL of antibrowning solutions at pH 2.0 to 6.9 were measured by UV-Vis spectroscopy. The color of slices dipped in antibrowning solutions at pHs 2 to 7 and stored at 4 °C for 15 d was measured every 5 d by colorimeter. Headspace analysis of volatiles in raw and cooked potato samples was performed by selected ion flow tube mass spectrometer (SIFT-MS) and soft independent modelling by class analogy (SIMCA) analysis of the calculated odor activity values (OAV) determined interclass distances. Microbial growth was measured at 15 d. At unadjusted pHs (1.1 to 7.1), the PPO browning of the control and samples with SAPP was not significantly different, SAS, CA, and MA produced some inhibition and SE and SAS-CA-SE prevented browning. At pH 5 to 7, only SE and SAS-CA-SE were effective browning inhibitors. Based on the color of potato slices, SE was the most effective at pH 2 to 7, but SAS was most effective at unadjusted pH. Cooking increased volatile levels in the treated potatoes and decreased differences between volatile profiles. Differences between cooked samples may not be noticeable by the consumer because volatiles with high discriminating powers have low OAVs. SAS, CA, and SAS-CA-SE treatments inhibited microbial growth but SAPP, control, and SE did not, most likely due to pH. Antibrowning agents inhibit polyphenol oxidase, increasing shelf life and consumer acceptability of processed raw potato products by preserving the color. Their effectiveness was shown to be mainly due to a pH effect, except SE, which was not pH dependent. MA, CA, and SAS-CA-SE are better acidulants for inhibition of color change as well as growth of spoilage bacteria, yeast, and mold than SAPP, the

Holistic life-span health outcomes among elite intercollegiate student-athletes.

Science.gov (United States)

Sorenson, Shawn C; Romano, Russell; Scholefield, Robin M; Martin, Brandon E; Gordon, James E; Azen, Stanley P; Schroeder, E Todd; Salem, George J

2014-01-01

Competitive sports are recognized as having unique health benefits and risks, and the effect of sports on life-span health among elite athletes has received increasing attention. However, supporting scientific data are sparse and do not represent modern athletes. To assess holistic life-span health and health-related quality-of-life (HRQL) among current and former National Collegiate Athletic Association student-athletes (SAs). Cross-sectional study. A large Division I university. Population-based sample of 496 university students and alumni (age 17-84 years), including SAs and an age-matched and sex-matched nonathlete (NA) control group. Participants completed anonymous, self-report questionnaires. We measured the Short-Form 12 (SF-12) physical and mental component HRQL scores and cumulative lifetime experience and relative risk of treatment for joint, cardiopulmonary, and psychosocial health concerns. Older alumni (age 43+ years) SAs reported greater joint health concerns than NAs (larger joint summary scores; P = .04; Cohen d = 0.69; probability of clinically important difference [pCID] = 77%; treatment odds ratio [OR] = 14.0, 95% confidence interval [CI] = 1.6, 126). Joint health for current and younger alumni SAs was similar to that for NAs. Older alumni reported greater cardiopulmonary health concerns than younger alumni (summary score P students (P 99.5%; OR = 7.1, 95% CI = 3.3, 15), but the risk was similar for SAs and NAs. Current SAs demonstrated evidence of better psychosocial health (summary score P = .006; d = -0.52; pCID = 40%) and mental component HRQL (P = .008; d = 0.50; pCID = 48%) versus NAs but similar psychosocial treatment odds (OR = 0.87, 95% CI = 0.39, 1.9). Psychosocial health and mental component HRQL were similar between alumni SAs and NAs. No differences were observed between SAs and NAs in physical component HRQL. The SAs demonstrated significant, clinically meaningful evidence of greater joint health concerns later in life, comparable

STOCHASTIC HUMAN EXPOSURE AND DOSE SIMULATION MODEL FOR THE WOOD PRESERVATIVE SCENARIO (SHEDS-WOOD), VERSION 2 MODEL SAS CODE

Science.gov (United States)

Concerns have been raised regarding the safety of young children contacting arsenic and chromium residues while playing on and around Chromated Copper Arsenate (CCA) treated wood playground structures and decks. Although CCA registrants voluntarily canceled treated wood for resi...

Abnormal hyperintensity within the subarachnoid space evaluated by fluid-attenuated inversion-recovery MR imaging: a spectrum of central nervous system diseases

International Nuclear Information System (INIS)

Maeda, M.; Sakuma, H.; Takeda, K.; Yagishita, A.; Yamamoto, T.

2003-01-01

A variety of central nervous system (CNS) diseases are associated with abnormal hyperintensity within the subarachnoid space (SAS) by fluid-attenuated inversion-recovery (FLAIR) MR imaging. Careful attention to the SAS can provide additional useful information that may not be available with conventional MR sequences. The purpose of this article is to provide a pictorial essay about CNS diseases and FLAIR images with abnormal hyperintensity within the SAS. We present several CNS diseases including subarachnoid hemorrhage, meningitis, leptomeningeal metastases, acute infarction, and severe arterial occlusive diseases such as moya-moya disease. We also review miscellaneous diseases or normal conditions that may exhibit cerebrospinal fluid hyperintensity on FLAIR images. Although the detection of abnormal hyperintensity suggests the underlying CNS diseases and narrows differential diagnoses, FLAIR imaging sometimes presents artifactual hyperintensity within the SAS that can cause the misinterpretation of normal SAS as pathologic conditions; therefore, radiologists should be familiar with such artifactual conditions as well as pathologic conditions shown as hyperintensity by FLAIR images. This knowledge is helpful in establishing the correct diagnosis. (orig.)

Validation of a Malay Version of the Smartphone Addiction Scale among Medical Students in Malaysia.

Science.gov (United States)

Ching, Siew Mooi; Yee, Anne; Ramachandran, Vasudevan; Sazlly Lim, Sazlyna Mohd; Wan Sulaiman, Wan Aliaa; Foo, Yoke Loong; Hoo, Fan Kee

2015-01-01

This study was initiated to determine the psychometric properties of the Smart Phone Addiction Scale (SAS) by translating and validating this scale into the Malay language (SAS-M), which is the main language spoken in Malaysia. This study can distinguish smart phone and internet addiction among multi-ethnic Malaysian medical students. In addition, the reliability and validity of the SAS was also demonstrated. A total of 228 participants were selected between August 2014 and September 2014 to complete a set of questionnaires, including the SAS and the modified Kimberly Young Internet addiction test (IAT) in the Malay language. There were 99 males and 129 females with ages ranging from 19 to 22 years old (21.7±1.1) included in this study. Descriptive and factor analyses, intra-class coefficients, t-tests and correlation analyses were conducted to verify the reliability and validity of the SAS. Bartlett's test of sphericity was significant (p addiction scale among medical students. This scale was shown to be reliable and valid in the Malay language.

2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update.

Science.gov (United States)

Trewhella, Jill; Duff, Anthony P; Durand, Dominique; Gabel, Frank; Guss, J Mitchell; Hendrickson, Wayne A; Hura, Greg L; Jacques, David A; Kirby, Nigel M; Kwan, Ann H; Pérez, Javier; Pollack, Lois; Ryan, Timothy M; Sali, Andrej; Schneidman-Duhovny, Dina; Schwede, Torsten; Svergun, Dmitri I; Sugiyama, Masaaki; Tainer, John A; Vachette, Patrice; Westbrook, John; Whitten, Andrew E

2017-09-01

In 2012, preliminary guidelines were published addressing sample quality, data acquisition and reduction, presentation of scattering data and validation, and modelling for biomolecular small-angle scattering (SAS) experiments. Biomolecular SAS has since continued to grow and authors have increasingly adopted the preliminary guidelines. In parallel, integrative/hybrid determination of biomolecular structures is a rapidly growing field that is expanding the scope of structural biology. For SAS to contribute maximally to this field, it is essential to ensure open access to the information required for evaluation of the quality of SAS samples and data, as well as the validity of SAS-based structural models. To this end, the preliminary guidelines for data presentation in a publication are reviewed and updated, and the deposition of data and associated models in a public archive is recommended. These guidelines and recommendations have been prepared in consultation with the members of the International Union of Crystallography (IUCr) Small-Angle Scattering and Journals Commissions, the Worldwide Protein Data Bank (wwPDB) Small-Angle Scattering Validation Task Force and additional experts in the field.

Optimization of medium composition for apple rootstocks

African Journals Online (AJOL)

User

2011-05-02

May 2, 2011 ... Key words: Apple rootstocks, medium composition, multiplication rate, plant growth regulators (PGRs). ... be extrapolated with the same success for another .... Analysis System (SAS) software program (SAS Institute Inc. 1999).

SAS-085 C2 Agility Model Validation Using Case Studies

Science.gov (United States)

2013-06-01

civilians who sought refuge with UNAMIR. As the slaughter continued, UN peacekeeping forces stood by since they are forbidden to intervene, as this would...Cyber Common Operating Picture ( COP ) to help them analyze and respond to the challenge. The SSA and Cyber COP was created almost on the fly in a

SAS2: A Guide to Collaborative Inquiry and Social Engagement ...

International Development Research Centre (IDRC) Digital Library (Canada)

2008-01-01

Jan 1, 2008 ... It also provides detailed instructions on how to integrate and ground collaborative inquiry in the projects, plans, evaluations and activities of multiple stakeholders. Part 2 presents a selection of techniques for collaborative inquiry and examples of real-life applications in South Asia and Latin America.

Plan de empresa "Mantenimientos Inmobiliarios de Occidente S.A.S.

OpenAIRE

Velasquez Arbelaez, Luz Stella; Espinosa Buitrago, Angelo

2011-01-01

En este estudio se presenta un análisis de factibilidad para crear una empresa prestadora de servicios de mantenimiento en unidades residenciales en la ciudad de Cali, aprovechando el crecimiento del sector residencial en la zona sur de la ciudad. El portafolio va dirigido especialmente a los administradores de unidades residenciales y a copropietarios que deseen realizar alguna labor de mantenimiento en sus viviendas, quienes podrán beneficiarse de un servicio de manteni...

'N PERD VAN 'N ANDER KLEUR SAS SOMERSET (1942-1986)

African Journals Online (AJOL)

Naas die bekende vlootvaartuie soos byvoorbeeld duikbote, vliegdekskepe en missieldraende aanvalsvaartuie, is daar in die meeste vlote ter wereld ander vaartuigtipes wat soms 'n groot deel van hul leeftyd hawegebonde is, maar nogtans waardevolle diens ten behoewe van ander skepe of ter beskerming van hawens ...

Understanding Self-regulation Behaviors in South Asians With Coronary Artery Disease: A Mixed-Methods Study.

Science.gov (United States)

Jiwani, Rozmin B; Cleveland, Lisa M; Patel, Darpan I; Virani, Salim S; Gill, Sara L

South Asians (SAs) have a well-documented risk for mortality related to coronary artery disease (CAD). However, there is a lack of evidence to guide the implementation and dissemination of primary and secondary interventions to control and deter progression of CAD in SAs. The aim of this study is to explore and describe self-regulation behaviors in SAs with CAD using Leventhal's Common Sense Model. In this mixed-methods study, quantitative data were collected using 3 survey questionnaires (demographics, Illness Perception Questionnaire-Revised, and Coping/Self-Regulation Behaviors). Before completing the surveys, a subset of the sample (n = 20) participated in individual face-to-face or telephone interviews. A total of 102 SAs were enrolled (age, 53.5 ± 9.98 years). On average, participants rated themselves high (63 ± 3.06) on negative perceptions. In addition, they discussed desi diet, stress, a lack of physical activity, ignoring symptoms, and kismet (fate) as the most important perceived causes of their CAD. Most of the participants modified their lifestyle after their CAD event. Participants expressed regret for not having changed their lifestyle earlier when they were experiencing early symptoms of their CAD. Findings from this study enhance the understanding of self-regulation behaviors of SAs with CAD. Ultimately, these findings will inform the development and implementation of targeted interventions that address culture-specific lifestyle modification for SAs with CAD.

Is history of suicidal behavior related to social support and quality of life in outpatients with bipolar I disorder?

Science.gov (United States)

Studart, Paula; Galvão-de Almeida, Amanda; Bezerra-Filho, Severino; Caribé, André; Reis Afonso, Nayanne; Daltro, Carla; Miranda-Scippa, Ângela

2016-12-30

Bipolar disorder (BD) affects the social functioning and quality of life (QoL) of its patients. This study aimed to investigate whether there is an association between social support (SS), and suicidal behavior in BD I patients compared to healthy controls; secondarily, we evaluated the influence of QoL on those variables. A total of 119 euthymic outpatients with BD I, 46 of whom had attempted suicide (SAs) and 73 who had not (non-SAs), were compared to 63 healthy controls, through the Medical Outcomes Study Social Support Scale and World Health Organization's Quality of Life Instrument. No differences were noted in SS and QoL between SAs and non-SAs. Compared to healthy controls, non-SAs showed lower values in the positive social interaction domain of SS, and the patients, as a whole, showed lower values in affectionate and positive social interaction domains of SS. Compared to healthy controls, SAs had lower values in the environmental domain of QoL, and the patients, as a whole, had lower values in the environmental, social, and psychological domains of QoL. There was positive correlation between SS and QoL. Although BD is a disabling disease, patients receive inadequate SS. Interventions that may alter the SS in these patients should be investigated. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Investigation of the thermal mixing in a T-junction flow with different SRS approaches

Energy Technology Data Exchange (ETDEWEB)

Gritskevich, M.S., E-mail: gritskevich@ymail.com [St. Petersburg State Polytechnical University, 195251 St. Petersburg (Russian Federation); Garbaruk, A.V. [St. Petersburg State Polytechnical University, 195251 St. Petersburg (Russian Federation); Frank, Th.; Menter, F.R. [Software Development Department, ANSYS, 83714 Otterfing (Germany)

2014-11-15

Highlights: • Global (SAS, DDES) and zonal (ELES-WMLES) models are compared for the T-junction flow. • All the models accurately predict mean, RMS, and spectral quantities. • ELES-WMLES approach yields very good results independent of the advection scheme. • SAS and the DDES models are slightly less accurate. • SAS depends on the advection scheme. - Abstract: An investigation of different turbulence Scale-Resolving Simulation (SRS) modeling approaches for the flow in a T-junction has been conducted using the Scale-Adaptive Simulation (SAS), the Delayed Detached Eddy Simulation (DDES) and the Embedded Large Eddy Simulation (ELES) methods. The results show that all models are able to accurately predict mean and RMS velocity profiles and velocity spectra, when are used in combination with a low dissipation advection scheme. However, when a slightly more dissipative scheme is used, the SAS model yields less accurate results, indicating that this flow does not produce a strong enough flow instability to allow the safe application of this model. The DDES and the ELES models show less sensitivity to the numerical setting compared to the SAS model. The main goal of the study is the accurate prediction of heat transfer on the walls in the mixing zone. In that respect, the ELES method produces the most consistent agreement with the experimental data.

Antibiotic Pollution in Marine Food Webs in Laizhou Bay, North China: Trophodynamics and Human Exposure Implication.

Science.gov (United States)

Liu, Sisi; Zhao, Hongxia; Lehmler, Hans-Joachim; Cai, Xiyun; Chen, Jingwen

2017-02-21

Little information is available about the bioaccumulation and biomagnification of antibiotics in marine food webs. Here, we investigate the levels and trophic transfer of 9 sulfonamide (SA), 5 fluoroquinolone (FQ), and 4 macrolide (ML) antibiotics, as well as trimethoprim in nine invertebrate and ten fish species collected from a marine food web in Laizhou Bay, North China in 2014 and 2015. All the antibiotics were detected in the marine organisms, with SAs and FQs being the most abundant antibiotics. Benthic fish accumulated more SAs than invertebrates and pelagic fish, while invertebrates exhibited higher FQ levels than fish. Generally, SAs and trimethoprim biomagnified in the food web, while the FQs and MLs were biodiluted. Trophic magnification factors (TMF) were 1.2-3.9 for SAs and trimethoprim, 0.3-1.0 for FQs and MLs. Limited biotransformation and relatively high assimilation efficiencies are the likely reasons for the biomagnification of SAs. The pH dependent distribution coefficients (log D) but not the lipophilicity (log K OW ) of SAs and FQs had a significant correlation (r = 0.73; p < 0.05) with their TMFs. Although the calculated estimated daily intakes (EDI) for antibiotics suggest that consumption of seafood from Laizhou Bay is not associated with significant human health risks, this study provides important insights into the guidance of risk management of antibiotics.

Quantities of uranium-235 buried in disposal boxes, 1985--1991

International Nuclear Information System (INIS)

Cook, J.R.

1991-01-01

IWT was asked by J. R. Schornhorst of NPSR to determine the distribution of the quantity of enriched uranium per disposal box (B-25) of the years 1985--1991 to provide input to an uptake of the E Area Safety Analysis. This information was considered important since the issue of criticality is an important concern in safety analyses. Information found in the COBRA data base shows no disposal containers exceeded 100 grams of U-235. The COBRA data base was queried in a two-step process. First a short program in the NATURAL language was used to retrieve all records beginning with January 1983 having a Burial Code of less than 4, indicating low-level waste disposed in trenches. These records were then passed to a temporary storage file and read into a program written in Statistical Analysis System (SAS) language. SAS was used to eliminate waste from the Naval Fuel Facility, which will not operate in the future, and to sort the records in order of increasing amounts of U-235. The SAS procedure FREQ was then used to produce a cumulative frequency distribution of grams of U-235. A total of 53,198 packages were disposed of during this time period, 277 of which contained U-235. The programs used and resulting output are attached as Appendix I

The Fusarium graminearum Histone Acetyltransferases Are Important for Morphogenesis, DON Biosynthesis, and Pathogenicity

Directory of Open Access Journals (Sweden)

Xiangjiu Kong

2018-04-01

Full Text Available Post-translational modifications of chromatin structure by histone acetyltransferase (HATs play a central role in the regulation of gene expression and various biological processes in eukaryotes. Although HAT genes have been studied in many fungi, few of them have been functionally characterized. In this study, we identified and characterized four putative HATs (FgGCN5, FgRTT109, FgSAS2, FgSAS3 in the plant pathogenic ascomycete Fusarium graminearum, the causal agent of Fusarium head blight of wheat and barley. We replaced the genes and all mutant strains showed reduced growth of F. graminearum. The ΔFgSAS3 and ΔFgGCN5 mutant increased sensitivity to oxidative and osmotic stresses. Additionally, ΔFgSAS3 showed reduced conidia sporulation and perithecium formation. Mutant ΔFgGCN5 was unable to generate any conidia and lost its ability to form perithecia. Our data showed also that FgSAS3 and FgGCN5 are pathogenicity factors required for infecting wheat heads as well as tomato fruits. Importantly, almost no Deoxynivalenol (DON was produced either in ΔFgSAS3 or ΔFgGCN5 mutants, which was consistent with a significant downregulation of TRI genes expression. Furthermore, we discovered for the first time that FgSAS3 is indispensable for the acetylation of histone site H3K4, while FgGCN5 is essential for the acetylation of H3K9, H3K18, and H3K27. H3K14 can be completely acetylated when FgSAS3 and FgGCN5 were both present. The RNA-seq analyses of the two mutant strains provide insight into their functions in development and metabolism. Results from this study clarify the functional divergence of HATs in F. graminearum, and may provide novel targeted strategies to control secondary metabolite expression and infections of F. graminearum.

77 FR 65372 - Agency Information Collection Activities; Submission to the Office of Management and Budget for...

Science.gov (United States)

2012-10-26

... System. OMB Control Number: Pending. Type of Review: New collection, request for a new OMB Control Number... been issued the required two factor authentication tokens can access the FS SAS. The FS SAS allows...

A simulation study on the operating performance of a solar-air source heat pump water heater

International Nuclear Information System (INIS)

Xu Guoying; Zhang Xiaosong; Deng Shiming

2006-01-01

A simulation study on the operating performance of a new type of solar-air source heat pump water heater (SAS-HPWH) has been presented. The SAS-HPWH used a specially designed flat-plate heat collector/evaporator with spiral-finned tubes to obtain energy from both solar irradiation and ambient air for hot water heating. Using the meteorological data in Nanjing, China, the simulation results based on 150 L water heating capacity showed that such a SAS-HPWH can heat water up to 55 deg. C efficiently under various weather conditions all year around. In this simulation study, the influences of solar radiation, ambient temperature and compressor capacity on the performance of the SAS-HPWH were analyzed. In order to improve the overall operating performance, the use of a variable-capacity compressor has been proposed

Empirical Relationships Between Optical Properties and Equivalent Diameters of Fractal Soot Aggregates at 550 Nm Wavelength.

Science.gov (United States)

Pandey, Apoorva; Chakrabarty, Rajan K.; Liu, Li; Mishchenko, Michael I.

2015-01-01

Soot aggregates (SAs)-fractal clusters of small, spherical carbonaceous monomers-modulate the incoming visible solar radiation and contribute significantly to climate forcing. Experimentalists and climate modelers typically assume a spherical morphology for SAs when computing their optical properties, causing significant errors. Here, we calculate the optical properties of freshly-generated (fractal dimension Df = 1.8) and aged (Df = 2.6) SAs at 550 nm wavelength using the numericallyexact superposition T-Matrix method. These properties were expressed as functions of equivalent aerosol diameters as measured by contemporary aerosol instruments. This work improves upon previous efforts wherein SA optical properties were computed as a function of monomer number, rendering them unusable in practical applications. Future research will address the sensitivity of variation in refractive index, fractal prefactor, and monomer overlap of SAs on the reported empirical relationships.

Effects of restricted feeding and re-alimentation of dietary protein or ...

African Journals Online (AJOL)

2017-05-03

May 3, 2017 ... characteristics and meat eating quality parameters of sheep. ..... Data were analysed using the MIXED model procedure of SAS 9.3 (SAS Institute, Cary NC). All data ..... Nutrition Research Laboratory, Kuku, Khartoum North.

Summarizing evaluation of the results of in-pile experiments for the transient fission gas release under accidental conditions of fast breeders

International Nuclear Information System (INIS)

Fischer, E.A.; Vaeth, L.

1989-04-01

The transient fission gas behaviour and the fission gas induced fuel motion were studied in in-pile experiments in different countries, under conditions typical for hypothetical accidents. This report summarizes first the different experiment series and the main results. Then, a comparative evaluation is given, which provides a basis for the choice of the fission gas parameters in the accident code SAS3D

Chern–Simons–Antoniadis–Savvidy forms and standard supergravity

Energy Technology Data Exchange (ETDEWEB)

Izaurieta, F., E-mail: fizaurie@udec.cl; Salgado, P., E-mail: pasalgad@udec.cl; Salgado, S., E-mail: sesalgado@udec.cl

2017-04-10

In the context of the so called the Chern–Simons–Antoniadis–Savvidy (ChSAS) forms, we use the methods for FDA decomposition in 1-forms to construct a four-dimensional ChSAS supergravity action for the Maxwell superalgebra. On the another hand, we use the Extended Cartan Homotopy Formula to find a method that allows the separation of the ChSAS action into bulk and boundary contributions and permits the splitting of the bulk Lagrangian into pieces that reflect the particular subspace structure of the gauge algebra.

Body measurement characteristics of the West African Dwarf (WAD ...

African Journals Online (AJOL)

STORAGESEVER

2008-07-18

Jul 18, 2008 ... 1Faculty of Agricultural Sciences, Department of Animal Production and Health ... Two hundred and forty four (244) West African Dwarf (WAD) Goats ..... SAS Institute Inc. SAS Campus Drive. Carry. North. Carolina, U.S.A..

Ionic liquid-based microwave-assisted dispersive liquid-liquid microextraction and derivatization of sulfonamides in river water, honey, milk, and animal plasma

Energy Technology Data Exchange (ETDEWEB)

Xu Xu; Su Rui; Zhao Xin; Liu Zhuang; Zhang Yupu; Li Dan; Li Xueyuan; Zhang Hanqi [College of Chemistry, Jilin University, Changchun 130012 (China); Wang Ziming, E-mail: analchem@jlu.edu.cn [College of Chemistry, Jilin University, Changchun 130012 (China)

2011-11-30

Graphical abstract: The extraction and derivatization efficiency of SAs is dependent on type and volume of extraction solvent, type and volume of disperser, microwave power and irradiation time, volume of derivatization reagent, pH of sample solution as well as ionic strength. Highlights: Black-Right-Pointing-Pointer A new, rapid and sensitive method for determining sulfonamides (SAs) was proposed. Black-Right-Pointing-Pointer Derivatization, extraction and preconcentration of SAs were performed in one step. Black-Right-Pointing-Pointer IL-based MADLLME and derivatization were first applied for the determination of SAs. Black-Right-Pointing-Pointer Trace SAs in river water, honey, milk, and pig plasma were determined. - Abstract: The ionic liquid-based microwave-assisted dispersive liquid-liquid microextraction (IL-based MADLLME) and derivatization was applied for the pretreatment of six sulfonamides (SAs) prior to the determination by high-performance liquid chromatography (HPLC). By adding methanol (disperser), fluorescamine solution (derivatization reagent) and ionic liquid (extraction solvent) into sample, extraction, derivatization, and preconcentration were continuously performed. Several experimental parameters, such as the type and volume of extraction solvent, the type and volume of disperser, amount of derivatization reagent, microwave power, microwave irradiation time, pH of sample solution, and ionic strength were investigated and optimized. When the microwave power was 240 W, the analytes could be derivatized and extracted simultaneously within 90 s. The proposed method was applied to the analysis of river water, honey, milk, and pig plasma samples, and the recoveries of analytes obtained were in the range of 95.0-110.8, 95.4-106.3, 95.0-108.3, and 95.7-107.7, respectively. The relative standard deviations varied between 1.5% and 7.3% (n = 5). The results showed that the proposed method was a rapid, convenient and feasible method for the determination

Complex sleep apnea syndrome

Directory of Open Access Journals (Sweden)

Wang J

2013-07-01

Full Text Available Juan Wang,1,* Yan Wang,1,* Jing Feng,1,2 Bao-yuan Chen,1 Jie Cao1 1Respiratory Department of Tianjin Medical University General Hospital, Tianjin, People's Republic of China; 2Division of Pulmonary and Critical Care Medicine, Duke University Medical Center, Durham, NC, USA *The first two authors contributed equally to this work Abstract: Complex sleep apnea syndrome (CompSAS is a distinct form of sleep-disordered breathing characterized as central sleep apnea (CSA, and presents in obstructive sleep apnea (OSA patients during initial treatment with a continuous positive airway pressure (CPAP device. The mechanisms of why CompSAS occurs are not well understood, though we have a high loop gain theory that may help to explain it. It is still controversial regarding the prevalence and the clinical significance of CompSAS. Patients with CompSAS have clinical features similar to OSA, but they do exhibit breathing patterns like CSA. In most CompSAS cases, CSA events during initial CPAP titration are transient and they may disappear after continued CPAP use for 4–8 weeks or even longer. However, the poor initial experience of CompSAS patients with CPAP may not be avoided, and nonadherence with continued therapy may often result. Treatment options like adaptive servo-ventilation are available now that may rapidly resolve the disorder and relieve the symptoms of this disease with the potential of increasing early adherence to therapy. But these approaches are associated with more expensive and complicated devices. In this review, the definition, potential plausible mechanisms, clinical characteristics, and treatment approaches of CompSAS will be summarized. Keywords: complex sleep apnea syndrome, obstructive sleep apnea, central sleep apnea, apnea threshold, continuous positive airway pressure, adaptive servo-ventilation

The Reticulospinal Pathway Does Not Increase Its Contribution to the Strength of Contralesional Muscles in Stroke Survivors as Compared to Ipsilesional Side or Healthy Controls

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Sheng Li

2017-11-01

Full Text Available ObjectiveStartling acoustic stimulation (SAS, via activation of reticulospinal (RS pathways, has shown to increase muscle strength in healthy subjects. We hypothesized that, given RS hyperexcitability in stroke survivors, SAS could increase muscle strength in stroke survivors. The objective was to quantify the effect of SAS on maximal and sub-maximal voluntary elbow flexion on the contralesional (impaired side in stroke survivors as compared to ipsilesional (non-impaired side and healthy controls.DesignThirteen hemiparetic stroke survivors and 12 healthy subjects volunteered for this investigation. Acoustic stimulation was given at rest, during ballistic maximal and sustained sub-maximal isometric elbow contractions using low (80 dB and high intensity sound (105 dB. The effect of acoustic stimuli was evaluated from EMG and force recordings.ResultsPrevalence of acoustic startle reflex with shorter latency in the impaired biceps was greater as compared to the response in the non-impaired side of stroke subjects and in healthy subjects. Delivery of SAS resulted in earlier initiation of elbow flexion and greater peak torque in healthy subjects and in stroke subjects with spastic hemiplegia during maximal voluntary elbow flexion tasks. During sub-maximal elbow flexion tasks, SAS-induced force responses were slightly greater on the impaired side than the non-impaired side. However, no statistically significant difference was found in SAS-induced responses between impaired and non-impaired sides at maximal and sub-maximal elbow flexion tasks.ConclusionThe findings suggest RS hyperexcitability in stroke survivors with spastic hemiplegia. The results of similar SAS-induced responses between healthy and stroke subjects indicate that RS projections via acoustic stimulation are not likely to contribute to muscle strength for stroke survivors to a significant extent.

Ionic liquid-based microwave-assisted dispersive liquid–liquid microextraction and derivatization of sulfonamides in river water, honey, milk, and animal plasma

International Nuclear Information System (INIS)

Xu Xu; Su Rui; Zhao Xin; Liu Zhuang; Zhang Yupu; Li Dan; Li Xueyuan; Zhang Hanqi; Wang Ziming

2011-01-01

Graphical abstract: The extraction and derivatization efficiency of SAs is dependent on type and volume of extraction solvent, type and volume of disperser, microwave power and irradiation time, volume of derivatization reagent, pH of sample solution as well as ionic strength. Highlights: ► A new, rapid and sensitive method for determining sulfonamides (SAs) was proposed. ► Derivatization, extraction and preconcentration of SAs were performed in one step. ► IL-based MADLLME and derivatization were first applied for the determination of SAs. ► Trace SAs in river water, honey, milk, and pig plasma were determined. - Abstract: The ionic liquid-based microwave-assisted dispersive liquid–liquid microextraction (IL-based MADLLME) and derivatization was applied for the pretreatment of six sulfonamides (SAs) prior to the determination by high-performance liquid chromatography (HPLC). By adding methanol (disperser), fluorescamine solution (derivatization reagent) and ionic liquid (extraction solvent) into sample, extraction, derivatization, and preconcentration were continuously performed. Several experimental parameters, such as the type and volume of extraction solvent, the type and volume of disperser, amount of derivatization reagent, microwave power, microwave irradiation time, pH of sample solution, and ionic strength were investigated and optimized. When the microwave power was 240 W, the analytes could be derivatized and extracted simultaneously within 90 s. The proposed method was applied to the analysis of river water, honey, milk, and pig plasma samples, and the recoveries of analytes obtained were in the range of 95.0–110.8, 95.4–106.3, 95.0–108.3, and 95.7–107.7, respectively. The relative standard deviations varied between 1.5% and 7.3% (n = 5). The results showed that the proposed method was a rapid, convenient and feasible method for the determination of SAs in liquid samples.

Estimation of PWR spent fuel composition using SCALE and SWAT code systems

Energy Technology Data Exchange (ETDEWEB)

Shin, Hee Sung [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Kenya, Suyama; Hiroshi, Okuno [Japan Atomic Energy Research Institute, Tokyo (Japan)

2001-05-01

The isotopic composition calculations were performed for 26 spent fuel samples from Obrigheim PWR reactor and 55 spent fuel samples from 7 PWR reactors using SCALE4.4 SAS2H with 27, 44 and 238 group cross-section libraries and SWAT with 107 group cross-section library. For convenience, the ratio of the measured to calculated value was used as a parameter. The four kinds of the calculation results were compared with the measured data. For many important nuclides for burnup credit criticality safety evaluation, the four methods applied in this study showed good coincidence with measurements in general. More precise observations showed the following results. Less unity ratios were found for Pu-239 and -241 for selected 16 samples out of the 26 samples from Obrigheim reactor. Larger than unity ratios were found for Am-241 for both the 16 and 55 samples. Larger than unity ratios were found for Sm-149 for the 55 samples. In the case of 26 sample SWAT was generally accompanied by larger ratios than those of SAS2H with some exceptions. Based on the measured-to-calculated ratios for 71 samples of a combined set in which 16 selected samples and 55 samples were included, the correction factors that should be multiplied to the calculated isotopic compositions were generated for a conservative estimate of the neutron multiplication factor of a system containing PWR spent fuel, taking burnup credit into account.

Discussie over de metamorfose van Nederland

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I. de Haan

2006-01-01

Full Text Available N.C.F. van Sas, De metamorfose van Nederland. Van oude orde naar moderniteit, 1750-1900 Ido de Haan, N.C.F. van Sas, De metamorphose van Nederland The collection of articles, which N.C.F. van Sas wrote over the course of two decades, reflect a shift in the periodization of Dutch history; away from the beginning of the Kingdom of the United Netherlands in 1813, to what Van Sas describes  as the birth of modern politics in the Netherlands in the Patriot Revolt in the 1780s. His version of the modernization of Dutch society, a the meal so discussed in the socio-economic history of Jan Luiten van Zanden and Arthur van Riel, and the cultural approach of Joost Kloek and Wijnand Mijnhardt, stresses the political aspects of the metamorphosis in the Dutch Sattelzeit. Van Sas convincingly shows how this politicization of cultural ideals, and the revolutionary zeal with which this was practised, was not just an import from France but part and parcel of tendencies that were already present within Dutch society around 1800. Disappointingly, however, Van Sas refrains from giving a more general evaluation of the political reconstruction and innovation that took shape in the early nineteenth century, there by missing the opportunity to link these episodes to the discussion about the constitutional transition after 1848 and the renewed nationalism at the end of the nineteenth century.

RISA: Remote Interface for Science Analysis

Science.gov (United States)

Gabriel, C.; Ibarra, A.; de La Calle, I.; Salgado, J.; Osuna, P.; Tapiador, D.

2008-08-01

The Scientific Analysis System (SAS) is the package for interactive and pipeline data reduction of all XMM-Newton data. Freely distributed by ESA to run under many different operating systems, the SAS has been used by almost every one of the 1600 refereed scientific publications obtained so far from the mission. We are developing RISA, the Remote Interface for Science Analysis, which makes it possible to run SAS through fully configurable web service workflows, enabling observers to access and analyse data making use of all of the existing SAS functionalities, without any installation/download of software/data. The workflows run primarily but not exclusively on the ESAC Grid, which offers scalable processing resources, directly connected to the XMM-Newton Science Archive. A first project internal version of RISA was issued in May 2007, a public release is expected already within this year.

Ionic treatment for removal of sulfonamide and tetracycline classes of antibiotic

International Nuclear Information System (INIS)

Choi, Keun-Joo; Son, Hee-Jong; Kim, Seung-Hyun

2007-01-01

Self-decomposition and removal of antibiotics by ionic treatment was evaluated in this study. Seven sulfonamide classes (SA) and seven tetracycline classes (TA) of antibiotic were selected for this purpose. According to this study, self-decomposition of SAs and TAs was slow, and a considerable amount of antibiotics still remained after 15 days. Ionic treatment was effective for removal of SAs and TAs, but organic interference was observed. When dissolved organic (DOC) was present in raw water, the removal performance of antibiotics generally deteriorated due to competition with organics. SAs and TAs, which were present in ionic form at neutral pH, were removed through ion exchange. Their removal efficiencies were closely related to their chemical structure. Antibiotics with stronger electronegativity were easier to remove by ionic treatment. Equilibrium equations for removal of SAs and TAs by ionic treatment were also presented

Characterizing the Interaction between tartrazine and two serum albumins by a hybrid spectroscopic approach.

Science.gov (United States)

Pan, Xingren; Qin, Pengfei; Liu, Rutao; Wang, Jing

2011-06-22

Tartrazine is an artificial azo dye commonly used in food products. The present study evaluated the interaction of tartrazine with two serum albumins (SAs), human serum albumin (HSA) and bovine serum albumin (BSA), under physiological conditions by means of fluorescence, three-dimensional fluorescence, UV-vis absorption, and circular dichroism (CD) techniques. The fluorescence data showed that tartrazine could bind to the two SAs to form a complex. The binding process was a spontaneous molecular interaction procedure, in which van der Waals and hydrogen bond interactions played a major role. Additionally, as shown by the UV-vis absorption, three-dimensional fluorescence, and CD results, tartrazine could lead to conformational and some microenvironmental changes of both SAs, which may affect the physiological functions of SAs. The work provides important insight into the mechanism of toxicity of tartrazine in vivo.

Seismic attenuation system for the AEI 10 meter Prototype

International Nuclear Information System (INIS)

Wanner, A; Bergmann, G; Fricke, T; Lück, H; Mow-Lowry, C M; Strain, K A; Goßler, S; Danzmann, K; Bertolini, A

2012-01-01

Isolation from seismic motion is vital for vibration sensitive experiments. The seismic attenuation system (SAS) is a passive mechanical isolation system for optics suspensions. The low natural frequency of a SAS allows seismic isolation starting below 0.2 Hz. The desired isolation at frequencies above a few hertz is 70–80 dB in both horizontal and vertical degrees of freedom. An introduction to the SAS for the AEI 10 m Prototype, an overview of the mechanical design and a description of the major components are given. (paper)

Response of cowpea genotypes to Alectra vogelii parasitism in Kenya

African Journals Online (AJOL)

jakakah

2013-11-20

Nov 20, 2013 ... ... Eastern Kenya where it is attractive to farmers because of its high economic value .... model (GLM) procedure of SAS (version 8.0; SAS Institute, Cary, ..... ammonium nitrate, and light intensity on the growth and nodulation of.

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2014-12-11

Dec 11, 2014 ... selection intensity ranged from 0.59 % (hundred seed weight) to 78.1% (number of pods per plant). ... are the staple food, are often deficient in lysine (Geletu et al., 1996). .... GLM procedure of SAS software (SAS, 2004).

field control of peridomestic mosquitoes of medical importance

African Journals Online (AJOL)

2004-02-18

Feb 18, 2004 ... less potent than the aqueous extract under field conditions. The significance of ... Many plants in the family Phytollacaceae are known to be. 4°C until needed. ..... SAS User's guide: Statistics, version 5 SAS institute, to gravid ...

Banana nectar as a medium for testing pollen viability and ...

African Journals Online (AJOL)

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2007-05-16

May 16, 2007 ... The accession TMB2x 8075 - 7 showed no significant pollen germination in nectar and sucrose. Eleven genotypes (55%) showed significant increase in pollen ..... SAS (1999) SAS Institute Inc. Cary, USA. Sara CC, José OF, ...

7755 EFFECT OF NPK FERTILIZER ON FRUIT YIELD AND YIELD ...

African Journals Online (AJOL)

Win7Ent

2013-06-03

Jun 3, 2013 ... peasant farmers in Nigeria. With the increased ... did not significantly (p=0.05) increase the fruit yield nor the seed yield. Key words: NPK fertilizer, Fruit ..... SAS (Statistical Analysis System) Version 9.1. SAS Institute Inc., Cary, ...

A semi-analytical solution to accelerate spin-up of a coupled carbon and nitrogen land model to steady state

Directory of Open Access Journals (Sweden)

J. Y. Xia

2012-10-01

Full Text Available The spin-up of land models to steady state of coupled carbon–nitrogen processes is computationally so costly that it becomes a bottleneck issue for global analysis. In this study, we introduced a semi-analytical solution (SAS for the spin-up issue. SAS is fundamentally based on the analytic solution to a set of equations that describe carbon transfers within ecosystems over time. SAS is implemented by three steps: (1 having an initial spin-up with prior pool-size values until net primary productivity (NPP reaches stabilization, (2 calculating quasi-steady-state pool sizes by letting fluxes of the equations equal zero, and (3 having a final spin-up to meet the criterion of steady state. Step 2 is enabled by averaged time-varying variables over one period of repeated driving forcings. SAS was applied to both site-level and global scale spin-up of the Australian Community Atmosphere Biosphere Land Exchange (CABLE model. For the carbon-cycle-only simulations, SAS saved 95.7% and 92.4% of computational time for site-level and global spin-up, respectively, in comparison with the traditional method (a long-term iterative simulation to achieve the steady states of variables. For the carbon–nitrogen coupled simulations, SAS reduced computational cost by 84.5% and 86.6% for site-level and global spin-up, respectively. The estimated steady-state pool sizes represent the ecosystem carbon storage capacity, which was 12.1 kg C m⁻² with the coupled carbon–nitrogen global model, 14.6% lower than that with the carbon-only model. The nitrogen down-regulation in modeled carbon storage is partly due to the 4.6% decrease in carbon influx (i.e., net primary productivity and partly due to the 10.5% reduction in residence times. This steady-state analysis accelerated by the SAS method can facilitate comparative studies of structural differences in determining the ecosystem carbon storage capacity among biogeochemical models. Overall, the

Revealing the Universe to Our Community: NMSU's Society of Astronomy Students' Dedication to Public Outreach

Science.gov (United States)

Maldonado, Mercedes; Rees, S.; Medina, A.; Beasley, D.; Campos, A.; Chanover, N. J.; Uckert, K.; McKeever, J.

2014-01-01

The New Mexico State University (NMSU) Society of Astronomy Students (SAS) is an undergraduate organization centered on students’ passions for learning and sharing knowledge about the field of astronomy. The SAS strives to become one of the most active clubs on the NMSU campus by their involvement in both astronomy and non-astronomy related public outreach and community service events. NMSU is located in Las Cruces, NM, where Clyde Tombaugh made great contributions both to the field of astronomy and to our local community. He was able to spark the community's interest in astronomy and science in general; this is an aspect of his career that the SAS strives to emulate. To do this, the SAS participates in community outreach events with the goal of stimulating curiosity and providing opportunities for the public to observe and understand exciting phenomenon occurring in our universe. With help from the NMSU Astronomy Department, the SAS is able to volunteer alongside the Astronomy Graduate Student Organization (AGSO) at events for people of all ages. Working jointly with the AGSO allows us to be mentored by the very students who were in our shoes not long ago; they educate us about the wonders of the universe, just as we wish to educate the community. This provides an enlightening and enriching environment for both club and community members. The NMSU Astronomy Department hosts events for the entire community, such as observing nights held at Tombaugh Observatory — which SAS members attend and help advertise — where community members learn about and view objects in the night sky through telescopes. SAS members assist with field trips where local middle and elementary school students attend presentations and participate in astronomy-related activities on the NMSU campus. These hands-on activities are presented in an understandable way, and are meant to increase appreciation for all of the exciting subjects our universe has to offer. Other outreach events include

Engineering of quality requirements as perceived by near-shore development centers' architects in eastern Europe: the hole in the whole.

NARCIS (Netherlands)

Daneva, Maia; Marczak, Sabrina; Herrmann, Andrea; Torchiano, M.

2014-01-01

Context: To software architects (SAs), the quality requirements (QRs) to a software system are key to designing the software architecture. However, understanding SAs' roles in the QRs engineering activities only recently became a topic in empirical requirements engineering research and very little

Weighted Poisson analyses à la Goodman using SAS-GENMOD. [Paper presented at 15th SAS European Users Group International SEUGI Conference, Madrid, 12-16 May 1997].

NARCIS (Netherlands)

Vogelesang, A.W.

2010-01-01

In traffic safety analysis, weight factors are often applied, to correct for road length, traffic volume, numbers of kilometers driven, etc. Also, many data are subdivided into classes (road type: freeway, 80 km/hr, two lanes, rural area, etc); combining factors often leads to a

Association of Adolescent Dimensional Borderline Personality Pathology with Past and Current Nonsuicidal Self-Injury and Lifetime Suicidal Behavior: A Clinical Multicenter Study.

Science.gov (United States)

Kaess, Michael; Brunner, Romuald; Parzer, Peter; Edanackaparampil, Manju; Schmidt, Johannes; Kirisgil, Melek; Fischer, Gloria; Wewetzer, Christoph; Lehmkuhl, Gerd; Resch, Franz

Descriptive diagnoses of nonsuicidal self-injury (NSSI) and suicide attempts (SAs) may detract from underlying dimensional borderline personality pathology (D-BPP). This study aimed to investigate D-BPP in adolescent inpatients with NSSI and SAs. A consecutive sample of 359 adolescent inpatients was assessed for current and past NSSI and life-time SAs. D-BPP and current mental health problems were measured using the Dimensional Assessment of Personality Pathology and the Strengths and Difficulties Questionnaire, respectively. D-BPP was significantly associated with both current (p BPP or current mental health problems. A multivariate model did not show any additional influence of current mental health problems over and above D-BPP in predicting NSSI and SAs. It can be hypothesized that D-BPP underlies adolescent self-harm and may persist even after its termination, promoting a higher burden of mental health problems. © 2016 S. Karger AG, Basel.

In vitro cell transformation induced by synthetic amorphous silica nanoparticles.

Science.gov (United States)

Fontana, Caroline; Kirsch, Anaïs; Seidel, Carole; Marpeaux, Léa; Darne, Christian; Gaté, Laurent; Remy, Aurélie; Guichard, Yves

2017-11-01

Synthetic amorphous silica nanoparticles (SAS) are among the most widely produced and used nanomaterials, but little is known about their carcinogenic potential. This study aims to evaluate the ability of four different SAS, two precipitated, NM-200 and NM-201, and two pyrogenic, NM-202 and NM-203, to induce the transformation process. For this, we used the recently developed in vitro Bhas 42 cell transformation assay (CTA). The genome of the transgenic Bhas 42 cells contains several copies of the v-Ha-ras gene, making them particularly sensitive to tumor-promoter agents. The Bhas 42 CTA, which includes an initiation assay and a promotion assay, was validated in our laboratory using known soluble carcinogenic substances. Its suitability for particle-type substances was verified by using quartz Min-U-Sil 5 (Min-U-Sil) and diatomaceous earth (DE) microparticles. As expected given their known transforming properties, Min-U-Sil responded positively in the Bhas 42 CTA and DE responded negatively. Transformation assays were performed with SAS at concentrations ranging from 2μg/cm 2 to 80μg/cm 2 . Results showed that all SAS have the capacity to induce transformed foci, interestingly only in the promotion assay, suggesting a mode of action similar to tumor-promoter substances. NM-203 exhibited transforming activity at a lower concentration than the other SAS. In conclusion, this study showed for the first time the transforming potential of different SAS, which act as tumor-promoter substances in the Bhas 42 model of cell transformation. Copyright © 2017 Elsevier B.V. All rights reserved.

Surgical apgar score in patients undergoing lumbar fusion for degenerative spine diseases.

Science.gov (United States)

Ou, Chien-Yu; Hsu, Shih-Yuan; Huang, Jian-Hao; Huang, Yu-Hua

2017-01-01

Lumbar fusion is a procedure broadly performed for degenerative diseases of spines, but it is not without significant morbidities. Surgical Apgar Score (SAS), based on intraoperative blood loss, blood pressure, and heart rate, was developed for prognostic prediction in general and vascular operations. We aimed to examine whether the application of SAS in patients undergoing fusion procedures for degeneration of lumbar spines predicts in-hospital major complications. One hundred and ninety-nine patients that underwent lumbar fusion operation for spine degeneration were enrolled in this retrospective study. Based on whether major complications were present (N=16) or not (N=183), the patients were subdivided. We identified the intergroup differences in SAS and clinical parameters. The incidence of in-hospital major complications was 8%. The duration of hospital stay for the morbid patents was significantly prolonged (p=0.04). In the analysis of multivariable logistic regression, SAS was an independent predicting factor of the complications after lumbar fusion for degenerative spine diseases [p=0.001; odds ratio (95% confidence interval)=0.35 (0.19-0.64)]. Lower scores were accompanied with higher rates of major complications, and the area was 0.872 under the receiver operating characteristic curve. SAS is an independent predicting factor of major complications in patients after fusion surgery for degenerative diseases of lumbar spines, and provides good risk discrimination. Since the scoring system is relatively simple, objective, and practical, we suggest that SAS be included as an indicator in the guidance for level of care after lumbar fusion surgery. Copyright © 2016 Elsevier B.V. All rights reserved.

Remote sensing and geographic information system for appraisal of salt-affected soils in India.

Science.gov (United States)

Singh, Gurbachan; Bundela, D S; Sethi, Madhurama; Lal, Khajanchi; Kamra, S K

2010-01-01

Quantification of the nature, extent, and spatial distribution of salt-affected soils (SAS) for India and the world is essential for planning and implementing reclamation programs in a timely and cost-effective manner for sustained crop production. The national extent of SAS for India over the last four decades was assessed by conventional and remote sensing approaches using diverse methodologies and class definitions and ranged from 6.0 to 26.1 million hectares (Mha) and 1.2 to 10.1 Mha, respectively. In 1966, an area of 6 Mha under SAS was first reported using the former approach. Three national estimates, obtained using remote sensing, were reconciled using a geographic information system, resulting in an acceptable extent of 6.73 Mha. Moderately and severely salt-encrusted lands having large contiguous area have been correctly mapped, but slightly salt-encrusted land having smaller affected areas within croplands has not been accurately mapped. Recent satellite sensors (e.g., Resourcesat-1, Cartosat-2, IKONOS-II, and RISAT-2), along with improved image processing techniques integrated with terrain and other spatial data using a geographic information system, are enabling mapping at large scale. Significant variations in salt encrustation at the surface caused by soil moisture, waterlogging conditions, salt-tolerant crops, and dynamics of subsurface salts present constraints in appraisal, delineation, and mapping efforts. The article provides an overview of development, identification, characterization, and delineation of SAS, past and current national scenarios of SAS using conventional and remote sensing approaches, reconciliation of national estimates, issues of SAS mapping, and future scope.

Sickness absence among young employees: trends from 2002 to 2013.

Science.gov (United States)

Sumanen, Hilla; Pietiläinen, Olli; Lahti, Jouni; Lahelma, Eero; Rahkonen, Ossi

2015-01-01

Young adults entering employment are a key group in extending work careers, but there is a lack of research on trends in work ability among young employees. Prolonged sickness absence (SA) constitutes a risk for permanent work disability. We examined 12-year trends in SA spells among young female and male municipal employees. The data were obtained from the employers' registers in the City of Helsinki, Finland. The data included employees aged 18-24, 25-29, 30-34, and 35-54 from 2002 to 2013 (the average number for each year was 31,600). Self-certified (1-3 days) and medically certified intermediate (4-14 days) and long (15+ days) SAs were examined. Joinpoint regression models were used to identify major changes in SA trends. Younger employees had more short SAs but fewer long SAs than older employees. During the study period, SAs of almost any length first increased and later decreased among both genders, except for young men. The turning points for short SA were in 2007-2011 among younger and older employees. In intermediate and long SAs the respective turning points were in 2008-2009 and 2005-2009. Women had more SAs in all categories. Age is related to the length of absences. Given the relatively low chronic morbidity among younger employees, it is likely that reasons other than ill health account for increased SA. More evidence on factors behind the changing trends is needed in order to reduce SA and extend the working careers of young people.

Report on the establishment of the Southern African Student Affairs ...

African Journals Online (AJOL)

The formation of a South African federation was proposed in September 2007 by Ms. Naledi Pandor, then South ... SAFSAS hopes to strengthen collaboration between stakeholders within the higher education and ... SAS agenda, such as higher education transformation, models structures and strategies in. SAS, knowledge ...

Acceptance of NCPAP in a sample of patients admitted for geriatric rehabilitation

Directory of Open Access Journals (Sweden)

Frohnhofen H

2009-12-01

Full Text Available Abstract Objective Sleep apnea syndrome (SAS is common in older people. Nasal continuous airway pressure (NCPAP therapy is the treatment of choice for sleep apnea, but is not always accepted by patients. The rate of successful initiation of NCPAP is unknown in geriatric patients. Methods All patients admitted for geriatric rehabilitation were considered for sleep studies. Sleep apnea was assessed using an Edentrace (Nellcor, Hayward, CA multi-channel recording system. SAS was defined as an apnea-hypopnea-index (AHI of more than five events per hour plus excessive daytime sleepiness, or an AHI of more than fifteen events per hour regardless of reported sleepiness. Disability was assessed using the Barthel Index of Activities of Daily Living. Results Two hundred sixty nine of 322 consecutive patients (84% had adequate sleep studies and gave informed consent. SAS was found in 169 subjects (68%. There was no gender difference in the prevalence of SAS. Six subjects (4% accepted NCPAP therapy. Individuals who accepted NCPAP were younger and less disabled (p Conclusion NCPAP should not be withheld in the elderly. However, initiation of treatment for SAS remains to be a great challenge in those patients. Geriatric assessment procedures may help better manage older subjects with sleep apnea syndrome.

The effect of the 5e ınstructional model enriched with cooperative learning and animations on seventh-grade students’ academic achievement and scientific attitudes

Directory of Open Access Journals (Sweden)

İkramettin Daşdemir

2016-09-01

Full Text Available The aim of this research is to determine the effect of the different teaching methods, on seventh-grade students’ academic achievement and scientific attitudes. The research was carried out using quasi-experimental methods. The research sample consisted of 84 seventh grade students studying in three different classes. One of these classes an animation group, the second class was a cooperative group, the third was a control group. The data collection tools used were the Science Achievement Test (SAT and the Scientific Attitude Scale (SAS.When each group’s SAT and SAS pre-test ANOVA scores were compared, no significant differences were found between them. SAT post-test results showed a significant difference in favour of the animation group. In addition, the findings of the study revealed that the cooperative group’s mean post-test were not statistically significant. When SAS post-test scores of the animation and control groups were compared, there was a significant difference in favour of the animation group. When the SAS post-test scores of the cooperative and control groups were compared, there was a significant difference in favour of the cooperative group. When the SAS post-test scores of the cooperative and animation group were compared, there were no statistically significant differences in students’ attitudes.

The Effect of the 5E Instructional Model Enriched With Cooperative Learning and Animations on Seventh-Grade Students’ Academic Achievement and Scientific Attitudes

Directory of Open Access Journals (Sweden)

İkramettin DAŞDEMİR

2016-09-01

Full Text Available The aim of this research is to determine the effect of the different teaching methods, on seventh-grade students’ academic achievement and scientific attitudes. The research was carried out using quasi-experimental methods. The research sample consisted of 84 seventh grade students studying in three different classes. One of these classes an animation group, the second class was a cooperative group, the third was a control group. The data collection tools used were the Science Achievement Test (SAT and the Scientific Attitude Scale (SAS.When each group’s SAT and SAS pre-test ANOVA scores were compared, no significant differences were found between them. SAT post-test results showed a significant difference in favour of the animation group. In addition, the findings of the study revealed that the cooperative group’s mean post-test were not statistically significant. When SAS post-test scores of the animation and control groups were compared, there was a significant difference in favour of the animation group. When the SAS post-test scores of the cooperative and control groups were compared, there was a significant difference in favour of the cooperative group. When the SAS post-test scores of the cooperative and animation group were compared, there were no statistically significant differences in students’ attitudes.

Startle stimuli reduce the internal model control in discrete movements.

Science.gov (United States)

Wright, Zachary A; Rogers, Mark W; MacKinnon, Colum D; Patton, James L

2009-01-01

A well known and major component of movement control is the feedforward component, also known as the internal model. This model predicts and compensates for expected forces seen during a movement, based on recent experience, so that a well-learned task such as reaching to a target can be executed in a smooth straight manner. It has recently been shown that the state of preparation of planned movements can be tested using a startling acoustic stimulus (SAS). SAS, presented 500, 250 or 0 ms before the expected "go" cue resulted in the early release of the movement trajectory associated with the after-effects of the force field training (i.e. the internal model). In a typical motor adaptation experiment with a robot-applied force field, we tested if a SAS stimulus influences the size of after-effects that are typically seen. We found that in all subjects the after-effect magnitudes were significantly reduced when movements were released by SAS, although this effect was not further modulated by the timing of SAS. Reduced after-effects reveal at least partial existence of learned preparatory control, and identify startle effects that could influence performance in tasks such as piloting, teleoperation, and sports.

Immunohistochemical detection of receptor activator nuclear κB ligand and osteoprotegerin in odontogenic cysts and tumors.

Science.gov (United States)

de Matos, Felipe Rodrigues; de Moraes, Maiara; das Neves Silva, Emília Beatriz; Galvão, Hébel Cavalcanti; de Almeida Freitas, Roseana

2013-11-01

The aim of the present study was to compare the immunohistochemical detection of receptor activator nuclear κB ligand (RANKL) and osteoprotegerin (OPG) in radicular cysts (RCs), dentigerous cysts (DCs), solid ameloblastomas (SAs), and keratocystic odontogenic tumors (KOTs). A total of 20 RCs, 20 DCs, 20 KOTs, 14 dental follicles (DFs), and 18 SAs were evaluated by immunohistochemistry using anti-RANKL and anti-OPG antibodies. The analysis was quantitative, and the number of positive cells was counted in 10 microscopic high-power fields (400×). The DFs, KOTs, and SAs showed higher expression of RANKL than did the RCs and DCs in the epithelium (P < .05). The epithelial expression of OPG was higher in the DFs, KOTs, RCs, and DCs than in the SAs (P < .05). The ratio of OPG less than RANKL was more frequent in SAs and OPG greater than RANKL in DCs (P < .05). Our results have shown differences in RANKL and OPG detection in the odontogenic cysts and tumors studied. The higher RANKL and lower OPG detection in SA could play a role in bone resorption, compatible with the tumor's biologic behavior. Copyright © 2013 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Treating kleptomania: cross-cultural adaptation of the Kleptomania Symptom Assessment Scale and assessment of an outpatient program.

Science.gov (United States)

Christianini, Aparecida Rangon; Conti, Maria Aparecida; Hearst, Norman; Cordás, Táki Athanássios; de Abreu, Cristiano Nabuco; Tavares, Hermano

2015-01-01

Kleptomania is characterized by repetitive stealing and has severe consequences for patients. Stigma, a lack of standardized therapy and a limited number of assessment tools hinder advances in treatment. This study provides preliminary data on the Portuguese-language version of the Kleptomania Symptom Assessment Scale (P-K-SAS) and preliminary data on an outpatient program. Experts in the field analyzed an initial P-K-SAS version, produced through translation/back-translation, in order to arrive at a final version. Eight patients currently on cognitive-behavioral therapy (CBT) and 10 patients under maintenance CBT were initially assessed, then re-assessed 6months later. The mean P-K-SAS score was higher among patients initiating CBT than among those under maintenance CBT (21.1±8.0 vs. 11.3±7.5; Mann-Whitney U=15.0, P=.024). The final version of the P-K-SAS presented excellent reliability (Cronbach's alpha=0.980; inter-item correlation, 0.638-0.907). The P-K-SAS presented solid psychometrics and seems ready for use in assessing the effectiveness of treatments for kleptomania. The findings suggest that kleptomania patients need follow-up treatment that goes beyond the traditional 12-session structure. Copyright © 2014 Elsevier Inc. All rights reserved.

The smartphone addiction scale: development and validation of a short version for adolescents.

Science.gov (United States)

Kwon, Min; Kim, Dai-Jin; Cho, Hyun; Yang, Soo

2013-01-01

This study was designed to investigate the revised and short version of the smartphone addiction scale and the proof of its validity in adolescents. In addition, it suggested cutting off the values by gender in order to determine smartphone addiction and elaborate the characteristics of smartphone usage in adolescents. A set of questionnaires were provided to a total of 540 selected participants from April to May of 2013. The participants consisted of 343 boys and 197 girls, and their average age was 14.5 years old. The content validity was performed on a selection of shortened items, while an internal-consistency test was conducted for the verification of its reliability. The concurrent validity was confirmed using SAS, SAPS and KS-scale. Receiver operating characteristics analysis was conducted to suggest cut-off. The 10 final questions were selected using content validity. The internal consistency and concurrent validity of SAS were verified with a Cronbach's alpha of 0.911. The SAS-SV was significantly correlated with the SAS, SAPS and KS-scale. The SAS-SV scores of gender (psmartphone addiction (psmartphone addiction. The smartphone addiction scale short version, which was developed and validated in this study, could be used efficiently for the evaluation of smartphone addiction in community and research areas.

Prophylactic Neuroprotection of Total Glucosides of Paeoniae Radix Alba against Semen Strychni-Induced Neurotoxicity in Rats: Suppressing Oxidative Stress and Reducing the Absorption of Toxic Components.

Science.gov (United States)

Li, Shujuan; Chu, Yanjie; Zhang, Ruowen; Sun, Linjia; Chen, Xiaohui

2018-04-20

Strychnos alkaloids (SAs) are the main toxic constituents in Semen Strychni, a traditional Chinese medicine, which is known for its fatal neurotoxicity. Hence, the present study was carried out to evaluate the neurotoxicity induced by SAs and the pre-protective effects of the total glucosides of Paeoniae Radix Alba (TGP). An SA brain damage model was firstly established. The neurotoxicity induced by SAs and the pre-protective effects of TGP were confirmed by physical and behavioral testing, biochemical assay, and histological examination. Then, a liquid chromatography-tandem mass spectrometry method was developed and validated to investigate the time-course change and distribution of strychnine and brucine (two main SAs) in the brain after oral SA administration with or without TGP pretreatment. Biochemical analysis results indicated that TGP could ameliorate the oxidative stress status caused by SAs. Time-course change and distribution studies demonstrated that strychnine and brucine were rapidly absorbed into the brain, peaked early at 0.5 h, and were mainly located in the hippocampus and cerebellum. TGP showed a pre-protective effect against neurotoxicity by reducing the absorption of toxic alkaloids into the brain. These findings could provide beneficial information in facilitating future studies of Semen Strychni neurotoxicity and developing herbal medicines to alleviate neurotoxicity in the clinic.

Prophylactic Neuroprotection of Total Glucosides of Paeoniae Radix Alba against Semen Strychni-Induced Neurotoxicity in Rats: Suppressing Oxidative Stress and Reducing the Absorption of Toxic Components

Directory of Open Access Journals (Sweden)

Shujuan Li

2018-04-01

Full Text Available Strychnos alkaloids (SAs are the main toxic constituents in Semen Strychni, a traditional Chinese medicine, which is known for its fatal neurotoxicity. Hence, the present study was carried out to evaluate the neurotoxicity induced by SAs and the pre-protective effects of the total glucosides of Paeoniae Radix Alba (TGP. An SA brain damage model was firstly established. The neurotoxicity induced by SAs and the pre-protective effects of TGP were confirmed by physical and behavioral testing, biochemical assay, and histological examination. Then, a liquid chromatography-tandem mass spectrometry method was developed and validated to investigate the time-course change and distribution of strychnine and brucine (two main SAs in the brain after oral SA administration with or without TGP pretreatment. Biochemical analysis results indicated that TGP could ameliorate the oxidative stress status caused by SAs. Time-course change and distribution studies demonstrated that strychnine and brucine were rapidly absorbed into the brain, peaked early at 0.5 h, and were mainly located in the hippocampus and cerebellum. TGP showed a pre-protective effect against neurotoxicity by reducing the absorption of toxic alkaloids into the brain. These findings could provide beneficial information in facilitating future studies of Semen Strychni neurotoxicity and developing herbal medicines to alleviate neurotoxicity in the clinic.

Validación de la Sexual Assertiveness Scale en mujeres mexicanas

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Reyna Torres-Obregon

2017-01-01

Full Text Available La asertividad sexual constituye una dimensión fundamental de la sexualidad humana por su relación con distintos indicadores de la salud sexual. Es la capacidad de las personas para iniciar la actividad sexual, rechazar la actividad sexual no deseada y emplear métodos anticonceptivos y así desarrollar comportamientos saludables. Esta se mide a través de la Sexual Assertiveness Scale (SAS. Hasta la fecha, la SAS no se ha validado en población mexicana, por lo que se considera importante examinar sus propiedades psicométricas en esta población. Por lo tanto, este estudio tuvo como objetivo validar la SAS en una muestra de 202 mujeres mexicanas. Mediante un análisis factorial confirmatorio, se confirmó la estructura trifactorial del SAS: inicio, rechazo y embarazo-enfermedades de transmisión sexual (CFI = .953; TLI = .927. Asimismo, se obtuvo una confiabilidad adecuada en las tres subescalas y, de forma global (ω = .85, sus puntuaciones correlacionaron significativamente en la dirección esperada con autoestima sexual y depresión rasgo. Se concluye que la SAS presenta buenas propiedades psicométricas en población femenina mexicana.

Uncertainty in unprotected loss-of-heat-sink, loss-of-flow, and transient-overpower accidents.

Energy Technology Data Exchange (ETDEWEB)

Morris, E. E.; Nuclear Engineering Division

2007-10-08

The sensitivities of various output parameters to selected input parameters in unprotected combined loss of heat-sink and loss-of-flow (ULOHS), loss-of-flow (ULOF), and transient-overpower (UTOP) accidents are explored in this report. This line of investigation was suggested by R. A. Wigeland. For an initial examination of potential sensitivities, the MATWS computer program has been compiled as part of a dynamic link library (DLL) so that uncertain input parameters can be sampled from their probability distributions using the GoldSim simulation software. The MATWS program combines the point-kinetics module from the SAS4A/SASSYS computer code with a simplified representation of the reactor heat removal system. Coupling with the GoldSim software by means of a DLL not only provides a convenient mechanism for sampling the stochastic input parameters but also allows the use of various tools that are available in GoldSim for analyzing the dependence of various MATWS outputs on these parameters. Should a decision be made to continue this investigation, the techniques used to couple MATWS and GoldSim could also be applied to couple the SAS4A/SASSYS computer code with GoldSim. The work described here illustrates the type of results that can be obtained from the stochastic analysis.

Uncertainty in unprotected loss-of-heat-sink, loss-of-flow, and transient-overpower accidents

International Nuclear Information System (INIS)

Morris, E.E.

2007-01-01

The sensitivities of various output parameters to selected input parameters in unprotected combined loss of heat-sink and loss-of-flow (ULOHS), loss-of-flow (ULOF), and transient-overpower (UTOP) accidents are explored in this report. This line of investigation was suggested by R. A. Wigeland. For an initial examination of potential sensitivities, the MATWS computer program has been compiled as part of a dynamic link library (DLL) so that uncertain input parameters can be sampled from their probability distributions using the GoldSim simulation software. The MATWS program combines the point-kinetics module from the SAS4A/SASSYS computer code with a simplified representation of the reactor heat removal system. Coupling with the GoldSim software by means of a DLL not only provides a convenient mechanism for sampling the stochastic input parameters but also allows the use of various tools that are available in GoldSim for analyzing the dependence of various MATWS outputs on these parameters. Should a decision be made to continue this investigation, the techniques used to couple MATWS and GoldSim could also be applied to couple the SAS4A/SASSYS computer code with GoldSim. The work described here illustrates the type of results that can be obtained from the stochastic analysis

Dear Author,

African Journals Online (AJOL)

pepsi

2013-05-22

May 22, 2013 ... vitro micropropagation technique is widely used in orna- mental crops. ... MATERIALS AND METHODS. Plant material and cultural ... NAA and TDZ in each experiment were considered as treatments; each treatment was ... analysis of variance (ANOVA) using the SAS software (SAS 1990). If treatments were ...

Evaluation of a novel cryoballoon swipe ablation system in bench, porcine, and human esophagus models

NARCIS (Netherlands)

Louie, B. E.; Hofstetter, W.; Triadafilopoulos, G.; Weusten, B. L.

2018-01-01

Current ablation devices for dysplastic Barrett's esophagus are effective but have significant limitations. This pilot study aims to evaluate the safety, feasibility, and dose response of a novel cryoballoon swipe ablation system (CbSAS) in three experimental in vitro and in vivo models. CbSAS is a

Oral two-generation reproduction toxicity study with NM-200 synthetic amorphous silica in Wistar rats

NARCIS (Netherlands)

Wolterbeek, A.; Oosterwijk, T.; Schneider, S.; Landsiedel, R.; Groot, D. de; Ee, R. van; Wouters, M.; Sandt, H. van de

2015-01-01

Synthetic amorphous silica (SAS) like NM-200 is used in a wide variety of technological applications and consumer products. Although SAS has been widely investigated the available reproductive toxicity studies are old and do not cover all requirements of current OECD Guidelines. As part of a

Cresco sai lahti võlast SASile ja osalusest Estonian Airis / Rivo Sarapik, Alyona Stadnik

Index Scriptorium Estoniae

Sarapik, Rivo, 1981-

2010-01-01

Majandus- ja kommunikatsiooniminister Juhan Parts ning SAS-i asepresident Benny Zakrisson kirjutasid alla Estonian Airi ostu-müügitehingule. Investeerimispank Cresco, millele kuulus 17% Estonian Airist, jääb välja Estonian Airi omanikeringist ning SAS-i nõue Crescole tühistatakse

The STAR Grants Contribution to the SOAS Campaign

Science.gov (United States)

The Southern Oxidant and Aerosol Study (SOAS) is a community-led field campaign that was part of the Southeast Atmosphere Study (SAS). As one of the largest field studies in decades to characterize air quality in the Southeastern United States, SAS is a collaborative project invo...

Videoradiography of patients with habitual snoring and/or sleep apnea. Technical description and presentation of videoradiographic results during sleep concerning occurrence of apnea, type of apnea, and site of obstruction

International Nuclear Information System (INIS)

Hillarp, B.; Nylander, G.; Rosen, I.; Wickstroem, O.

1995-01-01

The videoradiographic examination described was designed for habitual snorers and sleep apnea syndrome (SAS) patients and was performed during wakefulness and sleep. During wakefulness the purpose was to reveal any dysfunction in deglutiton and speech as well as morphologic abnormalities. The purpose during sleep, which usually was induced by low-dose midazolam intravenously, was to reveal the site and form of obstruction in obstructive sleep apnea patients and the site of snoring in habitual snorers. The preoperative results of 104 patients are presented. In 57 patients who had apneas, the occurrence and type of apnea could be determined. A continuous recording over some minutes gave a rough estimate of the degree of SAS and mean duration of apnea. Although much information on SAS can be obtained by this method, it cannot replace polygraphic sleep recording in the investigation of habitual snorers and SAS patients. However, these 2 methods are complementary and can be performed simultaneously as polygraphic videoradiography. (orig.)

A Practical Guide To Solar Array Simulation And PCDU Test

Science.gov (United States)

Schmitz, Noah; Carroll, Greg; Clegg, Russell

2011-10-01

Solar arrays consisting of multiple photovoltaic segments provide power to satellites and charge internal batteries for use during eclipse. Solar arrays have unique I-V characteristics and output power which vary with environmental and operational conditions such as temperature, irradiance, spin, and eclipse. Therefore, specialty power solutions are needed to properly test the satellite on the ground, especially the Power Control and Distribution Unit (PCDU) and the Array Power Regulator (APR.) This paper explores some practical and theoretical considerations that should be taken into account when choosing a commercial, off-the-shelf solar array simulator (SAS) for verification of the satellite PCDU. An SAS is a unique power supply with I-V output characteristics that emulate the solar arrays used to power a satellite. It is important to think about the strengths and the limitations of this emulation capability, how closely the SAS approximates a real solar panel, and how best to design a system using SAS as components.

Analysis of depression and anxiety state and changes of regional cerebral blood flow in patients with Graves' disease

International Nuclear Information System (INIS)

Yu Jiangyuan; Li Yaming; Yin Yafu; Li Xuena; Han Chunqi; Li Deshun; Liu Hao; Li Na; Liang Chenrong; Sun Zhenqiu

2006-01-01

Objective: To explore the incidence of depression and anxiety state and the changes of regional cerebral blood flow (rCBF) in patients with Graves' disease (GD). Methods: Twenty-one GD patients underwent rCBF SPECT imaging, and their mental state was evaluated by Zung self-rating depression scale (SDS) and Zung self-rating anxiety scale (SAS) respectively. Results: Total scores obtained from SDS and SAS were both significantly greater in the GD group than that in the control group (t SDS =7.26, t SAS =5.35, P 3 , FT 4 and TSH levels. In SPECT imaging, GD group had decreased uptake of radioactivity in frontal lobs, temporal lobs, basal ganglia and thalamus mainly. There was also no significant correlation between the decrease of rCBF and SDS or SAS scores. Conclusions: The psychiatric symptoms in GD group are more significant than normal controls, rCBF of GD group decreases mainly in bilateral frontal lobes, temporal lobes, basal ganglia and thalamus. (authors)

Enhancing sibling relationships to prevent adolescent problem behaviors: theory, design and feasibility of Siblings Are Special.

Science.gov (United States)

Feinberg, Mark E; Sakuma, Kari-Lyn; Hostetler, Michelle; McHale, Susan M

2013-02-01

Siblings play a significant but neglected role in family socialization dynamics, and focusing on the sibling relationship is a non-stigmatizing point of entry into the family for prevention programming. Siblings are Special (SAS) was designed as a universal program that targets both sibling relationship and parenting mediating processes in middle childhood to prevent behavior problems in adolescence. We describe the theoretical framework underlying SAS, the SAS curriculum, and the feasibility of the program based on a study of 128 middle-childhood aged sibling dyads. Data on the quality of program implementation, program fidelity, siblings' engagement, and ratings of impact indicated the SAS program was acceptable to families and schools, that the curriculum could be implemented with high fidelity, that siblings and parents participated at high levels and were highly engaged, and that, from the perspective of group leaders, school administrators and parents, the program had a positive impact on the siblings. Copyright © 2012 Elsevier Ltd. All rights reserved.

Near-infrared transillumination back scattering sounding--new method to assess brain microcirculation in patients with chronic carotid artery stenosis.

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Andrzej F Frydrychowski

Full Text Available PURPOSE: The purpose of the study was to assess the responses of pial artery pulsation (cc-TQ and subarachnoid width (sas-TQ to acetazolamide challenge in patients with chronic carotid artery stenosis and relate these responses to changes in peak systolic velocity (PSV, cerebral blood flow (CBF, cerebral blood volume (CBV, mean transit time (MTT and time to peak response (TTP. METHODS: Fifteen patients with carotid artery stenosis ≥ 90% on the ipsilateral side and <50% on the contralateral side were enrolled into the study. PSV was assessed using colour-coded duplex sonography, CBF, CBV, MTT and TTP with perfusion computed tomography, cc-TQ and sas-TQ with near-infrared transillumination/backscattering sounding (NIR-T/BSS. RESULTS: Based on the ipsilateral/contralateral cc-TQ ratio after acetazolamide challenge two groups of patients were distinguished: the first group with a ratio ≥ 1 and the second with a ratio <1. In the second group increases in CBF and CBV after the acetazolamide test were significantly higher in both hemispheres (ipsilateral: +33.0% ± 8.1% vs. +15.3% ± 4.4% and +26.3% ± 6.6% vs. +14.3% ± 5.1%; contralateral: +26.8% ± 7.0% vs. +17.6% ± 5.6% and +20.0% ± 7.3% vs. +10.0% ± 3.7%, respectively, cc-TQ was significantly higher only on the ipsilateral side (+37.3% ± 9.3% vs. +26.6% ± 8.6% and the decrease in sas-TQ was less pronounced on the ipsilateral side (-0.7% ± 1.5% vs. -10.2% ± 1.5%, in comparison with the first group. The changes in sas-TQ following the acetazolamide test were consistent with the changes in TTP. CONCLUSIONS: The ipsilateral/contralateral cc-TQ ratio following acetazolamide challenge may be used to distinguish patient groups characterized by different haemodynamic parameters. Further research on a larger group of patients is warranted.

A universal next generation sequencing protocol to generate non-infectious barcoded cDNA libraries from high containment RNA viruses

Science.gov (United States)

Several biosafety level (BSL)-3/4 pathogens are high consequence, single-stranded RNA viruses and their genomes, when introduced into permissive cells, are infectious. Moreover many of these viruses are Select Agents (SAs), and their genomes are also considered SAs. For this reason cDNAs and/or th...

Association of LEI0258 microsatellite alleles with antibody response ...

African Journals Online (AJOL)

SERVER

2008-03-18

Mar 18, 2008 ... (MHC) B region on chicken Micro-chromosome 16 has been demonstrated by many workers to be ... promising DNA markers in characterizing MHC B genes. Identifying marker alleles (bands) ..... SAS/STAT Users' Guide,. Release 6.12 Edition, SAS Institute Inc, Cary, North Carolina. USA. Taylor RL (2004).

SAS2 : Guide sur la recherche collaborative et l'engagement social ...

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1 janv. 2008 ... Innovation. Solutions. Carrières · Communiquez avec nous · Plan du site. Abonnez-vous à notre bulletin pour recevoir les nouvelles du CRDI chaque mois. Abonnez-vous · Droits d'auteur · Éthique de la recherche · Politique de libre accès · Politique de confidentialité · Transparence · Utilisation du site Web.

'N perd van 'n ander kleur sas somerset (1942-1986) | Wessels ...

African Journals Online (AJOL)

Naas die bekende vlootvaartuie soos byvoorbeeld duikbote, vliegdekskepe en missieldraende aanvalsvaartuie, is daar in die meeste vlote ter werêld ander vaartuigtipes wat soms 'n groot deel van hul leeftyd hawegebonde is, maar nogtans waardevolle diens ten behoewe van ander skepe of ter beskerming van hawens ...

Design and analysis of experiments classical and regression approaches with SAS

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Onyiah, Leonard C

2008-01-01

Introductory Statistical Inference and Regression Analysis Elementary Statistical Inference Regression Analysis Experiments, the Completely Randomized Design (CRD)-Classical and Regression Approaches Experiments Experiments to Compare Treatments Some Basic Ideas Requirements of a Good Experiment One-Way Experimental Layout or the CRD: Design and Analysis Analysis of Experimental Data (Fixed Effects Model) Expected Values for the Sums of Squares The Analysis of Variance (ANOVA) Table Follow-Up Analysis to Check fo

Development of the JFT-2M data analysis software system on the mainframe computer

International Nuclear Information System (INIS)

Matsuda, Toshiaki; Amagai, Akira; Suda, Shuji; Maemura, Katsumi; Hata, Ken-ichiro.

1990-11-01

We developed software system on the FACOM mainframe computer to analyze JFT-2M experimental data archived by JFT-2M data acquisition system. Then we can reduce and distribute the CPU load of the data acquisition system. And we can analyze JFT-2M experimental data by using complicated computational code with raw data, such as equilibrium calculation and transport analysis, and useful software package like SAS statistic package on the mainframe. (author)

[The long road for psychiatric care in prisons].

Science.gov (United States)

Laurencin, Gérard

2016-01-01

From the 19th century to the present day, the history of psychiatry in prisons has evolved considerably. In parallel with successive laws, codes and articles, psychiatry has gained in structure. From the "medical prison", mental health consultations in every detention centre, the regional medico-psychological services, to today's specially equipped hospital units (UHSA), prisoners receive both preventive care as well as curative treatment. Copyright © 2016. Published by Elsevier Masson SAS.

Neural processes mediating the preparation and release of focal motor output are suppressed or absent during imagined movement

Science.gov (United States)

Eagles, Jeremy S.; Carlsen, Anthony N.

2016-01-01

Movements that are executed or imagined activate a similar subset of cortical regions, but the extent to which this activity represents functionally equivalent neural processes is unclear. During preparation for an executed movement, presentation of a startling acoustic stimulus (SAS) evokes a premature release of the planned movement with the spatial and temporal features of the tasks essentially intact. If imagined movement incorporates the same preparatory processes as executed movement, then a SAS should release the planned movement during preparation. This hypothesis was tested using an instructed-delay cueing paradigm during which subjects were required to rapidly release a handheld weight while maintaining the posture of the arm or to perform first-person imagery of the same task while holding the weight. In a subset of trials, a SAS was presented at 1500, 500, or 200 ms prior to the release cue. Task-appropriate preparation during executed and imagined movements was confirmed by electroencephalographic recording of a contingent negative variation waveform. During preparation for executed movement, a SAS often resulted in premature release of the weight with the probability of release progressively increasing from 24 % at −1500 ms to 80 % at −200 ms. In contrast, the SAS rarely (movement. However, the SAS frequently evoked the planned postural response (suppression of bicep brachii muscle activity) irrespective of the task or timing of stimulation (even during periods of postural hold without preparation). These findings provide evidence that neural processes mediating the preparation and release of the focal motor task (release of the weight) are markedly attenuated or absent during imagined movement and that postural and focal components of the task are prepared independently. PMID:25744055

Acute hypoxia diminishes the relationship between blood pressure and subarachnoid space width oscillations at the human cardiac frequency.

Directory of Open Access Journals (Sweden)

Magdalena Wszedybyl-Winklewska

Full Text Available Acute hypoxia exerts strong effects on the cardiovascular system. Heart-generated pulsatile cerebrospinal fluid motion is recognised as a key factor ensuring brain homeostasis. We aimed to assess changes in heart-generated coupling between blood pressure (BP and subarachnoid space width (SAS oscillations during hypoxic exposure.Twenty participants were subjected to a controlled decrease in oxygen saturation (SaO2 = 80% for five minutes. BP and heart rate (HR were measured using continuous finger-pulse photoplethysmography, oxyhaemoglobin saturation with an ear-clip sensor, end-tidal CO2 with a gas analyser, and cerebral blood flow velocity (CBFV, pulsatility and resistive indices with Doppler ultrasound. Changes in SAS were recorded with a recently-developed method called near-infrared transillumination/backscattering sounding. Wavelet transform analysis was used to assess the relationship between BP and SAS oscillations.Gradual increases in systolic, diastolic BP and HR were observed immediately after the initiation of hypoxic challenge (at fifth minute +20.1%, +10.2%, +16.5% vs. baseline, respectively; all P<0.01, whereas SAS remained intact (P = NS. Concurrently, the CBFV was stable throughout the procedure, with the only increase observed in the last two minutes of deoxygenation (at the fifth minute +6.8% vs. baseline, P<0.05. The cardiac contribution to the relationship between BP and SAS oscillations diminished immediately after exposure to hypoxia (at the fifth minute, right hemisphere -27.7% and left hemisphere -26.3% vs. baseline; both P<0.05. Wavelet phase coherence did not change throughout the experiment (P = NS.Cerebral haemodynamics seem to be relatively stable during short exposure to normobaric hypoxia. Hypoxia attenuates heart-generated BP SAS coupling.

MR imaging of brain surface structures

International Nuclear Information System (INIS)

Katada, Kazuhiro; Anno, Hirofumi; Takesita, Gen; Koga, Sukehiko; Kanno, Tetuo; Sakakibara, Tatuo; Yamada, Kazuhiro; Suzuki, Hirokazu; Saito, Sigeki.

1989-01-01

An imaging technique that permits direct and non-invasive visualization of brain surface structures was proposed. This technique (Surface anatomy scanning, SAS) consists of long TE-long TR spin echo sequence, thick slice and surface coil. Initial clinical trials in 31 patients with various cerebral pathology showed excellent visualization of sulci, gyri and major cortical veins on the lateral surface of the brain together with cortical and subcortical lesions. Our preliminary results indicate that the SAS is an effective method for the diagnosis and localization of cortical and subcortical pathology, and the possible application of SAS to the surgical and the radiation therapy planning is sugessted. (author)

Black phosphorus saturable absorber for Q-switched Er:YAG laser at 1645 nm

Science.gov (United States)

Guo, Lei; Li, Tao; Zhang, Shuaiyi; Wang, Mingjian; Yang, Kejian; Fan, Mingqi; Zhao, Shengzhi; Li, Ming

2018-03-01

A Q-switched Er:YAG solid-state laser at 1645 nm based on black phosphorus (BP) saturable absorbers (SAs) was demonstrated firstly to our knowledge. The BP-SA was fabricated by drop-casting BP nanoplatelets dispersion on a YAG substrate and corresponding saturable absorption properties were characterized at 1.6 μm. By employing as-prepared BP-SAs, stable Q-switched laser operations were achieved with a pulse width of 2.8 μs and a repetition rate of 34 kHz, corresponding to the average output power of 0.33 W. The results verify that BP-SAs have great potential for pulsed 1.6 μm lasers.

AICPA standard aids in detecting risk factors for fraud. American Institute of Certified Public Accountants.

Science.gov (United States)

Reinstein, A; Dery, R J

1999-10-01

The American Institute of Certified Public Accountants' Statement on Auditing Standards (SAS) No. 82, Consideration of Fraud in a Financial Statement Audit, requires independent auditors to obtain reasonable assurance that financial statements are free of material mis-statements caused by error or fraud. SAS No. 82 provides guidance for independent auditors to use to help detect and document risk factors related to potential fraud. But while SAS No. 82 suggests how auditors should assess the potential for fraud, it does not expand their detection responsibility. Accordingly, financial managers should discuss thoroughly with auditors the scope and focus of an audit as a means to further their compliance efforts.

Repeated subretinal surgery and removal of subretinal decalin is well tolerated

DEFF Research Database (Denmark)

Sørensen, Nina Buus; Klemp, Kristian; Kjær, Troels Wesenberg

2017-01-01

flexible tube. Two weeks after removal, a control mfERG was recorded, the pigs were enucleated and sacrificed and eyes were examined histologically. All statistics were carried out with a paired t-test in SAS Enterprise Guide 7.1® (SAS Institute Inc., Cary, NC, USA). RESULTS: There was no significant...

Sustaining Competitiveness: Moving Towards Upstream Manufacturing in Specialized-Market-Based Clusters in the Chinese Toy Industry

Directory of Open Access Journals (Sweden)

Huasheng Zhu

2016-02-01

Full Text Available Western industrial cluster literature pays little attention to specialized markets (SMs and the geographical agglomeration of distributors or sale agencies (SAs. This paper takes Linyin, Shandong, a famous commodity city in Northeastern China, as an example, to discuss the determinants that make SAs in SMs of the toy industry move towards upstream manufacturing. A structured questionnaire survey and subsequent interviews were carried out during 2011 and 2012 to collect data, and a Binary Logistic Regression Model was used to process the data. This paper looks from the perspective of global production networks theory, establishes an analytical framework that combines individual motivations of intra-firm coordination, local inter-firm relationships and dynamic cross-regional level relationships. The findings indicate that the expansion of SAs towards manufacturing allows them to sustain competitiveness under changing circumstances. The local inter-firm relationships within SM-based clusters not only makes it easy to obtain material and human resources with lower manufacturing costs, but also facilitates the access to production knowledge and technologies for an expansion of production scale. Cross-regional relationships with suppliers provide an informal channel for SAs to obtain skills, which is fundamental for an expansion into manufacturing. In addition, it is a preference for strengthening competitiveness rather than the simple pursuit of economic profit that encourages SAs to invest in manufacturing.

Agreement between hospital discharge diagnosis codes and medical records to identify metastatic colorectal cancer and associated comorbidities in elderly patients.

Science.gov (United States)

Gouverneur, A; Dolatkhani, D; Rouyer, M; Grelaud, A; Francis, F; Gilleron, V; Fourrier-Réglat, A; Noize, P

2017-08-01

Quality of coding to identify cancers and comorbidities through the French hospital diagnosis database (Programme de médicalisation des systèmes d'information, PMSI) has been little investigated. Agreement between medical records and PMSI database was evaluated regarding metastatic colorectal cancer (mCRC) and comorbidities. From 01/01/2013 to 06/30/2014, 74 patients aged≥65years at mCRC diagnosis were identified in Bordeaux teaching hospital. Data on mCRC and comorbidities were collected from medical records. All diagnosis codes (main, related and associated) registered into the PMSI were extracted. Agreement between sources was evaluated using the percent agreement for mCRC and the kappa (κ) statistic for comorbidities. Agreement for primary CRC and mCRC was higher using all types of diagnosis codes instead of the main one exclusively (respectively 95% vs. 53% for primary CRC and 91% vs. 24% for mCRC). Agreement was substantial (κ 0.65) for cardiovascular diseases, notably atrial fibrillation (κ 0.77) and hypertension (κ 0.68). It was moderate for psychiatric disorders (κ 0.49) and respiratory diseases (κ 0.48), although chronic obstructive pulmonary disease had a good agreement (κ 0.75). Within the class of endocrine, nutritional and metabolic diseases (κ 0.55), agreement was substantial for diabetes (κ 0.91), obesity (κ 0.82) and hypothyroidism (κ 0.72) and moderate for hypercholesterolemia (κ 0.51) and malnutrition (κ 0.42). These results are reassuring with regard to detection through PMSI of mCRC if all types of diagnosis codes are considered and useful to better choose comorbidities in elderly mCRC patients that could be well identified through hospital diagnosis codes. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

Appraisal for Japan of the safety of transport of radioactive material. Provision for the application of the IAEA safety standards

International Nuclear Information System (INIS)

2006-01-01

The IAEA's Statute authorizes it to provide for the application of its standards at the request of any State. The objective of a TranSAS appraisal is to assist any requesting State to achieve a high level of safety in the transport of radioactive material by reviewing its implementation of the Transport Regulations and by making recommendations for improvement where appropriate.The IAEA discharges this statutory function through a number of mechanisms, including rendering independent peer review appraisal services to determine the status of compliance with its standards. The appraisal for Japan in December 2005 on the safety of the transport of radioactive material is the seventh TranSAS mission since the inception of the service. This report presents its findings. The TranSAS appraisal team completed a comprehensive appraisal of the implementation of the Transport Regulations in Japan. The cooperation of the authorities in Japan, and of all those who participated in the discussions, was excellent and contributed to the success of the appraisal. The comprehensive legal framework, with responsibilities identified in considerable detail and with clear lines of authority to minimize overlap of responsibilities, provides a sound basis for the implementation of the Transport Regulations. Generally, the Transport Regulations are implemented in accordance with IAEA requirements. Some areas for possible improvement have been identified. These areas relate mainly to reduction of regulations, quality management systems, training, compliance assurance and lessening the administrative burden for incorporating amendments to the IMDG Code. The findings include a considerable number of good practices, in particular in the area of maritime transport

Risk-based evaluation of allowed outage time and surveillance test interval extensions for nuclear power plants

International Nuclear Information System (INIS)

Gibelli, Sonia Maria Orlando

2008-03-01

The main goal of this work is, through the use of Probabilistic Safety Analysis (PSA), to evaluate Technical Specification (TS) Allowed Outage Times (AOT) and Surveillance Test Intervals (STI) extensions for Angra 1 nuclear power plant. PSA has been incorporated as an additional tool, required as part of NPP licensing process. The risk measure used in this work is the Core Damage Frequency (CDF), obtained from the Angra 1 PSA Level 1. AOT and STI extensions are calculated for the Safety Injection System (SIS), Service water System (SAS) and Auxiliary Feedwater System (AFS) through the use of SAPHIRE code. In order to compensate for the risk increase caused by the extensions, compensatory measures as test of redundant train prior to entering maintenance and staggered test strategy are proposed. Results have shown that the proposed AOT extensions are acceptable for the SIS and SAS with the implementation of compensatory measures. The proposed AOT extension is not acceptable for the AFS. The STI extensions are acceptable for all three systems. (author)

Feasibility of the Participatory Experience Survey and the Setting Affordances Survey for use in evaluation of programmes serving youth with intellectual and developmental disabilities.

Science.gov (United States)

Liljenquist, K; Coster, W; Kramer, J; Rossetti, Z

2017-07-01

Participation by youth with disabilities in recreational activities has been shown to promote the development of important skills needed for transition to adulthood. The Participatory Experience Survey (PES) and the Setting Affordances Survey (SAS) were developed for use by recreational programmes serving youth with significant intellectual and developmental disabilities (SIDD) to assess participant experiences and ensure that participants are afforded optimal opportunities to develop these skills. This paper presents a feasibility evaluation to determine the appropriateness of the PES and the SAS for use in a programme evaluation context. The PES and the SAS were used to evaluate a programme serving youth with SIDD in the greater northwest region of the United States. Three recreational activities were evaluated: an art project, trip to a zoo and a track practice. Programme volunteers used the SAS to assess opportunities and affordances offered within each activity. The PES was then given to 10 young people in each activity to capture their experiences. It was hypothesized that each setting would afford different experiences and developmental opportunities because of the differing nature of the activities. The PES and SAS were found to be feasible for conducting a programme evaluation. All three settings offered varying types of experiences and affordances. Notably, as measured by the SAS, opportunity for skill development was greater in more structured activities; the zoo had the fewest opportunities for skill development and the art project had the most skill development opportunities. Youth answered 'no' most often to 'asking for help' and 'helping a kid', suggesting changes to offer more opportunities to develop these skills would be beneficial in all three activities. These new instruments offer programmes a means to more fully include young people with disabilities during programme evaluations, leading to better-structured, more supportive programmes. �

The smartphone addiction scale: development and validation of a short version for adolescents.

Directory of Open Access Journals (Sweden)

Min Kwon

Full Text Available OBJECTIVE: This study was designed to investigate the revised and short version of the smartphone addiction scale and the proof of its validity in adolescents. In addition, it suggested cutting off the values by gender in order to determine smartphone addiction and elaborate the characteristics of smartphone usage in adolescents. METHOD: A set of questionnaires were provided to a total of 540 selected participants from April to May of 2013. The participants consisted of 343 boys and 197 girls, and their average age was 14.5 years old. The content validity was performed on a selection of shortened items, while an internal-consistency test was conducted for the verification of its reliability. The concurrent validity was confirmed using SAS, SAPS and KS-scale. Receiver operating characteristics analysis was conducted to suggest cut-off. RESULTS: The 10 final questions were selected using content validity. The internal consistency and concurrent validity of SAS were verified with a Cronbach's alpha of 0.911. The SAS-SV was significantly correlated with the SAS, SAPS and KS-scale. The SAS-SV scores of gender (p<.001 and self-evaluation of smartphone addiction (p<.001 showed significant difference. The ROC analysis results showed an area under a curve (AUC value of 0.963(0.888-1.000, a cut-off value of 31, sensitivity value of 0.867 and specificity value of 0.893 in boys while an AUC value of 0.947(0.887-1.000, a cut-off value of 33, sensitivity value of 0.875, and a specificity value of 0.886 in girls. CONCLUSIONS: The SAS-SV showed good reliability and validity for the assessment of smartphone addiction. The smartphone addiction scale short version, which was developed and validated in this study, could be used efficiently for the evaluation of smartphone addiction in community and research areas.

Using cognitive modeling to improve the man-machine interface

International Nuclear Information System (INIS)

Newton, R.A.; Zyduck, R.C.; Johnson, D.R.

1982-01-01

A group of utilities from the Westinghouse Owners Group was formed in early 1980 to examine the interface requirements and to determine how they could be implemented. The products available from the major vendors were examined early in 1980 and judged not to be completely applicable. The utility group then decided to develop its own specifications for a Safety Assessment System (SAS) and, later in 1980, contracted with a company to develop the system, prepare the software and demonstrate the system on a simulator. The resulting SAS is a state-of-the-art system targeted for implementation on pressurized water reactor nuclear units. It has been designed to provide control room operators with centralized and easily understandable information from a computer-based data and display system. This paper gives an overview of the SAS plus a detailed description of one of its functional areas - called AIDS. The AIDS portion of SAS is an advanced concept which uses cognitive modeling of the operator as the basis for its design

Chlorination and oxidation of sulfonamides by free chlorine: Identification and behaviour of reaction products by UPLC-MS/MS.

Science.gov (United States)

Gaffney, Vanessa de Jesus; Cardoso, Vitor Vale; Benoliel, Maria João; Almeida, Cristina M M

2016-01-15

Sulfonamides (SAs) are one class of the most widely used antibiotics around the world and have been frequently detected in municipal wastewater and surface water in recent years. Their transformation in waste water treatment plants (WWTP) and in water treatment plants (WTP), as well as, their fate and transport in the aquatic environment are of concern. The reaction of six sulfonamides (sulfamethoxazole, sulfapyridine, sulfamethazine, sulfamerazine, sulfathiazole and sulfadiazine) with free chlorine was investigated at a laboratory scale in order to identify the main chlorination by-products. A previously validated method, liquid chromatography/mass spectrometry, was used to analyse SAs and their chlorination by-products. At room temperature, pH 6-7, reaction times of up to 2 h and an initial concentration of 2 mg/L of free chlorine, the majority of SAs suffered degradation of around 65%, with the exception of sulfamethoxazole and sulfathiazole (20%). The main reaction of SAs with free chlorine occurred in the first minute. Copyright © 2015 Elsevier Ltd. All rights reserved.

The invasion history, distribution and colour pattern forms of the harlequin ladybird beetle Harmonia axyridis (Pall.) (Coleoptera, Coccinellidae) in Slovakia, Central Europe

Czech Academy of Sciences Publication Activity Database

Panigaj, L.; Zach, P.; Honěk, A.; Nedvěd, Oldřich; Kulfan, J.; Martínková, Z.; Selyemová, D.; Viglášová, S.; Roy, H. E.

-, č. 412 (2014), s. 89-102 ISSN 1313-2989 Grant - others:Slovak Research and Development Agency(SK) APVV 0200/11; Grant Agency of Ministry of Education and SAS(SK) 1/1025/12; Grant Agency of Ministry of Education and SAS(SK) 2/0035/13; Grant Agency of Ministry of Education and SAS(SK) 2/0157/11; Mze ČR(CZ) QH82047; MŠMT ČR(CZ) 7AMB12SK141; EU COST(CZ) TD1209 Program:FA Institutional support: RVO:60077344 Keywords : alien * altitude * colour morphs Subject RIV: EH - Ecology, Behaviour Impact factor: 0.933, year: 2014 http://europepmc.org/articles/PMC4042697;jsessionid=aEQnuIZkqJpBc2xpenqy.0

A sensor array system for monitoring moisture dynamics inunsaturated soil

Energy Technology Data Exchange (ETDEWEB)

Salve, R.; Cook, P.J.

2007-05-15

To facilitate investigations of moisture dynamics inunsaturated soil, we have developed a technique to qualitatively monitorpatterns of saturation changes. Field results suggest that this device,the sensor array system (SAS), is suitable for determining changes inrelative wetness along vertical soil profiles. The performance of theseprobes was compared with that of the time domain reflectometry (TDR)technique under controlled and field conditions. Measurements from bothtechniques suggest that by obtaining data at high spatial and temporalresolution, the SAS technique was effective in determining patterns ofsaturation changes along a soil profile. In addition, hardware used inthe SAS technique was significantly cheaper than the TDR system, and thesensor arrays were much easier to install along a soilprofile.

Process solutions for reducing PR residue over non-planar wafer

Science.gov (United States)

Lin, C. H.; Huang, C. H.; Yang, Elvis; Yang, T. H.; Chen, K. C.; Lu, Chih-Yuan

2011-03-01

SAS (Self-Aligned Source) process has been widely adopted on manufacturing NOR Flash devices. To form the SAS structure, the compromise between small space patterning and sufficiently removing photo resist residue in topographical substrate has been a critical challenge as the device scaling down. In this study, photo simulation, layout optimization, resist processing and tri-layer materials were evaluated to form defect-free and highly extendible SAS structure for NOR Flash devices. Photo simulation suggested more coherent light source allowed the incident light to reach the trench bottom that facilitates the removal of photo resist. Mask bias also benefited the process latitude extension for residue-free SAS printing. In the photo resist processing, both lowering the SB (Soft Bake) and raising PEB (Post-Exposure Bake) temperature of photo resist were helpful to broaden the process window but the final pattern profile was not good enough. Thermal flow for pos-exposure pattern shrinkage achieved small CD (Critical Dimension) patterning with residue-free, however the materials loading effect is another issue to be addressed at memory array boundary. Tri-layer scheme demonstrated good results in terms of free from residue, better substrate reflectivity control, enabling smaller space printing to loosen overlay specification and minimizing the poly gate clipping defect. It was finally proposed to combine with etch effort to from the SAS structure. Besides it is also promising to extend to even smaller technology nodes.

South Asian Ethnicity as a Risk Factor for Major Adverse Cardiovascular Events after Renal Transplantation

Science.gov (United States)

Vangala, Sai K.; Silver, Samuel A.; Wong, Steven C.W.; Huang, Michael; Rapi, Lindita; Nash, Michelle M.; Zaltzman, Jeffrey S.

2011-01-01

Summary Background and objectives South Asians (SAs) comprise 25% of all Canadian visible minorities. SAs constitute a group at high risk for cardiovascular disease in the general population, but the risk in SA kidney transplant recipients has never been studied. Design, setting, participants, & measurements In a cohort study of 864 kidney recipients transplanted from 1998 to 2007 and followed to June 2009, we identified risk factors including ethnicity associated with major cardiac events (MACEs, a composite of nonfatal myocardial infarction, coronary intervention, and cardiac death) within and beyond 3 months after transplant. Kaplan-Meier methodology and multivariate Cox regression analysis were used to determine risk factors for MACEs. Results There was no difference among SAs (n = 139), whites (n = 550), blacks (n = 65), or East Asians (n = 110) in baseline risk, including pre-existing cardiac disease. Post-transplant MACE rate in SAs was 4.4/100 patient-years compared with 1.31, 1.16, and 1.61/100 patient-years in whites, blacks, and East Asians, respectively (P diabetes, systolic BP, and prior cardiac disease. SAs also experienced more MACEs within 3 months after transplant compared with whites (P < 0.0001), blacks (P = 0.04), and East Asians (P = 0.006). However, graft and patient survival was similar to other groups. Conclusions SA ethnicity is an independent risk factor for post-transplant cardiac events. Further study of this high-risk group is warranted. PMID:20884776

Relations between groundwater levels and anthropogenic and meteorological stressors at selected sites in east-central Florida, 1995-2007

Science.gov (United States)

Murray, Louis C.

2010-01-01

Multivariate linear regression analyses were used to define the relations of water levels in the Upper Floridan aquifer (UFA) and surficial aquifer system (SAS) to anthropogenic and meteorological stressors between 1995 and 2007 at two monitoring well sites (Charlotte Street and Lake Oliver) in east-central Florida. Anthropogenic stressors of interest included municipal and agricultural groundwater withdrawals, and application of reclaimed-water to rapid-infiltration basins (source of aquifer recharge). Meteorological stressors included precipitation and potential evapotranspiration. Overall, anthropogenic and meteorological stressors accounted for about 40 to 89 percent of the variance in UFA and SAS groundwater levels and water-level changes. While mean monthly water levels were better correlated with monthly stressor values, changes in UFA and SAS water levels were better correlated with changes in stressor values. Water levels and water-level changes were influenced by system persistence as the moving-averaged values of both stressor types, which accounted for the influence of the previous month(s) conditions, consistently yielded higher adjusted coefficients of determination (R2 adj) values than did single monthly values. While monthly water-level changes tend to be influenced equally with both stressors across the hydrologically averaged 13-year period, changes were more influenced by one stressor or the other seasonally and during extended wet and dry periods. Seasonally, UFA water-level changes tended to be more influenced by anthropogenic stressors than by meteorological stressors, while changes in SAS water levels tended to be more influenced by meteorological stressors. During extended dry periods (12 months or greater), changes in UFA water levels at Charlotte Street were more affected by anthropogenic stressors than by meteorological stressors, while changes in SAS levels were more affected by meteorological stressors. At Lake Oliver, changes in both

A novel application of small-angle scattering techniques: Quality assurance testing of virus quantification technology

International Nuclear Information System (INIS)

Kuzmanovic, Deborah A.; Elashvili, Ilya; O'Connell, Catherine; Krueger, Susan

2008-01-01

Small-angle scattering (SAS) techniques, like small-angle X-ray scattering (SAXS) and small-angle neutron scattering (SANS), were used to measure and thus to validate the accuracy of a novel technology for virus sizing and concentration determination. These studies demonstrate the utility of SAS techniques for use in quality assurance measurements and as novel technology for the physical characterization of viruses

Tracking social motivation systems deficits: the affective neuroscience view of autism.

Science.gov (United States)

Carré, Arnaud; Chevallier, Coralie; Robel, Laurence; Barry, Caroline; Maria, Anne-Solène; Pouga, Lydia; Philippe, Anne; Pinabel, François; Berthoz, Sylvie

2015-10-01

Abnormal functioning of primary brain systems that express and modulate basic emotional drives are increasingly considered to underlie mental disorders including autism spectrum disorders. We hypothesized that ASD are characterized by disruptions in the primary systems involved in the motivation for social bonding. Twenty adults with ASD were compared to 20 neurotypical participants on the basis of self-reports and clinical assessments, including the Social Anhedonia Scale (SAS) and the Affective Neuroscience Personality Scales (ANPS). ASD diagnosis was related to SAS, as well as to positive (PLAYFULNESS) and negative (FEAR) ANPS-traits. In the overall sample, levels of autistic traits (AQ) were related to SAS and PLAYFULNESS. We argue that PLAYFULNESS could be at the root of social bonding impairments in ASD.

Recent advances in sample preparation techniques and methods of sulfonamides detection - A review.

Science.gov (United States)

Dmitrienko, Stanislava G; Kochuk, Elena V; Apyari, Vladimir V; Tolmacheva, Veronika V; Zolotov, Yury A

2014-11-19

Sulfonamides (SAs) have been the most widely used antimicrobial drugs for more than 70 years, and their residues in foodstuffs and environmental samples pose serious health hazards. For this reason, sensitive and specific methods for the quantification of these compounds in numerous matrices have been developed. This review intends to provide an updated overview of the recent trends over the past five years in sample preparation techniques and methods for detecting SAs. Examples of the sample preparation techniques, including liquid-liquid and solid-phase extraction, dispersive liquid-liquid microextraction and QuEChERS, are given. Different methods of detecting the SAs present in food and feed and in environmental, pharmaceutical and biological samples are discussed. Copyright © 2014 Elsevier B.V. All rights reserved.

CRC DEPLETION CALCULATIONS FOR THE NON-RODDED ASSEMBLIES IN BATCHES 8 AND 9 CRYSTAL RIVER UNIT 3

International Nuclear Information System (INIS)

Wilson, Michael L.

2001-01-01

The purpose of this design analysis is to document the SAS2H depletion calculations of certain non-rodded fuel assemblies from batches 8 and 9 of the Crystal River Unit 3 pressurized water reactor (PWR) that are required for Commercial Reactor Critical (CRC) evaluations to support the development of the disposal criticality methodology. A non-rodded assembly is one which never contains a control rod assembly (CRA) or an axial power shaping rod assembly (APSRA) during its irradiation history. The objective of this analysis is to provide SAS2H generated isotopic compositions for each fuel assembly's depleted fuel and depleted burnable poison materials. These SAS2H generated isotopic compositions are acceptable for use in CRC benchmark reactivity calculations containing the various fuel assemblies

Accumulation of cesium-137 by different species of plants in the zone of floods

International Nuclear Information System (INIS)

Matsko, V.P.; Gaponenko, V.I.; Sukhover, L.K.

2000-01-01

Study was carried out in some areas of Brest, Gomel and Mogilev regions suffering from periodical floods. Cesium-137 accumulation by plants of various species and families differing phylogenetically and with different root systems has been investigated. The specific activity of soil (SAS) for Cs137 varied within the range of 190...154700 Bq/kg and that of overground phytomass was within 20...28000 Bq/kg. The inverse relationship was found between SAS and the values of radionuclide accumulation factor (RAF) by plants, the correlation of SAP (Bq/kg) and SAS (Bq/kg) as well as great importance of morpho-physiological characteristics in this process. RAF in higly organized species (angiospermous) is lower than in phylogenetically older plants (lichens, mosses)

Ventajas y desventajas de la Sociedad por Acciones Simplificada para la empresa familiar en Colombia. Estudio exploratorio

Directory of Open Access Journals (Sweden)

José Bernardo Betancourt Ramírez

2013-04-01

Full Text Available La Sociedad por Acciones Simplificada (SAS representa la evolución más significativa del sistema societario colombiano en las últimas 4 décadas. Desde su aparición representa cerca del 90% del total de sociedades matriculadas en el país. Este estudio exploratorio descriptivo busca determinar si los empresarios conocen las ventajas y desventajas de las SAS, y si las tienen en cuenta en la toma de decisiones. Se aplicó un cuestionario estructurado a 57 empresas, de las cuales el 84% eran familiares. Se observó un amplio desconocimiento de algunas ventajas y desventajas de la SAS que implica el desaprovechamiento de sus bondades y, en casos puntuales, riesgos para las empresas familiares.

Ventajas y desventajas de la Sociedad por Acciones Simplificada para la empresa familiar en Colombia. Estudio exploratorio

Directory of Open Access Journals (Sweden)

José Bernardo Betancourt Ramírez

2013-01-01

Full Text Available La Sociedad por Acciones Simplificada (SAS representa la evolución más significativa del sistema societario colombiano en las últimas 4 décadas. Desde su aparición representa cerca del 90% del total de sociedades matriculadas en el país. Este estudio exploratorio descriptivo busca determinar si los empresarios conocen las ventajas y desventajas de las SAS, y si las tienen en cuenta en la toma de decisiones. Se aplicó un cuestionario estructurado a 57 empresas, de las cuales el 84% eran familia- res. Se observó un amplio desconocimiento de algunas ventajas y desventajas de la SAS que implica el desaprovechamiento de sus bondades y, en casos puntuales, riesgos para las empresas familiares.

The ASDEX integrated data analysis system AIDA

International Nuclear Information System (INIS)

Grassie, K.; Gruber, O.; Kardaun, O.; Kaufmann, M.; Lackner, K.; Martin, P.; Mast, K.F.; McCarthy, P.J.; Mertens, V.; Pohl, D.; Rang, U.; Wunderlich, R.

1989-11-01

Since about two years, the ASDEX integrated data analysis system (AIDA), which combines the database (DABA) and the statistical analysis system (SAS), is successfully in operation. Besides a considerable, but meaningful, reduction of the 'raw' shot data, it offers the advantage of carefully selected and precisely defined datasets, which are easily accessible for informative tabular data overviews (DABA), and multi-shot analysis (SAS). Even rather complicated, statistical analyses can be performed efficiently within this system. In this report, we want to summarise AIDA's main features, give some details on its set-up and on the physical models which have been used for the derivation of the processed data. We also give short introduction how to use DABA and SAS. (orig.)

CRC DEPLETION CALCULATIONS FOR THE NON-RODDED ASSEMBLIES IN BATCHES 4 AND 5 OF CRYSTAL RIVER UNIT 3

International Nuclear Information System (INIS)

Wright, Kenneth D.

1997-01-01

The purpose of this design analysis is to document the SAS2H depletion calculations of certain non-rodded fuel assemblies from batches 4 and 5 of the Crystal River Unit 3 pressurized water reactor (PWR) that are required for commercial Reactor Critical (CRC) evaluations to support the development of the disposal criticality methodology. A non-rodded assembly is one which never contains a control rod assembly (CRA) or an axial power shaping rod assembly (APSRA) during its irradiation history. The objective of this analysis is to provide SAS2H generated isotopic compositions for each fuel assembly's depleted fuel and depleted burnable poison materials. These SAS2H generated isotopic compositions are acceptable for use in CRC benchmark reactivity calculations containing the various fuel assemblies

CRC DEPLETION CALCULATIONS FOR THE NON-RODDED ASSEMBLIES IN BATCHES 1, 2, AND 3 OF CRYSTAL RIVER UNIT 3

International Nuclear Information System (INIS)

Wright, Kenneth D.

1997-01-01

The purpose of this design analysis is to document the SAS2H depletion calculations of certain non-rodded fuel assemblies from batches 1, 2, and 3 of the Crystal River Unit 3 pressurized water reactor (PWR) that are required for Commercial Reactor Critical (CRC) evaluations to support development of the disposal criticality methodology. A non-rodded assembly is one which never contains a control rod assembly (CRA) or an axial power shaping rod assembly (APSRA) during its irradiation history. The objective of this analysis is to provide SAS2H generated isotopic compositions for each fuel assembly's depleted fuel and depleted burnable poison materials. These SAS2H generated isotopic compositions are acceptable for use in CRC benchmark reactivity calculations containing the various fuel assemblies

Analysis of radiation measurement data of the BUSS cask

International Nuclear Information System (INIS)

Liu, Y.Y.; Tang, J.S.

1995-01-01

The Beneficial Uses Shipping System (BUSS) is a Type-B packaging developed for shipping nonfissile, special-form radioactive materials to facilities such as sewage, food, and medical-product irradiators. The primary purpose of the BUSS cask is to provide shielding and confinement, as well as impact, puncture, and thermal protection for its certified special-form contents under both normal transport and hypothetical accident conditions. A BUSS cask that contained 16 CsCl capsules (2.723 x 10 4 TBq total activity) was recently subjected to radiation survey measurements at a Westinghouse Hanford facility, which provided data that could be used to validate computer codes. Two shielding analysis codes, MICROSHIELD (User's Manual 1988) and SAS4 (Tan 1993), that are used at Argonne National Laboratory to evaluate the safety of packaging of radioactive materials during transportation, have been selected for analysis of radiation data obtained from the BUSS cask. MICROSHIELD, which performs only gamma radiation shielding calculation, is based on a point-kernel model with idealized geometry, whereas SAS4 is a control module in the SCALE code system (1995) that can perform three-dimensional Monte Carlo shielding calculation for photons and neutrons, with built-in procedures for cross-section data processing and automated variance reduction. The two codes differ in how they model the details of the physics of gamma photon attenuation in materials, and this difference is reflected in the associated engineering cost of the analysis. One purpose of the analysis presented in this paper, therefore, is to examine the effects of the major modeling assumptions in the two codes on calculated dose rates, and to use the measured dose rates for comparison. The focus in this paper is on analysis of radiation dose rates measured on the general body of the cask and away from penetrations

Design and application of hybrid maxillomandibular fixation for facial bone fractures.

Science.gov (United States)

Park, Kang-Nam; Oh, Seung-Min; Lee, Chang-Youn; Kim, Jwa-Young; Yang, Byoung-Eun

2013-01-01

A novel maxillomandibular fixation (MMF) procedure using a skeletal anchorage screw (SAS) (in the maxilla) and an arch bar (in the mandible), which we call "hybrid maxillomandibular fixation," was explored in this study. The aims of the study were to examine the efficacy of our hybrid MMF method and to compare periodontal tissue health and occlusal rehabilitation among 3 MMF methods. In total, 112 patients who had undergone open reduction at the Department of Oral and Maxillofacial Surgery between September 2005 and December 2012 were selected for this study. The participants were assigned to one of the following groups: SAS (maxilla), SAS (mandible), SAS-arch bar, or arch bar-arch bar. Periodontal health was evaluated using the Gingival Index, and the perioperative occlusal reproducibility was evaluated using a score of 1 to 3. Statistical analysis was performed using parametric tests (Student t test or 1-way analysis of variance followed by post hoc Tukey test). In the Gingival Index comparison performed 1 month after the surgery, only the group using the arch bars and wiring was significantly different from the other groups (P fractures. In addition, it overcomes many problems presented by previous MMF methods.

Medico-legal implications of sleep apnoea syndrome: Driving license regulations in Europe

DEFF Research Database (Denmark)

Alonderis, A.; Barbee, F.; Bonsignore, M.

2008-01-01

Background: Sleep apnoea syndrome (SAS), one of the main medical causes of excessive daytime sleepiness, has been shown to be a risk factor for traffic accidents. Treating SAS results in a normalized rate of traffic accidents. As part of the COST Action B-26, we looked at driving license regulati......Background: Sleep apnoea syndrome (SAS), one of the main medical causes of excessive daytime sleepiness, has been shown to be a risk factor for traffic accidents. Treating SAS results in a normalized rate of traffic accidents. As part of the COST Action B-26, we looked at driving license...... sleep apnoea syndrome is mentioned in 10 countries. A patient with untreated sleep apnoea is always considered unfit to drive. To recover the driving capacity, seven countries rely on a physician's medical certificate based on symptom control and compliance with therapy, whereas in two countries...... it is up to the patient to decide (on his doctor's advice) to drive again. Only FR requires a normalized electroencephalography (EEG)-based Maintenance of Wakefulness Test for professional drivers. Rare conditions (e.g., narcolepsy) are considered a driving safety risk more frequently than sleep apnoea...

Simple and sensitive monitoring of sulfonamide veterinary residues in milk by stir bar sorptive extraction based on monolithic material and high performance liquid chromatography analysis.

Science.gov (United States)

Huang, Xiaojia; Qiu, Ningning; Yuan, Dongxing

2009-11-13

A simple, rapid, and sensitive method for the quantitative monitoring of five sulfonamide antibacterial residues (SAs) in milk was developed by stir bar sorptive extraction (SBSE) coupling to high performance liquid chromatography with diode array detection. The analytes were concentrated by SBSE based on poly (vinylimidazole-divinylbenzene) monolithic material as coating. The extraction procedure was very simple, milk was diluted with water then directly sorptive extraction without elimination of fats and protein in samples was required. To achieve optimum extraction performance for SAs, several parameters, including extraction and desorption time, desorption solvent, ionic strength and pH value of sample matrix were investigated. Under the optimized experimental conditions, low detection limits (S/N=3) quantification limits (S/N=10) of the proposed method for the target compounds were achieved within the range of 1.30-7.90 ng/mL and 4.29-26.3 ng/mL from spiked milk, respectively. Good linearities were obtained for SAs with the correlation coefficients (R(2)) above 0.996. Finally, the proposed method was successfully applied to the determination of SAs compounds in different milk samples and satisfied recoveries of spiked target compounds in real samples were obtained.

Distribution of sulfonamides in liquid and solid anaerobic digestates: effects of hydraulic retention time and swine manure to rice straw ratio.

Science.gov (United States)

Jin, Hongmei; Xu, Caiyun; Du, Jing; Wu, Huashan; Huang, Hongying; Chang, Zhizhou; Xu, Yueding; Zhou, Lixiang

2017-02-01

The effects of hydraulic retention time (20 and 15 days) and swine manure to rice straw ratios on distribution of sulfonamides (SAs) in liquid and solid anaerobic digestates were studied using bench-scale completely stirred tank reactors at (37 ± 1) °C. Results showed that anaerobic digestion (AD) treatment exhibited a good removal effect on sulfadiazine (SDZ), sulfadimidine (SM2) and sulfachloropyridazine (SCP), especially at HRT = 20 days and co-digestion with swine manure and rice straw. The removal rates of SDZ and SM2 were more than 90%, but only 72.8% for SCP. The residual SAs were mainly remained in solid digestates, with residual rates ranging from 28.8% to 71.3%, 40.6% to 88.0, and 82.7% to 97.0% for SDZ, SM2 and SCP, respectively. Due to lower pKa and higher log K ow of SCP, its residue in solid digestates was far more than SDZ and SM2. Higher HRT and co-digestion could improve the degradation of SAs, which can also be put down to the occurrence of cometabolism of SAs and COD.

Factors related to self-reported social anxiety symptoms among incoming university students.

Science.gov (United States)

Cheng, Shu Hui; Sun, Zih-Jie; Lee, I Hui; Lee, Chih-Ting; Chen, Kao Chin; Tsai, Chung Hung; Yang, Yen Kuang; Yang, Yi Ching

2017-08-01

The aim of this study was to explore the lifestyle/social, personality trait and mental factors among incoming university students with higher self-reported social anxiety symptoms (SAS). A total of 5126 incoming university students were recruited. The test battery included a self-administered questionnaire that examined personal lifestyle, the Measurement of Support Functions, the Chinese Internet Addiction Scale-Revision, the Organizational Citizenship Behaviour Scale, the Social Phobia Inventory, the suicide ideation from the Brief Symptoms Rating Scale and the Pittsburgh Sleep Questionnaire. SAS (23.7%) were prevalent. Using logistic regression analysis, we found that the significant predictors of higher levels of SAS were being an undergraduate student and a non-smoker, having lower Measurement of Support Functions score (poorer social support), having higher Chinese Internet Addiction Scale-Revision score (Internet addiction), having lower Organizational Citizenship Behaviour Scale score (less altruistic behaviour), having suicide ideation and having higher Pittsburgh Sleep Questionnaire score (poorer sleeper). Given the high prevalence of SAS among university students, it is necessary to build a better strategy to detect students with potential social anxiety-related problems/disorders or other mental problems early on. © 2015 Wiley Publishing Asia Pty Ltd.

Sustainability assessment of nuclear power: Discourse analysis of IAEA and IPCC frameworks

International Nuclear Information System (INIS)

Verbruggen, Aviel; Laes, Erik

2015-01-01

Highlights: • Sustainability assessments (SAs) are methodologically precarious. • Discourse analysis reveals how the meaning of sustainability is constructed in SAs. • Discourse analysis is applied on the SAs of nuclear power of IAEA and IPCC. • For IAEA ‘sustainable’ equals ‘complying with best international practices’. • The IAEA framework largely inspires IPCC Fifth Assessment Report. - Abstract: Sustainability assessments (SAs) are methodologically precarious. Value-based judgments inevitably play a role in setting the scope of the SA, selecting assessment criteria and indicators, collecting adequate data, and developing and using models of considered systems. Discourse analysis can reveal how the meaning and operationalization of sustainability is constructed in and through SAs. Our discourse-analytical approach investigates how sustainability is channeled from ‘manifest image’ (broad but shallow), to ‘vision’, to ‘policy targets’ (specific and practical). This approach is applied on the SA frameworks used by IAEA and IPCC to assess the sustainability of the nuclear power option. The essentially problematic conclusion is that both SA frameworks are constructed in order to obtain answers that do not conflict with prior commitments adopted by the two institutes. For IAEA ‘sustainable’ equals ‘complying with best international practices and standards’. IPCC wrestles with its mission as a provider of “policy-relevant and yet policy-neutral, never policy-prescriptive” knowledge to decision-makers. IPCC avoids the assessment of different visions on the role of nuclear power in a low-carbon energy future, and skips most literature critical of nuclear power. The IAEA framework largely inspires IPCC AR5

Characteristics of Social and Administrative Sciences graduate programs and strategies for student recruitment and future faculty development in the United States.

Science.gov (United States)

Westrick, Salisa C; Kamal, Khalid M; Moczygemba, Leticia R; Breland, Michelle L; Heaton, Pamela C

2013-01-01

The rising demand of faculty in Social and Administrative Sciences (SAS) in pharmacy in the United States heightens the need to increase the number of Doctor of Philosophy (PhD) graduates in SAS who choose to pursue an academic career. To describe the characteristics of SAS graduate programs and graduate students and identify strategies for student recruitment and future faculty development. An Internet survey (phase I) with key informants (graduate program officers/department chairs) and semistructured telephone interviews (phase II) with phase I respondents were used. Items solicited data on recruitment strategies, number of students, stipends, support, and other relevant issues pertaining to graduate program administration. Descriptive statistics were tabulated. Of the 40 SAS graduate programs identified and contacted, 24 completed the Internet survey (response rate [RR]=60.0%) and, of these, 16 completed the telephone interview (RR=66.7%). At the time of the survey, the median number of graduate students with a U.S.-based PharmD degree was 3. An average annual stipend for graduate assistants was $20,825. The average time to PhD degree completion was 4.57 years, and approximately 31% of PhD graduates entered academia. Various strategies for recruitment and future faculty development were identified and documented. Findings allow SAS graduate programs to benchmark against other institutions with respect to their own achievement/strategies to remain competitive in student recruitment and development. Additional research is needed to determine the success of various recruitment strategies and identify potential new ones. Published by Elsevier Inc.

Identification and Management of Statin-Associated Symptoms in Clinical Practice: Extension of a Clinician Survey to 12 Further Countries.

Science.gov (United States)

Rosenson, Robert S; Gandra, Shravanthi R; McKendrick, Jan; Dent, Ricardo; Wieffer, Heather; Cheng, Lung-I; Catapano, Alberico L; Oh, Paul; Kees Hovingh, G; Stroes, Erik S

2017-04-01

Statins are the first-choice pharmacological treatment for patients with hypercholesterolemia and at risk for cardiovascular disease; however, a minority of patients experience statin-associated symptoms (SAS) and are considered to have reduced statin tolerance. The objective of this study was to establish how patients with SAS are identified and managed in clinical practice in Austria, Belgium, Colombia, Croatia, the Czech Republic, Denmark, Portugal, Switzerland, Russia, Saudi Arabia, Turkey, and the United Arab Emirates. A cross-sectional survey was conducted (2015-2016) among clinicians (n = 60 per country; Croatia: n = 30) who are specialized/experienced in the treatment of hypercholesterolemia. Participants were asked about their experience of patients presenting with potential SAS and how such patients were identified and treated. Muscle-related symptoms were the most common presentation of potential SAS (average: 51%; range across countries [RAC] 17-74%); other signs/symptoms included persistent elevation in transaminases. To establish whether symptoms are due to statins, clinicians required rechallenge after discontinuation of statin treatment (average: 77%; RAC 40-90%); other requirements included trying at least one alternative statin. Clinicians reported that half of high-risk patients with confirmed SAS receive a lower-dose statin (average: 53%; RAC 43-72%), and that most receive another non-statin lipid-lowering therapy with or without a concomitant statin (average: 65%; RAC 52-83%). The specialists and GPs surveyed use stringent criteria to establish causality between statin use and signs or symptoms, and persevere with statin treatment where possible.

Severe aortic stenosis patients with preserved ejection fraction according to flow and gradient classification: Prevalence and outcomes.

Science.gov (United States)

González Gómez, Ariana; Fernández-Golfín, Covadonga; Monteagudo, Juan Manuel; Izurieta, Carlos; Hinojar, Rocío; García, Ana; Casas, Eduardo; Jiménez-Nacher, José Julio; Moya, José Luis; Ruiz, Soledad; Zamorano, José Luis

2017-12-01

Clinicians often encounter patients with apparently discordant echocardiographic findings, severe aortic stenosis (SAS) defined by aortic valve area (AVA) despite a low mean gradient. A new classification according to flow state and pressure gradient has been proposed. We sought to assess the prevalence, characteristics and outcomes of patients with asymptomatic SAS with preserved left-ventricular ejection fraction (LVEF) according to flow and gradient. In total 442 patients with SAS (AVAigradient (≥ or Gradient (LF/LG): 21.3%(n=94); Normal Flow/Low Gradient (NF/LG): 32.1%(n=142); Low Flow/High Gradient (LF/HG): 6.8%(n=30); Normal Flow/High Gradient (NF/HG): 39,8%(n=176). Mean follow-up time was 20.5months (SD=10.3). Primary combined endpoint was cardiovascular mortality and hospital admission for SAS related symptom, secondary endpoint was aortic valve replacement (AVR), comparing HG group to LF/LG group. During follow-up 17 (18%) of LF/LG patients and 21 (10.2%) of HG patients met the primary endpoint. A lower free of event survival (cardiovascular mortality and hospital admission) was observed in patients with LF/LG AS (Breslow, p=0.002). Significant differences were noted between groups with a lower AVR free survival in the LF/LG group compared to HG groups (Breslow, p=0.002). Our study confirms the high prevalence and worse prognosis of LF/LG SAS. Clinicians must be aware of this entity to ensure appropriate patient management. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

Image analysis in the evaluation of the physiological potential of maize seeds1

Directory of Open Access Journals (Sweden)

Crislaine Aparecida Gomes Pinto

Full Text Available The Seed Analysis System (SAS is used in the image analysis of seeds and seedlings, and has the potential for use in the control of seed quality. The aim of this research was to adapt the methodology of image analysis of maize seedlings by SAS, and to verify the potential use of this equipment in the evaluation of the physiological potential of maize seeds. Nine batches of two maize hybrids were characterised by means of the following tests and determinations: germination, first count, accelerated ageing, cold test, seedling emergence at 25 and 30ºC, and speed of emergence index. The image analysis experiment was carried out in a factorial scheme of 9 batches x 4 methods of analysis of the seedling images (with and without the use of NWF as substrate, and with and without manual correction of the images. Images of the seedlings were evaluated using the average lengths of the coleoptile, roots and seedlings; and by the automatic and manual indices of vigour, uniformity and growth produced by the SAS. Use of blue NWF afffects the initial development of maize seedlings. The physiological potential of maize seeds can be evaluated in seedlings which are seeded on white paper towels at a temperature of 25 °C and evaluated on the third day. Image analysis should be carried out with the SAS software using automatic calibration and with no correction of the seedling images. Use of SAS equipment for the analysis of seedling images is a potential tool in evaluating the physiological quality of maize seeds.

Influence of beta blockers on survival in dogs with severe subaortic stenosis.

Science.gov (United States)

Eason, B D; Fine, D M; Leeder, D; Stauthammer, C; Lamb, K; Tobias, A H

2014-01-01

Subaortic stenosis (SAS) is one of the most common congenital cardiac defects in dogs. Severe SAS frequently is treated with a beta adrenergic receptor blocker (beta blocker), but this approach largely is empirical. To determine the influence of beta blocker treatment on survival time in dogs with severe SAS. Retrospective review of medical records of dogs diagnosed with severe, uncomplicated SAS (pressure gradient [PG] ≥80 mmHg) between 1999 and 2011. Fifty dogs met the inclusion criteria. Twenty-seven dogs were treated with a beta blocker and 23 received no treatment. Median age at diagnosis was significantly greater in the untreated group (1.2 versus 0.6 years, respectively; P = .03). Median PG at diagnosis did not differ between the treated and untreated groups (127 versus 121 mmHg, respectively; P = .2). Cox proportional hazards regression was used to identify the influence of PG at diagnosis, age at diagnosis, and beta blocker treatment on survival. In the all-cause multivariate mortality analysis, only age at diagnosis (P = .02) and PG at diagnosis (P = .03) affected survival time. In the cardiac mortality analysis, only PG influenced survival time (P = .03). Treatment with a beta blocker did not influence survival time in either the all-cause (P = .93) or cardiac-cause (P = .97) mortality analyses. Beta blocker treatment did not influence survival in dogs with severe SAS in our study, and a higher PG at diagnosis was associated with increased risk of death. Copyright © 2014 by the American College of Veterinary Internal Medicine.

A 6-year longitudinal study of predictors for suicide attempts in major depressive disorder.

Science.gov (United States)

Eikelenboom, Merijn; Beekman, Aartjan T F; Penninx, Brenda W J H; Smit, Johannes H

2018-06-13

Major depressive disorder (MDD), represent a major source of risk for suicidality. However, knowledge about risk factors for future suicide attempts (SAs) within MDD is limited. The present longitudinal study examined a wide range of putative non-clinical risk factors (demographic, social, lifestyle, personality) and clinical risk factors (depressive and suicidal indicators) for future SAs among persons with MDD. Furthermore, we examined the relationship between a number of significant predictors and the incidence of a future SA. Data are from 1713 persons (18-65 years) with a lifetime MDD at the baseline measurement of the Netherlands Study of Depression and Anxiety who were subsequently followed up 2, 4 and 6 years. SAs were assessed in the face-to-face measurements. Cox proportional hazard regression analyses were used to examine a wide range of possible non-clinical and clinical predictors for subsequent SAs during 6-year follow-up. Over a period of 6 years, 3.4% of the respondents attempted suicide. Younger age, lower education, unemployment, insomnia, antidepressant use, a previous SA and current suicidal thoughts independently predicted a future SA. The number of significant risk factors (ranging from 0 to 7) linearly predicted the incidence of future SAs: in those with 0 predictors the SA incidence was 0%, which increased to 32% incidence in those with 6+ predictors. Of the non-clinical factors, particularly socio-economic factors predicted a SA independently. Furthermore, preexisting suicidal ideation and insomnia appear to be important clinical risk factors for subsequent SA that are open to preventative intervention.

Maximum Likelihood Estimation and Inference With Examples in R, SAS and ADMB

CERN Document Server

Millar, Russell B

2011-01-01

This book takes a fresh look at the popular and well-established method of maximum likelihood for statistical estimation and inference. It begins with an intuitive introduction to the concepts and background of likelihood, and moves through to the latest developments in maximum likelihood methodology, including general latent variable models and new material for the practical implementation of integrated likelihood using the free ADMB software. Fundamental issues of statistical inference are also examined, with a presentation of some of the philosophical debates underlying the choice of statis

A DDI3.2 Style for Data and Metadata Extracted from SAS

OpenAIRE

Hoyle, Larry

2014-01-01

Earlier work by Wackerow and Hoyle has shown that DDI can be a useful medium for interchange of data and metadata among statistical packages. DDI 3.2 has new features which enhance this capability, such as the ability to use UserAttributePairs to represent custom attributes. The metadata from a statistical package can also be represented in DDI3.2 using several different styles – embedded in a StudyUnit, in a Resource Package, or in a set of Fragments. The DDI Documentation for a Fragment sta...

Bridging Numerical and Analytical Models of Transient Travel Time Distributions: Challenges and Opportunities

Science.gov (United States)

Danesh Yazdi, M.; Klaus, J.; Condon, L. E.; Maxwell, R. M.

2017-12-01

Recent advancements in analytical solutions to quantify water and solute time-variant travel time distributions (TTDs) and the related StorAge Selection (SAS) functions synthesize catchment complexity into a simplified, lumped representation. While these analytical approaches are easy and efficient in application, they require high frequency hydrochemical data for parameter estimation. Alternatively, integrated hydrologic models coupled to Lagrangian particle-tracking approaches can directly simulate age under different catchment geometries and complexity at a greater computational expense. Here, we compare and contrast the two approaches by exploring the influence of the spatial distribution of subsurface heterogeneity, interactions between distinct flow domains, diversity of flow pathways, and recharge rate on the shape of TTDs and the relating SAS functions. To this end, we use a parallel three-dimensional variably saturated groundwater model, ParFlow, to solve for the velocity fields in the subsurface. A particle-tracking model, SLIM, is then implemented to determine the age distributions at every real time and domain location, facilitating a direct characterization of the SAS functions as opposed to analytical approaches requiring calibration of such functions. Steady-state results reveal that the assumption of random age sampling scheme might only hold in the saturated region of homogeneous catchments resulting in an exponential TTD. This assumption is however violated when the vadose zone is included as the underlying SAS function gives a higher preference to older ages. The dynamical variability of the true SAS functions is also shown to be largely masked by the smooth analytical SAS functions. As the variability of subsurface spatial heterogeneity increases, the shape of TTD approaches a power-law distribution function, including a broader distribution of shorter and longer travel times. We further found that larger (smaller) magnitude of effective

CRC DEPLETION CALCULATIONS FOR THE NON-RODDED ASSEMBLIES IN BATCHES 4 AND 5 OF CRYSTAL RIVER UNIT 3

Energy Technology Data Exchange (ETDEWEB)

Kenneth D. Wright

1997-07-30

The purpose of this design analysis is to document the SAS2H depletion calculations of certain non-rodded fuel assemblies from batches 4 and 5 of the Crystal River Unit 3 pressurized water reactor (PWR) that are required for commercial Reactor Critical (CRC) evaluations to support the development of the disposal criticality methodology. A non-rodded assembly is one which never contains a control rod assembly (CRA) or an axial power shaping rod assembly (APSRA) during its irradiation history. The objective of this analysis is to provide SAS2H generated isotopic compositions for each fuel assembly's depleted fuel and depleted burnable poison materials. These SAS2H generated isotopic compositions are acceptable for use in CRC benchmark reactivity calculations containing the various fuel assemblies.

Small-angle scattering in materials science

International Nuclear Information System (INIS)

Paris, O.; Fratzl, P.

1999-01-01

Small-angle scattering (SAS) of X-rays (SAXS) or neutrons (SANS) are a powerful tools to investigate inhomogeneities in the size range from ∼ 1 nm to ∼ 100 nm. Typical examples in materials science are pores, precipitates in metal alloys or nano-particles in composites. Frequently, these inhomogeneities are not spherical and their alignment is not random, quite in contrast to many other applications of SAS. This requires the use of pinhole geometry and area detectors for the experimental set-up. The present paper focuses on evaluation techniques of two-dimensional (2D) SAS-patterns from some materials investigated by the authors, i.e. metal alloys, carbon composites, wood and bone. Although the examples shown are derived exclusively from SAXS measurements, most of them could stem from SANS measurements as well. (author)

Safeguards and Security FY 1996 Program Plan: WBS 6.6

International Nuclear Information System (INIS)

Lee, F.D.

1995-08-01

The Safeguards and Security (SAS) Program is based upon integrity, competence and innovation in the protection of the public and Hanford resources through: (1) outstanding assistance, oversight, education, and counsel to their customers to ensure the protection of the public, site personnel, assets, and information; (2) value-added and cost-effective solutions to Hanford issues; and (3) risk management techniques to ensure effective asset protection, site accessibility, and the flexibility to adapt to changing customer needs. This plan is divided into two parts: overview and SAS WBS (work breakdown structure) dictionary sheets. The overview is divided into vision and mission, goals and objectives, assumptions and priorities, milestones, and a summary. The SAS WBS dictionary sheets are divided into department overhead, general and administrative, sitewide support, Hanford patrol, traffic safety, and locksmith services

Database dictionary for the results of groundwater tracer tests using tritiated water, conducted at the Oak Ridge National Laboratory

Energy Technology Data Exchange (ETDEWEB)

Thompson, B.K. [Univ. of Tennessee, Knoxville, TN (United States). Dept. of Civil Engineering; Huff, D.D. [Oak Ridge National Lab., TN (United States). Environmental Sciences Div.

1997-05-01

In 1977, the United States Geological Survey (USGS) conducted two tracer tests at the Oak Ridge National Laboratory (ORNL) using tritiated water to study the relative importance of bedding-plane openings on shallow groundwater flow. Through a cooperative agreement between the USGS and the US Department of Energy (DOE), the data were made available to researchers at the Oak Ridge National Laboratory (ORNL), who organized the data into a data management format. The results of these groundwater tracer tests have been compiled into a collection of four SAS data sets. This report documents these SAS data sets, including their structure, methodology, and content. The SAS data sets include information on precipitation, tritium, water levels, and well construction for wells at or near ORNL radioactive waste burial grounds 4, 5, and 6.

Safeguards and Security FY 1996 Program Plan: WBS 6.6

Energy Technology Data Exchange (ETDEWEB)

Lee, F.D.

1995-08-01

The Safeguards and Security (SAS) Program is based upon integrity, competence and innovation in the protection of the public and Hanford resources through: (1) outstanding assistance, oversight, education, and counsel to their customers to ensure the protection of the public, site personnel, assets, and information; (2) value-added and cost-effective solutions to Hanford issues; and (3) risk management techniques to ensure effective asset protection, site accessibility, and the flexibility to adapt to changing customer needs. This plan is divided into two parts: overview and SAS WBS (work breakdown structure) dictionary sheets. The overview is divided into vision and mission, goals and objectives, assumptions and priorities, milestones, and a summary. The SAS WBS dictionary sheets are divided into department overhead, general and administrative, sitewide support, Hanford patrol, traffic safety, and locksmith services.

A Rapid and Inexpensive Bioassay to Evaluate the Decontamination of Organophosphates

Science.gov (United States)

2012-01-01

nition, early attempts at CWA decontamination included washing with soap and water, absorbing with Fuller’s earth, and simply leaving the chemicals to...quires sophisticated instrumental analytical techniques such as liquid or gas chromatography, which involves expensive equipment and trained personnel...Data were analyzed using the PROC ANOVA proce - dure in the SAS 9.2 software (SAS Institute Inc, Cary, NC). The models were used to describe the

An Integration, Long Range Planning, and Migration Guide for the Stock Point Logistics Integrated Communications Project.

Science.gov (United States)

1986-03-01

and universal terminal/printer interface mapping ( TMAP ) software. When the Burroughs HYPERchannel software package (i.e., Burroughs NETEX) provided...and terminal device and security functions placed under the control of the FDC’s SAS/ TMAP processes. Without processing efficiency enhancements, TAPS...FDC’s SAS/ TMAP processes. As was also previously indicated, the performance of TAPS II on TANDEM is poor today, and there are questions as whether

Prediction of Outcome After Emergency High-Risk Intra-abdominal Surgery Using the Surgical Apgar Score

DEFF Research Database (Denmark)

Cihoric, Mirjana; Toft Tengberg, Line; Bay-Nielsen, Morten

2016-01-01

BACKGROUND: With current literature quoting mortality rates up to 45%, emergency high-risk abdominal surgery has, compared with elective surgery, a significantly greater risk of death and major complications. The Surgical Apgar Score (SAS) is predictive of outcome in elective surgery, but has nev...... emergency high-risk abdominal surgery. Despite its predictive value, the SAS cannot in its current version be recommended as a standalone prognostic tool in an emergency setting....

Evaluating Coding Accuracy in General Surgery Residents' Accreditation Council for Graduate Medical Education Procedural Case Logs.

Science.gov (United States)

Balla, Fadi; Garwe, Tabitha; Motghare, Prasenjeet; Stamile, Tessa; Kim, Jennifer; Mahnken, Heidi; Lees, Jason

The Accreditation Council for Graduate Medical Education (ACGME) case log captures resident operative experience based on Current Procedural Terminology (CPT) codes and is used to track operative experience during residency. With increasing emphasis on resident operative experiences, coding is more important than ever. It has been shown in other surgical specialties at similar institutions that the residents' ACGME case log may not accurately reflect their operative experience. What barriers may influence this remains unclear. As the only objective measure of resident operative experience, an accurate case log is paramount in representing one's operative experience. This study aims to determine the accuracy of procedural coding by general surgical residents at a single institution. Data were collected from 2 consecutive graduating classes of surgical residents' ACGME case logs from 2008 to 2014. A total of 5799 entries from 7 residents were collected. The CPT codes entered by residents were compared to departmental billing records submitted by the attending surgeon for each procedure. Assigned CPT codes by institutional American Academy of Professional Coders certified abstract coders were considered the "gold standard." A total of 4356 (75.12%) of 5799 entries were identified in billing records. Excel 2010 and SAS 9.3 were used for analysis. In the event of multiple codes for the same patient, any match between resident codes and billing record codes was considered a "correct" entry. A 4-question survey was distributed to all current general surgical residents at our institution for feedback on coding habits, limitations to accurate coding, and opinions on ACGME case log representation of their operative experience. All 7 residents had a low percentage of correctly entered CPT codes. The overall accuracy proportion for all residents was 52.82% (range: 43.32%-60.07%). Only 1 resident showed significant improvement in accuracy during his/her training (p = 0

Genotoxic effects of synthetic amorphous silica nanoparticles in the mouse lymphoma assay

Directory of Open Access Journals (Sweden)

Eşref Demir

Full Text Available Synthetic amorphous silica nanoparticles (SAS NPs have been used in various industries, such as plastics, glass, paints, electronics, synthetic rubber, in pharmaceutical drug tablets, and a as food additive in many processed foods. There are few studies in the literature on NPs using gene mutation approaches in mammalian cells, which represents an important gap for genotoxic risk estimations. To fill this gap, the mouse lymphoma L5178Y/Tk+/− assay (MLA was used to evaluate the mutagenic effect for five different concentrations (from 0.01 to 150 μg/mL of two different sizes of SAS NPs (7.172 and 7.652 nm and a fine collodial form of silicon dioxide (SiO2. This assay detects a broad spectrum of mutational events, from point mutations to chromosome alterations. The results obtained indicate that the two selected SAS NPs are mutagenic in the MLA assay, showing a concentration-dependent effect. The relative mutagenic potencies according to the induced mutant frequency (IMF are as follows: SAS NPs (7.172 nm (IMF = 705.5 × 10−6, SAS NPs (7.652 nm (IMF = 575.5 × 10−6, and SiO2 (IMF = 57.5 × 10−6. These in vitro results, obtained from mouse lymphoma cells, support the genotoxic potential of NPs as well as focus the discussion of the benefits/risks associated with their use in different areas. Keywords: Synthetic amorphous silica nanoparticles, Mouse lymphoma assay, Mutagenic agents, Thymidine kinase (Tk gene, In vitro mutagenicity

Vulnerability of a public supply well in a karstic aquifer to contamination.

Science.gov (United States)

Katz, B G; McBride, W S; Hunt, A G; Crandall, C A; Metz, P A; Eberts, S M; Berndt, M P

2009-01-01

To assess the vulnerability of ground water to contamination in the karstic Upper Floridan aquifer (UFA), age-dating tracers and selected anthropogenic and naturally occurring compounds were analyzed in multiple water samples from a public supply well (PSW) near Tampa, Florida. Samples also were collected from 28 monitoring wells in the UFA and the overlying surficial aquifer system (SAS) and intermediate confining unit located within the contributing recharge area to the PSW. Age tracer and geochemical data from the earlier stage of the study (2003 through 2005) were combined with new data (2006) on concentrations of sulfur hexafluoride (SF(6)), tritium ((3)H), and helium-3, which were consistent with binary mixtures of water for the PSW dominated by young water (less than 7 years). Water samples from the SAS also indicated mostly young water (less than 7 years); however, most water samples from monitoring wells in the UFA had lower SF(6) and (3)H concentrations than the PSW and SAS, indicating mixtures containing high proportions of older water (more than 60 years). Vulnerability of the PSW to contamination was indicated by predominantly young water and elevated nitrate-N and volatile organic compound concentrations that were similar to those in the SAS. Elevated arsenic (As) concentrations (3 to 19 microg/L) and higher As(V)/As(III) ratios in the PSW than in water from UFA monitoring wells indicate that oxic water from the SAS likely mobilizes As from pyrite in the UFA matrix. Young water found in the PSW also was present in UFA monitoring wells that tap a highly transmissive zone (43- to 53-m depth) in the UFA.

Reduced left precentral regional responses in patients with major depressive disorder and history of suicide attempts.

Science.gov (United States)

Tsujii, Noa; Mikawa, Wakako; Tsujimoto, Emi; Adachi, Toru; Niwa, Atsushi; Ono, Hisae; Shirakawa, Osamu

2017-01-01

Previous neuroimaging studies have revealed frontal and temporal functional abnormalities in patients with major depressive disorder (MDD) and a history of suicidal behavior. However, it is unknown whether multi-channel near-infrared spectroscopy (NIRS) signal changes among individuals with MDD are associated with a history of suicide attempts and a diathesis for suicidal behavior (impulsivity, hopelessness, and aggression). Therefore, we aimed to explore frontotemporal hemodynamic responses in depressed patients with a history of suicide attempts using 52-channel NIRS. We recruited 30 patients with MDD and a history of suicidal behavior (suicide attempters; SAs), 38 patient controls without suicidal behavior (non-attempters; NAs), and 40 healthy controls (HCs) matched by age, gender ratio, and estimated IQ. Regional hemodynamic responses during a verbal fluency task (VFT) were monitored using NIRS. Our results showed that severities of depression, impulsivity, aggression, and hopelessness were similar between SAs and NAs. Both patient groups had significantly reduced activation compared with HCs in the bilateral frontotemporal regions. Post hoc analyses revealed that SAs exhibited a smaller hemodynamic response in the left precentral gyrus than NAs and HCs. Furthermore, the reduced response in the left inferior frontal gyrus was negatively correlated with impulsivity level and hemodynamic responses in the right middle frontal gyrus were negatively associated with hopelessness and aggression in SAs but not in NAs and HCs. Our findings suggest that MDD patients with a history of suicide attempts demonstrate patterns of VFT-induced NIRS signal changes different from those demonstrated by individuals without a history of suicidal behaviors, even in cases where clinical symptoms are similar. NIRS has a relatively high time resolution, which may help visually differentiate SAs from NAs.

Security Transition Program Office (STPO), technology transfer of the STPO process, tools, and techniques

Energy Technology Data Exchange (ETDEWEB)

Hauth, J.T.; Forslund, C.R.J.; Underwood, J.A.

1994-09-01

In 1990, with the transition from a defense mission to environmental restoration, the U.S. Department of Energy`s (DOE`s) Hanford Site began a significant effort to diagnose, redesign, and implement new safeguards and security (SAS) processes. In 1992 the Security Transition Program Office (STPO) was formed to address the sweeping changes that were being identified. Comprised of SAS and other contractor staff with extensive experience and supported by staff experienced in organizational analysis and work process redesign, STPO undertook a series of tasks designed to make fundamental changes to SAS processes throughout the Hanford Site. The goal of STPO is to align the SAS work and organization with the new Site mission. This report describes the key strategy, tools, methods, and techniques used by STPO to change SAS processes at Hanford. A particular focus of this review is transferring STPO`s experience to other DOE sites and federal agency efforts: that is, to extract, analyze, and provide a critical review of the approach, tools, and techniques used by STPO that will be useful to other DOE sites and national laboratories in transitioning from a defense production mode to environmental restoration and other missions. In particular, what lessons does STPO provide as a pilot study or model for implementing change in other transition activities throughout the DOE complex? More broadly, what theoretical and practical contributions do DOE transition efforts, such as STPO, provide to federal agency streamlining efforts and attempts to {open_quotes}reinvent{close_quotes} government enterprises in the public sector? The approach used by STPO should provide valuable information to those examining their own processes in light of new mission requirements.

Sleep apnea syndrome. Examination of pharyngeal obstruction with high-speed MR and polysomnography

International Nuclear Information System (INIS)

Suto, Y.; Inoue, Y.

1995-01-01

We attempted to determine the usefulness of high-speed MR imaging for evaluating the severity of sleep apnea syndrome (SAS) by comparing findings of pharyngeal obstruction obtained with high-speed MR with those of all-night polysomnography (PSG). A total of 33 patients with SAS underwent turbo-FLASH MR examination, while awake and after i.v. injection of hydroxyzine hydrochloride. Serial images were examined by cinemode. Pharyngeal findings on MR were divided into single-site obstruction (SO) at the velopharynx, multiple-site obstruction (MO), and no obstruction (NO). PSG findings were analyzed to determine the predominant type of apnea, severity as evaluated by an apnea index (AI), and the lowest SaO 2 value during sleep. Seventy-five percent of the central apnea group had SO, and 70% of the mixed apneas had MO, while only 15% of the obstructed apneas had MO. The percentage of patients with severe SAS (AI of 20% or higher) was 48% for the SO, and 70% for the MO. The lowest SaO 2 value tended to be low in the mixed apnea in the case of PSG, and tended to be low in the MO at MR examination. Analysis of pharyngeal dynamics using high-speed MR may provide some useful information for evaluating the severity of SAS. (orig.)

Depression and anxiety in patients with oral squamous cell carcinoma

Institute of Scientific and Technical Information of China (English)

无

2006-01-01

PURPOSE: The aim of this study was to investigate symptoms of depression and anxiety in the patients with oral squamous cell carcinoma (OSCC). METHODS: 76 patients with oral squamous cell carcinoma participated in this program. All patients were rated with the self-rating anxiety scale (SAS) and the self-rating depression scale (SDS). The mean scores of SAS and SDS were compared to those scores of the Norm of Chinese people. In addition, the different treatment results of the patients with different levels of anxiety and depression were studied. Further, the number of patients of SAS, SDS with more than 50 score were compared between primary cancer patients and recurrent cancer patients. RESULTS: The scores of SAS, SDS and the number of patients with more than 50 score in the patients group were obviously higher than those in Chinese Norm (P＜0.01).The levels of anxiety and depression in 32 patients with recurrent cancer were more severe than those of 44 patients with primary cancer. The patients with anxiety and/or depression showed poor prognosis. CONCLUSION: Anxiety and depression are common symptoms in patients with OSCC and have negative effects on the prognosis, thus the psychological intervention for the patients must be carried out.

A Method for Estimating Costs and Benefits of Space Assembly and Servicing By Astronauts and Robots

Science.gov (United States)

Purves, Lloyd R.; Benfield, Mark (Technical Monitor)

2002-01-01

One aspect of designing future space missions is to determine whether Space Assembly and Servicing (SAS) is useful and, if so, what combination of robots and astronauts provides the most effective means of accomplishing it. Certain aspects of these choices, such as the societal value of developing the means for humans to live in space, do not lend themselves to quantification. However, other SAS costs and benefits can be quantified in a manner that can help select the most cost-effective SAS approach. Any space facility, whether it is assembled and serviced or not, entails an eventual replacement cost due to wear and obsolescence. Servicing can reduce this cost by limiting replacement to only failed or obsolete components. However, servicing systems, such as space robots, have their own logistics cost, and astronauts can have even greater logistics requirements. On the other hand, humans can be more capable than robots at performing dexterous and unstructured tasks, which can reduce logistics costs by allowing a reduction in mass of replacement components. Overall, the cost-effectiveness of astronaut SAS depends on its efficiency; and, if astronauts have to be wholly justified by their servicing usefulness, then the serviced space facility has to be large enough to fully occupy them.

Exploring the functional significance of sterol glycosyltransferase enzymes.

Science.gov (United States)

Singh, Gaurav; Dhar, Yogeshwar Vikram; Asif, Mehar Hasan; Misra, Pratibha

2018-01-01

Steroidal alkaloids (SAs) are widely synthesized and distributed in plants manifesting as natural produce endowed with potential for medicinal, pesticidal and other high-value usages. Glycosylation of these SAs raises complex and diverse glycosides in plant cells that indeed govern numerous functional aspects. During the glycosylation process of these valuable metabolites, the addition of carbohydrate molecule(s) is catalyzed by enzymes known as sterol glycosyltransferases (SGTs), commonly referred to as UGTs, leading to the production of steryl glycosides (SGs). The ratio of SGs and nonglyco-conjugated SAs are different in different plant species, however, their biosynthesis in the cell is controlled by different environmental factors. The aim of this review is to evaluate the current SGT enzyme research and the functional consequences of glycomodification of SAs on the physiology and plant development, which together are associated with the plant's primary processes. Pharmaceutical, industrial, and other potential uses of saponins have also been discussed and their use in therapeutics has been unveiled by in silico analysis. The field of biotransformation or conversion of nonglycosylated to glycosylated phytosterols by the activity of SGTs, making them soluble, available and more useful for humankind is the new field of interest towards drug therapy. Copyright © 2017 Elsevier Ltd. All rights reserved.

Experimental investigation and oral bioavailability enhancement of nano-sized curcumin by using supercritical anti-solvent process.

Science.gov (United States)

Anwar, Mohammed; Ahmad, Iqbal; Warsi, Musarrat H; Mohapatra, Sharmistha; Ahmad, Niyaz; Akhter, Sohail; Ali, Asgar; Ahmad, Farhan J

2015-10-01

The biomedical applications of curcumin (CUR) are limited due to its poor oral bioavailability. In this work, CUR nanoparticles were successfully prepared by combining the supercritical anti-solvent (SAS) process with Tween 80 as a solubilizing agent and permeation enhancer. Different processing parameters that can govern the mean particle size and size distribution of nanoparticles were well investigated by manipulating the types of solvents, mixing vessel pressure, mixing vessel temperature, CO2 flow rate, solution flow rate and solution concentration. Solid state characterization was done by Fourier Transform infrared spectroscopy, differential scanning calorimetry, dynamic light scattering, scanning electron microscopy, and powder X-ray diffraction study. Solubility and dissolution profile of SAS-processed CUR were found to be significantly increased in comparison with native CUR. Further, a validated ultra-performance liquid chromatographic method with quadrupole-time of flight-mass spectrometry was developed to investigate the pharmacokinetic parameters after a single oral dose (100mg/kg) administration of CUR (before/after SAS-processed) in male Wistar rats. From the plasma concentration vs. time profile graph, oral bioavailability of SAS-processed CUR was found to be increased approximately 11.6-fold (p<0.001) as compared to native CUR. Copyright © 2015 Elsevier B.V. All rights reserved.

Prevalência de uso de recursos ergogênicos em praticantes de musculação na cidade de João Pessoa, Paraíba

Directory of Open Access Journals (Sweden)

Fabiana Ranielle de Siqueira Nogueira

2015-03-01

Full Text Available Este artigo determina a prevalência e o perfil dos usuários de Esteroides Anabólicos Androgênicos (EAAs e Suplementos Alimentares (SAs da cidade de João Pessoa, Paraíba (PB. Os dados foram coletados por questionário estruturado. Foram analisados 510 sujeitos (24,9±6,2 anos, sendo 79,4% (n=405 do sexo masculino. A prevalência de uso de EAAs e SAs foi de 20,6% (n=105 e 55,5% (n=283, respectivamente. Os usuários eram majoritariamente homens, jovens, com baixa escolaridade e que treinavam havia mais de quatro anos com frequência de cinco vezes por semana. Esses dados demonstram que há elevada prevalência de uso de EAAs e SAs por parte de praticantes de atividade física em academias na cidade analisada.

SmartApps: Middle-ware for Adaptive Applications on Reconfigurable Platforms

Energy Technology Data Exchange (ETDEWEB)

Lawrence Rauchwerger

2009-08-09

There are several reasons why the performance of current distributed and heterogeneous systems is often disappointing. For example, the characteristics of the application may be input sensitive and evolve during execution causing dramatic changes in memory reference patterns, resource requirements, or degree of concurrency between different phases of the computation. Or, the system may change dynamically with nodes failing or appearing, some network links severed and other links established with different latencies and bandwidths. Another important reason for poor performance is the fairly compartmentalized approach to optimization: applications, compilers, operating systems and hardware configurations are designed and optimized in isolation and without the knowledge of instance specific information and needs of a running application. There is too little information flow across these boundaries and no global optimization is even attempted. For example, most operating systems services like paging, virtual-to-physical page mapping, I/O, or data layout in disks, provide little or no application customization. Similarly, the off-the-shelf hardware used by most commercial systems is optimized to give best average-case performance. To address this problem, we have proposed application-centric computing, or Smart Applications (SAS). In the SAS executable, the compiler embeds most run-time system services, and a performance-optimizing feedback loop that monitors the application's performance and adaptively reconfigures the application and the OS/system platform. At run-time, after incorporating the code's input and determining the system's resources and state, the SAS performs an *instance* specific optimization, which is more tractable than a global generic optimization between application, OS and system. The overriding philosophy of SAS is ``measure, compare, and adapt if beneficial.'' That is, the application will continually monitor its

E-Cigarette Social Media Messages: A Text Mining Analysis of Marketing and Consumer Conversations on Twitter

OpenAIRE

Lazard, Allison J; Saffer, Adam J; Wilcox, Gary B; Chung, Arnold DongWoo; Mackert, Michael S; Bernhardt, Jay M

2016-01-01

Background As the use of electronic cigarettes (e-cigarettes) rises, social media likely influences public awareness and perception of this emerging tobacco product. Objective This study examined the public conversation on Twitter to determine overarching themes and insights for trending topics from commercial and consumer users. Methods Text mining uncovered key patterns and important topics for e-cigarettes on Twitter. SAS Text Miner 12.1 software (SAS Institute Inc) was used for descriptiv...

The evaluation of isotopic composition for TRIGA 14 MW spent fuel

International Nuclear Information System (INIS)

Covaci, St.; Toma, C.; Preda, M.

2008-01-01

In the summer of 1999 year, a first shipment of TRIGA HEU spent fuel to INEEL U.S.A. has taken place. he TRIGA HEU fuel was burned in the TRIGA steady state 14 MW reactor between 1980 and 1996 years. At the moment of prepared documentation for the shipment (July 1999), the evaluation of isotopic composition was calculated with ORIGEN-2 code with an irradiation history adequately prepared. Subsequently (May - June 2000), the evaluation was repeated with SAS2H module of SCALE 4.4a system. In the paper the results and the comparisons of the codes are presented, and the accuracy and convenient application of SCALE 4.4a system are emphasized. (authors)

Visual in-pile fuel disruption experiments

International Nuclear Information System (INIS)

Cano, G.L.; Ostensen, R.W.; Young, M.F.

1978-01-01

In a loss-of-flow (LOF) accident in an LMFBR, the mode of disruption of fuel may determine the probability of a subsequent energetic excursion. To investigate these phenomena, in-pile disruption of fission-heated irradiated fuel pellets was recorded by high speed cinematography. Instead of fuel frothing or dust-cloud breakup (as used in the SAS code) massive and very rapid fuel swelling, not predicted by analytical models, occurred. These tests support massive fuel swelling as the initial mode of fuel disruption in a LOF accident. (author)

[Social and cultural representations in epilepsy awareness].

Science.gov (United States)

Arborio, Sophie

2015-01-01

Representations relating to epilepsy have evolved over the centuries, but the manifestations of epilepsy awaken archaic images linked to death, violence and disgust. Indeed, the generalised epileptic seizure symbolises a rupture with the surrounding environment, "informs it", through the loss of social codes which it causes. The social and cultural context, as well as medical knowledge, influences the representations of the disease. As a result, popular knowledge is founded on the social and cultural representations of a given era, in a given society. Copyright © 2015 Elsevier Masson SAS. All rights reserved.