WorldWideScience

Sample records for sand-water system laboratory

  1. Modification of streaming potential by precipitation of calcite in a sand-water system: laboratory measurements pH range from 4 to 12

    OpenAIRE

    Guichet, Xavier; Jouniaux, Laurence; Catel, Nicole

    2006-01-01

    The definitive version is available at www.blackwell-synergy.com; We acknowledge the Geophysical Journal International, the Royal Astronomical Society and Blackwell Publishing. Full bibliographic reference is : Guichet, X., L. Jouniaux, and N. Catel, Modification of streaming potential by precipitation of calcite in a sand-water system: laboratory measurements in the pH range from 4 to 12, Geophysical Journal International, 166, 445-460, doi:10.1111/j.1365-246X.2006.02922.x, 2006; Spontaneous...

  2. Neural Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — As part of the Electrical and Computer Engineering Department and The Institute for System Research, the Neural Systems Laboratory studies the functionality of the...

  3. Tactical Systems Integration Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Tactical Systems Integration Laboratory is used to design and integrate computer hardware and software and related electronic subsystems for tactical vehicles....

  4. Laboratory Information Systems.

    Science.gov (United States)

    Henricks, Walter H

    2015-06-01

    Laboratory information systems (LISs) supply mission-critical capabilities for the vast array of information-processing needs of modern laboratories. LIS architectures include mainframe, client-server, and thin client configurations. The LIS database software manages a laboratory's data. LIS dictionaries are database tables that a laboratory uses to tailor an LIS to the unique needs of that laboratory. Anatomic pathology LIS (APLIS) functions play key roles throughout the pathology workflow, and laboratories rely on LIS management reports to monitor operations. This article describes the structure and functions of APLISs, with emphasis on their roles in laboratory operations and their relevance to pathologists. Copyright © 2015 Elsevier Inc. All rights reserved.

  5. Specialized Laboratory Information Systems.

    Science.gov (United States)

    Dangott, Bryan

    2015-06-01

    Some laboratories or laboratory sections have unique needs that traditional anatomic and clinical pathology systems may not address. A specialized laboratory information system (LIS), which is designed to perform a limited number of functions, may perform well in areas where a traditional LIS falls short. Opportunities for specialized LISs continue to evolve with the introduction of new testing methodologies. These systems may take many forms, including stand-alone architecture, a module integrated with an existing LIS, a separate vendor-supplied module, and customized software. This article addresses the concepts underlying specialized LISs, their characteristics, and in what settings they are found. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Purdue Hydrogen Systems Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Jay P Gore; Robert Kramer; Timothee L Pourpoint; P. V. Ramachandran; Arvind Varma; Yuan Zheng

    2011-12-28

    The Hydrogen Systems Laboratory in a unique partnership between Purdue University's main campus in West Lafayette and the Calumet campus was established and its capabilities were enhanced towards technology demonstrators. The laboratory engaged in basic research in hydrogen production and storage and initiated engineering systems research with performance goals established as per the USDOE Hydrogen, Fuel Cells, and Infrastructure Technologies Program. In the chemical storage and recycling part of the project, we worked towards maximum recycling yield via novel chemical selection and novel recycling pathways. With the basic potential of a large hydrogen yield from AB, we used it as an example chemical but have also discovered its limitations. Further, we discovered alternate storage chemicals that appear to have advantages over AB. We improved the slurry hydrolysis approach by using advanced slurry/solution mixing techniques. We demonstrated vehicle scale aqueous and non-aqueous slurry reactors to address various engineering issues in on-board chemical hydrogen storage systems. We measured the thermal properties of raw and spent AB. Further, we conducted experiments to determine reaction mechanisms and kinetics of hydrothermolysis in hydride-rich solutions and slurries. We also developed a continuous flow reactor and a laboratory scale fuel cell power generation system. The biological hydrogen production work summarized as Task 4.0 below, included investigating optimal hydrogen production cultures for different substrates, reducing the water content in the substrate, and integrating results from vacuum tube solar collector based pre and post processing tests into an enhanced energy system model. An automated testing device was used to finalize optimal hydrogen production conditions using statistical procedures. A 3 L commercial fermentor (New Brunswick, BioFlo 115) was used to finalize testing of larger samples and to consider issues related to scale up

  7. Protective Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — This laboratory is a 40 by 28 by 9 foot facility that is equipped with tools for the development of various items of control technology related to the transmission...

  8. The Computational Sensorimotor Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Computational Sensorimotor Systems Lab focuses on the exploration, analysis, modeling and implementation of biological sensorimotor systems for both scientific...

  9. Propulsion Systems Laboratory, Bldg. 125

    Data.gov (United States)

    Federal Laboratory Consortium — The Propulsion Systems Laboratory (PSL) is NASAs only ground test facility capable of providing true altitude and flight speed simulation for testing full scale gas...

  10. An Investigation into Air-Sand-Water Three-Phase Flow through the Sandblasting Nozzle

    Directory of Open Access Journals (Sweden)

    M. Abbasalizadeh

    2013-09-01

    Full Text Available The numerical analysis of air-sand-water three-phase turbulent flow through converging-diverging nozzle is investigated for employing on sandblasting systems. For this purpose-dispersed flow of air-sand-water by various airs inlet pressures and different mass flow rates of sand particles and water droplets were considered. Two-way turbulence coupling between particles/droplets and airflow as well as interference between the incident streams of particles and rebounded from the wall were applied in the numerical model. In addition, the shock wave, which is produced in supersonic flow at diverging part of nozzle, was considered. In this study the Realizable k-ε and Discrete Phase models were utilized for simulating of multi-phase turbulent flow through the converging-diverging nozzle. As review of literature indicates there is not any experimental or analytical data on three-phase flow through the nozzle, consequently for validation of model, the same turbulent and multi-phase models were utilized on air-water two-phase flow. The obtained results were in good agreement with the experimental data. According to the results of three-phase flow simulation, the averaged exhaust momentum of sand particles had inverse proportion with water mass flow rate, and increasing of air inlet pressure had significant effect on mean exhaust velocity of sand particles.

  11. Communication Systems Analysis Laboratory (CSAL)

    Data.gov (United States)

    Federal Laboratory Consortium — CSAL conducts electronic warfare investigations of radio frequency communication systems with respect to current and emerging electronic warfare threats. CSAL uses...

  12. Semi-Autonomous Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — VisionThe Semi-Autonomous Systems Lab focuses on developing a comprehensive framework for semi-autonomous coordination of networked robotic systems. Semi-autonomous...

  13. LABORATORY VOICE DATA ENTRY SYSTEM.

    Energy Technology Data Exchange (ETDEWEB)

    PRAISSMAN,J.L.SUTHERLAND,J.C.

    2003-04-01

    We have assembled a system using a personal computer workstation equipped with standard office software, an audio system, speech recognition software and an inexpensive radio-based wireless microphone that permits laboratory workers to enter or modify data while performing other work. Speech recognition permits users to enter data while their hands are holding equipment or they are otherwise unable to operate a keyboard. The wireless microphone allows unencumbered movement around the laboratory without a ''tether'' that might interfere with equipment or experimental procedures. To evaluate the potential of voice data entry in a laboratory environment, we developed a prototype relational database that records the disposal of radionuclides and/or hazardous chemicals Current regulations in our laboratory require that each such item being discarded must be inventoried and documents must be prepared that summarize the contents of each container used for disposal. Using voice commands, the user enters items into the database as each is discarded. Subsequently, the program prepares the required documentation.

  14. Aviation Information Systems Development Laboratory (AISDL)

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose:The Aviation Information Systems Development Laboratory (AISDL) provides the tools, reconfigurability and support to ensure the quality and integrity of new...

  15. Region 7 Laboratory Information Management System

    Data.gov (United States)

    U.S. Environmental Protection Agency — This is metadata documentation for the Region 7 Laboratory Information Management System (R7LIMS) which maintains records for the Regional Laboratory. Any Laboratory...

  16. Quality system for Medical laboratories

    Directory of Open Access Journals (Sweden)

    Shiva Raj K.C.

    2015-03-01

    Full Text Available According to William Edwards Deming “Good quality does not necessarily mean high quality. Instead it means a predicable degree of uniformity and dependability at low cost with a quality suited to the market.” Whereas according to famous engineer and management consultant Joseph M. Juran quality is “fitness for purpose”. It should meet the customers’ expectations and requirements, should be cost effective.ISO began in 1926 as the International Federation of the National Standardizing Associations (ISA. The name, "ISO" was derived from the Greek word "isos" meaning "equal". (The relation to standards is that if two objects meet the same standard, they should be equal. This name eliminates any confusion that could result from the translation of "International Organization for Standardization" into different languages which would lead to different acronyms.In health sector, quality plays pivotal role, as it is directly related to patient’s care. Earlier time, health service was simple, quite safe but ineffective. Now health care system is an organizational system with more complex processes to deliver care. Medical laboratory service is an integral part in patient’s management system. So, for everyone involved in the treatment of the patient, the accuracy, reliability and safety of those services must be the primary concerns. Accreditation is a significant enabler of quality, thereby delivering confidence to healthcare providers, clinicians, the medical laboratories and the patients themselves.ISO announced meeting in Philadelphia to form a technical committee to develop a new standard for medical laboratory quality. It took 7 years for the creation of a new Quality standard for medical laboratories. It was named as “ISO 15189” and was first published in 2003. The ISO has released three versions of the standard. The first two were released in 2003 and 2007. In 2012, a revised and updated version of the standard, ISO 15189

  17. Robotics and Autonomous Systems Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides an environment for developing and evaluating intelligent software for both actual and simulated autonomous vehicles. Laboratory computers provide...

  18. Road Transportable Analytical Laboratory (RTAL) system

    Energy Technology Data Exchange (ETDEWEB)

    Finger, S.M. [Engineering Computer Optecnomics, Inc., Annapolis, MD (United States)

    1995-10-01

    The goal of the Road Transportable Analytical Laboratory (RTAL) Project is the development and demonstration of a system to meet the unique needs of the DOE for rapid, accurate analysis of a wide variety of hazardous and radioactive contaminants in soil, groundwater, and surface waters. This laboratory system has been designed to provide the field and laboratory analytical equipment necessary to detect and quantify radionuclides, organics, heavy metals and other inorganic compounds. The laboratory system consists of a set of individual laboratory modules deployable independently or as an interconnected group to meet each DOE site`s specific needs.

  19. Research System Integration Laboratory (SIL)

    Data.gov (United States)

    Federal Laboratory Consortium — The VEA Research SIL (VRS) is essential to the success of the TARDEC 30-Year Strategy. The vast majority of the TARDEC Capability Sets face challenging electronics...

  20. Simulation-Based System Design Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The research objective is to develop, test, and implement effective and efficient simulation techniques for modeling, evaluating, and optimizing systems in order to...

  1. Region 7 Laboratory Information Management System

    Science.gov (United States)

    This is metadata documentation for the Region 7 Laboratory Information Management System (R7LIMS) which maintains records for the Regional Laboratory. Any Laboratory analytical work performed is stored in this system which replaces LIMS-Lite, and before that LAST. The EPA and its contractors may use this database. The Office of Policy & Management (PLMG) Division at EPA Region 7 is the primary managing entity; contractors can access this database but it is not accessible to the public.

  2. Seawater circulating system in an aquaculture laboratory

    Digital Repository Service at National Institute of Oceanography (India)

    Chatterji, A.; Ingole, B.S.; Parulekar, A.H.

    The note gives an account, for the first time in India, of an Aquaculture Laboratory with open type seawater circulating system developed at the National Institute of Oceanography, Goa, India. Besides describing the details of the system...

  3. Intelligent Acquisition System Used in Mechanical Laboratory

    Directory of Open Access Journals (Sweden)

    Rob Raluca

    2016-01-01

    Full Text Available The main purpose of this paper consists in determining of the parameters which characterize the functioning of the Teves MK 60 as an ABS-ESP braking laboratory stand. This braking system model is used by the Volkswagen Golf and Bora the since 2002. The braking laboratory stand is able to simulate many operations which are able to give information concerning the ABS-ESP braking system comparing to the classical braking system. An application designed in LabVIEW comes to acquire and to process in real time the electrical signals generated by the Teves MK 60 laboratory stand.

  4. Assessment of laboratory logistics management information system ...

    African Journals Online (AJOL)

    Results: There exists a well-designed logistics system for laboratory commodities with trained pharmacy personnel, distributed standard LMIS formats and established inventory control procedures. However, majority of laboratory professionals were not trained in LMIS. Majority of the facilities (60.5%) were stocked out for at ...

  5. Laboratory testing & measurement on optical imaging systems

    CSIR Research Space (South Africa)

    Theron, B

    2013-04-01

    Full Text Available The purpose of the workshop was for participants to interactively discuss (with regard to optical imaging or optical imaging systems): Local end-user needs; What those needs imply for associated new & existing laboratory testing & measurement...

  6. Sandia Laboratories technical capabilities: computation systems

    Energy Technology Data Exchange (ETDEWEB)

    1977-12-01

    This report characterizes the computation systems capabilities at Sandia Laboratories. Selected applications of these capabilities are presented to illustrate the extent to which they can be applied in research and development programs. 9 figures.

  7. Medical laboratory quality systems - a management review.

    Science.gov (United States)

    Theodorou, Dimitris; Giannelos, Padelis

    2015-01-01

    The purpose of this paper is to highlight changes in ISO 15189:2012 and ISO 15189:2007 concerning management review requirements and to present a management review checklist, which includes all the revised ISO 15189's requirements. The recent revised and updated ISO 15189:2012 standard recommends a management review using a process approach and includes some additional topics. The management review is a key element in many quality management systems, including medical laboratory management systems in accordance with ISO 15189. The process approach enables laboratory top managers and personnel to achieve all the quality management system's important inputs and outputs. As laboratory staff often encounter difficulties fully exploiting the management review process, this checklist helps laboratory staff carry out an effective management review covering all the quality management system's important aspects.

  8. Skylab food system laboratory support

    Science.gov (United States)

    Sanford, D.

    1974-01-01

    A summary of support activities performed to ensure the quality and reliability of the Skylab food system design is reported. The qualification test program was conducted to verify crew compartment compatibility, and to certify compliance of the food system with nutrition, preparation, and container requirements. Preflight storage requirements and handling procedures were also determined. Information on Skylab food items was compiled including matters pertaining to serving size, preparation information, and mineral, calorie, and protein content. Accessory hardware and the engraving of food utensils were also considered, and a stowage and orientation list was constructed which takes into account menu use sequences, menu items, and hardware stowage restrictions. A food inventory system was established and food thermal storage tests were conducted. Problems and comments pertaining to specific food items carried onboard the Skylab Workshop were compiled.

  9. Systems integration test laboratory application & experiences

    Science.gov (United States)

    Rimer, Melvyn; Falco, Michael; Solan, Michael J.

    1991-01-01

    The ability to safely control highly dynamic systems is of prime importance to designers. Whether the system is an aircraft, spacecraft, or propulsion system, control system designers must turn to test laboratories not only to verify and validate the control systems, but also to actually use the laboratory as a design and development tool. The use of the laboratory early in the development phase of a system—prior to committing to actual hardware/software (HW/SW)—permits early detection of system anomalies, thereby minimizing program development costs while enhancing safety. Later the laboratory can be used to train system operators (for example, pilots, ground crew) in preparation for flight/ground test. In the case of the statically unstable X-29 forward swept wing aircraft, a comprehensive real-time, hardware-in-the-loop test facility was critical in the development of the aircraft's digital fly-by-wire (FBW) flight control system. The X-29 laboratory initially was used to introduce control laws to a simulated real-time environment to verify control system characteristics. Later, actual flight hardware was introduced to the laboratory, at which point the formal system verification/validation test program began. The test program utilized detailed test plans and procedures derived from system requirements and specifications to map out all tests required. This assured that the maximum number of components of the system were exercised in the laboratory, and all components tested had traceability throughout the test program. The end-to-end hardware-in-the loop simulation provided the environment to perform critical failure modes testing, parameter sensitivity evaluation and ultimately pilot/ground crew training during normal and degraded flight control system operation. The X-29 test experience, applicable to the laboratory testing of all critical control systems, has ingrained the philosophy that successful development of complex systems requires an orderly build

  10. Microprocessor-Based Laboratory Data Acquisition Systems.

    Science.gov (United States)

    Woodard, F. E.; And Others

    1981-01-01

    Focuses on attributes of microcomputer systems which affect their usefulness in a laboratory environment. In addition to presenting general concepts, comments are made regarding the implementation of these concepts using a microprocessor-based data acquisition system developed at the University of North Carolina. (CO)

  11. A Wireless Communications Systems Laboratory Course

    Science.gov (United States)

    Guzelgoz, Sabih; Arslan, Huseyin

    2010-01-01

    A novel wireless communications systems laboratory course is introduced. The course teaches students how to design, test, and simulate wireless systems using modern instrumentation and computer-aided design (CAD) software. One of the objectives of the course is to help students understand the theoretical concepts behind wireless communication…

  12. Protocol for Measuring the Thermal Properties of a Supercooled Synthetic Sand-water-gas-methane Hydrate Sample.

    Science.gov (United States)

    Muraoka, Michihiro; Susuki, Naoko; Yamaguchi, Hiroko; Tsuji, Tomoya; Yamamoto, Yoshitaka

    2016-03-21

    Methane hydrates (MHs) are present in large amounts in the ocean floor and permafrost regions. Methane and hydrogen hydrates are being studied as future energy resources and energy storage media. To develop a method for gas production from natural MH-bearing sediments and hydrate-based technologies, it is imperative to understand the thermal properties of gas hydrates. The thermal properties' measurements of samples comprising sand, water, methane, and MH are difficult because the melting heat of MH may affect the measurements. To solve this problem, we performed thermal properties' measurements at supercooled conditions during MH formation. The measurement protocol, calculation method of the saturation change, and tips for thermal constants' analysis of the sample using transient plane source techniques are described here. The effect of the formation heat of MH on measurement is very small because the gas hydrate formation rate is very slow. This measurement method can be applied to the thermal properties of the gas hydrate-water-guest gas system, which contains hydrogen, CO2, and ozone hydrates, because the characteristic low formation rate of gas hydrate is not unique to MH. The key point of this method is the low rate of phase transition of the target material. Hence, this method may be applied to other materials having low phase-transition rates.

  13. Modeling of sand-water slurry flow through horizontal pipe using CFD

    Directory of Open Access Journals (Sweden)

    Kumar Gopaliya Manoj

    2016-09-01

    Full Text Available The paper presents three-dimensional CFD analysis of two-phase (sand-water slurry flows through 263 mm diameter pipe in horizontal orientation for mixture velocity range of 3.5-4.7 m/s and efflux concentration range of 9.95-34% with three particle sizes viz. 0.165 mm, 0.29 mm and 0.55 mm with density 2650 kg/m3. RNG k-ε turbulence closure equations with Eulerian multi-phase model is used to simulate various slurry flows. The simulated values of local solid concentration are compared with the experimental data and are found to be in good agreement for all particle sizes. Effects of particle size on various slurry flow parameters such as pressure drop, solid phase velocity distribution, friction factor, granular pressure, turbulent viscosity, turbulent kinetic energy and its dissipation have been analyzed.

  14. CMDS System Integration and IAMD End-to-End Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Cruise Missile Defense Systems (CMDS) Project Office is establishing a secure System Integration Laboratory at the AMRDEC. This lab will contain tactical Signal...

  15. Authoring Systems for Laboratory Experiment Simulators.

    Science.gov (United States)

    Shacham, Mordechai; Cutlip, Michael B.

    1988-01-01

    Discussion of laboratory experiment simulation in science and engineering education focuses on the need for authoring systems that can be used to create simulations. An editor for a simulator model containing variables and mathematical equations is presented, and screen displays and data analysis are discussed. (LRW)

  16. Road Transportable Analytical Laboratory system. Phase 1

    Energy Technology Data Exchange (ETDEWEB)

    Finger, S.M.; Keith, V.F.; Spertzel, R.O.; De Avila, J.C.; O`Donnell, M.; Vann, R.L.

    1993-09-01

    This developmental effort clearly shows that a Road Transportable Analytical Laboratory System is a worthwhile and achievable goal. The RTAL is designed to fully analyze (radioanalytes, and organic and inorganic chemical analytes) 20 samples per day at the highest levels of quality assurance and quality control. It dramatically reduces the turnaround time for environmental sample analysis from 45 days (at a central commercial laboratory) to 1 day. At the same time each RTAL system will save the DOE over $12 million per year in sample analysis costs compared to the costs at a central commercial laboratory. If RTAL systems were used at the eight largest DOE facilities (at Hanford, Savannah River, Fernald, Oak Ridge, Idaho, Rocky Flats, Los Alamos, and the Nevada Test Site), the annual savings would be $96,589,000. The DOE`s internal study of sample analysis needs projects 130,000 environmental samples requiring analysis in FY 1994, clearly supporting the need for the RTAL system. The cost and time savings achievable with the RTAL system will accelerate and improve the efficiency of cleanup and remediation operations throughout the DOE complex.

  17. HSI Prototypes for Human Systems Simulation Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Jokstad, Håkon [Idaho National Lab. (INL), Idaho Falls, ID (United States); McDonald, Rob [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-09-01

    This report describes in detail the design and features of three Human System Interface (HSI) prototypes developed by the Institutt for Energiteknikk (IFE) in support of the U.S. Department of Energy’s Light Water Reactor Sustainability Program under Contract 128420 through Idaho National Laboratory (INL). The prototypes are implemented for the Generic Pressurized Water Reactor simulator and installed in the Human Systems Simulation Laboratory at INL. The three prototypes are: 1) Power Ramp display 2) RCS Heat-up and Cool-down display 3) Estimated time to limit display The power ramp display and the RCS heat-up/cool-down display are designed to provide good visual indications to the operators on how well they are performing their task compared to their target ramp/heat-up/cool-down rate. The estimated time to limit display is designed to help operators restore levels or pressures before automatic or required manual actions are activated.

  18. Public health laboratory systems development in East Africa through ...

    African Journals Online (AJOL)

    Public health laboratory systems development in East Africa through training in laboratory management and field epidemiology. Fausta Mosha, Joseph Oundo, David Mukanga, Kariuki Njenga, Peter Nsubuga ...

  19. Whole-building systems integration laboratory survey

    Energy Technology Data Exchange (ETDEWEB)

    Crawley, D.B. (American Consulting Engineers Council, Washington, DC (USA). Research and Management Foundation)

    1989-09-01

    This report was prepared for the Pacific Northwest Laboratory as a subcontracted activity by the Research Management Foundation of the American Consulting Engineers Council. The objective of the survey reported herein was to independently assess the need for a Building System Integration Laboratory from the viewpoint of academicians in the field of building science. The subcontractor-developed questionnaire was sent to 200 professors of architecture and engineering at US universities. In view of this diverse population, the 10% rate of return on the questionnaire was considered acceptable. Although the responses probably do not reflect an unbiased summary of the collective perceptions of the original population surveyed, they do provide a valid insight into the interests and concerns of the academic community with respect to building sciences issues.

  20. INFORMATION SYSTEM ELAB FOR ACCREDITED TESTING LABORATORIES

    Directory of Open Access Journals (Sweden)

    S. N. Sytovа

    2017-01-01

    Full Text Available The basic principles of organization and algorithms of information system eLab operation for accredited testing laboratories based on free software are described. The system runs under Windows and Linux. The work is carried out through the Web-interface in multi-user mode with the sharing the access rights through widely distributed browsers installed on the users' desktops. The software composition, problems of security and the enhancement of the functionality of the system, as well as the organizational chart of the software and the hierarchy of basic classes are discussed in detail. The algorithm of secure connection to the database and the algorithm for installation of the system software on the server are given.

  1. Model Driven Laboratory Information Management Systems

    Science.gov (United States)

    Li, Hao; Gennari, John H.; Brinkley, James F.

    2006-01-01

    Scientists in small research labs need more robust tools than spreadsheets to manage their data. However, no suitable laboratory information management systems (LIMS) are readily available; they are either too costly or too complex. We have therefore developed Seedpod, a model driven LIMS that allows users to create an integrated model of a LIMS without programming. Seedpod then automatically produces a relational database from the model, and dynamically generates a web-based graphical user interface. Our goal is to make LIMS easier to use by decreasing development time and cost, thereby allowing researchers to focus on producing and collecting data. PMID:17238388

  2. Usability Evaluation of Laboratory Information Systems.

    Science.gov (United States)

    Mathews, Althea; Marc, David

    2017-01-01

    Numerous studies have revealed widespread clinician frustration with the usability of electronic health records (EHRs) that is counterproductive to adoption of EHR systems to meet the aims of health-care reform. With poor system usability comes increased risk of negative unintended consequences. Usability issues could lead to user error and workarounds that have the potential to compromise patient safety and negatively impact the quality of care.[1] While there is ample research on EHR usability, there is little information on the usability of laboratory information systems (LISs). Yet, LISs facilitate the timely provision of a great deal of the information needed by physicians to make patient care decisions.[2] Medical and technical advances in genomics that require processing of an increased volume of complex laboratory data further underscore the importance of developing user-friendly LISs. This study aims to add to the body of knowledge on LIS usability. A survey was distributed among LIS users at hospitals across the United States. The survey consisted of the ten-item System Usability Scale (SUS). In addition, participants were asked to rate the ease of performing 24 common tasks with a LIS. Finally, respondents provided comments on what they liked and disliked about using the LIS to provide diagnostic insight into LIS perceived usability. The overall mean SUS score of 59.7 for the LIS evaluated is significantly lower than the benchmark of 68 ( P effect of years of experience and LIS used did not account for the statistically significant difference in the mean SUS score between Orchard Harvest and each of the other LISs evaluated. The results of this study indicate that overall usability of LISs is poor. Usability lags that of systems evaluated across 446 usability surveys.

  3. From Laboratory Manipulations To Earth System Models

    Science.gov (United States)

    Ridgwell, A.; Schmidt, D.

    2008-12-01

    The apparent incongruence between coccolithophore calcification responses observed across different experimental manipulations, particularly those involving Emiliania huxleyi, raises new challenges particularly for modellers. This is because the global models used for predicting future fossil fuel CO2 uptake by the ocean base their parameterizations for plankton calcification and carbonate export from the ocean surface closely on laboratory results. Predictions of such models will be unreliable if rooted in unrepresentative and/or poorly understood laboratory experiments. The difficulty in making sense of the differing responses reported and thus correctly informing models is compounded by fundamental differences between laboratory culture studies, particularly in the strain (ecotype or likely even genotype) of E. huxleyi cultured. However, two pertinent observations offer the promise of resolving these difficulties: (1) experiments using other coccolithophore species have delineated the existence of a calcification 'optimum' in environmental conditions (pH), and (2) there is an unambiguous direction to the calcification-CO2 response in mesocosm and shipboard incubations. We propose that an equivalence can be drawn between species or even ecosystem integrated phytoplankton calcification rate as a function of pH (or saturation), and widely used descriptions of plankton growth rate vs. temperature (the Eppley curve). An 'Eppley' like calcification formulation provides not only a conceptual framework for reconciling the results of available experimental manipulations of coccolithophores, but also a means of constructing a simple quasi-empirical relationship for describing ocean acidification impacts on planktonic carbonate production in carbon cycle models. The implications of this for future fossil fuel CO2 uptake by the ocean are assessed in an Earth system model.

  4. Usability evaluation of laboratory information systems

    Directory of Open Access Journals (Sweden)

    Althea Mathews

    2017-01-01

    Full Text Available Background: Numerous studies have revealed widespread clinician frustration with the usability of electronic health records (EHRs that is counterproductive to adoption of EHR systems to meet the aims of health-care reform. With poor system usability comes increased risk of negative unintended consequences. Usability issues could lead to user error and workarounds that have the potential to compromise patient safety and negatively impact the quality of care.[1] While there is ample research on EHR usability, there is little information on the usability of laboratory information systems (LISs. Yet, LISs facilitate the timely provision of a great deal of the information needed by physicians to make patient care decisions.[2] Medical and technical advances in genomics that require processing of an increased volume of complex laboratory data further underscore the importance of developing user-friendly LISs. This study aims to add to the body of knowledge on LIS usability. Methods: A survey was distributed among LIS users at hospitals across the United States. The survey consisted of the ten-item System Usability Scale (SUS. In addition, participants were asked to rate the ease of performing 24 common tasks with a LIS. Finally, respondents provided comments on what they liked and disliked about using the LIS to provide diagnostic insight into LIS perceived usability. Results: The overall mean SUS score of 59.7 for the LIS evaluated is significantly lower than the benchmark of 68 (P < 0.001. All LISs evaluated received mean SUS scores below 68 except for Orchard Harvest (78.7. While the years of experience using the LIS was found to be a statistically significant influence on mean SUS scores, the combined effect of years of experience and LIS used did not account for the statistically significant difference in the mean SUS score between Orchard Harvest and each of the other LISs evaluated. Conclusions: The results of this study indicate that overall

  5. NCAR Earth Observing Laboratory's Data Tracking System

    Science.gov (United States)

    Cully, L. E.; Williams, S. F.

    2014-12-01

    The NCAR Earth Observing Laboratory (EOL) maintains an extensive collection of complex, multi-disciplinary datasets from national and international, current and historical projects accessible through field project web pages (https://www.eol.ucar.edu/all-field-projects-and-deployments). Data orders are processed through the EOL Metadata Database and Cyberinfrastructure (EMDAC) system. Behind the scenes is the institutionally created EOL Computing, Data, and Software/Data Management Group (CDS/DMG) Data Tracking System (DTS) tool. The DTS is used to track the complete life cycle (from ingest to long term stewardship) of the data, metadata, and provenance for hundreds of projects and thousands of data sets. The DTS is an EOL internal only tool which consists of three subsystems: Data Loading Notes (DLN), Processing Inventory Tool (IVEN), and Project Metrics (STATS). The DLN is used to track and maintain every dataset that comes to the CDS/DMG. The DLN captures general information such as title, physical locations, responsible parties, high level issues, and correspondence. When the CDS/DMG processes a data set, IVEN is used to track the processing status while collecting sufficient information to ensure reproducibility. This includes detailed "How To" documentation, processing software (with direct links to the EOL Subversion software repository), and descriptions of issues and resolutions. The STATS subsystem generates current project metrics such as archive size, data set order counts, "Top 10" most ordered data sets, and general information on who has ordered these data. The DTS was developed over many years to meet the specific needs of the CDS/DMG, and it has been successfully used to coordinate field project data management efforts for the past 15 years. This paper will describe the EOL CDS/DMG Data Tracking System including its basic functionality, the provenance maintained within the system, lessons learned, potential improvements, and future developments.

  6. NETLab: An Online Laboratory Management System

    OpenAIRE

    Ananda Maiti

    2010-01-01

    Online hardware-based educational laboratories are increasingly being deployed in traditional on-campus as well as Web-based distance-learning courses around the world. An online laboratory generally will consist of several hardware-based remote experiments. However, one particular experiment can be performed at a time by an individual student or a group of students which require a careful scheduling of the experiments. For the proper implementation of an online laboratory an efficient labora...

  7. (SLMTA) on laboratory quality management system in city ...

    African Journals Online (AJOL)

    SLMTA) is a competency-based management training programme designed to bring about immediate and measurable laboratory improvement. The aim of this study is to assess the outcome of SLMTA on laboratory quality management system in ...

  8. State public health laboratory system quality improvement activities.

    Science.gov (United States)

    Su, Bertina; Vagnone, Paula Snippes

    2013-01-01

    The Association of Public Health Laboratories (APHL) and the APHL Laboratory Systems and Standards Committee manage the Laboratory System Improvement Program (L-SIP). One component of L-SIP is an assessment that allows the members and stakeholders of a laboratory system to have an open and honest discussion about the laboratory system's strengths and weaknesses. From these facilitated discussions, gaps and opportunities for improvement are identified. In some cases, ideas for how to best address these gaps emerge, and workgroups are formed. Depending on resources, both monetary and personnel, laboratory staff will then prioritize the next component of L-SIP: which quality improvement activities to undertake. This article describes a sample of quality improvement activities initiated by several public health laboratories after they conducted L-SIP assessments. These projects can result in more robust linkages between system entities, which can translate into improvements in the way the system addresses the needs of stakeholders.

  9. AUTOMATION OF THE SYSTEM OF INTERNAL LABORATORY QUALITY CONTROL

    Directory of Open Access Journals (Sweden)

    V. Z. Stetsyuk

    2015-05-01

    Full Text Available Quality control system base d on the principles of standardi zation of all phases of laboratory testing and analysis of internal laboratory quality control and external quality assessment. For the detection accuracy of the results of laboratory tests, carried out internally between the laboratory and laboratory quality control. Under internal laboratory quality control we understand measurement results of each analysis in each anal ytical series rendered directly in the lab every day. The purpose of internal laboratory control - identifying and eliminating unacceptable deviations from standard perfor mance test in the laboratory, i.e. identifying and eliminating harmful analytical errors. The solutions to these problems by implementing automated systems - software that allows you to optimize analytical laboratory research stage of the procedure by automatically creating process control charts was shown.

  10. Mining of hospital laboratory information systems

    DEFF Research Database (Denmark)

    Søeby, Karen; Jensen, Peter Bjødstrup; Werge, Thomas

    2015-01-01

    in creatinine levels at different time points after birth and around the early teens, which challenges the establishment and usefulness of reference intervals in those age groups. Conclusions: The study documents that hospital laboratory data may inform on the developmental aspects of creatinine, on periods......Abstract Background: The knowledge of physiological fluctuation and variation of even commonly used biochemical quantities in extreme age groups and during development is sparse. This challenges the clinical interpretation and utility of laboratory tests in these age groups. To explore the utility...... of hospital laboratory data as a source of information, we analyzed enzymatic plasma creatinine as a model analyte in two large pediatric hospital samples. Methods: Plasma creatinine measurements from 9700 children aged 0-18 years were obtained from hospital laboratory databases and partitioned into high...

  11. Evaluating Usability in a Distance Digital Systems Laboratory Class

    Science.gov (United States)

    Kostaras, N.; Xenos, M.; Skodras, A. N.

    2011-01-01

    This paper presents the usability evaluation of a digital systems laboratory class offered to distance-learning students. It details the way in which students can participate remotely in such a laboratory, the methodology employed in the usability assessment of the laboratory infrastructure (hardware and software), and also outlines the main…

  12. Automated Medical Information System of the Los Alamos Scientific Laboratory

    OpenAIRE

    Eagan, Gerald D.; Grier, Robert S.

    1980-01-01

    The Medical Information System (MIS) at the Los Alamos Scientific Laboratory automates the acquisition, storage and retrieval of medical information concerning the nine thousand project-connected personnel.

  13. [Knowledge management system for laboratory work and clinical decision support].

    Science.gov (United States)

    Inada, Masanori; Sato, Mayumi; Yoneyama, Akiko

    2011-05-01

    This paper discusses a knowledge management system for clinical laboratories. In the clinical laboratory of Toranomon Hospital, we receive about 20 questions relevant to laboratory tests per day from medical doctors or co-medical staff. These questions mostly involve the essence to appropriately accomplish laboratory tests. We have to answer them carefully and suitably because an incorrect answer may cause a medical accident. Up to now, no method has been in place to achieve a rapid response and standardized answers. For this reason, the laboratory staff have responded to various questions based on their individual knowledge. We began to develop a knowledge management system to promote the knowledge of staff working for the laboratory. This system is a type of knowledge base for assisting the work, such as inquiry management, laboratory consultation, process management, and clinical support. It consists of several functions: guiding laboratory test information, managing inquiries from medical staff, reporting results of patient consultation, distributing laboratory staffs notes, and recording guidelines for laboratory medicine. The laboratory test information guide has 2,000 records of medical test information registered in the database with flexible retrieval. The inquiry management tool provides a methos to record all questions, answer easily, and retrieve cases. It helps staff to respond appropriately in a short period of time. The consulting report system treats patients' claims regarding medical tests. The laboratory staffs notes enter a file management system so they can be accessed to aid in clinical support. Knowledge sharing using this function can achieve the transition from individual to organizational learning. Storing guidelines for laboratory medicine will support EBM. Finally, it is expected that this system will support intellectual activity concerning laboratory work and contribute to the practice of knowledge management for clinical work support.

  14. Laboratory services series: a programmed maintenance system

    Energy Technology Data Exchange (ETDEWEB)

    Tuxbury, D.C.; Srite, B.E.

    1980-01-01

    The diverse facilities, operations and equipment at a major national research and development laboratory require a systematic, analytical approach to operating equipment maintenance. A computer-scheduled preventive maintenance program is described including program development, equipment identification, maintenance and inspection instructions, scheduling, personnel, and equipment history.

  15. Laboratory Tests of Small SDHW Systems

    DEFF Research Database (Denmark)

    Furbo, Simon; Shah, Louise Jivan

    1997-01-01

    A test facility for Small SDHW systems was built in 1992. In the test facility up to 10 SDHW systems can be tested side-by-side under the same realistic conditions. Since 1992 16 different systems have been tested in the facility. Both test systems and marketed systems from Danish as well as fore...

  16. Taking the risk out of laboratory information systems.

    Science.gov (United States)

    Winsten, D I

    1992-01-01

    Laboratory information systems (LISs) help laboratories deal effectively with regulations, technological change, economic pressures, and increased competition. Because they are such an essential part of the laboratory, it makes sense to do everything you can to reduce the risks associated with LISs. This article examines six areas of risk that could affect the successful acquisition and implementation of an LIS--vendor corporate failure, system failure, additional costs, delays in implementation, obsolescence, and noncompliance with regulations--and offers suggestions to help laboratory managers avoid these risk areas.

  17. Aircraft wire system laboratory development : phase I progress report.

    Energy Technology Data Exchange (ETDEWEB)

    Dinallo, Michael Anthony; Lopez, Christopher D.

    2003-08-01

    An aircraft wire systems laboratory has been developed to support technical maturation of diagnostic technologies being used in the aviation community for detection of faulty attributes of wiring systems. The design and development rationale of the laboratory is based in part on documented findings published by the aviation community. The main resource at the laboratory is a test bed enclosure that is populated with aged and newly assembled wire harnesses that have known defects. This report provides the test bed design and harness selection rationale, harness assembly and defect fabrication procedures, and descriptions of the laboratory for usage by the aviation community.

  18. Fire safety evaluation system for NASA office/laboratory buildings

    Science.gov (United States)

    Nelson, H. E.

    1986-11-01

    A fire safety evaluation system for office/laboratory buildings is developed. The system is a life safety grading system. The system scores building construction, hazardous areas, vertical openings, sprinklers, detectors, alarms, interior finish, smoke control, exit systems, compartmentation, and emergency preparedness.

  19. Laboratory Information Management System Chain of Custody: Reliability and Security

    OpenAIRE

    Tomlinson, J. J.; Elliott-Smith, W.; Radosta, T.

    2006-01-01

    A chain of custody (COC) is required in many laboratories that handle forensics, drugs of abuse, environmental, clinical, and DNA testing, as well as other laboratories that want to assure reliability of reported results. Maintaining a dependable COC can be laborious, but with the recent establishment of the criteria for electronic records and signatures by US regulatory agencies, laboratory information management systems (LIMSs) are now being developed to fully automate COCs. The extent of a...

  20. Cinematography Data Systems At The Naval Biodynamics Laboratory

    Science.gov (United States)

    Willems, G.; Muzzy, W.; Anderson, W.; Becker, E.

    1982-02-01

    The Naval Biodynamics Laboratory in New Orleans, Louisiana is engaged in a series of experiments to measure the dynamic response of critical anatomical segments of the human anatomy to acceleration environments. A comprehensive three-dimensional cinematographic data acquisition system is employed to obtain the required trajectory data. This paper presents an overview of the entire Naval Biodynamics Laboratory system: described are the hardware employed, calibration requirements and methodology, data reduction and analysis, and timing systems.

  1. Multipurpose laboratory test system applying CAMAC standards

    Energy Technology Data Exchange (ETDEWEB)

    Bowers, J.L.

    1976-11-01

    A flexible electronic product test and evaluation system is proposed. A system study was performed to determine how increasingly complex telemetry systems could be effectively evaluated during development and preproduction and after first production units were built. A primary requirement was that this system remain flexible with respect to configuration and mission and that it be easily maintainable. In addition, the system must be upgraded easily as old product requirements and definitions are replaced by new designs. As a result of this study it is concluded that this project would involve the expenditure of considerable funds and manpower at the beginning of the project and that the cost effectiveness of the system would be dependent upon its utilization and management. This study also demonstrates how the use of computer interface hardware standards (IEEE 583) can minimize requirements for expensive specially designed test equipment for each application.

  2. Signals and systems laboratory with Matlab

    CERN Document Server

    Palamides, Alex

    2010-01-01

    Introduction to MATLAB®Working EnvironmentGetting StartedMemory ManagementVectorsMatricesPlotting with MATLABComplex NumbersM-FilesInput-Output CommandsFile ManagementLogical-Relational OperatorsControl FlowSymbolic VariablesPolynomials(Pseudo)Random NumbersSignalsCategorization by the Variable TypeBasic Continuous-Time SignalsDiscrete-Time SignalsProperties of SignalsTransformations of the Time Variable for Continuous-Time SignalsTransformations of the Time Variable for Discrete-Time SignalsSystemsSystems ClassificationProperties of SystemsTime Domain System AnalysisImpulse ResponseContinuous Time Convolution Convolution PropertiesInterconnections of SystemsStabilityDiscrete-Time ConvolutionSystems Described by Difference EquationsFiltersStability Criterion for Discrete-Time SystemsSystems Described by Differential EquationsStep Response of a SystemFourier SeriesOrthogonality of Complex Exponential SignalsComplex Exponential Fourier SeriesTrigonometric Fourier SeriesFourier Series in the Cosine with Phase F...

  3. Challenges in small screening laboratories: implementing an on-demand laboratory information management system.

    Science.gov (United States)

    Lemmon, Vance P; Jia, Yuanyuan; Shi, Yan; Holbrook, S Douglas; Bixby, John L; Buchser, William

    2011-11-01

    The Miami Project to Cure Paralysis, part of the University of Miami Miller School of Medicine, includes a laboratory devoted to High Content Analysis (HCA) of neurons. The goal of the laboratory is to uncover signaling pathways, genes, compounds, or drugs that can be used to promote nerve growth. HCA permits the quantification of neuronal morphology, including the lengths and numbers of axons. HCA of various libraries on primary neurons requires a team-based approach, a variety of process steps and complex manipulations of cells and libraries to obtain meaningful results. HCA itself produces vast amounts of information including images, well-based data and cell-based phenotypic measures. Documenting and integrating the experimental workflows, library data and extensive experimental results is challenging. For academic laboratories generating large data sets from experiments involving thousands of perturbagens, a Laboratory Information Management System (LIMS) is the data tracking solution of choice. With both productivity and efficiency as driving rationales, the Miami Project has equipped its HCA laboratory with an On Demand or Software As A Service (SaaS) LIMS to ensure the quality of its experiments and workflows. The article discusses how the system was selected and integrated into the laboratory. The advantages of a SaaS based LIMS over a client-server based system are described. © 2011 Bentham Science Publishers

  4. Design of a velocity and position control laboratory servo system

    Science.gov (United States)

    Ziegler, Michael A.

    1987-09-01

    In support of a course in automatic control theory, a velocity and position control laboratory servo system was designed for use in laboratory exercises. The system is constructed using a commercially available DC motor and power amplifier, which are interfaced to a student control panel. All system changes and measurements are conducted with the control panel. The system can be operated open or closed loop, in a position or velocity control mode, and has several adjustable compensators incorporated in the signal path. This thesis provides detailed construction, wiring, and system testing steps, along with the required scale drawings, necessary to perform the hardware integration. A set of laboratory procedures, example laboratory reports, and advanced servo control problems are included for instructional purposes.

  5. Laboratory testing of the vestibular system.

    Science.gov (United States)

    Clarke, Andrew H

    2010-10-01

    Recent reports on vestibular testing, relevant to clinical diagnosis, are reviewed.Besides the case history and bedside examination, objective measurement of the vestibuloocular reflex in all of its facets remains the cornerstone in the diagnostic process. In recent years, this has been enhanced considerably by reliable unilateral tests for the otolith organs, most notably by vestibular-evoked myogenic potential recording and estimation of subjective visual vertical. In addition, progress has been made in the investigation of multisensory interaction, involving visual acuity and posturography.Technological developments include improved eye movement measurement techniques, electrotactile and vibrotactile sensory enhancement or substitution, the use of virtual reality devices and motion stimulators such as hexapods and the rediscovery of galvanic vestibular stimulation as a research and diagnostic tool. The recent introduction of new tests, together with the development of novel technologies, is gradually increasing the scope of the physical and bedside examination of the dizzy patient (see chapter 'Medical management of peripheral disorders' in this issue). The use of more complex equipment, such as rotating chairs, linear sleds, hexapods and posturography platforms, is likely to become limited to specialized laboratories and rehabilitation centers in future years. Further, high resolution magnetic resonance tomography (MRT) and computed tomography have allowed insight into the morphology and determination of malformations of the human labyrinth.

  6. 78 FR 60245 - Privacy Act Systems of Records; LabWare Laboratory Information Management System

    Science.gov (United States)

    2013-10-01

    ... Office of the Secretary Privacy Act Systems of Records; LabWare Laboratory Information Management System... is the LabWare Laboratory Information Management System, USDA-APHIS-19. This notice is necessary to... (USDA) is proposing to add a new system of records, entitled LabWare Laboratory Information Management...

  7. DEMONSTRATION BULLETIN: IN SITU ELECTROKINETIC EXTRACTION SYSTEM - SANDIA NATIONAL LABORATORIES

    Science.gov (United States)

    Sandia National Laboratories (SNL) has developed an in situ soil remediation system that uses electrokinetic principles to remediate hexavalent chromium-contaminated unsaturated or partially saturated soils. The technology involves the in situ application of direct current to the...

  8. Earth System Research Laboratory Long-Term Surface Aerosol Measurements

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Aerosol measurements began at the NOAA Earth System Research Laboratory (ESRL) Global Monitoring Division (GMD) baseline observatories in the mid-1970's with the...

  9. The aerospace energy systems laboratory: Hardware and software implementation

    Science.gov (United States)

    Glover, Richard D.; Oneil-Rood, Nora

    1989-01-01

    For many years NASA Ames Research Center, Dryden Flight Research Facility has employed automation in the servicing of flight critical aircraft batteries. Recently a major upgrade to Dryden's computerized Battery Systems Laboratory was initiated to incorporate distributed processing and a centralized database. The new facility, called the Aerospace Energy Systems Laboratory (AESL), is being mechanized with iAPX86 and iAPX286 hardware running iRMX86. The hardware configuration and software structure for the AESL are described.

  10. Laboratory information management system chain of custody: reliability and security.

    Science.gov (United States)

    Tomlinson, J J; Elliott-Smith, W; Radosta, T

    2006-01-01

    A chain of custody (COC) is required in many laboratories that handle forensics, drugs of abuse, environmental, clinical, and DNA testing, as well as other laboratories that want to assure reliability of reported results. Maintaining a dependable COC can be laborious, but with the recent establishment of the criteria for electronic records and signatures by US regulatory agencies, laboratory information management systems (LIMSs) are now being developed to fully automate COCs. The extent of automation and of data reliability can vary, and FDA- and EPA-compliant electronic signatures and system security are rare.

  11. Laboratory Information Management System (LIMS): A case study

    Science.gov (United States)

    Crandall, Karen S.; Auping, Judith V.; Megargle, Robert G.

    1987-01-01

    In the late 70's, a refurbishment of the analytical laboratories serving the Materials Division at NASA Lewis Research Center was undertaken. As part of the modernization efforts, a Laboratory Information Management System (LIMS) was to be included. Preliminary studies indicated a custom-designed system as the best choice in order to satisfy all of the requirements. A scaled down version of the original design has been in operation since 1984. The LIMS, a combination of computer hardware, provides the chemical characterization laboratory with an information data base, a report generator, a user interface, and networking capabilities. This paper is an account of the processes involved in designing and implementing that LIMS.

  12. Laboratory Information Management System Chain of Custody: Reliability and Security

    Science.gov (United States)

    Tomlinson, J. J.; Elliott-Smith, W.; Radosta, T.

    2006-01-01

    A chain of custody (COC) is required in many laboratories that handle forensics, drugs of abuse, environmental, clinical, and DNA testing, as well as other laboratories that want to assure reliability of reported results. Maintaining a dependable COC can be laborious, but with the recent establishment of the criteria for electronic records and signatures by US regulatory agencies, laboratory information management systems (LIMSs) are now being developed to fully automate COCs. The extent of automation and of data reliability can vary, and FDA- and EPA-compliant electronic signatures and system security are rare. PMID:17671623

  13. Laboratory system strengthening and quality improvement in Ethiopia

    Directory of Open Access Journals (Sweden)

    Tilahun M. Hiwotu

    2014-09-01

    Full Text Available Background: In 2010, a National Laboratory Strategic Plan was set forth in Ethiopia to strengthen laboratory quality systems and set the stage for laboratory accreditation. As a result, the Strengthening Laboratory Management Toward Accreditation (SLMTA programme was initiated in 45 Ethiopian laboratories.Objectives: This article discusses the implementation of the programme, the findings from the evaluation process and key challenges.Methods: The 45 laboratories were divided into two consecutive cohorts and staff from each laboratory participated in SLMTA training and improvement projects. The average amount of supportive supervision conducted in the laboratories was 68 hours for cohort I and two hoursfor cohort II. Baseline and exit audits were conducted in 44 of the laboratories and percent compliance was determined using a checklist with scores divided into zero- to five-star ratinglevels.Results: Improvements, ranging from < 1 to 51 percentage points, were noted in 42 laboratories, whilst decreases were recorded in two. The average scores at the baseline and exit audits were 40% and 58% for cohort I (p < 0.01; and 42% and 53% for cohort II (p < 0.01,respectively. The p-value for difference between cohorts was 0.07. At the exit audit, 61% ofthe first and 48% of the second cohort laboratories achieved an increase in star rating. Poor awareness, lack of harmonisation with other facility activities and the absence of a quality manual were challenges identified.Conclusion: Improvements resulting from SLMTA implementation are encouraging. Continuous advocacy at all levels of the health system is needed to ensure involvement of stakeholders and integration with other improvement initiatives and routine activities.

  14. Laboratory system strengthening and quality improvement in Ethiopia

    Directory of Open Access Journals (Sweden)

    Tilahun M. Hiwotu

    2014-11-01

    Full Text Available Background: In 2010, a National Laboratory Strategic Plan was set forth in Ethiopia to strengthen laboratory quality systems and set the stage for laboratory accreditation. As a result, the Strengthening Laboratory Management Toward Accreditation (SLMTA programme was initiated in 45 Ethiopian laboratories. Objectives: This article discusses the implementation of the programme, the findings from the evaluation process and key challenges. Methods: The 45 laboratories were divided into two consecutive cohorts and staff from each laboratory participated in SLMTA training and improvement projects. The average amount of supportive supervision conducted in the laboratories was 68 hours for cohort I and two hoursfor cohort II. Baseline and exit audits were conducted in 44 of the laboratories and percent compliance was determined using a checklist with scores divided into zero- to five-star ratinglevels. Results: Improvements, ranging from < 1 to 51 percentage points, were noted in 42 laboratories, whilst decreases were recorded in two. The average scores at the baseline and exit audits were 40% and 58% for cohort I (p < 0.01; and 42% and 53% for cohort II (p < 0.01,respectively. The p-value for difference between cohorts was 0.07. At the exit audit, 61% ofthe first and 48% of the second cohort laboratories achieved an increase in star rating. Poor awareness, lack of harmonisation with other facility activities and the absence of a quality manual were challenges identified. Conclusion: Improvements resulting from SLMTA implementation are encouraging. Continuous advocacy at all levels of the health system is needed to ensure involvement of stakeholders and integration with other improvement initiatives and routine activities.

  15. Potential of Laboratory Execution Systems (LESs) to Simplify the Application of Business Process Management Systems (BPMSs) in Laboratory Automation.

    Science.gov (United States)

    Neubert, Sebastian; Göde, Bernd; Gu, Xiangyu; Stoll, Norbert; Thurow, Kerstin

    2017-04-01

    Modern business process management (BPM) is increasingly interesting for laboratory automation. End-to-end workflow automation and improved top-level systems integration for information technology (IT) and automation systems are especially prominent objectives. With the ISO Standard Business Process Model and Notation (BPMN) 2.X, a system-independent and interdisciplinary accepted graphical process control notation is provided, allowing process analysis, while also being executable. The transfer of BPM solutions to structured laboratory automation places novel demands, for example, concerning the real-time-critical process and systems integration. The article discusses the potential of laboratory execution systems (LESs) for an easier implementation of the business process management system (BPMS) in hierarchical laboratory automation. In particular, complex application scenarios, including long process chains based on, for example, several distributed automation islands and mobile laboratory robots for a material transport, are difficult to handle in BPMSs. The presented approach deals with the displacement of workflow control tasks into life science specialized LESs, the reduction of numerous different interfaces between BPMSs and subsystems, and the simplification of complex process modelings. Thus, the integration effort for complex laboratory workflows can be significantly reduced for strictly structured automation solutions. An example application, consisting of a mixture of manual and automated subprocesses, is demonstrated by the presented BPMS-LES approach.

  16. Information systems as a quality management tool in clinical laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Schmitz, Vanessa; Boukhari, Marta Rosecler Bez el [Centro Universitario Feevale, Novo Hamburgo/RS (Brazil)

    2007-11-15

    This article describes information systems as a quality management tool in clinical laboratories. The quality of laboratory analyses is of fundamental importance for health professionals in aiding appropriate diagnosis and treatment. Information systems allow the automation of internal quality management processes, using standard sample tests, Levey-Jennings charts and Westgard multirule analysis. This simplifies evaluation and interpretation of quality tests and reduces the possibility of human error. This study proposes the development of an information system with appropriate functions and costs for the automation of internal quality control in small and medium-sized clinical laboratories. To this end, it evaluates the functions and usability of two commercial software products designed for this purpose, identifying the positive features of each, so that these can be taken into account during the development of the proposed system.

  17. Information systems as a quality management tool in clinical laboratories

    Science.gov (United States)

    Schmitz, Vanessa; Rosecler Bez el Boukhari, Marta

    2007-11-01

    This article describes information systems as a quality management tool in clinical laboratories. The quality of laboratory analyses is of fundamental importance for health professionals in aiding appropriate diagnosis and treatment. Information systems allow the automation of internal quality management processes, using standard sample tests, Levey-Jennings charts and Westgard multirule analysis. This simplifies evaluation and interpretation of quality tests and reduces the possibility of human error. This study proposes the development of an information system with appropriate functions and costs for the automation of internal quality control in small and medium-sized clinical laboratories. To this end, it evaluates the functions and usability of two commercial software products designed for this purpose, identifying the positive features of each, so that these can be taken into account during the development of the proposed system.

  18. Automatic rendezvous system testing at the Flight Robotics Laboratory

    Science.gov (United States)

    Tobbe, Patrick A.; Naumann, Charles B.

    1991-01-01

    The Flight Robotics Laboratory of MSFC provides sophisticated real time simulation capability in the study of human/system interactions of remote systems. This paper will describe the Flight Robotics Facility of NASA/MSFC, the hardware-in-the-loop simulation configuration, and test results.

  19. Sandia National Laboratories, California Environmental Management System program manual.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2013-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 436.1.

  20. Sandia National Laboratories, California Environmental Management System program manual

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2014-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 436.1.

  1. Integrated management system best practices in radioecological laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Claudia Aparecida Zerbinatti de [Centro Tecnologico da Marinha em Sao Paulo (CTMSP), SP (Brazil). Dept. da Qualidade], e-mail: clau.zerbina@gmail.com; Zouain, Desiree Moraes [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)], e-mail: dmzouain@ipen.br

    2009-07-01

    This paper presents a Master dissertation advancements with the target of studying the best practices, in order to give support to an IMS conceptual model ?Integrated Management System (quality, environment, work safety and health), applied to radioecological laboratories. The planning of the proposed research comprises the following stages: first stage - the bibliographic and documental survey in IMS; a survey and study of the applied standards (QMS NBR ISO 9000 (2005), NBR ISO 9001 (2008), NBR ISO 9004 (2000), EMS 14001(2004) and OHSMS OHSAS 18001 (2007) and OHSAS 18002 (2008)); identification and characterization in radioecological laboratories processes; a methodological study of better practices and benchmarking is carried out. In the second stage of the research, the development of a case study is forecast (qualitative research, with electronic questionnaires and personal interviews, when possible), preceded by a survey and selection of international and national radioecological laboratories to be studied and, in sequence, these laboratories should be contacted and agree to participate in the research; in a third stage, the construction of a matrix of better practices, which incur in the results able to subside an IMS conceptual model proposition for radioecological laboratories; the fourth and last stage of the research comprises the construction of a conceptual proposal of an IMS structure for radioecological laboratories. The first stage of the research results are presented concisely, as well as a preliminary selection of laboratories to be studied. (author)

  2. Installation of Computerized Procedure System and Advanced Alarm System in the Human Systems Simulation Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Le Blanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States); Spielman, Zachary Alexander [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rice, Brandon Charles [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-04-01

    This report describes the installation of two advanced control room technologies, an advanced alarm system and a computerized procedure system, into the Human Systems Simulation Laboratory (HSSL). Installation of these technologies enables future phases of this research by providing a platform to systematically evaluate the effect of these technologies on operator and plant performance.

  3. Laboratory Information System – Where are we Today?

    Directory of Open Access Journals (Sweden)

    Lukić Vera

    2017-09-01

    Full Text Available Wider implementation of laboratory information systems (LIS in clinical laboratories in Serbia has been initiated ten years ago. The first LIS in the Railway Health Care Institute has been implemented nine years ago. Before the LIS was initiated, manual admission procedures limited daily output of patients. Moreover, manual entering of patients data and ordering tests on analyzers was problematic and time consuming. After completing tests, laboratory personnel had to write results in patient register (with potential errors and provide invoices for health insurance organisation. First LIS brought forward some advantages with regards to these obstacles, but it also showed various weaknesses. These can be summarised in rigidity of system and inability to fulfil user expectation. After 4 years of use, we replaced this system with another LIS. Hence, the main aim of this paper is to evaluate advant ages of using LIS in laboratory of the Railway Health Care Institute and also to discuss further possibilities for its application. After implementing LIS, admission procedure has proven to be much faster. LIS enabled electronic requests, barcoded specimens prevent identification errors, bidirectional interface replaces redundant data entry steps, QC data are transferred automatically, results are electronically validated and automatically archived in data base, billing information is transferred electronically, and more. We also use some advanced options, like delta check, HIL feature, quality indicators and various types of reports. All steps in total testing process are drastically improved after the implementation of LIS, which had a positive impact on the quality of issued laboratory results. However, we expect development of some new features in the future, for example auto-verification and inventory management. On the example of the laboratory of the Railway Health Care Institute, we show that it is crucial that laboratory specialists have the main

  4. Laboratory Information Management Systems for Forensic Laboratories: A White Paper for Directors and Decision Makers

    Energy Technology Data Exchange (ETDEWEB)

    Anthony Hendrickson; Brian Mennecke; Kevin Scheibe; Anthony Townsend

    2005-10-01

    Modern, forensics laboratories need Laboratory Information Management Systems (LIMS) implementations that allow the lab to track evidentiary items through their examination lifecycle and also serve all pertinent laboratory personnel. The research presented here presents LIMS core requirements as viewed by respondents serving in different forensic laboratory capacities as well as different forensic laboratory environments. A product-development methodology was employed to evaluate the relative value of the key features that constitute a LIMS, in order to develop a set of relative values for these features and the specifics of their implementation. In addition to the results of the product development analysis, this paper also provides an extensive review of LIMS and provides an overview of the preparation and planning process for the successful upgrade or implementation of a LIMS. Analysis of the data indicate that the relative value of LIMS components are viewed differently depending upon respondents' job roles (i.e., evidence technicians, scientists, and lab management), as well as by laboratory size. Specifically, the data show that: (1) Evidence technicians place the most value on chain of evidence capabilities and on chain of custody tracking; (2) Scientists generally place greatest value on report writing and generation, and on tracking daughter evidence that develops during their analyses; (3) Lab. Managers place the greatest value on chain of custody, daughter evidence, and not surprisingly, management reporting capabilities; and (4) Lab size affects LIMS preference in that, while all labs place daughter evidence tracking, chain of custody, and management and analyst report generation as their top three priorities, the order of this prioritization is size dependent.

  5. Pilot system development in metre-scale laboratory discharge

    OpenAIRE

    Kochkin, Pavlo; Lehtinen, Nikolai; Alexander,; van Deursen, P. J.; Østgaard, Nikolai

    2017-01-01

    The pilot system development in metre-scale negative laboratory discharges is studied with ns-fast photography. The systems appear as bipolar structures in the vicinity of the negative high-voltage electrode. They appear as a result of a single negative streamer propagation and determine further discharge development. Such systems possess features like glowing beads, bipolarity, different brightness of the top and bottom parts, and mutual reconnection. A 1D model of the ionization evolution i...

  6. Accreditation of Medical LaboratoriesSystem, Process, Benefits for Labs

    Directory of Open Access Journals (Sweden)

    Zima Tomáš

    2017-09-01

    Full Text Available One and key of the priorities in laboratory medicine is improvement of quality management system for patient safety. Quality in the health care is tightly connected to the level of excellence of the health care provided in relation to the current level of knowledge and technical development. Accreditation is an effective way to demonstrate competence of the laboratory, a tool to recognize laboratories world-wide, is linked to periodical audits, to stimulate the maintenance and improvement of the quality, which leads to high standard of services for clients (patients, health care providers, etc.. The strategic plans of IFCC and EFLM include focusing on accreditation of labs based on ISO standards and cooperation with European Accreditation and national accreditation bodies. IFCC and EFLM recognised that ISO 15189:2012 Medical laboratories – Requirements for quality and competence, encompasses all the assessment criteria specified in the policy of quality. The last version is oriented to process approach with detailed division and clearly defined requirements. The accreditation of labs improves facilitation of accurate and rapid diagnostics, efficiency of treatment and reduction of errors in the laboratory process. Accreditation is not about who the best is, but who has a system of standard procedures with aim to improve the quality and patient safety. Quality system is about people, with people and for people.

  7. Building a Laboratory Information Management System Using Windows4GL

    Energy Technology Data Exchange (ETDEWEB)

    Pickens, M.A.; Shaieb, M.R.

    1996-05-01

    The system discussed is currently implemented at LLNL in the Environmental Services program which operates out of the Chemistry & Materials Science (C&MS) directorate. Responsibility is to provide the C&MS Environmental Services (CES) program with an enterprise-wide information system which will aid CES. The specific portion of the information system is the Sample Tracking, Analysis and Reporting System (STARS). Since CES was formed by merging two analytical laboratory organizations in May 1995, a new Laboratory Information Management System (LIMS) had to be developed. The development of a LIMS in Windows4GL was found to be satisfactory. The product STARS was well received by the user community, and it has improved business practices and efficiency in CES. The CES management staff has seen increased personnel productivity since STARS was release. We look forward to upgrading to CA-OpenROAD and taking advantage of its many improved and innovative features to further enhance STARS.

  8. System Quality Management in Software Testing Laboratory that Chooses Accreditation

    Directory of Open Access Journals (Sweden)

    Yanet Brito R.

    2013-12-01

    Full Text Available The evaluation of software products will reach full maturity when executed by the scheme and provides third party certification. For the validity of the certification, the independent laboratory must be accredited for that function, using internationally recognized standards. This brings with it a challenge for the Industrial Laboratory Testing Software (LIPS, responsible for testing the products developed in Cuban Software Industry, define strategies that will permit it to offer services with a high level of quality. Therefore it is necessary to establish a system of quality management according to NC-ISO/IEC 17025: 2006 to continuously improve the operational capacity and technical competence of the laboratory, with a view to future accreditation of tests performed. This article discusses the process defined in the LIPS for the implementation of a Management System of Quality, from the current standards and trends, as a necessary step to opt for the accreditation of the tests performed.

  9. AUTOMATED REMOTE MANAGEMENT AND CONTROL SYSTEM OF THE LABORATORY EQUIPMENT

    Directory of Open Access Journals (Sweden)

    V. I. Freyman

    2017-01-01

    Full Text Available The paper deals with the hardware and software implementation of automated remote management system of laboratory equipment for studying fundamentals of electronics and circuit technology. This system gives the possibility to create the virtual model of a real stand. The original software has enabled to compare information from the memory of microcontroller keeping in laboratory stands with etalon model, and reveal discrepancies of set connections and template data. Graphical interface allows for operation control of students and correction of studying process. Automation of configuring and the following checking procedures has accelerated the work and decreased error frequency, made it possible to improve the quality of learning, increase efficiency of laboratory researches and control accuracy, intensify the check procedure and use self-checking in case of independent execution of tasks.

  10. A laboratory goniometer system for measuring reflectance and emittance anisotropy

    NARCIS (Netherlands)

    Roosjen, P.P.J.; Clevers, J.G.P.W.; Bartholomeus, H.; Schaepman, M.E.; Schaepman-Strub, G.; Jalink, H.; Schoor, van der R.; Jong, de A.

    2012-01-01

    In this paper, a laboratory goniometer system for performing multi-angular measurements under controlled illumination conditions is described. A commercially available robotic arm enables the acquisition of a large number of measurements over the full hemisphere within a short time span making it

  11. A laboratory information management system for DNA barcoding workflows

    NARCIS (Netherlands)

    Vu, D.; Eberhardt, U.; Szöke, S.; Groenewald, M.; Robert, V.

    2012-01-01

    This paper presents a laboratory information management system for DNA sequences (LIMS) created and based on the needs of a DNA barcoding project at the CBS-KNAW Fungal Biodiversity Centre (Utrecht, the Netherlands). DNA barcoding is a global initiative for species identification through simple DNA

  12. A Reverse Osmosis System for an Advanced Separation Process Laboratory.

    Science.gov (United States)

    Slater, C. S.; Paccione, J. D.

    1987-01-01

    Focuses on the development of a pilot unit for use in an advanced separations process laboratory in an effort to develop experiments on such processes as reverse osmosis, ultrafiltration, adsorption, and chromatography. Discusses reverse osmosis principles, the experimental system design, and some experimental studies. (TW)

  13. Laboratory evaluation of Fecker and Loral optical IR PWI systems

    Science.gov (United States)

    Gorstein, M.; Hallock, J. N.; Houten, M.; Mcwilliams, I. G.

    1971-01-01

    A previous flight test of two electro-optical pilot warning indicators, using a flashing xenon strobe and silicon detectors as cooperative elements, pointed out several design deficiencies. The present laboratory evaluation program corrected these faults and calibrated the sensitivity of both systems in azimuth elevation and range. The laboratory tests were performed on an optical bench and consisted of three basic components: (1) a xenon strobe lamp whose output is monitored at the indicator detector to give pulse to pulse information on energy content at the receiver; (2) a strobe light attenuating optical system which is calibrated photometrically to provide simulated range; and (3) a positioning table on which the indicator system under study is mounted and which provides spatial location coordinates for all data points. The test results for both systems are tabulated.

  14. Improving quality management systems of laboratories in developing countries: an innovative training approach to accelerate laboratory accreditation.

    Science.gov (United States)

    Yao, Katy; McKinney, Barbara; Murphy, Anna; Rotz, Phil; Wafula, Winnie; Sendagire, Hakim; Okui, Scolastica; Nkengasong, John N

    2010-09-01

    The Strengthening Laboratory Management Toward Accreditation (SLMTA) program was developed to promote immediate, measurable improvement in laboratories of developing countries. The laboratory management framework, a tool that prescribes managerial job tasks, forms the basis of the hands-on, activity-based curriculum. SLMTA is implemented through multiple workshops with intervening site visits to support improvement projects. To evaluate the effectiveness of SLMTA, the laboratory accreditation checklist was developed and subsequently adopted by the World Health Organization Regional Office for Africa (WHO AFRO). The SLMTA program and the implementation model were validated through a pilot in Uganda. SLMTA yielded observable, measurable results in the laboratories and improved patient flow and turnaround time in a laboratory simulation. The laboratory staff members were empowered to improve their own laboratories by using existing resources, communicate with clinicians and hospital administrators, and advocate for system strengthening. The SLMTA program supports laboratories by improving management and building preparedness for accreditation.

  15. Onsite Distributed Generation Systems For Laboratories, Laboratories for the 21st Century: Best Practices (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2011-09-01

    This guide provides general information on implementing onsite distributed generation systems in laboratory environments. Specific technology applications, general performance information, and cost data are provided to educate and encourage laboratory energy managers to consider onsite power generation or combined heat and power (CHP) systems for their facilities. After conducting an initial screening, energy managers are encouraged to conduct a detailed feasibility study with actual cost and performance data for technologies that look promising. Onsite distributed generation systems are small, modular, decentralized, grid-connected, or off-grid energy systems. These systems are located at or near the place where the energy is used. These systems are also known as distributed energy or distributed power systems. DG technologies are generally considered those that produce less than 20 megawatts (MW) of power. A number of technologies can be applied as effective onsite DG systems, including: (1) Diesel, natural gas, and dual-fuel reciprocating engines; (2) Combustion turbines and steam turbines; (3) Fuel cells; (4) Biomass heating; (5) Biomass combined heat and power; (6) Photovoltaics; and (7) Wind turbines. These systems can provide a number of potential benefits to an individual laboratory facility or campus, including: (1) High-quality, reliable, and potentially dispatchable power; (2) Low-cost energy and long-term utility cost assurance, especially where electricity and/or fuel costs are high; (3) Significantly reduced greenhouse gas (GHG) emissions. Typical CHP plants reduce onsite GHG by 40 to 60 percent; (4) Peak demand shaving where demand costs are high; (5) CHP where thermal energy can be used in addition to electricity; (6) The ability to meet standby power needs, especially where utility-supplied power is interrupted frequently or for long periods and where standby power is required for safety or emergencies; and (7) Use for standalone or off

  16. Experiential learning in control systems laboratories and engineering project management

    Science.gov (United States)

    Reck, Rebecca Marie

    Experiential learning is a process by which a student creates knowledge through the insights gained from an experience. Kolb's model of experiential learning is a cycle of four modes: (1) concrete experience, (2) reflective observation, (3) abstract conceptualization, and (4) active experimentation. His model is used in each of the three studies presented in this dissertation. Laboratories are a popular way to apply the experiential learning modes in STEM courses. Laboratory kits allow students to take home laboratory equipment to complete experiments on their own time. Although students like laboratory kits, no previous studies compared student learning outcomes on assignments using laboratory kits with existing laboratory equipment. In this study, we examined the similarities and differences between the experiences of students who used a portable laboratory kit and students who used the traditional equipment. During the 2014- 2015 academic year, we conducted a quasi-experiment to compare students' achievement of learning outcomes and their experiences in the instructional laboratory for an introductory control systems course. Half of the laboratory sections in each semester used the existing equipment, while the other sections used a new kit. We collected both quantitative data and qualitative data. We did not identify any major differences in the student experience based on the equipment they used. Course objectives, like research objectives and product requirements, help provide clarity and direction for faculty and students. Unfortunately, course and laboratory objectives are not always clearly stated. Without a clear set of objectives, it can be hard to design a learning experience and determine whether students are achieving the intended outcomes of the course or laboratory. In this study, I identified a common set of laboratory objectives, concepts, and components of a laboratory apparatus for undergraduate control systems laboratories. During the summer of

  17. Retrofitting Combined Space and Water Heating Systems: Laboratory Tests

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, B.; Bohac, D.; Huelman, P.; Olson, R.; Hewitt, M.

    2012-10-01

    Better insulated and tighter homes can often use a single heating plant for both space and domestic water heating. These systems, called dual integrated appliances (DIA) or combination systems, can operate at high efficiency and eliminate combustion safety issues associated by using a condensing, sealed combustion heating plant. Funds were received to install 400 DIAs in Minnesota low-income homes. The NorthernSTAR DIA laboratory was created to identify proper system components, designs, operating parameters, and installation procedures to assure high efficiency of field installed systems. Tests verified that heating loads up to 57,000 Btu/hr can be achieved with acceptable return water temperatures and supply air temperatures.

  18. Using the Human Systems Simulation Laboratory at Idaho National Laboratory for Safety Focused Research

    Energy Technology Data Exchange (ETDEWEB)

    Joe, Jeffrey .C; Boring, Ronald L.

    2016-07-01

    Under the United States (U.S.) Department of Energy (DOE) Light Water Reactor Sustainability (LWRS) program, researchers at Idaho National Laboratory (INL) have been using the Human Systems Simulation Laboratory (HSSL) to conduct critical safety focused Human Factors research and development (R&D) for the nuclear industry. The LWRS program has the overall objective to develop the scientific basis to extend existing nuclear power plant (NPP) operating life beyond the current 60-year licensing period and to ensure their long-term reliability, productivity, safety, and security. One focus area for LWRS is the NPP main control room (MCR), because many of the instrumentation and control (I&C) system technologies installed in the MCR, while highly reliable and safe, are now difficult to replace and are therefore limiting the operating life of the NPP. This paper describes how INL researchers use the HSSL to conduct Human Factors R&D on modernizing or upgrading these I&C systems in a step-wise manner, and how the HSSL has addressed a significant gap in how to upgrade systems and technologies that are built to last, and therefore require careful integration of analog and new advanced digital technologies.

  19. Laboratory quality management system: Road to accreditation and beyond

    Directory of Open Access Journals (Sweden)

    V Wadhwa

    2012-01-01

    Full Text Available This review attempts to clarify the concepts of Laboratory Quality Management System (Lab QMS for a medical testing and diagnostic laboratory in a holistic way and hopes to expand the horizon beyond quality control (QC and quality assurance. It provides an insight on accreditation bodies and highlights a glimpse of existing laboratory practices but essentially it takes the reader through the journey of accreditation and during the course of reading and understanding this document, prepares the laboratory for the same. Some of the areas which have not been highlighted previously include: requirement for accreditation consultants, laboratory infrastructure and scope, applying for accreditation, document preparation. This section is well supported with practical illustrations and necessary tables and exhaustive details like preparation of a standard operating procedure and a quality manual. Concept of training and privileging of staff has been clarified and a few of the QC exercises have been dealt with in a novel way. Finally, a practical advice for facing an actual third party assessment and caution needed to prevent post-assessment pitfalls has been dealt with.

  20. Laboratory quality management system: road to accreditation and beyond.

    Science.gov (United States)

    Wadhwa, V; Rai, S; Thukral, T; Chopra, M

    2012-01-01

    This review attempts to clarify the concepts of Laboratory Quality Management System (Lab QMS) for a medical testing and diagnostic laboratory in a holistic way and hopes to expand the horizon beyond quality control (QC) and quality assurance. It provides an insight on accreditation bodies and highlights a glimpse of existing laboratory practices but essentially it takes the reader through the journey of accreditation and during the course of reading and understanding this document, prepares the laboratory for the same. Some of the areas which have not been highlighted previously include: requirement for accreditation consultants, laboratory infrastructure and scope, applying for accreditation, document preparation. This section is well supported with practical illustrations and necessary tables and exhaustive details like preparation of a standard operating procedure and a quality manual. Concept of training and privileging of staff has been clarified and a few of the QC exercises have been dealt with in a novel way. Finally, a practical advice for facing an actual third party assessment and caution needed to prevent post-assessment pitfalls has been dealt with.

  1. Customizing Laboratory Information Systems: Closing the Functionality Gap.

    Science.gov (United States)

    Gershkovich, Peter; Sinard, John H

    2015-09-01

    Highly customizable laboratory information systems help to address great variations in laboratory workflows, typical in Pathology. Often, however, built-in customization tools are not sufficient to add all of the desired functionality and improve systems interoperability. Emerging technologies and advances in medicine often create a void in functionality that we call a functionality gap. These gaps have distinct characteristics—a persuasive need to change the way a pathology group operates, the general availability of technology to address the missing functionality, the absence of this technology from your laboratory information system, and inability of built-in customization tools to address it. We emphasize the pervasive nature of these gaps, the role of pathology informatics in closing them, and suggest methods on how to achieve that. We found that a large number of the papers in the Journal of Pathology Informatics are concerned with these functionality gaps, and an even larger proportion of electronic posters and abstracts presented at the Pathology Informatics Summit conference each year deal directly with these unmet needs in pathology practice. A rapid, continuous, and sustainable approach to closing these gaps is critical for Pathology to provide the highest quality of care, adopt new technologies, and meet regulatory and financial challenges. The key element of successfully addressing functionality gaps is gap ownership—the ability to control the entire pathology information infrastructure with access to complementary systems and components. In addition, software developers with detailed domain expertise, equipped with right tools and methodology can effectively address these needs as they emerge.

  2. Laboratory diagnostic methods, system of quality and validation

    Directory of Open Access Journals (Sweden)

    Ašanin Ružica

    2005-01-01

    Full Text Available It is known that laboratory investigations secure safe and reliable results that provide a final confirmation of the quality of work. Ideas, planning, knowledge, skills, experience, and environment, along with good laboratory practice, quality control and reliability of quality, make the area of biological investigations very complex. In recent years, quality control, including the control of work in the laboratory, is based on international standards and is used at that level. The implementation of widely recognized international standards, such as the International Standard ISO/IEC 17025 (1 and the implementing of the quality system series ISO/IEC 9000 (2 have become the imperative on the grounds of which laboratories have a formal, visible and corresponding system of quality. The diagnostic methods that are used must constantly yield results which identify the animal as positive or negative, and the precise status of the animal is determined with a predefined degree of statistical significance. Methods applied on a selected population reduce the risk of obtaining falsely positive or falsely negative results. A condition for this are well conceived and documented methods, with the application of the corresponding reagents, and work with professional and skilled staff. This process requires also a consistent implementation of the most rigorous experimental plans, epidemiological and statistical data and estimations, with constant monitoring of the validity of the applied methods. Such an approach is necessary in order to cut down the number of misconceptions and accidental mistakes, for a referent population of animals on which the validity of a method is tested. Once a valid method is included in daily routine investigations, it is necessary to apply constant monitoring for the purpose of internal quality control, in order adequately to evaluate its reproducibility and reliability. Consequently, it is necessary at least twice yearly to conduct

  3. An experimental study of tether reel system: A laboratory model

    OpenAIRE

    Yoshimura, Shoichi; Okamoto, Osamu; 吉村 庄市; 岡本 修

    1992-01-01

    A laboratory prototype model of a reel system has been made as the first step of an in-house hardware study of the tether system in space. The model is consisted of two main parts, i. e., a Reel Drum Driving (RDD) unit (25 kg weight) and a Power Supply/Signal Processing (PSSP) unit (32 kg weight). The tether (0.8 mm in diameter and 300 m long) consists of a Kevlar fiber core and a nylon fiber jacket. Following the preliminary functional test, a computer-controlled functional test has been car...

  4. A feedback system for reducing excessive laboratory tests.

    Science.gov (United States)

    Studnicki, J; Bradham, D D; Marshburn, J; Foulis, P R; Straumfjord, J V

    1993-01-01

    At the James A. Haley Veterans Hospital in Tampa, Fla, a program has been implemented to reduce the amount of potentially excessive laboratory testing. The major program components are a set of test frequency guidelines and a system of feedback to resident physicians that compares their test ordering patterns against the predetermined guidelines. The guidelines are analyte specific and differentiate between normal and abnormal test values reported during 1-day and 7-day time periods. The feedback process includes both systematic reporting of objective data and individual and group education and counseling sessions related to the appropriate use of laboratory tests. A reduction in the percentage of tests that fell outside the guidelines (outliers) was achieved following implementation of the program.

  5. Application of the Toyota Production System improves core laboratory operations.

    Science.gov (United States)

    Rutledge, Joe; Xu, Min; Simpson, Joanne

    2010-01-01

    To meet the increased clinical demands of our hospital expansion, improve quality, and reduce costs, our tertiary care, pediatric core laboratory used the Toyota Production System lean processing to reorganize our 24-hour, 7 d/wk core laboratory. A 4-month, consultant-driven process removed waste, led to a physical reset of the space to match the work flow, and developed a work cell for our random access analyzers. In addition, visual controls, single piece flow, standard work, and "5S" were instituted. The new design met our goals as reflected by achieving and maintaining improved turnaround time (TAT; mean for creatinine reduced from 54 to 23 minutes) with increased testing volume (20%), monetary savings (4 full-time equivalents), decreased variability in TAT, and better space utilization (25% gain). The project had the unanticipated consequence of eliminating STAT testing because our in-laboratory TAT for routine testing was less than our prior STAT turnaround goal. The viability of this approach is demonstrated by sustained gains and further PDCA (Plan, Do, Check, Act) improvements during the 4 years after completion of the project.

  6. Report on the Acadiana Research Laboratory nuclear microprobe system

    Science.gov (United States)

    Glass, Gary A.; Hollerman, William A.; Hynes, Shelly F.; Fournet, Justin; Bailey, Alan M.; Liao, Changgeng

    2001-07-01

    The Acadiana Research Laboratory of the University of Louisiana at Lafayette provides high energy ion beams for materials research. Major components of the ion beam systems include a National Electrostatics Corporation (NEC) 1.7 MV tandem Pelletron accelerator system with both SNICS and RF ion sources and a Varian CF-4 200 kV implanter. The NEC Pelletron has three operational beamlines that provide a wide range of capabilities for materials modification and analysis, including such techniques as PIXE, PIGE, RBS, RFS, TOF-ERDA and ion implantation. An Oxford Microbeams Ltd. microprobe system was recently declared operational with the attainment of a 1.5 μm×2.0 μm beam spot size. Microprobe techniques presently available include μPIXE, μRBS and scanning transmission ion microscopy (STIM).

  7. User requirements on the future laboratory information systems.

    Science.gov (United States)

    Brender, J; McNair, P

    1996-07-01

    Today numerous information technology solutions exist for the clinical laboratory which operate either as stand-alone functionalities or with ad hoc integration solutions. The OpenLabs (A2028) AIM Project puts emphasis on the design and specification of a framework for the interoperability of existing systems and new advanced services, and consequently concentrates on the issue of integration. The purpose of the OpenLabs open architecture is to serve as a functional solution to this integration. A basic principle for this open architecture is that each of the advanced services shall be able to function individually or in any combination with an existing Laboratory Information System (LIS), and that it shall enable new modular functionalities to be incorporated in a 'plug-and-play' fashion. The synthesis of the main user needs and requirements implies that the future IT solutions: (a) must be highly flexible and maximally customizable--by the users themselves; (b) are based on the concept of open systems, both technically and functionally, which enables modular functionalities from different vendors to co-operate forming a global LIS functionality; (c) are future viable and able to incorporate already installed IT functionalities; (d) support management of failure prevention, of repair, of success, and of change. The establishment of an open architecture implies that a market will develop for modular, scaleable, and cost-effective LIS features without today's dependence on individual manufacturers and hardware/software platforms.

  8. The Binary System Laboratory Activities Based on Students Mental Model

    Science.gov (United States)

    Albaiti, A.; Liliasari, S.; Sumarna, O.; Martoprawiro, M. A.

    2017-09-01

    Generic science skills (GSS) are required to develop student conception in learning binary system. The aim of this research was to know the improvement of students GSS through the binary system labotoratory activities based on their mental model using hypothetical-deductive learning cycle. It was a mixed methods embedded experimental model research design. This research involved 15 students of a university in Papua, Indonesia. Essay test of 7 items was used to analyze the improvement of students GSS. Each items was designed to interconnect macroscopic, sub-microscopic and symbolic levels. Students worksheet was used to explore students mental model during investigation in laboratory. The increase of students GSS could be seen in their N-Gain of each GSS indicators. The results were then analyzed descriptively. Students mental model and GSS have been improved from this study. They were interconnect macroscopic and symbolic levels to explain binary systems phenomena. Furthermore, they reconstructed their mental model with interconnecting the three levels of representation in Physical Chemistry. It necessary to integrate the Physical Chemistry Laboratory into a Physical Chemistry course for effectiveness and efficiency.

  9. Sandia National Laboratories, California Environmental Management System Program Manual.

    Energy Technology Data Exchange (ETDEWEB)

    2009-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 450.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a set of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site received ISO 14001 certification in September 2006. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy Management and Fleet Services Environmental programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has several groups operating at Sandia

  10. Sandia National Laboratories, California Environmental Management System Program Manual.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2011-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004and Department of Energy (DOE) Order 450.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a set of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site received ISO 14001 certification in September 2006. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy Management and Fleet Services programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has several groups operating at Sandia National Laboratories

  11. Sandia National Laboratories, California Environmental Management System program manual.

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, Barbara L.

    2012-03-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004and Department of Energy (DOE) Order 436.1. Sandia National Laboratories, California (SNL/CA) has maintained functional environmental programs to assist with regulatory compliance for more than 30 years. During 2005, these existing programs were rolled into a formal environmental management system (EMS) that expands beyond the traditional compliance focus to managing and improving environmental performance and stewardship practices for all site activities. An EMS is a set of inter-related elements that represent a continuing cycle of planning, implementing, evaluating, and improving processes and actions undertaken to achieve environmental policy and goals. The SNL/CA EMS Program conforms to the International Standard for Environmental Management Systems, ISO 14001:2004 (ISO 2004). The site first received ISO 14001 certification in September 2006 and recertification in 2009. SNL/CA's EMS Program is applicable to the Sandia, Livermore site only. Although SNL/CA operates as one organizational division of the overall Sandia National Laboratories, the EMS Program is site-specific, with site-specific objectives and targets. SNL/CA (Division 8000) benefits from the organizational structure as it provides corporate level policies, procedures, and standards, and established processes that connect to and support elements of the SNL/CA EMS Program. Additionally, SNL/CA's EMS Program benefits from two corporate functional programs (Facilities Energy and Water Resource Management and Fleet Services programs) that maintain responsibility for energy management and fleet services for all Sandia locations. Each EMS element is further enhanced with site-specific processes and standards. Division 8000 has

  12. Quality Management Systems in the Clinical Laboratories in Latin America

    Science.gov (United States)

    2015-01-01

    The implementation of management systems in accordance with standards like ISO 9001:2008 (1,2) in the clinical laboratories has conferred and added value of reliability and therefore a very significant input to patient safety. As we know the ISO 9001:2008 (1) a certification standard, and ISO 15189:2012 (2) an accreditation standard, both, at the time have generated institutional memory where they have been implemented, the transformation of culture focused on correct execution, control and following, evidence needed and the importance of register. PMID:27683495

  13. The Development of A Human Systems Simulation Laboratory: Strategic Direction

    Energy Technology Data Exchange (ETDEWEB)

    Jacques Hugo; Katya le Blanc; David Gertman

    2012-07-01

    The Human System Simulation Laboratory (HSSL) at the Idaho National Laboratory is one of few facilities of its kind that allows human factors researchers to evaluate various aspects of human performance and human system interaction for proposed reactor designs and upgrades. A basic system architecture, physical configuration and simulation capability were established to enable human factors researchers to support multiple, simultaneous simulations and also different power plant technologies. Although still evolving in terms of its technical and functional architecture, the HSSL is already proving its worth in supporting current and future nuclear industry needs for light water reactor sustainability and small modular reactors. The evolution of the HSSL is focused on continual physical and functional refinement to make it a fully equipped, reconfigurable facility where advanced research, testing and validation studies can be conducted on a wider range of reactor technologies. This requires the implementation of additional plant models to produce empirical research data on human performance with emerging human-system interaction technologies. Additional beneficiaries of this information include system designers and HRA practitioners. To ensure that results of control room crew studies will be generalizable to the existing and evolving fleet of US reactors, future expansion of the HSSL may also include other SMR plant models, plant-specific simulators and a generic plant model aligned to the current generation of pressurized water reactors (PWRs) and future advanced reactor designs. Collaboration with industry partners is also proving to be a vital component of the facility as this helps to establish a formal basis for current and future human performance experiments to support nuclear industry objectives. A long-range Program Plan has been developed for the HSSL to ensure that the facility will support not only the Department of Energy’s Light Water Reactor

  14. Digital Audio Radio Broadcast Systems Laboratory Testing Nearly Complete

    Science.gov (United States)

    2005-01-01

    Radio history continues to be made at the NASA Lewis Research Center with the completion of phase one of the digital audio radio (DAR) testing conducted by the Consumer Electronics Group of the Electronic Industries Association. This satellite, satellite/terrestrial, and terrestrial digital technology will open up new audio broadcasting opportunities both domestically and worldwide. It will significantly improve the current quality of amplitude-modulated/frequency-modulated (AM/FM) radio with a new digitally modulated radio signal and will introduce true compact-disc-quality (CD-quality) sound for the first time. Lewis is hosting the laboratory testing of seven proposed digital audio radio systems and modes. Two of the proposed systems operate in two modes each, making a total of nine systems being tested. The nine systems are divided into the following types of transmission: in-band on-channel (IBOC), in-band adjacent-channel (IBAC), and new bands. The laboratory testing was conducted by the Consumer Electronics Group of the Electronic Industries Association. Subjective assessments of the audio recordings for each of the nine systems was conducted by the Communications Research Center in Ottawa, Canada, under contract to the Electronic Industries Association. The Communications Research Center has the only CCIR-qualified (Consultative Committee for International Radio) audio testing facility in North America. The main goals of the U.S. testing process are to (1) provide technical data to the Federal Communication Commission (FCC) so that it can establish a standard for digital audio receivers and transmitters and (2) provide the receiver and transmitter industries with the proper standards upon which to build their equipment. In addition, the data will be forwarded to the International Telecommunications Union to help in the establishment of international standards for digital audio receivers and transmitters, thus allowing U.S. manufacturers to compete in the

  15. A laboratory goniometer system for measuring reflectance and emittance anisotropy.

    Science.gov (United States)

    Roosjen, Peter P J; Clevers, Jan G P W; Bartholomeus, Harm M; Schaepman, Michael E; Schaepman-Strub, Gabriela; Jalink, Henk; van der Schoor, Rob; de Jong, Arjan

    2012-12-13

    In this paper, a laboratory goniometer system for performing multi-angular measurements under controlled illumination conditions is described. A commercially available robotic arm enables the acquisition of a large number of measurements over the full hemisphere within a short time span making it much faster than other goniometers. In addition, the presented set-up enables assessment of anisotropic reflectance and emittance behaviour of soils, leaves and small canopies. Mounting a spectrometer enables acquisition of either hemispherical measurements or measurements in the horizontal plane. Mounting a thermal camera allows directional observations of the thermal emittance. This paper also presents three showcases of these different measurement set-ups in order to illustrate its possibilities. Finally, suggestions for applying this instrument and for future research directions are given, including linking the measured reflectance anisotropy with physically-based anisotropy models on the one hand and combining them with field goniometry measurements for joint analysis with remote sensing data on the other hand. The speed and flexibility of the system offer a large added value to the existing pool of laboratory goniometers.

  16. A laboratory information management system for DNA barcoding workflows.

    Science.gov (United States)

    Vu, Thuy Duong; Eberhardt, Ursula; Szöke, Szániszló; Groenewald, Marizeth; Robert, Vincent

    2012-07-01

    This paper presents a laboratory information management system for DNA sequences (LIMS) created and based on the needs of a DNA barcoding project at the CBS-KNAW Fungal Biodiversity Centre (Utrecht, the Netherlands). DNA barcoding is a global initiative for species identification through simple DNA sequence markers. We aim at generating barcode data for all strains (or specimens) included in the collection (currently ca. 80 k). The LIMS has been developed to better manage large amounts of sequence data and to keep track of the whole experimental procedure. The system has allowed us to classify strains more efficiently as the quality of sequence data has improved, and as a result, up-to-date taxonomic names have been given to strains and more accurate correlation analyses have been carried out.

  17. Validation of a laboratory and hospital information system in a medical laboratory accredited according to ISO 15189.

    Science.gov (United States)

    Biljak, Vanja Radisic; Ozvald, Ivan; Radeljak, Andrea; Majdenic, Kresimir; Lasic, Branka; Siftar, Zoran; Lovrencic, Marijana Vucic; Flegar-Mestric, Zlata

    2012-01-01

    The aim of the study was to present a protocol for laboratory information system (LIS) and hospital information system (HIS) validation at the Institute of Clinical Chemistry and Laboratory Medicine of the Merkur University Hospital, Zagreb, Croatia. Validity of data traceability was checked by entering all test requests for virtual patient into HIS/LIS and printing corresponding barcoded labels that provided laboratory analyzers with the information on requested tests. The original printouts of the test results from laboratory analyzer(s) were compared with the data obtained from LIS and entered into the provided template. Transfer of data from LIS to HIS was examined by requesting all tests in HIS and creating real data in a finding generated in LIS. Data obtained from LIS and HIS were entered into a corresponding template. The main outcome measure was the accuracy of transfer obtained from laboratory analyzers and results transferred from LIS and HIS expressed as percentage (%). The accuracy of data transfer from laboratory analyzers to LIS was 99.5% and of that from LIS to HIS 100%. We presented our established validation protocol for laboratory information system and demonstrated that a system meets its intended purpose.

  18. Integrating a FISH imaging system into the cytology laboratory

    Directory of Open Access Journals (Sweden)

    Denice Smith G

    2010-01-01

    Full Text Available We have implemented an interactive imaging system for the interpretation of UroVysion fluorescence in situ hybridization (FISH to improve throughput, productivity, quality control and diagnostic accuracy. We describe the Duet imaging system, our experiences with implementation, and outline the financial investment, space requirements, information technology needs, validation, and training of cytotechnologists needed to integrate such a system into a cytology laboratory. Before purchasing the imaging system, we evaluated and validated the instrument at our facility. Implementation required slide preparation changes, IT modifications, development of training programs, and revision of job descriptions for cytotechnologists. A darkened room was built to house the automated scanning station and microscope, as well as two imaging stations. IT changes included generation of storage for archival images on the LAN, addition of external hard drives for back-up, and changes to cable connections for communication between remote locations. Training programs for cytotechnologists, and pathologists/fellows/residents were developed, and cytotechnologists were integrated into multiple steps of the process. The imaging system has resulted in increased productivity for pathologists, concomitant with an expanded role of cytotechnologists in multiple critical steps, including FISH, scan setup, reclassification, and initial interpretation.

  19. Integrating a FISH imaging system into the cytology laboratory.

    Science.gov (United States)

    Smith, G Denice; Riding, Matt; Oswald, Kim; Bentz, Joel S

    2010-04-06

    We have implemented an interactive imaging system for the interpretation of UroVysion fluorescence in situ hybridization (FISH) to improve throughput, productivity, quality control and diagnostic accuracy. We describe the Duet imaging system, our experiences with implementation, and outline the financial investment, space requirements, information technology needs, validation, and training of cytotechnologists needed to integrate such a system into a cytology laboratory. Before purchasing the imaging system, we evaluated and validated the instrument at our facility. Implementation required slide preparation changes, IT modifications, development of training programs, and revision of job descriptions for cytotechnologists. A darkened room was built to house the automated scanning station and microscope, as well as two imaging stations. IT changes included generation of storage for archival images on the LAN, addition of external hard drives for back-up, and changes to cable connections for communication between remote locations. Training programs for cytotechnologists, and pathologists/fellows/residents were developed, and cytotechnologists were integrated into multiple steps of the process. The imaging system has resulted in increased productivity for pathologists, concomitant with an expanded role of cytotechnologists in multiple critical steps, including FISH, scan setup, reclassification, and initial interpretation.

  20. PR-PR: cross-platform laboratory automation system.

    Science.gov (United States)

    Linshiz, Gregory; Stawski, Nina; Goyal, Garima; Bi, Changhao; Poust, Sean; Sharma, Monica; Mutalik, Vivek; Keasling, Jay D; Hillson, Nathan J

    2014-08-15

    To enable protocol standardization, sharing, and efficient implementation across laboratory automation platforms, we have further developed the PR-PR open-source high-level biology-friendly robot programming language as a cross-platform laboratory automation system. Beyond liquid-handling robotics, PR-PR now supports microfluidic and microscopy platforms, as well as protocol translation into human languages, such as English. While the same set of basic PR-PR commands and features are available for each supported platform, the underlying optimization and translation modules vary from platform to platform. Here, we describe these further developments to PR-PR, and demonstrate the experimental implementation and validation of PR-PR protocols for combinatorial modified Golden Gate DNA assembly across liquid-handling robotic, microfluidic, and manual platforms. To further test PR-PR cross-platform performance, we then implement and assess PR-PR protocols for Kunkel DNA mutagenesis and hierarchical Gibson DNA assembly for microfluidic and manual platforms.

  1. Control code for laboratory adaptive optics teaching system

    Science.gov (United States)

    Jin, Moonseob; Luder, Ryan; Sanchez, Lucas; Hart, Michael

    2017-09-01

    By sensing and compensating wavefront aberration, adaptive optics (AO) systems have proven themselves crucial in large astronomical telescopes, retinal imaging, and holographic coherent imaging. Commercial AO systems for laboratory use are now available in the market. One such is the ThorLabs AO kit built around a Boston Micromachines deformable mirror. However, there are limitations in applying these systems to research and pedagogical projects since the software is written with limited flexibility. In this paper, we describe a MATLAB-based software suite to interface with the ThorLabs AO kit by using the MATLAB Engine API and Visual Studio. The software is designed to offer complete access to the wavefront sensor data, through the various levels of processing, to the command signals to the deformable mirror and fast steering mirror. In this way, through a MATLAB GUI, an operator can experiment with every aspect of the AO system's functioning. This is particularly valuable for tests of new control algorithms as well as to support student engagement in an academic environment. We plan to make the code freely available to the community.

  2. Development of space simulation / net-laboratory system

    Science.gov (United States)

    Usui, H.; Matsumoto, H.; Ogino, T.; Fujimoto, M.; Omura, Y.; Okada, M.; Ueda, H. O.; Murata, T.; Kamide, Y.; Shinagawa, H.; Watanabe, S.; Machida, S.; Hada, T.

    A research project for the development of space simulation / net-laboratory system was approved by Japan Science and Technology Corporation (JST) in the category of Research and Development for Applying Advanced Computational Science and Technology(ACT-JST) in 2000. This research project, which continues for three years, is a collaboration with an astrophysical simulation group as well as other space simulation groups which use MHD and hybrid models. In this project, we develop a proto type of unique simulation system which enables us to perform simulation runs by providing or selecting plasma parameters through Web-based interface on the internet. We are also developing an on-line database system for space simulation from which we will be able to search and extract various information such as simulation method and program, manuals, and typical simulation results in graphic or ascii format. This unique system will help the simulation beginners to start simulation study without much difficulty or effort, and contribute to the promotion of simulation studies in the STP field. In this presentation, we will report the overview and the current status of the project.

  3. The Laboratory for Laser Energetics’ Hydrogen Isotope Separation System

    Energy Technology Data Exchange (ETDEWEB)

    Shmayda, W.T., E-mail: wshm@lle.rochester.edu; Wittman, M.D.; Earley, R.F.; Reid, J.L.; Redden, N.P.

    2016-11-01

    The University of Rochester’s Laboratory for Laser Energetics has commissioned a hydrogen Isotope Separation System (ISS). The ISS uses two columns—palladium on kieselguhr and molecular sieve—that act in a complementary manner to separate the hydrogen species by mass. The 4-sL per day throughput system is compact and has no moving parts. The columns and the attendant gas storage and handling subsystems are housed in a 0.8 -m{sup 3} glovebox. The glovebox uses a helium cover gas that is continuously processed to extract oxygen and water vapor that permeates through the glovebox gloves and any tritium that is released while attaching or detaching vessels to add feedstock to or drawing product from the system. The isotopic separation process is automated and does not require manual intervention. A total of 315 TBq of tritium was extracted from 23.6 sL of hydrogen with tritium purities reaching 99.5%. Deuterium was the sole residual component in the processed gas. Raffinate contained 0.2 TBq of activity was captured for reprocessing. The total emission from the system to the environment was 0.4 GBq over three weeks.

  4. Quality indicators from laboratory and radiology information systems.

    Science.gov (United States)

    Schuers, Matthieu; Joulakian, Mehr B; Griffon, Nicolas; Pachéco, Joanne; Périgard, Carine; Lepage, Eric; Watbled, Ludivine; Massari, Philippe; Darmoni, Stéfan J

    2015-01-01

    Consequences of the computerization of laboratory and radiology information system (LIS and RIS) are not well documented. The aim of this study was to evaluate the impact of computerization of LIS and RIS of four hospitals on performance and quality of care. The study was divided into three phases. First, the subprocesses and information flows of LIS and RIS were described. Then, a literature review was performed in order to identify the indicators used to assess the impact of computerization. Finally, comparisons were made between 2 hospitals. Using the initial framework, each partner described its process mapping concerning LIS and RIS. The review identified a wide panel of indicators. Only 41 were useful to assess the impact of information systems. For each two by two comparison, lists of relevant indicators have been selected from the identified indicators and according to the process mapping comparison. Two by two comparisons have to be completed. Eventually, these indicators may be integrated in the quality process of hospital information systems.

  5. Baobab Laboratory Information Management System: Development of an Open-Source Laboratory Information Management System for Biobanking.

    Science.gov (United States)

    Bendou, Hocine; Sizani, Lunga; Reid, Tim; Swanepoel, Carmen; Ademuyiwa, Toluwaleke; Merino-Martinez, Roxana; Meuller, Heimo; Abayomi, Akin; Christoffels, Alan

    2017-04-01

    A laboratory information management system (LIMS) is central to the informatics infrastructure that underlies biobanking activities. To date, a wide range of commercial and open-source LIMSs are available and the decision to opt for one LIMS over another is often influenced by the needs of the biobank clients and researchers, as well as available financial resources. The Baobab LIMS was developed by customizing the Bika LIMS software ( www.bikalims.org ) to meet the requirements of biobanking best practices. The need to implement biobank standard operation procedures as well as stimulate the use of standards for biobank data representation motivated the implementation of Baobab LIMS, an open-source LIMS for Biobanking. Baobab LIMS comprises modules for biospecimen kit assembly, shipping of biospecimen kits, storage management, analysis requests, reporting, and invoicing. The Baobab LIMS is based on the Plone web-content management framework. All the system requirements for Plone are applicable to Baobab LIMS, including the need for a server with at least 8 GB RAM and 120 GB hard disk space. Baobab LIMS is a server-client-based system, whereby the end user is able to access the system securely through the internet on a standard web browser, thereby eliminating the need for standalone installations on all machines.

  6. Environmental Molecular Sciences Laboratory Operations System: Version 4.0 - system requirements specification

    Energy Technology Data Exchange (ETDEWEB)

    Kashporenko, D.

    1996-07-01

    This document is intended to provide an operations standard for the Environmental Molecular Sciences Laboratory OPerations System (EMSL OPS). It is directed toward three primary audiences: (1) Environmental Molecular Sciences Laboratory (EMSL) facility and operations personnel; (2) laboratory line managers and staff; and (3) researchers, equipment operators, and laboratory users. It is also a statement of system requirements for software developers of EMSL OPS. The need for a finely tuned, superior research environment as provided by the US Department of Energy`s (DOE) Environmental Molecular Sciences Laboratory has never been greater. The abrupt end of the Cold War and the realignment of national priorities caused major US and competing overseas laboratories to reposition themselves in a highly competitive research marketplace. For a new laboratory such as the EMSL, this means coming into existence in a rapidly changing external environment. For any major laboratory, these changes create funding uncertainties and increasing global competition along with concomitant demands for higher standards of research product quality and innovation. While more laboratories are chasing fewer funding dollars, research ideas and proposals, especially for molecular-level research in the materials and biological sciences, are burgeoning. In such an economically constrained atmosphere, reduced costs, improved productivity, and strategic research project portfolio building become essential to establish and maintain any distinct competitive advantage. For EMSL, this environment and these demands require clear operational objectives, specific goals, and a well-crafted strategy. Specific goals will evolve and change with the evolution of the nature and definition of DOE`s environmental research needs. Hence, EMSL OPS is designed to facilitate migration of these changes with ease into every pertinent job function, creating a facile {open_quotes}learning organization.{close_quotes}

  7. Source Code Analysis Laboratory (SCALe) for Energy Delivery Systems

    Science.gov (United States)

    2010-12-01

    17025 :2005 General Requirements for the Competence of Testing and Cali- bration Laboratories, which specifies the requirements for sound management and...technical competence for the type of tests and calibrations SCALe undertakes. Testing and calibration laboratories that comply with ISO/IEC 17025 ... 17025 : 2005 General re- quirements for the competence of testing and calibration laboratories. CMU/SEI-2010-TR-021 | 32 3.5 Transition Transition

  8. Usability evaluation of Laboratory and Radiology Information Systems integrated into a hospital information system.

    Science.gov (United States)

    Nabovati, Ehsan; Vakili-Arki, Hasan; Eslami, Saeid; Khajouei, Reza

    2014-04-01

    This study was conducted to evaluate the usability of widely used laboratory and radiology information systems. Three usability experts independently evaluated the user interfaces of Laboratory and Radiology Information Systems using heuristic evaluation method. They applied Nielsen's heuristics to identify and classify usability problems and Nielsen's severity rating to judge their severity. Overall, 116 unique heuristic violations were identified as usability problems. In terms of severity, 67 % of problems were rated as major and catastrophic. Among 10 heuristics, "consistency and standards" was violated most frequently. Moreover, mean severity of problems concerning "error prevention" and "help and documentation" heuristics was higher than of the others. Despite widespread use of specific healthcare information systems, they suffer from usability problems. Improving the usability of systems by following existing design standards and principles from the early phased of system development life cycle is recommended. Especially, it is recommended that the designers design systems that inhibit the initiation of erroneous actions and provide sufficient guidance to users.

  9. Remote Laboratory and Animal Behaviour: An Interactive Open Field System

    Science.gov (United States)

    Fiore, Lorenzo; Ratti, Giovannino

    2007-01-01

    Remote laboratories can provide distant learners with practical acquisitions which would otherwise remain precluded. Our proposal here is a remote laboratory on a behavioural test (open field test), with the aim of introducing learners to the observation and analysis of stereotyped behaviour in animals. A real-time video of a mouse in an…

  10. [Assessment of the quality of laboratory diagnosis of intestinal parasitic diseases by the laboratories participating in the Federal System of External Quality Assessment of Clinical Laboratory Testing].

    Science.gov (United States)

    Malakhov, V N; Dovgalev, A S; Astanina, S Iu; Serdiuk, A P

    2014-01-01

    In 2010-2013, the quality of microscopic detection of the causative agents ofparasitic diseases in the feces has been assessed by the specialists of the laboratories of the therapeutic-and-prophylactic institutions (TPIs) and Hygiene and Epidemiology Centers, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare, which are participants of the Federal System of External Quality Assessment of Clinical Laboratory Testing. Thirty-two specimens containing 16 species of human helminths and 4 species of enteric protozoa in different combinations were examined. The findings suggest that the quality of microscopic detection of the causative agents of parasitic diseases is low in the laboratories of health care facilities and that the specialists of the laboratories of TPIs and Hygiene and Epidemiology Centers, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare, do not not possess the knowledge and skills necessary to make a laboratory diagnosis of helminths and enteric protozoa. The average detection rates of helminths and protozoa were at a level of 64 and 36%, respectively. The correct results showed that the proportion of helminths and protozoa were 94.5 and 5.5%, respectively. According to the biological and epidemiological classification of helminths, there were higher detection rates for contact group parasites (Enterobius vermicularis and Hymenolepis nana) and geohelminths (Ascaris, Trichuris trichiura, and others). Biohelminths (Opisthorchis, tapeworms, and others) Were detectable slightly worse.

  11. Virtual Earth System Laboratory (VESL): Effective Visualization of Earth System Data and Process Simulations

    Science.gov (United States)

    Quinn, J. D.; Larour, E. Y.; Cheng, D. L. C.; Halkides, D. J.

    2016-12-01

    The Virtual Earth System Laboratory (VESL) is a Web-based tool, under development at the Jet Propulsion Laboratory and UC Irvine, for the visualization of Earth System data and process simulations. It contains features geared toward a range of applications, spanning research and outreach. It offers an intuitive user interface, in which model inputs are changed using sliders and other interactive components. Current capabilities include simulation of polar ice sheet responses to climate forcing, based on NASA's Ice Sheet System Model (ISSM). We believe that the visualization of data is most effective when tailored to the target audience, and that many of the best practices for modern Web design/development can be applied directly to the visualization of data: use of negative space, color schemes, typography, accessibility standards, tooltips, etc cetera. We present our prototype website, and invite input from potential users, including researchers, educators, and students.

  12. Design of a Clinical Information Management System to Support DNA Analysis Laboratory Operation

    Science.gov (United States)

    Dubay, Christopher J.; Zimmerman, David; Popovich, Bradley

    1995-01-01

    The LabDirector system has been developed at the Oregon Health Sciences University to support the operation of our clinical DNA analysis laboratory. Through an iterative design process which has spanned two years, we have produced a system that is both highly tailored to a clinical genetics production laboratory and flexible in its implementation, to support the rapid growth and change of protocols and methodologies in use in the field. The administrative aspects of the system are integrated with an enterprise schedule management system. The laboratory side of the system is driven by a protocol modeling and execution system. The close integration between these two aspects of the clinical laboratory facilitates smooth operations, and allows management to accurately measure costs and performance. The entire application has been designed and documented to provide utility to a wide range of clinical laboratory environments.

  13. DSP-Based Hands-On Laboratory Experiments for Photovoltaic Power Systems

    Science.gov (United States)

    Muoka, Polycarp I.; Haque, Md. Enamul; Gargoom, Ameen; Negnetvitsky, Michael

    2015-01-01

    This paper presents a new photovoltaic (PV) power systems laboratory module that was developed to experimentally reinforce students' understanding of design principles, operation, and control of photovoltaic power conversion systems. The laboratory module is project-based and is designed to support a renewable energy course. By using MATLAB…

  14. Culturing Security System of Chemical Laboratory in Indonesia

    OpenAIRE

    Eka Dian Pusfitasari

    2017-01-01

    Indonesia has experiences on the lack of chemical security such as: a number of bombing terrors and hazardous chemicals found in food. Bomb used in terror is a homemade bomb made from chemicals which are widely spread in the research laboratories such as a mixture of pottasium chlorate, sulphur, and alumunium. Therefore, security of chemicals should be implemented to avoid the misused of the chemicals. Although it has experienced many cases of the misuse of chemicals, and many regulations and...

  15. Drain Back Systems in Laboratory and in Practice

    DEFF Research Database (Denmark)

    Perers, Bengt; Furbo, Simon; Fan, Jianhua

    2015-01-01

    with less components and that the performance can be enhanced. Also problems with long term degradation of glycol collector loops are totally avoided. A combination of the drain back and system expansion vessel was tested successfully. It is very important to achieve a continuous slope for the pipes...... step to have success with drain back systems. Practices used in glycol systems may give serious failures. Key-words: Drain Back, Low Flow, Solar Combi System, ETC collectors....

  16. Developing a customised approach for strengthening tuberculosis laboratory quality management systems toward accreditation

    Directory of Open Access Journals (Sweden)

    Heidi Albert

    2017-03-01

    Full Text Available Background: Quality-assured tuberculosis laboratory services are critical to achieve global and national goals for tuberculosis prevention and care. Implementation of a quality management system (QMS in laboratories leads to improved quality of diagnostic tests and better patient care. The Strengthening Laboratory Management Toward Accreditation (SLMTA programme has led to measurable improvements in the QMS of clinical laboratories. However, progress in tuberculosis laboratories has been slower, which may be attributed to the need for a structured tuberculosis-specific approach to implementing QMS. We describe the development and early implementation of the Strengthening Tuberculosis Laboratory Management Toward Accreditation (TB SLMTA programme.Development: The TB SLMTA curriculum was developed by customizing the SLMTA curriculum to include specific tools, job aids and supplementary materials specific to the tuberculosis laboratory. The TB SLMTA Harmonized Checklist was developed from the World Health Organisation Regional Office for Africa Stepwise Laboratory Quality Improvement Process Towards Accreditation checklist, and incorporated tuberculosis-specific requirements from the Global Laboratory Initiative Stepwise Process Towards Tuberculosis Laboratory Accreditation online tool.Implementation: Four regional training-of-trainers workshops have been conducted since 2013. The TB SLMTA programme has been rolled out in 37 tuberculosis laboratories in 10 countries using the Workshop approach in 32 laboratories in five countries and the Facility based approach in five tuberculosis laboratories in five countries.Conclusion: Lessons learnt from early implementation of TB SLMTA suggest that a structured training and mentoring programme can build a foundation towards further quality improvement in tuberculosis laboratories. Structured mentoring, and institutionalisation of QMS into country programmes, is needed to support tuberculosis laboratories to

  17. Developing a customised approach for strengthening tuberculosis laboratory quality management systems toward accreditation.

    Science.gov (United States)

    Albert, Heidi; Trollip, Andre; Erni, Donatelle; Kao, Kekeletso

    2017-01-01

    Quality-assured tuberculosis laboratory services are critical to achieve global and national goals for tuberculosis prevention and care. Implementation of a quality management system (QMS) in laboratories leads to improved quality of diagnostic tests and better patient care. The Strengthening Laboratory Management Toward Accreditation (SLMTA) programme has led to measurable improvements in the QMS of clinical laboratories. However, progress in tuberculosis laboratories has been slower, which may be attributed to the need for a structured tuberculosis-specific approach to implementing QMS. We describe the development and early implementation of the Strengthening Tuberculosis Laboratory Management Toward Accreditation (TB SLMTA) programme. The TB SLMTA curriculum was developed by customizing the SLMTA curriculum to include specific tools, job aids and supplementary materials specific to the tuberculosis laboratory. The TB SLMTA Harmonized Checklist was developed from the World Health Organisation Regional Office for Africa Stepwise Laboratory Quality Improvement Process Towards Accreditation checklist, and incorporated tuberculosis-specific requirements from the Global Laboratory Initiative Stepwise Process Towards Tuberculosis Laboratory Accreditation online tool. Four regional training-of-trainers workshops have been conducted since 2013. The TB SLMTA programme has been rolled out in 37 tuberculosis laboratories in 10 countries using the Workshop approach in 32 laboratories in five countries and the Facility-based approach in five tuberculosis laboratories in five countries. Lessons learnt from early implementation of TB SLMTA suggest that a structured training and mentoring programme can build a foundation towards further quality improvement in tuberculosis laboratories. Structured mentoring, and institutionalisation of QMS into country programmes, is needed to support tuberculosis laboratories to achieve accreditation.

  18. Developing a customised approach for strengthening tuberculosis laboratory quality management systems toward accreditation

    Directory of Open Access Journals (Sweden)

    Heidi Albert

    2017-03-01

    Full Text Available Background: Quality-assured tuberculosis laboratory services are critical to achieve global and national goals for tuberculosis prevention and care. Implementation of a quality management system (QMS in laboratories leads to improved quality of diagnostic tests and better patient care. The Strengthening Laboratory Management Toward Accreditation (SLMTA programme has led to measurable improvements in the QMS of clinical laboratories. However, progress in tuberculosis laboratories has been slower, which may be attributed to the need for a structured tuberculosis-specific approach to implementing QMS. We describe the development and early implementation of the Strengthening Tuberculosis Laboratory Management Toward Accreditation (TB SLMTA programme. Development: The TB SLMTA curriculum was developed by customizing the SLMTA curriculum to include specific tools, job aids and supplementary materials specific to the tuberculosis laboratory. The TB SLMTA Harmonized Checklist was developed from the World Health Organisation Regional Office for Africa Stepwise Laboratory Quality Improvement Process Towards Accreditation checklist, and incorporated tuberculosis-specific requirements from the Global Laboratory Initiative Stepwise Process Towards Tuberculosis Laboratory Accreditation online tool. Implementation: Four regional training-of-trainers workshops have been conducted since 2013. The TB SLMTA programme has been rolled out in 37 tuberculosis laboratories in 10 countries using the Workshop approach in 32 laboratories in five countries and the Facility based approach in five tuberculosis laboratories in five countries. Conclusion: Lessons learnt from early implementation of TB SLMTA suggest that a structured training and mentoring programme can build a foundation towards further quality improvement in tuberculosis laboratories. Structured mentoring, and institutionalisation of QMS into country programmes, is needed to support tuberculosis laboratories

  19. The impact of SLMTA in improving laboratory quality systems in the Caribbean Region

    Directory of Open Access Journals (Sweden)

    Giselle Guevara

    2014-11-01

    Objective: To describe the impact of the Strengthening of Laboratory Management Toward Accreditation (SLMTA training programme and mentorship amongst five clinical laboratories in the Caribbean after 18 months. Method: Five national reference laboratories from four countries participated in the SLMTA programme that incorporated classroom teaching and implementation of improvement projects. Mentors were assigned to the laboratories to guide trainees on their improvement projects and to assist in the development of Quality Management Systems (QMS. Audits were conducted at baseline, six months, exit (at 12 months and post-SLMTA (at 18 months using the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA checklist to measure changes in implementation of the QMS during the period. At the end of each audit, a comprehensive implementation plan was developed in order to address gaps. Results: Baseline audit scores ranged from 19% to 52%, corresponding to 0 stars on the SLIPTA five-star scale. After 18 months, one laboratory reached four stars, two reached three stars and two reached two stars. There was a corresponding decrease in nonconformities and development of over 100 management and technical standard operating procedures in each of the five laboratories. Conclusion: The tremendous improvement in these five Caribbean laboratories shows that SLMTA coupled with mentorship is an effective, user-friendly, flexible and customisable approach to the implementation of laboratory QMS. It is recommended that other laboratories in the region consider using the SLMTA training programme as they engage in quality systems improvement and preparation for accreditation.

  20. Development of a novel SCADA system for laboratory testing.

    Science.gov (United States)

    Patel, M; Cole, G R; Pryor, T L; Wilmot, N A

    2004-07-01

    This document summarizes the supervisory control and data acquisition (SCADA) system that allows communication with, and controlling the output of, various I/O devices in the renewable energy systems and components test facility RESLab. This SCADA system differs from traditional SCADA systems in that it supports a continuously changing operating environment depending on the test to be performed. The SCADA System is based on the concept of having one Master I/O Server and multiple client computer systems. This paper describes the main features and advantages of this dynamic SCADA system, the connections of various field devices to the master I/O server, the device servers, and numerous software features used in the system. The system is based on the graphical programming language "LabVIEW" and its "Datalogging and Supervisory Control" (DSC) module. The DSC module supports a real-time database called the "tag engine," which performs the I/O operations with all field devices attached to the master I/O server and communications with the other tag engines running on the client computers connected via a local area network. Generic and detailed communication block diagrams illustrating the hierarchical structure of this SCADA system are presented. The flow diagram outlining a complete test performed using this system in one of its standard configurations is described.

  1. Introduction to ISO 15189: a blueprint for quality systems in veterinary laboratories.

    Science.gov (United States)

    Freeman, Kathleen P; Bauer, Natali; Jensen, Asger L; Thoresen, Stein

    2006-06-01

    A trend in human and veterinary medical laboratory management is to achieve accreditation based on international standards. The International Organization for Standardization (ISO) 15189 standard is the first developed especially for accreditation of medical laboratories, and emphasizes the laboratory-client interface. European veterinary laboratories seeking to train candidates for the certification examination of the European College of Veterinary Clinical Pathology (ECVCP) require approval by the ECVCP Laboratory Standards Committee, which bases its evaluation in part on adherence to quality systems described in the ISO 15189 standards. The purpose of this article was to introduce the latest ISO quality standard and describe its application to veterinary laboratories in Europe, specifically as pertains to accreditation of laboratories involved in training veterinary clinical pathologists. Between 2003 and 2006, the Laboratory Standards Committee reviewed 12 applications from laboratories (3 commercial and 9 university) involved in training veterinary clinical pathologists. Applicants were asked to provide a description of the facilities for training and testing, current methodology and technology, health and safety policy, quality assurance policy (including internal quality control and participation in an external quality assurance program), written standard operating procedures (SOPs) and policies, a description of the laboratory information system, and personnel and training. Also during this time period multiple informal and formal discussions among ECVCP diplomates took place as to current practices and perceived areas of concern with regard to laboratory accreditation requirements. Areas in which improvement most often was needed in veterinary laboratories applying for ECVCP accreditation were the written quality plan, defined quality requirements for the tests performed, written SOPs and policies, training records, ongoing audits and competency

  2. Laboratory Scale Testing of Thermoelectric Regenerative Braking System

    National Research Council Canada - National Science Library

    P Sevvel; I S Stephan Thangaiah; S Mars Mukesh; G Mohammed Anif

    2015-01-01

      Thermoelectric Regenerative Braking System (TERBS) employs an energy recovery mechanism by utilizing the energy conversion at the time of braking in an automobile to generate electricity accordingly...

  3. Creating and Using a Computer Networking and Systems Administration Laboratory Built under Relaxed Financial Constraints

    Science.gov (United States)

    Conlon, Michael P.; Mullins, Paul

    2011-01-01

    The Computer Science Department at Slippery Rock University created a laboratory for its Computer Networks and System Administration and Security courses under relaxed financial constraints. This paper describes the department's experience designing and using this laboratory, including lessons learned and descriptions of some student projects…

  4. Mixed Methods Student Evaluation of an Online Systemic Human Anatomy Course with Laboratory

    Science.gov (United States)

    Attardi, Stefanie M.; Choi, Suwhan; Barnett, John; Rogers, Kem A.

    2016-01-01

    A fully online section of an existing face-to-face (F2F) systemic human anatomy course with a prosection laboratory was offered for the first time in 2012-2013. Lectures for F2F students (N = 365) were broadcast in both live and archived format to online students (N = 40) using virtual classroom software. Laboratories were delivered online by a…

  5. Hairy Root as a Model System for Undergraduate Laboratory Curriculum and Research

    Science.gov (United States)

    Keyes, Carol A.; Subramanian, Senthil; Yu, Oliver

    2009-01-01

    Hairy root transformation has been widely adapted in plant laboratories to rapidly generate transgenic roots for biochemical and molecular analysis. We present hairy root transformations as a versatile and adaptable model system for a wide variety of undergraduate laboratory courses and research. This technique is easy, efficient, and fast making…

  6. Planning an Automatic Fire Detection, Alarm, and Extinguishing System for Research Laboratories

    Directory of Open Access Journals (Sweden)

    Rostam Golmohamadi

    2014-04-01

    Full Text Available Background & Objectives: Educational and research laboratories in universities have a high risk of fire, because they have a variety of materials and equipment. The aim of this study was to provide a technical plan for safety improvement in educational and research laboratories of a university based on the design of automatic detection, alarm, and extinguishing systems . Methods : In this study, fire risk assessment was performed based on the standard of Military Risk Assessment method (MIL-STD-882. For all laboratories, detection and fire alarm systems and optimal fixed fire extinguishing systems were designed. Results : Maximum and minimum risks of fire were in chemical water and wastewater (81.2% and physical agents (62.5% laboratories, respectively. For studied laboratories, we designed fire detection systems based on heat and smoke detectors. Also in these places, fire-extinguishing systems based on CO2 were designed . Conclusion : Due to high risk of fire in studied laboratories, the best control method for fire prevention and protection based on special features of these laboratories is using automatic detection, warning and fire extinguishing systems using CO2 .

  7. Evolution and Integration of Medical Laboratory Information System in an Asia National Medical Center

    Science.gov (United States)

    Cheng, Po-Hsun; Chen, Sao-Jie; Lai, Jin-Shin

    This work elucidates the evolution of three generations of the laboratory information system in the National Taiwan University Hospital, which were respectively implemented in an IBM Series/1 mini-computer, a client/server and a plug-and-play HL7 interface engine environment respectively. The experience of using the HL7 healthcare information exchange in the hospital information system, laboratory information system, and automatic medical instruments over the past two decades are illustrated and discussed. The latest design challenge in developing intelligent laboratory information services is to organize effectively distributed and heterogeneous medical instruments through the message gateways. Such experiences had spread to some governmental information systems for different purposes in Taiwan; besides, the healthcare information exchange standard, software reuse mechanism, and application service provider adopted in developing the plug-and-play laboratory information system are also illustrated.

  8. Thermal performance of marketed SDHW systems under laboratory conditions

    DEFF Research Database (Denmark)

    Furbo, Simon; Andersen, Elsa; Fan, Jianhua

    A test facility for solar domestic hot water systems, SDHW systems was established at the Technical University of Denmark in 1992. During the period 1992-2012 21 marketed SDHW systems, 16 systems from Danish manufacturers and 5 systems from manufacturers from abroad, have been tested in the test ...... comfort, avoiding simple errors, using the low flow principle and heat stores with a high degree of thermal stratification and by using components with good thermal characteristics....... to the models were fitted in such a way, that the calculated thermal performance is in good agreement with the measured thermal performance, both for a typical winter period and for a typical summer period. In this way it is possible to use the simulation models to calculate the yearly thermal performance...

  9. On the study of ricochet and penetration in sand, water and gelatin by spheres, 7.62 mm APM2, and 25 mm projectiles

    Directory of Open Access Journals (Sweden)

    John F. Moxnes

    2016-04-01

    Full Text Available We examine the ricochet and penetration behavior in sand, water and gelatin by steel spheres, 7.62 mm APM2 and 25 mm projectiles. A threshold impact angle (critical angle exists beyond which ricochet cannot occur. The Autodyn simulation code with the smooth particle hydrodynamic (SPH method and Impetus Afea Solver with the corpuscular model are used and the results are compared with experimental and analytical results. The resistance force in sand for spheres was proportional to a term quadratic in velocity plus a term linear in velocity. The drag coefficient for the quadratic term was 0.65. The Autodyn and Impetus Afea codes simulate too large penetration due to the lack of a linear velocity resistance force. Critical ricochet angles were consistent with analytical results in the literature. In ballistic gelatin at velocities of 50–850 m/s a drag coefficient of 0.30 fits the high speed camera recordings if a linear velocity resistance term is included. However, only a quadratic velocity resistance force with drag coefficient that varies with the Reynolds number also fits the measurements. The simulation of a sphere in water with Autodyn showed too large drag coefficient. The 7.62 mm APM2 core simulations in sand fit reasonable well for both codes. The 25 mm projectile ricochet simulations in sand show consistency with the high speed camera recordings. Computer time was reduced by one to two orders of magnitudes when applying the Impetus Afea Solver compared to Autodyn code due to the use of the graphics processing units (GPU.

  10. The impact of SLMTA in improving laboratory quality systems in the Caribbean Region

    Directory of Open Access Journals (Sweden)

    Giselle Guevara

    2014-09-01

    Full Text Available Background: Past efforts to improve laboratory quality systems and to achieve accreditation for better patient care in the Caribbean Region have been slow.Objective: To describe the impact of the Strengthening of Laboratory Management Toward Accreditation (SLMTA training programme and mentorship amongst five clinical laboratories in the Caribbean after 18 months.Method: Five national reference laboratories from four countries participated in the SLMTA programme that incorporated classroom teaching and implementation of improvement projects. Mentors were assigned to the laboratories to guide trainees on their improvement projects and to assist in the development of Quality Management Systems (QMS. Audits were conducted at baseline, six months, exit (at 12 months and post-SLMTA (at 18 months using the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA checklist to measure changes in implementation of the QMS during the period. At the end of each audit, a comprehensive implementation plan was developed in order to address gaps.Results: Baseline audit scores ranged from 19% to 52%, corresponding to 0 stars on the SLIPTA five-star scale. After 18 months, one laboratory reached four stars, two reached three stars and two reached two stars. There was a corresponding decrease in nonconformities and development of over 100 management and technical standard operating procedures in each of the five laboratories.Conclusion: The tremendous improvement in these five Caribbean laboratories shows that SLMTA coupled with mentorship is an effective, user-friendly, flexible and customisable approach to the implementation of laboratory QMS. It is recommended that other laboratories in the region consider using the SLMTA training programme as they engage in quality systems improvement and preparation for accreditation.

  11. Laboratory information management system: an example of international cooperation in Namibia

    Directory of Open Access Journals (Sweden)

    Patrizia Colangeli

    2012-09-01

    Full Text Available The authors describe the project undertaken by the Istituto G. Caporale to provide a laboratory information management system (LIMS to the Central Veterinary Laboratory (CVL in Windhoek, Namibia. This robust laboratory management tool satisfies Namibia’s information obligations under international quality standard ISO 17025:2005. The Laboratory Information Management System (LIMS for Africa was designed to collect and manage all necessary information on samples, tests and test results. The system involves the entry of sample data on arrival, as required by Namibian sampling plans, the tracking of samples through the various sections of the CVL, the collection of test results, generation of test reports and monitoring of outbreaks through data interrogation functions, eliminating multiple registrations of the same data on paper records. It is a fundamental component of the Namibian veterinary information system.

  12. Laboratory information management system: an example of international cooperation in Namibia.

    Science.gov (United States)

    Colangeli, Patrizia; Ferrilli, Monica; Quaranta, Fabrizio; Malizia, Elio; Mbulu, Rosa-Stella; Mukete, Esther; Iipumbu, Lukas; Kamhulu, Anna; Tjipura-Zaire, Georgina; Di Francesco, Cesare; Lelli, Rossella; Scacchia, Massimo

    2012-01-01

    The authors describe the project undertaken by the Istituto G. Caporale to provide a laboratory information management system (LIMS) to the Central Veterinary Laboratory (CVL) in Windhoek, Namibia. This robust laboratory management tool satisfies Namibia's information obligations under international quality standard ISO 17025:2005. The Laboratory Information Management System (LIMS) for Africa was designed to collect and manage all necessary information on samples, tests and test results. The system involves the entry of sample data on arrival, as required by Namibian sampling plans, the tracking of samples through the various sections of the CVL, the collection of test results, generation of test reports and monitoring of outbreaks through data interrogation functions, eliminating multiple registrations of the same data on paper records. It is a fundamental component of the Namibian veterinary information system.

  13. The Laboratory of General Education and Evaluation System of the Catholic University SSIS

    Directory of Open Access Journals (Sweden)

    Paolo Ardizzone

    2003-01-01

    Full Text Available Description of the experience of e-learning in the School of Specialization for Secondary Teaching (SSIS University 'Cattolica, with particular reference to the Laboratory of General Education and Assessment System.

  14. A laboratory facility for electric vehicle propulsion system testing

    Science.gov (United States)

    Sargent, N. B.

    1980-01-01

    The road load simulator facility located at the NASA Lewis Research Center enables a propulsion system or any of its components to be evaluated under a realistic vehicle inertia and road loads. The load is applied to the system under test according to the road load equation: F(net)=K1F1+K2F2V+K3 sq V+K4(dv/dt)+K5 sin theta. The coefficient of each term in the equation can be varied over a wide range with vehicle inertial representative of vehicles up to 7500 pounds simulated by means of flywheels. The required torque is applied by the flywheels, a hydroviscous absorber and clutch, and a drive motor integrated by a closed loop control system to produce a smooth, continuous load up to 150 horsepower.

  15. Sandia National Laboratories, California sewer system management plan.

    Energy Technology Data Exchange (ETDEWEB)

    Holland, Robert C.

    2010-02-01

    A Sewer System Management Plan (SSMP) is required by the State Water Resources Control Board (SWRCB) Order No. 2006-0003-DWQ Statewide General Waste Discharge Requirements (WDR) for Sanitary Sewer Systems (General Permit). DOE, National Nuclear Security Administration (NNSA), Sandia Site Office has filed a Notice of Intent to be covered under this General Permit. The General Permit requires a proactive approach to reduce the number and frequency of sanitary sewer overflows (SSOs) within the State. SSMPs must include provisions to provide proper and efficient management, operation, and maintenance of sanitary sewer systems and must contain a spill response plan. Elements of this Plan are under development in accordance with the SWRCB's schedule.

  16. HVAC systems in a field laboratory for indoor climate study

    DEFF Research Database (Denmark)

    Fang, Lei; Melikov, Arsen Krikor; Olesen, Bjarne W.

    2012-01-01

    convectors. The field lab was designed for experimental research, education and demonstration of ventilation and air-conditioning principals with special focus on studying the impact of different air distribution and heating/cooling methods on human comfort and health. The system can also be used for testing...... under realistic conditions the performance of air processing units (e.g. a special air handling unit, an air cleaning devices, etc.) including their energy consumption and human response. The field lab can accommodate up to 50 occupants and supply 750 L/s of conditioned outdoor fresh air...... with the controlled room temperature in the range from 10 to 35 °C and relative humidity in the range from 15 to 80 %. The field lab can be used to test the performance of each system included in the field lab as well as the combined performance of two or more systems....

  17. Quality management systems for your in vitro fertilization clinic's laboratory: Why bother?

    OpenAIRE

    Olofsson, Jan I; Banker, Manish R; Late Peter Sjoblom

    2013-01-01

    Several countries have in recent years introduced prescribed requirements for treatment and monitoring of outcomes, as well as a licensing or accreditation requirement for in vitro fertilization (IVF) clinics and their laboratories. It is commonplace for Assisted Reproductive Technology (ART) laboratories to be required to have a quality control system. However, more effective Total Quality Management systems are now being implemented by an increasing number of ART clinics. In India, it is no...

  18. Flexible System Integration and Advanced Hierarchical Control Architectures in the Microgrid Research Laboratory of Aalborg University

    DEFF Research Database (Denmark)

    Meng, Lexuan; Hernández, Adriana Carolina Luna; Diaz, Enrique Rodriguez

    2016-01-01

    This paper presents the system integration and hierarchical control implementation in an inverter-based microgrid research laboratory (MGRL) in Aalborg University, Denmark. MGRL aims to provide a flexible experimental platform for comprehensive studies of microgrids. The structure of the laboratory...... system supervision, advanced secondary and tertiary management are realized in a microgrid central controller. The software and hardware schemes are described. Several example case studies are introduced and performed in order to achieve power quality regulation, energy management and flywheel energy...

  19. Laboratory systems and services are critical in global health: time to end the neglect?

    Science.gov (United States)

    Nkengasong, John N; Nsubuga, Peter; Nwanyanwu, Okey; Gershy-Damet, Guy-Michel; Roscigno, Giorgio; Bulterys, Marc; Schoub, Barry; DeCock, Kevin M; Birx, Deborah

    2010-09-01

    The $63 billion comprehensive global health initiative (GHI) emphasizes health systems strengthening (HSS) to tackle challenges, including child and maternal health, HIV/AIDS, family planning, and neglected tropical diseases. GHI and other initiatives are critical to fighting emerging and reemerging diseases in resource-poor countries. HSS is also an increasing focus of the $49 billion program of the US President's Emergency Plan for AIDS Relief and the Global Fund to Fight AIDS, Tuberculosis and Malaria. Laboratory systems and services are often neglected in resource-poor settings, but the funding offers an opportunity to end the neglect. To sustainably strengthen national laboratory systems in resource-poor countries, the following approaches are needed: (1) developing integrative national laboratory strategic plans and policies and building systems to address multiple diseases; (2) establishing public-private partnerships; (3) ensuring effective leadership, commitment, and coordination by host governments of efforts of donors and partners; (4) establishing and/or strengthening centers of excellence and field epidemiology and laboratory training programs to meet short- and medium-term training and retention goals; and (5) establishing affordable, scalable, and effective laboratory accreditation schemes to ensure quality of laboratory tests and bridge the gap between clinicians and laboratory experts on the use of test results.

  20. US Department of Energy Laboratory Accredition Program (DOELAP) for personnel dosimetry systems

    Energy Technology Data Exchange (ETDEWEB)

    Cummings, F.M.; Carlson, R.D.; Loesch, R.M.

    1993-12-31

    Accreditation of personnel dosimetry systems is required for laboratories that conduct personnel dosimetry for the U.S. Department of Energy (DOE). Accreditation is a two-step process which requires the participant to pass a proficiency test and an onsite assessment. The DOE Laboratory Accreditation Program (DOELAP) is a measurement quality assurance program for DOE laboratories. Currently, the DOELAP addresses only dosimetry systems used to assess the whole body dose to personnel. A pilot extremity DOELAP has been completed and routine testing is expected to begin in January 1994. It is expected that participation in the extremity program will be a regulatory requirement by January 1996.

  1. Proceedings of the National Renewable Energy Laboratory Wind Energy Systems Engineering Workshop

    Energy Technology Data Exchange (ETDEWEB)

    Dykes, K.

    2014-12-01

    The second National Renewable Energy Laboratory (NREL) Wind Energy Systems Engineering Workshop was held in Broomfield, Colorado, from January 29 to February 1, 2013. The event included a day-and-a-half workshop exploring a wide variety of topics related to system modeling and design of wind turbines and plants. Following the workshop, 2 days of tutorials were held at NREL, showcasing software developed at Sandia National Laboratories, the National Aeronautics and Space Administration's Glenn Laboratories, and NREL. This document provides a brief summary of the various workshop activities and includes a review of the content and evaluation results from attendees.

  2. Air Force Geophysics Laboratory Management Information System Study.

    Science.gov (United States)

    1985-11-01

    management information system (MIS) at AFGL. The study summarizes current management and administrative practices at AFGL. Requirements have been identified for automating several currently manual functions to compile accurate and timely information to better manage and plan AFGL programs. This document describes the functions and relative priorities of five MIS subsystems and provides suggestions for implementation solutions. Creation of a detailed Development Plan is recommended as the follow-on task.

  3. Equipment Proposal for the Autonomous Vehicle Systems Laboratory at UIW

    Science.gov (United States)

    2015-04-29

    testing, 5) 38 Lego Mindstorm EV3 and Hitechnic Sensors for use in feedback control and autonomous systems for STEM undergraduate and High School...autonomous robots using the Lego Mindstorm EV3 . This robotics workshop will be used as a pilot study for next summer when more High School students...Program for Fall 2014 and Spring 2015 Semesters. The student researched path planning using the EV3 robots. During the Fall 2014 Semester, the AVS

  4. Industrial Scale Energy Systems Integration; NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    Ruth, Mark

    2015-07-28

    The industrial sector consumes 25% of the total energy in the U.S. and produces 18% of the greenhouse gas (GHG) emissions. Energy Systems Integration (ESI) opportunities can reduce those values and increase the profitability of that sector. This presentation outlines several options. Combined heat and power (CHP) is an option that is available today for many applications. In some cases, it can be extended to trigeneration by adding absorbtion cooling. Demand response is another option in use by the industrial sector - in 2012, industry provided 47% of demand response capacity. A longer term option that combines the benefits of CHP with those of demand response is hybrid energy systems (HESs). Two possible HESs are described and development implications discussed. extended to trigeneration by adding absorbtion cooling. Demand response is another option in use by the industrial sector - in 2012, industry provided 47% of demand response capacity. A longer term option that combines the benefits of CHP with those of demand response is hybrid energy systems (HESs). Two possible HESs are described and development implications discussed.

  5. The double pulsar system: a unique laboratory for gravity

    Energy Technology Data Exchange (ETDEWEB)

    Kramer, M; Wex, N, E-mail: michael.kramer@manchester.ac.u [Max-Planck-Institut fuer Radioastronomie, Auf dem Huegel 69, D-53121 Bonn (Germany)

    2009-04-07

    The PSR J0737-3039 is a double neutron star system in which both stars are detectable as active radio pulsars. The pair, consisting of an old, mildly recycled 23-ms pulsar and a young 2.8-s pulsar, orbit the common centre of mass in a slightly eccentric, compact orbit with a short orbital period of 147 min. The combination of system parameters makes this binary pulsar the most relativistic binary pulsar known and allows unique tests of general relativity and alternative theories of gravity. Hence, we summarize the importance of the system for such tests, and pay attention, for instance, to the observed measurement of relativistic spin precession which confirms the 'effacement' property of a spinning body. We also present a method to use measurements of the absolute position angle of the linearly polarized radio emission of the pulsars to measure the rate of the relativistic spin precession. We demonstrate how spin-orbit coupling will eventually allow us to determine the moment-of-inertia of pulsar A, and provide a general outlook into the prospects of future observations of the double pulsar. (topical review)

  6. Role of a quality management system in improving patient safety - laboratory aspects.

    Science.gov (United States)

    Allen, Lynn C

    2013-09-01

    The aim of this study is to describe how implementation of a quality management system (QMS) based on ISO 15189 enhances patient safety. A literature review showed that several European hospitals implemented a QMS based on ISO 9001 and assessed the impact on patient safety. An Internet search showed that problems affecting patient safety have occurred in a number of laboratories across Canada. The requirements of a QMS based on ISO 15189 are outlined, and the impact of the implementation of each requirement on patient safety is summarized. The Quality Management Program - Laboratory Services in Ontario is briefly described, and the experience of Ontario laboratories with Ontario Laboratory Accreditation, based on ISO 15189, is outlined. Several hospitals that implemented ISO 9001 reported either a positive impact or no impact on patient safety. Patient safety problems in Canadian laboratories are described. Implementation of each requirement of the QMS can be seen to have a positive effect on patient safety. Average laboratory conformance on Ontario Laboratory Accreditation is very high, and laboratories must address and resolve any nonconformities. Other standards, practices, and quality requirements may also contribute to patient safety. Implementation of a QMS based on ISO 15189 provides a solid foundation for quality in the laboratory and enhances patient safety. It helps to prevent patient safety issues; when such issues do occur, effective processes are in place for investigation and resolution. Patient safety problems in Canadian laboratories might have been prevented had effective QMSs been in place. Ontario Laboratory Accreditation has had a positive impact on quality in Ontario laboratories. Copyright © 2013 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  7. Comparison of the fate and toxicity of chlorpyrifos--laboratory versus a coastal mesocosm system.

    Science.gov (United States)

    Pablo, F; Krassoi, F R; Jones, P R F; Colville, A E; Hose, G C; Lim, R P

    2008-09-01

    The widespread use of chlorpyrifos for pest control in urban and rural environments poses a risk of contamination to aquatic environments via runoff, spray drift or spillage. The aim of this study was to assess the fate of chlorpyrifos and its toxicity to common freshwater invertebrates in the laboratory and in stream mesocosms. Chlorpyrifos was rapidly lost from the test systems but the rates of loss varied considerably, such that losses in the mesocosms could not be reliably predicted from the static laboratory studies. This was likely due to the mass transport of chlorpyrifos from the mesocosm via stream flow. Chlorpyrifos was acutely toxic to all invertebrates tested with the cladoceran species (laboratory 48h LC(50) values 0.07-0.10 microg L(-1)) being most sensitive. Despite the differences in the dynamics of chlorpyrifos in the laboratory and mesocosm systems, the sensitivities of the mayfly Atalophlebia australis and the cladoceran Simocephalus vetulus were similar in the 2 systems.

  8. The laboratory health system and its response to the Ebola virus disease outbreak in Liberia

    Directory of Open Access Journals (Sweden)

    Stephen B. Kennedy

    2016-10-01

    Full Text Available The laboratory system in Liberia has generally been fragmented and uncoordinatedAccordingly, the country’s Ministry of Health established the National Reference Laboratoryto strengthen and sustain laboratory services. However, diagnostic testing services were oftenlimited to clinical tests performed in health facilities, with the functionality of the NationaReference Laboratory restricted to performing testing services for a limited number ofepidemic-prone diseases. The lack of testing capacity in-country for Lassa fever and otherhaemorrhagic fevers affected the response of the country’s health system during the onset ofthe Ebola virus disease (EVD outbreak. Based on the experiences of the EVD outbreak, effortswere initiated to strengthen the laboratory system and infrastructure, enhance human resourcecapacity, and invest in diagnostic services and public health surveillance to inform admittancetreatment, and discharge decisions. In this article, we briefly describe the pre-EVD laboratorycapability in Liberia, and extensively explore the post-EVD strengthening initiatives to enhancecapacity, mobilise resources and coordinate disaster response with international partners torebuild the laboratory infrastructure in the country. Now that the EVD outbreak has endedadditional initiatives are needed to revise the laboratory strategic and operational plan forpost-EVD relevance, promote continual human resource capacity, institute accreditation andvalidation programmes, and coordinate the investment strategy to strengthen and sustain thepreparedness of the laboratory sector to mitigate future emerging and re-emerging infectiousdiseases.

  9. Laboratory evaluation of the pointing stability of the ASPS Vernier System

    Science.gov (United States)

    1980-01-01

    The annular suspension and pointing system (ASPS) is an end-mount experiment pointing system designed for use in the space shuttle. The results of the ASPS Vernier System (AVS) pointing stability tests conducted in a laboratory environment are documented. A simulated zero-G suspension was used to support the test payload in the laboratory. The AVS and the suspension were modelled and incorporated into a simulation of the laboratory test. Error sources were identified and pointing stability sensitivities were determined via simulation. Statistical predictions of laboratory test performance were derived and compared to actual laboratory test results. The predicted mean pointing stability during simulated shuttle disturbances was 1.22 arc seconds; the actual mean laboratory test pointing stability was 1.36 arc seconds. The successful prediction of laboratory test results provides increased confidence in the analytical understanding of the AVS magnetic bearing technology and allows confident prediction of in-flight performance. Computer simulations of ASPS, operating in the shuttle disturbance environment, predict in-flight pointing stability errors less than 0.01 arc seconds.

  10. MASTR-MS: a web-based collaborative laboratory information management system (LIMS) for metabolomics.

    Science.gov (United States)

    Hunter, Adam; Dayalan, Saravanan; De Souza, David; Power, Brad; Lorrimar, Rodney; Szabo, Tamas; Nguyen, Thu; O'Callaghan, Sean; Hack, Jeremy; Pyke, James; Nahid, Amsha; Barrero, Roberto; Roessner, Ute; Likic, Vladimir; Tull, Dedreia; Bacic, Antony; McConville, Malcolm; Bellgard, Matthew

    2017-01-01

    An increasing number of research laboratories and core analytical facilities around the world are developing high throughput metabolomic analytical and data processing pipelines that are capable of handling hundreds to thousands of individual samples per year, often over multiple projects, collaborations and sample types. At present, there are no Laboratory Information Management Systems (LIMS) that are specifically tailored for metabolomics laboratories that are capable of tracking samples and associated metadata from the beginning to the end of an experiment, including data processing and archiving, and which are also suitable for use in large institutional core facilities or multi-laboratory consortia as well as single laboratory environments. Here we present MASTR-MS, a downloadable and installable LIMS solution that can be deployed either within a single laboratory or used to link workflows across a multisite network. It comprises a Node Management System that can be used to link and manage projects across one or multiple collaborating laboratories; a User Management System which defines different user groups and privileges of users; a Quote Management System where client quotes are managed; a Project Management System in which metadata is stored and all aspects of project management, including experimental setup, sample tracking and instrument analysis, are defined, and a Data Management System that allows the automatic capture and storage of raw and processed data from the analytical instruments to the LIMS. MASTR-MS is a comprehensive LIMS solution specifically designed for metabolomics. It captures the entire lifecycle of a sample starting from project and experiment design to sample analysis, data capture and storage. It acts as an electronic notebook, facilitating project management within a single laboratory or a multi-node collaborative environment. This software is being developed in close consultation with members of the metabolomics research

  11. The water cycle in closed ecological systems: perspectives from the Biosphere 2 and Laboratory Biosphere systems

    Science.gov (United States)

    Nelson, Mark; Dempster, William; Allen, John P.

    To achieve sustainable and healthy closed ecological systems requires successful solutions to the challenge of closing the water cycle - recycling wastewater/soil leachate and evaporateed water and supplying water of required quality as needed for different needs within the facility. Engineering Biosphere 2, the first multi-biome closed ecological system, total footprint of the airtight area is 12,700 m2 with a combined volume of 200,000 m3 with a total water capacity of some 6 x 106 liters of water presented a complex challenge because it included human inhabitants, their agricultural and technical systems, as well as a range of analogue ecosystems ranging from rainforest to desert, freshwater ecologies to mini-ocean coral reef ecosystems. By contrast, the Laboratory Biosphere - a small (40m3 volume) soil-based plant growth facility with a footprint of 15m3 - is a very simplified system, but with some similar issues such as salinity management and the provision of water quality sufficient for plant growth. In Biosphere 2, water needs included supplying potable water for people and domestic animals, irrigation water for a wide variety of food crops, and recycling and recovering soil nutrients from wastewater. In the wilderness biomes, adequately freshwater was needed for terrestrial ecosystems and maintaining appropriate salinity and pH in aquatic/marine ecosystems. The largest reservoirs in Biosphere 2 were the ocean/marsh with some 4x106 liters, soil with 2 x 106 liters, primary storage tanks with a capacity for up to 8 x 105 liters and storage tanks for condensate collection and mixing tanks with 1.5 x 105 liters to supply irrigation for farm and wilderness ecosystems. Other reservoirs were far smaller - humidity in the atmosphere (2 x 103 liters), streams in the rainforest and savannah, and seasonal pools in the desert were orders of magnitude smaller (8 x 103 liters). Key technologies included condensation from humidity in the airhandlers and from the glass

  12. Note: Measurement system for the radiative forcing of greenhouse gases in a laboratory scale.

    Science.gov (United States)

    Kawamura, Yoshiyuki

    2016-01-01

    The radiative forcing of the greenhouse gases has been studied being based on computational simulations or the observation of the real atmosphere meteorologically. In order to know the greenhouse effect more deeply and to study it from various viewpoints, the study on it in a laboratory scale is important. We have developed a direct measurement system for the infrared back radiation from the carbon dioxide (CO2) gas. The system configuration is similar with that of the practical earth-atmosphere-space system. Using this system, the back radiation from the CO2 gas was directly measured in a laboratory scale, which roughly coincides with meteorologically predicted value.

  13. The LabBase system for data management in large scale biology research laboratories.

    Science.gov (United States)

    Goodman, N; Rozen, S; Stein, L D; Smith, A G

    1998-01-01

    The development of laboratory information management systems (LIMSs) for large scale biology research projects can be a challenging problem. Many such projects generate complex datasets via complex procedures that undergo continuous refinement. A key software challenge is to simplify the database-development task so that databases can be built and modified quickly enough to keep pace with changing project-requirements. LabBase extends the facilities offered by relational database systems to simplify the task of creating databases for large scale biology research projects. LabBase provides a structural object data model, similar to ACEDB, and adds to this the concepts of Materials, Steps, and States: Materials are objects representing the identifiable things that participate in a laboratory protocol; Steps are objects reporting the results of a laboratory or analytical procedure; and States are objects denoting places in a laboratory protocol. The system provides a data definition language for succinctly defining laboratory databases, and operations for conveniently storing and retrieving data in such databases. The system also provides support for workflow management. LabBase is implemented in Perl5 and provides a natural interface for laboratory application programs written in Perl. The software is freely available. Contact the authors. nat@jax.org

  14. Implementation of a configurable laboratory information management system for use in cellular process development and manufacturing.

    Science.gov (United States)

    Russom, Diana; Ahmed, Amira; Gonzalez, Nancy; Alvarnas, Joseph; DiGiusto, David

    2012-01-01

    Regulatory requirements for the manufacturing of cell products for clinical investigation require a significant level of record-keeping, starting early in process development and continuing through to the execution and requisite follow-up of patients on clinical trials. Central to record-keeping is the management of documentation related to patients, raw materials, processes, assays and facilities. To support these requirements, we evaluated several laboratory information management systems (LIMS), including their cost, flexibility, regulatory compliance, ongoing programming requirements and ability to integrate with laboratory equipment. After selecting a system, we performed a pilot study to develop a user-configurable LIMS for our laboratory in support of our pre-clinical and clinical cell-production activities. We report here on the design and utilization of this system to manage accrual with a healthy blood-donor protocol, as well as manufacturing operations for the production of a master cell bank and several patient-specific stem cell products. The system was used successfully to manage blood donor eligibility, recruiting, appointments, billing and serology, and to provide annual accrual reports. Quality management reporting features of the system were used to capture, report and investigate process and equipment deviations that occurred during the production of a master cell bank and patient products. Overall the system has served to support the compliance requirements of process development and phase I/II clinical trial activities for our laboratory and can be easily modified to meet the needs of similar laboratories.

  15. Systems integration for the Kennedy Space Center (KSC) Robotics Applications Development Laboratory (RADL)

    Science.gov (United States)

    Davis, V. Leon; Nordeen, Ross

    1988-01-01

    A laboratory for developing robotics technology for hazardous and repetitive Shuttle and payload processing activities is discussed. An overview of the computer hardware and software responsible for integrating the laboratory systems is given. The center's anthropomorphic robot is placed on a track allowing it to be moved to different stations. Various aspects of the laboratory equipment are described, including industrial robot arm control, smart systems integration, the supervisory computer, programmable process controller, real-time tracking controller, image processing hardware, and control display graphics. Topics of research include: automated loading and unloading of hypergolics for space vehicles and payloads; the use of mobile robotics for security, fire fighting, and hazardous spill operations; nondestructive testing for SRB joint and seal verification; Shuttle Orbiter radiator damage inspection; and Orbiter contour measurements. The possibility of expanding the laboratory in the future is examined.

  16. Laboratory Experimental System for Examination of Acoustic Emission Generated by Partial Discharges

    Directory of Open Access Journals (Sweden)

    I. M. Salom

    2013-11-01

    Full Text Available One of the major causes of transformer failures is dielectric breakdown. Partial discharges cause gradual insulation degradation thus partial discharge activity monitoring provides transformer state insight. This paper gives an overview of common methods for partial discharges detection and source location in transformers, with a special reference to the acoustic method as an noninvasive and interference resistant method suitable for application. For laboratory testing a laboratory experimental system for partial discharge diagnostics using acoustic emission measurement was developed.

  17. Electronic laboratory system reduces errors in National Tuberculosis Program: a cluster randomized controlled trial.

    Science.gov (United States)

    Blaya, J A; Shin, S S; Yale, G; Suarez, C; Asencios, L; Contreras, C; Rodriguez, P; Kim, J; Cegielski, P; Fraser, H S F

    2010-08-01

    To evaluate the impact of the e-Chasqui laboratory information system in reducing reporting errors compared to the current paper system. Cluster randomized controlled trial in 76 health centers (HCs) between 2004 and 2008. Baseline data were collected every 4 months for 12 months. HCs were then randomly assigned to intervention (e-Chasqui) or control (paper). Further data were collected for the same months the following year. Comparisons were made between intervention and control HCs, and before and after the intervention. Intervention HCs had respectively 82% and 87% fewer errors in reporting results for drug susceptibility tests (2.1% vs. 11.9%, P = 0.001, OR 0.17, 95%CI 0.09-0.31) and cultures (2.0% vs. 15.1%, P Chasqui users sent on average three electronic error reports per week to the laboratories. e-Chasqui reduced the number of missing laboratory results at point-of-care health centers. Clinical users confirmed viewing electronic results not available on paper. Reporting errors to the laboratory using e-Chasqui promoted continuous quality improvement. The e-Chasqui laboratory information system is an important part of laboratory infrastructure improvements to support multidrug-resistant tuberculosis care in Peru.

  18. Statement of Work Electrical Energy Storage System Installation at Sandia National Laboratories.

    Energy Technology Data Exchange (ETDEWEB)

    Schenkman, Benjamin L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-03-01

    Sandia is seeking to procure a 1 MWh energy storage system. It will be installed at the existing Energy Storage Test Pad, which is located at Sandia National Laboratories in Albuquerque, New Mexico. This energy storage system will be a daily operational system, but will also be used as a tool in our Research and development work. The system will be part of a showcase of Sandia distributed energy technologies viewed by many distinguished delegates.

  19. The water cycle in closed ecological systems: Perspectives from the Biosphere 2 and Laboratory Biosphere systems

    Science.gov (United States)

    Nelson, Mark; Dempster, W. F.; Allen, J. P.

    2009-12-01

    To achieve sustainable, healthy closed ecological systems requires solutions to challenges of closing the water cycle - recycling wastewater/irrigation water/soil medium leachate and evaporated water and supplying water of required quality as needed for different needs within the facility. Engineering Biosphere 2, the first multi-biome closed ecological system within a total airtight footprint of 12,700 m 2 with a combined volume of 200,000 m 3 with a total water capacity of some 6 × 10 6 L of water was especially challenging because it included human inhabitants, their agricultural and technical systems, as well as five analogue ecosystems ranging from rainforest to desert, freshwater ecologies to saltwater systems like mangrove and mini-ocean coral reef ecosystems. By contrast, the Laboratory Biosphere - a small (40 m 3 volume) soil-based plant growth facility with a footprint of 15 m 2 - is a very simplified system, but with similar challenges re salinity management and provision of water quality suitable for plant growth. In Biosphere 2, water needs included supplying potable water for people and domestic animals, irrigation water for a wide variety of food crops, and recycling and recovering soil nutrients from wastewater. In the wilderness biomes, providing adequately low salinity freshwater terrestrial ecosystems and maintaining appropriate salinity and pH in aquatic/marine ecosystems were challenges. The largest reservoirs in Biosphere 2 were the ocean/marsh with some 4 × 10 6 L, soil with 1 to 2 × 10 6 l, primary storage tank with 0 to 8 × 10 5 L and storage tanks for condensate and soil leachate collection and mixing tanks with a capacity of 1.6 × 10 5 L to supply irrigation for farm and wilderness ecosystems. Other reservoirs were far smaller - humidity in the atmosphere (2 × 10 3 L), streams in the rainforest and savannah, and seasonal pools in the desert were orders of magnitude smaller (8 × 10 4 L). Key technologies included condensation from

  20. Laboratory QA/QC improvements for small drinking water systems at Savannah River Site

    Energy Technology Data Exchange (ETDEWEB)

    Turner, R.D.

    1995-12-01

    The Savannah River Site (SRS), a 310 square mile facility located near Aiken, S.C., is operated by Westinghouse Savannah River Company for the US Department of Energy. SRS has 28 separate drinking water systems with average daily demands ranging from 0.0002 to 0.5 MGD. All systems utilize treated groundwater. Until recently, the water laboratories for each system operated independently. As a result, equipment, reagents, chemicals, procedures, personnel, and quality control practices differed from location to location. Due to this inconsistency, and a lack of extensive laboratory OA/QC practices at some locations, SRS auditors were not confident in the accuracy of daily water quality analyses results. The Site`s Water Services Department addressed these concerns by developing and implementing a practical laboratory QA/QC program. Basic changes were made which can be readily adopted by most small drinking water systems. Key features of the program include: Standardized and upgraded laboratory instrumentation and equipment; standardized analytical procedures based on vendor manuals and site requirements; periodic accuracy checks for all instrumentation; creation of a centralized laboratory to perform metals digestions and chlorine colorimeter accuracy checks; off-site and on-site operator training; proper storage, inventory and shelf life monitoring for reagents and chemicals. This program has enhanced the credibility and accuracy of SRS drinking water system analyses results.

  1. On the atmospheric chemistry of NO2 - O3 systems : a laboratory study

    NARCIS (Netherlands)

    Verhees, P.W.C.

    1986-01-01

    In this dissertation a laboratory study dealing with the atmospheric chemistry of NO 2 -O 3 systems is described. Knowledge of this system is relevant for a better

  2. Anatomy of a failure: A sociotechnical evaluation of a laboratory physician order entry system implementation

    NARCIS (Netherlands)

    Peute, Linda W.; Aarts, Jos; Bakker, Piet J. M.; Jaspers, Monique W. M.

    2010-01-01

    Objective: To investigate the human, social and organizational issues surrounding a Computerized Physician Order Entry system for Laboratory ordering (CPOE-L) implementation process and to analyze their interrelated effects on the system implementation failure in an academic medical setting. Second,

  3. Model-based fuzzy control solutions for a laboratory Antilock Braking System

    DEFF Research Database (Denmark)

    Precup, Radu-Emil; Spataru, Sergiu; Rǎdac, Mircea-Bogdan

    2010-01-01

    This paper gives two original model-based fuzzy control solutions dedicated to the longitudinal slip control of Antilock Braking System laboratory equipment. The parallel distributed compensation leads to linear matrix inequalities which guarantee the global stability of the fuzzy control systems...

  4. Assessment of laboratory logistics management information system practice for HIV/AIDS and tuberculosis laboratory commodities in selected public health facilities in Addis Ababa, Ethiopia.

    Science.gov (United States)

    Desale, Adino; Taye, Bineyam; Belay, Getachew; Nigatu, Alemayehu

    2013-01-01

    Logistics management information system for health commodities remained poorly implemented in most of developing countries. To assess the status of laboratory logistics management information system for HIV/AIDS and tuberculosis laboratory commodities in public health facilities in Addis Ababa. A cross-sectional descriptive study was conducted from September 2010-January 2011 at selected public health facilities. A stratified random sampling method was used to include a total of 43 facilities which, were investigated through quantitative methods using structured questionnaires interviews. Focus group discussion with the designated supply chain managers and key informant interviews were conducted for the qualitative method. There exists a well-designed logistics system for laboratory commodities with trained pharmacy personnel, distributed standard LMIS formats and established inventory control procedures. However, majority of laboratory professionals were not trained in LMIS. Majority of the facilities (60.5%) were stocked out for at least one ART monitoring and TB laboratory reagents and the highest stock out rate was for chemistry reagents. Expired ART monitoring laboratory commodities were found in 25 (73.5%) of facilities. Fifty percent (50%) of the assessed hospitals and 54% of health centers were currently using stock/bin cards for all HIV/AIDS and TB laboratory commodities in main pharmacy store, among these only 25% and 20.8% of them were updated with accurate information matching with the physical count done at the time of visit for hospitals and health centers respectively. Even though there exists a well designed laboratory LMIS, keeping quality stock/bin cards and LMIS reports were very low. Key ART monitoring laboratory commodities were stock out at many facilities at the day of visit and during the past six months. Based on findings, training of laboratory personnel's managing laboratory commodities and keeping accurate inventory control procedures

  5. Assessment of laboratory logistics management information system practice for HIV/AIDS and tuberculosis laboratory commodities in selected public health facilities in Addis Ababa, Ethiopia

    Science.gov (United States)

    Desale, Adino; Taye, Bineyam; Belay, Getachew; Nigatu, Alemayehu

    2013-01-01

    Introduction Logistics management information system for health commodities remained poorly implemented in most of developing countries. To assess the status of laboratory logistics management information system for HIV/AIDS and tuberculosis laboratory commodities in public health facilities in Addis Ababa. Methods A cross-sectional descriptive study was conducted from September 2010-January 2011 at selected public health facilities. A stratified random sampling method was used to include a total of 43 facilities which, were investigated through quantitative methods using structured questionnaires interviews. Focus group discussion with the designated supply chain managers and key informant interviews were conducted for the qualitative method. Results There exists a well-designed logistics system for laboratory commodities with trained pharmacy personnel, distributed standard LMIS formats and established inventory control procedures. However, majority of laboratory professionals were not trained in LMIS. Majority of the facilities (60.5%) were stocked out for at least one ART monitoring and TB laboratory reagents and the highest stock out rate was for chemistry reagents. Expired ART monitoring laboratory commodities were found in 25 (73.5%) of facilities. Fifty percent (50%) of the assessed hospitals and 54% of health centers were currently using stock/bin cards for all HIV/AIDS and TB laboratory commodities in main pharmacy store, among these only 25% and 20.8% of them were updated with accurate information matching with the physical count done at the time of visit for hospitals and health centers respectively. Conclusion Even though there exists a well designed laboratory LMIS, keeping quality stock/bin cards and LMIS reports were very low. Key ART monitoring laboratory commodities were stock out at many facilities at the day of visit and during the past six months. Based on findings, training of laboratory personnel's managing laboratory commodities and keeping

  6. The Effects of Computerized Clinical Decision Support Systems on Laboratory Test Ordering: A Systematic Review.

    Science.gov (United States)

    Delvaux, Nicolas; Van Thienen, Katrien; Heselmans, Annemie; de Velde, Stijn Van; Ramaekers, Dirk; Aertgeerts, Bert

    2017-04-01

    - Inappropriate laboratory test ordering has been shown to be as high as 30%. This can have an important impact on quality of care and costs because of downstream consequences such as additional diagnostics, repeat testing, imaging, prescriptions, surgeries, or hospital stays. - To evaluate the effect of computerized clinical decision support systems on appropriateness of laboratory test ordering. - We used MEDLINE, Embase, CINAHL, MEDLINE In-Process and Other Non-Indexed Citations, Clinicaltrials.gov, Cochrane Library, and Inspec through December 2015. Investigators independently screened articles to identify randomized trials that assessed a computerized clinical decision support system aimed at improving laboratory test ordering by providing patient-specific information, delivered in the form of an on-screen management option, reminder, or suggestion through a computerized physician order entry using a rule-based or algorithm-based system relying on an evidence-based knowledge resource. Investigators extracted data from 30 papers about study design, various study characteristics, study setting, various intervention characteristics, involvement of the software developers in the evaluation of the computerized clinical decision support system, outcome types, and various outcome characteristics. - Because of heterogeneity of systems and settings, pooled estimates of effect could not be made. Data showed that computerized clinical decision support systems had little or no effect on clinical outcomes but some effect on compliance. Computerized clinical decision support systems targeted at laboratory test ordering for multiple conditions appear to be more effective than those targeted at a single condition.

  7. Clinical significance of laboratory errors in patients with systemic lupus erythematosus

    Directory of Open Access Journals (Sweden)

    N.G. Klyukvina

    2014-01-01

    Full Text Available Laboratory examination is an integral part of managing patients with systemic lupus erythematosus (SLE. A number of laboratory tests need to be conducted to verify the diagnosis; some indicators attest to the development of a concomitant pathology (development of comorbid conditions and therapeutic aggravation. The monitoring of individual laboratory tests makes it possible to assess the effectiveness of therapy or indicates that it needs to be enhanced in some cases. Furthermore, some parameters are considered to be prognostic factors of treatment outcome. The article reports on the range and frequency of laboratory errors in SLE patients. The role of laboratory tests in diagnosis and assessment of disease prognosis is discussed. The relationship between clinical and laboratory manifestations and the mechanisms for preventing laboratory errors are studied. The international guidelines for monitoring SLE patients are presented. Proper range of examination of SLE patients and interpretation of the results ensures timely diagnosis (sometimes at the early stage and allows one to avoid a hyperdiagnosis, to timely prescribe adequate therapy, and prevent its complications. 

  8. Pre-Ebola virus disease laboratory system and related challenges in Liberia

    Directory of Open Access Journals (Sweden)

    Stephen B. Kennedy

    2016-10-01

    Full Text Available Prior to the Ebola virus disease outbreak in Liberia, the laboratory system was duplicativefragmented and minimally coordinated. The National Reference Laboratory was conceptualisedto address the existing challenges by promoting the implementation of effective and sustainablelaboratory services in Liberia. However, in a resource-limited environment such as Liberiaprogress regarding the rebuilding of the health system can be relatively slow, while efforts tosustain the transient gains remain a key challenge for the Ministry of Health. In this paper, wedescribe the pre-Ebola virus disease laboratory system in Liberia and its prevailing efforts toaddress future emerging infectious diseases, as well as current Infectious diseases, all of whichare exacerbated by poverty. We conclude that laboratory and diagnostic services in Liberiahave encountered numerous challenges regarding its efforts to strengthen the healthcaredelivery system. These challenges include limited trained human resource capacity, inadequateinfrastructure, and a lack of coordination. As with most countries in sub-Saharan Africa, whencomparing urban and rural settings, diagnostic and clinical services are generally skewedtoward urban health facilities and private, faith-based health facilities. We recommend thatstructured policy be directed at these challenges for national institutions to develop guidelinesto improve, strengthen and sustain diagnostic and curative laboratory services to effectivelyaddress current infectious diseases and prepare for future emerging and re-emerging infectiousdiseases.

  9. Leaf LIMS: A Flexible Laboratory Information Management System with a Synthetic Biology Focus.

    Science.gov (United States)

    Craig, Thomas; Holland, Richard; D'Amore, Rosalinda; Johnson, James R; McCue, Hannah V; West, Anthony; Zulkower, Valentin; Tekotte, Hille; Cai, Yizhi; Swan, Daniel; Davey, Robert P; Hertz-Fowler, Christiane; Hall, Anthony; Caddick, Mark

    2017-12-15

    This paper presents Leaf LIMS, a flexible laboratory information management system (LIMS) designed to address the complexity of synthetic biology workflows. At the project's inception there was a lack of a LIMS designed specifically to address synthetic biology processes, with most systems focused on either next generation sequencing or biobanks and clinical sample handling. Leaf LIMS implements integrated project, item, and laboratory stock tracking, offering complete sample and construct genealogy, materials and lot tracking, and modular assay data capture. Hence, it enables highly configurable task-based workflows and supports data capture from project inception to completion. As such, in addition to it supporting synthetic biology it is ideal for many laboratory environments with multiple projects and users. The system is deployed as a web application through Docker and is provided under a permissive MIT license. It is freely available for download at https://leaflims.github.io .

  10. Quality management systems for your in vitro fertilization clinic′s laboratory: Why bother?

    Directory of Open Access Journals (Sweden)

    Jan I Olofsson

    2013-01-01

    Full Text Available Several countries have in recent years introduced prescribed requirements for treatment and monitoring of outcomes, as well as a licensing or accreditation requirement for in vitro fertilization (IVF clinics and their laboratories. It is commonplace for Assisted Reproductive Technology (ART laboratories to be required to have a quality control system. However, more effective Total Quality Management systems are now being implemented by an increasing number of ART clinics. In India, it is now a requirement to have a quality management system in order to be accredited and to help meet customer demand for improved delivery of ART services. This review contains the proceedings a quality management session at the Indian Fertility Experts Meet (IFEM 2010 and focuses on the creation of a patient-oriented best-in-class IVF laboratory.

  11. Quality management systems for your in vitro fertilization clinic's laboratory: Why bother?

    Science.gov (United States)

    Olofsson, Jan I; Banker, Manish R; Sjoblom, Late Peter

    2013-01-01

    Several countries have in recent years introduced prescribed requirements for treatment and monitoring of outcomes, as well as a licensing or accreditation requirement for in vitro fertilization (IVF) clinics and their laboratories. It is commonplace for Assisted Reproductive Technology (ART) laboratories to be required to have a quality control system. However, more effective Total Quality Management systems are now being implemented by an increasing number of ART clinics. In India, it is now a requirement to have a quality management system in order to be accredited and to help meet customer demand for improved delivery of ART services. This review contains the proceedings a quality management session at the Indian Fertility Experts Meet (IFEM) 2010 and focuses on the creation of a patient-oriented best-in-class IVF laboratory.

  12. Factors Influencing Laboratory Information System Effectiveness Through Strategic Planning in Shiraz Teaching Hospitals.

    Science.gov (United States)

    Bahador, Fateme; Sharifian, Roxana; Farhadi, Payam; Jafari, Abdosaleh; Nematolahi, Mohtram; Shokrpour, Nasrin

    This study aimed to develop and test a research model that examined 7effective factors on the effectiveness of laboratory information system (LIS) through strategic planning. This research was carried out on total laboratory staff, information technology staff, and laboratory managers in Shiraz (a city in the south of Iran) teaching hospitals by structural equation modeling approach in 2015. The results revealed that there was no significant positive relationship between decisions based on cost-benefit analysis and LIS functionality with LIS effectiveness, but there was a significant positive relationship between other factors and LIS effectiveness. As expected, high levels of strategic information system planning result in increasing LIS effectiveness. The results also showed that the relationship between cost-benefit analysis, LIS functionality, end-user involvement, and information technology-business alignment with strategic information system planning was significant and positive.

  13. Developing an Affordable and Portable Control Systems Laboratory Kit with a Raspberry Pi

    Directory of Open Access Journals (Sweden)

    Rebecca M. Reck

    2016-07-01

    Full Text Available Instructional laboratories are common in engineering programs. Instructional laboratories should evolve with technology and support the changes in higher education, like the increased popularity of online courses. In this study, an affordable and portable laboratory kit was designed to replace the expensive on-campus equipment for two control systems courses. The complete kit costs under $135 and weighs under 0.68 kilograms. It is comprised of off-the-shelf components (e.g., Raspberry Pi, DC motor and 3D printed parts. The kit has two different configurations. The first (base configuration is a DC motor system with a position and speed sensor. The second configuration adds a Furuta inverted pendulum attachment with another position sensor. These configurations replicate most of the student learning outcomes for the two control systems courses for which they were designed.

  14. Assessing the outcome of Strengthening Laboratory Management Towards Accreditation (SLMTA) on laboratory quality management system in city government of Addis Ababa, Ethiopia

    Science.gov (United States)

    Sisay, Abay; Mindaye, Tedla; Tesfaye, Abrham; Abera, Eyob; Desale, Adino

    2015-01-01

    Introduction Strengthening Laboratory Management Toward Accreditation (SLMTA) is a competency-based management training programme designed to bring about immediate and measurable laboratory improvement. The aim of this study is to assess the outcome of SLMTA on laboratory quality management system in Addis Ababa, Ethiopia. Methods The study used an Institutional based cross sectional study design that employed a secondary and primary data collection approach on the participated institution of medical laboratory in SLMTA. The study was conducted in Addis Ababa city government and the data was collected from February ‘April 2014 and data was entered in to EPI-data version 3.1 and was analyzed by SPSS version 20. Results The assessment finding indicate that there was a significant improvement in average scores (141.4; range of 65-196, 95%CI =86.275-115.5, p = 0.000) at final with 3 laboratories become 3 star, 6 laboratories were at 2 star, 11 were 1 star. Laboratory facilities respondents which thought getting adequate and timely manner mentorship were found 2.5 times more likely to get good success in the final score(AOR= 2.501, 95% CI= 1.109-4.602) than which did not get it. Conclusion At the end of SLMTA implementation,3 laboratories score 3 star, 6 laboratories were at 2 star, 11 were at 1 star. The most important contributing factor for not scoring star in the final outcome of SLMTA were not conducting their customer satisfaction survey, poor staff motivation, and lack of regular equipment service maintenance. Mentorship, onsite and offsite coaching and training activities had shown a great improvement on laboratory quality management system in most laboratories. PMID:26175805

  15. Laboratory tests of overpressure differential systems for smoke protection of lobbies

    Science.gov (United States)

    Szałański, Paweł; Misiński, Jacek

    2017-11-01

    Paper presents the methodology of laboratory tests for ventilation overpressure differential systems for smoke protection of lobbies. Research area consists of two spaces representing the lobby and the area under fire equipped with proper ventilation installation. This allows testing of overpressure differential systems for smoke protection of lobbies. Moreover, piece of laboratory tests results for two selected smoke protection systems for lobbies are presented. First one is standard system with constantly opened transfer-damper mounted between lobby and area under fire. Second one - system with so called "electronic transfer" based on two dampers (supplying air to a lobby and to unprotected area alternatively). Opening and closing both dampers is electronically controlled. Changes of pressure difference between lobby and fire affected area during closing and opening doors between those spaces is presented. Conclusions, concerning the possibility of meeting the time period criteria of pressure difference stabilization required by standards, are presented and discussed for both systems.

  16. SOFTICE: Facilitating both Adoption of Linux Undergraduate Operating Systems Laboratories and Students' Immersion in Kernel Code

    Directory of Open Access Journals (Sweden)

    Alessio Gaspar

    2007-06-01

    Full Text Available This paper discusses how Linux clustering and virtual machine technologies can improve undergraduate students' hands-on experience in operating systems laboratories. Like similar projects, SOFTICE relies on User Mode Linux (UML to provide students with privileged access to a Linux system without creating security breaches on the hosting network. We extend such approaches in two aspects. First, we propose to facilitate adoption of Linux-based laboratories by using a load-balancing cluster made of recycled classroom PCs to remotely serve access to virtual machines. Secondly, we propose a new approach for students to interact with the kernel code.

  17. Research Applications and Capabilities of the NASA/Army Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL)

    Science.gov (United States)

    Aiken, Edwin W.; Jacobsen, Robert A.; Hindson, William S.

    1996-01-01

    The Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL) is a UH-60 Black Hawk helicopter that is being modified by NASA and the US Army for flight systems research. The principal systems that are being installed in the aircraft are a Helmet-Mounted Display (HMD) and associated imaging systems, and a programmable full-authority Research Flight Control System (RFCS). In addition, comprehensive instrumentation of both the rigid body of the helicopter and the rotor system is provided. This paper describes the design features of this modern rotorcraft in-flight simulation facility and their current state of development. A brief description of initial research applications is included.

  18. APPLICATION OF A PLC TO A LABORATORY COMPRESSOR WORKSHOP CONTROL SYSTEM

    Directory of Open Access Journals (Sweden)

    Wojciech GÓRA

    2016-06-01

    Full Text Available In this paper a control system of air compressors in a university laboratory is presented. The control system, which is built using the Astraada RCC972 and the GE 90-20 drivers, is an extension of the two states’ inputs and outputs of Astraada. To visualize the work stand, the PC computer class and the Proficy Machine Edition (ME View software were applied. Selected results from the tests of the built control system are presented.

  19. Sistema laboratorial de fracionamento de carboidratos de concentrados energéticos = Laboratorial system of carbohydrate fractions of energetic concentrate

    Directory of Open Access Journals (Sweden)

    Raquel Franco de Lima

    2006-04-01

    Full Text Available O objetivo deste estudo foi avaliar um sistema laboratorial de fracionamento para carboidratos para identificar e quantificar as frações que compõem esse nutriente em grãos e subprodutos. Foram determinadas as frações: açúcares simples (AS pelo método colorimétrico fenol-sulfúrico; amido disponível (AD e amido resistente (AR por digestões enzimáticas; fibra total (FT pelo método enzímico-gravimétrico; fibra em detergente neutro (FDN e fibra solúvel (FS, estimada pela diferença FT-FDN dos grãos de milho e sorgo, polpa de citrus, farelo de trigo, triguilho e farelo de arroz integral. Os coeficientes de variação para as frações AS, AD, AR, FT e FDN variaram de 4,81% a 19,17%; 4,58% a 15,03%; 2,42% a 9,91%; 1,23% a 8,23% e 1,16% a 8,42%, respectivamente, caracterizando uma boa repetibilidade das técnicas adotadas. O fracionamento identificou os principais grupos de carboidratos que compõem os alimentos e pode servir de referência para trabalhos futuros.The aim of this work was to evaluate a laboratorial system of carbohydrate fractions to identify and quantify the fractions that compose this nutrient. The following fractions were determined: simple sugars (SS using the colorimetric phenol-sulfuric method; digestible starch (DS and resistant starch (RS by enzymatic digestions; total fiber (TF using the enzymic-gravimetric method; neutral detergent fiber (NDF and soluble fiber (SF estimated by difference TF - NDF, in grains of corn and sorghum, citric pulp, wheat middlings, wheat mills and rice bran. The coefficient of variation for fractions SS, DS, RS, TF and NDF varied from 4.81 to 19.17%; 4.58 to 15.03%; 2.42 to 9.91%; 1.23 to 8.23% and 1.16 to 8.42%; respectively. A good repeatability of the method used was observed. The fraction identified the main groups of carbohydrates composed on the food and it can be a reference to future works.

  20. Real-Time Microbiology Laboratory Surveillance System to Detect Abnormal Events and Emerging Infections, Marseille, France.

    Science.gov (United States)

    Abat, Cédric; Chaudet, Hervé; Colson, Philippe; Rolain, Jean-Marc; Raoult, Didier

    2015-08-01

    Infectious diseases are a major threat to humanity, and accurate surveillance is essential. We describe how to implement a laboratory data-based surveillance system in a clinical microbiology laboratory. Two historical Microsoft Excel databases were implemented. The data were then sorted and used to execute the following 2 surveillance systems in Excel: the Bacterial real-time Laboratory-based Surveillance System (BALYSES) for monitoring the number of patients infected with bacterial species isolated at least once in our laboratory during the study periodl and the Marseille Antibiotic Resistance Surveillance System (MARSS), which surveys the primary β-lactam resistance phenotypes for 15 selected bacterial species. The first historical database contained 174,853 identifications of bacteria, and the second contained 12,062 results of antibiotic susceptibility testing. From May 21, 2013, through June 4, 2014, BALYSES and MARSS enabled the detection of 52 abnormal events for 24 bacterial species, leading to 19 official reports. This system is currently being refined and improved.

  1. Hardware flexibility of laboratory automation systems: analysis and new flexible automation architectures.

    Science.gov (United States)

    Najmabadi, Peyman; Goldenberg, Andrew A; Emili, Andrew

    2007-03-01

    Development of flexible laboratory automation systems has attracted tremendous attention in recent years as biotechnology scientists perform diverse types of protocols and tend to continuously modify them as part of their research. This article is a system level study of hardware flexibility of laboratory automation architectures for high-throughput automation of various sample preparation protocols. Hardware flexibility (system components' adaptability to protocol variations) of automation systems is addressed through the introduction of three main parametric flexibility measures functional, structural, and throughput. A new quantitative measurement method for these parameters in the realm of the Axiomatic Theory is introduced in this article. The method relies on defining probability of success functions for flexibility parameters and calculating their information contents. As flexibility information content decreases, automation system flexibility increases.

  2. The technical and economic feasibility of establishing a building system integration laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Crawley, D.B.; Drost, M.K.; Johnson, B.M.

    1989-09-01

    On December 22, 1987, the US Congress provided funding to the US Department of Energy (DOE) to study the feasibility and conceptual design of a whole building system integration laboratory'' (Title II of Pub. L. 100--202). A whole-building system integration laboratory would be a full-scale experimental facility in which the energy performance interactions of two or more building components, e.g., walls, windows, lighting, could be tested under actual operating conditions. At DOE's request, the Pacific Northwest Laboratory (PNL) conducted the study with the assistance of a technical review and representing other federal agencies and the academic and private sectors, including professional societies, building component manufacturers, and building research organizations. The results of the feasibility study are presented in this report.

  3. Inter-laboratory comparison of three earplug fit-test systems.

    Science.gov (United States)

    Byrne, David C; Murphy, William J; Krieg, Edward F; Ghent, Robert M; Michael, Kevin L; Stefanson, Earl W; Ahroon, William A

    2017-04-01

    The National Institute for Occupational Safety and Health (NIOSH) sponsored tests of three earplug fit-test systems (NIOSH HPD Well-Fit, Michael & Associates FitCheck, and Honeywell Safety Products VeriPRO). Each system was compared to laboratory-based real-ear attenuation at threshold (REAT) measurements in a sound field according to ANSI/ASA S12.6-2008 at the NIOSH, Honeywell Safety Products, and Michael & Associates testing laboratories. An identical study was conducted independently at the U.S. Army Aeromedical Research Laboratory (USAARL), which provided their data for inclusion in this article. The Howard Leight Airsoft premolded earplug was tested with twenty subjects at each of the four participating laboratories. The occluded fit of the earplug was maintained during testing with a soundfield-based laboratory REAT system as well as all three headphone-based fit-test systems. The Michael & Associates lab had the highest average A-weighted attenuations and smallest standard deviations. The NIOSH lab had the lowest average attenuations and the largest standard deviations. Differences in octave-band attenuations between each fit-test system and the American National Standards Institute (ANSI) sound field method were calculated (Attenfit-test - AttenANSI). A-weighted attenuations measured with FitCheck and HPD Well-Fit systems demonstrated approximately ±2 dB agreement with the ANSI sound field method, but A-weighted attenuations measured with the VeriPRO system underestimated the ANSI laboratory attenuations. For each of the fit-test systems, the average A-weighted attenuation across the four laboratories was not significantly greater than the average of the ANSI sound field method. Standard deviations for residual attenuation differences were about ±2 dB for FitCheck and HPD Well-Fit compared to ±4 dB for VeriPRO. Individual labs exhibited a range of agreement from less than a dB to as much as 9.4 dB difference with ANSI and REAT estimates. Factors such

  4. Experimental Bleaching of a Reef-Building Coral Using a Simplified Recirculating Laboratory Exposure System

    Science.gov (United States)

    Determining stressor-response relationships in reef building corals is a critical need for researchers because of global declines in coral reef ecosystems. A simplified recirculating coral exposure system for laboratory testing of a diversity of species and morphologies of reef b...

  5. A Simple System for Observing Dynamic Phase Equilibrium via an Inquiry-Based Laboratory or Demonstration

    Science.gov (United States)

    Cloonan, Carrie A.; Andrew, Julie A.; Nichol, Carolyn A.; Hutchinson, John S.

    2011-01-01

    This article describes an activity that can be used as an inquiry-based laboratory or demonstration for either high school or undergraduate chemistry students to provide a basis for understanding both vapor pressure and the concept of dynamic phase equilibrium. The activity includes a simple setup to create a closed system of only water liquid and…

  6. 78 FR 22536 - Procedural Manual for the Election Assistance Commission's Voting System Test Laboratories...

    Science.gov (United States)

    2013-04-16

    ... Manual, Version 2.0 AGENCY: United States Election Assistance Commission (EAC). ACTION: Notice; publication of Voting System Test Laboratories Program Manual, Version 2.0, for 60 day public comment period on EAC Web site. SUMMARY: The U.S. Election Assistance Commission (EAC) is publishing a procedural...

  7. An Embedded Systems Laboratory to Support Rapid Prototyping of Robotics and the Internet of Things

    Science.gov (United States)

    Hamblen, J. O.; van Bekkum, G. M. E.

    2013-01-01

    This paper describes a new approach for a course and laboratory designed to allow students to develop low-cost prototypes of robotic and other embedded devices that feature Internet connectivity, I/O, networking, a real-time operating system (RTOS), and object-oriented C/C++. The application programming interface (API) libraries provided permit…

  8. Road Transportable Analytical Laboratory (RTAL) system: Volume II, Appendices A and B. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Finger, S.M.; De Avila, J.C.; Keith, V.F.

    1996-08-01

    The Road Transportable Analytical Laboratory (RTAL) provides a portable analytical system for the analysis of soils, ground water, and surface water for the detection of hazardous materials, metals, organics, and radioactive material. This report presents the data results for an aqueous sample VOA report and an aqueous sample SVOA report.

  9. [Clinical governance and patient safety culture in clinical laboratories in the Spanish National Health System].

    Science.gov (United States)

    Giménez-Marín, Á; Rivas-Ruiz, F

    To conduct a situational analysis of patient safety culture in public laboratories in the Spanish National Health System and to determine the clinical governance variables that most strongly influence patient safety. A descriptive cross-sectional study was carried out, in which a Survey of Patient Safety in Clinical Laboratories was addressed to workers in 26 participating laboratories. In this survey, which consisted of 45 items grouped into 6 areas, scores were assigned on a scale from 0 to 100 (where 0 is the lowest perception of patient safety). Laboratory managers were asked specific questions about quality management systems and technology. The mean scores for the 26 participating hospitals were evaluated, and the following results observed: in 4of the 6areas, the mean score was higher than 70 points. In the third area (equipment and resources) and the fourth area (working conditions), the scores were lower than 60 points. Every hospital had a digital medical record system. This 100% level of provision was followed by that of an electronic request management system, which was implemented in 82.6% of the hospitals. The results obtained show that the culture of security is homogeneous and of high quality in health service laboratories, probably due to the steady improvement observed. However, in terms of clinical governance, there is still some way to go, as shown by the presence of weaknesses in crucial dimensions of safety culture, together with variable levels of implementation of fail-safe technologies and quality management systems. Copyright © 2017 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. NASA Glenn Research Center's Fuel Cell Stack, Ancillary and System Test and Development Laboratory

    Science.gov (United States)

    Loyselle, Patricia L.; Prokopius, Kevin P.; Becks, Larry A.; Burger, Thomas H.; Dick, Joseph F.; Rodriguez, George; Bremenour, Frank; Long, Zedock

    2011-01-01

    At the NASA Glenn Research Center, a fully operational fuel cell test and evaluation laboratory is available which is capable of evaluating fuel cell components and systems for future NASA missions. Components and subsystems of various types can be operated and monitored under a variety of conditions utilizing different reactants. This fuel cell facility can test the effectiveness of various component and system designs to meet NASA's needs.

  11. RFID based Anti-theft System for Metropolia UAS Electronics laboratories

    OpenAIRE

    Weldemedhin, Desta

    2016-01-01

    The aim of this thesis is to study different types of RFID based anti-Theft system implementation suitable for Metropolia Electronics laboratory environment to deter theft taking into account several installation requirements. The operating frequencies of the RFID anti-theft system are from low frequency to High frequencies range and governed by different standards based on the region it is going to be implemented. The introduction of this thesis will go through Radio Frequency Identifica...

  12. Isotopic power supplies for space and terrestrial systems: quality assurance by Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Hannigan, R.L.; Harnar, R.R.

    1981-09-01

    The Sandia National Laboratories participation in Quality Assurance (QA) programs for Radioisotopic Thermoelectric Generators which have been used in space and terrestrial systems over the past 15 years is summarized. Basic elements of the program are briefly described and recognition of assistance from other Sandia organizations is included. Descriptions of the various systems for which Sandia has had the QA responsibility are also presented. In addition, the outlook for Sandia participation in RTG programs for the next several years is noted.

  13. Develop virtual joint laboratory for education like distance engineering system for robotic applications

    Science.gov (United States)

    Latinovic, T. S.; Deaconu, S. I.; Latinović, M. T.; Malešević, N.; Barz, C.

    2015-06-01

    This paper work with a new system that provides distance learning and online training engineers. The purpose of this paper is to develop and provide web-based system for the handling and control of remote devices via the Internet. Remote devices are currently the industry or mobile robots [13]. For future product development machine in the factory will be included in the system. This article also discusses the current use of virtual reality tools in the fields of science and engineering education. One programming tool in particular, virtual reality modeling language (VRML) is presented in the light of its applications and capabilities in the development of computer visualization tool for education. One contribution of this paper is to present the software tools and examples that can encourage educators to develop a virtual reality model to improve teaching in their discipline. [12] This paper aims to introduce a software platform, called VALIP where users can build, share, and manipulate 3D content in cooperation with the interaction processes in a 3D context, while participating hardware and software devices can be physical and / or logical distributed and connected together via the Internet. VALIP the integration of virtual laboratories to appropriate partners; therefore, allowing access to all laboratories in any of the partners in the project. VALIP provides advanced laboratory for training and research within robotics and production engineering, and thus, provides a great laboratory facilities with only having to invest a limited amount of resources at the local level to the partner site.

  14. The implementation of a system for managing analytical quality in networked laboratories.

    Science.gov (United States)

    Jassam, Nuthar; Lindsay, Chris; Harrison, Kevin; Thompson, Douglas; Bosomworth, Mike P; Barth, Julian H

    2011-03-01

    In a network of laboratories analytical variability between instruments, even of the same type, may exist for reasons beyond the control of laboratory staff. Controlling variability is a prerequisite for the application of shared reference ranges and for ensuring the transferability of patient test results. Controlling variability requires a robust, non-conventional quality system to detect poor performance of analysers that are geographically distant. Essential to this quality system is a set of well-defined quality specifications. The approach used in our study started with (1) selection of a model for quality specifications based on biological variation; the 'three-level model' (TLM) was selected on the basis of its flexibility to accommodate various levels of analytical performance; (2) determination of the performance characteristics of the 71 analytes measured in core biochemistry in terms of imprecision and bias; (3) defining quality requirements in the form of imprecision, bias and total error for 71 analytes measured routinely in core biochemistry; and (4) developing software to assist a consistent wide application of the quality specifications and to monitor analytical indices to the common quality specifications. In this paper we describe how we have implemented this model across our network. Forty-six of the 71 analytes in our core laboratory repertoire were allocated to the TLM. We were able to demonstrate equivalence of results on all analysers, for 42 out of 46 analytes allocated to this model. We propose that other networked laboratories should investigate the suitability of this quality system for use in their network.

  15. Distributed Energy Technology Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Distributed Energy Technologies Laboratory (DETL) is an extension of the power electronics testing capabilities of the Photovoltaic System Evaluation Laboratory...

  16. Implementation of quality management systems and progress towards accreditation of National Tuberculosis Reference Laboratories in Africa

    Science.gov (United States)

    de Dieu Iragena, Jean; Kao, Kekeletso; Erni, Donatelle; Mekonen, Teferi

    2017-01-01

    Background Laboratory services are essential at all stages of the tuberculosis care cascade, from diagnosis and drug resistance testing to monitoring response to treatment. Enabling access to quality services is a challenge in low-resource settings. Implementation of a strong quality management system (QMS) and laboratory accreditation are key to improving patient care. Objectives The study objective was to determine the status of QMS implementation and progress towards accreditation of National Tuberculosis Reference Laboratories (NTRLs) in the African Region. Method An online questionnaire was administered to NTRL managers in 47 World Health Organization Regional Office for Africa member states in the region, between February and April 2015, regarding the knowledge of QMS tools and progress toward implementation to inform strategies for tuberculosis diagnostic services strengthening in the region. Results A total of 21 laboratories (43.0%) had received SLMTA/TB-SLMTA training, of which 10 had also used the Global Laboratory Initiative accreditation tool. However, only 36.7% of NTRLs had received a laboratory audit, a first step in quality improvement. Most NTRLs participated in acid-fast bacilli microscopy external quality assurance (95.8%), although external quality assurance for other techniques was lower (60.4% for first-line drug susceptibility testing, 25.0% for second-line drug susceptibility testing, and 22.9% for molecular testing). Barriers to accreditation included lack of training and accreditation programmes. Only 28.6% of NTRLs had developed strategic plans and budgets which included accreditation. Conclusion Good foundations are in place on the continent from which to scale up accreditation efforts. Laboratory audits should be conducted as a first step in developing quality improvement action plans. Political commitment and strong leadership are needed to drive accreditation efforts; advocacy will require clear evidence of patient impact and cost

  17. Implementation of quality management systems and progress towards accreditation of National Tuberculosis Reference Laboratories in Africa.

    Science.gov (United States)

    Albert, Heidi; de Dieu Iragena, Jean; Kao, Kekeletso; Erni, Donatelle; Mekonen, Teferi; Onyebujoh, Philip C

    2017-01-01

    Laboratory services are essential at all stages of the tuberculosis care cascade, from diagnosis and drug resistance testing to monitoring response to treatment. Enabling access to quality services is a challenge in low-resource settings. Implementation of a strong quality management system (QMS) and laboratory accreditation are key to improving patient care. The study objective was to determine the status of QMS implementation and progress towards accreditation of National Tuberculosis Reference Laboratories (NTRLs) in the African Region. An online questionnaire was administered to NTRL managers in 47 World Health Organization Regional Office for Africa member states in the region, between February and April 2015, regarding the knowledge of QMS tools and progress toward implementation to inform strategies for tuberculosis diagnostic services strengthening in the region. A total of 21 laboratories (43.0%) had received SLMTA/TB-SLMTA training, of which 10 had also used the Global Laboratory Initiative accreditation tool. However, only 36.7% of NTRLs had received a laboratory audit, a first step in quality improvement. Most NTRLs participated in acid-fast bacilli microscopy external quality assurance (95.8%), although external quality assurance for other techniques was lower (60.4% for first-line drug susceptibility testing, 25.0% for second-line drug susceptibility testing, and 22.9% for molecular testing). Barriers to accreditation included lack of training and accreditation programmes. Only 28.6% of NTRLs had developed strategic plans and budgets which included accreditation. Good foundations are in place on the continent from which to scale up accreditation efforts. Laboratory audits should be conducted as a first step in developing quality improvement action plans. Political commitment and strong leadership are needed to drive accreditation efforts; advocacy will require clear evidence of patient impact and cost-benefit.

  18. Cost evaluation of clinical laboratory in Taiwan's National Health System by using activity-based costing.

    Science.gov (United States)

    Su, Bin-Guang; Chen, Shao-Fen; Yeh, Shu-Hsing; Shih, Po-Wen; Lin, Ching-Chiang

    2016-11-01

    To cope with the government's policies to reduce medical costs, Taiwan's healthcare service providers are striving to survive by pursuing profit maximization through cost control. This article aimed to present the results of cost evaluation using activity-based costing performed in the laboratory in order to throw light on the differences between costs and the payment system of National Health Insurance (NHI). This study analyzed the data of costs and income of the clinical laboratory. Direct costs belong to their respective sections of the department. The department's shared costs, including public expenses and administrative assigned costs, were allocated to the department's respective sections. A simple regression equation was created to predict profit and loss, and evaluate the department's break-even point, fixed cost, and contribution margin ratio. In clinical chemistry and seroimmunology sections, the cost per test was lower than the NHI payment and their major laboratory tests had revenues with the profitability ratio of 8.7%, while the other sections had a higher cost per test than the NHI payment and their major tests were in deficit. The study found a simple linear regression model as follows: "Balance=-84,995+0.543×income (R2=0.544)". In order to avoid deficit, laboratories are suggested to increase test volumes, enhance laboratory test specialization, and become marginal scale. A hospital could integrate with regional medical institutions through alliances or OEM methods to increase volumes to reach marginal scale and reduce laboratory costs, enhancing the level and quality of laboratory medicine.

  19. Implementation of quality management systems and progress towards accreditation of National Tuberculosis Reference Laboratories in Africa

    Directory of Open Access Journals (Sweden)

    Heidi Albert

    2017-03-01

    Full Text Available Background: Laboratory services are essential at all stages of the tuberculosis care cascade, from diagnosis and drug resistance testing to monitoring response to treatment. Enabling access to quality services is a challenge in low-resource settings. Implementation of a strong quality management system (QMS and laboratory accreditation are key to improving patient care. Objectives: The study objective was to determine the status of QMS implementation and progress towards accreditation of National Tuberculosis Reference Laboratories (NTRLs in the African Region. Method: An online questionnaire was administered to NTRL managers in 47 World Health Organization Regional Office for Africa member states in the region, between February and April 2015, regarding the knowledge of QMS tools and progress toward implementation to inform strategies for tuberculosis diagnostic services strengthening in the region. Results: A total of 21 laboratories (43.0% had received SLMTA/TB-SLMTA training, of which 10 had also used the Global Laboratory Initiative accreditation tool. However, only 36.7% of NTRLs had received a laboratory audit, a first step in quality improvement. Most NTRLs participated in acid-fast bacilli microscopy external quality assurance (95.8%, although external quality assurance for other techniques was lower (60.4% for first-line drug susceptibility testing, 25.0% for second-line drug susceptibility testing, and 22.9% for molecular testing. Barriers to accreditation included lack of training and accreditation programmes. Only 28.6%of NTRLs had developed strategic plans and budgets which included accreditation. Conclusion: Good foundations are in place on the continent from which to scale up accreditation efforts. Laboratory audits should be conducted as a first step in developing quality improvement action plans. Political commitment and strong leadership are needed to drive accreditation efforts; advocacy will require clear evidence of patient

  20. Implementation of quality management systems and progress towards accreditation of National Tuberculosis Reference Laboratories in Africa

    Directory of Open Access Journals (Sweden)

    Heidi Albert

    2017-03-01

    Full Text Available Background: Laboratory services are essential at all stages of the tuberculosis care cascade, from diagnosis and drug resistance testing to monitoring response to treatment. Enabling access to quality services is a challenge in low-resource settings. Implementation of a strong quality management system (QMS and laboratory accreditation are key to improving patient care.Objectives: The study objective was to determine the status of QMS implementation and progress towards accreditation of National Tuberculosis Reference Laboratories (NTRLs in the African Region.Method: An online questionnaire was administered to NTRL managers in 47 World Health Organization Regional Office for Africa member states in the region, between February and April 2015, regarding the knowledge of QMS tools and progress toward implementation to inform strategies for tuberculosis diagnostic services strengthening in the region.Results: A total of 21 laboratories (43.0% had received SLMTA/TB-SLMTA training, of which 10 had also used the Global Laboratory Initiative accreditation tool. However, only 36.7% of NTRLs had received a laboratory audit, a first step in quality improvement. Most NTRLs participated in acid-fast bacilli microscopy external quality assurance (95.8%, although external quality assurance for other techniques was lower (60.4% for first-line drug susceptibility testing, 25.0% for second-line drug susceptibility testing, and 22.9% for molecular testing. Barriers to accreditation included lack of training and accreditation programmes. Only 28.6%of NTRLs had developed strategic plans and budgets which included accreditation.Conclusion: Good foundations are in place on the continent from which to scale up accreditation efforts. Laboratory audits should be conducted as a first step in developing quality improvement action plans. Political commitment and strong leadership are needed to drive accreditation efforts; advocacy will require clear evidence of patient

  1. Effects of earthquake induced rock shear on containment system integrity. Laboratory testing plan development

    Energy Technology Data Exchange (ETDEWEB)

    Read, Rodney S. (RSRead Consulting Inc. (Canada))

    2011-07-15

    This report describes a laboratory-scale testing program plan to address the issue of earthquake induced rock shear effects on containment system integrity. The document contains a review of relevant literature from SKB covering laboratory testing of bentonite clay buffer material, scaled analogue tests, and the development of related material models to simulate rock shear effects. The proposed testing program includes standard single component tests, new two-component constant volume tests, and new scaled analogue tests. Conceptual drawings of equipment required to undertake these tests are presented along with a schedule of tests. The information in this document is considered sufficient to engage qualified testing facilities, and to guide implementation of laboratory testing of rock shear effects. This document was completed as part of a collaborative agreement between SKB and Nuclear Waste Management Organization (NWMO) in Canada

  2. Implementation of Software Tools for Hybrid Control Rooms in the Human Systems Simulation Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Jokstad, Håkon [Halden Reactor Project, Halden (Norway); Berntsson, Olof [Halden Reactor Project, Halden (Norway); McDonald, Robert [Halden Reactor Project, Halden (Norway); Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Hallbert, Bruce [Idaho National Lab. (INL), Idaho Falls, ID (United States); Fitzgerald, Kirk [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-11-01

    The Institute for Energy Technology (IFE) and Idaho National Laboratory have designed, implemented, tested and installed a functioning prototype of a set of large screen overview and procedure support displays for the Generic Pressurized Water Reactor (GPWR) simulator in the U.S. Department of Energy’s Human Systems Simulation Laboratory. The overview display is based on IFE’s extensive experiences with large screen overview displays in the Halden Man-Machine Laboratory (HAMMLAB), and presents the main control room indicators on a combined three-screen display. The procedure support displays are designed and implemented to provide a compact but still comprehensive overview of the relevant process measurements and indicators to support operators' good situational awareness during the performance of various types of procedures and plant conditions.

  3. An integrated user-oriented laboratory for verification of digital flight control systems: Features and capabilities

    Science.gov (United States)

    Defeo, P.; Doane, D.; Saito, J.

    1982-01-01

    A Digital Flight Control Systems Verification Laboratory (DFCSVL) has been established at NASA Ames Research Center. This report describes the major elements of the laboratory, the research activities that can be supported in the area of verification and validation of digital flight control systems (DFCS), and the operating scenarios within which these activities can be carried out. The DFCSVL consists of a palletized dual-dual flight-control system linked to a dedicated PDP-11/60 processor. Major software support programs are hosted in a remotely located UNIVAC 1100 accessible from the PDP-11/60 through a modem link. Important features of the DFCSVL include extensive hardware and software fault insertion capabilities, a real-time closed loop environment to exercise the DFCS, an integrated set of software verification tools, and a user-oriented interface to all the resources and capabilities.

  4. Validating the Technology Acceptance Model in the Context of the Laboratory Information System-Electronic Health Record Interface System

    Science.gov (United States)

    Aquino, Cesar A.

    2014-01-01

    This study represents a research validating the efficacy of Davis' Technology Acceptance Model (TAM) by pairing it with the Organizational Change Readiness Theory (OCRT) to develop another extension to the TAM, using the medical Laboratory Information Systems (LIS)--Electronic Health Records (EHR) interface as the medium. The TAM posits that it is…

  5. Visualization Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Evaluates and improves the operational effectiveness of existing and emerging electronic warfare systems. By analyzing and visualizing simulation results...

  6. EPR (Electronic Patient Record Laboratory - Simulated Environment to Learn about a Hospital EPR System

    Directory of Open Access Journals (Sweden)

    Kazuko Yamamoto

    2011-03-01

    Full Text Available The “Electronic Patient Record (EPR Laboratory” is a computer based self-learning system developed for students to acquire practical skills and knowledge required to deal with EPRs. The system is designed to supplement conventional lectures on health information systems given as part of our undergraduate curriculum. Using the Laboratory, the students may learn not only operations of EPR systems but also the subjects connected with patient information handling, including privacy, security and health information ethics. The EPR Laboratory is composed of an eLearing system and an EPR system. The learning materials are arranged in units in the eLearning system, and in each unit, the student learns the materials and the EPR operations through practice. Tests are given at each end of unit, and if a student failed a test, the system shows which questions were answered incorrectly and indicates which parts of the unit he/she should review. For this purpose, we introduced a structure to the learning materials based on an information model. In this paper, the overview of the system, the simulated environment to learn patient flow, information flow and hospital workflow, fundamental EPR operations, and structured learning materials for the test and review cycle are described.

  7. An Experimental Study of Laboratory Hybrid Power System with the Hydrogen Technologies

    Directory of Open Access Journals (Sweden)

    Daniel Minarik

    2014-01-01

    Full Text Available This paper presents very small laboratory hybrid photovoltaic-hydrogen power system. The system was primarily assembled to verify the operability of the control algorithms and practical deployment of available commercial hydrogen technologies that are directly usable for storage of electricity produced from renewable energy sources in a small island system. This energetic system was installed and tested in Laboratory of fuel cells that is located in the university campus of VSB-Technical University of Ostrava. The energetic system consists of several basic components: a photovoltaic field, accumulators bank, water commercial electrolyzer and compact fuel cell system. The weather conditions recorded in two different weeks as model weather and solar conditions are used as case studies to test the energetic system and the results for two different cases are compared each other. The results show and illustrate selected behaviour curves of the power system and also average energy storage efficiency for accumulation subsystem based on hydrogen technologies or at the energetic system embedded components. On the basis of real measurement and its evaluation the ideal parameters of the photovoltaic field were calculated as well as the hydrogen technologies for supposed purpose and the power requirements.

  8. The EnzymeTracker: an open-source laboratory information management system for sample tracking.

    Science.gov (United States)

    Triplet, Thomas; Butler, Gregory

    2012-01-26

    In many laboratories, researchers store experimental data on their own workstation using spreadsheets. However, this approach poses a number of problems, ranging from sharing issues to inefficient data-mining. Standard spreadsheets are also error-prone, as data do not undergo any validation process. To overcome spreadsheets inherent limitations, a number of proprietary systems have been developed, which laboratories need to pay expensive license fees for. Those costs are usually prohibitive for most laboratories and prevent scientists from benefiting from more sophisticated data management systems. In this paper, we propose the EnzymeTracker, a web-based laboratory information management system for sample tracking, as an open-source and flexible alternative that aims at facilitating entry, mining and sharing of experimental biological data. The EnzymeTracker features online spreadsheets and tools for monitoring numerous experiments conducted by several collaborators to identify and characterize samples. It also provides libraries of shared data such as protocols, and administration tools for data access control using OpenID and user/team management. Our system relies on a database management system for efficient data indexing and management and a user-friendly AJAX interface that can be accessed over the Internet. The EnzymeTracker facilitates data entry by dynamically suggesting entries and providing smart data-mining tools to effectively retrieve data. Our system features a number of tools to visualize and annotate experimental data, and export highly customizable reports. It also supports QR matrix barcoding to facilitate sample tracking. The EnzymeTracker was designed to be easy to use and offers many benefits over spreadsheets, thus presenting the characteristics required to facilitate acceptance by the scientific community. It has been successfully used for 20 months on a daily basis by over 50 scientists. The EnzymeTracker is freely available online at http

  9. The EnzymeTracker: an open-source laboratory information management system for sample tracking

    Directory of Open Access Journals (Sweden)

    Triplet Thomas

    2012-01-01

    Full Text Available Abstract Background In many laboratories, researchers store experimental data on their own workstation using spreadsheets. However, this approach poses a number of problems, ranging from sharing issues to inefficient data-mining. Standard spreadsheets are also error-prone, as data do not undergo any validation process. To overcome spreadsheets inherent limitations, a number of proprietary systems have been developed, which laboratories need to pay expensive license fees for. Those costs are usually prohibitive for most laboratories and prevent scientists from benefiting from more sophisticated data management systems. Results In this paper, we propose the EnzymeTracker, a web-based laboratory information management system for sample tracking, as an open-source and flexible alternative that aims at facilitating entry, mining and sharing of experimental biological data. The EnzymeTracker features online spreadsheets and tools for monitoring numerous experiments conducted by several collaborators to identify and characterize samples. It also provides libraries of shared data such as protocols, and administration tools for data access control using OpenID and user/team management. Our system relies on a database management system for efficient data indexing and management and a user-friendly AJAX interface that can be accessed over the Internet. The EnzymeTracker facilitates data entry by dynamically suggesting entries and providing smart data-mining tools to effectively retrieve data. Our system features a number of tools to visualize and annotate experimental data, and export highly customizable reports. It also supports QR matrix barcoding to facilitate sample tracking. Conclusions The EnzymeTracker was designed to be easy to use and offers many benefits over spreadsheets, thus presenting the characteristics required to facilitate acceptance by the scientific community. It has been successfully used for 20 months on a daily basis by over 50

  10. DB4US: A Decision Support System for Laboratory Information Management

    Science.gov (United States)

    Hortas, Maria Luisa; Baena-García, Manuel; Lana-Linati, Jorge; González, Carlos; Redondo, Maximino; Morales-Bueno, Rafael

    2012-01-01

    Background Until recently, laboratory automation has focused primarily on improving hardware. Future advances are concentrated on intelligent software since laboratories performing clinical diagnostic testing require improved information systems to address their data processing needs. In this paper, we propose DB4US, an application that automates information related to laboratory quality indicators information. Currently, there is a lack of ready-to-use management quality measures. This application addresses this deficiency through the extraction, consolidation, statistical analysis, and visualization of data related to the use of demographics, reagents, and turn-around times. The design and implementation issues, as well as the technologies used for the implementation of this system, are discussed in this paper. Objective To develop a general methodology that integrates the computation of ready-to-use management quality measures and a dashboard to easily analyze the overall performance of a laboratory, as well as automatically detect anomalies or errors. The novelty of our approach lies in the application of integrated web-based dashboards as an information management system in hospital laboratories. Methods We propose a new methodology for laboratory information management based on the extraction, consolidation, statistical analysis, and visualization of data related to demographics, reagents, and turn-around times, offering a dashboard-like user web interface to the laboratory manager. The methodology comprises a unified data warehouse that stores and consolidates multidimensional data from different data sources. The methodology is illustrated through the implementation and validation of DB4US, a novel web application based on this methodology that constructs an interface to obtain ready-to-use indicators, and offers the possibility to drill down from high-level metrics to more detailed summaries. The offered indicators are calculated beforehand so that they

  11. DB4US: A Decision Support System for Laboratory Information Management.

    Science.gov (United States)

    Carmona-Cejudo, José M; Hortas, Maria Luisa; Baena-García, Manuel; Lana-Linati, Jorge; González, Carlos; Redondo, Maximino; Morales-Bueno, Rafael

    2012-11-14

    Until recently, laboratory automation has focused primarily on improving hardware. Future advances are concentrated on intelligent software since laboratories performing clinical diagnostic testing require improved information systems to address their data processing needs. In this paper, we propose DB4US, an application that automates information related to laboratory quality indicators information. Currently, there is a lack of ready-to-use management quality measures. This application addresses this deficiency through the extraction, consolidation, statistical analysis, and visualization of data related to the use of demographics, reagents, and turn-around times. The design and implementation issues, as well as the technologies used for the implementation of this system, are discussed in this paper. To develop a general methodology that integrates the computation of ready-to-use management quality measures and a dashboard to easily analyze the overall performance of a laboratory, as well as automatically detect anomalies or errors. The novelty of our approach lies in the application of integrated web-based dashboards as an information management system in hospital laboratories. We propose a new methodology for laboratory information management based on the extraction, consolidation, statistical analysis, and visualization of data related to demographics, reagents, and turn-around times, offering a dashboard-like user web interface to the laboratory manager. The methodology comprises a unified data warehouse that stores and consolidates multidimensional data from different data sources. The methodology is illustrated through the implementation and validation of DB4US, a novel web application based on this methodology that constructs an interface to obtain ready-to-use indicators, and offers the possibility to drill down from high-level metrics to more detailed summaries. The offered indicators are calculated beforehand so that they are ready to use when the user

  12. Design and implementation of an online systemic human anatomy course with laboratory.

    Science.gov (United States)

    Attardi, Stefanie M; Rogers, Kem A

    2015-01-01

    Systemic Human Anatomy is a full credit, upper year undergraduate course with a (prosection) laboratory component at Western University Canada. To meet enrollment demands beyond the physical space of the laboratory facility, a fully online section was developed to run concurrently with the traditional face to face (F2F) course. Lectures given to F2F students are simultaneously broadcasted to online students using collaborative software (Blackboard Collaborate). The same collaborative software is used by a teaching assistant to deliver laboratory demonstrations in which three-dimensional (3D) virtual anatomical models are manipulated. Ten commercial software programs were reviewed to determine their suitability for demonstrating the virtual models, resulting in the selection of Netter's 3D Interactive Anatomy. Supplementary online materials for the central nervous system were developed by creating 360° images of plastinated prosected brain specimens and a website through which they could be accessed. This is the first description of a fully online undergraduate anatomy course with a live, interactive laboratory component. Preliminary data comparing the online and F2F student grades suggest that previous student academic performance, and not course delivery format, predicts performance in anatomy. Future qualitative studies will reveal student perceptions about their learning experiences in both of the course delivery formats. © 2014 American Association of Anatomists.

  13. Importance of implementing an analytical quality control system in a core laboratory.

    Science.gov (United States)

    Marques-Garcia, F; Garcia-Codesal, M F; Caro-Narros, M R; Contreras-SanFeliciano, T

    2015-01-01

    The aim of the clinical laboratory is to provide useful information for screening, diagnosis and monitoring of disease. The laboratory should ensure the quality of extra-analytical and analytical process, based on set criteria. To do this, it develops and implements a system of internal quality control, designed to detect errors, and compare its data with other laboratories, through external quality control. In this way it has a tool to detect the fulfillment of the objectives set, and in case of errors, allowing corrective actions to be made, and ensure the reliability of the results. This article sets out to describe the design and implementation of an internal quality control protocol, as well as its periodical assessment intervals (6 months) to determine compliance with pre-determined specifications (Stockholm Consensus(1)). A total of 40 biochemical and 15 immunochemical methods were evaluated using three different control materials. Next, a standard operation procedure was planned to develop a system of internal quality control that included calculating the error of the analytical process, setting quality specifications, and verifying compliance. The quality control data were then statistically depicted as means, standard deviations, and coefficients of variation, as well as systematic, random, and total errors. The quality specifications were then fixed and the operational rules to apply in the analytical process were calculated. Finally, our data were compared with those of other laboratories through an external quality assurance program. The development of an analytical quality control system is a highly structured process. This should be designed to detect errors that compromise the stability of the analytical process. The laboratory should review its quality indicators, systematic, random and total error at regular intervals, in order to ensure that they are meeting pre-determined specifications, and if not, apply the appropriate corrective actions

  14. Design demonstrations for category B tank systems at Oak Ridge National Laboratory, Oak Ridge, Tennessee

    Energy Technology Data Exchange (ETDEWEB)

    1994-11-01

    This document presents design demonstrations conducted of liquid low-level waste (LLLW) storage tank systems located at the Oak Ridge National Laboratory (ORNL). Demonstration of the design of these tank systems has been stipulated by the Federal Facility Agreement (FFA) between the US Environmental Protection Agency (EPA)-Region IV; the Tennessee Department of Environment and Conservation (TDEC); and the DOE. The FFA establishes four categories of tanks. These are: Category A -- New or replacement tank systems with secondary containment; Category B -- Existing tank systems with secondary containment; Category C -- Existing tank systems without secondary containment; Category D -- Existing tank systems without secondary containment that are removed from service. This document provides a design demonstration of the secondary containment and ancillary equipment of 11 tank systems listed in the FFA as Category B. The design demonstration for each tank is presented.

  15. Survey of biomedical and environental data bases, models, and integrated computer systems at Argonne National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Murarka, I.P.; Bodeau, D.J.; Scott, J.M.; Huebner, R.H.

    1978-08-01

    This document contains an inventory (index) of information resources pertaining to biomedical and environmental projects at Argonne National Laboratory--the information resources include a data base, model, or integrated computer system. Entries are categorized as models, numeric data bases, bibliographic data bases, or integrated hardware/software systems. Descriptions of the Information Coordination Focal Point (ICFP) program, the system for compiling this inventory, and the plans for continuing and expanding it are given, and suggestions for utilizing the services of the ICFP are outlined.

  16. Motion control system of MAX IV Laboratory soft x-ray beamlines

    Energy Technology Data Exchange (ETDEWEB)

    Sjöblom, Peter, E-mail: peter.sjoblom@maxlab.lu.se; Lindberg, Mirjam, E-mail: mirjam.lindberg@maxlab.lu.se; Forsberg, Johan, E-mail: johan.forsberg@maxlab.lu.se; Persson, Andreas G., E-mail: andreas-g.persson@maxlab.lu.se; Urpelainen, Samuli, E-mail: samuli.urpelainen@maxlab.lu.se; Såthe, Conny, E-mail: conny.sathe@maxlab.lu.se [MAX IV Laboratory, Photongatan 2, 225 92 Lund (Sweden)

    2016-07-27

    At the MAX IV Laboratory, five new soft x-ray beamlines are under development. The first is Species and it will be used to develop and set the standard of the control system, which will be common across the facility. All motion axes at MAX IV will be motorized using stepper motors steered by the IcePAP motion controller and a mixture of absolute and incremental encoders following a predefined coordinate system. The control system software is built in Tango and uses the Python-based Sardana framework. The user controls the entire beamline through a synoptic overview and Sardana is used to run the scans.

  17. Establishing Ebola Virus Disease (EVD) diagnostics using GeneXpert technology at a mobile laboratory in Liberia: Impact on outbreak response, case management and laboratory systems strengthening.

    Science.gov (United States)

    Raftery, Philomena; Condell, Orla; Wasunna, Christine; Kpaka, Jonathan; Zwizwai, Ruth; Nuha, Mahmood; Fallah, Mosoka; Freeman, Maxwell; Harris, Victoria; Miller, Mark; Baller, April; Massaquoi, Moses; Katawera, Victoria; Saindon, John; Bemah, Philip; Hamblion, Esther; Castle, Evelyn; Williams, Desmond; Gasasira, Alex; Nyenswah, Tolbert

    2018-01-01

    The 2014-16 Ebola Virus Disease (EVD) outbreak in West Africa highlighted the necessity for readily available, accurate and rapid diagnostics. The magnitude of the outbreak and the re-emergence of clusters of EVD cases following the declaration of interrupted transmission in Liberia, reinforced the need for sustained diagnostics to support surveillance and emergency preparedness. We describe implementation of the Xpert Ebola Assay, a rapid molecular diagnostic test run on the GeneXpert platform, at a mobile laboratory in Liberia and the subsequent impact on EVD outbreak response, case management and laboratory system strengthening. During the period of operation, site coordination, management and operational capacity was supported through a successful collaboration between Ministry of Health (MoH), World Health Organization (WHO) and international partners. A team of Liberian laboratory technicians were trained to conduct EVD diagnostics and the laboratory had capacity to test 64-100 blood specimens per day. Establishment of the laboratory significantly increased the daily testing capacity for EVD in Liberia, from 180 to 250 specimens at a time when the effectiveness of the surveillance system was threatened by insufficient diagnostic capacity. During the 18 months of operation, the laboratory tested a total of 9,063 blood specimens, including 21 EVD positives from six confirmed cases during two outbreaks. Following clearance of the significant backlog of untested EVD specimens in November 2015, a new cluster of EVD cases was detected at the laboratory. Collaboration between surveillance and laboratory coordination teams during this and a later outbreak in March 2016, facilitated timely and targeted response interventions. Specimens taken from cases during both outbreaks were analysed at the laboratory with results informing clinical management of patients and discharge decisions. The GeneXpert platform is easy to use, has relatively low running costs and can be

  18. Initial experimental results from the Laboratory Biosphere closed ecological system facility

    Science.gov (United States)

    Alling, A.; Allen, J.; Dempster, W.; Nelson, M.; Silverstone, S.; van Thillo, M.

    Results from the closure and initial closed ecological system research in the "Laboratory Biosphere" facility in Santa Fe, New Mexico (USA) will be presented. The facility was initially sealed in April 2002; and the first crop experiments with soybeans commenced in May 2002. The Laboratory Biosphere was created by the team which invented, built and operated Biosphere 2 during its years of closed ecological system functioning (1991-94) and is a testbed to build upon the lessons learned. It is an opportunity to continue experiments with a sustainable soil based agriculture system unlike most bioregenerative systems which use hydroponic systems dependent on a supply of nutrient solution. Because of the small volume of the system (34-45 m3), developing mechanisms to keep parameters like carbon dioxide within acceptable limits will be critical. Recycle of nutrients within the system to maintain soil fertility; and the ability of the inherent complex ecology of soils and a soil bed reactor to handle trace gas buildups are primary research goals. Other research goals are determination of short and long-term exchanges between soil, plants and atmosphere, especially for carbon dioxide, oxygen, nitrogen, NOX, and methane, impact of cultivation (tillage) on soil/atmospheric exchanges., investigation and development of strategies to return nutrients to the soil to maintain fertility, e.g. shredding biomass vs. composting, impact on soil chemistry of returning leachate water to the soil as irrigation water. The microbiological status of soils prior to experiments and over time will allow measurement of changes in microbial diversity and the determination of the role of soil microbes in biogeochemical cycles. Integration of automated sensor and control in the system with real-time modeling has importance for operation, research and educational outreach programs. The Laboratory Biosphere is intended to test and develop a "cybersphere" (network of shared intelligence) that may be

  19. Using the e-Chasqui, web-based information system, to determine laboratory guidelines and data available to clinical staff.

    Science.gov (United States)

    Blaya, Joaquin A; Yagui, Martin; Contreras, Carmen C; Palma, Betty; Shin, Sonya S; Yale, Gloria; Suarez, Carmen; Fraser, Hamish S F

    2008-11-06

    13% of all drug susceptibility tests (DSTs) performed at a public laboratory in Peru were duplicate. To determine reasons for duplicate requests an online survey was implemented in the e-Chasqui laboratory information system. Results showed that 59.6% of tests were ordered because clinical staff was unaware of ordering guidelines or of a previous result. This shows a benefit of using a web-based system and the lack of laboratory information available to clinical staff in Peru.

  20. HeMoLab--Hemodynamics Modelling Laboratory: an application for modelling the human cardiovascular system.

    Science.gov (United States)

    Larrabide, I; Blanco, P J; Urquiza, S A; Dari, E A; Vénere, M J; de Souza e Silva, N A; Feijóo, R A

    2012-10-01

    In this work we present HeMoLab (Hemodynamics Modeling Laboratory), a computational environment for modeling the Human Cardiovascular System. Its integrates novel computational tools, running from medical image processing to numerical simulation and visualization. As a simulation tool, it allows to accommodate complex physiological and/or pathophysiological (virtual) scenarios aimed to retrieve detailed information from the numerical computations. Such application makes possible to speed up research in the study and analysis of the cardiovascular system and, to provide a virtual laboratory for medical training and education, and specialized Human Resources development. In order to demonstrate the modeling and simulation capabilities of HeMoLab some cases of use are presented. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Idaho National Laboratory Integrated Safety Management System 2011 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Farren Hunt

    2011-12-01

    Idaho National Laboratory (INL) performed an annual Integrated Safety Management System (ISMS) effectiveness review per 48 Code of Federal Regulations (CFR) 970.5223-1, 'Integration of Environment, Safety and Health into Work Planning and Execution.' The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and helped identify target areas for focused improvements and assessments for fiscal year (FY) 2012. The information presented in this review of FY 2011 shows that the INL has performed many corrective actions and improvement activities, which are starting to show some of the desired results. These corrective actions and improvement activities will continue to help change culture that will lead to better implementation of defined programs, resulting in moving the Laboratory's performance from the categorization of 'Needs Improvement' to the desired results of 'Effective Performance.'

  2. Laboratory and field evaluation of a biological monitoring system using Corbicula fluminea and Mulinia lateralis

    Energy Technology Data Exchange (ETDEWEB)

    Waller, W.T.; Allen, H.J.; Schwalm, F.U.; Acevedo, M.F.; Ammann, L.P.; Dickson, K.L.; Kennedy, J.H. [Univ. of North Texas, Denton, TX (United States); Morgan, E.L. [Tennessee Technological Univ., Cookeville, TN (United States)

    1995-12-31

    Laboratory and field experiments have been performed to evaluate a non-invasive biomonitoring system using the Asiatic clam Corbicula fluminea and Mulinia lateralis. C. fluminea was exposed to simulated episodic toxicity events in the laboratory using copper, diazinon, and regulated flow rates. Group behavior during these simulated events was compared to behavior during unstressed periods to develop a statistical model and an alarm criteria. Bayou Chico, Pensacola Bay, FL, was the site for field experiments in which M. lateralis was placed in situ to evaluate the performance of the biomonitoring system. The biomonitoring system consists of proximity sensors which detect an aluminum foil target attached to the valve of an organism. Valve movements of the clams are then digitally recorded using a personal computer. Data collected from remote sites are telemetered to the lab using short wave radio. In its final form, the authors envision an in situ biological monitoring system using bivalves deployed in aquatic systems in conjunction with automated monitoring systems like those found at USGS gauging stations. A tool such as this could be used as a warning system to increase the probability of detecting toxic events as they occur.

  3. Lawrence Berkeley Laboratory, Berkeley, California solar energy system performance evaluation, July 1980-June 1981

    Energy Technology Data Exchange (ETDEWEB)

    Wetzel, P.E.

    1981-01-01

    The Lawrence Berkeley Laboratory site is an office building in California with an active solar energy system designed to supply from 23 to 33% of the space heating load and part of the hot water load. The solar heating system is equipped with 1428 square feet of flat-plate collectors, a 2000-gallon water storage tank, and two gas-fired boilers to supply auxiliary heat for both space heating and domestic hot water. Poor performance is reported, with the solar fraction being only 4%. Also given are the solar savings ratio, conventional fuel savings, system performance factor, and the coefficient of performance. The performance data are given for the collector, storage, solar water heating and solar space heating subsystems as well as the total system. Typical system operation and solar energy utilization are briefly described. The system design, performance evaluation techniques, weather data, and sensor technology are presented. (LEW)

  4. Laboratory tests in support of the MSRE reactive gas removal system

    Energy Technology Data Exchange (ETDEWEB)

    Rudolph, J.C.; Del Cul, G.D.; Caja, J.; Toth, L.M.; Williams, D.F.; Thomas, K.S.; Clark, D.E.

    1997-07-01

    The Molten Salt Reactor Experiment (MSRE) at Oak Ridge National Laboratory has been shut down since December 1969, at which time the molten salt mixture of LiF-BeF{sub 2}-ZrF{sub 4}-{sup 233}UF{sub 4} (64.5-30.3-5.0-0.13 mol%) was transferred to fuel salt drain tanks for storage. In the late 1980s, increased radiation in one of the gas lines from the drain tank was attributed to {sup 233}UF{sub 6}. In 1994 two gas samples were withdraw (from a gas line in the Vent House connecting to the drain tanks) and analyzed. Surprisingly, 350 mm Hg of F{sub 2}, 70 mm Hg of UF{sub 6}, and smaller amounts of other gases were found in both of the samples. To remote this gas from above the drain tanks and all of the associated piping, the reactive gas removal system (RGRS) was designed. This report details the laboratory testing of the RGRS, using natural uranium, prior to its implementation at the MSRE facility. The testing was performed to ensure that the equipment functioned properly and was sufficient to perform the task while minimizing exposure to personnel. In addition, the laboratory work provided the research and development effort necessary to maximize the performance of the system. Throughout this work technicians and staff who were to be involved in RGRS operation at the MSRE site worked directly with the research staff in completing the laboratory testing phase. Consequently, at the end of the laboratory work, the personnel who were to be involved in the actual operations had acquired all of the training and experience necessary to continue with the process of reactive gas removal.

  5. Results from laboratory tests of the two-dimensional Time-Encoded Imaging System.

    Energy Technology Data Exchange (ETDEWEB)

    Marleau, Peter; Brennan, James S.; Brubaker, Erik; Gerling, Mark D; Le Galloudec, Nathalie Joelle

    2014-09-01

    A series of laboratory experiments were undertaken to demonstrate the feasibility of two dimensional time-encoded imaging. A prototype two-dimensional time encoded imaging system was designed and constructed. Results from imaging measurements of single and multiple point sources as well as extended source distributions are presented. Time encoded imaging has proven to be a simple method for achieving high resolution two-dimensional imaging with potential to be used in future arms control and treaty verification applications.

  6. Data Driven Research at LIS: the Laboratory of Information Systems at UNICAMP

    OpenAIRE

    Medeiros, Claudia Bauzer; Santanchè, André; Madeira, Edmundo R. M.; Martins, Eliane; Magalhâes, Geovane C.; Baranauskas, Maria Cecilia C.; Leite, Neucimar J.; Torres, Ricardo da S.

    2011-01-01

    This article presents an overview of the research conducted at the Laboratory of Information Systems (LIS) at the Institute of Computing, UNICAMP. Its creation, in 1994, was motivated by the need to support data-driven research within multidisciplinary projects involving computer scientists and scientists from other fields. Throughout the years, it has housed projects in many domains - in agriculture, biodiversity, medicine, health, bioinformatics, urban planning, telecommunications, and spor...

  7. INRiM Time and Frequency Laboratory: A New Data Management System (DMS)

    Science.gov (United States)

    2010-11-01

    dei dati del Laboratorio di Tempo e Frequenza,” Manuale Operativo INRIM – 2000. [3] R. Costa, D. Orgiazzi, G. C. Cerretto, and V. Pettiti, 2010...flexibility of the system functions. In detail, the main DMS functions are: - automatic and manual execution, by means of an electronic Time...other laboratory equipments; - phase measurements (started manually ), performed by means of a multichannel phase-meter, among couples of frequency

  8. LiLa Booking System: Architecture and Conceptual Model of a Rig Booking System for On-Line Laboratories

    Directory of Open Access Journals (Sweden)

    Dr. Víctor A. Villagrá

    2011-11-01

    Full Text Available Many educational institutions acknowledged the importance of providing online-access to student laboratories. To optimize the use of the scarce and expensive resources such laboratories depend on, it is advisable to establish and setup a booking system that helps to administer access to them. This paper reports on the architecture and conceptual model of the rig booking system designed for the LiLa Portal, a web portal that makes virtual and remote experiments available on the Internet. The design of the booking system is based on a requirements analysis carried out by the EC funded LiLa project in cooperation with international partners from the Global Online Lab Consortium, GoLC.

  9. QUALITY MANAGEMENT SYSTEM IN CLINICAL LABORATORIES ACCORDING TO THE ISO 15189:2007 STANDARD - EVALUATION OF THE BENEFITS OF IMPLEMENTATION IN AN ASSISTED REPRODUCTION LABORATORY

    Directory of Open Access Journals (Sweden)

    A.D. Sialakouma

    2011-03-01

    Full Text Available Biomedical science is a sensitive discipline and presents unique challenges due to its social character, continuous development and competitiveness. The issue of quality management systems and accreditation is gaining increasing interest in this sector. All over Europe, Health Services Units have started to introduce quality management systems and harmonization of criteria for accreditation is of increasing importance. Moreover, clinical laboratories, like the Assisted Reproduction laboratories and biochemical laboratories are required to apply a Quality Management System in order to ensure their correct, scientific and effective operation. Ultimately, it is a moral obligation for every health care organisation to supply the best possible care for the patient. The specific features and the diversity of clinical laboratories led to the introduction (2003 and, recently to the revision (2007 of the international standard ISO 15189, which is the first international standard developed specifically to address the requirements for accreditation of this type of laboratory. The basic principles for the quality assurance in the clinical laboratories are: x Complete and unambiguous standardized operating procedures. x Complete and unambiguous directives of operation. x Obligatory detailed written documentation, i.e., how each action is done, who will do it, where will this action take place and when. x Suitable scheduling of calibration/control/preventive maintenance of laboratory equipment and recording of each activity. x Distribution of responsibilities among the staff and continuous education and briefing according to current scientific data. x Complete and informed record file keeping. x Continuous improvement which is monitored with the adoption of quantified indicators. x Internal and external audit of all activities. x Troubleshooting. All these principles should be supported by the Management in order that the necessary adaptations should be made

  10. Applying IEEE storage system management standards at the National Storage Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Louis, S.; Hyer, S.W.

    1992-12-04

    Since its inception in 1990, the IEEE Storage System Standards Working Group has identified storage-system management as an area in need of further development The pressing need for standards in storage-system management arises from the requirement to exchange management information and to provide control in a consistent predictable manner between the components of a storage system. An appropriate set of management standards will allow multiple vendors to supply storage management subsystems or applications that are integral to or compatible with new storage systems conforming to future IEEE standards. An early, practical application of IEEE storage-system-management work is being pursued at the National Storage Laboratory (NSL), a recently-formed industrial collaboration at Lawrence Livermore National Laboratory. The NSL`s purpose is to develop advanced hardware and software technologies for high-performance, distributed storage systems. Since storage system management is of critical concern, it is being explored in depth at the NSL. Work was initiated to define basic management requirements and develop generalized graphical-user-interface tools using remote-procedure-call mechanisms to implement the NSL`s conceptual management framework. Several constraints were imposed on the development of early versions of this work to maintain compatibility with the NSL`s underlying UniTree-based software architecture and to provide timely prototypes and proof of concept. The project leverages the on-going standards work of the IEEE Storage System Standards Working Group (SSSWG) and also explores some of the relationships and interactions between IEEE storage-system management and more well known management methods for distributed systems and networks. It will have long term benefits by providing ``real-life`` storage-system-management requirements to the IEEE SSSWG for validation of evolving standards.

  11. An exploratory investigation of the translation of Pacific Northwest Laboratory`s print manuals system to an on-line manuals system

    Energy Technology Data Exchange (ETDEWEB)

    Heubach, J.G.; Hunt, S.T.; Pond, L.R.

    1992-06-01

    Information management technology has proliferated in the past decade in response to the information explosion. As documentation accumulates, the need to access information residing in manuals, handbooks and regulations conveniently, accurately, and quickly has increased. However, studies show that only fractions of the available information is read (Martin, 1978). Consequently, one of the biggest challenges in linking information and electronic management of information is to use the power of communication technology to meet the information needs of the audience. Pacific Northwest Laboratories` (PNL) investigation of translating its print manual system to an on-line system fits this challenge precisely. PNL`s manuals contain a tremendous amount of information for which manual holders are responsible. To perform their tasks in compliance with policy and procedure guidelines, users need to access information accurately, conveniently, and quickly. In order to select and use information management tools wisely, answers must be sought to a few basic questions. Communication experts cite four key questions: What do users want? What do users need? What characteristics of an on-line information system affect its usefulness? Who are the users whose wants and needs are to be met? Once these questions are answered, attention can be focused on finding the best match between user requirements and technology characteristics and weighing the costs and benefits of proposed options.

  12. Integrating Environmental Management in Chemical Engineering Education by Introducing an Environmental Management System in the Student's Laboratory

    Science.gov (United States)

    Montanes, Maria T.; Palomares, Antonio E.

    2008-01-01

    In this work we show how specific challenges related to sustainable development can be integrated into chemical engineering education by introducing an environmental management system in the laboratory where the students perform their experimental lessons. It is shown how the system has been developed and implemented in the laboratory, what role…

  13. Pharmacokinetics of methylphenidate transdermal system (MTS): results from a laboratory classroom study.

    Science.gov (United States)

    Pierce, David; Dixon, Catherine M; Wigal, Sharon B; McGough, James J

    2008-08-01

    To evaluate the pharmacokinetic properties of the methylphenidate transdermal system (MTS) in pediatric patients diagnosed with ADHD (attention-deficit/hyperactivity disorder) in a laboratory school setting. A phase II, randomized, double-blind, placebo-controlled, laboratory classroom study was conducted with prior dose optimization. Children (aged 6-12 years) with ADHD were titrated over 5 weeks to an optimal clinical MTS dose (10, 15, 20, or 30 mg/9 h). Participants were randomized to 1 week of either MTS or corresponding placebo, followed by crossover to the alternate treatment. Laboratory school evaluations, including pharmacokinetic blood sampling, occurred at the end of each treatment. MTS delivered d- and l-MPH (methylphenidate) into the systemic circulation throughout the 9-hour wear time, and plasma concentrations declined rapidly after patch removal. Over the time-course of clinical effectiveness (2-12 h), mean plasma concentrations of d-MPH at the most frequently titrated doses (15 and 20 mg/9 h) ranged from 4.97 to 28.3 ng/mL. Systemic exposure increased approximately dose proportionately. Plasma concentrations of the l-MPH were approximately one-half to two-thirds those for d-MPH. Plasma concentrations of the much less active l-MPH were consistently lower than those of d-MPH. The clinical relevance of the MTS pharmacokinetic profile is discussed.

  14. Role of WhatsApp Messenger in the Laboratory Management System: A Boon to Communication.

    Science.gov (United States)

    Dorwal, Pranav; Sachdev, Ritesh; Gautam, Dheeraj; Jain, Dharmendra; Sharma, Pooja; Tiwari, Assem Kumar; Raina, Vimarsh

    2016-01-01

    The revolution of internet and specifically mobile internet has occurred at a blinding pace over the last decade. With the advent of smart phones, the hand held device has become much more than a medium of voice calling. Healthcare has been catching up with the digital revolution in the form of Hospital Information System and Laboratory Information System. However, the advent of instant messaging services, which are abundantly used by the youth, can be used to improve communication and coordination among the various stake holders in the healthcare sector. We have tried to look at the impact of using the WhatsApp messenger service in the laboratory management system, by forming multiple groups of the various subsections of the laboratory. A total of 35 members used this service for a period of 3 months and their response was taken on a scale of 1 to 10. There was significant improvement in the communication in the form of sharing photographic evidence, information about accidents, critical alerts, duty rosters, academic activities and getting directives from seniors. There was also some increase in the load of adding information to the application and disturbance in the routine activities; but the benefits far outweighed the minor hassles. We thereby suggest and foresee another communication revolution which will change the way information is shared in a healthcare sector, with hospital specific dedicated apps.

  15. A manual for a Laboratory Information Management System (LIMS) for light stable isotopes

    Science.gov (United States)

    Coplen, Tyler B.

    1998-01-01

    The reliability and accuracy of isotopic data can be improved by utilizing database software to (i) store information about samples, (ii) store the results of mass spectrometric isotope-ratio analyses of samples, (iii) calculate analytical results using standardized algorithms stored in a database, (iv) normalize stable isotopic data to international scales using isotopic reference materials, and (v) generate multi-sheet paper templates for convenient sample loading of automated mass-spectrometer sample preparation manifolds. Such a database program is presented herein. Major benefits of this system include (i) an increase in laboratory efficiency, (ii) reduction in the use of paper, (iii) reduction in workload due to the elimination or reduction of retyping of data by laboratory personnel, and (iv) decreased errors in data reported to sample submitters. Such a database provides a complete record of when and how often laboratory reference materials have been analyzed and provides a record of what correction factors have been used through time. It provides an audit trail for stable isotope laboratories. Since the original publication of the manual for LIMS for Light Stable Isotopes, the isotopes 3 H, 3 He, and 14 C, and the chlorofluorocarbons (CFCs), CFC-11, CFC-12, and CFC-113, have been added to this program.

  16. Air-conditioned university laboratories: Comparing CO2 measurement for centralized and split-unit systems

    Directory of Open Access Journals (Sweden)

    M. Hussin

    2017-04-01

    Full Text Available Universities are designed for higher education learning, and improving university indoor air quality (IAQ is essential to the enhanced performances of students and staff members alike. The majority of IAQ problems are due to inadequate ventilation in university buildings. Carbon Dioxide (CO2 measurements have become a commonly used screening test of IAQ because measurement levels can be used to evaluate the amount of ventilation and general comfort. This paper examines CO2 field measurement for undergraduate practical classes. Ten air conditioned laboratories with ventilation were chosen for CO2 field measurement. CO2 was monitored under indoor and outdoor conditions. Indoor CO2 concentration for Laboratories 1 and 10 is observed to be higher than 1000 ppm which indicated inadequate ventilation, while other laboratories showed CO2 concentrations less than 1000 ppm. Air capacity and outdoor air were calculated based on the design documentation. A comparison between design and actual outdoor air/person values indicates that the air conditioning systems of the laboratories had adequate ventilation.

  17. Establishment of an Environmental Control Technology Laboratory with a Circulating Fluidized-Bed Combustion System

    Energy Technology Data Exchange (ETDEWEB)

    Wei-Ping Pan; Yan Cao; John Smith

    2008-05-31

    On February 14, 2002, President Bush announced the Clear Skies Initiative, a legislative proposal to control the emissions of nitrogen oxides (NO{sub x}), sulfur dioxide (SO{sub 2}), and mercury from power plants. In response to this initiative, the National Energy Technology Laboratory organized a Combustion Technology University Alliance and hosted a Solid Fuel Combustion Technology Alliance Workshop. The workshop identified multi-pollutant control; improved sorbents and catalysts; mercury monitoring and capture; and improved understanding of the underlying reaction chemistry occurring during combustion as the most pressing research needs related to controlling environmental emissions from fossil-fueled power plants. The Environmental Control Technology Laboratory will help meet these challenges and offer solutions for problems associated with emissions from fossil-fueled power plants. The goal of this project was to develop the capability and technology database needed to support municipal, regional, and national electric power generating facilities to improve the efficiency of operation and solve operational and environmental problems. In order to effectively provide the scientific data and the methodologies required to address these issues, the project included the following aspects: (1) Establishing an Environmental Control Technology Laboratory using a laboratory-scale, simulated fluidized-bed combustion (FBC) system; (2) Designing, constructing, and operating a bench-scale (0.6 MW{sub th}), circulating fluidized-bed combustion (CFBC) system as the main component of the Environmental Control Technology Laboratory; (3) Developing a combustion technology for co-firing municipal solid waste (MSW), agricultural waste, and refuse-derived fuel (RDF) with high sulfur coals; (4) Developing a control strategy for gaseous emissions, including NO{sub x}, SO{sub 2}, organic compounds, and heavy metals; and (5) Developing new mercury capturing sorbents and new

  18. Real-Time Hardware-in-the-Loop Laboratory Testing for Multisensor Sense and Avoid Systems

    Directory of Open Access Journals (Sweden)

    Giancarmine Fasano

    2013-01-01

    Full Text Available This paper focuses on a hardware-in-the-loop facility aimed at real-time testing of architectures and algorithms of multisensor sense and avoid systems. It was developed within a research project aimed at flight demonstration of autonomous non-cooperative collision avoidance for Unmanned Aircraft Systems. In this framework, an optionally piloted Very Light Aircraft was used as experimental platform. The flight system is based on multiple-sensor data integration and it includes a Ka-band radar, four electro-optical sensors, and two dedicated processing units. The laboratory test system was developed with the primary aim of prototype validation before multi-sensor tracking and collision avoidance flight tests. System concept, hardware/software components, and operating modes are described in the paper. The facility has been built with a modular approach including both flight hardware and simulated systems and can work on the basis of experimentally tested or synthetically generated scenarios. Indeed, hybrid operating modes are also foreseen which enable performance assessment also in the case of alternative sensing architectures and flight scenarios that are hardly reproducible during flight tests. Real-time multisensor tracking results based on flight data are reported, which demonstrate reliability of the laboratory simulation while also showing the effectiveness of radar/electro-optical fusion in a non-cooperative collision avoidance architecture.

  19. Idaho National Laboratory Integrated Safety Management System 2010 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Thomas J. Haney

    2010-12-01

    Idaho National Laboratory completes an annual Integrated Safety Management System effectiveness review per 48 CFR 970.5223-1 “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assesses ISMS effectiveness, provides feedback to maintain system integrity, and helps identify target areas for focused improvements and assessments for the following year. Using one of the three Department of Energy (DOE) descriptors in DOE M 450.4-1 regarding the state of ISMS effectiveness during Fiscal Year (FY) 2010, the information presented in this review shows that INL achieved “Effective Performance.”

  20. A new and compact system at the AMS laboratory in Bucharest

    Energy Technology Data Exchange (ETDEWEB)

    Stan-Sion, C.; Enachescu, M.; Petre, A.R.; Simion, C.A.; Calinescu, C.I.; Ghita, D.G.

    2015-10-15

    AMS research started more than 15 years ago at our National Institute for Physics and Nuclear Engineering (IFIN-HH), Bucharest. A first facility was constructed based on our multipurpose 9 MV tandem accelerator and was upgraded several times. In May 2012 a new Cockcroft Walton type 1 MV HVEE tandetron AMS system, was commissioned. Two chemistry laboratories were constructed and are routinely performing the target preparation for carbon dating and for other isotope applications such as for geology, environment physics, medicine and forensic physics. Performance parameters of the new system are shown.

  1. A tide prediction and tide height control system for laboratory mesocosms.

    Science.gov (United States)

    Miller, Luke P; Long, Jeremy D

    2015-01-01

    Experimental mesocosm studies of rocky shore and estuarine intertidal systems may benefit from the application of natural tide cycles to better replicate variation in immersion time, water depth, and attendant fluctuations in abiotic and edaphic conditions. Here we describe a stand-alone microcontroller tide prediction open-source software program, coupled with a mechanical tidal elevation control system, which allows continuous adjustment of aquarium water depths in synchrony with local tide cycles. We used this system to monitor the growth of Spartina foliosa marsh cordgrass and scale insect herbivores at three simulated shore elevations in laboratory mesocosms. Plant growth decreased with increasing shore elevation, while scale insect population growth on the plants was not strongly affected by immersion time. This system shows promise for a range of laboratory mesocosm studies where natural tide cycling could impact organism performance or behavior, while the tide prediction system could additionally be utilized in field experiments where treatments need to be applied at certain stages of the tide cycle.

  2. Remote Systems Experience at the Oak Ridge National Laboratory--A Summary of Lessons Learned

    Energy Technology Data Exchange (ETDEWEB)

    Noakes, Mark W [ORNL; Burgess, Thomas W [ORNL; Rowe, John C [ORNL

    2011-01-01

    Oak Ridge National Laboratory (ORNL) has a long history in the development of remote systems to support the nuclear environment. ORNL, working in conjunction with Central Research Laboratories, created what is believed to be the first microcomputer-based implementation of dual-arm master-slave remote manipulation. As part of the Consolidated Fuel Reprocessing Program, ORNL developed the dual-arm advanced servomanipulator focusing on remote maintainability for systems exposed to high radiation fields. ORNL also participated in almost all of the various technical areas of the U.S. Department of Energy s Robotics Technology Development Program, while leading the Decontamination and Decommissioning and Tank Waste Retrieval categories. Over the course of this involvement, ORNL has developed a substantial base of working knowledge as to what works when and under what circumstances for many types of remote systems tasks as well as operator interface modes, control bandwidth, and sensing requirements to name a few. By using a select list of manipulator systems that is not meant to be exhaustive, this paper will discuss history and outcome of development, field-testing, deployment, and operations from a lessons learned perspective. The final outcome is a summary paper outlining ORNL experiences and guidelines for transition of developmental remote systems to real-world hazardous environments.

  3. Near Field UHF RFID Antenna System Enabling the Tracking of Small Laboratory Animals

    Directory of Open Access Journals (Sweden)

    Luca Catarinucci

    2013-01-01

    Full Text Available Radio frequency identification (RFID technology is more and more adopted in a wide range of applicative scenarios. In many cases, such as the tracking of small-size living animals for behaviour analysis purposes, the straightforward use of commercial solutions does not ensure adequate performance. Consequently, both RFID hardware and the control software should be tailored for the particular application. In this work, a novel RFID-based approach enabling an effective localization and tracking of small-sized laboratory animals is proposed. It is mainly based on a UHF Near Field RFID multiantenna system, to be placed under the animals’ cage, and able to rigorously identify the NF RFID tags implanted in laboratory animals (e.g., mice. Once the requirements of the reader antenna have been individuated, the antenna system has been designed and realized. Moreover, an algorithm based on the measured Received Signal Strength Indication (RSSI aiming at removing potential ambiguities in data captured by the multiantenna system has been developed and integrated. The animal tracking system has been largely tested on phantom mice in order to verify its ability to precisely localize each subject and to reconstruct its path. The achieved and discussed results demonstrate the effectiveness of the proposed tracking system.

  4. A tide prediction and tide height control system for laboratory mesocosms

    Directory of Open Access Journals (Sweden)

    Luke P. Miller

    2015-11-01

    Full Text Available Experimental mesocosm studies of rocky shore and estuarine intertidal systems may benefit from the application of natural tide cycles to better replicate variation in immersion time, water depth, and attendant fluctuations in abiotic and edaphic conditions. Here we describe a stand-alone microcontroller tide prediction open-source software program, coupled with a mechanical tidal elevation control system, which allows continuous adjustment of aquarium water depths in synchrony with local tide cycles. We used this system to monitor the growth of Spartina foliosa marsh cordgrass and scale insect herbivores at three simulated shore elevations in laboratory mesocosms. Plant growth decreased with increasing shore elevation, while scale insect population growth on the plants was not strongly affected by immersion time. This system shows promise for a range of laboratory mesocosm studies where natural tide cycling could impact organism performance or behavior, while the tide prediction system could additionally be utilized in field experiments where treatments need to be applied at certain stages of the tide cycle.

  5. Importance of Public-Private Partnerships: Strengthening Laboratory Medicine Systems and Clinical Practice in Africa.

    Science.gov (United States)

    Shrivastava, Ritu; Gadde, Renuka; Nkengasong, John N

    2016-04-15

    After the launch of the US President's Emergency Plan for AIDS Relief in 2003, it became evident that inadequate laboratory systems and services would severely limit the scale-up of human immunodeficiency virus infection prevention, care, and treatment programs. Thus, the Office of the US Global AIDS Coordinator, Centers for Disease Control and Prevention, and Becton, Dickinson and Company developed a public-private partnership (PPP). Between October 2007 and July 2012, the PPP combined the competencies of the public and private sectors to boost sustainable laboratory systems and develop workforce skills in 4 African countries. Key accomplishments of the initiative include measurable and scalable outcomes to strengthen national capacities to build technical skills, develop sample referral networks, map disease prevalence, support evidence-based health programming, and drive continuous quality improvement in laboratories. This report details lessons learned from our experience and a series of recommendations on how to achieve successful PPPs. © The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.

  6. Physiolab: A new laboratory for the study of the cardio-vascular system

    Science.gov (United States)

    Marsal, O.; André-Deshays, C.; Cauquil, D.; Kotovskaya, A.; Gratchev, V.; Noskin, A.

    On the basis of the experience gained during the previous french-russian missions on board MIR about the adaptation processes of the cardio-vascular system, a new laboratory has been designed. The objective of this "PHYSIOLAB" is to have a better understanding of the mechanisms underlying the changes in the cardio-vascular system, with a special emphasis on the phenomenon of cardio-vascular deconditioning after landing. Beyond these scientific objectives, it is also intended to use PHYSIOLAB to help in the medical monitoring on-board MIR, during functional tests such as LBNP. PHYSIOLAB will be set up in MIR by the French cosmonaut during the next french-russian CASSIOPEE mission in 1996. Its architecture is based on a central unit, which controls the experimental protocols, records the results and provides an interface for transmission to the ground via telemetry. Different specific modules are used for the acquisition of various physiological parameters. This PHYSIOLAB under development for the CASSIOPEE mission should evolve towards a more ambitious laboratory, whose definition would take into account the results obtained with the first version of PHYSIOLAB. This "second generation" laboratory should be developed in the frame of wide international cooperation.

  7. Laboratory testing of the in-well vapor-stripping system

    Energy Technology Data Exchange (ETDEWEB)

    Gilmore, T.J.; Francois, O.

    1996-03-01

    The Volatile organic Compounds-Arid Integrated Demonstration (VOC-Arid ID) was implemented by the US Department of Energy`s (DOE`s) Office of Technology Development to develop and test new technologies for the remediation of organic chemicals in the subsurface. One of the technologies being tested under the VOC-Arid ID is the in-well vapor-stripping system. The in-well vapor-stripping concept was initially proposed by researchers at Stanford University and is currently under development through a collaboration between workers at Stanford University and DOE`s Pacific Northwest National Laboratory. The project to demonstrate the in-well vapor-stripping technology is divided into three phases: (1) conceptual model and computer simulation, (2) laboratory testing, and (3) field demonstration. This report provides the methods and results of the laboratory testing in which a full-scale replica was constructed and tested above ground in a test facility located at DOE`s Hanford Site, Washington. The system is a remediation technology designed to preferentially extract volatile organic compounds (VOCs) from contaminated groundwater by converting them to a vapor phase.

  8. Intercomparison of in vivo monitoring systems in Europe. Results from Risoe National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Lauridsen, B.; Soegaard-Hansen, J.

    1996-12-01

    This report contains the contribution from Risoe National Laboratory to the European project: `Intercomparison of in Vivo Monitoring Systems in Europe`. The whole-body counter at Risoe and the measurement on a phantom used as an intercalibration object in the project is described. In four case studies, prepared by the project coordinator, intakes of radionuclides and resulting doses are calculated. These calculations are based on informations on the radioactive materials taken into the body, routes of intake and on body contents of radionuclides from simulated single or multiple whole-body measurement. The answer from Risoe National Laboratory to two questionnaires - one on the whole-body counting facility and calibration methods and one on the legal requirements is the country - is listed. (au).

  9. Experience in implementing a quality management system in a tuberculosis laboratory, Kisumu, Kenya.

    Science.gov (United States)

    Musau, S; McCarthy, K; Okumu, A; Shinnick, T; Wandiga, S; Williamson, J; Cain, K

    2015-06-01

    We implemented a quality management system (QMS) and documented our improvements in a tuberculosis (TB) laboratory in Kisumu, Kenya. After implementation of the QMS, a sustained reduction in culture contamination rates for solid (from 15.4% to 5.3%) and liquid media (from 15.2% to 9.3%) was observed, and waste from product expiry was reduced significantly. External quality assurance (EQA) results were satisfactory before and after QMS implementation, and a client survey after implementation revealed 98% satisfaction. The laboratory attained ISO 15189 accreditation in October 2013. The implementation of QMS facilitated the attainment of target quality indicators, reduced waste due to expiry and led to high client satisfaction.

  10. IT Tools for Foresight: The Integrated Insight and Response System of Deutsche Telekom Innovation Laboratories

    DEFF Research Database (Denmark)

    Rohrbeck, René; Thom, Nico; Arnold, Heinrich

    2015-01-01

    In this article we present and discuss the IT tools that Deutsche Telekom Innovation Laboratories use to support their corporate foresight activities. These tools are integrated into an approach that encompasses the discovery of change, interpretation, and triggering managerial responses. The ove......In this article we present and discuss the IT tools that Deutsche Telekom Innovation Laboratories use to support their corporate foresight activities. These tools are integrated into an approach that encompasses the discovery of change, interpretation, and triggering managerial responses....... The overall system consists of a tool for scanning for weak signals on change (PEACOQ Scouting Tool), a tool for collecting internal ideas (PEACOQ Gate 0.5), and a tool for triggering organizational responses (Foresight Landing page). Particularly the link to innovation management and R&D strategy...

  11. A virtual laboratory for three-phase flow dynamics in the magmatic system

    Science.gov (United States)

    Qin, Z.; Suckale, J.; Culha, C.

    2016-12-01

    The multiphase interactions between gas bubbles, crystals and magmatic liquid are key for understanding magmatic convection, but are notoriously difficult to capture in numerical models. Unlike early models that assume perfectly homogeneous mixtures, gas emission from natural systems suggests that the gas phase always separates from the flow and drives eruptive activity. Also, observational data revealed the existence of crystal layers and rheological instabilities that may result from preferential crystal alignment and phase separation in gas-bearing crystalline mushes. In this paper, we build a virtual laboratory for the multiphase interaction in magmatic systems with an emphasis on low to intermediate crystallinities. In this virtual laboratory, we combine a topology-preserving advection scheme for tracking the gas bubbles with a Distributed-Lagrange-Multipliers approach coupled to an Immersed-Boundary method to capture the motion of solid particles. The combined strategy allows us to simulate crystal and bubble interactions as well as capture bursting of bubbles on the free surface. To achieve higher resolution and avoid short time step associated with the high viscosity contrast between the magma and the gas, we couple an adaptive projection to a time-splitting strategy in conjunction with the approximate-factorization technique to efficiently solve the governing equations consisting of the continuity, momentum and energy components. We have carefully benchmarked our numerical approach against analytical results and laboratory experiments. To validate our virtual laboratory in a natural setting, we simulate the lava lake at Mount Erebus, a large intraplate stratovolcano at Ross Island, Antarctica. Various observations of thermal flux, seismic behavior, geodesy and geochemistry is synthesized to deduce constraints on the mass flux, conduit dimensions, reservoir size, and crystal growth as a basis for our numerical experiments. The significant agreement between

  12. A programmable closed-loop recording and stimulating wireless system for behaving small laboratory animals

    Science.gov (United States)

    Angotzi, Gian Nicola; Boi, Fabio; Zordan, Stefano; Bonfanti, Andrea; Vato, Alessandro

    2014-08-01

    A portable 16-channels microcontroller-based wireless system for a bi-directional interaction with the central nervous system is presented in this work. The device is designed to be used with freely behaving small laboratory animals and allows recording of spontaneous and evoked neural activity wirelessly transmitted and stored on a personal computer. Biphasic current stimuli with programmable duration, frequency and amplitude may be triggered in real-time on the basis of the recorded neural activity as well as by the animal behavior within a specifically designed experimental setup. An intuitive graphical user interface was developed to configure and to monitor the whole system. The system was successfully tested through bench tests and in vivo measurements on behaving rats chronically implanted with multi-channels microwire arrays.

  13. Combustion Research Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Combustion Research Laboratory facilitates the development of new combustion systems or improves the operation of existing systems to meet the Army's mission for...

  14. Full impact of laboratory information system requires direct use by clinical staff: cluster randomized controlled trial.

    Science.gov (United States)

    Blaya, Joaquín A; Shin, Sonya; Contreras, Carmen; Yale, Gloria; Suarez, Carmen; Asencios, Luis; Kim, Jihoon; Rodriguez, Pablo; Cegielski, Peter; Fraser, Hamish S F

    2011-01-01

    To evaluate the time to communicate laboratory results to health centers (HCs) between the e-Chasqui web-based information system and the pre-existing paper-based system. Cluster randomized controlled trial in 78 HCs in Peru. In the intervention group, 12 HCs had web access to results via e-Chasqui (point-of-care HCs) and forwarded results to 17 peripheral HCs. In the control group, 22 point-of-care HCs received paper results directly and forwarded them to 27 peripheral HCs. Baseline data were collected for 15 months. Post-randomization data were collected for at least 2 years. Comparisons were made between intervention and control groups, stratified by point-of-care versus peripheral HCs. For point-of-care HCs, the intervention group took less time to receive drug susceptibility tests (DSTs) (median 9 vs 16 days, p60 days to arrive (pChasqui information system had reduced communication times and fewer results with delays of >2 months. Peripheral HCs had no benefits from the system. This suggests that health establishments should have point-of-care access to reap the benefits of electronic laboratory reporting.

  15. Photovoltaic Device Performance Evaluation Using an Open-Hardware System and Standard Calibrated Laboratory Instruments

    Directory of Open Access Journals (Sweden)

    Jesús Montes-Romero

    2017-11-01

    Full Text Available This article describes a complete characterization system for photovoltaic devices designed to acquire the current-voltage curve and to process the obtained data. The proposed system can be replicated for educational or research purposes without having wide knowledge about electronic engineering. Using standard calibrated instrumentation, commonly available in any laboratory, the accuracy of measurements is ensured. A capacitive load is used to bias the device due to its versatility and simplicity. The system includes a common part and an interchangeable part that must be designed depending on the electrical characteristics of each PV device. Control software, developed in LabVIEW, controls the equipment, performs automatic campaigns of measurements, and performs additional calculations in real time. These include different procedures to extrapolate the measurements to standard test conditions and methods to obtain the intrinsic parameters of the single diode model. A deep analysis of the uncertainty of measurement is also provided. Finally, the proposed system is validated by comparing the results obtained from some commercial photovoltaic modules to the measurements given by an independently accredited laboratory.

  16. 75 FR 50987 - Privacy Act System of Records; National Animal Health Laboratory Network (NAHLN)

    Science.gov (United States)

    2010-08-18

    ... Coordinator, National Veterinary Services Laboratories, Veterinary Services, APHIS, 1800 Dayton Avenue, Ames..., position, telephone number, and e-mail address; emergency contact information; and proficiency test results... laboratory submissions, purpose and reason for laboratory submissions, test methods, test equipment, test...

  17. Assessment of patient safety culture in clinical laboratories in the Spanish National Health System.

    Science.gov (United States)

    Giménez-Marín, Angeles; Rivas-Ruiz, Francisco; García-Raja, Ana M; Venta-Obaya, Rafael; Fusté-Ventosa, Margarita; Caballé-Martín, Inmaculada; Benítez-Estevez, Alfonso; Quinteiro-García, Ana I; Bedini, José Luis; León-Justel, Antonio; Torra-Puig, Montserrat

    2015-01-01

    There is increasing awareness of the importance of transforming organisational culture in order to raise safety standards. This paper describes the results obtained from an evaluation of patient safety culture in a sample of clinical laboratories in public hospitals in the Spanish National Health System. A descriptive cross-sectional study was conducted among health workers employed in the clinical laboratories of 27 public hospitals in 2012. The participants were recruited by the heads of service at each of the participating centers. Stratified analyses were performed to assess the mean score, standardized to a base of 100, of the six survey factors, together with the overall patient safety score. 740 completed questionnaires were received (88% of the 840 issued). The highest standardized scores were obtained in Area 1 (individual, social and cultural) with a mean value of 77 (95%CI: 76-78), and the lowest ones, in Area 3 (equipment and resources), with a mean value of 58 (95%CI: 57-59). In all areas, a greater perception of patient safety was reported by the heads of service than by other staff. We present the first multicentre study to evaluate the culture of clinical safety in public hospital laboratories in Spain. The results obtained evidence a culture in which high regard is paid to safety, probably due to the pattern of continuous quality improvement. Nevertheless, much remains to be done, as reflected by the weaknesses detected, which identify areas and strategies for improvement.

  18. The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory.

    Science.gov (United States)

    Morris, Chris; Pajon, Anne; Griffiths, Susanne L; Daniel, Ed; Savitsky, Marc; Lin, Bill; Diprose, Jonathan M; da Silva, Alan Wilter; Pilicheva, Katya; Troshin, Peter; van Niekerk, Johannes; Isaacs, Neil; Naismith, James; Nave, Colin; Blake, Richard; Wilson, Keith S; Stuart, David I; Henrick, Kim; Esnouf, Robert M

    2011-04-01

    The techniques used in protein production and structural biology have been developing rapidly, but techniques for recording the laboratory information produced have not kept pace. One approach is the development of laboratory information-management systems (LIMS), which typically use a relational database schema to model and store results from a laboratory workflow. The underlying philosophy and implementation of the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales, is described. PiMS is a web-based Java application that uses either Postgres or Oracle as the underlying relational database-management system. PiMS is available under a free licence to all academic laboratories either for local installation or for use as a managed service.

  19. Implementation and user satisfaction with forensic laboratory information systems in death investigation offices.

    Science.gov (United States)

    Levy, Bruce P

    2013-03-01

    The use of laboratory information management systems (LIMSs) in forensic pathology and death investigation systems has lagged behind the greater pathology community. Yet the logistical needs of a modern medical examiner or coroner office could be well served by a robust forensic LIMS, and the data stored in a forensic LIMS could be effectively mined for the protection of the public's health and safety.In spring 2007, the National Association of Medical Examiners conducted a survey of its members to determine the use of and satisfaction with forensic LIMS. This survey was repeated in the fall of 2011. The responses to the 2 surveys were compared to note any trends or changes to LIMS use by medical examiners and coroners.Although the use of LIMS has increased in the 4 1/2 years between surveys, 18% of death investigation systems still do not have a forensic LIMS. The percentage of offices with home-developed systems has increased, whereas the user's satisfaction with these systems has decreased. This may be due to limited budgets to either purchase or develop systems. The integration of images into these systems has increased, but not nearly to the level that should be present in an image-dependent field. Users of these systems are cognizant of the features that a forensic LIMS should have to ensure the smooth operation of a death investigation office.

  20. Machine Translation Projects for Portuguese at INESC ID's Spoken Language Systems Laboratory

    Directory of Open Access Journals (Sweden)

    Anabela Barreiro

    2014-12-01

    Full Text Available Language technologies, in particular machine translation applications, have the potential to help break down linguistic and cultural barriers, presenting an important contribution to the globalization and internationalization of the Portuguese language, by allowing content to be shared 'from' and 'to' this language. This article aims to present the research work developed at the Laboratory of Spoken Language Systems of INESC-ID in the field of machine translation, namely the automated speech translation, the translation of microblogs and the creation of a hybrid machine translation system. We will focus on the creation of the hybrid system, which aims at combining linguistic knowledge, in particular semantico-syntactic knowledge, with statistical knowledge, to increase the level of translation quality.

  1. Critical analysis of laboratory measurements and monitoring system of water-pipe network corrosion-case study.

    Directory of Open Access Journals (Sweden)

    Agata Jazdzewska

    2016-06-01

    Full Text Available Case study of corrosion failure of urban water supply system caused by environmental factors was presented. Nowadays corrosion monitoring of water distribution systems is an object of major concern. There is possibility of application broad range of techniques like gravimetric and electrochemical. Both kinds of techniques can be applied in laboratory and field conditions. In many cases researches limit the case analysis to measurements in laboratory conditions. Presented work contain critical analysis of results obtained in laboratory and field conditions based on corrosion monitoring of three pipelines systems failure in Krakow.

  2. Laboratory model of the cardiovascular system for experimental demonstration of pulse wave propagation

    Science.gov (United States)

    Stojadinović, Bojana; Nestorović, Zorica; Djurić, Biljana; Tenne, Tamar; Zikich, Dragoslav; Žikić, Dejan

    2017-03-01

    The velocity by which a disturbance moves through the medium is the wave velocity. Pulse wave velocity is among the key parameters in hemodynamics. Investigation of wave propagation through the fluid-filled elastic tube has a great importance for the proper biophysical understanding of the nature of blood flow through the cardiovascular system. Here, we present a laboratory model of the cardiovascular system. We have designed an experimental setup which can help medical and nursing students to properly learn and understand basic fluid hemodynamic principles, pulse wave and the phenomenon of wave propagation in blood vessels. Demonstration of wave propagation allowed a real time observation of the formation of compression and expansion waves by students, thus enabling them to better understand the difference between the two waves, and also to measure the pulse wave velocity for different fluid viscosities. The laboratory model of the cardiovascular system could be useful as an active learning methodology and a complementary tool for understanding basic principles of hemodynamics.

  3. MendeLIMS: a web-based laboratory information management system for clinical genome sequencing.

    Science.gov (United States)

    Grimes, Susan M; Ji, Hanlee P

    2014-08-27

    Large clinical genomics studies using next generation DNA sequencing require the ability to select and track samples from a large population of patients through many experimental steps. With the number of clinical genome sequencing studies increasing, it is critical to maintain adequate laboratory information management systems to manage the thousands of patient samples that are subject to this type of genetic analysis. To meet the needs of clinical population studies using genome sequencing, we developed a web-based laboratory information management system (LIMS) with a flexible configuration that is adaptable to continuously evolving experimental protocols of next generation DNA sequencing technologies. Our system is referred to as MendeLIMS, is easily implemented with open source tools and is also highly configurable and extensible. MendeLIMS has been invaluable in the management of our clinical genome sequencing studies. We maintain a publicly available demonstration version of the application for evaluation purposes at http://mendelims.stanford.edu. MendeLIMS is programmed in Ruby on Rails (RoR) and accesses data stored in SQL-compliant relational databases. Software is freely available for non-commercial use at http://dna-discovery.stanford.edu/software/mendelims/.

  4. Climate change and geothermal ecosystems: natural laboratories, sentinel systems, and future refugia.

    Science.gov (United States)

    O'Gorman, Eoin J; Benstead, Jonathan P; Cross, Wyatt F; Friberg, Nikolai; Hood, James M; Johnson, Philip W; Sigurdsson, Bjarni D; Woodward, Guy

    2014-11-01

    Understanding and predicting how global warming affects the structure and functioning of natural ecosystems is a key challenge of the 21st century. Isolated laboratory and field experiments testing global change hypotheses have been criticized for being too small-scale and overly simplistic, whereas surveys are inferential and often confound temperature with other drivers. Research that utilizes natural thermal gradients offers a more promising approach and geothermal ecosystems in particular, which span a range of temperatures within a single biogeographic area, allow us to take the laboratory into nature rather than vice versa. By isolating temperature from other drivers, its ecological effects can be quantified without any loss of realism, and transient and equilibrial responses can be measured in the same system across scales that are not feasible using other empirical methods. Embedding manipulative experiments within geothermal gradients is an especially powerful approach, informing us to what extent small-scale experiments can predict the future behaviour of real ecosystems. Geothermal areas also act as sentinel systems by tracking responses of ecological networks to warming and helping to maintain ecosystem functioning in a changing landscape by providing sources of organisms that are preadapted to different climatic conditions. Here, we highlight the emerging use of geothermal systems in climate change research, identify novel research avenues, and assess their roles for catalysing our understanding of ecological and evolutionary responses to global warming. © 2014 John Wiley & Sons Ltd.

  5. Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Potable Water System Operations Plan

    Energy Technology Data Exchange (ETDEWEB)

    Ocampo, Ruben P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Bellah, Wendy [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-03-04

    The existing Lawrence Livermore National Laboratory (LLNL) Site 300 drinking water system operation schematic is shown in Figures 1 and 2 below. The sources of water are from two Site 300 wells (Well #18 and Well #20) and San Francisco Public Utilities Commission (SFPUC) Hetch-Hetchy water through the Thomas shaft pumping station. Currently, Well #20 with 300 gallons per minute (gpm) pump capacity is the primary source of well water used during the months of September through July, while Well #18 with 225 gpm pump capacity is the source of well water for the month of August. The well water is chlorinated using sodium hypochlorite to provide required residual chlorine throughout Site 300. Well water chlorination is covered in the Lawrence Livermore National Laboratory Experimental Test Site (Site 300) Chlorination Plan (“the Chlorination Plan”; LLNL-TR-642903; current version dated August 2013). The third source of water is the SFPUC Hetch-Hetchy Water System through the Thomas shaft facility with a 150 gpm pump capacity. At the Thomas shaft station the pumped water is treated through SFPUC-owned and operated ultraviolet (UV) reactor disinfection units on its way to Site 300. The Thomas Shaft Hetch- Hetchy water line is connected to the Site 300 water system through the line common to Well pumps #18 and #20 at valve box #1.

  6. Impact of nonintrusive clinical decision support systems on laboratory test utilization in a large academic centre.

    Science.gov (United States)

    Eaton, Kevin P; Chida, Natasha; Apfel, Ariella; Feldman, Leonard; Greenbaum, Adena; Tuddenham, Susan; Kendall, Emily A; Pahwa, Amit

    2018-02-15

    The near-universal prevalence of electronic health records (EHRs) has made the utilization of clinical decision support systems (CDSS) an integral strategy for improving the value of laboratory ordering. Few studies have examined the effectiveness of nonintrusive CDSS on inpatient laboratory utilization in large academic centres. Red blood cell folate, hepatitis C virus viral loads and genotypes, and type and screens were selected for study. We incorporated the appropriate indications for these labs into text that accompanied the laboratory orders in our hospital's EHR. Providers could proceed with the order without additional clicks. An interrupted time-series analysis was performed, and the primary outcome was the rate of tests ordered on all inpatient medicine floors. The rate of folate tests ordered per monthly admissions showed no significant level change at the time of the intervention with only a slight decrease in rate of 0.0109 (P = .07). There was a 43% decrease in the rate of hepatitis C virus tests per monthly admissions immediately after the intervention with a decrease of 0.0135 tests per monthly admissions (P = .02). The rate of type and screens orders per patient days each month had a significant downward trend by 0.114 before the intervention (P = .04) but no significant level change at the time of the intervention or significant change in rate after the intervention. Our study suggests that nonintrusive CDSS should be evaluated for individual laboratory tests to ensure only effective alerts continue to be used so as to avoid increasing EHR fatigue. © 2018 John Wiley & Sons, Ltd.

  7. Mixed methods student evaluation of an online systemic human anatomy course with laboratory.

    Science.gov (United States)

    Attardi, Stefanie M; Choi, Suwhan; Barnett, John; Rogers, Kem A

    2016-05-06

    A fully online section of an existing face-to-face (F2F) systemic human anatomy course with a prosection laboratory was offered for the first time in 2012-2013. Lectures for F2F students (N = 365) were broadcast in both live and archived format to online students (N = 40) using virtual classroom software. Laboratories were delivered online by a teaching assistant who manipulated 3D computer models in the virtual classroom environment. An exploratory sequential mixed methods approach was undertaken to determine the most important deciding factors that drive students' preferences for a given format and then to generate theory on the strengths and weaknesses of the online format. Students (20 online; 310 F2F) volunteered to participate in a crossover period of one week to expose them to the course section in which they were not originally registered. Open ended interviews (20 online; 20 F2F) and quantitative surveys (270 F2F) were conducted following a crossover. Students valued pace control, schedule, and location flexibility of learning from archived materials and being assessed online. In the online laboratory they had difficulty using the 3D models and preferred the unique and hands-on experiences of cadaveric specimens. The F2F environment was conducive to learning in both lecture and laboratory because students felt more engaged by instructors in person and were less distracted by their surroundings. These results suggest the need to improve the online experience by increasing the quality of student-instructor communication and in turn student-content interaction with the 3D models. Anat Sci Educ 9: 272-285. © 2015 American Association of Anatomists. © 2015 American Association of Anatomists.

  8. 76 FR 52042 - Auriga Laboratories, Inc., Curon Medical, Inc., Goldstate Corp., OneWorld Systems, Inc., and...

    Science.gov (United States)

    2011-08-19

    ... COMMISSION Auriga Laboratories, Inc., Curon Medical, Inc., Goldstate Corp., OneWorld Systems, Inc., and... Auriga Laboratories, Inc. because it has not filed any periodic reports since the period ended March 31... information concerning the securities of Curon Medical, Inc. because it has not filed any periodic reports...

  9. Systemic Meglumine Antimoniate in Cutaneous Leishmaniasis of Children: Clinical and Laboratory Complications.

    Science.gov (United States)

    Layegh, Pouran; Khademi, Zeinab; Afzal Aghaee, Monavar; Moghiman, Toktam

    2015-12-01

    Children account for 7%-20% of cutaneous leishmaniasis cases in Iran, but there are few safety data to guide pediatric antiparasitic therapy. We evaluated the clinical and laboratory tolerance of the systemic pentavalent antimonial compound meglumine antimoniate, in 70 Iranian children with cutaneous leishmaniasis. Adverse effects were similar to those seen in adults. © The Author 2014. Published by Oxford University Press on behalf of the Pediatric Infectious Diseases Society. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  10. [Laboratory diagnostics of systemic autoimmune diseases. Part II: rheumatoid arthritis and vasculopathies].

    Science.gov (United States)

    Hartung, K; Seelig, H-P

    2007-05-01

    This is the second part in a series of articles on the laboratory diagnostics of rheumatic diseases. It addresses rheumatoid arthritis, systemic, anti-neutrophil cytoplasmatic antibody (ANCA) positive vasculitides and antiphospholipid-syndrome. The diagnostics of rheumatoid arthritis has been substantially improved by the recently introduced assay for antibodies against citrullinated peptides. In addition, a number of vasculitides can be differentiated by the presence of ANCA. Beta2-glycoprotein I antibodies and lupus anticoagulants are at present the most specific markers for antiphospholipid syndrome. Inflammatory activity can be monitored by determining the levels of acute phase proteins and erythrocyte sedimentation rate, but only in some situations by measuring immunoglobulins and interleukins.

  11. An inclined plane system with microcontroller to determine limb motor function of laboratory animals.

    Science.gov (United States)

    Chang, Ming-Wen; Young, Ming-Shing; Lin, Mao-Tsun

    2008-02-15

    This study describes a high-accuracy inclined plane test system for quantitative measurement of the limb motor function of laboratory rats. The system is built around a microcontroller and uses a stepping motor to drive a ball screw, which changes the angle of the inclined plane. Any of the seven inclination speeds can be selected by the user. Two infrared (IR) LED/detector pairs function as interrupt sensors for objective determination of the moment that the rat loses its grip on the textured flooring of the starting area and slips down the plane. Inclination angle at the moment of IR interrupt (i.e. rat slip) is recorded. A liquid crystal display module shows the inclination speed and the inclination angle. The system can function as a stand alone device but a RS232 port allows connection to a personal computer (PC), so data can be sent directly to hard disk for storage and analysis. Experiments can be controlled by a local keypad or by the connected PC. Advantages of the presented system include easy operation, high accuracy, non-dependence on human observation for determination of slip angle, stand-alone capability, low cost and easy modification of the controlling software for different types of experiments. A fully functional prototype of the system is described. The prototype was used experimentally by a hospital group testing traumatic brain injury experiments, and some of their results are presented for system verification. It is found that the system is stable, accurate and easily used by investigators.

  12. Clinical, laboratory and neuroimage findings in juvenile systemic lupus erythematosus presenting involvement of the nervous system

    OpenAIRE

    Mônica Jaques Spinosa; Márcia Bandeira; Paulo Breno Noronha Liberalesso; Simone Carreiro Vieira; Loris Lady Janz Jr; Eliane Gomes de Sá; Alfredo Löhr Jr.

    2007-01-01

    OBJECTIVE: To characterize neurological involvement in juvenile systemic lupus erythe-matosus. METHOD: The charts of all patients with the diagnosis of systemic lupus erythematosus before the age of 16 years, followed at the Rheumatology Unit of Pequeno Príncipe Hospital, from January 1992 to January 2006, were retrospectively reviewed, highlighting neuropsychiatric aspects. RESULTS: Forty-seven patients were included. Neuropsychiatric syndromes were found 29 (61.7%): seizures (17 / 36.2%), i...

  13. An easy-to-build remote laboratory with data transfer using the Internet School Experimental System

    Science.gov (United States)

    Schauer, František; Lustig, František; Dvořák, Jiří; Ožvoldová, Miroslava

    2008-07-01

    The present state of information communication technology makes it possible to devise and run computer-based e-laboratories accessible to any user with a connection to the Internet, equipped with very simple technical means and making full use of web services. Thus, the way is open for a new strategy of physics education with strongly global features, based on experiment and experimentation. We name this strategy integrated e-learning, and remote experiments across the Internet are the foundation for this strategy. We present both pedagogical and technical reasoning for the remote experiments and outline a simple system based on a server-client approach, and on web services and Java applets. We give here an outline of the prospective remote laboratory system with data transfer using the Internet School Experimental System (ISES) as hardware and ISES WEB Control kit as software. This approach enables the simple construction of remote experiments without building any hardware and virtually no programming, using a paste and copy approach with typical prebuilt blocks such as a camera view, controls, graphs, displays, etc. We have set up and operate at present seven experiments, running round the clock, with more than 12 000 connections since 2005. The experiments are widely used in practical teaching of both university and secondary level physics. The recording of the detailed steps the experimentor takes during the measurement enables detailed study of the psychological aspects of running the experiments. The system is ready for a network of universities to start covering the basic set of physics experiments. In conclusion we summarize the results achieved and experiences of using remote experiments built on the ISES hardware system.

  14. An easy-to-build remote laboratory with data transfer using the Internet School Experimental System

    Energy Technology Data Exchange (ETDEWEB)

    Schauer, Frantisek; Ozvoldova, Miroslava [Trnava University, Faculty of Pedagogy, Department of Physics, Trnava (Slovakia); Lustig, Frantisek; Dvorak, JirI [Charles University, Faculty of Mathematics and Physics, Department of Didactics of Physics, Prague (Czech Republic)], E-mail: fschauer@ft.utb.cz

    2008-07-15

    The present state of information communication technology makes it possible to devise and run computer-based e-laboratories accessible to any user with a connection to the Internet, equipped with very simple technical means and making full use of web services. Thus, the way is open for a new strategy of physics education with strongly global features, based on experiment and experimentation. We name this strategy integrated e-learning, and remote experiments across the Internet are the foundation for this strategy. We present both pedagogical and technical reasoning for the remote experiments and outline a simple system based on a server-client approach, and on web services and Java applets. We give here an outline of the prospective remote laboratory system with data transfer using the Internet School Experimental System (ISES) as hardware and ISES WEB Control kit as software. This approach enables the simple construction of remote experiments without building any hardware and virtually no programming, using a paste and copy approach with typical prebuilt blocks such as a camera view, controls, graphs, displays, etc. We have set up and operate at present seven experiments, running round the clock, with more than 12 000 connections since 2005. The experiments are widely used in practical teaching of both university and secondary level physics. The recording of the detailed steps the experimentor takes during the measurement enables detailed study of the psychological aspects of running the experiments. The system is ready for a network of universities to start covering the basic set of physics experiments. In conclusion we summarize the results achieved and experiences of using remote experiments built on the ISES hardware system.

  15. Simulating Near-Surface Environments of Solar System Bodies in the Laboratory

    Science.gov (United States)

    Donaldson Hanna, Kerri; Bowles, Neil

    2017-04-01

    Thermal infrared (TIR) emissivity measurements are sensitive to a planetary body's near-surface (upper hundreds of microns) environment, porosity and particle size, which make the interpretation of thermal infrared remote sensing observations of planetary surfaces challenging. Thus, well-constrained laboratory TIR measurements of analogue samples for a range of particle sizes, porosities and near-surface environments are needed. Near-surface environments and porosities for a range of solar system bodies can be simulated using facilities within University of Oxford's Planetary Spectroscopy Facility (PSF). The Simulated Lunar Environment Chamber (SLEC) within Oxford's PSF is a vacuum chamber capable of simulating near-surface conditions for a range of solar system bodies by varying atmospheric pressure and incident solar irradiation. By varying the near-surface environment, the thermal gradient in the upper hundreds of microns of the sample is varied, which can affect the position and contrast of diagnostic features in TIR spectra. The atmospheric pressure inside the chamber is varied between 1000, 5 and < 10-4 mbar to simulate Earth, Mars and airless bodies (e.g. the Moon, Mars' moons and asteroids) conditions. The solar-like irradiation is varied by adjusting the power of the halogen lamp until the brightness temperature of the sample is similar to the brightness temperature of the simulated planetary body. Varying the sample packing in the sample cup simulates a range of near-surface porosities. Here we present laboratory emissivity spectra of a suite of well-characterized rock, soil and mineral samples (< 25 microns in particle size) measured under a range of simulated planetary conditions including Earth, Mars, Moon and asteroids. These well-controlled laboratory measurements enable the interpretation of remote sensing observations, which help in determining a planet's surface composition as well as the consolidated nature of its regolith.

  16. Simulating the Near-Surface Environments of Solar System Bodies in the Laboratory

    Science.gov (United States)

    Donaldson Hanna, K. L.; Bowles, N. E.; Greenhagen, B. T.

    2016-12-01

    Thermal infrared (TIR) emissivity measurements are sensitive to a planetary body's near-surface (upper hundreds of microns) environment, porosity and particle size, which make the interpretation of thermal infrared remote sensing observations of planetary surfaces challenging. Thus, well-constrained laboratory TIR measurements of analogue samples for a range of particle sizes, porosities and near-surface environments are needed. Near-surface environments and porosities for a range of solar system bodies can be simulated using facilities within University of Oxford's Planetary Spectroscopy Facility (PSF). The Simulated Lunar Environment Chamber (SLEC) within Oxford's PSF is a vacuum chamber capable of simulating near-surface conditions for a range of solar system bodies by varying atmospheric pressure and incident solar irradiation. By varying the near-surface environment, the thermal gradient in the upper hundreds of microns of the sample is varied, which can affect the position and contrast of diagnostic features in TIR spectra. The atmospheric pressure inside the chamber is varied between 1000, 5 and < 10-4 mbar to simulate Earth, Mars and airless bodies (e.g. the Moon, Mars' moons and asteroids) conditions. The solar-like irradiation is varied by adjusting the power of the halogen lamp until the brightness temperature of the sample is similar to the brightness temperature of the simulated planetary body. Varying the sample packing in the sample cup simulates a range of near-surface porosities. Here we present laboratory emissivity spectra of a suite of well-characterized rock, soil and mineral samples (< 25 mm in particle size) measured under a range of simulated planetary conditions including Earth, Mars, Moon and asteroids. These well-controlled laboratory measurements enable the interpretation of remote sensing observations, which help in determining a planet's surface composition as well as the consolidated nature of its regolith.

  17. Remote Access to Wireless Communications Systems Laboratory--New Technology Approach

    Science.gov (United States)

    Kafadarova, Nadezhda; Sotirov, Sotir; Milev, Mihail

    2012-01-01

    Technology nowadays enables the remote access to laboratory equipment and instruments via Internet. This is especially useful in engineering education, where students can conduct laboratory experiment remotely. Such remote laboratory access can enable students to use expensive laboratory equipment, which is not usually available to students. In…

  18. User needs, benefits, and integration of robotic systems in a space station laboratory

    Science.gov (United States)

    Dodd, W. R.; Badgley, M. B.; Konkel, C. R.

    1989-01-01

    The methodology, results and conclusions of all tasks of the User Needs, Benefits, and Integration Study (UNBIS) of Robotic Systems in a Space Station Laboratory are summarized. Study goals included the determination of user requirements for robotics within the Space Station, United States Laboratory. In Task 1, three experiments were selected to determine user needs and to allow detailed investigation of microgravity requirements. In Task 2, a NASTRAN analysis of Space Station response to robotic disturbances, and acceleration measurement of a standard industrial robot (Intelledex Model 660) resulted in selection of two ranges of microgravity manipulation: Level 1 (10-3 to 10-5 G at greater than 1 Hz) and Level 2 (less than equal 10-6 G at 0.1 Hz). This task included an evaluation of microstepping methods for controlling stepper motors and concluded that an industrial robot actuator can perform milli-G motion without modification. Relative merits of end-effectors and manipulators were studied in Task 3 in order to determine their ability to perform a range of tasks related to the three microgravity experiments. An Effectivity Rating was established for evaluating these robotic system capabilities. Preliminary interface requirements for an orbital flight demonstration were determined in Task 4. Task 5 assessed the impact of robotics.

  19. Pacific Northwest National Laboratory Facility Radionuclide Emissions Units and Sampling Systems

    Energy Technology Data Exchange (ETDEWEB)

    Barnett, J. Matthew; Brown, Jason H.; Walker, Brian A.

    2012-04-01

    Battelle–Pacific Northwest Division operates numerous research and development (R&D) laboratories in Richland, WA, including those associated with Pacific Northwest National Laboratory (PNNL) on the U.S. Department of Energy (DOE)’s Hanford Site and PNNL Site that have the potential for radionuclide air emissions. The National Emission Standard for Hazardous Air Pollutants (NESHAP 40 CFR 61, Subparts H and I) requires an assessment of all emission units that have the potential for radionuclide air emissions. Potential emissions are assessed annually by PNNL staff members. Sampling, monitoring, and other regulatory compliance requirements are designated based upon the potential-to-emit dose criteria found in the regulations. The purpose of this document is to describe the facility radionuclide air emission sampling program and provide current and historical facility emission unit system performance, operation, and design information. For sampled systems, a description of the buildings, exhaust units, control technologies, and sample extraction details is provided for each registered emission unit. Additionally, applicable stack sampler configuration drawings, figures, and photographs are provided. Deregistered emission unit details are provided as necessary for up to 5 years post closure.

  20. Cryosphere Science Outreach using the NASA/JPL Virtual Earth System Laboratory

    Science.gov (United States)

    Larour, E. Y.; Cheng, D. L. C.; Quinn, J.; Halkides, D. J.; Perez, G. L.

    2016-12-01

    Understanding the role of Cryosphere Science within the larger context of Sea Level Rise is both a technical and educational challenge that needs to be addressed if the public at large is to truly understand the implications and consequences of Climate Change. Within this context, we propose a new approach in which scientific tools are used directly inside a mobile/website platform geared towards Education/Outreach. Here, we apply this approach by using the Ice Sheet System Model, a state of the art Cryosphere model developed at NASA, and integrated within a Virtual Earth System Laboratory, with the goal to outreach Cryosphere science to K-12 and College level students. The approach mixes laboratory experiments, interactive classes/lessons on a website, and a simplified interface to a full-fledged instance of ISSM to validate the classes/lessons. This novel approach leverages new insights from the Outreach/Educational community and the interest of new generations in web based technologies and simulation tools, all of it delivered in a seamlessly integrated web platform, relying on a state of the art climate model and live simulations.

  1. IMPLEMENTATION OF DIGITAL LEARNING USING INTERACTIVE MULTIMEDIA IN EXCRETORY SYSTEM WITH VIRTUAL LABORATORY

    Directory of Open Access Journals (Sweden)

    Heru Setiawan

    2015-12-01

    Full Text Available The aim of this study are (1 Developing an interactive multimedia with virtual laboratory in excretory system for senior high school students (2 determine the eligibility of digital multimedia of excretory system (3 determine the effectivity of digital learning using interactive multimedia to improve student’s achievement and student activities of excretory system. This research was conducted in senior high school in Indonesia at SMA 1 Jepon, Blora for 2 month. The research approach using Educational Research and development including: (1research and information collecting (2planning (3 develop a preliminary form of product (4 preliminary field testing, validation of media by experts. (5 main product revision, (6field testing (7operational product revision (8 operational field testing, (9 the final product revision. The results showed that digital media of excretory system with virtual lab is outstanding criteria (91.17% based on 2 expert validation result. Then on prelimenary field testing, the students give outstanding criteria (84.38%, and operation field testing is 92.19%. Digital learning using interactive multimedia also improve student activities, students who achieve the active criteria is 90,63%. Based on the results of research and discussion, can be concluded that digital multimedia of excretory system is very eligible, get possitive response from students and teacher, and effective to improve student achievement and student activity as excretory system media in senior high school.

  2. Cosmology and gravitational waves in the Nordstrom-Vlasov system, a laboratory for Dark Energy

    CERN Document Server

    Corda, Christian

    2013-01-01

    We discuss a cosmological solution of the system which was originally introduced by Calogero and is today popularly known as "Nordstrom-Vlasov system". Although the model is un-physical, its cosmological solution results interesting for the same reasons for which the Nordstrom-Vlasov system was originally introduced in the framework of galactic dynamics. In fact, it represents a theoretical laboratory where one can rigorously study some problems, like the importance of the gravitational waves in the dynamics, which at the present time are not well understood within the physical model of the Einstein-Vlasov system. As the cosmology of the Nordstrom-Vlasov system is founded on a scalar field, a better understanding of the system is important also in the framework of the Dark Energy problem. In fact, various attempts to achieve Dark Energy by using scalar fields are present in the literature. In the solution an analytical expression for the time dependence of the cosmological evolution of the Nordstrom's scalar ...

  3. Software Engineering Laboratory (SEL) data base reporting software user's guide and system description. Volume 1: Introduction and user's guide

    Science.gov (United States)

    1983-01-01

    Reporting software programs provide formatted listings and summary reports of the Software Engineering Laboratory (SEL) data base contents. The operating procedures and system information for 18 different reporting software programs are described. Sample output reports from each program are provided.

  4. Evaluation of Variable Refrigerant Flow Systems Performance on Oak Ridge National Laboratory s Flexible Research Platform: Part 3 Simulation Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Im, Piljae [ORNL; Cho, Heejin [Mississippi State University (MSU); Kim, Dongsu [Mississippi State University (MSU); Cox, Sam [Mississippi State University (MSU)

    2016-08-01

    This report provides second-year project simulation results for the multi-year project titled “Evaluation of Variable Refrigeration Flow (VRF) system on Oak Ridge National Laboratory (ORNL)’s Flexible Research Platform (FRP).”

  5. Two low-level gamma spectrometry systems of the IAEA Safeguards Analytical Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Parus, J.L. [IAEA, SAL, Vienna (Austria); Raab, W. [IAEA, SAL, Vienna (Austria); Donohue, D. [IAEA, SAL, Vienna (Austria); Jansta, V. [IAEA, SAL, Vienna (Austria); Kierzek, J. [IAEA, SAL, Vienna (Austria)

    1997-03-01

    A gamma spectrometry system designed for the measurement of samples with low and medium radioactivity (activity from a few to about 10{sup 4} Bq in the energy range from 25 to 2700 keV) has been installed at the IAEA Safeguards Analytical Laboratory in Seibersdorf. The system consists of 3 low level detectors: (1) n-type coaxial Ge with 42.4% relative efficiency, 1.85 keV FWHM at 1.33 MeV (2) planar Ge with 2000 mm{sup 2} area and 20 mm thickness, 562 eV FWHM at 122 keV (3) NaI(Tl) annulus of 25.4 cm diameter and 25.4 cm height, hole diameter 90 mm. (orig./DG)

  6. Prediction of required ozone dosage for pilot recirculating aquaculture systems based on laboratory studies

    DEFF Research Database (Denmark)

    Spiliotopoulou, Aikaterini; Rojas-Tirado, Paula Andrea; Kaarsholm, Kamilla Marie Speht

    2017-01-01

    suggested that the optimal ozone dosage was 15g O3/ kg feed. Selected water quality parameters were measured, assessing biofilters performance as well as nitrogen and carbon–based compound concentration change during ozonation. Overall, this study contributed to a better understanding of the challenges......In recirculating aquaculture systems (RAS), the water quality changes continuously. Organic and inorganic compounds accumulates creating toxic conditions for the farmed organisms. Ozone improves water quality diminishing significantly both bacteria load and dissolved organic matter. However......, in a non-meticulously designed system, residual ozone might reach the culture tanks causing significant harm to cultured species or excess costs. The aim of the study was to predict the suitable ozone dosage in pilot RAS, for water treatment purposes, based on laboratory studies. The ozone effect on water...

  7. Masters Thesis- Criticality Alarm System Design Guide with Accompanying Alarm System Development for the Radioisotope Production Laboratory in Richland, Washington

    Energy Technology Data Exchange (ETDEWEB)

    Greenfield, Bryce A. [Univ. of New Mexico, Albuquerque, NM (United States)

    2009-12-01

    A detailed instructional manual was created to guide criticality safety engineers through the process of designing a criticality alarm system (CAS) for Department of Energy (DOE) hazard class 1 and 2 facilities. Regulatory and technical requirements were both addressed. A list of design tasks and technical subtasks are thoroughly analyzed to provide concise direction for how to complete the analysis. An example of the application of the design methodology, the Criticality Alarm System developed for the Radioisotope Production Laboratory (RPL) of Richland, Washington is also included. The analysis for RPL utilizes the Monte Carlo code MCNP5 for establishing detector coverage in the facility. Significant improvements to the existing CAS were made that increase the reliability, transparency, and coverage of the system.

  8. A Continuous Extraction and Pumpless Supercritical CO2 Drying System for Laboratory-Scale Aerogel Production

    Directory of Open Access Journals (Sweden)

    István Lázár

    2016-10-01

    Full Text Available Production of aerogels starts with solution chemistry and may end with supercritical carbon dioxide drying, which both require a specialized system. Here we present a complete aerogel production system that was developed and used in our laboratory over the last nine years. Our aim was to develop a supercritical dryer and a protocol, whereby the CO2 pump can be left out, and the entire flow system is operated by the pressure of the CO2 cylinder. Drying pressure and temperature are controlled by the combination of the filling and heating temperatures. A continuous-mode solvent exchange system has also been developed, in which the solvent consumption during the process can be reduced to one-third of the batch method. In the new medium temperature 1.5 L volume supercritical dryer, the temperature is set to a constant 80–82 °C, and the pressure can be in the 90–200 bar range, depending on the conditions. We have performed approximately 200 dryings thus far, and prepared a wide range of monolithic aerogels, from pristine silica aerogels to polysaccharides and collagen. In this paper, we have summarized not only the technical details, but also the work experiences, as well as advantages and disadvantages of the systems.

  9. Response of sago pondweed, a submerged aquatic macrophyte, to herbicides in three laboratory culture systems

    Science.gov (United States)

    Fleming, W.J.; Ailstock, M.S.; Momot, J.J.; Norman, C.M.; Gorsuch, Joseph W.; Lower, William R.; Wang, Wun-cheng; Lewis, M.A.

    1991-01-01

    The phytotoxicity of atrazine, paraquat, glyphosate, and alachlor to sago pondweed (Potamogeton pectinatus), a submerged aquatic macrophyte, was tested under three types of laboratory culture conditions. In each case, tests were conducted in static systems, the test period was four weeks, and herbicide exposure was chronic, resulting from a single addition of herbicide to the test vessels at the beginning of the test period. The three sets of test conditions employed were(1) axenic cultures in 125-mL flasks containing a nutrient media and sucrose; (2) a microcosm system employing 18.9-L buckets containing a sand, shell, and peat substrate; and (3) an algae-free system employing O.95-L jars containing reconstituted freshwater and a nutrient agar substrate. The primary variable measured was biomass production. Plants grew well in all three test systems, with biomass of untreated plants increasing by a factor of about 5 to 6.5 during the four-week test period. Biomass production in response to herbicide exposure differed significantly among culture systems, which demonstrates the need for a standardized testing protocol for evaluating the effects of toxics on submerged aquatic plants.

  10. Surface properties of an indirect composite polymerized with five laboratory light polymerization systems.

    Science.gov (United States)

    Murakami, Mahoko

    2009-06-01

    A study was conducted to evaluate the influence of laboratory light polymerization systems on the post-curing properties of a composite. An indirect composite (Sinfony) was polymerized with five polymerization systems (Visio system, Hyper LII, Pearlcure Light, Twinkle MIII, and UniXS II) using nine polymerization modes. After light exposure, Knoop hardness number, wear depth, and changes in gloss were determined. The highest hardness number was recorded with the use of the Hyper LII (120 s) and Pearlcure Light (120 s) units, whereas the lowest value was obtained with the Visio system and UniXS II (60 s). Six groups demonstrated comparable as well as higher wear resistance to toothbrush abrasion (Hyper LII 60 and 120 s, UniXS II 120 s, Pearlcure Light 60 and 120 s, and Twinkle MIII 120 s), and two groups exhibited lower wear resistance (Visio system and UniXS II 60 s). Gloss of the composite was not dependent on the polymerization mode used before wear testing. However, surface gloss was significantly reduced by toothbrush dentifrice abrasion. Within the limitations of the present experiment, it can be concluded that the Sinfony composite can be polymerized sufficiently with high-intensity light polymerization units.

  11. The semantic smart laboratory: a system for supporting the chemical eScientist.

    Science.gov (United States)

    Hughes, Gareth; Mills, Hugo; De Roure, David; Frey, Jeremy G; Moreau, Luc; Schraefel, M C; Smith, Graham; Zaluska, Ed

    2004-11-21

    One goal of eScience is to enable the end-to-end publication of experiments and results. In the Combechem project we have developed an innovative human-centred system which captures the process of a chemistry experiment from plan to execution. The system comprises an electronic lab book replacement, which has been successfully trialled in a synthetic organic chemistry laboratory, and a flexible back-end storage system. Working closely with the users, we found that a light touch and a high degree of flexibility was required in the user interface. In this paper, we concentrate on the representation and storage of human-scale experiment metadata, introducing an ontology to describe the record of an experiment, and a storage system for the data from our lab book software. Just as the interfaces need to be flexible to cope with whatever a chemist wishes to record, so the back end solutions need to be similarly flexible to store any metadata that may be created. The storage system is based on Semantic Web technologies, such as RDF, and Web Services. It gives a much higher degree of flexibility to the type of metadata it can store, compared to the use of rigid relational databases.

  12. MicroArray Facility: a laboratory information management system with extended support for Nylon based technologies

    Directory of Open Access Journals (Sweden)

    Beaudoing Emmanuel

    2006-09-01

    Full Text Available Abstract Background High throughput gene expression profiling (GEP is becoming a routine technique in life science laboratories. With experimental designs that repeatedly span thousands of genes and hundreds of samples, relying on a dedicated database infrastructure is no longer an option. GEP technology is a fast moving target, with new approaches constantly broadening the field diversity. This technology heterogeneity, compounded by the informatics complexity of GEP databases, means that software developments have so far focused on mainstream techniques, leaving less typical yet established techniques such as Nylon microarrays at best partially supported. Results MAF (MicroArray Facility is the laboratory database system we have developed for managing the design, production and hybridization of spotted microarrays. Although it can support the widely used glass microarrays and oligo-chips, MAF was designed with the specific idiosyncrasies of Nylon based microarrays in mind. Notably single channel radioactive probes, microarray stripping and reuse, vector control hybridizations and spike-in controls are all natively supported by the software suite. MicroArray Facility is MIAME supportive and dynamically provides feedback on missing annotations to help users estimate effective MIAME compliance. Genomic data such as clone identifiers and gene symbols are also directly annotated by MAF software using standard public resources. The MAGE-ML data format is implemented for full data export. Journalized database operations (audit tracking, data anonymization, material traceability and user/project level confidentiality policies are also managed by MAF. Conclusion MicroArray Facility is a complete data management system for microarray producers and end-users. Particular care has been devoted to adequately model Nylon based microarrays. The MAF system, developed and implemented in both private and academic environments, has proved a robust solution for

  13. Interfacing Space Communications and Navigation Network Simulation with Distributed System Integration Laboratories (DSIL)

    Science.gov (United States)

    Jennings, Esther H.; Nguyen, Sam P.; Wang, Shin-Ywan; Woo, Simon S.

    2008-01-01

    NASA's planned Lunar missions will involve multiple NASA centers where each participating center has a specific role and specialization. In this vision, the Constellation program (CxP)'s Distributed System Integration Laboratories (DSIL) architecture consist of multiple System Integration Labs (SILs), with simulators, emulators, testlabs and control centers interacting with each other over a broadband network to perform test and verification for mission scenarios. To support the end-to-end simulation and emulation effort of NASA' exploration initiatives, different NASA centers are interconnected to participate in distributed simulations. Currently, DSIL has interconnections among the following NASA centers: Johnson Space Center (JSC), Kennedy Space Center (KSC), Marshall Space Flight Center (MSFC) and Jet Propulsion Laboratory (JPL). Through interconnections and interactions among different NASA centers, critical resources and data can be shared, while independent simulations can be performed simultaneously at different NASA locations, to effectively utilize the simulation and emulation capabilities at each center. Furthermore, the development of DSIL can maximally leverage the existing project simulation and testing plans. In this work, we describe the specific role and development activities at JPL for Space Communications and Navigation Network (SCaN) simulator using the Multi-mission Advanced Communications Hybrid Environment for Test and Evaluation (MACHETE) tool to simulate communications effects among mission assets. Using MACHETE, different space network configurations among spacecrafts and ground systems of various parameter sets can be simulated. Data that is necessary for tracking, navigation, and guidance of spacecrafts such as Crew Exploration Vehicle (CEV), Crew Launch Vehicle (CLV), and Lunar Relay Satellite (LRS) and orbit calculation data are disseminated to different NASA centers and updated periodically using the High Level Architecture (HLA). In

  14. Measuring Residential Ventilation System Airflows: Part 1 – Laboratory Evaluation of Airflow Meter Devices

    Energy Technology Data Exchange (ETDEWEB)

    Stratton, J. Chris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Turner, W. J. N. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Wray, Craig P. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Walker, Iain S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division

    2012-11-12

    Building codes increasingly require tighter homes and mechanical ventilation per ASHRAE Standard 62.2. These ventilation flows must be measured so that energy is not wasted with over ventilation and occupants’ health is not compromised by under ventilation. Flow hoods are used to measure these ventilation flows, but there is currently no standard specifying the measurement procedure and measurement devices that should be used. This study evaluates the accuracy of six commercially available flow hoods under laboratory conditions configured to emulate a residential mechanical ventilation duct system. The measurements taken with the flow hoods were compared to simultaneous measurements taken by an in-line reference flow meter having a known uncertainty. Results indicate that powered flow hoods yield more accurate measurements than non-powered flow hoods, and that a majority of the flow hoods measured inlet flows more accurately than outlet flows. In several cases, there was little resemblance between the manufacturers’ stated accuracy and the accuracy we found in our laboratory measurements. It is clear that current flow hood calibration procedures may not consider field application variables such as flow asymmetry, flow angle, and flow direction. A new flow hood measurement standard that takes these ‘real world’ conditions into account should be developed to ensure that residential buildings receive the intended ventilation flows.

  15. Measuring Residential Ventilation System Airflows: Part 1 – Laboratory Evaluation of Airflow Meter Devices

    Energy Technology Data Exchange (ETDEWEB)

    Stratton, J. Chris [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Turner, W. J. N. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Wray, Craig P. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division; Walker, Iain S. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Environmental Energy Technologies Division

    2012-11-30

    Building codes increasingly require tighter homes and mechanical ventilation per ASHRAE Standard 62.2. These ventilation flows must be measured so that energy is not wasted with over ventilation and occupants’ health is not compromised by under ventilation. Flow hoods are used to measure these ventilation flows, but there is currently no standard specifying the measurement procedure and measurement devices that should be used. This study evaluates the accuracy of six commercially available flow hoods under laboratory conditions configured to emulate a residential mechanical ventilation duct system. The measurements taken with the flow hoods were compared to simultaneous measurements taken by an in-line reference flow meter having a known uncertainty. Results indicate that powered flow hoods yield more accurate measurements than non-powered flow hoods, and that a majority of the flow hoods measured inlet flows more accurately than outlet flows. In several cases, there was little resemblance between the manufacturers’ stated accuracy and the accuracy we found in our laboratory measurements. It is clear that current flow hood calibration procedures may not consider field application variables such as flow asymmetry, flow angle, and flow direction. A new flow hood measurement standard that takes these ‘real world’ conditions into account should be developed to ensure that residential buildings receive the intended ventilation flows.

  16. A Wildfire Behavior Modeling System at Los Alamos National Laboratory for Operational Applications

    Energy Technology Data Exchange (ETDEWEB)

    S.W. Koch; R.G.Balice

    2004-11-01

    To support efforts to protect facilities and property at Los Alamos National Laboratory from damages caused by wildfire, we completed a multiyear project to develop a system for modeling the behavior of wildfires in the Los Alamos region. This was accomplished by parameterizing the FARSITE wildfire behavior model with locally gathered data representing topography, fuels, and weather conditions from throughout the Los Alamos region. Detailed parameterization was made possible by an extensive monitoring network of permanent plots, weather towers, and other data collection facilities. We also incorporated a database of lightning strikes that can be used individually as repeatable ignition points or can be used as a group in Monte Carlo simulation exercises and in other randomization procedures. The assembled modeling system was subjected to sensitivity analyses and was validated against documented fires, including the Cerro Grande Fire. The resulting modeling system is a valuable tool for research and management. It also complements knowledge based on professional expertise and information gathered from other modeling technologies. However, the modeling system requires frequent updates of the input data layers to produce currently valid results, to adapt to changes in environmental conditions within the Los Alamos region, and to allow for the quick production of model outputs during emergency operations.

  17. The Integrated Cloud-based Environmental Data Management System at Los Alamos National Laboratory - 13391

    Energy Technology Data Exchange (ETDEWEB)

    Schultz Paige, Karen; Gomez, Penny; Patel, Nita P.; EchoHawk, Chris; Dorries, Alison M. [Los Alamos National Laboratory, MS M996, Los Alamos, NM, 87544 (United States)

    2013-07-01

    In today's world, instant access to information is taken for granted. The national labs are no exception; our data users expect immediate access to their data. Los Alamos National Laboratory (LANL) has collected over ten million records, and the data needs to be accessible to scientists as well as the public. The data span a wide range of media, analytes, time periods, formats, and quality and have traditionally existed in scattered databases, making comprehensive work with the data impossible. Recently, LANL has successfully integrated all their environmental data into a single, cloud-based, web-accessible data management system. The system combines data transparency to the public with immediate access required by the technical staff. The use of automatic electronic data validation has been critical to immediate data access while saving millions of dollars and increasing data consistency and quality. The system includes a Google Maps based GIS tool that is simple enough for people to locate potentially contaminated sites near their home or workplace, and complex enough to allow scientists to plot and trend their data at the surface and at depth as well as over time. A variety of formatted reports can be run at any desired frequency to report the most current data available in the data base. The advanced user can also run free form queries of the data base. This data management system has saved LANL time and money, an increasingly important accomplishment during periods of budget cuts with increasing demand for immediate electronic services. (authors)

  18. Performance of a hybrid solar heating system of the solar laboratory at the JRC-ISPRA

    Science.gov (United States)

    van Hattem, D.; Aranovitch, E.; Actis-Dato, P.

    System features and the three year performance data from the solar laboratory at Ispra, which is heated by a heat pump, flat plate collectors, and storage unit are summarized. The heating system has 41 sq m of collector surface, a 50 cu m concrete hot water storage tank, a heat pump with a 17 kW capacity, a floor heating system, and a 2 cu m heat storage as a buffer for the collectors. The building requires 300 W/ deg C for heating and has a peak demand of 9 kW. Chilled water is stored in the underground large tank during the summer for cooling purposes, and one month is alotted to thermally charge the tank before the winter. The addition of the heat pump and storage to the solar flat plate collector system has increased the effective energy gain of the collectors to 1190 MJ/sq m, or 2.5 times the effectiveness without the storage and heat pump.

  19. Developing a new experimental system for an undergraduate laboratory exercise to teach theories of visuomotor learning.

    Science.gov (United States)

    Kasuga, Shoko; Ushiba, Junichi

    2014-01-01

    Humans have a flexible motor ability to adapt their movements to changes in the internal/external environment. For example, using arm-reaching tasks, a number of studies experimentally showed that participants adapt to a novel visuomotor environment. These results helped develop computational models of motor learning implemented in the central nervous system. Despite the importance of such experimental paradigms for exploring the mechanisms of motor learning, because of the cost and preparation time, most students are unable to participate in such experiments. Therefore, in the current study, to help students better understand motor learning theories, we developed a simple finger-reaching experimental system using commonly used laptop PC components with an open-source programming language (Processing Motor Learning Toolkit: PMLT). We found that compared to a commercially available robotic arm-reaching device, our PMLT accomplished similar learning goals (difference in the error reduction between the devices, P = 0.10). In addition, consistent with previous reports from visuomotor learning studies, the participants showed after-effects indicating an adaptation of the motor learning system. The results suggest that PMLT can serve as a new experimental system for an undergraduate laboratory exercise of motor learning theories with minimal time and cost for instructors.

  20. Advanced Stirling Convertor Dual Convertor Controller Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

    Science.gov (United States)

    Dugala, Gina M.; Taylor, Linda M.; Bell, Mark E.; Dolce, James L.; Fraeman, Martin; Frankford, David P.

    2015-01-01

    NASA Glenn Research Center developed a nonnuclear representation of a Radioisotope Power System (RPS) consisting of a pair of Advanced Stirling Convertors (ASCs), Dual Convertor Controller (DCC) EMs (engineering models) 2 and 3, and associated support equipment, which were tested in the Radioisotope Power Systems System Integration Laboratory (RSIL). The DCC was designed by the Johns Hopkins University Applied Physics Laboratory (JHU/APL) to actively control a pair of ASCs. The first phase of testing included a Dual Advanced Stirling Convertor Simulator (DASCS), which was developed by JHU/APL and simulates the operation and electrical behavior of a pair of ASCs in real time via a combination of hardware and software. RSIL provides insight into the electrical interactions between a representative radioisotope power generator, its associated control schemes, and realistic electric system loads. The first phase of integration testing included the following spacecraft bus configurations: capacitive, battery, and super-capacitor. A load profile, created based on data from several missions, tested the RPS's and RSIL's ability to maintain operation during load demands above and below the power provided by the RPS. The integration testing also confirmed the DCC's ability to disconnect from the spacecraft when the bus voltage dipped below 22 volts or exceeded 36 volts. Once operation was verified with the DASCS, the tests were repeated with actual operating ASCs. The goal of this integration testing was to verify operation of the DCC when connected to a spacecraft and to verify the functionality of the newly designed RSIL. The results of these tests are presented in this paper.

  1. EMATS, a robot-based equipment manipulation and transportation system for the columbus free flying laboratory

    Science.gov (United States)

    Putz, P.; Colombina, G.; De Peuter, W.

    1993-03-01

    This paper describes the concept for a robot-based Equipment Manipulation and Transportation System (EMATS) for the Columbus Free Flying Laboratory developed under ESA contract by a study team headed by Dornier. EMATS could not only automatically provide the greater part of the payload facility handling and logistics functions during the unmanned microgravity periods, but also perform unmanned servicing operations in conjunction with various logistics vehicles concepts and assist the crew during manned servicing from the Space Station Freedom and from Hermes. To that end, a variety of telerobotics features are foreseen such as teleoperation and supervised automatic operation from ground or from a small control station aboard the Free Flyer, Hermes, or the Space Station Freedom. The paper summarizes the overall EMATS architecture and illustrates the flexibility of the concept by results from computer graphics simulations.

  2. Laboratory demonstration of image reconstruction for coherent optical system of modular imaging collectors (COSMIC)

    Science.gov (United States)

    Traub, W. A.

    1984-01-01

    The first physical demonstration of the principle of image reconstruction using a set of images from a diffraction-blurred elongated aperture is reported. This is an optical validation of previous theoretical and numerical simulations of the COSMIC telescope array (coherent optical system of modular imaging collectors). The present experiment utilizes 17 diffraction blurred exposures of a laboratory light source, as imaged by a lens covered by a narrow-slit aperture; the aperture is rotated 10 degrees between each exposure. The images are recorded in digitized form by a CCD camera, Fourier transformed, numerically filtered, and added; the sum is then filtered and inverse Fourier transformed to form the final image. The image reconstruction process is found to be stable with respect to uncertainties in values of all physical parameters such as effective wavelength, rotation angle, pointing jitter, and aperture shape. Future experiments will explore the effects of low counting rates, autoguiding on the image, various aperture configurations, and separated optics.

  3. Numerical Analysis of Mixed-Phase Icing Cloud Simulations in the NASA Propulsion Systems Laboratory

    Science.gov (United States)

    Bartkus, Tadas P.; Tsao, Jen-Ching; Struk, Peter M.; Van Zante, Judith F.

    2017-01-01

    This paper describes the development of a numerical model that couples the thermal interaction between ice particles, water droplets, and the flowing gas of an icing wind tunnel for simulation of NASA Glenn Research Centers Propulsion Systems Laboratory (PSL). The ultimate goal of the model is to better understand the complex interactions between the test parameters and have greater confidence in the conditions at the test section of the PSL tunnel. The model attempts to explain the observed changes in test conditions by coupling the conservation of mass and energy equations for both the cloud particles and flowing gas mass. Model predictions were compared to measurements taken during May 2015 testing at PSL, where test conditions varied gas temperature, pressure, velocity and humidity levels, as well as the cloud total water content, particle initial temperature, and particle size distribution.

  4. Ice Crystal Icing Engine Testing in the NASA Glenn Research Center's Propulsion Systems Laboratory: Altitude Investigation

    Science.gov (United States)

    Oliver, Michael J.

    2014-01-01

    The National Aeronautics and Space Administration (NASA) conducted a full scale ice crystal icing turbofan engine test using an obsolete Allied Signal ALF502-R5 engine in the Propulsion Systems Laboratory (PSL) at NASA Glenn Research Center. The test article used was the exact engine that experienced a loss of power event after the ingestion of ice crystals while operating at high altitude during a 1997 Honeywell flight test campaign investigating the turbofan engine ice crystal icing phenomena. The test plan included test points conducted at the known flight test campaign field event pressure altitude and at various pressure altitudes ranging from low to high throughout the engine operating envelope. The test article experienced a loss of power event at each of the altitudes tested. For each pressure altitude test point conducted the ambient static temperature was predicted using a NASA engine icing risk computer model for the given ambient static pressure while maintaining the engine speed.

  5. Development of a laser system of the laboratory AVLIS complex for producing isotopes and radionuclides

    Science.gov (United States)

    D'yachkov, A. B.; Gorkunov, A. A.; Labozin, A. V.; Mironov, S. M.; Panchenko, V. Ya; Firsov, V. A.; Tsvetkov, G. O.

    2018-01-01

    The use of atomic vapour laser isotope separation (AVLIS) for solving a number of urgent problems (formation of 177Lu radionuclides for medical applications, 63Ni radionuclides for betavoltaic power supplies and 150Nd isotope for searching for neutrinoless double β decay and neutrino mass) is considered. An efficient threestep scheme of photoionisation of neodymium atoms through the 50474-cm-1 autoionising state with radiation wavelengths of the corresponding stages of λ1 = 6289.7 Å, λ2 = 5609.4 Å and λ3 = 5972.1 Å is developed. The average saturation intensity of the autoionising transition is ~6 W cm-2, a value consistent with the characteristics of the previously developed photoionisation schemes for lutetium and nickel. A compact laser system for the technological AVLIS complex, designed to produce radionuclides and isotopes under laboratory conditions, is developed based on the experimental results.

  6. Corrosion of carbon steel by bacteria from North Sea offshore seawater injection systems: laboratory investigation.

    Science.gov (United States)

    Stipanicev, Marko; Turcu, Florin; Esnault, Loïc; Rosas, Omar; Basseguy, Régine; Sztyler, Magdalena; Beech, Iwona B

    2014-06-01

    Influence of sulfidogenic bacteria, from a North Sea seawater injection system, on the corrosion of S235JR carbon steel was studied in a flow bioreactor; operating anaerobically for 100days with either inoculated or filtrated seawater. Deposits formed on steel placed in reactors contained magnesium and calcium minerals plus iron sulfide. The dominant biofilm-forming organism was an anaerobic bacterium, genus Caminicella, known to produce hydrogen sulfide and carbon dioxide. Open Circuit Potentials (OCP) of steel in the reactors was, for nearly the entire test duration, in the range -80045), suggested pitting on steel samples within the inoculated environment. However, the actual degree of corrosion could neither be directly correlated with the electrochemical data and nor with the steel corrosion in the filtrated seawater environment. Further laboratory tests are thought to clarify the noticed apparent discrepancies. © 2013.

  7. Laboratory analogue of a supersonic accretion column in a binary star system

    Science.gov (United States)

    Cross, J. E.; Gregori, G.; Foster, J. M.; Graham, P.; Bonnet-Bidaud, J. -M.; Busschaert, C.; Charpentier, N.; Danson, C. N.; Doyle, H. W.; Drake, R. P.; Fyrth, J.; Gumbrell, E. T.; Koenig, M.; Krauland, C.; Kuranz, C. C.; Loupias, B.; Michaut, C.; Mouchet, M.; Patankar, S.; Skidmore, J.; Spindloe, C.; Tubman, E. R.; Woolsey, N.; Yurchak, R.

    2016-01-01

    Astrophysical flows exhibit rich behaviour resulting from the interplay of different forms of energy—gravitational, thermal, magnetic and radiative. For magnetic cataclysmic variable stars, material from a late, main sequence star is pulled onto a highly magnetized (B>10 MG) white dwarf. The magnetic field is sufficiently large to direct the flow as an accretion column onto the poles of the white dwarf, a star subclass known as AM Herculis. A stationary radiative shock is expected to form 100–1,000 km above the surface of the white dwarf, far too small to be resolved with current telescopes. Here we report the results of a laboratory experiment showing the evolution of a reverse shock when both ionization and radiative losses are important. We find that the stand-off position of the shock agrees with radiation hydrodynamic simulations and is consistent, when scaled to AM Herculis star systems, with theoretical predictions. PMID:27291065

  8. Understanding System Utilization as a Limitation Associated with Cybersecurity Laboratories--A Literature Analysis

    Science.gov (United States)

    Pittman, Jason

    2013-01-01

    The use of laboratories as part of cybersecurity education is well evidenced in the existing literature. We are informed about the benefits, different types of laboratories and, in addition, underlying learning theories therein. Existing research also demonstrates that the success of employing cybersecurity laboratory exercises relies upon…

  9. Continuing professional development crediting system for specialists in laboratory medicine within 28 EFLM national societies.

    Science.gov (United States)

    Topic, Elizabeta; Beletic, Andjelo; Zima, Tomas

    2013-01-01

    Continuing professional development (CPD) with corresponding crediting system is recognized as essential for the laboratory medicine specialists to provide optimal service for the patients. Article presents results of the survey evaluating current CPD crediting practice among members of European Federation of Clinical Chemistry and Laboratory Medicine (EFLM). A questionnaire had been forwarded to presidents/national representatives of all EFLM members, with invitation to provide information about CPD programmes and crediting policies, as well as feedback on individual CPD categories, through scoring their relevance. Complete or partial answers were received from 28 of 38 members. In 23 countries, CPD programmes exist and earn credits, with 19 of them offering access to non-medical scientists. CPD activities are evaluated in all participating countries, regardless to the existence of an official CPD programme. Among participating members with mandatory specialists' licensing (22/28), CPD is a prerequisite for relicensing in 13 countries. Main categories recognized as CPD are: continuing education (24 countries), article/book (17/14 countries) authorship and distance learning (14 countries). The highest median score of relevance (20) is allocated to professional training, editor/authorship and official activities in professional organizations, with the first category showing the least variation among scores. Majority of EFLM members have developed CPD programmes, regularly evaluated and accompanied by crediting systems. Programmes differ in accessibility for non-medical scientists and impact on relicensing eligibility. Continuing education, authorship and e-learning are mainly recognized as CPD activities, although the professional training is appreciated as the most important individual CPD category.

  10. Development of a safe ground to space laser propagation system for the optical communications telescope laboratory

    Science.gov (United States)

    Wu, Janet P.

    2003-01-01

    Furthering pursuits in high bandwidth communications to future NASA deep space and neat-Earth probes, the Jet Propulsion Laboratory (JPL) is building the Optical communications Telescope Laboratory (OCTL) atop Table Mountain in Southern California. This R&D optical antenna will be used to develop optical communication strategies for future optical ground stations. Initial experiments to be conducted include propagating high-powered, Q-switched laser beams to retro-reflecting satellites. Yet laser beam propagation from the ground to space is under the cognizance of various government agencies, namely: the Occupational Safety and Health Administration (ISHA) that is responsible for protecting workforce personnel; the Federal Aviation Administration (FAA) responsible for protecting pilots and aircraft; and the Laser Clearinghouse of Space Command responsible for protecting space assets. To ensure that laser beam propagation from the OCTL and future autonomously operated ground stations comply with the guidelines of these organizations, JPL is developing a multi-tiered safety system that will meet the coordination, monitoring, and reporting functions required by the agencies. At Tier 0, laser operators will meet OSHA safety standards for protection and access to the high power lasers area will be restricted and interlocked. Tier 1, the area defined from the telescope dome out to a range of 3.4-km, will utilize long wave infrared camera sensors to alert operators of at risk aircraft in the FAA controlled airspace. Tier 2, defined to extend from 3.4-km out to the aircraft service ceiling in FAA airspace, will detect at risk aircraft by radar. Lastly, beam propagation into space, defined as Tier 3, will require coordination with the Laser Clearinghouse. A detailed description of the four tiers is presented along with the design of the integrated monitoring and beam transmission control system.

  11. Embedded Processor Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Embedded Processor Laboratory provides the means to design, develop, fabricate, and test embedded computers for missile guidance electronics systems in support...

  12. Vehicle Development Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Supports the development of prototype deployment platform vehicles for offboard countermeasure systems.DESCRIPTION: The Vehicle Development Laboratory is...

  13. [Measures to prevent patient identification errors in blood collection/physiological function testing utilizing a laboratory information system].

    Science.gov (United States)

    Shimazu, Chisato; Hoshino, Satoshi; Furukawa, Taiji

    2013-08-01

    We constructed an integrated personal identification workflow chart using both bar code reading and an all in-one laboratory information system. The information system not only handles test data but also the information needed for patient guidance in the laboratory department. The reception terminals at the entrance, displays for patient guidance and patient identification tools at blood-sampling booths are all controlled by the information system. The number of patient identification errors was greatly reduced by the system. However, identification errors have not been abolished in the ultrasound department. After re-evaluation of the patient identification process in this department, we recognized that the major reason for the errors came from excessive identification workflow. Ordinarily, an ultrasound test requires patient identification 3 times, because 3 different systems are required during the entire test process, i.e. ultrasound modality system, laboratory information system and a system for producing reports. We are trying to connect the 3 different systems to develop a one-time identification workflow, but it is not a simple task and has not been completed yet. Utilization of the laboratory information system is effective, but is not yet perfect for patient identification. The most fundamental procedure for patient identification is to ask a person's name even today. Everyday checks in the ordinary workflow and everyone's participation in safety-management activity are important for the prevention of patient identification errors.

  14. Advanced Optical Diagnostics for Ice Crystal Cloud Measurements in the NASA Glenn Propulsion Systems Laboratory

    Science.gov (United States)

    Bencic, Timothy J.; Fagan, Amy; Van Zante, Judith F.; Kirkegaard, Jonathan P.; Rohler, David P.; Maniyedath, Arjun; Izen, Steven H.

    2013-01-01

    A light extinction tomography technique has been developed to monitor ice water clouds upstream of a direct connected engine in the Propulsion Systems Laboratory (PSL) at NASA Glenn Research Center (GRC). The system consists of 60 laser diodes with sheet generating optics and 120 detectors mounted around a 36-inch diameter ring. The sources are pulsed sequentially while the detectors acquire line-of-sight extinction data for each laser pulse. Using computed tomography algorithms, the extinction data are analyzed to produce a plot of the relative water content in the measurement plane. To target the low-spatial-frequency nature of ice water clouds, unique tomography algorithms were developed using filtered back-projection methods and direct inversion methods that use Gaussian basis functions. With the availability of a priori knowledge of the mean droplet size and the total water content at some point in the measurement plane, the tomography system can provide near real-time in-situ quantitative full-field total water content data at a measurement plane approximately 5 feet upstream of the engine inlet. Results from ice crystal clouds in the PSL are presented. In addition to the optical tomography technique, laser sheet imaging has also been applied in the PSL to provide planar ice cloud uniformity and relative water content data during facility calibration before the tomography system was available and also as validation data for the tomography system. A comparison between the laser sheet system and light extinction tomography resulting data are also presented. Very good agreement of imaged intensity and water content is demonstrated for both techniques. Also, comparative studies between the two techniques show excellent agreement in calculation of bulk total water content averaged over the center of the pipe.

  15. The Protein Information Management System (PiMS): a generic tool for any structural biology research laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Morris, Chris [STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Pajon, Anne [Wellcome Trust Genome Campus, Hinxton CB10 1SD (United Kingdom); Griffiths, Susanne L. [University of York, Heslington, York YO10 5DD (United Kingdom); Daniel, Ed [STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Savitsky, Marc [University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Lin, Bill [STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Diprose, Jonathan M. [University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Wilter da Silva, Alan [Wellcome Trust Genome Campus, Hinxton CB10 1SD (United Kingdom); Pilicheva, Katya [University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Troshin, Peter [STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Niekerk, Johannes van [University of Dundee, Dundee DD1 5EH, Scotland (United Kingdom); Isaacs, Neil [University of Glasgow, Glasgow G12 8QQ, Scotland (United Kingdom); Naismith, James [University of St Andrews, St Andrews, Fife KY16 9ST, Scotland (United Kingdom); Nave, Colin; Blake, Richard [STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom); Wilson, Keith S. [University of York, Heslington, York YO10 5DD (United Kingdom); Stuart, David I. [University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); Henrick, Kim [Wellcome Trust Genome Campus, Hinxton CB10 1SD (United Kingdom); Esnouf, Robert M., E-mail: robert@strubi.ox.ac.uk [University of Oxford, Roosevelt Drive, Oxford OX3 7BN (United Kingdom); STFC Daresbury Laboratory, Warrington WA4 4AD (United Kingdom)

    2011-04-01

    The Protein Information Management System (PiMS) is described together with a discussion of how its features make it well suited to laboratories of all sizes. The techniques used in protein production and structural biology have been developing rapidly, but techniques for recording the laboratory information produced have not kept pace. One approach is the development of laboratory information-management systems (LIMS), which typically use a relational database schema to model and store results from a laboratory workflow. The underlying philosophy and implementation of the Protein Information Management System (PiMS), a LIMS development specifically targeted at the flexible and unpredictable workflows of protein-production research laboratories of all scales, is described. PiMS is a web-based Java application that uses either Postgres or Oracle as the underlying relational database-management system. PiMS is available under a free licence to all academic laboratories either for local installation or for use as a managed service.

  16. Development and implementation of the Caribbean Laboratory Quality Management Systems Stepwise Improvement Process (LQMS-SIP) Towards Accreditation

    Science.gov (United States)

    Alemnji, George; Edghill, Lisa; Wallace-Sankarsingh, Sacha; Albalak, Rachel; Cognat, Sebastien; Nkengasong, John; Gabastou, Jean-Marc

    2017-01-01

    Background Implementing quality management systems and accrediting laboratories in the Caribbean has been a challenge. Objectives We report the development of a stepwise process for quality systems improvement in the Caribbean Region. Methods The Caribbean Laboratory Stakeholders met under a joint Pan American Health Organization/US Centers for Disease Control and Prevention initiative and developed a user-friendly framework called ‘Laboratory Quality Management System – Stepwise Improvement Process (LQMS-SIP) Towards Accreditation’ to support countries in strengthening laboratory services through a stepwise approach toward fulfilling the ISO 15189: 2012 requirements. Results This approach consists of a three-tiered framework. Tier 1 represents the minimum requirements corresponding to the mandatory criteria for obtaining a licence from the Ministry of Health of the participating country. The next two tiers are quality improvement milestones that are achieved through the implementation of specific quality management system requirements. Laboratories that meet the requirements of the three tiers will be encouraged to apply for accreditation. The Caribbean Regional Organisation for Standards and Quality hosts the LQMS-SIP Secretariat and will work with countries, including the Ministry of Health and stakeholders, including laboratory staff, to coordinate and implement LQMS-SIP activities. The Caribbean Public Health Agency will coordinate and advocate for the LQMS-SIP implementation. Conclusion This article presents the Caribbean LQMS-SIP framework and describes how it will be implemented among various countries in the region to achieve quality improvement. PMID:28879149

  17. Development and implementation of the Caribbean Laboratory Quality Management Systems Stepwise Improvement Process (LQMS-SIP Towards Accreditation

    Directory of Open Access Journals (Sweden)

    George Alemnji

    2017-02-01

    Full Text Available Background: Implementing quality management systems and accrediting laboratories in the Caribbean has been a challenge.Objectives: We report the development of a stepwise process for quality systems improvement in the Caribbean Region.Methods: The Caribbean Laboratory Stakeholders met under a joint Pan American Health Organization/US Centers for Disease Control and Prevention initiative and developed a user-friendly framework called ‘Laboratory Quality Management System – Stepwise Improvement Process (LQMS-SIP Towards Accreditation’ to support countries in strengthening laboratory services through a stepwise approach toward fulfilling the ISO 15189: 2012 requirements.Results: This approach consists of a three-tiered framework. Tier 1 represents the minimum requirements corresponding to the mandatory criteria for obtaining a licence from the Ministry of Health of the participating country. The next two tiers are quality improvement milestones that are achieved through the implementation of specific quality management system requirements. Laboratories that meet the requirements of the three tiers will be encouraged to apply for accreditation. The Caribbean Regional Organisation for Standards and Quality hosts the LQMS-SIP Secretariat and will work with countries, including the Ministry of Health and stakeholders, including laboratory staff, to coordinate and implement LQMS-SIP activities. The Caribbean Public Health Agency will coordinate and advocate for the LQMS-SIP implementation.Conclusion: This article presents the Caribbean LQMS-SIP framework and describes how it will be implemented among various countries in the region to achieve quality improvement.

  18. Novel laboratory approaches to multi-purpose aquatic bioregenerative closed-loop food production systems

    Science.gov (United States)

    Blüm, V.; Andriske, M.; Kreuzberg, K.; Paassen, U.; Schreibman, M. P.; Voeste, D.

    Based on the construction principle of the Closed Equilibrated Biological Aquatic System (C.E.B.A.S.) two novel combined animal-plant production systems were developed in laboratory scale the first of which is dedicated to mid-term operation in closed state up to two years. In principle both consist of the "classic" C.E.B.A.S. subcomponents: animal tank (Zoological Component), plant cultivators (Botanical Component), ammonia converting bacteria filter (Microbial Component) and data acquisition/control unit (Electronical Component). The innovative approach in the first system is the utilization of minimally three aquatic plant cultivators for different species. In this one the animal tank has a volume of about 160 liters and is constructed as an "endless-way system" surronding a central unit containing the heat exchanger and the bacteria filter with volumes of about 1.5 liters each. A suspension plant cultivator (1 liter) for the edible duckweed Wolffia arrhiza is externally connected. The second plant cultivator is a meandric microalgal bioreactor for filamentous green algae. The third plant growth facilitiy is a chamber with about 2.5 liters volume for cultivation of the "traditional" C.E.B.A.S. plant species, the rootless buoyant Ceratophyllum demersum. Both latter units are illuminated with 9 W fluorescent lamps. In the current experiment the animal tank contains the live-bearing teleost fish Xiphophorus helleri and the small pulmonate water snail Biomphalaria glabrata because their physiological adaptation to the closed system conditions is well known from many previous C.E.B.A.S. experiments. The water temperature is maintained at 25 °C and the oxygen level is regulated between 4 and 7 mg/1 by switching on and off the plant cultivator illuminations according to a suitable pattern thus utilizing solely the oxygen produced by photosynthesis. The animals and the micoorganisms of filter and bioflim provide the plants with a sufficient amount of carbon dioxide

  19. Accuracy in HIV Rapid Testing among Laboratory and Non-laboratory Personnel in Zambia: Observations from the National HIV Proficiency Testing System.

    Directory of Open Access Journals (Sweden)

    Sheila Mwangala

    Full Text Available Despite rapid task-shifting and scale-up of HIV testing services in high HIV prevalence countries, studies evaluating accuracy remain limited. This study aimed to assess overall accuracy level and factors associated with accuracy in HIV rapid testing in Zambia.Accuracy was investigated among rural and urban HIV testing sites participating in two annual national HIV proficiency testing (PT exercises conducted in 2009 (n = 282 sites and 2010 (n = 488 sites. Testers included lay counselors, nurses, laboratory personnel and others. PT panels of five dry tube specimens (DTS were issued to testing sites by the national reference laboratory (NRL. Site accuracy level was assessed by comparison of reported results to the expected results. Non-parametric rank tests and multiple linear regression models were used to assess variation in accuracy between PT cycles and between tester groups, and to examine factors associated with accuracy respectively.Overall accuracy level was 93.1% (95% CI: 91.2-94.9 in 2009 and 96.9% (95% CI: 96.1-97.8 in 2010. Differences in accuracy were seen between the tester groups in 2009 with laboratory personnel being more accurate than non-laboratory personnel, while in 2010 no differences were seen. In both PT exercises, lay counselors and nurses had more difficulties interpreting results, with more occurrences of false-negative, false-positive and indeterminate results. Having received the standard HIV rapid testing training and adherence to the national HIV testing algorithm were positively associated with accuracy.The study showed an improvement in tester group and overall accuracy from the first PT exercise to the next. Average number of incorrect test results per 1000 tests performed was reduced from 69 to 31. Further improvement is needed, however, and the national HIV proficiency testing system seems to be an important tool in this regard, which should be continued and needs to be urgently strengthened.

  20. A laboratory based system for laue micro x-ray diffraction.

    Science.gov (United States)

    Lynch, P A; Stevenson, A W; Liang, D; Parry, D; Wilkins, S; Tamura, N

    2007-02-01

    A laboratory diffraction system capable of illuminating individual grains in a polycrystalline matrix is described. Using a microfocus x-ray source equipped with a tungsten anode and prefigured monocapillary optic, a micro-x-ray diffraction system with a 10 microm beam was developed. The beam profile generated by the ellipsoidal capillary was determined using the "knife edge" approach. Measurement of the capillary performance, indicated a beam divergence of 14 mrad and a useable energy bandpass from 5.5 to 19 keV. Utilizing the polychromatic nature of the incident x-ray beam and application of the Laue indexing software package X-Ray Micro-Diffraction Analysis Software, the orientation and deviatoric strain of single grains in a polycrystalline material can be studied. To highlight the system potential the grain orientation and strain distribution of individual grains in a polycrystalline magnesium alloy (Mg 0.2 wt % Nd) was mapped before and after tensile loading. A basal (0002) orientation was identified in the as-rolled annealed alloy; after tensile loading some grains were observed to undergo an orientation change of 30 degrees with respect to (0002). The applied uniaxial load was measured as an increase in the deviatoric tensile strain parallel to the load axis.

  1. Idaho National Laboratory Integrated Safety Management System FY 2012 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Farren Hunt

    2012-12-01

    Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for fiscal year (FY) 2013. Results of the FY 2012 annual effectiveness review demonstrated that the INL’s ISMS program was significantly strengthened. Actions implemented by the INL demonstrate that the overall Integrated Safety Management System is sound and ensures safe and successful performance of work while protecting workers, the public, and environment. This report also provides several opportunities for improvement that will help further strengthen the ISM Program and the pursuit of safety excellence. Demonstrated leadership and commitment, continued surveillance, and dedicated resources have been instrumental in maturing a sound ISMS program. Based upon interviews with personnel, reviews of assurance activities, and analysis of ISMS process implementation, this effectiveness review concludes that ISM is institutionalized and is “Effective”.

  2. Idaho National Laboratory Integrated Safety Management System FY 2016 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, Farren J. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-12-01

    Idaho National Laboratory’s (INL’s) Integrated Safety Management System (ISMS) effectiveness review of fiscal year (FY) 2016 shows that INL has integrated management programs and safety elements throughout the oversight and operational activities performed at INL. The significant maturity of Contractor Assurance System (CAS) processes, as demonstrated across INL’s management systems and periodic reporting through the Management Review Meeting process, over the past two years has provided INL with current real-time understanding and knowledge pertaining to the health of the institution. INL’s sustained excellence of the Integrated Safety and effective implementation of the Worker Safety and Health Program is also evidenced by other external validations and key indicators. In particular, external validations include VPP, ISO 14001, DOELAP accreditation, and key Laboratory level indicators such as ORPS (number, event frequency and severity); injury/illness indicators such as Days Away, Restricted and Transfer (DART) case rate, back & shoulder metric and open reporting indicators, demonstrate a continuous positive trend and therefore improved operational performance over the last few years. These indicators are also reflective of the Laboratory’s overall organizational and safety culture improvement. Notably, there has also been a step change in ESH&Q Leadership actions that have been recognized both locally and complex-wide. Notwithstanding, Laboratory management continues to monitor and take action on lower level negative trends in numerous areas including: Conduct of Operations, Work Control, Work Site Analysis, Risk Assessment, LO/TO, Fire Protection, and Life Safety Systems, to mention a few. While the number of severe injury cases has decreased, as evidenced by the reduction in the DART case rate, the two hand injuries and the fire truck/ambulance accident were of particular concern. Aggressive actions continue in order to understand the causes and

  3. Lincoln Laboratory Grid

    Data.gov (United States)

    Federal Laboratory Consortium — The Lincoln Laboratory Grid (LLGrid) is an interactive, on-demand parallel computing system that uses a large computing cluster to enable Laboratory researchers to...

  4. Method for automatization of the alignment of a laboratory based x-ray phase contrast edge illumination system.

    Science.gov (United States)

    Millard, T P; Endrizzi, M; Ignatyev, K; Hagen, C K; Munro, P R T; Speller, R D; Olivo, A

    2013-08-01

    Here we present a general alignment algorithm for an edge illumination x-ray phase contrast imaging system, which is used with the laboratory systems developed at UCL. It has the flexibility to be used with all current mask designs, and could also be applied to future synchrotron based systems. The algorithm has proved to be robust experimentally, and can be used for the automatization of future commercial systems through automatic alignment and alignment correction.

  5. Advanced Stirling Convertor Control Unit Testing at NASA Glenn Research Center in the Radioisotope Power Systems System Integration Laboratory

    Science.gov (United States)

    Dugala, Gina M.; Taylor, Linda M.; Kussmaul, Michael; Casciani, Michael; Brown, Gregory; Wiser, Joel

    2017-01-01

    Future NASA missions could include establishing Lunar or Martian base camps, exploring Jupiters moons and travelling beyond where generating power from sunlight may be limited. Radioisotope Power Systems (RPS) provide a dependable power source for missions where inadequate sunlight or operational requirements make other power systems impractical. Over the past decade, NASA Glenn Research Center (GRC) has been supporting the development of RPSs. The Advanced Stirling Radioisotope Generator (ASRG) utilized a pair of Advanced Stirling Convertors (ASC). While flight development of the ASRG has been cancelled, much of the technology and hardware continued development and testing to guide future activities. Specifically, a controller for the convertor(s) is an integral part of a Stirling-based RPS. For the ASRG design, the controller maintains stable operation of the convertors, regulates the alternating current produced by the linear alternator of the convertor, provides a specified direct current output voltage for the spacecraft, synchronizes the piston motion of the two convertors in order to minimize vibration as well as manage and maintain operation with a stable piston amplitude and hot end temperature. It not only provides power to the spacecraft but also must regulate convertor operation to avoid damage to internal components and maintain safe thermal conditions after fueling. Lockheed Martin Coherent Technologies has designed, developed and tested an Engineering Development Unit (EDU) Advanced Stirling Convertor Control Unit (ACU) to support this effort. GRC used the ACU EDU as part of its non-nuclear representation of a RPS which also consists of a pair of Dual Advanced Stirling Convertor Simulator (DASCS), and associated support equipment to perform a test in the Radioisotope Power Systems System Integration Laboratory (RSIL). The RSIL was designed and built to evaluate hardware utilizing RPS technology. The RSIL provides insight into the electrical

  6. Improvement of the quality of work in a biochemistry laboratory via measurement system analysis.

    Science.gov (United States)

    Chen, Ming-Shu; Liao, Chen-Mao; Wu, Ming-Hsun; Lin, Chih-Ming

    2016-10-31

    An adequate and continuous monitoring of operational variations can effectively reduce the uncertainty and enhance the quality of laboratory reports. This study applied the evaluation rule of the measurement system analysis (MSA) method to estimate the quality of work conducted in a biochemistry laboratory. Using the gauge repeatability & reproducibility (GR&R) approach, variations in quality control (QC) data among medical technicians in conducting measurements of five biochemical items, namely, serum glucose (GLU), aspartate aminotransferase (AST), uric acid (UA), sodium (Na) and chloride (Cl), were evaluated. The measurements of the five biochemical items showed different levels of variance among the different technicians, with the variances in GLU measurements being higher than those for the other four items. The ratios of precision-to-tolerance (P/T) for Na, Cl and GLU were all above 0.5, implying inadequate gauge capability. The product variation contribution of Na was large (75.45% and 31.24% in normal and abnormal QC levels, respectively), which showed that the impact of insufficient usage of reagents could not be excluded. With regard to reproducibility, high contributions (of more than 30%) of variation for the selected items were found. These high operator variation levels implied that the possibility of inadequate gauge capacity could not be excluded. The analysis of variance (ANOVA) of GR&R showed that the operator variations in GLU measurements were significant (F=5.296, P=0.001 in the normal level and F=3.399, P=0.015 in the abnormal level, respectively). In addition to operator variations, product variations of Na were also significant for both QC levels. The heterogeneity of variance for the five technicians showed significant differences for the Na and Cl measurements in the normal QC level. The accuracy of QC for five technicians was identified for further operational improvement. This study revealed that MSA can be used to evaluate product and

  7. Building an internet-based workflow system - the case of Lawrence Livermore National Laboratories` Zephyr project

    Energy Technology Data Exchange (ETDEWEB)

    Jordan, C. W., LLNL

    1998-04-01

    Lawrence Livermore National Laboratories` Zephyr System provides a showcase for the ways in which emerging technologies can help streamline procurement processes and improve the coordination between participants in engineering projects by allowing collaboration in ways that have not been possible before. The project also shows the success of a highly pragmatic approach that was initiated by the end user community, and that intentionally covered standard situations, rather than aiming at also automating the exceptions. By helping push purchasing responsibilities down to the end user, thereby greatly reducing the involvement of the purchasing department in operational activities, it was possible to streamline the process significantly resulting in time savings of up to 90%, major cost reductions, and improved quality. Left with less day-to- day purchasing operations, the purchasing department has more time for strategic tasks such as selecting and pre-qualifying new suppliers, negotiating blanket orders, or implementing new procurement systems. The case shows once more that the use of information technologies can result in major benefits when aligned with organizational adjustments.

  8. Measuring the spatial resolution of an optical system in an undergraduate optics laboratory

    Science.gov (United States)

    Leung, Calvin; Donnelly, T. D.

    2017-06-01

    Two methods of quantifying the spatial resolution of a camera are described, performed, and compared, with the objective of designing an imaging-system experiment for students in an undergraduate optics laboratory. With the goal of characterizing the resolution of a typical digital single-lens reflex (DSLR) camera, we motivate, introduce, and show agreement between traditional test-target contrast measurements and the technique of using Fourier analysis to obtain the modulation transfer function (MTF). The advantages and drawbacks of each method are compared. Finally, we explore the rich optical physics at work in the camera system by calculating the MTF as a function of wavelength and f-number. For example, we find that the Canon 40D demonstrates better spatial resolution at short wavelengths, in accordance with scalar diffraction theory, but is not diffraction-limited, being significantly affected by spherical aberration. The experiment and data analysis routines described here can be built and written in an undergraduate optics lab setting.

  9. Idaho National Laboratory Integrated Safety Management System FY 2013 Effectiveness Review and Declaration Report

    Energy Technology Data Exchange (ETDEWEB)

    Hunt, Farren [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2013-12-01

    Idaho National Laboratory (INL) performed an Annual Effectiveness Review of the Integrated Safety Management System (ISMS), per 48 Code of Federal Regulations (CFR) 970.5223 1, “Integration of Environment, Safety and Health into Work Planning and Execution.” The annual review assessed Integrated Safety Management (ISM) effectiveness, provided feedback to maintain system integrity, and identified target areas for focused improvements and assessments for Fiscal Year (FY) 2014. Results of the FY 2013 annual effectiveness review demonstrate that the INL’s ISMS program is “Effective” and continually improving and shows signs of being significantly strengthened. Although there have been unacceptable serious events in the past, there has also been significant attention, dedication, and resources focused on improvement, lessons learned and future prevention. BEA’s strategy of focusing on these improvements includes extensive action and improvement plans that include PLN 4030, “INL Sustained Operational Improvement Plan, PLN 4058, “MFC Strategic Excellence Plan,” PLN 4141, “ATR Sustained Excellence Plan,” and PLN 4145, “Radiological Control Road to Excellence,” and the development of LWP 20000, “Conduct of Research.” As a result of these action plans, coupled with other assurance activities and metrics, significant improvement in operational performance, organizational competence, management oversight and a reduction in the number of operational events is being realized. In short, the realization of the fifth core function of ISMS (feedback and continuous improvement) and the associated benefits are apparent.

  10. Development of Laboratory Experimental System to Clarify Solar Wind Charge Exchange Mechanism with TES Microcalorimeter

    Science.gov (United States)

    Enoki, T.; Ishisaki, Y.; Akamatsu, H.; Ezoe, Y.; Ohashi, T.; Kanda, T.; Ishida, T.; Tanuma, H.; Ohashi, H.; Shinozaki, K.; Mitsuda, K.

    2012-06-01

    Significant fraction of the cosmic diffuse soft X-ray emission (0.1-1 keV) is caused by the Solar Wind Charge eXchange (SWCX) process between the solar wind ion (C q+, N q+, O q+ etc.) and the interplanetary neutral matter. It is difficult to identify spectral features of SWCX with the spectral resolution of existing X-ray astronomy satellites. We are developing a laboratory experimental system with transition edge sensor (TES) X-ray microcalorimeters, in order to clarify the SWCX mechanism. This experiment is designed to measure Charge eXchange (CX) X-rays using Electron Cyclotron Resonance Ion Source (ECRIS) that generates multi-charged ions. Emission lines (OVIII: 2p→1s; 654 eV) by CX between O8+ and neutral He atom is aimed to be measured with energy resolution better than 10 eV. The TES microcalorimeter is cooled by a double-stage adiabatic demagnetization refrigerator (DADR), however, our TES microcalorimeter are not working potentially due to magnetic field contamination. This paper reports our experimental system, present results, and future prospects.

  11. Infinite-dimensional approach to system identification of Space Control Laboratory Experiment (SCOLE)

    Science.gov (United States)

    Hossain, S. A.; Lee, K. Y.

    1988-01-01

    The identification of a unique set of system parameters in large space structures poses a significant new problem in control technology. Presented is an infinite-dimensional identification scheme to determine system parameters in large flexible structures in space. The method retains the distributed nature of the structure throughout the development of the algorithm and a finite-element approximation is used only to implement the algorithm. This approach eliminates many problems associated with model truncation used in other methods of identification. The identification is formulated in Hilbert space and an optimal control technique is used to minimize weighted least squares of error between the actual and the model data. A variational approach is used to solve the problem. A costate equation, gradients of parameter variations and conditions for optimal estimates are obtained. Computer simulation studies are conducted using a shuttle-attached antenna configuration, more popularly known as the Space Control Laboratory Experiment (SCOLE) as an example. Numerical results show a close match between the estimated and true values of the parameters.

  12. The Collaborative Cross at Oak Ridge National Laboratory: developing a powerful resource for systems genetics

    Energy Technology Data Exchange (ETDEWEB)

    Chesler, Elissa J [ORNL; Branstetter, Lisa R [ORNL; Churchill, Gary A [Jackson Laboratory, The, Bar Harbor, ME; Culiat, Cymbeline T [ORNL; Galloway, Leslie D [ORNL; Jackson, Barbara L [ORNL; Johnson, Dabney K [ORNL; Miller, Darla R [ORNL; Philip, Vivek M [ORNL; Threadgill, David [University of North Carolina, Chapel Hill; Voy, Brynn H [ORNL; Williams, Robert [University of Tennessee Health Science Center, Memphis; Manly, Kenneth [University of Tennessee Health Science Center, Memphis

    2008-01-01

    Complex traits and disease co-morbidity in humans and in model organisms are the result of naturally occurring polymorphisms that interact with each other and with the environment. To ensure the availability of the resources needed to investigate biomolecular networks and ultimately systems level phenotypes, we have initiated breeding of a new genetic reference population of mice, the Collaborative Cross. This population has been designed to optimally support systems genetics analysis. Its novel and important features include high levels of genetic diversity, a large population size to ensure sufficient power in high-dimensional studies, and high mapping precision through accumulation of independent recombination events. Implementation of the Collaborative Cross has been in progress at the Oak Ridge National Laboratory (ORNL) since May 2005. This is achieved through a software assisted breeding program with fully traceable lineages, performed in a uniform environment. Currently, there are 650 lines in production with almost 200 lines over seven generations of inbreeding. Retired breeders enter a high-throughput phenotyping protocol and DNA samples are banked for analysis of recombination history, allele loss, and population structure. Herein we present a progress report of the Collaborative Cross breeding program at ORNL and a description of the kinds of investigations that this resource will support.

  13. Recirculation System for Geothermal Energy Recovery in Sedimentary Formations: Laboratory Experiments and Numerical Simulations

    Science.gov (United States)

    Elkhoury, J. E.; Detwiler, R. L.; Serajian, V.; Bruno, M. S.

    2012-12-01

    Geothermal energy resources are more widespread than previously thought and have the potential for providing a significant amount of sustainable clean energy worldwide. In particular, hot permeable sedimentary formations provide many advantages over traditional geothermal recovery and enhanced geothermal systems in low permeability crystalline formations. These include: (1) eliminating the need for hydraulic fracturing, (2) significant reduction in risk for induced seismicity, (3) reducing the need for surface wastewater disposal, (4) contributing to decreases in greenhouse gases, and (5) potential use for CO2 sequestration. Advances in horizontal drilling, completion, and production technology from the oil and gas industry can now be applied to unlock these geothermal resources. Here, we present experimental results from a laboratory scale circulation system and numerical simulations aimed at quantifying the heat transfer capacity of sedimentary rocks. Our experiments consist of fluid flow through a saturated and pressurized sedimentary disc of 23-cm diameter and 3.8-cm thickness heated along its circumference at a constant temperature. Injection and production ports are 7.6-cm apart in the center of the disc. We used DI de-aired water and mineral oil as working fluids and explored temperatures from 20 to 150 oC and flow rates from 2 to 30 ml/min. We performed experiments on sandstone samples (Castlegate and Kirby) with different porosity, permeability and thermal conductivity to evaluate the effect of hydraulic and thermal properties on the heat transfer capacity of sediments. The producing fluid temperature followed an exponential form with time scale transients between 15 and 45 min. Steady state outflow temperatures varied between 60% and 95% of the set boundary temperature, higher percentages were observed for lower temperatures and flow rates. We used the flow and heat transport simulator TOUGH2 to develop a numerical model of our laboratory setting. Given

  14. Iron oxides stimulate microbial monochlorobenzene in situ transformation in constructed wetlands and laboratory systems

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Marie; Wolfram, Diana; Birkigt, Jan [Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental Research — UFZ, Permoserstrasse 15, 04318 Leipzig (Germany); Ahlheim, Jörg [Department of Groundwater Remediation, Helmholtz Centre for Environmental Research — UFZ, Permoserstrasse 15, 04318 Leipzig (Germany); Paschke, Heidrun [Department of Analytical Chemistry, Helmholtz Centre for Environmental Research — UFZ, Permoserstrasse 15, 04318 Leipzig (Germany); Richnow, Hans-Hermann [Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental Research — UFZ, Permoserstrasse 15, 04318 Leipzig (Germany); Nijenhuis, Ivonne, E-mail: ivonne.nijenhuis@ufz.de [Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental Research — UFZ, Permoserstrasse 15, 04318 Leipzig (Germany)

    2014-02-01

    Natural wetlands are transition zones between anoxic ground and oxic surface water which may enhance the (bio)transformation potential for recalcitrant chloro-organic contaminants due to the unique geochemical conditions and gradients. Monochlorobenzene (MCB) is a frequently detected groundwater contaminant which is toxic and was thought to be persistent under anoxic conditions. Furthermore, to date, no degradation pathways for anoxic MCB removal have been proven in the field. Hence, it is important to investigate MCB biodegradation in the environment, as groundwater is an important drinking water source in many European countries. Therefore, two pilot-scale horizontal subsurface-flow constructed wetlands, planted and unplanted, were used to investigate the processes in situ contributing to the biotransformation of MCB in these gradient systems. The wetlands were fed with anoxic MCB-contaminated groundwater from a nearby aquifer in Bitterfeld, Germany. An overall MCB removal was observed in both wetlands, whereas just 10% of the original MCB inflow concentration was detected in the ponds. In particular in the gravel bed of the planted wetland, MCB removal was highest in summer season with 73 ± 9% compared to the unplanted one with 40 ± 5%. Whereas the MCB concentrations rapidly decreased in the transition zone of unplanted gravel to the pond, a significant MCB removal was already determined in the anoxic gravel bed of the planted system. The investigation of hydro-geochemical parameters revealed that iron and sulphate reduction were relevant redox processes in both wetlands. In parallel, the addition of ferric iron or nitrate stimulated the mineralisation of MCB in laboratory microcosms with anoxic groundwater from the same source, indicating that the potential for anaerobic microbial degradation of MCB is present at the field site. - Highlights: • MCB removal in anoxic gravel bed of a planted and an unplanted constructed wetland was accompanied by iron

  15. Benchmarking Glucose Results through Automation: The 2009 Remote Automated Laboratory System Report

    Science.gov (United States)

    Anderson, Marcy; Zito, Denise; Kongable, Gail

    2010-01-01

    Background Hyperglycemia in the adult inpatient population remains a topic of intense study in U.S. hospitals. Most hospitals have established glycemic control programs but are unable to determine their impact. The 2009 Remote Automated Laboratory System (RALS) Report provides trends in glycemic control over 4 years to 576 U.S. hospitals to support their effort to manage inpatient hyperglycemia. Methods A proprietary software application feeds de-identified patient point-of-care blood glucose (POC-BG) data from the Medical Automation Systems RALS-Plus data management system to a central server. Analyses include the number of tests and the mean and median BG results for intensive care unit (ICU), non-ICU, and each hospital compared to the aggregate of the other hospitals. Results More than 175 million BG results were extracted from 2006–2009; 25% were from the ICU. Mean range of BG results for all inpatients in 2006, 2007, 2008, and 2009 was 142.2–201.9, 145.6–201.2, 140.6–205.7, and 140.7–202.4 mg/dl, respectively. The range for ICU patients was 128–226.5, 119.5–219.8, 121.6–226.0, and 121.1–217 mg/dl, respectively. The range for non-ICU patients was 143.4–195.5, 148.6–199.8, 145.2–201.9, and 140.7–203.6 mg/dl, respectively. Hyperglycemia rates of >180 mg/dl in 2008 and 2009 were examined, and hypoglycemia rates of Automated POC-BG data management software can assist in this effort. PMID:21129348

  16. An Overview of the Mars Science Laboratory Sample Acquisition, Sample Processing and Handling System

    Science.gov (United States)

    Beegle, L. W.; Anderson, R. C.; Hurowitz, J. A.; Jandura, L.; Limonadi, D.

    2012-12-01

    The Mars Science Laboratory Mission (MSL), landed on Mars on August 5. The rover and a scientific payload are designed to identify and assess the habitability, geological, and environmental histories of Gale crater. Unraveling the geologic history of the region and providing an assessment of present and past habitability requires an evaluation of the physical and chemical characteristics of the landing site; this includes providing an in-depth examination of the chemical and physical properties of Martian regolith and rocks. The MSL Sample Acquisition, Processing, and Handling (SA/SPaH) subsystem is the first in-situ system designed to acquire interior rock and soil samples from Martian surface materials. These samples are processed and separated into fine particles and distributed to two onboard analytical science instruments SAM (Sample Analysis at Mars Instrument Suite) and CheMin (Chemistry and Mineralogy) or to a sample analysis tray for visual inspection. The SA/SPaH subsystem is also responsible for the placement of the two contact instruments, Alpha Particle X-Ray Spectrometer (APXS), and the Mars Hand Lens Imager (MAHLI), on rock and soil targets. Finally, there is a Dust Removal Tool (DRT) to remove dust particles from rock surfaces for subsequent analysis by the contact and or mast mounted instruments (e.g. Mast Cameras (MastCam) and the Chemistry and Micro-Imaging instruments (ChemCam)). It is expected that the SA/SPaH system will have produced a scooped system and possibility a drilled sample in the first 90 sols of the mission. Results from these activities and the ongoing testing program will be presented.

  17. An Overview of the Naval Research Laboratory Ocean Surface Flux (NFLUX) System

    Science.gov (United States)

    May, J. C.; Rowley, C. D.; Barron, C. N.

    2016-02-01

    The Naval Research Laboratory (NRL) ocean surface flux (NFLUX) system is an end-to-end data processing and assimilation system used to provide near-real time satellite-based surface heat flux fields over the global ocean. Swath-level air temperature (TA), specific humidity (QA), and wind speed (WS) estimates are produced using multiple polynomial regression algorithms with inputs from satellite sensor data records from the Special Sensor Microwave Imager/Sounder, the Advanced Microwave Sounding Unit-A, the Advanced Technology Microwave Sounder, and the Advanced Microwave Scanning Radiometer-2 sensors. Swath-level WS estimates are also retrieved from satellite environmental data records from WindSat, the MetOp scatterometers, and the Oceansat scatterometer. Swath-level solar and longwave radiative flux estimates are produced utilizing the Rapid Radiative Transfer Model for Global Circulation Models (RRTMG). Primary inputs to the RRTMG include temperature and moisture profiles and cloud liquid and ice water paths from the Microwave Integrated Retrieval System. All swath-level satellite estimates undergo an automated quality control process and are then assimilated with atmospheric model forecasts to produce 3-hourly gridded analysis fields. The turbulent heat flux fields, latent and sensible heat flux, are determined from the Coupled Ocean-Atmosphere Response Experiment (COARE) 3.0 bulk algorithms using inputs of TA, QA, WS, and a sea surface temperature model field. Quality-controlled in situ observations over a one-year time period from May 2013 through April 2014 form the reference for validating ocean surface state parameter and heat flux fields. The NFLUX fields are evaluated alongside the Navy's operational global atmospheric model, the Navy Global Environmental Model (NAVGEM). NFLUX is shown to have smaller biases and lower or similar root mean square errors compared to NAVGEM.

  18. Integration of National Laboratory and Low-Activity Waste Pre-Treatment System Technology Service Providers - 16435

    Energy Technology Data Exchange (ETDEWEB)

    Subramanian, Karthik H.; Thien, Michael G.; Wellman, Dawn M.; Herman, Connie C.

    2017-03-08

    The National Laboratories are a critical partner and provide expertise in numerous aspects of the successful execution of the Direct-Feed Low Activity Waste Program. The National Laboratories are maturing the technologies of the Low-Activity Waste Pre-Treatment System (LAWPS) consistent with DOE Order 413.3B “Program and Project Management for the Acquisition of Capital Assets” expectations. The National Laboratories continue to mature waste forms, i.e. glass and secondary waste grout, for formulations and predictions of long-term performance as inputs to performance assessments. The working processes with the National Laboratories have been developed in procurements, communications, and reporting to support the necessary delivery-based technology support. The relationship continues to evolve from planning and technology development to support of ongoing operations and integration of multiple highly coordinated facilities.

  19. A laboratory exposure system to study the effects of aging on super-micron aerosol particles

    Energy Technology Data Exchange (ETDEWEB)

    Santarpia, Joshua; Sanchez, Andres L.; Lucero, Gabriel Anthony; Servantes, Brandon Lee; Hubbard, Joshua Allen

    2014-02-01

    A laboratory system was constructed that allows the super-micron particles to be aged for long periods of time under conditions that can simulate a range of natural environments and conditions, including relative humidity, oxidizing chemicals, organics and simulated solar radiation. Two proof-of-concept experiments using a non-biological simulant for biological particles and a biological simulant demonstrate the utility of these types of aging experiments. Green Visolite®, which is often used as a tracer material for model validation experiments, does not degrade with exposure to simulated solar radiation, the actual biological material does. This would indicate that Visolite® should be a good tracer compound for mapping the extent of a biological release using fluorescence as an indicator, but that it should not be used to simulate the decay of a biological particle when exposed to sunlight. The decay in the fluorescence measured for B. thurengiensis is similar to what has been previously observed in outdoor environments.

  20. Climate systems modeling on massively parallel processing computers at Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Wehner, W.F.; Mirin, A.A.; Bolstad, J.H. [and others

    1996-09-01

    A comprehensive climate system model is under development at Lawrence Livermore National Laboratory. The basis for this model is a consistent coupling of multiple complex subsystem models, each describing a major component of the Earth`s climate. Among these are general circulation models of the atmosphere and ocean, a dynamic and thermodynamic sea ice model, and models of the chemical processes occurring in the air, sea water, and near-surface land. The computational resources necessary to carry out simulations at adequate spatial resolutions for durations of climatic time scales exceed those currently available. Distributed memory massively parallel processing (MPP) computers promise to affordably scale to the computational rates required by directing large numbers of relatively inexpensive processors onto a single problem. We have developed a suite of routines designed to exploit current generation MPP architectures via domain and functional decomposition strategies. These message passing techniques have been implemented in each of the component models and in their coupling interfaces. Production runs of the atmospheric and oceanic components performed on the National Environmental Supercomputing Center (NESC) Cray T3D are described.

  1. Interactions between anaerobic ammonium and sulfur-oxidizing bacteria in a laboratory scale model system.

    Science.gov (United States)

    Russ, Lina; Speth, Daan R; Jetten, Mike S M; Op den Camp, Huub J M; Kartal, Boran

    2014-11-01

    Fixed nitrogen is released by anaerobic ammonium oxidation (anammox) and/or denitrification from (marine) ecosystems. Nitrite, the terminal electron acceptor of the anammox process, occurs in nature at very low concentrations and is produced via (micro)aerobic oxidation of ammonium or nitrate reduction. The coupling of sulfide-dependent denitrification to anammox is particularly interesting because besides hydrogen, sulfide is the most important reductant at the chemocline of anoxic marine basins and is abundant within sediments. Although at μM concentrations, sulfide may be toxic and inhibiting anammox activity, a denitrifying microorganism could convert sulfide and nitrate at sufficiently high rates to allow anammox bacteria to stay active despite an influx of sulfide. To test this hypothesis, a laboratory scale model system containing a co-culture of anammox bacteria and the autotrophic denitrifier Sulfurimonas denitrificans DSM1251 was started. Complementary techniques revealed that the gammaproteobacterial Sedimenticola sp. took over the intended role of Su. denitrificans. A stable coculture of anammox bacteria and Sedimenticola sp. consumed sulfide, nitrate, ammonium and CO2 . Anammox bacteria contributed 65-75% to the nitrogen loss from the reactor. The cooperation between anammox and sulfide-dependent denitrification may play a significant role in environments where sulfur cycling is active and where actual sulfide concentrations stay below μM range. © 2014 Society for Applied Microbiology and John Wiley & Sons Ltd.

  2. MetaLIMS, a simple open-source laboratory information management system for small metagenomic labs.

    Science.gov (United States)

    Heinle, Cassie Elizabeth; Gaultier, Nicolas Paul Eugène; Miller, Dana; Purbojati, Rikky Wenang; Lauro, Federico M

    2017-06-01

    As the cost of sequencing continues to fall, smaller groups increasingly initiate and manage larger sequencing projects and take on the complexity of data storage for high volumes of samples. This has created a need for low-cost laboratory information management systems (LIMS) that contain flexible fields to accommodate the unique nature of individual labs. Many labs do not have a dedicated information technology position, so LIMS must also be easy to setup and maintain with minimal technical proficiency. MetaLIMS is a free and open-source web-based application available via GitHub. The focus of MetaLIMS is to store sample metadata prior to sequencing and analysis pipelines. Initially designed for environmental metagenomics labs, in addition to storing generic sample collection information and DNA/RNA processing information, the user can also add fields specific to the user's lab. MetaLIMS can also produce a basic sequencing submission form compatible with the proprietary Clarity LIMS system used by some sequencing facilities. To help ease the technical burden associated with web deployment, MetaLIMS options the use of commercial web hosting combined with MetaLIMS bash scripts for ease of setup. MetaLIMS overcomes key challenges common in LIMS by giving labs access to a low-cost and open-source tool that also has the flexibility to meet individual lab needs and an option for easy deployment. By making the web application open source and hosting it on GitHub, we hope to encourage the community to build upon MetaLIMS, making it more robust and tailored to the needs of more researchers.

  3. Iron oxides stimulate microbial monochlorobenzene in situ transformation in constructed wetlands and laboratory systems.

    Science.gov (United States)

    Schmidt, Marie; Wolfram, Diana; Birkigt, Jan; Ahlheim, Jörg; Paschke, Heidrun; Richnow, Hans-Hermann; Nijenhuis, Ivonne

    2014-02-15

    Natural wetlands are transition zones between anoxic ground and oxic surface water which may enhance the (bio)transformation potential for recalcitrant chloro-organic contaminants due to the unique geochemical conditions and gradients. Monochlorobenzene (MCB) is a frequently detected groundwater contaminant which is toxic and was thought to be persistent under anoxic conditions. Furthermore, to date, no degradation pathways for anoxic MCB removal have been proven in the field. Hence, it is important to investigate MCB biodegradation in the environment, as groundwater is an important drinking water source in many European countries. Therefore, two pilot-scale horizontal subsurface-flow constructed wetlands, planted and unplanted, were used to investigate the processes in situ contributing to the biotransformation of MCB in these gradient systems. The wetlands were fed with anoxic MCB-contaminated groundwater from a nearby aquifer in Bitterfeld, Germany. An overall MCB removal was observed in both wetlands, whereas just 10% of the original MCB inflow concentration was detected in the ponds. In particular in the gravel bed of the planted wetland, MCB removal was highest in summer season with 73 ± 9% compared to the unplanted one with 40 ± 5%. Whereas the MCB concentrations rapidly decreased in the transition zone of unplanted gravel to the pond, a significant MCB removal was already determined in the anoxic gravel bed of the planted system. The investigation of hydro-geochemical parameters revealed that iron and sulphate reduction were relevant redox processes in both wetlands. In parallel, the addition of ferric iron or nitrate stimulated the mineralisation of MCB in laboratory microcosms with anoxic groundwater from the same source, indicating that the potential for anaerobic microbial degradation of MCB is present at the field site. Copyright © 2013 Elsevier B.V. All rights reserved.

  4. Impacts onto Icy Bodies: A Journey from the Laboratory to the Outer Solar System

    Science.gov (United States)

    Stewart, Sarah T.

    2009-09-01

    Impact craters on icy bodies display a wide range of morphologies, some of which have no counterpart on dry rocky bodies. The unique features include a variety of fluidized ejecta forms and crater floor structures such as pits and domes. These morphological characteristics have been attributed to the subsurface distribution and thermal states of H2O. In addition, crater depth to diameter trends on the icy Galilean satellites are thought to reflect the presence of subsurface oceans. If the physics of cratering in H2O were well understood, then the observed features on icy bodies could be used to derive a wealth of information about the distribution of H2O and thermal structure of bodies in the solar system. I will summarize recent work on crater formation on Mars and icy satellites that rely upon the combination of laboratory experiments, numerical modeling, and observations. Shock wave experiments have provided fundamental information about the response of H2O to an impact event. Numerical models of the equation of state and the temperature-dependent rheology of ice have been improved to capture essential physics during crater formation. Recent simulations of crater formation produce features similar to those observed on Mars and icy satellites and provide constraints on subsurface properties. Much of what we see on icy bodies can be explained by following the phase changes. Ice is melted by very modest shock pressures. As a result, liquid water may be produced during impacts onto ice throughout the solar system. At lower shock pressures, ice does not melt but undergoes crystallographic changes between different solid phases. These phase changes affect the dynamics of crater formation and lead to observable features that are unique to H2O.

  5. The development and testing of a 2D laboratory seismic modelling system for heterogeneous structure investigations

    Science.gov (United States)

    Mo, Yike; Greenhalgh, Stewart A.; Robertsson, Johan O. A.; Karaman, Hakki

    2015-05-01

    Lateral velocity variations and low velocity near-surface layers can produce strong scattered and guided waves which interfere with reflections and lead to severe imaging problems in seismic exploration. In order to investigate these specific problems by laboratory seismic modelling, a simple 2D ultrasonic model facility has been recently assembled within the Wave Propagation Lab at ETH Zurich. The simulated geological structures are constructed from 2 mm thick metal and plastic sheets, cut and bonded together. The experiments entail the use of a piezoelectric source driven by a pulse amplifier at ultrasonic frequencies to generate Lamb waves in the plate, which are detected by piezoelectric receivers and recorded digitally on a National Instruments recording system, under LabVIEW software control. The 2D models employed were constructed in-house in full recognition of the similitude relations. The first heterogeneous model features a flat uniform low velocity near-surface layer and deeper dipping and flat interfaces separating different materials. The second model is comparable but also incorporates two rectangular shaped inserts, one of low velocity, the other of high velocity. The third model is identical to the second other than it has an irregular low velocity surface layer of variable thickness. Reflection as well as transmission experiments (crosshole & vertical seismic profiling) were performed on each model. The two dominant Lamb waves recorded are the fundamental symmetric mode (non-dispersive) and the fundamental antisymmetric (flexural) dispersive mode, the latter normally being absent when the source transducer is located on a model edge but dominant when it is on the flat planar surface of the plate. Experimental group and phase velocity dispersion curves were determined and plotted for both modes in a uniform aluminium plate. For the reflection seismic data, various processing techniques were applied, as far as pre-stack Kirchhoff migration. The

  6. T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory

    Directory of Open Access Journals (Sweden)

    Albion Tim

    2005-10-01

    Full Text Available Abstract Background Single Nucleotide Polymorphism (SNP genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produces large amounts of data that are difficult to process by hand. Laboratories not equipped with a Laboratory Information Management System (LIMS need tools to organize the data flow. Results We propose a package of Visual Basic programs focused on sample management and on the parsing of input and output TaqMan files. The code is written in Visual Basic, embedded in the Microsoft Office package, and it allows anyone to have access to those tools, without any programming skills and with basic computer requirements. Conclusion We have created useful tools focused on management of TaqMan genotyping data, a critical issue in genotyping laboratories whithout a more sophisticated and expensive system, such as a LIMS.

  7. T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory

    Science.gov (United States)

    Monnier, Stéphanie; Cox, David G; Albion, Tim; Canzian, Federico

    2005-01-01

    Background Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produces large amounts of data that are difficult to process by hand. Laboratories not equipped with a Laboratory Information Management System (LIMS) need tools to organize the data flow. Results We propose a package of Visual Basic programs focused on sample management and on the parsing of input and output TaqMan files. The code is written in Visual Basic, embedded in the Microsoft Office package, and it allows anyone to have access to those tools, without any programming skills and with basic computer requirements. Conclusion We have created useful tools focused on management of TaqMan genotyping data, a critical issue in genotyping laboratories whithout a more sophisticated and expensive system, such as a LIMS. PMID:16221298

  8. Integrated management system best practices in radioecological laboratories; Sistema de gestao integrado: melhores praticas para laboratorios radioecologicos

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Claudia Aparecida Zerbinatti de

    2010-07-01

    The research aims to study the best practices to support a conceptual proposal for IMS - Integrated Management System (quality, environment, safety and health) applicable to Radioecology laboratories. The research design is organized into the following steps: in a first step, it was developed the bibliographic and documentary research in IMS, survey and study of standards (QMS ISO 9000 (2005), ISO 9001 (2008), ISO 9004 (2000), EMS ISO 14001 (2004) and OHSMS OHSAS 18001 (2007) and OHSAS 18002 (2008)), identification and characterization of processes in Radioecology Laboratories and study of best practices methodology and benchmarking; in the second stage of the research it was developed a case study (qualitative research, with questionnaires via e-mail and interviews, when possible), preceded by a survey and selection of international and national radioecology laboratories and then these laboratories were contacted and some of them agreed to participate in this research; in the third stage of the research it was built the framework of best practices that showed results that could support the conceptual proposal for the IMS Radioecology Laboratory; the fourth and final stage of research consisted in the construction of the proposed conceptual framework of SGI for Radioecology Laboratory, being then achieved the initial objective of the research. (author)

  9. A practical tool for monitoring the performance of measuring systems in a laboratory network: report of an ACB Working Group.

    Science.gov (United States)

    Ayling, Pete; Hill, Robert; Jassam, Nuthar; Kallner, Anders; Khatami, Zahra

    2017-11-01

    Background A logical consequence of the introduction of robotics and high-capacity analysers has seen a consolidation to larger units. This requires new structures and quality systems to ensure that laboratories deliver consistent and comparable results. Methods A spreadsheet program was designed to accommodate results from up to 12 different instruments/laboratories and present IQC data, i.e. Levey-Jennings and Youden plots and comprehensive numerical tables of the performance of each item. Input of data was made possible by a 'data loader' by which IQC data from the individual instruments could be transferred to the spreadsheet program on line. Results A set of real data from laboratories is used to populate the data loader and the networking software program. Examples are present from the analysis of variance components, the Levey-Jennings and Youden plots. Conclusions This report presents a software package that allows the simultaneous management and detailed monitoring of the performance of up to 12 different instruments/laboratories in a fully interactive mode. The system allows a quality manager of networked laboratories to have a continuous updated overview of the performance. This software package has been made available at the ACB website.

  10. A pulsed nanosecond IR laser diode system to automatically test the Single Event Effects in the laboratory

    CERN Document Server

    Alpat, B; Bizzarri, M; Blasko, S; Caraffini, D; Dimasso, L; Esposito, G; Farnesini, L; Ionica, M; Menichelli, M; Papi, A; Pontetti, G; Postolache, V

    2002-01-01

    A pulsed nanosecond IR laser diode system to automatically test the Single Event Effects in laboratory is described. The results of Single Event Latchup (SEL) test on two VLSI chips (VA sub H DR64, 0.8 and 1.2 mu m technology) are discussed and compared to those obtained with high-energy heavy ions at GSI (Darmstadt).

  11. Setting up a Low-Cost Lab Management System for a Multi-Purpose Computing Laboratory Using Virtualisation Technology

    Science.gov (United States)

    Mok, Heng Ngee; Lee, Yeow Leong; Tan, Wee Kiat

    2012-01-01

    This paper describes how a generic computer laboratory equipped with 52 workstations is set up for teaching IT-related courses and other general purpose usage. The authors have successfully constructed a lab management system based on decentralised, client-side software virtualisation technology using Linux and free software tools from VMware that…

  12. A Low-Cost Computer-Controlled Arduino-Based Educational Laboratory System for Teaching the Fundamentals of Photovoltaic Cells

    Science.gov (United States)

    Zachariadou, K.; Yiasemides, K.; Trougkakos, N.

    2012-01-01

    We present a low-cost, fully computer-controlled, Arduino-based, educational laboratory (SolarInsight) to be used in undergraduate university courses concerned with electrical engineering and physics. The major goal of the system is to provide students with the necessary instrumentation, software tools and methodology in order to learn fundamental…

  13. An Interactive Computer-Aided Instructional Strategy and Assessment Methods for System Identification and Adaptive Control Laboratory

    Science.gov (United States)

    Özbek, Necdet Sinan; Eker, Ilyas

    2015-01-01

    This study describes a set of real-time interactive experiments that address system identification and model reference adaptive control (MRAC) techniques. In constructing laboratory experiments that contribute to efficient teaching, experimental design and instructional strategy are crucial, but a process for doing this has yet to be defined. This…

  14. Plasma contactor modeling with NASCAP/LEO - Extending laboratory results to space systems

    Science.gov (United States)

    Davis, V. A.; Katz, I.; Mandell, M. J.

    1990-01-01

    In the laboratory, hollow cathode-based plasma contactors have been observed to both emit and collect ampere-level electron currents with low impedance. The laboratory behavior of hollow cathode-based plasma contactors and the limited space experience with hollow cathodes suggest that, for many applications, a hollow cathode-based plasma contactor is the ideal device to provide electrical connection with the space plasma. In order to confidently extend the laboratory experience to the low-earth-orbit environment, a series of plasma contactor computer models has been developed. Calculations show that a hollow cathode plasma contactor that collects 0.5 A in the laboratory will only collect 2.4 mA in space. The simplest way to boost the collected current is to increase the gas flow. A mole of gas is enough to collect ampere level currents for 5-1/2 hours.

  15. Piloting laboratory quality system management in six health facilities in Nigeria.

    Directory of Open Access Journals (Sweden)

    Henry Mbah

    Full Text Available Achieving accreditation in laboratories is a challenge in Nigeria like in most African countries. Nigeria adopted the World Health Organization Regional Office for Africa Stepwise Laboratory (Quality Improvement Process Towards Accreditation (WHO/AFRO- SLIPTA in 2010. We report on FHI360 effort and progress in piloting WHO-AFRO recognition and accreditation preparedness in six health facility laboratories in five different states of Nigeria.Laboratory assessments were conducted at baseline, follow up and exit using the WHO/AFRO- SLIPTA checklist. From the total percentage score obtained, the quality status of laboratories were classified using a zero to five star rating, based on the WHO/AFRO quality improvement stepwise approach. Major interventions include advocacy, capacity building, mentorship and quality improvement projects.At baseline audit, two of the laboratories attained 1- star while the remaining four were at 0- star. At follow up audit one lab was at 1- star, two at 3-star and three at 4-star. At exit audit, four labs were at 4- star, one at 3-star and one at 2-star rating. One laboratory dropped a 'star' at exit audit, while others consistently improved. The two weakest elements at baseline; internal audit (4% and occurrence/incidence management (15% improved significantly, with an exit score of 76% and 81% respectively. The elements facility and safety was the major strength across board throughout the audit exercise.This effort resulted in measurable and positive impact on the laboratories. We recommend further improvement towards a formal international accreditation status and scale up of WHO/AFRO- SLIPTA implementation in Nigeria.

  16. Evaluating a technology supported interactive response system during the laboratory section of a histology course.

    Science.gov (United States)

    Rinaldi, Vera D; Lorr, Nancy A; Williams, Kimberly

    2017-07-01

    Monitoring of student learning through systematic formative assessment is important for adjusting pedagogical strategies. However, traditional formative assessments, such as quizzes and written assignments, may not be sufficiently timely for making adjustments to a learning process. Technology supported formative assessment tools assess student knowledge, allow for immediate feedback, facilitate classroom dialogues, and have the potential to modify student learning strategies. As an attempt to integrate technology supported formative assessment in the laboratory section of an upper-level histology course, the interactive application Learning CatalyticsTM , a cloud-based assessment system, was used. This study conducted during the 2015 Histology courses at Cornell University concluded that this application is helpful for identifying student misconceptions "on-the-go," engaging otherwise marginalized students, and forming a new communication venue between students and instructors. There was no overall difference between grades from topics that used the application and grades from those that did not, and students reported that it only slightly helped improve their understanding of the topic (3.8 ± 0.99 on a five-point Likert scale). However, they highly recommended using it (4.2 ± 0.71). The major limitation was regarding the image display and graphical resolution of this application. Even though students embrace the use of technology, 39% reported benefits of having the traditional light microscope available. This cohort of students led instructors to conclude that the newest tools are not always better, but rather can complement traditional instruction methods. Anat Sci Educ 10: 328-338. © 2016 American Association of Anatomists. © 2016 American Association of Anatomists.

  17. Validation Ice Crystal Icing Engine Test in the Propulsion Systems Laboratory at NASA Glenn Research Center

    Science.gov (United States)

    Oliver, Michael J.

    2014-01-01

    The Propulsion Systems Laboratory (PSL) is an existing altitude simulation jet engine test facility located at NASA Glenn Research Center in Cleveland, OH. It was modified in 2012 with the integration of an ice crystal cloud generation system. This paper documents the inaugural ice crystal cloud test in PSL--the first ever full scale, high altitude ice crystal cloud turbofan engine test to be conducted in a ground based facility. The test article was a Lycoming ALF502-R5 high bypass turbofan engine, serial number LF01. The objectives of the test were to validate the PSL ice crystal cloud calibration and engine testing methodologies by demonstrating the capability to calibrate and duplicate known flight test events that occurred on the same LF01 engine and to generate engine data to support fundamental and computational research to investigate and better understand the physics of ice crystal icing in a turbofan engine environment while duplicating known revenue service events and conducting test points while varying facility and engine parameters. During PSL calibration testing it was discovered than heated probes installed through tunnel sidewalls experienced ice buildup aft of their location due to ice crystals impinging upon them, melting and running back. Filtered city water was used in the cloud generation nozzle system to provide ice crystal nucleation sites. This resulted in mineralization forming on flow path hardware that led to a chronic degradation of performance during the month long test. Lacking internal flow path cameras, the response of thermocouples along the flow path was interpreted as ice building up. Using this interpretation, a strong correlation between total water content (TWC) and a weaker correlation between median volumetric diameter (MVD) of the ice crystal cloud and the rate of ice buildup along the instrumented flow path was identified. For this test article the engine anti-ice system was required to be turned on before ice crystal

  18. User Guide: How to Use and Operate Virtual Reality Equipment in the Systems Assessment and Usability Laboratory (SAUL) for Conducting Demonstrations

    Science.gov (United States)

    2017-08-01

    ARL-TN-0839 ● AUG 2017 US Army Research Laboratory User Guide: How to Use and Operate Virtual Reality Equipment in the Systems...ARL-TN-0839 ● AUG 2017 US Army Research Laboratory User Guide: How to Use and Operate Virtual Reality Equipment in the Systems...September 2017 4. TITLE AND SUBTITLE User Guide: How to Use and Operate Virtual Reality Equipment in the Systems Assessment and Usability Laboratory

  19. Effectiveness of a computerized alert system based on re-testing intervals for limiting the inappropriateness of laboratory test requests.

    Science.gov (United States)

    Lippi, Giuseppe; Brambilla, Marco; Bonelli, Patrizia; Aloe, Rosalia; Balestrino, Antonio; Nardelli, Anna; Ceda, Gian Paolo; Fabi, Massimo

    2015-11-01

    There is consolidated evidence that the burden of inappropriate laboratory test requests is very high, up to 70%. We describe here the function of a computerized alert system linked to the order entry, designed to limit the number of potentially inappropriate laboratory test requests. A computerized alert system based on re-testing intervals and entailing the generation of pop-up alerts when preset criteria of appropriateness for 15 laboratory tests were violated was implemented in two clinical wards of the University Hospital of Parma. The effectiveness of the system for limiting potentially inappropriate tests was monitored for 6months. Overall, 765/3539 (22%) test requests violated the preset criteria of appropriateness and generated the appearance of electronic alert. After alert appearance, 591 requests were annulled (17% of total tests requested and 77% of tests alerted, respectively). The total number of test requests violating the preset criteria of inappropriateness constantly decreased over time (26% in the first three months of implementation versus 17% in the following period; prequests, generating significant economic saving and educating physicians to a more efficient use of laboratory resources. Copyright © 2015 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

  20. Essential attributes identified in the design of a Laboratory Information Management System for a high throughput siRNA screening laboratory.

    Science.gov (United States)

    Grandjean, Geoffrey; Graham, Ryan; Bartholomeusz, Geoffrey

    2011-11-01

    In recent years high throughput screening operations have become a critical application in functional and translational research. Although a seemingly unmanageable amount of data is generated by these high-throughput, large-scale techniques, through careful planning, an effective Laboratory Information Management System (LIMS) can be developed and implemented in order to streamline all phases of a workflow. Just as important as data mining and analysis procedures at the end of complex processes is the tracking of individual steps of applications that generate such data. Ultimately, the use of a customized LIMS will enable users to extract meaningful results from large datasets while trusting the robustness of their assays. To illustrate the design of a custom LIMS, this practical example is provided to highlight the important aspects of the design of a LIMS to effectively modulate all aspects of an siRNA screening service. This system incorporates inventory management, control of workflow, data handling and interaction with investigators, statisticians and administrators. All these modules are regulated in a synchronous manner within the LIMS. © 2011 Bentham Science Publishers

  1. Real-Time Rocket/Vehicle System Integrated Health Management Laboratory For Development and Testing of Health Monitoring/Management Systems

    Science.gov (United States)

    Aguilar, R.

    2006-01-01

    Pratt & Whitney Rocketdyne has developed a real-time engine/vehicle system integrated health management laboratory, or testbed, for developing and testing health management system concepts. This laboratory simulates components of an integrated system such as the rocket engine, rocket engine controller, vehicle or test controller, as well as a health management computer on separate general purpose computers. These general purpose computers can be replaced with more realistic components such as actual electronic controllers and valve actuators for hardware-in-the-loop simulation. Various engine configurations and propellant combinations are available. Fault or failure insertion capability on-the-fly using direct memory insertion from a user console is used to test system detection and response. The laboratory is currently capable of simulating the flow-path of a single rocket engine but work is underway to include structural and multiengine simulation capability as well as a dedicated data acquisition system. The ultimate goal is to simulate as accurately and realistically as possible the environment in which the health management system will operate including noise, dynamic response of the engine/engine controller, sensor time delays, and asynchronous operation of the various components. The rationale for the laboratory is also discussed including limited alternatives for demonstrating the effectiveness and safety of a flight system.

  2. The Application of System Dynamics to the Integration of National Laboratory Research and K-12 Education

    Energy Technology Data Exchange (ETDEWEB)

    Mills, James Ignatius; Zounar Harbour, Elda D

    2001-08-01

    The Idaho National Engineering and Environmental Laboratory (INEEL) is dedicated to finding solutions to problems related to the environment, energy, economic competitiveness, and national security. In an effort to attract and retain the expertise needed to accomplish these challenges, the INEEL is developing a program of broad educational opportunities that makes continuing education readily available to all laboratory employees, beginning in the K–12 environment and progressing through post-graduate education and beyond. One of the most innovative educational approaches being implemented at the laboratory is the application of STELLA© dynamic learning environments, which facilitate captivating K–12 introductions to the complex energy and environmental challenges faced by global societies. These simulations are integrated into lesson plans developed by teachers in collaboration with INEEL scientists and engineers. This approach results in an enjoyable and involved learning experience, and an especially positive introduction to the application of science to emerging problems of great social and environmental consequence.

  3. PathOS: a decision support system for reporting high throughput sequencing of cancers in clinical diagnostic laboratories.

    Science.gov (United States)

    Doig, Kenneth D; Fellowes, Andrew; Bell, Anthony H; Seleznev, Andrei; Ma, David; Ellul, Jason; Li, Jason; Doyle, Maria A; Thompson, Ella R; Kumar, Amit; Lara, Luis; Vedururu, Ravikiran; Reid, Gareth; Conway, Thomas; Papenfuss, Anthony T; Fox, Stephen B

    2017-04-24

    The increasing affordability of DNA sequencing has allowed it to be widely deployed in pathology laboratories. However, this has exposed many issues with the analysis and reporting of variants for clinical diagnostic use. Implementing a high-throughput sequencing (NGS) clinical reporting system requires a diverse combination of capabilities, statistical methods to identify variants, global variant databases, a validated bioinformatics pipeline, an auditable laboratory workflow, reproducible clinical assays and quality control monitoring throughout. These capabilities must be packaged in software that integrates the disparate components into a useable system. To meet these needs, we developed a web-based application, PathOS, which takes variant data from a patient sample through to a clinical report. PathOS has been used operationally in the Peter MacCallum Cancer Centre for two years for the analysis, curation and reporting of genetic tests for cancer patients, as well as the curation of large-scale research studies. PathOS has also been deployed in cloud environments allowing multiple institutions to use separate, secure and customisable instances of the system. Increasingly, the bottleneck of variant curation is limiting the adoption of clinical sequencing for molecular diagnostics. PathOS is focused on providing clinical variant curators and pathology laboratories with a decision support system needed for personalised medicine. While the genesis of PathOS has been within cancer molecular diagnostics, the system is applicable to NGS clinical reporting generally. The widespread availability of genomic sequencers has highlighted the limited availability of software to support clinical decision-making in molecular pathology. PathOS is a system that has been developed and refined in a hospital laboratory context to meet the needs of clinical diagnostics. The software is available as a set of Docker images and source code at https://github.com/PapenfussLab/PathOS .

  4. Laboratorial training of examiners for using a visual caries detection system in epidemiological surveys.

    Science.gov (United States)

    Piovesan, Chaiana; Moro, Bruna Lp; Lara, Juan S; Ardenghi, Thiago M; Guedes, Renata S; Haddad, Ana E; Braga, Mariana M; Mendes, Fausto M

    2013-10-03

    In epidemiological surveys, a good reliability among the examiners regarding the caries detection method is essential. However, training and calibrating those examiners is an arduous task because it involves several patients who are examined many times. To facilitate this step, we aimed to propose a laboratory methodology to simulate the examinations performed to detect caries lesions using the International Caries Detection and Assessment System (ICDAS) in epidemiological surveys. A benchmark examiner conducted all training sessions. A total of 67 exfoliated primary teeth, varying from sound to extensive cavitated, were set in seven arch models to simulate complete mouths in primary dentition. Sixteen examiners (graduate students) evaluated all surfaces of the teeth under illumination using buccal mirrors and ball-ended probe in two occasions, using only coronal primary caries scores of the ICDAS. As reference standard, two different examiners assessed the proximal surfaces by direct visual inspection, classifying them in sound, with non-cavitated or with cavitated lesions. After, teeth were sectioned in the bucco-lingual direction, and the examiners assessed the sections in stereomicroscope, classifying the occlusal and smooth surfaces according to lesion depth. Inter-examiner reproducibility was evaluated using weighted kappa. Sensitivities and specificities were calculated at two thresholds: all lesions and advanced lesions (cavitated lesions in proximal surfaces and lesions reaching the dentine in occlusal and smooth surfaces). Regarding the reproducibility, the mean (range) of kappa values was 0.781 (0.529-0.927) for occlusal surfaces, 0.568 (0.191-0.881) for smooth surfaces, and 0.844 (0.698-0.971) for proximal surfaces. Considering all lesions, sensitivity and specificity mean values were respectively 0.724 and 0.844 for occlusal, 0.635 and 0.943 for smooth and 0.658 and 0.927 for proximal surfaces. For detecting advanced lesions, sensitivities and

  5. Development of a speech-based dialogue system for report dictation and machine control in the endoscopic laboratory.

    Science.gov (United States)

    Molnar, B; Gergely, J; Toth, G; Pronai, L; Zagoni, T; Papik, K; Tulassay, Z

    2000-01-01

    Reporting and machine control based on speech technology can enhance work efficiency in the gastrointestinal endoscopy laboratory. The status and activation of endoscopy laboratory equipment were described as a multivariate parameter and function system. Speech recognition, text evaluation and action definition engines were installed. Special programs were developed for the grammatical analysis of command sentences, and a rule-based expert system for the definition of machine answers. A speech backup engine provides feedback to the user. Techniques were applied based on the "Hidden Markov" model of discrete word, user-independent speech recognition and on phoneme-based speech synthesis. Speech samples were collected from three male low-tone investigators. The dictation module and machine control modules were incorporated in a personal computer (PC) simulation program. Altogether 100 unidentified patient records were analyzed. The sentences were grouped according to keywords, which indicate the main topics of a gastrointestinal endoscopy report. They were: "endoscope", "esophagus", "cardia", "fundus", "corpus", "antrum", "pylorus", "bulbus", and "postbulbar section", in addition to the major pathological findings: "erosion", "ulceration", and "malignancy". "Biopsy" and "diagnosis" were also included. We implemented wireless speech communication control commands for equipment including an endoscopy unit, video, monitor, printer, and PC. The recognition rate was 95%. Speech technology may soon become an integrated part of our daily routine in the endoscopy laboratory. A central speech and laboratory computer could be the most efficient alternative to having separate speech recognition units in all items of equipment.

  6. A new approach to laboratory information management systems; Uma nova abordagem para sistemas de gerenciamento de informacoes laboratoriais

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Felipe dos Santos; Cardoso, Denise Lopes; Rubiao, Luiz Eduardo G. [Chemtech Servicos de Engenharia e Software Ltda., Rio de Janeiro, RJ (Brazil); Jacinto, Marcos [Ipiranga Petroquimica S.A., Triunfo, RS (Brazil)

    2000-07-01

    The use of Laboratory Information Management System (LIMS) tools to increase products and services quality has been constantly increasing in laboratories all over the world. In the industrial segment, the research and quality control laboratories look forward, through a LIMS solution, not only a tool for increasing the production and efficiency of the LAB team, but also to delivery the results to their clients in an efficient and quick way, reducing the report and certificate delivery time. As in all other information system, the Internet Technology has been improving the LIMS functionalities. The products current available on the global market tend to migrate their conventional architecture based on proprietary tools to an open architecture, portable and accessible all over the world wide web. After two implementations of web based LIMS in Brazil (at the quality control and research laboratories of Deten Quimica S/A, Camacari - BA and Ipiranga Petroquimica S/A, Triunfo - RS, Brazil), it was observed the improvement of the LAB team performance, the reduction of the results delivery time to the final clients and the effective integration of the LAB team with other corporation groups. (author)

  7. HYDROMECHANICS LABORATORY

    Data.gov (United States)

    Federal Laboratory Consortium — Naval Academy Hydromechanics LaboratoryThe Naval Academy Hydromechanics Laboratory (NAHL) began operations in Rickover Hall in September 1976. The primary purpose of...

  8. Bioassay Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Bioassay Laboratory is an accredited laboratory capable of conducting standardized and innovative environmental testing in the area of aquatic ecotoxicology. The...

  9. Laboratory Evaluation of the Toxicity of Systemic Insecticides to Emerald Ash Borer Larvae

    Science.gov (United States)

    Therese M. Poland; Tina M. Ciaramitaro; Deborah G. McCullough

    2015-01-01

    Emerald ash borer (Agrilus planipennis Fairmaire) (Coleoptera: Buprestidae), an invasive phloem-feeding insect native to Asia, threatens at least 16 North American ash (Fraxinus) species and has killed hundreds of millions of ash trees in landscapes and forests. We conducted laboratory bioassays to assess the relative efficacy...

  10. An Easy-to-Build Remote Laboratory with Data Transfer Using the Internet School Experimental System

    Science.gov (United States)

    Schauer, Frantisek; Lustig, Frantisek; Dvorak, Jiri; Ozvoldova, Miroslava

    2008-01-01

    The present state of information communication technology makes it possible to devise and run computer-based e-laboratories accessible to any user with a connection to the Internet, equipped with very simple technical means and making full use of web services. Thus, the way is open for a new strategy of physics education with strongly global…

  11. Low-level multicounter {beta}/{gamma} systems with external guards in surface and shallow underground laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Theodorsson, P. [Iceland Univ. (Iceland). Science Inst.

    1997-03-01

    When weak samples are measured it is important that they can be given ample counting time in order to obtain satisfactory accuracy and that the background count rate can be checked well. This calls for a high counting capacity, which multidetectors can bring us. I will discuss development possibilities of low-level {beta}/{gamma} multidetector systems with an external anticosmic shield that will in many cases be operated in underground laboratories. These simple and low-cost system can frequently help us in increasing the number of detectors. Three concepts are combined in these systems: (1) multidetectors, (2) an external anticosmic (or guard) detector arrangement and (3) overburden shielding. (orig.)

  12. A web-based laboratory information system to improve quality of care of tuberculosis patients in Peru: functional requirements, implementation and usage statistics

    OpenAIRE

    Yale Gloria; Yagui Martin JA; Shin Sonya S; Blaya Joaquin A; Suarez Carmen Z; Asencios Luis L; Cegielski J Peter; Fraser Hamish SF

    2007-01-01

    Abstract Background Multi-drug resistant tuberculosis patients in resource-poor settings experience large delays in starting appropriate treatment and may not be monitored appropriately due to an overburdened laboratory system, delays in communication of results, and missing or error-prone laboratory data. The objective of this paper is to describe an electronic laboratory information system implemented to alleviate these problems and its expanding use by the Peruvian public sector, as well a...

  13. Development of an Excel-based laboratory information management system for improving workflow efficiencies in early ADME screening.

    Science.gov (United States)

    Lu, Xinyan

    2016-01-01

    There is a clear requirement for enhancing laboratory information management during early absorption, distribution, metabolism and excretion (ADME) screening. The application of a commercial laboratory information management system (LIMS) is limited by complexity, insufficient flexibility, high costs and extended timelines. An improved custom in-house LIMS for ADME screening was developed using Excel. All Excel templates were generated through macros and formulae, and information flow was streamlined as much as possible. This system has been successfully applied in task generation, process control and data management, with a reduction in both labor time and human error rates. An Excel-based LIMS can provide a simple, flexible and cost/time-saving solution for improving workflow efficiencies in early ADME screening.

  14. A virtual laboratory for the simulation of sustainable energy systems in a low energy building: A case study

    Science.gov (United States)

    Breen, M.; O'Donovan, A.; Murphy, M. D.; Delaney, F.; Hill, M.; Sullivan, P. D. O.

    2016-03-01

    The aim of this paper was to develop a virtual laboratory simulation platform of the National Building Retrofit Test-bed at the Cork Institute of Technology, Ireland. The building in question is a low-energy retrofit which is provided with electricity by renewable systems including photovoltaics and wind. It can be thought of as a living laboratory, as a number of internal and external building factors are recorded at regular intervals during human occupation. The analysis carried out in this paper demonstrated that, for the period from April to September 2015, the electricity provided by the renewable systems did not consistently match the building’s electricity requirements due to differing load profiles. It was concluded that the use of load shifting techniques may help to increase the percentage of renewable energy utilisation.

  15. Preferred Names, Preferred Pronouns, and Gender Identity in the Electronic Medical Record and Laboratory Information System: Is Pathology Ready?

    Science.gov (United States)

    Imborek, Katherine L; Nisly, Nicole L; Hesseltine, Michael J; Grienke, Jana; Zikmund, Todd A; Dreyer, Nicholas R; Blau, John L; Hightower, Maia; Humble, Robert M; Krasowski, Matthew D

    2017-01-01

    Electronic medical records (EMRs) and laboratory information systems (LISs) commonly utilize patient identifiers such as legal name, sex, medical record number, and date of birth. There have been recommendations from some EMR working groups (e.g., the World Professional Association for Transgender Health) to include preferred name, pronoun preference, assigned sex at birth, and gender identity in the EMR. These practices are currently uncommon in the United States. There has been little published on the potential impact of these changes on pathology and LISs. We review the available literature and guidelines on the use of preferred name and gender identity on pathology, including data on changes in laboratory testing following gender transition treatments. We also describe pathology and clinical laboratory challenges in the implementation of preferred name at our institution. Preferred name, pronoun preference, and gender identity have the most immediate impact on the areas of pathology with direct patient contact such as phlebotomy and transfusion medicine, both in terms of interaction with patients and policies for patient identification. Gender identity affects the regulation and policies within transfusion medicine including blood donor risk assessment and eligibility. There are limited studies on the impact of gender transition treatments on laboratory tests, but multiple studies have demonstrated complex changes in chemistry and hematology tests. A broader challenge is that, even as EMRs add functionality, pathology computer systems (e.g., LIS, middleware, reference laboratory, and outreach interfaces) may not have functionality to store or display preferred name and gender identity. Implementation of preferred name, pronoun preference, and gender identity presents multiple challenges and opportunities for pathology.

  16. Ice Crystal Icing Engine Testing in the NASA Glenn Research Center's Propulsion Systems Laboratory (PSL): Altitude Investigation

    Science.gov (United States)

    Oliver, Michael J.

    2015-01-01

    The National Aeronautics and Space Administration conducted a full scale ice crystal icing turbofan engine test in the NASA Glenn Research Centers Propulsion Systems Laboratory (PSL) Facility in February 2013. Honeywell Engines supplied the test article, an obsolete, unmodified Lycoming ALF502-R5 turbofan engine serial number LF01 that experienced an un-commanded loss of thrust event while operating at certain high altitude ice crystal icing conditions. These known conditions were duplicated in the PSL for this testing.

  17. Photochemical Activity of Aldrin and Dieldrin in Liquid and Frozen Aqueous Systems: Field and Laboratory Studies

    Science.gov (United States)

    Bausch, A. R.; Rowland, G. A.; Grannas, A. M.

    2008-12-01

    The phenomenon of global distillation generates significant accumulation of volatile, anthropogenic persistent organic pollutants (POPs) in polar regions. Bioaccumulation presents serious concerns for human health within Arctic subsistence communities. In the recent past, the photochemical processes of POPs have been observed in the laboratory. Despite some established knowledge regarding photochemical processes in reactive frozen media, little published literature exists regarding the chemical transformations and fate of POPs in the Arctic. Here, we consider the photochemical transformations of aldrin and dieldrin, two structurally similar organochlorine pollutants whose presence has been confirmed in the Arctic. Their photochemical transformation, resulting from ultraviolet exposure, was investigated by both field studies in Barrow, AK and controlled laboratory experiments. Pollutant degradation and photoproduct formation were monitored by GC-ECD analysis. Based on kinetic studies of liquid and frozen samples and identification of photoproducts, we will propose potential reaction mechanisms for the transformations of aldrin and dieldrin. Further implications for environmental processes will be discussed.

  18. Improvement of the military academy education system for aeronautics students using the flying laboratory

    Directory of Open Access Journals (Sweden)

    Slobodan N. Stupar

    2013-02-01

    Full Text Available Normal 0 false false false MicrosoftInternetExplorer4 This paper describes a proposal to improve the educational process of students of the Military Academy to support the maintenance process of the Serbian Army aircraft based on the introduction of objects in flight test aircraft. It is particularly emphasized the importance of establishing airline laboratories with basic characteristics of the test-measuring equipment that is necessary to integrate the aircraft to perform a practical test of an aircraft in flight. The formation of aircraft laboratories would form a very strong didactic tool, which provides for optimal synthesis of theory and practice. This concept of improving the educational process would be substantially affected the awareness of the necessity of working together and put together all the research capacity of scientific institutions in the Ministry of Defence of the Republic of Serbia.

  19. Piloting a national laboratory electronic programme status reporting system in Ekurhuleni health district, South Africa.

    Science.gov (United States)

    Cassim, N; Coetzee, L M; Glencross, D K

    2016-03-08

    The National Health Laboratory Service (NHLS) performs ~4 million CD4 tests per annum for the public health sector at 61 CD4 testing laboratories across South Africa. Currently, CD4 laboratory data captured do not differentiate between antiretroviral treatment (ART) and pre-ART care. A cross-sectional study was undertaken to evaluate a redesigned Comprehensive Care, Management and Treatment of HIV and AIDS (CCMT) request form, incorporating a two-tick collection procedure linking the CD4 test request to patient CCMT programme status. Field testing was undertaken at three health facilities, where healthcare personnel were required to capture whether the CD4 count requested was a 'first-ever CD4', 'CD4 taken previously, not yet in ART care' or 'in ART care'. All data were extracted from the NHLS Corporate Data Warehouse and analysed using Microsoft Excel and Stata-12. A substantial increase in the number of request forms with a CCMT programme status (28.1% v. 84.4%) was reported pre- and post-implementation. Post-implementation data (N=1 004) revealed that 30.8% patients were ART naive ('first-ever CD4'), with 7.4% 'not yet on ART' (median CD4 counts of 150 and 328 cells/µL, respectively). Patients on ART comprised 61.9% of the study group (median CD4 count ~346 cells/µL). Sixty percent of patients were aged between 30 and 44 years, and females predominated (male/female ratio 0.7:1). A simple modification to the CCMT request form can successfully facilitate collection of programme status. For national implementation, it would be advantageous to have a unique patient identifier to further enhance laboratory-based programmatic monitoring and evaluation.

  20. Modeling of a Turbofan Engine with Ice Crystal Ingestion in the NASA Propulsion System Laboratory

    Science.gov (United States)

    Veres, Joseph P.; Jorgenson, Philip C. E.; Jones, Scott M.; Nili, Samaun

    2017-01-01

    The main focus of this study is to apply a computational tool for the flow analysis of the turbine engine that has been tested with ice crystal ingestion in the Propulsion Systems Laboratory (PSL) at NASA Glenn Research Center. The PSL has been used to test a highly instrumented Honeywell ALF502R-5A (LF11) turbofan engine at simulated altitude operating conditions. Test data analysis with an engine cycle code and a compressor flow code was conducted to determine the values of key icing parameters, that can indicate the risk of ice accretion, which can lead to engine rollback (un-commanded loss of engine thrust). The full engine aerothermodynamic performance was modeled with the Honeywell Customer Deck specifically created for the ALF502R-5A engine. The mean-line compressor flow analysis code, which includes a code that models the state of the ice crystal, was used to model the air flow through the fan-core and low pressure compressor. The results of the compressor flow analyses included calculations of the ice-water flow rate to air flow rate ratio (IWAR), the local static wet bulb temperature, and the particle melt ratio throughout the flow field. It was found that the assumed particle size had a large effect on the particle melt ratio, and on the local wet bulb temperature. In this study the particle size was varied parametrically to produce a non-zero calculated melt ratio in the exit guide vane (EGV) region of the low pressure compressor (LPC) for the data points that experienced a growth of blockage there, and a subsequent engine called rollback (CRB). At data points where the engine experienced a CRB having the lowest wet bulb temperature of 492 degrees Rankine at the EGV trailing edge, the smallest particle size that produced a non-zero melt ratio (between 3 percent - 4 percent) was on the order of 1 micron. This value of melt ratio was utilized as the target for all other subsequent data points analyzed, while the particle size was varied from 1 micron - 9

  1. Cost Comparison in 2015 Dollars for Radioisotope Power Systems -- Cassini and Mars Science Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Werner, James Elmer [Idaho National Lab. (INL), Idaho Falls, ID (United States); Johnson, Stephen Guy [Idaho National Lab. (INL), Idaho Falls, ID (United States); Dwight, Carla Chelan [Idaho National Lab. (INL), Idaho Falls, ID (United States); Lively, Kelly Lynn [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-07-01

    Radioisotope power systems (RPSs) have enabled missions requiring reliable, long-lasting power in remote, harsh environments such as space since the early 1960s. Costs for RPSs are high, but are often misrepresented due to the complexity of space missions and inconsistent charging practices among the many and changing participant organizations over the years. This paper examines historical documentation associated with two past successful flight missions, each with a different RPS design, to provide a realistic cost basis for RPS production and deployment. The missions and their respective RPSs are Cassini, launched in 1997, that uses the general purpose heat source (GPHS) radioisotope thermoelectric generator (RTG), and Mars Science Laboratory (MSL), launched in 2011, that uses the multi-mission RTG (MMRTG). Actual costs in their respective years are discussed for each of the two RTG designs and the missions they enabled, and then present day values to 2015 are computed to compare the costs. Costs for this analysis were categorized into two areas: development of the specific RTG technology, and production and deployment of an RTG. This latter category includes material costs for the flight components (including Pu-238 and fine weave pierced fabric (FWPF)); manufacturing of flight components; assembly, testing, and transport of the flight RTG(s); ground operations involving the RTG(s) through launch; nuclear safety analyses for the launch and for the facilities housing the RTG(s) during all phases of ground operations; DOE’s support for NEPA analyses; and radiological contingency planning. This analysis results in a fairly similar 2015 normalized cost for the production and deployment of an RTG—approximately $118M for the GPHS-RTG and $109M for the MMRTG. In addition to these two successful flight missions, the costs for development of the MMRTG are included to serve as a future reference. Note that development costs included herein for the MMRTG do not include

  2. Optimization of the Promega PowerSeq™ Auto/Y system for efficient integration within a forensic DNA laboratory.

    Science.gov (United States)

    Montano, E A; Bush, J M; Garver, A M; Larijani, M M; Wiechman, S M; Baker, C H; Wilson, M R; Guerrieri, R A; Benzinger, E A; Gehres, D N; Dickens, M L

    2018-01-01

    The application of massively parallel sequencing (MPS) is growing in the forensic DNA field, as forensic DNA laboratories are continuously seeking methods to gain information from a limited or degraded forensic sample. However, the laborious nature of current MPS methodologies required for successful library preparation and sequencing leave opportunities for improvement to make MPS a practical option for processing forensic casework. In this study, the Promega PowerSeq™ Auto/Y System Prototype, a MPS laboratory workflow that incorporates multiplex amplification, was selected for optimization with the objectives to introduce automation for relieving manual processing, and to reduce the number of steps recommended by the standard protocol. Successful changes in the optimized workflow included a switch from column-based PCR purification to automatable bead-based purification, adoption of the library preparation procedures by a liquid handling robot platform, and removal of various time-consuming quality checks. All data in this study were found to be concordant with capillary electrophoresis (CE) data and previously-generated MPS results from this workflow. Read abundance and allele balance, metrics related to sample interpretation reliability, were not significantly different when compared to samples processed with the manufacturer's protocol. All the modifications implemented resulted in increased laboratory efficiency, reduced the protocol steps associated with risk of contamination and human error events, and decreased manual processing time by approximately 12h. These findings provide forensic DNA laboratories a more streamlined option when considering implementation of a MPS workflow. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. An automated image analysis system to measure and count organisms in laboratory microcosms.

    Directory of Open Access Journals (Sweden)

    François Mallard

    Full Text Available 1. Because of recent technological improvements in the way computer and digital camera perform, the potential use of imaging for contributing to the study of communities, populations or individuals in laboratory microcosms has risen enormously. However its limited use is due to difficulties in the automation of image analysis. 2. We present an accurate and flexible method of image analysis for detecting, counting and measuring moving particles on a fixed but heterogeneous substrate. This method has been specifically designed to follow individuals, or entire populations, in experimental laboratory microcosms. It can be used in other applications. 3. The method consists in comparing multiple pictures of the same experimental microcosm in order to generate an image of the fixed background. This background is then used to extract, measure and count the moving organisms, leaving out the fixed background and the motionless or dead individuals. 4. We provide different examples (springtails, ants, nematodes, daphnia to show that this non intrusive method is efficient at detecting organisms under a wide variety of conditions even on faintly contrasted and heterogeneous substrates. 5. The repeatability and reliability of this method has been assessed using experimental populations of the Collembola Folsomia candida. 6. We present an ImageJ plugin to automate the analysis of digital pictures of laboratory microcosms. The plugin automates the successive steps of the analysis and recursively analyses multiple sets of images, rapidly producing measurements from a large number of replicated microcosms.

  4. An automated image analysis system to measure and count organisms in laboratory microcosms.

    Science.gov (United States)

    Mallard, François; Le Bourlot, Vincent; Tully, Thomas

    2013-01-01

    1. Because of recent technological improvements in the way computer and digital camera perform, the potential use of imaging for contributing to the study of communities, populations or individuals in laboratory microcosms has risen enormously. However its limited use is due to difficulties in the automation of image analysis. 2. We present an accurate and flexible method of image analysis for detecting, counting and measuring moving particles on a fixed but heterogeneous substrate. This method has been specifically designed to follow individuals, or entire populations, in experimental laboratory microcosms. It can be used in other applications. 3. The method consists in comparing multiple pictures of the same experimental microcosm in order to generate an image of the fixed background. This background is then used to extract, measure and count the moving organisms, leaving out the fixed background and the motionless or dead individuals. 4. We provide different examples (springtails, ants, nematodes, daphnia) to show that this non intrusive method is efficient at detecting organisms under a wide variety of conditions even on faintly contrasted and heterogeneous substrates. 5. The repeatability and reliability of this method has been assessed using experimental populations of the Collembola Folsomia candida. 6. We present an ImageJ plugin to automate the analysis of digital pictures of laboratory microcosms. The plugin automates the successive steps of the analysis and recursively analyses multiple sets of images, rapidly producing measurements from a large number of replicated microcosms.

  5. Role of the New South Wales Department of Primary Industries' Laboratory Information Management System (LIMS) in the 2007 equine influenza emergency animal disease response.

    Science.gov (United States)

    Croft, M G; Fraser, G C; Gaul, W N

    2011-07-01

    A Laboratory Information Management System (LIMS) was used to manage the laboratory data and support planning and field activities as part of the response to the equine influenza outbreak in Australia in 2007. The database structure of the LIMS and the system configurations that were made to best handle the laboratory implications of the disease response are discussed. The operational aspects of the LIMS and the related procedures used at the laboratory to process the increased sample throughput are reviewed, as is the interaction of the LIMS with other corporate systems used in the management of the response. Outcomes from this tailored configuration and operation of the LIMS resulted in effective provision and control of the laboratory and laboratory information aspects of the response. The extent and immediate availability of the information provided from the LIMS was critical to some of the activities of key operatives involved in controlling the response. © 2011 The Authors. Australian Veterinary Journal © 2011 Australian Veterinary Association.

  6. A Systematic Approach to Capacity Strengthening of Laboratory Systems for Control of Neglected Tropical Diseases in Ghana, Kenya, Malawi and Sri Lanka

    Science.gov (United States)

    Njelesani, Janet; Dacombe, Russell; Palmer, Tanith; Smith, Helen; Koudou, Benjamin; Bockarie, Moses; Bates, Imelda

    2014-01-01

    Background The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012) on neglected tropical diseases (NTDs). To counter this, capacity strengthening initiatives have been carried out in NTD laboratories worldwide. Many of these initiatives focus on individuals' skills or institutional processes and structures ignoring the crucial interactions between the laboratory and the wider national and international context. Furthermore, rigorous methods to assess these initiatives once they have been implemented are scarce. To address these gaps we developed a set of assessment and monitoring tools that can be used to determine the capacities required and achieved by laboratory systems at the individual, organizational, and national/international levels to support the control of NTDs. Methodology and principal findings We developed a set of qualitative and quantitative assessment and monitoring tools based on published evidence on optimal laboratory capacity. We implemented the tools with laboratory managers in Ghana, Malawi, Kenya, and Sri Lanka. Using the tools enabled us to identify strengths and gaps in the laboratory systems from the following perspectives: laboratory quality benchmarked against ISO 15189 standards, the potential for the laboratories to provide support to national and regional NTD control programmes, and the laboratory's position within relevant national and international networks and collaborations. Conclusion We have developed a set of mixed methods assessment and monitoring tools based on evidence derived from the components needed to strengthen the capacity of laboratory systems to control NTDs. Our tools help to systematically assess and monitor individual, organizational, and wider system level capacity of laboratory systems for NTD control and can be applied in different country contexts. PMID:24603407

  7. A systematic approach to capacity strengthening of laboratory systems for control of neglected tropical diseases in Ghana, Kenya, Malawi and Sri Lanka.

    Directory of Open Access Journals (Sweden)

    Janet Njelesani

    2014-03-01

    Full Text Available The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012 on neglected tropical diseases (NTDs. To counter this, capacity strengthening initiatives have been carried out in NTD laboratories worldwide. Many of these initiatives focus on individuals' skills or institutional processes and structures ignoring the crucial interactions between the laboratory and the wider national and international context. Furthermore, rigorous methods to assess these initiatives once they have been implemented are scarce. To address these gaps we developed a set of assessment and monitoring tools that can be used to determine the capacities required and achieved by laboratory systems at the individual, organizational, and national/international levels to support the control of NTDs.We developed a set of qualitative and quantitative assessment and monitoring tools based on published evidence on optimal laboratory capacity. We implemented the tools with laboratory managers in Ghana, Malawi, Kenya, and Sri Lanka. Using the tools enabled us to identify strengths and gaps in the laboratory systems from the following perspectives: laboratory quality benchmarked against ISO 15189 standards, the potential for the laboratories to provide support to national and regional NTD control programmes, and the laboratory's position within relevant national and international networks and collaborations.We have developed a set of mixed methods assessment and monitoring tools based on evidence derived from the components needed to strengthen the capacity of laboratory systems to control NTDs. Our tools help to systematically assess and monitor individual, organizational, and wider system level capacity of laboratory systems for NTD control and can be applied in different country contexts.

  8. The Jet Propulsion Laboratory Electric and Hybrid Vehicle System Research and Development Project, 1977-1984: A Review

    Science.gov (United States)

    Kurtz, D.; Roan, V.

    1985-01-01

    The JPL Electric and Hybrid Vehicle System Research and Development Project was established in the spring of 1977. Originally administered by the Energy Research and Development Administration (ERDA) and later by the Electric and Hybrid Vehicle Division of the U.S. Department of Energy (DOE), the overall Program objective was to decrease this nation's dependence on foreign petroleum sources by developing the technologies and incentives necessary to bring electric and hybrid vehicles successfully into the marketplace. The ERDA/DOE Program structure was divided into two major elements: (1) technology research and system development and (2) field demonstration and market development. The Jet Propulsion Laboratory (JPL) has been one of several field centers supporting the former Program element. In that capacity, the specific historical areas of responsibility have been: (1) Vehicle system developments (2) System integration and test (3) Supporting subsystem development (4) System assessments (5) Simulation tool development.

  9. Laboratory and Field Test of Movable Conduction-Cooled High-Temperature SMES for Power System Stability Enhancement

    DEFF Research Database (Denmark)

    Fang, Jiakun; Wen, J.; Wang, S.

    2013-01-01

    This paper introduces the first movable conduction-cooled high temperature superconducting magnetic energy storage (SMES) system developed in China. The SMES is rated at 380 V / 35 kJ / 7 kW, consisting of the high temperature magnet confined in a dewar, the cryogenic unit, the converter......, the monitoring and control unit, and the container, etc. The proposed SMES can be loaded onto a truck to move to a desired location and put into operation with easy connection. Laboratory and field tests have been carried out to investigate the operational characteristics and to demonstrate the SMES......’ effectiveness on improvements of system voltage stability and on the oscillation damping. Test results indicate that the SMES system has the features of fast response and four-quadrant power operation. The accessories for the movability of the SEMS system are well designed. The system is feasible to be used...

  10. Laboratory and numerical investigations of kinetic interface sensitive tracers transport for immiscible two-phase flow porous media systems

    Science.gov (United States)

    Tatomir, Alexandru Bogdan A. C.; Sauter, Martin

    2017-04-01

    A number of theoretical approaches estimating the interfacial area between two fluid phases are available (Schaffer et al.,2013). Kinetic interface sensitive (KIS) tracers are used to describe the evolution of fluid-fluid interfaces advancing in two phase porous media systems (Tatomir et al., 2015). Initially developed to offer answers about the supercritical (sc)CO2 plume movement and the efficiency of trapping in geological carbon storage reservoirs, KIS tracers are tested in dynamic controlled laboratory conditions. N-octane and water, analogue to a scCO2 - brine system, are used. The KIS tracer is dissolved in n-octane, which is injected as the non-wetting phase in a fully water saturated porous media column. The porous system is made up of spherical glass beads with sizes of 100-250 μm. Subsequently, the KIS tracer follows a hydrolysis reaction over the n-octane - water interface resulting in an acid and phenol which are both water soluble. The fluid-fluid interfacial area is described numerically with the help of constitutive-relationships derived from the Brooks-Corey model. The specific interfacial area is determined numerically from pore scale calculations, or from different literature sources making use of pore network model calculations (Joekar-Niasar et al., 2008). This research describes the design of the laboratory setup and compares the break-through curves obtained with the forward model and in the laboratory experiment. Furthermore, first results are shown in the attempt to validate the immiscible two phase flow reactive transport numerical model with dynamic laboratory column experiments. Keywords: Fluid-fluid interfacial area, KIS tracers, model validation, CCS, geological storage of CO2

  11. Aircraft Fire Protection Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Navy Aircraft Protection Laboratory provides complete test support for all Navy air vehicle fire protection systems.The facility allows for the simulation of a...

  12. [The practice of development and implementation of quality management systems in medical laboratories. The GOST R ISO 15189-2009 "medical laboratories. The detailed requirements to quality and competence". Particular difficulties of global nature].

    Science.gov (United States)

    Emanuel', A V; Ivanov, G A; Fleganova, I N; Emanuel', V L

    2012-12-01

    The article discusses the methodological issues related to the implementation of international principles of standardization in the format of GOST R ISO 9001-2008 "Quality management systems. Requirements", GOST R ISO 15189-2009 "Medical laboratories. The detailed requirements to quality and competence" and GOST R ISO 18113.1-5 "Medical items for diagnostics in vitro. Information provided by manufacturer (marking)". This approach legibly assigns the responsibility concerning the support of metrological correctness of laboratory measurements. The lacking of both full-value public and sectorial normative documentation and coordinated positions of Rosstandard and Minzdrav of Russia on functioning of medical laboratories is noted.

  13. A Hardware-and-Software System for Experimental Studies of the Acoustic Startle Response in Laboratory Rodents.

    Science.gov (United States)

    Pevtsov, E F; Storozheva, Z I; Proshin, A T; Pevtsova, E I

    2016-02-01

    We developed and tested a novel hardware-and-software system for recording the amplitude of the acoustic startle response in rodents. In our experiments, the baseline indexes of acoustic startle response in laboratory rats and pre-stimulation inhibition under the standard delivery of acoustic stimulation were similar to those evaluated by other investigators on foreign devices. The proposed system is relatively cheap and provides the possibility of performing experiments on freely moving specimens. It should be emphasized that the results of studies can be processed with free-access software.

  14. Implementation of the OECD principles of good laboratory practice in test facilities complying with a quality system accredited to the ISO/IEC 17025 standard.

    Science.gov (United States)

    Feller, Etty

    2008-01-01

    Laboratories with a quality system accredited to the ISO/IEC 17025 standard have a definite advantage, compared to non-accredited laboratories, when preparing their facilities for the implementation of the principles of good laboratory practice (GLP) of the Organisation for Economic Co-operation and Development (OECD). Accredited laboratories have an established quality system covering the administrative and technical issues specified in the standard. The similarities and differences between the ISO/IEC 17025 standard and the OECD principles of GLP are compared and discussed.

  15. FPGA-Based Laboratory Assignments for NoC-Based Manycore Systems

    Science.gov (United States)

    Ttofis, C.; Theocharides, T.; Michael, M. K.

    2012-01-01

    Manycore systems have emerged as being one of the dominant architectural trends in next-generation computer systems. These highly parallel systems are expected to be interconnected via packet-based networks-on-chip (NoC). The complexity of such systems poses novel and exciting challenges in academia, as teaching their design requires the students…

  16. Biomedical Science, Unit IV: The Nervous System in Health and Medicine. The Nervous System; Disorders of the Brain and Nervous System; Application of Computer Science to Diagnosis; Drugs and Pharmacology; The Human Senses; Electricity. Laboratory Manual. Revised Version, 1976.

    Science.gov (United States)

    Biomedical Interdisciplinary Curriculum Project, Berkeley, CA.

    Designed to accompany the student text on the nervous system, this manual presents laboratory activities dealing with concepts presented in the text. Thirty-seven activities are described. Four supplementary activities dealing with concepts in electricity are also included. Laboratory activities are divided into several parts, each part covering a…

  17. Technical evaluation of two 6-kW mono-Si photovoltaic systems at the National Renewable Energy Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Dyk, E.E. van; Strand, T.; Hansen, R.

    1996-05-01

    This paper presents an analysis of performance data on the two 6-kW{sub ac} grid-connected photovoltaic systems at the National Renewable Energy Laboratory (NREL). The performance parameters analyzed include dc and ac power, aperture efficiency, energy, capacity factor and performance index which are compared to plane-of-array irradiance, ambient temperature, and back-of-module temperature as a function of time, either daily or monthly. Power ratings of the systems were also obtained for data corresponding to different test conditions. This study has shown, in addition to expected seasonal trends, that system monitoring is a valuable tool in assessing performance and detecting faulty equipment. In addition, methods applied for this study may be used to evaluate and compare systems employing different cell technologies.

  18. Assessment of the dye removal capability of submersed aquatic plants in a laboratory-scale wetland system using anova

    Directory of Open Access Journals (Sweden)

    O. Keskinkan

    2007-06-01

    Full Text Available The textile dye (Basic Blue 41(BB41 removal capability of a laboratory-scale wetland system was presented in this study. Twenty glass aquaria were used to establish the wetland. Myriophyllum spicatum and Ceratophyllum demersum were planted in the aquaria and acclimated. After establishing flow conditions, the aquaria were fed with synthetic wastewaters containing BB41. The concentration of the dye was adjusted to 11.0 mg/L in the synthetic wastewater. Hydraulic retention times (HRTs ranged between 3 and 18 days. Effective HRTs were 9 and 18 days. The highest dye removal rates were 94.8 and 94.1% for M. spicatum and C. demersum aquaria respectively. The statistical ANOVA method was used to assess the dye removal capability of the wetland system. In all cases the ANOVA method revealed that plants in the wetland system and HRT were important factors and the wetland system was able to remove the dye from influent wastewater.

  19. The Henry Ford Production System: LEAN Process Redesign Improves Service in the Molecular Diagnostic Laboratory

    Science.gov (United States)

    Cankovic, Milena; Varney, Ruan C.; Whiteley, Lisa; Brown, Ron; D'Angelo, Rita; Chitale, Dhananjay; Zarbo, Richard J.

    2009-01-01

    Accurate and timely molecular test results play an important role in patient management; consequently, there is a customer expectation of short testing turnaround times. Baseline data analysis revealed that the greatest challenge to timely result generation occurred in the preanalytic phase of specimen collection and transport. Here, we describe our efforts to improve molecular testing turnaround times by focusing primarily on redesign of preanalytic processes using the principles of LEAN production. Our goal was to complete greater than 90% of the molecular tests in less than 3 days. The project required cooperation from different laboratory disciplines as well as individuals outside of the laboratory. The redesigned processes involved defining and standardizing the protocols and approaching blood and tissue specimens as analytes for molecular testing. The LEAN process resulted in fewer steps, approaching the ideal of a one-piece flow for specimens through collection/retrieval, transport, and different aspects of the testing process. The outcome of introducing the LEAN process has been a 44% reduction in molecular test turnaround time for tissue specimens, from an average of 2.7 to 1.5 days. In addition, extending LEAN work principles to the clinician suppliers has resulted in a markedly increased number of properly collected and shipped blood specimens (from 50 to 87%). These continuous quality improvements were accomplished by empowered workers in a blame-free environment and are now being sustained with minimal management involvement. PMID:19661386

  20. Laboratory core flooding experimental systems for CO2 geosequestration: An updated review over the past decade

    Directory of Open Access Journals (Sweden)

    Yankun Sun

    2016-02-01

    Full Text Available Carbon dioxide (CO2 geosequestration in deep saline aquifers has been currently deemed as a preferable and practicable mitigation means for reducing anthropogenic greenhouse gases (GHGs emissions to the atmosphere, as deep saline aquifers can offer the greatest potential from a capacity point of view. Hence, research on core-scale CO2/brine multiphase migration processes is of great significance for precisely estimating storage efficiency, ensuring storage security, and predicting the long-term effects of the sequestered CO2 in subsurface saline aquifers. This review article initially presents a brief description of the essential aspects of CO2 subsurface transport and geological trapping mechanisms, and then outlines the state-of-the-art laboratory core flooding experimental apparatus that has been adopted for simulating CO2 injection and migration processes in the literature over the past decade. Finally, a summary of the characteristics, components and applications of publicly reported core flooding equipment as well as major research gaps and areas in need of further study are given in relevance to laboratory-scale core flooding experiments in CO2 geosequestration under reservoir conditions.

  1. Lunar laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Keaton, P.W.; Duke, M.B.

    1986-01-01

    An international research laboratory can be established on the Moon in the early years of the 21st Century. It can be built using the transportation system now envisioned by NASA, which includes a space station for Earth orbital logistics and orbital transfer vehicles for Earth-Moon transportation. A scientific laboratory on the Moon would permit extended surface and subsurface geological exploration; long-duration experiments defining the lunar environment and its modification by surface activity; new classes of observations in astronomy; space plasma and fundamental physics experiments; and lunar resource development. The discovery of a lunar source for propellants may reduce the cost of constructing large permanent facilities in space and enhance other space programs such as Mars exploration. 29 refs.

  2. Combining Cloud Networks and Course Management Systems for Enhanced Analysis in Teaching Laboratories

    Science.gov (United States)

    Abrams, Neal M.

    2012-01-01

    A cloud network system is combined with standard computing applications and a course management system to provide a robust method for sharing data among students. This system provides a unique method to improve data analysis by easily increasing the amount of sampled data available for analysis. The data can be shared within one course as well as…

  3. Implementation of a Precast Inverted T-Beam System in Virginia: Part I : Laboratory Investigations

    Science.gov (United States)

    2017-10-01

    The inverted T-beam system provides an accelerated bridge construction alternative for short-to-medium-span bridges. The system consists of adjacent precast inverted T-beams with a cast-in-place concrete topping. This bridge system is not expected to...

  4. Experimental Investigations on the Surface-Driven Capillary Flow of Aqueous Microparticle Suspensions in the Microfluidic Laboratory-On Systems

    Science.gov (United States)

    Mukhopadhyay, Subhadeep

    In this work, total 1592 individual leakage-free polymethylmethacrylate (PMMA) microfluidic devices as laboratory-on-a-chip systems are fabricated by maskless lithography, hot embossing lithography, and direct bonding technique. Total 1094 individual Audio Video Interleave Files as experimental outputs related to the surface-driven capillary flow have been recorded and analyzed. The influence of effective viscosity, effect of surface wettability, effect of channel aspect ratio, and effect of centrifugal force on the surface-driven microfluidic flow of aqueous microparticle suspensions have been successfully and individually investigated in these laboratory-on-a-chip systems. Also, 5 micron polystyrene particles have been separated from the aqueous microparticle suspensions in the microfluidic lab-on-a-chip systems of modified design with 98% separation efficiency, and 10 micron polystyrene particles have been separated with 100% separation efficiency. About the novelty of this work, the experimental investigations have been performed on the surface-driven microfluidic flow of aqueous microparticle suspensions with the investigations on the separation time in particle-size based separation mechanism to control these suspensions in the microfluidic lab-on-a-chip systems. This research work contains a total of 10,112 individual experimental outputs obtained using total 30 individual instruments by author’s own hands-on completely during more than three years continuously. Author has performed the experimental investigations on both the fluid statics and fluid dynamics to develop an automated fluid machine.

  5. A Simple and Low-Cost Monitoring System to Investigate Environmental Conditions in a Biological Research Laboratory.

    Science.gov (United States)

    Gurdita, Akshay; Vovko, Heather; Ungrin, Mark

    2016-01-01

    Basic equipment such as incubation and refrigeration systems plays a critical role in nearly all aspects of the traditional biological research laboratory. Their proper functioning is therefore essential to ensure reliable and repeatable experimental results. Despite this fact, in many academic laboratories little attention is paid to validating and monitoring their function, primarily due to the cost and/or technical complexity of available commercial solutions. We have therefore developed a simple and low-cost monitoring system that combines a "Raspberry Pi" single-board computer with USB-connected sensor interfaces to track and log parameters such as temperature and pressure, and send email alert messages as appropriate. The system is controlled by open-source software, and we have also generated scripts to automate software setup so that no background in programming is required to install and use it. We have applied it to investigate the behaviour of our own equipment, and present here the results along with the details of the monitoring system used to obtain them.

  6. A Simple and Low-Cost Monitoring System to Investigate Environmental Conditions in a Biological Research Laboratory.

    Directory of Open Access Journals (Sweden)

    Akshay Gurdita

    Full Text Available Basic equipment such as incubation and refrigeration systems plays a critical role in nearly all aspects of the traditional biological research laboratory. Their proper functioning is therefore essential to ensure reliable and repeatable experimental results. Despite this fact, in many academic laboratories little attention is paid to validating and monitoring their function, primarily due to the cost and/or technical complexity of available commercial solutions. We have therefore developed a simple and low-cost monitoring system that combines a "Raspberry Pi" single-board computer with USB-connected sensor interfaces to track and log parameters such as temperature and pressure, and send email alert messages as appropriate. The system is controlled by open-source software, and we have also generated scripts to automate software setup so that no background in programming is required to install and use it. We have applied it to investigate the behaviour of our own equipment, and present here the results along with the details of the monitoring system used to obtain them.

  7. Building and Rebuilding: The National Public Health Laboratory Systems and Services Before and After the Earthquake and Cholera Epidemic, Haiti, 2009-2015.

    Science.gov (United States)

    Jean Louis, Frantz; Buteau, Josiane; Boncy, Jacques; Anselme, Renette; Stanislas, Magalie; Nagel, Mary C; Juin, Stanley; Charles, Macarthur; Burris, Robert; Antoine, Eva; Yang, Chunfu; Kalou, Mireille; Vertefeuille, John; Marston, Barbara J; Lowrance, David W; Deyde, Varough

    2017-10-01

    Before the 2010 devastating earthquake and cholera outbreak, Haiti's public health laboratory systems were weak and services were limited. There was no national laboratory strategic plan and only minimal coordination across the laboratory network. Laboratory capacity was further weakened by the destruction of over 25 laboratories and testing sites at the departmental and peripheral levels and the loss of life among the laboratory health-care workers. However, since 2010, tremendous progress has been made in building stronger laboratory infrastructure and training a qualified public health laboratory workforce across the country, allowing for decentralization of access to quality-assured services. Major achievements include development and implementation of a national laboratory strategic plan with a formalized and strengthened laboratory network; introduction of automation of testing to ensure better quality of results and diversify the menu of tests to effectively respond to outbreaks; expansion of molecular testing for tuberculosis, human immunodeficiency virus, malaria, diarrheal and respiratory diseases; establishment of laboratory-based surveillance of epidemic-prone diseases; and improvement of the overall quality of testing. Nonetheless, the progress and gains made remain fragile and require the full ownership and continuous investment from the Haitian government to sustain these successes and achievements.

  8. Post-rehabilitation evaluation of the sanitary sewer system at Lawrence Livermore National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Royal, D.

    1995-11-01

    We are updating a CH2M Hill study which found that the sanitary sewer system is sufficient to transport peak dry weather flow. However, under peak wet weather conditions, the system has insufficient capacity to transport the projected flows for existing and future development. This is due to the amount of infiltration/inflow (I/I) that enters the sewer system when it rains. Our goal is to examine the existing system to determine its adequacy to accommodate present and future peak flows, and also to further update and improve the CH2M Hill study. A set of alternatives was also developed to address deficiencies of the existing system.

  9. Robofurnace: A semi-automated laboratory chemical vapor deposition system for high-throughput nanomaterial synthesis and process discovery

    Energy Technology Data Exchange (ETDEWEB)

    Oliver, C. Ryan; Westrick, William; Koehler, Jeremy; Brieland-Shoultz, Anna; Anagnostopoulos-Politis, Ilias; Cruz-Gonzalez, Tizoc [Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109 (United States); Hart, A. John, E-mail: ajhart@mit.edu [Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan 48109 (United States); Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)

    2013-11-15

    Laboratory research and development on new materials, such as nanostructured thin films, often utilizes manual equipment such as tube furnaces due to its relatively low cost and ease of setup. However, these systems can be prone to inconsistent outcomes due to variations in standard operating procedures and limitations in performance such as heating and cooling rates restrict the parameter space that can be explored. Perhaps more importantly, maximization of research throughput and the successful and efficient translation of materials processing knowledge to production-scale systems, relies on the attainment of consistent outcomes. In response to this need, we present a semi-automated lab-scale chemical vapor deposition (CVD) furnace system, called “Robofurnace.” Robofurnace is an automated CVD system built around a standard tube furnace, which automates sample insertion and removal and uses motion of the furnace to achieve rapid heating and cooling. The system has a 10-sample magazine and motorized transfer arm, which isolates the samples from the lab atmosphere and enables highly repeatable placement of the sample within the tube. The system is designed to enable continuous operation of the CVD reactor, with asynchronous loading/unloading of samples. To demonstrate its performance, Robofurnace is used to develop a rapid CVD recipe for carbon nanotube (CNT) forest growth, achieving a 10-fold improvement in CNT forest mass density compared to a benchmark recipe using a manual tube furnace. In the long run, multiple systems like Robofurnace may be linked to share data among laboratories by methods such as Twitter. Our hope is Robofurnace and like automation will enable machine learning to optimize and discover relationships in complex material synthesis processes.

  10. Robofurnace: A semi-automated laboratory chemical vapor deposition system for high-throughput nanomaterial synthesis and process discovery

    Science.gov (United States)

    Oliver, C. Ryan; Westrick, William; Koehler, Jeremy; Brieland-Shoultz, Anna; Anagnostopoulos-Politis, Ilias; Cruz-Gonzalez, Tizoc; Hart, A. John

    2013-11-01

    Laboratory research and development on new materials, such as nanostructured thin films, often utilizes manual equipment such as tube furnaces due to its relatively low cost and ease of setup. However, these systems can be prone to inconsistent outcomes due to variations in standard operating procedures and limitations in performance such as heating and cooling rates restrict the parameter space that can be explored. Perhaps more importantly, maximization of research throughput and the successful and efficient translation of materials processing knowledge to production-scale systems, relies on the attainment of consistent outcomes. In response to this need, we present a semi-automated lab-scale chemical vapor deposition (CVD) furnace system, called "Robofurnace." Robofurnace is an automated CVD system built around a standard tube furnace, which automates sample insertion and removal and uses motion of the furnace to achieve rapid heating and cooling. The system has a 10-sample magazine and motorized transfer arm, which isolates the samples from the lab atmosphere and enables highly repeatable placement of the sample within the tube. The system is designed to enable continuous operation of the CVD reactor, with asynchronous loading/unloading of samples. To demonstrate its performance, Robofurnace is used to develop a rapid CVD recipe for carbon nanotube (CNT) forest growth, achieving a 10-fold improvement in CNT forest mass density compared to a benchmark recipe using a manual tube furnace. In the long run, multiple systems like Robofurnace may be linked to share data among laboratories by methods such as Twitter. Our hope is Robofurnace and like automation will enable machine learning to optimize and discover relationships in complex material synthesis processes.

  11. A new laboratory-based surveillance system (Respiratory DataMart System) for influenza and other respiratory viruses in England: results and experience from 2009 to 2012.

    Science.gov (United States)

    Zhao, H; Green, H; Lackenby, A; Donati, M; Ellis, J; Thompson, C; Bermingham, A; Field, J; Sebastianpillai, P; Zambon, M; Watson, Jm; Pebody, R

    2014-01-23

    During the 2009 influenza A(H1N1) pandemic, a new laboratory-based virological sentinel surveillance system, the Respiratory DataMart System (RDMS), was established in a network of 14 Health Protection Agency (now Public Health England (PHE)) and National Health Service (NHS) laboratories in England. Laboratory results (both positive and negative) were systematically collected from all routinely tested clinical respiratory samples for a range of respiratory viruses including influenza, respiratory syncytial virus (RSV), rhinovirus, parainfluenza virus, adenovirus and human metapneumovirus (hMPV). The RDMS also monitored the occurrence of antiviral resistance of influenza viruses. Data from the RDMS for the 2009–2012 period showed that the 2009 pandemic influenza virus caused three waves of activity with different intensities during the pandemic and post pandemic periods. Peaks in influenza A(H1N1)pdm09 positivity (defined as number of positive samples per total number of samples tested) were seen in summer and autumn in 2009, with slightly higher peak positivity observed in the first post-pandemic season in 2010/2011. The influenza A(H1N1)pdm09 virus strain almost completely disappeared in the second postpandemic season in 2011/2012. The RDMS findings are consistent with other existing community-based virological and clinical surveillance systems. With a large sample size, this new system provides a robust supplementary mechanism, through the collection of routinely available laboratory data at minimum extra cost, to monitor influenza as well as other respiratory virus activity. A near real-time, daily reporting mechanism in the RDMS was established during the London 2012 Olympic and Paralympic Games. Furthermore, this system can be quickly adapted and used to monitor future influenza pandemics and other major outbreaks of respiratory infectious disease, including novel pathogens.

  12. Neoplasia and Neoplasm Associated Lesions in Laboratory Colonies of Zebrafish Emphasizing Key Influences of Diet and Aquaculture System Design

    Science.gov (United States)

    Spitsbergen, Jan M.; Buhler, Donald R.; Peterson, Tracy S.

    2014-01-01

    During the past decade the zebrafish has emerged as a leading model for mechanistic cancer research due to its sophisticated genetic and genomic resources, its tractability for tissue targeting of transgene expression, its efficiency for forward genetic approaches to cancer model development, and its cost-effectiveness for enhancer and suppressor screens once a cancer model is established. However, in contrast to other laboratory animal species widely used as cancer models, much basic cancer biology information is lacking in zebrafish. As yet data are not published regarding dietary influences on neoplasm incidences in zebrafish. Little information is available regarding spontaneous tumor incidences or histologic types in wild-type (wt) lines of zebrafish. So far a comprehensive database documenting the full spectrum of neoplasia in various organ systems and tissues in not available for zebrafish as it is for other intensely studied laboratory animal species. This manuscript confirms that as in other species diet and husbandry can profoundly influence tumor incidences and histologic spectra in zebrafish. We show that in many laboratory colonies wt lines of zebrafish exhibit elevated neoplasm incidences and neoplasm associated lesions such as heptocyte megalocytosis. We present experimental evidence showing that certain diet and water management regimens can result in high incidences of neoplasia and neoplasm associated lesions. We document the wide array of benign and malignant neoplasms affecting nearly every organ, tissue and cell type in zebrafish, in some cases as a spontaneous aging change, and in other cases due to carcinogen treatment or genetic manipulation. PMID:23382343

  13. Review of EMR monitoring systems developed by the Mobile Radiocommunications Laboratory, National technical University of Athens

    Directory of Open Access Journals (Sweden)

    Popescu Ileana

    2014-01-01

    Full Text Available The purpose of this paper is to present fully automated systems that monitors on a real time basis the non-ionizing electromagnetic radiation emitted by wireless networks. The presented radio monitoring systems aim to perform repetitive and reliable measurements by using a well-defined measurement algorithm as well as high quality calibrated equipment and to inform the public - using the widespread web technologies - about the levels of the electromagnetic radiation emitted by any wireless telecommunication system.

  14. Does System Dynamics Help People to Solve Simple Dynamic Problems? - A Laboratory Experiment

    OpenAIRE

    Grösser, Stefan N.

    2005-01-01

    The Methodology of System Dynamics claims to promote understanding of complex systems. Accepting this claim, the question arises ‘Does experience or an education in System Dynamics help people to solve simple, dynamic problems?'. It guides the conduction of our experiment. The first hypothesis about no influence of additional information for problem solving has to be accepted. The performances of two different information treatment groups are not significantly different. Our second hypothe...

  15. Study of Adversarial and Defensive Components in an Experimental Machinery Control Systems Laboratory Environment

    Science.gov (United States)

    2014-09-01

    survey. Most organizations operating industrial automation and control systems have moved away from proprietary operating systems , which use individual...65 x Figure 43. WireShark packet capture—PLCScan request using Function Code 43 .........65 Figure 44. WireShark packet capture—Wago PLC ...search engine created by John Matherly, to locate systems accessible from the Internet by using meta-data stored in service banners [3]. It searches

  16. Helmet-Mounted Display Research Capabilities of the NASA/Army Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL)

    Science.gov (United States)

    Jacobsen, R. A.; Bivens, C. C.; Rediess, N. A.; Hindson, W. S.; Aiken, E. W.; Aiken, Edwin W. (Technical Monitor)

    1995-01-01

    The Rotorcraft Aircrew Systems Concepts Airborne Laboratory (RASCAL) is a UH-60A Black Hawk helicopter that is being modified by the US Army and NASA for flight systems research. The principal systems that are being installed in the aircraft are a Helmet Mounted Display (HMD) and imaging system, and a programmable full authority Research Flight Control System (RFCS). In addition, comprehensive instrumentation of both the rigid body of the helicopter and the rotor system is provided. The paper will describe the capabilities of these systems and their current state of development. A brief description of initial research applications is included. The wide (40 X 60 degree) field-of-view HMD system has been provided by Kaiser Electronics. It can be configured as a monochromatic system for use in bright daylight conditions, a two color system for darker ambients, or a full color system for use in night viewing conditions. Color imagery is achieved using field sequential video and a mechanical color wheel. In addition to the color symbology, high resolution computer-gene rated imagery from an onboard Silicon Graphics Reality Engine Onyx processor is available for research in virtual reality applications. This synthetic imagery can also be merged with real world video from a variety of imaging systems that can be installed easily on the front of the helicopter. These sensors include infrared or tv cameras, or potentially small millimeter wave radars. The Research Flight Control System is being developed for the aircraft by a team of contractors led by Boeing Helicopters. It consists of a full authority high bandwidth fly-by-wire actuators that drive the main rotor swashplate actuators and the tail rotor actuator in parallel. This arrangement allows the basic mechanical flight control system of the Black Hawk to be retained so that the safety pilot can monitor the operation of the system through the action of his own controls. The evaluation pilot will signal the fly

  17. Automatic opening system for radioactive source in teaching laboratory; Sistema automatico de abertura de fonte radiativa em laboratorio de ensino

    Energy Technology Data Exchange (ETDEWEB)

    Seren, Maria Emilia Gibin, E-mail: mseren@ifi.unicamp.br [Universidade Estadual de Campinas (LEB/IFGW/UNICAMP), SP (Brazil). Inst. de Fisica Gleb Wataghin. Lab. de Ensino em Fisica Medica; Gaal, Vladimir, E-mail: vladimir@ifi.unicamp.br [Universidade Estadual de Campinas (LEB/IFGW/UNICAMP), SP (Brazil). Inst. de Fisica Gleb Wataghin. Lab. de Eletronica e Eletricidade; Rodrigues, Varlei, E-mail: varlei@ifi.unicamp.br [Universidade Estadual de Campinas (DFA/IFGW/UNICAMP), SP (Brazil). Inst. de Fisica Gleb Wataghin. Dept. de Fisica Aplicada; Morais, Sergio Luiz de, E-mail: ceelinho@ifi.unicamp.br [Universidade Estadual de Campinas (CST-Mec/IFGW/UNICAMP), SP (Brazil). Inst. de Fisica Gleb Wataghin. Oficina Mecanica

    2013-07-01

    Compton scattering phenomenon is experimentally studied during the medical physics laboratory course at the University of Campinas (UNICAMP). The Teaching Laboratory of Medical Physics from IFGW/UNICAMP has a structure for its development: a fixed {sup 137}Cs sealed source with activity 610.5MBq, whose emitted radiation collides on a target, and a scintillation detector that turns around the target and detects scattered photons spectrum. {sup 137}Cs source is stored in a lead shield with a collimating window for the gamma radiation emitted with energy of 0.662MeV. This source is exposed only when attenuation barrier protecting the collimating window is opened. The process of opening and closing the attenuation barrier may deliver radiation dose to users when done manually. Taking into account the stochastic harmful effects of ionizing radiation, the objective of this project was to develop an automatic exposure system of the radioactive source in order to reduce the dose during the Compton scattering experiment. The developed system is micro controlled and performs standard operating routines and responds to emergencies. Electromagnetic lock enables quick closing barrier by gravity in case of interruption of electrical current circuit. Besides reducing the total dose of lab users, the system adds more security in the routine since it limits access to the source and prevents accidental exposure. (author)

  18. Can Unmanned Aerial Systems (Drones Be Used for the Routine Transport of Chemistry, Hematology, and Coagulation Laboratory Specimens?

    Directory of Open Access Journals (Sweden)

    Timothy K Amukele

    Full Text Available Unmanned Aerial Systems (UAS or drones could potentially be used for the routine transport of small goods such as diagnostic clinical laboratory specimens. To the best of our knowledge, there is no published study of the impact of UAS transportation on laboratory tests.Three paired samples were obtained from each one of 56 adult volunteers in a single phlebotomy event (336 samples total: two tubes each for chemistry, hematology, and coagulation testing respectively. 168 samples were driven to the flight field and held stationary. The other 168 samples were flown in the UAS for a range of times, from 6 to 38 minutes. After the flight, 33 of the most common chemistry, hematology, and coagulation tests were performed. Statistical methods as well as performance criteria from four distinct clinical, academic, and regulatory bodies were used to evaluate the results.Results from flown and stationary sample pairs were similar for all 33 analytes. Bias and intercepts were <10% and <13% respectively for all analytes. Bland-Altman comparisons showed a mean difference of 3.2% for Glucose and <1% for other analytes. Only bicarbonate did not meet the strictest (Royal College of Pathologists of Australasia Quality Assurance Program performance criteria. This was due to poor precision rather than bias. There were no systematic differences between laboratory-derived (analytic CV's and the CV's of our flown versus terrestrial sample pairs however CV's from the sample pairs tended to be slightly higher than analytic CV's. The overall concordance, based on clinical stratification (normal versus abnormal, was 97%. Length of flight had no impact on the results.Transportation of laboratory specimens via small UASs does not affect the accuracy of routine chemistry, hematology, and coagulation tests results from selfsame samples. However it results in slightly poorer precision for some analytes.

  19. Can Unmanned Aerial Systems (Drones) Be Used for the Routine Transport of Chemistry, Hematology, and Coagulation Laboratory Specimens?

    Science.gov (United States)

    Amukele, Timothy K; Sokoll, Lori J; Pepper, Daniel; Howard, Dana P; Street, Jeff

    2015-01-01

    Unmanned Aerial Systems (UAS or drones) could potentially be used for the routine transport of small goods such as diagnostic clinical laboratory specimens. To the best of our knowledge, there is no published study of the impact of UAS transportation on laboratory tests. Three paired samples were obtained from each one of 56 adult volunteers in a single phlebotomy event (336 samples total): two tubes each for chemistry, hematology, and coagulation testing respectively. 168 samples were driven to the flight field and held stationary. The other 168 samples were flown in the UAS for a range of times, from 6 to 38 minutes. After the flight, 33 of the most common chemistry, hematology, and coagulation tests were performed. Statistical methods as well as performance criteria from four distinct clinical, academic, and regulatory bodies were used to evaluate the results. Results from flown and stationary sample pairs were similar for all 33 analytes. Bias and intercepts were <10% and <13% respectively for all analytes. Bland-Altman comparisons showed a mean difference of 3.2% for Glucose and <1% for other analytes. Only bicarbonate did not meet the strictest (Royal College of Pathologists of Australasia Quality Assurance Program) performance criteria. This was due to poor precision rather than bias. There were no systematic differences between laboratory-derived (analytic) CV's and the CV's of our flown versus terrestrial sample pairs however CV's from the sample pairs tended to be slightly higher than analytic CV's. The overall concordance, based on clinical stratification (normal versus abnormal), was 97%. Length of flight had no impact on the results. Transportation of laboratory specimens via small UASs does not affect the accuracy of routine chemistry, hematology, and coagulation tests results from selfsame samples. However it results in slightly poorer precision for some analytes.

  20. Particle Size Measurements from the first Fundamentals of Ice Crystal Icing Physics Test in the NASA Propulsion Systems Laboratory

    Science.gov (United States)

    King, Michael C.; Bachalo, William; Kurek, Andrzej

    2017-01-01

    This presentation shows particle measurements by the Artium Technologies, Inc. Phase Doppler Interferometer and High Speed Imaging instruments from the first Fundamental Ice Crystal Icing Physics test conducted in the NASA Propulsion Systems Laboratory. The work focuses on humidity sweeps at a larger and a smaller median volumetric diameter. The particle size distribution, number density, and water content measured by the Phase Doppler Interferometer and High Speed Imaging instruments from the sweeps are presented and compared. The current capability for these two instruments to measure and discriminate ICI conditions is examined.

  1. Senior Research Connects Students with a Living Laboratory As Part of an Integrated Crop and Livestock System

    Science.gov (United States)

    Senturklu, Songul; Landblom, Douglas; Brevik, Eric C.

    2015-04-01

    Soil, water, soil microbes, and solar energy are the main sources that sustain life on this planet. Without them working in concert, neither plants nor animals would survive. Considering the efficiency of animal production targets, soil must be protected and improved. Therefore, through our sustainable integrated crop and livestock research, we are studying animal and soil interactions from the soil to the plate. Integrating beef cattle systems into a diverse cropping system is providing a living laboratory for education beyond the traditional classroom setting. To establish the living learning laboratory at the Dickinson Research Extension Center, a five-crop rotation was established that included adapted cool and warm season grasses and broadleaf crops. The crop rotation is: sunflower > hard red spring wheat > fall seeded winter triticale-hairy vetch (hay)/spring seeded 7-species cover crop > Corn (85-95 day varieties) > field pea-barley intercrop. Sunflower and spring wheat are harvested for cash crop income in the rotation. Livestock integration occurs when yearling steers that had previously grazed perennial pastures until mid-August graze field pea-barley and subsequently unharvested corn. Average grazing days for field pea-barley and unharvested corn is 30 and 70 days, respectively. At the end of the grazing period, the yearling steers average 499-544 kg and are moved to a feedlot and fed an additional 75 days until slaughter. Maximizing grazing days and extending the grazing season through integration with the cropping system reduces custom feeding costs and enhances animal profit. Beef cows do not require high quality feed after their calves have been weaned. Therefore, gestating beef cows are an ideal animal to graze cover crops and crop aftermath (residue) after yearling steer grazing and farming operations have been completed. Extending the grazing season for beef cows by grazing cover crops and residues reduces winter feed cost, which is one of the

  2. Blackroom Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Enables evaluation and characterization of materials ranging from the ultraviolet to the longwave infrared (LWIR).DESCRIPTION: The Blackroom Laboratory is...

  3. Photometrics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — Purpose:The Photometrics Laboratory provides the capability to measure, analyze and characterize radiometric and photometric properties of light sources and filters,...

  4. Target Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — [Part of the ATLAS user facility.] The Physics Division operates a target development laboratory that produces targets and foils of various thickness and substrates,...

  5. [Present status of Tsutsugamushi disease detection at regional public health laboratories--a comparison between the results from a questionnaire survey and the National Notifiable Diseases Surveillance System].

    Science.gov (United States)

    Matsui, Tamano; Ogawa, Motohiko; Kisimoto, Toshio; Kaiho, Ikuo; Ohyama, Takaaki; Kobayashi, John; Okabe, Nobuhiko

    2004-03-01

    Tsutsugamushi disease has been a notifiable disease in Japan since the implementation of the Infectious Diseases Control Law in April 1999. In order to assess the role of public health laboratories in detecting Tsutsugamushi disease, a questionnaire regarding routine testing of suspected cases of Tsutsugamushi disease was sent to 73 regional public health laboratories (47 prefectural laboratories and 26 municipal laboratories) in July 2001. The response rate was 92% (67/73 laboratories). It was found that most prefectural laboratories are well prepared to routinely receive and test specimens of suspected Tsutsugamushi disease cases. Additionally, we found that some regional public health laboratories are using two or more detection methods to improve the accuracy of their routine tests. In southern Japan. Kawasaki and Kuroki strains, strains endemic to the region, are widely used in addition to Kato, Karp, and Gilliam strains, the standard strains used for serum antibody tests in Japan. For the years 2000 and 2001, we found that for some prefectures, the annual number of cases confirmed by regional public health laboratories was nearly equal to the annual number of cases the prefecture reported to the National Notifiable Diseases Surveillance System. In these prefectures, it appears that an effective communication network has been established between physicians, public health laboratories, and local health centers, ensuring laboratory confirmation and proper notification.

  6. Establishment of a voluntary electronic Chlamydia trachomatis laboratory surveillance system in Germany, 2008 to 2014.

    Science.gov (United States)

    Dudareva-Vizule, Sandra; Haar, Karin; Sailer, Andrea; Jansen, Klaus; Hamouda, Osamah; Wisplinghoff, Hilmar; Tiemann, Carsten; Pape, Eberhard; Bremer, Viviane

    2017-02-09

    Chlamydia trachomatis (CT) infections are not reportable in Germany and limited data on prevalence are available. CT screening has been offered free of charge to pregnant women since 1995 and to all women under 25 years since 2008. For symptomatic women and men, diagnostic testing is covered by statutory health insurance. We describe the establishment of a nationwide, laboratory-based, voluntary sentinel that electronically collects information on all performed CT tests with test results, test reason and patient information. The sentinel represents one third of all performed CT tests in Germany. In the period from 2008 to 2014, 3,877,588 CT tests were reported, 93% in women. Women aged 20-24 years and men aged 25-29 years were the most frequently tested age groups. The overall proportion of positive tests (PPT) among women was 3.9% and among men 11.0%. The highest PPT among women was in the age groups 15-19 (6.8%) and 20-24 years (5.9%), and among men in the age groups 20-24 (19.2%), 15-19 (15.4%) and 25-29 years (14.8%). The PPT for CT was high among women and men younger than 25 years. Prevention is urgently needed. Monitoring of CT infection in Germany should be continued. This article is copyright of The Authors, 2017.

  7. Relative susceptibility of stream macroinvertebrates to temephos and chlorpyrifos, determined in laboratory continuous-flow systems.

    Science.gov (United States)

    Muirhead-Thomson, R C

    1978-01-01

    Laboratory techniques are described for evaluating the lethal and behavioral impact of pesticides on a range of stream macroinvertebrates under continuous through-flow and simulated stream conditions. The same basic test unit has been used, with slight modifications, to study the reactions of both Simulium larvae and non-target stream invertebrates. On the basis of a standard 1-hr exposure period to different concentrations followed by a 24-hr holding period in a continuous flow of clean water, different test organisms showed wide and consistent differences in tolerance to each of the two insecticides tested. The widest difference between two organisms occurred in the case of the Amphipod, Gammarus pulex (LC90-95, greater than 1 ppm) which was found to be about 5000 x more tolerant to temephos than are nymphs of the mayfly, Baetis rhodani. (LC 90-95, 0.001-0.002 ppm) The widest difference in the reactions of any one species is shown on the part of Gammarus which is about 100 times more susceptible to chlorpyrifos (LC 90-95, 0.05-0.1 ppm) than to temephos. The susceptibility levels of other indicator species such as Agrion, Hydropsyche, Brachycentrus, Ephemera, etc. are discussed in relation to susceptibility levels of Simulium larvae under the same test conditions, and also in relation to current field dosages of the two insecticides in practical and experimental Simulium control.

  8. Formulation development of antibodies using robotic system and high-throughput laboratory (HTL).

    Science.gov (United States)

    Zhao, Hui; Graf, Olivier; Milovic, Nebojsa; Luan, Xiaosong; Bluemel, Markus; Smolny, Markus; Forrer, Kurt

    2010-05-01

    Since each antibody has its unique physical chemical properties, optimal formulation for one antibody is likely not applicable for the others. To rapidly screen multiple antibody formulations, an automated system was constructed to perform sample preparation, testing, and data management. Using the automatic system, up to 500 liquid formulations can be prepared in deep well microplates and further distributed into standard microplates that can be stored under different stress conditions for degradation studies. In addition, the system can also be used to prepare samples in microplates for different analytical measurements such as UV spectroscopy, turbidity, dynamic light scattering (DLS), SEC-HPLC, RP-HPLC and CEX-HPLC, and automated lab-on-a-chip platform (ALP). The data generated using different techniques in the automatic system were comparable to those of the classical approaches.

  9. Synthetic Aperture Ladar (SAL): Fundamental Theory, Design Equations for a Satellite System, and Laboratory Demonstration

    National Research Council Canada - National Science Library

    Lucke, Robert

    2002-01-01

    .... Design equations are presented to allow quick assessment of the hardware parameters required for a notional system, most notably optical aperture sizes and the laser's power, chirp, and pulse rate capabilities...

  10. Performance Modeling and Testing of Distributed Electronics in PV Systems; NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    Deline, C.

    2015-03-18

    Computer modeling is able to predict the performance of distributed power electronics (microinverters, power optimizers) in PV systems. However, details about partial shade and other mismatch must be known in order to give the model accurate information to go on. This talk will describe recent updates in NREL’s System Advisor Model program to model partial shading losses with and without distributed power electronics, along with experimental validation results. Computer modeling is able to predict the performance of distributed power electronics (microinverters, power optimizers) in PV systems. However, details about partial shade and other mismatch must be known in order to give the model accurate information to go on. This talk will describe recent updates in NREL’s System Advisor Model program to model partial shading losses.

  11. The european Laboratory for particle physics uses a new documental system created by a UGR researcher

    CERN Multimedia

    Ruiz, Antonio

    2006-01-01

    "The growing digitalization of traditional libraries and the increase of scientific production, like in the fields of high energies physics, have leaded to consider the manual indexing systems to be obsolete, as they are unviable in practice." (1 page)

  12. A study of the portability of an Ada system in the software engineering laboratory (SEL)

    Science.gov (United States)

    Jun, Linda O.; Valett, Susan Ray

    1990-01-01

    A particular porting effort is discussed, and various statistics on analyzing the portability of Ada and the total staff months (overall and by phase) required to accomplish the rehost, are given. This effort is compared to past experiments on the rehosting of FORTRAN systems. The discussion includes an analysis of the types of errors encountered during the rehosting, the changes required to rehost the system, experiences with the Alsys IBM Ada compiler, the impediments encountered, and the lessons learned during this study.

  13. Flying Electronic Warfare Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Provides NP-3D aircraft host platforms for Effectiveness of Navy Electronic Warfare Systems (ENEWS) Program antiship missile (ASM) seeker simulators used...

  14. GSPEL - Fuel Cell Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Fuel Cell Lab (FCL)Established to investigate, integrate, testand verifyperformance and technology readiness offuel cell systems and fuel reformers for use with...

  15. Detecting Ebola with limited laboratory access in the Democratic Republic of Congo: evaluation of a clinical passive surveillance reporting system.

    Science.gov (United States)

    Ashbaugh, Hayley R; Kuang, Brandon; Gadoth, Adva; Alfonso, Vivian H; Mukadi, Patrick; Doshi, Reena H; Hoff, Nicole A; Sinai, Cyrus; Mossoko, Mathias; Kebela, Benoit Ilunga; Muyembe, Jean-Jacques; Wemakoy, Emile Okitolonda; Rimoin, Anne W

    2017-09-01

    Ebola virus disease (EVD) can be clinically severe and highly fatal, making surveillance efforts for early disease detection of paramount importance. In areas with limited access to laboratory testing, the Integrated Disease Surveillance and Response (IDSR) strategy in the Democratic Republic of Congo (DRC) may be a vital tool in improving outbreak response. Using DRC IDSR data from the nation's four EVD outbreak periods from 2007-2014, we assessed trends of Viral Hemorrhagic Fever (VHF) and EVD differential diagnoses reportable through IDSR. With official case counts from active surveillance of EVD outbreaks, we assessed accuracy of reporting through the IDSR passive surveillance system. Although the active and passive surveillance represent distinct sets of data, the two were correlated, suggesting that passive surveillance based only on clinical evaluation may be a useful predictor of true cases prior to laboratory confirmation. There were 438 suspect VHF cases reported through the IDSR system and 416 EVD cases officially recorded across the outbreaks examined. Although collected prior to official active surveillance cases, case reporting through the IDSR during the 2007, 2008 and 2012 outbreaks coincided with official EVD epidemic curves. Additionally, all outbreak areas experienced increases in suspected cases for both malaria and typhoid fever during EVD outbreaks, underscoring the importance of training health care workers in recognising EVD differential diagnoses and the potential for co-morbidities. © 2017 John Wiley & Sons Ltd.

  16. Standard Practice for Laboratory Screening of Metallic Containment Materials for Use With Liquids in Solar Heating and Cooling Systems

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1980-01-01

    1.1 This practice covers several laboratory test procedures for evaluating corrosion performance of metallic containment materials under conditions similar to those that may occur in solar heating and cooling systems. All test results relate to the performance of the metallic containment material only as a part of a metal/fluid pair. Performance in these laboratory test procedures, taken by itself, does not necessarily constitute an adequate basis for acceptance or rejection of a particular metal/fluid pair in solar heating and cooling systems, either in general or in a particular design. This practice is not intended to preclude the use of other screening tests, particularly when those tests are designed to more closely simulate field service conditions. 1.2 This practice describes apparatus and procedures for several tests, any one or more of which may be used to evaluate the deterioration of the metallic containment material in a metal/fluid pair. The procedures are designed to permit simulation, heating...

  17. Carbonate mineralisation in sabkha microbial mats; a comparative study of field and laboratory systems

    Science.gov (United States)

    Dutton, Kirsten E.; Paul, Andreas; Lessa Andrade, Luiza; Sherry, Angela; Lokier, Stephen; Head, Ian M.; van der Land, Cees

    2017-04-01

    Microbial mats and their lithified counterparts are some of the earliest evidence of life on Earth. The coastal sabkha in Abu Dhabi, United Arab Emirates, is a modern setting where microbial mats flourish in a hypersaline and arid environment. These microbial communities are composed of microbes such as cyanobacteria, thermoplasmata and sulphate-reducing bacteria. The mats thrive as they are protected from predators, which are excluded by the extreme environmental conditions. Microbial mats are highly reactive to change, with their microbial communities and geochemistry varying on a millimetre scale, likely controlling mineralisation processes. Exact carbonate mineralisation rates within coastal sabkha microbial mats have not to date been quantified. Defining the mineralisation pathways and knowledge of precise mineralisation rates will help to explain how these organosedimentary structures are retained in the rock record. A fundamental understanding of the role of microbial mats in the formation of different carbonate phases is important, yet there are also other practical implications. For example, structures observed in core from the oil-bearing Arab Formation have been likened to modern microbial mats in terms of structure and mineralogy. The depositional configuration and primary mineralogy generated by microbial mats may control syndepositional lithification and later diagenesis thereby influencing reservoir porosity and permeability. In order to constrain factors effecting mineralisation and early lithification, experimentation in a controlled laboratory environment is required. Parameters for experimentation have been established during fieldwork and were applied to a tank-based laboratory simulation of sabkha microbial mats. These parameters include light, salinity and cation and anion water chemistry, gas production chemistry and vertical mat growth. Parameters were measured weekly with sampling for mineralogical and microbial community analysis on a

  18. Wide area scanning system and carbon microbeams at the external microbeam facility of the INFN LABEC laboratory in Florence

    Energy Technology Data Exchange (ETDEWEB)

    Giuntini, L. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Dipartimento di Fisica e Astronomia, Università di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Massi, M. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Calusi, S. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Dipartimento di Fisica e Astronomia, Università di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Castelli, L. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Carraresi, L. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Dipartimento di Fisica e Astronomia, Università di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Fedi, M.E.; Gelli, N. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Liccioli, L.; Mandò, P.A.; Mazzinghi, A. [Istituto Nazionale di Fisica Nucleare (INFN), Sezione di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Dipartimento di Fisica e Astronomia, Università di Firenze, Via Sansone 1, I-50019 Sesto Fiorentino, Firenze (Italy); Palla, L. [INFN, Sezione di Pisa and Università di Pisa, Largo B. Pontecorvo 3, I-56127 Pisa (Italy); Romano, F.P. [Consiglio Nazionale delle Ricerche (CNR), Istituto per i Beni Archeologici e Monumentali (IBAM), Via Biblioteca, 4, 95124 Catania (Italy); Istituto Nazionale di Fisica Nucleare (INFN), LNS, Via S.Sofia 62, 95125 Catania (Italy); and others

    2015-04-01

    Recently, developments have been made to the external scanning microbeam of INFN-LABEC laboratory in Florence. A new system for mechanical sample scanning was implemented. This system allows us to acquire large maps (up to 20 × 20 cm{sup 2}), of great interest in the Cultural Heritage field. In parallel, the possibility of using carbon microbeams for experiments, such as, for example, ion beam modification of materials and MeV Secondary Ion Mass Spectrometry, has been investigated. As a test application, Particle Induced X-ray Emission with carbon microbeams has been performed on a lapis lazuli stone. First results for both wide area imaging and external carbon microbeams are briefly reported.

  19. Experience with more productive information systems design at Sandia National Laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, J.K.

    1990-01-01

    The natural language technique was just one of many approaches to information system design in 1987. The success of this approach convinced management of the viability of this new'' approach. A group was created to use natural language in information system specifications and designs. Two of the projects undertaken by this group will be reviewed. The first is a quality database that allows for the management of the process that certifies production capabilities for major weapon components and the second tracks command and control status of weapons. A third external project involving nuclear disarmament will also be discussed.

  20. Integrated ICT System for Teaching Physical Sciences in a Robotic Laboratory

    Directory of Open Access Journals (Sweden)

    Spyros Kopsidas

    2009-11-01

    Full Text Available The Information and Communication Technologies provide economically feasible and effective means to assist individuals with kinetic disabilities in numerous activities concerning educational purposes. As the technology is increasingly used in everyday environments, an early response of the existing methods to teach the Physical Sciences to individuals with kinetic disabilities is our innovative system. The work presented in this article is part of the “Smart and Adaptable Information System for Supporting Physics Experiments in a Robotic Laboratory” (SAIS-PEaRL research project.

  1. Laboratory study of subjective perceptions to low temperature heating systems with exhaust ventilation in Nordic countries

    DEFF Research Database (Denmark)

    Jin, Quan; Simone, Angela; Olesen, Bjarne W.

    2017-01-01

    Given the global trends of rising energy demand and the increasing utilization of low-grade renewable energy, low-temperature heating systems can play key roles in improving building energy efficiency while providing a comfortable indoor environment. To meet the need to retrofit existing buildings...

  2. Design and Configuration of a Medical Imaging Systems Computer Laboratory Syllabus

    Science.gov (United States)

    Selver, M. Alper

    2016-01-01

    Medical imaging systems (MIS) constitute an important emergent subdiscipline of engineering studies. In the context of electrical and electronics engineering (EEE) education, MIS courses cover physics, instrumentation, data acquisition, image formation, modeling, and quality assessment of various modalities. Many well-structured MIS courses are…

  3. Stardust in Laboratory & Evolution of Early Solar System f y S Sy

    Indian Academy of Sciences (India)

    kkmarhas

    2008-09-13

    Sep 13, 2008 ... If a now-extinct nuclide was incorporated “live” into the first forming solids its fossil records can forming solids, its fossil records can be used to record the time of formation. 24Mg 25Mg 26Mg. 26Al 27Al. Presolar Grains &. Evolution of Early Solar System. Kuljeet K. Marhas. 13th September 2008. Physical ...

  4. Laboratory Model of the Cardiovascular System for Experimental Demonstration of Pulse Wave Propagation

    Science.gov (United States)

    Stojadinovic, Bojana; Nestorovic, Zorica; Djuric, Biljana; Tenne, Tamar; Zikich, Dragoslav; Žikic, Dejan

    2017-01-01

    The velocity by which a disturbance moves through the medium is the wave velocity. Pulse wave velocity is among the key parameters in hemodynamics. Investigation of wave propagation through the fluid-filled elastic tube has a great importance for the proper biophysical understanding of the nature of blood flow through the cardiovascular system.…

  5. Dependability for high-tech systems: an industry-as-laboratory approach

    NARCIS (Netherlands)

    Brinksma, Hendrik; Hooman, J.

    2007-01-01

    The dependability of high-volume embedded systems, such a consumer electronic devices, is threatened by a combination of quickly increasing complexity, decreasing time-to-market, and strong cost constraints. This poses challenging research questions that are investigated in the Trader project,

  6. Dependability for high-tech systems: an industry-as-laboratory approach

    NARCIS (Netherlands)

    Brinksma, Hendrik; Hooman, Jozef

    2008-01-01

    The dependability of high-volume embedded systems, such a consumer electronic devices, is threatened by a combination of quickly increasing complexity, decreasing time-to-market, and strong cost constraints. This poses challenging research questions that are investigated in the Trader project,

  7. Fingering in unsaturated zone flow: a qualitative review with laboratory experiments on heterogeneous systems

    CSIR Research Space (South Africa)

    Sililo, OTN

    2000-11-01

    Full Text Available of flow will be greatest where the fine-grained layer is thinnest; (5) surface depressions in an upper fine-grained layer will concentrate flow, with fingers forming below such areas; and (6) in systems where an upper fine-grained layer has macro pores...

  8. Laboratory study of subjective perceptions to low temperature heating systems with exhaust ventilation in Nordic countries

    DEFF Research Database (Denmark)

    Jin, Quan; Simone, Angela; Olesen, Bjarne W.

    2017-01-01

    Given the global trends of rising energy demand and the increasing utilization of low-grade renewable energy, low-temperature heating systems can play key roles in improving building energy efficiency while providing a comfortable indoor environment. To meet the need to retrofit existing building...

  9. Embedding Mixed-Reality Laboratories into E-Learning Systems for Engineering Education

    Science.gov (United States)

    Al-Tikriti, Munther N.; Al-Aubidy, Kasim M.

    2013-01-01

    E-learning, virtual learning and mixed reality techniques are now a global integral part of the academic and educational systems. They provide easier access to educational opportunities to a very wide spectrum of individuals to pursue their educational and qualification objectives. These modern techniques have the potentials to improve the quality…

  10. Laboratory Testing of Solar Combi System with Compact Long Term PCM Heat Storage

    DEFF Research Database (Denmark)

    Johansen, Jakob Berg; Englmair, Gerald; Dannemand, Mark

    2016-01-01

    ) can provide a more compact way of storing heat. Sodium acetate trihydrate (SAT) is a good candidate material as it has a relatively high heat of fusion and in addition it has the ability to supercool to room temperature without solidifying. In this paper results from the test of a solar combi system...

  11. Science Faculty Belief Systems in a Professional Development Program: Inquiry in College Laboratories

    Science.gov (United States)

    Hutchins, Kristen L.; Friedrichsen, Patricia J.

    2012-01-01

    The purpose of this study was to investigate how science faculty members' belief systems about inquiry-based teaching changed through their experience in a professional development program. The program was designed to support early career science faculty in learning about inquiry and incorporating an inquiry-based approach to teaching…

  12. A Stand-Alone Information System for Small Air Force Hospital Laboratories.

    Science.gov (United States)

    1986-01-01

    Counter6 [40, p. 1921 (figures 1.3 and 1.4) established industry standards in automated chem- istry and hematology analyses, respectively. The high...old system, some- times called the "cold turkey " approach.. 0 2. Parallel Conversion. Parallel conversion is an approach wherein both the old and the

  13. Seed Storage Proteins as a System for Teaching Protein Identification by Mass Spectrometry in Biochemistry Laboratory

    Science.gov (United States)

    Wilson, Karl A.; Tan-Wilson, Anna

    2013-01-01

    Mass spectrometry (MS) has become an important tool in studying biological systems. One application is the identification of proteins and peptides by the matching of peptide and peptide fragment masses to the sequences of proteins in protein sequence databases. Often prior protein separation of complex protein mixtures by 2D-PAGE is needed,…

  14. Evaluation of the enterovirus laboratory surveillance system in Denmark, 2010 to 2013

    DEFF Research Database (Denmark)

    Condell, Orla; Midgley, Sofie; Christiansen, C B

    2016-01-01

    The primary aim of the Danish enterovirus (EV) surveillance system is to document absence of poliovirus infection. The conflict in Syria has left many children unvaccinated and movement from areas with polio cases to Europe calls for increased awareness to detect and respond to virus-transmission...

  15. PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities

    Directory of Open Access Journals (Sweden)

    Baldwin Stephen A

    2011-03-01

    Full Text Available Abstract Background Facilities that provide a service for DNA sequencing typically support large numbers of users and experiment types. The cost of services is often reduced by the use of liquid handling robots but the efficiency of such facilities is hampered because the software for such robots does not usually integrate well with the systems that run the sequencing machines. Accordingly, there is a need for software systems capable of integrating different robotic systems and managing sample information for DNA sequencing services. In this paper, we describe an extension to the Protein Information Management System (PIMS that is designed for DNA sequencing facilities. The new version of PIMS has a user-friendly web interface and integrates all aspects of the sequencing process, including sample submission, handling and tracking, together with capture and management of the data. Results The PIMS sequencing extension has been in production since July 2009 at the University of Leeds DNA Sequencing Facility. It has completely replaced manual data handling and simplified the tasks of data management and user communication. Samples from 45 groups have been processed with an average throughput of 10000 samples per month. The current version of the PIMS sequencing extension works with Applied Biosystems 3130XL 96-well plate sequencer and MWG 4204 or Aviso Theonyx liquid handling robots, but is readily adaptable for use with other combinations of robots. Conclusions PIMS has been extended to provide a user-friendly and integrated data management solution for DNA sequencing facilities that is accessed through a normal web browser and allows simultaneous access by multiple users as well as facility managers. The system integrates sequencing and liquid handling robots, manages the data flow, and provides remote access to the sequencing results. The software is freely available, for academic users, from http://www.pims-lims.org/.

  16. PIMS sequencing extension: a laboratory information management system for DNA sequencing facilities.

    Science.gov (United States)

    Troshin, Peter V; Postis, Vincent Lg; Ashworth, Denise; Baldwin, Stephen A; McPherson, Michael J; Barton, Geoffrey J

    2011-03-07

    Facilities that provide a service for DNA sequencing typically support large numbers of users and experiment types. The cost of services is often reduced by the use of liquid handling robots but the efficiency of such facilities is hampered because the software for such robots does not usually integrate well with the systems that run the sequencing machines. Accordingly, there is a need for software systems capable of integrating different robotic systems and managing sample information for DNA sequencing services. In this paper, we describe an extension to the Protein Information Management System (PIMS) that is designed for DNA sequencing facilities. The new version of PIMS has a user-friendly web interface and integrates all aspects of the sequencing process, including sample submission, handling and tracking, together with capture and management of the data. The PIMS sequencing extension has been in production since July 2009 at the University of Leeds DNA Sequencing Facility. It has completely replaced manual data handling and simplified the tasks of data management and user communication. Samples from 45 groups have been processed with an average throughput of 10000 samples per month. The current version of the PIMS sequencing extension works with Applied Biosystems 3130XL 96-well plate sequencer and MWG 4204 or Aviso Theonyx liquid handling robots, but is readily adaptable for use with other combinations of robots. PIMS has been extended to provide a user-friendly and integrated data management solution for DNA sequencing facilities that is accessed through a normal web browser and allows simultaneous access by multiple users as well as facility managers. The system integrates sequencing and liquid handling robots, manages the data flow, and provides remote access to the sequencing results. The software is freely available, for academic users, from http://www.pims-lims.org/.

  17. A New Laboratory Radio Frequency Identification (RFID System for Behavioural Tracking of Marine Organisms

    Directory of Open Access Journals (Sweden)

    Francesc Sardà

    2011-10-01

    Full Text Available Radio frequency identification (RFID devices are currently used to quantify several traits of animal behaviour with potential applications for the study of marine organisms. To date, behavioural studies with marine organisms are rare because of the technical difficulty of propagating radio waves within the saltwater medium. We present a novel RFID tracking system to study the burrowing behaviour of a valuable fishery resource, the Norway lobster (Nephrops norvegicus L.. The system consists of a network of six controllers, each handling a group of seven antennas. That network was placed below a microcosm tank that recreated important features typical of Nephrops’ grounds, such as the presence of multiple burrows. The animals carried a passive transponder attached to their telson, operating at 13.56 MHz. The tracking system was implemented to concurrently report the behaviour of up to three individuals, in terms of their travelled distances in a specified unit of time and their preferential positioning within the antenna network. To do so, the controllers worked in parallel to send the antenna data to a computer via a USB connection. The tracking accuracy of the system was evaluated by concurrently recording the animals’ behaviour with automated video imaging. During the two experiments, each lasting approximately one week, two different groups of three animals each showed a variable burrow occupancy and a nocturnal displacement under a standard photoperiod regime (12 h light:12 h dark, measured using the RFID method. Similar results were obtained with the video imaging. Our implemented RFID system was therefore capable of efficiently tracking the tested organisms and has a good potential for use on a wide variety of other marine organisms of commercial, aquaculture, and ecological interest.

  18. A new laboratory radio frequency identification (RFID) system for behavioural tracking of marine organisms.

    Science.gov (United States)

    Aguzzi, Jacopo; Sbragaglia, Valerio; Sarriá, David; García, José Antonio; Costa, Corrado; del Río, Joaquín; Mànuel, Antoni; Menesatti, Paolo; Sardà, Francesc

    2011-01-01

    Radio frequency identification (RFID) devices are currently used to quantify several traits of animal behaviour with potential applications for the study of marine organisms. To date, behavioural studies with marine organisms are rare because of the technical difficulty of propagating radio waves within the saltwater medium. We present a novel RFID tracking system to study the burrowing behaviour of a valuable fishery resource, the Norway lobster (Nephrops norvegicus L.). The system consists of a network of six controllers, each handling a group of seven antennas. That network was placed below a microcosm tank that recreated important features typical of Nephrops' grounds, such as the presence of multiple burrows. The animals carried a passive transponder attached to their telson, operating at 13.56 MHz. The tracking system was implemented to concurrently report the behaviour of up to three individuals, in terms of their travelled distances in a specified unit of time and their preferential positioning within the antenna network. To do so, the controllers worked in parallel to send the antenna data to a computer via a USB connection. The tracking accuracy of the system was evaluated by concurrently recording the animals' behaviour with automated video imaging. During the two experiments, each lasting approximately one week, two different groups of three animals each showed a variable burrow occupancy and a nocturnal displacement under a standard photoperiod regime (12 h light:12 h dark), measured using the RFID method. Similar results were obtained with the video imaging. Our implemented RFID system was therefore capable of efficiently tracking the tested organisms and has a good potential for use on a wide variety of other marine organisms of commercial, aquaculture, and ecological interest.

  19. The Serum Complement System: A Simplified Laboratory Exercise to Measure the Activity of an Important Component of the Immune System

    Science.gov (United States)

    Inglis, Jordan E.; Radziwon, Kimberly A.; Maniero, Gregory D.

    2008-01-01

    The immune system is a vital physiological component that affords animals protection from disease and is composed of innate and adaptive mechanisms that rely on cellular and dissolved components. The serum complement system is a series of dissolved proteins that protect against a variety of pathogens. The activity of complement in serum can be…

  20. Laboratory test ordering and results management systems: a qualitative study of safety risks identified by administrators in general practice.

    Science.gov (United States)

    Bowie, Paul; Halley, Lyn; McKay, John

    2014-02-06

    To explore experiences and perceptions of frontline administrators involved in the systems-based management of laboratory test ordering and results handling in general medical practice. Qualitative using focus group interviews. West of Scotland general medical practices in three National Health Service (NHS) territorial board areas. Convenience samples of administrators (receptionists, healthcare assistants and phlebotomists). Transcript data were subjected to content analysis. A total of 40 administrative staff were recruited. Four key themes emerged: (1) system variations and weaknesses (eg, lack of a tracking process is a known risk that needs to be addressed). (2) Doctor to administrator communication (eg, unclear information can lead to emotional impacts and additional workload). (3) Informing patients of test results (eg, levels of anxiety and uncertainty are experienced by administrators influenced by experience and test result outcome) and (4) patient follow-up and confidentiality (eg, maintaining confidentiality in a busy reception area can be challenging). The key findings were explained in terms of sociotechnical systems theory. The study further confirms the safety-related problems associated with results handling systems and adds to our knowledge of the communication and psychosocial issues that can affect the health and well-being of staff and patients alike. However, opportunities exist for practices to identify barriers to safe care, and plan and implement system improvements to accommodate or mitigate the potential for human error in this complex area.

  1. Continuous monitoring of residual chlorine concentrations in response to controlled microbial intrusions in a laboratory-scale distribution system.

    Science.gov (United States)

    Helbling, Damian E; Vanbriesen, Jeanne M

    2008-06-01

    The objective of this work was to evaluate the efficacy of deploying free chlorine sensors as surrogate monitors for bacterial contamination events in drinking water distribution systems. An on-line sensor integral with a laboratory-scale distribution system (LDS) was shown to respond rapidly to changes in residual free chlorine concentrations induced by injected loads of Escherichia coli suspended in a chlorine demand free buffer. The magnitude of the residual response was proportional to the injected cell concentration, the background free chlorine concentration in the LDS, and the contact time between the chlorine residual and the injected suspension, consistent with previous results in batch reactors. The magnitude of the residual response was predicted when kinetic models developed from reaction kinetics between free chlorine and E. coli determined in batch systems were evaluated at contact times determined from LDS hydraulics. This result highlights the suitability of using batch kinetics when modeling contaminant-induced chlorine decay in the distribution system. Modeling the propagation of chlorine demand signals generated by specific pathogens could aid in the assessment of distribution system vulnerability.

  2. A low-cost computer-controlled Arduino-based educational laboratory system for teaching the fundamentals of photovoltaic cells

    Science.gov (United States)

    Zachariadou, K.; Yiasemides, K.; Trougkakos, N.

    2012-11-01

    We present a low-cost, fully computer-controlled, Arduino-based, educational laboratory (SolarInsight) to be used in undergraduate university courses concerned with electrical engineering and physics. The major goal of the system is to provide students with the necessary instrumentation, software tools and methodology in order to learn fundamental concepts of semiconductor physics by exploring the process of an experimental physics inquiry. The system runs under the Windows operating system and is composed of a data acquisition/control board, a power supply and processing boards, sensing elements, a graphical user interface and data analysis software. The data acquisition/control board is based on the Arduino open source electronics prototyping platform. The graphical user interface and communication with the Arduino are developed in C# and C++ programming languages respectively, by using IDE Microsoft Visual Studio 2010 Professional, which is freely available to students. Finally, the data analysis is performed by using the open source, object-oriented framework ROOT. Currently the system supports five teaching activities, each one corresponding to an independent tab in the user interface. SolarInsight has been partially developed in the context of a diploma thesis conducted within the Technological Educational Institute of Piraeus under the co-supervision of the Physics and Electronic Computer Systems departments’ academic staff.

  3. Development of a Real-Time General-Purpose Digital Signal Processing Laboratory System.

    Science.gov (United States)

    1983-12-01

    Hardware Components This section describes the makeup and configuration of the major hardware components needed to support the DSP software system at...requests. .TRUE. = User wants to save reqests. FX = * Frequency response desired for each band in an FIR filter * Used by: PDO05. Changed by: EM...Data items input: ACQIO, DISIO, PROIO, FFTYPE, IMPFIL, LFILT, EDGE, FX , WTX, LGRID. Data items output (changed): RESP. Calling modules: PDATA. Modules

  4. Systems-Level Energy Audit for Main Complex, Construction Engineering Research Laboratory

    Science.gov (United States)

    2003-08-01

    3086 3067 3034 Foam Panel Bldg 1480 1374 1359 TESS Storage 2517 2368 2368 Green House 297 286 286 Total CERL 180897 194558 184145 ERDC/CERL TR-03...2 High Bay – modified bitumen (1999) - Bldg 2 Low Bay – PVC (1984) - Bldg 2 west – APP modified Bitumen (1987) - Bldg 1 far west half – PIB (1989...for other purposes. 3. The environmental chamber located in the foam panel building uses water for cooling. According to UIUC technicians, the system

  5. Conceptual and Laboratory Exercise to Apply Newton's Second Law to a System of Many Forces

    Science.gov (United States)

    Mungan, Carl E.

    2012-01-01

    A pair of objects on an inclined plane are connected together by a string. The upper object is then connected to a fixed post via a spring. The situation is first analysed as a classroom exercise in using free-body diagrams to solve Newton's second law for a system of objects upon which many different kinds of force are acting (string tension,…

  6. [Tooth color matching systems and communication with dental laboratory in indirect restorations: 2011 update].

    Science.gov (United States)

    Ginzburg, M; Gilboa, I

    2012-01-01

    There has been many technological developments in the last decade. Today's shade-matching technologies have been developed in an effort to increase the success of color matching, communication, reproduction and verification in clinical dentistry and, ultimately, to increase the efficiency of esthetic restorative work within any practice. In general, the output of the color measurements can be classified and specified in several ways. The most common systems for describing color are Munsell's System and the international Commission on Illumination (CIE) L a b color system. Albert Munsell described color as a three-dimensional phenomenon. He described the three dimensions as hue, value (brightness), and chroma (saturation). Visual colour determination by comparison of teeth and shade guides is the most frequently applied method in dentistry. Vitapan Classical (Vita Zahnfabrik, Germany) and its derivations(evidence-based Vitapan 3D-Master shade guide and Linearguide) are the most commonly used shade guides. However, several factors can influence consistency of visual colour selection and specification: individual colour matching ability may vary, the colour perception of any individual may show temporal variation, the range of shades available is inadequate and does not cover the complete colour space of natural teeth, the shade guide tabs are not systematically distributed in their colour space, and changes in lighting conditions can cause alterations in perceived colour. instruments for clinical shade-matching encompass spectrophotometers, colorimeters and digital imaging systems. It can be concluded that different devices have different accuracy and precision. Colorimeters are significantly less reliable than spectrophotometers and digital cameras. Benefits and limitations exist, and the clinician must consider how the technology relates to expectations and needs. Combination of visual colour determination (Vitapan 3D-Master shade guide and Linearguide) with

  7. Time Domain Radar Laboratory Operating System Development and Transient EM Analysis.

    Science.gov (United States)

    1981-09-01

    sonopole Pulse Response All receiving antennas are coupled to the Signal Processing Group through a coaxial end-coupling fitted through the imaging plane...The Operating System has been correspondingly 97 written in this language. However, BASIC as used by the GS has been extended to fit the language to...DPO service request. Flag P7 (indicates whether the acquired data is destined for use in Time Domain or Prony Methods) is set to 0 (Time Domain) in

  8. A Structured Light-based System for Scanning Subcutaneous Tumors in Laboratory Animals

    OpenAIRE

    Girit, Ibrahim Cem; Jure-Kunkel, Maria; McIntyre, Kim W

    2008-01-01

    Tumor size or volume is often the primary endpoint in preclinical efficacy studies of anticancer drugs. Efficient and accurate measurement of such tumors is crucial to rapid evaluation of novel drug candidates. Currently available techniques for acquiring high-throughput data on tumor volume are time-consuming and prone to various inaccuracies and errors. The laser-scanning technology we describe here provides a convenient, high-throughput system for tumor measurement that reduces interoperat...

  9. An Experimental Framework for Generating Evolvable Chemical Systems in the Laboratory

    Science.gov (United States)

    Baum, David A.; Vetsigian, Kalin

    2017-12-01

    Most experimental work on the origin of life has focused on either characterizing the chemical synthesis of particular biochemicals and their precursors or on designing simple chemical systems that manifest life-like properties such as self-propagation or adaptive evolution. Here we propose a new class of experiments, analogous to artificial ecosystem selection, where we select for spontaneously forming self-propagating chemical assemblages in the lab and then seek evidence of a response to that selection as a key indicator that life-like chemical systems have arisen. Since surfaces and surface metabolism likely played an important role in the origin of life, a key experimental challenge is to find conditions that foster nucleation and spread of chemical consortia on surfaces. We propose high-throughput screening of a diverse set of conditions in order to identify combinations of "food," energy sources, and mineral surfaces that foster the emergence of surface-associated chemical consortia that are capable of adaptive evolution. Identification of such systems would greatly advance our understanding of the emergence of self-propagating entities and the onset of adaptive evolution during the origin of life.

  10. Laboratory evaluation of the 3-bowl system used for washing-up eating utensils in the field.

    Science.gov (United States)

    Hargreaves, Joanna S

    2006-01-01

    A 3-bowl system is used for washing-up eating utensils on many expeditions when running water is not available. The utensils are washed in the first bowl until they are visibly clean, rinsed in the second bowl, and disinfected in the third bowl. The objective of this study was to evaluate the efficacy of this system in reducing bacterial loads on contaminated utensils and to compare it with alternative washing-up methods. Different washing-up systems were tested with a simulated dish washing of 5 contaminated mess tins followed by 5 uncontaminated mess tins. Porridge was used to simulate food residue and was mixed with Escherichia coli to produce bacterial contamination. Reduction of bacterial load on the mess tins was measured, as were subjective observations regarding the various systems. Bacterial load on contaminated tins is reduced when the 3-bowl system is used. Uncontaminated tins become contaminated in bowl 1, but this is then reduced in subsequent bowls. Disinfectant use, especially bleach, produced a marked reduction in bacterial load on contaminated and uncontaminated tins when used in bowl 2. Detergent is needed to remove grease, and a final rinse removes the smell of disinfectant. Overall, the most effective washing-up system in the laboratory was removal of most food residue with detergent in bowl 1, finish washing with bleach until visibly clean in bowl 2, and a final rinse in drinkable water in bowl 3. This system has advantages over the established 3-bowl system by getting mess tins clean more easily, killing potentially harmful bacteria, and removing the smell and taste of disinfectant.

  11. Effect of two abrasive systems on resin bonding to laboratory-processed indirect resin composite restorations.

    Science.gov (United States)

    Bouschlicher, M R; Cobb, D S; Vargas, M A

    1999-01-01

    This study compared two methods of surface roughening or preparation, with or without the use of proprietary surface wetting agents, to evaluate their effect on resin cement adhesion to the following laboratory-processed, indirect restorations: Artglass (AG), belleGlass HP (BG), Concept (C), and Targis (T). Methods of surface roughening or preparation included microetching with aluminum oxide (AO): 50 microns at 34 psi and silanized silica coating, CoJet-Sand (CJ): 30 microns at 34 psi. Artglass and Concept were tested with and without the use of their respective surface wetting agents: Artglass Liquid (AGL) and Special Bond II (SB). One hundred twenty specimens, each consisting of a pair of cylinders (7.0 x 3 mm and 4.3 x 3 mm) were fabricated. The larger cylinder or base was embedded in self-curing resin in a phenolic ring, and bonding surfaces were finished with 320-grit silicon carbide paper. Specimen pairs for each restorative material were randomly assigned to treatment groups (n = 10) and received the following surface treatments prior to cementation: group 1 (AG/AO/+AGL), group 2 (AG/AO/-AGL), group 3 (AG/CJ/+AGL), group 4 (AG/CJ/-AGL), group 5 (BG/AO), group 6 (BG/CJ), group 7 (C/AO/+SB), group 8 (C/AO/-SB), group 9 (C/CJ/+SB), group 10 (C/CJ/-SB), group 11 (T/AO), and group 12 (T/CJ). Specimen pairs were cemented with a dual-cure resin cement (Dual) and a standardized force of 1 MPa. Specimens were light-cured 40 seconds per side (80 s total), then thermocycled 300 times at between 5 degrees and 55 degrees C. Shear bond strengths (MPa) were determined using a Zwick Materials Testing Machine at a crosshead speed of 5 mm per minute. One-way analysis of variance (ANOVA) and Duncan's multiple range test (alpha = 0.05) by restoration type indicated no significant differences in shear bond strength between BG group 5 (29.8 +/- 5.8), BG group 6 (28.3 +/- 4.3), T group 11 (29.3 +/- 4.9), and T group 12 (29.0 +/- 4.4). Shear bond strength in AG group 3 (35.9 +/- 3

  12. A population laboratory for studying disease processes and mortality--the Demographic Surveillance System, Matlab Comilla, Bangladesh.

    Science.gov (United States)

    D'souza, S

    1981-01-01

    Describes the Demograhic Surveillance System (DSS) of the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), initiated in 1963. The DSS consists of periodic censuses of the study population with intervening registration of vital events. The surveillance area currently consists of 159 villages, containing an estimated population (1974) of 160 thousand, in Matlab, Comilla district. Immediate objectives are assessment of maternal and child health and family planning services in the area, research related to diarrheal diseases, measurements and determinants of fertility and mortality, and development of a demographic field site for training of people involved in national programs. Data are collected through a 3 tiered system: vital events are recorded by female village workers, whose work is checked by field assistants, then coded and processed in Dacca, and put on computer. Selected results from DSS studies are discussed, focusing on particular aspects of mortality or morbidity and epidemiological studies regarding diarrhea and nutrition, to illustrate the possibilities of a population laboratory in these contexts. The DSS has 7 advantages: 1) enables an accurate count of the population; 2) provides accurate sampling frames; 3) provides precise age data; 4) enables studies of client cooperation with health services; 5) facilitates prospective research designs; 6) collects demographic data which may reflect national statistics; 7) serves as a field training site. However, limitations of expense, data collected on causes of events, error correction, and study design must be considered. Computerization should make it possible to turn the DSS into a registration system. Population laboratories in other parts of the world, with differing focuses, are briefly described, and some of their studies are compared to those of the DSS.

  13. Handling Large and Complex Data in a Photovoltaic Research Institution Using a Custom Laboratory Information Management System

    Energy Technology Data Exchange (ETDEWEB)

    White, Robert R.; Munch, Kristin

    2014-01-01

    Twenty-five years ago the desktop computer started becoming ubiquitous in the scientific lab. Researchers were delighted with its ability to both control instrumentation and acquire data on a single system, but they were not completely satisfied. There were often gaps in knowledge that they thought might be gained if they just had more data and they could get the data faster. Computer technology has evolved in keeping with Moore’s Law meeting those desires; however those improvements have of late become both a boon and bane for researchers. Computers are now capable of producing high speed data streams containing terabytes of information; capabilities that evolved faster than envisioned last century. Software to handle large scientific data sets has not kept up. How much information might be lost through accidental mismanagement or how many discoveries are missed through data overload are now vital questions. An important new task in most scientific disciplines involves developing methods to address those issues and to create the software that can handle large data sets with an eye towards scalability. This software must create archived, indexed, and searchable data from heterogeneous instrumentation for the implementation of a strong data-driven materials development strategy. At the National Center for Photovoltaics in the National Renewable Energy Laboratory, we began development a few years ago on a Laboratory Information Management System (LIMS) designed to handle lab-wide scientific data acquisition, management, processing and mining needs for physics and materials science data, and with a specific focus towards future scalability for new equipment or research focuses. We will present the decisions, processes, and problems we went through while building our LIMS system for materials research, its current operational state and our steps for future development.

  14. A guide for the laboratory information management system (LIMS) for light stable isotopes--Versions 7 and 8

    Science.gov (United States)

    Coplen, Tyler B.

    2000-01-01

    The reliability and accuracy of isotopic data can be improved by utilizing database software to (i) store information about samples, (ii) store the results of mass spectrometric isotope-ratio analyses of samples, (iii) calculate analytical results using standardized algorithms stored in a database, (iv) normalize stable isotopic data to international scales using isotopic reference materials, and (v) generate multi-sheet paper templates for convenient sample loading of automated mass-spectrometer sample preparation manifolds. Such a database program, the Laboratory Information Management System (LIMS) for Light Stable Isotopes, is presented herein. Major benefits of this system include (i) a dramatic improvement in quality assurance, (ii) an increase in laboratory efficiency, (iii) a reduction in workload due to the elimination or reduction of retyping of data by laboratory personnel, and (iv) a decrease in errors in data reported to sample submitters. Such a database provides a complete record of when and how often laboratory reference materials have been analyzed and provides a record of what correction factors have been used through time. It provides an audit trail for laboratories. LIMS for Light Stable Isotopes is available for both Microsoft Office 97 Professional and Microsoft Office 2000 Professional as versions 7 and 8, respectively. Both source code (mdb file) and precompiled executable files (mde) are available. Numerous improvements have been made for continuous flow isotopic analysis in this version (specifically 7.13 for Microsoft Access 97 and 8.13 for Microsoft Access 2000). It is much easier to import isotopic results from Finnigan ISODAT worksheets, even worksheets on which corrections for amount of sample (linearity corrections) have been added. The capability to determine blank corrections using isotope mass balance from analyses of elemental analyzer samples has been added. It is now possible to calculate and apply drift corrections to isotopic

  15. Individually ventilated cages impose cold stress on laboratory mice: a source of systemic experimental variability.

    Science.gov (United States)

    David, John M; Knowles, Scott; Lamkin, Donald M; Stout, David B

    2013-11-01

    Individual ventilated cages (IVC) are increasing in popularity. Although mice avoid IVC in preference testing, they show no aversion when provided additional nesting material or the cage is not ventilated. Given the high ventilation rate in IVC, we developed 3 hypotheses: that mice housed in IVC experience more cold stress than do mice housed in static cages; that IVC-induced cold stress affects the results of experiments using mice; and that, when provided shelters, mice behaviorally thermoregulate and thereby rescue the cold-stress effects of IVC. To test these hypotheses, we housed mice in IVC, IVC with shelters, and static cages maintained at 20 to 21 °C. We quantified the cold stress of each housing system on mice by assessing nonshivering thermogenesis and brown adipose vacuolation. To test housing effects in a common, murine model of human disease, we implanted mice with subcutaneous epidermoid carcinoma cells and quantified tumor growth, tumor metabolism, and adrenal weight. Mice housed in IVC had histologic signs of cold stress and significantly higher nonshivering thermogenesis, smaller subcutaneous tumors, lower tumor metabolism, and larger adrenal weights than did mice in static cages. Shelters rescued IVC-induced nonshivering thermogenesis, adrenal enlargement, and phenotype-dependent cold-mediated histologic changes in brown adipose tissue and tumor size. IVC impose chronic cold stress on mice, alter experimental results, and are a source of systemic confounders throughout rodent-dependent research. Allowing mice to exhibit behavioral thermoregulation through seeking shelter markedly rescues the experiment-altering effects of housing-imposed cold stress, improves physiologic uniformity, and increases experimental reproducibility across housing systems.

  16. Idaho National Laboratory Supervisory Control and Data Acquisition Intrusion Detection System (SCADA IDS)

    Energy Technology Data Exchange (ETDEWEB)

    Jared Verba; Michael Milvich

    2008-05-01

    Current Intrusion Detection System (IDS) technology is not suited to be widely deployed inside a Supervisory, Control and Data Acquisition (SCADA) environment. Anomaly- and signature-based IDS technologies have developed methods to cover information technology-based networks activity and protocols effectively. However, these IDS technologies do not include the fine protocol granularity required to ensure network security inside an environment with weak protocols lacking authentication and encryption. By implementing a more specific and more intelligent packet inspection mechanism, tailored traffic flow analysis, and unique packet tampering detection, IDS technology developed specifically for SCADA environments can be deployed with confidence in detecting malicious activity.

  17. Stable and optimal fuzzy control of a laboratory Antilock Braking System

    DEFF Research Database (Denmark)

    Precup, Radu-Emil; Spataru, Sergiu; Petriu, Emil M.

    2010-01-01

    of the rules using the domains of the input variables, and doing the local linearization of the plant model. The original T-S FCs are designed by parallel distributed compensation to obtain the state feedback gain matrices in the consequents of the rules. Two T-S FCs are tuned by imposing relaxed stability...... conditions to the fuzzy control systems (FCSs) and the other two T-S FCs are tuned by the linear-quadratic regulator approach applied to each rule. Linear matrix inequalities are solved to guarantee the global stability of the FCSs. Real-time experimental results validate the original T-S FCs and design...

  18. A structured light-based system for scanning subcutaneous tumors in laboratory animals.

    Science.gov (United States)

    Girit, Ibrahim Cem; Jure-Kunkel, Maria; McIntyre, Kim W

    2008-06-01

    Tumor size or volume is often the primary endpoint in preclinical efficacy studies of anticancer drugs. Efficient and accurate measurement of such tumors is crucial to rapid evaluation of novel drug candidates. Currently available techniques for acquiring high-throughput data on tumor volume are time-consuming and prone to various inaccuracies and errors. The laser-scanning technology we describe here provides a convenient, high-throughput system for tumor measurement that reduces interoperator variability and bias while providing automated data collection, processing and analysis.

  19. Options Impacting the Electric System of the Future (ESF); NREL (National Renewable Energy Laboratory)

    Energy Technology Data Exchange (ETDEWEB)

    Cory, Karlynn

    2015-08-10

    As utilities are faced with adapting to new technologies, technology and policy due diligence are necessary to ensure the development of a future grid that brings greater value to utilities and their consumers. This presentation explores the different kinds of future directions the power industry could consider to create, discussing key components necessary for success. It will also discuss the practical application and possible strategies for utilities and innovators to implement smart technologies that will enable an ultimate ‘intelligent’ grid capable of two-way communication, interoperability, and greater efficiency and system resiliency.

  20. Machinery safety of lathe machine using SHARP-systemic human action reliability procedure: a pilot case study in academic laboratory

    Science.gov (United States)

    Suryoputro, M. R.; Sari, A. D.; Sugarindra, M.; Arifin, R.

    2017-12-01

    This research aimed to understand the human reliability analysis, to find the SHARP method with its functionality on case study and also emphasize the practice in Lathe machine, continued with identifying improvement that could be made to the existing safety system. SHARP comprises of 7 stages including definition, screening, breakdown, representation, impact assessment, quantification and documentation. These steps were combined and analysed using HIRA, FTA and FMEA. HIRA analysed the lathe at academic laboratory showed the level of the highest risk with a score of 9 for the activities of power transmission parts and a score of 6 for activities which shall mean the moving parts required to take action to reduce the level of risk. Hence, the highest RPN values obtained in the power transmission activities with a value of 18 in the power transmission and then the activities of moving parts is 12 and the activities of the operating point of 8. Thus, this activity has the highest risk of workplace accidents in the operation. On the academic laboratory the improvement made on the engineering control initially with a machine guarding and completed with necessary administrative controls (SOP, work permit, training and routine cleaning) and dedicated PPEs.