Influences on the American Geographer Samuel Griswold Goodrich.

Science.gov (United States)

Smith, Ben A.; Vining, James W.

1989-01-01

Describes the influences of religion, upbringing, and other scholars on Samuel Griswold Goodrich, an early nineteenth-century U.S. geographer. Discusses Goodrich's contribution to improving early geography textbooks and his pioneering role in book publishing. Notes Goodrich's realism and moral undertones in geography books for children, written…

Soul / Randy Becker, Bill Evans, Evelin Samuel ; interv. Sven Sapelson

Index Scriptorium Estoniae

Becker, Randy

2007-01-01

The Soulbop Bandi rajajad Randy Becker ja Bill Evans ning meie Evelin Samuel gospeli ja rhytmblues'i juurtega soulist. Lk. 72-73 Inessa Josingu ja Ande Kaalepi souliteemaline fotolavastusega ruumikujundus

O humano desumanizado num mundo sem sentido: Samuel Beckett e o herói absurdo = The dehumanized human being in a nonsense world: Samuel Beckett and the absurd hero

OpenAIRE

Maristela Kirst de Lima Girola

2011-01-01

Este ensaio tem como objetivo discutir a construção das personagens emEsperando Godot, de Samuel Beckett, apoiando-se nos estudos de Martin Esslin sobre o Teatro do Absurdo, uma forma de drama que enfatiza o absurdo da existência humana, empregando fragmentação, repetição e ininteligibilidade, como reação artística à Segunda Guerra Mundial.This essay discusses the construction of the characters in Waiting for Godot by Samuel Beckett, based on Martin Esslin’s studies on the Theatre of the Absu...

As Placas de Petri de Samuel

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Araújo, Maria Valéria Pereira de

2014-12-01

Full Text Available The case teaching "The Petri dishes of Samuel" mentions a real situation occurred in a small business Medical Laboratory located in the city of Natal-RN. The dilemma of the case comes to a decision-making situation involving João, Director of the Laboratory Tércio Rosado and responsible for the human resources sector of the organization. The case is narrated from his point of view which faces a situation where one employee who works at the company for 25 years can not get adapted to the new technologies of the Medical Laboratory area, although the employee possesses behavioral and attitudinal competences which sets it apart from other professionals. After several attempts of training processes, trying to make Samuel adapt his behavior to the new technological requirements of the position, none of them were successful. Facing the situation the Director had a dilemma to solve: keep him in the company or not? If the company remains the employee, it might discourage the learning development of the other ones? On the other hand, the company would have other alternatives of training him in order to develop the required skills? What could be done? The case was constructed from observational data and informal conversations with employees and with the former owners of the company. Fictitious names were used to preserve the identity of the involved.

A Dual Coding Theoretical Model of Decoding in Reading: Subsuming the LaBerge and Samuels Model

Science.gov (United States)

Sadoski, Mark; McTigue, Erin M.; Paivio, Allan

2012-01-01

In this article we present a detailed Dual Coding Theory (DCT) model of decoding. The DCT model reinterprets and subsumes The LaBerge and Samuels (1974) model of the reading process which has served well to account for decoding behaviors and the processes that underlie them. However, the LaBerge and Samuels model has had little to say about…

Una carta de pésame en arameo de Samuel ha-Naguid

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Alba Cecilia, Amparo

2007-12-01

Full Text Available In this article we offer a Spanish translation with a commentary of an Aramaic letter of consolation written by Samuel ha-Naguid and sent to R. Ḥananel b. Ḥušiel, lamenting the death of R. Ḥušiel b. Elḥanán, his father.

En el presente artículo ofrecemos la traducción y el estudio de la carta de pésame enviada por Samuel ha-Naguid a R. Ḥananel b. Ḥušiel por la muerte de R. Ḥušiel b. Elḥanán, su padre.

Strategic Entrepreneurship Version 2: A Reconceptualisation and Extension of Ireland, Hitt and Sirmon's Model for Growth and Wealth Creation in Firms

OpenAIRE

Soh, Hian Quan

2006-01-01

The main objectives of firms regardless of size are wealth creation and growth. One promising avenue for firms to stimulate further growth and create additional wealth is through entrepreneurial opportunities. However, there is the danger that opportunity-seeking behaviour can become reckless, draining resources and damaging the competitive base of the firm. It is on this basis that Ireland, Hitt and Sirmon (2003) proposed Strategic Entrepreneurship: the combination of opportunity-seeking a...

Ühe suve akvarellid / Evelin Samuel ja Liina Hergauk

Index Scriptorium Estoniae

Samuel, Evelin, 1975-

2015-01-01

Roosanupuline kampsun, idee ja teostus Evelin Samuel. Vanaroosa pluus ja barett, idee ja teostus Ruta Tännav. Mohäärlõngast topp, idee ja teostus Anna Verschik. Linane topp, idee ja teostus Liina Hergauk. Pitsmustritega mohäärkleit, idee ja teostus Ruta Tännav. Puuvillane topp, idee ja teostus Anna Verschik

75 FR 27286 - McKelvie Geographic Area Range Allotment Management Planning on the Samuel R. McKelvie National...

Science.gov (United States)

2010-05-14

... range allotment management planning on the McKelvie Geographic Area, Samuel R. McKelvie National Forest... DEPARTMENT OF AGRICULTURE Forest Service McKelvie Geographic Area Range Allotment Management Planning on the Samuel R. McKelvie National Forest, Bessey Ranger District in Nebraska AGENCY: Forest...

New documents on Samuel Usque, the author of the Consolaçam as tribulaçoens de Israel

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Guerrini, Maria Teresa

2001-06-01

Full Text Available Samuel Usque was a sixteenth-century Ferrara merchant and man of letters. Usque and Beatriz de Luna [Gracia Nasi] collaborated in the well-known task of reeducating Marranos in the precepts of normative Judaism. In addition, he represented Brianda Mendes in business trading in Antwerp, Ferrara, Venice and Ancona.Samuel Usque, literato y mercader en Ferrara en el siglo XVI, compartió con Beatriz de Luna [Gracia Nasi] el ya bien conocido proyecto cultural de la reeducación de los marranos en el judaismo. Además, Samuel Usque estuvo también al servicio de Brianda Méndez como mercader en Amberes, Ferrara, Venezia y Ancona.

O humano desumanizado num mundo sem sentido: Samuel Beckett e o herói absurdo = The dehumanized human being in a nonsense world: Samuel Beckett and the absurd hero

Directory of Open Access Journals (Sweden)

Maristela Kirst de Lima Girola

2011-01-01

Full Text Available Este ensaio tem como objetivo discutir a construção das personagens emEsperando Godot, de Samuel Beckett, apoiando-se nos estudos de Martin Esslin sobre o Teatro do Absurdo, uma forma de drama que enfatiza o absurdo da existência humana, empregando fragmentação, repetição e ininteligibilidade, como reação artística à Segunda Guerra Mundial.This essay discusses the construction of the characters in Waiting for Godot by Samuel Beckett, based on Martin Esslin’s studies on the Theatre of the Absurd, a form of drama that emphasizes the absurdity of human existence by employing split subjects, repetitions and meaninglessness as artistic reactions to World War II.

Williams syndrome

Science.gov (United States)

Williams-Beuren syndrome ... Williams syndrome is caused by not having a copy of several genes. It may be passed down in families. ... history of the condition. However, people with Williams syndrome have a 50% chance of passing the disorder ...

Mental Self-Exploration in Samuel Beckett's "Molloy": A Jungian Approach

Science.gov (United States)

Jamalinesari, Ali; Feilinezhad, Nabieh

2015-01-01

Samuel Beckett is categorized as an absurdist dramatist. Martin Esslin in his book "The Theatre of Absurd," states that absurdist writers dealt with the theme of man's sense of anguish and torture caused by living without any purpose. All characters of Beckett's dramas are deformed just like Molloy who deteriorates as the novel comes to…

The case of Samuel Golubchuk and the right to live.

Science.gov (United States)

Jotkowitz, Alan; Glick, Shimon; Zivotofsky, Ari Z

2010-03-01

Samuel Golubchuk was unwittingly at the center of a medical controversy with important ethical ramifications. Mr. Golubchuk, an 84-year-old patient whose precise neurological level of function was open to debate, was being artificially ventilated and fed by a gastrostomy tube prior to his death. According to all reports he was neither brain dead nor in a vegetative state. The physicians directly responsible for his care had requested that they be allowed to remove the patient from life support against the wishes of the patient's family. Concurrently the Manitoba College of Physicians and Surgeons released a statement which states that the final decision to withdraw life support lies with the physician. In our opinion the statement is ethically problematic for a number of reasons. 1. It is an affront to the guiding principles of Western medical ethics: patient autonomy and human freedom. 2. The position of Samuel Golubchuk's physicians and the new statement lack cultural sensitivity towards other traditions. 3. In modern society there exists an erosion of a basic attitude towards the value of life. 4. The ability of physicians to predict life expectancy in terminally ill patients has been shown repeatedly to be quite limited.

On the Samuel solution to the strong CP problem within QCD

International Nuclear Information System (INIS)

Dowrick, N.J.; McDougall, N.A.

1993-01-01

Samuel has recently proposed a mechanism whereby long-range interactions between topological charges may remove the potential for CP violation in QCD. In principle, these interactions could be attractive, repulsive, or a mixture of the two. We consider these possibilities and conclude that the mechanism is unlikely to be realized in any case. (orig.)

On the Samuel solution to the strong CP problem within QCD

Energy Technology Data Exchange (ETDEWEB)

Dowrick, N.J. (Department of Physics, Oxford (United Kingdom)); McDougall, N.A. (National Lab. for High Energy Physics (KEK), Tsukuba, Ibaraki (Japan))

1993-07-05

Samuel has recently proposed a mechanism whereby long-range interactions between topological charges may remove the potential for CP violation in QCD. In principle, these interactions could be attractive, repulsive, or a mixture of the two. We consider these possibilities and conclude that the mechanism is unlikely to be realized in any case. (orig.)

33 CFR 167.1702 - In Prince William Sound: Prince William Sound Traffic Separation Scheme.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: Prince William Sound Traffic Separation Scheme. 167.1702 Section 167.1702 Navigation and Navigable Waters COAST....1702 In Prince William Sound: Prince William Sound Traffic Separation Scheme. The Prince William Sound...

(Almost anonymous: collaborators of Samuel das Neves technical office in the early 1910s

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Ana Paula Nascimento

2018-04-01

Full Text Available The presence of collaborators in engineering and architecture offices is an insufficiently researched subject, most of which remain unknown even in specialized publications. This paper analyzes the participation of some professionals in Samuel das Neves Technical Office (Escritório Técnico Samuel das Neves during the first two decades of the 20th century, especially about works related to the State Penitentiary Competition (Concurso da Penitenciária do Estado and to São Paulo’s Master Plan (Plano Melhoramentos. Most of them were foreigners with extensive professional knowledge and who worked at the São Paulo headquarters of the company in its best known and commented period: Carlos Escobar, Giulio Micheli, Giuseppe Sacchetti, A. Maurice de Ladrière, José Talarico, and Giácomo Corberi.

Samuel Thomas Soemmerring (1755-1830): The Naming of Cranial Nerves.

Science.gov (United States)

Pearce, John M S

2017-01-01

Samuel Thomas Soemmerring was a Prussian polymathic doctor with remarkable achievements in anatomy, draftsmanship and inventions. His naming of 12 pairs of cranial nerves in his graduation thesis is of particular importance. He also gave original descriptions of the macula, sensory pathways and of the substantia nigra. His non-medical contributions were diverse and included criticism of the guillotine, invention of a telegraphic system, and discoveries in palaeontology. © 2017 S. Karger AG, Basel.

Alfred Russel Wallace’s record of his consignments to Samuel Stevens, 1854-1861

NARCIS (Netherlands)

Baker, D.B.

2001-01-01

An annotated facsimile of those pages of Alfred Russel Wallace’s notebook recording his consignments from the Malay Archipelago to his London agent, Samuel Stevens, is provided. Records of individual consignments are linked with the stages of Wallace’s and Charles Allen’s itineraries to which they

[Williams-Beuren syndrome (Williams syndrome). Case report].

Science.gov (United States)

Miklós, Györgyi; Fekete, György; Haltrich, Irén; Tóth, Miklós; Reismann, Péter

2017-11-01

Williams syndrome is a rare genetic disorder, that occurs equally in all ethnic groups and both sexes. The diagnosis might be missed during childhood in mild cases. However, establishing the diagnosis is important, not only to find the cause of intellectual disability but to look for cardiovascular, endocrine, psychiatry, urology and other conditions, which can occur at any age in the patients' lifetime. This case report presents the story of 47-year-old woman, who was admitted with haematemesis. During her stay on the ward, in the light of the distinctive facial features, mental retardation, and social behaviour patterns, the possibility of Williams syndrome emerged. Later, the diagnosis was confirmed by genetic analysis. This female is the oldest living patient with Williams syndrome in Hungary. Orv Hetil. 2017; 158(47): 1883-1888.

76 FR 70711 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2011-11-15

... L BEKKEDAHL, LARRY N BELL, MELODY C BIENIAWSKI, ANDREW J BIERBOWER, WILLIAM J BISHOP, CLARENCE T... BROWN, FRED L BROWN, STEPHANIE H BRUCE, SANDRA D BRYAN, PAUL F BRYAN, WILLIAM N BURROWS, CHARLES W BUTTRESS, LARRY D BUZZARD, CHRISTINE M CADIEUX, GENA E CALBOS, PHILIP T CALLAHAN, SAMUEL N CAMPAGNONE, MARI...

J.M.Coetzee: On the Samuel Beckett’s alley

Directory of Open Access Journals (Sweden)

Diego Sheinbaum

2015-02-01

Full Text Available The author shows the influence of Samuel Beckett’s work in the oeuvre of the South African writer. He analyzes the first two novels of J. M. Coetzee, Dusklands (1974 and In the Hearth of the Country (1977 in order to explain how their protagonists share the solipsism of Beckett’s characters; however, their fate changes under the logic of colonialism. From this zero degree of writing, the characters of the South African novelist begin a journey that, in philosophical terms, takes them from the Cartesian ego towards the horizon of Hegelian recognition.

78 FR 70027 - Senior Executive Service; Performance Review Board

Science.gov (United States)

2013-11-22

..., WILLIAM N. BURROWS, CHARLES W. BUTTRESS, LARRY D. CADIEUX, GENA E. CALBOS, PHILIP T. CALLAHAN, SAMUEL N..., LARRY N. BELL, MELODY C. BESTANI, ROBERT M. BIENIAWSKI, ANDREW J. BIERBOWER, WILLIAM J. BINKLEY, JOHN S..., STAN M. KEARNEY, JAMES H. KELLY, HENRY C. KELLY, JOHN E. KELLY, LARRY C. KENCHINGTON, HENRY S. KENDELL...

D r . C. J. G oslinga , De boeken Samuel opnieuw uit die grondtekst ...

African Journals Online (AJOL)

Test

nie tot 'n redelike vertaling kom nie as ons nie van die oorgelewerde. Hebreeuse teksvorm afwyk nie. Deur die vonds van stukke uit Samuel in een van die Dooie See grotte sal die tekskritiek van hierdie boek in die komende jare vermoedelik dikwels ter sprake kom; dit is wel duidelik dat die lesings van die Griekse vertaling ...

Samuel Beckett and music an absurd essay about the idea of musicality and musical form in Samuel Beckett’s short pieces - influences and possibilities

Directory of Open Access Journals (Sweden)

Mosusova Nadežda

2004-01-01

Full Text Available The premise of musicality of Beckett’s short dramas contains more questions than answers. Is the musicality of text present only in the work of Samuel Beckett? Do only the (musical stage remarks in Beckett’s dramas suggest the idea of musicality? Can the absurdity of his output be expressed with music and through music? Some short musical compositions, especially by Alexandre Scriabine, can be in some way compared with Beckett’s "dramaticules", but only in form not in the meaning and musical language. The question of hidden influences remains to be developed.

Striding Out in the Opposite Direction: The Journalism Career of George Samuel Schuyler, Iconoclast.

Science.gov (United States)

Fleener, Nickieann

Written in a biographical framework, an overview of George Samuel Schuyler's life and his career in journalism is presented in this paper. The preparation that Schuyler had for his career, the positions within journalism he held, and the major writing projects he undertook are discussed. The question of whether there is anything unique or…

Minimalist Theater and the Classroom: Some Experiments with Shakespeare and Beckett.

Science.gov (United States)

Homan, Sidney

1990-01-01

Argues in favor of using minimalist theater when teaching literature. Describes how minimalist theater was used to teach works by William Shakespeare and Samuel Beckett to undergraduate students. (PRA)

On authorship in Samuel Beckett’s prose

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Willian André

2014-06-01

Full Text Available This study aims at building a reflection on the notion of authorship in Samuel Beckett’s work, with a main focus on his short prose from the 60s and 70s. Thereunto, supported by the writings of Maurice Blanchot, S. E. Gontarski, João Adolfo Hansen and Hugh Kenner, we draw a route that starts with the Beckettian post-war trilogy, going through the subsequent productions that culminate in the short pieces outlined by the author after the publishing of How It Is (1961. As we take the path run by the Irish writer in his deal with failure (a path full of mud and light-grey-dark oscillations, we experience the rise of a paradoxical impression: the more severe are Beckett’s attacks against the shapes of the I, testifying the dilution of identity, more accurate become the shapes surrounding the idea of “author” that surmounts the whole of his literary project.

The four medical theses of Samuel Hahnemann (1755-1843).

Science.gov (United States)

Lang, Christoph Jg

2016-05-01

Samuel Hahnemann, the founder of homoeopathy, over a period of 33 years wrote four medical theses at three different universities. The first, in 1779 at the University of Erlangen, Franconia, dealt with agents that allegedly induce spasms, granting him a MD degree. The second two theses in 1784 dealt with obstetrical matters and were imposed upon him by the University of Wittenberg, Saxony, for becoming a medical officer, a position he apparently aspired to mostly for financial reasons. The fourth thesis in 1812 at the University of Leipzig, Saxony, his most elaborate dissertation on a toxic plant, white hellebore, served as a habilitation, allowing him to hold university lectures in order to disseminate his new ideas. © The Author(s) 2014.

Raymond Williams and local cultures

OpenAIRE

B Longhurst

1991-01-01

In this paper it is maintained that Raymond Williams's writings on culture are of great importance to current developments in cultural geography. His work is periodised into three stages and its different subject matters identified. An interpretation of Williams's theory of culture is offered which places particular emphasis on his concepts of 'structure of feeling' and 'knowable community'. The creative tension between Williams's holistic treatment of culture and his stress on cultural strug...

Studies in Interior Design

Science.gov (United States)

Environ Planning Design, 1970

1970-01-01

Floor plans and photographs illustrate a description of the Samuel C. Williams Library at Stevens Institute of Technology, Hoboken, N.J. The unusual interior design allows students to take full advantage of the library's resources. (JW)

O humano desumanizado num mundo sem sentido: Samuel Beckett e o herói absurdo - doi: 10.4025/actascilangcult.v33i1.6485

OpenAIRE

Girola, Maristela Kirst de Lima; PUCRS

2011-01-01

Este ensaio tem como objetivo discutir a construção das personagens em Esperando Godot, de Samuel Beckett, apoiando-se nos estudos de Martin Esslin sobre o Teatro do Absurdo, uma forma de drama que enfatiza o absurdo da existência humana, empregando fragmentação, repetição e ininteligibilidade, como reação artística à Segunda Guerra Mundial. This essay discusses the construction of the characters in Waiting for Godot by Samuel Beckett, based on Martin Esslin’s studies on the Theatre of the...

Famous people with Tourette's syndrome: Dr. Samuel Johnson (yes) & Wolfgang Amadeus Mozart (may be): Victims of Tourette's syndrome?

Science.gov (United States)

Bhattacharyya, Kalyan B; Rai, Saurabh

2015-01-01

Tourette's syndrome is a clinical condition characterized by multiple motor tics and vocal tics which occurs in the age range 5-25 years and the intensity of the symptoms changes with time. It is felt that at least two remarkable personalities namely, Dr. Samuel Johnson from England, a man of letters and the compiler of the first ever English dictionary, and Wolfgang Amadeus Mozart from Austria, one of the greatest musical genius of all time, possibly suffered from this condition. Tourette's syndrome is often described as the classical borderzone between neurology and psychiatry and every neurologist wonders at the curious and fascinating clinical features of this condition. It seems that at least two remarkable personalities, Dr. Samuel Johnson, a man of letters and the first person to compile an English dictionary, and Wolfgang Amadeus Mozart, arguably the most creative musical composer of all time, were possibly afflicted with this condition.

An interview with Samuel Shem, author of 'The House of God'.

Science.gov (United States)

Brash, Claire

2017-07-01

Dr Stephen Bergman, Professor of medical humanities at New York University, writes under the name Samuel Shem. He is an acclaimed author of several novels, plays and textbooks, and his work has been translated into several languages -'The House of God' his first novel has sold over 3 million copies. His work exposes the potential moral challenges of the medical workplace and the connection between values, good relationships and healing. In 2015 he visited the UK for medical humanities academic tour which included keynote talks at the RCGP 2015 Annual Conference and at the Royal Society of Medicine. Claire Brash interviewed him at the Royal Society of Medicine.

The Connection of Samuel Chapman Armstrong as both Borrower and Architect of Education in Hawai'i

Science.gov (United States)

Beyer, C. Kalani

2007-01-01

Samuel Chapman Armstrong is well known for establishing Hampton Institute, the institution most involved with training black teachers in the South after the Civil War. It is less known that he was born in Hawai'i to the missionary couple Reverend Richard and Clarissa Chapman Armstrong. His parents were members of the Fifth Company of missionaries…

Genetics Home Reference: Williams syndrome

Science.gov (United States)

... do well on tasks that involve spoken language, music, and learning by repetition (rote memorization). Affected individuals ... Resources (5 links) Disease InfoSearch: Williams syndrome Genetic Science Learning Center, University of Utah MalaCards: williams-beuren ...

Samuel Naeranus (1582-1641) en Johannes Naeranus (1608-1679) : twee remonstrantse theologen op de bres voor godsdienstige verdraagzaamheid

NARCIS (Netherlands)

Visser, S.J.

2011-01-01

In deze intellectuele dubbel biografie van Samuel en Johannes Naeranus staat de strijd voor religieuze verdraagzaamheid centraal. Visser laat zien hoe vader en zoon, leden van een bekend zeventiende-eeuws remonstrants predikantenge¬slacht, handen en voeten gaven aan hun streven naar tole¬rantie,

William Butler Yeats’s ‘The Symbolic System’ of William Blake

Directory of Open Access Journals (Sweden)

Arianna Antonielli

2008-03-01

Full Text Available The theosophical systems formulated by great poets, such as William Blake and William Butler Yeats, represent a personal idiosyncratic actualization of an ancient repertoire of magical symbols and occult visions. This study wants to focus the attention on the philosophical, mythical, and esoteric syncretism that W. B. Yeats drew from William Blake’s symbolical system. A fundamental step of Yeats’s deep investigation into the Blakean ‘vision’ was given by his monumental work, written together with Edwin John Ellis, on Blake’s poetic and pictorial production, completed in 1893 with a three-volume edition entitled The Works of William Blake, Poetic, Symbolic, and Critical. This work, published in London by Bernard Quaritch, deeply influenced Yeats’s symbolical and imaginary system, determining its subsequent development up to its codification in the volume of A Vision. With WWB, Yeats was able to systematize for the first time his own thought, giving unity to his Weltanschauung and his poetry. Following this hypothesis, I concentrated on Yeats’s and Ellis’s numerous analyses dedicated to Blake’s mythological and symbolical corpus and, in particular, I examined the last chapter of the first volume of the Quaritch edition. This chapter, entitled “The Symbolic System”, constitutes an unquestionable link between Yeats the reader and scholar of Blake, and Yeats the poet and follower of Blake.

South African Journal of Clinical Nutrition - Vol 31, No 1 (2018)

African Journals Online (AJOL)

Hospital-acquired malnutrition in children at a tertiary care hospital · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Del-Rossi Sean Quadros, Rose Kamenwa, Samuel Akech, William M. Macharia, 8-13 ...

A human neurodevelopmental model for Williams syndrome.

Science.gov (United States)

Chailangkarn, Thanathom; Trujillo, Cleber A; Freitas, Beatriz C; Hrvoj-Mihic, Branka; Herai, Roberto H; Yu, Diana X; Brown, Timothy T; Marchetto, Maria C; Bardy, Cedric; McHenry, Lauren; Stefanacci, Lisa; Järvinen, Anna; Searcy, Yvonne M; DeWitt, Michelle; Wong, Wenny; Lai, Philip; Ard, M Colin; Hanson, Kari L; Romero, Sarah; Jacobs, Bob; Dale, Anders M; Dai, Li; Korenberg, Julie R; Gage, Fred H; Bellugi, Ursula; Halgren, Eric; Semendeferi, Katerina; Muotri, Alysson R

2016-08-18

Williams syndrome is a genetic neurodevelopmental disorder characterized by an uncommon hypersociability and a mosaic of retained and compromised linguistic and cognitive abilities. Nearly all clinically diagnosed individuals with Williams syndrome lack precisely the same set of genes, with breakpoints in chromosome band 7q11.23 (refs 1-5). The contribution of specific genes to the neuroanatomical and functional alterations, leading to behavioural pathologies in humans, remains largely unexplored. Here we investigate neural progenitor cells and cortical neurons derived from Williams syndrome and typically developing induced pluripotent stem cells. Neural progenitor cells in Williams syndrome have an increased doubling time and apoptosis compared with typically developing neural progenitor cells. Using an individual with atypical Williams syndrome, we narrowed this cellular phenotype to a single gene candidate, frizzled 9 (FZD9). At the neuronal stage, layer V/VI cortical neurons derived from Williams syndrome were characterized by longer total dendrites, increased numbers of spines and synapses, aberrant calcium oscillation and altered network connectivity. Morphometric alterations observed in neurons from Williams syndrome were validated after Golgi staining of post-mortem layer V/VI cortical neurons. This model of human induced pluripotent stem cells fills the current knowledge gap in the cellular biology of Williams syndrome and could lead to further insights into the molecular mechanism underlying the disorder and the human social brain.

Rising intracellular zinc by membrane depolarization and glucose in insulin-secreting clonal HIT-T15 beta cells.

Science.gov (United States)

Slepchenko, Kira G; Li, Yang V

2012-01-01

Zinc (Zn(2+)) appears to be intimately involved in insulin metabolism since insulin secretion is correlated with zinc secretion in response to glucose stimulation, but little is known about the regulation of zinc homeostasis in pancreatic beta-cells. This study set out to identify the intracellular zinc transient by imaging free cytosolic zinc in HIT-T15 beta-cells with fluorescent zinc indicators. We observed that membrane depolarization by KCl (30-60 mM) was able to induce a rapid increase in cytosolic concentration of zinc. Multiple zinc transients of similar magnitude were elicited during repeated stimulations. The amplitude of zinc responses was not affected by the removal of extracellular calcium or zinc. However, the half-time of the rising slope was significantly slower after removing extracellular zinc with zinc chelator CaEDTA, suggesting that extracellular zinc affect the initial rising phase of zinc response. Glucose (10 mM) induced substantial and progressive increases in intracellular zinc concentration in a similar way as KCl, with variation in the onset and the duration of zinc mobilization. It is known that the depolarization of beta-cell membrane is coupled with the secretion of insulin. Rising intracellular zinc concentration may act as a critical signaling factor in insulin metabolism of pancreatic beta-cells.

The Invention of the Wireless Communication Engine

NARCIS (Netherlands)

van der Kooij, B.J.G.

2017-01-01

Wireless technology, taken for granted today, was once an innovative wonder that would forever change how the world communicates. Developed by Guglielmo Marconi in the latter half of the nineteenth century, wireless telegraphy combined advancements made by Samuel Morse, William Cooke, Charles

Samuel Wilks (1824-1911): neurologist and generalist of the Mid-Victorian Era.

Science.gov (United States)

Eadie, Mervyn J

2008-11-01

Sir Samuel Wilks, sometime Physician to Guy's Hospital and President of the Royal College of Physicians (1896-99), was regarded as the leading British scientific physician of his day. His contributions to gastroenterology, cardiology and clinical science in general have been emphasized in recent times. He also recognized that syphilis affected the internal organs as well as the skin. In 1866 he realised that epileptogenesis occurred in the cerebral cortex: independently of Sir Charles Locock (1799-1875), he discovered the antiepileptic properties of potassium bromide. He provided possibly the first account of alcoholic peripheral neuritis and published an early account of probable myasthenia gravis.

Handedness and corpus callosal morphology in Williams syndrome.

Science.gov (United States)

Martens, Marilee A; Wilson, Sarah J; Chen, Jian; Wood, Amanda G; Reutens, David C

2013-02-01

Williams syndrome is a neurodevelopmental genetic disorder caused by a hemizygous deletion on chromosome 7q11.23, resulting in atypical brain structure and function, including abnormal morphology of the corpus callosum. An influence of handedness on the size of the corpus callosum has been observed in studies of typical individuals, but handedness has not been taken into account in studies of callosal morphology in Williams syndrome. We hypothesized that callosal area is smaller and the size of the splenium and isthmus is reduced in individuals with Williams syndrome compared to healthy controls, and examined age, sex, and handedness effects on corpus callosal area. Structural magnetic resonance imaging scans were obtained on 25 individuals with Williams syndrome (18 right-handed, 7 left-handed) and 25 matched controls. We found that callosal thickness was significantly reduced in the splenium of Williams syndrome individuals compared to controls. We also found novel evidence that the callosal area was smaller in left-handed participants with Williams syndrome than their right-handed counterparts, with opposite findings observed in the control group. This novel finding may be associated with LIM-kinase hemizygosity, a characteristic of Williams syndrome. The findings may have significant clinical implications in future explorations of the Williams syndrome cognitive phenotype.

33 CFR 167.1700 - In Prince William Sound: General.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: General... Schemes and Precautionary Areas Pacific West Coast § 167.1700 In Prince William Sound: General. The Prince William Sound Traffic Separation Scheme consists of four parts: Prince William Sound Traffic Separation...

An Astrological Diary of the Seventeenth Century - Samuel Jeake of Rye 1652-1699

Science.gov (United States)

Hunter, Michael; Gregory, Annabel

1988-04-01

A seventeenth-century merchant and nonconformist from Rye in Sussex, Samuel Jeake had a passionate interest in astrology. In his diary--recently recovered in Los Angeles and published here for the first time--Jeake not only recorded the events of his life; he subjected them to astrological scrutiny, interspersing his text with horoscopes. The result is one of the most interesting 17th-century diaries to be published in many years, throwing important light on the history of astrology, commerce, medicine, and religion. An illuminating introduction by the editors places the diary in the context of the preoccupations and priorities of Jeake's age.

Resonance Ops: How Developing Social Movements Can Operationalize Ideologies

Science.gov (United States)

2016-12-01

Mobilization: An International Journal 1, no. 1 (September 1996): 1–15. Tzu , Sun . The Art of War. Translated by Samuel B. Griffith. New York: Oxford...PROFILE ....................................................................111  BIBLIOGRAPHY ...113 BIBLIOGRAPHY Andrews, William R. The Village War: Vietnamese Communist Revolutionary Activities in Dinh Tuong

Famous people with Tourette′s syndrome: Dr. Samuel Johnson (yes & Wolfgang Amadeus Mozart (may be: Victims of Tourette′s syndrome?

Directory of Open Access Journals (Sweden)

Kalyan B Bhattacharyya

2015-01-01

Full Text Available Tourette′s syndrome is a clinical condition characterized by multiple motor tics and vocal tics which occurs in the age range 5-25 years and the intensity of the symptoms changes with time. It is felt that at least two remarkable personalities namely, Dr. Samuel Johnson from England, a man of letters and the compiler of the first ever English dictionary, and Wolfgang Amadeus Mozart from Austria, one of the greatest musical genius of all time, possibly suffered from this condition. Tourette′s syndrome is often described as the classical borderzone between neurology and psychiatry and every neurologist wonders at the curious and fascinating clinical features of this condition. It seems that at least two remarkable personalities, Dr. Samuel Johnson, a man of letters and the first person to compile an English dictionary, and Wolfgang Amadeus Mozart, arguably the most creative musical composer of all time, were possibly afflicted with this condition.

Ostrich: Journal of African Ornithology - Vol 86, No 1-2 (2015)

African Journals Online (AJOL)

Movement ecology of five Afrotropical waterfowl species from Malawi, Mali and Nigeria § · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. John Y Takekawa, Shane R Heath, Samuel A Iverson, Nicolas Gaidet, Julien Cappelle, Tim Dodman, Ward Hagemeijer, William D Eldridge, ...

William Rowan Hamilton: Mathematical genius

International Nuclear Information System (INIS)

Wilkins, D.R.

2006-01-01

This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for quaternions and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as Hamiltonian and Hamiltonian system have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

Mental Self-Exploration in Samuel Beckett’s Molloy: A Jungian Approach

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Ali Jamalinesari

2015-02-01

Full Text Available Samuel Beckett is categorized as an absurdist dramatist. Martin Esslin in his book The Theatre of Absurd, states that absurdist writers dealt with the theme of man’s sense of anguish and torture caused by living without any purpose. All characters of Beckett’s dramas are deformed just like Molloy who deteriorates as the novel comes to an end. Actually, Beckett’s characters are wanderers who try to establish a sense of meaning for their existence; they are in search of self. As his works represent, Beckett uses Jungian archetypes in order to show the aspect of self. This article tries to demonstrate the lack of identity in Molloy’s Characters in the light of Jungian archetypes throughout the story. Keywords: Molloy, Identity, Archetype, Jung, Self, Deterioration

Rising Intracellular Zinc by Membrane Depolarization and Glucose in Insulin-Secreting Clonal HIT-T15 Beta Cells

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Kira G. Slepchenko

2012-01-01

Full Text Available Zinc (Zn2+ appears to be intimately involved in insulin metabolism since insulin secretion is correlated with zinc secretion in response to glucose stimulation, but little is known about the regulation of zinc homeostasis in pancreatic beta-cells. This study set out to identify the intracellular zinc transient by imaging free cytosolic zinc in HIT-T15 beta-cells with fluorescent zinc indicators. We observed that membrane depolarization by KCl (30–60 mM was able to induce a rapid increase in cytosolic concentration of zinc. Multiple zinc transients of similar magnitude were elicited during repeated stimulations. The amplitude of zinc responses was not affected by the removal of extracellular calcium or zinc. However, the half-time of the rising slope was significantly slower after removing extracellular zinc with zinc chelator CaEDTA, suggesting that extracellular zinc affect the initial rising phase of zinc response. Glucose (10 mM induced substantial and progressive increases in intracellular zinc concentration in a similar way as KCl, with variation in the onset and the duration of zinc mobilization. It is known that the depolarization of beta-cell membrane is coupled with the secretion of insulin. Rising intracellular zinc concentration may act as a critical signaling factor in insulin metabolism of pancreatic beta-cells.

William Rowan Hamilton: Mathematical genius

Energy Technology Data Exchange (ETDEWEB)

Wilkins, D.R. [School of Mathematics, Trinity College, Dublin (Ireland)]. E-mail: dwilkins@maths.tcd.ie

2005-08-01

This year Ireland celebrates the bicentenary of the mathematician William Rowan Hamilton, best remembered for 'quaternions' and for his pioneering work on optics and dynamics. Two centuries after his birth, the extent to which terms such as 'Hamiltonian' and 'Hamiltonian system' have entered the everyday language of mathematicians and physicists testifies to the continuing impact of the scientific work of William Rowan Hamilton. (U.K.)

33 CFR 110.233 - Prince William Sound, Alaska.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Prince William Sound, Alaska. 110... ANCHORAGES ANCHORAGE REGULATIONS Anchorage Grounds § 110.233 Prince William Sound, Alaska. (a) The anchorage grounds. In Prince William Sound, Alaska, beginning at a point at latitude 60°40′00″ N., longitude 146°40...

Cervical cancer in the work of the unconventional Samuel Pozzi (1846-1918), pioneer of modern gynaecology.

Science.gov (United States)

Karamanou, Marianna; Drogosis, Achilleas; Salakos, Nikolaos; Markatos, Kostas; Deligeoroglou, Efthimios; Androutsos, George

2018-01-01

Advocate of Lister's antiseptic techniques, promoter of anesthesia, professor of the first chair of gynaecology in Medical School of Paris, academician, successful politician, art collector, friend and lover of the famous, Samuel Pozzi lived a fascinating life. His book "Treatise of clinical and surgical gynaecology" published in 1890 became the gold standard in medical practice while his approach in the treatment of cervical cancer, including cases of pregnant women, remained in vogue for almost fifty years.

Williams Syndrome with a “Twist”

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Despoina Maritsi

2010-01-01

Full Text Available Williams syndrome is a rare genetic condition with multisystemic involvement, caused by a microscopic deletion in the chromosome band 7q11.23. We describe the first case of a toddler with Williams syndrome who developed Benign Paroxysmal Torticollis (BPT, a benign dystonic disorder of unknown aetiology.

Met fictieve peers op zoek naar de waarheid : Fictie als didactisch instrument in Verlicht-religieuze catechismussen van Samuel van Emdre (1781-1798)

NARCIS (Netherlands)

Dietz, F.M.

2016-01-01

Following the recent trend in scholarship that considers the Enlightenment as a dynamicprocess of Christian civilisation rather than secularisation, this article analyses how the Reformed minister Samuel van Emdre used catechisms to create an Enlightened religion. As a late eighteenth century

76 FR 1130 - Prince William Sound Resource Advisory Committee

Science.gov (United States)

2011-01-07

... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... conducted: The Prince William Sound Resource Advisory Committee (RAC) will be discussing and voting on...

77 FR 45331 - Prince William Sound Resource Advisory Committee

Science.gov (United States)

2012-07-31

... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... Prince William Sound Resource Advisory Committee (RAC) will be discussing and voting on proposals that...

Ending Caleb Williams: on storytelling influencing William Godwin’s politics

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Peterson Roberto da Silva

2017-12-01

Full Text Available William Godwin escreveu o romance gótico Things as They Are; or, the Adventures of Caleb Williams (“As Coisas como Elas São; ou, as Aventuras de Caleb Williams”, em tradução livre em 1794 para disseminar suas ideias filosóficas e políticas. Inicio o artigo revisando a literatura para demonstrar como sua teoria influenciou tanto sua decisão de escrever ficções quanto o tipo de ficção que ele escreveu, mostrando como o autor usou e inovou convenções do gênero gótico para transmitir suas ideias para um público mais amplo. Então comparo duas perspectivas divergentes na literatura quanto à maneira como suas narrativas influenciaram suas ideias políticas e filosóficas, em particular a partir de comentários acerca do significado e do impacto de mudanças de última hora ao desfecho de Caleb Williams. Argumento que essa relação ambígua entre narrativa e política na obra de Godwin é relevante para reflexões políticas contemporâneas sobre a relação entre representação e ação política, ou como narrativas sobre a condição humana e realidades políticas podem afetas as ideias, atitudes e relações sociais de seus narradores.

76 FR 18715 - Prince William Sound Resource Advisory Committee

Science.gov (United States)

2011-04-05

... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... meeting is open to the public. The following business will be conducted: The Prince William Sound Resource...

Williams propylene upgrading

Energy Technology Data Exchange (ETDEWEB)

Chappell, D. [Williams Energy Canada Inc., Edmonton, AB (Canada)

2004-07-01

Edmonton-based Williams Energy Canada Inc. extracts petrochemicals from oil sands and operates a straddle plant business and an olefins business. This presentation provided an update of both businesses and reviewed the advantage of polypropylene production in Alberta, with reference to premium markets and to comparative rail costs to Chicago via Texas, and rail costs to Chicago from Alberta. Williams' straddle plant business includes the Cochrane Straddle Plant, the Empress 2 Straddle Plant, and the Empress 5 Straddle Plant. The Fort McMurray Extraction Plant was also described along with the Redwater Olefins Fractionator and its potential for salt cavern storage and distribution. It was noted that Alberta is well positioned for polypropylene production because it already has a secure supply and an excellent distribution network. tabs., figs.

Williams propylene upgrading

International Nuclear Information System (INIS)

Chappell, D.

2004-01-01

Edmonton-based Williams Energy Canada Inc. extracts petrochemicals from oil sands and operates a straddle plant business and an olefins business. This presentation provided an update of both businesses and reviewed the advantage of polypropylene production in Alberta, with reference to premium markets and to comparative rail costs to Chicago via Texas, and rail costs to Chicago from Alberta. Williams' straddle plant business includes the Cochrane Straddle Plant, the Empress 2 Straddle Plant, and the Empress 5 Straddle Plant. The Fort McMurray Extraction Plant was also described along with the Redwater Olefins Fractionator and its potential for salt cavern storage and distribution. It was noted that Alberta is well positioned for polypropylene production because it already has a secure supply and an excellent distribution network. tabs., figs

Williams-Beuren's Syndrome: A Case Report.

Science.gov (United States)

Zamani, Hassan; Babazadeh, Kazem; Fattahi, Saeid; Mokhtari-Esbuie, Farzad

2012-01-01

Williams-Beuren syndrome is a rare familial multisystem disorder occurring in 1 per 20,000 live births. It is characterized by congenital heart defects (CHD), skeletal and renal anomalies, cognitive disorder, social personality disorder and dysmorphic facies. We present a case of Williams syndrome that presented to us with heart murmur and cognitive problem. A 5-year-old girl referred to pediatric cardiologist because of heart murmurs. She had a systolic murmur (2-3/6) in right upper sternal border with radiation to right cervical region. She also had a bulge forehead. Angiography showed mild supra valvular aortic stenosis and mild multiple peripheral pulmonary stenosis. Fluorescent in situ hybridization (FISH) was performed and the result was: 46.XX, ish del (7q11.2) (ELN X1) (7q22 X2) ELN deletion compatible with Williams syndrome. Peripheral pulmonary artery stenosis is associated with Noonan syndrome, Alagille syndrome, Cutis laxa, Ehler-Danlos syndrome, and Silver-Russel syndrome. The patient had peripheral pulmonary artery stenosis, but no other signs of these syndromes were present, and also she had a supravalvular aortic stenosis which was not seen in other syndromes except Williams syndrome. Conclusion. According to primary symptoms, paraclinical and clinical finding such as dysmorphic facies, cognitive disorder and congenital heart defect, Williams syndrome was the first diagnosis. We suggest a more attention for evaluating heart murmur in childhood period, especially when the patient has abnormal facial features or mental problem.

Williams-Beuren's Syndrome: A Case Report

Directory of Open Access Journals (Sweden)

Hassan Zamani

2012-01-01

Full Text Available Williams-Beuren syndrome is a rare familial multisystem disorder occurring in 1 per 20,000 live births. It is characterized by congenital heart defects (CHD, skeletal and renal anomalies, cognitive disorder, social personality disorder and dysmorphic facies. We present a case of Williams syndrome that presented to us with heart murmur and cognitive problem. A 5-year-old girl referred to pediatric cardiologist because of heart murmurs. She had a systolic murmur (2-3/6 in right upper sternal border with radiation to right cervical region. She also had a bulge forehead. Angiography showed mild supra valvular aortic stenosis and mild multiple peripheral pulmonary stenosis. Fluorescent in situ hybridization (FISH was performed and the result was: 46.XX, ish del (7q11.2 (ELN X1 (7q22 X2 ELN deletion compatible with Williams syndrome. Peripheral pulmonary artery stenosis is associated with Noonan syndrome, Alagille syndrome, Cutis laxa, Ehler-Danlos syndrome, and Silver-Russel syndrome. The patient had peripheral pulmonary artery stenosis, but no other signs of these syndromes were present, and also she had a supravalvular aortic stenosis which was not seen in other syndromes except Williams syndrome. Conclusion. According to primary symptoms, paraclinical and clinical finding such as dysmorphic facies, cognitive disorder and congenital heart defect, Williams syndrome was the first diagnosis. We suggest a more attention for evaluating heart murmur in childhood period, especially when the patient has abnormal facial features or mental problem.

Pride and penitence in some Tudor histories of Thomas Wolsey

African Journals Online (AJOL)

2016-05-26

May 26, 2016 ... Limitations of space have made it necessary to exclude many texts, including the poems of John Skelton; Polydore Vergil's Anglica historia; polemics by Robert. Barnes, Simon Fish, and William Tyndale; Samuel Rowley's play When You See Me,. You Know Me; the collection of poems Mirror for Magistrates ...

La retórica bajo el barniz de la lógica : Samuel Ramos y su discurso sobre la inferioridad mexicana

NARCIS (Netherlands)

Houvenaghel, E.M.H.

2014-01-01

Samuel Ramos reflects on the essence of the Mexican people in the philosophical essay El perfil del hombre y la cultura en M´exico (1934). He emphasizes the sentiment of inferiority and the desire to hide this inferiority by camouflage strategies as a distinctive characteristic of the Mexican. This

Met fictieve peers op zoek naar de waarheid. Fictie als didactisch instrument in Verlicht-religieuze catechismussen van Samuel van Emdre

Directory of Open Access Journals (Sweden)

F. Dietz

2016-09-01

Full Text Available Searching for Truth with Fictional Peers: Fiction as a Didactic Instrument in the Enlightenment Religious Catechisms of Samuel van Emdre (1781-1798. Following the recent trend in scholarship that considers the Enlightenment as a dynamicprocess of Christian civilisation rather than secularisation, this article analyses how the Reformed minister Samuel van Emdre used catechisms to create an Enlightened religion. As a late eighteenth century catechist Van Emdre faced an intriguing didactic paradox: while the genre of the catechism served to teach religious knowledge unambiguously, new Enlightened ideals of learning emphasised the value of curiosity and an active, searching learning style. This article shows how he resolved this paradox by introducing fictional strategies: increasingly he used fictional peers, interactive dialogue techniques and stylistic diversity. By these means, Van Emdres’ catechisms invited youngsters to model themselves upon their young peers in the texts and to absorb religious knowledge acquired and investigated independently. Aanhakend bij de recente historiografische tendens om de Nederlandse Verlichting te zien als een dynamisch beschavingsproces in plaats van een seculariseringsbeweging, analyseer ik in dit artikel hoe de predikant Samuel van Emdre een Verlichte religie creëerden in catechismussen. Als laatachttiende-eeuwse catecheet werd Van Emdre geconfronteerd met een didactische paradox: aan de ene kant was het catechismusgenre erop gericht om onwankelbare religieuze kennis over te dragen, maar aan de andere kant werd – in lijn met nieuwe Verlichte pedagogische idealen – belang gehecht aan nieuwsgierigheid en onderzoekende leerstijlen. Dit artikel laat zien hoe Van Emdre die paradox oploste door fictionele strategieën in zijn catechismussen te introduceren: hij gebruikte steeds meer fictieve peers, interactieve dialoogtechnieken en genrecombinaties. Daarmee nodigde hij jongeren uit om zichzelf te spiegelen

Samuel Hartlib on the death of Descartes: a rediscovered letter to Henry More

Science.gov (United States)

Penman, Leigh T. I.

2015-01-01

This paper discloses the content of a previously overlooked epistle by the Anglo-Prussian intelligencer Samuel Hartlib to Henry More concerning the death of René Descartes. After a discussion situating the letter within the sequence of the More–Hartlib correspondence, an analysis of the rhetorical structure of the epistle is offered, followed by a brief assessment of Hartlib's attitude towards Descartes, and the identification of his source concerning the news of the philosopher's death. An account of the transmission of the letter via a nineteenth-century periodical is also provided. The text of Hartlib's letter and an overlooked passage of Hartlib's diary concerning Descartes's death, which draws on the content of the More letter, are presented as appendixes.

William Wilde: Historian.

Science.gov (United States)

Geary, L

2016-05-01

This essay attempts to assess William Wilde as a social historian. It examines some of his contributions to the discipline of history and looks particularly at 'The food of the Irish', which was published in the Dublin University Magazine in February 1854.

Samuel Patton Impey, M.D. (Aberdeen) (1856-1928). Cape Town's primordial leprologist, dermatologist, radiotherapist and rock-art enthusiast.

Science.gov (United States)

Findlay, G H

1987-03-21

Samuel Impey was a noteworthy medical pioneer of the Cape Colony. He was the author of what was probably the first medical textbook of note to be written in South Africa, a Handbook of Leprosy, published in London in 1896. He carried much of the frontier spirit into the medical life of the time, entering vigorously into controversy and fresh developments. As an amateur artist, he also put forward some individual views on rock paintings.

Language and Communicative Development in Williams Syndrome

Science.gov (United States)

Mervis, Carolyn B.; Becerra, Angela M.

2007-01-01

Williams syndrome, a genetic disorder caused by a microdeletion of approximately 25 genes on chromosome 7q11.23, is associated with mild to moderate intellectual disability or learning difficulties. Most individuals with Williams syndrome evidence a cognitive profile including relative strengths in verbal short-term memory and language, and…

75 FR 39910 - Prince William Sound Resource Advisory Committee; Meeting

Science.gov (United States)

2010-07-13

... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee; Meeting AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource..., Anchorage, Alaska 99503. Send written comments to Prince William Sound Resource Advisory Committee, c/o USDA...

Tempo e percezione in The Body Artist di Don DeLillo e Ghost Trio di Samuel Beckett

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Davide Barbuscia

2013-03-01

Full Text Available This essay provides a critical analysis of Don DeLillo’s novel The Body Artist and Samuel Beckett’s work for television Ghost Trio. In particular it analyses the representation of time and its perception in both these works, highlighting some shared aesthetic modalities such as their attempt to depict duration through a poetics of slow motion. The essay also foregrounds how both these works give narrative form to Merleau-Ponty’s understanding of ‘time as its perception’.

Social Cognition in Williams Syndrome: Face Tuning.

Science.gov (United States)

Pavlova, Marina A; Heiz, Julie; Sokolov, Alexander N; Barisnikov, Koviljka

2016-01-01

Many neurological, neurodevelopmental, neuropsychiatric, and psychosomatic disorders are characterized by impairments in visual social cognition, body language reading, and facial assessment of a social counterpart. Yet a wealth of research indicates that individuals with Williams syndrome exhibit remarkable concern for social stimuli and face fascination. Here individuals with Williams syndrome were presented with a set of Face-n-Food images composed of food ingredients and in different degree resembling a face (slightly bordering on the Giuseppe Arcimboldo style). The primary advantage of these images is that single components do not explicitly trigger face-specific processing, whereas in face images commonly used for investigating face perception (such as photographs or depictions), the mere occurrence of typical cues already implicates face presence. In a spontaneous recognition task, participants were shown a set of images in a predetermined order from the least to most resembling a face. Strikingly, individuals with Williams syndrome exhibited profound deficits in recognition of the Face-n-Food images as a face: they did not report seeing a face on the images, which typically developing controls effortlessly recognized as a face, and gave overall fewer face responses. This suggests atypical face tuning in Williams syndrome. The outcome is discussed in the light of a general pattern of social cognition in Williams syndrome and brain mechanisms underpinning face processing.

Professor Samuel David Gross (1805-1884) and His Innovations in Surgery and Medicine.

Science.gov (United States)

Laios, Konstantinos

2018-06-01

Professor Samuel David Gross (1805-1884) is considered as one of the founders of American surgery. He was a skillful surgeon who could excellently perform a lithotomy, an amputation, and a cataract surgery. He introduced many new surgical techniques and designed new surgical and medical instruments. He expertise was not limited to surgery alone; he also published studies concerning internal medicine, pathology, experimental physiology, and pharmacology. His most important treatise was his 2-volume work, A System of Surgery, Pathological, Diagnostic, Therapeutic and Operative (1861), which was a standard reference book in surgery in the United States during the second half of 19th century. Gross received many honors during his life. He was active in the operating room until his death.

A new case of keratoconus associated with Williams-Beuren syndrome.

Science.gov (United States)

Viana, Melissa Machado; Frasson, Maria; Leão, Letícia Lima; Stofanko, Martin; Gonçalves-Dornelas, Higgor; Cunha, Pricila da Silva; de Aguiar, Marcos José Burle

2013-09-01

Williams-Beuren syndrome is a multisystemic genetic disorder caused by a contiguous gene deletion at 7q11.23. Keratoconus is a complex disease and it is suspected to have a genetic origin, although the specific gene responsible for keratoconus has not been identified. Although there are several ocular features in Williams-Beuren syndrome, keratoconus is not regularly described as part of this syndrome. To report a new patient with keratoconus and Williams-Beuren syndrome. This is the third case of an association between Williams-Beuren syndrome and keratoconus. The authors believe that the Williams-Beuren syndrome chromosome region can be a possible target for further investigation as the genetic basis of keratoconus.

Epistemologia pragmatyczna Michaela Williamsa (PRAGMATIST EPISTEMOLOGY BY MICHAEL WILLIAMS

Directory of Open Access Journals (Sweden)

Renata Ziemińska

2007-06-01

Full Text Available The article presents three main elements of Williams' epistemology: the concept of knowledge, the problem of skepticism and the concept of truth. Williams takes knowledge not as pure descriptive but partly normative concept (to know is to be engaged and entitled. He rejects the demonstrative conception of knowledge (knowledge is infallible and prefers the fallibilist conception of knowledge (knowledge is uncertain and fallible. Williams is good at bringing skeptical presuppositions to light: the demonstrative conception of knowledge and the conception of justification with Prior Grounding Requirement, epistemological realism and priority for internal knowledge. He rightly observes that when we change that presuppositions (skeptic's context, knowledge does exist. However, Williams-fallibilist is close to a skeptic: they both agree that our beliefs are uncertain. The difference is only whether some of our beliefs deserve to be called knowledge. The most important worries concern Williams' concept of truth (deflationary pragmatism. According to Williams truth has no nature and it is not a goal of inquiry. However, if truth is not a goal, we can hardly understand the previous discussion with skepticism and the defense of rationality.

Rethinking English phyisco-theology: Samuel Parker's Tentamina de Deo (1665).

Science.gov (United States)

Levitin, Dmitri

2014-01-01

Recent historiography has claimed that a radically new, non-dogmatic physico-theology gained prominence with, and simultaneously promoted, the new science. This article challenges this view by focusing on an important physico-theological work by the young Oxford cleric Samuel Parker, published in 1665. It received a glowing review in the first volume of the Philosophical Transactions and gained its author election to the Royal Society, yet has been almost entirely ignored by modern scholars. Parker's work demonstrates both how easily the pious rhetoric of the naturalists could be incorporated into the traditional--largely humanist--knowledge gained by a typical M.A. student in mid-seventeenth-century England. Moreover, far from being non-dogmatic, Parker's physico-theology culminated in a remarkable deployment of the new philosophy (specifically Thomas Willis's neurology) to explain scriptural passages referring to God's passions. Parker believed himself not to be doing something radically new, but to be working in the traditions of scholastic theology. At the same time, his work was one of the most important conduits for the early English reception of both Descartes and Gassendi.

33 CFR 161.60 - Vessel Traffic Service Prince William Sound.

Science.gov (United States)

2010-07-01

... William Sound. 161.60 Section 161.60 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... Movement Reporting System Areas and Reporting Points § 161.60 Vessel Traffic Service Prince William Sound... Cape Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between...

Skin findings in Williams syndrome.

Science.gov (United States)

Kozel, Beth A; Bayliss, Susan J; Berk, David R; Waxler, Jessica L; Knutsen, Russell H; Danback, Joshua R; Pober, Barbara R

2014-09-01

Previous examination in a small number of individuals with Williams syndrome (also referred to as Williams-Beuren syndrome) has shown subtly softer skin and reduced deposition of elastin, an elastic matrix protein important in tissue recoil. No quantitative information about skin elasticity in individuals with Williams syndrome is available; nor has there been a complete report of dermatologic findings in this population. To fill this knowledge gap, 94 patients with Williams syndrome aged 7-50 years were recruited as part of the skin and vascular elasticity (WS-SAVE) study. They underwent either a clinical dermatologic assessment by trained dermatologists (2010 WSA family meeting) or measurement of biomechanical properties of the skin with the DermaLab™ suction cup (2012 WSA family meeting). Clinical assessment confirmed that soft skin is common in this population (83%), as is premature graying of the hair (80% of those 20 years or older), while wrinkles (92%), and abnormal scarring (33%) were detected in larger than expected proportions. Biomechanical studies detected statistically significant differences in dP (the pressure required to lift the skin), dT (the time required to raise the skin through a prescribed gradient), VE (viscoelasticity), and E (Young's modulus) relative to matched controls. The RT (retraction time) also trended longer but was not significant. The biomechanical differences noted in these patients did not correlate with the presence of vascular defects also attributable to elastin insufficiency (vascular stiffness, hypertension, and arterial stenosis) suggesting the presence of tissue specific modifiers that modulate the impact of elastin insufficiency in each tissue. © 2014 Wiley Periodicals, Inc.

Discoverers of the universe William and Caroline Herschel

CERN Document Server

Hoskin, Michael

2011-01-01

Discoverers of the Universe tells the gripping story of William Herschel, the brilliant, fiercely ambitious, emotionally complex musician and composer who became court astronomer to Britain's King George III, and of William's sister, Caroline, who assisted him in his observations of the night sky and became an accomplished astronomer in her own right. Together, they transformed our view of the universe from the unchanging, mechanical creation of Newton's clockmaker god to the ever-evolving, incredibly dynamic cosmos that it truly is. William was in his forties when his amateur observations usi

Sienten Phyllachora maydis Maubl. ja Monographella maydis Müller & Samuels aiheuttaman asfalttilaikkutaudin esiintyvyys maissilla (Zea mays L.) Nicaraguassa

OpenAIRE

Höckerstedt, Layla

2014-01-01

Maissi (Zea mays L.) on yksi maailman merkittävimmistä ravintokasveista. Nicaraguassa maissia tuottavat lähinnä pienviljelijät, joilla ei ole mahdollisuutta käyttää maatalouskemikaaleja tautien torjuntaan. Suurin osa maissille tauteja aiheuttavista patogeeneistä on sieniä, kuten myös mustalaikkua aiheuttava ehdoton loissieni Phyllachora maydis Maubl. Yhdessä endofyyttisen sienen Monographella maydis Müller & Samuels kanssa, nämä yksinään melko harmittomat sienet voivat aiheuttaa asfalttilaiku...

MINERAL WATERS ACROSS THE CHANNEL: MATTER THEORY AND NATURAL HISTORY FROM SAMUEL DUCLOS'S MINERALLOGENESIS TO MARTIN LISTER'S CHYMICAL MAGNETISM, CA. 1666-86.

Science.gov (United States)

Roos, Anna Marie; Boantza, Victor D

2015-12-20

Our essay analyses a little-known book, Observations sur les eaux minerales des plusieurs provinces de France (1675), which is a study of French mineral waters, commissioned by and conducted at the French Royal Academy of Science (est. 1666). Its author, Samuel Cottereau Duclos (1598-1685), was a senior founding figure of the Academy, its chief chymist and one of its most influential members. We examine Observations with a focus on the changing attitudes towards chymical knowledge and practice in the French Academy and the Royal Society of London in the period 1666-84. Chymistry was a fundamental analytical tool for seventeenth-century natural historians, and, as the work of Lawrence Principe and William Newman has shown, it is central to understanding the 'long' Scientific Revolution. Much study has also been done on the developing norms of openness in the dissemination and presentation of scientific, and particularly chymical knowledge in the late seventeenth century, norms that were at odds with traditions of secrecy among individual chymists. Between these two standards a tension arose, evidenced by early modern 'vociferous criticisms' of chymical obscurity, with different strategies developed by individual philosophers for negotiating the emergent boundaries between secrecy and openness. Less well studied, however, are the strategies by which not just individuals but also scientific institutions negotiated these boundaries, particularly in the formative years of their public and political reputation in the late seventeenth century. Michael Hunter's recent and welcome study of the 'decline of magic' at the Royal Society has to some extent remedied these omissions. Hunter argues that the Society--as a corporate body--disregarded and avoided studies of magical and alchemical subjects in the late seventeenth century. Our examination problematizes these distinctions and presents a more complex picture.

Investigating the ''social brain'' through Williams syndrome

International Nuclear Information System (INIS)

Nagamine, Masanori; Mimura, Masaru; Reiss, A.L.; Hoeft, F.

2010-01-01

Recent advances in social cognitive neuroscience have led to the concept of the ''social brain''. The social brain includes neural processes specialized for processing social information necessary for the recognition of self and others, and interpersonal relationships. Because of its unique behavioral phenotypic features which includes 'hypersociability', Williams syndrome has gained popularity among social cognitive neuroscientists. Individuals with Williams syndrome share the same genetic risk factor for cognitive-behavioral dysfunction utilizing brain imaging to elucidate endophenotype provides us with an unprecendented opportunity to study gene, brain and behavior relationships especially those related to social cognition. In this review, we provide an overview of neuroimaging studies on social cognition in Williams syndrome and discuss the neural basis of the social brain. (author)

The William and Flora Hewlett Foundation | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

The William and Flora Hewlett Foundation. The William and Flora Hewlett Foundation. http://www.hewlett.org/. Think Tank Initiative. This initiative is creating high-quality independent research and policy institutions throughout the developing world. View more. Think Tank Initiative. Growth and Economic Opportunities for ...

Mental Health Problems in Adults with Williams Syndrome

Science.gov (United States)

Stinton, Chris; Elison, Sarah; Howlin, Patricia

2010-01-01

Although many researchers have investigated emotional and behavioral difficulties in individuals with Williams syndrome, few have used standardized diagnostic assessments. We examined mental health problems in 92 adults with Williams syndrome using the Psychiatric Assessment Schedule for Adults with Developmental Disabilities--PAS-ADD (Moss,…

Forest culicinae mosquitoes in the environs of samuel hydroeletric plant, state of Rondônia, Brazil

Directory of Open Access Journals (Sweden)

SLB Luz

1996-08-01

Full Text Available Data on frequency and seasonal distribution of culicinae were recorded in the forest near a recently constructed hydroelectric plant - Samuel, in the State of Rondônia, Brazilian Amazon. Collections were performed almost daily from August 1990 to July 1991, between 6 and 9 p.m., using human bait. A total of 3,769 mosquitoes was collected, representing 21 species, including seven new records for the State of Rondônia. The most frequently collected species were Aedes fulvus (25% and Ae. pennai (12.3%. The highest density for the majority of mosquito species coincided with the rainy season.

34 CFR 685.100 - The William D. Ford Federal Direct Loan Program.

Science.gov (United States)

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false The William D. Ford Federal Direct Loan Program. 685...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION WILLIAM D. FORD FEDERAL DIRECT LOAN PROGRAM Purpose and Scope § 685.100 The William D. Ford Federal Direct Loan Program. (a) Under the William D. Ford...

Congenital heart defects in Williams syndrome.

Science.gov (United States)

Yuan, Shi-Min

2017-01-01

Yuan SM. Congenital heart defects in Williams syndrome. Turk J Pediatr 2017; 59: 225-232. Williams syndrome (WS), also known as Williams-Beuren syndrome, is a rare genetic disorder involving multiple systems including the circulatory system. However, the etiologies of the associated congenital heart defects in WS patients have not been sufficiently elucidated and represent therapeutic challenges. The typical congenital heart defects in WS were supravalvar aortic stenosis, pulmonary stenosis (both valvular and peripheral), aortic coarctation and mitral valvar prolapse. The atypical cardiovascular anomalies include tetralogy of Fallot, atrial septal defects, aortic and mitral valvular insufficiencies, bicuspid aortic valves, ventricular septal defects, total anomalous pulmonary venous return, double chambered right ventricle, Ebstein anomaly and arterial anomalies. Deletion of the elastin gene on chromosome 7q11.23 leads to deficiency or abnormal deposition of elastin during cardiovascular development, thereby leading to widespread cardiovascular abnormalities in WS. In this article, the distribution, treatment and surgical outcomes of typical and atypical cardiac defects in WS are discussed.

Recent paleoseismicity record in Prince William Sound, Alaska, USA

Science.gov (United States)

Kuehl, Steven A.; Miller, Eric J.; Marshall, Nicole R.; Dellapenna, Timothy M.

2017-12-01

Sedimentological and geochemical investigation of sediment cores collected in the deep (>400 m) central basin of Prince William Sound, along with geochemical fingerprinting of sediment source areas, are used to identify earthquake-generated sediment gravity flows. Prince William Sound receives sediment from two distinct sources: from offshore (primarily Copper River) through Hinchinbrook Inlet, and from sources within the Sound (primarily Columbia Glacier). These sources are found to have diagnostic elemental ratios indicative of provenance; Copper River Basin sediments were significantly higher in Sr/Pb and Cu/Pb, whereas Prince William Sound sediments were significantly higher in K/Ca and Rb/Sr. Within the past century, sediment gravity flows deposited within the deep central channel of Prince William Sound have robust geochemical (provenance) signatures that can be correlated with known moderate to large earthquakes in the region. Given the thick Holocene sequence in the Sound ( 200 m) and correspondingly high sedimentation rates (>1 cm year-1), this relationship suggests that sediments within the central basin of Prince William Sound may contain an extraordinary high-resolution record of paleoseismicity in the region.

Emotional Responsivity in Young Children with Williams Syndrome

Science.gov (United States)

Fidler, Debbie J.; Hepburn, Susan L.; Most, David E.; Philofsky, Amy; Rogers, Sally J.

2007-01-01

The hypothesis that young children with Williams syndrome show higher rates of emotional responsivity relative to other children with developmental disabilities was explored. Performance of 23 young children with Williams syndrome and 30 MA-matched children with developmental disabilities of nonspecific etiologies was compared on an adaptation of…

Malformations vasculaires au cours du syndrome de Williams ...

African Journals Online (AJOL)

Le syndrome de Williams-Beuren est une maladie génétique rare, il associe classiquement une dysmorphie faciale assez spécifique, des malformations cardiovasculaires et un profil neuropsychologique particulier. Nous rapportons les observations de trois enfants atteints du syndrome de Williams-Beuren en insistant ...

William Carlos Williams’ cubism: The sensory dimension

Directory of Open Access Journals (Sweden)

J-L Kruger

1995-05-01

Full Text Available In this article the cubism of the American poet William Carlos Williams is discussed as a product of sensory elements combined with techniques derived from the work of the visual artists associated with this style. Through the study o f a number of poems written in the period between 1917 and 1923 it is shown that Williams employs the cubist intersection of sensory planes in particular to create a sensory dimension that not only renews the traditions and mode of poetry, but also reveals the cubist concern with the defamiliarization and foregrounding of fragments of everyday experiences. Ultimately the article is an attempt to indicate Williams’ incorporation o f a sensual dimension in creating a style that achieves modernist presentation revealing an independence from both traditional literary and visual styles.

Infantile ictal apneas in a child with williams-beuren syndrome.

Science.gov (United States)

Myers, Kenneth A; McLeod, D Ross; Bello-Espinosa, Luis

2013-02-01

Williams-Beuren syndrome is a genetic disorder rarely associated with seizures. The few described cases of Williams-Beuren syndrome and epilepsy have primarily involved infantile spasms and deletions extending beyond the common deletion region for this disorder. We present the case of a 5-week-old child with ictal apneas and typical Williams-Beuren syndrome deletion. Diagnosis was challenging, because the child had cardiac, respiratory, and gastrointestinal abnormalities typically associated with Williams-Beuren syndrome, which are also associated with cyanotic episodes. The results of interictal electroencephalography were normal, illustrating that prolonged electroencephalography is often essential in evaluation of suspected ictal apneas. Seizure freedom was achieved with carbamazepine. Sudden death is seen in Williams-Beuren syndrome, and this case raises the question whether some of these cases may be related to ictal apneas and could potentially be preventable with appropriate pharmaceutical intervention. Copyright © 2013 Elsevier Inc. All rights reserved.

Northern gas: Williams petrochemical feasibility study

Energy Technology Data Exchange (ETDEWEB)

Chappell, D. [Williams Energy Canada, Calgary, AB (Canada)

2002-07-01

Williams Energy is a company that is involved in the following fields: gas pipelines, exploration and production, midstream, refining, petrochemical, power, and marketing and trading. The author provides an overview of the global and Canadian infrastructure before proceeding to discuss Arctic gas, which is viewed by Williams Energy as necessary. It favors the Alaska Highway route with a consortium for project development. Williams performed a petrochemical study to determine the feasibility of a petrochemical complex utilizing natural gas liquid from an Arctic gas pipeline. The scope of the study encompassed facilities (extraction plant, cracker, polyolefins plant), size (world scale, approximately 2 billion pounds per year), and location (Fairbanks or Alberta). The study led to the following findings: (1) review of several scenarios for both locations, (2) complex to produce two grades of polyethylene, (3) feedstock cost favors Alaska, (4) construction costs lower in Alberta, (5) and the primary market for the Alaska complex would be northeast Asia, while the primary market for the Alberta location would be the United States. It was determined that both options would be viable, however Alberta was favored due to the polyethylene forecast. The challenges still being faced by Williams include low frac spread, market inefficiencies, empress volumes, carbon dioxide, and fuel and electricity cost. Each of these challenges is discussed separately. The author concludes by indicating that incremental ethane is available, carbon dioxide issues need resolution, and Alberta and Alaska are attractive for Arctic ethane petrochemical production. figs.

The Political Reading of the Bible and an Application to Thomas Hobbes’s Interpretation of the Book of Samuel

Directory of Open Access Journals (Sweden)

Jorge Alfonso

2013-12-01

Full Text Available The article is an introduction to the political reading of the Bible. Jewish federalism is shown as the paradigm of modern contractualism. The author refers to the right interpretation of the Bible onthe basis of the works of Daniel J. Elazar, Max Kadushin y Eric Voegelin. At the end, as an example, the author critizes Hobbes’s interpretation of the Books of Samuel, which is controversial for not taking into account essential aspects of Biblical hermeneutics.

Celiac disease in patients with Williams-Beuren syndrome.

Science.gov (United States)

Mıhçı, Ercan; Nur, Banu Güzel; Berker-Karaüzüm, Sibel; Yılmaz, Aygen; Artan, Reha

2015-01-01

Celiac disease is an autoimmune, gastrointestinal disorder characterized by intolerance to the dietary grain protein gluten. An increased prevalence of celiac disease has been reported in Down syndrome and Turner syndrome, but there has been only few previous reports with respect to the association of celiac disease in Williams-Beuren syndrome. The aim of this study was to evaluate the frequency of celiac disease in our 24 Williams-Beuren syndrome patients. Gastrointestinal problems and celiac disease symptoms of patients were noted. All patients were analyzed by the titer of tissue transglutaminases IgA and IgG. HLA genotyping and intestinal biopsy was performed to the patients with positive serology. We also performed gluten free diet in the presence of compatible symptoms, serology, HLA genotyping and intestinal biopsy. In our study, two patients had positive tTG antibodies, but only one had positive biopsy finding for celiac disease. The frequency of celiac disease in patients with Williams-Beuren syndrome was estimated as 1/24 (4.1%). Though the number of participants in this study was limited, the results show that the frequency of celiac disease is higher in Williams-Beuren syndrome compared to the general population. We suggest that a high suspicion and testing for celiac disease should be recommended at certain intervals in all cases with Williams-Beuren syndrome to detect the cause of growth retardation and gastrointestinal problems.

Williams Syndrome and 15q Duplication: Coincidence versus Association.

Science.gov (United States)

Khokhar, Aditi; Agarwal, Swashti; Perez-Colon, Sheila

2017-01-01

Williams syndrome is a multisystem disorder caused by contiguous gene deletion in 7q11.23, commonly associated with distinctive facial features, supravalvular aortic stenosis, short stature, idiopathic hypercalcemia, developmental delay, joint laxity, and a friendly personality. The clinical features of 15q11q13 duplication syndrome include autism, mental retardation, ataxia, seizures, developmental delay, and behavioral problems. We report a rare case of a girl with genetically confirmed Williams syndrome and coexisting 15q duplication syndrome. The patient underwent treatment for central precocious puberty and later presented with primary amenorrhea. The karyotype revealed 47,XX,+mar. FISH analysis for the marker chromosome showed partial trisomy/tetrasomy for proximal chromosome 15q (15p13q13). FISH using an ELN -specific probe demonstrated a deletion in the Williams syndrome critical region in 7q11.23. To our knowledge, a coexistence of Williams syndrome and 15q duplication syndrome has not been reported in the literature. Our patient had early pubertal development, which has been described in some patients with Williams syndrome. However, years later after discontinuing gonadotropin-releasing hormone analogue treatment, she developed primary amenorrhea.

Colour discrimination and categorisation in Williams syndrome

OpenAIRE

Farran, E. K.; Cranwell, M. B.; Alvarez, J.; Franklin, A.

2013-01-01

Individuals with Williams syndrome (WS) present with impaired functioning of the dorsal visual stream relative to the ventral visual stream. As such, little attention has been given to ventral stream functions in WS. We investigated colour processing, a predominantly ventral stream function, for the first time in nineteen individuals with Williams syndrome. Colour discrimination was assessed using the Farnsworth-Munsell 100 hue test. Colour categorisation was assessed using a match-to-sample ...

76 FR 44893 - Prince William Sound Resource Advisory Committee

Science.gov (United States)

2011-07-27

... DEPARTMENT OF AGRICULTURE Forest Service Prince William Sound Resource Advisory Committee AGENCY: Forest Service, USDA. ACTION: Notice of meeting. SUMMARY: The Prince William Sound Resource Advisory... District, 145 Forest Station Road, Girdwood, AK; Prince Willam Sound Community College, 303 Lowe Street...

33 CFR 165.1704 - Prince William Sound, Alaska-regulated navigation area.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Prince William Sound, Alaska... District § 165.1704 Prince William Sound, Alaska-regulated navigation area. (a) The following is a... Hinchinbrook Light to Schooner Rock Light, comprising that portion of Prince William Sound between 146°30′ W...

Florence Jessie Mac Williams

Indian Academy of Sciences (India)

CPMGIKAlBGE-340/2003-05. Resonance - January 2005. Licenced to post WPP No.6 RT Nagar Postoffice. Florence Jessie Mac Williams. (1917 - 1990). Registered with Registrar of Newspapers in India vide Regn. No. 66273/96. ISSN 0971-8044. Price per copy: Rs 40.

Mailability v. the Crusader: Williams v. O'Brien.

Science.gov (United States)

Simmons, Charles E.

The issues of prior restraint and press censorship are examined in this paper, which focuses on the 1970 Williams v. O'Brien court case. The paper discusses the litigation, in which Robert F. Williams, as an American citizen living in Peking, China, sued the United States Postmaster General over the banning of the May 1967 issue of "The…

David Owen WILLIAMS

CERN Multimedia

2006-01-01

Lidy Williams-Oonk and her children Mark & Marietta, being unable to thank everybody individually, would like to express their sincere thanks to friends and colleagues at CERN and abroad for their great help and support, their messages and flowers, as well as their donations to the Ligue Genevoise contre le Cancer, on the death of their beloved husband and father.

[Clinical value of CT-guided high frequency-induced thermotherapy as a treatment for intrahepatic cholangiocarcinoma].

Science.gov (United States)

Fan, Wei-Jun; Zhang, Liang; Gu, Yang-Kui; Wang, Li-Gang; Ouyang, Yu-Shu

2008-07-01

To evaluate the therapeutic effect of CT-guided high frequency-induced thermotherapy (HiTT) for intrahepatic cholangiocarcinoma. Seventeen patients of intrahepatic cholangiocarcinoma with 21 lesions underwent comprehensive treatment with HiTT as the principle approach. As to the patients with obstructive jaundice, percutaneous trans-hepatic cholangial drainage (PTCD) or bile duct endoprosthesis placement was performed first to improve the liver function, then HiTT was performed; and patients without obstructive jaundice underwent CT-guided HiTT directly, 1-2 weeks later, chemotherapy was given for 4 - 6 courses. CT scan 1 week after HiTT showed a short-term achievement rate of 100% (17/17), and the single puncture in situ ablation rate was 76.1% (16/21). The average life span in the near future was 13.5 months. The adverse effects included topo-bleeding, pain after procedure, liver function damage, defervescence, etc. All the patients recovered after symptomatic treatment. The clinical value of CT-guided HiTT for intrahepatic cholangiocarcinoma is obvious.

77 FR 19301 - Prince William Sound Regional Citizens' Advisory Council Charter Renewal

Science.gov (United States)

2012-03-30

... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2012-0099] Prince William Sound Regional... Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the activities...

Interaction with William Carnall

International Nuclear Information System (INIS)

Judd, Brian R.

2005-01-01

A personal account is given of interaction with William T. Carnall during the period 1977-1988, when I made regular visits to the Argonne National Laboratory to discuss the theoretical background to the spectroscopic work he was carrying out on the lanthanides and actinides

Global and local music perception in children with Williams syndrome.

Science.gov (United States)

Deruelle, Christine; Schön, Daniele; Rondan, Cécilie; Mancini, Josette

2005-04-25

Musical processing can be decomposed into the appreciation of global and local elements. This global/local dissociation was investigated with the processing of contour-violated and interval-violated melodies. Performance of a group of 16 children with Williams syndrome and a group of 16 control children were compared in a same-different task. Control participants were more accurate in detecting differences in the contour-violated than in the interval-violated condition while Williams syndrome individuals performed equally well in both conditions. This finding suggests that global precedence may occur at an early perceptual stage in normally developing children. In contrast, no such global precedence is observed in the Williams syndrome population. These data are discussed in the context of atypical cognitive profiles of individuals with Williams syndrome.

Intracranial arteries in individuals with the elastin gene hemideletion of Williams syndrome.

Science.gov (United States)

Wint, D P; Butman, J A; Masdeu, J C; Meyer-Lindenberg, A; Mervis, C B; Sarpal, D; Morris, C A; Berman, K F

2014-01-01

Williams syndrome, a rare genetic disorder with a striking neurobehavioral profile characterized by extreme sociability and impaired visuospatial construction abilities, is caused by a hemideletion that includes the elastin gene, resulting in frequent supravavular aortic stenosis and other stenotic arterial lesions. Strokes have been reported in Williams syndrome. Although the extracranial carotid artery has been studied in a sample of patients with Williams syndrome, proximal intracranial arteries have not. Using MRA, we studied the intracranial vessels in 27 participants: 14 patients with Williams syndrome (age range, 18-44 years; mean age, 27.3 ± 9.1; 43% women) and 13 healthy control participants with similar age and sex distribution (age range, 22-52 years; mean age, 33.4 ± 7.6; 46% women). All participants with Williams syndrome had hemideletions of the elastin gene. Blinded to group allocation or to any other clinical data, a neuroradiologist determined the presence of intracranial vascular changes in the 2 groups. The Williams syndrome group and the healthy control group had similar patency of the proximal intracranial arteries, including the internal carotid and vertebral arteries; basilar artery; and stem and proximal branches of the anterior cerebral artery, MCA, and posterior cerebral arteries. The postcommunicating segment of the anterior cerebral artery was longer in the Williams syndrome group. Despite the elastin haploinsufficiency, the proximal intracranial arteries in Williams syndrome preserve normal patency.

[Association between Williams syndrome and adrenal insufficiency].

Science.gov (United States)

Rchachi, Meryem; Larwanou, Maazou Mahamane; El Ouahabi, Hanan; Ajdi, Farida

2017-01-01

Williams syndrome is a developmental disorder including dysmorphia, cardiovascular malformations and a specific neuropsychological profile together with other associated disorders. We report the case of a 17-year old girl, born of a non-inbred marriage, with Williams syndrome discovered during an assessment of degree of failure to thrive. Its association with primary adrenal insufficiency makes it unique. Diagnosis is confirmed by cytogenetic and molecular analysis. Its management consists of the implementation of treatment for adrenal insufficiency associated with a clinico-biological monitoring.

White matter integrity deficits in prefrontal-amygdala pathways in Williams syndrome.

Science.gov (United States)

Avery, Suzanne N; Thornton-Wells, Tricia A; Anderson, Adam W; Blackford, Jennifer Urbano

2012-01-16

Williams syndrome is a neurodevelopmental disorder associated with significant non-social fears. Consistent with this elevated non-social fear, individuals with Williams syndrome have an abnormally elevated amygdala response when viewing threatening non-social stimuli. In typically-developing individuals, amygdala activity is inhibited through dense, reciprocal white matter connections with the prefrontal cortex. Neuroimaging studies suggest a functional uncoupling of normal prefrontal-amygdala inhibition in individuals with Williams syndrome, which might underlie both the extreme amygdala activity and non-social fears. This functional uncoupling might be caused by structural deficits in underlying white matter pathways; however, prefrontal-amygdala white matter deficits have yet to be explored in Williams syndrome. We used diffusion tensor imaging to investigate prefrontal-amygdala white matter integrity differences in individuals with Williams syndrome and typically-developing controls with high levels of non-social fear. White matter pathways between the amygdala and several prefrontal regions were isolated using probabilistic tractography. Within each pathway, we tested for between-group differences in three measures of white matter integrity: fractional anisotropy (FA), radial diffusivity (RD), and parallel diffusivity (λ(1)). Individuals with Williams syndrome had lower FA, compared to controls, in several of the prefrontal-amygdala pathways investigated, indicating a reduction in white matter integrity. Lower FA in Williams syndrome was explained by significantly higher RD, with no differences in λ(1), suggestive of lower fiber density or axon myelination in prefrontal-amygdala pathways. These results suggest that deficits in the structural integrity of prefrontal-amygdala white matter pathways might underlie the increased amygdala activity and extreme non-social fears observed in Williams syndrome. Copyright © 2011 Elsevier Inc. All rights reserved.

Discovering Structure in Auditory Input: Evidence from Williams Syndrome

Science.gov (United States)

Elsabbagh, Mayada; Cohen, Henri; Karmiloff-Smith, Annette

2010-01-01

We examined auditory perception in Williams syndrome by investigating strategies used in organizing sound patterns into coherent units. In Experiment 1, we investigated the streaming of sound sequences into perceptual units, on the basis of pitch cues, in a group of children and adults with Williams syndrome compared to typical controls. We showed…

Dental management of patient with Williams Syndrome - A case report.

Science.gov (United States)

Wong, Daniel; Ramachandra, Srinivas Sulugodu; Singh, Ashish Kumar

2015-01-01

Williams syndrome is a multisystemic rare genetic disorder caused by deletion of 26-28 genes in the long arm of chromosome 7. It is characterized by developmental and physical abnormalities including congenital cardiovascular abnormalities, mental retardation, neurological features, growth deficiency, genitourinary manifestations, gastrointestinal problems, musculoskeletal problems, unique behavioral characteristics, and dental problems. Dental abnormalities include malocclusion, hypodontia, malformed teeth, taurodontism, pulp stones, increased space between teeth, enamel hypoplasia, and high prevalence of dental caries. Authors report a 17-year-old female patient with underlying Williams syndrome. Oral features and problems seen in the patient are listed. Malocclusion and screwdriver shaped teeth were noticed. Generalized widening of the periodontal ligament space with vital teeth was seen. This finding has not been reported in cases of Williams syndrome earlier. Precautions taken during dental treatment in patients with Williams syndrome are also discussed.

75 FR 16159 - Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) Charter Renewal

Science.gov (United States)

2010-03-31

... DEPARTMENT OF HOMELAND SECURITY Coast Guard [USCG-2010-0121] Prince William Sound Regional... the Prince William Sound Regional Citizens' Advisory Council (PWSRCAC) as an alternative voluntary advisory group for Prince William Sound, Alaska. This certification allows the PWSRCAC to monitor the...

No limite do silêncio: a cena mínima de Samuel Beckett

Directory of Open Access Journals (Sweden)

Fernando Mesquita de Faria

2014-07-01

Full Text Available http://dx.doi.org/10.5007/2176-8552.2013n16p133 O artigo pretende demonstrar, por reconhecimento, a apropriação do silêncio na dramaturgia de Samuel Beckett. As múltiplas funções e as possibilidades de articulação dramatúrgicas tornam o silêncio tão importante quanto os sons e seu estudo passa a ser essencial para compreendermos os aspectos sonoro-musicais que envolvem a obra do autor, sobretudo por virem associadas a uma linguagem verbal. A estrutura elíptica das suas peças, a exploração sonora de palavras e frases, a escassez de cenários e objetos cênicos, somados ao silêncio, podem produzir um efeito sinestésico no leitor/espectador e são indícios que nos levam a uma reflexão, servindo como álibi para melhor decifrarmos a obra beckettiana.

Was Samuel Butler Mainly Right About Evolution? Part I

Directory of Open Access Journals (Sweden)

Murray Code

2013-07-01

Full Text Available Samuel Butler, a contemporary critic of Charles Darwin, proffered an alternative, vitalistic account of evolution. At the same time, he put into question all modern naturalistic treatments of this fundamental idea which presuppose that evolution is mainly a scientific problem. On the contrary, Butler in effect insists, this extremely vague idea calls for not an `explanation' but rather a fairly comprehensive, plausible story that helps elucidate an inherently complex idea. Butler can thus be read as outlining an anthropomorphic metaphorics that evokes a living Cosmos wherein it might be possible to do justice to the problem which Darwin left unresolved---the problem of heredity. In this picture of the Cosmos Butler links the fundamental notion of organization not to the allegedly universal and immutable `laws of nature,' as the moderns would have it, but rather to dynamically evolving relationships between only more or less stable habits. The variations in extant habits that emergence elicits are moreover the products of quasi-intelligent responses to new challenges from the environment. For Butler follows Lamarck in holding that all organisms possess powers capable of responding to felt needs and/or desires to make alterations in the habits (or instincts that characterize their modes of existence. He thus in the end effectively bequeaths to his readers a challenge to extend and amplify, if possible, his outline of a promising metaphysical imaginary that can take into account some highly unorthodox conjectures.

Anderson, Prof. Basil Williams

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1964 Honorary. Anderson, Prof. Basil Williams. Date of birth: 3 July 1901. Date of death: 24 February 1984. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

Series, Prof. George William

Indian Academy of Sciences (India)

Home; Fellowship. Fellow Profile. Elected: 1984 Honorary. Series, Prof. George William. Date of birth: 22 February 1920. Date of death: 2 January 1995. YouTube; Twitter; Facebook; Blog. Academy News. IAS Logo. 29th Mid-year meeting. Posted on 19 January 2018. The 29th Mid-year meeting of the Academy will be held ...

Fin de partida de Samuel Beckett: La soberanía del lenguaje y el juego metateatral

Directory of Open Access Journals (Sweden)

Carolina Brncic

2014-05-01

Full Text Available El artículo analiza Fin de partida de Samuel Beckett como obra metateatral. Para abordar el problema del género se examinan cuatro enfoques críticos relevantes: la teoría de Martin Esslin sobre el Teatro del Absurdo, la interpretación de Theodor Adorno como drama de la descomposición, la lectura de Christoph Menke como una tragedia de la representación y la propuesta de Lionel Abel sobre el metateatro. A partir de la definición señalada por Abel, se analiza la obra atendiendo a dos dimensiones paradigmáticas: la noción de juego representacional como drama autorreflexivo y la soberanía del lenguaje como soporte dramático.

The use of emotions in narratives in Williams syndrome.

Science.gov (United States)

Van Herwegen, Jo; Aznar, Ana; Tenenbaum, Harriet

2014-01-01

Although individuals with Williams syndrome are very sociable, they tend to have limited contact and friendships with peers. In typically developing children the use of positive emotions (e.g., happy) has been argued to be related to peer relationships and popularity. The current study investigated the use and development of emotion words in Williams syndrome using cross-sectional developmental trajectories and examined children's use of different types of emotion words. Nineteen children with Williams syndrome (WS) and 20 typically developing (TD) children matched for chronological age told a story from a wordless picture book. Participants with WS produced a similar number of emotion words compared to the control group and the use of emotion words did not change when plotted against chronological age or vocabulary abilities in either group. However, participants with WS produced more emotion words about sadness. Links between emotion production and friendships as well as future studies are discussed. After reading this article, readers will be able to: explain the development of positive and negative emotions in Williams syndrome and recognize that emotion production is atypical in this population. Copyright © 2014 Elsevier Inc. All rights reserved.

33 CFR 167.1701 - In Prince William Sound: Precautionary areas.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: Precautionary areas. 167.1701 Section 167.1701 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1701 In Prince William Sound...

A MacWilliams Identity for Convolutional Codes : The General Case

NARCIS (Netherlands)

Gluesing-Luerssen, Heide; Schneider, Gert

A MacWilliams Identity for convolutional codes will be established. It makes use of the weight adjacency matrices of the code and its dual, based on state space realizations (the controller canonical form) of the codes in question. The MacWilliams Identity applies to various notions of duality

Assessing Post Conflict State Building Efforts

Science.gov (United States)

2013-03-01

Develop a global partnership for development Target: Develop further an open, rule-based, predictable, non-discriminatory trading and finance system...Beginner’s Guide to Nation-Building (Santa Monica, CA: Rand Corporation ), 2007, xvii. 15 Samuel Berger, Brent Scowcroft, and William L. Nash, “In...The Beginner’s Guide, xxi. 25 Richard A. Berk and Peter H. Rossi, Thinking About Program Evaluation 2, (Thousand Oaks, CA: Sage Publications, 1999

[Hermann Samuel Reimarus' theory of "modes of life" and "drives"].

Science.gov (United States)

Cheung, Tobias

2006-01-01

This essay focuses on Hermann Samuel Reimarus' (1694-1768) theory of "modes of life" and natural "drives" or "tendencies" (Triebe) in Allgemeine Betrachtungen über die Triebe der Thiere, hauptsdchlich über ihre Kunsttriebe (1760). Reimarus combines the notion of a systemic, organized inner order of organs, in which "functions" and corporeal dispositions correspond to each other, with a system of regulated "actions" of individual organic bodies. These "actions" rely on a "basic drive" (Grundtrieb) of "self-preservation", that Reimarus differentiates into "mechanic drives" (mechanische Triebe), "imagination drives" (Vorstellungstriebe) und "voluntary drives" (willkiirliche Triebe). Voluntary drives are again divided into "affection-drives" (Affectentriebe) and "art-drives" (Kunsttriebe). Mechanic drives automatically initiate and sustain physiological processes of the system of organs, imagination drives establish transitions between sense perception, imagination, memory, and recognition, and art-drives regulate, as schemes or "m odels" which imply some degree of skill, "action" (Handlung)-based relations between individual organic bodies and their environments. Further on, humans possess a specific art-drive, based on "reason" (Vernunft), that is not naturally determined as a goal-directed "action": While the "modes of life" of animals are perfect in themselves in combining systems of drives and organic dispositions, humans are perfectible living beings with the faculty of "reflection". Plants are for Reimarus not living beings, because their existence relies only on "mechanical drives" without a central acting entity of perceptions.

Probed Serial Recall in Williams Syndrome: Lexical Influences on Phonological Short-Term Memory

Science.gov (United States)

Brock, Jan; McCormack, Teresa; Boucher, Jill

2005-01-01

Williams syndrome is a genetic disorder that, it has been claimed, results in an unusual pattern of linguistic strengths and weaknesses. The current study investigated the hypothesis that there is a reduced influence of lexical knowledge on phonological short-term memory in Williams syndrome. Fourteen children with Williams syndrome and 2…

78 FR 28953 - William D. Ford Federal Direct Loan Program

Science.gov (United States)

2013-05-16

.... Ford Federal Direct Loan Program; Interim Final Rule #0;#0;Federal Register / Vol. 78, No. 95... [Docket ID ED-2013-OPE-0066] RIN 1840-AD13 William D. Ford Federal Direct Loan Program AGENCY: Office of... Secretary amends the William D. Ford Federal Direct Loan Program (Direct Loan Program) regulations to...

Pursuing the Panderer: An Analysis of "United States v. Williams"

Science.gov (United States)

McGrain, Patrick N.; Moore, Jennifer L.

2010-01-01

In May 2008, the Supreme Court addressed whether the government can regulate the ownership and distribution of virtual child pornography. "U.S. v. Williams" marked the first time the Court directly addressed the concept of pandering virtual child pornography. This article examines the Court's decision in "U.S. v. Williams" and…

Prince William Sound, Alaska ESI: INDEX

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

Using novel control groups to dissect the amygdala's role in Williams syndrome.

Science.gov (United States)

Thornton-Wells, Tricia A; Avery, Suzanne N; Blackford, Jennifer Urbano

2011-07-01

Williams syndrome is a neurodevelopmental disorder with an intriguing behavioral phenotype-hypersociability combined with significant non-social fears. Previous studies have demonstrated abnormalities in amygdala function in individuals with Williams syndrome compared to typically-developing controls. However, it remains unclear whether the findings are related to the atypical neurodevelopment of Williams syndrome, or are also associated with behavioral traits at the extreme end of a normal continuum. We used functional magnetic resonance imaging (fMRI) to compare amygdala blood-oxygenation-level-dependent (BOLD) responses to non-social and social images in individuals with Williams syndrome compared to either individuals with inhibited temperament (high non-social fear) or individuals with uninhibited temperament (high sociability). Individuals with Williams syndrome had larger amygdala BOLD responses when viewing the non-social fear images than the inhibited temperament control group. In contrast, when viewing both fear and neutral social images, individuals with Williams syndrome did not show smaller amygdala BOLD responses relative to the uninhibited temperament control group, but instead had amygdala responses proportionate to their sociability. These results suggest heightened amygdala response to non-social fear images is characteristic of WS, whereas, variability in amygdala response to social fear images is proportionate to, and might be explained by, levels of trait sociability.

76 FR 1187 - Application for Recertification of Prince William Sound Regional Citizens' Advisory Council

Science.gov (United States)

2011-01-07

... Prince William Sound Regional Citizens' Advisory Council AGENCY: Coast Guard, DHS. ACTION: Notice of... on, the application for recertification submitted by the Prince William Sound Regional Citizen's... advisory group in lieu of a Regional Citizens' Advisory Council for Prince William Sound, Alaska. This...

Dreamers in dialogue: evolution, sex and gender in the utopian visions of William Morris and William Henry Hudson

Directory of Open Access Journals (Sweden)

Caterina Novák

2013-12-01

Full Text Available The aim of this article is to explore the parallels between two late-nineteenth-century utopias,William Henry Hudsons A Crystal Age (1882 and William Morriss News from Nowhere (1891. Itaims to explore how these two works respond to the transition from a kinetic to a static conception ofutopia that under pressure from evolutionary and feminist discourses took place during the period.Particular focus lies on the way in which this is negotiated through the depiction of evolution, sexuality,and gender roles in the respective novels, and how the depiction of these disruptive elements may workas a means of ensuring the readers active engagement in political, intellectual and emotional terms.

A case of William's syndrome associated peripheral pulmonary arterial stenosis

International Nuclear Information System (INIS)

Jung, Kyung Hwa; Hwang, Mi Soo; Kim, Sun Yong; Chang, Jae Chun; Park, Bok Hwan

1988-01-01

William's syndrome, in order to more completely delineate the total spectrum of the disorder, indicates that 'infantile hypercalcemia', 'peculiar facies' and 'supravalvular aortic stenosis.' In has other many vascular anomalies, such as peripheral pulmonary arterial stenosis, coronary arterial stenosis, celiac arterial stenosis, and renal aterial stenosis. Only 32% of the patients have evidence of supravalvular aortic stenosis. And it is very rare disease entity that has been reported rarely in Korea. Recently authors experienced a case that was questioned William's syndrome with peripheral pulmonary arterial stenosis, clinically and preliminary radiologically and this case was confirmed by operation. Here we report a case of William's syndrome with peripheral pulmonary arterial stenosis and reviewed literatures

A MacWilliams Identity for Convolutional Codes: The General Case

OpenAIRE

Gluesing-Luerssen, Heide; Schneider, Gert

2008-01-01

A MacWilliams Identity for convolutional codes will be established. It makes use of the weight adjacency matrices of the code and its dual, based on state space realizations (the controller canonical form) of the codes in question. The MacWilliams Identity applies to various notions of duality appearing in the literature on convolutional coding theory.

Learning by observation: insights from Williams syndrome.

Science.gov (United States)

Foti, Francesca; Menghini, Deny; Mandolesi, Laura; Federico, Francesca; Vicari, Stefano; Petrosini, Laura

2013-01-01

Observing another person performing a complex action accelerates the observer's acquisition of the same action and limits the time-consuming process of learning by trial and error. Observational learning makes an interesting and potentially important topic in the developmental domain, especially when disorders are considered. The implications of studies aimed at clarifying whether and how this form of learning is spared by pathology are manifold. We focused on a specific population with learning and intellectual disabilities, the individuals with Williams syndrome. The performance of twenty-eight individuals with Williams syndrome was compared with that of mental age- and gender-matched thirty-two typically developing children on tasks of learning of a visuo-motor sequence by observation or by trial and error. Regardless of the learning modality, acquiring the correct sequence involved three main phases: a detection phase, in which participants discovered the correct sequence and learned how to perform the task; an exercise phase, in which they reproduced the sequence until performance was error-free; an automatization phase, in which by repeating the error-free sequence they became accurate and speedy. Participants with Williams syndrome beneficiated of observational training (in which they observed an actor detecting the visuo-motor sequence) in the detection phase, while they performed worse than typically developing children in the exercise and automatization phases. Thus, by exploiting competencies learned by observation, individuals with Williams syndrome detected the visuo-motor sequence, putting into action the appropriate procedural strategies. Conversely, their impaired performances in the exercise phases appeared linked to impaired spatial working memory, while their deficits in automatization phases to deficits in processes increasing efficiency and speed of the response. Overall, observational experience was advantageous for acquiring competencies

Learning by observation: insights from Williams syndrome.

Directory of Open Access Journals (Sweden)

Francesca Foti

Full Text Available Observing another person performing a complex action accelerates the observer's acquisition of the same action and limits the time-consuming process of learning by trial and error. Observational learning makes an interesting and potentially important topic in the developmental domain, especially when disorders are considered. The implications of studies aimed at clarifying whether and how this form of learning is spared by pathology are manifold. We focused on a specific population with learning and intellectual disabilities, the individuals with Williams syndrome. The performance of twenty-eight individuals with Williams syndrome was compared with that of mental age- and gender-matched thirty-two typically developing children on tasks of learning of a visuo-motor sequence by observation or by trial and error. Regardless of the learning modality, acquiring the correct sequence involved three main phases: a detection phase, in which participants discovered the correct sequence and learned how to perform the task; an exercise phase, in which they reproduced the sequence until performance was error-free; an automatization phase, in which by repeating the error-free sequence they became accurate and speedy. Participants with Williams syndrome beneficiated of observational training (in which they observed an actor detecting the visuo-motor sequence in the detection phase, while they performed worse than typically developing children in the exercise and automatization phases. Thus, by exploiting competencies learned by observation, individuals with Williams syndrome detected the visuo-motor sequence, putting into action the appropriate procedural strategies. Conversely, their impaired performances in the exercise phases appeared linked to impaired spatial working memory, while their deficits in automatization phases to deficits in processes increasing efficiency and speed of the response. Overall, observational experience was advantageous for

O ADULTÉRIO DE DAVI E BETSABÉIA: LEITURA FEMINISTA E TÉCNICA NARRATIVA EM 2SAMUEL 11

Directory of Open Access Journals (Sweden)

Leonardo Pessoa da Silva Pinto

2017-08-01

Full Text Available RESUMO: A leitura feminista da Bíblia faz parte da pluralidade de métodos e abordagens utilizadas no campo dos estudos bíblicos nas últimas décadas. Esse artigo estuda a relação entre interpretação feminista e outros métodos exegéticos por meio da comparação entre as leituras feministas da história de Davi e Betsa­béia em 2 Samuel 11 e outros estudos de Análise Narrativa. O estudo atento das técnicas narrativas usadas nesta excelente narrativa ajuda a evitar incompreensões por parte do intérprete mais concentrado em questões de gênero. A conclusão é que os princípios narrativos centrais na técnica usada pelo narrador desta história desautorizam interpretações mais radicais dos papéis de Davi e de Betsabéia no episódio do adultério.ABSTRACT: The feminist reading of the biblical texts is part of the plurality of methods and approaches used in biblical scholarship in recent decades. This ar­ticle studies the relationship between feminist interpretation and other exegetical methods by comparing the feminist readings of the David and Bathsheba story in 2Samuel 11 to other studies of Narrative Analysis. The careful study of the narrative techniques used in this fine narrative helps to prevent miscomprehen­sions from the interpreter more focused on questions of gender. The conclusion is that the core narrative principles worked by the narrator of this story disallows the more radical interpretations of David and Bathsheba’s roles in the episode of the adultery.

On Reading Poems: Visual & Verbal Icons in William Carlos Williams' «Landscape With The Fall Of Icarus»

Directory of Open Access Journals (Sweden)

Irene R. Fairley

1981-09-01

Full Text Available Williams' admiration for Brueghel's landscape is coded in structural and stylistic correspondences between the poem and the painting. Structures in the poem have effects analogous to the use of devices of color, line, foregrounding in the painting. The poem, like the painting, presents a «neutral» scene but subtly insures the reader's involvement. Further, Williams draws a visual statement so that graphic features suggest a global image isomorphic with the motif of descent. Features of the poem, such as line and clause length, syntactic construction, semantic coherence, are discussed as factors that contribute to rapid glancing and increase readability. A study of readers shows their sensitivity to graphic features including the poem's shape, and corroborates the importance of stylistic features.

Digital Logic and Reconfigurable Interconnects Using Aluminum Gallium Arsenide Electro-Optic Fredkin Gates

Science.gov (United States)

1994-06-01

electron microscope (SEM) ispection; Carol Isbil for metallizatlon; Wayland Williams for test circuit design and fabrication; and Samuel Adams and...Patterson Air Force Base, OH, Private Conversations, (1990-1994). 156. M. Heiblum, E. E. Mendez and L. Osterling, "Growth by Molecular Beam Epitaxy...and Characterization of High Purity GaAs and AIGaAs," Journal of ADDlied Physics, Vol. 54, 6982, (1983). 157. M. Heiblum, E. E. Mendez and L. Osterling

Interview: William and Barbara Christopher.

Science.gov (United States)

Teaching Exceptional Children, 1986

1986-01-01

Asserting that the biggest mistake educators can make is to set themselves up as experts vis-a-vis parents as amateurs, Barbara and William Christopher emphasize the importance of continued education for the autistic individual and relate their experiences with the educational community as they sought help for their autistic son. (JC)

78 FR 11857 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

Science.gov (United States)

2013-02-20

...; Comment Request; William D. Ford Federal Direct Loan Program (DL) Regulations AGENCY: Department of... in response to this notice will be considered public records. Title of Collection: William D. Ford.... Abstract: The William D. Ford Federal Direct Loan Program regulations cover areas of program administration...

Rorty, Williams, and Davidson: Skepticism and Metaepistemology

Directory of Open Access Journals (Sweden)

Christopher Ranalli

2013-07-01

Full Text Available We revisit an important exchange on the problem of radical skepticism between Richard Rorty and Michael Williams. In his contribution to this exchange, Rorty defended the kind of transcendental approach to radical skepticism that is offered by Donald Davidson, in contrast to Williams’s Wittgenstein-inspired view. It is argued that the key to evaluating this debate is to understand the particular conception of the radical skeptical problem that is offered in influential work by Barry Stroud, a conception of the skeptical problem which generates metaepistemological ramifications for anti-skeptical theories. In particular, we argue that, contra Williams, Rorty’s view that Davidson was offering a theoretical diagnosis of radical skepticism can be consistently maintained with his transcendental approach.

Opium as a Literary Stimulant: The Case of Samuel Taylor Coleridge.

Science.gov (United States)

Vickers, Neil

2015-01-01

In our era, the idea of a stimulant is synonymous with its biochemical properties. A stimulant, we think, is a substance that enhances the activity of the central and peripheral nervous systems. But in the eighteenth century, a new family of theories about the workings of stimulants took shape, based on exciting but erroneous assumptions. Proponents of these theories thought that many more diseases were "nervous" in origin than had previously been supposed. They hoped that the workings of the "nervous power" could be aided by the judicious use of stimulants and narcotics. Practitioners working within this broad "neuropathological" paradigm equated the workings of stimulation with those of gravity. Stimulation, they believed, was a kind of master principle in nature. Some hoped it would help refound medicine on Newtonian, mathematical lines. For patients, the most visible legacy of the neuropathological revolution was the abandonment of bloodletting or "cupping" and the increasingly widespread use of opium and alcohol in medical treatments. In this chapter, I explore the career of one of the most famous writers of the Romantic era, Samuel Taylor Coleridge (1772-1834) who had the misfortune to live through this therapeutic revolution. I describe the circumstances under which he came to take opiates and the development of his opinions about their effect on him. © 2015 Elsevier Inc. All rights reserved.

Music and Anxiety in Williams Syndrome: A Harmonious or Discordant Relationship?

Science.gov (United States)

Dykens, Elisabeth M.; Rosner, Beth A.; Ly, Tran; Sagun, Jaclyn

2005-01-01

In this two-part study, we assessed musical involvements in two samples of persons with Williams syndrome compared to others with mental retardation and also related musicality to anxiety and fears in Study 2. Relative to others with mental retardation, those with Williams syndrome were more likely to take music lessons, play an instrument, and…

Prince William Sound, Alaska ESI: HYDRO (Hydrology)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

Prince William Sound, Alaska ESI: INVERT (Invertebrates)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

Who Was the Real William Shakespeare?

Science.gov (United States)

Edwards, Michael Todd

2009-01-01

This article highlights a project that encourages students to connect reading and mathematics instruction by using a data analysis approach. Students analyze sonnets from statistical, literary, and historical points of view in an effort to uncover the true identity of William Shakespeare. (Contains 10 figures.)

Mr. William Shakespeare and the Internet.

Science.gov (United States)

Reeves, Barbara

2000-01-01

Describes resources and links on a Web site entitled "Mr. William Shakespeare and the Internet," with suggestions for using them with students. Highlights include: historical context; impact of events/situations on works; motivational/preparatory lessons; reading and understanding Shakespeare; analysis of works; language; assessing other…

MacWilliams Identity for M-Spotty Weight Enumerator

Science.gov (United States)

Suzuki, Kazuyoshi; Fujiwara, Eiji

M-spotty byte error control codes are very effective for correcting/detecting errors in semiconductor memory systems that employ recent high-density RAM chips with wide I/O data (e.g., 8, 16, or 32bits). In this case, the width of the I/O data is one byte. A spotty byte error is defined as random t-bit errors within a byte of length b bits, where 1 le t ≤ b. Then, an error is called an m-spotty byte error if at least one spotty byte error is present in a byte. M-spotty byte error control codes are characterized by the m-spotty distance, which includes the Hamming distance as a special case for t =1 or t = b. The MacWilliams identity provides the relationship between the weight distribution of a code and that of its dual code. The present paper presents the MacWilliams identity for the m-spotty weight enumerator of m-spotty byte error control codes. In addition, the present paper clarifies that the indicated identity includes the MacWilliams identity for the Hamming weight enumerator as a special case.

[Vascular malformations in the Williams-Beuren syndrome: report of three new cases].

Science.gov (United States)

Sator, Hicham; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Rhouni, Fatima Ezzahra; Benjouad, Ibitihale; Dafiri, Rachida; Chat, Latifa

2016-01-01

The Williams-Beuren syndrome is a rare genetic disease. It combines classically specific facial dysmorphism, cardiovascular malformations and specific neuropsychological profile. We report three cases of Williams-Beuren syndrome in children with particular emphasis on vascular abnormalities observed on CT angiography and MR angiography.

Samuel A. Mudd, MD, physician-farmer, University of Maryland School of Medicine class of 1856.

Science.gov (United States)

Harding, Richard K

2012-12-01

America is in the midst of experiencing the sesquicentennial of the Civil War. We do so with some ambivalence knowing that the war forged a great union and ended slavery but also caused the deaths of more than 600,000 fellow citizens. Samuel A. Mudd, MD, University of Maryland School of Medicine class of 1856, was a man of this time. As a physician-farmer in Southern Maryland, he was a highly respected physician, a slave owner, and a devout citizen. The Civil War (1861-1865) would alter his life in ways few could have imagined. This article looks at his background, his education, his work as a physician-farmer, and his dramatic rise to national attention and infamy. Convicted by a military tribunal and imprisoned for his "crimes," he was able to partially redeem himself using his medical skills and professionalism. Mudd was a man of his time. And what a time it was.

AMS Days: "the results are phenomenal"

CERN Multimedia

2015-01-01

Following the conclusion of the successful AMS Days at CERN (see here), we sat down with leading minds in space science and particle physics to discuss their thoughts on the recent positron-excess results as well as the future of the AMS physics programme.   Samuel Ting, AMS spokesperson: Roberto Battiston, President of the Italian Space Agency (ASI): William H. Gerstenmaier, Human Exploration and Operations Directorate, NASA: Edward C. Stone (Caltech), Voyager 1 and 2 principal investigator:

Las lenguas indígenas argentinas como objeto de colección. Notas acerca de los estudios lingüísticos de Samuel A. Lafone Quevedo a fines del siglo XIX

Directory of Open Access Journals (Sweden)

Farro, Máximo

2013-08-01

Full Text Available This article analyzes the indigenous language classification efforts carried out by Samuel Alexander Lafone Quevedo towards the end of the 19th century, paying special attention to the context of his production. In order to do so, his collection practices, the organization of the linguistic data, the cooperation relationships he established with correspondents and the activities that were carried out in the institutions he was a member of are taken into account.En este artículo se analizan los trabajos de clasificación de las lenguas indígenas desarrollados por Samuel Alexander Lafone Quevedo hacia fines del siglo XIX, prestando especial atención a su contexto de producción. Para ello se toman en consideración las prácticas de obtención y organización de los datos lingu..sticos, las relaciones de cooperación que estableció con corresponsales y las actividades desarrolladas en los espacios institucionales de los que formó parte.

Stranger Danger Awareness in Williams Syndrome

Science.gov (United States)

Riby, D. M.; Kirk, H.; Hanley, M.; Riby, L. M.

2014-01-01

Background: The developmental disorder Williams syndrome (WS) is characterised by a distinctive cognitive profile and an intriguing social phenotype. Individuals with the disorder are often highly social engaging with familiar and unfamiliar people and once in an interaction they often show subtle abnormalities of social behaviour. Atypically…

33 CFR 164.43 - Automatic Identification System Shipborne Equipment-Prince William Sound.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Automatic Identification System Shipborne Equipment-Prince William Sound. 164.43 Section 164.43 Navigation and Navigable Waters COAST GUARD... Automatic Identification System Shipborne Equipment—Prince William Sound. (a) Until December 31, 2004, each...

“Spiegel im Spiegel” Uma análise psicanalítica da trilogia de Samuel Beckett, pela teoria de Wilfred Bion

OpenAIRE

Vilhena, Manuel Lampreia

2009-01-01

Dissertação de Mestrado apresentada ao Instituto Superior de Psicologia Aplicada para obtenção de grau de Mestre na especialidade de Psicologia Clínica. A psicanálise estabeleceu desde cedo uma relação com a literatura, logo pela mão do seu fundador Sigmund Freud. Este trabalho tem como objectivo fazer uma leitura psicanalítica da trilogia de Samuel Beckett, Molloy, Malone está a morrer e O Inominável. Para tal recorre a não só nome centrais da psicanálise como Freud, Klein, Bi...

N-acetylcysteine for neuropsychiatric symptoms in a woman with Williams syndrome.

Science.gov (United States)

Pineiro, Mildred Lopez; Roberts, Antoinette M; Waxler, Jessica L; Mullett, Jennifer E; Pober, Barbara R; McDougle, Christopher J

2014-11-01

Williams syndrome is a relatively rare genetic disorder caused by the hemizygous microdeletion of a region in chromosome 7q11.23. Individuals with Williams syndrome typically present with a highly social, overfriendly, and empathic personality. Comorbid medical and neuropsychiatric disorders are common. Reports of effective pharmacological treatment of associated neuropsychiatric disorders are limited. The authors describe the successful treatment of interfering anger, aggression, and hair-pulling with N-acetylcysteine in a 19-year-old woman with Williams syndrome. The neuropsychiatric symptoms emerged 1 week following an upper gastrointestinal endoscopy, for which fentanyl, midazolam, and propofol were used as anesthetics. The patient's treatment course and hypothesized mechanisms underlying the clinical presentation and symptom resolution are described. © The Author(s) 2014.

Fading-Figure Tracing in Williams Syndrome

Science.gov (United States)

Nagai, Chiyoko; Inui, Toshio; Iwata, Makoto

2011-01-01

Williams syndrome (WS) is a neurodevelopmental disorder characterized by severe impairment of visuospatial abilities. Figure-drawing abilities, which are thought to reflect visuospatial abilities, have yet to be fully investigated in WS. The purpose of the present study was to clarify whether drawing abilities differ between WS individuals and…

77 FR 43276 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

Science.gov (United States)

2012-07-24

...; William D. Ford Federal Direct Loan Program General Forbearance Request SUMMARY: Borrowers who receive loans through the William D. Ford Federal Direct Loan Program will use this form to request forbearance... considered public records. Title of Collection: William D. Ford Federal Direct Loan Program General...

Seasonal distribution of Dall's porpoise in Prince William Sound, Alaska

Science.gov (United States)

Moran, John R.; O'Dell, Matthew B.; Arimitsu, Mayumi L.; Straley, Janice M.; Dickson, Danielle M. S.

2018-01-01

Dall's porpoise, Phocoenoides dalli, are a conspicuous predator in the Prince William Sound ecosystem, yet there has been little effort directed towards monitoring this species since the 1980s, prior to the Exxon Valdez oil spill. We used vessel-based surveys to examine the seasonal distribution of Dall's porpoise in the waters of Prince William Sound during eight years from 2007 to 2015. Over the course of 168 days and 15,653 km of survey effort, 921 Dall's porpoise were encountered in 210 groups. We estimate an encounter rate of 0.061 porpoise/km traveled or 1 porpoise encountered for every 16.5 km traveled. Dall's porpoise were found throughout the year in Prince William Sound, and used a wide range of habitats, including those not considered typical of the species, such as bays, shallow water, and nearshore waters. Dall's porpoise seasonally shifted their center of distribution from the western passages in fall to the bays of the eastern Sound in winter and spring. Dall's porpoises were widely dispersed throughout the Sound in summer. We identified potential Dall's porpoise habitat (depth, slope, and distance from shore) within Prince William Sound using generalized additive models (GAM). Dall's porpoise were found in deeper water during summer and in shallowest water during spring. We propose that their use of novel habitats is a function of reduced predation risk associated with the decline of their main predator, killer whales (Orcinus orca), following the Exxon Valdez oil spill, and the presence of overwintering and spawning Pacific herring (Clupea pallasii). While the size of the Dall's porpoise population within Prince William Sound remains unknown, our encounter rates were lower than those reported in the 1970s. Their high metabolic rate and ubiquitous presence makes them one of the more important, yet understudied, forage fish predators in the region.

Williams-Beuren syndrome associated with single kidney and nephrocalcinosis: a case report.

Science.gov (United States)

Abidi, Kamel; Jellouli, Manel; Ben Rabeh, Rania; Hammi, Yousra; Gargah, Tahar

2015-01-01

Williams-Beuren syndrome is a rare neurodevelopmental disorder, characterized by congenital heart defects, abnormal facial features, mental retardation with specific cognitive and behavioral profile, growth hormone deficiency, renal and skeletal anomalies, inguinal hernia, infantile hypercalcaemia. We report a case with Williams-Beuren syndrome associated with a single kidney and nephrocalcinosis complicated by hypercalcaemia. A male infant, aged 20 months presented growth retardation associated with a psychomotor impairment, dysmorphic features and nephrocalcinosis. He had also hypercalciuria and hypercalcemia. Echocardiography was normal. DMSA renal scintigraphy showed a single functioning kidney. The FISH generated one ELN signal in 20 metaphases read and found the presence of ELN deletion, with compatible Williams-Beuren syndrome.

77 FR 47374 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

Science.gov (United States)

2012-08-08

...; William D. Ford Federal Direct Loan (Direct Loan) Program/ Federal Family Loan (FFEL) Program: Deferment... which borrowers in the William D. Ford Federal Direct Loan (Direct Loan) and Federal Family Education... considered public records. Title of Collection: William D. Ford Federal Direct Loan (Direct Loan) Program...

MRI Amygdala Volume in Williams Syndrome

Science.gov (United States)

Capitao, Liliana; Sampaio, Adriana; Sampaio, Cassandra; Vasconcelos, Cristiana; Fernandez, Montse; Garayzabal, Elena; Shenton, Martha E.; Goncalves, Oscar F.

2011-01-01

One of the most intriguing characteristics of Williams Syndrome individuals is their hypersociability. The amygdala has been consistently implicated in the etiology of this social profile, particularly given its role in emotional and social behavior. This study examined amygdala volume and symmetry in WS individuals and in age and sex matched…

Attention to Faces in Williams Syndrome

Science.gov (United States)

Riby, Deborah M.; Jones, Nicola; Brown, Philippa H.; Robinson, Lucy J.; Langton, Stephen R. H.; Bruce, Vicki; Riby, Leigh M.

2011-01-01

Williams syndrome (WS) is associated with distinct social behaviours. One component of the WS social phenotype is atypically prolonged face fixation. This behaviour co-exists with attention difficulties. Attention is multi-faceted and may impact on gaze behaviour in several ways. Four experiments assessed (i) attention capture by faces, (ii)…

Enough room for Williams and IMF? / Paul Beckman

Index Scriptorium Estoniae

Beckman, Paul

1999-01-01

Lõppesid Leedu ja USA energeetikakompanii Williams International läbirääkimised Leedu naftakompleksis osaluse omandamise asjus. IMF uurib Leedu majanduslikku arengut, mida tehing Williamsiga komplitseerib

Whither Sir William?

Directory of Open Access Journals (Sweden)

Stephen J. Greenberg, MSLS, PhD

2017-04-01

Full Text Available There are times when something is simply so familiar that we can no longer see it at all. It can be a story, or a concept, or even a flesh-and-blood person. Familiarity breeds not only contempt, but a kind of invisibility as well. For too many of us, such is the case with Sir William Osler. In his time (1849–1919, many considered him to be one of the greatest practitioners, teachers, and writers ever in the field of medicine. He was instrumental in the founding of the Medical Library Association (MLA and was elected its second president.

ABORDAGEM DIAGNÓSTICA DA SÍNDROME DE WILLIAMS - BEUREN.

OpenAIRE

Santos, Marina Machado

2016-01-01

As anomalias cromossômicas causam fenótipos específicos e complexos resultantes de desequilíbrios na dose normal de genes localizados em um segmento cromossômico específico, sendo responsáveis por 60 % ou mais das síndromes genéticas identificáveis. A Síndrome de Williams-Beuren (SWB) caracteriza-se por anomalias múltiplas e deficiência intelectual, descrita independentemente por Williams et al. (1961) e por Beuren et al. (1962). A SWB consiste em uma doença genética causada pela microdeleção...

Florence Jessie Mac Williams (1917-1990)

Indian Academy of Sciences (India)

Home; Journals; Resonance – Journal of Science Education; Volume 10; Issue 1. Florence Jessie Mac Williams (1917-1990). Featured Scientist Volume 10 Issue 1 January 2005 pp 98-98. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/010/01/0098-0098. Resonance ...

Outcome in Adult Life for People with Williams Syndrome Results from a Survey of 239 Families

Science.gov (United States)

Howlin, P.; Udwin, O.

2006-01-01

BACKGROUND: Although there has been considerable research into the genotype and phenotype of Williams syndrome, there have been relatively few studies of long-term prognosis. As a preliminary to a more detailed investigation of adults with Williams syndrome, a parental questionnaire was distributed to members of the UK Williams Syndrome…

Coronary ostium occlusion by coronary cusp displacement in Williams syndrome.

Science.gov (United States)

Shiohama, Tadashi; Fujii, Katsunori; Ebata, Ryota; Funabashi, Nobusada; Matsumiya, Goro; Saito, Yuko Kazato; Takechi, Fumie; Yonemori, Yoko; Nakatani, Yukio; Shimojo, Naoki

2016-06-01

Williams syndrome is a contiguous gene deletion syndrome resulting from a heterozygous deletion on chromosome 7q11.23, and is characterized by distinctive facial features and supravalvular aortic stenosis (SVAS). This syndrome rarely presents unpredictable cardiac death, and yet, as illustrated in the present case, it is still not possible to predict it, even on close monitoring. We herein describe the case of a 6-year-old Japanese girl with Williams syndrome, who had sudden cardiac collapse due to cardiac infarction after pharyngitis. Cardiac failure followed a critical course that did not respond to catecholamine support or heart rest with extracardiac mechanical support. Although marked coronary stenosis was not present, the left coronary cusp abnormally adhered to the aortic wall, which may synergistically cause coronary ostium occlusion with SVAS. Altered hemodynamic state, even that caused by the common cold, may lead to critical myocardial events in Williams syndrome with SVAS. © 2015 Japan Pediatric Society.

Who Invented the Word Asteroid: William Herschel or Stephen Weston?

Science.gov (United States)

Cunningham, Clifford J.; Orchiston, Wayne

2011-11-01

William Herschel made the first serious study of 1 Ceres and 2 Pallas in the year 1802. He was moved by their dissimilarities to the other planets to coin a new term to distinguish them. For this purpose he enlisted the aid of his good friends William Watson and Sir Joseph Banks. Watson gave him a long list of possible names, which Herschel rejected. With a lifetime of experience classifying and naming newly found objects in nature, Banks became the man both Erasmus Darwin (in 1781) and William Herschel (in 1802) turned to for sage advice in developing a new descriptive language. In the case of Ceres and Pallas, Banks turned the task over to his friend, the noted philologist Stephen Weston, FRS. It has recently been stated by a noted British historian that it was Weston - not Herschel - who coined the term 'asteroid' to collectively describe Ceres and Pallas. This claim is investigated, and parallels are drawn in the use of neologism in astronomy and botany.

The scientific legacy of William Herschel

CERN Document Server

2018-01-01

This book presents a modern scholarly analysis of issues associated with England’s most famous astronomer, William Herschel. The world’s leading experts on Herschel, discoverer of the planet Uranus, here offer their combined wisdom on many aspects of his life and astronomical research. Solar system topics include comets, Earth’s Moon, and the spurious moons of Uranus, all objects whose observation was pioneered by Herschel.  The contributors examine his study of the structure of the Milky Way and an in-depth look at the development of the front view telescopes he built. The popular subject of extraterrestrial life is looked at from the point of view of both William Herschel and his son John, both of whom had an interest in the topic. William’s personal development through the educational system of the late eighteenth-century is also explored, and the wide range of verse and satire in various languages associated with his discoveries is collected here for the first time. Hershel worked at a time of i...

Holocene deposition and megathrust splay fault geometries within Prince William Sound, Alaska

Science.gov (United States)

Finn, S.; Liberty, L. M.; Haeussler, P. J.; Pratt, T. L.

2011-12-01

New high resolution sparker seismic reflection data, in conjunction with reprocessed legacy seismic data, provide the basis for a new fault, fold, and Holocene sediment thickness database for Prince William Sound, Alaska. Additionally, legacy airgun seismic data in Prince William Sound and the Gulf of Alaska tie features on these new sparker data to deeper portions of megathrust splay faults. We correlate regionally extensive bathymetric lineaments within Prince William Sound to megathrust splay faults, such as the ones that ruptured in the 1964 M9.2 earthquake. Lastly, we estimate Holocene sediment thickness within Prince William Sound to better constrain the Holocene fault history throughout the region. We identify three seismic facies related to Holocene, Quaternary, and Tertiary strata that are crosscut by numerous high angle normal faults in the hanging wall of the megathrust splay faults. The crustal-scale seismic reflection profiles show splay faults emerging from 20 km depth between the Yakutat block and North American crust and surfacing as the Hanning Bay and Patton Bay faults. A change in exhumation rates, slip rates, and fault orientation appears near Hinchinbrook that we attribute to differences in subducted slab geometry. Based on our slip rate analysis, we calculate average Holocene displacements of 20 m and 100 m in eastern and western Prince William Sound, respectively. Landward of two splay faults exposed on Montague Island, we observe subsidence, faulting, and landslides that record deformation associated with the 1964 and older megathrust earthquakes.

March 1964 Prince William Sound, USA Images

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Prince William Sound magnitude 9.2 Mw earthquake on March 28, 1964 at 03:36 GMT (March 27 at 5:36 pm local time), was the largest U.S. earthquake ever recorded...

Attentional Disengagement in Adults with Williams Syndrome

Science.gov (United States)

Lense, Miriam D.; Key, Alexandra P.; Dykens, Elisabeth M.

2011-01-01

Williams syndrome (WS) is a neurodevelopmental disorder characterized by a distinctive behavioral and cognitive profile, including widespread problems with attention. However, the specific nature of their attentional difficulties, such as inappropriate attentional allocation and/or poor attentional disengagement abilities, has yet to be…

Sleep-EEG in dizygotic twins discordant for Williams syndrome.

Science.gov (United States)

Bódizs, Róbert; Gombos, Ferenc; Szocs, Katalin; Réthelyi, János M; Gerván, Patrícia; Kovács, Ilona

2014-01-30

Reports on twin pairs concordant and discordant for Williams syndrome were published before, but no study unravelled sleep physiology in these cases yet. We aim to fill this gap by analyzing sleep records of a twin pair discordant for Williams syndrome extending our focus on presleep wakefulness and sleep spindling. We performed multiplex ligation-dependent probe amplification of the 7q11.23 region of a 17 years old dizygotic opposite-sex twin pair discordant for Williams syndrome. Polysomnography of laboratory sleep at this age was analyzed and followed-up after 1.5 years by ambulatory polysomnography. Sleep stages scoring, EEG power spectra and sleep spindle analyses were carried out. The twin brother showed reduced levels of amplification for all of the probes in the 7q11.23 region indicating a typical deletion spanning at least 1.038 Mb between FKBP6 and CLIP2. The results of the twin sister showed normal copy numbers in the investigated region. Lower sleep times and efficiencies, as well as higher slow wave sleep percents of the twin brother were evident during both recordings. Roughly equal NREM, Stage 2 and REM sleep percents were found. EEG analyses revealed state and derivation-independent decreases in alpha power, lack of an alpha spectral peak in presleep wakefulness, as well as higher NREM sleep sigma peak frequency in the twin brother. Faster sleep spindles with lower amplitude and shorter duration characterized the records of the twin brother. Spectra show a striking reliability and correspondence between the two situations (laboratory vs. home records). Alterations in sleep and specific neural oscillations including the alpha/sigma waves are inherent aspects of Williams syndrome.

Auditory Attraction: Activation of Visual Cortex by Music and Sound in Williams Syndrome

Science.gov (United States)

Thornton-Wells, Tricia A.; Cannistraci, Christopher J.; Anderson, Adam W.; Kim, Chai-Youn; Eapen, Mariam; Gore, John C.; Blake, Randolph; Dykens, Elisabeth M.

2010-01-01

Williams syndrome is a genetic neurodevelopmental disorder with a distinctive phenotype, including cognitive-linguistic features, nonsocial anxiety, and a strong attraction to music. We performed functional MRI studies examining brain responses to musical and other types of auditory stimuli in young adults with Williams syndrome and typically…

Florence Jessie MacWilliams (1917-1990)

Indian Academy of Sciences (India)

famous mathematician Oscar Zariski, well known for his work in algebraic geometry, at. Johns Hopkins University, following him to Harvard University to study with him for a year. There was a break in her studies for many years following her marriage in 1941 to. W al ter Mac Williams, an engineer, and the birth and raising of ...

Prince William Sound, Alaska ESI: FISH (Fish Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

Prince William Sound, Alaska ESI: NESTS (Bird Nests)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

William Shakespeare’s“Hamlet”and Oedipus Complex

Institute of Scientific and Technical Information of China (English)

迪丽努尔

2014-01-01

“Hamlet”is one of the great dramas of William Shakespeare. This paper by describing the relationship between Hamlet and his mother, the Ghost and his uncle, tries to approve that Oedipus complex is the main reason of Hamlet’s kil ing his uncle.

De wereld in 18 lessen: Christopher Williams

NARCIS (Netherlands)

Berrebi, S.

2011-01-01

Hij is een echte artist’s artist, de conceptuele fotograaf Christopher Williams. Sinds hij in Duitsland woont en werkt, vindt zijn afgewogen werk, dat de fotografie tegelijk eert en ondervraagt, steeds makkelijker onderdak in Europese kunstinstituten, zoals dit voorjaar bij Museum Dhondt-Dhaenens in

Samuel Lysons and His Circle: Art, Science and the Remains of Roman Britain

Directory of Open Access Journals (Sweden)

Sarah Ann Scott

2013-09-01

Full Text Available This paper critically evaluates the social and intellectual influences which shaped Samuel Lysons’ (1763–1819 interests in the archaeological remains of Roman Britain, and assesses the extent to which his work was innovative. While Romano-British archaeologists have long admired his achievements, there has been no detailed examination of the factors influencing the development of his interests and approach. This paper will outline how Lysons’ social networks, his genuine concern for preserving and recording Romano-British remains, his broad scholarly interests, and the support of an intellectual elite involved with the expansion of national institutions during a period characterized by intense international rivalry, resulted in his exemplary approach to the excavation and publication of the remains of Roman Britain. Scrutiny of newspaper reports, diaries, correspondence, and the previously unpublished contents of his personal library, and an examination of his publications in relation to contemporary Classical and scientific scholarship, shows how and why his work was at the forefront of archaeological scholarship in this period. The results of this study support his reputation as a founding father of Romano-British archaeology and show that both he and his associates deserve far wider recognition of their contributions to the development of archaeology as a whole.

A case of William's syndrome associated peripheral pulmonary arterial stenosis

Energy Technology Data Exchange (ETDEWEB)

Jung, Kyung Hwa; Hwang, Mi Soo; Kim, Sun Yong; Chang, Jae Chun; Park, Bok Hwan [College of Medicine, Yeungam University, Daegu (Korea, Republic of)

1988-06-15

William's syndrome, in order to more completely delineate the total spectrum of the disorder, indicates that 'infantile hypercalcemia', 'peculiar facies' and 'supravalvular aortic stenosis.' In has other many vascular anomalies, such as peripheral pulmonary arterial stenosis, coronary arterial stenosis, celiac arterial stenosis, and renal aterial stenosis. Only 32% of the patients have evidence of supravalvular aortic stenosis. And it is very rare disease entity that has been reported rarely in Korea. Recently authors experienced a case that was questioned William's syndrome with peripheral pulmonary arterial stenosis, clinically and preliminary radiologically and this case was confirmed by operation. Here we report a case of William's syndrome with peripheral pulmonary arterial stenosis and reviewed literatures.

Word-Preserving Arts: Material Inscription, Ekphrasis, and Spatial Form in the Later Work of William Wordsworth

DEFF Research Database (Denmark)

Simonsen, Peter

William Wordsworth, posterity, reading, material inscription, ekphrasis, description, sonnet, portraiture......William Wordsworth, posterity, reading, material inscription, ekphrasis, description, sonnet, portraiture...

Colour discrimination and categorisation in Williams syndrome.

Science.gov (United States)

Farran, Emily K; Cranwell, Matthew B; Alvarez, James; Franklin, Anna

2013-10-01

Individuals with Williams syndrome (WS) present with impaired functioning of the dorsal visual stream relative to the ventral visual stream. As such, little attention has been given to ventral stream functions in WS. We investigated colour processing, a predominantly ventral stream function, for the first time in nineteen individuals with Williams syndrome. Colour discrimination was assessed using the Farnsworth-Munsell 100 hue test. Colour categorisation was assessed using a match-to-sample test and a colour naming task. A visual search task was also included as a measure of sensitivity to the size of perceptual colour difference. Results showed that individuals with WS have reduced colour discrimination relative to typically developing participants matched for chronological age; performance was commensurate with a typically developing group matched for non-verbal ability. In contrast, categorisation was typical in WS, although there was some evidence that sensitivity to the size of perceptual colour differences was reduced in this group. Copyright © 2013 Elsevier Ltd. All rights reserved.

The world in eighteen lessons: Christopher Williams

NARCIS (Netherlands)

Berrebi, S.

2011-01-01

Conceptual photographer Christopher Williams is a real artist's artist. Ever since he moved to Germany, his measured work, which both reveres and examines the art of photography, has more and more easily found its way into European art institutes, such as this spring at Museum Dhondt-Dhaenens in

Analysis of Speech Fluency in Williams Syndrome

Science.gov (United States)

Rossi, Natalia Freitas; Sampaio, Adriana; Goncalves, Oscar F.; Giacheti, Celia Maria

2011-01-01

Williams syndrome (WS) is a neurodevelopmental genetic disorder, often referred as being characterized by dissociation between verbal and non-verbal abilities, although the number of studies disputing this proposal is emerging. Indeed, although they have been traditionally reported as displaying increased speech fluency, this topic has not been…

Attribution of Negative Intention in Williams Syndrome

Science.gov (United States)

Godbee, Kali; Porter, Melanie A.

2013-01-01

People with Williams syndrome (WS) are said to have sociable and extremely trusting personalities, approaching strangers without hesitation. This study investigated whether people with WS are less likely than controls to attribute negative intent to others when interpreting a series of ambiguous pictures. This may, at least partially, explain…

William Barlow and the Determination of Atomic Arrangement in Crystals.

Science.gov (United States)

Mauskopf, Seymour H

2015-04-01

William Barlow (1845-1934) was an important if unconventional scientist, known for having developed the 'closest-packing' atomic models of crystal structure. He resumed an early nineteenth-century tradition of utilizing crystallographical and chemical data to determine atomic arrangements in crystals. This essay recounts Barlow's career and scientific activity in three parts: (a) His place in the tradition of determining atomic arrangement in context of this earlier tradition and of contemporaneous developments of crystallography and chemistry, (b) his unconventional career, and (c) the 'success' of his program to determine atomic arrangements in crystals and its influence on the work of William Lawrence Bragg.

77 FR 63308 - J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint

Science.gov (United States)

2012-10-16

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL12-106-000] J. William Foley Incorporated v. United Illuminating Company; Notice of Complaint Take notice that on October 5...) and 825(e), J. William Foley Incorporated (Complainant) filed a formal complaint against United...

Application of Choi—Williams Reduced Interference Time Frequency Distribution to Machinery Diagnostics

Directory of Open Access Journals (Sweden)

Howard A. Gaberson

1995-01-01

Full Text Available This article discusses time frequency analysis of machinery diagnostic vibration signals. The short time Fourier transform, the Wigner, and the Choi–Williams distributions are explained and illustrated with test cases. Examples of Choi—Williams analyses of machinery vibration signals are presented. The analyses detect discontinuities in the signals and their timing, amplitude and frequency modulation, and the presence of different components in a vibration signal.

Increased overall cortical connectivity with syndrome specific local decreases suggested by atypical sleep-EEG synchronization in Williams syndrome.

Science.gov (United States)

Gombos, Ferenc; Bódizs, Róbert; Kovács, Ilona

2017-07-21

Williams syndrome (7q11.23 microdeletion) is characterized by specific alterations in neurocognitive architecture and functioning, as well as disordered sleep. Here we analyze the region, sleep state and frequency-specific EEG synchronization of whole night sleep recordings of 21 Williams syndrome and 21 typically developing age- and gender-matched subjects by calculating weighted phase lag indexes. We found broadband increases in inter- and intrahemispheric neural connectivity for both NREM and REM sleep EEG of Williams syndrome subjects. These effects consisted of increased theta, high sigma, and beta/low gamma synchronization, whereas alpha synchronization was characterized by a peculiar Williams syndrome-specific decrease during NREM states (intra- and interhemispheric centro-temporal) and REM phases of sleep (occipital intra-area synchronization). We also found a decrease in short range, occipital connectivity of NREM sleep EEG theta activity. The striking increased overall synchronization of sleep EEG in Williams syndrome subjects is consistent with the recently reported increase in synaptic and dendritic density in stem-cell based Williams syndrome models, whereas decreased alpha and occipital connectivity might reflect and underpin the altered microarchitecture of primary visual cortex and disordered visuospatial functioning of Williams syndrome subjects.

Notas no percurso: linguagem musical e Síndrome de Williams/Notes on the way: musical language and Williams Syndrome

Directory of Open Access Journals (Sweden)

Paulo Sérgio Souza Junior

2009-12-01

Full Text Available O presente artigo versa sobre uma síndrome em particular chamada Síndrome de Williams-Beuren. Esta síndrome possui uma relação específica com a música, relação esta que estará no fulcro de nossas preocupações durante as páginas que se seguem. Num primeiro momento faremos uma apresentação da síndrome e de suas singularidades; em seguida nos debruçaremos sobre a especificidade que aqui está em questão, ou seja, a relação da síndrome com o universo sonoro; por fim, traremos um caso com o qual tivemos contato envolvendo a educação musical em contexto da síndrome, e discutiremos a respeito dos elementos que esse contato nos trouxe para pensar essa curiosa e relevante relação entre arte-educação e o desenvolvimento neuropsicológico atípico. The present article is about a particular syndrome, called Williams-Beuren. This syndrome has a very specific relationship with music, which will be at the heart of our concerns over the following pages. Initially we will make a presentation of the syndrome and its singularities. Then we will focus on the uniqueness of the correlation between Williams-Beuren and the musical world. Finally, we will discuss a case which involves musical education in the context of this syndrome, and discuss about the elements, brought by that contact, that are useful to think about this curious and relevant relationship between art education and atypical neuropsychological development.

77 FR 58819 - Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan...

Science.gov (United States)

2012-09-24

... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; William D. Ford... William D. Ford Federal Direct Loan Program will use this form to request forbearance on their loans when... of Collection: William D. Ford Federal Direct Loan Program General Forbearance Request. OMB Control...

77 FR 29988 - Notice of Submission for OMB Review; Federal Student Aid; William D. Ford Federal Direct Loan...

Science.gov (United States)

2012-05-21

... DEPARTMENT OF EDUCATION Notice of Submission for OMB Review; Federal Student Aid; William D. Ford... borrowers in the William D. Ford Federal Direct Loan (Direct Loan) and Federal Family Education Loan (FFEL... of Collection: William D. Ford Federal Direct Loan Program Deferment Request Forms. OMB Control...

Icons of Just Is: Justice, Suffering, and the Artwork of Samuel Bak

Directory of Open Access Journals (Sweden)

Gary A. Phillips

2017-06-01

Full Text Available This paper examines select paintings by Holocaust survivor and painter Samuel Bak from his recent Just Is series. The essay explores ways Bak’s art bears witness to suffering. He creatively interrogates and reanimates the iconic figure of Lady Justice and the biblical principle of the lex talionis (“eye for an eye” in order to fashion alternative icons fit for an age of atrocity and loss. Bak’s artwork gives visual expression to Theodor Adorno’s view of the precariousness of art after Auschwitz. It is art’s responsibility to attend to the burden of real suffering experiences (the burden of the empirical and to think in contradictions, which renders art both adequate and inadequate in standing up against the injustice of other’s suffering. Through inventive juxtaposition of secular and sacred symbols, Bak displays the paradox of representation after the Holocaust and art’s precarious responsibility giving voice to suffering. Bak fashions visual spaces in which barbarity and beauty coincide and collide. He invites viewers into this space and into dialogue about justice’s standing and promises. Do Bak's remade icons of Just Is lament a permanent loss of justice and peace, or do they point tentatively to possibilities of life lived in a damaged world with an alternative Just Is? Bak’s artwork prompts such vexing questions for his viewers to contemplate and leaves them to decide what must be done.

[Dr. Samuel Serge Voronoff (1866-1951) or "the quest for eternal youth"].

Science.gov (United States)

Augier, F; Salf, E; Nottet, J B

1996-01-01

Samuel Serge Voronoff, a French physician and surgeon of Russian origin was the Khédive's personal physician from 1896 to 1910 and the instigator of modern medicine in Egypt. He was later a student and friend of Alexis Carrel as soon as 1910 and directed a service of bone grafts during World War I. Between 1912 and 1949 he published the results of his experimental work at his Voronoff Foundation of the Collège de France and at Grimaldi where he performed homografts of endocrine glands of cattle and corresponding heterografts between great primates and man. Contested since 1922 by his colleagues for his results however histologically confirmed and improved durable, Voronoff who had an audience in the Académie des Sciences will proceed his research with success during the period preceding World War II. He grafted old people in senior homes and Government cattle in Algeria, training followers in Italy and California. In 1939 he gave all his research facilities at the Collège de France to René Leriche (1879-1955) and remained on the American continent until 1945. At that time his theories became obsolete in view of the progress in endocrinology and his laboratories were destroyed during the war. He died in Lausanne in 1951 at 85. The recent epidemics caused by HIV suggests to study the work he performed in the Collège de France.

[The experience of being ill and the physician-patient relationship in Samuel Hahnemann's correspondence with his patients].

Science.gov (United States)

Stolberg, M

1999-01-01

This paper uses on the extensive patient correspondence of Dr. Samuel Hahnemann as the basis for a history of homeopathy from the patients' point of view. The value of these epistolary records is two-fold: first, in order to produce their daily records as requested by Hahnemann, the patients learned to pay attention even to the slightest physical or emotional changes. No other contemporary source from allopathic medicine provides similarly detailed and dense data on the very physical perception of the body and its illnesses. Second, the letters and Hahnemann's answers, as far as they have survived, provide detailed insights into the relationship between the physician and his patients. They help identify, in particular, the strategies used by Hahnemann to maintain his professional dignity, a good level of income, and his patients' trust - even through years of treatment without improvement. The letters also record the patients' response to Hahnemann's unusually authoritarian manners.

Clinical utility of an array comparative genomic hybridization analysis for Williams syndrome.

Science.gov (United States)

Yagihashi, Tatsuhiko; Torii, Chiharu; Takahashi, Reiko; Omori, Mikimasa; Kosaki, Rika; Yoshihashi, Hiroshi; Ihara, Masahiro; Minagawa-Kawai, Yasuyo; Yamamoto, Junichi; Takahashi, Takao; Kosaki, Kenjiro

2014-11-01

To reveal the relation between intellectual disability and the deleted intervals in Williams syndrome, we performed an array comparative genomic hybridization analysis and standardized developmental testing for 11 patients diagnosed as having Williams syndrome based on fluorescent in situ hybridization testing. One patient had a large 4.2-Mb deletion spanning distally beyond the common 1.5-Mb intervals observed in 10/11 patients. We formulated a linear equation describing the developmental age of the 10 patients with the common deletion; the developmental age of the patient with the 4.2-Mb deletion was significantly below the expectation (developmental age = 0.51 × chronological age). The large deletion may account for the severe intellectual disability; therefore, the use of array comparative genomic hybridization may provide practical information regarding individuals with Williams syndrome. © 2014 Japanese Teratology Society.

Shepard Award Winners, Part 2: Dr. Tracie Williams

Centers for Disease Control (CDC) Podcasts

2009-07-29

This podcast highlights the accomplishments of Dr. Tracie Williams, recipient of the prestigious 2009 CDC Charles C. Shepard Award.  Created: 7/29/2009 by Centers for Disease Control and Prevention (CDC).   Date Released: 7/29/2009.

Sir William Jenner (1815-1898) and Queen Victoria.

Science.gov (United States)

Seddon, David; Queen Victoria

2004-08-01

This biographical note outlines the work of Sir William Jenner (1815-1898), court physician 1861-93 and President of the Royal College of Physicians 1881-8. He was the first to distinguish between typhoid and typhus both clinically and pathologically.

The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

Science.gov (United States)

Vandeweyer, Geert; Van der Aa, Nathalie; Reyniers, Edwin; Kooy, R Frank

2012-06-08

Williams-Beuren syndrome is a rare contiguous gene syndrome, characterized by intellectual disability, facial dysmorphisms, connective-tissue abnormalities, cardiac defects, structural brain abnormalities, and transient infantile hypercalcemia. Genes lying telomeric to RFC2, including CLIP2, GTF2I and GTF2IRD1, are currently thought to be the most likely major contributors to the typical Williams syndrome cognitive profile, characterized by a better-than-expected auditory rote-memory ability, a relative sparing of language capabilities, and a severe visual-spatial constructive impairment. Atypical deletions in the region have helped to establish genotype-phenotype correlations. So far, however, hardly any deletions affecting only a single gene in the disease region have been described. We present here two healthy siblings with a pure, hemizygous deletion of CLIP2. A putative role in the cognitive and behavioral abnormalities seen in Williams-Beuren patients has been suggested for this gene on the basis of observations in a knock-out mouse model. The presented siblings did not show any of the clinical features associated with the syndrome. Cognitive testing showed an average IQ for both and no indication of the Williams syndrome cognitive profile. This shows that CLIP2 haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome, nor does it lead to the Williams syndrome cognitive profile. Although contribution of CLIP2 to the phenotype cannot be excluded when it is deleted in combination with other genes, our results support the hypothesis that GTF2IRD1 and GTF2I are the main genes causing the cognitive defects associated with Williams-Beuren syndrome. Copyright © 2012 The American Society of Human Genetics. Published by Elsevier Inc. All rights reserved.

Brief Report: Developing Spatial Frequency Biases for Face Recognition in Autism and Williams Syndrome

Science.gov (United States)

Leonard, Hayley C.; Annaz, Dagmara; Karmiloff-Smith, Annette; Johnson, Mark H.

2011-01-01

The current study investigated whether contrasting face recognition abilities in autism and Williams syndrome could be explained by different spatial frequency biases over developmental time. Typically-developing children and groups with Williams syndrome and autism were asked to recognise faces in which low, middle and high spatial frequency…

Denigrating Carl Rogers: William Coulson's Last Crusade.

Science.gov (United States)

Kirschenbaum, Howard

1991-01-01

Reviews William Coulson's assertions that Carl Rogers, Abraham Maslow, and he initiated the humanistic education field, that Rogers repudiated his philosophy late in life, and that they owe the nation's parents an apology. Argues that these charges are groundless and provides examples and quotations from Rogers' later writings to show how Rogers…

Fears, Hyperacusis and Musicality in Williams Syndrome

Science.gov (United States)

Blomberg, Stefan; Rosander, Michael; Andersson, Gerhard

2006-01-01

The study investigated the prevalence of fear and hyperacusis and the possible connections between fear, hyperacusis and musicality in a Swedish sample of individuals with Williams syndrome (WS). The study included 38 individuals and a cross-sectional design, with no matched control group. Two persons, who knew the participant well, completed a…

Executive Functions in Individuals with Williams Syndrome

Science.gov (United States)

Menghini, D.; Addona, F.; Costanzo, F.; Vicari, S.

2010-01-01

Background: The present study was aimed at investigating working memory (WM) and executive functions capacities in individuals with Williams syndrome (WS) as compared with mental-age matched typically developing (TD) children. Method: In order to serve the study goal, a sizeable battery of tasks tapping WM as well as attention, memory, planning,…

Läbi legendide William Shakespeare'i poole / Maris Peters

Index Scriptorium Estoniae

Peters, Maris

2010-01-01

Tutvustus: Wells, Stanley. Kas on tõsi, et Shakespeare ...? / tõlkinud Maris Peters. Tallinn : Argo, 2010. Raamat William Shakespeare kohta käivatest legendidest, kuuldustest ja teooriatest ning tema teoste autorsusest

William and Caroline Herschel pioneers in late 18th-century astronomy

CERN Document Server

Hoskin, Michael

2013-01-01

This beautifully structured book presents the essentials of William and Caroline Herschel's pioneering achievements in late 18th-century astronomy. Michael Hoskin shows that William Herschel was the first observational cosmologist and one of the first observers to attack the sidereal universe beyond the solar system:Herschel built instruments far better than any being used at the royal observatory. Aided by his sister Caroline, he commenced a great systematic survey that led to his discovery of Uranus in 1781.Unlike observers before him, whose telescopes did not reveal them as astronomical obj

Herbert Hoover and William Shakespeare: Two Writers on Ethics.

Science.gov (United States)

Somers, Margaret L.

1979-01-01

Outlines the ways in which Herbert Hoover and William Shakespeare wrote about professional ethics (for engineers and kings, respectively) using the writing techniques of concreteness, audience awareness, and development by induction. (TJ)

78 FR 45515 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

Science.gov (United States)

2013-07-29

... DEPARTMENT OF EDUCATION [Docket No.: ED-2013-ICCD-0099] Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan Program Repayment Plan Selection Form AGENCY... notice will be considered public records. Title of Collection: William D. Ford Federal Direct Loan...

Psycholinguistic Abilities of Children with Williams Syndrome

Science.gov (United States)

Rossi, Natalia F.; Heinze, Elena Garayzabal; Giacheti, Celia M.; Goncalves, Oscar F.; Sampaio, Adriana

2012-01-01

The objective of this study was to investigate the psycholinguistic abilities of children with Williams syndrome (WS) and typically developing children using the Illinois Test of Psycholinguistic Abilities (ITPA). Performance on the ITPA was analysed in a group with WS (N=20, mean age=8.5 years, SD=1.62) and two typically developing groups,…

78 FR 52169 - Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan...

Science.gov (United States)

2013-08-22

... DEPARTMENT OF EDUCATION [Docket No. ED-2013-ICCD-0109] Agency Information Collection Activities; Comment Request; William D. Ford Federal Direct Loan (Direct Loan) Program Federal Direct PLUS Loan Master... to this notice will be considered public records. Title of Collection: William D. Ford Federal Direct...

Williams syndrome deletions and duplications: Genetic windows to understanding anxiety, sociality, autism, and schizophrenia.

Science.gov (United States)

Crespi, Bernard J; Procyshyn, Tanya L

2017-08-01

We describe and evaluate an integrative hypothesis for helping to explain the major neurocognitive features of individuals with Williams syndrome region deletions and duplications. First, we demonstrate how the cognitive differences between Williams syndrome individuals, individuals with duplications of this region, and healthy individuals parallel the differences between individuals subject to effects of increased or decreased oxytocin. Second, we synthesize evidence showing that variation in expression of the gene GTF2I (General Transcription Factor II-I) underlies the primary social phenotypes of Williams syndrome and that common genetic variation in GTF2I mediates oxytocin reactivity, and its correlates, in healthy populations. Third, we describe findings relevant to the hypothesis that the GTF2I gene is subject to parent of origin effects whose behavioral expression fits with predictions from the kinship theory of genomic imprinting. Fourth, we describe how Williams syndrome can be considered, in part, as an autistic syndrome of Lorna Wing's 'active-but-odd' autism subtype, in contrast to associations of duplications with both schizophrenia and autism. Copyright © 2017 Elsevier Ltd. All rights reserved.

Williams syndrome and mature B-Leukemia: A random association?

Science.gov (United States)

Decimi, Valentina; Fazio, Grazia; Dell'Acqua, Fabiola; Maitz, Silvia; Galbiati, Marta; Rizzari, Carmelo; Biondi, Andrea; Cazzaniga, Giovanni; Selicorni, Angelo

2016-12-01

Williams syndrome (WBS) is a rare neurodevelopmental disorder with specific phenotypic characteristics and cardiac abnormalities, but is not considered as a cancer predisposing condition. However, in rare cases, malignancies have been described in patients with WBS, with hematologic cancer (mainly Burkitt Lymphoma and Acute Lymphoblastic Leukemia) as the most represented. We report here the case of a boy with WS and B-NHL. This is the unique case within the large cohort of patients (n = 117) followed in our institution for long time (mean clinical follow-up, 13 years). We herewith propose that the BCL7B gene, located in the chromosomal region commonly deleted in Williams syndrome, could potentially have a role in this particular association. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

Ischemic Stroke in Williams-Beuren Syndrome: A Case Report

Directory of Open Access Journals (Sweden)

Wei-Der Lee

2009-04-01

Full Text Available A 15-year-old girl was admitted because of an acute onset of facial palsy and right hemiparesis. The patient had a history of moderate mental retardation and developmental delay. On admission, her vital signs were stable, except for high blood pressure. Magnetic resonance imaging demonstrated an infarct involving the left internal capsule and putamen. Because of the patient's young age, an extensive stroke survey was performed. Williams-Beuren syndrome was finally confirmed by fluorescent in situ hybridization. Compared with the previously reported cases, no evidence of cerebral arterial stenosis or cardiac abnormalities was found by noninvasive imaging techniques. Because Williams-Beuren syndrome is a complex, multiple congenital anomaly syndrome with prominent cardiovascular features, regular assessment and antihypertensive treatment are necessary to minimize the lifelong cardiovascular risk in patients with this syndrome.

Experiences of Bullying for Individuals with Williams Syndrome

Science.gov (United States)

Fisher, Marisa H.; Lough, Emma; Griffin, Megan M.; Lane, Laurel A.

2017-01-01

Background: Individuals with intellectual disability experience high rates of bullying, but it is not known how people with specific syndromes, such as Williams syndrome (WS), experience and respond to bullying. Given their behavioral profile, including hypersociability and heightened anxiety, and their risk for experiencing other forms of…

Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndrome.

Science.gov (United States)

Fung, Lawrence K; Quintin, Eve-Marie; Haas, Brian W; Reiss, Allan L

2012-04-01

The overarching goal of this review is to compare and contrast the cognitive-behavioral features of fragile X syndrome (FraX) and Williams syndrome and to review the putative neural and molecular underpinnings of these features. Information is presented in a framework that provides guiding principles for conceptualizing gene-brain-behavior associations in neurodevelopmental disorders. Abnormalities, in particular cognitive-behavioral domains with similarities in underlying neurodevelopmental correlates, occur in both FraX and Williams syndrome including aberrant frontostriatal pathways leading to executive function deficits, and magnocellular/dorsal visual stream, superior parietal lobe, inferior parietal lobe, and postcentral gyrus abnormalities contributing to deficits in visuospatial function. Compelling cognitive-behavioral and neurodevelopmental contrasts also exist in these two disorders, for example, aberrant amygdala and fusiform cortex structure and function occurring in the context of contrasting social behavioral phenotypes, and temporal cortical and cerebellar abnormalities potentially underlying differences in language function. Abnormal dendritic development is a shared neurodevelopmental morphologic feature between FraX and Williams syndrome. Commonalities in molecular machinery and processes across FraX and Williams syndrome occur as well - microRNAs involved in translational regulation of major synaptic proteins; scaffolding proteins in excitatory synapses; and proteins involved in axonal development. Although the genetic variations leading to FraX and Williams syndrome are different, important similarities and contrasts in the phenotype, neurocircuitry, molecular machinery, and cellular processes in these two disorders allow for a unique approach to conceptualizing gene-brain-behavior links occurring in neurodevelopmental disorders.

Anxiety and Repetitive Behaviours in Autism Spectrum Disorders and Williams Syndrome: A Cross-Syndrome Comparison

Science.gov (United States)

Rodgers, Jacqui; Riby, Deborah M.; Janes, Emily; Connolly, Brenda; McConachie, Helen

2012-01-01

Children with Autism Spectrum Disorder or Williams syndrome are vulnerable to anxiety. The factors that contribute to this risk remain unclear. This study compared anxiety in autism spectrum disorder and Williams Syndrome and examined the relationship between repetitive behaviours and anxiety. Thirty-four children with autism and twenty children…

Electrophysiological Correlates of Semantic Processing in Williams Syndrome

Science.gov (United States)

Pinheiro, Ana P.; Galdo-Alvarez, Santaigo; Sampaio, Adriana; Niznikiewicz, Margaret; Goncalves, Oscar F.

2010-01-01

Williams syndrome (WS), a genetic neurodevelopmental disorder due to microdeletion in chromosome 7, has been described as a syndrome with an intriguing socio-cognitive phenotype. Cognitively, the relative preservation of language and face processing abilities coexists with severe deficits in visual-spatial tasks, as well as in tasks involving…

Repetition Priming in Adults with Williams Syndrome: Age-Related Dissociation between Implicit and Explicit Memory

Science.gov (United States)

Krinsky-McHale, Sharon J.; Kittler, Phyllis; Brown, W. Ted; Jenkins, Edmund C.; Devenny, Darlynne A.

2005-01-01

We examined implicit and explicit memory in adults with Williams syndrome. An age-related dissociation was found; repetition priming (reflecting implicit memory) did not show change with age, but free recall (reflecting explicit memory) was markedly reduced. We also compared the performance of adults with Williams syndrome to adults with Down…

Williams syndrome predisposes to vascular stiffness modified by antihypertensive use and copy number changes in NCF1.

Science.gov (United States)

Kozel, Beth A; Danback, Joshua R; Waxler, Jessica L; Knutsen, Russell H; de Las Fuentes, Lisa; Reusz, Gyorgy S; Kis, Eva; Bhatt, Ami B; Pober, Barbara R

2014-01-01

Williams syndrome is caused by the deletion of 26 to 28 genes, including elastin, on human chromosome 7. Elastin insufficiency leads to the cardiovascular hallmarks of this condition, namely focal stenosis and hypertension. Extrapolation from the Eln(+/-) mouse suggests that affected people may also have stiff vasculature, a risk factor for stroke, myocardial infarction, and cardiac death. NCF1, one of the variably deleted Williams genes, is a component of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex and is involved in the generation of oxidative stress, making it an interesting candidate modifier for vascular stiffness. Using a case-control design, vascular stiffness was evaluated by pulse wave velocity in 77 Williams cases and matched controls. Cases had stiffer conducting vessels than controls (PWilliams syndrome. Pulse wave velocity increased with age at comparable rates in cases and controls, and although the degree of vascular stiffness varied, it was seen in both hypertensive and normotensive Williams participants. Use of antihypertensive medication and extension of the Williams deletion to include NCF1 were associated with protection from vascular stiffness. These findings demonstrate that vascular stiffness is a primary vascular phenotype in Williams syndrome and that treatment with antihypertensives or agents inhibiting oxidative stress may be important in managing patients with this condition, potentially even those who are not overtly hypertensive.

Adaptive Functioning in Williams Syndrome: A Systematic Review

Science.gov (United States)

Brawn, Gabrielle; Porter, Melanie

2018-01-01

Literature on the level of adaptive functioning and relative strengths and weaknesses in functioning of individuals with Williams syndrome (WS) was reviewed. The electronic databases PsycINFO, PubMed, Expanded Academic, Web of Science, Scopus and ProQuest were searched electronically for relevant articles and dissertations using the search terms…

Potential Beneficial Effects of Tulbaghia violacea William Henry ...

African Journals Online (AJOL)

Tulbaghia violacea William Henry Harvey (Harv. Alliaceae) is a small bulbous herb belonging to the family Alliaceae. It is used in South Africa to treat fever, colds, asthma, paralysis, and hypertension. Meanwhile, cardiovascular disease accounts for about 30 % of total global death, with most of these deaths occurring in low ...

77 FR 58818 - Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal...

Science.gov (United States)

2012-09-24

... DEPARTMENT OF EDUCATION Notice of Proposed Information Collection Requests; Federal Student Aid; William D. Ford Federal Direct Loan Program Regulations-- Servicemembers Civil Relief Act SUMMARY: Upon a... in response to this notice will be considered public records. Title of Collection: William D. Ford...

Estrutura e significado em "Uma rosa para Emily", de William Faulkner

Directory of Open Access Journals (Sweden)

Carlos Daghlian

2004-01-01

Full Text Available Trata-se de uma análise do consagrado conto "Uma Rosa para Emily", de William Faulkner, voltada para alguns dos principais aspectos de sua estrutura. Após considerarmos o enredo, discutimos a construção das personagens, com destaque para a protagonista, fazendo um levantamento e comentários sobre possíveis fontes de inspiração, destacando, entre outras, aspectos da biografia da poeta Emily Dickinson, a ficção e a poesia de E. A. Poe, romances de Charles Dickens e Henry James, o conto de Sherwood Anderson e a poesia de William Blake, Emily Dickinson, Robert Browning e John Crowe Ransom, acrescentando paralelos com o conto "Bartleby, o escrivão", de Herman Melville. Analisamos, então, o foco narrativo, os símbolos e o significado, ressaltando aqui o desenvolvimento temático da narrativa.This is an analysis of the well-known short story "A Rose for Emily," by William Faulkner, concentrating on some of the main aspects of its structure. A consideration of the plot is followed by a discussion of characterization, with emphasis on the protagonist, by means of a survey and comments on possible sources of inspiration including, among others, aspects of Emily Dickinson's biography, E. A. Poe's fiction and poetry, novels by Charles Dickens and Henry James, Sherwood Anderson's short stories, and the poetry of William Blake, Emily Dickinson, Robert Browning, and John Crowe Ransom, in addition to Herman Melville's short story "Bartleby, the Scrivener." The narrative focus, symbolism and meaning, stressing the thematic development of the narrative, are then analyzed.

Bayesian stock assessment of Pacific herring in Prince William Sound, Alaska.

Science.gov (United States)

Muradian, Melissa L; Branch, Trevor A; Moffitt, Steven D; Hulson, Peter-John F

2017-01-01

The Pacific herring (Clupea pallasii) population in Prince William Sound, Alaska crashed in 1993 and has yet to recover, affecting food web dynamics in the Sound and impacting Alaskan communities. To help researchers design and implement the most effective monitoring, management, and recovery programs, a Bayesian assessment of Prince William Sound herring was developed by reformulating the current model used by the Alaska Department of Fish and Game. The Bayesian model estimated pre-fishery spawning biomass of herring age-3 and older in 2013 to be a median of 19,410 mt (95% credibility interval 12,150-31,740 mt), with a 54% probability that biomass in 2013 was below the management limit used to regulate fisheries in Prince William Sound. The main advantages of the Bayesian model are that it can more objectively weight different datasets and provide estimates of uncertainty for model parameters and outputs, unlike the weighted sum-of-squares used in the original model. In addition, the revised model could be used to manage herring stocks with a decision rule that considers both stock status and the uncertainty in stock status.

Bayesian stock assessment of Pacific herring in Prince William Sound, Alaska.

Directory of Open Access Journals (Sweden)

Melissa L Muradian

Full Text Available The Pacific herring (Clupea pallasii population in Prince William Sound, Alaska crashed in 1993 and has yet to recover, affecting food web dynamics in the Sound and impacting Alaskan communities. To help researchers design and implement the most effective monitoring, management, and recovery programs, a Bayesian assessment of Prince William Sound herring was developed by reformulating the current model used by the Alaska Department of Fish and Game. The Bayesian model estimated pre-fishery spawning biomass of herring age-3 and older in 2013 to be a median of 19,410 mt (95% credibility interval 12,150-31,740 mt, with a 54% probability that biomass in 2013 was below the management limit used to regulate fisheries in Prince William Sound. The main advantages of the Bayesian model are that it can more objectively weight different datasets and provide estimates of uncertainty for model parameters and outputs, unlike the weighted sum-of-squares used in the original model. In addition, the revised model could be used to manage herring stocks with a decision rule that considers both stock status and the uncertainty in stock status.

Neural Correlates of Amusia in Williams Syndrome

OpenAIRE

Lense, Miriam D.; Dankner, Nathan; Pryweller, Jennifer R.; Thornton-Wells, Tricia A.; Dykens, Elisabeth M.

2014-01-01

Congenital amusia is defined by marked deficits in pitch perception and production. Though historically examined only in otherwise typically developing (TD) populations, amusia has recently been documented in Williams syndrome (WS), a genetic, neurodevelopmental disorder with a unique auditory phenotype including auditory sensitivities and increased emotional responsiveness to music but variable musical skill. The current study used structural T1-weighted magnetic resonance imaging and diffus...

76 FR 13667 - Commercial Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe...

Science.gov (United States)

2011-03-14

... Furniture Group, Inc., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Including...., Formerly Known as Falcon Products, Inc., Shelby Williams, Howe and Thonet, Chicago, IL; Amended Certification Regarding Eligibility To Apply for Worker Adjustment Assistance In accordance with Section 223 of...

Report of Some Comets: The Discovery of Uranus and Comets by William, Caroline, and John Herschel

Science.gov (United States)

Pasachoff, Jay M.; Olson, R. J. M.

2011-01-01

We report on the discovery and drawings of comets by William, Caroline, and John Herschel. The first discovery, by William Herschel, in 1781 from Bath, published in the Philosophical Transactions of the Royal Society with the title "Report of a Comet," turned out to be Uranus, the first planet ever discovered, Mercury through Saturn having been known since antiquity. William's sister Caroline was given duties of sweeping the skies and turned out to be a discoverer of 8 comets in her own right, in addition to keeping William's notes. Caroline's comets were discovered from Slough between 1786 and 1797. In the process, we also discuss original documents from the archives of the Royal Society and of the Royal Astronomical Society. We conclude by showing comet drawings that we have recently attributed to John Herschel, including Halley's Comet from 1836, recently located in the Ransom Center of the University of Texas at Austin. Acknowledgments: Planetary astronomy at Williams College is supported in part by grant NNX08AO50G from NASA Planetary Astronomy. We thank Peter Hingley of the Royal Astronomical Society and Richard Oram of the Harry Ransom Center of The University of Texas at Austin for their assistance.

Ethical Life in Kierkegaard and Williams

OpenAIRE

Stocker, Barry

2018-01-01

A discussion of how the criticisms of ethical theory in Søren Kierkegaard and Bernard Williams both reinforce each other and also provide some challenges to each other. Despite Williams’ brief and dismissive encounter with Kierkegaard around the reading of a ancient tragedy, both oppose any tendency to see the characters in those tragedies as lacking in agency. Both are consistently concerned with how the individual struggles for some ethical agency and how no individual can be free of the in...

Prince William Sound, Alaska ESI: M_MAMMAL (Marine Mammal Polygons)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

El Curso Superior de Sintaxis Española de Samuel Gili Gaya: un enfoque transversal

Directory of Open Access Journals (Sweden)

Olalla Martínez

2007-01-01

Full Text Available Curso superior de sintaxis española (Advanced Course in Spanish Syntax (1961, by Samuel Gili Gaya, is a diaphanous example of the cultural richness that was generated at the time of the scientific renovation, which launched the Centro de Estudios Históricos (The Centre for Historical Studies (1909. The work of Gili Gaya is indebted to this renovation, as is demonstrated by the perspective from which the author studies some aspects of language, such as sentence definition, concordance and connectors etc. His transversal focus, not being subject to the limitations of any scientific doctrines, allowed him to produce a realistic description of language. From the outset this objective presented something innovative. Moreover, the same author affirmed that his work pursued educational objectives. Altogether this explains that, sometimes, he takes into account factors that were rarely considered at that time, in Spain, such as communicative context, the role of the author and the reader, the communicative intention, diastratic and diatopic varieties etc. This article wishes to demonstrate, through the use of implicit and explicit sources, and from the epistemological base of this work, that this is one of the most innovative contributions to Spanish grammar of the 20th century, considering the historical and cultural context in which it was published.

WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

Energy Technology Data Exchange (ETDEWEB)

Rothenberg, L. [Memorial Sloan-Kettering Cancer Center (United States)

2015-06-15

Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

WE-G-213-02: The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who Were They and What Did They Do?

International Nuclear Information System (INIS)

Rothenberg, L.

2015-01-01

Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

Edward Christopher Williams and His Impact on Librarianship.

Science.gov (United States)

Latimer, Carlos

Edward Christopher Williams had a major impact on librarianship, not only as the first documented African American to graduate from a library school, but also as a developer of education for librarians and as an active member of the American Library Association (ALA) and the Ohio Library Association. This study used the historical methodology…

Orientation Perception in Williams Syndrome: Discrimination and Integration

Science.gov (United States)

Palomares, Melanie; Landau, Barbara; Egeth, Howard

2009-01-01

Williams Syndrome (WS) is a rare neurodevelopmental disorder, which stems from a genetic deletion on chromosome 7 and causes a profound weakness in visuospatial cognition. Our current study explores how orientation perception may contribute to the visuospatial deficits in WS. In Experiment 1, we found that WS individuals and normal 3-4 year olds…

Health and Social Outcomes in Adults with Williams Syndrome: Findings from Cross-Sectional and Longitudinal Cohorts

Science.gov (United States)

Elison, Sarah; Stinton, Chris; Howlin, Patricia

2010-01-01

Previous studies have investigated trajectories of cognitive, language and adaptive functioning in Williams syndrome (WS) but little is known about how other aspects of the Williams syndrome behavioural phenotype change across the life-span. Therefore, the present study examined age associated changes in a number of different domains of…

Comparison of the acute effects of Tulbaghia violacea William Henry ...

African Journals Online (AJOL)

William Henry Harvey (Alliaceae) on blood pressure and heart rate of ... (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T. ... have similar secondary metabolites and biological ...

ProRisk : risk analysis instrument : developed for William properties

NARCIS (Netherlands)

van Doorn, W.H.W.; Egeberg, Ingrid; Hendrickx, Kristoff; Kahramaner, Y.; Masseur, B.; Waijers, Koen; Weglicka, K.A.

2005-01-01

This report presents a Risk Analysis Instrument developed for William Properties. Based on the analysis, it appears that the practice of Risk Analysis exists within the organization, yet rather implicit. The Risk Analysis Instrument comes with a package of four components: an activity diagram, a

William Ospina y la búsqueda de la franja amarilla

Directory of Open Access Journals (Sweden)

Víctor Valero Bernal

2016-12-01

Full Text Available El objetivo de este artículo es el de analizar el ensayo «Lo que le falta a Colombia» del escritor William Ospina. En este ensayo Ospina profundiza en los principales problemas sociales y políticos que Colombia atravesaba a finales del s. XX así como en las posibles soluciones que podrían adoptarse. Los planteamientos que emplea el escritor colombiano pueden relacionarse con una gran variedad de conceptos propios del ámbito de la política y la sociología. A lo largo de este trabajo mostraremos las analogías existentes entre el análisis de William Ospina y las ideas de pensadores tan alejados en el tiempo como Thomas Hobbes, Rousseau, John Rawls o Charles Tilly.

The work experience of a patient affected by Williams Syndrome: a pilot project at the Bambino Gesù Children's Hospital.

Science.gov (United States)

De Lorenzo, Francesca; Macchiaiolo, Marina; Carlevaris, Carla Maria; Bartuli, Andrea

2017-05-31

A new approach has been designed at the Bambino Gesù Children's Hospital in Rome aimed at increasing empowerment in Williams Syndrome individuals through tutor-assisted work activities. Williams Syndrome is characterized by a combination of distinguishing physical traits, congenital anomalies, intellectual disabilities, and a specific developmental profile.This manuscript describes the case of a Williams Syndrome patient.There are only few papers in the scientific literature describing interventions targeting improvement in the quality of life of adult Williams Syndrome individuals. Therefore, this experience may prove useful to several patients, their families, and the experts helping them.We described an example of intervention aimed at guiding and facilitating a Williams Syndrome patient within a work environment, taking into consideration the peaks and valleys of these individuals' specific abilities.Based on our results, we also stressed the need to promote a set of projects and initiatives aimed at enhancing as much as possible self-sufficiency and psycho-affective balance in Williams Syndrome individuals, in order to protect their dignity and self-esteem.

La Fondation William et Flora Hewlett | IDRC - International ...

International Development Research Centre (IDRC) Digital Library (Canada)

La Fondation William et Flora Hewlett. http://www.hewlett.org/ · What we do · Funding · Resources · About IDRC. Knowledge. Innovation. Solutions. Careers · Contact Us · Site map. Sign up now for IDRC news and views sent directly to your inbox each month. Subscribe · Copyright · Open access policy · Privacy policy ...

Advocating for Inclusion of Children with Williams Syndrome

Science.gov (United States)

Self, Michelle A.

2010-01-01

The purpose of this study was to describe and explore the experience of inclusion of students with Williams syndrome, a rare genetic condition of a microdeletion on chromosome 7 which has medical, behavior, and cognitive issues. The study was conducted by gaining an understanding from the parents' point of view. The study was twofold. First, the…

A Conversation with William A. Fowler Part II

Science.gov (United States)

Greenberg, John

2005-06-01

Physicist William A.Fowler initiated an experimental program in nuclear astrophysics after World War II. He recalls here the Steady State versus Big Bang controversy and his celebrated collaboration with Fred Hoyle and Geoffrey and Margaret Burbidge on nucleosynthesis in stars. He also comments on the shift away from nuclear physics in universities to large accelerators and national laboratories.

[William Harvey revisited ].

Science.gov (United States)

Steinke, Hubert

2015-07-01

William Harvey's discovery of the circulation of the blood is often described as a product of the Scientific Revolution of the Seventeenth Century. Modern research has, however, shown thatHarvey followed the Aristotelian research tradition and thus tried to reveal the purpose of the organs through examination of various animals. His publication of 1628 has to be read as an argument of natural philosophy, or, more precisely, as a series of linked observations, experiments and philosophical reasonings from which the existence of circulation has to be deduced as a logical consequence. Harvey did not consider experiments as superior to philosophical reasoning nor intended he to create a new system of medicine. He believed in the vitality of the heart and the blood and rejected Francis Bacon's empirism and the mechanistic rationalism of Descartes. Harvey's contribution and originality lied less in his single observations and experiments but in the manner how he linked them with critical reasoning and how he accepted, presented and defended the ensuing radical findings.

Approach to downstream planning for nearshore response and sensitive areas protection outside Prince William Sound, Alaska

International Nuclear Information System (INIS)

DeCola, E.G.; Robertson, T.L.; Robertson, R.; Banta, J.

2004-01-01

This study assessed the need for an oil spill response plan for downstream coastal communities that could be affected by oil spilled from tankers travelling in Prince William Sound, Alaska. For the purpose of oil spill contingency planning, the State of Alaska has been divided into the Kodiak and Cook Inlet sub-areas that are at risk for downstream impacts from a Prince William Sound oil spill. The 1989 Exxon Valdez oil spill provided an example of a worst-case scenario oil spill from a tanker in Prince William Sound, but the oil spill planning system that has evolved in Alaska does not adequately plan for on oil spill that originates in one sub-area of the state, but impacts other sub-areas in the downstream spill path. This study analyzed the gaps that exist in the current response planning system in the Prince William Sound, Cook Inlet and Kodiak sub-areas. A method was proposed to improve the existing response plans so that emergency response teams are better prepared to manage cross-boundary oil spills originating in Prince William Sound. The proposed method focuses on nearshore response and sensitive areas protection for coastlines and communities that are at risk for oil spills from a tanker travelling the Trans-Alaska Pipeline System (TAPS). 11 refs., 3 figs

Characterisation of Sleep Problems in Children with Williams Syndrome

Science.gov (United States)

Annaz, Dagmara; Hill, Catherine M.; Ashworth, Anna; Holley, Simone; Karmiloff-Smith, Annette

2011-01-01

Sleep is critical to optimal daytime functioning, learning and general health. In children with established developmental disorders sleep difficulties may compound existing learning difficulties. The purpose of the present study was to evaluate the prevalence and syndrome specificity of sleep problems in Williams syndrome (WS), a…

78 FR 63464 - William D. Ford Federal Direct Loan Program Repayment Plan Selection Form; Extension of Public...

Science.gov (United States)

2013-10-24

... DEPARTMENT OF EDUCATION William D. Ford Federal Direct Loan Program Repayment Plan Selection Form; Extension of Public Comment Period; Correction AGENCY: Department of Education. ACTION: Correction notice... entitled, ``William D. Ford Federal Direct Loan Program Repayment Plan Selection Form''. ED is extending...

Gender Attribution and Gender Agreement in French Williams Syndrome

Science.gov (United States)

Boloh, Yves; Ibernon, Laure; Royer, Stephanie; Escudier, Frederique; Danillon, Aurelia

2009-01-01

Previous studies on grammatical gender in French individuals with Williams syndrome (WS) have led to conflicting findings and interpretations regarding keys abilities--gender attribution and gender agreement. New production data from a larger SW sample (N = 24) showed that gender attribution scores in SW participants exactly mirrored those of…

Visually Guided Step Descent in Children with Williams Syndrome

Science.gov (United States)

Cowie, Dorothy; Braddick, Oliver; Atkinson, Janette

2012-01-01

Individuals with Williams syndrome (WS) have impairments in visuospatial tasks and in manual visuomotor control, consistent with parietal and cerebellar abnormalities. Here we examined whether individuals with WS also have difficulties in visually controlling whole-body movements. We investigated visual control of stepping down at a change of…

A Diagnosis to Consider in an Adult Patient with Facial Features and Intellectual Disability: Williams Syndrome.

Science.gov (United States)

Doğan, Özlem Akgün; Şimşek Kiper, Pelin Özlem; Utine, Gülen Eda; Alikaşifoğlu, Mehmet; Boduroğlu, Koray

2017-03-01

Williams syndrome (OMIM #194050) is a rare, well-recognized, multisystemic genetic condition affecting approximately 1/7,500 individuals. There are no marked regional differences in the incidence of Williams syndrome. The syndrome is caused by a hemizygous deletion of approximately 28 genes, including ELN on chromosome 7q11.2. Prenatal-onset growth retardation, distinct facial appearance, cardiovascular abnormalities, and unique hypersocial behavior are among the most common clinical features. Here, we report the case of a patient referred to us with distinct facial features and intellectual disability, who was diagnosed with Williams syndrome at the age of 37 years. Our aim is to increase awareness regarding the diagnostic features and complications of this recognizable syndrome among adult health care providers. Williams syndrome is usually diagnosed during infancy or childhood, but in the absence of classical findings, such as cardiovascular anomalies, hypercalcemia, and cognitive impairment, the diagnosis could be delayed. Due to the multisystemic and progressive nature of the syndrome, accurate diagnosis is critical for appropriate care and screening for the associated morbidities that may affect the patient's health and well-being.

Anaesthesia-related haemodynamic complications in Williams syndrome patients: a review of one institution's experience.

Science.gov (United States)

Olsen, M; Fahy, C J; Costi, D A; Kelly, A J; Burgoyne, L L

2014-09-01

Williams syndrome is a genetic disorder associated with cardiac pathology, including supravalvular aortic stenosis and coronary artery stenosis. Sudden cardiac death has been reported in the perioperative period and attributed to cardiovascular pathology. In this retrospective audit, case note and anaesthetic records were reviewed for all confirmed Williams syndrome patients who had received an anaesthetic in our institution between July 1974 and November 2009. There were a total of 108 anaesthetics administered in 29 patients. Twelve of the anaesthetics (11.1%) were associated with cardiac complications including cardiac arrest in two cases (1.85%). Of the two cardiac arrests, one patient died within the first 24 hours postanaesthetic and the other patient survived, giving an overall mortality of 0.9% (3.4%). We conclude that Williams syndrome confers a significant anaesthetic risk, which should be recognised and considered by clinicians planning procedures requiring general anaesthesia.

50 CFR Figure 4 to Subpart E of... - Prince William Sound Rural and Non-Rural Areas

Science.gov (United States)

2010-10-01

... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Prince William Sound Rural and Non-Rural Areas 4 Figure 4 to Subpart E of Part 300 Wildlife and Fisheries INTERNATIONAL FISHING AND RELATED... to Subpart E of Part 300—Prince William Sound Rural and Non-Rural Areas ER04NO09.010 [74 FR 57110...

Beyond Behaviour: Is Social Anxiety Low in Williams Syndrome?

Science.gov (United States)

Dodd, Helen F.; Schniering, Carolyn A.; Porter, Melanie A.

2009-01-01

Individuals with Williams syndrome (WS) exhibit striking social behaviour that may be indicative of abnormally low social anxiety. The present research aimed to determine whether social anxiety is unusually low in WS and to replicate previous findings of increased generalised anxiety in WS using both parent and self report. Fifteen individuals…

Biblionef SA: Bringing books to the bookless | Williams | Innovation

African Journals Online (AJOL)

Biblionef SA: Bringing books to the bookless. Jean Williams. Abstract. No abstract available. Innovation (2003) No. 26, pp 43-47. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians ...

William Knocke receives 2008 Virginia Outstanding Civil Engineer Award

OpenAIRE

Daniilidi, Christina

2008-01-01

William R. Knocke, W.C. English Professor and head of the Charles E. Via, Jr. Department of Civil and Environmental Engineering at Virginia Tech, was awarded the 2008 Virginia Outstanding Civil Engineer Award at the Virginia Section of the American Society of Civil Engineers' (ASCE) banquet, held recently in Williamsburg, Va.

Language and Literacy Development of Children with Williams Syndrome

Science.gov (United States)

Mervis, Carolyn B.

2009-01-01

Williams syndrome is a rare neurodevelopmental disorder caused by deletion of approximately 25 genes on chromosome 7q11.23. Children with the syndrome evidence large individual differences in both broad language and reading abilities. Nevertheless, as a group, children with this syndrome show a consistent pattern characterized by relative…

Musicality Correlates with Sociability and Emotionality in Williams Syndrome

Science.gov (United States)

Ng, Rowena; Lai, Philip; Levitin, Daniel J.; Bellugi, Ursula

2013-01-01

Williams syndrome (WS) is a neurogenetic developmental disorder characterized by peaks and valleys of cognitive abilities. One peak that has been understudied is the affinity that many individuals with WS have with music. It remains unknown whether their high levels of musical interest, skill, and expressivity are related to their sociable…

Pulmonary arterial stent implantation in an adult with Williams syndrome

NARCIS (Netherlands)

Reesink, Herre J.; Henneman, Onno D. F.; van Delden, Otto M.; Biervliet, Jules D.; Kloek, Jaap J.; Reekers, Jim A.; Bresser, Paul

2007-01-01

We report a 38-year-old patient who presented with pulmonary hypertension and right ventricular dysfunction due to pulmonary artery stenoses as a manifestation of Williams syndrome, mimicking chronic thromboembolic pulmonary hypertension. The patient was treated with balloon angioplasty and stent

77 FR 66087 - Federal Perkins Loan Program, Federal Family Education Loan Program, and William D. Ford Federal...

Science.gov (United States)

2012-11-01

..., and 685 Federal Perkins Loan Program, Federal Family Education Loan Program, and William D. Ford... 685 RIN 1840-AD05 [Docket ID ED-2012-OPE-0010] Federal Perkins Loan Program, Federal Family Education... (Perkins Loan) program, Federal Family Education Loan (FFEL) program, and William D. Ford Federal Direct...

Binding of Visual and Spatial Short-Term Memory in Williams Syndrome and Moderate Learning Disability

Science.gov (United States)

Jarrold, Christopher; Phillips, Caroline; Baddeley, Alan D

2007-01-01

A main aim of this study was to test the claim that individuals with Williams syndrome have selectively impaired memory for spatial as opposed to visual information. The performance of 16 individuals with Williams syndrome (six males, 10 females; mean age 18y 7mo [SD 7y 6mo], range 9y 1mo-30y 7mo) on tests of short-term memory for item and…

Samuel Alexander Kinnier Wilson. Wilson's disease, Queen Square and neurology.

Science.gov (United States)

Broussolle, E; Trocello, J-M; Woimant, F; Lachaux, A; Quinn, N

2013-12-01

This historical article describes the life and work of the British physician Samuel Alexander Kinnier Wilson (1878-1937), who was one of the world's greatest neurologists of the first half of the 20th century. Early in his career, Wilson spent one year in Paris in 1903 where he learned from Pierre-Marie at Bicêtre Hospital. He subsequently retained uninterrupted links with French neurology. He also visited in Leipzig the German anatomist Paul Flechsig. In 1904, Wilson returned to London, where he worked for the rest of his life at the National Hospital for the Paralysed and Epileptic (later the National Hospital for Nervous Diseases, and today the National Hospital for Neurology and Neurosurgery) in Queen Square, and also at Kings' College Hospital. He wrote on 'the old motor system and the new', on disorders of motility and muscle tone, on the epilepsies, on aphasia, apraxia, tics, and pathologic laughing and crying, and most importantly on Wilson's disease. The other objective of our paper is to commemorate the centenary of Wilson's most important work published in 1912 in Brain, and also in Revue Neurologique, on an illness newly recognized and characterized by him entitled "Progressive lenticular degeneration, a familial nervous disease associated with liver cirrhosis". He analyzed 12 clinical cases, four of whom he followed himself, but also four cases previously published by others and a further two that he considered in retrospect had the same disease as he was describing. The pathological profile combined necrotic damage in the lenticular nuclei of the brain and hepatic cirrhosis. This major original work is summarized and discussed in the present paper. Wilson not only delineated what was later called hepato-lenticular degeneration and Wilson's disease, but also introduced for the first time the terms extrapyramidal syndrome and extrapyramidal system, stressing the role of the basal ganglia in motility. The present historical work emphasizes the special

Prince William Sound, Alaska ESI: ESI (Environmental Sensitivity Index Shoreline Types)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set comprises the Environmental Sensitivity Index (ESI) data for Prince William Sound, Alaska. ESI data characterize estuarine environments and wildlife by...

Brief Report: Repetitive Behaviour Profiles in Williams Syndrome: Cross Syndrome Comparisons with Prader-Willi and Down Syndromes

Science.gov (United States)

Royston, R.; Oliver, C.; Moss, J.; Adams, D.; Berg, K.; Burbidge, C.; Howlin, P.; Nelson, L.; Stinton, C.; Waite, J.

2018-01-01

This study describes the profile of repetitive behaviour in individuals with Williams syndrome, utilising cross-syndrome comparisons with people with Prader-Willi and Down syndromes. The Repetitive Behaviour Questionnaire was administered to caregivers of adults with Williams (n = 96), Prader-Willi (n = 103) and Down (n = 78) syndromes. There were…

Astronaut William Fisher preparing to train in the WETF

Science.gov (United States)

1985-01-01

Astronaut William Fisher is shown in his extravehicular mobility unit (EMU) preparing to train in the Weightless Environment Training Facility (WETF). He is wearing the communications carrier assembly but not the full helmet (32102); Reflections of the WETF can be seen on the closed visor of the EMU helmet Fiser is wearing (32103).

Climatic data for Williams Lake, Hubbard County, Minnesota, 1983

Science.gov (United States)

Sturrock, A.M.; Rosenberry, D.O.; Engelbrecht, L.G.; Gothard, W.A.; Winter, T.C.

1984-01-01

Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies,including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar radiation. Data are collected at raft and land stations.

Generalized Bragg-Williams method for 'antiferromagnetic' lattice gases

International Nuclear Information System (INIS)

Osorio, R.

1983-01-01

The many-sublattice Bragg-Williams approximation of statistical mechanics is applied to the two-dimensional square and triangular lattice-gas models with nearest-neighbor repulsive interactions. Each problem is solved through both the canonical and grand-canonical methods. The present treatment emphasizes the duality between concentration and chemical potential and illustrates the appearance of first- and second -order transitions in each method. (Author) [pt

Binding of visual and spatial short-term memory in Williams syndrome and moderate learning disability.

Science.gov (United States)

Jarrold, Christopher; Phillips, Caroline; Baddeley, Alan D

2007-04-01

A main aim of this study was to test the claim that individuals with Williams syndrome have selectively impaired memory for spatial as opposed to visual information. The performance of 16 individuals with Williams syndrome (six males, 10 females; mean age 18y 7mo [SD 7y 6mo], range 9y 1mo-30y 7mo) on tests of short-term memory for item and location information was compared with that shown by individuals with moderate learning difficulties (12 males, four females; mean age 10y 3mo [SD 1y], range 8y 6mo-11y 7mo) and typically developing children (six males, 10 females; mean age 6y 8mo [SD 7mo], range 5y 10mo-7y 9mo) of an equivalent level of visuospatial ability. A second aim was to determine whether individuals had impaired ability to 'bind' visual spatial information when required to recall 'item in location' information. In contrast to previous findings, there was no evidence that individuals with Williams syndrome were more impaired in the spatial than the visual memory condition. However, individuals with both Williams syndrome and moderate learning difficulties showed impaired memory for item in location information, suggesting that problems of binding may be generally associated with learning disability.

Williams Syndrome: Daily Challenges and Positive Impact on the Family

Science.gov (United States)

Scallan, Susan; Senior, Joyce; Reilly, Colin

2011-01-01

Background: Despite the distinctive physical, cognitive, personality and behavioural characteristics associated with Williams syndrome, few studies to date have examined parental experiences of raising a child with this genetic syndrome. Methods: This explorative pilot study employed predominantly qualitative methodologies via face-to-face…

77 FR 76414 - William D. Ford Federal Direct Loan Program

Science.gov (United States)

2012-12-28

... Federal Direct Loan Program AGENCY: Department of Education. ACTION: Final regulations; correction... Loan (Perkins Loan) Program; the Federal Family Education Loan (FFEL) Program; and the William D. Ford Federal Direct Loan (Direct Loan) Program, including the Public Service Loan Forgiveness (PSLF) Program...

Williams' paradox and the role of phenotypic plasticity in sexual systems.

Science.gov (United States)

Leonard, Janet L

2013-10-01

As George Williams pointed out in 1975, although evolutionary explanations, based on selection acting on individuals, have been developed for the advantages of simultaneous hermaphroditism, sequential hermaphroditism and gonochorism, none of these evolutionary explanations adequately explains the current distribution of these sexual systems within the Metazoa (Williams' Paradox). As Williams further pointed out, the current distribution of sexual systems is explained largely by phylogeny. Since 1975, we have made a great deal of empirical and theoretical progress in understanding sexual systems. However, we still lack a theory that explains the current distribution of sexual systems in animals and we do not understand the evolutionary transitions between hermaphroditism and gonochorism. Empirical data, collected over the past 40 years, demonstrate that gender may have more phenotypic plasticity than was previously realized. We know that not only sequential hermaphrodites, but also simultaneous hermaphrodites have phenotypic plasticity that alters sex allocation in response to social and environmental conditions. A focus on phenotypic plasticity suggests that one sees a continuum in animals between genetically determined gonochorism on the one hand and simultaneous hermaphroditism on the other, with various types of sequential hermaphroditism and environmental sex determination as points along the spectrum. Here I suggest that perhaps the reason we have been unable to resolve Williams' Paradox is because the problem was not correctly framed. First, because, for example, simultaneous hermaphroditism provides reproductive assurance or dioecy ensures outcrossing does not mean that there are no other evolutionary paths that can provide adaptive responses to those selective pressures. Second, perhaps the question we need to ask is: What selective forces favor increased versus reduced phenotypic plasticity in gender expression? It is time to begin to look at the question

Infrared astronomy seeing the heat : from William Herschel to the Herschel space observatory

CERN Document Server

Clements, David L

2014-01-01

Uncover the Secrets of the Universe Hidden at Wavelengths beyond Our Optical GazeWilliam Herschel's discovery of infrared light in 1800 led to the development of astronomy at wavelengths other than the optical. Infrared Astronomy - Seeing the Heat: from William Herschel to the Herschel Space Observatory explores the work in astronomy that relies on observations in the infrared. Author David L. Clements, a distinguished academic and science fiction writer, delves into how the universe works, from the planets in our own Solar System to the universe as a whole. The book first presents the major t

Prof. Samuel ting presents results from AMS experiment at CERN main auditorium. Geneva 3 April 2013. The international team running the Alpha Magnetic Spectrometer (AMS1) today announced the first results in its search for dark matter

CERN Multimedia

Samuel Morier-Genoud

2013-01-01

Geneva 3 April 2013. The international team running the Alpha Magnetic Spectrometer (AMS) today announced the first results in its search for dark matter. The results, presented by AMS spokesperson Professor Samuel Ting in a seminar at CERN, are to be published in the journal Physical Review Letters. They report the observation of an excess of positrons in the cosmic ray flux

The Role of Spiral Multidetector Dynamic CT in the Study of Williams-Campbell Syndrome

International Nuclear Information System (INIS)

Scioscio, V. di; Zompatori, M.; Mistura, I.; Montanari, P.; Santilli, L.; Luccaroni, R.; Sverzellati, N.

2006-01-01

Williams-Campbell syndrome is a cystic bronchiectatic disease secondary to deficiency or defect of cartilaginous plates in the wall of the airways. In the literature, two main forms are suggested: congenital and acquired (post-infectious). The most frequent symptoms are represented by recurrent pulmonary infections from childhood. Multislice spiral dynamic CT has a major role in the study of cystic pulmonary disease and in differentiating Williams-Campbell syndrome from the other causes of cystic bronchiectasis, in which even lung function tests can give deceptive results

The Role of Spiral Multidetector Dynamic CT in the Study of Williams-Campbell Syndrome

Energy Technology Data Exchange (ETDEWEB)

Scioscio, V. di; Zompatori, M.; Mistura, I.; Montanari, P.; Santilli, L.; Luccaroni, R.; Sverzellati, N. [Medical Univ. of Bologna, S. Orsola-Malpighi Policlinic (Italy). Dept. of Radiology

2006-10-15

Williams-Campbell syndrome is a cystic bronchiectatic disease secondary to deficiency or defect of cartilaginous plates in the wall of the airways. In the literature, two main forms are suggested: congenital and acquired (post-infectious). The most frequent symptoms are represented by recurrent pulmonary infections from childhood. Multislice spiral dynamic CT has a major role in the study of cystic pulmonary disease and in differentiating Williams-Campbell syndrome from the other causes of cystic bronchiectasis, in which even lung function tests can give deceptive results.

A Starry Diamond in a Veil of Light: Artistic and Literary Suggestions of a Comet

Science.gov (United States)

Gasperini, A.; Galli, D.

2016-01-01

Donati's Comet, discovered in Florence on June 2, 1858, was one of the most spectacular astronomical events of the nineteenth century. It could be seen with the naked eye during September and October 1858, when it reached its highest splendour. The sight of the comet, with its bright nucleus and its long, curved tail, inspired paintings, watercolors, engravings, and sketches by artists such as William Dyce, Samuel Palmer, and William Turner of Oxford. Donati's Comet is mentioned in the works of several contemporary writers and poets (Hawthorne, Dickens, Hardy, and Verne), and in the diaries of explorers and travelers all around the world. Long-lasting traces of the impression left by Donati's Comet are found in many forms of popular art and literature (ladies' magazines, children's books, collection cards, and advertisements) until the beginning of the twentieth century. This paper focuses on a few examples of this fascination, emphasizing the connections among the astronomical event and the artistic sensibility of the period.

Notes of John Smith as a Source for the Crimean Khanate History in the early 17th century »

Directory of Open Access Journals (Sweden)

N.I. Khrapunov

2015-12-01

Full Text Available The paper analyses the account of Tataria collected by famous English adventurer John Smith. In 1602, Smith, a mercenary in Transylvania, was captivated by pillagers and, later, sold into slavery. In spring of 1603 he found himself a slave somewhere in the Azov Sea Area, in the land of the Crimean Khanate. A few months later, Smith succeeded to escape, he reached the Moscow czar’s country, and whence returned to Transylvania. Twenty years after, Smith published his life story in short (1625 and then long version (1630. A considerable part of the story was the account of the author’s adventures among the Turks and the Tatars. Smith widely used other travellers’ accounts (William Biddulph, Antony Jenkinson, William of Rubruck, and Martin Broniovius, collected by famous Samuel Purchas, the first publisher of Smith’s own story. Now we can determine original materials by Smith, based on his personal experience, which describe the Crimean Khanate’s daily life and warfare.

Climatic data for Williams Lake, Hubbard County, Minnesota, 1985

Science.gov (United States)

Sturrock, A.M.; Rosenberry, D.O.; Winter, T.C.

1987-01-01

Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies, including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Data are collected at raft and land stations.

Climatic data for Williams Lake, Hubbard County, Minnesota, 1984

Science.gov (United States)

Sturrock, A.M.; Rosenberry, D.O.; Scarborough, J.L.; Winter, T.C.

1986-01-01

Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies, including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Data are collected at raft and land stations.

Random Thoughts on William Shakespeare and Medicine

OpenAIRE

KV Sahasranam

2017-01-01

Medicine and literature have always been connected over the ages. William Shakespeare (1564-1616) is no exception. There are plenty of references to medicine and diseases in the works of Shakespeare. The knowledge which Shakespeare has of medical conditions is much more than is expected of a common man. This is attributed to his association with practitioners of his time and reading of contemporary texts in medicine. Also his son in law Dr. John Hall who married Susanna, Shakespeare's eldest ...

Mapping cultural resource sites for the Prince William Sound Graphical Resource Database

International Nuclear Information System (INIS)

Wooley, C. B.; O'Brien, D. K.; Hillman, S. O.

1997-01-01

A software package for mapping digital data 'layers' of environmentally and/or culturally sensitive areas such as seabird colonies, seal haulouts, and sea otter concentrations in Prince William Sound and adjoining areas of southern Alaska has been developed by the Alyeska Pipeline Service Company. The data is to be added to an environmental computer mapping database. More than 1,800 known and reported coastal cultural resource sites have been identified. The database is part of the Prince William Sound Tanker Oil Discharge Prevention and Contingency Plan. The mappable data layers can be used to plan and execute whatever site protection program may be necessary, thus enhancing effective cultural resource protection during an oil spill response. 22 refs., 4 figs

77 FR 32625 - William J. Stevenson, Estate of Lynn E. Stevenson, Black Canyon Bliss, LLC; Notice of Application...

Science.gov (United States)

2012-06-01

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 8866-010] William J. Stevenson, Estate of Lynn E. Stevenson, Black Canyon Bliss, LLC; Notice of Application for Transfer of License, and Soliciting Comments and Motions To Intervene On April 23, 2012, William J. Stevenson, Estate...

78 FR 33395 - Annual Updates to the Income Contingent Repayment (ICR) Plan Formula for 2013-William D. Ford...

Science.gov (United States)

2013-06-04

... DEPARTMENT OF EDUCATION Annual Updates to the Income Contingent Repayment (ICR) Plan Formula for 2013--William D. Ford Federal Direct Loan Program Catalog of Federal Domestic Assistance (CFDA) Number... free, at 1- 800-877-8339. SUPPLEMENTARY INFORMATION: Under the William D. Ford Federal Direct Loan...

The importance of strategic leadership in strategy implementation in a chemical industry / by Magauta M.J.S. Mosia

OpenAIRE

Mosia, Matinyane Magauta Justina Suzanne

2003-01-01

The global economy is a major irrevocable event whose existence has already had a major influence on organisations today and has created a new competitive landscape in which events change constantly and unpredictably (Ireland & Hitt, 1999). The creation of sustainable competitive advantage is the universal objective of all companies (Campbell & Alexander, 1998). Ireland and Hitt (1999) believe that being able to exercise strategic leadership in a competitively superior manner will facilitate ...

77 FR 72960 - William D. Ford Federal Direct Loan Program

Science.gov (United States)

2012-12-07

... Federal Direct Loan Program AGENCY: Office of Postsecondary Education, Department of Education. ACTION... document to establish the date for the early implementation of William D. Ford Federal Direct Loan (Direct Loan) program regulations that establish a new income-contingent repayment plan based on the President...

Case report of sudden death in a child with Williams syndrome ...

African Journals Online (AJOL)

A two year old child, confirmed with Williams syndrome (WS) ... and no relevant cardiac history such as chest pain or episodes ... brain, abdominal and pelvic organ blocks. .... a fully functional operating theatre complex presents a number.

WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

Energy Technology Data Exchange (ETDEWEB)

NONE

2015-06-15

Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

WE-G-213-00: History Symposium: Radiological Physics Pioneers: Roentgen and the AAPM Award Eponyms - William Coolidge, Edith Quimby, and Marvin Williams - Who Were They and What Did They Do?

International Nuclear Information System (INIS)

2015-01-01

Roentgen and the Birth of Modern Medical Physics – Perry Sprawls Wilhelm Roentgen is well known for his discovery of x-radiation. What is less known and appreciated is his intensive research following the discovery to determine the characteristics of the “new kind of radiation” and demonstrate its great value for medical purposes. In this presentation we will imagine ourselves in Roentgen’s mind and follow his thinking, including questions and doubts, as he designs and conducts a series of innovative experiments that provided the foundation for the rapid growth of medical physics. Learning Objectives: Become familiar with the personal characteristics and work of Prof. Roentgen that establishes him as an inspiring model for the medical physics profession. Observe the thought process and experiments that determined and demonstrated the comprehensive characteristics of x-radiation. The AAPM Award Eponyms: William D. Coolidge, Edith H. Quimby, and Marvin M.D. Williams - Who were they and what did they do? – Lawrence N. Rothenberg William David Coolidge (1873–1975) William Coolidge was born in Hudson, NY in 1873. He obtained his BS at the Massacusetts Institute of Technology in 1896. Coolidge then went to the University of Leipzig, Germany for graduate study with physicists Paul Drude and Gustave Wiedemann and received a Ph.D. in 1899. While in Germany he met Wilhelm Roentgen. Coolidge returned to the US to teach at MIT where he was associated with Arthur A. Noyes of the Chemistry Department, working on the electrical conductivity of aqueous solutions. Willis R. Whitney, under whom Coolidge had worked before going to Germany, became head of the newly formed General Electric Research Laboratory and he invited Coolidge to work with him. In 1905, Coolidge joined the staff of the GE laboratory and was associated with it for the remainder of his life. He developed ductile tungsten filaments to replace fragile carbon filaments as the material for electric light

WEAVE: the next generation wide-field spectroscopy facility for the William Herschel Telescope : The next generation wide-field spectroscopy facility for the William Herschel Telescope

NARCIS (Netherlands)

Dalton, Gavin; Trager, Scott C.; Abrams, Don Carlos; Carter, David; Bonifacio, Piercarlo; Aguerri, J. Alfonso L.; MacIntosh, Mike; Evans, Chris; Lewis, Ian; Navarro, Ramon; Agocs, Tibor; Dee, Kevin; Rousset, Sophie; Tosh, Ian; Middleton, Kevin; Pragt, Johannes; Terrett, David; Brock, Matthew; Benn, Chris; Verheijen, Marc; Cano Infantes, Diego; Bevil, Craige; Steele, Iain; Mottram, Chris; Bates, Stuart; Gribbin, Francis J.; Rey, Jürg; Rodriguez, Luis Fernando; Delgado, Jose Miguel; Guinouard, Isabelle; Walton, Nic; Irwin, Michael J.; Jagourel, Pascal; Stuik, Remko; Gerlofsma, Gerrit; Roelfsma, Ronald; Skillen, Ian; Ridings, Andy; Balcells, Marc; Daban, Jean-Baptiste; Gouvret, Carole; Venema, Lars; Girard, Paul

We present the preliminary design of the WEAVE next generation spectroscopy facility for the William Herschel Telescope (WHT), principally targeting optical ground-based follow up of upcoming ground-based (LOFAR) and spacebased (Gaia) surveys. WEAVE is a multi-object and multi-IFU facility utilizing

Arterial Hypertension in a Child with Williams-Beuren Syndrome (7q11.23 Chromosomal Deletion

Directory of Open Access Journals (Sweden)

Cristina de Sylos

2002-08-01

Full Text Available We report the case of a 7-year-old male child diagnosed with Williams-Beuren syndrome and arterial hypertension refractory to clinical treatment. The diagnosis was confirmed by genetic study. Narrowing of the descending aorta and stenosis of the renal arteries were also diagnosed. Systemic vascular alterations caused by deletion of the elastin gene may occur early in individuals with Williams-Beuren syndrome, leading to the clinical manifestation of systemic arterial hypertension refractory to drug treatment.

Relationship of the Williams-Poulios and Manning-Rosen Potential Energy Models for Diatomic Molecules

Science.gov (United States)

Jia, Chun-Sheng; Liang, Guang-Chuan; Peng, Xiao-Long; Tang, Hong-Ming; Zhang, Lie-Hui

2014-06-01

By employing the dissociation energy and the equilibrium bond length for a diatomic molecule as explicit parameters, we generate an improved form of the Williams-Poulios potential energy model. It is found that the negative Williams-Poulios potential model is equivalent to the Manning-Rosen potential model for diatomic molecules. We observe that the Manning-Rosen potential is superior to the Morse potential in reproducing the interaction potential energy curves for the {{a}3 Σu+} state of the 6Li2 molecule and the {{X}1 sum+} state of the SiF+ molecule.

Atypical Sleep Architecture and Altered EEG Spectra in Williams Syndrome

Science.gov (United States)

Gombos, F.; Bodizs, R.; Kovacs, I.

2011-01-01

Background: Williams syndrome (WS) is a neurodevelopmental genetic disorder characterised by physical abnormalities and a distinctive cognitive profile with intellectual disabilities (IDs) and learning difficulties. Methods: In our study, nine adolescents and young adults with WS and 9 age- and sex-matched typically developing (TD) participants…

Comparison of the acute effects of Tulbaghia violacea William Henry ...

African Journals Online (AJOL)

Purpose: To assess the effect of the crude methanol leaf extracts of Tulbaghia violacea William Henry Harvey (Alliaceae) on blood pressure (BP) and heart rate in ageing normotensive Wistar Kyoto rats (WKY), and compare the results obtained with those for adult spontaneously hypertensive rats (SHR). Methods: T.

Dual-Task Processing as a Measure of Executive Function: A Comparison between Adults with Williams and Down Syndromes

Science.gov (United States)

Kittler, Phyllis M.; Krinsky-McHale, Sharon J.; Devenny, Darlynne A.

2008-01-01

Behavioral phenotypes of individuals with Williams syndrome and individuals with Down syndrome have been contrasted in relation to short-term memory. People with Down syndrome are stronger visuospatially and those with Williams syndrome are stronger verbally. We examined short-term memory, then explored whether dual-task processing further…

77 FR 30266 - Annual Updates to the Income Contingent Repayment (ICR) Plan Formula for 2012; William D. Ford...

Science.gov (United States)

2012-05-22

... DEPARTMENT OF EDUCATION Annual Updates to the Income Contingent Repayment (ICR) Plan Formula for 2012; William D. Ford Federal Direct Loan Program AGENCY: Federal Student Aid, Department of Education... announces the annual updates to the ICR plan formula for 2012. Under the William D. Ford Federal Direct Loan...

77 FR 20796 - Annual Updates to the Income Contingent Repayment (ICR) Plan Formula for 2011; William D. Ford...

Science.gov (United States)

2012-04-06

... DEPARTMENT OF EDUCATION Annual Updates to the Income Contingent Repayment (ICR) Plan Formula for 2011; William D. Ford Federal Direct Loan Program AGENCY: Federal Student Aid, Department of Education... announces the annual updates to the ICR plan formula for 2011. Under the William D. Ford Federal Direct Loan...

A child of Williams-Beuren syndrome for inguinal hernia repair: Perioperative management concerns

Directory of Open Access Journals (Sweden)

Sangeeta Deka

2016-01-01

Full Text Available Williams-Beuren syndrome, commonly known as Williams syndrome (WS, is a multi-organ disorder. The principal anomalies of the syndrome are developmental delay, unusual craniofacial dysmorphic features, and cardiovascular anomalies such as valvular or supravalvular aortic stenosis, pulmonary artery stenosis, and coronary insufficiency. Sudden cardiac death during minor procedures even in the absence of gross cardiovascular pathology is the most dreaded complication in these patients. A 7-year-old child with WS was posted for left-sided inguinal hernia repair under general anesthesia. Our article describes the uneventful perioperative course of the patient and highlights the concerns and complications that may be an integral part with the syndrome.

William Henry Bragg, man and scientist, Nobel Laureate and First Professor of Physics, University of Adelaide 1886-1909.

Science.gov (United States)

Patterson, John; George, Robert

2018-03-01

In London, November 1915, a telegram was received at the home of William Henry Bragg from the secretary of the Academy of Science in Stockholm announcing the award of the Nobel Prize in Physics for "the analysis of crystal structures by means of X-rays". A second similar telegram was addressed to his 25 year old son William Lawrence Bragg (Jenkin, 2008). This article commemorates the centenary of that event and the unveiling of a bust of Sir William Bragg alongside that of his son, Sir Lawrence Bragg, on North Terrace in Adelaide where he spent 23 years of his early career. Copyright © 2018. Published by Elsevier Ltd.

The Interplay between Anxiety and Social Functioning in Williams Syndrome

Science.gov (United States)

Riby, Deborah M.; Hanley, Mary; Kirk, Hannah; Clark, Fiona; Little, Katie; Fleck, Ruth; Janes, Emily; Kelso, Linzi; O'Kane, Fionnuala; Cole-Fletcher, Rachel; Allday, Marianne Hvistendahl; Hocking, Darren; Cornish, Kim; Rodgers, Jacqui

2014-01-01

The developmental disorder Williams syndrome (WS) has been associated with an atypical social profile of hyper-sociability and heightened social sensitivity across the developmental spectrum. In addition, previous research suggests that both children and adults with WS have a predisposition towards anxiety. The current research aimed to explore…

Ronald William Hodges, 1934-2017: Eminent Lepidopterist and Great Mentor

Science.gov (United States)

Dr. Ronald William Hodges (1934-2017) was an eminent lepidopterist and former Research Leader of the Systematic Entomology Laboratory from 1976 to 1979. He published on 117 genera (21 new), 806 species (351 new), 36 subfamilies (7 new), and 16 families (7 new) about gelechioid micromoths. He was awa...

Inversion of the Williams syndrome region is a common polymorphism found more frequently in parents of children with Williams syndrome.

Science.gov (United States)

Hobart, Holly H; Morris, Colleen A; Mervis, Carolyn B; Pani, Ariel M; Kistler, Doris J; Rios, Cecilia M; Kimberley, Kendra W; Gregg, Ronald G; Bray-Ward, Patricia

2010-05-15

Williams syndrome (WS) is a multisystem disorder caused by deletion of about 1.55 Mb of DNA (including 26 genes) on chromosome 7q11.23, a region predisposed to recombination due to its genomic structure. Deletion of the Williams syndrome chromosome region (WSCR) occurs sporadically. To better define chance for familial recurrence and to investigate the prevalence of genomic rearrangements of the region, 257 children with WS and their parents were studied. We determined deletion size in probands by metaphase FISH, parent-of-origin of the deleted chromosome by molecular genetic methods, and inversion status of the WSCR in both parents by interphase FISH. The frequency of WSCR inversion in the transmitting parent group was 24.9%. In contrast, the rate of inversion in the non-transmitting parent group (a reasonable estimate of the rate in the general population) was 5.8%. There were no significant gender differences with respect to parent-of-origin for the deleted chromosome or the incidence of the inversion polymorphism. There was no difference in the rate of spontaneous abortion for mothers heterozygous for the WSCR inversion relative to mothers without the inversion. We calculate that for a parent heterozygous for a WSCR inversion, the chance to have a child with WS is about 1 in 1,750, in contrast to the 1 in 9,500 chance for a parent without an inversion.

Perceptual Speech and Paralinguistic Skills of Adolescents with Williams Syndrome

Science.gov (United States)

Hargrove, Patricia M.; Pittelko, Stephen; Fillingane, Evan; Rustman, Emily; Lund, Bonnie

2013-01-01

The purpose of this research was to compare selected speech and paralinguistic skills of speakers with Williams syndrome (WS) and typically developing peers and to demonstrate the feasibility of providing preexisting databases to students to facilitate graduate research. In a series of three studies, conversational samples of 12 adolescents with…

Comprehension of Metaphor and Metonymy in Children with Williams Syndrome

Science.gov (United States)

Annaz, Dagmara; Van Herwegen, Jo; Thomas, Michael; Fishman, Roza; Karmiloff-Smith, Annette; Rundblad, Gabriella

2009-01-01

Background: Figurative language, such as metaphor and metonymy, is very common in daily language use. Its underlying cognitive processes are sometimes viewed as lying at the interface of language and thought. Williams syndrome, which is a rare genetic developmental disorder, provides an opportunity to study this interface because individuals with…

The West Family Chiropractic Dynasty: celebrating a century of accomplishment in Canada: Part I: Archibald B. West, DC, Samuel H. West, DC and Stephen E. West, DC: The Founding Father, his Son and Grandson.

Science.gov (United States)

Brown, Douglas M

2010-09-01

This historical treatise documents the unbroken legacy of the West family of chiropractors which has flourished in Canada for over 100 years. Part I, unearths the origins, development and careers of Archibald West, the founder of this dynasty, his son Samuel and grandson Stephen. Part II, not yet ready for publication, will delve into the lives of Archibald's brother Samson and his chiropractic progeny, as well as a nephew of Stephen and another relative of Frederick West.

How Flexible is the Use of Egocentric Versus Allocentric Frame of Reference in the Williams Syndrome Population?

Science.gov (United States)

Heiz, J; Majerus, S; Barisnikov, K

2017-09-28

This study examined the spontaneous use of allocentric and egocentric frames of reference and their flexible use as a function of instructions. The computerized spatial reference task created by Heiz and Barisnikov (2015) was used. Participants had to choose a frame of reference according to three types of instructions: spontaneous, allocentric and egocentric. The performances of 16 Williams Syndrome participants between 10 and 41 years were compared to those of two control groups (chronological age and non-verbal intellectual ability). The majority of Williams Syndrome participants did not show a preference for a particular frame of reference. When explicitly inviting participants to use an allocentric frame of reference, all three groups showed an increased use of the allocentric frame of reference. At the same time, an important heterogeneity of type of frame of reference used by Williams Syndrome participants was observed. Results demonstrate that despite difficulties in the spontaneous use of allocentric and egocentric frames of reference, some Williams Syndrome participants show flexibility in the use of an allocentric frame of reference when an explicit instruction is provided. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

La haine à l’œuvre dans Carpenter’s Gothic (1999 de William Gaddis Cultivating Hatred in Carpenter’s Gothic (1999 by William Gaddis

Directory of Open Access Journals (Sweden)

Jacques Sohier

2007-01-01

Full Text Available In Carpenter’s Gothic, hatred is given pride of place. William Gaddis delineates a society in which hatred proliferates. Characters are caught in the turmoils of their hatred whether it derives from the Vietnam War or from fundamentalist movements, from their individualistic quest for social recognition or from self-aggrandizement. We mean to develop a typology derived from psychoanalysis and anthropology so as to take into account all the different facets hate has in the novel. We shall devote analyses to jealousy caused by hatred, then describe the primary hate that underpins all types of relationships as a preliminary to questioning the excess that fuels Gaddis’s writing. Lastly, by referring to the author’s non-fictional work we shall put forward the thesis that the voluble protagonist is to a large extent the author’s mouthpiece. McCandless’s vindictive disquisitions on the course of the world will be seen as the equivalent of a tragic mask through which William Gaddis gives vent to his melancholia and intense detestation of the ways of the world.

William Butcher, Jules Verne inédit, les manuscrits déchiffrés

OpenAIRE

Merello, Ida

2016-01-01

Les textes de Jules Verne sont des palimpsestes. Ils le sont au sens figuré, nous le savions déjà. Mais ils le sont également au sens propre, comme le montre le bel ouvrage de William Butcher. Ce dernier s’est donné pour objectif d’analyser les manuscrits de Verne parvenus jusqu’à nous. La ressource semble inépuisable : des milliers et des milliers de pages autographes à déchiffrer, à défricher. William Butcher s’est plongé dans ce labeur avec enthousiasme et il en tire de nombreuses informat...

George Fulford and Victorian patent medicine men: Quack mercenaries or Smilesian entrepreneurs?

Science.gov (United States)

Loeb, L

1999-01-01

In the early twentieth century, a time when patent medicine men were stereotyped as evil and dishonest, G. T. Fulford of Brockville, Ontario made his fortune from an iron pill called Dr. Williams' Pink Pills for Pale People. Once successful, Fulford remained in Brockville where he served on the town council and gave generously to charities. In 1900 he was appointed by Laurier to the Senate. When he died in 1905 he was remembered as a kind and ethical man. His story, like that of several other prominent patent medicine men, conforms more with the ideals of Samuel Smiles than with the popular image of disrepute.

David Cronenberg ja William S. Burroughs kutsuvad teid lantshile / Aare Ermel

Index Scriptorium Estoniae

Ermel, Aare, 1957-2013

1999-01-01

Mängufilm "Alasti eine" ("Naked Lunch") William S. Burroughs' teose järgi : režissöör ja stsenarist David Cronenberg : Suurbritannia - Kanada 1991. Lähemalt režissööri kohta. Ka Nädal nr. 35, lk. 29

Examining Reports of Mental Health in Adults with Williams Syndrome

Science.gov (United States)

Stinton, Chris; Tomlinson, Katie; Estes, Zachary

2012-01-01

Prior research suggests that individuals with Williams syndrome (WS) have a disposition towards anxiety. Information regarding this is typically derived from parents and carers. The perspectives of the individuals with WS are rarely included in research of this nature. We examined the mental health of 19 adults with WS using explicit (psychiatric…

Human versus Non-Human Face Processing: Evidence from Williams Syndrome

Science.gov (United States)

Santos, Andreia; Rosset, Delphine; Deruelle, Christine

2009-01-01

Increased motivation towards social stimuli in Williams syndrome (WS) led us to hypothesize that a face's human status would have greater impact than face's orientation on WS' face processing abilities. Twenty-nine individuals with WS were asked to categorize facial emotion expressions in real, human cartoon and non-human cartoon faces presented…

Personal Space Regulation in Williams Syndrome: The Effect of Familiarity

Science.gov (United States)

Lough, Emma; Flynn, Emma; Riby, Deborah M.

2016-01-01

Personal space refers to a protective barrier that we strive to maintain around our body. We examined personal space regulation in young people with Williams syndrome (WS) and their typically developing, chronological age-matched peers using a parent report questionnaire and a stop-distance paradigm. Individuals with WS were reported by their…

William Gaddis’s Immortality: Celebration, Cartoon, or Corruption?

OpenAIRE

Alberts, Crystal

2013-01-01

Although ostensibly a review of 'The Letters of William Gaddis' edited by Steven Moore (Champaign: Dalkey Archive, 2013), this article evaluates Moore’s volume in light of generally accepted practices of scholarly editions and the handling of historical documents. In particular, Alberts compares some of Moore’s edited letters to the originals housed either at Washington University in St. Louis or the Harry Ransom Center at the University of Texas, Austin and reveals issues involving the repre...

Long-term memory for verbal and visual information in Down syndrome and Williams syndrome: performance on the Doors and People test.

Science.gov (United States)

Jarrold, Christopher; Baddeley, Alan D; Phillips, Caroline

2007-02-01

Previous studies have suggested that Williams syndrome and Down syndrome may be associated with specific short-term memory deficits. Individuals with Williams syndrome perform relatively poorly on tests of visuo-spatial short-term memory and individuals with Down syndrome show a relative deficit on verbal short-term memory tasks. However, these patterns of impairments may reflect the impact of generally impaired visuo-spatial processing skills in Williams syndrome, and verbal abilities in Down syndrome. The current study explored this possibility by assessing long-term memory among 15 individuals with Williams syndrome and 20 individuals with Down syndrome using the Doors and People test, a battery which assesses recall and recognition of verbal and visual information. Individuals' performance was standardised for age and level of intellectual ability with reference to that shown by a sample of 110 typically developing children. The results showed that individuals with Down syndrome have no differential deficits in long-term memory for verbal information, implying that verbal short-term memory deficits in this population are relatively selective. Instead both individuals with Down syndrome and with Williams syndrome showed some evidence of relatively poor performance on tests of long-term memory for visual information. It is therefore possible that visuo-spatial short-term memory deficits that have previously been demonstrated in Williams syndrome may be secondary to more general problems in visuo-spatial processing in this population.

Behavioral Profiles of Children with Williams Syndrome from Spain and the United States: Cross-Cultural Similarities and Differences

Science.gov (United States)

Pérez-García, Débora; Brun-Gasca, Carme; Pérez-Jurado, Luis A.; Mervis, Carolyn B.

2017-01-01

To identify similarities and differences in the behavioral profile of children with Williams syndrome from Spain (n = 53) and the United States (n = 145), we asked parents of 6- to 14-year-olds with Williams syndrome to complete the Child Behavior Checklist 6-18. The distribution of raw scores was significantly higher for the Spanish sample than…

William H. Sheldon and the culture of the somatotype

OpenAIRE

Gatlin, Stephen H.

1997-01-01

The burden of this dissertation is to show that William Sheldon's somatotype project should be seen as an integral aspect of modernist culture. Sheldon engaged the same problems with modernity and the "Second Industrial Revolution" (urbanization, overpopulation, industrialization, alienation) that confronted modernist poets, novelists, and philosophers. In this I am elaborating Dorothy Ross's recent metaphor, "modernist impulses in the human sciences" (1994). Both scientists and artists were ...

Unravelling starlight: William and Margaret Huggins and the rise of the new astronomy

National Research Council Canada - National Science Library

Becker, Barbara J

2011-01-01

...). A pioneer in adapting the spectroscope to new astronomical purposes, William Huggins rose to scientific prominence in London and transformed professional astronomy to become a principal founder...

How Executive Functions Are Related to Intelligence in Williams Syndrome

Science.gov (United States)

Osorio, Ana; Cruz, Raquel; Sampaio, Adriana; Garayzabal, Elena; Martinez-Regueiro, Rocio; Goncalves, Oscar F.; Carracedo, Angel; Fernandez-Prieto, Montse

2012-01-01

Williams syndrome is characterized by impairments in executive functions (EFs). However, it remains unknown how distinct types of EFs relate to intelligence in this syndrome. The present study analyzed performance on working memory, inhibiting and shifting, and its links to IQ in a sample of 17 individuals with WS, and compared them with a group…

Anterior segment dysgenesis associated with Williams-Beuren syndrome: a case report and review of the literature.

Science.gov (United States)

Todorova, Margarita G; Grieshaber, Matthias C; Cámara, Rafael J A; Miny, Peter; Palmowski-Wolfe, Anja M

2014-05-21

Williams-Beuren syndrome is characterized by mild mental retardation, specific neurocognitive profile, hypercalcemia during infancy, distinctive facial features and cardiovascular diseases. We report on complete ophthalmologic, sonographic and genetic evaluation of a girl with a clinical phenotype of Williams-Beuren syndrome, associated with unilateral anterior segment dysgenesis and bilateral cleft of the soft and hard palate. These phenotypic features have not been linked to the haploinsufficiency of genes involved in the microdeletion. A term born girl presented at the initial examination with clouding of the right cornea. On ultrasound biomicroscopy the anterior chamber structures were difficult to differentiate, showing severe adhesions from the opacified cornea to the iris with a kerato-irido-lenticular contact to the remnant lens, a finding consistent with Peters' anomaly. Genetic analyses including FISH confirmed a loss of the critical region 7q11.23, usually associated with the typical Williams-Beuren syndrome. Microsatellite analysis showed a loss of about 2.36 Mb. A diagnosis of Williams-Beuren syndrome was made based on the microdeletion of 7q11.23. The unique features, including unilateral microphthalmia and anterior segment dysgenesis, were unlikely to be caused by the microdeletion. Arguments in favor of the latter are unilateral manifestation, as well as the fact that numerous patients with deletions of comparable or microscopically visible size have not shown similar manifestations.

Categories are alive: interview with Brackette F. Williams

OpenAIRE

Durão, Susana; Bastos, Cristiana; Williams, Brackette F.

2013-01-01

Brackette F. Williams is an American anthropologist and a Senior Justice ­Advocate, currently an associate professor of Cultural Anthropology at the University of ­Arizona. She studied at the University of Cornell, the University of Arizona, and received her doctorate from Johns Hopkins University. Her work interweaves ­matters of race, gender, class, ideology and politics in a unique manner – as seen in the article “A class act: Anthropology and the race to nation across ethnic terrain” (Ann...

Fissured and geographic tongue in Williams-Beuren syndrome

Directory of Open Access Journals (Sweden)

Neeta Sharma

2014-01-01

Full Text Available Williams-Beuren Syndrome (WBS is a rare, most often sporadic, genetic disease caused by a chromosomal microdeletion at locus 7q11.23 involving 28 genes. It is characterized by congenital heart defects, neonatal hypercalcemia, skeletal and renal abnormalities, cognitive disorder, social personality disorder, and dysmorphic facies. A number of clinical findings has been reported, but none of the studies evaluated this syndrome considering oral cavity. We here report a fissured and geographic tongue in association with WBS.

The Interplay between Executive Control and Motor Functioning in Williams Syndrome

Science.gov (United States)

Hocking, Darren R.; Thomas, Daniel; Menant, Jasmine C.; Porter, Melanie A.; Smith, Stuart; Lord, Stephen R.; Cornish, Kim M.

2013-01-01

Previous studies suggest that individuals with Williams syndrome (WS), a rare genetically based neurodevelopmental disorder, show specific weaknesses in visual attention and response inhibition within the visuospatial domain. Here we examine the extent to which impairments in attentional control extend to the visuomotor domain using a…

Adaptive Behavior and Problem Behavior in Young Children with Williams Syndrome

Science.gov (United States)

Hahn, Laura J.; Fidler, Deborah J.; Hepburn, Susan L.

2014-01-01

The present study compares the adaptive behavior profile of 18 young children with Williams syndrome (WS) and a developmentally matched group of 19 children with developmental disabilities and examines the relationship between adaptive behavior and problem behaviors in WS. Parents completed the Vineland Adaptive Behavioral Scales--Interview…

40 CFR Appendix B to Part 425 - Modified Monier-Williams Method

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Modified Monier-Williams Method B Appendix B to Part 425 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) EFFLUENT GUIDELINES AND STANDARDS LEATHER TANNING AND FINISHING POINT SOURCE CATEGORY Pt. 425, App. B Appendix B to...

I Know! It's Backwards Day! Gender Roles and William's Doll

Science.gov (United States)

Van de Kleut, Geraldine

2007-01-01

This article presents a case study of an exploration of gender roles in a second-grade classroom. The author discusses some of the discursive identities in which she and her students are positioned, and then uses the picture book William's Doll to introduce a discussion of discursive gender identities with her students. She then asks students to…

Elicited Production of Relative Clauses in Children with Williams Syndrome

Science.gov (United States)

Zukowski, Andrea

2009-01-01

Relative clauses have been implicated alternately as a strength and a weakness in the language of people with Williams Syndrome (WS). To clarify the facts, an elicited production test was administered to 10 people with WS (age 10-16 years), 10 typically developing children (age 4-7 years), and 12 typically developing adults. Nearly every WS…

TENNESSEE WILLIAMS E O TEATRO MARGINAL GAY

Directory of Open Access Journals (Sweden)

Adriana Falqueto Lemos

2014-06-01

Full Text Available The work developed in this text aims to read the dramatist Tennnessee Williams in a play in two scenes “E Contar Tristes Histórias das Mortes das Bonecas” which was published in Brazil in the book “Mister Paradise e outras peças em um ato” (2011. The intention is to reflect upon one of his recurring themes, the marginalization. In order to perform the analysis, the theoretical support was grounded in “Literatura e Sociedade” by Antonio Candido (2006, concerning the participation of society and authorship in a piece of literature.

TENNESSEE WILLIAMS E O TEATRO MARGINAL GAY

Directory of Open Access Journals (Sweden)

Adriana Falqueto Lemos

2014-09-01

Full Text Available The work developed in this text aims to read the dramatist Tennnessee Williams in a play in two scenes “E Contar Tristes Histórias das Mortes das Bonecas” which was published in Brazil in the book “Mister Paradise e outras peças em um ato” (2011. The intention is to reflect upon one of his recurring themes, the marginalization. In order to perform the analysis, the theoretical support was grounded in “Literatura e Sociedade” by Antonio Candido (2006, concerning the participation of society and authorship in a piece of literature.

Samuel Holden Parsons Lee (1772-1863): American physician, entrepreneur and selfless fighter of the 1798 Yellow Fever epidemic of New London, Connecticut.

Science.gov (United States)

Mattie, James K; Desai, Sukumar P

2015-02-01

Samuel Holden Parsons Lee practised medicine at a time when the germ theory of disease had not yet been proposed and antibiotics remained undiscovered. In 1798 he served selflessly as the only physician in town who was willing to battle the Yellow Fever outbreak of New London, Connecticut. Because he practised at the dawn of the age of patent medicine, unfortunately his name also came to be associated with medical quackery. We argue that his contributions have been grossly underestimated. He compounded and vended medications - including bilious pills and bitters - that were gold standards of the day. Moreover, one preparation for treatment of kidney stones led to his sub-specialization in this field and was met with such success that its sale continued for nearly 100 years after his death. While a talented medical man, Lee also had a knack for business, finding success in trading, whaling and real estate. © The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

77 FR 17568 - Notice of Receipt of Petition for Decision That Nonconforming 2005 Ifor Williams LM85G Trailers...

Science.gov (United States)

2012-03-26

...-0030, Notice 1] Notice of Receipt of Petition for Decision That Nonconforming 2005 Ifor Williams LM85G... Safety Administration (NHTSA) of a petition for a decision that 2005 Ifor Williams LM85G trailers that... capable of being altered to comply with, all applicable FMVSS based on destructive test data or such other...

Afinidades seletivas: uma comparação entre as sociobiologias da literatura de Pierre Bourdieu e Raymond Williams Selective kinships: comparing the literarture sociologies od Pierre Bourdieu and Raymond Williams

Directory of Open Access Journals (Sweden)

Enio Passiani

2009-10-01

Full Text Available As sociologias da literatura de Bourdieu e Williams estão apoiadas em dois conceitos fundamentais: “habitus” e “estruturas de sentimento”, respectivamente. E é clara a semelhança entre eles: ambos tentam traduzir uma espécie de consciência prática adquirida pelos agentes sociais a partir de um processo particular de socialização. Para o primeiro, o “habitus” é internalizado na experiência vivida num campo específi co; ao passo que, para o segundo, tal consciência é formada no interior dos grupos culturais. Nesse sentido, ambas as noções dizem respeito a um conjunto de valores compartilhados que aproximam e afastam certos agentes uns dos outros, criando solidariedade e rivalidades. Esta comunicação pretende demonstrar que, apesar das diferenças que existem, os conceitos dos autores não supervalorizam nem a reprodução nem a mudança social, mas, ao contrário, tentam explicar esses fenômenos como jogo dialético. Palavras-chave: Pierre Bourdieu. Raymond Williams. Sociologia da literatura. “Habitus”. Estruturas de sentimento. The literature sociologies of Bourdieu and Williams are structured in two fundamental concepts: “habitus” and “sentiment structures”, respectively. It’s very clear the resemblance between them: both try to translate a kind of practical conscience, acquired by the social agents from a particular socializing process. To the fi rst, the “habitus” is internalized in the living experience of a specifi c fi eld; while that to the second that conscience is formed in the interior of cultural groups. In this sense, both ideas talk about shared values which approximate and withdraw some agents one from the others, creating solidarity and competition. This text intends to show that, despite of the existing differences, the authors concepts don’t overestimate neither the reproduction, nor the social change, but, otherwise, try to explain these phenomena as a dialectic game. Keywords

Sir William Osler's speech at Troy: a Trojan horse?

Science.gov (United States)

Moran, Michael E

2012-01-01

Troy, New York, is a city of 55,000 people in upstate New York located along the Hudson River. A city of surprisingly rich cultural heritage, it was the home of New York state's first hospital outside New York City. The 50th anniversary celebration of Troy's hospital brought William Osler to the city as the keynote speaker. This speech, delivered on November 28, 1900, is one of Sir William's less well known addresses. Osler began his comments with Sir Thomas More's Utopia and talked at length about the hospital, its obligations, the influences it has upon the community, and the role of physicians and surgeons. He broached one of his old saws, the salary of attending physicians and their needed role in hospital management. His words were published in the diamond jubilee's records, but the hospital did not outlive its prominent guest professor, and it closed its doors in 1914. Just like the great historical city of Troy, New York's own Troy was on the brink of decline, and its hospital would be the first fatality. Therefore, it is almost prescient that the words of Osler, taken into historical context juxtaposed against the socioeconomic forces at work, are akin to the Greek's offering of a wooden edifice to end the Trojan War.

Meteor Beliefs Project: some meteoric imagery in the works of William Shakespeare

Science.gov (United States)

McBeath, A.; Gheorghe, A. D.

2003-08-01

Passages from three of William Shakespeare's plays are presented, illustrating some of the beliefs in meteors in 16th-17th century England. They also reflect earlier beliefs and information which it is known Shakespeare drew on in constructing his works.

An Investigation into Semantic and Phonological Processing in Individuals with Williams Syndrome

Science.gov (United States)

Lee, Cheryl S.; Binder, Katherine S.

2014-01-01

Purpose: The current study examined semantic and phonological processing in individuals with Williams syndrome (WS). Previous research in language processing in individuals with WS suggests a complex linguistic system characterized by "deviant" semantic organization and differential phonological processing. Method: Two experiments…

Síndrome de Williams-Beuren. Enfoque diagnóstico a través del fenotipo

Directory of Open Access Journals (Sweden)

María Angelina Lacruz-Rengel

2015-10-01

Full Text Available Resumen (español El síndrome de Williams-Beuren es un trastorno genético del desarrollo neurológico que incluye diferentes manifestaciones clínicas como retardo en el crecimiento e intelectual, cardiopatía congénita y rasgo facial distintivo. El objetivo de este estudio es describir las características clínicas que conducen a su diagnóstico, conocer su evolución fenotípica y las medidas terapéuticas adecuadas. Se realizó un estudio retrospectivo, descriptivo, tipo serie de casos, en el que se incluyeron todos los pacientes con el diagnóstico de síndrome de Williams-Beuren, evaluados en el Instituto Autónomo Hospital Universitario de Los Andes, durante enero de 2000 a junio de 2014. El principal motivo de consulta fue la presencia de dismorfía facial y cardiopatía congénita, en la totalidad de los casos. La estenosis de la arteria pulmonar bilateral fue el tipo de cardiopatía congénita más frecuente en 4/7 pacientes. El síndrome de Williams-Beuren es una entidad genética que muestra un amplio espectro de características clínicas. Conocer todos estos hallazgos permite realizar el diagnóstico, ofrecer una adecuada atención médica, psicoterapéutica y educativa que permite mejorar su calidad de vida, sobrevida e inserción a la sociedad Abstract (english Williams-Beuren syndrome is a genetic neurodevelopmental disorder that includes different clinical manifestations as growth retardation and intellectual, congenital heart disease and distinctive facial features. The aim of this study was to describe the clinical features that leading to their diagnosis, know their phenotypic evolution and provide appropriate treatment. A retrospective, descriptive case series study, which included all patients with a diagnosis of Williams-Beuren syndrome, evaluated in the Autonomous Institute University Hospital of Los Andes, from January 2000 to June 2014 was performed. The main complaint was the presence of facial dysmorphic and

Adult scurvy in New France: Samuel de Champlain's "Mal de la terre" at Saint Croix Island, 1604-1605.

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Crist, Thomas A; Sorg, Marcella H

2014-06-01

Diagnosing scurvy (vitamin C deficiency) in adult skeletal remains is difficult despite documentary evidence of its past prevalence. Analysis of 20 European colonists buried at Saint Croix Island in New France during the winter of 1604-1605, accompanied by their leader Samuel de Champlain's eyewitness account of their symptoms, provided the opportunity to document lesions of adult scurvy within a tightly dated historical context. Previous diagnoses of adult scurvy have relied predominantly on the presence of periosteal lesions of the lower limbs and excessive antemortem tooth loss. Our analysis suggests that, when observed together, reactive lesions of the oral cavity associated with palatal inflammation and bilateral lesions at the mastication muscle attachment sites support the differential diagnosis of adult scurvy. Antemortem loss of the anterior teeth, however, is not a reliable diagnostic indicator. Employing a biocultural interpretive approach, analysis of these early colonists' skeletal remains enhances current understanding of the methods that medical practitioners used to treat the disorder during the Age of Discovery, performing rudimentary oral surgery and autopsies. Although limited by a small sample and taphonomic effects, this analysis strongly supports the use of weighted paleopathological criteria to diagnose adult scurvy based on the co-occurrence of specific porotic lesions. Copyright © 2014 Elsevier Inc. All rights reserved.

Shoreline oiling conditions in Prince William Sound following the Exxon Valdez oil spill

International Nuclear Information System (INIS)

Neff, J.M.; Owens, E.H.; Stoker, S.W.; McCormick, D.M.

1995-01-01

Following the Exxon Valdez oil spill of March 24, 1989, in Prince William Sound, Alaska, Exxon conducted comprehensive, systematic shoreline surveys in cooperation with federal and state authorities to obtain information on the distribution and magnitude of shoreline oiling and to identify natural and cultural resources requiring special protection. Similar joint surveys were performed during the springs of 1990, 1991, and 1992 on all Prince william Sound and Gulf of Alaska shorelines that were suspected of having remnants of weathered oil and that would benefit from further cleanup. In the springs of 1990, 1991, and 1992, isolated pockets of subsurface oil were found, chiefly in small scattered zones in coarse cobble/boulder sediments in the upper intertidal or supratidal zones. In 1991, about one-third of the subdivisions in Prince William Sound with surface oil also contained some subsurface oil. The areal extent of this subsurface oil declined by nearly 70% between 1991 and 1992, from about 37,000 m 2 to about 12,000 m 2 . Moreover, where subsurface oil remained in 1992, it was present in lesser amounts. Rates of oil removal were greatest on coastal sections treated early in the spring and summer of 1989. Where shoreline treatment was delayed, the subsequent rate of removal of oil from the shore by natural processes was slower. 27 refs., 10 figs., 3 tabs

Genes, language, and the nature of scientific explanations: the case of Williams syndrome.

Science.gov (United States)

Musolino, Julien; Landau, Barbara

2012-01-01

In this article, we discuss two experiments of nature and their implications for the sciences of the mind. The first, Williams syndrome, bears on one of cognitive science's holy grails: the possibility of unravelling the causal chain between genes and cognition. We sketch the outline of a general framework to study the relationship between genes and cognition, focusing as our case study on the development of language in individuals with Williams syndrome. Our approach emphasizes the role of three key ingredients: the need to specify a clear level of analysis, the need to provide a theoretical account of the relevant cognitive structure at that level, and the importance of the (typical) developmental process itself. The promise offered by the case of Williams syndrome has also given rise to two strongly conflicting theoretical approaches-modularity and neuroconstructivism-themselves offshoots of a perennial debate between nativism and empiricism. We apply our framework to explore the tension created by these two conflicting perspectives. To this end, we discuss a second experiment of nature, which allows us to compare the two competing perspectives in what comes close to a controlled experimental setting. From this comparison, we conclude that the "meaningful debate assumption", a widespread assumption suggesting that neuroconstructivism and modularity address the same questions and represent genuine theoretical alternatives, rests on a fallacy.

La Fondation William et Flora Hewlett | CRDI - Centre de recherches ...

International Development Research Centre (IDRC) Digital Library (Canada)

La Fondation William et Flora Hewlett. http://www.hewlett.org/. Initiative Think tank. Cette initiative permet d'établir des organismes indépendants qui se consacrent à la recherche et à l'élaboration de politiques dans des pays en développement. Voir davantage. Initiative Think tank. Croissance de l'économie et débouchés ...

Case report of sudden death in a child with Williams syndrome ...

African Journals Online (AJOL)

Williams syndrome is a neurodevelopmental disorder characterized by distinctive personality traits, facial features (so called “elfin face”) and cardiac abnormalities, of which supravalvular aortic stenosis is the most common lesion found. The cause is a deletion of a group of genes on chromosome 7q11.23. Administration of ...

William Golding's Iconoclastic Views about the Neanderthal Man in "The Inheritors"

Science.gov (United States)

Youssef, Sayed Mohammed

2016-01-01

William Golding has been identified as a nonconformist whose opinions always go contrary to what is customarily accepted or established. This is shown in all his novels, more specifically "The Inheritors", in which he defies long established opinions held by anthropologists, historians, archaeologists as well as many others about the…

Climatic data for Williams Lake, Hubbard County, Minnesota, 1982

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Rosenberry, D.O.; Sturrock, A.M.; Scarborough, J.L.; Winter, T.C.

1988-01-01

Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Those climatic data needed for energy budget and mass transfer studies are presented , including: water surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Some calculated values necessary for these studies are also presented, such as vapor pressure and Bowen-ratio values. Data are collected at raft and land stations.

Climatic data for Williams Lake, Hubbard County, Minnesota, 1986

Science.gov (United States)

Rosenberry, D.O.; Sturrock, A.M.; Winter, T.C.

1988-01-01

Research on the hydrology of Williams Lake, north-central Minnesota includes study of evaporation. Presented here are those climatic data needed for energy-budget and mass-transfer studies, including: water-surface temperature, dry-bulb and wet-bulb air temperatures, wind speed, precipitation, and solar and atmospheric radiation. Some calculated values necessary for these studies, such as vapor pressure and Bowen ratio numbers, also are presented. Data are collected at raft and land stations.

Centennial ties: Harvey Cushing (1869-1939) and William Osler (1849-1919) on Andreas Vesalius (1514-1564).

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Toodayan, Nadeem

2017-08-01

Andreas Vesalius is often regarded as the founding father of modern anatomical study. The quincentennial anniversary of his birth - 31 December 2014 - has been very widely commemorated, and it is the purpose of this article to contrast these celebrations with what happened during the Vesalius quatercentenary year of 1914. More specifically, we look at how Vesalius was perceived a century ago by examining his influence on two of western medicine's most iconic gentlemen - Harvey Williams Cushing (1869-1939) and his larger than life mentor, Sir William Osler (1849-1919).

Description of common musculoskeletal findings in Williams Syndrome and implications for therapies.

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Copes, L E; Pober, B R; Terilli, C A

2016-07-01

Williams syndrome (WS), also referred to as Williams-Beuren syndrome (WBS), is a relatively rare genetic disorder affecting ∼1/10,000 persons. Since the disorder is caused by a micro-deletion of ∼1.5 Mb, it is not surprising that the manifestations of WS are extremely broad, involving most body systems. In this paper, we primarily focus on the musculoskeletal aspects of WS as these findings have not been the subject of a comprehensive review. We review the MSK features commonly seen in individuals with WS, along with related sensory and neurological issues interacting with and compounding underlying MSK abnormalities. We end by providing perspective, particularly from the vantage point of a physical therapist, on therapeutic interventions to address the most common MSK and related features seen in WS. Clin. Anat. 29:578-589, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Simulasi Perdagangan Saham PT Tambang Batubara Bukit Asam, Tbk. dengan Macd dan Williams % Range

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Benny Benny

2010-11-01

Full Text Available Moving Average Convergence Divergence (MACD is a momentum indicator to determine the indication of the trend reversal point. Williams% Range is also a momentum indicator that can provide when reversal trend will occur. This analysis will use the data movement of stock prices for PT Tambang Coal Bukit Asam Tbk. (PTBA. PTBA stock prices are influenced by fundamental conditions such as limited supply of fuel which is rumored and coal is the main alternative fuels other than oil. Study period was 241 trade days. Data are analyzed in several periods and then fitted with the MACD indicator and Williams % R, then simulate the trade during the period of research studies to determine the level of trading profits or losses based on the combination of both these technical indicators. The conclusion of this analysis, the MACD is an indicator that is considered slow (lagging in giving an indication of weakness, but in reverse the MACD is considered to provide an accurate indication of where the indication given is rarely wrong. Williams% R is an rapid indicator in anticipation of a reversal trend, but these indicators often give a false indication since this indicator is quite sensitive to the movement of stock prices goings go up or down. 

Validação do escore ultra-sonográfico de Williams para o diagnóstico da hepatopatia da fibrose cística Validation of the Williams ultrasound scoring system for the diagnosis of liver disease in cystic fibrosis

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Eleonora D. T. Fagundes

2004-01-01

Full Text Available OBJETIVOS: Descrever as alterações hepáticas observadas ao exame ultra-sonográfico de fibrocísticos do Ambulatório de Fibrose Cística do Hospital das Clínicas da UFMG, comparar os achados ultra-sonográficos com critérios clínicos e bioquímicos e validar o escore de Williams para o diagnóstico de hepatopatia associada à fibrose cística. MÉTODOS: Setenta fibrocísticos foram acompanhados prospectivamente e submetidos a exame clínico, bioquímico e ultra-sonográfico. Os achados ultra-sonográficos foram comparados com os resultados do exame clínico e bioquímico. Para a validação do escore ultra-sonográfico de Williams, os critérios clínicos e bioquímicos foram utilizados como padrão-ouro. Foram calculados sensibilidade, especificidade, valor preditivo positivo e valor preditivo negativo do escore de Williams. Para os cálculos, os pacientes foram divididos em dois grupos: normal ao exame ultra-sonográfico (escore = 3 ou alterado (escore > 3. RESULTADOS: Dez pacientes preencheram os critérios clínicos e/ou bioquímicos para hepatopatia (14,3%. Todos os pacientes hepatopatas segundo os critérios clínicos e/ou bioquímicos apresentavam alguma alteração ao exame ultra-sonográfico. As alterações do parênquima hepático, borda hepática e fibrose periportal foram encontradas mais freqüentemente entre os hepatopatas, com diferença estatisticamente significativa. O escore de Williams apresentou alta especificidade (91,7%; IC 80,9-96,9, mas baixa sensibilidade (s = 50%; IC 20,1-79,9 para o diagnóstico da hepatopatia. CONCLUSÕES: O escore de Williams não constituiu um bom exame de triagem quando comparado ao exame clínico e bioquímico. Uma vez que ainda não há nenhum teste que, utilizado isoladamente, apresente sensibilidade adequada, é recomendável a utilização conjunta dos exames clínico, bioquímico e ultra-sonográfico no diagnóstico da hepatopatia associada à fibrose cística, sempre em avalia

The Recurring Author: William Shakespeare, a Case Study through Content Analysis.

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Harrison, Robert L., Jr.

The "recurring author" is one whose works appear many times at different levels in instructional units found in literature textbook series. A descriptive case study discussed the treatment of a recurring author, William Shakespeare, using units in a sample of six literature textbook series. Developed to describe, to code, and to analyze…

Prosodic Abilities of Spanish-Speaking Adolescents and Adults with Williams Syndrome

Science.gov (United States)

Martinez-Castilla, Pastora; Sotillo, Maria; Campos, Ruth

2011-01-01

In spite of the relevant role of prosody in communication, and in contrast with other linguistic components, there is paucity of research in this field for Williams syndrome (WS). Therefore, this study performed a systematic assessment of prosodic abilities in WS. The Spanish version of the Profiling Elements of Prosody in Speech-Communication…

Diurnal Cortisol Profile in Williams Syndrome in Novel and Familiar Settings

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Lense, Miriam Diane; Tomarken, Andrew J.; Dykens, Elisabeth M.

2013-01-01

Williams syndrome (WS) is a neurodevelopmental genetic disorder associated with high rates of anxiety and social issues. We examined diurnal cortisol, a biomarker of the stress response, in adults with WS in novel and familiar settings, and compared these profiles to typically developing (TD) adults. WS and TD participants had similar profiles in…

William Gaddis’s Immortality: Celebration, Cartoon, or Corruption?

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Crystal Alberts

2013-11-01

Full Text Available Although ostensibly a review of 'The Letters of William Gaddis' edited by Steven Moore (Champaign: Dalkey Archive, 2013, this article evaluates Moore’s volume in light of generally accepted practices of scholarly editions and the handling of historical documents. In particular, Alberts compares some of Moore’s edited letters to the originals housed either at Washington University in St. Louis or the Harry Ransom Center at the University of Texas, Austin and reveals issues involving the representation of the archival material, inconsistencies in editorial principles, and a misattributed letter, among other things.

WILLIAM HAZLITT, OBSESSIVE LOVE, AND LIBER AMORIS.

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Trosman, Harry

2017-07-01

William Hazlitt, a distinguished literary figure of the early nineteenth century and a forerunner of psychoanalytic insights, had a keen awareness of the impact of the imagination on assessing works of art. At forty-two, he became hopelessly involved in an obsessive love affair with a nineteen-year-old woman and could not extricate himself from the relationship. The affair followed the death of his father, a powerful influence on his life. Factors in his obsessive love included finding an object of idealization subject to his imaginative creation and narcissistically reexperiencing himself about to begin a new life. © 2017 The Psychoanalytic Quarterly, Inc.

Featural versus configural face processing in a rare genetic disorder: Williams syndrome

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Isaac, L.; Lincoln, A.

2011-01-01

Background Williams syndrome (WMS) is a rare genetic disorder with an estimated prevalence of 1 in 20 000 live births. Among other characteristics, WMS has a distinctive cognitive profile with spared face processing and language skills that contrasts with impairment in the cognitive domains of

John Whitridge Williams, MD (1866–1931) of Baltimore: pioneer of academic obstetrics

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Dunn, P M

2007-01-01

Williams was the founder of academic obstetrics in the United States and with his textbook was the recognised leader of this discipline in America during the first 30 years of the 20th century. PMID:17185435

William J. Donovan: Visionary, Strategic Leader, an Historical Perspective

Science.gov (United States)

1991-05-03

War II years until his death . 1945 through 1959. Strategy, without Information on which It can rely, is helpless. Information Is useless unless It Is...was again emulating his Rough Rider hero, because like him, he was now a cavalryman.32 Donovan had never been a horseman or soldier before, but like...Intelligence officer and Chief of Combined Operatlrns during World War II, said of General William Donovan In 1966, seven years after his death , "This

OBITUARY: Sir William Mitchell Physicist and enthusiast for science

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Cowley, R

2002-01-01

"William Mitchell was successively head of Physics at Reading and Oxford universities, and Chairman of the Science and Engineering Research Council from 1985 to 1990. He is largely responsible for the excellent neutron and X-ray facilities that are available for research by scientists in the UK. He was one of the first to realise that these uniquely powerful facilities would be essential tools not only for physicists but also for chemists, biologists, materials scientists and engineers" (1 page).

Sleep EEG Fingerprints Reveal Accelerated Thalamocortical Oscillatory Dynamics in Williams Syndrome

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Bodizs, Robert; Gombos, Ferenc; Kovacs, Ilona

2012-01-01

Sleep EEG alterations are emerging features of several developmental disabilities, but detailed quantitative EEG data on the sleep phenotype of patients with Williams syndrome (WS, 7q11.23 microdeletion) is still lacking. Based on laboratory (Study I) and home sleep records (Study II) here we report WS-related features of the patterns of…

Toddlers with Williams Syndrome Process Upright but Not Inverted Faces Holistically

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Cashon, Cara H.; Ha, Oh-Ryeong; DeNicola, Christopher A.; Mervis, Carolyn B.

2013-01-01

Holistic processing of upright, but not inverted, faces is a marker of perceptual expertise for faces. This pattern is shown by typically developing individuals beginning at age 7 months. Williams syndrome (WS) is a rare neurogenetic developmental disorder characterized by extreme interest in faces from a very young age. Research on the effects of…

William Whewell, Galileo, and reconceptualizing the history of science and religion.

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Wilson, David B

2011-12-20

This paper advocates a reconceptualization of the history of science and religion. It is an approach to the subject that would aid research by historians of science as well as their message to others, both academic and non-academic. The approach is perfectly illustrated by the life and ideas of William Whewell and Galileo.

Audiological follow-up of 24 patients affected by Williams syndrome.

Science.gov (United States)

Barozzi, Stefania; Soi, Daniela; Spreafico, Emanuela; Borghi, Anna; Comiotto, Elisabetta; Gagliardi, Chiara; Selicorni, Angelo; Forti, Stella; Cesarani, Antonio; Brambilla, Daniele

2013-09-01

Williams syndrome is a neurodevelopmental disorder associated with cardiovascular problems, facial abnormalities and several behavioural and neurological disabilities. It is also characterized by some typical audiological features including abnormal sensitivity to sounds, cochlear impairment related to the outer hair cells of the basal turn of the cochlea, and sensorineural or mixed hearing loss, predominantly in the high frequency range. The aim of this report is to describe a follow-up study of auditory function in a cohort of children affected by this syndrome. 24 patients, aged 5-14 years, were tested by means of air/bone conduction pure-tone audiometry, immittance test and transient evoked otoacoustic emissions. They were evaluated again 5 years after the first assessment, and 10 of them underwent a second follow-up examination after a further 5 years. The audiometric results showed hearing loss, defined by a pure tone average >15 dB HL, in 12.5% of the participants. The incidence of hearing loss did not change over the 5-year period and increased to 30% in the patients who underwent the 10-year follow-up. Progressive sensorineural hearing loss was detected in 20% of the patients. A remarkable finding of our study regarded sensorineural hearing impairment in the high frequency range, which increased significantly from 25% to 50% of the participants over the 5-year period. The increase became even more significant in the group of patients who underwent the 10-year follow-up, by which time the majority of them (80%) had developed sensorineural hearing loss. Otoacoustic emissions were found to be absent in a high percentage of patients, thus confirming the cochlear fragility of individuals with Williams syndrome. Our study verified that most of the young Williams syndrome patients had normal hearing sensitivity within the low-middle frequency range, but showed a weakness regarding the high frequencies, the threshold of which worsened significantly over time in

Williams syndrome and its cognitive profile: the importance of eye movements

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Van Herwegen J

2015-06-01

Full Text Available Jo Van Herwegen Department of Psychology, Kingston University London, Surrey, UK Abstract: People with Williams syndrome (WS, a rare neurodevelopmental disorder that is caused by a deletion on the long arm of chromosome 7, often show an uneven cognitive profile with participants performing better on language and face recognition tasks, in contrast to visuospatial and number tasks. Recent studies have shown that this specific cognitive profile in WS is a result of atypical developmental processes that interact with and affect brain development from infancy onward. Using examples from language, face processing, number, and visuospatial studies, this review evaluates current evidence from eye-tracking and developmental studies and argues that domain general processes, such as the ability to plan or execute saccades, influence the development of these domain-specific outcomes. Although more research on eye movements in WS is required, the importance of eye movements for cognitive development suggests a possible intervention pathway to improve cognitive abilities in this population. Keywords: Williams syndrome, eye movements, face processing, language, number, visuospatial abilities

The products of intertextuality: The value of student adaptations in a literature course

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Misty Krueger

2015-09-01

Full Text Available The essay explores a pedagogy of adaptation that focuses on examining intertextuality and engaging students in textual production through the creation of an adaptation. The paper discusses the success of assigning an adaptation project in an upper-level, third-year literature course taught at a small university. It examines student adaptations of writings by William Shakespeare, Jane Austen, Samuel Richardson, Henry Fielding, Mary Shelley, and Ben H. Winters and of existing film adaptations of Sense and Sensibility and Frankenstein. I link student projects to critical concepts such as re-vision and multimodality, and disciplines such as literary studies and the digital humanities. I also analyze how the projects reflect students' interests in popular culture and fandom.

Physics in Literature

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Manos, Harry

2014-01-01

Physics offers a cross-discipline perspective to understanding other subjects. The purpose of this paper is to provide examples of physics in literature that physics and astronomy teachers can use to give students an indication of the relevance of science as depicted in the humanities. It is not possible to cite the thousands of examples available. I have tried to select authors whom students would be reading in high school and in college undergraduate English classes: in particular Joseph Conrad, Samuel Taylor Coleridge, William Shakespeare, H. G. Wells, Fyodor Dostoevsky, Norman Mailer, and an author currently in vogue, Dan Brown. I am sure many reading this article will come up with their own examples.

Williams Syndrome and Anesthesia for Non-cardiac Surgery: High Risk Can Be Mitigated with Appropriate Planning.

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Brown, Morgan L; Nasr, Viviane G; Toohey, Rebecca; DiNardo, James A

2018-03-23

Patients with Williams syndrome are considered at high risk for anesthesia-related adverse events. At our institution, all William syndrome patients undergoing cardiac surgical, cardiac catheterization/interventional procedures, and cardiac imaging studies are cared for by cardiac anesthesiologists. All William syndrome patients undergoing non-cardiac surgical, interventional, or imaging studies are cared for by main operating room pediatric anesthesiologists with consultative input from a cardiac anesthesiologist. We reviewed our experience with 75 patients undergoing 202 separate anesthetics for 95 non-cardiac procedures and 107 cardiac procedures from 2012 to 2016. The mean age was 7.5 ± 7.0 years and the mean weight was 22.3 ± 17.0 kg. One hundred and eighty-seven patients had a general anesthetic (92.6%). Medications used included etomidate in 26.2%, propofol in 37.6%, isoflurane in 47.5%, and sevoflurane in 68.3%. Vasopressors and inotropes were required including calcium (22.8%), dopamine (10.4%), norepinephrine (17.3%), phenylephrine (35.1%), vasopressin (0.5%), and ephedrine (5.4%). The median length of stay after anesthesia was 2.8 days (range 0-32). No adverse events occurred in 89.6% of anesthetics. There were two cases of cardiac arrest, one of which required extracorporeal life support for resuscitation. Of the non-cardiac surgical procedures, 95.7% did not have a cardiovascular adverse event. Patients with Williams syndrome are at high risk for anesthesia, especially when undergoing cardiac procedures. The risk can be mitigated with appropriate planning and adherence to the hemodynamic goals for non-cardiac surgical procedures.

Percutaneous CT-guided high frequency induced thermotherapy as a treatment hepatocellular carcinoma and hepatic metastatic lesions

International Nuclear Information System (INIS)

Lu Ligong; Luo Pengfei; Chen Xiaoming

2004-01-01

Objective: To analyze the efficacy, side effects and complications of percutaneous high frequency induced thermotherapy (HiTT) performed under CT guidance involving 36 patients with hepatocellular carcinomas (HCC) and hepatic metastatic lesions. Methods: HiTT was performed in treatment of 36 patients (24 men and 12 women) with 42 hepatocellular carcinoma and hepatic metastatic carcinoma (six patient out of 36 had two nidi). The diameter of the tumors ranged from 1.6 to 7.8 cm (mean, 3.2 cm). The efficacy of HiTT was evaluated with triphasic spiral CT performed 1 month after the procedure. Results: The post-treatment CT scan showed complete necrosis in 33 nidi (78%) out of 42 nidi of hepatocellular carcinoma and hepatic metastatic carcinoma in 30 patients out of 36. Complete necrosis was obtained in 18 (95%) of 19 tumors no larger than 3 cm in diameter, 13 (72%) of 18 tumors between 3.0 and 5.0 cm in diameter. Eleven tumors showed incomplete necrosis. In our study, none of the patients experienced severe complications. All the patients are alive in the follow-up ranging from 2 to 12 months (mean, 7 months). Conclusion: Our research suggests that HiTT can be a safe and effective treatment of hepatocellular carcinomas and hepatic metastatic carcinoma when the lesion is no larger than 3 cm. The treatment is relatively effective for hepatocellular carcinoma between 3 and 5 cm in size. (authors)

William Harvey & Capillaries: Can You "Discover" Circulation without Connections between Arteries & Veins?

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Allchin, Douglas

2005-01-01

William Harvey's discovery of the presence of capillaries and the role played by them without actually seeing them highlights his power of observation and logic. However, his perspective could not be considered as new since he had adopted his disposition for ocular demonstration from Aristotle and Galen.

Perceiving Facial and Vocal Expressions of Emotion in Individuals with Williams Syndrome

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Plesa-Skwerer, Daniela; Faja, Susan; Schofield, Casey; Verbalis, Alyssa; Tager-Flusberg, Helen

2006-01-01

People with Williams syndrome are extremely sociable, empathic, and expressive in communication. Some researchers suggest they may be especially sensitive to perceiving emotional expressions. We administered the Faces and Paralanguage subtests of the Diagnostic Analysis of Nonverbal Accuracy Scale (DANVA2), a standardized measure of emotion…

Drug-Coated Balloon Angioplasty: A Novel Treatment for Pulmonary Artery In-Stent Stenosis in a Patient with Williams Syndrome.

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Cohen, Jennifer L; Glickstein, Julie S; Crystal, Matthew A

2017-12-01

A 20-month-old boy with Williams syndrome had undergone multiple surgical and catheter-based interventions for resistant peripheral pulmonary arterial stenoses with eventual bilateral stent placement and conventional balloon angioplasty. He persistently developed suprasystemic right ventricular (RV) pressure. Angioplasty with a drug-coated balloon (DCB) was performed for in-stent restenosis and to remodel his distal pulmonary vessels bilaterally. This resulted in immediate improvement in the in-stent stenosis and resultant decrease in RV pressure. Follow-up catheterization two months later continued to show long-lasting improvement in the in-stent stenosis. We hypothesize that the anti-proliferative effects of DCBs may be of benefit in the arteriopathy associated with Williams syndrome. We report this as a novel use of a DCB in the pulmonary arterial circulation in a patient with Williams syndrome.

Samuel P. Massie Chair of Excellence In Environmental Disciplines: Hampton University 1994-2010 Year Report

Energy Technology Data Exchange (ETDEWEB)

Adeyiga, Adeyinka A. [Hampton Univ., Hampton, VA (United States). School of Engineering and Technology

2014-12-17

The establishment of the DOE-EM Dr. Samuel P. Massie Chair of Excellence provides an excellent opportunity for Hampton University to be involved in key environmental issues in the 21^st Century. The main areas of focus are on: 1. Coal gasification with respect to pollution prevention and reduction. 2. Solid waste treatment through bioremediation technology and 3. Industrial wastewater treatment Synthesizing ion catalysts suitable for use in slurry bubble column reaction was carried out. Construction of an autoclave continuous stirred tank reactor has been completed. At the initial stage of the development of this program, work was conducted in the area of formic acid recovery from waste streams, which yielded useful results. We also succeeded in the removal of priority metal ions such as cadmium, chromium, copper, lead, mercury, nickel, silver, thallium, zinc, etc., from industrial and municipal wastewater by using natural wastes. The process uses tree leaves to adsorb the metal ions in the wastewater. The ultimate goal is to develop inexpensive, highly available, effective metal ion adsorbents from natural wastes as an alternative to existing commercial adsorbents, and also to explain the possible adsorption mechanism that is taking place. This technology uses natural wastes to eliminate other wastes. Obviously, there are several advantages: (1) the negative impact on environment is eliminated, (2) the complicated regeneration step is not needed, and (3) the procedure saves money and energy. Twelve different types of leaves have been tested with lead, zinc, and nickel. The study mechanism showed that the leaf tannin is an active ingredient in the adsorption of metal ions. The ion-exchange mechanism controlled the adsorption process.

Cognitive-behavioral phenotypes of Williams syndrome are associated with genetic variation in the GTF2I gene, in a healthy population.

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Crespi, Bernard J; Hurd, Peter L

2014-11-28

Individuals with Williams syndrome, a neurogenetic condition caused by deletion of a set of genes at chromosomal location 7q11.23, exhibit a remarkable suite of traits including hypersociality with high, nonselective friendliness and low social anxiety, expressive language relatively well-developed but under-developed social-communication skills overall, and reduced visual-spatial abilities. Deletions and duplications of the Williams-syndrome region have also been associated with autism, and with schizophrenia, two disorders centrally involving social cognition. Several lines of evidence have linked the gene GTF2I (General Transcription Factor IIi) with the social phenotypes of Williams syndrome, but a role for this gene in sociality within healthy populations has yet to be investigated. We genotyped a large set of healthy individuals for two single-nucleotide polymorphisms in the GTF2I gene that have recently been significantly associated with autism, and thus apparently exhibit functional effects on autism-related social phenotypes. GTF2I genotypes for these SNPs showed highly significant association with low social anxiety combined with reduced social-communication abilities, which represents a metric of the Williams-syndrome cognitive profile as described from previous studies. These findings implicate the GTF2I gene in the neurogenetic basis of social communication and social anxiety, both in Williams syndrome and among individuals in healthy populations.

Tietoa kosketuksen päässä : NFC-teknologia innovatiivisten käyttötapausten kautta

OpenAIRE

Toivanen, Sanna

2012-01-01

Opinnäytetyöni tutkii vähittäiskauppaa, NFC-teknologiaa, sekä innovointia prosessien kautta käytäntöön. Tavoitteena oli löytää uusia ideoita NFC-teknologian käyttöön, pää-asiassa vähittäiskauppakontekstissa. Työn tutkimuksellinen osuus koostuu tutkimus-haastatteluista, innovaatiotyöpajoista, sekä kirjallisuuskatsauksesta edellä mainittuihin aiheisiin liittyen. NFC tulee sanoista Near Field Communication ja suomeksi se on kääntynyt lähitunnis-tamiseksi tai lähitunnistusteknologiaksi. NFC-t...

Lähtugem ehitistest! / William J. R. Curtis ; interv. Andres Kurg, Karin Hallas, Triin Ojari

Index Scriptorium Estoniae

Curtis, William J. R.

1998-01-01

24. apr. pidas Rotermanni soolalaos loengu arhitektuuriajaloolane William J. R. Curtis. Katkeid jutuajamisest W. Curtisega. Arhitektuurikriitikast, oma raamatust "Modern Architecture since 1900", millest W. Curtis praegu kriitikuna kirjutab, Lille'i projektist jm

Parents perceptions of social inclusion for children with Williams Syndrome

OpenAIRE

Gulliver, Katherine

2016-01-01

This thesis explores parents’ perceptions of social inclusion for children with Williams Syndrome; a rare intellectual disability with a distinct social cognitive profile. 5 interviews with parents give rich understanding to what parents’ value for their child’s education, and how this is achieved. Thematic analysis highlights key similarities and differences in experiences between parents of children attending mainstream schools and one special school. Severity of disability affects how pare...

Morphological differences in the mirror neuron system in Williams Syndrome

OpenAIRE

Ng, Rowena; Brown, Timothy T.; Erhart, Matthew; Järvinen, Anna M.; Korenberg, Julie R.; Bellugi, Ursula; Halgren, Eric

2015-01-01

Williams syndrome (WS) is a genetic condition characterized by an overly gregarious personality, including high empathetic concern for others. Although seemingly disparate from the profile of autism spectrum disorder (ASD), both are associated with deficits in social communication/cognition. Notably, the mirror neuron system (MNS) has been implicated in social dysfunction for ASD; yet, the integrity of this network and its association with social functioning in WS remains unknown. Magnetic re...

The Impact of Personality on History: An Interview with William L. Shirer.

Science.gov (United States)

Social Education, 1983

1983-01-01

William L. Shirer, author of Rise and Fall of the Third Reich, discusses a wide variety of subjects, including the personalities of Roosevelt and Hitler, why the Germans succumbed to Nazism, McCarthyism in the United States, and the heroic resistance of the Russians to German invasion. (CS)

The Production of Figurative Language in Typically Developing Children and Williams Syndrome

Science.gov (United States)

Naylor, Lauren; Van Herwegen, Jo

2012-01-01

The current study investigated the development of figurative language production, including different types of figurative expressions, during a fictional narrative in 20 typically developing (TD) children and 20 children with Williams syndrome (WS) aged 7-18 years old. In contrast to previous studies, developmental trajectories showed that (1) the…

A Comparison between Linguistic Skills and Socio-Communicative Abilities in Williams Syndrome

Science.gov (United States)

Alfieri, P.; Menghini, D.; Marotta, L.; De Peppo, L.; Ravà, L.; Salvaguardia, F.; Varuzza, C.; Vicari, S.

2017-01-01

Background: Individuals with Williams syndrome (WS) show a disharmonic linguistic profile with a clear pattern of strengths and weaknesses. Despite their sociable nature, atypical socio-communicative abilities and deficits in communication and relationship with others have been found. Aim: The aim of the present study was to investigate whether…

Evaluation of a Stranger Safety Training Programme for Adults with Williams Syndrome

Science.gov (United States)

Fisher, M. H.

2014-01-01

Background: Individuals with Williams syndrome (WS) are reported to display increased sociability towards strangers, leading to increased social vulnerability. No research has examined real life interactions of adults with WS towards strangers and no interventions have been implemented to teach stranger safety skills to this population. Method:…

Contrast-Marking Prosodic Emphasis in Williams Syndrome: Results of Detailed Phonetic Analysis

Science.gov (United States)

Ito, Kiwako; Martens, Marilee A.

2017-01-01

Background: Past reports on the speech production of individuals with Williams syndrome (WS) suggest that their prosody is anomalous and may lead to challenges in spoken communication. While existing prosodic assessments confirm that individuals with WS fail to use prosodic emphasis to express contrast, those reports typically lack detailed…

“Sou feito de palavras”: A(s voz(es narrativa(s em O Inominável de Samuel Beckett

Directory of Open Access Journals (Sweden)

Lucianno Gatti

2016-02-01

Full Text Available O artigo discute a questão da voz narrativa no romance O inominável de Samuel Beckett. Com base em estudos genéticos da composição do romance, discute-se a função literária de temas como a crítica à linguagem e à consciência, assim como suas consequências para se pensar o gênero do romance. O artigo retoma então uma discussão sobre realismo em textos de Adorno e Lukács com o intuito de debater a centralidade da fábula, sua estrutura temporal e a relação da forma com a experiência histórica. Por fim, tentaremos retomar essas questões a partir da análise de um momento específico do romance de Beckett. Com isso, as questões teóricas anteriormente expostas deverão ganhar concretude no esforço de elucidar problemas da composição do romance, como o feitio episódico do conjunto, a identidade da voz narrativa, a especificidade do monólogo interior e a confluência entre narrativa e reflexão.

Random Thoughts on William Shakespeare and Medicine

Directory of Open Access Journals (Sweden)

KV Sahasranam

2017-04-01

Full Text Available Medicine and literature have always been connected over the ages. William Shakespeare (1564-1616 is no exception. There are plenty of references to medicine and diseases in the works of Shakespeare. The knowledge which Shakespeare has of medical conditions is much more than is expected of a common man. This is attributed to his association with practitioners of his time and reading of contemporary texts in medicine. Also his son in law Dr. John Hall who married Susanna, Shakespeare's eldest daughter would have contributed substantially to the knowledge of medicine in Shakespeare's compositions. Surgery at the Elizabethan times was well known and is reflected to a large extent in his plays.

Spatial-Sequential and Spatial-Simultaneous Working Memory in Individuals with Williams Syndrome

Science.gov (United States)

Lanfranchi, Silvia; De Mori, Letizia; Mammarella, Irene C.; Carretti, Barbara; Vianello, Renzo

2015-01-01

The aim of the present study was to compare visuospatial working memory performance in 18 individuals with Williams syndrome (WS) and 18 typically developing (TD) children matched for nonverbal mental age. Two aspects were considered: task presentation format (i.e., spatial-sequential or spatial-simultaneous), and level of attentional control…

Patterns and Trajectories in Williams Syndrome: The Case of Visual Orientation Discrimination

Science.gov (United States)

Palomares, Melanie; Englund, Julia A.; Ahlers, Stephanie

2011-01-01

Williams Syndrome (WS) is a developmental disorder typified by deficits in visuospatial cognition. To understand the nature of this deficit, we characterized how people with WS perceive visual orientation, a fundamental ability related to object identification. We compared WS participants to typically developing children (3-6 years of age) and…

Factor Structure of the Children's Behavior Questionnaire in Children with Williams Syndrome

Science.gov (United States)

Leyfer, Ovsanna; John, Angela E.; Woodruff-Borden, Janet; Mervis, Carolyn B.

2012-01-01

To examine the factor structure of temperament in 5-10-year-olds with Williams syndrome, an exploratory factor analysis was conducted on the responses of parents of 192 children on the children's behavior questionnaire. Four factors were identified. Two corresponded to factors reported for typically developing children: effortful control and…

Severity of Hyperacusis Predicts Individual Differences in Speech Perception in Williams Syndrome

Science.gov (United States)

Elsabbagh, M.; Cohen, H.; Cohen, M.; Rosen, S.; Karmiloff-Smith, A.

2011-01-01

Background: Williams Syndrome (WS) is a neurodevelopmental disorder of genetic origin, characterised by relative proficiency in language in the face of serious impairment in several other domains. Individuals with WS display an unusual sensitivity to noise, known as hyperacusis. Methods: In this study, we examined the extent to which hyperacusis…

John Chalmers DaCosta (1863-1933): restoration of the old operating table.

Science.gov (United States)

Peters, Madalyn G; Berger, Adam C; Schwartz, Gordon F; Yeo, Charles J; Cowan, Scott W

2013-03-01

John Chalmers DaCosta was an influential chairman and the first Samuel D. Gross Professor of Surgery at Jefferson Medical College in Philadelphia. He was well known throughout the field as a skilled surgeon, passionate speaker, and exceptional writer. In addition to countless accomplishments during his career, DaCosta was deeply dedicated to the preservation and commemoration of surgical history. This ideology was exemplified when he set out on a mission to recover the old wooden operating table used by many of his iconic mentors including Samuel D. Gross, Joseph Pancoast, and William W. Keen. This table was originally used for surgical demonstrations and anatomy lessons in a lecture room of the Ely Building and later in the great amphitheater of the Jefferson Sansom Street Hospital. It was found forgotten in the basement of the College Building and was promptly refurbished, donned with dedicatory plaques, and returned to its honored position in the medical college. Dr. DaCosta also contributed a detailed article recalling the history of the table and the notable leaders in surgery who taught and practiced on its surface. The old table currently stands proudly in the entranceway of the Department of Surgery where it will remain as a cherished symbol of the early beginnings of surgical practice and education.

Forasteiros na pátria-mãe: o lugar do migrante em The Lonely Londoners, de Samuel Selvon e The Final Passage, de Caryl Phillips

Directory of Open Access Journals (Sweden)

Denise Almeida Silva

2008-01-01

Full Text Available http://dx.doi.org/10.5007/2175-8026.2008n54p39 Este estudo analisa a construção ficcional da identidade do migrante em The Lonely Londoners (1956, de Samuel Selvon e The Final Passage (1985, de Caryl Phillips. Ambos os romances enfocam a experiência da geração Windrush, recrutada das colônias para suprir mão de obra na Inglaterra do pós-guerra. Ressalta-se o espaço intersticial ocupado pelas comunidades migrantes, e estuda-se a construção da identidade nessas obras dentro do contexto das relações culturais, analisando-se as políticas de afiliação, pertencimento e exclusão implícitas na formação dessas comunidades diaspóricas.

William Healy, M.D., Father of the American Child Guidance Movement

Science.gov (United States)

1981-08-01

courts, was another important development, starting in 1899. Meyer, Sigmund Freud , and Healy all contributed to the next step, which coupled the...Dummer Papers lists 454 correspondents. The prominent psychiatrists include: Franz Alexander, Trigant Burrow, Havelock Ellis, Flanders Dunbar, Sigmund ... Freud , Roy Grinker, William Healy, Karen Homey, Marion E. Kenworthy, Lawson Lowrey, Julse Masserman, Karl Menninger, Adolf Meyer, Smith Ely Jelliffe

Time–frequency analysis of nonstationary complex magneto-hydro-dynamics in fusion plasma signals using the Choi–Williams distribution

International Nuclear Information System (INIS)

Xu, L.Q.; Hu, L.Q.; Chen, K.Y.; Li, E.Z.

2013-01-01

Highlights: • Choi–Williams distribution yields excellent time–frequency resolution for discrete signal. • CWD method provides clear time–frequency pictures of EAST and HT-7 fast MHD events. • CWD method has advantages to wavelets transform scalogram and the short-time Fourier transform spectrogram. • We discuss about how to choose the windows and free parameter of CWD method. -- Abstract: The Choi–Williams distribution is applied to the time–frequency analysis of signals describing rapid magneto-hydro-dynamic (MHD) modes and events in tokamak plasmas. A comparison is made with Soft X-ray (SXR) signals as well as Mirnov signal that shows the advantages of the Choi–Williams distribution over both continuous wavelets transform scalogram and the short-time Fourier transform spectrogram. Examples of MHD activities in HT-7 and EAST tokamak are shown, namely the onset of coupling tearing modes, high frequency precursors of sawtooth, and low frequency MHD instabilities in edge localized mode (ELM) free in H mode discharge

Williams Sendromu Olan Bireylerin Ailelerinin Deneyimlerinin ve Karşılaştıkları Güçlüklerin Belirlenmesi

Directory of Open Access Journals (Sweden)

Deniz Tekin Ersan

2016-12-01

Full Text Available Williams Sendromu, belirli bir kromozomda silinme meydana gelmesi ile oluşan nörogelişimsel bir bozukluktur. Görülme sıklığı düşük olan Williams Sendromu ile ilgili yapılmış çalışmalar hem ülkemizde hem de dünyada son derece sınırlıdır. Bu araştırma ile Williams Sendromu olan bireylerin ailelerinin yaşadığı deneyimlerin ve güçlüklerin belirlenmesi amaçlanmaktadır. Araştırmanın modeli nitel araştırma yöntemidir. Araştırmaya beş Williams Sendromu olan bireyin ailesi katılmıştır. Araştırmada veriler, yarı yapılandırılmış görüşme yöntemi ile ve telefon aracılığı ile toplanmıştır. Veriler betimsel analiz ile analiz edilmiştir. Araştırma bulgularına göre; katılımcıların tümünün Williams Sendromu olan bir çocuğa sahip olmayı zor bir deneyim olarak değerlendirdikleri, çocuklarının geleceğine yönelik kaygı taşıdıkları gözlenmiştir. Ailelerin yaşadıkları güçlüklere bakıldığında özellikle çocuklarının davranış problemlerine dair yaşanan güçlükler öne çıkmaktadır. Bunun yanında eğitim ve sağlık alanında uzmanların konu ile ilgili bilgisinin yetersizliği, sahip oldukları olumsuz tutumlar ve aynı zamanda verilen hizmetlerin yetersizliği ile ilgili görüşler öne çıkmaktadır. Ek olarak, kaynakların azlığı ve bilgiye ulaşmanın zorluğuna ilişkin bulgular da elde edilmiştir. Williams Syndrome is a neuro-developmental disorder, which is caused by a deletion in a certain chromosome. Prevalence of Williams Syndrome is low and there is limited number of studies on Williams Syndrome both in our country and abroad. The purpose of this study is to determine experiences and difficulties of parents who have children with Williams Syndrome. It is a qualitative study. Five parents of children with Williams Syndrome were participated in the study. Data collected through semi structured interview via phone calls. Data were analyzed

Williams-Beuren syndrome: pitfalls for diagnosis in limited resources setting

OpenAIRE

Lumaka, Aimé; Lukoo, Rita; Mubungu, Gerrye; Lumbala, Paul; Mbayabo, Gloire; Mupuala, Aimée; Lukusa-Tshilobo, Prosper; Devriendt, Koenraad

2016-01-01

Key Clinical Message Patients with Williams?Beuren Syndrome can be recognized clinically, given the characteristic dysmorphism, intellectual disability, and behavior. We report on a Congolese boy with typical WBS facial characteristics. He suffered meningitis and coma at the age of 2 years then subsequently presented with profound intellectual disability and atypical behavior. The WBS was only made at age 8.2 years and confirmed with FISH testing and microarray?CGH. The present report aims to...

"I Had Made a Mistake": William H. Kilpatrick and the Project Method

Science.gov (United States)

Knoll, Michael

2012-01-01

Background/Context: William H. Kilpatrick is known worldwide as "Mr. Project Method." Despite considerable scholarship by Lawrence A. Cremin, Herbert M. Kliebard, Milton A. Bleeke, John A. Beineke, and others, the origin of Kilpatrick's celebrated paper of 1918 has never been explored in depth and its historical context. Focus of Study:…

Absolutism and Natural Law Argument: William O. Douglas on Freedom of Expression.

Science.gov (United States)

Rodgers, Raymond S.

Noting that United States Supreme Court Justice William O. Douglas has often been characterized as an "absolutist" in terms of First Amendment policy, this paper argues that, in fact, Douglas's policy positions provided for less than absolute freedom to communicate. The paper then reveals, through an anlaysis of 18 of Douglas's opinions,…

William H. Taft High School Project HOLA, 1985-1986. OEA Evaluation Report.

Science.gov (United States)

New York City Board of Education, Brooklyn. Office of Educational Assessment.

Project HOLA at William H. Taft High School (Bronx, New York) assists foreign-born and Puerto Rican-born students to quickly assists foreign- and Puerto Rican-born students to quickly acquire English language skills and an American cultural orientation; to maintain or improve their Spanish language skills and cultural knowledge; and to be…

William H. Taft High School Project HOLA, 1986-1987. OEA Evaluation Report.

Science.gov (United States)

Martinez, Ana L.; And Others

In its fourth year of Title VII funding, Project HOLA at William H. Taft High School served 383 Spanish-speaking students of limited English proficiency from low-income families. The program's goals were to develop English language skills for mainstreaming, to develop an understanding and awareness of American culture and society, to develop…

William Bagley versus Arthur Bestor: Why the Standard Story Is Not True

Science.gov (United States)

Null, J. Wesley

2008-01-01

This essay challenges the conventional understanding of William Bagley and Arthur Bestor, which suggests that they held similar views in curriculum and teacher education. The author thinks this view is completely wrong and provides a radical new interpretation of Bagley and Bestor that uncovers a lost tradition within the field of education.…

Parent and Teacher Perspectives about Problem Behavior in Children with Williams Syndrome

Science.gov (United States)

Klein-Tasman, Bonita P.; Lira, Ernesto N.; Li-Barber, Kirsten T.; Gallo, Frank J.; Brei, Natalie G.

2015-01-01

Problem behavior of 52 children with Williams syndrome ages 6 to 17 years old was examined based on both parent and teacher report. Generally good inter-rater agreement was found. Common areas of problem behavior based both on parent and teacher report included attention problems, anxiety difficulties, repetitive behaviors (e.g., obsessions,…

The Use of Cohesive Markers in Narratives by Children with Williams Syndrome

Science.gov (United States)

Jones, Nancy Elizabeth

2013-01-01

This study examined how children and adolescents with Williams syndrome (WS; ages 8 years, 0 months [8;0]-14;5) used referential devices (determiners and pronouns), tense, and connectives to create cohesion in oral narratives based on a storybook compared to typically developing mentally and chronologically age-matched children. WS children used…

Williams Syndrome Hypersociability: A Neuropsychological Study of the Amygdala and Prefrontal Cortex Hypotheses

Science.gov (United States)

Capitao, Liliana; Sampaio, Adriana; Fernandez, Montse; Sousa, Nuno; Pinheiro, Ana; Goncalves, Oscar F.

2011-01-01

Individuals with Williams syndrome display indiscriminate approach towards strangers. Neuroimaging studies conducted so far have linked this social profile to structural and/or functional abnormalities in WS amygdala and prefrontal cortex. In this study, the neuropsychological hypotheses of amygdala and prefrontal cortex involvement in WS…

‘Wot larx!’: William Morris, Charles Dickens, and Fatherly Feelings

Directory of Open Access Journals (Sweden)

Wendy Parkins

2011-09-01

Full Text Available This essay explores the significance of William Morris’s reading of Dickens for Morris’s articulation of fatherly feelings. Recent scholarship on Victorian fatherhood has begun to overturn the stereotype of the dour, emotionally distant paterfamilias as providing only a partial understanding of forms of middle-class fatherhood and William Morris may serve as an example of a Victorian father whose parenting style eschewed detached authoritarianism, and instead combined nurture, play, and creativity. While Morris referred to Dickens’s works and characters in letters to a range of correspondents, his repeated usage of Joe Gargery’s catchphrase ‘Wot larx!’ (variously spelled occurs exclusively in letters to his wife and daughters, especially the latter. I will consider how the character of Joe Gargery, who combines nurturing tenderness with manly labour, was deployed by Morris to perform a playful and affectionate paternal persona. While Morris’s use of Joe’s catchphrase seems to express a spontaneous overflow of powerful feeling its status as a quotation also works to mark (and mask a disavowal of powerfully ambivalent feelings concerning his own emotional agency as husband and father.

Pre-spill shoreline mapping in Prince William Sound, Alaska

International Nuclear Information System (INIS)

Owens, E.H.; Lamarche, A.; Reimer, P.D.; Marchant, S.O.; O'Brien, D.K.

2003-01-01

A long-term shoreline mapping program has been initiated in Prince William Sound, Alaska, to generate pre-spill data to assist in the planning activities for oil spill response in the area. Low-altitude aerial videotape surveys and video images form the basis for the mapping effort. The coast was initially divided into alongshore segments. The physical shore-zone is relatively homogeneous within each segment. A pre-spill Shoreline Cleanup Assessment Team (SCAT) database, using the ShoreData software, was created based on this initial detailed mapping. The SCAT field teams are therefore equipped with a detailed analysis of the shore-zone character. The same information was also used to develop a separate database for use by planning and response operations groups. The data is entered into the Graphical Resource Database (GRD), and a Geographic Information System (GIS). A simplified characterization of the primary features of each segment is then made available through interpretation of the data. In the event of an oil spill, the SCAT data in the ShoreData files can be combined with field data on shoreline oiling conditions using a second software package called ShoreAccess R which provides summaries of the main parameters required by the planning group. It can also be used as a data storage and management tool. As part of this program, more than 1700 kilometres of shoreline in Prince William Sound have already been mapped. 24 refs., 4 tabs., 5 figs

Instruction, Curriculum and Society: Iterations Based on the Ideas of William Doll

Science.gov (United States)

Varbelow, Sonja

2012-01-01

This paper explores the relationship between society and school from the point of view of chaos theory with the purpose to understand the deficiencies in teacher education programs and to offer suggestions for their improvement. Based on the ideas of the postmodern curriculum theorist William Doll, it examines the paradigm shifts of world views…

Dr William Farr of Shropshire (1807-1883): obstetric mortality and training.

Science.gov (United States)

Dunn, P M

2002-07-01

William Farr, chief statistician to the General Register Office for more than 40 years, was the most significant medical epidemiologist and statistician of the Victorian era. Often working behind the scenes, he helped to bring about many advances in hygiene and public health as well as developing a modern approach to the classification of disease and the collection and analysis of medical information data.

Aortic anomalies in an adolescent with the Williams' elfin facies syndrome

International Nuclear Information System (INIS)

Williams, R.L.; Azouz, E.M.

1984-01-01

An adolescent with classical Williams' syndrome who presented with hypertensive encephalopathy is described. He had the unusual combination of supravalvular aortic stenosis, long segment coarctation of the aorta, aortic hypoplasia and a high bifurcation of the abdominal aorta. Surgical resection of the coarctation was required; however, the patient has remained moderately hypertensive. The aortic anomalies in this syndrome are reviewed and their frequency and importance examined. (orig.)

Mental Health Concerns in Williams Syndrome: Intervention Considerations and Illustrations from Case Examples

Science.gov (United States)

Phillips, Kristin D.; Klein-Tasman, Bonita P.

2009-01-01

The refinement of the Williams syndrome phenotype has frequently included the study of behavioral and temperamental features common to individuals with this disorder. Within this line of research, the importance of evaluating incidence of psychopathology has been increasingly recognized, with studies consistently identifying an increased risk for…

The Development of Metaphorical Language Comprehension in Typical Development and in Williams Syndrome

Science.gov (United States)

Thomas, Michael S. C.; Van Duuren, Mike; Purser, Harry R. M.; Mareschal, Denis; Ansari, Daniel; Karmiloff-Smith, Annette

2010-01-01

The domain of figurative language comprehension was used to probe the developmental relation between language and cognition in typically developing individuals and individuals with Williams syndrome. Extending the work of Vosniadou and Ortony, the emergence of nonliteral similarity and category knowledge was investigated in 117 typically…

Sleep Patterns and Daytime Sleepiness in Adolescents and Young Adults with Williams Syndrome

Science.gov (United States)

Goldman, S. E.; Malow, B. A.; Newman, K. D.; Roof, E.; Dykens, E. M.

2009-01-01

Background: Sleep disorders are common in individuals with neurodevelopmental disorders and may adversely affect daytime functioning. Children with Williams syndrome have been reported to have disturbed sleep; however, no studies have been performed to determine if these problems continue into adolescence and adulthood. Methods: This study…

Ramparts of empire the fortifications of sir william jervois, royal engineer 1821 - 1897

CERN Document Server

Crick, Timothy

2015-01-01

William Jervois was a military engineer who rose to prominence as a result of Lord Palmerston's extensive programme of fortification against a feared French invasion in the middle years of the nineteenth century. Ramparts of Empire is a detailed and engaging study of his life and works.

Cortisol Reactivity and Performance Abilities in Social Situations in Adults with Williams Syndrome

Science.gov (United States)

Lense, Miriam D.; Dykens, Elisabeth M.

2013-01-01

Williams syndrome (WS) is a neurodevelopmental disorder associated with hypersociability and anxiety. However, little is known about how these salient aspects of the phenotype are related or their underlying physiology. We examined cortisol reactivity in WS because cortisol is responsive to psychosocial stress. Compared to typically developing…

Sir William Mitchell (1925-2002)

CERN Multimedia

2002-01-01

Sir William (Bill) Mitchell, former President of the CERN Council, died on 30th October 2002 at the age of 77. Mitchell was professor of Physics at Oxford University from 1978 to 1989, having previously been Professor of Physics, Dean of Science and Deputy Vice-Chancellor at Reading University. From 1985 to 1990 he was Chairman of the UK's Science and Engineering Research Council (SERC), which at the time was the funding agency for the UK's participation in the CERN programme. As Chairman, Mitchell was one of the UK representatives on the CERN Council, and in 1991 he was elected President, a position he held for three years. This was a difficult period for CERN. Financial problems were being faced in many member states, notably in Germany as a result of unification. This led to calls for reductions in the CERN budget and, more significantly, to requests for delays in consderation of future programmes. On the other hand for the future of CERN and the progress of elementary particle physics, it was necessary...

David Owen Williams (1944 - 2006)

CERN Multimedia

2006-01-01

Many people, not only at CERN but also throughout the world, were saddened to learn that their friend and colleague David Williams had passed away in the early hours of Tuesday 24 October. His death came after a year of fighting cancer with all of his usual determination and optimism. Even days before the end he was still welcoming to visitors, and was alert and interested in all their news. Born in 1944, David came to CERN from the University of Cambridge in 1966, with a degree in Physics and Computer Science. Joining what at the time was called the Documents and Data (DD) Division, in the earlier part his career he worked first on software for analysis of bubble chamber photographs, subsequently leading the group that supported experiments with 'hybrids' of bubble chambers and electronic detectors and then the group supporting online computing in experiments. He thus witnessed all of the enormous changes that took place in particle physics as the era of bubble chambers came to an end and the availability ...

William L. Donn 1918-1987

Science.gov (United States)

Gedzelman, Stanley David

William L. Donn, Professor Emeritus of the Department of Earth and Planetary Sciences, City College of New York, and Special Research Scientist at Lamont-Doherty Geological Observatory (LDGO) of Columbia University (Palisades, N.Y.), died at his home on June 30, 1987, at the age of 69. Bill demonstrated expertise in a wide range of fields, with a highly productive and creative research and writing career that included geology, oceanography, climatology, atmospheric physics, and meteorology.Donn was born in Brooklyn, N.Y., on March 2, 1918. At the tender age of 10 years, he demonstrated his love and talent for science by building a telescope with his brother, Bertram. During his undergraduate years at Brooklyn College, he switched his major from astronomy to geology. He was largely selftrained in both meteorology and oceanography, serving as head of the Meteorology Section, U.S. Merchant Marine Academy during World War II . One by-product of these years was the textbook Meteorology—With Marine Applications, first published in 1946. This widely adopted text became a standard for a generation of mariners and college students.

John Dewey, William Wirt and the Gary Schools Plan: A Centennial Reappraisal

Science.gov (United States)

Thorburn, Malcolm

2017-01-01

A century on from the height of John Dewey's educational writings and the reputation of the Gary Schools Plan as a model of progressive education, the paper reappraises two key matters: the relationship between John Dewey and William Wirt, the first superintendent of the Gary Schools in Gary Indiana, and the coherence between John Dewey's…

Item and Error Analysis on Raven's Coloured Progressive Matrices in Williams Syndrome

Science.gov (United States)

Van Herwegen, Jo; Farran, Emily; Annaz, Dagmara

2011-01-01

Raven's Coloured Progressive Matrices (RCPM) is a standardised test that is commonly used to obtain a non-verbal reasoning score for children. As the RCPM involves the matching of a target to a pattern it is also considered to be a visuo-spatial perception task. RCPM is therefore frequently used in studies in Williams Syndrome (WS), in order to…

Expression of an insulin/interleukin-1 receptor antagonist hybrid gene in insulin-producing cell lines (HIT-T15 and NIT-1) confers resistance against interleukin-1-induced nitric oxide production.

Science.gov (United States)

Welsh, N; Bendtzen, K; Welsh, M

1995-01-01

A hybrid gene consisting of the insulin gene enhancer/promoter region, the signal sequence, the insulin B- and C-chains, and the human interleukin-1 receptor antagonist (IL-1ra) gene was constructed. This hybrid gene was transfected together with the pSV2-neo construct into the insulin-producing cell lines HIT-T15 and NIT-1. One of the geneticin-selected clones, HITra2, expressed a 1.4-kb mRNA, which hybridized both to insulin and IL-1ra-cDNA in Northern blot analysis. Three proteins, with the mol wt 23, 17, and 14 kD, were immunoprecipitated with anti-IL-1ra antibodies from [35S]methionine-labeled HITra2 cells. Both at a low and at a high glucose concentration, 4-5 ng of IL-1ra/10(6) cells (ELISA) was released from these cells. On the other hand, a high glucose concentration evoked a three-fold increase in the release of insulin, suggesting that IL-1ra was released constitutively. Measured by nitrite production, transfected HIT, and NIT-1 cells exhibited a more than 10-fold decrease in IL-1 beta sensitivity. Since the conditioned culture media from the HITra2 cells exhibited an anti-IL-1 beta activity of only 0.5 U/ml, and mixed culture of HITra2 cells and isolated rat islets prevented IL-1 beta induced inhibition of insulin release, it is likely that IL-1ra acts locally at the cell surface. It is concluded that expression of a hybrid insulin/IL-1ra gene confers resistance to IL-1 and that this technique may be used to elucidate the role of IL-1 in autoimmune disorders such as insulin-dependent diabetes mellitus. Images PMID:7706480

[William W. Cadbury and canton hospital].

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Liu, Ze-Sheng; Liu, Ze-En

2004-01-01

William W. Cadbury M.D. was born in Philadelphia, USA and graduated from the Medical College of Pennsylvania University. It was nearly 40 years since he arrived in Canton (Guangzhou) in 1909 and left at retirement age. He taught western medicine in Canton Christian College and worked as a medical doctor in Canton Hospital, the oldest western medical hospital in the Orient. He was regarded as a famous foreign doctor and an excellent professor in internal medicine in the Republic of China. He wrote At the point of Lancet: 100 years of Canton Hospital 1835 - 1935, which recorded the achievement made by American missionary doctors, particularly the pioneers such as Peter Parker M.D. and John G. Kerr. M.D. So far the book is still an important reference for the studies on history of western medicine in China and the history of modern medical exchange between China and other countries.

Evaluation of sea otter capture after the Exxon Valdez oil spill, Prince William Sound, Alaska

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Bodkin, James L.; Weltz, F.; Bayha, Keith; Kormendy, Jennifer

1990-01-01

After the T/V Exxon Valdez oil spill into Prince William Sound, the U.S. Fish and Wildlife Service and Exxon Company, U.S.A., began rescuing sea otters (Enhydra lutris). The primary objective of this operation was to capture live, oiled sea otters for cleaning and rehabilitation. Between 30 March and 29 May 1989, 139 live sea otters were captured in the sound and transported to rehabilitation centers in Valdez, Alaska. Within the first 15 days of capture operations, 122 (88%) otters were captured. Most sea otters were captured near Knight, Green, and Evans islands in the western sound. The primary capture method consisted of dipnetting otters out of water and off beaches. While capture rates declined over time, survival of captured otters increased as the interval from spill date to capture date increased. The relative degree of oiling observed for each otter captured declined over time. Declining capture rates led to the use of tangle nets. The evidence suggests the greatest threat to sea otters in Prince William Sound occurred within the first 3 weeks after the spill. Thus, in the future, the authors believe rescue efforts should begin as soon as possible after an oil spill in sea otter habitat. Further, preemptive capture and relocation of sea otters in Prince William Sound may have increased the number of otters that could have survived this event.

The Influence of the Doctor’s Mind Style in Spring and All on William Carlos Williams’s Poetry Creation

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Meiling Fu

2017-05-01

Full Text Available This article intends to investigate the doctor’s mind style on William Carlos Williams in his collection of poems Spring and All. Research shows that Williams’s doctor’s life makes him shape a different view of the world. He always observes something difficult or challenging at first and notices something easy and comfortable at last. This paper concludes that Williams’s doctor’s mind style exerts influence on his creation of poetry both in content and in form.

Charles William Lacaillade. Biologist, Parasitologist, Educator, and Mentor.

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Imperato, Pascal James

2017-02-01

Charles William Lacaillade (1904-1978) was an eminent biologist in the middle decades of the twentieth century. He was born in Lawrence, Massachusetts of parents whose ancestors were French Canadians. His father, also named Charles William Lacaillade, was a dentist who graduated from Tufts University School of Dentistry in 1898. His mother, Elodia Eno, came from a family of very successful businessmen. Lacaillade was the third of six children. His two older brothers, Harold Carleton and Hector Eno, both graduated from the University of Louisville, School of Dentistry, while his younger brother, Lawrence, became a businessman. His sister, Luemma, married Dr. Henry Steadman, a veterinarian, while his youngest sister, Gloria, married a U.S. Army officer, Lieutenant Colonel Victor Anido. Lacaillade received his MS and PhD degrees in biology and zoology from Harvard University. He then became a fellow at The Rockefeller Institute for Medical Research. At both institutions, he studied under some of the most eminent biological scientists of the time. These included Rudolf W. Glaser, George Howard Parker, Theobald Smith, Carl TenBroeck, and William Morton Wheeler. At the Rockefeller Institute, he co-discovered the vector and mode of transmission of Eastern Equine Encephalomyelitis. This discovery, and the research he conducted with Rudolf W. Glaser, quickly established him as an outstanding biological researcher. However, a change in leadership at the Rockefeller Institute resulted in research priorities being given to the disciplines of general physiology, physical chemistry, and nutrition. This shift in the research agenda away from the biological sciences precluded career advancement at the Rockefeller Institute for post-doctoral fellows like Lacaillade. It was the height of the Great Depression, and even biologists with terminal doctoral degrees found it difficult to find positions. In 1935, Lacaillade accepted a position as an assistant in biology at St. John

Bilateral vocal cord paralysis and hypothyroidism as presenting symptoms of Williams-Beuren syndrome: a case report.

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Koren, Ilana; Kessel, Ira; Rotschild, Avi; Cohen-Kerem, Raanan

2015-09-01

Williams-Beuren syndrome is a rare neurodevelopmental disorder caused by deletion of 1.5-1.8Mb genes on chromosome 7q11.23. The syndrome was first described as a triad of supra-valvular aortic stenosis, mental retardation, and distinctive facial features. Our patient was referred due to audible inspiratory stridor when he was seven days old. Following endoscopy he was diagnosed with bilateral vocal cord paralysis and was eventually intubated due to respiratory de-compensation followed by tracheotomy. On further workup he was diagnosed with hypothyroidism. Genetic workup supported the diagnosis of Williams-Beuren syndrome. We report here a case with an unusual clinical presentation. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Longitudinal Trajectories of Intellectual and Adaptive Functioning in Adolescents and Adults with Williams Syndrome

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Fisher, M. H.; Lense, M. D.; Dykens, E. M.

2016-01-01

Background: Williams syndrome (WS) is associated with a distinct cognitive-behavioural phenotype including mild to moderate intellectual disability, visual-spatial deficits, hypersociability, inattention and anxiety. Researchers typically characterise samples of individuals with WS by their intellectual functioning and adaptive behaviour. Because…

33 CFR 167.1703 - In Prince William Sound: Valdez Arm Traffic Separation Scheme.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false In Prince William Sound: Valdez Arm Traffic Separation Scheme. 167.1703 Section 167.1703 Navigation and Navigable Waters COAST GUARD... Description of Traffic Separation Schemes and Precautionary Areas Pacific West Coast § 167.1703 In Prince...

Heterogeneity of Social Approach Behaviour in Williams Syndrome: The Role of Response Inhibition

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Little, Katie; Riby, Deborah M.; Janes, Emily; Clark, Fiona; Fleck, Ruth; Rodgers, Jacqui

2013-01-01

The developmental disorder of Williams syndrome (WS) is associated with an overfriendly personality type, including an increased tendency to approach strangers. This atypical social approach behaviour (SAB) has been linked to two potential theories: the amygdala hypothesis and the frontal lobe hypothesis. The current study aimed to investigate…

Gaze Aversion during Social Style Interactions in Autism Spectrum Disorder and Williams Syndrome

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Doherty-Sneddon, Gwyneth; Whittle, Lisa; Riby, Deborah M.

2013-01-01

During face-to-face interactions typically developing individuals use gaze aversion (GA), away from their questioner, when thinking. GA is also used when individuals with autism (ASD) and Williams syndrome (WS) are thinking during question-answer interactions. We investigated GA strategies during face-to-face social style interactions with…

Pamidronate Rescue Therapy for Hypercalcemia in a Child With Williams Syndrome

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Sami A. Sanjad

2018-05-01

Full Text Available A 15-month-old male infant diagnosed with Williams Syndrome (WS was admitted with severe hypercalcemia and nephrocalcinosis. Intravenous hydration and furosemide failed to yield an appreciable and sustainable fall in serum calcium, while the injection of pamidronate achieved a significant decrease in serum calcium in a short period of time. This bisphosphonate could be considered as a second-line treatment for refractory hypercalcemia in WS.

Shoreline ecology program for Prince William Sound, Alaska, following the Exxon Valdez oil spill. Part 3: Biology

International Nuclear Information System (INIS)

Gilfillan, E.S.; Page, D.S.; Harner, E.J.; Boehm, P.D.

1995-01-01

This study describes the biological results of a comprehensive shoreline ecology program designed to assess ecological recovery in Prince William Sound following the Exxon Valdez oil spill on march 24, 1989. The program is an application of the ''Sediment Quality Triad'' approach, combining chemical, toxicological, and biological measurements. The study was designed so that results could be extrapolated to the entire spill zone in Prince William Sound. The spill affected four major shoreline habitat types in Prince William Sound: pebble/gravel, boulder/cobble, sheltered bedrock, and exposed bedrock. The study design had two components: (1) one-time stratified random sampling at 64 sites representing four habitats and four oiling levels (including unoiled reference sites) and (2) periodic sampling at 12 nonrandomly chosen sites that included some of the most heavily oiled locations in the sound. Biological communities on rock surfaces and in intertidal and shallow subtidal sediments were analyzed for differences resulting from to oiling in each of 16 habitat/tide zone combinations. Statistical methods included univariate analyses of individual species abundances and community parameter variables (total abundance, species richness, and Shannon diversity), and multivariate correspondence analysis of community structure. 58 refs., 13 figs., 9 tabs

The development of perceptual grouping in infants with Williams syndrome

OpenAIRE

Farran, E. K.; Brown, J. H.; Cole, V. L.; Houston-Price, C.; Karmiloff-Smith, A.

2007-01-01

Perceptual grouping by luminance similarity and by proximity was investigated in infants with Williams syndrome (WS) aged between 6 and 36 months (visit 1, N=29). WS infants who were still under 36 months old, 8 months later, repeated the testing procedure (visit 2, N=15). Performance was compared to typically developing (TD) infants aged from 2 to 20 months (N=63). Consistent with the literature, TD participants showed grouping by luminance at the youngest testing age, 2 months. Grouping by ...

William Osler's "The Nervousness of American Women".

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Golden, Richard L

2008-02-01

Almost a century ago, William Osler, the foremost physician of his time, was approached by a leading periodical to write a series of articles on the health of the American woman. Osler, then the Regius Professor of Medicine at Oxford, wrote an essay dealing with the psychological stresses affecting the "new woman" of the early 20th century at varying stages of her development and the "nervousness" that ensued. The article was never published as a result of his belated reservations on the propriety of a professional writing for a lay journal. Osler's thinking frequently reflected the spirit of his Victorian-Edwardian era, although at times he demonstrated advanced and prescient ideas about sexuality, not often the subject of discussion, even in circumspect form, in contemporary nonprofessional literature.

A Mystic in English Literature: William Blake

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Ali Fahri DOĞAN

2015-12-01

Full Text Available Human beings have never been satisfied with this ephemeral world. Perhaps, yearning and desire of rejoining −stemming from the descent from the heaven to the earth− are the emotions felt by the members of both celestial and non-celestial religions. Mysticism, having started with the zeal of people who weren‘t satisfied with this ephemeral world towards the eternal world, aimed at the love of God in the religions where there is a belief of single God. In this article, glancing at the life of a Christian mystic William Blake, we will try to shed light into his mystic thoughts. While studying Blake‘s mystic thoughts, there will be common points with Sufism. Nevertheless, analysis of these common points has been assigned to other studies.

'O' Rose Thou Art Sick': Floral Symbolism in William Blake's Poetry

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Noelia Malla

2014-04-01

Full Text Available The primary aim of this paper is to analyse the symbolic implications of floral imagery in William Blake’s poetry. More specifically, this study explores the process of floral (resignification of William Blake’s Songs of Innocence (1789 and Songs of Experience (1794 as case studies. Since “Without contraries [there] is no progression” (Marriage of Heaven and Hell, plate 3, it can be argued that the Songs represent contrary aspects of the human condition that far from contradicting each other, establish a static contrast of shifting tensions and revaluation of the flower-image not only as a perfect symbol of the “vegetable” life rooted to the Earth but also as a figure longing to be free. In some sense at some level, the poetic-prophetic voice asserts in the Songs of Experience the state of corruption where man has fallen into. Ultimately, this study will explore how the failure to overcome the contrast that is suggested in the Songs will be deepened by the tragedy of Thel, which is symbolized by all unborn forces of life, all sterile seeds as an ultimate means of metaphorical regeneration throughout Poetry which constitutes in itself the Poet Prophet’s own means of transcending through art.

[Diagnosis of a case with Williams-Beuren syndrome with nephrocalcinosis using chromosome microarray analysis].

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Jin, S J; Liu, M; Long, W J; Luo, X P

2016-12-02

Objective: To explore the clinical phenotypes and the genetic cause for a boy with unexplained growth retardation, nephrocalcinosis, auditory anomalies and multi-organ/system developmental disorders. Method: Routine G-banding and chromosome microarray analysis were applied to a child with unexplained growth retardation, nephrocalcinosis, auditory anomalies and multi-organ/system developmental disorders treated in the Department of Pediatrics of Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology in September 2015 and his parents to conduct the chromosomal karyotype analysis and the whole genome scanning. Deleted genes were searched in the Decipher and NCBI databases, and their relationships with the clinical phenotypes were analyzed. Result: A six-month-old boy was refered to us because of unexplained growth retardation and feeding intolerance.The affected child presented with abnormal manifestation such as special face, umbilical hernia, growth retardation, hypothyroidism, congenital heart disease, right ear sensorineural deafness, hypercalcemia and nephrocalcinosis. The child's karyotype was 46, XY, 16qh + , and his parents' karyotypes were normal. Chromosome microarray analysis revealed a 1 436 kb deletion on the 7q11.23(72701098_74136633) region of the child. This region included 23 protein-coding genes, which were reported to be corresponding to Williams-Beuren syndrome and its certain clinical phenotypes. His parents' results of chromosome microarray analysis were normal. Conclusion: A boy with characteristic manifestation of Williams-Beuren syndrome and rare nephrocalcinosis was diagnosed using chromosome microarray analysis. The deletion on the 7q11.23 might be related to the clinical phenotypes of Williams-Beuren syndrome, yet further studies are needed.

Attention Bias to Emotional Faces Varies by IQ and Anxiety in Williams Syndrome

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McGrath, Lauren M.; Oates, Joyce M.; Dai, Yael G.; Dodd, Helen F.; Waxler, Jessica; Clements, Caitlin C.; Weill, Sydney; Hoffnagle, Alison; Anderson, Erin; MacRae, Rebecca; Mullett, Jennifer; McDougle, Christopher J.; Pober, Barbara R.; Smoller, Jordan W.

2016-01-01

Individuals with Williams syndrome (WS) often experience significant anxiety. A promising approach to anxiety intervention has emerged from cognitive studies of attention bias to threat. To investigate the utility of this intervention in WS, this study examined attention bias to happy and angry faces in individuals with WS (N = 46). Results showed…

Brookhaven Lab physicist William Willis wins the 2003 W.K.H. Panofsky prize

CERN Multimedia

2003-01-01

William Willis, a senior physicist Brookhaven National Laboratory, has won the American Physical Society's 2003 W.K.H. Panofsky Prize in Experimental Particle Physics. He received the prize, which consists of $5,000 and a certificate citing his contributions to physics, at the APS meeting in Philadelphia on April 6 (1 page).

Referential Communication Skills of Children with Williams Syndrome: Understanding when Messages Are Not Adequate

Science.gov (United States)

John, Angela E.; Rowe, Melissa L.; Mervis, Carolyn B.

2009-01-01

Although children with Williams syndrome have relatively good structural language and concrete vocabulary abilities, they have difficulty with pragmatic aspects of language. To investigate the impact of pragmatic difficulties on listener-role referential communication, we administered a picture placement task designed to measure ability to…

Periodic Reactions: The Early Works of William C. Bray and Alfred J. Lotka

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Cervellati, Rinaldo; Greco, Emanuela

2017-01-01

Oscillating chemical reactions in the homogeneous phase have been studied intensively only since the mid-1960s, but they were known since 1920, having as forerunners the chemist William C. Bray and an "atypical" chemist Alfred J. Lotka. This contribution is the result of a careful reading of their literature and patient research into…

Performance on the Kaufman Brief Intelligence Test-2 by Children with Williams Syndrome

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Pitts, C. Holley; Mervis, Carolyn B.

2016-01-01

We describe the performance of 292 4- to 17-year-olds with Williams syndrome (WS) on the Kaufman Brief Intelligence Test-2 (KBIT-2; Kaufman & Kaufman, 2004). Mean IQ Composite, Verbal standard score (SS), and Nonverbal SS were in the borderline range relative to the general population, with variability similar to the general population.…

Atypical Verbal Communication Pattern According to Others' Attention in Children with Williams Syndrome

Science.gov (United States)

Asada, Kosuke; Tomiwa, Kiyotaka; Okada, Masako; Itakura, Shoji

2010-01-01

Children with Williams syndrome (WS) have been reported to often face problems in daily communication and to have deficits in their pragmatic language abilities. To test this hypothesis, we examined whether children with WS could modify their verbal communication according to others' attention in order to share what they did. The children with WS…

Cognitive, Linguistic and Adaptive Functioning in Williams Syndrome: Trajectories from Early to Middle Adulthood

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Howlin, Patricia; Elison, Sarah; Udwin, Orlee; Stinton, Christopher

2010-01-01

Background: Little is known about trajectories of cognitive functioning as individuals with Williams syndrome (WS) move though adulthood. Method: The present study investigated cognitive, linguistic and adaptive functioning in adults with WS aged 19-55 years, using both cross-sectional and longitudinal approaches. Results: Data from the…

William Crabtree and the date of Easter

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Sellers, D.

2014-04-01

A previously unknown treatise by William Crabtree (c.1603-c.1644) has recently been unearthed in the Lancashire Record Office. The treatise, in manuscript form and written in 1640, deals with the controversy over the long-term impact of the Julian Calendar - then in use in England - upon the ecclesiastical dating of Easter. By Crabtree's time, the timing of the Easter celebration in England was often several weeks adrift of the intentions of the early Church Fathers. The Gregorian Calendar, which Roman Catholic countries had adopted as long ago as 1582 in order to resolve the problem, was still vehemently resisted by the English state. This is possibly the only surviving manuscript in Crabtree's own hand. In it, he displays noteworthy dispassionate objectivity as he outlines the astronomical basis for the Easter date and explains why it has gone awry.

William Allen Miller (1817-70): a distinguished scientist re-discovered.

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Ashley-Miller, Michael

2008-11-01

Dr William Allen Miller developed an early interest in science and astronomy at secondary school. Although qualifying in medicine, he pursued a career in Chemistry at King's College, London. A particular interest in spectrum analysis led to a collaboration with Dr Huggins in examining the spectra of stars. For this work they each received the Gold Medal of the Royal Astronomical Society. His subsequent work at King's College, the Royal Society, the Courts of Law and for various Government enterprises earned him an outstanding scientific and advisory reputation.

Pulmonary Arterial Stent Implantation in an Adult with Williams Syndrome

International Nuclear Information System (INIS)

Reesink, Herre J.; Henneman, Onno D. F.; Delden, Otto M. van; Biervliet, Jules D.; Kloek, Jaap J.; Reekers, Jim A.; Bresser, Paul

2007-01-01

We report a 38-year-old patient who presented with pulmonary hypertension and right ventricular dysfunction due to pulmonary artery stenoses as a manifestation of Williams syndrome, mimicking chronic thromboembolic pulmonary hypertension. The patient was treated with balloon angioplasty and stent implantation. Short-term follow-up showed a good clinical result with excellent patency of the stents but early restenosis of the segments in which only balloon angioplasty was performed. These stenoses were subsequently also treated successfully by stent implantation. Stent patency was observed 3 years after the first procedure

Dr. William O. Coffee and his absorption cure for cataract.

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Ferry, A P

1989-08-01

Dr. William O. Coffee was an ophthalmologist who conducted an office and mail-order practice in the Midwest from the 1880s until 1927. His main stock in trade was a self-discovered absorption cure for a variety of ocular diseases, with particular emphasis on the medical cure of cataracts. Dr. Coffee's career was a checkered one, marked by dubious credentials, exuberant self-promotion, unlikely and exaggerated claims of medical successes, plagiarism, and rejection by the medical "establishment." Certain parallels may be drawn between his activities and some currently observed practices in ophthalmology.

[Sir William Richard Gowers: author of the "bible of neurology"].

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Hirose, Genjiro

2014-11-01

William Richard Gowers is one of the great pioneers in neurology and the author of the well-known neurology textbook, "A Manual of Diseases of the Nervous System." His concepts of neurology are based on meticulously and carefully accumulated knowledge of history, observations, and neurological examinations of patients with various neurological diseases. He is not only a great neurologist but also a great teacher who loves teaching students and physicians through well-prepared lectures. We can glean the essence of the field of neurology through his life story and numerous writings concerning neurological diseases.

A gestalt approach to the science fiction novels of William Gibson

OpenAIRE

McFarlane, Anna M.

2015-01-01

Gestalt psychologists Kurt Koffka and Wolfgang Köhler argue that human perception relies on a form, or gestalt, into which perceptions are assimilated. Gestalt theory has been applied to the visual arts by Rudolf Arnheim and to literature by Wolfgang Iser. My original contribution to knowledge is to use gestalt theory to perform literary criticism, an approach that highlights the importance of perception in William Gibson’s novels and the impact of this emphasis on posthumanism and science fi...

Brief Report: Major Depressive Disorder with Psychotic Features in Williams Syndrome--A Case Series

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Valdes, Francisca; Keary, Christopher J.; Mullett, Jennifer E.; Palumbo, Michelle L.; Waxler, Jessica L.; Pober, Barbara R.; McDougle, Christopher J.

2018-01-01

Descriptions of individuals with Williams syndrome (WS) and co-morbid major depressive disorder (MDD) with psychotic features have not appeared in the literature. In addition to reviewing previous reports of psychotic symptoms in persons with WS, this paper introduces clinical histories and therapeutic management strategies for three previously…

Brief Report: Exploring the Relationship between Sensory Processing and Repetitive Behaviours in Williams Syndrome

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Riby, Deborah M.; Janes, Emily; Rodgers, Jacqui

2013-01-01

This study explored the relationship between sensory processing abnormalities and repetitive behaviours in children with Williams Syndrome (WS; n = 21). This is a novel investigation bringing together two clinical phenomena for the first time in this neuro-developmental disorder. Parents completed the Sensory Profile (Short Form; Dunn in The…

William Blake’s Milton a Poem as a conversion narrative in the Behmenist tradition

DEFF Research Database (Denmark)

Jessen, Elisabeth Engell

2014-01-01

The term ‘conversion narrative’ lacks proper definition and can be understood more broadly than is often the case, underlining its fictive nature. I show this by reading William Blake’s Milton a Poem as a conversion narrative, exploring how Blake weaves a wider discourse of conversion around...

Surgical repair of supravalvular aortic stenosis in children with williams syndrome: a 30-year experience.

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Fricke, Tyson A; d'Udekem, Yves; Brizard, Christian P; Wheaton, Gavin; Weintraub, Robert G; Konstantinov, Igor E

2015-04-01

Williams syndrome is an uncommon genetic disorder associated with supravalvular aortic stenosis (SVAS) in childhood. We reviewed outcomes of children with Williams syndrome who underwent repair of SVAS during a 30-year period at a single institution. Between 1982 and 2012, 28 patients with Williams syndrome were operated on for SVAS. Mean age at operation was 5.2 years (range, 3 months to 13 years), and mean weight at operation was 18.6 kg (range, 4.1 to 72.4 kg). Associated cardiac lesions in 11 patients (39.3%) were repaired at the time of the SVAS repair. The most common associated cardiac lesion was main pulmonary artery stenosis (8 of 28 [28%]). A 3-patch repair was performed in 10 patients, a Doty repair in 17, and a McGoon repair in 1 (3.6%). There were no early deaths. Follow-up was 96% complete (27 of 28). Overall mean follow-up was 11.2 years (range, 1 month to 27.3 years). Mean follow-up was 5 years (range, 1 month to 14.3 years) for the 3-patch repair patients and 14.7 years (range, 6 weeks to 27 years) for the Doty repair patients. Of the 17 Doty patients, there were 4 (24%) late deaths, occurring at 6 weeks, 3.5 years, 4 years, and 16 years after the initial operation. There were no late deaths in the 3-patch repair patients. Overall survival was 86% at 5, 10, and 15 years after repair. Survival was 82% at 5, 10 and 15 years for the Doty repair patients. Overall, 6 of 27 patients (22%) patients required late reoperation at a mean of 11.2 years (range, 3.6 to 23 years). No 3-patch repair patients required reoperation. Overall freedom from reoperation was 91% at 5 years and 73% at 10 and 15 years. Freedom from reoperation for the Doty repair patients was 93% at 5 years and 71% at 10 and 15 years. Surgical repair of SVAS in children Williams syndrome has excellent early results. However, significant late mortality and morbidity warrants close follow-up. Copyright © 2015 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights

Syntax in Spanish-speaking children with Williams syndrome.

Science.gov (United States)

Benítez-Burraco, Antonio; Garayzábal, Elena; Cuetos, Fernando

2016-01-01

The syntactic skills of Spanish-speaking children with Williams syndrome (WS) were assessed in different areas (phrase structure, recursion, and bound anaphora). Children were compared to typically-developing peers matched either in chronological age (CA-TD) or in verbal age (VA-TD). In all tasks children with WS performed significantly worse than CA-TD children, but similarly to VA-TD children. However, significant differences were observed in specific domains, particularly regarding sentences with cross-serial dependencies. At the same time, children with WS were less sensitive to syntactic constraints and exhibited a poorer knowledge of some functional words (specifically, of nonreflexive pronouns). A processing bottleneck or a computational constraint may account for this outcome. Copyright © 2016 Elsevier Inc. All rights reserved.

The other Dr Hooker: William Dawson Hooker (1816-40).

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Lambert, Harold

2011-11-01

William Hooker and his son Joseph were famous as botanists and as the creators of the Royal Botanic Gardens in Kew. Joseph was famous also as the friend and mentor of Charles Darwin. But there was another brother, a little older than Joseph, also a doctor and naturalist. He went to Jamaica in the interests of his health and soon died there of yellow fever. His life was short and tragic with a medical conundrum at its end but its story also illustrates many of the beliefs and concerns that preoccupied doctors in this early Victorian era. It also illustrates the close relationship between medicine and botany that prevailed then.

Developmental Trajectories of Structural and Pragmatic Language Skills in School-Aged Children with Williams Syndrome

Science.gov (United States)

Van Den Heuvel, E.; Manders, E.; Swillen, A.; Zink, I.

2016-01-01

Background: This study aimed to compare developmental courses of structural and pragmatic language skills in school-aged children with Williams syndrome (WS) and children with idiopathic intellectual disability (IID). Comparison of these language trajectories could highlight syndrome-specific developmental features. Method: Twelve monolingual…

Exegesis seeking appropriation; appropriation seeking exegesis: Re-reading 2 Samuel 13:1−22 in search of redemptive masculinities

Directory of Open Access Journals (Sweden)

Gerald West

2013-09-01

Full Text Available Exegesis in the traditional sense is concerned with generating as much (scientific detail about a biblical text as possible. Whilst the two primary modes of biblical exegesis � socio-historical and literary-semiotic � do this differently, they share a common concern for the detail of the text as an ancient artefact. Critical distance is a key concept here, with the exegetes bracketing (for a moment their own contexts and concerns. However, such bracketing is impossible to sustain, and so the exegetes� interests (shaped by their contexts and concerns �leak� into the act of exegesis. Most exegetes today recognise this leakage, and whilst some still view such leakage as contaminating the exegesis, others, including the tradition of African biblical scholarship, actively identify the contextual concerns they bring to the task of exegesis, both respecting the detail of the text and desiring to be accountable to their contexts in which the Bible is a significant text. This article explored some of the dimensions of forms of exegesis that actively seek appropriation, using 2 Samuel 13:1�22 as an example. In this case, the article analysed the contextual shift from a focus on women as the victims of sexual violence to an emerging emphasis on masculinities. Reading the same text from these different contextual concerns �activates� particular details of the text, and so both draw on different elements of the text and thus guides the gaze of exegesis.

Recognition of Emotional and Nonemotional Facial Expressions: A Comparison between Williams Syndrome and Autism

Science.gov (United States)

Lacroix, Agnes; Guidetti, Michele; Roge, Bernadette; Reilly, Judy

2009-01-01

The aim of our study was to compare two neurodevelopmental disorders (Williams syndrome and autism) in terms of the ability to recognize emotional and nonemotional facial expressions. The comparison of these two disorders is particularly relevant to the investigation of face processing and should contribute to a better understanding of social…

False Belief Attribution in Children with Williams Syndrome: The Answer Is in The Emotion

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Campos, R.; Martínez-Castilla, P.; Sotillo, M.

2017-01-01

Background: Individuals with Williams syndrome (WS) show difficulties in attributing false beliefs, whereas they are better at attributing emotions. This study examines whether being asked about the emotion linked to a false belief, instead of explicitly about the belief, facilitates performance on theory of mind (ToM) tasks. Method: Thirty…

Prosodic Abilities in Spanish and English Children with Williams Syndrome: A Cross-Linguistic Study

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Martinez-Castilla, Pastora; Stojanovik, Vesna; Setter, Jane; Sotillo, Maria

2012-01-01

The aim of this study was to compare the prosodic profiles of English- and Spanish-speaking children with Williams syndrome (WS), examining cross-linguistic differences. Two groups of children with WS, English and Spanish, of similar chronological and nonverbal mental age, were compared on performance in expressive and receptive prosodic tasks…

Developments in fiber-positioning technology for the WEAVE instrument at the William Herschel Telescope

NARCIS (Netherlands)

Schallig, Ellen; Lewis, Ian J.; Gilbert, James; Dalton, Gavin; Brock, Matthew; Abrams, Don Carlos; Middleton, Kevin; Aguerri, J. Alfonso L.; Bonifacio, Piercarlo; Carrasco, Esperanza; Trager, Scott C.; Vallenari, Antonella

2016-01-01

WEAVE is the next-generation wide-field optical spectroscopy facility for the William Herschel Telescope (WHT) on La Palma in the Canary Islands, Spain. It is a multi-object "pick-and-place" fibre-fed spectrograph with a 1000 fibre multiplex behind a new dedicated 2° prime focus corrector. The WEAVE

Readings on the Comedies (William Shakespeare). The Greenhaven Press Literary Companion to British Literature.

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Swisher, Clarice, Ed.

Intended as an accessible resource for students researching William Shakespeare's (1564-1616) "Comedies," this collection of essays about the great playwright contains an in-depth biography and writings taken from a wide variety of sources. The essays are edited to accommodate the reading and comprehension levels of young adults; each…

Effectiveness of commercial microbial products in enhancing oil degradation in Prince William Sound field plots

International Nuclear Information System (INIS)

Venosa, A.D.; Haines, J.R.; Allen, D.M.

1991-01-01

In the spring of 1990, previously reported laboratory experiments were conducted on 10 commercial microbial products to test for enhanced biodegradation of weathered crude oil from the Exxon Valdez oil spill. The laboratory tests measured the rate and extent of oil degradation in closed flasks. Weathered oil from the beaches in Alaska and seawater from Prince William Sound were used in the tests. Two of the 10 products were found to provide significantly greater alkane degradation than flasks supplemented with mineral nutrients alone. These two products were selected for further testing on a beach in Prince William Sound. A randomized complete block experiment was designed to compare the effectiveness of these two products in enhancing oil degradation compared to simple fertilizer alone. Four small plots consisting of a no nutrient control, a mineral nutrient plot, and two plots receiving mineral nutrients plus the two products, were laid out on a contaminated beach. These four plots comprised a 'block' of treatments, and this block was replicated four times on the same beach. Triplicate samples of beach sediment were collected at four equally spaced time intervals and analyzed for oil residue weight and alkane hydrocarbon profile changes with time. The objective was to determine if either of the two commercial microbiological products was able to enhance bioremediation of an oil-contaminated beach in Prince William Sound to an extent greater than that achievable by simple fertilizer application. Results indicated no significant differences among the four treatments in the 27-day period of the experiment

The Dance of the Dead Rhino: William Kentridge’s Magic Flute

OpenAIRE

Guarracino, Serena

2010-01-01

The article offers a reading of the staging of The Magic Flute by visual artist William Kentridge, focusing on his introduction of the rhino in the visual landscape of the opera as symbol for the silenced subject of violence. Operatic tradition has always been concerned with the staging of death, in particular with the death of its female protagonists, and recent scholarship has highlighted the complicity of the genre with the ideology of Western patriarchy and colonial violence. In this ligh...

Ian D. Copestake, The Ethics of William Carlos Williams’s Poetry.

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Aristotle University of Greece

2011-09-01

Full Text Available Ian D. Copestake’s monograph on William Carlos Williams’s poetry offers a well-informed and well-documented insight into the connection between Williams’s writing with Unitarianism and Emersonian thinking. In this very well-written and accessible book, the reader gets introduced to a number of poems in addition to excerpts from Williams’s essays, letters and autobiography which facilitate the understanding and appreciation of the poet’s attempt to promote “independent thought and action” (5....

The Unrequited Love as Reflected in William Blake's “Love's Secret”

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Risthania, Olivia Fergie

2014-01-01

The purpose of this final academic paper is to describe the love story which tells sadness in William Blake's “Love's Secret”. The writer adopts Erich Fromm's theory of unrequited love from The Art of Loving. This final academic paper concerns intrinsic and extrinsic side of the poem. In the intrinsic side, the writer discusses about the existing diction and figurative language such as denotation and connotation and imagery to understand the true meaning of the poem. The extrinsic side, the w...

Welcome Donald Trump, Baltics! The presidency to endure? / Mark Hertling, William E. Pomeranz ; intervjueeris Linas Jegelevicius

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Hertling, Mark

2017-01-01

USA Euroopa vägede endine ülem kindralleitnant Mark Hertlingi ja Kennani Instituudi asedirektor William E. Pomeranz analüüsivad Ameerika Ühendriikide uue presidendi Tonald Trumpi ametisseasumise võimalikku mõju Balti riikide julgeolekule

Significance of calculated cluster conformations of benzene: comment on a publication by D. E. Williams

NARCIS (Netherlands)

van de Waal, B.W.

1981-01-01

Results of potential-energy minimization, applied to clusters of benzene molecules, have been reported recently by Williams [Acta Cryst. (1980), A36, 715-723]. Two stable tridecamer clusters were found and compared with a 13-molecule fragment from crystalline orthorhombic benzene. In this comment

William Graham Brooke (1835-1907): Advocate of Girls' Superior Schooling in Nineteenth-Century Ireland

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McCormack, Christopher F.

2015-01-01

This paper examines the role of William Graham Brooke as advocate of women's higher education and access to university. His work as advocate is considered against the religious, political, social and economic backdrop of late nineteenth century Ireland. A barrister, as Clerk in the Lord Chancellor's office, he was centrally involved in the…

‘His father’s voice’: Phonographs and Heredity in the Fiction of Samuel Butler

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Will Abberley

2014-05-01

Full Text Available The article explores the interaction between concepts of heredity and technologies of voice recording and reproduction in the late-Victorian imagination through the example of Samuel Butler. Butler’s writing on evolutionary topics frequently conceptualized heredity as a record of ancestral voices echoing through their descendants. His Lamarckian view of evolution caused him to present heredity as analogous to the phonograph, recording the experiences of individuals, storing them in the germ plasm and reproducing them in the offspring. Theorists of hereditary memory such as Ewald Hering described it as a form of vibration and inscription, emphasizing its parallels with phonography. At the same time, language and the physical voice seemed equally haunted for Butler, resonating with the thoughts, feelings, and urges of past generations. I pursue these themes through a close reading of his posthumously published novel The Way of All Flesh' (1903. Butler makes an interesting case study for this subject since his ideas about the inheritance of ancestral voices were inseparable from his complex personal relations with his family. His efforts to escape the influence of his parents were bound up with the notion of escaping the habitual ‘grooves’ in which they lived, thought, and spoke. Such escape sometimes seems impossible in Butler’s vision, with long-term heredity and immediate social convention rendering people echoes of their predecessors. However, the life experience of the individual offered possibilities for breaking with the voices of the past, etching new grooves of habit and redirecting old ones. Further, heredity in Butler’s vision was not a single, commanding voice but a cacophony of competing voices screaming to be heard. In this sense, what seemed like rebellion against the voice of one’s ancestor might turn out to be obedience towards another one. Butler conceived of intellectual influence in the same way, placing thinkers and

Théologie et ecclésiologie chez William Laud (1573-1645, archevêque de Cantorbéry Theology and Ecclesiology in the Thought of William Laud (1573-1645, Archbishop of Canterbury

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Pierre Lurbe

2009-05-01

Full Text Available This article argues that William Laud’s theology and ecclesiology are strongly interrelated. A theologian who gave pride of place to sacramental life, and whose forceful rejection of predestination made him close to Arminianism, Laud followed in the footsteps of Saint Cyprian in upholding episcopacy as the proper form of government for the Church.

Neurosurgeon as innovator: William V. Cone (1897-1959).

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Preul, M C; Stratford, J; Bertrand, G; Feindel, W

1993-10-01

Neurosurgeons are well known for being productive researchers and innovators. Few, however, have possessed the prolific ingenuity of William Cone. In 1934, he and William Penfield were cofounders of the Montreal Neurological Institute where, until 1959, he filled the twin roles of neurosurgeon-in-chief and neuropathologist. Because he did not find writing easy, many of his technical inventions and refinements remained unpublished. His numerous innovations included the extensive use of twist-drill technique for biopsy, drainage for subdural hematoma and cerebral abscess, and ventriculography. In the mid-1940's, he developed power tools driven by nitrogen that led to the modern, universally used air-driven tool systems. He had a special interest in the treatment of spinal dysfunction, for which he invented the Cone-Barton skull-traction tongs along with the Cone spinal operating table. He also devised operative procedures for vertebral fracture-dislocation and craniospinal anomalies. For the maintenance of muscle tone in the paralyzed bladder, he constructed a tidal drainage system. He introduced and popularized ventriculoperitoneal shunting techniques and carried out some of the earliest experimental trails to treat brain infections with sulphonamide and antibiotic drugs. He designed his own set of surgical suction devices, bone rongeurs, and a personal suction "air-conditioning" system for each surgeon. He had a keen early interest in intracranial tumors, and also demonstrated on monkeys how subdural mass lesions caused pupillary dilation and mesial temporal lobe damage due to cerebral compression. His work for the military during World War II on effects of altitude on brain pressure remained classified for many years. The first clipping and excision of an intracranial aneurysm is attributed to Cone. Although Penfield was known as "the Chief," Cone was referred to as "the Boss." His fervent dedication to provide total care to his patients was expressed in round

National Program for Inspection of Non-Federal Dams. Williams Pond Dam (CT 00551), Thames River Basin, Lebanon, Connecticut. Phase I Inspection Program.

Science.gov (United States)

1978-10-01

GRA&I UnTucea B WILLIAMS POND DAM ~~1Z~ CT 00551 _ Distribution/ Availabilit Y Codes Avail and/or Dis~tj pecialS RIVER BASIN ~lIILEBANON, COXNNECTICUT...Inspection Report. Alternatives to these recommendations r 1 would include reducing the Williams Pond water levels during expected periods of intense storm...Materials Branch Engi’neering Division FRED J. VNS. Jr., Member Chief, De ’ggn Branch Engineering Division SAUL COOPER, -r Chief, Water Control Branch

Wilsonian visions of a new world order in concrete terms : the case of William C. Bullitt / Alexander Sedlmaier

Index Scriptorium Estoniae

Sedlmaier, Alexander

2003-01-01

President Wilsoni internatsionalismi ideede pooldajast, vasakpoolse poliitika kriitikust pärast I maailmasõda Ameerika - Saksamaa suhete taustal, ajakirjanikust ja diplomaadist William C. Bullitt'ist (1891-1967)

William Horsley: Music Master at Miss Black's Boarding-School for Young Ladies, 1828-1840

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Woodall, Susan

2009-01-01

William Horsley (1775-1858) was active in London from the late 1790s. A founder member of the Philharmonic Society, Horsley was at the heart of the musical establishment, working as a composer, organist, commentator and teacher. His teaching career spanned over 50 years, during which time he took private pupils, trained choristers and organists…

William H. Taft High School Project HOLA 1984-1985. O.E.A. Evaluation Report.

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New York City Board of Education, Brooklyn. Office of Educational Assessment.

In 1984-85, Project HOLA was in its second year of funding at William H. Taft High School in the Bronx, New York. HOLA serves Spanish-speaking students of limited English proficiency (LEP). Project goals include speedy acquisition of English skills, orientation to life in America, maintenance and improvement of Spanish skills and cultural…

Address by William J. Bennett, United States Secretary of Education. (Harvard University, Cambridge, Massachusetts).

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Bennett, William J.

The extent to which U.S. colleges and universities contribute to the fulfillment of students' lives is discussed by Secretary of Education William Bennett in an address to Harvard University. Secretary Bennett's observations are based on his experiences as a law student, freshman proctor, and tutor at Harvard University, as well as his subsequent…

Williams-Beuren syndrome: pitfalls for diagnosis in limited resources setting.

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Lumaka, Aimé; Lukoo, Rita; Mubungu, Gerrye; Lumbala, Paul; Mbayabo, Gloire; Mupuala, Aimée; Tshilobo, Prosper Lukusa; Devriendt, Koenraad

2016-03-01

Patients with Williams-Beuren Syndrome can be recognized clinically, given the characteristic dysmorphism, intellectual disability, and behavior. We report on a Congolese boy with typical WBS facial characteristics. He suffered meningitis and coma at the age of 2 years then subsequently presented with profound intellectual disability and atypical behavior. The WBS was only made at age 8.2 years and confirmed with FISH testing and microarray-CGH. The present report aims to warn clinicians that infections may associate and/or modify a genetic disease as this may be observed in developing countries given the prevalence of infectious diseases.

Kamahouse'i asutamise pöörane lugu / Kadri Jakobson ; vahendanud Ursula Zimmermann ; kommenteerinud William Piper

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Jakobson, Kadri, 1970-

2012-01-01

Kunsti ja äri ühendamisest: kobarärist Koplis, kuhu kuuluvad Kamahouse Galerii, Eero Kotli Tellisstuudio, Unique Home Art, William Piper konsultatsioonibüroo, Meeskonnakoolituse ja Arenduse OÜ, kauplus-stuudio Õnneküpsis, kohvik Kamahouse'i Köök

Religious Experience and its Essentialism in William James and Ghazzali’s Views

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Ahmad Ebadi

2016-03-01

Full Text Available Abstract Religious experience is an approach to which Western thinkers are considered pioneers among whom Schleiermacher is the most prominent. "The essentialism of religious experience" is one of the several approaches that have been adopted in the case of religious experience. Accordingly, the religion that has sides and various dimensions has been reduced to a religious experience and the religious experience is introduced as the essence of religion. What is presented in this article is a comparative study of the essence of religious experience from the perspective of William James and Ghazzāli. Although mystical experience has a different structure form the religious experience and Ghazali as well as other Muslim philosophers and mystics paid more attention to the way of mystical experience, in the works of Ghazali there are also a traces of religious experience and hence, they are adaptable to some aspects of religious experience offered by William James. William James defines the religion “as the feelings, acts, and experiences that can occur for every individual in their solitudes and he believes that feeling is the essential pillar of religion and inherently reinforces it”. Religious experience is the essence of religion and it means that-the truth of the faith is the same as feelings and emotions that emerge from rational reflections on concrete reality as such, and other spiritual, transcendental, mystical and psychological actions are the consequences of these experiences. On the other hand, in the Muslim world, Al-Ghazzali believes that: The ultimate and holy aim of religion is the perception and experience of ultimate truth that can be achieved through good deeds, worship, asceticism and piety. This article tries to find similarities and differences in essence of religious experience of the two thinkers, because it is only in the theory of the essentialism of religious experience that the similarities and differences of

Seguridad social, empleo y propiedad privada en William Beveridge

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Claudio Llanos Reyes

2013-09-01

Full Text Available This article aims to approach the economic and political notions of William Beveridge, which proposed the construction of the British Welfare State immediately after WWII. A form of State which sought to overcome the crisis of capitalism by proposing control over the system. We attempt to demonstrate the relation that should exist, according to Beveridge, the "father" of this model of capitalist State, between the development of a social security system, employment, and the situation of private property, while simultaneously pointing out the specifics and complexity of his ideas in the relation observed between full occupation and private property as basic elements for the construction of a Social Security system.

Viewing Social Scenes: A Visual Scan-Path Study Comparing Fragile X Syndrome and Williams Syndrome

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Williams, Tracey A.; Porter, Melanie A.; Langdon, Robyn

2013-01-01

Fragile X syndrome (FXS) and Williams syndrome (WS) are both genetic disorders which present with similar cognitive-behavioral problems, but distinct social phenotypes. Despite these social differences both syndromes display poor social relations which may result from abnormal social processing. This study aimed to manipulate the location of…