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Sample records for samel jri siigur

  1. PENGARUH PARTISIPASI ANGGARAN TERHADAP KINERJA MANAJERIAL DENGAN JOB RELEVANT INFORMATION (JRI) DAN KOMITMEN ORGANISASI SEBAGAI VARIABEL INTERVENING (Survei Pada Perusahaan Perbankan di Kota Jambi)

    OpenAIRE

    Prasetio, Primadi

    2016-01-01

    ABSTRACT For reaching the target for the increase of managerial performance to consider factors that can influence the issue, among others, the participation of the budget. Participation budget can not walk alone in influencing managerial performance, but there are other factors that synergize, including organizational commitment and job relevant information (JRI). Researchs on the factors that influence managerial performance such as participation of the budget, organizational commitment and...

  2. A Study on the Joint Reliability Importance with Applications to the Maintenance Policy

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jung Sik; Kwon, Hong Je; Song, Mi Ja; Kim, Woong Kil; Yoong, Do Hwa [Seoul National Polytechnic University, Seoul (Korea, Republic of); Moon, Sin Myung; Cho, Bong Je; Moon, Jae Phil; Koo, Hoon Young; Lee, Jin Seung [Seoul National University, Seoul (Korea, Republic of)

    1997-09-01

    The objective of this project is to investigate the possibility of applying the Joint Reliability Importance(JRI) of two components to the establishment of system maintenance policy. Components are classified into reliability substitutes and reliability compliments. If the sign of JRI of two components is positive, they are called as reliability compliments. If the sign of JRI of two components is negative, they are called as reliability substitutes. In case of reliability compliments, one component becomes more important as the other one works and in case of reliability substitutes, one component becomes more important as the other one fails. Therefore, when the preventive maintenance is carried out, two components which are reliability substitutes should not be maintained at the same time. Also, when the corrective maintenance is carried out, we not only repair the failed components but pay attention to the functioning components which are reliability substitutes with respect to the failed components. The sign of JRI of any two components in series (parallel) system is positive (negative). Then, what is the sign of any two components in k-out-of-n:G system? This project presents an idea of characterizing the k-out-of-n:G system by calculating the JRI of two components in that system, assuming that reliability of all components are equal. In addition to the JRI of two components, JRI of two gates is introduced in this project. The algorithm to compute the JRI of two gates is presented. Bridge system is considered and the co-relation of two min cut sets is illustrated by using the cut-set representation of bridge system and calculating the JRI of two gates. 28 refs., 20 tabs., 32 figs. (author)

  3. Demonstration of Laser Plasma X-Ray Source with X-Ray Collimator Final Report CRADA No. TC-1564-99

    Energy Technology Data Exchange (ETDEWEB)

    Lane, S. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Forber, R. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-09-28

    This collaborative effort between the University of California, Lawrence Livermore National Laboratory (LLNL) and JMAR Research, Inc. (JRI), was to demonstrate that LLNL x-ray collimators can effectively increase the wafer throughput of JRI's laser based x-ray lithography systems. The technical objectives were expected to be achieved by completion of the following tasks, which are separated into two task lists by funding source. The organization (LLNL or JMAR) having primary responsibility is given parenthetically for each task.

  4. The Sustainable University: Green Goals and New Challenges for Higher Education Leaders

    Science.gov (United States)

    Martin, James; Samels, James E.

    2012-01-01

    Colleges and universities are at the forefront of efforts to preserve the earth's resources for future generations. Carbon neutrality, renewable energy sources, green building strategies, and related initiatives require informed and courageous leaders at all levels of higher education. James Martin and James E. Samels have worked closely with…

  5. Toward improved construction health, safety, and ergonomics in ...

    African Journals Online (AJOL)

    Hierdie dien as plaaslike insig en 'n lyn van gestruktureerde vrae vir gebruik in die hoofstudie, wat geposisioneer is in die aksie-navorsing (AN) paradigma en gebruik die fokusgroep (FG) metode om groot kwalitatiewe data in te samel van SARAP-geregistreerde deelnemers. Sintese van die FG data met die literatuur asook ...

  6. Die skool en die onderwyser as faktore in die geestesgesondheid van die kind*

    Directory of Open Access Journals (Sweden)

    B. C. Schutte

    1961-03-01

    Full Text Available Ons hou geestesgesondheidsweke, stig beroepsentrums, samel geld in om mense wat geestelik siek is te genees, klae oor die tekort aan psigiaters, kliniese sielkundiges, bedryfsielkundiges, voorligters, skoolpsigoloë,ens. ’n Karige kwarteeu gelede het ons aan al hierdie dinge slegs akademiese aandag gewy. In hierdie kursus wordverskeie tipes kinders bespreek en geleer hoe om hulle probleme te benader.

  7. Electronic Publishing Approaches to Curriculum: Videotex, Teletext and Databases.

    Science.gov (United States)

    Aumente, Jerome

    1986-01-01

    Describes the Journalism Resources Institute (JRI) of Rutgers University in terms of its administrative organization, computer resources, computer facilities use, involvement in electronic publishing, use of the Dow Jones News/Retrieval Database, curricular options, and professional continuing education. (AYC)

  8. Seasonal Water Transport in the Atmosphere of Mars: Applications of a Mars General Circulation Model Using Mars Global Surveyor Data

    Science.gov (United States)

    Hollingsworth, Jeffery L.; Bridger, Alison F. C.; Haberle, Robert M.

    1999-01-01

    This is a Final Report for a Joint Research Interchange (JRI) between NASA Ames Research Center and San Jose State University, Department of Meteorology. We present below a summary of progress made during the duration of this JRI. The focus of this JRI has been to investigate seasonal water vapor transport in the atmosphere of Mars and its effects on the planet's present climate. To this end, the primary task has been to adapt a new dynamical processor for the adiabatic tendencies of the atmospheric circulation into the NASA Ames Mars general circulation model (MGCM). Using identical boundary and initial conditions, several comparative tests between the new and old MGCMs have been performed and the nature of the simulated circulations have been diagnosed. With confidence that the updated version of the Ames MGCM produces quite similar mean and eddy circulation statistics, the new climate model is well poised as a tool to pursue fundamental questions related to the spatial and seasonal variations of atmospheric water vapor on Mars, and to explore exchanges of water with non-atmospheric reservoirs and transport within its atmosphere. In particular, the role of surface sources and sinks can be explored, the range of water-vapor saturation altitudes can be investigated, and plausible precipitation mechanisms can be studied, for a range of atmospheric dust loadings. Such future investigations can contribute to a comprehensive study of surface inventories, exchange mechanisms, and the relative importance of atmospheric transport Mars' water cycle. A listing of presentations made and manuscripts submitted during the course of this project is provided.

  9. Transactions of the Conference of Army Mathematicians (26th) Held at Hanover, New Hampshire on 10 - 12 June 1980.

    Science.gov (United States)

    1981-01-01

    swee r the Mlor-Le ’a ie tayl e to li thin thle acca - rae. i tti h n IIrfleI-ieCaL I dit a . Iceo inl t ii hreJries o. however, the iorteot the( pA1...bifurcations, which surprised us, the perturbed problem has solutions which may be approximated by the scheme proposed in fFM ]. In a way, the asser- tion

  10. Eesti tööseaduste täiustamisest / Heino Siigur

    Index Scriptorium Estoniae

    Siigur, Heino, 1930-

    2007-01-01

    Töölepingu lõpetamisest ja hüvitiste maksmisest vallandamise, konkurentsikeelu järgimise ning äri- ja tootmissaladuse hoidmise eest. Tööandja distsiplinaarvõimust, töötaja distsiplinaarvastutusest ja palgasaladuse mõistest

  11. [Lugejad küsivad - meie autorid vastavad] / Heino Siigur, Darja Roos, Jelizaveta Litau...[ jt.

    Index Scriptorium Estoniae

    2010-01-01

    Ületunnitöö arvestusest, kapitali konventeerimisest ja ümberarvestamisest eurodeks, sotsiaalmaksu miinimumi maksmisest, elatise arvestamisest, teenuse osutamisest madala maksumääraga territooriumil, töötasu arvutamise viisidest

  12. Glacial–interglacial dynamics of Antarctic firn columns: comparison between simulations and ice core air-δ15N measurements

    Directory of Open Access Journals (Sweden)

    E. Capron

    2013-05-01

    Full Text Available Correct estimation of the firn lock-in depth is essential for correctly linking gas and ice chronologies in ice core studies. Here, two approaches to constrain the firn depth evolution in Antarctica are presented over the last deglaciation: outputs of a firn densification model, and measurements of δ15N of N2 in air trapped in ice core, assuming that δ15N is only affected by gravitational fractionation in the firn column. Since the firn densification process is largely governed by surface temperature and accumulation rate, we have investigated four ice cores drilled in coastal (Berkner Island, BI, and James Ross Island, JRI and semi-coastal (TALDICE and EPICA Dronning Maud Land, EDML Antarctic regions. Combined with available ice core air-δ15N measurements from the EPICA Dome C (EDC site, the studied regions encompass a large range of surface accumulation rates and temperature conditions. Our δ15N profiles reveal a heterogeneous response of the firn structure to glacial–interglacial climatic changes. While firn densification simulations correctly predict TALDICE δ15N variations, they systematically fail to capture the large millennial-scale δ15N variations measured at BI and the δ15N glacial levels measured at JRI and EDML – a mismatch previously reported for central East Antarctic ice cores. New constraints of the EDML gas–ice depth offset during the Laschamp event (~41 ka and the last deglaciation do not favour the hypothesis of a large convective zone within the firn as the explanation of the glacial firn model–δ15N data mismatch for this site. While we could not conduct an in-depth study of the influence of impurities in snow for firnification from the existing datasets, our detailed comparison between the δ15N profiles and firn model simulations under different temperature and accumulation rate scenarios suggests that the role of accumulation rate may have been underestimated in the current description of firnification

  13. Gurmaanlus ruulib / Marika Makarova ; kommenteerinud Anu Tali, René Uusmees, Tõnis Siigur, Hannes Võrno, Dimitri Demjanov

    Index Scriptorium Estoniae

    Makarova, Marika

    2010-01-01

    Tulevikutoidu konverentsil Tallinnas esinenud kuulsate kokkade Albert Adria, Fergus Hendersoni ja Claus Meyeri kokakunsti lähtekohtadest ja mõistet gurmaanlus mõtestavad lahti tuntud Eesti inimesed ja kokad

  14. Development of JSTAMP-Works/NV and HYSTAMP for Multipurpose Multistage Sheet Metal Forming Simulation

    Science.gov (United States)

    Umezu, Yasuyoshi; Watanabe, Yuko; Ma, Ninshu

    2005-08-01

    Since 1996, Japan Research Institute Limited (JRI) has been providing a sheet metal forming simulation system called JSTAMP-Works packaged the FEM solvers of LS-DYNA and JOH/NIKE, which might be the first multistage system at that time and has been enjoying good reputation among users in Japan. To match the recent needs, "faster, more accurate and easier", of process designers and CAE engineers, a new metal forming simulation system JSTAMP-Works/NV is developed. The JSTAMP-Works/NV packaged the automatic healing function of CAD and had much more new capabilities such as prediction of 3D trimming lines for flanging or hemming, remote control of solver execution for multi-stage forming processes and shape evaluation between FEM and CAD. On the other way, a multi-stage multi-purpose inverse FEM solver HYSTAMP is developed and will be soon put into market, which is approved to be very fast, quite accurate and robust. Lastly, authors will give some application examples of user defined ductile damage subroutine in LS-DYNA for the estimation of material failure and springback in metal forming simulation.

  15. Development of JSTAMP-Works/NV and HYSTAMP for Multipurpose Multistage Sheet Metal Forming Simulation

    International Nuclear Information System (INIS)

    Umezu, Yasuyoshi; Watanabe, Yuko; Ma, Ninshu

    2005-01-01

    Since 1996, Japan Research Institute Limited (JRI) has been providing a sheet metal forming simulation system called JSTAMP-Works packaged the FEM solvers of LS-DYNA and JOH/NIKE, which might be the first multistage system at that time and has been enjoying good reputation among users in Japan. To match the recent needs, 'faster, more accurate and easier', of process designers and CAE engineers, a new metal forming simulation system JSTAMP-Works/NV is developed. The JSTAMP-Works/NV packaged the automatic healing function of CAD and had much more new capabilities such as prediction of 3D trimming lines for flanging or hemming, remote control of solver execution for multi-stage forming processes and shape evaluation between FEM and CAD.On the other way, a multi-stage multi-purpose inverse FEM solver HYSTAMP is developed and will be soon put into market, which is approved to be very fast, quite accurate and robust.Lastly, authors will give some application examples of user defined ductile damage subroutine in LS-DYNA for the estimation of material failure and springback in metal forming simulation

  16. Child and youth care workers: Profile, nutrition knowledge and food safety and hygiene practices

    Directory of Open Access Journals (Sweden)

    Hendrina H. Grobbelaar

    2014-08-01

    Doelwit: Die doel van hierdie beskrywende kwantitatiewe studie was om die profiel, voeding kennis en voedsel- veiligheid en higiëne van kinder-en jeugsorgwerkers te ondersoek in residensiële sorg instellings met die doel om ’n voedsel voorbereiding en voedings handleiding te ontwikkel. Metode: Die residensiële sorg instellings het bestaan uit drie ewekansig gekiesde kinderhuise in Durban. Die studie het bestaan uit kinder-en jeugsorgwerkers (N = 40 in permanente of deeltydse poste. ’n Doelgerigte steekproef van die kinder-en jeugsorgwerkers is onderneem. ’n Gestruktureerde self-geadministreerde vraelys, ontwikkel en getoets vir hierdie doel, is gebruik om inligting oor die profiel, voeding kennis, voedselveiligheid en higiëniese praktyke van die kinder- en jeugsorgwerkers in te samel. Die data is ontleed vir beskrywende statistieke. Resultate: Die meerderheid van die kinder- en jeugsorgwerkers was vroulik, tussen die ouderdomme van 18−34 jaar. Min het ‘n toepaslike tersiêre kwalifikasie gehad. Dit blyk uit die resultate dat die respondente se algemene voeding riglyne was aanvaarbaar. Die resultate het gedui op ’n gebrek aan kennis oor die aanbevole vrugte en groente inname, korrekte porsiegroottes en die belangrikheid van ’n verskeidenheid in die dieet. Die respondente het tot ’n mindere mate kennis oor voedselveiligheid en higiëne gehad. Gevolgtrekking: Die algemene bevindinge ondersteun die ontwikkeling van ’n omvattende voedsel voorbereiding en voedings handleiding vir kinder residensiële sorg instellings.

  17. Guided reflection as a tool to deal with the theory– practice gap in critical care nursing students

    Directory of Open Access Journals (Sweden)

    Hester Cathrina de Swardt

    2012-04-01

    Opsomming Kritiekesorgverpleegstudente ervaar teenstrydighede ten opsigte van dit wat hul geleer word en wat van hul in die praktyk verwag word wat weer die leerproses vertraag. Dit word as die teorie–praktykgaping beskryf. Daar blyk geen enkelvoudige oplossing te wees vir die integrasie van teorie en praktyk nie. In ’n poging om die gaping te oorbrug, is ’n studie oor die invloed van begeleide refleksie op kritiekesorgverpleegkundige studente se teoretiese en praktiese ervaringe gedoen. ’n Kwalitatiewe, verkennende, beskrywende en kontekstuele navorsingsontwerp is gevolg. ‘n Instrument vir begeleide refleksie is ontwerp wat gebruik is tydens semi-gestruktureerde onderhoude in die data-insamelingsproses. Veldnotas en narratiewe beskrywings was ook middele ten einde data in te samel. Tema’s wat uit die data na vore gekom het was ‘n beskrywing van ervaringe, kritiese analise van data, kritiese analise van gevoelens en ‘n veranderde perspektief met betrekking tot ervaringe. Teorie–praktyk integrasie het tot ‘n mate in sommige kategorieë plaasgevind het. Daarinteen het die onvermoë om die teorie in die praktyk toe te pas response tot gevolg gehad, soos skuldgevoelens en gevoelens van onbevoegdheid. Dit wil voorkom asof begeleide refleksie die deelnemers gehelp het om duidelikheid en ’n veranderde perspektief ten opsigte van hul teoretiese en praktiese ervaringe te verkry. Begeleide refleksie behoort reeds vanaf basiese opleiding in verpleegkundiges se teoretiese en praktiese opleiding geïnkorporeer te word sodat verpleegkundiges bewus sal wees van hulle eie vaardighede om sodoende optimale pasiëntsorg te kan lewer.

  18. The health care needs of the physically disabled patient in a home-based care environment: Implications for the training of ancillary health care workers

    Directory of Open Access Journals (Sweden)

    Karien Jooste

    2010-11-01

    Opsomming Volgens die literatuur kan assistentgesondheidsorgwerkers (AGWs, as gevolg van ontoereikende opleiding, nie altyd aan die behoeftes van fisies gestremde pasiënte in 'n tuisopset voldoen nie.Die doel van hierdie navorsingstudie was om die gesondheidsorgbehoeftes van langtermyn,tuisgebaseerde fisies gestremde pasiënte in die noordelike voorstede van Johannesburg te verken en te beskryf, en om hieruit aanbevelings vir die opleiding van AGWs voor te stel. Kwalitatiewe,verkennende, beskrywende en kontekstuele metodes is gebruik om die data in te samel en die analise te doen. Die studiepopulasie het uit agt fisies gestremde deelnemers bestaan wat 'n AGW aangestel het om hulle met hul langtermyntuisversorging by te staan. Doelbewuste steekproefneming met die daaropvolgendesneeubalmetode is gebruik om verdere deelnemers vir die studie te identifiseer.Individuele onderhoude is gevoer waartydens deelnemers die volgende vrae moes beantwoord (1‘Wat is jou gesondheidsorgbehoeftes?’ en (2 ‘Hoe behoort hieraan voldoen te word?’ Datasaturasie is verseker, waarna Tesch se data-analisemetode gevolg is. Drie kategorieë van gesondheidsorgbehoeftes is geïdentifiseer (1 fisiese gesondheidsorgbehoeftes, (2 interpersoonlike verhoudingsbehoeftes en (3sosiale behoeftes, en 12 temas is van hierdie kategorieë afgelei. Hierdie gesondheidsorgkategorieë behoort aandag tydens die opleiding van AGWs te kry. Aan die hand van die temas is aanbevelings gemaak vir die opleiding van AGWs in tuisgebaseerde sorg van fisies gestremde pasiënte. AGWs behoort ondersteuning te bied om die omgewing by die individuele behoeftes van die pasiënt aan te pas, en moet hul kennis en kritiese denkvaardighede kan toepas om ʼn pasiëntgesentreerde omgewing te verseker.

  19. Tööandja huvide ja õiguste kaitse töösuhetes : [bakalaureusetöö] / Marek Piiroja ; Tartu Ülikooli Õigusinstituut ; juhendaja: Heino Siigur

    Index Scriptorium Estoniae

    Piiroja, Marek

    2005-01-01

    Tööandja õiguslik staatus EV-s 1918-1939, taasiseseisvunud Eesti tööõigusest tulenevad tööandja huvide ja õiguste kaitse, sellega seonduvad probleemid, Eesti tööandjate huvide ja õiguste kaitse erinevusi võrreldes Prantsusmaa tööõiguse ja EL direktiividega

  20. Patient-perceived factors contributing to low tuberculosis cure rate at Greater Giyani healthcare facilities

    Directory of Open Access Journals (Sweden)

    Nandzumuni V. Maswanganyi

    2014-04-01

    Doelwitte: Die doel van die studie was om die faktore wat in die Groter Giyani Munisipaliteit tot lae genesingskoerse onder TB-pasiënte lei, te ondersoek en te beskryf, soos deur pasiënte gesien. Metode: Die studie is in die Groter Giyani Munisipaliteit in die Limpopo Provinsie gehou, waar die genesingskoers vir TB tussen 14% en 94% is. Die navorsing in hierdie studie was kwalitatief, verkennend, beskrywend en kontekstueel van aard. Die populasie het bestaan uit alle gediagnoseerde TB-pasiënte wat vir behandeling en sorg na primêre gesondheidsorgfasiliteite verwys is. Nie-waarskynlikheid, doelgerigte steekproefneming is gebruik om TB-pasiënte en gesondheidsfasiliteite te kies wat ’n laer genesingskoers as die nasionale doelwit van 85% het. Een pasiënt uit elke primêre gesondheidsorgfasiliteit is by die steekproef ingesluit. ‘n Diepgaande persoonlike onderhoud is gebruik om data met behulp van ‘n onderhoudgids in te samel. Resultate: Die bevindinge toon dat die meeste van die TB-pasiënte uit arm gesinne kom, wat dit vir hulle moeilik maak om finansiële en voedselsekerheid te hê. Die gesondheidsfasiliteite se voedselaanvullings en TB-medisyne raak dikwels op. Kulturele oortuigings oor TB lei ook daartoe dat TB-pasiënte by tradisionele gesondheidsorgpraktisyns en geloofsgebaseerde genesers hulp soek. Gevolgtrekking: Dit is nodig dat ‘n beleid oor toesig oor die behandeling van ontslaande TB-pasiënte wat tuis aansterk, opgestel word. Gesondheidsorgfasiliteite behoort ook seker te maak dat daar genoeg medisyne vir hierdie pasiënte is, aangesien ‘n gebrek aan medisyne daartoe kan lei dat die pasiënte ophou om hulle medikasie te gebruik.

  1. Micro-Pressure Sensors for Future Mars Missions

    Science.gov (United States)

    Catling, David C.

    1996-01-01

    The joint research interchange effort was directed at the following principal areas: u further development of NASA-Ames' Mars Micro-meteorology mission concept as a viable NASA space mission especially with regard to the science and instrument specifications u interaction with the flight team from NASA's New Millennium 'Deep-Space 2' (DS-2) mission with regard to selection and design of micro-pressure sensors for Mars u further development of micro-pressure sensors suitable for Mars The research work undertaken in the course of the Joint Research Interchange should be placed in the context of an ongoing planetary exploration objective to characterize the climate system on Mars. In particular, a network of small probes globally-distributed on the surface of the planet has often been cited as the only way to address this particular science goal. A team from NASA Ames has proposed such a mission called the Micrometeorology mission, or 'Micro-met' for short. Surface pressure data are all that are required, in principle, to calculate the Martian atmospheric circulation, provided that simultaneous orbital measurements of the atmosphere are also obtained. Consequently, in the proposed Micro-met mission a large number of landers would measure barometric pressure at various locations around Mars, each equipped with a micro-pressure sensor. Much of the time on the JRI was therefore spent working with the engineers and scientists concerned with Micro-met to develop this particular mission concept into a more realistic proposition.

  2. A Catalase-related Hemoprotein in Coral Is Specialized for Synthesis of Short-chain Aldehydes: DISCOVERY OF P450-TYPE HYDROPEROXIDE LYASE ACTIVITY IN A CATALASE.

    Science.gov (United States)

    Teder, Tarvi; Lõhelaid, Helike; Boeglin, William E; Calcutt, Wade M; Brash, Alan R; Samel, Nigulas

    2015-08-07

    In corals a catalase-lipoxygenase fusion protein transforms arachidonic acid to the allene oxide 8R,9-epoxy-5,9,11,14-eicosatetraenoic acid from which arise cyclopentenones such as the prostanoid-related clavulones. Recently we cloned two catalase-lipoxygenase fusion protein genes (a and b) from the coral Capnella imbricata, form a being an allene oxide synthase and form b giving uncharacterized polar products (Lõhelaid, H., Teder, T., Tõldsepp, K., Ekins, M., and Samel, N. (2014) PloS ONE 9, e89215). Here, using HPLC-UV, LC-MS, and NMR methods, we identify a novel activity of fusion protein b, establishing its role in cleaving the lipoxygenase product 8R-hydroperoxy-eicosatetraenoic acid into the short-chain aldehydes (5Z)-8-oxo-octenoic acid and (3Z,6Z)-dodecadienal; these primary products readily isomerize in an aqueous medium to the corresponding 6E- and 2E,6Z derivatives. This type of enzymatic cleavage, splitting the carbon chain within the conjugated diene of the hydroperoxide substrate, is known only in plant cytochrome P450 hydroperoxide lyases. In mechanistic studies using (18)O-labeled substrate and incubations in H2(18)O, we established synthesis of the C8-oxo acid and C12 aldehyde with the retention of the hydroperoxy oxygens, consistent with synthesis of a short-lived hemiacetal intermediate that breaks down spontaneously into the two aldehydes. Taken together with our initial studies indicating differing gene regulation of the allene oxide synthase and the newly identified catalase-related hydroperoxide lyase and given the role of aldehydes in plant defense, this work uncovers a potential pathway in coral stress signaling and a novel enzymatic activity in the animal kingdom. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. A Catalase-related Hemoprotein in Coral Is Specialized for Synthesis of Short-chain Aldehydes

    Science.gov (United States)

    Teder, Tarvi; Lõhelaid, Helike; Boeglin, William E.; Calcutt, Wade M.; Brash, Alan R.; Samel, Nigulas

    2015-01-01

    In corals a catalase-lipoxygenase fusion protein transforms arachidonic acid to the allene oxide 8R,9-epoxy-5,9,11,14-eicosatetraenoic acid from which arise cyclopentenones such as the prostanoid-related clavulones. Recently we cloned two catalase-lipoxygenase fusion protein genes (a and b) from the coral Capnella imbricata, form a being an allene oxide synthase and form b giving uncharacterized polar products (Lõhelaid, H., Teder, T., Tõldsepp, K., Ekins, M., and Samel, N. (2014) PloS ONE 9, e89215). Here, using HPLC-UV, LC-MS, and NMR methods, we identify a novel activity of fusion protein b, establishing its role in cleaving the lipoxygenase product 8R-hydroperoxy-eicosatetraenoic acid into the short-chain aldehydes (5Z)-8-oxo-octenoic acid and (3Z,6Z)-dodecadienal; these primary products readily isomerize in an aqueous medium to the corresponding 6E- and 2E,6Z derivatives. This type of enzymatic cleavage, splitting the carbon chain within the conjugated diene of the hydroperoxide substrate, is known only in plant cytochrome P450 hydroperoxide lyases. In mechanistic studies using 18O-labeled substrate and incubations in H218O, we established synthesis of the C8-oxo acid and C12 aldehyde with the retention of the hydroperoxy oxygens, consistent with synthesis of a short-lived hemiacetal intermediate that breaks down spontaneously into the two aldehydes. Taken together with our initial studies indicating differing gene regulation of the allene oxide synthase and the newly identified catalase-related hydroperoxide lyase and given the role of aldehydes in plant defense, this work uncovers a potential pathway in coral stress signaling and a novel enzymatic activity in the animal kingdom. PMID:26100625

  4. An estimate of seasonality and intensity of infection with gastrointestinal nematodes in sheep and goats . in West Java

    Directory of Open Access Journals (Sweden)

    Beriajaya

    1998-12-01

    Full Text Available Tracer Inoodle tbin-tail sheep and Kacang goats were used to measure the seasonal changes in gastrointestinal nematodes parasitism i ~'und[, .xillapek .Fodd~ 'ofis in West Java . Each 3 months for 12 months worm-free male sheep (5 and goats (5 about 5 months of age were ~ $Jri~tgldI o% ef- farmer, and managed as part of their flock for 2 months . Animals were then returned to the laboratory and maintained on "`~^taaan-ftwAiet in elevated slatted pens for 3 weeks prior to slaughter. In all trials sheep had higher faecal egg counts than goats . Egg counts were significantly lower during the late dry-early wet season due mainly to lower burdens of Oesophagostomum spp. than at other times of the year. The predominant genera recovered from faecal larval cultures were Haemonchus and Trichostrongylus . At post mortem more than 94 percent of animals were infected with Trichostrongylus colubriformis, T. axei, Haemonchus contortus, Oesophagostomum columbianwn and Strongyloides papillosus . Other species found, in descending order of occurrence, were Cooperia curticei, Trichuris ovis, Bunostornum trigonocephalum, Oesophagostomumn asperum, Capillaria bovis and Gaigena pachycelis. It was concluded that intensity of exposure of both sheep and goats to H contortus, T. axei and C. curticei was similar throughout the year, but that availability of infectioe larvae of T. colubriformis was higher during the dry than the wet season and vise versa for O. columbianum . Sheep had higher burdens of T. Colubrzformis than goats but similar numbers of other species.

  5. Career And Life-Balance Of Professional Women: A South African Study

    Directory of Open Access Journals (Sweden)

    Thana Whitehead

    2003-11-01

    Full Text Available A woman’s ability to balance multiple life-roles is directly related to her physical and mental well-being, and her career performance and success. This study aims to infer a theoretical framework for the in-depth understanding of the phenomenon of life-balance in the lives of 24 South African professional women. The Grounded Theory as a qualitative method was applied to derive a theory about the phenomenon inductively. Purposeful sampling was used to identify 24 professional women. In-depth interviews and a group session were conducted to gather data, and to confirm themes and concepts on which the theoretical framework was based. It was concluded that life-balance is a life-process with a cyclical nature, and a useful tool for achieving personal growth. Life-balance is therefore not “one, single ultimate experience", but a series of individual experiences unfolding over time, which could be better described as “life-balance moments". Opsomming ‘n Vrou se vermoë om meervoudige lewensrolle te balanseer is direk verwant aan haar fisiese en geesteswelsyn en ook haar loopbaanprestasie en -sukses. Hierdie studie het ten doel om ‘n teoretiese raamwerk af te lei uit die indiepte begrip van die lewens-balansverskynsel van 24 Suid-Afrikaanse professionele vroue. Die Begronde Teorie as ‘n kwalitatiewe metode is toegepas om ‘n teoretiese model induktief van die verskynsels af te lei. Doelgerigte steekproefneming is gebruik om 24 professionele vroue te identifiseer. In-diepte onderhoude en ‘n groepsessie is gevoer om data in te samel en om die temas en konsepte waarop die teoretiese raamwerk gebaseer is, te bevestig. Daar is tot die slotsom gekom dat lewensbalans ‘n lewensproses is met ‘n sikliese aard en ‘n nuttige instrument om persoonlike groei te bewerkstellig. Lewensbalans is dus nie “een enkele beslissende erevaring" nie, maar ‘n reeks van individuele ervarings wat oor tyd ontvou en wat ten beste beskryf kan word as â

  6. Uitdagings in die onderrig van evolusie in die lewenswetenskappeklaskamer

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    Josef J. de Beer

    2013-02-01

    Full Text Available In hierdie artikel skryf die outeurs oor navorsing wat hulle gedoen het oor onderwysers se siening van die onderrig van evolusie, wat in 2008 as ’n tema in lewenswetenskappe in Suid-Afrikaanse skole ingesluit is. Hierdie vernuwing in die kurrikulum is met gemengde reaksies begroet. Terwyl sommige onderwysers dit met entoesiasme onderrig, is baie gekant teen die onderrig van evolusie. Die artikel is gebaseer op ’n navorsingsprojek waarby 255 onderwysers betrek is. Vraelyste is gebruik om kwalitatiewe data, wat vir diskoers ontleed is, in te samel. Die diskoers van die onderwysers het getoon dat ’n groot getal van hulle nie hul onderrigopdrag kan versoen met hul geloof nie en konsepte oor evolusie as ‘feite’ verduidelik, maar seker maak dat evolusie as ’n teorie gediskrediteer word. Dit het verreikende implikasies vir sowel onderwyseropleiding as kurrikulumontwikkeling. Konseptuele veranderingsteorie word as ’n lens gebruik om na hierdie problematiek te kyk. Challenges in the teaching of evolution in the life sciences classroom. In this article the authors report on research that was conducted about teachers’ views on evolution, which was introduced as a theme in the school life sciences curriculum in 2008. This innovation in the curriculum has been met with mixed reactions. Whereas some teachers embrace this new theme, many teachers are opposed to the teaching of evolution. The article reports on an inquiry that was conducted amongst 255 teachers and in which survey questionnaires were used to collect qualitative data, which was analysed for its discourse. The discourse of the teachers shows that many of them cannot reconcile their religious faith with their teaching and that they may teach the ‘facts’ of evolution, but make sure that they discredit evolution as a theory. This raises serious concerns about teacher education and curriculum development. The authors examine these issues through the lens of conceptual change

  7. Revision of cemented hip arthroplasty using a hydroxyapatite-ceramic-coated femoral component.

    Science.gov (United States)

    Raman, R; Kamath, R P; Parikh, A; Angus, P D

    2005-08-01

    We report the clinical and radiological outcome of 86 revisions of cemented hip arthroplasties using JRI-Furlong hydroxyapatite-ceramic-coated acetabular and femoral components. The acetabular component was revised in 62 hips and the femoral component in all hips. The mean follow-up was 12.6 years and no patient was lost to follow-up. The mean age of the patients was 71.2 years. The mean Harris hip and Oxford scores were 82 (59 to 96) and 23.4 (14 to 40), respectively. The mean Charnley modification of the Merle d'Aubigné and Postel score was 5 (3 to 6) for pain, 4.9 (3 to 6) for movement and 4.4 (3 to 6) for mobility. Migration of the acetabular component was seen in two hips and the mean acetabular inclination was 42.6 degrees. The mean linear polyethylene wear was 0.05 mm/year. The mean subsidence of the femoral component was 1.9 mm and stress shielding was seen in 23 (28%) with bony ingrowth in 76 (94%). Heterotopic ossification was seen in 12 hips (15%). There were three re-revisions, two for deep sepsis and one for recurrent dislocation and there were no re-revisions for aseptic loosening. The mean EuroQol EQ-5D description scores and health thermometer scores were 0.69 (0.51 to 0.89) and 79 (54 to 95), respectively. With an end-point of definite or probable loosening, the probability of survival at 12 years was 93.9% and 95.6% for the acetabular and femoral components, respectively. Overall survival at 12 years, with removal or further revision of either component for any reason as the end-point, was 92.3%. Our study supports the continued use of this arthroplasty and documents the durability of hydroxyapatite-ceramic-coated components.

  8. Individuaalsete töövaidluste lahendamine töövaidluskomisjonis ja selle õigusliku regulatsiooni vastavus Eesti Vabariigi põhiseadusele : [bakalaureusetöö] / Heli Raidve ; Õigusinstituut ; juhendaja: Heino Siigur

    Index Scriptorium Estoniae

    Raidve, Heli

    2002-01-01

    Individuaalse töövaidluse lahendamise korra õiguslik regulatsioon, töövaidluskomisjoni õiguslik seisund ja sõltumatus, individuaalse töövaidluse lahendamise seaduse kohaldamisest töövaidluskomisjonis tekkivad probleemid

  9. Töölepingu lõpetamine töötaja süüteo tõttu : [bakalaureusetöö] / Marili Lämmergas ; Tartu Ülikooli Õigusinstituut ; juhendaja: Heino Siigur

    Index Scriptorium Estoniae

    Lämmergas, Marili

    2005-01-01

    Töötaja töökohustused, töölepingu lõpetamine töötajapoolsel töökohustuste rikkumisel, töötaja suhtes usalduse kaotamisel, töötaja vääritu teo tõttu, vorminõuete rikkumine ja asjaolude tõendamine töölepingu lõpetamisel töötaja süüteo tõttu

  10. Health promotion needs of Hammanskraal families with adolescents orphaned by HIV/AIDS

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    M D Peu

    2008-11-01

    eksplorerend en beskrywend is. Agt families, wat vir die doel geselekteer is, het aan die navorsing deelgeneem. Kwalitatiewe metodes, soos groepsonderhoude en veldnotas, is gebruik om data in te samel. Die gesondheidsorg-behoeftes van die families, met adolessente wat wees gelaat is as gevolg van MIV/VIGS, is ondersoek en beskryf. Tesch se analiseproses, wat uit ‘n aantal stappe bestaan, is gevolg (Creswell, 2003:192. Temas, kategorieë en sub- kategorieë, wat die sentrale fokus van die gesondheidsorgbehoeftes vorm, het uit die data-analise na vore gekom. Hierdie temas, kategorieë en sub-kategorieë, is gebruik om riglyne te ontwikkel vir gesondheidsbevordering.

  11. Non-Dipole Features of the Geomagnetic Field May Persist for Millions of Years

    Science.gov (United States)

    Biasi, J.; Kirschvink, J. L.

    2017-12-01

    Here we present paleointensity results from within the South Atlantic Anomaly (SAA), which is a large non-dipole feature of the geomagnetic field. Within the area of the SAA, anomalous declinations, inclinations, and intensities are observed. Our results suggest that the SAA has been present for at least 5 Ma. This is orders-of-magnitude greater than any previous estimate, and suggests that some non-dipole features do not `average out' over geologic time, which is a fundamental assumption in all paleodirectional studies. The SAA has been steadily growing in size since the first magnetic measurements were made in the South Atlantic, and it is widely believed to have appeared 400 years ago. Recent studies from South Africa (Tarduno et al. (2015)) and Tristan da Cunha (Shah et al. (2016)) have suggested that the SAA has persisted for 1 ka and 96 ka respectively. We conducted paleointensity (PI) experiments on basaltic lavas from James Ross Island, on the Antarctic Peninsula. This large shield volcano has been erupting regularly over the last 6+ Ma (dated via Ar/Ar geochronology), and therefore contains the most complete volcanostratigraphic record in the south Atlantic. Our PI experiments used the Thellier-Thellier method, the IZZI protocol, and the same selection criteria as the Lawrence et al. (2009) study of Ross Island lavas (near McMurdo Station), which is the only comparable PI study on the Antarctic continent. We determined an average paleointensity at JRI of 13.8±5.2 μT, which is far lower than what we would expect from a dipole field (55 μT). In addition, this is far lower than the current value over James Ross Island of 36 μT. These results support the following conclusions: The time-averaged field model of Juarez et al. (1998) and Tauxe et al. (2013) is strongly favored by our PI data. The SAA has persisted over James Ross Island for at least 5 Ma, and has not drifted significantly over that time. The strength of non-dipole features such as the SAA

  12. Sistema reprodutivo e polinização de Lepidagathis sessilifolia (Pohl Kameyama ex Wassh. & J.R.I. Wood (Acanthaceae, em remanescente florestal da região sudoeste de Mato Grosso, Brasil Breeding system and pollination of Lepidagathis sessilifolia (Pohl Kameyama Wassh ex. & J.R.I.Wood (Acanthaceae in remnant forest in the southwest region of Mato Grosso, Brazil

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    Celice Alexandre Silva

    2012-09-01

    Full Text Available O gênero Lepidagathis apresenta distribuição pantropical com cerca de 100 espécies. No Brasil ocorrem 16 espécies, a maioria nas regiões Centro - Oeste e Sudeste. O estudo foi realizado em sub - bosque de remanescente florestal do município de Tangará da Serra - MT e teve como objetivo analisar a fenologia de floração, descrever a morfologia e biologia floral, verificar os visitantes florais e avaliar o sistema e o sucesso reprodutivo por meio de polinizações manuais. Lepidagathis sessilifolia apresenta inflorescências espiciformes, terminais, com cálice de cor rósea vistosa e corola de coloração branco-rósea. A floração ficou restrita aos meses de março a abril, durante a estação chuvosa. A senescência floral ocorreu após 24 ou 48 horas. A viabilidade dos grãos de pólen foi elevada (92,5%. O único polinizador observado visitando as flores de L. sessilifolia foi a abelha Partamona nhambiquara (Apidae - Meliponini. O sistema reprodutivo misto da espécie é caracterizado pela formação de frutos por meio de agamospermia, autopolinização e polinização cruzada. Esse sistema reprodutivo flexível é vantajoso, pois, garante a manutenção da espécie na área de estudo mesmo na ausência de polinizadores.The genus Lepidagathis has pantropical distribution and about 100 species, 16 occurring in Brazil, mostly in the Midwest and Southeast regions. The research was carried out to evaluate in the understory of a forest remnant in Tangará da Serra County - MT to examine the flowering phenology, describe the floral morphology and biology and verify the floral visitors to evaluate the system and reproductive success through hand pollination tests. Lepidagathis sessilifolia shows spiciform and terminal inflorescence with calyx of pink color and corolla whitish-pink. Flowering was restricted from March to April, during the rainy season. Floral senescence occurred after 24 or 48 hours. The viability of pollen grains was high (92.5%. The effective pollinator of L. sessilifolia was Partamona nhambiquara (Apidae - Meliponini. The mixed mating system of the species is characterized by the formation of fruits by agamospermy, self and cross-pollination, spontaneous self-pollination, agamospermy and outcrossing. This flexible reproductive system is advantageous because it ensures the maintenance of species in the study area even in the absence of pollinators.