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Sample records for sara cyclotron

  1. using SARA analysis

    Directory of Open Access Journals (Sweden)

    Oscar Ramirez

    2015-01-01

    Full Text Available La solubilidad del CO2 en un crudo pesado colombiano fue calculada usando la ecuación cúbica de estado de Peng-Robinson y la correlación de Lee-Kesler. El crudo fue representado como una mezcla de pseudo-componentes y para cada uno de ellos se calcularon las propiedades termodinámicas y críticas. Los resultados obtenidos en la representación del crudo con cuatro, cinco y seis pseudocomponentes muestran que todas las representaciones producen resultados similares y por lo tanto el uso de cuatro pseudo-componentes es suficiente y tiene un costo computacional más bajo. Fueron obtenidos excelentes resultados al comparar los datos experimentales y calculados. Para este sistema es suficiente tener una completa caracterización del análisis SARA y usar cuatro pseudo-componentes para modelar adecuadamente el equilibrio líquido-vapor de CO2-crudo pesado.

  2. The SARA REU Site Program

    Science.gov (United States)

    Wood, M. A.; Oswalt, T. D.; SARA Collaboration

    2000-12-01

    We present an overview of the Research Experiences for Undergraduates (REU) Site Program hosted by the Southeastern Association for Research in Astronomy (SARA) for the past 6 years. SARA is a consortium of the six universities: Florida Institute of Technology, East Tennessee State University, Florida International University, The University of Georgia, Valdosta State University, and Clemson University. We host 10-11 student interns per year out of an application pool of ~150-200. Recruiting flyers are sent to the ~3400 undergraduate institutions in the United States, and we use a web-based application form and review process. We are a distributed REU Site, but come together for group meetings at the beginning and end of the summer program and stay in contact in between using email list manager software. Interns complete a research project working one-on-one with a faculty mentor, and each intern travels to observe at the SARA Observatory at Kitt Peak National Observatory. Interns give both oral and display presentations of their results at the final group meeting. In addition, all interns write a paper for publication in the IAPPP Communications, an international amateur-professional journal, and several present at professional meetings and in refereed publications. We include in the group meetings a ``how-to'' session on giving talks and posters, an Ethics Session, and a session on Women in Astronomy. This work was supported by the NSF Research Experiences for Undergraduates (REU) Site Program through grant AST 96169939 to The Florida Institute of Technology.

  3. Experience with the SARA OSL method

    DEFF Research Database (Denmark)

    Mejdahl, V.; Bøtter-Jensen, L.

    1997-01-01

    The paper describes our experience using the single aliquot regeneration added dose (SARA) OSL method during a 2-yr period for dating archaeological and geological materials. The principle of the method is outlined and a simple method for testing whether a possible sensitivity change depends...... on the added dose is shown. Advantages of the SARA method is discussed and results obtained using this method for 15 archaeological samples are compared with TL results. A correlation coefficient of 0.967 was found. The test also included comparison of a SARA dare with an archaeomagnetic date for a brick kiln...

  4. Severe Accident Recriticality Analyses (SARA)

    Energy Technology Data Exchange (ETDEWEB)

    Frid, W. [Swedish Nuclear Power Inspectorate, Stockholm (Sweden); Hoejerup, F. [Risoe National Lab. (Denmark); Lindholm, I.; Miettinen, J.; Puska, E.K. [VTT Energy, Helsinki (Finland); Nilsson, Lars [Studsvik Eco and Safety AB, Nykoeping (Sweden); Sjoevall, H. [Teoliisuuden Voima Oy (Finland)

    1999-11-01

    Recriticality in a BWR has been studied for a total loss of electric power accident scenario. In a BWR, the B{sub 4}C control rods would melt and relocate from the core before the fuel during core uncovery and heat-up. If electric power returns during this time-window unborated water from ECCS systems will start to reflood the partly control rod free core. Recriticality might take place for which the only mitigating mechanisms are the Doppler effect and void formation. In order to assess the impact of recriticality on reactor safety, including accident management measures, the following issues have been investigated in the SARA project: 1. the energy deposition in the fuel during super-prompt power burst, 2. the quasi steady-state reactor power following the initial power burst and 3. containment response to elevated quasi steady-state reactor power. The approach was to use three computer codes and to further develop and adapt them for the task. The codes were SIMULATE-3K, APROS and RECRIT. Recriticality analyses were carried out for a number of selected reflooding transients for the Oskarshamn 3 plant in Sweden with SIMULATE-3K and for the Olkiluoto 1 plant in Finland with all three codes. The core state initial and boundary conditions prior to recriticality have been studied with the severe accident codes SCDAP/RELAP5, MELCOR and MAAP4. The results of the analyses show that all three codes predict recriticality - both superprompt power bursts and quasi steady-state power generation - for the studied range of parameters, i. e. with core uncovery and heat-up to maximum core temperatures around 1800 K and water flow rates of 45 kg/s to 2000 kg/s injected into the downcomer. Since the recriticality takes place in a small fraction of the core the power densities are high which results in large energy deposition in the fuel during power burst in some accident scenarios. The highest value, 418 cal/g, was obtained with SIMULATE-3K for an Oskarshamn 3 case with reflooding

  5. Exon: CBRC-SARA-01-1228 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1228 ATGTGgttttgctgttgttcttttctactgtggggatcaagcctgggtctccTATATGCAAGCCA...TAATATGCCCCGCCCTGCAGCTgtgtttttccctccctccctcccagctttccttccttccttccttccttccttccttccttccttccttccttccttccttccttccttccttccttccttccttccttcc...ttccttccttccttccttccttccttccttcctgccttccttcctgccttcctgccttccttcctccctcccttcctcccttccttcctgccttccttcctccctcc...cttcctcccttccttcctccctcccttccttccttccttccttccttccttccttccttccttccttccttccttccttcc...ttccttccttccttccttccttccttcctcccttcctgccttcctgccttttttccttttttctttttcttcctgtctgtctgt

  6. Poems by a suicide: Sara Teasdale.

    Science.gov (United States)

    Lester, David; McSwain, Stephanie

    2010-06-01

    An analysis of trends over time in the poems of Sara Teasdale as the time of her suicide approached identified a decrease in positive emotions and fewer references to the self and to others. These trends are different from those previously identified from studies of letters and diaries written by suicides.

  7. CLOVERLEAF CYCLOTRON

    Science.gov (United States)

    McMillan, E.M.; Judd, D.L.

    1959-02-01

    A cyclotron is presented embodying a unique magnetic field configuration, which configuration increases in intensity with radius and therefore compensates for the reltivistic mass effect, the field having further convolutions productive of axial stability in the particle beam. By reconciling the seemingly opposed requirements of mass increase compensation on one hand and anial stability on the other, the production of extremely high current particle beams in the relativistie energy range is made feasible. Certain further advantages inhere in the invention, notably an increase in the usable magnet gap, simplified and more efficient extraction of the beam from the accelerator, and ready adaptation to the use of multiply phased excitation as contrasted with the single phased systems herstofore utilized. General

  8. Cyclotron waves in plasma

    CERN Document Server

    Lominadze, D G

    2013-01-01

    Cyclotron Waves in Plasma is a four-chapter text that covers the basic physical concepts of the theory of cyclotron waves and cyclotron instabilities, brought about by the existence of steady or alternating plasma currents flowing perpendicular to the magnetic field.This book considers first a wide range of questions associated with the linear theory of cyclotron oscillations in equilibrium plasmas and in electron plasmas in metals and semiconductors. The next chapter deals with the parametric excitation of electron cyclotron oscillations in plasma in an alternating electric field. A chapter f

  9. ELECTRON CYCLOTRON WAVES

    NARCIS (Netherlands)

    Westerhof, E.

    2010-01-01

    This lecture gives an overview of heating and current drive with electron cyclotron waves. We present the main theoretical aspects of wave propagation, wave absorption, and non-inductive current drive, as well as important technical aspects for the application of high power electron cyclotron waves,

  10. Electron cyclotron waves

    NARCIS (Netherlands)

    Westerhof, E.

    2012-01-01

    This lecture gives an overview of heating and current drive with electron cyclotron waves. We present the main theoretical aspects of wave propagation, wave absorption, and non-inductive current drive, as well as important technical aspects for the application of high power electron cyclotron waves,

  11. Electron cyclotron waves

    NARCIS (Netherlands)

    Westerhof, E.

    2008-01-01

    This lecture gives an overview of heating and current drive with electron cyclotron waves. We present the main theoretical aspects of wave propagation, wave absorption, and non-inductive current drive, as well as important technical aspects for the application of high power electron cyclotron waves,

  12. Synchro-cyclotron

    CERN Multimedia

    CERN PhotoLab

    1972-01-01

    The electromagnetic coil which forms the first section of the proton extraction channel in the improved synchro-cyclotron. The photograph shows the positioning gear and the current septum. An extraction efficiency above 50% is expected.

  13. Research, Teaching, and Outreach with the SARA Remote Observatory

    Science.gov (United States)

    Keel, William

    2009-11-01

    Our use of the SARA remote-operated observatories ranges from the classroom, through public outreach sessions, to graduate and faculty research. Teaching applications include enrichment sessions for freshman classes, and data-taking sessions for students in upper-level lab courses where they can derive asteroid distances, ages of star clusters, and properties of eclipsing binary systems. Graduate students can enrich their observational experience, where SARA forms a useful bridge between a modern, small campus observatory and the larger facilities many will use for dissertation research. Some students use the SARA facilities as the backbone of theses or dissertations; in one example, the student obtained all the ground-based data she needed to supplement Hubble images using SARA within a single year. Faculty research benefits from the regular access and (often) quick availability of these modestly- sized telescopes. I will show some examples of follow-up from the Galaxy Zoo public- participation project in which SARA results were the first available confirming or path-finding data (in cases of a quasar light echo and extended ionized clouds around active galaxies). Regular access allows the telescope's use in a ``screening'' fashion for surveys. Finally, the depth of images quickly available with such instruments lends itself to powerful public-outreach opportunities, with images taken ``by request.'' One such session (at DragonCon in Atlanta) was able to satisfy requests for gravitational lenses, two dwarf planets, supernova remnants, and a dwarf galaxy in one session.

  14. The relationship between SARA fractions and crude oil stability

    Directory of Open Access Journals (Sweden)

    Siavash Ashoori

    2017-03-01

    Full Text Available Asphaltene precipitation and deposition are drastic issues in the petroleum industry. Monitoring the asphaltene stability in crude oil is still a serious problem and has been subject of many studies. To investigate crude oil stability by saturate, aromatic, resin and asphaltene (SARA analysis seven types of crudes with different components were used. The applied methods for SARA quantification are IP-143 and ASTM D893-69 and the colloidal instability index (CII is computed from the SARA values as well. In comparison between CII results, the values of oil compositions demonstrated that the stability of asphaltenes in crude oils is a phenomenon that is related to all these components and it cannot be associated only with one of them, individually.

  15. Layering of life (Sara novel of Peter Sarić

    Directory of Open Access Journals (Sweden)

    Kostić Dragomir J.

    2015-01-01

    Full Text Available Novel Sara of Petar Sarić consists of two parts; in it are processed or present two wars, two major wars in the region of Montenegro and Herzegovina, the First and Second World War. However, it is more novel about divisions within the family and the man himself, (and infamous assault of godfather Luka on Sarah also and his murder are in that function, in the first part; and on the divisions among the people, in general, in the second part of the novel. The second part is, in fact, the image layering of life, not a symbolic one, full of hope, faith, reliance, rather than a concrete, real life, that life which is transformed into a fear of life. Separate, poetical, part of the novel, is his main character, Sara. It is no coincidence that her name novel entitled. Because she is one of most beautiful characters in the newer Serbian prose. Speech about the Sara precedes speech about her book. The book is Sara, Sara's book! Possession of book is her main feature of the exterior. Sara comes out from the Book and disappears in the book. Self contained and independent, therefore doomed to conflict with the environment. Loyal to husband and family, loyal to the truth and for justice, she ,,not hurt anything and anyone, no one is standing in the way, to anyone not wroth, nor has anyone looked wrong.' At the same time, the strange beauty, beauty that could not fit into some sort of scheme, one particular image or idea of beauty that again and again renewed, changed, remaining distant, and unmet. Strange goodness, marvelous beauty, she suffered unusual way; her life was transformed into continuous abstinence, repression, in anxiety and fear. In a word: in martirizam! Finally, in order to safe­guard children, sacrificed herself. Novel is a strong critique of society which is not able to recognize the beauty / goodness!.

  16. Production of cyclotron radionuclides

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Yong Sup; Lim, Sang Moo; Yang, Seung Dae; Chun, Kwon Soo; Ahn, Soon Hyuk; Yun, Yong Kee; Park, Hyun; Lee, Ji Sup; Lee, Jong Doo; Chai, Jong Seo; Kim, Yoo Seok; Hong, Sung Suk; Lee, Min Yong; Beak, Seung Ki [Korea Cancer Center Hospital, Seoul (Korea)

    1999-12-01

    In the project, 11,492mCi of {sup 201}Tl, 4,384mCi of {sup 67}Ga, 1,245mCi of {sup 123}l, 523mCi of [{sup 123}I]mlBG and 1,283mCi of {sup 18}FDG were supplied, and the revenue were 304,723,000won. In the production of RI, 13 deg for {sup 201}Tl and {sup 67}Ga, 45 deg for {sup 123}l angle solid target have been used, and liquid target system has been used for {sup 18}F production. For the efficient use of the cyclotron, the MC-50 cyclotron was opened to outside user and basic research project was carried out. The technical supports and radionuclides analysis were done during the execution of the research. Then the facilities of safety supervision and handling techniques of radioisotope production were improved. 7 refs., 9 figs., 8 tabs. (Author)

  17. Production of cyclotron radionuclides

    Energy Technology Data Exchange (ETDEWEB)

    Chun, Kwon Soo; Lim, Sang Moo; Yang, Seung Dae; Suh, Yong Sup; Ahn, Soon Hyuk; Yun, Yong Kee; Park, Hyun; Lee, Ji Sup; Chai, Jong Seo; Kim, Yoo Seok; Hong, Sung Suk; Lee, Min Yong; Beak, Seung Ki; Kim, Jang Hye; Kim, Gi Sup [Korea Cancer Center Hospital, Seoul (Korea)

    2000-12-01

    In the project, 12,077mCi of {sup 201}Tl, 5,717mCi of {sup 67}Ga, 2,096mCi of {sup 123}l, 482mCi of [{sup 123}I]mlBG and 2,738mCi of {sup 18}FDG were supplied, and the revenue were 387,253,000won. In the production of RI, 13 deg for {sup 201}Tl and {sup 67}Ga, 45 deg for {sup 123}l angle solid target have been used, and liquid target system has been used for {sup 18}F production. For the efficient use of the cyclotron, the MC-50 cyclotron was opened to outside user and basic research project was carried out. The technical supports and radionuclides analysis were done during the execution of the research. Then the facilities of safety supervision and handling techniques of radioisotope production were improved. 7 refs., 8 figs., 9 tabs. (Author)

  18. Subacute ruminal acidosis (SARA) challenge, ruminal condition and cellular immunity in cattle.

    Science.gov (United States)

    Sato, Shigeru

    2015-02-01

    Subacute ruminal acidosis (SARA) is characterized by repeated bouts of low ruminal pH. Cows with SARA often develop complications or other diseases, and associate physiologically with immunosuppression and inflammation. Ruminal free lipopolysaccharide (LPS) increases during SARA and translocates into the blood circulation activating an inflammatory response. Ruminal fermentation and cellular immunity are encouraged by supplementing hay with calf starter during weaning. SARA calves given a 5-day repeated administration of a bacteria-based probiotic had stable ruminal pH levels (6.6-6.8). The repeated administration of probiotics enhance cellular immune function and encourage recovery from diarrhea in pre-weaning calves. Furthermore, the ruminal fermentation could guard against acute and short-term feeding changes, and changes in the rumen microbial composition of SARA cattle might occur following changes in ruminal pH. The repeated bouts of low ruminal pH in SARA cattle might be associated with depression of cellular immunity.

  19. Teologi Politik Berbalu SARA Antara Ambisi dan Konspirasi

    Directory of Open Access Journals (Sweden)

    M. Sidi Ritau'din

    2017-06-01

    Full Text Available In a multi-cultural democracy based on Pancasila philosophy of independence, ethnic, religious, racial and intergroup issues it call (SARA are political indicators that can trigger conflict and division. If the player is ambitious and power-hungry, then he will not hesitate to do everything he can to gain power, even build a big conspiracy using SARA as a tool to divide the ummah, then he emerges as a unifier and presents programs prestigious sympathetic, there Imaging actions and slogans of the pro poor people, but essentially no more as political deceit, a false gift of hope, it familiar said (PHP that never realized, only reap the political advantage in the game of SARA, even not hesitate to shout thief when he Itself is a thieving thief based on greed and greed where the horizontal relations of fellow human beings deny the bond of faith as the foundation. Political conspiracy based on political interests and abuse of power, an action of political pathology that is not civilized that has become a trend of contemporary politics and globalization.

  20. Population structure of rumen Escherichia coli associated with subacute ruminal acidosis (SARA) in dairy cattle.

    Science.gov (United States)

    Khafipour, E; Plaizier, J C; Aikman, P C; Krause, D O

    2011-01-01

    Previous studies indicated that only subacute ruminal acidosis (SARA), induced by feeding a high-grain diet, is associated with an inflammatory response and increased abundance of Escherichia coli in the rumen. We hypothesized that ruminal E. coli in grain pellet-induced SARA carried virulence factors that potentially contribute to the immune activation during SARA. One hundred twenty-nine E. coli isolates were cultured from the rumens of 8 cows (4 animals per treatment) in which SARA had been nutritionally induced by feeding a high-grain diet (GPI-SARA) or a diet containing alfalfa pellets (API-SARA). The population structure of the E. coli was evaluated with the ABD genotyping system and repetitive sequence-based (rep)-PCR fingerprinting. Twenty-five virulence factors were evaluated with PCR. Escherichia coli numbers were higher in the GPI-SARA treatment than in the API-SARA treatment. The genetic structure of the E. coli was significantly different between SARA challenge models. Isolates from GPI-control (46%), API-control (70%), and API-SARA (53%) were closely related and fell into one cluster, whereas isolates from GPI-SARA (54%) grouped separately. The ABD typing indicated a shift from an A-type E. coli population to a B1-type population only due to GPI-SARA. Of the 25 virulence factors tested, curli fiber genes were highly associated with GPI. Curli fibers were first identified in E. coli mastitis isolates and are potent virulence factors that induce a range of immune responses. Results suggest that under low rumen pH conditions induced by a grain diet, there is a burst in the number of E. coli with virulence genes that can take advantage of these rumen conditions to trigger an inflammatory response. Copyright © 2011 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  1. Pathophysiological evaluation of subacute ruminal acidosis (SARA) by continuous ruminal pH monitoring.

    Science.gov (United States)

    Sato, Shigeru

    2016-02-01

    Evaluation of the radio-transmission pH-measurement system for monitoring the ruminal pH and subacute ruminal acidosis (SARA) in cattle is described. This is done in order to reveal the possible application of this system for detection and pathophysiological research of SARA by continuous ruminal pH measurement. The possibility of using this system for assessment of the ruminal pH in SARA cattle, and the presence of negative correlation between the ruminal pH and ruminal temperature in heathy and SARA cattle were determined. In addition, the 16S rRNA gene pyrosequencing analysis showed that the ruminal microbial community was simpler in SARA cattle, and the bacterial numbers in SARA cattle were lower than those in healthy hay-fed cattle. Concentrate feeding might have reduced the diversity of the ruminal microbial community. Changes in the ruminal microbial community of SARA cattle might be related to the changes in ruminal pH followed by the decrease in the number of some bacteria. Continuous monitoring of the ruminal pH using the radio-transmission pH-measurement system would be applied for detection and prevention of SARA in the field and pathophysiological research of SARA, including ruminal zymology and bacteriology, which have been determined previously by sampling of the ruminal fluid and measuring of ruminal pH. © 2015 The Authors. Animal Science Journal published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Society of Animal Science.

  2. Cyclotrons and positron emitting radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Wolf, A.P.; Fowler, J.S.

    1984-01-01

    The state of the art of Positron Emission Tomography (PET) technology as related to cyclotron use and radiopharmaceutical production is reviewed. The paper discusses available small cyclotrons, the positron emitters which can be produced and the yields possible, target design, and radiopharmaceutical development and application. 97 refs., 12 tabs. (ACR)

  3. Ion cyclotron resonance cell

    Science.gov (United States)

    Weller, R.R.

    1995-02-14

    An ion cyclotron resonance cell is disclosed having two adjacent sections separated by a center trapping plate. The first section is defined by the center trapping plate, a first end trapping plate, and excitation and detector electrodes. The second section includes a second end trapping plate spaced apart from the center plate, a mirror, and an analyzer. The analyzer includes a wavelength-selective light detector, such as a detector incorporating an acousto-optical device (AOD) and a photodetector. One or more ion guides, grounded plates with holes for the ion beam, are positioned within the vacuum chamber of the mass spectrometer between the ion source and the cell. After ions are trapped and analyzed by ion cyclotron resonance techniques in the first section, the ions of interest are selected according to their mass and passed into the second section for optical spectroscopic studies. The trapped ions are excited by light from a laser and caused thereby to fluoresce. The fluorescent light emitted by the excited ions is reflected by the mirror and directed onto the detector. The AOD is scanned, and the photodetector output is recorded and analyzed. The ions remain in the second section for an extended period, enabling multiple studies to be carried out on the same ensemble of ions. 5 figs.

  4. Low energy neutral atom imaging on the Moon with the SARA ...

    Indian Academy of Sciences (India)

    This paper reports on the Sub-keV Atom Reflecting Analyzer (SARA) experiment that will be flown on the first Indian lunar mission Chandrayaan-1. The SARA is a low energy neutral atom. (LENA) imaging mass spectrometer, which will perform remote sensing of the lunar surface via detection of neutral atoms in the energy ...

  5. EC-5 fifth international workshop on electron cyclotron emission and electron cyclotron heating

    Energy Technology Data Exchange (ETDEWEB)

    Prater, R.; Lohr, J. [eds.

    1985-12-31

    This report contains papers on the following topics: electron cyclotron emission measurements; electron cyclotron emission theory; electron cyclotron heating; gyrotron development; and ECH systems and waveguide development. These paper have been indexed separately elsewhere. (LSP).

  6. Ion Cyclotron Resonance Facility (ICR)

    Data.gov (United States)

    Federal Laboratory Consortium — his facility is charged with developing and exploiting the unique capabilities of Fourier Transform Ion Cyclotron Resonance (FT-ICR) mass spectrometry, and leads the...

  7. BEST medical radioisotope production cyclotrons

    Energy Technology Data Exchange (ETDEWEB)

    Sabaiduc, Vasile; Milton, Bruce; Suthanthiran, Krishnan; Johnson, Richard R. [Best Cyclotron Systems Inc., 7-8765 Ash Street, Vancouver, British Columbia, V6P 6T3 (Canada); Gelbart, W. Z. [Advanced System Designs Inc., 5295 Bear Bay Road, Garden Bay, BC, V0N 1S1 (Canada)

    2013-04-19

    Best Cyclotron Systems Inc (BCSI) is currently developing 14 MeV, 25 MeV, 35MeV and 70MeV cyclotrons for radioisotope production and research applications as well as the entire spectrum of targets and nuclear synthesis modules for the production of Positron Emission Tomography (PET), Single Photon Emission Computed Tomography (SPECT) and radiation therapy isotopes. The company is a subsidiary of Best Medical International, renowned in the field of medical instrumentation and radiation therapy. All cyclotrons have external negative hydrogen ion sources, four radial sectors with two dees in opposite valleys, cryogenic vacuum system and simultaneous beam extraction on opposite lines. The beam intensity ranges from 400 {mu}A to 1000 {mu}A, depending on the cyclotron energy and application.

  8. Cyclotron for Beam Therapy Application

    CERN Document Server

    Alenitsky, Yu G; Karamysheva, G A; Kostromin, S A; Mitsyn, G V; Molokanov, A G; Onishchenko, L M; Samsonov, E V; Vorozhtsov, S B; Zaplatin, N L

    2005-01-01

    The basic parameters of the proton isochronous cyclotron on the fixed energy are considered. The energy of protons is $E_{p}\\sim $ 220~MeV, intensity of the extracted beam is $I_{p}\\sim $ 0.1~$\\mu$A. The cyclotron is projected on the basis of compact magnet with four sectors and the diameter of poles 300 cm. Two dees of the accelerating system are located in valleys.

  9. Multicavity proton cyclotron accelerator

    Directory of Open Access Journals (Sweden)

    J. L. Hirshfield

    2002-08-01

    Full Text Available A mechanism for acceleration of protons is described, in which energy gain occurs near cyclotron resonance as protons drift through a sequence of rotating-mode TE_{111} cylindrical cavities in a strong nearly uniform axial magnetic field. Cavity resonance frequencies decrease in sequence from one another with a fixed frequency interval Δf between cavities, so that synchronism can be maintained between the rf fields and proton bunches injected at intervals of 1/Δf. An example is presented in which a 122 mA, 1 MeV proton beam is accelerated to 961 MeV using a cascade of eight cavities in an 8.1 T magnetic field, with the first cavity resonant at 120 MHz and with Δf=8 MHz. Average acceleration gradient exceeds 40 MV/m, average effective shunt impedance is 223 MΩ/m, but maximum surface field in the cavities does not exceed 7.2 MV/m. These features occur because protons make many orbital turns in each cavity and thus experience acceleration from each cavity field many times. Longitudinal and transverse stability appear to be intrinsic properties of the acceleration mechanism, and an example to illustrate this is presented. This acceleration concept could be developed into a proton accelerator for a high-power neutron spallation source, such as that required for transmutation of nuclear waste or driving a subcritical fission burner, provided a number of significant practical issues can be addressed.

  10. Staphylococcus aureus sarA Regulates Inflammation and Colonization during Central Nervous System Biofilm Formation

    Science.gov (United States)

    Snowden, Jessica N.; Beaver, Matt; Beenken, Karen; Smeltzer, Mark; Horswill, Alexander R.; Kielian, Tammy

    2013-01-01

    Infection is a frequent and serious complication following the treatment of hydrocephalus with CSF shunts, with limited therapeutic options because of biofilm formation along the catheter surface. Here we evaluated the possibility that the sarA regulatory locus engenders S. aureus more resistant to immune recognition in the central nervous system (CNS) based on its reported ability to regulate biofilm formation. We utilized our established model of CNS catheter-associated infection, similar to CSF shunt infections seen in humans, to compare the kinetics of bacterial titers, cytokine production and inflammatory cell influx elicited by wild type S. aureus versus an isogenic sarA mutant. The sarA mutant was more rapidly cleared from infected catheters compared to its isogenic wild type strain. Consistent with this finding, several pro-inflammatory cytokines and chemokines, including IL-17, CXCL1, and IL-1β were significantly increased in the brain following infection with the sarA mutant versus wild type S. aureus, in agreement with the fact that the sarA mutant displayed impaired biofilm growth and favored a planktonic state. Neutrophil influx into the infected hemisphere was also increased in the animals infected with the sarA mutant compared to wild type bacteria. These changes were not attributable to extracellular protease activity, which is increased in the context of SarA mutation, since similar responses were observed between sarA and a sarA/protease mutant. Overall, these results demonstrate that sarA plays an important role in attenuating the inflammatory response during staphylococcal biofilm infection in the CNS via a mechanism that remains to be determined. PMID:24386336

  11. Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation.

    Directory of Open Access Journals (Sweden)

    Jessica N Snowden

    Full Text Available Infection is a frequent and serious complication following the treatment of hydrocephalus with CSF shunts, with limited therapeutic options because of biofilm formation along the catheter surface. Here we evaluated the possibility that the sarA regulatory locus engenders S. aureus more resistant to immune recognition in the central nervous system (CNS based on its reported ability to regulate biofilm formation. We utilized our established model of CNS catheter-associated infection, similar to CSF shunt infections seen in humans, to compare the kinetics of bacterial titers, cytokine production and inflammatory cell influx elicited by wild type S. aureus versus an isogenic sarA mutant. The sarA mutant was more rapidly cleared from infected catheters compared to its isogenic wild type strain. Consistent with this finding, several pro-inflammatory cytokines and chemokines, including IL-17, CXCL1, and IL-1β were significantly increased in the brain following infection with the sarA mutant versus wild type S. aureus, in agreement with the fact that the sarA mutant displayed impaired biofilm growth and favored a planktonic state. Neutrophil influx into the infected hemisphere was also increased in the animals infected with the sarA mutant compared to wild type bacteria. These changes were not attributable to extracellular protease activity, which is increased in the context of SarA mutation, since similar responses were observed between sarA and a sarA/protease mutant. Overall, these results demonstrate that sarA plays an important role in attenuating the inflammatory response during staphylococcal biofilm infection in the CNS via a mechanism that remains to be determined.

  12. Indicators of induced subacute ruminal acidosis (SARA) in Danish Holstein cows.

    Science.gov (United States)

    Danscher, Anne Mette; Li, Shucong; Andersen, Pia H; Khafipour, Ehsan; Kristensen, Niels B; Plaizier, Jan C

    2015-07-17

    The prevalence of subacute ruminal acidosis (SARA) in dairy cows is high with large impact on economy and welfare. Its current field diagnosis is based on point ruminal pH measurements by oral probe or rumenocentesis. These techniques are invasive and inaccurate, and better markers for the diagnosis of SARA are needed. The goal of this study was to evaluate clinical signs of SARA and to investigate the use of blood, faecal and urinary parameters as indicators of SARA. Six lactating, rumen cannulated, Danish Holstein cows were used in a cross-over study with three periods. The first and second periods included two cows on control diet and two cows on nutritional SARA challenge. The third period only included two cows on SARA challenge. Control diet was a conventional total mixed ration [45.5% dry matter (DM), 17.8% crude protein, 43.8% neutral detergent fibre, and 22.5% acid detergent fibre (DM basis)]. SARA challenge was conducted by substituting control diet with grain pellets (50% wheat/barley) over 3 days to reach 40% grain in the diet. Ruminal pH was measured continuously. Blood samples were collected once daily at 7 h after feeding. Samples of faeces and urine were collected at feeding, and at 7 and 12 h after feeding. Blood samples were analysed for pCO2, pO2, pH, electrolytes, lactate, glucose, packed cell volume (PCV), and total plasma protein concentration. Milk composition, ruminal VFA, and pH of faeces and urine were measured. SARA was associated with decreased (P < 0.05) minimum ruminal, faecal and urinary pH. Daily times and areas of ruminal pH below 5.8, and 5.6 were increased to levels representative for SARA. Significant differences were detected in milk composition and ruminal VFAs. Blood calcium concentration was decreased (P < 0.05), and pCO2 tended to be increased (P = 0.10). Significant differences were not detected in other parameters. SARA challenge was associated with changes in faecal and urinary pH, blood calcium concentration and

  13. PDB: CBRC-SARA-01-0838 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0838 3ODU,3OE0,3OE6,3OE8,3OE9, Region:8-324(Identity=89%) PDB:3ODU Chain:A (X-ray Resolution...=2.5),Region:8-324(Identity=89%) PDB:3OE0 Chain:A (X-ray Resolution=2.9),Region:8-330(...Identity=90%) PDB:3OE6 Chain:A (X-ray Resolution=3.2),Region:8-324(Identity=89%) PDB:3OE8 Chain:A (X-ray Resolution...=3.1),Region:8-324(Identity=89%) PDB:3OE9 Chain:A (X-ray Resolution=3.1), ...

  14. Le Cendrillon ‘en morceaux’ de Sara Fanelli

    Directory of Open Access Journals (Sweden)

    Geneviève Guétemme

    2010-12-01

    Full Text Available Sara Fanelli illustre Cendrillon avec une boîte en carton, un livret, dix‐huit cartes postales et des timbres. Cette ‘illustration’, sous forme de ‘boîte à trésor’ dont le ‘lecteur’ va pouvoir étaler le contenu, privilégie le découpage, le ‘vrac’ et les images ‘en morceaux’. Comment se positionne cet objet par rapport aux textes de Perrault et de Grimm ? Les images et le livret nous parlent‐ils du même texte ? Le morcellement génère‐t‐il sa propre ‘magie’ ? En quoi cette illustration vient‐elle questionner le conte : son récit, ses origines et sa lecture ?

  15. Sara, a patient with borderline personality structure: A "crisis" management

    Directory of Open Access Journals (Sweden)

    Paola Marinelli

    2015-05-01

    Full Text Available In this article the author examines some significant passages of his treatment of a patient with borderline personality structure, with the intention of giving a formative contribution to the delicate issue of the search for congruence between theory and clinic operations. This reflection is therefore an opportunity to integrate these aspects. The individualization of the therapeutic relationship in the theoretical framework of group analysis allowed the emotional investment in the person of the therapist, which is useful in the construction of a meaningful relationship on the human, emotional and cognitive plane; a space within which it has become increasingly possible for Sara, share and process emotions, re-build, contact parts of the self frustrated and disappointed, perceive less and less the void and become less vulnerable, being able to pull over to the original trauma. 

  16. MC-50 AVF cyclotron operation

    Energy Technology Data Exchange (ETDEWEB)

    Chae, Jong Seo; Lee, Dong Hoon; Kim, You Seok; Park, Chan Won; Lee, Yong Min; Hong, Sung Seok; Lee, Min Yong

    1995-12-01

    The first cyclotron in Korea, MC-59 cyclotron is used for neutron irradiation, radionuclide development, production and material and biomedical research. 50.5MeV and 35MeV proton beam have been extracted with 20-70 .mu.A. A total of beam extraction time are 1095.7 hours. 206.5 hours are used for the developments and 663.8 hours are for radionuclide production and development and 225.4 hours for application researches. The shutdown days are 23days. Fundamental data for failure decrement and efficient beam extraction were composed and maintenance technologies were developed. (author). 8 tabs., 17 figs., 10 refs.

  17. MC-50 AVF cyclotron operation

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yu Seok; Chai, Jong Seo; Bak, Seong Ki; Park, Chan Won; Jo, Young Ho; Hong, Seong Seok; Lee, Min Yong; Jang Ho Ha

    2000-01-01

    The first cyclotron in Korea, MC-50 cyclotron is used for neutron irradiation, radionuclide development, production and material and biomedical research. 50.5MeV and 35MeV proton beam have been extracted with 20-60{mu}A. A total of beam extraction time are 1095.7 hours. 206.5 hours are used for the developments and 663.8 hours are for radionuclide production and development and 225.4 hours for application researches. The shutdown days are 23 days. Fundamental data for failure decrement and efficient beam extraction were composed and maintenance technologies were developed.

  18. The new species of Mysidacea (Crustacea), Anchialina labatus and Gastrosaccus sarae, from south west Australia

    Digital Repository Service at National Institute of Oceanography (India)

    Panampunnayil, S.U.

    on the third segment of the mandibular palp and by the modification of the exopod of the third pleopod of the male. G. sarae is distinguished from the other species by the shape and armature of the telson...

  19. The Remote Observatories of the Southeastern Association for Research in Astronomy (SARA)

    OpenAIRE

    Keel, William C.; Oswalt, Terry; Mack, Peter; Henson, Gary; Hillwig, Todd; Batcheldor, Daniel; Berrington, Robert; De Pree, Chris; Hartmann, Dieter; Leake, Martha; Licandro, Javier; Murphy, Brian; Webb, James; Wood, Matt A.

    2016-01-01

    We describe the remote facilities operated by the Southeastern Association for Research in Astronomy (SARA), a consortium of colleges and universities in the US partnered with Lowell Observatory, the Chilean National Telescope Allocation Committee, and the Instituto de Astrofisica de Canarias. SARA observatories comprise a 0.96m telescope at Kitt Peak, Arizona; a 0.6m instrument on Cerro Tololo, Chile; and the 1m Jacobus Kapteyn Telescope at the Roque de los Muchachos, La Palma, Spain. All ar...

  20. Diagnosis of subacute ruminal acidosis (SARA) by continuous reticular pH measurements in cows.

    Science.gov (United States)

    Sato, Shigeru; Ikeda, Aya; Tsuchiya, Yoshiyuki; Ikuta, Kentaro; Murayama, Isao; Kanehira, Masahiro; Okada, Keiji; Mizuguchi, Hitoshi

    2012-09-01

    The objective of this study was to determine whether subacute ruminal acidosis (SARA) could be diagnosed by continuous measurements of the reticular pH, as compared with the ruminal pH, using healthy cows fed a control diet and SARA cows fed a rumen acidosis-inducing diet. The reticular and ruminal pH were measured simultaneously by a radio transmission pH measurement system. The mean reticular pH at 1-h intervals decreased gradually from the morning feeding to the next feeding time in both healthy and SARA cows, though the decrease in the ruminal pH was observed to be more drastic as compared with that observed in the reticular pH. The threshold of the 1-h mean pH in the reticulum for a diagnosis of SARA was considered to be 6.3, and a significant positive correlation was observed between the reticular and ruminal pH. No differences in the concentrations of lactic acid, ammonia nitrogen, and volatile fatty acids were noted between the reticular and ruminal fluids in SARA cows. These results demonstrate that the reticular pH can be used to detect SARA in cows, as opposed to using the ruminal pH.

  1. SARA - SURE/ASSIST RELIABILITY ANALYSIS WORKSTATION (UNIX VERSION)

    Science.gov (United States)

    Butler, R. W.

    1994-01-01

    SARA, the SURE/ASSIST Reliability Analysis Workstation, is a bundle of programs used to solve reliability problems. The mathematical approach chosen to solve a reliability problem may vary with the size and nature of the problem. The Systems Validation Methods group at NASA Langley Research Center has created a set of four software packages that form the basis for a reliability analysis workstation, including three for use in analyzing reconfigurable, fault-tolerant systems and one for analyzing non-reconfigurable systems. The SARA bundle includes the three for reconfigurable, fault-tolerant systems: SURE reliability analysis program (COSMIC program LAR-13789, LAR-14921); the ASSIST specification interface program (LAR-14193, LAR-14923), and PAWS/STEM reliability analysis programs (LAR-14165, LAR-14920). As indicated by the program numbers in parentheses, each of these three packages is also available separately in two machine versions. The fourth package, which is only available separately, is FTC, the Fault Tree Compiler (LAR-14586, LAR-14922). FTC is used to calculate the top-event probability for a fault tree which describes a non-reconfigurable system. PAWS/STEM and SURE are analysis programs which utilize different solution methods, but have a common input language, the SURE language. ASSIST is a preprocessor that generates SURE language from a more abstract definition. ASSIST, SURE, and PAWS/STEM are described briefly in the following paragraphs. For additional details about the individual packages, including pricing, please refer to their respective abstracts. ASSIST, the Abstract Semi-Markov Specification Interface to the SURE Tool program, allows a reliability engineer to describe the failure behavior of a fault-tolerant computer system in an abstract, high-level language. The ASSIST program then automatically generates a corresponding semi-Markov model. A one-page ASSIST-language description may result in a semi-Markov model with thousands of states and

  2. Cyclotron transitions of bound ions

    Science.gov (United States)

    Bezchastnov, Victor G.; Pavlov, George G.

    2017-06-01

    A charged particle in a magnetic field possesses discrete energy levels associated with particle rotation around the field lines. The radiative transitions between these levels are the well-known cyclotron transitions. We show that a bound complex of particles with a nonzero net charge displays analogous transitions between the states of confined motion of the entire complex in the field. The latter bound-ion cyclotron transitions are affected by a coupling between the collective and internal motions of the complex and, as a result, differ from the transitions of a "reference" bare ion with the same mass and charge. We analyze the cyclotron transitions for complex ions by including the coupling within a rigorous quantum approach. Particular attention is paid to comparison of the transition energies and oscillator strengths to those of the bare ion. Selection rules based on integrals of collective motion are derived for the bound-ion cyclotron transitions analytically, and the perturbation and coupled-channel approaches are developed to study the transitions quantitatively. Representative examples are considered and discussed for positive and negative atomic and cluster ions.

  3. Social humanoid robot SARA: development of the wrist mechanism

    Science.gov (United States)

    Penčić, M.; Rackov, M.; Čavić, M.; Kiss, I.; Cioată, V. G.

    2018-01-01

    This paper presents the development of a wrist mechanism for humanoid robots. The research was conducted within the project which develops social humanoid robot Sara – a mobile anthropomorphic platform for researching the social behaviour of robots. There are two basic ways for the realization of humanoid wrist. The first one is based on biologically inspired structures that have variable stiffness, and the second one on low backlash mechanisms that have high stiffness. Our solution is low backlash differential mechanism that requires small actuators. Based on the kinematic-dynamic requirements, a dynamic model of the robot wrist is formed. A dynamic simulation for several hand positions was performed and the driving torques of the wrist mechanism were determined. The realized wrist has 2 DOFs and enables movements in the direction of flexion/extension 115°, ulnar/radial deviation ±45° and the combination of these two movements. It consists of a differential mechanism with three spur bevel gears, two of which are driving and identical, while the last one is the driven gear to which the robot hand is attached. Power transmission and motion from the actuator to the input links of the differential mechanism is realized with two parallel placed identical gear mechanisms. The wrist mechanism has high carrying capacity and reliability, high efficiency, a compact design and low backlash that provides high positioning accuracy and repeatability of movements, which is essential for motion control.

  4. TRIUMF cyclotron vacuum system refurbishing

    Science.gov (United States)

    Sekachev, I.

    2008-03-01

    The cyclotron at TRIUMF was commissioned to full energy in 1974. The volume of the cyclotron vacuum tank is about 100 m3 and it operates at 5×10-8 Torr pressure during beam production. The pumping is mainly based on a Phillips B-20 cryogenerator (Stirling cycle 4-cylinder engine). The cryogenerator supplies helium gas at 16 K and 70 K to cryopanels in the tank. The decreasing reliability of the B-20 and demanding maintenance requirements triggered the decision to completely overhaul or replace the cryogenerator. Replacement with the LINDE-1630 helium refrigerator was found to be the most attractive (technically and economically) option. The details of the proposal with installation of the helium refrigerator and with a continuous flow liquid nitrogen shield cooling system are presented.

  5. The development of cyclotron radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Seung Dae; Chun, K. W.; Suh, Y. S.; Lee, J. D.; Ahn, S. H. and others

    1999-03-01

    The purpose of this project is to developthe radiopharmaceuticals and automatic synthetic unit for labelled compounds, and to establish mass production system of radiopharmaceuticals. These will contribute to the early diagnosis of the disease hard to cure. The contents of this project are as follows, the development of the radiopharmaceutical for imaging of cancer, the development of automatic synthesizer for the synthesis of radio-pharmaceuticals, the development of hormone derivatives labelled with {sup 12}'3I, the development of the radiopharmaceuticals for therapy of cancer labelled with cyclotron produced radionuclides, the development of radiopharmaceuticals for therapy of cancer labelled with cyclotron produced radionuclides, the development of radiopharmaceuticals for imaging of myocardial metabolism.

  6. Method and apparatus for ion cyclotron spectrometry

    Science.gov (United States)

    Dahl, David A [Idaho Falls, ID; Scott, Jill R [Idaho Falls, ID; McJunkin, Timothy R [Idaho Falls, ID

    2010-08-17

    An ion cyclotron spectrometer may include a vacuum chamber that extends at least along a z-axis and means for producing a magnetic field within the vacuum chamber so that a magnetic field vector is generally parallel to the z-axis. The ion cyclotron spectrometer may also include means for producing a trapping electric field within the vacuum chamber that includes at least a first section that induces a first magnetron effect that increases a cyclotron frequency of an ion and at least a second section that induces a second magnetron effect that decreases the cyclotron frequency of an ion. The cyclotron frequency changes induced by the first and second magnetron effects substantially cancel one another so that an ion traversing the at least first and second sections will experience no net change in cyclotron frequency.

  7. Concurrent software system design supported by SARA at the age of one

    Energy Technology Data Exchange (ETDEWEB)

    Campos, I.M.; Estrin, G.

    A multilevel modeling method suitable for the design of concurrent hardware or software systems is presented. The methodology is requirement driven and uses tools incorporated in a programming system called SARA (Systems ARchitect's Apprentice). Both top-down refinement and bottom-up abstraction are supported. The design of an asynchronous sender-receiver illustrates the key steps in going smoothly from programing in the large to programing in the small or actual code. The same methodology can be used to design hardware systems by applying different pragmatics from those proposed for software systems. SARA consists of a set of interactive tools implemented both at UCLA and also on the MIT-Multics system. Although SARA continues in long-term development, completed design tools are accessible for experimentation by authorized users at either location via the ARPANET. 9 figures, 2 tables.

  8. ESTETIKA TARIAN SARA DOUDA DALAM MASYARAKAT ADAT LOLI (SEBUAH PENDEKATAN LINGUISTIK KEBUDAYAAN

    Directory of Open Access Journals (Sweden)

    Sulistyastuti Sutomo

    2015-01-01

    Full Text Available Not only does art   have   self-fullfillment, but  it also has axiological  benefits both socially, culturally, religiously, and economiclally.  So does Sara Douda dance.  Sara Douda aesthetics  is first contained  in its whole dance movements. In addition, it  can also be found in the whole dance equipments.  Moreover,  this dance aesthetics  may  also be contained in the verbal symbols in the speech forms  prior to the dance performance. However,  both verbal and non-verbal aesthetical forms are incorporated by the pieces of socio-cultural and  religious values in the Loli community about  their honoring their ancestors,  having social harmony, and  highly respecting each other among the community members. This study uses a cultural linguistic approach to find out and to review the aesthetics of Sara Douda dance.   Seni memang memiliki kepenuhan dalam dirinya sendiri. Tetapi ia juga sekaligus punya faedah aksiologis, baik secara sosial, kultural, religius maupun secara ekonomis. Tarian Sara Douda pun demikian. Estetika Sara Douda pertama-tama ada dalam semua gerak tariannya. Juga dalam seluruh perlengkapan tarian tersebut. Bukan itu saja, estetika tarian ini juga ada dalam simbol-simbol verbal berupa tuturan menjelang tarian. Tetapi baik bentuk-bentuk estetisasi nonverbal maupun verbal, sama-sama disatukan oleh kepingan-kepingan nilai-nilai sosio-kultural dan religius masyarakat Loli tentang penghormatan kepada leluhur, tentang harmoni sosial, dan tentang penghargaan yang tinggi terhadap satu sama lain. Penelitian ini menggunakan pendekatan linguistik kebudayaan demi menemukan dan menelaah estetika dalam tarian Sara Douda

  9. 76 FR 80982 - International Cyclotron, Inc., Hato Rey, Puerto Rico; Order Suspending Licensed Activities

    Science.gov (United States)

    2011-12-27

    ...-0292] International Cyclotron, Inc., Hato Rey, Puerto Rico; Order Suspending Licensed Activities I International Cyclotron, Inc. (International Cyclotron; Licensee) is the holder of Byproduct Materials License... International Cyclotron submitted its NRC license application related to the cyclotron, it requested...

  10. Cyclotron Line Measurements with INTEGRAL

    Science.gov (United States)

    Pottschmidt, K.; Kreykenbohm, I.; Caballero, I.; Fritz, S.; Schoenherr, G.; Kretschmar, P.; Wilms, J.; McBride, V. A.; Suchy, S.; Rothschild, R. E.

    2008-01-01

    Due to its broadband energy coverage, INTEGRAL has made important contributions to observing and interpreting cyclotron lines, which are present in the 10-100 keV range of a sample of accreting pulsars. In these systems photons with energies fulfilling the resonance condition inelastically Compton scatter off electrons quantized in the accretion column above the neutron star's magnetic pole(s). This process gives rise to the broad, absorption-like lines or 'cyclotron resonant scattering features' (CRSF). The observed lines allow to directly measure the B-fields of these sources, resulting in values of a few times 1E12G. In this overview I will present recent highlights regarding CRSF observations as well as discuss current ideas and models for the physical conditions in the accretion column. Among the former are the stability of the spectrum of Vela X-1 during giant flares in 2003, the observation of three cyclotron lines during the 2004 outburst of V0332+53, the confirmation of the fundamental line at approximately 45 keV during a 2005 normal outburst of A0535-26, and the simultaneous detection of the two lines in the dipping source 4U 1907+09 (for which also a torque reversal was detected for the first time). Through these and other observations it has become increasingly apparent that two types of observations can potentially be used to constrain the accretion column geometry: the determination of energy ratios for multiple harmonic lines (only two sources with greater than 2 lines are known), was well as the evolution of the fundamental line centroid, which, for different sources, may or may not be correlated with flux. Furthermore, first steps have been taken away from the usual phenomenological description of the lines, towards a physical approach based on self-consistent CRSF modeling. Initial applications are presented.

  11. Radiation surveillance in and around cyclotron facility

    Science.gov (United States)

    Kaur, Amandeep; Sharma, Sarika; Mittal, BR

    2012-01-01

    The cyclotron is the most widely used particle accelerator for producing medically important radio nuclides. Many medical centers in India have installed compact medical cyclotrons for on-site production of short-lived positron-emitting radio nuclides such as 18F, 13N, and 11C. A mandatory requirement for cyclotron installation is radiation control permit from Atomic Energy Regulatory Board. Cyclotron radiation survey is an integral part of the overall radiation safety in the cyclotron facility. Radiation surveillance in and around a newly installed cyclotron was performed using ionization chamber counter and Geiger Muller counter before, during and after operating the cyclotron. The readings were recorded at various locations where a high radiation field was expected. The results were recorded, tabulated and analyzed. The highest exposure level (0.93 μSv) was found at the back wall of the radiochemistry lab facing the cyclotron vault. Reason for the high exposure of 0.93 μSv/h: Synthesis of 18F-Fluoro-Deoxy-Glucose (18F-FDG) was going in the synthesis module and activity (18F) was present in the synthesis module when reading was taken. All other values were found to be below the recommended levels of exposure. PMID:24019654

  12. Developing the smallest possible medical cyclotron

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    Imagine a portable medical cyclotron operated in a conventional radioactive facility at a hospital. Imagine a nurse or technician switching it on and producing isotopes at the patient’s bedside. Sounds like science fiction? Think again.   CERN has teamed up with Spain’s national scientific research centre (CIEMAT) to develop an avant-garde cyclotron to be used for Positron Emission Tomography (PET). “We plan to make a cyclotron that doesn't need an insulated building or ‘vault’: a cyclotron small enough to fit inside a hospital lift,” explains Jose Manuel Perez, who is leading the CIEMAT/CERN collaboration. “It will be the smallest possible medical cyclotron for single patient dose production and will dramatically reduce costs for hospitals.” While PET technology has transformed imaging techniques, many of its medical benefits have remained confined to highly specialised hospitals. “Studies have foun...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-1615 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1615 ref|XP_001683626.1| formin, putative [Leishmania major] emb|CAJ04...769.1| formin, putative [Leishmania major] gb|ABQ43162.1| formin B [Leishmania major] XP_001683626.1 0.52 46% ...

  14. NCBI nr-aa BLAST: CBRC-SARA-01-0775 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0775 ref|ZP_01797490.1| multidrug resistance protein [Haemophilus influenza...e R3021] gb|EDK13267.1| multidrug resistance protein [Haemophilus influenzae 22.4-21] ZP_01797490.1 0.22 27% ...

  15. NCBI nr-aa BLAST: CBRC-SARA-01-0775 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0775 ref|ZP_01792636.1| multidrug resistance protein [Haemophilus influenza...e PittHH] gb|EDK09769.1| multidrug resistance protein [Haemophilus influenzae PittHH] ZP_01792636.1 0.22 27% ...

  16. NCBI nr-aa BLAST: CBRC-SARA-01-0775 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0775 ref|ZP_01785759.1| multidrug resistance protein [Haemophilus influenza...e 22.4-21] gb|EDJ91681.1| multidrug resistance protein [Haemophilus influenzae R3021] ZP_01785759.1 0.22 27% ...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-0775 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0775 ref|YP_248596.1| multidrug resistance protein [Haemophilus influenza...e 86-028NP] gb|AAX87936.1| multidrug resistance protein [Haemophilus influenzae 86-028NP] YP_248596.1 0.22 27% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-0775 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0775 ref|ZP_01789776.1| multidrug resistance protein [Haemophilus influenza...e PittAA] gb|EDK08502.1| multidrug resistance protein [Haemophilus influenzae PittAA] ZP_01789776.1 0.22 27% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-0775 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0775 ref|ZP_01788010.1| multidrug resistance protein [Haemophilus influenza...e 3655] gb|EDJ93712.1| multidrug resistance protein [Haemophilus influenzae 3655] ZP_01788010.1 0.22 27% ...

  20. NCBI nr-aa BLAST: CBRC-SARA-01-1485 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1485 ref|YP_001518234.1| pentapeptide repeat domain protein [Acaryochloris marina... MBIC11017] gb|ABW28917.1| pentapeptide repeat domain protein [Acaryochloris marina MBIC11017] YP_001518234.1 1.9 43% ...

  1. NCBI nr-aa BLAST: CBRC-SARA-01-0491 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0491 ref|YP_001517065.1| hypothetical protein AM1_2749 [Acaryochloris marina... MBIC11017] gb|ABW27749.1| conserved hypothetical protein [Acaryochloris marina MBIC11017] YP_001517065.1 2e-13 45% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-0899 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0899 ref|ZP_01580560.1| protein of unknown function DUF140 [Delftia ac...idovorans SPH-1] gb|EAV75499.1| protein of unknown function DUF140 [Delftia acidovorans SPH-1] ZP_01580560.1 0.001 31% ...

  3. NCBI nr-aa BLAST: CBRC-SARA-01-1656 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1656 ref|NP_001034958.1| bitter taste receptor Modo-T2R7B [Monodelphis... domestica] dbj|BAE80368.1| bitter taste receptor [Monodelphis domestica] NP_001034958.1 2e-39 43% ...

  4. NCBI nr-aa BLAST: CBRC-SARA-01-0641 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0641 ref|YP_902517.1| polysaccharide biosynthesis protein [Pelobacter propionic...us DSM 2379] gb|ABL00460.1| polysaccharide biosynthesis protein [Pelobacter propionicus DSM 2379] YP_902517.1 7.4 23% ...

  5. NCBI nr-aa BLAST: CBRC-SARA-01-0256 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0256 ref|ZP_00739965.1| Integral membrane protein [Bacillus thuringiensis serovar israel...ensis ATCC 35646] gb|EAO55770.1| Integral membrane protein [Bacillus thuringiensis serovar israelensis ATCC 35646] ZP_00739965.1 1.3 24% ...

  6. NCBI nr-aa BLAST: CBRC-SARA-01-1804 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1804 ref|ZP_00743402.1| Sensory box/GGDEF family protein [Bacillus thuringiensis serovar israel...ensis ATCC 35646] gb|EAO52327.1| Sensory box/GGDEF family protein [Bacillus thuringiensis serovar israelensis ATCC 35646] ZP_00743402.1 0.20 36% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-1811 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1811 ref|YP_001256899.1| NADH dehydrogenase subunit 1 [Reticulitermes ...flavipes] gb|ABN10430.1| NADH dehydrogenase subunit 1 [Reticulitermes flavipes] YP_001256899.1 1.5 27% ...

  8. NCBI nr-aa BLAST: CBRC-SARA-01-1811 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1811 gb|ABN10456.1| NADH dehydrogenase subunit 1 [Reticulitermes flavi...pes] gb|ABN10469.1| NADH dehydrogenase subunit 1 [Reticulitermes flavipes] ABN10456.1 0.85 28% ...

  9. NCBI nr-aa BLAST: CBRC-SARA-01-0337 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0337 ref|XP_001586881.1| predicted protein [Sclerotinia sclerotiorum 1...980] gb|EDN97385.1| predicted protein [Sclerotinia sclerotiorum 1980] XP_001586881.1 1.5 28% ...

  10. NCBI nr-aa BLAST: CBRC-SARA-01-1377 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1377 ref|XP_001588332.1| predicted protein [Sclerotinia sclerotiorum 1...980] gb|EDN94904.1| predicted protein [Sclerotinia sclerotiorum 1980] XP_001588332.1 2e-11 82% ...

  11. NCBI nr-aa BLAST: CBRC-SARA-01-0795 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0795 ref|XP_001593916.1| hypothetical protein SS1G_05344 [Sclerotinia ...sclerotiorum 1980] gb|EDO02867.1| hypothetical protein SS1G_05344 [Sclerotinia sclerotiorum 1980] XP_001593916.1 1.8 27% ...

  12. NCBI nr-aa BLAST: CBRC-SARA-01-1804 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1804 ref|XP_001594961.1| hypothetical protein SS1G_04769 [Sclerotinia ...sclerotiorum 1980] gb|EDO02293.1| hypothetical protein SS1G_04769 [Sclerotinia sclerotiorum 1980] XP_001594961.1 0.75 24% ...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-0900 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0900 ref|YP_898010.1| phosphatidylserine synthase [Francisella tularen...sis subsp. novicida U112] gb|ABK89256.1| phosphatidylserine synthase [Francisella tularensis subsp. novicida U112] YP_898010.1 3.0 27% ...

  14. NCBI nr-aa BLAST: CBRC-SARA-01-1578 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1578 ref|NP_001077100.1| cOR52N9 olfactory receptor family 52 subfamily N-like [Canis lupus... familiaris] gb|ABO36681.1| 52N9 olfactory receptor protein [Canis lupus familiaris] NP_001077100.1 1e-146 78% ...

  15. NCBI nr-aa BLAST: CBRC-SARA-01-1189 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1189 ref|ZP_01099747.1| arsenical pump membrane protein [Campylobacter... jejuni subsp. jejuni 84-25] gb|EAQ95323.1| arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni 84-25] ZP_01099747.1 0.40 27% ...

  16. NCBI nr-aa BLAST: CBRC-SARA-01-0337 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0337 ref|ZP_01099747.1| arsenical pump membrane protein [Campylobacter... jejuni subsp. jejuni 84-25] gb|EAQ95323.1| arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni 84-25] ZP_01099747.1 0.52 27% ...

  17. Indicators of induced subacute ruminal acidosis (SARA) in Danish Holstein cows

    DEFF Research Database (Denmark)

    Danscher, Anne Mette; Li, Shucong; Andersen, Pia H.

    2015-01-01

    periods included two cows on control diet and two cows on nutritional SARA challenge. The third period only included two cows on SARA challenge. Control diet was a conventional total mixed ration [45.5% dry matter (DM), 17.8% crude protein, 43.8% neutral detergent fibre, and 22.5% acid detergent fibre (DM...... basis)]. SARA challenge was conducted by substituting control diet with grain pellets (50% wheat/barley) over 3 days to reach 40% grain in the diet. Ruminal pH was measured continuously. Blood samples were collected once daily at 7 h after feeding. Samples of faeces and urine were collected at feeding......, and at 7 and 12 h after feeding. Blood samples were analysed for pCO2, pO2, pH, electrolytes, lactate, glucose, packed cell volume (PCV), and total plasma protein concentration. Milk composition, ruminal VFA, and pH of faeces and urine were measured. RESULTS: SARA was associated with decreased (P

  18. NCBI nr-aa BLAST: CBRC-SARA-01-0873 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0873 ref|ZP_01187451.1| conserved hypothetical protein [Bacillus weihenstep...hanensis KBAB4] gb|EAR73176.1| conserved hypothetical protein [Bacillus weihenstephanensis KBAB4] ZP_01187451.1 0.36 25% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-0900 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0900 ref|YP_026098.1| NADH dehydrogenase subunit 5 [Habronattus oregon...ensis] gb|AAT02495.1| NADH dehydrogenase subunit 5 [Habronattus oregonensis] YP_026098.1 0.032 22% ...

  20. NCBI nr-aa BLAST: CBRC-SARA-01-1967 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1967 ref|ZP_00370594.1| Predicted DNA repair exonuclease [Campylobacter upsaliens...is RM3195] gb|EAL53370.1| Predicted DNA repair exonuclease [Campylobacter upsaliensis RM3195] ZP_00370594.1 0.047 31% ...

  1. NCBI nr-aa BLAST: CBRC-SARA-01-1301 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1301 ref|NP_952606.1| sensory box histidine kinase/response regulator [Geobacter sulfurreduce...ns PCA] gb|AAR34929.1| sensory box histidine kinase/response regulator [Geobacter sulfurreducens PCA] NP_952606.1 6.4 31% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-1753 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1753 ref|YP_001476411.1| amino acid permease-associated region [Serratia proteamacula...ns 568] gb|ABV39283.1| amino acid permease-associated region [Serratia proteamaculans 568] YP_001476411.1 0.83 35% ...

  3. NCBI nr-aa BLAST: CBRC-SARA-01-1273 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1273 ref|YP_001111321.1| hypothetical protein GrBNV_gp54 [Gryllus bimacula...tus nudivirus] gb|ABO45387.1| unknown [Gryllus bimaculatus nudivirus] YP_001111321.1 0.001 35% ...

  4. NCBI nr-aa BLAST: CBRC-SARA-01-0430 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0430 ref|YP_001107320.1| MFS family sialic acid transporter [Saccharop...olyspora erythraea NRRL 2338] emb|CAM04395.1| MFS family sialic acid transporter [Saccharopolyspora erythraea NRRL 2338] YP_001107320.1 1.9 21% ...

  5. NCBI nr-aa BLAST: CBRC-SARA-01-1253 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1253 ref|XP_001567834.1| hypothetical protein, conserved [Leishmania brazil...iensis] emb|CAM40594.1| hypothetical protein, conserved [Leishmania braziliensis] XP_001567834.1 2.0 24% ...

  6. NCBI nr-aa BLAST: CBRC-SARA-01-0019 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0019 gb|AAP36136.1| Homo sapiens cholinergic receptor, muscarinic 1 [s...ynthetic construct] gb|AAX29286.1| cholinergic receptor muscarinic 1 [synthetic construct] gb|AAX29287.1| cholinergic receptor muscarinic 1 [synthetic construct] AAP36136.1 0.0 96% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-1323 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1323 ref|NP_001008277.1| rhodopsin [Canis lupus familiaris] ref|XP_855...608.1| PREDICTED: rhodopsin [Canis familiaris] emb|CAA70209.1| unnamed protein product [Canis familiaris] NP_001008277.1 2e-62 94% ...

  8. NCBI nr-aa BLAST: CBRC-SARA-01-0641 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0641 ref|YP_626525.1| NADH dehydrogenase subunit 1 [Schistosoma haematobium] gb|AAZ57313.1| NADH dehydrogenase subunit 1 [Schistosoma haematobium] YP_626525.1 7.4 27% ...

  9. NCBI nr-aa BLAST: CBRC-SARA-01-1635 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1635 ref|NP_001087219.1| patched domain containing 1 [Mus musculus] emb|CAM15552.1| patch...ed domain containing 1 [Mus musculus] emb|CAM20498.1| patched domain containing 1 [Mus musculus] NP_001087219.1 0.0 94% ...

  10. NCBI nr-aa BLAST: CBRC-SARA-01-1169 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1169 ref|XP_001173201.1| PREDICTED: dispatched A isoform 3 [Pan troglo...dytes] ref|XP_514220.2| PREDICTED: dispatched A isoform 4 [Pan troglodytes] XP_001173201.1 0.0 96% ...

  11. NCBI nr-aa BLAST: CBRC-SARA-01-1169 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1169 ref|XP_001099799.1| PREDICTED: similar to dispatched A isoform 2 ...[Macaca mulatta] ref|XP_001099904.1| PREDICTED: similar to dispatched A isoform 3 [Macaca mulatta] XP_001099799.1 0.0 96% ...

  12. NCBI nr-aa BLAST: CBRC-SARA-01-0489 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0489 ref|ZP_01585795.1| Polyphosphate kinase [Dinoroseobacter shibae D...FL 12] gb|ABV92485.1| Polyphosphate kinase [Dinoroseobacter shibae DFL 12] ZP_01585795.1 1.8 28% ...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-0832 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0832 ref|ZP_01585795.1| Polyphosphate kinase [Dinoroseobacter shibae D...FL 12] gb|ABV92485.1| Polyphosphate kinase [Dinoroseobacter shibae DFL 12] ZP_01585795.1 1.8 28% ...

  14. NCBI nr-aa BLAST: CBRC-SARA-01-1549 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1549 ref|NP_937906.1| NADH dehydrogenase subunit 2 [Strongyloides stercoral...is] emb|CAD90566.1| NADH dehydrogenase subunit 2 [Strongyloides stercoralis] NP_937906.1 1.2 38% ...

  15. NCBI nr-aa BLAST: CBRC-SARA-01-1847 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1847 ref|NP_937902.1| NADH dehydrogenase subunit 5 [Strongyloides stercoral...is] emb|CAD90562.1| NADH dehydrogenase subunit 5 [Strongyloides stercoralis] NP_937902.1 3e-16 32% ...

  16. NCBI nr-aa BLAST: CBRC-SARA-01-0175 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0175 ref|YP_880812.1| AMP-binding enzyme, putative [Mycobacterium avium... 104] gb|ABK67935.1| AMP-binding enzyme, putative [Mycobacterium avium 104] YP_880812.1 2.4 32% ...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-1253 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1253 ref|YP_264377.1| hypothetical protein Psyc_1092 [Psychrobacter arctic...us 273-4] gb|AAZ18943.1| conserved hypothetical protein [Psychrobacter arcticus 273-4] YP_264377.1 1.2 25% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-0991 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0991 ref|YP_873218.1| chitinase. Glycosyl Hydrolase family 18. [Acidothermus... cellulolyticus 11B] gb|ABK53232.1| chitinase. Glycosyl Hydrolase family 18. [Acidothermus cellulolyticus 11B] YP_873218.1 9.3 29% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-1766 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1766 ref|NP_001029087.1| opioid receptor, mu 1 [Pan troglodytes] sp|Q5...IS39|OPRM_PANTR Mu-type opioid receptor (MOR-1) gb|AAV74327.1| opioid receptor MU-1 [Pan troglodytes] NP_001029087.1 0.0 90% ...

  20. NCBI nr-aa BLAST: CBRC-SARA-01-0378 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0378 ref|YP_001302962.1| putative flippase [Parabacteroides distasonis... ATCC 8503] gb|ABR43340.1| putative flippase [Parabacteroides distasonis ATCC 8503] YP_001302962.1 5.1 26% ...

  1. NCBI nr-aa BLAST: CBRC-SARA-01-1755 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1755 ref|NP_001034954.1| bitter taste receptor Modo-T2R3A [Monodelphis domestic...a] dbj|BAE80360.1| bitter taste receptor [Monodelphis domestica] NP_001034954.1 3e-38 36% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-0389 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0389 ref|NP_001034959.1| bitter taste receptor Modo-T2R41 [Monodelphis domestic...a] dbj|BAE80381.1| bitter taste receptor [Monodelphis domestica] NP_001034959.1 1e-101 60% ...

  3. NCBI nr-aa BLAST: CBRC-SARA-01-1755 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1755 ref|NP_001034947.1| bitter taste receptor Modo-T2R25 [Monodelphis domestic...a] dbj|BAE80373.1| bitter taste receptor [Monodelphis domestica] NP_001034947.1 1e-40 35% ...

  4. NCBI nr-aa BLAST: CBRC-SARA-01-1746 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1746 ref|NP_001100989.1| non imprinted in Prader-Willi/Angelman syndro...me 1 homolog [Rattus norvegicus] gb|EDL86455.1| non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human) (predicted) [Rattus norvegicus] NP_001100989.1 1e-113 80% ...

  5. NCBI nr-aa BLAST: CBRC-SARA-01-0854 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available eptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism), isoform CRA_c [Homo sapiens] EAW79490.1 0.0 90% ... ...mia 1, severe neonatal hyperparathyroidism), isoform CRA_a [Homo sapiens] gb|EAW79492.1| calcium-sensing rec...CBRC-SARA-01-0854 gb|EAW79490.1| calcium-sensing receptor (hypocalciuric hypercalce

  6. NCBI nr-aa BLAST: CBRC-SARA-01-1651 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1651 ref|YP_133655.1| hypothetical efflux family protein [Photobacterium... profundum SS9] emb|CAG23855.1| hypothetical efflux family protein [Photobacterium profundum SS9] YP_133655.1 2.6 24% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-1986 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1986 ref|NP_223335.1| INTEGRASE-RECOMBINASE PROTEIN (XERCD FAMILY) [Helicobacter... pylori J99] gb|AAD06197.1| INTEGRASE-RECOMBINASE PROTEIN (XERCD FAMILY) [Helicobacter pylori J99] NP_223335.1 5.2 32% ...

  8. NCBI nr-aa BLAST: CBRC-SARA-01-0430 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0430 ref|NP_928319.1| hypothetical protein plu0985 [Photorhabdus lumines...cens subsp. laumondii TTO1] emb|CAE13280.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1] NP_928319.1 1.9 22% ...

  9. NCBI nr-aa BLAST: CBRC-SARA-01-1521 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1521 ref|NP_928273.1| hypothetical protein plu0937 [Photorhabdus lumines...cens subsp. laumondii TTO1] emb|CAE13232.1| unnamed protein product [Photorhabdus luminescens subsp. laumondii TTO1] NP_928273.1 1.2 25% ...

  10. NCBI nr-aa BLAST: CBRC-SARA-01-0771 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0771 ref|NP_001033642.1| progestin and adipoQ receptor family member V...II [Bos taurus] gb|AAI11285.1| Progestin and adipoQ receptor family member VII [Bos taurus] NP_001033642.1 1e-180 87% ...

  11. NCBI nr-aa BLAST: CBRC-SARA-01-0771 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0771 ref|NP_001029253.1| progestin and adipoQ receptor family member V...II [Rattus norvegicus] gb|AAY67652.1| progestin membrane receptor alpha [Rattus norvegicus] NP_001029253.1 1e-167 82% ...

  12. NCBI nr-aa BLAST: CBRC-SARA-01-1648 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1648 ref|NP_694727.1| histamine H4 receptor [Mus musculus] gb|AAK97380.1|AF358859_1 histamine... H4 receptor [Mus musculus] gb|EDL01579.1| histamine H4 receptor [Mus musculus] NP_694727.1 1e-129 61% ...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-0420 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0420 ref|YP_378724.1| sodium/bile acid symporter family protein [Chlorobi...um chlorochromatii CaD3] gb|ABB27681.1| sodium/bile acid symporter family protein [Chlorobium chlorochromatii CaD3] YP_378724.1 0.15 27% ...

  14. NCBI nr-aa BLAST: CBRC-SARA-01-1804 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1804 ref|NP_965427.1| hypothetical protein LJ1621 [Lactobacillus johns...onii NCC 533] gb|AAS09393.1| hypothetical protein LJ_1621 [Lactobacillus johnsonii NCC 533] NP_965427.1 0.12 24% ...

  15. NCBI nr-aa BLAST: CBRC-SARA-01-0459 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0459 ref|YP_001297164.1| hypothetical protein FP2308 [Flavobacterium psych...rophilum JIP02/86] emb|CAL44363.1| Protein of unknown function [Flavobacterium psychrophilum JIP02/86] YP_001297164.1 7.3 30% ...

  16. NCBI nr-aa BLAST: CBRC-SARA-01-0488 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0488 ref|YP_064024.1| sulfate permease (SulP) [Desulfotalea psychrophi...la LSv54] emb|CAG35017.1| probable sulfate permease (SulP) [Desulfotalea psychrophila LSv54] YP_064024.1 6.1 37% ...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-0200 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0200 ref|NP_036900.1| dopamine receptor D5 [Rattus norvegicus] sp|P25115|DRD5_RAT D(1B) dopamin...e receptor (D(5) dopamine receptor) gb|AAA41072.1| dopamine D1B receptor NP_036900.1 3e-47 59% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-0834 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0834 ref|NP_036900.1| dopamine receptor D5 [Rattus norvegicus] sp|P25115|DRD5_RAT D(1B) dopamin...e receptor (D(5) dopamine receptor) gb|AAA41072.1| dopamine D1B receptor NP_036900.1 3e-47 59% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-0522 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0522 ref|YP_001499570.1| Peptidyl-tRNA hydrolase [Rickettsia massiliae... MTU5] gb|ABV85023.1| Peptidyl-tRNA hydrolase [Rickettsia massiliae MTU5] YP_001499570.1 4.7 36% ...

  20. NCBI nr-aa BLAST: CBRC-SARA-01-0685 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0685 ref|ZP_01514139.1| hypothetical protein CaggDRAFT_2618 [Chloroflexus... aggregans DSM 9485] gb|EAV12137.1| hypothetical protein CaggDRAFT_2618 [Chloroflexus aggregans DSM 9485] ZP_01514139.1 2.9 25% ...

  1. NCBI nr-aa BLAST: CBRC-SARA-01-2026 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-2026 ref|YP_008277.1| hypothetical protein pc1278 [Candidatus Protochlamydia... amoebophila UWE25] emb|CAF24002.1| conserved hypothetical protein [Candidatus Protochlamydia amoebophila UWE25] YP_008277.1 0.89 28% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-0159 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0159 ref|YP_008619.1| hypothetical protein pc1620 [Candidatus Protochlamydia... amoebophila UWE25] emb|CAF24344.1| conserved hypothetical protein [Candidatus Protochlamydia amoebophila UWE25] YP_008619.1 7.8 27% ...

  3. NCBI nr-aa BLAST: CBRC-SARA-01-2026 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-2026 ref|YP_008281.1| hypothetical protein pc1282 [Candidatus Protochlamydia... amoebophila UWE25] emb|CAF24006.1| conserved hypothetical protein [Candidatus Protochlamydia amoebophila UWE25] YP_008281.1 3.4 25% ...

  4. NCBI nr-aa BLAST: CBRC-SARA-01-0256 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0256 ref|YP_028006.1| peptidase, M23/M37 family [Bacillus anthracis str. Sterne...] gb|AAT54057.1| peptidase, M23/M37 family [Bacillus anthracis str. Sterne] YP_028006.1 0.96 31% ...

  5. NCBI nr-aa BLAST: CBRC-SARA-01-0377 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0377 ref|YP_028006.1| peptidase, M23/M37 family [Bacillus anthracis str. Sterne...] gb|AAT54057.1| peptidase, M23/M37 family [Bacillus anthracis str. Sterne] YP_028006.1 0.001 28% ...

  6. NCBI nr-aa BLAST: CBRC-SARA-01-1688 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1688 emb|CAH72617.1| chromosome 10 open reading frame 18 [Homo sapiens...] emb|CAI13368.1| chromosome 10 open reading frame 18 [Homo sapiens] CAH72617.1 1e-103 49% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-1683 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1683 ref|YP_776459.1| Haemagluttinin domain protein [Burkholderia cepa...cia AMMD] gb|ABI90125.1| Haemagluttinin domain protein [Burkholderia ambifaria AMMD] YP_776459.1 0.16 28% ...

  8. NCBI nr-aa BLAST: CBRC-SARA-01-0430 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0430 ref|NP_878187.1| NADH dehydrogenase subunit 1 [Fejervarya limnoch...aris] gb|AAO12107.1| NADH dehydrogenase subunit 1 [Fejervarya limnocharis] NP_878187.1 2.5 29% ...

  9. NCBI nr-aa BLAST: CBRC-SARA-01-0383 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0383 ref|XP_001557940.1| predicted protein [Botryotinia fuckeliana B05....10] gb|EDN20132.1| predicted protein [Botryotinia fuckeliana B05.10] XP_001557940.1 4.0 31% ...

  10. NCBI nr-aa BLAST: CBRC-SARA-01-0626 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0626 ref|XP_001275412.1| PHD finger and SET domain protein, putative [Aspergillus clava...tus NRRL 1] gb|EAW13986.1| PHD finger and SET domain protein, putative [Aspergillus clavatus NRRL 1] XP_001275412.1 5.4 25% ...

  11. NCBI nr-aa BLAST: CBRC-SARA-01-1651 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1651 ref|NP_923236.1| cobalt ABC transporter permease protein CbiQ homolog [Gloeobacter viola...ceus PCC 7421] dbj|BAC88231.1| gll0290 [Gloeobacter violaceus PCC 7421] NP_923236.1 0.52 28% ...

  12. NCBI nr-aa BLAST: CBRC-SARA-01-0491 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0491 ref|NP_925838.1| hypothetical protein gll2892 [Gloeobacter violac...eus PCC 7421] dbj|BAC90833.1| gll2892 [Gloeobacter violaceus PCC 7421] NP_925838.1 3e-16 37% ...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-1668 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1668 ref|XP_001464626.1| hypothetical protein LinJ16.1450 [Leishmania infant...um JPCM5] emb|CAM67023.1| hypothetical protein [Leishmania infantum] XP_001464626.1 3.6 36% ...

  14. NCBI nr-aa BLAST: CBRC-SARA-01-1999 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1999 ref|YP_126627.1| hypothetical protein lpl1277 [Legionella pneumop...hila str. Lens] emb|CAH15517.1| hypothetical protein [Legionella pneumophila str. Lens] YP_126627.1 0.38 21% ...

  15. NCBI nr-aa BLAST: CBRC-SARA-01-1309 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1309 ref|YP_001125845.1| hypothetical protein GTNG_1736 [Geobacillus t...hermodenitrificans NG80-2] gb|ABO67100.1| Conserved hypothetical protein [Geobacillus thermodenitrificans NG80-2] YP_001125845.1 0.47 23% ...

  16. NCBI nr-aa BLAST: CBRC-SARA-01-1960 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1960 ref|YP_687145.1| hypothetical protein RRC34 [uncultured methanoge...nic archaeon RC-I] emb|CAJ37819.1| hypothetical protein [uncultured methanogenic archaeon RC-I] YP_687145.1 9e-19 40% ...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-1560 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1560 ref|YP_984227.1| filamentous haemagglutinin family outer membrane... protein [Polaromonas naphthalenivorans CJ2] gb|ABM39306.1| filamentous haemagglutinin family outer membrane protein [Polaromonas naphthalenivorans CJ2] YP_984227.1 2.9 30% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-1922 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1922 ref|NP_001003037.1| melanin-concentrating hormone receptor 2 [Can...is lupus familiaris] gb|AAM51852.1| melanin-concentrating hormone receptor subtype 2 [Canis familiaris] NP_001003037.1 1e-126 73% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-1922 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1922 ref|NP_001038074.1| putative melanin concentrating hormone recept...or 2 [Sus scrofa] emb|CAJ55683.1| putative melanin concentrating hormone receptor 2 [Sus scrofa] NP_001038074.1 1e-129 73% ...

  20. NCBI nr-aa BLAST: CBRC-SARA-01-0883 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available stance-K receptor (SKR) (Neurokinin A receptor) (NK-2 receptor) (NK-2R) (Tachykinin...CBRC-SARA-01-0883 ref|NP_001075800.1| tachykinin receptor 2 [Oryctolagus cuniculus] sp|P79218|NK2R_RABIT Sub

  1. NCBI nr-aa BLAST: CBRC-SARA-01-1309 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1309 ref|YP_033365.1| hypothetical protein BH05300 [Bartonella hensela...e str. Houston-1] emb|CAF27338.1| hypothetical protein [Bartonella henselae str. Houston-1] YP_033365.1 0.47 19% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-1488 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1488 ref|ZP_01187451.1| conserved hypothetical protein [Bacillus weihens...tephanensis KBAB4] gb|EAR73176.1| conserved hypothetical protein [Bacillus weihenstephanensis KBAB4] ZP_01187451.1 0.78 25% ...

  3. Reading, Laterality, and the Brain: Early Contributions on Reading Disabilities by Sara S. Sparrow

    Science.gov (United States)

    Fletcher, Jack M.; Morris, Robin D.

    2014-01-01

    Although best known for work with children and adults with intellectual disabilities and autism spectrum disorders, training in speech pathology and a doctorate in clinical psychology and neuropsychology was the foundation for Sara Sparrow's long-term interest in reading disabilities. Her first papers were on dyslexia and laterality, and the…

  4. Pollution of liquid argon after neutron irradiation measured at SARA: summary of raw data

    CERN Document Server

    Andrieux, M L; de Saintignon, P; Ferrari, A; Hostachy, J Y; Martin, P; Wielers, M; Belymam, A; Hoummada, A; Merkel, B; Puzo, P M; Sauvage, D

    1998-01-01

    The SARA fast neutron facility has been used to irradiate various pieces of materials due to be used in the ATLAS electromagnetic calorimeter, immersed in a liquid argon cryostat. The subsequent pollution was measured. The raw data have been summarized in this paper.

  5. NCBI nr-aa BLAST: CBRC-SARA-01-1099 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1099 ref|YP_001337495.1| hypothetical protein KPN_03841 [Klebsiella pneumoniae subsp. pneumonia...e MGH 78578] gb|ABR79228.1| hypothetical protein KPN_03841 [Klebsiella pneumoniae subsp. pneumoniae MGH 78578] YP_001337495.1 0.93 29% ...

  6. NCBI nr-aa BLAST: CBRC-SARA-01-0415 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0415 ref|YP_547770.1| NADH dehydrogenase (quinone) [Polaromonas sp. JS...666] gb|ABE42872.1| NADH dehydrogenase (quinone) [Polaromonas sp. JS666] YP_547770.1 4.6 26% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-1868 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1868 ref|NP_067356.2| prokineticin receptor 1 [Mus musculus] gb|AAH59003.1| Prokinetic...2080.1| unnamed protein product [Mus musculus] gb|EDK99210.1| prokineticin receptor 1 [Mus musculus] NP_067356.2 2e-55 77% ...

  8. NCBI nr-aa BLAST: CBRC-SARA-01-1386 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1386 ref|XP_001165973.1| PREDICTED: prokineticin receptor 2 isoform 1 ...[Pan troglodytes] ref|XP_001166012.1| PREDICTED: prokineticin receptor 2 isoform 2 [Pan troglodytes] XP_001165973.1 1e-115 91% ...

  9. NCBI nr-aa BLAST: CBRC-SARA-01-0832 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0832 ref|ZP_01035526.1| exopolysaccharide biosynthesis domain protein [Rose...ovarius sp. 217] gb|EAQ25691.1| exopolysaccharide biosynthesis domain protein [Roseovarius sp. 217] ZP_01035526.1 1.0 26% ...

  10. NCBI nr-aa BLAST: CBRC-SARA-01-0489 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0489 ref|ZP_01035526.1| exopolysaccharide biosynthesis domain protein [Rose...ovarius sp. 217] gb|EAQ25691.1| exopolysaccharide biosynthesis domain protein [Roseovarius sp. 217] ZP_01035526.1 1.0 26% ...

  11. NCBI nr-aa BLAST: CBRC-SARA-01-0759 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0759 ref|NP_001068648.1| transmembrane protein 34 [Bos taurus] sp|Q17QL9|TMM34_BOVIN Transme...mbrane protein 34 gb|AAI18283.1| Transmembrane protein 34 [Bos taurus] NP_001068648.1 1e-156 63% ...

  12. NCBI nr-aa BLAST: CBRC-SARA-01-1999 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1999 ref|YP_095353.1| drug resistance transporter, Bcr/CflA [Legionella pneumophila... subsp. pneumophila str. Philadelphia 1] gb|AAU27406.1| drug resistance transporter, Bcr/CflA [Legionella pneumophila... subsp. pneumophila str. Philadelphia 1] YP_095353.1 0.29 21% ...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-0388 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0388 ref|YP_456746.1| phosphatidate cytidylyltransferase [Aster yellows witches...'-broom phytoplasma AYWB] gb|ABC65667.1| phosphatidate cytidylyltransferase [Aster yellows witches'-broom phytoplasma AYWB] YP_456746.1 2e-06 35% ...

  14. NCBI nr-aa BLAST: CBRC-SARA-01-1189 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1189 ref|ZP_01068559.1| arsenical pump membrane protein [Campylobacter... jejuni subsp. jejuni CF93-6] gb|EAQ56421.1| arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni CF93-6] ZP_01068559.1 0.53 28% ...

  15. NCBI nr-aa BLAST: CBRC-SARA-01-1189 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1189 ref|ZP_01069237.1| arsenical pump membrane protein [Campylobacter... jejuni subsp. jejuni 260.94] gb|EAQ59437.1| arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni 260.94] ZP_01069237.1 0.53 28% ...

  16. NCBI nr-aa BLAST: CBRC-SARA-01-0337 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0337 ref|ZP_01069237.1| arsenical pump membrane protein [Campylobacter... jejuni subsp. jejuni 260.94] gb|EAQ59437.1| arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni 260.94] ZP_01069237.1 0.67 27% ...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-0337 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0337 ref|ZP_01068559.1| arsenical pump membrane protein [Campylobacter... jejuni subsp. jejuni CF93-6] gb|EAQ56421.1| arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni CF93-6] ZP_01068559.1 0.67 27% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-0900 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0900 ref|ZP_01809404.1| NADH dehydrogenase I chain M [Campylobacter je...juni subsp. jejuni CG8486] gb|EDK22817.1| NADH dehydrogenase I chain M [Campylobacter jejuni subsp. jejuni CG8486] ZP_01809404.1 4.0 30% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-0337 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0337 ref|YP_001482707.1| putative arsenical pump membrane protein [Cam...pylobacter jejuni subsp. jejuni 81116] gb|ABV52730.1| putative arsenical pump membrane protein [Campylobacter jejuni subsp. jejuni 81116] YP_001482707.1 0.67 27% ...

  20. NCBI nr-aa BLAST: CBRC-SARA-01-1697 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1697 ref|YP_913162.1| NADH dehydrogenase subunit 5 [Romanomermis culic...ivorax] gb|ABL11589.1| NADH dehydrogenase subunit 5 [Romanomermis culicivorax] YP_913162.1 0.62 35% ...

  1. NCBI nr-aa BLAST: CBRC-SARA-01-0522 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0522 ref|YP_913161.1| ATP synthase F0 subunit 6 [Romanomermis culicivo...rax] gb|ABL11588.1| ATP synthase F0 subunit 6 [Romanomermis culicivorax] YP_913161.1 0.33 24% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-1766 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1766 ref|NP_776833.1| opioid receptor, mu 1 [Bos taurus] sp|P79350|OPRM_BOVIN Mu-type opio...id receptor (MOR-1) gb|AAB49477.2| mu opioid receptor [Bos taurus] NP_776833.1 0.0 91% ...

  3. Konflik SARA pada Pilkada DKI Jakarta di Grup WhatsApp dengan Anggota Multikultural

    Directory of Open Access Journals (Sweden)

    Tiara Kharisma

    2017-12-01

    Full Text Available Keanekaragaman SARA di Indonesia melahirkan masyarakat multikultural. Dalam kehidupannya, komunikasi antarbudaya tidak dapat dihindarkan. Salah satu medium dalam melakukan komunikasi antarbudaya adalah media sosial. Pada masyarakat multikultural isu SARA menjadi faktor utama penyebab terjadinya konflik. Di Pilkada DKI Jakarta 2017, isu SARA di grup WhatsApp marak menyebar termasuk anggota grup yang heterogen. Penelitian ini bertujuan untuk mengetahui pengelolaan konflik isu SARA pada Pilkada DKI Jakarta 2017 di grup WhatsApp dengan anggota multikultural. Penelitian ini menggunakan pendekatan kualitatif dengan teknik pengumpulan data melalui wawancara dan studi literatur. Dalam membahas penelitian ini, peneliti menggunakan kerangka teori manajemen konflik dari Martin, J. N. dan Nakayama. Hasil penelitian menunjukkan bahwa konflik terjadi karena ada anggota grup menyampaikan pesan bukan berangkat dari kesamaan anggota grup, yakni kepentingan dan tujuan awal dibentuknya grup. Pesan disebarkan dengan menganggap wujud pembelaan terhadap suatu agama. Ketika konflik terjadi, strategi pengelolaan konflik yang diterapkan adalah strategi mengompromikan (compromising dan menghindar (avoiding. Dalam grup terdapat anggota yang berperan sebagai cultural brokers.

  4. NCBI nr-aa BLAST: CBRC-SARA-01-1697 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1697 ref|YP_698029.1| hypothetical protein CPR_0703 [Clostridium perfr...ingens SM101] gb|ABG86207.1| hypothetical protein CPR_0703 [Clostridium perfringens SM101] YP_698029.1 0.62 26% ...

  5. NCBI nr-aa BLAST: CBRC-SARA-01-1986 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1986 ref|YP_001391163.1| hypothetical protein CLI_1905 [Clostridium bo...tulinum F str. Langeland] gb|ABS40017.1| hypothetical protein CLI_1905 [Clostridium botulinum F str. Langeland] YP_001391163.1 3.1 34% ...

  6. NCBI nr-aa BLAST: CBRC-SARA-01-0175 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0175 ref|NP_603288.1| hypothetical protein FN0384 [Fusobacterium nucle...atum subsp. nucleatum ATCC 25586] gb|AAL94587.1| Hypothetical protein [Fusobacterium nucleatum subsp. nucleatum ATCC 25586] NP_603288.1 9.0 32% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-0415 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0415 ref|YP_904283.1| ammonium-transport integral membrane protein, Amt_1 [Mycobacterium ulcera...ns Agy99] gb|ABL02812.1| ammonium-transport integral membrane protein, Amt_1 [Mycobacterium ulcerans Agy99] YP_904283.1 6.1 29% ...

  8. Cyclotrons: From Science to Human Health

    Science.gov (United States)

    Craddock, Michael

    2011-04-01

    Lawrence's invention of the cyclotron, whose 80th anniversary we have just celebrated, not only revolutionized nuclear physics, but proved the starting point for a whole variety of recirculating accelerators, from the smallest microtron to the largest synchrotron, that have had an enormous impact in almost every branch of science and in several areas of medicine and industry. Cyclotrons themselves have proved remarkably adaptable, incorporating a variety of new ideas and technologies over the years: frequency modulation, edge focusing, AG focusing, separate magnet sectors, axial and azimuthal injection, ring geometries, stripping extraction, superconducting magnets and rf...... Even FFAGs, those most complex members of the cyclotron (fixed-magnetic-field) family, are making a comeback. Currently there are more than 50 medium or large cyclotrons around the world devoted to research. These provide intense primary beams of protons or stable ions, and correspondingly intense secondary beams of neutrons, pions, muons and radioactive ions, for experiments in nuclear, particle and condensed-matter physics, and in the materials and life sciences. Far outnumbering these, however, are the 800 or so small and medium cyclotrons used to produce radioisotopes for medical and other purposes. In addition, a rapidly growing number of 230-MeV proton cyclotrons are being built for cancer therapy -12 brought into operation since 1998 and as many more in the works. Altogether, cyclotrons are flourishing!

  9. Method and apparatuses for ion cyclotron spectrometry

    Science.gov (United States)

    Dahl, David A [Idaho Falls, ID; Scott, Jill R [Idaho Falls, ID; McJunkin, Timothy R [Idaho Falls, ID

    2012-03-06

    An ion cyclotron spectrometer may include a vacuum chamber that extends at least along a z-axis and means for producing a magnetic field within the vacuum chamber so that a magnetic field vector is generally parallel to the z-axis. The ion cyclotron spectrometer may also include means for producing a trapping electric field within the vacuum chamber. The trapping electric field may comprise a field potential that, when taken in cross-section along the z-axis, includes at least one section that is concave down and at least one section that is concave up so that ions traversing the field potential experience a net magnetron effect on a cyclotron frequency of the ions that is substantially equal to zero. Other apparatuses and a method for performing ion cyclotron spectrometry are also disclosed herein.

  10. 10 GHz ECRIS for Warsaw Cyclotron

    CERN Document Server

    Sudlitz, K

    1999-01-01

    Cusp type, 10 GHz ECRIS has been built and tested earlier. For obtaining intensive beams, more relevant for cyclotron, cusp geometry has been replaced by hexapole. Discharge chamber (stainless steel, 50 mm diameter, 250 mm long) is an extension of a coaxial line, feeding RF (9,6 GHz, up to 200 W) to the plasma. The NdFeB hexapole (0,52 T on the surface) has been used. The axial magnetic field is created by water cooled coils. The axial injection line dedicated to K160 isochronous heavy ion cyclotron has been constructed. The line consists of Glaser lenses, double focusing magnet, solenoid and mirror type inflector. The system provides sufficient transmission of the beam from ECR ion source to the firsts orbits of the cyclotron for m/q ranging from 7 to 2. After successful initial tests which were done in July 1997 the ECRIS serves as an external source for Warsaw Cyclotron.

  11. Cyclotron axial ion-beam-buncher system

    Energy Technology Data Exchange (ETDEWEB)

    Hamm, R.W.; Swenson, D.A.; Wangler, T.P.

    1982-02-11

    Adiabatic ion bunching is achieved in a cyclotron axial ion injection system through the incorporation of a radio frequency quadrupole system, which receives ions from an external ion source via an accelerate-decelerate system and a focusing einzel lens system, and which adiabatically bunches and then injects the ions into the median plane of a cyclotron via an electrostatic quadrupole system and an inflection mirror.

  12. Building 211 cyclotron characterization survey report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-30

    The Building 211 Cyclotron Characterization Survey includes an assessment of the radioactive and chemical inventory of materials stored within the facility; an evaluation of the relative distribution of accelerator-produced activation products within various cyclotron components and adjacent structures; measurement of the radiation fields throughout the facility; measurement and assessment of internal and external radioactive surface contamination on various equipment, facility structures, and air-handling systems; and an assessment of lead (Pb) paint and asbestos hazards within the facility.

  13. Identification of Differentially Expressed Proteins in Liver in Response to Subacute Ruminal Acidosis (SARA Induced by High-concentrate Diet

    Directory of Open Access Journals (Sweden)

    X. Y. Jiang

    2014-08-01

    Full Text Available The aim of this study was to evaluate protein expression patterns of liver in response to subacute ruminal acidosis (SARA induced by high-concentrate diet. Sixteen healthy mid-lactating goats were randomly divided into 2 groups and fed either a high-forage (HF diet or a high-concentrate (HC diet. The HC diet was expected to induce SARA. After ensuring the occurrence of SARA, liver samples were collected. Proteome analysis with differential in gel electrophoresis technology revealed that, 15 proteins were significantly modulated in liver in a comparison between HF and HC-fed goats. These proteins were found mainly associated with metabolism and energy transfer after identified by matrix-assisted laser desorption ionization/time of flight. The results indicated that glucose, lipid and protein catabolism could be enhanced when SARA occurred. It prompted that glucose, lipid and amine acid in the liver mainly participated in oxidation and energy supply when SARA occurred, which possibly consumed more precursors involved in milk protein and milk fat synthesis. These results suggest new candidate proteins that may contribute to a better understanding of the mechanisms that mediate liver adaptation to SARA.

  14. Reading, laterality, and the brain: early contributions on reading disabilities by Sara S. Sparrow.

    Science.gov (United States)

    Fletcher, Jack M; Morris, Robin D

    2014-02-01

    Although best known for work with children and adults with intellectual disabilities and autism spectrum disorders, training in speech pathology and a doctorate in clinical psychology and neuropsychology was the foundation for Sara Sparrow's long-term interest in reading disabilities. Her first papers were on dyslexia and laterality, and the maturational lag theory of developmental dyslexia proposed with Paul Satz, her mentor. The research program that emerged from this work had a wide impact on early neuropsychological models of reading disabilities. Although Sara went on to research focused on children with other developmental disabilities after she moved to Yale University, this initial research influenced her career- long interests in assessment, developmental models of disabilities, and early screening methods.

  15. Serum acute phase proteins in cows with SARA (Subacute Ruminal Acidosis suspect

    Directory of Open Access Journals (Sweden)

    C. Cannizzo

    2012-02-01

    Full Text Available The aim of this study was to evaluate the variations of Acute Phase Proteins (APPs and other blood constituents during the onset of the sub-acute ruminal acidosis (SARA pathological status. A total of 108 cows from 12 dairy herds were randomly selected and divided into three Groups of 36 animals each. All animals were subjected to a rumenocentesis. Group A was composed by subjects with a rumen pH>5.8, Group B was composed by subjects with a rumen pH ≤5.5≤5.8 and Group C was composed by subjects with a rumen pH<5.5. Blood samples were collected by jugular venipuncture and Haptoglobin (Hp, Serum Amyloid A (SAA, Total Proteins, Albumin and White Blood Cells (WBC were determined. One-way ANOVA showed a statistical significance on Rumen pH, Hp, SAA. SARA seems not stimulate the APPs production from liver.

  16. NCBI nr-aa BLAST: CBRC-SARA-01-1792 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1792 ref|XP_001203256.1| PREDICTED: similar to Strong similarity to ex...tensin-like protein gb|Z34465 from Zea mays. [Strongylocentrotus purpuratus] ref|XP_001187833.1| PREDICTED: similar to Strong... similarity to extensin-like protein gb|Z34465 from Zea mays. [Strongylocentrotus purpuratus] XP_001203256.1 8e-13 32% ...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-1228 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1228 ref|XP_001203256.1| PREDICTED: similar to Strong similarity to ex...tensin-like protein gb|Z34465 from Zea mays. [Strongylocentrotus purpuratus] ref|XP_001187833.1| PREDICTED: similar to Strong... similarity to extensin-like protein gb|Z34465 from Zea mays. [Strongylocentrotus purpuratus] XP_001203256.1 1e-16 40% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-1746 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1746 ref|NP_653200.2| non-imprinted in Prader-Willi/Angelman syndrome ...1 [Homo sapiens] sp|Q7RTP0|NIPA1_HUMAN Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 tpg|...DAA01477.1| TPA_exp: non-imprinted in Prader-Willi/Angelman syndrome 1 [Homo sapiens] NP_653200.2 1e-113 81% ...

  19. NCBI nr-aa BLAST: CBRC-SARA-01-0466 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0466 dbj|BAF32759.1| taste receptor, type 1, member 3 [Sus scrofa dome...stica] dbj|BAF32761.1| taste receptor, type 1, member 3 [Sus scrofa domestica] dbj|BAF32762.1| taste recepto...r, type 1, member 3 [Sus scrofa domestica] dbj|BAF32763.1| taste receptor, type 1, member 3 [Sus scrofa domestica] BAF32759.1 3e-32 71% ...

  20. Reading, Laterality, and the Brain: Early Contributions on Reading Disabilities by Sara S. Sparrow

    OpenAIRE

    Fletcher, Jack M.; Morris, Robin D.

    2014-01-01

    Although best known for work with children and adults with intellectual disabilities and autism spectrum disorders, training in speech pathology and a doctorate in clinical psychology and neuropsychology was the foundation for Sara Sparrow’s long-term interest in reading disabilities. Her first papers were on dyslexia and laterality, and the maturational lag theory of developmental dyslexia proposed with Paul Satz, her mentor. The research program that emerged from this work had a wide impact...

  1. NCBI nr-aa BLAST: CBRC-SARA-01-1750 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1750 ref|NP_776992.1| opsin 1 (cone pigments), short-wave-sensitive (c...olor blindness, tritan) [Bos taurus] sp|P51490|OPSB_BOVIN Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment...) gb|AAA93189.1| visual pigment gb|AAB50158.1| blue cone pigment protein [Bos taurus] NP_776992.1 0.0 88% ...

  2. NCBI nr-aa BLAST: CBRC-SARA-01-1959 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1959 ref|NP_000829.1| glutamate receptor, metabotropic 1 [Homo sapiens...] sp|Q13255|MGR1_HUMAN Metabotropic glutamate receptor 1 precursor (mGluR1) gb|AAB05337.1| metabotropic glut...amate receptor 1 alpha gb|EAW47835.1| glutamate receptor, metabotropic 1, isoform CRA_b [Homo sapiens] NP_000829.1 1e-122 94% ...

  3. NCBI nr-aa BLAST: CBRC-SARA-01-1188 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1188 ref|NP_000829.1| glutamate receptor, metabotropic 1 [Homo sapiens...] sp|Q13255|MGR1_HUMAN Metabotropic glutamate receptor 1 precursor (mGluR1) gb|AAB05337.1| metabotropic glut...amate receptor 1 alpha gb|EAW47835.1| glutamate receptor, metabotropic 1, isoform CRA_b [Homo sapiens] NP_000829.1 1e-122 75% ...

  4. NCBI nr-aa BLAST: CBRC-SARA-01-0123 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0123 dbj|BAF32759.1| taste receptor, type 1, member 3 [Sus scrofa domestic...a] dbj|BAF32761.1| taste receptor, type 1, member 3 [Sus scrofa domestica] dbj|BAF32762.1| taste recepto...r, type 1, member 3 [Sus scrofa domestica] dbj|BAF32763.1| taste receptor, type 1, member 3 [Sus scrofa domestica] BAF32759.1 1e-120 70% ...

  5. NCBI nr-aa BLAST: CBRC-SARA-01-1400 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1400 gb|AAW70053.1| MRGX2 [Homo sapiens] gb|AAW70054.1| MRGX2 [Homo sapie...ns] gb|AAW70055.1| MRGX2 [Homo sapiens] gb|AAW70070.1| MRGX2 [Homo sapiens] gb|AAW70083.1| MRGX2 [Homo sapiens] AAW70053.1 4e-34 52% ...

  6. NCBI nr-aa BLAST: CBRC-SARA-01-0756 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0756 gb|AAW70053.1| MRGX2 [Homo sapiens] gb|AAW70054.1| MRGX2 [Homo sapie...ns] gb|AAW70055.1| MRGX2 [Homo sapiens] gb|AAW70070.1| MRGX2 [Homo sapiens] gb|AAW70083.1| MRGX2 [Homo sapiens] AAW70053.1 1e-66 52% ...

  7. NCBI nr-aa BLAST: CBRC-SARA-01-0259 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0259 ref|NP_001029267.1| tubulin, alpha, ubiquitous [Pan troglodytes] ...sp|Q5R1W4|TBA1B_PANTR Tubulin alpha-1B chain (Tubulin alpha-ubiquitous chain) (Alpha-tubulin ubiquitous) (Tu...bulin K-alpha-1) dbj|BAD74034.1| ubiquitous alpha-tubulin [Pan troglodytes verus] NP_001029267.1 1e-136 86% ...

  8. The Remote Observatories of the Southeastern Association for Research in Astronomy (SARA)

    Science.gov (United States)

    Keel, William C.; Oswalt, Terry; Mack, Peter; Henson, Gary; Hillwig, Todd; Batcheldor, Daniel; Berrington, Robert; De Pree, Chris; Hartmann, Dieter; Leake, Martha; Licandro, Javier; Murphy, Brian; Webb, James; Wood, Matt A.

    2017-01-01

    We describe the remote facilities operated by the Southeastern Association for Research in Astronomy (SARA) , a consortium of colleges and universities in the US partnered with Lowell Observatory, the Chilean National Telescope Allocation Committee, and the Instituto de Astrofísica de Canarias. SARA observatories comprise a 0.96 m telescope at Kitt Peak, Arizona; one of 0.6 m aperture on Cerro Tololo, Chile; and the 1 m Jacobus Kapteyn Telescope at the Roque de los Muchachos, La Palma, Spain. All are operated using standard VNC or Radmin protocols communicating with on-site PCs. Remote operation offers considerable flexibility in scheduling, allowing long-term observational cadences difficult to achieve with classical observing at remote facilities, as well as obvious travel savings. Multiple observers at different locations can share a telescope for training, educational use, or collaborative research programs. Each telescope has a CCD system for optical imaging, using thermoelectric cooling to avoid the need for frequent local service, and a second CCD for offset guiding. The Arizona and Chile telescopes also have fiber-fed echelle spectrographs. Switching between imaging and spectroscopy is very rapid, so a night can easily accommodate mixed observing modes. We present some sample observational programs. For the benefit of other groups organizing similar consortia, we describe the operating structure and principles of SARA, as well as some lessons learned from almost 20 years of remote operations.

  9. Impact of subacute ruminal acidosis (SARA) adaptation on rumen microbiota in dairy cattle using pyrosequencing.

    Science.gov (United States)

    Mao, S Y; Zhang, R Y; Wang, D S; Zhu, W Y

    2013-12-01

    The objective of this study was to evaluate the changes in bacterial populations in the rumen of dairy cattle following adaptation to subacute ruminal acidosis (SARA) using 16S rRNA gene pyrosequencing. Rumen contents were collected from four cattle adapted to either a 40% (control diet, COD) or 70% (SARA induction diet, SAID) concentrate feeds. DNA was extracted from each of the samples. Bacterial 16S rRNA genes of ruminal DNA extracts were PCR amplified with 2 bar coded primer sets and sequenced by 454 pyrosequencing. At a high taxonomic level, the percentage of Proteobacteria and Bacteroidetes were reduced by SAID feeding, whereas Firmicutes and Actinobacteria were more abundant in the SAID than in the COD group. At the genus level, as compared with the COD group, the abundances of Prevotella, Treponema, Anaeroplasma, Papillibacter, Acinetobacter and unclassified populations including unclassified Lentisphaerae, and unclassified bacteria were lower (P rumen microbial community. Taken together, our findings provide a comprehensive picture of current knowledge of the community structure of the rumen bacterial ecosystem during SARA, and enhance our understanding about the ruminal microbial ecology that may be useful in the prevention of ruminal acidosis. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Innovative Stormwater Quality Tools by SARA for Holistic Watershed Master Planning

    Science.gov (United States)

    Thomas, S. M.; Su, Y. C.; Hummel, P. R.

    2016-12-01

    Stormwater management strategies such as Best Management Practices (BMP) and Low-Impact Development (LID) have increasingly gained attention in urban runoff control, becoming vital to holistic watershed master plans. These strategies can help address existing water quality impairments and support regulatory compliance, as well as guide planning and management of future development when substantial population growth and urbanization is projected to occur. However, past efforts have been limited to qualitative planning due to the lack of suitable tools to conduct quantitative assessment. The San Antonio River Authority (SARA), with the assistance of Lockwood, Andrews & Newnam, Inc. (LAN) and AQUA TERRA Consultants (a division of RESPEC), developed comprehensive hydrodynamic and water quality models using the Hydrological Simulation Program-FORTRAN (HSPF) for several urban watersheds in the San Antonio River Basin. These models enabled watershed management to look at water quality issues on a more refined temporal and spatial scale than the limited monitoring data. They also provided a means to locate and quantify potential water quality impairments and evaluate the effects of mitigation measures. To support the models, a suite of software tools were developed. including: 1) SARA Timeseries Utility Tool for managing and processing of large model timeseries files, 2) SARA Load Reduction Tool to determine load reductions needed to achieve screening levels for each modeled constituent on a sub-basin basis, and 3) SARA Enhanced BMP Tool to determine the optimal combination of BMP types and units needed to achieve the required load reductions. Using these SARA models and tools, water quality agencies and stormwater professionals can determine the optimal combinations of BMP/LID to accomplish their goals and save substantial stormwater infrastructure and management costs. The tools can also help regulators and permittees evaluate the feasibility of achieving compliance

  11. Reactivity of Athabasca residue and of its SARA fractions during residue hydroconversion

    Energy Technology Data Exchange (ETDEWEB)

    Verstraete, J.; Danial-Fortain, P.; Gauthier, T.; Merdrignac, I. [IFP-Lyon, Vermaison (France); Budzinski, H. [Bordeaux Univ. (France). ISM-LPTC, UMR CNRS

    2009-07-01

    Residue conversion processes are becoming increasingly important because of the declining market for residual fuel oil and a greater demand for middle distillates. Ebullated-bed hydroconversion is a commercially proven technology for converting heavy feedstocks with high amounts of impurities. The process enables the conversion of atmospheric or vacuum residues at temperatures up to 440 degrees C, and at liquid hourly space velocity (LHSV) conditions in the range of 0.15 to 0.5 per hour. A 540 degrees C conversion of up to 80 weight per cent can be achieved under these conditions. This paper reported on a research study conducted at IFP Lyon in which the residue hydroconversion in a large-scale ebullated bed bench unit was investigated to determine the impact of operating conditions and feed properties on yield and product qualities. Hydrogen was added to the feed in the bench units to keep a high hydrogen partial pressure and favour the catalytic hydroconversion reactions. In a typical test, the reactor was fed with 50 g of feedstock and 0.45 g of crushed equilibrium industrial NiMo catalyst, pressurized hydrogen and quickly heated at the reaction temperature. This paper also discussed the conversion of Athabasca bitumen residue in the large-scale pilot plant and also in the small scale batch reactor. The effect of operating temperature and space velocity was examined. The reactivity of the saturates, aromatics, resins and asphaltenes (SARA) fractions of the bitumen was studied separately in order to better understand the conversion mechanisms and reactivities. The Athabasca bitumen feed and SARA fractions were also analyzed in terms of standard petroleum analysis, SARA fractionation, elemental analysis, size exclusion chromatography (SEC) and 13C NMR. Hydroconversion experiments were conducted in the batch unit at different reaction temperatures and reaction times. A comparison of small-scale batch results with those obtained with the continuous large-scale bench

  12. Residual radioactivity at the Milan AVF cyclotron

    Science.gov (United States)

    Birattari, C.; Cantone, M. C.; Ferrari, A.; Silari, M.

    1989-08-01

    γ-ray spectrometry measurements have been carried out at the Cyclotron Laboratory at the Department of Physics of the University of Milan, to evaluate the levels of residual radioactivity after about one year from shut down. Measurements were performed inside the cyclotron and at several points in the accelerator vault and target room, as well as on specific components removed from the beam transport system, on samples of the concrete shields and on residues taken from the cyclotron vacuum chamber. The radionuclides identified and the values of specific activity and dose rate are reported. The results indicate that no particular hazard and waste disposal problems should be encountered at the time of the decommissioning of the facility.

  13. Improving cancer treatment with cyclotron produced radionuclides

    Energy Technology Data Exchange (ETDEWEB)

    Larson, S.M. Finn, R.D.

    1992-08-04

    This report describes the author's continuing long term goal of promoting nuclear medicine applications by improving the scientific basis for tumor diagnosis treatment and treatment follow-up based on the use of cyclotron produced radiotracers in oncology. The program has 3 interactive components: Radiochemistry /Cyclotron; Pharmacology; and Immunology. An essential strategy is as follows: novel radionuclides and radiotracers developed in the Radiochemistry/Cyclotron section under the DOE grant during the 1989--1992 grant period, will be employed in the Pharmacology and Immunology sections of the DOE grant during the 1992--1995 grant period. The development of novel radionuclides and tracers is of course useful in and of itself, but their utility is greatly enhanced by the interaction with the immunology and pharmacology components of the program.

  14. A line-of-sight electron cyclotron emission receiver for electron cyclotron resonance heating feedback control of tearing modes

    DEFF Research Database (Denmark)

    Oosterbeek, J.W.; Bürger, A.; Westerhof, E.

    2008-01-01

    An electron cyclotron emission (ECE) receiver inside the electron cyclotron resonance heating (ECRH) transmission line has been brought into operation. The ECE is extracted by placing a quartz plate acting as a Fabry-Perot interferometer under an angle inside the electron cyclotron wave (ECW) beam...

  15. Electron cyclotron resonance heating on TEXTOR

    NARCIS (Netherlands)

    Westerhof, E.; Hoekzema, J. A.; Hogeweij, G. M. D.; Jaspers, R. J. E.; Schüller, F. C.; Barth, C. J.; Bongers, W. A.; Donne, A. J. H.; Dumortier, P.; van der Grift, A. F.; van Gorkom, J. C.; Kalupin, D.; Koslowski, H. R.; Kramer-Flecken, A.; Kruijt, O. G.; Cardozo, N. J. L.; Mantica, P.; van der Meiden, H. J.; Merkulov, A.; Messiaen, A.; Oosterbeek, J. W.; Oyevaar, T.; Poelman, A. J.; Polman, R. W.; Prins, P. R.; Scholten, J.; Sterk, A. B.; Tito, C. J.; Udintsev, V.S.; Unterberg, B.; Vervier, M.; van Wassenhove, G.

    2003-01-01

    The 110 GHz and the new 140 GHz gyrotron systems for electron cyclotron resonance heating (ECRH) and ECCD on TEXTOR are described and results of ECRH experiments with the 110 GHz system are reported. Central ECRH on Ohmic plasmas shows the presence of an internal electron transport barrier near q =

  16. Microwave power coupling with electron cyclotron resonance ...

    Indian Academy of Sciences (India)

    Electron cyclotron resonance (ECR) plasma was produced at 2.45 GHz using 200 – 750 W microwave power. The plasma was produced from argon gas at a pressure of 2 × 10−4 mbar. Three water-cooled solenoid coils were used to satisfy the ECR resonant conditions inside the plasma chamber. The basic parameters of ...

  17. The Data Cyclotron query processing scheme

    NARCIS (Netherlands)

    Goncalves, R.; Kersten, M.

    2011-01-01

    A grand challenge of distributed query processing is to devise a self-organizing architecture which exploits all hardware resources optimally to manage the database hot set, minimize query response time, and maximize throughput without single point global coordination. The Data Cyclotron

  18. The Data Cyclotron query processing scheme.

    NARCIS (Netherlands)

    R.A. Goncalves (Romulo); M.L. Kersten (Martin)

    2011-01-01

    htmlabstractA grand challenge of distributed query processing is to devise a self-organizing architecture which exploits all hardware resources optimally to manage the database hot set, minimize query response time, and maximize throughput without single point global coordination. The Data Cyclotron

  19. Electron-cyclotron-resonance ion sources (review)

    Energy Technology Data Exchange (ETDEWEB)

    Golovanivskii, K.S.; Dougar-Jabon, V.D. [People`s Friendship Univ., Moscow (Russian Federation)

    1992-01-01

    The physical principles are described and a brief survey of the present state is given of ion sources based on electron-cyclotron heating of plasma in a mirror trap. The characteristics of ECR sources of positive and negative ions used chiefly in accelerator technology are presented. 20 refs., 10 figs., 3 tabs.

  20. <600> MeV synchro-cyclotron

    CERN Multimedia

    CERN PhotoLab

    1971-01-01

    One of the 14 pancakes of the new magnet coils for the 600 MeV synchro-cyclotron which were wound and coated with epoxy resin on the CERN site. These new coils will replace the present ones which have been in use for more than 14 years but are now showing signs of deteriorations.

  1. Development of the cyclotron radioisotope production technology

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Yong Sup; Chun, K.S.; Yang, S.D.; Lee, J.D.; Ahn, S.H.; Yun, Y.K.; Park, H.; Lee, J.S.; Chai, J.S.; Kim, U.S.; Hong, S.S.; Lee, M.Y.; Park, C.W.; Baik, S. K.; Kim, E. H.; Kim, T. K.; Kim, K. S.; Kim, J. H

    1999-04-01

    The purpose of this study is to contribute the advance of nuclear medicine and to the improvement of human health through the development of various accelerator radionuclides and mass production with automization of production. The results obtained from this study are following: 1) In order to introduce 30 MeV high current cyclotron, the specification of cyclotron has been made, the building site was selected and we drew the draw-up of cyclotron. The cyclotron installation contract was postponed until the financial resources could be secured. 2) For a development high purity 1-123 producing system, a Xe-124 target system, a temperature measurement system of the inner part of the target and a target window were fabricated. A Xe-124 gas target recovery system and a full production system of 1-123 was drew up. 3) For a development of a therapeutic nuclide At-211, a target for the production of At-211 via {sup 209}Bi(alpha, 2n) reaction was fabricated. Produced At-211 was separated by distillation method. 4) For development of beta-emitting nuclides, Ti-45, C-11, F{sub 2}-18, beam irradiation system suitable for each target were fabricated. 5) For automatic production of Ga-67, automated module and PLC program was made 6) For the quality control of radiopharmaceuticals, analytical method of thallium and copper by polarography was investigated and established.

  2. Resonant cyclotron scattering in magnetars' emission

    NARCIS (Netherlands)

    Rea, N.; Zane, S.; Turolla, R.; Lyutikov, M.; Götz, D.

    2008-01-01

    We present a systematic fit of a model of resonant cyclotron scattering (RCS) to the X-ray data of 10 magnetars, including canonical and transient anomalous X-ray pulsars (AXPs) and soft gamma repeaters (SGRs). In this scenario, nonthermal magnetar spectra in the soft X-rays (i.e., below ~10 keV)

  3. Ion cyclotron resonance heating system on Aditya

    Indian Academy of Sciences (India)

    R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

    1Institute for Plasma Research, Bhat, Gandhinagar 382 428, India. 2Variable Electron Cyclotron .... Requirements for RF generators for fusion research include high power, long pulse duration and reliability. ... Output of pre-driver (triode 3CX5000A7) grounded grid amplifier is made tunable within. 20 to 47 MHz by using a ...

  4. Program Complex For Cyclotron Beam Dynamic Simulations

    CERN Document Server

    Glazov, A A; Karamysheva, G A; Lisenkova, O E

    2004-01-01

    The program complex in MATLAB intended for particle dynamic simulations is described. Programming in an easy-to-use environment permits creation of models in a short space of time. Advanced graphical tools of MATLAB give good visualization features to created models. The beam dynamic modelling results by the example of two different cyclotron designs are presented.

  5. SC Cyclotron and RIB Facilities in Kolkata

    CERN Document Server

    Sinha, Bikash; Chakrabarti, Alok

    2005-01-01

    The superconducting cyclotron under construction at this Centre has bending limit (K-bend) of 520 and focusing limit (K-foc) of 160. It is being constructed, primarily, for nuclear physics experiments with heavy ion beams at intermediate energies. The 100-ton main magnet is currently in the commissioning phase with the main coil already at 4.2K temperature. Magnetic field measurements will be carried out over the next several months. All other systems of the cyclotron are in an advanced stage of fabrication or development. We plan to start assembly of the complete cyclotron around the end of 2005. In the phase-I of the project one beam line has been provided. Construction of three more beam lines and various experimental facilities for nuclear physics as well as irradiation experiments has also been funded and the work is well on its way. An ISOL type Radioactive Ion Beam (RIB) facility is being built with the existing K=130 room temperature cyclotron, VEC, as the primary beam source. In-beam RIB production a...

  6. Tokamak startup with electron cyclotron heating

    Energy Technology Data Exchange (ETDEWEB)

    Holly, D J; Prager, S C; Shepard, D A; Sprott, J C

    1980-04-01

    Experiments are described in which the startup voltage in a tokamak is reduced by approx. 60% by the use of a modest amount of electron cyclotron resonance heating power for preionization. A 50% reduction in volt-second requirement and impurity reflux are also observed.

  7. Cyclotron-based neutron source for BNCT

    Science.gov (United States)

    Mitsumoto, T.; Yajima, S.; Tsutsui, H.; Ogasawara, T.; Fujita, K.; Tanaka, H.; Sakurai, Y.; Maruhashi, A.

    2013-04-01

    Kyoto University Research Reactor Institute (KURRI) and Sumitomo Heavy Industries, Ltd. (SHI) have developed a cyclotron-based neutron source for Boron Neutron Capture Therapy (BNCT). It was installed at KURRI in Osaka prefecture. The neutron source consists of a proton cyclotron named HM-30, a beam transport system and an irradiation & treatment system. In the cyclotron, H- ions are accelerated and extracted as 30 MeV proton beams of 1 mA. The proton beams is transported to the neutron production target made by a beryllium plate. Emitted neutrons are moderated by lead, iron, aluminum and calcium fluoride. The aperture diameter of neutron collimator is in the range from 100 mm to 250 mm. The peak neutron flux in the water phantom is 1.8×109 neutrons/cm2/sec at 20 mm from the surface at 1 mA proton beam. The neutron source have been stably operated for 3 years with 30 kW proton beam. Various pre-clinical tests including animal tests have been done by using the cyclotron-based neutron source with 10B-p-Borono-phenylalanine. Clinical trials of malignant brain tumors will be started in this year.

  8. Cyclotron-based neutron source for BNCT

    Energy Technology Data Exchange (ETDEWEB)

    Mitsumoto, T.; Yajima, S.; Tsutsui, H.; Ogasawara, T.; Fujita, K. [Sumitomo Heavy Industries, Ltd (Japan); Tanaka, H.; Sakurai, Y.; Maruhashi, A. [Kyoto University Research Reactor Institute (Japan)

    2013-04-19

    Kyoto University Research Reactor Institute (KURRI) and Sumitomo Heavy Industries, Ltd. (SHI) have developed a cyclotron-based neutron source for Boron Neutron Capture Therapy (BNCT). It was installed at KURRI in Osaka prefecture. The neutron source consists of a proton cyclotron named HM-30, a beam transport system and an irradiation and treatment system. In the cyclotron, H- ions are accelerated and extracted as 30 MeV proton beams of 1 mA. The proton beams is transported to the neutron production target made by a beryllium plate. Emitted neutrons are moderated by lead, iron, aluminum and calcium fluoride. The aperture diameter of neutron collimator is in the range from 100 mm to 250 mm. The peak neutron flux in the water phantom is 1.8 Multiplication-Sign 109 neutrons/cm{sup 2}/sec at 20 mm from the surface at 1 mA proton beam. The neutron source have been stably operated for 3 years with 30 kW proton beam. Various pre-clinical tests including animal tests have been done by using the cyclotron-based neutron source with {sup 10}B-p-Borono-phenylalanine. Clinical trials of malignant brain tumors will be started in this year.

  9. Impact of subacute ruminal acidosis (SARA) adaptation and recovery on the density and diversity of bacteria in the rumen of dairy cows

    NARCIS (Netherlands)

    Hook, S.E.; Steele, M.A.; Northwood, K.S.; Dijkstra, J.; France, J.; Wright, A.G.; McBride, B.W.

    2011-01-01

    Subacute ruminal acidosis (SARA) is characterized by ruminal pH depression and microbial perturbation. The impact of SARA adaptation and recovery on rumen bacterial density and diversity was investigated following high-grain feeding. Four ruminally cannulated dairy cows were fed a hay diet,

  10. PLS models for determination of SARA analysis of Colombian vacuum residues and molecular distillation fractions using MIR-ATR

    Directory of Open Access Journals (Sweden)

    Jorge A. Orrego-Ruiz

    2014-06-01

    Full Text Available In this work, prediction models of Saturates, Aromatics, Resins and Asphaltenes fractions (SARA from thirty-seven vacuum residues of representative Colombian crudes and eighteen fractions of molecular distillation process were obtained. Mid-Infrared (MIR Attenuated Total Reflection (ATR spectroscopy in combination with partial least squares (PLS regression analysis was used to estimate accurately SARA analysis in these kind of samples. Calibration coefficients of prediction models were for saturates, aromatics, resins and asphaltenes fractions, 0.99, 0.96, 0.97 and 0.99, respectively. This methodology permits to control the molecular distillation process since small differences in chemical composition can be detected. Total time elapsed to give the SARA analysis per sample is 10 minutes.

  11. NCBI nr-aa BLAST: CBRC-SARA-01-0196 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0196 ref|NP_004164.2| solute carrier family 7 (cationic amino acid tra...nsporter, y+ system), member 4 [Homo sapiens] sp|O43246|CTR4_HUMAN Cationic amino acid transporter 4 (CAT-4)... (CAT4) gb|AAH08814.1| Solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 [Homo ...sapiens] gb|AAI07161.1| Solute carrier family 7 (cationic amino acid transporter,... y+ system), member 4 [Homo sapiens] gb|AAI07162.1| Solute carrier family 7 (cationic amino acid transporter

  12. NCBI nr-aa BLAST: CBRC-SARA-01-0900 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0900 ref|YP_001122232.1| CDP-alcohol phosphatidyltransferase [Francise...lla tularensis subsp. tularensis WY96-3418] ref|YP_001427783.1| CDP-alcohol phosphatidyltransferase [Francis...ella tularensis subsp. holarctica FTA] gb|ABO47111.1| CDP-alcohol phosphatidyltransferase [Francisella tular...ensis subsp. tularensis WY96-3418] gb|EDN35713.1| phosphatidylserine synthase [Francis...ella tularensis subsp. novicida GA99-3549] gb|EDN37179.1| hypothetical protein FTDG_01588 [Francisella

  13. NCBI nr-aa BLAST: CBRC-SARA-01-1761 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1761 ref|NP_000943.1| platelet-activating factor receptor [Homo sapien...s] sp|P25105|PTAFR_HUMAN Platelet-activating factor receptor (PAF-R) gb|AAA60001.1| platelet activating fact...or receptor dbj|BAA01050.1| platelet-activating factor receptor [Homo sapiens] gb|AAB25755.1| platelet-activ...ating factor receptor; PAF receptor [Homo sapiens] gb|AAA60002.1| platelet activa...ting factor receptor gb|AAH13816.1| Platelet-activating factor receptor [Homo sapiens] gb|AAP32298.1| platelet

  14. NCBI nr-aa BLAST: CBRC-SARA-01-1761 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1761 ref|XP_524634.1| PREDICTED: platelet-activating factor receptor i...soform 6 [Pan troglodytes] ref|XP_001151906.1| PREDICTED: platelet-activating factor receptor isoform 1 [Pan... troglodytes] ref|XP_001151960.1| PREDICTED: platelet-activating factor receptor isoform 2 [Pan troglodytes]... ref|XP_001152023.1| PREDICTED: platelet-activating factor receptor isoform 3 [Pa...n troglodytes] ref|XP_001152095.1| PREDICTED: platelet-activating factor receptor isoform 4 [Pan troglodytes

  15. NCBI nr-aa BLAST: CBRC-SARA-01-0019 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0019 ref|NP_031724.2| cholinergic receptor, muscarinic 1, CNS [Mus mus...culus] dbj|BAC38175.1| unnamed protein product [Mus musculus] gb|AAH94242.1| Cholinergic receptor, muscarini...c 1, CNS [Mus musculus] dbj|BAE23612.1| unnamed protein product [Mus musculus] gb|EDL33348.1| cholinergic re...ceptor, muscarinic 1, CNS, isoform CRA_a [Mus musculus] gb|EDL33349.1| cholinergi

  16. Rumen Microbiome Composition in Cattle during Grain-Induced Subacute Ruminal Acidosis (SARA)

    DEFF Research Database (Denmark)

    Danscher, Anne Mette; Derakshani, Hooman; Li, Shucong

    2014-01-01

    Six lactating, rumen cannulated, Danish Holstein cows were used in a blocked design study including two blocks. In the first block, two cows received control diet and two cows received SARA-challenge diet. In the second block, former control cows received SARAdiet while two new cows received....... Differences in bacterial communities between groups were tested based on weighted Unifrac distance using PERMANOVA and partial least square discriminant analysis (PLS-DA). 556,536 high quality sequences were collected, resulting in identification of 18,326 OTUs from 18 phyla of which 81 were classified...

  17. NCBI nr-aa BLAST: CBRC-SARA-01-0771 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0771 ref|NP_848509.1| progestin and adipoQ receptor family member VII ...[Homo sapiens] sp|Q86WK9|MPRA_HUMAN Membrane progestin receptor alpha (mPR alpha) (Progestin and adipoQ rece...ptor family member VII) gb|AAO47233.1|AF313620_1 putative membrane steroid receptor [Homo sapiens] gb|AAR08373.1| progesti...1| hCG1642829 [Homo sapiens] emb|CAM12867.1| progestin and adipoQ receptor family member VII [Homo sapiens] NP_848509.1 1e-178 87% ...

  18. NCBI nr-aa BLAST: CBRC-SARA-01-0033 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0033 ref|NP_000951.1| prostaglandin I2 (prostacyclin) receptor (IP) [H...in I2 receptor) dbj|BAA05008.1| prostacyclin receptor [Homo sapiens] gb|AAA36448.1| prostanoid IP receptor dbj|BAA06110.1| pros...tacyclin receptor [Homo sapiens] dbj|BAA07325.1| prostacyclin ...receptor [Homo sapiens] gb|AAO92301.1| prostaglandin I2 (prostacyclin) receptor [Homo sapiens] gb|AAH75814.1| Prostaglandin I2 (pros...tacyclin) receptor (IP) [Homo sapiens] gb|EAW57432.1| prostaglandin I2 (prostacyclin

  19. NCBI nr-aa BLAST: CBRC-SARA-01-1750 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1750 gb|ABR53744.1| opsin 1 short-wavelength senstive protein [Daubentonia madagascar...iensis] gb|ABR53745.1| opsin 1 short-wavelength senstive protein [Daubentonia madagascariensi...s] gb|ABR53746.1| opsin 1 short-wavelength senstive protein [Daubentonia madagascariensis] gb|ABR53747.1| op...sin 1 short-wavelength senstive protein [Daubentonia madagascariensis] gb|ABR5374...8.1| opsin 1 short-wavelength senstive protein [Daubentonia madagascariensis] gb|ABR53749.1| opsin 1 short-w

  20. NCBI nr-aa BLAST: CBRC-SARA-01-1796 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available HM74) (Protein PUMA-G) dbj|BAC58009.1| nicotinic acid receptor [Rattus norvegicus] gb|EDM13619.1| G protein-coupled receptor 109A [Rattus norvegicus] NP_852141.1 1e-165 78% ... ...us] sp|Q80Z39|GP109_RAT Nicotinic acid receptor (G-protein coupled receptor 109) (G-protein coupled receptor...CBRC-SARA-01-1796 ref|NP_852141.1| G protein-coupled receptor 109A [Rattus norvegic

  1. NCBI nr-aa BLAST: CBRC-SARA-01-0144 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0144 ref|YP_104995.1| alcohol dehydrogenase, zinc-containing [Burkholder...ia mallei ATCC 23344] ref|YP_111924.1| alcohol dehydrogenase [Burkholderia pseudomallei K96243] ref|ZP_004...40487.1| COG1064: Zn-dependent alcohol dehydrogenases [Burkholderia mallei GB8 horse 4] ref|YP_336176.1| alc...ohol dehydrogenase, zinc-containing [Burkholderia pseudomallei 1710b] ref|ZP_0093...0750.1| COG1064: Zn-dependent alcohol dehydrogenases [Burkholderia mallei FMH] ref|ZP_00934487.1| COG1064: Z

  2. NCBI nr-aa BLAST: CBRC-SARA-01-0259 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0259 ref|XP_001107503.1| PREDICTED: tubulin, alpha, ubiquitous isoform... 10 [Macaca mulatta] ref|XP_001107562.1| PREDICTED: tubulin, alpha, ubiquitous isoform 11 [Macaca mulatta] r...ef|XP_001107624.1| PREDICTED: tubulin, alpha, ubiquitous isoform 12 [Macaca mulatta] ref|XP_001107684.1| PRE...| PREDICTED: tubulin, alpha, ubiquitous isoform 14 [Macaca mulatta] ref|XP_001107805.1| PREDICTED: tubulin, alpha, ubiquitous... isoform 15 [Macaca mulatta] ref|XP_001107870.1| PREDICTED: tubulin, alpha, ubiquitous isof

  3. EBCO Technologies TR Cyclotrons, Dynamics, Equipment, and Applications

    Science.gov (United States)

    Johnson, R. R.; Erdman, K. L.; Gyles, Wm.; Burbee, J.; VanLier, E.; Kovacs, M.; Perron, F.

    2003-08-01

    The Ebco Technologies TR cyclotrons have a common parent in the 500 MeV negative ion cyclotron at TRIUMF in Vancouver. As such, the TR cyclotrons have features that can be adapted for specific application. The cyclotron design is modularized into ion source and injection system, central region and then extraction. The cyclotron ion source is configured for cyclotron beam currents ranging from 50 microAmps to 2 milliAmps. The injection line can be operated in either continuous (CW) or in pulsed mode. The center region of the cyclotron is configured to match the ion source configuration. The extracted beams are directed either to a local target station or to beam lines and thence to target stations. There has been development both in solid, liquid and gas targets. There has been development in radioisotope handling techniques, target material recovery and radiochemical synthesis.

  4. First Results on the Epoch of Reionization from First Light with SARAS 2

    Science.gov (United States)

    Singh, Saurabh; Subrahmanyan, Ravi; Udaya Shankar, N.; Sathyanarayana Rao, Mayuri; Fialkov, Anastasia; Cohen, Aviad; Barkana, Rennan; Girish, B. S.; Raghunathan, A.; Somashekar, R.; Srivani, K. S.

    2017-08-01

    Long-wavelength spectral distortions in the cosmic microwave background arising from the 21 cm transition in neutral hydrogen are a key probe of the Cosmic Dawn and the Epoch of Reionization. These features may reveal the nature of the first stars and ultra-faint galaxies that transformed the spin temperature and ionization state of the primordial gas. SARAS 2 is a spectral radiometer purposely designed for the precision measurement of these monopole or all-sky global 21 cm spectral distortions. We use 63 hr nighttime observations of the radio background in the frequency band 110-200 MHz, with the radiometer deployed at the Timbaktu Collective in Southern India, to derive likelihoods for plausible redshifted 21 cm signals predicted by theoretical models. First light with SARAS 2 disfavors the class of models that feature weak X-ray heating (with {f}X≤slant 0.1) and rapid reionization (with peak \\tfrac{{{dT}}b}{{dz}}≥slant 120 mK per unit redshift interval).

  5. Fourier Transform Ion Cyclotron Resonance Mass Spectrometry at the Cyclotron Frequency.

    Science.gov (United States)

    Nagornov, Konstantin O; Kozhinov, Anton N; Tsybin, Yury O

    2017-04-01

    The phenomenon of ion cyclotron resonance allows for determining mass-to-charge ratio, m/z, of an ensemble of ions by means of measurements of their cyclotron frequency, ω c . In Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS), the ω c quantity is usually unavailable for direct measurements: the resonant state is located close to the reduced cyclotron frequency (ω+), whereas the ω c and the corresponding m/z values may be calculated via theoretical derivation from an experimental estimate of the ω+ quantity. Here, we describe an experimental observation of a new resonant state, which is located close to the ω c frequency and is established because of azimuthally-dependent trapping electric fields of the recently developed ICR cells with narrow aperture detection electrodes. We show that in mass spectra, peaks close to ω+ frequencies can be reduced to negligible levels relative to peaks close to ω c frequencies. Due to reduced errors with which the ω c quantity is obtained, the new resonance provides a means of cyclotron frequency measurements with precision greater than that achieved when ω+ frequency peaks are employed. The described phenomenon may be considered for a development into an FT-ICR MS technology with increased mass accuracy for applications in basic research, life, and environmental sciences. Graphical Abstract ᅟ.

  6. Case Study of East Mississippi Community College's Plan to Assist the Sara Lee Corporation Employees Due to Plant Closing

    Science.gov (United States)

    Hanson, Bruce J.

    2012-01-01

    The aim or purpose of this study was to statistically determine whether there were significant differences in obtaining employment and wages after training provided by East Mississippi Community College (EMCC). The training was specifically provided to employees of Sara Lee Corporation, LLC, after the massive layoff when the company closed its…

  7. Operation of a quasioptical electron cyclotron maser

    Energy Technology Data Exchange (ETDEWEB)

    Morse, E.C.; Pyle, R.V.

    1984-12-01

    The electron cyclotron maser or gyrotron concept has been developed to produce sources producing 200 kW at 28 GHz continuously, and higher power outputs and frequencies in pulsed mode. These sources have been useful in electron cyclotron resonance heating (ECRH) in magnetically confined fusion devices. However, higher frequencies and higher power levels will be required in reactor-grade fusion plasmas, with likely requirements of 1.0 MW or more per source at 140 GHz. Conventional gyrotrons follow a trend of decreasing power for increasing frequency. In order to circumvent this problem, the quasioptical electron cyclotron maser was proposed. In this device, the closed resonator of the conventional gyrotron is replaced with an open, Fabry-Perot type resonator. The cavity modes are then the TEM-type modes of an optical laser. The advantage of this configuration is that the cavity size is not a function of frequency, since the length can be any half-integer number of wavelengths. Furthermore, the beam traverses across the cavity transverse to the direction of radiation output, and thus the rf window design is less complicated than in conventional tubes. The rf output, if obtained by diffraction coupling around one of the mirrors, could be in a TEM mode, which would allow for quasioptical transmission of the microwaves into the plasma in fusion devices. 4 references, 1 figure.

  8. Beam stripping extraction from the VINCY cyclotron

    Directory of Open Access Journals (Sweden)

    Ristić-Đurović Jasna L.

    2006-01-01

    Full Text Available The extraction system of a cyclotron guides an ion beam from a spiral acceleration orbit, through an extraction trajectory, into a high energy transport line. The two methods commonly used to direct an ion into the extraction path are deflection, by the electric field of an electrostatic deflector, and ion stripping, by a thin carbon foil. Compared to the electrostatic deflector system, the stripping extraction provides a fast and easy change of the extracted ion energy and is easier to manufacture operate, and maintain. However, the extraction trajectory and dynamics of an ion beam after stripping are highly dependant on the ion energy and specific charge. Thus, when a multipurpose machine such as the VINCY Cyclotron is concerned, it is far from easy to deliver a variety of ion beams into the same high energy transport line and at the same time preserve a reasonable compactness of the extraction system. The front side stripping extraction system of the VINCY Cyclotron provides high (~70 MeV and mid (~30 MeV energy protons, as well as a number of heavy ions in broad energy ranges. The back side stripping extraction system extracts low energy protons (~18 MeV and enables their simultaneous use with high energy protons at the front side of the machine.

  9. Changes in Microbiota in Rumen Digesta and Feces Due to a Grain-Based Subacute Ruminal Acidosis (SARA) Challenge.

    Science.gov (United States)

    Plaizier, Jan C; Li, Shucong; Danscher, Anne Mette; Derakshani, Hooman; Andersen, Pia H; Khafipour, Ehsan

    2017-08-01

    The effects of a grain-based subacute ruminal acidosis (SARA) challenge on bacteria in the rumen and feces of lactating dairy cows were determined. Six lactating, rumen-cannulated Danish Holstein cows were used in a cross-over study with two periods. Periods included two cows on a control diet and two cows on a SARA challenge. The control diet was a total mixed ration containing 45.5% dry matter (DM), 43.8% DM neutral detergent fiber, and 19.6% DM starch. The SARA challenge was conducted by gradually substituting the control diet with pellets containing 50% wheat and 50% barley over 3 days to reach a diet containing 55.6% DM, 31.3% DM neutral detergent fiber, and 31.8% DM starch, which was fed for four more days. Rumen fluid samples were collected at day 7 and 10 of experimental periods. Feces samples were collected on days 8 and 10 of these periods. Extracted DNA from the rumen and feces samples was analyzed to assess their bacterial communities using MiSeq Illumina sequencing of the V4 region of the 16S rRNA gene. The induction of SARA reduced the richness, diversity, and stability of bacterial communities and resulted in distinctly different microbiota in the rumen and feces. Bacteroidetes and Firmicutes were the most abundant phyla and, combined, they represented 76.9 and 94.4% of the bacterial community in the rumen fluid and the feces, respectively. Only the relative abundance of Firmicutes in the rumen was increased by the SARA challenge. In rumen fluid and feces, the abundances of nine out of the 90 and 25 out of the 89 taxa, respectively, were affected by the challenge. Hence, SARA challenge altered the composition of the bacterial community at the lower taxonomical level in the feces and therefore also likely in the hindgut, as well as in the rumen. However, only reductions in the bacterial richness and diversity in the rumen fluid and feces were in agreement with those of other studies and had a biological basis. Although the composition of the

  10. NCBI nr-aa BLAST: CBRC-SARA-01-1942 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1942 ref|NP_000669.1| alpha-1D-adrenergic receptor [Homo sapiens] sp|P...25100|ADA1D_HUMAN Alpha-1D adrenergic receptor (Alpha 1D-adrenoceptor) (Alpha 1D-adrenoreceptor) (Alpha-1A adrenerg...ic receptor) (Alpha adrenergic receptor 1a) gb|AAB60351.1| adrenergic alpha-1a receptor protein gb|AA...B59487.1| alpha 1a/d adrenergic receptor dbj|BAA06222.1| alpha1A/D adrenergic rec...eptor [Homo sapiens] emb|CAH70478.1| adrenergic, alpha-1D-, receptor [Homo sapiens] emb|CAC00601.2| adrenerg

  11. NCBI nr-aa BLAST: CBRC-SARA-01-1475 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1475 ref|NP_062545.1| taste receptor T2R1 [Homo sapiens] sp|Q9NYW7|TA2R1_HUMAN Taste... receptor type 2 member 1 (T2R1) (Taste receptor family B member 7) (TRB7) gb|AAF43902.1|AF227129_1 candidate taste... receptor T2R1 [Homo sapiens] gb|AAU21051.1| taste receptor T2R1 [Homo sapiens] gb|AAI01732.1| Taste... receptor T2R1 [Homo sapiens] gb|AAI01730.1| Taste receptor, type 2,... member 1 [Homo sapiens] gb|EAX08075.1| taste receptor, type 2, member 1 [Homo sapiens] NP_062545.1 8e-77 51% ...

  12. NCBI nr-aa BLAST: CBRC-SARA-01-1746 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1746 ref|NP_705806.1| non-imprinted in Prader-Willi/Angelman syndrome ...1 [Mus musculus] sp|Q8BHK1|NIPA1_MOUSE Non-imprinted in Prader-Willi/Angelman syndrome region protein 1 homo...log gb|AAM34534.1| non-imprinted in Prader-Willi/Angelman syndrome 1 [Mus musculus] dbj|BAC32809.1| unnamed ...protein product [Mus musculus] gb|AAH55828.1| Non imprinted in Prader-Willi/Angel...man syndrome 1 homolog (human) [Mus musculus] gb|EDL21870.1| non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human) [Mus musculus] NP_705806.1 1e-113 81% ...

  13. NCBI nr-aa BLAST: CBRC-SARA-01-0185 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0185 ref|NP_000852.1| histamine receptor H1 [Homo sapiens] ref|NP_001091681.1| histamine... receptor H1 [Homo sapiens] ref|NP_001091682.1| histamine receptor H1 [Homo sapiens] ref|NP_001091683.1| histamine... receptor H1 [Homo sapiens] sp|P35367|HRH1_HUMAN Histamine H1 receptor emb|CAA54182.1| histamine... H1 receptor [Homo sapiens] dbj|BAA05840.1| histamine H1 receptor [Ho...mo sapiens] emb|CAA84380.1| Human histamine H1 receptor [Homo sapiens] dbj|BAA03319.1| histamine H1 receptor

  14. NCBI nr-aa BLAST: CBRC-SARA-01-0948 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-0948 ref|NP_473371.1| MAS-related GPR, member X2 [Homo sapiens] sp|Q96...LB1|MRGX2_HUMAN Mas-related G-protein coupled receptor member X2 gb|AAK91805.1| G protein-coupled receptor [Homo sapie...ns] dbj|BAB89339.1| putative G-protein coupled receptor [Homo sapiens] dbj|BAC06030.1| seven trans...membrane helix receptor [Homo sapiens] gb|AAH63450.1| MAS-related GPR, member X2 [Homo sapie...ns] gb|AAW70056.1| MRGX2 [Homo sapiens] gb|AAW70057.1| MRGX2 [Homo sapiens] gb|AAW70058.1| MRGX2 [Homo sapie

  15. NCBI nr-aa BLAST: CBRC-SARA-01-1066 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SARA-01-1066 ref|NP_473371.1| MAS-related GPR, member X2 [Homo sapiens] sp|Q96...LB1|MRGX2_HUMAN Mas-related G-protein coupled receptor member X2 gb|AAK91805.1| G protein-coupled receptor [Homo sapie...ns] dbj|BAB89339.1| putative G-protein coupled receptor [Homo sapiens] dbj|BAC06030.1| seven trans...membrane helix receptor [Homo sapiens] gb|AAH63450.1| MAS-related GPR, member X2 [Homo sapie...ns] gb|AAW70056.1| MRGX2 [Homo sapiens] gb|AAW70057.1| MRGX2 [Homo sapiens] gb|AAW70058.1| MRGX2 [Homo sapie

  16. Monitoring the Continuum Emission from Active Galactic Nuclei with the SARA 0.9-m Telescope

    Science.gov (United States)

    Rumstay, K. S.; Morrill, A. L.

    1995-12-01

    CCD images of seven active galactic nuclei were obtained during the period July 7-11 1995 with the 0.9-m telescope operated at Kitt Peak by the Southeastern Association for Research in Astronomy (SARA). Six of these objects (Mrk 335, Mrk 590, NGC 4151, NGC 5548, Mrk 817, and Mrk 509) are Seyfert galaxies; the seventh is the broad-line radio galaxy 3C-390.3. The objects were selected from the sample of eleven active galactic nuclei whose emission spectra are routinely monitored with the Ohio State University 1.8-m telescope in Flagstaff, Arizona. These observations mark the beginning of a continuing program to use the SARA observing facility to monitor the continuum emission from these eleven AGNs. Data from this program will be applied to efforts to place constraints on the sizes and geometries of the AGN broad-line regions by the method of reverberation mapping. The BVRI images were obtained with an Axiom 2048x2048 zero-defect CCD array. The observing run was hampered by frequent scattered clouds, limiting the accuracy with which magnitudes could be calibrated. However, the wide field (9.38x9.38 arcmin) of the CCD array encompasses several comparison stars in each object field, and permits differential photometry to be performed even under relatively poor sky conditions. Partial support of this work by the National Science Foundation, through the Research Experience for Undergraduates Program, and by the Valdosta State University Center on Faculty Development and Instructional Improvement, is gratefully acknowledged.

  17. Escribiendo el silencio: la contemplación poética de Sara Pujol

    Directory of Open Access Journals (Sweden)

    Gala, Candelas

    2005-06-01

    Full Text Available Reading Sara Pujol Russell's El fuego tiende su aire (1999 and Intacto asombro de la luz del silencio (2001, is entering into a poetic world whose content and form are both innovative and complex. This poetry invites the reader into a state of meditative contemplation that seeks correspondences among different elements in reality as the key to access a superior type of knowledge. Pujol's writing moves in the fringes between voice and silence, art and nature, meaning and nothingness, identity and difference, it seeks to surpass its own verbal texture while only in that texture does it find articulation and only through it does transcendence becones accessible. The focus of the present reading centers on the point where Pujol's language seeks to transcend the disjunction between sign and surrounding, the point where synthesis is fusion about to dissolve.La lectura de El fuego tiende su aire (1999 e Intacto asombro en la luz del silencio (2001 de Sara Pujol Russell, supone la entrada en un discurso poético innovador y complejo tanto en contenido como en forma. Esta poesía invita a una contemplación meditativa que busca las correspondencias entre los diversos elementos de la realidad como clave para acceder a un conocimiento superior. Su escritura se mueve en los bordes entre la voz y el silencio, el arte y la naturaleza, el sentido y el vacío, la identidad y la diferencia, buscando trascender lo que está más allá de su misma urdimbre verbal pero que sólo en ella se configura, y sólo desde ella se puede acceder. En el movimiento de esta escritura por superar la disyunción entre signo y entorno, en esa síntesis a punto de disolverse, es donde se enfoca la lectura en este ensayo.

  18. Benchmarking of codes for electron cyclotron heating and electron cyclotron current drive under ITER conditions

    NARCIS (Netherlands)

    Prater, R.; Farina, D.; Gribov, Y.; Harvey, R. W.; Ram, A. K.; Lin-Liu, Y. R.; Poli, E.; Smirnov, A. P.; Volpe, F.; Westerhof, E.; Zvonkovo, A.

    2008-01-01

    Optimal design and use of electron cyclotron heating requires that accurate and relatively quick computer codes be available for prediction of wave coupling, propagation, damping and current drive at realistic levels of EC power. To this end, a number of codes have been developed in laboratories

  19. Women Empowerment in the Realms of Institutionalized Religion and Patriarchy: El Saadawi’s Firdaus and Yezierska’s Sara as Examples

    National Research Council Canada - National Science Library

    Abdullah K. Shehabat

    2016-01-01

    This paper explains how the two protagonists, Firdaus and Sara, successfully paved their own ways in search of self-liberation despite the authoritarian patriarchy and institutionalized religions that plagued them...

  20. Functional impairment in patients with myotonic dystrophy type 1 can be assessed by an ataxia rating scale (SARA).

    Science.gov (United States)

    DiPaolo, Giovanni; Jimenez-Moreno, Cecilia; Nikolenko, Nikoletta; Atalaia, Antonio; Monckton, Darren G; Guglieri, Michela; Lochmüller, Hanns

    2017-04-01

    Myotonic dystrophy type 1 (DM1) is not characterised by ataxia per se; however, DM1 and ataxia patients show similar disturbances in movement coordination often experiencing walking and balance difficulties, although caused by different underlying pathologies. This study aims to investigate the use of a scale previously described for the assessment and rating of ataxia (SARA) with the hypothesis that it could have utility in DM1 patients as a measure of disease severity and risk of falling. Data from 54 DM1 patients were pulled from the PHENO-DM1 natural history study for analysis. Mean SARA score in the DM1 population was 5.45 relative to the maximum score of eight. A flooring effect (score 0) was observed in mild cases within the sample. Inter-rater and test-retest reliability was high with intraclass coefficients (ICC) of 0.983 and 1.00, respectively. Internal consistency was acceptable as indicated by a Cronbach's alpha of 0.761. Component analysis revealed two principle components. SARA correlated with: (1) all measures of muscle function tested, including quantitative muscle testing of ankle dorsiflexion (r = -0.584*), the 6 min walk test (r = -0.739*), 10 m walk test (r = 0.741*), and the nine hole peg test (r = 0.602*) and (2) measures of disease severity/burden, such as MIRS (r = 0.718*), MDHI (r = 0.483*), and DM1-Activ (r = -0.749*) (*p < 0.001). The SARA score was predicted by an interaction between modal CTG repeat length and age at sampling (r = 0.678, p = 0.003). A score of eight or above predicted the use of a walking aid with a sensitivity of 100% and a specificity of 85.7%. We suggest that further research is warranted to ascertain whether SARA or components of SARA are useful outcome measures for clinical trials in DM1. As a tool, it can be used for gathering information about disease severity/burden and helping to identify patients in need of a walking aid, and can potentially be applied in both research and healthcare

  1. Electron cyclotron emission diagnostics on KSTAR tokamak.

    Science.gov (United States)

    Jeong, S H; Lee, K D; Kogi, Y; Kawahata, K; Nagayama, Y; Mase, A; Kwon, M

    2010-10-01

    A new electron cyclotron emission (ECE) diagnostics system was installed for the Second Korea Superconducting Tokamak Advanced Research (KSTAR) campaign. The new ECE system consists of an ECE collecting optics system, an overmode circular corrugated waveguide system, and 48 channel heterodyne radiometer with the frequency range of 110-162 GHz. During the 2 T operation of the KSTAR tokamak, the electron temperatures as well as its radial profiles at the high field side were measured and sawtooth phenomena were also observed. We also discuss the effect of a window on in situ calibration.

  2. Electron cyclotron emission imaging diagnostic system for Rijnhuizen Tokamak Project

    NARCIS (Netherlands)

    Deng, B.H.; Hsia, R. P.; Domier, C.W.; Burns, S. R.; Hillyer, T. R.; N C Luhmann Jr.,; Oyevaar, T.; Donne, A. J. H.; R. T. P. Team,

    1999-01-01

    A 16-channel electron cyclotron emission (ECE) imaging diagnostic system has been developed and installed on the Rijnhuizen Tokamak Project for measuring plasma electron cyclotron emission with a temporal resolution of 2 mu s. The high spatial resolution of the system is achieved by utilizing a low

  3. Cyclotron Lines: From Magnetic Field Strength Estimators to ...

    Indian Academy of Sciences (India)

    Chandreyee Maitra

    2017-09-12

    Sep 12, 2017 ... With forty years since the discovery of the first cyclotron line in Her X-1, there have been remarkable ... the important results related to cyclotron lines since its discovery and reviews their significance. ... context can provide, to build a complete picture for the physics of accretion and hence X-ray emission in.

  4. Ion–Cyclotron Resonance Frequency Interval Dependence on the O ...

    Indian Academy of Sciences (India)

    Solar corona—ion–cyclotron waves—coronal heating—. Vlasov equation. 1. Introduction. Heating of solar corona is still an active research area. It has recently been suggested that the ion–cyclotron resonance could play a key role in the problem of coronal heating. It is generally argued that various electromagnetic plasma ...

  5. Unstable plasma characteristics in mirror field electron cyclotron ...

    Indian Academy of Sciences (India)

    Electron cyclotron plasma reactor are prone to instabilities in specific input power [3–. 7] region (150–450 watts). ... Electron cyclotron resonance (ECR) plasma technology has become very important for fabrication of very large scale ... left hand polarized (LHP) wave. Shufflbotham and Thomson [4] observed several distinct.

  6. Electron Cyclotron Resonance Heating of a High-Density Plasma

    DEFF Research Database (Denmark)

    Hansen, F. Ramskov

    1986-01-01

    Various schemes for electron cyclotron resonance heating of tokamak plasmas with the ratio of electron plasma frequency to electron cyclotron frequency, "»pe/^ce* larger than 1 on axis, are investigated. In particular, a mode conversion scheme is investigated using ordinary waves at the fundamental...

  7. The Moon observed in Energetic Neutral Atoms: Review of the Scientific Findings from SARA/CENA on board Chandrayaan-1

    Science.gov (United States)

    Vorburger, Audrey; Wurz, Peter; Barabash, Stas; Wieser, Martin; Futaana, Yoshifumi; Bhardwaj, Anil; Dhanya, Mb; Asamura, Kazushi

    2017-04-01

    The Sub-keV Atom Reflecting Analyzer (SARA) instrument on board Chandrayaan-1 was exceptionally successful. The instrument not only achieved all its set science goals but also revealed several hitherto unknown and unexpected properties of the solar wind interaction with the lunar surface. SARA's scientific findings can be divided into two groups based on the nature of the particles detected: The first group contains findings gained from ion measurements (from SWIM, SARA's ion sensor) whereas the second group contains findings gained from energetic neutral atom (ENA) measurements (from CENA, SARA's ENA sensor). Here, we present a review of all scientific findings based on ENA measurements. Since the Moon is constantly bombarded by solar wind ions. Until recently, it was tacitly assumed that the ions that impinge onto the lunar surface are almost completely absorbed, with less than 1% reflection, (e.g. Crider and Vondrak, Adv. Space Res., 2002; Feldman et al., JGR, 2000). However, recent observations conducted showed that on average 16% of the impinging solar wind ions are reflected as ENAs (e.g. McComas et al., GRL, 2009; Wieser et al., PSS, 2009; Vorburger et al., JGR, 2013). The energy spectrum of the reflected ENAs is broader than the spectrum of the incident solar wind protons (Futaana et al., JGR, 2012; Harada et al., JGR, 2014), and the characteristic energy is helium (Vorburger et al., JGR., 2012). With the backscattered proton signal being unexpectedly large, these signals are small in comparison, but persistent nevertheless. Finally, recent CENA data analyses showed that a significant fraction of the solar wind plasma is able to reach far into the lunar nightside surface: CENA measured a 30 deg broad ENA ring parallel to the terminator, with a total flux equal to 1.5% of the total dayside flux (Vorburger et al., GR., 2016). These measurements shed light onto the expansion of plasma into voids as they occur in planetary wakes.

  8. SARAS: a precision system for measurement of the cosmic radio background and signatures from the epoch of reionization

    Science.gov (United States)

    Patra, Nipanjana; Subrahmanyan, Ravi; Raghunathan, A.; Udaya Shankar, N.

    2013-08-01

    SARAS is a correlation spectrometer purpose designed for precision measurements of the cosmic radio background and faint features in the sky spectrum at long wavelengths that arise from redshifted 21-cm from gas in the reionization epoch. SARAS operates in the octave band 87.5-175 MHz. We present herein the system design arguing for a complex correlation spectrometer concept. The SARAS design concept provides a differential measurement between the antenna temperature and that of an internal reference termination, with measurements in switched system states allowing for cancellation of additive contaminants from a large part of the signal flow path including the digital spectrometer. A switched noise injection scheme provides absolute spectral calibration. Additionally, we argue for an electrically small frequency-independent antenna over an absorber ground. Various critical design features that aid in avoidance of systematics and in providing calibration products for the parametrization of other unavoidable systematics are described and the rationale discussed. The signal flow and processing is analyzed and the response to noise temperatures of the antenna, reference termination and amplifiers is computed. Multi-path propagation arising from internal reflections are considered in the analysis, which includes a harmonic series of internal reflections. We opine that the SARAS design concept is advantageous for precision measurement of the absolute cosmic radio background spectrum; therefore, the design features and analysis methods presented here are expected to serve as a basis for implementations tailored to measurements of a multiplicity of features in the background sky at long wavelengths, which may arise from events in the dark ages and subsequent reionization era.

  9. Changes in Microbiota in Rumen Digesta and Feces Due to a Grain-Based Subacute Ruminal Acidosis (SARA) Challenge

    DEFF Research Database (Denmark)

    Plaizier, Jan C.; Li, Shucong; Danscher, Anne Mette

    2017-01-01

    The effects of a grain-based subacute ruminal acidosis (SARA) challenge on bacteria in the rumen and feces of lactating dairy cows were determined. Six lactating, rumen-cannulated Danish Holstein cows were used in a cross-over study with two periods. Periods included two cows on a control diet...... and two cows on a SARA challenge. The control diet was a total mixed ration containing 45.5% dry matter (DM), 43.8% DM neutral detergent fiber, and 19.6% DM starch. The SARA challenge was conducted by gradually substituting the control diet with pellets containing 50% wheat and 50% barley over 3 days...... to reach a diet containing 55.6% DM, 31.3% DM neutral detergent fiber, and 31.8% DM starch, which was fed for four more days. Rumen fluid samples were collected at day 7 and 10 of experimental periods. Feces samples were collected on days 8 and 10 of these periods. Extracted DNA from the rumen and feces...

  10. Komunikasi Terapeutik Perawat dengan Tingkat Kecemasan Pasien Pre-Operasi di Ruang Instalasi Bedah Sentral RSUD Saras Husada Purworejo

    Directory of Open Access Journals (Sweden)

    Warsini Warsini

    2015-07-01

    Full Text Available The symptoms of anxiety relate to medical condition are often found, though there are various incidences for each condition. The surgery is a potential threat that may rise stress reaction either physically or psychologically. One factor that may decrease the level of anxiety of patients is nursing therpeutic communication. The purposes of this study were to know the relationship between nursing therapeutic communication and anxiety level of preoperative patients in central surgical instalation room at RSUD Saras Husada Purworejo. This study was used an observational with a cross sectional design. The population in this study was preoperative patients in central surgical instalation room at RSUD Saras Husada Purworejo. Samples were obtained by accidental sampling technique, which consisted of 81 respondent. Data analysis was done by Kendal Tau test. The results showed that nursing therapeutic communication was 37.0% in a good category. Anxiety level of preoperative patients was 44.4% in average level. The result of Kendall Tau test showed a p-value=0.000 (p<0.05. There was a relationship between nursing therapeutic communication and anxiety level of preoperative patients. In conclusion, there was a relationship between nursing therapeutic communication and anxiety level of preoperative patients in central surgical instalation room at RSUD Saras Husada Purworejo.

  11. Saras Cranes in Palwal District in Southern Haryana are Asking for Immediate Attention for Their Last Rescue Effort

    Directory of Open Access Journals (Sweden)

    Tirshem Kumar Kaushik

    2015-05-01

    Full Text Available Saras Cranes Grus antigone are endangered birds of open wetlands with highly worrying depletion trends being witnessed related with disappearance of marshy and shallow perennial, expansive wetlands throughout northern India. Alongside, massive hunting in 18th, 19th and 20th centuries and even today is another serious cause for their worrisome deterioration. Also, destruction of nests, eggs, fledglings and adults by aboriginals indeliberately or deliberately is causing these cranes to perish sooner than latter, completely. Now, Saras Cranes are found in limited number and domain as four populations in the entire world including India, China, Burma, South East Asia and northern Australia. The population of Indian Saras Crane is pitiably restricted to Etawa and Mainpuri districts of Uttar Pradesh. Stray birds of this species are restricted to Kanha National Park in Madhya Pradesh and in some parts of Gujarat and Assam. It is interesting to note that few pairs have been seen in Faridabad and Palwal districts in southern Haryana, India. These need to be protected and conserved.

  12. High-current cyclotron to drive an electronuclear assembly

    CERN Document Server

    Alenitsky, Yu G

    2002-01-01

    The proposal on creation of a high-current cyclotron complex for driving an electronuclear assembly reported at the 17th Meeting on Accelerators of Charged Particles is discussed. Some changes in the basic design parameters of the accelerator are considered in view of new results obtained in the recent works. It is shown that the cyclotron complex is now the most real and cheapest accelerator for production of proton beams with a power of up to 10 MW. Projects on design of a high-current cyclotron complex for driving an electronuclear subcritical assembly are presented.

  13. Improving cancer treatment with cyclotron produced radionuclides. Progress report

    Energy Technology Data Exchange (ETDEWEB)

    Larson, S.M.; Finn, R.D.

    1993-11-01

    This report describes our continuing long term goal of promoting nuclear medicine applications by improving the scientific basis for tumor diagnosis, treatment and treatment follow-up based on the use of cyclotron produced radiotracers in oncology. The program includes 3 interactive components: Radiochemistry/Cyclotron; Pharmacology; and Immunology. An essential strategy is as follows: novel radionuclides and radiotracers developed in the Radiochemistry/Cyclotron section will be employed in the Pharmacology and Immunology sections during the next year. The development of novel radionuclides and tracers is of course useful in and of itself, but their utility is greatly enhanced by the interaction with the immunology and pharmacology components of the program.

  14. Shielding design of the Mayo Clinic Scottsdale cyclotron vault

    Directory of Open Access Journals (Sweden)

    Riper Kenneth A. Van

    2017-01-01

    Full Text Available Mayo Clinic Scottsdale (Scottsdale, Arizona is building a cyclotron vault containing a cyclotron with adjacent targets and a beam line leading to an external target. The targets are irradiated by high energy (15 to 16.5 MeV protons for the production of radioisotopes. We performed Monte Carlo radiation transport simulations to calculate the radiation dose outside of the vault during irradiation of the cyclotron and external targets. We present the Monte Carlo model including the geometry, sources, and variance reduction methods. Mesh tallies surrounding the vault show the external dose rate is within acceptable limits.

  15. Radiation Monitoring System of 30 MeV Cyclotron

    Directory of Open Access Journals (Sweden)

    Lee Jin-Woo

    2017-01-01

    Full Text Available A state-of-the-art radiation monitoring system was implemented at KAERI for a 30-MeV cyclotron. This system consists of several types of radiation measuring systems for ambient dose equivalent rate measurements of outside photon and neutron areas as well as inside the cyclotron, and monitors the alpha and beta particulates released from a stack, as well as the results of worker contamination at the portal of the cyclotron. In addition, an automatic alarm system is also mounted if there are alarms in the measuring systems.

  16. High-Resolution Ion Cyclotron Mobility Spectrometry

    Science.gov (United States)

    Merenbloom, Samuel I.; Glaskin, Rebecca S.; Henson, Zachary B.; Clemmer, David E.

    2009-01-01

    A novel ion mobility spectrometry instrument incorporating a cyclotron geometry drift tube is presented. The drift tube consists of eight regions, four curved drift tubes and four ion funnels. Packets of ions are propagated around the drift tube by changing the drift field at a frequency that is resonant with the ion’s drift time through each region. The approach trims each packet of ions as it leaves and enters each new region. An electrostatic gate allows ions to be kept in the drift tube for numerous cycles, increasing the ability to resolve specified ions. We demonstrate the approach by isolating the [M+2H]2+ or [M+3H]3+ charge state of substance P as well as individual trisaccharide isomers from a mixture of melezitose and raffinose. Resolving powers in excess of 300 are obtainable with this approach. PMID:19143495

  17. Simulation of cyclotron resonant scattering features

    Directory of Open Access Journals (Sweden)

    Schwarm Fritz-Walter

    2014-01-01

    Full Text Available X-ray binary systems consisting of a mass donating optical star and a highly magnetized neutron star, under the right circumstances, show quantum mechanical absorption features in the observed spectra called cyclotron resonant scattering features (CRSFs. We have developed a simulation to model CRSFs using Monte Carlo methods. We calculate Green’s tables which can be used to imprint CRSFs to arbitrary X-ray continua. Our simulation keeps track of scattering parameters of individual photons, extends the number of variable parameters of previous works, and allows for more flexible geometries. Here we focus on the influence of bulk velocity of the accreted matter on the CRSF line shapes and positions.

  18. Ion cyclotron emission by spontaneous emission

    Energy Technology Data Exchange (ETDEWEB)

    Da Costa, O. [Commission of the European Communities, Abingdon (United Kingdom). JET Joint Undertaking; Gresillon, D. [Ecole Polytechnique, 91 - Palaiseau (France). Lab. de Physique des Milieux Ionises

    1994-07-01

    The goal of the study is to examine whether the spontaneous emission can account for ICE (ion cyclotron emission) experimental results, or part of them. A straightforward approach to plasma emission is chosen, investigating the near equilibrium wave radiation by gyrating ions, and thus building from the majority and fast fusion ions the plasma fluctuations and emission on the fast magnetoacoustic or compressional Alfven wave mode in the IC frequency range. Similarities with the ICE experiments are shown: the emission temperature in the presence of fast ions (even in a very small amount), the strong fast ion emission increase with the harmonic, the fine double-line splitting of each peak, the linear but not proportional increase of the peak width with the harmonic. 3 refs., 2 figs.

  19. An ontology-aware integration of clinical models, terminologies and guidelines: an exploratory study of the Scale for the Assessment and Rating of Ataxia (SARA).

    Science.gov (United States)

    Maarouf, Haitham; Taboada, María; Rodriguez, Hadriana; Arias, Manuel; Sesar, Ángel; Sobrido, María Jesús

    2017-12-06

    Electronic rating scales represent an important resource for standardized data collection. However, the ability to exploit reasoning on rating scale data is still limited. The objective of this work is to facilitate the integration of the semantics required to automatically interpret collections of standardized clinical data. We developed an electronic prototype for the Scale of the Assessment and Rating of Ataxia (SARA), broadly used in neurology. In order to address the modeling challenges of the SARA, we propose to combine the best performances from OpenEHR clinical archetypes, guidelines and ontologies. A scaled-down version of the Human Phenotype Ontology (HPO) was built, extracting the terms that describe the SARA tests from free-text sources. This version of the HPO was then used as backbone to normalize the content of the SARA through clinical archetypes. The knowledge required to exploit reasoning on the SARA data was modeled as separate information-processing units interconnected via the defined archetypes. Each unit used the most appropriate technology to formally represent the required knowledge. Based on this approach, we implemented a prototype named SARA Management System, to be used for both the assessment of cerebellar syndrome and the production of a clinical synopsis. For validation purposes, we used recorded SARA data from 28 anonymous subjects affected by Spinocerebellar Ataxia Type 36 (SCA36). When comparing the performance of our prototype with that of two independent experts, weighted kappa scores ranged from 0.62 to 0.86. The combination of archetypes, phenotype ontologies and electronic information-processing rules can be used to automate the extraction of relevant clinical knowledge from plain scores of rating scales. Our results reveal a substantial degree of agreement between the results achieved by an ontology-aware system and the human experts.

  20. Instructional materials for SARA/OSHA training. Volume 1, General site working training

    Energy Technology Data Exchange (ETDEWEB)

    Copenhaver, E.D.; White, D.A.; Wells, S.M. [Oak Ridge National Lab., TN (United States)

    1988-04-01

    This proposed 24 hour ORNL SARA/OSHA training curriculum emphasizes health and safety concerns in hazardous waste operations as well as methods of worker protection. Consistent with guidelines for hazardous waste site activities developed jointly by National Institute for Occupational Safety and Health, Occupational Safety and Health Administration, US Coast Guard, and the Envirorunental Protection Agency, the program material will address Basic Training for General Site Workers to include: ORNL Site Safety Documentation, Safe Work Practices, Nature of Anticipated Hazards, Handling Emergencies and Self-Rescue, Employee Rights and Responsibilities, Demonstration of Use, Care, and Limitations of Personal Protective, Clothing and Equipment, and Demonstration of Monitoring Equipment and Sampling Techniques. The basic training courses includes major fundamentals of industrial hygiene presented to the workers in a format that encourages them to assume responsibility for their own safety and health protection. Basic course development has focused on the special needs of ORNL facilities. Because ORNL generates chemical wastes, radioactive wastes, and mixed wastes, we have added significant modules on radiation protection in general, as well as modules on radiation toxicology and on radiation protective clothing and equipment.

  1. KOS PENANAMAN (KP DAN KOS SARA HIDUP (KSH DALAM PERAKAUNAN ZAKAT PADI DI MALAYSIA

    Directory of Open Access Journals (Sweden)

    Mohd Shukri Hanapi

    2015-12-01

    Full Text Available Kajian ini bertujuan meneliti dan menganalisis kos penanaman (KP dan kos sara hidup (KSH dalam amalan perakaunan zakat padi di Malaysia, sama ada ia ditolak daripada pendapatan kasar (PK atau pun tidak. Di Malaysia, terdapat pelbagai kaedah perakaunan zakat padi yang diamalkan. Ada negeri yang tidak menolak kedua-dua kos tersebut; ada pula negeri yang menolak KP sahaja; dan ada juga yang bertindak menolak kedua-duanya daripada PK. Persoalannya, kenapakah terdapat negeri yang membenarkan KP ditolak daripada PK sedangkan fatwa yang dikeluarkan oleh majoriti negeri di Malaysia tidak membenarkan KP tersebut ditolak daripada PK? Kenapakah pula terdapat negeri yang bukan sahaja membenarkan penolakan KP, malah turut ditolak KSH? Apakah asas mereka dalam hal ini? Bagi menjawab kesemua persoalan ini, perbincangan dalam kajian ini dibahagikan kepada dua bahagian. Pertama, mengenal pasti KP dan KSH dalam amalan perakaunan zakat padi di Malaysia; dan kedua, menganalisis KP dan KSH dalam amalan perakaunan zakat padi di Malaysia berdasarkan pandangan fuqaha’. Berdasarkan analisis kandungan terhadap data primer dan sekunder, kajian ini mendapati kebanyakan negeri di Malaysia tidak membenarkan penolakan KP dan KSH daripada PK, kecuali empat buah negeri iaitu Perlis, Pulau Pinang, Sabah dan Sarawak. Sabah dan Sarawak hanya membenarkan penolakan KP daripada PK, manakala Perlis dan Pulau Pinang bukan sahaja membenarkan penolakan KP, malah turut menolak KSH daripada PK. Meskipun berbeza dengan negeri-negeri lain, amalan perakaunan zakat padi di keempat-empat buah negeri ini masih selari dengan pandangan fuqaha’.

  2. TRADE instructional materials for SARA/OSHA training. Volume 2, Managers and supervisors training

    Energy Technology Data Exchange (ETDEWEB)

    1989-03-01

    This document provides instructional materials for an eight-hour training course for managers and supervisors of hazardous waste sites. It is one of three volumes of course materials TRADE is preparing to help DOE contractor training staff comply with 29 CFR 1910.120, the Occupational Health and Safety Administration (OSHA) rule that implements Title I of the Superfund Amendments and Reauthorization Act (SARA) of 1986. OSHA`s final rule for hazardous waste operators was published in the Federal Register of March 6, 1989 (54 FR 9294). Combined with the materials in Volumes I and III and with appropriate site-specific information, these materials will help DOE contractors to meet the requirements of 1910.120 (e) that ``on-site management and supervisors directly responsible for, or who supervise employees engaged in, hazardous waste operations`` receive the same initial training as that of the employees they supervise and at least eight additional hours of specialized training in managing hazardous waste operations.

  3. La difesa della donna ebrea: Sara Copio Sullam e Debora Ascarelli

    Directory of Open Access Journals (Sweden)

    Umberto Fortis

    2014-04-01

    Full Text Available Sara Copio Sullam and Debora Ascarelli, the best-known Jewish women poets of the age of the Italian ghetto, have often been studied with a focus on the distinctive features of their writing: the former as a translator of sacred texts, the latter as the author of original verses, sometimes written as a risposta per le rime (reply through rhymes or in defence of her orthodoxy. They share, however, a common theme, which has often been neglected: the defence of the Jewish woman, which is overt in some of Copio’s sonnets and prose, whereas it has not yet been properly pointed out in some of Ascarelli’s verses. This paper aims at bringing this theme to the fore not only in Copio, through a rereading of some passages of her Manifesto, but also in Debora Ascarelli, through an analysis of her few original verses. These hendecasyllables certainly reflect the Petrarchan and classicistic atmosphere of the late 16th century in Rome, but they are far from the mainstream modes of women’s poetry of the age. They allow us, therefore, to highlight, besides the differences, the similarities between the two poetesses; their commitment, in the late 16th and early 17th century, to the intellectual and moral defence of the Jewish woman, in a context of general depreciation of women, but also in the background of the claim to the “nobility and excellence of women”.

  4. Reading Sara Pujol Russell’s Poetry of Contemplation and Connection

    Directory of Open Access Journals (Sweden)

    Anita M. Hart

    2012-06-01

    Full Text Available Sara Pujol Russell’s poetry captures a process of expanding consciousness and personal renewal. Through contemplation and attention to nature, the poet-speaker in her works generates a sense of connection that moves her beyond daily concerns. Pujol’s poetry is both metaphysical and also different in that it resists easy classification and is not representative of mainstream trends. This essay approaches the distinctiveness of Pujol’s work by studying selected poems from her third book of poetry in Spanish, Para decir sí a la carencia, sí a la naranja, al azafrán en el pan (2004 ‘To Say Yes to Lack, Yes to the Orange, to the Saffron in the Bread.’ Incorporating philosopher María Zambrano’s thoughts on contemplation, it shows Pujol’s poet-speaker establishing a connection with nature and spirit, experiencing a heightened consciousness, and searching for expression. The poetic language is characterized by vision, intimacy, enigma, and contradiction. In its subjective, intuitive way, Pujol’s work reveals the poet-speaker’s winding path of discovery and challenges the reader to look closely inside and outside in engaging life’s mysteries.

  5. Single-electron detection and spectroscopy via relativistic cyclotron radiation

    Energy Technology Data Exchange (ETDEWEB)

    Asner, David M.; Bradley, Rich; De Viveiros Souza Filho, Luiz A.; Doe, Peter J.; Fernandes, Justin L.; Fertl, M.; Finn, Erin C.; Formaggio, Joseph; Furse, Daniel L.; Jones, Anthony M.; Kofron, Jared N.; LaRoque, Benjamin; Leber, Michelle; MCBride, Lisa; Miller, M. L.; Mohanmurthy, Prajwal T.; Monreal, Ben; Oblath, Noah S.; Robertson, R. G. H.; Rosenberg, Leslie; Rybka, Gray; Rysewyk, Devyn M.; Sternberg, Michael G.; Tedeschi, Jonathan R.; Thummler, Thomas; VanDevender, Brent A.; Woods, N. L.

    2015-04-01

    It has been understood since 1897 that accelerating charges should emit electromagnetic radiation. Cyclotron radiation, the particular form of radiation emitted by an electron orbiting in a magnetic field, was first derived in 1904. Despite the simplicity of this concept, and the enormous utility of electron spectroscopy in nuclear and particle physics, single-electron cyclotron radiation has never been observed directly. Here we demonstrate single-electron detection in a novel radiofrequency spectrometer. We observe the cyclotron radiation emitted by individual electrons that are produced with mildly-relativistic energies by a gaseous radioactive source and are magnetically trapped. The relativistic shift in the cyclotron frequency permits a precise electron energy measurement. Precise beta electron spectroscopy from gaseous radiation sources is a key technique in modern efforts to measure the neutrino mass via the tritium decay endpoint, and this work is a proof-of-concept for future neutrino mass experiments using this technique.

  6. Neutron field inside a PET Cyclotron vault room

    Energy Technology Data Exchange (ETDEWEB)

    Vega C, H.R. [UAZ, C. Cipres 10, 98068 Zacatecas (Mexico); Mendez, R. [CIEMAT, Ave. Complutense 22, 28040 Madrid (Spain); Iniguez, M.P. [Universidad de Valladolid, Po Prado de la Magdalena s/n, 47011 Valladolid (Spain); Climent, J.M.; Penuelas, I. [Servicio de Medicina Nuclear de la Clinica Universitaria de Navarra, Pamplona (Spain); Barquero, R. [Hospital Universitario Rio Hortega, Valladolid (Spain)]. e-mail: fermineutron@yahoo.com

    2006-07-01

    The neutron field around a Positron Emission Tomography cyclotron was investigated during {sup 18} F radioisotope production with an 18 MeV proton beam. In this study the Ion Beam Application cyclotron, model Cyclone 18/9, was utilized. Measurements were carried out with a Bonner sphere neutron spectrometer with pairs of thermoluminescent dosemeters (TLD600 and TLD700) as thermal neutron detector. The TLDs readouts were utilized to unfold the neutron spectra at three different positions inside the cyclotron's vault room. With the spectra the Ambient dose equivalent was calculated. Neutron spectra unfolding were performed with the BUNKIUT code and the UTA4 response matrix. Neutron spectra were also determined by Monte Carlo calculations using a detailed model of cyclotron and vault room. (Author)

  7. Vacuum Control Systems of the Cyclotrons in VECC, Kolkata

    Science.gov (United States)

    Roy, Anindya; Akhtar, Javed; Yadav, R. C.; Bhole, R. B.; Pal, Sarbajit; Sarkar, D.; Bhandari, R. K.

    2012-11-01

    VECC has undertaken the modernization of the K-130 Room Temperature Cyclotron (RTC) (operational since 1978) and commissioning of K-500 Superconducting Cyclotron (SCC) at present. The control system of RTC vacuum system has been upgraded to Programmable Logic Controller (PLC) based automated system from relay based manual system. A distributed PLC based system is under installation for SCC vacuum system. The requirement of high vacuum in both the cyclotrons (1×10-6 mbar for RTC and 5 × 10-8 mbar SCC) imposes the reliable local and remote operation of all vacuum components and instrumentation. The design and development of the vacuum control system of two cyclotrons using the Experimental Physics and Industrial Control System (EPICS) distributed real-time software tools are presented.

  8. Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 23

    Energy Technology Data Exchange (ETDEWEB)

    1967-10-09

    Progress is reported in the design, installation of various components of the cyclotron, including coils, magnets, rf system, and vacuum system. Also reported are measurements on magnets and rf components. (LEW)

  9. Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 20

    Energy Technology Data Exchange (ETDEWEB)

    1967-06-30

    Progress is reported in the fabrication and testing of cyclotron components, including magnet system and rf system components. Work on vacuum components and instrumentation and control equipment is also reported. (LEW)

  10. Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 32

    Energy Technology Data Exchange (ETDEWEB)

    1968-06-28

    Completion of magnet tests, followed by completion of installation of major cyclotron components, are reported. Intermediate level power tests of the rf system are also reported. Design and fabrication of the control system are reported to be under way. (LEW)

  11. Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 26

    Energy Technology Data Exchange (ETDEWEB)

    1968-01-17

    Progress is reported in the fabrication, installation, and testing of cyclotron components, including magnets and coils, rf components, vacuum and control equipment. Also reported are magnet and rf component measurements. (LEW)

  12. Relativistic Cyclotron Resonance Shape in Magnetic Bottle Geonium

    National Research Council Canada - National Science Library

    Hans Dehmelt; Richard Mittleman; Yuan Liu

    1988-01-01

    The thermally excited axial oscillation of the electron through the weak magnetic bottle needed for the continuous Stern-Gerlach effect modulates the cyclotron frequency and produces a characteristic...

  13. Cryogenic system for VECC K500 superconducting cyclotron

    CERN Document Server

    Pal, G; Bhattacharyya, T K; Bhandari, R K

    2009-01-01

    VEC Centre, Kolkata in India is at an advanced stage of commissioning a K500 superconducting cyclotron. The superconducting coil of the magnet for cyclotron is cooled by liquid helium. Three liquid helium cooled cryopanels, placed inside the Dees of the radiofrequency system, maintain the vacuum in the acceleration region of the superconducting cyclotron. The cryogenic system for magnet for cyclotron has been tested by cooling the coil and energizing the magnet. The cryogenic system for cryopanels has also been tested. Heater and temperature sensor were placed on the liquid helium cold head for cryopanel. The temperature of the cold head was observed to be below 20 K upto a heat load of 11.7 watt.

  14. Design of 10 MeV cyclotron accelerator

    Directory of Open Access Journals (Sweden)

    R Solhju

    2015-09-01

    Full Text Available Design and construction of 10MeV cyclotron has been started at Amirkabir University of Technology since 2012. So far, the conceptual and detail engineering design phases have been finalized. The main purpose of this baby cyclotron is to generate proton beam for the production of PET radioisotopes. The cyclotron consists of magnet, cavity, ion source, RF and LLRF system, vacuum system, cooling system, power amplifiers and power supplies system. In this paper, a brief of design principles for all the parts of cyclotron and their final simulation results is presented. It should be noted that these simulations have been performed and optimized by the most accurate softwares such as TOSCA, ANSYS, HFSS, SolidWorks and CST. Also, the manufacturing feasibility of all the parts is performed and their dimensions and parameters are synchronized with manufacturing standards

  15. A new way to measure the electron cyclotron frequency

    Science.gov (United States)

    Palmer, F. L.

    1993-03-01

    A method is described for using spin flips to measure the 0 to 1 cyclotron transition frequency of a single electron in a Penning trap. Detection can be accomplished with magnetic bottles of 10 T/m2 or less, thereby greatly reducing the thermal broadening of the cyclotron line. This method complements a recently published technique for measuring the anomaly frequency, making a more precise measurement of the electron anomaly ratio possible.

  16. Ion-Beam-Excited Electrostatic Ion Cyclotron Waves

    DEFF Research Database (Denmark)

    Michelsen, Poul; Pécseli, Hans; Juul Rasmussen, Jens

    1976-01-01

    Self-excited electrostatic ion cyclotron waves were observed in an ion-beam-plasma system produced in a DP-operated Q-machine. The frequency of the waves showed the theoretically predicted variation with the magnetic field.......Self-excited electrostatic ion cyclotron waves were observed in an ion-beam-plasma system produced in a DP-operated Q-machine. The frequency of the waves showed the theoretically predicted variation with the magnetic field....

  17. PET computer programs for use with the 88-inch cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Gough, R.A.; Chlosta, L.

    1981-06-01

    This report describes in detail several offline programs written for the PET computer which provide an efficient data management system to assist with the operation of the 88-Inch Cyclotron. This function includes the capability to predict settings for all cyclotron and beam line parameters for all beams within the present operating domain of the facility. The establishment of a data base for operational records is also described from which various aspects of the operating history can be projected.

  18. SarA is a repressor of hla (alpha-hemolysin) transcription in Staphylococcus aureus: its apparent role as an activator of hla in the prototype strain NCTC 8325 depends on reduced expression of sarS.

    Science.gov (United States)

    Oscarsson, Jan; Kanth, Anna; Tegmark-Wisell, Karin; Arvidson, Staffan

    2006-12-01

    In most Staphylococcus aureus strains, inactivation of sarA increases hla transcription, indicating that sarA is a repressor. However, in S. aureus NCTC 8325 and its derivatives, used for most studies of hla regulation, inactivation of sarA resulted in decreased hla transcription. The disparate phenotype of strain NCTC 8325 seems to be associated with its rsbU mutation, which leads to sigma(B) deficiency. This has now been verified by the demonstration that sarA repressed hla transcription in an rsbU+ derivative of strain 8325-4 (SH1000). That sarA could act as a repressor of hla in an 8325-4 background was confirmed by the observation that inactivation of sarA in an agr sarS rot triple mutant dramatically increased hla transcription to wild-type levels. However, the apparent role of sarA as an activator of hla in 8325-4 was not a result of the rsbU mutation alone, as inactivation of sarA in another rsbU mutant, strain V8, led to increased hla transcription. Northern blot analysis revealed much higher levels of sarS mRNA in strain V8 than in 8325-4, which was likely due to the mutation in the sarS activator, tcaR, in 8325-4, which was not found in strain V8. On the other hand, the relative increase in sarS transcription upon the inactivation of sarA was 15-fold higher in 8325-4 than in strain V8. Because of this, inactivation of sarA in 8325-4 means a net increase in repressor activity, whereas in strain V8, inactivation of sarA means a net decrease in repressor activity and, therefore, enhanced hla transcription.

  19. Hepatic TLR4 signaling is activated by LPS from digestive tract during SARA, and epigenetic mechanisms contribute to enforced TLR4 expression

    Science.gov (United States)

    Chang, Guangjun; Zhuang, Su; Seyfert, Hans-Martin; Zhang, Kai; Xu, Tianle; Jin, Di; Guo, Junfei; Shen, Xiangzhen

    2015-01-01

    Subacute ruminal acidosis (SARA) is known to trigger a systemic inflammatory response that is possibly caused by the translocationof lipopolysaccharides (LPS) from the gastrointestinal tract into the bloodstream. The aim of this study is to investigate this causal relationship between the increases of circulating LPS and liver inflammation. Here we found that SARA goats exhibited significantly increased LPS concentrations in both the rumen and portal vein. The livers of these goats exhibited increased mRNA concentrations of pro-inflammatory genes that indicated inflammation. Meanwhile, the occurrence of liver inflammation was further validated by the enhanced protein expression of those cytokines in the livers of SARA goats. These increased expressions of detected pro-inflammatory genes were likely mediated by enforced TLR4 signaling because SARA increased the concentrations of TLR4 mRNA and protein in the liver and the abundance of both the NF-kB-p65 factor and its active phosphorylated variant. We also verified that the enhanced TLR4 expression was accompanied by chromatin decompaction and demethylation of the proximal TLR4 promoter. Hence, epigenetic mechanisms are involved in the enforced expression of immune genes during SARA, and these findings open innovative routes for interventions via the modulation of these epigenetic mechanisms. PMID:26498350

  20. Impact of subacute ruminal acidosis (SARA) adaptation and recovery on the density and diversity of bacteria in the rumen of dairy cows.

    Science.gov (United States)

    Hook, Sarah E; Steele, Michael A; Northwood, Korinne S; Dijkstra, Jan; France, James; Wright, André-Denis G; McBride, Brian W

    2011-11-01

    Subacute ruminal acidosis (SARA) is characterized by ruminal pH depression and microbial perturbation. The impact of SARA adaptation and recovery on rumen bacterial density and diversity was investigated following high-grain feeding. Four ruminally cannulated dairy cows were fed a hay diet, transitioned to a 65% grain diet for 3 weeks, and returned to the hay diet for 3 weeks. Rumen fluid, rumen solids, and feces were sampled during weeks 0 (hay), 1 and 3 (high grain), and 4 and 6 (hay). SARA was diagnosed during week 1, with a pH below 5.6 for 4.6±1.4 h. Bacterial density was significantly lower in the rumen solids with high grain (P=0.047). Rumen fluid clone libraries from weeks 0, 3, and 6 were assessed at the 98% level and 154 operational taxonomic units were resolved. Week 3 diversity significantly differed from week 0, and community structure differed from weeks 0 and 6 (P<0.0001). Clones belonging to the phylum Firmicutes predominated. Compared with the hay diet, the high-grain diet contained clones from Selenomonas ruminantium and Succiniclasticum ruminis, but lacked Eubacterium spp. SARA adaptation was found to significantly alter bacterial density, diversity, and community structure, warranting further investigation into the role bacteria play in SARA adaptation. © 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.

  1. Regulation of biofilm formation by sigma B is a common mechanism in Staphylococcus epidermidis and is not mediated by transcriptional regulation of sarA.

    Science.gov (United States)

    Jäger, Sebastian; Jonas, Beate; Pfanzelt, Dorothea; Horstkotte, Matthias A; Rohde, Holger; Mack, Dietrich; Knobloch, Johannes K-M

    2009-09-01

    Biofilm formation is a major pathogenetic factor of Staphylococcus epidermidis. In S. epidermidis the alternative sigma factor sigma B was identified to regulate biofilm formation in S. epidermidis 1457. In S. aureus sigma B dependent regulation plays a minor role, whereas sarA (Staphylococcus accessory regulator) is an essential regulator. Therefore, we investigated the impact of sigma B on sarA transcription and biofilm formation in three independent S. epidermidis isolates. Mutants with dysfunctional sigma B displayed a strongly reduced biofilm formation, whereas in mutants with constitutive sigma B activity biofilm formation was increased. Transcriptional analysis revealed that icaA transcription was down-regulated in all sigma B negative mutants while icaR transcription was up-regulated. However, transcriptional differences varied between individual strains, indicating that additional sigma B-dependent regulators are involved in biofilm expression. Interestingly, despite the presence of a sigma B promoter beside two sigma A promoters no differences, or only minor ones, were observed in sarA transcription, indicating that sigma B-dependent sarA transcript has no influence on the phenotypic changes. The data observed in independent clinical S. epidermidis isolates suggests that, in contrast to S. aureus, regulation of biofilm formation by sigma B is a general feature in S. epidermidis. Additionally, we were able to demonstrate that the sarA- dependent regulation is not involved in this regulatory pathway.

  2. Ion source and injection line for high intensity medical cyclotron.

    Science.gov (United States)

    Jia, XianLu; Guan, Fengping; Yao, Hongjuan; Zhang, TianJue; Yang, Jianjun; Song, Guofang; Ge, Tao; Qin, Jiuchang

    2014-02-01

    A 14 MeV high intensity compact cyclotron, CYCIAE-14, was built at China Institute of Atomic Energy (CIAE). An injection system based on the external H- ion source was used on CYCIAE-14 so as to provide high intensity beam, while most positron emission tomography cyclotrons adopt internal ion source. A beam intensity of 100 μA/14 MeV was extracted from the cyclotron with a small multi-cusp H- ion source (CIAE-CH-I type) and a short injection line, which the H- ion source of 3 mA/25 keV H- beam with emittance of 0.3π mm mrad and the injection line of with only 1.2 m from the extraction of ion source to the medial plane of the cyclotron. To increase the extracted beam intensity of the cyclotron, a new ion source (CIAE-CH-II type) of 9.1 mA was used, with maximum of 500 μA was achieved from the cyclotron. The design and test results of the ion source and injection line optimized for high intensity acceleration will be given in this paper.

  3. Electromagnetic cyclotron waves near the proton cyclotron frequency in the solar wind

    Science.gov (United States)

    Jian, Lan K.; Boardsen, Scott; Moya, Pablo; Stevens, Michael; Alexander, Robert; Vinas, Adolfo

    2015-04-01

    Strong narrow-band electromagnetic waves around the proton cyclotron frequency (fpc) have been found sporadically in the solar wind from 0.3 to 0.7 AU during MESSENGER spacecraft’s cruise phase. These waves are transverse and circularly polarized, and they propagate in directions quasi-parallel to the magnetic field. The wave power decreases quadratically with heliocentric distance, faster than the trend if assuming the conservation of Poynting flux for wave packets, suggesting there is energy dissipation from the waves, which could contribute to the heating and acceleration of solar wind plasma. Although the wave frequency is a few times of fpc in the spacecraft frame, it is a fraction of fpc in the solar wind plasma frame after removing the Doppler shift effect. In this frequency range, the waves can be left-hand (LH) polarized ion cyclotron waves or right-hand (RH) polarized magnetosonic waves. Because the waves are LH or RH polarized in the spacecraft frame with otherwise nearly identical characteristics, they could be due to Doppler shift of a same type of waves or a mixture of waves with intrinsically different polarizations. Through the assistance of audification, we have studied the long-lasting wave events in 2005 using high-cadence magnetic field data from the Wind mission. Statistically, in contrast with general solar wind, the protons at these waves are distributed closer to the proton instability thresholds, while the alpha particles at these waves are distributed further away from the alpha instability thresholds. For selected events of extensive waves, the ion distribution is analyzed in detail. A mixture of temperature anisotropies for core protons, beam protons, and alpha particles, as well as proton beam drift are often found in such events. We conduct linear wave dispersion analysis using these ion moments to examine whether these waves can be explained by the local generation of kinetic instabilities such as the LH ion cyclotron, the RH

  4. Women Empowerment in the Realms of Institutionalized Religion and Patriarchy: El Saadawi’s Firdaus and Yezierska’s Sara as Examples

    Directory of Open Access Journals (Sweden)

    Abdullah K. Shehabat

    2016-09-01

    Full Text Available This paper explains how the two protagonists, Firdaus and Sara, successfully paved their own ways in search of self-liberation despite the authoritarian patriarchy and institutionalized religions that plagued them. El Saadawi's Woman at Point Zero and Yezierska’s Bread Givers represent the fruitful struggle these protagonists experienced as they come to forge an identity and be themselves. The paper argues that the protagonists manage to free themselves, establish their own spiritual homes at their own homes and assert the potentials of their femininity despite their endings. Empowered by the powers of reading, strong will and meticulous work, the protagonists were able to realize their own material independence and achieve their lifelong ambitions. However, through Firdaus' and Sara's journeys of breaking their silence, they were subject to different patterns of self-annihilation. While Firdaus was sentenced to death for killing a pimp, Sara embraced living under the hegemony of an authoritarian husband.

  5. Correlation electron cyclotron emission diagnostic in TCV

    Science.gov (United States)

    Fontana, M.; Porte, L.; Molina Cabrera, P.

    2017-08-01

    The correlation electron cyclotron emission diagnostic of tokamak à configuration variable has recently been upgraded. It now has the choice of three lines of sight: two horizontal lines placed on the low field side of the vessel, perpendicular to the magnetic field, and a dual-axis steerable antenna. The polarization of the radiation collected by the latter can be rotated using a universal polarizer situated in the transmission line. This line is also shared with a reflectometry system, allowing simultaneous measurements of temperature and density fluctuations in the same plasma volumes. When using this line, it is possible to choose between two dedicated front ends characterized by different local oscillator frequencies, adding flexibility in the choice of the plasma region to be studied. The intermediate frequency section is now equipped with six frequency tunable YIG filters allowing the study of turbulence properties in a wide range of radial positions. When studying fluctuations over the whole video bandwidth, the minimum detectable fluctuation level is δ Te/Te˜0.5 % . The new system has been used to measure electron temperature fluctuations over a large fraction of the plasma profiles in a series of plasmas with triangularity varying from 0.6 to -0.6 but comparable collisionality profiles.

  6. DETERMINACIÓN DE LAS FRACCIONES SARA DE ASFALTOS COLOMBIANOS ENVEJECIDOS AL MEDIO AMBIENTE EMPLEANDO CROMATOGRAFÍA LÍQUIDA EN COLUMNA DETERMINAÇÃO DAS FRAÇÕES SARA DE ASFALTOS COLOMBIANOS ENVELHECIDOS AO MÉDIO AMBIENTE EMPREGANDO CROMATOGRAFIA LÍQUIDA EM COLUNA DETERMINATION OF SARA FRACTIONS OF ENVIRONMENTALLY AGED COLOMBIAN ASPHALTS USING LIQUID CHROMATOGRAPHY COLUMN

    Directory of Open Access Journals (Sweden)

    Fredy Alberto Reyes

    2012-06-01

    Full Text Available En este artículo presentamos un método basado en cromatografía líquida en columna para cuantificar la composición química de los cementos asfálticos fabricados en Colombia, sometidos al medio ambiente, mediante la determinación de las fracciones SARA. El método fue aplicado sobre películas de asfalto 60/70 y 80/100 para determinar los cambios en la composición química del material luego de ser expuesto durante 12 meses a las condiciones de intemperie de la ciudad de Bogotá; los ensayos de SARA fueron efectuados para el asfalto original a 1, 3, 6, 9 y 12 meses respectivamente. Los fraccionamientos SARA evidenciaron que el envejecimiento produjo una disminución de la fracción de aromáticos y un incremento en la de asfaltenos respecto al asfalto no envejecido. La disminución de los compuestos aromáticos y de resinas pudo ser responsable del endurecimiento observado en los asfaltos, que presentaron una consistencia dura y quebradiza, lo que está de acuerdo con la obtención de índices coloidales elevados. El método empleado permitió establecer correlaciones entre la composición química del asfalto y sus propiedades mecánicas.Neste artigo apresentamos um método baseado em cromatografia líquida em coluna para quantificar a composição química dos cimentos asfálticos fabricados em Colômbia, submetidos ao médio ambiente, mediante a determinação das frações SARA. O método foi aplicado sobre películas de asfalto 60/70 e 80/100 para determinar as mudanças na composição química do material depois de ser exposto durante 12 meses às condições de intempérie da cidade de Bogotá; os ensaios de SARA foram efetuados para o asfalto original a 1, 3, 6, 9 e 12 meses respectivamente. Os fraccionamentos SARA evidenciaram que o envelhecimento produziu uma diminuição da fração de aromáticos e um incremento na de asfaltenos com respeito ao asfalto não envelhecido. A diminuição dos compostos aromáticos e de resinas p

  7. Inverse ion-cyclotron damping and excitation of multiharmonic ion-cyclotron waves in the northern magnetospheric cusp

    Science.gov (United States)

    Slapak, Rikard; Gunell, Herbert; Hamrin, Maria

    2017-04-01

    We have investigated a case of inverse ion-cyclotron damping taking place in the northern terrestrial magnetospheric cusp, exciting waves at the ion-cyclotron frequency and its harmonics. Magnetosheath influx in the cusps and the effect of convection and magnetic mirroring give rise to parallel velocity shears, dvallel/dx\\perp, often associated with instabilities in the plasma and corresponding ion-cyclotron waves, whose evolution is described by a damping factor. This damping factor depends on, for example, the wave numbers and the velocity shear itself and can under certain conditions be negative, hence describing inverse damping (or wave growth). However, an additional required condition for inverse ion-cyclotron damping is a velocity shear in the magnetic field-aligned ion-bulk flow, and this condition is only met for magnetosheath influx in the northern cusp, as oppose to the southern cusp. The ion-cyclotron waves are primarily seen as peaks in the magnetic-field spectral densities, as presented by Slapak et al., [GRL (2016), doi:10.1002/2016GL071680]. The corresponding peaks in the electric-field spectral densities are not as profound, suggesting a background electric field noise or other processes of wave generation causing the electric spectral densities to smoothen out more compared to the magnetic counterpart. We note that some ion-cyclotron wave activity is present in a few similar shear events in the southern cusp, which indicates that other mechanisms generating ion-cyclotron waves may also be present during such conditions.

  8. Design of RF system for CYCIAE-230 superconducting cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Yin, Zhiguo, E-mail: bitbearAT@hotmail.com; Ji, Bin; Fu, Xiaoliang; Cao, Xuelong; Zhao, Zhenlu; Zhang, Tinajue

    2017-05-11

    The CYCIAE230 is a low-current, compact superconducting cyclotron designed for proton therapy. The Radio Frequency system consists of four RF cavities and applies second harmonic to accelerate beams. The driving power for the cavity system is estimated to be approximately 150 kW. The LLRF controller is a self-made device developed and tested at low power using a small-scale cavity model. In this paper, the resonator systems of an S.C. cyclotron in history are reviewed. Contrary to those RF systems, the cavities of the CYCIAE230 cyclotron connect two opposite dees. Two high-power RF windows are included in the system. Each window carries approximately 75 kW RF power from the driver to the cavities. Thus, the RF system for the CY-CIAE230 cyclotron is operated in driven push–pull mode. The two-way amplifier-coupler-cavity systems are operated with approximately the same amount of RF power but 180° out of phase compared with each other. The design, as well as the technical advantage and limitations of this operating mode, of the CYCIAE230 cyclotron RF system is analyzed.

  9. Relativistic Cyclotron Resonance Shape in Magnetic Bottle Geonium

    Science.gov (United States)

    Dehmelt, Hans; Mittleman, Richard; Liu, Yuan

    1988-10-01

    The thermally excited axial oscillation of the electron through the weak magnetic bottle needed for the continuous Stern-Gerlach effect modulates the cyclotron frequency and produces a characteristic ≈ 12-kHz-wide vertical rise-exponential decline line shape of the cyclotron resonance. At the same time the relativistic mass shift decreases the frequency by ≈ 200 Hz per cyclotron motion quantum level n. Nevertheless, our analysis of the complex line shape shows that it should be possible to produce an abrupt rise in the cyclotron quantum number n from 0 to ≈ 20 over a small fraction of 200 Hz, when the 160-GHz microwave drive approaches the n = 0 → 1 transition, and a jump of 14 levels over a frequency increment of 200 Hz has already been observed in preliminary work. This realizes an earlier proposal to generate a very sharp cyclotron resonance feature by quasithermal excitation with a square noise band and should provide a way to detect spin flips when a weak bottle is used to reduce the broadening of the g - 2 resonance by a factor of 20.

  10. Design of RF system for CYCIAE-230 superconducting cyclotron

    Science.gov (United States)

    Yin, Zhiguo; Ji, Bin; Fu, Xiaoliang; Cao, Xuelong; Zhao, Zhenlu; Zhang, Tinajue

    2017-05-01

    The CYCIAE230 is a low-current, compact superconducting cyclotron designed for proton therapy. The Radio Frequency system consists of four RF cavities and applies second harmonic to accelerate beams. The driving power for the cavity system is estimated to be approximately 150 kW. The LLRF controller is a self-made device developed and tested at low power using a small-scale cavity model. In this paper, the resonator systems of an S.C. cyclotron in history are reviewed. Contrary to those RF systems, the cavities of the CYCIAE230 cyclotron connect two opposite dees. Two high-power RF windows are included in the system. Each window carries approximately 75 kW RF power from the driver to the cavities. Thus, the RF system for the CY-CIAE230 cyclotron is operated in driven push-pull mode. The two-way amplifier-coupler-cavity systems are operated with approximately the same amount of RF power but 180° out of phase compared with each other. The design, as well as the technical advantage and limitations of this operating mode, of the CYCIAE230 cyclotron RF system is analyzed.

  11. Risk assessment of 30 MeV cyclotron facilities

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Gyo Seong; Lee, Jin Woo [Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of); Kim, Chong Yeal [Dept. of Radiation Science and Technology, Chonbuk National University, Jeonju (Korea, Republic of)

    2017-03-15

    A cyclotron is a kind of particle accelerator that produces a beam of charged particles for the production of medical, industrial, and research radioisotopes. More than 30 cyclotrons are operated in Korea to produce 18F, an FDG synthesis at hospitals. A 30-MeV cyclotron was installed at ARTI (Advanced Radiation Technology Institute, KAERI) mainly for research regarding isotope production. In this study, we analyze and estimate the items of risk such as the problems in the main components of the cyclotron, the loss of radioactive materials, the leakage of coolant, and the malfunction of utilities, fres and earthquakes. To estimate the occurrence frequency in an accident risk assessment, five levels, i.e., Almost certain, Likely, Possible, Unlikely, and Rare, are applied. The accident consequence level is classified under four grades based on the annual permissible dose for radiation workers and the public in the nuclear safety law. The analysis of the accident effect is focused on the radioactive contamination caused by radioisotope leakage and radioactive material leakage of a ventilation filter due to a free. To analyze the risks, Occupation Safety and Health Acts is applied. In addition, action plans against an accident were prepared after a deep discussion among relevant researchers. In this acts, we will search for hazard and introduce the risk assessment for the research 30-MeV cyclotron facilities of ARTI.

  12. SARA South Observations and Analysis of the Solar Type, Totally Eclipsing, Over Contact Binary, PY Aquarii

    Science.gov (United States)

    Chamberlain, Heather; Samec, Ronald G.; Caton, Daniel Bruce; Van Hamme, Walter

    2018-01-01

    PY Aqr (GSC 05191-00853) is a solar Type (T ~ 5750K) eclipsing binary. It was observed in July to October, 2017 at Cerro Tololo in remote mode with the 0.6-m SARA South reflector. Two times of minimum light were calculated from our present observations, a primary and a secondary eclipse:HJD Min I = 2457951.7762±0.0006 HJD Min II = 2458019.5295±00.0003. Both weighted as 1.0.In addition, four timings were determined from online data given in IBVS 5600 and five observations at minima were determined from archived All Sky Automated Survey Data:HJD Min I = 2452908.3165, 2452912.33612 HJD Min II = 2452877.5621, 2452913.34465. All weighted as 0.5.ASAS Observations at minima: 2452094.688, 2453478.882, 2453266.576, 2452093.685 and 54729.600. Each weighted as 0.10The following linear and quadratic ephemerides were determined from all available times of minimum light:JD Hel Min I=2452951.7443±0.0008d + 0.402093441±0.000000099 X E {1} JD Hel Min I=2452951.7439±0.0007d + 0.4020912±0.0000007 X E +0.00000000018 ± 0.00000000006 X E2 {2}A BVRI Bessell filtered simultaneous Wilson-Devinney Program (W-D) solution reveals that the system has a mass ratio of ~0.34 and a component temperature difference of only ~40 K. One low luminosity (Tfact ~ 0.94, ~66 degree radius) large cool region of spots was iterated on the primary component in the WD Synthetic Light Curve computations. It appears in the Southern Hemisphere (colatitude 155 degrees). The Roche Lobe fill-out of the binary is ~17%. The inclination is ~86 degrees. An eclipse duration of ~10 minutes was determined for the primary eclipse and the light curve solution. Additional and more detailed information is given in this report.

  13. 75 FR 48939 - National Superconducting Cyclotron Laboratory of Michigan State University; Notice of Decision on...

    Science.gov (United States)

    2010-08-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF COMMERCE International Trade Administration National Superconducting Cyclotron Laboratory of Michigan State University...., NW., Washington, DC. Docket Number: 10-043. Applicant: National Superconducting Cyclotron Laboratory...

  14. Development of a fast scintillator based beam phase measurement system for compact superconducting cyclotrons

    Energy Technology Data Exchange (ETDEWEB)

    Bhattacharjee, Tanushyam; Kanti Dey, Malay; Dhara, Partha; Roy, Suvodeep; Debnath, Jayanta; Balakrishna Bhole, Rajendra; Dutta, Atanu; Pradhan, Jedidiah; Pal, Sarbajit; Pal, Gautam; Roy, Amitava; Chakrabarti, Alok [Variable Energy Cyclotron Centre, 1/AF Bidhannagar, Kolkata 700064 (India)

    2013-05-15

    In an isochronous cyclotron, measurements of central phase of the ion beam with respect to rf and the phase width provide a way to tune the cyclotron for maximum energy gain per turn and efficient extraction. We report here the development of a phase measurement system and the measurements carried out at the Variable Energy Cyclotron Centre's (VECC's) K= 500 superconducting cyclotron. The technique comprises detecting prompt {gamma}-rays resulting from the interaction of cyclotron ion beam with an aluminium target mounted on a radial probe in coincidence with cyclotron rf. An assembly comprising a fast scintillator and a liquid light-guide inserted inside the cyclotron was used to detect the {gamma}-rays and to transfer the light signal outside the cyclotron where a matching photo-multiplier tube was used for light to electrical signal conversion. The typical beam intensity for this measurement was a few times 10{sup 11} pps.

  15. Calibration of the simulation model of the VINCY cyclotron magnet

    Directory of Open Access Journals (Sweden)

    Ćirković Saša

    2002-01-01

    Full Text Available The MERMAID program will be used to isochronise the nominal magnetic field of the VINCY Cyclotron. This program simulates the response, i. e. calculates the magnetic field, of a previously defined model of a magnet. The accuracy of 3D field calculation depends on the density of the grid points in the simulation model grid. The size of the VINCY Cyclotron and the maximum number of grid points in the XY plane limited by MERMAID define the maximumobtainable accuracy of field calculations. Comparisons of the field simulated with maximum obtainable accuracy with the magnetic field measured in the first phase of the VINCY Cyclotron magnetic field measurements campaign has shown that the difference between these two fields is not as small as required. Further decrease of the difference between these fields is obtained by the simulation model calibration, i. e. by adjusting the current through the main coils in the simulation model.

  16. Cyclotron instabilities driven by temperature anisotropy in the solar wind

    Science.gov (United States)

    Noreen, N.; Yoon, P. H.; Zaheer, S.

    2017-10-01

    Kinetic plasma instabilities are important for regulating the temperature anisotropies of electrons and ions in solar wind. For the low beta regime, it is known that electromagnetic ion/electron cyclotron instabilities are important, but in the literature these unstable modes are discussed under the assumption of parallel propagation. The present paper extends the analysis to two (or with cylindrical symmetry, three) dimensions. The analysis is further extended to include quasilinear description with the assumption of the bi-Maxwellian velocity distribution function. Such an analysis lays the foundation for an eventual study in which cyclotron instabilities as well as obliquely propagating unstable modes such as the mirror instability are simultaneously taken into account. The present paper first lays down the basis for such future efforts in which the two- or three dimensional linear and quasilinear theories of cyclotron instabilities in the low beta regime are formulated.

  17. Calibration of the simulation model of the Vincy cyclotron magnet

    CERN Document Server

    Cirkovic, S; Vorozhtsov, A S; Vorozhtsov, S B

    2002-01-01

    The MERMAID program will be used to isochronise the nominal magnetic field of the VINCY Cyclotron. This program simulates the response, i. e. calculates the magnetic field, of a previously defined model of a magnet. The accuracy of 3D field calculation depends on the density of the grid points in the simulation model grid. The size of the VINCY Cyclotron and the maximum number of grid points in the XY plane limited by MERMAID define the maximum obtainable accuracy of field calculations. Comparisons of the field simulated with maximum obtainable accuracy with the magnetic field measured in the first phase of the VINCY Cyclotron magnetic field measurements campaign has shown that the difference between these two fields is not as small as required. Further decrease of the difference between these fields is obtained by the simulation model calibration, i. e. by adjusting the current through the main coils in the simulation model.

  18. Distribution of thermal neutron flux around a PET cyclotron.

    Science.gov (United States)

    Ogata, Yoshimune; Ishigure, Nobuhito; Mochizuki, Shingo; Ito, Kengo; Hatano, Kentaro; Abe, Junichiro; Miyahara, Hiroshi; Masumoto, Kazuyoshi; Nakamura, Hajime

    2011-05-01

    The number of positron emission tomography (PET) examinations has greatly increased world-wide. Since positron emission nuclides for the PET examinations have short half-lives, they are mainly produced using on-site cyclotrons. During the production of the nuclides, significant quantities of neutrons are generated from the cyclotrons. Neutrons have potential to activate the materials around the cyclotrons and cause exposure to the staff. To investigate quantities and distribution of the thermal neutrons, thermal neutron fluxes were measured around a PET cyclotron in a laboratory associating with a hospital. The cyclotron accelerates protons up to 18 MeV, and the mean particle current is 20 μA. The neutron fluxes were measured during both 18F production and C production. Gold foils and thermoluminescent dosimeter (TLD) badges were used to measure the neutron fluxes. The neutron fluxes in the target box averaged 9.3 × 10(6) cm(-2) s(-1) and 1.7 × 10(6) cm(-2) s(-1) during 18F and 11C production, respectively. Those in the cyclotron room averaged 4.1 × 10(5) cm(-2) s(-1) and 1.2 × 10(5) cm(-2) s(-1), respectively. Those outside the concrete wall shielding were estimated as being equal to or less than ∼3 cm s, which corresponded to 0.1 μSv h(-1) in effective dose. The neutron fluxes outside the concrete shielding were confirmed to be quite low compared to the legal limit.

  19. Staphylococcus aureus Quorum Regulator SarA Targeted Compound, 2-[(Methylaminomethyl]phenol Inhibits Biofilm and Down-Regulates Virulence Genes

    Directory of Open Access Journals (Sweden)

    P. Balamurugan

    2017-07-01

    Full Text Available Staphylococcus aureus is a widely acknowledged Gram-positive pathogen for forming biofilm and virulence gene expressions by quorum sensing (QS, a cell to cell communication process. The quorum regulator SarA of S. aureus up-regulates the expression of many virulence factors including biofilm formation to mediate pathogenesis and evasion of the host immune system in the late phases of growth. Thus, inhibiting the production or blocking SarA protein might influence the down-regulation of biofilm and virulence factors. In this context, here we have synthesized 2-[(Methylaminomethyl]phenol, which was specifically targeted toward the quorum regulator SarA through in silico approach in our previous study. The molecule has been evaluated in vitro to validate its antibiofilm activity against clinical S. aureus strains. In addition, antivirulence properties of the inhibitor were confirmed with the observation of a significant reduction in the expression of representative virulence genes like fnbA, hla and hld that are governed under S. aureus QS. Interestingly, the SarA targeted inhibitor showed negligible antimicrobial activity and markedly reduced the minimum inhibitory concentration of conventional antibiotics when used in combination making it a more attractive lead for further clinical tests.

  20. Intergovernmental consultation and coordination and emergency response: The relationship between ICCB (Intergovernmental Consultation and Coordination Board) and SARA (Superfund Amendments and Reauthorization Act of 1986) Title III in the US Army's Chemical Stockpile Disposal Program

    Energy Technology Data Exchange (ETDEWEB)

    Feldman, D.L.

    1989-02-01

    The relationship between Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA) and the Intergovernmental Consultation and Coordination Board (ICCB) in the US Army's Chemical Stockpile Disposal Program (CSDP) is examined from four perspectives: (1) the current status and likely future direction of SARA implementation in the eight CSDP continental United States sites; (2) the applicability of SARA to the CSDP; (3) the effect of SARA information management upon the ICCB; and (4) challenges posed by SARA in the areas of public participation and intergovernmental relations which make the interface between emergency planning and intergovernmental relations in the CSDP more complex than originally envisioned in the program's Final Programmatic Environmental Impact Statement. The emergency planning structures developed by SARA have important parallels with the CSDP's ICCB. It is important to maintain a separation between these emergency planning structures and ICCBs, which will handle additional concerns other than emergency planning. While considerable variation exists in patterns of SARA Title III implementation in CSDP states, shared characteristics include: (1) Local Emergency Planning Committees (LEPCs) faced with problems of staffing, resources, and membership attrition; (2) unclear lines of planning authority in some LEPCs; and (3) the legitimization of unconventional participation in emergency planning. 34 refs., 1 tab.

  1. Construct Validity and Reliability of the SARA Gait and Posture Sub-scale in Early Onset Ataxia

    Directory of Open Access Journals (Sweden)

    Tjitske F. Lawerman

    2017-12-01

    Full Text Available Aim: In children, gait and posture assessment provides a crucial marker for the early characterization, surveillance and treatment evaluation of early onset ataxia (EOA. For reliable data entry of studies targeting at gait and posture improvement, uniform quantitative biomarkers are necessary. Until now, the pediatric test construct of gait and posture scores of the Scale for Assessment and Rating of Ataxia sub-scale (SARA is still unclear. In the present study, we aimed to validate the construct validity and reliability of the pediatric (SARAGAIT/POSTURE sub-scale.Methods: We included 28 EOA patients [15.5 (6–34 years; median (range]. For inter-observer reliability, we determined the ICC on EOA SARAGAIT/POSTURE sub-scores by three independent pediatric neurologists. For convergent validity, we associated SARAGAIT/POSTURE sub-scores with: (1 Ataxic gait Severity Measurement by Klockgether (ASMK; dynamic balance, (2 Pediatric Balance Scale (PBS; static balance, (3 Gross Motor Function Classification Scale -extended and revised version (GMFCS-E&R, (4 SARA-kinetic scores (SARAKINETIC; kinetic function of the upper and lower limbs, (5 Archimedes Spiral (AS; kinetic function of the upper limbs, and (6 total SARA scores (SARATOTAL; i.e., summed SARAGAIT/POSTURE, SARAKINETIC, and SARASPEECH sub-scores. For discriminant validity, we investigated whether EOA co-morbidity factors (myopathy and myoclonus could influence SARAGAIT/POSTURE sub-scores.Results: The inter-observer agreement (ICC on EOA SARAGAIT/POSTURE sub-scores was high (0.97. SARAGAIT/POSTURE was strongly correlated with the other ataxia and functional scales [ASMK (rs = -0.819; p < 0.001; PBS (rs = -0.943; p < 0.001; GMFCS-E&R (rs = -0.862; p < 0.001; SARAKINETIC (rs = 0.726; p < 0.001; AS (rs = 0.609; p = 0.002; and SARATOTAL (rs = 0.935; p < 0.001]. Comorbid myopathy influenced SARAGAIT/POSTURE scores by concurrent muscle weakness, whereas comorbid myoclonus predominantly influenced

  2. A new RF system for a rejuvenated Synchro-cyclotron

    CERN Multimedia

    1975-01-01

    The Synchro-cyclotron is shown here shortly after the completion of the improvement programme, which left the steel magnet yoke as almost the only remaining component of the original machine. On the left can be seen the rotary condenser which produces the frequency modulation required for the acceleration (one of a pair available -in this instance ROTCO II). (see photo 7506015)

  3. Study of microwave components for an electron cyclotron resonance ...

    Indian Academy of Sciences (India)

    Keywords. Microwave system; microwave studio software; network analyser; electron cyclotron resonance ion source. ... of ∼13 eV was obtained. This article describes various aspects of the microwave system including design, fabrication, characterization and performance studies of the microwave components.

  4. Development of beam instruments at JAERI cyclotron facility

    Energy Technology Data Exchange (ETDEWEB)

    Okumura, Susumu; Fukuda, Mitsuhiro; Ishibori, Ikuo; Agematsu, Takashi; Yokota, Watalu; Nara, Takayuki; Nakamura, Yoshiteru; Arakawa, Kazuo [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    A beam phase monitor and two kinds of fluence distribution monitors have been developed for measuring characteristics of cyclotron beams. The beam phase monitor provides a beam phase signal for tuning a beam chopping system and a beam phase selection system. A two-dimensional fluence distribution on a large area is measured with fluence distribution monitors. (author)

  5. The electron cyclotron absorption diagnostic at the Rijnhuizen tokamak project

    NARCIS (Netherlands)

    van Gelder, J. F. M.; Miedema, H. S.; Donne, A. J. H.; Oomens, A. A. M.; Schüller, F. C.

    1997-01-01

    A new 20-channel electron cyclotron absorption diagnostic has been developed at the Rijnhuizen tokamak project. It is the first time the electron pressure profile in a tokamak plasma can be measured directly with a time resolution of 1 ms. The diagnostic measures simultaneously the emission and

  6. Electron cyclotron resonance heating in a short cylindrical plasma ...

    Indian Academy of Sciences (India)

    Electron cyclotron resonance (ECR) plasma is produced and studied in a small cylindrical system. Microwave power is delivered by a CW magnetron at 2.45 GHz in TE10 mode and launched radially to have extraordinary (X) wave in plasma. The axial magnetic field required for ECR in the system is such that the first two ...

  7. Unstable Electrostatic Ion Cyclotron Waves Exited by an Ion Beam

    DEFF Research Database (Denmark)

    Michelsen, Poul; Pécseli, Hans; Juul Rasmussen, Jens

    1976-01-01

    Electrostatic ion cyclotron waves were observed in a quiescent cesium plasma into which a low‐energy beam of sodium ions was injected. The instability appeared when the beam velocity was above 12 times the ion thermal velocity. The waves propagated along the magnetic field with a velocity somewhat...

  8. Cyclotron Resonance of Electrons Trapped in a Microwave Cavity

    Science.gov (United States)

    Elmore, W. C.

    1975-01-01

    Describes an experiment in which the free-electron cyclotron resonance of electrons trapped in a microwave cavity by a Penning trap is observed. The experiment constitutes an attractive alternative to one of the Gardner-Purcell variety. (Author/GS)

  9. Ion-Beam-Excited, Electrostatic, Ion Cyclotron Instability

    DEFF Research Database (Denmark)

    Michelsen, Poul; Pécseli, Hans; Juul Rasmussen, Jens

    1977-01-01

    The stability limits of the ion‐beam‐excited, electrostatic, ion cyclotron instability were investigated in a Q‐machine plasma where the electrons could be heated by microwaves. In agreement with theory, the beam energy necessary for excitation decreased with increasing electron temperature....

  10. Ion-Beam-Excited Electrostatic Ion Cyclotron Instability

    DEFF Research Database (Denmark)

    Michelsen, Poul; Pécseli, Hans; Juul Rasmussen, Jens

    1977-01-01

    The stability limits of the ion‐beam‐excited, electrostatic, ion cyclotron instability were investigated in a Q‐machine plasma where the electrons could be heated by microwaves. In agreement with theory, the beam energy necessary for excitation decreased with increasing electron temperature....

  11. Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 35

    Energy Technology Data Exchange (ETDEWEB)

    1986-10-29

    Efforts are reported on the installation and checkout of cyclotron components which had been previously fabricated. Final integration of subsystems and major systems leading to internal beam tests is reported near completion. Progress is reported in relation to control system components, focus and steering magnet design, and rf system testing. (LEW)

  12. Wave propagation through an electron cyclotron resonance layer

    NARCIS (Netherlands)

    Westerhof, E.

    1997-01-01

    The propagation of a wave beam through an electron cyclotron resonance layer is analysed in two-dimensional slab geometry in order to assess the deviation from cold plasma propagation due to resonant, warm plasma changes in wave dispersion. For quasi-perpendicular propagation, N-parallel to x

  13. Radiation safety aspects of the AGOR superconducting cyclotron facility

    NARCIS (Netherlands)

    Beijers, JPM; de Meijer, RJ

    1996-01-01

    This paper describes shielding calculations and skyshine estimates for the new AGOR K=600 superconducting cyclotron facility. Both simple, semi-empirical models and Monte-Carlo simulations were used. The calculations are based on a 200 MeV proton beam incident on a trick aluminum target. Also the

  14. Electron cyclotron resonance breakdown studies in a linear plasma ...

    Indian Academy of Sciences (India)

    Abstract. Electron cyclotron resonance (ECR) plasma breakdown is studied in a small linear cylindrical system with four different gases – hydrogen, helium, argon and nitrogen. Microwave power in the experimental system is delivered by a magnetron at 2.45 ± 0.02. GHz in TE10 mode and launched radially to have ...

  15. A micropulse monitor for control of cyclotron beams

    Science.gov (United States)

    Lind, D. A.; Peterson, R. J.; Da Silva, A. G.; Auler, L. T.; de Barros, S.

    1990-07-01

    A system using wall current monitors to observe the time structure of the individual beam current pulses of the Cyclotron Corp. CV28 cyclotron installed at the Instituto de Engenharia Nuclear of CNEN in Rio de Janeiro is described. The monitors are designed to give a faithful representation of the actual beam pulse, so the effects on the longitudinal phase space could be seen as the cyclotron parameters were changed. Beam pulses of width in the range of 1 to 4 ns and with a charge of 7 × 10-16 C or greater can be observed. With two units in the line transit times permit beam energy determination as well as charge distribution. For timing purposes a unit placed in front of a target is used to generate a start signal for time-of-flight measurements, and to monitor the effects of all parameters of the cyclotron tune. By measuring flight times in the beamlines of this machine, the energy for 28 MeV protons can be determined to about 50 keV and for the other available particles to about 30 keV.

  16. Study of microwave components for an electron cyclotron resonance ...

    Indian Academy of Sciences (India)

    rious aspects of the microwave system including design, fabrication, characterization and performance studies of the microwave components. Keywords. Microwave system; microwave studio software; network analyser; electron cyclotron resonance ion source. 1. Introduction. Microwave systems at 2.45 GHz have been ...

  17. The development of technology for the improvement of cyclotron performance

    Energy Technology Data Exchange (ETDEWEB)

    Chai, Jong Seo; Kim, Y. S.; Ha, J. H.; Lee, M. Y.; Lee, H. S

    1999-05-01

    We show the first-order beam optics theory which is a simplified theory that can be used to carry out the initial design of a cyclotron. Based on this, a computer program has been developed to determine main cyclotron parameters such as number of magnet sectors, sector angle, hill and valley fields, and overall size of the cyclotron etc. We then show the result of two-dimensional magnetic field calculation using POISSON program. By using this program, one can determine magnet yoke geometry and the average magnetic fields etc. Finally, the three-dimensional computer program OPERA-3D had been invoked to determine magnet pole tips (i.e. sector). Validity of the design can be seen by investigating magnetic fields, radial and vertical focusing frequencies as a function of the beam energy. In this report, we show the results of cyclotron magnet design. And we designed 72 MHz RF system and ion source system. We tested RF resonance each coupling methods. We show the result of RF design and prototype operation. Our developed ion source is PIG type. We described our design methods and implementation. We report the result of getting negative hydrogen ion.

  18. Second-harmonic ion cyclotron resonance heating scenarios of ...

    Indian Academy of Sciences (India)

    ... Refresher Courses · Symposia · Live Streaming. Home; Journals; Pramana – Journal of Physics; Volume 85; Issue 4. Second-harmonic ion cyclotron resonance heating scenarios of Aditya tokamak plasma. Asim Kumar Chattopadhyay S V Kulkarni R Srinivasan Aditya Team. Volume 85 Issue 4 October 2015 pp 713-721 ...

  19. Nuclear physics with superconducting cyclotron at Kolkata: Scopes ...

    Indian Academy of Sciences (India)

    At the same time, the nuclear physics programme and related experimental facility development activities are taking shape. A general review of the nuclear physics research opportunities with the superconducting cyclotron and the present status of the development of different detector arrays and other experimental facilities ...

  20. Unstable plasma characteristics in mirror field electron cyclotron ...

    Indian Academy of Sciences (India)

    Electron cyclotron plasma reactor are prone to instabilities in specific input power [3–7] region (150–450 watts). In this region power absorption by gas molecules in the cavity is very poor and enhanced input power gets reflected substantially without increasing ion density. There are abrupt changes in plasma characteristics ...

  1. Application of compact electron cyclotron resonance ion source

    NARCIS (Netherlands)

    Muramatsu, M.; Kitagawa, A.; Iwata, Y.; Ogawa, H.; Hojo, S.; Kubo, T.; Kato, Y.; Biri, S.; Fekete, E.; Yoshida, Y.; Drentje, A. G.

    The compact electron cyclotron resonance (ECR) ion source with a permanent magnet configuration (Kei2 source) has been developed at National Institute of Radiological Sciences for a new carbon therapy facility. The Kei2 source was designed for production of C(4+) ions; its performance such as beam

  2. Memoria de la guerra civil española. Entre el sol y la tormenta de Sara Berenguer

    Directory of Open Access Journals (Sweden)

    Helena López

    2013-07-01

    Full Text Available En este artículo pretendo analizar dos cuestiones en relación con las memorias de guerra de la militante anarquista Sara Berenguer. En primer lugar, quiero atender a las estrategias discursivas (clase, género, sexualidad de construcción de la subjetividad en este texto. Además, me interesa indagar cómo estos discursos se interseccionan con la posición espacio-temporal (tiempo de la memoria y tiempo-espacio del exilio del sujeto autobiográfico. Mi objetivo principal es proponer una problematización de los conceptos de “memoria colectiva” y de “experiencia femenina” y reivindicar, por lo tanto, la relevancia tanto teórica como política de análisis críticos basados en narrativas personales.

  3. Cyclotron Phase-Coherent Ion Spatial Dispersion in a Non-Quadratic Trapping Potential is Responsible for FT-ICR MS at the Cyclotron Frequency

    Science.gov (United States)

    Nagornov, Konstantin O.; Kozhinov, Anton N.; Tsybin, Yury O.

    2017-11-01

    Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS) at the cyclotron frequency instead of the reduced cyclotron frequency has been experimentally demonstrated using narrow aperture detection electrode (NADEL) ICR cells. Here, based on the results of SIMION simulations, we provide the initial mechanistic insights into the cyclotron frequency regime generation in FT-ICR MS. The reason for cyclotron frequency regime is found to be a new type of a collective motion of ions with a certain dispersion in the initial characteristics, such as pre-excitation ion velocities, in a highly non-quadratic trapping potential as realized in NADEL ICR cells. During ion detection, ions of the same m/z move in phase for cyclotron ion motion but out of phase for magnetron (drift) ion motion destroying signals at the fundamental and high order harmonics that comprise reduced cyclotron frequency components. After an initial magnetron motion period, ion clouds distribute into a novel type of structures - ion slabs, elliptical cylinders, or star-like structures. These structures rotate at the Larmor (half-cyclotron) frequency on a plane orthogonal to the magnetic field, inducing signals at the true cyclotron frequency on each of the narrow aperture detection electrodes. To eliminate the reduced cyclotron frequency peak upon dipolar ion detection, a number of slabs or elliptical cylinders organizing a star-like configuration are formed. In a NADEL ICR cell with quadrupolar ion detection, a single slab or an elliptical cylinder is sufficient to minimize the intensity of the reduced cyclotron frequency components, particularly the second harmonic. [Figure not available: see fulltext.

  4. sarA negatively regulates Staphylococcus epidermidis biofilm formation by modulating expression of 1 MDa extracellular matrix binding protein and autolysis‐dependent release of eDNA

    National Research Council Canada - National Science Library

    Christner, Martin; Heinze, Constanze; Busch, Michael; Franke, Gefion; Hentschke, Moritz; Bayard Dühring, Sara; Büttner, Henning; Kotasinska, Marta; Wischnewski, Victoria; Kroll, Gesche; Buck, Friedrich; Molin, Soeren; Otto, Michael; Rohde, Holger

    2012-01-01

    ... . Transposon mutagenesis of clinical significant but biofilm‐negative S . epidermidis 1585 was used to isolate a biofilm positive mutant carrying a Tn 917 insertion in sarA , chief regulator of staphylococcal virulence...

  5. Summary of EC-17: the 17th Joint Workshop on Electron Cyclotron Emission and Electron Cyclotron Resonance Heating (Deurne, The Netherlands, 7-10 May 2012)

    NARCIS (Netherlands)

    Westerhof, E.; Austin, M. E.; Kubo, S.; Lin-Liu, Y. R.; Plaum, B.

    2013-01-01

    An overview is given of the papers presented at the 17th Joint Workshop on Electron Cyclotron Emission (ECE) and Electron Cyclotron Resonance Heating (ECRH). The meeting covered all aspects of the research field ranging from theory to enabling technologies. From the workshop, advanced control by

  6. Feminism and Faith: Exploring Christian Spaces in the Writing of Sara Maitland and Michèle Roberts

    Directory of Open Access Journals (Sweden)

    Arina LUNGU-CIRSTEA

    2011-03-01

    Full Text Available En 1983, les féministes britanniques Sara Maitland et Jo Garcia ont publié Walking on the Water (London : Virago, une collection d’essais, de récits, de poèmes et de photos produits par des femmes sur le thème de la spiritualité. Les contributrices ont été en particulier invitées à explorer la relation entre leur identité féministe et leurs croyances religieuses. Le ton de ces contributions varie fortement, allant de l’envie passionnée de concilier les objectifs du féminisme avec le christianisme à un rejet total de l’Eglise comme institution patriarcale suprême. Cet article met en dialogue des récits diamétralement opposés du rapport entre christianisme et féminisme en s’intéressante plus particulièrement à deux des contributrices, Sara Maitland (1950 - et Michèle Roberts (1949 - . Ces deux écrivaines, qui se sont activement impliquées dans les mouvements féministes des années 1970, ont toutes deux lutté pour se réconcilier avec leur héritage chrétien. Néanmoins, alors que Maitland tente essentiellement de revisiter le christianisme en y incorporant les points essentiels d’une idéologie féministe, Roberts sent le besoin impérieux de se défaire de son identité religieuse afin de devenir indépendante ; en effet, dans son autobiographie Paper Houses (2007 elle décrit son éducation catholique comme “autoritaire et misogyne” (16. Cet article explore les façons dont l’identité spirituelle se construit dans le jeu complexe des interactions entre féminisme et foi. Il se propose, dans une perspective comparatiste, d’analyser d’une part le recueil de nouvelles de Sara Maitland intitulé A Book of Spells, et d’autre part, le roman acclamé de Michèle Roberts, Daughters of the House. Dans ces écrits, Maitland et Roberts ont un objectif commun qui est de renégocier la place des femmes dans l’histoire chrétienne dont elles reconnaissent – il est vrai à partir de perspectives diff

  7. Electron cyclotron emission imaging diagnostic system for Rijnhuizen Tokamak Project

    Energy Technology Data Exchange (ETDEWEB)

    Deng, B.H.; Hsia, R.P.; Domier, C.W.; Burns, S.R.; Hillyer, T.R.; Luhmann, N.C. Jr. [University of California at Davis, 228 Walker Hall, Davis, California 95616 (United States); Oyevaar, T.; Donne, A.J. [FOM-Inst. voor Plasmafysica Rijnhuizen, Association Euratom-FOM (International organizations without location); RTP team

    1999-01-01

    A 16-channel electron cyclotron emission (ECE) imaging diagnostic system has been developed and installed on the Rijnhuizen Tokamak Project for measuring plasma electron cyclotron emission with a temporal resolution of 2 {mu}s. The high spatial resolution of the system is achieved by utilizing a low cost linear mixer/receiver array. Unlike conventional ECE diagnostics, the sample volumes of the ECE imaging system are aligned vertically, and can be shifted across the plasma cross-section by varying the local oscillator frequency, making possible 2D measurements of electron temperature profiles and fluctuations. The poloidal/radial wavenumber spectra and correlation lengths of T{sub e} fluctuations in the plasma core can also be obtained by properly positioning the focal plane of the imaging system. Due to these unique features, ECE imaging is an ideal tool for plasma transport study. Technical details of the system are described, together with preliminary experimental results. {copyright} {ital 1999 American Institute of Physics.}

  8. Studies of radioisotope production with an AVF cyclotron in TIARA

    Energy Technology Data Exchange (ETDEWEB)

    Sekine, Toshiaki [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1997-03-01

    The production of radioisotopes to be used mainly for nuclear medicine and biology is studied with an AVF cyclotron in TIARA. A production method of no-carrier-added {sup 186}Re with the {sup 186}W(p,n){sup 186}Re reaction has been developed; this product may be used as a therapeutic agent in radioimmunotherapy due to the adequate nuclear and chemical properties. For the study of the function of plants using a positron-emitter two-dimensional imaging system, a simple method of producing the positron emitter {sup 18}F in water was developed by taking advantage of a highly-energetic {alpha} beam from the AVF cyclotron. (author)

  9. Target development for diversified irradiations at a medical cyclotron.

    Science.gov (United States)

    Spellerberg, S; Scholten, B; Spahn, I; Bolten, W; Holzgreve, M; Coenen, H H; Qaim, S M

    2015-10-01

    The irradiation facility at an old medical cyclotron (Ep=17 MeV; Ed=10 MeV) was upgraded by extending the beam line and incorporation of solid state targetry. Tests performed to check the quality of the available beam are outlined. Results on nuclear data measurements and improvement of radiochemical separations are described. Using solid targets, with the proton beam falling at a slanting angle of 20°, a few radionuclides, e.g. (75)Se, (120)I, (124)I, etc. were produced with medium currents (up to 20 µA) in no-carrier-added form in quantities sufficient for local use. The extended irradiation facility has considerably enhanced the utility of the medical cyclotron. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Neutron spectra due (13)N production in a PET cyclotron.

    Science.gov (United States)

    Benavente, J A; Vega-Carrillo, H R; Lacerda, M A S; Fonseca, T C F; Faria, F P; da Silva, T A

    2015-05-01

    Monte Carlo and experimental methods have been used to characterize the neutron radiation field around PET (Positron Emission Tomography) cyclotrons. In this work, the Monte Carlo code MCNPX was used to estimate the neutron spectra, the neutron fluence rates and the ambient dose equivalent (H*(10)) in seven locations around a PET cyclotron during (13)N production. In order to validate these calculations, H*(10) was measured in three sites and were compared with the calculated doses. All the spectra have two peaks, one above 0.1MeV due to the evaporation neutrons and another in the thermal region due to the room-return effects. Despite the relatively large difference between the measured and calculated H*(10) for one point, the agreement was considered good, compared with that obtained for (18)F production in a previous work. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Physics of electron cyclotron current drive on DIII-D

    CERN Document Server

    Petty, C C; Harvey, R W; Kinsey, J E; Lao, L L; Lohr, J; Luce, T C; Makowski, M A; Prater, R

    2002-01-01

    OAK A271 PHYSICS OF ELECTRON CYCLOTRON CURRENT DRIVE ON DIII-D. Recent experiments on the DIII-D tokamak have focused on determining the effect of trapped particles on the electron cyclotron current drive (ECCD) efficiency. The measured ECCD efficiency increases as the deposition location is moved towards the inboard midplane or towards smaller minor radius for both co and counter injection. The measured ECCD efficiency also increases with increasing electron density and/or temperature. The experimental ECCD is compared to both the linear theory (Toray-GA) as well as a quasilinear Fokker-Planck model (CQL3D). The experimental ECCD is found to be in better agreement with the more complete Fokker-Planck calculation, especially for cases of high rf power density and/or loop voltage. The narrow width of the measured ECCD profile is consistent with only low levels of radial transport for the current carrying electrons.

  12. Ernest Orlando Lawrence (1901-1958), Cyclotron and Medicine

    Energy Technology Data Exchange (ETDEWEB)

    Chu, William T.

    2005-09-01

    On August 8, 2001, Lawrence Berkeley National Laboratory celebrated the centennial of the birth of its founder (and namesake), Ernest Orlando Lawrence. For the occasion, many speeches were given and old speeches were remembered. We recall the words of the late Luis Alvarez, a Nobel Laureate and one of the Lawrence's closest colleagues: ''Lawrence will always be remembered as the inventor of the cyclotron, but more importantly, he should be remembered as the inventor of the modern way of doing science''. J. L. Heilbron and R. W. Seidel, in the introduction of their book, ''Lawrence and His Laboratory'' stated, ''The motives and mechanisms that shaped the growth of the Laboratory helped to force deep changes in the scientific estate and in the wider society. In the entrepreneurship of its founder, Ernest Orlando Lawrence, these motives, mechanisms, and changes came together in a tight focus. He mobilized great and small philanthropists, state and local governments, corporations, and plutocrats, volunteers and virtuosos. The work they supported, from astrophysics and atomic bombs, from radiochemistry to nuclear medicine, shaped the way we observe, control, and manipulate our environment.'' Indeed, all over the civilized world, the ways we do science changed forever after Lawrence built his famed Radiation Laboratory. In this editorial, we epitomize his legacy of changing the way we do medicine, thereby affecting the health and well being of all humanity. This year marks the 75th anniversary of the invention of the cyclotron by Ernest Orlando Lawrence at the University of California at Berkeley. Lawrence conceived the idea of the cyclotron early in 1929 after reading an article by Rolf Wideroe on high-energy accelerators. In the spring of 1930 one of his students, Nels Edlefsen, constructed two crude models of a cyclotron. Later in the fall of the same year, another student, M. Stanley Livingston

  13. Converting an AEG Cyclotron to H- Acceleration and Extraction

    Science.gov (United States)

    Ramsey, Fred; Carroll, Lewis; Rathmann, Tom; Huenges, Ernst; Bechtold, Matthias Mentler Volker

    2009-03-01

    Clinical Trials are under way to evaluate agents labeled with the nuclide 225Ac and its decay product 213Bi, in targeted alpha-immuno-therapy [1]. 225Ac can be produced on a medium-energy cyclotron via the nuclear reaction 226Ra(p,n)225Ac. To demonstrate proof-of-principle, a vintage AEG cyclotron, Model E33 [2], with an internal target, had been employed in a pilot production program at the Technical University of Munich (TUM). To enhance production capability and further support the clinical studies, the TUM facility has recently been refurbished and upgraded, adding a new external beam-line, automated target irradiation and transport systems, new laboratories, hot cells, etc. [3]. An improved high-power rotating target has been built and installed [4]. The AEG cyclotron itself has also been modified and upgraded to accelerate and extract H- ions. We have designed, built, and tested a new axial Penning-type ion source which is optimized for the production of H- ions. The ion source has continued to evolve through experiment and experience. Steady improvements in materials and mechanics have led to enhanced source stability, life-time, and H- production. We have also designed and built a precision H- charge-exchange beam-extraction system which is equipped with a vacuum lock. To fit within the tight mechanical constraint imposed by the narrow magnet gap, the system incorporates a novel chain-drive foil holder and foil-changer mechanism. The reconfigured cyclotron system has now been in operation for more than 1 year. Three long-duration target irradiations have been conducted. The most recent bombardment ran 160 continuous hours at a beam on target of ˜80 microamperes for a total yield of ˜70 milli-curies of 225Ac.

  14. Shielding simulation of the CDTN cyclotron bunker using MCNP

    Energy Technology Data Exchange (ETDEWEB)

    Dalle, Hugo M.; Campolina, Daniel de A.M., E-mail: dallehm@cdtn.b, E-mail: campolina@cdtn.b [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Div. de Reatores e Radiacoes

    2011-07-01

    The Nuclear Technology Development Centre (CDTN/CNEN) has contracted services from General Electric in order to install a cyclotron for radioisotopes production and PET radiopharmaceutical synthesis. The Monte Carlo code MCNP5 was used to determine the TVL (tenth value layer) of the concrete and verify shielding calculations performed by GE. The simulations results show values of equivalent dose rates in agreement with those calculated using the methodology adopted by GE, the NCRP-144 and the NCRP-51. (author)

  15. Cyclotron Auto-Resonance Accelerator for environmental applications

    Science.gov (United States)

    Jiang, Yong; Shchelkunov, Sergey V.; Hirshfield, Jay L.

    2017-03-01

    A MW-level CW electron beam source for environmental remediation based on extensions of the scientifically-proven Cyclotron Auto-Resonance Accelerator, dubbed CARA, is described here. CARA is distinguished by its exceptionally high RF-to-beam efficiency, by its production of a self-scanning beam, and by its proportionately lower specific power loading on a beam output window. Its environmental applications include sterilization, flue gas and waste water treatment.

  16. Electron Cyclotron Waves Polarization in the TJII Stellarator

    Energy Technology Data Exchange (ETDEWEB)

    Cappa, A.; Martinez-Fernandez, J.; Wagner, D.

    2013-05-01

    This report describes the theoretical calculations related with the electron cyclotron (EC) waves polarization control in the TJII stellarator. Two main aspects will be distinguished: the determination of the vacuum polarization that the wave must exhibit if a given propagation mode in a cold plasma is desired and the calculation of the behavior of the grooved polarizers and other transmission systems used to launch the vacuum wave with the required polarization. (Author) 13 refs.

  17. Ion–Cyclotron Resonance Frequency Interval Dependence on the O ...

    Indian Academy of Sciences (India)

    The frequency intervals in which O VI ions get in resonance with ion–cyclotron waves are calculated using the kinetic model, for the latest six values found in literature on O VI ion number densities in the 1.5–3 region of the NPCH. It is found that the common resonance interval is 1.5 kHz to 3 kHz. The -variations of wave ...

  18. Beaudrie, Sara, Ducar, Cynthia, & Potowski, Kim (2014. Heritage language teaching: Research and practice. New York State, New York: McGraw Hill.

    Directory of Open Access Journals (Sweden)

    Florencia Henshaw

    2015-12-01

    Full Text Available This review introduces readers to Heritage language teaching: Research and practice, by Sara Beaudrie, Cynthia Ducar, and Kim Potowski, which is part of the “Directions in Second Language Learning” series. This handbook offers a comprehensive overview of key concepts, research findings, and pedagogical strategies to better meet the needs of heritage learners, and it underscores the importance of sociolinguistic issues and phenomena in heritage language instruction.

  19. Beaudrie, Sara, Ducar, Cynthia, & Potowski, Kim (2014). Heritage language teaching: Research and practice. New York State, New York: McGraw Hill.

    OpenAIRE

    Florencia Henshaw

    2015-01-01

    This review introduces readers to Heritage language teaching: Research and practice, by Sara Beaudrie, Cynthia Ducar, and Kim Potowski, which is part of the “Directions in Second Language Learning” series. This handbook offers a comprehensive overview of key concepts, research findings, and pedagogical strategies to better meet the needs of heritage learners, and it underscores the importance of sociolinguistic issues and phenomena in heritage language instruction.

  20. Modern compact accelerators of cyclotron type for medical applications

    Science.gov (United States)

    Smirnov, V.; Vorozhtsov, S.

    2016-09-01

    Ion beam therapy and hadron therapy are types of external beam radiotherapy. Recently, the vast majority of patients have been treated with protons and carbon ions. Typically, the types of accelerators used for therapy were cyclotrons and synchrocyclotrons. It is intuitively clear that a compact facility fits best to a hospital environment intended for particle therapy and medical diagnostics. Another criterion for selection of accelerators to be mentioned in this article is application of superconducting technology to the magnetic system design of the facility. Compact isochronous cyclotrons, which accelerate protons in the energy range 9-30 MeV, have been widely used for production of radionuclides. Energy of 230 MeV has become canonical for all proton therapy accelerators. Similar application of a carbon beam requires ion energy of 430 MeV/u. Due to application of superconducting coils the magnetic field in these machines can reach 4-5 T and even 9 T in some cases. Medical cyclotrons with an ironless or nearly ironless magnetic system that have a number of advantages over the classical accelerators are in the development stage. In this work an attempt is made to describe some conceptual and technical features of modern accelerators under consideration. The emphasis is placed on the magnetic and acceleration systems along with the beam extraction unit, which are very important from the point of view of the facility compactness and compliance with the strict medical requirements.

  1. Quench analysis of a novel compact superconducting cyclotron

    Science.gov (United States)

    Ghosh, Sundeep; Dutta Gupta, Anjan; Kanti Dey, Malay; Pal, Gautam

    2017-02-01

    Design and analysis of a compact superconducting cyclotron dedicated for medical applications in the fields of nuclear medicine and therapy is presently being pursued in our organization. The novelty of this cyclotron lies in the fact that it does not consist of any iron-pole. The cyclotron magnet will be made of a set of NbTi coils comprising of solenoid and sector coils which are housed in two halves on either sides of the median plane. The average magnetic field is 1.74 T and the maximum extraction energy is 25 MeV, which is sufficient for production of 99mTc from Mo. In this paper, quench analyses of the coils have been discussed in details considering adiabatic condition. The entire cryostat magnet along with coils, formers and support links were modelled for the quench simulation. Self and mutual inductances of all the coils were obtained from a separate magnetic analysis and used in the simulation. Parametric analyses were carried out with different quench initiation energy at various critical locations on the coil surface. The corresponding quench behaviour, i.e. maximum temperature rise, maximum voltage and current decay in each of the coils have been studied.

  2. A Suzaku View of Cyclotron Line Sources and Candidates

    Science.gov (United States)

    Pottschmidt, K.; Suchy, S.; Rivers, E.; Rothschild, R. E.; Marcu, D. M.; Barragan, L.; Kuehnel, M.; Fuerst, F.; Schwarm, F.; Kreykenbohm, I.; hide

    2012-01-01

    Seventeen accreting neutron star pulsars, mostly high mass X-ray binaries with half of them Be-type transients, are known to exhibit Cyclotron Resonance Scattering Features (CRSFs) in their X-ray spectra, with characteristic line energies from 10 to 60 keY. To date about two thirds of them, plus a few similar systems without known CRSFs, have been observed with Suzaku. We present an overview of results from these observations, including the discovery of a CRSF in the transient IA1118-61 and pulse phase resolved spectroscopy of OX 301-2. These observations allow for the determination of cyclotron line parameters to an unprecedented degree of accuracy within a moderate amount of observing time. This is important since these parameters vary - e.g., with orbital phase, pulse phase, or luminosity - depending on the geometry of the magnetic field of the pulsar and the properties of the accretion column at the magnetic poles. We briefly introduce a spectral model for CRSFs that is currently being developed and that for the first time is based on these physical properties. In addition to cyclotron line measurements, selected highlights from the Suzaku analyses include dip and flare studies, e.g., of 4U 1907+09 and Vela X-I, which show clumpy wind effects (like partial absorption and/or a decrease in the mass accretion rate supplied by the wind) and may also display magnetospheric gating effects.

  3. Emittance Measurement for Beamline Extension at the PET Cyclotron

    Directory of Open Access Journals (Sweden)

    Sae-Hoon Park

    2016-01-01

    Full Text Available Particle-induced X-ray emission is used for determining the elemental composition of materials. This method uses low-energy protons (of several MeV, which can be obtained from high-energy (of tens MeV accelerators. Instead of manufacturing an accelerator for generating the MeV protons, the use of a PET cyclotron has been suggested for designing the beamline for multipurpose applications, especially for the PIXE experiment, which has a dedicated high-energy (of tens MeV accelerator. The beam properties of the cyclotron were determined at this experimental facility by using an external beamline before transferring the ion beam to the experimental chamber. We measured the beam profile and calculated the emittance using the pepper-pot method. The beam profile was measured as the beam current using a wire scanner, and the emittance was measured as the beam distribution at the beam dump using a radiochromic film. We analyzed the measurement results and are planning to use the results obtained in the simulations of external beamline and aligned beamline components. We will consider energy degradation after computing the beamline simulation. The experimental study focused on measuring the emittance from the cyclotron, and the results of this study are presented in this paper.

  4. The cyclotron laboratory and the RFQ accelerator in Bern

    Science.gov (United States)

    Braccini, S.; Ereditato, A.; Kreslo, I.; Nirkko, M.; Scampoli, P.; von Bremen, K.; Weber, M.

    2013-07-01

    Two proton accelerators have been recently put in operation in Bern: an 18 MeV cyclotron and a 2 MeV RFQ linac. The commercial IBA 18/18 cyclotron, equipped with a specifically conceived 6 m long external beam line ending in a separate bunker, will provide beams for routine 18-F and other PET radioisotope production as well as for novel detector, radiation biophysics, radioprotection, radiochemistry and radiopharmacy developments. The accelerator is embedded into a complex building hosting two physics laboratories and four Good Manufacturing Practice (GMP) laboratories. This project is the result of a successful collaboration between the Inselspital, the University of Bern and private investors, aiming at the constitution of a combined medical and research centre able to provide the most cutting-edge technologies in medical imaging and cancer radiation therapy. The cyclotron is complemented by the RFQ with the primary goals of elemental analysis via Particle Induced Gamma Emission (PIGE), and the detection of potentially dangerous materials with high nitrogen content using the Gamma-Resonant Nuclear Absorption (GRNA) technique. In this context, beam instrumentation devices have been developed, in particular an innovative beam profile monitor based on doped silica fibres and a setup for emittance measurements using the pepper-pot technique. On this basis, the establishment of a proton therapy centre on the campus of the Inselspital is in the phase of advanced study.

  5. The cyclotron laboratory and the RFQ accelerator in Bern

    Energy Technology Data Exchange (ETDEWEB)

    Braccini, S.; Ereditato, A.; Kreslo, I.; Nirkko, M.; Weber, M. [Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern (Switzerland); Scampoli, P. [Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics (LHEP), University of Bern, Sidlerstrasse 5, CH-3012 Bern, Switzerland and Department of Physical Sciences, University Federico II, Via Cintia, I-60126 Napoli (Italy); Bremen, K. von [SWAN Isotopen AG, Inselspital, CH-3010 Bern (Switzerland)

    2013-07-18

    Two proton accelerators have been recently put in operation in Bern: an 18 MeV cyclotron and a 2 MeV RFQ linac. The commercial IBA 18/18 cyclotron, equipped with a specifically conceived 6 m long external beam line ending in a separate bunker, will provide beams for routine 18-F and other PET radioisotope production as well as for novel detector, radiation biophysics, radioprotection, radiochemistry and radiopharmacy developments. The accelerator is embedded into a complex building hosting two physics laboratories and four Good Manufacturing Practice (GMP) laboratories. This project is the result of a successful collaboration between the Inselspital, the University of Bern and private investors, aiming at the constitution of a combined medical and research centre able to provide the most cutting-edge technologies in medical imaging and cancer radiation therapy. The cyclotron is complemented by the RFQ with the primary goals of elemental analysis via Particle Induced Gamma Emission (PIGE), and the detection of potentially dangerous materials with high nitrogen content using the Gamma-Resonant Nuclear Absorption (GRNA) technique. In this context, beam instrumentation devices have been developed, in particular an innovative beam profile monitor based on doped silica fibres and a setup for emittance measurements using the pepper-pot technique. On this basis, the establishment of a proton therapy centre on the campus of the Inselspital is in the phase of advanced study.

  6. PRODUCTION OF 11 C-METHIONINE BY CYCLOTRON AVF JAERI

    Directory of Open Access Journals (Sweden)

    Sri Hastini

    2010-06-01

    Full Text Available At the Takasaki-site of JAERI, an AVF cyclotron has been constructed for advanced radiation technology research. The cyclotron produces extracted beams particularly light and heavy ions of proton as well as deutron. Target chamber is available for production of 11CO2 a positron emitter radioisotope, by bombardment of proton from nitrogen gas as a target, by 14 N (p,a 11C reaction. The use of incident energy on target was estimated to be 11 MeV for primary proton energy of 20 MeV and the beam current was 0,1 m A and the irradiation time was 10 minutes for production of 11CO2 and the yield was about 30 MBq (EOBand for irradiation time 15 minutes and the beam current was 1 mA for production of 11C-Methionine, the yield was about 70 MBq (EOB. Remotely operated automatic and semiautomatic processing systems are used for the production of the 11 C-Methionine agent and the radiochemical purity of the product obtained was determined by High Performance Liquid Chromatography (HPLC with cation exchange column was LC 10 AD MERCK LICHROSPHER 100 RP-18 and the mobile phase was 10 mM ammonium phormmate, the mean of retention time was 1,815 minutes and the radiochemical purity to be more than 90 %. The product was used for plant studies and visualized by PETIS (Positron Emission Tracer Imaging System   Keywords: cyclotron, Positron emitter, 11C-Methionine.

  7. EURAC: A liquid target neutron spallation source using cyclotron technology

    Science.gov (United States)

    Perlado, J. M.; Mínguez, E.; Sanz, J.; Piera, M.

    1995-09-01

    Euratom/JRC Ispra led some years ago the design of an accelerator based neutron spallation source EURAC, with special emphasis as a fusion material testing device. DENIM was involved in the development of the last version of this source. EURAC proposes to use a beam of 600 MeV or 1.5 GeV protons, produced by an effective and low cost ring cyclotron with a current of 6 mA impinging in a liquid lead, or lead-bismuth, target. It will use an advanced cyclotron technology which can be implemented in the next future, in the line of the actual technology of the upgraded SIN-type cyclotron. The adjacent rows to the target correspond to the lead, or Li17Pb83, cooled channels where the samples will be located. The available volumes there were shown enough for material testing purposes. Here, proposal of using those experimental areas to introduce small masses of radioactive wastes for testing of transmutation in spallation source is made. In addition, extrapolation of present conceptual design to make available larger volumes under flexible conditions seems to be possible. Neutrons leaking from the test zone drive a subcritical booster (hidrogen moderator in the center.

  8. Coordinated Micro-Variability CIRCE Polarimetry and SARA JKT Multi-Frequency Photometry Observations of the Blazar S5 0716+71

    Directory of Open Access Journals (Sweden)

    James R. Webb

    2017-11-01

    Full Text Available A critical observation for testing the KRM jet model, in development at FIU, is to observe high time resolution, high accuracy photometry and polarimetry over a wide range of frequencies in the optically thin portion of the synchrotron spectrum. The detection of micro-variability during these observations would be ideal so the background and flaring components could be separated. Target of opportunity H-band photometry and polarimetry observations on the Gran Telescopio Canarias (GTC 10.4-m with the Canarias InfraRed Camera Experiment (CIRCE instrument were made in conjunction with the Southeastern Association for Research in Astronomy (SARA JKT observing in the optical VRI bands in order to test the model. Here we present simultaneous micro-variability observations of Blazar S5 0716+71 made on 14 April 2017, with the CIRCE instrument on the GTC 10.4-m telescope and optical observations made with the 1.0-m SARA JKT in La Palma. The CIRCE observations consisted of high time resolution polarimetric observations in the H band over a period of 2.4 h on source, measuring both the H-band flux and the polarization degree and angle. Simultaneous observations with the SARA JKT 1.0-m yielded VRI light curves with about three minute time resolution over ∼4 h. 0716+71 showed only small amounts of variability during the observation. We present here the resulting data and a comparison to previous observations.

  9. Status of a compact electron cyclotron resonance ion source for National Institute of Radiological Sciences-930 cyclotron.

    Science.gov (United States)

    Hojo, S; Katagiri, K; Nakao, M; Sugiura, A; Muramatsu, M; Noda, A; Okada, T; Takahashi, Y; Komiyama, A; Honma, T; Noda, K

    2014-02-01

    The Kei-source is a compact electron cyclotron resonance ion source using only permanent magnets and a frequency of 10 GHz. It was developed at the National Institute of Radiological Sciences (NIRS) for producing C(4+) ions oriented for high-energy carbon therapy. It has also been used as an ion source for the NIRS-930 cyclotron. Its microwave band region for the traveling-wave-tube amplifier and maximum output power are 8-10 GHz and 350 W, respectively. Since 2006, it has provided various ion beams such as proton, deuteron, carbon, oxygen, and neon with sufficient intensity (200 μA for proton and deuteron, 50 μA for C(4+), for example) and good stability for radioisotope production, tests of radiation damage, and basic research experiments. Its horizontal and vertical emittances were measured using a screen monitor and waist-scan. The present paper reports the current status of the Kei-source.

  10. Status of a compact electron cyclotron resonance ion source for National Institute of Radiological Sciences-930 cyclotron

    Science.gov (United States)

    Hojo, S.; Katagiri, K.; Nakao, M.; Sugiura, A.; Muramatsu, M.; Noda, A.; Okada, T.; Takahashi, Y.; Komiyama, A.; Honma, T.; Noda, K.

    2014-02-01

    The Kei-source is a compact electron cyclotron resonance ion source using only permanent magnets and a frequency of 10 GHz. It was developed at the National Institute of Radiological Sciences (NIRS) for producing C4+ ions oriented for high-energy carbon therapy. It has also been used as an ion source for the NIRS-930 cyclotron. Its microwave band region for the traveling-wave-tube amplifier and maximum output power are 8-10 GHz and 350 W, respectively. Since 2006, it has provided various ion beams such as proton, deuteron, carbon, oxygen, and neon with sufficient intensity (200 μA for proton and deuteron, 50 μA for C4+, for example) and good stability for radioisotope production, tests of radiation damage, and basic research experiments. Its horizontal and vertical emittances were measured using a screen monitor and waist-scan. The present paper reports the current status of the Kei-source.

  11. Static harmonization of dynamically harmonized Fourier transform ion cyclotron resonance cell.

    Science.gov (United States)

    Zhdanova, Ekaterina; Kostyukevich, Yury; Nikolaev, Eugene

    2017-08-01

    Static harmonization in the Fourier transform ion cyclotron resonance cell improves the resolving power of the cell and prevents dephasing of the ion cloud in the case of any trajectory of the charged particle, not necessarily axisymmetric cyclotron (as opposed to dynamic harmonization). We reveal that the Fourier transform ion cyclotron resonance cell with dynamic harmonization (paracell) is proved to be statically harmonized. The volume of the statically harmonized potential distribution increases with an increase in the number of trap segments.

  12. Magnetic Cyclotron Waves near the Proton Cyclotron Frequency in the Solar Wind: Wind and ACE Observations in 2005

    Science.gov (United States)

    Broiles, T. W.; Jian, L.; Stevens, M. L.; Gary, S. P.; Lepri, S. T.; Vinas, A. F.; Moya, P. S.; Alexander, R.

    2016-12-01

    Strong narrow-band electromagnetic waves near the proton cyclotron frequency (fpc) have been observed extensively in the solar wind throughout the inner heliosphere. They are transverse and near-circularly polarized, and propagate in directions quasi-parallel or anti-parallel to the magnetic field. Their frequency is a few times of fpc in the spacecraft frame and a fraction of fpc in the plasma frame after removing the Doppler shift effect. These waves are left-hand (LH) or right-hand (RH) polarized in the spacecraft frame with otherwise similar characteristics except LH ones appear more often and have higher wave power. Intrinsically they can be LH polarized Alfven-cyclotron waves or RH polarized magnetosonic waves. Through the assistance of audification, we have studied the long-lasting wave events near fpc in 2005 using the high-cadence magnetic field data and well-calibrated plasma data from the Wind mission. A mixture of temperature anisotropies for core protons, beam protons, and alpha particles, as well as proton beam drift are often found for selected events of extensive waves. The wave dispersion analysis using these ion moments indicate these waves are likely to be associated with unstable Alfven-cyclotron anisotropy instability or ion beam instability, and suggest there is a mixture of Alfven-cyclotron waves and magnetosonic waves in the solar wind. Using the conjunction of Wind and ACE spacecraft when they were within 50 Earth radii of each other, we study how often the two spacecraft observe the same waves and whether there is noticeable heating for heavy ions associated with these waves.

  13. Monte Carlo simulation of cyclotron resonant scattering features

    Science.gov (United States)

    Schwarm, Fritz-Walter; Schönherr, Gabriele; Wilms, Joern

    In the regime of very high magnetic fields on the order of 10(12} mathrm{G) the electron momenta perpendicular to the field are quantized due to the discrete Landau levels populated by the electrons. Parallel to the magnetic field the electrons form a continuous momentum distribution. The seed photon continuum is generated for example by bremsstrahlung or blackbody radiation. Resonant scattering of a seed photon by an electron may excite the electron to a higher Landau level. The subsequent de-excitation of the excited electron produces additional photons close to the resonance energy. This way complex cyclotron resonant scattering features (CRSFs) are imprinted on the continuum radiation. Due to the continuous electron momentum distribution parallel to the magnetic field the scattering photon's energy and angle are mixed by Lorentz transformation to the electron rest frame in which the resonant scattering process is being carried out. Therefore synthetic spectra of cyclotron lines can not be accurately calculated analytically. CRSFs have been observed in more than a dozen accreting X-ray binaries. They provide much information about the accretion structure in the observed systems since the exact line shape is sensitive to many parameters in the column. Typical parameters are for example the geometry and the spectral properties of seed photon sources, the geometry of the column, or the magnetic field and temperature within the column. We present an overview over the Monte-Carlo approach to cyclotron line simulation and show results from our texttt{cyclosim} code. Furthermore we investigate the influence of the accretion geometry on the cyclotron line shape. Our code enables us to perform fully relativistic simulations including the correct cyclotron scattering cross sections and the possibility to cope with parameter gradients such as magnetic field, temperature, or velocity gradients within the accretion column. Using a Green's function approach these simulations

  14. Electromagnetic Cyclotron Waves in the Solar Wind: Wind Observation and Wave Dispersion Analysis

    Science.gov (United States)

    Jian, L. K.; Moya, P. S.; Vinas, A. F.; Stevens, M.

    2016-01-01

    Wind observed long-lasting electromagnetic cyclotron waves near the proton cyclotron frequency on 11 March 2005, in the descending part of a fast wind stream. Bi-Maxwellian velocity distributions are fitted for core protons, beam protons, and alpha-particles. Using the fitted plasma parameters we conduct kinetic linear dispersion analysis and find ion cyclotron and/or firehose instabilities grow in six of 10 wave intervals. After Doppler shift, some of the waves have frequency and polarization consistent with observation, thus may be correspondence to the cyclotron waves observed.

  15. Comparison of neutron fluxes in an 18-MeV unshielded cyclotron room and a 16.5-MeV self-shielded cyclotron room.

    Science.gov (United States)

    Fujibuchi, Toshioh; Horitsugi, Genki; Yamaguchi, Ichiro; Eto, Akihisa; Iwamoto, Yasuo; Obara, Satoshi; Iimori, Takashi; Masuda, Yoshitada; Watanabe, Hiroshi; Hatazawa, Jun

    2012-07-01

    Some medical compact cyclotrons have self-shielding to reduce neutron fluxes. Thermal neutron fluxes in an 18-MeV unshielded cyclotron room and in a 16.5-MeV self-shielded cyclotron room were evaluated. In addition, the radioactivities in concrete and metals due to thermal neutrons in the cyclotron rooms for 30 years were calculated of operation such that the sum of the ratio of the nuclide concentration to the nuclide clearance level was equal to 1. The thermal neutron flux from the unshielded cyclotron was approximately 10(2) cm(-2) s(-1), whereas that from the self-shielded cyclotron was approximately 10(2) cm(-2) s(-1). The thermal neutron fluxes for concrete, stainless steel, vessel steel, and aluminum that reached their clearance levels were 9.80 × 10(4), 2.17 × 10(3), 1.87 × 10(4), and 2.41 × 10(5) cm(-2) s(-1), respectively. The specific activities in the cyclotron room were found to be sufficiently below the clearance level when the self-shield was employed.

  16. Land-use evaluation for sustainable construction in a protected area: A case of Sara mountain national park.

    Science.gov (United States)

    Ristić, Vladica; Maksin, Marija; Nenković-Riznić, Marina; Basarić, Jelena

    2018-01-15

    The process of making decisions on sustainable development and construction begins in spatial and urban planning when defining the suitability of using land for sustainable construction in a protected area (PA) and its immediate and regional surroundings. The aim of this research is to propose and assess a model for evaluating land-use suitability for sustainable construction in a PA and its surroundings. The methodological approach of Multi-Criteria Decision Analysis was used in the formation of this model and adapted for the research; it was combined with the adapted Analytical hierarchy process and the Delphi process, and supported by a geographical information system (GIS) within the framework of ESRI ArcGIS software - Spatial analyst. The model is applied to the case study of Sara mountain National Park in Kosovo. The result of the model is a "map of integrated assessment of land-use suitability for sustainable construction in a PA for the natural factor". Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Practical experience and challenges in the operation of medical cyclotron.

    Science.gov (United States)

    Kumar, Rajeev; Sonkawade, Rajendra G; Pandey, Anil K; Tripathi, Madhavi; Damle, Nishikant A; Kumar, Praveen; Bal, Chandra S

    2017-01-01

    The aim of this article was to share 10 years of operational experience of medical cyclotron and to provide working knowledge on the same. This experience has helped us gain working knowledge on cyclotron operation with practical points, which may help in improving F yield, minimizing the breakdown time, and help in the prevention of the occurrence of unusual events. Our facility has a self-shielded radioisotope delivery system eclipse 111 medical cyclotron with an 11 MeV proton beam in use for the past 10 years to produce positron emitters - namely, F, N, and F-2 gas - for PET imaging. During F production, we have followed a set protocol comprising the following: monitoring target pressure, rinsing the target with O water just immediately after bombardment, ion source feedback, radiofrequency (RF) feedback, and recording any unusual events that occurred during the operation. Besides this, enrichment of O water, target volume, target current, energy of the beam, variation in argon pressure on the target, bombardment duration, target status (new or old target or total number of previous bombardments on the same target), status of the delivery lines from target to the radiochemistry module (old or new) were also recorded. Rinsing with O water immediately after bombardment increases the life of the target and delivery line. The frequent problems encountered were with the ion source, RF, and target foil rupture. These problems were solved by rebuilding the ion source, changing the fuse of RF, and rebuilding the target. F yield can be increased by rinsing with O water immediately after bombardment. The effect of target leak - that is, rupture of vacuum window - can be avoided by immediate stoppage of bombardment.

  18. Electromagnetic waves near the proton cyclotron frequency: Stereo observations

    Energy Technology Data Exchange (ETDEWEB)

    Jian, L. K. [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); Wei, H. Y.; Russell, C. T. [Institute of Geophysics and Planetary Physics, University of California, Los Angeles, CA 90095 (United States); Luhmann, J. G. [Space Science Laboratory, University of California, Berkeley, CA 94720 (United States); Klecker, B. [Max-Planck-Institut für Extraterrestrische Physik, D-85741 Garching (Germany); Omidi, N. [Solana Scientific Inc., Solana Beach, CA 92075 (United States); Isenberg, P. A. [Institute for the Study of Earth, Oceans, and Space, University of New Hampshire, Durham, NH 03824 (United States); Goldstein, M. L.; Figueroa-Viñas, A. [Heliophysics Science Division, NASA Goddard Space Flight Center, MD 20771 (United States); Blanco-Cano, X., E-mail: lan.jian@nasa.gov [Instituto de Geofisica, Universidad Nacional Autónoma de México, Coyoacán D.F. (Mexico)

    2014-05-10

    Transverse, near-circularly polarized, parallel-propagating electromagnetic waves around the proton cyclotron frequency were found sporadically in the solar wind throughout the inner heliosphere. They could play an important role in heating and accelerating the solar wind. These low-frequency waves (LFWs) are intermittent but often occur in prolonged bursts lasting over 10 minutes, named 'LFW storms'. Through a comprehensive survey of them from Solar Terrestrial Relations Observatory A using dynamic spectral wave analysis, we have identified 241 LFW storms in 2008, present 0.9% of the time. They are left-hand (LH) or right-hand (RH) polarized in the spacecraft frame with similar characteristics, probably due to Doppler shift of the same type of waves or waves of intrinsically different polarities. In rare cases, the opposite polarities are observed closely in time or even simultaneously. Having ruled out interplanetary coronal mass ejections, shocks, energetic particles, comets, planets, and interstellar ions as LFW sources, we discuss the remaining generation scenarios: LH ion cyclotron instability driven by greater perpendicular temperature than parallel temperature or by ring-beam distribution, and RH ion fire hose instability driven by inverse temperature anisotropy or by cool ion beams. The investigation of solar wind conditions is compromised by the bias of the one-dimensional Maxwellian fit used for plasma data calibration. However, the LFW storms are preferentially detected in rarefaction regions following fast winds and when the magnetic field is radial. This preference may be related to the ion cyclotron anisotropy instability in fast wind and the minimum in damping along the radial field.

  19. Cyclotron facilities in Brazil: Current status and licensing aspects

    Energy Technology Data Exchange (ETDEWEB)

    Facure, A.; Carvalho, S.M.; Di Prinzio, R.; Silveira, C.S.; Gasparian, P.B.R.; Franca, W.F., E-mail: facure@cnen.gov.br [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)

    2017-09-01

    Positron Emission Tomography (PET) is a highly sensitive and accurate nuclear medicine imaging technology but the major problem of this technique is the use of radioisotopes with short half-life, less than two hours. The production and selling of short half-life radioisotopes used to be monopoly of the Brazilian Government. In 2006, a Constitutional Amendment revoked the state monopoly due to the need for the use of short half-life radioisotopes in nuclear medicine centers very far from the government production facilities. The aim of this study is to describe the current status of short half-life radioisotopes production in Brazil and discuss some licensing process. In Brazil, as has been occurring worldwide, the number of nuclear medicine centers is increasing. Currently there are 123 services performing PET scans in Brazil. There are 14 cyclotrons operating in Brazil. The type of licensing process conducted in Brazil does not take into account the population density of each state, with a free competition model being adopted. Because of this there is a lot of equipment concentrated in the Southeast and no cyclotrons operating in the Northern part of the country. One of the biggest obstacles during the licensing process is the designation of qualified personnel as operation workers and radiation safety officers. The number of cyclotron accelerators and PET/CT equipment increased in recent years. However, a number of external factors such as the distance from the nuclear medicine centers, and qualified personnel have proved crucial for the economic viability of this type of facility. (author)

  20. Glow plasma trigger for electron cyclotron resonance ion sources.

    Science.gov (United States)

    Vodopianov, A V; Golubev, S V; Izotov, I V; Nikolaev, A G; Oks, E M; Savkin, K P; Yushkov, G Yu

    2010-02-01

    Electron cyclotron resonance ion sources (ECRISs) are particularly useful for nuclear, atomic, and high energy physics, as unique high current generators of multicharged ion beams. Plasmas of gas discharges in an open magnetic trap heated by pulsed (100 micros and longer) high power (100 kW and higher) high-frequency (greater than 37.5 GHz) microwaves of gyrotrons is promising in the field of research in the development of electron cyclotron resonance sources for high charge state ion beams. Reaching high ion charge states requires a decrease in gas pressure in the magnetic trap, but this method leads to increases in time, in which the microwave discharge develops. The gas breakdown and microwave discharge duration becomes greater than or equal to the microwave pulse duration when the pressure is decreased. This makes reaching the critical plasma density initiate an electron cyclotron resonance (ECR) discharge during pulse of microwave gyrotron radiation with gas pressure lower than a certain threshold. In order to reduce losses of microwave power, it is necessary to shorten the time of development of the ECR discharge. For fast triggering of ECR discharge under low pressure in an ECRIS, we initially propose to fill the magnetic trap with the plasmas of auxiliary pulsed discharges in crossed ExB fields. The glow plasma trigger of ECR based on a Penning or magnetron discharge has made it possible not only to fill the trap with plasma with density of 10(12) cm(-3), required for a rapid increase in plasma density and finally for ECR discharge ignition, but also to initially heat the plasma electrons to T(e) approximately = 20 eV.

  1. Experimental monitoring of ozone production in a PET cyclotron facility

    Energy Technology Data Exchange (ETDEWEB)

    Zanibellato, L. [Department of Energetic, Nuclear and Environmental Control, University of Bologna (Italy); Cicoria, G.; Pancaldi, D. [Department of Medical Physics, University Hospital ' S.Orsola-Malpighi' , Bologna (Italy); Boschi, S. [PET Radiopharmacy Unit, Department of Nuclear Medicine, University Hospital ' S.Orsola-Malpighi' , Bologna (Italy); Mostacci, D. [Department of Energetic, Nuclear and Environmental Control, University of Bologna (Italy); Marengo, M., E-mail: marengo@med.unibo.i [Department of Medical Physics, University Hospital ' S.Orsola-Malpighi' , Bologna (Italy)

    2010-10-15

    Ozone produced from radiolytic processes was investigated as a possible health hazard in the working environment at the University Hospital 'S.Orsola-Malpighi' PET facility. Intense radiation fields can generate ozone, known to be the most toxic gas produced by ionizing radiation around a particle accelerator. To evaluate ozone concentration in air, two different measurement campaigns were conducted with passive diffusion detectors. Comparison of the results with the concentration limits recommended by American Conference of Governmental Industrial Hygienists (ACGIH) demonstrated that ozone poses no health hazard to workers around a biomedical cyclotron.

  2. A new EMIS facility at the Tohoku University cyclotron

    Science.gov (United States)

    Fujioka, M.; Shinozuka, T.; Tanaka, E.; Arai, Y.; Hayashibe, S.; Ishimatsu, T.

    1981-07-01

    An EMIS facility has begun operation at one of the beam lines of a multipurpose cyclotron of K = 50 MeV. The separator is of a Scandinavian type of 55° deflection and 1500 mm dispersion, and is equipped with three beam-transport lines to which are connected a tape-transport system for ISOL study, a retardation system for implantation work and an optical spectrometer for surface analysis. The status and developments of this facility are reported here for the first time.

  3. Coaxial ring cyclotron as a perspective nuclear power engineering machine

    CERN Document Server

    Tumanyan, A R; Mkrtchyan, R L; Amatuni, T A; Avakian, R O; Khudaverdian, A G

    1995-01-01

    Coaxial Ring Cyclotron (CRC) is described, and its main advantages, such as simple injection technique, several injected beams summation option, high efficiency, are considered. The proposed proton accelerator is a perspective machine for the solution of the main problems of the present day nuclear power engineering as well as for the next-generation nuclear power plants, representing a combination of subcritical reactors and particle accelerators. The possibility of installation of CRCs into ring accelerators with an average diameter from 60 to 100m, e.g., the Yerevan electron synchrotron, is considered.

  4. Spot-welding solid targets for high current cyclotron irradiation

    Science.gov (United States)

    Ellison, Paul A.; Valdovinos, Hector F.; Graves, Stephen A.; Barnhart, Todd E.; Nickles, Robert J.

    2016-01-01

    Zirconium-89 finds broad application for use in positron emission tomography. Its cyclotron production has been limited by the heat transfer from yttrium targets at high beam currents. A spot welding technique allows a three-fold increase in beam current, without affecting 89Zr quality. An yttrium foil, welded to a jet-cooled tantalum support base accommodates a 50 μA proton beam degraded to 14 MeV. The resulting activity yield of 48 ± 4 MBq/(μA·hr) now extends the outreach of 89Zr for a broader distribution. PMID:27771445

  5. Calibration of electron cyclotron emission radiometer for KSTAR.

    Science.gov (United States)

    Kogi, Y; Jeong, S H; Lee, K D; Akaki, K; Mase, A; Kuwahara, D; Yoshinaga, T; Nagayama, Y; Kwon, M; Kawahata, K

    2010-10-01

    We developed and installed an electron cyclotron emission radiometer for taking measurements of Korea Superconducting Tokamak Advanced Research (KSTAR) plasma. In order to precisely measure the absolute value of electron temperatures, a calibration measurement of the whole radiometer system was performed, which confirmed that the radiometer has an acceptably linear output signal for changes in input temperature. It was also found that the output power level predicted by a theoretical calculation agrees with that obtained by the calibration measurement. We also showed that the system displays acceptable noise-temperature performance around 0.23 eV.

  6. Ion cyclotron resonance heating system in the RT-1 magnetospheric plasma

    Science.gov (United States)

    Nishiura, M.; Kawazura, Y.; Yoshida, Z.; Kenmochi, N.; Yano, Y.; Saitoh, H.; Yamasaki, M.; Mushiake, T.; Kashyap, A.; Takahashi, N.; Nakatsuka, M.; Fukuyama, A.

    2017-08-01

    We have developed an ion cyclotron resonance frequency (ICRF) heating system for the Ring Trap 1 (RT-1) magnetospheric device. We excite slow waves from the polar region of the dipole magnetic field. The target helium plasma is produced by electron cyclotron heating. The electrons comprise high-temperature (>10 keV) and low-temperature (wave electric field in the plasma.

  7. Quantum oscillation of the cyclotron mass in two-dimensional electron systems in silicon

    NARCIS (Netherlands)

    Kaesen, K.F.; Huber, A; Lorenz, H.; Kotthaus, J.P.; Bakker, S.; Klapwijk, T.M

    1996-01-01

    The cyclotron resonance of two-dimensional electron systems in silicon metal-oxide-semiconductor devices is investigated for high electron densities in high magnetic fields. The cyclotron mass, extracted from the resonance frequency, shows an oscillatory behavior. The periodicity of this oscillation

  8. Periodic Beam Current Oscillations Driven by Electron Cyclotron Instabilities in ECRIS Plasmas

    OpenAIRE

    Tarvainen, Olli; Kalvas, Taneli; Koivisto, Hannu; Komppula, Jani; Kronholm, Risto; Laulainen, Janne; Izotov, I.; Mansfeld, D.; Skalyga, V.; Toivanen, V.

    2014-01-01

    Experimental observation of cyclotron instabilities in electron cyclotron resonance ion source plasma operated in cwmode is reported. The instabilities are associated with strong microwave emission and a burst of energetic electrons escaping the plasma, and explain the periodic oscillations of the extracted beam currents. The instabilities are shown to restrict the parameter space available for the optimization of high charge state ion currents.

  9. Effect of ion clouds micromotion on measured signal in Fourier transform ion cyclotron resonance: Computer simulation.

    Science.gov (United States)

    Vladimirov, Gleb; Kostyukevich, Yury; Kharybin, Oleg; Nikolaev, Eugene

    2017-08-01

    Particle-in-cell-based realistic simulation of Fourier transform ion cyclotron resonance experiments could be used to generate ion trajectories and a signal induced on the detection electrodes. It has been shown recently that there is a modulation of "reduced" cyclotron frequencies in ion cyclotron resonance signal caused by Coulomb interaction of ion clouds. In this work it was proposed to use this modulation in order to determine frequency difference between an ion of known m/z and all other ions generating signal in ion cyclotron resonance cell. It is shown that with an increase of number of ions in ion cyclotron resonance trap, the modulation index increases, which lead to a decrease in the accuracy of determination of peak intensities by super Fourier transform resolution methods such as filter diagonalization method.

  10. Reduction of axial kinetic energy induced perturbations on observed cyclotron frequency.

    Science.gov (United States)

    Kaiser, Nathan K; Weisbrod, Chad R; Webb, Brian N; Bruce, James E

    2008-04-01

    With Fourier transform ion cyclotron resonance (FTICR) mass spectrometry one determines the mass-to-charge ratio of an ion by measuring its cyclotron frequency. However, the need to confine ions to the trapping region of the ion cyclotron resonance (ICR) cell with electric fields induces deviations from the unperturbed cyclotron frequency. Additional perturbations to the observed cyclotron frequency are often attributed to changes in space charge conditions. This study presents a detailed investigation of the observed ion cyclotron frequency as a function of ion z-axis kinetic energy. In a perfect three-dimensional quadrupolar field, cyclotron frequency is independent of position within the trap. However, in most ICR cell designs, this ideality is approximated only near the trap center and deviations arise from this ideal quadrupolar field as the ion moves both radially and axially from the center of the trap. To allow differentiation between deviations in observed cyclotron frequency caused from changes in space charge conditions or differences in oscillation amplitude, ions with identical molecular weights but different axial kinetic energy, and thus amplitude of z-axis motion, were simultaneously trapped within the ICR cell. This allows one to attribute deviations in observed cyclotron frequency to differences in the average force from the radial electric field experienced by ions of different axial amplitude. Experimentally derived magnetron frequency is compared with the magnetron frequency calculated using SIMION 7.0 for ions of different axial amplitude. Electron promoted ion coherence, or EPIC, is used to reduce the differences in radial electric fields at different axial positions. Thus with the application of EPIC, the differences in observed cyclotron frequencies are minimized for ions of different axial oscillation amplitudes.

  11. Survey of Saturn electrostatic cyclotron harmonic wave intensity

    Science.gov (United States)

    Menietti, J. D.; Averkamp, T. F.; Kurth, W. S.; Ye, S.-Y.; Gurnett, D. A.; Cecconi, B.

    2017-08-01

    We conduct a survey of electrostatic electron cyclotron harmonic (ECH) emissions observed at Saturn by the radio and plasma wave science investigation on board the Cassini spacecraft. These emissions are known to be effective at interacting with electrons in the terrestrial inner magnetosphere, producing electron scattering into the loss cone and acceleration (cf. Horne and Thorne, 2000; Thorne et al., 2010). At Saturn ECH emission occurs with high probability and at strong intensity near the magnetic equator, outside the Enceladus torus in the range 5 < L < 10. Inside the inner boundary of the torus, ECH emissions are also observed near the equator and at higher latitude. Intensity levels of ECH emission are comparable to those observed at Earth, higher than Saturn chorus and Z-mode emission, and are likely to scatter electrons into the loss cone as at Earth. ECH waves are particularly intense and extend to higher harmonics within some plasma injection regions. We present results for a survey of over 8 years of Saturn data for fundamental and up to three harmonics of fce, the electron cyclotron frequency.

  12. New radionuclides production on the isochronous cyclotron U-120M

    Energy Technology Data Exchange (ETDEWEB)

    Stursa, J.; Cihak, M.; Krivanek, M.; Kucera, J.; Lacman, J. [Nuclear Physics Institute, Prague (Czech Republic)

    1999-07-01

    The production of {sup 18}F for positron emission tomography (PET) applications and manufacturing of the {sup 81}Rb for the {sup 81}Rb/{sup 81m}Kr radionuclidic generator (used in lung ventilation studies) have been introduced as a new program of the twenty year old cyclotron U-120M(K=40, A/Z=1-2.8). The cyclotron conversion from positive to H/{sup -}D{sup -} accelerating regimes and the extraction by means of stripping were necessary for obtaining sufficiently high beam intensities. Two possible solutions of H{sup -} gain - either from the external high intensive (1 mA DC) old TRIUMF CUSP ion source or from the internal ion source with a cold cathode developed in our laboratory - are described. Axial injector characteristics for H{sup -} currents up to 1 mA together with optimizing the central region, the ion extraction system and upgrade of the vacuum system are presented. The realization of the enriched H{sub 2}O{sup 18} target, its setting into operation and the first results of {sup 18}F production (average yields {approx} 2 GBq/{mu}A. hour at EOB) are briefly discussed. (authors)

  13. Hyperproduction of Alpha-Hemolysin in a sigB Mutant Is Associated with Elevated SarA Expression in Staphylococcus aureus

    Science.gov (United States)

    Cheung, Ambrose L.; Chien, Yueh-tyng; Bayer, Arnold S.

    1999-01-01

    To evaluate the role of SigB in modulating the expression of virulence determinants in Staphylococcus aureus, we constructed a sigB mutant of RN6390, a prototypic S. aureus strain. The mutation in the sigB gene was confirmed by the absence of the SigB protein in the mutant on an immunoblot as well as the failure of the mutant to activate ςB-dependent promoters (e.g., the sarC promoter) of S. aureus. Phenotypic analysis indicated that both alpha-hemolysin level and fibrinogen-binding capacity were up-regulated in the mutant strain compared with the parental strain. The increase in fibrinogen-binding capacity correlated with enhanced expression of clumping factor and coagulase on immunoblots. The effect of the sigB mutation on the enhanced expression of the alpha-hemolysin gene (hla) was primarily transcriptional. Upon complementation with a plasmid containing the sigB gene, hla expression returned to near parental levels in the mutant. Detailed immunoblot analysis as well as a competitive enzyme-linked immunosorbent assay of the cell extract of the sigB mutant with anti-SarA monoclonal antibody 1D1 revealed that the expression of SarA was higher in the mutant than in the parental control. Despite an elevated SarA level, the transcription of RNAII and RNAIII of the agr locus remained unaltered in the sigB mutant. Because of a lack of perturbation in agr, we hypothesize that inactivation of sigB leads to increased expression of SarA which, in turn, modulates target genes via an agr-independent but SarA-dependent pathway. PMID:10024579

  14. Cyclotrons with fast variable and/or multiple energy extraction

    Directory of Open Access Journals (Sweden)

    C. Baumgarten

    2013-10-01

    Full Text Available We discuss the possibility in principle of stripping extraction in combination with reverse bends in isochronous separate-sector cyclotrons (and/or fixed field alternating gradient accelerators. If one uses reverse bends between the sectors (instead of or in combination with drifts and places stripper foils at the sector exit edges, the stripped beam has a reduced bending radius and it should be able to leave the cyclotron within the range of the valley—even if the beam is stripped at less than full energy. We are especially interested in stripping of H_{2}^{+}, as it doubles the charge to mass ratio of the ions. However the method could be applied to other ions or ionized molecules as well. For the production of proton beams by stripping extraction of an H_{2}^{+} beam, we discuss possible designs for three types of machines: First, a low-energy cyclotron for the simultaneous production of several beams at multiple energies—for instance 15, 30, and 70 MeV—thus allowing beam delivery on several isotope production targets. In this case it can be an advantage to have a strong energy dependence of the direction of the extracted beam. Second, we consider a fast variable-energy proton machine for cancer therapy that should allow extraction (of the complete beam at all energies in the range of about 70 MeV to about 250 MeV into the same beam line. Third, we consider a high-intensity high-energy machine, where the main design goals are extraction with low losses, low activation of components, and high reliability. Especially if such a machine is considered for an accelerator driven system (ADS, this extraction mechanism has advantages: Beam trips by the failure of electrostatic elements could be avoided and the turn separation would be less critical, which allows operation at lower main cavity voltages. This would in turn reduce the number of rf trips. The price that has to be paid for these advantages is an increase in size and/or field

  15. Technical note: building a combined cyclotron and MRI facility: implications for interference.

    Science.gov (United States)

    Hofman, Mark B M; Kuijer, Joost P A; de Ridder, Jan Willem; Perk, Lars R; Verdaasdonk, Rudolf M

    2013-01-01

    With the introduction of hybrid PET∕MRI systems, it has become more likely that the cyclotron and MRI systems will be located close to each other. This study considered the interference between a cyclotron and a superconducting MRI system. Interactions between cyclotrons and MRIs are theoretically considered. The main interference is expected to be the perturbation of the magnetic field in the MRI due to switching on or off the magnetic field of the cyclotron. MR imaging is distorted by a dynamic spatial gradient of an external inplane magnetic field larger than 0.5-0.04 μT∕m, depending on the specific MR application. From the design of a cyclotron, it is expected that the magnetic fringe field at large distances behaves as a magnetic dipolar field. This allows estimation of the full dipolar field and its spatial gradients from a single measurement. Around an 18 MeV cyclotron (Cyclone, IBA), magnetic field measurements were performed on 5 locations and compared with calculations based upon a dipolar field model. At the measurement locations the estimated and measured values of the magnetic field component and its spatial gradients of the inplane component were compared, and found to agree within a factor 1.1 for the magnetic field and within a factor of 1.5 for the spatial gradients of the field. In the specific case of the 18 MeV cyclotron with a vertical magnetic field and a 3T superconducting whole body MR system, a minimum distance of 20 m has to be considered to prevent interference. This study showed that a dipole model is sufficiently accurate to predict the interference of a cyclotron on a MRI scanner, for site planning purposes. The cyclotron and a whole body MRI system considered in this study need to be placed more than 20 m apart, or magnetic shielding should be utilized.

  16. Technical Note: Building a combined cyclotron and MRI facility: Implications for interference

    Energy Technology Data Exchange (ETDEWEB)

    Hofman, Mark B. M.; Kuijer, Joost P. A.; Ridder, Jan Willem de; Perk, Lars R.; Verdaasdonk, Rudolf M. [Physics and Medical Technology, VU University Medical Center, Amsterdam 1007 MB (Netherlands) and BV Cyclotron VU, Amsterdam 1081HV (Netherlands)

    2013-01-15

    Purpose: With the introduction of hybrid PET/MRI systems, it has become more likely that the cyclotron and MRI systems will be located close to each other. This study considered the interference between a cyclotron and a superconducting MRI system. Methods: Interactions between cyclotrons and MRIs are theoretically considered. The main interference is expected to be the perturbation of the magnetic field in the MRI due to switching on or off the magnetic field of the cyclotron. MR imaging is distorted by a dynamic spatial gradient of an external inplane magnetic field larger than 0.5-0.04 {mu}T/m, depending on the specific MR application. From the design of a cyclotron, it is expected that the magnetic fringe field at large distances behaves as a magnetic dipolar field. This allows estimation of the full dipolar field and its spatial gradients from a single measurement. Around an 18 MeV cyclotron (Cyclone, IBA), magnetic field measurements were performed on 5 locations and compared with calculations based upon a dipolar field model. Results: At the measurement locations the estimated and measured values of the magnetic field component and its spatial gradients of the inplane component were compared, and found to agree within a factor 1.1 for the magnetic field and within a factor of 1.5 for the spatial gradients of the field. In the specific case of the 18 MeV cyclotron with a vertical magnetic field and a 3T superconducting whole body MR system, a minimum distance of 20 m has to be considered to prevent interference. Conclusions: This study showed that a dipole model is sufficiently accurate to predict the interference of a cyclotron on a MRI scanner, for site planning purposes. The cyclotron and a whole body MRI system considered in this study need to be placed more than 20 m apart, or magnetic shielding should be utilized.

  17. Experiments on ion cyclotron damping at the deuterium fourth harmonic in DIII-D

    Energy Technology Data Exchange (ETDEWEB)

    Pinsker, R.I.; Petty, C.C. [General Atomics, San Diego, CA (United States); Baity, F.W. [Oak Ridge National Lab., TN (United States); Bernabei, S.; Greenough, N. [Princeton Plasma Physics Lab., NJ (United States); Heidbrink, W.W. [Univ. of California, Irvine, CA (United States); Mau, T.K. [Univ. of California, San Diego, CA (United States); Porkolab, M. [Massachusetts Inst. of Tech., Cambridge, MA (United States)

    1999-05-01

    Absorption of fast Alfven waves by the energetic ions of an injected beam is evaluated in the DIII-D tokamak. Ion cyclotron resonance absorption at the fourth harmonic of the deuteron cyclotron frequency is observed with deuterium neutral beam injection (f = 60 MHz, B{sub T} = 1.9 T). Enhanced D-D neutron rates are evidence of absorption at the Doppler-shifted cyclotron resonance. Characteristics of global energy confinement provide further proof of substantial beam acceleration by the rf. In many cases, the accelerated deuterons cause temporary stabilization of the sawtooth (monster sawteeth), at relatively low rf power levels of {approximately}1 MW.

  18. Analysis for liquid cryogen spillage in the superconducting cyclotron building at VECC

    CERN Document Server

    Roy S ,; Pal, G; Bhandari, R K

    2009-01-01

    The cryogenic system uses liquid helium and liquid nitrogen to cool the superconducting cyclotron magnet and its cryopanels. In order to assess safety scenarios subsequent to an unusual leakage of cryogens from the system, a deterministic analysis has been carried out to estimate the variation of oxygen concentration with time at several locations of superconducting cyclotron building. The entire process is simulated assuming evaporated cryogens mixes instantaneously with air in the confined space, the ventilation system of the cyclotron building is operational, fresh air continuously enters the confined volume and mixes instantaneously with air in the confined space.

  19. Numerical model of electron cyclotron resonance ion source

    Directory of Open Access Journals (Sweden)

    V. Mironov

    2015-12-01

    Full Text Available Important features of the electron cyclotron resonance ion source (ECRIS operation are accurately reproduced with a numerical code. The code uses the particle-in-cell technique to model the dynamics of ions in ECRIS plasma. It is shown that a gas dynamical ion confinement mechanism is sufficient to provide the ion production rates in ECRIS close to the experimentally observed values. Extracted ion currents are calculated and compared to the experiment for a few sources. Changes in the simulated extracted ion currents are obtained with varying the gas flow into the source chamber and the microwave power. Empirical scaling laws for ECRIS design are studied and the underlying physical effects are discussed.

  20. The Electron Cyclotron Resonance Light Source Assembly of PTB - ELISA

    CERN Document Server

    Gruebling, P; Ulm, G

    1999-01-01

    In the radiometry laboratory of the Physikalisch-Technische,Bundesanstalt at the Berlin electron storage ring BESSY I, radiation sources for radiometric applications in industry and basic research in the vacuum ultraviolet (VUV) spectral range are developed, characterized and calibrated. Established sources such as deuterium lamps, Penning and hollow cathode discharge sources have limited spectral ranges and in particular their stability and life time suffers from the erosion of the cathode material. To overcome these limitations we have developed a radiation source based on the principle of the electron cyclotron resonance ion source. ELISA is a 10 GHz monomode source with a compact design featuring a tunable cavity and axially positionable permanent magnets. The radiation emission of the source can be detected simultaneously in the VUV and X-ray spectral range via a toroidal grating monochromator and a Si(Li)-detector. The special design of the source allows spectroscopic investigations of the plasma in dep...

  1. One-electron quantum cyclotron (and implications for cold antihydrogen)

    CERN Document Server

    Gabrielse, G; Odom, B; D'Urso, B

    2001-01-01

    Quantum jumps between Fock states of a one-electron oscillator reveal the quantum limit of a cyclotron accelerator. The states live for seconds when spontaneous emission is inhibited by a factor of 140 within a cylindrical Penning trap cavity. Averaged over hours the oscillator is in thermal equilibrium with black-body photons in the cavity. At 80 mK, quantum jumps occur only when resonant microwave photons are introduced into the cavity, opening a route to improved measurements of the magnetic moments of the electron and positron. The temperature demonstrated is about 60 times lower than the 4.2 K temperature at which charged elementary particles were previously stored. Implications for the production of cold antihydrogen are discussed. (21 refs).

  2. Electromagnetic ion/ion cyclotron instability - Theory and simulations

    Science.gov (United States)

    Winske, D.; Omidi, N.

    1992-01-01

    Linear theory and 1D and 2D hybrid simulations are employed to study electromagnetic ion/ion cyclotron (EMIIC) instability driven by the relative streaming of two field-aligned ion beams. The characteristics of the instability are studied as a function of beam density, propagation angle, electron-ion temperature ratios, and ion beta. When the propagation angle is near 90 deg the EMIIC instability has the characteristics of an electrostatic instability, while at smaller angles electromagnetic effects play a significant role as does strong beam coupling. The 2D simulations point to a narrowing of the wave spectrum and accompanying coherent effects during the linear growth stage of development. The EMIIC instability is an important effect where ion beta is low such as in the plasma-sheet boundary layer and upstream of slow shocks in the magnetotail.

  3. Why NASA and the Space Electronics Community Cares About Cyclotrons

    Science.gov (United States)

    LaBel, Kenneth A.

    2017-01-01

    NASA and the space community are faced with the harsh reality of operating electronic systems in the space radiation environment. Systems need to work reliably (as expected for as long as expected) and be available during critical operations such as docking or firing a thruster. This talk will provide a snapshot of the import of ground-based research on the radiation performance of electronics. Discussion topics include: 1) The space radiation environment hazard, 2) Radiation effects on electronics, 3) Simulation of effects with cyclotrons (and other sources), 4) Risk prediction for space missions, and, 5) Real-life examples of both ground-based testing and space-based anomalies and electronics performance. The talk will conclude with a discussion of the current state of radiation facilities in North America for ground-based electronics testing.

  4. A LabVIEW based cyclotron magnetic field mapping system

    Energy Technology Data Exchange (ETDEWEB)

    Marti, F.; Johnson, P. [NSCL, Michigan State University, East Lansing, MI (United States)

    1999-07-01

    This paper describes the application of National Instruments LabVIEW to the NSCL K500 magnet mapping, as part of the Coupled Cyclotron Upgrade. LabVIEW provides a fast development environment for hardware control from a PC running Windows NT. The PC and LabVIEW environment allow non-professional computer programmers to obtain a reliable and flexible system where modifications can be quickly implemented. This program supports the use of motor controllers, data acquisition cards, digital I/O modules and GPIB instruments. A complete map of 360 degrees is obtained in approximately 90 minutes, measuring 185000 field values with a spacing of 1.6 mm in radius every degree. (author)

  5. Mechanism for electron cyclotron heating of collisionless plasma

    Energy Technology Data Exchange (ETDEWEB)

    Golovanivskii, K.S.; Dugard-Jabon, V.D.; Milant' ev, V.P.

    1975-01-01

    The electron distribution with respect to transverse energy is derived for electron cyclotron resonance in a constant, homogeneous magnetic field; weak relativistic effects are taken into account. After the establishment of a steady-state distribution with groups of hot and cold electrons, no energy is pumped from the rf field to the plasma. The rf electrostatic perturbations are studied on the basis of the distribution function found; it is shown that waves of two types are unstable eigenmodes of the plasma at rest and drift waves. The growth rates for the corresponding instabilities are derived. A study is also made of the stability of right-handed circularly polarized electromagnetic wave propagating along the magnetic field. Instabilities occur at frequencies which depend on the degree of anisotropy, analogous to the case of a plasma with a temperature anisotropy.

  6. Recent developments of cyclotron produced radionuclides for nuclear cardiology

    Science.gov (United States)

    Kulkarni, P. V.; Jansen, D. E.; Corbett, J. R.

    1987-04-01

    For over a decade myocardial perfusion imaging with thallium-201, a cyclotron product, has been routinely used in clinical medicine. Recent advances have allowed the efficient production of very high purity (> 99.8%) iodine-123. New metabolically active 123I labeled radiopharmaceuticals, including alkyl and phenyl fatty acids, and norepinephrine analogs, have been developed and are undergoing clinical trials. Fab' fragments of monoclonal antibodies to cardiac myosin have been labeled with indium-111 ( 111In) and are undergoing clinical evaluation for imaging myocardial infarcts. Monoclonal antibodies to platelets, fibrin, and the thrombolytic agent, tissue plasminogen activator (TPA), have recently been labeled with 111In. Together these developments in radiotracers and instrumentation should have a significant impact on the future of cardiovascular nuclear medicine. This manuscript will discuss developments in single photon emitting radiotracers for myocardial imaging.

  7. Alternative optical concept for electron cyclotron emission imaging.

    Science.gov (United States)

    Liu, J X; Milbourne, T; Bitter, M; Delgado-Aparicio, L; Dominguez, A; Efthimion, P C; Hill, K W; Kramer, G J; Kung, C; Kubota, S; Kasparek, W; Lu, J; Pablant, N A; Park, H; Tobias, B

    2014-11-01

    The implementation of advanced electron cyclotron emission imaging (ECEI) systems on tokamak experiments has revolutionized the diagnosis of magnetohydrodynamic (MHD) activities and improved our understanding of instabilities, which lead to disruptions. It is therefore desirable to have an ECEI system on the ITER tokamak. However, the large size of optical components in presently used ECEI systems have, up to now, precluded the implementation of an ECEI system on ITER. This paper describes a new optical ECEI concept that employs a single spherical mirror as the only optical component and exploits the astigmatism of such a mirror to produce an image with one-dimensional spatial resolution on the detector. Since this alternative approach would only require a thin slit as the viewing port to the plasma, it would make the implementation of an ECEI system on ITER feasible. The results obtained from proof-of-principle experiments with a 125 GHz microwave system are presented.

  8. Data processing in Fourier transform ion cyclotron resonance mass spectrometry.

    Science.gov (United States)

    Qi, Yulin; O'Connor, Peter B

    2014-01-01

    The Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer intricately couples advanced physics, instrumentation, and electronics with chemical and particularly biochemical research. However, general understanding of the data processing methodologies used lags instrumentation, and most data processing algorithms we are familiar with in FT-ICR are not well studied; thus, professional skill and training in FT-ICR operation and data analysis is still the key to achieve high performance in FT-ICR. This review article is focused on FT-ICR data processing, and explains the procedures step-by-step for users with the goal of maximizing spectral features, such as mass accuracy, resolving power, dynamic range, and detection limits. © 2014 Wiley Periodicals, Inc.

  9. Cyclotron Resonance Gain for FIR and THz Radiation in Graphene

    CERN Document Server

    Cole, Nightvid

    2016-01-01

    A cyclotron resonance maser source using low-effective-mass conduction electrons in graphene, if successful, would allow for generation of Far Infrared (FIR) and Terahertz (THz) radiation without requiring magnetic fields running into the tens of Tesla. In order to investigate this possibility, we consider a device in which electrons are effectively injected via pumping from the valence band to the conduction band using an infrared (IR) laser source, subsequently gyrate in a magnetic field applied perpendicular to the plane of the graphene, and give rise to gain for a FIR/THz wave crossing the plane of the graphene. A set of integral expressions is derived by assuming that the non-radiative energy loss processes of the electrons can be adequately represented by a damping force proportional and antiparallel to their momentum. Minimal gain may occur at very short electron damping times of hundreds of femtoseconds.

  10. The NSCL cyclotron gas stopper – Entering commissioning

    Energy Technology Data Exchange (ETDEWEB)

    Schwarz, S. [National Superconducting Cyclotron Laboratory, East Lansing, MI (United States); Bollen, G. [Department of Physics and Astronomy, Michigan State University, East Lansing, MI (United States); Facility for Rare Isotope Beams, East Lansing, MI (United States); Chouhan, S. [Facility for Rare Isotope Beams, East Lansing, MI (United States); Das, J.J. [National Superconducting Cyclotron Laboratory, East Lansing, MI (United States); Green, M. [Facility for Rare Isotope Beams, East Lansing, MI (United States); Magsig, C. [National Superconducting Cyclotron Laboratory, East Lansing, MI (United States); Morrissey, D.J. [National Superconducting Cyclotron Laboratory, East Lansing, MI (United States); Department of Chemistry, Michigan State University, East Lansing, MI 48824 (United States); Ottarson, J.; Sumithrarachchi, C. [National Superconducting Cyclotron Laboratory, East Lansing, MI (United States); Villari, A.C.C.; Zeller, A. [Facility for Rare Isotope Beams, East Lansing, MI (United States)

    2016-06-01

    Linear gas stopping cells have been used successfully at NSCL to slow down ions produced by projectile fragmentation from the 100 MeV/u to the keV energy range. These ‘stopped beams’ have first been used for low-energy high precision experiments and more recently for NSCLs re-accelerator ReA. A gas-filled reverse cyclotron is currently under construction by the NSCL to complement the existing stopping cells: Due to its extended stopping length, efficient stopping and fast extraction is expected even for light and medium-mass ions, which are difficult to thermalize in linear gas cells. The device is based on a 2.6 T maximum-field cyclotron-type magnet to confine the injected beam while it is slowed down in ≈100 mbar of LN{sub 2}-temperature helium gas. Once thermalized, the beam will be transported to the center of the device by a traveling-wave RF-carpet system, extracted along the symmetry axis with an ion conveyor and miniature RF-carpets, and accelerated to a few tens of keV of energy for delivery to the users. The superconducting magnet has been constructed on a 60 kV platform and energized to its nominal field strength. The magnet’s two cryostats use 3 cryo-refrigerators each and liquid-nitrogen cooled thermal shields to cool the coil pair to superconductivity. This concept, chosen not to have to rely on external liquid helium, has been working well. Measurements of axial and radial field profiles confirm the field calculations. The individual RF-ion guiding components for low-energy ion transport through the device have been tested successfully. The beam stopping chamber with its 0.9 m-diameter RF carpet system and the ion extraction system are being prepared for installation inside the magnet for low-energy ion transport tests.

  11. A Tuning Method for Electrically Compensated Ion Cyclotron Resonance Mass Spectrometer Traps

    Science.gov (United States)

    Brustkern, Adam M.; Rempel, Don L.; Gross, Michael L.

    2010-01-01

    We describe a method for tuning electrically compensated ion cyclotron resonance (ICR) traps by tracking the observed cyclotron frequency of an ion cloud at different oscillation mode amplitudes. Although we have used this method to tune the compensation voltages of a custom-built electrically compensated trap, the approach is applicable to other designs that incorporate electrical compensation. To evaluate the effectiveness of tuning, we examined the frequency shift as a function of cyclotron orbit size at different z-mode oscillation amplitudes. The cyclotron frequencies varied by ~ 12 ppm for ions with low z-mode oscillation amplitudes compared to those with high z-mode amplitudes. This frequency difference decreased to ~1 ppm by one iteration of trap tuning. PMID:20060743

  12. Realistic simulations of a cyclotron spiral inflector within a particle-in-cell framework

    Science.gov (United States)

    Winklehner, Daniel; Adelmann, Andreas; Gsell, Achim; Kaman, Tulin; Campo, Daniela

    2017-12-01

    We present an upgrade to the particle-in-cell ion beam simulation code opal that enables us to run highly realistic simulations of the spiral inflector system of a compact cyclotron. This upgrade includes a new geometry class and field solver that can handle the complicated boundary conditions posed by the electrode system in the central region of the cyclotron both in terms of particle termination, and calculation of self-fields. Results are benchmarked against the analytical solution of a coasting beam. As a practical example, the spiral inflector and the first revolution in a 1 MeV /amu test cyclotron, located at Best Cyclotron Systems, Inc., are modeled and compared to the simulation results. We find that opal can now handle arbitrary boundary geometries with relative ease. Simulated injection efficiencies and beam shape compare well with measured efficiencies and a preliminary measurement of the beam distribution after injection.

  13. Cyclotron-based nuclear science. Progress report, April 1, 1979-March 31, 1980

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-01

    Research at the cyclotron institute is summarized. These major areas are covered: nuclear structure; nuclear reactions and scattering; polarization studies; interdisciplinary nuclear science; instrumentation and systems development; and publications. (GHT)

  14. Magnetic Alfvén‐cyclotron fluctuations of anisotropic nonthermal plasmas

    National Research Council Canada - National Science Library

    Navarro, Roberto E; Muñoz, Víctor; Araneda, Jaime; Viñas, Adolfo F.‐; Moya, Pablo S; Valdivia, Juan A

    2015-01-01

    .... Here we study magnetic Alfvén‐cyclotron fluctuations propagating along a background magnetic field in a plasma composed of thermal and suprathermal protons and electrons via the fluctuation...

  15. Research of the Electron Cyclotron Emission with Vortex Property excited by high power high frequency Gyrotron

    Science.gov (United States)

    Goto, Yuki; Kubo, Shin; Tsujimura, Tohru; Takubo, Hidenori

    2017-10-01

    Recently, it has been shown that the radiation from a single electron in cyclotron motion has vortex property. Although the cyclotron emission exists universally in nature, the vortex property has not been featured because this property is normally cancelled out due to the randomness in gyro-phase of electrons and the development of detection of the vortex property has not been well motivated. In this research, we are developing a method to generate the vortex radiation from electrons in cyclotron motion with controlled gyro-phase. Electron that rotates around the uniform static magnetic field is accelerated by right-hand circular polarized (RHCP) radiation resonantly when the cyclotron frequency coincides with the applied RHCP radiation frequency. A large number of electrons can be coherently accelerated in gyro-phase by a RHCP high power radiation so that these electrons can radiate coherent emission with vortex feature. We will show that vortex radiation created by purely rotating electrons for the first time.

  16. The staphylococcal accessory regulator, SarA, is an RNA-binding protein that modulates the mRNA turnover properties of late-exponential and stationary phase Staphylococcus aureus cells

    Directory of Open Access Journals (Sweden)

    John M Morrison

    2012-03-01

    Full Text Available The modulation of mRNA turnover is gaining recognition as a mechanism by which Staphylococcus aureus regulates gene expression, but the factors that orchestrate alterations in transcript degradation are poorly understood. In that regard, we previously found that 138 mRNA species, including the virulence factors protein A (spa and collagen binding protein (cna, are stabilized in a sarA-dependent manner during exponential phase growth, suggesting that SarA protein may directly or indirectly effect the RNA turnover properties of these transcripts. Herein, we expanded our characterization of the effects of sarA on mRNA turnover during late exponential and stationary phases of growth. Results revealed that the locus affects the RNA degradation properties of cells during both growth phases. Further, using gel mobility shift assays and RIP-ChIP, it was found that SarA protein is capable of binding mRNA species that it stabilizes both in vitro and within bacterial cells. Taken together, these results suggest that SarA post-transcriptionally regulates S. aureus gene expression in a manner that involves binding to and consequently altering the mRNA turnover properties of target transcripts.

  17. Measurement of ion cyclotron emissions by use of ICRF heating antennas in LHD

    Energy Technology Data Exchange (ETDEWEB)

    Saito, K. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan)], E-mail: saito@nifs.ac.jp; Kasahara, H.; Seki, T.; Kumazawa, R.; Mutoh, T.; Watanabe, T.; Shimpo, F.; Nomura, G.; Osakabe, M. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan); Ichimura, M. [Tsukuba University, Plasma Research Center, Tsukuba, Ibaraki 305-8577 (Japan); Higaki, H. [Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8530 (Japan); Komori, A. [National Institute for Fusion Science, Toki, Gifu 509-5292 (Japan)

    2009-06-15

    Ion cyclotron emissions (ICEs) were clearly detected in the Large Helical Device (LHD) during perpendicular neutral beam (NB) injection. Antennas for the ion cyclotron range of frequencies (ICRF) heating were used as probes. The frequencies of ICEs were proportional to magnetic field strength. The location of ICE excitation was a peripheral region of plasma and the source particles were lost-ions injected by the perpendicular NB.

  18. Simulation, design, and testing of a high power collimator for the RDS-112 cyclotron.

    Science.gov (United States)

    Peeples, Johanna L; Stokely, Matthew H; Poorman, Michael C; Bida, Gerald T; Wieland, Bruce W

    2015-03-01

    A high power [F-18] fluoride target package for the RDS-112 cyclotron has been designed, tested, and commercially deployed. The upgrade includes the CF-1000 target, a 1.3kW water target with an established commercial history on RDS-111/Eclipse cyclotrons, and a redesigned collimator with improved heat rejection capabilities. Conjugate heat transfer analyses were employed to both evaluate the existing collimator capabilities and design a suitable high current replacement. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Optically detected cyclotron resonance in a single GaAs/AlGaAs heterojunction

    Energy Technology Data Exchange (ETDEWEB)

    Bartsch, Gregor

    2011-09-23

    Optically detected far-infrared cyclotron resonance (FIR-ODCR) in GaAs/AlGaAs HJs is interpreted in the frame of an exciton-dissociation mechanism. It is possible to explain the ODR mechanism by an exciton drag, mediated by ballistically propagating phonons. Furthermore, very narrow resonances are presented and realistic electron mobility values can be calculated. The exceptionally narrow ODCRs allow to measure conduction-band nonparabolicity effects and resolve satellite resonances, close to the main cyclotron resonance line.

  20. Symmetry Properties of Proton Velocity Distributions: a Vlasov Simulation Study of the Ion Cyclotron Instability

    Science.gov (United States)

    Araneda, J. A.; López, R. A.; Vinas, A. F.

    2014-12-01

    The ion cyclotron instability is driven by a sufficiently large proton temperature anisotropy, generating a spectrum of counterpropagating field-aligned ion cyclotron fluctuations. In this work, we use low-noise one-dimensional electromagnetic Vlasov simulations in a magnetized and collisionless plasma of fluid electrons and one ion species to study the evolution of proton velocity distributions during the thermal relaxation process. Special attention is given to deviations from initial bi-Maxwellian shapes.

  1. Determination of Magnet Specification of 13 MeV Proton Cyclotron Based on Opera 3D

    Directory of Open Access Journals (Sweden)

    Taufik

    2014-08-01

    Full Text Available The magnet is one of the main components of a cyclotron, used to form a circular particle beam trajectories and to provide focusing of the beam. To support the mastery of 13-MeV proton cyclotron technologies, cyclotron magnet design must be done to satisfy cyclotron magnet requirements. This research was conducted by studying important parameters in designing the cyclotron magnet which is then used to determine the design requirements. The magnet design was based on the results of a 3D simulation using Opera 3D software. Opera 3D is a software developed by Cobham plc to solve physical problems in 3D such as magnetostatic using finite element methods. The simulation started by drawing a 3D model of the magnet using a modeler, followed by magnetic field calculations by Tosca module in the Opera 3D software. Simulation results were analyzed with the Genspeo software to determine whether the parameters of the cyclotron magnet have met design requirements. The results indicate that the magnet design satisfied the cyclotron magnet design requirement, that B in the median plane of the magnetic pole approached the isochronous curve, providing axial and radial focusing beam, crossing the resonance line at vr = 1 when the particle energy is low and the particle energy is more than 13 MeV, and lead to small enough phase shift of about 13°. The dimension of the cyclotron magnet is 1.96 m × 1.30 m × 1.21 m; its weight is 17.3 ton; its coil current is 88,024 ampere-turn; its center magnetic field is 1.27479 T; its maximum magnetic field is 1.942116 T; its minimum magnetic field is 0.7689 T; its valley gap is 120 mm; its hill gaps are 40 to 50.78 mm; and its hill angles are 35° to 44°.to 44°

  2. Bi-directional Alfv\\'en Cyclotron Instabilities in the Mega-Amp Spherical Tokamak

    CERN Document Server

    Sharapov, S E; Akers, R; Ayed, N Ben; Cecconello, M; Cook, J W C; Cunningham, G; Verwichte, E; Tea, the MAST

    2014-01-01

    Alfv\\'en cyclotron instabilities excited by velocity gradients of energetic beam ions were investigated in MAST experiments with super-Alfv\\'enic NBI over a wide range of toroidal magnetic fields from ~0.34 T to ~0.585 T. In MAST discharges with high magnetic field, a discrete spectrum of modes in the sub-cyclotron frequency range is excited toroidally propagating counter to the beam and plasma current (toroidal mode numbers n < 0).

  3. Coupling of electrostatic ion cyclotron and ion acoustic waves in the solar wind

    Energy Technology Data Exchange (ETDEWEB)

    Sreeraj, T., E-mail: sreerajt13@iigs.iigm.res.in [Indian Institute of Geomagnetism, Navi Mumbai (India); Singh, S. V., E-mail: satyavir@iigs.iigm.res.in; Lakhina, G. S., E-mail: gslakhina@gmail.com [Indian Institute of Geomagnetism, Navi Mumbai (India); University of the Western Cape, Bellville 7535, Capetown (South Africa)

    2016-08-15

    The coupling of electrostatic ion cyclotron and ion acoustic waves is examined in three component magnetized plasma consisting of electrons, protons, and alpha particles. In the theoretical model relevant to solar wind plasma, electrons are assumed to be superthermal with kappa distribution and protons as well as alpha particles follow the fluid dynamical equations. A general linear dispersion relation is derived for such a plasma system which is analyzed both analytically and numerically. For parallel propagation, electrostatic ion cyclotron (proton and helium cyclotron) and ion acoustic (slow and fast) modes are decoupled. For oblique propagation, coupling between the cyclotron and acoustic modes occurs. Furthermore, when the angle of propagation is increased, the separation between acoustic and cyclotron modes increases which is an indication of weaker coupling at large angle of propagation. For perpendicular propagation, only cyclotron modes are observed. The effect of various parameters such as number density and temperature of alpha particles and superthermality on dispersion characteristics is examined in details. The coupling between various modes occurs for small values of wavenumber.

  4. Influence of injection beam emittance on beam transmission efficiency in a cyclotron.

    Science.gov (United States)

    Kurashima, Satoshi; Kashiwagi, Hirotsugu; Miyawaki, Nobumasa; Yoshida, Ken-Ichi; Okumura, Susumu

    2014-02-01

    The JAEA AVF cyclotron accelerates various kinds of high-energy ion beams for research in biotechnology and materials science. Beam intensities of an ion species of the order of 10(-9)-10(-6) ampere are often required for various experiments performed sequentially over a day. To provide ion beams with sufficient intensity and stability, an operator has to retune an ion source in a short time. However, the beam intensity downstream of the cyclotron rarely increases in proportion to the intensity at the ion source. To understand the cause of this beam behavior, transmission efficiencies of a (12)C(5+) beam from an electron cyclotron resonance ion source to the cyclotron were measured for various conditions of the ion source. Moreover, a feasible region for acceleration in the emittance of the injection beam was clarified using a transverse-acceptance measuring system. We confirmed that the beam emittance and profile were changed depending on the condition of the ion source and that matching between the beam emittance and the acceptance of the cyclotron was degraded. However, after fine-tuning to improve the matching, beam intensity downstream of the cyclotron increased.

  5. Nutritional Models of Experimentally-Induced Subacute Ruminal Acidosis (SARA) Differ in Their Impact on Rumen and Hindgut Bacterial Communities in Dairy Cows.

    Science.gov (United States)

    Plaizier, Jan C; Li, Shucong; Tun, Hein M; Khafipour, Ehsan

    2016-01-01

    Effects of subacute ruminal acidosis (SARA) challenges on the bacteria in rumen fluid, cecal digesta, and feces of dairy cows were determined using 16S rRNA gene pyrosequencing and real-time quantitative PCR. Six non-lactating Holstein cows with cannulas in the rumen and cecum were used in a 3 × 3 Latin square arrangement of treatments. During the first 3 wk of each experimental period, cows received a control diet containing 70% forages on a dry matter (DM) basis. In wk 4 of each period, cows received one of three diets: (1) the control diet; (2) a diet in which 34% of the dietary DM was replaced with pellets of ground wheat and barley (GBSC); or (3) a diet in which 37% of dietary DM was replaced with pellets of ground alfalfa (APSC). Rumen fluid, cecal digesta and feces were collected on d 5 of wk 4 of each period and the composition of the bacterial community was studied. Rumen fermentation responses were reported in a companion study. Both SARA-inducing challenges resulted in similar digesta pH depressions (as shown by the companion study), and reduced bacterial richness and diversity in rumen fluid, but GBSC had the larger effect. None of the challenges affected these measures in cecal digesta, and only GBSC reduced bacterial richness and diversity in feces. Only GBSC reduced the abundance of Bacteroidetes in rumen fluid. Abundances of limited number of bacterial genera identified by 16S rRNA gene sequencing in the rumen, cecum and feces were affected by the GBSC. The APSC did not affect any of these abundances. Both challenges increased the abundances of several starch, pectin, xylan, dextrin, lactate, succinate, and sugar fermenting bacterial species in the rumen, cecum, and feces as determined by qPCR. Only GBSC increased that of Megasphaera elsdenii in the rumen. Both challenges decreased the abundance of Streptococcus bovis, and increased that of Escherichia coli, in cecal digesta and feces, with GBSC having the larger effect. These results showed that

  6. Caractérisation géochimique des dykes basiques du massif de les Saras (Mayombe Congolais, Afrique Centrale): conséquences géodynamiquesGeochemical characterizations of basic dykes of the Saras massif (Congolese Mayombe Belt, Central Africa): geodynamic implications

    Science.gov (United States)

    Boni, J. Mpemba; Vellutini, P. J.

    1992-02-01

    The Saras granodioritic massif is one of the Eburnean intrusive plutons of the Mayombe Belt. (South-West Congo, Central Africa) It is crosscut by a system of basic dykes, of diversified composition. Petrographic data and a comparative geochemical study, using incompatible trace elements, shows a tholeiitic transitional affinity, and allow us to suggest that these dykes are continental basaltic suites, from extensive areas. This basic magmatism, scattered in the whole Congo Craton, marks a widespread extensional episode in relation with the formation of subsidence basins or true aulacogens, at about 970 Ma (Pan African).

  7. Towards quantitative simulations of high power proton cyclotrons

    Directory of Open Access Journals (Sweden)

    Y. J. Bi

    2011-05-01

    Full Text Available We describe a large scale simulation effort using Object Oriented Parallel Accelerator Library, that leads to a better quantitative understanding of the existing Paul Scherrer Institut high power proton cyclotron facility. The 1.3 MW of beam power on target poses stringent constraints on the controlled and uncontrolled beam losses. We present initial conditions for the Ring simulation, obtained from the new time-structure measurement and the many profile monitors of the 72 MeV transfer line. A trim coil model is developed, including trim coil TC15, which is needed to avoid the dangerous ν_{r}=2ν_{z} resonance. By properly selecting the injection position and angle (eccentric injection, the flattop voltage, and phase, very good agreement between simulations and measurements at the radial probe RRE4 is obtained. We report on 3–4 orders of magnitude in dynamic range when comparing simulations with measurements. The relation between beam intensity, rms beam size, and accelerating voltage is studied and compared with measurement. The demonstrated capabilities are mandatory in the design and operation of the next generation high power proton drivers. In an outlook we discuss our future plans to include more physics into the model, which eventually leads to an even larger dynamic range in the simulation.

  8. Electron-cyclotron plasma startup in the GDT experiment

    CERN Document Server

    Yakovlev, D V; Gospodchikov, E D; Solomakhin, A L; Savkin, V Ya; Bagryansky, P A

    2016-01-01

    The paper reports on a new plasma startup scenario in the Gas Dynamic Trap (GDT) magnetic mirror device. The primary 5 MW neutral beam injection (NBI) plasma heating system fires into a sufficiently dense plasma target ("seed plasma"), which is commonly supplied by an arc plasma generator. In the reported experiments, a different approach to seed plasma generation is explored. One of the channels of the electron cyclotron resonance (ECR) heating system is used to ionize the neutral gas and build up the density of plasma to a level suitable for NBI capture. After a short transition (about 1 ms) the discharge becomes essentially similar to a standard one initiated by the plasma gun. The paper presents the discharge scenario and experimental data on the seed plasma evolution during ECR heating, along with the dependencies on incident microwave power, magnetic configuration and pressure of a neutral gas. The characteristics of consequent high-power NBI discharge are studied and differences to the conventional sce...

  9. Simulating Electron Cyclotron Maser Emission for Low Mass Stars

    Science.gov (United States)

    Llama, Joe; Jardine, Moira

    2018-01-01

    Zeeman-Doppler Imaging (ZDI) is a powerful technique that enables us to map the large-scale magnetic fields of stars spanning the pre- and main-sequence. Coupling these magnetic maps with field extrapolation methods allow us to investigate the topology of the closed, X-ray bright corona, and the cooler, open stellar wind.Using ZDI maps of young M dwarfs with simultaneous radio light curves obtained from the VLA, we present the results of modeling the Electron-Cyclotron Maser (ECM) emission from these systems. We determine the X-ray luminosity and ECM emission that is produced using the ZDI maps and our field extrapolation model. We compare these findings with the observed radio light curves of these stars. This allows us to predict the relative phasing and amplitude of the stellar X-ray and radio light curves.This benchmarking of our model using these systems allows us to predict the ECM emission for all stars that have a ZDI map and an observed X-ray luminosity. Our model allows us to understand the origin of transient radio emission observations and is crucial for disentangling stellar and exoplanetary radio signals.

  10. Parallel Spectral Acquisition with an Ion Cyclotron Resonance Cell Array.

    Science.gov (United States)

    Park, Sung-Gun; Anderson, Gordon A; Navare, Arti T; Bruce, James E

    2016-01-19

    Mass measurement accuracy is a critical analytical figure-of-merit in most areas of mass spectrometry application. However, the time required for acquisition of high-resolution, high mass accuracy data limits many applications and is an aspect under continual pressure for development. Current efforts target implementation of higher electrostatic and magnetic fields because ion oscillatory frequencies increase linearly with field strength. As such, the time required for spectral acquisition of a given resolving power and mass accuracy decreases linearly with increasing fields. Mass spectrometer developments to include multiple high-resolution detectors that can be operated in parallel could further decrease the acquisition time by a factor of n, the number of detectors. Efforts described here resulted in development of an instrument with a set of Fourier transform ion cyclotron resonance (ICR) cells as detectors that constitute the first MS array capable of parallel high-resolution spectral acquisition. ICR cell array systems consisting of three or five cells were constructed with printed circuit boards and installed within a single superconducting magnet and vacuum system. Independent ion populations were injected and trapped within each cell in the array. Upon filling the array, all ions in all cells were simultaneously excited and ICR signals from each cell were independently amplified and recorded in parallel. Presented here are the initial results of successful parallel spectral acquisition, parallel mass spectrometry (MS) and MS/MS measurements, and parallel high-resolution acquisition with the MS array system.

  11. Development of helium electron cyclotron wall conditioning on TCV

    Science.gov (United States)

    Douai, D.; Goodman, T.; Isayama, A.; Fukumoto, M.; Wauters, T.; Sozzi, C.; Coda, S.; Blanchard, P.; Figini, L.; Garavaglia, S.; Miyata, Y.; Moro, A.; Ricci, D.; Silva, M.; Theiler, C.; Vartanian, S.; Verhaegh, K.; the EUROfusion MST1 Team; the TCV Team

    2018-02-01

    JT-60SA envisions electron cyclotron wall conditioning (ECWC), as wall conditioning method in the presence of the toroidal field to control fuel and impurity recycling and to improve plasma performance and reproducibility. This paper reports on Helium ECWC experiments on TCV in support of JT-60SA operation. Nearly sixty Helium conditioning discharges have been successfully produced in TCV, at a toroidal field B T  =  1.3 or 1.54 T, with gyrotrons at 82.7 GHz in X2 mode, mimicking ECWC operation in JT-60SA at the second harmonic of the EC wave. Discharge parameters were tuned in order to (i) minimize the time for the onset of ECWC plasmas, thus minimizing absorption of stray radiation by in-vessel components, (ii) improve discharge homogeneity by extending the discharge vertically and radially, and wall coverage, in particular of inboard surfaces where JT-60SA plasmas will be initiated, (iii) assess the efficiency of He-ECWC to deplete carbon walls from fuel. An optimized combination of vertical and radial magnetic fields, with amplitudes typically 0.1 to 0.6% of that of B T, has been determined, which resulted in lowest breakdown time, improved wall coverage and enhanced fuel removal. A standard ohmic D 2-plasma could be then sustained, whereas it would not have been possible without He-ECWC.

  12. High current DC negative ion source for cyclotron.

    Science.gov (United States)

    Etoh, H; Onai, M; Aoki, Y; Mitsubori, H; Arakawa, Y; Sakuraba, J; Kato, T; Mitsumoto, T; Hiasa, T; Yajima, S; Shibata, T; Hatayama, A; Okumura, Y

    2016-02-01

    A filament driven multi-cusp negative ion source has been developed for proton cyclotrons in medical applications. In Cs-free operation, continuous H(-) beam of 10 mA and D(-) beam of 3.3 mA were obtained stably at an arc-discharge power of 3 kW and 2.4 kW, respectively. In Cs-seeded operation, H(-) beam current reached 22 mA at a lower arc power of 2.6 kW with less co-extracted electron current. The optimum gas flow rate, which gives the highest H(-) current, was 15 sccm in the Cs-free operation, while it decreased to 4 sccm in the Cs-seeded operation. The relationship between H(-) production and the design/operating parameters has been also investigated by a numerical study with KEIO-MARC code, which gives a reasonable explanation to the experimental results of the H(-) current dependence on the arc power.

  13. Maryland University sectored isochronous cyclotron (MUSIC): Progress report No. 14

    Energy Technology Data Exchange (ETDEWEB)

    1967-01-10

    The past quarter has seen further progress in the solution of the problem of achieving a cyclotron which meets or exceeds the performance requirements. The magnet system, with the exception of the trim coils and their supplies, is all on order or about to be ordered, and a high confidence level exists that the system will meet all requirements. The rf system studies, nearly complete, have indicated that the solution chosen will meet the frequency requirements and will be within the power expected. The center studies, complete in the first phase, have resulted in a preliminary center design of the electrostatic focusing system and a design of the magnetic center which provides the required axial focusing. A high degree of cooperation on the center study programs between the U of M and CSF has efficiently yielded these results. The overall schedule continues to be maintained, and the program is expected to be completed on the 37-month schedule. For better control and greater visibility on schedule progress, two reference points have been selected as more immediate objectives. These are 17 July 1967 for the start of the magnet testing program and 2 October 1967 as the start of the rf high power tests. Each task involved is being analyzed with these dates in mind, and they appear to be reasonable.

  14. Characteristic Experimentations of Degrader and Scatterer at MC-50 Cyclotron

    CERN Document Server

    Lee Seok Ki; Kim, Kye-Ryung; Lee, Hwa-Ryun; Park, Bum-Sik

    2005-01-01

    Building proton beam user facilities, especially deciding beam energy level, depends on the attached proton accelerator and users' needs. To adjust beam energy level, two methods are generally used. One is to directly adjust the beam in the accelerator. The other is to adjust beam energy after extracting from the accelerator. Degrader/Scatterer System has been installed in the MC-50 Cyclotron to adjust energy level of the beam used for various application fields. Its degrader and scatterer are made of Al foils and Au foils, respectively. Al thickness are 2, 1, 0.5, 0.3, 0.2, 0.1, 0.05, 0.03, 0.02, 0.01mm and Au thickness are 0.2, 0.1, 0.05, 0.03, 0.02, 0.01mm, respectively. In this study, suitable beam condition was adjusted through overlapping Al/Au foils of various thickness through simulation results. After that, LET(Linear Energy Transfer) value was indirectly acquired by measuring the bragg peak of the external beam through PMMA plastic Phantom and profile was measured by film dosimetry.

  15. Isotope exchange by Ion Cyclotron Wall Conditioning on JET

    Energy Technology Data Exchange (ETDEWEB)

    Wauters, T., E-mail: t.wauters@fz-juelich.de [Laboratory for Plasma Physics, ERM/KMS, TEC Partner, 1000 Brussels (Belgium); Douai, D.; Kogut, D. [CEA, IRFM, F-13108 St-Paul-Lez-Durance (France); Lyssoivan, A. [Laboratory for Plasma Physics, ERM/KMS, TEC Partner, 1000 Brussels (Belgium); Brezinsek, S. [Forschungszentrum Jülich, Institut für Energie- und Klimaforschung Plasmaphysik, 52425 Jülich (Germany); Belonohy, E. [Max-Planck Institut für Plasmaphysik, 85748 Garching (Germany); Blackman, T. [JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Bobkov, V. [Max-Planck Institut für Plasmaphysik, 85748 Garching (Germany); Crombé, K. [Laboratory for Plasma Physics, ERM/KMS, TEC Partner, 1000 Brussels (Belgium); Drenik, A. [Jožef Stefan Institute, 1000 Ljubljana (Slovenia); Graham, M. [JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Joffrin, E. [CEA, IRFM, F-13108 St-Paul-Lez-Durance (France); Lerche, E. [Laboratory for Plasma Physics, ERM/KMS, TEC Partner, 1000 Brussels (Belgium); Loarer, T. [CEA, IRFM, F-13108 St-Paul-Lez-Durance (France); Lomas, P.L.; Mayoral, M.-L.; Monakhov, I. [JET-EFDA, Culham Science Centre, Abingdon OX14 3DB (United Kingdom); Oberkofler, M. [Max-Planck Institut für Plasmaphysik, 85748 Garching (Germany); Philipps, V. [Forschungszentrum Jülich, Institut für Energie- und Klimaforschung Plasmaphysik, 52425 Jülich (Germany); Plyusnin, V. [IST, Instituto de Plasmas e Fusão Nuclear, 1049-001 Lisboa (Portugal); and others

    2015-08-15

    The isotopic exchange efficiencies of JET Ion Cyclotron Wall Conditioning (ICWC) discharges produced at ITER half and full field conditions are compared for JET carbon (C) and ITER like wall (ILW). Besides an improved isotope exchange rate on the ILW providing cleaner plasma faster, the main advantage compared to C-wall is a reduction of the ratio of retained discharge gas to removed fuel. Complementing experimental data with discharge modeling shows that long pulses with high (∼240 kW coupled) ICRF power maximizes the wall isotope removal per ICWC pulse. In the pressure range 1–7.5 × 10{sup −3} Pa, this removal reduces with increasing discharge pressure. As most of the wall-released isotopes are evacuated by vacuum pumps in the post discharge phase, duty cycle optimization studies for ICWC on JET-ILW need further consideration. The accessible reservoir by H{sub 2}-ICWC at ITER half field conditions on the JET-ILW preloaded by D{sub 2} tokamak operation is estimated to be 7.3 × 10{sup 22} hydrogenic atoms, and may be exchanged within 400 s of cumulated ICWC discharge time.

  16. Electron cyclotron wave sources and applications for fusion

    Science.gov (United States)

    Thomassen, K. I.

    1990-03-01

    Advances in magnetic fusion research have come as often from the use of new technologies as from the invention of ideas and discovery of phenomena that are then applied to new experiments. The technologies needed for plasma production, heating, confinement, and control have largely been developed and are a major factor in the success of our current experiments. These include high vacuum techniques, normal and superconducting magnets, particle beams, pellet fueling devices, and rf sources in the ion cylotron and lower hybrid range of frequencies. One area where development is especially required, and where the potential impact on fusion research is large, is that of electron cyclotron wave (ECW) sources in the 100-600 GHz range. This journal issue is devoted to methods for ECW generation and transmission, and to applications including heating, current drive, profile shaping, and instability control. To help focus these articles the requirements(1) for a system to heat the Compact Ignition Tokamak (CIT) were used to define the necessary technology. Somewhat lower frequencies, but similar power, is anticipated(2) for the International Thermonuclear Experimental Reactor (ITER), and for future large devices of that class, should they use ECW sources in them.

  17. Applied research with cyclotron beams at FLNR JINR

    Energy Technology Data Exchange (ETDEWEB)

    Oganessian, Yu.Ts.; Apel, P.Yu.; Didyk, A.Yu.; Dmitriev, S.N.; Gulbekian, G.G. [Joint Inst. for Nuclear Research, Dubna, Moscow (Russian Federation). Flerov Lab. of Nuclear Reactions

    1997-03-01

    The Center of Applied Physics at the Flerov Laboratory carries out an R and D program comprising development of track membrane technology, materials research with heavy ion beams and production of radioisotopes. Experiments are performed on three cyclotrons: U-400, U-200 and IC-100 providing a wide variety of ion beams with the energies of 1 to 10 MeV/u. The activity on track membranes (TMs) includes studies of track formation in polymers and latent track structure, track sensitization and etching, methods of membrane testing, development of track membranes on the basis of new materials, surface modification of TMs, design and construction of facilities for track membrane production. Recent experiments on heavy ion-induced radiation damage in non-polymeric substances have been devoted to defect creation in semiconductor and dielectric single crystals. TEM, SEM, STM and `in situ` luminescent spectroscopy are used to investigate heavy ion effects. Methods for producing several isotopes of high radiochemical and isotopic purity for medical, biomedical and environmental protection applications have been developed. (author)

  18. Electron cyclotron plasma startup in the GDT experiment

    Science.gov (United States)

    Yakovlev, D. V.; Shalashov, A. G.; Gospodchikov, E. D.; Solomakhin, A. L.; Savkin, V. Ya.; Bagryansky, P. A.

    2017-01-01

    We report on a new plasma startup scenario in the gas dynamic trap (GDT) magnetic mirror device. The primary 5 MW neutral beam injection (NBI) plasma heating system fires into a sufficiently dense plasma target (‘seed plasma’), which is commonly supplied by an arc plasma generator. In the reported experiments, a different approach to seed plasma generation is explored. One of the channels of the electron cyclotron resonance (ECR) heating system is used to ionize the neutral gas and build up the density of plasma to a level suitable for NBI capture. After a short transition of approximately 1 ms the discharge becomes essentially similar to a standard one initiated by the plasma gun. This paper presents the discharge scenario and experimental data on the seed plasma evolution during ECRH, along with the dependencies on incident microwave power, magnetic configuration and pressure of a neutral gas. The characteristics of the consequent high-power NBI discharge are studied and differences from the conventional scenario are discussed. A theoretical model describing the ECR breakdown and the seed plasma accumulation in a large-scale mirror trap is developed on the basis of the GDT experiment.

  19. Electron cyclotron emission measurements at the stellarator TJ-K

    Energy Technology Data Exchange (ETDEWEB)

    Sichardt, Gabriel; Ramisch, Mirko [Institut fuer Grenzflaechenverfahrenstechnik und Plasmatechnologie, Universitaet Stuttgart (Germany); Koehn, Alf [Max-Planck-Institut fuer Plasmaphysik, Garching (Germany)

    2016-07-01

    Electron temperature (T{sub e}) measurements in the magnetised plasmas of the stellarator TJ-K are currently performed by means of Langmuir probes. The use of these probes is restricted to relatively low temperatures and the measurement of temperature profiles requires the acquisition of the local current-voltage characteristics which limits strongly the sampling rate. As an alternative, T{sub e} can be measured using the electron cyclotron emission (ECE) that is generated by the gyration of electrons in magnetised plasmas. Magnetic field gradients in the plasma lead to a spatial distribution of emission frequencies and thus the measured intensity at a given frequency can be related to its point of origin. The T{sub e} dependence of the intensity then leads to a temperature profile along the line of sight for Maxwellian velocity distributions. A diagnostic system for T{sub e} measurements using ECE is currently being set up at TJ-K. When non-thermal electrons are present the emission spectrum changes dramatically. Therefore, the ECE can also be used to investigate the contribution of fast electrons to previously observed toroidal net currents in TJ-K. Simulations are used to examine the role of electron drift orbits in generating these currents.

  20. On the origin of cyclotron lines in the spectra of X-ray pulsars

    Directory of Open Access Journals (Sweden)

    Mushtukov A. A.

    2014-01-01

    Full Text Available Cyclotron resonance scattering features are observed in the spectra of some X-ray pulsars and show significant changes in the line energy with the pulsar luminosity. In a case of bright sources, the line centroid energy is anti-correlated with the luminosity. Such a behaviour is often associated with the onset and growth of the accretion column, which is believed to be the origin of the observed emission and the cyclotron lines. However, this scenario inevitably implies large gradient of the magnetic field strength within the line-forming region, and it makes the formation of the observed line-like features problematic. Moreover, the observed variation of the cyclotron line energy is much smaller than could be anticipated for the corresponding luminosity changes. We argue that a more physically realistic situation is that the cyclotron line forms when the radiation emitted by the accretion column is reflected from the neutron star surface. The idea is based on the facts that a substantial part of column luminosity is intercepted by the neutron star surface and the reflected radiation should contain absorption features. The reflection model is developed and applied to explain the observed variations of the cyclotron line energy in a bright X-ray pulsar V 0332+53 over a wide range of luminosities.

  1. Support vector machine based fault detection approach for RFT-30 cyclotron

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Young Bae, E-mail: ybkong@kaeri.re.kr; Lee, Eun Je; Hur, Min Goo; Park, Jeong Hoon; Park, Yong Dae; Yang, Seung Dae

    2016-10-21

    An RFT-30 is a 30 MeV cyclotron used for radioisotope applications and radiopharmaceutical researches. The RFT-30 cyclotron is highly complex and includes many signals for control and monitoring of the system. It is quite difficult to detect and monitor the system failure in real time. Moreover, continuous monitoring of the system is hard and time-consuming work for human operators. In this paper, we propose a support vector machine (SVM) based fault detection approach for the RFT-30 cyclotron. The proposed approach performs SVM learning with training samples to construct the classification model. To compensate the system complexity due to the large-scale accelerator, we utilize the principal component analysis (PCA) for transformation of the original data. After training procedure, the proposed approach detects the system faults in real time. We analyzed the performance of the proposed approach utilizing the experimental data of the RFT-30 cyclotron. The performance results show that the proposed SVM approach can provide an efficient way to control the cyclotron system.

  2. mA beam acceleration efforts on 100 MeV H- cyclotron at CIAE

    Science.gov (United States)

    Zhang, Tianjue; An, Shizhong; Lv, Yinlong; Ge, Tao; Jia, Xianlu; Ji, Bin; Yin, Zhiguo; Pan, Gaofeng; Cao, Lei; Guan, Fengping; Yang, Jianjun; Li, Zhenguo; Zhao, Zhenlu; Wu, Longcheng; Zhang, He; Wang, Jingfeng; Zhang, Yiwang; Liu, Jingyuan; Li, Shiqiang; Lu, Xiaotong; Liu, Zhenwei; Li, Yaoqian; Guo, Juanjuan; Cao, Xuelong; Guan, Leilei; Wang, Fei; Wang, Yang; Yang, Guang; Zhang, Suping; Hou, Shigang; Wang, Feng

    2017-09-01

    Various technologies for high current compact H- cyclotron have been developed at CIAE since 1990s. A 375 μA proton beam was extracted from a 30 MeV compact H- cyclotron CYCIAE-30 at the end of 1994. A central region model cyclotron CYCIAE-CRM was developed for the design verification of a 100 MeV high current compact H- cyclotron CYCIAE-100. It is also a 10 MeV proton machine as a prototype for PET application. A 430 μA beam was achieved in 2009. The first beam was extracted from the CYCIAE-100 cyclotron on July 4, 2014, the operation stability has been improved and beam current has been increased gradually. A 1.1 mA proton beam was measured on the internal target in July 2016. The effort for an increasing of proton beam has continued till now. In this paper, the effort on several aspects for mA beam development will be presented, including the multi-cusp source, buncher, matching from the energy of the injected beam, vertical beam line and central region, beam loading of the RF system and instrumentation for beam diagnostics etc.

  3. Modeling whistler wave generation regimes in magnetospheric cyclotron maser

    Directory of Open Access Journals (Sweden)

    D. L. Pasmanik

    2004-11-01

    Full Text Available Numerical analysis of the model for cyclotron instability in the Earth's magnetosphere is performed. This model, based on the self-consistent set of equations of quasi-linear plasma theory, describes different regimes of wave generation and related energetic particle precipitation. As the source of free energy the injection of energetic electrons with transverse anisotropic distribution function to the interaction region is considered. A parametric study of the model is performed. The main attention is paid to the analysis of generation regimes for different characteristics of energetic electron source, such as the shape of pitch angle distributions and its intensity. Two mechanisms of removal of energetic electrons from a generation region are considered, one is due to the particle precipitation through the loss cone and another one is related to the magnetic drift of energetic particles.

    It was confirmed that two main regimes occur in this system in the presence of a constant particle source, in the case of precipitation losses. At small source intensity relaxation oscillations were found, whose parameters are in good agreement with simplified analytical theory developed earlier. At a larger source intensity, transition to a periodic generation occurs. In the case of drift losses the regime of self-sustained periodic generation regime is realized for source intensity higher than some threshold. The dependencies of repetition period and dynamic spectrum shape on the source parameters were studied in detail. In addition to simple periodic regimes, those with more complex spectral forms were found. In particular, alteration of spikes with different spectral shape can take place. It was also shown that quasi-stationary generation at the low-frequency band can coexist with periodic modulation at higher frequencies.

    On the basis of the results obtained, the model for explanation of

  4. Electron-cyclotron heating in the Constance 2 mirror experiment

    Energy Technology Data Exchange (ETDEWEB)

    Mauel, Michael E.

    1982-09-01

    Electron cyclotron heating of a highly-ionized plasma in mirror geometry is investigated. The experimental diagnosis of the electron energy distribution and the comparison of the results of this diagnosis with a two dimensional, time-dependent Fokker-Planck simulation are accomplished in four steps. (1) First, the power balance of the heated and unheated Constance 2 plasma is analyzed experimentally. It is concluded that the heated electrons escape the mirror at a rate dominated by a combination of the influx of cool electrons from outside the mirror and the increased loss rate of the ions. (2) The microwave parameters at the resonance zones are then calculated by cold-plasma ray tracing. High N/sub parallel/ waves are launched and for these waves, strong first-pass absorption is predicted. The absorption strength is qualitatively checked in the experiment by surrounding the plasma with non-reflecting liners. (3) A simplified quasilinear theory including the effect of N/sub parallel/ is developed to model the electrons. An analytic expression is derived for the RF-induced pump-out of the magnetically-confined warm electrons. Results of the Fokker-Planck simulations show the development of the electron energy distribution for several plasma conditions and verify the scaling of the analytic expression for RF-induced diffusion into the loss cone. (4) Sample x-ray and endloss data are presented, and the overall comparison between the simulation and experiment is discussed. The x-ray signals indicate that, for greater RF power, the hot electrondensity increases more rapidly than its temperature. The time history of the endloss data, illustrating RF-enhancement, suggests the predicted scaling for warm-electron pump-out. Finally, a comparison between the measured and predicted energy distribution shows that the bulk, warm and hot components of the heated Constance 2 electrons are indeed reproduced by the simulation.

  5. Electron cyclotron resonance heating in the microwave tokamak experiment

    Energy Technology Data Exchange (ETDEWEB)

    Allen, S.L.; Casper, T.A.; Fenstermacher, M.E. [and others

    1992-09-01

    This paper presents the results from a series of Electron Cyclotron Resonance Heating (ECRH) experiments on the Microwave Tokamak Experiment (MTX). On-axis heating at B{sub T} = 5T (f{sub ce} = 140 GHz) has been performed at electron densities up to cutoff. We have used both a long-pulse gryotron ({approximately}200 kW, {approximately}0.1s) and a pulsed Free Electron Laser (FEL) as microwave sources. Gyrotron experiments with power densities corresponding to 4 MW m{sup {minus}3}. A far infrared (FIR) polarimeter measured peaking of plasma current profiles in some discharges during the ECRH pulse. During high-power single-pulse FEL experiments, single-pass microwave !transmission measurements show nonlinear effects; i.e., higher transmission than predicted by linear theory. A corrugated-wall duct was used in the tokamak port to increase the gradient of the parallel refractive index n{sub parallel} of the incident wave, and increased absorption was observed. Evidence of electron tail heating during FEL pulses was observed on soft x-ray and ECE diagnostics. These results are in agreement with predictions of nonlinear theory; extrapolation of this theory to reactor-like conditions indicates efficient absorption and heating. A Laser Assisted Particle Probe Spectroscopy (LAPPS) diagnostic provided estimates of the vacuum electric field of the FEL which were consistent with the measured power. Multiple pulse operation of the ETA-II accelerator for the FEL has also been demonstrated, indicating the feasibility of high-average power FEL operation.

  6. The study of acceptance and the transmission efficiency of separated sector cyclotron

    Directory of Open Access Journals (Sweden)

    Li Xiaoni

    2015-01-01

    Full Text Available In this paper we present the study of the transversal and longitudinal acceptance and the transmission efficiency in the injection, acceleration, and extraction systems in the separated sector cyclotron of the heavy ion research facility in Lanzhou, China. The study of cyclotron acceptance is done for 238U36+ with energy of 97 MeV/u and for 70Zn10+ with energy of 5.62 MeV/u under the theoretical isochronous and real magnetic field distribution. From the simulation results it can be seen that the transmission efficiency and the acceptances of separated sector cyclotron can be improved by redesign the curvature of MSI3 deflector or by introducing the magnet shim in MSI3 deflector region to change the distribution of the inner magnetic field. [Projekat Ministarstva nauke Republike Srbije, br. OI-171018

  7. Results from the Project 8 phase-1 cyclotron radiation emission spectroscopy detector

    Science.gov (United States)

    Ashtari Esfahani, A.; Böser, S.; Claessens, C.; de Viveiros, L.; Doe, P. J.; Doeleman, S.; Fertl, M.; Finn, E. C.; Formaggio, J. A.; Guigue, M.; Heeger, K. M.; Jones, A. M.; Kazkaz, K.; LaRoque, B. H.; Machado, E.; Monreal, B.; Nikkel, J. A.; Oblath, N. S.; Robertson, R. G. H.; Rosenberg, L. J.; Rybka, G.; Saldaña, L.; Slocum, P. L.; Tedeschi, J. R.; Thümmler, T.; Vandevender, B. A.; Wachtendonk, M.; Weintroub, J.; Young, A.; Zayas, E.

    2017-09-01

    The Project 8 collaboration seeks to measure the absolute neutrino mass scale by means of precision spectroscopy of the beta decay of tritium. Our technique, cyclotron radiation emission spectroscopy, measures the frequency of the radiation emitted by electrons produced by decays in an ambient magnetic field. Because the cyclotron frequency is inversely proportional to the electron’s Lorentz factor, this is also a measurement of the electron’s energy. In order to demonstrate the viability of this technique, we have assembled and successfully operated a prototype system, which uses a rectangular waveguide to collect the cyclotron radiation from internal conversion electrons emitted from a gaseous 83m Kr source. Here we present the main design aspects of the first phase prototype, which was operated during parts of 2014 and 2015. We will also discuss the procedures used to analyze these data, along with the features which have been observed and the performance achieved to date.

  8. Optimized feed-forward neural-network algorithm trained for cyclotron-cavity modeling

    Science.gov (United States)

    Mohamadian, Masoumeh; Afarideh, Hossein; Ghergherehchi, Mitra

    2017-01-01

    The cyclotron cavity presented in this paper is modeled by a feed-forward neural network trained by the authors’ optimized back-propagation (BP) algorithm. The training samples were obtained from simulation results that are for a number of defined situations and parameters and were achieved parametrically using MWS CST software; furthermore, the conventional BP algorithm with different hidden-neuron numbers, structures, and other optimal parameters such as learning rate that are applied for our purpose was also used here. The present study shows that an optimized FFN can be used to estimate the cyclotron-model parameters with an acceptable error function. A neural network trained by an optimized algorithm therefore shows a proper approximation and an acceptable ability regarding the modeling of the proposed structure. The cyclotron-cavity parameter-modeling results demonstrate that an FNN that is trained by the optimized algorithm could be a suitable method for the estimation of the design parameters in this case.

  9. Absorption and emission of extraordinary-mode electromagnetic waves near cyclotron frequency in nonequilibrium plasmas

    Science.gov (United States)

    Wu, C. S.; Lin, C. S.; Wong, H. K.; Tsai, S. T.; Zhou, R. L.

    1981-01-01

    An investigation is presented of two cases: (1) weakly relativistic electrons with a loss-cone type distribution, and (2) electrons with a drift velocity parallel to the ambient magnetic field. Numerical computations are given for physical parameters close to those in the polar region of the earth magnetosphere and laboratory experiments, with attention to the fast extraordinary-mode radiation whose frequency is near that of the electron cyclotron frequency. The fast extraordinary mode can escape from a strong field region to the weaker field region and may therefore be measured outside the plasma. It is found that the X mode radiation can be amplified by means of a cyclotron maser effect when the electrons have a loss-cone distribution, and it is concluded that, when the electron energy is sufficiently high, the X mode cutoff frequency may be lower than the cyclotron frequency.

  10. Differentiating Fragmentation Pathways of Cholesterol by Two-Dimensional Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.

    Science.gov (United States)

    van Agthoven, Maria A; Barrow, Mark P; Chiron, Lionel; Coutouly, Marie-Aude; Kilgour, David; Wootton, Christopher A; Wei, Juan; Soulby, Andrew; Delsuc, Marc-André; Rolando, Christian; O'Connor, Peter B

    2015-12-01

    Two-dimensional Fourier transform ion cyclotron resonance mass spectrometry is a data-independent analytical method that records the fragmentation patterns of all the compounds in a sample. This study shows the implementation of atmospheric pressure photoionization with two-dimensional (2D) Fourier transform ion cyclotron resonance mass spectrometry. In the resulting 2D mass spectrum, the fragmentation patterns of the radical and protonated species from cholesterol are differentiated. This study shows the use of fragment ion lines, precursor ion lines, and neutral loss lines in the 2D mass spectrum to determine fragmentation mechanisms of known compounds and to gain information on unknown ion species in the spectrum. In concert with high resolution mass spectrometry, 2D Fourier transform ion cyclotron resonance mass spectrometry can be a useful tool for the structural analysis of small molecules. Graphical Abstract ᅟ.

  11. Magnetic field calculation for a 13 MeV PET cyclotron

    CERN Document Server

    Yang, W Y; Oh, S; Chai, J S; Ha, J H

    1999-01-01

    A design study of the main magnet for a 13 MeV cyclotron has been carried out in a joint collaboration between the Korea Cancer Center Hospital (KCCH) and POSTECH. A maximum energy of 13 MeV has been chosen to produce radioisotopes such as /sup 18/F. There are four magnet sectors, each with radial-ridged shape. Maximum magnetic fields are 1.85 T and 0.48 T at hill and valley centers, respectively. The total size of the cyclotron is less than 2 m in diameter. The program TOSCA has been utilized for the field calculation and optimization. In this paper, we describe design parameters of the 13 MeV PET cyclotron, with emphasis on the magnetic field shape and the beam optics calculation. (3 refs).

  12. Experiments on ion cyclotron damping at the deuterium fourth harmonic in DIII-D

    Energy Technology Data Exchange (ETDEWEB)

    Pinsker, R. I. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Baity, F. W. [Oak Ridge National Laboratory, Oak Ridge, Tennessee (United States); Bernabei, S. [Princeton Plasma Physics Laboratory, Princeton, New Jersey (United States); Greenough, N. [Princeton Plasma Physics Laboratory, Princeton, New Jersey (United States); Heidbrink, W. W. [University of California, Irvine, California (United States); Mau, T. K. [University of California, San Diego, California (United States); Petty, C. C. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Porkolab, M. [Massachusetts Institute of Technology, Cambridge, Massachusetts (United States)

    1999-09-20

    Absorption of fast Alfven waves by the energetic ions of an injected beam is evaluated in the DIII-D tokamak. Ion cyclotron resonance absorption at the fourth harmonic of the deuteron cyclotron frequency is observed with deuterium neutral beam injection (f=60 MHz, B{sub T}=1.9 T). Enhanced D-D neutron rates are evidence of absorption at the Doppler-shifted cyclotron resonance. Characteristics of global energy confinement provide further proof of substantial beam acceleration by the rf. In many cases, the accelerated deuterons cause temporary stabilization of the sawtooth (''monster sawteeth''), at relatively low rf power levels of {approx}1 MW. (c) 1999 American Institute of Physics.

  13. Topological model of composite fermions in the cyclotron band generator picture: New insights

    Science.gov (United States)

    Staśkiewicz, Beata

    2018-03-01

    A combinatorial group theory in the braid groups is correlated with the unusual "anyon" statistic of particles in 2D Hall system in the fractional quantum regime well. On this background has been derived cyclotron band generator as a modification and generalization band generator, first established to solve the word and conjugacy problems in the braid group terms. Topological commensurability condition has been embraced by canonical factors - like, based on the concept of parallel descending cycles. Owing to this we can mathematically capture the general hierarchy of correlated states in the lowest Landau level, describing the fractional quantum Hall effect hierarchy, in terms of cyclotron band generators, especially for those being beyond conventional composite fermions model. It has been also shown that cyclotron braid subgroups, developed for interpretation of Laughlin correlations, are a special case of the right-angled Artin groups.

  14. Improving cancer treatment with cyclotron produced radionuclides. Comprehensive progress report, February 1, 1990--January 31, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Larson, S.M. Finn, R.D.

    1992-08-04

    This report describes the author`s continuing long term goal of promoting nuclear medicine applications by improving the scientific basis for tumor diagnosis treatment and treatment follow-up based on the use of cyclotron produced radiotracers in oncology. The program has 3 interactive components: Radiochemistry /Cyclotron; Pharmacology; and Immunology. An essential strategy is as follows: novel radionuclides and radiotracers developed in the Radiochemistry/Cyclotron section under the DOE grant during the 1989--1992 grant period, will be employed in the Pharmacology and Immunology sections of the DOE grant during the 1992--1995 grant period. The development of novel radionuclides and tracers is of course useful in and of itself, but their utility is greatly enhanced by the interaction with the immunology and pharmacology components of the program.

  15. A cyclotron isotope production facility designed to maximize production and minimize radiation dose

    Science.gov (United States)

    Dickie, W. J.; Stevenson, N. R.; Szlavik, F. F.

    1993-06-01

    Continuing increases in requirements from the nuclear medicine industry for cyclotron isotopes is increasing the demands being put on an aging stock of machines. In addition, with the 1990 recommendations of the ICRP publication in place, strict dose limits will be required and this will have an effect on the way these machines are being operated. Recent advances in cyclotron design combined with lessons learned from two decades of commercial production mean that new facilities can result in a substantial charge on target, low personnel dose, and minimal residual activation. An optimal facility would utilize a well engineered variable energy/high current H - cyclotron design, multiple beam extraction, and individual target caves. Materials would be selected to minimize activation and absorb neutrons. Equipment would be designed to minimize maintenance activities performed in high radiation fields.

  16. Comment on the determination of Fermi-liquid parameters from cyclotron-wave measurements using empirical procedures

    DEFF Research Database (Denmark)

    Gordon, R A; Frandsen, J.B.

    1978-01-01

    The application of empirical procedures is shown to lead to a number of ambiguities or errors in the determination of cyclotron-wave dispersion curves. As a result of such ambiguities or errors, it is pointed out that the presently quoted values of the Fermi-liquid parameters {Ai}, i≥2, obtained...... from cyclotron-wave dispersion curves, can not be considered reliable....

  17. [Decommissioning of the medical cyclotron in National Center of Neurology and Psychiatry].

    Science.gov (United States)

    Ito, Kimiteru; Nakata, Yasuhiro; Matsuda, Hiroshi; Sato, Noriko

    2011-05-01

    In Japan, positron emission tomography has prevailed as a useful procedure for detecting malignancy, myocardial viability, and epileptic foci. Consequently, compact medical cyclotrons have been installed in many hospitals. However, reports about the dismantling or decommissioning of compact medical cyclotrons are rare. This report describes the series of steps involved in the decommissioning of a compact medical cyclotron that had been used to produce radioactively tagged substances over a period of fifteen years at the National Center of Neurology and Psychiatry in Japan. Additionally, this report describes the manner in which the radioactive waste was disposed. The plan to decommission the cyclotron was comprised of three phases: a preliminary survey, the dismantling work, and a reports after the dismantling. We complied with the guidelines for the disposal of radioactive waste published by the Ministry of Education, Culture, Sports, Science and Technology. The most radioactive material was the vacuuming foil used in the window of the target chamber, with a dose rate of 17 microSv/h (gamma rays) and 20 x 10(3) cpm (beta rays). The detected radionuclides were mainly 22Na, 57Co, 60Co and 65Zn. The total numbers of radioactive waste containers were thirteen 200 l containers and one 50 l container. We suspect that the long shutdown period of the cyclotron (more than one year) contributed to the decay of the radioactive waste because the amount of containers was smaller than the initial estimation. The shutdown period of a cyclotron may play a significant role in reducing the amount of radioactive waste.

  18. Biomedical research with cyclotron produced radionuclides. Progress report, October 1, 1977--September 30, 1978

    Energy Technology Data Exchange (ETDEWEB)

    Laughlin, J.S.; Benua, R.S.; Tilbury, R.S.; Bigler, R.E.

    1978-09-30

    Progress is reported on biomedical studies using cyclotron-produced /sup 18/F, /sup 15/O, /sup 11/C, /sup 13/N, /sup 52/Fe, /sup 38/K, /sup 206/Bi, /sup 73/Se, /sup 53/Co, and /sup 43/K. The following research projects are described: tumor detection and diagnosis; neurological studies; radiopharmaceutical development; /sup 38/K as an indicator of blood flow to the myocardium; dosimetry for internally deposited isotopes in animals and man; cyclotron development; positron tomographic imaging with the TOKIM System; and review of positron emission transaxial tomograph instruments. (HLW)

  19. First results of electron cyclotron emission measurements at the GDT magnetic mirror

    CERN Document Server

    Shalashov, A G; Gospodchikov, E D; Lubyako, L V; Yakovlev, D V; Bagryansky, P A

    2016-01-01

    This paper summarizes the results of experiments on electron cyclotron emission (ECE) measurements at the fundamental harmonic recently performed at the axially symmetric magnetic mirror device GDT (Budker Institute, Novosibirsk). New ECE diagnostics is installed to facilitate the successful electron cyclotron resonance heating experiment and operates in the vicinity of the heating frequency of 54.5 GHz. Besides expected emission of thermal electrons, a clearly resolved non-thermal ECE is observed indicating the presence of suprathermal electrons driven by high-power microwave heating. The particulars of plasma emission are studied experimentally in a broad range of discharge scenarios.

  20. Neutron transport calculation for Activation Evaluation for Decommissioning of PET cyclotron Facility

    Science.gov (United States)

    Nobuhara, Fumiyoshi; Kuroyanagi, Makoto; Masumoto, Kazuyoshi; Nakamura, Hajime; Toyoda, Akihiro; Takahashi, Katsuhiko

    2017-09-01

    In order to evaluate the state of activation in a cyclotron facility used for the radioisotope production of PET diagnostics, we measured the neutron flux by using gold foils and TLDs. Then, the spatial distribution of neutrons and induced activity inside the cyclotron vault were simulated with the Monte Calro calculation code for neutron transport and DCHAIN-SP for activation calculation. The calculated results are in good agreement with measured values within factor 3. Therefore, the adaption of the advanced evaluation procedure for activation level is proved to be important for the planning of decommissioning of these facilities.

  1. Cyclotron resonance in InAs/GaSb heterostructure in inclined magnetic field

    CERN Document Server

    Greshnov, A A; Vasilev, Yu B; Suchalkin, S D; Meltser, B Y; Ivanov, S V; Kopev, P S

    2002-01-01

    The mechanism of splitting the cyclotron resonance line in the InAs/GaSb heterostructure in the inclined magnetic field is experimentally and theoretically studied. It is shown that the electrons and holes mixing in leads to the anticrossing Landau levels and consequently to the cyclotron resonance line splitting. Splitting in the case of the inclined magnetic field was not observed which is explained by damping the electrons and holes states mixing in on the account of originating the additional barrier for the electrons and holes by availability of the magnetic field longitudinal constituent

  2. The 88-Inch Cyclotron: A One-Stop Facility for Electronics Radiation and Detector Testing

    Energy Technology Data Exchange (ETDEWEB)

    Kireeff Covo, M.; Albright, R. A.; Ninemire, B. F.; Johnson, M. B.; Hodgkinson, A.; Loew, T.; Benitez, J. Y.; Todd, D. S.; Xie, D. Z.; Perry, T.; Phair, L.; Bernsteiny, L. A.; Bevins, J.; Brown, J. A.; Goldblum, B. L.; Harasty, M.; Harrig, K. P.; Laplace, T. A.; Matthews, E. F.; Bushmaker, A.; Walker, D.; Oklejas, V.; Hopkins, A. R.; Bleuel, D. L.; Chen, J.; Cronin, S. B.

    2017-10-01

    In outer space down to the altitudes routinely flown by larger aircrafts, radiation can pose serious issues for microelectronics circuits. The 88-Inch Cyclotron at Lawrence Berkeley National Laboratory is a sector-focused cyclotron and home of the Berkeley Accelerator Space Effects Facility, where the effects of energetic particles on sensitive microelectronics are studied with the goal of designing electronic systems for the space community. This paper describes the flexibility of the facility and its capabilities for testing the bombardment of electronics by heavy ions, light ions, and neutrons. Experimental capabilities for the generation of neutron beams from deuteron breakups and radiation testing of carbon nanotube field effect transistor will be discussed.

  3. Solid targets for production of radioisotopes with cyclotron; Blancos solidos para produccion de radioisotopos con ciclotron

    Energy Technology Data Exchange (ETDEWEB)

    Paredes G, L.; Balcazar G, M. [Instituto Nacional de Investigaciones Nucleares, Direccion de Investigacion Tecnologica, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    1999-07-01

    The design of targets for production of radioisotopes and radiopharmaceuticals of cyclotron to medical applications requires a detailed analysis of several variables such as: cyclotron operation conditions, choice of used materials as target and their physicochemical characteristics, activity calculation, the yielding of each radioisotope by irradiation, the competition of nuclear reactions in function of the projectiles energy and the collision processes amongst others. The objective of this work is to determine the equations for the calculation for yielding of solid targets at the end of the proton irradiation. (Author)

  4. Unidirectional stripping extraction from a cyclotron which accelerates light as well as heavy ions

    Directory of Open Access Journals (Sweden)

    Jasna L. Ristić-Djurović

    2003-03-01

    Full Text Available The VINCY Cyclotron (VINča CYclotron is a multipurpose machine intended to accelerate light as well as heavy ions. To extract heavy ions with low energy and light ions an extraction system with stripping foil is used. Heavy ions with high energy will be extracted by means of an electrostatic deflector. The former extraction system will be manufactured and used first. The proposed unidirectional stripping extraction system is the optimal balance between the placement of the extraction line and the required diversity and quality of the extracted beam. The available range of extraction directions is set by geometry limitations.

  5. A simple thick target for production of 89Zr using an 11 MeV cyclotron

    Science.gov (United States)

    Link, Jeanne M.; Krohn, Kenneth A.; O’Hara, Matthew J.

    2017-01-01

    The growing interest but limited availability of 89Zr for PET led us to test targets for the 89Y(p,n) reaction. The goal was an easily constructed target for an 11 MeV Siemens cyclotron. Yttrium foils were tested at different thicknesses, angles and currents. A 90° foil tolerated 41 μA without damage and produced ~800 MBq/h, > 20 mCi, an amount adequate for radiochemistry research and human doses in a widely available accelerator. This method should translate to higher energy cyclotrons. PMID:28187357

  6. The electrostatic ion-cyclotron instability-a two-dimensional potential relaxation instability

    DEFF Research Database (Denmark)

    Popa, G.; Schrittwieser, R.; Juul Rasmussen, Jens

    1985-01-01

    An experimental investigation shows that the electrostatic ion-cyclotron instability, driven by an electron current to a positively biased collector, is accompanied by strong coherent two-dimensional fluctuations of the plasma potential in front of the collector. These results suggest that this i......An experimental investigation shows that the electrostatic ion-cyclotron instability, driven by an electron current to a positively biased collector, is accompanied by strong coherent two-dimensional fluctuations of the plasma potential in front of the collector. These results suggest...

  7. The influence of the edge density fluctuations on electron cyclotron wave beam propagation in tokamaks

    DEFF Research Database (Denmark)

    Bertelli, N.; Balakin, A.A.; Westerhof, E.

    2010-01-01

    A numerical analysis of the electron cyclotron (EC) wave beam propagation in the presence of edge density fluctuations by means of a quasi-optical code [Balakin A. A. et al, Nucl. Fusion 48 (2008) 065003] is presented. The effects of the density fluctuations on the wave beam propagation are estim......A numerical analysis of the electron cyclotron (EC) wave beam propagation in the presence of edge density fluctuations by means of a quasi-optical code [Balakin A. A. et al, Nucl. Fusion 48 (2008) 065003] is presented. The effects of the density fluctuations on the wave beam propagation...

  8. Medium to large scale radioisotope production for targeted radiotherapy using a small PET cyclotron

    DEFF Research Database (Denmark)

    Thisgaard, Helge; Jensen, Mikael; Elema, Dennis Ringkjøbing

    2011-01-01

    In recent years the use of radionuclides in targeted cancer therapy has increased. In this study we have developed a high-current solid target system and demonstrated that by the use of a typical low-energy medical cyclotron, it is possible to produce tens of GBq's of many unconventional radionuc......In recent years the use of radionuclides in targeted cancer therapy has increased. In this study we have developed a high-current solid target system and demonstrated that by the use of a typical low-energy medical cyclotron, it is possible to produce tens of GBq's of many unconventional...

  9. ROKCY-12 (KCCH PET-dedicated cyclotron): main features and improvements

    Energy Technology Data Exchange (ETDEWEB)

    Chai, J. S.; Kim, Y. S.; Yang, Y. T.; Jung, I. S.; Hong, S. S.; Lee, M. Y.; Jang, H. S.; Kim, J. H. [Korea Cancer Center Hospital, Seoul (Korea, Republic of)

    2002-07-01

    In this paper, we describe the development of 13 MeV cyclotron (ROKCY-12) that can be used for a Position Emission Tomography(PET) purpose. This cyclotron with a maximum beam energy of 13 MeV can produce radio isotopes especially {sup 18}F which has a relatively short half lifetime of 110 minutes. First, we show the beam characteristics can be used to carry out the operation of ROCKY-12. Based on this, a computer program has been developed to determine main cyclotron parameters such as cyclotron magnet, RF system, ion source, vacuum system and other cyclotron operation parameters. And then we show the result of design and manufacturing feature of ROKCY-12. By using this design program, one can determines magnet yoke geometry and the average magnetic fields etc. And then the three-dimensional computer program OPERA-3D has been invoked to determine magnet pole tips. Validity of the design can be seen by investigating magnetic fields, radial and vertical focusing frequencies as a function of the beam energy. In this paper, we show the results of cyclotron beam by ROCKY-12. We designed 77.3 MHz RF system and ion source system. We tested RF resonance each coupling methods. We show the result of RF design and prototype operation. Developed ion source is PIG type. We described our design methods and implementation. We report the result of getting negative hydrogen ion. Cyclotron controller asks inputs of every sensor and output of every instrument for notifying current condition to operator. It has independent controllers, for example DC power supply, vacuum system, beam profile system, beam extraction system, RF system, ion source, cooling unit and so on. Basically, each control system uses RS-485 for communication to main control computer. Consumers reward products and services that feature quality, originality, a distinct personality and charm. The International Standardization Organization (ISO) requires, as its mission, that we achieve competitive superiority by

  10. Neutron transport calculation for Activation Evaluation for Decommissioning of PET cyclotron Facility

    Directory of Open Access Journals (Sweden)

    Nobuhara Fumiyoshi

    2017-01-01

    Full Text Available In order to evaluate the state of activation in a cyclotron facility used for the radioisotope production of PET diagnostics, we measured the neutron flux by using gold foils and TLDs. Then, the spatial distribution of neutrons and induced activity inside the cyclotron vault were simulated with the Monte Calro calculation code for neutron transport and DCHAIN-SP for activation calculation. The calculated results are in good agreement with measured values within factor 3. Therefore, the adaption of the advanced evaluation procedure for activation level is proved to be important for the planning of decommissioning of these facilities.

  11. Purification of cyclotron-produced {sup 203}Pb for labeling Herceptin

    Energy Technology Data Exchange (ETDEWEB)

    Garmestani, Kayhan [Radioimmune and Inorganic Chemistry Section, Radiation Oncology Branch, NCI, Bethesda, MD 20892-1002 (United States); Milenic, Diane E. [Radioimmune and Inorganic Chemistry Section, Radiation Oncology Branch, NCI, Bethesda, MD 20892-1002 (United States); Brady, Erik D. [Radioimmune and Inorganic Chemistry Section, Radiation Oncology Branch, NCI, Bethesda, MD 20892-1002 (United States); Plascjak, Paul S. [PET Department, Clinical Center, NIH, Bethesda, MD 20892-1002 (United States); Brechbiel, Martin W. [Radioimmune and Inorganic Chemistry Section, Radiation Oncology Branch, NCI, Bethesda, MD 20892-1002 (United States)]. E-mail: martinwb@mail.nih.gov

    2005-04-01

    A simple and rapid procedure was developed for the purification of cyclotron-produced {sup 203}Pb via the {sup 203}Tl(d,2n) {sup 203}Pb reaction. A Pb(II) selective ion-exchange resin, with commercial name Pb Resin from Eichrom Technologies, Inc., was used to purify {sup 203}Pb from the cyclotron-irradiated Tl target with excellent recovery of the enriched Tl target material. The purified {sup 203}Pb was used to radiolabel the monoclonal antibody Herceptin. The in vitro and in vivo properties of the {sup 203}Pb radioimmunoconjugate were evaluated.

  12. Development of an 18 GHz superconducting electron cyclotron resonance ion source at RCNP.

    Science.gov (United States)

    Yorita, Tetsuhiko; Hatanaka, Kichiji; Fukuda, Mitsuhiro; Kibayashi, Mitsuru; Morinobu, Shunpei; Okamura, Hiroyuki; Tamii, Atsushi

    2008-02-01

    An 18 GHz superconducting electron cyclotron resonance ion source has recently been developed and installed in order to extend the variety and the intensity of ions at the RCNP coupled cyclotron facility. Production of several ions such as O, N, Ar, Kr, etc., is now under development and some of them have already been used for user experiments. For example, highly charged heavy ion beams like (86)Kr(21+,23+) and intense (16)O(5+,6+) and (15)N(6+) ion beams have been provided for experiments. The metal ion from volatile compounds method for boron ions has been developed as well.

  13. Effects of energetic heavy ions on electromagnetic ion cyclotron wave generation in the plasmapause region

    Science.gov (United States)

    Kozyra, J. U.; Cravens, T. E.; Nagy, A. F.; Fontheim, E. G.; Ong, R. S. B.

    1984-01-01

    An expression for electromagnetic ion cyclotron convective growth rates is derived. The derivation of the dispersion relation and convective growth rates in the presence of a multicomponent energetic and cold plasma is presented. The effects that multiple heavy ions in the ring current and cold plasma produce in the growth and propagation characteristics of ion cyclotron waves are explored. Results of growth rate calculations using parameters consistent with conditions in the plasmapause region during the early recovery phase of geomagnetic storms are presented and compared with ground-based and satellite observations of waves in this region. The geophysical implications of the results are discussed.

  14. New Cyclotron Targetry to Enhance F-18 clinical Position Emission Tomography

    Energy Technology Data Exchange (ETDEWEB)

    J. Michael Doster

    2008-12-19

    This project proposes to develop cyclotron targets that produce F-18 for clinical Positron Emission Tomography (PET) at significantly higher rates than that available from current targetry. This production rate of 18F is directly proportional to the beam current. Higher beam currents would result in increased 18F production but would be accompanied by higher heat loads to the target. The beam power available in most commercial cyclotrons exceeds the heat removal capacity of current target technology by a factor of two to four, significantly limiting the production rate of Fluorine-18.

  15. Electron cyclotron emission at the fundamental harmonic in GDT magnetic mirror

    Science.gov (United States)

    Shalashov, A. G.; Solomakhin, A. L.; Gospodchikov, E. D.; Lubyako, L. V.; Yakovlev, D. V.; Bagryansky, P. A.

    2017-08-01

    New electron cyclotron emission (ECE) diagnostics has been installed to facilitate the successful experiment of electron cyclotron plasma heating (ECRH) in a large open magnetic trap GDT at Budker Institute. The particularities of ECE in the vicinity of the ECRH frequency were studied experimentally for a broad range of discharge scenarios. The measured thermal emission has partly validated the existing physical conceptions about microwave plasma heating in the machine. Besides the expected emission of thermal electrons, a clearly resolved non-thermal ECE was observed which unambiguously confirmed the presence of suprathermal electrons driven by high-power microwave heating.

  16. Status report of the multipurpose superconducting electron cyclotron resonance ion source

    NARCIS (Netherlands)

    Ciavola, G.; Gammino, S.; Barbarino, S.; Celona, L.; Consoli, F.; Gallo, G.; Maimone, F.; Mascali, D.; Passarello, S.; Galata, A.; Tinschert, K.; Spaedtke, P.; Lang, R.; Maeder, J.; Rossbach, J.; Koivisto, H.; Savonen, M.; Koponen, T.; Suominen, P.; Ropponen, T.; Barue, C.; Lechartier, M.; Beijers, J. P. M.; Brandenburg, S.; Kremers, H. R.; Vanrooyen, D.; Kuchler, D.; Scrivens, R.; Schachter, L.; Dobrescu, S.; Stiebing, K.

    Intense heavy ion beam production with electron cyclotron resonance (ECR) ion sources is a common requirement for many of the accelerators under construction in Europe and elsewhere. An average increase of about one order of magnitude per decade in the performance of ECR ion sources was obtained up

  17. LIBO - boosting medical cyclotron facilities for cancer therapy Exhibition LEPFest 2000

    CERN Multimedia

    2000-01-01

    Length : Energy boost : From 62 to 200 MeVAccelerating gradient : 10 MeV/metreAccelerating frequency : 3 GHz Collaboration : CERN, INFN and University of Milan, INFN and University of Naples and TERA foundation Prototype test in 2001 : SC cyclotron Catania

  18. Modelling third harmonic ion cyclotron acceleration of deuterium beams for JET fusion product studies experiments

    DEFF Research Database (Denmark)

    Schneider, M.; Johnson, T.; Dumont, R.

    2016-01-01

    Recent JET experiments have been dedicated to the studies of fusion reactions between deuterium (D) and Helium-3 (3He) ions using neutral beam injection (NBI) in synergy with third harmonic ion cyclotron radio-frequency heating (ICRH) of the beam. This scenario generates a fast ion deuterium tail...

  19. Analysis of Chaperone Complexes by Fourier Transform Ion Cyclotron Resonance Mass Spectrometry

    NARCIS (Netherlands)

    Geels, R.B.J.

    2008-01-01

    Investigation of methodologies for analyses of noncovalently bound protein assemblies using Fourier transformation ion cyclotron resonance mass spectrometry (FT-ICR-MS) and quadrupole Time-of-Flight (qToF) mass spectrometry. Specifically, the co-chaperonins GroEL and gp31 are used to perform

  20. Study of the Polarization Strategy for Electron Cyclotron Heating Systems on HL-2M

    Science.gov (United States)

    Zhang, F.; Huang, M.; Xia, D. H.; Song, S. D.; Wang, J. Q.; Huang, B.; Wang, H.

    2016-06-01

    As important components integrated in transmission lines of electron cyclotron heating systems, polarizers are mainly used to obtain the desired polarization for highly efficient coupling between electron cyclotron waves and plasma. The polarization strategy for 105-GHz electron cyclotron heating systems of HL-2M tokamak is studied in this paper. Considering the polarizers need high efficiency, stability, and low loss to realize any polarization states, two sinusoidal-grooved polarizers, which include a linear polarizer and an elliptical polarizer, are designed with the coordinate transformation method. The parameters, the period p and the depth d, of two sinusoidal-grooved polarizers are optimized by a phase difference analysis method to achieve an almost arbitrary polarization. Finally, the optimized polarizers are manufactured and their polarization characteristics are tested with a low-power test platform. The experimental results agree well with the numerical calculations, indicating that the designed polarizers can meet the polarization requirements of the electron cyclotron heating systems of HL-2M tokamak.

  1. Destabilization of fast particle stabilized sawteeth in ASDEX Upgrade with electron cyclotron current drive

    DEFF Research Database (Denmark)

    Igochine, V.; Chapman, I.T.; Bobkov, V.

    2011-01-01

    Upgrade for destabilization of fast particle stabilized sawteeth with electron cyclotron current drive (ECCD). It is shown that moderate ECCD from a single gyrotron is able to destabilize the fast particle stabilized sawteeth. A reduction in sawtooth period by about 40% was achieved in first experiments...

  2. The smooth cyclotron line in Her X-1 as seen with NuSTAR

    DEFF Research Database (Denmark)

    Fuerst, Felix; Grefenstette, Brian W.; Staubert, Ruediger

    2013-01-01

    Her X-1, one of the brightest and best studied X-ray binaries, shows a cyclotron resonant scattering feature (CRSF) near 37 keV. This makes it an ideal target for detailed study with the Nuclear Spectroscopic Telescope Array (NuSTAR), taking advantage of its excellent hard X-ray spectral resolution...

  3. Graphical user interface for yield and dose estimations for cyclotron-produced technetium.

    Science.gov (United States)

    Hou, X; Vuckovic, M; Buckley, K; Bénard, F; Schaffer, P; Ruth, T; Celler, A

    2014-07-07

    The cyclotron-based (100)Mo(p,2n)(99m)Tc reaction has been proposed as an alternative method for solving the shortage of (99m)Tc. With this production method, however, even if highly enriched molybdenum is used, various radioactive and stable isotopes will be produced simultaneously with (99m)Tc. In order to optimize reaction parameters and estimate potential patient doses from radiotracers labeled with cyclotron produced (99m)Tc, the yields for all reaction products must be estimated. Such calculations, however, are extremely complex and time consuming. Therefore, the objective of this study was to design a graphical user interface (GUI) that would automate these calculations, facilitate analysis of the experimental data, and predict dosimetry. The resulting GUI, named Cyclotron production Yields and Dosimetry (CYD), is based on Matlab®. It has three parts providing (a) reaction yield calculations, (b) predictions of gamma emissions and (c) dosimetry estimations. The paper presents the outline of the GUI, lists the parameters that must be provided by the user, discusses the details of calculations and provides examples of the results. Our initial experience shows that the proposed GUI allows the user to very efficiently calculate the yields of reaction products and analyze gamma spectroscopy data. However, it is expected that the main advantage of this GUI will be at the later clinical stage when entering reaction parameters will allow the user to predict production yields and estimate radiation doses to patients for each particular cyclotron run.

  4. The smooth cyclotron line in her x-1 as seen with nuclear spectroscopic telescope array

    DEFF Research Database (Denmark)

    Fuerst, Felix; Grefenstette, Brian W.; Staubert, Ruediger

    2013-01-01

    Her X-1, one of the brightest and best studied X-ray binaries, shows a cyclotron resonant scattering feature (CRSF) near 37 keV. This makes it an ideal target for detailed study with the Nuclear Spectroscopic Telescope Array (NuSTAR), taking advantage of its excellent hard X-ray spectral resolution...

  5. Dispersion equations for field-aligned cyclotron waves in axisymmetric magnetospheric plasmas

    Directory of Open Access Journals (Sweden)

    N. I. Grishanov

    2006-03-01

    Full Text Available In this paper, we derive the dispersion equations for field-aligned cyclotron waves in two-dimensional (2-D magnetospheric plasmas with anisotropic temperature. Two magnetic field configurations are considered with dipole and circular magnetic field lines. The main contribution of the trapped particles to the transverse dielectric permittivity is estimated by solving the linearized Vlasov equation for their perturbed distribution functions, accounting for the cyclotron and bounce resonances, neglecting the drift effects, and assuming the weak connection of the left-hand and right-hand polarized waves. Both the bi-Maxwellian and bi-Lorentzian distribution functions are considered to model the ring current ions and electrons in the dipole magnetosphere. A numerical code has been developed to analyze the dispersion characteristics of electromagnetic ion-cyclotron waves in an electron-proton magnetospheric plasma with circular magnetic field lines, assuming that the steady-state distribution function of the energetic protons is bi-Maxwellian. As in the uniform magnetic field case, the growth rate of the proton-cyclotron instability (PCI in the 2-D magnetospheric plasmas is defined by the contribution of the energetic ions/protons to the imaginary part of the transverse permittivity elements. We demonstrate that the PCI growth rate in the 2-D axisymmetric plasmasphere can be significantly smaller than that for the straight magnetic field case with the same macroscopic bulk parameters.

  6. Tomsk Polytechnic University cyclotron as a source for neutron based cancer treatment.

    Science.gov (United States)

    Lisin, V A; Bogdanov, A V; Golovkov, V M; Musabaeva, L I; Sukhikh, L G; Verigin, D A

    2014-02-01

    In this paper we present our cyclotron based neutron source with average energy 6.3 MeV generated during the 13.6 MeV deuterons interactions with beryllium target, neutron field dosimetry, and dosimetry of attendant gamma fields. We also present application of our neutron source for cancer treatment.

  7. Three-wave interaction during electron cyclotron resonance heating and current drive

    DEFF Research Database (Denmark)

    Nielsen, Stefan Kragh; Jacobsen, Asger Schou; Hansen, Søren Kjer

    2016-01-01

    Non-linear wave-wave interactions in fusion plasmas, such as the parametric decay instability (PDI) of gyrotron radiation, can potentially hamper the use of microwave diagnostics. Here we report on anomalous scattering in the ASDEX Upgrade tokamak during electron cyclotron resonance heating...

  8. The electrostatic ion-cyclotron instability excited by a current to a strip collector

    DEFF Research Database (Denmark)

    Juul Rasmussen, Jens; Schrittwieser, R.; Skøelv, Å.

    1986-01-01

    The electrostatic ion-cyclotron instability is excited in a single-ended Q-machine by drawing an electron current to a strip collector crossing the entire plasma column. The instability is most easily excited when the widths of the strip is a few ion Larmor radii. The instability is confined within...

  9. Estimation of activity of air in the cyclotron bunker for PET diagnostics

    Directory of Open Access Journals (Sweden)

    Voskanjan Karen Varuzhanovich

    2012-09-01

    Full Text Available The paper presents the results of the estimation of air activation by argon-41 induced by accelerated protons in 18 MeV Cyclotron. It has been demonstrated that activity of air is below significant minimum at proton current of 150 microamps.

  10. Discrete-Spectrum Waves in the Vicinity of Cyclotron Resonance in Silver

    DEFF Research Database (Denmark)

    Henningsen, J. O.

    1970-01-01

    Cyclotron-resonance studies of silver have revealed two additional series of oscillations, one between the fundamental and the second harmonic, the other above the fundamental resonance. These series are caused by the excitation of weakly damped discrete-spectrum waves propagating perpendicular...

  11. Stability of electrostatic ion cyclotron waves in a multi-ion plasma

    Indian Academy of Sciences (India)

    A detailed numerical study, for parameters relevant to comet Halley, shows that the growth rate is dependent on the magnitude of the frequency. The ion cyclotron waves are driven by the electron drift parallel to the magnetic field; the temperature anisotropy of the oxygen ions only slightly enhance the growth rates for small ...

  12. On-line microseparations with Fourier transform ion cyclotron resonance mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Wahl, J.H.; Hofstadler, S.A.; Zhao, Zhongxi; Gale, D.C.; Smith, R.D. [Pacific Northwest Lab., Richland, WA (United States)

    1994-12-31

    The combination of capillary electrophoresis (CE) with electrospray ionization mass spectrometry (ESI/MS) is a powerful bioanalytical tool. Accurate charge states are readily obtained through high resolution MS techniques such as Fourier transform ion cyclotron resonance (FTICR) mass spectrometry. In this study, the authors examine the practical considerations that were necessary for successful on-line CE-ESI/FTICR MS.

  13. Theory of the Current-Driven Ion Cyclotron Instability in the Bottomside Ionosphere.

    Science.gov (United States)

    1985-11-11

    Davidson, 1972; Aamodt , 1970]. Recent nonlinear numerical simulations [Pritchett et al., 1981; Okuda and Ashour-Abdalla, 1981] of the collisionless ion...Y -.- d-. .-. .--. W REFERENCES Aamodt , R.E., Particle motion in the presence of three dimensional finite amplitude harmonic cyclotron

  14. Simulation on the electronic wave packet cyclotron motion in a Weyl semimetal slab.

    Science.gov (United States)

    Yao, Haibo; Zhu, Mingfeng; Jiang, Liwei; Zheng, Yisong

    2017-04-20

    We perform a numerical simulation on the time evolution of an electronic wave packet in a Weyl semimetal (WSM) slab driven by a magnetic field. We find that the evolution trajectory of the wave packet depends sensitively on its initial spin state. Only with initial spin state identical to that of the Fermi arc state at the surface it localized, does the wave packet evolution demonstrate the characteristic cyclotron orbit of WSM previously predicted from a semiclassical viewpoint. By analyzing the eigen-expansion of the electronic wave packet, we find the chiral Landau levels (LLs) of the WSM slab, as ingredients of the wave packet, to be responsible for establishing the characteristic WSM cyclotron orbit. In contrast, the nonchiral LLs contribute irregular oscillations to the wave packet evolution, going against the formation of a well-defined cyclotron orbit. In addition, the tilted magnetic field does not affect the motion of the electronic wave packet along the Fermi arcs in the momentum space. It does, however, alter the evolution trajectory of the electronic wave packet in real space and spin space. Finally, the energy disalignment of the Weyl nodes results in a 3D cyclotron orbit in real space.

  15. Closure of the single fluid magnetohydrodynamic equations in presence of electron cyclotron current drive

    NARCIS (Netherlands)

    Westerhof, E.; Pratt, J.

    2014-01-01

    In the presence of electron cyclotron current drive (ECCD), the Ohm's law of single fluid magnetohydrodynamics is modified as E + v × B = η(J – J EC). This paper presents a new closure relation for the EC driven current density appearing in this modified Ohm's law. The new relation

  16. Advanced launcher design options for electron cyclotron current drive on ITER based on remote steering

    NARCIS (Netherlands)

    Graswinckel, M. R.; Bongers, W. A.; M.R. de Baar,; van den Berg, M. A.; Denisov, G.; Donne, A. J. H.; Elzendoorn, B. S. Q.; Goede, A. P. H.; Heidinger, R.; Kuzikov, S.; Kruijt, O. G.; Kruizinga, B.; Moro, A.; Poli, E.; Ronden, D. M. S.; Saibene, G.; Thoen, D. J.; Verhoeven, A. G. A.

    2008-01-01

    Electron cyclotron current drive will become the main scheme on ITER for the stabilization of neoclassical tearing modes (NTMs) and the control of sawtooth oscillations. The effectiveness of this scheme forms the basis for the requirements of the ITER Upper Port Launcher. These requirements include

  17. Cyclotron laboratory of the Institute for Nuclear Research and Nuclear Energy

    Science.gov (United States)

    Tonev, D.; Goutev, N.; Georgiev, L. S.

    2016-06-01

    An accelerator laboratory is presently under construction in Sofia at the Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences. The laboratory will use a TR24 type of cyclotron, which provides a possibility to accelerate a proton beam with an energy of 15 to 24 MeV and current of up to 0.4 mA. An accelerator with such parameters allows to produce a large variety of radioisotopes for development of radiopharmaceuticals. The most common radioisotopes that could be produced with such a cyclotron are PET isotopes like: 11C, 13N, 15O, 18F, 124I, 64Cu, 68Ge/68Ga, and SPECT isotopes like: 123I, 111In, 67Ga, 57Co, 99m Tc. Our aim is to use the cyclotron facility for research in the fields of radiopharmacy, radiochemistry, radiobiology, nuclear physics, solid state physics, applied research, new materials and for education in all these fields including nuclear energy. The building of the laboratory will be constructed nearby the Institute for Nuclear Research and Nuclear Energy and the cyclotron together with all the equipment needed will be installed there.

  18. Neutron Beams from Deuteron Breakup at the 88-Inch Cyclotron at Lawrence Berkeley National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    McMahan, M.A.; Ahle, L.; Bleuel, D.L.; Bernstein, L.; Braquest, B.R.; Cerny, J.; Heilbronn, L.H.; Jewett, C.C.; Thompson, I.; Wilson, B.

    2007-07-31

    Accelerator-based neutron sources offer many advantages, in particular tunability of the neutron beam in energy and width to match the needs of the application. Using a recently constructed neutron beam line at the 88-Inch Cyclotron at LBNL, tunable high-intensity sources of quasi-monoenergetic and broad spectrum neutrons from deuteron breakup are under development for a variety of applications.

  19. Ultralow Frequency Waves In Saturn's Magnetosphere: More Than Ion Cyclotron Waves

    Science.gov (United States)

    Crary, Frank; Dols, Vincent; Usanova, Maria; Meeks, Zachary; Simon, Sven

    2017-04-01

    Electromagnetic waves near the oxygen/water group cyclotron frequency are an ubiquitous feature of Saturn's inner magnetosphere. These left-circularly polarized, transverse waves are generated by the anisotropic velocity distribution of recently produced ions, and reflect the ion production rate. The properties and distribution of these emissions have been previous studies and related to the distribution of neutrals in the system (Leisner et al., 2006; Crary et al., 2013; Meeks et al., 2016.) In addition to these waves, other, related mode have been observed by the Cassini spacecraft. The waves near the W+ (water group) cyclotron frequency sometimes have a compressional component and/or accompanying emission the first (2f) harmonic (implying the waves are oblique rather than parallel propagating. Neither of these properties is predicted by the classic theory of wave growth from a ring-beam distribution. In addition, ion cyclotron waves are also observed near the gyrofrequency of a 32 AMU ion, suggesting production of O2+. While observed, O2+ is a very low abundance species outside of 4 Saturn radii, and in the regions where these waves are present. Finally, strong but linearly polarized waves are sometimes observed near the orbit of Enceladus. The association between these waves and W+ ion cyclotron waves is unclear. We will present the measurements of these ULF waves, their frequency of occurrence with respect to position and time, and discuss their implications for plasma production in Saturn's magnetosphere.

  20. Techniques and mechanisms applied in electron cyclotron resonance sources for highly charged ions

    NARCIS (Netherlands)

    Drentje, AG

    Electron cyclotron resonance ion sources are delivering beams of highly charged ions for a wide range of applications in many laboratories. For more than two decades, the development of these ion sources has been to a large extent an intuitive and experimental enterprise. Much effort has been spent

  1. Electron cyclotron emission measurements on JET: Michelson interferometer, new absolute calibration, and determination of electron temperature

    NARCIS (Netherlands)

    Schmuck, S.; Fessey, J.; Gerbaud, T.; Alper, B.; Beurskens, M. N. A.; de la Luna, E.; Sirinelli, A.; Zerbini, M.

    2012-01-01

    At the fusion experiment JET, a Michelson interferometer is used to measure the spectrum of the electron cyclotron emission in the spectral range 70-500 GHz. The interferometer is absolutely calibrated using the hot/cold technique and, in consequence, the spatial profile of the plasma electron

  2. Three-dimensional simulations of ion dynamics in an Electron Cyclotron Resonance Ion Source

    NARCIS (Netherlands)

    Beijers, J. P. M.; Mironov, V.

    We present a three-dimensional simulation of the ion dynamics in an electron cyclotron resonance ion source. Ion trajectories in the min-B field of the source are calculated taking ion-ion and electron-ion collisions into account. The electrons are not tracked but considered as a neutralizing

  3. Abrupt variation in ion current with biased disk voltage in the electron cyclotron resonance ion source

    NARCIS (Netherlands)

    Taki, GS; Sarma, PR; Chakraborty, DK; Lhandari, RK; Ray, PK; Drentje, AG; Bhandari, R.K.

    The performance of the biased disk in the 6.4 GHz electron cyclotron resonance ion source at VECC, Kolkata was studied at a pressure of similar to 1 X 10(-7) Torr. We observed an abrupt variation of beam current with bias voltage. For low negative bias voltages (from 0 to -5 V) the beam current

  4. Experiments with biased cylinder in electron cyclotron resonance ion source (plenary)

    NARCIS (Netherlands)

    Drentje, AG; Kitagawa, A; Muramatsu, M; Ogawa, H; Sakamoto, Y

    The shape of the magnetic field of an electron cyclotron resonance ion source (ECRIS) gives rise to different particle fluxes (losses) from the plasma to the end plates (mainly diffusion of electrons), and to the side walls (mainly ions). The electron fluxes to the injection end plate can be reduced

  5. Selective minority-ion heating in the afterglow of an electron cyclotron resonance ion source

    NARCIS (Netherlands)

    Nadzeyka, A; Meyer, D; Barzangy, F; Drentje, AG; Wiesemann, K

    We report first experimental results on selective minority-ion heating in the afterglow mode of electron cyclotron resonance ion sources in Bochum and at the KVI (Groningen) in mixtures of Ar/O/He and in pure nitrogen. In addition we measured time resolved vacuum ultraviolet-line intensities of

  6. Isotopic anomaly for carbon ions in an electron cyclotron resonance ion source

    NARCIS (Netherlands)

    Drentje, A. G.; Kitagawa, A.; Muramatsu, M.

    In many experiments methods were applied to increase the highly charged ion output from an electron cyclotron resonance ion source; the gas-mixing method is still generally being applied. The dominant role of the masses of the ions in the gas-mixture was apparent. Two basically differing mechanisms

  7. An overview of control system for the ITER electron cyclotron system

    NARCIS (Netherlands)

    Purohit, D.; Bigelow, T.; Billava, D.; Bonicelli, T.; Caughman, J.; Darbos, C.; Denisov, G.; Gandini, F.; Gassmann, T.; Henderson, M.; Journeux, J. Y.; Kajiwara, K.; Kobayashi, N.; Nazare, C.; Oda, Y.; Omori, T.; Rao, S. L.; Rasmussen, D.; Ronden, D.; Saibene, G.; Sakamoto, K.; Sartori, F.; Takahashi, K.; Temkin, R.

    2011-01-01

    The ITER electron cyclotron (EC) system having capability of up to 26 MW generated power at 170 GHz is being procured by 5 domestic agencies via 10 procurement arrangements. This implies diverse types of equipment and complex interface management. It also places a challenge on control system

  8. Stability of electrostatic ion cyclotron waves in a multi-ion plasma†

    Indian Academy of Sciences (India)

    Abstract. We have studied the stability of the electrostatic ion cyclotron wave in a plasma consisting of isotropic hydrogen ions (H+) and temperature-anisotropic positively. (O+) and negatively (O−) charged oxygen ions, with the electrons drifting parallel to the magnetic field. Analytical expressions have been derived for the ...

  9. Ion cyclotron waves during the Rosetta approach phase: a magnetic estimate of cometary outgassing

    Directory of Open Access Journals (Sweden)

    M. Volwerk

    2013-12-01

    Full Text Available A theoretical model for the ion cyclotron wave generation during the approach phase of Rosetta to 67P/Churyumov–Gerasimenko is presented. For various activity levels of the comet, the crossing of the observational threshold is determined, whose level is derived from the wave power in the undisturbed solar wind near the comet's location during the approach phase at the appropriate frequency. The Giotto flyby at 27P/Grigg–Skjellerup is used to obtain an estimate of how often water-group ion cyclotron waves are observed, and to get insight into the wave forms. At 67P/Churyumov–Gerasimenko one can expect to observe water-group ion cyclotron waves already at a distance of 600 000 km from the nucleus for a nominal outgassing rate of Q = 350 × 1023 molecules per second. The observed first location of cyclotron waves during the Rosetta approach phase will give an indication of the actual outgassing rate of the comet.

  10. Graphical user interface for yield and dose estimations for cyclotron-produced technetium

    Science.gov (United States)

    Hou, X.; Vuckovic, M.; Buckley, K.; Bénard, F.; Schaffer, P.; Ruth, T.; Celler, A.

    2014-07-01

    The cyclotron-based 100Mo(p,2n)99mTc reaction has been proposed as an alternative method for solving the shortage of 99mTc. With this production method, however, even if highly enriched molybdenum is used, various radioactive and stable isotopes will be produced simultaneously with 99mTc. In order to optimize reaction parameters and estimate potential patient doses from radiotracers labeled with cyclotron produced 99mTc, the yields for all reaction products must be estimated. Such calculations, however, are extremely complex and time consuming. Therefore, the objective of this study was to design a graphical user interface (GUI) that would automate these calculations, facilitate analysis of the experimental data, and predict dosimetry. The resulting GUI, named Cyclotron production Yields and Dosimetry (CYD), is based on Matlab®. It has three parts providing (a) reaction yield calculations, (b) predictions of gamma emissions and (c) dosimetry estimations. The paper presents the outline of the GUI, lists the parameters that must be provided by the user, discusses the details of calculations and provides examples of the results. Our initial experience shows that the proposed GUI allows the user to very efficiently calculate the yields of reaction products and analyze gamma spectroscopy data. However, it is expected that the main advantage of this GUI will be at the later clinical stage when entering reaction parameters will allow the user to predict production yields and estimate radiation doses to patients for each particular cyclotron run.

  11. Wide-aperture Nonintercepting Ionization Sensor For Cyclotron Beam Cross-section Control

    CERN Document Server

    Latushkin, S T; Unezhev, V N; Yudin, L

    2004-01-01

    A new construction of beam cross-section ionization sensor (BCSIS) for use with intense beams is proposed. The aperture of the sensor was increased up to 120×120 mm, and its field of vision - up to 60×60 mm. The sensor is functioning at cyclotron with proton beam energy 32 MeV and current 20 mcA.

  12. Low current performance of the Bern medical cyclotron down to the pA range

    Science.gov (United States)

    Auger, M.; Braccini, S.; Ereditato, A.; Nesteruk, K. P.; Scampoli, P.

    2015-09-01

    A medical cyclotron accelerating H- ions to 18 MeV is in operation at the Bern University Hospital (Inselspital). It is the commercial IBA 18/18 cyclotron equipped with a specifically conceived 6 m long external beam line ending in a separate bunker. This feature is unique for a hospital-based facility and makes it possible to conduct routine radioisotope production for PET diagnostics in parallel with multidisciplinary research activities, among which are novel particle detectors, radiation biophysics, radioprotection, radiochemistry and radiopharmacy developments. Several of these activities, such as radiobiology experiments for example, require low current beams down to the pA range, while medical cyclotrons are designed for high current operation above 10 μA. In this paper, we present the first results on the low current performance of a PET medical cyclotron obtained by ion source, radio-frequency and main coil tuning. With this method, stable beam currents down to (1.5+/- 0.5 ) pA were obtained and measured with a high-sensitivity Faraday cup located at the end of the beam transport line.

  13. A remotely steered millimetre wave launcher for electron cyclotron heating and current drive on ITER

    NARCIS (Netherlands)

    Bongers, W. A.; M. F. Graswinckel,; Goede, A. P. H.; Kasparek, W.; Danilov, I.; Curto, A. F.; M.R. de Baar,; van den Berg, M. A.; Donne, A. J. H.; Elzendoorn, B. S. Q.; Heidinger, R.; Ivanov, P.; Kruijt, O. G.; Lamers, B.; Meier, A.; Piosczyk, B.; Plaum, B.; Ronden, D. M. S.; Thoen, D. J.; Schmid, M.; Verhoeven, A. G. A.

    2010-01-01

    High-power millimetre wave beams employed on ITER for heating and Current drive at the 170 GHz electron cyclotron resonance frequency require agile steering and tight focusing of the beams to suppress neoclassical tearing modes. This paper presents experimental validation of the remote steering (RS)

  14. Radiologic assessment of a self-shield with boron-containing water for a compact medical cyclotron.

    Science.gov (United States)

    Horitsugi, Genki; Fujibuchi, Toshioh; Yamaguchi, Ichiro; Eto, Akihisa; Iwamoto, Yasuo; Hashimoto, Hiromi; Hamada, Seiki; Obara, Satoshi; Watanabe, Hiroshi; Hatazawa, Jun

    2012-07-01

    The cyclotron at our hospital has a self-shield of boron-containing water. The amount of induced radioactivity in the boron-containing water shield of a compact medical cyclotron has not yet been reported. In this study, we measured the photon and neutron dose rates outside the self-shield during cyclotron operation. We estimated the induced radioactivities of the boron-containing water used for the self-shield and then measured them. We estimated the activation of concrete outside the self-shield in the cyclotron laboratory. The thermal neutron flux during cyclotron operation was estimated to be 4.72 × 10(2) cm(-2) s(-1), and the activation of concrete in a cyclotron laboratory was about three orders of magnitude lower than the clearance level of RS-G-1.7 (IAEA). The activity concentration of the boron-containing water did not exceed the concentration limit for radioactive isotopes in drainage in Japan and the exemption level for Basic Safety Standards. Consequently, the boron-containing water is treatable as non-radioactive waste. Neutrons were effectively shielded by the self-shield during cyclotron operation.

  15. Valorización del arte en los textos periodísticos de Clarice Lispector y Sara Gallardo (1967-1973

    Directory of Open Access Journals (Sweden)

    Guillermina Feudal

    2017-12-01

    Full Text Available En el contexto regional de democratización en el acceso a los bienes culturales, un aspecto nuclear de la producción periodística de Clarice Lispector y Sara Gallardo revela una sintonía común en el comentario y apropiación de recursos estéticos de las vanguardias “de los sesenta”. La apelación al arte como referencia para evaluar la vida cotidiana constituye una decisión comunicacional que funciona, desde el planteo formal y temático, como eje de las intervenciones críticas que ellas operan en el periodismo. El artículo analiza y compara la fundamentación de las elecciones artísticas de las autoras, así como los universos de discusión en los que desarrollan la contienda estética y debaten sobre los alcances de las nuevas modalidades de interacción cultural.

  16. A Kinetic Model of Solar Wind Generation by Oblique Ion-cyclotron Waves

    Science.gov (United States)

    Isenberg, Philip A.; Vasquez, Bernard J.

    2011-04-01

    The fast solar wind is generated by extended perpendicular ion heating in coronal holes, but the kinetic mechanism responsible for this heating has not been determined. One long-standing possibility is the resonant-cyclotron dissipation of ion-cyclotron waves, replenished from a turbulent cascade of interacting counter-propagating Alfvén waves. We present results of a kinetic model for proton heating by the quasilinear resonant-cyclotron wave-particle interaction in a coronal hole. The resonant wave spectrum is taken as a power law in wavenumber, uniformly distributed in propagation direction between 0° and 60° with respect to the large-scale radial magnetic field. We obtain the steady-state solution of the kinetic guiding-center equation for the proton distribution in an expanding coronal hole, including the effects of large-scale forces of gravity, charge-separation electric field, Alfvén wave ponderomotive force, and mirror force, along with the small-scale scattering from the wave dissipation. We find that plausible wave intensities can yield reasonable flow speeds and temperatures in the heliocentric radial range between 2 and 6 solar radii. We address the claim in earlier work that dissipation of parallel-propagating ion-cyclotron waves cannot provide enough acceleration and show that claim to be incorrect. We find that the combined action of the large-scale forces and the resonant-cyclotron scattering produces proton distribution functions with a characteristic structure: compressed in the sunward half of velocity space with a high-density shell separate from the origin, and relatively expanded in the anti-sunward half of velocity space. We suggest that qualitatively similar proton distributions would result from the kinetic evolution of any sufficiently effective perpendicular heating mechanism operating in an expanding coronal hole.

  17. Experimental measurement and Monte Carlo assessment of Argon-41 production in a PET cyclotron facility.

    Science.gov (United States)

    Infantino, Angelo; Valtieri, Lorenzo; Cicoria, Gianfranco; Pancaldi, Davide; Mostacci, Domiziano; Marengo, Mario

    2015-12-01

    In a medical cyclotron facility, (41)Ar (t1/2 = 109.34 m) is produced by the activation of air due to the neutron flux during irradiation, according to the (40)Ar(n,γ)(41)Ar reaction; this is particularly relevant in widely diffused high beam current cyclotrons for the production of PET radionuclides. While theoretical estimations of the (41)Ar production have been published, no data are available on direct experimental measurements for a biomedical cyclotron. In this work, we describe a sampling methodology and report the results of an extensive measurement campaign. Furthermore, the experimental results are compared with Monte Carlo simulations performed with the FLUKA code. To measure (41)Ar activity, air samples were taken inside the cyclotron bunker in sealed Marinelli beakers, during the routine production of (18)F with a 16.5 MeV GE-PETtrace cyclotron; this sampling thus reproduces a situation of absence of air changes. Samples analysis was performed in a gamma-ray spectrometry system equipped with HPGe detector. Monte Carlo assessment of the (41)Ar saturation yield was performed directly using the standard FLUKA score RESNUCLE, and off-line by the convolution of neutron fluence with cross section data. The average (41)Ar saturation yield per one liter of air of (41)Ar, measured in gamma-ray spectrometry, resulted to be 3.0 ± 0.6 Bq/µA*dm(3) while simulations gave a result of 6.9 ± 0.3 Bq/µA*dm(3) in the direct assessment and 6.92 ± 0.22 Bq/µA*dm(3) by the convolution neutron fluence-to-cross section. Copyright © 2015 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

  18. Production of high intensity 48Ca for the 88-Inch Cyclotron and other updates.

    Science.gov (United States)

    Benitez, J Y; Franzen, K Y; Hodgkinson, A; Lyneis, C M; Strohmeier, M; Thullier, T; Todd, D; Xie, D

    2014-02-01

    Recently the Versatile ECR for NUclear Science (VENUS) ion source was engaged in a 60-day long campaign to deliver high intensity (48)Ca(11+) beam to the 88-Inch Cyclotron. As the first long term use of VENUS for multi-week heavy-element research, new methods were developed to maximize oven to target efficiency. First, the tuning parameters of VENUS for injection into the cyclotron proved to be very different than those used to tune VENUS for maximum beam output of the desired charge state immediately following its bending magnet. Second, helium with no oxygen support gas was used to maximize the efficiency. The performance of VENUS and its low temperature oven used to produce the stable requested 75 eμA of (48)Ca(11+) beam current was impressive. The consumption of (48)Ca in VENUS using the low temperature oven was checked roughly weekly, and was found to be on average 0.27 mg/h with an ionization efficiency into the 11+ charge state of 5.0%. No degradation in performance was noted over time. In addition, with the successful operation of VENUS the 88-Inch cyclotron was able to extract a record 2 pμA of (48)Ca(11+), with a VENUS output beam current of 219 eμA. The paper describes the characteristics of the VENUS tune used for maximum transport efficiency into the cyclotron as well as ongoing efforts to improve the transport efficiency from VENUS into the cyclotron. In addition, we briefly present details regarding the recent successful repair of the cryostat vacuum system.

  19. Cyclotron resonance in InAs/AlSb quantum wells in magnetic fields up to 45 T

    Energy Technology Data Exchange (ETDEWEB)

    Spirin, K. E., E-mail: spirink@ipmras.ru; Krishtopenko, S. S. [Russian Academy of Sciences, Institute for Physics of Microstructures (Russian Federation); Sadofyev, Yu. G. [Russian Academy of Sciences, Lebedev Physical Institute (Russian Federation); Drachenko, O. [Laboratoire National des Champs Magn’etiques Intenses (France); Helm, M. [Forschungszentrum Dresden–Rossendorf, Dresden High-Magnetic-Field Laboratory and Institute of Ion-Beam Physics and Materials Research (Germany); Teppe, F.; Knap, W. [GIS-TERALAB Universite Montpellier II, Laboratoire Charles Coulomb UMR CNRS 5221 (L2C) (France); Gavrilenko, V. I. [Russian Academy of Sciences, Institute for Physics of Microstructures (Russian Federation)

    2015-12-15

    Electron cyclotron resonance in InAs/AlSb heterostructures with quantum wells of various widths in pulsed magnetic fields up to 45 T are investigated. Our experimental cyclotron energies are in satisfactory agreement with the results of theoretical calculations performed using the eight-band kp Hamiltonian. The shift of the cyclotron resonance (CR) line, which corresponds to the transition from the lowest Landau level to the low magnetic-field region, is found upon varying the electron concentration due to the negative persistent photoconductivity effect. It is shown that the observed shift of the CR lines is associated with the finite width of the density of states at the Landau levels.

  20. Ion cyclotron waves at unmagnetized bodies: a comparison of Mars, Venus and Titan

    Science.gov (United States)

    Wei, H.; Russell, C. T.; Cowee, M.; Blanco-Cano, X.; Zhang, T.; Dougherty, M. K.

    2009-12-01

    Mars, Venus and Titan do not have appreciable global magnetic fields. Their high-altitude neutral atmospheres are not shielded from being lost to the solar wind and the Saturnian magnetosphere. When the atmospheric hydrogen atoms of Mars and Venus are ionized and picked up by the solar wind, proton cyclotron waves are created from the free energy of the ring-beam distribution of the pick-up ions. At Mars, proton cyclotron waves observed by Mars Global Surveyor extend from the magnetosheath to over 12 Mars radii, with intermittent occurrence and amplitudes slowly varying with distance. The wave occurrence pattern indicates a disk-shaped hydrogen exosphere of Mars with asymmetry in the direction of the interplanetary electric field. Fast neutrals produced by neutralization of the pickup ions can travel across fieldlines to distant regions where they get re-ionized and produce waves far downstream. Thus the top of Mars exosphere extends in a disk to high altitude, with its orientation controlled by the interplanetary magnetic field. At Venus, plasma waves having properties similar to ion cyclotron waves are observed in the solar wind around the planet by Venus Express, with wave frequencies that range from 0.2 to 5.9 times of the proton gyrofrequency. Statistical study shows that the waves with frequency higher than 1.5 times the proton gyrofrequency are not generated locally and are similar to the waves observed at 0.3 AU and 1 AU which appear to be created near the Sun and convected outward with the solar wind. The rest of the waves are mostly magnetically connected to the bow shock, so they are probably generated by particles backstreaming from the shock and propagate out further from the foreshock. At Titan, ion cyclotron waves are not observed although wave generation is expected due to the large pickup rate of hydrocarbon ions at high altitude of Titan. We attempt to understand the lack of ion cyclotron waves at Titan using hybrid simulations. Studying and