WorldWideScience

Sample records for san pedro viii

  1. San Pedro River Aquifer Binational Report

    Science.gov (United States)

    Callegary, James B.; Minjárez Sosa, Ismael; Tapia Villaseñor, Elia María; dos Santos, Placido; Monreal Saavedra, Rogelio; Grijalva Noriega, Franciso Javier; Huth, A. K.; Gray, Floyd; Scott, C. A.; Megdal, Sharon; Oroz Ramos, L. A.; Rangel Medina, Miguel; Leenhouts, James M.

    2016-01-01

    The United States and Mexico share waters in a number of hydrological basins and aquifers that cross the international boundary. Both countries recognize that, in a region of scarce water resources and expanding populations, a greater scientific understanding of these aquifer systems would be beneficial. In light of this, the Mexican and U.S. Principal Engineers of the International Boundary and Water Commission (IBWC) signed the “Joint Report of the Principal Engineers Regarding the Joint Cooperative Process United States-Mexico for the Transboundary Aquifer Assessment Program" on August 19, 2009 (IBWC-CILA, 2009). This IBWC “Joint Report” serves as the framework for U.S.-Mexico coordination and dialogue to implement transboundary aquifer studies. The document clarifies several details about the program such as background, roles, responsibilities, funding, relevance of the international water treaties, and the use of information collected or compiled as part of the program. In the document, it was agreed by the parties involved, which included the IBWC, the Mexican National Water Commission (CONAGUA), the U.S. Geological Survey (USGS), and the Universities of Arizona and Sonora, to study two priority binational aquifers, one in the San Pedro River basin and the other in the Santa Cruz River basin. This report focuses on the Binational San Pedro Basin (BSPB). Reasons for the focus on and interest in this aquifer include the fact that it is shared by the two countries, that the San Pedro River has an elevated ecological value because of the riparian ecosystem that it sustains, and that water resources are needed to sustain the river, existing communities, and continued development. This study describes the aquifer’s characteristics in its binational context; however, most of the scientific work has been undertaken for many years by each country without full knowledge of the conditions on the other side of the border. The general objective of this study is to

  2. San Pedro Martir Telescope: Mexican design endeavor

    Science.gov (United States)

    Toledo-Ramirez, Gengis K.; Bringas-Rico, Vicente; Reyes, Noe; Uribe, Jorge; Lopez, Aldo; Tovar, Carlos; Caballero, Xochitl; Del-Llano, Luis; Martinez, Cesar; Macias, Eduardo; Lee, William; Carramiñana, Alberto; Richer, Michael; González, Jesús; Sanchez, Beatriz; Lucero, Diana; Manuel, Rogelio; Segura, Jose; Rubio, Saul; Gonzalez, German; Hernandez, Obed; García, Mary; Lazaro, Jose; Rosales-Ortega, Fabian; Herrera, Joel; Sierra, Gerardo; Serrano, Hazael

    2016-08-01

    The Telescopio San Pedro Martir (TSPM) is a new ground-based optical telescope project, with a 6.5 meters honeycomb primary mirror, to be built in the Observatorio Astronomico Nacional on the Sierra San Pedro Martir (OAN-SPM) located in Baja California, Mexico. The OAN-SPM has an altitude of 2830 meters above sea level; it is among the best location for astronomical observation in the world. It is located 1830 m higher than the atmospheric inversion layer with 70% of photometric nights, 80% of spectroscopic nights and a sky brightness up to 22 mag/arcsec2. The TSPM will be suitable for general science projects intended to improve the knowledge of the universe established on the Official Mexican Program for Science, Technology and Innovation 2014-2018. The telescope efforts are headed by two Mexican institutions in name of the Mexican astronomical community: the Universidad Nacional Autonoma de Mexico and the Instituto Nacional de Astrofisica, Optica y Electronica. The telescope has been financially supported mainly by the Consejo Nacional de Ciencia y Tecnologia (CONACYT). It is under development by Mexican scientists and engineers from the Center for Engineering and Industrial Development. This development is supported by a Mexican-American scientific cooperation, through a partnership with the University of Arizona (UA), and the Smithsonian Astrophysical Observatory (SAO). M3 Engineering and Technology Corporation in charge of enclosure and building design. The TSPM will be designed to allow flexibility and possible upgrades in order to maximize resources. Its optical and mechanical designs are based upon those of the Magellan and MMT telescopes. The TSPM primary mirror and its cell will be provided by the INAOE and UA. The telescope will be optimized from the near ultraviolet to the near infrared wavelength range (0.35-2.5 m), but will allow observations up to 26μm. The TSPM will initially offer a f/5 Cassegrain focal station. Later, four folded Cassegrain and

  3. Hydrology of the middle San Pedro area, southeastern Arizona

    Science.gov (United States)

    Cordova, Jeffrey T.; Dickinson, Jesse E.; Beisner, Kimberly R.; Hopkins, Candice B.; Kennedy, Jeffrey R.; Pool, Donald R.; Glenn, Edward P.; Nagler, Pamela L.; Thomas, Blakemore E.

    2015-05-05

    In the middle San Pedro Watershed in southeastern Arizona, groundwater is the primary source of water supply for municipal, domestic, industrial, and agricultural use. The watershed comprises two smaller subareas, the Benson subarea and the Narrows-Redington subarea. Early 21st century projections for heavy population growth in the watershed have not yet become a reality, but increased groundwater withdrawals could have undesired consequences—such as decreased base flow to the San Pedro River, and groundwater-level declines—that would lead to the need to deepen existing wells. This report describes the hydrology, hydrochemistry, water quality, and development of a groundwater budget for the middle San Pedro Watershed, focusing primarily on the elements of groundwater movement that could be most useful for the development of a groundwater model

  4. Lowland riparian herpetofaunas: the San Pedro River in southeastern Arizona

    Science.gov (United States)

    Philip C. Rosen

    2005-01-01

    Previous work has shown that southeastern Arizona has a characteristic, high diversity lowland riparian herpetofauna with 62-68 or more species along major stream corridors, and 46-54 species in shorter reaches within single biomes, based on intensive fieldwork and museum record surveys. The San Pedro River supports this characteristic herpetofauna, at least some of...

  5. Seafloor geology and benthic habitats, San Pedro Shelf, southern California

    Science.gov (United States)

    Wong, Florence L.; Dartnell, Peter; Edwards, Brian D.; Phillips, Eleyne L.

    2012-01-01

    Seafloor samples, videography, still photography, and real-time descriptions of geologic and biologic constituents at or near the seafloor of the San Pedro Shelf, southern California, advance the study of natural and man-made processes on this coastal area off the metropolitan Los Angeles area. Multibeam echo-sounder data collected by the U.S. Geological Survey in 1998 and 1999 guided sampling and camera work in 2004 resulting in a new seafloor character map that shows possible benthic habitats in much higher resolution (4- and 16-m pixels) than previously available. The seafloor is characterized by primarily muddy sand and sand with outcrops of Miocene and Pliocene bedrock along the Palos Verdes Fault Zone. Observed benthic populations indicate low abiotic complexity, low biotic complexity, and low biotic coverage. The data are provided for use in geographic information systems (GIS).

  6. Geologic and bathymetric reconnaissance overview of the San Pedro shelf region, southern California

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This report presents a series of maps that describe the bathymetry and late Quaternary geology of the San Pedro shelf area as interpreted from seismic-reflection...

  7. SAN PEDRO MARTIR OPTICAL IMAGING OF 9P/TEMPEL 1 V1.0

    Data.gov (United States)

    National Aeronautics and Space Administration — The presented dataset represents 4 half-nights of observing at San Pedro Martir, Baja, Mexico. The target, Comet 9P/Tempel 1, was impacted by the Deep Impact...

  8. Las hermanas de los pobres de San Pedro Claver

    Directory of Open Access Journals (Sweden)

    Rafael Méndez Buendía

    1982-01-01

    Full Text Available "El ser humano actúa, siente y se desenvuelve siempre de acuerdo con lo que él imagina ser verdad acerca de sí mismo y del ambiente que le rodea". Esta es la ley básica del pensamiento humano y este es el modo de que estamos hechos ya que la imaginación desempeña en nuestras vidas un papel mucho más importante de lo que nos podemos imaginar. Extraña al parecer la manera de iniciar este ensayo monográfico de una ilustre congregación religiosa que nace en Barranquilla, "la puerta de oro de Colombia" y "la sultana de los pies desnudos", allá por febrero de 1912, bajo el título de "Hermanas de los Pobres de San Pedro Claver", nombre sugerido a la fundadora por el obispo de Cartagena, monseñor Brioschi, para honrar en forma tal, según sus palabras, al "modelo de virtudes religiosas y al gran apóstol de la caridad cristiana".

  9. [Mescaline and the San Pedro cactus ritual: archaeological and ethnographic evidence in northern Peru].

    Science.gov (United States)

    Carod-Artal, F J; Vázquez-Cabrera, C B

    The San Pedro cactus contains the alkaloid mescaline and other derivates of phenethylamine with hallucinogenic properties. This cactus was used throughout history by a number of different pre-Columbine cultures and civilisations that settled in northern Peru. In this article we review the ethno-archaeological and ethno-historical evidence of the ritual use of the San Pedro cactus in the pre-Columbine cultures, and these findings are compared with the information provided by current ethnographical studies. The longer a cactus has been stored, the stronger and the higher its content in mescaline-derived alkaloids will be. Archaeological evidence has been found of the use of San Pedro for magical-religious purposes in the following pre-Columbine cultures: Cupisnique (1500 BC), Chavin (1000 BC), Moche (100-750 AD) and Lambayeque (750-1350 AD). Today's master shamans use San Pedro on altars ('mesas') erected for healing rites in order to treat enchantment and bad luck. The mesa follows a sophisticated ritual: 'levantar' (raise) or sniff tobacco with alcohol, ingest San Pedro, pinpoint the diseases, cleanse the evil and 'florecer' (flourish) the sick person. The mesa rite is performed in the early hours of Tuesdays and Fridays, which are sacred days in the Andean religions. San Pedro is sometimes replaced by an infusion of plants and seeds that contain hallucinogenic components, such as ayahuasca and the 'mishas' (Brugmansia sp.). The ancient tradition of using the San Pedro cactus for healing and hallucinogenic purposes has remained part of the culture in Andean shamanism up to the present day.

  10. Hydrogeologic framework of the middle San Pedro watershed, southeastern Arizona

    Science.gov (United States)

    Dickinson, Jesse E.; Kennedy, Jeffrey R.; Pool, D.R.; Cordova, Jeffrey T.; Parker, John T.; Macy, J.P.; Thomas, Blakemore

    2010-01-01

    Water managers in rural Arizona are under increasing pressure to provide sustainable supplies of water despite rapid population growth and demands for environmental protection. This report describes the results of a study of the hydrogeologic framework of the middle San Pedro watershed. The components of this report include: (1) a description of the geologic setting and depositional history of basin fill sediments that form the primary aquifer system, (2) updated bedrock altitudes underlying basin fill sediments calculated using a subsurface density model of gravity data, (3) delineation of hydrogeologic units in the basin fill using lithologic descriptions in driller's logs and models of airborne electrical resistivity data, (4) a digital three-dimensional (3D) hydrogeologic framework model (HFM) that represents spatial extents and thicknesses of the hydrogeologic units (HGUs), and (5) description of the hydrologic properties of the HGUs. The lithologic interpretations based on geophysical data and unit thickness and extent of the HGUs included in the HFM define potential configurations of hydraulic zones and parameters that can be incorporated in groundwater-flow models. The hydrogeologic framework comprises permeable and impermeable stratigraphic units: (1) bedrock, (2) sedimentary rocks predating basin-and-range deformation, (3) lower basin fill, (4) upper basin fill, and (5) stream alluvium. The bedrock unit includes Proterozoic to Cretaceous crystalline rocks, sedimentary rocks, and limestone that are relatively impermeable and poor aquifers, except for saturated portions of limestone. The pre-basin-and-range sediments underlie the lower basin fill but are relatively impermeable owing to cementation. However, they may be an important water-bearing unit where fractured. Alluvium of the lower basin fill, the main water-bearing unit, was deposited in the structural trough between the uplifted ridges of bedrock and (or) pre-basin-and-range sediments. Alluvium of

  11. Determination of toxicity levels in the San Pedro River Watershed, Aguascalientes, Mexico.

    Science.gov (United States)

    Santos-Medrano, Gustavo Emilio; Ramírez-López, Elsa Marcela; Hernández-Flores, Saraí; Azuara-Medina, Paulina Margarita; Rico-Martínez, Roberto

    2007-08-01

    A quantitative study of toxicity levels of the San Pedro River and its main tributaries around the city of Aguascalientes, Mexico was conducted. Our study determined individual CL(50) values for each sampling point at 3 different times of the year corresponding to the main seasons of the year in terms of the hydrological cycle (dry, low rain and high rain season). Those LC(50) values were used to calculate the acute. Toxicity Units (aTU) that allowed us to compare levels of toxicity along the San Pedro River and two of its main tributaries. The sample that showed highest toxicity was IPIVA. This is due to the large quantity of industrial discharges that receives. Its effluent was responsible for the largest contribution of toxicity to the San Pedro River over the three rounds of sampling of this study. Our study classified an important portion of the San Pedro River and two of its main tributaries in toxic, moderately toxic and lightly toxic. No portion of the river studied was free of toxicity, either acute or sublethal. This study demonstrated that in spite of the operation of several water treatment plants along the San Pedro River, for the most part, the water quality of the river is still unacceptable.

  12. Geologic and bayhymetric reconnaissance overview of the San Pedro Shelf Region, southern California

    Science.gov (United States)

    Wolf, Stephen C.; Gutmacher, Christina E.

    2004-01-01

    This report presents a series of maps that describe the bathymetry and late Quaternary geology of the San Pedro shelf area as interpreted from seismic-reflection profiles and 3.5-kHz and multibeam bathymetric data. Some of the seismic-reflection profiles were collected with Uniboom and 120-kJ sparker during surveys conducted by the U.S. Geological Survey (USGS) in 1973 (K-2-73-SC), 1978 (S-2-78-SC), and 1979 (S-2a-79-SC). The remaining seismic-reflection profiles were collected in 2000 using Geopulse boomer and minisparker during USGS cruise A-1-00-SC. The report consists of seven oversized sheets: 1. Map of 1978 and 1979 uniboom seismic-reflection and 3.5-kHz tracklines used to map faults and folds on San Pedro Shelf. 2. Maps of multibeam shaded bathymetric relief with faults and folds, and bathymetric contours. 3. Isopach map of unconsolidated sediment, seismic-reflection profile across the San Pedro shelf, seismic-reflection profile across San Gabriel paleo-valley. 4. Seismic-reflection profiles across the Palos Verdes Fault Zone. 5. Geologic map and samples of Uniboom and 120-kJ sparker seismic-reflection profiles used to make the map. 6. Map showing thickness of uppermost (Holocene?) sediment layer. 7. Map of San Gabriel Canyon paleo-valley and associated drainage basins.

  13. Hydrological conditions and evaluation of sustainable groundwater use in the Sierra Vista Subwatershed, Upper San Pedro Basin, southeastern Arizona

    Science.gov (United States)

    Gungle, Bruce; Callegary, James B.; Paretti, Nicholas V.; Kennedy, Jeffrey R.; Eastoe, Christopher J.; Turner, Dale S.; Dickinson, Jesse E.; Levick, Lainie R.; Sugg, Zachary P.

    2016-08-18

    This study assessed progress toward achieving sustainable groundwater use in the Sierra Vista Subwatershed of the Upper San Pedro Basin, Arizona, through evaluation of 14 indicators of sustainable use. Sustainable use of groundwater in the Sierra Vista Subwatershed requires, at a minimum, a stable rate of groundwater discharge to, and thus base flow in, the San Pedro River. Many of the 14 indicators are therefore related to long-term or short-term effects on base flow and provide us with a means to evaluate groundwater discharge to and base flow in the San Pedro River. The indicators were based primarily on 10 to 20 years of data monitoring in the subwatershed, ending in 2012, and included subwatershedwide indicators, riparian-system indicators, San Pedro River indicators, and springs indicators.

  14. Consecuencias del divorcio en niños y adolescentes en San Pedro Sula, Honduras

    Directory of Open Access Journals (Sweden)

    Pedronel González Rodríguez

    2017-03-01

    Full Text Available La presente investigación cuantitativa con enfoque descriptivo, detalla las consecuencias del divorcio en niños y adolescentes desde la perspectiva de los adultos, en la ciudad de San Pedro Sula, Cortes, Honduras. La investigación es parte de una encuesta respondida por 423 personas que residen en San Pedro Sula, quienes conocían el caso de un niño o joven cuyos padres se habían divorciado. Los encuestados refirieron que las consecuencias observadas en los niños o los adolescentes después del divorcio se manifestaron a nivel conductual, afectivo/sentimental, somático, interpersonal, cognitivo, nuevo estilo de vida, académico, económico, uso de servicios de salud mental y desarrollo de síndromes post divorcio.

  15. San Pedro de la Mata (Sonseca, Toledo. Building and decorating an early medieval stone church

    Directory of Open Access Journals (Sweden)

    Mª de los Ángeles Utrero Agudo

    2016-11-01

    Full Text Available This work aims to offer those results obtained by means of the archaeological, stylistic and geological analysis of the church of San Pedro de La Mata, of its building and decorative materials and of its quarries. Combining these studies (and methodologies has made possible to identify the original form of the church, to pinpoint the origin of the materials and to characterize thus the skills of the workshops responsible for its construction and decoration.

  16. Quaternary Geochronology, Paleontology, and Archaeology of the Upper San Pedro River Valley, Sonora, Mexico

    Science.gov (United States)

    Gaines, E. P.

    2013-12-01

    This poster presents the results of multi-disciplinary investigations of the preservation and extent of Quaternary fossil-bearing strata in the San Pedro River Valley in Sonora, Mexico. Geologic deposits in the portions of the San Pedro Valley in southern Arizona contain one of the best late Cenozoic fossil records known in North America and the best record of early humans and extinct mammals on the continent. The basin in the U.S. is one of the type locations for the Blancan Land Mammal Age. Hemiphilian and Irvingtonian fossils are common. Rancholabrean remains are widespread. Strata in the valley adjacent to the international border with Mexico have yielded the densest concentration of archaeological mammoth-kill sites known in the western hemisphere. Despite more than 60 years of research in the U.S., however, and the fact that over one third of the San Pedro River lies south of the international boundary, little has been known about the late Cenozoic geology of the valley in Mexico. The study reported here utilized extensive field survey, archaeological documentation, paleontological excavations, stratigraphic mapping and alluvial geochronology to determine the nature and extent of Quaternary fossil-bearing deposits in the portions of the San Pedro Valley in Sonora, Mexico. The results demonstrate that the Plio-Pleistocene fossil -bearing formations known from the valley in Arizona extend into the uppermost reaches of the valley in Mexico. Several new fossil sites were discovered that yielded the remains of Camelids, Equus, Mammuthus, and other Proboscidean species. Late Pleistocene archaeological remains were found on the surface of the surrounding uplands. AMS radiocarbon dating demonstrates the widespread preservation of middle- to late- Holocene deposits. However, the late Pleistocene deposits that contain the archaeological mammoth-kill sites in Arizona are absent in the valley in Mexico, and are now known to be restricted to relatively small portions of

  17. Sociedades agrícolas en resistencia. Los pueblos de San Miguel, Santa Cruz y San Pedro, 1878-1883

    Directory of Open Access Journals (Sweden)

    Porfirio Neri Guarneros

    2013-09-01

    Full Text Available Agricultural societies in the state of Mexico involved a form of legal resistance used by indigenous communities in the face of liberal individualization policies of communal property, particularly the federal seizure law of June 25, 1956. In this context, some residents of the towns of Santa Cruz and San Miguel created an agricultural association, as did residents from the town of San Pedro, to retain the collective use of their communal goods and acquire some legal capacity. This condition thus allowed indigenous peoples to present writs of amparo to defend "private" rights.

  18. The BOOTES-5 telescope at San Pedro Martir National Astronomical Observatory, Mexico

    Science.gov (United States)

    Hiriart, D.; Valdez, J.; Martínez, B.; García, B.; Cordova, A.; Colorado, E.; Guisa, G.; Ochoa, J. L.; Nuñez, J. M.; Ceseña, U.; Cunniffe, R.; Murphy, D.; Lee, W.; Park, Il H.; Castro-Tirado, A. J.

    2016-12-01

    BOOTES-5 is the fifth robotic observatory of the international network of robotic telescopes BOOTES (Burst Observer and Optical Transient Exploring Optical System). It is located at the National Astronomical Observatory at Sierra San Pedro Martir, Baja California, Mexico. It was dedicated on November 26, 2015 and it is in the process of testing. Its main scientific objective is the observation and monitoring of the optic counterparts of gamma-ray bursts as quickly as possible once they have been detected from space or other ground-based observatories. BOOTES-5 fue nombrado Telescopio Javier Gorosabel en memoria del astrónomo español Javier Gorosabel Urkia.

  19. El modelo Cure Violence: reducción de la violencia en San Pedro Sula (Honduras)

    OpenAIRE

    Ransford, Charles; Brent Decker, R.; Cruz, Guadalupe M.; Sánchez, Francisco; Slutkin, Gary

    2017-01-01

    Desarrollado en Estados Unidos, el modelo Cure Violence («Curar la Violencia») es un programa de control epidémico que reduce la violencia a través de cambios de normas y de comportamiento. Este artículo revisa, en primer lugar, la situación de violencia en Honduras y, en particular, en San Pedro Sula que, durante años, fue la ciudad con mayores tasas de homicidios del mundo. Para hacer frente a esta situación, en 2013 comenzó a implementarse en algunas zonas de la ciudad una adaptación del p...

  20. Environmental evidence of fossil fuel pollution in Laguna Chica de San Pedro lake sediments (Central Chile)

    Energy Technology Data Exchange (ETDEWEB)

    Chirinos, L. [Centro de Ciencias Ambientales EULA-Chile, Universidad de Concepcion, PO Box 160-C, Concepcion (Chile)]. E-mail: lchirin@pucp.edu.pe; Rose, N.L. [Environmental Change Research Centre, University College London, 26 Bedford Way, London WG1HOAP (United Kingdom); Urrutia, R. [Centro de Ciencias Ambientales EULA-Chile, Universidad de Concepcion, PO Box 160-C, Concepcion (Chile); Munoz, P. [Departamento de Biologia Marina, Universidad Catolica del Norte, Larrondo 1281, Coquimbo (Chile); Torrejon, F. [Centro de Ciencias Ambientales EULA-Chile, Universidad de Concepcion, PO Box 160-C, Concepcion (Chile); Torres, L. [Departamento de Botanica, Universidad de Concepcion, Concepcion (Chile); Cruces, F. [Departamento de Botanica, Universidad de Concepcion, Concepcion (Chile); Araneda, A. [Centro de Ciencias Ambientales EULA-Chile, Universidad de Concepcion, PO Box 160-C, Concepcion (Chile); Zaror, C. [Facultad de Ingenieria Quimica, Universidad de Concepcion, Concepcion (Chile)

    2006-05-15

    This paper describes lake sediment spheroidal carbonaceous particle (SCP) profiles from Laguna Chica San Pedro, located in the Biobio Region, Chile (36{sup o} 51' S, 73{sup o} 05' W). The earliest presence of SCPs was found at 16 cm depth, corresponding to the 1915-1937 period, at the very onset of industrial activities in the study area. No SCPs were found at lower depths. SCP concentrations in Laguna Chica San Pedro lake sediments were directly related to local industrial activities. Moreover, no SCPs were found in Galletue lake (38{sup o} 41' S, 71{sup o} 17.5' W), a pristine high mountain water body used here as a reference site, suggesting that contribution from long distance atmospheric transport could be neglected, unlike published data from remote Northern Hemisphere lakes. These results are the first SCP sediment profiles from Chile, showing a direct relationship with fossil fuel consumption in the region. Cores were dated using the {sup 21}Pb technique. - The lake sediment record of SCPs shows the record of fossil-fuel derived pollution in Central Chile.

  1. La restauración en comunidad de la iglesia de San Pedro de Atacama

    Directory of Open Access Journals (Sweden)

    Beatriz Yuste Miguel

    2017-12-01

    Full Text Available En medio del gran desierto de Atacama caracterizado por una gran aridez y amplitud térmica, se ubica en un fértil oasis, la iglesia de San Pedro de Atacama. Su construcción original dataría del siglo XVI, la actual, del siglo XVIII, conserva el estilo arquitectónico barroco del ámbito sur andino. La obra está sorprendentemente adecuada a la ecología, sismicidad y materialidad del desierto. Destacan sus muros de adobe, techumbre de par y nudillo de chañar y entablado de cactus. La iglesia ha sufrido sucesivos incendios, sismos, inundaciones y sobrecargas en el techo que han ido provocando daños acumulativos graves en su estructura. El proyecto de restauración ejecutado por Fundación Altiplano buscó ajustarse a los criterios y técnicas vigentes para la conservación patrimonial de construcciones en tierra, como también a los de preservación del patrimonio y desarrollo sostenible, a través del fortalecimiento de la comunidad de San Pedro de Atacama.

  2. Submarine landslides of San Pedro Escarpment, southwest of Long Beach, California

    Science.gov (United States)

    Bohannon, R.G.; Gardner, J.V.

    2004-01-01

    The coastal infrastructure of the southern greater Los Angeles metropolitan area would be profoundly affected by a large tsunami. Submarine slope failures and active faults, either of which could have generated a tsunami, are known on the shelf and slope near Long Beach. Large slope failures are present on the San Pedro Escarpment and on the basin slope adjacent to the San Pedro shelf. The southeastern part of the escarpment has had a long history of slope failure. The most recent failure, the Palos Verdes slide, is over 4.5 km long, has been dated as 7500 years old, and involved over 0.34 km 3 of material, which now litters the adjacent basin floor. Other, smaller, deposits from nearby failures are also present, as are buried wedges of debris that indicate slope failures have occurred locally throughout the Holocene and much of the late Pleistocene. Slope failures have occurred in response to continual Quaternary uplift of the Palos Verdes anticlinorium. The Palos Verdes slide could potentially have generated a failure-related tsunami with an amplitude in the range of 8-12 m because it apparently failed catastrophically, started in shallow water, evolved on low-drag bedding planes, had a long slide path, and involved high-strength lithified material. ?? 2003 Elsevier B.V. All rights reserved.

  3. San Pedro leucogranite from A Coruña, Northwest of Spain: Uses of a heritage stone.

    Science.gov (United States)

    Freire Lista, David Martin; Fort, Rafael

    2016-04-01

    Place names often provide examples of the importance that a heritage stone has had with the foundation of cities and throughout its subsequent history. The heritage of a town is related to its geological environment, which provides its construction materials. The historic quarry of San Pedro leucogranite in northwest Spain is considered here and its petrological characteristics, utilization throughout history and its heritage value are evaluated. The Romans used this stone, however there was an initial boom in the use of San Pedro leucogranite for Galician Romanesque sculptures during the Middle Ages. Notable among other monuments such as the twelfth century Romanesque churches of Santa María del Campo and Santiago and it has also been used to build the pedestal of Herculeś Tower, this is a majestic lighthouse in A Coruña city, it was declared World Heritage by UNESCO in 2 009. San Pedro leucogranite is part of the pavement of the main tourist streets of A Coruña city (Calle Real and Cantones, to name some of the most popular). Betanzos is a historical village about 25 km from A Coruña, its historical center was declared historic-artistic site in 1970. The Betanzos historical center also provides major utilization of this stone in sculptures and ashlars of San Francisco and Santa María de Azogue churches, among others. Color, rarity, appearance, quality and durability are the primary characteristics that have led to San Pedro leucogranite being used for sculpting and building. These characteristics and historical quarrying should be assessed with respect to its heritage significance and strategic location near the city of A Coruña. The preservation and enhancement of its historic quarries that are essential for conservation work and restoration of heritage assets built with the San Pedro leucogranite in this region.

  4. Violencia rural intercomunitaria no sueste de Galicia. Un caso concreto: Moialde contra San Pedro de Pousada

    Directory of Open Access Journals (Sweden)

    Alonso Gayoso, Emilio

    2015-12-01

    Full Text Available The objective of this work is make an approximation to the research about the rural violence across the analysis of the conflict between two villages in the southeast of Galicia (Santa Maria de Moialde and San Pedro de Pousada, by economic and social causes, means of a cualitative research and the interview of several witness, with the design to determinate the most probable causes of the conflict between the communities, in economic and social nature. With the obtained dates, we reach to the conclusion that the most part of the rural conflict in the studied ambit begin in the competition to access to the single women and to the comunal goods, needful to the daily survival.El objetivo de este trabajo es realizar una aproximación al estudio de la violencia rural a través del análisis de los conflictos entre dos aldeas del sudeste de Galicia (Santa María de Moialde y San Pedro de Pousada, tanto por motivos económicos como sociales, mediante una investigación cualitativa y la entrevista de varios testigos, con la intención de determinar las causas más probables de los conflictos entre comunidades, tanto de naturaleza social como económica. A partir de los datos obtenidos se llega a la conclusión de que la mayoría de los conflictos rurales en el ámbito estudiado se originan en la competencia por las mujeres solteras y por el acceso a los bienes comunales, necesarios para la supervivencia cotidiana. [gl] O obxectivo deste traballo é facer unha aproximación ao estudo da violencia rural a través da análise dos conflitos entre dúas aldeas do sueste de Galicia (Santa María de Moialde e San Pedro de Pousada, tanto por motivos económicos como sociais, mediante unha investigación cualitativa e a entrevista de varias testemuñas, coa intención de determinar as causas máis probables dos conflitos entre comunidades, tanto de natureza social como económica. A partir dos datos obtidos chégase á conclusión de que a maioría dos conflitos

  5. Multi-criteria approach to the infrastructural problems of San Pedro de la Paz - From an urbanistic and hydraulic perspective

    NARCIS (Netherlands)

    Crielaard, R.; Keulers, B.; Koudstaal, K.; Kox, S.; Veerman, M.; Vila Santamaria, R.

    2015-01-01

    Part I concerns the analysis of the infrastructural problems at hand in San Pedro de la Paz. To get insight into the problems first an analysis of the location is made. This analysis involves the geographical characteristics of the city, historical development, land use, infrastructure etc. Based

  6. 78 FR 25299 - Notice of Intent To Prepare a Resource Management Plan for the San Pedro Riparian National...

    Science.gov (United States)

    2013-04-30

    ... Service (FIRS) at 1-800-877-8339 to contact the above individual during normal business hours. The FIRS is... receive a reply during normal business hours. SUPPLEMENTARY INFORMATION: This document provides notice... San Pedro River; SPRNCA's designation as a Globally Important Bird Area; Determining which areas...

  7. 77 FR 55268 - Union Pacific Railroad Company-Acquisition and Operation Exemption-San Pedro Railroad Operating...

    Science.gov (United States)

    2012-09-07

    ... on Mack H. Shumate, Jr., Union Pacific Railroad Company, Law Department, 101 North Wacker Drive, Room... Surface Transportation Board Union Pacific Railroad Company--Acquisition and Operation Exemption--San Pedro Railroad Operating Company, LLC Union Pacific Railroad Company (UP) has filed a verified notice of...

  8. A dendrochronology based fire history of Jeffry pine-mixed conifer forests in the Sierra San Pedro Martir, Mexico

    Science.gov (United States)

    Scott L. Stephens; Carl N. Skinner; Samantha J. Gill

    2003-01-01

    Conifer forests in northwestern Mexico have not experienced systematic fire suppression or logging, making them unique in western North America. Fire regimes of Pinus jeffreyi Grev. & Balf. mixed conifer forests in the Sierra San Pedro Martir, Baja California, Mexico, were determined by identifying 105 fire dates from 1034 fire scars in 105 specimens. Fires were...

  9. La explotación industrial de las salinas de San Pedro del Pinatar (Murcia

    Directory of Open Access Journals (Sweden)

    Gustavo A. Ballesteros Pelegrín

    2013-01-01

    Full Text Available La explotación de las Salinas de San Pedro del Pinatar ha experimentado un profundo cambio a lo largo de la historia en sus métodos de producción, procesado y comercialización de la sal, así como en su estructura empresarial. La información obtenida mediante entrevistas a los trabajadores, datos y documentos suministrados por Salinera Española además de una recopilación bibliográfica, permite describir el proceso de obtención de sal, clasificar la sal según sus usos y caracterizar la estabilidad alcanzada en la producción, la comercialización y los principales mercados. Así como, identificar las debilidades y fortalezas que determinan el presente y sus perspectivas de futuro.

  10. La «villa» de San Pedro de Valdanzo (Soria

    Directory of Open Access Journals (Sweden)

    Alfredo JIMENO MARTÍNEZ

    2009-10-01

    Full Text Available Se estudia la «villa» romana de San Pedro de Valdanzo (Soria en su marco ambiental y económico. La excavación permitió detectar un asentamiento rural anterior (S. II-III y descubrir parte de la construcción señorial —dos tramos del corredor, el «oecus» y una segunda estancia—, de los s. IV-V, con mosaicos, en parte quemados y escasos objetos. El estudio integral de las estructuras arquitectónicas y la cultura material se enfoca hacia la interpretación funcional de la zona excavada y a establecer el marco cronológico de este asentamiento. Finalmente se exponen algunas consideraciones sobre las características del poblamiento de los S. IV-V en la zona del Alto Duero.

  11. La fiesta xita: patrimonio biocultural mazahua de San Pedro el Alto, México

    Directory of Open Access Journals (Sweden)

    Alicia Y. Vásquez González

    2016-01-01

    Full Text Available Ante la crisis ambiental y de la modernidad, se propone conservar la riqueza cultural y biológica de la humanidad como patrimonio. Así, se valora y revalora el patrimonio vivo, como es la relación entre culturas y biodiversidad, que se manifiestan en paisajes y territorios de los pueblos originarios. Se propone la fiesta xita (viejos como patrimonio biocultural de la milpa mazahua. El estudio etnográfico se realizó en San Pedro el Alto, México. La fiesta xita es parte del patrimonio biocultural mazahua, mediante la cual se entretejen agrobiodiversidad y cultura, lo que permite que los mazahuas mantengan y desarrollen sus actividades sociales y culturales que han sido heredadas de generación en generación.

  12. MUSEO SANTUARIO DE SAN PEDRO CLAVER: UN ESPACIO EN MEMORIA DEL ESCLAVO DE LOS ESCLAVOS

    Directory of Open Access Journals (Sweden)

    Sandra E. Mendoza Lafaurie

    2011-04-01

    Full Text Available El Museo Santuario San Pedro Claver funciona desde el año 1950 en el claustro de los jesuitas de Cartagena. Este espacio está dedicado a honrar la memoria de este santo, que en la colonia se dedicó a la protección de los miles de esclavos que llegaban a Cartagena de Indias. Este museo cuenta con una colección arqueológica de material precolombino y de la colonia, una de arte religioso de diferentes épocas, así como una colección donada por la familia Zapata Olivella. El objeto del presente artículo es ver la manera en que este museo es un espacio de memoria, así como analizar su funcionamiento y organización.

  13. The Cure Violence model: violence reduction in San Pedro Sula (Honduras

    Directory of Open Access Journals (Sweden)

    Charles Ransford

    2017-09-01

    Full Text Available Developed in the United States, the Cure Violence model is a programme of epidemic control that reduces violence through changes to norms and behaviour. This article primarily examines the issue of violence in Honduras and, in particular, in San Pedro Sula which was for years the city with the highest homicide rates in the world. To tackle this situation, in 2013 an adapted version of the programme began to be implemented in certain areas of the city. After describing the adaptation of the model to the context of the Honduran city, its results are analysed in two periods of 2014 and 2015 (compared to 2013 and 2014, respectively: a significant reduction in shootings and a minor fall in the homicide figures stand out.

  14. Study of plaster finishes on San Pedro de los Francos church at Calatayud

    Directory of Open Access Journals (Sweden)

    Sánchez de Rojas, Mª I

    2007-06-01

    Full Text Available This study of the plaster finishes on San Pedro de los Francos Church at Calatayud revealed, firstly, the stratigraphic sequence based on the interpretation of the bonding interfaces; and secondly, the evolution of placement techniques from mudéjar style textured and painted false stonework (15th century to the smooth plastering and paint typical of later phases. Finally, scanning electron microscope (SEM, energy dispersive X-ray microanalysis (EDX and X-ray diffraction (XRD studies showed that gypsum and anhydrite are the main components of both binder and aggregate in these mortars. In other words, they constitute traditional multiphase plasters whose coarser particles or aggregate were a byproduct of the artisanal manufacturing process.El estudio de los enlucidos de la iglesia de San Pedro de los Francos de Calatayud ha permitido demostrar, en primer lugar, la secuencia estratigráfica mediante la lectura de la interfase de adherencia; en segundo lugar, la evolución de las técnicas de aplicación, desde el enlucido mudéjar, un fingido de piedra agramilado y pintado (siglo XV, hasta los enlucidos lisos y pinturas aplicados posteriormente. Y, finalmente, a través de los estudios de microscopía electrónica de barrido (SEM, microanálisis por energía dispersiva de rayos X (EDX y de difracción de rayos X (DRX, se ha determinado que son morteros en los que tanto el conglomerante como el árido son yeso y anhidrita, que correspondería a un yeso tradicional multifase, cuyos granos más gruesos analizados como áridos proceden del producto obtenido artesanalmente.

  15. Analysis of Pollution Potential of the Upper San Pedro and Upper Santa Cruz Aquifers

    Science.gov (United States)

    Lincicome, A. D.; Brusseau, M. L.

    2011-12-01

    Transboundary aquifers along the U.S.-Mexico border are subject to unique demands and constraints, and are a focus of priority assessment under the auspices of the Transboundary Aquifer Assessment Program. The Upper Santa Cruz and Upper San Pedro basins in southern Arizona are experiencing rapid population growth and development, and the associated water and environmental resource demands are stressors to water resource sustainability. A groundwater vulnerability assessment was performed to evaluate groundwater resources within these two basins using DRASTIC (Depth to water, net Recharge, Aquifer media, Soil media, Topography, Impact of vadose zone media, and hydraulic Conductivity of the aquifer). DRASTIC analysis is a standardized method developed by the Environmental Protection Agency for evaluating groundwater pollution potential. DRASTIC was used to characterize the potential for contamination of groundwater by land surface sources. Data layers for the DRASTIC analysis were compiled and analyzed separately based on rating methods from DRASTIC. These methods rate each layer on a scale of one to ten, one being the least vulnerable to contamination and ten being the most vulnerable. Weights for each layer were also provided by DRASTIC based on each layer's contribution to the overall vulnerability of the aquifer. These layers were then analyzed using the equation: DRDW+RRRW+ARAw+SRSW+TRTW+IRIW+CRCW = Pollution Potential, where R = rating, and W = weight. This assessment was coupled with current knowledge of groundwater contamination and current land use practices to identify zones of potential concern. This information can be used to better direct city planning, zoning programs, and groundwater monitoring and remediation efforts throughout the Upper Santa Cruz and Upper San Pedro basins.

  16. Infecção por Enterobius vermicularis em populações agro-pastoris pré-colombianas de San Pedro de Atacama, Chile Enterobius vermicularis infection in pre-Columbian population from San Pedro de Atacama, Chile

    Directory of Open Access Journals (Sweden)

    Luiz Fernando Ferreira

    1989-01-01

    Full Text Available Enterobius vermicularis eggs were found in human coprolites collected from the archaeological site of San Pedro de Atacama, North of Chile, in occupational layers dated from 1,000 BC. Agricultures and herding were begining at this period of time in this region of South America. The paleoparasitological data amplifies the knowledge about the distribution of human oxyuriasis in Pre-Columbian America.

  17. Mechanical conceptual design of 6.5 meter telescope: Telescopio San Pedro Mártir (TSPM)

    Science.gov (United States)

    Uribe, Jorge; Bringas, Vicente; Reyes, Noe; Tovar, Carlos; López, Aldo; Caballero, Xóchitl; Martínez, César; Toledo, Gengis; Lee, William; Carramiñana, Alberto; González, Jesús; Richer, Michael; Sánchez, Beatriz; Lucero, Diana; Manuel, Rogelio; Rubio, Saúl; González, Germán.; Hernández, Obed; Segura, José; Macias, Eduardo; García, Mary; Lazaro, José; Rosales, Fabián.; del Llano, Luis

    2016-07-01

    Telescopio San Pedro Mártir (TSPM) project intends to build a 6.5 meters telescope with alt-azimuth design, currently at the conceptual design. The project is an association between Instituto de Astronomía de la Universidad Nacional Autónoma de México (IA-UNAM) and the Instituto Nacional de Astrofísica, Óptica Electrónica (INAOE) in partnership with department of Astronomy and Steward Observatory of University of Arizona and Smithsonian Astrophysical Observatory of Harvard University. Conceptual design of the telescope is lead and developed by the Centro de Ingeniería y Desarrollo Industrial (CIDESI). An overview of the feasibility study and the structural conceptual design are summarized in this paper. The telescope concept is based on telescopes already commissioned such as MMT and the Baade and Clay Magellan telescopes, building up on these proven concepts. The main differences relative to the Magellan pair are; the elevation axis is located 1 meter above the primary mirror vertex, allowing for a similar field of view at the Cassegrain and both Nasmyth focal stations; instead of using a vane ends to position the secondary mirror TSPM considers an Steward platform like MMT; finally TSPM has a larger floor distance to m1 cell than Magellans and MMT. Initially TSPM will operate with an f/5 Cassegrain station, but the design considers further Nasmyth configurations from a Cassegrain f/5 up to a Gregorian f/11. The telescope design includes 7 focal stations: 1 Cassegrain; 2 Nasmyth; and 4 folded-Cassegrain. The telescope will be designed and manufactured in Mexico, will be design in Queretaro by CIDESI and built between Queretaro and Michoacán manufacturing facilities; it will be preassembled in these facilities and disassembled to send it to the San Pedro Mártir Observatory for final integration. The azimuth and altitude structure is planned to be constructed in modules and transported by truck and shipped to Ensenada and finally to the OAN where is going

  18. Using Geochemical Tracers to Quantify Baseflow Inputs to the San Pedro River, Southeast Arizona

    Science.gov (United States)

    Baillie, M. N.; Hogan, J. F.; Ekwurzel, B.; Wahi, A. K.; Eastoe, C. J.

    2005-05-01

    Groundwater managers in the semiarid Southwest U.S. must balance the demands of growing populations against the needs of rare riparian ecosystems. The Upper San Pedro River Basin in Southeastern Arizona provides water for the rapidly growing area of Fort Huachuca, Sierra Vista, and surrounding communities. This basin also supports the riparian area by providing baseflow to the San Pedro River and shallow groundwater to phreatic riparian vegetation. Before water managers can properly plan for sustenance of the riparian area, they require answers about the inputs of baseflow into the river. What is the temporal and spatial variability of recharge and discharge? What are the relative inputs of different sources (i.e. recharge of monsoon runoff and inflow of basin groundwater) into the riparian aquifer? We have used a suite of geochemical tracers to address these questions. Most precipitation in this region falls during the summer monsoons and winter frontal storms. Because these events have different source areas, their respective stable isotopic signatures differ. We use these isotopic compositions as end members in mixing equations in order to determine the dominant season for recharge. Groundwater in the basin has a narrow range of stable isotope compositions, varying from 62 to 72% winter precipitation. The basin isotopic composition is very similar to water in the mountain front and block, indicating that recharge from these areas is the dominant source for basin groundwater. Basin groundwater residence times, determined using the radioactive isotope carbon-14, are on the order of 10,000 years or more, indicating a low recharge rate. In contrast, riparian groundwater has a wide variation of isotopic values, indicating that this water is a mixture of basin groundwater and monsoon runoff, varying from 20 to 90% basin groundwater. The dominance of basin groundwater or monsoon runoff in different areas of the river correlates well with independent classification of

  19. Thermal Performance of Traditional and New Concept Houses in the Ancient Village of San Pedro De Atacama and Surroundings

    Directory of Open Access Journals (Sweden)

    Massimo Palme

    2014-05-01

    Full Text Available Earth, wood and others traditional materials are still used in house constructions in many regions of the world, especially in the Andes. San Pedro de Atacama, for example, is a small town where earth blocks (adobes and rammed earth (tapial are important ways to construct, an art passed on through generations. Energy properties of earth are very interesting: thermal conductivity is low; heat storage capacity is high; color is variable and can be used to absorb or to reject solar radiation. However, nowadays the government social dwelling service is proposing a different type of construction, which does not maintain any relation with the tradition. This paper presents simulation studies and monitoring of four different San Pedro houses, constructed by using different techniques and materials. Results can be used to discuss the thermal performance needed in desert climate and the reliability of social dwelling service houses, under construction at this time in the town.

  20. Fire-scar formation in Jeffrey pine - mixed conifer forests in the Sierra San Pedro Martir, Mexico

    Science.gov (United States)

    Scott L. Stephens; Danny L. Fry; Brandon M. Collins; Carl N. Skinner; Ernesto Franco-Vizcaino; Travis J. Freed

    2010-01-01

    Little is known about the probability of fire-scar formation. In this study, we examined all mixed conifer trees for fire-scar formation in a 16 ha watershed that burned as part of a 2003 wildfire in Sierra San Pedro Ma´rtir National Park (SSPM), Mexico. In addition, we examine the probability of fire-scar formation in relation to the previous fire interval in forests...

  1. Proyecto integral para la conservación del Claustro de San Pedro Claver en Cartagena de Indias

    OpenAIRE

    Téllez Castañeda, Germán; Instituto Carlos Arbeláez Camacho para el Patrimonio Arquitectónico y Urbano, Pontificia Universidad Javeriana

    2014-01-01

    Among the great number of ancient monuments located In Cartagena de Indias - Colombia - the Cloister of San Pedro Claver has an outstanding historic value. The Jesuitic complex consists of two buildings: the XVIIth century cloister, owned by The Company during the colonial period; and the temple built fifty years later, bearing today the advocation of the Saint Guardian of the Slaves. The Jesuits first came to the city in 1604, to found a school. Cartagena was an important trading port...

  2. Lessons for Integrated Water Resources Management from the San Pedro HELP Basin on the U.S.-Mexico Border

    Science.gov (United States)

    Browning, A.; Goodrich, D.; Varady, R.; Richter, H.

    2007-12-01

    The San Pedro Basin sits within an intermountain ecotone with the Sonoran and Chihuahuan Deserts to the west and east and the Rocky Mountain and Sierra Madre Mountain habitats to the north and south. The headwaters of the basin originate in northern Sonora and flow north into southeast Arizona. As the region's only remaining perennial stream, the San Pedro River serves as an international flyway for over 400 bird species. It is one of the western hemisphere's most ecologically diverse areas with some 20 different biotic communities, and "possesses one of the richest assemblages of land mammal species in the world." Large mining, military, and municipal entities are major users of the same groundwater resources that maintain perennial flow in the San Pedro. This presentation describes empirical evidence of the positive impacts on watershed management of scientists and policy researchers working closely with water managers and elected officials in a functioning HELP basin. We posit that when hydrologists help watershed groups understand the processes controlling water quality and quantity, and when managers and stakeholders connect these processes to social, economic and legal issues then transboundary cooperation in policymaking and water management is most effective. The distinctive physical and socioeconomic characteristics of the basin as well as differences in institutional regulations, water law issues, and their local implementations in Arizona and Sonora are discussed. We illustrate how stakeholders and scientific researchers in both countries strive to balance ecosystem needs with human demands to create new, integrated basin management. Finally, we describe how the accomplishments of the San Pedro collaborative process, including the use of environmental-conflict-resolution tools, have contributed to the UNESCO HELP (Hydrology for the Environment, Life, and Policy) agenda.

  3. Evaluation of NDVI to assess avian abundance and richness along the upper San Pedro River

    Science.gov (United States)

    McFarland, T.M.; van Riper, Charles; Johnson, G.E.

    2012-01-01

    Remote-sensing models have become increasingly popular for identifying, characterizing, monitoring, and predicting avian habitat but have largely focused on single bird species. The Normalized Difference Vegetation Index (NDVI) has been shown to positively correlate with avian abundance and richness and has been successfully applied to southwestern riparian systems which are uniquely composed of narrow bands of vegetation in an otherwise dry landscape. Desert riparian ecosystems are important breeding and stopover sites for many bird species but have been degraded due to altered hydrology and land management practices. Here we investigated the use of NDVI, coupled with vegetation, to model the avian community structure along the San Pedro River, Arizona. We also investigated how vegetation and physical features measured locally compared to those data that can be gathered through remote-sensing. We found that NDVI has statistically significant relationships with both avian abundance and species richness, although is better applied at the individual species level. However, the amount of variation explained by even our best models was quite low, suggesting that NDVI habitat models may not presently be an accurate tool for extensive modeling of avian communities. We suggest additional studies in other watersheds to increase our understanding of these bird/NDVI relationships.

  4. EXAMINING LOCAL SOCIAL IDENTITIES THROUGH PATTERNS OF BIOLOGICAL AND CULTURAL VARIATION IN THE SOLCOR AYLLU, SAN PEDRO DE ATACAMA, CHILE / EXAMINANDO LAS IDENTIDADES SOCIALES LOCALES A TRAVÉS DE LOS PATRONES DE VARIACIÓN BIOLÓGICA Y CULTURAL EN EL AYLLU DE SOLCOR, SAN PEDRO DE ATACAMA, CHILE

    National Research Council Canada - National Science Library

    Kristin L. Nado; Sara J. Marsteller; Laura M. King; Blair M. Daverman; Christina Torres-Rouff; Kelly J. Knudson

    2012-01-01

    .... This research explores how local group identities impacted the ways in which individuals and communities at San Pedro de Atacama, Chile, expressed their relationship to the Tiwanaku polity during the Middle Horizon...

  5. Heavy metals in water of the San Pedro River in Chihuahua, Mexico and its potential health risk.

    Science.gov (United States)

    Gutiérrez, Roberto L; Rubio-Arias, Hector; Quintana, Ray; Ortega, Juan Angel; Gutierrez, Melida

    2008-06-01

    The objective of this study was to determine the seasonal and downstream water quality variations of the San Pedro River in Chihuahua, Mexico. Water samples were collected monthly from October 2005 to August 2006 in triplicate, totaling 165 water samples. The five sampling locations were: below the Francisco I. Madero dam (LP); between Rosales and Delicias (RD); Meoqui (M); El Torreon (ET), and Julimes (LJ). The levels of As, Be, Ca, Cd, Co, Cu, Cr, Fe, Li, Mg, Mn, Mo, Ni, Pb, Sb, Se, Sr, Ti, Ta, V and Zn were measured using an Inductively Coupled Plasma- Optical Emission Spectrometry (ICP-OES) Perkin Elmer 2100. In addition, temperature, pH, electrical conductivity and total and fecal coliformes were determined. The statistical analysis considered a factorial treatment design; where factor A was the location point and factor B was sampling date. In addition, a multivariate technique looking for principal components was performed. The results indicated that some samples exceeded Mexican standards for As, Be, Ca, Cd, Co, Cr, Fe, Mn, Ni, Pb, Sb, Se, Sr and Zn. The As level must be considered for a red flag to the communities along the Rio San Pedro because both the monthly average level (0.10 mg L-1) and location (0.10 mg L-1) exceeded the Mexican and International norms. The multivariate analysis showed a predominant aggregation at the LP location, meaning that there was a predominance of As, Sr, Fe and Li. At the rest of the locations the elements did not present a tendency for aggregation. Statistics applied to sampling month showed that December, January, March and April were aggregated in a negative quadrant of component 1 indicating a predominance of V, Ni, Be, Fe and As. Overall, the results confirmed that this stretch of the San Pedro River is contaminated with heavy metals and other contaminants that might affect human health as well as the health of the ecosystem.

  6. Heavy metals in water of the San Pedro River in Chihuahua, Mexico and its potential health risk

    Directory of Open Access Journals (Sweden)

    Melida Gutierrez

    2008-06-01

    Full Text Available The objective of this study was to determine the seasonal and downstream water quality variations of the San Pedro River in Chihuahua, Mexico. Water samples were collected monthly from October 2005 to August 2006 in triplicate, totaling 165 water samples. The five sampling locations were: below the Francisco I. Madero dam (LP; between Rosales and Delicias (RD; Meoqui (M; El Torreon (ET, and Julimes (LJ. The levels of As, Be, Ca, Cd, Co, Cu, Cr, Fe, Li, Mg, Mn, Mo, Ni, Pb, Sb, Se, Sr, Ti, Ta, V and Zn were measured using an Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES Perkin Elmer 2100. In addition, temperature, pH, electrical conductivity and total and fecal coliformes were determined. The statistical analysis considered a factorial treatment design; where factor A was the location point and factor B was sampling date. In addition, a multivariate technique looking for principal components was performed. The results indicated that some samples exceeded Mexican standards for As, Be, Ca, Cd, Co, Cr, Fe, Mn, Ni, Pb, Sb, Se, Sr and Zn. The As level must be considered for a red flag to the communities along the Rio San Pedro because both the monthly average level (0.10 mg L-1 and location (0.10 mg L-1 exceeded the Mexican and International norms. The multivariate analysis showed a predominant aggregation at the LP location, meaning that there was a predominance of As, Sr, Fe and Li. At the rest of the locations the elements did not present a tendency for aggregation. Statistics applied to sampling month showed that December, January, March and April were aggregated in a negative quadrant of component 1 indicating a predominance of V, Ni, Be, Fe and As. Overall, the results confirmed that this stretch of the San Pedro River is contaminated with heavy metals and other contaminants that might affect human health as well as the health of the ecosystem.

  7. El ordenamiento territorial de los barrios indígenas en la parroquia de San Pedro Cholula, Puebla

    OpenAIRE

    Morales Arizmendi, Moisés

    2015-01-01

    Abordaremos el análisis de la Parroquia de San Pedro Cholula, dentro de su diseño urbano, para que nos lleve a explicar cómo dentro de este contexto, se tienen las expresiones arquitectónicas y un diseño territorial que con el paso del tiempo y las relaciones sociales que se realizan, van creando relaciones de identidad. Para este análisis solo es posible lograr una explicación, si se expone la estructura social religiosa de los barrios de Cholula. Sobre esta base de la información es posible...

  8. El hallazgo más austral de un Mammut americanum: el caso del mastodonte de San Pedro Sula, Honduras

    OpenAIRE

    Lucas, Spencer G.; Guillermo E. Alvarado

    2011-01-01

    Un molar derecho M3 de un mastodonte, colectado a principios del presente siglo cerca de San Pedro Sula, al noroeste de Honduras, es clasificado en el presente trabajo como un Mammut americanum, constituyendo el registro más austral hasta el momento de un mastodonte americano. Su presencia en Honduras sugiere una extensión de su habitat en el tipo de bosque norteamericano y agrega, además, otro elemento de origen norteño a la fauna fósilde megamamíferos del Cuaternario de Honduras.  A righ...

  9. Biogeochemical Insights into B-Vitamins in the Coastal Marine Sediments of San Pedro Basin, CA

    Science.gov (United States)

    Monteverde, D.; Berelson, W.; Baronas, J. J.; Sanudo-Wilhelmy, S. A.

    2015-12-01

    Coastal marine sediments support a high abundance of mircoorganisms which play key roles in the cycling of nutrients, trace metals, and carbon, yet little is known about many of the cofactors essential for their growth, such as the B-vitamins. The suite of B-vitamins (B1, B2, B6, B7, B12) are essential across all domains of life for both primary and secondary metabolism. Therefore, studying sediment concentrations of B-vitamins can provide a biochemical link between microbial processes and sediment geochemistry. Here we present B-vitamin pore water concentrations from suboxic sediment cores collected in September 2014 from San Pedro Basin, a silled, low oxygen, ~900 m deep coastal basin in the California Borderlands. We compare the B-vitamin concentrations (measured via LCMS) to a set of geochemical profiles including dissolved Fe (65-160 μM), dissolved Mn (30-300 nM), TCO2, solid phase organic carbon, and δ13C. Our results show high concentrations (0.8-3nM) of biotin (B7), commonly used for CO2 fixation as a cofactor in carboxylase enzymes. Thiamin (B1) concentrations were elevated (20-700nM), consistent with previous pore water measurements showing sediments could be a source of B1 to the ocean. Cobalamin (B12), a cofactor required for methyl transfers in methanogens, was also detected in pore waters (~4-40pM). The flavins (riboflavin [B2] and flavin mononucleotide[FMN]), molecules utilized in external electron transfer, showed a distinct increase with depth (10-90nM). Interestingly, the flavin profiles showed an inverse trend to dissolved Fe (Fe decreases with depth) providing a potential link to culture experiments which have shown extracellular flavin release to be a common trait in some metal reducers. As some of the first B-vitamin measurements made in marine sediments, these results illustrate the complex interaction between the microbial community and surrounding geochemical environment and provide exciting avenues for future research.

  10. Inorganic pigment study of the San Pedro Gonzalez Telmo Sibyls using total reflection X-ray fluorescence

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez, Cristina, E-mail: vazquez@cnea.gov.a [Universidad de Buenos Aires, Facultad de Ingenieria, Paseo Colon 850. C1063ACU, Buenos Aires (Argentina); Comision Nacional de Energia Atomica, Gerencia Quimica, Av. Gral Paz 1499, B1650KNA, San Martin (Argentina); Custo, Graciela, E-mail: custo@cnea.gov.a [Comision Nacional de Energia Atomica, Gerencia Quimica, Av. Gral Paz 1499, B1650KNA, San Martin (Argentina); Barrio, Nestor, E-mail: nbarrio@unsam.edu.a [CEIRCAB-TAREA, Universidad Nacional de San Martin (UNSAM), Escuela de Humanidades, Campus Miguelete, 25 de Mayo y Francia, B1650KNA, San Martin (Argentina); Burucua, Jose, E-mail: gburucua@unsam.edu.a [CEIRCAB-TAREA, Universidad Nacional de San Martin (UNSAM), Escuela de Humanidades, Campus Miguelete, 25 de Mayo y Francia, B1650KNA, San Martin (Argentina); Boeykens, Susana [Universidad de Buenos Aires, Facultad de Ingenieria, Paseo Colon 850. C1063ACU, Buenos Aires (Argentina); Marte, Fernando, E-mail: fmarte@unsam.edu.a [CEIRCAB-TAREA, Universidad Nacional de San Martin (UNSAM), Escuela de Humanidades, Campus Miguelete, 25 de Mayo y Francia, B1650KNA, San Martin (Argentina)

    2010-09-15

    This article describes the study carried out on a series of oil paintings on canvas from the eighteenth century that were restored at Centro de Produccion e Investigacion en Restauracion y Conservacion Artistica y Bibliografica - Tarea (CEIRCAB-Tarea), Buenos Aires, Argentina: the San Pedro Gonzalez Telmo Sibyls. Experimental study was undertaken to identify inorganic pigments and the technique used in their confection; and, in this way, try to add information about their local origin. Therefore special emphasis was put to infer technologies used in the manufacturing of these paintings. Elemental analysis was performed by total reflection X-ray fluorescence spectrometry (TXRF) and complemented by optical and polarized light microscopy. Microsampling was carefully done over areas of the paintings which were damaged and where a small additional loss will not be noticed. This investigation has shown that a variety of pigments were used, namely earth pigments (red and yellow ochres), white lead, vermilion, etc., and they were used either pure or in mixtures. This characterization helped conservators in their decisions regarding a better understanding of the deterioration processes. In addition, this research about the material composition allowed the art historians and restorers the possibility to obtain information about where, when or by whom The San Pedro Gonzalez Telmo Sibyls may have been painted.

  11. Inorganic pigment study of the San Pedro Gonzalez Telmo Sibyls using total reflection X-ray fluorescence

    Science.gov (United States)

    Vázquez, Cristina; Custo, Graciela; Barrio, Néstor; Burucúa, José; Boeykens, Susana; Marte, Fernando

    2010-09-01

    This article describes the study carried out on a series of oil paintings on canvas from the eighteenth century that were restored at Centro de Producción e Investigación en Restauración y Conservación Artística y Bibliográfica - Tarea (CEIRCAB-Tarea), Buenos Aires, Argentina: the San Pedro González Telmo Sibyls. Experimental study was undertaken to identify inorganic pigments and the technique used in their confection; and, in this way, try to add information about their local origin. Therefore special emphasis was put to infer technologies used in the manufacturing of these paintings. Elemental analysis was performed by total reflection X-ray fluorescence spectrometry (TXRF) and complemented by optical and polarized light microscopy. Microsampling was carefully done over areas of the paintings which were damaged and where a small additional loss will not be noticed. This investigation has shown that a variety of pigments were used, namely earth pigments (red and yellow ochres), white lead, vermilion, etc., and they were used either pure or in mixtures. This characterization helped conservators in their decisions regarding a better understanding of the deterioration processes. In addition, this research about the material composition allowed the art historians and restorers the possibility to obtain information about where, when or by whom The San Pedro González Telmo Sibyls may have been painted.

  12. Factores biológicos y socio-familiares en el adulto mayor con depresión en San Pedro del Cebollar-Cuenca 2015-2016

    OpenAIRE

    Suquilanda Heredia, José Andrés

    2017-01-01

    Objetivo: Determinar los factores biológicos, socio-familiares en el adulto mayor con depresión en San Pedro del Cebollar – Cuenca período 2015-2016. Material y métodos: Se realizó un estudio cuantitativo, analítico y transversal, con 126 adultos mayores que acudieron al Subcentro de San Pedro del Cebollar – Cuenca período 2015-2016. Se aplicó un instrumento de recolección de datos para conocer las características sociodemográficas y test de Yesavage para determinar depresión, funcionalida...

  13. Estimating Earthquake Hazards in the San Pedro Shelf Region, Southern California

    Science.gov (United States)

    Baher, S.; Fuis, G.; Normark, W. R.; Sliter, R.

    2003-12-01

    The San Pedro Shelf (SPS) region of the inner California Borderland offshore southern California poses a significant seismic hazard to the contiguous Los Angeles Area, as a consequence of late Cenozoic compressional reactivation of mid-Cenozoic extensional faults. The extent of the hazard, however, is poorly understood because of the complexity of fault geometries and uncertainties in earthquake locations. The major faults in the region include the Palos Verdes, THUMS Huntington Beach and the Newport-Inglewood fault zones. We report here the analysis and interpretation of wide-angle seismic-reflection and refraction data recorded as part of the Los Angeles Region Seismic Experiment line 1 (LARSE 1), multichannel seismic (MCS) reflection data obtained by the USGS (1998-2000) and industry borehole stratigraphy. The onshore-offshore velocity model, which is based on forward modeling of the refracted P-wave arrival times, is used to depth migrate the LARSE 1 section. Borehole stratigraphy allows correlation of the onshore and offshore velocity models because state regulations prevent collection of deep-penetration acoustic data nearshore (within 3 mi.). Our refraction study is an extension of ten Brink et al., 2000 tomographic inversion of LARSE I data. They found high velocities (> 6 km/sec) at about ~3.5 km depth from the Catalina Fault (CF) to the SPS. We find these velocities, shallower (around 2 km depth) beneath the Catalina Ridge (CR) and SPS, but at a depth 2.5-3.0 km elsewhere in the study region. This change in velocity structure can provide additional constraints for the tectonic processes of this region. The structural horizons observed in the LARSE 1 reflection data are tied to adjacent MCS lines. We find localized folding and faulting at depth (~2 km) southwest of the CR and on the SPS slope. Quasi-laminar beds, possible of pelagic origin follow the contours of earlier folded (wavelength ~1 km) and faulted Cenozoic sedimentary and volcanic rocks. Depth to

  14. Minisparker seismic-reflection data of field activity S-5-09-SC: San Pedro Basin, offshore southern California from 2009-07-06 to 2009-07-10

    Science.gov (United States)

    Sliter, Ray W.; Conrad, James E.; Ryan, Holly F; Triezenberg, Peter

    2017-01-01

    This dataset includes raw and processed, high-resolution seismic-reflection data collected in 2009 to explore a possible connection between the San Diego Trough Fault and the San Pedro Basin Fault. The survey is in the San Pedro Basin between Santa Catalina Island and San Pedro, California. The data were collected aboard the U.S. Geological Survey R/V Parke Snavely. The seismic-reflection data were acquired using a SIG 2mille minisparker. Subbottom acoustic penetration spanned tens to several hundreds of meters, variable by location.

  15. Coupling Between the Changes in CO2 Concentration and Sediment Biogeochemistry in the Salinas De San Pedro Mudflat, California, USA

    Science.gov (United States)

    Rezaie Boroon, M.; Diaz, S.; Torres, V.; Lazzaretto, T.; Dehyn, D.

    2013-12-01

    We investigated the effects of elevated carbon dioxide [CO2] on biogeochemistry of marsh sediment including speciation of selected heavy metals in Salinas de San Pedro mudflat in California. The Salinas de San Pedro mudflat has higher carbon (C) content than the vast majority of fully-vegetated salt marshes even with the higher tidal action in the mudflat. Sources for CO2 were identified as atmospheric CO2 as well as due to local fault degassing process. We measured carbon dioxide [CO2], methane [CH4], total organic carbon, dissolved oxygen, salinity, and heavy metal concentration in various salt marsh locations. Overall, our results showed that CO2 concentration ranging from 418.7 to 436.9 [ppm], which are slightly different in various chambers but are in good agreement with some heavy metal concentrations values in mudflat at or around the same location. The selected metal concentration values (ppm) ranging from 0.003 - 0.011(As); 0.001-0.005 (Cd); 0.04-0.02 (Cr); 0.13-0.38 (Cu); 0.11-0.38 (Pb); 0.0009-0.020 (Se); and 0.188-0.321 (Zn). The low dissolved O2 [ppm] in the pore water sediment indicates suboxic environment. Additionally, CO2 [ppm] and loss on ignition (LOI) [%] correlated inversely; the higher CO2 content, the lower was the LOI; that is to say the excess CO2 may caused higher rates of decomposition and therefore it leads to lower soil organic matter (LOI) [%] on the mudflat surface. It appears that the elevated CO2 makes changes in salt marsh pore water chemistry for instance the free ionic metal (Cu2+, Pb2+, etc.) speciation is one of the most reactive form because simply assimilated by the non-decayed or alive organisms in sediment of salt marsh and/or in water. This means that CO2 not only is a sign of improvement in plant productivity, but also activates microbial decomposition through increases in dissolved organic carbon availability. CO2 also increases acidification processes such as anaerobic degradation of microorganism and oxidation of

  16. AN ACCURACY ASSESSMENT OF 1997 LANDSAT THEMATIC MAPPER DERIVED LAND COVER FOR THE UPPER SAN PEDRO WATERSHED (U.S./MEXICO)

    Science.gov (United States)

    High-Resolution airborne color video data were used to evaluate the accuracy of a land cover map of the upper San Pedro River watershed, derived from June 1997 Landsat Thematic Mapper data. The land cover map was interpreted and generated by Instituto del Medio Ambiente y el Bes...

  17. Interactions between western gall rust and its Pinus hosts, P. jeffreyi and P. contorta, in Sierra De San Pedro Martir National Park, Northern Baja California, Mexico

    Science.gov (United States)

    Detlev R. Vogler; Brian W. Geils

    2008-01-01

    The Sierra de San Pedro Martir is a mountain range in north-central Baja that comprises the southern-most extension of the Californian coniferous flora, including Pinus jeffreyi, P. contorta, P. lambertiana, Abies concolor, and Calocedrus decurrens. These forests are similar...

  18. A River Running in the Desert: Lessons for Integrated Water Resources Management from the San Pedro HELP Basin on the U.S.-Mexico Border 1978

    Science.gov (United States)

    Flowing from Mexico into the United States, the San Pedro Basin is the region’s only remaining perennial stream and one of the western hemisphere’s most ecologically diverse areas. Large mining, military, and municipal entities are major users of the same groundwater resources that maintain perennia...

  19. INTERVENCIÓN ARQUEOMAGNÉTICA DEL HORNO DE LA HACIENDA SAN PEDRO CHOLUL (MÉRIDA, YUCATÁN (Archaeomagnetic Dating of a Kiln from the San Pedro Cholul Hacienda (Merida, Yucatan

    Directory of Open Access Journals (Sweden)

    Héctor Hernández Álvarez

    2017-12-01

    Full Text Available En el presente trabajo se reportan los resultados de un estudio arqueomagnético realizado en un horno para la quema de cal encontrado en la hacienda henequenera de San Pedro Cholul, localizada al noroeste de la ciudad de Mérida en el estado de Yucatán, México. La finalidad del estudio es establecer una cronología confiable y analizar las posibles consecuencias sociales, económicas y ambientales de este asentamiento, el cual existió posiblemente desde mediados del siglo XIX hasta los años sesenta del siglo pasado. Para la determinación de la cronología, se utilizó el método de datación arqueomagnética a estructuras pirotecnológicas de estas características. Las muestras estudiadas provienen de rocas y ladrillos del horno y arrojan una edad entre 1835 y 1896, la cual concuerda con la información histórica disponible y se interpreta como el periodo de producción más importante de la región. ENGLISH: This paper presents the results of an archaeomagnetic study carried out on a lime burning kiln at the henequen hacienda of San Pedro Cholul (northwest of the city of Merida in the state of Yucatan, Mexico. The purpose of the study is to establish a reliable chronology and to estimate the possible social, economic and environmental implications of this settlement, which may have existed from the middle of the nineteenth century until the 1960s. Archaeomagnetic dating was carried out on samples obtained from rocks and bricks from the kiln and give an age between 1835 and 1896. This date range agrees with available historical information and is interpreted as the most important production period of the region.

  20. Una inusual iconografía de San Pedro Mártir en una tabla de Juan Correa de Vivar

    Directory of Open Access Journals (Sweden)

    Mateo Gómez, Isabel

    2011-12-01

    Full Text Available This small panel is here attributed to Juan Correa de Vivar, and added to his catalogue of works. Given its dimensions, the painting could have been made for the private devotion of a Dominican friar, who most likely would have suggested to the artist the unusual iconography involving Saint Peter Martyr.

    Se atribuye y suma al catálogo del pintor una pequeña tabla que, por sus dimensiones, pudo ser concebida para cumplir la devoción privada de algún fraile dominico, quien sin duda pudo sugerir al pintor la iconografía inusual representada de San Pedro Mártir

  1. Geodinámica ambiental de La cuenca Del río San Pedro. Flanco norandino venezolano

    Directory of Open Access Journals (Sweden)

    Kati A. MONTIEL

    2001-12-01

    Full Text Available El estúdio abarca el perímetro de Ia cuenca del rio San Pedro, flanco norandino venezolano, donde amplias áreas deforestadas, cicatrices de deslizamiento, sistemas de diaclasas, cercavas y surcos se conjugan y generan un desequilíbrio morfogenético expresado en movimientos de masa generalizados y avalanchas torrenciales, representando un peligro natural para Ia población local. Mediante el diserto de un SIG se efectuo una matriz espacial sustentada en el análisis geológico, geomorfológico, geotécnico, fotointerpretativo y ajustado a Ia clasificación de Ferrer, se identificaron diferentes niveles de estabilidad relativa: inestabilidad, inestabilidad crítica y potencialmente inestable, estos localizados en los espacios de mayor concentración poblacional.

  2. Elaboración y consumo de tortillas como patrimonio cultural de San Pedro del Rosal, México

    Directory of Open Access Journals (Sweden)

    María Cristina Chávez Mejía

    2017-07-01

    Full Text Available Planting and consumption of maize are identity and determining activities in the evolution of population’s food heritage, since they contribute to food security and preservation of the biocultural heritage. Based on qualitative collection of information from producers and consumers of hand-made maize tortillas in San Pedro del Rosal, Atlacomulco, Estado de Mexico, an ethnographic study was conducted. From an anthropological perspective, the production of tortillas was characterized in order to analyze the know-how concerning this food, typical of central Mexico’s culinary identity. For tortilla producers, the know-how constitutes an identity heritage, as well as possibly a strategy for generating an income. In the case of consumers, it was concluded that they choose hand-made tortillas given their symbolic value.

  3. Assessment of goods and valuation of ecosystem services (AGAVES) San Pedro River Basin, United States and Mexico

    Science.gov (United States)

    Semmens, Darius; Kepner, William; Goodrich, David

    2010-01-01

    A consortium of federal, academic, and nongovernment organization (NGO) partners have established a collaborative research enterprise in the San Pedro River Basin to develop methods, standards, and tools to assess and value ecosystem goods and services. The central premise of ecosystem services research is that human condition is intrinsically linked to the environment. Human health and well-being (including economic prosperity) depend on important supporting, regulating, provisioning, and cultural services that we derive from our surrounding ecosystems. The AGAVES project is intended as a demonstration study for incorporating ecosystem services information into resource management policy and decisionmaking. Accordingly, a nested, multiscale project design has been adopted to address a range of stakeholder information requirements. This design will further facilitate an evaluation of how well methods developed in this project can be transferred to other areas.

  4. Ictiofauna de los humedales del río San Pedro, Balancán, Tabasco, México

    Directory of Open Access Journals (Sweden)

    Alfonso Castillo-Domínguez

    2011-06-01

    Full Text Available Los humedales de San Pedro sostienen redes tróficas del sistema fluvial debido a la alta disponibilidad de hábitats y a sus variaciones espacio-temporales. En esta investigación se estudió la composición, densidad y biomasa de la ictiofauna de los humedales; se capturaron 1 049 organismos de 25 especies, dos son exóticas: Oreochromis niloticus y Parachromis managuense. Con 23 especies capturadas en el sitio I, 17 en el II y 14 en el III. En la época de secas se obtuvo mayor riqueza con 21 especies, lluvias con 17 y cinco en nortes. La mayor densidad se mostró en el sitio II (0.23ind./m², seguido de los sitios I y III (0.12, 0.12ind./m². La mayor biomasa fue en secas (8.30g/m², seguida de lluvias (2.1g/m² y por último nortes (0.01g/m². La mayor densidad se mostró en secas (0.43ind./m² y la mínima en nortes (0.023ind./m². Las especies dominantes en densidad según el diagrama Olmstead-Tukey fueron: Petenia splendida, Vieja heterospila, Vieja synspila, Dorosoma petenense y Astyanax aeneus. Por lo tanto, existieron diferencias significativas en los parámetros ecológicos y ambientales. Al considerar la variación en la riqueza podemos concluir que los humedales del río San Pedro, es un sistema donde la composición de la ictiofauna responde a las fluctuaciones espaciales y temporales.

  5. Using in-situ Glider Data to Improve the Interpretation of Time-Series Data in the San Pedro Channel

    Science.gov (United States)

    Teel, E.; Liu, X.; Seegers, B. N.; Ragan, M. A.; Jones, B. H.; Levine, N. M.

    2016-02-01

    Oceanic time-series have provided insight into biological, physical, and chemical processes and how these processes change over time. However, time-series data collected near coastal zones have not been used as broadly because of regional features that may prevent extrapolation of local results. Though these sites are inherently more affected by local processes, broadening the application of coastal data is crucial for improved modeling of processes such as total carbon drawdown and the development of oxygen minimum zones. Slocum gliders were deployed off the coast of Los Angeles from February to July of 2013 and 2014 providing high temporal and spatial resolution data of the San Pedro Channel (SPC), which includes the San Pedro Ocean Time Series (SPOT). The data were collapsed onto a standardized grid and primary and secondary characteristics of glider profiles were analyzed by principal component analysis to determine the processes impacting SPC and SPOT. The data fell into four categories: active upwelling, offshore intrusion, subsurface bloom, and surface bloom. Waters across the SPC were most similar to offshore water masses, even during the upwelling season when near-shore blooms are commonly observed. The SPOT site was found to be representative of the SPC 86% of the time, suggesting that the findings from SPOT are applicable for the entire SPC. Subsurface blooms were common in both years with co-located chlorophyll and particle maxima, and results suggested that these subsurface blooms contribute significantly to the local primary production. Satellite estimation of integrated chlorophyll was poor, possibly due to the prevalence of subsurface blooms and shallow optical depths during surface blooms. These results indicate that high resolution in-situ glider deployments can be used to determine the spatial domain of coastal time-series data, allowing for broader application of these datasets and greater integration into modeling efforts.

  6. Post-Palaeolithic - Palaeolithic pictorial sequences in the Sierra de San Pedro. International Tagus. Cáceres

    Directory of Open Access Journals (Sweden)

    Bueno Ramírez, Primitiva

    2010-06-01

    Full Text Available The UAH team is developing successive projects of heritage evaluation in the International Tagus, focused on the megalithic culture. Our surveys, based on the theoretical statement of a predictive model that considers the presence of outdoor paintings, make the Sierra de San Pedro one of the most important schematic painting groups of the Iberian Peninsula. Its parallel development to the sites with outdoor engravings in the International Tagus draws a complex set of symbols with a major role in the definition of megalithic territories. The identification of Palaeolithic figures coincides with similar recurrences documented in outdoor sites of the western peninsula, pointing to the resort to the past as one of the arguments of vindication and use of traditional territories.

    El equipo de la UAH viene desarrollando sucesivos proyectos de valoración patrimonial en el Tajo Internacional centrados en la cultura megalítica. Nuestras prospecciones a partir de la exposición teórica de un modelo predictivo que considera la presencia de pinturas al aire libre, hacen de la Sierra de San Pedro uno de los más importantes conjuntos de la pintura esquemática de la Península Ibérica. Su desarrollo paralelo a los yacimientos con grabados al aire libre del Tajo Internacional dibuja un complejo entramado de símbolos con un importante papel en la definición de los territorios megalíticos. La identificación de figuras paleolíticas coincide con recurrencias similares documentadas en los yacimientos al aire libre del occidente peninsular, apuntando al recurso al pasado como uno de los argumentos de reivindicación y uso de territorios tradicionales.

  7. Procesos históricos y ambientales en Cerro de San Pedro, San Luis Potosí, México, 1948-1997

    Directory of Open Access Journals (Sweden)

    Paula Andrea Martínez Chaves

    2010-01-01

    Full Text Available Los estudios sobre el municipio Cerro de San Pedro enfatizan la continuidad ambiental aparente que estimula la minería; sin embargo, esta lectura subvalora otras dinámicas que ocurren en la zona. Con base en observaciones directas de trabajo en campo, para realizar análisis de coberturas vegetales, entrevistas con los habitantes de la zona, revisión de cartografía e investigación de archivo, el presente trabajo muestra procesos como la explotación de recursos vegetales y el pastoreo, como actividades económicas paralelas a las labores mineras, y que no habían sido tratados hasta ahora.

  8. Ictiofauna de los humedales del río San Pedro, Balancán, Tabasco, México

    Directory of Open Access Journals (Sweden)

    Alfonso Castillo-Domínguez

    2011-06-01

    Full Text Available Los humedales de San Pedro sostienen redes tróficas del sistema fluvial debido a la alta disponibilidad de hábitats y a sus variaciones espacio-temporales. En esta investigación se estudió la composición, densidad y biomasa de la ictiofauna de los humedales; se capturaron 1 049 organismos de 25 especies, dos son exóticas: Oreochromis niloticus y Parachromis managuense. Con 23 especies capturadas en el sitio I, 17 en el II y 14 en el III. En la época de secas se obtuvo mayor riqueza con 21 especies, lluvias con 17 y cinco en nortes. La mayor densidad se mostró en el sitio II (0.23ind./m², seguido de los sitios I y III (0.12, 0.12ind./m². La mayor biomasa fue en secas (8.30g/m², seguida de lluvias (2.1g/m² y por último nortes (0.01g/m². La mayor densidad se mostró en secas (0.43ind./m² y la mínima en nortes (0.023ind./m². Las especies dominantes en densidad según el diagrama Olmstead-Tukey fueron: Petenia splendida, Vieja heterospila, Vieja synspila, Dorosoma petenense y Astyanax aeneus. Por lo tanto, existieron diferencias significativas en los parámetros ecológicos y ambientales. Al considerar la variación en la riqueza podemos concluir que los humedales del río San Pedro, es un sistema donde la composición de la ictiofauna responde a las fluctuaciones espaciales y temporales.Ichthyofauna from wetlands of San Pedro, Balancán, Tabasco, México. San Pedro River’s wetlands sustain trophic nets in the fluvial system, due to the high habitat availability, and space and temporal variations. In order to describe the relationship between environmental parameters and ichthyofauna, this study evaluated fish assemblages composition, distribution, abundance, density, biomass, richness species, diversity and equitability in the wetlands. Sampling considered three different sites and climatic seasons (dry, rainy and cold fronts. The physical and chemical parameters considered were dissolved oxygen, temperature, pH, water

  9. El tumbo de San Pedro de Montes como instrumento de recreación de la memoria institucional = The Cartulary of San Pedro de Montes as a Tool for Reconstructing Institutional Memory

    Directory of Open Access Journals (Sweden)

    Leticia Agúndez San Miguel

    2016-06-01

    Full Text Available Este artículo pretende indagar en las lógicas de producción del cartulario conocido como Tumbo de San Pedro de Montes para valorar su aportación como instrumento de recreación de la memoria institucional de este monasterio leonés. El análisis de las diferentes estrategias de selección y clasificación que guiaron la arquitectura de este códice diplomático constituye el método principal para la consecución de este propósito. Así, la identificación de los diferentes parámetros memoriales que articulan el discurso historiográfico propuesto en sus folios nos advierte de la existencia de diferentes etapas de recreación de la memoria monástica, de sus tiempos de referencia y de su utilidad variable para los propósitos proyectados con la confección de este cartulario. Un resultado que evidencia la necesaria atención de los investigadores a la materialidad del cartulario para el adecuado aprovechamiento de su contenido.This article aims to explore the logic of production of the cartulary known as the Tumbo of San Pedro de Montes in order to assess its contribution as an instrument for the reconstruction of the institutional memory of this monastery in the kingdom of Leon. The methodology used for this task consists of an analysis of the strategies of selection and classification that stablished the structure of this diplomatic codex. This will allow us to identify the different memory parameters that construct the historiographical discourse present within it. Hence, we can gauge the existence of various stages in the reconstruction of the monastery’s memory, of its time frame and of the various uses of the cartulary’s projected purpose. This study confirms the importance of the material dimension of this cartulary for the adequate use of its content by researchers.

  10. Etnoarqueoloxia e Microhistoria dunha paisaxe cultural: a parroquia de San Pedro de Cereixa (Pobra de Brollón, Lugo

    Directory of Open Access Journals (Sweden)

    Ayán Vila, Xurxo M.

    2005-12-01

    Full Text Available From the point of view of Landscape Archaeology we try to show the genealogy and development of a cultural landscape in a galician little village. Our research définies several spatial patterns built by the different societies which inhabited the area of San Pedro de Cereixa from the Recent Prehistory to nowdays. In the second part of our research we get inside the mental universe of the traditional peasant community who endowed this landscape with sense. This cosmovision is not a static model but a cultural product of a historical process that embraces a mixture of continuities and ruptures, popular believes and the imposition of a official religion and a civilization of customs by the Church

    [gl] Este artigo recolle a análise arqueohistórica do proceso de conformación dunha paisaxe cultural a escala local, como é a parroquia de S. Pedro de Cereixa (Pobra de Brollón, Lugo. Partindo da Arqueoloxía da Paisaxe reconstruímo-las diferentes estratexias de construcción do espacio social empregadas polas sucesivas formacións socioculturais que ocuparon a zona dende a Prehistoria Recente deica a actualidade. Na segunda parte achegámonos ó patrón de racionalidade manexado pola comunidade campesina que construíu e dotou de sentido á paisaxe rural tradicional. Para acadar este obxectivo, desenvolvemos unha aproximación interdisciplinar coa angueira de maximizar tanto as aportacións de diferentes tendencias historiográficas (Historia Rural, Antropoloxía Histórica, Microhistoria como a potencialidade da utilización conxunta de diversas ferramentas metodolóxicas, nomeadamente o baldeirado de fontes documentais secundarias, a enquisa etnográfica, a análise iconográfica e a Historia Oral.

  11. Restauración del Tajo de San Pedro en La Alhambra de Granada. Aspectos de cálculo

    Directory of Open Access Journals (Sweden)

    Justo, E.

    2009-06-01

    Full Text Available San Pedro cliff (Figure 1 is a dihedral 65.5 m high, which has progressed to place itself at 23.8 m from the Alhambra wall-palace that is a heritage of the Humankind. Active normal faults surrounding the cliff have created an extension tectonic regime that loosens the ground and activates the slab falls. One of the faces of the dihedral is a major fault. The cliff’s factor of safety subject to the 1000 years return period earthquake is 0.73. The preservation solution proposed is a posttensioned high elastic limit wire mesh and autochthonous vegetation. With this reinforcement, the factor of safety under that earthquake raises to a value around one. A computer simulation has permitted to analyse the environmental impact.La muralla-palacio de La Alhambra, que es Patrimonio de la Humanidad, se ve amenazada por el avance del Tajo de San Pedro (Figura1, un diedro de 65,5 m de altura, que corta la colina de La Alhambra y que se ha situado a sólo 23,8 m de ella. Existe en la zona un régimen tectónico de extensión que afloja el terreno y activa la caída de lajas. Otra causa importante del deterioro del Tajo es la erosión. El coeficiente de seguridad al deslizamiento del Tajo sometido al terremoto de periodo de retorno de 1.000 años es de 0,73. La solución propuesta para su preservación es una malla de alambre postesada de alto límite elástico y revegetación autóctona. La presión que puede llegar a aplicar la malla en servicio eleva el coeficiente de seguridad con sismo a un valor próximo a uno. Mediante una simulación en ordenador se ha analizado el impacto ambiental.

  12. Conservación y restauración de un tocado atacameño del sitio Solcor-3, San Pedro de Atacama, norte de Chile

    Directory of Open Access Journals (Sweden)

    Carolina Andrea Morales Nilo

    2014-12-01

    Full Text Available En la colección de tocados cefálicos prehispánicos asociados a contextos funerarios del Instituto de Investigaciones Arqueológicas y Museo R.P. Gustavo Le Paige (I.I.A.M., San Pedro de Atacama, existe un tocado atacameño poco usual conformado por una banda afelpada y un casquete cuadrado. El presente artículo expone los procesos de documentación, diagnóstico y tratamiento de conservación aplicado a este tocado atacameño, procedente del fardo funerario de un individuo de la tumba 112 del sitio Solcor 3, asociado a la fase de influencia del estado Tiwanaku en San Pedro de Atacama.

  13. Development of a Shared Vision for Groundwater Management to Protect and Sustain Baseflows of the Upper San Pedro River, Arizona, USA

    Directory of Open Access Journals (Sweden)

    Holly E. Richter

    2014-08-01

    Full Text Available Groundwater pumping along portions of the binational San Pedro River has depleted aquifer storage that supports baseflow in the San Pedro River. A consortium of 23 agencies, business interests, and non-governmental organizations pooled their collective resources to develop the scientific understanding and technical tools required to optimize the management of this complex, interconnected groundwater-surface water system. A paradigm shift occurred as stakeholders first collaboratively developed, and then later applied, several key hydrologic simulation and monitoring tools. Water resources planning and management transitioned from a traditional water budget-based approach to a more strategic and spatially-explicit optimization process. After groundwater modeling results suggested that strategic near-stream recharge could reasonably sustain baseflows at or above 2003 levels until the year 2100, even in the presence of continued groundwater development, a group of collaborators worked for four years to acquire 2250 hectares of land in key locations along 34 kilometers of the river specifically for this purpose. These actions reflect an evolved common vision that considers the multiple water demands of both humans and the riparian ecosystem associated with the San Pedro River.

  14. Development of a shared vision for groundwater management to protect and sustain baseflows of the Upper San Pedro River, Arizona, USA

    Science.gov (United States)

    Richter, Holly E.; Gungle, Bruce; Lacher, Laurel J.; Turner, Dale S.; Bushman, Brooke M.

    2014-01-01

    Groundwater pumping along portions of the binational San Pedro River has depleted aquifer storage that supports baseflow in the San Pedro River. A consortium of 23 agencies, business interests, and non-governmental organizations pooled their collective resources to develop the scientific understanding and technical tools required to optimize the management of this complex, interconnected groundwater-surface water system. A paradigm shift occurred as stakeholders first collaboratively developed, and then later applied, several key hydrologic simulation and monitoring tools. Water resources planning and management transitioned from a traditional water budget-based approach to a more strategic and spatially-explicit optimization process. After groundwater modeling results suggested that strategic near-stream recharge could reasonably sustain baseflows at or above 2003 levels until the year 2100, even in the presence of continued groundwater development, a group of collaborators worked for four years to acquire 2250 hectares of land in key locations along 34 kilometers of the river specifically for this purpose. These actions reflect an evolved common vision that considers the multiple water demands of both humans and the riparian ecosystem associated with the San Pedro River.

  15. Application of Hydrologic Tools and Monitoring to Support Managed Aquifer Recharge Decision Making in the Upper San Pedro River, Arizona, USA

    Directory of Open Access Journals (Sweden)

    Laurel J. Lacher

    2014-11-01

    Full Text Available The San Pedro River originates in Sonora, Mexico, and flows north through Arizona, USA, to its confluence with the Gila River. The 92-km Upper San Pedro River is characterized by interrupted perennial flow, and serves as a vital wildlife corridor through this semiarid to arid region. Over the past century, groundwater pumping in this bi-national basin has depleted baseflows in the river. In 2007, the United States Geological Survey published the most recent groundwater model of the basin. This model served as the basis for predictive simulations, including maps of stream flow capture due to pumping and of stream flow restoration due to managed aquifer recharge. Simulation results show that ramping up near-stream recharge, as needed, to compensate for downward pumping-related stress on the water table, could sustain baseflows in the Upper San Pedro River at or above 2003 levels until the year 2100 with less than 4.7 million cubic meters per year (MCM/yr. Wet-dry mapping of the river over a period of 15 years developed a body of empirical evidence which, when combined with the simulation tools, provided powerful technical support to decision makers struggling to manage aquifer recharge to support baseflows in the river while also accommodating the economic needs of the basin.

  16. Ecosystem services valuation to support decisionmaking on public lands—A case study of the San Pedro River watershed, Arizona

    Science.gov (United States)

    Bagstad, Kenneth J.; Semmens, Darius; Winthrop, Rob; Jaworksi, Delilah; Larson, Joel

    2012-01-01

    This report details the findings of the Bureau of Land Management–U.S. Geological Survey Ecosystem Services Valuation Pilot Study. This project evaluated alternative methods and tools that quantify and value ecosystem services, and it assessed the tools’ readiness for use in the Bureau of Land Management decisionmaking process. We tested these tools on the San Pedro River watershed in northern Sonora, Mexico, and southeast Arizona. The study area includes the San Pedro Riparian National Conservation Area (managed by the Bureau of Land Management), which has been a focal point for conservation activities and scientific research in recent decades. We applied past site-specific primary valuation studies, value transfer, the Wildlife Habitat Benefits Estimation Toolkit, and the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) and Artificial Intelligence for Ecosystem Services (ARIES) models to value locally important ecosystem services for the San Pedro River watershed—water, carbon, biodiversity, and cultural values. We tested these approaches on a series of scenarios to evaluate ecosystem service changes and the ability of the tools to accommodate scenarios. A suite of additional tools were either at too early a stage of development to run, were proprietary, or were place-specific tools inappropriate for application to the San Pedro River watershed. We described the strengths and weaknesses of these additional ecosystem service tools against a series of evaluative criteria related to their usefulness for Bureau of Land Management decisionmaking. Using these tools, we quantified gains or losses of ecosystem services under three categories of scenarios: urban growth, mesquite management, and water augmentation. These results quantify tradeoffs and could be useful for decisionmaking within Bureau of Land Management district or field offices. Results are accompanied by a relatively high level of uncertainty associated with model outputs, valuation

  17. Comparing approaches to spatially explicit ecosystem service modeling: a case study from the San Pedro River, Arizona

    Science.gov (United States)

    Bagstad, Kenneth J.; Semmens, Darius J.; Winthrop, Robert

    2013-01-01

    Although the number of ecosystem service modeling tools has grown in recent years, quantitative comparative studies of these tools have been lacking. In this study, we applied two leading open-source, spatially explicit ecosystem services modeling tools – Artificial Intelligence for Ecosystem Services (ARIES) and Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) – to the San Pedro River watershed in southeast Arizona, USA, and northern Sonora, Mexico. We modeled locally important services that both modeling systems could address – carbon, water, and scenic viewsheds. We then applied managerially relevant scenarios for urban growth and mesquite management to quantify ecosystem service changes. InVEST and ARIES use different modeling approaches and ecosystem services metrics; for carbon, metrics were more similar and results were more easily comparable than for viewsheds or water. However, findings demonstrate similar gains and losses of ecosystem services and conclusions when comparing effects across our scenarios. Results were more closely aligned for landscape-scale urban-growth scenarios and more divergent for a site-scale mesquite-management scenario. Follow-up studies, including testing in different geographic contexts, can improve our understanding of the strengths and weaknesses of these and other ecosystem services modeling tools as they move closer to readiness for supporting day-to-day resource management.

  18. La antigua iglesia de San Pedro (Íscar, Valladolid. Evidencias arquitectónicas románicas

    Directory of Open Access Journals (Sweden)

    Esteban Molina, Jorge

    2015-03-01

    Full Text Available Saint Peter is the great unknown of the Iscar churches due to the demolition of most of its architectural structures and the insufficient characteristics of the scarcely preserved evidence, hidden between contemporary buildings. Nevertheless, the recent demolition of one of the buildings attached to the eastern side of the former temple, where the Romanesque remains are concentrated, has brought to light a decisive part of the apse and the presbytery along with the front closure of the southern aisle. This discovery has allowed an indepth analysis and an approach to what could have been the primitive building.San Pedro es la gran desconocida de las iglesias de Íscar a consecuencia de la demolición de la mayor parte de sus estructuras arquitectónicas y de la insuficiente representatividad de las escasas evidencias conservadas, enmascaradas entre edificios contemporáneos. Sin embargo, el reciente derribo de uno de los inmuebles adosados en el extremo oriental del antiguo templo, donde se concentran los restos del periodo románico, ha sacado a la luz una parte determinante del ábside y el presbiterio así como el testero de cierre de la nave meridional, permitiendo su análisis en profundidad y una aproximación a lo que pudo ser la primitiva construcción.

  19. Abundance and distribution of lantern fishes (Myctophiformes: Myctophidae around San Pedro Martir Island, Gulf of California, during 2008

    Directory of Open Access Journals (Sweden)

    Mariana Díaz Santana-Iturríos

    2013-07-01

    Full Text Available Myctophids (Myctophidae are a group of abundant mesopelagic fishes in the world's oceans and are known as the main feeding resource for several high trophic level predators. Changes in abundance may be related to population size of some commercially important species that feed on them. Only two of the myctophid species reported for the Gulf of California were found in the present study: Benthosema panamense and Triphoturus mexicanus. The highest abundance and biomass of myctophids were found during the warm season (June and September, with B. panamense being the most abundant species (20,954 ind 1000 m-3, as well as the one with highest biomass (17,165.8 g 1000 m-3. B. panamese had a size mode interval of 35-40 mm, while T. mexicanus presented a size mode interval of 40-45 mm; both species had negative allometric growth. During the temperate season (February and April B. panamense was distributed in the northwest, west, and southern regions around the island, while T. mexicanus was found in the north, west, and southern regions. During the warm season B. panamense was found distributed around the entire island and T. mexicanus was found in the west, south, and east regions of the island. These species are common around San Pedro Martir Island, with the highest values of abundance and biomass occurring during summer upwelling's.

  20. Assessing hydrologic impacts of future Land Change scenarios in the San Pedro River (U.S./Mexico)

    Science.gov (United States)

    Kepner, W. G.; Burns, S.; Sidman, G.; Levick, L.; Goodrich, D. C.; Guertin, P.; Yee, W.; Scianni, M.

    2012-12-01

    An approach was developed to characterize the hydrologic impacts of urban expansion through time for the San Pedro River, a watershed of immense international importance that straddles the U.S./Mexico border. Future urban growth is a key driving force altering local and regional hydrology and is represented by decadal changes in housing density maps from 2010 to 2100 derived from the Integrated Climate and Land-Use Scenarios (ICLUS) database. ICLUS developed future housing density maps by adapting the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES) social, economic, and demographic storylines to the conterminous United States. To characterize the hydrologic impacts of future growth, the housing density maps were reclassified to National Land Cover Database 2006 land cover classes and used to parameterize the Soil and Water Assessment Tool (SWAT) using the Automated Geospatial Watershed Assessment (AGWA) tool. The presentation will report 1) the methodology for adapting the ICLUS data for use in AGWA as an approach to evaluate basin-wide impacts of development on water-quantity and -quality, 2) initial results of the application of the methodology, and 3) discuss implications of the analysis.

  1. Perfiles anhelados. Correspondencia de lenguajes y estéticas entre el Cementerio San Pedro y la red social Facebook

    Directory of Open Access Journals (Sweden)

    Eloisa Lamilla Guerrero

    2016-09-01

    Full Text Available This article aims to analyze, through ethnographic observation of the Cemetery San Pedro in Medellin (Colombia, the recent trend of tombstones decoration in confluence with the proposal of structure and aesthetics of the social network Facebook. This correlation between the virtual language of Facebook and the ritual language of the tombs, is much more complex than a mere coincidence so we propose a thorough comparative reading of these two universes of representation for the meeting and communication, is needed to provide a better understanding of the two phenomena. Both are plethoric spaces that reveal the relentless pursuit of the subject to perpetuate their presence, to tell about their lives and deaths, to eternalize their expressions of affection, love and devotion, and to continue their social relationships despite physical or virtual distance, as scenarios with common origins and intentions, where appearing is more important than being. Currently, the “walls” of both the Cemetery and Facebook, serve as communicational sceneries that share publicly and shamelessly intimate details; where family relationships are announced; idyllic havens are displayed as photographic backgrounds; messages are left and profiles with the strong necessity to achieve the long-awaited update transcendence.

  2. Diversity and biogeography of bacterial assemblages in surface sediments across the San Pedro Basin, Southern California Borderlands.

    Science.gov (United States)

    Hewson, Ian; Jacobson Meyers, Myrna E; Fuhrman, Jed A

    2007-04-01

    Sediment bacteria play important roles in the biogeochemistry of ocean sediments; however, factors influencing assemblage composition have not been extensively studied. We examined extractable sediment bacterial abundance, the composition of bacterial assemblages using a high-throughput molecular fingerprinting approach, and several sediment biogeochemical parameters (organic matter content and alkaline phosphatase activity), along a 35 km transect from Point Fermin, Southern California, to Santa Catalina Island, across the approximately 900-m-deep San Pedro Basin. Automated rRNA intergenic spacer analysis (ARISA) demonstrated that in two spatially isolated shallow (approximately sediment environments, assemblages were more similar to each other than to deeper communities. Distinct communities existed in deeper and shallower sediments, and stations within the deep basin over 2 km apart contained remarkably similar assemblage fingerprints. The relative contribution to total amplified DNA fluorescence of operational taxonomic units (OTUs) was significantly correlated to that of other OTUs in few comparisons (2.7% of total), i.e. few bacterial types were found together or apart consistently. The relative proportions within assemblages of only a few OTU were significantly correlated to measured physicochemical parameters (organic matter content and wet/dry weight ratio of sediments) or enzyme (alkaline phosphatase) activities. A low percentage of shared OTU between shallow and deep sediments, and the presence of similar, but spatially isolated assemblages suggests that bacterial OTU may be widely dispersed over scales of a few kilometres, but that environmental conditions select for particular assemblages.

  3. Vegetation history along the eastern, desert escarpment of the Sierra San Pedro Mártir, Baja California, Mexico

    Science.gov (United States)

    Holmgren, Camille A.; Betancourt, Julio L.; Rylander, Kate A.

    2011-05-01

    Plant macrofossils from 38 packrat middens spanning the last ~ 33,000 cal yr BP record vegetation between ~ 650 and 900 m elevation along the eastern escarpment of the Sierra San Pedro Mártir, northern Baja California. The middens span most of the Holocene, with a gap between ~ 4600 and 1800 cal yr BP, but coverage in the Pleistocene is uneven with a larger hiatus between 23,100 and 14,400 cal yr BP. The midden flora is relatively stable from the Pleistocene to Holocene. Exceptions include Pinus californiarum, Juniperus californica and other chaparral elements that were most abundant > 23,100 cal yr BP and declined after 14,400 cal yr BP. Despite being near the chaparral/woodland-desertscrub ecotone during glacial times, the midden assemblages reflect none of the climatic reversals evident in the glacial or marine record, and this is corroborated by a nearby semi-continuous pollen stratigraphy from lake sediments. Regular appearance of C 4 grasses and summer-flowering annuals since 13,600 cal yr BP indicates occurrence of summer rainfall equivalent to modern (JAS average of ~ 80-90 mm). This casts doubt on the claim, based on temperature proxies from marine sediments in the Guaymas Basin, that monsoonal development in the northern Gulf and Arizona was delayed until after 6200 cal yr BP.

  4. Vegetation history along the eastern, desert escarpment of the Sierra San Pedro Mártir, Baja California, Mexico

    Science.gov (United States)

    Holmgren, Camille A.; Betancourt, Julio L.; Rylander, Kate A.

    2011-01-01

    Plant macrofossils from 38 packrat middens spanning the last ~ 33,000 cal yr BP record vegetation between ~ 650 and 900 m elevation along the eastern escarpment of the Sierra San Pedro Mártir, northern Baja California. The middens span most of the Holocene, with a gap between ~ 4600 and 1800 cal yr BP, but coverage in the Pleistocene is uneven with a larger hiatus between 23,100 and 14,400 cal yr BP. The midden flora is relatively stable from the Pleistocene to Holocene. Exceptions include Pinus californiarum, Juniperus californica and other chaparral elements that were most abundant > 23,100 cal yr BP and declined after 14,400 cal yr BP. Despite being near the chaparral/woodland-desertscrub ecotone during glacial times, the midden assemblages reflect none of the climatic reversals evident in the glacial or marine record, and this is corroborated by a nearby semi-continuous pollen stratigraphy from lake sediments. Regular appearance of C4 grasses and summer-flowering annuals since 13,600 cal yr BP indicates occurrence of summer rainfall equivalent to modern (JAS average of ~ 80–90 mm). This casts doubt on the claim, based on temperature proxies from marine sediments in the Guaymas Basin, that monsoonal development in the northern Gulf and Arizona was delayed until after 6200 cal yr BP.

  5. Geoprocesamiento aplicado al analisis del uso de la tierra en el municipio de San Pedro de Ycuamandyyú, Paraguay.

    Directory of Open Access Journals (Sweden)

    Oscar Agustín Torres Figueredo

    2010-08-01

    Full Text Available El municipio de San Pedro de Ycuamandyyú está ubicado en el noroeste de la región oriental del Paraguay. Los objetivos de este trabajo constituyen la elaboración y el análisis del mapa del uso de la tierra para la planificación de actividades forestales en la zona, para los cuales se utilizaron técnicas de cartografía, sensores remotos y (SIG Sistemas de Informaciones Geográficas, que posibilitaron el análisis de informaciones provenientes de imágenes satelitales LANDSAT TM 5, de cartas topográficas y de (GPS Sistema de Posicionamiento Global, que permitió el procesamiento de datos en el programa Idrisi 2.0 para la confección de un mapa que posibilitó el análisis sobre la situación del uso de la tierra en el municipio. Se distinguió categorías predominantes como praderas altas o campos naturales, uso agropecuario y praderas bajas o bañados, siendo la cobertura forestal con valor inferior al 25%. Se concluyó que el municipio presenta bastantes áreas de campos naturales y uso agropecuario que podrían utilizarse para actividades de reforestación, sea con especies nativas o exóticas de rápido crecimiento con la finalidad de obtener valores de cobertura forestal en equilibrio con las demás categorías de uso de la tierra.

  6. GEOPROCESAMIENTO APLICADO AL ANALISIS DEL USO DE LA TIERRA EN EL MUNICIPIO DE SAN PEDRO DE YCUAMANDYYÚ, PARAGUAY

    Directory of Open Access Journals (Sweden)

    Oscar Agustín Torres Figueredo

    2002-10-01

    Full Text Available El municipio de San Pedro de Ycuamandyyú está ubicado en el noroeste de la región oriental del Paraguay. Los objetivos de este trabajo constituyen la elaboración y el análisis del mapa del uso de la tierra para la planificación de actividades forestales en la zona, para los cuales se utilizaron técnicas de cartografía, sensores remotos y (SIG Sistemas de Informaciones Geográficas, que posibilitaron el análisis de informaciones provenientes de imágenes satelitales LANDSAT TM 5, de cartas topográficas y de (GPS Sistema de Posicionamiento Global, que permitió el procesamiento de datos en el programa Idrisi 2.0 para la confección de un mapa que posibilitó el análisis sobre la situación del uso de la tierra en el municipio. Se distinguió categorías predominantes como praderas altas o campos naturales, uso agropecuario y praderas bajas o bañados, siendo la cobertura forestal con valor inferior al 25%. Se concluyó que el municipio presenta bastantes áreas de campos naturales y uso agropecuario que podrían utilizarse para actividades de reforestación, sea con especies nativas o exóticas de rápido crecimiento con la finalidad de obtener valores de cobertura forestal en equilibrio con las demás categorías de uso de la tierra.

  7. Geoprocesamiento aplicado al analisis del uso de la tierra en el municipio de San Pedro de Ycuamandyyú , Paraguay

    Directory of Open Access Journals (Sweden)

    Oscar Agustín Figueredo Torres

    2002-01-01

    Full Text Available El municipio de San Pedro de Ycuamandyyú está ubicado en el noroeste de la región oriental del Paraguay. Los objetivos de este trabajo constituyen la elaboración y el análisis del mapa del uso de la tierra para la planificación de actividades forestales en la zona, para los cuales se utilizaron técnicas de cartografía, sensores remotos y (SIG Sistemas de Informaciones Geográficas, que posibilitaron el análisis de informaciones provenientes de imágenes satelitales LANDSAT TM 5, de cartas topográficas y de (GPS Sistema de Posicionamiento Global, que permitió el procesamiento de datos en el programa Idrisi 2.0 para la confección de un mapa que posibilitó el análisis sobre la situación del uso de la tierra en el municipio. Se distinguió categorías predominantes como praderas altas o campos naturales, uso agropecuario y praderas bajas o bañados, siendo la cobertura forestal con valor inferior al 25%. Se concluyó que el municipio presenta bastantes áreas de campos naturales y uso agropecuario que podrían utilizarse para actividades de reforestación, sea con especies nativas o exóticas de rápido crecimiento con la finalidad de obtener valores de cobertura forestal en equilibrio con las demás categorías de uso de la tierra.

  8. LA EVALUACIÓN DEL IMPACTO AMBIENTAL Y EL DESARROLLO SUSTENTABLE. ESTUDIO DE CASO SAN PEDRO MIXTEPEC, JUQUILA, OAXACA.

    Directory of Open Access Journals (Sweden)

    Carlos Espinoza-Nájera

    2012-01-01

    Full Text Available La problemática en materia de impacto ambiental en México está referida a que no se ha realizado una evaluación sobre su efectividad como instrumento de la política ambiental, por lo que es importante conocer si dicho instrumento cumple o coadyuva con los principios básicos del desarrollo sustentable, considerando que debe evolucionar y estar en un proceso de mejora continua. Debe garantizarse, efectivamente, el enfoque preventivo que brinde certeza acerca de la factibilidad ambiental de los diversos proyectos con los cuales se busca promover el desarrollo. En este trabajo se aplicó un sistema de investigación hipotético-deductivo, a través del método empírico descriptivo y correlacional, realizando la recopilación, análisis y evaluación de información existente, principalmente de las manifestaciones de impacto ambiental de proyectos de desarrollo con dictamen técnico, en San Pedro Mixtepec, Juquila, Oaxaca. El resultado demuestra que la información es superficial, y no aporta conocimiento científico sobre los verdaderos impactos que generará el proyecto o actividad al medio ambiente y a los recursos naturales. Se puede concluir que dichos documentos desempeñan un papel preponderante, ya que permiten identificar los impactos ambientales negativos y, al mismo tiempo, armonizar estos efectos aplicando medidas de prevención o mitigación que favorezcan el equilibrio entre el desarrollo y la conservación del ambiente.

  9. Recent deformation on the San Diego Trough and San Pedro Basin fault systems, offshore Southern California: Assessing evidence for fault system connectivity.

    Science.gov (United States)

    Bormann, J. M.; Kent, G. M.; Driscoll, N. W.; Harding, A. J.

    2016-12-01

    The seismic hazard posed by offshore faults for coastal communities in Southern California is poorly understood and may be considerable, especially when these communities are located near long faults that have the ability to produce large earthquakes. The San Diego Trough fault (SDTF) and San Pedro Basin fault (SPBF) systems are active northwest striking, right-lateral faults in the Inner California Borderland that extend offshore between San Diego and Los Angeles. Recent work shows that the SDTF slip rate accounts for 25% of the 6-8 mm/yr of deformation accommodated by the offshore fault network, and seismic reflection data suggest that these two fault zones may be one continuous structure. Here, we use recently acquired CHIRP, high-resolution multichannel seismic (MCS) reflection, and multibeam bathymetric data in combination with USGS and industry MCS profiles to characterize recent deformation on the SDTF and SPBF zones and to evaluate the potential for an end-to-end rupture that spans both fault systems. The SDTF offsets young sediments at the seafloor for 130 km between the US/Mexico border and Avalon Knoll. The northern SPBF has robust geomorphic expression and offsets the seafloor in the Santa Monica Basin. The southern SPBF lies within a 25-km gap between high-resolution MCS surveys. Although there does appear to be a through-going fault at depth in industry MCS profiles, the low vertical resolution of these data inhibits our ability to confirm recent slip on the southern SPBF. Empirical scaling relationships indicate that a 200-km-long rupture of the SDTF and its southern extension, the Bahia Soledad fault, could produce a M7.7 earthquake. If the SDTF and the SPBF are linked, the length of the combined fault increases to >270 km. This may allow ruptures initiating on the SDTF to propagate within 25 km of the Los Angeles Basin. At present, the paleoseismic histories of the faults are unknown. We present new observations from CHIRP and coring surveys at

  10. Diagnóstico Estructural y Análisis Sísmico de la Iglesia San Pedro Apóstol de Andahuaylillas

    OpenAIRE

    Briceño Melendez, Carolina Paola

    2016-01-01

    Las construcciones históricas representan parte de la identidad de los pueblos y son fuente importante de ingresos por el turismo, por lo que son de gran relevancia para el desarrollo de un país. En el Perú, existe un gran número de edificios patrimoniales de adobe siendo la iglesia San Pedro Apóstol de Andahuaylillas, una de las construcciones más representativas de los Andes peruanos. Este templo, el cual está ubicado en la Plaza de Armas del pueblo de Andahuaylillas en Cusco...

  11. FACTORES DE RIESGO BIOPSICOSOCIAL QUE INFLUYEN EN EL FRACASO ESCOLAR EN ALUMNOS VULNERABLES DE ESCUELAS MUNICIPALIZADAS DE LA COMUNA DE SAN PEDRO DE LA PAZ, 2005

    OpenAIRE

    VALDERRAMA ALARCON,MILADY; BEHN THEUNE,VERÓNICA; PEREZ VILLALOBOS,MARIA VICTORIA; DIAZ MUJICA,ALEJANDRO; CID HENRIQUEZ,PATRICIA; TORRUELLA PUENTE,MATILDE

    2007-01-01

    Estudio descriptivo correlacional de corte transversal, cuyo propósito fue conocer las características de salud en las dimensiones biológicas y psicosociales de escolares de alta vulnerabilidad y relacionarlas con su rendimiento y fracaso escolar. El grupo de estudio estuvo constituido por 148 escolares de segundo año básico, de dos escuelas de San Pedro de la Paz, Concepción, Chile, cuyos índices de vulnerabilidad escolar correspondían a 62% y 46,3% respectivamente, según encuesta de la Junt...

  12. Spatial Digital Database for the Geology of the San Pedro River Basin in Cochise, Gila, Graham, Pima, and Pinal Counties, Arizona

    Science.gov (United States)

    Bolm, Karen S.

    2002-01-01

    This spatial digital database for the geology of the San Pedro River Basin in southeastern Arizona was compiled from three maps by Dickinson (1993, 1998, 2000). Mylar originals of the map sheets were scanned, and the resultant images were rectified to a mathematically-generated set of latitude and longitude registration points. Geologic linework was digitized from the rectified images on screen using ArcView (ver. 3.2), and the resultant shapefiles were converted to ArcInfo (ver. 7.2) coverages. Lines and polygons were then attributed; and the files were merged omtp a single ArcInfo database (quib24k).

  13. CALIDAD DE VIDA Y DIMORFISMO SEXUAL EN LA POBLACIÓN PREHISPÁNICA DE SAN PEDRO DE ATACAMA (NORTE DE CHILE)

    OpenAIRE

    Cocilovo,José; Varela,Héctor; Fuchs,María

    2014-01-01

    La diferencia morfológica entre sexos puede variar reflejando la calidad de vida dominante en una población. La información para San Pedro de Atacama es analizada para evaluar a partir de una muestra de 624 individuos y 35 variables craneométricas. Las diferencias entre sexos se analizaron con las pruebas ANCOVA y MANCOVA para una y dos vías con covariantes, según el caso. El análisis discriminante (DA) permitió evaluar la clasificación del sexo en cada individuo. La mayoría de las mediciones...

  14. Dendrocronología de Alnus acuminata en el bosque reservado de San Pedro de Saño, Huancayo

    Directory of Open Access Journals (Sweden)

    Edilson Requena Rojas

    2015-12-01

    Full Text Available En este trabajo evaluamos el potencial de Alnus acuminata para su uso posterior en estudios dendroclimatológicos. Se analizó una cronología de ancho de anillos para un bosque de A. acuminata en San Pedro de Saño y se relacionó el crecimiento de los árboles con los registros instrumentales de temperatura media, máxima y mínima, precipitación y horas sol de las estaciones meteorológicas de Huayao (12° 02´ 18.1¨ S - 75° 19´22.2¨ O y Santa Ana (12° 00´ 15¨ S - 75° 13´ 15¨ O. La cronología de ancho de anillos está compuesta por 33 series de 22 árboles y cubre el período 1968-2013. El crecimiento de los árboles estuvo relacionado negativamente con la temperatura mínima mensual del mes de abril del año corriente. Se observó una relación positiva y significativa entre la cronología de crecimiento y la precipitación de la estación de Santa Ana para los meses de marzo del año previo y diciembre del año actual de crecimiento. Las horas sol mensuales de abril del año corriente tienen una correlación significativa con el crecimiento radial. Existe influencia de las precipitaciones del verano previo y primavera del año corriente favoreciendo el crecimiento del árbol. El árbol entra en dormancia, posiblemente por las bajas temperaturas de otoño. El amplio rango de distribución y la utilización histórica de su madera en construcciones en el pasado, abre la posibilidad de extender temporalmente los registros dendrocronológicos, en los Andes centrales de Perú.

  15. Factores de riesgo relacionados al uso de drogas ilegales: perspectiva crítica de familiares y personas cercanas en un centro de salud público en San Pedro Sula, Honduras Fatores de risco relacionados ao uso de drogas ilegais, perspectiva crítica de familiares e pessoas próximas, em um centro da saúde público em San Pedro Sula, Honduras Risk factors related to the use of illegal drugs: the critial perspective of drug users' relatives and acquaintances at a public health center in San Pedro Sula, Honduras

    National Research Council Canada - National Science Library

    Gladys Magdalena Rodríguez Funes; Bruna Brands; Edward Adlaf; Norman Giesbrecht; Laura Simich; Maria da Gloria Miotto Wright

    2009-01-01

    ... público en San Pedro Sula, en Honduras. Su objetivo es describir la perspectiva crítica que tienen los familiares o personas, que se consideran afectadas por tener a alguien cercano que usa o ha usado drogas ilegales, con...

  16. San Pedro Hacienda Hotel

    Directory of Open Access Journals (Sweden)

    Neutra, Richard J.

    1960-05-01

    Full Text Available Una de las arterias principales de Los Angeles, la carretera de acceso desde Western Avenue, que relaciona la ciudad con su puerto, permite llegar fácilmente, a través de una pequeña desviación, a la entrada principal del hotel. El sencillo grupo de edificios que lo constituyen, se amolda a la pendiente del terreno, acusando el juego de volúmenes y de sol y sombra para aumentar el interés visual. Al fondo, la severidad del paisaje montañoso contrasta con la tranquilidad del mar, que en este caso, pese a ser el Océano Pacífico el gran mar occidental americano, aparece al E., por estar el edificio situado en la orilla oriental de la península de Falos Verdes.

  17. Using Lidar to distinguish leaf area index in cottonwood trees and improve riparian water use estimates in the Upper San Pedro River Basin

    Science.gov (United States)

    Farid, A.; Goodrich, D.; Durcik, M.; Sorooshian, S.

    2007-12-01

    Estimation of riparian forest structural attributes, such as the Leaf Area Index (LAI), is an important step in identifying the amount of water use in riparian forest areas. In this research, small footprint lidar data were used to estimate biophysical properties of young, mature, and old cottonwood trees in the Upper San Pedro River Basin, Arizona, USA. Canopy height and maximum and mean laser heights were derived for the cottonwood trees from lidar data. Linear regression models were used to develop equations relating lidar height metrics with corresponding field measured LAI for each age class of cottonwoods. Four metrics (tree height, height of median energy, ground return ratio, and canopy return ratio) were derived by synthetically constructing a large footprint lidar waveform from small-footprint lidar data which were compared to ground-based high- resolution Intelligent Laser Ranging and Imaging System (ILRIS) scanner images. These four metrics were incorporated into a stepwise regression procedure to predict field-derived LAI for different age classes of cottonwoods. The Penman-Monteith model was then used to estimate transpiration of the cottonwoods using the lidar-derived canopy metrics. These transpiration estimates compared very well to ground-based sap flux transpiration estimates indicating lidar-derived LAI can be used to improve riparian cottonwood water-use estimates. Future research will attempt to fuse high spatial resolution multispectral or hyperspectral data and lidar data to improve classification results for species identification in the Upper San Pedro River Basin.

  18. Documentación del fondo de Oseira (AHN relacionada con el monasterio San Pedro de Vilanova de Dozón (1015-1295

    Directory of Open Access Journals (Sweden)

    Romaní Martínez, Miguel

    2003-12-01

    Full Text Available After the introduction and the criteria for transcription, we publish 25 documents of the 11>sub>th 12th and 13thcenturies belonging to the collection of Oseira at the AHN related to the monastery of San Pedro de Vilanova de Dozon, in Tierra de Deza (Pontevedra. The suggested periods make it possible to observe the transition from the Visigothic writing to the Carolingian. We also include an appendix with tables of diplomatic and paléographie analyses, a sample of the most representative writings, onomastic and toponymie indices, and a bibliography.

    Tras la introducción y criterios de transcripción, se editan 25 documentos de los siglos XI, XII y XIII pertenecientes al fondo de Oseira del AHN relacionados con el monasterio de San Pedro de Vilanova de Dozón, en Tierra de Deza (Pontevedra. Las fechas propuestas permiten observar el paso de la escritura visigótica a la Carolina. Se incluye un apéndice con tablas de análisis diplomático y paleográfico, una muestra de las escrituras más representativas, índices onomástico y toponímico, y bibliografía.

  19. Flebotominos (Diptera: Psychodidae de San Pedro, distrito Kosñipata, Paucartambo - Cusco, y nuevos reportes para el Perú

    Directory of Open Access Journals (Sweden)

    Abraham Cáceres L

    2001-01-01

    Full Text Available Objetivo: Entre el 13 y 17 de setiembre de 1999, se realizaron colectas de flebotominos en la localidad de San Pedro, distrito Kosñipata, provincia Paucartambo, departamento Cusco, para conocer la diversidad de las especies presentes. Materiales y Métodos: Las colectas fueron con: a trampa de luz (CDC colocadas en peri y extradomiciliarios, y b mediante cebo humano realizados en intra y peridomiciliarios. Resultados: Se obtuvieron cinco especies de flebotominos pertenecientes a Lutzomyia (Helcocyrtomyia guderiani (71%, Pintomyia (Pifanomyia tocaniensis (23%, Pintomyia (Pifanomyia saupiensis (3%, Psathyromyia (Forattiniella abuanensis (2% y Psathyromyia (Forattiniella aragaoi (1%, de las cuales tres especies son reportes nuevos para el Perú. Conclusiones: Se amplía la distribución geográfica de Lu. guderiani, P. tocaniensis y P. saupiensis desde los 16°06’ LS y 67°44’ LW (Suapi, Yungas, La Paz-Bolivia hasta los 13°03'19" LS y 71°32'48" LW (San Pedro, Kosñipata, Cusco-Perú. Además, se menciona que tres de las cinco especies encontradas podrían ocasionar casos de leishmaniasis tegumentaria y/o enfermedad de Carrión (verruga peruana.

  20. Desarrollo de un programma de rehabilitación cardiaca en la clínica San Pedro Claver, mediante un sistema efectivo de integración y comunicación

    Directory of Open Access Journals (Sweden)

    Blanca Cruz de Linares

    1990-04-01

    Full Text Available RESUMEN La  rehablitación cardica debe convertirse en una actividad prioritaria en la Clínica San Pedro Claver, aprovechando los recursos existentes, recursos físicos y algunos recursos tecnológicos.

  1. Cómo se construye una torre mudéjar. La torre de la iglesia de San Pedro el Viejo de Madrid

    Directory of Open Access Journals (Sweden)

    Caballero Zoreda, Luis

    2004-12-01

    Full Text Available The Mudejar tower of San Pedro el Viejo de Madrid offers, thanks to various modern-era and contemporary interventions, the possibility of analyzing its unknown construction process and construction tecniques combining brick and limestone stonework. A wall of brick and mud was used as the formwork of limestone walls and then used as a base for the first sections and staircase. The wood and brick walls on view were also used as formwork.La torre mudéjar de S. Pedro el Viejo de Madrid ofrece, gracias a diversas intervenciones de época moderna y contemporánea, la posibilidad de analizar su desconocido proceso de construcción y sus técnicas constructivas donde se combinan fábricas de ladrillo y calicanto. Un muro de ladrillo con barro sirvió de encofrado de la fábrica de calicanto y luego fue utilizado como base de los primeros tramos de la escalera. También se utilizaron como encofrado la madera y los muros de ladrillo visto.

  2. Pedro de Castañeda: su pintura para el refectorio del Colegio Mayor de San Ildefonso (1553

    Directory of Open Access Journals (Sweden)

    González Ramos, Roberto

    2003-09-01

    Full Text Available El pintor Pedro de Castañeda es un artista poco conocido, activo en la zona de Alcalá de Henares en las décadas centrales del siglo XVI. Se sabe que junto a su hijo Juan fue colaborador del entallador y traductor de Vitruvio Miguel de Urrea. Pedro de Castañeda pintó un cirial que había tallado Urrea para la iglesia parroquial de Camarma de Esteruelas, trabajo por el que ambos cobraron cierta cantidad en 1540, y en 1550 colaboró con ese entallador y con Claudio de Arciniega, ayudado por Juan, en la obra de los retablos colaterales de la iglesia de Daganzo de Arriba (perdidos, realizando su pintura. Parece que se trata del mismo artista el Pedro Castañeda que se documenta trabajando en la zona de Segovia, concretamente en dos retablos para la iglesia de Cascajares del Fresno. Falleció en 1557…

  3. El turismo de naturaleza en espacios naturales. El caso del Parque Regional de las Salinas y Arenales de San Pedro del Pinatar

    Directory of Open Access Journals (Sweden)

    Gustavo A. Ballesteros Pelegrín

    2014-01-01

    Full Text Available Los espacios naturales atraen a turistas que buscan el contacto con la naturaleza, surgiendo nuevos productos turísticos. Surgen, de este modo, nuevos productos turísticos. En la oferta de turismo de naturaleza del Parque Regional de las Salinas y Arenales de San Pedro del Pinatar destaca: deportes en la naturaleza, aventura y ecoturismo. Este último se divide en: turismo ornitológico y fotográfico, que junto al tradicional de sol y playa y de salud, se ve favorecido por su situación geográfica, condiciones naturales y amplia oferta hotelera. Sin embargo, el turismo cultural basado en la tradición salinera y pesquera no ha sido desarrollado.

  4. CARACTERIZACIÓN QUÍMICA Y MINERALÓGICA DE LAS CROMITAS DE LA ZONA DE BELLO Y SAN PEDRO (DEPARTAMENTO DE ANTIOQUIA

    Directory of Open Access Journals (Sweden)

    Camilo Andres Quintero G.

    2010-10-01

    Full Text Available Se caracterizaron químicamente cinco muestras de cromita de los municipios de Bello y San Pedro (Antioquia en forma semicuantitativa (Análisis Espectrográfico y cuantitativa (Absorción Atómica y Espectroscopia de Emisión con fuente de plasma de Acoplamiento Inductivo; la caracterización mineralógica de las muestras se realizó mediante DRX, ATG y ATD, Microscopía Óptica y Microscopía Electrónica de Barrido con análisis por microsonda SEM-EDS, Estos resultados muestran la factibilidad de utilizar las cromitas de estos sectores como materia prima refractaria por poseer características químicas similares a las cromitas de Cuba o Filipinas que se explotan en la actualidad.

  5. Presence of multi-drug resistant pathogenic Escherichia coli in the San Pedro River located in the State of Aguascalientes, Mexico.

    Science.gov (United States)

    Ramírez Castillo, Flor Y; Avelar González, Francisco J; Garneau, Philippe; Márquez Díaz, Francisco; Guerrero Barrera, Alma L; Harel, Josée

    2013-01-01

    Contamination of surface waters in developing countries is a great concern. Treated and untreated wastewaters have been discharged into rivers and streams, leading to possible waterborne infection outbreaks and may represent a significant dissemination mechanism of antibiotic resistance genes. In this study, the water quality of San Pedro River, the main river and pluvial collector of the Aguascalientes State, Mexico was assessed. Thirty sample locations were tested throughout the River. The main physicochemical parameters of water were evaluated. Results showed high levels of fecal pollution as well as inorganic and organic matter abundant enough to support the heterotrophic growth of microorganisms. These results indicate poor water quality in samples from different locations. One hundred and fifty Escherichia coli were collected and screened by PCR for several virulence genes. Isolates were classified as either pathogenic (n = 91) or commensal (n = 59). The disc diffusion method was used to determine antimicrobial susceptibility to 13 antibiotics. Fifty-two percent of the isolates were resistant to at least one antimicrobial agent and 30.6% were multi-resistant. Eighteen E. coli strains were quinolone resistant of which 16 were multi-resistant. Plasmid-mediated quinolone resistance (PMQR) genes were detected in 12 isolates. Mutations at the Ser-83→Leu and/or Asp-87→Asn in the gyrA gene were detected as well as mutations at the Ser-80→Ile in parC. An E. coli microarray (Maxivirulence V 3.1) was used to characterize the virulence and antimicrobial resistance genes profiles of the fluoroquinolone-resistant isolates. Antimicrobial resistance genes such as bla TEM, sulI, sulII, dhfrIX, aph3 (strA), and tet (B) as well as integrons were found in fluoroquinolone (FQ) resistance E. coli strains. The presence of potential pathogenic E. coli and antibiotic resistance in San Pedro River such as FQ resistant E. coli could pose a potential threat to human and animal

  6. A preliminary evaluation of the San Pedro daisy (Lasianthaea podocephala tuber powder, as a feed additive on the intensive culture of shrimp (Litopenaeus vannamei under laboratory conditions

    Directory of Open Access Journals (Sweden)

    Marcel Martínez-Porchas

    2013-07-01

    Full Text Available An experimental study was carried out during seven weeks to preliminarily evaluate the effect of the dietary inclusion of powder from the tuber Lasianthaeapodocephala, commonly known as the San Pedro daisy or pionilla, as a feed additive on the production parameters, food consumption, and nutritional condition of the white shrimp, Litopenaeus vannamei, intensively farmed under laboratory conditions. Hypothetically, the additive should improve these parameters as it does when used for humans. The powder was included at different levels (0 [Control], 0.2 [T1] and 1 g kg-1 [T2] in a commercial shrimp feed. The tuber powder exhibited a free amino acid profile being arginine (8.59 mg g-1 and glutamine (3.36 mg g-1 the most abundant. Feed consumption was not influenced by any treatment; however, the survival and the overall production responses were higher in both treatments using the powder (T1 and T2 compared to the control. No significant differences were detected in muscle concentrations of lactate and glucose, although higher protein and lower cholesterol concentrations were observed in shrimp reared in the control. The lower cholesterol concentration of shrimp from the control could be associated to a poor nutritional status. In conclusion, addition of the powder of San Pedro daisy did not improve the feed consumption, but apparently had a positive effect on survival, production response and nutritional status of shrimp. These responses could be associated to an hypothetic effect of some plant components at a nutritional-molecular level, or to a possible antimicrobial effect; however, further specific studies are needed.

  7. Cooperación y conflicto entre empresas, comunidades, nuevos movimientos sociales y el papel del gobierno. El caso de cerro de San Pedro (México

    Directory of Open Access Journals (Sweden)

    José G. Vargas-Hernández

    2009-07-01

    Full Text Available El objetivo de este trabajo es analizar las relaciones de cooperación y conflicto entre la Compañía Minera (MSX y las comunidades de San Pedro, Soledad y San Luis Potosí, los Nuevos Movimientos Sociales y los tres niveles de gobierno involucrados. La compañía Minera inició operaciones en una mina a cielo abierto de oro y plata con el apoyo de oficiales de los gobiernos locales, estatales y federal. Los habitantes de estas comunidades apoyados por grupos ambientalistas y Organizaciones No Gubernamentales argumentan que el proyecto contamina las fuentes de agua fresca, además de perturbar el medio ambiente y la ecología de la región. En tal sentido el artículo analiza el impacto, la interacción social y de conflicto entre los distintos actores desde una perspectiva local y socio-ambiental, previa contextualización histórica de subregión y el desarrollo de la industria minera.

  8. Cooperación y conflicto entre empresas, comunidades, nuevos movimientos sociales y el papel del gobierno. El caso de Cerro de San Pedro

    Directory of Open Access Journals (Sweden)

    José G. Vargas-Hernández

    2009-01-01

    Full Text Available El objetivo de este trabajo es analizar las relaciones de cooperación y conflicto entre la Compañía Minera (MSX y las comunidades de San Pedro, Soledad y San Luis Potosí, los Nuevos Movimientos Sociales y los tres niveles de gobierno involucrados. La compañía Minera inició operaciones en una mina a cielo abierto de oro y plata con el apoyo de oficiales de los gobiernos locales, estatales y federal. Los habitantes de estas comunidades apoyados por grupos ambientalistas y Organizaciones No Gubernamentales argumentan que el proyecto contamina las fuentes de agua fresca, además de perturbar el medio ambiente y la ecología de la región. En tal sentido el artículo analiza el impacto, la interacción social y de conflicto entre los distintos actores desde una perspectiva local y socio-ambiental, previa contextualización histórica de subregión y el desarrollo de la industria minera.

  9. Presence of multi-drug resistant pathogenic Escherichia coli in the San Pedro River located in the State of Aguascalientes, Mexico

    Science.gov (United States)

    Ramírez Castillo, Flor Y.; Avelar González, Francisco J.; Garneau, Philippe; Márquez Díaz, Francisco; Guerrero Barrera, Alma L.; Harel, Josée

    2013-01-01

    Contamination of surface waters in developing countries is a great concern. Treated and untreated wastewaters have been discharged into rivers and streams, leading to possible waterborne infection outbreaks and may represent a significant dissemination mechanism of antibiotic resistance genes. In this study, the water quality of San Pedro River, the main river and pluvial collector of the Aguascalientes State, Mexico was assessed. Thirty sample locations were tested throughout the River. The main physicochemical parameters of water were evaluated. Results showed high levels of fecal pollution as well as inorganic and organic matter abundant enough to support the heterotrophic growth of microorganisms. These results indicate poor water quality in samples from different locations. One hundred and fifty Escherichia coli were collected and screened by PCR for several virulence genes. Isolates were classified as either pathogenic (n = 91) or commensal (n = 59). The disc diffusion method was used to determine antimicrobial susceptibility to 13 antibiotics. Fifty-two percent of the isolates were resistant to at least one antimicrobial agent and 30.6% were multi-resistant. Eighteen E. coli strains were quinolone resistant of which 16 were multi-resistant. Plasmid-mediated quinolone resistance (PMQR) genes were detected in 12 isolates. Mutations at the Ser-83→Leu and/or Asp-87→Asn in the gyrA gene were detected as well as mutations at the Ser-80→Ile in parC. An E. coli microarray (Maxivirulence V 3.1) was used to characterize the virulence and antimicrobial resistance genes profiles of the fluoroquinolone-resistant isolates. Antimicrobial resistance genes such as blaTEM, sulI, sulII, dhfrIX, aph3 (strA), and tet (B) as well as integrons were found in fluoroquinolone (FQ) resistance E. coli strains. The presence of potential pathogenic E. coli and antibiotic resistance in San Pedro River such as FQ resistant E. coli could pose a potential threat to human and animal

  10. Mejora de los procesos de beneficio y extracción de minerales auroargentíferos del asentamiento minero de San Pedro Frío, Colombia

    Directory of Open Access Journals (Sweden)

    Yáñez Traslaviña, J. J.

    2005-04-01

    Full Text Available The San Pedro Frio district mining, Colombia, is a rich region producing gold-silver ores. Nowadays, the extraction processes used are amalgamation, percolation cyanidation and precipitation with zinc wood. Due to the ignorance of the ore characteristics, gold and silver treatment processes are inadequate and not efficient In addition the inappropriate use of mercury and cyanide cause environmental contamination. In this research the ore characterization was carried out obtaining fundamental parameters for the technical selection of more efficient gold and silver extraction processes. Experimental work was addressed to the study of both processes the agitation cyanidation and the adsorption on activated carbon in pulp. As a final result proposed a flowsheet to improve the precious metals recovery and reduce the environment contamination.

    El asentamiento minero San Pedro Frío, Colombia, es una región rica en minerales auroargentíferos. Actualmente, los mineros de la región emplean procesos de tratamiento como amalgamación, cianuración por percolación y precipitación con viruta de zinc. Debido al desconocimiento de las características del mineral que allí se explota, los procesos de beneficio y tratamiento de oro y plata resultan inadecuados y poco eficientes, ocasionando, además, contaminación ambiental por el uso inapropiado del mercurio y cianuro. En este trabajo se realizó la caracterización del mineral obteniéndose parámetros fundamentales para la selección técnica de los procesos de extracción y recuperación de oro y de plata. El trabajo experimental se orientó al estudio de los procesos de cianuración por agitación y de adsorción con carbón activado en pulpa. Como resultado final, se presentó una propuesta de tratamiento para mejorar la recuperación de los metales preciosos y disminuir los niveles de contaminación ambiental

  11. Diversidad florística y conservación del Santuario Regional de Piura Manglares San Pedro de Vice-Sechura

    Directory of Open Access Journals (Sweden)

    Manuel Charcape-Ravelo

    2013-05-01

    Full Text Available El presente trabajo se llevó a cabo con la finalidad de conocer la composición de las fanerógamas del Santuario Regional de Piura Manglares San Pedro de Vice-Sechura. Su importancia radica en que es el manglar más austral del Pacífico de Sudamérica. Dicho trabajo fue realizado desde abril del 2000 hasta febrero del 2004. Para la realización del presente estudio se realizaron visitas periódicas cada dos meses al lugar, se colectaron las plantas bajo procedimientos estándar. Las muestras se determinaron en el lugar y algunas fueron llevadas al laboratorio de Botánica de la Universidad Nacional de Piura y al laboratorio de Botánica Fanerogámica de la Universidad Nacional de Trujillo para su determinación definitiva; luego, las muestras se depositaron en el herbario en formación de la Universidad Nacional de Piura. El manglar consiste en primer lugar de árboles y arbustos de Avicennia germinans (L. L. (Verbenaceae «mangle prieto». En el presente inventario se documentan un total de 44 especies de fanerógamas correspondiendo a 36 géneros en 21 familias para el manglar.

  12. Evaluación de la gestión en el Parque Regional de las Salinas y Arenales de San Pedro del Pinatar (Murcia

    Directory of Open Access Journals (Sweden)

    Gustavo A. Ballesteros Pelegrín

    2014-01-01

    Full Text Available El Parque Regional de las Salinas y Arenales de San Pedro del Pinatar es un territorio multifuncional desde el punto de vista social, económico y ambiental, donde es imposible separar y, por tanto gestionar de forma independiente, las tramas paisajísticas y ecológicas de las tramas socioeconómicas. Para su gestión, la Administración se apoya en el Plan de Ordenación de los Recursos Naturales aprobado en 1995, que sin embargo ha sido ejecutado en el 50 % de su articulado. Se desarrollan diversas iniciativas de conservación de fauna y flora silvestre, recogida de residuos sólidos, una adecuada información al visitante y mejora del conocimiento de los diferentes elementos de los espacios protegido. Sin embargo la participación social es escasa, la Junta Rectora se ha reunido en solo cuatro ocasiones, la última en 2001, se han producido desarrollos urbanísticos en la periferia del Parque que producen deterioro paisajístico y se han desarrollado una serie de infraestructuras que han reducido en unas 7 hectáreas la superficie protegida.

  13. El turismo rural como factor de acumulación, en la comunidad Indígena de San Pedro Atlapulco. Estado de Mexico

    Directory of Open Access Journals (Sweden)

    Dulce Enríquez Pérez

    2017-01-01

    Full Text Available El presente artículo aborda el tema de organización comunal, turismo comunitario y formas de acumulación para comprender la realidad de San Pedro Atlapulco. Esta población de origen indígena, está localizada Estado de México y sobresale entre muchas otras por conservar hasta el día de hoy el régimen comunal. Su privilegiada localización geográfica, la hacen susceptible a una riqueza extraordinaria natural de paisajes alpinos, esplendorosos valles y una abundancia de recursos acuíferos que le permitieron a sus habitantes incursionar en el turismo, en las primeras décadas del siglo pasado. El desarrollo de las actividades recreativas activó la economía local para la comunidad pero también rompió los esquemas tradicionales de las actividades, ya que el turismo se delineo bajo una dinámica individual de las familias campesinas, propiciando paulatinamente formas de acumulación desde el ceno de la comunidad que ponen en riesgo su organización y el futuro de sus recursos ante el actual contexto neoliberal.

  14. Assessing Hydrologic Impacts of Future Land Cover Change Scenarios in the South Platte River Basin (CO, WY, & NE) and the San Pedro River Basin (U.S./Mexico).

    Science.gov (United States)

    Barlow, J. E.; Burns, I. S.; Guertin, D. P.; Kepner, W. G.; Goodrich, D. C.

    2016-12-01

    Long-term land-use and land cover change and their associated impacts pose critical challenges to sustaining vital hydrological ecosystem services for future generations. In this study, a methodology to characterize hydrologic impacts from future urban growth through time that was developed and applied on the San Pedro River Basin was expanded and utilized on the South Platte River Basin as well. Future urban growth is represented by housing density maps generated in decadal intervals from 2010 to 2100, produced by the U.S. Environmental Protection Agency (EPA) Integrated Climate and Land-Use Scenarios (ICLUS) project. ICLUS developed future housing density maps by adapting the Intergovernmental Panel on Climate Change (IPCC) Special Report on Emissions Scenarios (SRES) social, economic, and demographic storylines to the conterminous United States. To characterize hydrologic impacts from future growth, the housing density maps were reclassified to National Land Cover Database (NLCD) 2006 land cover classes and used to parameterize the Soil and Water Assessment Tool (SWAT) using the Automated Geospatial Watershed Assessment (AGWA) tool. The objectives of this project were to 1) develop and implement a methodology for adapting the ICLUS data for use in AGWA as an approach to evaluate impacts of development on water-quantity and -quality, 2) present, evaluate, and compare results from scenarios for watersheds in two different geographic and climatic regions, 3) determine watershed specific implications of this type of future land cover change analysis.

  15. Los componentes de la variación intramuestral en la población prehistórica de San Pedro de Atacama, Chile

    Directory of Open Access Journals (Sweden)

    Varela, Héctor Hugo

    1996-01-01

    Full Text Available Se presenta una síntesis de una serie de experiencias realizadas con el fin de analizar el efecto del dimorfismo sexual, la variación etaria, la deformación artificial y la variación cronológica sobre la morfología craneana de la población prehistórica de San Pedro de Atacama. La muestra está constituída por 120 cráneos de ambos sexos, de edades adulto, maduro y senil, deformados y no deformados artificialmente, pertenecientes a cementerios que cubren cuatro fases culturales del Periodo Agroalfarero (500aC-1500dC. Los ejemplares masculinos presentaron valores medios mayores que los femeninos en la mayoría de las variables analizadas. La influencia de los restantes factores se manifestó en un tercio de las medidas craneométricas. Entre las clases adulto y maduro se comprobó un incremento significativo de los promedios. El efecto de la deformación artificial se destaca principalmente por alteraciones en el crecimiento de la bóveda y, en menor medida, en la cara y en la base del cráneo. Un hallazgo de importancia lo constituye la existencia de variación cronológica indicando cambios en la estructura de la población en el período estudiado.

  16. Incorporación al turismo y transformación del habitus en la mujer campesina de San Pedro Atlapulco, México

    Directory of Open Access Journals (Sweden)

    Carlos Pérez-Ramírez

    2012-11-01

    Full Text Available Normal 0 21 false false false PT-BR X-NONE X-NONE O objetivo deste trabalho é analisar as mudanças no habitus das mulheres rurais na comunidade de San Pedro Atlapulco, localizado no Estado do México (México, com base na inclusão de serviços turísticos, a fim de determinar o impacto sobre a dinâmica e conformação da unidade familiar, o espaço coletivo e até mesmo sua relação com o exterior. A pesquisa é baseada na teoria do habitus proposta por Bourdieu (1988, contrastando a situação do habitus de mulheres antes e depois do desenvolvimento do turismo rural. Conclui-se que, apesar das mudanças que a atividade turística gerou no habitus, as mulheres desta comunidade preserva a sua organização social através do trabalho, as ações de legado, e um interesse coletivo para melhorar suas condições de vida.

  17. Dieta de murciélagos filostómidos del valle de Kosñipata, San Pedro, Cusco - Perú

    Directory of Open Access Journals (Sweden)

    Rossana Maguiña

    2012-11-01

    Full Text Available En el presente estudio se evaluó la dieta de murciélagos filostómidos de los bosques montanos del valle de Kosñipata (San Pedro, Cusco. Las especies evaluadas pertenecieron a los géneros Carollia, Sturnira y Anoura. Se analizó la dieta en base a la presencia de polen y semillas en muestras fecales. Se realizó un análisis de la importancia de las plantas consumidas, la amplitud del nicho alimenticio y el nivel de superposición del nicho alimenticio. Los resultados mostraron que la dieta de los murciélagos está compuesta en su mayoría por frutos y néctar-polen de las plantas. Los principales recursos registrados pertenecieron a los géneros Piper (registrado en 23,08% de las muestras, Cecropia (en 21,15% y Abutilon (en 13,46%, los cuales fueron los recursos más importantes para la comunidad de murciélagos evaluada. La amplitud de nicho alimenticio para las 6 especies analizadas indicó que son especialistas en su dieta en el área de estudio. Por otro lado, los mayores niveles de superposición de nicho alimenticio ocurre entre las especies C. brevicauda, C. perspicillata y S. erythromos.

  18. Spatial digital database of the geologic map of Catalina Core Complex and San Pedro Trough, Pima, Pinal, Gila, Graham, and Cochise counties, Arizona

    Science.gov (United States)

    Dickinson, William R.; digital database by Hirschberg, Douglas M.; Pitts, G. Stephen; Bolm, Karen S.

    2002-01-01

    The geologic map of Catalina Core Complex and San Pedro Trough by Dickinson (1992) was digitized for input into a geographic information system (GIS) by the U.S. Geological Survey staff and contractors in 2000-2001. This digital geospatial database is one of many being created by the U.S. Geological Survey as an ongoing effort to provide geologic information in a geographic information system (GIS) for use in spatial analysis. The resulting digital geologic map database data can be queried in many ways to produce a variety of geologic maps and derivative products. Digital base map data (topography, roads, towns, rivers, lakes, and so forth) are not included; they may be obtained from a variety of commercial and government sources. This database is not meant to be used or displayed at any scale larger than 1:125,000 (for example, 1:100,000 or 1:24,000). The digital geologic map plot files that are provided herein are representations of the database. The map area is located in southern Arizona. This report lists the geologic map units, the methods used to convert the geologic map data into a digital format, the ArcInfo GIS file structures and relationships, and explains how to download the digital files from the U.S. Geological Survey public access World Wide Web site on the Internet. The manuscript and digital data review by Lorre Moyer (USGS) is greatly appreciated.

  19. Factores de riesgo relacionados al uso de drogas ilegales: perspectiva crítica de familiares y personas cercanas en un centro de salud público en San Pedro Sula, Honduras Fatores de risco relacionados ao uso de drogas ilegais, perspectiva crítica de familiares e pessoas próximas, em um centro da saúde público em San Pedro Sula, Honduras Risk factors related to the use of illegal drugs: the critial perspective of drug users' relatives and acquaintances at a public health center in San Pedro Sula, Honduras

    OpenAIRE

    Gladys Magdalena Rodríguez Funes; Bruna Brands; Edward Adlaf; Norman Giesbrecht; Laura Simich; Maria da Gloria Miotto Wright

    2009-01-01

    En este estudio, se presentan datos cuantitativos del estudio multicéntrico, multimétodos, de corte transversal realizado en un centro de salud público en San Pedro Sula, en Honduras. Su objetivo es describir la perspectiva crítica que tienen los familiares o personas, que se consideran afectadas por tener a alguien cercano que usa o ha usado drogas ilegales, con relación a factores de riesgo. Los datos se obtuvieron mediante una encuesta con 100 entrevistados. La mayor parte de las personas ...

  20. Institutions and Societal Impacts of Climate in the Lower Colorado and San Pedro Basins of the U.S.-Mexico Border Region

    Science.gov (United States)

    Varady, R. G.; Wilder, M.; Morehouse, B. J.; Garfin, G. M.

    2007-05-01

    The U.S. Southwest and Mexico border region feature two prominent river basins, the Colorado and Rio Grande, and ecologically important sub-basins such as the San Pedro. The area within which these transboundary basins lie is characterized by overall aridity and high climatic variability over seasonal to decadal and longer time scales. Throughout human occupation, numerous and diverse strategies for buffering climate impacts have emerged. The most notable response has been an increasingly complex system of institutions and structures designed to buffer water scarcity. The Colorado River Compact, and the laws governing allocation of waters from the Rio Grande River, together with the dams, hydropower generators, canals and other engineered features, represent two of the most complex systems. Drought nevertheless remains a looming specter across much of the binational border region. Institutional mechanisms for responding to drought range from awareness-raising and capacity-building efforts, to implementation of formal drought plans, to storing water to make up for deficits, and water conservation rules that become increasingly stringent as drought intensifies. A number of formal and informal binational institutions operate in the region. Some are venerable, like the century-old International Boundary and Water Commission (IBWC) and its Mexican counterpart the Comision Internacional de Limites y Agua (CILA). Others, like the Border Environment Cooperation Commission and the North American Development Bank, were created in the mid-1990s with the North American Free Trade Agreement. These institutions, both domestic and transnational, operate in a complex binational, bicultural environment with contrasting legal and administrative traditions. Under such constraints, they manage water resources and ecosystems and attempt to improve water and sanitation infrastructure in the context of deep and extended drought. But in spite of their efforts, society and natural habitat

  1. La sucesión paleozoica en el sinforme de la Sierra de San Pedro (provincias de Cáceres y Badajoz, SO de España

    Directory of Open Access Journals (Sweden)

    Soldevila Bartolí, J.

    1992-12-01

    Full Text Available The Sierra of San Pedro forms a Paleozoic synform, located in the southern part of the Central Iberian zone (Iberian Massif. The thickness of the Paleozoic sequence in the synform can be evaluated at 2,800-3,000 m. Its base is in general formed by a 5-40 m thick quartzite unit, equivalent to the Armorican Quartzite (Arenig, resting unconformable on the Precambrian. However, a discontinuous conglomerate level, attributed to the basal Arenig, can locally be found underlying the quartzite. Above the quartzite, the sequence is essentially compound of an alternation of predominantly quartzite, sandstone and slate units. This alternation allows the sequence to be subdivided into several distinct lithological units. Towards the top, carbonate and volcanic levels are found, interlayered in the predominantly terrigenous sequence. Most of the lithostratigraphical units have provided fairly abundant faunas and could therefore be dated. The paleontological evidence shows that the sequence is continuous from the Lower Ordovician to the Lower Carboniferous, with the exception of a probable hiatus comprising the Middle Devonian. Upper Carboniferous conglomerates and sandstones also occur in the area.El sinforme de la Sierra de San Pedro, situado en la parte meridional de la Zona Centroibérica, está formado por materiales paleozoicos cuyo contacto con los materiales precámbricos que le rodean es en clara discordancia angular. La parte inferior de la sucesión paleozoica está formada por un tramo cuarcítico de 5-40 m de espesor y edad Arenig (Cuarcita Armoricana bajo la cual aparecen muy localmente tramos conglomeráticos atribuibles al Arenig basal. El resto de la sucesión paleozoica está constituida esencialmente por materiales detríticos formados por cuarcitas, areniscas y pizarras que se encuentran alternando en distintos niveles. No obstante, hacia la parte alta de la sucesión aparecen también materiales carbonatados y rocas volcánicas. El

  2. New Contributions to the Geomagnetic Instability Time Scale: Paleomagnetic study of Tequila and Ceboruco-San Pedro-Amado Nervo Volcanic Fields (Trans Mexican Volcanic Belt)

    Science.gov (United States)

    Rodriguez Ceja, M.; Gogichaishvili, A.; Alva-Valdivia, L.; Rosas Elguera, J.; Calvo, M.; Urrutia-Fucugauchi, J.

    2005-05-01

    The Trans-Mexican Volcanic Belt (TMVB) is one of the largest continental volcanic arcs of the North American plate. It spans about 1000 km from the Pacific to the Gulf of Mexico. Despite the abundance of thick lava sequences with quite high extrusion rates, the TMVB have been relatively little studied from a paleomagnetic point of view. Previous studies were aimed for tectonic evolution of the region rather than documenting fluctuations of Earth's magnetic field in terms of both directions and intensity. We report a detailed paleomagnetic and rock-magnetic study of Tequila and Ceboruco-San Pedro-Amado Nervo volcanic fields. 350 oriented samples belonging to 31 independent cooling units were collected. All these sites were previously dated by means of the state-of-the-art 40Ar-39Ar geochronological method and span from 1.1 Ma to 2 Ky. Rock-magnetic experiments which included continuous susceptibility, isothermal remanence acquisition and hysteresis measurements point to simple magnetic mineralogy. In most of cases, the remanence is carried by Ti-poor titanomagnetite of pseudo-single-domain magnetic structure. The paleodirections of the flow dated as 819±25 ka correspond to a VGP latitude of 18° N. This anomalous field behaviour apparently recorded prior to the Matuyama-Brunhes reversal may coincide with the geomagnetic event, defined as M-B precursor. Two independent lava flows, dated as 623±91 and 614±16 ka respectively, yield reverse paleodirections and one lava flow dated as 690±29 yields transitional paleodirections. It is possible that these lavas erupted during the worldwide observable Big Lost or Delta events.

  3. Autoestima y agresividad en estudiantes de quinto grado de educación primaria de la institución educativa estatal "Pedro Adolfo Labarthe", distrito La Victoria, UGEL 03 San Miguel 2015.

    OpenAIRE

    Pariona Martínez, Magaly

    2015-01-01

    Este estudio responde al objeto determinar si existe relación significativa de la autoestima con la agresividad en estudiantes de quinto grado de educación primaria de la Institución Educativa estatal “Pedro Adolfo Labarthe”, distrito la Victoria, UGEL 03 San Miguel, 2015. El interés de la presente investigación es establecer la relación entre los factores emocionales – particularmente la autoestima- y la agresividad en estudiantes de quinto grado de educación primaria, describir cómo ha sido...

  4. La vida en torno al café: marginación social de pequeños productores en San Pedro Cafetitlán, Oaxaca, México

    OpenAIRE

    Israel Morales Becerra

    2013-01-01

    Se presenta una descripción etnográfica del trabajo de campo realizado en San Pedro Cafetitlán, Oaxaca, México sobre la situación de marginación social derivada de la implementación del modelo económico neoliberal; se hace una interpretación del significado que tiene el cultivo del café en la vida de los pobladores. Destaca el hecho de que las generaciones mayores de 60 años aun valoran el recurso, tienen identidad con la tierra y esperanzas en su café; sin embargo, para las nuevas gen...

  5. Factores de riesgo relacionados al uso de drogas ilegales: perspectiva crítica de familiares y personas cercanas en un centro de salud público en San Pedro Sula, Honduras

    OpenAIRE

    Rodríguez Funes, Gladys Magdalena; Brands, Bruna; Adlaf,Edward; Giesbrecht, Norman; SIMICH, Laura; Wright,Maria da Gloria Miotto

    2009-01-01

    En este estudio, se presentan datos cuantitativos del estudio multicéntrico, multimétodos, de corte transversal realizado en un centro de salud público en San Pedro Sula, en Honduras. Su objetivo es describir la perspectiva crítica que tienen los familiares o personas, que se consideran afectadas por tener a alguien cercano que usa o ha usado drogas ilegales, con relación a factores de riesgo. Los datos se obtuvieron mediante una encuesta con 100 entrevistados. La mayor parte de las personas ...

  6. Y el claustro se abrió al siglo: Pedro Zulen y el Boletín Bibliográfico de la Biblioteca de San Marcos (1923-1924Y el claustro se abrió al siglo: Pedro Zulen y el Boletín Bibliográfico de la Biblioteca de San Marcos (1923-1924

    Directory of Open Access Journals (Sweden)

    Alberto Loza Nehmad

    2011-05-01

    Full Text Available En 1923, Pedro Zulen (1898-1925 fundó el Boletín bibliográfico de la Bibliotecade la Universidad Nacional Mayor de San Marcos. La publicación delboletín fue resultado de la modernización de la biblioteca impulsada por elrector Manuel Vicente Villarán y conducida por Zulen quien publicó losquince números del primer volumen, que se cierra en 1924. En esos dosaños volcó su talento intelectual y editorial en el boletín e hizo de él unapublicación académica reconocida a nivel internacional. En esa tarea, él sedesempeñó como el puente entre dos generaciones. Dirigió, sobre todo, aun grupo de estudiantes que había salido de la adolescencia durante elmovimiento de la Reforma Universitaria. Ellos se consolidaron intelectualmente,como colectivo, en las tareas de la publicación del Boletín. Estegrupo, de la Generación del Centenario, tuvo después un destacado papelen la vida intelectual peruana del siglo XX.

  7. Análisis de vulnerabilidad ambiental de la cuenca alta del río San Pedro, estado Miranda, Venezuela

    Directory of Open Access Journals (Sweden)

    Haideé Coromoto Marín

    2017-12-01

    Full Text Available Se caracterizó la vulnerabilidad ambiental por inundación y desplazamiento en comunidades asentadas en la Cuenca alta del río San Pedro, municipio Guaicaipuro, estado Miranda; Venezuela usando SIG. El área de estudio se dividió en dos zonas, una ligeramente intervenida (A y otra fuertemente intervenida (B, para obtener los mapas temáticos usados como indicadores, los cuales se estandarizaron mediante la técnica de re-clasificación asignándoles valores numéricos en una escala del 1 al 5. Los resultados muestran que la vulnerabilidad por inundación en la subcuenca siguió la siguiente tendencia: clase media (3 33.75% > clase Baja (2 31.91% > clase muy Baja (1 26.86% > clase Alta (4 6.12% > clase muy alta (5 1.37%, no obstante las clases alta y muy alta se corresponde con comunidades cercanas al río, caracterizadas por la presencia de desarrollos urbanos, alta actividad agrícola, sugiriendo un alto riesgo por inundación. La distribución espacial de la vulnerabilidad por desplazamiento sugiere que predomina la clase media (3 y baja (2, las cuales representan el 50.58% y 36.25% respectivamente, mientras que el resto de las clase como alta (4, muy baja (1 y muy alta (5 mostraron porcentajes de 9.37, 3.29 y 0.41 respectivamente. Las clases de vulnerabilidad alta y muy alta están localizadas en el área de mayor intervención (Zona B, con un patrón muy irregular asociado a suelos con altas pendientes (>30% y manejo de suelo con cultivos pocos protectores como las hortalizas, favoreciendo procesos de degradación e incidiendo en la sustentabilidad de la zona. Los resultados obtenidos han servido para discriminar cuales comunidades son más vulnerables y establecer prioridades en cuanto a la intervención para minimizar los impactos ambientales.

  8. Improving the Flash Flood Frequency Analysis using dendrogeomorphological evidences in the Arenal River crossing Arenas de San Pedro Village (Spanish Central System)

    Science.gov (United States)

    Ruiz-Villanueva, V.; Ballesteros, J. A.; Díez-Herrero, A.; Bodoque, J. M.

    2009-04-01

    The flash flood frequency analysis in mountainous catchments presents specific scientific challenges. One of the challenges is the relevant gradient in precipitation intensity with altitude. Another challenge is the lack of information from rainfall or discharge gauge stations or from documentary sources. Dendrogeomorphology studies the response in the wood growth pattern and the botanical signs on the trees affected by geomorphological processes. With regard to the flood frequency, the dendrogeomorphological evidences bring forward valuable infomation about single past events (with annual or even seasonal precision) and their occurrence periodicity. The main macro-evidence that we can find in the tree trunk is a stem scar originated by a wound in the bark of the tree. When the tree grows, this wound remains reflected in the tree ring sequence. The best way to analyze the tree ring sequence is by using a complete section of the trunk, this couldn't be possible unless the tree is cut down. Due to the unfeasibility of cutting down the trees, in Dendrogeomorphology is enough to obtain an increment core, using a Pressler borer. Nevertheless, this study has been based on complete stem sections analysis facilitated for the felling works in the riverine vegetation in the Arenal River, carried out by the Tagus River Water Authority. These felling works have allowed us to obtain sections and to analyze the stump of the tree in situ. On this way, 100 samples of Alnus glutinosa and Fraxinus angustifolia located by the river along the Arenal River crossing Arenas de San Pedro Village (Ávila, northern slopes of the Gredos Mountain Range in the Spanish Central System) have been analyzed. This village is known for its historical problems of flood during extreme events. A meticulous fieldwork has been carried out. Every sample was analyzed locating its geomorphological position, the distance to the riverbed and the height of the stump in which the evidences were observed. Using a

  9. Evaluation of the importance of clay confining units on groundwaterflow in alluvial basins using solute and isotope tracers: the case of Middle San Pedro Basin in southeastern Arizona (USA)

    Science.gov (United States)

    Hopkins, Candice B.; McIntosh, Jennifer C.; Eastoe, Chris; Dickinson, Jesse E.; Meixner, Thomas

    2014-01-01

    As groundwater becomes an increasingly important water resource worldwide, it is essential to understand how local geology affects groundwater quality, flowpaths and residence times. This study utilized multiple tracers to improve conceptual and numerical models of groundwater flow in the Middle San Pedro Basin in southeastern Arizona (USA) by determining recharge areas, compartmentalization of water sources, flowpaths and residence times. Ninety-five groundwater and surface-water samples were analyzed for major ion chemistry (water type and Ca/Sr ratios) and stable (18O, 2H, 13C) and radiogenic (3H, 14C) isotopes, and resulting data were used in conjunction with hydrogeologic information (e.g. hydraulic head and hydrostratigraphy). Results show that recent recharge (solute and isotope geochemistries between the lower and upper basin fill aquifers show the importance of a clay confining unit on groundwater flow in the basin, which minimizes vertical groundwater movement.

  10. Analyse des propriétés hydrodynamiques des aquifères fissurés de la région de San-Pedro (Sud-Ouest de la Côte d’Ivoire

    Directory of Open Access Journals (Sweden)

    De-Lasme, O. Z.

    2012-12-01

    Full Text Available San-Pedro area is localized in south-western Côte d’Ivoire and covers a surface of 6912 km2. Wa t e r resources exploited in this area are constituted of surface waters and groundwater of weathered and fissured aquifers. The aims of this study are to analyze hydrodynamic properties of fissured aquifers of San-Pedro on statistical and geostatistical viewpoints for a better knowledge and management of groundwater resources. Data base includes 110 drillings tapping fissured aquifers. Transmissivity was calculated by interpreting of pumping tests with classical methods. Specific capacity was calculated at the end of the third step for all drillings after correction of drawdowns. Transmissivity and specific capacity values oscillate between 1,27.10-6 and 8,59.10-4 m2.s-1 and between 1,09.10-2 m2.h-1 et 13,2 m2.h-1, respectively. These two parameters span three orders of magnitude showing the strong heterogeneity of the medium. An empirical relationship was established between transmissivity and specific capacity of San-Pedro area. This relationship can be used to determine transmissivity in the sectors where this data is lacking. Variogram of transmissivity is characterized by a double structuring. Transmissivity assessment by kriging is satisfactory, observed and estimated values are comparable. The findings obtained in this study lead to a better understanding of hydrogeological properties of south-western Côte d’Ivoire.

    [fr] La région de San-Pedro est localisée dans le sud-ouest de la Côte d’Ivoire et couvre une superficie de 6912 km2. Les ressources en eau exploitées dans cette région sont constituées des eaux de surface et des eaux souterraines des aquifères des altérites et de fissures du socle précambrien. La présente étude a pour objectif d’analyser les propriétés hydrodynamiques des aquif

  11. Factores de riesgo relacionados al uso de drogas ilegales: perspectiva crítica de familiares y personas cercanas en un centro de salud público en San Pedro Sula, Honduras Fatores de risco relacionados ao uso de drogas ilegais, perspectiva crítica de familiares e pessoas próximas, em um centro da saúde público em San Pedro Sula, Honduras Risk factors related to the use of illegal drugs: the critial perspective of drug users' relatives and acquaintances at a public health center in San Pedro Sula, Honduras

    Directory of Open Access Journals (Sweden)

    Gladys Magdalena Rodríguez Funes

    2009-01-01

    Full Text Available En este estudio, se presentan datos cuantitativos del estudio multicéntrico, multimétodos, de corte transversal realizado en un centro de salud público en San Pedro Sula, en Honduras. Su objetivo es describir la perspectiva crítica que tienen los familiares o personas, que se consideran afectadas por tener a alguien cercano que usa o ha usado drogas ilegales, con relación a factores de riesgo. Los datos se obtuvieron mediante una encuesta con 100 entrevistados. La mayor parte de las personas informantes eran mujeres pobres con baja escolaridad. Los consumidores eran en su mayoría hombres con edad promedio de 23,3 años. La droga más usada fue la marihuana (78% seguida de crack/cocaína (72%, pegamento/inhalantes (27%, alucinógenos (éxtasis/LSD (3%, anfetaminas/estimulantes (1% y heroína (1%. Los factores de riesgo identificados fueron la experiencia previa con alcohol/tabaco, el tener amigos/amigas que usan drogas, la falta de conocimiento, la baja autoestima , la edad, entre otros factores personales, familiares y sociales. Se concluye que es necesario fortalecer las medidas de prevención y protección.São apresentados, aqui, dados quantitativos de um estudo multicêntrico, multimétodos, de corte transversal, realizado em um centro de saúde pública em San Pedro Sula, Honduras. O objetivo foi descrever a perspectiva crítica dos membros da família ou pessoas que se sentem afetadas por terem alguém próximo que usa ou usou drogas ilegais, em relação aos fatores de risco. Os dados foram coletados através de questionário aplicado em 100 indivíduos. A maioria era composta por mulheres pobres, com pouca escolaridade. Os consumidores eram majoritariamente varões, com idade média de 23,3 anos. A droga mais utilizada foi a maconha (78%, seguida por crack/cocaína (72%, cola/inalantes (27%, alucinógenos (ecstasy/LSD (3%, anfetaminas/estimulantes (1%, heroína (1%. Entre os fatores de risco identificados estão: experi

  12. La vida en torno al café: marginación social de pequeños productores en San Pedro Cafetitlán, Oaxaca, México

    Directory of Open Access Journals (Sweden)

    Israel Morales Becerra

    2013-03-01

    Full Text Available Se presenta una descripción etnográfica del trabajo de campo realizado en San Pedro Cafetitlán, Oaxaca, México sobre la situación de marginación social derivada de la implementación del modelo económico neoliberal; se hace una interpretación del significado que tiene el cultivo del café en la vida de los pobladores. Destaca el hecho de que las generaciones mayores de 60 años aun valoran el recurso, tienen identidad con la tierra y esperanzas en su café; sin embargo, para las nuevas generaciones el café ha dejado de ser un recurso importante debido a que no es posible subsistir de dicho cultivo, por lo que muchos han preferido vender sus tierras y emigrar. La  desintegración social causada por el fenómeno de la migración ha puesto en riesgo la conservación de costumbres y tradiciones culturales generadas a principios del siglo veinte en esta  comunidad

  13. Ocupantes espontáneos y derechos por la tierra en la formación de “pueblos de españoles” (Rincón de San Pedro, Buenos Aires, 1740-1860

    Directory of Open Access Journals (Sweden)

    Mariana Canedo

    2015-01-01

    Full Text Available Durante el siglo XVIII, se multiplicó la presencia de “pueblos de espa-ñoles” y villas en la frontera sur hispanoamericana. El protagonismo de ocupantes rurales en la formación de “pueblos de españoles” fue más frecuente en la campaña de Buenos Aires que en otras jurisdicciones, aunque poco se conoce sobre su proceder. El objetivo del artículo fue analizar las características de los ocupantes rurales y el rango de acción que tuvieron para solicitar el reconocimiento legal de terrenos para la formación de un pueblo en la campaña de Buenos Aires durante el siglo XVIII y parte del XIX. El análisis del caso del pueblo de San Pedro nos permitió profundizar la situación de los “ocupantes” y abrir varios inte-rrogantes sobre la regulación de los derechos por la tierra, particularmen-te sobre los pueblos y villas, en un período que suele estar vinculado a transformaciones en los derechos y en las relaciones de poder ejercidas en su puesta en práctica.

  14. Além da lama e do lixo: movimentos de escolarização em São Pedro, Vitória/ES (1977-2007 Beyond the mud and the waste: schooling movements in San Pedro, Victoria/ES (1977-2007

    Directory of Open Access Journals (Sweden)

    Kezia Rodrigues Nunes

    2012-03-01

    Full Text Available Discute o processo histórico de escolarização da infância no bairro São Pedro I, em Vitória/ES. Relaciona-o com o movimento de constituição da região na década de 1970. Toma como lócus o CMEI da Amizade, instituição que acompanha a primeira referência de espaço educativo. Privilegia como fonte o relato dos sujeitos residentes no bairro, expressos em dois livros sobre o movimento de constituição da região, escritos por uma moradora, e uma obra produzida por pesquisadores, moradores e a Prefeitura de Vitória. Também destaca as narrativas de uma cozinheira e de uma auxiliar de serviços gerais, profissionais da instituição pesquisada. As fontes são analisadas como "testemunhos", como conhecimento através de "vestígios". Procura compreender os "usos táticos" e "estratégicos" praticados pelos sujeitos na mobilização popular, na organização das moradias e instituições educativas, bem como os reflexos dessa experiência para os que permanecem no CMEI educando crianças, atualmente.This paper discusses the historical process of schooling in childhood in the neighborhood of San Pedro I, in Victoria, E.S. It looks at the constitutional movement of the 1970s in the (E.S. region. As its focal point, it takes "CMEI da Amizade", an institution that follows the first reference to educational space. It has as a privileged source, the accounts of residents of the neighborhood. These subjects' accounts, are expressed in two books on the region's constitutional movement, one written by a resident, and another, a work produced by researchers, residents and the local government of Victoria. It also highlights the narratives of a cook and a general services assistant, professionals of the institution being investigated. The sources are analyzed as witness accounts providing remnants of knowledge and therefore comparative data. What it seeks to understand are the "practical strategies" and "tactics" employed by the subjects in these

  15. El agua y los territorios hídricos en la Región Metropolitana de Santiago de Chile. Casos de estudio: Tiltil, Valle de Mallarauco y San Pedro de Melipilla

    Directory of Open Access Journals (Sweden)

    Tesser Obregón, Claudio Ernesto Esteban

    2013-06-01

    Full Text Available The rural area of the Santiago Metropolitan Region is a combination of natural, social, economic and technical factors that give origin to several territories. If we consider those in which water resources play a significant role in carrying out agricultural activity, several different «water territories» can be identified in the Tiltil, Valle de Mallarauco and San Pedro de Melipilla areas. In these cases the study allowed us to shed light upon and discuss several important points regarding the territorial approach to water resources and water management in a model that favors the actions of private parties, such as: the extension of the agricultural use of the water resources, the conflicts and problems over its control and the resulting water territories that have come about as a result of the various assessments of a liberal management system. This has been done with the intention of contributing, from a Geographical point of view, thoughts geared towards achieving a comprehensive and sustainable management of the water resources in Chile.El espacio rural de la Región Metropolitana de Santiago de Chile es una combinación de factores naturales, sociales, económicos y técnicos que dan origen a diversos territorios. Si consideramos aquellos donde el recurso hídrico tiene un papel predominante en el desarrollo de las actividades agrícolas, se pueden identificar distintos «territorios hídricos» en las áreas de Tiltil, Valle de Mallarauco y San Pedro de Melipilla. El estudio de estos casos permitió poner en evidencia y discutir un cierto número de puntos importantes concernientes al enfoque territorial de los recursos hídricos y de la gestión del agua en un modelo que privilegia la acción de los privados, tales como: la dimensión espacial del uso agrícola de los recursos hídricos, los conflictos y problemas por su control y los consecuentes territorios hídricos que han surgido como resultado de diversas valorizaciones de un

  16. El impacto de la desecación de la laguna de Lerma en la gastronomía lacustre de San Pedro Tultepec de Quiroga, Estado de México

    Directory of Open Access Journals (Sweden)

    Felipe Carlos Viesca González

    2011-01-01

    Full Text Available El objetivo de este trabajo es caracterizar la gastronomía lacustre en el Alto Lerma, prevaleciente antes y después de la desecación de la Laguna de Lerma, específicamente la de San Pedro Tultepec de Quiroga municipio de Lerma, en el Estado de México. Mediante la aplicación de la técnica etnográfica en la realización de la investigación de campo, se identificaron y localizaron a 30 personas adultas que aún entran a la laguna de Chimaliapan o Lerma, o que tienen conocimiento sobre los ingredientes lacustres y las preparaciones culinarias elaboradas con ellos. Además se realizaron visitas a los mercados locales e incursiones en la laguna y áreas aledañas con la guía de lugareños conocedores del entorno, con el fin de obtener información sobre estos productos. Se encontró que todavía se recolectan especies vegetales como nopales, hongos, papas de agua o apacloles y quelites, entre ellos berros o tiernitos y quintoniles. Asimismo, se aprovechan especies animales como patos, carpas, atepocates, ranas, acociles y ajolotes. Menos del 1% de la población estudiada aún elabora platillos basados en ingredientes extraídos de la laguna. Se preparan tamales de pescado, rana o carpa, acociles, hueva de carpa, carpas y patos de diversas maneras, chile relleno de támbulas y atepocates, y ranas empanizadas o fritas. Con base en lo anterior, se concluye, que a pesar de estar contaminada, todavía se extrae de la laguna de Chimaliapan una gran variedad de flora y fauna que se emplea para la alimentación, lo cual indica que estos recursos bióticos son una importante fuente para muchas familias, y que tienen un "buen potencial" de aprovechamiento.

  17. 78 FR 21403 - Notice of Inventory Completion: San Francisco State University NAGPRA Program, San Francisco, CA

    Science.gov (United States)

    2013-04-10

    ... NAGPRA Program, c/o Department of Anthropology, San Francisco State University, 1600 Holloway Avenue, San... conjunction with the construction of the New Don Pedro Reservoir. Site materials from the New Don Pedro...-Wuk Indians of the Tuolumne Rancheria of California. The objects are consistent with the material...

  18. Pedro Bosch Gimpera

    Directory of Open Access Journals (Sweden)

    Fernández-Posse de Arnaiz, M.ª Dolores

    2015-06-01

    Full Text Available This article presents an intellectual profile of Pedro Bosch Gimpera. It reviews his academic training, the social and intellectual environment in which he grew up, his role in the institutionalization of Catalan archaeology, his theoretical outlook, and his long-term influence even after his exile.Este artículo presenta un perfil intelectual de Pedro Bosch Gimpera. Revisa su formación académica, el ambiente social e intelectual en el que se desarrolló, su papel en la institucionalización de la arqueología catalana, su perspectiva teórica y su influencia a largo plazo incluso tras su exilio.

  19. Metodología del turismo armónico. Una propuesta de valoración de conocimientos para San Pedro Tultepec de Quiroga, Estado de México

    Directory of Open Access Journals (Sweden)

    Daniela Palmas Castrejón

    2017-01-01

    Full Text Available El objetivo de este trabajo es presentar el producto de la aplicación de la M e todolog ía del Turismo Armónico, propuesta por Palmas et al. (2014, como un Modelo Teór i co - Metodol ó gico. Método . La metodología tiene el fin de llevar a cabo una planificación turística que parta de la interrelación de los conocimientos vernáculo - racional de la s comunidades; y que permita an a lizar y gestionar al turismo armónico como alternativa para el desarrollo local bajo los atrib u tos de la sustentabilidad. La metodología, parte de las categorías de análisis: sistema complejo, elementos y subelementos sistém i cos, turismo armónico y conocimiento vernáculo - racional, las cuales permiten integrar, a partir de un diagrama de planeación ve r náculo - racional turística, las interrelaciones más fuertes entre los subsistemas biofísico (natural y antrópico (sociocultural . Como instrumentos de investigación se aplicaron 274 cuesti o narios de forma aleatoria, 45 entrevistas a profundidad a actores claves, visitas de familiarización y observación de campo constante en un período de 4 años (2009 - 2013. Resultados . El modelo p ropuesto se aplicó a partir del 2014 en San Pedro Tultepec de Quir o ga y el Humedal de Chimaliapan , con grupos pilotos de estudiantes , y se planea dar continuidad a las respuestas obtenidas con proyectos de investigación financiados. La región de estudio es tá ubicada en el municipio de Lerma, Estado de México. Entre los principales resultados, se encuentra la identificación y explicación de la problemática ambiental desde la per s pectiva de los sistemas complejos, considerando al turismo armónico como una her ramienta para prop i ciar el desarrollo local; ad e más de que esta metodología puede ser un constructo a seguir para la difusión de información de los servicios tangibles e intangibles que ofrece el Humedal a la comunidad, con el fin de promover la conciencia ción del rescate de

  20. Netivestlus Pedro Gadanhoga = An online conversation with Pedro Gadanho / Pedro Gadanho ; intervjueerinud Triin Ojari

    Index Scriptorium Estoniae

    Gadanho, Pedro

    2010-01-01

    Pedro Gadanho oma raamatusarjast "Beyond", mille mõte on eelistada arhitektuurist ja linnast kirjutamisel fiktsionaalset tehnikat, avastada eksperimentaalseid kirjutamisviise. Kirjutajateks on kriitikud ja arhitektid

  1. Figuraciones, conservación y hegemonía en el proyecto de construcción de un camino en la Reserva de Biosfera Yabotí en San Pedro, Misiones - Argentina. Periodo desde el año 2012 hasta el año 2015

    Directory of Open Access Journals (Sweden)

    Carla Antonella Cossi

    2015-01-01

    Full Text Available El presente trabajo se propone describir, desde una perspectivaantropológica, la manera en que un conjunto de agentesligados al turismo y a las áreas naturales protegidas –entre losque se encuentran organizaciones transnacionalesgubernamentales y no gubernamentales, funcionarios políticosy empresarios– se disputan el capital político, simbólico yeconómico necesario para definir los límites de la conservación.Nos aproximamos, así, a las relaciones de fuerzas que generanlas estrategias de conservación y turismo sustentable de losdiferentes sectores involucrados con el proyecto deconstrucción de un camino provincial, al interior de la Reservade Biosfera Yabotí y del Parque provincial Moconá, en SanPedro, Misiones-Argentina.

  2. ACTIVIDADES DOMÉSTICAS DURANTE LOS SIGLOS III -VIII D.C. EN EL VALLE DE POTRERILLOS (SAN IGNACIO-MENDOZA. UN ACERCAMIENTO DESDE LA OSTEOMETRÍA Y LA TECNOLOGÍA CERÁMICA Y LÍTICA / Domestic activities during the III-VIII centuries AD in Potrerillos Valley

    Directory of Open Access Journals (Sweden)

    Alejandra Valeria Gasco

    2011-12-01

    Full Text Available San Ignacio, en el Valle de Potrerillos, fue habitado durante los siglos III-VIII D.C. por grupos humanos que construyeron hornillos y ocuparon casas semi-subterráneas. Constituye uno de los escasos registros sistemáticos de contextos domésticos para el valle. Se presenta y caracteriza el sitio mediante el análisis osteométrico de camélidos, la organización de la tecnología lítica y el análisis tipológico y morfo-funcional cerámico. Las diversas actividades domésticas desarrolladas combinaron la explotación de camélidos silvestres y domésticos, además de cultígenos. Los rasgos arquitectónicos y los patrones materiales del interior de la unidad habitacional, se relacionan con una ocupación anticipada de tipo permanente. La cerámica analizada fue asignada al estilo Agrelo-Calingasta del período Agro-alfarero Temprano-Medio de la arqueología regional. El asentamiento podría insertarse en un circuito de movilidad para el aprovechamiento de diversos recursos en ambientes de altura. Además se sugiere la participación en redes de intercambio, evidenciada por la presencia de cerámica similar a la de los complejos culturales que se desarrollaron en la vertiente occidental de Los Andes y por la identificación de un morfotipo de camélido especialmente grande, propicio para la realización de caravanas.   Palabras clave: Valle de Potrerillos; Período Agro-alfarero regional; Contexto Doméstico; Camélidos silvestres y domésticos; Redes de Intercambio.   Abstract San Ignacio, in the Valley of Portrerillos was occupied during the third to eighth centuries A.D. by groups that constructed pit ovens and occupied semi-subterranean houses. It is one of the few systematically recorded domestic contexts in the valley. The site is presented and characterized through the osteometric analysis of camelids, the organization of lithic technology, and typological and morphofunctional analyses of ceramics. Diverse domestic activities

  3. Haemophilus influenzae biotype VIII.

    OpenAIRE

    Sottnek, F O; Albritton, W L

    1984-01-01

    Six Haemophilus influenzae strains could not be classified as biotypes I through VII. The strains were indole, urease, and ornithine decarboxylase negative. We propose that they be classified as biotype VIII, a previously unreported biotype.

  4. Chirp seismic-reflection data of field activity S-5-09-SC: San Pedro Basin, offshore southern California from 2009-07-06 to 2009-07-10

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This dataset includes raw and processed, high-resolution seismic-reflection data collected in 2009 to explore a possible connection between the San Diego Trough...

  5. Caracterización de los minerales auríferos de la zona minera de San Pedro Frío (Bolívar-Colombia, para la selección de los procesos de extracción

    Directory of Open Access Journals (Sweden)

    J. J. YÁNEZ TRASLAVIÑA

    2005-01-01

    Full Text Available Los procesos de beneficio y tratamiento de minerales auroargentíferos, existentes actualmente en la zona minera de San Pedro Frío (Bolívar, conllevan a sistemas poco eficientes con porcentajes de recuperación de oro no mayores al 40%. El presente trabajo es la recopilación de los resultados de análisis y caracterización de minerales auroargentíferos de dicha zona minera. Con este artículo, se intenta incentivar a los mineros a realizar un desarrollo compaginado con la universidad, ya que según los resultados obtenidos durante esta investigación, es posible lograr porcentajes de disolución de oro de hasta el 85% para los minerales de San Pedro Frío. Esta afirmación fue posible proponerla, mediante los análisis de la caracterización del mineral. Mediante la caracterización fisicoquímica del mineral, fue posible la estimación de ciertas condiciones de los procesos metalúrgicos involucrados en una posible planta de tratamiento, es así que el porcentaje de sólidos más adecuado para el manejo de los sólidos en pulpa fue del 40% en peso, la alta cantidad de minerales arcillosos podrían dificultar los procesos de separación sólido-líquido, entre otros especificaciones operativas Según la caracterización mineralógica y metalúrgica, el tamaño promedio del oro presente en el mineral, se encuentra a una granulometría menor a 75 µm, esto indica que el proceso de cianuración por agitación resultaría el más adecuado. Los resultados de la lixiviación diagnóstico, arrogaron resultados muy satisfactorios, ya que el 94% del oro en las muestras se encuentra como oro libre, lo cual podrá incidir en tiempos cortos de cianuración.

  6. El arquitecto madrileño Pedro de la Torre en Toledo y un retablo inédito localizado

    Directory of Open Access Journals (Sweden)

    Antonio José Díaz Fernández

    2014-02-01

    Full Text Available Entre las realizaciones del arquitecto barroco Pedro de la Torre para la ciudad de Toledo es posible identificar un retablo hasta ahora inédito, datado en 1653 y en el que colabora el ensamblador toledano Juan García de San Pedro, localizado hoy en la parroquia de Nambroca (Toledo, en el que se aprecian las innovaciones estructurales y ornamentales propias del lenguaje desarrollado por el artista.Among the works of the baroque architect Pedro de la Torre for the city of Toledo is possible to identify an up to now unpublished altarpiece in which collaborates the toledan assembler Juan García de San Pedro. Dated in 1653 and at present located in the parish of Nambroca (Toledo, in which we can appreciate the typical structural and ornamental innovations of the language developed by the artist.

  7. «Ladinia», Sföi cultural dai Ladins dies Dolomites, numm.V. (1981- VIII (1984, Institut Ladin «Micurà de Rü”, San Martin de Tor, Piccolino (Val Badia.

    Directory of Open Access Journals (Sweden)

    Pavao Tekavčić

    1986-12-01

    Full Text Available La rivista «Ladinia», le cui prime quattro annate sono state recensite in «Linguistica» 21 (1981, pp. 325-331, continua ad uscire, conservando il suo profilo, Ia vastità degli argomenti che concernono il mondo ladino ed arricchendosi an­ che di rubriche nuove. Offriamo ai lettori Ia recensione delle annate 1981-1984, concentrandoci anche qui sui contributi linguistici (tanto piu che nei numeri V-VIII, e particolarmente negli ultimi due, i contributi di argomento linguistico occupano più spazio di prima.

  8. Diagnosis of factor VIII deficiency.

    NARCIS (Netherlands)

    Verbruggen, B.; Meijer, P.; Novakova, I.; Heerde, W. Van

    2008-01-01

    The correct diagnosis of factor VIII deficiency and the assessment of severity of the disease are essential for a patient-tailored treatment strategy. An optimal diagnostic procedure comprises sensitive and specific screening methods and factor VIII activity assays. Different screening reagents show

  9. Entrevista/Pedro Gilberto Gomes

    Directory of Open Access Journals (Sweden)

    Demétrio de Azeredo Soster

    2016-12-01

    Full Text Available O professor do Programa de Pós-graduação em Comunicação em Ciências da Comunicação e pró-reitor Acadêmico da Unisinos, Pedro Gilberto Gomes, ao lado de pesquisadores como os professores-doutores Antonio Fausto Neto, Luiz Braga e Jairo Ferreira, é um dos pioneiros nas investigações em torno do fenômeno da midiatização no Brasil e América Latina. Sua pesquisa está fortemente marcada pela percepção de que a humanidade está em meio a uma transformação substancial em seu modo de ser e atuar em decorrência da midiatização, e, com ela, da instauração de uma nova ambiência, “um novo modo de ser no mundo”. Pedro Gilberto Gomes concedeu a seguinte entrevista à Rizoma:

  10. La biblioteca de Pedro Salinas

    Directory of Open Access Journals (Sweden)

    González García, Juana María

    2010-08-01

    Full Text Available Pedro Salinas’ personal library prior to the Spanish Civil War has so far remained almost unknown for both researchers and specialists dealing with his literary works. Preserved by the Cervantes Institute of Secondary School in Madrid, this group of books has however arose great interest. A catalogue of his personal books is contained in this work; this is the result of very slow and accurate classification work and further study of the texts as well as the appropriate thoughts on its history and characteristics.

    La biblioteca personal del poeta Pedro Salinas previa a la Guerra Civil española, ha permanecido prácticamente desconocida hasta el momento para los investigadores y estudiosos de su obra creativa. Conservada entre el fondo documental del Instituto madrileño de Secundaria Cervantes, este conjunto de libros tiene, sin embargo, un gran interés. En este trabajo se publican tanto el catálogo de libros del poeta, resultado de una lenta tarea de clasificación y estudio de los textos así como las convenientes reflexiones en torno a su historia y características.

  11. Pedro José Velarde: un rapsoda callejero en el México del siglo XVIII

    Directory of Open Access Journals (Sweden)

    Bernabéu Albert, Salvador

    2005-12-01

    Full Text Available The Inquisition trial of Pedro José Velarde in 1768 reveals the life and works of this street poet that was very popular in the market of El Baratillo. Velarde was imprisoned because some of his compositions were dedicated to praise the activities of the jesuits, expelled in 1767. He was sentenced to three years in prison serving in the San Juan de Dios Hospital, but died in poverty in 1768.

    Gracias al proceso abierto por la Inquisición mexicana en 1768 podemos reconstruir parcialmente la vida y la obra de Pedro José Velarde, poeta callejero que se hizo famoso en el mercado del Baratillo. Algunas de sus composiciones fueron dedicadas a ensalzar las actividades de los jesuitas, expulsados en 1767, por lo que fue encarcelado y sentenciado a servir durante tres años en el hospital de San Juan de Dios. Murió en 1784 en la pobreza.

  12. Arcos triunfales de San Petersburgo

    OpenAIRE

    Kurz Muñiz, Juan Albert; Gordo, Carmen María

    2001-01-01

    Se conmemora el tricentenario de la ciudad de San Petersburgo, ciudad que nos ha dejado grandiosos monumentos a lo largo de su historia. La importancia de los arcos triunfales, exponentes máximos que reglejan las victorias acaecidas, con un refinamiento y belleza occidental. Erigidos durante los reinados de Pedro I el Grande y Catalina II, monarcas ilustrados que supieron abrir a Rusia hacia la modernidad.

  13. Diagnosis of factor VIII deficiency.

    Science.gov (United States)

    Verbruggen, B; Meijer, P; Novákova, I; Van Heerde, W

    2008-07-01

    The correct diagnosis of factor VIII deficiency and the assessment of severity of the disease are essential for a patient-tailored treatment strategy. An optimal diagnostic procedure comprises sensitive and specific screening methods and factor VIII activity assays. Different screening reagents show variable characteristics and receiver operator characteristic curves are presented showing the relation between sensitivity and specificity of eleven activated partial thromboplastin time reagents. The details of the three methods for factor VIII activity assay, one-stage and two-stage assay and chromogenic assays, are discussed. The chromogenic assay seems to be more sensitive than the one-stage assay with regard to the detection of severe haemophilia. Discrepant results obtained with one-stage and two-stage assays are reviewed and discussed.

  14. Pedro Mourlane Michelena y el pensamiento reaccionario

    Directory of Open Access Journals (Sweden)

    Creus Visiers, Eduardo

    2013-12-01

    Full Text Available Analysis of some central aspects of the work of the Spanish writer Pedro Mourlane Michelena, considered in relation with his fascist ideology and in the context of the summit and decline of the European totalitarianism.Análisis de algunos aspectos centrales de la obra ensayística del escritor español Pedro Mourlane Michelena, considerados en relación con su ideología falangista y en el contexto del auge y declive de los totalitarismos europeos.

  15. Pedro Zamora and Pedro and Me in Requiem: Scoring the Loss

    Directory of Open Access Journals (Sweden)

    A. David Lewis

    2015-09-01

    Full Text Available When originally published at the turn of the century, 'Pedro and Me: Friendship, Loss, and What I Learned' (2000 was riding both the popularity of its reality television roots ''and the growing awareness of homosexuality in the popular consciousness. At that time, too, Macmillan publisher Henry Holt had its own website set up to support Winick’s work; it featured interviews, tour dates, and, most importantly, omitted scenes originally drafted but not completed by the author. The opportunity to finally include this apocrypha was missed in the newer 2009 addition, as the publisher opted for a one-page afterword.  This paper discusses how this constitutes a missed opportunity to reconnect with Pedro. In as much as the original graphic novel—or 'any' graphic novel—is a construction, the tenth anniversary edition of 'Pedro and Me' disallowed the excluded raw material from being included in audience’s score-overdue deconstruction of the work.

  16. Pedro Zamora and Pedro and Me in Requiem: Scoring the Loss

    Directory of Open Access Journals (Sweden)

    A. David Lewis

    2015-09-01

    Full Text Available When originally published at the turn of the century, Pedro and Me: Friendship, Loss, and What I Learned (2000 was riding both the popularity of its reality television roots and the growing awareness of homosexuality in the popular consciousness. At that time, too, Macmillan publisher Henry Holt had its own website set up to support Winick’s work; it featured interviews, tour dates, and, most importantly, omitted scenes originally drafted but not completed by the author. The opportunity to finally include this apocrypha was missed in the newer 2009 addition, as the publisher opted for a one-page afterword.  This paper discusses how this constitutes a missed opportunity to reconnect with Pedro. In as much as the original graphic novel—or any graphic novel—is a construction, the tenth anniversary edition of Pedro and Me disallowed the excluded raw material from being included in audience’s score-overdue deconstruction of the work.

  17. Pedro Salinas y el teatro desde dentro (Pedro Salinas and Theatre from Within

    Directory of Open Access Journals (Sweden)

    Yolanda Benítez Vega

    2013-12-01

    Full Text Available Resumen: Pedro Salinas y el teatro, desde dentro” es el título de este artículo cuya finalidad consiste en realizar un recorrido por la vocación teatral de Pedro Salinas desde sus primeros años hasta el final de sus días: su asistencia a representaciones teatrales, sus contactos con el teatro y sus proyectos como autor dramático tanto los que se realizaron como los que no llegaron a materializarse. El propósito es adentrarnos en el alma teatral del poeta: cómo, cuándo, por qué surge su vocación por el arte escénico, insistiendo en la necesidad de rescatar la faceta de dramaturgo de Pedro Salinas como una constante más en la labor del poeta, profesor y crítico.Abstract: "Pedro Salinas and the theatre, from inside " it is the title of this article which purpose consists of realizing a tour for Pedro Salinas's theatrical vocation from his first years until the end of his days: his assistance to theatrical representations, his contacts with the theatre and his projects like dramatic author so much those who were realized as those who did not manage to materialize. The intention is to enter the theatrical soul of the poet: how, when, why his vocation arises for the scenic art, insisting on the need to rescue the playwright's facet of Pedro Salinas as one more constant in the labor of the poet, teacher and critic.

  18. Pedro Ferreira, um escultor baiano desconhecido Pedro Ferreira, an unknown sculptor from Bahia

    Directory of Open Access Journals (Sweden)

    Maria Helena Ochi Flexor

    2008-12-01

    Full Text Available Este trabalho é o resultado do início de um estudo sobre o escultor Pedro Ferreira. Embora seja autor de obras importantes, passa quase desapercebido na historiografia da arte baiana. Trata-se de artista que pertence ao tempo em que o neoclassicismo se impunha à cultura Ocidental, porém, ainda restavam, na Bahia, as práticas do período barroco, em especial a cópia dos grandes mestres renascentistas. Pedro Ferreira foi um desses artistas e teve como principal inspirador Murillo, da escola espanhola.This work is the result of a beginning study about a sculptor Pedro Ferreira. Although he was author of important workmanships, he passes almost unknown in the bahian history of art. He was an artist who lives belongs a time when the neoclassicismo was imposed to the Occidental culture, but, still remained in Bahia, the practical ones of the baroque period, in special the copy of the great Renaissance masters. Pedro Ferreira was one of these artists and has inspired, as main artist, Murillo, of the Spanish school.

  19. Pedro de mena, escultor (1628-1688)

    OpenAIRE

    López, María del Pilar

    2014-01-01

    Este nuevo libro de Lázaro Gila, profesor del Departamento deHistoria del Arte de la Universidad de Granada, presenta un cuidadosoexamen de las esculturas que a lo largo de su vida realizó el artistagranadino Pedro de Mena y Medrano.Se compone de una presentación historiográfica del trabajo delartista, de la exposición de su reconocimiento dentro del desarrollodel arte en las ciudades de Granada y Málaga —en las que vivió ytrabajó—, de lo que el autor llama su “perfil biográfico” y, por últim...

  20. Stark broadening parameter tables for Ar VIII

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.

    1999-01-01

    Full Text Available Using a semiclassical approach, we have calculated electron−, proton−, and He III−impact line widths and shifts for 9 Ar VIII transitions as a function of temperature and perturber density.

  1. Stark broadening parameter tables for Kr VIII

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.

    1999-01-01

    Full Text Available Using a semiclassical approach, we have calculated electron−, proton−, and He III−impact line widths and shifts for 6 Kr VIII multiplets as a function of temperature and perturber density.

  2. Impact of Flooding on Fishermen's families in Pedro Community ...

    African Journals Online (AJOL)

    Climatic change impact is envisaged to lead to increase in the frequency of occurrence of floods. This study examined the effect of flooding on fishermen's families in Pedro village, Iwaya, Lagos. A total of 50 fishermen living in Pedro Community, Iwaya-Lagos, Nigeria were interviewed using structured questionnaires that ...

  3. Pedro Teixeira y su viaje por Mesopotamia

    Directory of Open Access Journals (Sweden)

    Fuente del Pilar, José Javier

    2005-04-01

    Full Text Available Pedro Teixeira es un integrante notable de la ilustre nómina de los viajeros portugueses que, a finales del s, XVI y principios del XVII, ensancharon para Occidente las fronteras del mundo. Su conocimiento en España se debe a la publicación en 1994 de su obra «Relaciones del Origen, Descendencia y Sucesión de los Reyes de Persia, y de Harmuz, y de un viaje hecho por el autor dende la India hasta Italia por tierra», en edición realizada por el profesor Eduardo Barajas Sala, lamentablemente fallecido en 1997. En este artículo se ofrece una reseña biográfica de Pedro Teixeira, y un análisis del viaje narrado por el autor en la última parte de sus «Relaciones »: el que desde Ormuz le conducirá, a través de Mesopotamia, hasta la costa del Mediterráneo.…

  4. El amante inaudito: duelo, melancolía y amor intransitivo en el personaje Pedro Páramo

    Directory of Open Access Journals (Sweden)

    Alfredo Rosas Martínez

    2016-07-01

    Full Text Available El propósito de este artículo consiste en analizar las características del duelo, la melancolía y el amor en el personaje Pedro Páramo. La muerte de su esposa, Susana San Juan, le provoca un estado de duelo. Posteriormente, el humor melancólico lo conduce a un estado de tristeza y de profunda decadencia vital. No obstante, hay un aspecto que lo reivindica: el amor. En este sentido, es fundamental la influencia de Rainer Maria Rilke a propósito del amor intransitivo (jamás correspondido. La melancolía convierte en poeta a Pedro Páramo. La bilis negra del humor melancólico le sirve como tinta oscura para dar cuenta de su amor sin respuesta, y se convierte así en un amante inaudito.

  5. Pedro Salinas: la letra y la persona

    Directory of Open Access Journals (Sweden)

    Escartín Gual, Montserrat

    2002-12-01

    Full Text Available This article is a Pedro Salinas's homage in the fifty anniversary of his death. Here, we analise his attitude in front of life and his securities through his poems, personal letters and essais. The poet criticizes the materialistic american stil of life, where he should live during his exile until his death (1936-1951. Against the hurry, the profitable things, the technology, the money..., Salinas believes in his language, slowness, friendship, contemplation of countryside, art, spiritualism, optimism, etc. Son of the Institución Libre de Enseñanza's ideas, his personal ethics looked for the biggest perfection trought the will.Este artículo es un homenaje a Pedro Salinas al cumplirse el cincuentenario de su muerte. En él, se analiza su actitud ante la vida y sus valores a través de sus poesías, cartas personales y ensayos. El poeta critica el materialismo del modelo americano en el que se vio obligado a vivir desde que se exilió hasta su muerte (1936-1951. Frente a la prisa, lo rentable, la tecnología, el dinero...; Salinas cree en su idioma, la lentitud, la amistad, la contemplación del paisaje, el arte, lo espiritual, el optimismo, etc. Hijo de las ideas de la Institución Libre de Enseñanza, su ética personal buscó la mayor perfección a través de la voluntad.

  6. En el 416 aniversario de la fundación de Pamplona: Don Pedro de Orsua: el caballero de Eldorado

    Directory of Open Access Journals (Sweden)

    Santiago Pérez

    1965-11-01

    Full Text Available Fue el capitán Pedro de Orsua, ongmario de un antiquísimo poblado, que hoy por evolucion del vocablo se llama Ujué y que anteriormente se llamó Ursua, palabra que en Eúscaro quiere decir paloma. Dice la leyenda que en el siglo VIII, cuando las huestes árabes se habían desparramado por España y pugnaban por irrumpir en Francia, en un lugarejo del valle del Orba, en el partido de Olite, que pertenecía a la quinta merindad del reino de Navarra, había una cueva casi inaccesible en torno de la cual revoloteaba una paloma y que un zagal trepó entre las breñas y descubrió una imagen de la virgen, la que en razón de su alada compañera se llamó de Ursua.

  7. Physicochemical characterisation of rVIII-SingleChain, a novel recombinant single-chain factor VIII.

    Science.gov (United States)

    Schmidbauer, Stefan; Witzel, Reinhild; Robbel, Lars; Sebastian, Petra; Grammel, Nicolas; Metzner, Hubert J; Schulte, Stefan

    2015-08-01

    rVIII-SingleChain is a novel recombinant single-chain factor VIII (FVIII) construct, comprising covalently bonded heavy and light chains. Post-translational modifications of FVIII affect physicochemical parameters, including hydrophobicity and charge. The most relevant post-translational modifications of FVIII products are N-glycosylation of asparagine residues and tyrosine sulphations. Here, the physicochemical properties, thrombin cleavage products and post-translational modifications of rVIII-SingleChain were investigated and compared against commercially available recombinant FVIII (rFVIII) products with a predominant two-chain structure (B-domain deleted rFVIII and full-length rFVIII). rVIII-SingleChain was expressed in Chinese hamster ovary (CHO) cells and purified by chromatographic methods. Physicochemical properties of rVIII-SingleChain or thrombin-derived cleavage products were assessed using size-exclusion chromatography, reversed-phase chromatography and sodium dodecyl sulphate polyacrylamide gel electrophoresis. Analysis of the respective carbohydrate structures was performed after release of N-glycans by PNGase F followed by fluorescence labelling and high-performance liquid chromatography. Proteolysis by trypsin generated the corresponding peptides, which were analysed for sulphated tyrosines by liquid chromatography-electrospray ionisation time of flight-mass spectrometry. rVIII-SingleChain was shown to be of high purity and homogeneity, and presented a well-defined single-chain molecule with predominant β-sheet conformation. The coagulation-relevant thrombin-activation products of rVIII-SingleChain were comparable with those obtained by activation of commercially available rFVIII products. rVIII-SingleChain post-translational modifications were similar to other CHO cell-derived rFVIII products for N-glycopattern and tyrosine sulphation. In conclusion, rVIII-SingleChain is of high homogeneity and purity, and provides an expected cleavage pattern on

  8. Pedro Meyer vastutab oma piltide eest / Laura Kuusk

    Index Scriptorium Estoniae

    Kuusk, Laura, 1982-

    2007-01-01

    Mehhiko fotograafi Pedro Meyeri tutvustus. P. Meyeri ettekande tekst "Kui dokumentaalne teile meeldis, siis digitaalset hakkate armastama", esitatud Soomes Jyväskyläs 2006. a. oktoobris toimunud fotograafiakonverentsil

  9. Blood coagulation factor VIII: An overview

    Indian Academy of Sciences (India)

    Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the ...

  10. Pedro Lemebel: género y sociedad Pedro Lemebel: Gender and Society

    OpenAIRE

    Leonidas Morales T

    2009-01-01

    El artículo, primero, examina la crónica urbana de Pedro Lemebel a la luz de sus condiciones históricas de producción y de lectura (la memoria de la dictadura y el presente de la mercancía globalizada). Luego, ofrece un análisis de algunas formas de su discurso (que afectan tanto al género sexual como a los recursos retóricos) y del modo en que este discurso, como discurso crítico, piensa críticamente la vida cotidiana chilena.The following article, first, examines the urban chronicle of Pedr...

  11. Don Pedro Laín Entralgo

    Directory of Open Access Journals (Sweden)

    Roberto Serpa Florez

    2001-08-01

    Full Text Available

    Al amanecer del martes 5 de junio murió don Pedro Laín Entralgo eminente médico, escritor, historiador de la medicina y académico, uno de las más grandes pensadores y humanistas españoles del siglo veinte (1908-2001. En España el trato de “don” es el de más alta categoría que puede darse: don Gregorio Marañón, don José Ortega y Gasset, don Miguel de Unamuno, don Carlos Jiménez Díaz, don Antonio Machado.

    Don Pedro Laín Entralgo fue uno de los más grandes historiadores de la medicina en todo el mundo:

    Miembro de la Real Academia de Medicina Española (desde 1948, Miembro de la Real Academia Española de la Lengua (desde 1954, Miembro de la Real Academia Española de Historia (desde 1962; por muchos años fue Presidente de la Real Academia de la Lengua y miembro numerario de la Academia de Medicina.

    Catedrático de Historia de la Medicina de la Universidad Central y Rector de ella hasta 1956, don Pedro Laín Entralgo dirigió y editó el más completo e importante tratado de Historia de la Medicina.

    En los siete volúmenes de La Historia Universal de la Medicina, publicados entre los años 1972 y 1975, colaboraron más de un centenar de autores de veinte países. Otros libros de los muchos que escribió:

    “España como problema” (1949, su manual de “Historia de la Medicina” (1978, “Historia de la Medicina Moderna y Contemporánea” (1963, “La relación médico-enfermo, historia y teoría” (1961, El que hacer del médico a lo largo de la historia de la cultura (el ars medica de los romanos, la thekné de los griegos y la técnica deshumanizada del siglo XX, la relación humana entre el médico y su paciente, las relaciones entre la praxis (el conocimiento y las destrezas y la ética y los valores, fueron objeto de sus meditaciones filosóficas.

    En el Epílogo de su libro La Medicina actual (1973 don Pedro Laín Entralgo escribió:

    “La fabulosa medicina actual es, en

  12. Une version franco-canadienne de la Physiotherapy Evidence Database (PEDro) Scale : L'Échelle PEDro

    Science.gov (United States)

    Laroche, Chantal; Sutton, Anne; Guitard, Paulette; King, Judy; Poitras, Stéphane; Casimiro, Lynn; Tremblay, Manon; Cardinal, Dominique; Cavallo, Sabrina; Laferrière, Lucie; Grisé, Isabelle; Marshall, Lisa; Smith, Jacky R.; Lagacé, Josée; Pharand, Denyse; Galipeau, Roseline; Toupin-April, Karine; Loew, Laurianne; Demers, Catrine; Sauvé-Schenk, Katrine; Paquet, Nicole; Savard, Jacinthe; Tourigny, Jocelyne; Vaillancourt, Véronique

    2015-01-01

    RÉSUMÉ But : Effectuer une traduction franco-canadienne de la PEDro scale sous l'appellation proposée d'Échelle PEDro et examiner la validité de son contenu. Méthodologie : Nous avons utilisé une approche modifiée de la méthodologie de validation transculturelle de Vallerand. Une traduction renversée parallèle de la PEDro scale a d'abord été effectuée à la fois par des traductrices professionnelles et des chercheurs cliniciens. Ensuite, un premier comité d'experts (P1) a examiné les versions traduites et a créé la première version expérimentale de l'Échelle PEDro. Cette version a été évaluée par un deuxième comité d'experts (P2). Finalement, 32 chercheurs cliniques ont évalué cette deuxième version expérimentale de l'Échelle PEDro à l'aide d'une échelle de clarté (étendue de 5 points) et ont proposé les modifications finales. Résultats : Pour les différents énoncés de la version finale de l'Échelle PEDro, les moyennes sur l'échelle de clarté montrent un niveau élevé puisqu'elles varient entre 4,0 et 4,7 sur un score maximal de 5 points. Conclusion : Les quatre étapes rigoureuses du processus ont permis de produire une version franco-canadienne valide de l'Échelle PEDro. PMID:26839449

  13. ["El Informe Médico-Moral de la Penosissima y Rigorosa Enfermedad de la Epilepsi" (1763) by the Spaniard Pedro de Horta, the 1st American treatise on epilepsy].

    Science.gov (United States)

    García-Albea, E

    1998-06-01

    In 1763 Pedro de Horta was requested by the prioress of the convent of San Gerónimo in Puebla de los Angeles to draw up a report to establish whether the epidemic of queer turns, violent shaking or epilepsy which affected the novices was caused by the Devil or was due to natural causes. Pedro de Horta, a doctor qualified in Mexico, methodically and thoroughly prepared an extensive monographic treatise on the illness which included all that was known at the time. The report showed the fierce debates provoked by the subject of epilepsy in the eighteenth century regarding whether it was of natural or supernatural origin. It also contained detailed accounts of the episodes, their causes and treatment. The Spaniard Pedro de Horta should be justly recognized as the first American epileptologist.

  14. Heat transfer burnout of Mark VIII fuel

    Energy Technology Data Exchange (ETDEWEB)

    Bernath, L.

    1956-08-01

    The operating conditions to which the special Mark VIII quatrefoils will be exposed during the proposed piloting program have been compared with the conditions required to cause burnout, using an established method of calculating these conditions. The results of this comparison permit the following conclusions to be drawn: (1) With normal flow of coolant through the special elements the heat flux to be encountered in the R-8 cycle (1400 MW) will be 70% or that required to cause burnout (30% margin from burnout). (2) With a reduction of coolant flow to 82% of normal through one tube of a special element, burnout of that fuel column is possible in the R-8 cycle. (3) In the R-6 cycle (1280 MW), the margin from burnout in the special Mark VIII quatrefoils is 42% with full flow and 20% with the above reduced coolant flow. A similar comparison of operating conditions predicted for the L-3 cycle (full Mark VIII charge) shows that, even at the highest power level (1250 MW), the margin from burnout is greater than 55% with normal flow and 40% with reduced flow.

  15. Sediment-quality and water-toxicity data from 10 sites on the Westside Creeks and San Antonio River, San Antonio, Texas, 2014

    Science.gov (United States)

    Crow, Cassi L.; Wilson, Jennifer T.; Kunz, James L.

    2016-01-01

    Sediment samples and samples for water-toxicity testing were collected during 2014 from several streams in San Antonio, Texas known locally as the Westside creeks (Alazán, Apache, Martínez, and San Pedro Creeks) and from the San Antonio River. Samples were collected once during base-flow and again after periods of storm-water runoff (post-storm conditions) to determine baseline sediment- and water-quality conditions. Streambed-sediment samples were analyzed for selected constituents, including trace elements and organic contaminants such as pesticides, polychlorinated biphenyls (PCBs), brominated flame retardants, and polycyclic aromatic hydrocarbons (PAHs).

  16. San Francisco District Laboratory (SAN)

    Data.gov (United States)

    Federal Laboratory Consortium — Program CapabilitiesFood Analysis SAN-DO Laboratory has an expert in elemental analysis who frequently performs field inspections of materials. A recently acquired...

  17. A interação existencial entre seres humanos e animais no romance Pedro Páramo, de Juan Rulfo = The existential interaction between human beings and animals in the novel Pedro Páramo by Juan Rulfo

    Directory of Open Access Journals (Sweden)

    Evely Vânia Libanori

    2013-01-01

    Full Text Available Em Pedro Páramo, de Juan Rulfo, o corvo, o cavalo e o gato são animais que mantêm estreita ligação existencial com o ser humano. A interação ser humano-animal é fundamental para o entendimento de temas filosóficos presentes no romance, como a identidade humana, o outro, a morte. O corvo é o batedor da chegada de Juan Preciado no mundo da morte. O cavalo de Miguel Páramo é o único ser que sofre, verdadeiramente, a morte do seu tutor. O gato é o animal que faz visitas noturnas a Susana San Juan, com quem estabelece um diálogo somente inteligível para os dois. A integração entre personagens humanas e animais em Pedro Páramo mostra a comunicação entre seres pertencentes a diferentes espécies animais. No romance, seres humanos, corvos, cavalos e gatos têm mais semelhanças entre si do que a cultura ocidental antropocêntrica conhece.In Pedro Páramo by Juan Rulfo, the raven, the horse and the cat are animals that maintain a close existential link to the human beings. In the book, this human being/animal interaction is fundamental to the understanding of philosophical themes such as the identity, the other, and the death. In the story, the raven is the escort of Juan Preciado arrival into the death world. Miguel Páramos’s horse is the only being that genuinely suffers because of the death of its guardian, that is, Miguel’s death. The cat is the animal that make night visits to Susana San Juan to whom it speaks in a way that is understood by the two of them only. The connection between human and animal characters in Pedro Páramo shows the communication among beings that belong to different animal species. In the novel, human beings, ravens, horses, and cats are much more alike than the western anthropocentric culture has it.

  18. On Persons and Immortality Symposium on Pedro Tabensky ...

    African Journals Online (AJOL)

    On Persons and Immortality Symposium on Pedro Tabensky, Happiness: Personhood, Community, Purpose. ... Concentrating on the example of immortality, I argue that, while there are undoubtedly disadvantages associated with the immortal life, these are contingent rather than essential to the notion of being a person.

  19. Preparing for ENDF/B-VIII

    Science.gov (United States)

    Brown, David

    2017-09-01

    Although the next major release of the ENDF/B library is not due until the 2017-2018 time frame, ENDF/B-VIII is already positioned to become the most important release of the library in some time. ENDF/B-VIII will be built around the Neutron Reaction Standards as well as the 1H, 16O, 56Fe, 235U, 238U and 239Pu evaluations developed as part of the Coordinated International Evaluation Library Organization (CIELO) pilot project. In this contribution, we summarize these improvements as well as the many other improvements to ENDF that have already been made or are scheduled to be made in the next year. Improvements already included in the ENDF/B-VIII beta releases: • Aggressive use of the flexible and physically correct LRF=7 resolved resonance format in 12 updated evaluations (35,37Cl, 40Ca, 54,56,57Fe, 63,65Cu and 182,183,184,186W) • Thermal capture gammas from the EGAF project (6,7Li, 11B, 19F, 23Na, 27Al, 28Si, 35,37Cl) • Thermal Scattering Law evaluations from NCSU (α and β phase SiO2, SiC, lucite, BeO, and polyethylene) and from the CAB-CNL collaboration (heavy and light water) • Many new evaluations in the neutron sublibrary (n, 12,13C, 40Ar, 54,57,58Fe, 58,59,60,61,62,64Ni, 63,65Cu, 73As, 120Sn, 236m1Np) Inclusion of Red Cullen's EPICS2014 library, updating the photo-atomic, electron and atomic-relaxation sublibraries. Many improvements are planned in the next year including new evaluations such as charged particle evaluations translated from LLNL's ECPL. In addition to these major changes, ENDF/B-VIII will be the first official library released simultaneously in the legacy ENDF-6 and the newly developed Generalized Nuclear Data (GND) formats.

  20. San Marino.

    Science.gov (United States)

    1985-02-01

    San Marino, an independent republic located in north central Italy, in 1983 had a population of 22,206 growing at an annual rate of .9%. The literacy rate is 97% and the infant mortality rate is 9.6/1000. The terrain is mountainous and the climate is moderate. According to local tradition, San Marino was founded by a Christian stonecutter in the 4th century A.D. as a refuge against religious persecution. Its recorded history began in the 9th century, and it has survived assaults on its independence by the papacy, the Malatesta lords of Rimini, Cesare Borgia, Napoleon, and Mussolini. An 1862 treaty with the newly formed Kingdom of Italy has been periodically renewed and amended. The present government is an alliance between the socialists and communists. San Marino has had its own statutes and governmental institutions since the 11th century. Legislative authority at present is vested in a 60-member unicameral parliament. Executive authority is exercised by the 11-member Congress of State, the members of which head the various administrative departments of the goverment. The posts are divided among the parties which form the coalition government. Judicial authority is partly exercised by Italian magistrates in civil and criminal cases. San Marino's policies are tied to Italy's and political organizations and labor unions active in Italy are also active in San Marino. Since World War II, there has been intense rivalry between 2 political coalitions, the Popular Alliance composed of the Christian Democratic Party and the Independent Social Democratic Party, and the Liberty Committee, coalition of the Communist Party and the Socialist Party. San Marino's gross domestic product was $137 million and its per capita income was $6290 in 1980. The principal economic activities are farming and livestock raising, along with some light manufacturing. Foreign transactions are dominated by tourism. The government derives most of its revenue from the sale of postage stamps to

  1. Acquired Factor VIII Inhibitors: Three Cases

    Directory of Open Access Journals (Sweden)

    Tay Za Kyaw

    2013-03-01

    Full Text Available Acquired hemophilia A is a rare, but devastating bleeding disorder caused by spontaneous development of autoantibodies directed against coagulation factor VIII. In 40%-50% of patients it is associated with such conditions as the postpartum period, malignancy, use of medications, and autoimmune diseases; however, its cause is unknown in most cases. Acquired hemophilia A should be suspected in patients that present with a coagulation abnormality, and a negative personal and family history of bleeding. Herein we report 3 patients with acquired hemophilia A that had different underlying pathologies, clinical presentations, and therapeutic responses. Factor VIII inhibitor formation in case 1 occurred 6 months after giving birth; underlying disorders were not identified in cases 2 or 3. The bleeding phenotype in these patients’ ranged from no bleeding tendency with isolated prolongation of APTT (activated partial thromboplastin time to severe intramuscular hematoma and hemarthrosis necessitating recombinant activated factor VII infusion and blood components transfusion. Variable responses to immunosuppressive treatment were also observed.

  2. 12 CFR 611.1137 - Title VIII service corporations.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Title VIII service corporations. 611.1137 Section 611.1137 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ORGANIZATION Service... authorities granted under title VIII of the Act to act as an agricultural mortgage marketing facility. (b) How...

  3. The influence of prophylactic factor VIII in severe hemophilia A

    Science.gov (United States)

    Gissel, Matthew; Whelihan, Matthew F; Ferris, Lauren A; Mann, Kenneth G; Rivard, Georges E; Brummel-Ziedins, Kathleen E

    2013-01-01

    Introduction Hemophilia A individuals displaying a similar genetic defect have heterogeneous clinical phenotypes. Aim To evaluate the underlying effect of exogenous factor (f)VIII on tissue factor (Tf)-initiated blood coagulation in severe hemophilia utilizing both empirical and computational models. Methods We investigated twenty-five clinically severe hemophilia A patients. All individuals were on fVIII prophylaxis and had not received fVIII from 0.25 to 4 days prior to phlebotomy. Coagulation was initiated by the addition of Tf to contact-pathway inhibited whole blood ± an anti-fVIII antibody. Aliquots were quenched over 20 min and analyzed for thrombin generation and fibrin formation. Coagulation factor levels were obtained and used to computationally predict thrombin generation with fVIII set to either zero or its value at the time of the draw. Results Due to prophylactic fVIII, at the time of the blood draw, the individuals had fVIII levels that ranged from hemophilia A. The combination of each individual's coagulation factors (outside of fVIII) determine each individual's baseline thrombin potential and may affect bleeding risk. PMID:21899664

  4. Pedro Muguruza Otaño (1893-1952): Aproximación histórica a su obra arquitectónica

    OpenAIRE

    Bustos Juez, Carlota

    2015-01-01

    El arquitecto Pedro Muguruza (1893-1952) fue protagonista de la cultura arquitectónica española de la primera mitad del siglo XX. El estudio de su obra ha sido una carencia dentro de la historiografía de la materia, por lo que la tesis constituye una primera investigación en conjunto de su trayectoria profesional. Muguruza realizó una obra abundante y diversa, pero además fue catedrático de la Escuela de Arquitectura de Madrid, académico de San Fernando y primer director general de arquitectu...

  5. Comportamiento de las plántulas de rosas (Rosa sp.). Injertadas en las diferentes fases de la luna: Pedro Moncayo - Ecuador 2014

    OpenAIRE

    Vinueza Vinueza, Marco Vinicio

    2015-01-01

    This research was developed in the Rancho San Jorge farm, located in Santa Clara neighborhood, Tupigachi parish, Canton Pedro Moncayo. It was evaluate the behavior of the rose baby plants (Rosa sp.) grafted at different phases of the moon. It was used as rootstocks, the rose known as Natal Briar and the commercial variety Cherry-O! ® was grafted . Four were the treatments evaluated: T1 (grafts in First Quarter), T2 (grafts in Full Moon), T3 (grafts in Third Quarter) and T4 (grafts in ne...

  6. Pedro Paulet: Peruvian Pioneer of the Space Age

    OpenAIRE

    Canales Romero, Martin Juan

    2010-01-01

    1969 was the year when man stepped on the Moon. Many space pioneers have contributed to carry out the major endeavor achieved by humankind. Pedro Paulet (July 2, 1874 in Arequipa, Peru – 1945 in Buenos Aires, Argentina) was a Peruvian scientist who in 1895 conducted experiments on a rocket motor made of vanadium steel that burned a combination of nitrogen peroxide and gasoline. There are indications that actually Paulet had invented the rocket engine in the Sorbonne University, France, where ...

  7. Environmental Impact Analysis Process. Environmental Assessment for Space Division Proposed Housing, White Point, San Pedro, California

    Science.gov (United States)

    1984-07-01

    bedrock is generally white, gray and brown with orange brown staining on F-23 Convem Consunlan. in. 6 weathered surfaces, moist, soft to hard, slightly to...old building site is marked by a row of olive trees (Olea europea) atid scatter.-d tros of BraziiLari pepper tret:i ( Schinus terebinthifolius

  8. A 25-YEAR HISTORY OF LAND COVER CHANGE IN THE SAN PEDRO RIVER

    Science.gov (United States)

    Vegetation change in the American West has been a subject of concern throughout the twentieth century. Although many of the changes have been recorded qualitatively through the use of comparative photography and historical reports, little quantitative information has been ava...

  9. THE CHANGING WATERSHED: A 25-YEAR HISTORY OF LAND COVER CHANGE IN THE SAN PEDRO RIVER

    Science.gov (United States)

    Vegetation change in the American West has been a subject of concern throughout this century. Although many of the changes have been recorded qualitatively through the use of comparative photography and historical reports, little quantitative information has been available on the...

  10. Anthropocentric use of plant in the homegarden San Pedro Ixtlahuaca, Oaxaca, México

    Directory of Open Access Journals (Sweden)

    Jesús Hernández Ruiz

    2013-01-01

    Full Text Available Using providing farm families plant agrobiodiversity found in the homegarden can understand how communities perceive, interpret and know the environment around them, the most illustrative approach is to generate plant elements anthropocentric categories of use defined as those where a group of people gives a utility value to the species, therefore, the objective of this research was to describe using traditional anthropocentric and families express and agrobiodiversity of plants in their homegarden, to determine use is anthropocentric applied semi-structured questionnaires with openquestions, tours and interviews, the information gathered was presented to the participating households in order to supplement such information. The results recorded were 67 species belonging to 50 genera and 37 families which are categorized into nine anthropocentric uses: medicinal in people, animal medicine, food or groceries, ornamentals, spices, or religious rituals, structural, for product development, used as firewood and to provide shade, these results show that the composition of the solar plant is based on the needs and decisions of the family unit.

  11. Agua, faenas y organización comunal: San Pedro de Casta - Huarochirí

    Directory of Open Access Journals (Sweden)

    Paul H. Gelles

    1984-12-01

    Full Text Available El rol importante que ha desempeñado el manejo del agua en laorganización social y en la formacibn de las llamadas "sociedades hidraúlicas" es un tema que ha interesado a muchos cienfistas sociales. El siguiente artículo, que tiene como enfoque al trabajo comunal, demuestra la importancia del agua en la organización social de una comunidad campesina andina. El autor es alumno del Post-Grado de Antropología en la Pontificia Universidad Católica. Este articulo forma parte de una tesis elaborada en el Post-Grado de la Pontificia Universidad Católica.

  12. Environmental Impact Analysis Process. Environmental Assessment Proposed SMC Military Family Housing, San Pedro, California

    Science.gov (United States)

    1998-12-01

    Ficus benjamina Ficus carica Ficus elastica Ficus macrophylla Ficus microcarpa Ficus rubiginosa Morus alba...Broussonetia papyrifera Ficus benjamina Ficus carica Ficus elastica Ficus microcarpa Ficus rubiginosa Morus alba paper mulberry weeping...BUXACEAE Buxus microphylla var. japonica Japanese boxwood CACTACEAE Opuntia ficus -indica Indian-fig CAMPANULACEAE Campanula spp.

  13. Population status of prairie dogs (Cynomys ludovicianus) in the San Pedro River Basin, Sonora

    Science.gov (United States)

    Efren Moreno-Arzate; Carlos A. Lopez Gonzalez; Gerardo Carreon Arroyo

    2013-01-01

    The black tailed prairie dog (Cynomys ludovicianus) is a species of conservation concern for Mexico, the United States and Canada. Populations in Mexico (including those in Sonora), which are considered endangered by the Mexican authority, require additional conservation efforts to maintain them on the long term. Our objective was to determine population size and...

  14. Petroleum system of the Barua and Motatan fields and the San Pedro-Machango area

    Energy Technology Data Exchange (ETDEWEB)

    Navarro, A.; Diaz, F.; Rodriguez, I. [S.A., Maraven (Venezuela)

    1996-08-01

    The study area is located in the Costa Bolivar (onshore) in the Maracaibo Basin, being framed by Ceuta (offshore) and Tomoporo fields to its west and the Valera fault zone to the east, Mene Grande field to the north and La Ceiba to the south. Eocene oil accumulations are the most important for the study area. Probably this oil was generated and migrated during Miocene-Holocene time. Heavy oil accumulations occur in Miocene intervals, although they have not been considered commercial. It is possible that this oil was generated during early to late Eocene and suffered later biodegradation and remigration. Structurally, it is characterized by different and highly complex tectonic events. Normal faulting occurred during Cretaceous and Eocene times. During the latter, periods of inversion were present that created structural highs where oil generated from La Luna Formation (Cretaceous) accumulated. Major structural deformation occurred during upper Eocene and lower Miocene (Andes uplift). This deformation shows an increase from west (Barua) to east where the Valera fault zone is present. The study area shows a regional dip towards the south, while during the Eocene it dipped towards the north, due to the foredeep condition of the area, when up to 15,000 ft of sediments were deposited, based on seismic data. Porosities vary from 8% to 18% within the area. Fractures are present and they enhance oil production.

  15. MÁS QUE UNA SUMA DE CASAS: LA UNIDAD VECINAL VILLA SAN PEDRO DE CORONEL

    Directory of Open Access Journals (Sweden)

    Stéphane Franck Demiddel

    2009-01-01

    Full Text Available Con el desarrollo industrial de la provincia, parcialmente promovido por la Corporación de Fomento, CORFO, desde el terremoto de 1939, y la construcción de la planta CAP-Huachipato en 1950, la CORVI buscó construir un conjunto para satisfacer la creciente necesidad habitacional. El terremoto de 1960 incorporó, indudablemente, una extrema urgencia al encargo. Por el particular entorno geográfico de la ciudad de Concepción, la institución se enfrentó a la escasez de terrenos baratos cercanos a Concepción, por lo que consideró un área perteneciente a la comuna de Coronel, pero, por su ubicación e importancia, era considerada como parte integrante de Concepción. Otro aspecto relevante es el fundamento o discurso político que incorporaba la Unidad Vecinal, seguramente fomentado por el terremoto político causado por la revolución cubana de 1959 y el remezón que produjo en la política de EE.UU. frente a los países latinoamericanos. Los arquitectos Raúl Farrú y Enrique Porte se encargaron del diseño de este particular proyecto habitacional que ofrecía 1.918 alojamientos, repartidos entre viviendas unifamiliares y departamentos. Con este proyecto, sea por el diseño arquitectónico y urbano, o por la política de selección de usuarios, la CORVI implementó una forma de crear una nueva ciudad, el paso inicial de un proyecto mayor. La permanencia, o sobrevivencia, de algunos servicios, como los colegios y algunos comercios, demostraron el logro y éxito de la propuesta de la CORVI, que iba mucho mas allá del diseño físico ya que incorporaba otra variante bastante más compleja como el uso o la función. Esta diversidad de funciones y actividades, en conjunto con la oferta habitacional, convirtieron, finalmente, este proyecto en una ciudad satélite prácticamente autónoma.

  16. The achkay, the cacique and the neighbour: oral tradition and talk in San Pedro de Pariarca

    Directory of Open Access Journals (Sweden)

    1986-01-01

    Full Text Available L'auteur traite plusieurs versions de la tradition orale andine concernant l'Achkay (personnage mythique anthropophage, recueillies dans une communauté Quechua de la cordillère centrale du Pérou. Elle établit des liens entre cette tradition et d'autres aspects de l'histoire mythique de la communauté étudiée. Tout particulièrement, l'intérêt est porté sur la fonction socio-symbolique de l'image de l'Achkay en tant que mode d'expression des notions de la marginalité et de l'asociabilité. Ce symbole opère à plusieurs niveaux du langage, aussi bien dans les récits traditionnels que dans le discours quotidien de la conversation. La autora discute diversas versiones de aquella tradición andina que trata de la Achkay (personaje mítico antropófago, recogidas en una comunidad Quechua situada en la cordillera central del Perú. Se establece una conexión entre ésta y otras tradiciones pertenecientes a la historia mítica de esta comunidad. El artículo se centra en la función social y simbólica que juega tal personaje, como vehículo para expresar determinadas nociones sobre la marginalidad y la asociabilidad. Este símbolo es manejado en diversos niveles del lenguaje, tanto en los relatos tradicionales como en el discurso conversacional de cada día. The author discusses versions of the Andean oral tradition regarding the Achkay (an anthropophagous mythic ancestress, collected in a Quechua community situated in Central highland Peru. She establishes a relationship between this tradition and traditions dealing with other aspects of the community's mythic history. The article concentrates on the social and symbolic function of Achkay as a means of expressing culturally specific notions of marginality and associability. The symbol is wielded at various levels of language, as much in narratives as in everyday conversational discourse.

  17. Environmental Assessment for Slope Stabilization Projects at Fort MacArthur, San Pedro, California

    Science.gov (United States)

    2012-01-01

    Scientific Name) Common Name (Scientific Name) Black-footed Albatross (Pheobastria nigripes) Spotted Owl (occidentalis ssp.) Black Turnstone (Arenaria...Marine Aquarium, located just south of the wetland. The wetland is a known feeding habitat of the California Least Tern (USAF 2009b), which is not a

  18. San Pedro meeting on Wide Field Variability Surveys: Some concluding comments

    Directory of Open Access Journals (Sweden)

    Feast Michael W.

    2017-01-01

    Full Text Available This is a written version of the closing talk at the 22nd Los Alamos Stellar pulsation conference on wide field variability surveys. It comments on some of the issues which arise from the meeting. These include the need for attention to photometric standardization (especially in the infrared and the somewhat controversial problem of statistical bias in the use of parallaxes (and other methods of distance determination. Some major advances in the use of pulsating variables to study Galactic structure are mentioned. The paper includes a clarification of apparently conflicting results from classical Cepheids and RR Lyrae stars in the inner Galaxy and bulge. The importance of understanding non-periodic phenomena in variable stars, particularly asymptotic giant branch variables and R Coronae Borealis stars, is stressed, especially for its relevance to mass-loss in which pulsation may only play a minor role.

  19. A arquitectura das Termas romanas de S. Pedro do Sul

    Directory of Open Access Journals (Sweden)

    Helena Frade

    1992-01-01

    Full Text Available Comenzamos el trabajo con una introducción general en la que se pone de manifiesto la escasez de estudios sobre el termalismo antiguo en Portugal y la mala conservación de la mayoría de los restos conocidos. Pasamos, a continuación, a tratar del balneario de Sao Pedro do Sul, localizado en la feligresía de Várzea, ayuntamiento de Sao Pedro do Sul, provincia de Viseu, que es uno de los mejor conservados. Se realizaron algunas excavaciones en los años 50. No obstante, las investigaciones sistemáticas comenzaron en 1985. El edificio, de fundación romana, mantiene hasta hoy gran parte de la estructura primitiva, en la que pueden determinarse dos fases constructivas, de las que se dan sus características.We start this report with a general introduction in which the scarcity of studies about ancient thermalism in Portugal, and the bad preservation of the majority of the known ruins, is shown. We continué with the spa of Sao Pedro do Sul, province of Viseu, one of the best preserved. Several diggins were made in the 50's. How^ever, the systematic research started in 1985. The building, of román foundation, maintains today a big portion of its primitive structure, in wich two construction stages can be determined, whose characteristics are discribed here.

  20. Bilateral Renal Vein Thrombosis due to Elevated Factor VIII Levels.

    Science.gov (United States)

    Patole, Shalom; Ramya, I

    2015-08-01

    Recent evidence has shown that high level of factor VIII is associated with increased risk of thromboembolism. High factor VIII levels are associated with a seven-fold increase in the risk of venous thrombosis. Renal vein thrombosis is usually associated with nephrotic syndrome, procoagulant state or oral contraceptive pills. We report a case of a lady who presented with bilateral renal vein thrombosis due to high factor VIII levels and oral contraceptive pills (OCP) use. © Journal of the Association of Physicians of India 2011.

  1. Factoring in Factor VIII With Acute Ischemic Stroke.

    Science.gov (United States)

    Siegler, James E; Samai, Alyana; Albright, Karen C; Boehme, Amelia K; Martin-Schild, Sheryl

    2015-10-01

    There is growing research interest into the etiologies of cryptogenic stroke, in particular as it relates to hypercoagulable states. An elevation in serum levels of the procoagulant factor VIII is recognized as one such culprit of occult cerebral infarctions. It is the objective of the present review to summarize the molecular role of factor VIII in thrombogenesis and its clinical use in the diagnosis and prognosis of acute ischemic stroke. We also discuss the utility of screening for serum factor VIII levels among patients at risk for, or those who have experienced, ischemic stroke. © The Author(s) 2015.

  2. Stark broadening parameter tables for K VIII and K IX

    Directory of Open Access Journals (Sweden)

    Dimitrijević M.S.

    1998-01-01

    Full Text Available Using a semiclassical approach, we have calculated electron−, proton−, and He III−impact line widths and shifts for 4 K VIII and 30 K IX multiplets as a function of temperature and perturber density.

  3. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish.

    Science.gov (United States)

    Aspatwar, Ashok; Tolvanen, Martti E E; Jokitalo, Eija; Parikka, Mataleena; Ortutay, Csaba; Harjula, Sanna-Kaisa E; Rämet, Mika; Vihinen, Mauno; Parkkila, Seppo

    2013-02-01

    Congenital ataxia and mental retardation are mainly caused by variations in the genes that affect brain development. Recent reports have shown that mutations in the CA8 gene are associated with mental retardation and ataxia in humans and ataxia in mice. The gene product, carbonic anhydrase-related protein VIII (CARP VIII), is predominantly present in cerebellar Purkinje cells, where it interacts with the inositol 1,4,5-trisphosphate receptor type 1, a calcium channel. In this study, we investigated the effects of the loss of function of CARP VIII during embryonic development in zebrafish using antisense morpholino oligonucleotides against the CA8 gene. Knockdown of CA8 in zebrafish larvae resulted in a curved body axis, pericardial edema and abnormal movement patterns. Histologic examination revealed gross morphologic defects in the cerebellar region and in the muscle. Electron microscopy studies showed increased neuronal cell death in developing larvae injected with CA8 antisense morpholinos. These data suggest a pivotal role for CARP VIII during embryonic development. Furthermore, suppression of CA8 expression leads to defects in motor and coordination functions, mimicking the ataxic human phenotype. This work reveals an evolutionarily conserved function of CARP VIII in brain development and introduces a novel zebrafish model in which to investigate the mechanisms of CARP VIII-related ataxia and mental retardation in humans.

  4. Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking

    OpenAIRE

    Ebberink, Eduard H T M; Bouwens, Eveline A. M.; Bloem, Esther; Boon-Spijker, Mariëtte; van den Biggelaar, Maartje; Voorberg, Jan; Alexander B. Meijer; Mertens, Koen

    2017-01-01

    Factor VIII C-domains are believed to have specific functions in cofactor activity and in interactions with von Willebrand factor. We have previously shown that factor VIII is co-targeted with von Willebrand factor to the Weibel-Palade bodies in blood outgrowth endothelial cells, even when factor VIII carries mutations in the light chain that are associated with defective von Willebrand factor binding. In this study, we addressed the contribution of individual factor VIII C-domains in intrace...

  5. Usage evaluation of the Physiotherapy Evidence Database (PEDro) among Brazilian physical therapists.

    Science.gov (United States)

    Elkins, Mark R; Moseley, Anne M; Pinto, Rafael Z

    2015-01-01

    It is unclear whether the Physiotherapy Evidence Database (PEDro) is widely and equally used by physical therapists in Brazil. As PEDro is considered a key resource to support evidence-based physical therapy, analyses of PEDro usage could reflect the extent of dissemination of evidence-based practice. To describe the usage of PEDro among the five regions of the World Confederation for Physical Therapy (WCPT) and, in more detail, in the South American region and Brazil over a 5-year period. PEDro home-page sessions and the number of searches performed were logged for a 5-year period (2010-2014). Absolute usage and relative usage were calculated for each region of the WCPT, each country in the South American region of WCPT, and each Regional Council (CREFITO) in Brazil. Europe had the highest absolute and relative usage among the five regions of the WCPT (971 searches per million-population per year), with the South American region ranked 4th in absolute terms and 3rd in relative terms (486). Within the South American region, Brazil accounted for nearly 60% of searches (755). Analysis at a national level revealed that usage per physical therapist in Brazil is very low across all CREFITOs. The highest usage occurred in CREFITO 6 with 1.3 searches per physical therapist per year. PEDro is not widely and equally used throughout Brazil. Strategies to promote PEDro and to make PEDro more accessible to physical therapists speaking Portuguese are needed.

  6. Kirjanikud Pedro Krusten, Henrik Visnapuu ja teised / Edla Krusten ; intervjueerinud Martin Viirand

    Index Scriptorium Estoniae

    Krusten, Edla

    2012-01-01

    Pedro Krusteni lesk Edla Krusten räägib oma käekäigust sõja ajal, Saksamaal ja USA-s, oma abikaasast Pedro Krustenist ja vaimsest atmosfäärist, mis valitses välis-eestlaste seas Ameerika Ühendriikides. Artikkel põhineb Rahvusringhäälingu raadiosaatel "Maailmapilt" (2008)

  7. Usage evaluation of the Physiotherapy Evidence Database (PEDro) among Brazilian physical therapists

    Science.gov (United States)

    Elkins, Mark R.; Moseley, Anne M.; Pinto, Rafael Z.

    2015-01-01

    BACKGROUND: It is unclear whether the Physiotherapy Evidence Database (PEDro) is widely and equally used by physical therapists in Brazil. As PEDro is considered a key resource to support evidence-based physical therapy, analyses of PEDro usage could reflect the extent of dissemination of evidence-based practice. OBJECTIVE: To describe the usage of PEDro among the five regions of the World Confederation for Physical Therapy (WCPT) and, in more detail, in the South American region and Brazil over a 5-year period. METHOD: PEDro home-page sessions and the number of searches performed were logged for a 5-year period (2010-2014). Absolute usage and relative usage were calculated for each region of the WCPT, each country in the South American region of WCPT, and each Regional Council (CREFITO) in Brazil. RESULTS: Europe had the highest absolute and relative usage among the five regions of the WCPT (971 searches per million-population per year), with the South American region ranked 4th in absolute terms and 3rd in relative terms (486). Within the South American region, Brazil accounted for nearly 60% of searches (755). Analysis at a national level revealed that usage per physical therapist in Brazil is very low across all CREFITOs. The highest usage occurred in CREFITO 6 with 1.3 searches per physical therapist per year. CONCLUSIONS: PEDro is not widely and equally used throughout Brazil. Strategies to promote PEDro and to make PEDro more accessible to physical therapists speaking Portuguese are needed. PMID:26443980

  8. Yupingfeng San

    Science.gov (United States)

    Liu, Xue; Shen, Jiawen; Fan, Danping; Qiu, Xuemei; Guo, Qingqing; Zheng, Kang; Luo, Hui; Shu, Jun; Lu, Cheng; Zhang, Ge; Lu, Aiping; Ma, Chaoying; He, Xiaojuan

    2017-01-01

    Yupingfeng San (YPFS) is a representative Traditional Chinese Medicine (TCM) formula with accepted therapeutic effect on Asthma. However, its action mechanism is still obscure. In this study, we used network pharmacology to explore potential mechanism of YPFS on asthma. Nucleotide-binding oligomerization domain (NOD)-like receptor pathway was shown to be the top one shared signaling pathway associated with both YPFS and asthma. In addition, NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome was treated as target protein in the process of YPFS regulating asthma. Further, experimental validation was done by using LPS-stimulated U937 cells and ovalbumin (OVA)-sensitized BALB/c mice model. In vitro experiments showed that YPFS significantly decreased the production of TNF-α and IL-6, as well as both mRNA and protein levels of IL-1β, NLRP3, Caspase-1 and ASC in LPS-stimulated U937 cells. In vivo experiment indicated that YPFS treatment not only attenuated the clinical symptoms, but also reduced inflammatory cell infiltration, mucus secretion and MUC5AC production in lung tissue of asthmatic mice. Moreover, YPFS treatment remarkably decreased the mRNA and protein levels of IL-1β, NLRP3, Caspase-1 and ASC in lung tissue of asthmatic mice. In conclusion, these results demonstrated that YPFS could inhibit NLRP3 inflammasome components to attenuate the inflammatory response in asthma.

  9. AAV5-Factor VIII Gene Transfer in Severe Hemophilia A.

    Science.gov (United States)

    Rangarajan, Savita; Walsh, Liron; Lester, Will; Perry, David; Madan, Bella; Laffan, Michael; Yu, Hua; Vettermann, Christian; Pierce, Glenn F; Wong, Wing Y; Pasi, K John

    2017-12-28

    Patients with hemophilia A rely on exogenous factor VIII to prevent bleeding in joints, soft tissue, and the central nervous system. Although successful gene transfer has been reported in patients with hemophilia B, the large size of the factor VIII coding region has precluded improved outcomes with gene therapy in patients with hemophilia A. We infused a single intravenous dose of a codon-optimized adeno-associated virus serotype 5 (AAV5) vector encoding a B-domain-deleted human factor VIII (AAV5-hFVIII-SQ) in nine men with severe hemophilia A. Participants were enrolled sequentially into one of three dose cohorts (low dose [one participant], intermediate dose [one participant], and high dose [seven participants]) and were followed through 52 weeks. Factor VIII activity levels remained at 3 IU or less per deciliter in the recipients of the low or intermediate dose. In the high-dose cohort, the factor VIII activity level was more than 5 IU per deciliter between weeks 2 and 9 after gene transfer in all seven participants, and the level in six participants increased to a normal value (>50 IU per deciliter) that was maintained at 1 year after receipt of the dose. In the high-dose cohort, the median annualized bleeding rate among participants who had previously received prophylactic therapy decreased from 16 events before the study to 1 event after gene transfer, and factor VIII use for participant-reported bleeding ceased in all the participants in this cohort by week 22. The primary adverse event was an elevation in the serum alanine aminotransferase level to 1.5 times the upper limit of the normal range or less. Progression of preexisting chronic arthropathy in one participant was the only serious adverse event. No neutralizing antibodies to factor VIII were detected. The infusion of AAV5-hFVIII-SQ was associated with the sustained normalization of factor VIII activity level over a period of 1 year in six of seven participants who received a high dose, with

  10. Idiopathic Acquired Hemophilia A with Undetectable Factor VIII Inhibitor

    Directory of Open Access Journals (Sweden)

    Nicholas B. Abt

    2014-01-01

    Full Text Available Objective. We present the case of a 73-year-old female, with no family or personal history of a bleeding disorder, who had a classic presentation for acquired hemophilia A. Factor VIII activity was low but detectable and a factor VIII inhibitor was undetectable. Methods. The patient’s plasma was comprehensively studied to determine the cause of the acquired coagulopathy. Using the Nijmegen modification of the Bethesda assay, no factor VIII autoantibody was measureable despite varying the incubation time from 1 to 3 hours. Results. The aPTT was prolonged at 46.8 seconds, which did not correct in the 4 : 1 mix but did with 1 : 1 mix. Using a one stage factor VIII activity assay, the FVIII activity was 16% and chromogenic FVIII activity was also 16%. The patient was treated with recombinant FVII and transfusion, significantly reducing bleeding. Long-term therapy was initiated with cyclophosphamide and prednisone with normalization of FVIII activity. Conclusions. Physicians can be presented with the challenging clinical picture of an acquired factor VIII inhibitor without a detectable inhibitor by the Bethesda assay. Standard therapy for an acquired hemophilia A should be considered.

  11. Quality, language, subdiscipline and promotion were associated with article accesses on Physiotherapy Evidence Database (PEDro).

    Science.gov (United States)

    Yamato, Tiê P; Arora, Mohit; Stevens, Matthew L; Elkins, Mark R; Moseley, Anne M

    2018-03-01

    To quantify the relationship between the number of times articles are accessed on the Physiotherapy Evidence Database (PEDro) and the article characteristics. A secondary aim was to examine the relationship between accesses and the number of citations of articles. The study was conducted to derive prediction models for the number of accesses of articles indexed on PEDro from factors that may influence an article's accesses. All articles available on PEDro from August 2014 to January 2015 were included. We extracted variables relating to the algorithm used to present PEDro search results (research design, year of publication, PEDro score, source of systematic review (Cochrane or non-Cochrane)) plus language, subdiscipline of physiotherapy, and whether articles were promoted to PEDro users. Three predictive models were examined using multiple regression analysis. Citation and journal impact factor were downloaded. There were 29,313 articles indexed in this period. We identified seven factors that predicted the number of accesses. More accesses were noted for factors related to the algorithm used to present PEDro search results (synthesis research (i.e., guidelines and reviews), recent articles, Cochrane reviews, and higher PEDro score) plus publication in English and being promoted to PEDro users. The musculoskeletal, neurology, orthopaedics, sports, and paediatrics subdisciplines were associated with more accesses. We also found that there was no association between number of accesses and citations. The number of times an article is accessed on PEDro is partly predicted by how condensed and high quality the evidence it contains is. Copyright © 2017 Chartered Society of Physiotherapy. Published by Elsevier Ltd. All rights reserved.

  12. La experienciadel sujeto cultural en la Murga de Pedro Orgambide

    Directory of Open Access Journals (Sweden)

    Amelia Royo

    2003-12-01

    Full Text Available Cuando el objeto es tan recortado lo importante es plantear el propósito en términos de la pertenencia del texto a un corpus. En este caso me ha interesado Pedro Orgambide en el marco de un conjunto de autores que, contemporánea o anacrónicamente, han ingresado el Día de la Lealtad a la escritura literaria. En trabajos anteriores relevé autores como Borges, Martínez Estrada y Lamborghini que, en mayor o menor medida, textualizan el episodio del 17 de octubre de 1945, fecha en que "una cosa terminaba y otra empezaba", como expresa una novela de aquel entonces.

  13. Pedro García y el color del vidrio

    Directory of Open Access Journals (Sweden)

    María Teresa González Vicario

    1999-01-01

    Full Text Available El vidrio es uno de los materiales que ha alcanzado una dimensión escultórica en el siglo XX. Fue a mediados de este siglo, aproximadamente, cuando tuvo lugar su incorporación a la escultura contemporánea, y aunque España se ha sumado con un cierto retraso a esta nueva vertiente del lengueje escultórico, no son pocos los nombres de escultores que podrían ser citados por haber descubierto las posibilidades que el vidrio encierra como material escultórico. Uno de ellos es Pedro García, quien ha encontrado en el vidrio laminado, un material de procedencia industrial, su medio de expresión plástica. El análisis de su evolución artística hasta el momento actual constituye el objeto de este artículo, para lo cual se ha partido de unas primeras obras que obedecen a un planteamiento constructivo, racionalista, y en las que el vidrio ha sido trabajado en frío.The apparition of glass as a new material in sculpture dates from the middle of the XXth century. Spain has incorporated the sculptoric possibilities of glass later than other countries, but it has had an important following by an important group of sculptors. One of them is Pedro García, who has found in laminated glass, an industrial type of glass, his chief inspiration. This article traces the history of his artistic evolution. In the beginning his sculptures were very constructive and rational. Later, he developed a special technique working on glass in the process of formation through heat.

  14. San Mateo Creek Basin

    Science.gov (United States)

    The San Mateo Creek Basin comprises approximately 321 square miles within the Rio San Jose drainage basin in McKinley and Cibola counties, New Mexico. This basin is located within the Grants Mining District (GMD).

  15. La encrucijada en Pedro Páramo de Juan Rulfo / The Crossroads in Pedro Páramo by Juan Rulfo

    Directory of Open Access Journals (Sweden)

    Lilia Leticia García-Peña

    2015-08-01

    Full Text Available La obra de Juan Rulfo sintetiza la realidad del campo mexicano, captura el contorno de las identidades individuales y de la estructura de la interacción social del mundo que tanto le preocupó y del que es intérprete indiscutible, pero también supo convertir en materia narrativa aquellas atmósferas que rebasan el contexto mexicano y social. En este trabajo abordaré el tema de la encrucijada en el imaginario simbólico de Pedro Páramo (1955 como expresión de una reelaboración del mito de Hermes, analizaré cómo la novela de Juan Rulfo muestra estos ecos herméticos y qué sentido estético y sociocultural tiene esta resonancia mítica.

  16. Igor Zabel 14. VIII 1958 - 23. VII 2005

    Index Scriptorium Estoniae

    2005-01-01

    Igor Zabel oli Ida-Euroopa tuntumaid kunstiteoreetikuid ja kuraatoreid. Töötas 1986. aastast Ljubljana moodsa kunsti muuseumi kuraatorina. 9. VIII avatakse seal viimane I. Zabeli kureeritud näitus "Territories, Identities, Nets-Slovene Art 1995-2005"

  17. What history tells us VIII. The progressive construction of a ...

    Indian Academy of Sciences (India)

    2007-02-09

    Feb 9, 2007 ... Home; Journals; Journal of Biosciences; Volume 32; Issue 2. What history tells us VIII. The progressive construction of a mechanism for prion diseases. Michel Morange. Series Volume 32 Issue 2 March 2007 pp 223-227. Fulltext. Click here to view fulltext PDF. Permanent link:

  18. The labour ward analgesic service at King Edward VIII Hospital ...

    African Journals Online (AJOL)

    dence of shivering9 and an improved sense of maternal well-being.lo. In summary, the study presented here shows that the analgesia service provided ro the labour ward at King. Edward VIII Hospital is at present grossly inadequate. In particular, a high proportion (76%) of mothers with a specific indication for epidural ...

  19. Functional regions in coagulation factor VIII explored by mass spectrometry

    NARCIS (Netherlands)

    Bloem, E.

    2013-01-01

    The molecular mechanisms behind the function of factor VIII (FVIII) have remained poorly understood. FVIII acts in the blood coagulation cascade as cofactor for activated factor IX (FIXa) in the membrane bound activated factor X generating (FXase) complex. A functional absence in FVIII leads to the

  20. Comparison of factor VIII transgenes bioengineered for improved expression in gene therapy of hemophilia A.

    Science.gov (United States)

    Dooriss, Kerry L; Denning, Gabriela; Gangadharan, Bagirath; Javazon, Elisabeth H; McCarty, David A; Spencer, H Trent; Doering, Christopher B

    2009-05-01

    Successful gene therapy of hemophilia A depends on the sustained expression of therapeutic levels of factor VIII (fVIII). Because of mRNA instability, interactions with resident endoplasmic reticulum (ER) chaperones, and the requirement for carbohydrate-facilitated transport from the ER to the Golgi apparatus, fVIII is expressed at much lower levels from mammalian cells than other proteins of similar size and complexity. A number of bioengineered forms of B domain-deleted (BDD) human fVIII have been generated and shown to have enhanced expression. Previously, we demonstrated that recombinant BDD porcine fVIII exhibits high-level expression due to specific sequence elements that increase biosynthesis via enhanced posttranslational transit through the secretory pathway. In the current study, high-expression recombinant fVIII constructs were compared directly in order to determine the relative expression of the various bioengineered fVIII transgenes. The data demonstrate that BDD porcine fVIII expression is superior to that of any of the human fVIII variant constructs tested. Mean fVIII expression of 18 units/10(6) cells/24 hr was observed from HEK-293 cells expressing a single copy of the porcine fVIII transgene, which was 36- to 225-fold greater than that of any human fVIII transgene tested. Furthermore, greater than 10-fold higher expression was observed in human cells transduced with BDD porcine fVIII versus BDD human fVIII-encoding lentiviral vectors, even at low proviral copy numbers, supporting its use over other human fVIII variants in future hemophilia A gene therapy clinical trials.

  1. 77 FR 21556 - Don Pedro Hydroelectric Project: Turlock Irrigation District; Modesto Irrigation District...

    Science.gov (United States)

    2012-04-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Don Pedro Hydroelectric Project: Turlock Irrigation District; Modesto Irrigation District; Supplement to Notice of Study Dispute Resolution Technical Conference On March 16, 2012...

  2. PEDro or Cochrane to Assess the Quality of Clinical Trials? A Meta-Epidemiological Study.

    Science.gov (United States)

    Armijo-Olivo, Susan; da Costa, Bruno R; Cummings, Greta G; Ha, Christine; Fuentes, Jorge; Saltaji, Humam; Egger, Matthias

    2015-01-01

    There is debate on how the methodological quality of clinical trials should be assessed. We compared trials of physical therapy (PT) judged to be of adequate quality based on summary scores from the Physiotherapy Evidence Database (PEDro) scale with trials judged to be of adequate quality by Cochrane Risk of Bias criteria. Meta-epidemiological study within Cochrane Database of Systematic Reviews. Meta-analyses of PT trials were identified in the Cochrane Database of Systematic Reviews. For each trial PeDro and Cochrane assessments were extracted from the PeDro and Cochrane databases. Adequate quality was defined as adequate generation of random sequence, concealment of allocation, and blinding of outcome assessors (Cochrane criteria) or as trials with a PEDro summary score ≥5 or ≥6 points. We combined trials of adequate quality using random-effects meta-analysis. Forty-one Cochrane reviews and 353 PT trials were included. All meta-analyses included trials with PEDro scores ≥5, 37 (90.2%) included trials with PEDro scores ≥6 and only 22 (53.7%) meta-analyses included trials of adequate quality according to the Cochrane criteria. Agreement between PeDro and Cochrane was poor for PeDro scores of ≥5 points (kappa = 0.12; 95% CI 0.07 to 0.16) and slight for ≥6 points (kappa 0.24; 95% CI 0.16-0.32). When combining effect sizes of trials deemed to be of adequate quality according to PEDro or Cochrane criteria, we found that a substantial difference in the combined effect size (≥0.15) was evident in 9 (22%) out of the 41 meta-analyses for PEDro cutoff ≥5 and 10 (24%) for cutoff ≥6. The PeDro and Cochrane approaches lead to different sets of trials of adequate quality, and different combined treatment estimates from meta-analyses of these trials. A consistent approach to assessing RoB in trials of physical therapy should be adopted.

  3. PEDro or Cochrane to Assess the Quality of Clinical Trials? A Meta-Epidemiological Study.

    Directory of Open Access Journals (Sweden)

    Susan Armijo-Olivo

    Full Text Available There is debate on how the methodological quality of clinical trials should be assessed. We compared trials of physical therapy (PT judged to be of adequate quality based on summary scores from the Physiotherapy Evidence Database (PEDro scale with trials judged to be of adequate quality by Cochrane Risk of Bias criteria.Meta-epidemiological study within Cochrane Database of Systematic Reviews.Meta-analyses of PT trials were identified in the Cochrane Database of Systematic Reviews. For each trial PeDro and Cochrane assessments were extracted from the PeDro and Cochrane databases. Adequate quality was defined as adequate generation of random sequence, concealment of allocation, and blinding of outcome assessors (Cochrane criteria or as trials with a PEDro summary score ≥5 or ≥6 points. We combined trials of adequate quality using random-effects meta-analysis.Forty-one Cochrane reviews and 353 PT trials were included. All meta-analyses included trials with PEDro scores ≥5, 37 (90.2% included trials with PEDro scores ≥6 and only 22 (53.7% meta-analyses included trials of adequate quality according to the Cochrane criteria. Agreement between PeDro and Cochrane was poor for PeDro scores of ≥5 points (kappa = 0.12; 95% CI 0.07 to 0.16 and slight for ≥6 points (kappa 0.24; 95% CI 0.16-0.32. When combining effect sizes of trials deemed to be of adequate quality according to PEDro or Cochrane criteria, we found that a substantial difference in the combined effect size (≥0.15 was evident in 9 (22% out of the 41 meta-analyses for PEDro cutoff ≥5 and 10 (24% for cutoff ≥6.The PeDro and Cochrane approaches lead to different sets of trials of adequate quality, and different combined treatment estimates from meta-analyses of these trials. A consistent approach to assessing RoB in trials of physical therapy should be adopted.

  4. Os primeiros filmes de Joaquim Pedro de Andrade: história e linguagem

    Directory of Open Access Journals (Sweden)

    Tatiana Pontes de Oliveira

    2014-12-01

    Full Text Available The early films by Joaquim Pedro de Andrade: history and language – Joaquim Pedro de Andrade: primeiros tempos (early days four films by this “Cinema Novo” director are analyzed. From a historical research, the analysis focus is on this filmmaker’s training period and his initial films. His reflections on relations between fiction cinema and documentary, besides the specificities of the cinematographic language are highlighted.

  5. Usage evaluation of the Physiotherapy Evidence Database (PEDro among Brazilian physical therapists

    Directory of Open Access Journals (Sweden)

    Mark R. Elkins

    2015-08-01

    Full Text Available BACKGROUND: It is unclear whether the Physiotherapy Evidence Database (PEDro is widely and equally used by physical therapists in Brazil. As PEDro is considered a key resource to support evidence-based physical therapy, analyses of PEDro usage could reflect the extent of dissemination of evidence-based practice.OBJECTIVE: To describe the usage of PEDro among the five regions of the World Confederation for Physical Therapy (WCPT and, in more detail, in the South American region and Brazil over a 5-year period.METHOD: PEDro home-page sessions and the number of searches performed were logged for a 5-year period (2010-2014. Absolute usage and relative usage were calculated for each region of the WCPT, each country in the South American region of WCPT, and each Regional Council (CREFITO in Brazil.RESULTS: Europe had the highest absolute and relative usage among the five regions of the WCPT (971 searches per million-population per year, with the South American region ranked 4th in absolute terms and 3rd in relative terms (486. Within the South American region, Brazil accounted for nearly 60% of searches (755. Analysis at a national level revealed that usage per physical therapist in Brazil is very low across all CREFITOs. The highest usage occurred in CREFITO 6 with 1.3 searches per physical therapist per year.CONCLUSIONS: PEDro is not widely and equally used throughout Brazil. Strategies to promote PEDro and to make PEDro more accessible to physical therapists speaking Portuguese are needed.

  6. TT virus contaminates first-generation recombinant factor VIII concentrates.

    Science.gov (United States)

    Azzi, A; De Santis, R; Morfini, M; Zakrzewska, K; Musso, R; Santagostino, E; Castaman, G

    2001-10-15

    Recombinant factor VIII and factor IX concentrates, human-plasma-derived albumin, and samples from previously untreated patients with hemophilia were examined for the presence of TT virus (TTV) by using polymerase chain reaction testing. Blood samples from the patients were obtained prospectively before and every 3 to 6 months after therapy was begun. TTV was detected in 23.5% of the recombinant-product lots and 55.5% of the albumin lots tested. Only first-generation factor VIII recombinant concentrates stabilized with human albumin were positive for TTV, whereas all second-generation (human protein-free) concentrates were negative for the virus. In 59% of patients treated with either first- or second-generation recombinant factor concentrates, TTV infection developed at some point after the initial infusion. Infection with TTV in these patients before and after treatment did not appear to be clinically important. Thus, first-generation recombinant factor VIII concentrates may contain TTV and the source of the viral contamination may be human albumin.

  7. SAN CARLOS APACHE PAPERS.

    Science.gov (United States)

    ROESSEL, ROBERT A., JR.

    THE FIRST SECTION OF THIS BOOK COVERS THE HISTORICAL AND CULTURAL BACKGROUND OF THE SAN CARLOS APACHE INDIANS, AS WELL AS AN HISTORICAL SKETCH OF THE DEVELOPMENT OF THEIR FORMAL EDUCATIONAL SYSTEM. THE SECOND SECTION IS DEVOTED TO THE PROBLEMS OF TEACHERS OF THE INDIAN CHILDREN IN GLOBE AND SAN CARLOS, ARIZONA. IT IS DIVIDED INTO THREE PARTS--(1)…

  8. Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin

    Energy Technology Data Exchange (ETDEWEB)

    Hill-Eubanks, D.C.; Parker, C.G.; Lollar, P. (Univ. of Vermont, Burlington (USA))

    1989-09-01

    Blood coagulation factor VIII (fVIII) is a plasma protein that is decreased or absent in hemophilia A. It is isolated as a mixture of heterodimers that contain a variably sized heavy chain and a common light chain. Thrombin catalyzes the activation of fVIII in a reaction that is associated with cleavages in both types of chain. The authors isolated a serine protease from Bothrops jararacussu snake venom that catalyzes thrombin-like heavy-chain cleavage but not light-chain cleavage in porcine fVIII as judged by NaDodSO{sub 4}/PAGE and N-terminal sequence analysis. Using a plasma-free assay of the ability of activated {sup 125}I-fVIII to function as a cofactor in the activation of factor X by factor IXa, they found that fVIII is activated by the venom enzyme. The venom enzyme-activated fVIII was isolated in stable form by cation-exchange HPLC. von Willebrand factor inhibited venom enzyme-activated fVIII but not thrombin-activated fVIII. These results suggest that the binding of fVIII to von Willebrand factor depends on the presence of an intact light chain and that activated fVIII must dissociate from von Willebrand factor to exert its cofactor effect. Thus, proteolytic activation of fVIII-von Willebrand factor complex appears to be differentially regulated by light-chain cleavage to dissociate the complex and heavy-chain cleavage to activate the cofactor function.

  9. 40 CFR Appendix Viii to Part 600 - Fuel Economy Label Formats

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Fuel Economy Label Formats VIII... POLICY FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Pt. 600, App. VIII Appendix VIII to Part 600—Fuel Economy Label Formats EC01MY92.117 EC01MY92.118 EC01MY92.119 EC01MY92.120...

  10. Localization of collagen type VIII in normal and pathological human cornea

    OpenAIRE

    Zenklová, Kateřina

    2007-01-01

    The aim of this work was to localize collagen type VIII in different layers of the cornea and to compare it's localization in normal corneas with pathological corneas obtained from patients with Fuchs endothelial dystrophy, posterior polymorphous dystrophy or keratoconus.The only comercially available antibody did not proove sufficient specifiky for collagen type VIII. With use of the antibody 9H3 anti alCVIII was collagen VIII evidenced in the cornea. This antibody can be used for detection ...

  11. Differential proteolytic activation of factor VIII-von Willebrand factor complex by thrombin.

    OpenAIRE

    Hill-Eubanks, D C; Parker, C G; Lollar, P

    1989-01-01

    Blood coagulation factor VIII (fVIII) is a plasma protein that is decreased or absent in hemophilia A. It is isolated as a mixture of heterodimers that contain a variably sized heavy chain and a common light chain. Thrombin catalyzes the activation of fVIII in a reaction that is associated with cleavages in both types of chain. We isolated a serine protease from Bothrops jararacussu snake venom that catalyzes thrombin-like heavy-chain cleavage but not light-chain cleavage in porcine fVIII as ...

  12. The Emperor Dom Pedro II: his convulsive seizures when a boy O imperador Dom Pedro II: as suas crises convulsivas quando menino

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2007-12-01

    Full Text Available INTRODUCTION: Dom Pedro II, the Prince Heir and Emperor under regency, in a delicate period of the construction of the Brazilian nation, had convulsive seizures. OBJECTIVE: To investigate the convulsive seizures and related syndromes of Dom Pedro II and his family, besides the physicians in charge of the health care. METHOD: Narrative review based on primary and secondary sources. CONCLUSION: The scattered and self-limited convulsive seizures associated with physical and mental integrity favored a benign prognosis. Dom Pedro and his family presented rich history of epileptic seizures and febrile convulsion. This variety resembles the diagnosis of generalized epilepsy with febrile seizures plus that seems to be a combination of several syndromes with shared genetic susceptibility.INTRODUÇÃO: Dom Pedro, o príncipe herdeiro e imperador sob regência, em período delicado da formação da nação brasileira, apresentou crises convulsivas que geraram preocupação para o país. OBJETIVO: Investigar a história da epilepsia de Dom Pedro II e da sua família e procurar identificar quais tipos de crises epilépticas estavam presentes, além dos médicos envolvidos com os cuidados de saúde. MÉTODO: Revisão narrativa baseada em fontes primárias e secundárias. CONCLUSÃO: As crises convulsivas esparsas e auto-limitadas associadas a higidez física e mental de Dom Pedro II sugerem um prognóstico benigno. A história de epilepsia idiopática e convulsões febris no imperador e em outros membros da sua família aponta para o diagnóstico mais provável de Epilepsia Generalizada com Convulsões Febris Plus que é determinada por uma combinação de alguns tipos de manifestações epilépticas com suscetibilidade genética compartilhada.

  13. Epileptic seizures in a descendant of Dom Pedro I Crises epilépticas em uma descendente de Dom Pedro I

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2010-04-01

    Full Text Available Intrauterine seizure is a rare event. Genetic predisposition and trauma are possible risk factors. OBJECTIVE: To review and comment on the historical description of intrauterine events of a bastard daughter of Dom Pedro I (Maria Isabel Alcântara Brasileira - 1830-1896. METHOD: Review of historical facts about the health of Dom Pedro I's daughter according to primary and secondary historical data. RESULTS: According to historical accounts, Dom Pedro I's daughter suffered trauma during the intrauterine period that provoked intrauterine seizures. At the age of eight years, she developed self-limited and benign generalized epilepsy. Like her father, she had mood problems and also learning difficulties. CONCLUSION: Dona Maria Isabel's own report does not shown sufficient evidence to support the diagnosis of post-traumatic intrauterine seizures. Nevertheless, her family history suggests a genetic basis for her epilepsy.A convulsão intra-uterina é evento raro, sendo possíveis fatores de risco a genética e o traumatismo. OBJETIVO: Rever e comentar a descrição histórica de eventos intra-uterinas de uma filha bastarda de D. Pedro I (Maria Isabel Alcântara Brasileira - 1830-1896. MÉTODO: Revisão dos fatos históricos sobre a saúde da filha do D. Pedro I, de acordo com dados históricos primários e secundários. RESULTADOS: A filha de Dom Pedro I, de acordo com relatos históricos teria sofrido um traumatismo durante o período intra-uterino, o que provocou convulsões intra-uterinas. Na idade de oito anos a menina desenvolveu uma epilepsia generalizada limitada e benigna. Como seu pai, teve problemas do humor e, também, dificuldades de aprendizagem. CONCLUSÃO: O relato de Dona Maria Isabel não gera prova suficiente para sustentar o diagnóstico de convulsões intra-uterinas de origem traumática. Não obstante, seus antecedentes familiares sugerem uma base genética para sua epilepsia.

  14. Análisis arquitectónico y constructivo de la techumbre en madera policromada de la iglesia de San Antonio Abad de Valencia como pervivencia de la arquitectura tardogótica mediterránea en la Valencia del siglo XV.

    OpenAIRE

    BLANCO GÓMEZ, PEDRO RAFAEL

    2016-01-01

    [EN] ARCHITECTURAL AND CONSTRUCTION OF ROOFING POLYCHROME WOODEN ANALYSIS OF THE CHURCH OF SAN ANTONIO ABAD DE VALENCIA, SURVIVAL OF ARCHITECTURE AS TARDOGÓTICA VALENCIA MEDITERRANEAN FIFTEENTH CENTURY Author of the thesis: Pedro Rafael Blanco Gómez DIRECTOR OF THE THESIS: Dr. D Javier Benlloch Marco ABSTRACT The object of this thesis is the study of Gothic Mudejar roof of the church of San Antonio Abad in Valencia, located on the street 188 Sagunto Valencia. The deepening of t...

  15. Restauración del Santuario Diocesano de San José de Minas

    OpenAIRE

    López Ulloa, Fabián

    2000-01-01

    El Santuario Diocesano de Nuestra Señora de la Caridad de San José de Minas, forma parte de una importante lista de edificios religiosos diseñados por el Padre Pedro Brüning, renombrado arquitecto oficial de la curia de Quito de finales del siglo XIX y comienzos del XX. El templo de estilo neorománico se yergue imponente sobre la cordillera que forma el nudo de Mojanda en la sierra norte del Ecuador. El presente artículo lo describe y trata sobre la intervención realizada en su restauració...

  16. From Golden Age Mexican Cinema to Transnational Border Feminism: The Community of Spectators in "Loving Pedro Infante"

    Science.gov (United States)

    Heredia, Juanita

    2008-01-01

    The novel "Loving Pedro Infante" by Chicana writer Denise Chavez provides an insightful transcultural feminist critique of Golden Age Mexican cinema culture through a careful examination of gender roles. In the novel, the reception of Pedro Infante's films by spectators bridges generations and national spaces and leads to the formation…

  17. ESPOSAS Y MADRES: LA SEXUALIDAD FEMENINA EN PEDRO PÁRAMO

    Directory of Open Access Journals (Sweden)

    DULCE ISABEL AGUIRRE BARRERA

    2008-01-01

    Full Text Available El presente artículo analiza las manifestaciones de la sexualidad de seis personajes femeninos en Pedro Páramo, de Juan Rulfo (Dolores Preciado, la madre de Pedro Páramo, Eduviges Dyada, Dorotea, Justina Díaz y Damiana Cisneros, en relación con los dos roles sexuados (esposa y madre asociados con el Deber-Ser femenino arquetípico de la ideología androcéntrica, con el propósito de estudiar las diferentes "recreaciones" y/o "transgresiones" de dichos roles en cada uno de los casos.

  18. War and peace: Factor VIII and the adaptive immune response.

    Science.gov (United States)

    Georgescu, Maria T; Lai, Jesse D; Hough, Christine; Lillicrap, David

    2016-03-01

    The development of neutralizing anti-factor VIII (FVIII) antibodies (inhibitors) remains a major challenge for FVIII replacement therapy in hemophilia A patients. The adaptive immune response plays a crucial role in the development and maintenance of inhibitors. In this review, we focus on our current understanding of FVIII interactions with cells of the adaptive immune system and the phenotype of the resultant response. Additionally, we examine both current and novel FVIII tolerance induction methods that function at the level of the adaptive immune response. Copyright © 2015 Elsevier Inc. All rights reserved.

  19. Factor VIII therapy for hemophilia A: current and future issues.

    Science.gov (United States)

    Aledort, Louis; Ljung, Rolf; Mann, Kenneth; Pipe, Steven

    2014-06-01

    Hemophilia A is a congenital, recessive, X-linked bleeding disorder that is managed with infusions of plasma-derived or recombinant factor (F) VIII. The primary considerations in FVIII replacement therapy today are the: 1) immunogenicity of FVIII concentrates, 2) role of longer-acting FVIII products, 3) prophylactic use of FVIII in children and adults with severe hemophilia A, and 4) affordability and availability of FVIII products. Improving patient outcomes by increasing the use of FVIII prophylaxis, preventing or eliminating FVIII inhibitors, and expanding access to FVIII concentrates in developing countries are the major challenges confronting clinicians who care for patients with hemophilia A.

  20. Factor VIII and transmissible spongiform encephalopathy: the case for safety.

    Science.gov (United States)

    Cervenakova, L; Brown, P; Hammond, D J; Lee, C A; Saenko, E L

    2002-03-01

    Haemophilia A is the most common inherited bleeding disorder, caused by a deficiency in coagulation factor VIII (FVIII). Current treatment of haemophilia A is based on repeated infusions of plasma-derived FVIII concentrate or of recombinant FVIII, which may be exposed to plasma-derived material of human or animal origin used in its tissue culture production process. We review epidemiological and experimental studies relevant to blood infectivity in the transmissible spongiform encephalopathies (TSEs, or 'prion' diseases), and evaluate the hypothetical risk of TSE transmission through treatment with plasma-derived or recombinant FVIII.

  1. PENERAPAN METODE PENEMUAN TERBIMBING DI KELAS VIII SMP

    Directory of Open Access Journals (Sweden)

    Toni Hidayat

    2017-08-01

    Full Text Available This study was a classroom action research which aims to investigate how the implementation of guided discovery learning can improve students’ activeness and attainment in the class VIII of Laboraturium UM Senior High School Malang city. The study subject was Class VIII that consists of 36 students, year 2016/2017. This study consisted of two cycles, and the data was collected from the result of the final test, observation, and interview. Based on the research of cycle I, the students’ activeness with mean scores of the meeting I, II, III was 78.88%, 79%, 86.6% respectively. The students’ activeness on cycle II, the mean scores of analyst meeting V and VI were 89.22% and 92.24% respectively. The result of Mathematics learning was increased, it is shown on the test mean of the cycle I that was achieved by 36 students with the percentage of successful learning 83 %. On the cycle test II, the average of 36 gained 82 (score with 7.2 increased from the score mean of the cycle I and with classical mastery learning cycle II 88.88%. Penelitian ini merupakan Penelitian Tindakan Kelas (PTK yang bertujuan untuk mengetahui bagaimana penerapan metode penemuan terbimbing yang dapat meningkatan keaktifan dan hasil belajar siswa kelas VIII SMP Laboratorium UM Kota Malang. Subjek penelitian ini ialah siswa kelas VIII yang berjumlah 36 siswa tahun pelajaran 2016/2017. Penelitian ini terdiri atas dua siklus dan data dikumpulkan dari hasil tes akhir tindakan, observasi, dan wawancara. Berdasarakan hasil penelitian pada siklus I, keaktifan siswa siswa dengan skor rata-rata pertemuan I, II, III adalah 78,88% 79,%, dan 86,6%. Aktivitas siswa pada siklus II, rata-rata skor pengamat pertemuan V dan VI berturut-turut 89,22 % dan 92,24%. Hasil belajar matematika siswa meningkat, hal ini terlihat bahwa rata-rata tes siklus I yang diperoleh 36 siswa sebesar 74,8 dengan presentase keberhasilan belajar 83,33%. Pada tes siklus II rata-rata nilai menjadi 82 dengan

  2. A rare combination: Combined factor V and factor VIII deficiency

    Directory of Open Access Journals (Sweden)

    Başak Ünver Koluman

    2014-06-01

    Full Text Available Combined factor V (FV and factor VIII (FVIII deficiency is a rare factor deficiency with mild-moderate hemorrhage. It is an autosomal recessive coagulation disorder . Prolonged prothrombin time and partial thromboplastic time is characteristic, platelet count remains in normal ranges. The main stay of treatment is to control the hemorrhage. Fresh frozen plasma, desmopressin, specific FVIII concentrates (plasma- derived or recombinant may be used. Being very rare in the general population, we present a case with a combined FV and FVIII deficiency. J Clin Exp Invest 2014; 5 (2: 323-325

  3. Dom Pedro I of Brazil and IV of Portugal epilepsy and peculiar behavior Epilepsia e comportamento peculiar de Dom Pedro I do Brasil e IV de Portugal

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2007-09-01

    Full Text Available We present medical issues related to Dom Pedro de Alcântara Bragança e Bourbon (1798-1834, first Emperor of Brazil. This is made by means of narrative revision on historical facts starting from primary and secondary sources. Dom Pedro presented familiar incidence of epilepsy. His seizures were relatively benign and scattered, supposedly started at the age of 13: idiophatic epilepsy with generalized tonic-clonic seizures only or juvenile myoclonic epilepsy. He also had behavioral disorder characterized by hypersexuality, agitation and impulsiveness. It could have facilitated his opportunistic behavior necessary of daring to transgress the conservatism of the Portuguese crown, to create the constitutional monarchism in Brazil and in Portugal.Apresentamos aspectos médicos relacionadas a Dom Pedro de Alcântara Bragança e Bourbon (1798-1834, primeiro Imperador do Brasil. Isso é feito por meio de revisão narrativa sobre fatos históricos baseados em fontes primárias ou secundárias. Dom Pedro apresentou epilepsia de incidência familiar. Suas crises eram relativamente benignas e esparsas, de início provavelmente aos 13 anos: epilepsia idiopática generalizada com crises tônico-clônicas apenas ou epilepsia mioclônica juvenil. Ele também tinha transtorno do comportamento caracterizado por hipersexualidade, agitação e impulsividade. Isso pode ter facilitado seu comportamento oportunístico necessário para ousar a transgredir o conservadorismo da coroa portuguesa e criar o monarquismo constitucional no Brasil e em Portugal.

  4. Actitudes ambientales de los estudiantes de la Facultad de Educacio?n y Humanidades de la Universidad San Pedro 2011

    OpenAIRE

    Morales Ciudad, Jorge Samuel

    2013-01-01

    Las investigaciones relacionadas al campo ambiental y ma?s especi?ficamente al a?rea de la educacio?n ambiental, toman mucha relevancia debido a la coyuntura planetaria que es de preocupacio?n en todos los sectores de la sociedad. Y ello se manifiesta en el incremento de investigaciones en esta a?rea a nivel mundial y nacional. Pero a nivel local, au?n se esta? empezando a trabajar en ello. De alli? surgio? la necesidad de realizar la presente investigacio?n, la cual tomo? mayor preponderanci...

  5. Environmental Impact Analysis Process. Final Environmental Impact Statement. Air Force, Space Division Housing Project, San Pedro, California

    Science.gov (United States)

    1986-07-24

    Canis latrans Gray Fox U not seen. presence previously Urocyon cinereoargenteus reported by site users Domestic Dog C 2,N Danis Familiaris Domestic Cat 1...and all that it could be. In terms of wildlife habitat, White Point is presently far from barren. It provides space for owls, kestrels, black...the wildlife habitat would be much richer. A Stare Park at White Point would also provide numerous recreational and educational opportunities

  6. UN ACERCAMIENTO A LA REALIDAD EDUCATIVA DE SAN PEDRO CUCUCHUCHO, MICHOACÁN. PASADO, PRESENTE Y FUTURO.

    OpenAIRE

    De Jesús Hipólito, José Emmanuel

    2012-01-01

    Dentro de las sociedades actuales, aquellas que han adoptado una cultura occidental como la nuestra, son pocas las ocasiones en que se permite a los grupos minoritarios o marginados (llámense mujeres, niños, ancianos o indígenas) expresar sus pensamientos, más difícil aún que esos grupos de poder acepten que esas voces tienen el mismo valor que las propias. En el caso de la educación, aunque los discursos y las teorías sitúan al niño como el centro y motor de la labor pedagógic...

  7. Characterization of chemosynthetic microbial mats associated with intertidal hydrothermal sulfur vents in White Point, San Pedro, CA, USA

    Directory of Open Access Journals (Sweden)

    Priscilla J Miranda

    2016-07-01

    Full Text Available The shallow-sea hydrothermal vents at White Point (WP in Palos Verdes (PV on the southern California coast support microbial mats and provide easily accessed settings in which to study chemolithoautotrophic sulfur cycling. Previous studies have cultured sulfur-oxidizing bacteria from the WP mats; however, almost nothing is known about the in situ diversity and activity of the microorganisms in these habitats. We studied the diversity, micron-scale spatial associations and metabolic activity of the mat community via sequence analysis of 16S rRNA and aprA genes, Fluorescence in situ Hybridization (FISH microscopy and sulfate-reduction rate (SRR measurements. Sequence analysis revealed a diverse group of bacteria, dominated by sulfur cycling gamma-, epsilon- and deltaproteobacterial lineages such as Marithrix, Sulfurovum and Desulfuromusa. FISH microscopy suggests a close physical association between sulfur-oxidizing and sulfur-reducing genotypes, while radiotracer studies showed low, but detectable, SRR. Comparative 16S rRNA gene sequence analyses indicate the WP sulfur vent microbial mat community is similar, but distinct from other hydrothermal vent communities representing a range of biotopes and lithologic settings. These findings suggest a complete biological sulfur cycle is operating in the WP mat ecosystem mediated by diverse bacterial lineages, with some similarity with deep-sea hydrothermal vent communities.

  8. Seroprevalence and risk factors of several bovine viral diseases in dairy farms of San Pedro de los Milagros, Antioquia, Colombia

    National Research Council Canada - National Science Library

    Nicolás Fernando Ramírez Vásquez; David Villar Argaiz; Jorge Arturo Fernández Silva; Julián Londoño Pino; Jenny Jovanna Chaparro Gutiérrez; Martha Eufemia Olivera Ángel

    2016-01-01

    .... All farms were up to date on the annual official vaccinations against brucellosis and foot and mouth disease, and 5 out of 29 farms used vaccines against viruses of the bovine respiratory complex...

  9. Disputes over land and water rights in gold mining : The case of Cerro de San Pedro, Mexico

    NARCIS (Netherlands)

    Stoltenborg, D.; Boelens, R.

    2016-01-01

    This article analyzes different visions and positions in a conflict between the developer of an open-pit mine in Mexico and project opponents using the echelons of rights analysis framework, distinguishing four layers of dispute: contested resources; contents of rules and regulations;

  10. Evidence for the formation of sodium hassate(VIII)

    Energy Technology Data Exchange (ETDEWEB)

    Zweidorf, A. von [Inst. fuer Kernchemie, Johannes Gutenberg-Univ. Mainz, Mainz (Germany); Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Angert, R.; Bruechle, W.; Buerger, S.; Eberhardt, K.; Eichler, R.; Hummrich, H.; Jaeger, E.; Kling, H.O.; Kratz, J.V.; Kuczewski, B.; Langrock, G.; Mendel, M.; Rieth, U.; Schaedel, M.; Schausten, B.; Schimpf, E.; Thoerle, P.; Trautmann, N.; Tsukada, K.; Wiehl, N.; Wirth, G.

    2004-07-01

    Hassium, element 108, was produced in the fusion reaction between {sup 26}Mg and {sup 248}Cm. The hassium recoils were oxidized in-situ to a highly volatile oxide, presumably HsO{sub 4}, and were transported in a mixture of He and O{sub 2} to a deposition and detection system. The latter consisted of 16 silicon PIN-photodiodes facing a layer of NaOH, which served, in the presence of a certain partial pressure of water in the transport gas, as reactive surface for the deposition of the volatile tetroxides. Six correlated {alpha}-decay chains of Hs were detected in the first 5 detectors centred around detection position 3. In analogy to OsO{sub 4}, which forms Na{sub 2}[OsO{sub 4}(OH){sub 2}], an osmate(VIII), with aqueous NaOH, HsO{sub 4} presumably was deposited as Na{sub 2}[HsO{sub 4}(OH){sub 2}], a hassate(VIII). (orig.)

  11. Aristóteles y las series causales infinitas en Física VII y VIII

    Directory of Open Access Journals (Sweden)

    Alberto Ross

    2013-11-01

    Full Text Available The aim of this paper is to show that we have at least two different arguments that prove the First Motor's existence. Even though there are coincidences between Physics VII 1 and VIII 5, their arguments are not identical. Physics VII argue the impossibility of an infinite movement in a finite time and VIII 5 the necessity of a "principal" cause.

  12. Effectiveness of Mind Mapping in English Teaching among VIII Standard Students

    Science.gov (United States)

    Hallen, D.; Sangeetha, N.

    2015-01-01

    The aim of the study is to find out the effectiveness of mind mapping technique over conventional method in teaching English at high school level (VIII), in terms of Control and Experimental group. The sample of the study comprised, 60 VIII Standard students in Tiruchendur Taluk. Mind Maps and Achievement Test (Pretest & Posttest) were…

  13. 40 CFR Appendix Viii to Part 85 - Vehicle and Engine Parameters and Specifications

    Science.gov (United States)

    2010-07-01

    .... a. Control parameters and calibrations. b. EGR valve flow calibration. 3. Catalytic converter system.... a. Control parameters and calibrations. b. EGR valve flow calibration. 3. Catalytic converter system... Specifications VIII Appendix VIII to Part 85 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED...

  14. 40 CFR Appendix Viii to Part 266 - Organic Compounds for Which Residues Must Be Analyzed

    Science.gov (United States)

    2010-07-01

    ... AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR THE MANAGEMENT OF SPECIFIC HAZARDOUS WASTES AND SPECIFIC TYPES OF HAZARDOUS WASTE MANAGEMENT FACILITIES Pt. 266, App. VIII Appendix VIII to Part 266... residues collected from areas downstream of the combustion chamber (e.g., ductwork, boiler tubes, heat...

  15. The Educational Ideas of Pedro Arrupe, SJ: A Valuable Resource for All Catholic Educators

    Science.gov (United States)

    Meyo, Obwanda Stephen

    2014-01-01

    Pedro Arrupe was concerned about the growing attitude in which the vocation of humankind is understood as making oneself the centre of the universe, fearing that it has infiltrated into education and schools. Consequently, he set out to counteract this egoistic mindset by propounding an approach to education rooted in justice tempered with faith,…

  16. Reedición de Pedro Henríquez Ureña

    OpenAIRE

    Guerrero Guerrero, Eva

    2012-01-01

    Es referencia bibliográfica de: Historia cultural y literaria de la América hispánica. Corrientes literarias en la América Hispánica / Pedro Henríquez Ureña ; edición y estudio preliminar de Vicente Cervera Salinas

  17. The Reliability of Methodological Ratings for speechBITE Using the PEDro-P Scale

    Science.gov (United States)

    Murray, Elizabeth; Power, Emma; Togher, Leanne; McCabe, Patricia; Munro, Natalie; Smith, Katherine

    2013-01-01

    Background: speechBITE (http://www.speechbite.com) is an online database established in order to help speech and language therapists gain faster access to relevant research that can used in clinical decision-making. In addition to containing more than 3000 journal references, the database also provides methodological ratings on the PEDro-P (an…

  18. More on "Arabic Linguistic Terminology in Pedro de Alcalá"

    NARCIS (Netherlands)

    Zwartjes, O.

    2014-01-01

    The main purpose of this paper is to analyze Spanish linguistic terms and their translations into Arabic in Pedro de Alcalá’s (c.1455-post 1505) Vocabulista arauiga en letra castellana, the first printed missionary Spanish-Arabic dictionary, which appeared together with his Arte para ligeramente

  19. Perfiles anhelados. Correspondencia de lenguajes y estéticas entre el Cementerio Museo San Pedro y la red social Facebook /Desired profiles. Languages and aesthetic correspondence between the San Pedro Cemetery Museum and Facebook social network/Perfis anelados. Correspondência de linguagens e estéticas entre o Cemitério San Pedro e a rede social Facebook

    National Research Council Canada - National Science Library

    Eloisa Lamilla Guerrero

    2016-01-01

    ... características de la red social Facebook. Esta correspondencia entre el lenguaje virtual y el ritual rebasa la mera casualidad, por lo que se propone una lectura comparativa de estos dos universos...

  20. Género, etnia y participación política en San Pedro y San Pablo Ayutla, Oaxaca. Una primera aproximación

    Directory of Open Access Journals (Sweden)

    Verónica Vázquez García

    2013-01-01

    Full Text Available Oaxaca es pionero en México en reconocer los usos y costumbres como forma de gobierno. Sin embargo, la participación política de las mujeres en este sistema es una asignatura pendiente. En este artículo se examina el acceso de ellas a puestos comunitarios y su experiencia en éstos a través de datos de una encuesta, dos talleres y tres entrevistas. Las que ocupan cargos son líderes, no tienen pareja y, aunque saben leer y escribir, están en la parte más baja de la pirámide comunitaria ejecutando las decisiones de otros; tienen sobrecarga de trabajo, su desempeño es juzgado con una doble vara y su reputación es puesta en duda por encontrarse en un medio predominantemente masculino. Para ellas, entre las satisfacciones derivadas de su labor están la convivencia con otras personas, conocer gente, aprender cosas nuevas y ganarse el respeto de la comunidad.

  1. Directional wave and temperature data from three buoys at San Nicolas Island, San Pedro and Dana Point, CA, January 2002 - June 2003 (NODC Accession 0001064)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Coastal Data Information Program (CDIP) is an extensive network for monitoring waves along the coastlines of the United States, with a strong emphasis on our...

  2. Maternally transferred anti-factor VIII IgG reduce the anti-factor VIII humoral immune response in factor VIII-deficient mice.

    Science.gov (United States)

    Meslier, Yann; André, Sébastien; Teyssandier, Maud; Kaveri, Srinivas V; Lacroix-Desmazes, Sébastien

    2010-12-01

    Replacement therapy with exogenous factor VIII (FVIII) to treat haemorrhages or used in prophylaxis induces inhibitory anti-FVIII immunoglobulin G (IgG) in some patients with haemophilia A. Therapeutic strategies to prevent the onset of the deleterious anti-FVIII immune response are still lacking. Maternal IgG is transferred to the offspring during fetal and neonatal life. While protecting the offspring from bacterial and viral infections, maternal IgG may alter the repertoires of T and B lymphocytes, and may impair vaccination in early infancy. Using haemophilic mice, we demonstrate that the transfer of maternal anti-FVIII IgG modulates the onset of anti-FVIII inhibitory IgG in early adulthood. The protective effect is reproduced upon reconstitution of naive mice with anti-FVIII IgG, suggesting that the reduced ability to mount an anti-FVIII immune response is the result of an interference between circulating anti-FVIII IgG and the administered FVIII rather than to a profound remodelling of lymphocyte repertoires occurring during the ontogeny of the immune system. © 2010 The Authors. Immunology © 2010 Blackwell Publishing Ltd.

  3. Acquired factor VIII inhibitor syndrome: A rare cause of hematuria

    Directory of Open Access Journals (Sweden)

    Muthuvel Seral Kannan

    2015-01-01

    Full Text Available A 50-year-old woman presented with gross hematuria for 1 month. Clinical examinations, laboratory investigations, ultrasound and contrast computed tomography were normal, except anemia. Cystoscopy revealed bloody efflux from the right side. Retrograde pyelogram showed filling defect in the renal pelvis and biopsy was inconclusive. Renal angiogram was normal. She developed ecchymosis on the right thigh and arm with elevated activated partial thromboplastin time. The partial thromboplastin time correction study and Bethesda study confirmed the presence of acquired factor VIII inhibitor (acquired hemophilia. With flexible ureterorenoscopy, the mass in the renal pelvis was removed and its histopathology revealed clotted blood. The patient was subsequently managed with steroids and Factor eight inhibitor bypass activity.

  4. A bispecific antibody mimicking factor VIII in hemophilia A therapy.

    Science.gov (United States)

    Nogami, Keiji

    2016-06-01

    Serious issues in current hemostatic treatment of hemophilia A are the requirement for frequent intravenous administrations of factor (F) VIII, FVIII inhibitor development, and hemostatic treatment for patients with this inhibitor. For the purpose of overcoming these challenges, the FVIIIa-substituting bispecific antibody against FIXa/FX (ACE910, INN emicizumab) was produced. Emicizumab demonstrated marked hemostatic effects on both ongoing and spontaneous joint bleeding in the acquired hemophilia A primate model. The clinical phase 1 study designed to assess the pharmacokinetics, pharmacodynamics and safety of emicizumab has been initiated. Severe emicizumab-related adverse events were minimal. The t1/2 was approximately 30 days, and bleeding events were significantly decreased by weekly subcutaneous administration in severe hemophilia A patients, independently of the presence of the inhibitor. Currently, the phase 1/2 extension study is ongoing. We anticipate that emicizumab will show the benefits of prophylactic efficacy with subcutaneous administration at a much lower frequency.

  5. Agnostic Stacking of Intergalactic Doublet Absorption: Measuring the Ne VIII Population

    Science.gov (United States)

    Frank, Stephan; Pieri, Matthew M.; Mathur, Smita; Danforth, Charles W.; Michael Shull, J.

    2018-02-01

    We present a blind search for doublet intergalactic metal absorption with a method dubbed `agnostic stacking'. Using a forward-modelling framework we combine this with direct detections in the literature to measure the overall metal population. We apply this novel approach to the search for Ne VIII absorption in a set of 26 high-quality COS spectra. We probe to an unprecedented low limit of log N>12.3 at 0.47≤z ≤1.34 over a pathlength Δz = 7.36. This method selects apparent absorption without requiring knowledge of its source. Stacking this mixed population dilutes doublet features in composite spectra in a deterministic manner, allowing us to measure the proportion corresponding to Ne VIII absorption. We stack potential Ne VIII absorption in two regimes: absorption too weak to be significant in direct line studies (12.3 13.7). We do not detect Ne VIII absorption in either regime. Combining our measurements with direct detections, we find that the Ne VIII population is reproduced with a power law column density distribution function with slope β = -1.86+0.18-0.26 and normalisation log f_{13.7} = -13.99+0.20-0.23, leading to an incidence rate of strong Ne VIII absorbers dn/dz =1.38+0.97-0.82. We infer a cosmic mass density for Ne VIII gas with 12.3 constituting 4% of the total baryonic mass.

  6. Defectos refractivos en estudiantes de la Escuela “Pedro D. Murillo” Refractive defects found in “Pedro D. Murillo” school students

    Directory of Open Access Journals (Sweden)

    Yaimir Estévez Miranda

    2011-12-01

    Full Text Available Objetivo: Caracterizar los defectos refractivos en niños de edad escolar en la escuela “Pedro Murillo” en el centro “Ciudad Escolar Libertad”. Métodos: Se realizó un estudio descriptivo, transversal con la finalidad de conocer los trastornos refractivos en niños de la primaria “Pedro Murillo” en el municipio Marianao, Ciudad de la Habana, en el periodo comprendido de septiembre 2010 a febrero de 2011. El universo estuvo formado por 422 estudiantes. Fueron 844 ojos a los que se le realizó un examen oftalmológico completo. Se distribuyeron según el defecto refractivo y su grado de severidad, edad, género y la frecuencia de la ambliopía. Resultados: El astigmatismo se presentó como la ametropía más frecuente para un 63,4 % y predominó el astigmatismo miópico compuesto. De las ametropías estudiadas prevaleció su forma leve (83 %. Se encontró una frecuencia de ambliopía de 3,7 % en los escolares. Conclusión: El comportamiento de los defectos refractivos observado, estuvo dentro de las cifras esperadas en relación a los reportes internacionales referidos al tema.Objectives: To characterize the refractive defects in children of school age in “Pedro Murillo” school in educational center Ciudad Libertad. Methods: A descriptive study and cross-sectional study was carried out to knowing the refractive disorders in elementary school children in “Pedro Murillo” school Marianao municipality, La Havana, in the from September 2010 to February, 2011. The universe was formed by 422 students. A complete ophthalmologic exam was performed on 844 eyes. They were distributed according to the refractive defect and their degree of severity, age, gender and the frequency of the amblyopia. Results: The astigmatism was the most frequent ametropia for 63.4 %, the compound myopic astigmatism prevailed. Of the studied ametropias their mild form prevailed for 83 %. The frequency of amblyopia was 3.7 % in students. Conclusions: The

  7. Pedro Ventura de Puga, último señor de la Casa de Fontefiz

    Directory of Open Access Journals (Sweden)

    Leirós de la Peña, Paz

    2007-12-01

    Full Text Available This paper is based on documentation from Casa de Fontefiz kept in the AHPOR. The documents cover the period from the sixteenth to nineteenth century and provide information about the patrimony of the house, its social position and the political activities of Pedro Ventura de Puga during the firts half of the nineteenth century. The first part is focused on the origin and evolution of patrimony, way of living, nobility abuses (including social and sexual aspects, and the difficulties to keep the social status. In the second part, Pedro Ventura plays the main role: his participation in the War of Independence and the building of the liberal state. He is a relevant character to undestand the adaptation of nobility to an age of political changes and social ad economical survivals. The defense of the constitution and his participation in the liberal regime is compatible with the maintenance of a economy based on the collection of taxes and nobility titles. Pedro Ventura is politically registered as a moderate liberalist.

    Este trabajo está basado en la documentación de la Casa de Fontefiz, conservada en al AHPOR. Los documentos abarcan desde el siglo XVI al XIX y nos aportan información sobre el patrimonio de la Casa, su posición social y las actividades políticas de Pedro Ventura de Puga en la primera mitad del siglo XIX. La primera parte se centra en el origen y evolución del patrimonio, modo de vida, abusos de la hidalguía en el plano social y sexual y las dificultades para mantener el stuatus social. La segunda parte tiene como protagonista a Pedro Ventura de Puga, su participación en la Guerra de la Independencia y en la construcción del estado liberal. Es una figura clave para entender la adaptación de la hidalguía a una época de cambios políticos y de pervivencias sociales y económicas. La defensa de la Constitución y la participación en el régimen liberal es compatible con el mantenimiento de una econocmía basada en

  8. Selected streambed sediment compounds and water toxicity results for Westside Creeks, San Antonio, Texas, 2014

    Science.gov (United States)

    Crow, Cassi L.; Wilson, Jennifer T.; Kunz, James L.

    2016-12-01

    IntroductionThe Alazán, Apache, Martínez, and San Pedro Creeks in San Antonio, Texas, are part of a network of urban tributaries to the San Antonio River, known locally as the Westside Creeks. The Westside Creeks flow through some of the oldest neighborhoods in San Antonio. The disruption of streambed sediment is anticipated during a planned restoration to improve and restore the environmental condition of 14 miles of channelized sections of the Westside Creeks in San Antonio. These construction activities can create the potential to reintroduce chemicals found in the sediments into the ecosystem where, depending on hydrologic and environmental conditions, they could become bioavailable and toxic to aquatic life. Elevated concentrations of sediment-associated contaminants often are measured in urban areas such as San Antonio, Tex. Contaminants found in sediment can affect the health of aquatic organisms that ingest sediment. The gradual accumulation of trace elements and organic compounds in aquatic organisms can cause various physiological issues and can ultimately result in death of the aquatic organisms; in addition, subsequent ingestion of aquatic organisms can transfer the accumulated contaminants upward through the food chain (a process called biomagnification).The U.S. Geological Survey, in cooperation with the San Antonio River Authority, collected sediment samples and water samples for toxicity testing from sites on the Westside Creeks as part of an initial characterization of selected contaminants in the study area. Samples were collected in January 2014 during base-flow conditions and again in May 2104 after a period of stormwater runoff (poststorm conditions). Sediment samples were analyzed for selected constituents, including trace elements and organic contaminants such as pesticides, brominated flame retardants, polychlorinated biphenyls (PCBs), and polycyclic aromatic hydrocarbons (PAHs). In addition, as an indicator of ecological health (and

  9. Type VIII collagen is elevated in diseases associated with angiogenesis and vascular remodeling

    DEFF Research Database (Denmark)

    Hansen, N. U. B.; Willumsen, N.; Bülow Sand, Jannie Marie

    2016-01-01

    Objectives Type VIII collagen is involved in angiogenesis and remodeling of arteries. We hypothesized that type VIII collagen was upregulated in diseases associated with vascular remodeling, e.g. pulmonary fibrosis and cancer. In this paper we present the development and validation of a competitive...... performance, and in relevant disease cohorts. The developed ELISA was applied for the assessment of type VIII collagen in serum from patients diagnosed with chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF) and various cancers. Results The C8-C ELISA was technically stable...

  10. Occurrence and concentrations of selected trace elements, halogenated organic compounds, and polycyclic aromatic hydrocarbons in streambed sediments and results of water-toxicity testing in Westside Creeks and the San Antonio River, San Antonio, Texas, 2014

    Science.gov (United States)

    Crow, Cassi L.; Wilson, Jennifer T.; Kunz, James L.

    2016-12-01

    Sediment samples and samples for water-toxicity testing were collected during 2014 from several streams in San Antonio, Texas, known locally as the Westside Creeks (Alazán, Apache, Martínez, and San Pedro Creeks) and from the San Antonio River. Samples were collected during base flow and after periods of stormwater runoff (poststorm conditions) to determine baseline sediment- and water-quality conditions. Streambed-sediment samples were analyzed for selected constituents, including trace elements and organic contaminants such as pesticides, polychlorinated biphenyls (PCBs), brominated flame retardants, and polycyclic aromatic hydrocarbons (PAHs). Potential risks of contaminants in sediment were evaluated by comparing concentrations of contaminants in sediment to two effects-based sediment-quality guidelines: (1) a lower level, called the threshold effect concentration, below which, harmful effects to benthic biota are not expected, and (2) a higher level, the probable effect concentration (PEC), above which harmful effects are expected to occur frequently. Samples for water-toxicity testing were collected from each stream to provide information about fish toxicity in the study area. The trace metal lead was detected at potentially toxic concentrations greater than the PEC in both the base-flow and poststorm samples collected at two sites sampled on San Pedro Creek. The PECs for the pesticides dichlorodiphenyldichloroethane, dichlorodiphenyldichloroethylene, dichlorodiphenyltrichloroethane, and chlordane were exceeded in some of the samples at the same two sites on San Pedro Creek. Brominated flame retardants and polybrominated diphenyl ether (PBDE) 85, 153, and 154 were found in all streambed-sediment samples. Federal Environmental Quality Guidelines established by Environment Canada for PBDE 99 and PBDE 100 were exceeded in all samples in which PBDE 99 was detected and in a majority of the samples in which PBDE 100 was detected; the greatest concentrations

  11. Performance: travestismos y política en las crónicas de Pedro Lemebel

    Directory of Open Access Journals (Sweden)

    Regina Vanesa Cellino

    2015-08-01

    Full Text Available En este trabajo se indagará sobre la relación que existe entre las crónicas urbanas de Pedro Lemebel, La esquina es mi corazón (1995 y Loco afán. Crónicas de sidario (1996, en el contexto de la posdictadura chilena, y su participación en las performances de Las Yeguas del Apocalipsis, a las que consideramos una articulación entre cuerpo, política y teatralidad. Este texto parte de las siguientes preguntas: ¿Qué afinidad/es hay entre las crónicas literarias de Lemebel y las performances de Las Yeguas del Apocalipsis? ¿Qué relación existe entre el cuerpo, la homosexualidad, el travestismo y la performance? ¿Cómo se manifiesta ese vínculo en las crónicas de Pedro Lemebel? 

  12. La melancolía en la obra de Pedro Gatell, cirujano y marino ilustrado

    Directory of Open Access Journals (Sweden)

    Peset, Jose Luis

    2014-06-01

    Full Text Available Melancholy is an emotion that has been in fashion from the Renaissance until now. During the Enlightenment, human reason was accompanied by strong feelings preparing for Romanticism. A prominent personality in this field was Pedro Gatell, naval surgeon and untiring writer. Throughout his novels and moral writings he shows the main developments coming from the experience of melancholy and its interpretation.La melancolía es una emoción de moda desde el Renacimiento hasta hoy, también en la Ilustración la razón se vio acompañada de fuertes sentimientos que anunciaban el Romanticismo. Personaje destacado en este terreno es Pedro Gatell, cirujano naval e infatigable escritor. En sus novelas y textos morales muestra las principales novedades que surgen en la vivencia melancólica y en su comprensión.

  13. Pedro Nuñez and the first printed treatise on twilight observation

    Science.gov (United States)

    Gadsden, M.

    Pedro Nuñez (the name is also written variously as Nunes, Nonius, Nonnius, and Nunnius) was born at Alcacer do Sol, Portugal, in 1502, and died in 1578. In that period and in that country, it was inevitable that his interests were in cosmography and navigation. His principal claim to fame is as author of the major treatise De Arte Atque Ratione Navigandi, which was published in 1546.

  14. Les assassins de l'inquisiteur Pedro Arbués

    OpenAIRE

    Combescure Thiry, Monique

    2005-01-01

    Le 15 septembre 1485 l'inquisiteur Pedro Arbués est égorgé dans la cathédrale de Saragosse. les plus importantes familles de judéo-convers de la ville sont impliquées dans le complot décrit dans l'un des manuscrit du Libro Verde de Aragon. Un siècle plus tard leurs descendants font encore partie de l'opposition aragonaise au pouvoir royal.

  15. Avaliação da sensibilidade da goiabeira 'Pedro Sato' ao ozônio

    Directory of Open Access Journals (Sweden)

    Regina Maria de Moraes

    2011-09-01

    Full Text Available O objetivo deste trabalho foi avaliar a sensibilidade da goiabeira 'Pedro Sato' ao ozônio (O3, em comparação à cultivar Paluma, descrita como sensível. Oito plantas de cada cultivar foram submetidas separadamente a ar filtrado e a ar filtrado + O3, cinco horas por dia, durante quatro dias. Foram avaliadas fotossíntese (Asat, injúrias foliares visíveis e concentração de antocianinas e taninos. Plantas das duas cultivares também foram expostas, durante três meses, a condições ambientais em local contaminado por O3, tendo-se avaliado fotossíntese, injúrias foliares e crescimento. Plantas fumigadas com O3 apresentaram redução de Asat e da atividade fotoquímica, além de manifestação de injúrias foliares. 'Paluma' apresentou maior redução de Asat, injúrias foliares mais severas e redução de taninos. Quando exposta ao ambiente contaminado, 'Paluma' apresentou trocas gasosas mais altas, mas apresentou redução de Asat 30 dias antes que 'Pedro Sato'. O crescimento não foi afetado em 'Pedro Sato', cujas injúrias foliares tiveram menor incidência, severidade e precocidade do que em 'Paluma'. A menor taxa de crescimento de 'Paluma' indica maior sensibilidade ao O3. Apesar de responder com menor intensidade ao estresse induzido pelo O3, a cultivar Pedro Sato não pode ser considerada tolerante, pois apresenta danos fotoquímicos, injúrias foliares e alterações nos conteúdos de metabólitos secundários quando exposta a esse poluente.

  16. Pedro de Valencia, Francisco de Gurmendi and the Plomos de Granada

    Directory of Open Access Journals (Sweden)

    Magnier, Grace

    2003-12-01

    Full Text Available The Inquisition in 1618 seized all the papers of Pedro de Valencia, renowned humanist, biblical scholar and chronicler of Philip III. The papers of other members of his circle were also confiscated. In this article I examine the two most important texts: Sobre el pergamino y láminas de Granada of Valencia and a Libelo Segundo of Francisco de Gurmendi, interpreter of Oriental languages for Philip III. The article is structured around Gurmendi's response to a memorial published in 1617 by Archbishop Pedro de Castro in defence of one of his translators. Gurmendi, working from his translation of the first two Lead Books, shows how these contain heretical ideas on the Trinity and how the memorialista has mistranslated many passages.

    En 1618 la Inquisición confiscó todos los papeles de Pedro de Valencia, humanista insigne, exegeta bíblico y cronista del reino y de las Indias de Felipe III. También confiscó los papeles de otros miembros de su círculo. En este artículo examino los dos textos más importantes: Sobre el pergamino y láminas de Granada de Valencia y un Libelo segundo de Francisco de Gurmendi, intérprete en lenguas orientales del rey. El artículo se centra en la respuesta de Gurmendi a un memorial del Arzobispo Pedro de Castro en el que se defiende a uno de sus traductores. Partiendo de su traducción de los dos primeros libros plúmbeos, Gurmendi muestra las herejías trinitarias que éstos contienen y cómo el memorialista ha traducido mal muchos pasajes.

  17. 78 FR 58878 - Safety Zone; San Diego Shark Fest Swim; San Diego Bay, San Diego, CA

    Science.gov (United States)

    2013-09-25

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; San Diego Shark Fest Swim; San Diego Bay... Diego Shark Fest Swim. This safety zone is necessary to provide for the safety of the participants, crew... this rule because the logistical details of the San Diego Shark Fest Swim were not finalized nor...

  18. PEDRo: A database for storing, searching and disseminating experimental proteomics data

    Directory of Open Access Journals (Sweden)

    Garwood Kevin

    2004-09-01

    Full Text Available Abstract Background Proteomics is rapidly evolving into a high-throughput technology, in which substantial and systematic studies are conducted on samples from a wide range of physiological, developmental, or pathological conditions. Reference maps from 2D gels are widely circulated. However, there is, as yet, no formally accepted standard representation to support the sharing of proteomics data, and little systematic dissemination of comprehensive proteomic data sets. Results This paper describes the design, implementation and use of a Proteome Experimental Data Repository (PEDRo, which makes comprehensive proteomics data sets available for browsing, searching and downloading. It is also serves to extend the debate on the level of detail at which proteomics data should be captured, the sorts of facilities that should be provided by proteome data management systems, and the techniques by which such facilities can be made available. Conclusions The PEDRo database provides access to a collection of comprehensive descriptions of experimental data sets in proteomics. Not only are these data sets interesting in and of themselves, they also provide a useful early validation of the PEDRo data model, which has served as a starting point for the ongoing standardisation activity through the Proteome Standards Initiative of the Human Proteome Organisation.

  19. Historia y globalización. VIII Conversaciones Internacionales de Historia [Reseña

    OpenAIRE

    Olábarri-Gortázar, I. (Ignacio)

    2013-01-01

    Reseña de Francisco Javier Caspistegui (ed.), Historia y globalización. VIII Conversaciones Internacionales de Historia. Universidad de Navarra. Pamplona, 7-9 de octubre de 2010, Pamplona, EUNSA, 2012. 318 pp. ISBN: 9788431328801.

  20. THE APPEARANCE OF THE INHIBITORS TO FACTOR VIII IN AN ELDER PATIENT WITH MILD HAEMOPHILIA A

    Directory of Open Access Journals (Sweden)

    Barbara Faganel

    2004-12-01

    Full Text Available Background. The inhibitors to F VIII are unusual in case of a mild haemophilia because the replacement therapy is seldom necessary. In case of severe trauma, when prolonged replacement therapy of F VIII is needed, the appearance of the inhibitors is more frequent. The mild form of the disease becomes a severe one and the haemorrhages are frequent.Patient and methods. In case of our patient with mild form of haemophilia, the inhibitors to F VIII developed after prolonged replacement therapy for treatement of subdural haemorrhage. In the article we describe recurrent haemorrhages and treatement of them with FEIBA and rF VIIa.Conclusions. Due to poor compliance of an elder patient we didn’t decide to treat the inhibitors for F VIII actively.

  1. A Cranial Trauma was the Cause of Death of Charles VIII of France (1470-1498).

    Science.gov (United States)

    Markatos, Konstantinos; Karamanou, Marianna; Arkoudi, Konstantina; Konstantinidi, Apostolia; Androutsos, Georgios

    2017-09-01

    This article summarizes the reign, life and death, of Charles VIII of France. Also we intend to investigate current views on his cause of death, contradictions and opinions of his biographers. Poisoning, disease, and injury are the possible causes of his death but, according to the literature, cranial trauma was the most probable cause of death of the King Charles VIII of France. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. PENGARUH KONSELING KELOMPOK TERHADAP KONFORMITAS SISWI KELAS VIII SMPIT BINA AMAL SEMARANG

    OpenAIRE

    sudyastuti sudyastuti; heru mugiarso

    2017-01-01

    This research was conducted based on the phenomenon that happens to grade VIII SMPIT Bina Amal Semarang which has the social conformity low. The purpose of this research is to proof  the influence of counseling service groups towards the conformity. The type of this research is experimental research. The research was conducted with seven times the grant of preferential treatment on grade VIII SMPIT Bina Amal Semarang, research subject with 8 students. The data collection method used is the ps...

  3. Type VIII collagen has a restricted distribution in specialized extracellular matrices

    OpenAIRE

    1988-01-01

    A pepsin-resistant triple helical domain (chain 50,000 Mr) of type VIII collagen was isolated from bovine corneal Descemet's membrane and used as an immunogen for the production of mAbs. An antibody was selected for biochemical and tissue immunofluorescence studies which reacted both with Descemet's membrane and with type VIII collagen 50,000-Mr polypeptides by competition ELISA and immunoblotting. This antibody exhibited no crossreactivity with collagen types I-VI by competition ELISA. The m...

  4. Implications of an updated ultraviolet background for the ionization mechanisms of intervening Ne VIII absorbers

    Science.gov (United States)

    Hussain, Tanvir; Khaire, Vikram; Srianand, Raghunathan; Muzahid, Sowgat; Pathak, Amit

    2017-04-01

    Ne VIII absorbers seen in QSO spectra are useful tracers of warm ionized gas, when collisional ionization is the dominant ionization process. While photoionization by the ultraviolet background (UVB) is a viable option, it tends to predict large line-of-sight thickness for the absorbing gas. Here, we study the implications of the recently updated UVB at low z to understand the ionization mechanisms of intervening Ne VIII absorbers. With the updated UVB, one typically needs higher density and metallicity to reproduce the observed ionic column densities under photoionization. Both reduce the inferred line-of-sight thicknesses of the absorbers. We find a critical density of ≥5 × 10-5 cm-3 above which the observed N({Ne VIII})/N({O VI}) can be reproduced by pure collisional processes. If the gas is of near solar metallicity (as measured for the low ions) then the cooling time-scales will be small (inferred low ion metallicity is near solar or supersolar. If we assume the Ne VIII phase to have similar metallicities then photoionization can reproduce the observed N({Ne VIII})/N({O VI}) without the line-of-sight thickness being unreasonably large and avoids cooling issues related to the collisional ionization at these metallicities. However, the indication of broad Lyα absorption in a couple of systems, if true, suggests that the Ne VIII phase is distinct from the low ion phase having much lower metallicity.

  5. Functional mapping of factor VIII C2 domain.

    Science.gov (United States)

    Pellequer, Jean-Luc; Chen, Shu-wen W; Saboulard, Didier; Delcourt, Marc; Négrier, Claude; Plantier, Jean-Luc

    2011-07-01

    The factor VIII (FVIII) is a cofactor of the coagulation cascade. The FVIII C2 domain is a critical domain that participates in the interactions with the von Willebrand factor and the phospholipidic surfaces. To assess the importance of each residue of this domain in the maintenance of the structure and the function of FVIII, a number (n=139) of mutants were generated by substituting the original residues, from Ser2173 to Gly2325, by an alanine. Mutants were built within a complete B domain-deleted FVIII and expressed in COS-1 cells. Mutant antigen levels and procoagulant activities were measured. Two in silico analyses, a sliding average procedure and an analysis of the mutation energy cost were conducted in parallel on the FVIII structure. Both results were in agreement with the functional data, and illustrated the benefit of using such strategies prior to targeting specific residues in the aim of generating active recombinant molecules. The functional assays identify the residues that are important to maintaining the structure of the C2 domain, mainly those forming β-sheet, and those that can afford substitution, establishing a detailed functional relation with the available crystallographic data. This study provided a comprehensive functional mapping of the FVIII C2 domain and discussed the implication of specific residues in respect to the maintenance in the activity and structure stability, the efficiency in secretion, the binding to phospholipids and the formation of epitope.

  6. piggyBac-mediated phenotypic correction of factor VIII deficiency

    Directory of Open Access Journals (Sweden)

    Janice M Staber

    2014-01-01

    Full Text Available Hemophilia A, caused by a deficiency in factor VIII (FVIII, is the most severe inherited bleeding disorder. Hemophilia A is an attractive gene therapy candidate because even small increases in FVIII levels will positively alter the phenotype. While several vectors are under investigation, gene addition from an integrated transgene offers the possibility of long term expression. We engineered the DNA transposon-based vector, piggyBac (PB, to carry a codon-optimized B-domain deleted human FVIII cDNA. Evaluation of gene transfer efficiency in FVIII null mice demonstrated that PB containing the FVIII cDNA, delivered via hydrodynamic injection to immunocompetent hemophilia mice, conferred persistent gene expression, attaining mean FVIII activity of approximately 60% with 3/19 developing inhibitors. In addition to efficacious expression, a goal of gene transfer-based therapies is to develop vectors with low toxicity. To assess endoplasmic reticulum stress in hepatocytes stably expressing the transgene, we evaluated levels of ER stress markers via qPCR and found no evidence of cell stress. To evaluate phenotypic correction, a tail clip assay performed at the end of the study revealed reduced blood loss. These data demonstrate that PB can be used to achieve sustained FVIII expression and long-term therapeutic benefit in a mouse model.

  7. 75 FR 55975 - Safety Zone; San Diego Harbor Shark Fest Swim; San Diego Bay, San Diego, CA

    Science.gov (United States)

    2010-09-15

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; San Diego Harbor Shark Fest Swim; San Diego... Shark Fest Swim, consisting of 600 swimmers swimming a predetermined course. The sponsor will provide 26...; San Diego Harbor Shark Fest Swim; San Diego Bay, San Diego, CA. (a) Location. The following area is a...

  8. Mercedes y privilegios para consolidar un mayorazgo indiano: de don Pedro Moctezuma Tlacahuepantzin a don Pedro Tesifón Moctezuma, primer conde de Moctezuma (1569-1639

    Directory of Open Access Journals (Sweden)

    Francisco Luis Jiménez Abollado

    2015-06-01

    Full Text Available Las adjudicaciones de mercedes y privilegios se convirtieron para los descendientes de Moctezuma II en una forma de sobrevivir a lo largo del período virreinal. Para ello esgrimieron razonamientos fundamentados en su ascendencia, la transmisión pacífica a la Corona hispánica de su patrimonio territorial, así como una presumible pobreza o necesidad. Este análisis se centrará en los sucesores del único hijo varón de Moctezuma que sobrevivió a la conquista castellana: don Pedro Moctezuma Tlacahuepantzin. Las adjudicaciones de mercedes, ayudas de costas y encomiendas vacas fueron continuas entre el último tercio del siglo xvi hasta el fin del período virreinal.

  9. Distribución geoquímica de elementos traza en los sulfuros pirita y cinabrio y en las intercalaciones pizarrosas de la capa de San Nicolás. Yacimiento de Almaden (Ciudad Real

    Directory of Open Access Journals (Sweden)

    Guijarro Galiano, J.

    1988-08-01

    Full Text Available The «Cuarcita del Criadero» of the Almadén ore Deposit is formed by two quartzitic zones, one upper and the other lower, separated by the denominated intermediate shales. The Upperr Quartzitic Zone comprises of the banging to the foot wall: the mineralized Iayer of «San Nicolás», the mineralized layer of «San Francisco» and the Intermediate Quartzites whereas the Lower Quartzitic Zone contains the mineralized layer of «San Pedro». In the present paper, we investigate, by means of plasma emission spectrometry by inductive coupling the distribution of certain trace elements, thirteen in pyrites, twelve in cinnabars and seventeen in the shaly strata of the mineralized layer of «San Nicolás», in order to establish the geochemical character of the pyrite, cinnabar and of the shaly strata just as the origin of the two sulphides.La «Cuarcita del Criadero» del yacimiento de Almadén está constituida por dos niveles cuarcíticos, superior e inferior, separados por las denominadas pizarras intermedias. La Cuarcita superior agrupa de techo a muro: la Capa de San Nicolás, la Capa de San Francisco y las Cuarcitas intermedias, mientras la Cuarcita inferior contiene la Capa de San Pedro. En el presente trabajo se estudian, mediante el análisis por espectrometria de emisión de plasma por acoplamiento inductivo, la distribución de ciertos elementos traza, trece en piritas, doce en cinabrios y diecisiete en interlaciones pizarrosas de la Capa de San Nicolás, para establecer el carácter geoquímico de la pirita, del cinabrio y del material pizarrooso intercalado así como la génesis de los dos sulfuros.

  10. Factor VIII and fibrinogen recovery in plasma after Theraflex methylene blue-treatment: effect of plasma source and treatment time.

    Science.gov (United States)

    Rapaille, André; Reichenberg, Stefan; Najdovski, Tome; Cellier, Nicolas; de Valensart, Nicolas; Deneys, Véronique

    2014-04-01

    The quality of fresh-frozen plasma is affected by different factors. Factor VIII is sensitive to blood component storage processes and storage as well as pathogen-reduction technologies. The level of fibrinogen in plasma is not affected by the collection processes but it is affected by preparation and pathogen-reduction technologies. The quality of plasma from whole blood and apheresis donations harvested at different times and treated with a pathogen-reduction technique, methylene blue/light, was investigated, considering, in particular, fibrinogen and factor VIII levels and recovery. The mean factor VIII level after methylene blue treatment exceeded 0.5 IU/mL in all series. Factor VIII recovery varied between 78% and 89% in different series. The recovery of factor VIII was dependent on plasma source as opposed to treatment time. The interaction between the two factors was statistically significant. Mean levels of fibrinogen after methylene blue/light treatment exceeded 200 mg/dL in all arms. The level of fibrinogen after treatment correlated strongly with the level before treatment. There was a negative correlation between fibrinogen level before treatment and recovery. Pearson's correlation coefficient between factor VIII recovery and fibrinogen recovery was 0.58. These results show a difference in recovery of factor VIII and fibrinogen correlated with plasma source. The recovery of both factor VIII and fibrinogen was higher in whole blood plasma than in apheresis plasma. Factor VIII and fibrinogen recovery did not appear to be correlated.

  11. Potentiation of thrombin generation in hemophilia A plasma by coagulation factor VIII and characterization of antibody-specific inhibition.

    Directory of Open Access Journals (Sweden)

    Bhavya S Doshi

    Full Text Available Development of inhibitory antibodies to coagulation factor VIII (fVIII is the primary obstacle to the treatment of hemophilia A in the developed world. This adverse reaction occurs in 20-30% of persons with severe hemophilia A treated with fVIII-replacement products and is characterized by the development of a humoral and neutralizing immune response to fVIII. Patients with inhibitory anti-fVIII antibodies are treated with bypassing agents including recombinant factor VIIa (rfVIIa. However, some patients display poor hemostatic response to bypass therapy and improved treatment options are needed. Recently, we demonstrated that fVIII inhibitors display widely variable kinetics of inhibition that correlate with their respective target epitopes. Thus, it was hypothesized that for antibodies that display slow rates of inhibition, supplementation of rfVIIa with fVIII would result in improved thrombin generation and be predictive of clinical responses to this novel treatment regimen. In order to test this hypothesis, 10 murine monoclonal antibodies (MAbs with non-overlapping epitopes spanning fVIII, differential inhibition titers, and inhibition kinetics were studied using a thrombin generation assay. Of the 3 MAbs with high inhibitory titers, only the one with fast and complete (classically defined as "type I" kinetics displayed significant inhibition of thrombin generation with no improvement upon supplementation of rfVIIa with fVIII. The other two MAbs that displayed incomplete (classically defined as "type II" inhibition did not suppress the potentiation of thrombin generation by fVIII. All antibodies that did not completely inhibit fVIII activity demonstrated potentiation of thrombin generation by the addition of fVIII as compared to rfVIIa alone. In conclusion, fVIII alone or in combination with rfVIIa corrects the thrombin generation defect produced by the majority of anti-fVIII MAbs better than single agent rfVIIa. Therefore, combined fVIII

  12. 75 FR 38412 - Safety Zone; San Diego POPS Fireworks, San Diego, CA

    Science.gov (United States)

    2010-07-02

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; San Diego POPS Fireworks, San Diego, CA... zone on the ] navigable waters of San Diego Bay in support of the San Diego POPS Fireworks. This safety... San Diego POPS Fireworks, which will include fireworks presentations conducted from a barge in San...

  13. Recombinant factor VIII in the management of hemophilia A: current use and future promise

    Directory of Open Access Journals (Sweden)

    Jerry S Powell

    2009-05-01

    Full Text Available Jerry S PowellDivision of Hematology and Oncology, University of California Davis Cancer Center, Sacramento, CA, USAAbstract: Hemophilia A is a rare inherited bleeding disorder due to mutation of the gene that encodes the coagulation protein factor VIII. Historically, prior to the availability of treatment with factor VIII preparations, most boys died from uncontrolled bleeding, either spontaneous bleeding or after injury, before reaching 20 years of age. One of the most impressive triumphs of modern medicine is that with current recombinant factor VIII replacement therapy, a boy born in the 21st century with severe hemophilia A can anticipate a normal life expectancy with essentially no permanent complications from bleeding. For severe hemophilia A, current optimal treatment should have two goals: first, to provide sufficient factor VIII to prevent spontaneous bleeding, and second, to provide sufficient factor VIII to have normal coagulation function after any trauma. However, the replacement therapy requires tremendous resources for effective use, and remains extraordinarily expensive. Thus there are opportunities for further advances in therapy for hemophilia A. Two major concerns continue to trouble current optimal treatment approaches: some patients will develop neutralizing antibodies during the first 50 infusions of therapeutic factor VIII, and second, to administer therapeutic factor VIII every other day in young boys often requires placement of a central venous access device, and such use carries the life-threatening risks of infection and thrombosis. Because of the effectiveness of current therapy, any new developments in treatment will require significant concerns for safety, both immediate and in the long term. A number of research groups seek to prolong the biological efficacy of infused recombinant factor VIII. Currently, one such promising development is in the advanced stages of clinical trial. The goals will be to improve

  14. BATUQUE, ARTE E EDUCAÇÃO NA COMUNIDADE QUILOMBOLA SÃO PEDRO DOS BOIS

    OpenAIRE

    Coelho, Clicia Tatiana Alberto; Diniz, Raimundo Erundino Santos

    2017-01-01

    Este artigo revela diferentes sentidos educacionais da manifestação sociocultural anunciada como Batuque existente na comunidade quilombola São Pedro dos Bois, localizada no Estado do Amapá/BR 156, a 75 km de distância da capital, Macapá. Entrelaça saberes das linguagens artísticas e suas visualidades, corporidades e simbologias inerentes a essa manifestação, compreendidos como discursos de firmamento da cultura quilombola no cotidiano escolar da comunidade. A metodologia utilizada anuncia-se...

  15. Culture and the city : Pedro Henríquez Ureña's New York city

    OpenAIRE

    Danny MÉNDEZ

    2011-01-01

    Pedro Henríquez Ureña’s memoir, written in 1909 while in México (but published in its entirety in 1989) may well be claimed as one of the first written accounts by a Dominican intellectual in the United States. In this paper I analyze the cultural implications of what it meant to be Dominican at the beginning of the 20th century for a non-white elite intellectual such as Henríquez Ureña in New York City. Although I view Henríquez Ureña’s memoir as a depiction of travel experiences of mo...

  16. Las cocinas del infierno. La visualidad de las mujeres en las calderas de Pedro Botero

    OpenAIRE

    Zuriaga Senent, Vicente Francesc

    2013-01-01

    Casi todas las religiones nos hablan del infierno como lugar en el que las almas son torturadas eternamente. El judaísmo lo llama Gehena, la mitología clásica Tártaro y Hades, las religiones paganas Inframundo, y la tradición cristiana castellana Las calderas de Pedro Botero. Los profetas del Antiguo Testamento narran con claridad los tormentos del infierno y Dante en La Divina Comedia nos lo relata con una visión particular. La literatura y el arte nos ofrecen abundancia de imáge...

  17. An analysis of Pedro de Ribadeneyra's Historia ecclesiastica del scisma de Inglaterra (1588)

    OpenAIRE

    Cid Morgade, Fátima

    2014-01-01

    Un aspecto central en el estudio de las relaciones hipano-inglesas en el siglo XVI es la reforma anglicana. Este hecho se narra por primera vez en español y desde una perspectiva católica en Historia ecclesiastica del scisma de Inglaterra (1558), escrita por el jesuita español Pedro de Ribadeneyra. Aunque esta obra tuvo una gran acogida en la época y durante siglos, la bibliografía actual sobre ella es muy escasa. En este estudio se analizarán la nueva estructura, fuentes adicionales, las abr...

  18. Information systems in health: a conversation with Pedro Urra González

    OpenAIRE

    Pedro Urra González

    2011-01-01

    En esta charla realizada en La Habana, en octubre de 2010, Pedro Urra González narra el contexto de surgimiento del Sistema Nacional de Información en Ciencias de la Salud de Cuba en la década del '60 y del proyecto Infomed, del cual fue fundador, a inicios de los años '90. Describe los fundamentos epistemológicos que sustentaron el desarrollo de Infomed como un proceso social y cultural, como espacio de integración de los esfuerzos del conocimiento, basado en una teoría del conocimiento orie...

  19. The franciscan fray Pedro Selleras (1555-1622 stayed out of the santoral

    Directory of Open Access Journals (Sweden)

    José Ignacio Gómez Zorraquino

    2017-07-01

    Full Text Available This article analyzes the various initiatives in the seventeenth and eighteenth centuries were taken to promote the beatification of franciscan Fray Pedro Selleras (1555-1622, who throughout his life story and after death was closely linked to a large area of Aragon. The excellence of the preacher Selleras were exposed by prominent prelates and writers of the Franciscan order (Gonzalez de Mendoza, French Urrutigoiti, Hebrera, Arbiol,..., in addition to other outstanding personalities (the Apaolaza prelates and courteous and Sanguesa,.... Despite all of this, our protagonist, in the process of the doctrinal purity, only surpassed the first test, which made him “venerable”.

  20. The model of television in Pedro Almodóvar. Cinema vs. Televisión

    OpenAIRE

    Gómez Gómez, Agustín

    2014-01-01

    In this paper we analyze the TV model presented by Pedro Almodóvar in his filmography. Of the eighteen movies, but three, all contain, one way or another, a reference to TV in a critical sense. Through the analysis of all his films, we observe the way in which TV appears and focus on four models or functions of the TV in his work. The first one has to do with the viewing mode, which we have named “domestic model”. A second function, which we will call “realistic”, is one which means that only...

  1. Cerebro y metáfora en la novela "Pedro Páramo", de Juan Rulfo

    Directory of Open Access Journals (Sweden)

    CECILIA EDILMA DÍAZ DÍAZ

    2010-01-01

    Full Text Available Se trata de un avance de investigación que aplica la teoría neurolingüística de Omar Parra Rozo para leer y comprender la metáfora en un texto literario. Se toma como objeto de estudio la novela "Pedro Páramo" de Juan Rulfo, específicamente los fragmentos que hablan acerca de la imagen compleja (religión-poder y muerte. El ejercicio de investigación alcanzó a establecer la relación que existe entre imagen- cerebro y metáfora, en el discurso de esta novela.

  2. A morte como elemento cultural mexicano em Pedro Páramo, de Juan Rulfo

    Directory of Open Access Journals (Sweden)

    Ana Paula Cantarelli

    2013-06-01

    Full Text Available Pedro Páramo (1955, de Juan Rulfo, desde sua publicação tem sido alvo de inúmeros estudos desenvolvidos por pesquisadores de diferentes áreas do conhecimento (história, sociologia, filosofia, etc.. Neste texto, buscou-se elaborar uma proposta de leitura a partir do reconhecimento da morte, símbolo nacional mexicano, como um elemento constituinte da estrutura narrativa desse romance, com a intenção de ampliar o campo de análises já delineado ao redor dessa obra.

  3. Presa de San Esteban

    Directory of Open Access Journals (Sweden)

    Equipo Editorial

    2017-06-01

    Full Text Available En el número 73 de esta revista se publicó un artículo, que trataba sobre los aprovechamientos hidroeléctricos de la cuenca del río Sil. En este trabajo se hace referencia, únicamente, a la importante presa de San Esteban, obra que, por so altura de salto, caudales disponibles y embalse, es la de mayor producción de las de la referida cuenca. Su proyección en planta e« circular, tipo gravedad, de 115 m de altura, y su embalse, de 213 millones de metros cúbicos.

  4. The F309S mutation increases factor VIII secretion in human cell line

    Directory of Open Access Journals (Sweden)

    Daianne Maciely Carvalho Fantacini

    2016-06-01

    Full Text Available ABSTRACT OBJECTIVES: The capacity of a human cell line to secrete recombinant factor VIII with a F309S point mutation was investigated, as was the effect of the addition of chemical chaperones (betaine and sodium-4-phenylbutyrate on the secretion of factor VIII. METHODS: This work used a vector with a F309S mutation in the A1 domain to investigate FVIII production in the HEK 293 human cell line. Factor VIII activity was measured by chromogenic assay. Furthermore, the effects of chemical drugs on the culture were evaluated. RESULTS: The addition of the F309S mutation to a previously described FVIII variant increased FVIII secretion by 4.5 fold. Moreover, the addition of betaine or sodium-4-phenylbutyrate increased the secretion rate of FVIIIΔB proteins in HEK 293 cells, but the same effect was not seen for FVIIIΔB-F309S indicating that all the recombinant protein produced had been efficiently secreted. CONCLUSION: Bioengineering factor VIII expressed in human cells may lead to an efficient production of recombinant factor VIII and contribute toward low-cost coagulation factor replacement therapy for hemophilia A. FVIII-F309S produced in human cells can be effective in vivo.

  5. Desenvolvimento de inibidores do fator VIII na hemofilia A Development of factor VIII inhibitors in hemophilia A

    Directory of Open Access Journals (Sweden)

    Daniel G. Chaves

    2009-01-01

    Full Text Available A hemofilia A é uma coagulopatia genética com herança recessiva ligada ao cromossomo X que afeta 1-2 a cada 10 mil indivíduos do sexo masculino nascidos vivos. Estes indivíduos têm baixas concentrações ou ausência do fator VIII (FVIII da coagulação no plasma e apresentam quadros hemorrágicos leves, moderados e graves, dependendo da atividade de FVIII circulante. Estes pacientes necessitam de constante reposição proteica e aproximadamente 30% deles desenvolvem aloanticorpos contra a proteína exógena. A síntese dos anticorpos anti-FVIII é iniciada quando o FVIII exógeno é endocitado por células apresentadoras de antígeno, degradado e apresentado às células T CD4+ na forma de peptídeos ligados a moléculas do complexo maior de histocompatibilidade (MHC de classe II. Alguns fatores de risco (paciente/tratamento podem ser relacionados ao desenvolvimento desta resposta imune. Neste contexto, as mutações no gene do FVIII e polimorfismos em genes envolvidos na resposta imune são candidatos moleculares como determinantes imunogenéticos na predisposição para o desenvolvimento de inibidores. Por não ser completamente entendido e controlado, o desenvolvimento desta resposta imune contra o FVIII constitui o maior problema decorrente do tratamento de indivíduos portadores de hemofilia A e faz-se necessária busca de opções que visem minimizar suas ações deletérias. Algumas alternativas de tratamento têm se mostrado eficazes no tratamento (anti-CD20, plasmaférese, concentrado de complexo protrombínico (PCCs, concentrado de complexo protrombínico ativado (APCCs, fator VII humano ativado, mas a retirada ou neutralização específica dos inibidores de FVIII ainda não foram alcançadas.Hemophilia A, which affects 1-2:10,000 live-born male neonates, is a genetic coagulopathy with recessive inheritance linked to the X chromosome. These individuals have low concentrations or no coagulation factor VIII (FVIII in the plasma

  6. Inventário analítico e registro de autoridade do fundo Colégio Pedro II

    OpenAIRE

    Silva, Elisabeth Monteiro da

    2009-01-01

    O trabalho compõe-se do inventário analítico do fundo Colégio Pedro II, bem como do registro de autoridade do produtor desse conjunto arquivístico, com o levantamento da legislação sobre educação e o colégio entre 1838 a 2009. O fundo Colégio Pedro II, localizado no NUDOM – Núcleo de Documentação e Memória do Colégio Pedro II – é formado por um conjunto de documentos administrativos nos quais foram registrados os atos praticados pela instituição desde a sua fundação em 1837 até meados da déca...

  7. Generation of an optimized lentiviral vector encoding a high-expression factor VIII transgene for gene therapy of hemophilia A.

    Science.gov (United States)

    Johnston, J M; Denning, G; Doering, C B; Spencer, H T

    2013-06-01

    We previously compared the expression of several human factor VIII (fVIII) transgene variants and demonstrated the superior expression properties of B domain-deleted porcine fVIII. Subsequently, a hybrid human/porcine fVIII molecule (HP-fVIII) comprising 91% human amino-acid sequence was engineered to maintain the high-expression characteristics of porcine fVIII. The bioengineered construct then was used effectively to treat knockout mice with hemophilia A. In the current study, we focused on optimizing self-inactivating (SIN) lentiviral vector systems by analyzing the efficacy of various lentiviral components in terms of virus production, transduction efficiency and transgene expression. Specifically, three parameters were evaluated: (1) the woodchuck hepatitis post-transcriptional regulatory element (WPRE), (2) HIV versus SIV viral vector systems and (3) various internal promoters. The inclusion of a WPRE sequence had negligible effects on viral production and HP-fVIII expression. HIV and SIV vectors were compared and found to be similar with respect to transduction efficiency in both K562s and HEK-293T cells. However, there was an enhanced expression of HP-fVIII by the SIV system, which was evident in both K562 and BHK-M cell lines. To further compare expression of HP-fVIII from an SIV-based lentiviral system, we constructed expression vectors containing the high expression transgene and a human elongation factor-1 alpha, cytomegalovirus (CMV) or phosphoglycerate kinase promoter. Expression was significantly greater from the CMV promoter, which also yielded therapeutic levels of HP-fVIII in hemophilia A mice. Based on these studies, an optimized vector contains the HP-fVIII transgene driven by a CMV internal promoter within a SIV-based lentiviral backbone lacking a WPRE.

  8. Los Angeles og San Francisco

    DEFF Research Database (Denmark)

    Ørstrup, Finn Rude

    1998-01-01

    Kompendium udarbejdet til en studierejse til Los Angeles og San Francisco april-maj 1998 Kunstakademiets Arkitektskole, Institut 3H......Kompendium udarbejdet til en studierejse til Los Angeles og San Francisco april-maj 1998 Kunstakademiets Arkitektskole, Institut 3H...

  9. Hemodialysis in a patient with severe hemophilia A and factor VIII inhibitor.

    Science.gov (United States)

    Gopalakrishnan, Natarajan; Usha, Thiruvengadam; Thopalan, Balasubramaniyan; Dhanapriya, Jeyachandran; Dineshkumar, Thanigachalam; Thirumalvalavan, Kaliaperumal; Sakthirajan, Ramanathan

    2016-10-01

    Hemophilia A is a hereditary X-linked recessive disease caused by mutations in the gene encoding factor VIII (FVIII), occurring in 1 out of 10,000 persons. Life expectancy and quality of life have dramatically improved recently in patients with hemophilia. Chronic kidney disease and need for renal replacement therapy in these patients are rare. The development of inhibitors to FVIII is the most serious complication of hemophilia and makes treatment of bleeds very challenging. We describe here a 28-year-old male patient with severe hemophilia A with presence of factor VIII inhibitor, who had end stage renal disease. Central venous access device was inserted along with infusion of factor eight inhibitor bypass activity before and after the procedure. He is currently on thrice weekly hemodialysis and doing well for 6 months without bleeding episodes. To our knowledge, hemophilia A with factor VIII inhibitor managed with hemodialysis has not been reported so far. © 2016 International Society for Hemodialysis.

  10. Identification of a Chemical Probe for Family VIII Bromodomains through Optimization of a Fragment Hit.

    Science.gov (United States)

    Gerstenberger, Brian S; Trzupek, John D; Tallant, Cynthia; Fedorov, Oleg; Filippakopoulos, Panagis; Brennan, Paul E; Fedele, Vita; Martin, Sarah; Picaud, Sarah; Rogers, Catherine; Parikh, Mihir; Taylor, Alexandria; Samas, Brian; O'Mahony, Alison; Berg, Ellen; Pallares, Gabriel; Torrey, Adam D; Treiber, Daniel K; Samardjiev, Ivan J; Nasipak, Brian T; Padilla-Benavides, Teresita; Wu, Qiong; Imbalzano, Anthony N; Nickerson, Jeffrey A; Bunnage, Mark E; Müller, Susanne; Knapp, Stefan; Owen, Dafydd R

    2016-05-26

    The acetyl post-translational modification of chromatin at selected histone lysine residues is interpreted by an acetyl-lysine specific interaction with bromodomain reader modules. Here we report the discovery of the potent, acetyl-lysine-competitive, and cell active inhibitor PFI-3 that binds to certain family VIII bromodomains while displaying significant, broader bromodomain family selectivity. The high specificity of PFI-3 for family VIII was achieved through a novel bromodomain binding mode of a phenolic headgroup that led to the unusual displacement of water molecules that are generally retained by most other bromodomain inhibitors reported to date. The medicinal chemistry program that led to PFI-3 from an initial fragment screening hit is described in detail, and additional analogues with differing family VIII bromodomain selectivity profiles are also reported. We also describe the full pharmacological characterization of PFI-3 as a chemical probe, along with phenotypic data on adipocyte and myoblast cell differentiation assays.

  11. CENTRAL, PEDro, PubMed, and EMBASE are the most comprehensive databases indexing randomized controlled trials of physical therapy interventions.

    Science.gov (United States)

    Michaleff, Zoe A; Costa, Leonardo O P; Moseley, Anne M; Maher, Christopher G; Elkins, Mark R; Herbert, Robert D; Sherrington, Catherine

    2011-02-01

    Many bibliographic databases index research studies evaluating the effects of health care interventions. One study has concluded that the Physiotherapy Evidence Database (PEDro) has the most complete indexing of reports of randomized controlled trials of physical therapy interventions, but the design of that study may have exaggerated estimates of the completeness of indexing by PEDro. The purpose of this study was to compare the completeness of indexing of reports of randomized controlled trials of physical therapy interventions by 8 bibliographic databases. This study was an audit of bibliographic databases. Prespecified criteria were used to identify 400 reports of randomized controlled trials from the reference lists of systematic reviews published in 2008 that evaluated physical therapy interventions. Eight databases (AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO, and PubMed) were searched for each trial report. The proportion of the 400 trial reports indexed by each database was calculated. The proportions of the 400 trial reports indexed by the databases were as follows: CENTRAL, 95%; PEDro, 92%; PubMed, 89%; EMBASE, 88%; CINAHL, 53%; AMED, 50%; Hooked on Evidence, 45%; and PsycINFO, 6%. Almost all of the trial reports (99%) were found in at least 1 database, and 88% were indexed by 4 or more databases. Four trial reports were uniquely indexed by a single database only (2 in CENTRAL and 1 each in PEDro and PubMed). The results are only applicable to searching for English-language published reports of randomized controlled trials evaluating physical therapy interventions. The 4 most comprehensive databases of trial reports evaluating physical therapy interventions were CENTRAL, PEDro, PubMed, and EMBASE. Clinicians seeking quick answers to clinical questions could search any of these databases knowing that all are reasonably comprehensive. PEDro, unlike the other 3 most complete databases, is specific to physical therapy, so studies not

  12. Carnaval de Sodoma de Pedro Antonio Valdez: retratos y vestiduras travestis

    Directory of Open Access Journals (Sweden)

    Julio Penenrey Navarro

    2014-12-01

    Full Text Available El travestimiento y las identidades queer son temas obviados y desentendidos por la crítica literaria que la novela Carnaval de Sodoma (2002, del escritor dominicano Pedro Antonio Valdez, ha merecido hasta el momento. A través del surgimiento de tres personajes travestidos de la obra —Tora, el Barón del cementerio-La Fortunata y Changsán- Princesa de Jade— examinaremos cómo la acción travesti desestabiliza el imaginario de naturalización y de complementariedad que el discurso normativo ha asignado a los géneros tradicionales (masculino/femenino, y repensaremos nociones como género y sexualidad, comúnmente establecidas por el pensamiento heterocentrado como entidades fijas e inmutables. Cross-dressing and queer identities constitute themes that are ignored and neglected by the literary critic that the novel Carnaval de Sodoma (2002, by Dominican writer Pedro Antonio Valdez has had until now. We will analyze three transvestite characters —Tora, the Baron of the graveyard-La Fortunata and Changsán-Princess of Jade— and examine how the transvestite action destabilize the naturalization and complementarization imaginary that the normative discourse has assigned to the traditional genders (masculine/femenine. We will rethink notions such as gender and sexuality, usually established by the heterocentered thought as fixe and immutable entities.

  13. OBLIQUE WAYS OF TRANSCENDENCE: ASPECTS OF IDEALISM IN AUGUSTO DOS ANJOS AND PEDRO KILKERRY

    Directory of Open Access Journals (Sweden)

    Fabiano Rodrigo da Silva Santos

    2014-12-01

    Full Text Available O ensaio analisa as manifestações do idealismo de orientação romântica na poesia de Augusto dos Anjos e Pedro Kilkerry, visando, por um lado, evidenciar os pontos de contato existente entre as obras dos dois poetas, e por outro, demonstrar que muitos dos procedimentos estéticos inovadores de que eles se servem nascem em resposta a urgências oriundas de uma concepção idealista da poesia. Augusto dos Anjos e Pedro Kilkerry manifestam o anseio por depreender junto à realidade fenomênica conexões com uma esfera suprassensível, que, embora assuma contornos distintos em cada um dos poetas, parece remeter a uma visão comum de um ideal poético transcendente à realidade concreta. Em busca desse objetivo, Augusto dos Anjos e Kilkerry recorrem a procedimentos que atualizam a dicção poética do sublime romântico; o primeiro vale-se de um repertório filosófico híbrido, que imprime um prosaísmo tenso e inovador em sua poesia, ao passo que o segundo opta pela representação indireta, por meio de uma linguagem evocativa e metonímica, que assinala o mistério do ideal transcendente, sem, contudo, decifrá-lo.

  14. Drevnerusskij pamflet na Mihaila VIII Paleologa v svete germenevtičeskogo analiza

    Directory of Open Access Journals (Sweden)

    Demincev Mihail

    2015-01-01

    Full Text Available In the article the perception of the image of Michael VIII Palaeologus by literate citizens of Tsardom of Russia is considered. The study is based on analysis of writings that date back to XVII century. The study focuses on identifying the symbols and latent ideas, that point to a semantic connection of the studied writings with The Old Testament, Apocalypse and some antique texts. In the end of the article the authjr makes a conclusion, that the perception of the image of Michael VIII Palaeologus in Tsardom of Russia was negative.

  15. Wavelengths and energy levels of Xe VII and Xe VIII obtained by collision-based spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Larsson, M.O. [Uppsala Univ. (Sweden). Dept. of Theoretical Physics; Gonzalez, A.M. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas (CIEMAT), Madrid (Spain). Inst. de Investigacion Basica; Hallin, R. [Uppsala Univ. (Sweden). Dept. of Theoretical Physics; Heijkenskjoeld, F. [Uppsala Univ. (Sweden). Dept. of Theoretical Physics; Hutton, R. [Lund Univ. (Sweden). Dept. of Physics; Langereis, A. [Uppsala Univ. (Sweden). Dept. of Theoretical Physics; Nystroem, B. [Lund Univ. (Sweden). Dept. of Physics; O`Sullivan, G. [University Coll., Dublin (Ireland). Dept. of Physics; Waennstroem, A. [Uppsala Univ. (Sweden). Dept. of Theoretical Physics

    1995-01-01

    The Xe VII and Xe VIII spectra have been investigated by collision-based spectroscopy. The radiation emitted following electron capture by 10q keV Xe{sup q+} ions (q = 6-8) impinging on a He (Ar) gas target has, with some exceptions, been recorded in the 350-8000 (1200-2500) A wavelength region. The xenon ions were provided by the Uppsala University ECR ion source. Many of the observed, previously unreported spectral lines have been identified. In total, nine new energy levels of Xe VII and Xe VIII have been established, of which two are tentative. The analysis was supported by Hartree-Fock calculations. (orig.).

  16. Acquired factor VIII inhibitor (acquired hemophilia A) presenting as spontaneous blood-filled scrotum.

    Science.gov (United States)

    Verma, Rajanshu; Noack, Jill; Vemuri, Radhakrishna; Loehrke, Mark E

    2011-05-01

    Acquired hemophilia A, also known as acquired factor VIII deficiency, is an exceedingly rare bleeding diathesis that does not require any personal or family history of bleeding or clotting disorder. Because treatment is available, misdiagnosing or completely missing this diagnosis can be life threatening for patients. Clinicians should be aware that acquired forms of hemophilia do exist and are associated with high morbidity and mortality in elderly adults. We present a case of a 74-year-old man who was diagnosed with acquired factor VIII inhibitor during an admission for community-acquired pneumonia.

  17. I prodromi della partita doppia in una corporazione monastica: la contabilità dell'Abbazia di San Pietro in Perugia dal 1461 al 1464

    Directory of Open Access Journals (Sweden)

    Alessandro Montrone

    2009-07-01

    Nuestro análisis se concentra en el Diario y el Mayor de los años 1461 a 1464, es decir, más de treinta años antes de la publicación del Tractatus De Computis et Scripturis de Luca Pacioli. Ello demuestra que en esa época la contabilidad por partida doble ya era aplicada en la Abadía de San Pedro. Aunque esta contabilidad no registra ni el capital ni los beneficios, sí permitía de cualquier modo una mejor administración y una mejor toma de decisiones.

  18. Conservação de goiabas ‘Pedro Sato’ minimamente processadas e irradiadas. = Conservation guavas ‘Pedro Sato’ minimally processed and irradiated.

    Directory of Open Access Journals (Sweden)

    André José de Campos

    2011-04-01

    Full Text Available O objetivo desse trabalho foi avaliar o efeito da irradiação gama associada à atmosfera modificada passiva na conservação refrigerada de goiabas ‘Pedro Sato’ minimamente processadas. Foram utilizadas goiabasprovenientes da região de Vista Alegre do Alto/São Paulo/Brasil. Após a colheita, as goiabas foram imediatamente transportadas ao Laboratório de Frutas e Hortaliças, pertencente ao Departamento de Gestão e Tecnologia Agroindustrial, da Faculdade de Ciências Agronômicas – UNESP – Campus de Botucatu/SP, onde foram mantidasa 10ºC e 90-95%UR em câmara frigorífica, por 12 dias. No laboratório, as goiabas foram selecionadas quanto ao tamanho e ausência de defeitos, visando uniformizar o lote e, posteriormente foram cortadas em fatias com 0,5 cm de espessura. Foi utilizado o delineamento inteiramente aleatorizado, com esquema fatorial 5 x 5, com três repetições. O primeiro fator consistiu dos seguintes efeitos: controle 1 (sem embalagem e sem irradiação; controle 2 (embalagem de poliestireno/PS + embalagem de polietileno de baixa densidade/PEBD e sem irradiação; tratamento 1 (PS+PEBD e 0,2kGy; tratamento 2 (PS+PEBD e 0,6kGy e tratamento 3 (PS+PEBD e 1,0kGy. O segundo fator consistiu dos períodos de avaliação, sendo: 0, 3, 6, 9 e 12 dias. As análises realizadas foram: firmeza, sólidos solúveis (SS, acidez titulável (AT, índice de maturação, pH, taxa de respiração. Concluiu-se que a menor dose de irradiação associada a atmosfera modificada passiva promoveu efeito positivo nas característicasfísico-químicas da goiaba ‘Pedro Sato’, proporcionando frutos com maior durabilidade e qualidade, devido a maior manutenção da firmeza de polpa e aos mais elevados valores de pH e sólidos solúveis obtidos. Em relação aos dias de armazenamento, não foi verificado efeito benéfico dos tratamentos no decorrer do armazenamento, principalmente devido à sensibilidade dos frutos submetidos à irradiação gama

  19. 46 CFR 54.01-2 - Adoption of division 1 of section VIII of the ASME Boiler and Pressure Vessel Code.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of division 1 of section VIII of the ASME... division 1 of section VIII of the ASME Boiler and Pressure Vessel Code. (a) Pressure vessels shall be designed, constructed, and inspected in accordance with section VIII of the ASME Boiler and Pressure Vessel...

  20. Variation in baseline factor VIII concentration in a retrospective cohort of mild/moderate hemophilia A patients carrying identical F8 mutations

    NARCIS (Netherlands)

    Loomans, J.I.; Velzen, A.S. van; Eckhardt, C.L.; Peters, M.; Makipernaa, A.; Holmstrom, M.; Brons, P.P.T.; Dors, N.; Haya, S.; Voorberg, J.; Bom, J.G. Van Der; Fijnvandraat, K.

    2017-01-01

    Essentials Factor VIII levels vary in mild and moderate hemophilia A (MHA) patients with the same mutation. We aimed to estimate the variation and determinants of factor VIII levels among MHA patients. Age and genotype explain 59% of the observed inter-individual variation in factor VIII levels.

  1. El mito prehispánico en las lunas y medias lunas de Pedro Páramo

    OpenAIRE

    Estrada Cárdenas, Alba

    2011-01-01

    This essay analyzes the myth of Cresent Moon in Pedro Páramo, and the connotations that it has related to the masculine, feminine, fertility and death. This to discover how two aspects of being Mexican are described in this novel.

  2. GABRIELA MISTRAL Y PEDRO AGUIRRE CERDA A TRAVÉS DE SU CORRESPONDENCIA PRIVADA (1919-1941

    Directory of Open Access Journals (Sweden)

    Matías Tagle Domínguez

    2002-01-01

    Full Text Available Gabriela Mistral and Pedro Aguirre Cerda made acquaintance of themselves in 1916. Since then, they maintained correspondence until 1941. The paper is based on a set of twenty-seven letters written by Gabriela Mistral to Pedro Aguirre Cerda from different places of the world, published in Mapocho journal in 1977. It also includes the Epistolario de Gabriela Mistral issued in the Epistolario de Pedro Aguirre Cerda (1938-1941 published by the Centro de Estudios Barros Arana. Finally, it incorporates a letter by Juana Aguirre de Aguirre to Mistral, dated in 1942. This is completed by different references that both of them made in their letters to other people. The paper reviews four aspects of the relation between Gabriela Mistral and Pedro Aguirre Cerda. The first topic is in regard to the poetess daily life aspects. A second question its related with Gabriela Mistral’s professional matters, specially the ones connected with her labor as an educator, as an international government employee and as a publicist of our country in other places of the world. The third issue is related to the poetess’s opinions concerning issues about Chilean politics. Finally, the fourth topic is in relation with subjects concerning Mistral’s private life and personal opinions.

  3. Un informe de Pedro de Ribera para Nueva España: el abastecimiento de agua a Guadalajara

    Directory of Open Access Journals (Sweden)

    Recio Mir, Álvaro

    2014-12-01

    Full Text Available The project proposed by the Franciscan architect Pedro Antonio de Buzeta to supply water to the New Spanish city of Guadalajara was sent to Madrid for review and supervision by the Council of the Indies. The Madrid architect Pedro de Ribera dealt with its technical aspects, and in 1735 he wrote an interesting critique of the plan. Among other questions, he defended the use of underground aqueducts, demonstrated his erudition and considered diverse improvements to Buzeta’s project.El proyecto que el arquitecto franciscano Pedro Antonio de Buzeta planteó para abastecer de agua a la ciudad novohispana de Guadalajara fue enviado a Madrid para que lo supervisase el consejo de Indias. De sus aspectos técnicos se ocupó el arquitecto madrileño Pedro de Ribera, que firmó una interesante crítica a la empresa en 1735. Entre otras cuestiones, hizo una defensa de los acueductos subterráneos, demostró su erudición y planteó diversas correcciones al proyecto de Buzeta.

  4. "Palabras de la Ciencia": Pedro Castera and Scientific Writing in Mexico's "Fin de Siècle"

    Science.gov (United States)

    del Pilar Blanco, María

    2014-01-01

    This essay explores the career of the understudied writer Pedro Castera (1846-1906), who is regarded as one of the first practitioners of science fiction in Mexico. A man of many talents, Castera is one of the most eccentric and eclectic figures in the intellectual life of fin-de-siècle Mexico City. His career took many turns: While during…

  5. Desain Pembelajaran Materi Luas Permukaan Prisma Menggunakan Pendekatan PMRI bagi Siswa Kelas VIII

    Directory of Open Access Journals (Sweden)

    Djuwita Trisnawati

    2015-08-01

    Full Text Available Penelitian ini bertujuan menghasilkan lintasan belajar untuk membantu siswa dalam pembelajaran luas permukaan prisma menggunakan kemasan produk di kelas VIII SMP. Penelitian ini berdasarkan PMRI yang dikaitkan dengan pembelajaran Kurikulum 2006/KTSP. Metode yang digunakan dalam penelitian ini adalah design research type validation study yang bertujuan untuk membuktikan teori-teori pembelajaran. Penelitian ini dilaksanakan di SMP Negeri 24 Palembang dengan melibatkan siswa kelas VIII yang berjumlah 31 siswa. Aktivitas-aktivitas pembelajaran yang dilakukan siswa meliputi: 1 memahami bentuk dan sifat prisma, 2 menemukan dan memahami konsep luas permukaan prisma, dan 3 menyelesaikan permasalahan dalam kehidupan sehari-hari yang berhubungan dengan luas permukaan prisma. Hasil dari penelitian ini menunjukkan bahwa melalui serangkaian aktivitas yang telah dilakukan membantu siswa dalam pembelajaran luas permukaan prisma.This research aimed to produce learning trajectory in learning surface area of prism using product packaging in class VIII. This study was based PMRI associated with learning curriculum 2006 / KTSP. The method used was design research of type validation study that aimed to prove the theories of learning. The research was conducted on 31 students of class VIII SMPN 24 Palembang. Students learning activities that were conducted including: (1 comprehending the shape and the characteristic of prism, (2 finding and comprehending the concept surface area of prism, and (3 solving the problems in daily life related to the surface area of prism. The results of this study indicate that a series of activities can help students in learning surface area of prism.

  6. A natural anatoxin, Amm VIII, induces neutralizing antibodies against the potent scorpion alpha-toxins.

    Science.gov (United States)

    Martin-Eauclaire, M-F; Alami, M; Giamarchi, A; Missimilli, V; Rosso, J-P; Bougis, P E

    2006-03-15

    In this study, we have used Amm VIII, a natural anatoxin from the scorpion Androctonus mauretanicus mauretanicus, to elicit specific polyclonal antibodies in rabbit. Using liquid-phase radioimmunoassay, we have studied its selectivity and its neutralizing activity both in vitro and in vivo for the most lethal scorpion alpha-toxins described, in particular the alpha-toxin of reference AaH II. We have shown that the anti-Amm VIII serum prevents the association of 125I-AaH II with its receptor and is able to remove 125I-AaH II already bound to its site (the half-life of the complex 125I-AaH II-receptor site was 12 min in the absence of anti-Amm VIII serum but decreased to only 2 min in the presence of anti-Amm VIII serum). In vivo, the serum also has a protective effect in mice: 42 LD50 of AaH II by millilitre are neutralized, measured by subcutaneous injection.

  7. Analysis of mutations in the entire coding sequence of the factor VIII gene

    Energy Technology Data Exchange (ETDEWEB)

    Bidichadani, S.I.; Lanyon, W.G.; Connor, J.M. [Glascow Univ. (United Kingdom)] [and others

    1994-09-01

    Hemophilia A is a common X-linked recessive disorder of bleeding caused by deleterious mutations in the gene for clotting factor VIII. The large size of the factor VIII gene, the high frequency of de novo mutations and its tissue-specific expression complicate the detection of mutations. We have used a combination of RT-PCR of ectopic factor VIII transcripts and genomic DNA-PCRs to amplify the entire essential sequence of the factor VIII gene. This is followed by chemical mismatch cleavage analysis and direct sequencing in order to facilitate a comprehensive search for mutations. We describe the characterization of nine potentially pathogenic mutations, six of which are novel. In each case, a correlation of the genotype with the observed phenotype is presented. In order to evaluate the pathogenicity of the five missense mutations detected, we have analyzed them for evolutionary sequence conservation and for their involvement of sequence motifs catalogued in the PROSITE database of protein sites and patterns.

  8. In vivo recovery and safety of human factor VIII product AAFACT in patients with haemophilia A

    NARCIS (Netherlands)

    Vossebeld, P. J. M.; Tissing, M. H.; van den Berg, H. M.; Leebeek, F. W. G.; de Goede-Bolder, A.; Novakova, I. R. O.; Gerrits, W. B. J.; Peters, M.; Koopman, M. M. W.; Faber, A.; Hiemstra, H.; Grob, P.; Strengers, P. F. W.

    2003-01-01

    AAFACT, a monoclonal purified, solvent/detergent treated human plasma-derived coagulation factor VIII concentrate obtained from plasma of voluntary, non-remunerated blood donors, is manufactured and marketed in the Netherlands by Sanquin Plasma Products since 1995. In a postmarketing surveillance

  9. Intercombination lines of AlVIII, AlIX, and AlX ions

    Science.gov (United States)

    Denne, B.; Hinnov, E.

    1984-06-01

    Several aluminum lines observed in the Princeton Large Torus tokamak discharges have been identified as intersystem transitions, establishing the energies of the Al VIII 2s2p35S, Al IX 2s2p24P, and Al X 2s2p3P terms. Some observations of isoelectronic transitions in scandium and titanium ions are also reported.

  10. Living in a physical world VIII. Gravity and life in water

    Indian Academy of Sciences (India)

    2006-07-31

    Jul 31, 2006 ... Home; Journals; Journal of Biosciences; Volume 31; Issue 3. Living in a physical world VIII. Gravity and life in water. Steven Vogel. Series Volume 31 Issue 3 September 2006 pp 309-322. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/jbsc/031/03/0309-0322 ...

  11. Idiopathic factor VIII inhibitor autoantibody in a man presented after accident.

    NARCIS (Netherlands)

    Mansouritorghabeh, H.; Lak, M.; Heerde, W.L. van

    2009-01-01

    Acquired hemophilia A is a rare but severe autoimmune bleeding disorder caused by autoantibodies against factor VIII activity and is a potentially life-threatening hemorrhagic disorder. The incidence of acquired hemophilia A has been estimated as 1.48 cases per million per year. The overall rate of

  12. Safety and Efficacy of BAY 94-9027, a Prolonged-Half-Life Factor VIII

    DEFF Research Database (Denmark)

    Reding, M T; Ng, H J; Poulsen, Lone Hvitfeldt

    2017-01-01

    BACKGROUND: BAY 94-9027 is a B-domain-deleted prolonged-half-life recombinant factor VIII (FVIII) conjugates in a site-specific manner with polyethylene glycol. OBJECTIVE: Assess efficacy and safety of BAY 94-9027 for prophylaxis and treatment of bleeds in patients with severe hemophilia A PATIEN...

  13. Factor VIII and von Willebrand factor co-delivery by endothelial cells

    NARCIS (Netherlands)

    Bouwens, E.A.M.

    2011-01-01

    A defect in coagulation factor VIII (FVIII) results in the inherited bleeding disorder hemophilia A. Current treatment of hemophilia A is hampered by the need of frequent administration of costly FVIII products. Therefore gene therapy is an attractive alternative for protein replacement to treat

  14. Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells

    NARCIS (Netherlands)

    van den Biggelaar, M.; Bouwens, E.A.M.; Kootstra, N.A.; Hebbel, R.P.; Voorberg, J.; Mertens, K.

    2009-01-01

    Background Gene therapy provides an attractive alternative for protein replacement therapy in hemophilia A patients. Recent studies have shown the potential benefit of directing factor (F)VIII gene delivery to cells that also express its natural carrier protein von Willebrand factor (VWF). In this

  15. Endocytic receptor for pro-coagulant factor VIII: relevance to inhibitor formation.

    Science.gov (United States)

    Navarrete, Ana-Maria; Dasgupta, Suryasarathi; Teyssandier, Maud; Repesse, Yohann; Delignat, Sandrine; André, Sébastien; Bayry, Jagadeesh; Kaveri, Srinivas V; Lacroix-Desmazes, Sébastien

    2010-12-01

    The immunogenicity of therapeutic factor VIII (FVIII) in patients with haemophilia A remains a critical issue in patient management. This review describes the immunological processes involved in the activation of the immune system against FVIII, with a particular focus on the role of endocytic receptors for the recognition of FVIII by antigen-presenting cells.

  16. Limited promiscuity of HLA-DRB1 presented peptides derived of blood coagulation factor VIII

    NARCIS (Netherlands)

    van Haren, Simon D.; Wroblewska, Aleksandra; Herczenik, Eszter; Kaijen, Paul H.; Ruminska, Aleksandra; ten Brinke, Anja; Meijer, Alexander B.; Voorberg, Jan

    2013-01-01

    The formation of inhibitory antibodies directed against coagulation factor VIII (FVIII) is a severe complication in the treatment of hemophilia A patients. The induction of anti-FVIII antibodies is a CD4(+) T cell-dependent process. Activation of FVIII-specific CD4(+) T cells is dependent on the

  17. Molecular characterization of a novel family VIII esterase from burkholderia multivorans UWC10

    CSIR Research Space (South Africa)

    Rashamuse, KJ

    2007-02-01

    Full Text Available was identified. Full-length sequencing of the DNA insert showed that it consisted of a single open reading frame (ORF1) encoding a predicted protein of 398 amino acids. ORF1 (termed EstBL) had a high protein sequence identity to family VIII esterases. The Est...

  18. Riparian Habitat - San Joaquin River

    Data.gov (United States)

    California Department of Resources — The immediate focus of this study is to identify, describe and map the extent and diversity of riparian habitats found along the main stem of the San Joaquin River,...

  19. Tras las huellas de Don Pedro Fermín de Vargas

    Directory of Open Access Journals (Sweden)

    Sergio Elías Ortíz

    1964-08-01

    Full Text Available Recibida en Madrid, a fines de 1790, una información sobre la virtud curativa de ciertas plantas del Virreynato de la Nueva Granada, cuestión que preocupó a los botánicos de la corte llamados a conjeturar sobre ellas, el Ministro de Estado, Marqués de Bajamar, se dirigió al Virrey Ezpeleta, en abril del año siguiente, en solicitud de una porción de la yerba Guaco, con la descripción hecha por don Pedro Fermín de Vargas, "y de la del Jaguo, u otro Obo de flor moradita, con expresión facultativa de la especie y virtud medicinal de otras plantas", cuyo envío debía confiarse al Director Botánico don Josef Celestino Mutis".

  20. The model of television in Pedro Almodóvar. Cinema vs. Televisión

    Directory of Open Access Journals (Sweden)

    Agustín GÓMEZ GÓMEZ

    2014-10-01

    Full Text Available In this paper we analyze the TV model presented by Pedro Almodóvar in his filmography. Of the eighteen movies, but three, all contain, one way or another, a reference to TV in a critical sense. Through the analysis of all his films, we observe the way in which TV appears and focus on four models or functions of the TV in his work. The first one has to do with the viewing mode, which we have named “domestic model”. A second function, which we will call “realistic”, is one which means that only what appears on screen exists, but Almodóvar desecrates reality through parody. A third model is a critique of so-called junk televisión. Finally, a fourth function is the presence of other films through the TV screen to establish an intertextual relationship with a narrative purpose.

  1. Culturalism and the "New" Poetry. A Poem by Pedro Gimferrer: "Cascabeles" from Arde el mar (1966

    Directory of Open Access Journals (Sweden)

    Guillermo Carnero

    1992-01-01

    Full Text Available The study deals with the group of Spanish poets commonly called the "novisimos" or "promocion de 1970," using as a base a poem by Pedro Gimferrer published in 1966. It studies the aesthetic break-through achieved by this generation, highlighting the concept of "culturalism" that critics used to define it twenty years ago. It examines the equivocal uses to which this concept can be put, and describes its correct meaning in the light of the aesthetic to which it refers. It then studies the mechanisms implicit in the writing of this non-confessional lyric poetry, centering it on two complementary procedures: the use of a historical persona that serves as an analogue ("personaje historico analogico", and that of another work of art that functions as an objectifying device ("obra de arte ajena objetivadora". It considers these in the light of two perspectives: the overcoming of neo-romantic rhetoric, and the participation of the reader.

  2. Imitative Tactics in Pedro de Padilla’s Églogas pastoriles: the Ovidian Mark

    Directory of Open Access Journals (Sweden)

    Soledad Pérez-Abadín Barro

    2017-11-01

    Full Text Available Pedro de Padilla’s Églogas pastoriles, bucolic book of virgilian extraction, diversify its configuration through the exercise of an eclectic imitatio, that canalizes the adoption of models foreign to pastoral tradition, amongst them Ovid, Boccaccio, Petrach, Sannazaro, Garcilaso and Fray Luis de León, incorporated with various imitative tactics. This paper shows the presence of two Ovid’s works, Remedia amoris and Fable of Narcissus (Metamorphoses, III, ls. 339-510, examples of heuristic imitatio, that allows to adapt the source to pastoral background, without disfiguring it. The Remedia amoris are object of a selective treatment, to be added as a marginal element to Silvano’ story. The Fable of Narcissus develops the ovidian myth, intermediated by the Alamanni’s Italian version, that also heads the Hernando de Acuña and Gregorio Silvestre’s recreations.

  3. Esbozo para una biografía del precursor Pedro Fermín Vargas

    Directory of Open Access Journals (Sweden)

    Guillermo Hernández de Alba

    1979-04-01

    Full Text Available Dos siglos corridos desde su nacimiento, más de uno y medio de la proclamación de la Independencia Nacional, han sido necesarios para que la memoria de Pedro Fermín de Vargas sea públicamente restituida a su patria, que al conocer y estudiar su vida extraordinaria lo celebrará entre los precursores de su libertad, lo admirará por la excelencia de su clara inteligencia y de su formación intelectual y le dará sitio de honor en los anales de su historia económica porque es capaz de proyectar, con arte de visionario, el estudio perfecto de la producción nacional y la distribución de su riqueza latente.

  4. El cine en el cine: Los abrazos rotos (Pedro Almodóvar, 2009

    Directory of Open Access Journals (Sweden)

    Pedro Poyato

    2012-10-01

    Full Text Available El cine en el cine, tema recurrente en la filmografía de Pedro Almodóvar, protagoniza también Los abrazos rotos, película que contiene en su interior otra titulada Chicas y maletas. Pero las imágenes de esta segunda película, trasunto de otra anterior del propio Almodóvar, Mujeres al borde un ataque de nervios, coexisten con las de un documental sobre su rodaje. El resultado es una proliferación de imágenes segundas que, incorporadas según una estructura en abismo, el filme va a conjugar de múltiples y variadas maneras. El presente trabajo trata de dar cuenta de la génesis, funcionamiento y declinación de estas imágenes segundas y de los sentidos que de ello emanan.

  5. VIII Olimpíada Brasileira de Astronomia e Astronáutica

    Science.gov (United States)

    Garcia Canalle, João Batista; Villas da Rocha, Jaime Fernando; Wuensche de Souza, Carlos Alexandre; Pereira Ortiz, Roberto; Aguilera, Nuricel Villalonga; Padilha, Maria De Fátima Catta Preta; Pessoa Filho, José Bezerra; Soares Rodrigues, Ivette Maria

    2007-07-01

    Neste trabalho apresentamos as motivações pelas quais organizamos, em conjunto, pela primeira vez, a Olimpíada Brasileira de Astronomia incluindo a Astronáutica, em colaboração com a Agência Espacial Brasileira. Esta ampliação contribuiu para atrair ainda mais alunos, professores, escolas e patrocinadores para participarem desta Olimpíada. Em 2005 participaram da VIII Olimpíada Brasileira de Astronomia e Astronáutica (VIII OBA) 187.726 alunos distribuídos por 3.229 escolas, pertencentes a todos os estados brasileiros, incluindo o Distrito Federal. O crescimento em número de alunos participantes foi 52,4% maior do que em 2004. Em abril de 2005 organizamos, em Itapecerica da Serra, SP, um curso para os 50 alunos previamente selecionados e participantes da VII OBA e ao final selecionamos, dentre eles, uma equipe de 5 alunos, os quais representaram o Brasil na X Olimpíada Internacional de Astronomia, na China, em outubro de 2005. Ganhamos, pela primeira vez, uma medalha de ouro naquele evento. Em Agosto de 2005, organizamos a VIII Escola de Agosto para 50 alunos e respectivos professores, em Águas de Lindóia, SP, juntamente com a XXXI reunião anual da Sociedade Astronômica Brasileira (SAB). Em novembro de 2005 realizamos a I Jornada Espacial, em São José dos Campos, com 22 alunos e 22 professores selecionados dentre os participantes que melhores resultados obtiveram nas questões de Astronáutica da VIII OBA. Neste trabalho detalhamos os resultados da VIII OBA bem como as ações subseqüentes.

  6. RELATIONSHIP OF INTEREST, LEARNING MOTIVATION AND ATTITUDE WITH RESULTS LEARNING CLASS VIII SMP STATE 13 MAKASSAR

    Directory of Open Access Journals (Sweden)

    Putri Athirah Azis

    2016-12-01

    Full Text Available The study aims at examining (1 the correlation of learning interest towards learning result of grade students, (2 the correlation of learning motivation towards learning result of grade students, (3 the correlation of students attitude towards learning result, (4 the correlationof interest, learning motivation, and attitude collaboratively towards learning result. The study is an ex post facto. The population of the study was grade VIII at SMPN 13 Makassar. Samples were 105 students taken by employing random sampling technique. Data were collected through questionnaire and documentation. Data were analyzed using regression test. The result of study reveal that (1 there is significant correlation (p<0,01 of interest towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,718 and its effectiveness contribution (R2 is 51,5%, (2 there is significant correlation (p<0,01 of motivation towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,775 and its effectiveness contribution (R2 is 60,1%, (3 there is significant correlation (p<0,01 of attitude towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,737 and its effectiveness contribution (R2 is 54,4%, (4 there is significant correlation (p<0,01 of interest, motivation and attitude collaboratively towards learning result of grade VIII students at SMPN 13 Makassar. Co-efficient correlation (r is 0,861 and its effectiveness contribution (R2 is 74,1%,

  7. La violencia y El otro lado del sueño de Pedro Luis Prados

    Directory of Open Access Journals (Sweden)

    Jaime Zambrano

    2013-08-01

    Full Text Available Es un análisis formal de los cuentos de El otro lado del sueño, de Pedro Luis Prados. El tema gira alrededor de la invasión de Panamá, por parte del ejército estadounidense, con la intención de deponer a Manuel Noriega en 1989. El estudio se centra en el tema de la violencia y en la forma como se incorpora en la ficción dándole un carácter peculiar, por el tratamiento histórico del tema que logra alejarse de la narración historicista. Aunque lo narrado tiene un carácter verosímil, la narrativa es una obra de ficción estéticamente lograda que descubre una nueva dimensión existencial y onírica del evento histórico. This is a formal analysis of short stories in El otro lado del sueño, by Pedro Luis Prados. The main theme is the invasion of Panama by the U.S. army, with the intention of deposing Manuel Noriega in 1989. The study focuses on the theme of violence and on how it is incorporated into the work of fiction, giving these short stories unique character, due to their treatment of history which distinguishes them from historic fiction. Although the narrations have a verisimilar essence, the stories become an esthetic work of fiction that exhibits a new oneiric and existential dimension of the historical events.

  8. Garcilaso de la Vega y Pedro Salinas: la voz a ti debida

    Directory of Open Access Journals (Sweden)

    Escarpín Gual, Montserrat

    2008-12-01

    Full Text Available This paper shows the relationship between two Spanish writers: Garcilaso de la Vega and Pedro Salinas; or better, the influence of the former over the latter. This influence may be noticed in different levels: the use of literary genres (eclogues, elegies or collections of verse, the conception of love, the use of myths and topics, the music of verse, etc. Some characteristics of Salinas’s style come clearly from Garcilaso (the intimacy, simplicity, orality, the dialogue, the use of the present tense and the first person, etc.. Our essay studies the influence of Garcilaso on the book Largo lamento, 1937?, written by Salinas at the same time as an essay about the renaissance poet —in addition of other unpublished works and his personal correspondence—, in order to show the presence of Garcilaso in his mind and all of his production.El artículo muestra la relación entre dos escritores españoles: Garcilaso de la Vega y Pedro Salinas; o mejor, la influencia del primero sobre el segundo. Esta puede observarse en diferentes niveles: el uso de géneros literarios (églogas, elegías o cancioneros, la concepción del amor, el uso de mitos y tópicos, la música del verso, etc. Algunas características del estilo de Salinas proceden claramente de Garcilaso (el intimismo, la sencillez, la oralidad, el empleo del diálogo, el presente verbal, la primera persona, etc.. Nuestro ensayo estudia la incidencia de Garcilaso en el libro Largo lamento, 1937?, que Salinas escribió en paralelo a un ensayo sobre el poeta renacentista —además de otros trabajos inéditos y su correspondencia personal—, para mostrar la presencia de Garcilaso en su pensamiento y en su producción.

  9. MANIFIESTOS Y UTOPÍAS, VIAJES Y VIDENCIA: UNA LECTURA MÍSTICA DE PEDRO PRADO

    Directory of Open Access Journals (Sweden)

    Patricio Lizama

    2012-11-01

    Full Text Available En este trabajo estudiamos textos de Pedro Prado desde una perspectiva mística, la cual es entendida por el autor con un fundamento religioso y otro ético-social. Por ello, sus personajes se elevan hacia niveles últimos de realidad, pero no se apartan de la "tierra de hombres" y se convierten en videntes que anhelan la belleza y la justicia. En "La barca", los personajes realizan un viaje horizontal y otro vertical para enfrentar el misterio; enAlsino, el viaje vertical es también para acercarse a la divinidad y el horizontal para enjuiciar el mundo rural chileno. La mediación entre el arriba y el abajo se representa con una embarcación que navega y vuela y con un hombre que camina y vuela, ambas figuras entendidas como alegorías del artista.This paper provides an analysis of the writings by Pedro Prado from a mystical perspective, an approach that the author himself understands as having religious as well as socio-ethical foundations. This is why Prado's characters rise towards ultimate levels of reality, but they never lose touch with the "land of men" to the point of turning into seers who yearn for beauty andjustice. In "La barca", the characters undertake a vertical ass well ass a horizontal journey in order to face the mystery. In Alsino, on the other hand, the vertical journey also serves to approach the divine, whereas the horizontal one is used to judge the Chilean rural world. The mediation between that which is above and what is below is represented by a ship that sails and flies, as well as by a man who walks and flies, both of which are to be seen as allegories of the artist.

  10. Datos para una biografía del jurista Pedro Murillo Velarde y Bravo

    Directory of Open Access Journals (Sweden)

    Luis Díaz de la Guardia y López

    2001-01-01

    Full Text Available En el presente artículo se pretende aportar una serie de coordenadas para fijar la vida y el pensamiento de Pedro Murillo Velarde y Bravo (Laujar 1696-Puerto de Santa María 1753. Hidalgo de familia de caballeros, sobrino de un Obispo de Pamplona, rompe en principio con el entorno familiar de búsqueda de ascenso social para dedicarse a la misión en Filipinas, llegando a ser procurador provincial de la Compañía en Filipinas ante la Corte de Madrid y Roma. Gran jurista, tiistoriador, geógrafo, poeta, político y orador. Por medio de documentos y obras del autor no sólo se desentraña la vida del jesuíta sino también su pensamiento frente a las Filipinas, la política o la religión.This article intends to contribute a series of coordinates to establish the life and thinking of Pedro Murillo Velarde y Bravo (Laujuar 1696-Puerto de Santa María 1753. Noble from a family of gentlemen and nephew of a Bishop of Pamplona, firstly breaks away from the family environment that seeks social promotion to dedicate himself to the mission in the Philippines, becoming the Society of Jesus'provincial representative in the Philippines before the Court of Madrid and Rome. Great jurist, historian, geographer, poet, politician and orator. Through the documents and works of the autor, not only is the life of the Jesuit unravelled but also his thinking on the Philippines politics and religión.

  11. Conservação de produto minimamente processado de goiabas 'Kumagai' e 'Pedro Sato' Conservation of 'Kumagai' and 'Pedro Sato' guavas minimally processed

    Directory of Open Access Journals (Sweden)

    Sarah Maria Athiê de Souza

    2009-09-01

    Full Text Available O processamento mínimo permite a obtenção de produtos com qualidade, frescor e conveniência para o consumidor. O objetivo deste trabalho foi determinar os efeitos de tipos de corte e de temperaturas de armazenamento na conservação de produto minimamente processado de goiabas 'Kumagai' e 'Pedro Sato', associando-se goiabas de polpa branca e de polpa vermelha num único produto, como forma de torná-lo mais atraente e nutritivo. Os frutos foram minimamente processados em rodelas e fatias, acondicionados em bandejas de poliestireno expandido, recobertas com filme de PVC 17µm e armazenadas a 5ºC e 15ºC, durante 9 dias. As análises foram realizadas a cada 3 dias quanto às suas características físicas e químicas (firmeza do mesocarpo e da região placentária, cor da casca e da região placentária e teores de sólidos solúveis, acidez titulável e ácido ascórbico e sensoriais (aparência. As temperaturas e os tipos de cortes não influenciaram nos conteúdos de ácido ascórbico, sólidos solúveis e acidez titulável. O corte tipo rodela manteve por mais tempo a firmeza do mesocarpo e da região placentária. A temperatura de 5ºC preservou a cor da casca, enquanto a de 15ºC e o corte tipo fatia implicaram maior escurecimento da polpa na região placentária. O produto minimamente processado mantido a 5ºC, bem como o corte em rodelas foram os preferidos pelos provadoresThe minimal processing allows obtaining products with high quality, freshness and great convenience to the consumer. In order to evaluate the use of white and red pulp guavas fruits together as a way to become more attractive and nutritional, the effect of types of cut and storage temperatures in guavas 'Kumagai' and 'Pedro Sato' minimally processed was evaluated. The fruits had been minimally processed in slice wheel and slices, packed in polystyrene trays, re-covered with PVC 17µm film and stored at 5 and 15ºC during 9 days. The analyses had been carried out

  12. Environmental assessment : Rodent control program : San Joaquin river levee : San Luis National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Lower San Joaquin Levee District (LSJLD) requires that six miles of levee situated along the San Joaquin River on San Luis National Wildlife Refuge (SLNWR) be...

  13. Characterization of the grafting copolymer EPDM-SAN; Caracterizacao do copolimero de enxertia EPDM-SAN

    Energy Technology Data Exchange (ETDEWEB)

    Turchette, Renato; Felisberti, Maria Isabel [Universidade Estadual de Campinas, SP (Brazil). Inst. de Quimica]. E-mail: turchete@iqm.unicamp.br

    2001-07-01

    This work aims the characterization of the grafting copolymer EPDM-SAN. This copolymer presents a fraction of free SAN chains, which was extracted by solubilization in chloroform followed of precipitation of the grafting copolymer EPDM-g-SAN in acetone. The EPDM-SAN and EPDM-g-SAN were characterized by {sup 13}C NMR, DSC, TGA and SEM. EPDM-SAN contain 23 wt% of free SAN and 77 wt% of EPDM-g-SAN. Both materials are heterogeneous and the thermal and thermo-oxidative degradation are independent of the composition. (author)

  14. Apología y censura: posibles autores de las crónicas favorables a Pedro I de Castilla

    Directory of Open Access Journals (Sweden)

    González de Fauve, María Estela

    2006-06-01

    Full Text Available

    The present historiography considers that from the times of Pedro I of Castile, favorable stories to this king must have existed which were destroyed after the triumph of the Trastámara dynasty, only interested in making sure a negative picure of the ";Cruel"; king was shown. In this work we have analyzed possible authors of the chronicles called ";true"; versus Ayala's ";false";, as well as the Relación de la vida del Rey D. Pedro attributed to Gracia Dei. The research allows us to conclude that various characteristics attributed to these characters, as well as the authorship of the chronicles they are adscripted to, are part of an advertising campaign started in the sixteenth century by one branch of the Castilla lineage that looks for the reaffirmation as legitimate descendants of Pedro I.



    La historiografía actual considera que, desde la época de Pedro I de Castilla, debieron existir obras favorables a este rey que fueron destruidas, tras el triunfo de la dinastía Trastámara, interesada en que sólo se difundiera una imagen negativa del rey ";Cruel";.En este trabajo analizamos los posibles autores de esas crónicas llamadas “verdaderas” frente a la “fingida” de Ayala, así como la Relación de la vida del Rey D.Pedro... atribuida a Gracia Dei . La investigación nos permite concluir que varias de las características atribuidas a estos personajes, así como la autoría de las crónicas que se les atribuyen, forman parte de una campaña propagandística iniciada en el siglo XVI por una rama del linaje de los Castilla que busca reafirmarse como descendencia legítima de Pedro I.

  15. Arhitektuur, võrgukultuur ja kuidas neist kasu saada = Architecture, networked cultures and how to make the most of them / Pedro Gadanho

    Index Scriptorium Estoniae

    Gadanho, Pedro

    2011-01-01

    Arhitekt Pedro Gadanho vaatleb olulist aspekti kõikvõimalike sündmuste puhul - vahetut suhtlemist. Vaatamata internetiajastul virtuaalruumi kolinud inimestevahelisele läbikäimisele on õigete inimestega kohtumine iga sündmuse oluline osa

  16. La construccion de "la loca" en dos novellas chilenas: El lugar sin limites de Jose Donoso y Tengo miedo torero de Pedro Lemebel

    National Research Council Canada - National Science Library

    Lopez Morales, Berta

    2011-01-01

    Este articulo intenta mostrar como se construye la identidad sexual y social del personaje 'la loca"en dos novelas chilenas, El lugar sin limites de Jose Donoso y Tengo miedo torero de Pedro Lemebel...

  17. 75 FR 26196 - Notice of Proposed New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII...

    Science.gov (United States)

    2010-05-11

    ..., (Title VIII, Pub. L. 108-447) AGENCY: National Forests in Mississippi, Forest Service, USDA. ACTION... 39269. SUPPLEMENTARY INFORMATION: The Federal Recreation Lands Enhancement Act (Title VII, Pub. L. 108...

  18. DAMPAK POSITIF DAN NEGATIF SOSIAL MEDIA TERHADAP PENDIDIKAN AKHLAK ANAK (Studi Kasus di SMP Negeri 2 Kelas VIII Banda Aceh)

    National Research Council Canada - National Science Library

    NISA KHAIRUNI

    2016-01-01

    The author examines the positive and negative effects of social media on the moral education of children in school SMPN 2 class VIII Banda Aceh, it is very interesting because of the many children who abuse social media...

  19. A novel approach in potential anticoagulants from peptides epitope 558-565 of A2 subunit of factor VIII.

    Science.gov (United States)

    Anastasopoulos, C; Sarigiannis, Y; Stavropoulos, G

    2013-04-01

    Factor VIII, a human blood plasma protein, plays an important role during the intrinsic pathway of blood coagulation cascade after its activation by thrombin. The activated form of FVIII acts as cofactor to the serine protease Factor IXa, in the conversion of the zymogen Factor X to the active enzyme Factor Xa. The Ser558-Gln565 region of the A2 subunit of Factor VIII has been shown to be crucial for FVIIIa-FIXa interaction. Based on this, a series of linear peptides, analogs of the 558-565 loop of the A2 subunit of the heavy chain of Factor VIII were synthesized using the acid labile 2-chlorotrityl chloride resin and biologically evaluated in vitro by measuring the chronic delay of activated partial thromboplastin time and the inhibition of Factor VIII activity, as potential anticoagulants.

  20. KEEFEKTIFAN PAIRED STORYTELLING DAN JIGSAW DALAM PENINGKATAN KOMPETENSI BERBICARA SISWA KELAS VIII SMP NEGERI 3 SLEMAN

    Directory of Open Access Journals (Sweden)

    Nurmiyati Nurmiyati

    2014-10-01

    Full Text Available Penelitian ini bertujuan untuk mengetahui: (1 apakah ada perbedaan keefektifan antara teknik paired storytelling, jigsaw, dan konvensional dalam meningkatkan kompetensi berbicara siswa, (2 teknik pembelajaran berbicara yang paling efektif antara ketiga teknik penelitian itu dalam meningkatkan kompetensi berbicara siswa kelas VIII SMP Negeri 3 Sleman. Penelitian ini menggunakan jenis penelitian eksperimen semu dengan nonequivalent control-group design. Hasil penelitian menunjukkan bahwa: (1 Ada perbedaan keefektifan antara teknik paired storytelling, jigsaw, and konvensional itu dalam meningkatkan kompetensi berbicara siswa dengan nilai F sebesar 3,532 dan signifikan dengan P < 0,05, yaitu sebesar 0,033, dan (2 teknik paired storytelling adalah teknik keterampilan berbicara yang paling efektif diantara ketiga teknik itu dalam meningkatkan kompetensi berbicara siswa kelas VIII SMP Negeri 3 Sleman dengan mean tertinggi sebesar 74,3492. Kata kunci: teknik paired storytelling, teknik jigsaw, teknik konvensional, kompetensi berbicara

  1. Genomic characterisation of the toxin Amm VIII from the scorpion Androctonus mauretanicus mauretanicus.

    Science.gov (United States)

    Alami, Meriem; Céard, Brigitte; Legros, Christian; Bougis, Pierre E; Martin-Eauclaire, Marie-France

    2006-04-01

    The genomic DNA sequence encoding the scorpion toxin Amm VIII was amplified from genomic DNA of the scorpion Androctonus mauretanicus mauretanicus from Morocco, subcloned and sequenced. An intron, with a high A+T content (73.5%), split a Gly codon at the end of the precursor signal peptide and the consensus GT/AG splice junction was identified in the Amm VIII gene. This intron of only 166 bp is the smallest intron described so far for a long-chain scorpion toxin gene. In addition, this study led to the identification of three new toxin-related genes. From the deduced amino acid sequences of the encoded precursor proteins, we found that the mature putative toxins were highly similar to the scorpion toxins Leiurus quinquestriatus quinquestriatus IV and Odonthobuthus doriae 1.

  2. Detection of Intracellular Factor VIII Protein in Peripheral Blood Mononuclear Cells by Flow Cytometry

    Directory of Open Access Journals (Sweden)

    Gouri Shankar Pandey

    2013-01-01

    Full Text Available Flow cytometry is widely used in cancer research for diagnosis, detection of minimal residual disease, as well as immune monitoring and profiling following immunotherapy. Detection of specific host proteins for diagnosis predominantly uses quantitative PCR and western blotting assays. In this study, we optimized a flow cytometry-based detection assay for Factor VIII protein in peripheral blood mononuclear cells (PBMCs. An indirect intracellular staining (ICS method was standardized using monoclonal antibodies to different domains of human Factor VIII protein. The FVIII protein expression level was estimated by calculating the mean and median fluorescence intensities (MFI values for each monoclonal antibody. ICS staining of transiently transfected cell lines supported the method's specificity. Intracellular FVIII protein expression was also detected by the monoclonal antibodies used in the study in PBMCs of five blood donors. In summary, our data suggest that intracellular FVIII detection in PBMCs of hemophilia A patients can be a rapid and reliable method to detect intracellular FVIII levels.

  3. Acquired hemophilia A caused by factor VIII inhibitors: report of a case.

    Science.gov (United States)

    Hosoya, Yoshinori; Matsumura, Miho; Madoiwa, Seiji; Zuiki, Toru; Matsumoto, Shiro; Nunomiya, Shin; Lefor, Alan; Sata, Naohiro; Yasuda, Yoshikazu

    2013-06-01

    We report a case of acquired hemophilia A (AHA) after esophageal resection. The patient was an 80-year-old woman whose preoperative activated partial-thromboplastin time (APTT) was well within the normal range, at 34.9 s. She underwent thoracic esophagectomy and gastric pull-up for superficial esophageal cancer (operative time, 315 min; intraoperative blood loss, 245 ml). Intrathoracic and subcutaneous bleeding occurred spontaneously on postoperative day (POD) 39. The APTT was prolonged, at 140 s, and factor VIII inhibitor was 36 Bethesda U/ml. Treatment with recombinant activated factor VII, prednisolone, and cyclophosphamide resulted in remission within 2 months. This case supports an association between surgery and the triggering of factor VIII inhibitors. The diagnosis of AHA requires clinical acumen and must be considered in any patient with bleeding and a prolonged APTT.

  4. Treatment of radiation osteomyelitis of the mandible in a patient with acquired factor VIII inhibitor

    Energy Technology Data Exchange (ETDEWEB)

    Arimoto, Takamasa; Kishimoto, Hiromitsu; Matsumoto, Suwako; Kawanaka, Masao; Urabe, Masahiro; Yoshioka, Wataru [Hyogo Coll. of Medicine, Nishinomiya (Japan)

    1996-07-01

    A case of radiation osteomyelitis of mandible in a 56-year-old man with acquired factor VIII inhibitor is presented. He had undergone radiation therapy for malignant lymphoma of the tonsilar region seven years earlier, and also had received steroids to treat acquired factor VIII inhibitor for a year. On initial examination, he was given a diagnosis of phlegmon of the cheek caused by pericoronitis of the left lower wisdom tooth. To prevent the recurrence of inflammation, the wisdom tooth was extracted carefully, but radiation osteomyelitis occurred in association with a pathological fracture of the condylar head. After mini-pulse therapy with methylpredonisolone, segmental mandibulectomy and reconstruction with a titanium metal plate were performed. The postoperative course was satisfactory with no complications such as bleeding or infection. (author)

  5. Pengembangan Modul Matematika Untuk Pembelajaran Berbasis Masalah (Problem Based Learning) Pada Materi Pokok Persamaan Garis Lurus Kelas VIII SMP

    OpenAIRE

    Khayati, Fitrotul; Sujadi, Imam; Sari Saputro, Dewi Retno

    2016-01-01

    Absrtact:The objectives of this research were to investigate: (1) how to develop of Mathematics module development for problem-based learning on the topic of discussion of Linear Equation of Straight Line for Grade VIII of Junior Secondary School; and (2) the effectiveness of result of Mathematics module development for problem-based learning on the topic of discussion of Linear Equation of Straight Line for Grade VIII of Junior Secondary School. This research consisted of two phases. The fi...

  6. Reflexiones sobre el pensamiento utópico de Pedro Henríquez Ureña

    Directory of Open Access Journals (Sweden)

    Avome Mba Giséle

    2008-07-01

    Full Text Available Resumen:Pretendemos en este trabajo analizar el planteamiento de la utopía en la obra de Pedro Henríquez Ureña: LaUtopía de América. El pensamiento social latinoamericano se produce con la intención de reflexionar sobre la identificaciónde los destinos de las sociedades latinoamericanas.Palabras claves:Utopía; positivismo; individual; colectivo; Identidad Americana Abstract:We aim in this essay to analyze the approach of utopia in the book of Pedro Henriquez Urena: The Utopia of America.The Latin American social ideas occurs with the intent to think on the identification of the destinations of LatinAmerican societies.Key Words: Utopia, Imagination, Brotherhood, Justice, Race

  7. Influence of the type of factor VIII concentrate on the incidence of factor VIII inhibitors in previously untreated patients with severe hemophilia A.

    Science.gov (United States)

    Goudemand, Jenny; Rothschild, Chantal; Demiguel, Virginie; Vinciguerrat, Christine; Lambert, Thierry; Chambost, Hervé; Borel-Derlon, Annie; Claeyssens, Ségolène; Laurian, Yves; Calvez, Thierry

    2006-01-01

    Inhibitor development is the major treatment complication in children with severe hemophilia A. It is not clear whether the risk of inhibitors is higher with recombinant factor VIII or with plasma-derived factor VIII. We used multivariate analysis to compare 2 cohorts of previously untreated patients (PUPs) with severe hemophilia A: 62 patients treated with the same brand of high-purity plasma-derived FVIII (pFVIII) containing von Willebrand factor (VWF) and 86 patients treated with full-length recombinant FVIII (rFVIII). In addition to the usual end points (all inhibitors, high inhibitors), we also examined a third end point (high inhibitors and/or immune tolerance induction). The risk of inhibitor development was higher in patients treated with rFVIII than in patients treated with pFVIII, regardless of other risk factors (F8 genotype; nonwhite origin; history of inhibitors in patients with a family history of hemophilia; age at first FVIII infusion). The adjusted relative risk (RRa) for inhibitor development with rFVIII versus pFVIII was 2.4 (all inhibitors), 2.6 (high inhibitors), and 3.2 (high inhibitors and/or immune tolerance induction), respectively, depending on the end point (above). The pathophysiology of this large effect must be understood in order to improve the characteristics of recombinant products and to reduce the incidence of inhibitors to FVIII.

  8. Pedro Peláez, líder del clero filipino

    Directory of Open Access Journals (Sweden)

    Blanco Andrés, Roberto

    2011-12-01

    Full Text Available This article provides new information on the creole Filipino, Fr. Pedro Pablo Peláez, who, together with Fr. José Burgos, was the most outstanding clergyman in the nineteenth-century Philippines. It discusses Father Peláez’s previously unknown activities in the cabildo of the Manila Cathedral, where he was its most distinguished member. It analyzes his reformist ideas, and explains his work and strategy to defend the Filipino secular clergy, whose rights were being violated by the royal orders of 1848 and 1861. Against the reactionary religious orders, Peláez had a detailed modus operandi to defend the legitimacy of native priests’ control of parishes. Although his activities were cut short by his unexpected death in the earthquake of June 1863, Peláez served as an inspiration to be emulated.

    En este trabajo se intentan aportar algunas claves y datos inéditos sobre la biografía del presbítero criollo filipino Pedro Pablo Peláez, que es, junto con el P. José Burgos, el eclesiástico más destacado de la iglesia de Filipinas del siglo XIX. El trabajo aborda la totalmente desconocida actividad del P. Peláez en el cabildo de la catedral de Manila, donde acabaría siendo con el tiempo su hombre más insigne. Igualmente se analiza el espíritu e ideario reformista de Peláez y sus trabajos y estrategia para defender al clero secular filipino, cuyos derechos estaban siendo vulnerados por una serie de Reales Órdenes (1848 ó 1861 y la actitud reaccionaria de un sector de las órdenes religiosas. Peláez supo articular un modus operandi minucioso y muy efectivo en torno a la legitimidad de los curas filipinos en la dirección de las parroquias del país. Aunque sus actividades cesaron con su inesperada muerte en el terremoto de junio de 1863, Peláez se convirtió en una inspiración y un modelo a seguir.

  9. El plano secuencia: Pedro Costa y la trilogía de Fontainhas

    Directory of Open Access Journals (Sweden)

    Vieguer, Marcelo

    2012-01-01

    Full Text Available [es] Desde la aparición del plano secuencia en forma expresiva con Citizen Kane, tal recurso se convirtió en sinónimo de modernidad cinematográfica. Ni tanto ni tan poco, el uso del plano secuencia, generalmente visible, se lo comprendió como maniera formal y toque de virtuosismo. Con el director portugués Pedro Costa, es posible entender de qué manera la crítica y teoría fílmica sobredimensionan criterios esté-ticos ante lo políticamente correcto. Con la realización de la trilogía sobre Fontainhas, Costa se ha convertido en uno de los directores excéntricos más relevantes de los últimos quince años. El recurrente uso del plano secuencia fílmico y su persuasión política a través de las imágenes discurre sobre las condiciones de producción y recepción del cine contemporáneo, poniendo énfasis en llevar a la luz del día del escenario audiovisual los sectores excluidos de su Lisboa, iniciando un periplo que comienza en Fontainhas. [en] Since the sequence shot expressively appeared with Citizen Kane, this resource became synonymous with cinematic modernity. Neither that much nor that little, the use of the sequence shot, usually visible, is understood as formal manieraand a touch of virtuosity. With the Portuguese director Pedro Costa it is possible to understand how film criticism and theory favor aesthetic criteria rather than what is politically correct. With the production of the trilogy about Fontainhas, Costa has become one of the most important marginal directors in the last fifteen years. The recurrent use of the film sequence shot and his political persuasion through images run on the conditions of production and reception of contemporary cinema, with a clear intention to bring into the light of audiovisual stage the excluded areas of Lisbon, starting a long journey that begins in Fontainhas.

  10. Radiação gama e atmosfera modificada passiva na qualidade de goiabas 'Pedro Sato'

    Directory of Open Access Journals (Sweden)

    André José de Campos

    2011-10-01

    Full Text Available O objetivo deste trabalho foi avaliar o efeito da irradiação gama associada à atmosfera modificada passiva na qualidade pós-colheita de goiabas 'Pedro Sato', verificando suas características físico-químicas. Foram utilizadas goiabas provenientes da região de Vista Alegre do Alto-SP,Brasil. Após a colheita, as goiabas foram imediatamente transportadas ao Laboratório de Frutas e Hortaliças, pertencente ao Departamento de Gestão e Tecnologia Agroindustrial, da Faculdade de Ciências Agronômicas - UNESP - Câmpus de Botucatu-SP, onde foram armazenadas a 10ºC e 90-95%UR, em câmara frigorífica, por 28 dias. Os tratamentos foram: controle 1 (sem embalagem e sem irradiação; controle 2 (embalagem de poliestireno (PS + polietileno de baixa densidade (PEBD e sem irradiação; tratamento 1 (PS+PEBD e 0,2kGy; tratamento 2 (PS+PEBD e 0,6kGy, e tratamento 3 (PS+PEBD e 1,0kGy. As análises realizadas foram: firmeza, sólidos solúveis (SS, acidez titulável (AT e índice de maturação. Foi utilizado o delineamento inteiramente casualizado, com esquema fatorial 5 x 5 (tratamento x tempo. Concluiu-se que as altas doses de irradiação promoveram efeito negativo nas características físico-químicas da goiaba 'Pedro Sato', e que apenas a menor dose utilizada (0,2kGy associada à atmosfera modificada conservou frutos com maior qualidade e aceitabilidade, indicado por maiores índice de maturação e teor de sólidos solúveis obtidos.

  11. Contrapuntos hagiográficos sobre el Venerable Fr. Pedro de Urraca (Jadraque 1583 - Lima 1657

    Directory of Open Access Journals (Sweden)

    Rene Millar

    2008-01-01

    Full Text Available El artículo analiza cuatro hagiografías, dos de ellas inéditas, que se escribieron en diferentes épocas sobre el Venerable Fr. Pedro de Urraca, que nació en Jadraque, España, en 1583 y murió en Lima, en fama de santidad, en 1657. Se estudia el contenido y objetivo de las obras con el fin de apreciar las diferencias que presentan y las variaciones en el tiempo que, desde la perspectiva de la mentalidad religiosa, reflejan. Pero también se examina la relación que tuvieron con el proceso de beatificación del protagonista, para tratar de entender la influencia que ejercieron en dicho proceso. Al mismo tiempo, se pretende ver la manera como este contribuyó a marcar las características y orientación de las obras. En ese contexto, postulamos que la primera de las hagiografías, la que se escribió un mes después de la muerte del Siervo de Dios y que aún permanece inédita, tuvo una gran influencia en la orientación de la causa de beatificación y hasta cierto punto marcó su trayectoria y también influyó, directa o indirectamente, en las hagiografías que se escribieron con posterioridad.This article analyzes four hagiographies-two of them unpublished-that were written in different periods about the Venerable Friar Pedro de Urraca, who was born in Jadraque, Spain, in 1583, and died in Lima, renowned for his sanctity, in 1657. The author studies the content and objective of these literary works with the purpose of appreciating the differences and the variations over time that they present and reflect, from the perspective of religious mentality. However, the author also examines the relation they had with the process of beatification of the protagonist, in order to try to understand the influence that they exercised on said process. At the same time, the author attempts to see the way in which this process left its traces on the characteristics and direction of the works. In this context, the author proposes that the first of the

  12. IMPLEMENTASI PENDEKATAN KONFLIK KOGNITIF DALAM PEMBELAJARAN FISIKA UNTUK MENUMBUHKAN KEMAMPUAN BERPIKIR KRITIS SISWA SMP KELAS VIII

    OpenAIRE

    A. Setyowati; B. Subali; Mosik -

    2012-01-01

    Tujuan dari penelitian ini adalah untuk mengetahui pengaruh implementasi pendekatan konflik kognitif dalam pembelajaran fisikapokok bahasan tekanan pada siswa kelas VIII terhadap kemampuan berpikir kritis, pemahaman konsep dan hasil belajar kognitifsiswa. Penelitian ini merupakan penelitian eksperimen. Setelah dilakukan pengambilan sampel secara random sampling,diperoleh kelas VIIIB sebagai kelas eksperimen dan kelas VIIIC sebagai kelas kontrol. Dari analisis uji rata-rata dua pihak atau uji ...

  13. Construction of a mouse model of factor VIII deficiency by gene targeting

    Energy Technology Data Exchange (ETDEWEB)

    Bi, L.; Lawler, A.; Gearhart, J. [Univ. of Pennsylvania School of Medicine, Philadelphia, PA (United States)] [and others

    1994-09-01

    To develop a small animal model of hemophilia A for gene therapy experiments, we set out to construct a mouse model for factor VIII deficiency by gene targeting. First, we screened a mouse liver cDNA library using a human FVIII cDNA probe. We cloned a 2.6 Kb partial mouse factor VIII cDNA which extends from 800 base pairs of the 3{prime} end of exon 14 to the 5{prime} end of exon 26. A mouse genomic library made from strain 129 was then screened to obtain genomic fragments covering the exons desired for homologous recombination. Two genomic clones were obtained, and one covering exon 15 through 22 was used for gene targeting. To make gene targeting constructs, a 5.8 Kb genomic DNA fragment covering exons 15 to 19 of the mouse FVIII gene was subcloned, and the neo expression cassette was inserted into exons 16 and 17 separately by different strategies. These two constructs were named MFVIIIC-16 and MFVIIIC-17. The constructs were linearized and transfected into strain 129 mouse ES cells by electroporation. Factor VIII gene-knockout ES cell lines were selected by G-418 and screened by genomic Southern blots. Eight exon 16 targeted cell lines and five exon 17 targeted cell lines were obtained. Three cell lines from each construct were injected into blastocysts and surgically transferred into foster mothers. Multiple chimeric mice with 70-90% hair color derived from the ES-cell genotype were seen with both constructs. Germ line transmission of the ES-cell genotype has been obtained for the MFVIIIC-16 construct, and multiple hemophilia A carrier females have been identified. Factor VIII-deficient males will be conceived soon.

  14. Historical intensity VIII earthquakes along the Rhone valley (Valais, Switzerland): primary and secondary effects

    Energy Technology Data Exchange (ETDEWEB)

    Fritsche, S.; Faeh, D.; Schwarz-Zanetti, G.

    2012-06-15

    In recent years the upper Rhone Valley has been one of the most intensively investigated regions by the Swiss Seismological Service. The high seismicity in the region encourages research in the seismological field and one main focus has been historical seismology. This report presents the state of the art of our historical investigations by giving an overview of the effects of four damaging earthquakes with intensity larger than VII, for which a fairly large number of documents could be found and analyzed. The overview includes the events of 1584 (Aigle, epicentral intensity VIII), 1755 (Brig, epicentral intensity VIII), 1855 (Visp, epicentral intensity VIII), and 1946 (Sierre, epicentral intensity VIII for the main shock and intensity VII for the largest aftershock). The paper focuses mainly on primary and secondary effects in the epicentral region, providing the key data and a general characterization of the event. Generally, primary effects such as the reaction of the population and impact on buildings took more focus in the past. Thus building damage is more frequently described in historic documents. However, we also found a number of sources describing secondary effects such as landslides, snow avalanches, and liquefaction. Since the sources may be useful, we include citations of these documents. The 1584 Aigle event, for example, produced exceptional movements in the Lake of Geneva, which can be explained by an expanded sub aquatic slide with resultant tsunami and seiche. The strongest of the aftershocks of the 1584 event triggered a destructive landslide covering the villages Corbeyrier and Yvorne, Vaud. All macroseismic data on the discussed events are accessible through the web page of the Swiss Seismological Service (http://www.seismo.ethz.ch). (authors)

  15. The impact of von Willebrand factor on factor VIII memory immune responses

    OpenAIRE

    Chen, Juan; Schroeder, Jocelyn A.; Luo, Xiaofeng; Shi, Qizhen

    2017-01-01

    Immune tolerance induction (ITI) with aggressive infusion of factor VIII (FVIII) is the current strategy used to eradicate FVIII inhibitors and restore normal FVIII pharmacokinetics in inhibitor patients. Whether the use of FVIII products containing von Willebrand factor (VWF) will affect the efficacy of ITI is still controversial. In this study, we explored the impact of VWF on FVIII memory immune responses in hemophilia A (HA) mice. A T-cell proliferation assay and cytokine profile analysis...

  16. Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia

    OpenAIRE

    Sejersted, Yngve; Hildrestrand, Gunn A.; Kunke, David; Rolseth, Veslemøy; Krokeide, Silje Z.; Neurauter, Christine G.; Suganthan, Rajikala; Atneosen-Åsegg, Monica; Fleming, Aaron M.; Saugstad, Ola D.; Burrows, Cynthia J.; Luna, Luisa; Bjørås, Magnar

    2011-01-01

    Neural stem/progenitor cell proliferation and differentiation are required to replace damaged neurons and regain brain function after hypoxic-ischemic events. DNA base lesions accumulating during hypoxic-ischemic stress are removed by DNA glycosylases in the base-excision repair pathway to prevent cytotoxicity and mutagenesis. Expression of the DNA glycosylase endonuclease VIII-like 3 (Neil3) is confined to regenerative subregions in the embryonic and perinatal brains. Here we show profound n...

  17. San Language Development for Education in South Africa: The South African San Institute and the San Language Committees

    Science.gov (United States)

    Pamo, Billies

    2011-01-01

    This article focuses on the 3 San communities in South Africa: the !Xun, the Khwe, and the [image omitted]Khomani San. The !Xun and Khwe communities are living in Platfontein, near Kimberley in the Northern Cape. The [image omitted]Khomani San community is living in Upington and in the southern Kalahari, which are also in the Northern Cape. This…

  18. San Jorge, el primer rejoneador

    OpenAIRE

    Mandianes Castro, Manuel

    2008-01-01

    Las proezas de Jorge son una réplica de las de Santiago. Este luchó y venció las serpientes que habitaban Galicia para entrar allí y convertirla al cristianismo. San Jorge venció al monstruo del lago, y el rey y los habitantes de Silca se convirtieron a Cristo. Santiago ganó el nombre de Matamoros y de soldado de Cristo por excelencia porque, montado en su caballo blanco, venció en 1.000 batallas a los moros al frente de los cristianos. San Jorge venció a los sarracenos y conquistó Jerusalén ...

  19. Structural characterization of the novel aminoglycoside phosphotransferase AphVIII from Streptomyces rimosus with enzymatic activity modulated by phosphorylation

    Energy Technology Data Exchange (ETDEWEB)

    Boyko, Konstantin M., E-mail: kmb@inbi.ras.ru [Bach Institute of Biochemistry, Federal Research Centre of Biotechnology of the Russian Academy of Sciences, Leninsky Prospekt. 33, Bld. 2, 119071, Moscow (Russian Federation); National Research Center “Kurchatov Institute”, Kurchatov Complex of NBICS-technologies, Akad. Kurchatova sqr., 1, Moscow, 123182 (Russian Federation); Gorbacheva, Marina A.; Korzhenevskiy, Dmitry A. [National Research Center “Kurchatov Institute”, Kurchatov Complex of NBICS-technologies, Akad. Kurchatova sqr., 1, Moscow, 123182 (Russian Federation); Alekseeva, Maria G.; Mavletova, Dilara A.; Zakharevich, Natalia V.; Elizarov, Sergey M.; Rudakova, Natalia N.; Danilenko, Valery N. [Vavilov Institute of General Genetics, Russian Academy of Sciences, Gubkina str. 3, Moscow, 119333 (Russian Federation); Popov, Vladimir O. [Bach Institute of Biochemistry, Federal Research Centre of Biotechnology of the Russian Academy of Sciences, Leninsky Prospekt. 33, Bld. 2, 119071, Moscow (Russian Federation); National Research Center “Kurchatov Institute”, Kurchatov Complex of NBICS-technologies, Akad. Kurchatova sqr., 1, Moscow, 123182 (Russian Federation)

    2016-09-02

    Aminoglycoside phosphotransferases represent a broad class of enzymes that promote bacterial resistance to aminoglycoside antibiotics via the phosphorylation of hydroxyl groups in the latter. Here we report the spatial structure of the 3′-aminoglycoside phosphotransferase of novel VIII class (AphVIII) solved by X-ray diffraction method with a resolution of 2.15 Å. Deep analysis of APHVIII structure and its comparison with known structures of aminoglycoside phosphotransferases of various types reveals that AphVIII has a typical two-domain fold and, however, possesses some unique characteristics that distinguish the enzyme from its known homologues. The most important difference is the presence of the activation loop with unique Ser146 residue. We demonstrate that in the apo-state of the enzyme the activation loop does not interact with other parts of the enzyme and seems to adopt catalytically competent state only after substrate binding. - Highlights: • 3D structure of the novel aminoglycoside phosphotransferase AphVIII was obtained. • AphVIII activation loop is clearly identified in the electron density. • AphVIII has some unique structural features in its substrate C-ring binding pocket.

  20. Neonatal helper-dependent adenoviral vector gene therapy mediates correction of hemophilia A and tolerance to human factor VIII.

    Science.gov (United States)

    Hu, Chuhong; Cela, Racel G; Suzuki, Masataka; Lee, Brendan; Lipshutz, Gerald S

    2011-02-01

    Neonatal gene therapy is a promising strategy for treating a number of congenital diseases diagnosed shortly after birth as expression of therapeutic proteins during postnatal life may limit the pathologic consequences and result in a potential "cure." Hemophilia A is often complicated by the development of antibodies to recombinant protein resulting in treatment failure. Neonatal administration of vectors may avoid inhibitory antibody formation to factor VIII (FVIII) by taking advantage of immune immaturity. A helper-dependent adenoviral vector expressing human factor VIII was administered i.v. to neonatal hemophilia A knockout mice. Three days later, mice produced high levels of FVIII. Levels declined rapidly with animal growth to 5 wk of age with stable factor VIII expression thereafter to >1 y of age. Decline in factor VIII expression was not related to cell-mediated or humoral responses with lack of development of antibodies to capsid or human factor VIII proteins. Subsequent readministration and augmentation of expression was possible as operational tolerance was established to factor VIII without development of inhibitors; however, protective immunity to adenovirus remained.

  1. Solidarity According to the Thought of Fr. Pedro Arrupe and Its Application to Jesuit Higher Education Today

    Science.gov (United States)

    Menkhaus, James

    2013-01-01

    Fr. Pedro Arrupe, S.J. was elected the 28th superior general of the Society of Jesus in 1965 and served in that role until 1983. As superior general, Arrupe sought to shape the Jesuits in the spirit of the vision of Vatican II, as well as the original charism of the founder of the Jesuit, St. Ignatius. The questions this dissertation seeks to…

  2. Vegetation - San Felipe Valley [ds172

    Data.gov (United States)

    California Department of Resources — This Vegetation Map of the San Felipe Valley Wildlife Area in San Diego County, California is based on vegetation samples collected in the field in 2002 and 2005 and...

  3. The San Bernabe power substation; La subestacion San Bernabe

    Energy Technology Data Exchange (ETDEWEB)

    Chavez Sanudo, Andres D. [Luz y Fuerza del Centro, Mexico, D. F. (Mexico)

    1997-12-31

    The first planning studies that gave rise to the San Bernabe substation go back to year 1985. The main circumstance that supports this decision is the gradual restriction for electric power generation that has been suffering the Miguel Aleman Hydro System, until its complete disappearance, to give priority to the potable water supply through the Cutzamala pumping system, that feeds in an important way Mexico City and the State of Mexico. In this document the author describes the construction project of the San Bernabe Substation; mention is made of the technological experiences obtained during the construction and its geographical location is shown, as well as the one line diagram of the same [Espanol] Los primeros estudios de planeacion que dieron origen a la subestacion San Bernabe se remontan al ano de 1985. La circunstancia principal que soporta esta decision es la restriccion paulatina para generar energia que ha venido experimentando el Sistema Hidroelectrico Miguel Aleman, hasta su desaparicion total, para dar prioridad al suministro de agua potable por medio del sistema de bombeo Cutzamala, que alimenta en forma importante a la Ciudad de Mexico y al Estado de Mexico. En este documento el autor describe el proyecto de construccion de la subestacion San Bernabe; se mencionan las experiencias tecnologicas obtenidas durante su construccion y se ilustra su ubicacion geografica, asi como un diagrama unifilar de la misma

  4. A close insight to factor VIII inhibitor in the congenital hemophilia A.

    Science.gov (United States)

    Tabriznia-Tabrizi, Shamsoreza; Gholampour, Marzie; Mansouritorghabeh, Hassan

    2016-09-01

    Hemophilia A (HA) has an X-linked pattern of inheritance and is the most common of the hemorrhagic disorders. HA is caused by a decreased or deficiency of the functional clotting factor VIII (FVIII) and effects 1 in 5000-10,000 male births. The common treatment for hemophilia is replacement therapy by plasma-derived or recombinant FVIII. Approximately 20-30% of people with a severe type of HA develop an inhibitor and this phenomenon is the main challenge in the management of these patients. Genetic factors and environmental determinants contribute to inhibitor development. Here, the roles of various genetic and environmental factors such as the type of FVIII concentrate used, the number of exposure days, and peak treatment time will be discussed in detail. It seems this information is helpful for hematologists. A literature review was done in January 2016 on PubMed and Scopus using the following keywords:' h(a)emophilia A & factor VIII inhibitor', 'h(a)emophilia A & factor VIII alloantibody', 'h(a)emophilia A & inhibitor'. There was no time limitation; however, there was an English language limitation placed on the articles selected. Expert commentary: Influential genetic and environmental factors in developing inhibitors have been discussed. Most of the risk factors are related to previously untreated patients with hemophili.

  5. [Structure and function of the factor VIII/von Willebrand factor complex].

    Science.gov (United States)

    Müller, G

    1990-03-01

    In the blood plasma factor VIII is bound to the von Willebrand factor. The primary structure of the two proteins were clarified by gene clonation. Factor VIII descends from a precursor protein with 2,351 amino acids by splitting of 19 amino acid residues and is activated by partial proteolysis. In the blood coagulation factor VIII acts as co-factor for the activation of factor X by factor IX in the presence of phospholipids and Ca++ within the intrinsic coagulation system. The formation of the von Willebrand factor takes place by splitting of 22 and 741 amino acid residues, respectively, from pre-pro-von Willebrand factor via pro-von Willebrand factor. The subunits of the von Willebrand factor consist od 2,050 amino acid residues. In the blood plasma the von Willebrand factor is existing as a mixture of multimeres. Receptors of the von Willebrand factor on the thrombocytic membrane are the glycoproteins GPIb and GPIIb/GPIIIa, by means of which the adhesion of thrombocytes at the subendoethelium of the vascular wall and the aggregation of thrombocytes are mediated.

  6. 76 FR 45693 - Safety Zone; San Diego POPS Fireworks, San Diego, CA

    Science.gov (United States)

    2011-08-01

    ... SECURITY Coast Guard 33 CFR Part 165 RIN 1625-AA00 Safety Zone; San Diego POPS Fireworks, San Diego, CA... temporary safety zone on the navigable waters of San Diego Bay in support of the San Diego POPS Fireworks..., participating vessels, and other vessels and users of the waterway during scheduled fireworks events. Persons...

  7. El retablo mayor de la parroquial de Vallecas (Madrid : una arquitectura desaparecida de Pedro y Francisco de la Torre (1672

    Directory of Open Access Journals (Sweden)

    Antonio José Díaz Fernández

    2004-01-01

    Full Text Available Como obra inédita dentro del catálogo de realizaciones del arquitecto y ensamblador de retablos Pedro de la Torre (1596-1677, uno de los principales artistas conformadores del arte barroco en el Madrid del siglo XVII, se ha de datar en 1672 el desaparecido retablo mayor de la iglesia parroquial de S. Pedro de Vallecas (Madrid, conocido hoy por fotografía, en el que intervienen otros artistas relevantes que aquí se documentan.As an unknown work belonging to the catalogue of performances of the architect and joiner of «retablos» Pedro de la Torre (1596-1677, one of the main creators of the baroque art at the Madrid of the XVIIth century, it’s possible to date in 1672 the missing main altarpiece of the S. Pedro’s church of Vallecas (Madrid, just known by photograph nowadays, where other important artists worked and are documented here.

  8. In Possession of a Stolen Weapon: From John Gay’s Macheath to Rubén Blades’ Pedro Navaja

    Directory of Open Access Journals (Sweden)

    Antonio Viselli

    2012-05-01

    Full Text Available This article analyses the cult salsa song “Pedro Navaja” by Panamanian artist Rubén Blades and the relevance of narrating such a genre peculiar to dancing, an re-writing of “Mack the Knife” – or Die Moritat von Mackie Messer – one which contains, as a sort of mise-en-abyme, elements not only of Kurt Weill’s song, but of both John Gay’s The Beggar’s Opera and Bertolt Brecht’s The Threepenny Opera. This study focuses on the fertile adaptation history of the highwayman Macheath since Gay’s work, on close-readings of “Pedro Navaja” – a narrativized cerebral salsa song – and on the ethics of adapting a character, story or genre. Finally, when the character Pedro Navaja is adapted from Blades’ song by a cineaste and playwright, Blades, furious with what others have done with ‘his’ character, decides to resuscitate his eponymous hero killed off at the end of the original song in order to regain the authority of his creation. From theoretical questions including how to read an adaptation or what constitutes an adaptation, this article focuses on the diachronic recurrences of a specific character-type, on the significance of juxtaposing particular historical junctures and on the violence of adaptation and authorship.

  9. The decline of Dom Pedro II's empire and health: neurophatogenic implications O declínio do império e da saúde de Dom Pedro II: implicações neuropatogênicas

    Directory of Open Access Journals (Sweden)

    Marleide da Mota Gomes

    2007-12-01

    Full Text Available The main objective of this paper is to know the medical doctors of the Emperor, the preconized treatment, and the knowledge about diabetes at that time, its repercussions on the Emperor's nervous system, and the related political implications. A narrative revision was made, based on primary and secondary sources. Dom Pedro II was examined by the aristocracy of the medicine at the time, especially Jean-Martin Charcot, amongst the doctors of international reputation, and Cláudio Velho da Motta Maia, amongst the Brazilian doctors. Charcot diagnosed in the Monarch: mental stress, diabetic neuropathy, and a cerebral vascular lesion, probably a stroke, that he differentiated from other vascular obliterations elsewhere. He demonstrated his knowledge about diabetic neuropathy, possible topographical alternatives to justify the urinary incontinence, and Dom Pedro's weakness in the legs. Throughout his illness, Dom Pedro II presented others manifestations that contributed to his physical fragility, and that, certainly too, to his political decline, deposition and the proclamation of the Brazilian Republic.O objetivo principal deste artigo é conhecer os médicos do Imperador, o tratamento preconizado e o conhecimento da ocasião sobre o diabetes, principalmente sobre suas repercussões no sistema nervoso do imperador e suas implicações políticas. Isso foi feito por uma revisão narrativa, baseado em fontes primárias e secundárias. Dom Pedro II foi examinado na ocasião pela aristocracia da medicina, a ressaltar Jean-Martin Charcot, dentre os médicos de reputação internacional, e Cláudio Velho da Motta Maia, dentre os brasileiros. Charcot diagnosticou no Monarca, além de tensão mental, neuropatia diabética e quadro vascular cerebral que ele diferenciou de outras obliterações vasculares em localizações diversas. Ele demonstrou o seu conhecimento sobre a neuropatia diabética, possíveis alternativas topográficas para justificar a incontin

  10. 27 CFR 9.157 - San Francisco Bay.

    Science.gov (United States)

    2010-04-01

    ..., San Mateo, Santa Clara, Alameda, and Contra Costa, which border the San Francisco Bay. The area also... proceed along the San Francisco, San Mateo, and Santa Cruz County shoreline (across the Quadrangles of San... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false San Francisco Bay. 9.157...

  11. Cartografia e deficiência visual: experiências no Colégio Pedro II

    Directory of Open Access Journals (Sweden)

    Rafael Medeiros de Andrade

    2014-01-01

    Full Text Available O processo de construção de uma escola inclusiva perpassa um conjunto de esforços cognitivos e técnicos por parte da comunidade escolar que são necessários para a adequada educação e desenvolvimento do aluno. No que diz respeito ao ensino de Geografia para alunos deficientes visuais, fazem parte deste conjunto de medidas o domínio do sistema Braille, a confecção de materiais e mapas táteis, a gravação de textos em áudio e, entre outras, a realização de trabalhos de campo. O presente relato de experiência refere-se à um projeto de dedicação exclusiva, implementado no Colégio Pedro II de 2008 a 2010, cujo objetivo foi aprimorar o ensino de Geografia para os alunos deficientes visuais. Conclui-se que a adoção dessas medidas representa o início de um longo trabalho de toda comunidade escolar que não pode ser resumido à existência de alguns materiais táteis. Deve, por outro lado, envolver um processo de construção e adequação instrumental, acompanhado da capacitação profissional e da sensibilização da comunidade escolar.

  12. Gothic Fiction Elements in Pedro Almodóvar’s The Skin I Live In (2011

    Directory of Open Access Journals (Sweden)

    Jelena Pataki

    2016-12-01

    Full Text Available The aim of this paper is to explore the elements of Gothic fiction in the critically acclaimed Spanish director Pedro Almodóvar’s 2011 film The Skin I Live In. The film is often viewed as a distinctly modern piece of art in that it dwells on contemporary issues referring to complex ethical and moral dilemmas connected to genetic engineering and the disintegration of an individual’s identity. However, despite the undeniable presence of the said issues, the idea is to show that the film’s structure is in fact solidly built on a much older Gothic fiction matrix featuring many of its well-established, easily discernible motifs and conventions. Starting with the classic Gothic topos – a helpless heroine set in an eerie, claustrophobic architecture, and a grotesque atmosphere evoking a feeling of imminent doom – the paper will consider the film’s portrayal of concepts such as death, doubles, and dreams in order to show that the work of the Spanish director bears many similarities to the canonical Anglophone genre. Inevitably, the analysis will also examine the distinct parallel between Mary Shelley’s seminal Gothic fiction text, Frankenstein, and the contemporary counterparts of its mad scientist and his Creation embodied by Almodóvar’s Dr Robert Ledgard and his Vera.

  13. De um escritor escrevente: “O amor de Pedro por João”

    Directory of Open Access Journals (Sweden)

    Maria Iraci Cardoso Tuzzin

    2017-03-01

    Full Text Available O romance O amor de Pedro por João publicado no Brasil, em 1982, e escrito durante o exílio do escritor brasileiro Tabajara Ruas (1942 é analisado a partir da relação escritor/escrita. Tal correspondência é discutida por um viés que inclui as anotações de pesquisadores, como Avelar, Silverman e Santiago, entre outros. A observação da forma, do estilo e das temáticas empregadas pelo artista aponta para a complexidade de questões referentes à profissão “escritor” em um contexto histórico pleno de cerceamento de liberdades situado entre os anos 1960 e 1980. Além disso, suscita reflexões sobre procedimentos literários experimentais em um meio social em que se ampliaram o grau e o controle da informação, apontando, deste modo, ligações entre a Literatura e a História.

  14. Information systems in health: a conversation with Pedro Urra González

    Directory of Open Access Journals (Sweden)

    Pedro Urra González

    2011-01-01

    Full Text Available En esta charla realizada en La Habana, en octubre de 2010, Pedro Urra González narra el contexto de surgimiento del Sistema Nacional de Información en Ciencias de la Salud de Cuba en la década del '60 y del proyecto Infomed, del cual fue fundador, a inicios de los años '90. Describe los fundamentos epistemológicos que sustentaron el desarrollo de Infomed como un proceso social y cultural, como espacio de integración de los esfuerzos del conocimiento, basado en una teoría del conocimiento orientada a responder a las necesidades de la práctica y la transformación. A partir de su concepción de los sistemas de información, entendidos como construcciones humanas, sociales e históricas que por lo tanto no pueden ser trasladados como artefactos desconectados de su realidad, analiza los indicadores bibliométricos, el movimiento Open Access y los proyectos regionales como la Scientific Electronic Library Online (SciELO y la Red de Revistas Científicas de América Latina y el Caribe, España y Portugal (Redalyc.

  15. Pedro Antonio Somellera y su concepción utilitarista del derecho

    Directory of Open Access Journals (Sweden)

    Martín Laclau

    2014-07-01

    Full Text Available En las primeras décadas del siglo XIX, fue perceptible el notable influjo y difusión que cobraron las concepciones reformistas de Jeremy Bentham, tanto en el campo de las ideas morales y políticas como en el de las instituciones jurídicas. En su doctrina, todos los productos de la actividad legislativa e institucional eran evaluados desde la perspectiva de la utilidad, considerando que la utilidad de las instituciones debia ser medida por el grado con que ellas contribuyesen al logro de la mayor felicidad del mayor número posible de individuos.(...(...Veamos, a continuación, en forma sumaria, el sentido y las líneas generales de su pensamiento, para comprobar como el mismo se refleja en las doctrinas jurídicas expuestas por Pedro Somellera en sus Principios de Derecho Civil.

  16. Use of biofilm in the postharvest conservation of 'Pedro Sato' guava

    Directory of Open Access Journals (Sweden)

    Danielle Fabíola Pereira Silva

    2012-06-01

    Full Text Available This present work aimed to assess the effect of different concentrations of cassava starch, associated or not with prochloraz fungicide, on the postharvest conservation of 'Pedro Sato' guavas. Physiologically mature fruits were immersed in a solution of prochloraz (49.5 g/100 liters of water for 5 min. Fruit treated with distilled water and air dried were used as control. They were immersed in cassava starch suspension at concentrations of 0, 20, 30 and 40 g/L, plus 0.5 mL/L of mineral oil. The fruits were stored at 21.0 ± 1.0 ºC and relative humidity of 85 ± 5%, for 12 days, and were examined at every three days. The combination of prochloraz and cassava starch resulted in delayed loss of firmness and yellowness and inhibited the incidence of lesions caused by Colletotrichum gloeosporioides during the 12 days of storage. Fruits treated with 40 g/L of starch, whether containing prochloraz or not, had unpleasant taste and odor, which suggests the occurrence of fermentation. Control fruits, with and without prochloraz, and those treated with starch with no prochloraz, had nearly 100% lesion occurrence within the 12 days. Starch suspension of 30 g/L, containing prochloraz, was the most effective in maintaining fruit quality.

  17. Tolerance to chilling and postharvest quality of ‘Pedro Sato’ guavas submitted to thermal conditioning

    Directory of Open Access Journals (Sweden)

    Ricardo Chechi

    2008-09-01

    Full Text Available The objective of this work was to evaluate the effect of thermal conditioning on the chilling tolerance and quality of ‘Pedro Sato’ guavas stored at 2ºC. The treatments evaluated were: 30 days at 10ºC (control; 30 days at 2ºC; one day at 45ºC + 29 days at 2ºC; two days at 45ºC + 28 days at 2ºC; two days at 35ºC + 28 days at 2ºC. After 30 days of storage plus three days at 20ºC, the firmness of the flesh and the titratable acidity were highest in the treatments with thermal conditioning. The incidence of rot was higher in fruits stored for 30 days at 10ºC and those kept for two days at 35ºC, and weight loss was higher in fruits kept for two days at 45ºC. Fruits stored for 30 days at 2ºC and those kept at 45ºC, before storage at 2ºC, did not show substantial alterations in the color of the peel during storage or shelf life, which can be associated with chilling injury.

  18. PENINGKATAN PEMBELAJARAN MENULIS PUISI BEBAS MELALUI MEDIA LAGU MEDLEY SISWA KELAS VIII SMP SINTANG

    Directory of Open Access Journals (Sweden)

    Rohanawati Silalahi

    2015-05-01

    Full Text Available Penelitian ini bertujuan untuk meningkatkan pembelajaran menulis puisi bebas melalui media lagu medley siswa kelas VIII B SMP Sintang. Subjek penelitian adalah siswa kelas VIII B SMP Sintang. Penelitian ini merupakan Penelitian Tindakan Kelas (PTK. Prosedur pelaksanaan dan implementasi penelitian dilaksanakan dalam dua siklus. Teknik pengumpulan data berupa obsevasi, wawancara, catatan lapangan, angket, evaluasi dan dokumentasi. Instrumen pengumpulan data meliputi lembar wawancara, lembar catatan lapangan, lembar angket, lembar tes hasil belajar dan lembar portofolio serta dokumentasi foto kegiatan. Teknik analisis data yang digunakan adalah analisis data kuantitatif dan kualitatif. Hasil penelitian ini menunjukkan bahwa penggunaan media lagu medley dapat meningkatkan pembelajaran menulis puisi bebas. Peningkatan hasil atau produk dapat dilihat dari perbandingan skor rata-rata keterampilan menulis puisi bebas siswa pada setiap siklus. Nilai rata-rata siswa pada tahap pratindakan adalah 55,23, pada saat siklus I meningkat menjadi 71,18, dan pada siklus II meningkat menjadi 73,4. ___________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________ DEVELOPING THE TEACHING OF FREE VERSE WRITING THROUGH MEDLEY SONG MEDIA TO GRADE VIII STUDENTS OF SMP SINTANG   Abstract This study aims to improve the teaching of free verse writing through medley song media to Grade VIII B students of SMP Sintang. The research subjects were Grade VIII B students of SMP Sintang,. This was a classroom action research (CAR. The research procedure and implementation were conducted in two cycles. The data were collected through observations, field notes, questionnaires, evaluations, and documentations. The data collecting instruments included interview sheets, field note sheets

  19. Convair Astronautics, San Diego (California

    Directory of Open Access Journals (Sweden)

    Pereira & Luckmam, Arquitectos

    1960-05-01

    Full Text Available Este brillante y espectacular complejo industrial se ha creado especialmente para la investigación y fabricación de cohetes intercontinentales y vehículos del espacio de las Fuerzas Aéreas de los EE. UU., en las proximidades de San Diego y cerca del campo de pruebas de Sycamore Canyon.

  20. ASTER Flyby of San Francisco

    Science.gov (United States)

    2002-01-01

    The Advanced Spaceborne Thermal Emission and Reflection radiometer, ASTER, is an international project: the instrument was supplied by Japan's Ministry of International Trade and Industry. A joint US/Japan science team developed algorithms for science data products, and is validating instrument performance. With its 14 spectral bands, extremely high spatial resolution, and 15 meter along-track stereo capability, ASTER is the zoom lens of the Terra satellite. The primary mission goals are to characterize the Earth's surface; and to monitor dynamic events and processes that influence habitability at human scales. ASTER's monitoring and mapping capabilities are illustrated by this series of images of the San Francisco area. The visible and near infrared image reveals suspended sediment in the bays, vegetation health, and details of the urban environment. Flying over San Francisco (3.2MB) (high-res (18.3MB)), we see the downtown, and shadows of the large buildings. Past the Golden Gate Bridge and Alcatraz Island, we cross San Pablo Bay and enter Suisun Bay. Turning south, we fly over the Berkeley and Oakland Hills. Large salt evaporation ponds come into view at the south end of San Francisco Bay. We turn northward, and approach San Francisco Airport. Rather than landing and ending our flight, we see this is as only the beginning of a 6 year mission to better understand the habitability of the world on which we live. For more information: ASTER images through Visible Earth ASTER Web Site Image courtesy of MITI, ERSDAC, JAROS, and the U.S./Japan ASTER Science Team

  1. Territorial Governance and Social Innovation: The Cases of San Pedro Capula’s Artisanal Cheese and the Rice (Oryza Sativa of Morelos, Mexico

    Directory of Open Access Journals (Sweden)

    Jessica Mariela Tolentino Martínez

    2018-02-01

    Full Text Available Over the last thirty-five years, Mexico has maintained a trade liberalization policy which has depressed food production and has reconstructed the structure of the agri-food sector; this has generated a higher food dependence and insecurity. In order to face this structural change, new organizational and socio-productive dynamics have emerged in communities, which take into consideration food diversity, heritage and cultural conditions of rural areas. In this paper, we use the theoretical approach of Localized Agrifood Systems (LAFS and the operative concepts of governance and social innovation to analyze and understand the efforts that at the base of society are created to grant development of productive systems. Therefore, we present the results of an investigation based on the exploration of two LAFS cases; in these cases, different strategies to achieve development have been established: the elaboration of artisanal cheese in the state of Hidalgo, and the production of rice in the state of Morelos, Mexico. Research results show the importance of concepts such as Social Innovation (SI and Governance within the framework of localized agri-food systems in rural studies, this, in order to identify the needs and potentials of family farming and producer’s groups inside the new contexts generated by globalization and market liberation process.

  2. Evaluating hydrological response of future land cover change scenarios in the San Pedro River (U.S./Mexico) with the automated geospatial watershed assessment (AGWA) tool

    Science.gov (United States)

    William G. Kepner; I. Shea Burns; David C. Goodrich; D. Phillip Guertin; Gabriel S. Sidman; Lainie R. Levick; Wison W.S. Yee; Melissa M.A. Scianni; Clifton S. Meek; Jared B. Vollmer

    2016-01-01

    Long-term land-use and land cover change and their associated impacts pose critical challenges to sustaining vital hydrological ecosystem services for future generations. In this study, a methodology was developed to characterize potential hydrologic impacts from future urban growth through time. Future growth is represented by housing density maps generated in decadal...

  3. Moscas blancas y enemigos naturales asociados al cultivo de naranja bajo dos tipos de manejo sanitario en San Pedro, provincia de Buenos Aires

    National Research Council Canada - National Science Library

    Silvia N LÓPEZ; Gonzalo SEGADE

    2017-01-01

    ... (conventional and organic). The density of adults, parasitized and non-parasitized nymphs, species and density of predators and parasitoids, presence of sooty mold on leaf/fruit, fruit yield and applied agrochemicals were recorded monthly...

  4. La cocina tradicional regional como un elemento de identidad y desarrollo local. El caso de San Pedro El Saucito, Sonora, México

    Directory of Open Access Journals (Sweden)

    Juana María Meléndez Torres

    2010-01-01

    Full Text Available En este trabajo planteamos que el estudio de las cocinas tradicionales nos puede permitir conocer las características de la vida social, económica y productiva de los grupos sociales o de las comunidades en las cuales se desarrolla; así como aquellos cambios que han ocurrido en su estilo de vida y cómo éstos se reflejan en la alimentación y, en especial, en la desaparición o adaptación de saberes y prácticas culinarias. Por otra parte, se analiza cómo han influido para que se produzca la transformación alimentaria tanto la urbanización como la globalización y las nuevas condiciones del mercado. Así mismo, planteamos que las cocinas tradicionales regionales constituyen parte del patrimonio intangible de las sociedades y las comunidades, que son a su vez un elemento de identidad y una pieza fundamental de las economías regionales y locales y para ello se expone el caso de una comunidad rural inserta en un proceso de urbanización.

  5. Directional wave and temperature data from ten buoys at Santa Monica Bay, Point Dume and San Pedro, CA, 1998 - 2002 (NODC Accession 0000767)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Coastal Data Information Program (CDIP) is an extensive network for monitoring waves along the coastlines of the United States, with a strong emphasis on our...

  6. Blooms of Pseudo-nitzschia and Domoic Acid in the San Pedro Channel and Los Angeles Harbor Areas of the Southern California Bight, 2003–2004

    OpenAIRE

    Schnetzer, Astrid; Miller, Peter E.; Schaffner, Rebecca; Stauffer, Beth; Jones, Burton H.; Weisberg, Stephen B.; DiGiacomo, Paul M.; Berelson, William M.; David A. Caron

    2007-01-01

    Abundances of Pseudo-nitzschia spp. and concentrations of particulate domoic acid (DA) were determined in the Southern California Bight (SCB) along the coasts of Los Angeles and Orange Counties during spring and summer of 2003 and 2004. At least 1500 km2 were affected by a toxic event in May/June of 2003 when some of the highest particulate DA concentrations reported for US coastal waters were measured inside the Los Angeles harbor (12.7 μg DA L−1). Particulate DA levels were an order of magn...

  7. Tiwanaku influence and social inequality: A bioarchaeological, biogeochemical, and contextual analysis of the Larache cemetery, San Pedro de Atacama, Northern Chile.

    Science.gov (United States)

    Torres-Rouff, Christina; Knudson, Kelly J; Pestle, William J; Stovel, Emily M

    2015-12-01

    To assess the relationship between the Tiwanaku polity and the individuals buried at the Middle Horizon (∼AD500-1000) cemetery of Larache in northern Chile, a site that has been singled out as a potential elite foreign enclave. We explore this association through the skeletal remains of 48 individuals interred at the cemetery of Larache using bioarchaeological, biogeochemical, and artifactual evidence. Data from cranial modification practices, violent injury, and the mortuary assemblage are used to explore culturally constructed elements of status and identity, radiogenic strontium isotope analyses provide us with a perspective on the geographic origins of these individuals, and stable carbon and nitrogen analyses allow discussion of paleodiet and access to resources. Radiogenic strontium isotope values show the presence of multiple first generation migrants at Larache. Stable carbon and nitrogen isotope data reveal significant differences among individuals. The mortuary context reveals a standard pattern for the oases but also includes a series of unusual burials with abundant gold and few other objects. Interestingly, both local and nonlocal individuals with different head shapes had access to the differentiated burial context; however nonlocal individuals appear to be the only ones with a heavily maize-based diet. Our evidence shows that Larache served as a burial place for a diverse, yet culturally integrated and potentially elite segment of the Atacameño population, but not a foreign enclave as had been postulated. © 2015 Wiley Periodicals, Inc.

  8. Recuperación de pinturas murales en la iglesia del Monasterio de San Pedro de Cardeña (Burgos. Policromía : ornamento y simbolismo

    Directory of Open Access Journals (Sweden)

    Concepción Bengoechea Agustino

    2002-01-01

    Full Text Available A través de las pinturas murales recuperadas en la capilla de los Mártires del Monasterio Benedictino de Cárdena, se hace una aproximación a la iconografía y el simbolismo de los colores y las formas. Los elementos arquitectónicos se transforman, por medio de la policromía en volúmenes escultóricos con significado propio.Throughout the wall paintings recovered at the Chapel of the Martyrs in the Benedictine Monastery of Cárdena, an approach is held to the iconography and symbolism of colours and shapes. The architectural ítems are changed by polychrome inte sculptural volumes with a meaningful significance.

  9. Los recorridos de San Pedro y Santiago Apóstol: un elemento central en la recreación de la territorialidad nahua-popoluca

    Directory of Open Access Journals (Sweden)

    Emilia Velázquez H.

    2015-01-01

    Full Text Available En este artículo se explica cómo dos grupos indígenas que ha- bitan en dos municipios del sur de Veracruz y hablan diferentes lenguas —nahuas de Mecayapan y zoque-popolucas de Soteapan— construyeron un territorio compartido cuyo eje central fue el uso mancomunado de las tierras a lo largo de varios siglos. También se analizan los efectos que la reforma agraria tuvo en la desestructuración parcial de este territorio, marcando fronteras internas inexistentes hasta entonces. Se muestra, a la vez, cómo dos prácticas culturales —las visitas de los santos y las vela - ciones— han posibilitado la recreación simbólica del antiguo territorio nahua-popoluca pese a haber desaparecido el uso mancomunado de las tierras entre Mecayapan y Soteapan. El análisis se centra en los desfases y tensiones existentes entre, por un lado, las prácticas locales de apropiación del espacio y, por otra parte, las legislaciones y disposiciones administra - tivas del Estado. También se reflexiona sobre el papel que ciertas prácticas culturales —en este caso de origen religioso— tienen en la conformación de territorialidades que recrean territorios ya fragmentados.

  10. Reservoir Considerations and Direct Uses of São Pedro do Sul Hydromineral and Geothermal Field, Northern Portugal

    Science.gov (United States)

    Ferreira Gomes, L. M.; Neves Trota, A. P.; Sousa Oliveira, A.; Soares Almeida, S. M.

    2017-12-01

    São Pedro do Sul Hydromineral and Geothermal Field, located in the northern interior zone of Portugal (Lafões zone), has the greatest widespread utilization of geothermal energy in Portugal mainland and is the most important thermal centre from the economical revenues point of view, obtained from direct and indirect utilization of the thermal water, mostly for wellness, health, and leisure of human beings. Recent utilization includes district and greenhouses heating and even cosmetic applications. The Hydromineral Field includes two exploitable zones: the Termas and Vau Poles. The waters are recognised for their mineral and medicinal effects, since the time of the Romans about 2000 years ago and, later on, on the 12th century, by the first King of Portugal, D. Afonso Henriques. The traditional spring and the 500 m well (AC1), located in the Termas Pole, currently supplies artesian hot water flow of about 16.9 L/s with a temperature of 67 °C. Despite the low flow rate of the actual two exploration wells drilled in the Vau Pole, the geothermal potential is high; a new deep well is planned to be drilled in this zone where is expected to obtain fluid temperature of around 75 °C. The occurrence of São Pedro do Sul mineral water, included in the sulphurous type waters, are linked to Hercynian granitoids, emplaced between 290 and 321 Myr. There is a close relationship between the placement of the main hot springs and the Verin-Chaves-Penacova fault, namely Verin (Spain), Chaves, Moledo, and S. Pedro do Sul (Portugal) hot springs. Heat flow generated at shallow crustal zones by the radiogenic host mineral of the granitic rocks, added to the deep Earth heat flow, heats the cold water inflow along fractures. Open fracture network along the main faults allows the hot fluids reach the surface, thus giving chance to the occurrence of hot springs and mineralized cold springs. Coupling between fracture opening and density difference between cold water inflow and hot water

  11. Frequency and epitope specificity of anti-factor VIII C1 domain antibodies in acquired and congenital hemophilia A.

    Science.gov (United States)

    Kahle, Joerg; Orlowski, Aleksander; Stichel, Diana; Healey, John F; Parker, Ernest T; Jacquemin, Marc; Krause, Manuela; Tiede, Andreas; Schwabe, Dirk; Lollar, Pete; Königs, Christoph

    2017-08-10

    Several studies showed that neutralizing anti-factor VIII (anti-fVIII) antibodies (inhibitors) in patients with acquired hemophilia A (AHA) and congenital hemophilia A (HA) are primarily directed to the A2 and C2 domains. In this study, the frequency and epitope specificity of anti-C1 antibodies were analyzed in acquired and congenital hemophilia inhibitor patients (n = 178). The domain specificity of antibodies was studied by homolog-scanning mutagenesis (HSM) with single human domain human/porcine fVIII proteins and antibody binding to human A2, C1, and C2 domains presented as human serum albumin (HSA) fusion proteins. The analysis with HSA-fVIII domain proteins confirmed the results of the HSM approach but resulted in higher detection levels. The higher detection levels with HSA-fVIII domain proteins are a result of antibody cross-reactivity with human and porcine fVIII leading to false-negative HSM results. Overall, A2-, C1-, and C2-specific antibodies were detected in 23%, 78%, and 68% of patients with AHA (n = 115) and in 52%, 57%, and 81% of HA inhibitor patients (n = 63). Competitive binding of the human monoclonal antibody (mAb) LE2E9 revealed overlapping epitopes with murine C1-specific group A mAbs including 2A9. Mutational analyses identified distinct crucial binding residues for LE2E9 (E2066) and 2A9 (F2068) that are also recognized by anti-C1 antibodies present in patients with hemophilia. A strong contribution of LE2E9- and 2A9-like antibodies was particularly observed in patients with AHA. Overall, our study demonstrates that the C1 domain, in addition to the A2 and C2 domains, contributes significantly to the humoral anti-fVIII immune response in acquired and congenital hemophilia inhibitor patients. © 2017 by The American Society of Hematology.

  12. Dry-heat treatment process for enhancing viral safety of an antihemophilic factor VIII concentrate prepared from human plasma.

    Science.gov (United States)

    Kim, In Seop; Choi, Yong Woon; Kang, Yong; Sung, Hark Mo; Shin, Jeong Sup

    2008-05-01

    Viral safety is a prerequisite for manufacturing clinical antihemophilic factor VIII concentrates from human plasma. With particular regard to the hepatitis A virus (HAV), a terminal dry-heat treatment (100 degrees for 30 min) process, following lyophilization, was developed to improve the virus safety of a solvent/detergent-treated antihemophilic factor VIII concentrate. The loss of factor VIII activity during dry-heat treatment was of about 5%. No substantial changes were observed in the physical and biochemical characteristics of the dry-heat-treated factor VIII compared with those of the factor VIII before dry-heat treatment. The dry-heat-treated factor VIII was stable for up to 24 months at 4oC. The dry-heat treatment after lyophilization was an effective process for inactivating viruses. The HAV, murine encephalomyocarditis virus (EMCV), and human immunodeficiency virus (HIV) were completely inactivated to below detectable levels within 10 min of the dry-heat treatment. Bovine herpes virus (BHV) and bovine viral diarrhea virus (BVDV) were potentially sensitive to the treatment. However porcine parvovirus (PPV) was slightly resistant to the treatment. The log reduction factors achieved during lyophilization and dry-heat treatment were > or =5.55 for HAV, > or =5.87 for EMCV, > or =5.15 for HIV, 6.13 for BHV, 4.46 for BVDV, and 1.90 for PPV. These results indicate that dry-heat treatment improves the virus safety of factor VIII concentrates, without destroying the activity. Moreover, the treatment represents an effective measure for the inactivation of non-lipid-enveloped viruses, in particular HAV, which is resistant to solvent/detergent treatment.

  13. El Museo Pedagógico "José Pedro Varela" en Internet

    Directory of Open Access Journals (Sweden)

    Susana Maggioli

    2013-12-01

    Full Text Available Este trabajo propone hacer del Museo Pedagógico José Pedro Varela un Centro de Información interactivo a través del análisis de sus acervos bibliográficos y museísticos para su publicación en internet. La investigación incluye el enfoque de los siguientes aspectos: historia, actividades permanentes y temporales, exposiciones, salas, colecciones, servicios y publicaciones. Para lograr el acceso a los fondos museísticos se han implementado dos bases de datos: a Libros: la bilbioteca de investigación que contiene manuales de enseñanza y libros de pedagogía; y b Objet: objetos en exposición en diferentes salas, la cual permite la consulta interactiva a las imágenes y descripción respectivas a través de una interface de fácil manejo. Uno de los productos, el Sitio Web, refleja el tratamiento que se ha hecho de dichas áreas con el cual se pretende captar el interés del público diverso que puede acceder a él, a saber: investigadores, docentes, estudiantes de magisterio, niños, público en general, etc. a través de un portal interactivo, ágil, dinámico, de diseño modular, que incluye el uso de colores cálidos y atrayentes. El resultado que aquí se presenta es la primera etapa de un proyecto más embicioso que se encuentra en desarrollo y que culminará con la automatización de los acervos museísticos de la institución.

  14. JOSÉ PEDRO VARELA Y LA GESTACIÓN DE LA ESCUELA URUGUAYA

    Directory of Open Access Journals (Sweden)

    Jorge Bralich

    2011-01-01

    Full Text Available Nos proponemos destacar la importancia de José Pedro Varela en el concierto latinoamericano, como constructor del sistema escolar uruguayo. Este trabajo resume largas investigaciones sobre la obra y personalidad de Varela, realizadas años atrás y sintéticamente expresadas en nuestra obra "Varela" (1989. Dicha investigación se basó sustancialmente en la re-lectura de los escritos de aquel y la contextualización de los mismos en el ambiente social, político y económico en que vivió. De ello surgió que la imagen popularizada de Varela ha sido muy esquemática y no rescata lo complejo de su personalidad. En efecto, Varela, joven inteligente y dinámico, inspirado en la obra de Sarmiento, junto con varios jóvenes amigos impulsó la creación de un movimiento educacional (la "Sociedad de Amigos de la Educación Popular" que confluyó en la aprobación -por el Gobierno- de una Ley de Educación y en su designación como Inspector Nacional de Instrucción Pública en 1877. Su temprana muerte en 1879 no le impidió dejar sentada las bases de un sistema escolar, cuyas líneas generales se prolongarían a través de más de un siglo. Si bien no ha sido suficientemente reconocido a nivel internacional, en Uruguay -y en alguna medida, en el Río de la Plata- es una de las figuras destacadas de la historia educacional.

  15. Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

    Energy Technology Data Exchange (ETDEWEB)

    Chi Ki Ngo,J.; Huang, M.; Roth, D.; Furie, B.; Furie, B.

    2008-01-01

    Factor VIII is a procofactor that plays a critical role in blood coagulation, and is missing or defective in hemophilia A. We determined the X-ray crystal structure of B domain-deleted human factor VIII. This protein is composed of five globular domains and contains one Ca(2+) and two Cu(2+) ions. The three homologous A domains form a triangular heterotrimer where the A1 and A3 domains serve as the base and interact with the C2 and C1 domains, respectively. The structurally homologous C1 and C2 domains reveal membrane binding features. Based on biochemical studies, a model of the factor IXa-factor VIIIa complex was constructed by in silico docking. Factor IXa wraps across the side of factor VIII, and an extended interface spans the factor VIII heavy and light chains. This model provides insight into the activation of factor VIII and the interaction of factor VIIIa with factor IXa on the membrane surface.

  16. Crystal Structure of Human Factor VIII: Implications for the Formation of the Factor IXa-Factor VIIIa Complex

    Energy Technology Data Exchange (ETDEWEB)

    Ngo, J.C.; Huang, M.; Roth, D.A.; Furie, B.C.; Furie, B. (Wyeth); (MBL)

    2008-06-03

    Factor VIII is a procofactor that plays a critical role in blood coagulation, and is missing or defective in hemophilia A. We determined the X-ray crystal structure of B domain-deleted human factor VIII. This protein is composed of five globular domains and contains one Ca{sup 2+} and two Cu{sup 2+} ions. The three homologous A domains form a triangular heterotrimer where the A1 and A3 domains serve as the base and interact with the C2 and C1 domains, respectively. The structurally homologous C1 and C2 domains reveal membrane binding features. Based on biochemical studies, a model of the factor IXa-factor VIIIa complex was constructed by in silico docking. Factor IXa wraps across the side of factor VIII, and an extended interface spans the factor VIII heavy and light chains. This model provides insight into the activation of factor VIII and the interaction of factor VIIIa with factor IXa on the membrane surface.

  17. The philologist Pedro Martínez López: an imaginative liberal lampoonist | El filólogo Pedro Martínez López: un libelista liberal imaginativo

    OpenAIRE

    Aline Vauchelle-Haquet

    2006-01-01

    In 1830, the philologist Pedro Martínez López was forced to go into exile in France for political reasons. In 1832, he published Representación a Fernando VII, rey de España, a lampoon in which he made a whole string of accusations against the tyrant. At the end of the following year, he published España en 1833, al expirar Fernando VII, another lampoon in which he blamed the king's despotic reign for the country's disastrous situation and asserted that such abuses and injustices could only b...

  18. Preservação de goiabas ‘Pedro Sato’ armazenadas sob atmosfera modificada em refrigeração Preservation of "Pedro Sato" guavas stored under modified atmosphere and refrigeration

    Directory of Open Access Journals (Sweden)

    Ayd Mary Oshiro

    2012-06-01

    Full Text Available O objetivo do trabalho foi determinar os efeitos de revestimentos e temperaturas de armazenamento na preservação da pós-colheita de goiabas ‘Pedro Sato’. Os frutos foram revestidos em solução de quitosana (1 e 3% (m/v e gelatina (3% (m/v ou embalados em filme de PVC 17µm. Frutos que não receberem nenhum revestimento serviram como controle. As amostras foram armazenadas a 5°C e 10°C, ambas com UR 80 ± 5% e as avaliações realizadas ao 0, 7, 14, 21, 28 dias após o armazenamento. Para cada temperatura de armazenamento, o delineamento experimental empregado foi o inteiramente casualizado em esquema fatorial com quatro repetições. Os revestimentos comestíveis (gelatina e quitosana não foram eficientes no retardar do amadurecimento e prolongar a preservação e qualidade dos frutos de goiaba nas temperaturas de 5°C e 10°C. A utilização do filme de PVC reduziu a perda de massa e contribuiu para a manutenção dos teores de Vitamina C e açúcares totais de goiabas ‘Pedro Sato’ por 28 dias com armazenamento em 5°C e 10°C.The purpose of this work was to determine the effects of different coatings and storage temperatures in the post-harvest preservation of "Pedro Sato" guavas. The fruits were immerse in chitosan solution (1% and 3% (w/v, gelatin (3% (w/v, PVC film 17µm and those that did not receive any coating functioned as control and stored at 5°C and 10°C, both with UR 80 ± 5%, and the evaluations were performed at days 0, 7, 14, 21, and 28 after storage. For each storage temperature, the experimental outline applyed was entirely randomized in factorial squeme with four repetitions. The edible coatings (gelatin and chitosan were not eficient in slowing down the maturation and in extending the preservation and quality of the guava at 5°C and 10°C. The use of PVC film reduced mass loss and contributed to the maintenance of "Pedro Sato" guava’s vitamin C and total sugar levels for 28 days stored in both evaluated

  19. Analysis of inversions in the factor VIII gene in Spanish hemophilia A patients and families

    Energy Technology Data Exchange (ETDEWEB)

    Domenech, M.; Tizzano, E.; Baiget, M. [Hospital de Sant Pau, Barcelona (Spain); Altisent, C. [Hospital Vall d`Hebron, Barcelona (Spain)

    1994-09-01

    Intron 22 is the largest intron of the factor VIII gene and contains a CpG island from which two additional transcripts originate. One of these transcripts corresponds to the F8A gene which have telomeric extragenic copies in the X chromosome. An inversion involving homologous recombination between the intragenic and the distal or proximal copies of the F8A gene has been recently described as a common cause of severe hemophilia A (HA). We analyzed intron 22 rearrangements in 195 HA patients (123 familial and 72 sporadic cases). According to factor VIII levels, our sample was classified as severe in 114 cases, moderate in 29 cases and mild in 52 cases. An intron 22 (F8A) probe was hybridized to Southern blots of BcII digested DNA obtained from peripheral blood. A clear pattern of altered bands identifies distal or proximal inversions. We detected an abnormal pattern identifying an inversion in 49 (25%) of the analyzed cases. 43% of severe HA patients (49 cases) showed an inversion. As expected, no inversion was found in the moderate and mild group of patients. We found a high proportion (78%) of the distal rearrangement. From 49 identified inversions, 33 were found in familial cases (27%), while the remaining 15 were detected in sporadic patients (22%) in support that this mutational event occurs with a similar frequency in familial or sporadic cases. In addition, we detected a significant tendency of distal inversion to occur more frequently in familial cases than in sporadic cases. Inhibitor development to factor VIII was documented in approximately 1/3 of the patients with inversion. The identification of such a frequent molecular event in severe hemophilia A patients has been applied in our families to carrier and prenatal diagnosis, to determine the origin of the mutation in the sporadic cases and to detect the presence of germinal mosaicism.

  20. AKTIVITAS FISIK, ASUPAN ENERGI DAN STATUS GIZI WANITA PEMETIK TEH DI PTPN VIII BANDUNG, JAWA BARAT

    Directory of Open Access Journals (Sweden)

    Venny Agustiani Mahardikawati

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 Quality of human resources is very important to improve productivity. The worker productivity is correlated with nutritional status and health status. The objective of the research is to analyze physical activity, energy intake, nutritional status, of women workers at Tea Plantation PTPN VIII Bandung, West Java. The cross sectional design was used in this study to elaborate physical activity, nutritional status, and productivity of tea picker’s women. The criteria of study sample were tea picker’s women at cluster area of Malabar tea plantation of PTPN VIII Bandung, having infant and they were willing to be interviewed. The total number of 92 women sample was chosen randomly. Primary data consisted of physical activity recall (2x24 hours, food consumption recall (2x24 hours, anthropometry data (weight and height, and productivity (passage of tea sprout. Secondary data were included data of PT Perkebunan Nusantara VIII Bandung, West Java. The result showed that more than a half of samples having active or moderate physical activity level (PAL. The physical activity level of samples during work day (average PAL=1.87 was higher than holiday (average PAL=1.69 (p2362 kcal and 2134 kcal. The average energy adequacy level during workday and day off according to Schofield and Oxford equation were not significantly different, respectively 97,2% and 103,3%. The majority of samples had normal nutritional status, and 30.4% of the sample was overweight. The energy adequacy level according to Schofield and Oxford equation are related to nutritional status of women workers. Keywords: physical activity, energy expenditure, nutritional status, plantation women

  1. IMPLIKASI YURIDIS PUTUSAN MK NOMOR 46/PUU- VIII/ 2010 TERHADAP AKTA KELAHIRAN ANAK LUAR KAWIN

    Directory of Open Access Journals (Sweden)

    Djumikasih Djumikasih

    2014-08-01

    Full Text Available Abstract This paper aims to identify and analyze what the juridical implications of the publication of the decision of the Constitutional Court No. 46/PUU-VIII / 2010 on Child Outside Marriage Deed which has been published by the Department of Population and Civil Registration prior to the establishment of the Constitutional Court's decision . The method used in this study is a normative juridical approach legislation. From the discussion, it can be concluded that the Constitutional Court 46/PUU-VIII/2010 Number of Tests on Article 43 paragraph ( 1 Marriage Act ( Act No. 1 of 1974 when viewed from the angle of legal certainty it will lead to legal certainty . But the decision will not have any juridical implications of the child's birth certificate that has been published outside of marriage and illegitimate child who was born before the date of February 17, 2012, as if enacted would be contrary to the principle of legality is interpreted Article 47 of the Law on the Constitutional Court and Article 28 ( i of the 1945 Constitution . Likewise, if the terms of the fairness and usefulness , especially for justice seekers / applicant , the timing of this decision is not fair and not useful , because although the Court granted the petition but the Constitutional Court can not be applied to her .   Key words: yuridical implication, birth certificate, children who are born outside of marriage   Abstrak   Tulisan ini bertujuan untuk mengetahui dan menganalisis apa implikasi yuridis dari terbitnya putusan MK Nomor 46/PUU-VIII/ 2010 terhadap Akta Anak Luar Kawin yang sudah diterbitkan oleh Dinas Kependudukan dan Catatan Sipil sebelum lahirnya putusan MK tersebut. Metode yang digunakan dalam penelitian ini adalah yuridis normative dengan pendekatan perundang-undangan. Dari pembahasan dapat disimpulkan bahwa Putusan MK Nomer 46/PUU-VIII/2010 tentang Pengujian terhadap Pasal 43 ayat (1 UU Perkawinan (UU NO 1 Tahun 1974 jika dilihat dari sudut kepastian

  2. Underground Test Area Subproject Phase I Data Analysis Task. Volume VIII - Risk Assessment Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-12-01

    Volume VIII of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the risk assessment documentation. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  3. Comercio Internacional mediterráneo en el siglo VIII a.C.

    Directory of Open Access Journals (Sweden)

    Paloma Cabrera Bonet

    2018-01-01

    Full Text Available The VIII century B.C. saw, for the first time after the breakdown of the system in the Late Bronze Age, the revival of a true intemational trade at a growing scale, especíally protagonized by Phoenicians and Greeks. In this article we analyze sorne aspects of this phenomenon, from the Aegean to the Far West, which made possíble, through a vaste network of trading routes, a large multinational ínteractíon. We understand the international trade as a key factor in the proccess of economic, social and political changes of the Mediterranean areas submerged in this complex "world-system".

  4. Production of Lentiviral Vectors Encoding Recombinant Factor VIII Expression in Serum-Free Suspension Cultures

    Directory of Open Access Journals (Sweden)

    Angelo Luis Caron

    2015-12-01

    Full Text Available ABSTRACT Lentiviral vector-mediated gene transfer offers several advantages over other gene delivery vectors when considering gene and cell therapy applications. However, using these therapies in clinical applications involves large-scale vector production in an efficient and cost-effective manner. Here we describe a high yield production of a lentivirus encoding recombinant factor VIII in a scalable and GMP-compliant culture system, based on serum free suspension cultures and transient transfection with an inexpensive reagent, polyethylenimine (PEI, reaching a total viral yield of 2.48x108 particles.

  5. Measurements of Sheath Currents and Equilibrium Potential on the Explorer VIII Satellite (1960 xi)

    Science.gov (United States)

    Bourdeau, R. E.; Donley, J. L.; Serbu, G. P.; Whipple, E. C., Jr.

    1961-01-01

    Experimental data were obtained from the Explorer VIII satellite on five parameters pertinent to the problem of the interaction of space vehicles with an ionized atmosphere. The five parameters are: photoemission current due to electrons emitted from the satellite surfaces as a result of solar radiation; electron and positive ion currents due to the diffusion of charged particles from the medium to the spacecraft; the vehicle potential relative to the medium, and the ambient electron temperature. Included in the experimental data is the aspect dependence of the photoemission and diffusion currents. On the basis of the observations, certain characteristics of the satellite's plasma sheath are postulated.

  6. Indexing of randomised controlled trials of physiotherapy interventions: a comparison of AMED, CENTRAL, CINAHL, EMBASE, hooked on evidence, PEDro, PsycINFO and PubMed.

    Science.gov (United States)

    Moseley, Anne M; Sherrington, Catherine; Elkins, Mark R; Herbert, Robert D; Maher, Christopher G

    2009-09-01

    To compare the comprehensiveness of indexing the reports of randomised controlled trials of physiotherapy interventions by eight bibliographic databases (AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO and PubMed). Audit of bibliographic databases. Two hundred and eighty-one reports of randomised controlled trials of physiotherapy interventions were identified by screening the reference lists of 30 relevant systematic reviews published in four consecutive issues of the Cochrane Database of Systematic Reviews (Issue 3, 2007 to Issue 2, 2008). AMED, CENTRAL, CINAHL, EMBASE, Hooked on Evidence, PEDro, PsycINFO and PubMed were used to search for the trial reports. The number of trial reports indexed in each database was calculated. PEDro indexed 99% of the trial reports, CENTRAL indexed 98%, PubMed indexed 91%, EMBASE indexed 82%, CINAHL indexed 61%, Hooked on Evidence indexed 40%, AMED indexed 36% and PsycINFO indexed 17%. Most trial reports (92%) were indexed on four or more of the databases. One trial report was indexed on a single database (PEDro). Of the eight bibliographic databases examined, PEDro and CENTRAL provide the most comprehensive indexing of reports of randomised trials of physiotherapy interventions.

  7. UM OLHAR SOBRE OS CONFLITOS NO AMBIENTE ORGANIZACIONAL: entrevista com Dr. Pedro Fernando Santos Silva da Cunha.

    Directory of Open Access Journals (Sweden)

    Kamille Ramos Torres

    2017-01-01

    Full Text Available Nessa edição, a Revista Foco, por meio de Kamille Ramos Torres, traz uma entrevista com o Dr. Pedro Fernando Santos Silva da Cunha, professor associado com agregação da Universidade Fernando Pessoa em Portugal. Suas pesquisas versam sobre a Gestão de Conflitos, Negociação, Mediação, Paz, entre outros. Nessa entrevista, ele expõe sua trajetória profissional e acadêmica, e nos fornece um pouco do seu imenso conhecimento sobre a Mediação de Conflitos no ambiente organizacional.

  8. Libros adquiridos por don Pedro Fermín de Vargas en sus viajes por las Antillas

    Directory of Open Access Journals (Sweden)

    Sergio Elías Ortíz

    1962-04-01

    Full Text Available Entre los papeles relacionados con la vida de Don Pedro Fermín de Vargas, que pueden consultarse en el Archivo General de Indias de Sevilla, hay una carta de él y una lista de libros que envía al Administrador de Correos de la Habana, Don José Fuertes, antiguo amigo suyo, luego su corresponsal y a la  vez espía de sus pasos para aprisionarlo, con el objeto de que se los guardase “en algún rincón de sus casa”.

  9. Apropiación ciudadana de la ciencia y la tecnología. El caso de Pedro Figari.

    Directory of Open Access Journals (Sweden)

    Agustín Courtoisie

    2015-05-01

    Full Text Available La apropiación ciudadana de la ciencia y la tecnología suele ocupar la atención académica principalmente en lo referido al uso creciente de nuevas tecnologías y la horizontalidad  de las comunicaciones propias de la globalización.  El artículo procura complementar esa mirada con una perspectiva histórica y analiza la labor de Pedro Figari en el Uruguay como un caso de apropiación ejemplar.

  10. QUALIDADE DE GOIABAS ‘PEDRO SATO’ EM FUNÇÃO DE TRATAMENTOS ALTERNATIVOS EM PÓS-COLHEITA

    OpenAIRE

    MARIA CECÍLIA DE ARRUDA PALHARINI; IVAN HERMAN FISCHER; AGHATA REGINA DE OLIVEIRA FERREIRA ALVES; MIRIAN DE SOUZA FILETI; ANTÔNIO FERNANDES NOGUEIRA JÚNIOR

    2016-01-01

    RESUMO Este trabalho teve como objetivo avaliar o efeito de produtos alternativos e termoterapia, isoladamente e em associação, na qualidade físico-química e no controle das podridões de goiabas ‘Pedro Sato’. Inicialmente, foi avaliado o efeito dos tratamentos em pós-colheita com cloreto de cálcio, fosfito de potássio, 1-metilciclopropeno (1-MCP), fécula de mandioca, etanol seguido de cloro (etanol+cloro) e termoterapia, durante oito dias de armazenamento dos frutos a 22ºC. Em uma segunda et...

  11. QUALIDADE DE GOIABAS ‘PEDRO SATO’ EM FUNÇÃO DE TRATAMENTOS ALTERNATIVOS EM PÓS-COLHEITA

    OpenAIRE

    PALHARINI,MARIA CECÍLIA DE ARRUDA; FISCHER,IVAN HERMAN; ALVES,AGHATA REGINA DE OLIVEIRA FERREIRA; FILETI,MIRIAN DE SOUZA; NOGUEIRA JÚNIOR,ANTÔNIO FERNANDES

    2016-01-01

    RESUMO Este trabalho teve como objetivo avaliar o efeito de produtos alternativos e termoterapia, isoladamente e em associação, na qualidade físico-química e no controle das podridões de goiabas ‘Pedro Sato’. Inicialmente, foi avaliado o efeito dos tratamentos em pós-colheita com cloreto de cálcio, fosfito de potássio, 1-metilciclopropeno (1-MCP), fécula de mandioca, etanol seguido de cloro (etanol+cloro) e termoterapia, durante oito dias de armazenamento dos frutos a 22ºC. Em um...

  12. Pedro de Angelis / José Joaquín de Mora: displacements and repetition (1826 -1833

    Directory of Open Access Journals (Sweden)

    Rosalía Baltar

    2014-03-01

    Full Text Available Both Pedro de Angelis and José Joaquín de Mora start their American journeys towards the end of 1826. Bernardino Rivadavia has hired them to write a political and literary newspaper. The main aim of this article is to highlight the first actions of these men through their first journalist productions, Crónicapolítica y literaria y El Conciliador, the transition to the consolidation of their professional careers and  the analysis of them in some earlier productions.

  13. La censura española y la "recopilación historial" de Fray Pedro Aguado

    Directory of Open Access Journals (Sweden)

    Juan Friede

    1963-02-01

    Full Text Available De fray Pedro Aguado se sabe que fue insuperable cronista del Nuevo Reino de Granada. Su permanencia entre los indígenas por algo más de quince años le brindó excepcional oportunidad de conocer en sus más recónditos misterios la vida y costumbres de aquellos seres, de penetrar en sus conciencias por el camino de la predicación y de asistir al súbito desquiciamiento de milenarias tradiciones sociales y religiosas.

  14. Cross-media Transmission Processes. Marian Figures in Todo sobre mi madre (Pedro Almodóvar, ES 1999

    Directory of Open Access Journals (Sweden)

    Natalie Fritz

    2015-11-01

    Full Text Available This paper builds on aspects of the cultural studies perspective that understands art itself as a method of cultural analysis. This will be exemplified by focusing on how film as a cultural technique for framing and reframing the world, using its different audiovisual devices of representation, is an important contemporary agens in the process of transmitting religious motifs and concepts. The paper highlights how Pedro Almodóvar skillfully stimulates the audience to reflect on the polysemy and polyvalence of motifs by not only referring explicitly to iconographic traditions, but also playing with aesthetic conventions.

  15. Institución Educativa Técnico Industrial Pedro Antonio Molina: eje de desarrollo y bienestar para la comunidad

    OpenAIRE

    Álvarez Watson, Daniel Alberto; Bolaños Burbano, Henry Orlando; Velásquez Vásquez, Francisco Orlando

    2012-01-01

    El caso analiza la situación particular de la Institución educativa Técnico Industrial Pedro Antonio Molina, el liderazgo del rector y el apoyo del sector privado en los procesos de gestión de la calidad. Esto motiva a los integrantes de la institución a trabajar en equipo para lograr la certificación de calidad, mejorando sus resultados académicos año tras año, destacándose a nivel regional y nacional, y generando cambios sociales en su entorno. Metodológicamente, se identificó una instituci...

  16. Edition and Traslation of the «Carta a lord Burghley» by Pedro Sarmiento de Gamboa

    Directory of Open Access Journals (Sweden)

    Andrés Eichmann Oehrli

    2016-05-01

    Full Text Available In the following article we present an unpublished and unknown text of Galician discoverer Pedro Sarmiento de Gamboa. The letter, wrote in Latin, was send to Lord Burghley, the first minister of Elizabeth Tudor. Its content links chro-nicles and legends of Spain and Galicia to the genealogy of Sarmiento de Gamboa. Here, we offer the biographical context of the letter, a brief study of the sources, apart from the transcription of the original and the translation of the text into Spanish.

  17. Asume la presidencia de facto el general Pedro Eugenio Aramburu : Protagonista de la autodenominada Revolución Libertadora

    OpenAIRE

    Aramburu, Pedro Eugenio

    2013-01-01

    El general asume la presidencia, que dejaba otro militar, Eduardo Lonardi, en lo que políticamente resultó la profundización del antiperonismo. Recuerda a los caídos en los días de septiembre cuando se concretaba el golpe de estado contra el gobierno de Juan Domingo Perón. Pedro Eugenio Aramburu: (21 de mayo de 1903-1 de junio de 1970). Fue presidente de facto entre el 13 de noviembre de 1955 y el 1 de mayo de 1958. En 1970 fue secuestrado y asesinado por la agrupación "Montoneros".

  18. KEEFEKTIFAN MODEL TGT DENGAN PENDEKATAN SCIENTIFIC BERBANTUAN CD PEMBELAJARAN TERHADAP KEMAMPUAN PEMECAHAN MASALAH SISWA SMP KELAS VIII PADA MATERI LINGKARAN

    Directory of Open Access Journals (Sweden)

    Singgih Baswendro

    2015-11-01

    Full Text Available Artikel ini dibuat berdasarkan penelitian skripsi yang telah dilaksanakan. Tujuan penelitian ini adalah (1 untuk mengetahui hasil kemampuan pemecahan masalah siswa kelas VIII pada materi lingkaran dengan menggunakan model TGT mencapai KKM, dan (2 untuk mengetahui rata-rata kemampuan pemecahan masalah siswa dengan model TGT lebih tinggi daripada dengan model ekspositori. Penelitian ini dilaksanakan di SMP Negeri 3 Ungaran dengan populasi siswa kelas VIII tahun ajaran 2014/2015. Pengambilan kelas sampel menggunakan teknik cluster random sampling. Untuk mengetahui hasil penelitian ini, data hasil akhir diuji dengan uji proporsi dan uji perbedaan rata-rata. Hasil penelitan ini menunjukkan bahwa (1 hasil kemampuan pemecahan masalah siswa kelas VIII pada materi lingkaran dengan menggunakan model TGT mencapai KKM, dan (2 rata-rata kemampuan pemecahan masalah siswa dengan model TGT lebih tinggi daripada dengan model ekspositori. Dengan ini maka model TGT dengan pendekatan scientific berbantuan CD pembelajaran efektif terhadap kemampuan pemecahan masalah siswa.

  19. Potential field studies of the central San Luis Basin and San Juan Mountains, Colorado and New Mexico, and southern and western Afghanistan

    Science.gov (United States)

    Drenth, Benjamin John

    This dissertation includes three separate chapters, each demonstrating the interpretive utility of potential field (gravity and magnetic) geophysical datasets at various scales and in various geologic environments. The locations of these studies are the central San Luis Basin of Colorado and New Mexico, the San Juan Mountains of southwestern Colorado, and southern and western Afghanistan. The San Luis Basin is the northernmost of the major basins that make up the Rio Grande rift, and interpretation of gravity and aeromagnetic data reveals patterns of rifting, rift-sediment thicknesses, distribution of pre-rift volcanic and sedimentary rocks, and distribution of syn-rift volcanic rocks. Syn-rift Santa Fe Group sediments have a maximum thickness of ˜2 km in the Sanchez graben near the eastern margin of the basin along the central Sangre de Cristo fault zone. Under the Costilla Plains, thickness of these sediments is estimated to reach ˜1.3 km. The Santa Fe Group sediments also reach a thickness of nearly 1 km within the Monte Vista graben near the western basin margin along the San Juan Mountains. A narrow, north-south-trending structural high beneath San Pedro Mesa separates the graben from the structural depression beneath the Costilla Plains. Aeromagnetic anomalies are interpreted to mainly reflect variations of remanent magnetic polarity and burial depth of the 5.3-3.7 Ma Servilleta basalt of the Taos Plateau volcanic field. Magnetic-source depth estimates indicate patterns of subsidence following eruption of the basalt and show that the Sanchez graben has been the site of maximum subsidence. One of the largest and most pronounced gravity lows in North America lies over the rugged San Juan Mountains in southwestern Colorado. A buried, low-density silicic batholith related to an Oligocene volcanic field coincident with the San Juan Mountains has been the accepted interpretation of the source of the gravity low since the 1970s. However, this interpretation was

  20. Hans Blumenberg: Historia In/conceptual, Antropología y Modernidad, por Faustino Oncina y Pedro García-Durán, eds.

    OpenAIRE

    Meléndez, Ana

    2016-01-01

    Reseña de Oncina Coves, Faustino y García-Durán, Pedro (eds.) 2015, Hans Blumenberg: Historia in/conceptual, antropología y modernidad, Valencia: Pre-Textos. ISBN 978-84-16453-06-1, 240 páginas.   Ressenya de Oncina Coves, Faustino y García-Durán, Pedro (eds.) 2015, Hans Blumenberg: Historia in/conceptual, antropología y modernidad, Valencia: Pre-Textos. ISBN 978-84-16453-06-1, 240 pàgs.   Review of Oncina Coves, Faustino y García-Durán, Pedro (eds.) 2015, Hans Blumenberg: Historia in/c...

  1. Borrador de una representación de don Pedro Fermín de Vargas ante el Gobierno Británico

    Directory of Open Access Journals (Sweden)

    Sergio Elías Ortíz

    1961-10-01

    Full Text Available Entre los documentos comprometedores entregados al gobierno español (el primer plan de Miranda para la invasión a las costas de Venezuela, cartas del mismo y de don Pedro Gual, etc. por el traidor a la causa de la Independencia hispano-americana, don Pedro José Caro, cuando éste pidió clemencia al Rey, arrepentido de sus andanzas como revolucionario al servicio del Precursor Miranda, figuró también uno de puño y letra, con correcciones, del ilustre neogranadino don Pedro Fermín de Vargas, que era nada menos que "el borrador original de una de sus representaciones al gobierno británico".

  2. Indonesian Interference on English Language in VIII Grade Junior High School Students

    Directory of Open Access Journals (Sweden)

    Agustia Km Tri Sutrisna

    2018-01-01

    Full Text Available This study aims to determine the type of Indonesian interference found in English language among class VIII SMPK 2 Harapan Untal-Untal students. This research is done by analyzing the result of simple text translation done by the students of class VIII SMPK 2 Harapan Untal-Untal, then from the translation result will be analyzed what kind of interference that appeared. Methods of data collection in this study using observational research methods and literature. The data that have been collected in the form of simple translations from the students will be analyzed descriptively using related theories to find out what kind of interference found in the analysis. Further, in relating to interference, it will find a way out to reduce and even eliminate Indonesian interference itself. The results to be achieved in this research is recognize the level of Indonesian language interference in the use of English among the junior high school students, then find the practical efforts to be done so that interference does not increased. So, the use and English understanding can be done as much as possible. The finding of the paper found that 6 interference such as grammar structure, subject pronoun, adjectives, auxiliaries, preposition and word order.

  3. PENGEMBANGAN PERANGKAT AJAR MODEL CORE PENDEKATAN METAKOGNITIF UNTUK MENINGKATKAN KEMAMPUAN PEMECAHAN MASALAH GEOMETRI KELAS VIII

    Directory of Open Access Journals (Sweden)

    Daroinis Sa’adah

    2017-02-01

    Full Text Available The objectives of this study are to develop teaching aids, to test the validity and practically teaching aids, and to test the effectiveness of learning process using CORE (Connecting, Organizing, Reflecting, and Extending model with metacognitive approach to improve the ability in Geometri problem solving. This research and development design is adapted from Plomp model by using several phases: (1 preliminary investigation; (2 design; (3 realization/construction; (4 test, evaluation and revision. This study developed some teaching aids; a part of syllabus, lesson plan, students book, students’ work sheet, and test of problem solving ability. The subject of the try out is eighth graders of MTs NU Nurul Huda Kudus. The research data to test the validity, practically, and effectiveness are collected by: (1 validation sheet; (2 observation sheet; (3 problem solving test. The results of research showed that development teaching aids using CORE model with metacognitive approach for Geometry material of VIII grade is valid and practical, and learning CORE model with metacognitive approach for Geometry material of VIII grade is effective.

  4. Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A

    Directory of Open Access Journals (Sweden)

    Alexandra Sherman

    2017-11-01

    Full Text Available Hemophilia A (coagulation factor VIII deficiency is a debilitating genetic disorder that is primarily treated with intravenous replacement therapy. Despite a variety of factor VIII protein formulations available, the risk of developing anti-dug antibodies (“inhibitors” remains. Overall, 20–30% of patients with severe disease develop inhibitors. Current clinical immune tolerance induction protocols to eliminate inhibitors are not effective in all patients, and there are no prophylactic protocols to prevent the immune response. New experimental therapies, such as gene and cell therapies, show promising results in pre-clinical studies in animal models of hemophilia. Examples include hepatic gene transfer with viral vectors, genetically engineered regulatory T cells (Treg, in vivo Treg induction using immune modulatory drugs, and maternal antigen transfer. Furthermore, an oral tolerance protocol is being developed based on transgenic lettuce plants, which suppressed inhibitor formation in hemophilic mice and dogs. Hopefully, some of these innovative approaches will reduce the risk of and/or more effectively eliminate inhibitor formation in future treatment of hemophilia A.

  5. The head that wears the crown: Henry VIII and traumatic brain injury.

    Science.gov (United States)

    Ikram, Muhammad Qaiser; Sajjad, Fazle Hakim; Salardini, Arash

    2016-06-01

    Henry VIII of England is one of the most controversial figures in European history. He was born on 28 June 1491 as the second son of Henry VII and Elizabeth of York and became the heir to the English throne after his elder brother died prematurely. A contradictory picture of Henry's character emerges from history: the young Henry was a vigorous, generous and intelligent king who saw early military and naval successes. In contrast, in his later years he became cruel, petty and tyrannical. His political paranoia and military misjudgements are in direct contrast to his earlier successes and promise. Several hypotheses have been put forward regarding his transformation from a renaissance king to a later medieval tyrant, including endocrinopathies, psychiatric illnesses and traumatic brain injury. In this paper we examine the historical evidence linking the change in Henry's personality and health problems to traumatic brain injury. To our knowledge this is the first systematic neurological study of traumatic brain injury in Henry VIII. Copyright © 2015 Elsevier Ltd. All rights reserved.

  6. Detection of Fibrinogen and Coagulation Factor VIII in Plasma by a Quartz Crystal Microbalance Biosensor

    Directory of Open Access Journals (Sweden)

    Chunyan Yao

    2013-05-01

    Full Text Available A quartz crystal microbalance (QCM biosensor with nanogram sensitivity has been constructed through a reasonable designing and biological processing of the piezoelectric quartz crystals. Due to its highly sensitivity, real time detection and low cost, the proposed QCM biosensor has a promising potential in blood coagulation research. In the current study, the QCM biosensor was used to determine the activated partial thromboplastin time (APTT for 120 anticoagulated plasma specimens. A good linear relationship was found in a double-logarithmic plot of APTT versus fibrinogen concentration in the range of 1.58–6.30 g/L. For factor VIII, the detection range by the QCM biosensor is 0.0185–0.111 mg/L. The QCM biosensor results were compared with those obtained by commercial optical coagulometry and a good agreement (correlation coefficient is 0.949 for fibrinogen, and 0.948 for factor VIII was reached. Furthermore, the QCM determination can be completed within 10 min. Our study suggested that the proposed QCM biosensor could provide for more convenient and time saving operations, which may be useful in clinical situations for rapid monitoring of anticoagulant therapy using small volume (20 μL plasma specimens.

  7. Improving attitudes toward mathematics learning with problem posing in class VIII

    Science.gov (United States)

    Vionita, Alfha; Purboningsih, Dyah

    2017-08-01

    This research is classroom action research which is collaborated to improve student's behavior toward math and mathematics learning at class VIII by using problem posing approach. The subject of research is all of students grade VIIIA which consist of 32 students. This research has been held on two period, first period is about 3 times meeting, and second period is about 4 times meeting. The instrument of this research is implementation of learning observation's guidance by using problem posing approach. Cycle test has been used to measure cognitive competence, and questionnaire to measure the students' behavior in mathematics learning process. The result of research shows the students' behavior has been improving after using problem posing approach. It is showed by the behavior's criteria of students that has increasing result from the average in first period to high in second period. Furthermore, the percentage of test result is also improve from 68,75% in first period to 78,13% in second period. On the other hand, the implementation of learning observation by using problem posing approach has also improving and it is showed by the average percentage of teacher's achievement in first period is 89,2% and student's achievement 85,8%. These results get increase in second period for both teacher and students' achievement which are 94,4% and 91,11%. As a result, students' behavior toward math learning process in class VIII has been improving by using problem posing approach.

  8. Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A

    Science.gov (United States)

    Sherman, Alexandra; Biswas, Moanaro; Herzog, Roland W.

    2017-01-01

    Hemophilia A (coagulation factor VIII deficiency) is a debilitating genetic disorder that is primarily treated with intravenous replacement therapy. Despite a variety of factor VIII protein formulations available, the risk of developing anti-dug antibodies (“inhibitors”) remains. Overall, 20–30% of patients with severe disease develop inhibitors. Current clinical immune tolerance induction protocols to eliminate inhibitors are not effective in all patients, and there are no prophylactic protocols to prevent the immune response. New experimental therapies, such as gene and cell therapies, show promising results in pre-clinical studies in animal models of hemophilia. Examples include hepatic gene transfer with viral vectors, genetically engineered regulatory T cells (Treg), in vivo Treg induction using immune modulatory drugs, and maternal antigen transfer. Furthermore, an oral tolerance protocol is being developed based on transgenic lettuce plants, which suppressed inhibitor formation in hemophilic mice and dogs. Hopefully, some of these innovative approaches will reduce the risk of and/or more effectively eliminate inhibitor formation in future treatment of hemophilia A. PMID:29225598

  9. A new recombinant factor VIII: from genetics to clinical use

    Directory of Open Access Journals (Sweden)

    Santagostino E

    2014-12-01

    Full Text Available Elena Santagostino Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan, Italy Abstract: Advances in recombinant technology and knowledge about coagulation factor VIII (FVIII are building a platform for new therapeutic options in patients with hemophilia A. The development of turoctocog alfa, a novel, high-purity, third-generation, B-domain truncated recombinant FVIII, has been produced and formulated without the use of animal-derived or human serum-derived components, in the wake of understanding of the new biochemical characteristics of FVIII, namely its protein structure, and glycosylation and sulfating patterns. Culture conditions and a five-step purification process have been developed to optimize the safety of turoctocog alfa. The results of two pilot clinical trials using turoctocog alfa confirmed high safety levels, with no patient developing inhibitors during the period of observation. The purpose of this review is to describe briefly the molecular and biological properties of turoctocog alfa, together with details of its clinical development, with emphasis on the needs of patients with hemophilia A. Keywords: hemophilia A, recombinant factor VIII, turoctocog alfa, purification, inhibitor, safety

  10. KEANEKARAGAMAN HYMENOPTERA PARASITOID PADA PERKEBUNAN KELAPA SAWIT PTPN VIII CINDALI, BOGOR

    Directory of Open Access Journals (Sweden)

    Ichsan Luqmana Indra Putra

    2016-09-01

    Full Text Available Diversity of parasitic Hymenoptera in PTPN VIII oil palm plantation Cindali, Bogor. One group of important natural enemies in oil palm plantation is parasitic Hymenoptera. The purpose of this research is to know the diversity and fluctuation of parasitic Hymenoptera PTPN VIII Cindali oil palm plantation. This research was conducted in 6 blocks of oil palm in September 2014 – June 2015. There were 5 plots in every observation blocks 39.2 x 39.2 m in size, and used direct and indirect method. Direct method done by 5 plants in every plots was taken randomized to observed and taken the herbivore insects to reared until the parasitic Hymenoptera came out. Observation of cover crops conducted by 3 subplots determined diagonally in every plots 9.8 x 9.8 m in size and herbivore insects was observed and collected. Indirect methods used sweep net and yellow pan trap. The result of this research, 26 parasitic Hymenoptera families was found, with the Braconidae was the most morphospecies found and the most individual amount was Scelionidae. The abundance of parasitoid in every month fluctuated.

  11. PENGARUH KONSELING KELOMPOK TERHADAP KONFORMITAS SISWI KELAS VIII SMPIT BINA AMAL SEMARANG

    Directory of Open Access Journals (Sweden)

    sudyastuti sudyastuti

    2017-03-01

    Full Text Available This research was conducted based on the phenomenon that happens to grade VIII SMPIT Bina Amal Semarang which has the social conformity low. The purpose of this research is to proof  the influence of counseling service groups towards the conformity. The type of this research is experimental research. The research was conducted with seven times the grant of preferential treatment on grade VIII SMPIT Bina Amal Semarang, research subject with 8 students. The data collection method used is the psychology scale. Data analysis techniques using deskriptif analysis of percentage and wilcoxon test. The results showed incoming students conformity category is middle (59,75%. After being given the treatment through the counseling of the group, a significant unchanged in conformity of students. Conformity of the students in a middle category (60,37%. It shows that conformity of student can’t be influenced through the counseling service groups. Conformity of students not depend on one cause but the another thing to establish it as cohesion,the pretension to change, and the environmental support.

  12. PROSES BERPIKIR SISWA KELAS VIII DALAM MENYELESAIKAN SOAL MATEMATIKA TIMSS MATERI BESAR SUDUT DALAM BENTUK GEOMETRIS

    Directory of Open Access Journals (Sweden)

    Nurul Hidayati Arifani

    2017-07-01

    Full Text Available This study aims to describe the students' thinking process in solving TIMSS math problem on measurement of angle in geometric shapes based on Polya’s problem solving step associated with Swartz’s thinking process theory. The subject of the research was a grade VIII student in SMP Negeri 4 Malang who was classified as intelligent but made many mistakes when completing the test. Data collection methods used were test and interview methods. The results show that students go through the step of generating ideas, clarifying ideas, assessing the reasonableness of ideas, and thinking complex on every step of problem solving, but at the look back step, students do not clarify the idea. Penelitian ini bertujuan untuk mendeskripsikan proses berpikir siswa dalam menyelesaikan soal matematika TIMSS materi besar sudut dalam bentuk geometris berdasarkan langkah penyelesaian masalah Polya yang dikaitkan dengan teori proses berpikir Swartz. Subjek penelitian adalah seorang siswa kelas VIII di SMP Negeri 4 Malang yang tergolong pandai, tetapi banyak melakukan kesalahan saat menyelesaikan soal tes. Metode pengumpulan data yang digunakan adalah metode tes dan wawancara. Hasil penelitian menunjukkan bahwa siswa dalam menyelesaikan soal TIMSS melalui tahap menghasilkan ide, mengklarifikasi ide, menilai kelayakan ide, dan berpikir kompleks pada setiap langkah penyelesaian masalah. Namun, pada tahap memeriksa kembali, siswa tidak melakukan pengklarifikasian ide.

  13. Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels.

    Science.gov (United States)

    Alami, Meriem; Vacher, Hélène; Bosmans, Frank; Devaux, Christiane; Rosso, Jean-Pierre; Bougis, Pierre E; Tytgat, Jan; Darbon, Hervé; Martin-Eauclaire, Marie-France

    2003-11-01

    The venom of the scorpion Androctonus mauretanicus mauretanicus was screened by use of a specific serum directed against AaH II, the scorpion alpha-toxin of reference, with the aim of identifying new analogues. This led to the isolation of Amm VIII (7382.57 Da), which gave a highly positive response in ELISA, but was totally devoid of toxicity when injected subcutaneously into mice. In voltage-clamp experiments with rat brain type II Na+ channel rNa(v)1.2 or rat skeletal muscle Na+ channel rNa(v)1.4, expressed in Xenopus oocytes, the EC50 values of the toxin-induced slowing of inactivation were: 29+/-5 and 416+/-14 nM respectively for AmmVIII and 2.6+/-0.3 nM and 2.2+/-0.2 nM, respectively, for AaH II interactions. Accordingly, Amm VIII clearly discriminates neuronal versus muscular Na+ channel. The Amm VIII cDNA was amplified from a venom gland cDNA library and its oligonucleotide sequence determined. It shows 87% sequence homology with AaH II, but carries an unusual extension at its C-terminal end, consisting of an additional Asp due to a point mutation in the cDNA penultimate codon. We hypothesized that this extra amino acid residue could induce steric hindrance and dramatically reduce recognition of the target by Amm VIII. We constructed a model of Amm VIII based on the X-ray structure of AaH II to clarify this point. Molecular modelling showed that this C-terminal extension does not lead to an overall conformational change in Amm VIII, but drastically modifies the charge repartition and, consequently, the electrostatic dipole moment of the molecule. At last, liquid-phase radioimmunassays with poly- and monoclonal anti-(AaH II) antibodies showed the loss of conformational epitopes between AaH II and Amm VIII.

  14. Evaluation of B&W UO2/ThO2 VIII experimental core: criticality and thermal disadvantage factor analysis

    Energy Technology Data Exchange (ETDEWEB)

    Carlo Parisi; Emanuele Negrenti

    2017-02-01

    In the framework of the OECD/NEA International Reactor Physics Experiment (IRPHE) Project, an evaluation of core VIII of the Babcock & Wilcox (B&W) Spectral Shift Control Reactor (SSCR) critical experiment program was performed. The SSCR concept, moderated and cooled by a variable mixture of heavy and light water, envisaged changing of the thermal neutron spectrum during the operation to encourage breeding and to sustain the core criticality. Core VIII contained 2188 fuel rods with 93% enriched UO2-ThO2 fuel in a moderator mixture of heavy and light water. The criticality experiment and measurements of the thermal disadvantage factor were evaluated.

  15. Species - San Diego Co. [ds121

    Data.gov (United States)

    California Department of Resources — This is the Biological Observation Database point layer representing baseline observations of sensitive species (as defined by the MSCP) throughout San Diego County....

  16. 78 FR 18238 - Safety Zone; SFPD Training Safety Zone; San Francisco Bay, San Francisco, CA

    Science.gov (United States)

    2013-03-26

    ... William Hawn, U.S. Coast Guard Sector San Francisco; telephone (415) 399-7442 or email at D11-PF-Marine... navigable waters around the SFPD's maritime interdiction training exercises. The SFPD Training Safety ] Zone... Hunters Point in San Francisco, CA in support of the San Francisco Police Department's maritime...

  17. 77 FR 34988 - Notice of Inventory Completion: San Diego State University, San Diego, CA

    Science.gov (United States)

    2012-06-12

    ... National Park Service Notice of Inventory Completion: San Diego State University, San Diego, CA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: San Diego State University Archeology Collections Management Program has completed an inventory of human remains and associated funerary objects, in...

  18. 77 FR 46115 - Notice of Inventory Completion: San Diego Museum of Man, San Diego, CA

    Science.gov (United States)

    2012-08-02

    ...-1100-665] Notice of Inventory Completion: San Diego Museum of Man, San Diego, CA AGENCY: National Park Service, Interior. ACTION: Notice. SUMMARY: The San Diego Museum of Man has completed an inventory of... Diego Museum of Man. Repatriation of the human remains to the Indian tribe stated below may occur if no...

  19. 78 FR 34123 - Notice of Inventory Completion: San Francisco State University NAGPRA Program, San Francisco, CA

    Science.gov (United States)

    2013-06-06

    ... NAGPRA Program, c/o Department of Anthropology, San Francisco State University, 1600 Holloway Avenue, San... construction activities for the Middle Fork American River Project. Site materials from the Middle Fork... Jeffrey Boland Fentress, San Francisco State University NAGPRA Program, c/o Department of Anthropology...

  20. Cuartel San Carlos. Yacimiento veterano

    Directory of Open Access Journals (Sweden)

    Mariana Flores

    2007-01-01

    Full Text Available El Cuartel San Carlos es un monumento histórico nacional (1986 de finales del siglo XVIII (1785-1790, caracterizado por sufrir diversas adversidades en su construcción y soportar los terremotos de 1812 y 1900. En el año 2006, el organismo encargado de su custodia, el Instituto de Patrimonio Cultural del Ministerio de Cultura, ejecutó tres etapas de exploración arqueológica, que abarcaron las áreas Traspatio, Patio Central y las Naves Este y Oeste de la edificación. Este trabajo reseña el análisis de la documentación arqueológica obtenida en el sitio, a partir de la realización de dicho proyecto, denominado EACUSAC (Estudio Arqueológico del Cuartel San Carlos, que representa además, la tercera campaña realizada en el sitio. La importancia de este yacimiento histórico, radica en su participación en los acontecimientos que propiciaron conflictos de poder durante el surgimiento de la República y en los sucesos políticos del siglo XX. De igual manera, se encontró en el sitio una amplia muestra de materiales arqueológicos que reseñan un estilo de vida cotidiana militar, así como las dinámicas sociales internas ocurridas en el San Carlos, como lugar estratégico para la defensa de los diferentes regímenes que atravesó el país, desde la época del imperialismo español hasta nuestros días.

  1. A lenda de Pedro Sem: da oralidade à poesia romântica, ao cordel (português e brasileiro) e à literatura para crianças e jovens

    OpenAIRE

    Nogueira, Carlos

    2008-01-01

    Neste ensaio, abordamos a lenda de Pedro Cem a partir das diversas versões que conhecemos, orais e escritas, eruditas e populares, procurando determinar o significado desse diálogo e a estrutura profunda de cada texto. This essay analyses the meaning and structure of the different versions –oral, written, learned and popular– of the legend of Pedro Cem

  2. Aproximación a la vida y obra del pintor y estofador alcalaíno-granadino Pedro Raxis

    Directory of Open Access Journals (Sweden)

    Gila Medina, Lázaro

    2003-12-01

    Full Text Available This article offers an approximation to the life and work of Pedro de Raxis, a key artist in Counter Reformation Granada. Raxis was the nephew of the sculptor Pablo de Rojas, who was also the master of Juan Martinez Montañés. All three were from Alcalá de Henares and pioneers in the stylistic transition from the Roman Renaissance to early Baroque naturalism. Raxis also established an extremely active studio, precursor in the formation of famous artists, and during his lifetime was considered to be the "father" of the estofa technique (the sizing, gilding and painting of wooden statuary, although his facet as a painter was underestimated.

    En el presente trabajo realizamos una aproximación a la vida y la obra de un artista clave para la Granada de la Contrarreforma: Pedro de Raxis, sobrino carnal del escultor Pablo de Rojas -maestro a su vez del también alcalaíno Juan Martínez Montañés-, todos ellos figuras pioneras al enmarcar el paso del renacimiento romanista al primer naturalismo barroco. Creador, igualmente, de un activísimo taller, precursor en la formación de renombrados artistas, fue considerado en su época como el "padre de la estofa", aunque se infravaloró su faceta de pintor.

  3. DE PAULO LEMINSKI A PEDRO ANTÔNIO GABRIEL: DIÁLOGOS ATEMPORAIS NA LITERATURA BRASILEIRA CONTEMPORÂNEA

    Directory of Open Access Journals (Sweden)

    Jennifer da Silva Gramiani Celeste (CES/JF

    2017-05-01

    Full Text Available

    O presente artigo objetiva estabelecer diálogo entre poemas da autoria de Paulo Leminski e Pedro Antônio Gabriel. Os estudos relativos à Cibercultura, à Literatura e à Modernidade serão os norteadores deste trabalho. A realização deste estudo é justificada com base na relevância em compreender os diálogos contemplados pela Literatura Brasileira Contemporânea; ademais, a dinâmica que demarca a atual produção poética no Brasil, influenciada pelo advento da internet. É possível afirmar que os autores dialogam entre si, seja via jogos de natureza sonora ou visual, seja via temáticas contempladas. As conversas são atemporais, pois transcendem crenças e perspectivas inerentes a uma dada época.

    Palavras-chave: Poesia. Literatura Brasileira Contemporânea. Paulo Leminski. Pedro Antônio Gabriel.

  4. También la interpretación es un collage: conjeturas en torno a Pedro Manrique Figueroa

    Directory of Open Access Journals (Sweden)

    Jerónimo Duarte Riascos

    2010-06-01

    Full Text Available Pedro Manrique Figueroa es un personaje central en la historia del arte colombiano. De su vida y obra no quedan más que huellas, y es quizás por esta razón que su existencia se encuentra a medio camino entra la realidad y la ficción. Este texto, tras realizar un recuento de la génesis del personaje, pretende contribuir al análisis sobre Manrique desde dos puntos de vista diferentes. El primero tratará de aproximarse al gesto de su creación desde la noción de autor de Foucault y las particularidades del juego según Huizinga y Caillois. El segundo hará lo propio con el personaje para analizar su performancia.Pedro Manrique Figueroa is a pivotal figure in Colombian art history. All that is left from his life and work are memories, perhaps that is the reason why his existence swirls around reality and fiction. This article, after briefly describing the character’s genesis, aims to analyze Manrique from two different points of view. The first one will try to examine the act of creation with the tools provided by the theories of Foucault, Huizinga and Caillois. The second one, will approach the character to study its performative qualities.

  5. Algunas notas sobre la proyección literaria en el epistolario de Pedro Salinas a Katherine Whitmore

    Directory of Open Access Journals (Sweden)

    Peragón López, Clara Eugenia

    2004-12-01

    Full Text Available Pedro Salinas' lover with no name that appears in his trilogy in loving poetry (La voz a ti debida. Razón de amor, Largo lament is presented with her own name in the group of letters sent by the poet to Katherine Whitmore. Through the analysis of these fascinating texts we will be able to establish tight relationship between his real world and his poetic world. Their content will reveal us a double documental and literary aspect of one of the best poems of love of the XX century.La amada innombrada en la trilogía de poesía amorosa de Pedro Salinas (La voz a ti debida. Razón de amor, Largo lamento se presenta con nombre propio en el conjunto de cartas enviadas por el poeta a Katherine Whitmore. A través del análisis de este fascinante epistolario podremos establecer una estrecha relación entre el mundo real y el mundo poético saliniano. Su contenido nos revelará un doble aspecto documental y literario y nos acercará a uno de los mejores poemarios de temática amorosa del siglo XX.

  6. Conocimiento de la atención del paro cardiorrespiratorio en médicos del Hospital Pedro de Bethancourt

    Directory of Open Access Journals (Sweden)

    Henry Samayoa

    2017-03-01

    Full Text Available El paro cardiorrespiratorio (PCR es el cese de la respiración y el latido cardiaco en una persona. Las maniobras de reanimación cardiopulmonar (RCP son el conjunto de maniobras que se realizan con la finalidad de sustituir y restaurar la circulación y respiración espontánea en un paciente en PCR. El objetivo fue evaluar el conocimiento de la atención del PCR según Guías AHA 2010 en los médicos que laboran durante el año 2014 en el Hospital Pedro de Bethancourt de la Antigua Guatemala. Se realizó un estudio descriptivo comparativo. Para evaluar el conocimiento de la atención del PCR entre los médicos jefes (especialistas y médicos residentes, se utilizó un cuestionario de 30 preguntas sobre conocimientos de soporte vital básico y avanzado. Se logró la participación de 104 médicos. El promedio de calificación fue de 33 puntos para los Médicos Jefes y de 23 puntos para los Médicos Residentes. Los médicos que laboran en el Hospital Pedro de Bethancourt no tienen el conocimiento óptimo de la atención del PCR avanzado según las Guías de la AHA 2010.

  7. La imagen de D. Pedro y D. Miguel en la novela histórica portuguesa del siglo XIX

    Directory of Open Access Journals (Sweden)

    Beatriz Peralta García

    2005-01-01

    Full Text Available La revolución liberal en Portugal tuvo su reflejo en la literatura de la segunda mitad del siglo xix. La novela histórica de actualidad aborda los acontecimientos políticos más importantes con el objetivo de consolidar el nuevo estado liberal tras los enfrentamientos con los absolutistas. La imagen que de los infantes D. Pedro, liberal, y D. Miguel, absolutista, se difunde, caracteriza con éxito a ambos personajes, creando un estereotipo que se mantiene hasta la actualidad. El objetivo del trabajo es analizar los diferentes procesos que se utilizan para la identificación de esta figuras así como su trasfondo político.The liberal revolution in Portugal had his reflex in the literature of the second half of the xixth century. The historical novel of current importance approaches the most important political events with the aim(lens to consolidate the new liberal condition(state after the clashes with the absolutists. The image that of the infantes D. Pedro, liberal, and D. Michael, absolutist, spreads, characterizes successfully both prominent figures, creating a stereotype that is kept up to the current importance. The aim(lens of the work is to analyze the different processes that are in use for the identification of this one you appear as well as his political background.

  8. Pedro Poveda en clave historiográfica: un debate cultural y pedagógico del siglo XX

    Directory of Open Access Journals (Sweden)

    Pego Puigbó, Armando

    2007-12-01

    Full Text Available In this paper a view on the historiographic reception of the life and works of the priest and pedagogue Pedro Poveda (1874-1936 is tried to offer. The characteristic features of his catholic pedagogical proposal are showed in the context of a secularized age. Poveda looked forward to making the Christian message present into the educational structures of the State through a dialogue between faith and science. This program for modernization implies the hermeneutic tools of a period marked by the activities of the ILE.En este artículo se procura ofrecer una panorámica de la recepción historiográfica de la vida y la obra del sacerdote y pedagogo Pedro Poveda (1874-1936. Se presentan así los rasgos de una singular propuesta pedagógica católica en una época secularizada. Poveda quiso hacer presente el mensaje cristiano en las estructuras educativas estatales animando el diálogo entre fe y ciencia. Este programa de modernización comprende también las claves hermenéuticas de una época marcada por las actividades de la ILE.

  9. Mapping and analysis of the assignment concepts process at academic secretaries of Colegio Pedro II: reflections and proposals for improvement

    Directory of Open Access Journals (Sweden)

    Patrícia Bitencourt de Carvalho Athaydes

    2016-12-01

    Full Text Available The Colegio Pedro II was equated to Federal Institutes of Education, Science and Technology by Law 12677 Publication of June 25, 2012. If, on the one hand, this equalization resulted in an expressive organizational restructuring, with growth of the number of educational units, in addition to the incorporation of new educational levels, on the other, this institutional growth was dissociated from efforts of standardization of administrative processes, notably, under the academic departments of different units – where it shows a variation of the process of launching notes/concepts. In order to contribute with improvements to the operation of the institution, the present article aims to map and analyse comparatively the launch process of notes/concepts in three campus of the Colegio Pedro II. Methodologically, are held in-person interviews with professionals responsible for the academic departments of the following units, Engenho Novo I, Humaita I and Realengo I, in order to obtain the necessary subsidies to support the design of the processes performed by these academic departments units. As a result, it can be verified that the processes of the academic departments are not aligned to any system of performance indicators, which motivated the proposal of a standard process for the launching of notes/concepts, as well as a performance indicators panel (KPIs.

  10. The scorpion toxin Amm VIII induces pain hypersensitivity through gain-of-function of TTX-sensitive Na⁺ channels.

    Science.gov (United States)

    Abbas, Najwa; Gaudioso-Tyzra, Christelle; Bonnet, Caroline; Gabriac, Mélanie; Amsalem, Muriel; Lonigro, Aurélie; Padilla, Françoise; Crest, Marcel; Martin-Eauclaire, Marie-France; Delmas, Patrick

    2013-08-01

    Voltage-gated Na(+) channels (Nav) are the targets of a variety of scorpion toxins. Here, we investigated the effects of Amm VIII, a toxin isolated from the venom of the scorpion Androctonus mauretanicus mauretanicus, on pain-related behaviours in mice. The effects of Amm VIII were compared with the classic scorpion α-toxin AaH II from Androctonus australis. Contrary to AaH II, intraplantar injection of Amm VIII at relatively high concentrations caused little nocifensive behaviours. However, Amm VIII induced rapid mechanical and thermal pain hypersensitivities. We evaluated the toxins' effects on Nav currents in nociceptive dorsal root ganglion (DRG) neurons and immortalized DRG neuron-derived F11 cells. Amm VIII and AaH II enhanced tetrodotoxin-sensitive (TTX-S) Nav currents in DRG and F11 cells. Both toxins impaired fast inactivation and negatively shifted activation. AaH II was more potent than Amm VIII at modulating TTX-S Nav currents with EC50 of 5 nM and 1 μM, respectively. AaH II and Amm VIII also impaired fast inactivation of Nav1.7, with EC50 of 6.8 nM and 1.76 μM, respectively. Neither Nav1.8 nor Nav1.9 was affected by the toxins. AaH II and Amm VIII reduced first spike latency and lowered action potential threshold. Amm VIII was less efficient than AaH II in increasing the gain of the firing frequency-stimulation relationship. In conclusion, our data show that Amm VIII, although less potent than AaH II, acts as a gating-modifier peptide reminiscent of classic α-toxins, and suggest that its hyperalgesic effects can be ascribed to gain-of-function of TTX-S Na(+) channels in nociceptors. Copyright © 2013 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.

  11. Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen-deuterium exchange mass spectrometry

    Science.gov (United States)

    Sevy, Alexander M.; Healey, John F.; Deng, Wei; Spiegel, P. Clint; Meeks, Shannon L.; Li, Renhao

    2014-01-01

    Summary Background The development of anti-factor VIII (fVIII) antibodies (inhibitors) is a significant complication in the management of patients with hemophilia A, leading to significant increases in morbidity and treatment cost. Using a panel of anti-fVIII monoclonal antibodies (MAbs) to different epitopes on fVIII, we recently have shown that epitope specificity, inhibitor kinetics, and time to maximum inhibition are more important than inhibitor titer in predicting response to fVIII and the combination of fVIII and recombinant factor VIIa. In particular, a subset of high-titer inhibitors responded to high dose fVIII, which would not be predicted based on their inhibitor titer alone. Thus the ability to quickly map the epitope spectrum of patient plasma using a clinically feasible assay may fundamentally change how clinicians approach the treatment of high-titer inhibitor patients. Objectives To map the epitopes of anti-fVIII MAbs, of which 3 are classical inhibitors and one non-classical, using hydrogen-deuterium exchange coupled with liquid chromatography-mass spectrometry (HDX-MS). Methods Binding epitopes of 4 MAbs targeting fVIII C2 domain were mapped using HDX-MS. Results The epitopes determined by HDX-MS are consistent with those obtained earlier through structural characterization and antibody competition assays. In addition classical and non-classical inhibitor epitopes could be distinguished using a limited subset of C2-derived peptic fragments. Conclusion Our results demonstrate the effectiveness and robustness of the HDX-MS method for epitope mapping and suggest a potential role of rapid mapping of fVIII inhibitor epitopes in facilitating individualized treatment of inhibitor patients. PMID:24152306

  12. San Diego's High School Dropout Crisis

    Science.gov (United States)

    Wilson, James C.

    2012-01-01

    This article highlights San Diego's dropout problem and how much it's costing the city and the state. Most San Diegans do not realize the enormous impact high school dropouts on their city. The California Dropout Research Project, located at the University of California at Santa Barbara, has estimated the lifetime cost of one class or cohort of…

  13. Keefektifan Experiential Learning Berbantuan Origami Terhadap Kemampuan Keruangan Siswa Kelas VIII

    Directory of Open Access Journals (Sweden)

    Isnaeni Umi Machromah

    2014-11-01

    Full Text Available AbstrakPenelitian eksperimen ini bertujuan untuk mengetahui keefektifan pembelajaran Experiential Learning berbantuan origami terhadap kemampuan keruangan siswa dengan kualifikasi keefektifan yang telah ditentukan. Populasi yaitu siswa kelas VIII SMP Negeri 3 Colomadu tahun pelajaran 2012/2013. Sampel diambil secara simple random sampling. Hasil penelitian ini yaitu: (1 Uji proporsi ketuntasan belajar menunjukkan siswa kelompok eksperimen telah mencapai ketuntasan belajar; (2 Uji perbedaan dua rata-rata menghasilkan simpulan bahwa rata-rata hasil post-test kemam-puan keruangan siswa kelompok eksperimen lebih dari kelompok kontrol; (3 Analisis re-gresi menunjukkan bahwa motivasi belajar siswa memberikan pengaruh positif sebesar 49,3% terhadap kemampuan keruangan siswa; (4 Uji gain ternormalisasi menunjukkan terdapat peningkatan kemampuan keruangan siswa secara signifikan pada kategaori sedang untuk kelompok eksperimen dan kategori rendah untuk kelompok kontrol. Simpulan yang diperoleh yaitu Experiential Learning berbantuan origami efektif terhadap kemampuan keruangan siswa kelas VIII. AbstractThis experiment research aims to determine the effectiveness of Experiential Learning with Origami to the students’s spatial abilities by the criteria of effectiveness. The population of this research is students of grade VIII of SMP Negeri 3 Colomadu 2012/2013 academic year. Independent variables used in this research are learning by Experiential Learning with origami and student’s motivation. While the dependent variable is the student’s spatial abilities. This research is using documentation, spatial abilities’s test, dan motivation’s scale for collecting data method. Result of this research are: (1 proportion test show that the experiment group has reached mastering of learning clasically and personally; (2 result of spatial ablities’s post test in experiment group better than control group; (3 result of regretion shows that student

  14. Analysis of factor VIII gene inversions in 164 unrelated hemophilia A families

    Energy Technology Data Exchange (ETDEWEB)

    Vnencak-Jones, L.; Phillips, J.A. III; Janco, R.L. [Vanderbilt Univ. School of Medicine, Nashville, TN (United States)] [and others

    1994-09-01

    Hemophilia A is an X-linked recessive disease with variable phenotype and both heterogeneous and wide spread mutations in the factor VIII (F8) gene. As a result, diagnostic carrier or prenatal testing often relies upon laborious DNA linkage analysis. Recently, inversion mutations resulting from an intrachromosomal recombination between DNA sequences in one of two A genes {approximately}500 kb upstream from the F8 gene and a homologous A gene in intron 22 of the F8 gene were identified and found in 45% of severe hemophiliacs. We have analyzed banked DNA collected since 1986 from affected males or obligate carrier females representing 164 unrelated hemophilia A families. The disease was sporadic in 37%, familial in 54% and in 10% of families incomplete information was given. A unique deletion was identified in 1/164, a normal pattern was observed in 110/164 (67%), and 53/164 (32%) families had inversion mutations with 43/53 (81%) involving the distal A gene (R3 pattern) and 10/53 (19%) involving the proximal A gene (R2 pattern). While 19% of all rearrangements were R2, in 35 families with severe disease (< 1% VIII:C activity) all 16 rearrangements seen were R3. In 18 families with the R3 pattern and known activities, 16 (89%) had levels < 1%, with the remaining 2 families having {le} 2.4% activity. Further, 18 referrals specifically noted the production of inhibitors and 8/18 (45%) had the R3 pattern. Our findings demonstrate that the R3 inversion mutation patterns is (1) only seen with VIII:C activity levels of {le} 2.4%, (2) seen in 46% of families with severe hemophilia, (3) seen in 45% of hemophiliacs known to have inhibitors, (4) not correlated with sporadic or familial disease and (5) not in disequilibrium with the Bcl I or Taq I intron 18 or ST14 polymorphisms. Finally, in families positive for an inversion mutation, direct testing offers a highly accurate and less expensive alternative to DNA linkage analysis.

  15. Hemophilia A gene therapy via intraosseous delivery of factor VIII-lentiviral vectors.

    Science.gov (United States)

    Miao, Carol H

    2016-01-01

    Current treatment of hemophilia A (HemA) patients with repeated infusions of factor VIII (FVIII; abbreviated as F8 in constructs) is costly, inconvenient, and incompletely effective. In addition, approximately 25 % of treated patients develop anti-factor VIII immune responses. Gene therapy that can achieve long-term phenotypic correction without the complication of anti-factor VIII antibody formation is highly desired. Lentiviral vector (LV)-mediated gene transfer into hematopoietic stem cells (HSCs) results in stable integration of FVIII gene into the host genome, leading to persistent therapeutic effect. However, ex vivo HSC gene therapy requires pre-conditioning which is highly undesirable for hemophilia patients. The recently developed novel methodology of direct intraosseous (IO) delivery of LVs can efficiently transduce bone marrow cells, generating high levels of transgene expression in HSCs. IO delivery of E-F8-LV utilizing a ubiquitous EF1α promoter generated initially therapeutic levels of FVIII, however, robust anti-FVIII antibody responses ensued neutralized functional FVIII activity in the circulation. In contrast, a single IO delivery of G-FVIII-LV utilizing a megakaryocytic-specific GP1bα promoter achieved platelet-specific FVIII expression, leading to persistent, partial correction of HemA in treated animals. Most interestingly, comparable therapeutic benefit with G-F8-LV was obtained in HemA mice with pre-existing anti-FVIII inhibitors. Platelets is an ideal IO delivery vehicle since FVIII stored in α-granules of platelets is protected from high-titer anti-FVIII antibodies; and that even relatively small numbers of activated platelets that locally excrete FVIII may be sufficient to promote efficient clot formation during bleeding. Additionally, combination of pharmacological agents improved transduction of LVs and persistence of transduced cells and transgene expression. Overall, a single IO infusion of G-F8-LV can generate long-term stable

  16. Storage of factor VIII variants with impaired von Willebrand factor binding in Weibel-Palade bodies in endothelial cells

    NARCIS (Netherlands)

    van den Biggelaar, Maartje; Bouwens, Eveline A. M.; Voorberg, Jan; Mertens, Koen

    2011-01-01

    Point mutations resulting in reduced factor VIII (FVIII) binding to von Willebrand factor (VWF) are an important cause of mild/moderate hemophilia A. Treatment includes desmopressin infusion, which concomitantly increases VWF and FVIII plasma levels, apparently from storage pools containing both

  17. Requirements for cellular co-trafficking of factor VIII and von Willebrand factor to Weibel-Palade bodies

    NARCIS (Netherlands)

    van den Biggelaar, M.; Bierings, R.; Storm, G.; Voorberg, J.; Mertens, K.

    2007-01-01

    von Willebrand factor (VWF) serves a critical role as a carrier of factor (F)VIII in circulation. While it is generally believed that FVIII and VWF assemble in circulation after secretion from different cells, an alternative view is that cells should exist that co-express FVIII and VWF. In this

  18. Effectiveness of Peer Tutoring in Learning English among Tutors and Tutees of Class VIII Students in Kancheepuram DT

    Science.gov (United States)

    Marieswari, M.; Prema, N.

    2016-01-01

    The peer who teaches to their mates is peer tutoring. It is a common instructional strategy used in classrooms. The aim of this study is to know whether there is any improvement in achievement marks of tutors and tutees after the process of peer tutoring. Class VIII students were selected as the sample for the present experimental study. The…

  19. Evaluation of the biological differences of canine and human factor VIII in gene delivery: Implications in human hemophilia treatment

    Science.gov (United States)

    The canine is the most important large animal model for testing novel hemophilia A(HA) treatment. It is often necessary to use canine factor VIII (cFIII) gene or protein for the evaluation of HA treatment in the canine model. However, the different biological properties between cFVIII and human FVII...

  20. Mediastinal, subcutaneous and multiple muscular abscesses caused by group B streptococcus serotype VIII in a type 2 diabetes mellitus patient.

    Science.gov (United States)

    Omura, Yuka; Kusama, Yoshiki; Takeuchi, Noriko; Ishiwada, Naruhiko

    2018-01-17

    We report a case of mediastinal subcutaneous and multiple muscular abscesses caused by group B streptococcus serotype VIII in a type 2 diabetes mellitus patient. The patient arrived at the hospital with the chief complaint of immobility, and blood examination results suggested an acute infection and poorly controlled diabetes mellitus. Group B streptococcal bacteria were cultured from the patient's blood, and identified as serotype VIII upon further analysis. The patient recovered without any sequelae after percutaneous drainage, antibiotic therapy, and intensive glycemic control. Although the incidence of group B streptococcal infection in non-pregnant adults has recently increased in many developed countries, information on serotype VIII infection is quite limited. The reason is that serotype VIII group B streptococci are a Japan-specific serotype, and rarely cause invasive infections, even in Japan. Therefore, further surveillance and case reports should be documented in the future. Copyright © 2017 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  1. Factor VIII genotype and inhibitor development in patients with haemophilia A: highest risk in patients with splice site mutations.

    NARCIS (Netherlands)

    Boekhorst, J.; Lari, G.R.; D'Oiron, R.; Costa, J.M.; Novakova, I.R.O.; Ala, F.A.; Lavergne, J.M.; Heerde, W.L. van

    2008-01-01

    The appearance of inhibitory antibodies against factor VIII (FVIII) is the most severe and costly complication of replacement therapy in patients with haemophilia A (HA). To determine the relationship between FVIII genotype and inhibitor development, baseline FVIII activity, genotype and inhibitor

  2. 77 FR 42696 - Notice of New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108-447)

    Science.gov (United States)

    2012-07-20

    ... Forest Service Notice of New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L... Laws, Recreation Fee Coordinator, 406-283-7648 SUPPLEMENTARY INFORMATION: The Federal Recreation Lands... advance notice in the Federal Register whenever new recreation fee areas are established. This new fee...

  3. 78 FR 19445 - Notice of Proposed New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L...

    Science.gov (United States)

    2013-04-01

    ... Forest Service Notice of Proposed New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII... and maintenance of these recreation sites. Lake Canyon Recreation Area is a fee campground with 54... is to keep the site fees consistent with other campsites in the Lake Canyon Recreation Area. The fee...

  4. 75 FR 2850 - Notice of Proposed New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L...

    Science.gov (United States)

    2010-01-19

    ... Forest Service Notice of Proposed New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII... and recreation experiences. A financial analysis is being completed to determine fee rates. The.... Recreation Passes such as the Northwest Forest Pass would cover day use fees for this trailhead. Northwest...

  5. 76 FR 36518 - Notice of Meeting; Federal Lands Recreation Enhancement Act (Title VIII, Pub. L. 108-447)

    Science.gov (United States)

    2011-06-22

    .... 2. An increase of fees for the Shelf Road Recreation Area in the Royal Gorge Field Office of the BLM..., Bureau of Land Management staff and Committee members. Persons who wish to bring recreation fee matters... Forest Service Notice of Meeting; Federal Lands Recreation Enhancement Act (Title VIII, Pub. L. 108-447...

  6. 75 FR 21583 - Notice of Proposed New Fee Site; Federal Lands Recreation Enhancement Act (Title VIII, Pub. L...

    Science.gov (United States)

    2010-04-26

    ... Forest Service Notice of Proposed New Fee Site; Federal Lands Recreation Enhancement Act (Title VIII, Pub... improve the recreation experience. An analysis of the campground shows that the proposed fees are..., Moab/Monticello Recreation Fee Coordinator, 435-636-3367. Information about proposed fee changes can...

  7. 78 FR 52499 - Notice of New Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108-447)

    Science.gov (United States)

    2013-08-23

    ... Forest Service Notice of New Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108-447) AGENCY: Monongahela National Forest, Forest Service, USDA. ACTION: Notice of new fee site... new recreation fee areas are established. This new fee will be reviewed by the Eastern Region...

  8. 78 FR 41783 - Notice of Proposed New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L...

    Science.gov (United States)

    2013-07-11

    ... Forest Service Notice of Proposed New Fee Sites; Federal Lands Recreation Enhancement Act, (Title VIII... comments can be compiled, analyzed and shared with a Recreation Resource Advisory Committee. New fees would... advance notice in the Federal Register whenever new recreation fee areas are established. Once public...

  9. 75 FR 80789 - Notice of New Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108-447)

    Science.gov (United States)

    2010-12-23

    ... Forest Service Notice of New Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108... Agriculture to publish a six month advance notice in the Federal Register whenever new recreation fee areas are established. This new fee will be reviewed by the Colorado Recreation Resource Advisory Committee...

  10. Chromosome VIII disomy influences the nonsense suppression efficiency and transition metal tolerance of the yeast Saccharomyces cerevisiae.

    Science.gov (United States)

    Zadorsky, S P; Sopova, Y V; Andreichuk, D Y; Startsev, V A; Medvedeva, V P; Inge-Vechtomov, S G

    2015-06-01

    The SUP35 gene of the yeast Saccharomyces cerevisiae encodes the translation termination factor eRF3. Mutations in this gene lead to the suppression of nonsense mutations and a number of other pleiotropic phenotypes, one of which is impaired chromosome segregation during cell division. Similar effects result from replacing the S. cerevisiae SUP35 gene with its orthologues. A number of genetic and epigenetic changes that occur in the sup35 background result in partial compensation for this suppressor effect. In this study we showed that in S. cerevisiae strains in which the SUP35 orthologue from the yeast Pichia methanolica replaces the S. cerevisiae SUP35 gene, chromosome VIII disomy results in decreased efficiency of nonsense suppression. This antisuppressor effect is not associated with decreased stop codon read-through. We identified SBP1, a gene that localizes to chromosome VIII, as a dosage-dependent antisuppressor that strongly contributes to the overall antisuppressor effect of chromosome VIII disomy. Disomy of chromosome VIII also leads to a change in the yeast strains' tolerance of a number of transition metal salts. Copyright © 2015 John Wiley & Sons, Ltd.

  11. 75 FR 5759 - Notice of New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L...

    Science.gov (United States)

    2010-02-04

    ... Forest Service Notice of New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII... Recreation Fee Sites. SUMMARY: The Soda Springs Ranger District of the Caribou-Targhee National Forest is... appreciate and enjoy the availability of developed recreation campground and picnicking facilities. This...

  12. 75 FR 4340 - Notice of New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L...

    Science.gov (United States)

    2010-01-27

    ... Forest Service Notice of New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII.... SUPPLEMENTARY INFORMATION: The Federal Recreation Lands Enhancement Act (Title VII, Pub. L. 108-447) directed... new recreation fee areas are established. The Caribou-Targhee National Forest currently has nine other...

  13. 75 FR 26711 - Notice of New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L...

    Science.gov (United States)

    2010-05-12

    ... No: 2010-11040] DEPARTMENT OF AGRICULTURE Forest Service Notice of New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108-447) AGENCY: National Forests in Mississippi, USDA Forest Service. ACTION: Notice of New Recreation Fee Site. SUMMARY: Bethel Motorcycle and Bethel...

  14. 75 FR 26714 - Notice of Proposed New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII...

    Science.gov (United States)

    2010-05-12

    ... No: 2010-11042] DEPARTMENT OF AGRICULTURE Forest Service Notice of Proposed New Recreation Fee Site; Federal Lands Recreation Enhancement Act, (Title VIII, Pub. L. 108-447) AGENCY: National Forests in Mississippi, USDA Forest Service. ACTION: Notice of Proposed New Recreation Fee Site. SUMMARY: Rattlesnake Bay...

  15. Aproximación a Pedro Laín Entralgo

    Directory of Open Access Journals (Sweden)

    Fernando Sánchez Torres

    2001-12-01

    Full Text Available

    Desde cuando lo descubrí a través de su libro Medicina e historia, quise aproximarme a Pedro Laín Entralgo. Lo hice leyendo sus escritos, que buscaba en las librerías con verdadera avidez.
    Esa fue la aproximación intelectual; la interpersonal la conseguí cuando, en buena hora, el presidente Belisario Betancur lo invitó a Colombia y me relacionó con él en el Palacio de Nariño. Aprovechando tal circunstancia.
    el presidente y yo pensamos que deberíamos llevarlo a la Universidad Nacional a dictar una conferencia, idea que desechamos, habida cuenta de la intolerancia ideológica que imperaba al interior del claustro. Para obviar este inconveniente, encontramos adecuado que su intervención se realizara en un escenario
    apacible, escogido por la Sociedad de Historia de la Medicina. Tuve entonces, como lo tuvieron todos los que acudieron a escucharlo en el Club Médico, el privilegio de oír disertar a uno de los intelectuales más connotados de la España del siglo veinte. El tema: «Relación entre la Medicina y el lenguaje», asunto del cual yo tenía alguna referencia por haber leído su libro La curación por la palabra en la Antigüedad clásica.
    Aquella inolvidable aproximación -digo inolvidable porque por fin lo escuchaba viéndolo en persona ocurrió en el mes de octubre de 1983, el mismo año cuando pasó a ocupar el sillón más encumbrado de la más alta academia de nuestra lengua. Para comentar ese ascenso, escribí en el diario El Tiempo lo siguiente:
    «Analizando el grupo de escritores que en España han llegado a ocupar la categoría de académicos de número en los últimos cincuenta años, debe mirarse a Laín Entralgo como un caso especial. Su fecunda y docta pluma supera en mucho la capacidad del más prolífico de sus contemporáneos. Hace algún tiempo se le preguntó, a través de la Radio Nacional de España, cuál era su secreto para poder acumular tantos y tan dis

  16. Symposium by NATO Defense Research Group Panel VIII on Computer-Based Instruction in Military Environments

    CERN Document Server

    Weddle, Peter

    1987-01-01

    This collection of papers is the result of a symposium sponsored by NATO's Defense Research Group Panel VIII in the Spring of 1985. The symposium came into being when it became obvious to the NATO countries that research, development and utilization of advanced technologies for training was the best means of increasing both training effectiveness and efficiency. This symposium was the second in a series of three devoted to training. The series was structured to cover all aspects of training. The first series addressed the value of training, the second one dealt with the application of training technologies and the third and last of the series focused on academic issues concerned with the effect of prior learning on subsequent learning. The fact that a major American publisher has determined that computer based instruction is the technology of greatest interest to the NATO community is not surprising. Advances in microprocessor technology have revolutionized both how and where we train. During this symposium t...

  17. PENERAPAN PENDEKATAN CINEMATHERAPY UNTUK MENINGKATKAN PERILAKU PROSOSIAL PADA SISWA KELAS VIII DI BOSOWA INTERNATIONAL SCHOOL MAKASSAR

    Directory of Open Access Journals (Sweden)

    Haeruddin Niva

    2016-06-01

    Full Text Available The objectives of the research are: (i to know the prosocial behavioral level of the students in Bosowa International School Makassar before and after giving cinematography approach, and (ii to know whether or not the approach is able to enhance the prosocial behavior of the students in Bosowa International School Makassar. The research is a quantitative research using experimental method. The research design used is quasi experimental design with non-equivalent control group design. The data collection technique applied is scale and FGD (Focus Group Discussion. The findings shows that (i the prosocial behavioral level of the students was low in pretest while after giving treatment there were significant increase to the prosocial behavior in the experimental group, and (ii the cinematography approach was able to increase the prosocial behavior of the Grade VIII students in Bosowa Internatinal School Makassar. 

  18. Naked DNA transfer of Factor VIII induced transgene-specific, species-independent immune response in hemophilia A mice.

    Science.gov (United States)

    Ye, Peiqing; Thompson, Arthur R; Sarkar, Rita; Shen, Zhenping; Lillicrap, David P; Kaufman, Randal J; Ochs, Hans D; Rawlings, David J; Miao, Carol H

    2004-07-01

    The development of antibodies to a previously unexpressed protein product may limit the success of human gene therapy approaches. We inserted B-domain-deleted factor VIII (FVIII) cDNA of human, canine, or murine origin into the multiple cloning site of a liver-specific vector, pBS-HCRHPI-A, to yield plasmids pBS-HCRHPI-FVIIIA, pBS-HCRHPI-cFVIIIA, and pBS-HCRHPI-mFVIIIA, respectively. Fifty micrograms of each plasmid in 2 ml of solution was rapidly injected into the tail vein of three groups of hemophilia A mice. Factor VIII levels ranging from 3 to 12 IU/ml were obtained from all three groups (normal is 1 IU/ml in human plasma) 3 days after treatment. These initial very high levels of functional human, canine, or murine factor VIII, however, fell gradually to undetectable levels within 2-3 weeks, and their disappearance correlated with the generation of high-titer, inhibitory anti-FVIII antibodies. Notably, this immune response occurred independent of the species of origin of the exogenous factor VIII. Antibody titers to factor VIII were detected beginning at 2 weeks, reached a plateau and remained at high levels for over 6 months. The majority of anti-hFVIII IgG was IgG1 isotype specific, suggesting a humoral response mediated by Th2-induced signals. Consistent with this idea, in a separate group of mice treated with pBS-HCRHPI-FVIIIA, transient immunosuppression by cyclophosphamide significantly delayed (5/6) or abolished (1/6) inhibitory antibody formation against the transgene.

  19. Molecular Analysis of Factor VIII and Factor IX Genes in Hemophilia Patients: Identification of Novel Mutations and Molecular Dynamics Studies

    Science.gov (United States)

    Al-Allaf, Faisal A.; Taher, Mohiuddin M.; Abduljaleel, Zainularifeen; Bouazzaoui, Abdellatif; Athar, Mohammed; Bogari, Neda M.; Abalkhail, Halah A.; Owaidah, Tarek MA.

    2017-01-01

    Background Hemophilias A and B are X-linked bleeding disorders caused by mutations in the factor VIII and factor IX genes, respectively. Our objective was to identify the spectrum of mutations of the factor VIII and factor IX genes in Saudi Arabian population and determine the genotype and phenotype correlations by molecular dynamics (MD) simulation. Methods For genotyping, blood samples from Saudi Arabian patients were collected, and the genomic DNA was amplified, and then sequenced by Sanger method. For molecular simulations, we have used softwares such as CHARMM (Chemistry at Harvard Macromolecular Mechanics; http://www.charmm-gui.org) and GROMACS. In addition, the secondary structure was determined based on the solvent accessibility for the confirmation of the protein stability at the site of mutation. Results Six mutations (three novel and three known) were identified in factor VIII gene, and six mutations (one novel and five known) were identified in factor IX gene. The factor VIII novel mutations identified were c.99G>T, p. (W33C) in exon 1, c.2138 DelA, p. (N713Tfs*9) in eon14, also a novel mutation at splicing acceptor site of exon 23 c.6430 - 1G>A. In factor IX, we found a novel mutation c.855G>C, p. (E285D) in exon 8. These novel mutations were not reported in any factor VIII or factor IX databases previously. The deleterious effects of these novel mutations were confirmed by PolyPhen2 and SIFT programs. Conclusion The protein functional and structural studies and the models built in this work would be appropriate for predicting the effects of deleterious amino acid substitutions causing these genetic disorders. These findings are useful for genetic counseling in the case of consanguineous marriages which is more common in the Saudi Arabia. PMID:28270892

  20. Molecular Analysis of Factor VIII and Factor IX Genes in Hemophilia Patients: Identification of Novel Mutations and Molecular Dynamics Studies.

    Science.gov (United States)

    Al-Allaf, Faisal A; Taher, Mohiuddin M; Abduljaleel, Zainularifeen; Bouazzaoui, Abdellatif; Athar, Mohammed; Bogari, Neda M; Abalkhail, Halah A; Owaidah, Tarek Ma

    2017-04-01

    Hemophilias A and B are X-linked bleeding disorders caused by mutations in the factor VIII and factor IX genes, respectively. Our objective was to identify the spectrum of mutations of the factor VIII and factor IX genes in Saudi Arabian population and determine the genotype and phenotype correlations by molecular dynamics (MD) simulation. For genotyping, blood samples from Saudi Arabian patients were collected, and the genomic DNA was amplified, and then sequenced by Sanger method. For molecular simulations, we have used softwares such as CHARMM (Chemistry at Harvard Macromolecular Mechanics; http://www.charmm-gui.org) and GROMACS. In addition, the secondary structure was determined based on the solvent accessibility for the confirmation of the protein stability at the site of mutation. Six mutations (three novel and three known) were identified in factor VIII gene, and six mutations (one novel and five known) were identified in factor IX gene. The factor VIII novel mutations identified were c.99G>T, p. (W33C) in exon 1, c.2138 DelA, p. (N713Tfs*9) in eon14, also a novel mutation at splicing acceptor site of exon 23 c.6430 - 1G>A. In factor IX, we found a novel mutation c.855G>C, p. (E285D) in exon 8. These novel mutations were not reported in any factor VIII or factor IX databases previously. The deleterious effects of these novel mutations were confirmed by PolyPhen2 and SIFT programs. The protein functional and structural studies and the models built in this work would be appropriate for predicting the effects of deleterious amino acid substitutions causing these genetic disorders. These findings are useful for genetic counseling in the case of consanguineous marriages which is more common in the Saudi Arabia.