WorldWideScience

Sample records for sap electronic resource

  1. 30 CFR 285.607 - How do I submit my SAP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How do I submit my SAP? 285.607 Section 285.607... Assessment Plan and Information Requirements for Commercial Leases § 285.607 How do I submit my SAP? You must submit one paper copy and one electronic version of your SAP to MMS at the address listed in § 285.110(a). ...

  2. Shared access protocol (SAP) in femtocell channel resources for cellular coverage enhancement

    KAUST Repository

    Magableh, Amer M.

    2012-12-01

    Femtocells are promising techniques employed in cellular systems to enhance the indoor coverage, especially in areas with high density and high traffic rates. In this paper, we propose an efficient resource utilization protocol, named shared access protocol (SAP), that enables the unlicensed macro-cell user equipments (MC-UE) to communicate with partially closed access femtocell base stations and hence, improves and enhances the overall system performance in closed environments. For the proposed system model, we obtain, in closed-form, the main signal-to-interference plus noise ratio (SINR) characteristics, including the probability density function (PDF) and the cumulative distribution function (CDF). In addition, these expressions are further used to derive several performance metrics in closed-form, such as, the average bit error rate (BER), outage probability, and the average channel capacity for the proposed SAP herein. Furthermore, Monte-carlo simulations as well as numerical results are provided showing a good match that ensures and confirms the correctness of the derived expressions. © 2012 IEEE.

  3. 30 CFR 285.606 - What must I demonstrate in my SAP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I demonstrate in my SAP? 285.606 Section 285.606 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE... demonstrate in my SAP? (a) Your SAP must demonstrate that you have planned and are prepared to conduct the...

  4. Integrating Enterprise Resource Planning (SAP) in the Accounting Curriculum: A Systematic Literature Review and Case Study

    Science.gov (United States)

    Blount, Yvette; Abedin, Babak; Vatanasakdakul, Savanid; Erfani, Seyedezahra

    2016-01-01

    This study investigates how an enterprise resource planning (ERP) software package SAP was integrated into the curriculum of an accounting information systems (AIS) course in an Australian university. Furthermore, the paper provides a systematic literature review of articles published between 1990 and 2013 to understand how ERP systems were…

  5. 30 CFR 285.605 - What is a Site Assessment Plan (SAP)?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What is a Site Assessment Plan (SAP)? 285.605... Assessment Plan (SAP)? (a) A SAP describes the activities (e.g., installation of meteorological towers... project easement, or to test technology devices. (1) Your SAP must describe how you will conduct your...

  6. 30 CFR 285.610 - What must I include in my SAP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What must I include in my SAP? 285.610 Section... Requirements Contents of the Site Assessment Plan § 285.610 What must I include in my SAP? Your SAP must... SAP, you must provide the following information: ER29AP09.115 (b) You must provide the results of...

  7. Implantación del sistema ERP SAP R/3

    OpenAIRE

    Muñoz Fernandez, Jorge Juan

    2012-01-01

    El objetivo del presente trabajo ha sido realizar un estudio de investigación y desarrollo sobre la implantación del sistema Enterprise Resource Planning (ERP) SAP R/3 de una empresa. L'objectiu d'aquest treball final de carrera ha estat realitzar un estudi d'investigació i desenvolupament sobre la implantació del sistema Enterprise Resource Planning (ERP) SAP R/3 d'una empresa.

  8. REA analysis of SAP HCM; some initial findings

    OpenAIRE

    Fallon, Richard; Polovina, Simon

    2013-01-01

    This paper explores further the claim that the Transaction-Oriented Architecture (TOA) based on the principles of Resources, Events, Agents (REA) can enhance Enterprise Resource Planning (ERP) systems by providing a principled theoretical basis that can underpin ERP business process implementations. We provide details of some of our initial findings of the REA/TOA analysis which we carried out on the SAP Human Capital Management (HCM) module. Given that SAP is recognized as the dominant ERP s...

  9. 30 CFR 285.613 - How will MMS process my SAP?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will MMS process my SAP? 285.613 Section... Requirements Contents of the Site Assessment Plan § 285.613 How will MMS process my SAP? (a) The MMS will review your submitted SAP, and additional information provided pursuant to § 285.611, to determine if it...

  10. Functional dependency between the logistics security system and the MySAP ERP in metallurgy

    Directory of Open Access Journals (Sweden)

    P. Ranitović

    2013-10-01

    Full Text Available MySAP ERP - Enterprise Resource Planning (system - solution which provides a whole set of functions for the business analytics, finance, human resources management, logistics and corporate services has developed from SAP R/3. It is one of the main products of the SAP AG German multinational company and as such, it is a very important element of the international industrial and technological security system. By defining the functional dependency between the security systems (logistics security systems and the IT (My SAP ERP systems in metallurgy, a concept for designing MY SAP ERP system in metallurgic industry is defined, based on the security aspects.

  11. 30 CFR 285.614 - When may I begin conducting activities under my approved SAP?

    Science.gov (United States)

    2010-07-01

    ... approved SAP? 285.614 Section 285.614 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE... Plans and Information Requirements Activities Under An Approved Sap § 285.614 When may I begin conducting activities under my approved SAP? (a) You may begin conducting the activities approved in your SAP...

  12. The efficiency of SAP in improving the HR performance case study ...

    African Journals Online (AJOL)

    The efficiency of SAP in improving the HR performance case study: Masdar ... administrative and strategic levels, as well as identifying the contribution of ... Keywords: SAP, human resources management, Masdar Building Materials Company ...

  13. Helium implantation effects in SAP and aluminum

    International Nuclear Information System (INIS)

    Bauer, W.; Thomas, G.J.

    1976-02-01

    A series of 300 keV He implantations of Al and SAP 930 have been conducted at temperatures between 150 and 773K. The He re-emission was monitored during implantation and the samples were examined with a scanning electron microscope after implantation. Both Al and SAP 930 were found to blister after a critical He dose was reached at temperatures above 473K, both underwent flaking below that temperature, with blistering re-appearing in SAP 930 at an implantation temperature of 150K. The surface deformation and He re-emission are strongly dependent on microstructural effects in the intermediate temperature regime

  14. Pembelajaran Mandiri Aplikasi Enterprise Resource System: Studi Kasus pada Aplikasi SAP – Modul Sales and Distribution

    Directory of Open Access Journals (Sweden)

    Johan Johan

    2013-12-01

    Full Text Available ERP (enterprise resource planning is a solution needed by companies to assist the integration of all functional areas. A self-learning media of ERP system is needed for the successful use which is highly depended on the users mastery. The learning media must be flexible to time and place. Therefore, this research creates a self-learning application for ERP system based on a case study on SAP application. SAP is an ERP-based solution widely used by medium to large companies. The method used are data collection, analysis on running business processes and the identification of information needs, followed by the application design. Identificationof system requirements uses Flash CS5 Action Script 3.0. The result achieved in this research is a multimediabased learning tool which assists training for trainers and trainee and facilitates trainee supervision during training. The learning tool is found helpful in self learning process.

  15. Functional dependency between the logistics security system and the MySAP ERP in metallurgy

    OpenAIRE

    Ranitović, P.; Tepić, G.; Matić, B.; Sremac, S.; Vukadinović, V.

    2013-01-01

    MySAP ERP - Enterprise Resource Planning (system - solution which provides a whole set of functions for the business analytics, finance, human resources management, logistics and corporate services) has developed from SAP R/3. It is one of the main products of the SAP AG German multinational company and as such, it is a very important element of the international industrial and technological security system. By defining the functional dependency between the security systems (logistics securit...

  16. Disruption of each of the secreted aspartyl proteinase genes SAP1, SAP2, and SAP3 of Candida albicans attenuates virulence.

    OpenAIRE

    Hube, B; Sanglard, D; Odds, F C; Hess, D; Monod, M; Schäfer, W; Brown, A J; Gow, N A

    1997-01-01

    Secreted aspartyl proteinases (Saps), encoded by a gene family with at least nine members (SAP1 to SAP9), are one of the most discussed virulence factors produced by the human pathogen Candida albicans. In order to study the role of each Sap isoenzyme in pathogenicity, we have constructed strains which harbor mutations at selected SAP genes. SAP1, SAP2, and SAP3, which are regulated differentially in vitro, were mutated by targeted gene disruption. The growth rates of all homozygous null muta...

  17. Projecte d'integració entre SAP GH - SAP MM - Kàrdex

    OpenAIRE

    Perea Núñez, Yolanda

    2012-01-01

    Projecte d'integració entre dos sistemes SAP (gestió hospitalària i gestió de materials) amb un altre sistema aliè a SAP, el sistema de magatzem de medicaments Kàrdex, mitjançant comunicacions via SAP Process Integration. Proyecto de integración entre dos sistemas SAP (gestión hospitalaria y gestión de materiales) con otro sistema ajeno a SAP, el sistema de almacén de medicamentos Kardex, mediante comunicaciones vía SAP Process Integration.

  18. Date palm sap collection: exploring opportunities to prevent Nipah transmission.

    Science.gov (United States)

    Nahar, Nazmun; Sultana, Rebeca; Gurley, Emily S; Hossain, M Jahangir; Luby, Stephen P

    2010-06-01

    Nipah virus (NiV) infection is a seasonal disease in Bangladesh that coincides with the date palm sap collection season. Raw date palm sap is a delicacy to drink in Bengali culture. If fruit bats that are infected with NiV gain access to the sap for drinking, they might occasionally contaminate the sap through saliva and urine. In February 2007, we conducted a qualitative study in six villages, interviewing 27 date palm sap collectors (gachhis) within the geographical area where NiV outbreaks have occurred since 2001. Gachhis reported that bats pose a challenge to successful collection of quality sap, because bats drink and defecate into the sap which markedly reduces its value. They know some methods to prevent access by bats and other pests but do not use them consistently, because of lack of time and resources. Further studies to explore the effectiveness of these methods and to motivate gachhis to invest their time and money to use them could reduce the risk of human Nipah infection in Bangladesh.

  19. Implementation of SAP Waste Management System

    International Nuclear Information System (INIS)

    Frost, M.L.; LaBorde, C.M.; Nichols, C.D.

    2008-01-01

    The Y-12 National Security Complex (Y-12) assumed responsibility for newly generated waste on October 1, 2005. To ensure effective management and accountability of newly generated waste, Y-12 has opted to utilize SAP, Y-12's Enterprise Resource Planning (ERP) tool, to track low-level radioactive waste (LLW), mixed waste (MW), hazardous waste, and non-regulated waste from generation through acceptance and disposal. SAP Waste will include the functionality of the current waste tracking system and integrate with the applicable modules of SAP already in use. The functionality of two legacy systems, the Generator Entry System (GES) and the Waste Information Tracking System (WITS), and peripheral spreadsheets, databases, and e-mail/fax communications will be replaced by SAP Waste. Fundamentally, SAP Waste will promote waste acceptance for certification and disposal, not storage. SAP Waste will provide a one-time data entry location where waste generators can enter waste container information, track the status of their waste, and maintain documentation. A benefit of the new system is that it will provide a single data repository where Y-12's Waste Management organization can establish waste profiles, verify and validate data, maintain inventory control utilizing hand-held data transfer devices, schedule and ship waste, manage project accounting, and report on waste handling activities. This single data repository will facilitate the production of detailed waste generation reports for use in forecasting and budgeting, provide the data for required regulatory reports, and generate metrics to evaluate the performance of the Waste Management organization and its subcontractors. SAP Waste will replace the outdated and expensive legacy system, establish tools the site needs to manage newly generated waste, and optimize the use of the site's ERP tool for integration with related business processes while promoting disposition of waste. (authors)

  20. The Efficiency of SAP in improving the HR Performance Case Study ...

    African Journals Online (AJOL)

    pc

    2018-03-05

    Mar 5, 2018 ... operations at the operational, administrative and strategic levels, as well as identifying ... Key Words- SAP, human resources management, Masdar. Building ... There are thousands of companies around the world using the SAP ... results indicate that managers have a fairly positive view of the impact of the ...

  1. Statistical characterization of the Sub-Auroral Polarization Stream (SAPS)

    Science.gov (United States)

    Kunduri, B.; Baker, J. B.; Ruohoniemi, J. M.; Erickson, P. J.; Coster, A. J.; Oksavik, K.

    2017-12-01

    The Sub-Auroral Polarization Stream (SAPS) is a narrow region of westward directed plasma convection typically observed in the dusk-midnight sector equatorward of the main auroral oval. SAPS plays an important role in mid-latitude space weather dynamics and has a controlling influence on the evolution of large-scale plasma features, such as Storm Enhanced Density (SED) plumes. In this study, data from North American mid-latitude SuperDARN radars collected between January 2011 and December 2014 have been used to compile a database of SAPS events for statistical analysis. We examine the dependence of SAPS velocity magnitude and direction on geomagnetic activity and magnetic local time. The lowest speed limit and electric fields observed during SAPS are discussed and histograms of SAPS velocities for different Dst bins and MLAT-MLT locations are presented. We find significant differences in SAPS characteristics between periods of low and high geomagnetic activity, suggesting that SAPS are driven by different mechanisms during storm and non-storm conditions. To further explore this possibility, we have characterized the SAPS location and peak speed relative to the ionospheric trough specified by GPS Total Electron Content (TEC) data from the MIT Haystack Madrigal database. A particular emphasis is placed on identifying the extent to which the location, structure, and depth of the trough may play a controlling influence on SAPS speeds during storm and non-storm periods. The results are interpreted in terms of the current paradigm for active thermosphere-ionosphere feedback being an important component of SAPS physics.

  2. Control objectives design for the human and resources module of SAP

    OpenAIRE

    Collado Antón, Jesús

    2010-01-01

    Català: En aquest projecte trobem la definició d'objectius de control i d'activitats de control per al módul de recursos humans de SAP, donant especial importància a l'adecuada segregació de funcions dins el módul. Castellano: En este proyecto de encuentra la definición de objetivos de control i actividades de control para el módulo de recursos humanos de SAP, dando especial importancia a la adecuada segregación de funciones dentro de éste módulo. English: In this project we can find th...

  3. SAP crm integration testing

    OpenAIRE

    Černiavskaitė, Marija

    2017-01-01

    This Bachelor's thesis presents SAP CRM and integration systems testing analysis: investigation in SAP CRM and SAP PO systems, presentation of relationship between systems, introduction to third-party system (non-SAP) – Network Informational System (NIS) which has integration with SAP, presentation of best CRM testing practises, analysis and recommendation of integration testing. Practical integration testing is done in accordance to recommendations.

  4. Xylem sap proteomics.

    Science.gov (United States)

    de Bernonville, Thomas Dugé; Albenne, Cécile; Arlat, Matthieu; Hoffmann, Laurent; Lauber, Emmanuelle; Jamet, Elisabeth

    2014-01-01

    Proteomic analysis of xylem sap has recently become a major field of interest to understand several biological questions related to plant development and responses to environmental clues. The xylem sap appears as a dynamic fluid undergoing changes in its proteome upon abiotic and biotic stresses. Unlike cell compartments which are amenable to purification in sufficient amount prior to proteomic analysis, the xylem sap has to be collected in particular conditions to avoid contamination by intracellular proteins and to obtain enough material. A model plant like Arabidopsis thaliana is not suitable for such an analysis because efficient harvesting of xylem sap is difficult. The analysis of the xylem sap proteome also requires specific procedures to concentrate proteins and to focus on proteins predicted to be secreted. Indeed, xylem sap proteins appear to be synthesized and secreted in the root stele or to originate from dying differentiated xylem cells. This chapter describes protocols to collect xylem sap from Brassica species and to prepare total and N-glycoprotein extracts for identification of proteins by mass spectrometry analyses and bioinformatics.

  5. A New Approach to Sap Flow Measurement Using 3D Printed Gauges and Open-source Electronics

    Science.gov (United States)

    Ham, J. M.; Miner, G. L.; Kluitenberg, G. J.

    2015-12-01

    A new type of sap flow gauge was developed to measure transpiration from herbaceous plants using a modified heat pulse technique. Gauges were fabricated using 3D-printing technology and low-cost electronics to keep the materials cost under $20 (U.S.) per sensor. Each gauge consisted of small-diameter needle probes fastened to a 3D-printed frame. One needle contained a resistance heater to provide a 6 to 8 second heat pulse while the other probes measured the resultant temperature increase at two distances from the heat source. The data acquisition system for the gauges was built from a low-cost Arduino microcontroller. The system read the gauges every 10 minutes and stored the results on a SD card. Different numerical techniques were evaluated for estimating sap velocity from the heat pulse data - including analytical solutions and parameter estimation approaches . Prototype gauges were tested in the greenhouse on containerized corn and sunflower. Sap velocities measured by the gauges were compared to independent gravimetric measurements of whole plant transpiration. Results showed the system could measure daily transpiration to within 3% of the gravimetric measurements. Excellent agreement was observed when two gauges were attached the same stem. Accuracy was not affected by rapidly changing transpiration rates observed under partly cloudy conditions. The gauge-based estimates of stem thermal properties suggested the system may also detect the onset of water stress. A field study showed the gauges could run for 1 to 2 weeks on a small battery pack. Sap flow measurements on multiple corn stems were scaled up by population to estimate field-scale transpiration. During full canopy cover, excellent agreement was observed between the scaled-up sap flow measurements and reference crop evapotranspiration calculated from weather data. Data also showed promise as a way to estimate real-time canopy resistance required for model verification and development. Given the low

  6. The relationship between sap-flow rate and sap volume in dormant sugar maples

    Science.gov (United States)

    William J. Gabriel; Russell S. Walters; Donald W. Seegrist

    1972-01-01

    Sap-flow rate is closely correlated with the sap volume produced by dormant sugar maple trees (Acer saccharum Marsh.) and could be used in making phenotypic selections of trees for superior sap production.

  7. 30 CFR 285.615 - What other reports or notices must I submit to MMS under my approved SAP?

    Science.gov (United States)

    2010-07-01

    ... MMS under my approved SAP? 285.615 Section 285.615 Mineral Resources MINERALS MANAGEMENT SERVICE... CONTINENTAL SHELF Plans and Information Requirements Activities Under An Approved Sap § 285.615 What other reports or notices must I submit to MMS under my approved SAP? (a) You must notify MMS in writing within...

  8. 7 CFR 1437.107 - Maple sap.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Maple sap. 1437.107 Section 1437.107 Agriculture... Yield Coverage Using Actual Production History § 1437.107 Maple sap. (a) NAP assistance for maple sap is limited to maple sap produced on private property for sale as sap or syrup. Eligible maple sap must be...

  9. 30 CFR 285.902 - What are the general requirements for decommissioning for facilities authorized under my SAP, COP...

    Science.gov (United States)

    2010-07-01

    ... decommissioning for facilities authorized under my SAP, COP, or GAP? 285.902 Section 285.902 Mineral Resources... SAP, COP, or GAP? (a) Except as otherwise authorized by MMS under § 285.909, within 2 years following... under your SAP, COP, or GAP, you must submit a decommissioning application and receive approval from the...

  10. 30 CFR 285.659 - What requirements must I include in my SAP, COP, or GAP regarding air quality?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What requirements must I include in my SAP, COP, or GAP regarding air quality? 285.659 Section 285.659 Mineral Resources MINERALS MANAGEMENT SERVICE... must I include in my SAP, COP, or GAP regarding air quality? (a) You must comply with the Clean Air Act...

  11. 30 CFR 285.612 - How will my SAP be processed for Federal consistency under the Coastal Zone Management Act?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false How will my SAP be processed for Federal consistency under the Coastal Zone Management Act? 285.612 Section 285.612 Mineral Resources MINERALS... Plan § 285.612 How will my SAP be processed for Federal consistency under the Coastal Zone Management...

  12. SAP

    DEFF Research Database (Denmark)

    Petersen, Bent; Nikerle-Uhthoff, Dominique; Schwaerzler, Helen

    2014-01-01

    In late 2011, SAP, the German leader in the enterprise software industry, announced a major investment plan for expanding in China and also acquired a leading American firm in cloud-based human capital management software. At first glance, these investments seemed rather unconnected. A closer look...... at SAP’s strategy, however, revealed a closely connected and coordinated network of strategic decisions and investments for which alignment and finding the right balance were key challenges. Hence, it was crucial to ask: What were the principal challenges for SAP in aligning its innovation and sourcing...

  13. Shared access protocol (SAP) in femtocell channel resources for cellular coverage enhancement

    KAUST Repository

    Magableh, Amer M.; Radaydeh, Redha Mahmoud Mesleh; Alouini, Mohamed-Slim

    2012-01-01

    protocol (SAP), that enables the unlicensed macro-cell user equipments (MC-UE) to communicate with partially closed access femtocell base stations and hence, improves and enhances the overall system performance in closed environments. For the proposed

  14. 30 CFR 285.700 - What reports must I submit to MMS before installing facilities described in my approved SAP, COP...

    Science.gov (United States)

    2010-07-01

    ... installing facilities described in my approved SAP, COP, or GAP? 285.700 Section 285.700 Mineral Resources... § 285.700 What reports must I submit to MMS before installing facilities described in my approved SAP... in your approved COP (§ 285.632(a)) and, when required by this part, your SAP (§ 285.614(b)) or GAP...

  15. SAPS, Crime statistics

    African Journals Online (AJOL)

    incidents' refer to 'incidents such as labour disputes and dissatisfaction with service delivery in which violence erupted and SAPS action was required to restore peace and order'.26. It is apparent from both the SAPS statistics and those provided by the Municipal IQ Hotspots. Monitor, that public protests and gatherings are.

  16. Measuring Complexity of SAP Systems

    Directory of Open Access Journals (Sweden)

    Ilja Holub

    2016-10-01

    Full Text Available The paper discusses the reasons of complexity rise in ERP system SAP R/3. It proposes a method for measuring complexity of SAP. Based on this method, the computer program in ABAP for measuring complexity of particular SAP implementation is proposed as a tool for keeping ERP complexity under control. The main principle of the measurement method is counting the number of items or relations in the system. The proposed computer program is based on counting of records in organization tables in SAP.

  17. Detoxification of Sap from Felled Oil Palm Trunks for the Efficient Production of Lactic Acid.

    Science.gov (United States)

    Kunasundari, Balakrishnan; Arai, Takamitsu; Sudesh, Kumar; Hashim, Rokiah; Sulaiman, Othman; Stalin, Natra Joseph; Kosugi, Akihiko

    2017-09-01

    The availability of fermentable sugars in high concentrations in the sap of felled oil palm trunks and the thermophilic nature of the recently isolated Bacillus coagulans strain 191 were exploited for lactic acid production under non-sterile conditions. Screening indicated that strain 191 was active toward most sugars including sucrose, which is a major component of sap. Strain 191 catalyzed a moderate conversion of sap sugars to lactic acid (53%) with a productivity of 1.56 g/L/h. Pretreatment of oil palm sap (OPS) using alkaline precipitation improved the sugar fermentability, providing a lactic acid yield of 92% and productivity of 2.64 g/L/h. To better characterize potential inhibitors in the sap, phenolic, organic, and mineral compounds were analyzed using non-treated sap and saps treated with activated charcoal and alkaline precipitation. Phthalic acid, 3,4-dimethoxybenzoic acid, aconitic acid, syringic acid, and ferulic acid were reduced in the sap after treatment. High concentrations of Mg, P, K, and Ca were also precipitated by the alkaline treatment. These results suggest that elimination of excess phenolic and mineral compounds in OPS can improve the fermentation yield. OPS, a non-food resource that is readily available in bulk quantities from plantation sites, is a promising source for lactic acid production.

  18. Analysis list: SAP30 [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available SAP30 Blood,Pluripotent stem cell + hg19 http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/SAP...30.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/target/SAP30.5.tsv http://dbarchive....biosciencedbc.jp/kyushu-u/hg19/target/SAP30.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/SAP...30.Blood.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/hg19/colo/SAP30.Pluripote

  19. [Validity of APACHE II, APACHE III, SAPS 2, SAPS 3 and SOFA scales in obstetric patients with sepsis].

    Science.gov (United States)

    Zabolotskikh, I B; Musaeva, T S; Denisova, E A

    2012-01-01

    to estimate efficiency of APACHE II, APACHE III, SAPS II, SAPS III, SOFA scales for obstetric patients with heavy sepsis. 186 medical cards retrospective analysis of pregnant women with pulmonary sepsis, 40 women with urosepsis and puerperas with abdominal sepsis--66 was performed. Middle age of women was 26.7 (22.4-34.5). In population of puerperas with abdominal sepsis APACHE II, APACHE III, SAPS 2, SAPS 3, SOFA scales showed to good calibration, however, high resolution was observed only in APACHE III, SAPS 3 and SOFA (AUROC 0.95; 0.93; 0.92 respectively). APACHE III and SOFA scales provided qualitative prognosis in pregnant women with urosepsis; resolution ratio of these scales considerably exceeds APACHE II, SAPS 2 and SAPS 3 (AUROC 0.73; 0.74; 0.79 respectively). APACHE II scale is inapplicable because of a lack of calibration (X2 = 13.1; p < 0.01), and at other scales (APACHE III, SAPS 2, SAPS 3, SOFA) was observed the insufficient resolution (AUROC < 0.9) in pregnant women with pulmonary sepsis. Prognostic possibilities assessment of score scales showed that APACHE III, SAPS 3 and SOFA scales can be used for a lethality prognosis for puerperas with abdominal sepsis, in population of pregnant women with urosepsis--only APACHE III and SOFA, and with pulmonary sepsis--SAPS 3 and APACHE III only in case of additional clinical information.

  20. Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity

    Science.gov (United States)

    Cai, Chenxu; Liu, Guangao; Wang, Yuande; Du, Juan; Lin, Xin; Yang, Meixiang

    2017-01-01

    Signaling lymphocytic activation molecule (SLAM)–associated protein (SAP) mutations in X-linked lymphoproliferative disease (XLP) lead to defective NKT cell development and impaired humoral immunity. Because of the redundancy of SLAM family receptors (SFRs) and the complexity of SAP actions, how SFRs and SAP mediate these processes remains elusive. Here, we examined NKT cell development and humoral immunity in mice completely deficient in SFR. We found that SFR deficiency severely impaired NKT cell development. In contrast to SAP deficiency, SFR deficiency caused no apparent defect in follicular helper T (TFH) cell differentiation. Intriguingly, the deletion of SFRs completely rescued the severe defect in TFH cell generation caused by SAP deficiency, whereas SFR deletion had a minimal effect on the defective NKT cell development in SAP-deficient mice. These findings suggest that SAP-dependent activating SFR signaling is essential for NKT cell selection; however, SFR signaling is inhibitory in SAP-deficient TFH cells. Thus, our current study revises our understanding of the mechanisms underlying T cell defects in patients with XLP. PMID:28049627

  1. Dissection of SAP-dependent and SAP-independent SLAM family signaling in NKT cell development and humoral immunity.

    Science.gov (United States)

    Chen, Shasha; Cai, Chenxu; Li, Zehua; Liu, Guangao; Wang, Yuande; Blonska, Marzenna; Li, Dan; Du, Juan; Lin, Xin; Yang, Meixiang; Dong, Zhongjun

    2017-02-01

    Signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) mutations in X-linked lymphoproliferative disease (XLP) lead to defective NKT cell development and impaired humoral immunity. Because of the redundancy of SLAM family receptors (SFRs) and the complexity of SAP actions, how SFRs and SAP mediate these processes remains elusive. Here, we examined NKT cell development and humoral immunity in mice completely deficient in SFR. We found that SFR deficiency severely impaired NKT cell development. In contrast to SAP deficiency, SFR deficiency caused no apparent defect in follicular helper T (T FH ) cell differentiation. Intriguingly, the deletion of SFRs completely rescued the severe defect in T FH cell generation caused by SAP deficiency, whereas SFR deletion had a minimal effect on the defective NKT cell development in SAP-deficient mice. These findings suggest that SAP-dependent activating SFR signaling is essential for NKT cell selection; however, SFR signaling is inhibitory in SAP-deficient T FH cells. Thus, our current study revises our understanding of the mechanisms underlying T cell defects in patients with XLP. © 2017 Chen et al.

  2. 30 CFR 285.611 - What information must I submit with my SAP to assist MMS in complying with NEPA and other...

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What information must I submit with my SAP to... Assessment Plan § 285.611 What information must I submit with my SAP to assist MMS in complying with NEPA and other relevant laws? (a) You must submit with your SAP detailed information to assist MMS in complying...

  3. Software development on the SAP HANA platform

    CERN Document Server

    Walker, Mark

    2013-01-01

    Software Development on the SAP HANA Platform is a general tutorial guide to SAP HANA.This book is written for beginners to the SAP HANA platform. No knowledge of SAP HANA is necessary to start using this book.

  4. Binding of complement proteins C1q and C4bp to serum amyloid P component (SAP) in solid contra liquid phase

    DEFF Research Database (Denmark)

    Sørensen, Inge Juul; Nielsen, EH; Andersen, Ove

    1996-01-01

    Serum amyloid P component (SAP), a member of the conserved pentraxin family of plasma proteins, binds calcium dependently to its ligands. The authors investigated SAPs interaction with the complement proteins C4b binding protein (C4bp) and C1q by ELISA, immunoelectrophoresis and electron microscopy....... Binding of these proteins to SAP was demonstrated when SAP was immobilized using F(ab')2 anti-SAP, but not when SAP reacted with these proteins in liquid phase; thus the binding to human SAP was markedly phase state dependent. Presaturation of solid phase SAP with heparin, which binds SAP with high...... affinity, did not interfere with the subsequent binding of C4bp or C1q to SAP. In contrast, collagen I and IV showed partial competition with the binding of C1q to SAP. Using fresh serum, immobilized native SAP bound C4bp whereas binding of C1q/C1 could not be demonstrated. Altogether the results indicate...

  5. Errors in the SAP reference model

    NARCIS (Netherlands)

    Mendling, J.; Aalst, van der W.M.P.; Dongen, van B.F.; Verbeek, H.M.W.

    2006-01-01

    The SAP Reference Model is a set of information models that is utilized to guide the configuration of SAP systems. A big part of these models are business process models represented in the Eventdriven Process Chains (EPC) notation. These EPC models provide a easy to comprehend overview of SAP

  6. Electronic Resource Management and Design

    Science.gov (United States)

    Abrams, Kimberly R.

    2015-01-01

    We have now reached a tipping point at which electronic resources comprise more than half of academic library budgets. Because of the increasing work associated with the ever-increasing number of e-resources, there is a trend to distribute work throughout the library even in the presence of an electronic resources department. In 2013, the author…

  7. 21 CFR 133.186 - Sap sago cheese.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Sap sago cheese. 133.186 Section 133.186 Food and... Products § 133.186 Sap sago cheese. (a) Description. (1) Sap sago cheese is the food prepared by the... method described in § 133.5. Sap sago cheese is not less than 5 months old. (2) One or more of the dairy...

  8. SAP HANA cookbook

    CERN Document Server

    Chandrasekhar

    2013-01-01

    An easy-to-understand guide, covering topics using practical scenarios and live examples, and answering all possible questions.If you are a solution architect, developer, modeler, sales leader, business transformation managers, directors, COO, or CIO; this book is perfect for you.If you are interested in other technologies and want to jump-start into SAP, this book gives you the chance to learn SAP HANA. Basic knowledge of RDBMS concepts enough is to get you started.

  9. 49 CFR 40.295 - May employees or employers seek a second SAP evaluation if they disagree with the first SAP's...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false May employees or employers seek a second SAP evaluation if they disagree with the first SAP's recommendations? 40.295 Section 40.295 Transportation Office... seek a second SAP evaluation if they disagree with the first SAP's recommendations? (a) As an employee...

  10. The efficiency of mechanisms driving Subauroral Polarization Streams (SAPS

    Directory of Open Access Journals (Sweden)

    H. Wang

    2011-07-01

    Full Text Available We have investigated the seasonal and diurnal variation of SAPS (Subauroral Polarization Streams occurrence based on 3663 SAPS events identified in DMSP ion drift observations in the Northern Hemisphere during July 2001 and June 2003. Their relationships with high latitude convection electric field, substorm, and ionospheric conductivity have been addressed. SAPS occurrences show a clear seasonal and diurnal variation with the occurrence rates varying by a factor of 5. It is found that the convection electric field might play a dominant role in association with SAPS occurrence. Peak convection electric fields mark the occurrence maximum of SAPS. Substorm might play a secondary role related to SAPS occurrence. It account for the secondary maximum in SAPS occurrence rate during December solstice. Our work demonstrates that the substorm induced electric field can develop SAPS during relatively low global convection. Somewhat low fluxtube-integrated conductivity is favorable for SAPS to develop. Another topic is the temporal relationship between SAPS and substorm phases. SAPS can occur at substorm onset, substorm expansion and recovery phases. Most probably SAPS tend to occur 60 min/45 min after substorm onset during quiet/more disturbed geomagnetic activity, respectively. This indicates that enhanced global convection helps SAPS to develop quicker during substorms. The peak plasma velocity of SAPS is increased on average only by 5–10 % by the substorm process.

  11. Sap flow measurements combining sap-flux density radial profiles with punctual sap-flux density measurements in oak trees (Quercus ilex and Quercus pyrenaica) - water-use implications in a water-limited savanna-

    Science.gov (United States)

    Reyes, J. Leonardo; Lubczynski1, Maciek W.

    2010-05-01

    Sap flow measurement is a key aspect for understanding how plants use water and their impacts on the ecosystems. A variety of sensors have been developed to measure sap flow, each one with its unique characteristics. When the aim of a research is to have accurate tree water use calculations, with high temporal and spatial resolution (i.e. scaled), a sensor with high accuracy, high measurement efficiency, low signal-to-noise ratio and low price is ideal, but such has not been developed yet. Granier's thermal dissipation probes (TDP) have been widely used in many studies and various environmental conditions because of its simplicity, reliability, efficiency and low cost. However, it has two major flaws when is used in semi-arid environments and broad-stem tree species: it is often affected by high natural thermal gradients (NTG), which distorts the measurements, and it cannot measure the radial variability of sap-flux density in trees with sapwood thicker than two centimeters. The new, multi point heat field deformation sensor (HFD) is theoretically not affected by NTG, and it can measure the radial variability of the sap flow at different depths. However, its high cost is a serious limitation when simultaneous measurements are required in several trees (e.g. catchment-scale studies). The underlying challenge is to develop a monitoring schema in which HFD and TDP are combined to satisfy the needs of measurement efficiency and accuracy in water accounting. To assess the level of agreement between TDP and HFD methods in quantifying sap flow rates and temporal patterns on Quercus ilex (Q.i ) and Quercus pyrenaica trees (Q.p.), three measurement schemas: standard TDP, TDP-NTG-corrected and HFD were compared in dry season at the semi-arid Sardon area, near Salamanca in Spain in the period from June to September 2009. To correct TDP measurements with regard to radial sap flow variability, a radial sap flux density correction factor was applied and tested by adjusting TDP

  12. Sapflow+: a four-needle heat-pulse sap flow sensor enabling nonempirical sap flux density and water content measurements.

    Science.gov (United States)

    Vandegehuchte, Maurits W; Steppe, Kathy

    2012-10-01

    • To our knowledge, to date, no nonempirical method exists to measure reverse, low or high sap flux density. Moreover, existing sap flow methods require destructive wood core measurements to determine sapwood water content, necessary to convert heat velocity to sap flux density, not only damaging the tree, but also neglecting seasonal variability in sapwood water content. • Here, we present a nonempirical heat-pulse-based method and coupled sensor which measure temperature changes around a linear heater in both axial and tangential directions after application of a heat pulse. By fitting the correct heat conduction-convection equation to the measured temperature profiles, the heat velocity and water content of the sapwood can be determined. • An identifiability analysis and validation tests on artificial and real stem segments of European beech (Fagus sylvatica L.) confirm the applicability of the method, leading to accurate determinations of heat velocity, water content and hence sap flux density. • The proposed method enables sap flux density measurements to be made across the entire natural occurring sap flux density range of woody plants. Moreover, the water content during low flows can be determined accurately, enabling a correct conversion from heat velocity to sap flux density without destructive core measurements. © 2012 The Authors. New Phytologist © 2012 New Phytologist Trust.

  13. Development and psychometric evaluation of the self-assessment of psoriasis symptoms (SAPS) - clinical trial and the SAPS - real world patient-reported outcomes.

    Science.gov (United States)

    Armstrong, April W; Banderas, Benjamin; Foley, Catherine; Stokes, Jonathan; Sundaram, Murali; Shields, Alan L

    2017-09-01

    The Self-Assessment of Psoriasis Symptoms - Clinical Trials (SAPS-CT) and SAPS - Real World (SAPS-RW) were simultaneously created to assess the experience of plaque psoriasis in two unique contexts. Qualitative and quantitative research was conducted in four phases namely concept elicitation, questionnaire construction, content evaluation and psychometric evaluation. Following concept elicitation, 18 concepts were selected to inform questionnaire construction of the SAPS-CT and SAPS-RW. To accommodate each context of use, the SAPS-CT asks respondents to rate the target symptom 'at its worst' in the 24 h prior to assessment, while the SAPS-RW asks respondents to rate the target symptom "on average" in the 7 days prior to assessment. Cognitive debriefing confirmed that patients could comprehend and provide meaningful responses to both versions and, after minor modifications, resulted in 11-item questionnaires administered in an observational study (N = 200). Results from the observational study informed further item reduction (SAPS-RW to six items and SAPS-CT to nine items) and demonstrated that scores from each were reliable (Cronbach's α > 0.90, test-retest intraclass correlation coefficient >0.70), construct valid and able to differentiate among clinically distinct groups. The SAPS-CT and SAPS-RW are content-valid PRO questionnaires capable of producing psychometrically sound scores when administered chronic to plaque psoriasis patients.

  14. Ethanol and lactic acid production using sap squeezed from old oil palm trunks felled for replanting.

    Science.gov (United States)

    Kosugi, Akihiko; Tanaka, Ryohei; Magara, Kengo; Murata, Yoshinori; Arai, Takamitsu; Sulaiman, Othman; Hashim, Rokiah; Hamid, Zubaidah Aimi Abdul; Yahya, Mohd Khairul Azri; Yusof, Mohd Nor Mohd; Ibrahim, Wan Asma; Mori, Yutaka

    2010-09-01

    Old oil palm trunks that had been felled for replanting were found to contain large quantities of high glucose content sap. Notably, the sap in the inner part of the trunk accounted for more than 80% of the whole trunk weight. The glucose concentration of the sap from the inner part was 85.2g/L and decreased towards the outer part. Other sugars found in relatively low concentrations were sucrose, fructose, galactose, xylose, and rhamnose. In addition, oil palm sap was found to be rich in various kinds of amino acids, organic acids, minerals and vitamins. Based on these findings, we fermented the sap to produce ethanol using the sake brewing yeast strain, Saccharomyces cerevisiae Kyokai no.7. Ethanol was produced from the sap without the addition of nutrients, at a comparable rate and yield to the reference fermentation on YPD medium with glucose as a carbon source. Likewise, we produced lactic acid, a promising material for bio-plastics, poly-lactate, from the sap using the homolactic acid bacterium Lactobacillus lactis ATCC19435. We confirmed that sugars contained in the sap were readily converted to lactic acid with almost the same efficiency as the reference fermentation on MSR medium with glucose as a substrate. These results indicate that oil palm trunks felled for replanting are a significant resource for the production of fuel ethanol and lactic acid in palm oil-producing countries such as Malaysia and Indonesia. Copyright 2010 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  15. Behavior and Characteristics of Sap-Feeding North Island kākā (Nestor meridionalis septentrionalis) in Wellington, New Zealand.

    Science.gov (United States)

    Charles, Kerry E; Linklater, Wayne L

    2013-08-16

    The North Island kākā (Nestor meridionalis septentrionalis), a threatened New Zealand native parrot, was successfully reintroduced to an urban sanctuary in Wellington, New Zealand. Conflict has recently begun to emerge with Wellington City residents due to tree damage caused by kākā sap foraging. Little is known about sap foraging behavior of kākā, and this study aimed to gain a greater understanding of this behavior, and to test hypotheses that sap feeding is predominantly a female activity and that one technique, forming transverse gouges through bark, may be restricted to adult kākā. We used instantaneous scan sampling to record the behavior of kākā during 25 60-100 minute observation periods at Anderson Park, Wellington Botanic Garden, and during 13 opportunistic observations of sap feeding kākā in Wellington City. Forty-one observations of sap feeding were made of 21 individually-identified birds. Sap feeding birds were predominantly young and, based on estimated sex, females were no more likely to sap feed than males (exact binomial test p = 0.868). Twenty of the 21 identified sap feeding kākā utilized supplementary feeding stations at Zealandia-Karori Wildlife Sanctuary. Kākā were observed defending sap feeding sites from tui (Prosthemadera novaeseelandiae) and conspecifics. Sap appears to be an important resource for kākā across sexes and life stages, and provision of supplementary food is unlikely to reduce sap feeding and tree damage in Wellington City.

  16. SAP SE: Autism at Work

    DEFF Research Database (Denmark)

    Pisano, Gary P.; Austin, Robert D.

    2016-01-01

    This case describes SAP's 'Autism at Work' program, which integrates people with autism into the company's workforce. The company has a stated objective of making 1% o its workforce people with autism by 2020. SAP's rationale for the program is based on the belief that 'neurodiversity' contributes...

  17. [Rainfall effects on the sap flow of Hedysarum scoparium.

    Science.gov (United States)

    Yang, Qiang; Zha, Than Shan; Jia, Xin; Qin, Shu Gao; Qian, Duo; Guo, Xiao Nan; Chen, Guo Peng

    2016-03-01

    In arid and semi-arid areas, plant physiological responses to water availability depend largely on the intensity and frequency of rain events. Knowledge on the responses of xerophytic plants to rain events is important for predicting the structure and functioning of dryland ecosystems under changing climate. The sap flow of Hedysarum scoparium in the Mu Us Sand Land was continuously measured during the growing season of 2012 and 2013. The objectives were to quantify the dynamics of sap flow under different weather conditions, and to examine the responses of sap flow to rain events of different sizes. The results showed that the daily sap flow rates of H. scoparium were lower on rainy days than on clear days. On clear days, the sap flow of H. scoparium showed a midday plateau, and was positively correlated with solar radiation and relative humidity. On rainy days, the sap flow fluctuated at low levels, and was positively correlated with solar radiation and air temperature. Rain events not only affected the sap flow on rainy days through variations in climatic factors (e.g., solar radiation and air temperature), but also affected post-rainfall sap flow velocities though changes in soil moisture. Small rain events (sap flow, whereas large rain events (>20 mm) significantly increased the sap flow on days following rainfall. Rain-wetted soil conditions not only resulted in higher sap flow velocities, but also enhanced the sensitivity of sap flow to solar radiation, vapor pressure deficit and air temperature.

  18. Comparative analysis of the ternary complex factors Elk-1, SAP-1a and SAP-2 (ERP/NET).

    Science.gov (United States)

    Price, M A; Rogers, A E; Treisman, R

    1995-06-01

    A transcription factor ternary complex composed of Serum Response Factor (SRF) and Ternary Complex Factor (TCF) mediates the response of the c-fos Serum Response Element (SRE) to growth factors and mitogens. Three Ets domain proteins, Elk-1, SAP-1 and ERP/NET, have been reported to have the properties of TCF. Here we compare Elk-1 and SAP-1a with the human ERP/NET homologue SAP-2. All three TCF RNAs are ubiquitously expressed at similar relative levels. All three proteins contain conserved regions that interact with SRF and the c-fos SRE with comparable efficiency, but in vitro complex formation by SAP-2 is strongly inhibited by its C-terminal sequences. Similarly, only Elk-1 and SAP-1a efficiently bind the c-fos SRE in vivo; ternary complex formation by SAP-2 is weak and is substantially unaffected by serum stimulation or v-ras co-expression. All three TCFs contain C-terminal transcriptional activation domains that are phosphorylated following growth factor stimulation. Activation requires conserved S/T-P motifs found in all the TCF family members. Each TCF activation domain can be phosphorylated in vitro by partially purified ERK2, and ERK activation in vivo is sufficient to potentiate transcriptional activation.

  19. SAPS simulation with GITM/UCLA-RCM coupled model

    Science.gov (United States)

    Lu, Y.; Deng, Y.; Guo, J.; Zhang, D.; Wang, C. P.; Sheng, C.

    2017-12-01

    Abstract: SAPS simulation with GITM/UCLA-RCM coupled model Author: Yang Lu, Yue Deng, Jiapeng Guo, Donghe Zhang, Chih-Ping Wang, Cheng Sheng Ion velocity in the Sub Aurora region observed by Satellites in storm time often shows a significant westward component. The high speed westward stream is distinguished with convection pattern. These kind of events are called Sub Aurora Polarization Stream (SAPS). In March 17th 2013 storm, DMSP F18 satellite observed several SAPS cases when crossing Sub Aurora region. In this study, Global Ionosphere Thermosphere Model (GITM) has been coupled to UCLA-RCM model to simulate the impact of SAPS during March 2013 event on the ionosphere/thermosphere. The particle precipitation and electric field from RCM has been used to drive GITM. The conductance calculated from GITM has feedback to RCM to make the coupling to be self-consistent. The comparison of GITM simulations with different SAPS specifications will be conducted. The neutral wind from simulation will be compared with GOCE satellite. The comparison between runs with SAPS and without SAPS will separate the effect of SAPS from others and illustrate the impact on the TIDS/TADS propagating to both poleward and equatorward directions.

  20. Application of Super Absorbent Polymers (SAP) in Concrete Construction State-of-the-Art Report Prepared by Technical Committee 225-SAP

    CERN Document Server

    Reinhardt, Hans-Wolf

    2012-01-01

    This is the state-of-the-art report prepared by the RILEM TC “Application of Super Absorbent Polymers (SAP) in concrete construction”. It gives a comprehensive overview of the properties of SAP, specific water absorption and desorption behaviour of SAP in fresh and hardening concrete, effects of the SAP addition on rheological properties of fresh concrete, changes of cement paste microstructure and mechanical properties of concrete. Furthermore, the key advantages of using SAP are described in detail: the ability of this material to act as an internal curing agent to mitigate autogenous shrinkage of high-performance concrete, the possibility to use SAP as an alternative to air-entrainment agents in order to increase the frost resistance of concrete, and finally, the benefit of steering the rheology of fresh cement-based materials. The final chapter describes the first existing and numerous prospective applications for this new concrete additive.

  1. Experimental Assessment of the Use of a Novel Superabsorbent polymer (SAP for the Optimization ofWater Consumption in Agricultural Irrigation Process

    Directory of Open Access Journals (Sweden)

    Giuseppe Cannazza

    2014-07-01

    Full Text Available In this work, an innovative cellulose-based superabsorbent polymer (SAP was experimentally assessed as an environmentally friendly alternative to acrylate-based SAPs, for the optimization of water consumption in agriculture. The cellulose-based SAP was synthesized and tested for its swelling capability in different aqueous media. The effectiveness of the SAP in agricultural applications was then evaluated by analyzing its performance after several absorption/desorption cycles, over a period of approximately 80 days, upon addition to different types of soil, i.e., white and red soil, for the cultivation of two varieties of plants typical of the Mediterranean area (tomatoes and chicory. The results confirmed that SAP-amended soil can store a considerable amount of water and can release it gradually to the plant roots when needed. The adoption of the proposed SAP in cultivations could thus represent a promising solution for the rationalization of water resources, especially in desert areas.

  2. 46 CFR 16.203 - Employer, MRO, and SAP responsibilities.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 1 2010-10-01 2010-10-01 false Employer, MRO, and SAP responsibilities. 16.203 Section... CHEMICAL TESTING Required Chemical Testing § 16.203 Employer, MRO, and SAP responsibilities. (a) Employers...) Substance Abuse Professional (SAP). Individuals performing SAP functions must meet the training requirements...

  3. Field Note: Threatening Tonle Sap: Challenges for Southeast-Asia’s largest Freshwater Lake

    Directory of Open Access Journals (Sweden)

    Kuenzer, Claudia

    2013-09-01

    Full Text Available The Tonle Sap ecosystem in Cambodia is Southeast Asia’s largest freshwater lake; strongly impacted by the Mekong river flood pulse. The lake is home to exceptional biodiversity, and rural communities living in free floating villages on the lake and on its shores. The fragile niche ecosystems as well as the rural livelihoods of Tonle Sap are under severe threat. Overfishing, illegal wood harvesting, further resource exploitation, and water quality deterioration all impact the stability of the socio-ecological system of Tonle Sap. At the same time, expected flood pulse changes due to regulatory measures in the context of hydropower development upstream on the Mekong are a severe threat for Tonle Sap’s ecosystem stability. The area needs to shift into the focus of attention of national and international re-searchers, stakeholders, and decision makers, to find suitable pathways for a future sustainable development of this unique and pristine region.

  4. Thermal-dissipation sap flow sensors may not yield consistent sap-flux estimates over multiple years

    Science.gov (United States)

    Georgianne W. Moore; Barbara J. Bond; Julia A. Jones; Frederick C. Meinzer

    2010-01-01

    Sap flow techniques, such as thermal dissipation, involve an empirically derived relationship between sap flux and the temperature differential between a heated thermocouple and a nearby reference thermocouple inserted into the sapwood. This relationship has been widely tested but mostly with newly installed sensors. Increasingly, sensors are used for extended periods...

  5. Assessing Leading ERP-SAP Implementation in Leading Firms in Indonesia

    Science.gov (United States)

    Syaiful, B.; Gunawan, W.

    2017-01-01

    Enterprise resource planning (ERP) enables to bring critical capabilities to an organisation, however, the implementation of such capabilities is often surrounded with problems. The implementing ERP-SAP in Indonesian enterprises are still facing tremendous challenges with the failure rate can reach more than 80% of the cases. The article examines the common problems faced by the consultants whenever they deal with their clients, from the practical perspectives. The article takes the multiple case studies of the leading enterprises in Indonesia, such as: KS (largest steel producer), GEM (large mining producer), and HS (large retailer), with the aim to identify the root of problems of SAP implementation. The outcome of the study is expected to provide the consultants with the guideline to understand the ERP implementation process in their clients and effective solutions to cope with it.

  6. Auditing and GRC automation in SAP

    CERN Document Server

    Chuprunov, Maxim

    2013-01-01

    Going beyond current literature, this book extends internal controls to efficiency and profitability. Offers an audit guide for an SAP ERP system, covers risks and control descriptions, and shows how to automate compliance management based on SAP GRC.

  7. 49 CFR 655.52 - Substance abuse professional (SAP).

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Substance abuse professional (SAP). 655.52 Section 655.52 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL TRANSIT... OPERATIONS Drug and Alcohol Testing Procedures § 655.52 Substance abuse professional (SAP). The SAP must...

  8. 30 CFR 285.617 - What activities require a revision to my SAP, and when will MMS approve the revision?

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities require a revision to my SAP, and when will MMS approve the revision? 285.617 Section 285.617 Mineral Resources MINERALS MANAGEMENT...: (1) Designed not to cause undue harm or damage to natural resources; life (including human and...

  9. Faculty perceptions of the integration of SAP in academic programs

    Directory of Open Access Journals (Sweden)

    Sam Khoury

    2012-08-01

    Full Text Available In order to prepare students for the workforce, academic programs incorporate a variety of tools that students are likely to use in their future careers. One of these tools employed by business and technology programs is the integration of live software applications such as SAP through the SAP University Alliance (SAP UA program. Since the SAP UA program has been around for only about 10 years and the available literature on the topic is limited, research is needed to determine the strengths and weaknesses of the SAP UA program. A collaborative study of SAP UA faculty perceptions of their SAP UAs was conducted in the fall of 2011. Of the faculty invited to participate in the study, 31% completed the online survey. The results indicate that most faculty experienced difficulty implementing SAP into their programs and report that a need exists for more standardized curriculum and training, while a large percentage indicated that they are receiving the support they need from their schools and SAP.

  10. SAP deficiency mitigated atherosclerotic lesions in ApoE(-/-) mice.

    Science.gov (United States)

    Zheng, Lingyun; Wu, Teng; Zeng, Cuiling; Li, Xiangli; Li, Xiaoqiang; Wen, Dingwen; Ji, Tianxing; Lan, Tian; Xing, Liying; Li, Jiangchao; He, Xiaodong; Wang, Lijing

    2016-01-01

    Serum amyloid P conpoent (SAP), a member of the pentraxin family, interact with pathogens and cell debris to promote their removal by macrophages and neutrophils and is co-localized with atherosclerotic plaques in patients. However, the exact mechanism of SAP in atherogenesis is still unclear. We investigated whether SAP influence macrophage recruitment and foam cell formation and ultimately affect atherosclerotic progression. we generated apoE(-/-); SAP(-/-) (DKO) mice and fed them western diet for 4 and 8 weeks to characterize atherosclerosis development. SAP deficiency effectively reduced plaque size both in the aorta (p = 0.0006 for 4 wks; p = 0.0001 for 8 wks) and the aortic root (p = 0.0061 for 4 wks; p = 0.0079 for 8wks) compared with apoE(-/-) mice. Meanwhile, SAP deficiency inhibited oxLDL-induced foam cell formation (p = 0.0004) compared with apoE(-/-) mice and SAP treatment increases oxLDL-induced foam cell formation (p = 0.002) in RAW cells. Besides, SAP deficiency reduced macrophages recruitment (p = 0.035) in vivo and in vitro (p = 0.026). Furthermore, SAP treatment enhanced CD36 (p = 0.007) and FcγRI (p = 0.031) expression induced by oxLDL through upregulating JNK and p38 MAPK phosphorylation whereas specific JNK1/2 inhibitor reduced CD36 (p = 0.0005) and FcγRI (P = 0.0007) expression in RAW cell. SAP deficiency also significantly decreased the expression of M1 and M2 macrophage markers and inflammatory cytokines in oxLDL-induced macrophages. SAP deficiency mitigated foam cell formation and atherosclerotic development in apoE(-/-) mice, due to reduction in macrophages recruitment, polarization and pro-inflammatory cytokines and inhibition the CD36/FcγR-dependent signaling pathway. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  11. Implementação de sistemas SAP em empresas de serviços públicos

    OpenAIRE

    Gonçalves, Elisabete Gabriela de Oliveira

    2012-01-01

    Dissertação de mestrado em Engenharia e Gestão de Sistemas A utilização de sistemas Enterprise Resource Planning (ERP) para organizar a informação relevante de uma organização é cada vez mais frequente. Com este documento pretende-se explorar o percurso profissional na implementação de sistemas ERP, mais precisamente na implementação de sistemas SAP para empresas de serviços públicos, ou seja implementação de sistemas SAP IS-U. Apesar do foco principal do presente documento ...

  12. Architecture of SAP ERP understand how successful software works

    CERN Document Server

    Boeder, Jochen

    2014-01-01

    This book - compiled by software architects from SAP - is a must for consultants, developers, IT managers, and students working with SAP ERP, but also users who want to know the world behind their SAP user interface.

  13. Water relations in silver birch during springtime: How is sap pressurised?

    Science.gov (United States)

    Hölttä, T; Dominguez Carrasco, M D R; Salmon, Y; Aalto, J; Vanhatalo, A; Bäck, J; Lintunen, A

    2018-05-06

    Positive sap pressures are produced in the xylem of birch trees in boreal conditions during the time between the thawing of the soil and bud break. During this period, xylem embolisms accumulated during wintertime are refilled with water. The mechanism for xylem sap pressurization and its environmental drivers are not well known. We measured xylem sap flow, xylem sap pressure, xylem sap osmotic concentration, xylem and whole stem diameter changes, and stem and root non-structural carbohydrate concentrations, along with meteorological conditions at two sites in Finland during and after the sap pressurisation period. The diurnal dynamics of xylem sap pressure and sap flow during the sap pressurisation period varied, but were more often opposite to the diurnal pattern after bud burst, i.e. sap pressure increased and sap flow rate mostly decreased when temperature increased. Net conversion of soluble sugars to starch in the stem and roots occurred during the sap pressurisation period. Xylem sap osmotic pressure was small in comparison to total sap pressure, and it did not follow changes in environmental conditions or tree water relations. Based on these findings, we suggest that xylem sap pressurisation and embolism refilling occur gradually over a few weeks through water transfer from parenchyma cells to xylem vessels during daytime, and then the parenchyma are refilled mostly during nighttime by water uptake from soil. Possible drivers for water transfer from parenchyma cells to vessels are discussed. Also the functioning of thermal dissipation probes in conditions of changing stem water content is discussed. © 2018 German Society for Plant Sciences and The Royal Botanical Society of the Netherlands.

  14. Electronic Resource Management Systems

    Directory of Open Access Journals (Sweden)

    Mark Ellingsen

    2004-10-01

    Full Text Available Computer applications which deal with electronic resource management (ERM are quite a recent development. They have grown out of the need to manage the burgeoning number of electronic resources particularly electronic journals. Typically, in the early years of e-journal acquisition, library staff provided an easy means of accessing these journals by providing an alphabetical list on a web page. Some went as far as categorising the e-journals by subject and then grouping the journals either on a single web page or by using multiple pages. It didn't take long before it was recognised that it would be more efficient to dynamically generate the pages from a database rather than to continually edit the pages manually. Of course, once the descriptive metadata for an electronic journal was held within a database the next logical step was to provide administrative forms whereby that metadata could be manipulated. This in turn led to demands for incorporating more information and more functionality into the developing application.

  15. Antidiarrhoeal Activity of Musa paradisiaca Sap in Wistar Rats.

    Science.gov (United States)

    Yakubu, Musa T; Nurudeen, Quadri O; Salimon, Saoban S; Yakubu, Monsurat O; Jimoh, Rukayat O; Nafiu, Mikhail O; Akanji, Musbau A; Oladiji, Adenike T; Williams, Felicia E

    2015-01-01

    The folkloric claim of Musa paradisiaca sap in the management of diarrhoea is yet to be substantiated or refuted with scientific data. Therefore, the aim of the current study was to screen the sap of M. paradisiaca for both its secondary metabolites and antidiarrhoeal activity at 0.25, 0.50, and 1.00 mL in rats. Secondary metabolites were screened using standard methods while the antidiarrhoeal activity was done by adopting the castor oil-induced diarrhoeal, castor oil-induced enteropooling, and gastrointestinal motility models. The sap contained flavonoids, phenolics, saponins, alkaloids, tannins, and steroids while cardiac glycosides, anthraquinones, triterpenes, cardenolides, and dienolides were not detected. In the castor oil-induced diarrhoeal model, the sap significantly (P sap were accompanied by increase in inhibition of intestinal fluid content in the enteropooling model. The sap decreased the charcoal meal transit in the gastrointestinal motility model. In all the models, the 1.00 mL of the sap produced changes that compared well with the reference drugs. Overall, the antidiarrhoeal activity of Musa paradisiaca sap attributed to the presence of alkaloids, phenolics, flavonoids, and/or saponins which may involve, among others, enhancing fluid and electrolyte absorption through de novo synthesis of the sodium potassium ATPase and/or reduced nitric oxide levels.

  16. 49 CFR 40.311 - What are the requirements concerning SAP reports?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What are the requirements concerning SAP reports... Process § 40.311 What are the requirements concerning SAP reports? (a) As the SAP conducting the required... ensure that you receive SAP written reports directly from the SAP performing the evaluation and that no...

  17. Physicochemical changes of raffia sap (Raphia mambillensis ...

    African Journals Online (AJOL)

    galax-07

    2013-10-09

    Oct 9, 2013 ... on fermentation on the raffia sap property, its physico-chemical and .... transformed organic nitrogen of the dried sap into mineral nitrogen ..... International Congress on Engineering and Food. March ... uses in vignification.

  18. Validation of the scale on Satisfaction of Adolescents with Postoperative pain management-idiopathic Scoliosis (SAP-S

    Directory of Open Access Journals (Sweden)

    Khadra C

    2017-01-01

    Full Text Available Christelle Khadra,1–3 Sylvie Le May,1,2 Ariane Ballard,1,2 Jean Théroux,1,4 Sylvie Charette,5 Edith Villeneuve,6,7 Stefan Parent,2,8,9 Argerie Tsimicalis,10,11 Jill MacLaren Chorney12,13 1Faculty of Nursing, Université de Montréal, 2CHU Sainte-Justine Research Centre, 3Montreal Chest Institute, McGill University Health Centre, Montreal, QC, Canada; 4School of Health Professions, Murdoch University, Perth, WA, Australia; 5Direction of Nursing, 6Department of Anesthesia, CHU Sainte-Justine, 7Department of Anesthesia, 8Department of Surgery, Faculty of Medicine, Université de Montréal, 9Orthopaedic Service, Department of Surgery, CHU Sainte-Justine, 10Ingram School of Nursing, McGill University, 11Shriners Hospitals for Children, Montreal, QC, 12Pediatric Complex Pain Team, IWK Health Centre, 13Department of Anesthesia, Pain Management, and Perioperative Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada Background: Spinal fusion is a common orthopedic surgery in children and adolescents and is associated with high pain levels postoperatively. If the pain is not well managed, negative outcomes may ensue. To our knowledge, there is no measure in English that assesses patient’s satisfaction with postoperative pain management following idiopathic scoliosis surgery. The aim of the present study was to assess the psychometric properties of the satisfaction subscale of the English version of the Satisfaction of Adolescents with Postoperative pain management – idiopathic Scoliosis (SAP-S scale.Methods: Eighty-two participants aged 10–18 years, who had undergone spinal fusion surgery, fully completed the SAP-S scale at 10–14 days postdischarge. Construct validity was assessed through a principal component analysis using varimax rotation.Results: Principal component analysis indicated a three-factor structure of the 13-item satisfaction subscale of the SAP-S scale. Factors referred to satisfaction regarding current

  19. Electronic Resources Management Project Presentation 2012

    KAUST Repository

    Ramli, Rindra M.

    2012-11-05

    This presentation describes the electronic resources management project undertaken by the KAUST library. The objectives of this project is to migrate information from MS Sharepoint to Millennium ERM module. One of the advantages of this migration is to consolidate all electronic resources into a single and centralized location. This would allow for better information sharing among library staff.

  20. Ada Apa Dengan SAP (AADS Akrual?

    Directory of Open Access Journals (Sweden)

    Eka Findi Tresnawati

    2013-08-01

    Full Text Available This article provides anoverview regarding SAP accrual-based and its problems. It compares information content of PP 24/2005’s cash toward accrual and PP 71/2010’s accrual-based toshow the urgency of accrual-based financial reporting requirements. The analysis borrows Abeysekara’s accounting imperialism. Discussion also involves empirical evidence and evaluation of accrual-based implementation probability in Sumenep Regency. Findings show that accrual-based information is not an urgent need and tends to be difficult to be implemented. Reflecting the evidence in Sumenep, local governments are faced with the need of human resources, the question of the use-fulness of accrual information, and technical difficulties on implementation.

  1. SAP: structure, function, and its roles in immune-related diseases.

    Science.gov (United States)

    Xi, Dan; Luo, TianTian; Xiong, Haowei; Liu, Jichen; Lu, Hao; Li, Menghao; Hou, Yuqing; Guo, Zhigang

    2015-01-01

    Serum amyloid P component (SAP), also known as pentraxin-2, is a member of the pentraxin protein family with an established relationship to the immune response. In the last century, SAP has been used as a diagnostic marker in amyloidosis diagnosis and patient follow-up. SAP has been thought to have potential for treating and curing amyloidosis and fibrosis diseases. More recently, it has been shown that SAP may serve as both a diagnostic marker and a therapeutic target for many immune-related diseases, such as cardiovascular, pulmonary, nephritic, neurological and autoimmune diseases. In the cardiovascular system, SAP has been defined as the culprit in amyloidosis in the heart. SAP may also exert a protective role during the early stage of atherosclerosis and myocardial fibrosis. In noncardiovascular system diseases, SAP is being developed for the treatment of pulmonary fibrosis. In this review, we summarize SAP history, structure, and its roles in immune-related diseases in different systems with emphasis on the cardiovascular system. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  2. Pigmentiphaga aceris sp. nov., isolated from tree sap.

    Science.gov (United States)

    Lee, Soon Dong

    2017-09-01

    Two Gram-stain-negative bacterial strains, SAP-32T and SAP-36, were isolated from sap drawn from the Acer pictum from Mount Halla in Jeju, Republic of Korea. The organisms were strictly aerobic, non-sporulating, motile rods and showed growth at 10-30 °C, pH 7-8 and with 0-2 % NaCl. The major isoprenoid quinone was Q-8. The predominant fatty acids were C16 : 0, cyclo-C17 : 0, summed feature 3 and C18 : 0. The polar lipids contained phosphatidylcholine, phosphatidylethanolamine, phosphatidylglycerol, an unknown aminophosphoglycolipid, an unknown glycolipid, an unknown phospholipid and two unknown lipids. The DNA G+C content was 64.4 mol%. The results of phylogenetic analyses based on 16S rRNA gene sequences indicated that SAP-32T and SAP-36 formed a distinct cluster with members of the genus Pigmentiphaga within the family Alcaligenaceae. Both strains showed 16S rRNA gene sequence similarity of 100 % to each other. The closest relatives of the isolates were Pigmentiphaga daeguensis (97.08 % sequence similarity), Pigmentiphaga kullae (97.01 %) and Pigmentiphaga litoralis (96.73 %). On the basis of data from phenotypic, chemotaxonomic and phylogenetic analyses, SAP-32T (=KCTC 52619T=DSM 104039T) and SAP-36 (=KCTC 52620=DSM 104072) represent members of a novel species of the genus Pigmentiphaga, for which the name Pigmentiphaga aceris sp. nov. is proposed.

  3. SAP modulates B cell functions in a genetic background-dependent manner.

    Science.gov (United States)

    Detre, Cynthia; Yigit, Burcu; Keszei, Marton; Castro, Wilson; Magelky, Erica M; Terhorst, Cox

    2013-06-01

    Mutations affecting the SLAM-associated protein (SAP) are responsible for the X-linked lympho-proliferative syndrome (XLP), a severe primary immunodeficiency syndrome with disease manifestations that include fatal mononucleosis, B cell lymphoma and dysgammaglobulinemia. It is well accepted that insufficient help by SAP-/- CD4+ T cells, in particular during the germinal center reaction, is a component of dysgammaglobulinemia in XLP patients and SAP-/- animals. It is however not well understood whether in XLP patients and SAP-/- mice B cell functions are affected, even though B cells themselves do not express SAP. Here we report that B cell intrinsic responses to haptenated protein antigens are impaired in SAP-/- mice and in Rag-/- mice into which B cells derived from SAP-/- mice together with wt CD4+ T cells had been transferred. This impaired B cells functions are in part depending on the genetic background of the SAP-/- mouse, which affects B cell homeostasis. Surprisingly, stimulation with an agonistic anti-CD40 causes strong in vivo and in vitro B cell responses in SAP-/- mice. Taken together, the data demonstrate that genetic factors play an important role in the SAP-related B cell functions. The finding that anti-CD40 can in part restore impaired B cell responses in SAP-/- mice, suggests potentially novel therapeutic interventions in subsets of XLP patients. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. PRINCIPLES OF CONTENT FORMATION EDUCATIONAL ELECTRONIC RESOURCE

    Directory of Open Access Journals (Sweden)

    О Ю Заславская

    2017-12-01

    Full Text Available The article considers modern possibilities of information and communication technologies for the design of electronic educational resources. The conceptual basis of the open educational multimedia system is based on the modular architecture of the electronic educational resource. The content of the electronic training module can be implemented in several versions of the modules: obtaining information, practical exercises, control. The regularities in the teaching process in modern pedagogical theory are considered: general and specific, and the principles for the formation of the content of instruction at different levels are defined, based on the formulated regularities. On the basis of the analysis, the principles of the formation of the electronic educational resource are determined, taking into account the general and didactic patterns of teaching.As principles of the formation of educational material for obtaining information for the electronic educational resource, the article considers: the principle of methodological orientation, the principle of general scientific orientation, the principle of systemic nature, the principle of fundamentalization, the principle of accounting intersubject communications, the principle of minimization. The principles of the formation of the electronic training module of practical studies in the article include: the principle of systematic and dose based consistency, the principle of rational use of study time, the principle of accessibility. The principles of the formation of the module for monitoring the electronic educational resource can be: the principle of the operationalization of goals, the principle of unified identification diagnosis.

  5. American specialists and SAP project

    International Nuclear Information System (INIS)

    Andrlova, Z.

    2008-01-01

    Within the past days of November the project teams of SAP Nuclear in Slovenske elektrarne, a. s. incorporated the specialists from PSEG from New Jersey, U.S.A. The goal of their stay here was to pass on the professional experience and good practice from the implementation of quite demanding project in the nuclear power plants. We have learned more about the company and the objectives from an interview with Clay Warren, SAP Nuclear Project Manager in SE. (author)

  6. Comparisons of Simulated and Observed Sub-Auroral Polarization Stream (SAPS) during the 17 March 2013 Storm

    Science.gov (United States)

    Chen, M.; Lemon, C.; Sazykin, S. Y.; Wolf, R.; Anderson, P. C.

    2016-12-01

    Sub-Auroral Polarization Streams (SAPS), characterized by large subauroral E x B velocities that span from dusk to the early morning sector for high magnetic activity, result from strong magnetosphere-ionosphere coupling. We investigate how electron and ion precipitation and the ionospheric conductance affect the simulated development of the SAPS electric field for the 17 March 2013 storm. Our approach is to use the magnetically and electrically self-consistent Rice Convection Model - Equilibrium (RCM-E) of the inner magnetosphere to simulate the SAPS. We use parameterized rates of whistler-generated electron pitch-angle scattering from Orlova and Shprits [JGR, 2014] that depend on equatorial radial distance, magnetic activity (Kp), and magnetic local time (MLT) outside the simulated plasmasphere. Inside the plasmasphere, parameterized scattering rates due to hiss [Orlova et al., GRL, 2014] are used. Ions are scattered at a fraction of strong pitch-angle scattering where the fraction is scaled by epsilon, the ratio of the gyroradius to the field-line radius of curvature, when epsilon is greater than 0.1. The electron and proton contributions to the auroral conductance in the RCM-E are calculated using the empirical Robinson et al. [JGR, 1987] and Galand and Richmond [JGR, 2001] equations, respectively. The "background" ionospheric conductance is based on parameters from the International Reference Ionosphere [Bilitza and Reinisch, JASR, 2008] but modified to include the effect of specified ionospheric troughs. Parameterized simulations will aid in understanding the underlying physical process. We compare simulated precipitating particle energy flux and E x B velocities with DMSP observations where SAPS are observed during the 17 March 2013 storm. Analysis of discerpancies between the simulation results and data will aid us in assessing needed improvements in the model.

  7. Implementing CORAL: An Electronic Resource Management System

    Science.gov (United States)

    Whitfield, Sharon

    2011-01-01

    A 2010 electronic resource management survey conducted by Maria Collins of North Carolina State University and Jill E. Grogg of University of Alabama Libraries found that the top six electronic resources management priorities included workflow management, communications management, license management, statistics management, administrative…

  8. CT measurements of SAP voids in concrete

    DEFF Research Database (Denmark)

    Laustsen, Sara; Bentz, Dale P.; Hasholt, Marianne Tange

    2010-01-01

    X-ray computed tomography (CT) scanning is used to determine the SAP void distribution in hardened concrete. Three different approaches are used to analyse a binary data set created from CT measurement. One approach classifies a cluster of connected, empty voxels (volumetric pixel of a 3D image......) as one void, whereas the other two approaches are able to classify a cluster of connected, empty voxels as a number of individual voids. Superabsorbent polymers (SAP) have been used to incorporate air into concrete. An advantage of using SAP is that it enables control of the amount and size...... of the created air voids. The results indicate the presence of void clusters. To identify the individual voids, special computational approaches are needed. The addition of SAP results in a dominant peak in two of the three air void distributions. Based on the position (void diameter) of the peak, it is possible...

  9. Uses of tree saps in northern and eastern parts of Europe

    Directory of Open Access Journals (Sweden)

    Ingvar Svanberg

    2012-12-01

    Full Text Available In this article we review the use of tree saps in northern and eastern Europe. Published accounts by travellers, ethnologists and ethnobotanists were searched for historical and contemporary details. Field observations made by the authors have also been used. The presented data shows that the use of tree sap has occurred in most north and eastern European countries. It can be assumed that tree saps were most used where there were extensive stands of birch or maple trees, as these two genera generally produce the largest amount of sap. The taxa most commonly used have been Betula pendula, B. pubescens, and Acer platanoides, but scattered data on the use of several other taxa are presented. Tree sap was used as a fresh drink, but also as an ingredient in food and beverages. It was also fermented to make light alcoholic products like ale and wine. Other folk uses of tree saps vary from supplementary nutrition in the form of sugar, minerals and vitamins, to cosmetic applications for skin and hair and folk medicinal use. Russia, Ukraine, Belarus, Estonia, Latvia and Lithuania are the only countries where the gathering and use of sap (mainly birch sap has remained an important activity until recently, due to the existence of large birch forests, low population density and the incorporation of sap into the former Soviet economic system. It is evident that gathering sap from birch and other trees was more widespread in earlier times. There are records indicating extensive use of tree saps from Scandinavia, Poland, Slovakia and Romania, but it is primarily of a historical character. The extraction of tree sap in these countries is nowadays viewed as a curiosity carried out only by a few individuals. However, tree saps have been regaining popularity in urban settings through niche trading.

  10. Managing electronic resources a LITA guide

    CERN Document Server

    Weir, Ryan O

    2012-01-01

    Informative, useful, current, Managing Electronic Resources: A LITA Guide shows how to successfully manage time, resources, and relationships with vendors and staff to ensure personal, professional, and institutional success.

  11. SAP Nuclear Competence Centre

    International Nuclear Information System (INIS)

    Andrlova, Z.

    2009-01-01

    In this issue we continue and introduce the SAP Nuclear Competence Centre and its head Mr. Igor Dzama. SAP Nuclear Competence Centrum is one of the fi rst competence centres outside ENEL headquarters. It should operate in Slovakia and should have competencies within the whole Enel group. We are currently dealing with the issues of organisation and funding. We are trying to balance the accountability to the NPP directors and to the management of the competence centres at Enel headquarters; we are looking at the relations between the competence centres within the group and defining the services that we will provide for the NPPs. author)

  12. Stable-carbon isotopic composition of maple sap and foliage

    International Nuclear Information System (INIS)

    Leavitt, S.W.; Long, A.

    1985-01-01

    The 13 C/ 12 C ratios of Acer grandidentatum sap sugar collected during the dormant period are compared to those of buds, leaves, and wood developed over the following growing season. As the primary carbon source for cellulose manufacture at initiation of annual growth in deciduous trees, sap sucrose would be expected to have an isotopic composition similar to first-formed cellulose. Although constancy in concentration and 13 C/ 12 C ratios of the maple sap sugar suggests any gains or losses (e.g. to maintenance metabolism) do not appreciably alter composition, the 13 C/ 12 C ratios of cellulose of the enlarging buds in the spring are quite distinct from those of the sap sugar, seemingly precluding a simple direct biochemical pathway of sap sucrose→glucose→cellulose in favor of a more complex pathway with greater likelihood of isotopic fractionation. The 13 C/ 12 C ratios of the leaves and in the growth ring were initially similar to the sap sugar but decreased steadily over the growing season. (author)

  13. The installations maintenance control using SAP R/3; O controle de manutencao de instalacoes utilizando o SAP R/3

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Robison Tirre; Pereira, Paulo Manoel Borges; Jorge, Kemal Vieira [Transportadora Brasileira Gasoduto Bolivia Brasil S.A., Rio de Janeiro, RJ (Brazil)

    2004-07-01

    TBG (Transportadora Brasileira Gasoduto Bolivia Brasil S.A.) began their operations in 1999 and since the beginning the SAP R/3 PM module (Plant Maintenance) is used for the control of the maintenance activities and to manager the Master Maintenance and Inspection Plans. On these five years, a series of reports and SAP functionalities were developed or configured to adapt the system R/3 to the needs of TBG maintenance. Now, the whole management and control of the surface facilities maintenance (compression station, city gate, measurement station, etc) is accomplished by SAP R/3 system. (author)

  14. Variability of sap flow on forest hillslopes: patterns and controls

    Science.gov (United States)

    Hassler, Sibylle; Blume, Theresa

    2013-04-01

    Sap flow in trees is an essential variable in integrated studies of hydrologic fluxes. It gives indication of transpiration rates for single trees and, with a suitable method of upscaling, for whole stands. This information is relevant for hydrologic and climate models, especially for the prediction of change in water fluxes in the soil-plant-atmosphere continuum under climate change. To this end, we do not only need knowledge concerning the response of sapflow to atmospheric forcing but also an understanding of the main controls on its spatial variability. Our study site consists of several subcatchments of the Attert basin in Luxembourg underlain by schists of the Ardennes massif. Within these subcatchments we measure sap flow in more than 20 trees on a range of forested hillslopes covered by a variety of temperate deciduous tree species such as beech, oak, hornbeam and maple as well as conifers such as firs. Our sap flow sensors are based on the heat pulse velocity method and consist of three needles, one needle acting as the heating device and the other two holding three thermistors each, enabling us to simultaneously measure sap flow velocity at three different depths within the tree. In close proximity to the trees we collect additional data on soil moisture, matric potential and groundwater levels. First results show that the sensor design seems promising for an upscaling of the measured sap flow velocities to sap flow at the tree level. The maximum depth of actively used sapwood as well as the decrease in sap flow velocity with increasing depth in the tree can be determined by way of the three thermistors. Marked differences in sap flow velocity profiles are visible between the different species, resulting in differences in sap flow for trees of similar diameter. We examine the range of tree sap flow values and variation due to species, size class, slope position and exposition and finally relate them to the dynamics of soil moisture conditions with the

  15. Structural and binding studies of SAP-1 protein with heparin.

    Science.gov (United States)

    Yadav, Vikash K; Mandal, Rahul S; Puniya, Bhanwar L; Kumar, Rahul; Dey, Sharmistha; Singh, Sarman; Yadav, Savita

    2015-03-01

    SAP-1 is a low molecular weight cysteine protease inhibitor (CPI) which belongs to type-2 cystatins family. SAP-1 protein purified from human seminal plasma (HuSP) has been shown to inhibit cysteine and serine proteases and exhibit interesting biological properties, including high temperature and pH stability. Heparin is a naturally occurring glycosaminoglycan (with varied chain length) which interacts with a number of proteins and regulates multiple steps in different biological processes. As an anticoagulant, heparin enhances inhibition of thrombin by the serpin antithrombin III. Therefore, we have employed surface plasmon resonance (SPR) to improve our understanding of the binding interaction between heparin and SAP-1 (protease inhibitor). SPR data suggest that SAP-1 binds to heparin with a significant affinity (KD = 158 nm). SPR solution competition studies using heparin oligosaccharides showed that the binding of SAP-1 to heparin is dependent on chain length. Large oligosaccharides show strong binding affinity for SAP-1. Further to get insight into the structural aspect of interactions between SAP-1 and heparin, we used modelled structure of the SAP-1 and docked with heparin and heparin-derived polysaccharides. The results suggest that a positively charged residue lysine plays important role in these interactions. Such information should improve our understanding of how heparin, present in the reproductive tract, regulates cystatins activity. © 2014 John Wiley & Sons A/S.

  16. Antidiarrhoeal Activity of Musa paradisiaca Sap in Wistar Rats

    Directory of Open Access Journals (Sweden)

    Musa T. Yakubu

    2015-01-01

    Full Text Available The folkloric claim of Musa paradisiaca sap in the management of diarrhoea is yet to be substantiated or refuted with scientific data. Therefore, the aim of the current study was to screen the sap of M. paradisiaca for both its secondary metabolites and antidiarrhoeal activity at 0.25, 0.50, and 1.00 mL in rats. Secondary metabolites were screened using standard methods while the antidiarrhoeal activity was done by adopting the castor oil-induced diarrhoeal, castor oil-induced enteropooling, and gastrointestinal motility models. The sap contained flavonoids, phenolics, saponins, alkaloids, tannins, and steroids while cardiac glycosides, anthraquinones, triterpenes, cardenolides, and dienolides were not detected. In the castor oil-induced diarrhoeal model, the sap significantly (P<0.05 prolonged the onset time of diarrhoea, decreased the number, fresh weight, and water content of feaces, and increased the inhibition of defecations. Na+-K+-ATPase activity in the small intestine increased significantly whereas nitric oxide content decreased. The decreases in the masses and volumes of intestinal fluid by the sap were accompanied by increase in inhibition of intestinal fluid content in the enteropooling model. The sap decreased the charcoal meal transit in the gastrointestinal motility model. In all the models, the 1.00 mL of the sap produced changes that compared well with the reference drugs. Overall, the antidiarrhoeal activity of Musa paradisiaca sap attributed to the presence of alkaloids, phenolics, flavonoids, and/or saponins which may involve, among others, enhancing fluid and electrolyte absorption through de novo synthesis of the sodium potassium ATPase and/or reduced nitric oxide levels.

  17. SAP ERP financial accounting and controlling configuration and use management

    CERN Document Server

    Okungbowa, Andrew

    2015-01-01

    SAP ERP modules are notoriously hard to configure and use effectively without a lot of practice and experience. But as SAP ERP Financial Accounting and Controlling: Configuration and Use Management shows, it doesn't have to be so difficult. The book takes a systematic approach that leads SAP Financial Accounting and Controlling (FICO) users step by step through configuring and using all the program's facets. This approach makes configuration complexities manageable. The book's author-SAP expert, trainer, and accountant Andrew Okun

  18. Nye integrerede ledelsesinformationssystemer SAP/R3

    DEFF Research Database (Denmark)

    Nielsen, Steen

    1998-01-01

    Artiklen beskriver og analyserer hovedindholdet i SAP/R3's controlling modul, speciel med sigte på hvilke forudsætninger systemet bygger på, dels med reference til den danske lønsomheds- og kapacitetsmodel.......Artiklen beskriver og analyserer hovedindholdet i SAP/R3's controlling modul, speciel med sigte på hvilke forudsætninger systemet bygger på, dels med reference til den danske lønsomheds- og kapacitetsmodel....

  19. Assessing the ERP-SAP implementation strategy from cultural perspectives

    Science.gov (United States)

    Wang, Gunawan; Syaiful, Bakhri; Sfenrianto; Nurul, Fajar Ahmad

    2017-09-01

    Implementing ERP-SAP projects in Indonesian large enterprises frequently create headaches for the consultants, since there are always be a large gap between the outcomes of the SAP with the expected results. Indonesian enterprises have experience with a huge amount of investments and ended up with minor benefits. Despite its unprecedented benefits, the SAP strategy is still considered as a mandatory enterprise system for every enterprise to compete in the marketplaces. The article examines the SAP implementation from cultural perspectives to present new horizon that commonly ignored by major Indonesian enterprises. The article applies the multiple case studies with three large Indonesia enterprises, such as KS, the largest steel producer; GEM, a subsidiary of conglomerate enterprise operates in the mining industry, and HS, a subsidiary of the largest retailer in Asia with more than 700 stores in Indonesia. The outcome of the article is expected to provide a comprehensive analysis from cultural perspectives regarding to common problems faced by SAP consultants.

  20. Groundwater sapping channels: Summary of effects of experiments with varied stratigraphy

    Science.gov (United States)

    Kochel, R. Craig; Simmons, David W.

    1987-01-01

    Experiments in the recirculating flume sapping box have modeled valley formation by groundwater sapping processes in a number of settings. The effects of the following parameters on sapping channel morphology were examined: surface slope; stratigraphic variations in permeability cohesion and dip; and structure of joints and dikes. These kinds of modeling experiments are particularly good for: testing concepts; developing a suite of distinctive morphologies and morphometries indicative of sapping; helping to relate process to morphology; and providing data necessary to assess the relative importance of runoff, sapping, and mass wasting processes on channel development. The observations from the flume systems can be used to help interpret features observed in terrestrial and Martian settings where sapping processes are thought to have played an important role in the development of valley networks.

  1. 49 CFR 40.285 - When is a SAP evaluation required?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false When is a SAP evaluation required? 40.285 Section... § 40.285 When is a SAP evaluation required? (a) As an employee, when you have violated DOT drug and... unless you complete the SAP evaluation, referral, and education/treatment process set forth in this...

  2. SAPS effects on thermospheric winds during the 17 March 2013 storm

    Science.gov (United States)

    Sheng, C.; Lu, G.; Wang, W.; Doornbos, E.; Talaat, E. R.

    2017-12-01

    Strong subauroral polarization streams (SAPS) were observed by DMSP satellites during the main phase of the 17 March 2013 geomagnetic storm. Both DMSP F18 and GOCE satellites sampled at 19 MLT during this period, providing near-simultaneous measurements of ion drifts and neutral winds near dusk. The fortuitous satellite conjunction allows us to directly examine the SAPS effects on thermospheric winds. In addition, two sets of model runs were carried out for this event: (1) the standard TIEGCM run with high-latitude forcing; (2) the SAPS-TIEGCM run by incoporating an empirical model of SAPS in the subauroral zone. The difference between these two runs represents the influence of SAPS forcing. In particular, we examine ion-neutral coupling at subauroral latitudes through detailed forcing term analysis to determine how the SAPS-related strong westward ion drifts alter thermospheric winds.

  3. Collection of pure phloem sap from wheat and its chemical composition

    International Nuclear Information System (INIS)

    Hayashi, H.; Chino, M.

    1986-01-01

    Wheat Phloem sap was collected without contamination from the stylets of small brown planthopper severed by a YAG laser beam. The sugar, amino acid and inorganic ion composition was determined using only one μl of the sap. The sap had a high sucrose level (251 mM), and also a high K+ level (299 mM). Total amino acid compounds in the sap reached 262 mM. The dominant amino acids were glutamic acid, aspartic acid and serine, while r-amino butylic acid was absent. The major anion in the sap was Cl− and its concentration was 25.1 mM. Nitrate was also present at a concentration of 8.1 mM. These results suggested that the sap obtained from the cut end of the stylets of the small brown planthopper was a phloem origin of wheat. (author)

  4. Mass Spectrometry-Based Metabolomics of Agave Sap (Agave salmiana after Its Inoculation with Microorganisms Isolated from Agave Sap Concentrate Selected to Enhance Anticancer Activity

    Directory of Open Access Journals (Sweden)

    Luis M. Figueroa

    2017-11-01

    Full Text Available Saponins have been correlated with the reduction of cancer cell growth and the apoptotic effect of agave sap concentrate. Empirical observations of this artisanal Mexican food have shown that fermentation occurs after agave sap is concentrated, but little is known about the microorganisms that survive after cooking, or their effects on saponins and other metabolites. The aim of this study was to evaluate the changes in metabolites found in agave (A. salmiana sap after its fermentation with microorganisms isolated from agave sap concentrate, and demonstrate its potential use to enhance anticancer activity. Microorganisms were isolated by dilution plating and identified by 16S rRNA analysis. Isolates were used to ferment agave sap, and their corresponding butanolic extracts were compared with those that enhanced the cytotoxic activity on colon (Caco-2 and liver (Hep-G2 cancer cells. Metabolite changes were investigated by mass spectrometry-based metabolomics. Among 69 isolated microorganisms, the actinomycetes Arthrobacter globiformis and Gordonia sp. were used to analyze the metabolites, along with bioactivity changes. From the 939 ions that were mainly responsible for variation among fermented samples at 48 h, 96 h, and 192 h, four were correlated to anticancer activity. It was shown that magueyoside B, a kammogenin glycoside, was found at higher intensities in the samples fermented with Gordonia sp. that reduced Hep-G2 viability better than controls. These findings showed that microorganisms from agave sap concentrate change agave sap metabolites such as saponins. Butanolic extracts obtained after agave sap fermentation with Arthrobacter globiformis or Gordonia sp. increased the cancer cell growth inhibitory effect on colon or liver cancer cells, respectively.

  5. Five years' experience of the new SAPs: overview and way forward

    International Nuclear Information System (INIS)

    Pape, R.P.

    1998-01-01

    This paper gives an overview of the five years' experience gained in applying the new safety assessment principles (SAPs). Beginning with a brief history of SAPs, it goes on to discuss their structure and their relevance to safety matters. It develops some of the more basic issues which users have to bear in mind and also considers how SAPs are used by NII. Finally, there is a look forward to future developments in SAPs usage and application. (author)

  6. The effects of climate change on agriculture, land resources, water resources, and biodiversity in the United States

    Science.gov (United States)

    2008-06-01

    This report provides an assessment of the effects of climate change on U.S. agriculture, land resources, water resources, and biodiversity. It is one of a series of 21 Synthesis and Assessment Products (SAP) that are being produced under the auspices...

  7. Conservation of element concentration in xylem sap of red spruce

    Science.gov (United States)

    Kevin T. Smith; Walter C. Shortle

    2001-01-01

    We investigated the chemistry of xylem sap as a marker of red spruce metabolism and soil chemistry at three locations in northern New England. A Scholander pressure chamber was used to extract xylem sap from roots and branches cut from mature trees in early June and September. Root sap contained significantly greater concentrations of K, Ca, Mg, Mn, and A1 than branch...

  8. Gender Analysis Of Electronic Information Resource Use: The Case ...

    African Journals Online (AJOL)

    Based on the findings the study concluded that access and use of electronic information resources creates a “social digital divide” along gender lines. The study ... Finally, the library needs to change its marketing strategies on the availability of electronic information resources to increase awareness of these resources.

  9. ERP SAP-osaamisen kehittäminen Pohjois-Karjalan ammattikorkeakoulussa

    OpenAIRE

    Nuutinen, Päivi

    2012-01-01

    Opinnäytetyön tavoitteena oli tutkia, millä toimin Pohjois-Karjalan ammattikorkeakoulun liiketalouden ja tekniikan keskuksen opetushenkilöstön ERP SAP-osaamista on kehitetty ja vastaako osaaminen ulkoisten asiakkaiden tarpeisiin. Tutkimustavoitteena oli selvittää myös ne menetelmät, jotka opetushenkilöstö kokee parhaimpina ERP SAP-osaamisen kehittämisen keinoina. ERP SAP-osaamisen kehittämisessä huomioitiin ulkoisten asiakkuuksien näkemykset. Tutkimustulosten osalta tuli esille, että ty...

  10. 49 CFR 40.281 - Who is qualified to act as a SAP?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Who is qualified to act as a SAP? 40.281 Section... § 40.281 Who is qualified to act as a SAP? To be permitted to act as a SAP in the DOT drug and alcohol.... (2) You must be knowledgeable about the SAP function as it relates to employer interests in safety...

  11. Users satisfaction with electronic information resources and services ...

    African Journals Online (AJOL)

    This study investigated users satisfaction on the use of electronic information resources and services in MTN Net libraries in ABU & UNIBEN. Two objectives and one null hypotheses were formulated and tested with respect to the users' satisfaction on electronic information resources and services in MTN Net libraries in ...

  12. Potential of Jatropha multifida sap against traumatic ulcer

    Directory of Open Access Journals (Sweden)

    Basri A. Gani

    2015-09-01

    Full Text Available Background: Traumatic ulcer is a lesion in oral mucosa as a result of physical and mechanical trauma, as well as changes in salivary pH. Jatropha multifida sap can act as antimicrobial, anti-inflammatory and re-epithelialization, and can also trigger the healing process of ulcers. Purpose: Research was aimed to determine the potential of Jatropha multifida sap against traumatic ulcer base on clinical and histopathological healing process. Method: This research was conducted laboratory experimental model, with rats (Rattus norvegicus as the subject as well as Jatropha multifida sap for ulcer healing. Those subjects were divided into four groups: two treatment groups administrated with pellet and Jatropha multifida sap, one group as the positive control group administrated with 0.1% triamcinolone acetonide, and one group as the negative control group administrated with 0.9% NaCl. Ulcer manipulation was used 30% H2O2, and evaluation of ulcer healing was used clinical and histopathological approach. Result: Clinically, the healing process of ulcers in the treatment group with Jatropha multifida sap was faster than that in the positive control group with 0.1% triamcinolone acetonide, indicated with the reduction of the ulcer size until the missing of the ulcers started from the third day to the seventh one (p≤0.05. Histopathologically inflammatory cells (lymphocytes, and plasma cells declined started from the third day, and the formation of collagen and re-epithelialization then occurred. On the seventh day, the epithelial cells thickened, and the inflammatory cells infiltrated. Statistically, those groups were significant (p≤0.05. Conclusion: Jatropha multifida sap has a significant potential to cure traumatic ulcers on oral mucosa clinically and histopathologically.

  13. Extensive investigation of the sap flow of maize plants in an oasis farmland in the middle reach of the Heihe River, Northwest China.

    Science.gov (United States)

    Zhao, Liwen; He, Zhibin; Zhao, Wenzhi; Yang, Qiyue

    2016-09-01

    A better understanding of the sap flow characteristics of maize plants is critical for improving irrigation water-use efficiency, especially for regions facing water resource shortages. In this study, sap flow rates, related soil-physics and plant-growth parameters, and meteorological factors, were simultaneously monitored in a maize field in two consecutive years, 2011 and 2012, and the sap flow rates of the maize plants were extensively analyzed based on the monitored data. Seasonal and daily variational characteristics were identified at different growth stages and under different weather conditions, respectively. The analyses on the relationships between sap flow rate and reference evapotranspiration (ET0), as well as several plant-growth parameters, indicate that the irrigation schedule can exert an influence on sap flow, and can consequently affect crop yield. The ranking of the main meteorological factors affecting the sap flow rate was: net radiation > air temperature > vapor pressure deficit > wind speed. For a quick estimation of sap flow rates, an empirical formula based on the two top influencing factors was put forward and verified to be reliable. The sap flow rate appeared to show little response to irrigation when the water content was relatively high, implying that some of the irrigation in recent years may have been wasted. These results may help to reveal the bio-physical processes of maize plants related to plant transpiration, which could be beneficial for establishing an efficient irrigation management system in this region and also for providing a reference for other maize-planting regions.

  14. Strategi Perencanaan Pengembangan Sistem Sap pada Human Capital and Legal di Institusi Pendidikan Xyz

    Directory of Open Access Journals (Sweden)

    Evy Ekawati

    2014-06-01

    Full Text Available The increasing complexity of processes and operational functions cause arises the need for an integrated information system across all functional areas to reach the highest point of effectiveness and efficiency, and relying on the information in making decisions, ie ERP (Enterprise Resource Planning. The objective of writing this journal is to analyze and determine a SAP system development strategy planning at Human Capital and Legal of Education Institution XYZ. In collecting data, the author collected the datas by making an interview with the sources, data observation, and SAP system exploration. Current architecture datas that were collected and anylized to design the planning strategy in developing system architecture. The conclusion of this journal writing is that planning with some methodologies could maximize the using of IS or IT in an organization and can achieve its goals.

  15. Tree Species with Photosynthetic Stems Have Greater Nighttime Sap Flux

    Directory of Open Access Journals (Sweden)

    Xia Chen

    2018-01-01

    Full Text Available An increasing body of evidence has shown that nighttime sap flux occurs in most plants, but the physiological implications and regulatory mechanism are poorly known. The significance of corticular photosynthesis has received much attention during the last decade, however, the knowledge of the relationship between corticular photosynthesis and nocturnal stem sap flow is limited at present. In this study, we divided seven tree species into two groups according to different photosynthetic capabilities: trees of species with (Castanopsis hystrix, Michelia macclurei, Eucalyptus citriodora, and Eucalyptus grandis × urophylla and without (Castanopsis fissa, Schima superba, and Acacia auriculiformis photosynthetic stems, and the sap flux (Js and chlorophyll fluorescence parameters for these species were measured. One-way ANOVA analysis showed that the Fv/Fm (Maximum photochemical quantum yield of PSII and ΦPSII (effective photochemical quantum yield of PSII values were lower in non-photosynthetic stem species compared to photosynthetic stem species. The linear regression analysis showed that Js,d (daytime sap flux and Js,n (nighttime sap flux of non-photosynthetic stem species was 87.7 and 60.9% of the stem photosynthetic species. Furthermore, for a given daytime transpiration water loss, total nighttime sap flux was higher in species with photosynthetic stems (SlopeSMA = 2.680 than in non-photosynthetic stems species (SlopeSMA = 1.943. These results mean that stem corticular photosynthesis has a possible effect on the nighttime water flow, highlighting the important eco-physiological relationship between nighttime sap flux and corticular photosynthesis.

  16. An Auroral Boundary-Oriented Model of Subauroral Polarization Streams (SAPS)

    Science.gov (United States)

    Landry, R. G.; Anderson, P. C.

    2018-04-01

    An empirical model of subauroral polarization stream (SAPS) electric fields has been developed using measurements of ion drifts and particle precipitation made by the Defense Meteorological Satellite Program from 1987 to 2012 and Dynamics Explorer 2 as functions of magnetic local time (MLT), magnetic latitude, the auroral electrojet index (AE), hemisphere, and day of year. Over 500,000 subauroral passes are used. This model is oriented in degree magnetic latitude equatorward of the aurora and takes median values instead of the mean to avoid the contribution of low occurrence frequency subauroral ion drifts so that the model is representative of the much more common, latitudinally broad, low-amplitude SAPS field. The SAPS model is in broad agreement with previous statistical efforts in the variation of the SAPS field with MLT and magnetic activity level, although the median field is weaker. Furthermore, we find that the median SAPS field is roughly conjugate in both hemispheres for all seasons, with a maximum in SAPS amplitude and width found for 1800-2000 MLT. The SAPS amplitude is found to vary seasonally only from about 1800-2000 MLT, maximizing in both hemispheres during equinox months. Because this feature exists despite controlling for the AE index, it is suggested that this is due to a seasonal variation in the flux tube averaged ionospheric conductance at MLT sectors where it is more likely that one flux tube footprint is in darkness while the other is in daylight.

  17. Tree Species with Photosynthetic Stems Have Greater Nighttime Sap Flux

    Science.gov (United States)

    Chen, Xia; Gao, Jianguo; Zhao, Ping; McCarthy, Heather R.; Zhu, Liwei; Ni, Guangyan; Ouyang, Lei

    2018-01-01

    An increasing body of evidence has shown that nighttime sap flux occurs in most plants, but the physiological implications and regulatory mechanism are poorly known. The significance of corticular photosynthesis has received much attention during the last decade, however, the knowledge of the relationship between corticular photosynthesis and nocturnal stem sap flow is limited at present. In this study, we divided seven tree species into two groups according to different photosynthetic capabilities: trees of species with (Castanopsis hystrix, Michelia macclurei, Eucalyptus citriodora, and Eucalyptus grandis × urophylla) and without (Castanopsis fissa, Schima superba, and Acacia auriculiformis) photosynthetic stems, and the sap flux (Js) and chlorophyll fluorescence parameters for these species were measured. One-way ANOVA analysis showed that the Fv/Fm (Maximum photochemical quantum yield of PSII) and ΦPSII (effective photochemical quantum yield of PSII) values were lower in non-photosynthetic stem species compared to photosynthetic stem species. The linear regression analysis showed that Js,d (daytime sap flux) and Js,n (nighttime sap flux) of non-photosynthetic stem species was 87.7 and 60.9% of the stem photosynthetic species. Furthermore, for a given daytime transpiration water loss, total nighttime sap flux was higher in species with photosynthetic stems (SlopeSMA = 2.680) than in non-photosynthetic stems species (SlopeSMA = 1.943). These results mean that stem corticular photosynthesis has a possible effect on the nighttime water flow, highlighting the important eco-physiological relationship between nighttime sap flux and corticular photosynthesis. PMID:29416547

  18. Auditoria fiscal previdenciária em ambiente SAP

    Directory of Open Access Journals (Sweden)

    Alexandre David Viva

    2006-12-01

    Full Text Available Este trabalho busca identificar meios para efetuar auditoria fiscal nos bancos de dados do SAP - o mais adotado ERP da atualidade (Bae e Ashcroft, 2004, 1 e 5; Khan, 2005, 5. Pretende-se concentrar no método de acesso às tabelas SAP, um dos cinco métodos de acesso aos bancos de dados de ERP (Neil Raden, 2004, 10. Em um primeiro momento, é necessário o levantamento, por empresa, de uma listagem dos cabeçalhos das tabelas com as quais ela trabalha, em bancos de dados que já alcançam os terabytes (SAP, SAP NetWeaver: 50. Como o SAP é um programa multilíngüe e multiempresarial, suas tabelas são criptografadas, isto é, os nomes das tabelas e de duas colunas não guardam a menor relação com os dados que elas registram (Saphir, 2004, 1. Em um segundo momento, então, por meio do ACL, a listagem de cabeçalhos de tabelas obtida é filtrada. As tabelas que interessam ao Fisco são solicitadas à empresa de uma forma mais precisa, de modo a não sobrecarregar nem a empresa nem do Fisco. Em um terceiro momento, ainda com auxílio do ACL, as tabelas especificadas são analisadas (Primeiros Passos, 2003, 3.

  19. Handling of the demilitarized zone using service providers in SAP

    Science.gov (United States)

    Iovan, A.; Robu, R.

    2016-02-01

    External collaboration needs to allow data access from the Internet. In a trusted Internet collaboration scenario where the external user works on the same data like the internal user direct access to the data in the Intranet is required. The paper presents a solution to get access to certain data in the Enterprise Resource Planning system, having the User Interface on a system in the Demilitarized Zone and the database on a system which is located in the trusted area. Using the Service Provider Interface framework, connections between separate systems can be created in different areas of the network. The paper demonstrates how to connect the two systems, one in the Demilitarized Zone and one in the trusted area, using SAP ERP 6.0 with Enhancement Package 7. In order to use the Service Provider Interface SAP Business Suite Foundation component must be installed in both systems. The advantage of using the Service Provider Interface framework is that the external user works on the same data like the internal user (and not on copies). This assures data consistency and less overhead for backup and security systems.

  20. A global database of sap flow measurements (SAPFLUXNET) to link plant and ecosystem physiology

    Science.gov (United States)

    Poyatos, Rafael; Granda, Víctor; Flo, Víctor; Molowny-Horas, Roberto; Mencuccini, Maurizio; Oren, Ram; Katul, Gabriel; Mahecha, Miguel; Steppe, Kathy; Martínez-Vilalta, Jordi

    2017-04-01

    Regional and global networks of ecosystem CO2 and water flux monitoring have dramatically increased our understanding of ecosystem functioning in the last 20 years. More recently, analyses of ecosystem-level fluxes have successfully incorporated data streams at coarser (remote sensing) and finer (plant traits) organisational scales. However, there are few data sources that capture the diel to seasonal dynamics of whole-plant physiology and that can provide a link between organism- and ecosystem-level function. Sap flow measured in plant stems reveals the temporal patterns in plant water transport, as mediated by stomatal regulation and hydraulic architecture. The widespread use of thermometric methods of sap flow measurement since the 1990s has resulted in numerous data sets for hundreds of species and sites worldwide, but these data have remained fragmentary and generally unavailable for syntheses of regional to global scope. We are compiling the first global database of sub-daily sap flow measurements in individual plants (SAPFLUXNET), aimed at unravelling the environmental and biotic drivers of plant transpiration regulation globally. I will present the SAPFLUXNET data infrastructure and workflow, which is built upon flexible, open-source computing tools within the R environment (dedicated R packages and classes, interactive documents and apps with Rmarkdown and Shiny). Data collection started in mid-2016, we have already incorporated > 50 datasets representing > 40 species and > 350 individual plants, globally distributed, and the number of contributed data sets is increasing rapidly. I will provide a general overview of the distribution of available data sets according to climate, measurement method, species, functional groups and plant size attributes. In parallel to the sap flow data compilation, we have also collated published results from calibrations of sap flow methods, to provide a first quantification on the variability associated with different sap

  1. The Effect of Sub-Auroral Polarization Streams (SAPS) on Ionosphere and Thermosphere during 2015 St. Patrick's Day storm: Global Ionosphere-Thermosphere Model (GITM) Simulations

    Science.gov (United States)

    Guo, J.; Deng, Y.; Zhang, D.; Lu, Y.; Sheng, C.

    2017-12-01

    Sub-Auroral Polarization Streams (SAPS) are incorporated into the non-hydrostatic Global Ionosphere-Thermosphere Model (GITM), revealing the complex effects on neutral dynamics and ion-neutral coupling processes. The intense westward ion stream could enhance the neutral zonal wind within the SAPS channel. Through neutral dynamics the neutrals then divide into two streams, one turns poleward and the other turns equatorward, forming a two-cell pattern in the SAPS-changed wind. The significant Joule heating induced by SAPS also leads to traveling atmospheric disturbances (TAD) accompanied by traveling ionospheric disturbances (TID), increasing the total electron content (TEC) by 2-8 TECu in the mid-latitude ionosphere. We investigate the potential causes of the reported poleward wind surge during the St. Patrick's Day storm in 2015. It is confirmed that Coriolis force on the westward zonal wind can contribute the poleward wind during post-SAPS interval. In addition, the simulations imply that the sudden decrease of heating rate within auroral oval could result in a TAD propagating equatorward, which could also be responsible for the sudden poleward wind surge. This study highlights the complicated effects of SAPS on ion-neutral coupling and neutral dynamics.

  2. SAP Suppresses the Development of Experimental Autoimmune Encephalomyelitis in C57BL6 Mice

    Science.gov (United States)

    Ji, Zhe; Ke, Zun-Ji; Geng, Jian-Guo

    2012-01-01

    Experimental autoimmune encephalomyelitis (EAE) is a CD4+ T cell-mediated disease of the CNS. Serum amyloid P component (SAP) is a highly conserved plasma protein named for its universal presence in amyloid deposits. Here we report SAP transgenic mice had unexpectedly attenuated EAE due to impaired encephalitogenic responses. Following induction with myelin oligodendroglial glycoprotein (MOG) peptide 35–55 in CFA, SAP transgenic mice showed reduced spinal cord inflammation with lower severity of EAE attacks as compared with control C57BL/6 mice. However in SAP-KO mice, the severity of EAE is enhanced. Adoptive transfer of Ag-restimulated T cells from wild-type to SAP transgenic mice or transfer of SAP transgenic Ag-restimulated T cells to control mice induced milder EAE. T cells from MOG-primed SAP transgenic mice showed weak proliferative responses. Furthermore, in SAP transgenic mice, there is little infiltration of CD45-positive cells in the spinal cord. In vitro, SAP suppressed the secretion of IL-2 stimulated by P-selectin, and blocked P-selectin binding to T cells. Moreover, SAP could change the affinity between α4-integrin and T cells. These data suggested that SAP could antagonize the development of the acute phase of inflammation accompanying EAE by modulating the function of P-selectin. PMID:21647172

  3. Accumulation of sphingolipid activator proteins (SAPs) A and D in granular osmiophilic deposits in miniature Schnauzer dogs with ceroid-lipofuscinosis.

    Science.gov (United States)

    Palmer, D N; Tyynelä, J; van Mil, H C; Westlake, V J; Jolly, R D

    1997-03-01

    The neuronal ceroid-lipofuscinoses (NCL, Batten disease) are fatal inherited neurodegenerative diseases of children characterized by retinal and brain atrophy and the accumulation of electron-dense storage bodies in cells. Mutations in different genes underlie different major forms. The infantile disease (CLN-1, McKusick 256730) is distinguished by the storage of the sphingolipid activator proteins (SAPs) A and D in distinctive granular osmiophilic deposits (GRODs). This contrasts with the other major forms, where subunit c of mitochondrial ATP synthase is stored in various multilamellar profiles. Ceroid-lipofuscinoses also occur in dogs, including a form in miniature Schnauzers with distinctive granular osmiophilic deposit-like storage bodies. Antisera to SAPs A and D reacted to these storage bodies in situ. The presence of SAP D was confirmed by Western blotting and of SAP A by protein sequencing. Neither subunit c of mitochondrial ATP synthase nor of vacuolar ATPase is stored. This suggests that there are two families of ceroid-lipofuscinoses, the subunit c-storing forms, and those in which SAPs A and D, and perhaps other proteins, accumulate. Further work is required to determine whether other forms with granular osmiophilic deposits belong to the latter class and the genetic relationships between them and the human infantile disease.

  4. Revaluasi Inventory dengan Menu Standard pada SAP-B1 Sesuaikah dengan IFRS

    Directory of Open Access Journals (Sweden)

    Eka Novianti

    2011-05-01

    Full Text Available Some available standard modules in SAP-B1 can be adapted for changes in accounting rules and regulations. One is the Inventory Revaluation menu of Inventory module. Users can use the menu to make Inventory value adjustments of value in SAP-B1, to be consistent with the values that must be presented in the financial statements. Based on the flexibility provided by SAP-B1menu, should not be too difficult for users of SAP-B1 to manage accounting transactions based on accounting rules that apply today, IFRS. IFRS requirements on inventory adjustment transactions with a value of SAP-B1 could be done more easily.

  5. Characterization and vaccine potential of Fasciola gigantica saposin-like protein 1 (SAP-1).

    Science.gov (United States)

    Kueakhai, Pornanan; Changklungmoa, Narin; Waseewiwat, Pinkamon; Thanasinpaiboon, Thanaporn; Cheukamud, Werachon; Chaichanasak, Pannigan; Sobhon, Prasert

    2017-01-15

    The recombinant Fasciola gigantica Saposin-like protien-1 (rFgSAP-1) was cloned by polymerase chain reaction (PCR) from NEJ cDNA, expressed in Escherichia coli BL21 (DE3) and used for production of a polyclonal antibody in rabbits (anti-rFgSAP-1). By immunoblotting and immunohistochemistry, rabbit IgG anti-rFgSAP-1 reacted with rFgSAP-1 at a molecular weight 12kDa, but not with rFgSAP-2. The rFgSAP-1 reacted with antisera from mouse infected with F. gigantica metacercariae collected at 2, 4, and 6 weeks after infection. The FgSAP-1 protein was expressed at a high level in the caecal epithelium of metacercariae and NEJs. The vaccination was performed in Imprinting Control Region (ICR) mice (n=10) by subcutaneous injection with 50μg of rFgSAP-1 combined with Alum adjuvant. Two weeks after the second boost, mice were infected with 15 metacercariae per mouse by the oral route. The percents protection of rFgSAP-1 vaccine were estimated to be 73.2% and 74.3% when compared with non vaccinated-infected and adjuvant-infected controls, respectively. The levels of IgG1 and IgG2a specific to rFgSAP-1 in the immune sera, which are indicative of Th2 and Th1 immune responses, were inversely and significantly correlated with the numbers of worm recoveries. The rFgSAP-1-vaccinated mice showed significantly reduced levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), and liver damage. These indicated that rFgSAP-1 has strong potential as a vaccine candidate against F. gigantica, whose efficacy will be studied further in large economic animals including cattle, sheep, and goat. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Liquid effluent Sampling and Analysis Plan (SAP) implementation summary report

    International Nuclear Information System (INIS)

    Lueck, K.J.

    1995-01-01

    This report summarizes liquid effluent analytical data collected during the Sampling and Analysis Plan (SAP) Implementation Program, evaluates whether or not the sampling performed meets the requirements of the individual SAPs, compares the results to the WAC 173-200 Ground Water Quality Standards. Presented in the report are results from liquid effluent samples collected (1992-1994) from 18 of the 22 streams identified in the Consent Order (No. DE 91NM-177) requiring SAPs

  7. Tree Species with Photosynthetic Stems Have Greater Nighttime Sap Flux.

    Science.gov (United States)

    Chen, Xia; Gao, Jianguo; Zhao, Ping; McCarthy, Heather R; Zhu, Liwei; Ni, Guangyan; Ouyang, Lei

    2018-01-01

    An increasing body of evidence has shown that nighttime sap flux occurs in most plants, but the physiological implications and regulatory mechanism are poorly known. The significance of corticular photosynthesis has received much attention during the last decade, however, the knowledge of the relationship between corticular photosynthesis and nocturnal stem sap flow is limited at present. In this study, we divided seven tree species into two groups according to different photosynthetic capabilities: trees of species with ( Castanopsis hystrix, Michelia macclurei, Eucalyptus citriodora , and Eucalyptus grandis × urophylla ) and without ( Castanopsis fissa, Schima superba , and Acacia auriculiformis ) photosynthetic stems, and the sap flux ( J s ) and chlorophyll fluorescence parameters for these species were measured. One-way ANOVA analysis showed that the F v / F m (Maximum photochemical quantum yield of PSII) and Φ PSII (effective photochemical quantum yield of PSII) values were lower in non-photosynthetic stem species compared to photosynthetic stem species. The linear regression analysis showed that J s,d (daytime sap flux) and J s,n (nighttime sap flux) of non-photosynthetic stem species was 87.7 and 60.9% of the stem photosynthetic species. Furthermore, for a given daytime transpiration water loss, total nighttime sap flux was higher in species with photosynthetic stems (Slope SMA = 2.680) than in non-photosynthetic stems species (Slope SMA = 1.943). These results mean that stem corticular photosynthesis has a possible effect on the nighttime water flow, highlighting the important eco-physiological relationship between nighttime sap flux and corticular photosynthesis.

  8. Superabsorbent polymers (SAP) enhance efficient and eco-friendly ...

    African Journals Online (AJOL)

    In arid and semiarid regions of northern China, there is an increasing interest in using reduced rate of chemical fertilizer along with water-saving superabsorbent polymer (SAP) for field crop production. The objective was to evaluate the effectiveness of different rates of SAP (low, 0.75; medium, 11.3 and high, 15.0 kg ha-1) ...

  9. Organizational matters of competition in electronic educational resources

    Directory of Open Access Journals (Sweden)

    Ирина Карловна Войтович

    2015-12-01

    Full Text Available The article examines the experience of the Udmurt State University in conducting competitions of educational publications and electronic resources. The purpose of such competitions is to provide methodological support to educational process. The main focus is on competition of electronic educational resources. The technology of such contests is discussed through detailed analysis of the main stages of the contest. It is noted that the main task of the preparatory stage of the competition is related to the development of regulations on competition and the definition of criteria for selection of the submitted works. The paper also proposes a system of evaluation criteria of electronic educational resources developed by members of the contest organizing committee and jury members. The article emphasizes the importance of not only the preparatory stages of the competition, but also measures for its completion, aimed at training teachers create quality e-learning resources.

  10. Intermolecular crosslinks mediate aggregation of phospholipid vesicles by pulmonary surfactant-associated protein SAP-35

    International Nuclear Information System (INIS)

    Ross, G.R.; Sawyer, J.; Whitsett, J.

    1987-01-01

    Pulmonary surfactant-associated protein, Mr=35,000 (SAP-35) is known to bind phospholipids and is hypothesized to function in the organization of surfactant lipid membranes. SAP-35 has been observed to accelerate the calcium-induced aggregation of phospholipid vesicles. In order to define the molecular domains of SAP-35 which function in phospholipid aggregation, they have measured the light scattering properties (400nm) of purified canine SAP-35-phospholipid vesicle suspensions. Accelerated aggregation of unilamellar vesicles, requires SAP-35 and at least 2mM free calcium. The initial rate of A 400 change is proportional to the amount of native SAP-35 added over lipid:protein molar ratios ranging from 100:1 to 5000:1. Removal of the SAP-35 collagen-like domain and a specific cysteine residue involved in intermolecular disulfide bonding by bacterial collagenase digestion destroys the protein's lipid aggregation activity. Pre-incubation of SAP-35 with dithiothreitol (DTT) under nondenaturing conditions also results in a time-dependent loss of aggregation activity. Sucrose density gradient floatation of SAP-35 with 14 C dipalmitoyl phosphatidycholine labelled vesicles in the absence or presence of DTT suggests retention of SAP-35 lipid binding capacity. These data demonstrate the importance of SAP-35 triple helix and disulfide crosslinking integrity for the aggregation of unilamellar phospholipid vesicles

  11. Shelf life extension and sensory evaluation of birch tree sap using chemical preservatives

    Directory of Open Access Journals (Sweden)

    Maciej Bilek

    2016-10-01

    Full Text Available The aim of this study was to assess the stability of the birch tree sap, depending on the addition and concentration of two chemical factors, ie. potassium sorbate and acids: malic, citric or lactic. As in our previous studies we found that the optimal physical parameter to assess the stability of birch sap is turbidity measurement, we used turbidimeter for estimate the effectiveness of shelf life extending. Sensory evaluation was carried out by university sensory panel with 8 skilled people (students and teachers with pre-selection and basic training of sensory methodology. On the other hand artificial perception measurements were realized by electronic nose. Birch tree sap stability without addition of preservatives, both room temperature and refrigerated, is less than three days. The effectiveness of preservation of birch tree sap depends on the concentration of acids. Independently of storage temperature, samples that received stability during the whole one-month storage period, were those with potassium sorbate and three acids in the highest concentrations, ie. malic acid at 0.3%, citric acid at 0.5% and lactic acid at 0.5%. Unfortunately, concentrations of acids, which allow extension of shelf life at least for one month in a room temperature, are characterized by the worst sensory evaluation rating. Thus, they should be corrected by the use of additives for improving the flavor, such as fruit syrups or herbal extracts. On the other hand, additionally storage in a refrigerated conditions allows one-month-stability for the sample with the highest sensory evaluation rating, ie. with the addition of lactic acid at 0.1% and potassium sorbate, which taste not need to be corrected.

  12. La proteína asociada a SLAM (SAP regula la expresión de IFN-g en lepra The SLAM-associated protein (SAP regulates IFN-g expression in leprosy

    Directory of Open Access Journals (Sweden)

    María F. Quiroga

    2004-10-01

    Full Text Available La inmunidad protectora contra Mycobacterium leprae requiere IFN-g. Los pacientes con lepra tuberculoide producen localmente citoquinas Th1, mientras que los pacientes lepromatosos producen citoquinas Th2. La molécula linfocitaria activadora de señales (SLAM y la proteína asociada a SLAM (SAP participan en la diferenciación celular que conduce a producción de patrones específicos de citoquinas. A fin de investigar la vía SLAM/SAP en la infección por M. leprae, determinamos expresión de ARN mensajero (ARNm de SAP, IFN-g y SLAM en pacientes con lepra. Observamos que la expresión de SLAM correlacionó en forma directa con la expresión de IFN-g, mientras que la expresión de SAP correlacionó inversamente con la expresión de ambas proteínas. Así, nuestros resultados indican que SAP interferiría con las respuestas de citoquinas Th1 mientras que SLAM contribuiría con la respuesta Th1 en lepra, señalando a la vía SLAM/SAP como potencial blanco modulador de citoquinas en enfermedades con respuestas Th2 disfuncionales.Tuberculoid leprosy patients locally produce Th1 cytokines, while lepromatous patients produce Th2 cytokines. Signaling lymphocytic activation molecule (SLAM and the SLAM-associated protein (SAP participate in the differentiation process that leads to the production of specific patterns of cytokines by activated T cells. To investigate the SLAM/SAP pathway in M. leprae infection, we determined the expression of SAP, IFN-g and SLAM RNA messenger in leprosy patients. We found a direct correlation of SLAM expression with IFN-g expression, whereas the expression of SAP was inversely correlated with the expression of both SLAM and IFN-g. Therefore, our data indicate that SAP might interfere with Th1 cytokine responses while SLAM expression may contribute to Th1 responses in leprosy. This study further suggests that the SLAM/SAP pathway might be a focal point for therapeutic modulation of T cell cytokine responses in diseases

  13. Arsenic speciation in xylem sap of cucumber (Cucumis sativus L.)

    Energy Technology Data Exchange (ETDEWEB)

    Mihucz, Victor G. [Joint Research Group of Environmental Chemistry of the Hungarian Academy of Sciences and L. Eoetvoes University, Budapest (Hungary); Hungarian Satellite Centre of Trace Elements Institute to UNESCO, Budapest (Hungary); Tatar, Eniko [Hungarian Satellite Centre of Trace Elements Institute to UNESCO, Budapest (Hungary); L. Eoetvoes University, Department of Inorganic and Analytical Chemistry, Budapest (Hungary); Virag, Istvan [L. Eoetvoes University, Department of Inorganic and Analytical Chemistry, Budapest (Hungary); Cseh, Edit; Fodor, Ferenc [L. Eoetvoes University, Department of Plant Physiology, Budapest (Hungary); Zaray, Gyula [Joint Research Group of Environmental Chemistry of the Hungarian Academy of Sciences and L. Eoetvoes University, Budapest (Hungary); Hungarian Satellite Centre of Trace Elements Institute to UNESCO, Budapest (Hungary); L. Eoetvoes University, Department of Inorganic and Analytical Chemistry, Budapest (Hungary)

    2005-10-01

    Flow injection analysis (FIA) and high-performance liquid chromatography double-focusing sector field inductively coupled plasma mass spectrometry (HPLC-DF-ICP-MS) were used for total arsenic determination and arsenic speciation of xylem sap of cucumber plants (Cucumis sativus L.) grown in hydroponics containing 2 {mu}mol dm{sup -3} arsenate or arsenite, respectively. Arsenite [As(III)], arsenate [As(V)] and dimethylarsinic acid (DMA) were identified in the sap of the plants. Arsenite was the predominant arsenic species in the xylem saps regardless of the type of arsenic treatment, and the following concentration order was determined: As(III) > As(V) > DMA. The amount of total As, calculated taking into consideration the mass of xylem sap collected, was almost equal for both treatments. Arsenite was taken up more easily by cucumber than arsenate. Partial oxidation of arsenite to arsenate (<10% in 48 h) was observed in the case of arsenite-containing nutrient solutions, which may explain the detection of arsenate in the saps of plants treated with arsenite. (orig.)

  14. SAP and life-cycle management in the upstream

    International Nuclear Information System (INIS)

    Davis, B.

    1997-01-01

    Business relationships today depend more than ever on changing alliances and partnerships to leverage risk in a commodity market. SAP is a fully integrated, enterprise-wide software system that uses business processes tightly integrated around a common data model to facilitate these business relationships across the oil and gas supply chain. The SAP modules contain the business processes that are needed to handle the logistics and operations maintenance for operating an oil or gas field. Each industry has unique business-process requirements that the core SAP application set may not cover. In the oil and gas business, there are unique financial requirements in the upstream for working in joint ventures. In the downstream business segment, handling bulk hydrocarbons requires additional functionality

  15. Serum Amyloid P Component (SAP) Interactome in Human Plasma Containing Physiological Calcium Levels.

    Science.gov (United States)

    Poulsen, Ebbe Toftgaard; Pedersen, Kata Wolff; Marzeda, Anna Maria; Enghild, Jan J

    2017-02-14

    The pentraxin serum amyloid P component (SAP) is secreted by the liver and found in plasma at a concentration of approximately 30 mg/L. SAP is a 25 kDa homopentamer known to bind both protein and nonprotein ligands, all in a calcium-dependent manner. The function of SAP is unclear but likely involves the humoral innate immune system spanning the complement system, inflammation, and coagulation. Also, SAP is known to bind to the generic structure of amyloid deposits and possibly to protect them against proteolysis. In this study, we have characterized the SAP interactome in human plasma containing the physiological Ca 2+ concentration using SAP affinity pull-down and co-immunoprecipitation experiments followed by mass spectrometry analyses. The analyses resulted in the identification of 33 proteins, of which 24 were direct or indirect interaction partners not previously reported. The SAP interactome can be divided into categories that include apolipoproteins, the complement system, coagulation, and proteolytic regulation.

  16. CHALLENGES OF ELECTRONIC INFORMATION RESOURCES IN ...

    African Journals Online (AJOL)

    This paper discusses the role of policy for proper and efficient library services in the electronic era. It points out some of the possible dangers of embarking in electronic resources without a proper focus at hand. Thus, it calls for today's librarians and policy makers to brainstorm and come up with working policies suitable to ...

  17. Genetic evidence for the involvement of the S-layer protein gene sap and the sporulation genes spo0A, spo0B, and spo0F in Phage AP50c infection of Bacillus anthracis.

    Science.gov (United States)

    Plaut, Roger D; Beaber, John W; Zemansky, Jason; Kaur, Ajinder P; George, Matroner; Biswas, Biswajit; Henry, Matthew; Bishop-Lilly, Kimberly A; Mokashi, Vishwesh; Hannah, Ryan M; Pope, Robert K; Read, Timothy D; Stibitz, Scott; Calendar, Richard; Sozhamannan, Shanmuga

    2014-03-01

    In order to better characterize the Bacillus anthracis typing phage AP50c, we designed a genetic screen to identify its bacterial receptor. Insertions of the transposon mariner or targeted deletions of the structural gene for the S-layer protein Sap and the sporulation genes spo0A, spo0B, and spo0F in B. anthracis Sterne resulted in phage resistance with concomitant defects in phage adsorption and infectivity. Electron microscopy of bacteria incubated with AP50c revealed phage particles associated with the surface of bacilli of the Sterne strain but not with the surfaces of Δsap, Δspo0A, Δspo0B, or Δspo0F mutants. The amount of Sap in the S layer of each of the spo0 mutant strains was substantially reduced compared to that of the parent strain, and incubation of AP50c with purified recombinant Sap led to a substantial reduction in phage activity. Phylogenetic analysis based on whole-genome sequences of B. cereus sensu lato strains revealed several closely related B. cereus and B. thuringiensis strains that carry sap genes with very high similarities to the sap gene of B. anthracis. Complementation of the Δsap mutant in trans with the wild-type B. anthracis sap or the sap gene from either of two different B. cereus strains that are sensitive to AP50c infection restored phage sensitivity, and electron microscopy confirmed attachment of phage particles to the surface of each of the complemented strains. Based on these data, we postulate that Sap is involved in AP50c infectivity, most likely acting as the phage receptor, and that the spo0 genes may regulate synthesis of Sap and/or formation of the S layer.

  18. Biochemical characterization of sap (latex) of a few Indian mango varieties.

    Science.gov (United States)

    John, K Saby; Bhat, S G; Prasada Rao, U J S

    2003-01-01

    Mango sap (latex) from four Indian varieties was studied for its composition. Sap was separated into non-aqueous and aqueous phases. Earlier, we reported that the non-aqueous phase contained mainly mono-terpenes having raw mango aroma (Phytochemistry 52 (1999) 891). In the present study biochemical composition of the aqueous phase was studied. Aqueous phase contained little amount of protein (2.0-3.5 mg/ml) but showed high polyphenol oxidase (147-214 U/mg protein) and peroxidase (401-561 U/mg protein) activities. It contained low amounts of polyphenols and protease activities. On native PAGE, all the major protein bands exhibited both polyphenol oxidase and peroxidase activities. Both polyphenol oxidase and peroxidase activities were found to be stable in the aqueous phase of sap at 4 degrees C. Sap contained large amount of non-dialyzable and non-starchy carbohydrate (260-343 mg/ml sap) which may be responsible for maintaining a considerable pressure of fluid in the ducts. Thus, the mango sap could be a valuable by-product in the mango industry as it contains some of the valuable enzymes and aroma components.

  19. Implementation of SAP-IV on a minicomputer disc operating system

    International Nuclear Information System (INIS)

    Spencer, R.B.; Howard, G.E.

    1977-01-01

    The objective of the described effort was the implementation of a linear elastic finite element structural analysis program version on a minicomputer operating system while maintaining (as much as possible) the general features of the original program. SAP-IV has been successfully implemented on a minicomputer operating system as one component in a portable vibration testing, data acquisition and processing, parameter identification and design optimization system for field work. The primary features in SAP-IV facilitating conversion and implementation on a minicomputer are: (1) the calculational procedures of SAP-IV are well documented and the subroutine structure easy to follow; (2) SAP-IV is organized in a highly modular fashion; (3) it is versatile with respect to its calculational options; and (4) the element library can be readily expanded. (Auth.)

  20. Sap-Sugar Content of Grafted Sugar Maple Trees

    Science.gov (United States)

    Maurice E. Jr. Demeritt; Maurice E. Jr. Demeritt

    1985-01-01

    In March and April 1983, 289 and 196 young grafted sugar maple trees were tapped and evaluated for sap-sugar content. In April, sap was collected from taps both above and below the graft union. Diameter of all tapped trees at 18 inches above the ground was measured. Analysis of the data revealed that: (1) trees selected for high sugar yield cannot be reproduced by...

  1. Use of Electronic Resources in a Private University in Nigeria ...

    African Journals Online (AJOL)

    The study examined awareness and constraints in the use of electronic resources by lecturers and students of Ajayi Crowther University, Oyo, Nigeria. It aimed at justifying the resources expended in the provision of electronic resources in terms of awareness, patronage and factors that may be affecting awareness and use ...

  2. Electronic Resources Management System: Recommendation Report 2017

    KAUST Repository

    Ramli, Rindra M.

    2017-05-01

    This recommendation report provides an overview of the selection process for the new Electronic Resources Management System. The library has decided to move away from Innovative Interfaces Millennium ERM module. The library reviewed 3 system as potential replacements namely: Proquest 360 Resource Manager, Ex Libris Alma and Open Source CORAL ERMS. After comparing and trialling the systems, it was decided to go for Proquest 360 Resource Manager.

  3. SAP buran injury management of mangoes (mangifera indica L.) in sri lanka

    International Nuclear Information System (INIS)

    Krishnapillai, N.

    2016-01-01

    Sap burn injury is one of the major postharvest disorders that causes postharvest losses of mangoes. Popular dessert mango fruits from northern Sri Lanka were selected for this study. Mature mango fruits - Willard, Karuthakolumban, Chembaddan and Ambalavi - were harvested carefully with 5cm stalk for different treatments to minimize sap burn injury. Stalks were removed and fruits were dipped in GRAS compounds of 1 and 5% sodium chloride (Table salt) and 0.5 and 1% calcium hydroxide separately for 5 minutes. De-stemming and dipping fruits in 5% sodium chloride and 1% calcium hydroxide were effective in reducing sap burn injury in Karuthakolumban. However, 1% table salt and 0.5% calcium hydroxide successfully reduced sap burn injury in Willard, Chembaddan and Ambalavi mangoes. Fruit quality was measured in terms of pH, Total Soluble Solids (TSS) and marketability. Quality parameters of treated fruits were not significantly different (P=0.05) from non chemical treated good quality mango fruits. Sap management dynamics was very useful in controlling sap burn in Chembaddan and Ambalavi mangoes. No latex exudation was observed in these mangoes when stalk was broken by next day after harvesting. These results suggest that low cost environmentally friendly methods could be used to reduce sap burn injury in mangoes. (author)

  4. Observation of Intravascular Changes of Superabsorbent Polymer Microsphere (SAP-MS) with Monochromatic X-Ray Imaging

    International Nuclear Information System (INIS)

    Tanimoto, Daigo; Ito, Katsuyoshi; Yamamoto, Akira; Sone, Teruki; Kobatake, Makito; Tamada, Tsutomu; Umetani, Keiji

    2010-01-01

    This study was designed to evaluate the intravascular transformation behavior of superabsorbent polymer microsphere (SAP-MS) in vivo macroscopically by using monochromatic X-ray imaging and to quantitatively compare the expansion rate of SAP-MS among different kinds of mixtures. Fifteen rabbits were used for our study and transcatheter arterial embolization (TAE) was performed for their auricular arteries using monochromatic X-ray imaging. We used three kinds of SAP-MS (particle diameter 100-150 μm) mixture as embolic spherical particles: SAP-MS(H) absorbed with sodium meglumine ioxaglate (Hexabrix 320), SAP-MS(V) absorbed with isosmolar contrast medium (Visipaque 270), and SAP-MS(S) absorbed with 0.9% sodium saline. The initial volume of SAP-MS particles just after TAE and its final volume 10 minutes after TAE in the vessel were measured to calculate the expansion rate (ER) (n = 30). Intravascular behavior of SAP-MS particles was clearly observed in real time at monochromatic X-ray imaging. Averaged initial volumes of SAP-MS (H) (1.24 x 10 7 μm 3 ) were significantly smaller (p 7 μm 3 ) and SAP-MS (S) (5.85 x 10 7 μm 3 ). Averaged final volumes of SAP-MS (H) were significantly larger than averaged initial volumes (4.41 x 10 7 μm 3 vs. 1.24 x 10 7 μm 3 ; p < 0.0001, ER = 3.55). There were no significant difference between averaged final volumes and averaged initial volumes of SAP-MS (V) and SAP-MS (S). SAP-MS (H), which first travels distally, reaches to small arteries, and then expands to adapt to the vessel lumen, is an effective particle as an embolic agent, causing effective embolization.

  5. use of electronic resources by graduate students of the department

    African Journals Online (AJOL)

    respondent's access electronic resources from the internet via Cybercafé .There is a high ... KEY WORDS: Use, Electronic Resources, Graduate Students, Cybercafé. INTRODUCTION ... Faculty of Education, University of Uyo, Uyo. Olu Olat ...

  6. Influence of Auroral Streamers on Rapid Evolution of Ionospheric SAPS Flows

    Science.gov (United States)

    Gallardo-Lacourt, Bea; Nishimura, Y.; Lyons, L. R.; Mishin, E. V.; Ruohoniemi, J. M.; Donovan, E. F.; Angelopoulos, V.; Nishitani, N.

    2017-12-01

    Subauroral polarization streams (SAPS) often show large, rapid enhancements above their slowly varying component. We present simultaneous observations from ground-based all-sky imagers and flows from the Super Dual Auroral Radar Network radars to investigate the relationship between auroral phenomena and flow enhancement. We first identified auroral streamers approaching the equatorward boundary of the auroral oval to examine how often the subauroral flow increased. We also performed the reverse query starting with subauroral flow enhancements and then evaluated the auroral conditions. In the forward study, 98% of the streamers approaching the equatorward boundary were associated with SAPS flow enhancements reaching 700 m/s and typically hundreds of m/s above background speeds. The reverse study reveals that flow enhancements associated with streamers (60%) and enhanced larger-scale convection (37%) contribute to SAPS flow enhancements. The strong correlation of auroral streamers with rapid evolution (approximately minutes) of SAPS flows suggests that transient fast earthward plasma sheet flows can often lead to westward SAPS flow enhancements in the subauroral region and that such enhancements are far more common than only during substorms because of the much more frequent occurrences of streamers under various geomagnetic conditions. We also found a strong correlation between flow duration and streamer duration and a weak correlation between SAPS flow velocity and streamer intensity. This result suggests that intense flow bursts in the plasma sheet (which correlate with intense streamers) are associated with intense SAPS ionospheric flows perhaps by enhancing the ring current pressure and localized pressure gradients when they are able to penetrate close enough to Earth.

  7. Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis.

    Science.gov (United States)

    Kumar, Rohitashw; Saraswat, Darpan; Tati, Swetha; Edgerton, Mira

    2015-07-01

    Candida albicans, a commensal fungus of the oral microbiome, causes oral candidiasis in humans with localized or systemic immune deficiencies. Secreted aspartic proteinases (Saps) are a family of 10 related proteases and are virulence factors due to their proteolytic activity, as well as their roles in adherence and colonization of host tissues. We found that mice infected sublingually with C. albicans cells overexpressing Sap6 (SAP6 OE and a Δsap8 strain) had thicker fungal plaques and more severe oral infection, while infection with the Δsap6 strain was attenuated. These hypervirulent strains had highly aggregative colony structure in vitro and higher secreted proteinase activity; however, the levels of proteinase activity of C. albicans Saps did not uniformly match their abilities to damage cultured oral epithelial cells (SCC-15 cells). Hyphal induction in cells overexpressing Sap6 (SAP6 OE and Δsap8 cells) resulted in formation of large cell-cell aggregates. These aggregates could be produced in germinated wild-type cells by addition of native or heat-inactivated Sap6. Sap6 bound only to germinated cells and increased C. albicans adhesion to oral epithelial cells. The adhesion properties of Sap6 were lost upon deletion of its integrin-binding motif (RGD) and could be inhibited by addition of RGD peptide or anti-integrin antibodies. Thus, Sap6 (but not Sap5) has an alternative novel function in cell-cell aggregation, independent of its proteinase activity, to promote infection and virulence in oral candidiasis.

  8. Dynamic control of osmolality and ionic composition of the xylem sap in two mangrove species.

    Science.gov (United States)

    López-Portillo, Jorge; Ewers, Frank W; Méndez-Alonzo, Rodrigo; Paredes López, Claudia L; Angeles, Guillermo; Alarcón Jiménez, Ana Luisa; Lara-Domínguez, Ana Laura; Torres Barrera, María Del Carmen

    2014-06-01

    • Premise of the study: Xylem sap osmolality and salinity is a critical unresolved issue in plant function with impacts on transport efficiency, pressure gradients, and living cell turgor pressure, especially for halophytes such as mangrove trees.• Methods: We collected successive xylem vessel sap samples from stems and shoots of Avicennia germinans and Laguncularia racemosa using vacuum and pressure extraction and measured their osmolality. Following a series of extractions with the pressure chamber, we depressurized the shoot and pressurized again after various equilibration periods (minutes to hours) to test for dynamic control of osmolality. Transpiration and final sap osmolality were measured in shoots perfused with deionized water or different seawater dilutions.• Key results: For both species, the sap osmolality values of consecutive samples collected by vacuum extraction were stable and matched those of the initial samples extracted with the pressure chamber. Further extraction of samples with the pressure chamber decreased sap osmolality, suggesting reverse osmosis occurred. However, sap osmolalities increased when longer equilibration periods after sap extraction were allowed. Analysis of expressed sap with HPLC indicated a 1:1 relation between measured osmolality and the osmolality of the inorganic ions in the sap (mainly Na + , K + , and Cl - ), suggesting no contamination by organic compounds. In stems perfused with deionized water, the sap osmolality increased to mimic the native sap osmolality.• Conclusions: Xylem sap osmolality and ionic contents are dynamically adjusted by mangroves and may help modulate turgor pressure, hydraulic conductivity, and water potential, thus being important for mangrove physiology, survival, and distribution. © 2014 Botanical Society of America, Inc.

  9. SAP FLOW RESPONSE OF CHERRY TREES TO WEATHER CONDITION

    Directory of Open Access Journals (Sweden)

    Á. JUHÁSZ

    2011-03-01

    Full Text Available Sap flow response of cherry trees to weather condition. Themain goal of our study is to measure water-demand of cherry trees budded ontodifferent rootstocks by sapflow equipment and to study the sap flow response to themeteorological factors. The investigations are carried out in Soroksár in Hungary at‘Rita’ sweet cherry orchard. The pattern of sapflow was analyzed in relation ofsolar radiation, vapour pressure deficit and air temperature. Between solar radiationand sap flow was found a parabolic relation, daily pattern of sapflow is in closerelation (cubic also to vapour pressure deficit. No significant relationship existedbetween sapflow and air temperature. The sapflow performance of sweet cherrytrees on different rootstocks showed typical daily characters.

  10. Uncertainty in sap flow-based transpiration due to xylem properties

    Science.gov (United States)

    Looker, N. T.; Hu, J.; Martin, J. T.; Jencso, K. G.

    2014-12-01

    Transpiration, the evaporative loss of water from plants through their stomata, is a key component of the terrestrial water balance, influencing streamflow as well as regional convective systems. From a plant physiological perspective, transpiration is both a means of avoiding destructive leaf temperatures through evaporative cooling and a consequence of water loss through stomatal uptake of carbon dioxide. Despite its hydrologic and ecological significance, transpiration remains a notoriously challenging process to measure in heterogeneous landscapes. Sap flow methods, which estimate transpiration by tracking the velocity of a heat pulse emitted into the tree sap stream, have proven effective for relating transpiration dynamics to climatic variables. To scale sap flow-based transpiration from the measured domain (often area) to the whole-tree level, researchers generally assume constancy of scale factors (e.g., wood thermal diffusivity (k), radial and azimuthal distributions of sap velocity, and conducting sapwood area (As)) through time, across space, and within species. For the widely used heat-ratio sap flow method (HRM), we assessed the sensitivity of transpiration estimates to uncertainty in k (a function of wood moisture content and density) and As. A sensitivity analysis informed by distributions of wood moisture content, wood density and As sampled across a gradient of water availability indicates that uncertainty in these variables can impart substantial error when scaling sap flow measurements to the whole tree. For species with variable wood properties, the application of the HRM assuming a spatially constant k or As may systematically over- or underestimate whole-tree transpiration rates, resulting in compounded error in ecosystem-scale estimates of transpiration.

  11. Collective modes and dielectric and superconducting properties of electronic systems in confined geometries

    International Nuclear Information System (INIS)

    Ulloa, S.E.

    1984-01-01

    The dielectric response function of electronic systems in restricted geometries is studied as well as some of the consequences, using the self-consistent field method. These consequences include: 1) existence of multiple branches of longitudinal slender acoustic plasma oscillations (SAP) in thin wires; 2) a new superconductivity mechanism in thin wires via the exchange of SAPs by the electrons forming the Cooper pairs, and 3) reduction of the static screening offered by the valence electrons in a thin semiconductor film with respect to the bulk case. The SAP modes are collective modes shown to exist only in thin wires and neither in a bulk system nor in a thin film. They have linear dispersion relations with phase velocities smaller than the Fermi velocity of the system and are not Landau-damped. Numerical examples of these SAP modes in metallic and semiconductor wires are presented, showing that they sould be more easily observable in semiconductor structures. The SAP-induced mechanism of superconductivity is shown to possibly give higher critical temperature T/sub c/ than the phonon mechanism in thin wires. The author presents a semi-rigorous calculation of T/sub c/ and shows that by increasing the frequency of the SAP modes and having a small effective electron mass one would be able to increase T/sub c/. He also shows that the dielectric function of a thin semiconductor slab is wavenumber dependent even at long wavelengths and is not a constant as in the bulk case

  12. Collection and chemical composition of phloem sap from Citrus sinensis L. Osbeck (sweet orange).

    Science.gov (United States)

    Hijaz, Faraj; Killiny, Nabil

    2014-01-01

    Through utilizing the nutrient-rich phloem sap, sap feeding insects such as psyllids, leafhoppers, and aphids can transmit many phloem-restricted pathogens. On the other hand, multiplication of phloem-limited, uncultivated bacteria such as Candidatus Liberibacter asiaticus (CLas) inside the phloem of citrus indicates that the sap contains all the essential nutrients needed for the pathogen growth. The phloem sap composition of many plants has been studied; however, to our knowledge, there is no available data about citrus phloem sap. In this study, we identified and quantified the chemical components of phloem sap from pineapple sweet orange. Two approaches (EDTA enhanced exudation and centrifugation) were used to collect phloem sap. The collected sap was derivatized with methyl chloroformate (MCF), N-methyl-N- [tert-butyl dimethylsilyl]-trifluroacetamide (MTBSTFA), or trimethylsilyl (TMS) and analyzed with GC-MS revealing 20 amino acids and 8 sugars. Proline, the most abundant amino acid, composed more than 60% of the total amino acids. Tryptophan, tyrosine, leucine, isoleucine, and valine, which are considered essential for phloem sap-sucking insects, were also detected. Sucrose, glucose, fructose, and inositol were the most predominant sugars. In addition, seven organic acids including succinic, fumaric, malic, maleic, threonic, citric, and quinic were detected. All compounds detected in the EDTA-enhanced exudate were also detected in the pure phloem sap using centrifugation. The centrifugation technique allowed estimating the concentration of metabolites. This information expands our knowledge about the nutrition requirement for citrus phloem-limited bacterial pathogen and their vectors, and can help define suitable artificial media to culture them.

  13. Electronic resource management practical perspectives in a new technical services model

    CERN Document Server

    Elguindi, Anne

    2012-01-01

    A significant shift is taking place in libraries, with the purchase of e-resources accounting for the bulk of materials spending. Electronic Resource Management makes the case that technical services workflows need to make a corresponding shift toward e-centric models and highlights the increasing variety of e-formats that are forcing new developments in the field.Six chapters cover key topics, including: technical services models, both past and emerging; staffing and workflow in electronic resource management; implementation and transformation of electronic resource management systems; the ro

  14. Analysis of bleeding saps and radioactive measurements of deciduous trees

    International Nuclear Information System (INIS)

    Gomernik-Besser, E.

    1993-07-01

    Samples of bleeding sap of Betula pendula Roth, Betula lutea L., Betula papyrifera L., Betula mandshuria L., Salix melichoferi Saut., Cornus florida L., Evodea velutina L., Vitis amurensis L., Acer tartaricum L., Aesculus parviflora L., and Juglans regia L. in the botanical garden in Graz have been collected during springs of 1987, 1988, and 1989. After a special treatment (ion-exchange and freeze-drying) the bleeding saps have been searched for the compounds of sugars, amino acids and organic acids by gaschromatrography. LAMMA-spectra showed the ion composition, and radioactivity measurements on leaves of the trees have also been made. In all bleeding saps sugars could be identified in various concentrations, mainly glucose and fructose. All trees showed nearly the same acid spectrum, and the most common ingredient was malic acid. In the bleeding saps of the Betulaceae and Juglans regia the major constituent was citrulline. In Acer tartaricum allantoine was present in large concentration. In Evodea velutina, Aesculus parviflora, Vitis amurensis and Cornus florida glutamin could be identified in large concentration. After the reactor accident of Tschernobyl in April 1986 the number of synthetic radionuclides increased and they could be identified. The LAMMA-spectra showed high contents of potassium and calcium in the bleeding saps. (author)

  15. Analysis of bleeding saps and radioactive measurements of deciduous trees

    International Nuclear Information System (INIS)

    Gomernik-Besser, E.

    1993-07-01

    Samples of bleeding sap of Betula pendula Roth, Betula lutea L., Betula papyrifera L., Betula mandshuria L., Salix mielichoferi Saut., Cornus florida L., Evodea velutina L., Vitis amurensis L., Acer tartaricum L., Aesculus parviflora L., and Juglans regia L. in the botanical garden in Graz have been collected during springs of 1987, 1988, and 1989. After a special treatment (ion-exchange and freeze-drying) the bleeding saps have been searched for the compounds of sugars, amino acids and organic acids by gas-chromatrography. LAMMA-spectra showed the ion composition, and radioactivity measurements on leaves of the trees have also been made. In all bleeding saps sugars could be identified in various concentrations, mainly glucose and fructose. All trees showed nearly the same acid spectrum, and the most common ingredient was malic acid. In the bleeding saps of the Betulaceae and Juglans regia the major constituent was citrulline. In Acer tartaricum allantoine was present in large concentration. In Evodea velutina, Aesculus parviflora, Vitis amurensis and Cornus florida glutamin could be identified in large concentration. After the reactor accident of Tschernobyl in April 1986 the number of synthetic radionuclides increased and they could be identified. The LAMMA-spectra showed high contents of kalium and calcium in the bleeding saps. (author)

  16. Large-Scale Structure and Dynamics of the Sub-Auroral Polarization Stream (SAPS)

    Science.gov (United States)

    Baker, J. B. H.; Nishitani, N.; Kunduri, B.; Ruohoniemi, J. M.; Sazykin, S. Y.

    2017-12-01

    The Sub-Auroral Polarization Stream (SAPS) is a narrow channel of high-speed westward ionospheric convection which appears equatorward of the duskside auroral oval during geomagnetically active periods. SAPS is generally thought to occur when the partial ring current intensifies and enhanced region-2 field-aligned currents (FACs) are forced to close across the low conductance region of the mid-latitude ionospheric trough. However, recent studies have suggested SAPS can also occur during non-storm periods, perhaps associated with substorm activity. In this study, we used measurements from mid-latitude SuperDARN radars to examine the large-scale structure and dynamics of SAPS during several geomagnetically active days. Linear correlation analysis applied across all events suggests intensifications of the partial ring current (ASYM-H index) and auroral activity (AL index) are both important driving influences for controlling the SAPS speed. Specifically, SAPS flows increase, on average, by 20-40 m/s per 10 nT of ASYM-H and 10-30 m/s per 100 nT of AL. These dependencies tend to be stronger during the storm recovery phase. There is also a strong local time dependence such that the strength of SAPS flows decrease by 70-80 m/s for each hour of local time moving from dusk to midnight. By contrast, the evidence for direct solar wind control of SAPS speed is much less consistent, with some storms showing strong correlations with the interplanetary electric field components and/or solar wind dynamic pressure, while others do not. These results are discussed in the context of recent simulation results from the Rice Convection Model (RCM).

  17. Molecular characterization of Trypanosoma cruzi SAP proteins with host-cell lysosome exocytosis-inducing activity required for parasite invasion.

    Science.gov (United States)

    Zanforlin, Tamiris; Bayer-Santos, Ethel; Cortez, Cristian; Almeida, Igor C; Yoshida, Nobuko; da Silveira, José Franco

    2013-01-01

    To invade target cells, Trypanosoma cruzi metacyclic forms engage distinct sets of surface and secreted molecules that interact with host components. Serine-, alanine-, and proline-rich proteins (SAP) comprise a multigene family constituted of molecules with a high serine, alanine and proline residue content. SAP proteins have a central domain (SAP-CD) responsible for interaction with and invasion of mammalian cells by metacyclic forms. Using a 513 bp sequence from SAP-CD in blastn analysis, we identified 39 full-length SAP genes in the genome of T. cruzi. Although most of these genes were mapped in the T. cruzi in silico chromosome TcChr41, several SAP sequences were spread out across the genome. The level of SAP transcripts was twice as high in metacyclic forms as in epimastigotes. Monoclonal (MAb-SAP) and polyclonal (anti-SAP) antibodies produced against the recombinant protein SAP-CD were used to investigate the expression and localization of SAP proteins. MAb-SAP reacted with a 55 kDa SAP protein released by epimastigotes and metacyclic forms and with distinct sets of SAP variants expressed in amastigotes and tissue culture-derived trypomastigotes (TCTs). Anti-SAP antibodies reacted with components located in the anterior region of epimastigotes and between the nucleus and the kinetoplast in metacyclic trypomastigotes. In contrast, anti-SAP recognized surface components of amastigotes and TCTs, suggesting that SAP proteins are directed to different cellular compartments. Ten SAP peptides were identified by mass spectrometry in vesicle and soluble-protein fractions obtained from parasite conditioned medium. Using overlapping sequences from SAP-CD, we identified a 54-aa peptide (SAP-CE) that was able to induce host-cell lysosome exocytosis and inhibit parasite internalization by 52%. This study provides novel information about the genomic organization, expression and cellular localization of SAP proteins and proposes a triggering role for extracellular SAP

  18. Utilization of electronic information resources by academic staff at ...

    African Journals Online (AJOL)

    The study investigated the utilization of Electronic Information resources by the academic staff of Makerere University in Uganda. It examined the academic staff awareness of the resources available, the types of resources provided by the Makerere University Library, the factors affecting resource utilization. The study was ...

  19. Correção da acidez do solo e controle do capim-sapé Soil acidity correction and control of sapé-grass

    Directory of Open Access Journals (Sweden)

    Margarida Mesquita Carvalho

    2000-02-01

    Full Text Available RESUMO - Um experimento de campo foi realizado para verificar o efeito da correção da acidez do solo sobre o controle do capim-sapé (Imperata brasiliensis, gramínea invasora de pastagens. Pastagem de capim-gordura (Melinis minutiflora em Latossolo Vermelho-Amarelo, com intensa infestação de capim-sapé foi usada. Os tratamentos consistiram de cinco doses de calcário dolomítico (0, 1, 2, 4 e 6 t/ha, incorporado ao solo manualmente com auxílio de enxada, à profundidade de 20 cm, após gradagem das parcelas. Um tratamento extra, sem calcário e gradagem foi adotado. O delineamento experimental foi em blocos ao acaso com quatro repetições. No período de 33 meses de duração do experimento, foram feitos três cortes da vegetação aérea e duas amostragens de solo. Não houve efeito das doses de calcário sobre a produção de matéria seca do capim-sapé e das outras espécies (capim-gordura, Brachiaria decumbens e invasoras de folhas largas, apesar de terem ocorrido alterações nas características químicas do solo. A correção da acidez do solo, quando associada às correções das principais deficiências nutricionais, pode controlar o capim-sapé, ao estimular o crescimento das forrageiras.ABSTRACT - A field experiment was conducted to determine the effect of acid soil correction, on the control of the sapé (Imperata brasiliensis, a grass type weed of pasture. A molasses grass (Melinis minutiflora pasture in a red-yellow latosol, having a high proportion of "sapé" was used. Treatments consisted of five levels of dolomite limestone (0, 1, 2, 4 and 6 t/ha incorporated by hand using a garden tool to the top 20 cm of soil following a mechanical tillage of the plots (disking. An additional treatment without disking and without lime was adopted. The experimental design was randomized blocks with four replications. During the 33 months of the experimental period, three harvests and two soil samplings were performed. There were no

  20. Can Sap Flow Help Us to Better Understand Transpiration Patterns in Landscapes?

    Science.gov (United States)

    Hassler, S. K.; Weiler, M.; Blume, T.

    2017-12-01

    Transpiration is a key process in the hydrological cycle and a sound understanding and quantification of transpiration and its spatial variability is essential for management decisions and for improving the parameterisation of hydrological and soil-vegetation-atmosphere transfer models. At the tree scale, transpiration is commonly estimated by measuring sap flow. Besides evaporative demand and water availability, tree-specific characteristics such as species, size or social status, stand-specific characteristics such as basal area or stand density and site-specific characteristics such as geology, slope position or aspect control sap flow of individual trees. However, little is known about the relative importance or the dynamic interplay of these controls. We studied these influences with multiple linear regression models to explain the variability of sap velocity measurements in 61 beech and oak trees, located at 24 sites spread over a 290 km²-catchment in Luxembourg. For each of 132 consecutive days of the growing season of 2014 we applied linear models to the daily spatial pattern of sap velocity and determined the importance of the different predictors. By upscaling sap velocities to the tree level with the help of species-dependent empirical estimates for sapwood area we also examined patterns of sap flow as a more direct representation of transpiration. Results indicate that a combination of mainly tree- and site-specific factors controls sap velocity patterns in this landscape, namely tree species, tree diameter, geology and aspect. For sap flow, the site-specific predictors provided the largest contribution to the explained variance, however, in contrast to the sap velocity analysis, geology was more important than aspect. Spatial variability of atmospheric demand and soil moisture explained only a small fraction of the variance. However, the temporal dynamics of the explanatory power of the tree-specific characteristics, especially species, were

  1. Electronic Resources Management Project Presentation 2012

    KAUST Repository

    Ramli, Rindra M.

    2012-01-01

    This presentation describes the electronic resources management project undertaken by the KAUST library. The objectives of this project is to migrate information from MS Sharepoint to Millennium ERM module. One of the advantages of this migration

  2. Strategic Alliance Poker: Demonstrating the Importance of Complementary Resources and Trust in Strategic Alliance Management

    Science.gov (United States)

    Reutzel, Christopher R.; Worthington, William J.; Collins, Jamie D.

    2012-01-01

    Strategic Alliance Poker (SAP) provides instructors with an opportunity to integrate the resource based view with their discussion of strategic alliances in undergraduate Strategic Management courses. Specifically, SAP provides Strategic Management instructors with an experiential exercise that can be used to illustrate the value creation…

  3. Phosphorylated SAP155, the spliceosomal component, is localized to chromatin in postnatal mouse testes

    Energy Technology Data Exchange (ETDEWEB)

    Eto, Ko, E-mail: etoko@gpo.kumamoto-u.ac.jp [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555 (Japan); Sonoda, Yoshiyuki [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555 (Japan); Jin, Yuji [School of Basic Medicine, Jilin Medical College, Jilin 132013 (China); Abe, Shin-ichi [Department of Biological Sciences, Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555 (Japan)

    2010-03-19

    SAP155 is an essential component of the spliceosome and its phosphorylation is required for splicing catalysis, but little is known concerning its expression and regulation during spermatogenesis in postnatal mouse testes. We report that SAP155 is ubiquitously expressed in nuclei of germ and Sertoli cells within the seminiferous tubules of 6- and 35-day postpartum (dpp) testes. Analyses by fractionation of testes revealed that (1) phosphorylated SAP155 was found in the fraction containing nuclear structures at 6 dpp in amounts much larger than that at other ages; (2) non-phosphorylated SAP155 was detected in the fraction containing nucleoplasm; and (3) phosphorylated SAP155 was preferentially associated with chromatin. Our findings suggest that the active spliceosome, containing phosphorylated SAP155, performs pre-mRNA splicing on chromatin concomitant with transcription during testicular development.

  4. Implementation of SAP-IV on a minicomputer disc operating system

    International Nuclear Information System (INIS)

    Spencer, R.B.; Howard, G.E.

    1977-01-01

    The objective of the described effort was the implementation of a linear elastic finite element structural analysis program version on a minicomputer operating system while maintaining (as much as possible) the general features of the original program. SAP-IV has been successfully implemented on a minicomputer operating system as one component in a portable vibration testing, data acquisition and processing, parameter identification and design optimization system for field work. The primary features in SAP-IV facilitating conversion and implementation on a minicomputer are: (1) the calculational procedures of SAP-IV are well documented and the subroutine structure easy to follow; (2) SAP-IV is organized in a highly modular fashion; (3) it is versatile with respect to its calculational options; and (4) the element library can be readily expanded. SAP-IV was installed on a Data General NOVA 32K memory disc operating system which utilizes various input-output peripherals and a single 1.2 megaword disc. The entire theoretical analysis-vibration test-data analysis-parameter identification-model modification system required such additional components as analog/digital converters, computer-driven electro-mechanical vibrators, a maximum of 512 transducers, and special-purpose software for test planning, execution, data processing, and matrix manipulation. The software system capabilities which allowed implementation of SAP-IV on the minicomputer were: (1) the availability of double precision; (2) the ability to use multiple OVERLAYs; (3) the ability to read and write programs from the disc to memory without destroying the programs (SWAP); (4) the ability to CHAIN a series of connected programs into the memory and execute them sequentially; and (5) the ability to utilize random access disc files

  5. From Sap to Syrup

    Science.gov (United States)

    Bjork, Janna

    2005-01-01

    Warm days, cold nights, melting snow-signs winter is waning and spring is nearing. Though winter may just be getting started in some areas, it's always fun to appreciate the good things about winter, including the special time at the end of winter in New England known as "sugaring time." The sap starts flowing in the sugar maples, and…

  6. Stabilization/Solidification of Radioactive LiCl-KCl Waste Salt by Using SiO2-Al2O3-P2O5(SAP) Inorganic Composite: Part 2. The Effect of SAP Composition on Stabilization/Solidification

    International Nuclear Information System (INIS)

    Ahn, Soo Na; Park, Hwan Seo; Cho, In Hak; Kim, In Tae; Cho, Yong Zun

    2012-01-01

    Metal chloride waste is generated as a main waste streams in a series of electrolytic processes of a pyrochemical process. Different from carbonate or nitrate salt, metal chloride is not decomposed into oxide and chlorine but it is just vaporized. Also, it has low compatibility with conventional silicate glasses. Our research group adapted the dechlorination approach for the immobilization of waste salt. In this study, the composition of SAP (SiO 2 -Al 2 O 3 -P 2 O 5 ) was adjusted to enhance the reactivity and to simplify the solidification process as a subsequent research. The addition of Fe 2 O 3 into the basic SAP decreased the SAP/Salt ratio in weight from 3 for SAP 1071 to 2.25 for M-SAP(Fe=0.1). The experimental results indicated that the addition of Fe 2 O 3 increased the reactivity of M-SAP with LiCl-KCl but the reactivity gradually decreased above Fe=0.1. Also, introducing B 2 O 3 into M-SAP requires no glass binder for the consolidation of reaction products. U-SAP (SiO 2 -Al 2 O 3 -P 2 O 5 ) could effectively dechlorinate the LiCl-KCl waste and its reaction product could be consolidated as a monolithic form without a glass binder. The leaching test result indicated that U-SAP 1071 was more durable than other SAPs wasteform. By using U-SAP, 1 g of waste salt could generated 3 - 4 g of wasteform for final disposal. The final volume would be about 3 - 4 times lower than the glass-bonded sodalite. From these results, it could be concluded that the dechlorination approach using U-SAP would be one of prospective methods to manage the volatile waste salt.

  7. Evaluasi Implementasi SAP Modul Material Management: Studi Kasus pada PT Bumitama Gunajaya Agro

    Directory of Open Access Journals (Sweden)

    Santo Fernandi Wijaya

    2012-06-01

    Full Text Available An integrated information system is a necessity for a company to help solve problems in business transactions management. SAP application is an application that is able to provide solutions to such problems. The purpose of this study was to evaluate the running business processes on the Material Management module;evaluate the performance of the running SAP systems associated with the implementation and maintenance of SAP applications as well as to give sugestions based on the development of evaluation results obtained, in terms of business processes, performance, and financial. Utilized for analysis is IT Balanced Scorecard method, while ASAP (Accelerated SAP method is used for the system development. This study produced an analysis of the evaluation of the enterprise business processes in implementing the SAP development of ERP system modulesMaterial Management.

  8. Subauroral Polarization Streams (SAPS) Duration as Determined From Van Allen Probe Successive Electric Drift Measurements

    Science.gov (United States)

    Lejosne, Solène; Mozer, F. S.

    2017-09-01

    We examine a characteristic feature of the magnetosphere-ionosphere coupling, namely, the persistent and latitudinally narrow bands of rapid westward ion drifts called the subauroral polarization streams (SAPS). Despite countless works on SAPS, information relative to their durations is lacking. Here we report on the first statistical analysis of more than 200 near-equatorial SAPS observations based on more than 2 years of Van Allen Probe electric drift measurements. First, we present results relative to SAPS radial locations and amplitudes. Then, we introduce two different ways to estimate SAPS durations. In both cases, SAPS activity is estimated to last for about 9 h on average. However, our estimates for SAPS duration are limited either by the relatively long orbital periods of the spacecraft or by the relatively small number of observations involved. Fifty percent of the events fit within the time interval [0;18] hours.

  9. Sap Flux Scaled Transpiration in Ring-porous Tree Species: Assumptions, Pitfalls and Calibration

    Science.gov (United States)

    Bush, S. E.; Hultine, K. R.; Ehleringer, J. R.

    2008-12-01

    Thermal dissipation probes for measuring sap flow (Granier-type) at the whole tree and stand level are routinely used in forest ecology and site water balance studies. While the original empirical relationship used to calculate sap flow was reported as independent of wood anatomy (ring-porous, diffuse-porous, tracheid), it has been suggested that potentially large errors in sap flow calculations may occur when using the original calibration for ring-porous species, due to large radial trends in sap velocity and/or shallow sapwood depth. Despite these concerns, sap flux measurements have rarely been calibrated in ring-porous taxa. We used a simple technique to calibrate thermal dissipation sap flux measurements on ring-porous trees in the lab. Calibration measurements were conducted on five ring-porous species in the Salt Lake City, USA metropolitan area including Quercus gambelii (Gambel oak), Gleditsia triacanthos (Honey locust), Elaeagnus angustifolia (Russian olive), Sophora japonica (Japanese pagoda), and Celtis occidentalis (Common hackberry). Six stems per species of approximately 1 m in length were instrumented with heat dissipation probes to measure sap flux concurrently with gravimetric measurements of water flow through each stem. Safranin dye was pulled through the stems following flow rate measurements to determine sapwood area. As expected, nearly all the conducting sapwood area was limited to regions within the current year growth rings. Consequently, we found that the original Granier equation underestimated sap flux density for all species considered. Our results indicate that the use of thermal dissipation probes for measuring sap flow in ring-porous species should be independently calibrated, particularly when species- specific calibration data are not available. Ring-porous taxa are widely distributed and represent an important component of the regional water budgets of many temperate regions. Our results are important for evaluating plant water

  10. Practical guide to electronic resources in the humanities

    CERN Document Server

    Dubnjakovic, Ana

    2010-01-01

    From full-text article databases to digitized collections of primary source materials, newly emerging electronic resources have radically impacted how research in the humanities is conducted and discovered. This book, covering high-quality, up-to-date electronic resources for the humanities, is an easy-to-use annotated guide for the librarian, student, and scholar alike. It covers online databases, indexes, archives, and many other critical tools in key humanities disciplines including philosophy, religion, languages and literature, and performing and visual arts. Succinct overviews of key eme

  11. Constituents and Antioxidant Activity of Bleeding Sap from Various Xinjiang Grapes.

    Science.gov (United States)

    Le, Lv; Umar, Anwar; Iburaim, Arkin; Moore, Nicholas

    2017-10-01

    Wine grape sap or bleeding sap of grapes (GBS) is commonly used in Xinjiang (China) for therapeutic aims. Do variations in composition related to region and variety affect its properties? GBS samples originating in various parts of Xinjiang (Turpan, Hotan, Kashgar, and Atush) were tested for phenols and polyphenols, polysaccharides, saponin, proteins, individual amino acids, and minerals. Their antioxidant activity was measured using ascorbic acid as reference. Polyphenol content varied from 2.6 to 6.6 mg/L, polysaccharides 18.3-816 mg/L, saponin 6.25-106 mg/L, and protein 3.0-22.4 mg/L. Mineral elements and amino acids ranged from 6.20 to 201.2 mg/L and 0.06-118.7 mg/L, respectively. ·OH scavenging ability varied from 70% to over 90%, higher than Vitamin C. Grapes from Turpan had lower antioxidant activity than other grapes even though the polyphenol content was generally higher. Bleeding sap of Xinjiang grape is rich in amino acids, polysaccharides, polyphenols, and protein. The contents are different according to the origin, related possibly to species, climate, and environment. Antioxidant effects were not correlated with polyphenol content. Antioxidant activity of plants or plant extracts is often associated with polyphenolsBleeding sap of grapes has strong antioxidant propertiesBleeding sap from different grape varieties from different parts of Xinjiang (China) had different polyphenol concentrationsThere was no correlation of polyphenol concentrations with antioxidant activity. Abbreviations used: GBS: Bleeding sap of grapes; PITC: phenyl isothiocyanate.

  12. SAPFLUXNET: towards a global database of sap flow measurements.

    Science.gov (United States)

    Poyatos, Rafael; Granda, Víctor; Molowny-Horas, Roberto; Mencuccini, Maurizio; Steppe, Kathy; Martínez-Vilalta, Jordi

    2016-12-01

    Plant transpiration is the main evaporative flux from terrestrial ecosystems; it controls land surface energy balance, determines catchment hydrological responses and influences regional and global climate. Transpiration regulation by plants is a key (and still not completely understood) process that underlies vegetation drought responses and land evaporative fluxes under global change scenarios. Thermometric methods of sap flow measurement have now been widely used to quantify whole-plant and stand transpiration in forests, shrublands and orchards around the world. A large body of research has applied sap flow methods to analyse seasonal and diurnal patterns of transpiration and to quantify their responses to hydroclimatic variability, but syntheses of sap flow data at regional to global scales are extremely rare. Here we present the SAPFLUXNET initiative, aimed at building the first global database of plant-level sap flow measurements. A preliminary metadata survey launched in December 2015 showed an encouraging response by the sap flow community, with sap flow data sets from field studies representing >160 species and >120 globally distributed sites. The main goal of SAPFLUXNET is to analyse the ecological factors driving plant- and stand-level transpiration. SAPFLUXNET will open promising research avenues at an unprecedented global scope, namely: (i) exploring the spatio-temporal variability of plant transpiration and its relationship with plant and stand attributes, (ii) summarizing physiological regulation of transpiration by means of few water-use traits, usable for land surface models, (iii) improving our understanding of the coordination between gas exchange and plant-level traits (e.g., hydraulics) and (iv) analysing the ecological factors controlling stand transpiration and evapotranspiration partitioning. Finally, SAPFLUXNET can provide a benchmark to test models of physiological controls of transpiration, contributing to improve the accuracy of

  13. Microscopic insight into thermodynamics of conformational changes of SAP-SLAM complex in signal transduction cascade

    Science.gov (United States)

    Samanta, Sudipta; Mukherjee, Sanchita

    2017-04-01

    The signalling lymphocytic activation molecule (SLAM) family of receptors, expressed by an array of immune cells, associate with SLAM-associated protein (SAP)-related molecules, composed of single SH2 domain architecture. SAP activates Src-family kinase Fyn after SLAM ligation, resulting in a SLAM-SAP-Fyn complex, where, SAP binds the Fyn SH3 domain that does not involve canonical SH3 or SH2 interactions. This demands insight into this SAP mediated signalling cascade. Thermodynamics of the conformational changes are extracted from the histograms of dihedral angles obtained from the all-atom molecular dynamics simulations of this structurally well characterized SAP-SLAM complex. The results incorporate the binding induced thermodynamic changes of individual amino acid as well as the secondary structural elements of the protein and the solvent. Stabilization of the peptide partially comes through a strong hydrogen bonding network with the protein, while hydrophobic interactions also play a significant role where the peptide inserts itself into a hydrophobic cavity of the protein. SLAM binding widens SAP's second binding site for Fyn, which is the next step in the signal transduction cascade. The higher stabilization and less fluctuation of specific residues of SAP in the Fyn binding site, induced by SAP-SLAM complexation, emerge as the key structural elements to trigger the recognition of SAP by the SH3 domain of Fyn. The thermodynamic quantification of the protein due to complexation not only throws deeper understanding in the established mode of SAP-SLAM interaction but also assists in the recognition of the relevant residues of the protein responsible for alterations in its activity.

  14. Inner strategies of coping with operational work amongst SAPS officers

    Directory of Open Access Journals (Sweden)

    Masefako A. Gumani

    2013-11-01

    Research purpose: The objective of this study was to describe inner coping strategies used by officers in the Vhembe district (South Africa to reconstruct stressful and traumatic experiences at work. Motivation for the study: Most studies on coping amongst SAPS officers focus on organisational stress and not on the impact of the officers’ operational work. Research design, approach and method: An exploratory design was used and 20 SAPS officers were selected through purposive sampling. In-depth face-to-face and telephone interviews, as well as diaries were used to collect data, which were analysed using content thematic data analysis. Main findings: The results showed that the main categories of coping strategies that led to management of the impact of operational work amongst the selected sample were centred around problem-focused and emotion-focused strategies, with some use of reappraisal and minimal use of avoidance. Considering the context of the officers’ work, the list of dimensions of inner coping strategies amongst SAPS officers should be extended. Practical/managerial implications: Intervention programmes designed for the SAPS, including critical incident stress debriefing, should take the operational officers’ inner strategies into account to improve the management of the impact of their work. Contribution/value-add: This study contributes to the body of knowledge on the inner coping strategies amongst SAPS officers, with special reference to operational work in a specific setting.

  15. Studi Kelayakan Implementasi SAP dengan Metode Fit/Gap Analysis dan CBA

    Directory of Open Access Journals (Sweden)

    Nurlina Nurlina

    2013-12-01

    Full Text Available An application system is required by a company to meet the needs of enterprise business processes so as to provide information quickly and accurately. Therefore, it is necessary to study the feasibility status of plan of enterprise system implementation. SAP R/3 contains various modules which is deserved to be considered as a company's information system solution. Results of the feasibility study through the analysis of fit/ gap analysis state that the implementation of SAP R/3 sales module is feasible and able to meet all the needs of the system.Results of cost and benefit analysis state that the strategy implementation of SAP R/3 module is feasible. Based on the analysis and research using the two methods above, a decision can be taken whether the SAP R/3 is worth to be implemented or not.

  16. Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7

    International Nuclear Information System (INIS)

    Hu, Dong; Wu, Jing; Wang, Wan; Mu, Min; Zhao, Runpeng; Xu, Xuewei; Chen, Zhaoquan; Xiao, Jian; Hu, Fengyu; Yang, Yabo; Zhang, Rongbo

    2015-01-01

    The mechanism underlying autophagy alteration by mycobacterium tuberculosis remains unclear. Our previous study shows LpqH, a lipoprotein of mycobacterium tuberculosis, can cause autophagosomes accumulation in murine macrophages. It is well known that SapM, another virulence factor, plays an important role in blocking phagosome-endosome fusion. However, the mechanism that SapM interferes with autophagy remains poorly defined. In this study, we report that SapM suppresses the autophagy flux by blocking autophagosome fusion with lysosome. Exposure to SapM results in accumulations of autophagosomes and decreased co-localization of autophagosome with lysosome. Molecularly, Rab7, a small GTPase, is blocked by SapM through its CT domain and is prevented from involvement of autophagosome-lysosome fusion. In conclusion, our study reveals that SapM takes Rab7 as a previously unknown target to govern a distinct molecular mechanism underlying autophagosome-lysosome fusion, which may bring light to a new thought about developing potential drugs or vaccines against tuberculosis. - Highlights: • A mechanism for disrupting autophagosome-lysosome fusion induced by SapM. • Rab7 is involved in SapM-inhibited autophagy. • SapM interacts with Rab7 by CT-domain. • CT-domain is indispensable to SapM-inhibited autophagy

  17. Autophagy regulation revealed by SapM-induced block of autophagosome-lysosome fusion via binding RAB7

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Dong, E-mail: austhudong@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Wu, Jing, E-mail: wujing8008@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Wang, Wan; Mu, Min; Zhao, Runpeng; Xu, Xuewei; Chen, Zhaoquan [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China); Xiao, Jian [School of Pharmacy, Wenzhou Medical College, Wenzhou (China); Hu, Fengyu; Yang, Yabo [Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou (China); Zhang, Rongbo, E-mail: lory456@126.com [Institute of Infection and Immunology, Department of Medical Immunology, Medical School, Anhui University of Science and Technology, Huainan (China)

    2015-05-29

    The mechanism underlying autophagy alteration by mycobacterium tuberculosis remains unclear. Our previous study shows LpqH, a lipoprotein of mycobacterium tuberculosis, can cause autophagosomes accumulation in murine macrophages. It is well known that SapM, another virulence factor, plays an important role in blocking phagosome-endosome fusion. However, the mechanism that SapM interferes with autophagy remains poorly defined. In this study, we report that SapM suppresses the autophagy flux by blocking autophagosome fusion with lysosome. Exposure to SapM results in accumulations of autophagosomes and decreased co-localization of autophagosome with lysosome. Molecularly, Rab7, a small GTPase, is blocked by SapM through its CT domain and is prevented from involvement of autophagosome-lysosome fusion. In conclusion, our study reveals that SapM takes Rab7 as a previously unknown target to govern a distinct molecular mechanism underlying autophagosome-lysosome fusion, which may bring light to a new thought about developing potential drugs or vaccines against tuberculosis. - Highlights: • A mechanism for disrupting autophagosome-lysosome fusion induced by SapM. • Rab7 is involved in SapM-inhibited autophagy. • SapM interacts with Rab7 by CT-domain. • CT-domain is indispensable to SapM-inhibited autophagy.

  18. Utilisation of Electronic Information Resources By Lecturers in ...

    African Journals Online (AJOL)

    This study assesses the use of information resources, specifically, electronic databases by lecturers/teachers in Universities and Colleges of Education in South Western Nigeria. Information resources are central to teachers' education. It provides lecturers/teachers access to information that enhances research and ...

  19. SAP-like domain in nucleolar spindle associated protein mediates mitotic chromosome loading as well as interphase chromatin interaction

    Energy Technology Data Exchange (ETDEWEB)

    Verbakel, Werner, E-mail: werner.verbakel@chem.kuleuven.be [Laboratory of Biomolecular Dynamics, Katholieke Universiteit Leuven, Celestijnenlaan 200G, Bus 2403, 3001 Heverlee (Belgium); Carmeliet, Geert, E-mail: geert.carmeliet@med.kuleuven.be [Laboratory of Experimental Medicine and Endocrinology, Katholieke Universiteit Leuven, Herestraat 49, Bus 902, 3000 Leuven (Belgium); Engelborghs, Yves, E-mail: yves.engelborghs@fys.kuleuven.be [Laboratory of Biomolecular Dynamics, Katholieke Universiteit Leuven, Celestijnenlaan 200G, Bus 2403, 3001 Heverlee (Belgium)

    2011-08-12

    Highlights: {yields} The SAP-like domain in NuSAP is a functional DNA-binding domain with preference for dsDNA. {yields} This SAP-like domain is essential for chromosome loading during early mitosis. {yields} NuSAP is highly dynamic on mitotic chromatin, as evident from photobleaching experiments. {yields} The SAP-like domain also mediates NuSAP-chromatin interaction in interphase nucleoplasm. -- Abstract: Nucleolar spindle associated protein (NuSAP) is a microtubule-stabilizing protein that localizes to chromosome arms and chromosome-proximal microtubules during mitosis and to the nucleus, with enrichment in the nucleoli, during interphase. The critical function of NuSAP is underscored by the finding that its depletion in HeLa cells results in various mitotic defects. Moreover, NuSAP is found overexpressed in multiple cancers and its expression levels often correlate with the aggressiveness of cancer. Due to its localization on chromosome arms and combination of microtubule-stabilizing and DNA-binding properties, NuSAP takes a special place within the extensive group of spindle assembly factors. In this study, we identify a SAP-like domain that shows DNA binding in vitro with a preference for dsDNA. Deletion of the SAP-like domain abolishes chromosome arm binding of NuSAP during mitosis, but is not sufficient to abrogate its chromosome-proximal localization after anaphase onset. Fluorescence recovery after photobleaching experiments revealed the highly dynamic nature of this NuSAP-chromatin interaction during mitosis. In interphase cells, NuSAP also interacts with chromatin through its SAP-like domain, as evident from its enrichment on dense chromatin regions and intranuclear mobility, measured by fluorescence correlation spectroscopy. The obtained results are in agreement with a model where NuSAP dynamically stabilizes newly formed microtubules on mitotic chromosomes to enhance chromosome positioning without immobilizing these microtubules. Interphase NuSAP

  20. SAP-like domain in nucleolar spindle associated protein mediates mitotic chromosome loading as well as interphase chromatin interaction

    International Nuclear Information System (INIS)

    Verbakel, Werner; Carmeliet, Geert; Engelborghs, Yves

    2011-01-01

    Highlights: → The SAP-like domain in NuSAP is a functional DNA-binding domain with preference for dsDNA. → This SAP-like domain is essential for chromosome loading during early mitosis. → NuSAP is highly dynamic on mitotic chromatin, as evident from photobleaching experiments. → The SAP-like domain also mediates NuSAP-chromatin interaction in interphase nucleoplasm. -- Abstract: Nucleolar spindle associated protein (NuSAP) is a microtubule-stabilizing protein that localizes to chromosome arms and chromosome-proximal microtubules during mitosis and to the nucleus, with enrichment in the nucleoli, during interphase. The critical function of NuSAP is underscored by the finding that its depletion in HeLa cells results in various mitotic defects. Moreover, NuSAP is found overexpressed in multiple cancers and its expression levels often correlate with the aggressiveness of cancer. Due to its localization on chromosome arms and combination of microtubule-stabilizing and DNA-binding properties, NuSAP takes a special place within the extensive group of spindle assembly factors. In this study, we identify a SAP-like domain that shows DNA binding in vitro with a preference for dsDNA. Deletion of the SAP-like domain abolishes chromosome arm binding of NuSAP during mitosis, but is not sufficient to abrogate its chromosome-proximal localization after anaphase onset. Fluorescence recovery after photobleaching experiments revealed the highly dynamic nature of this NuSAP-chromatin interaction during mitosis. In interphase cells, NuSAP also interacts with chromatin through its SAP-like domain, as evident from its enrichment on dense chromatin regions and intranuclear mobility, measured by fluorescence correlation spectroscopy. The obtained results are in agreement with a model where NuSAP dynamically stabilizes newly formed microtubules on mitotic chromosomes to enhance chromosome positioning without immobilizing these microtubules. Interphase NuSAP-chromatin interaction

  1. Spatial and temporal variations in sap flux density in Japanese cedar (Cryptomeria japonica) trees, central Taiwan

    Science.gov (United States)

    Tseng, Han; Chiu, Chen-Wei; Wey, Tsong-Huei; Kume, Tomonori

    2013-04-01

    Sap flow measurement method is a technique widely used for measuring forest transpiration. However, variations in sap flow distribution can make accurately estimating individual tree-scale transpiration difficult. Significant spatial variations in sap flow across the sapwood within tree have been reported in many studies. In contrast, few studies have discussed azimuthal variations in sap flow, and even fewer have examined their seasonal change characteristics. This study was undertaken to clarify within-tree special and temporal variations in sap flow, and to propose an appropriate design for individual-tree scale transpiration estimates for Japanese cedar trees. The measurement was conducted in a Japanese cedar plantation located in Central Taiwan. Spatial distribution of sap flux density through the sapwood cross-section was measured using Granier's thermal dissipation technique. Sensors were installed at 1.3 m high on the east, west, north and south sides of the stem at 0-2 cm in 8 trees, and at 2-4 cm in the 6 larger trees. We found, in radial profile analysis, that sap flux densities measured at the depth of 2-4 cm were 50 % in average of those measured at depth of 0-2 cm. In azimuthal profile analysis, we found significant azimuthal variations in sap flux density. In one individual tree, the ratio of sap flux density on one aspect to another could be approximately 40-190 %, with no dependency on directions. Both radial and azimuthal profiles in most sample trees were fairly consistent throughout the measurement period. We concluded that radial and azimuthal variations in sap flow across sapwood might introduce significant errors in individual tree-scale transpiration estimations based on single point sap flow measurement, and seasonal change of within-tree spatial variations in sap flow could have insignificant impacts on accuracy of long-term individual tree-scale transpiration estimates. Keywords: transpiration, sap flow measurement, scaling up, sap flow

  2. Managing the Technology Acquisition Integration Paradox at SAP

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Kude, Thomas; Popp, Karl Michael

    2016-01-01

    rests in ensuring critical speed while not compromising accuracy in the integration process. For SAP, the Product Council became a vital component in its technology acquisition capability that allows the company to retain its technological edge in the hypercompetitive software industry.......In this paper, we report on a novel approach developed by SAP AG, the German enterprise software company, for managing the integration of acquisitions of companies to access innovative technologies and related capabilities: the Product Council approach. The value of the Product Council approach...

  3. Discipline, availability of electronic resources and the use of Finnish National Electronic Library - FinELib

    Directory of Open Access Journals (Sweden)

    Sanna Torma

    2004-01-01

    Full Text Available This study elaborated relations between digital library use by university faculty, users' discipline and the availability of key resources in the Finnish National Electronic Library (FinELib, Finnish national digital library, by using nationwide representative survey data. The results show that the perceived availability of key electronic resources by researchers in FinELib was a stronger predictor of the frequency and purpose of use of its services than users' discipline. Regardless of discipline a good perceived provision of central resources led to a more frequent use of FinELib. The satisfaction with the services did not vary with the discipline, but with the perceived availability of resources.

  4. Implementace modulu řízení lidstkých zdrojů systému SAP

    OpenAIRE

    Kroupa, Filip

    2009-01-01

    This thesis is focused on implementation of SAP ERP system, specifically its human capital management module (HCM), in a real organization. Its goal is to describe problems this organization had to face and suggest improvements so that these problems would not repeat. In the first part of the thesis, author gives an introduction to human resources and time management of the employees (attendances, absences etc.). The role of HR department in the organization, its evolution and tasks, and how ...

  5. The Role of the Acquisitions Librarian in Electronic Resources Management

    Science.gov (United States)

    Pomerantz, Sarah B.

    2010-01-01

    With the ongoing shift to electronic formats for library resources, acquisitions librarians, like the rest of the profession, must adapt to the rapidly changing landscape of electronic resources by keeping up with trends and mastering new skills related to digital publishing, technology, and licensing. The author sought to know what roles…

  6. Verification of SAP reference models

    NARCIS (Netherlands)

    Dongen, van B.F.; Jansen-Vullers, M.H.; Aalst, van der W.M.P.; Benatallah, B.; Casati, F.

    2005-01-01

    To configure a process-aware information system (e.g., a workflow system, an ERP system), a business model needs to be transformed into an executable process model. Due to similarities in these transformations for different companies, databases with reference models, such as ARIS for MySAP, have

  7. Analysis of Pedagogic Potential of Electronic Educational Resources with Elements of Autodidactics

    Directory of Open Access Journals (Sweden)

    Igor A.

    2018-03-01

    Full Text Available Introduction: in recent years didactic properties of electronic educational resources undergo considerable changes, nevertheless, the question of studying of such complete phenomenon as “an electronic educational resource with autodidactics elements” remains open, despite sufficient scientific base of researches of the terms making this concept. Article purpose – determination of essence of electronic educational resources with autodidactics elements. Materials and Methods: the main method of research was the theoretical analysis of the pedagogical and psychological literature on the problem under study. We used the theoretical (analysis, synthesis, comparison and generalization methods, the method of interpretation, pedagogical modeling, and empirical methods (observation, testing, conversation, interview, analysis of students’ performance, pedagogical experiment, peer review. Results: we detected the advantages of electronic educational resources in comparison with traditional ones. The concept of autodidactics as applied to the subject of research is considered. Properties of electronic educational resources with a linear and nonlinear principle of construction are studied.The influence of the principle of construction on the development of the learners’ qualities is shown. We formulated an integral definition of electronic educational resources with elements of autodidactics, namely, the variability, adaptivity and cyclicity of training. A model of the teaching-learning process with electronic educational resources is developed. Discussion and Conclusions: further development of a problem will allow to define whether electronic educational resources with autodidactics elements pedagogical potential for realization of educational and self-educational activity of teachers have, to modify technological procedures taking into account age features of students, their specialties and features of the organization of process of training of

  8. Preservation and conservation of electronic information resources of ...

    African Journals Online (AJOL)

    The major holdings of the broadcast libraries of the Nigerian Television Authority (NTA) are electronic information resources; therefore, providing safe places for general management of these resources have aroused interest in the industry in Nigeria for sometimes. The need to study the preservation and conservation of ...

  9. Water Use Patterns of Four Tropical Bamboo Species Assessed with Sap Flux Measurements.

    Science.gov (United States)

    Mei, Tingting; Fang, Dongming; Röll, Alexander; Niu, Furong; Hendrayanto; Hölscher, Dirk

    2015-01-01

    Bamboos are grasses (Poaceae) that are widespread in tropical and subtropical regions. We aimed at exploring water use patterns of four tropical bamboo species (Bambusa vulgaris, Dendrocalamus asper, Gigantochloa atroviolacea, and G. apus) with sap flux measurement techniques. Our approach included three experimental steps: (1) a pot experiment with a comparison of thermal dissipation probes (TDPs), the stem heat balance (SHB) method and gravimetric readings using potted B. vulgaris culms, (2) an in situ calibration of TDPs with the SHB method for the four bamboo species, and (3) field monitoring of sap flux of the four bamboo species along with three tropical tree species (Gmelina arborea, Shorea leprosula, and Hevea brasiliensis) during a dry and a wet period. In the pot experiment, it was confirmed that the SHB method is well suited for bamboos but that TDPs need to be calibrated. In situ, species-specific parameters for such calibration formulas were derived. During field monitoring we found that some bamboo species reached high maximum sap flux densities. Across bamboo species, maximal sap flux density increased with decreasing culm diameter. In the diurnal course, sap flux densities in bamboos peaked much earlier than radiation and vapor pressure deficit (VPD), and also much earlier than sap flux densities in trees. There was a pronounced hysteresis between sap flux density and VPD in bamboos, which was less pronounced in trees. Three of the four bamboo species showed reduced sap flux densities at high VPD values during the dry period, which was associated with a decrease in soil moisture content. Possible roles of internal water storage, root pressure and stomatal sensitivity are discussed.

  10. Phrenic long-term facilitation following intrapleural CTB-SAP-induced respiratory motor neuron death.

    Science.gov (United States)

    Nichols, Nicole L; Craig, Taylor A; Tanner, Miles A

    2017-08-16

    Amyotrophic lateral sclerosis (ALS) is a devastating disease leading to progressive motor neuron degeneration and death by ventilatory failure. In a rat model of ALS (SOD1 G93A ), phrenic long-term facilitation (pLTF) following acute intermittent hypoxia (AIH) is enhanced greater than expected at disease end-stage but the mechanism is unknown. We suggest that one trigger for this enhancement is motor neuron death itself. Intrapleural injections of cholera toxin B fragment conjugated to saporin (CTB-SAP) selectively kill respiratory motor neurons and mimic motor neuron death observed in SOD1 G93A rats. This CTB-SAP model allows us to study the impact of respiratory motor neuron death on breathing without many complications attendant to ALS. Here, we tested the hypothesis that phrenic motor neuron death is sufficient to enhance pLTF. pLTF was assessed in anesthetized, paralyzed and ventilated Sprague Dawley rats 7 and 28days following bilateral intrapleural injections of: 1) CTB-SAP (25μg), or 2) un-conjugated CTB and SAP (control). CTB-SAP enhanced pLTF at 7 (CTB-SAP: 162±18%, n=8 vs. 63±3%; n=8; pSAP: 64±10%, n=10 vs. 60±13; n=8; p>0.05). Thus, pLTF at 7 (not 28) days post-CTB-SAP closely resembles pLTF in end-stage ALS rats, suggesting that processes unique to the early period of motor neuron death enhance pLTF. This project increases our understanding of respiratory plasticity and its implications for breathing in motor neuron disease. Copyright © 2017 Elsevier B.V. All rights reserved.

  11. Protein and metabolite composition of xylem sap from field-grown soybeans (Glycine max).

    Science.gov (United States)

    Krishnan, Hari B; Natarajan, Savithiry S; Bennett, John O; Sicher, Richard C

    2011-05-01

    The xylem, in addition to transporting water, nutrients and metabolites, is also involved in long-distance signaling in response to pathogens, symbionts and environmental stresses. Xylem sap has been shown to contain a number of proteins including metabolic enzymes, stress-related proteins, signal transduction proteins and putative transcription factors. Previous studies on xylem sap have mostly utilized plants grown in controlled environmental chambers. However, plants in the field are subjected to high light and to environmental stress that is not normally found in growth chambers. In this study, we have examined the protein and metabolite composition of xylem sap from field-grown cultivated soybean plants. One-dimensional gel electrophoresis of xylem sap from determinate, indeterminate, nodulating and non-nodulating soybean cultivars revealed similar protein profiles consisting of about 8-10 prominent polypeptides. Two-dimensional gel electrophoresis of soybean xylem sap resulted in the visualization of about 60 distinct protein spots. A total of 38 protein spots were identified using MALDI-TOF MS and LC-MS/MS. The most abundant proteins present in the xylem sap were identified as 31 and 28 kDa vegetative storage proteins. In addition, several proteins that are conserved among different plant species were also identified. Diurnal changes in the metabolite profile of xylem sap collected during a 24-h cycle revealed that asparagine and aspartate were the two predominant amino acids irrespective of the time collected. Pinitol (D-3-O-methyl-chiro-inositol) was the most abundant carbohydrate present. The possible roles of xylem sap proteins and metabolites as nutrient reserves for sink tissue and as an indicator of biotic stress are also discussed.

  12. Building an electronic resource collection a practical guide

    CERN Document Server

    Lee, Stuart D

    2004-01-01

    This practical book guides information professionals step-by-step through building and managing an electronic resource collection. It outlines the range of electronic products currently available in abstracting and indexing, bibliographic, and other services and then describes how to effectively select, evaluate and purchase them.

  13. Analysis of Human Resources Management Strategy in China Electronic Commerce Enterprises

    Science.gov (United States)

    Shao, Fang

    The paper discussed electronic-commerce's influence on enterprise human resources management, proposed and proved the human resources management strategy which electronic commerce enterprise should adopt from recruitment strategy to training strategy, keeping talent strategy and other ways.

  14. The finite element structural analysis code SAP IV conversion from CDC to IBM

    International Nuclear Information System (INIS)

    Harrop, L.P.

    1977-02-01

    SAP IV is a general three dimensional, linear, static and dynamic finite element structural analysis program. The program which was obtained from the Earthquake Engineering Research Center, University of California, Berkeley, was written in FORTRAM for a CDC 6400. Its main use was anticipated to be the seismic analysis of reactor structures. SAP IV may also prove useful for fracture mechanics studies as well as the usual elastic stress analysis of structures. A brief description of SAP IV and a more detailed account of the FORTRAN conversion required to make SAP IV run successfully on the UKAEA Harwell IBM 370/168 are given. (author)

  15. Water relations link carbon and oxygen isotope discrimination to phloem sap sugar concentration in eucalyptus globulus

    International Nuclear Information System (INIS)

    Cernusak, L.A.; Farquhar, G.D.; Arthur, D.J; Pate, J.S.

    2002-01-01

    Full text: The carbon isotope ratio of phloem sap sugars has been previously observed to correlate strongly with the phloem sap sugar concentration in Eucalyptus globulus. We hypothesized that the correspondence between these two parameters results from co-linearity in their responses to variation in plant water potential. Carbon isotope discrimination is expected to decrease with decreasing plant water potential due to the influence of stomatal conductance on the ratio of intercellular to ambient CO 2 , concentrations (c 1 /c a ). Conversely, we expected the phloem sap sugar concentration to increase with decreasing plant water potential, thereby maintaining positive turgor pressure within the sieve tubes. The study comprised 40 individual Eucalyptus globulus trees growing in three plantations situated on opposing ends of a rainfall gradient in southwestern Australia. A strong correlation was observed between the carbon isotope ratio in phloem sap sugars and phloem sap sugar concentration. Carbon isotope discrimination correlated positively with shoot water potential, whereas phloem sap sugar concentration correlated negatively with shoot water potential. The relationship between carbon isotope discrimination measured in phloem sap sugars collected from the stem and c 1 /c a measured instantaneously on subtending leaves was close to that theoretically predicted. Accordingly, a strong, negative relationship was observed between instantaneous c 1 /c a and the phloem sap sugar concentration. Oxygen isotope discrimination in phloem sap sugars also correlated strongly with phloem sap sugar concentration. A theoretical model suggested that the observed variation in stomatal conductance was sufficient to account for the variation observed in oxygen isotope discrimination across the study. Results strongly support the contention that water relations form a mechanistic link between phloem sap sugar concentration and both instantaneous and integrated measures of the

  16. Fast susceptibility-weighted imaging with three-dimensional short-axis propeller (SAP)-echo-planar imaging.

    Science.gov (United States)

    Holdsworth, Samantha J; Yeom, Kristen W; Moseley, Michael E; Skare, S

    2015-05-01

    Susceptibility-weighted imaging (SWI) in neuroimaging can be challenging due to long scan times of three-dimensional (3D) gradient recalled echo (GRE), while faster techniques such as 3D interleaved echo-planar imaging (iEPI) are prone to motion artifacts. Here we outline and implement a 3D short-axis propeller echo-planar imaging (SAP-EPI) trajectory as a faster, motion-correctable approach for SWI. Experiments were conducted on a 3T MRI system. The 3D SAP-EPI, 3D iEPI, and 3D GRE SWI scans were acquired on two volunteers. Controlled motion experiments were conducted to test the motion-correction capability of 3D SAP-EPI. The 3D SAP-EPI SWI data were acquired on two pediatric patients as a potential alternative to 2D GRE used clinically. The 3D GRE images had a better target resolution (0.47 × 0.94 × 2 mm, scan time = 5 min), iEPI and SAP-EPI images (resolution = 0.94 × 0.94 × 2 mm) were acquired in a faster scan time (1:52 min) with twice the brain coverage. SAP-EPI showed motion-correction capability and some immunity to undersampling from rejected data. While 3D SAP-EPI suffers from some geometric distortion, its short scan time and motion-correction capability suggest that SAP-EPI may be a useful alternative to GRE and iEPI for use in SWI, particularly in uncooperative patients. © 2014 Wiley Periodicals, Inc.

  17. Using XML Technologies to Organize Electronic Reference Resources

    OpenAIRE

    Huser, Vojtech; Del Fiol, Guilherme; Rocha, Roberto A.

    2005-01-01

    Provision of access to reference electronic resources to clinicians is becoming increasingly important. We have created a framework for librarians to manage access to these resources at an enterprise level, rather than at the individual hospital libraries. We describe initial project requirements, implementation details, and some preliminary results.

  18. The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation.

    Science.gov (United States)

    Das, Rupali; Bassiri, Hamid; Guan, Peng; Wiener, Susan; Banerjee, Pinaki P; Zhong, Ming-Chao; Veillette, André; Orange, Jordan S; Nichols, Kim E

    2013-04-25

    The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) plays critical roles during invariant natural killer T (iNKT) cell ontogeny. As a result, SAP-deficient humans and mice lack iNKT cells. The strict developmental requirement for SAP has made it difficult to discern its possible involvement in mature iNKT cell functions. By using temporal Cre recombinase-mediated gene deletion to ablate SAP expression after completion of iNKT cell development, we demonstrate that SAP is essential for T-cell receptor (TCR)-induced iNKT cell cytotoxicity against T-cell and B-cell leukemia targets in vitro and iNKT-cell-mediated control of T-cell leukemia growth in vivo. These findings are not restricted to the murine system: silencing RNA-mediated suppression of SAP expression in human iNKT cells also significantly impairs TCR-induced cytolysis. Mechanistic studies reveal that iNKT cell killing requires the tyrosine kinase Fyn, a known SAP-binding protein. Furthermore, SAP expression is required within iNKT cells to facilitate their interaction with T-cell targets and induce reorientation of the microtubule-organizing center to the immunologic synapse (IS). Collectively, these studies highlight a novel and essential role for SAP during iNKT cell cytotoxicity and formation of a functional IS.

  19. Electronic Resources and Mission Creep: Reorganizing the Library for the Twenty-First Century

    Science.gov (United States)

    Stachokas, George

    2009-01-01

    The position of electronic resources librarian was created to serve as a specialist in the negotiation of license agreements for electronic resources, but mission creep has added more functions to the routine work of electronic resources such as cataloging, gathering information for collection development, and technical support. As electronic…

  20. DMPD: The SAP family of adaptors in immune regulation. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 15541655 The SAP family of adaptors in immune regulation. Latour S, Veillette A. Se...min Immunol. 2004 Dec;16(6):409-19. (.png) (.svg) (.html) (.csml) Show The SAP family of adaptors in immune ...regulation. PubmedID 15541655 Title The SAP family of adaptors in immune regulation. Authors Latour S, Veill

  1. SAP expression in invariant NKT cells is required for cognate help to support B-cell responses.

    Science.gov (United States)

    Detre, Cynthia; Keszei, Marton; Garrido-Mesa, Natividad; Kis-Toth, Katalin; Castro, Wilson; Agyemang, Amma F; Veerapen, Natacha; Besra, Gurdyal S; Carroll, Michael C; Tsokos, George C; Wang, Ninghai; Leadbetter, Elizabeth A; Terhorst, Cox

    2012-07-05

    One of the manifestations of X-linked lymphoproliferative disease (XLP) is progressive agammaglobulinemia, caused by the absence of a functional signaling lymphocyte activation molecule (SLAM)-associated protein (SAP) in T, invariant natural killer T (NKT) cells and NK cells. Here we report that α-galactosylceramide (αGalCer) activated NKT cells positively regulate antibody responses to haptenated protein antigens at multiple checkpoints, including germinal center formation and affinity maturation. Whereas NKT cell-dependent B cell responses were absent in SAP(-/-).B6 mice that completely lack NKT cells, the small number of SAP-deficient NKT cells in SAP(-/-).BALB/c mice adjuvated antibody production, but not the germinal center reaction. To test the hypothesis that SAP-deficient NKT cells can facilitate humoral immunity, SAP was deleted after development in SAP(fl/fl).tgCreERT2.B6 mice. We find that NKT cell intrinsic expression of SAP is dispensable for noncognate helper functions, but is critical for providing cognate help to antigen-specific B cells. These results demonstrate that SLAM-family receptor-regulated cell-cell interactions are not limited to T-B cell conjugates. We conclude that in the absence of SAP, several routes of NKT cell-mediated antibody production are still accessible. The latter suggests that residual NKT cells in XLP patients might contribute to variations in dysgammaglobulinemia.

  2. Sulfonic-based precursors (SAPs for silica mesostructures: Advances in synthesis and applications

    Directory of Open Access Journals (Sweden)

    Sadegh Rostamnia*

    2016-01-01

    Full Text Available Sulfonic acid-based precursors (SAP play an important role in tailoring mesoporous silica’s and convert them to a solid acid catalyst with a Bronsted-type nature. These kinds of solid acids contribute to sustainable and green chemistry by their heterogeneous, recyclable, and high efficiency features. Therefore, knowing the properties and reactivity of SAPs can guide us to manufacture a sulfonated mesostructures compatible with reaction type and conditions. In the present review, some of the important SAPs, their reactivity and mechanism of functionalization are discussed.

  3. Set anode potentials affect the electron fluxes and microbial community structure in propionate-fed microbial electrolysis cells

    KAUST Repository

    Rao, Hari Ananda

    2016-12-09

    Anode potential has been shown to be a critical factor in the rate of acetate removal in microbial electrolysis cells (MECs), but studies with fermentable substrates and set potentials are lacking. Here, we examined the impact of three different set anode potentials (SAPs; −0.25, 0, and 0.25 V vs. standard hydrogen electrode) on the electrochemical performance, electron flux to various sinks, and anodic microbial community structure in two-chambered MECs fed with propionate. Electrical current (49–71%) and CH4 (22.9–41%) were the largest electron sinks regardless of the potentials tested. Among the three SAPs tested, 0 V showed the highest electron flux to electrical current (71 ± 5%) and the lowest flux to CH4 (22.9 ± 1.2%). In contrast, the SAP of −0.25 V had the lowest electron flux to current (49 ± 6%) and the highest flux to CH4 (41.1 ± 2%). The most dominant genera detected on the anode of all three SAPs based on 16S rRNA gene sequencing were Geobacter, Smithella and Syntrophobacter, but their relative abundance varied among the tested SAPs. Microbial community analysis implies that complete degradation of propionate in all the tested SAPs was facilitated by syntrophic interactions between fermenters and Geobacter at the anode and ferementers and hydrogenotrophic methanogens in suspension.

  4. Electronic Resources Management System: Recommendation Report 2017

    KAUST Repository

    Ramli, Rindra M.

    2017-01-01

    This recommendation report provides an overview of the selection process for the new Electronic Resources Management System. The library has decided to move away from Innovative Interfaces Millennium ERM module. The library reviewed 3 system

  5. Adulteration and Contamination of Commercial Sap of Hymenaea Species

    Directory of Open Access Journals (Sweden)

    Katyuce de Souza Farias

    2017-01-01

    Full Text Available The Hymenaea stigonocarpa and Hymenaea martiana species, commonly known as “jatobá,” produce a sap which is extracted by perforation of the trunk and is commonly used in folk medicine as a tonic. For this study, the authenticity of commercial samples of jatobá was verified by the identification of the main compounds and multivariate analysis and contamination by microbial presence analysis. The acute toxicity of the authentic jatobá sap was also evaluated. The metabolites composition and multivariate analysis revealed that none of the commercial samples were authentic. In the microbiological contamination analysis, five of the six commercial samples showed positive cultures within the range of 1,700–100,000 CFU/mL and the authentic sap produced no signs of toxicity, and from a histological point of view, there was the maintenance of tissue integrity. In brief, the commercial samples were deemed inappropriate for consumption and represent a danger to the population.

  6. Sap flow characteristics of neotropical mangroves in flooded and drained soils

    Science.gov (United States)

    Krauss, Ken W.; Young, P. Joy; Chambers, Jim L.; Doyle, Thomas W.; Twilley, Robert R.

    2007-01-01

    Effects of flooding on water transport in mangroves have previously been investigated in a few studies, most of which were conducted on seedlings in controlled settings. In this study, we used heat-dissipation sap probes to determine if sap flow (Js) attenuates with radial depth into the xylem of mature trees of three south Florida mangrove species growing in Rookery Bay. This was accomplished by inserting sap probes at multiple depths and monitoring diurnal flow. For most species and diameter size class combinations tested, Js decreased dramatically beyond a radial depth of 2 or 4 cm, with little sap flow beyond a depth of 6 cm. Mean Js was reduced on average by 20% in Avicennia germinans (L.) Stearn, Laguncularia racemosa (L.) Gaertn. f. and Rhizophora mangle L. trees when soils were flooded. Species differences were highly significant, with L. racemosahaving the greatest midday Js of about 26g H2O H2O m−2s−1 at a radial depth of 2 cm compared with a mean for the other two species of about 15 g H2O m−2s−1. Sap flow at a depth of 2 cm in mangroves was commensurate with rates reported for other forested wetland tree species. We conclude that: (1) early spring flooding of basin mangrove forests causes reductions in sap flow in mature mangrove trees; (2) the sharp attenuations in Js along the radial profile have implications for understanding whole-tree water use strategies by mangrove forests; and (3) regardless of flood state, individual mangrove tree water use follows leaf-level mechanisms in being conservative.

  7. Mechanical properties of Concrete with SAP. Part I: Development of compressive strength

    DEFF Research Database (Denmark)

    Hasholt, Marianne Tange; Jespersen, Morten H. Seneka; Jensen, Ole Mejlhede

    2010-01-01

    The development of mechanical properties has been studied in a test program comprising 15 different concrete mixes with 3 different w/c ratios and different additions of superabsorbent polymers (SAP). The degree of hydration is followed for 15 corresponding paste mixes. This paper concerns...... compressive strength. It shows that results agree well with a model based on the following: 1. Concrete compressive strength is proportional to compressive strength of the paste phase 2. Paste strength depends on gel space ratio, as suggested by Powers 3. The influence of air voids created by SAP...... on compressive strength can be accounted for in the same way as when taking the air content into account in Bolomeys formula. The implication of the model is that at low w/c ratios (w/c SAP additions, SAP increases the compressive strength at later ages (from 3 days after casting and onwards...

  8. The Internet School of Medicine: use of electronic resources by medical trainees and the reliability of those resources.

    Science.gov (United States)

    Egle, Jonathan P; Smeenge, David M; Kassem, Kamal M; Mittal, Vijay K

    2015-01-01

    Electronic sources of medical information are plentiful, and numerous studies have demonstrated the use of the Internet by patients and the variable reliability of these sources. Studies have investigated neither the use of web-based resources by residents, nor the reliability of the information available on these websites. A web-based survey was distributed to surgical residents in Michigan and third- and fourth-year medical students at an American allopathic and osteopathic medical school and a Caribbean allopathic school regarding their preferred sources of medical information in various situations. A set of 254 queries simulating those faced by medical trainees on rounds, on a written examination, or during patient care was developed. The top 5 electronic resources cited by the trainees were evaluated for their ability to answer these questions accurately, using standard textbooks as the point of reference. The respondents reported a wide variety of overall preferred resources. Most of the 73 responding medical trainees favored textbooks or board review books for prolonged studying, but electronic resources are frequently used for quick studying, clinical decision-making questions, and medication queries. The most commonly used electronic resources were UpToDate, Google, Medscape, Wikipedia, and Epocrates. UpToDate and Epocrates had the highest percentage of correct answers (47%) and Wikipedia had the lowest (26%). Epocrates also had the highest percentage of wrong answers (30%), whereas Google had the lowest percentage (18%). All resources had a significant number of questions that they were unable to answer. Though hardcopy books have not been completely replaced by electronic resources, more than half of medical students and nearly half of residents prefer web-based sources of information. For quick questions and studying, both groups prefer Internet sources. However, the most commonly used electronic resources fail to answer clinical queries more than half

  9. Enhanced production and purification of recombinant surface array protein (Sap) for use in detection of Bacillus anthracis.

    Science.gov (United States)

    Puranik, Nidhi; Tripathi, N K; Pal, V; Goel, Ajay Kumar

    2018-05-01

    Surface array protein (Sap) can be an important biomarker for specific detection of Bacillus anthracis , which is released by the bacterium during its growth in culture broth. In the present work, we have cloned and expressed Sap in Escherichia coli . The culture conditions and cultivation media were optimized and used in batch fermentation process for scale up of Sap in soluble form. The recombinant Sap was purified employing affinity chromatography followed by diafiltration. The final yield of purified protein was 20 and 46 mg/l of culture during shake flasks and batch fermentation, respectively. The protein purity and its reactivity were confirmed employing SDS-PAGE and Western blot, respectively. The antibodies raised against purified Sap were evaluated by Western blotting for detection of Sap released by B. anthracis . Our results showed that the Sap could be a novel marker for detection and confirmation of B. anthracis .

  10. Critical role of SAP in progression and reactivation but not maintenance of T cell-dependent humoral immunity.

    Science.gov (United States)

    Zhong, Ming-Chao; Veillette, André

    2013-03-01

    Signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is a small adaptor molecule mutated in X-linked lymphoproliferative disease, a human immunodeficiency. SAP plays a critical role in the initiation of T cell-dependent B cell responses leading to germinal center reaction, the production of high-affinity antibodies, and B cell memory. However, whether SAP has a role in these responses beyond their initiation is not known. It is important to address this matter not only for mechanistic reasons but also because blockade of the SAP pathway is being contemplated as a means to treat autoimmune diseases in humans. Using an inducibly SAP deficient mouse, we found that SAP was required not only for the initiation but also for the progression of primary T cell-driven B cell responses to haptens. It was also necessary for the reactivation of T cell-dependent B cell immunity during secondary immune responses. These activities consistently correlated with the requirement of SAP for full expression of the lineage commitment factor Bcl-6 in follicular T helper (T(FH)) cells. However, once memory B cells and long-lived antibody-secreting cells were established, SAP became dispensable for maintaining T cell-dependent B cell responses. Thus, SAP is pivotal for nearly all phases, but not for maintenance, of T cell-driven B cell humoral immunity. These findings may have implications for the treatment of immune disorders by targeting the SAP pathway.

  11. Tree Hydraulics: How Sap Rises

    Science.gov (United States)

    Denny, Mark

    2012-01-01

    Trees transport water from roots to crown--a height that can exceed 100 m. The physics of tree hydraulics can be conveyed with simple fluid dynamics based upon the Hagen-Poiseuille equation and Murray's law. Here the conduit structure is modelled as conical pipes and as branching pipes. The force required to lift sap is generated mostly by…

  12. 49 CFR 40.289 - Are employers required to provide SAP and treatment services to employees?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Are employers required to provide SAP and... Professionals and the Return-to-Duty Process § 40.289 Are employers required to provide SAP and treatment services to employees? (a) As an employer, you are not required to provide a SAP evaluation or any...

  13. 49 CFR 40.297 - Does anyone have the authority to change a SAP's initial evaluation?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Does anyone have the authority to change a SAP's... the Return-to-Duty Process § 40.297 Does anyone have the authority to change a SAP's initial... managed-care provider, any service agent) may change in any way the SAP's evaluation or recommendations...

  14. Dissolved atmospheric gas in xylem sap measured with membrane inlet mass spectrometry.

    Science.gov (United States)

    Schenk, H Jochen; Espino, Susana; Visser, Ate; Esser, Bradley K

    2016-04-01

    A new method is described for measuring dissolved gas concentrations in small volumes of xylem sap using membrane inlet mass spectrometry. The technique can be used to determine concentrations of atmospheric gases, such as argon, as reported here, or for any dissolved gases and their isotopes for a variety of applications, such as rapid detection of trace gases from groundwater only hours after they were taken up by trees and rooting depth estimation. Atmospheric gas content in xylem sap directly affects the conditions and mechanisms that allow for gas removal from xylem embolisms, because gas can dissolve into saturated or supersaturated sap only under gas pressure that is above atmospheric pressure. The method was tested for red trumpet vine, Distictis buccinatoria (Bignoniaceae), by measuring atmospheric gas concentrations in sap collected at times of minimum and maximum daily temperature and during temperature increase and decline. Mean argon concentration in xylem sap did not differ significantly from saturation levels for the temperature and pressure conditions at any time of collection, but more than 40% of all samples were supersaturated, especially during the warm parts of day. There was no significant diurnal pattern, due to high variability between samples. © 2015 John Wiley & Sons Ltd.

  15. Assessing ERP SAP implementation in the small and medium enterprises (SMEs) in Indonesia

    Science.gov (United States)

    Yohannes; Gunawan, W.; Ikhsan, R. B.; Aries

    2018-03-01

    The consistent growth of Indonesian SMEs has received attention of global IT vendors. One of major ERP player in Indonesian market such as SAP, has introduced ERP solutions for SMEs through SAP Business One. Due to its fast growth, unfortunately, there are still very few articles can be found to understand the ERP implementation in Indonesian SMEs. The article addressed the common factors that affect the successful of the ERP implementation at SMEs. They are: identifying vendor quality, opening balance data migration, and A-SAP methodology. The article applied case study method to examine the fast growth companies owned by same owners, such as: GRK, MMM, and KM25; with the objectives to identify the practical pattern of ERP implementation in SMEs that will be useful for SAP project manager and consultants.

  16. Stormtime Simulations of Sub-Auroral Polarization Streams (SAPS)

    Science.gov (United States)

    Huba, J.; Sazykin, S. Y.; Coster, A. J.

    2017-12-01

    We present simulation results from the self-consistently coupled SAMI3/RCM code on the impact of geomagnetic storms on the ionosphere/plasmasphere system with an emphasis on the development of sub-auroral plasma streams (SAPS). We consider the following storm events: March 31, 2001, March 17, 2013, March 17, 2015, September 3, 2012, and June 23, 2015. We compare and contrast the development of SAPS for these storms. The main results are the development of sub-auroral (< 60 degrees) low-density, high-speed flows (1 - 2 km/s). Additionally, we discuss the impact on plasmaspheric dynamics. We compare our model results to data (e.g., Millstone Hill radar, GPS TEC).

  17. SCF(SAP) controls organ size by targeting PPD proteins for degradation in Arabidopsis thaliana.

    Science.gov (United States)

    Wang, Zhibiao; Li, Na; Jiang, Shan; Gonzalez, Nathalie; Huang, Xiahe; Wang, Yingchun; Inzé, Dirk; Li, Yunhai

    2016-04-06

    Control of organ size by cell proliferation and growth is a fundamental process, but the mechanisms that determine the final size of organs are largely elusive in plants. We have previously revealed that the ubiquitin receptor DA1 regulates organ size by repressing cell proliferation in Arabidopsis. Here we report that a mutant allele of STERILE APETALA (SAP) suppresses the da1-1 mutant phenotype. We show that SAP is an F-box protein that forms part of a SKP1/Cullin/F-box E3 ubiquitin ligase complex and controls organ size by promoting the proliferation of meristemoid cells. Genetic analyses suggest that SAP may act in the same pathway with PEAPOD1 and PEAPOD2, which are negative regulators of meristemoid proliferation, to control organ size, but does so independently of DA1. Further results reveal that SAP physically associates with PEAPOD1 and PEAPOD2, and targets them for degradation. These findings define a molecular mechanism by which SAP and PEAPOD control organ size.

  18. An interactive tool for processing sap flux data from thermal dissipation probes

    Science.gov (United States)

    Andrew C. Oishi; Chelcy F. Miniat

    2016-01-01

    Sap flux sensors are an important tool for estimating tree-level transpiration in forested and urban ecosystems around the world. Thermal dissipation (TD) or Granier-type sap flux probes are among the most commonly used due to their reliability, simplicity, and low cost.

  19. [Application of three heat pulse technique-based methods to determine the stem sap flow].

    Science.gov (United States)

    Wang, Sheng; Fan, Jun

    2015-08-01

    It is of critical importance to acquire tree transpiration characters through sap flow methodology to understand tree water physiology, forest ecology and ecosystem water exchange. Tri-probe heat pulse sensors, which are widely utilized in soil thermal parameters and soil evaporation measurement, were applied to implement Salix matsudana sap flow density (Vs) measurements via heat-ratio method (HRM), T-Max method (T-Max) and single-probe heat pulse probe (SHPP) method, and comparative analysis was conducted with additional Grainer's thermal diffusion probes (TDP) measured results. The results showed that, it took about five weeks to reach a stable measurement stage after TPHP installation, Vs measured with three methods in the early stage after installation was 135%-220% higher than Vs in the stable measurement stage, and Vs estimated via HRM, T-Max and SHPP methods were significantly linearly correlated with Vs estimated via TDP method, with R2 of 0.93, 0.73 and 0.91, respectively, and R2 for Vs measured by SHPP and HRM reached 0.94. HRM had relatively higher precision in measuring low rates and reverse sap flow. SHPP method seemed to be very promising to measure sap flow for configuration simplicity and high measuring accuracy, whereas it couldn' t distinguish directions of flow. T-Max method had relatively higher error in sap flow measurement, and it couldn' t measure sap flow below 5 cm3 · cm(-2) · h(-1), thus this method could not be used alone, however it could measure thermal diffusivity for calculating sap flow when other methods were imposed. It was recommended to choose a proper method or a combination of several methods to measure stem sap flow, based on specific research purpose.

  20. ANALYTICAL REVIEW OF ELECTRONIC RESOURCES FOR THE STUDY OF LATIN

    Directory of Open Access Journals (Sweden)

    Olena Yu. Balalaieva

    2014-04-01

    Full Text Available The article investigates the current state of development of e-learning content in the Latin language. It is noted that the introduction of ICT in the educational space has expanded the possibility of studying Latin, opened access to digital libraries resources, made it possible to use scientific and educational potential and teaching Latin best practices of world's leading universities. A review of foreign and Ukrainian information resources and electronic editions for the study of Latin is given. Much attention was paid to the didactic potential of local and online multimedia courses of Latin, electronic textbooks, workbooks of interactive tests and exercises, various dictionaries and software translators, databases and digital libraries. Based on analysis of the world market of educational services and products the main trends in the development of information resources and electronic books are examined. It was found that multimedia courses with interactive exercises or workbooks with interactive tests, online dictionaries and translators are the most widely represented and demanded. The noticeable lagging of Ukrainian education and computer linguistics in quantitative and qualitative measures in this industry is established. The obvious drawback of existing Ukrainian resources and electronic editions for the study of Latin is their noninteractive nature. The prospects of e-learning content in Latin in Ukraine are outlined.

  1. Stabilization/Solidification of Radioactive LiCl-KCl Waste Salt by Using SiO{sub 2}-Al{sub 2}O{sub 3}-P{sub 2}O{sub 5}(SAP) Inorganic Composite: Part 2. The Effect of SAP Composition on Stabilization/Solidification

    Energy Technology Data Exchange (ETDEWEB)

    Ahn, Soo Na; Park, Hwan Seo; Cho, In Hak; Kim, In Tae; Cho, Yong Zun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-03-15

    Metal chloride waste is generated as a main waste streams in a series of electrolytic processes of a pyrochemical process. Different from carbonate or nitrate salt, metal chloride is not decomposed into oxide and chlorine but it is just vaporized. Also, it has low compatibility with conventional silicate glasses. Our research group adapted the dechlorination approach for the immobilization of waste salt. In this study, the composition of SAP (SiO{sub 2}-Al{sub 2}O{sub 3}-P{sub 2}O{sub 5}) was adjusted to enhance the reactivity and to simplify the solidification process as a subsequent research. The addition of Fe{sub 2}O{sub 3} into the basic SAP decreased the SAP/Salt ratio in weight from 3 for SAP 1071 to 2.25 for M-SAP(Fe=0.1). The experimental results indicated that the addition of Fe{sub 2}O{sub 3} increased the reactivity of M-SAP with LiCl-KCl but the reactivity gradually decreased above Fe=0.1. Also, introducing B{sub 2}O{sub 3} into M-SAP requires no glass binder for the consolidation of reaction products. U-SAP (SiO{sub 2}-Al{sub 2}O{sub 3}-P{sub 2}O{sub 5}) could effectively dechlorinate the LiCl-KCl waste and its reaction product could be consolidated as a monolithic form without a glass binder. The leaching test result indicated that U-SAP 1071 was more durable than other SAPs wasteform. By using U-SAP, 1 g of waste salt could generated 3 - 4 g of wasteform for final disposal. The final volume would be about 3 - 4 times lower than the glass-bonded sodalite. From these results, it could be concluded that the dechlorination approach using U-SAP would be one of prospective methods to manage the volatile waste salt.

  2. Elektronik Bilgi Kaynaklarının Seçimi / Selection of Electronic Information Resources

    Directory of Open Access Journals (Sweden)

    Pınar Al

    2003-04-01

    Full Text Available For many years, library users have used only from the printed media in order to get the information that they have needed. Today with the widespread use of the Web and the addition of electronic information resources to library collections, the use of information in the electronic environment as well as in printed media is started to be used. In time, such types of information resources as, electronic journals, electronic books, electronic encyclopedias, electronic dictionaries and electronic theses have been added to library collections. In this study, selection criteria that can be used for electronic information resources are discussed and suggestions are provided for libraries that try to select electronic information resources for their collections.

  3. Access to electronic resources by visually impaired people

    Directory of Open Access Journals (Sweden)

    Jenny Craven

    2003-01-01

    Full Text Available Research into access to electronic resources by visually impaired people undertaken by the Centre for Research in Library and Information Management has not only explored the accessibility of websites and levels of awareness in providing websites that adhere to design for all principles, but has sought to enhance understanding of information seeking behaviour of blind and visually impaired people when using digital resources.

  4. The sap of Acer okamotoanum decreases serum alcohol levels after acute ethanol ingestion in rats.

    Science.gov (United States)

    Yoo, Yeong-Min; Jung, Eui-Man; Kang, Ha-Young; Choi, In-Gyu; Choi, Kyung-Chul; Jeung, Eui-Bae

    2011-10-01

    In the present study, we examined whether Acer okamotoanum (A. okamotoanum) sap decreased the serum alcohol and acetaldehyde levels after acute ethanol treatment in a rat model. Male rats were orally administered 25, 50 or 100% A. okamotoanum sap 30 min prior to oral challenge with 3 ml of ethanol (15 ml/kg of a 20% ethanol solution in water), and the blood concentrations of alcohol and acetaldehyde were analyzed up to 7 h after the treatment. Pre-treatment with the sap significantly decreased the blood ethanol and acetaldehyde concentrations after 5 h when compared with ethanol treatment alone (a negative control). The expression levels of liver alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) mRNA were increased significantly in animals pre-treated with A. okamotoanum sap when compared with negative and positive controls. The data suggest that sap pre-treatment enhanced the alcohol metabolism rate in the rat liver. To investigate the involvement of mitochondrial regulation in the ethanol-induced hepatocyte apoptosis, we carried out an immunohistochemical analysis of Bax and Bcl-2. Pre-treatment with sap significantly decreased Bax expression and increased Bcl-2 expression 7 h after ethanol administration when compared with the negative control. The data suggest that A. okamotoanum sap pre-treatment may reduce the alcohol-induced oxidative stress in the rat liver.

  5. Leaf temperature and stomatal influences on sap velocity diurnal hysteresis in the Amazon rainforest

    Science.gov (United States)

    Jardine, K.; Gimenez, B.; Negron Juarez, R. I.; Koven, C.; Powell, T.; Higuchi, N.; Chambers, J.; Varadharajan, C.

    2016-12-01

    In order to improve our ability to predict terrestrial evapotranspiration fluxes, an understanding of the interactions between plant physiology and environmental conditions is necessary, but remains poorly characterized, especially in tropical ecosystems. In this study we show a tight positive correlation between sap velocity (at 1 m of height) and leaf surface temperature (LST, 20-30 m of height) in canopy dominant trees in two primary rainforest sites in the Amazon basin (Santarém and Manaus, Brazil). As leaf temperatures varied throughout the day, sap velocity responded with little delay (<15 min). Positive sap velocity was often observed at night, but also closely followed night time LSTs. When plotted versus LST, sap velocity showed an exponential increase before reaching a reflection point and a plateau and is characterized as a sigmoidal curve, in all observed trees. Moreover, a clear diurnal hysteresis in sap velocity was evident with morning periods showing higher temperature sensitivities than afternoon and night periods. Diurnal leaf observations showed a morning peak in stomatal conductance ( 10:00-10:30), but a mid-day to afternoon peak in transpiration and leaf temperature (12:00-14:00). Our observations suggest the sap velocity-LST hysteresis pattern arises due to the temporal offset between stomatal conductance and vapor pressure deficits (VPD) and demonstrates the dominating effect of VPD over stomatal conductance in maintaining high transpiration/sap flow rates under elevated temperatures. Our results have important implications for modeling tropical forest transpiration and suggests the possibility of predicting evapotranspiration fluxes at the ecosystem to regional scales based on remote sensed vegetation temperature.

  6. [Expression of PARP/NF-κB and intervention effect of 5-AIQ/PDTC in SAP rats with adrenal damage].

    Science.gov (United States)

    Yang, Bo; Guo, Wen-Yi; Yu, Jia; Zhao, Kai-liang; Shi, Qiao; Zuo, Teng; Wang, Wei-xing

    2013-10-15

    To explore the expression of poly (ADP-ribose) polymerase/nuclear factor-κB (PARP/NF-κB) and intervention effect of 5-aminoisoquinolinone/pyrrolidine dithiocarbamate (5-AIQ/PDTC) in severe acute pancreatitis (SAP) rats with adrenal damage. The primarily cultured adrenocortical cells were quantitatively divided into control group (SO), pancreatitis group (SAP), PDTC drug control group (SO+PDTC), PDTC intervention group (SAP+PDTC), 5-AIQ drug control group (SO+ 5-AIQ) and 5-AIQ intervention group (SAP+5-AIQ). The SAP and 2 intervention groups were stimulated with the sera of SAP rats. Then corresponding drugs were added and culture continued for 12 hours. The corticosterone levels and PARP/NF-κB expression were observed for each group. Adrenal cells in vitro cultured were round or oval, had secretory granules and could be stained by 3β-hydroxysteroid dehydrogenase antibody. The adherence rate was 60% after 48-hour culturing. The corticosterone level of SAP group was significantly lower than that of SO group [ (216.4 ± 15.7) vs (294.8 ± 16.3) µg/L, P SAP group (P SAP and PDTC intervention groups were higher than SO group while 5-AIQ intervention group was significantly lower than SAP and PDTC intervention groups, but higher than SO and drug control groups. The expression of NF-κB in SAP group was higher than that in SO group. Two intervention groups were lower than SAP group, but higher than SO and drug control groups. The pathway of PARP/NF-κB participates in adrenal damage of SAP rats. To a certain extent, the uses of 5-AIQ and PDTC may alleviate adrenal damage.

  7. Raw Sap Consumption Habits and Its Association with Knowledge of Nipah Virus in Two Endemic Districts in Bangladesh.

    Science.gov (United States)

    Nahar, Nazmun; Paul, Repon C; Sultana, Rebeca; Gurley, Emily S; Garcia, Fernando; Abedin, Jaynal; Sumon, Shariful Amin; Banik, Kajal Chandra; Asaduzzaman, Mohammad; Rimi, Nadia Ali; Rahman, Mahmudur; Luby, Stephen P

    2015-01-01

    Human Nipah virus (NiV) infection in Bangladesh is a fatal disease that can be transmitted from bats to humans who drink contaminated raw date palm sap collected overnight during the cold season. Our study aimed to understand date palm sap consumption habits of rural residents and factors associated with consumption. In November-December 2012 the field team interviewed adult respondents from randomly selected villages from Rajbari and Kushtia Districts in Bangladesh. We calculated the proportion of people who consumed raw sap and had heard about a disease from raw sap consumption. We assessed the factors associated with raw sap consumption by calculating prevalence ratios (PR) adjusted for village level clustering effects. Among the 1,777 respondents interviewed, half (50%) reported drinking raw sap during the previous sap collection season and 37% consumed raw sap at least once per month. Few respondents (5%) heard about NiV. Thirty-seven percent of respondents reported hearing about a disease transmitted through raw sap consumption, inclusive of a 10% who related it with milder illness like diarrhea, vomiting or indigestion rather than NiV. Respondents who harvested date palm trees in their household were more likely to drink sap than those who did not own date palm trees (79% vs. 65% PR 1.2, 95% CI 1.1-1.3, psap was available, respondents who heard about a disease from raw sap consumption were just as likely to drink it as those who did not hear about a disease (69% vs. 67%, PR 1.0, 95% CI 0.9-1.1, p = 0.512). Respondents' knowledge of NiV was low. They might not have properly understood the risk of NiV, and were likely to drink sap when it was available. Implementing strategies to increase awareness about the risks of NiV and protect sap from bats might reduce the risk of NiV transmission.

  8. Library training to promote electronic resource usage

    DEFF Research Database (Denmark)

    Frandsen, Tove Faber; Tibyampansha, Dativa; Ibrahim, Glory

    2017-01-01

    Purpose: Increasing the usage of electronic resources is an issue of concern for many libraries all over the world. Several studies stress the importance of information literacy and instruction in order to increase the usage. Design/methodology/approach: The present article presents the results...

  9. Why and How to Measure the Use of Electronic Resources

    Directory of Open Access Journals (Sweden)

    Jean Bernon

    2008-11-01

    Full Text Available A complete overview of library activity implies a complete and reliable measurement of the use of both electronic resources and printed materials. This measurement is based on three sets of definitions: document types, use types and user types. There is a common model of definitions for printed materials, but a lot of questions and technical issues remain for electronic resources. In 2006 a French national working group studied these questions. It relied on the COUNTER standard, but found it insufficient and pointed out the need for local tools such as web markers and deep analysis of proxy logs. Within the French national consortium COUPERIN, a new working group is testing ERMS, SUSHI standards, Shibboleth authentication, along with COUNTER standards, to improve the counting of the electronic resources use. At this stage this counting is insufficient and its improvement will be a European challenge for the future.

  10. Sap flow is Underestimated by Thermal Dissipation Sensors due to Alterations of Wood Anatomy

    Science.gov (United States)

    Marañón-Jiménez, S.; Wiedemann, A.; van den Bulcke, J.; Cuntz, M.; Rebmann, C.; Steppe, K.

    2014-12-01

    The thermal dissipation technique (TD) is one of the most commonly adopted methods for sap flow measurements. However, underestimations of up to 60% of the tree transpiration have been reported with this technique, although the causes are not certainly known. The insertion of TD sensors within the stems causes damage of the wood tissue and subsequent healing reactions, changing wood anatomy and likely the sap flow path. However, the anatomical changes in response to the insertion of sap flow sensors and the effects on the measured flow have not been assessed yet. In this study, we investigate the alteration of vessel anatomy on wounds formed around TD sensors. Our main objectives were to elucidate the anatomical causes of sap flow underestimation for ring-porous and diffuse-porous species, and relate these changes to sap flow underestimations. Successive sets of TD probes were installed in early, mid and end of the growing season in Fagus sylvatica (diffuse-porous) and Quercus petraea (ring-porous) trees. They were logged after the growing season and additional sets of sensors were installed in the logged stems with presumably no healing reaction. The wood tissue surrounding each sensor was then excised and analysed by X-ray computed microtomography (X-ray micro CT). This technique allowed the quantification of vessel anatomical characteristics and the reconstruction of the 3-D internal microstructure of the xylem vessels so that extension and shape of the altered area could be determined. Gels and tyloses clogged the conductive vessels around the sensors in both beech and oak. The extension of the affected area was larger for beech although these anatomical changes led to similar sap flow underestimations in both species. The higher vessel size in oak may explain this result and, therefore, larger sap flow underestimation per area of affected conductive tissue. The wound healing reaction likely occurred within the first weeks after sensor installation, which

  11. Grape Cultivar and Sap Culture Conditions Affect the Development of Xylella fastidiosa Phenotypes Associated with Pierce's Disease.

    Science.gov (United States)

    Hao, Lingyun; Zaini, Paulo A; Hoch, Harvey C; Burr, Thomas J; Mowery, Patricia

    2016-01-01

    Xylella fastidiosa is a xylem-limited bacterium in plant hosts and causes Pierce's disease (PD) of grapevines, which differ in susceptibility according to the Vitis species (spp.). In this work we compared X. fastidiosa biofilm formation and population dynamics when cultured in xylem saps from PD-susceptible and -resistant Vitis spp. under different conditions. Behaviors in a closed-culture system were compared to those in different sap-renewal cultures that would more closely mimic the physicochemical environment encountered in planta. Significant differences in biofilm formation and growth in saps from PD-susceptible and -resistant spp. were only observed using sap renewal culture. Compared to saps from susceptible V. vinifera, those from PD-resistant V. aestivalis supported lower titers of X. fastidiosa and less biofilm and V. champinii suppressed both growth and biofilm formation, behaviors which are correlated with disease susceptibility. Furthermore, in microfluidic chambers X. fastidiosa formed thick mature biofilm with three-dimensional (3-D) structures, such as pillars and mounds, in saps from all susceptible spp. In contrast, only small aggregates of various shapes were formed in saps from four out of five of the resistant spp.; sap from the resistant spp. V. mustangensis was an exception in that it also supported thick lawns of biofilm but not the above described 3-D structures typically seen in a mature biofilm from the susceptible saps. Our findings provide not only critical technical information for future bioassays, but also suggest further understanding of PD susceptibility.

  12. Grape Cultivar and Sap Culture Conditions Affect the Development of Xylella fastidiosa Phenotypes Associated with Pierce's Disease

    Science.gov (United States)

    Hoch, Harvey C.; Burr, Thomas J.; Mowery, Patricia

    2016-01-01

    Xylella fastidiosa is a xylem-limited bacterium in plant hosts and causes Pierce’s disease (PD) of grapevines, which differ in susceptibility according to the Vitis species (spp.). In this work we compared X. fastidiosa biofilm formation and population dynamics when cultured in xylem saps from PD-susceptible and -resistant Vitis spp. under different conditions. Behaviors in a closed-culture system were compared to those in different sap-renewal cultures that would more closely mimic the physicochemical environment encountered in planta. Significant differences in biofilm formation and growth in saps from PD-susceptible and -resistant spp. were only observed using sap renewal culture. Compared to saps from susceptible V. vinifera, those from PD-resistant V. aestivalis supported lower titers of X. fastidiosa and less biofilm and V. champinii suppressed both growth and biofilm formation, behaviors which are correlated with disease susceptibility. Furthermore, in microfluidic chambers X. fastidiosa formed thick mature biofilm with three-dimensional (3-D) structures, such as pillars and mounds, in saps from all susceptible spp. In contrast, only small aggregates of various shapes were formed in saps from four out of five of the resistant spp.; sap from the resistant spp. V. mustangensis was an exception in that it also supported thick lawns of biofilm but not the above described 3-D structures typically seen in a mature biofilm from the susceptible saps. Our findings provide not only critical technical information for future bioassays, but also suggest further understanding of PD susceptibility. PMID:27508296

  13. Grape Cultivar and Sap Culture Conditions Affect the Development of Xylella fastidiosa Phenotypes Associated with Pierce's Disease.

    Directory of Open Access Journals (Sweden)

    Lingyun Hao

    Full Text Available Xylella fastidiosa is a xylem-limited bacterium in plant hosts and causes Pierce's disease (PD of grapevines, which differ in susceptibility according to the Vitis species (spp.. In this work we compared X. fastidiosa biofilm formation and population dynamics when cultured in xylem saps from PD-susceptible and -resistant Vitis spp. under different conditions. Behaviors in a closed-culture system were compared to those in different sap-renewal cultures that would more closely mimic the physicochemical environment encountered in planta. Significant differences in biofilm formation and growth in saps from PD-susceptible and -resistant spp. were only observed using sap renewal culture. Compared to saps from susceptible V. vinifera, those from PD-resistant V. aestivalis supported lower titers of X. fastidiosa and less biofilm and V. champinii suppressed both growth and biofilm formation, behaviors which are correlated with disease susceptibility. Furthermore, in microfluidic chambers X. fastidiosa formed thick mature biofilm with three-dimensional (3-D structures, such as pillars and mounds, in saps from all susceptible spp. In contrast, only small aggregates of various shapes were formed in saps from four out of five of the resistant spp.; sap from the resistant spp. V. mustangensis was an exception in that it also supported thick lawns of biofilm but not the above described 3-D structures typically seen in a mature biofilm from the susceptible saps. Our findings provide not only critical technical information for future bioassays, but also suggest further understanding of PD susceptibility.

  14. Correlation of maple sap composition with bacterial and fungal communities determined by multiplex automated ribosomal intergenic spacer analysis (MARISA).

    Science.gov (United States)

    Filteau, Marie; Lagacé, Luc; LaPointe, Gisèle; Roy, Denis

    2011-08-01

    During collection, maple sap is contaminated by bacteria and fungi that subsequently colonize the tubing system. The bacterial microbiota has been more characterized than the fungal microbiota, but the impact of both components on maple sap quality remains unclear. This study focused on identifying bacterial and fungal members of maple sap and correlating microbiota composition with maple sap properties. A multiplex automated ribosomal intergenic spacer analysis (MARISA) method was developed to presumptively identify bacterial and fungal members of maple sap samples collected from 19 production sites during the tapping period. Results indicate that the fungal community of maple sap is mainly composed of yeast related to Mrakia sp., Mrakiella sp., Guehomyces pullulans, Cryptococcus victoriae and Williopsis saturnus. Mrakia, Mrakiella and Guehomyces peaks were identified in samples of all production sites and can be considered dominant and stable members of the fungal microbiota of maple sap. A multivariate analysis based on MARISA profiles and maple sap chemical composition data showed correlations between Candida sake, Janthinobacterium lividum, Williopsis sp., Leuconostoc mesenteroides, Mrakia sp., Rhodococcus sp., Pseudomonas tolaasii, G. pullulans and maple sap composition at different flow periods. This study provides new insights on the relationship between microbial community and maple sap quality. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. [Stem sap flow and water consumption of Tamarix ramosissima in hinterland of Taklimakan Desert].

    Science.gov (United States)

    Xu, Hao; Zhang, Xi-Ming; Yan, Hai-Long; Yao, Shi-Jun

    2007-04-01

    From April to November 2005, the stem sap flow and water consumption of Tamarix ramosissima in the hinterland of Taklimakan Desert was measured by Flow-32 System. The results showed that, in the extremely arid hinterland of Taklimakan Desert and under enough water supply, the average daily water consumption of T. ramosissima with a stem diameter of 3.5 cm and 2.0 cm was 6.322 kg and 1.179 kg, respectively in one growth season. The stem sap flow of T. ramosissima presented a single-peaked curve, with an obvious day and night variation rhythm and fluctuated with environment factors. Under enough water supply, the environmenal factors such as total radiation, wind speed and air temperature were the main factors affecting the stem sap flow, and the dynamics of stem sap flow could be predicted by the liner regression model based on total radiation and wind speed. Because of the extremely arid environment and enough water supply, T. ramosissima had a relatively higher stem sap flow rate and a great water consumption.

  16. Symbiotic maple saps minimize disruption of the mice intestinal microbiota after oral antibiotic administration.

    Science.gov (United States)

    Hammami, Riadh; Ben Abdallah, Nour; Barbeau, Julie; Fliss, Ismail

    2015-01-01

    This study was undertaken to evaluate the in vivo impact of new symbiotic products based on liquid maple sap or its concentrate. Sap and concentrate, with or without inulin (2%), were inoculated with Bifidobacterium lactis Bb12 and Lactobacillus rhamnosus GG valio at initial counts of 2-4 × 10(8) cfu mL(-1). The experiments started with intra-gastric administration of antibiotic (kanamycin 40 mg in 0.1 cc) (to induce microbiota disturbance and/or diarrhea) to 3-to-5-week-old C57BL/6 female mice followed by a combination of prebiotic and probiotics included in the maple sap or its concentrate for a week. The combination inulin and probiotics in maple sap and concentrate appeared to minimize the antibiotic-induced breakdown of mice microbiota with a marked effect on bifidobacterium and bacteroides levels, thus permitting a more rapid re-establishment of the baseline microbiota levels. Results suggest that maple sap and its concentrate represent good candidates for the production of non-dairy functional foods.

  17. Ethanol fermentation by the thermotolerant yeast, Kluyveromyces marxianus TISTR5925, of extracted sap from old oil palm trunk

    Directory of Open Access Journals (Sweden)

    Yoshinori Murata

    2015-05-01

    Full Text Available Palm sap extracted from old oil palm trunks was previously found to contain sugar and nutrients (amino acids and vitamins. Some palm saps contain a low content of sugar due to differences in species or in plant physiology. Here we condensed palm sap with a low content of sugar using flat membrane filtration, then fermented the condensed palm sap at high temperature using the thermotolerant, high ethanol-producing yeast, Kluyveromyces marxianus. Ethanol production under non-optimum conditions was evaluated. Furthermore, the energy required to concentrate the palm sap, and the amount of energy that could be generated from the ethanol, was calculated. The condensation of sugar in sap from palm trunk required for economically viable ethanol production was evaluated.

  18. [Dynamics of sap flow density in stems of typical desert shrub Calligonum mongolicum and its responses to environmental variables].

    Science.gov (United States)

    Xu, Shi-qin; Ji, Xi-bin; Jin, Bo-wen

    2016-02-01

    Independent measurements of stem sap flow in stems of Calligonum mongolicum and environmental variables using commercial sap flow gauges and a micrometeorological monitoring system, respectively, were made to simulate the variation of sap flow density in the middle range of Hexi Corridor, Northwest China during June to September, 2014. The results showed that the diurnal process of sap flow density in C. mongolicum showed a broad unimodal change, and the maximum sap flow density reached about 30 minutes after the maximum of photosynthetically active radiation (PAR) , while about 120 minutes before the maximum of temperature and vapor pressure deficit (VPD). During the studying period, sap flow density closely related with atmosphere evapor-transpiration demand, and mainly affected by PAR, temperature and VPD. The model was developed which directly linked the sap flow density with climatic variables, and good correlation between measured and simulated sap flow density was observed in different climate conditions. The accuracy of simulation was significantly improved if the time-lag effect was taken into consideration, while this model underestimated low and nighttime sap flow densities, which was probably caused by plant physiological characteristics.

  19. Tree water storage and its diurnal dynamics related to sap flow and changes in stem volume in old-growth Douglas-fir trees.

    Science.gov (United States)

    Cermák, Jan; Kucera, Jiri; Bauerle, William L; Phillips, Nathan; Hinckley, Thomas M

    2007-02-01

    Diurnal and seasonal tree water storage was studied in three large Douglas-fir (Pseudotsuga menziesii [Mirb.] Franco) trees at the Wind River Canopy Crane Research site. Changes in water storage were based on measurements of sap flow and changes in stem volume and tissue water content at different heights in the stem and branches. We measured sap flow by two variants of the heat balance method (with internal heating in stems and external heating in branches), stem volume with electronic dendrometers, and tissue water content gravimetrically. Water storage was calculated from the differences in diurnal courses of sap flow at different heights and their integration. Old-growth Douglas-fir trees contained large amounts of free water: stem sapwood was the most important storage site, followed by stem phloem, branch sapwood, branch phloem and needles. There were significant time shifts (minutes to hours) between sap flow measured at different positions within the transport system (i.e., stem base to shoot tip), suggesting a highly elastic transport system. On selected fine days between late July and early October, when daily transpiration ranged from 150 to 300 liters, the quantity of stored water used daily ranged from 25 to 55 liters, i.e., about 20% of daily total sap flow. The greatest amount of this stored water came from the lower stem; however, proportionally more water was removed from the upper parts of the tree relative to their water storage capacity. In addition to lags in sap flow from one point in the hydrolic pathway to another, the withdrawal and replacement of stored water was reflected in changes in stem volume. When point-to-point lags in sap flow (minutes to hours near the top and stem base, respectively) were considered, there was a strong linear relationship between stem volume changes and transpiration. Volume changes of the whole tree were small (equivalent to 14% of the total daily use of stored water) indicating that most stored water came from

  20. Predictive models for radial sap flux variation in coniferous, diffuse-porous and ring-porous temperate trees.

    Science.gov (United States)

    Berdanier, Aaron B; Miniat, Chelcy F; Clark, James S

    2016-08-01

    Accurately scaling sap flux observations to tree or stand levels requires accounting for variation in sap flux between wood types and by depth into the tree. However, existing models for radial variation in axial sap flux are rarely used because they are difficult to implement, there is uncertainty about their predictive ability and calibration measurements are often unavailable. Here we compare different models with a diverse sap flux data set to test the hypotheses that radial profiles differ by wood type and tree size. We show that radial variation in sap flux is dependent on wood type but independent of tree size for a range of temperate trees. The best-fitting model predicted out-of-sample sap flux observations and independent estimates of sapwood area with small errors, suggesting robustness in the new settings. We develop a method for predicting whole-tree water use with this model and include computer code for simple implementation in other studies. Published by Oxford University Press 2016. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  1. Environmental controls on sap flow in black locust forest in Loess Plateau, China.

    Science.gov (United States)

    Ma, Changkun; Luo, Yi; Shao, Mingan; Li, Xiangdong; Sun, Lin; Jia, Xiaoxu

    2017-10-13

    Black locust accounts for over 90% of artificial forests in China's Loess Plateau region. However, water use of black locust is an uphill challenge for this semi-arid region. To accurately quantify tree water use and to explain the related hydrological processes, it is important to collect reliable data for application in the estimation of sap flow and its response to environmental factors. This study measured sap flow in black locust in the 2015 and 2016 growth seasons using the thermal dissipation probes technique and laboratory-calibrated Granier's equation. The study showed that the laboratory calibrated coefficient α was much larger than the original value presented by Granier, while the coefficient β was similar to the original one. The average daily transpiration was 2.1 mm day -1 for 2015 and 1.6 mm day -1 for 2016. Net solar radiation (Rn) was the key meteorological factor controlling sap flow, followed by vapor pressure deficit (VPD) and then temperature (T). VPD had a threshold control on sap flow at threshold values of 1.9 kPa for 2015 and 1.6 kPa for 2016. The effects of diurnal hysteresis of Rn, VPD and T on sap flow were evident, indicating that black locust water use was conservative.

  2. Arsenate impact on the metabolite profile, production and arsenic loading of xylem sap in cucumbers (Cucumis sativus L.

    Directory of Open Access Journals (Sweden)

    Kalle eUroic

    2012-04-01

    Full Text Available Arsenic uptake and translocation studies on xylem sap focus generally on the concentration and speciation of arsenic in the xylem. Arsenic impact on the xylem sap metabolite profile and its production during short term exposure has not been reported in detail. To investigate this, cucumbers were grown hydroponically and arsenate (AsV and DMA were used for plant treatment for 24 h. Total arsenic and arsenic speciation in xylem sap was analysed including a metabolite profiling under arsenate stress. Produced xylem sap was quantified and absolute arsenic transported was determined. AsV exposure has a significant impact on the metabolite profile of xylem sap. Four m/z values corresponding to four compounds were up regulated, one compound down regulated by arsenate exposure. The compound down regulated was identified to be isoleucine. Furthermore, arsenate has a significant influence on sap production, leading to a reduction of up to 96 % sap production when plants are exposed to 1000 μg kg-1 arsenate. No difference to control plants was observed when plants were exposed to 1000 μg kg-1 DMA. Absolute arsenic amount in xylem sap was the lowest at high arsenate exposure. These results show that AsV has a significant impact on the production and metabolite profile of xylem sap. The physiological importance of isoleucine needs further attention.

  3. Arsenate Impact on the Metabolite Profile, Production, and Arsenic Loading of Xylem Sap in Cucumbers (Cucumis sativus L.)

    Science.gov (United States)

    Uroic, M. Kalle; Salaün, Pascal; Raab, Andrea; Feldmann, Jörg

    2012-01-01

    Arsenic uptake and translocation studies on xylem sap focus generally on the concentration and speciation of arsenic in the xylem. Arsenic impact on the xylem sap metabolite profile and its production during short term exposure has not been reported in detail. To investigate this, cucumbers were grown hydroponically and arsenate (AsV) and DMA were used for plant treatment for 24 h. Total arsenic and arsenic speciation in xylem sap was analyzed including a metabolite profiling under AsV stress. Produced xylem sap was quantified and absolute arsenic transported was determined. AsV exposure had a significant impact on the metabolite profile of xylem sap. Four m/z values corresponding to four compounds were up-regulated, one compound down-regulated by AsV exposure. The compound down-regulated was identified to be isoleucine. Furthermore, AsV exposure had a significant influence on sap production, leading to a reduction of up to 96% sap production when plants were exposed to 1000 μg kg−1 AsV. No difference to control plants was observed when plants were exposed to 1000 μg kg−1 DMA. Absolute arsenic amount in xylem sap was the lowest at high AsV exposure. These results show that AsV has a significant impact on the production and metabolite profile of xylem sap. The physiological importance of isoleucine needs further attention. PMID:22536187

  4. Microvillus-Specific Protein Tyrosine Phosphatase SAP-1 Plays a Role in Regulating the Intestinal Paracellular Transport of Macromolecules.

    Science.gov (United States)

    Mori, Shingo; Kamei, Noriyasu; Murata, Yoji; Takayama, Kozo; Matozaki, Takashi; Takeda-Morishita, Mariko

    2017-09-01

    The stomach cancer-associated protein tyrosine phosphatase 1 (SAP-1) is a receptor-type protein tyrosine phosphatase that is specifically expressed on the apical membrane of the intestinal epithelium. SAP-1 is known to maintain the balance of phosphorylation of proteins together with protein kinases; however, its biological function and impact on pharmacokinetics in the intestine remain unclear. The present study, therefore, aimed at clarifying the relationship between SAP-1 and the intestinal absorption behaviors of typical transporter substrates and macromolecules. The endogenous levels of glucose and total cholesterol in the blood were similar between wild-type and SAP-1-deficient mice (Sap1 -/- ), suggesting no contribution of SAP-1 to biogenic influx. Moreover, in vitro transport study with everted ileal sacs demonstrated that there was no difference in the absorption of breast cancer resistance protein, P-glycoprotein, and peptide transporter substrates between both mice. However, absorptive clearance of macromolecular model dextrans (FD-4 and FD-10) in Sap1 -/- mice was significantly higher than that in wild-type mice, and this was confirmed by the trend of increased FD-4 absorption from colonic loops of Sap1 -/- mice. Therefore, the results of this study suggest the partial contribution of SAP-1 to the regulated transport of hydrophilic macromolecules through paracellular tight junctions. Copyright © 2017 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.

  5. Effects on functional groups and zeta potential of SAP1pulsed electric field technology.

    Science.gov (United States)

    Liang, Rong; Li, Xuenan; Lin, Songyi; Wang, Jia

    2017-01-01

    SAP 1 pulsed electric field (PEF) technology. The effects of electric field intensity and pulse frequency on SAP 1 electric field intensity 15 kV cm -1 , pulse frequency 1600 Hz and flow velocity 2.93 mL min -1 ). Furthermore, the PEF-treated SAP 1 < MW < 3kDa under optimal conditions lacked the characteristic absorbance of N-H, C = C and the amide band and the zeta potential was reduced to -18.0 mV. Overall, the results of the present study suggest that the improvement of antioxidant activity of SAP 1 < MW < 3kDa is a result of the contribution of the functional groups and the change in zeta potential when treated with PEF. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  6. Euler European Libraries and Electronic Resources in Mathematical Sciences

    CERN Document Server

    The Euler Project. Karlsruhe

    The European Libraries and Electronic Resources (EULER) Project in Mathematical Sciences provides the EulerService site for searching out "mathematical resources such as books, pre-prints, web-pages, abstracts, proceedings, serials, technical reports preprints) and NetLab (for Internet resources), this outstanding engine is capable of simple, full, and refined searches. It also offers a browse option, which responds to entries in the author, keyword, and title fields. Further information about the Project is provided at the EULER homepage.

  7. 49 CFR 40.307 - What is the SAP's function in prescribing the employee's follow-up tests?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What is the SAP's function in prescribing the... the Return-to-Duty Process § 40.307 What is the SAP's function in prescribing the employee's follow-up tests? (a) As a SAP, for each employee who has committed a DOT drug or alcohol regulation violation, and...

  8. Circadian patterns of xylem sap properties and their covariation with plant hydraulic traits in hybrid aspen.

    Science.gov (United States)

    Meitern, Annika; Õunapuu-Pikas, Eele; Sellin, Arne

    2017-06-01

    Physiological processes taking place in plants are subject to diverse circadian patterns but some of them are poorly documented in natural conditions. The daily dynamics of physico-chemical properties of xylem sap and their covariation with tree hydraulic traits were investigated in hybrid aspen (Populus tremula L.×P. tremuloides Michx) in field conditions in order to clarify which environmental drivers govern the daily variation in these parameters. K + concentration ([K + ]), electrical conductivity (σ sap ), osmolality (Osm) and pH of the xylem sap, as well as branch hydraulic traits, were measured in the field over 24-h cycles. All studied xylem sap properties and hydraulic characteristics including whole-branch (K wb ), leaf blade (K lb ) and petiole hydraulic conductances (K P ) showed clear daily dynamics. Air temperature (T A ) and photosynthetic photon flux density (PPFD), but also water vapour pressure deficit (VPD) and relative humidity (RH), had significant impacts on K wb K lb , K P , [K + ] and σ sap . Osm varied only with light intensity, while K B varied depending on atmospheric evaporative demand expressed as T A , VPD or RH. Xylem sap pH depended inversely on soil water potential (Ψ S ) and during daylight also on VPD. Although soil water content was close to saturation during the study period, Ψ S influenced also [K + ] and σ sap . The present study presents evidence of coupling between circadian patterns of xylem sap properties and plant hydraulic conductance providing adequate water supply to foliage under environmental conditions characterised by diurnal variation. Copyright © 2017 Elsevier GmbH. All rights reserved.

  9. Enhancement of crack healing efficiency and performance of SAP in biocrete

    Science.gov (United States)

    Giriselvam, M. G.; Poornima, V.; Venkatasubramani, R.; Sreevidya, V.

    2018-02-01

    Concrete usage in Construction becomes more common in this speedy world. Despite its benefits, concrete often exhibits crack which appear due to stresses. Larger cracks cause Structural integrity problems and smaller cracks may result in durability issues. A novel environmental friendly strategy to restore or remediate cracks formed in the structures is bio-mineralization of calcium carbonate using microbes such as Bacillus Subtilis (used in this study), as manual repair and maintenance is costly. In this Paper, an idea of using Super Absorbent Polymer in Bacterial Concrete was analysed which increases the strength and durability properties of concrete and also which acts as a protection to bacteria, where Self-Healing nature is viewed. In the span of 90 days, the results of Bacterial concrete cured under normal water providing nutrients inside with SAP shows healing up to 74 % and without SAP displays 49 % and when it is cured under nutrient medium, Bacterial Concrete having SAP displays healing up to 66 %, whereas without SAP it displays 57.4% of healing. During the observation it is discernible that the crack width ranging from 0.10 mm near 0.45 mm show better self-healing capacity. XRD analysis displays the presence of Calcium carbonate precipitation in cracks.

  10. Effects of Electronic Information Resources Skills Training for Lecturers on Pedagogical Practices and Research Productivity

    Science.gov (United States)

    Bhukuvhani, Crispen; Chiparausha, Blessing; Zuvalinyenga, Dorcas

    2012-01-01

    Lecturers use various electronic resources at different frequencies. The university library's information literacy skills workshops and seminars are the main sources of knowledge of accessing electronic resources. The use of electronic resources can be said to have positively affected lecturers' pedagogical practices and their work in general. The…

  11. The performance and customization of SAPS 3 admission score in a Thai medical intensive care unit.

    Science.gov (United States)

    Khwannimit, Bodin; Bhurayanontachai, Rungsun

    2010-02-01

    The aim of this study was to evaluate the performance of Simplified Acute Physiology Score 3 (SAPS 3) admission scores, both the original and a customized version, in mixed medical critically ill patients. A prospective cohort study was conducted over a 2-year period in the medical intensive care unit (MICU) of a tertiary referral university teaching hospital in Thailand. The probability of hospital mortality of the original SAPS 3 was calculated using the general and customized Australasia version (SAPS 3-AUS). The patients were randomly divided into equal calibration and validation groups for customization. A total of 1,873 patients were enrolled. The hospital mortality rate was 28.6%. The general equation of SAPS 3 had excellent discrimination with an area under the receiver operating characteristic curve of 0.933, but poor calibration with the Hosmer-Lemeshow goodness-of-fit H = 106.7 and C = 101.2 (P customized SAPS 3 showed a good calibration of all patients in the validation group (H = 14, P = 0.17 and C = 11.3, P = 0.33) and all subgroups according to main diagnosis, age, gender and co-morbidities. The SAPS 3 provided excellent discrimination but poor calibration in our MICU. A first level customization of the SAPS 3 improved the calibration and could be used to predict mortality and quality assessment in our ICU or other ICUs with a similar case mix.

  12. Molecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP.

    Directory of Open Access Journals (Sweden)

    Umaimainthan Palendira

    2011-11-01

    Full Text Available X-linked lymphoproliferative disease (XLP is a primary immunodeficiency caused by mutations in SH2D1A which encodes SAP. SAP functions in signalling pathways elicited by the SLAM family of leukocyte receptors. A defining feature of XLP is exquisite sensitivity to infection with EBV, a B-lymphotropic virus, but not other viruses. Although previous studies have identified defects in lymphocytes from XLP patients, the unique role of SAP in controlling EBV infection remains unresolved. We describe a novel approach to this question using female XLP carriers who, due to random X-inactivation, contain both SAP(+ and SAP(- cells. This represents the human equivalent of a mixed bone marrow chimera in mice. While memory CD8(+ T cells specific for CMV and influenza were distributed across SAP(+ and SAP(- populations, EBV-specific cells were exclusively SAP(+. The preferential recruitment of SAP(+ cells by EBV reflected the tropism of EBV for B cells, and the requirement for SAP expression in CD8(+ T cells for them to respond to Ag-presentation by B cells, but not other cell types. The inability of SAP(- clones to respond to Ag-presenting B cells was overcome by blocking the SLAM receptors NTB-A and 2B4, while ectopic expression of NTB-A on fibroblasts inhibited cytotoxicity of SAP(- CD8(+ T cells, thereby demonstrating that SLAM receptors acquire inhibitory function in the absence of SAP. The innovative XLP carrier model allowed us to unravel the mechanisms underlying the unique susceptibility of XLP patients to EBV infection in the absence of a relevant animal model. We found that this reflected the nature of the Ag-presenting cell, rather than EBV itself. Our data also identified a pathological signalling pathway that could be targeted to treat patients with severe EBV infection. This system may allow the study of other human diseases where heterozygous gene expression from random X-chromosome inactivation can be exploited.

  13. A randomized controlled trial of interventions to impede date palm sap contamination by bats to prevent nipah virus transmission in Bangladesh.

    Directory of Open Access Journals (Sweden)

    Salah Uddin Khan

    Full Text Available BACKGROUND: Drinking raw date palm sap is a risk factor for human Nipah virus (NiV infection. Fruit bats, the natural reservoir of NiV, commonly contaminate raw sap with saliva by licking date palm's sap producing surface. We evaluated four types of physical barriers that may prevent bats from contacting sap. METHODS: During 2009, we used a crossover design and randomly selected 20 date palm sap producing trees and observed each tree for 2 nights: one night with a bamboo skirt intervention applied and one night without the intervention. During 2010, we selected 120 trees and randomly assigned four types of interventions to 15 trees each: bamboo, dhoincha (local plant, jute stick and polythene skirts covering the shaved part, sap stream, tap and collection pot. We enrolled the remaining 60 trees as controls. We used motion sensor activated infrared cameras to examine bat contact with sap. RESULTS: During 2009 bats contacted date palm sap in 85% of observation nights when no intervention was used compared with 35% of nights when the intervention was used [p<0.001]. Bats were able to contact the sap when the skirt did not entirely cover the sap producing surface. Therefore, in 2010 we requested the sap harvesters to use larger skirts. During 2010 bats contacted date palm sap [2% vs. 83%, p<0.001] less frequently in trees protected with skirts compared to control trees. No bats contacted sap in trees with bamboo (p<0.001 compared to control, dhoincha skirt (p<0.001 or polythene covering (p<0.001, but bats did contact sap during one night (7% with the jute stick skirt (p<0.001. CONCLUSION: Bamboo, dhoincha, jute stick and polythene skirts covering the sap producing areas of a tree effectively prevented bat-sap contact. Community interventions should promote applying these skirts to prevent occasional Nipah spillovers to human.

  14. Implantación de SAP ERP en una distribuidora

    OpenAIRE

    Martínez Costales, Guillermo

    2013-01-01

    En este trabajo se pretende reflejar en qué consistiría un proyecto de implantación de un ERP, en nuestro caso SAP ERP, en una empresa del sector de la distribución alimenticia. Para llevarlo a cabo se empleará la metodología ASAP, pretendiendo ser el resultado final del proyecto el análisis y diseño del mismo. En aquest treball es pretén reflectir en què consistiria un projecte d'implantació d'un ERP, en el nostre cas SAP ERP, en una empresa del sector de la distribució alimentària. Per f...

  15. Metabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease

    NARCIS (Netherlands)

    Lowe-Power, Tiffany M.; Hendrich, Connor G.; Roepenack-Lahaye, von Edda; Li, Bin; Wu, Dousheng; Mitra, Raka; Dalsing, Beth L.; Ricca, Patrizia; Naidoo, Jacinth; Cook, David; Jancewicz, Amy; Masson, Patrick; Thomma, Bart; Lahaye, Thomas; Michael, Anthony J.; Allen, Caitilyn

    2018-01-01

    Ralstonia solanacearum thrives in plant xylem vessels and causes bacterial wilt disease despite the low nutrient content of xylem sap. We found that R. solanacearum manipulates its host to increase nutrients in tomato xylem sap, enabling it to grow better in sap from infected plants than in sap from

  16. Estimates of evapotranspiration for riparian sites (Eucalyptus) in the Lower Murray -Darling Basin using ground validated sap flow and vegetation index scaling techniques

    Science.gov (United States)

    Doody, T.; Nagler, P. L.; Glenn, E. P.

    2014-12-01

    Water accounting is becoming critical globally, and balancing consumptive water demands with environmental water requirements is especially difficult in in arid and semi-arid regions. Within the Murray-Darling Basin (MDB) in Australia, riparian water use has not been assessed across broad scales. This study therefore aimed to apply and validate an existing U.S. riparian ecosystem evapotranspiration (ET) algorithm for the MDB river systems to assist water resource managers to quantify environmental water needs over wide ranges of niche conditions. Ground-based sap flow ET was correlated with remotely sensed predictions of ET, to provide a method to scale annual rates of water consumption by riparian vegetation over entire irrigation districts. Sap flux was measured at nine locations on the Murrumbidgee River between July 2011 and June 2012. Remotely sensed ET was calculated using a combination of local meteorological estimates of potential ET (ETo) and rainfall and MODIS Enhanced Vegetation Index (EVI) from selected 250 m resolution pixels. The sap flow data correlated well with MODIS EVI. Sap flow ranged from 0.81 mm/day to 3.60 mm/day and corresponded to a MODIS-based ET range of 1.43 mm/day to 2.42 mm/day. We found that mean ET across sites could be predicted by EVI-ETo methods with a standard error of about 20% across sites, but that ET at any given site could vary much more due to differences in aquifer and soil properties among sites. Water use was within range of that expected. We conclude that our algorithm developed for US arid land crops and riparian plants is applicable to this region of Australia. Future work includes the development of an adjusted algorithm using these sap flow validated results.

  17. The study of Cr(III) complexation in the xylem sap using ion exchange and radiotracer

    International Nuclear Information System (INIS)

    Juneja, Shikha; Prakash, Satya

    2003-01-01

    Radiotracer was employed to carry out ion exchange experiments to study the chromium speciation in the in vitro samples of xylem sap of maize stem of 60 days old plants. Cr(III) radiolabelled with its radioactive isotope ( 51 Cr) was mixed with both the ion exchange fraction of the sap which represented the carboxylic acids, as well as the whole sap and was analysed for complexation after 10 and 30 days at 25 degC. Prior to this, the ion exchange elution chromatography of Cr(III), and the Cr(III) complexes with oxalic and citric acid were used to compare the complexes being formed in the in vitro studies. The in vitro Cr(III) complexation results indicated that Cr(III) was vitally present as anionic species. The elution curve trend was similar to that of citric acid complexation. Citric acid was also found to be the major complexing acid in the xylem sap as determined by HPLC. The results indicate the transportation of Cr(III) as a citrate complex in the xylem sap of maize plants. (author)

  18. Logistic Core Operations with SAP Inventory Management, Warehousing, Transportation, and Compliance

    CERN Document Server

    Kappauf, Jens; Koch, Matthias

    2012-01-01

    “Logistic Core Operations with SAP” not only provides an overview of core logistics processes and functionality—it also shows how SAP’s Business Suite covers logistic core operations, what features are supported, and which systems can be used to implement end-to-end processes in the following logistic core disciplines: Procurement, Distribution, Transportation, Warehouse Logistics and Inventory Management, and Compliance and Reporting. In this context the authors not only explain their integration, the organizational set-up, and master data, but also which solution fits best for a particular business need.   This book serves as a solid foundation for understanding SAP software. No matter whether you are a student or a manager involved in an SAP implementation, the authors go far beyond traditional function and feature descriptions, helping you ask the right questions, providing answers, and making recommendations. The book assists you in understanding SAP terminology, concepts and technological compo...

  19. Affinity purification mass spectrometry analysis of PD-1 uncovers SAP as a new checkpoint inhibitor.

    Science.gov (United States)

    Peled, Michael; Tocheva, Anna S; Sandigursky, Sabina; Nayak, Shruti; Philips, Elliot A; Nichols, Kim E; Strazza, Marianne; Azoulay-Alfaguter, Inbar; Askenazi, Manor; Neel, Benjamin G; Pelzek, Adam J; Ueberheide, Beatrix; Mor, Adam

    2018-01-16

    Programmed cell death-1 (PD-1) is an essential inhibitory receptor in T cells. Antibodies targeting PD-1 elicit durable clinical responses in patients with multiple tumor indications. Nevertheless, a significant proportion of patients do not respond to anti-PD-1 treatment, and a better understanding of the signaling pathways downstream of PD-1 could provide biomarkers for those whose tumors respond and new therapeutic approaches for those whose tumors do not. We used affinity purification mass spectrometry to uncover multiple proteins associated with PD-1. Among these proteins, signaling lymphocytic activation molecule-associated protein (SAP) was functionally and mechanistically analyzed for its contribution to PD-1 inhibitory responses. Silencing of SAP augmented and overexpression blocked PD-1 function. T cells from patients with X-linked lymphoproliferative disease (XLP), who lack functional SAP, were hyperresponsive to PD-1 signaling, confirming its inhibitory role downstream of PD-1. Strikingly, signaling downstream of PD-1 in purified T cell subsets did not correlate with PD-1 surface expression but was inversely correlated with intracellular SAP levels. Mechanistically, SAP opposed PD-1 function by acting as a molecular shield of key tyrosine residues that are targets for the tyrosine phosphatase SHP2, which mediates PD-1 inhibitory properties. Our results identify SAP as an inhibitor of PD-1 function and SHP2 as a potential therapeutic target in patients with XLP.

  20. Electronic Commerce Resource Centers. An Industry--University Partnership.

    Science.gov (United States)

    Gulledge, Thomas R.; Sommer, Rainer; Tarimcilar, M. Murat

    1999-01-01

    Electronic Commerce Resource Centers focus on transferring emerging technologies to small businesses through university/industry partnerships. Successful implementation hinges on a strategic operating plan, creation of measurable value for customers, investment in customer-targeted training, and measurement of performance outputs. (SK)

  1. Dynamic Acquisition and Loss of Dual-Obligate Symbionts in the Plant-Sap-Feeding Adelgidae (Hemiptera: Sternorrhyncha: Aphidoidea)

    Science.gov (United States)

    Carol D. von Dohlen; Usha Spaulding; Kistie B. Patch; Kathryn M. Weglarz; Robert G. Foottit; Nathan P. Havill; Gaelen R. Burke

    2017-01-01

    Sap-sucking insects typically engage in obligate relationships with symbiotic bacteria that play nutritional roles in synthesizing nutrients unavailable or in scarce supply from the plant-sap diets of their hosts. Adelgids are sap-sucking insects with complex life cycles that involve alternation between conifer tree species. While all adelgid species feed on spruce...

  2. 78 FR 43091 - Technical Operations Safety Action Program (T-SAP) and Air Traffic Safety Action Program (ATSAP)

    Science.gov (United States)

    2013-07-19

    ... Administration 14 CFR Part 193 [Docket No.: FAA-2013-0375] Technical Operations Safety Action Program (T-SAP) and... Disclosure. SUMMARY: The FAA is proposing that safety information provided to it under the T-SAP, established... to the FAA under the T-SAP and ATSAP, so the FAA can learn about and address aviation safety hazards...

  3. Evaluación de los resultados de implementación de proyectos de tecnología de información ERP SAP, en grandes empresas del Área Metropolitana de Medellín

    OpenAIRE

    Vélez Maya, Jhon Jairo; Arango Uribe, Diana Milena

    2010-01-01

    En los últimos años, algunas de las grandes empresas del área metropolitana de Medellín, decidieran adquirir e implementar sistemas ERP (Enterprise Resource Planning) SAP. Los proyectos de implementación de un ERP SAP, son complejos, toman mucho tiempo y exigen la asignación de importantes recursos humanos y económicos. En esta investigación se evalúan los resultados obtenidos por algunas de estas empresas, así como los factores que a juicio de las personas consultadas en cada empresa, incide...

  4. 49 CFR 40.293 - What is the SAP's function in conducting the initial evaluation of an employee?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What is the SAP's function in conducting the... Professionals and the Return-to-Duty Process § 40.293 What is the SAP's function in conducting the initial evaluation of an employee? As a SAP, for every employee who comes to you following a DOT drug and alcohol...

  5. 49 CFR 40.301 - What is the SAP's function in the follow-up evaluation of an employee?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What is the SAP's function in the follow-up... the Return-to-Duty Process § 40.301 What is the SAP's function in the follow-up evaluation of an employee? (a) As a SAP, after you have prescribed assistance under § 40.293, you must re-evaluate the...

  6. Effects of Acer okamotoanum sap on the function of polymorphonuclear neutrophilic leukocytes in vitro and in vivo.

    Science.gov (United States)

    An, Beum-Soo; Kang, Ji-Houn; Yang, Hyun; Yang, Mhan-Pyo; Jeung, Eui-Bae

    2013-02-01

    Sap is a plant fluid that primarily consists of water and small amounts of mineral elements, sugars, hormones and other nutrients. Acer mono (A. mono) is an endemic Korean mono maple which was recently suggested to have health benefits due to its abundant calcium and magnesium ion content. In the present study, we examined the effects of sap from Acer okamotoanum (A. okamotoanum) on the phagocytic response of mouse neutrophils in vivo and rat and canine neutrophils in vitro. We tested the regulation of phagocytic activity, oxidative burst activity (OBA) and the levels of filamentous polymeric actin (F-actin) in the absence and presence of dexamethasone (DEX) in vitro and in vivo. Our results showed that DEX primarily reduced OBA in the mouse neutrophils, and that this was reversed in the presence of the sap. By contrast, the phagocytic activity of the mouse cells was not regulated by either DEX or the sap. Rat and canine polymorphonuclear neutrophilic leukocytes (PMNs) responded in vitro to the sap in a similar manner by increasing OBA. However, regulation of phagocytic activity by the sap was different between the species. In canine PMNs, phagocytic activity was enhanced by the sap at a high dose, while it did not significantly modulate this activity in rat PMNs. These findings suggest that the sap of A. okamotoanum stimulates neutrophil activity in the mouse, rat and canine by increasing OBA in vivo and in vitro, and thus may have a potential antimicrobial effect in the PMNs of patients with infections.

  7. Pengaruh Pemahaman Standar Akuntansi Pemerintahan (SAP, Pelatihan, Akuntabilitas, Transparansi Terhadap Penyusunan Laporan Keuangan SKPD Kota Padangsidimpuan

    OpenAIRE

    Daulay, Putri Bunga Meiliana

    2016-01-01

    This skripsi is intended to (a) get a clear view about the effect of understanding SAP, training, accountability, tranparancy (b) calculate the effect of understanding SAP, training, accountability, transparancy to the way of making financial statement, (c) give some advices which may assist the City Government in solving its problems especially the discussed problem, that is the way of making financial statement which is affected by understanding SAP, training, accountability, transparancy. ...

  8. Recovery of tritium from lithium-sintered aluminium product (SAP) and lithium-aluminium alloys

    International Nuclear Information System (INIS)

    Talbot, J.B.; Wiffen, F.W.

    1979-01-01

    The tritium release rates of irradiated samples of lithium-containing aluminium (Li-Al) and sintered aluminium product (Li-SAP) were investigated to evaluate the potential application of both materials in fusion reactors. The observed release rates followed the pattern expected for bulk diffusion of tritium in a solid. Therefore, diffusion coefficients for tritium in Li-SAP were determined over a temperature range of 383 and 500 0 C and tritium in Li-Al at 450 0 C. At 450 0 C, the diffusion coefficients of tritium in Li-SAP and Li-Al are 2.988 x 10 -10 cm 2 sec -1 and 1.462 x 10 -6 cm 2 sec -1 , respectively. (author)

  9. A Randomized Controlled Trial of Interventions to Impede Date Palm Sap Contamination by Bats to Prevent Nipah Virus Transmission in Bangladesh

    Science.gov (United States)

    Khan, Salah Uddin; Gurley, Emily S.; Hossain, M. Jahangir; Nahar, Nazmun; Sharker, M. A. Yushuf; Luby, Stephen P.

    2012-01-01

    Background Drinking raw date palm sap is a risk factor for human Nipah virus (NiV) infection. Fruit bats, the natural reservoir of NiV, commonly contaminate raw sap with saliva by licking date palm’s sap producing surface. We evaluated four types of physical barriers that may prevent bats from contacting sap. Methods During 2009, we used a crossover design and randomly selected 20 date palm sap producing trees and observed each tree for 2 nights: one night with a bamboo skirt intervention applied and one night without the intervention. During 2010, we selected 120 trees and randomly assigned four types of interventions to 15 trees each: bamboo, dhoincha (local plant), jute stick and polythene skirts covering the shaved part, sap stream, tap and collection pot. We enrolled the remaining 60 trees as controls. We used motion sensor activated infrared cameras to examine bat contact with sap. Results During 2009 bats contacted date palm sap in 85% of observation nights when no intervention was used compared with 35% of nights when the intervention was used [psap when the skirt did not entirely cover the sap producing surface. Therefore, in 2010 we requested the sap harvesters to use larger skirts. During 2010 bats contacted date palm sap [2% vs. 83%, psap in trees with bamboo (psap during one night (7%) with the jute stick skirt (psap producing areas of a tree effectively prevented bat-sap contact. Community interventions should promote applying these skirts to prevent occasional Nipah spillovers to human. PMID:22905160

  10. Piloting the use of indigenous methods to prevent Nipah virus infection by interrupting bats' access to date palm sap in Bangladesh.

    Science.gov (United States)

    Nahar, Nazmun; Mondal, Utpal Kumar; Sultana, Rebeca; Hossain, M Jahangir; Khan, M Salah Uddin; Gurley, Emily S; Oliveras, Elizabeth; Luby, Stephen P

    2013-09-01

    People in Bangladesh frequently drink fresh date palm sap. Fruit bats (Pteropus giganteus) also drink raw sap and may contaminate the sap by shedding Nipah virus through saliva and urine. In a previous study we identified two indigenous methods to prevent bats accessing the sap, bamboo skirts and lime (calcium carbonate). We conducted a pilot study to assess the acceptability of these two methods among sap harvesters. We used interactive community meetings and group discussions to encourage all the sap harvesters (n = 12) from a village to use either bamboo skirts or lime smear that some of them (n = 4) prepared and applied. We measured the preparation and application time and calculated the cost of bamboo skirts. We conducted interviews after the use of each method. The sap harvesters found skirts effective in preventing bats from accessing sap. They were sceptical that lime would be effective as the lime was washed away by the sap flow. Preparation of the skirt took ∼105 min. The application of each method took ∼1 min. The cost of the bamboo skirt is minimal because bamboo is widely available and they made the skirts with pieces of used bamboo. The bamboo skirt method appeared practical and affordable to the sap harvesters. Further studies should explore its ability to prevent bats from accessing date palm sap and assess if its use produces more or better quality sap, which would provide further incentives to make it more acceptable for its regular use.

  11. Mechanical properties of concrete with SAP. Part II: Modulus of elasticity

    DEFF Research Database (Denmark)

    Hasholt, Marianne Tange; Jespersen, Morten H. Seneka; Jensen, Ole Mejlhede

    2010-01-01

    In this study, focus is on the modulus of elasticity for concrete with superabsorbent polymers (SAP). The results show that based on composite theory it is possible to establish a model, which predicts overall concrete elasticity. The model assumes a three phase material of aggregate, cement paste......, and air with volume fractions of the three phases as well as elastic properties of paste and aggregates as input parameters. Addition of SAP changes the E-modulus, because it both has an influence on properties of the cement paste and on the volume of air voids. Here, the E-modulus is an example...... a more or less empirical relation. The results show that when introducing SAP, models of a more empirical nature can be misleading (and e.g. relations stated in codes are often of this empirical nature). The reason is twofold: First, the empirical models often have a general problem with the effect...

  12. Selection of the best consultant for SAP ERP project using combined AHP-IBA approach

    Directory of Open Access Journals (Sweden)

    Martinović Nataša

    2014-01-01

    Full Text Available In this paper we propose a combined AHP-IBA model for selecting the best SAP consultant for an SAP ERP project. The goal of the SAP Project Manager is to choose the best consultant, the one who is able to implement standard SAP functionalities with quality and on time. When making a decision on the basis of multiple criteria, the traditional Analytic Hierarchy Process (AHP method does not take into account the fact that attributes may correlate, assuming that there are no dependencies between them. However, the dependencies of the attributes can often be used to model important knowledge for multiple criteria decision analysis. We propose an extension to the traditional AHP method by applying Interpolative realization of Boolean algebra (IBA, using AHP to determine the criteria weights, and IBA to model the logical interactions among criteria. The research conducted on ERP consultant selection suggests that the decision making process is modelled more accurately if logical interactions between attributes are modelled before applying AHP.

  13. Sexual Abuse Prevention Mobile Application (SAP_MobAPP) for Primary School Children in Korea.

    Science.gov (United States)

    Moon, Kyoung Ja; Park, Kyung Min; Sung, Yunsick

    2017-07-01

    This study aimed to develop and evaluate the effects of a sexual abuse prevention mobile application, SAP_MobAPP, for primary school children. Forty-five subjects were trained for 40 minutes once a week. The experimental group received education that utilized the SAP_MobAPP. Control group A received Web based sexual abuse prevention education, while control group B received textbook based sexual abuse prevention education. Effectiveness was verified through a survey on child sexual abuse recognition and avoidance skills administered before and after training. The SAP_MobAPP program improved recognition (awareness) and the child's skills to avoid child sexual abuse situations, and the effects were long-lasting. However, differences between groups were not statistically significant. This study developed a sexual abuse prevention application and verified its effectiveness. Awareness and skills to avoid child sexual abuse after app education increased immediately after training and four weeks later. The SAP_MobAPP could be used for sexual abuse prevention education in schools.

  14. Genetic variability of the phloem sap metabolite content of maize (Zea mays L.) during the kernel-filling period.

    Science.gov (United States)

    Yesbergenova-Cuny, Zhazira; Dinant, Sylvie; Martin-Magniette, Marie-Laure; Quilleré, Isabelle; Armengaud, Patrick; Monfalet, Priscilla; Lea, Peter J; Hirel, Bertrand

    2016-11-01

    Using a metabolomic approach, we have quantified the metabolite composition of the phloem sap exudate of seventeen European and American lines of maize that had been previously classified into five main groups on the basis of molecular marker polymorphisms. In addition to sucrose, glutamate and aspartate, which are abundant in the phloem sap of many plant species, large quantities of aconitate and alanine were also found in the phloem sap exudates of maize. Genetic variability of the phloem sap composition was observed in the different maize lines, although there was no obvious relationship between the phloem sap composition and the five previously classified groups. However, following hierarchical clustering analysis there was a clear relationship between two of the subclusters of lines defined on the basis of the composition of the phloem sap exudate and the earliness of silking date. A comparison between the metabolite contents of the ear leaves and the phloem sap exudates of each genotype, revealed that the relative content of most of the carbon- and nitrogen-containing metabolites was similar. Correlation studies performed between the metabolite content of the phloem sap exudates and yield-related traits also revealed that for some carbohydrates such as arabitol and sucrose there was a negative or positive correlation with kernel yield and kernel weight respectively. A posititive correlation was also found between kernel number and soluble histidine. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. SAP BusinessObjects Dashboards 4.1 cookbook

    CERN Document Server

    Lai, David

    2015-01-01

    If you are a developer with a good command and knowledge of creating dashboards, but are not yet an advanced user of SAP BusinessObjects Dashboards, then this is the perfect book for you. Prerequisites include a good working knowledge of Microsoft Excel as well as knowledge of basic dashboard practices.

  16. Seasonal and diel variation in xylem CO2 concentration and sap pH in sub-Mediterranean oak stems.

    Science.gov (United States)

    Salomón, Roberto; Valbuena-Carabaña, María; Teskey, Robert; McGuire, Mary Anne; Aubrey, Doug; González-Doncel, Inés; Gil, Luis; Rodríguez-Calcerrada, Jesús

    2016-04-01

    Since a substantial portion of respired CO2 remains within the stem, diel and seasonal trends in stem CO2 concentration ([CO2]) are of major interest in plant respiration and carbon budget research. However, continuous long-term stem [CO2] studies are scarce, and generally absent in Mediterranean climates. In this study, stem [CO2] was monitored every 15min together with stem and air temperature, sap flow, and soil water storage during a growing season in 16 stems of Quercus pyrenaica to elucidate the main drivers of stem [CO2] at different temporal scales. Fluctuations in sap pH were also assessed during two growing seasons to evaluate potential errors in estimates of the concentration of CO2 dissolved in xylem sap ([CO2*]) calculated using Henry's law. Stem temperature was the best predictor of stem [CO2] and explained more than 90% and 50% of the variability in stem [CO2] at diel and seasonal scales, respectively. Under dry conditions, soil water storage was the main driver of stem [CO2]. Likewise, the first rains after summer drought caused intense stem [CO2] pulses, suggesting enhanced stem and root respiration and increased resistance to radial CO2 diffusion. Sap flow played a secondary role in controlling stem [CO2] variations. We observed night-time sap pH acidification and progressive seasonal alkalinization. Thus, if the annual mean value of sap pH (measured at midday) was assumed to be constant, night-time sap [CO2*] was substantially overestimated (40%), and spring and autumn sap [CO2*] were misestimated by 25%. This work highlights that diel and seasonal variations in temperature, tree water availability, and sap pH substantially affect xylem [CO2] and sap [CO2*]. © The Author 2016. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  17. Combination of Successive Alkalinity Producing System (SAPS) and Aeration for Passive Treatment of Highly Acidic Mine Drainage

    Science.gov (United States)

    Oh, C.; Ji, S.

    2015-12-01

    Passive treatment system has been widely used for remediation of mine drainage since its advantage of low installation and maintenance cost. The system, however, has also a disadvantage in assuring remediation and management efficiency if the drainage is highly acidic mine drainage. To remediate acid mine drainage (AMD) especially showing high acidity, passive treatment system which consists of successive alkalinity producing system (SAPS) and subsequent aeration pond was proposed and its mechanisms and efficiency was evaluated in this research. Target AMD was obtained from Waryong coal mine and showed typical characteristics of AMD having high metal concentration and low pH (acidity > 300 mg/L as CaCO3). Four experimental cases were conducted; untreated, treated with SAPS, treated with aeration, treated with SAPS and aeration to compare role and mechanism of each unit. Between organic matter and limestone layer which constitute SAPS, the former eliminated most of Fe(III) and Al in the AMD so that the latter was kept from being clogged by precipitates. Net acidity of the AMD rapidly decreased by supplement of alkalinity at the limestone layer. A primary function of SAPS, producing alkalinity constantly without clogging, was attained due to addition a portion of limestone particle into the organic matter layer. The discharge from SAPS had low ORP and DO values because of an anaerobic environment formed at the organic matter layer although its alkalinity was increased. This water quality was unfavorable for Fe(II) to be oxidized. Installation of aeration pond after SAPS, therefore, could be effective way of enhancing oxidation rate of Fe(II). Among the experimental cases, the combination of SAPS and aeration pond was only able to remediate the AMD. This concluded that to remediate highly acidic mine drainage with passive treatment system, three critical conditions were required; pre-precipitation of Fe(III) and Al at organic matter layer in SAPS, constant alkalinity

  18. 78 FR 12676 - Timing Requirements for the Submission of a Site Assessment Plan (SAP) or General Activities Plan...

    Science.gov (United States)

    2013-02-25

    ...: BOEM-2012-0077] RIN 1010-AD77 Timing Requirements for the Submission of a Site Assessment Plan (SAP) or... would amend the timing requirements for submitting a Site Assessment Plan (SAP) or General Activities... and grants will have a preliminary term of 12 months in which a lessee or grantee must submit a SAP or...

  19. Proteomics approach to identify unique xylem sap proteins in Pierce's disease-tolerant Vitis species.

    Science.gov (United States)

    Basha, Sheikh M; Mazhar, Hifza; Vasanthaiah, Hemanth K N

    2010-03-01

    Pierce's disease (PD) is a destructive bacterial disease of grapes caused by Xylella fastidiosa which is xylem-confined. The tolerance level to this disease varies among Vitis species. Our research was aimed at identifying unique xylem sap proteins present in PD-tolerant Vitis species. The results showed wide variation in the xylem sap protein composition, where a set of polypeptides with pI between 4.5 and 4.7 and M(r) of 31 kDa were present in abundant amount in muscadine (Vitis rotundifolia, PD-tolerant), in reduced levels in Florida hybrid bunch (Vitis spp., PD-tolerant) and absent in bunch grapes (Vitis vinifera, PD-susceptible). Liquid chromatography/mass spectrometry/mass spectrometry analysis of these proteins revealed their similarity to beta-1, 3-glucanase, peroxidase, and a subunit of oxygen-evolving enhancer protein 1, which are known to play role in defense and oxygen generation. In addition, the amount of free amino acids and soluble sugars was found to be significantly lower in xylem sap of muscadine genotypes compared to V. vinifera genotypes, indicating that the higher nutritional value of bunch grape sap may be more suitable for Xylella growth. These data suggest that the presence of these unique proteins in xylem sap is vital for PD tolerance in muscadine and Florida hybrid bunch grapes.

  20. Rhizobium Strain Effects on Yield and Bleeding Sap Amino Compounds in Pisum sativum

    DEFF Research Database (Denmark)

    Rosendahl, Lis

    1984-01-01

    Bleeding sap composition, dry matter production and N distribution in pea (P. sativum L. cv. Bodil) grown with and without nitrate and nodulated with either R. leguminosarum strain 128c53 or strain 1044 were compared. Nitrate increased the total dry matter production of both symbioses, but decrea......Bleeding sap composition, dry matter production and N distribution in pea (P. sativum L. cv. Bodil) grown with and without nitrate and nodulated with either R. leguminosarum strain 128c53 or strain 1044 were compared. Nitrate increased the total dry matter production of both symbioses...... relative to the total N-accumulation was greater with strain 128c53 due to a higher production of nodule tissue. The root bleeding sap of the symbiosis with the greater yield (strain 1044) contained high levels of asparagine and aspartic acid. In the 128c53 symbiosis, glutamine plus homoserine accounted...... for a higher percentage of the organic solutes transporting newly assimilated N from the root system than in the association with 1044. The Rhizobium strain effect on amino compound composition of the bleeding sap may indicate an influence of the bacteroids on either the N-assimilatory enzyme system...

  1. Surface tension phenomena in the xylem sap of three diffuse porous temperate tree species

    Science.gov (United States)

    K. K. Christensen-Dalsgaard; M. T. Tyree; P. G. Mussone

    2011-01-01

    In plant physiology models involving bubble nucleation, expansion or elimination, it is typically assumed that the surface tension of xylem sap is equal to that of pure water, though this has never been tested. In this study we collected xylem sap from branches of the tree species Populus tremuloides, Betula papyrifera and Sorbus...

  2. Use of the heat dissipation method for sap flow measurement in citrus nursery trees1

    Directory of Open Access Journals (Sweden)

    Eduardo Augusto Girardi

    2010-12-01

    Full Text Available Sap flow could be used as physiological parameter to assist irrigation of screen house citrus nursery trees by continuous water consumption estimation. Herein we report a first set of results indicating the potential use of the heat dissipation method for sap flow measurement in containerized citrus nursery trees. 'Valencia' sweet orange [Citrus sinensis (L. Osbeck] budded on 'Rangpur' lime (Citrus limonia Osbeck was evaluated for 30 days during summer. Heat dissipation probes and thermocouple sensors were constructed with low-cost and easily available materials in order to improve accessibility of the method. Sap flow showed high correlation to air temperature inside the screen house. However, errors due to natural thermal gradient and plant tissue injuries affected measurement precision. Transpiration estimated by sap flow measurement was four times higher than gravimetric measurement. Improved micro-probes, adequate method calibration, and non-toxic insulating materials should be further investigated.

  3. Sap-feeding insects on forest trees along latitudinal gradients in northern Europe: a climate-driven patterns.

    Science.gov (United States)

    Kozlov, Mikhail V; Stekolshchikov, Andrey V; Söderman, Guy; Labina, Eugenia S; Zverev, Vitali; Zvereva, Elena L

    2015-01-01

    Knowledge of the latitudinal patterns in biotic interactions, and especially in herbivory, is crucial for understanding the mechanisms that govern ecosystem functioning and for predicting their responses to climate change. We used sap-feeding insects as a model group to test the hypotheses that the strength of plant-herbivore interactions in boreal forests decreases with latitude and that this latitudinal pattern is driven primarily by midsummer temperatures. We used a replicated sampling design and quantitatively collected and identified all sap-feeding insects from four species of forest trees along five latitudinal gradients (750-1300 km in length, ten sites in each gradient) in northern Europe (59 to 70°N and 10 to 60°E) during 2008-2011. Similar decreases in diversity of sap-feeding insects with latitude were observed in all gradients during all study years. The sap-feeder load (i.e. insect biomass per unit of foliar biomass) decreased with latitude in typical summers, but increased in an exceptionally hot summer and was independent of latitude during a warm summer. Analysis of combined data from all sites and years revealed dome-shaped relationships between the loads of sap-feeders and midsummer temperatures, peaking at 17 °C in Picea abies, at 19.5 °C in Pinus sylvestris and Betula pubescens and at 22 °C in B. pendula. From these relationships, we predict that the losses of forest trees to sap-feeders will increase by 0-45% of the current level in southern boreal forests and by 65-210% in subarctic forests with a 1 °C increase in summer temperatures. The observed relationships between temperatures and the loads of sap-feeders differ between the coniferous and deciduous tree species. We conclude that climate warming will not only increase plant losses to sap-feeding insects, especially in subarctic forests, but can also alter plant-plant interactions, thereby affecting both the productivity and the structure of future forest ecosystems. © 2014

  4. Beneficial effects of Acer okamotoanum sap on L-NAME-induced hypertension-like symptoms in a rat model.

    Science.gov (United States)

    Yang, Hyun; Hwang, Inho; Koo, Tae-Hyoung; Ahn, Hyo-Jin; Kim, Sun; Park, Mi-Jin; Choi, Won-Sil; Kang, Ha-Young; Choi, In-Gyu; Choi, Kyung-Chul; Jeung, Eui-Bae

    2012-02-01

    The sap of Acer okamotoanum has been termed 'bone-benefit-water' in Korea owing to its mineral and sugar content. In particular, the calcium (Ca) and potassium (K) concentrations of the sap of Acer okamotoanum are 40- and 20-times higher, respectively, than commercial spring water. In the present study, we examined whether Acer okamotoanum sap improves or prevents hypertension-like symptoms in a rat model. Male Sprague-Dawley rats (8-weeks-old) were provided commercial spring water supplemented with 25, 50 or 100% Acer okamotoanum sap, 3% potassium ions (K+) or captopril, and treated daily for 2 weeks with NG-nitro-L-arginine methyl ester (L-NAME; 100 mg/kg/day) by subcutaneous injection, in order to induce hypertensive symptoms. Rats were euthanized 6 h following the final injection. To assess the effect of the sap on hypertension-like symptoms, we examined the mean blood pressure (BP), protein levels and localization of endothelial nitric oxide synthase (eNOS) in the descending aorta of the rats. BP levels were significantly lower in hypertensive rats received 25, 50 and 100% sap compared with rats who were administered only commercial spring water. Protein levels of eNOS were repressed in L-NAME-only-treated rats, but were elevated in the descending aorta of rats administered captopril, K+ water and Acer okamotoanum sap (25, 50 and 100%) up to the level of the sham group provided commercial spring water, and then injected with dimethyl sulfoxide for the same period of time. Localized eNOS protein was abundantly expressed in the perivascular descending aorta adipose tissue of the rats. Taken together, these results demonstrated that the sap of Acer okamotoanum ameliorated high BP induced by L-NAME treatment in a rat model.

  5. Determining Accuracy of Thermal Dissipation Methods-based Sap Flux in Japanese Cedar Trees

    Science.gov (United States)

    Su, Man-Ping; Shinohara, Yoshinori; Laplace, Sophie; Lin, Song-Jin; Kume, Tomonori

    2017-04-01

    Thermal dissipation method, one kind of sap flux measurement method that can estimate individual tree transpiration, have been widely used because of its low cost and uncomplicated operation. Although thermal dissipation method is widespread, the accuracy of this method is doubted recently because some tree species materials in previous studies were not suitable for its empirical formula from Granier due to difference of wood characteristics. In Taiwan, Cryptomeria japonica (Japanese cedar) is one of the dominant species in mountainous area, quantifying the transpiration of Japanese cedar trees is indispensable to understand water cycling there. However, no one have tested the accuracy of thermal dissipation methods-based sap flux for Japanese cedar trees in Taiwan. Thus, in this study we conducted calibration experiment using twelve Japanese cedar stem segments from six trees to investigate the accuracy of thermal dissipation methods-based sap flux in Japanese cedar trees in Taiwan. By pumping water from segment bottom to top and inserting probes into segments to collect data simultaneously, we compared sap flux densities calculated from real water uptakes (Fd_actual) and empirical formula (Fd_Granier). Exact sapwood area and sapwood depth of each sample were obtained from dying segment with safranin stain solution. Our results showed that Fd_Granier underestimated 39 % of Fd_actual across sap flux densities ranging from 10 to 150 (cm3m-2s-1); while applying sapwood depth corrected formula from Clearwater, Fd_Granier became accurately that only underestimated 0.01 % of Fd_actual. However, when sap flux densities ranging from 10 to 50 (cm3m-2s-1)which is similar with the field data of Japanese cedar trees in a mountainous area of Taiwan, Fd_Granier underestimated 51 % of Fd_actual, and underestimated 26 % with applying Clearwater sapwood depth corrected formula. These results suggested sapwood depth significantly impacted on the accuracy of thermal dissipation

  6. Determining sap sweetness in small sugar maple trees

    Science.gov (United States)

    Melvin R. Koelling

    1967-01-01

    Describes a technique based on the use of a hypodermic needle for determining sap-sugar concentrations in small trees. The technique is applicable to pot cultures in greenhouses and also, with the use of a movable shelter, to seedlings in nursery beds.

  7. Ray tissues as an indirect measure of relative sap-sugar concentration in sugar maple

    Science.gov (United States)

    Peter W. Garrett; Kenneth R. Dudzik; Kenneth R. Dudzik

    1989-01-01

    Attempts to correlate ray tissue as a percentage of total wood volume with sap-sugar concentrations of sugar maple progenies were unsuccessful. These results raise doubts about our ability to use a relatively constant value such as ray-tissue volume in a selection program designed to increase the sap-sugar concentration of sugar maple seedlings.

  8. Predictive value of SAPS II and APACHE II scoring systems for patient outcome in a medical intensive care unit

    Directory of Open Access Journals (Sweden)

    Amina Godinjak

    2016-11-01

    Full Text Available Objective. The aim is to determine SAPS II and APACHE II scores in medical intensive care unit (MICU patients, to compare them for prediction of patient outcome, and to compare with actual hospital mortality rates for different subgroups of patients. Methods. One hundred and seventy-four patients were included in this analysis over a oneyear period in the MICU, Clinical Center, University of Sarajevo. The following patient data were obtained: demographics, admission diagnosis, SAPS II, APACHE II scores and final outcome. Results. Out of 174 patients, 70 patients (40.2% died. Mean SAPS II and APACHE II scores in all patients were 48.4±17.0 and 21.6±10.3 respectively, and they were significantly different between survivors and non-survivors. SAPS II >50.5 and APACHE II >27.5 can predict the risk of mortality in these patients. There was no statistically significant difference in the clinical values of SAPS II vs APACHE II (p=0.501. A statistically significant positive correlation was established between the values of SAPS II and APACHE II (r=0.708; p=0.001. Patients with an admission diagnosis of sepsis/septic shock had the highest values of both SAPS II and APACHE II scores, and also the highest hospital mortality rate of 55.1%. Conclusion. Both APACHE II and SAPS II had an excellent ability to discriminate between survivors and non-survivors. There was no significant difference in the clinical values of SAPS II and APACHE II. A positive correlation was established between them. Sepsis/septic shock patients had the highest predicted and observed hospital mortality rate.

  9. Sap flux density and stomatal conductance of European beech and common oak trees in pure and mixed stands during the summer drought of 2003

    Science.gov (United States)

    Jonard, F.; André, F.; Ponette, Q.; Vincke, C.; Jonard, M.

    2011-10-01

    SummarySap flux density of European beech and common oak trees was determined from sap flow measurements in pure and mixed stands during the summer drought of 2003. Eight trees per species and per stand were equipped with sap flow sensors. Soil water content was monitored in each stand at different depths by using time-domain reflectometry (TDR). Leaf area index and vertical root distribution were also investigated during the growing season. From sap flux density ( SFD) data, mean stomatal conductance of individual trees ( G s) was calculated by inverting the Penman-Monteith equation. Linear mixed models were developed to analyse the effects of species and stand type (pure vs. mixed) on SFD and G s and on their sensitivity to environmental variables (vapour pressure deficit ( D), incoming solar radiation ( R G), and relative extractable water ( REW)). For reference environmental conditions, we did not find any tree species or stand type effects on SFD. The sensitivity of SFD to D was higher for oak than for beech in the pure stands ( P sapwood-to-leaf area ratio compared to oak. The sensitivity of G s to REW was higher for beech than for oak and was ascribed to a higher vulnerability of beech to air embolism and to a more sensitive stomatal regulation. The sensitivity of beech G s to REW was lower in the mixed than in the pure stand, which could be explained by a better sharing of the resources in the mixture, by facilitation processes (hydraulic lift), and by a rainfall partitioning in favour of beech.

  10. USE OF ELECTRONIC EDUCATIONAL RESOURCES WHEN TRAINING IN WORK WITH SPREADSHEETS

    Directory of Open Access Journals (Sweden)

    Х А Гербеков

    2017-12-01

    Full Text Available Today the tools for maintaining training courses based on opportunities of information and communication technologies are developed. Practically in all directions of preparation and on all subject matters electronic textbook and self-instruction manuals are created. Nevertheless the industry of computer educational and methodical materials actively develops and gets more and more areas of development and introduction. In this regard more and more urgent is a problem of development of the electronic educational resources adequate to modern educational requirements. Creation and the organization of training courses with use of electronic educational resources in particular on the basis of Internet technologies remains a difficult methodical task.In article the questions connected with development of electronic educational resources for use when studying the substantial line “Information technologies” of a school course of informatics in particular for studying of spreadsheets are considered. Also the analysis of maintenance of a school course and the unified state examination from the point of view of representation of task in him corresponding to the substantial line of studying “Information technologies” on mastering technology of information processing in spreadsheets and the methods of visualization given by means of charts and schedules is carried out.

  11. Hydrographic survey of Chaktomuk, the confluence of the Mekong, Tonlé Sap, and Bassac Rivers near Phnom Penh, Cambodia, 2012

    Science.gov (United States)

    Dietsch, Benjamin J.; Densmore, Brenda K.; Wilson, Richard C.

    2014-01-01

    The U.S. Geological Survey, in cooperation with the U.S. Department of State, Mekong River Commission, Phnom Penh Autonomous Port, and the Cambodian Ministry of Water Resources and Meteorology, completed a hydrographic survey of Chaktomuk, which is the confluence of the Mekong, Tonlé Sap (also spelled Tônlé Sab), and Bassac Rivers near Phnom Penh, Cambodia. The hydrographic survey used a high-resolution multibeam echosounder mapping system to map the riverbed during April 21–May 2, 2012.

  12. DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice.

    Science.gov (United States)

    Cox, Nehemiah; Pilling, Darrell; Gomer, Richard H

    2015-07-07

    Fibrosis is caused by scar tissue formation in internal organs and is associated with 45% of deaths in the United States. Two closely related human serum proteins, serum amyloid P (SAP) and C-reactive protein (CRP), strongly affect fibrosis. In multiple animal models, and in Phase 1 and Phase 2 clinical trials, SAP affects several aspects of the innate immune system to reduce fibrosis, whereas CRP appears to potentiate fibrosis. However, SAP and CRP bind the same Fcγ receptors (FcγR) with similar affinities, and why SAP and CRP have opposing effects is unknown. Here, we report that SAP but not CRP binds the receptor DC-SIGN (SIGN-R1) to affect the innate immune system, and that FcγR are not necessary for SAP function. A polycyclic aminothiazole DC-SIGN ligand and anti-DC-SIGN antibodies mimic SAP effects in vitro. In mice, the aminothiazole reduces neutrophil accumulation in a model of acute lung inflammation and, at 0.001 mg/kg, alleviates pulmonary fibrosis by increasing levels of the immunosuppressant IL-10. DC-SIGN (SIGN-R1) is present on mouse lung epithelial cells, and SAP and the aminothiazole potentiate IL-10 production from these cells. Our data suggest that SAP activates DC-SIGN to regulate the innate immune system differently from CRP, and that DC-SIGN is a target for antifibrotics.

  13. The adaptor protein SAP regulates type II NKT-cell development, cytokine production, and cytotoxicity against lymphoma.

    Science.gov (United States)

    Weng, Xiufang; Liao, Chia-Min; Bagchi, Sreya; Cardell, Susanna L; Stein, Paul L; Wang, Chyung-Ru

    2014-12-01

    CD1d-restricted NKT cells represent a unique lineage of immunoregulatory T cells that are divided into two groups, type I and type II, based on their TCR usage. Because there are no specific tools to identify type II NKT cells, little is known about their developmental requirements and functional regulation. In our previous study, we showed that signaling lymphocytic activation molecule associated protein (SAP) is essential for the development of type II NKT cells. Here, using a type II NKT-cell TCR transgenic mouse model, we demonstrated that CD1d-expressing hematopoietic cells, but not thymic epithelial cells, meditate efficient selection of type II NKT cells. Furthermore, we showed that SAP regulates type II NKT-cell development by controlling early growth response 2 protein and promyelocytic leukemia zinc finger expression. SAP-deficient 24αβ transgenic T cells (24αβ T cells) exhibited an immature phenotype with reduced Th2 cytokine-producing capacity and diminished cytotoxicity to CD1d-expressing lymphoma cells. The impaired IL-4 production by SAP-deficient 24αβ T cells was associated with reduced IFN regulatory factor 4 and GATA-3 induction following TCR stimulation. Collectively, these data suggest that SAP is critical for regulating type II NKT cell responses. Aberrant responses of these T cells may contribute to the immune dysregulation observed in X-linked lymphoproliferative disease caused by mutations in SAP. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Phloem-sap-dynamics sensor device for monitoring photosynthates transportation in plant shoots

    Science.gov (United States)

    Yano, Yuya; Ono, Akihito; Terao, Kyohei; Suzuki, Takaaki; Takao, Hidekuni; Kobayashi, Tsuyoshi; Kataoka, Ikuo; Shimokawa, Fusao

    2018-06-01

    We propose a microscale phloem-sap-dynamics sensor device to obtain the index of an internal plant condition regarding the transportation of primary photosynthates in phloem, which is an essential indicator of stable crop production under controlled-growth environments. In detail, we integrated a conventional Granier sensor with a thermal-flow sensor and devised an improved sensor device to quantify such index, including the information on velocity and direction of the phloem-sap flow using the microelectromechanical systems (MEMS) technology. The experimental results showed that although the proposed sensor device was approximately only 1/10 the size of the conventional Granier sensor, it could generate an output nearly equal to that of the conventional sensor. Furthermore, experiments using mimicked plants demonstrated that the proposed device could measure minute flow velocities in the range of 0–200 µm/s, which are generally known as the phloem-sap flow velocity, and simultaneously detect the flow direction.

  15. 49 CFR 40.309 - What are the employer's responsibilities with respect to the SAP's directions for follow-up tests?

    Science.gov (United States)

    2010-10-01

    ... respect to the SAP's directions for follow-up tests? 40.309 Section 40.309 Transportation Office of the... responsibilities with respect to the SAP's directions for follow-up tests? (a) As the employer, you must carry out the SAP's follow-up testing requirements. You may not allow the employee to continue to perform safety...

  16. 49 CFR 40.287 - What information is an employer required to provide concerning SAP services to an employee who...

    Science.gov (United States)

    2010-10-01

    ... provide concerning SAP services to an employee who has a DOT drug and alcohol regulation violation? 40.287... § 40.287 What information is an employer required to provide concerning SAP services to an employee who... (including an applicant or new employee) who violates a DOT drug and alcohol regulation a listing of SAPs...

  17. Inhibitory effects of soluble algae products (SAP) released by Scenedesmus sp. LX1 on its growth and lipid production.

    Science.gov (United States)

    Zhang, Tian-Yuan; Yu, Yin; Wu, Yin-Hu; Hu, Hong-Ying

    2013-10-01

    Soluble algal products (SAP) accumulated in culture medium via water reuse may affect the growth of microalga during the cultivation. Scenedesmus sp. LX1, a freshwater microalga, was used in this study to investigate the effect of SAP on growth and lipid production of microalga. Under the SAP concentrations of 6.4-25.8 mg L(-1), maximum algal density (K) and maximum growth rate (Rmax) of Scenedesmus sp. LX1 were decreased by 50-80% and 35-70% compared with the control group, respectively. The effect of SAP on lipid accumulation of Scenedesmus sp. LX1 was non-significant. According to hydrophilic-hydrophobic and acid-base properties, SAP was fractionized into six fractions. All of the fractions could inhibit the growth of Scenedesmus sp. LX1. Organic bases (HIB, HOB) and hydrophilic acids (HIA) showed the strongest inhibition. HIA could also decrease the lipid content of Scenedesmus sp. LX1 by 59.2%. As the inhibitory effect, SAP should be seriously treated before water reuse. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Radial variation in sap velocity as a function of stem diameter and sapwood thickness in yellow-poplar trees.

    Science.gov (United States)

    Wullschleger, Stan D.; King, Anthony W.

    2000-04-01

    Canopy transpiration and forest water use are frequently estimated as the product of sap velocity and cross-sectional sapwood area. Few studies, however, have considered whether radial variation in sap velocity and the proportion of sapwood active in water transport are significant sources of uncertainty in the extrapolation process. Therefore, radial profiles of sap velocity were examined as a function of stem diameter and sapwood thickness for yellow-poplar (Liriodendron tulipifera L.) trees growing on two adjacent watersheds in eastern Tennessee. The compensation heat pulse velocity technique was used to quantify sap velocity at four equal-area depths in 20 trees that ranged in stem diameter from 15 to 69 cm, and in sapwood thickness from 2.1 to 14.8 cm. Sap velocity was highly dependent on the depth of probe insertion into the sapwood. Rates of sap velocity were greatest for probes located in the two outer sapwood annuli (P1 and P2) and lowest for probes in closest proximity to the heartwood (P3 and P4). Relative sap velocities averaged 0.98 at P1, 0.66 at P2, 0.41 at P3 and 0.35 at P4. Tree-specific sap velocities measured at each of the four probe positions, divided by the maximum sap velocity measured (usually at P1 or P2), indicated that the fraction of sapwood functional in water transport (f(S)) varied between 0.49 and 0.96. There was no relationship between f(S) and sapwood thickness, or between f(S) and stem diameter. The fraction of functional sapwood averaged 0.66 +/- 0.13 for trees on which radial profiles were determined. No significant depth-related differences were observed for sapwood density, which averaged 469 kg m(-3) across all four probe positions. There was, however, a significant decline in sapwood water content between the two outer probe positions (1.04 versus 0.89 kg kg(-1)). This difference was not sufficient to account for the observed radial variation in sap velocity. A Monte-Carlo analysis indicated that the standard error in

  19. Baseliner: an open source, interactive tool for processing sap flux data from thermal dissipation probes.

    Science.gov (United States)

    Andrew C. Oishi; David Hawthorne; Ram Oren

    2016-01-01

    Estimating transpiration from woody plants using thermal dissipation sap flux sensors requires careful data processing. Currently, researchers accomplish this using spreadsheets, or by personally writing scripts for statistical software programs (e.g., R, SAS). We developed the Baseliner software to help establish a standardized protocol for processing sap...

  20. Protein tyrosine phosphatase SAP-1 protects against colitis through regulation of CEACAM20 in the intestinal epithelium.

    Science.gov (United States)

    Murata, Yoji; Kotani, Takenori; Supriatna, Yana; Kitamura, Yasuaki; Imada, Shinya; Kawahara, Kohichi; Nishio, Miki; Daniwijaya, Edwin Widyanto; Sadakata, Hisanobu; Kusakari, Shinya; Mori, Munemasa; Kanazawa, Yoshitake; Saito, Yasuyuki; Okawa, Katsuya; Takeda-Morishita, Mariko; Okazawa, Hideki; Ohnishi, Hiroshi; Azuma, Takeshi; Suzuki, Akira; Matozaki, Takashi

    2015-08-04

    Intestinal epithelial cells contribute to regulation of intestinal immunity in mammals, but the detailed molecular mechanisms of such regulation have remained largely unknown. Stomach-cancer-associated protein tyrosine phosphatase 1 (SAP-1, also known as PTPRH) is a receptor-type protein tyrosine phosphatase that is localized specifically at microvilli of the brush border in gastrointestinal epithelial cells. Here we show that SAP-1 ablation in interleukin (IL)-10-deficient mice, a model of inflammatory bowel disease, resulted in a marked increase in the severity of colitis in association with up-regulation of mRNAs for various cytokines and chemokines in the colon. Tyrosine phosphorylation of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 20, an intestinal microvillus-specific transmembrane protein of the Ig superfamily, was greatly increased in the intestinal epithelium of the SAP-1-deficient animals, suggesting that this protein is a substrate for SAP-1. Tyrosine phosphorylation of CEACAM20 by the protein tyrosine kinase c-Src and the consequent association of CEACAM20 with spleen tyrosine kinase (Syk) promoted the production of IL-8 in cultured cells through the activation of nuclear factor-κB (NF-κB). In addition, SAP-1 and CEACAM20 were found to form a complex through interaction of their ectodomains. SAP-1 and CEACAM20 thus constitute a regulatory system through which the intestinal epithelium contributes to intestinal immunity.

  1. Dragon's Blood Sap (Croton Lechleri) As Storage Medium For Avulsed Teeth: In Vitro Study Of Cell Viability.

    Science.gov (United States)

    Martins, Christine Men; Hamanaka, Elizane Ferreira; Hoshida, Thayse Yumi; Sell, Ana Maria; Hidalgo, Mirian Marubayashi; Silveira, Catarina Soares; Poi, Wilson Roberto

    2016-01-01

    Tooth replantation success depends on the condition of cementum periodontal ligament after tooth avulsion; which is influenced by storage medium. The dragon's blood (Croton lechleri) sap has been suggested as a promising medium because it supports collagen formation and exhibits healing, anti-inflammatory and antimicrobial properties. Thus, the aim of this study was to evaluate the efficacy of dragon's blood sap as a storage medium for avulsed teeth through evaluation of functional and metabolic cell viability. This in vitro study compared the efficacy of different storage media to maintain the viability of human peripheral blood mononuclear and periodontal ligament cells. A 10% dragon's blood sap was tested while PBS was selected as its control. Ultra pasteurized whole milk was used for comparison as a commonly used storage medium. DMEM and distilled water were the positive and negative controls, respectively. The viability was assessed through trypan blue exclusion test and colorimetric MTT assay after 1, 3, 6, 10 and 24 h of incubation. The dragon's blood sap showed promising results due to its considerable maintenance of cell viability. For trypan blue test, the dragon's blood sap was similar to milk (psap showed better results than all storage media, even better than milk (psap was as effective as milk, the gold standard for storage medium. The experimental sap preserved the membrane of all cells and the functional viability of periodontal ligament cells.

  2. The Adaptor Protein SAP Regulates Type II NKT Cell Development, Cytokine Production and Cytotoxicity Against Lymphoma1

    Science.gov (United States)

    Weng, Xiufang; Liao, Chia-Min; Bagchi, Sreya; Cardell, Susanna L.; Stein, Paul L.; Wang, Chyung-Ru

    2014-01-01

    CD1d-restricted NKT cells represent a unique lineage of immunoregulatory T cells that are divided into two groups, type I and type II, based on their TCR usage. Because there are no specific tools to identify type II NKT cells, little is known about their developmental requirements and functional regulation. In our previous study, we showed that signaling lymphocytic activation molecule-associated protein (SAP) is essential for the development of type II NKT cells. Here, using a type II NKT cell TCR transgenic mouse model (24αβTg), we demonstrated that CD1d-expressing hematopoietic cells but not thymic epithelial cells meditate efficient selection of type II NKT cells. Further, we showed that SAP regulates type II NKT cell development by controlling Egr2 and PLZF expression. SAP-deficient 24αβ transgenic T cells (24αβ T cells) exhibited an immature phenotype with reduced Th2 cytokine-producing capacity and diminished cytotoxicity to CD1d-expressing lymphoma cells. The impaired IL-4 production by SAP-deficient 24αβ T cells was associated with reduced IRF4 and GATA-3 induction following TCR stimulation. Collectively, these data suggest that SAP is critical for regulating type II NKT cell responses. Aberrant responses of these T cells may contribute to the immune dysregulation observed in X-linked lymphoproliferative disease caused by mutations in SAP. PMID:25236978

  3. Variability in radial sap flux density patterns and sapwood area among seven co-occurring temperate broad-leaved tree species.

    Science.gov (United States)

    Gebauer, Tobias; Horna, Viviana; Leuschner, Christoph

    2008-12-01

    Forest transpiration estimates are frequently based on xylem sap flux measurements in the outer sections of the hydro-active stem sapwood. We used Granier's constant-heating technique with heating probes at various xylem depths to analyze radial patterns of sap flux density in the sapwood of seven broad-leaved tree species differing in wood density and xylem structure. Study aims were to (1) compare radial sap flux density profiles between diffuse- and ring-porous trees and (2) analyze the relationship between hydro-active sapwood area and stem diameter. In all investigated species except the diffuse-porous beech (Fagus sylvatica L.) and ring-porous ash (Fraxinus excelsior L.), sap flux density peaked at a depth of 1 to 4 cm beneath the cambium, revealing a hump-shaped curve with species-specific slopes. Beech and ash reached maximum sap flux densities immediately beneath the cambium in the youngest annual growth rings. Experiments with dyes showed that the hydro-active sapwood occupied 70 to 90% of the stem cross-sectional area in mature trees of diffuse-porous species, whereas it occupied only about 21% in ring-porous ash. Dendrochronological analyses indicated that vessels in the older sapwood may remain functional for 100 years or more in diffuse-porous species and for up to 27 years in ring-porous ash. We conclude that radial sap flux density patterns are largely dependent on tree species, which may introduce serious bias in sap-flux-derived forest transpiration estimates, if non-specific sap flux profiles are assumed.

  4. Water-Energy-Food Nexus in a Transboundary River Basin: The Case of Tonle Sap Lake, Mekong River Basin

    Directory of Open Access Journals (Sweden)

    Marko Keskinen

    2015-10-01

    Full Text Available The water-energy-food nexus is promoted as a new approach for research and policy-making. But what does the nexus mean in practice and what kinds of benefits does it bring? In this article we share our experiences with using a nexus approach in Cambodia’s Tonle Sap Lake area. We conclude that water, energy and food security are very closely linked, both in the Tonle Sap and in the transboundary Mekong River Basin generally. The current drive for large-scale hydropower threatens water and food security at both local and national scales. Hence, the nexus provides a relevant starting point for promoting sustainable development in the Mekong. We also identify and discuss two parallel dimensions for the nexus, with one focusing on research and analysis and the other on integrated planning and cross-sectoral collaboration. In our study, the nexus approach was particularly useful in facilitating collaboration and stakeholder engagement. This was because the nexus approach clearly defines the main themes included in the process, and at the same time widens the discussion from mere water resource management into the broader aspects of water, energy and food security.

  5. The Adaptor Protein SAP Directly Associates with CD3ζ Chain and Regulates T Cell Receptor Signaling

    Science.gov (United States)

    Proust, Richard; Bertoglio, Jacques; Gesbert, Franck

    2012-01-01

    Mutations altering the gene encoding the SLAM associated protein (SAP) are responsible for the X-linked lymphoproliferative disease or XLP1. Its absence is correlated with a defective NKT cells development, a decrease in B cell functions and a reduced T cells and NK cells cytotoxic activities, thus leading to an immunodeficiency syndrome. SAP is a small 128 amino-acid long protein that is almost exclusively composed of an SH2 domain. It has been shown to interact with the CD150/SLAM family of receptors, and in a non-canonical manner with SH3 containing proteins such as Fyn, βPIX, PKCθ and Nck1. It would thus play the role of a minimal adaptor protein. It has been shown that SAP plays an important function in the activation of T cells through its interaction with the SLAM family of receptors. Therefore SAP defective T cells display a reduced activation of signaling events downstream of the TCR-CD3 complex triggering. In the present work, we evidence that SAP is a direct interactor of the CD3ζ chain. This direct interaction occurs through the first ITAM of CD3ζ, proximal to the membrane. Additionally, we show that, in the context of the TCR-CD3 signaling, an Sh-RNA mediated silencing of SAP is responsible for a decrease of several canonical T cell signaling pathways including Erk, Akt and PLCγ1 and to a reduced induction of IL-2 and IL-4 mRNA. Altogether, we show that SAP plays a central function in the T cell activation processes through a direct association with the CD3 complex. PMID:22912825

  6. Analysis of plastic residues in maple sap and syrup collected from tubing systems sanitized with isopropyl alcohol

    Directory of Open Access Journals (Sweden)

    Luc Lagacé

    2017-05-01

    Full Text Available A plastic tubing system operated under vacuum is usually used to collect sap from maple trees during spring time to produce maple syrup. This system is commonly sanitized with isopropyl alcohol (IPA to remove microbial contamination colonizing the system during the sugar season. Questions have been raised whether IPA would contribute to the leaching of plastic residues in maple sap and syrup coming from sanitized systems. First, an extraction experiment was performed in the lab on commercial plastic tubing materials that were submitted to IPA under harsh conditions. The results of the GC-MS analysis revealed the presence of many compounds that served has target for further tests. Secondly, tests were done on early and mid-season maple sap and syrup coming from many sugarbushes using IPA or not to determine potential concentrations of plastic residues. Results obtained from sap and syrup samples showed that no quantifiable (< 1–75 μg/L concentration of any plastic molecules tested was determined in all samples coming from IPA treated or not treated systems. However, some samples of first sap run used as a rinse solution to be discarded before the season start and that were coming from non sanitized or IPA sanitized systems, showed quantifiable concentrations of chemical residue such as ultraviolet protector (octabenzone. These results show that IPA can be safely used to sanitize maple sap collection system in regards to the leaching of plastic residues in maple sap and syrup and reinforced the need to thoroughly rinse the tubing system at the beginning of the season for both sanitized and non sanitized systems. Keywords: Food science, Food safety, Materials chemistry

  7. Analytical Study of Usage of Electronic Information Resources at Pharmacopoeial Libraries in India

    Directory of Open Access Journals (Sweden)

    Sunil Tyagi

    2014-02-01

    Full Text Available The objective of this study is to know the rate and purpose of the use of e-resource by the scientists at pharmacopoeial libraries in India. Among other things, this study examined the preferences of the scientists toward printed books and journals, electronic information resources, and pattern of using e-resources. Non-probability sampling specially accidental and purposive technique was applied in the collection of primary data through administration of user questionnaire. The sample respondents chosen for the study consists of principle scientific officer, senior scientific officer, scientific officer, and scientific assistant of different division of the laboratories, namely, research and development, pharmaceutical chemistry, pharmacovigilance, pharmacology, pharmacogonosy, and microbiology. The findings of the study reveal the personal experiences and perceptions they have had on practice and research activity using e-resource. The major findings indicate that of the total anticipated participants, 78% indicated that they perceived the ability to use computer for electronic information resources. The data analysis shows that all the scientists belonging to the pharmacopoeial libraries used electronic information resources to address issues relating to drug indexes and compendia, monographs, drugs obtained through online databases, e-journals, and the Internet sources—especially polices by regulatory agencies, contacts, drug promotional literature, and standards.

  8. The adaptor protein SAP directly associates with PECAM-1 and regulates PECAM-1-mediated-cell adhesion in T-like cell lines.

    Science.gov (United States)

    Proust, Richard; Crouin, Catherine; Gandji, Leslie Yewakon; Bertoglio, Jacques; Gesbert, Franck

    2014-04-01

    SAP is a small cytosolic adaptor protein expressed in hematopoietic lineages whose main function is to regulate intracellular signaling pathways induced by the triggering of members of the SLAM receptor family. In this paper, we have identified the adhesion molecule PECAM-1 as a new partner for SAP in a conditional yeast two-hybrid screen. PECAM-1 is an immunoglobulin-like molecule expressed by endothelial cells and leukocytes, which possesses both pro- and anti-inflammatory properties. However, little is known about PECAM-1 functions in T cells. We show that SAP directly and specifically interacts with the cytosolic tyrosine 686 of PECAM-1. We generated different T-like cell lines in which SAP or PECAM-1 are expressed or down modulated and we demonstrate that a diminished SAP expression correlates with a diminished PECAM-1-mediated adhesion. Although SAP has mainly been shown to associate with SLAM receptors, we evidence here that SAP is a new actor downstream of PECAM-1. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Preliminary results of sugar maple carbohydrate and growth response under vacuum and gravity sap extraction

    Science.gov (United States)

    Mark L. Isselhardt; Timothy D. Perkins; Abby K. van den Berg; Paul G. Schaberg

    2016-01-01

    Recent technological advancements have increased the amount of sugar-enriched sap that can be extracted from sugar maple (Acer saccharum). This pilot study quantified overall sugar removal and the impacts of vacuum (60 cm Hg) and gravity sap extraction on residual nonstructural carbohydrate (NSC) concentrations and on stem and twig growth. Vacuum...

  10. Page 170 Use of Electronic Resources by Undergraduates in Two ...

    African Journals Online (AJOL)

    undergraduate students use electronic resources such as NUC virtual library, HINARI, ... web pages articles from magazines, encyclopedias, pamphlets and other .... of Nigerian university libraries have Internet connectivity, some of the system.

  11. [Sap flow characteristics of Quercus liaotungensis in response to sapwood area and soil moisture in the loess hilly region, China].

    Science.gov (United States)

    Lyu, Jin Lin; He, Qiu Yue; Yan, Mei Jie; Li, Guo Qing; Du, Sheng

    2018-03-01

    To examine the characteristics of sap flow in Quercus liaotungensis and their response to environmental factors under different soil moisture conditions, Granier-type thermal dissipation probes were used to measure xylem sap flow of trees with different sapwood area in a natural Q. liaotungensis forest in the loess hilly region. Solar radiation, air temperature, relative air humidity, precipitation, and soil moisture were monitored during the study period. The results showed that sap flux of Q. liaotungensis reached daily peaks earlier than solar radiation and vapor pressure deficit. The diurnal dynamics of sap flux showed a similar pattern to those of the environmental factors. Trees had larger sap flux during the period with higher soil moisture. Under the same soil moisture conditions, trees with larger diameter and sapwood areas had significantly higher sap flux than those with smaller diameter and sapwood areas. Sap flux could be fitted with vapor pressure deficit, solar radiation, and the integrated index of the two factors using exponential saturation function. Differences in the fitted curves and parameters suggested that sap flux tended to reach saturation faster under higher soil moisture. Furthermore, trees in the smaller diameter class were more sensitive to the changes of soil moisture. The ratio of daily sap flux per unit vapor pressure deficit under lower soil moisture condition to that under higher soil moisture condition was linearly correlated to sapwood area. The regressive slope in smaller diameter class was larger than that in bigger diameter class, which further indicated the higher sensitivity of trees with smaller diameter class to soil moisture. These results indicated that wider sapwood of larger diameter class provided a buffer against drought stress.

  12. Use of APACHE II and SAPS II to predict mortality for hemorrhagic and ischemic stroke patients.

    Science.gov (United States)

    Moon, Byeong Hoo; Park, Sang Kyu; Jang, Dong Kyu; Jang, Kyoung Sool; Kim, Jong Tae; Han, Yong Min

    2015-01-01

    We studied the applicability of the Acute Physiology and Chronic Health Evaluation II (APACHE II) and Simplified Acute Physiology Score II (SAPS II) in patients admitted to the intensive care unit (ICU) with acute stroke and compared the results with the Glasgow Coma Scale (GCS) and National Institutes of Health Stroke Scale (NIHSS). We also conducted a comparative study of accuracy for predicting hemorrhagic and ischemic stroke mortality. Between January 2011 and December 2012, ischemic or hemorrhagic stroke patients admitted to the ICU were included in the study. APACHE II and SAPS II-predicted mortalities were compared using a calibration curve, the Hosmer-Lemeshow goodness-of-fit test, and the receiver operating characteristic (ROC) curve, and the results were compared with the GCS and NIHSS. Overall 498 patients were included in this study. The observed mortality was 26.3%, whereas APACHE II and SAPS II-predicted mortalities were 35.12% and 35.34%, respectively. The mean GCS and NIHSS scores were 9.43 and 21.63, respectively. The calibration curve was close to the line of perfect prediction. The ROC curve showed a slightly better prediction of mortality for APACHE II in hemorrhagic stroke patients and SAPS II in ischemic stroke patients. The GCS and NIHSS were inferior in predicting mortality in both patient groups. Although both the APACHE II and SAPS II systems can be used to measure performance in the neurosurgical ICU setting, the accuracy of APACHE II in hemorrhagic stroke patients and SAPS II in ischemic stroke patients was superior. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Effect of preservation methods of oil palm sap (Elaeis guineensis) on the reproductive indices of male wistar rats.

    Science.gov (United States)

    Ikegwu, Theophilus Maduabuchukwu; Okafor, Gabriel Ifeanyi; Ochiogu, Izuchukwu Shedrack

    2014-12-01

    Thirty male Wistar rats, split into five groups of six rats each, were administered different forms of oil palm tree (Elaeis guineensis) sap samples by gavage based on 1.5% of their weekly body weights. Group 1 which served as control received only water, group 2 received pasteurized palm sap (PPS), group 3 received market palm wine (MPW), group 4 received frozen palm sap (FPS), whereas group 5 received fresh palm sap (FrPS). Chemical composition of the sap samples was determined. Normal feed and water were fed ad libitum. After 2 months of treatment, each male rat group was allowed 7 days to mate with six female Wistar rats. Thereafter, blood and epididymal samples were collected for testosterone assay and sperm count, respectively, before they were humanely sacrificed and testicular tissues taken for testicular histology. Litter weight and size of the pups produced by the females of each group were determined at birth. The sap samples contained carbohydrate (0.01-11.71%), protein (1.56-1.95%), ash (0.22-0.35%), moisture (92.55-98.24%), and alcohol (0.26-3.50%). PPS-treated rat group had significantly (Psap, impacted negatively on the reproductive indices of male animals.

  14. Human SAP is a novel peptidoglycan recognition protein that induces complement- independent phagocytosis of Staphylococcus aureus

    Science.gov (United States)

    An, Jang-Hyun; Kurokawa, Kenji; Jung, Dong-Jun; Kim, Min-Jung; Kim, Chan-Hee; Fujimoto, Yukari; Fukase, Koichi; Coggeshall, K. Mark; Lee, Bok Luel

    2014-01-01

    The human pathogen Staphylococcus aureus is responsible for many community-acquired and hospital-associated infections and is associated with high mortality. Concern over the emergence of multidrug-resistant strains has renewed interest in the elucidation of host mechanisms that defend against S. aureus infection. We recently demonstrated that human serum mannose-binding lectin (MBL) binds to S. aureus wall teichoic acid (WTA), a cell wall glycopolymer, a discovery that prompted further screening to identify additional serum proteins that recognize S. aureus cell wall components. In this report, we incubated human serum with 10 different S. aureus mutants and determined that serum amyloid P component (SAP) bound specifically to a WTA-deficient S. aureus ΔtagO mutant, but not to tagO-complemented, WTA-expressing cells. Biochemical characterization revealed that SAP recognizes bacterial peptidoglycan as a ligand and that WTA inhibits this interaction. Although SAP binding to peptidoglycan was not observed to induce complement activation, SAP-bound ΔtagO cells were phagocytosed by human polymorphonuclear leukocytes in an Fcγ receptor-dependent manner. These results indicate that SAP functions as a host defense factor, similar to other peptidoglycan recognition proteins and nucleotide-binding oligomerization domain (NOD)-like receptors. PMID:23966633

  15. SAID/SAPS Revisited: A Causal Relation to the Substorm Current Wedge

    Science.gov (United States)

    Mishin, E. V.

    2017-12-01

    We present multi-spacecraft observations of enhanced flow/electric field channels in the inner magnetosphere and conjugate subauroral ionosphere, i.e., subauroral polarization streams (SAPS) near dusk and subauroral ion drifts (SAID) near midnight. The channels collocate with ring current (RC) injections lagging the onset of substorms by a few to ˜20 minutes, i.e., significantly shorter than the gradient-curvature drift time of tens of keV ions. The time lag is of the order of the propagation time of reconnection-injected hot plasma jets to the premidnight plasmasphere and the substorm current wedge (SCW) to dusk. The observations confirm and expand on the previous results on the SAID features that negate the paradigm of voltage and current generators. Fast-time duskside SAPS/RC injections appear intimately related to a two-loop circuit of the substorm current wedge (SCW2L). We suggest that the poleward electric field inherent in the SCW2L circuit, which demands closure of the Region 1- and Region 2-sense field-aligned currents via meridional currents, is the ultimate cause of fast RC injections and SAPS on the duskside.

  16. Model of e-learning with electronic educational resources of new generation

    Directory of Open Access Journals (Sweden)

    A. V. Loban

    2017-01-01

    Full Text Available Purpose of the article: improving of scientific and methodical base of the theory of the е-learning of variability. Methods used: conceptual and logical modeling of the е-learning of variability process with electronic educational resource of new generation and system analysis of the interconnection of the studied subject area, methods, didactics approaches and information and communication technologies means. Results: the formalization complex model of the е-learning of variability with electronic educational resource of new generation is developed, conditionally decomposed into three basic components: the formalization model of the course in the form of the thesaurusclassifier (“Author of e-resource”, the model of learning as management (“Coordination. Consultation. Control”, the learning model with the thesaurus-classifier (“Student”. Model “Author of e-resource” allows the student to achieve completeness, high degree of didactic elaboration and structuring of the studied material in triples of variants: modules of education information, practical task and control tasks; the result of the student’s (author’s of e-resource activity is the thesaurus-classifier. Model of learning as management is based on the principle of personal orientation of learning in computer environment and determines the logic of interaction between the lecturer and the student when determining the triple of variants individually for each student; organization of a dialogue between the lecturer and the student for consulting purposes; personal control of the student’s success (report generation and iterative search for the concept of the class assignment in the thesaurus-classifier before acquiring the required level of training. Model “Student” makes it possible to concretize the learning tasks in relation to the personality of the student and to the training level achieved; the assumption of the lecturer about the level of training of a

  17. Critical Care Nurses Inadequately Assess SAPS II Scores of Very Ill Patients in Real Life

    Directory of Open Access Journals (Sweden)

    Andreas Perren

    2012-01-01

    Full Text Available Background. Reliable ICU severity scores have been achieved by various healthcare workers but nothing is known regarding the accuracy in real life of severity scores registered by untrained nurses. Methods. In this retrospective multicentre audit, three reviewers independently reassessed 120 SAPS II scores. Correlation and agreement of the sum-scores/variables among reviewers and between nurses and the reviewers’ gold standard were assessed globally and for tertiles. Bland and Altman (gold standard—nurses of sum scores and regression of the difference were determined. A logistic regression model identifying risk factors for erroneous assessments was calculated. Results. Correlation for sum scores among reviewers was almost perfect (mean ICC = 0.985. The mean (±SD nurse-registered SAPS II sum score was 40.3±20.2 versus 44.2±24.9 of the gold standard (32 points scores. The lowest agreement was found in high SAPS II tertiles for haemodynamics (k = 0.45–0.51. Conclusions. In real life, nurse-registered SAPS II scores of very ill patients are inaccurate. Accuracy of scores was not associated with nurses’ characteristics.

  18. Development of Two FhSAP2 Recombinant–Based Assays for Immunodiagnosis of Human Chronic Fascioliasis

    Science.gov (United States)

    Shin, Sun Hee; Hsu, Angel; Chastain, Holly M.; Cruz, Lorna A.; Elder, Eric S.; Sapp, Sarah G. H.; McAuliffe, Isabel; Espino, Ana M.; Handali, Sukwan

    2016-01-01

    In the United States, infection with Fasciola hepatica has been identified as an emerging disease, primarily in immigrants, refugees, and travelers. The laboratory test of choice for diagnosis of fascioliasis is detection of disease specific antibodies, most commonly uses excretory-secretory antigens for detection of IgG antibodies. Recently, recombinant proteins such as F. hepatica antigen (FhSAP2) have been used to detect IgG antibodies. The glutathione S-transferase (GST)–FhSAP2 recombinant antigen was used to develop Western blot (WB) and fluorescent bead-based (Luminex) assays to detect F. hepatica total IgG and IgG4 antibodies. The sensitivity and specificity of GST-FhSAP2 total IgG and IgG4 WB were similar at 94% and 98%, respectively. For the IgG Luminex assay, the sensitivity and specificity were 94% and 97%, and for the IgG4, the values were 100% and 99%, respectively. In conclusion, the GST-FhSAP2 antigen performs well in several assay formats and can be used for clinical diagnosis. PMID:27549636

  19. Development of Two FhSAP2 Recombinant-Based Assays for Immunodiagnosis of Human Chronic Fascioliasis.

    Science.gov (United States)

    Shin, Sun Hee; Hsu, Angel; Chastain, Holly M; Cruz, Lorna A; Elder, Eric S; Sapp, Sarah G H; McAuliffe, Isabel; Espino, Ana M; Handali, Sukwan

    2016-10-05

    In the United States, infection with Fasciola hepatica has been identified as an emerging disease, primarily in immigrants, refugees, and travelers. The laboratory test of choice for diagnosis of fascioliasis is detection of disease specific antibodies, most commonly uses excretory-secretory antigens for detection of IgG antibodies. Recently, recombinant proteins such as F. hepatica antigen (FhSAP2) have been used to detect IgG antibodies. The glutathione S-transferase (GST)-FhSAP2 recombinant antigen was used to develop Western blot (WB) and fluorescent bead-based (Luminex) assays to detect F. hepatica total IgG and IgG 4 antibodies. The sensitivity and specificity of GST-FhSAP2 total IgG and IgG 4 WB were similar at 94% and 98%, respectively. For the IgG Luminex assay, the sensitivity and specificity were 94% and 97%, and for the IgG 4 , the values were 100% and 99%, respectively. In conclusion, the GST-FhSAP2 antigen performs well in several assay formats and can be used for clinical diagnosis. © The American Society of Tropical Medicine and Hygiene.

  20. Surviving SAP Implementation in a Hospital

    OpenAIRE

    Cajiao Saenz, Juanita; Ramírez Robledo, Carlos Enrique

    2016-01-01

    On January 1, 2011, the Valle del Lili Foundation, a university hospital in Cali, Colombia, went from using paper for medical records and all associated clinical and administrative processes to managing everything electronically. This was a significant deviation from the industry norm since it was unusual for a hospital to simultaneously implement electronic medical records, computerized physician order entry, and enterprise resource planning. If they are implemented at all, they are generall...

  1. Analysis of the Tonle Sap Flood Pulse Based on Remote Sensing: how much does Tonle Sap Lake Affect the Mekong River Flood?

    Science.gov (United States)

    Qu, W.; Hu, N.; Fu, J.; Lu, J.; Lu, H.; Lei, T.; Pang, Z.; Li, X.; Li, L.

    2018-04-01

    The economic value of the Tonle Sap Lake Floodplain to Cambodia is among the highest provided to a nation by a single ecosystem around the world. The flow of Mekong River is the primary factor affecting the Tonle Sap Lake Floodplain. The Tonle Sap Lake also plays a very important role in regulating the downstream flood of Mekong River. Hence, it is necessary to understand its temporal changes of lake surface and water storage and to analyse its relation with the flood processes of Mekong River. Monthly lake surface and water storage from July 2013 to May 2014 were first monitored based on remote sensing data. The relationship between water surface and accumulative water storage change was then established. In combination with hydrological modelling results of Mekong River Basin, the relation between the lake's water storage and the runoff of Mekong River was analysed. It is found that the water storage has a sharp increase from September to December and, after reaching its maximum in December, water storage quickly decreases with a 38.8 billion m3 of drop in only half month time from December to January, while it keeps rather stable at a lower level in other months. There is a two months' time lag between the maximum lake water storage and the Mekong River peak flood, which shows the lake's huge flood regulation role to downstream Mekong River. It shows that this remote sensing approach is feasible and reliable in quantitative monitoring of data scarce lakes.

  2. Phloem sap collection from lettuce (Lactuca sativa L.): Methodology and yield.

    Science.gov (United States)

    van Helden, M; Tjallingii, W F; van Beek, T A

    1994-12-01

    Three methods to collect phloem sap on different lettuce lines were optimized and are described in detail. The success ratio for stylectomy of aphids was over 80% through the combination of a specially designed setup and electrical penetration graphs to monitor phloem sap ingestion. For unknown reasons on some lettuce lines stylets never showed sustained exudation. There were clear differences in stylet exudation between two aphid species on the same lettuce line. Honeydew collection in hexadecane made accurate quantitative analysis possible; samples were large and clean, but biotransformed. The EDTA chelation method produced large samples, but dilution, oxidation, and impurities from the wound surface reduced the reliability.

  3. Decreased SAP expression in T cells from patients with SLE contributes to early signaling abnormalities and reduced IL-2 production

    Science.gov (United States)

    Karampetsou, Maria P.; Comte, Denis; Kis-Toth, Katalin; Terhorst, Cox; Kyttaris, Vasileios C.; Tsokos, George C.

    2016-01-01

    T cells from patients with systemic lupus erythematosus (SLE) display a number of functions including increased early signaling events following engagement of the T cell receptor (TCR). Signaling lymphocytic activation molecule family (SLAMF) cell surface receptors and the X-chromosome-defined signaling lymphocytic activation molecule-associated protein (SAP) adaptor are important in the development of several immunocyte lineages and modulating immune response. Here we present evidence that SAP protein levels are decreased in T cells and in their main subsets isolated from 32 women and 3 men with SLE independently of disease activity. In SLE T cells the SAP protein is also subject to increased degradation by a caspase-3. Forced expression of SAP in SLE T cells simultaneously heightened IL-2 production, calcium (Ca2+) responses and tyrosine phosphorylation of a number of proteins. Exposure of normal T cells to SLE serum IgG, known to contain anti-CD3/TCR antibodies, resulted in SAP downregulation. We conclude that SLE T cells display reduced levels of the adaptor protein SAP probably as a result of continuous T cell activation and degradation by caspase-3. Restoration of SAP levels in SLE T cells corrects the overexcitable lupus T cell phenotype. PMID:27183584

  4. NK cell cytotoxicity mediated by 2B4 and NTB-A is dependent on SAP acting downstream of receptor phosphorylation

    Directory of Open Access Journals (Sweden)

    Stephan eMeinke

    2013-01-01

    Full Text Available 2B4 (CD244 and NK-T-B-antigen (NTB-A, CD352 are activating receptors on human NK cells and belong to the family of SLAM-related receptors. Engagement of these receptors leads to phosphorylation of their cytoplasmic tails and recruitment of the adapter proteins SAP and EAT-2. X-linked lymphoproliferative syndrome (XLP is a severe immunodeficiency that results from mutations in the SAP gene. 2B4 and NTB-A-mediated cytotoxicity are abrogated in XLP NK cells. To elucidate the molecular basis for this defect we analyzed early signaling events in SAP knockdown cells. Similar to XLP NK cells, knockdown of SAP in primary human NK cells leads to a reduction of 2B4 and NTB-A-mediated cytotoxicity. We found that early signaling events such as raft recruitment and receptor phosphorylation are not affected by the absence of SAP, indicating the defect in the absence of SAP is downstream of these events. In addition, knockdown of EAT-2 does not impair 2B4 or NTB-A-mediated cytotoxicity. Surprisingly, EAT-2 recruitment to both receptors is abrogated in the absence of SAP, revealing a novel cooperativity between these adapters.

  5. A survey of the use of electronic scientific information resources among medical and dental students

    Directory of Open Access Journals (Sweden)

    Aarnio Matti

    2006-05-01

    Full Text Available Abstract Background To evaluate medical and dental students' utilization of electronic information resources. Methods A web survey sent to 837 students (49.9% responded. Results Twenty-four per cent of medical students and ninteen per cent of dental students searched MEDLINE 2+ times/month for study purposes, and thiry-two per cent and twenty-four per cent respectively for research. Full-text articles were used 2+ times/month by thirty-three per cent of medical and ten per cent of dental students. Twelve per cent of respondents never utilized either MEDLINE or full-text articles. In multivariate models, the information-searching skills among students were significantly associated with use of MEDLINE and full-text articles. Conclusion Use of electronic resources differs among students. Forty percent were non-users of full-text articles. Information-searching skills are correlated with the use of electronic resources, but the level of basic PC skills plays not a major role in using these resources. The student data shows that adequate training in information-searching skills will increase the use of electronic information resources.

  6. Comparisons of xylem sap flow and water vapour flux at the stand level and derivation of canopy conductance for Scots pine

    Science.gov (United States)

    Granier, A.; Biron, P.; Köstner, B.; Gay, L. W.; Najjar, G.

    1996-03-01

    Simultaneous measurements of xylem sap flow and water vapour flux over a Scots pine ( Pinus sylvestris) forest (Hartheim, Germany), were carried out during the Hartheim Experiment (HartX), an intensive observation campaign of the international programme REKLIP. Sap flow was measured every 30 min using both radial constant heating (Granier, 1985) and two types of Cermak sap flowmeters installed on 24 trees selected to cover a wide range of the diameter classes of the stand (min 8 cm; max 17.5 cm). Available energy was high during the observation period (5.5 to 6.9 mm.day-1), and daily cumulated sap flow on a ground area basis varied between 2.0 and 2.7 mm day-1 depending on climate conditions. Maximum hourly values of sap flow reached 0.33 mm h-1, i.e., 230 W m-2. Comparisons of sap flow with water vapour flux as measured with two OPEC (One Propeller Eddy Correlation, University of Arizona) systems showed a time lag between the two methods, sap flow lagging about 90 min behind vapour flux. After taking into account this time lag in the sap flow data set, a good agreement was found between both methods: sap flow = 0.745* vapour flux, r 2 = 0.86. The difference between the two estimates was due to understory transpiration. Canopy conductance ( g c ) was calculated from sap flow measurements using the reverse form of Penman-Monteith equation and climatic data measured 4 m above the canopy. Variations of g c were well correlated ( r 2 = 0.85) with global radiation ( R) and vapour pressure deficit ( vpd). The quantitative expression for g c = f ( R, vpd) was very similar to that previously found with maritime pine ( Pinus pinaster) in the forest of Les Landes, South Western France.

  7. Growth of Verticillium longisporum in Xylem Sap of Brassica napus is Independent from Cultivar Resistance but Promoted by Plant Aging.

    Science.gov (United States)

    Lopisso, Daniel Teshome; Knüfer, Jessica; Koopmann, Birger; von Tiedemann, Andreas

    2017-09-01

    As Verticillium stem striping of oilseed rape (OSR), a vascular disease caused by Verticillium longisporum, is extending into new geographic regions and no control with fungicides exists, the demand for understanding mechanisms of quantitative resistance increases. Because V. longisporum is strictly limited to the xylem and resistance is expressed in the systemic stage post root invasion, we investigated a potential antifungal role of soluble constituents and nutritional conditions in xylem sap as determinants of cultivar resistance of OSR to V. longisporum. Assessment of biometric and molecular genetic parameters applied to describe V. longisporum resistance (net area under disease progress curve, stunting, stem thickness, plant biomass, and V. longisporum DNA content) showed consistent susceptibility of cultivar 'Falcon' in contrast to two resistant genotypes, 'SEM' and 'Aviso'. Spectrophotometric analysis revealed a consistently stronger in vitro growth of V. longisporum in xylem sap extracted from OSR compared with the water control. Further comparisons of fungal growth in xylem sap of different cultivars revealed the absence of constitutive or V. longisporum induced antifungal activity in the xylem sap of resistant versus susceptible genotypes. The similar growth of V. longisporum in xylem sap, irrespective of cultivar, infection with V. longisporum and xylem sap filtration, was correlated with about equal amounts of total soluble proteins in xylem sap from these treatments. Interestingly, compared with younger plants, xylem sap from older plants induced significantly stronger fungal growth. Growth enhancement of V. longisporum in xylem sap of aging plants was reflected by increased contents of carbohydrates, which was consistent in mock or V. longisporum-infected plants and independent from cultivar resistance. The improved nutritional conditions in the xylem of more mature plants may explain the late appearance of disease symptoms, which are observed only in

  8. BCM-95 and (2-hydroxypropyl)-β-cyclodextrin reverse autophagy dysfunction and deplete stored lipids in Sap C-deficient fibroblasts.

    Science.gov (United States)

    Tatti, Massimo; Motta, Marialetizia; Scarpa, Susanna; Di Bartolomeo, Sabrina; Cianfanelli, Valentina; Tartaglia, Marco; Salvioli, Rosa

    2015-08-01

    Saposin (Sap) C deficiency is a rare variant form of Gaucher disease caused by impaired Sap C expression or accelerated degradation, and associated with accumulation of glucosylceramide and other lipids in the endo/lysosomal compartment. No effective therapies are currently available for the treatment of Sap C deficiency. We previously reported that a reduced amount and enzymatic activity of cathepsin (Cath) B and Cath D, and defective autophagy occur in Sap C-deficient fibroblasts. Here, we explored the use of two compounds, BCM-95, a curcumin derivative, and (2-hydroxypropyl)-β-cyclodextrin (HP-β-CD), to improve lysosomal function of Sap C-deficient fibroblasts. Immunofluorescence and biochemical studies documented that each compound promotes an increase of the expression levels and activities of Cath B and Cath D, and efficient clearance of cholesterol (Chol) and ceramide (Cer) in lysosomes. We provide evidence that BCM-95 and HP-β-CD enhance lysosomal function promoting autophagic clearance capacity and lysosome reformation. Our findings suggest a novel pharmacological approach to Sap C deficiency directed to treat major secondary pathological aspects in this disorder. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  9. Access to electronic information resources by students of federal ...

    African Journals Online (AJOL)

    The paper discusses access to electronic information resources by students of Federal Colleges of Education in Eha-Amufu and Umunze. Descriptive survey design was used to investigate sample of 526 students. Sampling technique used was a Multi sampling technique. Data for the study were generated using ...

  10. Adoption and use of electronic information resources by medical ...

    African Journals Online (AJOL)

    This study investigated the adoption and use of electronic information resources by medical science students of the University of Benin. The descriptive survey research design was adopted for the study and 390 students provided the data. Data collected were analysed with descriptive Statistics(Simple percentage and ...

  11. Effects of Xylem-Sap Composition on Glassy-Winged Sharpshooter (Hemiptera: Cicadellidae) Egg Maturation on High- and Low-Quality Host Plants.

    Science.gov (United States)

    Sisterson, Mark S; Wallis, Christopher M; Stenger, Drake C

    2017-04-01

    Glassy-winged sharpshooters must feed as adults to produce mature eggs. Cowpea and sunflower are both readily accepted by the glassy-winged sharpshooter for feeding, but egg production on sunflower was reported to be lower than egg production on cowpea. To better understand the role of adult diet in egg production, effects of xylem-sap chemistry on glassy-winged sharpshooter egg maturation was compared for females confined to cowpea and sunflower. Females confined to cowpea consumed more xylem-sap than females held on sunflower. In response, females held on cowpea produced more eggs, had heavier bodies, and greater lipid content than females held on sunflower. Analysis of cowpea and sunflower xylem-sap found that 17 of 19 amino acids were more concentrated in cowpea xylem-sap than in sunflower xylem-sap. Thus, decreased consumption of sunflower xylem-sap was likely owing to perceived lower quality, with decreased egg production owing to a combination of decreased feeding and lower return per unit volume of xylem-sap consumed. Examination of pairwise correlation coefficients among amino acids indicated that concentrations of several amino acids within a plant species were correlated. Principal component analyses identified latent variables describing amino acid composition of xylem-sap. For females held on cowpea, egg maturation was affected by test date, volume of excreta produced, and principal components describing amino acid composition of xylem-sap. Principal component analyses aided in identifying amino acids that were positively or negatively associated with egg production, although determining causality with respect to key nutritional requirements for glassy-winged sharpshooter egg production will require additional testing. Published by Oxford University Press on behalf of Entomological Society of America 2017. This work is written by US Government employees and is in the public domain in the US.

  12. Molecular Pathogenesis of EBV Susceptibility in XLP as Revealed by Analysis of Female Carriers with Heterozygous Expression of SAP

    Science.gov (United States)

    Palendira, Umaimainthan; Low, Carol; Chan, Anna; Hislop, Andrew D.; Ho, Edwin; Phan, Tri Giang; Deenick, Elissa; Cook, Matthew C.; Riminton, D. Sean; Choo, Sharon; Loh, Richard; Alvaro, Frank; Booth, Claire; Gaspar, H. Bobby; Moretta, Alessandro; Khanna, Rajiv; Rickinson, Alan B.; Tangye, Stuart G.

    2011-01-01

    X-linked lymphoproliferative disease (XLP) is a primary immunodeficiency caused by mutations in SH2D1A which encodes SAP. SAP functions in signalling pathways elicited by the SLAM family of leukocyte receptors. A defining feature of XLP is exquisite sensitivity to infection with EBV, a B-lymphotropic virus, but not other viruses. Although previous studies have identified defects in lymphocytes from XLP patients, the unique role of SAP in controlling EBV infection remains unresolved. We describe a novel approach to this question using female XLP carriers who, due to random X-inactivation, contain both SAP+ and SAP− cells. This represents the human equivalent of a mixed bone marrow chimera in mice. While memory CD8+ T cells specific for CMV and influenza were distributed across SAP+ and SAP− populations, EBV-specific cells were exclusively SAP+. The preferential recruitment of SAP+ cells by EBV reflected the tropism of EBV for B cells, and the requirement for SAP expression in CD8+ T cells for them to respond to Ag-presentation by B cells, but not other cell types. The inability of SAP− clones to respond to Ag-presenting B cells was overcome by blocking the SLAM receptors NTB-A and 2B4, while ectopic expression of NTB-A on fibroblasts inhibited cytotoxicity of SAP− CD8+ T cells, thereby demonstrating that SLAM receptors acquire inhibitory function in the absence of SAP. The innovative XLP carrier model allowed us to unravel the mechanisms underlying the unique susceptibility of XLP patients to EBV infection in the absence of a relevant animal model. We found that this reflected the nature of the Ag-presenting cell, rather than EBV itself. Our data also identified a pathological signalling pathway that could be targeted to treat patients with severe EBV infection. This system may allow the study of other human diseases where heterozygous gene expression from random X-chromosome inactivation can be exploited. PMID:22069374

  13. AI User Support System for SAP ERP

    Science.gov (United States)

    Vlasov, Vladimir; Chebotareva, Victoria; Rakhimov, Marat; Kruglikov, Sergey

    2017-10-01

    An intelligent system for SAP ERP user support is proposed in this paper. It enables automatic replies on users’ requests for support, saving time for problem analysis and resolution and improving responsiveness for end users. The system is based on an ensemble of machine learning algorithms of multiclass text classification, providing efficient question understanding, and a special framework for evidence retrieval, providing the best answer derivation.

  14. Loss of Heterozygosity at an Unlinked Genomic Locus Is Responsible for the Phenotype of a Candida albicans sapsapsap6Δ Mutant ▿

    OpenAIRE

    Dunkel, Nico; Morschhäuser, Joachim

    2011-01-01

    The diploid genome of the pathogenic yeast Candida albicans exhibits a high degree of heterozygosity. Genomic alterations that result in a loss of heterozygosity at specific loci may affect phenotypes and confer a selective advantage under certain conditions. Such genomic rearrangements can also occur during the construction of C. albicans mutants and remain undetected. The SAP2 gene on chromosome R encodes a secreted aspartic protease that is induced and required for growth of C. albicans wh...

  15. [Time lag effect between poplar' s sap flow velocity and microclimate factors in agroforestry system in West Liaoning Province].

    Science.gov (United States)

    Di, Sun; Guan, De-xin; Yuan, Feng-hui; Wang, An-zhi; Wu, Jia-bing

    2010-11-01

    By using Granier's thermal dissipation probe, the sap flow velocity of the poplars in agroforestry system in west Liaoning was continuously measured, and the microclimate factors were measured synchronously. Dislocation contrast method was applied to analyze the sap flow velocity and corresponding air temperature, air humidity, net radiation, and vapor pressure deficit to discuss the time lag effect between poplar' s sap flow velocity and microclimate factors on sunny days. It was found that the poplar's sap flow velocity advanced of air temperature, air humidity, and vapor pressure deficit, and lagged behind net radiation. The sap flow velocity in June, July, August, and September was advanced of 70, 30, 50, and 90 min to air temperature, of 80, 30, 40, and 90 min to air humidity, and of 90, 50, 70, and 120 min to vapor pressure deficit, but lagged behind 10, 10, 40, and 40 min to net radiation, respectively. The time lag time of net radiation was shorter than that of air temperature, air humidity, and vapor pressure. The regression analysis showed that in the cases the time lag effect was contained and not, the determination coefficients between comprehensive microclimate factor and poplar's sap flow velocity were 0.903 and 0.855, respectively, indicating that when the time lag effect was contained, the determination coefficient was ascended by 2.04%, and thus, the simulation accuracy of poplar's sap flow velocity was improved.

  16. FOXP3 renders activated human regulatory T cells resistant to restimulation-induced cell death by suppressing SAP expression.

    Science.gov (United States)

    Katz, Gil; Voss, Kelsey; Yan, Toria F; Kim, Yong Chan; Kortum, Robert L; Scott, David W; Snow, Andrew L

    2018-05-01

    Restimulation-induced cell death (RICD) is an apoptotic program that regulates effector T cell expansion, triggered by repeated stimulation through the T cell receptor (TCR) in the presence of interleukin-2 (IL-2). Although CD4 + regulatory T cells (Tregs) consume IL-2 and experience frequent TCR stimulation, they are highly resistant to RICD. Resistance in Tregs is dependent on the forkhead box P3 (FOXP3) transcription factor, although the mechanism remains unclear. T cells from patients with X-linked lymphoproliferative disease (XLP-1), that lack the adaptor molecule SLAM-associated protein (SAP), are also resistant to RICD. Here we demonstrate that normal Tregs express very low levels of SAP compared to conventional T cells. FOXP3 reduces SAP expression by directly binding to and repressing the SH2D1A (SAP) promoter. Indeed, ectopic SAP expression restores RICD sensitivity in human FOXP3 + Tregs. Our findings illuminate the mechanism behind FOXP3-mediated RICD resistance in Tregs, providing new insight into their long-term persistence. Published by Elsevier Inc.

  17. Where Do Electronic Books Fit in the College Research Arsenal of Resources?

    Science.gov (United States)

    Barbier, Patricia

    2007-01-01

    Student use of electronic books has become an accepted supplement to traditional resources. Student use and satisfaction was monitored through an online course discussion board. Increased use of electronic books indicate this service is an accepted supplement to the print book collection.

  18. Measurement of respirable superabsorbent polyacrylate (SAP) dust by ethanol derivatization using gas chromatography-mass spectrometry (GC-MS) detection.

    Science.gov (United States)

    McCormack, Paul; Lemmo, John S; Macomber, Margaret; Holcomb, Mark L; Lieckfield, Robert

    2011-04-01

    Superabsorbent polyacrylate (SAP) is an important industrial chemical manufactured primarily as sodium polyacrylate but occasionally as potassium salt. It has many applications owing to its intrinsic physical property of very high water absorption, which can be more than 100 times it own weight. SAP is commonly used in disposable diapers and feminine hygiene products and is known by a number of synonyms-sodium polyacrylate, superabsorbent polyacrylate (SAP), polyacrylate absorbent (PA), and superabsorbent material (SAM). Germany and The Netherlands have adopted a nonbinding scientific guideline value 0.05 mg/m³ (8-hr time-weighted average, TWA) as the maximum allowable workplace concentration for the respirable dust of SAP (acrylate was developed and validated for the analysis of respirable superabsorbent polyacrylate dust collected on filter cassettes in the workplace environment. This method is an alternative to the commonly used sodium-based method, which is limited owing to potential interference by other sources of sodium from the workplace and laboratory environments. The alcohol derivatization method effectively eliminates sodium interference from several classes of sodium compounds, as shown by their purposeful introduction at two and six times the equivalent amount of SAP present in reference samples. The accuracy of the method, as determined by comparison with sodium analysis of known reference samples, was greater than 80% over the study range of 5-50 μg of SAP dust. The lower reporting limit of the method is 3.0 μg of SAP per sample, which is equivalent to 3 (μg/m³) for an 8-hr sampling period at the recommended flow rate of 2.2 L/min.

  19. Expression of the Aeluropus littoralis AlSAP Gene Enhances Rice Yield under Field Drought at the Reproductive Stage

    Directory of Open Access Journals (Sweden)

    Thaura Ghneim-Herrera

    2017-06-01

    Full Text Available We evaluated the yields of Oryza sativa L. ‘Nipponbare’ rice lines expressing a gene encoding an A20/AN1 domain stress-associated protein, AlSAP, from the halophyte grass Aeluropus littoralis under the control of different promoters. Three independent field trials were conducted, with drought imposed at the reproductive stage. In all trials, the two transgenic lines, RN5 and RN6, consistently out-performed non-transgenic (NT and wild-type (WT controls, providing 50–90% increases in grain yield (GY. Enhancement of tillering and panicle fertility contributed to this improved GY under drought. In contrast with physiological records collected during previous greenhouse dry-down experiments, where drought was imposed at the early tillering stage, we did not observe significant differences in photosynthetic parameters, leaf water potential, or accumulation of antioxidants in flag leaves of AlSAP-lines subjected to drought at flowering. However, AlSAP expression alleviated leaf rolling and leaf drying induced by drought, resulting in increased accumulation of green biomass. Therefore, the observed enhanced performance of the AlSAP-lines subjected to drought at the reproductive stage can be tentatively ascribed to a primed status of the transgenic plants, resulting from a higher accumulation of biomass during vegetative growth, allowing reserve remobilization and maintenance of productive tillering and grain filling. Under irrigated conditions, the overall performance of AlSAP-lines was comparable with, or even significantly better than, the NT and WT controls. Thus, AlSAP expression inflicted no penalty on rice yields under optimal growth conditions. Our results support the use of AlSAP transgenics to reduce rice GY losses under drought conditions.

  20. Metabolic activity of tree saps of different origin towards cultured human cells in the light of grade correspondence analysis and multiple regression modeling

    Directory of Open Access Journals (Sweden)

    Artur Wnorowski

    2017-06-01

    Full Text Available Tree saps are nourishing biological media commonly used for beverage and syrup production. Although the nutritional aspect of tree saps is widely acknowledged, the exact relationship between the sap composition, origin, and effect on the metabolic rate of human cells is still elusive. Thus, we collected saps from seven different tree species and conducted composition-activity analysis. Saps from trees of Betulaceae, but not from Salicaceae, Sapindaceae, nor Juglandaceae families, were increasing the metabolic rate of HepG2 cells, as measured using tetrazolium-based assay. Content of glucose, fructose, sucrose, chlorides, nitrates, sulphates, fumarates, malates, and succinates in sap samples varied across different tree species. Grade correspondence analysis clustered trees based on the saps’ chemical footprint indicating its usability in chemotaxonomy. Multiple regression modeling showed that glucose and fumarate present in saps from silver birch (Betula pendula Roth., black alder (Alnus glutinosa Gaertn., and European hornbeam (Carpinus betulus L. are positively affecting the metabolic activity of HepG2 cells.

  1. SAPS-Associated Explosive Brightening on the Duskside: A New Type of Onset-Like Disturbance

    Science.gov (United States)

    Henderson, M. G.; Morley, S. K.; Kepko, L. E.

    2018-01-01

    Quasiperiodic energetic particle injections have been observed at geosynchronous orbit on the duskside during a steady magnetospheric convection event. We examine high-resolution auroral imager data and ground magnetometer data associated with the first of these injections and conclude that it was not associated with classical substorm signatures. It is proposed that these injections are caused by the explosive nonlinear growth of a shear flow-ballooning instability in the region where subauroral polarization streams (SAPS) also occur. It is suggested that interchange will occur preferentially in the low-conductivity SAPS region since the magnetic Richardson number is lowest there and the "line-tying" effect will also be least stabilizing there. We propose that the observed particle injection signatures and auroral morphology constitute a new type of SAPS-associated explosive "onset-like" disturbance that can occur during intervals of strong convection.

  2. Metabolomics of tomato xylem sap during bacterial wilt reveals Ralstonia solanacearum produces abundant putrescine, a metabolite that accelerates wilt disease.

    Science.gov (United States)

    Lowe-Power, Tiffany M; Hendrich, Connor G; von Roepenack-Lahaye, Edda; Li, Bin; Wu, Dousheng; Mitra, Raka; Dalsing, Beth L; Ricca, Patrizia; Naidoo, Jacinth; Cook, David; Jancewicz, Amy; Masson, Patrick; Thomma, Bart; Lahaye, Thomas; Michael, Anthony J; Allen, Caitilyn

    2018-04-01

    Ralstonia solanacearum thrives in plant xylem vessels and causes bacterial wilt disease despite the low nutrient content of xylem sap. We found that R. solanacearum manipulates its host to increase nutrients in tomato xylem sap, enabling it to grow better in sap from infected plants than in sap from healthy plants. Untargeted GC/MS metabolomics identified 22 metabolites enriched in R. solanacearum-infected sap. Eight of these could serve as sole carbon or nitrogen sources for R. solanacearum. Putrescine, a polyamine that is not a sole carbon or nitrogen source for R. solanacearum, was enriched 76-fold to 37 µM in R. solanacearum-infected sap. R. solanacearum synthesized putrescine via a SpeC ornithine decarboxylase. A ΔspeC mutant required ≥ 15 µM exogenous putrescine to grow and could not grow alone in xylem even when plants were treated with putrescine. However, co-inoculation with wildtype rescued ΔspeC growth, indicating R. solanacearum produced and exported putrescine to xylem sap. Intriguingly, treating plants with putrescine before inoculation accelerated wilt symptom development and R. solanacearum growth and systemic spread. Xylem putrescine concentration was unchanged in putrescine-treated plants, so the exogenous putrescine likely accelerated disease indirectly by affecting host physiology. These results indicate that putrescine is a pathogen-produced virulence metabolite. © 2017 Society for Applied Microbiology and John Wiley & Sons Ltd.

  3. Genome-wide identification and characterization of stress-associated protein (SAP gene family encoding A20/AN1 zinc-finger proteins in Medicago truncatula

    Directory of Open Access Journals (Sweden)

    Zhou Yong

    2018-01-01

    Full Text Available Stress associated proteins (SAPs play important roles in developmental processes, responses to various stresses and hormone stimulation in plants. However, little is known about the SAP gene family in Medicago truncatula. In this study, a total of 17 MtSAP genes encoding A20/AN1 zinc-finger proteins were characterized. Out of these 17 genes, 15 were distributed over all 8 chromosomes at different densities, and two segmental duplication events were detected. The phylogenetic analysis of these proteins and their orthologs from Arabidopsis and rice suggested that they could be classified into five out of the seven groups of SAP family genes, with genes in the same group showing similar structures and conserved domains. The cis-elements of the MtSAP promoters were studied, and many cis-elements related to stress and plant hormone responses were identified. We also investigated the stress-responsive expression patterns of the MtSAP genes under various stresses, including drought, exposure to NaCl and cold. The qRT-PCR results showed that numerous MtSAP genes exhibited transcriptional responses to multiple abiotic stresses. These results lay the foundation for further functional characterization of SAP genes. To the best of our knowledge, this is the first report of a genome-wide analysis of the SAP gene family in M. truncatula.

  4. Green Synthesis of Three-Dimensional Hybrid N-Doped ORR Electro-Catalysts Derived from Apricot Sap

    Directory of Open Access Journals (Sweden)

    Ramesh Karunagaran

    2018-01-01

    Full Text Available Rapid depletion of fossil fuel and increased energy demand has initiated a need for an alternative energy source to cater for the growing energy demand. Fuel cells are an enabling technology for the conversion of sustainable energy carriers (e.g., renewable hydrogen or bio-gas into electrical power and heat. However, the hazardous raw materials and complicated experimental procedures used to produce electro-catalysts for the oxygen reduction reaction (ORR in fuel cells has been a concern for the effective implementation of these catalysts. Therefore, environmentally friendly and low-cost oxygen reduction electro-catalysts synthesised from natural products are considered as an attractive alternative to currently used synthetic materials involving hazardous chemicals and waste. Herein, we describe a unique integrated oxygen reduction three-dimensional composite catalyst containing both nitrogen-doped carbon fibers (N-CF and carbon microspheres (N-CMS synthesised from apricot sap from an apricot tree. The synthesis was carried out via three-step process, including apricot sap resin preparation, hydrothermal treatment, and pyrolysis with a nitrogen precursor. The nitrogen-doped electro-catalysts synthesised were characterised by SEM, TEM, XRD, Raman, and BET techniques followed by electro-chemical testing for ORR catalysis activity. The obtained catalyst material shows high catalytic activity for ORR in the basic medium by facilitating the reaction via a four-electron transfer mechanism.

  5. Green Synthesis of Three-Dimensional Hybrid N-Doped ORR Electro-Catalysts Derived from Apricot Sap.

    Science.gov (United States)

    Karunagaran, Ramesh; Coghlan, Campbell; Shearer, Cameron; Tran, Diana; Gulati, Karan; Tung, Tran Thanh; Doonan, Christian; Losic, Dusan

    2018-01-28

    Rapid depletion of fossil fuel and increased energy demand has initiated a need for an alternative energy source to cater for the growing energy demand. Fuel cells are an enabling technology for the conversion of sustainable energy carriers (e.g., renewable hydrogen or bio-gas) into electrical power and heat. However, the hazardous raw materials and complicated experimental procedures used to produce electro-catalysts for the oxygen reduction reaction (ORR) in fuel cells has been a concern for the effective implementation of these catalysts. Therefore, environmentally friendly and low-cost oxygen reduction electro-catalysts synthesised from natural products are considered as an attractive alternative to currently used synthetic materials involving hazardous chemicals and waste. Herein, we describe a unique integrated oxygen reduction three-dimensional composite catalyst containing both nitrogen-doped carbon fibers (N-CF) and carbon microspheres (N-CMS) synthesised from apricot sap from an apricot tree. The synthesis was carried out via three-step process, including apricot sap resin preparation, hydrothermal treatment, and pyrolysis with a nitrogen precursor. The nitrogen-doped electro-catalysts synthesised were characterised by SEM, TEM, XRD, Raman, and BET techniques followed by electro-chemical testing for ORR catalysis activity. The obtained catalyst material shows high catalytic activity for ORR in the basic medium by facilitating the reaction via a four-electron transfer mechanism.

  6. On the use of phloem sap δ13C to estimate canopy carbon discrimination

    Science.gov (United States)

    Rascher, Katherine; Máguas, Cristina; Werner, Christiane

    2010-05-01

    Although the carbon stable isotope composition (d13C) of bulk leaf material is a good integrative parameter of photosynthetic discrimination and can be used as a reliable ecological index of plant functioning; it is not a good tracer of short-term changes in photosynthetic discrimination. In contrast, d13C of phloem sap is potentially useful as an indicator of short-term changes in canopy photosynthetic discrimination. However, recent research indicates that d13C signatures may be substantially altered by metabolic processes downstream of initial leaf-level carbon fixation (e.g. post-photosynthetic fractionation). Accordingly, before phloem sap d13C can be used as a proxy for canopy level carbon discrimination an understanding of factors influencing the degree and magnitude of post-photosynthetic fractionation and how these vary between species is of paramount importance. In this study, we measured the d13C signature along the basipetal transport pathway in two co-occurring tree species in the field - an understory invasive exotic legume, Acacia longifolia, and a native pine, Pinus pinaster. We measured d13C of bulk leaf and leaf water soluble organic matter (WSOM), phloem sap sampled at two points along the plant axis and leaf and root dark respiration. In general, species differences in photosynthetic discrimination resulted in more enriched d13C values in the water-conserving P. pinaster relative to the water-spending A. longifolia. Post-photosynthetic fractionation led to differences in d13C of carbon pools along the plant axis with progressively more depleted d13C from the canopy to the trunk (~6.5 per mil depletion in A. longifolia and ~0.8per mil depletion in P. pinaster). Leaf and root respiration, d13C, were consistently enriched relative to putative substrates. We hypothesize that the pronounced enrichment of leaf respired CO2 relative to leaf WSOM may have left behind relatively depleted carbon to be loaded into the phloem resulting in d13C depletion

  7. Changes in the Proteome of Xylem Sap in Brassica oleracea in Response to Fusarium oxysporum Stress.

    Science.gov (United States)

    Pu, Zijing; Ino, Yoko; Kimura, Yayoi; Tago, Asumi; Shimizu, Motoki; Natsume, Satoshi; Sano, Yoshitaka; Fujimoto, Ryo; Kaneko, Kentaro; Shea, Daniel J; Fukai, Eigo; Fuji, Shin-Ichi; Hirano, Hisashi; Okazaki, Keiichi

    2016-01-01

    Fusarium oxysporum f.sp. conlutinans (Foc) is a serious root-invading and xylem-colonizing fungus that causes yellowing in Brassica oleracea. To comprehensively understand the interaction between F. oxysporum and B. oleracea, composition of the xylem sap proteome of the non-infected and Foc-infected plants was investigated in both resistant and susceptible cultivars using liquid chromatography-tandem mass spectrometry (LC-MS/MS) after in-solution digestion of xylem sap proteins. Whole genome sequencing of Foc was carried out and generated a predicted Foc protein database. The predicted Foc protein database was then combined with the public B. oleracea and B. rapa protein databases downloaded from Uniprot and used for protein identification. About 200 plant proteins were identified in the xylem sap of susceptible and resistant plants. Comparison between the non-infected and Foc-infected samples revealed that Foc infection causes changes to the protein composition in B. oleracea xylem sap where repressed proteins accounted for a greater proportion than those of induced in both the susceptible and resistant reactions. The analysis on the proteins with concentration change > = 2-fold indicated a large portion of up- and down-regulated proteins were those acting on carbohydrates. Proteins with leucine-rich repeats and legume lectin domains were mainly induced in both resistant and susceptible system, so was the case of thaumatins. Twenty-five Foc proteins were identified in the infected xylem sap and 10 of them were cysteine-containing secreted small proteins that are good candidates for virulence and/or avirulence effectors. The findings of differential response of protein contents in the xylem sap between the non-infected and Foc-infected samples as well as the Foc candidate effectors secreted in xylem provide valuable insights into B. oleracea-Foc interactions.

  8. Changes in the proteome of xylem sap in Brassica oleracea in response to Fusarium oxysporum stress

    Directory of Open Access Journals (Sweden)

    Zijing ePu

    2016-02-01

    Full Text Available Fusarium oxysporum f. sp. conlutinans (Foc is a serious root-invading and xylem-colonizing fungus that causes yellowing in Brassica oleracea. To comprehensively understand the interaction between F. oxysporum and B. oleracea, composition of the xylem sap proteome of the non-infected and Foc-infected plants was investigated in both resistant and susceptible cultivars using liquid chromatography-tandem mass spectrometry (LC-MS/MS after in-solution digestion of xylem sap proteins. Whole genome sequencing of Foc was carried out and generated a predicted Foc protein database. The predicted Foc protein database was then combined with the public B. oleracea and B. rapa protein databases downloaded from Uniprot and used for protein identification. About 200 plant proteins were identified in the xylem sap of susceptible and resistant plants. Comparison between the non-infected and Foc-infected samples revealed that Foc infection causes changes to the protein composition in B. oleracea xylem sap where repressed proteins accounted for a greater proportion than those of induced in both the susceptible and resistant reactions. The analysis on the proteins with concentration change >=2 fold indicated a large portion of up- and down-regulated proteins were those acting on carbohydrates. Proteins with leucine-rich repeats and legume lectin domains were mainly induced in both resistant and susceptible system, so was the case of thaumatins. Twenty-five Foc proteins were identified in the infected xylem sap and ten of them were cysteine-containing secreted small proteins that are good candidates for virulence and/or avirulence effectors. The findings of differential response of protein contents in the xylem sap between the non-infected and Foc-infected samples as well as the Foc candidate effectors secreted in xylem provide valuable insights into B. oleracea-Foc interactions.

  9. Glaucoma progression detection with frequency doubling technology (FDT) compared to standard automated perimetry (SAP) in the Groningen Longitudinal Glaucoma Study.

    Science.gov (United States)

    Wesselink, Christiaan; Jansonius, Nomdo M

    2017-09-01

    To determine the usefulness of frequency doubling perimetry (FDT) for progression detection in glaucoma, compared to standard automated perimetry (SAP). Data were used from 150 eyes of 150 glaucoma patients from the Groningen Longitudinal Glaucoma Study. After baseline, SAP was performed approximately yearly; FDT every other year. First and last visit had to contain both tests. Using linear regression, progression velocities were calculated for SAP (Humphrey Field Analyzer) mean deviation (MD) and FDT MD and the number of test locations with a total deviation probability below p glaucoma progression in patients who cannot perform SAP reliably. © 2017 The Authors Ophthalmic & Physiological Optics © 2017 The College of Optometrists.

  10. Comparison of sugars, iridoid glycosides and amino acids in nectar and phloem sap of Maurandya barclayana, Lophospermum erubescens, and Brassica napus.

    Science.gov (United States)

    Lohaus, Gertrud; Schwerdtfeger, Michael

    2014-01-01

    Floral nectar contains sugars and amino acids to attract pollinators. In addition, nectar also contains different secondary compounds, but little is understood about their origin or function. Does nectar composition reflect phloem composition, or is nectar synthesized and/or modified in nectaries? Studies where both, the nectar as well as the phloem sap taken from the same plant species were analyzed in parallel are rare. Therefore, phloem sap and nectar from different plant species (Maurandya barclayana, Lophospermum erubescens, and Brassica napus) were compared. Nectar was collected with microcapillary tubes and phloem sap with the laser-aphid-stylet technique. The nectar of all three plant species contained high amounts of sugars with different percentages of glucose, fructose, and sucrose, whereas phloem sap sugars consisted almost exclusively of sucrose. One possible reason for this could be the activity of invertases in the nectaries. The total concentration of amino acids was much lower in nectars than in phloem sap, indicating selective retention of nitrogenous solutes during nectar formation. Nectar amino acid concentrations were negatively correlated with the nectar volumes per flower of the different plant species. Both members of the tribe Antirrhineae (Plantaginaceae) M. barclayana and L. erubescens synthesized the iridoid glycoside antirrhinoside. High amounts of antirrhinoside were found in the phloem sap and lower amounts in the nectar of both plant species. The parallel analyses of nectar and phloem sap have shown that all metabolites which were found in nectar were also detectable in phloem sap with the exception of hexoses. Otherwise, the composition of both aqueous solutions was not the same. The concentration of several metabolites was lower in nectar than in phloem sap indicating selective retention of some metabolites. Furthermore, the existence of antirrhinoside in nectar could be based on passive secretion from the phloem.

  11. Comparison of sugars, iridoid glycosides and amino acids in nectar and phloem sap of Maurandya barclayana, Lophospermum erubescens, and Brassica napus.

    Directory of Open Access Journals (Sweden)

    Gertrud Lohaus

    Full Text Available BACKGROUND: Floral nectar contains sugars and amino acids to attract pollinators. In addition, nectar also contains different secondary compounds, but little is understood about their origin or function. Does nectar composition reflect phloem composition, or is nectar synthesized and/or modified in nectaries? Studies where both, the nectar as well as the phloem sap taken from the same plant species were analyzed in parallel are rare. Therefore, phloem sap and nectar from different plant species (Maurandya barclayana, Lophospermum erubescens, and Brassica napus were compared. METHODOLOGY AND PRINCIPAL FINDINGS: Nectar was collected with microcapillary tubes and phloem sap with the laser-aphid-stylet technique. The nectar of all three plant species contained high amounts of sugars with different percentages of glucose, fructose, and sucrose, whereas phloem sap sugars consisted almost exclusively of sucrose. One possible reason for this could be the activity of invertases in the nectaries. The total concentration of amino acids was much lower in nectars than in phloem sap, indicating selective retention of nitrogenous solutes during nectar formation. Nectar amino acid concentrations were negatively correlated with the nectar volumes per flower of the different plant species. Both members of the tribe Antirrhineae (Plantaginaceae M. barclayana and L. erubescens synthesized the iridoid glycoside antirrhinoside. High amounts of antirrhinoside were found in the phloem sap and lower amounts in the nectar of both plant species. CONCLUSIONS/SIGNIFICANCE: The parallel analyses of nectar and phloem sap have shown that all metabolites which were found in nectar were also detectable in phloem sap with the exception of hexoses. Otherwise, the composition of both aqueous solutions was not the same. The concentration of several metabolites was lower in nectar than in phloem sap indicating selective retention of some metabolites. Furthermore, the existence of

  12. Strategic Planning for Electronic Resources Management: A Case Study at Gustavus Adolphus College

    Science.gov (United States)

    Hulseberg, Anna; Monson, Sarah

    2009-01-01

    Electronic resources, the tools we use to manage them, and the needs and expectations of our users are constantly evolving; at the same time, the roles, responsibilities, and workflow of the library staff who manage e-resources are also in flux. Recognizing a need to be more intentional and proactive about how we manage e-resources, the…

  13. REVIEW OF MOODLE PLUGINS FOR DESIGNING MULTIMEDIA ELECTRONIC EDUCATIONAL RESOURCES FROM LANGUAGE DISCIPLINES

    Directory of Open Access Journals (Sweden)

    Anton M. Avramchuk

    2015-09-01

    Full Text Available Today the problem of designing multimedia electronic educational resources from language disciplines in Moodle is very important. This system has a lot of different, powerful resources, plugins to facilitate the learning of students with language disciplines. This article presents an overview and comparative analysis of the five Moodle plugins for designing multimedia electronic educational resources from language disciplines. There have been considered their key features and functionality in order to choose the best for studying language disciplines in the Moodle. Plugins are compared by a group of experts according to the criteria: efficiency, functionality and easy use. For a comparative analysis of the plugins it is used the analytic hierarchy process.

  14. Double strand RNA oral delivery methods to induce RNA interference in phloem and plant-sap-feeding insects

    Science.gov (United States)

    Phloem and plant sap feeding insect pests invade the integrity of crops and fruits to retrieve nutrients in the process damaging food productivity. Hemipteran insects account for a number of economically substantial pests of plants that cause damage to crops by feeding on phloem sap. Halyomorpha hal...

  15. ANALIZA PODPORE KADROVSKIH PROCESOV S SISTEMOM SAP V PODJETJU AVTENTA.SI D.O.O.

    OpenAIRE

    Vehovec, David

    2011-01-01

    V okviru diplomskega dela so z metodo prenove poslovnih procesov predstavljeni procesi zaposlovanja in razporejanja, upravljanja kadrovskih podatkov in prenehanja delovnega razmerja v podjetju Avtenta.si d.o.o. Na podlagi popisanih procesov je narejena analiza njihove podprtosti s sistemom SAP in predlog prenove. Le-ta vključuje modele prenovljenih procesov in prilagoditev sistema SAP do nivoja delujočega prototipa. V teoretičnem delu so opisana področja prenove poslovnih procesov, upravl...

  16. Pengaruh Pemahaman SAP, Pendidikan dan Pelatihan, serta Latar Belakang Pendidikan terhadap Penyusunan Laporan Keuangan Daerah pada Pemerintah Kota Medan.

    OpenAIRE

    Enho, Yohanes

    2011-01-01

    This skripsi is intended to (a) get a clear view about the effect of understanding SAP, training and workshop, also educational background, (b) calculate the effect of understanding SAP, training and workshop, also educational background to the way of making financial statement, (c) give some advices which may assist the City Government in solving its problems especially the discussed problem, that is the way of making financial statement which is affected by understanding SAP, training and w...

  17. 49 CFR 40.313 - Where is other information on SAP functions and the return-to-duty process found in this regulation?

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Where is other information on SAP functions and... on SAP functions and the return-to-duty process found in this regulation? You can find other information on the role and functions of SAPs in the following sections of this part: § 40.3—Definition. § 40...

  18. Modern ICT Tools: Online Electronic Resources Sharing Using Web ...

    African Journals Online (AJOL)

    Modern ICT Tools: Online Electronic Resources Sharing Using Web 2.0 and Its Implications For Library And Information Practice In Nigeria. ... The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader). If you would like more ...

  19. Antioxidant activity test on ambonese banana stem sap (Musa parasidiaca var. sapientum

    Directory of Open Access Journals (Sweden)

    Hendrik Setia Budi

    2015-12-01

    Full Text Available Background: Polymorphonuclear cells (PMN release oxygen free radicals or reactive oxygen species (ROS during inflammation. As a result, ROS level is higher than antioxidant level in our body during oxidative stress leading to prolong inflammation or continuous tissue damage. Indonesia, on the other hand, is a country with various herbal medicines. For instance, ambonese banana (Musa parasidiaca var. sapientum is often used as herbal medicine. Ambonese banana, moreover, has flavonoid, polyphenol, tannin, and saponin as antioxidants to reduce free radicals by transferring their hydrogen atom. Medicine used to reduce the impact of free radicals is known as antioxidant. Antioxidant is proved to accelerate wound healing. Purpose: This research aims to analyze the effects of the antioxidant activity of Ambonese banana stem sap extract. Method: Antioxidant activities in this research were examined with 1,1-Diphenyl-2-picryl-hidrazyl (DPPH method by reacting with stable radical compounds. Spectrophotometry with a wavelength of 517 nm was used to measure absorption results shown in purple. The absorption results then were calculated by IC50 reduction activity. Result: There were significant differences of Ambonese banana stem sap antioxidant activity (p50%. Conclusion: Ambonese banana stem sap extract has antioxidant activities.

  20. Paraformaldehyde pellet not necessary in vacuum-pumped maple sap system

    Science.gov (United States)

    H. Clay Smith; Carter B. Gibbs

    1970-01-01

    In a study of sugar maple sap collection through a vacuum-pumped plastic tubing system, yields were compared between tapholes in which paraformaldehyde pellets were used and tapholes without pellets, Use of the pellets did not increase yield.

  1. INTEGRATION OF THE SAP CONCEPT IN THE EMPLOYEE ASSESSMENT OF TRAVEL AGENCIES IN SUCEAVA COUNTY THROUGH MYSTERY SHOPPING TYPE METHODS

    Directory of Open Access Journals (Sweden)

    Cristian Valentin HAPENCIUC

    2014-07-01

    Full Text Available Being on a positive trend and addressing to a market that is less willing to compromise, the tourism industry develops a highly complex content, represented by various organizations and services, having as a main objective meeting the expectations of consumers of tourism services and reporting to the challenges of contemporary dynamics generated by the emergence of new information technologies. To respond effectively to these issues, tourism requires among other things a modern HR management. For travel agencies, human resources are the main asset of the company that serves to implement the entity's objectives. The most important qualities of the travel agent are polite attitude, promptness, sagacity and firmness. However, the ability to display with celerity their own capabilities - intellectual, psycho-motivational and persuasive - represents the quintessence of the travel agent profession. When we refer to these features, in the universal tourism language we talk about SAP concept: Speed, Accuracy, Politeness. Therefore, the major objective of this study aims to assess the employees of travel agencies from Suceava County in terms of SAP components using three different methods of qualitative research: Mystery Shopping, Mystery Calling and Mystery Emailing.

  2. Map of important transactions and master data in SAP ERP

    OpenAIRE

    Schermann, Michael

    2015-01-01

    This image represents the most important transactions and master data in SAP ERP as a tube map. As such, it covers most of the content of Magal & Word (2012) Integrated Business Processes with ERP Systems. Wiley, Hoboken, NJ, USA.

  3. Energy control in industry ''case of SAP Olympic''. ''Pre- energy diagnosis of SAP Olympic: optimization of consumption of electricity and compressed air''

    International Nuclear Information System (INIS)

    Zemba, Ouamsibiri Ernest

    2007-01-01

    This document is a report of a training course to graduate university degree in electronic engineering. It tackles the important question of the competitiveness of Burkina Faso societies in the UEMOA zone. The cost of energy is very high for these societies. This situation affects the distribution of their products. In this case the societies have to optimize their energy consumption. A company as SAP Olympic is supplied energy by a primary tension of 15 KV and a contractual demand of 750 kWh. This society works on 24 hours a day, from Monday to Saturday. Its energy consumption raised and was accentuated by the lack of measuring devices, controls, adjustments and monitoring. That is also caused the one's age of the equipment and installations: all that involves over consumptions and thus penalties of going beyond the contractual demand. It would thus be necessary to have an electric diagram, to have numerical analyzers of electricity consumption and to subscribe has a higher power in order to carry out savings of time of maintenance, availability of production, equipment and staff safety and in order to avoid the penalties of going beyond [fr

  4. Taloushallinto SAP ERP 6.0 - järjestelmässä : Tehtäväpaketin laatiminen

    OpenAIRE

    Holappa, Mikko

    2015-01-01

    Tämän opinnäytetyön tarkoituksena oli oppimateriaalin luominen taloushallinnon opiskelijoille SAP ERP 6.0 - järjestelmään. Työn toimeksiantaja oli Oulun ammattikorkeakoulun liiketalouden yksikkö, joka käyttää opetuksessaan SAP ERP - järjestelmää. SAP AG:n omien harjoitusten lisäksi oli tarve saada lisää tehtäviä kurssilla käytettäväksi. Kehittämistehtävä rajattiin käsittämään ostoprosessi (MM), myyntiprosessi (SD) sekä pääkirja. Opinnäytetyöstä rajattiin pois muut taloushallinnon prosessit. ...

  5. Sorption kinetics of superabsorbent polymers (SAPs) in fresh Portland cement-based pastes visualized and quantified by neutron radiography and correlated to the progress of cement hydration

    Energy Technology Data Exchange (ETDEWEB)

    Schroefl, Christof, E-mail: christof.schroefl@tu-dresden.de [Technische Universität Dresden, Fakultät Bauingenieurwesen, Institut für Baustoffe, DE-01062 Dresden (Germany); Mechtcherine, Viktor [Technische Universität Dresden, Fakultät Bauingenieurwesen, Institut für Baustoffe, DE-01062 Dresden (Germany); Vontobel, Peter; Hovind, Jan; Lehmann, Eberhard [Paul Scherrer Institut, Laboratory for Neutron Scattering and Imaging, CH-5232 Villigen/AG (Switzerland)

    2015-09-15

    Water sorption of two superabsorbent polymers in cement-based pastes has been characterized by neutron radiography. Cement pastes with W/C of 0.25 and 0.50 and one additionally containing silica fume (W/C = 0.42) were investigated. The SAPs differed in their inherent sorption kinetics in extracted cement pore solution (SAP 1: self-releasing; SAP 2: retentive). Desorption from SAP 1 started very early after paste preparation. Hence, its individual non-retentiveness governs its behavior only. SAP 2 released water into all matrices, but its kinetics were different. In the paste with the highest W/C, some moderate water release was recorded from the beginning. In the other two pastes, SAP 2 retained its stored liquid during the dormant period, i.e., up to the percolation threshold. Intense desorption then set in and continued throughout the acceleration period. These findings explain the pronouncedly higher efficiency of SAP 2 as internal curing admixture as compared to SAP 1.

  6. Sorption kinetics of superabsorbent polymers (SAPs) in fresh Portland cement-based pastes visualized and quantified by neutron radiography and correlated to the progress of cement hydration

    International Nuclear Information System (INIS)

    Schroefl, Christof; Mechtcherine, Viktor; Vontobel, Peter; Hovind, Jan; Lehmann, Eberhard

    2015-01-01

    Water sorption of two superabsorbent polymers in cement-based pastes has been characterized by neutron radiography. Cement pastes with W/C of 0.25 and 0.50 and one additionally containing silica fume (W/C = 0.42) were investigated. The SAPs differed in their inherent sorption kinetics in extracted cement pore solution (SAP 1: self-releasing; SAP 2: retentive). Desorption from SAP 1 started very early after paste preparation. Hence, its individual non-retentiveness governs its behavior only. SAP 2 released water into all matrices, but its kinetics were different. In the paste with the highest W/C, some moderate water release was recorded from the beginning. In the other two pastes, SAP 2 retained its stored liquid during the dormant period, i.e., up to the percolation threshold. Intense desorption then set in and continued throughout the acceleration period. These findings explain the pronouncedly higher efficiency of SAP 2 as internal curing admixture as compared to SAP 1

  7. THE MODEL OF LINGUISTIC TEACHERS’ COMPETENCY DEVELOPMENT ON DESIGNING MULTIMEDIA ELECTRONIC EDUCATIONAL RESOURCES IN THE MOODLE SYSTEM

    Directory of Open Access Journals (Sweden)

    Anton M. Avramchuk

    2017-10-01

    Full Text Available The article is devoted to the problem of developing the competency of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system. The concept of "the competence of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system" is justified and defined. Identified and characterized the components by which the levels of the competency development of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system should be assessed. Developed a model for the development of the competency of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system, which is based on the main scientific approaches, used in adult education, and consists of five blocks: target, informative, technological, diagnostic and effective.

  8. Developing Humanities Collections in the Digital Age: Exploring Humanities Faculty Engagement with Electronic and Print Resources

    Science.gov (United States)

    Kachaluba, Sarah Buck; Brady, Jessica Evans; Critten, Jessica

    2014-01-01

    This article is based on quantitative and qualitative research examining humanities scholars' understandings of the advantages and disadvantages of print versus electronic information resources. It explores how humanities' faculty members at Florida State University (FSU) use print and electronic resources, as well as how they perceive these…

  9. Decreased SAP Expression in T Cells from Patients with Systemic Lupus Erythematosus Contributes to Early Signaling Abnormalities and Reduced IL-2 Production.

    Science.gov (United States)

    Karampetsou, Maria P; Comte, Denis; Kis-Toth, Katalin; Terhorst, Cox; Kyttaris, Vasileios C; Tsokos, George C

    2016-06-15

    T cells from patients with systemic lupus erythematosus (SLE) display a number of abnormalities, including increased early signaling events following engagement of the TCR. Signaling lymphocytic activation molecule family cell surface receptors and the X-chromosome-defined signaling lymphocytic activation molecule-associated protein (SAP) adaptor are important in the development of several immunocyte lineages and modulating the immune response. We present evidence that SAP protein levels are decreased in T cells and in their main subsets isolated from 32 women and three men with SLE, independent of disease activity. In SLE T cells, SAP protein is also subject to increased degradation by caspase-3. Forced expression of SAP in SLE T cells normalized IL-2 production, calcium (Ca(2+)) responses, and tyrosine phosphorylation of a number of proteins. Exposure of normal T cells to SLE serum IgG, known to contain anti-CD3/TCR Abs, resulted in SAP downregulation. We conclude that SLE T cells display reduced levels of the adaptor protein SAP, probably as a result of continuous T cell activation and degradation by caspase-3. Restoration of SAP levels in SLE T cells corrects the overexcitable lupus T cell phenotype. Copyright © 2016 by The American Association of Immunologists, Inc.

  10. [Responses of sap flow to natural rainfall and continuous drought of tree species growing on bedrock outcrops].

    Science.gov (United States)

    Zhang, Hui Ling; Ding, Ya Li; Chen, Hong Song; Wang, Ke Lin; Nie, Yun Peng

    2018-04-01

    This study focused on bedrock outcrops, a very common habitat in karst region of southwest China. To reveal the responses of plant transpiration to natural rainfall and continuous drought, two tree species typical to this habitat, Radermachera sinica and Triadica rotundifolia, were selected as test materials. A rainout shelter was used to simulate continuous drought. The sap flow dynamics were monitored using the method of Granier's thermal dissipation probe (TDP). Our results showed that sap flow density increased to different degrees after rain in different stages of the growing season. Sap flow density of the deciduous species T. rotundifolia was always higher than that of the semi-deciduous species R. sinica. After two months without rainfall input, both species exhibited no obvious decrease in sap flow density, indicating that rainfall was not the dominant source for their water uptake, at least in the short-term. Based on the regression relationships between sap flow density and meteorological factors before and after rainfall, as well as at different stages of continuous drought, we found that the dynamics of meteorological factors contributed little to plant transpiration. The basic transpiration characteristics of both species were not changed in the circumstance of natural rainfall and short-term continuous drought, which would be closely related to the special water storage environments of bedrock outcrops and the reliance on deep water sources by tree species.

  11. Sugars of the unfermented sap and the wine from the oil palm, Elaeis guinensis, tree.

    Science.gov (United States)

    Eze, M O; Ogan, U

    1988-01-01

    The sugar composition of the unfermented sap from oil palm (Elaeis guinensis) trees growing in the plantations of the Nigerian Institute for Oil Palm Research, Benin City, has been determined. While sucrose concentration ranges from 9.59 to 10.59% (w/v) in the pure unfermented sap, that of either glucose or fructose is much less than 1% (w/v) (0.13-0.73% w/v). Raffinose occurs in traces only (0.13-0.35 w/v). These results were derived from our improved methods which eliminate completely, or reduce to a bare minimum, fermentation of the sap during collection. The variation with time of storage of the individual sugars in the sap during fermentation to form palm wine reveals that, as sucrose steadily decreases, fructose reaches a peak at 1.51% (w/v) at the 9th hour, and thereafter declines, while glucose and raffinose remain continuously low; all sugars disappear beyond the 33rd hour. Concomittantly, pH decreases from pH 6.60 at zero time and stabilizes at pH 3.30 after 48 h, while titrable acidity increases continuously up until the 96th hour. These changes account for the variations in the quality of palm wine during storages.

  12. Beyond Enterprise Resource Planning (ERP): The Next Generation Enterprise Resource Planning Environment

    Science.gov (United States)

    2012-02-01

    systems can provide these business functions. • ERP system: an enterprise-wide commercial off-the-shelf (COTS) software product (e.g., SAP and Oracle...are with two Tier 1 ERP software vendors: Oracle and SAP .16 Moreover, the implementation contracts for these larger ERP system investments were only...documents/FIAR_Plan_November_2011.pdf. 16 compliance was accomplished. In the current environment, DoD’s two ERP software vendors— Oracle and SAP —and the

  13. Maple sap predominant microbial contaminants are correlated with the physicochemical and sensorial properties of maple syrup.

    Science.gov (United States)

    Filteau, Marie; Lagacé, Luc; Lapointe, Gisèle; Roy, Denis

    2012-03-01

    Maple sap processing and microbial contamination are significant aspects that affect maple syrup quality. In this study, two sample sets from 2005 and 2008 were used to assess the maple syrup quality variation and its relationship to microbial populations, with respect to processing, production site and harvesting period. The abundance of maple sap predominant bacteria (Pseudomonas fluorescens group and two subgroups, Rahnella spp., Janthinobacterium spp., Leuconostoc mesenteroides) and yeast (Mrakia spp., Mrakiella spp.,Guehomyces pullulans) was assessed by quantitative PCR. Maple syrup properties were analyzed by physicochemical and sensorial methods. Results indicate that P. fluorescens, Mrakia spp., Mrakiella spp. G. pullulans and Rahnella spp. are stable contaminants of maple sap, as they were found for every production site throughout the flow period. Multiple factor analysis reports a link between the relative abundance of P. fluorescens group and Mrakia spp. in maple sap with maple and vanilla odor as well as flavor of maple syrup. This evidence supports the contribution of these microorganisms or a consortium of predominant microbial contaminants to the characteristic properties of maple syrup. Copyright © 2011 Elsevier B.V. All rights reserved.

  14. 49 CFR 40.291 - What is the role of the SAP in the evaluation, referral, and treatment process of an employee who...

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false What is the role of the SAP in the evaluation... Process § 40.291 What is the role of the SAP in the evaluation, referral, and treatment process of an employee who has violated DOT agency drug and alcohol testing regulations? (a) As a SAP, you are charged...

  15. The effect of cisplatin administration on certain trace elements homeostasis in rats and the protective effect of silver birch (Betula pendula) sap.

    Science.gov (United States)

    Muselin, Florin; Dumitrescu, Eugenia; Berbecea, Adina; Doma, Alexandru Octavian; Brezovan, Diana; Savici, Jelena; Trif, Alexandra; Cristina, Romeo Teodor

    2018-02-07

    A clinically active structure with known antitumor activities is cisplatin (CDDP), but this it comes with toxicity characteristics which can be faded by the beneficial effects of Silver birch (Betula pendula) sap. We aimed to assess the cisplatin activity on: Mn, Mg, Cu, Fe and Zn homeostasis in rats and to observe the effect of birch sap. Healthy Wistar rats (n = 10/group) were divided in four groups: Control: receiving 1 mL saline I.P. way + water; E1: cisplatin 20 mg kgbw -1 , I.P.; E2: cisplatin 20 mg kgbw -1 , I.P. + birch sap and Control sap group: 1 mL saline I.P. + birch sap. Blood was collected: at the trial's start and after 48 h, and blood and organs (liver, kidney and spleen) for the cytoarchitecture investigation and readings were sampled after seven days. Samples were processed in nitric acid by microwave digestion and readings were completed by flame atomic absorption spectroscopy, the outcomes being statistically analyzed by ANOVA. Cisplatin produced a significant imbalance in the trace elements homeostasis, the birch sap administration recovering them usual homeostasis status. Comparatively with the Control, rats exposed to cisplatin presented a not significant (p > 0.05) decrease of Zn (-26.74%) and Mg (-10.25%), a significant (p  0.05) increase of Mn (+28.16%). Birch sap administration after Cisplatin was followed by restoration or nevertheless significant increase (p sap against diverse cisplatin deleterious side-effects. Copyright © 2018 Elsevier GmbH. All rights reserved.

  16. Analysis of piping systems by finite element method using code SAP-IV

    International Nuclear Information System (INIS)

    Cizelj, L.; Ogrizek, D.

    1987-01-01

    Due to extensive and multiple use of the computer code SAP-IV we have decided to install it on VAX 11/750 machine. Installation required a large quantity of programming due to great discrepancies between the CDC (the original program version) and the VAX. Testing was performed basically in the field of pipe elements, based on a comparison between results obtained with the codes PSAFE2, DOCIJEV, PIPESD and SAP -V. Besides, the model of reactor pressure vessel with 3-D thick shell elements was done. The capabilities show good agreement with the results of other programs mentioned above. Along with the package installation, the graphical postprocessors being developed for mesh plotting. (author)

  17. Better prognostic marker in ICU - APACHE II, SOFA or SAP II!

    Science.gov (United States)

    Naqvi, Iftikhar Haider; Mahmood, Khalid; Ziaullaha, Syed; Kashif, Syed Mohammad; Sharif, Asim

    2016-01-01

    This study was designed to determine the comparative efficacy of different scoring system in assessing the prognosis of critically ill patients. This was a retrospective study conducted in medical intensive care unit (MICU) and high dependency unit (HDU) Medical Unit III, Civil Hospital, from April 2012 to August 2012. All patients over age 16 years old who have fulfilled the criteria for MICU admission were included. Predictive mortality of APACHE II, SAP II and SOFA were calculated. Calibration and discrimination were used for validity of each scoring model. A total of 96 patients with equal gender distribution were enrolled. The average APACHE II score in non-survivors (27.97+8.53) was higher than survivors (15.82+8.79) with statistically significant p value (discrimination power than SAP II and SOFA.

  18. Synthesis and processing of sphingolipid activator protein-2 (SAP-2) in cultured human fibroblasts

    International Nuclear Information System (INIS)

    Fujibayashi, S.; Wenger, D.A.

    1986-01-01

    Sphingolipid activator proteins (SAP) are relatively small molecular weight proteins that stimulate the enzymatic hydrolysis of sphingolipids in the presence of specific lysosomal hydrolases. SAP-2 has previously been demonstrated to activate the hydrolysis of glucosylceramide, galactosylceramide, and, possibly, sphingomyelin. Using monospecific rabbit antibodies against human spleen SAP-2, the synthesis and processing of SAP-2 were studied in cultured human fibroblasts. When [ 35 S]methionine was presented in the medium to control human cells for 4 h, five major areas of radiolabeling were found. These had apparent molecular weights of 73,000, 68,000, 50,000, 12,000, and 9000. Further studies indicated that the major extracellular product in normal cells given NH4Cl along with the [ 35 S]methionine and in medium from cultures from patients with I cell disease had an apparent molecular weight of 73,000. The Mr = 68,000 and 73,000 species can be converted to a species with an apparent molecular weight of 50,000 by the action of endoglycosidase F. After labeling cells for 1 h followed by a 1-h chase, the Mr = 12,000 and 9000 species appear. Treatment of the immunoprecipitated mixture with endoglycosidase F resulted in conversion of these species to one band with an apparent molecular weight of 7600. These studies indicate that this relatively low molecular weight protein is rapidly synthesized from a relatively large molecular weight highly glycosylated precursor

  19. Electronic resource management systems a workflow approach

    CERN Document Server

    Anderson, Elsa K

    2014-01-01

    To get to the bottom of a successful approach to Electronic Resource Management (ERM), Anderson interviewed staff at 11 institutions about their ERM implementations. Among her conclusions, presented in this issue of Library Technology Reports, is that grasping the intricacies of your workflow-analyzing each step to reveal the gaps and problems-at the beginning is crucial to selecting and implementing an ERM. Whether the system will be used to fill a gap, aggregate critical data, or replace a tedious manual process, the best solution for your library depends on factors such as your current soft

  20. Clinical characteristics and SAP scintigraphic findings in 10 patients with AGel amyloidosis.

    Science.gov (United States)

    Rowczenio, Dorota; Tennent, Glenys A; Gilbertson, Janet; Lachmann, Helen J; Hutt, David F; Bybee, Alison; Hawkins, Philip N; Gillmore, Julian D

    2014-12-01

    The clinical features of hereditary gelsolin (AGel) amyloidosis include corneal lattice dystrophy, distal sensorimotor, cranial neuropathy and cutis laxa. To date, four mutations of the gelsolin (GSN) gene encoding the following variants have been identified as the cause of this malady; p.D214N, p.D214Y, p.G194R and p.N211K (this nomenclature includes the 27-residue signal peptide). Interestingly, the latter two variants are associated exclusively with a renal amyloidosis phenotype. Here we report the clinical features in 10 patients with AGel amyloidosis associated with the p.D214N mutation, all of whom underwent whole body (123)I-SAP scintigraphy and were followed up in a single UK Centre for a prolonged period. Two patients, from the same kindred presented with proteinuria; eight subjects had a characteristic AGel amyloidosis phenotype including cranial neuropathy and/or corneal lattice dystrophy. (123)I-SAP scintigraphy revealed substantial renal amyloid deposits in all 10 patients, including those with preserved renal function, and usually without tracer uptake into other visceral organs. (123)I-SAP scintigraphy is a non-invasive technique that aids early diagnosis of patients with this rare disease, especially those who lack a family history and/or present with an unusual clinical phenotype.

  1. Impact of Laurel Wilt, Caused by Raffaelea lauricola, on Leaf Gas Exchange and Xylem Sap Flow in Avocado, Persea americana.

    Science.gov (United States)

    Ploetz, Randy C; Schaffer, Bruce; Vargas, Ana I; Konkol, Joshua L; Salvatierra, Juanpablo; Wideman, Ronney

    2015-04-01

    Laurel wilt, caused by Raffaelea lauricola, is a destructive disease of avocado (Persea americana). The susceptibility of different cultivars and races was examined previously but more information is needed on how this host responds to the disease. In the present study, net CO2 assimilation (A), stomatal conductance of H2O (gs), transpiration (E), water use efficiency (WUE), and xylem sap flow rates were assessed in cultivars that differed in susceptibility. After artificial inoculation with R. lauricola, there was a close relationship between symptom development and reductions in A, gs, E, WUE, and mean daily sap flow in the most susceptible cultivar, 'Russell', and significantly greater disease and lower A, gs, E, WUE, and sap flow rates were usually detected after 15 days compared with the more tolerant 'Brogdon' and 'Marcus Pumpkin'. Significant differences in preinoculation A, gs, E, and WUE were generally not detected among the cultivars but preinoculation sap flow rates were greater in Russell than in Brogdon and Marcus Pumpkin. Preinoculation sap flow rates and symptom severity for individual trees were correlated at the end of an experiment (r=0.46), indicating that a plant's susceptibility to laurel wilt was related to its ability to conduct water. The potential management of this disease with clonal rootstocks that reduce sap flow rates is discussed.

  2. Dams on Mekong tributaries as significant contributors of hydrological alterations to the Tonle Sap Floodplain in Cambodia

    Science.gov (United States)

    Arias, M. E.; Piman, T.; Lauri, H.; Cochrane, T. A.; Kummu, M.

    2014-12-01

    River tributaries have a key role in the biophysical functioning of the Mekong Basin. Of particular interest are the Sesan, Srepok, and Sekong (3S) rivers, which contribute nearly a quarter of the total Mekong discharge. Forty two dams are proposed in the 3S, and once completed they will exceed the active storage of China's large dam cascade in the Upper Mekong. Given their proximity to the Lower Mekong floodplains, the 3S dams could alter the flood-pulse hydrology driving the productivity of downstream ecosystems. Therefore, the main objective of this study was to quantify how hydropower development in the 3S, together with definite future (DF) plans for infrastructure development through the basin, would alter the hydrology of the Tonle Sap's Floodplain, the largest wetland in the Mekong and home to one of the most productive inland fisheries in the world. We coupled results from four numerical models representing the basin's surface hydrology, water resources development, and floodplain hydrodynamics. The scale of alterations caused by hydropower in the 3S was compared with the basin's DF scenario driven by the Upper Mekong dam cascade. The DF or the 3S development scenarios could independently increase Tonle Sap's 30-day minimum water levels by 30 ± 5 cm and decrease annual water level fall rates by 0.30 ± 0.05 cm day-1. When analyzed together (DF + 3S), these scenarios are likely to eliminate all baseline conditions (1986-2000) of extreme low water levels, a particularly important component of Tonle Sap's environmental flows. Given the ongoing trends and large economic incentives in the hydropower business in the region, there is a high possibility that most of the 3S hydropower potential will be exploited and that dams will be built even in locations where there is a high risk of ecological disruption. Hence, retrofitting current designs and operations to promote sustainable hydropower practices that optimize multiple river services - rather than just

  3. Electronic Resource Management System. Vernetzung von Lizenzinformationen

    Directory of Open Access Journals (Sweden)

    Michaela Selbach

    2014-12-01

    Full Text Available In den letzten zehn Jahren spielen elektronische Ressourcen im Bereich der Erwerbung eine zunehmend wichtige Rolle: Eindeutig lässt sich hier ein Wandel in den Bibliotheken (fort vom reinen Printbestand zu immer größeren E-Only-Beständen feststellen. Die stetig wachsende Menge an E-Ressourcen und deren Heterogenität stellt Bibliotheken vor die Herausforderung, die E-Ressourcen effizient zu verwalten. Nicht nur Bibliotheken, sondern auch verhandlungsführende Institutionen von Konsortial- und Allianzlizenzen benötigen ein geeignetes Instrument zur Verwaltung von Lizenzinformationen, welches den komplexen Anforderungen moderner E-Ressourcen gerecht wird. Die Deutsche Forschungsgemeinschaft (DFG unterstützt ein Projekt des Hochschulbibliothekszentrums des Landes Nordrhein-Westfalen (hbz, der Universitätsbibliothek Freiburg, der Verbundzentrale des Gemeinsamen Bibliotheksverbundes (GBV und der Universitätsbibliothek Frankfurt, in dem ein bundesweit verfügbares Electronic Ressource Managementsystem (ERMS aufgebaut werden soll. Ein solches ERMS soll auf Basis einer zentralen Knowledge Base eine einheitliche Nutzung von Daten zur Lizenzverwaltung elektronischer Ressourcen auf lokaler, regionaler und nationaler Ebene ermöglichen. Statistische Auswertungen, Rechteverwaltung für alle angeschlossenen Bibliotheken, kooperative Datenpflege sowie ein über standardisierte Schnittstellen geführter Datenaustausch stehen bei der Erarbeitung der Anforderungen ebenso im Fokus wie die Entwicklung eines Daten- und Funktionsmodells. In the last few years the importance of electronic resources in library acquisitions has increased significantly. There has been a shift from mere print holdings to both e- and print combinations and even e-only subscriptions. This shift poses a double challenge for libraries: On the one hand they have to provide their e-resource collections to library users in an appealing way, on the other hand they have to manage these

  4. 49 CFR 40.303 - What happens if the SAP believes the employee needs additional treatment, aftercare, or support...

    Science.gov (United States)

    2010-10-01

    ... recommended services. You may also make use of SAP and employee assistance program (EAP) services in assisting... 49 Transportation 1 2010-10-01 2010-10-01 false What happens if the SAP believes the employee needs additional treatment, aftercare, or support group services even after the employee returns to...

  5. Targeted mutagenesis of the Sap47 gene of Drosophila: Flies lacking the synapse associated protein of 47 kDa are viable and fertile

    Directory of Open Access Journals (Sweden)

    Huber Saskia

    2004-04-01

    Full Text Available Abstract Background Conserved proteins preferentially expressed in synaptic terminals of the nervous system are likely to play a significant role in brain function. We have previously identified and molecularly characterized the Sap47 gene which codes for a novel synapse associated protein of 47 kDa in Drosophila. Sequence comparison identifies homologous proteins in numerous species including C. elegans, fish, mouse and human. First hints as to the function of this novel protein family can be obtained by generating mutants for the Sap47 gene in Drosophila. Results Attempts to eliminate the Sap47 gene through targeted mutagenesis by homologous recombination were unsuccessful. However, several mutants were generated by transposon remobilization after an appropriate insertion line had become available from the Drosophila P-element screen of the Bellen/Hoskins/Rubin/Spradling labs. Characterization of various deletions in the Sap47 gene due to imprecise excision of the P-element identified three null mutants and three hypomorphic mutants. Null mutants are viable and fertile and show no gross structural or obvious behavioural deficits. For cell-specific over-expression and "rescue" of the knock-out flies a transgenic line was generated which expresses the most abundant transcript under the control of the yeast enhancer UAS. In addition, knock-down of the Sap47 gene was achieved by generating 31 transgenic lines expressing Sap47 RNAi constructs, again under UAS control. When driven by a ubiquitously expressed yeast transcription factor (GAL4, Sap47 gene suppression in several of these lines is highly efficient resulting in residual SAP47 protein concentrations in heads as low as 6% of wild type levels. Conclusion The conserved synaptic protein SAP47 of Drosophila is not essential for basic synaptic function. The Sap47 gene region may be refractory to targeted mutagenesis by homologous recombination. RNAi using a construct linking genomic DNA to anti

  6. Comparison of Threshold Saccadic Vector Optokinetic Perimetry (SVOP) and Standard Automated Perimetry (SAP) in Glaucoma. Part II: Patterns of Visual Field Loss and Acceptability.

    Science.gov (United States)

    McTrusty, Alice D; Cameron, Lorraine A; Perperidis, Antonios; Brash, Harry M; Tatham, Andrew J; Agarwal, Pankaj K; Murray, Ian C; Fleck, Brian W; Minns, Robert A

    2017-09-01

    We compared patterns of visual field loss detected by standard automated perimetry (SAP) to saccadic vector optokinetic perimetry (SVOP) and examined patient perceptions of each test. A cross-sectional study was done of 58 healthy subjects and 103 with glaucoma who were tested using SAP and two versions of SVOP (v1 and v2). Visual fields from both devices were categorized by masked graders as: 0, normal; 1, paracentral defect; 2, nasal step; 3, arcuate defect; 4, altitudinal; 5, biarcuate; and 6, end-stage field loss. SVOP and SAP classifications were cross-tabulated. Subjects completed a questionnaire on their opinions of each test. We analyzed 142 (v1) and 111 (v2) SVOP and SAP test pairs. SVOP v2 had a sensitivity of 97.7% and specificity of 77.9% for identifying normal versus abnormal visual fields. SAP and SVOP v2 classifications showed complete agreement in 54% of glaucoma patients, with a further 23% disagreeing by one category. On repeat testing, 86% of SVOP v2 classifications agreed with the previous test, compared to 91% of SAP classifications; 71% of subjects preferred SVOP compared to 20% who preferred SAP. Eye-tracking perimetry can be used to obtain threshold visual field sensitivity values in patients with glaucoma and produce maps of visual field defects, with patterns exhibiting close agreement to SAP. Patients preferred eye-tracking perimetry compared to SAP. This first report of threshold eye tracking perimetry shows good agreement with conventional automated perimetry and provides a benchmark for future iterations.

  7. No association between GSTM1 and GSTT1 genetic polymorphisms and susceptibility to opium sap dependence.

    Science.gov (United States)

    Saify, Khyber; Khalighinasab, Mohammad Rashid; Saadat, Mostafa

    2016-03-01

    Glutathione S-transferases (GSTs; EC: 2.5.1.18) are a ubiquitous family of eukaryotic and prokaryotic phase II metabolic isozymes. Genes encoding GSTM1 (OMIM: 138350), and GSTT1 (OMIM: 600436) are members of class mu and theta, respectively. The most common polymorphism in the GSTM1 is a deletion of the whole GSTM1 gene with a lack of enzyme activity. A homozygous deletion in the GSTT1 has also been reported (null genotypes of GSTT1). The aim of the present study was to investigate the association between GSTM1 and GSTT1 polymorphisms and risk of dependency to opium sap. The present study was performed in Shiraz (southern Iran). In total, 71 males dependent to opium sap and 590 healthy males (as a control group) were included in this study. The genotypes of GSTM1 and GSTT1 polymorphisms were determined by PCR. Our data indicate that neither GSTM1 (OR=0.78, 95% CI: 0.47-1.27, P=0.325) nor GSTT1 (OR=1.25, 95% CI: 0.70-2.21, P=0.442) null genotypes significantly associated with the risk of opium sap dependence. There is no additive effect of the null genotypes of GSTT1 and GSTM1 in relation to the risk of dependency to opium sap. The present study indicated that the null genotypes of GSTT1 and GSTM1 are not risk factor for opium sap dependence.

  8. The Electron Microscopy Outreach Program: A Web-based resource for research and education.

    Science.gov (United States)

    Sosinsky, G E; Baker, T S; Hand, G; Ellisman, M H

    1999-01-01

    We have developed a centralized World Wide Web (WWW)-based environment that serves as a resource of software tools and expertise for biological electron microscopy. A major focus is molecular electron microscopy, but the site also includes information and links on structural biology at all levels of resolution. This site serves to help integrate or link structural biology techniques in accordance with user needs. The WWW site, called the Electron Microscopy (EM) Outreach Program (URL: http://emoutreach.sdsc.edu), provides scientists with computational and educational tools for their research and edification. In particular, we have set up a centralized resource containing course notes, references, and links to image analysis and three-dimensional reconstruction software for investigators wanting to learn about EM techniques either within or outside of their fields of expertise. Copyright 1999 Academic Press.

  9. Technical Communicator: A New Model for the Electronic Resources Librarian?

    Science.gov (United States)

    Hulseberg, Anna

    2016-01-01

    This article explores whether technical communicator is a useful model for electronic resources (ER) librarians. The fields of ER librarianship and technical communication (TC) originated and continue to develop in relation to evolving technologies. A review of the literature reveals four common themes for ER librarianship and TC. While the…

  10. Customization of a Severity of Illness Score Using Local Electronic Medical Record Data.

    Science.gov (United States)

    Lee, Joon; Maslove, David M

    2017-01-01

    Severity of illness (SOI) scores are traditionally based on archival data collected from a wide range of clinical settings. Mortality prediction using SOI scores tends to underperform when applied to contemporary cases or those that differ from the case-mix of the original derivation cohorts. We investigated the use of local clinical data captured from hospital electronic medical records (EMRs) to improve the predictive performance of traditional severity of illness scoring. We conducted a retrospective analysis using data from the Multiparameter Intelligent Monitoring in Intensive Care II (MIMIC-II) database, which contains clinical data from the Beth Israel Deaconess Medical Center in Boston, Massachusetts. A total of 17 490 intensive care unit (ICU) admissions with complete data were included, from 4 different service types: medical ICU, surgical ICU, coronary care unit, and cardiac surgery recovery unit. We developed customized SOI scores trained on data from each service type, using the clinical variables employed in the Simplified Acute Physiology Score (SAPS). In-hospital, 30-day, and 2-year mortality predictions were compared with those obtained from using the original SAPS using the area under the receiver-operating characteristics curve (AUROC) as well as the area under the precision-recall curve (AUPRC). Test performance in different cohorts stratified by severity of organ injury was also evaluated. Most customized scores (30 of 39) significantly outperformed SAPS with respect to both AUROC and AUPRC. Enhancements over SAPS were greatest for patients undergoing cardiovascular surgery and for prediction of 2-year mortality. Custom models based on ICU-specific data provided better mortality prediction than traditional SAPS scoring using the same predictor variables. Our local data approach demonstrates the value of electronic data capture in the ICU, of secondary uses of EMR data, and of local customization of SOI scoring. © The Author(s) 2015.

  11. Detection of Candida albicans Sap2 in cancer patient serum samples by an indirect competitive enzyme-linked immunosorbent assay for the diagnosis of candidiasis

    OpenAIRE

    Yicun Wang; Xiang Gao; J U Zhi gang; Jingyuan Liu; Shuai Dong; Li Wang

    2013-01-01

    Background: The secreted aspartyl proteinases 2 (Sap2) of Candida albicans (C. albicans) is a potential marker of candididasis. It is a virulence factor associated with adherence and tissue invasion. Aim: In order to detect Sap2 in clinical sera, we developed an indirect competitive enzyme-linked immunosorbent assay (ELISA). Materials and Methods: Polyclonal antibodies were produced for Sap2 by injecting Sap2 into a New Zealand White inbred rabbit. They could be used at a dilution exceeding 1...

  12. Heterocomplexes of mannose-binding lectin and the pentraxins PTX3 or SAP trigger cross-activation of the complement system

    DEFF Research Database (Denmark)

    Ma, Ying Jie; Doni, Andrea; Skjødt, Mikkel-Ole

    2011-01-01

    The long pentraxin 3 (PTX3), serum amyloid P component (SAP) and C-reactive protein (CRP) belong to the pentraxin family of pattern recognition molecules involved in tissue homeostasis and innate immunity. They interact with C1q from the classical complement pathway. Whether this also occurs via...... the analogous mannose-binding lectin (MBL) from the lectin complement pathway is unknown. Thus, we investigated the possible interaction between MBL and the pentraxins. We report that MBL bound PTX3 and SAP partly via its collagen-like domain, but not CRP. MBL:PTX3 complex formation resulted in recruitment of C......1q, but this was not seen for the MBL:SAP complex. However, both MBL:PTX3 and MBL:SAP complexes enhanced C4 and C3 deposition and opsonophagocytosis of Candida albicans by polymorphonuclear leukocytes. Interaction between MBL and PTX3 lead to communication between the lectin and classical complement...

  13. Predictive Performance of the Simplified Acute Physiology Score (SAPS) II and the Initial Sequential Organ Failure Assessment (SOFA) Score in Acutely Ill Intensive Care Patients

    DEFF Research Database (Denmark)

    Granholm, Anders; Møller, Morten Hylander; Kragh, Mette

    2016-01-01

    PURPOSE: Severity scores including the Simplified Acute Physiology Score (SAPS) II and the Sequential Organ Failure Assessment (SOFA) score are used in intensive care units (ICUs) to assess disease severity, predict mortality and in research. We aimed to assess the predictive performance of SAPS II...... compared the discrimination of SAPS II and initial SOFA scores, compared the discrimination of SAPS II in our cohort with the original cohort, assessed the calibration of SAPS II customised to our cohort, and compared the discrimination for 90-day mortality vs. in-hospital mortality for both scores....... Discrimination was evaluated using areas under the receiver operating characteristics curves (AUROC). Calibration was evaluated using Hosmer-Lemeshow's goodness-of-fit Ĉ-statistic. RESULTS: AUROC for in-hospital mortality was 0.80 (95% confidence interval (CI) 0.77-0.83) for SAPS II and 0.73 (95% CI 0...

  14. Effects of dates pulp extract and palm sap (Phoenix dactylifera L.) on gastrointestinal transit activity in healthy rats.

    Science.gov (United States)

    Souli, Abdellaziz; Sebai, Hichem; Rtibi, Kaïs; Chehimi, Latifa; Sakly, Mohsen; Amri, Mohamed; El-Benna, Jamel

    2014-07-01

    The current study was performed to measure the chemical composition and the effects of dates pulp extract and palm sap on gastrointestinal transit (GIT) activity in healthy adult rats. In this respect, male Wistar rats fasted for 24 hours were used and received per orally (p.o.) sodium chloride (NaCl) (0,9%) (control group) or various doses of dates pulp extract (150 and 300 mg/kg, body weight [b.w.]) and palm sap (0.4 and 4 mL/kg, b.w.). Two other groups of rats (batch tests) received, respectively, clonidine (an alpha-2 adrenergic agonist, 1 mg/kg, b.w.) and yohimbine (an alpha-2 adrenergic antagonist, 2mg/kg, b.w.). Chemical analysis showed that the dates pulp extract is more rich in sugars and minerals, especially potassium and sucrose, as compared with palm sap composition. On the other hand, in vivo study showed that the aqueous dates pulp extract significantly, and dose dependently, increased the GIT activity while the palm sap slightly increased it. Moreover, a converse effect has been observed using clonidine (decreased 68%) and yohimbine (increased 33%) on the GIT activity. These findings suggest that dates pulp extract and palm sap have a stimulating effect on GIT activity in rats and confirm their use in traditional Tunisian medicine for the treatment of constipation.

  15. Utilization of chitosan as an antimicrobial agent for pasteurized palm sap (Borassus flabellifer Linn.) during storage.

    Science.gov (United States)

    Naknean, Phisut; Jutasukosol, Keawta; Mankit, Theerarat

    2015-02-01

    The objective of this research was to assess the potential of chitosan for improvement the quality of pasteurized palm sap during storage. First, the effect of chitosan content on sensory attributes was investigated to select suitable concentration of chitosan for further study. Fresh palm sap was enriched with chitosan at various concentrations (0-2 g/L) and pasteurized at 80 °C for 10 min, consequently evaluated by consumers. It was found that samples added chitosan in the range of 0-1.00 g/L were considered acceptable. Thus, the addition chitosan in the concentration of 0-1.00 g/L was chosen for further study. The sample without chitosan addition was used as a control sample. Each selected sample was determined for their qualities during storage at 1 week interval. It was found that lightness and transmittance values of all samples tended to increase during storage. Lower PPO and invertase activity were observed in all chitosan-treated samples compared to control sample. Chitosan could minimize the loss of sucrose and the increase in glucose and fructose content during storage. In addition, an increase in chitosan concentration resulted in the increase in DPPH radical scavenging activity. Furthermore, the addition of chitosan could retard the development of microorganism during storage as demonstrated by lower microbial loads compared to control sample. It can be concluded that a combination of pasteurization with chitosan addition (0.50 g/L) and low temperature storage could preserve palm sap for approximately 6 weeks. Thus, the incorporation of chitosan in palm sap could be used as an alternative way to extend shelf life of pasteurized palm sap.

  16. Comparison of mortality prediction models and validation of SAPS II in critically ill burns patients.

    Science.gov (United States)

    Pantet, O; Faouzi, M; Brusselaers, N; Vernay, A; Berger, M M

    2016-06-30

    Specific burn outcome prediction scores such as the Abbreviated Burn Severity Index (ABSI), Ryan, Belgian Outcome of Burn Injury (BOBI) and revised Baux scores have been extensively studied. Validation studies of the critical care score SAPS II (Simplified Acute Physiology Score) have included burns patients but not addressed them as a cohort. The study aimed at comparing their performance in a Swiss burns intensive care unit (ICU) and to observe whether they were affected by a standardized definition of inhalation injury. We conducted a retrospective cohort study, including all consecutive ICU burn admissions (n=492) between 1996 and 2013: 5 epochs were defined by protocol changes. As required for SAPS II calculation, stays burned (TBSA) and inhalation injury (systematic standardized diagnosis since 2006). Study epochs were compared (χ2 test, ANOVA). Score performance was assessed by receiver operating characteristic curve analysis. SAPS II performed well (AUC 0.89), particularly in burns burns <40% TBSA. Ryan and BOBI scores were least accurate, as they heavily weight inhalation injury.

  17. Assurance due to the Usage of Two ERP Methods: Microsoft Dynamics AX and SAP

    Directory of Open Access Journals (Sweden)

    Soobia Saeed

    2018-04-01

    Full Text Available A speculation-based resource organising technique aids agencies in routing information across many industrial components. Organisation functions through IT (Information Technology with the use of the latest technology helps HR (Human Resources increase gross sales and beyond. The problem associated with an industry organizational tool is that it needs to share data from the MRP (Material Requirements Planning system with financial accounting, customer relationships, the supply chain or other applications with the use of the latest technologies. Organisations cannot easily acquire choices, whatever ERP (Enterprise Resource Planning devices are made for their organisation.In this research paper, we performedand maintained QA (Quality Assurance using two ERPs are Microsoft Design AX and SAP (Software and Application. Selecting the best ERP technique is never easy. These sort of options are likely to be a really expensive investment decision along with lifetime costs which include a huge amount of money. In this research article, we have highlighted the important elements of the investigation tasks – the biological materials or groupings, steps, treatment options or applications, and also strategies within the assignment. This study can be a resourceful approach to get the essential details through the most effective way possible. This is caused by truth migration; you can use technique personalisation and employee education thoroughly, making use of the types of programs and talks that take a couple of months to more comprehensive period of time to perform. This research study hasfound that ERP is better than the currently used Supply Chain module. Key Words: Supply Chain, Quality Assurance, Microsoft Design AX,

  18. Whole body amyloid deposition imaging by 123I-SAP scintigraphy

    NARCIS (Netherlands)

    van Rheenen, Ronald; Glaudemans, Andor; Hazenberg, Bouke

    2011-01-01

    Amyloidosis is the name of a group of diseases characterized by extracellular deposition of amyloid fibrils. Deposition of amyloid can be localized or systemic. The 123I-SAP-scan can be used to image extent and distribution of amyloid deposition in patients with systemic AA, AL and ATTR amyloidosis.

  19. Restimulation-induced T-cell death through NTB-A/SAP signaling pathway is impaired in tuberculosis patients with depressed immune responses.

    Science.gov (United States)

    Hernández Del Pino, Rodrigo E; Pellegrini, Joaquín M; Rovetta, Ana I; Peña, Delfina; Álvarez, Guadalupe I; Rolandelli, Agustín; Musella, Rosa M; Palmero, Domingo J; Malbran, Alejandro; Pasquinelli, Virginia; García, Verónica E

    2017-09-01

    Production of IFN-γ contributes to host defense against Mycobacterium tuberculosis (Mtb) infection. We previously demonstrated that Signaling lymphocytic activation molecule-associated protein (SAP) expression on cells from tuberculosis (TB) patients was inversely correlated with IFN-γ production. Here we first investigated the role of NK, T- and B-cell antigen (NTB-A)/SAP pathway in the regulation of Th1 response against Mtb. Upon antigen stimulation, NTB-A phosphorylation rapidly increases and afterwards modulates IFN-γ and IL-17 secretion. To sustain a healthy immune system, controlled expansion and contraction of lymphocytes, both during and after an adaptive immune response, is essential. Besides, restimulation-induced cell death (RICD) results in an essential homeostatic mechanism for precluding excess T-cell accumulation and associated immunopathology during the course of certain infections. Accordingly, we found that the NTB-A/SAP pathway was required for RICD during active tuberculosis. In low responder (LR) TB patients, impaired RICD was associated with diminished FASL levels, IL-2 production and CD25 high expression after cell-restimulation. Interestingly, we next observed that SAP mediated the recruitment of the Src-related kinase FYNT, only in T cells from LR TB patients that were resistant to RICD. Together, we showed that the NTB-A/SAP pathway regulates T-cell activation and RICD during human TB. Moreover, the NTB-A/SAP/FYNT axis promotes polarization to an unfavorable Th2-phenotype.

  20. Conformational Plasticity of the Cell-Penetrating Peptide SAP As Revealed by Solid-State 19F-NMR and Circular Dichroism Spectroscopies.

    Science.gov (United States)

    Afonin, Sergii; Kubyshkin, Vladimir; Mykhailiuk, Pavel K; Komarov, Igor V; Ulrich, Anne S

    2017-07-13

    The cell-penetrating peptide SAP, which was designed as an amphipathic poly-l-proline helix II (PPII), was suggested to self-assemble into regular fibrils that are relevant for its internalization. Herein we have analyzed the structure of SAP in the membrane-bound state by solid-state 19 F-NMR, which revealed other structural states, in addition to the expected surface-aligned PPII. Trifluoromethyl-bicyclopentyl-glycine (CF 3 -Bpg) and two rigid isomers of trifluoromethyl-4,5-methanoprolines (CF 3 -MePro) were used as labels for 19 F-NMR analysis. The equilibria between different conformations of SAP were studied and were found to be shifted by the substituents at Pro-11. Synchrotron-CD results suggested that substituting Pro-11 by CF 3 -MePro governed the coil-to-PPII equilibrium in solution and in the presence of a lipid bilayer. Using CD and 19 F-NMR, we examined the slow kinetics of the association of SAP with membranes and the dependence of the SAP conformational dynamics on the lipid composition. The peptide did not bind to lipids in the solid ordered phase and aggregated only in the liquid ordered "raft"-like bilayers. Self-association could not be detected in solution or in the presence of liquid disordered membranes. Surface-bound amphipathic SAP in a nonaggregated state was structured as a mixture of nonideal extended conformations reflecting the equilibrium already present in solution, i.e., before binding to the membrane.

  1. Combining sap flow and eddy covariance approaches to derive stomatal and non-stomatal O3 fluxes in a forest stand

    International Nuclear Information System (INIS)

    Nunn, A.J.; Cieslik, S.; Metzger, U.; Wieser, G.; Matyssek, R.

    2010-01-01

    Stomatal O 3 fluxes to a mixed beech/spruce stand (Fagus sylvatica/Picea abies) in Central Europe were determined using two different approaches. The sap flow technique yielded the tree-level transpiration, whereas the eddy covariance method provided the stand-level evapotranspiration. Both data were then converted into stomatal ozone fluxes, exemplifying this novel concept for July 2007. Sap flow-based stomatal O 3 flux was 33% of the total O 3 flux, whereas derivation from evapotranspiration rates in combination with the Penman-Monteith algorithm amounted to 47%. In addition to this proportional difference, the sap flow-based assessment yielded lower levels of stomatal O 3 flux and reflected stomatal regulation rather than O 3 exposure, paralleling the daily courses of canopy conductance for water vapor and eddy covariance-based total stand-level O 3 flux. The demonstrated combination of sap flow and eddy covariance approaches supports the development of O 3 risk assessment in forests from O 3 exposure towards flux-based concepts. - Combined tree sap flow and eddy covariance-based methodologies yield stomatal O 3 flux as 33% in total stand flux.

  2. Nucleotides, micro- and macro-nutrients, limonoids, flavonoids, and hydroxycinnamates composition in the phloem sap of sweet orange.

    Science.gov (United States)

    Hijaz, Faraj; Manthey, John A; Van der Merwe, Deon; Killiny, Nabil

    2016-06-02

    Currently, the global citrus production is declining due to the spread of Huanglongbing (HLB). HLB, otherwise known as citrus greening, is caused by Candidatus Liberibacter asiaticus (CLas) and is transmitted by the Asian citrus psyllids (ACP), Diaphorina citri Kuwayama. ACP transmits CLas bacterium while feeding on the citrus phloem sap. Multiplication of CLas in the phloem of citrus indicates that the sap contains all the essential nutrients needed for CLas. In this study, we investigated the micro- and macro-nutrients, nucleotides, and others secondary metabolites of phloem sap from pineapple sweet orange. The micro- and macro-nutrients were analyzed using inductively coupled plasma-mass spectroscopy (ICP-MS) and inductively coupled plasma-optical emission spectroscopy (ICP-OES). Nucleotides and other secondary metabolites analysis was accomplished by reversed phase HPLC coupled with UV, fluorescence detection, or negative mode electrospray ionization mass spectrometry (ESI-MS). Calcium (89 mM) was the highest element followed by potassium (38.8 mM) and phosphorous (24 mM). Magnesium and sulfur were also abundant and their concentrations were 15 and 9 mM, respectively. The rest of the elements were found in low amounts (sap.

  3. Groundwater discharge and phosphorus dynamics in a flood-pulse system: Tonle Sap Lake, Cambodia

    Science.gov (United States)

    Burnett, William C.; Wattayakorn, Gullaya; Supcharoen, Ratsirin; Sioudom, Khamfeuane; Kum, Veasna; Chanyotha, Supitcha; Kritsananuwat, Rawiwan

    2017-06-01

    Tonle Sap Lake (Cambodia), a classic example of a "flood pulse" system, is the largest freshwater lake in SE Asia, and is reported to have one of the highest freshwater fish productions anywhere. During the dry season (November-April) the lake drains through a tributary to the Mekong River. The flow in the connecting tributary completely reverses during the wet monsoon (May-October), adding huge volumes of water back to the lake, increasing its area about six fold. The lake is likely phosphorus limited and we hypothesized that groundwater discharge, including recirculated lake water, may represent an important source of P and other nutrients. To address this question, we surveyed hundreds of kilometers of the lake for natural 222Rn (radon), temperature, conductivity, GPS coordinates and water depth. All major inorganic nutrients and phosphorus species were evaluated by systematic sampling throughout the lake. Results showed that there were radon hotspots, all at the boundaries between the permanent lake and the floodplain, indicating likely groundwater inputs. A radon mass balance model indicates that the groundwater flow to Tonle Sap Lake is approximately 10 km3/yr, about 25% as large as the floodwaters entering from the Mekong River during the wet monsoon. Our results suggest that the groundwater-derived dissolved inorganic phosphorus (DIP) contribution to Tonle Sap is more than 30% of the average inflows from all natural sources. Since the productivity of the lake appears to be phosphorus limited, this finding suggests that the role of groundwater is significant for Tonle Sap Lake and perhaps for other flood pulse systems worldwide.

  4. Sap flow measurements to determine the transpiration of facade greenings

    Science.gov (United States)

    Hölscher, Marie-Therese; Nehls, Thomas; Wessolek, Gerd

    2014-05-01

    Facade greening is expected to make a major contribution to the mitigation of the urban heat-island effect through transpiration cooling, thermal insulation and shading of vertical built structures. However, no studies are available on water demand and the transpiration of urban vertical green. Such knowledge is needed as the plants must be sufficiently watered, otherwise the posited positive effects of vertical green can turn into disadvantages when compared to a white wall. Within the framework of the German Research Group DFG FOR 1736 "Urban Climate and Heat Stress" this study aims to test the practicability of the sap flow technique for transpiration measurements of climbing plants and to obtain potential transpiration rates for the most commonly used species. Using sap flow measurements we determined the transpiration of Fallopia baldschuanica, Parthenocissus tricuspidata and Hedera helix in pot experiments (about 1 m high) during the hot summer period from August 17th to August 30th 2012 under indoor conditions. Sap flow measurements corresponded well to simultaneous weight measurement on a daily base (factor 1.19). Fallopia baldschuanica has the highest daily transpiration rate based on leaf area (1.6 mm d-1) and per base area (5.0 mm d-1). Parthenocissus tricuspidata and Hedera helix show transpiration rates of 3.5 and 0.4 mm d-1 (per base area). Through water shortage, transpiration strongly decreased and leaf temperature measured by infrared thermography increased by 1 K compared to a well watered plant. We transferred the technique to outdoor conditions and will present first results for facade greenings in the inner-city of Berlin for the hottest period in summer 2013.

  5. MODEL OF AN ELECTRONIC EDUCATIONAL RESOURCE OF NEW GENERATION

    Directory of Open Access Journals (Sweden)

    Anatoliy V. Loban

    2016-01-01

    Full Text Available The mathematical structure of the modular architecture of an electronic educational resource (EER of new generation, which allows to decompose the process of studying the subjects of the course at a hierarchically ordered set of data (knowledge and procedures for manipulating them, to determine the roles of participants of process of training of and technology the development and use of EOR in the study procrate.

  6. Flux, rejection and fouling during microfiltration and ultrafiltration of sugar palm sap using a pilot plant scale

    Directory of Open Access Journals (Sweden)

    Wanichapichart, P.

    2006-07-01

    Full Text Available The possibility of using a pilot plant scale microfiltration (MF and ultrafiltration (UF to clarify and reduce number of bacteria, yeast and mould of sugar palm sap was studied. The membrane used was multi channel tubular ceramic membrane (ZrO2-TiO2 with membrane pore size 0.2 and 0.1 μm and molecular weight cut off (MWCO 300 and 50 kDa for microfiltration and ultrafiltration respectively. The experiment was carried out to investigate the rejection of the components in sugar palm sap, permeate flux and fouling characteristics. The results showed that the turbidity, the total solid, the viscosity and the numbers of bacteria, yeast and mould in the permeate obtained by MF and UF were reduced significantly compared to those of fresh sugar palm sap. The total soluble solid, total sugar, reducing sugar and pH were not affected by MF and UF. The permeate fluxes for all membranes were reduced greatly as the volume concentration ratio (VCR increased due to severe fouling. The irreversible fouling on membrane surface and/or inside the membrane tended to increase with increasing membrane pore size or MWCO. The result also suggested that protein and small particle in the sugar palm sap were probably responsible for the internal fouling of large pore size membrane. According to the physical, chemical and microorganism quality results, both MF and UF showed the potential use for improving the quality of sugar palm sap but flux reduction due to fouling was a major problem affecting the process performance.

  7. Accounting Control Technology Using SAP: A Case-Based Approach

    Science.gov (United States)

    Ragan, Joseph; Puccio, Christopher; Talisesky, Brandon

    2014-01-01

    The Sarbanes-Oxley Act (SOX) revolutionized the accounting and audit industry. The use of preventative and process controls to evaluate the continuous audit process done via an SAP ERP ECC 6.0 system is key to compliance with SOX and managing costs. This paper can be used in a variety of ways to discuss issues associated with auditing and testing…

  8. Evaluasi dan Rencana Pengembangan Penerapan Aplikasi Enterprise Resource Planning (ERP: Studi Kasus pada PT Astra Graphia

    Directory of Open Access Journals (Sweden)

    Santo Fernandi Wijaya

    2011-12-01

    Full Text Available A firm’s success in bussiness competition can be supported by integrated information systems. A program application based on Enterprise Resource Planning (ERP like SAP is an integrated program that is able to provide business transaction management solutions. This study aims to on the ERP system running at PT Astra Graphia, particularly at relevant departments dealing with income derived at a period of time and costs associated with implementation and application maintenance of SAP (Systems, Applications and Products in Data Processing program. Furthermore, this study aims to give suggestions based on information systems development evaluation results, in terms of business processes, performance, and financial. Analyses were performed using the IT Balanced Scorecard, and the development of information systems used the Accelerated SAP (ASAP in which the results are able to provide suggestions of system development with the first phase of ASAP method namely preparation and the second phase namely blueprint. 

  9. Indiscriminate Fisheries: Understanding the Foodweb of the Great Tonle Sap Lake, Cambodia

    Science.gov (United States)

    Hannah, L.; Kaufman, L.

    2014-12-01

    Indiscriminate fisheries target multiple species with multiple gear types. In contrast to well-studied, industrialized single-species, single-gear fisheries, little theory and little but growing literature on practice exists for indiscriminate fisheries. Indiscriminate fisheries are disproportionately important in low-income countries, providing most of the animal protein intake in countries such as Cambodia and Bangladesh. Indiscriminate fisheries may be either freshwater or marine, but here we focus on what may be the largest freshwater indiscriminate fishery in the world. Cambodia's freshwater fishery stands out because it provides the majority of animal protein to over 3 million people living in poverty. The fishery of the Tonle Sap lake is one of the largest, if not the largest contributor to this freshwater fish take, and is perhaps the largest freshwater fishery in the world. In contrast to its importance, very little is known about the foodweb ecology of this system, or how community management which now governs the entire fishery, interacts with biological and physical factors such as climate change.The foodweb of the Tonle Sap has changed dramatically due to high fishing pressure. A system that once harbored giant catfish, barbs and stingrays is now dominated by fish under 20cm in length. The simplification of the system may not have reduced its productivity. Theory of indiscriminate fisheries suggests that r-selected species may be favored and that biomass available for harvest may be maximized, while being more sensitive to environmental fluctuations such as climate change due to food web simplification. The r-selection and size predictions of theory have been confirmed by observations of the Tonle Sap. Early model results suggest sensitivity to environmental stochasticity. The interaction of these ecological changes with social systems will be tested in the Tonle Sap. Fisheries management across the lake has been transferred to community management

  10. Implantación de SAP en el área financiera de una empresa de adhesivos

    OpenAIRE

    Mateo Pérez, Daniel

    2013-01-01

    El presente proyecto pretende analizar la conveniencia de la implantación del sistema SAP en el departamento de finanzas de la delegación de México de una multinacional especializada en la fabricación y distribución de adhesivos. Inicialmente se revisan las características principales de los sistemas ERP, el fundamento del sistema SAP ERP y una explicación del entorno, incidiendo en las necesidades del área financiera vinculadas a los procesos de producción de adhesivos. Esta información f...

  11. Transport and use of CO2 in the xylem sap of Populus deltoides

    International Nuclear Information System (INIS)

    Stringer, J.W.; Kimmerer, T.W.

    1990-01-01

    Results of recent experiments indicate an internal cycling of respiratory CO 2 in woody plants. The CO 2 concentration of xylem sap expressed from the twigs of field grown Populus deltoides ranged from .14 to .50 mM. The pH of the xylem sap was 5.7 to 6.7, providing a significant bicarbonate concentration in many samples. Total dissolved inorganic carbon (DIC = CO 2 + H 2 CO 3 + HCO 3 - ) was 0.5 mM to 1.3 mM. Results from the analysis of xylem sap of 10 other species of woody plants were similar. To determine the fate of DIC delivered to the leaves of Populus deltoides, excised leaves were fed 1mM NaHCO 3 (2 μCi NaH 14 CO 3 ml -1 ). Less than 0.4% of the label escaped from the leaves, and ≥93% was fixed. Of the carbon fixed 56% of the 14 C was found in the petiole and midrib, and 14% was in the major veins, with the remaining 30% in the minor veins and lamina. Shading of the peptiole and midrib of leaves decreased the amount of fixed carbon in these tissues to 38% and increased the amount in the lamina to 55%

  12. A single-probe heat pulse method for estimating sap velocity in trees.

    Science.gov (United States)

    López-Bernal, Álvaro; Testi, Luca; Villalobos, Francisco J

    2017-10-01

    Available sap flow methods are still far from being simple, cheap and reliable enough to be used beyond very specific research purposes. This study presents and tests a new single-probe heat pulse (SPHP) method for monitoring sap velocity in trees using a single-probe sensor, rather than the multi-probe arrangements used up to now. Based on the fundamental conduction-convection principles of heat transport in sapwood, convective velocity (V h ) is estimated from the temperature increase in the heater after the application of a heat pulse (ΔT). The method was validated against measurements performed with the compensation heat pulse (CHP) technique in field trees of six different species. To do so, a dedicated three-probe sensor capable of simultaneously applying both methods was produced and used. Experimental measurements in the six species showed an excellent agreement between SPHP and CHP outputs for moderate to high flow rates, confirming the applicability of the method. In relation to other sap flow methods, SPHP presents several significant advantages: it requires low power inputs, it uses technically simpler and potentially cheaper instrumentation, the physical damage to the tree is minimal and artefacts caused by incorrect probe spacing and alignment are removed. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

  13. The adaptor molecule signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is essential in mechanisms involving the Fyn tyrosine kinase for induction and progression of collagen-induced arthritis.

    Science.gov (United States)

    Zhong, Ming-Chao; Veillette, André

    2013-11-01

    Signaling lymphocytic activation molecule-associated protein (SAP) is an Src homology 2 domain-only adaptor involved in multiple immune cell functions. It has also been linked to immunodeficiencies and autoimmune diseases, such as systemic lupus erythematosus. Here, we examined the role and mechanism of action of SAP in autoimmunity using a mouse model of autoimmune arthritis, collagen-induced arthritis (CIA). We found that SAP was essential for development of CIA in response to collagen immunization. It was also required for production of collagen-specific antibodies, which play a key role in disease pathogenesis. These effects required SAP expression in T cells, not in B cells. In mice immunized with a high dose of collagen, the activity of SAP was nearly independent of its ability to bind the protein tyrosine kinase Fyn and correlated with the capacity of SAP to promote full differentiation of follicular T helper (TFH) cells. However, with a lower dose of collagen, the role of SAP was more dependent on Fyn binding, suggesting that additional mechanisms other than TFH cell differentiation were involved. Further studies suggested that this might be due to a role of the SAP-Fyn interaction in natural killer T cell development through the ability of SAP-Fyn to promote Vav-1 activation. We also found that removal of SAP expression during progression of CIA attenuated disease severity. However, it had no effect on disease when CIA was clinically established. Together, these results indicate that SAP plays an essential role in CIA because of Fyn-independent and Fyn-dependent effects on TFH cells and, possibly, other T cell types.

  14. Sap flow for beech (Fagus sylvatica L.) in a natural and a managed forest-effect of spatial heterogeneity

    DEFF Research Database (Denmark)

    Dalsgaard, Lise; Mikkelsen, Teis Nørgaard; Bastrup-Birk, Annemarie

    2011-01-01

    -aged 80-year old stand (MAN), with a height of 25 m, and a total of 283 stems ha(-1) with diameters averaging 38 cm. Stem sap flow, J(s) (g m(-2) s(-1)), was continuously measured in 12 (MAN) and 13 (NAT) trees using 20-mm long heat dissipation sensors. Individual tree measures of sap flow were correlated...

  15. Detection of Candida albicans Sap2 in cancer patient serum samples by an indirect competitive enzyme-linked immunosorbent assay for the diagnosis of candidiasis.

    Science.gov (United States)

    Wang, Yicun; Gao, Xiang; Zhi Gang, J U; Liu, Jingyuan; Dong, Shuai; Wang, Li

    2013-01-01

    The secreted aspartyl proteinases 2 (Sap2) of Candida albicans (C. albicans) is a potential marker of candididasis. It is a virulence factor associated with adherence and tissue invasion. In order to detect Sap2 in clinical sera, we developed an indirect competitive enzyme-linked immunosorbent assay (ELISA). Polyclonal antibodies were produced for Sap2 by injecting Sap2 into a New Zealand White inbred rabbit. They could be used at a dilution exceeding 1:1200 in an indirect ELISA, and detected Sap2 concentration up to 1 ng/mL. Of the 286 cancer serum samples tested, 16.8% were found as candidiasis. The test was simple and economical to perform and had a level of sensitivity for detection of low-titer positive sera; thus, it may be proven to be of value in epidemiological studies on candidiasis.

  16. Metabolic Coevolution in the Bacterial Symbiosis of Whiteflies and Related Plant Sap-Feeding Insects.

    Science.gov (United States)

    Luan, Jun-Bo; Chen, Wenbo; Hasegawa, Daniel K; Simmons, Alvin M; Wintermantel, William M; Ling, Kai-Shu; Fei, Zhangjun; Liu, Shu-Sheng; Douglas, Angela E

    2015-09-15

    Genomic decay is a common feature of intracellular bacteria that have entered into symbiosis with plant sap-feeding insects. This study of the whitefly Bemisia tabaci and two bacteria (Portiera aleyrodidarum and Hamiltonella defensa) cohoused in each host cell investigated whether the decay of Portiera metabolism genes is complemented by host and Hamiltonella genes, and compared the metabolic traits of the whitefly symbiosis with other sap-feeding insects (aphids, psyllids, and mealybugs). Parallel genomic and transcriptomic analysis revealed that the host genome contributes multiple metabolic reactions that complement or duplicate Portiera function, and that Hamiltonella may contribute multiple cofactors and one essential amino acid, lysine. Homologs of the Bemisia metabolism genes of insect origin have also been implicated in essential amino acid synthesis in other sap-feeding insect hosts, indicative of parallel coevolution of shared metabolic pathways across multiple symbioses. Further metabolism genes coded in the Bemisia genome are of bacterial origin, but phylogenetically distinct from Portiera, Hamiltonella and horizontally transferred genes identified in other sap-feeding insects. Overall, 75% of the metabolism genes of bacterial origin are functionally unique to one symbiosis, indicating that the evolutionary history of metabolic integration in these symbioses is strongly contingent on the pattern of horizontally acquired genes. Our analysis, further, shows that bacteria with genomic decay enable host acquisition of complex metabolic pathways by multiple independent horizontal gene transfers from exogenous bacteria. Specifically, each horizontally acquired gene can function with other genes in the pathway coded by the symbiont, while facilitating the decay of the symbiont gene coding the same reaction. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  17. 14CO2 labeling: a reliable technique for rapid measurement of total root exudation capacity and vascular sap flow in crops

    International Nuclear Information System (INIS)

    Singh, Bhupinder; Ahuja, Sumedha; Pandey, Renu; Singhal, R.K.

    2014-01-01

    Ability of roots to release organic compounds in its rhizosphere is known to improve plant available nutrients and reduces heavy metal toxicity by immobilization. It is regarded as an important determinant of micro nutrient deficiency tolerance in plants. Uptake of nutrients and translocation of photoassimilates, on the other hand are governed by the strength of the transpiration stream and sink demand respectively. Measurement of vascular sap flow, thus, is critical for understanding of the translocation efficiency and consequently the sink demand that keeps changing during the crop growth cycle. Measurement of the root exudation capacity and the vascular sap flow is cumbersome and time consuming. Since, the exudates released by the roots and the photosynthates translocated between the source and the sink are essentially carbon compounds, use of labeled carbon as tag could potentially be exploited for a rapid and reliable measurement of exudation and vascular sap flow in crop plants. We report here the experimental results involving 14 C labeling of groundnut, a legume crop, as 14 CO 2 generated by acidification of sodium bicarbonate. An additional factor of seed gamma irradiation was used to generate variability in the root exudation and the sap flow. The 14 C release by the roots was compared against the 14 C transport in the vascular sap. An experimental hypothesis that a higher 14 C level in the vascular sap would indicate a higher root release of carbon by the roots into the rhizosphere was verified. (author)

  18. Phytoplasma protein effector SAP11 enhances insect vector reproduction by manipulating plant development and defense hormone biosynthesis.

    Science.gov (United States)

    Sugio, Akiko; Kingdom, Heather N; MacLean, Allyson M; Grieve, Victoria M; Hogenhout, Saskia A

    2011-11-29

    Phytoplasmas are insect-transmitted phytopathogenic bacteria that can alter plant morphology and the longevity and reproduction rates and behavior of their insect vectors. There are various examples of animal and plant parasites that alter the host phenotype to attract insect vectors, but it is unclear how these parasites accomplish this. We hypothesized that phytoplasmas produce effectors that modulate specific targets in their hosts leading to the changes in plant development and insect performance. Previously, we sequenced and mined the genome of Aster Yellows phytoplasma strain Witches' Broom (AY-WB) and identified 56 candidate effectors. Here, we report that the secreted AY-WB protein 11 (SAP11) effector modulates plant defense responses to the advantage of the AY-WB insect vector Macrosteles quadrilineatus. SAP11 binds and destabilizes Arabidopsis CINCINNATA (CIN)-related TEOSINTE BRANCHED1, CYCLOIDEA, PROLIFERATING CELL FACTORS 1 and 2 (TCP) transcription factors, which control plant development and promote the expression of lipoxygenase (LOX) genes involved in jasmonate (JA) synthesis. Both the Arabidopsis SAP11 lines and AY-WB-infected plants produce less JA on wounding. Furthermore, the AY-WB insect vector produces more offspring on AY-WB-infected plants, SAP11 transgenic lines, and plants impaired in CIN-TCP and JA synthesis. Thus, SAP11-mediated destabilization of CIN-TCPs leads to the down-regulation of LOX2 expression and JA synthesis and an increase in M. quadrilineatus progeny. Phytoplasmas are obligate inhabitants of their plant host and insect vectors, in which the latter transmits AY-WB to a diverse range of plant species. This finding demonstrates that pathogen effectors can reach beyond the pathogen-host interface to modulate a third organism in the biological interaction.

  19. Studies on the interactions of SAP-1 (an N-terminal truncated form of cystatin S) with its binding partners by CD-spectroscopic and molecular docking methods.

    Science.gov (United States)

    Yadav, Vikash Kumar; Mandal, Rahul Shubhra; Puniya, Bhanwar Lal; Singh, Sarman; Yadav, Savita

    2015-01-01

    SAP-1 is a 113 amino acid long single-chain protein which belongs to the type 2 cystatin gene family. In our previous study, we have purified SAP-1 from human seminal plasma and observed its cross-class inhibitory property. At this time, we report the interaction of SAP-1 with diverse proteases and its binding partners by CD-spectroscopic and molecular docking methods. The circular dichroism (CD) spectroscopic studies demonstrate that the conformation of SAP-1 is changed after its complexation with proteases, and the alterations in protein secondary structure are quantitatively calculated with increase of α-helices and reduction of β-strand content. To get insight into the interactions between SAP-1 and proteases, we make an effort to model the three-dimensional structure of SAP-1 by molecular modeling and verify its stability and viability through molecular dynamics simulations and finally complexed with different proteases using ClusPro 2.0 Server. A high degree of shape complementarity is examined within the complexes, stabilized by a number of hydrogen bonds (HBs) and hydrophobic interactions. Using HB analyses in different protein complexes, we have identified a series of key residues that may be involved in the interactions between SAP-1 and proteases. These findings will assist to understand the mechanism of inhibition of SAP-1 for different proteases and provide intimation for further research.

  20. Comparison of sap flux, moisture flux tower and MODIS enhanced vegetation index methods for estimating riparian evapotranspiration

    Science.gov (United States)

    Nagler, Pamela L.; Glenn, Edward P.; Morino, Kiyomi; Neale, Christopher M.U; Cosh, Michael H.

    2010-01-01

    Riparian evapotranspiration (ET) was measured on a salt cedar (Tamarix spp.) dominated river terrace on the Lower Colorado River from 2007 to 2009 using tissue-heat-balance sap flux sensors at six sites representing very dense, medium dense, and sparse stands of plants. Salt cedar ET varied markedly across sites, and sap flux sensors showed that plants were subject to various degrees of stress, detected as mid-day depression of transpiration and stomatal conductance. Sap flux results were scaled from the leaf level of measurement to the stand level by measuring plant-specific leaf area index and fractional ground cover at each site. Results were compared to Bowen ratio moisture tower data available for three of the sites. Sap flux sensors and flux tower results ranked the sites the same and had similar estimates of ET. A regression equation, relating measured ET of salt cedar and other riparian plants and crops on the Lower Colorado River to the Enhanced Vegetation Index from the MODIS sensor on the Terra satellite and reference crop ET measured at meteorological stations, was able to predict actual ET with an accuracy or uncertainty of about 20%, despite between-site differences for salt cedar. Peak summer salt cedar ET averaged about 6 mm d-1 across sites and methods of measurement.

  1. THE IMPACT OF ENTERPRISE RESOURCE PLANNING SYSTEMS ON MANAGEMENT ACCOUNTING

    Directory of Open Access Journals (Sweden)

    Andreea Gabriela PONORÎCĂ

    2014-05-01

    Full Text Available The added value on the ongoing improvement process of forecasts for financial and non-financial information systems is the main object of this study during nowadays context. Our results reveal the findings of an empirical research on the communication with various software vendors, such as SAP or Oracle, confirming the hypothesis that enterprise resource planning systems are not so well connected with the field of financial reporting analysis, but strongly linked with the management accounting field. Our study is and will be further opened for future research, passing over the limits of resource planning.

  2. El docente, su entorno y el síndrome de agotamiento profesional (SAP) en colegios públicos en Bogotá(Colombia)

    OpenAIRE

    Gómez-Restrepo, Carlos; Rodríguez, Viviana; Padilla M, Andrea C; Avella-García, Claudia B

    2009-01-01

    Introducción: El síndrome de agotamiento profesional (SAP) o burnout es de gran importancia y prevalencia entre los docentes; no obstante, en Colombia se ha estudiado poco. Objetivos: (1) Describir algunas características de los docentes respecto a su entorno laboral, bienestar y satisfacción personal, difcultades laborales, relación con estudiantes con difcultades y autoconocimiento, y (2) analizar su relación con el SAP en tres colegios públicos de Bogotá. Método: Se evaluó el SAP en docent...

  3. Introduction of Sap ERP System Into a Heterogeneous Academic Community

    Science.gov (United States)

    Mornar, Vedran; Fertalj, Krešimir; Kalpić, Damir

    2010-06-01

    Introduction of a complex ERP system like SAP into a heterogeneous academic environment like the University of Zagreb is far from being a trivial task. The University comprises more than 30 constituents, called faculties or academies, geographically dispersed, with long and specific traditions. Financing according to the lump sum principle, enforced in Croatia as a side effect of the in Europe obligatory and omnipresent Bologna process, requires a unified view on the educational institutions in order to provide a more just and appropriate financing scheme than the current one. After the experience with own development to support educational tasks and student administration, for standard financial and administration tasks SAP has been chosen as the most appropriate platform. The developer was selected after public bidding and the authors' institution was chosen for the pilot project. The authors were playing principal roles in the process of successful deployment and still expect to offer their expertise for implementation in the rest of the University. However, serious risks stemming from lack of motivation by some constituents are present.

  4. Comparison of Matrix Frequency-Doubling Technology (FDT) Perimetry with the SWEDISH Interactive Thresholding Algorithm (SITA) Standard Automated Perimetry (SAP) in Mild Glaucoma.

    Science.gov (United States)

    Doozandeh, Azadeh; Irandoost, Farnoosh; Mirzajani, Ali; Yazdani, Shahin; Pakravan, Mohammad; Esfandiari, Hamed

    2017-01-01

    This study aimed to compare second-generation frequency-doubling technology (FDT) perimetry with standard automated perimetry (SAP) in mild glaucoma. Forty-seven eyes of 47 participants who had mild visual field defect by SAP were included in this study. All participants were examined using SITA 24-2 (SITA-SAP) and matrix 24-2 (Matrix-FDT). The correlations of global indices and the number of defects on pattern deviation (PD) plots were determined. Agreement between two sets regarding the stage of visual field damage was assessed. Pearson's correlation, intra-cluster comparison, paired t-test, and 95% limit of agreement were calculated. Although there was no significant difference between global indices, the agreement between the two devices regarding the global indices was weak (the limit of agreement for mean deviation was -6.08 to 6.08 and that for pattern standard deviation was -4.42 to 3.42). The agreement between SITA-SAP and Matrix-FDT regarding the Glaucoma Hemifield Test (GHT) and the number of defective points in each quadrant and staging of the visual field damage was also weak. Because the correlation between SITA-SAP and Matrix-FDT regarding global indices, GHT, number of defective points, and stage of the visual field damage in mild glaucoma is weak, Matrix-FDT cannot be used interchangeably with SITA-SAP in the early stages of glaucoma.

  5. Use of sap flow measurements to validate stomatal functions for mature beech (Fagus sylvatica) in view of ozone uptake calculations

    International Nuclear Information System (INIS)

    Braun, Sabine; Schindler, Christian; Leuzinger, Sebastian

    2010-01-01

    For a quantitative estimate of the ozone effect on vegetation reliable models for ozone uptake through the stomata are needed. Because of the analogy of ozone uptake and transpiration it is possible to utilize measurements of water loss such as sap flow for quantification of ozone uptake. This technique was applied in three beech (Fagus sylvatica) stands in Switzerland. A canopy conductance was calculated from sap flow velocity and normalized to values between 0 and 1. It represents mainly stomatal conductance as the boundary layer resistance in forests is usually small. Based on this relative conductance, stomatal functions to describe the dependence on light, temperature, vapour pressure deficit and soil moisture were derived using multivariate nonlinear regression. These functions were validated by comparison with conductance values directly estimated from sap flow. The results corroborate the current flux parameterization for beech used in the DO 3 SE model. - A method was developed to derive stomatal functions and ozone uptake calculation from sap flow.

  6. Ultrafiltration and thermal processing effects on Maillard reaction products and biological properties of date palm sap syrups (Phoenix dactylifera L.).

    Science.gov (United States)

    Makhlouf-Gafsi, Ines; Krichen, Fatma; Mansour, Riadh Ben; Mokni, Abir; Sila, Assad; Bougatef, Ali; Blecker, Christophe; Attia, Hamadi; Besbes, Souhail

    2018-08-01

    The effect of ultrafiltration process and temperature concentration on MRPs content and antioxidant, antimicrobial and cytotoxic properties of date palm sap syrups were investigated. MRPs were analyzed by HPLC. Antioxidant activity was evaluated by reducing power and DPPH free radical and H 2 O 2 scavenging activities. Antimicrobial activity was evaluated by the agar disk diffusion method. In vitro cytotoxic activity was examined by cell proliferation assay. Date sap syrups displayed strong antioxidant activities which are correlated 5HMF and 2F contents. In addition, concentration at 100 °C, unlike ultrafiltration process, enhanced significantly the antioxidant activities sap syrups and total phenolic contents. The antimicrobial activities showed marked activity against S. enterica, P. aeruginosa, S. aureus, L. monocytogenes with an inhibition zone of 21, 34, 27 and 34 mm respectively. Cytotoxicity assays showed that sap syrups can inhibit the proliferation of HeLa cell lines at high concentration. Published by Elsevier Ltd.

  7. Data on xylem sap proteins from Mn- and Fe-deficient tomato plants obtained using shotgun proteomics.

    Science.gov (United States)

    Ceballos-Laita, Laura; Gutierrez-Carbonell, Elain; Takahashi, Daisuke; Abadía, Anunciación; Uemura, Matsuo; Abadía, Javier; López-Millán, Ana Flor

    2018-04-01

    This article contains consolidated proteomic data obtained from xylem sap collected from tomato plants grown in Fe- and Mn-sufficient control, as well as Fe-deficient and Mn-deficient conditions. Data presented here cover proteins identified and quantified by shotgun proteomics and Progenesis LC-MS analyses: proteins identified with at least two peptides and showing changes statistically significant (ANOVA; p ≤ 0.05) and above a biologically relevant selected threshold (fold ≥ 2) between treatments are listed. The comparison between Fe-deficient, Mn-deficient and control xylem sap samples using a multivariate statistical data analysis (Principal Component Analysis, PCA) is also included. Data included in this article are discussed in depth in the research article entitled "Effects of Fe and Mn deficiencies on the protein profiles of tomato ( Solanum lycopersicum) xylem sap as revealed by shotgun analyses" [1]. This dataset is made available to support the cited study as well to extend analyses at a later stage.

  8. Detection of Candida albicans Sap2 in cancer patient serum samples by an indirect competitive enzyme-linked immunosorbent assay for the diagnosis of candidiasis

    Directory of Open Access Journals (Sweden)

    Yicun Wang

    2013-01-01

    Full Text Available Background: The secreted aspartyl proteinases 2 (Sap2 of Candida albicans (C. albicans is a potential marker of candididasis. It is a virulence factor associated with adherence and tissue invasion. Aim: In order to detect Sap2 in clinical sera, we developed an indirect competitive enzyme-linked immunosorbent assay (ELISA. Materials and Methods: Polyclonal antibodies were produced for Sap2 by injecting Sap2 into a New Zealand White inbred rabbit. They could be used at a dilution exceeding 1:1200 in an indirect ELISA, and detected Sap2 concentration up to 1 ng/mL. Results: Of the 286 cancer serum samples tested, 16.8% were found as candidiasis. The test was simple and economical to perform and had a level of sensitivity for detection of low-titer positive sera; thus, it may be proven to be of value in epidemiological studies on candidiasis.

  9. The influence of alkalinity of portland cement on the absorption characteristics of superabsorbent polymers (SAP) for use in internally cured concrete

    Science.gov (United States)

    Tabares Tamayo, Juan D.

    The concrete industry increasingly emphasizes advances in novel materials that promote construction of more resilient infrastructure. Due to its potential to improve concrete durability, internal curing (IC) of concrete by means of superabsorbent polymers (SAP) has been identified as one of the most promising technologies of the 21st century. The addition of superabsorbent polymers into a cementitious system promotes further hydration of cement by providing internal moisture during the hardening and strength development periods, and thus limits self-desiccation, shrinkage, and cracking. This thesis presents the work performed on the series of cement pastes with varying alkalinity of their pore solutions to provide a better understanding of: (1) the influence of the chemistry of the pore solution (i.e. its level of alkalinity and the type of ionic species present) on the absorption capacity of SAP, and (2) the effectiveness of SAP with different absorption capacities as an internal curing agent. This research work was divided into three stages: (a) materials characterization, (b) measurement of absorption capacity of SAP in synthetic pore solutions, and (c) evaluation of the internal curing effectiveness of SAP. During the first stage (Materials Characterization), pore solutions were extracted from the fresh (5 minutes old) cement pastes prepared using cements with three different levels of alkalinity. The pH values of the extracted solutions were determined (using the pH meter) and their chemical analysis was performed by means of titration (concentration of hydroxyl), ion chromatography (sulfates and chlorides), atomic absorption (AA) and inductively coupled plasma optical emission spectrometry (ICP) (sodium, potassium and calcium). The commercial SAP adopted for this study was used with "as-supplied" gradation and with the finer gradation obtained by grinding the original polymer in the 6850 Cryomilling Freezer/Mill. The physical properties of these SAP's, such

  10. Optimización de la Gestión de Recursos Humanos (GRH) aplicando las soluciones SAP.

    OpenAIRE

    Arribas Martinez, Montserrat Ana

    2017-01-01

    Transformation of the HR function through technologies such as SAP HCM that facilitates the configuration of shared service centers (centralization) and which favors the digital transformation of their employees. Transformación de la Función de Recursos Humans mediante tecnología SAP HCM que facilita la configuración de centros de servicio compartidos (centralitzación) y que favorece la transformación digital de sus empleados. Transformació de la Funció de Recursos Humans mitjançant tec...

  11. Concrete with superabsorbent polymers (SAP) - experience from the Fehmarn field exposure station in Rødbyhavn

    DEFF Research Database (Denmark)

    Hasholt, Marianne Tange; Pade, Claus

    2011-01-01

    A field exposure station has been established in Rødbyhavn Habour. One of the concrete types tested is with superabsorbent polymer (SAP) - a new type of additive, which can be used to mitigate self-desiccation and to control air void structure. This paper presents results from the extensive...... laboratory test program, which was conducted before test panels were placed in Rødbyhavn Habour. Results show that when using SAP, it is possible to produce concrete with a pre-defined air void structure. Strength and transport properties are comparable to the properties of a reference concrete, but results...

  12. GUIDELINES FOR EVALUATION OF PSYCHOLOGICAL AND PEDAGOGICAL QUALITY CHARACTERISTICS OF ELECTRONIC EDUCATIONAL RESOURCES

    Directory of Open Access Journals (Sweden)

    Galina P. Lavrentieva

    2014-05-01

    Full Text Available The article highlights the causes of insufficient effective use of electronic learning resources and sets out the guidelines on ways to solve the aforementioned problems. The set of didactic, methodical, psychological, pedagogical, design and ergonomic quality requirements is considered for evaluation, selection and application of information and communication technologies in the educational process. The most appropriate mechanisms for the ICT introduction into the learning process are disclosed as it should meet the specific learning needs of the student and the objectives of the educational process. The guidance for psycho-educational assessment of quality of electronic educational resources is provided. It is argued that the effectiveness of the ICT use is to be improved by means of quality evaluation mechanisms involved into the educational process.

  13. Availability, Use and Constraints to Use of Electronic Information Resources by Postgraduates Students at the University of Ibadan

    Directory of Open Access Journals (Sweden)

    Dare Samuel Adeleke

    2017-12-01

    Full Text Available Availability, awareness and use of electronic resources provide access to authoritative, reliable, accurate and timely access to information. The use of electronic information resources (EIRs can enable innovation in teaching and increase timeliness in research of postgraduate students which will eventual result into encouragement of the expected research-led enquiry in this digital age. The study adopted a descriptive survey design. Samples of 300 of postgraduate students within seven out 13 Faculties were randomly selected. Data were collected using questionnaire designed to elicit response from respondents and data were analyzed using descriptive statistics methods percentages, mean, and standard deviation. Results indicated that internet was ranked most available and used in the university. Low level of usage of electronic resources, in particular, full texts data bases is linked to a number of constraints: Interrupted power supply was ranked highest among other factors as speed and capacity of computers, retrieval of records with high recall and low precision, retrieving records relevant to information need, lack of knowledge of search techniques to retrieve information effectively, non possession of requisite IT skills and problems accessing the internet. The study recommended that usage of electronic resources be made compulsory, intensifying awareness campaigns concerning the availability, training on use of electronic resources and the problem of power outage be addressed.

  14. Deciphering complex dynamics of water counteraction around secondary structural elements of allosteric protein complex: Case study of SAP-SLAM system in signal transduction cascade.

    Science.gov (United States)

    Samanta, Sudipta; Mukherjee, Sanchita

    2018-01-28

    The first hydration shell of a protein exhibits heterogeneous behavior owing to several attributes, majorly local polarity and structural flexibility as revealed by solvation dynamics of secondary structural elements. We attempt to recognize the change in complex water counteraction generated due to substantial alteration in flexibility during protein complex formation. The investigation is carried out with the signaling lymphocytic activation molecule (SLAM) family of receptors, expressed by an array of immune cells, and interacting with SLAM-associated protein (SAP), composed of one SH2 domain. All atom molecular dynamics simulations are employed to the aqueous solutions of free SAP and SLAM-peptide bound SAP. We observed that water dynamics around different secondary structural elements became highly affected as well as nicely correlated with the SLAM-peptide induced change in structural rigidity obtained by thermodynamic quantification. A few instances of contradictory dynamic features of water to the change in structural flexibility are explained by means of occluded polar residues by the peptide. For βD, EFloop, and BGloop, both structural flexibility and solvent accessibility of the residues confirm the obvious contribution. Most importantly, we have quantified enhanced restriction in water dynamics around the second Fyn-binding site of the SAP due to SAP-SLAM complexation, even prior to the presence of Fyn. This observation leads to a novel argument that SLAM induced more restricted water molecules could offer more water entropic contribution during the subsequent Fyn binding and provide enhanced stability to the SAP-Fyn complex in the signaling cascade. Finally, SLAM induced water counteraction around the second binding site of the SAP sheds light on the allosteric property of the SAP, which becomes an integral part of the underlying signal transduction mechanism.

  15. Deciphering complex dynamics of water counteraction around secondary structural elements of allosteric protein complex: Case study of SAP-SLAM system in signal transduction cascade

    Science.gov (United States)

    Samanta, Sudipta; Mukherjee, Sanchita

    2018-01-01

    The first hydration shell of a protein exhibits heterogeneous behavior owing to several attributes, majorly local polarity and structural flexibility as revealed by solvation dynamics of secondary structural elements. We attempt to recognize the change in complex water counteraction generated due to substantial alteration in flexibility during protein complex formation. The investigation is carried out with the signaling lymphocytic activation molecule (SLAM) family of receptors, expressed by an array of immune cells, and interacting with SLAM-associated protein (SAP), composed of one SH2 domain. All atom molecular dynamics simulations are employed to the aqueous solutions of free SAP and SLAM-peptide bound SAP. We observed that water dynamics around different secondary structural elements became highly affected as well as nicely correlated with the SLAM-peptide induced change in structural rigidity obtained by thermodynamic quantification. A few instances of contradictory dynamic features of water to the change in structural flexibility are explained by means of occluded polar residues by the peptide. For βD, EFloop, and BGloop, both structural flexibility and solvent accessibility of the residues confirm the obvious contribution. Most importantly, we have quantified enhanced restriction in water dynamics around the second Fyn-binding site of the SAP due to SAP-SLAM complexation, even prior to the presence of Fyn. This observation leads to a novel argument that SLAM induced more restricted water molecules could offer more water entropic contribution during the subsequent Fyn binding and provide enhanced stability to the SAP-Fyn complex in the signaling cascade. Finally, SLAM induced water counteraction around the second binding site of the SAP sheds light on the allosteric property of the SAP, which becomes an integral part of the underlying signal transduction mechanism.

  16. A Study on Developing Evaluation Criteria for Electronic Resources in Evaluation Indicators of Libraries

    Science.gov (United States)

    Noh, Younghee

    2010-01-01

    This study aimed to improve the current state of electronic resource evaluation in libraries. While the use of Web DB, e-book, e-journal, and other e-resources such as CD-ROM, DVD, and micro materials is increasing in libraries, their use is not comprehensively factored into the general evaluation of libraries and may diminish the reliability of…

  17. Nucleotides, micro- and macro-nutrients, limonoids, flavonoids, and hydroxycinnamates composition in the phloem sap of sweet orange

    Science.gov (United States)

    Hijaz, Faraj; Manthey, John A.; Van der Merwe, Deon; Killiny, Nabil

    2016-01-01

    ABSTRACT Currently, the global citrus production is declining due to the spread of Huanglongbing (HLB). HLB, otherwise known as citrus greening, is caused by Candidatus Liberibacter asiaticus (CLas) and is transmitted by the Asian citrus psyllids (ACP), Diaphorina citri Kuwayama. ACP transmits CLas bacterium while feeding on the citrus phloem sap. Multiplication of CLas in the phloem of citrus indicates that the sap contains all the essential nutrients needed for CLas. In this study, we investigated the micro- and macro-nutrients, nucleotides, and others secondary metabolites of phloem sap from pineapple sweet orange. The micro- and macro-nutrients were analyzed using inductively coupled plasma-mass spectroscopy (ICP-MS) and inductively coupled plasma-optical emission spectroscopy (ICP-OES). Nucleotides and other secondary metabolites analysis was accomplished by reversed phase HPLC coupled with UV, fluorescence detection, or negative mode electrospray ionization mass spectrometry (ESI-MS). Calcium (89 mM) was the highest element followed by potassium (38.8 mM) and phosphorous (24 mM). Magnesium and sulfur were also abundant and their concentrations were 15 and 9 mM, respectively. The rest of the elements were found in low amounts (flavonoids. In addition, several hydroxycinnamates were detected. The results of this study will increase our knowledge about the nature and the chemical composition of citrus phloem sap. PMID:27171979

  18. A quantitative analysis of faulty EPCs in the SAP reference model

    NARCIS (Netherlands)

    Mendling, J.; Moser, M.; Neumann, G.; Verbeek, H.M.W.; Dongen, van B.F.; Aalst, van der W.M.P.

    2006-01-01

    The SAP reference model contains more than 600 non-trivial process models expressed in terms of Event-driven Process Chains (EPCs). We have automatically translated these EPCs into YAWL models and analyzed these models usingWofYAWL, a veri¯cation tool based on Petri nets. We discovered that at least

  19. Investigating differences in the root to shoot transfer and xylem sap solubility of organic compounds between zucchini, squash and soybean using a pressure chamber method.

    Science.gov (United States)

    Garvin, Naho; Doucette, William J; White, Jason C

    2015-07-01

    A pressure chamber method was used to examine differences in the root to shoot transfer and xylem sap solubility of caffeine (log Kow=-0.07), triclocarban (log Kow=3.5-4.2) and endosulfan (log Kow=3.8-4.8) for zucchini (cucurbita pepo ssp pepo), squash (cucurbita pepo ssp ovifera), and soybean (glycine max L.). Transpiration stream concentration factors (TSCF) for caffeine (TSCF=0.8) were statistically equivalent for all plant species. However, for the more hydrophobic endosulfan and triclocarban, the TSCF values for zucchini (TSCF=0.6 and 0.4, respectively) were 3 and 10 times greater than the soybean and squash (TSCF=0.2 and 0.05, respectively). The difference in TSCF values was examined by comparing the measured solubilities of caffeine, endosulfan and triclocarban in deionized water to those in soybean and zucchini xylem saps using a modified shake flask method. The measured solubility of organic contaminants in xylem sap has not previously been reported. Caffeine solubilities in the xylem saps of soybean and zucchini were statistically equal to deionized water (21500mgL(-1)) while endosulfan and triclocarban solubilities in the zucchini xylem sap were significantly greater (0.43 and 0.21mgL(-1), respectively) than that of the soybean xylem sap (0.31 and 0.11mgL(-1), respectively) and deionized water (0.34 and 0.11mgL(-1), respectively). This suggests that the enhanced root to shoot transfer of hydrophobic organics reported for zucchini is partly due to increased solubility in the xylem sap. Further xylem sap characterization is needed to determine the mechanism of solubility enhancement. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Effect of ultrafiltration process on physico-chemical, rheological, microstructure and thermal properties of syrups from male and female date palm saps.

    Science.gov (United States)

    Makhlouf-Gafsi, Ines; Baklouti, Samia; Mokni, Abir; Danthine, Sabine; Attia, Hamadi; Blecker, Christophe; Besbes, Souhail; Masmoudi, Manel

    2016-07-15

    This study investigates the effect of the ultrafiltration process on physicochemical, rheological, microstructure and thermal properties of syrups from male and female date palm sap. All the studied syrups switched from pseudoplastic rheological behaviour (n=0.783) to Newtonian behaviour (n∼1) from 10 to 50 °C respectively and present similar thermal profiles. Results revealed that the ultrafiltration process significantly affects the rheological behaviour of the male and female syrups. These differences on rheological properties are attributed to the variation of chemical composition between sap and sap permeate syrups. Furthermore, the effect of temperature on viscosity of the syrups was investigated during heating and cooling processes at the same shear rate (50s(-1)). This study provides idea of the stability of the syrup by evaluating the area between heating and cooling curves. Actually, the syrup prepared from male sap permeate is the most stable between the four studied syrups. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. E-SAP: efficient-strong authentication protocol for healthcare applications using wireless medical sensor networks.

    Science.gov (United States)

    Kumar, Pardeep; Lee, Sang-Gon; Lee, Hoon-Jae

    2012-01-01

    A wireless medical sensor network (WMSN) can sense humans' physiological signs without sacrificing patient comfort and transmit patient vital signs to health professionals' hand-held devices. The patient physiological data are highly sensitive and WMSNs are extremely vulnerable to many attacks. Therefore, it must be ensured that patients' medical signs are not exposed to unauthorized users. Consequently, strong user authentication is the main concern for the success and large scale deployment of WMSNs. In this regard, this paper presents an efficient, strong authentication protocol, named E-SAP, for healthcare application using WMSNs. The proposed E-SAP includes: (1) a two-factor (i.e., password and smartcard) professional authentication; (2) mutual authentication between the professional and the medical sensor; (3) symmetric encryption/decryption for providing message confidentiality; (4) establishment of a secure session key at the end of authentication; and (5) professionals can change their password. Further, the proposed protocol requires three message exchanges between the professional, medical sensor node and gateway node, and achieves efficiency (i.e., low computation and communication cost). Through the formal analysis, security analysis and performance analysis, we demonstrate that E-SAP is more secure against many practical attacks, and allows a tradeoff between the security and the performance cost for healthcare application using WMSNs.

  2. E-SAP: Efficient-Strong Authentication Protocol for Healthcare Applications Using Wireless Medical Sensor Networks

    Directory of Open Access Journals (Sweden)

    Hoon-Jae Lee

    2012-02-01

    Full Text Available A wireless medical sensor network (WMSN can sense humans’ physiological signs without sacrificing patient comfort and transmit patient vital signs to health professionals’ hand-held devices. The patient physiological data are highly sensitive and WMSNs are extremely vulnerable to many attacks. Therefore, it must be ensured that patients’ medical signs are not exposed to unauthorized users. Consequently, strong user authentication is the main concern for the success and large scale deployment of WMSNs. In this regard, this paper presents an efficient, strong authentication protocol, named E-SAP, for healthcare application using WMSNs. The proposed E-SAP includes: (1 a two-factor (i.e., password and smartcard professional authentication; (2 mutual authentication between the professional and the medical sensor; (3 symmetric encryption/decryption for providing message confidentiality; (4 establishment of a secure session key at the end of authentication; and (5 professionals can change their password. Further, the proposed protocol requires three message exchanges between the professional, medical sensor node and gateway node, and achieves efficiency (i.e., low computation and communication cost. Through the formal analysis, security analysis and performance analysis, we demonstrate that E-SAP is more secure against many practical attacks, and allows a tradeoff between the security and the performance cost for healthcare application using WMSNs.

  3. Assessing dam development, land use conversion, and climate change pressures on tributary river flows and water quality of the Mekong's Tonle Sap basin.

    Science.gov (United States)

    Cochrane, T. A.; Arias, M. E.; Oeurng, C.; Arnaiz, M.; Piman, T.

    2016-12-01

    The Tonle Sap Lake is Southeast Asia's most productive freshwater fishery, but the productivity of this valuable ecosystem is under threat from extensive development in the lower Mekong. With dams potentially blocking all major tributaries along the lower Mekong River, the role of local Tonle Sap basin tributaries for maintaining environmental flows, sediment loads, and fish recruitment is becoming increasingly critical. Development within the Tonle Sap basin, however, is not stagnant. Developers are proposing extensive dam development in key Tonle Sap tributaries (see Figure). Some dams will provide hydroelectricity and others will provide opportunities for large-scale irrigation resulting in agro-industrial expansion. There is thus an immediate need to assess the current situation and understand future effects of dam development and land use conversion under climate change on local riverine ecosystems. A combination of remote sensing, field visits, and hydro-meteorological data analyses enabled an assessment of water infrastructure and agricultural development in the basin. The application of SWAT for modelling flows and water quality combined with HEC-RESSIM for reservoir operations enabled for a holistic modelling approach. Initial results show that dams and land use change dominate flow and water quality responses, when compared to climate change. Large ongoing dam and irrigation development in the Pursat and Battambang subbasins will critically alter the natural river flows to the Tonle Sap Lake. Some of the observed dams did not have provisions for sediment flushing, clearing of flooded areas, fish passages, or other environmental protection measures. Poor planning and operation of this infrastructure could have dire consequences on the fragile riverine ecosystem of Tonle Sap tributaries, resulting in fish migration barriers, losses in aquatic habitats, and ecological degradation. The seemingly chaotic development in the Tonle Sap basin induces a great level

  4. The Social Construction Of Systems Applications Products (SAP R/3 By Employees Of A South African Chemical Industries Company

    Directory of Open Access Journals (Sweden)

    Arnold Beyleveld

    2005-11-01

    Full Text Available Many companies that have implemented an Enterprise Resource Planning (ERP system do not reap the intended benefits of the potential inherent in these systems despite their exorbitant implementation cost. The reasons for this are numerous. This study is aimed at understanding the social impact a Systems Applications Products (SAP R/3 implementation had on the end users of a South African Company in the Chemical Industry. A qualitative process evaluation study was undertaken to obtain a clearer understanding of the underlying organisational cultural factors that emerged from such an implementation. The objective was to provide a framework for companies considering such an implementation to ensure better system productivity and to assist companies already using an ERP solution with continuous improvement.

  5. THE MODEL OF LINGUISTIC TEACHERS’ COMPETENCY DEVELOPMENT ON DESIGNING MULTIMEDIA ELECTRONIC EDUCATIONAL RESOURCES IN THE MOODLE SYSTEM

    OpenAIRE

    Anton M. Avramchuk

    2017-01-01

    The article is devoted to the problem of developing the competency of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system. The concept of "the competence of teachers of language disciplines on designing multimedia electronic educational resources in the Moodle system" is justified and defined. Identified and characterized the components by which the levels of the competency development of teachers of language disciplines on designing ...

  6. Exploring the Potential of Banana SAP as Dye for the Adinkra ...

    African Journals Online (AJOL)

    A study was carried out to explore the potential of banana sap as a dye for the Adinkra industry in Ghana. Pseudostem extract of banana and stem bark extract of Bridelia micratha were compared as dyeing stuff. A consumer preference study was also conducted to assess the acceptability of the products developed.

  7. Accuracy of a composite score using daily SAPS II and LOD scores for predicting hospital mortality in ICU patients hospitalized for more than 72 h.

    Science.gov (United States)

    Timsit, J F; Fosse, J P; Troché, G; De Lassence, A; Alberti, C; Garrouste-Orgeas, M; Azoulay, E; Chevret, S; Moine, P; Cohen, Y

    2001-06-01

    In most databases used to build general severity scores the median duration of intensive care unit (ICU) stay is less than 3 days. Consequently, these scores are not the most appropriate tools for measuring prognosis in studies dealing with ICU patients hospitalized for more than 72 h. To develop a new prognostic model based on a general severity score (SAPS II), an organ dysfunction score (LOD) and evolution of both scores during the first 3 days of ICU stay. Prospective multicenter study. Twenty-eight intensive care units (ICUs) in France. A training data-set was created with four ICUs during an 18-month period (893 patients). Seventy percent of the patients were medical (628) aged 66 years. The median SAPS II was 38. The ICU and hospital mortality rates were 22.7% and 30%, respectively. Forty-seven percent (420 patients) were transferred from hospital wards. In this population, the calibration (Hosmer-Lemeshow chi-square: 37.4, P = 0.001) and the discrimination [area under the ROC curves: 0.744 (95 % CI: 0.714-0.773)] of the original SAPS II were relatively poor. A validation data set was created with a random panel of 24 French ICUs during March 1999 (312 patients). The LOD and SAPS II scores were calculated during the first (SAPS1, LOD1), second (SAPS2, LOD2), and third (SAPS3, LOD3) calendar days. The LOD and SAPS scores alterations were assigned the value "1" when scores increased with time and "0" otherwise. A multivariable logistic regression model was used to select variables measured during the first three calendar days, and independently associated with death. Selected variables were: SAPS II at admission [OR: 1.04 (95 % CI: 1.027-1.053) per point], LOD [OR: 1.16 (95 % CI: 1.085-1.253) per point], transfer from ward [OR: 1.74 (95 % CI: 1.25-2.42)], as well as SAPS3-SAPS2 alterations [OR: 1.516 (95 % CI: 1.04-2.22)], and LOD3-LOD2 alterations [OR: 2.00 (95 % CI: 1.29-3.11)]. The final model has good calibration and discrimination properties in the

  8. Effect of strain rate and temperature at high strains on fatigue behavior of SAP alloys

    DEFF Research Database (Denmark)

    Blucher, J.T.; Knudsen, Per; Grant, N.J.

    1968-01-01

    Fatigue behavior of three SAP alloys of two nominal compositions (7 and 13% Al2O3) was studied in terms of strain rate and temperature at high strains; strain rate had no effect on life at 80 F, but had increasingly greater effect with increasing temperature above 500 F; life decreased with decre......Fatigue behavior of three SAP alloys of two nominal compositions (7 and 13% Al2O3) was studied in terms of strain rate and temperature at high strains; strain rate had no effect on life at 80 F, but had increasingly greater effect with increasing temperature above 500 F; life decreased...

  9. Determining the level of awareness of the physicians in using the variety of electronic information resources and the effecting factors.

    Science.gov (United States)

    Papi, Ahmad; Ghazavi, Roghayeh; Moradi, Salimeh

    2015-01-01

    Understanding of the medical society's from the types of information resources for quick and easy access to information is an imperative task in medical researches and management of the treatment. The present study was aimed to determine the level of awareness of the physicians in using various electronic information resources and the factors affecting it. This study was a descriptive survey. The data collection tool was a researcher-made questionnaire. The study population included all the physicians and specialty physicians of the teaching hospitals affiliated to Isfahan University of Medical Sciences and numbered 350. The sample size based on Morgan's formula was set at 180. The content validity of the tool was confirmed by the library and information professionals and the reliability was 95%. Descriptive statistics were used including the SPSS software version 19. On reviewing the need of the physicians to obtain the information on several occasions, the need for information in conducting the researches was reported by the maximum number of physicians (91.9%) and the usage of information resources, especially the electronic resources, formed 65.4% as the highest rate with regard to meeting the information needs of the physicians. Among the electronic information databases, the maximum awareness was related to Medline with 86.5%. Among the various electronic information resources, the highest awareness (43.3%) was related to the E-journals. The highest usage (36%) was also from the same source. The studied physicians considered the most effective deterrent in the use of electronic information resources as being too busy and lack of time. Despite the importance of electronic information resources for the physician's community, there was no comprehensive knowledge of these resources. This can lead to less usage of these resources. Therefore, careful planning is necessary in the hospital libraries in order to introduce the facilities and full capabilities of the

  10. Management of setpoint information using SAP-PM; Gerenciamento das informacoes de setpoints usando o SAP-PM

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Robison Tirre; Pereira, Paulo Manoel Borges [TBG - Transportadora Brasileira Gasoduto Bolivia Brasil S.A., Rio de Janeiro, RJ (Brazil)

    2005-07-01

    It is always a challenge to assure that the set points of field instruments and valves (e.g., transmitters, regulator valves, shut off valves, safety valves, etc) are adjusted in conformity either to the originally designed values or the ones established by the operations team, specially when multiple teams are involved in the activity. In such circumstances, keeping these values updated on proper data sheets is also a defying task. The correct information is essential to the Control Room operators and its accuracy is a step ahead towards operational availability and safety. TBG, through CMMS (Computerized Maintenance Management System) - SAP R/3, PM Module, developed a set of automated tools to integrate data from different environments (reports, handhelds, workflows and procedures), thus allowing allow a better control over the set point adjustment process. (author)

  11. Managing Selection for Electronic Resources: Kent State University Develops a New System to Automate Selection

    Science.gov (United States)

    Downey, Kay

    2012-01-01

    Kent State University has developed a centralized system that manages the communication and work related to the review and selection of commercially available electronic resources. It is an automated system that tracks the review process, provides selectors with price and trial information, and compiles reviewers' feedback about the resource. It…

  12. Are phloem-derived amino acids the origin of the elevated malate concentration in the xylem sap following mineral N starvation in soybean?

    Science.gov (United States)

    Vitor, Simone C; do Amarante, Luciano; Sodek, Ladaslav

    2018-05-16

    A substantial increase in malate in the xylem sap of soybean subjected to mineral N starvation originates mainly from aspartate, a prominent amino acid of the phloem. A substantial increase in xylem malate was found when non-nodulated soybean plants were transferred to a N-free medium. Nodulated plants growing in the absence of mineral N and, therefore, dependent on symbiotic N 2 fixation also contained elevated concentrations of malate in the xylem sap. When either nitrate or ammonium was supplied, malate concentrations in the xylem sap were low, both for nodulated and non-nodulated plants. Evidence was obtained that the elevated malate concentration of the xylem was derived from amino acids supplied by the phloem. Aspartate was a prominent component of the phloem sap amino acids and, therefore, a potential source of malate. Supplying the roots of intact plants with 13 C-aspartate revealed that malate of the xylem sap was readily labelled under N starvation. A hypothetical scheme is proposed whereby aspartate supplied by the phloem is metabolised in the roots and the products of this metabolism cycled back to the shoot. Under N starvation, aspartate metabolism is diverted from asparagine synthesis to supply N for the synthesis of other amino acids via transaminase activity. The by-product of aspartate transaminase activity, oxaloacetate, is transformed to malate and its export accounts for much of the elevated concentration of malate found in the xylem sap. This mechanism represents a new additional role for malate during mineral N starvation of soybean, beyond that of charge balance.

  13. Estandarización de un método espectrofluorométrico para medición de proteasa aspártica secretada (Sap de Candida albicans

    Directory of Open Access Journals (Sweden)

    Luz Stella Ramírez Aristizábal

    Full Text Available Introducción: la proteasa aspártica secretada (Sap es considerada un factor de virulencia en el proceso de infección por Candida albicans. La frecuencia de candidiasis a nivel mundial aumenta cada día, razón por la cual se hace necesario encontrar nuevos medicamentos que combatan esta enfermedad, al mismo tiempo desarrollar métodos que evalúen en forma rápida compuestos inhibidores de Sap. Objetivo: estandarizar un método fluorescente para identificar la inhibición de actividad de Sap. Métodos: se indujo la producción de Sap en cultivos de C. albicans según la metodología descrita por Capobiancoy se evaluaron sus niveles por electroforesis en geles SDS-PAGE en diferentes lapsos de tiempos. La actividad de Sap fue verificada por espectrofluorometría, para lo cual se determinaron las condiciones de reacción, variando las concentraciones de cobre y fluorexon, y los resultados de inhibición, se expresaron como disminución en la señal de fluorescencia. Como control de inhibición de Sap se utilizó Pepstatin A y como control positivo de actividad proteasa se utilizó pancreatina. Resultados: se establecieron concentraciones de 5,5 y 5,0 µM para fluorexon y cobre respectivamente; el tiempo óptimo de acoplamiento de estos fue de 120 min y la mayor actividad de Sap se alcanzó a las 22 h de incubación. Conclusiones: las condiciones estandarizadas para el método espectrofluorométrico, permiten confirmar la inhibición de Sap por Pepstatin A y demostrar que es un método viable para evaluar inhibidores de esta proteasa.

  14. Converting positive and negative symptom scores between PANSS and SAPS/SANS.

    Science.gov (United States)

    van Erp, Theo G M; Preda, Adrian; Nguyen, Dana; Faziola, Lawrence; Turner, Jessica; Bustillo, Juan; Belger, Aysenil; Lim, Kelvin O; McEwen, Sarah; Voyvodic, James; Mathalon, Daniel H; Ford, Judith; Potkin, Steven G; Fbirn

    2014-01-01

    The Scale for the Assessment of Positive Symptoms (SAPS), the Scale for the Assessment of Negative Symptoms (SANS), and the Positive and Negative Syndrome Scale for Schizophrenia (PANSS) are the most widely used schizophrenia symptom rating scales, but despite their co-existence for 25 years no easily usable between-scale conversion mechanism exists. The aim of this study was to provide equations for between-scale symptom rating conversions. Two-hundred-and-five schizophrenia patients [mean age±SD=39.5±11.6, 156 males] were assessed with the SANS, SAPS, and PANSS. Pearson's correlations between symptom scores from each of the scales were computed. Linear regression analyses, on data from 176 randomly selected patients, were performed to derive equations for converting ratings between the scales. Intraclass correlations, on data from the remaining 29 patients, not part of the regression analyses, were performed to determine rating conversion accuracy. Between-scale positive and negative symptom ratings were highly correlated. Intraclass correlations between the original positive and negative symptom ratings and those obtained via conversion of alternative ratings using the conversion equations were moderate to high (ICCs=0.65 to 0.91). Regression-based equations may be useful for conversion between schizophrenia symptom severity as measured by the SANS/SAPS and PANSS, though additional validation is warranted. This study's conversion equations, implemented at http:/converteasy.org, may aid in the comparison of medication efficacy studies, in meta- and mega-analyses examining symptoms as moderator variables, and in retrospective combination of symptom data in multi-center data sharing projects that need to pool symptom rating data when such data are obtained using different scales. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. End-of-life resource recovery from emerging electronic products

    DEFF Research Database (Denmark)

    Parajuly, Keshav; Habib, Komal; Cimpan, Ciprian

    2016-01-01

    Integrating product design with appropriate end-of-life (EoL) processing is widely recognized to have huge potentials in improving resource recovery from electronic products. In this study, we investigate both the product characteristics and EoL processing of robotic vacuum cleaner (RVC), as a case...... of emerging electronic product, in order to understand the recovery fate of different materials and its linkage to product design. Ten different brands of RVC were dismantled and their material composition and design profiles were studied. Another 125 RVCs (349 kg) were used for an experimental trial...... at a conventional ‘shred-and-separate’ type preprocessing plant in Denmark. A detailed material flow analysis was performed throughout the recycling chain. The results show a mismatch between product design and EoL processing, and the lack of practical implementation of ‘Design for EoL’ thinking. In the best...

  16. 14CO2 labeling. A reliable technique for rapid measurement of total root exudation capacity and vascular sap flow in crop plants

    International Nuclear Information System (INIS)

    Bhupinder Singh; Sumedha Ahuja; Renu Pandey; Singhal, R.K.

    2014-01-01

    Root release of organic compounds and rate of the vascular sap flow are important for understanding the nutrient and the source-sink dynamics in plants, however, their determination is procedurally cumbersome and time consuming. We report here a simple method involving 14 C labeling for rapid and reliable measurement of root exudates and vascular sap flow rate in a variable groundnut population developed through seed gamma irradiation using a cobalt source ( 60 Co). An experimental hypothesis that a higher 14 C level in the vascular sap would indicate a higher root release of carbon by the roots into the rhizosphere was verified. (author)

  17. A comparison of serum amyloid A (SAA) synthesis with that of the pentraxins: Serum amyloid P (SAP) and C-reactive protein (CRP)

    International Nuclear Information System (INIS)

    Tatsuta, E.; Shirahama, T.; Sipe, J.D.; Skinner, M.

    1986-01-01

    Serum amyloid A (SAA) and serum amyloid P (SAP) were detected in cultures of hepatocytes which had been isolated from normal CBA/J mice by the collagenase perfusion technique. SAP production in 24 h cultures was more resistant than SAA and total protein synthesis to inhibition by actinomycin D, but was more sensitive to inhibition by 48 h. However, the production of SAP was more sensitive to cycloheximide than SAA and total protein throughout the 48 hr incubation period. SAP and SAA levels in the culture media were suppressed by treatment of liver cells with 10 -6 M of colchicine for 48 h. Inhibition of SAP production by colchicine was the same regardless of culture condition, but the effect of colchicine on SAA synthesis varied according to the presence of serum of monokine. These observations also support the concept that the two amyloid proteins are produced under different regulatory mechanisms. When C-reactive protein (CRP) was not detected in the sera of patients with severe chronic liver diseases, the SAA levels were very low. When CRP was detected, SAA values were within the normal range. Thus, in order to produce SAA, liver cells in these patients not only were viable but also maintained their specialized function

  18. Sourcing strategies to keep up with competition: the case of SAP

    Directory of Open Access Journals (Sweden)

    Michelle Antero

    2014-01-01

    Full Text Available This paper applies the Red Queen theory to explain how organizations utilize various sourcing arrangements in order to compete in an evolutionary arms race where only the strongest competitors will survive. The case study incorporates competition, and views sourcing strategies as a means to improve the firm’s viability to survive competition in the marketplace. The study begins by positioning the Red Queen theory within the sourcing literature. It subsequently applies the framework to a case study of SAP AG to illustrate how sourcing strategies have changed over time in response to the logic of competition. The case study reveals that (a organizations are adaptive systems and capable of learning to make strategic changes pertaining to sourcing arrangements; (b organizations select the terms on which they want to compete by developing certain capabilities within the firm; (c organizations are reflexive and over time develop competitive hysteresis which allows them to become stronger competitors. In the case of SAP AG, various sourcing arrangements were selected over its 40-year history to respond to technological and market changes.

  19. Use of electronic sales data to tailor nutrition education resources for an ethnically diverse population.

    Science.gov (United States)

    Eyles, H; Rodgers, A; Ni Mhurchu, C

    2010-02-01

    Nutrition education may be most effective when personally tailored. Individualised electronic supermarket sales data offer opportunities to tailor nutrition education using shopper's usual food purchases. The present study aimed to use individualised electronic supermarket sales data to tailor nutrition resources for an ethnically diverse population in a large supermarket intervention trial in New Zealand. Culturally appropriate nutrition education resources (i.e. messages and shopping lists) were developed with the target population (through two sets of focus groups) and ethnic researchers. A nutrient database of supermarket products was developed using retrospective sales data and linked to participant sales to allow tailoring by usual food purchases. Modified Heart Foundation Tick criteria were used to identify 'healthier' products in the database suitable for promotion in the resources. Rules were developed to create a monthly report listing the tailored and culturally targeted messages to be sent to each participant, and to produce automated, tailored shopping lists. Culturally targeted nutrition messages (n = 864) and shopping lists (n = 3 formats) were developed. The food and nutrient database (n = 3000 top-selling products) was created using 12 months of retrospective sales data, and comprised 60%'healthier' products. Three months of baseline sales data were used to determine usual food purchases. Tailored resources were successfully mailed to 123 Māori, 52 Pacific and 346 non-Māori non-Pacific participants over the 6-month trial intervention period. Electronic supermarket sales data can be used to tailor nutrition education resources for a large number of ethnically diverse supermarket shoppers.

  20. Why size matters: the interactive influences of tree diameter distribution and sap flow parameters on upscaled transpiration.

    Science.gov (United States)

    Berry, Z Carter; Looker, Nathaniel; Holwerda, Friso; Gómez Aguilar, León Rodrigo; Ortiz Colin, Perla; González Martínez, Teresa; Asbjornsen, Heidi

    2018-02-01

    In stands with a broad range of diameters, a small number of very large trees can disproportionately influence stand basal area and transpiration (Et). Sap flow-based Et estimates may be particularly sensitive to large trees due to nonlinear relationships between tree-level water use (Q) and tree diameter at breast height (DBH). Because Q is typically predicted on the basis of DBH and sap flow rates measured in a subset of trees and then summed to obtain Et, we assessed the relative importance of DBH and sap flow variables (sap velocity, Vs, and sapwood depth, Rs) in determining the magnitude of Et and its dependence on large trees in a tropical montane forest ecosystem. Specifically, we developed a data-driven simulation framework to vary the relationship between DBH and Vs and stand DBH distribution and then calculate Q, Et and the proportion of Et contributed by the largest tree in each stand. Our results demonstrate that variation in how Rs is determined in the largest trees can alter estimates up to 26% of Et while variation in how Vs is determined can vary results by up to 132%. Taken together, these results highlight a great need to expand our understanding of water transport in large trees as this hinders our ability to predict water fluxes accurately from stand to catchment scales. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  1. Availability, Level of Use and Constraints to Use of Electronic Resources by Law Lecturers in Public Universities in Nigeria

    Science.gov (United States)

    Amusa, Oyintola Isiaka; Atinmo, Morayo

    2016-01-01

    (Purpose) This study surveyed the level of availability, use and constraints to use of electronic resources among law lecturers in Nigeria. (Methodology) Five hundred and fifty-two law lecturers were surveyed and four hundred and forty-two responded. (Results) Data analysis revealed that the level of availability of electronic resources for the…

  2. De-chlorination and solidification of radioactive LiCl waste salt by using SiO_2-Al_2O_3-P_2O_5 (SAP) inorganic composite including B_2O_3 component

    International Nuclear Information System (INIS)

    Lee, Ki Rak; Park, Hwan-Seo; Cho, In-Hak; Choi, Jung-Hoon; Eun, Hee-Chul; Lee, Tae-Kyo; Han, Seung Youb; Ahn, Do-Hee

    2017-01-01

    SAP (SiO_2-Al_2O_3-P_2O_5) composite has been recently studied in KAERI to deal with the immobilization of radioactive salt waste, one of the most problematic wastes in the pyro-chemical process. Highly unstable salt waste was successfully converted into stable compounds by the dechlorination process with SAPs, and then a durable waste form with a high waste loading was produced when adding glassy materials to dechlorination product. In the present study, U-SAP composite which is SAP bearing glassy component (Boron) was synthesized to remove the adding and mixing steps of glassy materials for a monolithic wasteform. With U-SAPs prepared by a sol-gel process, a series of wasteforms were fabricated to identify a proper reaction condition. Physical and chemical properties of dechlorination products and U-SAP wasteforms were characterized by XRD, DSC, SEM, TGA and PCT-A. A U-SAP wasteform showed suitable properties as a radioactive wasteform such as dense surface morphology, high waste loading, and high durability at the optimized U-SAP/salt ratio 2.

  3. A systematic review of portable electronic technology for health education in resource-limited settings.

    Science.gov (United States)

    McHenry, Megan S; Fischer, Lydia J; Chun, Yeona; Vreeman, Rachel C

    2017-08-01

    The objective of this study is to conduct a systematic review of the literature of how portable electronic technologies with offline functionality are perceived and used to provide health education in resource-limited settings. Three reviewers evaluated articles and performed a bibliography search to identify studies describing health education delivered by portable electronic device with offline functionality in low- or middle-income countries. Data extracted included: study population; study design and type of analysis; type of technology used; method of use; setting of technology use; impact on caregivers, patients, or overall health outcomes; and reported limitations. Searches yielded 5514 unique titles. Out of 75 critically reviewed full-text articles, 10 met inclusion criteria. Study locations included Botswana, Peru, Kenya, Thailand, Nigeria, India, Ghana, and Tanzania. Topics addressed included: development of healthcare worker training modules, clinical decision support tools, patient education tools, perceptions and usability of portable electronic technology, and comparisons of technologies and/or mobile applications. Studies primarily looked at the assessment of developed educational modules on trainee health knowledge, perceptions and usability of technology, and comparisons of technologies. Overall, studies reported positive results for portable electronic device-based health education, frequently reporting increased provider/patient knowledge, improved patient outcomes in both quality of care and management, increased provider comfort level with technology, and an environment characterized by increased levels of technology-based, informal learning situations. Negative assessments included high investment costs, lack of technical support, and fear of device theft. While the research is limited, portable electronic educational resources present promising avenues to increase access to effective health education in resource-limited settings, contingent

  4. Interactive ion-mediated sap flow regulation in olive and laurel stems: physicochemical characteristics of water transport via the pit structure.

    Science.gov (United States)

    Ryu, Jeongeun; Ahn, Sungsook; Kim, Seung-Gon; Kim, TaeJoo; Lee, Sang Joon

    2014-01-01

    Sap water is distributed and utilized through xylem conduits, which are vascular networks of inert pipes important for plant survival. Interestingly, plants can actively regulate water transport using ion-mediated responses and adapt to environmental changes. However, ionic effects on active water transport in vascular plants remain unclear. In this report, the interactive ionic effects on sap transport were systematically investigated for the first time by visualizing the uptake process of ionic solutions of different ion compositions (K+/Ca2+) using synchrotron X-ray and neutron imaging techniques. Ionic solutions with lower K+/Ca2+ ratios induced an increased sap flow rate in stems of Olea europaea L. and Laurus nobilis L. The different ascent rates of ionic solutions depending on K+/Ca2+ ratios at a fixed total concentration increases our understanding of ion-responsiveness in plants from a physicochemical standpoint. Based on these results, effective structural changes in the pit membrane were observed using varying ionic ratios of K+/Ca2+. The formation of electrostatically induced hydrodynamic layers and the ion-responsiveness of hydrogel structures based on Hofmeister series increase our understanding of the mechanism of ion-mediated sap flow control in plants.

  5. An experimental study on Sodalite and SAP matrices for immobilization of spent chloride salt waste

    Science.gov (United States)

    Giacobbo, Francesca; Da Ros, Mirko; Macerata, Elena; Mariani, Mario; Giola, Marco; De Angelis, Giorgio; Capone, Mauro; Fedeli, Carlo

    2018-02-01

    In the frame of Generation IV reactors a renewed interest in pyro-processing of spent nuclear fuel is underway. Molten chloride salt waste arising from the recovering of uranium and plutonium through pyro-processing is one of the problematic wastes for direct application of vitrification or ceramization. In this work, Sodalite and SAP have been evaluated and compared as potential matrices for confinement of spent chloride salt waste coming from pyro-processing. To this aim Sodalite and SAP were synthesized both in pure form and mixed with different glass matrices, i.e. commercially available glass frit and borosilicate glass. The confining matrices were loaded with mixed chloride salts to study their retention capacities with respect to the elements of interest. The matrices were characterized and leached for contact times up to 150 days at room temperature and at 90 °C. SEM analyses were also performed in order to compare the matrix surface before and after leaching. Leaching results are discussed and compared in terms of normalized releases with similar results reported in literature. According to this comparative study the SAP matrix with glass frit binder resulted in the best matrix among the ones studied, with respect to retention capacities for both matrix and spent fuel elements.

  6. SAGES: a suite of freely-available software tools for electronic disease surveillance in resource-limited settings.

    Directory of Open Access Journals (Sweden)

    Sheri L Lewis

    Full Text Available Public health surveillance is undergoing a revolution driven by advances in the field of information technology. Many countries have experienced vast improvements in the collection, ingestion, analysis, visualization, and dissemination of public health data. Resource-limited countries have lagged behind due to challenges in information technology infrastructure, public health resources, and the costs of proprietary software. The Suite for Automated Global Electronic bioSurveillance (SAGES is a collection of modular, flexible, freely-available software tools for electronic disease surveillance in resource-limited settings. One or more SAGES tools may be used in concert with existing surveillance applications or the SAGES tools may be used en masse for an end-to-end biosurveillance capability. This flexibility allows for the development of an inexpensive, customized, and sustainable disease surveillance system. The ability to rapidly assess anomalous disease activity may lead to more efficient use of limited resources and better compliance with World Health Organization International Health Regulations.

  7. Use and Cost of Electronic Resources in Central Library of Ferdowsi University Based on E-metrics

    Directory of Open Access Journals (Sweden)

    Mohammad Reza Davarpanah

    2012-07-01

    Full Text Available The purpose of this study was to investigate the usage of electronic journals in Ferdowsi University, Iran based on e-metrics. The paper also aimed to emphasize the analysis of cost-benefit and the correlation between the journal impact factors and the usage data. In this study experiences of Ferdowsi University library on licensing and usage of electronic resources was evaluated by providing a cost-benefit analysis based on the cost and usage statistics of electronic resources. Vendor-provided data were also compared with local usage data. The usage data were collected by tracking web-based access locally, and by collecting vender-provided usage data. The data sources were one-year of vendor-supplied e-resource usage data such as Ebsco, Elsevier, Proquest, Emerald, Oxford and Springer and local usage data collected from the Ferdowsi university web server. The study found that actual usage values differ for vendor-provided data and local usage data. Elsevier has got the highest usage degree in searches, sessions and downloads. Statistics also showed that a small number of journals satisfy significant amount of use while the majority of journals were used less frequent and some were never used at all. The users preferred the PDF rather than HTML format. The data in subject profile suggested that the provided e-resources were best suited to certain subjects. There was no correlation between IF and electronic journal use. Monitoring the usage of e-resources gained increasing importance for acquisition policy and budget decisions. The article provided information about local metrics for the six surveyed vendors/publishers, e.g. usage trends, requests per package, cost per use as related to the scientific specialty of the university.

  8. Synapse associated protein 102 (SAP102 binds the C-terminal part of the scaffolding protein neurobeachin.

    Directory of Open Access Journals (Sweden)

    Juliane Lauks

    Full Text Available Neurobeachin (Nbea is a multidomain scaffold protein abundant in the brain, where it is highly expressed during development. Nbea-null mice have severe defects in neuromuscular synaptic transmission resulting in lethal paralysis of the newborns. Recently, it became clear that Nbea is important also for the functioning of central synapses, where it is suggested to play a role in trafficking membrane proteins to both, the pre- and post-synaptic sites. So far, only few binding partners of Nbea have been found and the precise mechanism of their trafficking remains unclear. Here, we used mass spectrometry to identify SAP102, a MAGUK protein implicated in trafficking of the ionotropic glutamate AMPA- and NMDA-type receptors during synaptogenesis, as a novel Nbea interacting protein in mouse brain. Experiments in heterologous cells confirmed this interaction and revealed that SAP102 binds to the C-terminal part of Nbea that contains the DUF, PH, BEACH and WD40 domains. Furthermore, we discovered that introducing a mutation in Nbea's PH domain, which disrupts its interaction with the BEACH domain, abolishes this binding, thereby creating an excellent starting point to further investigate Nbea-SAP102 function in the central nervous system.

  9. Building and Managing Electronic Resources in Digital Era in India with Special Reference to IUCAA and NIV, Pune: A Comparative Case Study

    Science.gov (United States)

    Sahu, H. K.; Singh, S. N.

    2015-04-01

    This paper discusses and presents a comparative case study of two libraries in Pune, India, Inter-University Centre for Astronomy and Astrophysics and Information Centre and Library of National Institute of Virology (Indian Council of Medical Research). It compares how both libraries have managed their e-resource collections, including acquisitions, subscriptions, and consortia arrangements, while also developing a collection of their own resources, including pre-prints and publications, video lectures, and other materials in an institutional repository. This study illustrates how difficult it is to manage electronic resources in a developing country like India, even though electronic resources are used more than print resources. Electronic resource management can be daunting, but with a systematic approach, various problems can be solved, and use of the materials will be enhanced.

  10. Comparison of different tree sap flow up-scaling procedures using Monte-Carlo simulations

    Science.gov (United States)

    Tatarinov, Fyodor; Preisler, Yakir; Roahtyn, Shani; Yakir, Dan

    2015-04-01

    An important task in determining forest ecosystem water balance is the estimation of stand transpiration, allowing separating evapotranspiration into transpiration and soil evaporation. This can be based on up-scaling measurements of sap flow in representative trees (SF), which can be done by different mathematical algorithms. The aim of the present study was to evaluate the error associated with different up-scaling algorithms under different conditions. Other types of errors (such as, measurement error, within tree SF variability, choice of sample plot etc.) were not considered here. A set of simulation experiments using Monte-Carlo technique was carried out and three up-scaling procedures were tested. (1) Multiplying mean stand sap flux density based on unit sapwood cross-section area (SFD) by total sapwood area (Klein et al, 2014); (2) deriving of linear dependence of tree sap flow on tree DBH and calculating SFstand using predicted SF by DBH classes and stand DBH distribution (Cermak et al., 2004); (3) same as method 2 but using non-linear dependency. Simulations were performed under different SFD(DBH) slope (bs, positive, negative, zero); different DBH and SFD standard deviations (Δd and Δs, respectively) and DBH class size. It was assumed that all trees in a unit area are measured and the total SF of all trees in the experimental plot was taken as the reference SFstand value. Under negative bs all models tend to overestimate SFstand and the error increases exponentially with decreasing bs. Under bs >0 all models tend to underestimate SFstand, but the error is much smaller than for bs

  11. Chick Hairy1 protein interacts with Sap18, a component of the Sin3/HDAC transcriptional repressor complex

    Directory of Open Access Journals (Sweden)

    Andrade Raquel P

    2007-07-01

    Full Text Available Abstract Background The vertebrate adult axial skeleton, trunk and limb skeletal muscles and dermis of the back all arise from early embryonic structures called somites. Somites are symmetrically positioned flanking the embryo axial structures (neural tube and notochord and are periodically formed in a anterior-posterior direction from the presomitic mesoderm. The time required to form a somite pair is constant and species-specific. This extraordinary periodicity is proposed to depend on an underlying somitogenesis molecular clock, firstly evidenced by the cyclic expression of the chick hairy1 gene in the unsegmented presomitic mesoderm with a 90 min periodicity, corresponding to the time required to form a somite pair in the chick embryo. The number of hairy1 oscillations at any given moment is proposed to provide the cell with both temporal and positional information along the embryo's anterior-posterior axis. Nevertheless, how this is accomplished and what biological processes are involved is still unknown. Aiming at understanding the molecular events triggered by the somitogenesis clock Hairy1 protein, we have employed the yeast two-hybrid system to identify Hairy1 interaction partners. Results Sap18, an adaptor molecule of the Sin3/HDAC transcriptional repressor complex, was found to interact with the C-terminal portion of the Hairy1 protein in a yeast two-hybrid assay and the Hairy1/Sap18 interaction was independently confirmed by co-immunoprecipitation experiments. We have characterized the expression patterns of both sap18 and sin3a genes during chick embryo development, using in situ hybridization experiments. We found that both sap18 and sin3a expression patterns co-localize in vivo with hairy1 expression domains in chick rostral presomitic mesoderm and caudal region of somites. Conclusion Hairy1 belongs to the hairy-enhancer-of-split family of transcriptional repressor proteins. Our results indicate that during chick somitogenesis

  12. Cost of Maple Sap Production for Various Size Tubing Operations

    Science.gov (United States)

    Niel K. Huyler

    2000-01-01

    Reports sap production costs for small (500 to 1,000 taps), medium (1,000 to 5,000), and large (5,000 to 15,000) maple syrup operations that use plastic tubing with vacuum pumping. The average annual operating cost per tap ranged from $4.64 for a 500-tap sugarbush operation to $1.84 for a sugarbush with 10,000 taps. The weighted average was $2.87 per tap or $11.48 per...

  13. Impact of LbSapSal Vaccine in Canine Immunological and Parasitological Features before and after Leishmania chagasi-Challenge.

    Directory of Open Access Journals (Sweden)

    Lucilene Aparecida Resende

    Full Text Available Dogs represent the most important domestic reservoir of L. chagasi (syn. L. infantum. A vaccine against canine visceral leishmaniasis (CVL would be an important tool for decreasing the anxiety related to possible L. chagasi infection and for controlling human visceral leishmaniasis (VL. Because the sand fly salivary proteins are potent immunogens obligatorily co-deposited during transmission of Leishmania parasites, their inclusion in an anti-Leishmania vaccine has been investigated in past decades. We investigated the immunogenicity of the "LbSapSal" vaccine (L. braziliensis antigens, saponin as adjuvant, and Lutzomyia longipalpis salivary gland extract in dogs at baseline (T0, during the post-vaccination protocol (T3rd and after early (T90 and late (T885 times following L. chagasi-challenge. Our major data indicated that immunization with "LbSapSal" is able to induce biomarkers characterized by enhanced amounts of type I (tumor necrosis factor [TNF]-α, interleukin [IL]-12, interferon [IFN]-γ cytokines and reduction in type II cytokines (IL-4 and TGF-β, even after experimental challenge. The establishment of a prominent pro-inflammatory immune response after "LbSapSal" immunization supported the increased levels of nitric oxide production, favoring a reduction in spleen parasitism (78.9% and indicating long-lasting protection against L. chagasi infection. In conclusion, these results confirmed the hypothesis that the "LbSapSal" vaccination is a potential tool to control the Leishmania chagasi infection.

  14. A comparison of daily water use estimates derived from constant-heat sap-flow probe values and gravimetric measurements in pot-grown saplings.

    Science.gov (United States)

    K.A. McCulloh; K. Winter; F.C. Meinzer; M. Garcia; J. Aranda; Lachenbruch B.

    2007-01-01

    The use of Granier-style heat dissipation sensors to measure sap flow is common in plant physiology, ecology, and hydrology. There has been concern that any change to the original Granier design invalidates the empirical relationship between sap flux density and the temperature difference between the probes. We compared daily water use estimates from gravimetric...

  15. Clinical flow cytometric screening of SAP and XIAP expression accurately identifies patients with SH2D1A and XIAP/BIRC4 mutations.

    Science.gov (United States)

    Gifford, Carrie E; Weingartner, Elizabeth; Villanueva, Joyce; Johnson, Judith; Zhang, Kejian; Filipovich, Alexandra H; Bleesing, Jack J; Marsh, Rebecca A

    2014-07-01

    X-linked lymphoproliferative disease is caused by mutations in two genes, SH2D1A and XIAP/BIRC4. Flow cytometric methods have been developed to detect the gene products, SAP and XIAP. However, there is no literature describing the accuracy of flow cytometric screening performed in a clinical lab setting. We reviewed the clinical flow cytometric testing results for 656 SAP and 586 XIAP samples tested during a 3-year period. Genetic testing was clinically performed as directed by the managing physician in 137 SAP (21%) and 115 XIAP (20%) samples. We included these samples for analyses of flow cytometric test accuracy. SH2D1A mutations were detected in 15/137 samples. SAP expression was low in 13/15 (sensitivity 87%, CI 61-97%). Of the 122 samples with normal sequencing, SAP was normal in 109 (specificity 89%, CI 82-94%). The positive predictive values (PPVs) and the negative predictive values (NPVs) were 50% and 98%, respectively. XIAP/BIRC4 mutations were detected in 19/115 samples. XIAP expression was low in 18/19 (sensitivity 95%, CI 73-100%). Of the 96 samples with normal sequencing, 59 had normal XIAP expression (specificity 61%, CI 51-71%). The PPVs and NPVs were 33% and 98%, respectively. Receiver-operating characteristic analysis was able to improve the specificity to 75%. Clinical flow cytometric screening tests for SAP and XIAP deficiencies offer good sensitivity and specificity for detecting genetic mutations, and are characterized by high NPVs. We recommend these tests for patients suspected of having X-linked lymphoproliferative disease type 1 (XLP1) or XLP2. © 2014 Clinical Cytometry Society.

  16. Validation of SAPS3 admission score and its customization for use in Korean intensive care unit patients: a prospective multicentre study.

    Science.gov (United States)

    Lim, So Yeon; Koh, Shin Ok; Jeon, Kyeongman; Na, Sungwon; Lim, Chae-Man; Choi, Won-Il; Lee, Young-Joo; Kim, Seok Chan; Chon, Gyu Rak; Kim, Je Hyeong; Kim, Jae Yeol; Lim, Jaemin; Rhee, Chin Kook; Park, Sunghoon; Kim, Ho Cheol; Lee, Jin Hwa; Lee, Ji Hyun; Park, Jisook; Koh, Younsuck; Suh, Gee Young

    2013-08-01

    To externally validate the simplified acute physiology score 3 (SAPS3) and to customize it for use in Korean intensive care unit (ICU) patients. This is a prospective multicentre cohort study involving 22 ICUs from 15 centres throughout Korea. The study population comprised patients who were consecutively admitted to participating ICUs from 1 July 2010 to 31 January 2011. A total of 4617 patients were enrolled. ICU mortality was 14.3%, and hospital mortality was 20.6%. The patients were randomly assigned into one of two cohorts: a development (n = 2309) or validation (n = 2308) cohort. In the development cohort, the general SAPS3 had good discrimination (area under the receiver operating characteristics curve = 0.829), but poor calibration (Hosmer-Lemeshow goodness-of-fit test H = 123.06, P Customization was achieved by altering the logit of the original SAPS3 equation. The new equation for Korean ICU patients was validated in the validation cohort, and demonstrated both good discrimination (area under the receiver operating characteristics curve = 0.835) and good calibration (H = 4.61, P = 0.799, C = 5.67, P = 0.684). General and regional Australasia SAPS3 admission scores showed poor calibration for use in Korean ICU patients, but the prognostic power of the SAPS3 was significantly improved by customization. Prediction models should be customized before being used to predict mortality in different regions of the world. © 2013 The Authors. Respirology © 2013 Asian Pacific Society of Respirology.

  17. Vapor Pressure Deficit and Sap Velocity Dynamic Coupling in Canopy Dominant Trees in the Amazon basin

    Science.gov (United States)

    Chambers, J. Q.; Gimenez, B.; Jardine, K.; Negron Juarez, R. I.; Cobello, L. O.; Fontes, C.; Dawson, T. E.; Higuchi, N.

    2017-12-01

    In order to improve our ability to predict terrestrial water fluxes, an understanding of the interactions between plant physiology and environmental conditions is necessary, especially in tropical forests which recycle large fluxes of water to the atmosphere. This need has become more relevant due to observed records in global temperature. In this study we show a strong temporal correlation between sap velocity and leaf-to-air vapor pressure deficit (VPD) in canopy dominant trees in two primary rainforest sites in the Amazon basin (Santarém and Manaus, Brazil). As VPDs in the upper canopy (20-30 m) varied throughout the day and night, basal sap velocity (1.5 m) responded rapidly without an observable delay (< 15 min). Sap velocity showed a sigmoidal dependence on VPDs including an exponential increase, an inflection point, and a plateau, in all observed trees. Moreover, a clear diurnal hysteresis in sap velocity, stomatal conductance, and leaf water potential was evident with morning periods showing higher sensitivities to VPD than afternoon and night periods. Diurnal leaf gas exchange observations revealed a morning to midday peak in stomatal conductance, but midday to afternoon peak in transpiration and VPD. Thus, our study confirms that the temporal lag between the Gs peak and VPD peak are the major regulators of the hysteresis phenomenon as previously described by other studies. Moreover, out study provide direct evidence for the role of decreased stomatal conductance in the warm afternoon periods to reduce transpiration and allow for the partial recovery of leaf water potential to less negative values. Our results suggests the possibility of predicting evapotranspiration fluxes from ecosystem to regional scales using remote sensing of vegetation temperature from, for example, thermal images of satellites and drones.

  18. The effect of different trap height on the diversity of sap beetle (Coleoptera: Nitidulidae)

    Science.gov (United States)

    Rahim, Nor Atikah Abdul; Yaakop, Salmah

    2018-04-01

    This paper aim to measure the diversity and abundance of sap beetles in oil palm plantation in Malaysia on different heights, 1.5m and 2.5m above ground. A total 0f 20 baited traps were set up in Felda Lui Muda, Negeri Sembilan and located along three transects. The sap beetles collected weekly for a month and identified until species level and the diversity indexes were measured using Evenness Index (E), Shannon-Wiener Index (H'), Simpson's Index (D') and Margalef's Index (R'). All the diversity indexes indicated that the diversity on the lower height above the ground is higher than the upper height The result also shows that there are significant difference (p<0.05) when tested with t-test between the numbers of individuals on the different trap height although the number of species shows different results.

  19. SAP-like ultrafine-grained Al composites dispersion strengthened with nanometric AlN

    International Nuclear Information System (INIS)

    Balog, M.; Krizik, P.; Yan, M.; Simancik, F.; Schaffer, G.B.; Qian, M.

    2013-01-01

    This paper reports the development of novel Sinter-Aluminum-Pulver (SAP)-like Al–AlN nanocomposites via replacing the native Al 2 O 3 thin films on fine Al powder with a large volume fraction of in situ formed nanometric AlN dispersoids. Fine gas-atomized Al powder (d 50 =1.3 µm) compacts were first partially nitrided at 590 °C in flowing nitrogen, controlled by a small addition of Sn (0.3–0.4 wt%), and subsequently consolidated by hot direct extrusion. The resulting Al–AlN composites consisted of submicrometric Al grains reinforced with nanometric AlN dispersoids together with some nanometric Al 2 O 3 dispersoids. An Al–13 vol% AlN nanocomposite fabricated this way achieved exceptional ultimate tensile strength of 227 MPa, yield strength of 195 MPa and Young's modulus of 66 GPa at 300 °C, superior to typical SAP materials and coarse grained Al–AlN composites. In addition, the Al–13 vol% AlN nanocomposite exhibited good thermal stability up to 500 °C. The strengthening mechanism is discussed

  20. Use of the bleeding sap for investigation of radionuclide transfer to crops through root and translocation of the nuclide in the crops

    International Nuclear Information System (INIS)

    Uchida, Shigeo; Sumiya, Misako; Yanagisawa, Kei; Ohmomo, Yoichiro.

    1991-01-01

    Adsorption and translocation characteristics of radionuclides in the root of tomato plant were investigated. Mature tomato plant was transplanted to culture solution containing 85 Sr, 137 Cs, 131 I, 54 Mn, 60 Co and 65 Zn. Immediately after transplantation, the tomato plant was cut at 10 cm above the surface of the culture solution in order to collect bleeding sap solution (Experiment-1). Another mature tomato plant was cultured for 3 days in culture solution containing radionuclides as mentioned above and then transplanted to fresh culture solution. Bleeding sap solution was also collected in the same way as shown in Experiment-1 (Experiment-2). Activity ratios of bleeding sap to culture solution were measured for several hours. Adsorption and removement of those radionuclides in tomato plant were summarized as follows; 137 Cs was taken up by the root almost at the same speed as that of water and accumulated in the lowest among the six nuclides used in the experiments. The concentrations of 85 Sr, 54 Mn and 65 Zn in the bleeding sap of 3 days' uptake experiment were higher than the initial concentrations of the culture solution for several hours even after the tomato plant was transplanted to fresh culture solution. 131 I and 60 Co were accumulated much in the root and found extremely low in the bleeding sap during the experiment, suggesting that the nuclide were absorbed on the surface of the roots and scarcely moved. (author)

  1. [Use of internet and electronic resources among Spanish intensivist physicians. First national survey].

    Science.gov (United States)

    Gómez-Tello, V; Latour-Pérez, J; Añón Elizalde, J M; Palencia-Herrejón, E; Díaz-Alersi, R; De Lucas-García, N

    2006-01-01

    Estimate knowledge and use habits of different electronic resources in a sample of Spanish intensivists: Internet, E-mail, distribution lists, and use of portable electronic devices. Self-applied questionnaire. A 50-question questionnaire was distributed among Spanish intensivists through the hospital marketing delegates of a pharmaceutical company and of electronic forums. A total of 682 questionnaires were analyzed (participation: 74%). Ninety six percent of those surveyed used Internet individually: 67% admitted training gap. Internet was the second source of clinical consultations most used (61%), slightly behind consultation to colleagues (65%). The pages consulted most were bibliographic databases (65%) and electronic professional journals (63%), with limited use of Evidence Based Medicine pages (19%). Ninety percent of those surveyed used e-mail regularly in the practice of their profession, although 25% admitted that were not aware of its possibilities. The use of E-mail decreased significantly with increase in age. A total of 62% of the intensivists used distribution lists. Of the rest, 42% were not aware of its existence and 32% admitted they had insufficient training to handle them. Twenty percent of those surveyed had portable electronic devices and 64% considered it useful, basically due to its rapid consultation at bedside. Female gender was a negative predictive factor of its use (OR 0.35; 95% CI 0.2-0.63; p=0.0002). A large majority of the Spanish intensivists use Internet and E-mail. E-mail lists and use of portable devices are still underused resources. There are important gaps in training and infrequent use of essential pages. There are specific groups that require directed educational policies.

  2. Model of e-learning with electronic educational resources of new generation

    OpenAIRE

    A. V. Loban; D. A. Lovtsov

    2017-01-01

    Purpose of the article: improving of scientific and methodical base of the theory of the е-learning of variability. Methods used: conceptual and logical modeling of the е-learning of variability process with electronic educational resource of new generation and system analysis of the interconnection of the studied subject area, methods, didactics approaches and information and communication technologies means. Results: the formalization complex model of the е-learning of variability with elec...

  3. SAP aitas Politsei- ja Piirivalveameti finantstöötajate arvu vähendada ligi kolm korda

    Index Scriptorium Estoniae

    2010-01-01

    Politsei- ja Piirivalveamet võttis kasutusele SAP tarkvara, mis on võimeline muutma asutuse finantsjuhtimise, personali-, palgaarvestuse ja logistika valdkondade tööprotsessid efektiivsemaks ja automatiseeritumaks

  4. The amino acid distribution in rachis xylem sap and phloem exudate of Vitis vinifera 'Cabernet Sauvignon' bunches.

    Science.gov (United States)

    Gourieroux, Aude M; Holzapfel, Bruno P; Scollary, Geoffrey R; McCully, Margaret E; Canny, Martin J; Rogiers, Suzy Y

    2016-08-01

    Amino acids are essential to grape berry and seed development and they are transferred to the reproductive structures through the phloem and xylem from various locations within the plant. The diurnal and seasonal dynamics of xylem and phloem amino acid composition in the leaf petiole and bunch rachis of field-grown Cabernet Sauvignon are described to better understand the critical periods for amino acid import into the berry. Xylem sap was extracted by the centrifugation of excised leaf petioles and rachises, while phloem exudate was collected by immersing these structures in an ethylenediaminetetraacetic acid (EDTA) buffer. Glutamine and glutamic acid were the predominant amino acids in the xylem sap of both grapevine rachises and petioles, while arginine and glycine were the principal amino acids of the phloem exudate. The amino acid concentrations within the xylem sap and phloem exudate derived from these structures were greatest during anthesis and fruit set, and a second peak occurred within the rachis phloem at the onset of ripening. The concentrations of the amino acids within the phloem and xylem sap of the rachis were highest just prior to or after midnight while the flow of sugar through the rachis phloem was greatest during the early afternoon. Sugar exudation rates from the rachis was greater than that of the petiole phloem between anthesis and berry maturity. In summary, amino acid and sugar delivery through the vasculature to grape berries fluctuates over the course of the day as well as through the season and is not necessarily related to levels near the source. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  5. Impact of Knowledge Resources Linked to an Electronic Health Record on Frequency of Unnecessary Tests and Treatments

    Science.gov (United States)

    Goodman, Kenneth; Grad, Roland; Pluye, Pierre; Nowacki, Amy; Hickner, John

    2012-01-01

    Introduction: Electronic knowledge resources have the potential to rapidly provide answers to clinicians' questions. We sought to determine clinicians' reasons for searching these resources, the rate of finding relevant information, and the perceived clinical impact of the information they retrieved. Methods: We asked general internists, family…

  6. Xylem sap nitrogen compounds of some Crotalaria species

    Directory of Open Access Journals (Sweden)

    Vitória Angela Pierre

    1999-01-01

    Full Text Available Thirteen species of Crotalaria were analysed for nitrogen compounds in the xylem root bleeding sap. Amino acids were the main form of organic nitrogen found, but only traces of ureides were present. Of the four species analysed for amino acid composition, asparagine was found to be the major amino acid, accounting for over 68% of the nitrogen transported. No striking deviations from this general pattern was found between species, between vegetative and floral stages of development, or between nodulated and non-nodulated plants. It was concluded that the Crotalaria species studied here have an asparagine-based nitrogen metabolism, consistent with many other non-ureide-producing legume species.

  7. Electronic Document Management: A Human Resource Management Case Study

    Directory of Open Access Journals (Sweden)

    Thomas Groenewald

    2004-11-01

    Full Text Available This case study serve as exemplar regarding what can go wrong with the implementation of an electronic document management system. Knowledge agility and knowledge as capital, is outlined against the backdrop of the information society and knowledge economy. The importance of electronic document management and control is sketched thereafter. The literature review is concluded with the impact of human resource management on knowledge agility, which includes references to the learning organisation and complexity theory. The intervention methodology, comprising three phases, follows next. The results of the three phases are presented thereafter. Partial success has been achieved with improving the human efficacy of electronic document management, however the client opted to discontinue the system in use. Opsomming Die gevalle studie dien as voorbeeld van wat kan verkeerd loop met die implementering van ’n elektroniese dokumentbestuur sisteem. Teen die agtergrond van die inligtingsgemeenskap en kennishuishouding word kennissoepelheid en kennis as kapitaal bespreek. Die literatuurstudie word afgesluit met die inpak van menslikehulpbronbestuur op kennissoepelheid, wat ook die verwysings na die leerorganisasie en kompleksietydsteorie insluit. Die metodologie van die intervensie, wat uit drie fases bestaan, volg daarna. Die resultate van die drie fases word vervolgens aangebied. Slegs gedeelte welslae is behaal met die verbetering van die menslike doeltreffendheid ten opsigte van elektroniese dokumentbestuur. Die klient besluit egter om nie voort te gaan om die huidige sisteem te gebruik nie.

  8. Native human serum amyloid P component is a single pentamer

    DEFF Research Database (Denmark)

    Sørensen, Inge Juul; Andersen, Ove; Nielsen, EH

    1995-01-01

    Serum amyloid P component (SAP) and C-reactive protein (CRP) are members of the pentraxin protein family. SAP is the precursor protein to amyloid P component present in all forms of amyloidosis. The prevailing notion is that SAP in circulation has the form of a double pentameric molecule (decamer...... by rocket immunoelectrophoresis and electron microscopy. Thus, electron micrographs of purified SAP showed a predominance of decamers. However, the decamer form of SAP reversed to single pentamers when purified SAP was incorporated into SAP-depleted serum....

  9. SAP is required for the development of innate phenotype in H2-M3-restricted CD8+ T cells1

    Science.gov (United States)

    Bediako, Yaw; Bian, Yao; Zhang, Hong; Cho, Hoonsik; Stein, Paul L.; Wang, Chyung-Ru

    2012-01-01

    H2-M3-restricted T cells have a pre-activated surface phenotype, rapidly expand and produce cytokines upon stimulation and as such, are classified as innate T cells. Unlike most innate T cells, M3-restricted T cells also express CD8αβ co-receptors and a diverse TCR repertoire: hallmarks of conventional MHC Ia-restricted CD8+ T cells. Although iNKT cells are also innate lymphocytes, they are selected exclusively on hematopoietic cells (HC), while M3-restricted T cells can be selected on either hematopoietic or thymic epithelial cells (TEC). Moreover, their phenotypes differ depending on what cells mediate their selection. Though there is a clear correlation between selection on HC and development of innate phenotype, the underlying mechanism remains unclear. SAP is required for the development of iNKT cells and mediates signals from SLAM receptors that are exclusively expressed on HC. Based on their dual selection pathway, M3-restricted T cells present a unique model for studying the development of innate T cell phenotype. Using both polyclonal and transgenic mouse models we demonstrate that while M3-restricted T cells are capable of developing in the absence of SAP, SAP is required for HC-mediated selection, development of pre-activated phenotype and heightened effector functions of M3-restricted T cells. These findings are significant because they directly demonstrate the need for SAP in HC-mediated acquisition of innate T cell phenotype and suggest that due to their SAP-dependent HC-mediated selection, M3-restricted T cells develop a pre-activated phenotype and an intrinsic ability to proliferate faster upon stimulation, allowing for an important role in the early response to infection. PMID:23041566

  10. Antioxidant activity, inhibition of nitric oxide overproduction, and in vitro antiproliferative effect of maple sap and syrup from Acer saccharum.

    Science.gov (United States)

    Legault, Jean; Girard-Lalancette, Karl; Grenon, Carole; Dussault, Catherine; Pichette, André

    2010-04-01

    Antioxidant activity, inhibition of nitric oxide (NO) overproduction, and antiproliferative effect of ethyl acetate extracts of maple sap and syrup from 30 producers were evaluated in regard to the period of harvest in three different regions of Québec, Canada. Oxygen radical absorbance capacity (ORAC) values of maple sap and syrup extracts are, respectively, 12 +/- 6 and 15 +/- 5 micromol of Trolox equivalents (TE)/mg. The antioxidant activity was also confirmed by a cell-based assay. The period of harvest has no statistically significant incidence on the antioxidant activity of both extracts. The antioxidant activity of pure maple syrup was also determined using the ORAC assay. Results indicate that the ORAC value of pure maple syrup (8 +/- 2 micromol of TE/mL) is lower than the ORAC value of blueberry juice (24 +/- 1 micromol of TE/mL) but comparable to the ORAC values of strawberry (10.7 +/- 0.4 micromol of TE/mL) and orange (10.8 +/- 0.5 micromol of TE/mL) juices. Maple sap and syrup extracts showed to significantly inhibit lipopolysaccharide-induced NO overproduction in RAW264.7 murine macrophages. Maple syrup extract was significantly more active than maple sap extract, suggesting that the transformation of maple sap into syrup increases NO inhibition activity. The highest NO inhibition induced by the maple syrup extracts was observed at the end of the season. Moreover, darker maple syrup was found to be more active than clear maple syrup, suggesting that some colored oxidized compounds could be responsible in part for the activity. Finally, maple syrup extracts (50% inhibitory concentration = 42 +/- 6 microg/mL) and pure maple syrup possess a selective in vitro antiproliferative activity against cancer cells.

  11. Root Hydraulics and Root Sap Flow in a Panamanian Low-Land Tropical Forest

    Science.gov (United States)

    Bretfeld, M.; Ewers, B. E.; Hall, J. S.; Ogden, F. L.; Beverly, D.; Speckman, H. N.

    2017-12-01

    In the tropics, trees are subjected to increasingly frequent and severe droughts driven by climate change. Given the hydrological benefits associated with tropical forests, such as reduced peak runoff during high precipitation events and increased base flow during drought periods ("sponge-effect"), the underlying plant-hydrological processes at the soil-plant interface have become the focus of recent research efforts. In Panama, the 2015/16 El Niño-Southern Oscillation (ENSO) event ranks amongst the driest and hottest periods on record, thus providing an excellent opportunity to study the effects of drought on tropical forests. Starting in 2015, we instrumented 76 trees with heat-ratio sap flow sensors in regrowing secondary forest (8-, 25-, and 80-year old stands) in the 15 km2 Agua Salud study area, located in central Panama. Of those trees, 16 individuals were instrumented with additional sap flow sensors on three roots each. Data were logged every 30 minutes and soil moisture was measured at 10, 30, 50, and 100 cm depth. Meteorological data were taken from a nearby met-station. Rooting depth and root density were assessed in eight 2×2×2 m soil pits. In April 2017, we measured hydraulic conductance and vulnerability to cavitation of eight species using the centrifuge technique. Trees in 8-year old forest limited transpiration during the drought whereas no such limitation was evident in trees of the 80-year old forest. Root sap flow data show seasonal shifts in water uptake between individual roots of a given tree, with sap flow decreasing in some roots while simultaneously increasing in other roots during the wet-dry season transition. Roots followed a typical log distribution along the profile, with overall root densities of 46, 43, and 52 roots m-2 in the 8-, 25-, and 80-yo stand, respectively. Roots were found up to 200 cm depth in all forests, with roots >5 cm occurring at lower depths (>125 cm) only in 25- and 80-year old forests. Maximum hydraulic

  12. SAP R/3 plant maintenance making it work for your business

    CERN Document Server

    Stengl, Britta

    2001-01-01

    SAP R/3 Plant Maintenance offers a clear introduction to this small but sophisticated component and provides a highly practical guide to implementing PM. Beginning with a examination of the key business processes underlying PM functionality, the book goes on to cover all the crucial aspects of maintenance planning and execution in R/3. Particular attention is given to integrating plant maintenance with a company's natural process flow.

  13. Challenges in the implementation of an electronic surveillance system in a resource-limited setting: Alerta, in Peru

    Directory of Open Access Journals (Sweden)

    Soto Giselle

    2008-11-01

    Full Text Available Abstract Background Infectious disease surveillance is a primary public health function in resource-limited settings. In 2003, an electronic disease surveillance system (Alerta was established in the Peruvian Navy with support from the U.S. Naval Medical Research Center Detachment (NMRCD. Many challenges arose during the implementation process, and a variety of solutions were applied. The purpose of this paper is to identify and discuss these issues. Methods This is a retrospective description of the Alerta implementation. After a thoughtful evaluation according to the Centers for Disease Control and Prevention (CDC guidelines, the main challenges to implementation were identified and solutions were devised in the context of a resource-limited setting, Peru. Results After four years of operation, we have identified a number of challenges in implementing and operating this electronic disease surveillance system. These can be divided into the following categories: (1 issues with personnel and stakeholders; (2 issues with resources in a developing setting; (3 issues with processes involved in the collection of data and operation of the system; and (4 issues with organization at the central hub. Some of the challenges are unique to resource-limited settings, but many are applicable for any surveillance system. For each of these challenges, we developed feasible solutions that are discussed. Conclusion There are many challenges to overcome when implementing an electronic disease surveillance system, not only related to technology issues. A comprehensive approach is required for success, including: technical support, personnel management, effective training, and cultural sensitivity in order to assure the effective deployment of an electronic disease surveillance system.

  14. 49 CFR Appendix E to Part 40 - SAP Equivalency Requirements for Certification Organizations

    Science.gov (United States)

    2010-10-01

    ... TRANSPORTATION WORKPLACE DRUG AND ALCOHOL TESTING PROGRAMS Pt. 40, App. E Appendix E to Part 40—SAP Equivalency... requirement. The test must accurately measure the application of the knowledge, skills, and abilities... information is being accepted by the certifying agency. 9. Code of Ethics: Certified counselors must pledge to...

  15. Holocene evolution of the Tonle Sap Lake: valley network infill and rates of sedimentation in Cambodia's Great Lake

    Science.gov (United States)

    Best, J.; Darby, S. E.; Langdon, P. G.; Hackney, C. R.; Leyland, J.; Parsons, D. R.; Aalto, R. E.; Marti, M.

    2017-12-01

    Tonle Sap Lake, the largest freshwater lake in SE Asia (c. 120km long and 35 km wide), is a vital ecosystem that provides 40-60% of the protein for the population of Cambodia. The lake is fed by flow from the Mekong River that causes the lake rise in level by c. 8m during monsoonal and cyclone-related floods, with drainage of the lake following the monsoon. Hydropower dam construction on the Mekong River has raised concerns as to the fragility of the Tonle Sap habitat due to any changing water levels and sedimentation rates within the lake. This paper details results of sub-bottom profiling surveys of Tonle Sap Lake in October 2014 that detailed the stratigraphy of the lake and assessed rates of infill. An Innomar Parametric Echo Sounder (PES) was used to obtain c. 250 km of sub-bottom profiles, with penetration up to 15m below the lake bed at a vertical resolution of c. 0.20m. These PES profiles were linked to cores from the north of the lake and previous literature. The PES profiles reveal a network of valleys, likely LGM, with relief up to c. 15-20m, that have been infilled by a suite of Holocene sediments. The valley surface is picked out as a strong reflector throughout the lake, and displays a series of valleys that are up to c. 15m deep and commonly 50-200m wide, although some of the largest valleys are 1.2km in width. Modelling of channel network incision during LGM conditions generates landscapes consistent with our field observations. The Tonle Sap valley network is infilled by sediments that show firstly fluvial and/or subaerial slope sedimentation, and then by extensive, parallel-bedded, lacustrine sedimentation. Lastly, the top c. 1m of sedimentation is marked by a distinct basal erosional surface that can be traced over much of the Tonle Sap Lake, and that is overlain by a series of parallel PES reflections. This upper sediment layer is interpreted to represent sedimentation in the Tonle Sap lake due to sediment suspension settling but after a period

  16. Surface-Layer (S-Layer) Proteins Sap and EA1 Govern the Binding of the S-Layer-Associated Protein BslO at the Cell Septa of Bacillus anthracis

    Science.gov (United States)

    Kern, Valerie J.; Kern, Justin W.; Theriot, Julie A.; Schneewind, Olaf

    2012-01-01

    The Gram-positive pathogen Bacillus anthracis contains 24 genes whose products harbor the structurally conserved surface-layer (S-layer) homology (SLH) domain. Proteins endowed with the SLH domain associate with the secondary cell wall polysaccharide (SCWP) following secretion. Two such proteins, Sap and EA1, have the unique ability to self-assemble into a paracrystalline layer on the surface of bacilli and form S layers. Other SLH domain proteins can also be found within the S layer and have been designated Bacillus S-layer-associated protein (BSLs). While both S-layer proteins and BSLs bind the same SCWP, their deposition on the cell surface is not random. For example, BslO is targeted to septal peptidoglycan zones, where it catalyzes the separation of daughter cells. Here we show that an insertional lesion in the sap structural gene results in elongated chains of bacilli, as observed with a bslO mutant. The chain length of the sap mutant can be reduced by the addition of purified BslO in the culture medium. This complementation in trans can be explained by an increased deposition of BslO onto the surface of sap mutant bacilli that extends beyond chain septa. Using fluorescence microscopy, we observed that the Sap S layer does not overlap the EA1 S layer and slowly yields to the EA1 S layer in a growth-phase-dependent manner. Although present all over bacilli, Sap S-layer patches are not observed at septa. Thus, we propose that the dynamic Sap/EA1 S-layer coverage of the envelope restricts the deposition of BslO to the SCWP at septal rings. PMID:22609927

  17. Patterns of ecosystem metabolism in the Tonle Sap Lake, Cambodia with links to capture fisheries.

    Directory of Open Access Journals (Sweden)

    Gordon W Holtgrieve

    Full Text Available The Tonle Sap Lake in Cambodia is a dynamic flood-pulsed ecosystem that annually increases its surface area from roughly 2,500 km(2 to over 12,500 km(2 driven by seasonal flooding from the Mekong River. This flooding is thought to structure many of the critical ecological processes, including aquatic primary and secondary productivity. The lake also has a large fishery that supports the livelihoods of nearly 2 million people. We used a state-space oxygen mass balance model and continuous dissolved oxygen measurements from four locations to provide the first estimates of gross primary productivity (GPP and ecosystem respiration (ER for the Tonle Sap. GPP averaged 4.1±2.3 g O2 m(-3 d(-1 with minimal differences among sites. There was a negative correlation between monthly GPP and lake level (r = 0.45 and positive correlation with turbidity (r = 0.65. ER averaged 24.9±20.0 g O2 m(-3 d(-1 but had greater than six-fold variation among sites and minimal seasonal change. Repeated hypoxia was observed at most sampling sites along with persistent net heterotrophy (GPPresource pathways that support this important ecosystem.

  18. Comparative Proteomic Analysis of Wild-Type and SAP Domain Mutant Foot-and-Mouth Disease Virus-Infected Porcine Cells Identifies the Ubiquitin-Activating Enzyme UBE1 Required for Virus Replication.

    Science.gov (United States)

    Zhu, Zixiang; Yang, Fan; Zhang, Keshan; Cao, Weijun; Jin, Ye; Wang, Guoqing; Mao, Ruoqing; Li, Dan; Guo, Jianhong; Liu, Xiangtao; Zheng, Haixue

    2015-10-02

    Leader protein (L(pro)) of foot-and-mouth disease virus (FMDV) manipulates the activities of several host proteins to promote viral replication and pathogenicity. L(pro) has a conserved protein domain SAP that is suggested to subvert interferon (IFN) production to block antiviral responses. However, apart from blocking IFN production, the roles of the SAP domain during FMDV infection in host cells remain unknown. Therefore, we identified host proteins associated with the SAP domain of L(pro) by a high-throughput quantitative proteomic approach [isobaric tags for relative and absolute quantitation (iTRAQ) in conjunction with liquid chromatography/electrospray ionization tandem mass spectrometry]. Comparison of the differentially regulated proteins in rA/FMDVΔmSAP- versus rA/FMDV-infected SK6 cells revealed 45 down-regulated and 32 up-regulated proteins that were mostly associated with metabolic, ribosome, spliceosome, and ubiquitin-proteasome pathways. The results also imply that the SAP domain has a function similar to SAF-A/B besides its potential protein inhibitor of activated signal transducer and activator of transcription (PIAS) function. One of the identified proteins UBE1 was further analyzed and displayed a novel role for the SAP domain of L(pro). Overexpression of UBE1 enhanced the replication of FMDV, and knockdown of UBE1 decreased FMDV replication. This shows that FMDV manipulates UBE1 for increased viral replication, and the SAP domain was involved in this process.

  19. Grapevine rootstock effects on scion sap phenolic levels, resistance to Xylella fastidiosa infection, and progression of Pierce’s disease

    Directory of Open Access Journals (Sweden)

    Christopher Michael Wallis

    2013-12-01

    Full Text Available The xylem-limited bacterium Xylella fastidiosa (Xf causes Pierce’s disease (PD, an important disease of grapevine, Vitis vinifera L.. Grapevine rootstocks were developed to provide increased resistance to root disease, but rootstock effects on cane and vine diseases remain unclear. Grapevines that consisted of Cabernet Sauvignon or Chardonnay grafted to 13 different rootstocks were inoculated with Xf and evaluated for PD severity and Xf titer after six months. A subset of six rootstock/scion combinations had xylem sap phenolic levels assessed in non-infected and Xf-infected grapevines. Vigor also was analyzed by measuring root lengths and masses. Cabernet Sauvignon grafted to 101-14MG, 1103P, 420A, or Schwarzmann had reduced PD severity compared to Cabernet Sauvignon grafted to 110R, 5BB, or SO4. Chardonnay grafted to Salt Creek or Freedom had reduced PD severity compared to Chardonnay grafted to RS3 or Schwarzmann. Chardonnay grafted to RS3 had greater Xf titer than Chardonnay grafted to 101-14MG, Freedom, or Salt Creek. No other differences in Xf titer among rootstocks were observed. Of the six scion/rootstock combinations which had xylem sap phenolics analyzed, Chardonnay/ RS3 had the highest levels of most phenolics whereas Cabernet Sauvignon/101-14MG had the lowest phenolic levels. However, Chardonnay/101-14MG, which had mild PD symptoms, had greater sap levels of caftaric acid than other scion/rootstock combinations. Sap levels of caftaric acid, methyl salicylate, a procyanidin trimer, and quinic acid were greater in Xf-infected versus non-infected grapevines. Chardonnay on 101-14MG or Salt Creek had greater root mass than Chardonnay on RS3. Cabernet Sauvignon on 101-14MG had greater root mass than Cabernet Sauvignon on 110R. These results identified rootstocks with the capacity for reducing PD symptom progression. Rootstocks also were shown to affect Xf titer, xylem sap phenolic levels, and plant vigor.

  20. Biotic and Abiotic Drivers of Sap Flux in Mature Green Ash Trees (Fraxinus pennsylvanica) Experiencing Varying Levels of Emerald Ash Borer (Agrilus planipennis) Infestation

    Science.gov (United States)

    Charles E. Flower; Douglas J. Lynch; Kathleen S. Knight; Miquel A.  Gonzalez-Meler

    2018-01-01

    While the relationship between abiotic drivers of sap flux are well established, the role of biotic disturbances on sap flux remain understudied. The invasion of the emerald ash borer (Agrilus planipennis Fairmaire, EAB) into North America in the 1990s represents a significant threat to ash trees (Fraxinus spp.), which are a...