Optimal sampling strategies for detecting zoonotic disease epidemics.

Science.gov (United States)

Ferguson, Jake M; Langebrake, Jessica B; Cannataro, Vincent L; Garcia, Andres J; Hamman, Elizabeth A; Martcheva, Maia; Osenberg, Craig W

2014-06-01

The early detection of disease epidemics reduces the chance of successful introductions into new locales, minimizes the number of infections, and reduces the financial impact. We develop a framework to determine the optimal sampling strategy for disease detection in zoonotic host-vector epidemiological systems when a disease goes from below detectable levels to an epidemic. We find that if the time of disease introduction is known then the optimal sampling strategy can switch abruptly between sampling only from the vector population to sampling only from the host population. We also construct time-independent optimal sampling strategies when conducting periodic sampling that can involve sampling both the host and the vector populations simultaneously. Both time-dependent and -independent solutions can be useful for sampling design, depending on whether the time of introduction of the disease is known or not. We illustrate the approach with West Nile virus, a globally-spreading zoonotic arbovirus. Though our analytical results are based on a linearization of the dynamical systems, the sampling rules appear robust over a wide range of parameter space when compared to nonlinear simulation models. Our results suggest some simple rules that can be used by practitioners when developing surveillance programs. These rules require knowledge of transition rates between epidemiological compartments, which population was initially infected, and of the cost per sample for serological tests.

Strategies for self-management support by patients with stroke: integrative review

Directory of Open Access Journals (Sweden)

Huana Carolina Cândido Morais

2015-02-01

Full Text Available OBJECTIVE To analyze strategies for self-management support by patients with stroke in the light of the methodology of the five A's (ask, advice, assess, assist and arrange. METHODS Integrative review conducted at the following databases CINAHL, SCOPUS, PubMed, Cochrane and LILACS. RESULTS A total of 43 studies published between 2000 and 2013 comprised the study sample. All proposed actions in the five A's methodology and others were included. We highlight the Assist and Arrange, in which we added actions, especially with regard to the use of technological resources and joint monitoring between patients, families and professionals. No study included all five A's, which suggests that the actions of supported self-management are developed in a fragmented way. CONCLUSION The use of five A's strategy provides guidelines for better management of patients with stroke with lower cost and higher effectiveness.

Nutritional strategies to support concurrent training.

Science.gov (United States)

Perez-Schindler, Joaquin; Hamilton, D Lee; Moore, Daniel R; Baar, Keith; Philp, Andrew

2015-01-01

Concurrent training (the combination of endurance exercise to resistance training) is a common practice for athletes looking to maximise strength and endurance. Over 20 years ago, it was first observed that performing endurance exercise after resistance exercise could have detrimental effects on strength gains. At the cellular level, specific protein candidates have been suggested to mediate this training interference; however, at present, the physiological reason(s) behind the concurrent training effect remain largely unknown. Even less is known regarding the optimal nutritional strategies to support concurrent training and whether unique nutritional approaches are needed to support endurance and resistance exercise during concurrent training approaches. In this review, we will discuss the importance of protein supplementation for both endurance and resistance training adaptation and highlight additional nutritional strategies that may support concurrent training. Finally, we will attempt to synergise current understanding of the interaction between physiological responses and nutritional approaches into practical recommendations for concurrent training.

Efficient sampling of complex network with modified random walk strategies

Science.gov (United States)

Xie, Yunya; Chang, Shuhua; Zhang, Zhipeng; Zhang, Mi; Yang, Lei

2018-02-01

We present two novel random walk strategies, choosing seed node (CSN) random walk and no-retracing (NR) random walk. Different from the classical random walk sampling, the CSN and NR strategies focus on the influences of the seed node choice and path overlap, respectively. Three random walk samplings are applied in the Erdös-Rényi (ER), Barabási-Albert (BA), Watts-Strogatz (WS), and the weighted USAir networks, respectively. Then, the major properties of sampled subnets, such as sampling efficiency, degree distributions, average degree and average clustering coefficient, are studied. The similar conclusions can be reached with these three random walk strategies. Firstly, the networks with small scales and simple structures are conducive to the sampling. Secondly, the average degree and the average clustering coefficient of the sampled subnet tend to the corresponding values of original networks with limited steps. And thirdly, all the degree distributions of the subnets are slightly biased to the high degree side. However, the NR strategy performs better for the average clustering coefficient of the subnet. In the real weighted USAir networks, some obvious characters like the larger clustering coefficient and the fluctuation of degree distribution are reproduced well by these random walk strategies.

Site-Wide Integrated Water Monitoring - Defining and Implementing Sampling Objectives to Support Site Closure - 13060

International Nuclear Information System (INIS)

Wilborn, Bill; Knapp, Kathryn; Farnham, Irene; Marutzky, Sam

2013-01-01

The Underground Test Area (UGTA) activity is responsible for assessing and evaluating the effects of the underground nuclear weapons tests on groundwater at the Nevada National Security Site (NNSS), formerly the Nevada Test Site (NTS), and implementing a corrective action closure strategy. The UGTA strategy is based on a combination of characterization, modeling studies, monitoring, and institutional controls (i.e., monitored natural attenuation). The closure strategy verifies through appropriate monitoring activities that contaminants of concern do not exceed the SDWA at the regulatory boundary and that adequate institutional controls are established and administered to ensure protection of the public. Other programs conducted at the NNSS supporting the environmental mission include the Routine Radiological Environmental Monitoring Program (RREMP), Waste Management, and the Infrastructure Program. Given the current programmatic and operational demands for various water-monitoring activities at the same locations, and the ever-increasing resource challenges, cooperative and collaborative approaches to conducting the work are necessary. For this reason, an integrated sampling plan is being developed by the UGTA activity to define sampling and analysis objectives, reduce duplication, eliminate unnecessary activities, and minimize costs. The sampling plan will ensure the right data sets are developed to support closure and efficient transition to long-term monitoring. The plan will include an integrated reporting mechanism for communicating results and integrating process improvements within the UGTA activity as well as between other U.S. Department of Energy (DOE) Programs. (authors)

Quality of life, coping strategies, social support and self-efficacy in women after acute myocardial infarction: a mixed methods approach.

Science.gov (United States)

Fuochi, G; Foà, C

2018-03-01

Quality of life, coping strategies, social support and self-efficacy are important psychosocial variables strongly affecting the experience of acute myocardial infarction (AMI) in women. To gain a more in-depth understanding of how coping strategies, self-efficacy, quality of life and social support shape women's adjustment to AMI. Mixed methods study. Quantitative data were collected through a standardised questionnaire on coping strategies, self-efficacy, quality of life and social support. Qualitative data stemmed from 57 semistructured interviews conducted with post-AMI female patients on related topics. Quantitative data were analysed with unpaired two-sample t-tests on the means, comparing women who experienced AMI (N = 77) with a control group of women who did not have AMI (N = 173), and pairwise correlations on the AMI sample. Qualitative data were grouped into coding families and analysed through thematic content analysis. Qualitative and quantitative results were then integrated, for different age groups. Quantitative results indicated statistically significant differences between women who experienced AMI and the control group: the former showed lower self-perceived health, perceived social support and social support coping, but greater self-efficacy, use of acceptance, avoidance and religious coping. Pairwise correlations showed that avoidance coping strategy was negatively correlated with quality of life, while the opposite was true for problem-oriented coping, perceived social support and self-efficacy. Qualitative results extended and confirmed quantitative results, except for coping strategies: avoidance coping seemed more present than reported in the standardised measures. Mixed methods provide understanding of the importance of social support, self-efficacy and less avoidant coping strategies to women's adjustment to AMI. Women need support from health professionals with knowledge of these topics, to facilitate their adaptation to AMI. © 2017

A Bayesian sampling strategy for hazardous waste site characterization

International Nuclear Information System (INIS)

Skalski, J.R.

1987-12-01

Prior knowledge based on historical records or physical evidence often suggests the existence of a hazardous waste site. Initial surveys may provide additional or even conflicting evidence of site contamination. This article presents a Bayes sampling strategy that allocates sampling at a site using this prior knowledge. This sampling strategy minimizes the environmental risks of missing chemical or radionuclide hot spots at a waste site. The environmental risk is shown to be proportional to the size of the undetected hot spot or inversely proportional to the probability of hot spot detection. 12 refs., 2 figs

Ingredients for Success: Strategies to Support Local Food Use in Health Care Institutions.

Science.gov (United States)

Linton, Emily; Keller, Heather; Duizer, Lisa

2018-06-12

There is growing interest in use of local food within health care institutions such as hospitals and long-term care homes. This study explored stakeholder perspectives on (i) influences on local food use and (ii) strategies that support success and sustainability of use in health care institutions. Fifteen participants who were institutional leaders with experience in implementing or supporting local food use in health care institutions in Ontario were recruited through purposeful and snowball sampling. A semi-structured interview was conducted by telephone and audio-recorded. Qualitative content analysis identified that influences on local food use were: product availability, staff and management engagement, and legislation and resources (e.g., funding, labour). Several strategies were offered for building and sustaining success including: setting goals, requesting local food availability from suppliers, and more clearly identifying local foods in product lists. The influences and potential strategies highlighted in this paper provide a greater understanding for dietitians and food service managers on how local foods can be incorporated into health care institutions.

Disclosure strategies, social support, and quality of life in infertile women.

Science.gov (United States)

Steuber, Keli R; High, Andrew

2015-07-01

fully mediates the association between direct disclosures and fertility quality of life. The cross-sectional nature of our convenient sample did not allow us to test cause and effect. It is equally plausible that women who perceive support are more likely to disclose. Longitudinal data are necessary to test the cyclic nature of these variables and confirm directionality. When women make the decision to reveal information about their infertility, direct disclosure (i.e. face-to-face, clearly, verbally and with the opportunity for an immediate response) was the only strategy that significantly corresponded with perceived support quality and was one of only two strategies that were positively associated with quality of life. To the extent that social support reduces stress, and lower stress increases the chance that people seek and stay in treatment, infertility clinics and therapists can use this information as a low-cost strategy for supporting infertile women. Scholars and practitioners can also instruct women coping with infertility about how to most effectively engage in seeking effective support. No external funding was either sought or obtained for this study and no competing interests are declared. © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Perceptual support promotes strategy generation: Evidence from equation solving.

Science.gov (United States)

Alibali, Martha W; Crooks, Noelle M; McNeil, Nicole M

2017-08-30

Over time, children shift from using less optimal strategies for solving mathematics problems to using better ones. But why do children generate new strategies? We argue that they do so when they begin to encode problems more accurately; therefore, we hypothesized that perceptual support for correct encoding would foster strategy generation. Fourth-grade students solved mathematical equivalence problems (e.g., 3 + 4 + 5 = 3 + __) in a pre-test. They were then randomly assigned to one of three perceptual support conditions or to a Control condition. Participants in all conditions completed three mathematical equivalence problems with feedback about correctness. Participants in the experimental conditions received perceptual support (i.e., highlighting in red ink) for accurately encoding the equal sign, the right side of the equation, or the numbers that could be added to obtain the correct solution. Following this intervention, participants completed a problem-solving post-test. Among participants who solved the problems incorrectly at pre-test, those who received perceptual support for correctly encoding the equal sign were more likely to generate new, correct strategies for solving the problems than were those who received feedback only. Thus, perceptual support for accurate encoding of a key problem feature promoted generation of new, correct strategies. Statement of Contribution What is already known on this subject? With age and experience, children shift to using more effective strategies for solving math problems. Problem encoding also improves with age and experience. What the present study adds? Support for encoding the equal sign led children to generate correct strategies for solving equations. Improvements in problem encoding are one source of new strategies. © 2017 The British Psychological Society.

Strategy generator in computerized accident management support system

International Nuclear Information System (INIS)

Sirola, M.

1994-02-01

An increased interest for research in the field of accident management of nuclear power plants can be noted. Several international programmes have been started in order to be able to understand the basic physical and chemical phenomena in accident conditions. A feasibility study has shown that it would be possible to design and develop a computerized support system for plant staff in accident situations. To achieve this goal the Halden Project has initiated a research programme on Computerized Accident Management Support (CAMS project). The aim is to utilize the capabilities of computerized tools to support the plant staff during the various accident stages. The system will include identification of the accident state, assessment of the future development of the accident and planning of accident mitigation strategies. A prototype is developed to support operators and the Technical Support Centre in decision making during serious accidents in nuclear power plants. A rule based system has been built to take care of the strategy generation. This system assists plant personnel in planning control proposals and mitigation strategies from normal operation to severe accident conditions. The idea of a safety objective tree and knowledge from the emergency procedures have been used. Future prediction requires good state identification of the plant status and some knowledge about the history of some critical variables. The information needs to be validated as well. Accurate calculations in simulators and a large database including all important information from the plant will help the strategy planning. (orig.). (40 refs., 20 figs.)

Management accounting in support of strategy - a strategy as practice perspective

OpenAIRE

Pitcher, GS

2014-01-01

The term Strategic Management Accounting (SMA) was coined in the 1980's to both describe and encourage the development of accounting techniques that addressed strategic decision-making. This prompted the production of books and research papers into SMA techniques. However, there is very little research into how management accounting supports strategy making. Adopting the lens of strategy-as-practice and utilising a narrative research \\ud approach this developmental paper addresses the questio...

Females' sampling strategy to comparatively evaluate prospective mates in the peacock blenny Salaria pavo

Science.gov (United States)

Locatello, Lisa; Rasotto, Maria B.

2017-08-01

Emerging evidence suggests the occurrence of comparative decision-making processes in mate choice, questioning the traditional idea of female choice based on rules of absolute preference. In such a scenario, females are expected to use a typical best-of- n sampling strategy, being able to recall previous sampled males based on memory of their quality and location. Accordingly, the quality of preferred mate is expected to be unrelated to both the number and the sequence of female visits. We found support for these predictions in the peacock blenny, Salaria pavo, a fish where females have the opportunity to evaluate the attractiveness of many males in a short time period and in a restricted spatial range. Indeed, even considering the variability in preference among females, most of them returned to previous sampled males for further evaluations; thus, the preferred male did not represent the last one in the sequence of visited males. Moreover, there was no relationship between the attractiveness of the preferred male and the number of further visits assigned to the other males. Our results suggest the occurrence of a best-of- n mate sampling strategy in the peacock blenny.

Sample collection and sample analysis plan in support of the 105-C/190-C concrete and soil sampling activities

International Nuclear Information System (INIS)

Marske, S.G.

1996-07-01

This sampling and analysis plan describes the sample collection and sample analysis in support of the 105-C water tunnels and 190-C main pumphouse concrete and soil sampling activities. These analytical data will be used to identify the radiological contamination and presence of hazardous materials to support the decontamination and disposal activities

The Role of Perceived Teacher's Support and Motivational Orientation in Prediction of Metacognitive Awareness of Reading Strategies in Learning English

Directory of Open Access Journals (Sweden)

Zohreh Kazemi

2016-08-01

Full Text Available This study aims to determine the role of perceived teacher support and motivational orientation in predicting metacognitive awareness of reading strategies in learning the English language. The sample included 425 male and female students, studying in the elementary schools in the city of Birjand, eastern Iran, in the 2014-2015 academic year. Three different types of questionnaires were distributed among these students. The questionnaires were, respectively, about the students’ perception of teacher support (Zaki, 2007, motivational orientation for English learning (Sheikholeslami, 2005, and metacognitive awareness of the study methods (Mokhtari & Richard, 2002. Multiple regression analysis was applied to analyze the obtained data. It was found that there was a direct and significant correlation between teacher support variable, and intrinsic motivation, overall reading strategies, problem-solving strategies, reading support strategies, and metacognitive awareness. Additionally, there was an inverse and significant correlation with the non-motivation variable. Furthermore, no significant correlation was observed between the teacher support variable and the extrinsic motivation variable. A direct and significant relationship was, however, spotted between intrinsic motivation, and extrinsic motivation, overall reading strategies, problem-solving strategies, reading support strategies,and metacognitive awareness; and an inverse and significant relationship was noticed between the intrinsic motivation and non-motivation variables. Moreover, there existed a direct and significant relationship between extrinsic motivation, and overall reading strategies, problem-solving strategies, reading support strategies, metacognitive awareness and it had an inverse and significant relationship with non-motivation variable. The findings demonstrated that the components of perceived teacher support and motivational orientation (extrinsic motivation, intrinsic

Paraffin scintillator for radioassay of solid support samples

International Nuclear Information System (INIS)

Fujii, Haruo; Takiue, Makoto

1989-01-01

A new paraffin scintillator used for solid support sample counting has been proposed, and its composition and various characteristics are described. The solid support sample treated with this scintillator can be easily handled because of rigid sample conditions. This technique provides great advantages such as the elimination of a large volume of scintillator and little radioactive waste material by using an economical polyethylene bag instead of the conventional counting vial. (author)

Measuring strategy of Support Centre RIVM for nuclear emergencies

International Nuclear Information System (INIS)

Pruppers, M.J.M.; Smetsers, R.C.G.M.

1994-11-01

The accident at the Chernobyl nuclear power station in April 1986 and its consequences were reason for the Dutch government to evaluate and improve the facilities and the preparedness for nuclear emergency management in the Netherlands. The results of the evaluation have been elaborated in operational terms in the National Plan for Nuclear Emergency Planning and Response (EPR). During an accident with radioactive material the Technical Information Group (TIG) coordinates the measuring activities of the so-called Support Centres. According to the EPR, measuring activities of Support Centre RIVM are focussed on the collection and processing of data on emissions, concentrations, depositions and radiation doses from soil and air. This report describes the measuring strategy of RIVM for nuclear emergencies. The measuring strategy and the measuring plan, the latter deduced from the measuring strategy, concentrate on explicit answers to the following central questions: what has to be measured, by whom, where, when and how, and why? The demands of the TIG and the specification of tasks and operational facilities of Support Centre RIVM are considered as starting-points, limiting conditions and constraints for the measuring strategy. These items are converted to explicit choices for the measuring strategy and the default measuring plan. This report further includes a list of contacts of Support Centre RIVM with other (research) institutes, inside and outside the Netherlands, which may be relevant during a nuclear emergency. 3 figs., 2 tabs., 22 refs

Sampling strategies in antimicrobial resistance monitoring: evaluating how precision and sensitivity vary with the number of animals sampled per farm.

Directory of Open Access Journals (Sweden)

Takehisa Yamamoto

Full Text Available Because antimicrobial resistance in food-producing animals is a major public health concern, many countries have implemented antimicrobial monitoring systems at a national level. When designing a sampling scheme for antimicrobial resistance monitoring, it is necessary to consider both cost effectiveness and statistical plausibility. In this study, we examined how sampling scheme precision and sensitivity can vary with the number of animals sampled from each farm, while keeping the overall sample size constant to avoid additional sampling costs. Five sampling strategies were investigated. These employed 1, 2, 3, 4 or 6 animal samples per farm, with a total of 12 animals sampled in each strategy. A total of 1,500 Escherichia coli isolates from 300 fattening pigs on 30 farms were tested for resistance against 12 antimicrobials. The performance of each sampling strategy was evaluated by bootstrap resampling from the observational data. In the bootstrapping procedure, farms, animals, and isolates were selected randomly with replacement, and a total of 10,000 replications were conducted. For each antimicrobial, we observed that the standard deviation and 2.5-97.5 percentile interval of resistance prevalence were smallest in the sampling strategy that employed 1 animal per farm. The proportion of bootstrap samples that included at least 1 isolate with resistance was also evaluated as an indicator of the sensitivity of the sampling strategy to previously unidentified antimicrobial resistance. The proportion was greatest with 1 sample per farm and decreased with larger samples per farm. We concluded that when the total number of samples is pre-specified, the most precise and sensitive sampling strategy involves collecting 1 sample per farm.

Socioeconomic Factors Affecting Local Support for Black Bear Recovery Strategies

Science.gov (United States)

Morzillo, Anita T.; Mertig, Angela G.; Hollister, Jeffrey W.; Garner, Nathan; Liu, Jianguo

2010-06-01

There is global interest in recovering locally extirpated carnivore species. Successful efforts to recover Louisiana black bear in Louisiana have prompted interest in recovery throughout the species’ historical range. We evaluated support for three potential black bear recovery strategies prior to public release of a black bear conservation and management plan for eastern Texas, United States. Data were collected from 1,006 residents living in proximity to potential recovery locations, particularly Big Thicket National Preserve. In addition to traditional logistic regression analysis, we used conditional probability analysis to statistically and visually evaluate probabilities of public support for potential black bear recovery strategies based on socioeconomic characteristics. Allowing black bears to repopulate the region on their own (i.e., without active reintroduction) was the recovery strategy with the greatest probability of acceptance. Recovery strategy acceptance was influenced by many socioeconomic factors. Older and long-time local residents were most likely to want to exclude black bears from the area. Concern about the problems that black bears may cause was the only variable significantly related to support or non-support across all strategies. Lack of personal knowledge about black bears was the most frequent reason for uncertainty about preferred strategy. In order to reduce local uncertainty about possible recovery strategies, we suggest that wildlife managers focus outreach efforts on providing local residents with general information about black bears, as well as information pertinent to minimizing the potential for human-black bear conflict.

strategies for the support of successful land reform

African Journals Online (AJOL)

lynette

players to deliver efficient support programs for newly settled farmers. This can only be achieved ... government support services, such as extension services. 2 ... growth strategy, focusing on raising productivity in areas of comparative ... health of agricultural laborers and promoted cottage industry. .... Sourcing of finance. 55.

Effective sampling strategy to detect food and feed contamination

NARCIS (Netherlands)

Bouzembrak, Yamine; Fels, van der Ine

2018-01-01

Sampling plans for food safety hazards are aimed to be used to determine whether a lot of food is contaminated (with microbiological or chemical hazards) or not. One of the components of sampling plans is the sampling strategy. The aim of this study was to compare the performance of three

Novel strategies for sample preparation in forensic toxicology.

Science.gov (United States)

Samanidou, Victoria; Kovatsi, Leda; Fragou, Domniki; Rentifis, Konstantinos

2011-09-01

This paper provides a review of novel strategies for sample preparation in forensic toxicology. The review initially outlines the principle of each technique, followed by sections addressing each class of abused drugs separately. The novel strategies currently reviewed focus on the preparation of various biological samples for the subsequent determination of opiates, benzodiazepines, amphetamines, cocaine, hallucinogens, tricyclic antidepressants, antipsychotics and cannabinoids. According to our experience, these analytes are the most frequently responsible for intoxications in Greece. The applications of techniques such as disposable pipette extraction, microextraction by packed sorbent, matrix solid-phase dispersion, solid-phase microextraction, polymer monolith microextraction, stir bar sorptive extraction and others, which are rapidly gaining acceptance in the field of toxicology, are currently reviewed.

Strategies to Support Ethical Reasoning in Student Argumentation

Science.gov (United States)

Carlton Griswold, Joan; Ting Chowning, Jean

2013-01-01

This article discusses the importance and benefits of incorporating ethics\tinto the classroom and presents five strategies that both scaffold students'\tunderstanding of ethical issues and support students' abilities to come to a reasoned and well-supported decision about those issues. (Contains 1 table and 4 notes.)

Coping with Workplace Violence against General Practitioners and Nurses in Heilongjiang Province, China: Social Supports and Prevention Strategies.

Science.gov (United States)

Zhao, Siqi; Qu, Lijun; Liu, He; Gao, Lijun; Jiao, Mingli; Liu, Jinghua; Liang, Libo; Zhao, Yanming; Wu, Qunhong

2016-01-01

The study's objectives were to: 1) use social support theory to examine factors influencing healthcare workers' opinions about workplace violence (WPV) prevention strategies, and 2) to determine the types of support that general practitioners (GPs) and general nurses sought and expected to use after WPV exposure. A cross-sectional survey was used to assess a sample of 448 GPs and 412 general nurses from 90 township hospitals located in Heilongjiang province, China. Results revealed that workers exposed to physical, psychological or both WPV types had a strong opinion about the necessity of improving diagnosis/treatment competence, developing violence prevention guidelines and plans, using protective equipment, and reinforcing staff by providing back-up support. The last two strategies were also selected by tertiary hospital workers in our previous study. In addition, workers with high anxiety selected the following prevention strategies as most effective: improving doctor-patient communication skills; installing cameras on wards; keeping work areas bright; improvements in violence reporting, statistics, and interventions; security patrols in the key departments; reinforcing staff; and correcting inaccurate media perspectives and reports. The last four strategies were also selected by tertiary hospital workers. All respondents expected to receive organisational and social support. In conclusion, these prevention strategies should be tailored to the different requirements of specific populations. Furthermore, it is necessary for organisations, the public, and policymakers to provide powerful support in WPV prevention.

Decision Strategy Research: Policy Support

International Nuclear Information System (INIS)

Hardeman, F.

2000-01-01

The objective of SCK-CEN's R and D programme on decision strategy research are (1) to support and advise the Belgian authorities on specific problems concerning existing and potential hazards from exposure to ionising radiation, both in normal and emergency situations; (2) to perform research on relevant topics that might have an important impact on decision making related to nuclear applications, including social and economic sciences. Main achievements in this area in 1999 are described

Limited-sampling strategies for anti-infective agents: systematic review.

Science.gov (United States)

Sprague, Denise A; Ensom, Mary H H

2009-09-01

Area under the concentration-time curve (AUC) is a pharmacokinetic parameter that represents overall exposure to a drug. For selected anti-infective agents, pharmacokinetic-pharmacodynamic parameters, such as AUC/MIC (where MIC is the minimal inhibitory concentration), have been correlated with outcome in a few studies. A limited-sampling strategy may be used to estimate pharmacokinetic parameters such as AUC, without the frequent, costly, and inconvenient blood sampling that would be required to directly calculate the AUC. To discuss, by means of a systematic review, the strengths, limitations, and clinical implications of published studies involving a limited-sampling strategy for anti-infective agents and to propose improvements in methodology for future studies. The PubMed and EMBASE databases were searched using the terms "anti-infective agents", "limited sampling", "optimal sampling", "sparse sampling", "AUC monitoring", "abbreviated AUC", "abbreviated sampling", and "Bayesian". The reference lists of retrieved articles were searched manually. Included studies were classified according to modified criteria from the US Preventive Services Task Force. Twenty studies met the inclusion criteria. Six of the studies (involving didanosine, zidovudine, nevirapine, ciprofloxacin, efavirenz, and nelfinavir) were classified as providing level I evidence, 4 studies (involving vancomycin, didanosine, lamivudine, and lopinavir-ritonavir) provided level II-1 evidence, 2 studies (involving saquinavir and ceftazidime) provided level II-2 evidence, and 8 studies (involving ciprofloxacin, nelfinavir, vancomycin, ceftazidime, ganciclovir, pyrazinamide, meropenem, and alpha interferon) provided level III evidence. All of the studies providing level I evidence used prospectively collected data and proper validation procedures with separate, randomly selected index and validation groups. However, most of the included studies did not provide an adequate description of the methods or

Supporting FEI through innovation strategy implementation

DEFF Research Database (Denmark)

Aagaard, Annabeth

the ‘predictability’ of the discovery process/FEI ought to be an immediate priority area of investment for Pharma (Duyck, 2003). This paper explores how pharmaceutical front end innovation can be actively supported through the development and implementation of an innovation strategy. The empirical field......-year Ph.D. study the process of identifying, developing and integrating a targeted innovation corporate strategy and divisional action plans is examined and effects and results are evaluated and measured. The findings and key learnings from the study are presented as propositions of how innovation......, Steven & Burly, 2003, and Vernorn et al., 2008) and that innovation strategies play a central role in optimization of innovation (Clark & Wheelwright, 1995; Cottam et al., 2001; Morgan & Berthon, 2008). Cottam et al. (2001) stress that in order to maximize the benefits of previous innovations innovative...

[Strategies for biobank networks. Classification of different approaches for locating samples and an outlook on the future within the BBMRI-ERIC].

Science.gov (United States)

Lablans, Martin; Kadioglu, Dennis; Mate, Sebastian; Leb, Ines; Prokosch, Hans-Ulrich; Ückert, Frank

2016-03-01

Medical research projects often require more biological material than can be supplied by a single biobank. For this reason, a multitude of strategies support locating potential research partners with matching material without requiring centralization of sample storage. Classification of different strategies for biobank networks, in particular for locating suitable samples. Description of an IT infrastructure combining these strategies. Existing strategies can be classified according to three criteria: (a) granularity of sample data: coarse bank-level data (catalogue) vs. fine-granular sample-level data, (b) location of sample data: central (central search service) vs. decentral storage (federated search services), and (c) level of automation: automatic (query-based, federated search service) vs. semi-automatic (inquiry-based, decentral search). All mentioned search services require data integration. Metadata help to overcome semantic heterogeneity. The "Common Service IT" in BBMRI-ERIC (Biobanking and BioMolecular Resources Research Infrastructure) unites a catalogue, the decentral search and metadata in an integrated platform. As a result, researchers receive versatile tools to search suitable biomaterial, while biobanks retain a high degree of data sovereignty. Despite their differences, the presented strategies for biobank networks do not rule each other out but can complement and even benefit from each other.

A guided note taking strategy supports student learning in the large lecture classes

Science.gov (United States)

Tanamatayarat, J.; Sujarittham, T.; Wuttiprom, S.; Hefer, E.

2017-09-01

In higher education, lecturing has been found to be the most prevalent teaching format for large classes. Generally, this format tends not to result in effective learning outcomes. Therefore, to support student learning in these large lecture classes, we developed guided notes containing quotations, blank spaces, pictures, and problems. A guided note taking strategy was selected and has been used in our introductory physics course for many years. In this study, we investigated the results of implementing the guided note taking strategy to promote student learning on electrostatics. The samples were three groups of first-year students from two universities: 163 and 224 science students and 147 engineering students. All of the students were enrolled in the introductory physics course in the second semester. To assess the students’ understanding, we administered pre- and post-tests to the students by using the electrostatics test. The questions were selected from the conceptual survey of electricity and magnetism (CSEM) and some leading physics textbooks. The results of the students’ understanding were analyzed by the average normalized gains (). The value of each group was 0.61, 0.55, and 0.54, respectively. Furthermore, the students’ views on learning with the guided note taking strategy were explored by using the five-point rating scale survey. Most students perceived that the strategy helped support their active learning and engagement in the lectures.

Potential-Decomposition Strategy in Markov Chain Monte Carlo Sampling Algorithms

International Nuclear Information System (INIS)

Shangguan Danhua; Bao Jingdong

2010-01-01

We introduce the potential-decomposition strategy (PDS), which can he used in Markov chain Monte Carlo sampling algorithms. PDS can be designed to make particles move in a modified potential that favors diffusion in phase space, then, by rejecting some trial samples, the target distributions can be sampled in an unbiased manner. Furthermore, if the accepted trial samples are insufficient, they can be recycled as initial states to form more unbiased samples. This strategy can greatly improve efficiency when the original potential has multiple metastable states separated by large barriers. We apply PDS to the 2d Ising model and a double-well potential model with a large barrier, demonstrating in these two representative examples that convergence is accelerated by orders of magnitude.

A comparative proteomics method for multiple samples based on a 18O-reference strategy and a quantitation and identification-decoupled strategy.

Science.gov (United States)

Wang, Hongbin; Zhang, Yongqian; Gui, Shuqi; Zhang, Yong; Lu, Fuping; Deng, Yulin

2017-08-15

Comparisons across large numbers of samples are frequently necessary in quantitative proteomics. Many quantitative methods used in proteomics are based on stable isotope labeling, but most of these are only useful for comparing two samples. For up to eight samples, the iTRAQ labeling technique can be used. For greater numbers of samples, the label-free method has been used, but this method was criticized for low reproducibility and accuracy. An ingenious strategy has been introduced, comparing each sample against a 18 O-labeled reference sample that was created by pooling equal amounts of all samples. However, it is necessary to use proportion-known protein mixtures to investigate and evaluate this new strategy. Another problem for comparative proteomics of multiple samples is the poor coincidence and reproducibility in protein identification results across samples. In present study, a method combining 18 O-reference strategy and a quantitation and identification-decoupled strategy was investigated with proportion-known protein mixtures. The results obviously demonstrated that the 18 O-reference strategy had greater accuracy and reliability than other previously used comparison methods based on transferring comparison or label-free strategies. By the decoupling strategy, the quantification data acquired by LC-MS and the identification data acquired by LC-MS/MS are matched and correlated to identify differential expressed proteins, according to retention time and accurate mass. This strategy made protein identification possible for all samples using a single pooled sample, and therefore gave a good reproducibility in protein identification across multiple samples, and allowed for optimizing peptide identification separately so as to identify more proteins. Copyright © 2017 Elsevier B.V. All rights reserved.

Acculturation Strategies, Social Support, and Cross-Cultural Adaptation: A Mediation Analysis

Science.gov (United States)

Ng, Ting Kin; Tsang, Kwok Kuen; Lian, Yi

2013-01-01

Previous acculturation research has established the influences of acculturation strategies and social support on cross-cultural adaptation. The present study attempted to elaborate these direct associations by proposing that social support and the use of the integration and marginalization strategies might affect psychological adaptation…

Coping with Workplace Violence against General Practitioners and Nurses in Heilongjiang Province, China: Social Supports and Prevention Strategies

Science.gov (United States)

Liu, He; Gao, Lijun; Jiao, Mingli; Liu, Jinghua; Liang, Libo; Zhao, Yanming; Wu, Qunhong

2016-01-01

The study’s objectives were to: 1) use social support theory to examine factors influencing healthcare workers’ opinions about workplace violence (WPV) prevention strategies, and 2) to determine the types of support that general practitioners (GPs) and general nurses sought and expected to use after WPV exposure. A cross-sectional survey was used to assess a sample of 448 GPs and 412 general nurses from 90 township hospitals located in Heilongjiang province, China. Results revealed that workers exposed to physical, psychological or both WPV types had a strong opinion about the necessity of improving diagnosis/treatment competence, developing violence prevention guidelines and plans, using protective equipment, and reinforcing staff by providing back-up support. The last two strategies were also selected by tertiary hospital workers in our previous study. In addition, workers with high anxiety selected the following prevention strategies as most effective: improving doctor-patient communication skills; installing cameras on wards; keeping work areas bright; improvements in violence reporting, statistics, and interventions; security patrols in the key departments; reinforcing staff; and correcting inaccurate media perspectives and reports. The last four strategies were also selected by tertiary hospital workers. All respondents expected to receive organisational and social support. In conclusion, these prevention strategies should be tailored to the different requirements of specific populations. Furthermore, it is necessary for organisations, the public, and policymakers to provide powerful support in WPV prevention. PMID:27326460

Coping with Workplace Violence against General Practitioners and Nurses in Heilongjiang Province, China: Social Supports and Prevention Strategies.

Directory of Open Access Journals (Sweden)

Siqi Zhao

Full Text Available The study's objectives were to: 1 use social support theory to examine factors influencing healthcare workers' opinions about workplace violence (WPV prevention strategies, and 2 to determine the types of support that general practitioners (GPs and general nurses sought and expected to use after WPV exposure. A cross-sectional survey was used to assess a sample of 448 GPs and 412 general nurses from 90 township hospitals located in Heilongjiang province, China. Results revealed that workers exposed to physical, psychological or both WPV types had a strong opinion about the necessity of improving diagnosis/treatment competence, developing violence prevention guidelines and plans, using protective equipment, and reinforcing staff by providing back-up support. The last two strategies were also selected by tertiary hospital workers in our previous study. In addition, workers with high anxiety selected the following prevention strategies as most effective: improving doctor-patient communication skills; installing cameras on wards; keeping work areas bright; improvements in violence reporting, statistics, and interventions; security patrols in the key departments; reinforcing staff; and correcting inaccurate media perspectives and reports. The last four strategies were also selected by tertiary hospital workers. All respondents expected to receive organisational and social support. In conclusion, these prevention strategies should be tailored to the different requirements of specific populations. Furthermore, it is necessary for organisations, the public, and policymakers to provide powerful support in WPV prevention.

Database system selection for marketing strategies support in information systems

Directory of Open Access Journals (Sweden)

František Dařena

2007-01-01

Full Text Available In today’s dynamically changing environment marketing has a significant role. Creating successful marketing strategies requires large amount of high quality information of various kinds and data types. A powerful database management system is a necessary condition for marketing strategies creation support. The paper briefly describes the field of marketing strategies and specifies the features that should be provided by database systems in connection with these strategies support. Major commercial (Oracle, DB2, MS SQL, Sybase and open-source (PostgreSQL, MySQL, Firebird databases are than examined from the point of view of accordance with these characteristics and their comparison in made. The results are useful for making the decision before acquisition of a database system during information system’s hardware architecture specification.

Doctors with dyslexia: strategies and support.

Science.gov (United States)

Locke, Rachel; Alexander, Gail; Mann, Richard; Kibble, Sharon; Scallan, Samantha

2017-10-01

Looking beyond dyslexia as an individual doctor's issue requires adjusting a working environment to better serve the needs of doctors with dyslexia. With an increasing number of doctors disclosing dyslexia at medical school, how can educators best provide this support? Our research looks at the impact of dyslexia on clinical practice and the coping strategies used by doctors to minimise the effect. Qualitative data were collected from 14 doctors with dyslexia using semi-structured interviews and by survey. 'In situ' demonstration interviews were conducted in order to understand how dyslexia is managed in the workplace from first-hand experience. Employers and educators who have responsibility for meeting the needs of this group were also consulted. Even in cases of doctors who had a diagnosis, they often did not disclose their dyslexia to their employer. Study participants reported having developed individual ways of coping and devised useful 'workarounds'. Support from employers comes in the form of 'reasonable adjustments', although from our data we cannot be sure that such adjustments contribute to an 'enabling' work environment. Supportive characteristics included the opportunity to shadow others and the time and space to complete paperwork on a busy ward. How can educators best provide support [for doctors with dyslexia]? Doctors with dyslexia need to be helped to feel comfortable enough to disclose. Educators need to challenge any negative assumptions that exist as well as promote understanding about the elements that contribute to a positive working environment. As a result of the research there is now practice available for educators to identify evidence-based strategies and resources. © 2016 John Wiley & Sons Ltd and The Association for the Study of Medical Education.

The Integrated Scorecard in support of corporate sustainability strategies.

Science.gov (United States)

Journeault, Marc

2016-11-01

Organizations have increasingly recognized the importance and benefits of developing a sustainability strategy that incorporates environmental and social responsibilities. However, the simultaneous integration of the economic, environmental and social aspects remains a major concern for organizations. The Sustainability Balanced Scorecard (SBSC) represents one of the most promising strategic tools to help organizations face these challenges and support their sustainability strategy. However, past research has provided unclear, incomplete and even contradictory SBSC frameworks while offering little knowledge about how to integrate stakeholder management as well as environmental and social performance within the balanced scorecard to successfully support a corporate sustainability strategy. The aim of this study is to address these issues and limitations by proposing the Integrated Scorecard, a specific SBSC that integrates the three pillars of sustainability performance within four different perspectives, namely environmental, social and economic performance, stakeholder management, internal business processes, and skills and capabilities. This study provides a conceptual approach to the Integrated Scorecard and illustrates, through the use of two practical illustrations, the ability of this framework to support the corporate sustainability strategy by identifying the core sustainability objectives that organizations should achieve when creating value, facilitating the understanding of the contribution of environmental and social initiatives on economic performance, allowing the monitoring and measurement of the strategy's level of achievement, and creating synergy between sustainability performance management and reporting. Copyright © 2016 Elsevier Ltd. All rights reserved.

Support, shape and number of replicate samples for tree foliage analysis.

Science.gov (United States)

Luyssaert, Sebastiaan; Mertens, Jan; Raitio, Hannu

2003-06-01

Many fundamental features of a sampling program are determined by the heterogeneity of the object under study and the settings for the error (alpha), the power (beta), the effect size (ES), the number of replicate samples, and sample support, which is a feature that is often overlooked. The number of replicates, alpha, beta, ES, and sample support are interconnected. The effect of the sample support and its shape on the required number of replicate samples was investigated by means of a resampling method. The method was applied to a simulated distribution of Cd in the crown of a Salix fragilis L. tree. Increasing the dimensions of the sample support results in a decrease in the variance of the element concentration under study. Analysis of the variance is often the foundation of statistical tests, therefore, valid statistical testing requires the use of a fixed sample support during the experiment. This requirement might be difficult to meet in time-series analyses and long-term monitoring programs. Sample supports have their largest dimension in the direction with the largest heterogeneity, i.e. the direction representing the crown height, and this will give more accurate results than supports with other shapes. Taking the relationships between the sample support and the variance of the element concentrations in tree crowns into account provides guidelines for sampling efficiency in terms of precision and costs. In terms of time, the optimal support to test whether the average Cd concentration of the crown exceeds a threshold value is 0.405 m3 (alpha = 0.05, beta = 0.20, ES = 1.0 mg kg(-1) dry mass). The average weight of this support is 23 g dry mass, and 11 replicate samples need to be taken. It should be noted that in this case the optimal support applies to Cd under conditions similar to those of the simulation, but not necessarily all the examinations for this tree species, element, and hypothesis test.

Memory and communication support in dementia: research-based strategies for caregivers.

Science.gov (United States)

Smith, Erin R; Broughton, Megan; Baker, Rosemary; Pachana, Nancy A; Angwin, Anthony J; Humphreys, Michael S; Mitchell, Leander; Byrne, Gerard J; Copland, David A; Gallois, Cindy; Hegney, Desley; Chenery, Helen J

2011-03-01

Difficulties with memory and communication are prominent and distressing features of dementia which impact on the person with dementia and contribute to caregiver stress and burden. There is a need to provide caregivers with strategies to support and maximize memory and communication abilities in people with dementia. In this project, a team of clinicians, researchers and educators in neuropsychology, psychogeriatrics, nursing and speech pathology translated research-based knowledge from these fields into a program of practical strategies for everyday use by family and professional caregivers. From the available research evidence, the project team identified compensatory or facilitative strategies to assist with common areas of difficulty, and structured these under the mnemonics RECAPS (for memory) and MESSAGE (for communication). This information was adapted for presentation in a DVD-based education program in accordance with known characteristics of effective caregiver education. The resultant DVD comprises (1) information on the nature and importance of memory and communication in everyday life; (2) explanations of common patterns of difficulty and preserved ability in memory and communication across the stages of dementia; (3) acted vignettes demonstrating the strategies, based on authentic samples of speech in dementia; and (4) scenarios to prompt the viewer to consider the benefits of using the strategies. Using a knowledge-translation framework, information and strategies can be provided to family and professional caregivers to help them optimize residual memory and communication in people with dementia. Future development of the materials, incorporating consumer feedback, will focus on methods for enabling wider dissemination.

The relative importance of body change strategies, weight perception, perceived social support, and self-esteem on adolescent depressive symptoms: longitudinal findings from a national sample.

Science.gov (United States)

Rawana, Jennine S

2013-07-01

This study aimed to evaluate the relative importance of body change strategies and weight perception in adolescent depression after accounting for established risk factors for depression, namely low social support across key adolescent contexts. The moderating effect of self-esteem was also examined. Participants (N=4587, 49% female) were selected from the National Longitudinal Study of Adolescent Health. Regression analyses were conducted on the association between well-known depression risk factors (lack of perceived support from parents, peers, and schools), body change strategies, weight perception, and adolescent depressive symptoms one year later. Each well-known risk factor significantly predicted depressive symptoms. Body change strategies related to losing weight and overweight perceptions predicted depressive symptoms above and beyond established risk factors. Self-esteem moderated the relationship between trying to lose weight and depressive symptoms. Maladaptive weight loss strategies and overweight perceptions should be addressed in early identification depression programs. Copyright © 2013 Elsevier Inc. All rights reserved.

Relationships between depressive symptoms and perceived social support, self-esteem, & optimism in a sample of rural adolescents.

Science.gov (United States)

Weber, Scott; Puskar, Kathryn Rose; Ren, Dianxu

2010-09-01

Stress, developmental changes and social adjustment problems can be significant in rural teens. Screening for psychosocial problems by teachers and other school personnel is infrequent but can be a useful health promotion strategy. We used a cross-sectional survey descriptive design to examine the inter-relationships between depressive symptoms and perceived social support, self-esteem, and optimism in a sample of rural school-based adolescents. Depressive symptoms were negatively correlated with peer social support, family social support, self-esteem, and optimism. Findings underscore the importance for teachers and other school staff to provide health education. Results can be used as the basis for education to improve optimism, self-esteem, social supports and, thus, depression symptoms of teens.

Measurement of radioactivity in the environment - Soil - Part 2: Guidance for the selection of the sampling strategy, sampling and pre-treatment of samples

International Nuclear Information System (INIS)

2007-01-01

This part of ISO 18589 specifies the general requirements, based on ISO 11074 and ISO/IEC 17025, for all steps in the planning (desk study and area reconnaissance) of the sampling and the preparation of samples for testing. It includes the selection of the sampling strategy, the outline of the sampling plan, the presentation of general sampling methods and equipment, as well as the methodology of the pre-treatment of samples adapted to the measurements of the activity of radionuclides in soil. This part of ISO 18589 is addressed to the people responsible for determining the radioactivity present in soil for the purpose of radiation protection. It is applicable to soil from gardens, farmland, urban or industrial sites, as well as soil not affected by human activities. This part of ISO 18589 is applicable to all laboratories regardless of the number of personnel or the range of the testing performed. When a laboratory does not undertake one or more of the activities covered by this part of ISO 18589, such as planning, sampling or testing, the corresponding requirements do not apply. Information is provided on scope, normative references, terms and definitions and symbols, principle, sampling strategy, sampling plan, sampling process, pre-treatment of samples and recorded information. Five annexes inform about selection of the sampling strategy according to the objectives and the radiological characterization of the site and sampling areas, diagram of the evolution of the sample characteristics from the sampling site to the laboratory, example of sampling plan for a site divided in three sampling areas, example of a sampling record for a single/composite sample and example for a sample record for a soil profile with soil description. A bibliography is provided

Storytelling in organisations: supporting or subverting corporate strategy?

OpenAIRE

Spear, Sara; Roper, Stuart

2016-01-01

Purpose\\ud Storytelling is claimed to be an effective way of communicating corporate strategy within organisations. However, previous studies have tended to focus holistically on storytelling in organisations rather than investigating how different groups may use and be influenced by stories. The purpose of this paper is to address these gaps in the literature by investigating how storytelling in internal communication can either support or subvert corporate strategy.\\ud \\ud Design/methodolog...

A support vector density-based importance sampling for reliability assessment

International Nuclear Information System (INIS)

Dai, Hongzhe; Zhang, Hao; Wang, Wei

2012-01-01

An importance sampling method based on the adaptive Markov chain simulation and support vector density estimation is developed in this paper for efficient structural reliability assessment. The methodology involves the generation of samples that can adaptively populate the important region by the adaptive Metropolis algorithm, and the construction of importance sampling density by support vector density. The use of the adaptive Metropolis algorithm may effectively improve the convergence and stability of the classical Markov chain simulation. The support vector density can approximate the sampling density with fewer samples in comparison to the conventional kernel density estimation. The proposed importance sampling method can effectively reduce the number of structural analysis required for achieving a given accuracy. Examples involving both numerical and practical structural problems are given to illustrate the application and efficiency of the proposed methodology.

Mars Sample Return - Launch and Detection Strategies for Orbital Rendezvous

Science.gov (United States)

Woolley, Ryan C.; Mattingly, Richard L.; Riedel, Joseph E.; Sturm, Erick J.

2011-01-01

This study sets forth conceptual mission design strategies for the ascent and rendezvous phase of the proposed NASA/ESA joint Mars Sample Return Campaign. The current notional mission architecture calls for the launch of an acquisition/cache rover in 2018, an orbiter with an Earth return vehicle in 2022, and a fetch rover and ascent vehicle in 2024. Strategies are presented to launch the sample into a coplanar orbit with the Orbiter which facilitate robust optical detection, orbit determination, and rendezvous. Repeating ground track orbits exist at 457 and 572 km which provide multiple launch opportunities with similar geometries for detection and rendezvous.

Mars Sample Return: Launch and Detection Strategies for Orbital Rendezvous

Science.gov (United States)

Woolley, Ryan C.; Mattingly, Richard L.; Riedel, Joseph E.; Sturm, Erick J.

2011-01-01

This study sets forth conceptual mission design strategies for the ascent and rendezvous phase of the proposed NASA/ESA joint Mars Sample Return Campaign. The current notional mission architecture calls for the launch of an acquisition/ caching rover in 2018, an Earth return orbiter in 2022, and a fetch rover with ascent vehicle in 2024. Strategies are presented to launch the sample into a nearly coplanar orbit with the Orbiter which would facilitate robust optical detection, orbit determination, and rendezvous. Repeating ground track orbits existat 457 and 572 km which would provide multiple launch opportunities with similar geometries for detection and rendezvous.

Random sampling or geostatistical modelling? Choosing between design-based and model-based sampling strategies for soil (with discussion)

NARCIS (Netherlands)

Brus, D.J.; Gruijter, de J.J.

1997-01-01

Classical sampling theory has been repeatedly identified with classical statistics which assumes that data are identically and independently distributed. This explains the switch of many soil scientists from design-based sampling strategies, based on classical sampling theory, to the model-based

How to handle speciose clades? Mass taxon-sampling as a strategy towards illuminating the natural history of Campanula (Campanuloideae.

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Guilhem Mansion

Full Text Available BACKGROUND: Speciose clades usually harbor species with a broad spectrum of adaptive strategies and complex distribution patterns, and thus constitute ideal systems to disentangle biotic and abiotic causes underlying species diversification. The delimitation of such study systems to test evolutionary hypotheses is difficult because they often rely on artificial genus concepts as starting points. One of the most prominent examples is the bellflower genus Campanula with some 420 species, but up to 600 species when including all lineages to which Campanula is paraphyletic. We generated a large alignment of petD group II intron sequences to include more than 70% of described species as a reference. By comparison with partial data sets we could then assess the impact of selective taxon sampling strategies on phylogenetic reconstruction and subsequent evolutionary conclusions. METHODOLOGY/PRINCIPAL FINDINGS: Phylogenetic analyses based on maximum parsimony (PAUP, PRAP, Bayesian inference (MrBayes, and maximum likelihood (RAxML were first carried out on the large reference data set (D680. Parameters including tree topology, branch support, and age estimates, were then compared to those obtained from smaller data sets resulting from "classification-guided" (D088 and "phylogeny-guided sampling" (D101. Analyses of D088 failed to fully recover the phylogenetic diversity in Campanula, whereas D101 inferred significantly different branch support and age estimates. CONCLUSIONS/SIGNIFICANCE: A short genomic region with high phylogenetic utility allowed us to easily generate a comprehensive phylogenetic framework for the speciose Campanula clade. Our approach recovered 17 well-supported and circumscribed sub-lineages. Knowing these will be instrumental for developing more specific evolutionary hypotheses and guide future research, we highlight the predictive value of a mass taxon-sampling strategy as a first essential step towards illuminating the detailed

Support Needs and Coping Strategies as Predictors of Stress Level among Mothers of Children with Autism Spectrum Disorder

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Sheri R. Kiami

2017-01-01

Full Text Available This study examined maternal stress, coping strategies, and support needs among mothers of children with Autism Spectrum Disorder (ASD. A convenience sample of 70 mothers completed the Parent Stress Index Short Form (PSI-SF, Coping Health Inventory for Parents (CHIP, and Modified Family Needs Questionnaire (FNQ. PSI-SF scores reflected clinically significant levels of stress for 77% of mothers, and mothers identified 62.4% of important needs as unmet. The five most frequently reported important unmet needs were (1 financial support; (2 break from responsibilities; (3 understanding of other after-school program children; (4 rest/sleep; (5 help remaining hopeful about the future. Most coping strategies (81% were identified as helpful. Additionally, both coping strategies and support needs served as predictors for maternal stress. Maternal stress scores decreased by .402 points for each percent increase in helpful coping strategy, and stress scores increased by .529 points with each percent increase in unmet needs. Given large variation in questionnaire responses across participants and studies, utilization of user-friendly questionnaires, such as the PSI-SF, CHIP, and FNQ, is advocated to determine the evolving important needs unique to each family over the child’s lifetime as well as guide prioritization of care, compilation of resources, and referrals for additional services.

Adaptive sampling strategies with high-throughput molecular dynamics

Science.gov (United States)

Clementi, Cecilia

Despite recent significant hardware and software developments, the complete thermodynamic and kinetic characterization of large macromolecular complexes by molecular simulations still presents significant challenges. The high dimensionality of these systems and the complexity of the associated potential energy surfaces (creating multiple metastable regions connected by high free energy barriers) does not usually allow to adequately sample the relevant regions of their configurational space by means of a single, long Molecular Dynamics (MD) trajectory. Several different approaches have been proposed to tackle this sampling problem. We focus on the development of ensemble simulation strategies, where data from a large number of weakly coupled simulations are integrated to explore the configurational landscape of a complex system more efficiently. Ensemble methods are of increasing interest as the hardware roadmap is now mostly based on increasing core counts, rather than clock speeds. The main challenge in the development of an ensemble approach for efficient sampling is in the design of strategies to adaptively distribute the trajectories over the relevant regions of the systems' configurational space, without using any a priori information on the system global properties. We will discuss the definition of smart adaptive sampling approaches that can redirect computational resources towards unexplored yet relevant regions. Our approaches are based on new developments in dimensionality reduction for high dimensional dynamical systems, and optimal redistribution of resources. NSF CHE-1152344, NSF CHE-1265929, Welch Foundation C-1570.

Breastfeeding promotion and support strategies based on Paulo Freire's epistemological categories

Directory of Open Access Journals (Sweden)

Francisca Márcia Pereira Linhares

2013-04-01

Full Text Available OBJECTIVE: This study identified strategies for promoting breastfeeding involving pregnant women, breastfeeding women and actors of the social support network for the breastfeeding process. METHODS: This qualitative study was guided by action research and the focal group technique to collect data. Focal Group 1 consisted of four pregnant and six breastfeeding women; Focal Group 2 consisted of six family members; and Focal Group 3 consisted of thirteen health professionals. The focal groups were guided by the following questions: What breastfeeding promotion and support actions should be done? How should they be performed? Who should perform them? The conversation sunder went thematic content analysis and were interpreted in the light of Paulo Freire's theoretical constructs: dialogue, ethics and problematization. RESULTS: Four themes were emerged from the conversations: dialogue-based educational actions involving the social support network during the vital cycle; educational actions in schools; educational actions in the media; ongoing counseling at Family Health Units. CONCLUSION: The constructed strategies were centered on dialogue and active listening. Both should be present during the entire vital cycle and in the Family Health Strategy, and involve all actors of the social support network. These strategies may disrupt the unidirectional transmission of the educational practices that promote breastfeeding.

Assessment of sampling strategies for estimation of site mean concentrations of stormwater pollutants.

Science.gov (United States)

McCarthy, David T; Zhang, Kefeng; Westerlund, Camilla; Viklander, Maria; Bertrand-Krajewski, Jean-Luc; Fletcher, Tim D; Deletic, Ana

2018-02-01

The estimation of stormwater pollutant concentrations is a primary requirement of integrated urban water management. In order to determine effective sampling strategies for estimating pollutant concentrations, data from extensive field measurements at seven different catchments was used. At all sites, 1-min resolution continuous flow measurements, as well as flow-weighted samples, were taken and analysed for total suspend solids (TSS), total nitrogen (TN) and Escherichia coli (E. coli). For each of these parameters, the data was used to calculate the Event Mean Concentrations (EMCs) for each event. The measured Site Mean Concentrations (SMCs) were taken as the volume-weighted average of these EMCs for each parameter, at each site. 17 different sampling strategies, including random and fixed strategies were tested to estimate SMCs, which were compared with the measured SMCs. The ratios of estimated/measured SMCs were further analysed to determine the most effective sampling strategies. Results indicate that the random sampling strategies were the most promising method in reproducing SMCs for TSS and TN, while some fixed sampling strategies were better for estimating the SMC of E. coli. The differences in taking one, two or three random samples were small (up to 20% for TSS, and 10% for TN and E. coli), indicating that there is little benefit in investing in collection of more than one sample per event if attempting to estimate the SMC through monitoring of multiple events. It was estimated that an average of 27 events across the studied catchments are needed for characterising SMCs of TSS with a 90% confidence interval (CI) width of 1.0, followed by E.coli (average 12 events) and TN (average 11 events). The coefficient of variation of pollutant concentrations was linearly and significantly correlated to the 90% confidence interval ratio of the estimated/measured SMCs (R 2  = 0.49; P sampling frequency needed to accurately estimate SMCs of pollutants. Crown

Mission Planning and Decision Support for Underwater Glider Networks: A Sampling on-Demand Approach.

Science.gov (United States)

Ferri, Gabriele; Cococcioni, Marco; Alvarez, Alberto

2015-12-26

This paper describes an optimal sampling approach to support glider fleet operators and marine scientists during the complex task of planning the missions of fleets of underwater gliders. Optimal sampling, which has gained considerable attention in the last decade, consists in planning the paths of gliders to minimize a specific criterion pertinent to the phenomenon under investigation. Different criteria (e.g., A, G, or E optimality), used in geosciences to obtain an optimum design, lead to different sampling strategies. In particular, the A criterion produces paths for the gliders that minimize the overall level of uncertainty over the area of interest. However, there are commonly operative situations in which the marine scientists may prefer not to minimize the overall uncertainty of a certain area, but instead they may be interested in achieving an acceptable uncertainty sufficient for the scientific or operational needs of the mission. We propose and discuss here an approach named sampling on-demand that explicitly addresses this need. In our approach the user provides an objective map, setting both the amount and the geographic distribution of the uncertainty to be achieved after assimilating the information gathered by the fleet. A novel optimality criterion, called A η , is proposed and the resulting minimization problem is solved by using a Simulated Annealing based optimizer that takes into account the constraints imposed by the glider navigation features, the desired geometry of the paths and the problems of reachability caused by ocean currents. This planning strategy has been implemented in a Matlab toolbox called SoDDS (Sampling on-Demand and Decision Support). The tool is able to automatically download the ocean fields data from MyOcean repository and also provides graphical user interfaces to ease the input process of mission parameters and targets. The results obtained by running SoDDS on three different scenarios are provided and show that So

Mission Planning and Decision Support for Underwater Glider Networks: A Sampling on-Demand Approach

Directory of Open Access Journals (Sweden)

Gabriele Ferri

2015-12-01

Full Text Available This paper describes an optimal sampling approach to support glider fleet operators and marine scientists during the complex task of planning the missions of fleets of underwater gliders. Optimal sampling, which has gained considerable attention in the last decade, consists in planning the paths of gliders to minimize a specific criterion pertinent to the phenomenon under investigation. Different criteria (e.g., A, G, or E optimality, used in geosciences to obtain an optimum design, lead to different sampling strategies. In particular, the A criterion produces paths for the gliders that minimize the overall level of uncertainty over the area of interest. However, there are commonly operative situations in which the marine scientists may prefer not to minimize the overall uncertainty of a certain area, but instead they may be interested in achieving an acceptable uncertainty sufficient for the scientific or operational needs of the mission. We propose and discuss here an approach named sampling on-demand that explicitly addresses this need. In our approach the user provides an objective map, setting both the amount and the geographic distribution of the uncertainty to be achieved after assimilating the information gathered by the fleet. A novel optimality criterion, called A η , is proposed and the resulting minimization problem is solved by using a Simulated Annealing based optimizer that takes into account the constraints imposed by the glider navigation features, the desired geometry of the paths and the problems of reachability caused by ocean currents. This planning strategy has been implemented in a Matlab toolbox called SoDDS (Sampling on-Demand and Decision Support. The tool is able to automatically download the ocean fields data from MyOcean repository and also provides graphical user interfaces to ease the input process of mission parameters and targets. The results obtained by running SoDDS on three different scenarios are provided

Mission Planning and Decision Support for Underwater Glider Networks: A Sampling on-Demand Approach

Science.gov (United States)

Ferri, Gabriele; Cococcioni, Marco; Alvarez, Alberto

2015-01-01

This paper describes an optimal sampling approach to support glider fleet operators and marine scientists during the complex task of planning the missions of fleets of underwater gliders. Optimal sampling, which has gained considerable attention in the last decade, consists in planning the paths of gliders to minimize a specific criterion pertinent to the phenomenon under investigation. Different criteria (e.g., A, G, or E optimality), used in geosciences to obtain an optimum design, lead to different sampling strategies. In particular, the A criterion produces paths for the gliders that minimize the overall level of uncertainty over the area of interest. However, there are commonly operative situations in which the marine scientists may prefer not to minimize the overall uncertainty of a certain area, but instead they may be interested in achieving an acceptable uncertainty sufficient for the scientific or operational needs of the mission. We propose and discuss here an approach named sampling on-demand that explicitly addresses this need. In our approach the user provides an objective map, setting both the amount and the geographic distribution of the uncertainty to be achieved after assimilating the information gathered by the fleet. A novel optimality criterion, called Aη, is proposed and the resulting minimization problem is solved by using a Simulated Annealing based optimizer that takes into account the constraints imposed by the glider navigation features, the desired geometry of the paths and the problems of reachability caused by ocean currents. This planning strategy has been implemented in a Matlab toolbox called SoDDS (Sampling on-Demand and Decision Support). The tool is able to automatically download the ocean fields data from MyOcean repository and also provides graphical user interfaces to ease the input process of mission parameters and targets. The results obtained by running SoDDS on three different scenarios are provided and show that So

The Effect of a Course Management System (CMS)-Supported Strategy Instruction on EFL Reading Comprehension and Strategy Use

Science.gov (United States)

Tsai, Yea-Ru; Talley, Paul C.

2014-01-01

This paper reports on the effect of a Moodle-supported strategy instruction on both reading comprehension and strategy use among EFL (English as a Foreign Language) students. Specific reading strategy training was first integrated into a Moodle system, which included reading exercises on problem identification, monitoring comprehension,…

Supporting Knowledge Mobilization and Research Impact Strategies in Grant Applications

Science.gov (United States)

Phipps, David; Jensen, Krista E.; Johnny, Michael; Poetz, Anneliese

2016-01-01

Each application to the National Science Foundation (NSF) must contain a Broader Impact (BI) strategy. Similarly, grant applications for most research funders in Canada and the UK require strategies to support the translation of research into impacts on society; however, the guidance provided to researchers is too general to inform the specific…

Mendelian breeding units versus standard sampling strategies: mitochondrial DNA variation in southwest Sardinia

Directory of Open Access Journals (Sweden)

Daria Sanna

2011-01-01

Full Text Available We report a sampling strategy based on Mendelian Breeding Units (MBUs, representing an interbreeding group of individuals sharing a common gene pool. The identification of MBUs is crucial for case-control experimental design in association studies. The aim of this work was to evaluate the possible existence of bias in terms of genetic variability and haplogroup frequencies in the MBU sample, due to severe sample selection. In order to reach this goal, the MBU sampling strategy was compared to a standard selection of individuals according to their surname and place of birth. We analysed mitochondrial DNA variation (first hypervariable segment and coding region in unrelated healthy subjects from two different areas of Sardinia: the area around the town of Cabras and the western Campidano area. No statistically significant differences were observed when the two sampling methods were compared, indicating that the stringent sample selection needed to establish a MBU does not alter original genetic variability and haplogroup distribution. Therefore, the MBU sampling strategy can be considered a useful tool in association studies of complex traits.

Second Chance Education: Barriers, Supports and Engagement Strategies

Science.gov (United States)

Savelsberg, Harry; Pignata, Silvia; Weckert, Pauline

2017-01-01

Second chance education programs are now a well-established presence in institutions seeking to provide access and equity pathways for socio-economically disadvantaged groups. This paper focusses on the strategies used to support positive engagement in second chance equity programs, drawing upon evaluation research data from four TAFE sponsored…

Adaptive sampling program support for expedited site characterization

International Nuclear Information System (INIS)

Johnson, R.

1993-01-01

Expedited site characterizations offer substantial savings in time and money when assessing hazardous waste sites. Key to some of these savings is the ability to adapt a sampling program to the ''real-time'' data generated by an expedited site characterization. This paper presents a two-prong approach to supporting adaptive sampling programs: a specialized object-oriented database/geographical information system for data fusion, management and display; and combined Bayesian/geostatistical methods for contamination extent estimation and sample location selection

Simulation as a learning strategy: supporting undergraduate nursing students with disabilities.

Science.gov (United States)

Azzopardi, Toni; Johnson, Amanda; Phillips, Kirrilee; Dickson, Cathy; Hengstberger-Sims, Cecily; Goldsmith, Mary; Allan, Trevor

2014-02-01

To promote simulation as a learning strategy to support undergraduate nursing students with disabilities. Supporting undergraduate nursing students with disabilities has gained further momentum because of amendments to the Disability Discrimination Act in 2009. Providers of higher education must now ensure proactive steps to prevent discrimination against students with a disability are implemented to assist in course progression. Simulation allows for the impact of a student's disability to be assessed and informs the determination of reasonable adjustments to be implemented. Further suitable adjustments can then be determined in a safe environment and evaluated prior to scheduled placement. Auditing in this manner, offers a risk management strategy for all while maintaining the academic integrity of the program. Discursive. Low, medium and high fidelity simulation activities critically analysed and their application to support undergraduate nursing students with disabilities assessed. With advancing technology and new pedagogical approaches simulation as a learning strategy can play a significant role. In this role, simulation supports undergraduate nursing students with disabilities to meet course requirements, while offering higher education providers an important risk management strategy. The discussion recommends simulation is used to inform the determination of reasonable adjustments for undergraduate nursing students with disabilities as an effective, contemporary curriculum practice. Adoption of simulation, in this way, will meet three imperatives: comply with current legislative requirements, embrace advances in learning technologies and embed one of the six principles of inclusive curriculum. Achieving these imperatives is likely to increase accessibility for all students and offer students with a disability a supportive learning experience. Provides capacity to systematically assess, monitor, evaluate and support students with a disability. The students

Sampling strategies for indoor radon investigations

International Nuclear Information System (INIS)

Prichard, H.M.

1983-01-01

Recent investigations prompted by concern about the environmental effects of residential energy conservation have produced many accounts of indoor radon concentrations far above background levels. In many instances time-normalized annual exposures exceeded the 4 WLM per year standard currently used for uranium mining. Further investigations of indoor radon exposures are necessary to judge the extent of the problem and to estimate the practicality of health effects studies. A number of trends can be discerned as more indoor surveys are reported. It is becoming increasingly clear that local geological factors play a major, if not dominant role in determining the distribution of indoor radon concentrations in a given area. Within a giving locale, indoor radon concentrations tend to be log-normally distributed, and sample means differ markedly from one region to another. The appreciation of geological factors and the general log-normality of radon distributions will improve the accuracy of population dose estimates and facilitate the design of preliminary health effects studies. The relative merits of grab samples, short and long term integrated samples, and more complicated dose assessment strategies are discussed in the context of several types of epidemiological investigations. A new passive radon sampler with a 24 hour integration time is described and evaluated as a tool for pilot investigations

Improved sample size determination for attributes and variables sampling

International Nuclear Information System (INIS)

Stirpe, D.; Picard, R.R.

1985-01-01

Earlier INMM papers have addressed the attributes/variables problem and, under conservative/limiting approximations, have reported analytical solutions for the attributes and variables sample sizes. Through computer simulation of this problem, we have calculated attributes and variables sample sizes as a function of falsification, measurement uncertainties, and required detection probability without using approximations. Using realistic assumptions for uncertainty parameters of measurement, the simulation results support the conclusions: (1) previously used conservative approximations can be expensive because they lead to larger sample sizes than needed; and (2) the optimal verification strategy, as well as the falsification strategy, are highly dependent on the underlying uncertainty parameters of the measurement instruments. 1 ref., 3 figs

Understanding Challenges, Strategies, and the Role of Support Networks in Medication Self-management Among Patients With Type 2 Diabetes.

Science.gov (United States)

Bernhard, Gerda; Ose, Dominik; Baudendistel, Ines; Seidling, Hanna M; Stützle, Marion; Szecsenyi, Joachim; Wensing, Michel; Mahler, Cornelia

2017-04-01

Purpose The purpose of this qualitative study was to investigate the challenges and strategies of patients with type 2 diabetes mellitus (T2DM) regarding daily management of their medication regimen focusing on the role of their support networks. Methods A purposeful sample of 25 patients with T2DM was recruited from local self-help groups, general practitioner practices, and a university hospital in southwestern Germany. Four semi-structured focus groups were conducted to identify the challenges patients experienced, the strategies they used, and their collaboration with support networks to assist them in self-managing their medication regimen. Sessions were audio- and video-recorded, fully transcribed, and subjected to computer-aided qualitative content analysis, guided by the Self- and Family Management Framework (SFMF). Results Patients with T2DM experienced numerous challenges affecting medication self-management arising from their personal situation, health status and resources, characteristics of their regimen, and how health care is currently organized. Patients' self-initiated strategies included activating health care, community, social, and online resources; taking ownership of medication-related needs; and integrating medication-taking into daily life. Patients drew on self-help groups, family, and friends to discuss concerns regarding medication safety and receive experience-based information and advice for navigating within the health care system as well as practical hands-on support with daily medication self-management. Conclusions Understanding the challenges and building on strategies patients with T2DM devised help diabetes educators to better address patients' needs and priorities and guide patient-centered interventions to support patients' self-management activities. Community and social support networks operating in patients' lives need to be engaged in the self-management support.

The Impact of Acculturation Strategy and Social Supports on Acculturative Stress and Academic Performance among Hispanic/Latino/a College Students

Science.gov (United States)

Luciano, David

2012-01-01

This study examined the relationship between Acculturation Strategy and Social Supports on Acculturative Stress and Academic Performance Among Hispanic/Latino/a College students. The sample of approximately 522 students was recruited at the City College of The City University of New York. Various statistical methods, including one way ANOVAS,…

Chapter 2: Sampling strategies in forest hydrology and biogeochemistry

Science.gov (United States)

Roger C. Bales; Martha H. Conklin; Branko Kerkez; Steven Glaser; Jan W. Hopmans; Carolyn T. Hunsaker; Matt Meadows; Peter C. Hartsough

2011-01-01

Many aspects of forest hydrology have been based on accurate but not necessarily spatially representative measurements, reflecting the measurement capabilities that were traditionally available. Two developments are bringing about fundamental changes in sampling strategies in forest hydrology and biogeochemistry: (a) technical advances in measurement capability, as is...

Sampling strategy to develop a primary core collection of apple ...

African Journals Online (AJOL)

PRECIOUS

2010-01-11

Jan 11, 2010 ... Physiology and Molecular Biology for Fruit, Tree, Beijing 100193, China. ... analyzed on genetic diversity to ensure their represen- .... strategy, cluster and random sampling. .... on isozyme data―A simulation study, Theor.

Release Storage and Disposal Program Product Sampling Support

International Nuclear Information System (INIS)

CALMUS, R.B.

2000-01-01

This document includes recommended capabilities and/or services to support transport, analysis, and disposition of Immobilized High-Level and Low-Activity Waste samples as requested by the US DOE-Office of River Protection (DOE-ORP) as specified in the Privatization Contract between DOE-ORP and BNFL Inc. In addition, an approved implementation path forward is presented which includes use of existing Hanford Site services to provide the required support capabilities

Authentic Leadership Strategies in Support of Mentoring Processes

Science.gov (United States)

Shapira-Lishchinsky, Orly; Levy-Gazenfrantz, Tania

2015-01-01

The aim of the study was to determine whether teacher-mentees perceive their mentors as authentic leaders and if so, how these perceptions affected their leadership strategies. The sample included 60 Israeli teacher-mentees from different school levels and different sectors, who volunteered to participate in the study. Semi-structured interviews…

Support vector machine incremental learning triggered by wrongly predicted samples

Science.gov (United States)

Tang, Ting-long; Guan, Qiu; Wu, Yi-rong

2018-05-01

According to the classic Karush-Kuhn-Tucker (KKT) theorem, at every step of incremental support vector machine (SVM) learning, the newly adding sample which violates the KKT conditions will be a new support vector (SV) and migrate the old samples between SV set and non-support vector (NSV) set, and at the same time the learning model should be updated based on the SVs. However, it is not exactly clear at this moment that which of the old samples would change between SVs and NSVs. Additionally, the learning model will be unnecessarily updated, which will not greatly increase its accuracy but decrease the training speed. Therefore, how to choose the new SVs from old sets during the incremental stages and when to process incremental steps will greatly influence the accuracy and efficiency of incremental SVM learning. In this work, a new algorithm is proposed to select candidate SVs and use the wrongly predicted sample to trigger the incremental processing simultaneously. Experimental results show that the proposed algorithm can achieve good performance with high efficiency, high speed and good accuracy.

How to Handle Speciose Clades? Mass Taxon-Sampling as a Strategy towards Illuminating the Natural History of Campanula (Campanuloideae)

Science.gov (United States)

Mansion, Guilhem; Parolly, Gerald; Crowl, Andrew A.; Mavrodiev, Evgeny; Cellinese, Nico; Oganesian, Marine; Fraunhofer, Katharina; Kamari, Georgia; Phitos, Dimitrios; Haberle, Rosemarie; Akaydin, Galip; Ikinci, Nursel; Raus, Thomas; Borsch, Thomas

2012-01-01

Background Speciose clades usually harbor species with a broad spectrum of adaptive strategies and complex distribution patterns, and thus constitute ideal systems to disentangle biotic and abiotic causes underlying species diversification. The delimitation of such study systems to test evolutionary hypotheses is difficult because they often rely on artificial genus concepts as starting points. One of the most prominent examples is the bellflower genus Campanula with some 420 species, but up to 600 species when including all lineages to which Campanula is paraphyletic. We generated a large alignment of petD group II intron sequences to include more than 70% of described species as a reference. By comparison with partial data sets we could then assess the impact of selective taxon sampling strategies on phylogenetic reconstruction and subsequent evolutionary conclusions. Methodology/Principal Findings Phylogenetic analyses based on maximum parsimony (PAUP, PRAP), Bayesian inference (MrBayes), and maximum likelihood (RAxML) were first carried out on the large reference data set (D680). Parameters including tree topology, branch support, and age estimates, were then compared to those obtained from smaller data sets resulting from “classification-guided” (D088) and “phylogeny-guided sampling” (D101). Analyses of D088 failed to fully recover the phylogenetic diversity in Campanula, whereas D101 inferred significantly different branch support and age estimates. Conclusions/Significance A short genomic region with high phylogenetic utility allowed us to easily generate a comprehensive phylogenetic framework for the speciose Campanula clade. Our approach recovered 17 well-supported and circumscribed sub-lineages. Knowing these will be instrumental for developing more specific evolutionary hypotheses and guide future research, we highlight the predictive value of a mass taxon-sampling strategy as a first essential step towards illuminating the detailed evolutionary

Sampling strategy for a large scale indoor radiation survey - a pilot project

International Nuclear Information System (INIS)

Strand, T.; Stranden, E.

1986-01-01

Optimisation of a stratified random sampling strategy for large scale indoor radiation surveys is discussed. It is based on the results from a small scale pilot project where variances in dose rates within different categories of houses were assessed. By selecting a predetermined precision level for the mean dose rate in a given region, the number of measurements needed can be optimised. The results of a pilot project in Norway are presented together with the development of the final sampling strategy for a planned large scale survey. (author)

Support for Food and Beverage Worksite Wellness Strategies and Sugar-Sweetened Beverage Intake Among Employed U.S. Adults.

Science.gov (United States)

Lee-Kwan, Seung Hee; Pan, Liping; Kimmons, Joel; Foltz, Jennifer; Park, Sohyun

2017-03-01

Sugar-sweetened beverage (SSB) consumption is high among U.S. adults and is associated with obesity. Given that more than 100 million Americans consume food or beverages at work daily, the worksite may be a venue for interventions to reduce SSB consumption. However, the level of support for these interventions is unknown. We examined associations between workday SSB intake and employees' support for worksite wellness strategies (WWSs). We conducted a cross-sectional study using data from Web-based annual surveys that gather information on health-related attitudes and behaviors. Study setting was the United States. A total of 1924 employed adults (≥18 years) selected using probability-based sampling. The self-reported independent variable was workday SSB intake (0, food/drink, (3) available healthy options, and (4) less available SSB. Multivariable logistic regression was used to control for sociodemographic variables, employee size, and availability of cafeteria/vending machine. About half of employees supported accessible free water (54%), affordable healthy food/drink (49%), and available healthy options (46%), but only 28% supported less available SSB. Compared with non-SSB consumers, daily SSB consumers were significantly less supportive of accessible free water (adjusted odds ratio, .67; p < .05) or less available SSB (odds ratio, .49; p < .05). Almost half of employees supported increasing healthy options within worksites, although daily workday SSB consumers were less supportive of certain strategies. Lack of support could be a potential barrier to the successful implementation of certain worksite interventions.

Recruitment of hard-to-reach population subgroups via adaptations of the snowball sampling strategy.

Science.gov (United States)

Sadler, Georgia Robins; Lee, Hau-Chen; Lim, Rod Seung-Hwan; Fullerton, Judith

2010-09-01

Nurse researchers and educators often engage in outreach to narrowly defined populations. This article offers examples of how variations on the snowball sampling recruitment strategy can be applied in the creation of culturally appropriate, community-based information dissemination efforts related to recruitment to health education programs and research studies. Examples from the primary author's program of research are provided to demonstrate how adaptations of snowball sampling can be used effectively in the recruitment of members of traditionally underserved or vulnerable populations. The adaptation of snowball sampling techniques, as described in this article, helped the authors to gain access to each of the more-vulnerable population groups of interest. The use of culturally sensitive recruitment strategies is both appropriate and effective in enlisting the involvement of members of vulnerable populations. Adaptations of snowball sampling strategies should be considered when recruiting participants for education programs or for research studies when the recruitment of a population-based sample is not essential.

A Mobile Health Strategy to Support Adherence to Antiretroviral Preexposure Prophylaxis.

Science.gov (United States)

Fuchs, Jonathan D; Stojanovski, Kristefer; Vittinghoff, Eric; McMahan, Vanessa M; Hosek, Sybill G; Amico, K Rivet; Kouyate, Aminta; Gilmore, Hailey J; Buchbinder, Susan P; Lester, Richard T; Grant, Robert M; Liu, Albert Y

2018-03-01

Preexposure prophylaxis is a highly protective HIV prevention strategy, yet nonadherence can significantly reduce its effectiveness. We conducted a mixed methods evaluation of a mobile health intervention (iText) that utilized weekly bidirectional text or e-mail support messages to encourage preexposure prophylaxis (PrEP) adherence among participants in the multi-site iPrEx open-label extension study. A convenience sample of PrEP users from the San Francisco and Chicago sites participated in a 12-week pilot study. Fifty-six men who have sex with men were enrolled; a quarter of them were less than 30 years of age, 13% were black/African American, 11% were Latino, and most (88%) completed some college. Two-thirds opted for text message delivery. Of the 667 messages sent, only 1 individual requested support; initial nonresponse was observed in 22% and was higher among e-mail compared to text message recipients. Poststudy, a majority of participants would recommend the intervention to others, especially during PrEP initiation. Moreover, younger participants and men of color were more likely to report that they would use the iText strategy if it were available to them. Several participants commented that while they were aware that the messages were automated, they felt supported and encouraged that "someone was always there." Study staff reported that the intervention is feasible to administer and can be incorporated readily into clinic flow. A pre-post intervention regression discontinuity analysis using clinic-based pill counts showed a 50% reduction in missed doses [95% confidence interval (CI) 16-71; p = 0.008] and 77% (95% CI 33-92; p = 0.007) when comparing pill counts at quarterly visits just before and after iText enrollment. A mobile health intervention using weekly bidirectional messaging was highly acceptable and demonstrated promising effects on PrEP adherence warranting further evaluation for efficacy in a randomized controlled trial.

Sampling strategies for the analysis of reactive low-molecular weight compounds in air

NARCIS (Netherlands)

Henneken, H.

2006-01-01

Within this thesis, new sampling and analysis strategies for the determination of airborne workplace contaminants have been developed. Special focus has been directed towards the development of air sampling methods that involve diffusive sampling. In an introductory overview, the current

NICU nurse educators: what evidence supports your teaching strategies?

Science.gov (United States)

Pilcher, Jobeth

2013-01-01

One of our roles as nurse educators is to teach best practices related to patient care. However, have you ever stopped to think about what evidence supports your teaching strategies? Just as our patients deserve care that is based on the best available evidence, our learners also deserve education that is based on evidence.1-3 With so many advances in knowledge, technology, and even life itself, it is interesting that education has changed very little over the past 100 years. A study among 946 nurse educators documented that most teach the way they were taught.4 In addition, even after learning new strategies, educators often continue teaching in the manner they are most comfortable. However, this trend is beginning to change. Nurse educators are becoming increasingly aware of and willing to try new and innovative teaching strategies. Educators are also seeking out evidence-based teaching strategies and are becoming more involved in nursing education research.

Capturing Business Strategy and Value in Enterprise Architecture to Support Portfolio Valuation

NARCIS (Netherlands)

Iacob, Maria Eugenia; Quartel, Dick; Jonkers, H.

2012-01-01

This paper investigates and enhances the suitability of the Archi Mate enterprise architecture modeling language to support the modeling of business strategy concepts and architecture-based approaches to IT portfolio valuation. It gives an overview of existing strategy and valuation concepts and

A Geostatistical Approach to Indoor Surface Sampling Strategies

DEFF Research Database (Denmark)

Schneider, Thomas; Petersen, Ole Holm; Nielsen, Allan Aasbjerg

1990-01-01

Particulate surface contamination is of concern in production industries such as food processing, aerospace, electronics and semiconductor manufacturing. There is also an increased awareness that surface contamination should be monitored in industrial hygiene surveys. A conceptual and theoretical...... framework for designing sampling strategies is thus developed. The distribution and spatial correlation of surface contamination can be characterized using concepts from geostatistical science, where spatial applications of statistics is most developed. The theory is summarized and particulate surface...... contamination, sampled from small areas on a table, have been used to illustrate the method. First, the spatial correlation is modelled and the parameters estimated from the data. Next, it is shown how the contamination at positions not measured can be estimated with kriging, a minimum mean square error method...

Social support, coping strategies and their correlations with older adults' relocation adjustments after natural disaster.

Science.gov (United States)

Chao, Shiau-Fang

2017-06-01

The present study examines the associations among social support, coping strategies and relocation adjustment outcomes, including community cohesion, residential satisfaction and depressive symptoms, for older persons in Taiwan displaced by Typhoon Morakot. This study enrolled 372 adults aged 60 years or older who were relocated to permanent houses after Typhoon Morakot destroyed their homes on 8 August 2009. A path analysis simultaneously examined the hypothesized links among social support, coping strategies and relocation adjustment outcomes. The relationships between coping strategies and relocation outcomes varied. Problem-focused and support-seeking coping were positively related to perceived community cohesion, whereas emotion-focused coping was associated with a high number of depressive symptoms. Social support was positively related to residential satisfaction. Additionally, social support was also indirectly related to increased community cohesion and residential satisfaction through its positive relationship with support-seeking and problem-focused coping. More interventions should be implemented to enhance support within informal networks and a sense of belonging to the new resident community, thereby promoting more active coping strategies, enhancing the effectiveness of coping efforts and maximizing positive adjustment outcomes. Geriatr Gerontol Int 2017; 17: 1006-1014. © 2016 Japan Geriatrics Society.

Impact of sampling strategy on stream load estimates in till landscape of the Midwest

Science.gov (United States)

Vidon, P.; Hubbard, L.E.; Soyeux, E.

2009-01-01

Accurately estimating various solute loads in streams during storms is critical to accurately determine maximum daily loads for regulatory purposes. This study investigates the impact of sampling strategy on solute load estimates in streams in the US Midwest. Three different solute types (nitrate, magnesium, and dissolved organic carbon (DOC)) and three sampling strategies are assessed. Regardless of the method, the average error on nitrate loads is higher than for magnesium or DOC loads, and all three methods generally underestimate DOC loads and overestimate magnesium loads. Increasing sampling frequency only slightly improves the accuracy of solute load estimates but generally improves the precision of load calculations. This type of investigation is critical for water management and environmental assessment so error on solute load calculations can be taken into account by landscape managers, and sampling strategies optimized as a function of monitoring objectives. ?? 2008 Springer Science+Business Media B.V.

Supporting Classroom Transitions between Daily Routines: Strategies and Tips

Science.gov (United States)

Banerjee, Rashida; Horn, Eva

2013-01-01

The purpose of this article is to provide tools for preschool professionals to plan for transitions between daily routines, to identify challenging transitions during the day, and to offer strategies to support transitions in classrooms to prevent challenging behaviors from occurring due to frequent changes. Specifically, the authors answer three…

Memory support strategies and bundles: A pathway to improving cognitive therapy for depression?

Science.gov (United States)

Dong, Lu; Lee, Jason Y; Harvey, Allison G

2017-03-01

Therapist use of memory support (MS) alongside treatment-as-usual, with the goal of enhancing patient recall of treatment contents, has been of recent interest as a novel pathway to improve treatment outcome. The memory support intervention (MSI) involves treatment providers' using 8 specific MS strategies to promote patient memory for treatment. The present study examines to what extent therapist use of MS strategies and bundles improves patient recall of treatment contents and treatment outcome. The data were drawn from a pilot RCT reported elsewhere. Participants were 48 adults (mean age = 44.27 years, 29 females) with major depressive disorder (MDD), randomized to receive 14 sessions of either CT + Memory Support (n = 25) or CT-as-usual (n = 23). Therapist use of MS was coded using the Memory Support Rating Scale. Patient memory and treatment outcomes were assessed at baseline, midtreatment (patient recall only), posttreatment, and 6-month follow-up. Participants in CT + Memory Support received significantly higher amount of MS relative to CT-as-usual. Although not reaching statistical significance, small-to-medium effects were observed between MS strategies and patient recall in the expected direction. Although MS variables were not significantly associated with changes in continuous depressive symptoms, MS was associated with better global functioning. MS also exhibited small to medium effects on treatment response and recurrence in the expected direction but not on remission, though these effects did not reach statistical significance. These results provide initial empirical evidence supporting an active method for therapists to implement MS strategies. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Perspectives on land snails - sampling strategies for isotopic analyses

Science.gov (United States)

Kwiecien, Ola; Kalinowski, Annika; Kamp, Jessica; Pellmann, Anna

2017-04-01

Since the seminal works of Goodfriend (1992), several substantial studies confirmed a relation between the isotopic composition of land snail shells (d18O, d13C) and environmental parameters like precipitation amount, moisture source, temperature and vegetation type. This relation, however, is not straightforward and site dependent. The choice of sampling strategy (discrete or bulk sampling) and cleaning procedure (several methods can be used, but comparison of their effects in an individual shell has yet not been achieved) further complicate the shell analysis. The advantage of using snail shells as environmental archive lies in the snails' limited mobility, and therefore an intrinsic aptitude of recording local and site-specific conditions. Also, snail shells are often found at dated archaeological sites. An obvious drawback is that shell assemblages rarely make up a continuous record, and a single shell is only a snapshot of the environmental setting at a given time. Shells from archaeological sites might represent a dietary component and cooking would presumably alter the isotopic signature of aragonite material. Consequently, a proper sampling strategy is of great importance and should be adjusted to the scientific question. Here, we compare and contrast different sampling approaches using modern shells collected in Morocco, Spain and Germany. The bulk shell approach (fine-ground material) yields information on mean environmental parameters within the life span of analyzed individuals. However, despite homogenization, replicate measurements of bulk shell material returned results with a variability greater than analytical precision (up to 2‰ for d18O, and up to 1‰ for d13C), calling for caution analyzing only single individuals. Horizontal high-resolution sampling (single drill holes along growth lines) provides insights into the amplitude of seasonal variability, while vertical high-resolution sampling (multiple drill holes along the same growth line

Sample preparation strategies for food and biological samples prior to nanoparticle detection and imaging

DEFF Research Database (Denmark)

Larsen, Erik Huusfeldt; Löschner, Katrin

2014-01-01

microscopy (TEM) proved to be necessary for trouble shooting of results obtained from AFFF-LS-ICP-MS. Aqueous and enzymatic extraction strategies were tested for thorough sample preparation aiming at degrading the sample matrix and to liberate the AgNPs from chicken meat into liquid suspension. The resulting...... AFFF-ICP-MS fractograms, which corresponded to the enzymatic digests, showed a major nano-peak (about 80 % recovery of AgNPs spiked to the meat) plus new smaller peaks that eluted close to the void volume of the fractograms. Small, but significant shifts in retention time of AFFF peaks were observed...... for the meat sample extracts and the corresponding neat AgNP suspension, and rendered sizing by way of calibration with AgNPs as sizing standards inaccurate. In order to gain further insight into the sizes of the separated AgNPs, or their possible dissolved state, fractions of the AFFF eluate were collected...

Sampling strategy for estimating human exposure pathways to consumer chemicals

NARCIS (Netherlands)

Papadopoulou, Eleni; Padilla-Sanchez, Juan A.; Collins, Chris D.; Cousins, Ian T.; Covaci, Adrian; de Wit, Cynthia A.; Leonards, Pim E.G.; Voorspoels, Stefan; Thomsen, Cathrine; Harrad, Stuart; Haug, Line S.

2016-01-01

Human exposure to consumer chemicals has become a worldwide concern. In this work, a comprehensive sampling strategy is presented, to our knowledge being the first to study all relevant exposure pathways in a single cohort using multiple methods for assessment of exposure from each exposure pathway.

Dried blood spot measurement: application in tacrolimus monitoring using limited sampling strategy and abbreviated AUC estimation.

Science.gov (United States)

Cheung, Chi Yuen; van der Heijden, Jaques; Hoogtanders, Karin; Christiaans, Maarten; Liu, Yan Lun; Chan, Yiu Han; Choi, Koon Shing; van de Plas, Afke; Shek, Chi Chung; Chau, Ka Foon; Li, Chun Sang; van Hooff, Johannes; Stolk, Leo

2008-02-01

Dried blood spot (DBS) sampling and high-performance liquid chromatography tandem-mass spectrometry have been developed in monitoring tacrolimus levels. Our center favors the use of limited sampling strategy and abbreviated formula to estimate the area under concentration-time curve (AUC(0-12)). However, it is inconvenient for patients because they have to wait in the center for blood sampling. We investigated the application of DBS method in tacrolimus level monitoring using limited sampling strategy and abbreviated AUC estimation approach. Duplicate venous samples were obtained at each time point (C(0), C(2), and C(4)). To determine the stability of blood samples, one venous sample was sent to our laboratory immediately. The other duplicate venous samples, together with simultaneous fingerprick blood samples, were sent to the University of Maastricht in the Netherlands. Thirty six patients were recruited and 108 sets of blood samples were collected. There was a highly significant relationship between AUC(0-12), estimated from venous blood samples, and fingerprick blood samples (r(2) = 0.96, P AUC(0-12) strategy as drug monitoring.

Building a Culture of Support: Strategies for School Leaders

Science.gov (United States)

Caposey, PJ

2013-01-01

Written in a down-to-earth and people-first style, this book is for principals and aspiring school leaders. Caposey shares insightful advice and meaningful examples for building a healthy school culture. Learn the essential strategies that will help you transform and improve your school by embodying a service mindset and focusing on supporting the…

Statistical sampling strategies

International Nuclear Information System (INIS)

Andres, T.H.

1987-01-01

Systems assessment codes use mathematical models to simulate natural and engineered systems. Probabilistic systems assessment codes carry out multiple simulations to reveal the uncertainty in values of output variables due to uncertainty in the values of the model parameters. In this paper, methods are described for sampling sets of parameter values to be used in a probabilistic systems assessment code. Three Monte Carlo parameter selection methods are discussed: simple random sampling, Latin hypercube sampling, and sampling using two-level orthogonal arrays. Three post-selection transformations are also described: truncation, importance transformation, and discretization. Advantages and disadvantages of each method are summarized

Influence of Support Configurations on the Characteristics of Selective Laser-Melted Inconel 718

Science.gov (United States)

Nadammal, Naresh; Kromm, Arne; Saliwan-Neumann, Romeo; Farahbod, Lena; Haberland, Christoph; Portella, Pedro Dolabella

2018-03-01

Samples fabricated using two different support configurations by following identical scan strategies during selective laser melting of superalloy Inconel 718 were characterized in this study. Characterization methods included optical microscopy, electron back-scattered diffraction and x-ray diffraction residual stress measurement. For the scan strategy considered, microstructure and residual stress development in the samples were influenced by the support structures. However, crystallographic texture intensity and the texture components formed within the core part of the samples were almost independent of the support. The formation of finer grains closer to the support as well as within the columnar grain boundaries resulted in randomization and texture intensity reduction by nearly half for the sample built on a lattice support. Heat transfer rates dictated by the support configurations in addition to the scan strategy influenced the microstructure and residual stress development in selective laser-melted Inconel 718 samples.

A proposal of optimal sampling design using a modularity strategy

Science.gov (United States)

Simone, A.; Giustolisi, O.; Laucelli, D. B.

2016-08-01

In real water distribution networks (WDNs) are present thousands nodes and optimal placement of pressure and flow observations is a relevant issue for different management tasks. The planning of pressure observations in terms of spatial distribution and number is named sampling design and it was faced considering model calibration. Nowadays, the design of system monitoring is a relevant issue for water utilities e.g., in order to manage background leakages, to detect anomalies and bursts, to guarantee service quality, etc. In recent years, the optimal location of flow observations related to design of optimal district metering areas (DMAs) and leakage management purposes has been faced considering optimal network segmentation and the modularity index using a multiobjective strategy. Optimal network segmentation is the basis to identify network modules by means of optimal conceptual cuts, which are the candidate locations of closed gates or flow meters creating the DMAs. Starting from the WDN-oriented modularity index, as a metric for WDN segmentation, this paper proposes a new way to perform the sampling design, i.e., the optimal location of pressure meters, using newly developed sampling-oriented modularity index. The strategy optimizes the pressure monitoring system mainly based on network topology and weights assigned to pipes according to the specific technical tasks. A multiobjective optimization minimizes the cost of pressure meters while maximizing the sampling-oriented modularity index. The methodology is presented and discussed using the Apulian and Exnet networks.

The Impacts of Self-Presentation Strategies and Social Support on Tourism Experience

DEFF Research Database (Denmark)

Kim, Jeongmi; Tussyadiah, Iis

2012-01-01

The purpose of this study is to provide an understanding of how tourists’ self-presentation is managed on Social Networking Sites (SNS). Specifically, the study investigated the effects of SNS use on social support and tourism experience and the moderating role of the different tourists’ self......-presentation strategies. The results emphasize the importance of SNS use for tourists to seek support from their social network while traveling. The study clarifies the importance of SNS use for tourism experience, in that the more engaged tourists are in social interaction facilitated with SNS while traveling, the more...... likely they are to have a positive tourism experience. Also, it is argued that social support does not always directly result from the intense SNS use, but rather moderated by tourists’ self-presentation strategies....

Strategy of Trade-Reliable Featured Product Supporting Regional Innovation Systems

Science.gov (United States)

Riskiawan, H. Y.; Purnomo, B. H.; Abdurahman, A.; Hariono, B.; Puspitasari, T. D.

2018-01-01

Pacitan, Ponorogo, and Magetan had planned the development of featured products as contained in the Medium Term Development Plan (MTDP) until 2020. The focus of development is almost similar to featured products derived from agribusiness, food processing, handycrafts, and tourism. The geographical proximity results characteristics of natural resources and social culture have similarities, including the type of featured products, constraints, problems, and opportunities for development. Given the characteristics and the support system of some featured products contained in these three regions have a lot in common and their functional interactions involving actors from across the region, it is necessary to develop cross-jurisdictional policy. The resulting strategy should be able to support the development of Regional Innovation System (RIS). The purpose of this research is 1) Determining featured product cross-regional between Pacitan regency; Ponorogo and Magetan districts in support of RIS development; and 2) Designing a featured product development strategy using supply chain management in order to drive the local economy. Based on the results of research conducted, featured products across the region that have potentiality to be developed are: processed products of “janggelan” leather products, and woven bamboo.

Recruiting hard-to-reach United States population sub-groups via adaptations of snowball sampling strategy

Science.gov (United States)

Sadler, Georgia Robins; Lee, Hau-Chen; Seung-Hwan Lim, Rod; Fullerton, Judith

2011-01-01

Nurse researchers and educators often engage in outreach to narrowly defined populations. This article offers examples of how variations on the snowball sampling recruitment strategy can be applied in the creation of culturally appropriate, community-based information dissemination efforts related to recruitment to health education programs and research studies. Examples from the primary author’s program of research are provided to demonstrate how adaptations of snowball sampling can be effectively used in the recruitment of members of traditionally underserved or vulnerable populations. The adaptation of snowball sampling techniques, as described in this article, helped the authors to gain access to each of the more vulnerable population groups of interest. The use of culturally sensitive recruitment strategies is both appropriate and effective in enlisting the involvement of members of vulnerable populations. Adaptations of snowball sampling strategies should be considered when recruiting participants for education programs or subjects for research studies when recruitment of a population based sample is not essential. PMID:20727089

Adherence support strategies for exercise interventions in people with mild cognitive impairment and dementia: A systematic review

Directory of Open Access Journals (Sweden)

Veronika van der Wardt

2017-09-01

Full Text Available Exercise-based therapy may improve health status for people with Mild Cognitive Impairment (MCI or dementia but cannot work without adherence, which has proven difficult. This review aimed to evaluate strategies to support adherence among people with MCI or Dementia and was completed in Nottingham/UK in 2017. A narrative synthesis was used to investigate the effectiveness or usefulness of adherence support strategies. Fifteen adherence support strategies were used including theoretical underpinning (programmes based on behavior change theories, individual tailoring, worksheets and exercise booklets, goal setting, phone calls or reminders, newsletters, support to overcome exercise barriers, information, adaptation periods, individual supervision, support for clinicians, group setting, music, accelerometers/pedometers and emphasis on enjoyable activities. Music was the only strategy that was investigated in a comparative design but was found to be effective only for those who were generally interested in participating in activities. A wide range of adherence support strategies are being included in exercise interventions for people with MCI or dementia, but the evidence regarding their effectiveness is limited.

Strategies for fostering basic psychological needs support in high quality youth leadership programs.

Science.gov (United States)

Bean, Corliss; Harlow, Meghan; Kendellen, Kelsey

2017-04-01

Youth leadership programming has become an increasingly common context to foster basic psychological needs and promote youth development. The purpose of this qualitative study was to explore strategies involved in fostering youth needs support within six leadership programs. Two leaders and 30 youth participated in semi-structured interviews to better understand the strategies used to foster needs support. Findings revealed that leaders were able to foster a sense of relatedness among youth through building trusting adult-youth relationships and nurturing an inclusive environment. Maximizing choice and negotiating youth voice helped to foster youth's autonomy. Finally, creating a task-oriented climate and providing intentional opportunities for skill-building helped to foster youth's competence. Findings suggest that training for leaders is critical in understanding what, and how strategies should be employed to help foster youth needs support in leadership programming. Limitations and future directions are outlined. Copyright © 2016 Elsevier Ltd. All rights reserved.

Sampling and analyte enrichment strategies for ambient mass spectrometry.

Science.gov (United States)

Li, Xianjiang; Ma, Wen; Li, Hongmei; Ai, Wanpeng; Bai, Yu; Liu, Huwei

2018-01-01

Ambient mass spectrometry provides great convenience for fast screening, and has showed promising potential in analytical chemistry. However, its relatively low sensitivity seriously restricts its practical utility in trace compound analysis. In this review, we summarize the sampling and analyte enrichment strategies coupled with nine modes of representative ambient mass spectrometry (desorption electrospray ionization, paper vhspray ionization, wooden-tip spray ionization, probe electrospray ionization, coated blade spray ionization, direct analysis in real time, desorption corona beam ionization, dielectric barrier discharge ionization, and atmospheric-pressure solids analysis probe) that have dramatically increased the detection sensitivity. We believe that these advances will promote routine use of ambient mass spectrometry. Graphical abstract Scheme of sampling stretagies for ambient mass spectrometry.

Observing System Simulation Experiments for the assessment of temperature sampling strategies in the Mediterranean Sea

Directory of Open Access Journals (Sweden)

F. Raicich

2003-01-01

Full Text Available For the first time in the Mediterranean Sea various temperature sampling strategies are studied and compared to each other by means of the Observing System Simulation Experiment technique. Their usefulness in the framework of the Mediterranean Forecasting System (MFS is assessed by quantifying their impact in a Mediterranean General Circulation Model in numerical twin experiments via univariate data assimilation of temperature profiles in summer and winter conditions. Data assimilation is performed by means of the optimal interpolation algorithm implemented in the SOFA (System for Ocean Forecasting and Analysis code. The sampling strategies studied here include various combinations of eXpendable BathyThermograph (XBT profiles collected along Volunteer Observing Ship (VOS tracks, Airborne XBTs (AXBTs and sea surface temperatures. The actual sampling strategy adopted in the MFS Pilot Project during the Targeted Operational Period (TOP, winter-spring 2000 is also studied. The data impact is quantified by the error reduction relative to the free run. The most effective sampling strategies determine 25–40% error reduction, depending on the season, the geographic area and the depth range. A qualitative relationship can be recognized in terms of the spread of information from the data positions, between basin circulation features and spatial patterns of the error reduction fields, as a function of different spatial and seasonal characteristics of the dynamics. The largest error reductions are observed when samplings are characterized by extensive spatial coverages, as in the cases of AXBTs and the combination of XBTs and surface temperatures. The sampling strategy adopted during the TOP is characterized by little impact, as a consequence of a sampling frequency that is too low. Key words. Oceanography: general (marginal and semi-enclosed seas; numerical modelling

Observing System Simulation Experiments for the assessment of temperature sampling strategies in the Mediterranean Sea

Directory of Open Access Journals (Sweden)

F. Raicich

Full Text Available For the first time in the Mediterranean Sea various temperature sampling strategies are studied and compared to each other by means of the Observing System Simulation Experiment technique. Their usefulness in the framework of the Mediterranean Forecasting System (MFS is assessed by quantifying their impact in a Mediterranean General Circulation Model in numerical twin experiments via univariate data assimilation of temperature profiles in summer and winter conditions. Data assimilation is performed by means of the optimal interpolation algorithm implemented in the SOFA (System for Ocean Forecasting and Analysis code. The sampling strategies studied here include various combinations of eXpendable BathyThermograph (XBT profiles collected along Volunteer Observing Ship (VOS tracks, Airborne XBTs (AXBTs and sea surface temperatures. The actual sampling strategy adopted in the MFS Pilot Project during the Targeted Operational Period (TOP, winter-spring 2000 is also studied.

The data impact is quantified by the error reduction relative to the free run. The most effective sampling strategies determine 25–40% error reduction, depending on the season, the geographic area and the depth range. A qualitative relationship can be recognized in terms of the spread of information from the data positions, between basin circulation features and spatial patterns of the error reduction fields, as a function of different spatial and seasonal characteristics of the dynamics. The largest error reductions are observed when samplings are characterized by extensive spatial coverages, as in the cases of AXBTs and the combination of XBTs and surface temperatures. The sampling strategy adopted during the TOP is characterized by little impact, as a consequence of a sampling frequency that is too low.

Key words. Oceanography: general (marginal and semi-enclosed seas; numerical modelling

Mentoring K scholars: strategies to support research mentors.

Science.gov (United States)

Burnham, Ellen L; Schiro, Stephanie; Fleming, Michael

2011-06-01

The goal of this paper is to present strategies utilized to support K scholar research mentors. K scholars are generally assistant professors who are close to developing independent research programs. Of all the various types of mentees, K scholars offer the greatest challenges, as well as the greatest rewards, for research mentors. To see one's mentee achieve independent PI status and become an established investigator is one of the great joys of being a research mentor. Research mentors for K scholars, however, may not directly benefit from their mentoring relationship, neither in terms of obtaining data to support their research program or laboratory, nor in assistance with grants or scientific papers. There is a pressing need for the research community to address the workload, institutional expectations, and reward system for research mentors. The dearth of research mentors and role models in clinical translational science parallels the decreasing number of physicians choosing careers in clinical research. While there is limited empirical information on the effectiveness of mentor support mechanisms, this white paper concludes that providing mentor support is critical to expanding the available pool of mentors, as well as providing training opportunities for K scholars. © 2011 Wiley Periodicals, Inc.

The Viking X ray fluorescence experiment - Sampling strategies and laboratory simulations. [Mars soil sampling

Science.gov (United States)

Baird, A. K.; Castro, A. J.; Clark, B. C.; Toulmin, P., III; Rose, H., Jr.; Keil, K.; Gooding, J. L.

1977-01-01

Ten samples of Mars regolith material (six on Viking Lander 1 and four on Viking Lander 2) have been delivered to the X ray fluorescence spectrometers as of March 31, 1977. An additional six samples at least are planned for acquisition in the remaining Extended Mission (to January 1979) for each lander. All samples acquired are Martian fines from the near surface (less than 6-cm depth) of the landing sites except the latest on Viking Lander 1, which is fine material from the bottom of a trench dug to a depth of 25 cm. Several attempts on each lander to acquire fresh rock material (in pebble sizes) for analysis have yielded only cemented surface crustal material (duricrust). Laboratory simulation and experimentation are required both for mission planning of sampling and for interpretation of data returned from Mars. This paper is concerned with the rationale for sample site selections, surface sampler operations, and the supportive laboratory studies needed to interpret X ray results from Mars.

[Study of spatial stratified sampling strategy of Oncomelania hupensis snail survey based on plant abundance].

Science.gov (United States)

Xun-Ping, W; An, Z

2017-07-27

Objective To optimize and simplify the survey method of Oncomelania hupensis snails in marshland endemic regions of schistosomiasis, so as to improve the precision, efficiency and economy of the snail survey. Methods A snail sampling strategy (Spatial Sampling Scenario of Oncomelania based on Plant Abundance, SOPA) which took the plant abundance as auxiliary variable was explored and an experimental study in a 50 m×50 m plot in a marshland in the Poyang Lake region was performed. Firstly, the push broom surveyed data was stratified into 5 layers by the plant abundance data; then, the required numbers of optimal sampling points of each layer through Hammond McCullagh equation were calculated; thirdly, every sample point in the line with the Multiple Directional Interpolation (MDI) placement scheme was pinpointed; and finally, the comparison study among the outcomes of the spatial random sampling strategy, the traditional systematic sampling method, the spatial stratified sampling method, Sandwich spatial sampling and inference and SOPA was performed. Results The method (SOPA) proposed in this study had the minimal absolute error of 0.213 8; and the traditional systematic sampling method had the largest estimate, and the absolute error was 0.924 4. Conclusion The snail sampling strategy (SOPA) proposed in this study obtains the higher estimation accuracy than the other four methods.

Support, shape and number of replicate samples for tree foliage analysis

NARCIS (Netherlands)

Luyssaert, Sebastiaan; Mertens, Jan; Raitio, Hannu

Many fundamental features of a sampling program are determined by the heterogeneity of the object under study and the settings for the error (α), the power (β), the effect size (ES), the number of replicate samples, and sample support, which is a feature that is often overlooked. The number of

Strategies to facilitate stakeholder and regulator support for technology deployment

International Nuclear Information System (INIS)

Burford, T.D.

1997-01-01

Implementation and deployment of new and innovative environmental technologies is impossible without regulator, enduser and stakeholder support. Technologies being developed for different needs require different strategies to facilitate this endorsement. Areas addressed will include technologies developed to meet site specific cleanup needs and those developed for multiple site applications. A third area deals with using site specific technologies at previously unidentified locations. In order to expand the application of these technologies to other sites a plan to include potential site regulators and stakeholders early in the development process should be considered. The Subsurface Contaminant Focus Area has developed a Stakeholder Communication Plan. This plan, in addition to lessons learned from current technology development projects that have successfully obtained this type of support, will provide the basis for the information provided in this paper. The object of this paper is to suggest strategies that could facilitate the implementation and deployment of technologies at environmental sites by involving regulators and stakeholders at the proper time for various applications

Perceived Barriers and Support Strategies for Reducing Sodium Intake in Patients with Chronic Kidney Disease: a Qualitative Study.

Science.gov (United States)

Meuleman, Yvette; Ten Brinke, Lucia; Kwakernaak, Arjan J; Vogt, Liffert; Rotmans, Joris I; Bos, Willem Jan W; van der Boog, Paul J M; Navis, Gerjan; van Montfrans, Gert A; Hoekstra, Tiny; Dekker, Friedo W; van Dijk, Sandra

2015-08-01

Reducing sodium intake can prevent cardiovascular complications and further decline of kidney function in patients with chronic kidney disease. However, the vast majority of patients fail to reach an adequate sodium intake, and little is known about why they do not succeed. This study aims to identify perceived barriers and support strategies for reducing sodium intake among both patients with chronic kidney disease and health-care professionals. A purposive sample of 25 patients and 23 health-care professionals from 4 Dutch medical centers attended 8 focus groups. Transcripts were analyzed thematically and afterwards organized according to the phases of behavior change of self-regulation theory. Multiple themes emerged across different phases of behavior change, including the patients' lack of practical knowledge and intrinsic motivation, the maladaptive illness perceptions and refusal skills, the lack of social support and feedback regarding disease progression and sodium intake, and the availability of low-sodium foods. The results indicate the need for the implementation of support strategies that target specific needs of patients across the whole process of changing and maintaining a low-sodium diet. Special attention should be paid to supporting patients to set sodium-related goals, strengthening intrinsic motivation, providing comprehensive and practical information (e.g., about hidden salt in products), increasing social support, stimulating the self-monitoring of sodium intake and disease progression, and building a supportive patient-professional relationship that encompasses shared decision making and coaching. Moreover, global programs should be implemented to reduce sodium levels in processed foods, introduce sodium-related product labels, and increase consumer awareness.

The relations between interpersonal self-support traits and emotion regulation strategies: a longitudinal study.

Science.gov (United States)

Xia, Ling-Xiang; Gao, Xin; Wang, Qian; Hollon, Steven D

2014-08-01

Although several cross-sectional surveys have shown that certain traits such as extraversion and neuroticism are related to emotion regulation, few studies have explored the nature of this relationship. The present study tried to explore the longitudinal relation between traits and emotion regulation strategies. The Interpersonal Self-Support Scale for Middle School Students (ISSS-MSS) and the Emotion Regulation Questionnaire (ERQ) were administrated to 374 middle school students two times across a 6-month interval. A path analysis via structural equation modeling of the five interpersonal self-support traits and the two emotion regulation strategies was tested. The results showed that interpersonal independence predicted expressive suppression and cognitive reappraisal, and that interpersonal initiative also predicted reappraisal, while reappraisal predicted interpersonal flexibility and interpersonal openness 6 month later. These results support the hypotheses that some personality traits influence certain emotion regulation strategies, while other traits may be influenced by specific emotion regulation strategies. Copyright © 2014 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

Decision Strategy Research and Policy Support

International Nuclear Information System (INIS)

Hardeman, F.

2002-01-01

The objective of SCK-CEN's R and D programme on decision strategies and policy support is: (1) to investigate the decision making process, with all its relevant dimensions, in the context of radiation protection or other nuclear issues (with particular emphasis on emergency preparedness); (2) to disseminate knowledge on decision making and nuclear emergencies, including the organisation of training courses, the contribution to manuals or guidelines, the participation in working groups or discussion forums; (3) to assist the authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available; (4) to participate in and contribute to initiatives related to social sciences and their implementation into SCK-CEN; (5) to co-ordinate efforts of SCK-CEN related to medical applications of ionising radiation. Principal achievements in 2001 are described

Relative Effectiveness of Computer-Supported Jigsaw II, STAD and TAI Cooperative Learning Strategies on Performance, Attitude, and Retention of Secondary School Students in Physics

Science.gov (United States)

Gambari, Amosa Isiaka; Yusuf, Mudasiru Olalere

2017-01-01

This study investigated the relative effectiveness of computer-supported cooperative learning strategies on the performance, attitudes, and retention of secondary school students in physics. A purposive sampling technique was used to select four senior secondary schools from Minna, Nigeria. The students were allocated to one of four groups:…

A sampling strategy for estimating plot average annual fluxes of chemical elements from forest soils

NARCIS (Netherlands)

Brus, D.J.; Gruijter, de J.J.; Vries, de W.

2010-01-01

A sampling strategy for estimating spatially averaged annual element leaching fluxes from forest soils is presented and tested in three Dutch forest monitoring plots. In this method sampling locations and times (days) are selected by probability sampling. Sampling locations were selected by

Sample preparation composite and replicate strategy for assay of solid oral drug products.

Science.gov (United States)

Harrington, Brent; Nickerson, Beverly; Guo, Michele Xuemei; Barber, Marc; Giamalva, David; Lee, Carlos; Scrivens, Garry

2014-12-16

In pharmaceutical analysis, the results of drug product assay testing are used to make decisions regarding the quality, efficacy, and stability of the drug product. In order to make sound risk-based decisions concerning drug product potency, an understanding of the uncertainty of the reportable assay value is required. Utilizing the most restrictive criteria in current regulatory documentation, a maximum variability attributed to method repeatability is defined for a drug product potency assay. A sampling strategy that reduces the repeatability component of the assay variability below this predefined maximum is demonstrated. The sampling strategy consists of determining the number of dosage units (k) to be prepared in a composite sample of which there may be a number of equivalent replicate (r) sample preparations. The variability, as measured by the standard error (SE), of a potency assay consists of several sources such as sample preparation and dosage unit variability. A sampling scheme that increases the number of sample preparations (r) and/or number of dosage units (k) per sample preparation will reduce the assay variability and thus decrease the uncertainty around decisions made concerning the potency of the drug product. A maximum allowable repeatability component of the standard error (SE) for the potency assay is derived using material in current regulatory documents. A table of solutions for the number of dosage units per sample preparation (r) and number of replicate sample preparations (k) is presented for any ratio of sample preparation and dosage unit variability.

Coordinated Control Strategies for Offshore Wind Farm Integration via VSC-HVDC for System Frequency Support

DEFF Research Database (Denmark)

Li, Yujun; Xu, Zhao; Østergaard, Jacob

2017-01-01

Coordinated control strategies to provide system inertia support for main grid from offshore wind farm that is integrated through HVdc transmission is the subject matter of this paper. The strategy that seeks to provide inertia support to the main grid through simultaneous utilization of HVdc...... capacitors energy, and wind turbines (WTs) inertia without installing the remote communication of two HVdc terminals is introduced in details. Consequently, a novel strategy is proposed to improve system inertia through sequentially exerting dc capacitors energy and then WTs inertia via a cascading control...

Strategy to increase Barangan Banana production in Kabupaten Deli Serdang

Science.gov (United States)

Adhany, I.; Chalil, D.; Ginting, R.

2018-02-01

This study was conducted to analyze internal and external factors in increasing Barangan Banana production in Kabupaten Deli Serdang. Samples were determined by snowball sampling technique and purposive sampling method. Using SWOT analysis method, this study found that there were 6 internal strategic factors and 9 external strategic factors. Among that strategic factors, support for production facilities appears as the most important internal strategic factor, while the demand for Barangan Banana. as the most important external strategic factor. Based on the importance and existing condition of these strategic factors, using support for production facilities and realization of supporting facilities with farming experience are the strategies covering strength-opportunity (SO), organizing mentoring to meet the demand for Barangan Banana are the strategies covering weakness-opportunity (WO), making use of funding support and subsidies to widen the land, using tissue culture seeds and facilities and infrastructures are the strategies covering strength-threat (ST), increas the funding support to widen the land, the use of tissue culture seeds and facilities and infrastructures are the strategies covering weakness-threat (WT) are discussed and proposed to increase Barangan Banana productivity in Kabupaten Deli Serdang.

Development and Demonstration of a Method to Evaluate Bio-Sampling Strategies Using Building Simulation and Sample Planning Software

OpenAIRE

Dols, W. Stuart; Persily, Andrew K.; Morrow, Jayne B.; Matzke, Brett D.; Sego, Landon H.; Nuffer, Lisa L.; Pulsipher, Brent A.

2010-01-01

In an effort to validate and demonstrate response and recovery sampling approaches and technologies, the U.S. Department of Homeland Security (DHS), along with several other agencies, have simulated a biothreat agent release within a facility at Idaho National Laboratory (INL) on two separate occasions in the fall of 2007 and the fall of 2008. Because these events constitute only two realizations of many possible scenarios, increased understanding of sampling strategies can be obtained by vir...

Metabolomic analysis of urine samples by UHPLC-QTOF-MS: Impact of normalization strategies.

Science.gov (United States)

Gagnebin, Yoric; Tonoli, David; Lescuyer, Pierre; Ponte, Belen; de Seigneux, Sophie; Martin, Pierre-Yves; Schappler, Julie; Boccard, Julien; Rudaz, Serge

2017-02-22

Among the various biological matrices used in metabolomics, urine is a biofluid of major interest because of its non-invasive collection and its availability in large quantities. However, significant sources of variability in urine metabolomics based on UHPLC-MS are related to the analytical drift and variation of the sample concentration, thus requiring normalization. A sequential normalization strategy was developed to remove these detrimental effects, including: (i) pre-acquisition sample normalization by individual dilution factors to narrow the concentration range and to standardize the analytical conditions, (ii) post-acquisition data normalization by quality control-based robust LOESS signal correction (QC-RLSC) to correct for potential analytical drift, and (iii) post-acquisition data normalization by MS total useful signal (MSTUS) or probabilistic quotient normalization (PQN) to prevent the impact of concentration variability. This generic strategy was performed with urine samples from healthy individuals and was further implemented in the context of a clinical study to detect alterations in urine metabolomic profiles due to kidney failure. In the case of kidney failure, the relation between creatinine/osmolality and the sample concentration is modified, and relying only on these measurements for normalization could be highly detrimental. The sequential normalization strategy was demonstrated to significantly improve patient stratification by decreasing the unwanted variability and thus enhancing data quality. Copyright © 2016 Elsevier B.V. All rights reserved.

Where Does Handwriting Fit in? Strategies to Support Academic Achievement

Science.gov (United States)

Cahill, Susan M.

2009-01-01

In today's environment of high-stakes testing, handwriting is a skill that is often overlooked in order to focus on other areas of the curriculum. However, research indicates that handwriting is tied to academic achievement, especially composition and literacy skills. This article provides strategies that can be used to support students with…

Peer Support and Psychosocial Pain Management Strategies for Children with Systemic Lupus Erythematosus

Directory of Open Access Journals (Sweden)

Laura Nabors

2015-01-01

Full Text Available This paper reviews information on Systemic Lupus Erythematosus (SLE in children. Children with this chronic illness often experience pain related to their condition. They also can experience social isolation. This paper reviews psychosocial information on peer support and cognitive behavioral pain management strategies. The information presented in this paper provides new insights for health professionals assisting children and families in coping with psychological facets of this disease. Research focusing on ways by which peers and friends can support the child’s use of psychological pain management strategies will provide new information for the literature.

GIZ approaches on Low-Emission Development Strategies. The need for support from research

International Nuclear Information System (INIS)

Zymia, Bernhard

2015-01-01

First results of GIZ support on the development of Low-Emission Development Strategy (LED) in Costa Rica are promising and have motivated key ministries to integrate the climate policy into their structures. Awareness of the issue of climate change among the general public is increasing, the competencies of the National Secretariat for Climate Protection have been strengthened: its capability for strategic planning has been improved. The most important challenges still remain, like the manifold “LEDS” documents on national level, weak connection of existing development strategies, weak integration across ministries, the limited financial capacities or the fragmented international support.

Decision Strategy Research and Policy Support

Energy Technology Data Exchange (ETDEWEB)

Hardeman, F

2002-04-01

The objective of SCK-CEN's R and D programme on decision strategies and policy support is: (1) to investigate the decision making process, with all its relevant dimensions, in the context of radiation protection or other nuclear issues (with particular emphasis on emergency preparedness); (2) to disseminate knowledge on decision making and nuclear emergencies, including the organisation of training courses, the contribution to manuals or guidelines, the participation in working groups or discussion forums; (3) to assist the authorities and the industry on any topic related to radiation protection and to make expertise and infrastructure available; (4) to participate in and contribute to initiatives related to social sciences and their implementation into SCK-CEN; (5) to co-ordinate efforts of SCK-CEN related to medical applications of ionising radiation. Principal achievements in 2001 are described.

Health system strategies supporting transition to adult care.

Science.gov (United States)

Hepburn, Charlotte Moore; Cohen, Eyal; Bhawra, Jasmin; Weiser, Natalie; Hayeems, Robin Z; Guttmann, Astrid

2015-06-01

The transition from paediatric to adult care is associated with poor clinical outcomes, increased costs and low patient and family satisfaction. However, little is known about health system strategies to streamline and safeguard care for youth transitioning to adult services. Moreover, the needs of children and youth are often excluded from broader health system reform discussions, leaving this population especially vulnerable to system 'disintegration'. (1) To explore the international policy profile of paediatric-to-adult care transitions, and (2) to document policy objectives, initiatives and outcomes for jurisdictions publicly committed to addressing transition issues. An international policy scoping review of all publicly available government documents detailing transition-related strategies was completed using a web-based search. Our analysis included a comparable cohort of nine wealthy Organisation for Economic Co-operation and Development (OECD) jurisdictions with Beveridge-style healthcare systems (deemed those most likely to benefit from system-level transition strategies). Few jurisdictions address transition of care issues in either health or broader social policy documents. While many jurisdictions refer to standardised practice guidelines, a few report the intention to use powerful policy levers (including physician remuneration and non-physician investments) to facilitate the uptake of best practice. Most jurisdictions do not address the policy infrastructure required to support successful transitions, and rigorous evaluations of transition strategies are rare. Despite the well-documented risks and costs associated with a poor transition from paediatric to adult care, little policy attention has been paid to this issue. We recommend that healthcare providers engage health system planners in the design and evaluation of system-level, policy-sensitive transition strategies. Published by the BMJ Publishing Group Limited. For permission to use (where not

Coping strategies and social support needs of experienced and inexperienced nurses performing shiftwork.

Science.gov (United States)

Gifkins, Jane; Loudoun, Rebecca; Johnston, Amy

2017-12-01

The aim of this investigation was to compare perceptions of nurses exposed to short or longer term shift work and their experiences working under this type of scheduling. Shift work is a crucial component of nurses' working lives, ensuring continuous care for patients. This study fills a research gap around the personal experiences of shift working nurses and the strategies used to manage the impacts of shift work. Qualitative case study design. Constructivist methodology, including in-depth semi-structured interviews conducted in 2015, was used for the study. Iterative review and inductive analysis of transcripts from nine recently graduated nurses and twelve experienced nurses enabled identification and verification of key themes. Three main areas of difference between new and experienced nurses relating to shift work challenges in a nursing environment emerged: perceptions about the utility of working in shifts, coping strategies and social support at home and work. Most experienced nurses found shift work advantageous, especially those with dependents. Coping strategies included flexible shift arrangements in both groups. Experienced nurses detailed the importance of support from family and friends while inexperienced nurses described feeling disconnected from social supports. Experienced nurses cited a lack of support from nursing managers as problematic. Findings suggest shift selection mitigated challenges of shift work for both inexperienced and experienced nurses, indicating autonomous roster selection is critical. Similarly, social support at work from senior nurses and management and at home played an important role in nurses' coping. © 2017 John Wiley & Sons Ltd.

A cache-friendly sampling strategy for texture-based volume rendering on GPU

Directory of Open Access Journals (Sweden)

Junpeng Wang

2017-06-01

Full Text Available The texture-based volume rendering is a memory-intensive algorithm. Its performance relies heavily on the performance of the texture cache. However, most existing texture-based volume rendering methods blindly map computational resources to texture memory and result in incoherent memory access patterns, causing low cache hit rates in certain cases. The distance between samples taken by threads of an atomic scheduling unit (e.g. a warp of 32 threads in CUDA of the GPU is a crucial factor that affects the texture cache performance. Based on this fact, we present a new sampling strategy, called Warp Marching, for the ray-casting algorithm of texture-based volume rendering. The effects of different sample organizations and different thread-pixel mappings in the ray-casting algorithm are thoroughly analyzed. Also, a pipeline manner color blending approach is introduced and the power of warp-level GPU operations is leveraged to improve the efficiency of parallel executions on the GPU. In addition, the rendering performance of the Warp Marching is view-independent, and it outperforms existing empty space skipping techniques in scenarios that need to render large dynamic volumes in a low resolution image. Through a series of micro-benchmarking and real-life data experiments, we rigorously analyze our sampling strategies and demonstrate significant performance enhancements over existing sampling methods.

Strategy for thermo-gravimetric analysis of K East fuel samples

International Nuclear Information System (INIS)

Lawrence, L.A.

1997-01-01

A strategy was developed for the Thermo-Gravimetric Analysis (TGA) testing of K East fuel samples for oxidation rate determinations. Tests will first establish if there are any differences for dry air oxidation between the K West and K East fuel. These tests will be followed by moist inert gas oxidation rate measurements. The final series of tests will consider pure water vapor i.e., steam

A census-weighted, spatially-stratified household sampling strategy for urban malaria epidemiology

Directory of Open Access Journals (Sweden)

Slutsker Laurence

2008-02-01

Full Text Available Abstract Background Urban malaria is likely to become increasingly important as a consequence of the growing proportion of Africans living in cities. A novel sampling strategy was developed for urban areas to generate a sample simultaneously representative of population and inhabited environments. Such a strategy should facilitate analysis of important epidemiological relationships in this ecological context. Methods Census maps and summary data for Kisumu, Kenya, were used to create a pseudo-sampling frame using the geographic coordinates of census-sampled structures. For every enumeration area (EA designated as urban by the census (n = 535, a sample of structures equal to one-tenth the number of households was selected. In EAs designated as rural (n = 32, a geographically random sample totalling one-tenth the number of households was selected from a grid of points at 100 m intervals. The selected samples were cross-referenced to a geographic information system, and coordinates transferred to handheld global positioning units. Interviewers found the closest eligible household to the sampling point and interviewed the caregiver of a child aged Results 4,336 interviews were completed in 473 of the 567 study area EAs from June 2002 through February 2003. EAs without completed interviews were randomly distributed, and non-response was approximately 2%. Mean distance from the assigned sampling point to the completed interview was 74.6 m, and was significantly less in urban than rural EAs, even when controlling for number of households. The selected sample had significantly more children and females of childbearing age than the general population, and fewer older individuals. Conclusion This method selected a sample that was simultaneously population-representative and inclusive of important environmental variation. The use of a pseudo-sampling frame and pre-programmed handheld GPS units is more efficient and may yield a more complete sample than

Strategies to improve medication adherence in patients with schizophrenia: the role of support services

Directory of Open Access Journals (Sweden)

El-Mallakh P

2015-04-01

Full Text Available Peggy El-Mallakh, Jan FindlayCollege of Nursing, University of Kentucky, Lexington, KY, USAAbstract: The purpose of this review is to describe research over the past 10 years on the role of support services in promoting medication adherence in mental health consumers diagnosed with schizophrenia. A literature search was conducted using the terms “medication adherence,” “schizophrenia,” and “support services,” using Medline, PubMed, and CINAHL. Reference lists from published studies were also reviewed to identify additional research studies. Twenty-two articles focused on support-service intervention studies, and these were selected for review. Available support-service interventions include adherence therapy, electronic reminders via text messages and telephones, cognitive–behavioral and motivational strategies, and financial incentives. Support-service intervention strategies need to be tailored to the specific needs of mental health consumers with schizophrenia. More research is needed to investigate effective support services to enhance long-term adherence and adherence to medications for medical illnesses in this population.Keywords: schizophrenia, medication adherence, support services, therapy, interventions

Positioning a University Outreach Center: Strategies for Support and Continuation.

Science.gov (United States)

Skivington, Kristen D.

1998-01-01

Argues that a strong case can be made for supporting outreach as a value-added function in a university. Specific strategies for positioning outreach within the university by developing a power base are outlined. The case of the University of Michigan-Flint is offered as an example of this approach. Seven lessons learned in the process are noted.…

Supporting Learning from Illustrated Texts: Conceptualizing and Evaluating a Learning Strategy

Science.gov (United States)

Schlag, Sabine; Ploetzner, Rolf

2011-01-01

Texts and pictures are often combined in order to improve learning. Many students, however, have difficulty to appropriately process text-picture combinations. We have thus conceptualized a learning strategy which supports learning from illustrated texts. By inducing the processes of information selection, organization, integration, and…

Department of Defense energy policy and research: A framework to support strategy

International Nuclear Information System (INIS)

Strakos, Joshua K.; Quintanilla, Jose A.; Huscroft, Joseph R.

2016-01-01

The Department of Defense (DOD) is the major consumer of energy within the Federal government, and it has been directed to implement cost cutting measures related to energy dependence through numerous Executive Orders and Congressional legislation. As a result, the DOD released an Energy Strategy which outlines ways to reduce energy requirements in order to meet both Presidential and Congressional mandates for energy security. With this research, we provide a historical review (1973–2014) of energy policy, legislation, and research. Additionally we identify gaps between strategy and research. The results show that DOD energy research lacks a unifying structure and guiding framework. We propose a knowledge management framework to unify and guide research efforts in direct support of the DOD Energy Strategy. - Highlights: •Unification of effort is needed to support strategic goals. •Provides the current state of DOD energy research. •Proposes a framework to guide DOD energy research. •Frames the DOD energy research context and landscape. •Promotes a unifying structure for DOD energy research.

WRAP Module 1 sampling strategy and waste characterization alternatives study

Energy Technology Data Exchange (ETDEWEB)

Bergeson, C.L.

1994-09-30

The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner.

WRAP Module 1 sampling strategy and waste characterization alternatives study

International Nuclear Information System (INIS)

Bergeson, C.L.

1994-01-01

The Waste Receiving and Processing Module 1 Facility is designed to examine, process, certify, and ship drums and boxes of solid wastes that have a surface dose equivalent of less than 200 mrem/h. These wastes will include low-level and transuranic wastes that are retrievably stored in the 200 Area burial grounds and facilities in addition to newly generated wastes. Certification of retrievably stored wastes processing in WRAP 1 is required to meet the waste acceptance criteria for onsite treatment and disposal of low-level waste and mixed low-level waste and the Waste Isolation Pilot Plant Waste Acceptance Criteria for the disposal of TRU waste. In addition, these wastes will need to be certified for packaging in TRUPACT-II shipping containers. Characterization of the retrievably stored waste is needed to support the certification process. Characterization data will be obtained from historical records, process knowledge, nondestructive examination nondestructive assay, visual inspection of the waste, head-gas sampling, and analysis of samples taken from the waste containers. Sample characterization refers to the method or methods that are used to test waste samples for specific analytes. The focus of this study is the sample characterization needed to accurately identify the hazardous and radioactive constituents present in the retrieved wastes that will be processed in WRAP 1. In addition, some sampling and characterization will be required to support NDA calculations and to provide an over-check for the characterization of newly generated wastes. This study results in the baseline definition of WRAP 1 sampling and analysis requirements and identifies alternative methods to meet these requirements in an efficient and economical manner

Well-being improvement in a midsize employer: changes in well-being, productivity, health risk, and perceived employer support after implementation of a well-being improvement strategy.

Science.gov (United States)

Hamar, Brent; Coberley, Carter; Pope, James E; Rula, Elizabeth Y

2015-04-01

To evaluate employee well-being change and associated change in productivity, health risk including biometrics, and workplace support over 2 years after implementation of a well-being improvement strategy. This was an employer case study evaluation of well-being, productivity (presenteeism, absenteeism, and job performance), health risk, and employer support across three employee assessment spanning 2 years. Employee well-being was compared with an independent sample of workers in the community. Well-being and job performance increased and presenteeism and health risk decreased significantly over the 2 years. Employee well-being started lower and increased to exceed community worker averages, approaching significance. Well-being improvement was associated with higher productivity across all measures. Increases in employer support for well-being were associated with improved well-being and productivity. This employer's well-being strategy, including a culture supporting well-being, was associated with improved health and productivity.

Preliminary analysis of an integrated logistics system for OSSA payloads. Volume 2: OSSA integrated logistics support strategy

Science.gov (United States)

Palguta, T.; Bradley, W.; Stockton, T.

1988-01-01

The purpose is to outline an Office of Space Science and Applications (OSSA) integrated logistics support strategy that will ensure effective logistics support of OSSA payloads at an affordable life-cycle cost. Program objectives, organizational relationships, and implementation of the logistics strategy are discussed.

Life stressors, coping strategies, and social supports in patients with irritable bowel syndrome.

Science.gov (United States)

Roohafza, Hamidreza; Keshteli, Ammar Hassanzadeh; Daghaghzadeh, Hamed; Afshar, Hamid; Erfani, Zahra; Adibi, Peyman

2016-01-01

The frequency and the perceived intensity of life stressors, coping strategies, and social supports are very important in everybody's well-being. This study intended to estimate the relation of irritable bowel syndrome (IBS) and these factors. This was a cross-sectional study carried out in Isfahan on 2013. Data were extracted from the framework of the study on the epidemiology of psychological, alimentary health, and nutrition. Symptoms of IBS were evaluated by Talley bowel disease questionnaire. Stressful life event, modified COPE scale, and Multidimensional Scale of Perceived Social Support were also used. About 4763 subjects were completed questionnaires. Analyzing data were done by t -test and multivariate logistic regression. Of all returned questionnaire, 1024 (21.5%) were diagnosed with IBS. IBS and clinically-significant IBS (IBS-S) groups have significantly experienced a higher level of perceived intensity of stressors and had a higher frequency of stressors. The mean score of social supports and the mean scores of three coping strategies (problem engagement, support seeking, and positive reinterpretation and growth) were significantly lower in subjects with either IBS-S or IBS than in those with no IBS. Multivariate logistic regression revealed a significant association between frequency of stressors and perceived intensity of stressors with IBS (odds ratio [OR] =1.09 and OR = 1.02, respectively) or IBS-S (OR = 1.09 and OR = 1.03, respectively). People with IBS had higher numbers of stressors, higher perception of the intensity of stressors, less adaptive coping strategies, and less social supports which should be focused in psychosocial interventions.

Job strain and psychological distress among employed pregnant Thai women: role of social support and coping strategies.

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Sanguanklin, Natthananporn; McFarlin, Barbara L; Finnegan, Lorna; Park, Chang Gi; Giurgescu, Carmen; White-Traut, Rosemary; Engstrom, Janet L

2014-08-01

Most Thai women continue to work throughout their pregnancy; however, little is known about job strain and its relation to psychological distress. This study aimed to examine: (1) the direct effects of job strain, perceived workplace support, perceived family support, and coping strategies on psychological distress and (2) the moderating effect of perceived workplace support, perceived family support, and coping strategies on the relationship between job strain and psychological distress. Lazarus and Folkman's transactional model of stress and coping guided this cross-sectional study. Full-time employed pregnant women (N = 300) were recruited from three antenatal clinics in Thailand. Thai versions of the following instruments were used: the State-Anxiety Inventory and Center for Epidemiological Studies-Depression Scale (psychological distress), the Job Content Questionnaire (job strain and perceived workplace support), the Medical Outcome Study Social Support Survey (perceived family support), and the Ways of Coping Checklist-Revised (coping strategies). Job strain with other predictors explained 54% of the variance in psychological distress. In the separate hierarchical multiple linear regression models, two types of coping strategies, seeking social support and wishful thinking, moderated the effects of job strain on psychological distress. Perceived family support had a direct effect in reducing psychological distress. Job strain is a significant contributor to psychological distress. The average levels of seeking social support and wishful thinking were most beneficial in moderating the negative impact of job strain on psychological distress. Since perceived workplace and family support did not have moderating effects, stress management programs for decreasing the levels of job strain should be developed.

Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples

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Stéphanie Simon

2015-11-01

Full Text Available Botulinum neurotoxins (BoNTs cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A–G, of which serotypes A, B, E, and F cause the disease in humans. BoNTs are classified as “category A” bioterrorism threat agents and are relevant in the context of the Biological Weapons Convention. An international proficiency test (PT was conducted to evaluate detection, quantification and discrimination capabilities of 23 expert laboratories from the health, food and security areas. Here we describe three immunological strategies that proved to be successful for the detection and quantification of BoNT/A, B, and E considering the restricted sample volume (1 mL distributed. To analyze the samples qualitatively and quantitatively, the first strategy was based on sensitive immunoenzymatic and immunochromatographic assays for fast qualitative and quantitative analyses. In the second approach, a bead-based suspension array was used for screening followed by conventional ELISA for quantification. In the third approach, an ELISA plate format assay was used for serotype specific immunodetection of BoNT-cleaved substrates, detecting the activity of the light chain, rather than the toxin protein. The results provide guidance for further steps in quality assurance and highlight problems to address in the future.

Recommended Immunological Strategies to Screen for Botulinum Neurotoxin-Containing Samples.

Science.gov (United States)

Simon, Stéphanie; Fiebig, Uwe; Liu, Yvonne; Tierney, Rob; Dano, Julie; Worbs, Sylvia; Endermann, Tanja; Nevers, Marie-Claire; Volland, Hervé; Sesardic, Dorothea; Dorner, Martin B

2015-11-26

Botulinum neurotoxins (BoNTs) cause the life-threatening neurological illness botulism in humans and animals and are divided into seven serotypes (BoNT/A-G), of which serotypes A, B, E, and F cause the disease in humans. BoNTs are classified as "category A" bioterrorism threat agents and are relevant in the context of the Biological Weapons Convention. An international proficiency test (PT) was conducted to evaluate detection, quantification and discrimination capabilities of 23 expert laboratories from the health, food and security areas. Here we describe three immunological strategies that proved to be successful for the detection and quantification of BoNT/A, B, and E considering the restricted sample volume (1 mL) distributed. To analyze the samples qualitatively and quantitatively, the first strategy was based on sensitive immunoenzymatic and immunochromatographic assays for fast qualitative and quantitative analyses. In the second approach, a bead-based suspension array was used for screening followed by conventional ELISA for quantification. In the third approach, an ELISA plate format assay was used for serotype specific immunodetection of BoNT-cleaved substrates, detecting the activity of the light chain, rather than the toxin protein. The results provide guidance for further steps in quality assurance and highlight problems to address in the future.

Designing efficient nitrous oxide sampling strategies in agroecosystems using simulation models

Science.gov (United States)

Debasish Saha; Armen R. Kemanian; Benjamin M. Rau; Paul R. Adler; Felipe Montes

2017-01-01

Annual cumulative soil nitrous oxide (N2O) emissions calculated from discrete chamber-based flux measurements have unknown uncertainty. We used outputs from simulations obtained with an agroecosystem model to design sampling strategies that yield accurate cumulative N2O flux estimates with a known uncertainty level. Daily soil N2O fluxes were simulated for Ames, IA (...

Is Support of Censoring Controversial Media Content for the Good of Others? Sexual Strategies and Support of Censoring Pro-Alcohol Advertising.

Science.gov (United States)

Zhang, Jinguang

2017-01-01

At least in the United States, there are widespread concerns with advertising that encourages alcohol consumption, and previous research explains those concerns as aiming to protect others from the harm of excessive alcohol use. 1 Drawing on sexual strategies theory, we hypothesized that support of censoring pro-alcohol advertising is ultimately self-benefiting regardless of its altruistic effect at a proximate level. Excessive drinking positively correlates with having casual sex, and casual sex threatens monogamy, one of the major means with which people adopting a long-term sexual strategy increase their inclusive fitness. Then, one way for long-term strategists to protect monogamy, and thus their reproductive interest is to support censoring pro-alcohol advertising, thereby preventing others from becoming excessive drinkers (and consequently having casual sex) under media influence. Supporting this hypothesis, three studies consistently showed that restricted sociosexuality positively correlated with support of censoring pro-alcohol advertising before and after various value-, ideological-, and moral-foundation variables were controlled for. Also as predicted, Study 3 revealed a significant indirect effect of sociosexuality on censorship support through perceived media influence on others but not through perceived media influence on self. These findings further supported a self-interest analysis of issue opinions, extended third-person-effect research on support of censoring pro-alcohol advertising, and suggested a novel approach to analyzing media censorship support.

Evaluating sampling strategies for larval cisco (Coregonus artedi)

Science.gov (United States)

Myers, J.T.; Stockwell, J.D.; Yule, D.L.; Black, J.A.

2008-01-01

To improve our ability to assess larval cisco (Coregonus artedi) populations in Lake Superior, we conducted a study to compare several sampling strategies. First, we compared density estimates of larval cisco concurrently captured in surface waters with a 2 x 1-m paired neuston net and a 0.5-m (diameter) conical net. Density estimates obtained from the two gear types were not significantly different, suggesting that the conical net is a reasonable alternative to the more cumbersome and costly neuston net. Next, we assessed the effect of tow pattern (sinusoidal versus straight tows) to examine if propeller wash affected larval density. We found no effect of propeller wash on the catchability of larval cisco. Given the availability of global positioning systems, we recommend sampling larval cisco using straight tows to simplify protocols and facilitate straightforward measurements of volume filtered. Finally, we investigated potential trends in larval cisco density estimates by sampling four time periods during the light period of a day at individual sites. Our results indicate no significant trends in larval density estimates during the day. We conclude estimates of larval cisco density across space are not confounded by time at a daily timescale. Well-designed, cost effective surveys of larval cisco abundance will help to further our understanding of this important Great Lakes forage species.

STRATEGIES SUPPORTING THE HEALTH PROCESS AS EXPERIENCED BY WOMEN WITH A LIFE THREATENING DISEASE AND EXCELLENT NURSES

DEFF Research Database (Denmark)

Jensen, Kirsten Pryds

1999-01-01

were used, a descriptive phenomenological method, and a descriptive exploratory method. Ten Danish women, suffering from breast cancer, and sixteen Swedish excellent nurses were interviewed. The patients' health strategies appeared to be dependent on their determination to go on living. In the health...... process, it was found imperative that the patient worked actively, created something to live for, and achieved a harmonious relationship with supportive significant others and nature. In the process the patient experienced awareness and avoidance and gained insights about life itself (paper I......). The patients perceived the supportive health strategies performed by the excellent nurse as, being able to "catch their wavelength” and in a positive, genuine, supportive connectedness, transfer knowledge and courage to them (paper II). The nurses perceived the supportive health strategies performed...

Paediatric death and dying: exploring coping strategies of health professionals and perceptions of support provision.

Science.gov (United States)

Forster, Elizabeth; Hafiz, Alaa

2015-06-01

Without question a child's death is a devastating event for parents and families. Health professionals working with the dying child and family draw upon their expertise and experience to engage with children, parents and families on this painful journey. This is a delicate and sensitive area of practice and has strong and penetrating effects on health professionals. They employ physical, emotional, spiritual and problem solving strategies to continue to perform this role effectively and to protect their continued sense of wellbeing. To explore health professionals' perceptions of bereavement support surrounding the loss of a child. The research was underpinned by social constructionism. Semi-structured interviews were held with 10 health professionals including doctors, nurses and social workers who were directly involved in the care of the dying child and family in 7 cases of paediatric death. Health professional narratives were analysed consistent with Charmarz's (2006) approach. For health professionals, constructions around coping emerged as peer support, personal coping strategies, family support, physical impact of support and spiritual beliefs. Analysis of the narratives also revealed health professionals' perceptions of their support provision. Health professionals involved in caring for dying children and their families use a variety of strategies to cope with the emotional and physical toll of providing support. They also engage in self-assessment to evaluate their support provision and this highlights the need for self-evaluation tools in paediatric palliative care.

Population Pharmacokinetics and Optimal Sampling Strategy for Model-Based Precision Dosing of Melphalan in Patients Undergoing Hematopoietic Stem Cell Transplantation.

Science.gov (United States)

Mizuno, Kana; Dong, Min; Fukuda, Tsuyoshi; Chandra, Sharat; Mehta, Parinda A; McConnell, Scott; Anaissie, Elias J; Vinks, Alexander A

2018-05-01

High-dose melphalan is an important component of conditioning regimens for patients undergoing hematopoietic stem cell transplantation. The current dosing strategy based on body surface area results in a high incidence of oral mucositis and gastrointestinal and liver toxicity. Pharmacokinetically guided dosing will individualize exposure and help minimize overexposure-related toxicity. The purpose of this study was to develop a population pharmacokinetic model and optimal sampling strategy. A population pharmacokinetic model was developed with NONMEM using 98 observations collected from 15 adult patients given the standard dose of 140 or 200 mg/m 2 by intravenous infusion. The determinant-optimal sampling strategy was explored with PopED software. Individual area under the curve estimates were generated by Bayesian estimation using full and the proposed sparse sampling data. The predictive performance of the optimal sampling strategy was evaluated based on bias and precision estimates. The feasibility of the optimal sampling strategy was tested using pharmacokinetic data from five pediatric patients. A two-compartment model best described the data. The final model included body weight and creatinine clearance as predictors of clearance. The determinant-optimal sampling strategies (and windows) were identified at 0.08 (0.08-0.19), 0.61 (0.33-0.90), 2.0 (1.3-2.7), and 4.0 (3.6-4.0) h post-infusion. An excellent correlation was observed between area under the curve estimates obtained with the full and the proposed four-sample strategy (R 2  = 0.98; p strategy promises to achieve the target area under the curve as part of precision dosing.

Comparison of active and passive sampling strategies for the monitoring of pesticide contamination in streams

Science.gov (United States)

Assoumani, Azziz; Margoum, Christelle; Guillemain, Céline; Coquery, Marina

2014-05-01

The monitoring of water bodies regarding organic contaminants, and the determination of reliable estimates of concentrations are challenging issues, in particular for the implementation of the Water Framework Directive. Several strategies can be applied to collect water samples for the determination of their contamination level. Grab sampling is fast, easy, and requires little logistical and analytical needs in case of low frequency sampling campaigns. However, this technique lacks of representativeness for streams with high variations of contaminant concentrations, such as pesticides in rivers located in small agricultural watersheds. Increasing the representativeness of this sampling strategy implies greater logistical needs and higher analytical costs. Average automated sampling is therefore a solution as it allows, in a single analysis, the determination of more accurate and more relevant estimates of concentrations. Two types of automatic samplings can be performed: time-related sampling allows the assessment of average concentrations, whereas flow-dependent sampling leads to average flux concentrations. However, the purchase and the maintenance of automatic samplers are quite expensive. Passive sampling has recently been developed as an alternative to grab or average automated sampling, to obtain at lower cost, more realistic estimates of the average concentrations of contaminants in streams. These devices allow the passive accumulation of contaminants from large volumes of water, resulting in ultratrace level detection and smoothed integrative sampling over periods ranging from days to weeks. They allow the determination of time-weighted average (TWA) concentrations of the dissolved fraction of target contaminants, but they need to be calibrated in controlled conditions prior to field applications. In other words, the kinetics of the uptake of the target contaminants into the sampler must be studied in order to determine the corresponding sampling rate

Tools to support maintenance strategies under soft soil conditions

Directory of Open Access Journals (Sweden)

J. W. M. Lambert

2015-11-01

Full Text Available Costs for maintenance of infrastructure in municipalities with soft soil underground conditions, are estimated to be almost 40 % higher than in others. As a result, these municipalities meet financial problems that cause overdue maintenance. In some cases municipalities are even afraid to be unable to offer a minimum service level in future. In common, traditional practice, roads and sewerage systems have been constructed in trenches that consist of sandy material that replaces the upper meters of the soft soil. Under influence of its weight, this causes accelerated settlements of the construction. A number of alternative constructions have been developed, e.g. using light-weight materials to limit settlement velocity. In order to limit future maintenance costs, improvement of maintenance strategies is desired. Tools have been and will be developed to support municipalities in improving their maintenance strategies and save money by doing that. A model (BALANS that weighs the attractiveness of alternative solutions under different soil, environmental and economic circumstances, will be presented.

Tools and strategies for engaging the supervisor in technology-supported work-based learning : evaluation research

NARCIS (Netherlands)

Bianco, M.; Collis, Betty; Egan, Toby Marshall; Morris, Michael Lane; Inbakumar, Vinod

2004-01-01

This study reports the results of the formative evaluations of two computer-supported tools and the associated strategies for their use. Tools and strategies embedded in web-based courses can increase a supervisor’s involvement in helping employees transfer learning onto the workplace. Issues

Strategies for Supporting Physician-Scientists in Faculty Roles: A Narrative Review With Key Informant Consultations.

Science.gov (United States)

Lingard, Lorelei; Zhang, Peter; Strong, Michael; Steele, Margaret; Yoo, John; Lewis, James

2017-10-01

Physician-scientists are a population in decline globally. Solutions to reverse this decline often have focused on the training pipeline. Less attention has been paid to reducing attrition post training, when physician-scientists take up faculty roles. However, this period is a known time of vulnerability because of the pressures of clinical duties and the long timeline to securing independent research funding. This narrative review explored existing knowledge regarding how best to support physician-scientists for success in their faculty roles. The authors searched the Medline, Embase, ERIC, and Cochrane Library databases for articles published from 2000 to 2016 on this topic and interviewed key informants in 2015 to solicit their input on the review results. The authors reviewed 78 articles and interviewed 16 key informants. From the literature, they developed a framework of organizational (facilitate mentorship, foster community, value the physician-scientist role, minimize financial barriers) and individual (develop professional and research skills) strategies for supporting physician-scientists. They also outlined key knowledge gaps representing topics either rarely or never addressed in the reviewed articles (percent research time, structural hypocrisy, objective assessment, group metrics, professional identity). The key informants confirmed the identified strategies and discussed how the gaps were particularly important and impactful. This framework offers a basis for assessing an organization's existing support strategies, identifying outstanding needs, and developing targeted programming. The identified gaps require attention, as they threaten to undermine the benefits of existing support strategies.

Infertility Stress: The Role of Coping Strategies, Personality Trait, and Social Support

Directory of Open Access Journals (Sweden)

Batool Rashidi

2011-12-01

Full Text Available Objective: The aim of our study was to investigate the effect of coping strategies, personality trait and social support as the main social and psychological factors on infertility stress.Materials and methods: This study was conducted on 201 infertile Iranian women referred to the Vali-e-Asr Reproductive health Research Center, and completed the following questionnaires: The fertility problem inventory, measuring perceived infertility related stress (Newton CR, 1999, big five factor personality questionnaire (Farahani, 2009, multidimensional scale of perceived social support MSPS (Zimmet 1988, and multidimensional assessment of coping (Endler, 1990.The results were then analyzed using the Pearson Correlation and stepwise regression.Results: Infertility stress has negative and significant relation with emotion-oriented coping method, perceived social support and bring extrovert. It has a positive, significant relation with emotion-oriented coping method, obsessive compulsive disorder (OCD. The results of the stepwise regression showed that emotion-oriented coping method, OCD and being extrovert are suitable predictors of infertility stress.Conclusion: About 22% of the infertility stress variance was explained by coping strategies and personality trait. Therefore our result demonstrates the importance of social and psychological factors on experiencing the infertility stress.

Sampling strategies to measure the prevalence of common recurrent infections in longitudinal studies

Directory of Open Access Journals (Sweden)

Luby Stephen P

2010-08-01

Full Text Available Abstract Background Measuring recurrent infections such as diarrhoea or respiratory infections in epidemiological studies is a methodological challenge. Problems in measuring the incidence of recurrent infections include the episode definition, recall error, and the logistics of close follow up. Longitudinal prevalence (LP, the proportion-of-time-ill estimated by repeated prevalence measurements, is an alternative measure to incidence of recurrent infections. In contrast to incidence which usually requires continuous sampling, LP can be measured at intervals. This study explored how many more participants are needed for infrequent sampling to achieve the same study power as frequent sampling. Methods We developed a set of four empirical simulation models representing low and high risk settings with short or long episode durations. The model was used to evaluate different sampling strategies with different assumptions on recall period and recall error. Results The model identified three major factors that influence sampling strategies: (1 the clustering of episodes in individuals; (2 the duration of episodes; (3 the positive correlation between an individual's disease incidence and episode duration. Intermittent sampling (e.g. 12 times per year often requires only a slightly larger sample size compared to continuous sampling, especially in cluster-randomized trials. The collection of period prevalence data can lead to highly biased effect estimates if the exposure variable is associated with episode duration. To maximize study power, recall periods of 3 to 7 days may be preferable over shorter periods, even if this leads to inaccuracy in the prevalence estimates. Conclusion Choosing the optimal approach to measure recurrent infections in epidemiological studies depends on the setting, the study objectives, study design and budget constraints. Sampling at intervals can contribute to making epidemiological studies and trials more efficient, valid

OUTPACE long duration stations: physical variability, context of biogeochemical sampling, and evaluation of sampling strategy

Directory of Open Access Journals (Sweden)

A. de Verneil

2018-04-01

Full Text Available Research cruises to quantify biogeochemical fluxes in the ocean require taking measurements at stations lasting at least several days. A popular experimental design is the quasi-Lagrangian drifter, often mounted with in situ incubations or sediment traps that follow the flow of water over time. After initial drifter deployment, the ship tracks the drifter for continuing measurements that are supposed to represent the same water environment. An outstanding question is how to best determine whether this is true. During the Oligotrophy to UlTra-oligotrophy PACific Experiment (OUTPACE cruise, from 18 February to 3 April 2015 in the western tropical South Pacific, three separate stations of long duration (five days over the upper 500 m were conducted in this quasi-Lagrangian sampling scheme. Here we present physical data to provide context for these three stations and to assess whether the sampling strategy worked, i.e., that a single body of water was sampled. After analyzing tracer variability and local water circulation at each station, we identify water layers and times where the drifter risks encountering another body of water. While almost no realization of this sampling scheme will be truly Lagrangian, due to the presence of vertical shear, the depth-resolved observations during the three stations show most layers sampled sufficiently homogeneous physical environments during OUTPACE. By directly addressing the concerns raised by these quasi-Lagrangian sampling platforms, a protocol of best practices can begin to be formulated so that future research campaigns include the complementary datasets and analyses presented here to verify the appropriate use of the drifter platform.

Comparison of sampling strategies for tobacco retailer inspections to maximize coverage in vulnerable areas and minimize cost.

Science.gov (United States)

Lee, Joseph G L; Shook-Sa, Bonnie E; Bowling, J Michael; Ribisl, Kurt M

2017-06-23

In the United States, tens of thousands of inspections of tobacco retailers are conducted each year. Various sampling choices can reduce travel costs, emphasize enforcement in areas with greater non-compliance, and allow for comparability between states and over time. We sought to develop a model sampling strategy for state tobacco retailer inspections. Using a 2014 list of 10,161 North Carolina tobacco retailers, we compared results from simple random sampling; stratified, clustered at the ZIP code sampling; and, stratified, clustered at the census tract sampling. We conducted a simulation of repeated sampling and compared approaches for their comparative level of precision, coverage, and retailer dispersion. While maintaining an adequate design effect and statistical precision appropriate for a public health enforcement program, both stratified, clustered ZIP- and tract-based approaches were feasible. Both ZIP and tract strategies yielded improvements over simple random sampling, with relative improvements, respectively, of average distance between retailers (reduced 5.0% and 1.9%), percent Black residents in sampled neighborhoods (increased 17.2% and 32.6%), percent Hispanic residents in sampled neighborhoods (reduced 2.2% and increased 18.3%), percentage of sampled retailers located near schools (increased 61.3% and 37.5%), and poverty rate in sampled neighborhoods (increased 14.0% and 38.2%). States can make retailer inspections more efficient and targeted with stratified, clustered sampling. Use of statistically appropriate sampling strategies like these should be considered by states, researchers, and the Food and Drug Administration to improve program impact and allow for comparisons over time and across states. The authors present a model tobacco retailer sampling strategy for promoting compliance and reducing costs that could be used by U.S. states and the Food and Drug Administration (FDA). The design is feasible to implement in North Carolina. Use of

Low-Z polymer sample supports for fixed-target serial femtosecond X-ray crystallography

Energy Technology Data Exchange (ETDEWEB)

Feld, Geoffrey K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); National Institute of Environmental Health Science, Research Triangle Park, NC (United States); Heymann, Michael [Brandeis Univ., Waltham, MA (United States); Univ. of Hamburg and DESY, Hamburg (Germany); Benner, W. Henry [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Pardini, Tommaso [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Tsai, Ching -Ju [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Boutet, Sebastien [SLAC National Accelerator Lab., Menlo Park, CA (United States); Coleman, Matthew A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Hunter, Mark S. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); SLAC National Accelerator Lab., Menlo Park, CA (United States); Li, Xiaodan [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Messerschmidt, Marc [SLAC National Accelerator Lab., Menlo Park, CA (United States); BioXFEL Science and Technology Center, Buffalo, NY (United States); Opathalage, Achini [Brandeis Univ., Waltham, MA (United States); Pedrini, Bill [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Williams, Garth J. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Krantz, Bryan A. [Univ. of California, Berkeley, CA (United States); Fraden, Seth [Brandeis Univ., Waltham, MA (United States); Hau-Riege, Stefan [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Evans, James E. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Segelke, Brent W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Frank, Matthias [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2015-06-27

X-ray free-electron lasers (XFELs) offer a new avenue to the structural probing of complex materials, including biomolecules. Delivery of precious sample to the XFEL beam is a key consideration, as the sample of interest must be serially replaced after each destructive pulse. The fixed-target approach to sample delivery involves depositing samples on a thin-film support and subsequent serial introduction via a translating stage. Some classes of biological materials, including two-dimensional protein crystals, must be introduced on fixed-target supports, as they require a flat surface to prevent sample wrinkling. A series of wafer and transmission electron microscopy (TEM)-style grid supports constructed of low-Z plastic have been custom-designed and produced. Aluminium TEM grid holders were engineered, capable of delivering up to 20 different conventional or plastic TEM grids using fixed-target stages available at the Linac Coherent Light Source (LCLS). As proof-of-principle, X-ray diffraction has been demonstrated from two-dimensional crystals of bacteriorhodopsin and three-dimensional crystals of anthrax toxin protective antigen mounted on these supports at the LCLS. In conclusion, the benefits and limitations of these low-Z fixed-target supports are discussed; it is the authors' belief that they represent a viable and efficient alternative to previously reported fixed-target supports for conducting diffraction studies with XFELs.

Building Employer Capacity to Support Meaningful Employment for Persons with Developmental Disabilities: A Grounded Theory Study of Employment Support Perspectives.

Science.gov (United States)

Rashid, Marghalara; Hodgetts, Sandra; Nicholas, David

2017-11-01

To explore strategies to build employer capacity to support people with DD in meaningful employment from perspective of employment support workers. A grounded theory study was conducted with 34 employment support individuals. A theoretical sampling approach was used to identify and recruit participants from multiple sites in Ontario and Alberta. Three main themes, with seven sub-themes, emerged: (1) experiences of supporting employment finding for people with DD, (2) institutional influences on employee experiences, and (3) attitudes, assumptions and stigma. Several recommendations related to building employer capacity were offered. Our findings provide insight on specific elements and strategies that can support building employer capacity for persons with DD.

Language-based communication strategies that support person-centered communication with persons with dementia.

Science.gov (United States)

Savundranayagam, Marie Y; Moore-Nielsen, Kelsey

2015-10-01

There are many recommended language-based strategies for effective communication with persons with dementia. What is unknown is whether effective language-based strategies are also person centered. Accordingly, the objective of this study was to examine whether language-based strategies for effective communication with persons with dementia overlapped with the following indicators of person-centered communication: recognition, negotiation, facilitation, and validation. Conversations (N = 46) between staff-resident dyads were audio-recorded during routine care tasks over 12 weeks. Staff utterances were coded twice, using language-based and person-centered categories. There were 21 language-based categories and 4 person-centered categories. There were 5,800 utterances transcribed: 2,409 without indicators, 1,699 coded as language or person centered, and 1,692 overlapping utterances. For recognition, 26% of utterances were greetings, 21% were affirmations, 13% were questions (yes/no and open-ended), and 15% involved rephrasing. Questions (yes/no, choice, and open-ended) comprised 74% of utterances that were coded as negotiation. A similar pattern was observed for utterances coded as facilitation where 51% of utterances coded as facilitation were yes/no questions, open-ended questions, and choice questions. However, 21% of facilitative utterances were affirmations and 13% involved rephrasing. Finally, 89% of utterances coded as validation were affirmations. The findings identify specific language-based strategies that support person-centered communication. However, between 1 and 4, out of a possible 21 language-based strategies, overlapped with at least 10% of utterances coded as each person-centered indicator. This finding suggests that staff need training to use more diverse language strategies that support personhood of residents with dementia.

Sampling strategies for tropical forest nutrient cycling studies: a case study in São Paulo, Brazil

Directory of Open Access Journals (Sweden)

G. Sparovek

1997-12-01

Full Text Available The precise sampling of soil, biological or micro climatic attributes in tropical forests, which are characterized by a high diversity of species and complex spatial variability, is a difficult task. We found few basic studies to guide sampling procedures. The objective of this study was to define a sampling strategy and data analysis for some parameters frequently used in nutrient cycling studies, i. e., litter amount, total nutrient amounts in litter and its composition (Ca, Mg, Κ, Ν and P, and soil attributes at three depths (organic matter, Ρ content, cation exchange capacity and base saturation. A natural remnant forest in the West of São Paulo State (Brazil was selected as study area and samples were collected in July, 1989. The total amount of litter and its total nutrient amounts had a high spatial independent variance. Conversely, the variance of litter composition was lower and the spatial dependency was peculiar to each nutrient. The sampling strategy for the estimation of litter amounts and the amount of nutrient in litter should be different than the sampling strategy for nutrient composition. For the estimation of litter amounts and the amount of nutrients in litter (related to quantity a large number of randomly distributed determinations are needed. Otherwise, for the estimation of litter nutrient composition (related to quality a smaller amount of spatially located samples should be analyzed. The determination of sampling for soil attributes differed according to the depth. Overall, surface samples (0-5 cm showed high short distance spatial dependent variance, whereas, subsurface samples exhibited spatial dependency in longer distances. Short transects with sampling interval of 5-10 m are recommended for surface sampling. Subsurface samples must also be spatially located, but with transects or grids with longer distances between sampling points over the entire area. Composite soil samples would not provide a complete

Clinical usefulness of limited sampling strategies for estimating AUC of proton pump inhibitors.

Science.gov (United States)

Niioka, Takenori

2011-03-01

Cytochrome P450 (CYP) 2C19 (CYP2C19) genotype is regarded as a useful tool to predict area under the blood concentration-time curve (AUC) of proton pump inhibitors (PPIs). In our results, however, CYP2C19 genotypes had no influence on AUC of all PPIs during fluvoxamine treatment. These findings suggest that CYP2C19 genotyping is not always a good indicator for estimating AUC of PPIs. Limited sampling strategies (LSS) were developed to estimate AUC simply and accurately. It is important to minimize the number of blood samples because of patient's acceptance. This article reviewed the usefulness of LSS for estimating AUC of three PPIs (omeprazole: OPZ, lansoprazole: LPZ and rabeprazole: RPZ). The best prediction formulas in each PPI were AUC(OPZ)=9.24 x C(6h)+2638.03, AUC(LPZ)=12.32 x C(6h)+3276.09 and AUC(RPZ)=1.39 x C(3h)+7.17 x C(6h)+344.14, respectively. In order to optimize the sampling strategy of LPZ, we tried to establish LSS for LPZ using a time point within 3 hours through the property of pharmacokinetics of its enantiomers. The best prediction formula using the fewest sampling points (one point) was AUC(racemic LPZ)=6.5 x C(3h) of (R)-LPZ+13.7 x C(3h) of (S)-LPZ-9917.3 x G1-14387.2×G2+7103.6 (G1: homozygous extensive metabolizer is 1 and the other genotypes are 0; G2: heterozygous extensive metabolizer is 1 and the other genotypes are 0). Those strategies, plasma concentration monitoring at one or two time-points, might be more suitable for AUC estimation than reference to CYP2C19 genotypes, particularly in the case of coadministration of CYP mediators.

Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform.

Science.gov (United States)

Mitra, Abhishek; Skrzypczak, Magdalena; Ginalski, Krzysztof; Rowicka, Maga

2015-01-01

Sequencing microRNA, reduced representation sequencing, Hi-C technology and any method requiring the use of in-house barcodes result in sequencing libraries with low initial sequence diversity. Sequencing such data on the Illumina platform typically produces low quality data due to the limitations of the Illumina cluster calling algorithm. Moreover, even in the case of diverse samples, these limitations are causing substantial inaccuracies in multiplexed sample assignment (sample bleeding). Such inaccuracies are unacceptable in clinical applications, and in some other fields (e.g. detection of rare variants). Here, we discuss how both problems with quality of low-diversity samples and sample bleeding are caused by incorrect detection of clusters on the flowcell during initial sequencing cycles. We propose simple software modifications (Long Template Protocol) that overcome this problem. We present experimental results showing that our Long Template Protocol remarkably increases data quality for low diversity samples, as compared with the standard analysis protocol; it also substantially reduces sample bleeding for all samples. For comprehensiveness, we also discuss and compare experimental results from alternative approaches to sequencing low diversity samples. First, we discuss how the low diversity problem, if caused by barcodes, can be avoided altogether at the barcode design stage. Second and third, we present modified guidelines, which are more stringent than the manufacturer's, for mixing low diversity samples with diverse samples and lowering cluster density, which in our experience consistently produces high quality data from low diversity samples. Fourth and fifth, we present rescue strategies that can be applied when sequencing results in low quality data and when there is no more biological material available. In such cases, we propose that the flowcell be re-hybridized and sequenced again using our Long Template Protocol. Alternatively, we discuss how

Strategies for achieving high sequencing accuracy for low diversity samples and avoiding sample bleeding using illumina platform.

Directory of Open Access Journals (Sweden)

Abhishek Mitra

Full Text Available Sequencing microRNA, reduced representation sequencing, Hi-C technology and any method requiring the use of in-house barcodes result in sequencing libraries with low initial sequence diversity. Sequencing such data on the Illumina platform typically produces low quality data due to the limitations of the Illumina cluster calling algorithm. Moreover, even in the case of diverse samples, these limitations are causing substantial inaccuracies in multiplexed sample assignment (sample bleeding. Such inaccuracies are unacceptable in clinical applications, and in some other fields (e.g. detection of rare variants. Here, we discuss how both problems with quality of low-diversity samples and sample bleeding are caused by incorrect detection of clusters on the flowcell during initial sequencing cycles. We propose simple software modifications (Long Template Protocol that overcome this problem. We present experimental results showing that our Long Template Protocol remarkably increases data quality for low diversity samples, as compared with the standard analysis protocol; it also substantially reduces sample bleeding for all samples. For comprehensiveness, we also discuss and compare experimental results from alternative approaches to sequencing low diversity samples. First, we discuss how the low diversity problem, if caused by barcodes, can be avoided altogether at the barcode design stage. Second and third, we present modified guidelines, which are more stringent than the manufacturer's, for mixing low diversity samples with diverse samples and lowering cluster density, which in our experience consistently produces high quality data from low diversity samples. Fourth and fifth, we present rescue strategies that can be applied when sequencing results in low quality data and when there is no more biological material available. In such cases, we propose that the flowcell be re-hybridized and sequenced again using our Long Template Protocol. Alternatively

Sample design and gamma-ray counting strategy of neutron activation system for triton burnup measurements in KSTAR

Energy Technology Data Exchange (ETDEWEB)

Jo, Jungmin [Department of Energy System Engineering, Seoul National University, Seoul (Korea, Republic of); Cheon, Mun Seong [ITER Korea, National Fusion Research Institute, Daejeon (Korea, Republic of); Chung, Kyoung-Jae, E-mail: jkjlsh1@snu.ac.kr [Department of Energy System Engineering, Seoul National University, Seoul (Korea, Republic of); Hwang, Y.S. [Department of Energy System Engineering, Seoul National University, Seoul (Korea, Republic of)

2016-11-01

Highlights: • Sample design for triton burnup ratio measurement is carried out. • Samples for 14.1 MeV neutron measurements are selected for KSTAR. • Si and Cu are the most suitable materials for d-t neutron measurements. • Appropriate γ-ray counting strategies for each selected sample are established. - Abstract: On the purpose of triton burnup measurements in Korea Superconducting Tokamak Advanced Research (KSTAR) deuterium plasmas, appropriate neutron activation system (NAS) samples for 14.1 MeV d-t neutron measurements have been designed and gamma-ray counting strategy is established. Neutronics calculations are performed with the MCNP5 neutron transport code for the KSTAR neutral beam heated deuterium plasma discharges. Based on those calculations and the assumed d-t neutron yield, the activities induced by d-t neutrons are estimated with the inventory code FISPACT-2007 for candidate sample materials: Si, Cu, Al, Fe, Nb, Co, Ti, and Ni. It is found that Si, Cu, Al, and Fe are suitable for the KSATR NAS in terms of the minimum detectable activity (MDA) calculated based on the standard deviation of blank measurements. Considering background gamma-rays radiated from surrounding structures activated by thermalized fusion neutrons, appropriate gamma-ray counting strategy for each selected sample is established.

Perceived Parental Barriers to and Strategies for Supporting Physical Activity and Healthy Eating among Head Start Children.

Science.gov (United States)

Ling, Jiying; B Robbins, Lorraine; Hines-Martin, Vicki

2016-06-01

Despite the need for parents to support their children's healthy behaviors, knowledge of factors preventing parents from doing so is still rudimentary. This study primarily aimed to explore perceived parental barriers to and strategies for supporting physical activity and healthy eating among Head Start children. A semi-structured interview format was used with four focus groups conducted at two urban Head Start centers in the Midwestern U.S. A qualitative content analysis of audio-recorded sessions was facilitated using ATLAS.ti7. A convenience sample of 32 parents (Mage = 34.97 years) participated. Over half were female (78.1 %), African Americans (65.6 %), and single (65.6 %). About 61.3 % reported an annual family income parent): lack of time and cooking skills and a tight family budget; and (3) environmental: inaccessible programs, lack of age-appropriate education, electronic media use, and unsafe environment. Parents across all groups expressed high interest in enrolling in a program with their children. Recommendations included: parents' support team; family outings at parks; taking a walk or enrolling in a class with children; and planting a garden. Many parents showed their preference for face-to-face meetings and a support group, but repulsion of counseling. To promote parental support in future interventions with Head Start children, their perceived intrapersonal, interpersonal, and environmental barriers should be considered as intervention targets. Involving parents through a support group and face-to-face meetings is recommended.

Improving snow density estimation for mapping SWE with Lidar snow depth: assessment of uncertainty in modeled density and field sampling strategies in NASA SnowEx

Science.gov (United States)

Raleigh, M. S.; Smyth, E.; Small, E. E.

2017-12-01

The spatial distribution of snow water equivalent (SWE) is not sufficiently monitored with either remotely sensed or ground-based observations for water resources management. Recent applications of airborne Lidar have yielded basin-wide mapping of SWE when combined with a snow density model. However, in the absence of snow density observations, the uncertainty in these SWE maps is dominated by uncertainty in modeled snow density rather than in Lidar measurement of snow depth. Available observations tend to have a bias in physiographic regime (e.g., flat open areas) and are often insufficient in number to support testing of models across a range of conditions. Thus, there is a need for targeted sampling strategies and controlled model experiments to understand where and why different snow density models diverge. This will enable identification of robust model structures that represent dominant processes controlling snow densification, in support of basin-scale estimation of SWE with remotely-sensed snow depth datasets. The NASA SnowEx mission is a unique opportunity to evaluate sampling strategies of snow density and to quantify and reduce uncertainty in modeled snow density. In this presentation, we present initial field data analyses and modeling results over the Colorado SnowEx domain in the 2016-2017 winter campaign. We detail a framework for spatially mapping the uncertainty in snowpack density, as represented across multiple models. Leveraging the modular SUMMA model, we construct a series of physically-based models to assess systematically the importance of specific process representations to snow density estimates. We will show how models and snow pit observations characterize snow density variations with forest cover in the SnowEx domains. Finally, we will use the spatial maps of density uncertainty to evaluate the selected locations of snow pits, thereby assessing the adequacy of the sampling strategy for targeting uncertainty in modeled snow density.

Get a Little Closer: Further Examination of Nonverbal Comforting Strategies.

Science.gov (United States)

Bullis, Connie; Horn, Charlotte

1995-01-01

Tests whether a set of nonverbal comforting strategies and their relationships with affective orientation and gender in previous research are generalizable to a broader sample. Concludes gender differences in affective orientation, diversity and number of strategies, and use of specific strategies were supported. Finds that females were more…

Social Networking and Social Support in Tourism Experience: The Moderating Role of Online Self-Presentation Strategies

DEFF Research Database (Denmark)

Kim, Jeongmi; Tussyadiah, Iis

2013-01-01

The purpose of this study is to provide an understanding of how tourists' self-presentation is managed on social networking sites (SNS). Specifically, the study investigated the effects of SNS use on social support and tourism experience and the moderating role of the different tourists' self......-presentation strategies. The results emphasize the importance of SNS use for tourists to seek support from their social network while traveling. The study clarifies the importance of SNS use for tourism experience, in that the more tourists are engaged in social activities through SNS while traveling, the more social...... support they will get, which will contribute positively to their tourism experience. Also, it is argued that social support does not always directly result from the intense SNS use, but rather moderated by tourists' self-presentation strategies....

The role of coping strategies and self-efficacy as predictors of life satisfaction in a sample of parents of children with autism spectrum disorder.

Science.gov (United States)

Luque Salas, Bárbara; Yáñez Rodríguez, Virginia; Tabernero Urbieta, Carmen; Cuadrado, Esther

2017-02-01

This research aims to understand the role of coping strategies and self-efficacy expectations as predictors of life satisfaction in a sample of parents of boys and girls diagnosed with autistic spectrum disorder. A total of 129 parents (64 men and 65 women) answered a questionnaire on life-satisfaction, coping strategies and self-efficacy scales. Using a regression model, results show that the age of the child is associated with a lower level of satisfaction in parents. The results show that self-efficacy is the variable that best explains the level of satisfaction in mothers, while the use of problem solving explains a higher level of satisfaction in fathers. Men and women show similar levels of life satisfaction; however significant differences were found in coping strategies where women demonstrated higher expressing emotions and social support strategies than men. The development of functional coping strategies and of a high level of self-efficacy represents a key tool for adapting to caring for children with autism. Our results indicated the necessity of early intervention with parents to promote coping strategies, self-efficacy and high level of life satisfaction.

Teachers' challenges, strategies, and support needs in schools affected by community violence: a qualitative study.

Science.gov (United States)

Maring, Elisabeth F; Koblinsky, Sally A

2013-06-01

Exposure to community violence compromises teacher effectiveness, student learning, and socioemotional well-being. This study examined the challenges, strategies, and support needs of teachers in urban schools affected by high levels of community violence. Twenty teachers from 3 urban middle schools with predominantly low-income African American students completed open-ended interviews. Selected schools were in geographic areas with high violent crime levels. Consistent with an ecological risk and resilience framework, findings revealed that teachers experienced challenges and adopted coping strategies at the individual, family, school, and community levels. Teachers employed a number of strategies associated with resilience, such as prayer and seeking support from family and colleagues, but also engaged in some avoidant strategies, such as emotional withdrawal and avoiding difficult students. Findings suggest interventions to improve school safety and reduce the negative impact of violence-related stressors. Teacher training in behavior management, effective school leadership, improved school security, peer mediation, expanded mental health services, and parent involvement may promote resilience among both teachers and their students. © 2013, American School Health Association.

Decision support tool for soil sampling of heterogeneous pesticide (chlordecone) pollution.

Science.gov (United States)

Clostre, Florence; Lesueur-Jannoyer, Magalie; Achard, Raphaël; Letourmy, Philippe; Cabidoche, Yves-Marie; Cattan, Philippe

2014-02-01

When field pollution is heterogeneous due to localized pesticide application, as is the case of chlordecone (CLD), the mean level of pollution is difficult to assess. Our objective was to design a decision support tool to optimize soil sampling. We analyzed the CLD heterogeneity of soil content at 0-30- and 30-60-cm depth. This was done within and between nine plots (0.4 to 1.8 ha) on andosol and ferralsol. We determined that 20 pooled subsamples per plot were a satisfactory compromise with respect to both cost and accuracy. Globally, CLD content was greater for andosols and the upper soil horizon (0-30 cm). Soil organic carbon cannot account for CLD intra-field variability. Cropping systems and tillage practices influence the CLD content and distribution; that is CLD pollution was higher under intensive banana cropping systems and, while upper soil horizon was more polluted than the lower one with shallow tillage (pollution in the soil profile. The decision tool we proposed compiles and organizes these results to better assess CLD soil pollution in terms of sampling depth, distance, and unit at field scale. It accounts for sampling objectives, farming practices (cropping system, tillage), type of soil, and topographical characteristics (slope) to design a relevant sampling plan. This decision support tool is also adaptable to other types of heterogeneous agricultural pollution at field level.

Limited sampling strategy models for estimating the AUC of gliclazide in Chinese healthy volunteers.

Science.gov (United States)

Huang, Ji-Han; Wang, Kun; Huang, Xiao-Hui; He, Ying-Chun; Li, Lu-Jin; Sheng, Yu-Cheng; Yang, Juan; Zheng, Qing-Shan

2013-06-01

The aim of this work is to reduce the cost of required sampling for the estimation of the area under the gliclazide plasma concentration versus time curve within 60 h (AUC0-60t ). The limited sampling strategy (LSS) models were established and validated by the multiple regression model within 4 or fewer gliclazide concentration values. Absolute prediction error (APE), root of mean square error (RMSE) and visual prediction check were used as criterion. The results of Jack-Knife validation showed that 10 (25.0 %) of the 40 LSS based on the regression analysis were not within an APE of 15 % using one concentration-time point. 90.2, 91.5 and 92.4 % of the 40 LSS models were capable of prediction using 2, 3 and 4 points, respectively. Limited sampling strategies were developed and validated for estimating AUC0-60t of gliclazide. This study indicates that the implementation of an 80 mg dosage regimen enabled accurate predictions of AUC0-60t by the LSS model. This study shows that 12, 6, 4, 2 h after administration are the key sampling times. The combination of (12, 2 h), (12, 8, 2 h) or (12, 8, 4, 2 h) can be chosen as sampling hours for predicting AUC0-60t in practical application according to requirement.

Sample preparation composite and replicate strategy case studies for assay of solid oral drug products.

Science.gov (United States)

Nickerson, Beverly; Harrington, Brent; Li, Fasheng; Guo, Michele Xuemei

2017-11-30

Drug product assay is one of several tests required for new drug products to ensure the quality of the product at release and throughout the life cycle of the product. Drug product assay testing is typically performed by preparing a composite sample of multiple dosage units to obtain an assay value representative of the batch. In some cases replicate composite samples may be prepared and the reportable assay value is the average value of all the replicates. In previously published work by Harrington et al. (2014) [5], a sample preparation composite and replicate strategy for assay was developed to provide a systematic approach which accounts for variability due to the analytical method and dosage form with a standard error of the potency assay criteria based on compendia and regulatory requirements. In this work, this sample preparation composite and replicate strategy for assay is applied to several case studies to demonstrate the utility of this approach and its application at various stages of pharmaceutical drug product development. Copyright © 2017 Elsevier B.V. All rights reserved.

A preliminary evaluation of comminution and sampling strategies for radioactive cemented waste

Energy Technology Data Exchange (ETDEWEB)

Bilodeau, M.; Lastra, R.; Bouzoubaa, N. [Natural Resources Canada, Ottawa, ON (Canada); Chapman, M. [Atomic Energy of Canada Limited, Chalk River, ON (Canada)

2011-07-01

Lixiviation of Hg, U and Cs contaminants and micro-encapsulation of cemented radioactive waste (CRW) are the two main components of a CRW stabilization research project carried out at Natural Resources Canada in collaboration with Atomic Energy of Canada Limited. Unmolding CRW from the storage pail, its fragmentation into a size range suitable for both processes and the collection of a representative sample are three essential steps for providing optimal material conditions for the two studies. Separation of wires, metals and plastic incorporated into CRW samples is also required. A comminution and sampling strategy was developed to address all those needs. Dust emissions and other health and safety concerns were given full consideration. Surrogate cemented waste (SCW) was initially used for this comminution study where Cu was used as a substitute for U and Hg. SCW was characterized as a friable material through the measurement of the Bond work index of 7.7 kWh/t. A mineralogical investigation and the calibration of material heterogeneity parameters of the sampling error model showed that Cu, Hg and Cs are finely disseminated in the cement matrix. A sampling strategy was built from the model and successfully validated with radioactive waste. A larger than expected sampling error was observed with U due to the formation of large U solid phases, which were not observed with the Cu tracer. SCW samples were crushed and ground under different rock fragmentation mechanisms: compression (jaw and cone crushers, rod mill), impact (ball mill), attrition, high voltage disintegration and high pressure water (and liquid nitrogen) jetting. Cryogenic grinding was also tested with the attrition mill. Crushing and grinding technologies were assessed against criteria that were gathered from literature surveys, experiential know-how and discussion with the client and field experts. Water jetting and its liquid nitrogen variant were retained for pail cutting and waste unmolding while

A preliminary evaluation of comminution and sampling strategies for radioactive cemented waste

International Nuclear Information System (INIS)

Bilodeau, M.; Lastra, R.; Bouzoubaa, N.; Chapman, M.

2011-01-01

Lixiviation of Hg, U and Cs contaminants and micro-encapsulation of cemented radioactive waste (CRW) are the two main components of a CRW stabilization research project carried out at Natural Resources Canada in collaboration with Atomic Energy of Canada Limited. Unmolding CRW from the storage pail, its fragmentation into a size range suitable for both processes and the collection of a representative sample are three essential steps for providing optimal material conditions for the two studies. Separation of wires, metals and plastic incorporated into CRW samples is also required. A comminution and sampling strategy was developed to address all those needs. Dust emissions and other health and safety concerns were given full consideration. Surrogate cemented waste (SCW) was initially used for this comminution study where Cu was used as a substitute for U and Hg. SCW was characterized as a friable material through the measurement of the Bond work index of 7.7 kWh/t. A mineralogical investigation and the calibration of material heterogeneity parameters of the sampling error model showed that Cu, Hg and Cs are finely disseminated in the cement matrix. A sampling strategy was built from the model and successfully validated with radioactive waste. A larger than expected sampling error was observed with U due to the formation of large U solid phases, which were not observed with the Cu tracer. SCW samples were crushed and ground under different rock fragmentation mechanisms: compression (jaw and cone crushers, rod mill), impact (ball mill), attrition, high voltage disintegration and high pressure water (and liquid nitrogen) jetting. Cryogenic grinding was also tested with the attrition mill. Crushing and grinding technologies were assessed against criteria that were gathered from literature surveys, experiential know-how and discussion with the client and field experts. Water jetting and its liquid nitrogen variant were retained for pail cutting and waste unmolding while

Strategies to support engagement and continuity of activity during mealtimes for families living with dementia; a qualitative study.

Science.gov (United States)

Keller, Heather H; Martin, Lori Schindel; Dupuis, Sherry; Reimer, Holly; Genoe, Rebecca

2015-10-09

Mealtimes are an essential part of living and quality of life for everyone, including persons living with dementia. A longitudinal qualitative study provided understanding of the meaning of mealtimes for persons with dementia and their family care partners. Strategies were specifically described by families to support meaningful mealtimes. The purpose of this manuscript is to describe the strategies devised and used by these families living with dementia. A longitudinal qualitative study was undertaken to explore the meaning and experience of mealtimes for families living with dementia over a three-year period. 27 families [older person with dementia and at least one family care partner] were originally recruited from the community of South-Western Ontario. Individual and dyad interviews were conducted each year. Digitally recorded transcripts were analyzed using grounded theory methodology. Strategies were identified and categorized. Strategies to support quality mealtimes were devised by families as they adapted to their evolving lives. General strategies such as living in the moment, as well as strategies specific to maintaining social engagement and continuity of mealtime activities were reported. In addition to nutritional benefit, family mealtimes provide important opportunities for persons with dementia and their family care partners to socially engage and continue meaningful roles. Strategies identified by participants provide a basis for further education and support to families living with dementia.

Stress and coping strategies in a sample of South African managers involved in post-graduate managerial studies

Directory of Open Access Journals (Sweden)

Judora J. Spangenberg

2000-06-01

Full Text Available To examine the relationships between stress levels and, respectively, stressor appraisal, coping strategies and bio- graphical variables, 107 managers completed a biographical questionnaire. Experience of Work and Life Circumstances Questionnaire, and Coping Strategy Indicator. Significant negative correlations were found between stress levels and appraisal scores on all work-related stressors. An avoidant coping strategy explained significant variance in stress levels in a model also containing social support-seeking and problem-solving coping strategies. It was concluded that an avoidant coping strategy probably contributed to increased stress levels. Female managers experienced significantly higher stress levels and utilized a social support-seeking coping strategy significantly more than male managers did. Opsomming Om die verband tussen stresvlakke en, onderskeidelik, taksering van stressors, streshanteringstrategiee en biografiese veranderlikes te ondersoek, het 107 bestuurders n biografiese vraelys, Ervaring vanWerk- en Lewensomstandighedevraelys en Streshanteringstrategieskaal voltooi. Beduidende negatiewe korrelasies is aangetref tussen stresvlakke en takseringtellings ten opsigte van alle werkverwante stressors. 'nVermydende streshantermgstrategie het beduidende variansie in stresvlakke verklaar in n model wat ook sosiale ondersteuningsoekende en pro-bleemoplossende streshanteringstrategiee ingesluit het. Die gevolgtrekking is bereik dat n vermydende stres- hanteringstrategie waarskynlik bygedra het tot verhoogde stresvlakke. Vroulike bestuurders het beduidend hoer stresvlakke ervaar en het n sosiale ondersteuningsoekende streshanteringstrategie beduidend meer gebnnk as manlike bestuurders.

Application of Quality Assurance Strategies in Diagnostics and Clinical Support Services in Iranian Hospitals

Science.gov (United States)

Aghaei Hashjin, Asgar; Kringos, Dionne; Ravaghi, Hamid; Manoochehri, Jila; Gorji, Hassan Abolghasem; Klazinga, Niek S.

2015-01-01

Background: Iran has a widespread diagnostics and clinical support services (DCSS) network that plays a crucial role in providing diagnostic and clinical support services to both inpatient and outpatient care. However, very little is known on the application of quality assurance (QA) policies in DCSS units. This study explores the extent of application of eleven QA strategies in DCSS units within Iranian hospitals and its association with hospital characteristics. Methods: A descriptive cross-sectional study was conducted in 2009/2010. Data were collected from 554 DCSS units among 84 hospitals. Results: The average reported application rate for the QA strategies ranged from 57%-94% in the DCSS units. Most frequently reported were checking drugs expiration dates (94%), pharmacopoeia availability (92%), equipment calibration (87%) and identifying responsibilities (86%). Least reported was external auditing of the DCSS (57%). The clinical chemistry and microbiology laboratories (84%), pharmacies, blood bank services (83%) reported highest average application rates across all questioned QA strategies. Lowest application rates were reported in human tissue banks (50%). There was no significant difference between the reported application rates in DCSS in the general/specialized, teaching/research, nonteaching/research hospitals with the exception of pharmacies and radiology departments. They reported availability of a written QA plan significantly more often in research hospitals. Nearly all QA strategies were reported to be applied significantly more often in the DCSS of Social Security Organization (SSO) and private-for-profit hospitals than in governmental hospitals. Conclusion: There is still room for strengthening the managerial cycle of QA systems and accountability in the DCSS in Iranian hospitals. Getting feedback, change and learning through application of specific QA strategies (eg, external/internal audits) can be improved. Both the effectiveness of QA

Application of Quality Assurance Strategies in Diagnostics and Clinical Support Services in Iranian Hospitals.

Science.gov (United States)

Aghaei Hashjin, Asgar; Kringos, Dionne; Ravaghi, Hamid; Manoochehri, Jila; Gorji, Hassan Abolghasem; Klazinga, Niek S

2015-05-20

Iran has a widespread diagnostics and clinical support services (DCSS) network that plays a crucial role in providing diagnostic and clinical support services to both inpatient and outpatient care. However, very little is known on the application of quality assurance (QA) policies in DCSS units. This study explores the extent of application of eleven QA strategies in DCSS units within Iranian hospitals and its association with hospital characteristics. A descriptive cross-sectional study was conducted in 2009/2010. Data were collected from 554 DCSS units among 84 hospitals. The average reported application rate for the QA strategies ranged from 57%-94% in the DCSS units. Most frequently reported were checking drugs expiration dates (94%), pharmacopoeia availability (92%), equipment calibration (87%) and identifying responsibilities (86%). Least reported was external auditing of the DCSS (57%). The clinical chemistry and microbiology laboratories (84%), pharmacies, blood bank services (83%) reported highest average application rates across all questioned QA strategies. Lowest application rates were reported in human tissue banks (50%). There was no significant difference between the reported application rates in DCSS in the general/specialized, teaching/research, nonteaching/research hospitals with the exception of pharmacies and radiology departments. They reported availability of a written QA plan significantly more often in research hospitals. Nearly all QA strategies were reported to be applied significantly more often in the DCSS of Social Security Organization (SSO) and private-for-profit hospitals than in governmental hospitals. There is still room for strengthening the managerial cycle of QA systems and accountability in the DCSS in Iranian hospitals. Getting feedback, change and learning through application of specific QA strategies (eg, external/internal audits) can be improved. Both the effectiveness of QA strategies in practice, and the application of

Application of Quality Assurance Strategies in Diagnostics and Clinical Support Services in Iranian Hospitals

Directory of Open Access Journals (Sweden)

Asgar Aghaei Hashjin

2015-10-01

Full Text Available Background Iran has a widespread diagnostics and clinical support services (DCSS network that plays a crucial role in providing diagnostic and clinical support services to both inpatient and outpatient care. However, very little is known on the application of quality assurance (QA policies in DCSS units. This study explores the extent of application of eleven QA strategies in DCSS units within Iranian hospitals and its association with hospital characteristics. Methods A descriptive cross-sectional study was conducted in 2009/2010. Data were collected from 554 DCSS units among 84 hospitals. Results The average reported application rate for the QA strategies ranged from 57%-94% in the DCSS units. Most frequently reported were checking drugs expiration dates (94%, pharmacopoeia availability (92%, equipment calibration (87% and identifying responsibilities (86%. Least reported was external auditing of the DCSS (57%. The clinical chemistry and microbiology laboratories (84%, pharmacies, blood bank services (83% reported highest average application rates across all questioned QA strategies. Lowest application rates were reported in human tissue banks (50%. There was no significant difference between the reported application rates in DCSS in the general/specialized, teaching/research, nonteaching/research hospitals with the exception of pharmacies and radiology departments. They reported availability of a written QA plan significantly more often in research hospitals. Nearly all QA strategies were reported to be applied significantly more often in the DCSS of Social Security Organization (SSO and private-for-profit hospitals than in governmental hospitals. Conclusion There is still room for strengthening the managerial cycle of QA systems and accountability in the DCSS in Iranian hospitals. Getting feedback, change and learning through application of specific QA strategies (eg, external/internal audits can be improved. Both the effectiveness of QA

Development of a sampling strategy and sample size calculation to estimate the distribution of mammographic breast density in Korean women.

Science.gov (United States)

Jun, Jae Kwan; Kim, Mi Jin; Choi, Kui Son; Suh, Mina; Jung, Kyu-Won

2012-01-01

Mammographic breast density is a known risk factor for breast cancer. To conduct a survey to estimate the distribution of mammographic breast density in Korean women, appropriate sampling strategies for representative and efficient sampling design were evaluated through simulation. Using the target population from the National Cancer Screening Programme (NCSP) for breast cancer in 2009, we verified the distribution estimate by repeating the simulation 1,000 times using stratified random sampling to investigate the distribution of breast density of 1,340,362 women. According to the simulation results, using a sampling design stratifying the nation into three groups (metropolitan, urban, and rural), with a total sample size of 4,000, we estimated the distribution of breast density in Korean women at a level of 0.01% tolerance. Based on the results of our study, a nationwide survey for estimating the distribution of mammographic breast density among Korean women can be conducted efficiently.

[The implementation of strategy of medicinal support in multi-type hospital].

Science.gov (United States)

Ludupova, E Yu

2016-01-01

The article presents brief review of implementation of strategy of medicinal support of population of the Russian Federation and experience of application of at the level of regional hospital. The necessity and importance of implementation into practice of hospitals of methodology of pharmaco-economical management of medicinal care using modern technologies of XYZ-, ABC and VEN-analysis is demonstrated. The stages of development and implementation of process of medicinal support of multifield hospital applying principles of system of quality management (processing and systemic approaches, risk management) on the basis of standards ISO 9001 are described. The significance of monitoring of results ofprocess of medicinal support of the basis of implementation of priority target programs (prevention of venous thrombo-embolic complications, system od control of anti-bacterial therapy) are demonstrated in relation to multi-field hospital using technique of ATC/DDD-analysis for evaluating indices of effectiveness and efficiency.

Limited sampling strategy for determining metformin area under the plasma concentration-time curve

DEFF Research Database (Denmark)

Santoro, Ana Beatriz; Stage, Tore Bjerregaard; Struchiner, Claudio José

2016-01-01

AIM: The aim was to develop and validate limited sampling strategy (LSS) models to predict the area under the plasma concentration-time curve (AUC) for metformin. METHODS: Metformin plasma concentrations (n = 627) at 0-24 h after a single 500 mg dose were used for LSS development, based on all su...

Energy modelling platforms for policy and strategy support

International Nuclear Information System (INIS)

Dyner, I.

2000-01-01

The energy field has been dominated by 'hard' modelling approaches by researchers from engineering and economics discipline. The recent trend towards a more liberalised environment moves away from central planning to market-based resource allocation, leading to the creation and use of strategic tools, with much 'softer' specifications, in the 'system-thinking' tradition. This paper presents the use of system dynamics in a generalised way, to provide a platform for integrated energy analysis. Issues of modularity and policy evolution are important in the design of the modelling platform to facilitate its use, and reuse. Hence the concepts of a platform, rather than a model, has to be implemented in a coherent way if it is to provide sustained value for ongoing support to both government policy and corporate strategy. (author)

Support for targeted sampling of red fox (Vulpes vulpes) feces in Sweden: a method to improve the probability of finding Echinococcus multilocularis.

Science.gov (United States)

Miller, Andrea L; Olsson, Gert E; Sollenberg, Sofia; Skarin, Moa; Wahlström, Helene; Höglund, Johan

2016-11-29

Localized concentrations of Echinococcus multilocularis eggs from feces of infected red fox (Vulpes vulpes) can create areas of higher transmission risk for rodent hosts and possibly also for humans; therefore, identification of these areas is important. However, in a low prevalence environment, such as Sweden, these areas could be easily overlooked. As part of a project investigating the role of different rodents in the epidemiology of E. multilocularis in Sweden, fox feces were collected seasonally from rodent trapping sites in two regions with known parasite status and in two regions with unknown parasite status, 2013-2015. The aim was to evaluate background contamination in rodent trapping sites from parasite eggs in these regions. To maximize the likelihood of finding fox feces positive for the parasite, fecal collection was focused in habitats with the assumed presence of suitable rodent intermediate hosts (i.e. targeted sampling). Parasite eggs were isolated from feces through sieving-flotation, and parasite species were then confirmed using PCR and sequencing. Most samples were collected in the late winter/early spring and in open fields where both Arvicola amphibius and Microtus agrestis were captured. Fox feces positive for E. multilocularis (41/714) were found within 1-3 field collection sites within each of the four regions. The overall proportion of positive samples was low (≤5.4%) in three regions, but was significantly higher in one region (22.5%, P < 0.001). There was not a significant difference between seasons or years. Compared to previous national screenings, our sampling strategy identified multiple E. multilocularis positive feces in all four regions, including the two regions with previously unknown parasite status. These results further suggest that the distribution of E. multilocularis is highly aggregated in the environment and provide support for further development of a targeted sampling strategy. Our results show that it was

NEA support to Fukushima Daiichi decommissioning strategy planning

International Nuclear Information System (INIS)

Weber, Inge; Otsuka, Ichiro; ); Sandberg, Nils; ); Funaki, Kentaro

2017-01-01

Six years after the Fukushima Daiichi nuclear power plant accident, the Japanese government and Tokyo Electric Power Holdings, Inc. (TEPCO) are shifting their focus to strategy planning for long-term challenges related to the decommissioning of the damaged reactors. The international community has been helping to address the unprecedented challenges of managing the accident facilities. The NEA is playing a key supporting and coordinating role in the international community, in particular in the area of radioactive waste management and the evaluation of the conditions and location of fuel debris. In the first half of 2017, a series of visual investigations using remotely controlled equipment and robots were performed to identify the condition of vessels inside, as well as the distribution of fuel debris in all three units. In the summer of 2017, as stated in the government road-map, policies for fuel debris retrieval from each unit would be presented, and would result in a discussion on which unit should be the first to undergo fuel debris retrieval in 2018. In addition, the basic policy for the processing and disposal of radioactive material arising from the accident would be conceptualised in the year 2017. This article highlights ongoing international joint activities within the NEA framework, corresponding to the challenges that have been identified in the Fukushima Daiichi decommissioning strategy planning

Population pharmacokinetic analysis of clopidogrel in healthy Jordanian subjects with emphasis optimal sampling strategy.

Science.gov (United States)

Yousef, A M; Melhem, M; Xue, B; Arafat, T; Reynolds, D K; Van Wart, S A

2013-05-01

Clopidogrel is metabolized primarily into an inactive carboxyl metabolite (clopidogrel-IM) or to a lesser extent an active thiol metabolite. A population pharmacokinetic (PK) model was developed using NONMEM(®) to describe the time course of clopidogrel-IM in plasma and to design a sparse-sampling strategy to predict clopidogrel-IM exposures for use in characterizing anti-platelet activity. Serial blood samples from 76 healthy Jordanian subjects administered a single 75 mg oral dose of clopidogrel were collected and assayed for clopidogrel-IM using reverse phase high performance liquid chromatography. A two-compartment (2-CMT) PK model with first-order absorption and elimination plus an absorption lag-time was evaluated, as well as a variation of this model designed to mimic enterohepatic recycling (EHC). Optimal PK sampling strategies (OSS) were determined using WinPOPT based upon collection of 3-12 post-dose samples. A two-compartment model with EHC provided the best fit and reduced bias in C(max) (median prediction error (PE%) of 9.58% versus 12.2%) relative to the basic two-compartment model, AUC(0-24) was similar for both models (median PE% = 1.39%). The OSS for fitting the two-compartment model with EHC required the collection of seven samples (0.25, 1, 2, 4, 5, 6 and 12 h). Reasonably unbiased and precise exposures were obtained when re-fitting this model to a reduced dataset considering only these sampling times. A two-compartment model considering EHC best characterized the time course of clopidogrel-IM in plasma. Use of the suggested OSS will allow for the collection of fewer PK samples when assessing clopidogrel-IM exposures. Copyright © 2013 John Wiley & Sons, Ltd.

Methodology Series Module 5: Sampling Strategies.

Science.gov (United States)

Setia, Maninder Singh

2016-01-01

Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the ' Sampling Method'. There are essentially two types of sampling methods: 1) probability sampling - based on chance events (such as random numbers, flipping a coin etc.); and 2) non-probability sampling - based on researcher's choice, population that accessible & available. Some of the non-probability sampling methods are: purposive sampling, convenience sampling, or quota sampling. Random sampling method (such as simple random sample or stratified random sample) is a form of probability sampling. It is important to understand the different sampling methods used in clinical studies and mention this method clearly in the manuscript. The researcher should not misrepresent the sampling method in the manuscript (such as using the term ' random sample' when the researcher has used convenience sample). The sampling method will depend on the research question. For instance, the researcher may want to understand an issue in greater detail for one particular population rather than worry about the ' generalizability' of these results. In such a scenario, the researcher may want to use ' purposive sampling' for the study.

Methodology series module 5: Sampling strategies

Directory of Open Access Journals (Sweden)

Maninder Singh Setia

2016-01-01

Full Text Available Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the 'Sampling Method'. There are essentially two types of sampling methods: 1 probability sampling – based on chance events (such as random numbers, flipping a coin etc.; and 2 non-probability sampling – based on researcher's choice, population that accessible & available. Some of the non-probability sampling methods are: purposive sampling, convenience sampling, or quota sampling. Random sampling method (such as simple random sample or stratified random sample is a form of probability sampling. It is important to understand the different sampling methods used in clinical studies and mention this method clearly in the manuscript. The researcher should not misrepresent the sampling method in the manuscript (such as using the term 'random sample' when the researcher has used convenience sample. The sampling method will depend on the research question. For instance, the researcher may want to understand an issue in greater detail for one particular population rather than worry about the 'generalizability' of these results. In such a scenario, the researcher may want to use 'purposive sampling' for the study.

Summary report on safety and licensing strategy support for the ABR prototype

International Nuclear Information System (INIS)

Cahalan, J. E.; Nuclear Engineering Division

2007-01-01

Argonne National Laboratory is providing support to the US Department of Energy in the Global Nuclear Energy Partnership (GNEP) in certification of an advanced, sodium-cooled fast reactor. The reactor is to be constructed as a prototype for future commercial power reactors that will produce electricity while consuming actinides recovered from light water reactor spent fuel. This prototype reactor has been called the Advanced Burner Reactor, or ABR, and is now often referred to as the advanced recycle reactor. As part of its activities, Argonne is providing technical services to assist definition of a safety and licensing strategy for the ABR prototype, and to further implementation of the strategy. In FY06, an organizational meeting was held for DOE and its laboratory contractors to discuss licensing alternatives and review previous licensing experience for the Fast Flux Test Facility (FFTF) and the Clinch River Breeder Reactor Plant (CRBRP). Near the end of FY06, a report summarizing the discussions and conclusions was written. One of the top-level conclusions recorded in the report was a recommendation to follow a licensing strategy that included the US Nuclear Regulatory Commission (NRC) as the regulatory review and licensing authority. In FY07, activities ar Argonne to support safety and licensing progress have continued. These activities have focused on further evaluation of licensing alternatives; assessment of design, analysis, and documentation implications of licensing paths; and initial technical interactions with the Nuclear Regulatory Commission. This report summarizes FY07 activities

Do parents of adolescents request the same universal parental support as parents of younger children? A random sample of Swedish parents.

Science.gov (United States)

Thorslund, Karin; Johansson Hanse, Jan; Axberg, Ulf

2017-07-01

Universal parental support intended to enhance parents' capacity for parenting is an important aspect of public health strategies. However, support has mostly been aimed at parents, especially mothers, of younger children. There is a gap in the research concerning parents of adolescents and fathers' interest in parenting support. To investigate and compare the interest in parenting support of parents of adolescents and younger children, potential differences between mothers and fathers, and their knowledge of what is being offered to them already, and to explore their requirements for future universal parental support. Telephone interviews were conducted with a random sample of 1336 parents. Quantitative methods were used to analyze differences between groups and qualitative methods were used to analyze open-ended questions in regard to parents' requirements for future universal parental support. About 82% of the parents of adolescents interviewed think that offering universal parental support is most important during child's adolescence. There is a substantial interest, particularly among mothers, in most forms of support. Despite their interest, parents have limited awareness of the support available. Only 7% knew about the local municipality website, although 70% reported a possible interest in such a website. Similarly, 3% knew that a parent phone line was available to them, while 59% reported a possible interest. It poses a challenge but is nevertheless important for municipalities to develop support targeted at parents of adolescents which is tailored to their needs, and to reach out with information.

Longitudinal relations among perceived autonomy support from health care practitioners, motivation, coping strategies and dietary compliance in a sample of adults with type 2 diabetes.

Science.gov (United States)

Julien, Etienne; Senécal, Caroline; Guay, Frédéric

2009-04-01

The purpose of this study was to test the causal ordering among perceived autonomy support from health care practitioners, motivation, coping strategies and compliance to dietary self-care activities. Using a cross-lagged panel model, we investigate how these variables relate to one another over a one-year period. A total of 365 adults with Type 2 diabetes participated in the study. Results suggest that autonomous motivation and active planning are reciprocally related over time, and that prior autonomous motivation is related to the extent participants subsequently comply with their diet. Results are discussed in light of Self-determination Theory and the coping perspective.

Methodology Series Module 5: Sampling Strategies

Science.gov (United States)

Setia, Maninder Singh

2016-01-01

Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the ‘ Sampling Method’. There are essentially two types of sampling methods: 1) probability sampling – based on chance events (such as random numbers, flipping a coin etc.); and 2) non-probability sampling – based on researcher's choice, population that accessible & available. Some of the non-probability sampling methods are: purposive sampling, convenience sampling, or quota sampling. Random sampling method (such as simple random sample or stratified random sample) is a form of probability sampling. It is important to understand the different sampling methods used in clinical studies and mention this method clearly in the manuscript. The researcher should not misrepresent the sampling method in the manuscript (such as using the term ‘ random sample’ when the researcher has used convenience sample). The sampling method will depend on the research question. For instance, the researcher may want to understand an issue in greater detail for one particular population rather than worry about the ‘ generalizability’ of these results. In such a scenario, the researcher may want to use ‘ purposive sampling’ for the study. PMID:27688438

A reexamination and extension of international strategy-structure theory

OpenAIRE

Wolf, Joachim; Egelhoff, William G.

2001-01-01

Using a sample of 95 German firms, the study finds general support for the traditional fits of international strategy-structure theory. Employing an information-processing perspective, the study conceptually and empirically extends existing theory (1) to address strategy-structure fit for various types of matrix structure, and (2) by adding two new elements of international strategy to the existing international strategy-structure model: the level of international transfers and level of forei...

Collaboration During the NASA ABoVE Airborne SAR Campaign: Sampling Strategies Used by NGEE Arctic and Other Partners in Alaska and Western Canada

Science.gov (United States)

Wullschleger, S. D.; Charsley-Groffman, L.; Baltzer, J. L.; Berg, A. A.; Griffith, P. C.; Jafarov, E. E.; Marsh, P.; Miller, C. E.; Schaefer, K. M.; Siqueira, P.; Wilson, C. J.; Kasischke, E. S.

2017-12-01

There is considerable interest in using L- and P-band Synthetic Aperture Radar (SAR) data to monitor variations in aboveground woody biomass, soil moisture, and permafrost conditions in high-latitude ecosystems. Such information is useful for quantifying spatial heterogeneity in surface and subsurface properties, and for model development and evaluation. To conduct these studies, it is desirable that field studies share a common sampling strategy so that the data from multiple sites can be combined and used to analyze variations in conditions across different landscape geomorphologies and vegetation types. In 2015, NASA launched the decade-long Arctic-Boreal Vulnerability Experiment (ABoVE) to study the sensitivity and resilience of these ecosystems to disturbance and environmental change. NASA is able to leverage its remote sensing strengths to collect airborne and satellite observations to capture important ecosystem properties and dynamics across large spatial scales. A critical component of this effort includes collection of ground-based data that can be used to analyze, calibrate and validate remote sensing products. ABoVE researchers at a large number of sites located in important Arctic and boreal ecosystems in Alaska and western Canada are following common design protocols and strategies for measuring soil moisture, thaw depth, biomass, and wetland inundation. Here we elaborate on those sampling strategies as used in the 2017 summer SAR campaign and address the sampling design and measurement protocols for supporting the ABoVE aerial activities. Plot size, transect length, and distribution of replicates across the landscape systematically allowed investigators to optimally sample a site for soil moisture, thaw depth, and organic layer thickness. Specific examples and data sets are described for the Department of Energy's Next-Generation Ecosystem Experiments (NGEE Arctic) project field sites near Nome and Barrow, Alaska. Future airborne and satellite

Comparison of sampling strategies for object-based classification of urban vegetation from Very High Resolution satellite images

Science.gov (United States)

Rougier, Simon; Puissant, Anne; Stumpf, André; Lachiche, Nicolas

2016-09-01

Vegetation monitoring is becoming a major issue in the urban environment due to the services they procure and necessitates an accurate and up to date mapping. Very High Resolution satellite images enable a detailed mapping of the urban tree and herbaceous vegetation. Several supervised classifications with statistical learning techniques have provided good results for the detection of urban vegetation but necessitate a large amount of training data. In this context, this study proposes to investigate the performances of different sampling strategies in order to reduce the number of examples needed. Two windows based active learning algorithms from state-of-art are compared to a classical stratified random sampling and a third combining active learning and stratified strategies is proposed. The efficiency of these strategies is evaluated on two medium size French cities, Strasbourg and Rennes, associated to different datasets. Results demonstrate that classical stratified random sampling can in some cases be just as effective as active learning methods and that it should be used more frequently to evaluate new active learning methods. Moreover, the active learning strategies proposed in this work enables to reduce the computational runtime by selecting multiple windows at each iteration without increasing the number of windows needed.

Recovery strategies implemented by sport support staff of elite rugby players in South Africa

Directory of Open Access Journals (Sweden)

D.V. Van Wyk

2009-01-01

Full Text Available Objective: The main aim of this study was to determine strategies used toaccelerate recovery of elite rugby players after training and matches, asused by medical support staff of rugby teams in South A frica. A  secondaryaim was to focus on specifics of implementing ice/cold water immersion asrecovery strategy. Design: A  Questionnaire-based cross sectional descriptive survey was used.Setting and Participants: Most (n=58 of the medical support staff ofrugby teams (doctors, physiotherapists, biokineticists and fitness trainerswho attended the inaugural Rugby Medical A ssociation conference linked to the South A frican Sports MedicineA ssociation Conference in Pretoria (14-16th November, 2007 participated in the study. Results: Recovery strategies were utilized mostly after matches. Stretching and ice/cold water immersion were utilized the most (83%. More biokineticists and fitness trainers advocated the usage of stretching than their counter-parts (medical doctors and physiotherapists. Ice/Cold water immersion and A ctive Recovery were the top two ratedstrategies. A  summary of the details around implementation of ice/cold water therapy is shown (mean as utilized bythe subjects: (i The time to immersion after matches was 12±9 min; (ii The total duration of one immersion sessionwas 6±6 min; (iii 3 immersion sessions per average training week was utilized by subjects; (iv The average water temperature was 10±3 ºC.; (v Ice cubes were used most frequently to cool water for immersion sessions, and(vi plastic drums were mostly used as the container for water. Conclusion: In this survey the representative group of support staff provided insight to which strategies are utilizedin South A frican elite rugby teams to accelerate recovery of players after training and/or matches.

A comparison of sample preparation strategies for biological tissues and subsequent trace element analysis using LA-ICP-MS.

Science.gov (United States)

Bonta, Maximilian; Török, Szilvia; Hegedus, Balazs; Döme, Balazs; Limbeck, Andreas

2017-03-01

Laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS) is one of the most commonly applied methods for lateral trace element distribution analysis in medical studies. Many improvements of the technique regarding quantification and achievable lateral resolution have been achieved in the last years. Nevertheless, sample preparation is also of major importance and the optimal sample preparation strategy still has not been defined. While conventional histology knows a number of sample pre-treatment strategies, little is known about the effect of these approaches on the lateral distributions of elements and/or their quantities in tissues. The technique of formalin fixation and paraffin embedding (FFPE) has emerged as the gold standard in tissue preparation. However, the potential use for elemental distribution studies is questionable due to a large number of sample preparation steps. In this work, LA-ICP-MS was used to examine the applicability of the FFPE sample preparation approach for elemental distribution studies. Qualitative elemental distributions as well as quantitative concentrations in cryo-cut tissues as well as FFPE samples were compared. Results showed that some metals (especially Na and K) are severely affected by the FFPE process, whereas others (e.g., Mn, Ni) are less influenced. Based on these results, a general recommendation can be given: FFPE samples are completely unsuitable for the analysis of alkaline metals. When analyzing transition metals, FFPE samples can give comparable results to snap-frozen tissues. Graphical abstract Sample preparation strategies for biological tissues are compared with regard to the elemental distributions and average trace element concentrations.

Strategies to Support PGCE Mathematics and Science Students Preparing for Assignments at Masters Level

OpenAIRE

Tas, Maarten; Forsythe, Sue

2010-01-01

The main aim of this study was to analyse and evaluate the effectiveness of support strategies being put into place for students who need to write assignments at Masters Level. In preparation for writing a 5000 word assignment on an aspect of teaching Mathematics or Science, 57 Science and Mathematics PGCE students were asked to write a 500 word synopsis which included an introduction, description of the main focus, questions that the assignment would address and possible strategies for teach...

An Experience Sampling Study of Learning, Affect, and the Demands Control Support Model

Science.gov (United States)

Daniels, Kevin; Boocock, Grahame; Glover, Jane; Hartley, Ruth; Holland, Julie

2009-01-01

The demands control support model (R. A. Karasek & T. Theorell, 1990) indicates that job control and social support enable workers to engage in problem solving. In turn, problem solving is thought to influence learning and well-being (e.g., anxious affect, activated pleasant affect). Two samples (N = 78, N = 106) provided data up to 4 times per…

Optimization of Region-of-Interest Sampling Strategies for Hepatic MRI Proton Density Fat Fraction Quantification

Science.gov (United States)

Hong, Cheng William; Wolfson, Tanya; Sy, Ethan Z.; Schlein, Alexandra N.; Hooker, Jonathan C.; Dehkordy, Soudabeh Fazeli; Hamilton, Gavin; Reeder, Scott B.; Loomba, Rohit; Sirlin, Claude B.

2017-01-01

BACKGROUND Clinical trials utilizing proton density fat fraction (PDFF) as an imaging biomarker for hepatic steatosis have used a laborious region-of-interest (ROI) sampling strategy of placing an ROI in each hepatic segment. PURPOSE To identify a strategy with the fewest ROIs that consistently achieves close agreement with the nine-ROI strategy. STUDY TYPE Retrospective secondary analysis of prospectively acquired clinical research data. POPULATION A total of 391 adults (173 men, 218 women) with known or suspected NAFLD. FIELD STRENGTH/SEQUENCE Confounder-corrected chemical-shift-encoded 3T MRI using a 2D multiecho gradientrecalled echo technique. ASSESSMENT An ROI was placed in each hepatic segment. Mean nine-ROI PDFF and segmental PDFF standard deviation were computed. Segmental and lobar PDFF were compared. PDFF was estimated using every combinatorial subset of ROIs and compared to the nine-ROI average. STATISTICAL TESTING Mean nine-ROI PDFF and segmental PDFF standard deviation were summarized descriptively. Segmental PDFF was compared using a one-way analysis of variance, and lobar PDFF was compared using a paired t-test and a Bland–Altman analysis. The PDFF estimated by every subset of ROIs was informally compared to the nine-ROI average using median intraclass correlation coefficients (ICCs) and Bland–Altman analyses. RESULTS The study population’s mean whole-liver PDFF was 10.1±8.9% (range: 1.1–44.1%). Although there was no significant difference in average segmental (P=0.452) or lobar (P=0.154) PDFF, left and right lobe PDFF differed by at least 1.5 percentage points in 25.1% (98/391) of patients. Any strategy with ≥ 4 ROIs had ICC >0.995. 115 of 126 four-ROI strategies (91%) had limits of agreement (LOA) 0.995, and 2/36 (6%) of two-ROI strategies and 46/84 (55%) of three-ROI strategies had LOA <1.5%. DATA CONCLUSION Four-ROI sampling strategies with two ROIs in the left and right lobes achieve close agreement with nine-ROI PDFF. Level of

Optimization of region-of-interest sampling strategies for hepatic MRI proton density fat fraction quantification.

Science.gov (United States)

Hong, Cheng William; Wolfson, Tanya; Sy, Ethan Z; Schlein, Alexandra N; Hooker, Jonathan C; Fazeli Dehkordy, Soudabeh; Hamilton, Gavin; Reeder, Scott B; Loomba, Rohit; Sirlin, Claude B

2018-04-01

Clinical trials utilizing proton density fat fraction (PDFF) as an imaging biomarker for hepatic steatosis have used a laborious region-of-interest (ROI) sampling strategy of placing an ROI in each hepatic segment. To identify a strategy with the fewest ROIs that consistently achieves close agreement with the nine-ROI strategy. Retrospective secondary analysis of prospectively acquired clinical research data. A total of 391 adults (173 men, 218 women) with known or suspected NAFLD. Confounder-corrected chemical-shift-encoded 3T MRI using a 2D multiecho gradient-recalled echo technique. An ROI was placed in each hepatic segment. Mean nine-ROI PDFF and segmental PDFF standard deviation were computed. Segmental and lobar PDFF were compared. PDFF was estimated using every combinatorial subset of ROIs and compared to the nine-ROI average. Mean nine-ROI PDFF and segmental PDFF standard deviation were summarized descriptively. Segmental PDFF was compared using a one-way analysis of variance, and lobar PDFF was compared using a paired t-test and a Bland-Altman analysis. The PDFF estimated by every subset of ROIs was informally compared to the nine-ROI average using median intraclass correlation coefficients (ICCs) and Bland-Altman analyses. The study population's mean whole-liver PDFF was 10.1 ± 8.9% (range: 1.1-44.1%). Although there was no significant difference in average segmental (P = 0.452) or lobar (P = 0.154) PDFF, left and right lobe PDFF differed by at least 1.5 percentage points in 25.1% (98/391) of patients. Any strategy with ≥4 ROIs had ICC >0.995. 115 of 126 four-ROI strategies (91%) had limits of agreement (LOA) 0.995, and 2/36 (6%) of two-ROI strategies and 46/84 (55%) of three-ROI strategies had LOA <1.5%. Four-ROI sampling strategies with two ROIs in the left and right lobes achieve close agreement with nine-ROI PDFF. 3 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018;47:988-994. © 2017 International Society for Magnetic Resonance

A systematic examination of a random sampling strategy for source apportionment calculations.

Science.gov (United States)

Andersson, August

2011-12-15

Estimating the relative contributions from multiple potential sources of a specific component in a mixed environmental matrix is a general challenge in diverse fields such as atmospheric, environmental and earth sciences. Perhaps the most common strategy for tackling such problems is by setting up a system of linear equations for the fractional influence of different sources. Even though an algebraic solution of this approach is possible for the common situation with N+1 sources and N source markers, such methodology introduces a bias, since it is implicitly assumed that the calculated fractions and the corresponding uncertainties are independent of the variability of the source distributions. Here, a random sampling (RS) strategy for accounting for such statistical bias is examined by investigating rationally designed synthetic data sets. This random sampling methodology is found to be robust and accurate with respect to reproducibility and predictability. This method is also compared to a numerical integration solution for a two-source situation where source variability also is included. A general observation from this examination is that the variability of the source profiles not only affects the calculated precision but also the mean/median source contributions. Copyright © 2011 Elsevier B.V. All rights reserved.

Examining Masculine Norms and Peer Support within a Sample of Incarcerated African American Males.

Science.gov (United States)

Gordon, Derrick M; Hawes, Samuel W; Perez-Cabello, M Arturo; Brabham-Hollis, Tamika; Lanza, A Stephen; Dyson, William J

2013-01-01

The adherence to masculine norms has been suggested to be influenced by social settings and context. Prisons have been described as a context where survival is dependent on adhering to strict masculine norms that may undermine reintegration back into the larger society. This study attempted to examine the relationship between masculine norms, peer support, and an individual's length of incarceration on a sample of 139 African American men taking part in a pre-release community re-entry program. Results indicate that peer support was associated with length of incarceration and the interaction between the endorsement of masculine norms and peer support significantly predicted the length of incarceration for African American men in this sample. Implications for incarcerated African American men and future research directions are discussed.

REECo activities and sample logistics in support of the Nevada Applied Ecology Group

International Nuclear Information System (INIS)

Wireman, D.L.; Rosenberry, C.E. Jr.

1975-01-01

Activities and sample logistics of Reynolds Electrical and Engineering Co., Inc. (REECo), in support of the Nevada Applied Ecology Group (NAEG), are discussed in this summary report. Activities include the collection, preparation, and shipment of samples of soils, vegetation, and small animals collected at Pu-contaminated areas of the Nevada Test Site and Tonopah Test Range. (CH)

Analytical sample preparation strategies for the determination of antimalarial drugs in human whole blood, plasma and urine

DEFF Research Database (Denmark)

Casas, Monica Escolà; Hansen, Martin; Krogh, Kristine A

2014-01-01

the available sample preparation strategies combined with liquid chromatographic (LC) analysis to determine antimalarials in whole blood, plasma and urine published over the last decade. Sample preparation can be done by protein precipitation, solid-phase extraction, liquid-liquid extraction or dilution. After...

Strategies for successful academic writing - institutional and non-institutional support for students.

Science.gov (United States)

Gopee, Neil; Deane, Mary

2013-12-01

Students develop better academic writing skills as they progress through their higher education programme, but despite recent continuing monitoring of student satisfaction with their education in UK, there has been relatively little research into students' perceptions of the active support that they need and receive to succeed as academic writers. To examine the strategies that university students on health or social care courses utilise to develop as writers in the face of many pressures and demands from different sources. Qualitative research conducted at a British University into undergraduates' writing practices in the field of healthcare. Ten participants took part in semi-structured interviews, half of whom were international students. The data was analysed by the researchers from the field of writing development using thematic analysis. The main findings are that certain students struggle as academic writers if they do not receive tuition on appropriate and effective academic writing through institutional provisions, or through non-institutional strategies, that can promote success with the writing process. There is also uncertainty over the extent to which nurse educators are expected to teach academic writing skills, alongside their discipline-specific subject areas. Both institutional provisions for academic writing development, such as a dedicated writing support department, and non-institutional factors such as peer-collaboration should be fully recognised, supported and resourced in tertiary education at a time when students' satisfaction and performance are high on the agenda. Copyright © 2012 Elsevier Ltd. All rights reserved.

Fault Diagnosis in Condition of Sample Type Incompleteness Using Support Vector Data Description

Directory of Open Access Journals (Sweden)

Hui Yi

2015-01-01

Full Text Available Faulty samples are much harder to acquire than normal samples, especially in complicated systems. This leads to incompleteness for training sample types and furthermore a decrease of diagnostic accuracy. In this paper, the relationship between sample-type incompleteness and the classifier-based diagnostic accuracy is discussed first. Then, a support vector data description-based approach, which has taken the effects of sample-type incompleteness into consideration, is proposed to refine the construction of fault regions and increase the diagnostic accuracy for the condition of incomplete sample types. The effectiveness of the proposed method was validated on both a Gaussian distributed dataset and a practical dataset. Satisfactory results have been obtained.

Current advances and strategies towards fully automated sample preparation for regulated LC-MS/MS bioanalysis.

Science.gov (United States)

Zheng, Naiyu; Jiang, Hao; Zeng, Jianing

2014-09-01

Robotic liquid handlers (RLHs) have been widely used in automated sample preparation for liquid chromatography-tandem mass spectrometry (LC-MS/MS) bioanalysis. Automated sample preparation for regulated bioanalysis offers significantly higher assay efficiency, better data quality and potential bioanalytical cost-savings. For RLHs that are used for regulated bioanalysis, there are additional requirements, including 21 CFR Part 11 compliance, software validation, system qualification, calibration verification and proper maintenance. This article reviews recent advances in automated sample preparation for regulated bioanalysis in the last 5 years. Specifically, it covers the following aspects: regulated bioanalysis requirements, recent advances in automation hardware and software development, sample extraction workflow simplification, strategies towards fully automated sample extraction, and best practices in automated sample preparation for regulated bioanalysis.

New sampling strategy using a Bayesian approach to assess iohexol clearance in kidney transplant recipients.

Science.gov (United States)

Benz-de Bretagne, I; Le Guellec, C; Halimi, J M; Gatault, P; Barbet, C; Alnajjar, A; Büchler, M; Lebranchu, Y; Andres, Christian Robert; Vourcʼh, P; Blasco, H

2012-06-01

Glomerular filtration rate (GFR) measurement is a major issue in kidney transplant recipients for clinicians. GFR can be determined by estimating the plasma clearance of iohexol, a nonradiolabeled compound. For practical and convenient application for patients and caregivers, it is important that a minimal number of samples are drawn. The aim of this study was to develop and validate a Bayesian model with fewer samples for reliable prediction of GFR in kidney transplant recipients. Iohexol plasma concentration-time curves from 95 patients were divided into an index (n = 63) and a validation set (n = 32). Samples (n = 4-6 per patient) were obtained during the elimination phase, that is, between 120 and 270 minutes. Individual reference values of iohexol clearance (CL(iohexol)) were calculated from k (elimination slope) and V (volume of distribution from intercept). Individual CL(iohexol) values were then introduced into the Bröchner-Mortensen equation to obtain the GFR (reference value). A population pharmacokinetic model was developed from the index set and validated using standard methods. For the validation set, we tested various combinations of 1, 2, or 3 sampling time to estimate CL(iohexol). According to the different combinations tested, a maximum a posteriori Bayesian estimation of CL(iohexol) was obtained from population parameters. Individual estimates of GFR were compared with individual reference values through analysis of bias and precision. A capability analysis allowed us to determine the best sampling strategy for Bayesian estimation. A 1-compartment model best described our data. Covariate analysis showed that uremia, serum creatinine, and age were significantly associated with k(e), and weight with V. The strategy, including samples drawn at 120 and 270 minutes, allowed accurate prediction of GFR (mean bias: -3.71%, mean imprecision: 7.77%). With this strategy, about 20% of individual predictions were outside the bounds of acceptance set at ± 10

Alcohol-related crime in city entertainment precincts: Public perception and experience of alcohol-related crime and support for strategies to reduce such crime.

Science.gov (United States)

Tindall, Jenny; Groombridge, Daniel; Wiggers, John; Gillham, Karen; Palmer, Darren; Clinton-McHarg, Tara; Lecathelinais, Christophe; Miller, Peter

2016-05-01

Bars, pubs and taverns in cities are often concentrated in entertainment precincts that are associated with higher rates of alcohol-related crime. This study assessed public perception and experiences of such crime in two city entertainment precincts, and support for alcohol-related crime reduction strategies. A cross-sectional household telephone survey in two Australian regions assessed: perception and experiences of crime; support for crime reduction strategies; and differences in such perceptions and support. Six hundred ninety-four people completed the survey (32%). Most agreed that alcohol was a problem in their entertainment precinct (90%) with violence the most common alcohol-related problem reported (97%). Almost all crime reduction strategies were supported by more than 50% of participants, including visitors to the entertainment precincts, with the latter being slightly less likely to support earlier closing and restrictions on premises density. Participants in one region were more likely to support earlier closing and lock-out times. Those at-risk of acute alcohol harm were less likely to support more restrictive policies. High levels of community concern and support for alcohol harm-reduction strategies, including restrictive strategies, provide policy makers with a basis for implementing evidence-based strategies to reduce such harms in city entertainment precincts. [Tindall J, Groombridge D, Wiggers J, Gillham K, Palmer D, Clinton-McHarg T, Lecathelinais C, Miller P. Alcohol-related crime in city entertainment precincts: Public perception and experience of alcohol-related crime and support for strategies to reduce such crime. Drug Alcohol Rev 2016;35:263-272]. © 2015 The Authors. Drug and Alcohol Review published by Wiley Publishing Asia Pty Ltd on behalf of Australasian Professional Society on Alcohol and other Drugs.

A simulation approach to assessing sampling strategies for insect pests: an example with the balsam gall midge.

Directory of Open Access Journals (Sweden)

R Drew Carleton

Full Text Available Estimation of pest density is a basic requirement for integrated pest management in agriculture and forestry, and efficiency in density estimation is a common goal. Sequential sampling techniques promise efficient sampling, but their application can involve cumbersome mathematics and/or intensive warm-up sampling when pests have complex within- or between-site distributions. We provide tools for assessing the efficiency of sequential sampling and of alternative, simpler sampling plans, using computer simulation with "pre-sampling" data. We illustrate our approach using data for balsam gall midge (Paradiplosis tumifex attack in Christmas tree farms. Paradiplosis tumifex proved recalcitrant to sequential sampling techniques. Midge distributions could not be fit by a common negative binomial distribution across sites. Local parameterization, using warm-up samples to estimate the clumping parameter k for each site, performed poorly: k estimates were unreliable even for samples of n ∼ 100 trees. These methods were further confounded by significant within-site spatial autocorrelation. Much simpler sampling schemes, involving random or belt-transect sampling to preset sample sizes, were effective and efficient for P. tumifex. Sampling via belt transects (through the longest dimension of a stand was the most efficient, with sample means converging on true mean density for sample sizes of n ∼ 25-40 trees. Pre-sampling and simulation techniques provide a simple method for assessing sampling strategies for estimating insect infestation. We suspect that many pests will resemble P. tumifex in challenging the assumptions of sequential sampling methods. Our software will allow practitioners to optimize sampling strategies before they are brought to real-world applications, while potentially avoiding the need for the cumbersome calculations required for sequential sampling methods.

A Successful Implementation Strategy to Support Adoption of Decision Making in Mental Health Services.

Science.gov (United States)

MacDonald-Wilson, Kim L; Hutchison, Shari L; Karpov, Irina; Wittman, Paul; Deegan, Patricia E

2017-04-01

Individual involvement in treatment decisions with providers, often through the use of decision support aids, improves quality of care. This study investigates an implementation strategy to bring decision support to community mental health centers (CMHC). Fifty-two CMHCs implemented a decision support toolkit supported by a 12-month learning collaborative using the Breakthrough Series model. Participation in learning collaborative activities was high, indicating feasibility of the implementation model. Progress by staff in meeting process aims around utilization of components of the toolkit improved significantly over time (p < .0001). Survey responses by individuals in service corroborate successful implementation. Community-based providers were able to successfully implement decision support in mental health services as evidenced by improved process outcomes and sustained practices over 1 year through the structure of the learning collaborative model.

Gender, social support, and well-being: Evidence from a Greek community sample

Directory of Open Access Journals (Sweden)

Konstantinos Kafetsios

2007-12-01

Full Text Available The importance of social support for psychological well-being has been aptly highlighted in epidemiological and psychological research. However, it is not clear from the existing research whether gender differences in structural (relationship status, network size, frequency of interactions with friends and functional (support satisfaction aspects of social support exist and -if they do- to what extent they affect males’ and females’ well-being. Hierarchical regression analyses of crossectional data from a Greek community sample showed that support satisfaction was an important predictor of well-being outcomes in males whereas several structural indicators were predictors of different well-being outcomes in females. Females’ anxiety, perceived stress, and loneliness were adversely affected by frequency of interaction with acquaintances. The results are discussed with regard to gender-role differences that may be underlying the social support effects on well-being, as well as related cultural values.

Social competence of elementary-school children: relationships to maternal authoritativeness, supportive maternal responses and children's coping strategies.

Science.gov (United States)

Chan, S M

2011-07-01

Although the influences of parenting on children's development of social competence have been well established, research on the underlying mechanisms of this link is relatively limited. The present study examined children's coping strategies as a mediator of the effects of maternal authoritativeness and maternal inductive responses on their social competence. The mothers of 183 Hong Kong Chinese children aged 6 to 8 years (89 girls and 94 boys) reported on their adoption of authoritative parenting and their responses to their children's expressions of emotion, and rated their children's adoption of constructive coping strategies. The children's teachers reported on the children's prosocial behaviour, and rated their level of peer acceptance at school. A model of maternal authoritativeness and supportive maternal responses affecting children's social competence is presented. The study results show that the effects of authoritative parenting on children's adoption of constructive coping strategies were mediated by supportive maternal responses to children's expression of emotion, and that the effects of maternal authoritativeness and maternal responses on children's social competence were mediated by children's coping strategies. These results suggest that school personnel should organize training programmes on emotion-coping strategies for both parents and children. The findings imply that positive parenting facilitates children's acquisition of constructive emotion-coping strategies. Programmes on emotion-coping strategies should be introduced for both parents and school children. © 2011 Blackwell Publishing Ltd.

External calibration strategy for trace element quantification in botanical samples by LA-ICP-MS using filter paper

International Nuclear Information System (INIS)

Nunes, Matheus A.G.; Voss, Mônica; Corazza, Gabriela; Flores, Erico M.M.; Dressler, Valderi L.

2016-01-01

The use of reference solutions dispersed on filter paper discs is proposed for the first time as an external calibration strategy for matrix matching and determination of As, Cd, Co, Cr, Cu, Mn, Ni, Pb, Sr, V and Zn in plants by laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS). The procedure is based on the use of filter paper discs as support for aqueous reference solutions, which are further evaporated, resulting in solid standards with concentrations up to 250 μg g −1 of each element. The use of filter paper for calibration is proposed as matrix matched standards due to the similarities of this material with botanical samples, regarding to carbon concentration and its distribution through both matrices. These characteristics allowed the use of 13 C as internal standard (IS) during the analysis by LA-ICP-MS. In this way, parameters as analyte signal normalization with 13 C, carrier gas flow rate, laser energy, spot size, and calibration range were monitored. The calibration procedure using solution deposition on filter paper discs resulted in precision improvement when 13 C was used as IS. The method precision was calculated by the analysis of a certified reference material (CRM) of botanical matrix, considering the RSD obtained for 5 line scans and was lower than 20%. Accuracy of LA-ICP-MS determinations were evaluated by analysis of four CRM pellets of botanical composition, as well as by comparison with results obtained by ICP-MS using solution nebulization after microwave assisted digestion. Plant samples of unknown elemental composition were analyzed by the proposed LA method and good agreement were obtained with results of solution analysis. Limits of detection (LOD) established for LA-ICP-MS were obtained by the ablation of 10 lines on the filter paper disc containing 40 μL of 5% HNO 3 (v v −1 ) as calibration blank. Values ranged from 0.05 to 0.81  μg g −1 . Overall, the use of filter paper as support for dried

External calibration strategy for trace element quantification in botanical samples by LA-ICP-MS using filter paper

Energy Technology Data Exchange (ETDEWEB)

Nunes, Matheus A.G.; Voss, Mônica; Corazza, Gabriela; Flores, Erico M.M.; Dressler, Valderi L., E-mail: vdressler@gmail.com

2016-01-28

The use of reference solutions dispersed on filter paper discs is proposed for the first time as an external calibration strategy for matrix matching and determination of As, Cd, Co, Cr, Cu, Mn, Ni, Pb, Sr, V and Zn in plants by laser ablation-inductively coupled plasma mass spectrometry (LA-ICP-MS). The procedure is based on the use of filter paper discs as support for aqueous reference solutions, which are further evaporated, resulting in solid standards with concentrations up to 250 μg g{sup −1} of each element. The use of filter paper for calibration is proposed as matrix matched standards due to the similarities of this material with botanical samples, regarding to carbon concentration and its distribution through both matrices. These characteristics allowed the use of {sup 13}C as internal standard (IS) during the analysis by LA-ICP-MS. In this way, parameters as analyte signal normalization with {sup 13}C, carrier gas flow rate, laser energy, spot size, and calibration range were monitored. The calibration procedure using solution deposition on filter paper discs resulted in precision improvement when {sup 13}C was used as IS. The method precision was calculated by the analysis of a certified reference material (CRM) of botanical matrix, considering the RSD obtained for 5 line scans and was lower than 20%. Accuracy of LA-ICP-MS determinations were evaluated by analysis of four CRM pellets of botanical composition, as well as by comparison with results obtained by ICP-MS using solution nebulization after microwave assisted digestion. Plant samples of unknown elemental composition were analyzed by the proposed LA method and good agreement were obtained with results of solution analysis. Limits of detection (LOD) established for LA-ICP-MS were obtained by the ablation of 10 lines on the filter paper disc containing 40 μL of 5% HNO{sub 3} (v v{sup −1}) as calibration blank. Values ranged from 0.05 to 0.81  μg g{sup −1}. Overall, the use of filter

JRC GMO-Matrix: a web application to support Genetically Modified Organisms detection strategies.

Science.gov (United States)

Angers-Loustau, Alexandre; Petrillo, Mauro; Bonfini, Laura; Gatto, Francesco; Rosa, Sabrina; Patak, Alexandre; Kreysa, Joachim

2014-12-30

The polymerase chain reaction (PCR) is the current state of the art technique for DNA-based detection of Genetically Modified Organisms (GMOs). A typical control strategy starts by analyzing a sample for the presence of target sequences (GM-elements) known to be present in many GMOs. Positive findings from this "screening" are then confirmed with GM (event) specific test methods. A reliable knowledge of which GMOs are detected by combinations of GM-detection methods is thus crucial to minimize the verification efforts. In this article, we describe a novel platform that links the information of two unique databases built and maintained by the European Union Reference Laboratory for Genetically Modified Food and Feed (EU-RL GMFF) at the Joint Research Centre (JRC) of the European Commission, one containing the sequence information of known GM-events and the other validated PCR-based detection and identification methods. The new platform compiles in silico determinations of the detection of a wide range of GMOs by the available detection methods using existing scripts that simulate PCR amplification and, when present, probe binding. The correctness of the information has been verified by comparing the in silico conclusions to experimental results for a subset of forty-nine GM events and six methods. The JRC GMO-Matrix is unique for its reliance on DNA sequence data and its flexibility in integrating novel GMOs and new detection methods. Users can mine the database using a set of web interfaces that thus provide a valuable support to GMO control laboratories in planning and evaluating their GMO screening strategies. The platform is accessible at http://gmo-crl.jrc.ec.europa.eu/jrcgmomatrix/ .

Methodology Series Module 5: Sampling Strategies

OpenAIRE

Setia, Maninder Singh

2016-01-01

Once the research question and the research design have been finalised, it is important to select the appropriate sample for the study. The method by which the researcher selects the sample is the ? Sampling Method?. There are essentially two types of sampling methods: 1) probability sampling ? based on chance events (such as random numbers, flipping a coin etc.); and 2) non-probability sampling ? based on researcher's choice, population that accessible & available. Some of the non-probabilit...

A Communication-Supported Comprehensive Protection Strategy for Converter-Interfaced Islanded Microgrids

Directory of Open Access Journals (Sweden)

Dehua Zheng

2018-04-01

Full Text Available The deployment of distributed generators (DGs gives rise to several challenges for a microgrid or conventional distribution feeder, regarding control and protection issues. The major ones are: bi-directional flow of power, changes in fault current magnitude, and continuous changes in operational configuration due to both the plug-and-play of DGs and loads, and the intermittency of the renewable DGs. This issue is exacerbated when the microgrid contains several converter-interfaced DGs and operates in the islanded mode of operation. Hence, conventional protection strategies and relaying techniques will no longer be sufficient to protect islanded microgrids against network faults and disturbance conditions. This paper proposes a fast and reliable communication-supported protection strategy for ensuring the safe operation of converter-interfaced islanded microgrids. The strategy is implementable using commercially accessible microprocessor based digital relays, and is applicable for the protection of low voltage islanded microgrids. It provides backup protection to handle communication failures and malfunctions of protective devices. The paper also presents the detailed structural layout of the digital relay, which executes the proposed protection strategy. A number of improvements are proposed to find an alternative method for conventional overcurrent relays to reliably detect small-magnitude fault currents and high impedance faults, commonly encountered in converter-interfaced islanded microgrids. A simple and economical bus protection method is also proposed. Several simulations are conducted on a comprehensive model of a realistic operational industrial microgrid (Goldwind Smart Microgrid System using PSCAD/EMTDC software environment—for different case studies and fault scenarios—to verify the effectiveness of the present strategy and its digital relay.

Clinical Decision Support Knowledge Management: Strategies for Success.

Science.gov (United States)

Khalifa, Mohamed; Alswailem, Osama

2015-01-01

Clinical Decision Support Systems have been shown to increase quality of care, patient safety, improve adherence to guidelines for prevention and treatment, and avoid medication errors. Such systems depend mainly on two types of content; the clinical information related to patients and the medical knowledge related to the specialty that informs the system rules and alerts. At King Faisal Specialist Hospital and Research Center, Saudi Arabia, the Health Information Technology Affairs worked on identifying best strategies and recommendations for successful CDSS knowledge management. A review of literature was conducted to identify main areas of challenges and factors of success. A qualitative survey was used over six months' duration to collect opinions, experiences and suggestions from both IT and healthcare professionals. Recommendations were categorized into ten main topics that should be addressed during the development and implementation of CDSS knowledge management tools in the hospital.

Interfacial charge distributions in carbon-supported palladium catalysts

DEFF Research Database (Denmark)

Rao, Radhika G.; Blume, Raoul; Hansen, Thomas Willum

2017-01-01

Controlling the charge transfer between a semiconducting catalyst carrier and the supported transition metal active phase represents an elite strategy for fine turning the electronic structure of the catalytic centers, hence their activity and selectivity. These phenomena have been theoretically...... and experimentally elucidated for oxide supports but remain poorly understood for carbons due to their complex nanoscale structure. Here, we combine advanced spectroscopy and microscopy on model Pd/C samples to decouple the electronic and surface chemistry effects on catalytic performance. Our investigations reveal...... treatments can be used to tune the interfacial charge distribution, hereby providing a strategy to rationally design carbon-supported catalysts.Control over charge transfer in carbon-supported metal nanoparticles is essential for designing new catalysts. Here, the authors show that thermal treatments...

Social supports and prevention strategies as adjuncts and alternatives to sedation and anesthesia for people with special needs.

Science.gov (United States)

Glassman, Paul; Miller, Christine

2009-01-01

People with special needs are assuming a more prominent place in our society. The number of people living in communities with medical, physical, and psychological conditions is increasing dramatically. In spite of the advances that people with special needs have made in recognition of their right to live in society and access services open to other people, their oral health is still significantly poorer than that of other groups. There are a number of modalities that can complement or replace pharmacological interventions and allow individuals to have dental treatment in a dental office or clinic. These include behavioral or psychological interventions and social support and prevention strategies. Social supports include care management and integration of oral health services with general health and social service systems. Preventive programs using modern "medical model" oral health prevention strategies also have the potential to reduce the burden of disease among people with special needs and therefore reduce the need for dental procedures. A social support system using community-based Dental Hygienists acting as Dental Coordinators, is described along with outcomes demonstrating improved oral health for people with special needs living in community residential care facilities. Combined social support systems and community prevention strategies have the potential to reduce the need for pharmacological interventions in order to maintain oral health in populations of people with special needs. Social supports and modern preventive strategies must be included in the range of options available in communities in order to improve and maintain oral health for people with special needs.

KNOWLEDGE MANAGEMENT IN MALAYSIAN SMEs: AN EMPIRICAL EXAMINATION ON INFORMATION TECHNOLOGY (IT) SUPPORT AND STRATEGY AS PLAN

OpenAIRE

Tan Thai Soon; Fakhrul Anwar Zainol

2011-01-01

This research study demonstrates the important of the knowledge creation process. It helps to demonstrate that knowledge management enablers, including IT-support and Strategy as Plan can promote organizational creativity and thus organizational performance. Further, the findings on the new factor, Strategy as Plan, show that it is positively related to knowledge creation. Strategy as Plan can therefore be regarded as an integral part of knowledge creation. This reaffirms Glueck’s (1980, p.9)...

Effects of the teach-model-coach-review instructional approach on caregiver use of language support strategies and children's expressive language skills.

Science.gov (United States)

Roberts, Megan Y; Kaiser, Ann P; Wolfe, Cathy E; Bryant, Julie D; Spidalieri, Alexandria M

2014-10-01

In this study, the authors examined the effects of the Teach-Model-Coach-Review instructional approach on caregivers' use of four enhanced milieu teaching (EMT) language support strategies and on their children's use of expressive language. Four caregiver-child dyads participated in a single-subject, multiple-baseline study. Children were between 24 and 42 months of age and had language impairment. Interventionists used the Teach-Model-Coach-Review instructional approach to teach caregivers to use matched turns, expansions, time delays, and milieu teaching prompts during 24 individualized clinic sessions. Caregiver use of each EMT language support strategy and child use of communication targets were the dependent variables. The caregivers demonstrated increases in their use of each EMT language support strategy after instruction. Generalization and maintenance of strategy use to the home was limited, indicating that teaching across routines is necessary to achieve maximal outcomes. All children demonstrated gains in their use of communication targets and in their performance on norm-referenced measures of language. The results indicate that the Teach-Model-Coach-Review instructional approach resulted in increased use of EMT language support strategies by caregivers. Caregiver use of these strategies was associated with positive changes in child language skills.

Sampling strategy for estimating human exposure pathways to consumer chemicals

Directory of Open Access Journals (Sweden)

Eleni Papadopoulou

2016-03-01

Full Text Available Human exposure to consumer chemicals has become a worldwide concern. In this work, a comprehensive sampling strategy is presented, to our knowledge being the first to study all relevant exposure pathways in a single cohort using multiple methods for assessment of exposure from each exposure pathway. The selected groups of chemicals to be studied are consumer chemicals whose production and use are currently in a state of transition and are; per- and polyfluorinated alkyl substances (PFASs, traditional and “emerging” brominated flame retardants (BFRs and EBFRs, organophosphate esters (OPEs and phthalate esters (PEs. Information about human exposure to these contaminants is needed due to existing data gaps on human exposure intakes from multiple exposure pathways and relationships between internal and external exposure. Indoor environment, food and biological samples were collected from 61 participants and their households in the Oslo area (Norway on two consecutive days, during winter 2013-14. Air, dust, hand wipes, and duplicate diet (food and drink samples were collected as indicators of external exposure, and blood, urine, blood spots, hair, nails and saliva as indicators of internal exposure. A food diary, food frequency questionnaire (FFQ and indoor environment questionnaire were also implemented. Approximately 2000 samples were collected in total and participant views on their experiences of this campaign were collected via questionnaire. While 91% of our participants were positive about future participation in a similar project, some tasks were viewed as problematic. Completing the food diary and collection of duplicate food/drink portions were the tasks most frequent reported as “hard”/”very hard”. Nevertheless, a strong positive correlation between the reported total mass of food/drinks in the food record and the total weight of the food/drinks in the collection bottles was observed, being an indication of accurate performance

Strategies for integrating mental health into schools via a multitiered system of support.

Science.gov (United States)

Stephan, Sharon Hoover; Sugai, George; Lever, Nancy; Connors, Elizabeth

2015-04-01

To fully realize the potential of mental health supports in academic settings, it is essential to consider how to effectively integrate the mental health and education systems and their respective resources, staffing, and structures. Historically, school mental health services have not effectively spanned a full continuum of care from mental health promotion to treatment, and several implementation and service challenges have evolved. After an overview of these challenges, best practices and strategies for school and community partners are reviewed to systematically integrate mental health interventions within a school's multitiered system of student support. Copyright © 2015 Elsevier Inc. All rights reserved.

Moon-Mars simulation campaign in volcanic Eifel: Remote science support and sample analysis

Science.gov (United States)

Offringa, Marloes; Foing, Bernard H.; Kamps, Oscar

2016-07-01

Moon-Mars analogue missions using a mock-up lander that is part of the ESA/ILEWG ExoGeoLab project were conducted during Eifel field campaigns in 2009, 2015 and 2016 (Foing et al., 2010). In the last EuroMoonMars2016 campaign the lander was used to conduct reconnaissance experiments and in situ geological scientific analysis of samples, with a payload that mainly consisted of a telescope and a UV-VIS reflectance spectrometer. The aim of the campaign was to exhibit possibilities for the ExoGeoLab lander to perform remotely controlled experiments and test its applicability in the field by simulating the interaction with astronauts. The Eifel region in Germany where the experiments with the ExoGeoLab lander were conducted is a Moon-Mars analogue due to its geological setting and volcanic rock composition. The research conducted by analysis equipment on the lander could function in support of Moon-Mars sample return missions, by providing preliminary insight into characteristics of the analyzed samples. The set-up of the prototype lander was that of a telescope with camera and solar power equipment deployed on the top, the UV-VIS reflectance spectrometer together with computers and a sample webcam were situated in the middle compartment and to the side a sample analysis test bench was attached, attainable by astronauts from outside the lander. An alternative light source that illuminated the samples in case of insufficient daylight was placed on top of the lander and functioned on solar power. The telescope, teleoperated from a nearby stationed pressurized transport vehicle that functioned as a base control center, attained an overview of the sampling area and assisted the astronauts in their initial scouting pursuits. Locations of suitable sampling sites based on these obtained images were communicated to the astronauts, before being acquired during a simulated EVA. Sampled rocks and soils were remotely analyzed by the base control center, while the astronauts

Episodic memory and organizational strategy in free recall in unipolar depression: the role of cognitive support and executive functions.

Science.gov (United States)

Taconnat, Laurence; Baudouin, Alexia; Fay, Severine; Raz, Naftali; Bouazzaoui, Badiaa; El-Hage, Wissam; Isingrini, Michel; Ergis, Anne-Marie

2010-08-01

Executive functioning and memory impairment have been demonstrated in adults with depression. Executive functions and memory are related, mainly when the memory tasks require controlled processes (attentional resource demanding processes)--that is, when a low cognitive support (external aid) is provided. A cross-sectional study was carried out on 45 participants: 21 with depression, and 24 healthy controls matched for age, verbal ability, education level, and anxiety score. Cognitive support was manipulated by providing a categorized word list at encoding, presented either clustered (high cognitive support) or randomized (low cognitive support) to both depressed and healthy adults. The number of words recalled was calculated, and an index of clustering was computed to assess organizational strategies. Participants were also administered cognitive tests (executive functions, cognitive speed, and categorical fluency) to explore the mediators of organizational strategies. Depressed participants had greater difficulty recalling and organizing the words, but the differences between the two groups were reduced for both measures when high cognitive support was provided at encoding. Healthy adults performed better on all cognitive tests. Statistical analyses revealed that in the depressed group, executive functions were the only variable associated with clustering and only when low cognitive support was provided. These findings support the view that the decrement in executive function due to depression may lead to impairment in organization when this mnemonic strategy has to be self-initiated.

An Optimization Model For Strategy Decision Support to Select Kind of CPO’s Ship

Science.gov (United States)

Suaibah Nst, Siti; Nababan, Esther; Mawengkang, Herman

2018-01-01

The selection of marine transport for the distribution of crude palm oil (CPO) is one of strategy that can be considered in reducing cost of transport. The cost of CPO’s transport from one area to CPO’s factory located at the port of destination may affect the level of CPO’s prices and the number of demands. In order to maintain the availability of CPO a strategy is required to minimize the cost of transporting. In this study, the strategy used to select kind of charter ships as barge or chemical tanker. This study aims to determine an optimization model for strategy decision support in selecting kind of CPO’s ship by minimizing costs of transport. The select of ship was done randomly, so that two-stage stochastic programming model was used to select the kind of ship. Model can help decision makers to select either barge or chemical tanker to distribute CPO.

Sampling and Analysis Plan for the 221-U Facility

International Nuclear Information System (INIS)

Rugg, J.E.

1998-02-01

This sampling and analysis plan (SAP) presents the rationale and strategy for the sampling and analysis activities proposed to be conducted to support the evaluation of alternatives for the final disposition of the 221-U Facility. This SAP will describe general sample locations and the minimum number of samples required. It will also identify the specific contaminants of potential concern (COPCs) and the required analysis. This SAP does not define the exact sample locations and equipment to be used in the field due to the nature of unknowns associated with the 221-U Facility

Sampling and Analysis for Tank 241-AW-104 Waste in Support of Evaporator Campaign 2001-1

International Nuclear Information System (INIS)

MCKINNEY, S.G.

2000-01-01

This Tank Sampling and Analysis Plan (TSAP) identifies sample collection, laboratory analysis, quality assurance/quality control (QA/QC), and reporting objectives for the characterization of tank 241-AW-104 waste. Technical bases for these objectives are specified in the 242-A Evaporator Data Quality Objectives (Bowman 2000a and Von Bargen 1998), 242-A Evaporator Quality Assurance Project Plan (Bowman 1998 and Bowman 2000b), Tank 241-AW-104 Sampling Requirements in Support of Evaporator Campaign 2000-1 (Le 2000). Characterization results will be used to support the evaporator campaign currently planned for early fiscal year 2001. No other needs (or issues) requiring data for this tank waste apply to this sampling event

Planning schistosomiasis control: investigation of alternative sampling strategies for Schistosoma mansoni to target mass drug administration of praziquantel in East Africa.

Science.gov (United States)

Sturrock, Hugh J W; Gething, Pete W; Ashton, Ruth A; Kolaczinski, Jan H; Kabatereine, Narcis B; Brooker, Simon

2011-09-01

In schistosomiasis control, there is a need to geographically target treatment to populations at high risk of morbidity. This paper evaluates alternative sampling strategies for surveys of Schistosoma mansoni to target mass drug administration in Kenya and Ethiopia. Two main designs are considered: lot quality assurance sampling (LQAS) of children from all schools; and a geostatistical design that samples a subset of schools and uses semi-variogram analysis and spatial interpolation to predict prevalence in the remaining unsurveyed schools. Computerized simulations are used to investigate the performance of sampling strategies in correctly classifying schools according to treatment needs and their cost-effectiveness in identifying high prevalence schools. LQAS performs better than geostatistical sampling in correctly classifying schools, but at a cost with a higher cost per high prevalence school correctly classified. It is suggested that the optimal surveying strategy for S. mansoni needs to take into account the goals of the control programme and the financial and drug resources available.

Strategies of Female Members of Parliament in Developing Empathy Values to Gain Constituent Support

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Ridhahani

2017-01-01

This qualitative research aims to describe the strategies applied by female parliamentary candidates to develop empathy values to gain constituent support in the legislative general election in 2014. Research subjects comprise 12 female members of parliament from seven regencies/cities in South Kalimantan who were chosen from different…

Graphene-based sample supports for in situ high-resolution TEM electrical investigations

International Nuclear Information System (INIS)

Westenfelder, B; Scholz, F; Meyer, J C; Biskupek, J; Algara-Siller, G; Lechner, L G; Kaiser, U; Kusterer, J; Kohn, E; Krill, C E III

2011-01-01

Specially designed transmission electron microscopy (TEM) sample carriers have been developed to enable atomically resolved studies of the heat-induced evolution of adsorbates on graphene and their influence on electrical conductivity. Here, we present a strategy for graphene-based carrier realization, evaluating its design with respect to fabrication effort and applications potential. We demonstrate that electrical current can lead to very high temperatures in suspended graphene membranes, and we determine that current-induced cleaning of graphene results from Joule heating.

Parental Support, Mental Health, and Alcohol and Marijuana Use in National and High-Risk African-American Adolescent Samples

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Julie Maslowsky

2015-01-01

Full Text Available African-American adolescents experience disproportionate rates of negative consequences of substance use despite using substances at average or below-average rates. Due to underrepresentation of African-American adolescents in etiological literature, risk and protective processes associated with their substance use require further study. This study examines the role of parental support in adolescents’ conduct problems (CPs, depressive symptoms (DSs, and alcohol and marijuana use in a national sample and a high-risk sample of African-American adolescents. In both samples, parental support was inversely related to adolescent CPs, DSs, and alcohol and marijuana use. CPs, but not DSs, partially mediated the relation of parental support to substance use. Results were consistent across the national and high-risk samples, suggesting that the protective effect of parental support applies to African-American adolescents from a range of demographic backgrounds.

Optimal sampling strategy for data mining

International Nuclear Information System (INIS)

Ghaffar, A.; Shahbaz, M.; Mahmood, W.

2013-01-01

Latest technology like Internet, corporate intranets, data warehouses, ERP's, satellites, digital sensors, embedded systems, mobiles networks all are generating such a massive amount of data that it is getting very difficult to analyze and understand all these data, even using data mining tools. Huge datasets are becoming a difficult challenge for classification algorithms. With increasing amounts of data, data mining algorithms are getting slower and analysis is getting less interactive. Sampling can be a solution. Using a fraction of computing resources, Sampling can often provide same level of accuracy. The process of sampling requires much care because there are many factors involved in the determination of correct sample size. The approach proposed in this paper tries to find a solution to this problem. Based on a statistical formula, after setting some parameters, it returns a sample size called s ufficient sample size , which is then selected through probability sampling. Results indicate the usefulness of this technique in coping with the problem of huge datasets. (author)

The efficiency of different search strategies in estimating parsimony jackknife, bootstrap, and Bremer support

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Müller Kai F

2005-10-01

Full Text Available Abstract Background For parsimony analyses, the most common way to estimate confidence is by resampling plans (nonparametric bootstrap, jackknife, and Bremer support (Decay indices. The recent literature reveals that parameter settings that are quite commonly employed are not those that are recommended by theoretical considerations and by previous empirical studies. The optimal search strategy to be applied during resampling was previously addressed solely via standard search strategies available in PAUP*. The question of a compromise between search extensiveness and improved support accuracy for Bremer support received even less attention. A set of experiments was conducted on different datasets to find an empirical cut-off point at which increased search extensiveness does not significantly change Bremer support and jackknife or bootstrap proportions any more. Results For the number of replicates needed for accurate estimates of support in resampling plans, a diagram is provided that helps to address the question whether apparently different support values really differ significantly. It is shown that the use of random addition cycles and parsimony ratchet iterations during bootstrapping does not translate into higher support, nor does any extension of the search extensiveness beyond the rather moderate effort of TBR (tree bisection and reconnection branch swapping plus saving one tree per replicate. Instead, in case of very large matrices, saving more than one shortest tree per iteration and using a strict consensus tree of these yields decreased support compared to saving only one tree. This can be interpreted as a small risk of overestimating support but should be more than compensated by other factors that counteract an enhanced type I error. With regard to Bremer support, a rule of thumb can be derived stating that not much is gained relative to the surplus computational effort when searches are extended beyond 20 ratchet iterations per

Protocol for Microplastics Sampling on the Sea Surface and Sample Analysis

Science.gov (United States)

Kovač Viršek, Manca; Palatinus, Andreja; Koren, Špela; Peterlin, Monika; Horvat, Petra; Kržan, Andrej

2016-01-01

Microplastic pollution in the marine environment is a scientific topic that has received increasing attention over the last decade. The majority of scientific publications address microplastic pollution of the sea surface. The protocol below describes the methodology for sampling, sample preparation, separation and chemical identification of microplastic particles. A manta net fixed on an »A frame« attached to the side of the vessel was used for sampling. Microplastic particles caught in the cod end of the net were separated from samples by visual identification and use of stereomicroscopes. Particles were analyzed for their size using an image analysis program and for their chemical structure using ATR-FTIR and micro FTIR spectroscopy. The described protocol is in line with recommendations for microplastics monitoring published by the Marine Strategy Framework Directive (MSFD) Technical Subgroup on Marine Litter. This written protocol with video guide will support the work of researchers that deal with microplastics monitoring all over the world. PMID:28060297

Using Linked Survey Paradata to Improve Sampling Strategies in the Medical Expenditure Panel Survey

Directory of Open Access Journals (Sweden)

Mirel Lisa B.

2017-06-01

Full Text Available Using paradata from a prior survey that is linked to a new survey can help a survey organization develop more effective sampling strategies. One example of this type of linkage or subsampling is between the National Health Interview Survey (NHIS and the Medical Expenditure Panel Survey (MEPS. MEPS is a nationally representative sample of the U.S. civilian, noninstitutionalized population based on a complex multi-stage sample design. Each year a new sample is drawn as a subsample of households from the prior year’s NHIS. The main objective of this article is to examine how paradata from a prior survey can be used in developing a sampling scheme in a subsequent survey. A framework for optimal allocation of the sample in substrata formed for this purpose is presented and evaluated for the relative effectiveness of alternative substratification schemes. The framework is applied, using real MEPS data, to illustrate how utilizing paradata from the linked survey offers the possibility of making improvements to the sampling scheme for the subsequent survey. The improvements aim to reduce the data collection costs while maintaining or increasing effective responding sample sizes and response rates for a harder to reach population.

Compressed sensing of roller bearing fault based on multiple down-sampling strategy

Science.gov (United States)

Wang, Huaqing; Ke, Yanliang; Luo, Ganggang; Tang, Gang

2016-02-01

Roller bearings are essential components of rotating machinery and are often exposed to complex operating conditions, which can easily lead to their failures. Thus, to ensure normal production and the safety of machine operators, it is essential to detect the failures as soon as possible. However, it is a major challenge to maintain a balance between detection efficiency and big data acquisition given the limitations of sampling theory. To overcome these limitations, we try to preserve the information pertaining to roller bearing failures using a sampling rate far below the Nyquist sampling rate, which can ease the pressure generated by the large-scale data. The big data of a faulty roller bearing’s vibration signals is firstly reduced by a down-sample strategy while preserving the fault features by selecting peaks to represent the data segments in time domain. However, a problem arises in that the fault features may be weaker than before, since the noise may be mistaken for the peaks when the noise is stronger than the vibration signals, which makes the fault features unable to be extracted by commonly-used envelope analysis. Here we employ compressive sensing theory to overcome this problem, which can make a signal enhancement and reduce the sample sizes further. Moreover, it is capable of detecting fault features from a small number of samples based on orthogonal matching pursuit approach, which can overcome the shortcomings of the multiple down-sample algorithm. Experimental results validate the effectiveness of the proposed technique in detecting roller bearing faults.

Compressed sensing of roller bearing fault based on multiple down-sampling strategy

International Nuclear Information System (INIS)

Wang, Huaqing; Ke, Yanliang; Luo, Ganggang; Tang, Gang

2016-01-01

Roller bearings are essential components of rotating machinery and are often exposed to complex operating conditions, which can easily lead to their failures. Thus, to ensure normal production and the safety of machine operators, it is essential to detect the failures as soon as possible. However, it is a major challenge to maintain a balance between detection efficiency and big data acquisition given the limitations of sampling theory. To overcome these limitations, we try to preserve the information pertaining to roller bearing failures using a sampling rate far below the Nyquist sampling rate, which can ease the pressure generated by the large-scale data. The big data of a faulty roller bearing’s vibration signals is firstly reduced by a down-sample strategy while preserving the fault features by selecting peaks to represent the data segments in time domain. However, a problem arises in that the fault features may be weaker than before, since the noise may be mistaken for the peaks when the noise is stronger than the vibration signals, which makes the fault features unable to be extracted by commonly-used envelope analysis. Here we employ compressive sensing theory to overcome this problem, which can make a signal enhancement and reduce the sample sizes further. Moreover, it is capable of detecting fault features from a small number of samples based on orthogonal matching pursuit approach, which can overcome the shortcomings of the multiple down-sample algorithm. Experimental results validate the effectiveness of the proposed technique in detecting roller bearing faults. (paper)

Implementation strategies of internet-based asthma self-management support in usual care. Study protocol for the IMPASSE cluster randomized trial.

Science.gov (United States)

van Gaalen, Johanna L; Bakker, Moira J; van Bodegom-Vos, Leti; Snoeck-Stroband, Jiska B; Assendelft, Willem J J; Kaptein, Ad A; van der Meer, Victor; Taube, Christian; Thoonen, Bart P; Sont, Jacob K

2012-11-21

Internet-based self-management (IBSM) support cost-effectively improves asthma control, asthma related quality of life, number of symptom-free days, and lung function in patients with mild to moderate persistent asthma. The current challenge is to implement IBSM in clinical practice. This study is a three-arm cluster randomized trial with a cluster pre-randomisation design and 12 months follow-up per practice comparing the following three IBSM implementation strategies: minimum strategy (MS): dissemination of the IBSM program; intermediate strategy (IS): MS + start-up support for professionals (i.e., support in selection of the appropriate population and training of professionals); and extended strategy (ES): IS + additional training and ongoing support for professionals. Because the implementation strategies (interventions) are primarily targeted at general practices, randomisation will occur at practice level.In this study, we aim to evaluate 14 primary care practices per strategy in the Leiden-The Hague region, involving 140 patients per arm. Patients aged 18 to 50 years, with a physician diagnosis of asthma, prescription of inhaled corticosteroids, and/or montelukast for ≥3 months in the previous year are eligible to participate. Primary outcome measures are the proportion of referred patients that participate in IBSM, and the proportion of patients that have clinically relevant improvement in the asthma-related quality of life. The secondary effect measures are clinical outcomes (asthma control, lung function, usage of airway treatment, and presence of exacerbations); self-management related outcomes (health education impact, medication adherence, and illness perceptions); and patient utilities. Process measures are the proportion of practices that participate in IBSM and adherence of professionals to implementation strategies. Cost-effective measurements are medical costs and healthcare consumption. Follow-up is six months per patient. This study

Implementation strategies of internet-based asthma self-management support in usual care. Study protocol for the IMPASSE cluster randomized trial

Directory of Open Access Journals (Sweden)

van Gaalen Johanna L

2012-11-01

Full Text Available Abstract Background Internet-based self-management (IBSM support cost-effectively improves asthma control, asthma related quality of life, number of symptom-free days, and lung function in patients with mild to moderate persistent asthma. The current challenge is to implement IBSM in clinical practice. Methods/design This study is a three-arm cluster randomized trial with a cluster pre-randomisation design and 12 months follow-up per practice comparing the following three IBSM implementation strategies: minimum strategy (MS: dissemination of the IBSM program; intermediate strategy (IS: MS + start-up support for professionals (i.e., support in selection of the appropriate population and training of professionals; and extended strategy (ES: IS + additional training and ongoing support for professionals. Because the implementation strategies (interventions are primarily targeted at general practices, randomisation will occur at practice level. In this study, we aim to evaluate 14 primary care practices per strategy in the Leiden-The Hague region, involving 140 patients per arm. Patients aged 18 to 50 years, with a physician diagnosis of asthma, prescription of inhaled corticosteroids, and/or montelukast for ≥3 months in the previous year are eligible to participate. Primary outcome measures are the proportion of referred patients that participate in IBSM, and the proportion of patients that have clinically relevant improvement in the asthma-related quality of life. The secondary effect measures are clinical outcomes (asthma control, lung function, usage of airway treatment, and presence of exacerbations; self-management related outcomes (health education impact, medication adherence, and illness perceptions; and patient utilities. Process measures are the proportion of practices that participate in IBSM and adherence of professionals to implementation strategies. Cost-effective measurements are medical costs and healthcare consumption

Measuring strategies for learning regulation in medical education: scale reliability and dimensionality in a Swedish sample.

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Edelbring, Samuel

2012-08-15

The degree of learners' self-regulated learning and dependence on external regulation influence learning processes in higher education. These regulation strategies are commonly measured by questionnaires developed in other settings than in which they are being used, thereby requiring renewed validation. The aim of this study was to psychometrically evaluate the learning regulation strategy scales from the Inventory of Learning Styles with Swedish medical students (N = 206). The regulation scales were evaluated regarding their reliability, scale dimensionality and interrelations. The primary evaluation focused on dimensionality and was performed with Mokken scale analysis. To assist future scale refinement, additional item analysis, such as item-to-scale correlations, was performed. Scale scores in the Swedish sample displayed good reliability in relation to published results: Cronbach's alpha: 0.82, 0.72, and 0.65 for self-regulation, external regulation and lack of regulation scales respectively. The dimensionalities in scales were adequate for self-regulation and its subscales, whereas external regulation and lack of regulation displayed less unidimensionality. The established theoretical scales were largely replicated in the exploratory analysis. The item analysis identified two items that contributed little to their respective scales. The results indicate that these scales have an adequate capacity for detecting the three theoretically proposed learning regulation strategies in the medical education sample. Further construct validity should be sought by interpreting scale scores in relation to specific learning activities. Using established scales for measuring students' regulation strategies enables a broad empirical base for increasing knowledge on regulation strategies in relation to different disciplinary settings and contributes to theoretical development.

Ground Support Strategies at the Turquoise Ridge Joint Venture, Nevada

Science.gov (United States)

Sandbak, L. A.; Rai, A. R.

2013-05-01

Weak rock masses of high grade Carlin-trend gold mineralization are encountered in the Turquoise Ridge Joint Venture underground mine. The sediments consist of very weak and altered limestone, mudstone, and carbon-rich clays. The rock mass ratings are described as very poor to poor (Bieniawski in Proceedings of the symposium on exploration for rock engineering, Johannesburg, South Africa, pp. 97-106, 1976). The undercut and fill or boxes stoping mining methods are used because of the low dipping ore body geometry, complex geology, and weak rock mass. Design criteria are chosen to keep openings in weak rock as small as possible to prevent unraveling and to minimize supplementary support. Typical ground support for drifting includes the use of bolts, mesh, spiling, and shotcrete. Quality control of cemented rock fill (CRF) through sampling and aggregate sieve testing is necessary to insure high support strength. Specific support may include shotcrete arches with steel ring sets and CRF "arches" as a replacement of weak rock masses around long-term mine openings. Movement monitoring is utilized in problem areas and is needed to quantify and validate computer modeling.

Nursing churn and turnover in Australian hospitals: nurses perceptions and suggestions for supportive strategies.

Science.gov (United States)

Dawson, Angela J; Stasa, Helen; Roche, Michael A; Homer, Caroline S E; Duffield, Christine

2014-04-08

This study aimed to reveal nurses' experiences and perceptions of turnover in Australian hospitals and identify strategies to improve retention, performance and job satisfaction. Nursing turnover is a serious issue that can compromise patient safety, increase health care costs and impact on staff morale. A qualitative design was used to analyze responses from 362 nurses collected from a national survey of nurses from medical and surgical nursing units across 3 Australian States/Territories. A qualitative design was used to analyze responses from 362 nurses collected from a national survey of nurses from medical and surgical nursing units across 3 Australian States/Territories. Key factors affecting nursing turnover were limited career opportunities; poor support; a lack of recognition; and negative staff attitudes. The nursing working environment is characterised by inappropriate skill-mix and inadequate patient-staff ratios; a lack of overseas qualified nurses with appropriate skills; low involvement in decision-making processes; and increased patient demands. These issues impacted upon heavy workloads and stress levels with nurses feeling undervalued and disempowered. Nurses described supportive strategies: improving performance appraisals, responsive preceptorship and flexible employment options. Nursing turnover is influenced by the experiences of nurses. Positive steps can be made towards improving workplace conditions and ensuring nurse retention. Improving performance management and work design are strategies that nurse managers could harness to reduce turnover.

Sensemaking Strategies for Ethical Decision-making.

Science.gov (United States)

Caughron, Jay J; Antes, Alison L; Stenmark, Cheryl K; Thiel, Chaise E; Wang, Xiaoqian; Mumford, Michael D

2011-01-01

The current study uses a sensemaking model and thinking strategies identified in earlier research to examine ethical decision-making. Using a sample of 163 undergraduates, a low fidelity simulation approach is used to study the effects personal involvement (in causing the problem and personal involvement in experiencing the outcomes of the problem) could have on the use of cognitive reasoning strategies that have been shown to promote ethical decision-making. A mediated model is presented which suggests that environmental factors influence reasoning strategies, reasoning strategies influence sensemaking, and sensemaking in turn influences ethical decision-making. Findings were mixed but generally supported the hypothesized model. Interestingly, framing the outcomes of ethically charged situations in terms of more global organizational outcomes rather than personal outcomes was found to promote the use of pro-ethical cognitive reasoning strategies.

Parental Stress, Coping Strategies and Social Support in Families of Children with a Disability

Science.gov (United States)

Cuzzocrea, Francesca; Murdaca, Anna Maria; Costa, Sebastiano; Filippello, Pina; Larcan, Rosalba

2016-01-01

The aim of this research was to compare parental stress, coping strategies and social support perceived in families of children with low functioning autism (n = 8), high functioning autism (n = 10), Down syndrome (n = 12) and parents of typically developing children (n = 20). Specifically, the objective was to investigate which variables (coping…

"What Goes Around Comes Around": Antecedents, Mediators, and Consequences of Controlling vs. Need-Supportive Motivational Strategies Used by Exercise Professionals.

Science.gov (United States)

Silva, Marlene N; Sánchez-Oliva, David; Brunet, Jennifer; Williams, Geoffrey C; Teixeira, Pedro J; Palmeira, Antonio L

2017-10-01

Research into the factors associated with the use of different motivational strategies by exercise professionals is of empirical and practical utility. Grounded in self-determination theory, this study sought to analyze putative antecedents, mediators, and work-related well- and ill-being consequences of two types of motivational strategies reported by exercise professionals. Participants were 366 exercise professionals (193 males; experience = 7.7 ± 5.8 years). Questionnaires assessing psychological need satisfaction frustration, self-determined work motivation, motivational strategies (need-supportive vs. controlling), emotional exhaustion, and personal accomplishment were completed online. Path analysis was used to test the hypothesized model. Model with good fit [χ 2 (5) = 9.174, p> .05; CFI = .984; TLI = .936; RMSEA = .048; SRMR = .022] showed need satisfaction as positively associated with supportive strategies and personal accomplishment (β between .267 and .399) and negatively with emotional exhaustion (β = -.145). Need frustration was negatively associated with work motivation and personal accomplishment (β = -.315; -.176), and positively with controlling strategies and emotional exhaustion (β = .195; .226). Furthermore, supportive strategies and work motivation were positively associated with personal accomplishment (β = .134; .184), whereas controlling strategies were positively associated with emotional exhaustion (β = .178). Findings have theoretical implications, providing evidence of need satisfaction and frustration as being differently associated with work-related motivation, type of strategies used, and work-related emotional outcomes. Practical implications convey the importance of these variables in relation to the standard of motivational strategies provided and their role on work-related well- and ill-being indicators.

In the Aftermath: Attitudes of Anesthesiologists to Supportive Strategies After an Unexpected Intraoperative Patient Death.

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Heard, Gaylene C; Thomas, Rowan D; Sanderson, Penelope M

2016-05-01

Although most anesthesiologists will have 1 catastrophic perioperative event or more during their careers, there has been little research on their attitudes to assistive strategies after the event. There are wide-ranging emotional consequences for anesthesiologists involved in an unexpected intraoperative patient death, particularly if the anesthesiologist made an error. We used a between-groups survey study design to ask whether there are different attitudes to assistive strategies when a hypothetical patient death is caused by a drug error versus not caused by an error. First, we explored attitudes to generalized supportive strategies. Second, we examined our hypothesis that the presence of an error causing the hypothetical patient death would increase the perceived social stigma and self-stigma of help-seeking. Finally, we examined the strategies to assist help-seeking. An anonymous, mailed, self-administered survey was conducted with 1600 consultant anesthesiologists in Australia on the mailing list of the Australian and New Zealand College of Anaesthetists. The participants were randomized into "error" versus "no-error" groups for the hypothetical scenario of patient death due to anaphylaxis. Nonparametric, descriptive, parametric, and inferential tests were used for data analysis. P' is used where P values were corrected for multiple comparisons. There was a usable response rate of 48.9%. When an error had caused the hypothetical patient death, participants were more likely to agree with 4 of the 5 statements about support, including need for time off (P' = 0.003), counseling (P' self-stigma (P = 0.98) or social stigma (P = 0.15) of seeking counseling, whether or not an error had caused the hypothetical patient death. Finally, when an error had caused the patient death, participants were more likely to agree with 2 of the 5 statements about help-seeking, including the need for a formal, hospital-based process that provides information on where to obtain

Development of cost effective fenceline monitoring approaches to support advanced leak detection and repair strategies

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Cost-effective fence line and process monitoring systems to support advanced leak detection and repair (LDAR) strategies can enhance protection of public health, facilitate worker safety, and help companies realize cost savings by reducing lost product. The U.S. EPA Office of Re...

Utilizing Social Network Analysis in Support of Nation Building

Science.gov (United States)

2011-03-01

Commission . . . . . . . . 4-8 IEC Independent Election Commission . . . . . . . . . . . . 4-8 AISA Afghanistan Investment Support Agency...source sample are either in the government or connected to it through the Afghanistan Investment Support Agency ( AISA ). This agency represents an... edition , 1980. 25. Jock Covey, Michael J. Dziedzic, and Leonard R. Hawley. The Quest for Viable Peace: International Intervention and Strategies for

Catch, effort and sampling strategies in the highly variable sardine fisheries around East Java, Indonesia.

NARCIS (Netherlands)

Pet, J.S.; Densen, van W.L.T.; Machiels, M.A.M.; Sukkel, M.; Setyohady, D.; Tumuljadi, A.

1997-01-01

Temporal and spatial patterns in the fishery for Sardinella spp. around East Java, Indonesia, were studied in an attempt to develop an efficient catch and effort sampling strategy for this highly variable fishery. The inter-annual and monthly variation in catch, effort and catch per unit of effort

Sampling strategies for subsampled segmented EPI PRF thermometry in MR guided high intensity focused ultrasound

Science.gov (United States)

Odéen, Henrik; Todd, Nick; Diakite, Mahamadou; Minalga, Emilee; Payne, Allison; Parker, Dennis L.

2014-01-01

Purpose: To investigate k-space subsampling strategies to achieve fast, large field-of-view (FOV) temperature monitoring using segmented echo planar imaging (EPI) proton resonance frequency shift thermometry for MR guided high intensity focused ultrasound (MRgHIFU) applications. Methods: Five different k-space sampling approaches were investigated, varying sample spacing (equally vs nonequally spaced within the echo train), sampling density (variable sampling density in zero, one, and two dimensions), and utilizing sequential or centric sampling. Three of the schemes utilized sequential sampling with the sampling density varied in zero, one, and two dimensions, to investigate sampling the k-space center more frequently. Two of the schemes utilized centric sampling to acquire the k-space center with a longer echo time for improved phase measurements, and vary the sampling density in zero and two dimensions, respectively. Phantom experiments and a theoretical point spread function analysis were performed to investigate their performance. Variable density sampling in zero and two dimensions was also implemented in a non-EPI GRE pulse sequence for comparison. All subsampled data were reconstructed with a previously described temporally constrained reconstruction (TCR) algorithm. Results: The accuracy of each sampling strategy in measuring the temperature rise in the HIFU focal spot was measured in terms of the root-mean-square-error (RMSE) compared to fully sampled “truth.” For the schemes utilizing sequential sampling, the accuracy was found to improve with the dimensionality of the variable density sampling, giving values of 0.65 °C, 0.49 °C, and 0.35 °C for density variation in zero, one, and two dimensions, respectively. The schemes utilizing centric sampling were found to underestimate the temperature rise, with RMSE values of 1.05 °C and 1.31 °C, for variable density sampling in zero and two dimensions, respectively. Similar subsampling schemes

Preparation and analysis of standardized waste samples for Controlled Ecological Life Support Systems (CELSS)

Science.gov (United States)

Carden, J. L.; Browner, R.

1982-01-01

The preparation and analysis of standardized waste samples for controlled ecological life support systems (CELSS) are considered. Analysis of samples from wet oxidation experiments, the development of ion chromatographic techniques utilizing conventional high pressure liquid chromatography (HPLC) equipment, and an investigation of techniques for interfacing an ion chromatograph (IC) with an inductively coupled plasma optical emission spectrometer (ICPOES) are discussed.

Parent-Offspring Conflict over Short-Term Mating Strategies

Directory of Open Access Journals (Sweden)

Spyroulla Georgiou

2011-12-01

Full Text Available Individuals engage in short-term mating strategies that enable them to obtain fitness benefits from casual relationships. These benefits, however, count for less and cost more to their parents. On this basis three hypotheses are tested. First, parents and offspring are likely to disagree over short-term mating strategies, with the former considering these as less acceptable than the latter. Second, parents are more likely to disapprove of the short-term mating strategies of their daughters than of their sons. Finally, mothers and fathers are expected to agree on how much they disagree over the short-term mating strategies of their children. Evidence from a sample of 148 Greek-Cypriot families (140 mothers, 105 fathers, 119 daughters, 77 sons provides support for the first two hypotheses and partial support for the third hypothesis. The implications of these findings for understanding family dynamics are further discussed.

Field screening sampling and analysis strategy and methodology for the 183-H Solar Evaporation Basins: Phase 2, Soils

International Nuclear Information System (INIS)

Antipas, A.; Hopkins, A.M.; Wasemiller, M.A.; McCain, R.G.

1996-01-01

This document provides a sampling/analytical strategy and methodology for Resource Conservation and Recovery Act (RCRA) closure of the 183-H Solar Evaporation Basins within the boundaries and requirements identified in the initial Phase II Sampling and Analysis Plan for RCRA Closure of the 183-H Solar Evaporation Basins

Supporting Students to Develop Concepts Underlying Sampling and to Shuttle Between Contextual and Statistical Spheres

NARCIS (Netherlands)

Bakker, A.; Dierdorp, A.; Maanen, J.A. van; Eijkelhof, H.M.C.

2012-01-01

To stimulate students’ shuttling between contextual and statistical spheres, we based tasks on professional practices. This article focuses on two tasks to support reasoning about sampling by students aged 16-17. The purpose of the tasks was to find out which smaller sample size would have been

Modelling of in-stream nitrogen and phosphorus concentrations using different sampling strategies for calibration data

Science.gov (United States)

Jomaa, Seifeddine; Jiang, Sanyuan; Yang, Xiaoqiang; Rode, Michael

2016-04-01

It is known that a good evaluation and prediction of surface water pollution is mainly limited by the monitoring strategy and the capability of the hydrological water quality model to reproduce the internal processes. To this end, a compromise sampling frequency, which can reflect the dynamical behaviour of leached nutrient fluxes responding to changes in land use, agriculture practices and point sources, and appropriate process-based water quality model are required. The objective of this study was to test the identification of hydrological water quality model parameters (nitrogen and phosphorus) under two different monitoring strategies: (1) regular grab-sampling approach and (2) regular grab-sampling with additional monitoring during the hydrological events using automatic samplers. First, the semi-distributed hydrological water quality HYPE (Hydrological Predictions for the Environment) model was successfully calibrated (1994-1998) for discharge (NSE = 0.86), nitrate-N (lowest NSE for nitrate-N load = 0.69), particulate phosphorus and soluble phosphorus in the Selke catchment (463 km2, central Germany) for the period 1994-1998 using regular grab-sampling approach (biweekly to monthly for nitrogen and phosphorus concentrations). Second, the model was successfully validated during the period 1999-2010 for discharge, nitrate-N, particulate-phosphorus and soluble-phosphorus (lowest NSE for soluble phosphorus load = 0.54). Results, showed that when additional sampling during the events with random grab-sampling approach was used (period 2011-2013), the hydrological model could reproduce only the nitrate-N and soluble phosphorus concentrations reasonably well. However, when additional sampling during the hydrological events was considered, the HYPE model could not represent the measured particulate phosphorus. This reflects the importance of suspended sediment during the hydrological events increasing the concentrations of particulate phosphorus. The HYPE model could

Teachers' Challenges, Strategies, and Support Needs in Schools Affected by Community Violence: A Qualitative Study

Science.gov (United States)

Maring, Elisabeth F.; Koblinsky, Sally A.

2013-01-01

Background: Exposure to community violence compromises teacher effectiveness, student learning, and socioemotional well-being. This study examined the challenges, strategies, and support needs of teachers in urban schools affected by high levels of community violence. Methods: Twenty teachers from 3 urban middle schools with predominantly…

NMR strategies to support medicinal chemistry workflows for primary structure determination.

Science.gov (United States)

Oguadinma, Paul; Bilodeau, Francois; LaPlante, Steven R

2017-01-15

Central to drug discovery is the correct characterization of the primary structures of compounds. In general, medicinal chemists make great synthetic and characterization efforts to deliver the intended compounds. However, there are occasions which incorrect compounds are presented, such as those reported for Bosutinib and TIC10. This may be due to a variety of reasons such as uncontrolled reaction schemes, reliance on limited characterization techniques (LC-MS and/or 1D 1H NMR spectra), or even the lack of availability or knowledge of characterization strategies. Here, we present practical NMR approaches that support medicinal chemist workflows for addressing compound characterization issues and allow for reliable primary structure determinations. These strategies serve to differentiate between regioisomers and geometric isomers, distinguish between N- versus O-alkyl analogues, and identify rotamers and atropisomers. Overall, awareness and application of these available NMR methods (e.g. HMBC/HSQC, ROESY and VT experiments, to name only a few) should help practicing chemists to reveal chemical phenomena and avoid mis-assignment of the primary structures of compounds. Copyright © 2016 Elsevier Ltd. All rights reserved.

The Prediction of Coping Strategies Based on Personality Traits in Irritants Affiliates

Directory of Open Access Journals (Sweden)

Ali Masoud Rostami

2013-07-01

Full Text Available Objective: This study aimed to predict coping strategies based on the characteristics of the stimulants-dependent people. Method: The research method was correlational. The population consisted of all stimulant-dependent individuals (n=402 that consecutively admitted to addiction centers of Tehran over the last year and had a drug dependence diagnosis. By systematic sampling, 201 subjects were selected of this population. The NEO personality inventory (NEO-FFI short form and Lazarus-Folkman’s coping strategies (WCQ-short form questionnaires administered among selected sample. Results: The results showed that there is a positive correlation between the personality dimension of neuroticism and coping strategies of avoidance, disengagement, and a negative one with continence. There is a positive correlation between the personality dimension of extroversion and avoidance, seeking social support and a negative one with (assuming responsibility. Also there is a positive correlation between the personality dimension of compatibility with restraint coping strategies and seeking social support. Conscientiousness personality dimension did not predict any coping strategies in stimulus-dependent patients. Conclusion: Personality traits can predict coping strategies in stimulus-dependent individuals. For the treatment of addicted patients paying attention to evaluation of the patients’ characteristics is suggested.

Current Evidence Supporting Obstetric Fistula Prevention Strategies ...

African Journals Online (AJOL)

Evidences from the articles were linked to prevention strategies retrieved from grey literature. The strategies were classified using an innovative target-focused method. Gaps in the literature show the need for fistula prevention research to aim at systematically measuring incidence and prevalence of the disease, identify the ...

Measuring strategies for learning regulation in medical education: Scale reliability and dimensionality in a Swedish sample

Directory of Open Access Journals (Sweden)

Edelbring Samuel

2012-08-01

Full Text Available Abstract Background The degree of learners’ self-regulated learning and dependence on external regulation influence learning processes in higher education. These regulation strategies are commonly measured by questionnaires developed in other settings than in which they are being used, thereby requiring renewed validation. The aim of this study was to psychometrically evaluate the learning regulation strategy scales from the Inventory of Learning Styles with Swedish medical students (N = 206. Methods The regulation scales were evaluated regarding their reliability, scale dimensionality and interrelations. The primary evaluation focused on dimensionality and was performed with Mokken scale analysis. To assist future scale refinement, additional item analysis, such as item-to-scale correlations, was performed. Results Scale scores in the Swedish sample displayed good reliability in relation to published results: Cronbach’s alpha: 0.82, 0.72, and 0.65 for self-regulation, external regulation and lack of regulation scales respectively. The dimensionalities in scales were adequate for self-regulation and its subscales, whereas external regulation and lack of regulation displayed less unidimensionality. The established theoretical scales were largely replicated in the exploratory analysis. The item analysis identified two items that contributed little to their respective scales. Discussion The results indicate that these scales have an adequate capacity for detecting the three theoretically proposed learning regulation strategies in the medical education sample. Further construct validity should be sought by interpreting scale scores in relation to specific learning activities. Using established scales for measuring students’ regulation strategies enables a broad empirical base for increasing knowledge on regulation strategies in relation to different disciplinary settings and contributes to theoretical development.

Sibship within samples of brown trout ( Salmo trutta ) and implications for supportive breeding

DEFF Research Database (Denmark)

Hansen, Michael Møller; Jensen, L. F.

2005-01-01

We analysed family relationships among brown trout from two small tributary populations that have been suggested as a source of individuals for supportive breeding, using variation at eight microsatellite loci. As a control, we analysed a sample of supposedly unrelated individuals representing...

Development of a decision support model for determining building life-cycle strategies in the Netherlands

NARCIS (Netherlands)

Binnemars, S.; Halman, Johannes I.M.; Durmisevic, Elma; Durmisevic, E.; Pasic, A.

2012-01-01

Over recent years, it has become increasingly apparent that there is a growing need for so-called green buildings with a lower environmental impact over the whole building life-cycle. The construction industry demands strategies that support a drastic change of the way we develop, construct and

Adolescent Girls' Experiences of Discrimination: An Examination of Coping Strategies, Social Support, and Self-Esteem

Science.gov (United States)

Ayres, Melanie M.; Leaper, Campbell

2013-01-01

The research examined (a) girls' responses to personal experiences of gender and/or ethnic/racial discrimination, (b) social support from parents and friends following the discrimination, and (c) the relationship between girls' reported coping strategies to the discrimination and their self-esteem. Participants were 74 adolescent girls…

Reading Strategies to Support Home-to-School Connections Used by Teachers of English Language Learners

Science.gov (United States)

Mendoza, Socorro

2016-01-01

This particularistic qualitative case study design examined reading strategies, approaches, and resources teachers of ELL (English Language Learner) students in kindergarten through third grade use to support reading development and promote the home to school connection regarding literacy proficiency. The purpose of this study was to examine…

Rationale, Implementation and Evaluation of Assistive Strategies for an Active Back-Support Exoskeleton

Directory of Open Access Journals (Sweden)

Stefano Toxiri

2018-05-01

Full Text Available Active exoskeletons are potentially more effective and versatile than passive ones, but designing them poses a number of additional challenges. An important open challenge in the field is associated to the assistive strategy, by which the actuation forces are modulated to the user’s needs during the physical activity. This paper addresses this challenge on an active exoskeleton prototype aimed at reducing compressive low-back loads, associated to risk of musculoskeletal injury during manual material handling (i.e., repeatedly lifting objects. An analysis of the biomechanics of the physical task reveals two key factors that determine low-back loads. For each factor, a suitable control strategy for the exoskeleton is implemented. The first strategy is based on user posture and modulates the assistance to support the wearer’s own upper body. The second one adapts to the mass of the lifted object and is a practical implementation of electromyographic control. A third strategy is devised as a generalized combination of the first two. With these strategies, the proposed exoskeleton can quickly adjust to different task conditions (which makes it versatile compared to using multiple, task-specific, devices as well as to individual preference (which promotes user acceptance. Additionally, the presented implementation is potentially applicable to more powerful exoskeletons, capable of generating larger forces. The different strategies are implemented on the exoskeleton and tested on 11 participants in an experiment reproducing the lifting task. The resulting data highlights that the strategies modulate the assistance as intended by design, i.e., they effectively adjust the commanded assistive torque during operation based on user posture and external mass. The experiment also provides evidence of significant reduction in muscular activity at the lumbar spine (around 30% associated to using the exoskeleton. The reduction is well in line with previous

Does supporting multiple student strategies lead to greater learning and motivation? Investigating a source of complexity in the architecture of intelligent tutoring systems

NARCIS (Netherlands)

Waalkens, Maaike; Aleven, Vincent; Taatgen, Niels

Intelligent tutoring systems (ITS) support students in learning a complex problem-solving skill. One feature that makes an ITS architecturally complex, and hard to build, is support for strategy freedom, that is, the ability to let students pursue multiple solution strategies within a given problem.

Employment Status and Mental Health: Mediating Roles of Social Support and Coping Strategies.

Science.gov (United States)

Perreault, Michel; Touré, El Hadj; Perreault, Nicole; Caron, Jean

2017-09-01

Although it has been established that unemployment and underemployment increase distress and depression, the psychological mechanisms involved are not very clear. This study examines the roles of social support and coping strategies as mediators of the association between employment status and mental health, as well as gender and age differences as moderators. Residents from the epidemiological catchment area of south-west Montreal responded to a randomized household survey for adults in 2009. A follow-up was conducted based on participants' employment status 2 and 4 years later. ANOVAs tests were computed with SPSS to evaluate group differences, and structural equation modeling was performed with AMOS to test mediation effects. At baseline, among participants between 18 and 64 years old (n = 2325), 14.3 % were unemployed/not studying, 14.4 % worked part-time, and 56.5 % worked full-time. Employment status was found to significantly affect depression among those under 45 years old (chi-square = 23.4, p employment with depression, which was fully mediated by social support, less coping with drugs/medication, and less distress. A negative association with full-time employment was also noted with distress, which was partially mediated by increased social support, coping with alcohol, and less coping with drugs/medication. The total indirect effect suggests that full-time employees generally have more resources and do not tend to use avoidance strategies like coping with drugs/medication, resulting in less distress (β = -0.05; p employment, namely full-time employment, in communities.

Supportive monitoring and disease management through the internet: an internet-delivered intervention strategy for recurrent depression.

Science.gov (United States)

Kordy, Hans; Backenstrass, Matthias; Hüsing, Johannes; Wolf, Markus; Aulich, Kai; Bürgy, Martin; Puschner, Bernd; Rummel-Kluge, Christine; Vedder, Helmut

2013-11-01

Major depression is a highly prevalent, disabling disorder associated with loss of quality of life and large economic burden for the society. Depressive disorders often follow a chronic or recurrent course. The risk of relapses increases with each additional episode. The internet-deliverable intervention strategy SUMMIT (SUpportive Monitoring and Disease Management over the InTernet) for patients with recurrent depression has been developed with the main objectives to prolong symptom-free phases and to shorten symptom-loaden phases. This paper describes the study design of a six-sites, three-arm, randomized clinical trial intended to evaluate the efficacy of this novel strategy compared to treatment as usual (TAU). Two hundred thirty six patients who had been treated for their (at least) third depressive episode in one of the six participating psychiatric centers were randomized into one of three groups: 1) TAU plus a twelve-month SUMMIT program participation with personal support or 2) TAU plus a twelve-month SUMMIT program participation without personal support, or 3) TAU alone. Primary outcome of this study is defined as the number of "well weeks" over 24months after index treatment assessed by blind evaluators based on the Longitudinal Interval Follow-Up Evaluation. If efficacious, the low monetary and nonmonetary expenditures of this automated, yet individualized intervention may open new avenues for providing an acceptable, convenient, and affordable long-term disease management strategy to people with a chronic mental condition such as recurrent depression. © 2013.

Sampling and Analysis Plan for the 216-A-29 Ditch

International Nuclear Information System (INIS)

Petersen, S.W.

1998-06-01

This sampling and analysis plan defines procedures to be used for collecting and handling samples to be obtained from the 216-A-29 Ditch, and identifies requirements for field and laboratory measurements. The sampling strategy describes here is derived from a Data Quality Objectives workshop conducted in January 1997 to support sampling to assure worker safety during construction and to assess the validity of a 1988 ditch sampling campaign and the effectiveness of subsequent stabilization. The purpose of the proposed sampling and analysis activities is to characterize soil contamination in the vicinity of a proposed road over the 216-A-29 Ditch

The Impact of Typhoons on the Ocean in the Pacific (ITOP) Field and Data Management Support

Science.gov (United States)

2011-12-16

in October o f 2009 to develop effective sampling strategies for 20 I 0. EOL /Computing Data and Software Facil ity (CDS) supported the !TO P Dry Run...measurement strategies necessitated a dry run experiment in October of 2009 to develop effective sampling strategies for 2010. EOL /Computing Data and...contains products from 21 September through 32 October 2009. The catalog remains accessible at EOL at the above mentioned uri. The products listed by

A Decision Support Tool for Planning the Sampling of Tank 19

International Nuclear Information System (INIS)

Edwards, T.B.

2002-01-01

The Statistical Consulting Section (SCS) of the Savannah River Technology Center (SRTC) was asked to develop a decision support system (DSS) to aid in the planning of the process to characterize the heel of Tank 19. This characterization is to be based on samples of the tank heel, and the DSS is to be used to help determine the number of samples that might be needed to provide a meaningful characterization based upon assumptions for relevant variations and volumes. The objective of this report is to describe the framework used to develop the DSS and to document its calculations. The DSS was developed as a Microsoft Excel spreadsheet. Detailed input and output for two test cases are provided in the appendix as part of the documentation of this spreadsheet

Quality management as a strategy to support collection development in legal libraries

Directory of Open Access Journals (Sweden)

Ana Cláudia Carvalho de Miranda

2016-05-01

Full Text Available Libraries are seen as non-profit organizations, their main objective is to offer quality in information mediation, in order to meet the user´s specific information needs. Thus, as organizations, libraries need to apply management strategies that aim to guarantee its effectiveness and efficiency to ensure its survival. Amongst some strategies is quality management. This article aims to propose a debate regarding quality management applied to Collections Development in Legal Libraries. In order to attend these objectives, literature review was realized considering the areas of Quality, Collection Development. In this process, the research identifies the main characteristics applied to Law Libraries, characterizes Legal information as well as points out the main challenges in this area and possible solutions. Based on the reflections given, it can be confirmed that the role of the legal library is to disseminate legal information in the institutions to which they belong to, support legal decisions, work with law in its raw state so it can be interpreted, aiming to reach certain standards contributing to peace in society. It is concluded that for this process to be fulfilled it is necessary the effective implementation of strategies for ensuring the quality of the provided services.

Practical experiences with an extended screening strategy for genetically modified organisms (GMOs) in real-life samples.

Science.gov (United States)

Scholtens, Ingrid; Laurensse, Emile; Molenaar, Bonnie; Zaaijer, Stephanie; Gaballo, Heidi; Boleij, Peter; Bak, Arno; Kok, Esther

2013-09-25

Nowadays most animal feed products imported into Europe have a GMO (genetically modified organism) label. This means that they contain European Union (EU)-authorized GMOs. For enforcement of these labeling requirements, it is necessary, with the rising number of EU-authorized GMOs, to perform an increasing number of analyses. In addition to this, it is necessary to test products for the potential presence of EU-unauthorized GMOs. Analysis for EU-authorized and -unauthorized GMOs in animal feed has thus become laborious and expensive. Initial screening steps may reduce the number of GMO identification methods that need to be applied, but with the increasing diversity also screening with GMO elements has become more complex. For the present study, the application of an informative detailed 24-element screening and subsequent identification strategy was applied in 50 animal feed samples. Almost all feed samples were labeled as containing GMO-derived materials. The main goal of the study was therefore to investigate if a detailed screening strategy would reduce the number of subsequent identification analyses. An additional goal was to test the samples in this way for the potential presence of EU-unauthorized GMOs. Finally, to test the robustness of the approach, eight of the samples were tested in a concise interlaboratory study. No significant differences were found between the results of the two laboratories.

Digital Content Strategies

OpenAIRE

Halbheer, Daniel; Stahl, Florian; Koenigsberg, Oded; Lehmann, Donald R

2013-01-01

This paper studies content strategies for online publishers of digital information goods. It examines sampling strategies and compares their performance to paid content and free content strategies. A sampling strategy, where some of the content is offered for free and consumers are charged for access to the rest, is known as a "metered model" in the newspaper industry. We analyze optimal decisions concerning the size of the sample and the price of the paid content when sampling serves the dua...

Towards an optimal sampling strategy for assessing genetic variation within and among white clover (Trifolium repens L. cultivars using AFLP

Directory of Open Access Journals (Sweden)

Khosro Mehdi Khanlou

2011-01-01

Full Text Available Cost reduction in plant breeding and conservation programs depends largely on correctly defining the minimal sample size required for the trustworthy assessment of intra- and inter-cultivar genetic variation. White clover, an important pasture legume, was chosen for studying this aspect. In clonal plants, such as the aforementioned, an appropriate sampling scheme eliminates the redundant analysis of identical genotypes. The aim was to define an optimal sampling strategy, i.e., the minimum sample size and appropriate sampling scheme for white clover cultivars, by using AFLP data (283 loci from three popular types. A grid-based sampling scheme, with an interplant distance of at least 40 cm, was sufficient to avoid any excess in replicates. Simulations revealed that the number of samples substantially influenced genetic diversity parameters. When using less than 15 per cultivar, the expected heterozygosity (He and Shannon diversity index (I were greatly underestimated, whereas with 20, more than 95% of total intra-cultivar genetic variation was covered. Based on AMOVA, a 20-cultivar sample was apparently sufficient to accurately quantify individual genetic structuring. The recommended sampling strategy facilitates the efficient characterization of diversity in white clover, for both conservation and exploitation.

Strategy-aligned fuzzy approach for market segment evaluation and selection: a modular decision support system by dynamic network process (DNP)

Science.gov (United States)

Mohammadi Nasrabadi, Ali; Hosseinpour, Mohammad Hossein; Ebrahimnejad, Sadoullah

2013-05-01

In competitive markets, market segmentation is a critical point of business, and it can be used as a generic strategy. In each segment, strategies lead companies to their targets; thus, segment selection and the application of the appropriate strategies over time are very important to achieve successful business. This paper aims to model a strategy-aligned fuzzy approach to market segment evaluation and selection. A modular decision support system (DSS) is developed to select an optimum segment with its appropriate strategies. The suggested DSS has two main modules. The first one is SPACE matrix which indicates the risk of each segment. Also, it determines the long-term strategies. The second module finds the most preferred segment-strategies over time. Dynamic network process is applied to prioritize segment-strategies according to five competitive force factors. There is vagueness in pairwise comparisons, and this vagueness has been modeled using fuzzy concepts. To clarify, an example is illustrated by a case study in Iran's coffee market. The results show that success possibility of segments could be different, and choosing the best ones could help companies to be sure in developing their business. Moreover, changing the priority of strategies over time indicates the importance of long-term planning. This fact has been supported by a case study on strategic priority difference in short- and long-term consideration.

Serum sample containing endogenous antibodies interfering with multiple hormone immunoassays. Laboratory strategies to detect interference

Directory of Open Access Journals (Sweden)

Elena García-González

2016-04-01

Full Text Available Objectives: Endogenous antibodies (EA may interfere with immunoassays, causing erroneous results for hormone analyses. As (in most cases this interference arises from the assay format and most immunoassays, even from different manufacturers, are constructed in a similar way, it is possible for a single type of EA to interfere with different immunoassays. Here we describe the case of a patient whose serum sample contains EA that interfere several hormones tests. We also discuss the strategies deployed to detect interference. Subjects and methods: Over a period of four years, a 30-year-old man was subjected to a plethora of laboratory and imaging diagnostic procedures as a consequence of elevated hormone results, mainly of pituitary origin, which did not correlate with the overall clinical picture. Results: Once analytical interference was suspected, the best laboratory approaches to investigate it were sample reanalysis on an alternative platform and sample incubation with antibody blocking tubes. Construction of an in-house ‘nonsense’ sandwich assay was also a valuable strategy to confirm interference. In contrast, serial sample dilutions were of no value in our case, while polyethylene glycol (PEG precipitation gave inconclusive results, probably due to the use of inappropriate PEG concentrations for several of the tests assayed. Conclusions: Clinicians and laboratorians must be aware of the drawbacks of immunometric assays, and alert to the possibility of EA interference when results do not fit the clinical pattern. Keywords: Endogenous antibodies, Immunoassay, Interference, Pituitary hormones, Case report

[Identification of Systemic Contaminations with Legionella Spec. in Drinking Water Plumbing Systems: Sampling Strategies and Corresponding Parameters].

Science.gov (United States)

Völker, S; Schreiber, C; Müller, H; Zacharias, N; Kistemann, T

2017-05-01

After the amendment of the Drinking Water Ordinance in 2011, the requirements for the hygienic-microbiological monitoring of drinking water installations have increased significantly. In the BMBF-funded project "Biofilm Management" (2010-2014), we examined the extent to which established sampling strategies in practice can uncover drinking water plumbing systems systemically colonized with Legionella. Moreover, we investigated additional parameters that might be suitable for detecting systemic contaminations. We subjected the drinking water plumbing systems of 8 buildings with known microbial contamination (Legionella) to an intensive hygienic-microbiological sampling with high spatial and temporal resolution. A total of 626 drinking hot water samples were analyzed with classical culture-based methods. In addition, comprehensive hygienic observations were conducted in each building and qualitative interviews with operators and users were applied. Collected tap-specific parameters were quantitatively analyzed by means of sensitivity and accuracy calculations. The systemic presence of Legionella in drinking water plumbing systems has a high spatial and temporal variability. Established sampling strategies were only partially suitable to detect long-term Legionella contaminations in practice. In particular, the sampling of hot water at the calorifier and circulation re-entrance showed little significance in terms of contamination events. To detect the systemic presence of Legionella,the parameters stagnation (qualitatively assessed) and temperature (compliance with the 5K-rule) showed better results. © Georg Thieme Verlag KG Stuttgart · New York.

Sampling and Analysis Plan for Tank 241-AP-108 Waste in Support of Evaporator Campaign 2000-1

International Nuclear Information System (INIS)

RASMUSSEN, J.H.

2000-01-01

This Tank Sampling and Analysis Plan (TSAP) identifies sample collection, laboratory analysis, quality assurance/quality control (QA/QC), and reporting objectives for the characterization of tank 241-AP-108 waste. Technical bases for these objectives are specified in the 242-A Evaporator Data Quality Objectives (Bowman 2000 and Von Bargen 1998) and 108-AP Tank Sampling Requirements in Support of Evaporator Campaign 2000-1 (Le 2000). Evaporator campaign 2000-1 will process waste from tank 241-AP-108 in addition to that from tank 241-AP-107. Characterization results will be used to support the evaporator campaign currently planned for early fiscal year 2000. No other needs (or issues) requiring data for this tank waste apply to this sampling event

A sampling strategy to establish existing plant configuration baselines

International Nuclear Information System (INIS)

Buchanan, L.P.

1995-01-01

The Department of Energy's Gaseous Diffusion Plants (DOEGDP) are undergoing a Safety Analysis Update Program. As part of this program, critical existing structures are being reevaluated for Natural Phenomena Hazards (NPH) based on the recommendations of UCRL-15910. The Department of Energy has specified that current plant configurations be used in the performance of these reevaluations. This paper presents the process and results of a walkdown program implemented at DOEGDP to establish the current configuration baseline for these existing critical structures for use in subsequent NPH evaluations. These structures are classified as moderate hazard facilities and were constructed in the early 1950's. The process involved a statistical sampling strategy to determine the validity of critical design information as represented on the original design drawings such as member sizes, orientation, connection details and anchorage. A floor load inventory of the dead load of the equipment, both permanently attached and spare, was also performed as well as a walkthrough inspection of the overall structure to identify any other significant anomalies

Strategies and Decision Support Systems for Integrating Variable Energy Resources in Control Centers for Reliable Grid Operations

Energy Technology Data Exchange (ETDEWEB)

Jones, Lawrence E. [Alstom Grid Inc., Washington, DC (United States)

2011-11-01

This report provides findings from the field regarding the best ways in which to guide operational strategies, business processes and control room tools to support the integration of renewable energy into electrical grids.

TXRF versus conventional EDXRF using 150 nm AP1 sample support films

International Nuclear Information System (INIS)

Wobrauschek, P.; Buzanich, G.; Marosi, N.

2000-01-01

Total reflection x-ray fluorescence analysis (TXRF ) is a powerful analytical tool for trace element analysis in the ng/g concentration or pg absolute region for medium Z elements using commercial or own designed TXRF equipment. One of the goals of TXRF is the extreme small penetration depth of the primary radiation into the reflector - substrate of 3-4 run if an incidence angle of about 1 mrad is adjusted. Among others, this effect results in a drastically reduced background in the measured spectra. This is caused by the reduction of elastic and inelastic scattered primary radiation from the substrate. Since there are now thin film supports commercially available having a thickness of 150 nm it is interesting to compare experimental results using TXRF and sample support films in 45 o incident beam and 45 o fluorescence emission geometry. As this film is only about 50 times more in thickness than the penetration depth in a quartz reflector, tests were performed to compare the analytical results and detection limits achievable from the same samples analyzed in total reflection geometry on a quartz reflector and conventional EDRXS geometry on the AP1 film with a dimple in the center for easy placing of the droplet. A volume of 3-5 μl of a liquid sample were used in both cases, pipetted and vacuum dried to prepare the sample. A high power 3 kW Mo-anode X-ray tube was used, for TXRF the line focus and for the conventional geometry the point focus was chosen. As additional results measurements from the TRACOR TN 5000 spectrometer will be presented using an air cooled low power tube with Rh - anode in a compact commercially available unit. A comparison of the results will be given in terms of sensitivity and detection limits, and future aspects for improvements and applications will be discussed. (author)

Technical support organization of national regulators: Challenges and strategy

International Nuclear Information System (INIS)

Mallick, S.A.; Maqbul, N.; Kanwal, S.; Hashmi, J.A.

2007-01-01

technical support organization called the 'Centre for Nuclear Safety' within PNRA to meet the future regulatory challenges. This paper discusses the objectives and organization of Centre for Nuclear Safety and the challenges that the centre is facing as the strategy being devised to meet those challenges. The paper includes a brief description of co-operation under an IAEA TC project titled 'Further Improvement of Nuclear Regulatory Infrastructure in Pakistan-(PAK/9/28)' which is an example of international co-operation in the establishment of technical support organization to enhance the regulatory effectiveness of the national regulator in Pakistan. (author)

Allocation Anatomy: How District Policies That Deploy Resources Can Support (or Undermine) District Reform Strategies

Science.gov (United States)

Roza, Marguerite

2008-01-01

The goal of this paper is to explore the effects of micro-budgeting decisions and show how they might support or hamper district reform strategies. The study draws on public and private sector resource allocation literature to identify key elements of resource allocation decisions. These elements are used to highlight different allocation…

Flora sampling in the vicinity of gamma greenhouse: As a flora sampling model for supporting the national nuclear power program (NPP)

International Nuclear Information System (INIS)

Affrida Abu Hassan; Zaiton Ahmad; Ros Anita Ahmad Ramli; Shakinah Salleh; Norazlina Noordin; Salmah Moosa; Sakinah Ariffin; Salahbiah Abdul Majid; Nur Humaira Lau Abdullah; Mohd Zaidan Kandar; Abdul Rahim Harun

2012-01-01

Gamma Green House was used as a model to study radiation effects on flora and ecosystems in supporting the National Nuclear Power Programme (NPP). A task force was formed in BAB which consists of 3 main groups of flora, fauna and microorganisms. For the flora group, two sampling expeditions have been carried out on July 7, 2011 and March 2, 2012 with the assistant of experts from University Putra Malaysia. From these expeditions, a preliminary data on the types and distribution of plants in selected quadrants close to the Gamma Greenhouse has been successfully observed and the collected plant samples have been preserved as part of the herbarium collection. This paper will describe on the sampling activities and sample preservation. Knowledge gained from this study will be very useful as model for flora distribution baseline data at plant site(author)

Reading Strategies Used by Iranian EFL Learners While Reading Academic Texts

Directory of Open Access Journals (Sweden)

Vida Yousefian

2015-11-01

Full Text Available The major aim of this study was to explore the nature and frequency of the reading strategies used by the EFL learners while reading academic texts. Normally, students tend to read all the information provided in reading materials. This study explores whether learners use reading strategies to assist them in reading comprehension. There was a sample of 45 English language (EFL learners from Islamic Azad University, Falavarjan Branch. The instrument utilized in this study was a survey questionnaire with 30 items including 13 global reading strategies, 8 problem solving strategies and 9 support reading strategies. The survey was going to signify how much EFL learners use each of these strategies while reading academic texts. The findings indicated that the participants used global reading strategies more (44.5% than problem solving strategies (29.0% and support reading strategies (26.5%. The results of the present study will let the instructors improve the reading strategies which are not used by EFL learners frequently. It also helps learners to promote the ability of using reading strategies and utilize the strategies in an appropriate and effective way.

Evaluation of the Environmental Supports Scale with a Community Sample of Adolescents.

Science.gov (United States)

Risco, Cristina M; Collado, Anahi D; Reynolds, Elizabeth K; Lejuez, Carl W; MacPherson, Laura

2016-05-01

Environmental sources of psychosocial support have been found to modulate or protect against the development of psychopathology and risk behavior among adolescents. Capturing sources of environmental support across multiple developmental contexts requires the availability of well-validated, concise assessments-of which there are few in the existing literature. In order to address this need, the current study explored the factor structure, concurrent and convergent validity of the Environmental Supports Scale (ESS; Genetic, Social, and General Psychology Monographs, 117; 395-417, 1991) with a community sample of adolescents. An unconstrained exploratory factor analysis revealed a separate factor for home, school, and neighborhood settings. Internal consistency and test-retest reliability were evaluated for each factor. Concurrent and predictive validity analyses revealed that the ESS was associated in the expected directions across a range of constructs relevant to adolescent development including internalizing symptoms, well-being, external influences, and engagement in risk behavior. Convergent validity for the neighborhood context was established with an assessment of neighborhood environmental adversity. A brief assessment of perceived environmental support across key developmental contexts provides an important tool for research on resilience processes during adolescence and may help illuminate key protective factors and inform intervention and prevention efforts.

Effects of cooperative learning strategy on undergraduate kinesiology students' learning styles.

Science.gov (United States)

Meeuwsen, Harry J; King, George A; Pederson, Rockie

2005-10-01

A growing body of research supports cooperative learning as an effective teaching strategy. A specific cooperative learning strategy, Team-based Learning, was applied to a convenience sample of four undergraduate sophomore-level motor behavior courses over four semesters from Fall 2002 to Spring 2004 to examine whether this strategy would affect students' learning styles. The data from the Grasha-Reichmann Student Learning Style Scales indicated that this teaching strategy was associated with a significant decrease in the negative Avoidant and Dependent learning styles and an improvement in the positive Participant learning style.

Strategies for International Cooperation in Support of Energy Development in Pacific Island Nations

Energy Technology Data Exchange (ETDEWEB)

Miller, M.; Voss, P.; Warren, A.; Baring-Gould, I.; Conrad, M.

2012-05-01

The U.S. Department of Energy's National Renewable Energy Laboratory (NREL) has been partnering with island communities around the world to address the technical, policy, social, and economic hurdles to deploying energy efficiency and renewable energy technologies (RETs) on small, islanded systems. The lessons learned from these partnerships are briefly summarized in this document with the goal of supporting the International Renewable Energy Agency (IRENA) in the development of specific near-term and longer-term strategies for island RET deployment.

Rats track odour trails accurately using a multi-layered strategy with near-optimal sampling.

Science.gov (United States)

Khan, Adil Ghani; Sarangi, Manaswini; Bhalla, Upinder Singh

2012-02-28

Tracking odour trails is a crucial behaviour for many animals, often leading to food, mates or away from danger. It is an excellent example of active sampling, where the animal itself controls how to sense the environment. Here we show that rats can track odour trails accurately with near-optimal sampling. We trained rats to follow odour trails drawn on paper spooled through a treadmill. By recording local field potentials (LFPs) from the olfactory bulb, and sniffing rates, we find that sniffing but not LFPs differ between tracking and non-tracking conditions. Rats can track odours within ~1 cm, and this accuracy is degraded when one nostril is closed. Moreover, they show path prediction on encountering a fork, wide 'casting' sweeps on encountering a gap and detection of reappearance of the trail in 1-2 sniffs. We suggest that rats use a multi-layered strategy, and achieve efficient sampling and high accuracy in this complex task.

Coping strategy and social support modify the association between perceived stress and C-reactive protein: a longitudinal study of healthy men and women.

Science.gov (United States)

Shimanoe, Chisato; Hara, Megumi; Nishida, Yuichiro; Nanri, Hinako; Otsuka, Yasuko; Horita, Mikako; Yasukata, Jun; Miyoshi, Nobuyuki; Yamada, Yosuke; Higaki, Yasuki; Tanaka, Keitaro

2018-05-01

Inconsistent associations have been reported between perceived stress and C-reactive protein (CRP), a marker of systemic inflammation. We previously observed a male-specific inverse relationship between perceived stress and CRP in a cross-sectional study. In the present study, we examined the longitudinal association between changes in perceived stress and CRP, and further analyzed whether changes in coping strategies and social support modify this association. This study included 8454 participants in both a baseline survey and a follow-up survey 5 years later. Psychosocial measures (i.e. perceived stress, coping strategies, and social support) and CRP concentrations were measured by identical means in both surveys. Consistent with our previous findings, increased perceived stress was significantly associated with lower CRP in men (p trend  = .037), but not in women. Increased "emotional expression," a coping strategy, was also associated with lower CRP in women (p trend  = .024). Furthermore, interactions between perceived stress and a coping strategy (positive reappraisal) or social support on CRP were found in men (p interaction  = .007 and .038, respectively); the above inverse association between stress and CRP was not detected for participants with diminished positive reappraisal or social support. In conclusion, increases in perceived stress during a 5-year period were associated with decreases in CRP among healthy men, and the observed association was possibly modified by coping strategy or social support.

Comparative Multi-Criteria Assessment of Climate Policies and Sustainable Development Strategies in Cameroon: Towards a GIS Decision-Support Tool for the Design of an Optimal REDD+ Strategy

Directory of Open Access Journals (Sweden)

Anderson Gwanyebit Kehbila

2014-09-01

Full Text Available Cameroon is committed to reducing emissions from deforestation and forest degradation plus conservation, sustainable management of forests and enhancement of carbon stocks (REDD+. To achieve this goal, the government has introduced a series of policy reforms and formulated a number of key strategic planning documents to advance the REDD+ readiness process in Cameroon. This paper assesses the extent to which major cross-sectoral policies support or impede the development and implementation of an optimal REDD+ strategy in Cameroon from a comparative multi-criteria perspective. Study results reveal that a majority of the policy instruments reviewed appeared to be less prescriptive in terms of any tangible REDD+ strategy, as they do not have provisions for tangible measures to reduce deforestation and forest degradation. Given the lack of adequate flexibility, prompt review and responsiveness of these cross-sectoral policies to adapt themselves to new realities and respond to a changing environment, this paper introduces a GIS-REDD+ decision support system (GIS-REDD+DSS that is necessary to support the adaptive element of an adaptive REDD+ strategy in Cameroon. The GIS-REDD+DSS, an electronic REDD+agri intermediary hub, serves the following purpose: (1 host a database of locally-relevant climate information, improved input technologies, best practices as well as land use and forest cover geo-spatial maps; (2 host a virtual economic tool that performs economic valuations (costs and benefits and financial analysis of REDD+agri projects to aid investment decision-making; and (3 host an electronic marketplace to mediate any-to-any transactions among REDD+agri project developers, service providers, input suppliers, private and institutional investors and buyers (wholesalers and retailers, thereby creating value in two ways: aggregation and matching. This decision support tool, we argue, is a fundamental prerequisite for “policy and REDD+ safeguard

Coping strategies: gender differences and development throughout life span.

Science.gov (United States)

Meléndez, Juan Carlos; Mayordomo, Teresa; Sancho, Patricia; Tomás, José Manuel

2012-11-01

Development during life-span implies to cope with stressful events, and this coping may be done with several strategies. It could be useful to know if these coping strategies differ as a consequence of personal characteristics. This work uses the Coping with Stress Questionnaire with this aim using a sample of 400 participants. Specifically, the effects of gender and age group (young people, middle age and elderly), as well as its interaction on coping strategies is studied. With regard to age, on one hand, it is hypothesised a decrement in the use of coping strategies centred in problem solving and social support seeking as age increases. On the other hand, the use of emotional coping is hypothesised to increase with age. With respect to gender, it is hypothesised a larger use of emotional coping and social support seeking within women, and a larger use of problem solving within men. A MANOVA found significant effects for the two main effects (gender and age) as well as several interactions. Separate ANOVAs allowed us to test for potential differences in each of the coping strategies measured in the CAE. These results partially supported the hypotheses. Results are discussed in relation to scientific literature on coping, age and gender.

Spatiotemporally Representative and Cost-Efficient Sampling Design for Validation Activities in Wanglang Experimental Site

Directory of Open Access Journals (Sweden)

Gaofei Yin

2017-11-01

Full Text Available Spatiotemporally representative Elementary Sampling Units (ESUs are required for capturing the temporal variations in surface spatial heterogeneity through field measurements. Since inaccessibility often coexists with heterogeneity, a cost-efficient sampling design is mandatory. We proposed a sampling strategy to generate spatiotemporally representative and cost-efficient ESUs based on the conditioned Latin hypercube sampling scheme. The proposed strategy was constrained by multi-temporal Normalized Difference Vegetation Index (NDVI imagery, and the ESUs were limited within a sampling feasible region established based on accessibility criteria. A novel criterion based on the Overlapping Area (OA between the NDVI frequency distribution histogram from the sampled ESUs and that from the entire study area was used to assess the sampling efficiency. A case study in Wanglang National Nature Reserve in China showed that the proposed strategy improves the spatiotemporally representativeness of sampling (mean annual OA = 74.7% compared to the single-temporally constrained (OA = 68.7% and the random sampling (OA = 63.1% strategies. The introduction of the feasible region constraint significantly reduces in-situ labour-intensive characterization necessities at expenses of about 9% loss in the spatiotemporal representativeness of the sampling. Our study will support the validation activities in Wanglang experimental site providing a benchmark for locating the nodes of automatic observation systems (e.g., LAINet which need a spatially distributed and temporally fixed sampling design.

Draft evaluation of the frequency for gas sampling for the high burnup confirmatory data project

Energy Technology Data Exchange (ETDEWEB)

Stockman, Christine T. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Alsaed, Halim A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Bryan, Charles R. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-03-26

This report fulfills the M3 milestone M3FT-15SN0802041, “Draft Evaluation of the Frequency for Gas Sampling for the High Burn-up Storage Demonstration Project” under Work Package FT-15SN080204, “ST Field Demonstration Support – SNL”. This report provides a technically based gas sampling frequency strategy for the High Burnup (HBU) Confirmatory Data Project. The evaluation of: 1) the types and magnitudes of gases that could be present in the project cask and, 2) the degradation mechanisms that could change gas compositions culminates in an adaptive gas sampling frequency strategy. This adaptive strategy is compared against the sampling frequency that has been developed based on operational considerations. Gas sampling will provide information on the presence of residual water (and byproducts associated with its reactions and decomposition) and breach of cladding, which could inform the decision of when to open the project cask.

The analytical calibration in (bio)imaging/mapping of the metallic elements in biological samples--definitions, nomenclature and strategies: state of the art.

Science.gov (United States)

Jurowski, Kamil; Buszewski, Bogusław; Piekoszewski, Wojciech

2015-01-01

Nowadays, studies related to the distribution of metallic elements in biological samples are one of the most important issues. There are many articles dedicated to specific analytical atomic spectrometry techniques used for mapping/(bio)imaging the metallic elements in various kinds of biological samples. However, in such literature, there is a lack of articles dedicated to reviewing calibration strategies, and their problems, nomenclature, definitions, ways and methods used to obtain quantitative distribution maps. The aim of this article was to characterize the analytical calibration in the (bio)imaging/mapping of the metallic elements in biological samples including (1) nomenclature; (2) definitions, and (3) selected and sophisticated, examples of calibration strategies with analytical calibration procedures applied in the different analytical methods currently used to study an element's distribution in biological samples/materials such as LA ICP-MS, SIMS, EDS, XRF and others. The main emphasis was placed on the procedures and methodology of the analytical calibration strategy. Additionally, the aim of this work is to systematize the nomenclature for the calibration terms: analytical calibration, analytical calibration method, analytical calibration procedure and analytical calibration strategy. The authors also want to popularize the division of calibration methods that are different than those hitherto used. This article is the first work in literature that refers to and emphasizes many different and complex aspects of analytical calibration problems in studies related to (bio)imaging/mapping metallic elements in different kinds of biological samples. Copyright © 2014 Elsevier B.V. All rights reserved.

Effects of Issue-Image Strategies, Attack and Support Appeals, Music, and Visual Content in Political Commercials.

Science.gov (United States)

Thorson, Esther; And Others

1991-01-01

This study analyzed four characteristics of political commercials to determine their impact on television viewers' reactions: (1) issue versus image strategies; (2) attack versus support appeals; (3) presence and absence of music; and (4) visual content, either with families or in professional campaign settings. Memory measures and attitudes are…

Literacy-Related Play Activities and Preschool Staffs' Strategies to Support Children's Concept Development

Science.gov (United States)

Norling, Martina; Lillvist, Anne

2016-01-01

This study investigates language-promoting strategies and support of concept development displayed by preschool staffs' when interacting with preschool children in literacy-related play activities. The data analysed consisted of 39 minutes of video, selected systematically from a total of 11 hours of video material from six Swedish preschool…

Major Differences in Advanced Life Support Training Strategies Among Danish Hospitals - A Nationwide Study

DEFF Research Database (Denmark)

Glerup Lauridsen, Kasper; Mygind-Klausen, Troels; Stærk, Mathilde

2017-01-01

Introduction: Advanced life support (ALS) training may increase survival from in-hospital cardiac arrest. Efficient ALS training includes practice of both technical and non-technical skills in a realistic setting with frequent retraining to avoid decay in ALS skills. ALS training strategies among...... hospitals are currently unknown. This study aimed to investigate ALS training strategies in Danish hospitals.Methods: We included all public, somatic hospitals in Denmark with a cardiac arrest team (n=46). Online questionnaires were distributed to resuscitation officers in each hospital. Questionnaires...... inquired information on: A) Course duration and retraining interval, B) Training methods and setting, C) Scenario training and practicing non-technical skills.Results: In total, 44 hospitals replied (response rate: 96%). ALS training was conducted in 43 hospitals (98%). Median (range) ALS course duration...

Interim Control Strategy for the Test Area North/Technical Support Facility Sewage Treatment Facility Disposal Pond - Two-year Update

International Nuclear Information System (INIS)

L. V. Street

2007-01-01

The Idaho Cleanup Project has prepared this interim control strategy for the U.S. Department of Energy Idaho Operations Office pursuant to DOE Order 5400.5, Chapter 11.3e (1) to support continued discharges to the Test Area North/Technical Support Facility Sewage Treatment Facility Disposal Pond. In compliance with DOE Order 5400.5, a 2-year review of the Interim Control Strategy document has been completed. This submittal documents the required review of the April 2005 Interim Control Strategy. The Idaho Cleanup Project's recommendation is unchanged from the original recommendation. The Interim Control Strategy evaluates three alternatives: (1) re-route the discharge outlet to an uncontaminated area of the TSF-07; (2) construct a new discharge pond; or (3) no action based on justification for continued use. Evaluation of Alternatives 1 and 2 are based on the estimated cost and implementation timeframe weighed against either alternative's minimal increase in protection of workers, the public, and the environment. Evaluation of Alternative 3, continued use of the TSF-07 Disposal Pond under current effluent controls, is based on an analysis of four points: - Record of Decision controls will protect workers and the public - Risk of increased contamination is low - Discharge water will be eliminated in the foreseeable future - Risk of contamination spread is acceptable. The Idaho Cleanup Project recommends Alternative 3, no action other than continued implementation of existing controls and continued deactivation, decontamination, and dismantlement efforts at the Test Area North/Technical Support Facility

Learning Support Assessment Study of a Computer Simulation for the Development of Microbial Identification Strategies

Directory of Open Access Journals (Sweden)

Tristan E. Johnson

2009-12-01

Full Text Available This paper describes a study that examined how microbiology students construct knowledge of bacterial identification while using a computer simulation. The purpose of this study was to understand how the simulation affects the cognitive processing of students during thinking, problem solving, and learning about bacterial identification and to determine how the simulation facilitates the learning of a domain-specific problem-solving strategy. As part of an upper-division microbiology course, five students participated in several simulation assignments. The data were collected using think-aloud protocol and video action logs as the students used the simulation. The analysis revealed two major themes that determined the performance of the students: Simulation Usage—how the students used the software features and Problem-Solving Strategy Development—the strategy level students started with and the skill level they achieved when they completed their use of the simulation. Several conclusions emerged from the analysis of the data: (i The simulation affects various aspects of cognitive processing by creating an environment that makes it possible to practice the application of a problem-solving strategy. The simulation was used as an environment that allowed students to practice the cognitive skills required to solve an unknown. (ii Identibacter (the computer simulation may be considered to be a cognitive tool to facilitate the learning of a bacterial identification problem-solving strategy. (iii The simulation characteristics did support student learning of a problem-solving strategy. (iv Students demonstrated problem-solving strategy development specific to bacterial identification. (v Participants demonstrated an improved performance from their repeated use of the simulation.

Designing self-monitoring warm-up strategy with blog-based learning system to support knowledge building

Directory of Open Access Journals (Sweden)

James Chan

2012-03-01

Full Text Available Preparing lessons before class is widely recognized as an effective means of increasing student motivation for classroom activities and learning outcome. However, the unclear status of lesson preparation generally discourages teachers and students from maintaining this effective learning strategy. This study applied the self-explanation theory and reading comprehension strategies to design a lesson warm-up mechanism that scaffolds knowledge building. A set of corresponding supporting tools were developed into a blog-based learning system (BBLS to implement the warm-up process. Results of a teaching experiment reveal positive effects of the tools on learning achievement, recall of old knowledge, connection between old and new knowledge, and understanding of new knowledge.

Demonstrating Reliable High Level Waste Slurry Sampling Techniques to Support Hanford Waste Processing

Energy Technology Data Exchange (ETDEWEB)

Kelly, Steven E.

2013-11-11

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capability using simulated Hanford High-Level Waste (HL W) formulations. This work represents one of the remaining technical issues with the high-level waste treatment mission at Hanford. The TOC must demonstrate the ability to adequately mix and sample high-level waste feed to meet the WTP Waste Acceptance Criteria and Data Quality Objectives. The sampling method employed must support both TOC and WTP requirements. To facilitate information transfer between the two facilities the mixing and sampling demonstrations are led by the One System Integrated Project Team. The One System team, Waste Feed Delivery Mixing and Sampling Program, has developed a full scale sampling loop to demonstrate sampler capability. This paper discusses the full scale sampling loops ability to meet precision and accuracy requirements, including lessons learned during testing. Results of the testing showed that the Isolok(R) sampler chosen for implementation provides precise, repeatable results. The Isolok(R) sampler accuracy as tested did not meet test success criteria. Review of test data and the test platform following testing by a sampling expert identified several issues regarding the sampler used to provide reference material used to judge the Isolok's accuracy. Recommendations were made to obtain new data to evaluate the sampler's accuracy utilizing a reference sampler that follows good sampling protocol.

Demonstrating Reliable High Level Waste Slurry Sampling Techniques to Support Hanford Waste Processing

International Nuclear Information System (INIS)

Kelly, Steven E.

2013-01-01

The Hanford Tank Operations Contractor (TOC) and the Hanford Waste Treatment and Immobilization Plant (WTP) contractor are both engaged in demonstrating mixing, sampling, and transfer system capability using simulated Hanford High-Level Waste (HL W) formulations. This work represents one of the remaining technical issues with the high-level waste treatment mission at Hanford. The TOC must demonstrate the ability to adequately mix and sample high-level waste feed to meet the WTP Waste Acceptance Criteria and Data Quality Objectives. The sampling method employed must support both TOC and WTP requirements. To facilitate information transfer between the two facilities the mixing and sampling demonstrations are led by the One System Integrated Project Team. The One System team, Waste Feed Delivery Mixing and Sampling Program, has developed a full scale sampling loop to demonstrate sampler capability. This paper discusses the full scale sampling loops ability to meet precision and accuracy requirements, including lessons learned during testing. Results of the testing showed that the Isolok(R) sampler chosen for implementation provides precise, repeatable results. The Isolok(R) sampler accuracy as tested did not meet test success criteria. Review of test data and the test platform following testing by a sampling expert identified several issues regarding the sampler used to provide reference material used to judge the Isolok's accuracy. Recommendations were made to obtain new data to evaluate the sampler's accuracy utilizing a reference sampler that follows good sampling protocol

Biometeorology - a science supporting adaptation strategies

Science.gov (United States)

Matzarakis, A.; Cegnar, T.

2010-09-01

Biometeorology as an interdisciplinary science deals with the interactions between atmospheric processes and living organisms (plants, animals and humans). If and in what way weather and climate affect the well-being of all the living creatures? This is the most important question biometeorology is answering. The International Society of Biometeorology (ISB) has built an international forum for the promotion of interdisciplinary collaboration between meteorologists, health professionals, biologists, climatologists, ecologists and other scientists. The Society acts as a community of scientists with similar interests, and fulfills an important role in providing information, expertise and advice for international organizations requiring this assistance. The ISB represents the most comprehensive organization, which brings together people with expertise in these areas. Another specific aim of the ISB is the stimulation of research. Therefore, groups of members are working on several topics organized in commissions for specific targets. The recent five commissions are working in the several fields including climate change issues. Some of examples will be presented, which have been initiated by the members of the ISB and how they can be included as a solid scientific basis to develop efficient adaptation strategies. One such example is a project combining natural and social sciences (in the fields of cooperation processes, tourism analysis and strategy, weather and climate change analysis, information and communication and knowledge transfer) in a transdisciplinary approach that includes players from tourism policy and business and which focuses on the North Sea Coast and the Black Forest. The project "Climate trends and sustainable development of tourism in coastal and mountain range regions was divided into four phases - diagnosis, assessment, strategy/design of solutions, and evaluation - where scientific subprojects and practical partners meet regularly to discuss the

Interactive Control System, Intended Strategy, Implemented Strategy dan Emergent Strategy

OpenAIRE

Tubagus Ismail; Darjat Sudrajat

2012-01-01

The purpose of this study was to examine the relationship between management control system (MCS) and strategy formation processes, namely: intended strategy, emergent strategy and impelemented strategy. The focus of MCS in this study was interactive control system. The study was based on Structural Equation Modeling (SEM) as its multivariate analyses instrument. The samples were upper middle managers of manufacturing company in Banten Province, DKI Jakarta Province and West Java Province. AM...

Evaluation of 5-FU pharmacokinetics in cancer patients with DPD deficiency using a Bayesian limited sampling strategy

NARCIS (Netherlands)

Van Kuilenburg, A.; Hausler, P.; Schalhorn, A.; Tanck, M.; Proost, J.H.; Terborg, C.; Behnke, D.; Schwabe, W.; Jabschinsky, K.; Maring, J.G.

Aims: Dihydropyrimidine dehydrogenase (DPD) is the initial enzyme in the catabolism of 5-fluorouracil (5FU) and DPD deficiency is an important pharmacogenetic syndrome. The main purpose of this study was to develop a limited sampling strategy to evaluate the pharmacokinetics of 5FU and to detect

Lifetime Prevalence of Suicide Attempts Among Sexual Minority Adults by Study Sampling Strategies: A Systematic Review and Meta-Analysis.

Science.gov (United States)

Hottes, Travis Salway; Bogaert, Laura; Rhodes, Anne E; Brennan, David J; Gesink, Dionne

2016-05-01

Previous reviews have demonstrated a higher risk of suicide attempts for lesbian, gay, and bisexual (LGB) persons (sexual minorities), compared with heterosexual groups, but these were restricted to general population studies, thereby excluding individuals sampled through LGB community venues. Each sampling strategy, however, has particular methodological strengths and limitations. For instance, general population probability studies have defined sampling frames but are prone to information bias associated with underreporting of LGB identities. By contrast, LGB community surveys may support disclosure of sexuality but overrepresent individuals with strong LGB community attachment. To reassess the burden of suicide-related behavior among LGB adults, directly comparing estimates derived from population- versus LGB community-based samples. In 2014, we searched MEDLINE, EMBASE, PsycInfo, CINAHL, and Scopus databases for articles addressing suicide-related behavior (ideation, attempts) among sexual minorities. We selected quantitative studies of sexual minority adults conducted in nonclinical settings in the United States, Canada, Europe, Australia, and New Zealand. Random effects meta-analysis and meta-regression assessed for a difference in prevalence of suicide-related behavior by sample type, adjusted for study or sample-level variables, including context (year, country), methods (medium, response rate), and subgroup characteristics (age, gender, sexual minority construct). We examined residual heterogeneity by using τ(2). We pooled 30 cross-sectional studies, including 21,201 sexual minority adults, generating the following lifetime prevalence estimates of suicide attempts: 4% (95% confidence interval [CI] = 3%, 5%) for heterosexual respondents to population surveys, 11% (95% CI = 8%, 15%) for LGB respondents to population surveys, and 20% (95% CI = 18%, 22%) for LGB respondents to community surveys (Figure 1). The difference in LGB estimates by sample

Coping Strategies Used by Syrian Refugees in Jordan.

Science.gov (United States)

Alzoubi, Fatmeh Ahmad; Al-Smadi, Ahmed Mohammad; Gougazeh, Yazeed Mohammad

2017-12-01

This study examined the coping strategies used by Syrian refugees in Jordan in relation to their demographics. A cross-sectional correlational study was conducted with a convenient sample of 550 Syrian refugees. Out of all the study participants, 88% reported seeking social support, 64.5% reported using avoidance, and 39.5% reported using problem solving. Participants who were male, single, and younger, and who had a higher education and a higher total income were satisfied with their income, were employed and free of chronic illnesses, and had higher problem-solving scores. Higher social support-seeking scores were associated with being female, older, and widowed; having a lower education and lower total income; being dissatisfied with their income; being nonemployed; and having chronic illnesses. A number of significant predictors were identified for each coping strategy. The results of this study could be used to formulate programs and develop services regarding the stressors encountered by Syrian refugees and their coping strategies.

The Relationship Between Perceived Family Support and Depressive Symptoms in Adolescence: What is the Moderating Role of Coping Strategies and Gender?

Science.gov (United States)

Hickey, Emma; Fitzgerald, Amanda; Dooley, Barbara

2017-05-01

This study examined the moderating role of gender and coping strategies in the relationship between perceived family support, self-esteem and depressive symptoms. Data were used from the My World Survey Second Level (MWS-SL), a national survey of mental health among 6062 young people aged 12-19 years. Conditional process analyses indicated that planned coping moderated the relationship between perceived family support and depressive symptoms for those engaging in low-moderate levels but not high levels of planned coping, and this moderating role was stronger for females than males. Avoidance coping was a moderator for those engaging in moderate-high but not low levels of avoidance coping, and gender also moderated this relationship. Support-focused coping only moderated the perceived family support/depressive symptoms relationship for females. Findings suggest that the strength of the relationship between perceived family support and depressive symptoms depends on level of engagement with a particular coping strategy, and this engagement is a consistently stronger moderator for females.

Sample Curation in Support of the OSIRIS-REx Asteroid Sample Return Mission

Science.gov (United States)

Righter, Kevin; Nakamura-Messenger, Keiko

2017-01-01

The OSIRIS-REx asteroid sample return mission launched to asteroid Bennu Sept. 8, 2016. The spacecraft will arrive at Bennu in late 2019, orbit and map the asteroid, and perform a touch and go (TAG) sampling maneuver in July 2020. After sample is stowed and confirmed the spacecraft will return to Earth, and the sample return capsule (SRC) will land in Utah in September 2023. Samples will be recovered from Utah [2] and then transported and stored in a new sample cleanroom at NASA Johnson Space Center in Houston [3]. The materials curated for the mission are described here. a) Materials Archive and Witness Plate Collection: The SRC and TAGSAM were built between March 2014 and Summer of 2015, and instruments (OTES,OVIRS, OLA, OCAMS, REXIS) were integrated from Summer 2015 until May 2016. A total of 395 items were received for the materials archive at NASA-JSC, with archiving finishing 30 days after launch (with the final archived items being related to launch operations)[4]. The materials fall into several general categories including metals (stainless steel, aluminum, titanium alloys, brass and BeCu alloy), epoxies, paints, polymers, lubricants, non-volatile-residue samples (NVR), sapphire, and various miscellaneous materials. All through the ATLO process (from March 2015 until late August 2016) contamination knowledge witness plates (Si wafer and Al foil) were deployed in the various cleanrooms in Denver and KSC to provide an additional record of particle counts and volatiles that is archived for current and future scientific studies. These plates were deployed in roughly monthly increments with each unit containing 4 Si wafers and 4 Al foils. We archived 128 individual witness plates (64 Si wafers and 64 Al foils); one of each witness plate (Si and Al) was analyzed immediately by the science team after archiving, while the remaining 3 of each are archived indefinitely. Information about each material archived is stored in an extensive database at NASA-JSC, and key

Limited sampling strategies drawn within 3 hours postdose poorly predict mycophenolic acid area-under-the-curve after enteric-coated mycophenolate sodium.

NARCIS (Netherlands)

Winter, B.C. de; Gelder, T. van; Mathôt, R.A.A.; Glander, P.; Tedesco-Silva, H.; Hilbrands, L.B.; Budde, K.; Hest, R.M. van

2009-01-01

Previous studies predicted that limited sampling strategies (LSS) for estimation of mycophenolic acid (MPA) area-under-the-curve (AUC(0-12)) after ingestion of enteric-coated mycophenolate sodium (EC-MPS) using a clinically feasible sampling scheme may have poor predictive performance. Failure of

Wilderness medicine: strategies for provision of medical support for adventure racing.

Science.gov (United States)

Townes, David A

2005-01-01

In adventure racing, or multisporting, athletes perform multiple disciplines over a course in rugged, often remote, wilderness terrain. Disciplines may include, but are not limited to, hiking, trail running, mountain biking, caving, technical climbing, fixed-line mountaineering, flat- and white-water boating, and orienteering. While sprint races may be as short as 6 hours, expedition-length adventure races last a minimum of 36 hours up to 10 days or more and may cover hundreds of kilometres. Over the past decade, adventure racing has grown in popularity throughout the world with increasing numbers of events and participants each year. The provision of on-site medical care during these events is essential to ensure the health and safety of the athletes and thus the success of the sport. At present, there are no formal guidelines and a relatively small amount of literature to assist in the development of medical support plans for these events. This article provides an introduction to the provision of medical support for adventure races. Since a wide variety of illness and injury occur during these events, the medical support plan should provide for proper personnel, equipment and supplies to provide care for a wide range of illness and injury. Foot-related problems are the most common reasons for athletes to require medical attention during these events. This article also highlights some of the controversies involved in the provision of medical support for these events. Suggested penalties for acceptance of medical care during the event and strategies for removal of an athlete from the event for medical reasons are offered. In addition, some of the challenges involved in the provision of medical support, including communication, logistics and liability are discussed. This information should prove useful for medical directors of future, similar events. Because of their extreme nature, expedition-length adventure races represent a new and unique area of wilderness and

Reproducibility of R-fMRI metrics on the impact of different strategies for multiple comparison correction and sample sizes.

Science.gov (United States)

Chen, Xiao; Lu, Bin; Yan, Chao-Gan

2018-01-01

Concerns regarding reproducibility of resting-state functional magnetic resonance imaging (R-fMRI) findings have been raised. Little is known about how to operationally define R-fMRI reproducibility and to what extent it is affected by multiple comparison correction strategies and sample size. We comprehensively assessed two aspects of reproducibility, test-retest reliability and replicability, on widely used R-fMRI metrics in both between-subject contrasts of sex differences and within-subject comparisons of eyes-open and eyes-closed (EOEC) conditions. We noted permutation test with Threshold-Free Cluster Enhancement (TFCE), a strict multiple comparison correction strategy, reached the best balance between family-wise error rate (under 5%) and test-retest reliability/replicability (e.g., 0.68 for test-retest reliability and 0.25 for replicability of amplitude of low-frequency fluctuations (ALFF) for between-subject sex differences, 0.49 for replicability of ALFF for within-subject EOEC differences). Although R-fMRI indices attained moderate reliabilities, they replicated poorly in distinct datasets (replicability < 0.3 for between-subject sex differences, < 0.5 for within-subject EOEC differences). By randomly drawing different sample sizes from a single site, we found reliability, sensitivity and positive predictive value (PPV) rose as sample size increased. Small sample sizes (e.g., < 80 [40 per group]) not only minimized power (sensitivity < 2%), but also decreased the likelihood that significant results reflect "true" effects (PPV < 0.26) in sex differences. Our findings have implications for how to select multiple comparison correction strategies and highlight the importance of sufficiently large sample sizes in R-fMRI studies to enhance reproducibility. Hum Brain Mapp 39:300-318, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Interim Control Strategy for the Test Area North/Technical Support Facility Sewage Treatment Facility Disposal Pond - Two-year Update

Energy Technology Data Exchange (ETDEWEB)

L. V. Street

2007-04-01

The Idaho Cleanup Project has prepared this interim control strategy for the U.S. Department of Energy Idaho Operations Office pursuant to DOE Order 5400.5, Chapter 11.3e (1) to support continued discharges to the Test Area North/Technical Support Facility Sewage Treatment Facility Disposal Pond. In compliance with DOE Order 5400.5, a 2-year review of the Interim Control Strategy document has been completed. This submittal documents the required review of the April 2005 Interim Control Strategy. The Idaho Cleanup Project's recommendation is unchanged from the original recommendation. The Interim Control Strategy evaluates three alternatives: (1) re-route the discharge outlet to an uncontaminated area of the TSF-07; (2) construct a new discharge pond; or (3) no action based on justification for continued use. Evaluation of Alternatives 1 and 2 are based on the estimated cost and implementation timeframe weighed against either alternative's minimal increase in protection of workers, the public, and the environment. Evaluation of Alternative 3, continued use of the TSF-07 Disposal Pond under current effluent controls, is based on an analysis of four points: - Record of Decision controls will protect workers and the public - Risk of increased contamination is low - Discharge water will be eliminated in the foreseeable future - Risk of contamination spread is acceptable. The Idaho Cleanup Project recommends Alternative 3, no action other than continued implementation of existing controls and continued deactivation, decontamination, and dismantlement efforts at the Test Area North/Technical Support Facility.

Evaluating sampling strategy for DNA barcoding study of coastal and inland halo-tolerant Poaceae and Chenopodiaceae: A case study for increased sample size.

Science.gov (United States)

Yao, Peng-Cheng; Gao, Hai-Yan; Wei, Ya-Nan; Zhang, Jian-Hang; Chen, Xiao-Yong; Li, Hong-Qing

2017-01-01

Environmental conditions in coastal salt marsh habitats have led to the development of specialist genetic adaptations. We evaluated six DNA barcode loci of the 53 species of Poaceae and 15 species of Chenopodiaceae from China's coastal salt marsh area and inland area. Our results indicate that the optimum DNA barcode was ITS for coastal salt-tolerant Poaceae and matK for the Chenopodiaceae. Sampling strategies for ten common species of Poaceae and Chenopodiaceae were analyzed according to optimum barcode. We found that by increasing the number of samples collected from the coastal salt marsh area on the basis of inland samples, the number of haplotypes of Arundinella hirta, Digitaria ciliaris, Eleusine indica, Imperata cylindrica, Setaria viridis, and Chenopodium glaucum increased, with a principal coordinate plot clearly showing increased distribution points. The results of a Mann-Whitney test showed that for Digitaria ciliaris, Eleusine indica, Imperata cylindrica, and Setaria viridis, the distribution of intraspecific genetic distances was significantly different when samples from the coastal salt marsh area were included (P Imperata cylindrica and Chenopodium album, average intraspecific distance tended to reach stability. These results indicate that the sample size for DNA barcode of globally distributed species should be increased to 11-15.

Software Process Improvement: Supporting the Linking of the Software and the Business Strategies

Science.gov (United States)

Albuquerque, Adriano Bessa; Rocha, Ana Regina; Lima, Andreia Cavalcanti

The market is becoming more and more competitive, a lot of products and services depend of the software product and the software is one of the most important assets, which influence the organizations’ businesses. Considering this context, we can observe that the companies must to deal with the software, developing or acquiring, carefully. One of the perspectives that can help to take advantage of the software, supporting effectively the business, is to invest on the organization’s software processes. This paper presents an approach to evaluate and improve the processes assets of the software organizations, based on internationally well-known standards and process models. This approach is supported by automated tools from the TABA Workstation and is part of a wider improvement strategy constituted of three layers (organizational layer, process execution layer and external entity layer). Moreover, this paper presents the experience of use and their results.

From buzzword to business strategy: the case for information and decision support systems in e-healthcare.

Science.gov (United States)

Korukonda, Appa Rao; Korukonda, Saritha

2006-01-01

Although electronic healthcare can boast of a remarkable origin in modern-day e-commerce in the form of Electronic Data Interchange (EDI), its mission-critical nature in information-based strategising is yet to be realised. Restricting the scope of e-healthcare management to product advertisements and website management reflects an unfortunate trend of underutilisation of the scope of electronic decision support systems in pricing and other business strategies. This paper aims to illustrate how this trend can be corrected by transforming e-healthcare into a full-fledged business strategy for strategic positioning and corporate profitability. This argument is illustrated with the aid of a business example related to transfer pricing.

Standard methods for sampling and sample preparation for gamma spectroscopy

International Nuclear Information System (INIS)

Taskaeva, M.; Taskaev, E.; Nikolov, P.

1993-01-01

The strategy for sampling and sample preparation is outlined: necessary number of samples; analysis and treatment of the results received; quantity of the analysed material according to the radionuclide concentrations and analytical methods; the minimal quantity and kind of the data needed for making final conclusions and decisions on the base of the results received. This strategy was tested in gamma spectroscopic analysis of radionuclide contamination of the region of Eleshnitsa Uranium Mines. The water samples was taken and stored according to the ASTM D 3370-82. The general sampling procedures were in conformity with the recommendations of ISO 5667. The radionuclides was concentrated by coprecipitation with iron hydroxide and ion exchange. The sampling of soil samples complied with the rules of ASTM C 998, and their sample preparation - with ASTM C 999. After preparation the samples were sealed hermetically and measured. (author)

Development of 87Sr/86Sr maps as targeted strategy to support wine quality.

Science.gov (United States)

Durante, Caterina; Bertacchini, Lucia; Cocchi, Marina; Manzini, Daniela; Marchetti, Andrea; Rossi, Maria Cecilia; Sighinolfi, Simona; Tassi, Lorenzo

2018-07-30

This study summarizes the results obtained from a systematic and long-term project aimed at the development of tools to assess the provenance of food in the oenological sector. In particular, 87 Sr/ 86 Sr isotope ratios were measured on statistically representative set of soils, vine branches and wines sampled in the production district of Modena, worldwide known for the Lambrusco wines production. The obtained data were used to build strontium isotopic maps able to objectively support the Lambrusco PDO wines origin as well as other products of the Modena district. Finally, a strong relationship was found between the 87 Sr/ 86 Sr isotope ratios of soils and vine branches on a large scale, highlighting and confirming once more the idea that plants can also represent an optimal sampling device to support geographical traceability. Copyright © 2018 Elsevier Ltd. All rights reserved.

Maternal depression and parenting in early childhood: Contextual influence of marital quality and social support in two samples.

Science.gov (United States)

Taraban, Lindsay; Shaw, Daniel S; Leve, Leslie D; Wilson, Melvin N; Dishion, Thomas J; Natsuaki, Misaki N; Neiderhiser, Jenae M; Reiss, David

2017-03-01

Marital quality and social support satisfaction were tested as moderators of the association between maternal depressive symptoms and parenting during early childhood (18-36 months) among 2 large, divergent, longitudinal samples (n = 526; n = 570). Unexpectedly, in both samples the association between maternal depressive symptoms and reduced parenting quality was strongest in the context of high marital quality and high social support, and largely nonsignificant in the context of low marital quality and low social support. Possible explanations for these surprising findings are discussed. Results point to the importance of accounting for factors in the broader family context in predicting the association between depressive symptoms and maternal parenting. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Sampling Strategies and Processing of Biobank Tissue Samples from Porcine Biomedical Models.

Science.gov (United States)

Blutke, Andreas; Wanke, Rüdiger

2018-03-06

In translational medical research, porcine models have steadily become more popular. Considering the high value of individual animals, particularly of genetically modified pig models, and the often-limited number of available animals of these models, establishment of (biobank) collections of adequately processed tissue samples suited for a broad spectrum of subsequent analyses methods, including analyses not specified at the time point of sampling, represent meaningful approaches to take full advantage of the translational value of the model. With respect to the peculiarities of porcine anatomy, comprehensive guidelines have recently been established for standardized generation of representative, high-quality samples from different porcine organs and tissues. These guidelines are essential prerequisites for the reproducibility of results and their comparability between different studies and investigators. The recording of basic data, such as organ weights and volumes, the determination of the sampling locations and of the numbers of tissue samples to be generated, as well as their orientation, size, processing and trimming directions, are relevant factors determining the generalizability and usability of the specimen for molecular, qualitative, and quantitative morphological analyses. Here, an illustrative, practical, step-by-step demonstration of the most important techniques for generation of representative, multi-purpose biobank specimen from porcine tissues is presented. The methods described here include determination of organ/tissue volumes and densities, the application of a volume-weighted systematic random sampling procedure for parenchymal organs by point-counting, determination of the extent of tissue shrinkage related to histological embedding of samples, and generation of randomly oriented samples for quantitative stereological analyses, such as isotropic uniform random (IUR) sections generated by the "Orientator" and "Isector" methods, and vertical

Sampling strategies to capture single-cell heterogeneity

OpenAIRE

Satwik Rajaram; Louise E. Heinrich; John D. Gordan; Jayant Avva; Kathy M. Bonness; Agnieszka K. Witkiewicz; James S. Malter; Chloe E. Atreya; Robert S. Warren; Lani F. Wu; Steven J. Altschuler

2017-01-01

Advances in single-cell technologies have highlighted the prevalence and biological significance of cellular heterogeneity. A critical question is how to design experiments that faithfully capture the true range of heterogeneity from samples of cellular populations. Here, we develop a data-driven approach, illustrated in the context of image data, that estimates the sampling depth required for prospective investigations of single-cell heterogeneity from an existing collection of samples. ...

A test of the domain-specific acculturation strategy hypothesis.

Science.gov (United States)

Miller, Matthew J; Yang, Minji; Lim, Robert H; Hui, Kayi; Choi, Na-Yeun; Fan, Xiaoyan; Lin, Li-Ling; Grome, Rebekah E; Farrell, Jerome A; Blackmon, Sha'kema

2013-01-01

Acculturation literature has evolved over the past several decades and has highlighted the dynamic ways in which individuals negotiate experiences in multiple cultural contexts. The present study extends this literature by testing M. J. Miller and R. H. Lim's (2010) domain-specific acculturation strategy hypothesis-that individuals might use different acculturation strategies (i.e., assimilated, bicultural, separated, and marginalized strategies; J. W. Berry, 2003) across behavioral and values domains-in 3 independent cluster analyses with Asian American participants. Present findings supported the domain-specific acculturation strategy hypothesis as 67% to 72% of participants from 3 independent samples using different strategies across behavioral and values domains. Consistent with theory, a number of acculturation strategy cluster group differences emerged across generational status, acculturative stress, mental health symptoms, and attitudes toward seeking professional psychological help. Study limitations and future directions for research are discussed.

Development of improved space sampling strategies for ocean chemical properties: Total carbon dioxide and dissolved nitrate

Science.gov (United States)

Goyet, Catherine; Davis, Daniel; Peltzer, Edward T.; Brewer, Peter G.

1995-01-01

Large-scale ocean observing programs such as the Joint Global Ocean Flux Study (JGOFS) and the World Ocean Circulation Experiment (WOCE) today, must face the problem of designing an adequate sampling strategy. For ocean chemical variables, the goals and observing technologies are quite different from ocean physical variables (temperature, salinity, pressure). We have recently acquired data on the ocean CO2 properties on WOCE cruises P16c and P17c that are sufficiently dense to test for sampling redundancy. We use linear and quadratic interpolation methods on the sampled field to investigate what is the minimum number of samples required to define the deep ocean total inorganic carbon (TCO2) field within the limits of experimental accuracy (+/- 4 micromol/kg). Within the limits of current measurements, these lines were oversampled in the deep ocean. Should the precision of the measurement be improved, then a denser sampling pattern may be desirable in the future. This approach rationalizes the efficient use of resources for field work and for estimating gridded (TCO2) fields needed to constrain geochemical models.

Sampling Strategies for Evaluating the Rate of Adventitious Transgene Presence in Non-Genetically Modified Crop Fields.

Science.gov (United States)

Makowski, David; Bancal, Rémi; Bensadoun, Arnaud; Monod, Hervé; Messéan, Antoine

2017-09-01

According to E.U. regulations, the maximum allowable rate of adventitious transgene presence in non-genetically modified (GM) crops is 0.9%. We compared four sampling methods for the detection of transgenic material in agricultural non-GM maize fields: random sampling, stratified sampling, random sampling + ratio reweighting, random sampling + regression reweighting. Random sampling involves simply sampling maize grains from different locations selected at random from the field concerned. The stratified and reweighting sampling methods make use of an auxiliary variable corresponding to the output of a gene-flow model (a zero-inflated Poisson model) simulating cross-pollination as a function of wind speed, wind direction, and distance to the closest GM maize field. With the stratified sampling method, an auxiliary variable is used to define several strata with contrasting transgene presence rates, and grains are then sampled at random from each stratum. With the two methods involving reweighting, grains are first sampled at random from various locations within the field, and the observations are then reweighted according to the auxiliary variable. Data collected from three maize fields were used to compare the four sampling methods, and the results were used to determine the extent to which transgene presence rate estimation was improved by the use of stratified and reweighting sampling methods. We found that transgene rate estimates were more accurate and that substantially smaller samples could be used with sampling strategies based on an auxiliary variable derived from a gene-flow model. © 2017 Society for Risk Analysis.

Support vector regression to predict porosity and permeability: Effect of sample size

Science.gov (United States)

Al-Anazi, A. F.; Gates, I. D.

2012-02-01

Porosity and permeability are key petrophysical parameters obtained from laboratory core analysis. Cores, obtained from drilled wells, are often few in number for most oil and gas fields. Porosity and permeability correlations based on conventional techniques such as linear regression or neural networks trained with core and geophysical logs suffer poor generalization to wells with only geophysical logs. The generalization problem of correlation models often becomes pronounced when the training sample size is small. This is attributed to the underlying assumption that conventional techniques employing the empirical risk minimization (ERM) inductive principle converge asymptotically to the true risk values as the number of samples increases. In small sample size estimation problems, the available training samples must span the complexity of the parameter space so that the model is able both to match the available training samples reasonably well and to generalize to new data. This is achieved using the structural risk minimization (SRM) inductive principle by matching the capability of the model to the available training data. One method that uses SRM is support vector regression (SVR) network. In this research, the capability of SVR to predict porosity and permeability in a heterogeneous sandstone reservoir under the effect of small sample size is evaluated. Particularly, the impact of Vapnik's ɛ-insensitivity loss function and least-modulus loss function on generalization performance was empirically investigated. The results are compared to the multilayer perception (MLP) neural network, a widely used regression method, which operates under the ERM principle. The mean square error and correlation coefficients were used to measure the quality of predictions. The results demonstrate that SVR yields consistently better predictions of the porosity and permeability with small sample size than the MLP method. Also, the performance of SVR depends on both kernel function

Myeloma: update on supportive care strategies.

Science.gov (United States)

San Miguel, Jesús F; García-Sanz, Ramón

2003-06-01

Despite substantial innovations in the treatment of multiple myeloma (MM), it remains an incurable disease. In addition, it is debatable whether the progress in survival is attributable simply to the therapy used to destroy the tumor clone or if it is also because of therapy designed to ameliorate disease complications. Supportive therapy has evolved greatly alongside general supportive measures used in hematologic malignancies (such as new antibiotics, antifungal agents, and growth factors) in addition to better indications in complementary treatments such as radiotherapy, dialysis, and surgery. However, in MM, several specific adjuvant therapies have also been introduced (eg, bisphosphonates and erythroid-stimulating factors), which have conferred a key role to supportive therapy in the general treatment of patients with MM.

Online Social Support for Patients with Multiple Sclerosis: A Thematic Analysis of Messages Posted to a Virtual Support Community

Directory of Open Access Journals (Sweden)

Masoumeh Abbasi Shavazi

2016-07-01

Full Text Available Background: Currently with the emergence of the Internet, patients have an opportunity to exchange social support online. However, little attention has been devoted to different dimensions of online social support exchanged in virtual support communities for patients with multiple sclerosis (MS. Methods: To provide a rich insight, the aim of this qualitative study was to explore and categorize different dimensions of online social support in messages exchanged in a virtual support community for patients with MS. A total of 548 posted messages created during one year period were selected using purposive sampling to consider the maximum variation sampling. Prior-research-driven thematic analysis was then conducted. In this regard, we used the Cutruna and Suhr’s coding system. The messages that could not be categorized with the used coding system were thematically analyzed to explore new additional social support themes. Results: The results showed that various forms of social support including informational, emotional, network, esteem and tangible support were exchanged. Moreover, new additional social support themes including sharing personal experiences, sharing coping strategies and spiritual support emerged in this virtual support community. Conclusion: The wide range of online social support exchanged in the virtual support community can be regarded as a supplementary source of social support for patients with MS. Future researches can examine online social support more comprehensively considering additional social support themes emerging in the present study.

Standard operating procedures for collection of soil and sediment samples for the Sediment-bound Contaminant Resiliency and Response (SCoRR) strategy pilot study

Science.gov (United States)

Fisher, Shawn C.; Reilly, Timothy J.; Jones, Daniel K.; Benzel, William M.; Griffin, Dale W.; Loftin, Keith A.; Iwanowicz, Luke R.; Cohl, Jonathan A.

2015-12-17

An understanding of the effects on human and ecological health brought by major coastal storms or flooding events is typically limited because of a lack of regionally consistent baseline and trends data in locations proximal to potential contaminant sources and mitigation activities, sensitive ecosystems, and recreational facilities where exposures are probable. In an attempt to close this gap, the U.S. Geological Survey (USGS) has implemented the Sediment-bound Contaminant Resiliency and Response (SCoRR) strategy pilot study to collect regional sediment-quality data prior to and in response to future coastal storms. The standard operating procedure (SOP) detailed in this document serves as the sample-collection protocol for the SCoRR strategy by providing step-by-step instructions for site preparation, sample collection and processing, and shipping of soil and surficial sediment (for example, bed sediment, marsh sediment, or beach material). The objectives of the SCoRR strategy pilot study are (1) to create a baseline of soil-, sand-, marsh sediment-, and bed-sediment-quality data from sites located in the coastal counties from Maine to Virginia based on their potential risk of being contaminated in the event of a major coastal storm or flooding (defined as Resiliency mode); and (2) respond to major coastal storms and flooding by reoccupying select baseline sites and sampling within days of the event (defined as Response mode). For both modes, samples are collected in a consistent manner to minimize bias and maximize quality control by ensuring that all sampling personnel across the region collect, document, and process soil and sediment samples following the procedures outlined in this SOP. Samples are analyzed using four USGS-developed screening methods—inorganic geochemistry, organic geochemistry, pathogens, and biological assays—which are also outlined in this SOP. Because the SCoRR strategy employs a multi-metric approach for sample analyses, this

Using the Logistic Regression model in supporting decisions of establishing marketing strategies

Directory of Open Access Journals (Sweden)

Cristinel CONSTANTIN

2015-12-01

Full Text Available This paper is about an instrumental research regarding the using of Logistic Regression model for data analysis in marketing research. The decision makers inside different organisation need relevant information to support their decisions regarding the marketing strategies. The data provided by marketing research could be computed in various ways but the multivariate data analysis models can enhance the utility of the information. Among these models we can find the Logistic Regression model, which is used for dichotomous variables. Our research is based on explanation the utility of this model and interpretation of the resulted information in order to help practitioners and researchers to use it in their future investigations

A nested-PCR strategy for molecular diagnosis of mollicutes in uncultured biological samples from cows with vulvovaginitis.

Science.gov (United States)

Voltarelli, Daniele Cristina; de Alcântara, Brígida Kussumoto; Lunardi, Michele; Alfieri, Alice Fernandes; de Arruda Leme, Raquel; Alfieri, Amauri Alcindo

2018-01-01

Bacteria classified in Mycoplasma (M. bovis and M. bovigenitalium) and Ureaplasma (U. diversum) genera are associated with granular vulvovaginitis that affect heifers and cows at reproductive age. The traditional means for detection and speciation of mollicutes from clinical samples have been culture and serology. However, challenges experienced with these laboratory methods have hampered assessment of their impact in pathogenesis and epidemiology in cattle worldwide. The aim of this study was to develop a PCR strategy to detect and primarily discriminate between the main species of mollicutes associated with reproductive disorders of cattle in uncultured clinical samples. In order to amplify the 16S-23S rRNA internal transcribed spacer region of the genome, a consensual and species-specific nested-PCR assay was developed to identify and discriminate between main species of mollicutes. In addition, 31 vaginal swab samples from dairy and beef affected cows were investigated. This nested-PCR strategy was successfully employed in the diagnosis of single and mixed mollicute infections of diseased cows from cattle herds from Brazil. The developed system enabled the rapid and unambiguous identification of the main mollicute species known to be associated with this cattle reproductive disorder through differential amplification of partial fragments of the ITS region of mollicute genomes. The development of rapid and sensitive tools for mollicute detection and discrimination without the need for previous cultures or sequencing of PCR products is a high priority for accurate diagnosis in animal health. Therefore, the PCR strategy described herein may be helpful for diagnosis of this class of bacteria in genital swabs submitted to veterinary diagnostic laboratories, not demanding expertise in mycoplasma culture and identification. Copyright © 2017 Elsevier B.V. All rights reserved.

Job demands-control-social support model and coping strategies: predicting burnout and wellbeing in a group of Italian nurses.

Science.gov (United States)

Pisanti, R

2012-01-01

Nursing is generally considered to be a stressful profession. The purpose of the present study was to test the core hypotheses of the job demands-control-social support model (JDCS) of Karasek & Theorell (1990). In order to refine and extend the JDCS model, we also analyzed the direct and interactive role of three coping strategies: task- oriented, emotion-oriented, and avoidance-oriented coping. Questionnaire data from 1383 nurses (77%female) were collected. Controlling for demographic variables and non-linearity of the associations between job characteristics and outcomes (job satisfaction; burnout dimensions, psychological distress, and somatic complaints), hierarchical regression analyses indicated that job control and social support combined additively (p < 0.001) with job demands to explain the wellbeing outcomes (explained variance between 6% and 28%). Coping strategies accounted for additional variance (p < 0.001; explained variance between 4% and 15%) in all outcomes except in job satisfaction. Support was found for main effects of coping. Coping strategies did not moderate the impact of job characteristics on burnout and wellbeing. Emotion-oriented coping emerged as the most important predictor and was consistently associated with higher burnout levels and lower wellbeing levels. The results demonstrated the need to include the role of individual variables in the JDCS model. The limitations of the study, and theoretical and practical implications are discussed.

Social support influences on eating awareness in children and adolescents: the mediating effect of self-regulatory strategies.

Science.gov (United States)

Gaspar de Matos, Margarida; Palmeira, Antonio L; Gaspar, Tania; De Wit, John B F; Luszczynska, Aleksandra

2016-01-01

The impact of the social environment on healthy eating awareness results from complex interactions among physical, economic, cultural, interpersonal and individual characteristics. This study investigated the impact of social support and social influence on healthy eating awareness, controlling for socio-economic status, gender and age. Additionally, the mediating effect of self-regulation strategies was examined. A total of 2764 children and adolescents aged 10-17 from four European countries completed self-report measures on healthy eating awareness, social influence and the use of self-regulation strategies. Healthy eating awareness and the use of self-regulation strategies were more likely to occur among younger participants. An interaction between gender and age was related to the use of some self-regulation strategies; compared to girls, boys decreased the use of self-regulation strategies more from pre-adolescence to adolescence. Peer social influence was associated with more unhealthy eating in older participants. Results suggest a need to promote self-regulatory competences among young people in order to assist them with regulating their eating behaviours, especially in the presence of peers. Both school-based interventions and family-based interventions, focusing on self-regulation cognitions and social (peer) influence, could help children and adolescents to use self-regulatory strategies which are essential to eat healthier.

A New Vision for Teacher Professional Growth & Support: Six Steps to a More Powerful School System Strategy

Science.gov (United States)

Education Resource Strategies, 2013

2013-01-01

One of a series of Education Resource Strategies (ERS) publications and tools, this paper explores important ways to organize and invest in Professional Growth & Support that strengthen teaching capacity and effectiveness at the system level. It draws on research, ERS experience with urban school systems nationwide, and detailed analyses of…

Appreciating the difference between design-based and model-based sampling strategies in quantitative morphology of the nervous system.

Science.gov (United States)

Geuna, S

2000-11-20

Quantitative morphology of the nervous system has undergone great developments over recent years, and several new technical procedures have been devised and applied successfully to neuromorphological research. However, a lively debate has arisen on some issues, and a great deal of confusion appears to exist that is definitely responsible for the slow spread of the new techniques among scientists. One such element of confusion is related to uncertainty about the meaning, implications, and advantages of the design-based sampling strategy that characterize the new techniques. In this article, to help remove this uncertainty, morphoquantitative methods are described and contrasted on the basis of the inferential paradigm of the sampling strategy: design-based vs model-based. Moreover, some recommendations are made to help scientists judge the appropriateness of a method used for a given study in relation to its specific goals. Finally, the use of the term stereology to label, more or less expressly, only some methods is critically discussed. Copyright 2000 Wiley-Liss, Inc.

Solid-Phase Extraction Strategies to Surmount Body Fluid Sample Complexity in High-Throughput Mass Spectrometry-Based Proteomics

Science.gov (United States)

Bladergroen, Marco R.; van der Burgt, Yuri E. M.

2015-01-01

For large-scale and standardized applications in mass spectrometry- (MS-) based proteomics automation of each step is essential. Here we present high-throughput sample preparation solutions for balancing the speed of current MS-acquisitions and the time needed for analytical workup of body fluids. The discussed workflows reduce body fluid sample complexity and apply for both bottom-up proteomics experiments and top-down protein characterization approaches. Various sample preparation methods that involve solid-phase extraction (SPE) including affinity enrichment strategies have been automated. Obtained peptide and protein fractions can be mass analyzed by direct infusion into an electrospray ionization (ESI) source or by means of matrix-assisted laser desorption ionization (MALDI) without further need of time-consuming liquid chromatography (LC) separations. PMID:25692071

Evaluating sampling strategy for DNA barcoding study of coastal and inland halo-tolerant Poaceae and Chenopodiaceae: A case study for increased sample size.

Directory of Open Access Journals (Sweden)

Peng-Cheng Yao

Full Text Available Environmental conditions in coastal salt marsh habitats have led to the development of specialist genetic adaptations. We evaluated six DNA barcode loci of the 53 species of Poaceae and 15 species of Chenopodiaceae from China's coastal salt marsh area and inland area. Our results indicate that the optimum DNA barcode was ITS for coastal salt-tolerant Poaceae and matK for the Chenopodiaceae. Sampling strategies for ten common species of Poaceae and Chenopodiaceae were analyzed according to optimum barcode. We found that by increasing the number of samples collected from the coastal salt marsh area on the basis of inland samples, the number of haplotypes of Arundinella hirta, Digitaria ciliaris, Eleusine indica, Imperata cylindrica, Setaria viridis, and Chenopodium glaucum increased, with a principal coordinate plot clearly showing increased distribution points. The results of a Mann-Whitney test showed that for Digitaria ciliaris, Eleusine indica, Imperata cylindrica, and Setaria viridis, the distribution of intraspecific genetic distances was significantly different when samples from the coastal salt marsh area were included (P < 0.01. These results suggest that increasing the sample size in specialist habitats can improve measurements of intraspecific genetic diversity, and will have a positive effect on the application of the DNA barcodes in widely distributed species. The results of random sampling showed that when sample size reached 11 for Chloris virgata, Chenopodium glaucum, and Dysphania ambrosioides, 13 for Setaria viridis, and 15 for Eleusine indica, Imperata cylindrica and Chenopodium album, average intraspecific distance tended to reach stability. These results indicate that the sample size for DNA barcode of globally distributed species should be increased to 11-15.

The Relationship of Acculturation Strategies to Resilience: The Moderating Impact of Social Support among Qiang Ethnicity following the 2008 Chinese Earthquake.

Science.gov (United States)

Han, Li; Berry, John W; Zheng, Yong

2016-01-01

International research has mostly confirmed the positive association between acculturation strategies and resilience in ethnic groups, but the mediating and moderating mechanisms underlying the relationships are still under-investigated. The present study aimed to investigate the associations between acculturation strategies (based on two cultural identities) and resilience of 898 Qiang ethnicity volunteers (mean age = 29.5), especially exploring the mediating and moderating effects of personality, spiritual belief and social support on the relationship between acculturation strategy (using two cultural identities as latent variables in model analysis) and resilience following the occurrence of 2008 Wenchuan earthquake in Sichuan, taking such mechanisms into account. Results were as follows: (1) All variable presented significant positive correlations; (2) Consistent with the mediating hypotheses, personality and spiritual beliefs played a partial mediating role in the relationship between two cultural identities and resilience; (3) High or low level of perceived social support had a moderating effect on cultural identities and resilience; (4) The integration strategy was the most optimal style to promote the development of resilience, but marginalization was the least effective style.

Coping strategies and behavioural changes following a genital herpes diagnosis among an urban sample of underserved Midwestern women.

Science.gov (United States)

Davis, Alissa; Roth, Alexis; Brand, Juanita Ebert; Zimet, Gregory D; Van Der Pol, Barbara

2016-03-01

This study focused on understanding the coping strategies and related behavioural changes of women who were recently diagnosed with herpes simplex virus type 2. In particular, we were interested in how coping strategies, condom use, and acyclovir uptake evolve over time. Twenty-eight women screening positive for herpes simplex virus type 2 were recruited through a public health STD clinic and the Indianapolis Community Court. Participants completed three semi-structured interviews with a woman researcher over a six-month period. The interviews focused on coping strategies for dealing with a diagnosis, frequency of condom use, suppressive and episodic acyclovir use, and the utilisation of herpes simplex virus type 2 support groups. Interview data were analysed using content analysis to identify and interpret concepts and themes that emerged from the interviews. Women employed a variety of coping strategies following an herpes simplex virus type 2 diagnosis. Of the women, 32% reported an increase in religious activities, 20% of women reported an increase in substance use, and 56% of women reported engaging in other coping activities. A total of 80% of women reported abstaining from sex immediately following the diagnosis, but 76% of women reported engaging in sex again by the six-month interview. Condom and medication use did not increase and herpes simplex virus type 2 support groups were not utilised by participants. All participants reported engaging in at least one coping mechanism after receiving their diagnosis. A positive diagnosis did not seem to result in increased use of condoms for the majority of participants and the use of acyclovir was low overall. © The Author(s) 2015.

Ground-water sample collection and analysis plan for the ground-water surveillance project

International Nuclear Information System (INIS)

Bryce, R.W.; Evans, J.C.; Olsen, K.B.

1991-12-01

The Pacific Northwest Laboratory performs ground-water sampling activities at the US Department of Energy's (DOE's) Hanford Site in support of DOE's environmental surveillance responsibilities. The purpose of this document is to translate DOE's General Environmental Protection Program (DOE Order 5400.1) into a comprehensive ground-water sample collection and analysis plan for the Hanford Site. This sample collection and analysis plan sets forth the environmental surveillance objectives applicable to ground water, identifies the strategy for selecting sample collection locations, and lists the analyses to be performed to meet those objectives

Sustained Attention Across the Life Span in a Sample of 10,000: Dissociating Ability and Strategy.

Science.gov (United States)

Fortenbaugh, Francesca C; DeGutis, Joseph; Germine, Laura; Wilmer, Jeremy B; Grosso, Mallory; Russo, Kathryn; Esterman, Michael

2015-09-01

Normal and abnormal differences in sustained visual attention have long been of interest to scientists, educators, and clinicians. Still lacking, however, is a clear understanding of how sustained visual attention varies across the broad sweep of the human life span. In the present study, we filled this gap in two ways. First, using an unprecedentedly large 10,430-person sample, we modeled age-related differences with substantially greater precision than have prior efforts. Second, using the recently developed gradual-onset continuous performance test (gradCPT), we parsed sustained-attention performance over the life span into its ability and strategy components. We found that after the age of 15 years, the strategy and ability trajectories saliently diverge. Strategy becomes monotonically more conservative with age, whereas ability peaks in the early 40s and is followed by a gradual decline in older adults. These observed life-span trajectories for sustained attention are distinct from results of other life-span studies focusing on fluid and crystallized intelligence. © The Author(s) 2015.

[Analysis of Sexual Strategies Theory in the Spanish population].

Science.gov (United States)

Yela, Carlos

2012-02-01

The aim of this study was to test some of the main hypotheses derived from Buss' Sexual Strategies Theory on a representative Spanish sample. These hypotheses refer to the different strategies men and woman seem to adopt when they want to engage in a short-term sexual relationship (fling), or in a long-term one (loving relationship). (The technical term "strategies", unlike its equivalent in everyday language, is not meant to imply something necessarily planned or conscious). Data was obtained by self-report from a representative sample of 1949 Spanish people. Almost all the results verify the working hypotheses, conferring some empirical support on the theory from which they were deduced, within an evolutionary Social Psychology paradigm. In any case, it is argued that socialization approaches ("double moral" and the social construction of gender role and sexual identity) can also explain most of the differences obtained, in perfect compatibility with biological perspectives.

Maternal Depression and Parenting in Early Childhood: Contextual Influence of Marital Quality and Social Support in Two Samples

Science.gov (United States)

Taraban, Lindsay; Shaw, Daniel S.; Leve, Leslie D.; Wilson, Melvin N.; Dishion, Thomas J.; Natsuaki, Misaki N.; Neiderhiser, Jenae M.; Reiss, David

2017-01-01

Marital quality and social support satisfaction were tested as moderators of the association between maternal depressive symptoms and parenting during early childhood (18--36 months) among 2 large, divergent, longitudinal samples (n = 526; n = 570). Unexpectedly, in both samples the association between maternal depressive symptoms and reduced…

Creativity and Strategy Development

DEFF Research Database (Denmark)

Sørensen, Lene Tolstrup; Vidal, Rene Victor Valqui

This paper focus on how creative thinking, processes and methods can support the strategy development and planning process in organisations. First, several fundamental concepts related to both strategy development and planning are stipulated. In addition, the concept of living organisation...... will be discussed as well as the interaction between strategy and creativity. Then, methodological ideas to support the strategy making process are presented enhancing the use of creative methods and tools. Finally, a case study related to the development of a strategy for organisational development using...... creativity tools is discussed....

Radial line-scans as representative sampling strategy in dried-droplet laser ablation of liquid samples deposited on pre-cut filter paper disks

Energy Technology Data Exchange (ETDEWEB)

Nischkauer, Winfried [Institute of Chemical Technologies and Analytics, Vienna University of Technology, Vienna (Austria); Department of Analytical Chemistry, Ghent University, Ghent (Belgium); Vanhaecke, Frank [Department of Analytical Chemistry, Ghent University, Ghent (Belgium); Bernacchi, Sébastien; Herwig, Christoph [Institute of Chemical Engineering, Vienna University of Technology, Vienna (Austria); Limbeck, Andreas, E-mail: Andreas.Limbeck@tuwien.ac.at [Institute of Chemical Technologies and Analytics, Vienna University of Technology, Vienna (Austria)

2014-11-01

Nebulising liquid samples and using the aerosol thus obtained for further analysis is the standard method in many current analytical techniques, also with inductively coupled plasma (ICP)-based devices. With such a set-up, quantification via external calibration is usually straightforward for samples with aqueous or close-to-aqueous matrix composition. However, there is a variety of more complex samples. Such samples can be found in medical, biological, technological and industrial contexts and can range from body fluids, like blood or urine, to fuel additives or fermentation broths. Specialized nebulizer systems or careful digestion and dilution are required to tackle such demanding sample matrices. One alternative approach is to convert the liquid into a dried solid and to use laser ablation for sample introduction. Up to now, this approach required the application of internal standards or matrix-adjusted calibration due to matrix effects. In this contribution, we show a way to circumvent these matrix effects while using simple external calibration for quantification. The principle of representative sampling that we propose uses radial line-scans across the dried residue. This compensates for centro-symmetric inhomogeneities typically observed in dried spots. The effectiveness of the proposed sampling strategy is exemplified via the determination of phosphorus in biochemical fermentation media. However, the universal viability of the presented measurement protocol is postulated. Detection limits using laser ablation-ICP-optical emission spectrometry were in the order of 40 μg mL{sup −1} with a reproducibility of 10 % relative standard deviation (n = 4, concentration = 10 times the quantification limit). The reported sensitivity is fit-for-purpose in the biochemical context described here, but could be improved using ICP-mass spectrometry, if future analytical tasks would require it. Trueness of the proposed method was investigated by cross-validation with

The Effect of Reading Involvement through Open-Ended Strategy vs. Fill-in- the- Blanks Strategy on Young EFL Learners’ Reading Comprehension Ability

Directory of Open Access Journals (Sweden)

Rita Salehi Sepehr

2014-11-01

Full Text Available The present study investigated the extent to which an instructional framework of integrating strategy instruction (open-ended strategy and fill-in-the blanks strategy with motivation- support affected on reading result for young EFL learners. The central area of exploration included a comparison among three approaches to reading instruction: First, fill-in-the blanks strategy intervention; second, open-ended strategy intervention; and last, a control group which received the conventional reading strategies. The participants were sampled from amongst a group of seventy-seven pre-intermediate EFL learners in a language school in Tehran- Iran based on convenient sampling technique. For the sake of measurement, the researchers administered PET and CELT along with reading strategy based-test to quantify the participants’ current level of knowledge as well as the degree of achievement after treatment. For measurement’s sake, different types of tests such as PET, reading comprehension test (CELT, and reading strategy based- test were employed to quantify the participants’ current level of knowledge as well as the degree of achievement before and after instruction. The result of the present study indicated that the experimental groups had a significant improvement over the control group. Also, the level of learners’ reading engagement during classroom work mediated the instructional effects on reading outcomes. The results of this study can be to the benefit of both EFL and ESL teachers to teach reading comprehension using the student's critical mind as well as critical involvement in the reading tasks.

Fate of organic microcontaminants in wastewater treatment and river systems: An uncertainty assessment in view of sampling strategy, and compound consumption rate and degradability.

Science.gov (United States)

Aymerich, I; Acuña, V; Ort, C; Rodríguez-Roda, I; Corominas, Ll

2017-11-15

The growing awareness of the relevance of organic microcontaminants on the environment has led to a growing number of studies on attenuation of these compounds in wastewater treatment plants (WWTP) and rivers. However, the effects of the sampling strategies (frequency and duration of composite samples) on the attenuation estimates are largely unknown. Our goal was to assess how frequency and duration of composite samples influence uncertainty of the attenuation estimates in WWTPs and rivers. Furthermore, we also assessed how compound consumption rate and degradability influence uncertainty. The assessment was conducted through simulating the integrated wastewater system of Puigcerdà (NE Iberian Peninsula) using a sewer pattern generator and a coupled model of WWTP and river. Results showed that the sampling strategy is especially critical at the influent of WWTP, particularly when the number of toilet flushes containing the compound of interest is small (≤100 toilet flushes with compound day -1 ), and less critical at the effluent of the WWTP and in the river due to the mixing effects of the WWTP. For example, at the WWTP, when evaluating a compound that is present in 50 pulses·d -1 using a sampling frequency of 15-min to collect a 24-h composite sample, the attenuation uncertainty can range from 94% (0% degradability) to 9% (90% degradability). The estimation of attenuation in rivers is less critical than in WWTPs, as the attenuation uncertainty was lower than 10% for all evaluated scenarios. Interestingly, the errors in the estimates of attenuation are usually lower than those of loads for most sampling strategies and compound characteristics (e.g. consumption and degradability), although the opposite occurs for compounds with low consumption and inappropriate sampling strategies at the WWTP. Hence, when designing a sampling campaign, one should consider the influence of compounds' consumption and degradability as well as the desired level of accuracy in

Implementing a sub-national strategic framework to reduce the illicit tobacco market to support national strategies

Directory of Open Access Journals (Sweden)

Ailsa Rutter

2018-03-01

The success of this strategic framework demonstrates that activity can be co-ordinated locally or sub-nationally to support national strategies to reduce the illicit tobacco market. Activity should always be placed within the broader context of 'all tobacco kills' and should contain measures to reduce both supply and demand. Useful resources for other programmes and settings can be found at www.illicit-tobacco.co.uk.

The Role of Social Support and Coping Strategies on Mental Health of a Group of Iranian Disabled War Veterans

Directory of Open Access Journals (Sweden)

Abdulaziz Aflakseir

2010-08-01

Full Text Available "n Objective: The purpose of this study was to examine the role of social support on the mental health of disabled war veterans alongside the role of physical disability and deployment type. The second aim of the study was to examine the relationship between coping strategies and mental health. "n Method: 85 disabled Iranian war veterans participated in this study. All of the participants were asked to complete the Medical Outcomes Study (MOS ,Social Support Survey, Impact of Event-Revised Scale (IES-R, Hospital Anxiety and Depression Scale (HADS, The Short Form (SF-36 Health Survey Questionnaire, and Brief COPE Scale. Results: The results showed that social support had a significant contribution on the mental health of the participants above and beyond the physical disability and deployment type. The physical disability also predicted the mental health of veterans, but deployment type did not have any significant contribution on mental health of the participants. The findings also showed that those veterans who used constructive coping strategies had better mental health status . "nConclusion: The findings suggest that after more than twenty years of war, social support still plays an important role in the life of Iranian disabled war veterans.

Actual distribution of Cronobacter spp. in industrial batches of powdered infant formula and consequences for performance of sampling strategies.

Science.gov (United States)

Jongenburger, I; Reij, M W; Boer, E P J; Gorris, L G M; Zwietering, M H

2011-11-15

The actual spatial distribution of microorganisms within a batch of food influences the results of sampling for microbiological testing when this distribution is non-homogeneous. In the case of pathogens being non-homogeneously distributed, it markedly influences public health risk. This study investigated the spatial distribution of Cronobacter spp. in powdered infant formula (PIF) on industrial batch-scale for both a recalled batch as well a reference batch. Additionally, local spatial occurrence of clusters of Cronobacter cells was assessed, as well as the performance of typical sampling strategies to determine the presence of the microorganisms. The concentration of Cronobacter spp. was assessed in the course of the filling time of each batch, by taking samples of 333 g using the most probable number (MPN) enrichment technique. The occurrence of clusters of Cronobacter spp. cells was investigated by plate counting. From the recalled batch, 415 MPN samples were drawn. The expected heterogeneous distribution of Cronobacter spp. could be quantified from these samples, which showed no detectable level (detection limit of -2.52 log CFU/g) in 58% of samples, whilst in the remainder concentrations were found to be between -2.52 and 2.75 log CFU/g. The estimated average concentration in the recalled batch was -2.78 log CFU/g and a standard deviation of 1.10 log CFU/g. The estimated average concentration in the reference batch was -4.41 log CFU/g, with 99% of the 93 samples being below the detection limit. In the recalled batch, clusters of cells occurred sporadically in 8 out of 2290 samples of 1g taken. The two largest clusters contained 123 (2.09 log CFU/g) and 560 (2.75 log CFU/g) cells. Various sampling strategies were evaluated for the recalled batch. Taking more and smaller samples and keeping the total sampling weight constant, considerably improved the performance of the sampling plans to detect such a type of contaminated batch. Compared to random sampling

Supporting Sampling and Sample Preparation Tools for Isotope and Nuclear Analysis

International Nuclear Information System (INIS)

2016-03-01

Nuclear and related techniques can help develop climate-smart agricultural practices by optimizing water and nutrient use efficiency, assessing organic carbon sequestration in soil, and assisting in the evaluation of soil erosion control measures. Knowledge on the behaviour of radioactive materials in soil, water and foodstuffs is also essential in enhancing nuclear emergency preparedness and response. Appropriate sampling and sample preparation are the first steps to ensure the quality and effective use of the measurements and this publication provides comprehensive detail on the necessary steps

A radial sampling strategy for uniform k-space coverage with retrospective respiratory gating in 3D ultrashort-echo-time lung imaging.

Science.gov (United States)

Park, Jinil; Shin, Taehoon; Yoon, Soon Ho; Goo, Jin Mo; Park, Jang-Yeon

2016-05-01

The purpose of this work was to develop a 3D radial-sampling strategy which maintains uniform k-space sample density after retrospective respiratory gating, and demonstrate its feasibility in free-breathing ultrashort-echo-time lung MRI. A multi-shot, interleaved 3D radial sampling function was designed by segmenting a single-shot trajectory of projection views such that each interleaf samples k-space in an incoherent fashion. An optimal segmentation factor for the interleaved acquisition was derived based on an approximate model of respiratory patterns such that radial interleaves are evenly accepted during the retrospective gating. The optimality of the proposed sampling scheme was tested by numerical simulations and phantom experiments using human respiratory waveforms. Retrospectively, respiratory-gated, free-breathing lung MRI with the proposed sampling strategy was performed in healthy subjects. The simulation yielded the most uniform k-space sample density with the optimal segmentation factor, as evidenced by the smallest standard deviation of the number of neighboring samples as well as minimal side-lobe energy in the point spread function. The optimality of the proposed scheme was also confirmed by minimal image artifacts in phantom images. Human lung images showed that the proposed sampling scheme significantly reduced streak and ring artifacts compared with the conventional retrospective respiratory gating while suppressing motion-related blurring compared with full sampling without respiratory gating. In conclusion, the proposed 3D radial-sampling scheme can effectively suppress the image artifacts due to non-uniform k-space sample density in retrospectively respiratory-gated lung MRI by uniformly distributing gated radial views across the k-space. Copyright © 2016 John Wiley & Sons, Ltd.

Peer Support for the Hardly Reached: A Systematic Review.

Science.gov (United States)

Sokol, Rebeccah; Fisher, Edwin

2016-07-01

Health disparities are aggravated when prevention and care initiatives fail to reach those they are intended to help. Groups can be classified as hardly reached according to a variety of circumstances that fall into 3 domains: individual (e.g., psychological factors), demographic (e.g., socioeconomic status), and cultural-environmental (e.g., social network). Several reports have indicated that peer support is an effective means of reaching hardly reached individuals. However, no review has explored peer support effectiveness in relation to the circumstances associated with being hardly reached or across diverse health problems. To conduct a systematic review assessing the reach and effectiveness of peer support among hardly reached individuals, as well as peer support strategies used. Three systematic searches conducted in PubMed identified studies that evaluated peer support programs among hardly reached individuals. In aggregate, the searches covered articles published from 2000 to 2015. Eligible interventions provided ongoing support for complex health behaviors, including prioritization of hardly reached populations, assistance in applying behavior change plans, and social-emotional support directed toward disease management or quality of life. Studies were excluded if they addressed temporally isolated behaviors, were limited to protocol group classes, included peer support as the dependent variable, did not include statistical tests of significance, or incorporated comparison conditions that provided appreciable social support. We abstracted data regarding the primary health topic, categorizations of hardly reached groups, program reach, outcomes, and strategies employed. We conducted a 2-sample t test to determine whether reported strategies were related to reach. Forty-seven studies met our inclusion criteria, and these studies represented each of the 3 domains of circumstances assessed (individual, demographic, and cultural-environmental). Interventions

Radial line-scans as representative sampling strategy in dried-droplet laser ablation of liquid samples deposited on pre-cut filter paper disks.

Science.gov (United States)

Nischkauer, Winfried; Vanhaecke, Frank; Bernacchi, Sébastien; Herwig, Christoph; Limbeck, Andreas

2014-11-01

Nebulising liquid samples and using the aerosol thus obtained for further analysis is the standard method in many current analytical techniques, also with inductively coupled plasma (ICP)-based devices. With such a set-up, quantification via external calibration is usually straightforward for samples with aqueous or close-to-aqueous matrix composition. However, there is a variety of more complex samples. Such samples can be found in medical, biological, technological and industrial contexts and can range from body fluids, like blood or urine, to fuel additives or fermentation broths. Specialized nebulizer systems or careful digestion and dilution are required to tackle such demanding sample matrices. One alternative approach is to convert the liquid into a dried solid and to use laser ablation for sample introduction. Up to now, this approach required the application of internal standards or matrix-adjusted calibration due to matrix effects. In this contribution, we show a way to circumvent these matrix effects while using simple external calibration for quantification. The principle of representative sampling that we propose uses radial line-scans across the dried residue. This compensates for centro-symmetric inhomogeneities typically observed in dried spots. The effectiveness of the proposed sampling strategy is exemplified via the determination of phosphorus in biochemical fermentation media. However, the universal viability of the presented measurement protocol is postulated. Detection limits using laser ablation-ICP-optical emission spectrometry were in the order of 40 μg mL - 1 with a reproducibility of 10 % relative standard deviation (n = 4, concentration = 10 times the quantification limit). The reported sensitivity is fit-for-purpose in the biochemical context described here, but could be improved using ICP-mass spectrometry, if future analytical tasks would require it. Trueness of the proposed method was investigated by cross-validation with

Radial line-scans as representative sampling strategy in dried-droplet laser ablation of liquid samples deposited on pre-cut filter paper disks

Science.gov (United States)

Nischkauer, Winfried; Vanhaecke, Frank; Bernacchi, Sébastien; Herwig, Christoph; Limbeck, Andreas

2014-11-01

Nebulising liquid samples and using the aerosol thus obtained for further analysis is the standard method in many current analytical techniques, also with inductively coupled plasma (ICP)-based devices. With such a set-up, quantification via external calibration is usually straightforward for samples with aqueous or close-to-aqueous matrix composition. However, there is a variety of more complex samples. Such samples can be found in medical, biological, technological and industrial contexts and can range from body fluids, like blood or urine, to fuel additives or fermentation broths. Specialized nebulizer systems or careful digestion and dilution are required to tackle such demanding sample matrices. One alternative approach is to convert the liquid into a dried solid and to use laser ablation for sample introduction. Up to now, this approach required the application of internal standards or matrix-adjusted calibration due to matrix effects. In this contribution, we show a way to circumvent these matrix effects while using simple external calibration for quantification. The principle of representative sampling that we propose uses radial line-scans across the dried residue. This compensates for centro-symmetric inhomogeneities typically observed in dried spots. The effectiveness of the proposed sampling strategy is exemplified via the determination of phosphorus in biochemical fermentation media. However, the universal viability of the presented measurement protocol is postulated. Detection limits using laser ablation-ICP-optical emission spectrometry were in the order of 40 μg mL- 1 with a reproducibility of 10 % relative standard deviation (n = 4, concentration = 10 times the quantification limit). The reported sensitivity is fit-for-purpose in the biochemical context described here, but could be improved using ICP-mass spectrometry, if future analytical tasks would require it. Trueness of the proposed method was investigated by cross-validation with

SOME SYSTEMATIC SAMPLING STRATEGIES USING MULTIPLE RANDOM STARTS

OpenAIRE

Sampath Sundaram; Ammani Sivaraman

2010-01-01

In this paper an attempt is made to extend linear systematic sampling using multiple random starts due to Gautschi(1957)for various types of systematic sampling schemes available in literature, namely(i)  Balanced Systematic Sampling (BSS) of  Sethi (1965) and (ii) Modified Systematic Sampling (MSS) of Singh, Jindal, and Garg  (1968). Further, the proposed methods were compared with Yates corrected estimator developed with reference to Gautschi’s Linear systematic samplin...

GARN: Sampling RNA 3D Structure Space with Game Theory and Knowledge-Based Scoring Strategies.

Science.gov (United States)

Boudard, Mélanie; Bernauer, Julie; Barth, Dominique; Cohen, Johanne; Denise, Alain

2015-01-01

Cellular processes involve large numbers of RNA molecules. The functions of these RNA molecules and their binding to molecular machines are highly dependent on their 3D structures. One of the key challenges in RNA structure prediction and modeling is predicting the spatial arrangement of the various structural elements of RNA. As RNA folding is generally hierarchical, methods involving coarse-grained models hold great promise for this purpose. We present here a novel coarse-grained method for sampling, based on game theory and knowledge-based potentials. This strategy, GARN (Game Algorithm for RNa sampling), is often much faster than previously described techniques and generates large sets of solutions closely resembling the native structure. GARN is thus a suitable starting point for the molecular modeling of large RNAs, particularly those with experimental constraints. GARN is available from: http://garn.lri.fr/.

A sampling-based computational strategy for the representation of epistemic uncertainty in model predictions with evidence theory.

Energy Technology Data Exchange (ETDEWEB)

Johnson, J. D. (Prostat, Mesa, AZ); Oberkampf, William Louis; Helton, Jon Craig (Arizona State University, Tempe, AZ); Storlie, Curtis B. (North Carolina State University, Raleigh, NC)

2006-10-01

Evidence theory provides an alternative to probability theory for the representation of epistemic uncertainty in model predictions that derives from epistemic uncertainty in model inputs, where the descriptor epistemic is used to indicate uncertainty that derives from a lack of knowledge with respect to the appropriate values to use for various inputs to the model. The potential benefit, and hence appeal, of evidence theory is that it allows a less restrictive specification of uncertainty than is possible within the axiomatic structure on which probability theory is based. Unfortunately, the propagation of an evidence theory representation for uncertainty through a model is more computationally demanding than the propagation of a probabilistic representation for uncertainty, with this difficulty constituting a serious obstacle to the use of evidence theory in the representation of uncertainty in predictions obtained from computationally intensive models. This presentation describes and illustrates a sampling-based computational strategy for the representation of epistemic uncertainty in model predictions with evidence theory. Preliminary trials indicate that the presented strategy can be used to propagate uncertainty representations based on evidence theory in analysis situations where naive sampling-based (i.e., unsophisticated Monte Carlo) procedures are impracticable due to computational cost.

Monolith Chromatography as Sample Preparation Step in Virome Studies of Water Samples.

Science.gov (United States)

Gutiérrez-Aguirre, Ion; Kutnjak, Denis; Rački, Nejc; Rupar, Matevž; Ravnikar, Maja

2018-01-01

Viruses exist in aquatic media and many of them use this media as transmission route. Next-generation sequencing (NGS) technologies have opened new doors in virus research, allowing also to reveal a hidden diversity of viral species in aquatic environments. Not surprisingly, many of the newly discovered viruses are found in environmental fresh and marine waters. One of the problems in virome research can be the low amount of viral nucleic acids present in the sample in contrast to the background ones (host, eukaryotic, prokaryotic, environmental). Therefore, virus enrichment prior to NGS is necessary in many cases. In water samples, an added problem resides in the low concentration of viruses typically present in aquatic media. Different concentration strategies have been used to overcome such limitations. CIM monoliths are a new generation of chromatographic supports that due to their particular structural characteristics are very efficient in concentration and purification of viruses. In this chapter, we describe the use of CIM monolithic chromatography for sample preparation step in NGS studies targeting viruses in fresh or marine water. The step-by-step protocol will include a case study where CIM concentration was used to study the virome of a wastewater sample using NGS.

Episodic work-family conflict, cardiovascular indicators, and social support: an experience sampling approach.

Science.gov (United States)

Shockley, Kristen M; Allen, Tammy D

2013-07-01

Work-family conflict, a prevalent stressor in today's workforce, has been linked to several detrimental consequences for the individual, including physical health. The present study extends this area of research by examining episodic work-family conflict in relation to objectively measured cardiovascular health indicators (systolic and diastolic blood pressure and heart rate) using an experience sampling methodology. The results suggested that the occurrence of an episode of work interference with family conflict is linked to a subsequent increase in heart rate but not blood pressure; however, the relationship between episodes of family interference with work conflict and both systolic and diastolic blood pressure is moderated by perceptions of family-supportive supervision. No evidence was found for the moderating role of work-supportive family. Further theoretical and practical implications are discussed. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Efficiency enhancement of optimized Latin hypercube sampling strategies: Application to Monte Carlo uncertainty analysis and meta-modeling

Science.gov (United States)

Rajabi, Mohammad Mahdi; Ataie-Ashtiani, Behzad; Janssen, Hans

2015-02-01

The majority of literature regarding optimized Latin hypercube sampling (OLHS) is devoted to increasing the efficiency of these sampling strategies through the development of new algorithms based on the combination of innovative space-filling criteria and specialized optimization schemes. However, little attention has been given to the impact of the initial design that is fed into the optimization algorithm, on the efficiency of OLHS strategies. Previous studies, as well as codes developed for OLHS, have relied on one of the following two approaches for the selection of the initial design in OLHS: (1) the use of random points in the hypercube intervals (random LHS), and (2) the use of midpoints in the hypercube intervals (midpoint LHS). Both approaches have been extensively used, but no attempt has been previously made to compare the efficiency and robustness of their resulting sample designs. In this study we compare the two approaches and show that the space-filling characteristics of OLHS designs are sensitive to the initial design that is fed into the optimization algorithm. It is also illustrated that the space-filling characteristics of OLHS designs based on midpoint LHS are significantly better those based on random LHS. The two approaches are compared by incorporating their resulting sample designs in Monte Carlo simulation (MCS) for uncertainty propagation analysis, and then, by employing the sample designs in the selection of the training set for constructing non-intrusive polynomial chaos expansion (NIPCE) meta-models which subsequently replace the original full model in MCSs. The analysis is based on two case studies involving numerical simulation of density dependent flow and solute transport in porous media within the context of seawater intrusion in coastal aquifers. We show that the use of midpoint LHS as the initial design increases the efficiency and robustness of the resulting MCSs and NIPCE meta-models. The study also illustrates that this

Sampling strategies and materials for investigating large reactive particle complaints from Valley Village homeowners near a coal-fired power plant

International Nuclear Information System (INIS)

Chang, A.; Davis, H.; Frazar, B.; Haines, B.

1997-01-01

This paper will present Phase 3's sampling strategies, techniques, methods and substrates for assisting the District to resolve the complaints involving yellowish-brown staining and spotting of homes, cars, etc. These spots could not be easily washed off and some were permanent. The sampling strategies for the three phases were based on Phase 1 -- the identification of the reactive particles conducted in October, 1989 by APCD and IITRI, Phase 2 -- a study of the size distribution and concentration as a function of distance and direction of reactive particle deposition conducted by Radian and LG and E, and Phase 3 -- the determination of the frequency of soiling events over a full year's duration conducted in 1995 by APCD and IITRI. The sampling methods included two primary substrates -- ACE sheets and painted steel, and four secondary substrates -- mailbox, aluminum siding, painted wood panels and roof tiles. The secondary substrates were the main objects from the Valley Village complaints. The sampling technique included five Valley Village (VV) soiling/staining assessment sites and one southwest of the power plant as background/upwind site. The five VV sites northeast of the power plant covered 50 degrees span sector and 3/4 miles distance from the stacks. Hourly meteorological data for wind speeds and wind directions were collected. Based on this sampling technique, there were fifteen staining episodes detected. Nine of them were in summer, 1995

Generative Learning Strategy Use and Self-Regulatory Prompting in Digital Text

Science.gov (United States)

Reid, Alan J.; Morrison, Gary M.

2014-01-01

The digital revolution is shifting print-based textbooks to digital text, and it has afforded the opportunity to incorporate meaningful learning strategies and otherwise separate metacognitive activities directly into these texts as embedded support. A sample of 89 undergraduates read a digital, expository text on the basics of photography. The…

Strategies and Decision Support Systems for Integrating Variable Energy Resources in Control Centers for Reliable Grid Operations. Executive Summary

Energy Technology Data Exchange (ETDEWEB)

Jones, Lawrence E. [Alstom Grid, Inc., Washington, DC (United States)

2011-11-01

This is the executive summary for a report that provides findings from the field regarding the best ways in which to guide operational strategies, business processes and control room tools to support the integration of renewable energy into electrical grids.

A comparative study of care burden and social support among caregivers of persons with schizophrenia and epilepsy

Directory of Open Access Journals (Sweden)

Nilufer Karim

2015-07-01

Full Text Available Background: The caregivers of persons with epilepsy and schizophrenia undergo severe emotional, physical, financial burden due to the nature, chronicity, disability, and stigma attached to the illness. Aim: To assess the burden and social support among caregivers of persons with schizophrenia and epilepsy. Method: The study was conducted at the Out Patient Department of LokopriyaGopinathBordoloi Regional Institute of Mental Health, Tezpur. It was a comparative study. Purposive sampling technique was used for selection of the sample. The sample for the current study comprised of caregivers of 30 persons with schizophrenia and 30 persons suffering from epilepsy. A semi-structured socio-demographic data sheet, the Burden Assessment Schedule (BAS, the Social Support Questionnaire, and the General Health Questionnaire were administered to the caregivers. Results: There was no significant difference reported by the caregivers in the two groups with the entire domains of BAS and perceived social support. Physical and mental health, and caregivers’ strategy domains of BAS had significant negative correlation at 0.05 levels with perceived social support. External support, support of patient, taking responsibility, and other relation domains of BAS had significant negative correlation at the 0.01 level with perceived social support. Conclusion: While the two groups had no significant difference with the entire domains of BAS and perceived social support; physical and mental health, and caregivers’ strategy had significant negative correlation with perceived social support.

Upstream Disaster Management to Support People Experiencing Homelessness.

Science.gov (United States)

Sundareswaran, Madura; Ghazzawi, Andrea; O'Sullivan, Tracey L

2015-08-18

The unique context of day-to-day living for people who are chronically homeless or living with housing insecurity puts them at high risk during community disasters. The impacts of extreme events, such as flooding, storms, riots, and other sources of community disruption, underscore the importance of preparedness efforts and fostering community resilience. This study is part of larger initiative focused on enhancing resilience and preparedness among high risk populations. The purpose of this study was to explore critical issues and strategies to promote resilience and disaster preparedness among people who are homeless in Canada. A sample of interviews (n=21) from key informants across Canada was analyzed to explore existing programs and supports for homeless populations. The data was selected from a larger sample of (n=43) interviews focused on programs and supports for people who are at heightened risk for negative impacts during disasters. Qualitative content analysis was used to extract emergent themes and develop a model of multi-level collaboration to support disaster resilience among people who are homeless. The results indicate there is a need for more upstream continuity planning, collaboration and communication between the emergency management sector and community service organizations that support people who are homeless. Prioritization and investment in the social determinants of health and community supports is necessary to promote resilience among this high-risk population. The findings from this study highlight the importance of acknowledging community support organizations as assets in disaster preparedness. Day-to-day resilience is an ongoing theme for people who are chronically homeless or living with housing insecurity. Upstream investment to build adaptive capacity and collaborate with community organizations is an important strategy to enhance community resilience.

Contextual Exploration of a New Family Caregiver Support Concept for Geriatric Settings Using a Participatory Health Research Strategy.

Science.gov (United States)

Dorant, Elisabeth; Krieger, Theresia

2017-11-28

Family caregivers are the backbone of the long-term care support system within the home environment. Comprehensive caregiver support programs require collaboration and coordination within the system. A new public health concept, Vade Mecum, aims to harmonize and professionalize family caregiver support initiatives in geriatric care settings in the Euregion Maas-Rhine. Exploration of the new concept recently started in Germany to gain in-depth insight into current support and the needs of the geriatric care team and family caregivers. Within the context of an exploratory qualitative study, a participatory health research (PHR) strategy was applied to make optimal use of experience and knowledge from the system. Care professionals, engaged as co-researchers, were responsible for decisions about the research question, data collection methods and procedures of engaging family caregivers. A research team representing all professions within the geriatric department was formed. Research objectives were formulated and an appropriate mix of qualitative data collection methods consisting of interviews, focus groups and story-telling was chosen. Needs and expectations of the new concept, and practical solutions for involving family caregivers were discussed. A PHR strategy resulted in initiating a qualitative study in a geriatric care setting carried out by care professionals from the department. Knowledge was generated in a co-creative manner, and co-researchers were empowered. A comprehensive understanding of the system serves as a starting point for advancement of the new family caregiver concept.

Interactive Control System, Intended Strategy, Implemented Strategy dan Emergent Strategy

Directory of Open Access Journals (Sweden)

Tubagus Ismail

2012-09-01

Full Text Available The purpose of this study was to examine the relationship between management control system (MCS and strategy formation processes, namely: intended strategy, emergent strategy and impelemented strategy. The focus of MCS in this study was interactive control system. The study was based on Structural Equation Modeling (SEM as its multivariate analyses instrument. The samples were upper middle managers of manufacturing company in Banten Province, DKI Jakarta Province and West Java Province. AMOS Software 16 program is used as an additional instrument to resolve the problem in SEM modeling. The study found that interactive control system brought a positive and significant influence on Intended strategy; interactive control system brought a positive and significant influence on implemented strategy; interactive control system brought a positive and significant influence on emergent strategy. The limitation of this study is that our empirical model only used one way relationship between the process of strategy formation and interactive control system.

Sampling designs for contaminant temporal trend analyses using sedentary species exemplified by the snails Bellamya aeruginosa and Viviparus viviparus.

Science.gov (United States)

Yin, Ge; Danielsson, Sara; Dahlberg, Anna-Karin; Zhou, Yihui; Qiu, Yanling; Nyberg, Elisabeth; Bignert, Anders

2017-10-01

Environmental monitoring typically assumes samples and sampling activities to be representative of the population being studied. Given a limited budget, an appropriate sampling strategy is essential to support detecting temporal trends of contaminants. In the present study, based on real chemical analysis data on polybrominated diphenyl ethers in snails collected from five subsites in Tianmu Lake, computer simulation is performed to evaluate three sampling strategies by the estimation of required sample size, to reach a detection of an annual change of 5% with a statistical power of 80% and 90% with a significant level of 5%. The results showed that sampling from an arbitrarily selected sampling spot is the worst strategy, requiring much more individual analyses to achieve the above mentioned criteria compared with the other two approaches. A fixed sampling site requires the lowest sample size but may not be representative for the intended study object e.g. a lake and is also sensitive to changes of that particular sampling site. In contrast, sampling at multiple sites along the shore each year, and using pooled samples when the cost to collect and prepare individual specimens are much lower than the cost for chemical analysis, would be the most robust and cost efficient strategy in the long run. Using statistical power as criterion, the results demonstrated quantitatively the consequences of various sampling strategies, and could guide users with respect of required sample sizes depending on sampling design for long term monitoring programs. Copyright © 2017 Elsevier Ltd. All rights reserved.

A hybrid computational strategy to address WGS variant analysis in >5000 samples.

Science.gov (United States)

Huang, Zhuoyi; Rustagi, Navin; Veeraraghavan, Narayanan; Carroll, Andrew; Gibbs, Richard; Boerwinkle, Eric; Venkata, Manjunath Gorentla; Yu, Fuli

2016-09-10

The decreasing costs of sequencing are driving the need for cost effective and real time variant calling of whole genome sequencing data. The scale of these projects are far beyond the capacity of typical computing resources available with most research labs. Other infrastructures like the cloud AWS environment and supercomputers also have limitations due to which large scale joint variant calling becomes infeasible, and infrastructure specific variant calling strategies either fail to scale up to large datasets or abandon joint calling strategies. We present a high throughput framework including multiple variant callers for single nucleotide variant (SNV) calling, which leverages hybrid computing infrastructure consisting of cloud AWS, supercomputers and local high performance computing infrastructures. We present a novel binning approach for large scale joint variant calling and imputation which can scale up to over 10,000 samples while producing SNV callsets with high sensitivity and specificity. As a proof of principle, we present results of analysis on Cohorts for Heart And Aging Research in Genomic Epidemiology (CHARGE) WGS freeze 3 dataset in which joint calling, imputation and phasing of over 5300 whole genome samples was produced in under 6 weeks using four state-of-the-art callers. The callers used were SNPTools, GATK-HaplotypeCaller, GATK-UnifiedGenotyper and GotCloud. We used Amazon AWS, a 4000-core in-house cluster at Baylor College of Medicine, IBM power PC Blue BioU at Rice and Rhea at Oak Ridge National Laboratory (ORNL) for the computation. AWS was used for joint calling of 180 TB of BAM files, and ORNL and Rice supercomputers were used for the imputation and phasing step. All other steps were carried out on the local compute cluster. The entire operation used 5.2 million core hours and only transferred a total of 6 TB of data across the platforms. Even with increasing sizes of whole genome datasets, ensemble joint calling of SNVs for low

How Well Can Existing Software Support Processes Accomplish Sustainment of a Non-Developmental Item-Based Acquisition Strategy

Science.gov (United States)

2017-04-06

guidance to the PM regarding development and sustainment of software . The need for a strong application of software engineering principles is...on the battlefield by a government- developed network manager application . The configuration of this confluence of software will be jointly managed...How Well Can Existing Software -Support Processes Accomplish Sustainment of a Non- Developmental Item-Based Acquisition Strategy? Graciano

Area 3 Support Buildings (A3SB) H5-0992, H5-0996 PRL 218 Confirmatory Sampling Report

Science.gov (United States)

Mrdjenovich, Timothy

2015-01-01

The Area 3 Support Buildings site (A3SB) consists of two separate areas located on the north side of Beach Road in the northern portion of Kennedy Space Center, Florida (KSC), outside the secured perimeter of KSC. The A3SB areas are approximately 0.6 miles apart, and were developed as Shiffler's Grocery Store and Service Station (west site) and as a residence (east site) prior to acquisition by the National Aeronautics and Space Administration (NASA) in 1963. Both areas were used by the Bendix Company in support of NASA as chemical laboratories from 1963 through 1969. Both of the buildings were demolished by 1987. The west portion of the site was used by the US Fish & Wildlife Service (F&W) in support of the Merritt Island National Wildlife Refuge (MINWR) for parking at the entrance to the Hammock Trails from 1969 to the present. The east portion of the site was used for intermittent suspect materials staging in the early 1990s and is still used as an apiary location, but is otherwise no longer active. In support of the NASA HSWA permit requirements, this site was identified as Potential Release Location (PRL) 218 and a Solid Waste Management Unit (SWMU) Assessment (SA) was conducted in 2013. Confirmatory Sampling (CS) was recommended and approved by the KSC Remediation Team (KSCRT). Three locations of concern (LOCs) were identified and sampled at the site. The LOCs include two former chemical labs and a former suspect staging area. The CS was conducted in March of 2015 at three locations by means of Direct Push Technology (DPT) groundwater sampling and at one location for soil sampling. The samples were collected and analyzed in accordance with the approved CS Work Plan. There were no exceedances of criteria detected in any of the samples from the three LOCs. The results of this investigation indicate that past and/or present operations have not negatively impacted environmental media at the A3SB. Based upon no confirmed groundwater detections above GCTLs and no

Strategies to Support High School Students’ Reading Comprehension in the English Language

Directory of Open Access Journals (Sweden)

Zabala Palacio Freddy Oswaldo

2004-08-01

Full Text Available Teachers are often concerned about the low reading level of their students in both English and Spanish. One way to solve this problem is by using reading strategies. Promoting the development of reading competences in English will offer the students tools that allow them to comprehend texts and will contribute to a closer relation with the second language culture. This article reports on a study carried out when doing my teaching practice in a public high school in Bogotá, Colombia, in 2002. The main objective of my research project was to support the development of eleventh graders’ reading comprehension competence in English. Hence, I refer to the group’s views on English reading comprehension, their handling of strategies to develop reading competence in English and their progress after having applied those strategies. Key words: Foreign Language-Teaching, Reading Strategies El bajo nivel de lectura en los estudiantes de inglés y español es una de las preocupaciones comunes de los docentes. Una forma de solucionar este problema es a través del uso de estrategias de lectura. De tal manera, promover el desarrollo de competencias lectoras en los estudiantes de inglés les ofrecerá herramientas que les permitirán comprender los textos y contribuirá a crear una relación más cercana entre ellos y la cultura de la segunda lengua. Este artículo reporta un estudio llevado a cabo durante mi práctica docente en una escuela pública de Bogotá, Colombia, en el año 2002. El objetivo principal de mi proyecto de investigación fue apoyar el desarrollo de la competencia en comprensión de lectura en el idioma inglés en estudiantes de undécimo grado. Por lo tanto, menciono los puntos de vista de los estudiantes sobre la comprensión de lectura, la forma como utilizan las estrategias para desarrollar esta competencia en inglés y su proceso después de su acercamiento a la comprensión lectora a través del uso de las mismas

Evaluation of the Voltage Support Strategies for the Low Voltage Grid Connected PV

DEFF Research Database (Denmark)

Demirok, Erhan; Sera, Dezso; Teodorescu, Remus

2010-01-01

Admissible range of grid voltage is one of the strictest constraints for the penetration of distributed photovoltaic (PV) generators especially connection to low voltage (LV) public networks. Voltage limits are usually fulfilled either by network reinforcements or limiting of power injections from...... PVs. In order to increase PV penetration level further, new voltage support control functions for individual inverters are required. This paper investigates distributed reactive power regulation and active power curtailment strategies regarding the development of PV connection capacity by evaluation...... of reactive power efforts and requirement of minimum active power curtailment. Furthermore, a small scale experimental setup is built to reflect real grid interaction in the laboratory by achieving critical types of grid (weak and sufficiently stiff)....

Decision support model for establishing the optimal energy retrofit strategy for existing multi-family housing complexes

International Nuclear Information System (INIS)

Hong, Taehoon; Koo, Choongwan; Kim, Hyunjoong; Seon Park, Hyo

2014-01-01

The number of multi-family housing complexes (MFHCs) over 15 yr old in South Korea is expected to exceed 5 million by 2015. Accordingly, the demand for energy retrofit in the deteriorating MFHCs is rapidly increasing. This study aimed to develop a decision support model for establishing the optimal energy retrofit strategy for existing MFHCs. It can provide clear criteria for establishing the carbon emissions reduction target (CERT) and allow efficient budget allocation for conducting the energy retrofit. The CERT for “S” MFHC, one of MFHCs located in Seoul, as a case study, was set at 23.0% (electricity) and 27.9% (gas energy). In the economic and environmental assessment, it was determined that scenario #12 was the optimal scenario (ranked second with regard to NPV 40 (net present value at year 40) and third with regard to SIR 40 (saving to investment ratio at year 40). The proposed model could be useful for owners, construction managers, or policymakers in charge of establishing energy retrofit strategy for existing MFHCs. It could allow contractors in a competitive bidding process to rationally establish the CERT and select the optimal energy retrofit strategy. It can be also applied to any other country or sector in a global environment. - Highlights: • The proposed model was developed to establish the optimal energy retrofit strategy. • Advanced case-based reasoning was applied to establish the community-based CERT. • Energy simulation was conducted to analyze the effects of energy retrofit strategy. • The optimal strategy can be finally selected based on the LCC and LCCO 2 analysis. • It could be extended to any other country or sector in the global environment

Bias of shear wave elasticity measurements in thin layer samples and a simple correction strategy.

Science.gov (United States)

Mo, Jianqiang; Xu, Hao; Qiang, Bo; Giambini, Hugo; Kinnick, Randall; An, Kai-Nan; Chen, Shigao; Luo, Zongping

2016-01-01

Shear wave elastography (SWE) is an emerging technique for measuring biological tissue stiffness. However, the application of SWE in thin layer tissues is limited by bias due to the influence of geometry on measured shear wave speed. In this study, we investigated the bias of Young's modulus measured by SWE in thin layer gelatin-agar phantoms, and compared the result with finite element method and Lamb wave model simulation. The result indicated that the Young's modulus measured by SWE decreased continuously when the sample thickness decreased, and this effect was more significant for smaller thickness. We proposed a new empirical formula which can conveniently correct the bias without the need of using complicated mathematical modeling. In summary, we confirmed the nonlinear relation between thickness and Young's modulus measured by SWE in thin layer samples, and offered a simple and practical correction strategy which is convenient for clinicians to use.

Dignity and Deferral Narratives as Strategies in Facilitated Technology-Based Support Groups for People with Advanced Cancer

Directory of Open Access Journals (Sweden)

Annette F. Street

2012-01-01

Full Text Available This paper examines the value of facilitated telephone and online support groups for palliative care. Telephone interviews were conducted with twenty people living with advanced cancer who had participated in either a telephone or online support group facilitated by the Cancer Council Victoria, Melbourne, Australia. Two dominant participant narratives emerged: a focus on dying with dignity or an interest in deferring discussion of death and dying to focus on the present. Despite the different approaches, participants found the technology-based support groups to be accessible and safe environments in which to discuss difficult topics in privacy. Technology-based strategies provide opportunities for health professionals to provide social and emotional care to more people by moving beyond individualised care and facilitate peer-to-peer support at the end of life, especially to those with specific needs. Such options are feasible for palliative care services to set up and acceptable to a group of clients, especially for younger clients or those socially or geographically isolated.

Testing a Model of Functional Impairment in Telephone Crisis Support Workers.

Science.gov (United States)

Kitchingman, Taneile A; Wilson, Coralie J; Caputi, Peter; Wilson, Ian; Woodward, Alan

2017-11-01

It is well known that helping professionals experience functional impairment related to elevated symptoms of psychological distress as a result of frequent empathic engagement with distressed others. Whether telephone crisis support workers are impacted in a similar way is not currently reported in the literature. The purpose of this study was to test a hypothesized model of factors contributing to functional impairment in telephone crisis support workers. A national sample of 210 telephone crisis support workers completed an online survey including measures of emotion regulation, symptoms of general psychological distress and suicidal ideation, intentions to seek help for symptoms, and functional impairment. Structural equation modeling was used to test the fit of the data to the hypothesized model. Goodness-of-fit indices were adequate and supported the interactive effects of emotion regulation, general psychological distress, suicidal ideation, and intentions to seek help for ideation on functional impairment. These results warrant the deliberate management of telephone crisis support workers' impairment through service selection, training, supervision, and professional development strategies. Future research replicating and extending this model will further inform the modification and/or development of strategies to optimize telephone crisis support workers' well-being and delivery of support to callers.