"ESSAY ON CI" BY LI QINGZHAO

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Anna Dashchenko

2016-10-01

Full Text Available The article presents the first Russian translation of "Essay on Ci" with detailed comments. It was written by the outstanding Chinese poetess Li Qingzhao and considered to be the first theoretical treatise dedicated to genre ci. The article revealed that the poetess used three strategies to make a genre demarcation: to legitimise, dichotomise and historicise. To legitimise means to justify that ci is a genre of poetry by identifying the same traits with official poetry shi (e.g. using the classical quotations and allusions. To dichotomise is to determine a core element of genre and oppose it to the other element identifying the similar genre (e.g. music separates ci from shi. To historicise is to develop or discover the unique historical past (e.g. the source of ci is in antiquity. The article also examined the strategy to invent classics: Li Qingzhao wrote the apophatic history of genre ci pointing not to the merits but weaknesses of her predecessors.

ANALIZA NIEZAWODNOŚCI STACJI UZDATNIANIA WODY

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Barbara TCHÓRZEWSKA-CIEŚLAK

Full Text Available Systemy zbiorowego zaopatrzenia w wodę składają się z połączonych ze sobą elementów (podsystemów stanowiących integralna całość, współpracujących ze sobą w sposób ciągły w celu zapewnienia dla konsumentów wody o odpowiedniej jakości. W przypadku gdy jakość wody w źródle nie odpowiada normatywom stawianym wodzie przeznaczonej do spożycia przez ludzi, woda musi być poddana procesom uzdatniania. Niezawodność funkcjonowania stacji uzdatniania wody jest jednym z podstawowych elementów szeroko rozumianej analizy niezawodności i bezpieczeństwa całego systemu zbiorowego zaopatrzenia w wodę. Niezawodność dostawy wody polega na zapewnieniu stabilnych warunków, umożliwiających pokrycie bieżącego i perspektywicznego zapotrzebowania na wodę w odpowiedniej ilości i wymaganej jakości w dowolnym, dogodnym dla konsumentów wody czasie. W pracy przedstawiono podstawy analizy niezawodności, podano podstawowe miary oraz zasady wykorzystania struktur niezawodnościowych. Obliczenia wykonano dla stacji uzdatniania wody na podstawie schematu niezwodnościowego metodą jednoparametryczną. Na podstawie danych z eksploatacyjnych stacji uzdatniania wody (SUW wchodzącej w skład systemu zbiorowego zaopatrzenia w wodę miasta liczącego ok 80 tys. mieszkańców sporządzono schemat niewodności stacji oraz przeprowadzono obliczenia wskaźnika gotowości K. W metodzie wykorzystano podstawowe struktury niezawodnościowe. Wyznaczoną miarę niezawodności porównano z wartościami kryterialnymi.

A Biblioteconomia e a Ciência da Informação na taxionomia das ciências de Charles Sanders Peirce

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Carlos Cândido de Almeida

2005-07-01

Full Text Available Mostra a taxionomia das ciências desenvolvida por Charles Sanders Peirce (1839-1914 que divide as ciências em três ramos: ciências teóricas, ciências da revisão e ciências aplicadas. Detalha principalmente as ciências teóricas: a Matemática, a Filosofia e a Idioscopia. Discute também o conceito de Biblioteconomia e de Ciência da Informação e que segundo as definições e características, encontradas na literatura consultada, estão na condição de ciências aplicadas, direcionadas a problemas práticos da sociedade, ou seja, o problema de controle e disseminação da informação.

Uwarunkowania skuteczności działania inkubatorów przedsiębiorczości

OpenAIRE

Świeszczak, Krzysztof

2016-01-01

Skłonność społeczeństwa do prowadzenia własnej działalności gospodarczej odgrywa istotną rolę w rozwoju krajowych gospodarek. Biorąc pod uwagę charakterystykę jednostek należących do sektora MSP, ich potrzeby oraz bariery, niekiedy uniemożliwiające egzystencję na rynku, warto zwrócić uwagę na konieczność kreowania narzędzi wspomagających przedsiębiorczość. Spośród licznych instrumentów wsparcia jednostek z sektora MSP na szczególną uwagę zasługują inkubatory przedsiębiorczości , których dział...

As ciências naturais e as ciências do espírito na era da globalização

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Jaeschke, Walter

2006-01-01

Full Text Available Este artigo, o autor apresenta, primeiramente, reflexões de cunho histórico sobre a relação entre as Ciências Naturais e as Ciências do Espírito, seguidas de observações, de caráter mais sistemático, sobre o conceito das próprias Ciências do Espírito. Com fundamento nessas observações, tece algumas reflexões sobre até que ponto podemos esperar da globalização efeitos sobre as Ciências Naturais e as Ciências do Espírito

Measurement of Small Values of Hydrostatic Pressure with the Compensation of Atmospheric Pressure Influence / Pomiar Małych Wartości Ciśnienia Hydrostatycznego Z Kompensacją Wpływu Ciśnienia Atmosferycznego

Science.gov (United States)

Broda, Krzysztof; Filipek, Wiktor

2013-09-01

dalszej części artykułu autorzy przedstawiają przykładową serię pomiarową zwracając uwagę na sposób prowadzenia pomiarów oraz opracowywania wyników tabele 1-3 oraz rysunki 6-8. W tabeli 4 przedstawiono porównanie stanowiska pomiarowego używanego w badaniach poprzednich (Broda i Filipek, 2012) oraz nowego - prezentowanego w artykule. Należy zwrócić uwagę na duże uproszczenie budowy stanowiska przy znacznym wzroście dokładności pomiarów.

Filosofia das ciências sociais: temas atuais

OpenAIRE

Kincaid, Harold

2014-01-01

A filosofia das ciências sociais, concebida da maneira adequada, tem algo a oferecer aos que praticam as ciências sociais. Os cientistas sociais adotam em suas pesquisas, ainda que de forma implícita, alguma filosofia de sua ciência. Para evitar impasses, é melhor explicitar essa filosofia e ser criticamente consciente dos seus méritos. A filosofia das ciências sociais, por sua vez, não pode ser praticada sem um envolvimento íntimo com a pesquisa social. O artigo esboça alguns desenvolvimento...

 Spis treści

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Mieczysław Dobija

2014-04-01

Full Text Available  Od Zespołu Redakcyjnego ............................................................................... 5 Mieczysław Dobija – Rachunkowość w systemie pomiaru aktywności ekonomicznej państwa – Accounting as part of an economic activity measurement system ............... 7 Renata Dyląg, Ewelina Puchalska – Raportowanie zagadnień środowiskowych i społecznych – Reporting on social and environmental issues .............................................. 23 Jacek Gad – Sprawozdanie z wyniku całościowego jako źródło informacji na temat kapitałowych przychodów i kosztów – doświadczenia polskiego i niemieckiego rynku kapitałowego – Statement of comprehensive income as a source of information on capital income and expenses – experience of Polish and German capital markets...... 47 Piotr Luty – Ocena kondycji finansowej łączących się spółek na przykładzie jednostek z wybranych województw Polski Zachodniej – Assessment of financial position of merging companies based on selected provinces of Western Poland ............................................................................ 69 Irena Sobańska – Znaczenie dorobku naukowego Profesor Elżbiety Burzym dla rozwoju nauki i praktyki rachunkowości w Polsce – The importance of Professor Elżbieta Burzym’s contribution to the development of accounting theory, research and practice in Poland ........................ 83 Arleta Szadziewska – Rachunkowość jako źródło informacji na temat realizacji strategii społecznej odpowiedzialności biznesu – Accounting as a source of information for CSR strategy ............................. 95 Halina Waniak-Michalak – Informacja o pracy wolontariuszy w sprawozdaniach organizacji pożytku publicznego w Polsce – Information on volunteer labour in reports of public benefit organizations in Poland ............................................................................................................ 125

Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice

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Rafael Almeida-Reis

2017-01-01

Full Text Available Background. Proteinases play a key role in emphysema. Bauhinia bauhinioides cruzipain inhibitor (BbCI is a serine-cysteine proteinase inhibitor. We evaluated BbCI treatment in elastase-induced pulmonary alterations. Methods.  C57BL/6 mice received intratracheal elastase (ELA group or saline (SAL group. One group of mice was treated with BbCI (days 1, 15, and 21 after elastase instillation, ELABC group. Controls received saline and BbCI (SALBC group. After 28 days, we evaluated respiratory mechanics, exhaled nitric oxide, and bronchoalveolar lavage fluid. In lung tissue we measured airspace enlargement, quantified neutrophils, TNFα-, MMP-9-, MMP-12-, TIMP-1-, iNOS-, and eNOS-positive cells, 8-iso-PGF2α, collagen, and elastic fibers in alveolar septa and airways. MUC-5-positive cells were quantified only in airways. Results. BbCI reduced elastase-induced changes in pulmonary mechanics, airspace enlargement and elastase-induced increases in total cells, and neutrophils in BALF. BbCI reduced macrophages and neutrophils positive cells in alveolar septa and neutrophils and TNFα-positive cells in airways. BbCI attenuated elastic and collagen fibers, MMP-9- and MMP-12-positive cells, and isoprostane and iNOS-positive cells in alveolar septa and airways. BbCI reduced MUC5ac-positive cells in airways. Conclusions. BbCI improved lung mechanics and reduced lung inflammation and airspace enlargement and increased oxidative stress levels induced by elastase. BbCI may have therapeutic potential in chronic obstructive pulmonary disease.

Hírpiacok szimulációja

OpenAIRE

Németh, András

2005-01-01

Hírtőzsdén olyan, általában elektronikus piacot értünk, ahol különféle jövőbeli eseményekre lehet fogadni. Mint azt már több vizsgálat is megmutatta, ezek a játéktőzsdék alkalmasak arra, hogy a résztvevők rendelkezésére álló elszórt részinformációkat összegyűjtsék, egyetlen árfolyammá alakítsák (információaggregáció), és ezzel előre jelezzék az eseményeket. Jelen tanulmány célja e hírtőzsdék és szereplőinek modellezése, valamint az információaggregáció vizsgálata. Ennek érdekében felépítünk e...

Wartości poznawcze sprawozdawczości regulacyjnej podmiotu świadczącego powszechne usługi pocztowe

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Leszek Borowiec

2018-03-01

Full Text Available Ze względu na aspekty strategiczne, gospodarcze czy społeczne, niektóre obszary aktywności przedsiębiorstw w gospodarce rynkowej są organizowane w ramach tzw. rynków regulowanych. Regulacja danej części rynku najczęściej podlega dodatkowym rygorom sprawozdawczości. Celem artykułu jest próba oceny wartości poznawczych sprawozdawczości z rachunkowości regulacyjnej operatora wyznaczonego do świadczenia powszechnych usług pocztowych. W opracowaniu dokonano przeglądu uwarunkowań prawnych działania operatora wyznaczonego oraz scharakteryzowano zakres ujawnianych informacji w sprawozdawczości regulacyjnej, na przykładzie rynku pocztowych usług powszechnych. Podstawą analizy były sprawozdania regulacyjne składne przez operatora wyznaczonego, tj. Pocztę Polską. Wopracowaniu zastosowano takie metody badawcze jak: studia literaturowe, analiza aktów prawnych regulujących rynek usług pocztowych, wywiady oraz badanie poprzez działanie. Konkluzje skłaniają do stwierdzenia, iż sprawozdawczość regulacyjna, mimo swojej specyfiki, dla regulatora rynku stanowi istotne źródło informacji do oceny efektywności świadczonych usług. Jednocześnie ma bardzo wątpliwe walory poznawcze dla interesariuszy zewnętrznych, ze względu na szeroki zakres stosowania instytucji „tajemnicy przedsiębiorstwa”. Artykuł jest oryginalnym spojrzeniem autora na słabo rozpoznany od strony naukowej problem wartości informacyjnej dla interesariuszy sprawozdawczości podmiotów działających w sektorach regulowanych. For strategic, economic or social reasons, some areas of business activity in the market economy are organized under the so-called regulated markets. The regulation of a given part of the market is most often subject to additional reporting requirements. The aim of this article is to try to assess the cognitive value of reporting from the regulatory accounting of an operator designated to provide universal postal services. The

Dylematy standaryzacjisprawozdawczości finansowej,wyceny i pomiaru ryzyka

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Dorota Dobija

2010-09-01

Full Text Available W artykule zostały poruszone zagadnienia związane z istotą przejrzystości fi-nansowej organizacji. Przejrzystość ta jest jednym z elementów efektywnego systemu ładu korporacyjnego, dlatego tempo zmian w tym obszarze jest narzucone przez refor-my w systemach ładu korporacyjnego. W pierwszej części opracowania jest dyskuto-wana rola menedżerów w zapewnieniu przejrzystości finansowej organizacji. Kolejna część opracowania obejmuje krytyczną dyskusję trzech istotnych wątków teore-tycznych wpływających na jakość sprawozdawczości: postępującej standaryzacji w rachunkowości, problemów wyceny w rachunkowości oraz zagadnień pomiaru i sprawozdawczości ryzyka w organizacji.

DNA damage in isolated rat hepatocytes exposed to C.I. pigment orange 5 and C.I. pigment yellow 12 by the alkaline comet assay

DEFF Research Database (Denmark)

Møller, P; Wallin, Håkan; Grunnet, N

1998-01-01

The induction of DNA damage by commonly used printing ink pigments, C.I. pigment orange 5 (C.I. 12075) and C.I. pigment yellow 12 (C.I. 21090), was investigated in freshly isolated rat hepatocytes with the comet assay. C.I. pigment yellow 12 is a 3,3'-dichlorobenzidine-based diarylide pigment...

Comparative evaluation of the two methods of fixed dose radioiodine therapy (5 mCi and 10 mCi) for the treatment of Graves' disease

International Nuclear Information System (INIS)

Fard Esfehani, A.; Dabbagh Kakhki, V.R.; Eftekhari, M.; Zarpak, B.; Fallahi Seyjani, B.; Saghari, M.

2002-01-01

Radioiodine therapy is the safest, simplest, least expensive and most effective method for treatment in most patients with Graves' disease. Due to complexity of methods for dose determination, the tendency is toward using fixed doses of I-131 for this purpose. As there is conflict for the best fixed dose, regarding it's efficiency and complication of hypothyroidism, standardized dose selection is of particular importance in treatment of Grave' disease. 59 patients with grave' disease, referred to the nuclear medicine center of Shariati Hospital from 78.5.25 were studied. In this clinical trial, the patients were randomized into two groups, one were treated with 5 mCi of 1-131 and the other received 10 mCi of the same agent. All patients were followed for two years, with 6-month intervals. Among 65 patients treated with I-131, 20 (33 9%) patients became euthyroid and 19(32.2%) became hypothyroid while relapse was noticed in 20 patients (33.9%) In The group treated by 5 mCi I-131 (33 patients), 10(30%) were euthyroid, 6(18.2%) were hypothyroid (overall cure of 48.5% while 17(51.5%) remained hyperthyroid by the end of the follow -up period(two years). From the 26 patients who were treated with 10 mCi, the euthyroid, hypothyroid and hypothyroid states were observed in 10(38.5%), 13(50%), 13(50%) and 3(11.5%) patients respectively (with an overall cure rate of 88.5%). No relationship was noted between the outcome and age, sex, size of the thyroid gland and thyroid uptake, but the relationship between the disease outcome and the amount of administered radioiodine was statistically significant (P=0.003). For most of the patients, age, sex, iodine uptake and even thyroid size play minor roles in dose selection. Although the incidence-rate of early hypothyroidism (by the end of 2 years) in the cases related with 5 mCi is less than those treated with 10 mCi, the incidence of relapse is greatly higher in the former group. In addition, it was found that long

Identification of two CiGADs from Caragana intermedia and their transcriptional responses to abiotic stresses and exogenous abscisic acid.

Science.gov (United States)

Ji, Jing; Zheng, Lingyu; Yue, Jianyun; Yao, Xiamei; Chang, Ermei; Xie, Tiantian; Deng, Nan; Chen, Lanzhen; Huang, Yuwen; Jiang, Zeping; Shi, Shengqing

2017-01-01

Glutamate decarboxylase (GAD), as a key enzyme in the γ -aminobutyric acid (GABA) shunt, catalyzes the decarboxylation of L-glutamate to form GABA. This pathway has attracted much interest because of its roles in carbon and nitrogen metabolism, stress responses, and signaling in higher plants. The aim of this study was to isolate and characterize genes encoding GADs from Caragana intermedia , an important nitrogen-fixing leguminous shrub. Two full-length cDNAs encoding GADs (designated as CiGAD1 and CiGAD2 ) were isolated and characterized. Multiple alignment and phylogenetic analyses were conducted to evaluate their structures and identities to each other and to homologs in other plants. Tissue expression analyses were conducted to evaluate their transcriptional responses to stress (NaCl, ZnSO 4 , CdCl 2 , high/low temperature, and dehydration) and exogenous abscisic acid. The CiGAD s contained the conserved PLP domain and calmodulin (CaM)-binding domain in the C-terminal region. The phylogenetic analysis showed that they were more closely related to the GADs of soybean, another legume, than to GADs of other model plants. According to Southern blotting analysis, CiGAD1 had one copy and CiGAD2 -related genes were present as two copies in C. intermedia . In the tissue expression analyses, there were much higher transcript levels of CiGAD2 than CiGAD1 in bark, suggesting that CiGAD2 might play a role in secondary growth of woody plants. Several stress treatments (NaCl, ZnSO 4 , CdCl 2 , high/low temperature, and dehydration) significantly increased the transcript levels of both CiGAD s, except for CiGAD2 under Cd stress. The CiGAD1 transcript levels strongly increased in response to Zn stress (74.3-fold increase in roots) and heat stress (218.1-fold increase in leaves). The transcript levels of both CiGAD s significantly increased as GABA accumulated during a 24-h salt treatment. Abscisic acid was involved in regulating the expression of these two CiGAD s under salt

Probing Signatures of a Distant Planet around the Young T-Tauri Star CI Tau Hosting a Possible Hot Jupiter

Science.gov (United States)

Konishi, Mihoko; Hashimoto, Jun; Hori, Yasunori

2018-06-01

We search for signatures of a distant planet around the two million-year-old classical T-Tauri star CI Tau hosting a hot-Jupiter candidate ({M}{{p}}\\sin i∼ 8.1 {M}Jupiter}) in an eccentric orbit (e ∼ 0.3). To probe the existence of an outer perturber, we reanalyzed 1.3 mm dust continuum observations of the protoplanetary disk around CI Tau obtained by the Atacama Large Millimeter/submillimeter Array (ALMA). We found a gap structure at ∼0.″8 in CI Tau’s disk. Our visibility fitting assuming an axisymmetric surface brightness profile suggested that the gap is located at a deprojected radius of 104.5 ± 1.6 au and has a width of 36.9 ± 2.9 au. The brightness temperature around the gap was calculated to be ∼2.3 K lower than that of the ambient disk. Gap-opening mechanisms such as secular gravitational instability (GI) and dust trapping can explain the gap morphology in the CI Tau disk. The scenario that an unseen planet created the observed gap structure cannot be ruled out, although the coexistence of an eccentric hot Jupiter and a distant planet around the young CI Tau would be challenging for gravitational scattering scenarios. The mass of the planet was estimated to be between ∼0.25 M Jupiter and ∼0.8 M Jupiter from the gap width and depth ({0.41}-0.06+0.04) in the modeled surface brightness image, which is lower than the current detection limits of high-contrast direct imaging. The young classical T-Tauri CI Tau may be a unique system for exploring the existence of a potential distant planet as well as the origin of an eccentric hot Jupiter.

Structural Biology of CI from Phage TP901-1

DEFF Research Database (Denmark)

Rasmussen, Kim Krighaar

(CTD), separated by a linker of various lengths. The NTD is responsible for DNA binding and the CTD is responsible for oligomerization of the CI protein. A Helix-turn-Helix motif is usually responsible for DNA binding. This thesis presents a structural characterization of the CI repressor from TP901...... condition of the CTD, responsible for the arrangement of the hexameric CI repressor. The arrangement of the CI repressor for TP901-1 has previously been described to have 32 point group symmetry based on SAXS studies. The CTD crystallizes with P3121 or P3221 symmetry with one molecule in the asymmetric unit......-length CI can only be answered unambiguously by solving the CTD crystal structure or by use of alternative techniques on the full-length CI....

As tendências atuais dos paradigmas: ciência, tecnologia e sociedade e ensino de ciências indígena no VII ENPEC

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Maria Delourdes Maciel

2014-01-01

Full Text Available O Encontro Nacional de Pesquisas em Educação em Ciências é um evento bianual organizada pelos pesquisadores do ensino de Ciências. O objetivo principal desse encontro é reunir os professores e pesquisadores da área, para socializarem os relatos de experiência e pesquisas no ensino de Ciências. Nesse presente trabalho, foi realizado um mapeamento dos artigos apresentados nas seções de comunicação oral do VII ENPEC, somando um total de 425 artigos selecionados, procurou-se identificar os relacionados com a abordagem Ciências, Tecnologia e Sociedade (CTS no ensino de Ciências sua estrutura de organização e o numero de pesquisadores dessa área do Ensino de Ciências. Para esse estudo foi realizado uma pesquisa qualitativa de caráter bibliográfico, e para a análise dos dados buscou-se subsídios teóricos em Fiorentini (2002 e Bardin (2006 porque assim seria possível comparar minuciosamente os diferentes resultados obtidos. Conclui-se que a linha de pesquisa com a temática CTS apresentou 28 trabalhos cerca de 7% de trabalhos apresentados, confirmando uma sinalização nessa área de pesquisa pelos pesquisadores do ensino de Ciências e a temática sobre ensino de ciências indígena representou cerca de 1% dos trabalhos apresentados.

BIOGRAMY POLSKICH MYŚLICIELI NIERUCHOMOŚCI

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Edyta Łazarowicz

2009-11-01

Full Text Available Fragment artykułu: [b]Andrzej Bieniek[/b] (1895-1944, doktor, urodził się 17 października 1895 r. w Bratucicach (powiat Bochnia, rozstrzelany 26 lipca 1944 roku w ruinach getta w Warszawie. (...Doktor A. Bieniek zajmował się głównie problemami organizacji księgowości w przedsiębiorstwach oraz rachunkiem kosztów. Był autorem m.in. następujących publikacji: Polska metoda księgowości oparta na ekonomicznym systemie Taylora (Biblioteka Państwowej Szkoły Handlowej Męskiej w Łodzi, Łódź 1927, Kantor wzorowy w szkołach handlowych (Biblioteka Państwowej Szkoły Handlowej Męskiej w Łodzi, Warszawa-Łódź 1928, Księgowość w przedsiębiorstwach przemysłowych (Biblioteka Rady Głównej Zrzeszeń Księgowych i Rzeczoznawców Księgowości w Polsce, Warszawa 1935, Zasady inwentaryzacji i bilansowania (Związek Księgowych w Polsce, Warszawa 1936, Organizacja rachunkowości w przedsiębiorstwach przemysłowych ((Związek Księgowych w Polsce, Warszawa 1939, Zasady analizy bilansów (Stowarzyszenie Nauczycieli Szkół Zawodowych. Sekcja Główna Handlowa, Warszawa 1939. [b]Zygmunt Stefan Kossut[/b] (1922–1984 profesor doktor habilitowany, syn Wiktora Kossuta i Henryki Serafin, urodził się 16 kwietnia 1922 r. (.. Do dzisiaj znane jest profesjonalistom zdanie E. Terebuchy, że „on pierwszy (Z. Kossut – M.G. przeorał ugór w naszej nauce rachunkowości, wykonując próbę sformułowania nowych poglądów na metody badawcze w dziedzinie teorii rachunkowości.” [b]Kazimierz Sowa[/b] (1915–1972, profesor nadzwyczajny, doktor, urodził się 2 października 1915 roku w Krakowie w rodzinie chłopskiej, zmarł 17 grudnia 1972 r. w Krakowie. Był żonaty, bezdzietny. (... Okres pracy zawodowej Kazimiera Sowy (1938–1972 był bardzo zróżnicowany i przebiegał wielotorowo. Była to praca naukowo-dydaktyczna w szkolnictwie wyższym, praca redakcyjno-popularyzatorska, organizacyjno-kierownicza w Stowarzyszeniu Księgowych w

Language Practices in the Ci-Classroom

DEFF Research Database (Denmark)

Mourtou, Eleni

2014-01-01

Prelingually deafened children are nowadays likely to receive a cochlear implant (ci). As these children do their language acquisition with a cochlear implant they require a constant rehabilitation and support. Educational staff is instructed on how to work with children with ci in form...... of guidelines and workshops. This paper discusses language practices used in the setting of a school for cochlear-implanted children. These children encounter language and pronunciation problems that accompany prelingual deafness and hearing with a cochlear implant. I examine two practices, which are used...

Spectral reflectance properties of carbonaceous chondrites: 1. CI chondrites

Science.gov (United States)

Cloutis, E. A.; Hiroi, T.; Gaffey, M. J.; Alexander, C. M. O.'D.; Mann, P.

2011-03-01

Existing reflectance spectra of CI chondrites (18 spectra of 3 CIs) have been augmented with new (18 spectra of 2 CIs) reflectance spectra to ascertain the spectral variability of this meteorite class and provide insights into their spectral properties as a function of grain size, composition, particle packing, and viewing geometry. Particle packing and viewing geometry effects have not previously been examined for CI chondrites. The current analysis is focused on the 0.3-2.5 μm interval, as this region is available for the largest number of CI spectra. Reflectance spectra of powdered CI1 chondrites are uniformly dark (IOM), as no other CI opaque phase appears able to produce concurrent darkening and bluing. Magnetite can also explain the presence of an absorption feature near 1 μm in some CI spectra. The most blue-sloped spectra are generally associated with the larger grain size samples. For incidence and emission angles <60°, increasing phase angle results in darker and redder spectra, particularly below ∼1 μm. At high incidence angles (60°), increasing emission angle results in brighter and redder spectra. More densely packed samples and underdense (fluffed) samples show lower overall reflectance than normally packed and flat-surface powdered samples. Some B-class asteroids exhibit selected spectral properties consistent with CI chondrites, although perfect spectral matches have not been found. Because many CI chondrite spectra exhibit absorption features that can be related to specific mineral phases, the search for CI parent bodies can fruitfully be conducted using such parameters.

Farmakogenetyczne uwarunkowania lekooporności w padaczce

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Alicja Kozera-Kępniak

2013-06-01

Full Text Available Padaczka jest jedną z najczęstszych chorób ośrodkowego układu nerwowego, występującą u około 1% populacji na świecie. Charakteryzuje się występowaniem nawracających napadów o różnej symptomatologii. Szacuje się, że u 30% pacjentów mimo prowadzonego właściwego leczenia przeciwpadaczkowego nadal występują napady drgawkowe. Jest to tak zwane zjawisko lekooporności. W Polsce problem ten dotyczy około 100 000–120 000 chorych. Czynnikami predysponującymi do wystąpienia padaczki lekoopornej są: ujawnienie się choroby przed 1. rokiem życia, duża częstotliwość napadów przed rozpoczęciem leczenia oraz zmiany strukturalne mózgu, w tym wady rozwojowe kory mózgowej. Niekontrolowane napady padaczkowe pogarszają jakość życia chorych, zwiększając ryzyko urazów, wpływając negatywnie na samopoczucie fizyczne oraz funkcjonowanie psychospołeczne. Chociaż znane są potencjalne czynniki ryzyka, to nadal nie wiadomo, dlaczego u dwóch pacjentów z tym samym rodzajem padaczki lub tym samym typem napadów skuteczność leczenia lekami przeciwpadaczkowymi może być skrajnie różna. Wśród możliwych przyczyn tego zjawiska wymienia się czynniki genetyczne, zmieniające właściwości farmakodynamiczne i farmakokinetyczne stosowanych leków. Do grupy tych czynników zalicza się: genetycznie uwarunkowany polimorfizm niektórych enzymów mikrosomalnych (CYP2C9, CYP2C19, glikoproteiny P, białka MRP (multidrug resistance-associated protein oraz zaburzenia funkcji farmakodynamicznych receptorów GABA (GABAA i kana- łów jonowych. Wydaje się, że badania nad mechanizmami lekooporności mogą skutkować wprowadzeniem nowych strategii terapeutycznych. Niniejszy artykuł ma na celu przedstawienie wpływu powyżej wymienionych czynników genetycznych na brak skuteczności leczenia w padaczce.

Analysis of factors affecting the outcome of Graves disease patients treated with two regimens of fixed Iodine-131 doses (10 mCi and 15 mCi)

International Nuclear Information System (INIS)

Machado, Ana C.B.; Santos, Roberto B.; Chaves, Fatima R.; Romaldini, Joao H.; Ward, Laura S.

2005-01-01

Full text: The use of fixed doses of radioiodine ( 131 I) simplifies the approach to treatment for Graves' disease (GD) patients with potential cost savings. In order to evaluate factors that may affect the outcome of 2 different regimens of 131 I, we prospectively examined 128 patients with overt thyrotoxicosis from GD, as confirmed by suppressed serum TSH, presence of TRAb, increased serum T 3 and FT 4 values. Group 1 comprised 76 patients who received a fixed dose of 10 mCi and Group 2=52 patients who received a fixed dose of 15 mCi. 36 patients did not use any antithyroid drugs and 92 patients used methimazole that was withdrawn at least 5 days before radioiodine administration. Antithyroid drugs treatment was restarted at least 7 days following 131 I therapy when needed. Baseline serum TSH and FT 4 levels were measured at 3, 6, 9 and 12 months after treatment. The groups were similar concerning age, gender, smoke, eye disease, goiter size, serum T 3 , FT 4 , TRAb, anti-Tg and anti-TPO levels as well as 24-hour 131 I or Tec-uptake values and thyroid scan. Clinical outcome was evaluated at the end of 1-year follow-up and cure of hyperthyroidism was defined as clinical and laboratory evidence of either euthyroidism or hypothyroidism in the absence of antithyroid drugs. The cure rate obtained was similar in groups 1 and 2: 73.7% and 80.8%, respectively (p=0.35). Hypothyroidism was diagnosed in 56.5% and 71.15% of the patients from groups 1 and 2, respectively (p=0.13). There was no correlation between clinical features, thyroid uptake, antibodies, serum hormones and outcome. However, logistic regression analysis demonstrated that patients with larger thyroids (weight >60 g) that, consequently, received a lower dose of radioiodine in MBq/g, had 2.4 times less chance to cure (95% Cl=1.18-4.96). The use of fixed doses of radioiodine ( 131 I) simplifies the approach to treatment for Graves' disease (GD) patients with potential cost savings. In order to evaluate

Konwergencja rachunkowości finansowej i rachunkowości zarządczej w Polsce w świetle badań ankietowych

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Przemysław Kabalski

2018-03-01

Full Text Available Celem artykułu jest określenie stopnia konwergencji rachunkowości finansowej i rachunkowości zarządczej w przedsiębiorstwach w Polsce. Do zbadania stopnia konwergencji wykorzystano metodę sondażową z zastosowaniem kwestionariusza ankiety. Okazało się, że poziom konwergencji rachunko- wości w badanych przedsiębiorstwach jest umiarkowany. Badania konwergencji rachunkowości na świecie nie są liczne, a w Polsce ‒ zupełnie wyjątkowe. Z tego względu badanie prezentowane w artykule jest istotne zarówno dla nauki, jak i praktyki rachunkowości. The aim of the article is to determine the level of convergence of financial accounting and management accounting in companies operating in Poland. In order to determine the level of the convergence, the survey method was used. It was found that the level of convergence of accounting in the companies examined is moderate. The number of studies on the convergence of accounting is very limited in the world, and in Poland they are quite unique. For this reason, the research presented in this article is rele- vant for both the science and the practice of accounting.

VELoCiRaPTORS.

Science.gov (United States)

Lundgren, J.; Esham, B.; Padalino, S. J.; Sangster, T. C.; Glebov, V.

2007-11-01

The Venting and Exhausting of Low Level Air Contaminants in the Rapid Pneumatic Transport of Radioactive Samples (VELoCiRaPTORS) system is constructed to transport radioactive materials quickly and safely at the NIF. A radioactive sample will be placed inside a carrier that is transported via an airflow system produced by controlled differential pressure. Midway through the transportation process, the carrier will be stopped and vented by a powered exhaust blower which will remove radioactive gases within the transport carrier. A Geiger counter will monitor the activity of the exhaust gas to ensure that it is below acceptable levels. If the radiation level is sufficient, the carrier will pass through the remainder of the system, pneumatically braking at the counting station. The complete design will run manually or automatically with control software. Tests were performed using an inactive carrier to determine possible transportation problems. The system underwent many consecutive trials without failure. VELoCiRaPTORS is a prototype of a system that could be installed at both the Laboratory for Laser Energetics at the University of Rochester and the National Ignition Facility at LLNL.

Cognitivismo e ciência cognitiva

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Marcos Barbosa de Oliveira

1990-01-01

Full Text Available O objetivo da comunicação é caracterizar uma escola de pensamento-o cognitivismo-e a disciplina a que ela deu origem. Depois de um breve apanhado das origens do cognitivismo descrevem-se os princípios ontológicos e metodológicos que o definem. Mostra-se a seguir a relação que há entre os computadores e a idéia funcionalista de considerar a mente como um sistema cujos elementos são caracterizados por suas funções, e não por sua constituição material. Discute-se finalmente a natureza e o nome da disciplina gerada pelo cognitivismo, sugerindo-se que se trata de uma proto-ciência, a qual deve ser denominada "Estudos Cognitivos" de preferência a "Ciência Cognitiva".

Dietary Salt Restriction in Chronic Kidney Disease: A Meta-Analysis of Randomized Clinical Trials.

Science.gov (United States)

Garofalo, Carlo; Borrelli, Silvio; Provenzano, Michele; De Stefano, Toni; Vita, Carlo; Chiodini, Paolo; Minutolo, Roberto; Nicola, Luca De; Conte, Giuseppe

2018-06-06

A clear evidence on the benefits of reducing salt in people with chronic kidney disease (CKD) is still lacking. Salt restriction in CKD may allow better control of blood pressure (BP) as shown in a previous systematic review while the effect on proteinuria reduction remains poorly investigated. We performed a meta-analysis of randomized controlled trials (RCTs) evaluating the effects of low versus high salt intake in adult patients with non-dialysis CKD on change in BP, proteinuria and albuminuria. Eleven RCTs were selected and included information about 738 CKD patients (Stage 1⁻4); urinary sodium excretion was 104 mEq/day (95%CI, 76⁻131) and 179 mEq/day (95%CI, 165⁻193) in low- and high-sodium intake subgroups, respectively, with a mean difference of −80 mEq/day (95%CI from −107 to −53; p <0.001). Overall, mean differences in clinic and ambulatory systolic BP were −4.9 mmHg (95%CI from −6.8 to −3.1, p <0.001) and −5.9 mmHg (95%CI from −9.5 to −2.3, p <0.001), respectively, while clinic and ambulatory diastolic BP were −2.3 mmHg (95%CI from −3.5 to −1.2, p <0.001) and −3.0 mmHg (95%CI from −4.3 to −1.7; p <0.001), respectively. Mean differences in proteinuria and albuminuria were −0.39 g/day (95%CI from −0.55 to −0.22, p <0.001) and −0.05 g/day (95%CI from −0.09 to −0.01, p = 0.013). Moderate salt restriction significantly reduces BP and proteinuria/albuminuria in patients with CKD (Stage 1⁻4).

Implications of CI therapy for Visual Deficit Training

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Edward eTaub

2014-10-01

Full Text Available We address here the question of whether the techniques of CI therapy, a family of treatments that has been employed in the rehabilitation of movement and language after brain damage might apply to the rehabilitation of such visual deficits as unilateral spatial neglect and visual field deficits. CI therapy has been used successfully for the upper and lower extremities after chronic stroke, cerebral palsy (CP, multiple sclerosis (MS, other CNS degenerative conditions, resection of motor areas of the brain, focal hand dystonia, and aphasia. Treatments making use of similar methods have proven efficacious for amblyopia.The CI therapy approach consists of four major components: intensive training, training by shaping, a transfer package to facilitate the transfer of gains from the treatment setting to everyday activities, and strong discouragement of compensatory strategies.CI therapy is said to be effective because it overcomes learned nonuse, a learned inhibition of movement that follows injury to the CNS. In addition, CI therapy produces substantial increases in the grey matter of motor areas on both sides of the brain. We propose here that these mechanisms are examples of more general processes: learned nonuse being considered parallel to sensory nonuse following damage to sensory areas of the brain, with both having in common diminished neural connections (DNC in the nervous system as an underlying mechanism. CI therapy would achieve its therapeutic effect by strengthening the diminished neural connections. Use-dependent cortical reorganization is considered to be an example of the more general neuroplastic mechanism of brain structure repurposing (BSR. If the mechanisms involved in these broader categories are involved in each of the deficits being considered, then it may be the principles underlying efficacious treatment in each case may be similar. The lessons learned during CI therapy research might then prove useful for the treatment of

Wykorzystanie informacji prospektywnychw sprawozdawczości finansowej zorientowanejna wartość na przykładzie MSR 36„Utrata wartości aktywów”

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Irena Sobańska

2009-12-01

Full Text Available Autorzy artykułu wskazują na istotę i rosnące znaczenie informacji prospektywnych we współczesnych systemach sprawozdawczości finansowej opartej na MSSF. Ewolucja dokonująca się w sprawozdawczości finansowej, pod wpływem harmonizacji zasad rachunkowości wskutek ciągle zmieniających się MSSF, została przedstawiona na tle zmian dokonujących się w otoczeniu, w celach i w systemach zarządzania (orientacja strategiczna, wartość przedsiębiorstwa, jak również w systemach strategicznej rachunkowości zarządczej. Na podstawie szerokiego kontekstu analizy autorzy stawiają wniosek, że koncepcja wartości (przedsiębiorstwa stanowi istotny element systemu pomiaru i wyceny w systemie sprawozdawczości finansowej. Tworzy ona także spójną podstawę dla integracji rachunkowości zarządczej i rachunkowości finansowej w jeden system zapewniający użyteczne informacje zarówno dla użytkowników zewnętrznych, jak i wewnętrznych, których łączy wspólny cel – maksymalizacja wartości. Uwarunkowania tworzenia systemu sprawozdawczości opartego na informacjach prospektywnych, zorientowanego na wartość, jak również stopień dostosowania przedsiębiorstw do jego wdrożenia pokazano na przykładzie praktycznej realizacji postanowień MSR 36.

21 CFR 73.3112 - C.I. Vat Orange 1.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 1 2010-04-01 2010-04-01 false C.I. Vat Orange 1. 73.3112 Section 73.3112 Food... COLOR ADDITIVES EXEMPT FROM CERTIFICATION Medical Devices § 73.3112 C.I. Vat Orange 1. (a) Identity. The color additive is C.I. Vat Orange 1, Colour Index No. 59105. (b) Uses and restrictions. (1) The...

Nowe zasady działalności firm audytorskich

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Kazimierz Sawicki

2009-03-01

Full Text Available W artykule przedstawiono zmiany, stanowiące implementację Dyrektywy 2006/43/WE Unii Europejskiej w części dotyczącej funkcjonowania firm audytorskich w Polsce. Zgłoszono uwagi popierające nowe rozwiązania, jak też zawierające wątpliwości dotyczące skuteczności ich stosowania w praktyce.

Dual inhibitory action of enadoline (CI977) on release of amino acids in the rat hippocampus.

Science.gov (United States)

Millan, M H; Chapman, A G; Meldrum, B S

1995-06-06

The effect of the kappa-opioid receptor agonist enadoline (CI977, (5R)-(5 alpha,7 alpha,8 beta)-N-methyl-N-[7-(1-pyrrilidinyl)-1-oxaspiro [4,5]dec-8-yl-4-benzofuranacetamide monohydrochloride), on the release of amino acids was studied in the hippocampus of freely moving rats. K+, 100 mM, or veratrine, 100 microM, were applied for 10 min via the dialysis probe, either alone (control groups) or together with CI977 (after a 10 min pretreatment with CI977 in the perfusion medium). To test the specificity of the response to CI977, nor-binaltorphimine, a selective kappa-opioid receptor antagonist, was delivered together with CI977 in two groups of animals. To test the effect of systemic injection, CI977 was given subcutaneously 30 min prior to either stimulus. K(+)-induced release of glutamate and aspartate was significantly reduced by CI977, 2.5 mM; release of gamma-aminobutyric acid (GABA) was reduced by 250 microM CI977 in the probe. The effect of CI977 on release of glutamate and aspartate, but not of GABA, was reversed by nor-binaltorphimine (45 microM). Systemic treatment with CI977, 1 or 10 mg/kg, did not reduce K(+)-induced release of glutamate. Veratrine-induced release of aspartate and glutamate was significantly inhibited by 25 microM and release of GABA by 250 microM CI977 in the probe, and this effect was not modified by nor-binaltorphimine (58 microM). Systemic injection of CI977 1 mg/kg significantly reduced veratrine-induced release of glutamate. These results indicate that CI977 regulates release of amino acids by two independent mechanisms.(ABSTRACT TRUNCATED AT 250 WORDS)

O Jornal Nacional e a Ciência

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Diego Andres Salcedo

2009-10-01

Full Text Available Entendendo a informação científica como aquela capaz de contribuir para o desenvolvimento de uma cultura científica, analisamos neste trabalho aspectos relacionados à presença da informação sobre ciência no Jornal Nacional (JN, da Rede Globo de Televisão. A partir da observação do noticiário veiculado de 1º de janeiro a 31 de março de 2007, foi possível identificar 88 matérias que traziam informações relacionadas à ciência. O corpus nos permitiu categorizar os tipos de inserção da ciência no JN, esboçar o interesse do JN pelos temas científicos e discutir seu papel na formação de uma cultura científica do povo brasileiro.

Ocena czynności nerek u dzieci leczonych metodę ESWL - doniesienie wstępne

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Ewa Straż-Żebrowska

2010-06-01

Full Text Available Kamica układu moczowego jest chorobą polegającą na tworzeniu się złogów w drogach moczowych w momencie zaburzenia równowagi pomiędzy promotorami i inhibitorami krystalizacji. Obecnie obserwuje się narastanie częstości występowania kamicy w społeczeństwach krajów wysoko uprzemysłowionych, w tym również w populacji dziecięcej. Problem ten dotyczy nawet 5% tej populacji, a coraz większą grupę stanowią dzieci w okresie niemowlęcym. Wśród metod leczenia wyróżniamy postępowanie zachowawcze lub zabiegowe. Leczeniu zachowawczemu najczęściej poddaje się złogi o średnicy do 5 mm, większe wymagają zastosowania metod inwazyjnych. Wśród metod zabiegowych wyróżniamy metody stosunkowo mało inwazyjne, takie jak: ESWL (kruszenie złogów falą generowaną pozaustrojowo, PCNL (przezskóma nefrolitotrypsja, LTRSL (endoskopowa litotrypsja. Obecnie znacznie rzadziej stosowane jest leczenie operacyjne. Zabieg ESWL poprzez działanie fali uderzeniowej powoduje dezintegrację złogu. Cel: Ocena bezpieczeństwa metody w aspekcie funkcji nerek u dzieci leczonych z powodu kamicy układu moczowego metodą ESWL. Materia! i metody: Badaniem objęto 16 dzieci (7 chłopców i 9 dziewczynek w wieku od 2,5 do 17,5 roku (średni wiek 9,5 roku. W ciągu 48 godzin przed wykonaniem zabiegu ESWL oznaczano morfologię krwi, wykładniki stanu zapalnego, stężenie parametrów nerkowych w surowicy (kreatynina, mocznik, cystatyna C, koagulogram. Wyliczano klirensy dla kreatyniny oraz cystatyny C. Mierzono wartości ciśnienia tętniczego. Ponownej oceny czynności nerek w oparciu o te same parametry dokonano w okresie od 1 do 5 miesięcy (średni czas 2,8 miesiąca po zabiegu. Wyniki: Średnie stężenia cystatyny C i kreatyniny oraz wartości klirensów kreatyniny i cystatyny C, mocznika, wartości ciśnienia skurczowego i rozkurczowego nie wykazały istotnych statystycznie różnic przed i po zabiegu ESWL. Stwierdzono statystycznie znamienne

Bezpieczne formy aktywności fizycznej dla kobiet w ciąży = Secure forms of physical activity for pregnant women

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Katarzyna Urtnowska

2016-05-01

4Wydział Kultury Fizycznej, Zdrowia i Turystyki, Uniwersytet Kazimierza Wielkiego w Bydgoszczy           mgr Katarzyna Urtnowska1, dr n. med. Irena Bułatowicz2, dr hab. n. med. Grzegorz Ludwikowski3, dr hab. Walery Zukow4 1Uczestnik studiów dokotranckich z zakresu Nauk o Zdrowiu; Zakład Medycyny Rozdrodu i Andrologii, Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytet Mikołaja Kopernika w Toruniu 2Katedra Fizjoterapii - Zakład Fizjoterapii Klinicznej, Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytet Mikołaja Kopernika w Toruniu 3Zakład Medycyny Rozdrodu i Andrologii, Collegium Medicum im. L. Rydygiera w Bydgoszczy Uniwersytet Mikołaja Kopernika w Toruniu 4Wydział Kultury Fizycznej, Zdrowia i Turystyki, Uniwersytet Kazimierza Wielkiego w Bydgoszczy           Słowa kluczowe: ciąża, aktywność fizyczna, sport. Keywords: pregnancy, physical activity, sport.           Streszczenie Kobieta spodziewać się dziecka w dzisiejszych czasach ma wiele możliwości podjęcia bezpiecznej formy aktywności fizycznej. Z odrobiną racjonalnego podejścia może kontynuować uprawianie ulubionego sportu, lub uczestniczyć w zajęciach przygotowanych specjalnie dla ciężarnych. Aktywność fizyczna uprawiana regularnie w trakcie ciąży jest kluczowym czynnikiem wpływającym na zdrowie i samopoczucie matki. Ćwiczenia wpływają korzystnie na stan zdrowia poprzez zmniejszenie dolegliwości bólowych kręgosłupa, ogólną poprawę lub brak pogorszenia sprawności fizycznej, zapobieganie nadmiernemu przyrostowi masy ciała i poprawę samopoczucia ciężarnej. Dodatkowym, a zarazem najważniejszym efektem jest zwiększenie wydolności fizycznej niezbędnej do porodu siłami natury i skrócenie czasu jego przebiegu oraz czasu regeneracji organizmu w połogu, a co za tym idzie, szybszy powrót do formy sprzed ciąży.     Abstract A women expect a child a child today has a lot of possibilities for secure forms of physical activity. With

The CI:Marketing interface

OpenAIRE

Wright, Sheila

2005-01-01

The potential for CI to inform and influence marketing decisions is increasing and this combination can deliver an enviable competitive advantage. Simply knowing more about competitors is not enough. It is what the firm does with that information and how it weaves it into its decision making process which makes the difference. In a large number of organisations, private or public, it is the Marketing Department which carries the responsibility for critical activities such as customer manageme...

A ciência no espaço educacional da criança: do fazer ciência à ciência do fazer

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Carolina Rodrigues de Souza

2016-05-01

Full Text Available This article aims to reflect on the possible articulations of the development of science in the education of children and their respective childhoods. While in Kindergarten and Elementary School students are, above all, children, and as such, subjects endowed with intelligence, emotions, and feelings. They are able to make observations, retain information, propose arguments, participate in discussions, and make choices that allow them to exercise free expression of theirs thoughts in many different languages. However, to ensure the effective participation of the child as a subject of today, not an intented being, it is necessary to reconsider the actions and relationships in the school environment. In this sense, this study highlights contributions on how the educational process of science can/should be thought in the process of children education. Also, we hope to provide access to scientific culture without detracting the childhoods. We highlight the possibility of using some powerful elements of science in the school environment to sharpen curiosity and improve new worldviews. Often different from the adult perspective, science in children education should emphasize issues such as the specificity of child logic, which encompasses creativity, imagination, fantasy, and desire. This article, in its theoretical nature, discusses notions such as childhood, children, and science in order to consider a type of early childhood education in which an educational routine with elements of scientific culture would enable the occurrence of childhood practice. Este artigo objetiva refletir sobre as possíveis articulações do desenvolvimento das ciências na educação das crianças e suas respectivas infâncias e parte da compreensão de que na Educação Infantil e nos primeiros anos do Ensino Fundamental, os estudantes antes de alunos são crianças, e como tais, são sujeitos completos, dotados de inteligência, emoções e sentimentos; capazes de

Complex coordinate rotation and relativistic Hylleraas-CI: helium isoelectronic series

International Nuclear Information System (INIS)

Pestka, G; Bylicki, M; Karwowski, J

2007-01-01

A combination of the Hylleraas-CI (Hy-CI) and complex coordinate rotation (CCR) methods has been applied to study the nuclear charge dependence of the eigenvalues of the Dirac-Coulomb (DC) Hamiltonian corresponding to the ground states of helium isoelectronic series atoms. It has been shown that the CCR, due to the separation of the localized states from the unphysical Brown-Ravenhall continuum, removes the instabilities of the bound-state eigenvalues observed in large-basis set Hy-CI results. The Hy-CI-CCR results are in very good agreement with the most accurate ones available in the literature. Surprisingly, the difference between the DC Hy-CI-CCR eigenvalues and the eigenvalues of the positive-energy projected no-pair Hamiltonian is equal, up to the numerical accuracy of the results, to (Zα) 3 /6π, i.e. to (Zα) 3 relativistic many-body perturbation theory contribution for electron-electron Coulomb interaction operator. An excellent agreement between the Hy-CI-CCR eigenvalues shifted by (Zα) 3 /6π and the no-pair ones confirms the very high accuracy achieved in both approaches. The numerical accuracy of the Hy-CI-CCR DC eigenvalues is estimated to eight significant figures

The maternal genes Ci-p53/p73-a and Ci-p53/p73-b regulate zygotic ZicL expression and notochord differentiation in Ciona intestinalis embryos.

Science.gov (United States)

Noda, Takeshi

2011-12-01

I isolated a Ciona intestinalis homolog of p53, Ci-p53/p73-a, in a microarray screen of rapidly degraded maternal mRNA by comparing the transcriptomes of unfertilized eggs and 32-cell stage embryos. Higher expression of the gene in eggs and lower expression in later embryonic stages were confirmed by whole-mount in situ hybridization (WISH) and quantitative reverse transcription-PCR (qRT-PCR); expression was ubiquitous in eggs and early embryos. Knockdown of Ci-p53/p73-a by injection of antisense morpholino oligonucleotides (MOs) severely perturbed gastrulation cell movements and expression of notochord marker genes. A key regulator of notochord differentiation in Ciona embryos is Brachyury (Ci-Bra), which is directly activated by a zic-like gene (Ci-ZicL). The expression of Ci-ZicL and Ci-Bra in A-line notochord precursors was downregulated in Ci-p53/p73-a knockdown embryos. Maternal expression of Ci-p53/p73-b, a homolog of Ci-p53/p73-a, was also detected. In Ci-p53/p73-b knockdown embryos, gastrulation cell movements, expression of Ci-ZicL and Ci-Bra in A-line notochord precursors, and expression of notochord marker gene at later stages were perturbed. The upstream region of Ci-ZicL contains putative p53-binding sites. Cis-regulatory analysis of Ci-ZicL showed that these sites are involved in expression of Ci-ZicL in A-line notochord precursors at the 32-cell and early gastrula stages. These results suggest that p53 genes are maternal factors that play a crucial role in A-line notochord differentiation in C. intestinalis embryos by regulating Ci-ZicL expression. Copyright © 2011 Elsevier Inc. All rights reserved.

FDG PET/CT in pediatric primary bone tumours: comparison with conventional imaging (CI) and management impact assesment

International Nuclear Information System (INIS)

Stege, Claudia; London, Kevin; Cross, Siobhan; Howman-Giles, Robert; Onikul, Ella; Graf, Nicole; Pozza, L.D.

2009-01-01

Full text: To evaluate PET/CT in pediatric primary bone tumours (PBT), the accuracy, clinical impact, prognostic indicators in predicting tumour response to therapy and determining epiphyseal involvement were compared to Cl. Methods: A retrospective review of PET/CT scans with CI was performed. Lesions were compared to a reference standard: histopathology or follow up >6 mths. Pt based analysis was performed for clinical impact. Prognostic indicators (SUYmax, tumour size) were compared to histopathology response post chemotherapy. Results: 43 pts (average 12.9 yrs) with osteosarcoma (I 8), Ewing's sarcoma (21), PNE (4) were analysed. 109 PET/CT scans with CI scans were evaluated (371 lesions). 33 lesions were discordant. Accuracy of PET/CT was higher for all lesions than CI (95% vs92%) but sensitivity was lower (79% vs 83%). Excluding lung lesions, sensitivities increased for PET/CT and CI (92% vs 89%). 9pts had PET/CT staging and follow up with histopathological evaluation post chemotherapy: 2pts poor responders, 7 good responders. Good responders had a higher SUYmax at diagnosis compared to poor responders (av 13.84 vs 7.95) but reduced more [10.5(70%) vs 3.5( 45%)]following chemotherapy. There were no false negatives for epiphyseal involvement for PET/CT and CI but one PET/CT was false positive. Conclusion: PET/CT is less sensitive in small lung lesions, but more sensitive in other areas compared to Cl. SUYmax at diagnosis is a poor predictor of response, but percent decrease post therapy was associated with therapeutic response. Change in tumour size on MR is a poor predictor of response. There is improved clinical impact with PET/CT in patient management.

Da possibilidade de uma Teoria Pura da Ciência da Informação: reflexões iniciais entre a Ciência da Informação e a Ciência do Direito

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Max Cirino de Mattos

Full Text Available O artigo discute a fragilidade epistemológica da Ciência da Informação, a partir da adoção de um termo polissêmico, como objeto científico, e a similaridade dessa situação com o contexto da criação da Teoria Pura do Direito de Hans Kelsen. Após a apresentação de algumas definições sobre o objeto da Ciência da Informação, discutem-se alguns reflexos relacionados à identidade científica e à fundamentação teórica derivadas de um objeto polissêmico. Apresenta-se uma breve introdução à Teoria Pura do Direito e algumas reflexões sobre a possibilidade de uma Teoria Pura da Ciência da Informação.

Synthesis of 5-organo-, 9-organo-, and 9,11-diorgano-nido-7,8-dicarbaundecaborate salts by a cross-combination reaction

International Nuclear Information System (INIS)

Zakharkin, L.I.; Ol'shevskaya, V.A.; Petrovskij, P.V.

2000-01-01

It has been shown for the first time that salts of 5-iodine and 9,11-diiodine-nido-7,8-dicarbaundecaborates, containing iodine atoms near polyhedron pentagonal surface boron atoms, enter cross-combination reaction with magnesium organic compounds during catalysis by palladium complexes with formation of 5-organo-, 9-organo-, and 9,11-diorgano-nido-7,8-dicarbaundecaborate salts [ru

Synthesis of C-9-14C-1,8-dihydroxy-3-carboxyanthraquinone

International Nuclear Information System (INIS)

De Witte, P.; Lemli, J.

1988-01-01

The synthesis of C-9- 14 C-rhein is reported using 14 CO 2 as a 14 C-source. After preparing 14 C-1, 8-dimethoxy-3-methylanthraquinone by a condensation reaction, the product is demethylated and the 3-methyl group converted to the corresponding 3-carboxy group. The radio-active yield of the total synthesis, starting with 1 Ci 14 CO 2 is 6,9% (6, 9 mCi); 352 mg 14 rhein is produced with a specific activity of 55,7 mCi/mmol. (author)

A ideia de ciência em Karl Marx

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Ricardo Luís Chaves Feijó

2015-12-01

ideias: a economia política clássica e o legado alemão. Em seguida, investiga-se o que seria a sua concepção particular de ciência, entendida como uma proposta de fundir esses dois legados. Avalia-se, em seguida, o caráter científico da contribuição marxiana, entendida como o fazer de uma ciência que se propõe positiva. Destarte, iremos examinar as razões que separam a tradição marxiana e o mainstream da economia atual, mostrando que a natureza peculiar de uma ciência de raízes alemãs gera dificuldades na comunicação entre uma e outra.

Application of the graphical unitary group approach to the energy second derivative for CI wave functions via the coupled perturbed CI equations

International Nuclear Information System (INIS)

Fox, D.J.

1983-10-01

Analytic derivatives of the potential energy for Self-Consistent-Field (SCF) wave functions have been developed in recent years and found to be useful tools. The first derivative for configuration interaction (CI) wave functions is also available. This work details the extension of analytic methods to energy second derivatives for CI wave functions. The principal extension required for second derivatives is evaluation of the first order change in the CI wave function with respect to a nuclear perturbation. The shape driven graphical unitary group approach (SDGUGA) direct CI program was adapted to evaluate this term via the coupled-perturbed CI equations. Several iterative schemes are compared for use in solving these equations. The pilot program makes no use of molecular symmetry but the timing results show that utilization of molecular symmetry is desirable. The principles for defining and solving a set of symmetry adapted equations are discussed. Evaluation of the second derivative also requires the solution of the second order coupled-perturbed Hartree-Fock equations to obtain the correction to the molecular orbitals due to the nuclear perturbation. This process takes a consistently higher percentage of the computation time than for the first order equations alone and a strategy for its reduction is discussed

Combustion Stratification for Naphtha from CI Combustion to PPC

KAUST Repository

Vallinayagam, R.; Vedharaj, S.; An, Yanzhao; Dawood, Alaaeldin; Izadi Najafabadi, Mohammad; Somers, Bart; Johansson, Bengt

2017-01-01

This study demonstrates the combustion stratification from conventional compression ignition (CI) combustion to partially premixed combustion (PPC). Experiments are performed in an optical CI engine at a speed of 1200 rpm for diesel and naphtha (RON

Kontrowersje w leczeniu dietetycznym otyłości

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Irena Białokoz-Kalinowska

2009-03-01

Full Text Available Otyłość jest zjawiskiem coraz częściej występującym na świecie. Szacuje się, że ponad połowę dorosłej populacji krajów uprzemysłowionych dotknęła nadwaga, a odsetek otyłości w niektórych krajach (USA, Wielka Brytania wzrasta do 30%. Ta niepokojąca tendencja obserwowana jest również w populacji dzieci i młodzieży. Epidemia otyłości rozpoczęła się w latach 80. i trwa nieprzerwanie do chwili obecnej, stając się poważnym problemem społeczno-medycznym współczesnego świata. Przyczyny tego zjawiska są złożone i wynikają z uwarunkowań biologicznych i środowiskowych, w szczególności z niedostatecznej codziennej aktywności fizycznej oraz złych nawyków żywieniowych. Do tej pory nie udało się wypracować w pełni efektywnej strategii leczenia otyłości. Promocja zdrowego stylu życia oraz właściwych nawyków żywieniowych adresowana do całej populacji stanowi podstawę prewencji i leczenia otyłości. Powszechnie stosowane różnego rodzaju diety odchudzające zawierają często sprzeczne zalecenia. Istniejące kontrowersje utrudniają wybór skutecznej diety w celu redukcji masy ciała, a ich mnogość i różnorodność wprowadzają swoisty chaos informacyjny. Efekty wielu diet są krótkotrwałe i obarczone efektem jo-jo. W wielu przypadkach brak jest jakichkolwiek przesłanek naukowych uzasadniających dane postępowanie dietetyczne. Właśnie dlatego wciąż istnieje potrzeba prowadzenia dalszych badań naukowych umożliwiających w sposób obiektywny ocenę skuteczności dietetycznych metod leczenia otyłości. W niniejszej pracy autorzy przedstawiają spotykane w praktyce różne dietetyczne podejścia do problemu otyłości, wskazując na ich efektywność i naukowe uzasadnienie.

Development and Analysis of Original UNIFAC-CI and Modified UNIFAC-CI Models for Prediction of VLE and SLE Systems

DEFF Research Database (Denmark)

Mustaffa, Azizul Azri; Kontogeorgis, Georgios; Kang, Jeong Won

approach that is able to extend the application range of property models has been developed for mixture properties. This so-called GCPlus approach is a hybrid model which combines GC and valence connectivity indices (CI). The main idea is the use of CI to describe the molecular fragmentation that relates...... parameters are checked using a quality assessment algorithm which combines four widely used consistency tests (Herington, Van Ness, Point/Differential and Infinite Dilution tests) and also a check on the consistencies of the data with the pure component vapor pressures. The overall quality factors, QVLE...

Filosofia da ciência, ensino de ciências e psicanálise: Explorando analogias

Directory of Open Access Journals (Sweden)

Alberto Villani

2005-06-01

Full Text Available Desenvolveremos um esquema referente às atitudes dos cientistas frente ao conhecimento científico, tendo como referência, de um lado, o debate entre Kuhn, Pepper, Lakatos e Feyerabend e, de outro, conceitos da psicanálise lacaniana. Em seguida, exploraremos esse esquema com uma analogia que nos permitirá elaborar novas interpretações para a educação em Ciências.

Antioxidant properties of selected culinary spices / Antyoksydacyjne właściwości wybranych przypraw

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Słowianek Marta

2016-03-01

Full Text Available Wstęp: Przyprawy dodawane do żywności wzbogacają jej walory smakowe i zapachowe, niektóre z nich mogą także wydłużać jej czas przechowywania dzięki obecności związków o aktywności przeciwutleniającej. Cel: Celem pracy było zbadanie 28 przypraw dostępnych na rynku pod kątem całkowitej zawartości polifenoli i aktywności przeciwutleniającej. Metody: Do oceny całkowitej zawartości związków fenolowych zastosowano metodę Folina- Ciocalteau. Aktywność antyoksydacyjną ekstraktów oznaczono metodą z użyciem rodnika DPPH. Wyniki: Otrzymane wyniki wykazują, że większość analizowanych przypraw jest bogata w związki fenolowe i posiada wysoką aktywność antyoksydacyjną. Całkowita zawartość polifenoli w przyprawach oscylowała od 0,9 do 155,1 mg GAE/g z najniższą wartością odnotowaną dla sezamu i najwyższą dla cynamonu. Zdolność do wygaszania rodnika DPPH wyrażona w procentach była zróżnicowana i wahała się w zakresie od 4,1% dla sezamu do 94,9% dla goździków. Odnotowano umiarkowaną korelację (r=0,63, p<0,05 pomiędzy aktywnością antyoksydacyjną i zawartością polifenoli ogółem, co dowodzi, że związki fenolowe są ważnymi, antyoksydacyjnymi składnikami w badanych przyprawach. Wnioski: Prowadzone badania wykazują, że wiele przypraw może służyć jako naturalne konserwanty żywności i jednocześnie ma korzystny wpływ na nasze zdrowie.

Characteristics and determinants of music appreciation in adult CI users.

Science.gov (United States)

Philips, Birgit; Vinck, Bart; De Vel, Eddy; Maes, Leen; D'Haenens, Wendy; Keppler, Hannah; Dhooge, Ingeborg

2012-03-01

The main objective of this study was to assess the associations between self-reported listening habits and perception of music and speech perception outcomes in quiet and noise for both unilateral cochlear implant (CI) users and bimodal (CI in one ear, hearing aid in contra-lateral ear) users. Information concerning music appreciation was gathered by means of a newly developed questionnaire. Moreover, audiological data (pure-tone audiometry, speech tests in noise and quiet) were gathered and the relationship between speech perception and music appreciation is studied. Bimodal users enjoy listening to music more in comparison with unilateral CI users. Also, music training within rehabilitation is still uncommon, while CI recipients believe that music training might be helpful to maximize their potential with current CI technology. Music training should not be exclusively reserved for the good speech performers. Therefore, a music training program (MTP) that consists of different difficulty levels should be developed. Hopefully, early implementation of MTP in rehabilitation programs can enable adult CI users to enjoy and appreciate music and to maximize their potential with commercially available technology. Furthermore, because bimodal users consider the bimodal stimulation to be the most enjoyable way to listen to music, CI users with residual hearing in the contra-lateral ear should be encouraged to continue wearing their hearing aid in that ear.

A ciência e a tecnologia n’A Capital: da página de fait-divers à página de ciência

OpenAIRE

Fonseca, Rui Brito

2009-01-01

Durante muito tempo, a ciência e a tecnologia foram olhadas, pela população em geral, como mais um tema de entretenimento e curiosidade, a par de outros. Para a imprensa portuguesa, mormente a imprensa de cariz “popular”, a ciência e a tecnologia também foram durante algum tempo olhadas como um assunto de entretenimento e curiosidade. Partindo da análise, quantitativa e qualitativa, de cerca de 2000 artigos sobre ciência e tecnologia, publicados no jornal diário, pago e de c...

Max Weber e a objetividade do conhecimento nas ciências da cultura: um breve guia para o texto A ‘Objetividade’ do Conhecimento na Ciência Social e na Ciência Política (1904

Directory of Open Access Journals (Sweden)

Jean Henrique Costa

2011-05-01

Full Text Available

O presente artigo objetiva discutir o sentido da objetividade do conhecimento empírico-social na obra de Max Weber, especificamente no texto “A ‘Objetividade’ do Conhecimento na Ciência Social e na Ciência Política”, de 1904. Discute-se, no primeiro momento, a distinção entre conhecimento empírico e juízo de valor; no segundo momento, faz-se uma rápida crítica às idéias de “lei” e “conexão regular” nas ciências sociais para, em seguida, na terceira parte, discutir a estrutura da formação dos conceitos típico-ideais como recursos metodológicos, nos quais, para Weber, expressam a possibilidade da validade objetiva do conhecimento nas ciências da cultura.

Cinema, ciência e percepção.

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Márcio Barreto

Full Text Available Resumo O cinema invoca a questão dos limites da percepção humana, pois modula o tempo em imagens tão reais quanto artificiais, revelando algo mais próximo de uma nova dimensão da realidade do que de sua representação. No início do século XX, a ciência modifica o real percebido através das lentes dos microscópios e das teorias da física moderna; o parentesco entre cinema e ciência está principalmente naquilo que excede o campo perceptivo e é explorado neste artigo para mostrar como a tensão entre o caráter estático da fotografia e a fluidez fugitiva do tempo revela a ciência sem seus estereótipos habituais.

Skinner: sobre ciência e comportamento humano

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Angelo Augusto Silva Sampaio

Full Text Available Atualmente, não se pode pensar no estudo do comportamento humano sem considerar a abordagem científica a este objeto: o campo da Psicologia científica. Esse campo é disputado por diversos enfoques teóricos que divergem quanto ao modo como definem ciência e comportamento humano. A abordagem de B. F. Skinner foi bastante proeminente no século XX, mas ainda continua a ser mal-entendida. Partindo do desenvolvimento histórico de sua obra, o presente texto visa a iluminar alguns aspectos relacionados às noções de ciência e comportamento humano desse autor e ressaltar as transformações por que passaram. Analisam-se três tópicos da obra de Skinner: seu período inicial (de 1930 a cerca de 1938, a obra "Ciência e Comportamento Humano" de 1953, e as influências da Biologia. São enfatizados aspectos relevantes da sua teorização sobre o tema: busca por relações funcionais, ênfase nos dados empíricos, operacionismo, externalismo, multideterminação do comportamento, experimentalismo, previsão e controle, ética.

Por uma ciência do riso e da sabedoria

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Paula Corrêa Henning

2010-06-01

Full Text Available

O artigo busca problematizar a história das ciências, especialmente o ethos da Modernidade e Pós-modernidade. Para isso, utiliza autores que se anteciparam à Pós-modernidade como Friedrich Nietzsche e Michel Foucault. Na esteira dessa discussão busca uma problematização acerca da Ciência nos rastros da Modernidade e algumas fissuras e fragilidades produzidas na ciência num cenário contemporâneo. Apresenta ainda alguns discursos midiáticos acerca de propagandas televisivas que trazem o discurso científico como legítimo e inabalável. Traz para o campo de discussão uma ciência alegre, como aprendemos com Nietzsche ou prosaica por vezes, anunciando o riso e a sabedoria na produção do conhecimento científico.

Technician-Supported Remote Interrogation of CIEDs: Initial Use in US Emergency Departments and Perioperative Areas.

Science.gov (United States)

Ahmed, Imdad; Patel, Amisha S; Balgaard, Timothy J; Rosenfeld, Lynda E

2016-03-01

Interrogation/interpretation of cardiac implantable electronic devices (CIEDs) is frequently required in the emergency department (ED) or perioperative areas (OR) where resources to do this are often not available. CareLink Express (CLE; Medtronic, plc, Mounds View, MN, USA) is a technician-supported real-time remote interrogation system for Medtronic CIEDs. Using data from 136 US locations, this retrospective study was designed to assess CLE efficiency compared to traditional device management, and examine its findings. All 7,044 US CLE transmissions from the ED and OR (January 2012-October 2014) were compared to 217 traditional requests where CIED interrogations/interpretations were performed by calling industry representatives to these sites. CLE reduced the time to device interrogation/interpretation by 78%: 100 ± 140-22 ± 14 minutes, P < 0.0001, improving response time and consistency; ED: 82 ± 103-23 ± 18 minutes, P, ≤ 0.01; OR: 127 ± 181-17 ± 10 minutes, P < 0.0001. Actionable events (AE) (arrhythmia, device/lead abnormalities) were infrequent: 9.1% overall (ED: 9.9%; OR: 4.1%). Only 6.5% of patients with syncope/presyncope and 13.6% with a perceived shock had AE. AEs were more common in those with suspected device problems (30.4%) or audible alerts (52.6%). They were more likely in patients not enrolled in long-term remote monitoring (23.9% vs 8.2%, P < 0.0001) and in those with older CIED systems (7.4% in year 1 vs 31.0% after 10 years). The many patients with CIEDs, and the ability to quickly identify the minority with high-risk AE from the no/low-risk majority, strongly support CLE use in the ED and OR, sites which are expensive and prioritize efficiency. © 2015 Wiley Periodicals, Inc.

Salt intake and dietary sources of salt on weekdays and weekend days in Australian adults.

Science.gov (United States)

Nowson, Caryl; Lim, Karen; Land, Mary-Ann; Webster, Jacqui; Shaw, Jonathan E; Chalmers, John; Flood, Victoria; Woodward, Mark; Grimes, Carley

2018-02-01

To assess if there is a difference in salt intake (24 h urine collection and dietary recall) and dietary sources of salt (Na) on weekdays and weekend days. A cross-sectional study of adults who provided one 24 h urine collection and one telephone-administered 24 h dietary recall. Community-dwelling adults living in the State of Victoria, Australia. Adults (n 598) who participated in a health survey (53·5 % women; mean age 57·1 (95 % CI 56·2, 58·1) years). Mean (95 % CI) salt intake (dietary recall) was 6·8 (6·6, 7·1) g/d and 24 h urinary salt excretion was 8·1 (7·8, 8·3) g/d. Mean dietary and 24 h urinary salt (age-adjusted) were 0·9 (0·1, 1·6) g/d (P=0·024) and 0·8 (0·3, 1·6) g/d (P=0·0017), respectively, higher at weekends compared with weekdays. There was an indication of a greater energy intake at weekends (+0·6 (0·02, 1·2) MJ/d, P=0·06), but no difference in Na density (weekday: 291 (279, 304) mg/MJ; weekend: 304 (281, 327) mg/MJ; P=0·360). Cereals/cereal products and dishes, meat, poultry, milk products and gravy/sauces accounted for 71 % of dietary Na. Mean salt intake (24 h urine collection) was more than 60 % above the recommended level of 5 g salt/d and 8-14 % more salt was consumed at weekends than on weekdays. Substantial reductions in the Na content of staple foods, processed meat, sauces, mixed dishes (e.g. pasta), convenience and takeaway foods are required to achieve a significant consistent reduction in population salt intake throughout the week.

Natureza e ciências sociais

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Gloria Maria Vargas

2003-12-01

Full Text Available A construção do sentido do termo natureza abrange diferentes áreas do conhecimento e tem sido objeto de reflexão tanto das ciências naturais quanto sociais. Nos desdobramentos do conhecimento produzido sobre esta temática existem diversas abordagens que, da perspectiva das ciências sociais, podem ser identificadas. O propósito deste artigo é considerar algumas dessas abordagens e relacioná-las com as novas práticas sociais que determinam formas de intervenção inéditas sobre a natureza, e que colocam questões para estas ciências, enquanto produtoras de conhecimento sobre o tema. De igual forma, explicita-se a substituição deste termo pelo de ambiente e, posteriormente, o aparecimento do desenvolvimento sustentável, como parte do cabedal conceitual com que a problemática em torno das relações naturezasociedade é abordada nas ciências sociais.La construcción del sentido del término naturaleza abarca diferentes áreas del conocimiento y ha sido objeto de reflexión tanto de las ciencias naturales como sociales. Los desdoblamientos del conocimiento producido sobre este tema muestran que existen diversos abordajes que pueden ser identificados desde la perspectiva de las ciencias sociales. El objetivo de este artículo es considerar algunos de esos abordajes y relacionarlos con las nuevas prácticas sociales que determinan formas de intervención inéditas sobre la naturaleza y que sugieren cuestionamientos para estas ciencias, como productoras de conocimiento sobre este tema. De igual manera, se explicita la substitución de este término por el de ambiente e, posteriormente, el aparecimiento del término desarrollo sostenible como parte del acervo conceptual con que es abordada la problemática alrededor de las relaciones naturaleza-sociedad en las ciencias sociales.The construction of the term nature involves different areas of knowledge and has been the object of inquiry of both natural and social sciences. The knowledge

Pomiar wiarygodności internetowych serwisów handlowych.

OpenAIRE

Garnik, Igor; Basińska, Beata

2011-01-01

Rozwój handlu internetowego jest odpowiedzią na zapotrzebowanie klientów na tę formę dystrybucji towarów i usług. Z tego powodu, zarządzanie witryną sklepu internetowego, w celu zwiększenia jej wiarygodności, a co za tym idzie – konkurencyjności, jest ważnym zadaniem stojącym przed podmiotami prowadzącymi działalność gospodarczą w sieci. Celem niniejszej pracy było zaproponowanie nowej metody oceny wiarygodności serwisów WWW. Badanie przeprowadzono w grupie 225 osób (83% doświadczonych i 17% ...

Using the Web for Competitive Intelligence (CI) Gathering

Science.gov (United States)

Rocker, JoAnne; Roncaglia, George

2002-01-01

Businesses use the Internet as a way to communicate company information as a way of engaging their customers. As the use of the Web for business transactions and advertising grows, so too, does the amount of useful information for practitioners of competitive intelligence (CI). CI is the legal and ethical practice of information gathering about competitors and the marketplace. Information sources like company webpages, online newspapers and news organizations, electronic journal articles and reports, and Internet search engines allow CI practitioners analyze company strengths and weaknesses for their customers. More company and marketplace information than ever is available on the Internet and a lot of it is free. Companies should view the Web not only as a business tool but also as a source of competitive intelligence. In a highly competitive marketplace can any organization afford to ignore information about the other players and customers in that same marketplace?

Wrap it in rap! - Music Making with Adolescent CI Users

DEFF Research Database (Denmark)

Petersen, Bjørn; Sørensen, Stine Derdau; Pedersen, Ellen Raben

2015-01-01

The purpose of this study was to examine 1) the potential effects of an intensive musical ear training program on the perception of music and speech in prelingually hearing impaired adolescent cochlear implant (CI) users and 2) these adolescents’ music engagement. Eleven adolescent CI users parti...... and repetitive focus on language, articulation, rhythm and rhyme and might even represent a possible form of artistic expression for some of the young CI users....

Empiryczna weryfikacja hipotezy o przenośności modelu Altmana na warunki polskiej gospodarki oraz uniwersalności sektorowej modeli

Directory of Open Access Journals (Sweden)

Tomasz Iwanowicz

2018-03-01

Full Text Available Celem artykułu jest próba udzielenia odpowiedzi na pytanie, czy istnieje uzasadnienie dla mechanicznego przenoszenia modelu Altmana na warunki polskiej gospodarki oraz sprawdzenie, czy wśród testowanych modeli istnieje model wykazujący dla każdego typu przedsiębiorstwa (przemysłowe, handlowe, usługo- we najwyższą skuteczność i najlepsze wartości zastosowanych metod porównawczych. W artykule porównano trzynaście testowanych modeli używając macierzy klasyfikacji, ilorazu szans, krzywej kon- centracji CAP i wskaźnika dokładności Giniego, będących metodami oceny sprawności, oraz wskaźnika Briera będącego metodą oceny modeli z punktu widzenia kryterium kalibracji. Badania zostały przepro- wadzone na bazie 439 sprawozdań finansowych opublikowanych przez 139 spółek kapitałowych zarejestrowanych w warszawskich sądach okręgowych i rejonowych (w tym 79 spółek, które w rzeczywistości ogłosiły upadłość. Przeprowadzone badania obaliły mit o przenośności modelu Altmana na warunki polskiej gospodarki oraz uniwersalności sektorowej modeli. Wykazano, że sprawność modeli różni się dla spółek produkcyjnych, handlowych i usługowych oraz określono te sprawności. Ponadto udowodniono, że istnieją modele dyskryminacyjne różniące się zestawem zmiennych oraz współczynnikami wagowymi, które wykazują zbliżone skuteczności predykcyjne. The purpose of this paper is to answer the question about the validity of mechanical transfer of the Alt- man model to Polish economy and to check if among the tested models there is a model with the highest efficiency and best outcomes for the used comparative methods for each type of enterprise (manufactur- ing, trading, service. Thirteen tested models were compared using the classification matrix, odds ratio, CAP concentration curve and Gini accuracy index, which are efficiency evaluation methods, as well as using the Brier index, which is a method of evaluating models

Kierunki zmiansprawozdawczości finansowej

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Zbigniew Luty

2010-05-01

Full Text Available W artykule wskazano na możliwe kierunki zmian w sprawozdawczości finansowej w najbliższych latach. Wymieńmy najważniejsze: 1 bazą jest informacja oparta na dokumentacji księgowej w ujęciu historycznym, 2 sprawozdania celowe (dedykowane, 3 informacja finansowa jako towar na specyficznym rynku sprawozdań, 4 prawo bilansowe tworzone z minimalnym wpływem lobbingu inwestorów.

Transseksualizm – pytania i wątpliwości

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Magdalena Radko

2012-06-01

Full Text Available Wiek dojrzewania jest czasem określania własnej tożsamości, odkrywania pragnień, dążeń, również w sferze sek‑ sualności. Poszukiwanie siebie, własnej orientacji seksualnej, znajdowanie pierwszych obiektów pożądania jest dla adolescenta nowym, ważnym przeżyciem, wyzwalającym silne emocje. Czasami jednak młody człowiek staje wo‑ bec dużych trudności, bowiem to, co odkrywa w sobie, nie znajduje umocowania w społecznych normach, nie jest akceptowane przez rodzinę i otoczenie, a w związku z tym dla samego adolescenta staje się ciężarem trudnym do uniesienia. Konsekwencją nieradzenia sobie z własną seksualnością, jej odbiorem rodzinnym lub społecznym mogą być zaburzenia depresyjne, lękowe, zaburzenia odżywiania oraz różnorodne formy autoagresji. W obliczu wysokie‑ go ryzyka występowania zaburzeń psychicznych u osób w wieku rozwojowym, u których seksualność kształtuje się w sposób odmienny, należy rozważać szerokie spektrum czynników mogących determinować takie, a nie inne oblicze seksualności. Intencją autorów pracy było przedstawienie, w oparciu o przypadek kliniczny, historii człowieka odkry‑ wającego swoją tożsamość płciową, biorąc pod uwagę zarówno osobnicze uwarunkowania, przebyte zdarzenia trau‑ matyczne, jak i kontekst rodzinny pacjenta oraz konsekwencje procesu coming out. Autorzy starali się zwrócić uwagę na złożoność i wielostopniowość procesu ujawniania się, który stał się możliwy dopiero po zapewnieniu adolescen‑ towi zrozumienia, wsparcia i akceptacji. Tym samym ukazano kluczową rolę środowiska, które może sprzyjać pro‑ cesowi odkrywania się i umożliwić go lub przeciwnie – utrudnić czy też całkowicie go zablokować. Transseksualizm w różnych środowiskach budzi sporo kontrowersji, pytań i wątpliwości. Historia hospitalizowanego pacjenta obrazu‑ je złożoność problemów, z którymi zmagają się osoby z zaburzeniami tożsamości

Między pamięcią a zapomnieniem Shoah. Problem estetycznej neutralizacji przeszłości w myśleniu historycznym Saula Friedländera

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Sawicki, Maciej

2015-06-01

Full Text Available W tekstach Saula Friedländera problem indywidualnej pamięci Shoahstanowił jedną z głównych granic dla dyskursu. Punktem krytycznym jego refleksji nad pamięcią stała się kwestia społecznego myślenia zbawczego, które stanowiło reakcję obronną wobec katastrofy. Fenomen ten ujawnił się szczególnie wyraźnie w publicznej formie pamięci, która z jednej strony domagała się prostoty i jasnej interpretacji, jako że jej zadaniem było oswojenie niekoherencji, wyeliminowanie bólu oraz rozbudzenie nadziei u współczesnych; z drugiej strony indywidualna pamięć głęboka ocalałych – nie znająca zasad – nie godziła się na formę pamięci publicznej, mimo że nie była w stanie jej się oprzeć. Według Friedländera ekspansja pamięci publicznej i zanikanie pamięci indywidualnej sprawia, iż "pamięć Shoah prawdopodobnie nie ucieknie przed całkowitą rytualizacją"1. W swoich rozważaniach częstokroć zwracał on uwagę na to, że sztuka nie może przeciwdziałać oswajaniu grozy, ponieważ musi wyrażać indywidualną pamięć przeszłości w pewnych prostych formach. Oprócz tego problematyczny stał się fakt, że same kategorie sztuki po Holokauście zostały zawładnięte przez przemysł kulturowy i politykę, przez co problem pamięci stał się środkiem przetargowym dla innych celów. Nawiązując za Friedländerem do aktualnego impasu wobec różnych oswajających mechanizmów pamięci, spróbuję poddać pod rozwagę kwestię granic i możliwości w tworzeniu estetycznego pomostu między teraźniejszością a przeszłością.

Regression Analysis to Identify Factors Associated with Household Salt Iodine Content at the Sub-National Level in Bangladesh, India, Ghana and Senegal

Science.gov (United States)

Knowles, Jacky; Kupka, Roland; Dumble, Sam; Garrett, Greg S.; Pandav, Chandrakant S.; Yadav, Kapil; Nahar, Baitun; Touré, Ndeye Khady; Amoaful, Esi Foriwa; Gorstein, Jonathan

2018-01-01

Regression analyses of data from stratified, cluster sample, household iodine surveys in Bangladesh, India, Ghana and Senegal were conducted to identify factors associated with household access to adequately iodised salt. For all countries, in single variable analyses, household salt iodine was significantly different (p < 0.05) between strata (geographic areas with representative data, defined by survey design), and significantly higher (p < 0.05) among households: with better living standard scores, where the respondent knew about iodised salt and/or looked for iodised salt at purchase, using salt bought in a sealed package, or using refined grain salt. Other country-level associations were also found. Multiple variable analyses showed a significant association between salt iodine and strata (p < 0.001) in India, Ghana and Senegal and that salt grain type was significantly associated with estimated iodine content in all countries (p < 0.001). Salt iodine relative to the reference (coarse salt) ranged from 1.3 (95% CI 1.2, 1.5) times higher for fine salt in Senegal to 3.6 (95% CI 2.6, 4.9) times higher for washed and 6.5 (95% CI 4.9, 8.8) times higher for refined salt in India. Sub-national data are required to monitor equity of access to adequately iodised salt. Improving household access to refined iodised salt in sealed packaging, would improve iodine intake from household salt in all four countries in this analysis, particularly in areas where there is significant small-scale salt production. PMID:29671774

Nauczanie sprawności komunikacyjnych w grupach ekonomicznych

OpenAIRE

Wielkiewicz-Jałmużna, Dorota

2013-01-01

Celem nauczania języka polskiego w grupach ekonomicznych jest przede wszystkim rozwijanie kompetencji uczących się. Kluczowe znaczenie mają umiejętności receptywne czyli rozumienie ze słuchu i czytanie. Istotne znaczenie ma również nauczanie sprawności produktywnych to jest mówienia i pisania. Kolejnymi sprawnościami językowymi, które uczniowie zdobywają pod nadzorem nauczyciela są: umiejętność interakcji i mediacji.

Wpływ aktywności fizycznej w okresie ciąży na przebieg porodu = The influence of physical activity during pregnancy on childbirth

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AGNIESZKA KONSTANCJA PAWŁOWSKA-MUC

2015-09-01

3 Ośrodek Kształcenia Podyplomowego Pielęgniarek i Położnych Radomski Szpital Specjalistyczny im. dr Tytusa Chałubińskiego w Radomiu, ul. Lekarska 4   Adres do korespondencji Grażyna Stadnicka Samodzielna Pracownia Umiejętności Położniczych, Wydział Nauk o Zdrowiu, Uniwersytet Medyczny 10-081 Lublin, ul. Staszica 4/6; e-mail:grazyna.stadnicka@umlub.pl   Streszczenie Aktywność fizyczna w czasie ciąży poprawia ogólną kondycję fizyczną i zapobiega dolegliwościom tego okresu. Celem pacy była ocena profilu społeczno-demograficznego kobiet rodzących oraz wpływu aktywności fizycznej w okresie ciąży na przebieg porodu. Materiał i metoda. Badania przeprowadzono wśród 150 rodzących. Narzędzie badawcze stanowiła ankieta własnego autorstwa, skala Borga oraz skala oceny bólu VAS. Wyniki. Badane były w wieku 19-41 lat,  średnia wieku wynosiła 28.7±5.3  lat. Najczęściej podejmowaną przez respondentki aktywnością fizyczną był spacer (n=29; 38.15%, fitness (n=21; 27.63%, joge (n=14; 18.42%, pilates (n=25; 32.89%.Korzystanie z aktywności ruchowej przez kobiety w ciąży było zależne od: wykształcenia (p=0.031, miejsca zamieszkania (p=0.13, statusu zawodowego (0.004 oraz wieku (p=0.042 badanych. Aktywności fizyczna w okresie ciąży miała znamienny statystycznie wpływ na sposób ukończenia ciąży (p=0.024 i wystąpienie samoistnej czynności skurczowej (p=0.001 oraz  bliski istotności statystycznej wpływ na częstość uszkodzenia krocza podczas porodu (0.049. Wnioski. Aktywność fizyczna podczas ciąży nie ma wpływu na częstotliwość okołoporodowych urazów kanału rodnego, w tym nacinania krocza. Natomiast warunkuje wystąpienie samoistnych skurczów porodowych, lepszą tolerancję bólu i wysiłku podczas porodu oraz zmniejsza liczbę cięć cesarskich.   Słowa kluczowe: ciąża, aktywność fizyczna, poród.   Abstract Physical activity during pregnancy, which improves overall physical condition and prevents

CiPA: Ongoing testing, future qualification procedures, and pending issues.

Science.gov (United States)

Cavero, Icilio; Holzgrefe, Henry

2015-01-01

The comprehensive in vitro proarrhythmia assay (CiPA) is a nonclinical, mechanism-based paradigm for assessing drug proarrhythmic liability. The first CiPA assay determines effects on cloned human cardiac ion channels. The second investigates whether the latter study-generated metrics engender proarrhythmic markers on a computationally reconstructed human ventricular action potential. The third evaluates conclusions from, and searches possibly missed effects by in silico analysis, in human stem cell-derived cardiomyocytes (hSC-CMs). CiPA ad hoc Expert-Working Groups have proposed patch clamp protocols for seven cardiac ion channels, a modified O'Hara-Rudy model for in silico analysis, detailed procedures for field (MEA) and action potential (VSD) measurements in hSC-CMs, and 29 reference drugs for CiPA assay testing and validation. CiPA adoption as drug development tool for identifying electrophysiological mechanisms conferring proarrhythmic liability to candidate drugs is a complex, multi-functional task requiring significant time, reflection, and efforts to be fully achieved. Copyright © 2015 Elsevier Inc. All rights reserved.

Kuhn e as ciências sociais

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Jesus de Paula Assis

1993-12-01

Full Text Available No texto, são expostos os motivos básicos pelos quais o vocabulário emprestado de Thomas Kuhn - notadamente o termo paradigma - e o modelo de desenvolvimento científico exposto pelo autor em seu A estrutura das revoluções científicas foram tomados de empréstimo em textos que discutem a epistemologia das ciências sociais. A conclusão é que as supostas aplicações do modelo kuhniano às ciências sociais se baseiam em leitura que não encontra qualquer apoio no autor e, principalmente, obscurecem as implicações mais amplas de sua obra.The article shows for what reasons the vocabulary and the model for scientific growth of Thomas Kuhn were borrowed by epistemologists of the social sciences. The conclusion is that the texts produced in this vein are based in a shallow understanding of the author's main implications.

Music Perception and Appraisal: Cochlear Implant Users and Simulated CI Listening

Science.gov (United States)

Wright, Rose; Uchanski, Rosalie M.

2012-01-01

Background The inability to hear music well may contribute to decreased quality of life for cochlear implant (CI) users. Researchers have reported recently on the generally poor ability of CI users’ to perceive music, and a few researchers have reported on the enjoyment of music by CI users. However, the relation between music perception skills and music enjoyment is much less explored. Only one study has attempted to predict CI users’ enjoyment and perception of music from the users’ demographic variables and other perceptual skills (Gfeller et al., 2008). Gfeller’s results yielded different predictive relationships for music perception and music enjoyment, and the relationships were weak, at best. Purpose The first goal of this study is to clarify the nature and relationship between music perception skills and musical enjoyment for CI users, by employing a battery of music tests. The second goal is to determine whether normal hearing (NH) subjects, listening with a CI-simulation, can be used as a model to represent actual CI users for either music enjoyment ratings or music perception tasks. Research Design A prospective, cross-sectional observational study. Original music stimuli (unprocessed) were presented to CI users, and music stimuli processed with CI-simulation software were presented to twenty NH listeners (CIsim). As a control, original music stimuli were also presented to five other NH listeners. All listeners appraised twenty-four musical excerpts, performed music perception tests, and filled out a musical background questionnaire. Music perception tests were the Appreciation of Music in Cochlear Implantees (AMICI), Montreal Battery for Evaluation of Amusia (MBEA), Melodic Contour Identification (MCI), and University of Washington Clinical Assessment of Music Perception (UW-CAMP). Study Sample Twenty-five NH adults (22 – 56 years old), recruited from the local and research communities, participated in the study. Ten adult CI users (46 – 80

Semiempirical UNO-CAS and UNO-CI: method and applications in nanoelectronics.

Science.gov (United States)

Dral, Pavlo O; Clark, Timothy

2011-10-20

Unrestricted Natural Orbital-Complete Active Space Configuration Interaction, abbreviated as UNO-CAS, has been implemented for NDDO-based semiempirical molecular-orbital (MO) theory. A computationally more economic technique, UNO-CIS, in which we use a configuration interaction (CI) calculation with only single excitations (CIS) to calculate excited states, has also been implemented and tested. The class of techniques in which unrestricted natural orbitals (UNOs) are used as the reference for CI calculations is denoted UNO-CI. Semiempirical UNO-CI gives good results for the optical band gaps of organic semiconductors such as polyynes and polyacenes, which are promising materials for nanoelectronics. The results of these semiempirical UNO-CI techniques are generally in better agreement with experiment than those obtained with the corresponding conventional semiempirical CI methods and comparable to or better than those obtained with far more computationally expensive methods such as time-dependent density-functional theory. We also show that symmetry breaking in semiempirical UHF calculations is very useful for predicting the diradical character of organic compounds in the singlet spin state.

Bezpieczne formy aktywności fizycznej dla kobiet w ciąży = Secure forms of physical activity for pregnant women

OpenAIRE

Urtnowska, Katarzyna; Bułatowicz, Irena; Ludwikowski, Grzegorz; Zukow, Walery

2016-01-01

Urtnowska Katarzyna, Bułatowicz Irena, Ludwikowski Grzegorz, Zukow Walery. Bezpieczne formy aktywności fizycznej dla kobiet w ciąży = Secure forms of physical activity for pregnant women. Journal of Education, Health and Sport. 2016;6(5):291-297. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.51894 http://ojs.ukw.edu.pl/index.php/johs/article/view/3526 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 755 (23...

Wpływ regularnej aktywności fizycznej na skład ciała i ciśnienie tętnicze dzieci ze szkoły sportowej

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Małgorzata Stańczyk

2013-06-01

Full Text Available Wstęp: Trening fizyczny uważany jest za czynnik wpływający na parametry antropometryczne i ciśnienie tęt‑ nicze. Twierdzi się, że osoby regularnie ćwiczące mają lepsze wskaźniki składu ciała oraz niższe wartości ciśnienia tętniczego krwi w porównaniu z osobami nieuprawiającymi sportu. Cel: Ocena wpływu regularnej rocznej aktywności fizycznej prowadzonej w szkole sportowej na skład ciała oraz wartości ciśnienia tętnicze‑ go u dzieci 14-letnich (II klasa gimnazjum. Materiał i metodyka: W badaniu wzięło udział 25 dzieci z gim‑ nazjum sportowego. Dzieci badano dwukrotnie w odstępie 12 miesięcy. Analizie poddano zmianę parame‑ trów antropometrycznych, składu ciała metodą impedancji bioelektrycznej oraz wartości ciśnienia krwi. Wyniki: W całej grupie zaobserwowano wzrost wartości centylowych ciśnienia skurczowego krwi (p < 0,05, przede wszystkim u chłopców. W zakresie ciśnienia rozkurczowego nie zanotowano istotnych różnic. Skład ciała zmienił się niekorzystnie u wszystkich badanych – wzrósł udział tłuszczu (13% vs 20%, p < 0,05, a przy‑ rost masy tłuszczowej był wyższy u dziewczynek (6% vs 3%, p < 0,05. Centyl BMI istotnie statystycznie wzrósł w grupie dziewczynek (37 vs 49, p < 0,05, u chłopców nie uległ zmianie. Wnioski: Aktywność fizyczna proponowana przez szkołę sportową nie poprawia stanu odżywienia 13–14-letnich dziewcząt i chłopców, u których obserwuje się istotne zwiększenie w organizmie zawartości tkanki tłuszczowej. Szkolna aktywność fizyczna nie powoduje obniżenia ciśnienia tętniczego wśród młodzieży w wieku 13–14 lat w odniesieniu do norm wiekowych. W zakresie ciśnienia skurczowego w grupie chłopców zaobserwowano nawet wyższe wartości centylowe.

Ciências da Religião numa sociedade multicultural

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Wolfgang Gruen

2009-05-01

Full Text Available Texto originalmente apresentado como aula inaugural do Programa de Pós-graduação em Ciências da Religião da PUC Minas. Trata da epistemologia e dos desafios da investigação em Ciências da Religião. Partindo do problema de base da religiosidade na Educação, do fenômeno religioso e sua dimensão profunda, o artigo segue uma densa investigação sobre os limites e horizontes das Ciências da Religião.Palavras-chave: Ciências da Religião; Religião; Religiosidade; Educação; Ensino religioso.ABSTRACTThis text was originally presented as the opening class of the Postgraduate Programme in Sciences of Religion of PUC Minas. It concerns the epistemology and challenges of investigation in Sciences of Religion. Starting from the fundamental question of religiosity in Education, of the religious phenomenon and its deep dimension, the article embarks on a close investigation into the limits and horizons of the Sciences of Religion.Key words: Sciences of religions; Religion; Religiosity; Education; Religious teaching.

The Ciona intestinalis immune-related galectin genes (CiLgals-a and CiLgals-b) are expressed by the gastric epithelium.

Science.gov (United States)

Parrinello, Daniela; Sanfratello, Maria Antonietta; Vizzini, Aiti; Testasecca, Lelia; Parrinello, Nicolò; Cammarata, Matteo

2017-03-01

The transcription of two Ciona intestinalis galectin genes (CiLgals-a and CiLgals-b) is uparegulated by LPS in the pharynxis (hemocytes, vessel epithelium, endostilar zones) which is retained the main organ of the immunity. In this ascidian, for the first time we show, by immunohistochemistry and in situ hybridization methods, that these two immune-related genes are expressed in the gastric epithelium of naïve ascidians, whereas the galectins appear to be only contained in the intestine columnar epithelium. In addition, according to previous results on the pharynx, the genes are also expressed and galectins produced by hemocytes scattered in the connective tissue surrounding the gut. The genes expression and galectin localization in several tissues, including the previous findings on the transcription upregulation, the constitutive expression of these genes by endostylar zones and by the gastric epithelium suggest a potential multifunctional role of these galectins. In this respect, it is of interest to define where the CiLgals are normally found as related to the tissue functions. Such an approach should be a starting point for further investigations. Copyright © 2017 Elsevier Ltd. All rights reserved.

O TOŻSAMOŚCI I POLITYCE

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Katarzyna Warmińska

2015-03-01

Full Text Available Ostatnie dekady przyniosły znaczące zmiany w sferze stosunków etnicznych w Polsce. Można było zaob- serwować wzrastającą aktywność społeczności mniejszościowych, które stają się w coraz większym stopniu aktywnymi, coraz lepiej zorganizowanymi aktorami na scenie publicznej. W bardziej otwarty sposób komunikują swoje potrzeby, cele i wizje świata. Chcąc uchwycić istotę tych przemian postanowiłam zaaplikować, do ich analizy, koncepcję polityki tożsamości. Moim celem jest ukazanie swoistej „logiki” działania politycznego grup tożsamościowych, ze szczególnym uwzględnieniem jego wymiaru etnicznego z jednoczesnym wskazaniem na pożytek z zastosowania tego pojęcia do analizy zjawisk etnicznych w Polsce. Jako empiryczną egzemplifikację potraktowałam społeczność kaszubską.

Dyskusja wokół celu sprawozdawczości finansowej opartej na MSSF

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Edyta Łazarowicz

2016-07-01

Full Text Available Celem artykułu jest analiza i ocena propozycji zmian odnośnie do celu sprawozdawczości finansowej opartej na Międzynarodowych Standardach Sprawozdawczości Finansowej (MSSF przedstawionych w komentarzach do projektu Założeń koncepcyjnych sprawozdawczości finansowej (2015. Większość respondentów uważa, że w celu sprawozdawczości finansowej należy zwiększyć znaczenie dostarczania informacji o wypełnieniu funkcji powierniczej przez kierownictwo (stewardship. Ponadto proponują oni przedstawienie definicji stewardship w Założeniach koncepcyjnych oraz wskazanie konsekwencji zmiany celu sprawozdawczości finansowej dla przyszłego tworzenia standardów i dla sporządzania sprawozdań finansowych. Z analizy komentarzy i przeglądu literatury wynika, że cel sprawozdawczości finansowej powinien być zmieniony. Sprawą dyskusyjną pozostaje jednak, czy stewardship powinien być odrębnym celem. Niestety, jest za mało badań dotyczących relacji pomiędzy stewardship i użytecznością decyzyjną. Ich wyniki mogłyby wskazać twórcom standardów rachunkowości potencjalne kompromisy i konflikty między nimi.

Regression Analysis to Identify Factors Associated with Household Salt Iodine Content at the Sub-National Level in Bangladesh, India, Ghana and Senegal

Directory of Open Access Journals (Sweden)

Jacky Knowles

2018-04-01

Full Text Available Regression analyses of data from stratified, cluster sample, household iodine surveys in Bangladesh, India, Ghana and Senegal were conducted to identify factors associated with household access to adequately iodised salt. For all countries, in single variable analyses, household salt iodine was significantly different (p < 0.05 between strata (geographic areas with representative data, defined by survey design, and significantly higher (p < 0.05 among households: with better living standard scores, where the respondent knew about iodised salt and/or looked for iodised salt at purchase, using salt bought in a sealed package, or using refined grain salt. Other country-level associations were also found. Multiple variable analyses showed a significant association between salt iodine and strata (p < 0.001 in India, Ghana and Senegal and that salt grain type was significantly associated with estimated iodine content in all countries (p < 0.001. Salt iodine relative to the reference (coarse salt ranged from 1.3 (95% CI 1.2, 1.5 times higher for fine salt in Senegal to 3.6 (95% CI 2.6, 4.9 times higher for washed and 6.5 (95% CI 4.9, 8.8 times higher for refined salt in India. Sub-national data are required to monitor equity of access to adequately iodised salt. Improving household access to refined iodised salt in sealed packaging, would improve iodine intake from household salt in all four countries in this analysis, particularly in areas where there is significant small-scale salt production.

Identyfikacja wielokryterialnego modelu istotności pompowni melioracyjnych na terenie Polski

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Wojciech Sałabun

2015-09-01

Full Text Available Niniejsza praca omawia istotny problem związany z klasyfikacją i właściwym zdefiniowaniem wielkości pompowni melioracyjnych. Podstawowa definicja wielkości jest bardzo szeroka, zatem ze względu na liczbę objaśniających ją parametrów wymaga precyzyjnego uściślenia. W dotychczasowych ocenach rozmiarów pompowni melioracyjnych posługiwano się na ogół wrażeniami osobistymi opartymi na subiektywnym odczuciu, które z kolei jest oparte na nieznanej liczbie parametrów. Pojawiające się przy tym trudności z określeniem przynależności obiektów do danej grupy wielkości wynikały głównie z luk informacyjnych dotyczących właściwej granicy podziału pomiędzy poszczególnymi grupami. W niniejszej pracy, do klasyfikacji i podziału pompowni według ich wielkości zastosowano takie ich parametry jak: moc nominalna pompowni P w kW, wydajność całkowita Q w m3 · s oraz zasięg oddziaływania pompowni Fp w ha, dla 270 losowo wybranych obiektów melioracyjnych w Polsce. Do rozwiązania problemu wykorzystano jedną z wielokryterialnych metod podejmowania decyzji (MCDM, opartą na mechanizmach logiki rozmytej, noszącą nazwę metody obiektów charakterystycznych (COMET.

Convergências entre a Ciência da Informação e as Ciências Cognitivas

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Aida Varela Varela

2016-06-01

Full Text Available Apresentam-se as convergências entre a Ciência da Informação e as Ciências Cognitivas, buscando argumentos, fundamentos para fomentar e produzir o saber e o fazer, potencializando estudos e aproximações. Para tal, reflete-se sobre conhecimentos e necessidades, os principais representantes das correntes cognitivas, como substrato aos processos de recuperação, compreensão, reflexão e criticidade essenciais à construção do conhecimento científico, com destaque para o domínio dos vários níveis de leitura para buscar e usar a informação. Utiliza-se como metodologia revisão bibliográfica, com estabelecimento de diálogos com autores clássicos e contemporâneos das áreas em questão. Conclui-se que é preciso se destacar o caráter paradigmático, bem como outras dimensões das construções conceituais e práticas das duas áreas em foco, principalmente os concentrar as pesquisas nos estudos cognitivos para subsidiar a busca da informação com autonomia e garantia de desenvolvimento pessoal, com maior contribuição num contexto de constantes mudanças.

Modeling Solute Thermokinetics in LiCI-KCI Molten Salt for Nuclear Waste Separation

Energy Technology Data Exchange (ETDEWEB)

Morgan, Dane; Eapen, Jacob

2013-10-01

Recovery of actinides is an integral part of a closed nuclear fuel cycle. Pyrometallurgical nuclear fuel recycling processes have been developed in the past for recovering actinides from spent metallic and nitride fuels. The process is essentially to dissolve the spent fuel in a molten salt and then extract just the actinides for reuse in a reactor. Extraction is typically done through electrorefining, which involves electrochemical reduction of the dissolved actinides and plating onto a cathode. Knowledge of a number of basic thermokinetic properties of salts and salt-fuel mixtures is necessary for optimizing present and developing new approaches for pyrometallurgical waste processing. The properties of salt-fuel mixtures are presently being studied, but there are so many solutes and varying concentrations that direct experimental investigation is prohibitively time consuming and expensive (particularly for radioactive elements like Pu). Therefore, there is a need to reduce the number of required experiments through modeling of salt and salt-fuel mixture properties. This project will develop first-principles-based molecular modeling and simulation approaches to predict fundamental thermokinetic properties of dissolved actinides and fission products in molten salts. The focus of the proposed work is on property changes with higher concentrations (up to 5 mol%) of dissolved fuel components, where there is still very limited experimental data. The properties predicted with the modeling will be density, which is used to assess the amount of dissolved material in the salt; diffusion coefficients, which can control rates of material transport during separation; and solute activity, which determines total solubility and reduction potentials used during electrorefining. The work will focus on La, Sr, and U, which are chosen to include the important distinct categories of lanthanides, alkali earths, and actinides, respectively. Studies will be performed using LiCl-KCl salt

Luz, arte, ciência... ação! Lights, art, science - action!

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Thelma Lopes

2005-01-01

Full Text Available O principal objetivo do presente artigo é refletir sobre as principais interações entre teatro, ciência e tecnologia, ao longo da história do teatro, e discutir, a partir de nossa experiência no Ciência em Cena, espaço integrante do Museu da Vida, de que modos essas interações podem estar presentes no cotidiano de um museu de ciências. A palavra 'ciência' deve ser compreendida aqui em sentido amplo, englobando não apenas as ciências naturais, mas também as ciências humanas, assim como a palavra 'tecnologia' deve ser associada à ciência aplicada. Arte e ciência serão entendidas como processos criativos, como formas de representação do mundo e expressão do conhecimento humano.The article offers some reflections on the main interactions between theater, science, and technology down through the history of theater. Based on our experience at "Science in the Spotlight", part of the Casa de Oswaldo Cruz's Museum of Life, we discuss how these interactions can be part of a science museum's daily activities. We use the word 'science' in its broad sense, encompassing not only the natural but human sciences as well; likewise, we use the word 'technology' as it relates to applied science. Art and science are understood here as creative processes, as ways of representing the world and expressing human knowledge.

Analiza wielkości i zmienności zużycia wody w kampusie Szkoły Głównej Gospodarstwa Wiejskiego w Warszawie

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Piotr Wichowski

2015-10-01

Full Text Available W artykule przedstawiono badania wielkości i zmienności zużycia wody w kampusie SGGW w roku akademickim 2012/13. Przeciętne jednostkowe zużycie wody w okresie, kiedy realizowane są zajęcia dydaktyczne, wyniosło 29,3 dm3·d–1 dla studenta studiów stacjonarnych i 23,2 dm3·d–1 dla studenta studiów niestacjonarnych. W okresie wakacyjnym wskaźniki te są niższe i wynoszą odpowiednio 15,2 oraz 11,4 dm3·d–1. Wskaźniki te wyznaczono bez uwzględnienia zużycia wody w akademikach. Współczynnik nierównomierności dobowej dla całego kampusu wyniósł 1,54 i był zbliżony do współczynnika nierównomierności godzinowej, wynoszącego 1,52. Najwyższe miesięczne zużycie wody wystąpiło w czerwcu i było o 85% większe od najniższego, które wystąpiło w sierpniu. W cyklu tygodniowym najwyższe zużycie wody obserwowano we wtorki, a najniższe w niedziele. Przeciętne rozbiory wtorkowe są wyższe od rozbiorów niedzielnych o 31,5%. Szczyty rozbiorów w ciągu doby przypadały w godzinach 10–15 oraz 23–01.

Gender-based differences on the association between salt-sensitive genes and obesity in Korean children aged between 8 and 9 years.

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Myoungsook Lee

Full Text Available High sodium intake is associated with the development of chronic diseases such as obesity. Although its role in obesity remains controversial, there may be a correlation between salt sensitivity and the early onset of chronic diseases in obese children.In all, 2,163 Korean children (1,106 boys and 1,057 girls aged 8-9 years were recruited from seven elementary schools in Seoul. To evaluate whether obesity risk was modulated by the salt sensitivity, 11 SNPs related to salt sensitive genes (SSG became the target of sodium intakes in obese children.BP, HOMA-IR, LDLc, TG, and the girls' sodium intake significantly increased, but HDLc significantly decreased with increase in BMI. Regardless of sex, the obesity risk was 5.27-fold (CI; 1.320-27.560 higher in the Q2 to Q5 of sodium intake adjusted by energy (4044.9-5058.9 mg/day than in the lowest Q1 level (2287.6 mg/day in obese children. BP was sensitively dependent on insulin resistance and lipid accumulation in all subjects; however, sodium intake may be an independent risk factor of obesity without increasing BP in girls. GRK4 A486V mutant homozygote was highly distributed in the obese group, but other SNPs had no impact. The obesity risk increased 7.06, 16.8, and 46.09-fold more in boys with GRK4 A486V, ACE, and SLC12A3 mutants as sodium intake increased. Among girls, the obesity risk increased in GRK4 A486V heterozygote and CYP11β-2 mutant homozygote although sodium intake was relatively lower, implying that ACE, SLC12A, CYP11β-2, and GRK4 A486V polymorphisms showed gender-based differences with regard to interaction between sodium intake and obesity.A high sodium intake markedly increased the obesity risk in variants of GRK4 A486V regardless of sex. The obesity risk increased with GRK4 A486V, ACE, and SLC12A3 variants in boys, whereas it increased with GRK4 A486V and CYP11B2 variants in girls as sodium intake increased. Obese children with the specific gene variants are recommended to reduce

Gender-based differences on the association between salt-sensitive genes and obesity in Korean children aged between 8 and 9 years.

Science.gov (United States)

Lee, Myoungsook; Kim, Mi Kyung; Kim, Seon-Mee; Park, Hyesoon; Park, Chang Gyu; Park, Hye Kyung

2015-01-01

High sodium intake is associated with the development of chronic diseases such as obesity. Although its role in obesity remains controversial, there may be a correlation between salt sensitivity and the early onset of chronic diseases in obese children. In all, 2,163 Korean children (1,106 boys and 1,057 girls) aged 8-9 years were recruited from seven elementary schools in Seoul. To evaluate whether obesity risk was modulated by the salt sensitivity, 11 SNPs related to salt sensitive genes (SSG) became the target of sodium intakes in obese children. BP, HOMA-IR, LDLc, TG, and the girls' sodium intake significantly increased, but HDLc significantly decreased with increase in BMI. Regardless of sex, the obesity risk was 5.27-fold (CI; 1.320-27.560) higher in the Q2 to Q5 of sodium intake adjusted by energy (4044.9-5058.9 mg/day) than in the lowest Q1 level (2287.6 mg/day) in obese children. BP was sensitively dependent on insulin resistance and lipid accumulation in all subjects; however, sodium intake may be an independent risk factor of obesity without increasing BP in girls. GRK4 A486V mutant homozygote was highly distributed in the obese group, but other SNPs had no impact. The obesity risk increased 7.06, 16.8, and 46.09-fold more in boys with GRK4 A486V, ACE, and SLC12A3 mutants as sodium intake increased. Among girls, the obesity risk increased in GRK4 A486V heterozygote and CYP11β-2 mutant homozygote although sodium intake was relatively lower, implying that ACE, SLC12A, CYP11β-2, and GRK4 A486V polymorphisms showed gender-based differences with regard to interaction between sodium intake and obesity. A high sodium intake markedly increased the obesity risk in variants of GRK4 A486V regardless of sex. The obesity risk increased with GRK4 A486V, ACE, and SLC12A3 variants in boys, whereas it increased with GRK4 A486V and CYP11B2 variants in girls as sodium intake increased. Obese children with the specific gene variants are recommended to reduce their sodium

Ciências Humanas e Sociais: ciências moles? A propósito do trabalho científico nesta contemporaneidade

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Maria Adélia Aparecida de Souza

2011-07-01

Full Text Available Este ensaio busca atender uma velha e interminável discussão sobre uma questão que longe de ser científica é, sobretudo, política, qual seja a classificação das ciências. A Geografia tem oscilado nessas classificações: ora é uma ciência humana, social, ora é uma ciência da natureza. Este estímulo é o motivo principal da realização deste ensaio que, inspirado em uma interessante reflexão de Abraham Moles, prêmio Nobel de Matemática, quando sugere que reflitamos com seriedade científica e acadêmica sobre esse debate. Esse autor propõe corajosamente que as ciências humanas sejam elas sim consideradas “ciências duras”. Aqui é defendida a tese de que, dadas as características e dinâmicas do mundo do presente, as classificações carecem de um processo de discussão condizente com a essência do mundo de hoje, que reverte por vezes o conhecimento pré-estabelecido. Sugere-se, por exemplo, nesta perspectiva, que o espaço geográfico, por ser uma instância social, tal como a economia, a política e a cultura, seja considerado uma categoria social de análise e não um palco de realização da vida, como tem sido considerado pela geografia descritiva, completamente ultrapassada pela velocidade do mundo e pelos sistemas técnicos disponíveis. Resumé SCIENCES HUMAINES ET SOCIALES: SCIENCES "MOLLES"? A PROPOS DU TRAVAIL SCIENTIFIQUE DANS LA CONTEMRAINETÉ Ce teste cherche à participer d´une interminable discussion sur question du classement des sciences. Catte discussion, loin d'être scientifique ou académique est uni discussion politique. Une source d'inspiration de cette reflexion a été I'oeuvre de Abraham Moles, Prix Nobel de Mathématique. Eant la Géographie une science que parfois est classée comme science de la nature, parfois comme science humaine et sociale. Catte discussion a inspirée aussi cet article. II attire I' ATTENTION SUR LA necessité, pour cette de prendre en consideration les

CI in the work place: does involving the HRM function make any difference?

DEFF Research Database (Denmark)

Hyland, Paul; Becker, Karen; Sload, Terry

2008-01-01

benefit the organisation's performance. The HRM function is often given the task of championing cultural change and managing aspects of training and learning, and it would appear that involvement of HRM professionals would enhance CI efforts and assist in the timely solution of issues within the CI......People are central to successful Continuous Improvement (CI), and in larger organisations a Human Resource Management (HRM) function is responsible for people related issues. Central to CI is learning and a culture that supports CI. Learning needs to be both individual and organisational, and must...

Nursing domain of CI governance: recommendations for health IT adoption and optimization.

Science.gov (United States)

Collins, Sarah A; Alexander, Dana; Moss, Jacqueline

2015-05-01

There is a lack of recommended models for clinical informatics (CI) governance that can facilitate successful health information technology implementation. To understand existing CI governance structures and provide a model with recommended roles, partnerships, and councils based on perspectives of nursing informatics leaders. We conducted a cross-sectional study through administering a survey via telephone to facilitate semistructured interviews from June 2012 through November 2012. We interviewed 12 nursing informatics leaders, across the United States, currently serving in executive- or director-level CI roles at integrated health care systems that have pioneered electronic health records implementation projects. We found the following 4 themes emerge: (1) Interprofessional partnerships are essential. (2) Critical role-based levels of practice and competencies need to be defined. (3) Integration into existing clinical infrastructure facilitates success. (4) CI governance is an evolving process. We described specific lessons learned and a model of CI governance with recommended roles, partnerships, and councils from the perspective of nursing informatics leaders. Applied CI work is highly interprofessional with patient safety implications that heighten the need for best practice models for governance structures, adequate resource allocation, and role-based competencies. Overall, there is a notable lack of a centralized CI group comprised of formally trained informaticians to provide expertise and promote adherence to informatics principles within EHR implementation governance structures. Our model of the nursing domain of CI governance with recommended roles, partnerships, and councils provides a starting point that should be further explored and validated. Not only can the model be used to understand, shape, and standardize roles, competencies, and structures within CI practice for nursing, it can be used within other clinical domains and by other informaticians

The Relation between Nonverbal IQ and Postoperative CI Outcomes in Cochlear Implant Users: Preliminary Result

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Mina Park

2015-01-01

Full Text Available Objectives. This study assessed the correlation between performance intelligence and the postoperative cochlear implant (CI outcome in Korean-speaking children. In addition, the relationship between the performance intelligence subscales and the post-CI speech outcome was evaluated. Materials and Methods. Thirteen pediatric CI users (five males, eight females; median age at implantation 6.2 (range 1.3–14.2 years; median age at intelligence test 9.3 (range 5–16 years who were tested using the Korean Educational Development Institute-Wechsler Intelligence Scale for children were studied. The correlations between the intelligence scores and 1-2 years postoperative Categories of Auditory Performance (CAP scores and between subscales of performance and 1-2 years postoperative CAP scores were analyzed. Results. There was no correlation between the categories of verbal intelligence quotient (IQ and performance IQ for “mentally retarded” and “average,” respectively (Spearman’s rho = 0.42, P=0.15. There was a strong correlation between performance IQ and the postoperative CAP scale (Spearman’s rho = 0.8977, P=0.0008. “Picture arrangement” and “picture completion,” reflecting social cognition, were strongly correlated with the postoperative CAP scales. Conclusion. Performance intelligence, especially social cognition, was strongly related to the postoperative CI outcome of cochlear implant users. Therefore, auditory rehabilitation, including social rehabilitation, should maximize the postoperative CI outcomes.

The configuration-driven table CI method and comparison with integral-driven CI procedures

International Nuclear Information System (INIS)

Buenker, R.J.

1980-01-01

A new configuration-driven CI algorithm is outlined which eliminates the need for explicit comparison of pairs of Slater determinants through the use of a series of compact tables. In this scheme each pair of configurations is either shown to be non-interacting or to fall into one of nine cases, each of which is characterized fully once certain orbital permutations are determined. The program is divided into three parts: a case structure analysis step including integral label generation, a sort of the required electron repulsion integrals, and finally a procedure in which the foregoing information is combined with tabulated directions for the evaluation of the necessary Hamiltonian matrix elements over spin-adapted functions. Timing improvements of up to more than a factor of four have been achieved with the new algorithm

Concepções de ciência presentes na divulgação e prática de instituições não formais de ensino de ciências

OpenAIRE

Thayse Zambon Barbosa Aragão

2013-01-01

Esse trabalho tem como objetivo apresentar quais concepções de ciência estão presentes no discurso e prática de instituições de educação não formal. Para tanto investigaram-se quatro importantes instituições brasileiras integrantes deste universo, escolhidas a partir de indicações de seus pares: Museu da Vida (RJ), Espaço Ciência (PE), Museu de Ciência e Tecnologia da PUCRS (RS) e Estação Ciência (SP). Foram analisados os sites dessas instituições, utilizando-se como metodologia a análise ...

Ciência e Direitos Humanos: direitos culturais e maternidade

OpenAIRE

Lopes, Allice Ferreira; Gomes, Ana Lucia de Abreu

2018-01-01

O objetivo desse artigo é analisar a ligação entre ciência e cultura bem como seu impacto entre as mulheres, especialmente durante a maternidade, destacando a recente conquista dos espaços públicos. Foi realizado levantamento bibliográfico sobre o tema dos Direitos Humanos das Mulheres e a visão sobre as mulheres na Ciência. Posteriormente é apresentada pesquisa sobre legislações e normativas disponíveis nos portais virtuais do Instituto do Patrimônio Histórico e Artístico Nacional, com desta...

Sprawozdawczość zintegrowana jako nowy obszar badań naukowych w rachunkowości

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Joanna Krasodomska

2015-06-01

Full Text Available Celem artykułu jest przedstawienie sprawozdawczości zintegrowanej jako interesującego, nowego obszaru badań naukowych w rachunkowości. Zakłada ona publikację raportu prezentującego, jak przyjęte przez przedsiębiorstwo strategia, zasady zarządzania, wyniki działalności i perspektywy rozwoju prowadzą do tworzenia wartości. W artykule omówiono stanowiące podstawę sprawozdawczości zintegrowanej koncepcje modelu biznesu oraz sześciu kapitałów. Na podstawie dokonanego przeglądu literatury przedstawiono kierunki badań z zakresu sprawozdawczości zintegrowanej, prezentowane w artykułach naukowych indeksowanych w bazach EBSCO i Emerald oraz postulowane przez Międzynarodową Radę ds. Zintegrowanej Sprawozdawczości (International Integrated Reporting Council – IIRC we współpracy ze Stowarzyszeniem Dyplomowanych Biegłych Księgowych (Association of Chartered Certified Accountants – ACCA i Międzynarodowym Stowarzyszeniem Edukacji Rachunkowości i Badań (International Association for Accounting Education & Research – IAAER. Wskazano też tematy opracowań podejmujących ten problem, przyjętych do prezentacji na Kongresie Europejskiego Stowarzyszenia Rachunkowości (European Accounting Association – EAA w Glasgow w kwietniu 2015 r. Analizą objęto również dorobek polskich autorów podejmujących w swoich badaniach problematykę sprawozdawczości zintegrowanej. Przegląd literatury dotyczącej sprawozdawczości zintegrowanej oraz obecnie prowadzonych badań pozwolił na zidentyfikowanie luk badawczych i wskazanie problemów wartych naukowych dociekań. Zaliczono do nich m.in. zagadnienia związane z modelem biznesu, koncepcją wartości, sześcioma kapitałami, jakością i istotnością raportów zintegrowanych, zaspokajaniem przez raporty zintegrowane potrzeb informacyjnych użytkowników oraz rolą księgowych i biegłych rewidentów w opracowywaniu i weryfikacji sprawozdawczości zintegrowanej. 

 Motywy wyboru wartości godziwej do wyceny środków trwałych w świetle pozytywnej teorii rachunkowości

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Katarzyna Bareja

2016-07-01

Full Text Available Celem artykułu jest zidentyfikowanie przyczyn wyboru wartości godziwej do wyceny środków trwałych w świetle trzech podstawowych hipotez pozytywnej teorii rachunkowości, sformułowanych przez Wattsa i Zimmermana. Stwierdzono, że podstawowym motywem jest dążenie do poprawy wskaźnika długu do kapitału własnego. W artykule wykorzystano metodę wnioskowania indukcyjnego.

Salt intake, obesity, and pre-hypertension among Iranian adults: a cross-sectional study

International Nuclear Information System (INIS)

Khosravi, A.; Toghianifar, N.; Sarrafzodegan, N

2012-01-01

Objective: Overweight and obese subjects are prone to have a high salt intake. This study was aimed to investigate the relationship between salt intake and pre hypertension among overweight and obese subjects. Methodology: This was across-sectional study performed in the setting of a community-based intervention: the Isfahan Healthy Heart Program (IHHP). In total, 806 subjects with normal blood pressure or pre hypertension entered the study. Salt intake, BMI, and blood pressure were measured using standard methods. Results: The salt intake was 9.19 +- 5.34, 11.6 6.87, and 11.64 +- 6.68 gm/d in normal-weight, overweight and obese subjects with normal blood pressure, respectively (p=0.0001). The values for normal-weight, overweight and obese pre hypertensive subjects were 12.04 +- 8.03, 12.41 +- 6.45, and 12.52+- 7.63 gm/d, respectively (p=0.236). The unadjusted odds ratio for pre hypertension among obese subjects was 4.78 (95% Cl: 2.38 - 9.60). The odds ratio was 4.73 (95% CI 2.19-10.19), 4.65 (95%CI 2.15-10.05), and 3.37 (95%CI 1.45-7.85) after adjustment for socio demographic characteristics, lifestyle factors, and salt intake, respectively. An increase of one gram per day in the daily salt intake increased the probability of having pre hypertension by 5% after adjusting for age, education, BMI, and lifestyle factors. Conclusion: The findings of this study support a role for high salt intake in the high blood pressure of overweight and obese subjects. (author)

Rak piersi w ciąży - odmienności procesu diagnostyki i leczenia = Breast cancer during pregnancy - differences in diagnostic and treatment procedures

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Magdalena Sowa

2016-09-01

85 -801 Bydgoszcz e – mail: magdalena.sowa@cm.umk.pl         Streszczenie Wprowadzenie: Rak piersi w ciąży jest rozpoznawany stosunkowo rzadko. W ostatnich dziesięciu latach w Europie można zauważyć wyraźną tendencję do odraczania macierzyństwa wśród młodych kobiet. Obecnie średnia wieku kobiet rodzących pierwsze dziecko wynosi 30 lat. Jednym z czynników ryzyka zachorowania na raka piersi jest wiek. Z uwagi na fakt, iż kobiety coraz później decydują się na macierzyństwo, a średnia wieku występowania raka piersi się obniża,  z tą szczególną sytuacją kliniczną lekarzom jak i kobietom przyjdzie się zmagać coraz częściej.  Cel pracy:Celem pracy była próba przybliżenia odmienności procesu diagnostyki i leczenia raka gruczołu piersiowego rozpoznanego w ciąży. Rozwinięcie:Z danych epidemiologicznych wynika, iż rak piersi jest najczęściej występującym nowotworem u kobiet ciężarnych.Szczególnie niebezpiecznym jest fakt, iż zmiany fizjologicznie zachodzące w organizmie kobiety już od pierwszych tygodni ciąży, mogą maskować pojawienie się guza i znacznie opóźniać wdrożenie procesu diagnostyki.  Choroba nowotworowa rozpoznana w czasie trwania ciąży jest zawsze dramatyczną i ogromnie stresującą sytuacją dla kobiety i jej najbliższych, dlatego proces diagnostyki i leczenia jest silnie zindywidualizowany, zaś maksymalny efekt terapeutyczny z jednoczesną ochroną nienarodzonego dziecka stanowi priorytet działań. Podsumowanie:Decyzje terapeutyczne podejmowane są po uwzględnieniu ogólnego stanu zdrowia pacjentki, stopnia zaawansowania klinicznego nowotworu, wieku ciążowego oraz postulatów samej pacjentki i jej najbliższych.W niniejszej pracy, posługując się metodą analizy piśmiennictwa szczegółowo omówiono odmienności w procesie diagnostyki i leczenia raka piersi u kobiet ciężarnych.   Słowa kluczowe: rak piersi, ciąża, diagnostyka, leczenie   Breast cancer during pregnancy

ANALIZA MOŻLIWOŚCI ZASTOSOWANIA ODPADOWEGO PYŁU BAZALTOWEGO W ZAPRAWIE CEMENTOWEJ

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Magdalena DOBISZEWSKA

2016-07-01

Full Text Available Rosnące zapotrzebowanie na surowce naturalne do produkcji materiałów budowlanych, spowodowało intensyfikację badań dotyczących możliwości wykorzystania w produkcji budowlanej materiałów odpadowych. Powszechnie, jako dodatek mineralny do cementu stosowany jest granulowany żużel wielkopiecowy, popiół lotny, czy też pył krzemionkowy. Podczas obróbki kruszywa stosowanego do produkcji mas mineralno-asfaltowych (MMA powstają duże ilości odpadów pylastych. Utylizacja tych odpadów stanowi obecnie duży problem w wielu wytwórniach MMA. W pracy dokonano analizy możliwości zastosowania odpadowego pyłu bazaltowego do produkcji zaprawy cementowej. Najpierw zbadano właściwości fizyczne i chemiczne zastosowanego pyłu bazaltowego. Celem określenia wpływu dodatku pyłu bazaltowego na niektóre właściwości zapraw przygotowano cztery mieszanki, w których pył bazaltowy stanowił częściowy zamiennik piasku w ilości 0-30% masy piasku. Badania doświadczalne dotyczyły analizy wpływu pyłu na wytrzymałość zapraw na ściskanie i zginanie po 2, 28 i 56 dniach dojrzewania próbek, mrozoodporności, nasiąkliwość oraz zdolności do kapilarnego podciągania wody. Następnie przeprowadzono badania dotyczące wpływu dodatku pyłu bazaltowego na mikrostrukturę oraz porowatość zaprawy. Wyniki przeprowadzonych badań wskazują na to, że pył bazaltowy może być stosowany do produkcji zapraw cementowych, jako substytut piasku naturalnego. Zastąpienie części piasku w zaprawie cementowej przez pył bazaltowy pozwoli na zagospodarowanie odpadu przemysłowego oraz wpłynie na poprawę niektórych cech zaprawy cementowej.

Selective labelling of apolipoproteins A-I and C-I at methionine residues by (TH) methyl exchange

Energy Technology Data Exchange (ETDEWEB)

Hancock, W.S.; Harding, D.R.K.; Barling, P.M.; Sparrow, J.T.

1985-01-01

Apolipoproteins C-I and A-I were radioactively labelled with tritium by (TH)-methyl exchange. The methionine residues were first methylated with (TH)-methyl iodide at pH4 and the reaction products were purified by gel filtration and cation exchange chromatography. The products were then demethylated with 2-mercaptoethanol (6 M) at pH 8.6 to regenerate the apolipoproteins in an unmodified but tritiated form. The specific radioactivity for apolipoprotein C-I and A-I was 3.5 x 10W and 1.5 x 10X dpm/pmol respectively. The properties of (TH)-apolipoprotein C-I were examined by reversed phase HPLC and by incorporation into very low density lipoproteins (VLDL).

Identyfikacja wielokryterialnego modelu istotności pompowni melioracyjnych na terenie Polski

OpenAIRE

Wojciech Sałabun; Michał Napierała; Jerzy Bykowski

2015-01-01

Niniejsza praca omawia istotny problem związany z klasyfikacją i właściwym zdefiniowaniem wielkości pompowni melioracyjnych. Podstawowa definicja wielkości jest bardzo szeroka, zatem ze względu na liczbę objaśniających ją parametrów wymaga precyzyjnego uściślenia. W dotychczasowych ocenach rozmiarów pompowni melioracyjnych posługiwano się na ogół wrażeniami osobistymi opartymi na subiektywnym odczuciu, które z kolei jest oparte na nieznanej liczbie parametrów. Pojawiające się przy...

CiF-CK: An Architecture for Social NPCs in Commercial Games

NARCIS (Netherlands)

Guimaraes, Manuel; Santos, Pedro A.; Jhala, Arnav

2018-01-01

We present and describe CiF-CK — a social agent architecture that models reasoning about persistent social interactions to improve narrative engagement and play experience for human interactors. The architecture is inspired by McCoy et al’s Comme il-Faut (CiF) architecture that represented

Reported high salt intake is associated with increased prevalence of abdominal aortic aneurysm and larger aortic diameter in older men.

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Jonathan Golledge

Full Text Available Salt intake has been implicated in the pathogenesis of abdominal aortic aneurysm (AAA through studies in rodent models but not previously studied in humans. The aim of this study was to examine the association between reported addition of salt to food and the prevalence of AAA.A risk factor questionnaire which contained a question about salt intake was included as part of a population screening study for AAA in 11742 older men. AAA presence was assessed by abdominal ultrasound imaging using a reproducible protocol.The prevalence of AAA was 6.9, 8.5 and 8.6% in men who reported adding salt to food never, sometimes and always, respectively, p = 0.005. Addition of salt to food sometimes (odds ratio [OR]: 1.22, 95% confidence interval [CI]: 1.03-1.44 or always (OR: 1.23, 95% CI 1.04-1.47 was independently associated with AAA after adjustment for other risk factors including age, waist-hip ratio, blood pressure, history of hypertension, high cholesterol, angina, diabetes, myocardial infarction and stroke. Salt intake was also independently associated with aortic diameter (beta 0.023, p = 0.012. In men with no prior history of hypertension, high cholesterol, angina, myocardial infarction or stroke (n = 4185, the association between addition of salt to food sometimes (OR: 1.41, 95% CI 0.96-2.08 or always (OR: 1.52, 95% CI 1.04-2.22 and AAA remained evident.Reported salt intake is associated with AAA in older men. Additional studies are needed to determine whether reducing salt intake would protect against AAA.

Wpływ wykształcenia oraz aktywności fizycznej rodziców na poziom rozwoju zdolności szybkościowych dziewcząt wiejskich w młodszym wieku szkolnym

Directory of Open Access Journals (Sweden)

Jarosław Fugiel

2009-06-01

Full Text Available Wstęp: Proces rozwoju motorycznego kształtowany jest przez czynniki biogeograficzne, społeczno-ekonomiczne oraz tryb życia, wynika również ze stanu zaawansowania rozwoju somatycznego. Znaczącą rolę przypisuje się zwłaszcza aktywności fizycznej, której poziom różnicowany jest głównie przez takie czynniki jak płeć, wiek,miejsce zamieszkania czy wykształcenie. Poziom aktywności fizycznej znacznie różni się w środowisku miejskim i wiejskim. Sytuacja ta w dużym stopniu wynika z odmiennych warunków socjalno-bytowych, różnic w ilości i dostępności do bazy sportowej oraz niższej świadomości dotyczącej promocji zdrowia. Również wykształcenie rodziców, które wpływa na poziom świadomości dotyczącej kształtowania rozwoju fizycznego potomstwa, jest niższe na wsi w porównaniu do populacji miejskiej. Czynniki te mogą decydować o poziomie i charakterze aktywności fizycznej oraz mogą wpływać na sprawność motoryczną dzieci i młodzieży wiejskiej. Celem pracy była ocena wpływu wykształcenia oraz aktywności fizycznej rodziców na poziom sprawności motorycznej dziewcząt wiejskich z Legnicko-Głogowskiego Zagłębia Miedziowego. Materiał i metody: Materiał do pracy zgromadzono w 1998 r. na terenie Zagłębia Miedziowego. Zbadano 69 dziewcząt w wieku 9 lat z wiejskich szkół okolic Legnicy i Głogowa. Zmierzono wysokość i masę ciała oraz przeprowadzono testy sprawności fizycznej: skok w dal z miejsca, rzut 1 kg piłką lekarską, bieg wahadłowy 10x5m i stukanie w krążki. Informacje na temat wykształcenia rodziców oraz ich aktywności fizycznej w zakresie uprawiania sportu uzyskano za pomocą ankiety. W analizie wykorzystano podstawowe obliczenia statystyczne oraz obliczono test t-Studenta dla grup niezależnych. Wyniki i wnioski: 1. Wykształcenie średnie lub wyższe ojca i matki wpływa na uzyskanie wyższego poziomu rozwoju somatycznego córek. Dziewczęta z tych grup uzyskują r

Detection of CI line emission towards the oxygen-rich AGB star omi Ceti

Science.gov (United States)

Saberi, M.; Vlemmings, W. H. T.; De Beck, E.; Montez, R.; Ramstedt, S.

2018-05-01

We present the detection of neutral atomic carbon CI(3P1-3P0) line emission towards omi Cet. This is the first time that CI is detected in the envelope around an oxygen-rich M-type asymptotic giant branch (AGB) star. We also confirm the previously tentative CI detection around V Hya, a carbon-rich AGB star. As one of the main photodissociation products of parent species in the circumstellar envelope (CSE) around evolved stars, CI can be used to trace sources of ultraviolet (UV) radiation in CSEs. The observed flux density towards omi Cet can be reproduced by a shell with a peak atomic fractional abundance of 2.4 × 10-5 predicted based on a simple chemical model where CO is dissociated by the interstellar radiation field. However, the CI emission is shifted by 4 km s-1 from the stellar velocity. Based on this velocity shift, we suggest that the detected CI emission towards omi Cet potentially arises from a compact region near its hot binary companion. The velocity shift could, therefore, be the result of the orbital velocity of the binary companion around omi Cet. In this case, the CI column density is estimated to be 1.1 × 1019 cm-2. This would imply that strong UV radiation from the companion and/or accretion of matter between two stars is most likely the origin of the CI enhancement. However, this hypothesis can be confirmed by high-angular resolution observations.

Isenção da ciência, neutralidade da análise

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Daniel Menezes Coelho

2012-01-01

Full Text Available O artigo discute as relações entre a psicanálise e a ciência, especialmente no que tange aos seus métodos de investigação e trabalho. Para isso, tomamos como objeto a noção de neutralidade, tal como podemos apreendê-la na clínica da psicanálise, para confrontá-la com o que chamamos de isenção no campo da ciência, que não quer dizer outra coisa que a neutralidade proposta lá. Veremos que, apesar da clara filiação da noção psicanalítica para com a noção vinda da ciência, a neutralidade clínica da psicanálise toma outro rumo, que se pode mesmo opor ao sentido do termo na ciência. Enquanto em ciência o termo quer significar um processo de purificação e de seleção, em psicanálise ele surge como a exigência de nada selecionar.

Ciąża i poród u chorych na stwardnienie rozsiane

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Małgorzata Czernichowska-Kotiuszko

2014-04-01

Full Text Available Stwardnienie rozsiane (łac. sclerosis multiplex, SM jest główną przyczyną niepełnosprawności u młodych dorosłych i jak większość chorób autoimmunologicznych częściej dotyczy kobiet. Wpływ ciąży na przebieg SM wzbudza zainteresowanie od wielu lat, a w ostatnim okresie stanowi temat badań wieloośrodkowych. Ciąża to zwykle okres bardzo dobrego samopoczucia chorych, najczęściej bez rzutów. Wynika to ze zmiany reaktywności immunologicznej na korzyść reakcji przeciwzapalnych związanych z limfocytami Th2 i cytokinami antyzapalnymi (interleukina 4, 5, 6, 10, TGF-β. Po porodzie zmienia się reaktywność immunologiczna i aktywność choroby wzrasta. Większość badań nie wykazała ogólnego negatywnego wpływu ciąży na niesprawność długoterminową związaną z SM; stwardnienie rozsiane nie ma negatywnego wpływu na przebieg ciąży, porodu i stan dziecka, dlatego chore kobiety mogą planować potomstwo. Choroba nie zwiększa ryzyka powikłań w ciąży i podczas porodu ani wad wrodzonych u dziecka w porównaniu z populacją ogólną. Jednakże każda terapia immunomodulująca jest przeciwwskazana w ciąży. Jeśli pacjentka decyduje się na dziecko, powinna przerwać leczenie; zaleca się również przerwę od leków przed zajściem w ciążę. W pracy podsumowano dostępne informacje na temat klinicznych problemów dotyczących ciąży i porodu u chorych na SM oraz oceniono zagrożenia dla dziecka związane z podawaniem leków.

Random comparison study of the clinical response to 153Sm-EDTMP 1.0 mCi/kg and 1.5 mCi/kg

International Nuclear Information System (INIS)

Pan, Z.; Zhu, S.

2001-01-01

Sixty-seven patient with painful bone metastases were randomized to two groups. Group 1 (n=34) received 1.0 mCi/kg of 153 Sm-EDTMP and group II (n=33) received 1.5 mCi/kg. All of them met inclusion criteria and there was no significantly difference between the basic conditions of two groups. After receiving 153 Sm-EDTMP intravenously, all patients were kept in close follow-up weekly with blood counting, physician visiting and collecting patient's self-filling-in diary including pain score, Karnofsky performance scale and analgesic consumption. The follow-up duration was six weeks. The final overall condition assessed by physician were graded into no change (including worse), slight relief, significant relief and complete relief. Only significant relief and complete relief were considered as effectiveness for pain relief. Haematological toxicity grade was evaluated based on the nadir of WBC ad PLT counts. The results indicated that the higher dosage group had a higher effectiveness rate (75.76%) compared to the lower dosage group (67.65%), but without statistic significance (x 2 =0.5365, 0.25 153 Sm-EDTMP could be used for those patients with better haematological function and 1.0 mCi/kg used for those patients with poorer haematological function. (author)

PENGUASAAN KERAJAAN TARUMANEGARA TERHADAP KAWASAN HULU CI SADANE THE CONTROL OF TARUMANEGARA KINGDOM TO THE CI SADANE UPSTREAM AREA

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Endang Widyastuti

2016-06-01

Full Text Available ABSTRACT As we know that the oldest kingdom in West Java is the Kingdom Tarumanegara. Authentic evidence of the existence of such is the kingdom of seven inscriptions, of which five were found in the upstream region is now administratively Cisadane including Bogor regency. Three of the five inscriptions indicate the possession of territory by Tarumanegara kingdom. This indicates that the upstream region Cisadane is an area that is quite important and has the potential to be controlled by Tarumanegara.   Key words:upstream of Ci Sadane, Tarumanegara kingdom, control area   ABSTRAK Sebagaimana diketahui bahwa kerajaan tertua di Jawa Barat adalah Kerajaan Tarumanegara. Bukti otentik mengenai keberadaan kerajaan tersebut adalah adanya tujuh prasasti, yang lima diantaranya ditemukan di kawasan Hulu Cisadane yang sekarang secara administratif termasuk wilayah Kabupaten Bogor. Tiga diantara kelima prasasti tersebut menunjukkan penguasaan wilayah tersebut oleh Kerajaan Tarumanegara. Hal ini mengindikasikan bahwa kawasan hulu cisadane merupakan kawasan yang cukup penting dan mempunyai potensi yang harus dikuasai oleh Tarumanegara.   Kata Kunci:hulu Ci Sadane, Kerajaan Tarumanegara, penguasaan wilayah.

Ceux-ci ne sont pas : [luuletused] / Kalju Kruusa

Index Scriptorium Estoniae

Kruusa, Kalju, pseud., 1973-

2003-01-01

Sisu: Ceux-ci ne sont pas ; Köögivahet ; "Taara..." ; "Pakane pistab pisikesi ..." ; "Meri on kaet mattklaasiga ; Pydemise päivil ; "Toas muusika mängib ..." ; "Jäin juustu imetlema ; "Mu elu on mustikas ..." ; Hingepidetus ; ŁNo me gusta la cocina

Healthcare Costs Associated with an Adequate Intake of Sugars, Salt and Saturated Fat in Germany: A Health Econometrical Analysis.

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Toni Meier

Full Text Available Non-communicable diseases (NCDs represent not only the major driver for quality-restricted and lost life years; NCDs and their related medical treatment costs also pose a substantial economic burden on healthcare and intra-generational tax distribution systems. The main objective of this study was therefore to quantify the economic burden of unbalanced nutrition in Germany--in particular the effects of an excessive consumption of fat, salt and sugar--and to examine different reduction scenarios on this basis. In this study, the avoidable direct cost savings in the German healthcare system attributable to an adequate intake of saturated fatty acids (SFA, salt and sugar (mono- & disaccharides, MDS were calculated. To this end, disease-specific healthcare cost data from the official Federal Health Monitoring for the years 2002-2008 and disease-related risk factors, obtained by thoroughly searching the literature, were used. A total of 22 clinical endpoints with 48 risk-outcome pairs were considered. Direct healthcare costs attributable to an unbalanced intake of fat, salt and sugar are calculated to be 16.8 billion EUR (CI95%: 6.3-24.1 billion EUR in the year 2008, which represents 7% (CI95% 2%-10% of the total treatment costs in Germany (254 billion EUR. This is equal to 205 EUR per person annually. The excessive consumption of sugar poses the highest burden, at 8.6 billion EUR (CI95%: 3.0-12.1; salt ranks 2nd at 5.3 billion EUR (CI95%: 3.2-7.3 and saturated fat ranks 3rd at 2.9 billion EUR (CI95%: 32 million-4.7 billion. Predicted direct healthcare cost savings by means of a balanced intake of sugars, salt and saturated fat are substantial. However, as this study solely considered direct medical treatment costs regarding an adequate consumption of fat, salt and sugars, the actual societal and economic gains, resulting both from direct and indirect cost savings, may easily exceed 16.8 billion EUR.

Healthcare Costs Associated with an Adequate Intake of Sugars, Salt and Saturated Fat in Germany: A Health Econometrical Analysis.

Science.gov (United States)

Meier, Toni; Senftleben, Karolin; Deumelandt, Peter; Christen, Olaf; Riedel, Katja; Langer, Martin

2015-01-01

Non-communicable diseases (NCDs) represent not only the major driver for quality-restricted and lost life years; NCDs and their related medical treatment costs also pose a substantial economic burden on healthcare and intra-generational tax distribution systems. The main objective of this study was therefore to quantify the economic burden of unbalanced nutrition in Germany--in particular the effects of an excessive consumption of fat, salt and sugar--and to examine different reduction scenarios on this basis. In this study, the avoidable direct cost savings in the German healthcare system attributable to an adequate intake of saturated fatty acids (SFA), salt and sugar (mono- & disaccharides, MDS) were calculated. To this end, disease-specific healthcare cost data from the official Federal Health Monitoring for the years 2002-2008 and disease-related risk factors, obtained by thoroughly searching the literature, were used. A total of 22 clinical endpoints with 48 risk-outcome pairs were considered. Direct healthcare costs attributable to an unbalanced intake of fat, salt and sugar are calculated to be 16.8 billion EUR (CI95%: 6.3-24.1 billion EUR) in the year 2008, which represents 7% (CI95% 2%-10%) of the total treatment costs in Germany (254 billion EUR). This is equal to 205 EUR per person annually. The excessive consumption of sugar poses the highest burden, at 8.6 billion EUR (CI95%: 3.0-12.1); salt ranks 2nd at 5.3 billion EUR (CI95%: 3.2-7.3) and saturated fat ranks 3rd at 2.9 billion EUR (CI95%: 32 million-4.7 billion). Predicted direct healthcare cost savings by means of a balanced intake of sugars, salt and saturated fat are substantial. However, as this study solely considered direct medical treatment costs regarding an adequate consumption of fat, salt and sugars, the actual societal and economic gains, resulting both from direct and indirect cost savings, may easily exceed 16.8 billion EUR.

Gender-Based Differences on the Association between Salt-Sensitive Genes and Obesity in Korean Children Aged between 8 and 9 Years

Science.gov (United States)

Kim, Seon-Mee; Park, Hyesoon; Park, Chang gyu; Park, Hye Kyung

2015-01-01

Background High sodium intake is associated with the development of chronic diseases such as obesity. Although its role in obesity remains controversial, there may be a correlation between salt sensitivity and the early onset of chronic diseases in obese children. Methods In all, 2,163 Korean children (1,106 boys and 1,057 girls) aged 8–9 years were recruited from seven elementary schools in Seoul. To evaluate whether obesity risk was modulated by the salt sensitivity, 11 SNPs related to salt sensitive genes (SSG) became the target of sodium intakes in obese children. Results BP, HOMA-IR, LDLc, TG, and the girls’ sodium intake significantly increased, but HDLc significantly decreased with increase in BMI. Regardless of sex, the obesity risk was 5.27-fold (CI; 1.320–27.560) higher in the Q2 to Q5 of sodium intake adjusted by energy (4044.9–5058.9 mg/day) than in the lowest Q1 level (2287.6 mg/day) in obese children. BP was sensitively dependent on insulin resistance and lipid accumulation in all subjects; however, sodium intake may be an independent risk factor of obesity without increasing BP in girls. GRK4 A486V mutant homozygote was highly distributed in the obese group, but other SNPs had no impact. The obesity risk increased 7.06, 16.8, and 46.09-fold more in boys with GRK4 A486V, ACE, and SLC12A3 mutants as sodium intake increased. Among girls, the obesity risk increased in GRK4 A486V heterozygote and CYP11β-2 mutant homozygote although sodium intake was relatively lower, implying that ACE, SLC12A, CYP11β-2, and GRK4 A486V polymorphisms showed gender-based differences with regard to interaction between sodium intake and obesity. Conclusion A high sodium intake markedly increased the obesity risk in variants of GRK4 A486V regardless of sex. The obesity risk increased with GRK4 A486V, ACE, and SLC12A3 variants in boys, whereas it increased with GRK4 A486V and CYP11B2 variants in girls as sodium intake increased. Obese children with the specific gene

A modified CAS-CI approach for an efficient calculation of magnetic exchange coupling constants

Science.gov (United States)

Fink, Karin; Staemmler, Volker

2013-09-01

A modification of the conventional wavefunction-based CAS-CI method for the calculation of magnetic exchange coupling constants J in small molecules and transition metal complexes is presented. In general, CAS-CI approaches yield much too small values for J since the energies of the important charge transfer configurations are calculated with the ground state orbitals and are therefore much too high. In the present approach we improve these energies by accounting for the relaxation of the orbitals in the charge transfer configurations. The necessary relaxation energies R can be obtained in separate calculations using mononuclear or binuclear model systems. The method is applied to a few examples, small molecules, binuclear transition metal complexes, and bulk NiO. It allows to obtaining fairly reliable estimates for J at costs that are not higher than those of conventional CAS-CI calculations. Therefore, extended and very time-consuming perturbation theory (PT2), configuration interaction (CI), or coupled cluster (CC) schemes on top of the CAS-CI calculation can be avoided and the modified CAS-CI (MCAS-CI) approach can be applied to rather large systems.

Somatyczna determinacja płciowa w nadwadze i otyłości

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Michał Zych

2015-12-01

Full Text Available Wstęp: Somatyczne wielkości, takie jak masa (Mc i wysokość ciała (Wc, są używane do wyliczania wskaźników wagowo--wzrostowych i stanowią pomoc w diagnozowaniu nadwagi i otyłości. Cel pracy: Celem pracy jest ocena nadwagi i otyłości kobiet i mężczyzn w świetle prostych wskaźników somatycznych. Materiał i metody: W prezentowanej pracy porównano wskaźniki somatyczne 179 kobiet i 181 mężczyzn z nadwagą i otyłością. Do oceny somatycznej badanych użyto: Mc, Wc oraz wskaźników wagowo-wzrostowych: Queteleta, BMI, Rohrera i smukłości. Wyniki: W badanych grupach kobiety i mężczyźni byli w zbliżonym wieku, grupy te różniły się istotnie omawianymi wskaźnikami somatycznymi. Porównania podgrup kobiet i mężczyzn o podobnej wielkości BMI wykazały, że są oni w podobnym wieku i różnią się w zakresie Mc, Wc oraz wskaźników: Queteleta, Rohrera i smukłości. Natomiast między podgrupami kobiet, jak i między podgrupami mężczyzn, występowały istotne różnice wiekowe, Mc oraz wskaźników: BMI, Queteleta, Rohrera i smukłości. Wnioski: Powyższe dane wskazują, że pomimo braku różnic wieku między badanymi kobietami i mężczyznami z podobnym lub różnym BMI istnieje wyraźna somatyczna determinacja płciowa, natomiast w obrębie tej samej płci, różniącej się wskaźnikiem BMI, wiek badanych jest czynnikiem determinacji somatycznej. Wykazano też, że badane wskaźniki somatyczne mają różną moc predykcyjną w zakresie oceny nadwagi i stopnia otyłości badanych kobiet i mężczyzn.

Możliwości leczenia kamicy moczowodowej u dzieci

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Ewa Straż-Żebrowska

2010-09-01

Full Text Available Kamicą układu moczowego nazywamy schorzenie, w którym wytwarzane są złogi w obrębie nerek lub dróg moczowych. Obecnie obserwuje się wzrost częstości występowania kamicy. Szacuje się, iż częstość występowania kamicy układu moczowego wynosi 0,5-5% w grupie dorosłych i 0,1-5% u dzieci. Istotnym problemem jest wykrywanie złogów u małych dzieci, również u niemowląt. Biorąc pod uwagę coraz częstsze wykrywanie kamicy układu moczowego, jej nawrotowość i powikłania, ważne jest wypracowanie schematów leczniczych skutecznych i jednocześnie bezpiecznych, nawet przy konieczności ich kilkukrotnego powtarzania. Postępowanie zachowawcze jest skuteczne w 80%, w przypadkach złogów o wielkości do 4 mm. Powszechnie stosowane do lat 80. XX wieku leczenie operacyjne związane z nacięciem miąższu nerki obecnie w większości przypadków zastępowane jest metodami mniej inwazyjnymi, takimi jak ESWL, PCNL, URSL, a wskazania do leczenia chirurgicznego kamicy zostały znacznie ograniczone. W niniejszej pracy przedstawiono przypadek pacjentki z kamicą układu moczowego leczonej kilkakrotnie metodą ESWL bez efektu, a następnie z uwagi na obecność złogów w moczowodzie za pomocą URSL. Jednym z powikłań po zabiegu ESWL może być „droga kamieni”. Po wykonaniu zabiegu ESWL pacjent wymaga monitorowania poprzez wykonywanie badań USG, co pozwala na szybkie uwidocznienie powikłania w postaci „drogi kamieni” i wdrożenie dodatkowego postępowania ułatwiającego wydalenie złogów. „Droga kamieni” może spowodować utrudnienie odpływu moczu, co może być przyczyną dolegliwości bólowych oraz różnego stopnia poszerzeń moczowodów i układów kielichowo-miedniczkowych. Często wymaga interwencji zabiegowej w trybie pilnym. W ciągu ostatnich dwudziestu lat nastą- piły w Polsce znaczne zmiany w sposobach leczenia kamicy moczowodowej. Rutynowo stosuje się URSL i ESWL, do rzadkości natomiast należy zak

Mitos da didática das ciências acerca dos motivos para incluir a Natureza da Ciência no ensino das ciências Science Education myths about the reasons to include the Nature of Science in science teaching

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J. A. Acevedo

2005-04-01

Full Text Available Em certas situações, a Didática das Ciências transmite como mitos algumas crenças que não estão suficientemente sustentadas pela investigação que ela própria produz. Este artigo mostra dois desses mitos relacionados com os motivos que se costumam apontar para incluir a Natureza da Ciência no ensino das ciências, como sejam a suposta relação entre a prática docente e as crenças sobre a Natureza da Ciência, e a crença de que a sua compreensão é um fator chave na hora de tomar melhores decisões cívicas em questões tecnocientíficas de interesse social. A análise que se apresenta realizou-se mediante a revisão de diversos resultados de investigações procedentes da própria Didática das Ciências e também da Psicologia das Decisões. A conclusão aponta para considerar que outros fatores influenciam mais, tornando muito menos lineares essas hipotéticas relações do que alguns especialistas pensam e mais complexa a problemática abordada.In some situations Science Education transmits as myths various beliefs as myths that are not enough sustained by the research in its own domain. This paper shows two of these myths related to the reasons usually pointed in orderfor includinge the Nature of Science in science teaching:, such as the supposed relationship between the educational practice and the beliefs about the Nature of Science, and also the belief that its understanding of the Nature of Science is a key factor in when making better civicdecisions as citizens in technical socioscientific oscientific issues. with social interest The analysis was carried out by means of athe review of several results from the own Science Education Research, and also from the Psychology of Decisions. The conclusion seems to be clear: other factors are of a greater influence, making those hypothetical relations much less linear than some experts wcould think, and making the questions much more complex. the presented question.

Evaluation of radioiodine therapy with fixed doses of 10 and 15 mCi in patients with Graves disease; Avaliacao da radioiodoterapia com doses fixas de 10 e 15 mCi em pacientes com doenca de Graves

Energy Technology Data Exchange (ETDEWEB)

Canadas, Viviane; Vilar, Lucio; Moura, Eliane; Brito, Ana; Castellar, Enio [Universidade Federal de Pernambuco (UFPE), Recife, PE (Brazil). Hospital das Clinicas. Servico de Endocrinologia]. E-mail: vivi2207@ig.com.br

2007-10-15

The treatment options for the hyperthyroidism of Graves' disease are antithyroid drugs, surgery and radioiodine, none of which is considered ideal, as they do not act directly on the etiopathogenesis of the disease. Radioiodine has been increasingly used as the treatment of choice because it is a safe and definitive therapy whose administration is very easy. Some authors prefer to administer higher doses in order to deliberately induce hypothyroidism, while others recommend lower doses that result in a lower incidence of hypothyroidism and a greater incidence of euthyroidism. There is no consensus for the optimal regimen of fixed doses to be used and this is the main focus of the present study, where doses of 10 and 15 mCi of {sup 131}I were compared. Among the 164 patients analyzed, 61 (37.2%) were submitted to 10 mCi and 103 (62.8%) to 15 mCi. In the longitudinal analysis it was observed that remission of the hyperthyroidism was statistically different in the sixth month (p < 0.001), being higher in the group that used the dose of 15 mCi, but similar in both groups at 12 and 24 months. It may be concluded that the administration of fixed doses of 10 and 15 mCi of {sup 131}I brought about a similar remission of the hyperthyroidism after 12 months of treatment. Moreover, the remission rate of the hyperthyroidism had no association with age, sex or previous therapy with antithyroid drugs. (author)

Lifetime broadening and CI-resonances observed in ESCA

International Nuclear Information System (INIS)

Svensson, S.; Maartensson, N.; Basilier, E.; Malmquist, P.Aa.; Gelius, U.; Siegbahn, K.

1976-03-01

The electron spectrum of the M 2 and M 3 levels in bromine and krypton have been studied by high resolution ESCA. The M 1 Msub(2,3) super Coster-Kronig transitions become energetically forbidden for Z >approximately 36 (Kr) and recent calculations therefore predict a decrease in the M 2 and M 3 natural linewidths around krypton in the periodic system. The experiment shows that the 3psub(3/2) linewidth is smaller in Kr than in Br. It is, however, also found that this decrease in linewidth is followed by configuration interaction (CI) between 3p 2 P and 3d 2 nl * 2 P states. Several discrete CI resonances are observed in the Kr 3p spectrum. Such resonances are also studied in the N shell for the elements from Te(Z=52) to Ba(Z=56). For these elements the effect is found to be much larger due to the strong collective character of 4d-nf* excitations. (Auth.)

FUNKCJA SUM HARMONICZNYCH W SKRÓCONEJ PROCEDURZE OZNACZANIA ZESPOLONEGO MODUŁU SZTYWNOŚCI MMA

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Andrzej POŻARYCKI

2016-07-01

Full Text Available W standardowej procedurze oznaczania sztywności mieszanek mineralno-asfalto-wych w funkcji częstotliwości obciążenia, powszechnie stosuje się metodę badań próbek obciążonych serią funkcji sinusoidalnych. W zależności od przyjętego wachlarza deklarowanych przez laboranta częstotliwości, procedura z serią badań stanowi procedurę inwazyjną, zwiększając jednocześnie prawdopodobieństwo wystąpienia zjawisk zmęczeniowych w badanych próbkach podczas realizowania testu. W pracy, w miejsce powszechnie stosowanej procedury zaproponowano obciążenie w formie funkcji utworzonej jako sumy funkcji harmonicznych. Na podstawie analizy wyników badań sztywności próbki belkowej wykazano, że proponowane podejście wyraźnie skraca czas procedury oznaczania zespolonego modułu sztywności, a różnice między standardowym ujęciem a tym proponowanym w pracy są w przeważającej większości mniejsze niż 2 %.

Eclipse in the binary system of the CI Cyg symbiotic star

Energy Technology Data Exchange (ETDEWEB)

Belyakina, T S

1979-01-01

Photoelectric photometry and spectral observations of the symbiotic star CI Cyg were carried out at the Crimean Astrophysical Observatory from April, 1975 through December, 1976. The instrumental photometric system used was close to the UBV. Considerable light variations and spectral changes have been recorded during the period of the observations. Yellow, blue and ultraviolet amplitudes were equal to 2.3, 3.0 and 3sub(m).3 correspondingly. The brightness of CI Cyg reached maximal value in June - July, 1975 when spectrum was F5 with Hsub(..cap alpha..) and Hsub(..beta..) in emission. A sharp and deep minimum in the light curves of CI Cyg was observed during the period of the highest brightness. It was caused by the eclipse of the hot component by the cold one in the binary system.

Aktywność fizyczna w terapii otyłości

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Joanna Zapolska

2009-03-01

Full Text Available Otyłość jest chorobą określaną jako patologiczne zwiększenie ilości tkanki tłuszczowej, która w nadmiernej ilości wpływa negatywnie na stan zdrowia, długość życia i sprawność psychofizyczną. Osoby z nadmierną masą ciała, w której zawartość tłuszczu stanowi proporcjonalnie wysoki odsetek, w porównaniu z osobami o niższej masie ciała są fizjologicznie mniej wydolni, a ich potencjał motoryczny jest niższy. W otyłości u osób dorosłych dochodzi przede wszystkim do zwiększenia rozmiarów komórek tłuszczowych. W przypadku dzieci obserwujemy przyrost liczby komórek tłuszczowych, które mogą się przyczynić do rozwoju otyłości w wieku dorosłym, gdyż zwiększenie liczby komórek jest procesem nieodwracalnym. Często rodzice aż do momentu wystąpienia znacznej otyłości nie postrzegają nadmiernej masy ciała dziecka w kategoriach problemu zdrowotnego. Istotna staje się więc rola służby zdrowia w prowadzeniu działań prewencyjnych, skierowanych na działania np. fitness clubów odpowiednio przygotowanych do podejmowania tego typu zadań. Ogólnie przyjęte zasady dawkowania ćwiczeń w treningu zdrowotnym fitness osób dorosłych oraz dzieci i młodzieży są podobne. Różnią się czasem trwania, częstotliwością podejmowania aktywności oraz stosowanymi obciążeniami. Treningi fitness obejmują głównie wytrzymałościowe formy ćwiczeń, takie jak ćwiczenia aerobowe na urządzeniach typu cardio mające za zadanie przede wszystkim uaktywnić i zredukować nadmiar tkanki tłuszczowej. Inną formą zajęć usprawniających powinny być ćwiczenia oporowe uwzględniające stosowanie urządzeń izotonicznych. Należy przy tym zwrócić szczególną uwagę na dobór ćwiczeń, obciążenie oraz kontrolę postępów. Równocześnie zaleca się stosowanie monitoringu zakresów HR każdej sesji treningu aerobowego i oporowego. Jako uzupełnienie proponowane są ćwiczenia gibkościowe wykonywane jako �

Cast iron (CI) based soft magnetic BMG Ci{sub 88.3}Al{sub 2}Ga{sub 1}P{sub 4.35}B{sub 4.35}

Energy Technology Data Exchange (ETDEWEB)

Kane, S N; Lee, H J; Jeong, Y H [Department of Physics, Pohang University of Science and Technology (POSTECH), 790-784 Pohang (Korea, Republic of); Varga, L K, E-mail: varga@szfki.h [RISSPO, Hungarian Academy of Sciences, PO Box 49, 1525 Budapest (Hungary)

2009-01-01

Thermal stability, structure, and magnetic properties of bulk type Ci{sub 88.3}Al{sub 2}Ga{sub 1}P{sub 4.35}B{sub 4.35} alloy in ribbon form have been studied using differential thermal analysis, x-ray diffraction and magnetic measurements. Results reveal that crystallization peak temperature (T{sub x}) and Curie temperature (T{sub c}) of the as-cast alloy are respectively 513 and 370 deg. C. Crystallization of the specimen starts after annealing at 460 deg. C and alpha-Fe is precipitated out. Annealing at temperatures higher than 515 deg. C, produces apart from alpha-Fe, hard magnetic precipitants (Fe{sub 2}B, Fe{sub 3}B), which deteriorate the soft magnetic properties. Lowest coercive field - 9.8 A/m, highest saturation of induction - 1.55 Tesla and best losses - 0.42 W/kg (at 50 Hz and 0.4 kA/m) were obtained for as-cast specimen. Observed good soft magnetic properties of these low cost cast-iron based alloys suggest perspective applications of these soft magnetic alloys as an alternative to the conventional Fe-Si electrical steel and Mn-Zn ferrites.

Preparation of 1 Ci of europium 155 without carrier

International Nuclear Information System (INIS)

Falconi, N.; Radicella, R.

1968-01-01

High activity 'point' sources of 155 Eu are used for medical and industrial applications. For this purpose we have studied a method of obtaining I Ci of carrier free 155 Eu, with a solid residue smaller than 5 mg per Ci. In order to separate the 155 Eu from several grams of a 154 Sm enriched target we propose a procedure which is based on the work of Bouissieres and David, Onstott, and Takekoshi et al. The separation is carried out by electrolysis on a mercury cathode followed by purification on ion exchange resin. The yields of the europium separation and target recovery are 80 per cent and 90 per cent respectively. The time required for the procedure is three days. (authors) [fr

Electro-chemical coupling in the voltage-dependent phosphatase Ci-VSP

Science.gov (United States)

Kohout, Susy C.; Bell, Sarah C.; Liu, Lijun; Xu, Qiang; Minor, Daniel L.; Isacoff, Ehud Y.

2010-01-01

In the voltage sensing phosphatase, Ci-VSP, a voltage sensing domain (VSD) controls a lipid phosphatase domain (PD). The mechanism by which the domains are allosterically coupled is not well understood. Using an in vivo assay, we find that the inter-domain linker that connects the VSD to the PD is essential for coupling the full-length protein. Biochemical assays show that the linker is also needed for activity in the isolated PD. We identify a late step of VSD motion in the full-length protein that depends on the linker. Strikingly, this VSD motion is found to require PI(4,5)P2, a substrate of Ci-VSP. These results suggest that the voltage-driven motion of the VSD turns the enzyme on by rearranging the linker into an activated conformation, and that this activated conformation is stabilized by PI(4,5)P2. We propose that Ci-VSP activity is self-limited because its decrease of PI(4,5)P2 levels decouples the VSD from the enzyme. PMID:20364128

sobre la calidad del agua de la ciénaga

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Diego Alejandro Chalarca Rodríguez

2007-01-01

Full Text Available En el municipio de Ayapel, departamento de Córdoba, se realizaron cuatro muestreos de campo con el fin de obtener información representativa de las variaciones horarias del agua residual del municipio como también de la calidad del agua en la zona de influencia de éstas en la ciénaga de Ayapel. En el sector donde se presentan las principales descargas del alcantarillado se determinaron las variables fisicoquímicas y microbiológicas del agua residual doméstica y de la ciénaga. Ello con el fin de determinar el posible impacto de las aguas residuales domésticas sobre la calidad del agua de un sector de la ciénaga de Ayapel.Los resultados del estudio permiten afirmar que existe un impacto de las aguas residuales sobre el complejo cenagoso, sin embargo estas descargas afectan principalmente la calidad ambiental de los sitios aledaños al casco urbano del municipio de Ayapel, principalmente en las épocas de aguas bajas incluyendo la zona pelágica del sector E0.

A concepção de ciência de Popper e o ensino de ciências Popper's conception of science and the teaching of sciences

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Carlos Alberto Rufatto

2009-01-01

Full Text Available Procurou-se identificar as consequências mais importantes da concepção de ciência de Popper, que deu origem a um rico debate na Filosofia das Ciências, para o Ensino de Ciências. O acompanhamento deste debate permite perceber a riqueza do processo científico, reconhecendo as contribuições daqueles que debateram com Popper; bem como a importância dos aspectos da ciência que Popper valorizou e procurou preservar. As críticas e os debates em torno das abordagens de mudança conceitual contribuíram para a percepção da riqueza e complexidade desse processo. Quando considerados os objetivos institucionais das escolas e as expectativas sociais em torno da compreensão adequada e da procura de superação dos paradigmas vigentes a manutenção de certos aspectos, inerentes ao processo de mudança conceitual, pode se mostrar relevante. Neste sentido, a obra de Popper pode oferecer importante apoio para valorizar aspectos racionais que poderiam presidir o processo de aprender Ciências.This work aimed at identifying the most important consequences of Popper's conception of science education, which started a fertile debate in the Philosophy of Science. By following this debate, it is possible to notice the richness of the cientific process, recognizing the contributions brought by those who debated with Popper, and the importance of aspects of science that Popper valued and attempted to preserve. The criticism and the debate over the approaches towards conceptual change contributed to the perception of the wide extent and complexity of this process. However, the maintenance of certain aspects, inherent in the process of conceptual change, may be relevant when the institutional objectives of the schools and the social expectations over the appropriate understanding and over the attempt to overcome current paradigms are considered. In this way, Popper's work may offer important support to valuing rational aspects that could inform the process

Expression, purification, and reconstitution of the voltage-sensing domain from Ci-VSP.

Science.gov (United States)

Li, Qufei; Jogini, Vishwanath; Wanderling, Sherry; Cortes, D Marien; Perozo, Eduardo

2012-10-16

The voltage-sensing domain (VSD) is the common scaffold responsible for the functional behavior of voltage-gated ion channels, voltage sensitive enzymes, and proton channels. Because of the position of the voltage dependence of the available VSD structures, at present, they all represent the activated state of the sensor. Yet in the absence of a consensus resting state structure, the mechanistic details of voltage sensing remain controversial. The voltage dependence of the VSD from Ci-VSP (Ci-VSD) is dramatically right shifted, so that at 0 mV it presumably populates the putative resting state. Appropriate biochemical methods are an essential prerequisite for generating sufficient amounts of Ci-VSD protein for high-resolution structural studies. Here, we present a simple and robust protocol for the expression of eukaryotic Ci-VSD in Escherichia coli at milligram levels. The protein is pure, homogeneous, monodisperse, and well-folded after solubilization in Anzergent 3-14 at the analyzed concentration (~0.3 mg/mL). Ci-VSD can be reconstituted into liposomes of various compositions, and initial site-directed spin labeling and electron paramagnetic resonance (EPR) spectroscopic measurements indicate its first transmembrane segment folds into an α-helix, in agreement with the homologous region of other VSDs. On the basis of our results and enhanced relaxation EPR spectroscopy measurement, Ci-VSD reconstitutes essentially randomly in proteoliposomes, precluding straightforward application of transmembrane voltages in combination with spectroscopic methods. Nevertheless, these results represent an initial step that makes the resting state of a VSD accessible to a variety of biophysical and structural approaches, including X-ray crystallography, spectroscopic methods, and electrophysiology in lipid bilayers.

Expression, Purification and Reconstitution of the Voltage Sensing Domain from Ci-VSP

Science.gov (United States)

Li, Qufei; Jogini, Vishwanath; Wanderling, Sherry; Cortes, D. Marien; Perozo, Eduardo

2013-01-01

The voltage-sensing domain (VSD) is the common scaffold responsible for the functional behavior of voltage gated ion channels, voltage sensitive enzymes and proton channels. Because of the position of the voltage dependence of the available VSD structures, at present, they all represent the activated state of the sensor. Yet, in the absence of a consensus resting state structure, the mechanistic details of voltage sensing remain controversial. The voltage dependence of the VSD from Ci-VSP (Ci-VSD) is dramatically right shifted, so that at 0 mV It presumably populates the putative resting state. Appropriate biochemical methods are an essential prerequisite to generate sufficient amounts of Ci-VSD protein for high-resolution structural studies. Here, we present a simple and robust protocol for the Escherichia coli expression of eukaryotic Ci-VSD at milligram levels. The protein is pure, homogeneous, mono-disperse and well folded after solubilization in Anzergent 3-14 at the analyzed concentration (~ 0.3 mg/mL). Ci-VSD can be reconstituted into liposomes of various compositions and initial site-directed spin labeling and EPR spectroscopic measurements indicate its first transmembrane segment folds into an α-helix, in agreement to the homologous region of other VSDs. Based on current results and enhanced relaxation EPR spectroscopy measurement, Ci-VSD reconstitutes essentially randomly in proteo-liposomes, precluding straightforward application of transmembrane voltages in combination with spectroscopic methods. Nevertheless, the present results represent an initial step that makes the resting state of a VSD accessible to a variety of biophysical and structural approaches, including X-ray crystallography, spectroscopic methods and electrophysiology in lipid bilayers. PMID:22989304

CiOpt: a program for optimization of the frequency response of linear circuits

OpenAIRE

Miró Sans, Joan Maria; Palà Schönwälder, Pere

1991-01-01

An interactive personal-computer program for optimizing the frequency response of linear lumped circuits (CiOpt) is presented. CiOpt has proved to be an efficient tool in improving designs where the inclusion of more accurate device models distorts the desired frequency response, as well as in device modeling. The outputs of CiOpt are the element values which best match the obtained and the desired frequency response. The optimization algorithms used (the Fletcher-Powell and Newton's methods,...

Contribuições para o estudo do ciúme excessivo

OpenAIRE

Andrea Lorena da Costa

2010-01-01

O ciúme romântico é um complexo de pensamentos, emoções e ações que visam proteger o relacionamento diante de uma ameaça percebida real ou imaginária e tem como objetivo eliminar os riscos da perda do objeto de amor. O ciúme excessivo (patológico) é uma preocupação infundada, irracional e irreal, composto de diversas emoções e pensamentos que provocam prejuízos significativos no funcionamento pessoal e relacional. O objetivo deste trabalho foi explorar a presença de transtornos psiquiátrico...

Effect of Inhomogeneous Mixture Properties on CI Combustion in a Schnurle-Type Gasoline DI Engine

Science.gov (United States)

Kim, Seok-Woo; Moriyoshi, Yasuo

The authors have performed experiments on compression-ignition (CI) for a single-cylinder Schnurle-type two-stroke gasoline direct injection (DI) engine which employs a variable exhaust port, area, and deduced two presumptions from the experimental results. Firstly, the spatial distributions of fuel concentration and in-cylinder gas temperature are indispensable to enable CI operation under stratified charge conditions, because CI operation is not possible in a DI system although the necessary conditions of the scavenging efficiency and the in-cylinder gas temperature for the initiation of CI in homogeneous charge conditions are satisfied. Secondly, it is possible that flame propagation occurs in stratified charge CI conditions, because the combustion period in the later stage after 80% mass burned becomes longer than that with homogeneous charge CI combustion. In this report, in order to verify the above two presumptions deduced from experiments, the gas exchange process and mixture formation process were numerically analyzed, and the initiation conditions of CI were estimated using a CHEMKIN application. As a result, in case of CI with a late injection timing in DI system, it was found that CI was possible because high temperature but no fuel region and low temperature but rich fuel region exist in the cylinder due to inhomogeneous spatial distributions of fuel and temperature. Also, in case of CI with a late injection timing, the flame propagation was possible in the low-temperature and diluted rich region. Thereby, the two presumptions deduced from the experimental results were validated from the numerical analysis results.

Calculation of particle dynamics in CI-10 cyclotron

International Nuclear Information System (INIS)

Samsonov, E.V.; Karamysheva, G.A.; Vorozhtsov, S.B.

1999-01-01

The calculations of beam dynamic characteristics of High-Intensity Cyclotron-Injector CI-10 for deuteron beam of 15 MeV energy are presented. Analytical estimations of space charge effects are given. In order to increase the intensity of the accelerator beam some ideas about the cyclotron design modification are given too. (author)

Notas sobre o autotelismo discursivo em ciências humanas

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Paulo Eduardo Lopes

1994-12-01

Full Text Available O Ateliê de Semiótica Discursiva, coordenado por Denis Bertrand, propôs focalizar, no ano letivo 1991-1992, a " Estética do Discurso Erudito", no quadro da temática "Estética da Ética" do Seminário de Semântica Geral, de A.J . Greimas, na Escola de Altos Estudos em Ciências Sociais de Paris (E. H. E. S. S.. Bertrand distribuiu cópias de trechos de textos célebres em ciências humanas (Lévi-Strauss, Deleuze e Guattari, Greimas, Barthes, Foucault e outros, sobre os quais os participantes deveriam realizar análises que tomassem como modelo, por exemplo, aquelas praticadas por Greimas e Landowski em lntroduction à L 'Analyse du Discours en Sciences Sociales ( 1979.

An Experimental Research on the pCI Rule and Causal Judgment (in Chinese)

OpenAIRE

Shao, Z. F.; Wang, J.

2005-01-01

This research examined the precision of the pCI rule through three experiments. The results show that first , the tendency of the subjects’ casual judgments was basically similar to the pCI rule. But (a + d) / n predicted human’s casual judgments were even better; second, the increase of subjects’ casual judgments was milder than the pCI rule, and the subjects needed time to construct their own way of judging relationship; finally, different people had different ways of causal judgments, and ...

OCENA WŁAŚCIWOŚCI PRZECIWPOŚLIZGOWYCH NAWIERZCHNI DROGOWYCH PRZY WYKORZYSTANIU URZĄDZEŃ TWO, CTM I DFT

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Marta WASILEWSKA

2016-07-01

Full Text Available Kompleksowa ocena właściwości przeciwpoślizgowych powinna być wykonywana w oparciu o ciągły pomiar współczynnika tarcia oraz parametrów dotyczących tekstury nawierzchni drogowych. W artykule przedstawiono ocenę właściwości przeciwpoślizgowych nawierzchni drogowych przeprowadzoną na podstawie pomiarów wykonanych zestawem pomiarowym TWO (Traction Watcher One oraz urządzeniami CTM (Circular Track Meter i DFT (Dynamic Friction Tester. Do badań wytypowano 11 odcinków testowych, których warstwy ścieralne były zróżnicowane pod względem technologii wykonania, okresu użytkowania i obciążenia ruchem samochodowym. Przy pomocy urządzenia CTM dokonano oceny makrotekstury (parametr MPD, a przy wykorzystaniu urządzenia DFT oceniano w sposób pośredni mikroteksturę powierzchni (współczynnik tarcia DFT20. Urządzenie TWO umożliwiło ciągły pomiar współczynnika tarcia z ustalonym poślizgiem 17,8% koła pomiarowego przy trzech prędkościach 30, 60, 90 km/h. W artykule ustalono zależności funkcyjne pomiędzy współczynnikiem tarcia µ z pomiarów TWO, a współczynnikiem DFT20 i parametrem MPD. Wykazano, że na wartość µ przy prędkości 30 km/h istotny wpływ ma jedynie mikrotekstura nawierzchni, a przy prędkości 60 i 90 km/h zarówno mikrotekstura i makrotekstura.

Przyczynek do postrzegania struktury współczesnego systemu rachunkowości

Directory of Open Access Journals (Sweden)

Irena Sobańska

2018-03-01

Full Text Available Głównym celem artykułu jest objaśnienie procesu ewoluowania elementów systemu rachunkowości organizacji gospodarczej pod wpływem zmian zachodzących w różnicach informacji oczekiwanych przez odbiorców wewnętrznych i zewnętrznych. Dla zrealizowania tego celu przedstawiono zamęt regu- lacyjny w obszarze rachunkowości i jego skutki dla rozwoju systemów rachunkowości w praktyce w Polsce oraz przeanalizowano zmiany w potrzebach informacyjnych interesariuszy w kontekście wprowadzanych zmian w sprawozdaniach finansowych, zintegrowanych raportach biznesowych i zmian w stosowanych metodach rachunkowości zarządczej w organizacjach społecznie odpowiedzialnych. Następnie przedsta- wiona została autorska propozycja nowej struktury systemu rachunkowości odpowiadająca jego współczesnej funkcjonalności w warunkach obecnego poziomu rozwoju globalizacji, zmierzającego w kierun- ku zrównoważonej gospodarki oraz szereg wniosków ogólnych wynikających z przedstawionych rozwa- żań. W propozycji nowej struktury przyjęto, że system rachunkowości organizacji społecznie odpowie- dzialnej powinien być zbudowany z podsystemu rachunkowości biznesowej, emitującego zintegrowany raport biznesowy (sprawozdanie finansowe + raporty niefinansowe i wewnętrzne raporty dla zarządu oraz podsystemu rachunkowości podatkowej, emitującego informacje dla agend podatkowych. W opra- cowaniu artykułu zastosowano analizę treści i opinii autorów wybranych publikacji, metodę analizy dokumentów oraz wiedzę uzyskaną metodą obserwacji bezpośredniej i wyniki badań empirycznych innych autorów. The main goal of the article is to explain the process of evolution of the organization's accounting system elements as a result of changes taking place in information expected by internal and external users. To achieve this goal, regulatory uncertainties in the area of accounting and their consequences for the devel- opment of accounting systems in

Rola otyłości w patogenezie chorób alergicznych

Directory of Open Access Journals (Sweden)

Anna Grad

2009-09-01

Full Text Available W ostatnich latach wzrosła zachorowalność na astmę i inne choroby alergiczne. Jednocześnie obserwuje się zwiększenie liczby pacjentów z nadmierną masą ciała i podwyższoną wartością wskaźnika wagowo-wzrostowego (BMI. Wydaje się, że mimo odmiennego patomechanizmu astmy i otyłości istnieje wspólne ogniwo patogenetyczne rozwoju tych chorób. Bierze się pod uwagę rolę czynników środowiskowych, dietetycznych, genetycznych i infekcyjnych. Wyniki większości badań epidemiologicznych potwierdzają związek nadwagi i otyłości z ryzykiem wystąpienia astmy zarówno u osób dorosłych, jak i u dzieci. Podkreśla się rolę wysokiej urodzeniowej masy ciała i większych przyrostów masy ciała w pierwszym roku życia. Natomiast występowanie alergicznego nieżytu nosa i alergicznego zapalenia spojówek koreluje ujemnie z masą ciała. Nie obserwowano związku otyłości z częstością występowania atopowego zapalenia skóry. Tkanka tłuszczowa jako narząd endokrynny produkuje dużo różnych cytokin, hormonów, czynników wzrostu. Jest źródłem czynników prozapalnych, między innymi IL-6, TNF-a, TGF-b, leptyny, rezystyny. Leptyna jest produkowana przez adipocyty, jej stężenie koreluje z masą tkanki tłuszczowej, może ona intensyfikować zapalenie oraz odgrywać ważną rolę w rozwoju płuc. Podwyższone stężenie leptyny w surowicy jest uważane za czynnik prognostyczny rozwoju astmy. Adiponektyna ma właściwości przeciwzapalne, jej stężenie maleje w otyłości i koreluje ujemnie ze wskaź- nikiem BMI. W rozwoju astmy u osób otyłych biorą również udział rezystyna, eotaksyna, białko aP2 oraz żeńskie hormony płciowe. Rola czynników genetycznych nie jest do końca poznana. Dotychczas wyodrębniono 4 regiony chromosomalne związane ze zwiększoną podatnością na zachorowanie na astmę i otyłość. Efekt ochronny mają czynniki dietetyczne, takie jak antyoksydanty i mikroelementy. Otyłość pogarsza

Rola otyłości w patogenezie chorób alergicznych

Directory of Open Access Journals (Sweden)

Anna Grad

2008-10-01

Full Text Available W ostatnich latach wzrosła zachorowalność na astmę i inne choroby alergiczne. Jednocześnie obserwuje się zwiększenie liczby pacjentów z nadmierną masą ciała i podwyższoną wartością wskaźnika wagowo-wzrostowego (BMI. Wydaje się, że mimo odmiennego patomechanizmu astmy i otyłości istnieje wspólne ogniwo patogenetyczne rozwoju tych chorób. Bierze się pod uwagę rolę czynników środowiskowych, dietetycznych, genetycznych i infekcyjnych. Wyniki większości badań epidemiologicznych potwierdzają związek nadwagi i otyłości z ryzykiem wystąpienia astmy zarówno u osób dorosłych, jak i u dzieci. Podkreśla się rolę wysokiej urodzeniowej masy ciała i większych przyrostów masy ciała w pierwszym roku życia. Natomiast występowanie alergicznego nieżytu nosa i alergicznego zapalenia spojówek koreluje ujemnie z masą ciała. Nie obserwowano związku otyłości z częstością występowania atopowego zapalenia skóry. Tkanka tłuszczowa jako narząd endokrynny produkuje dużo różnych cytokin, hormonów, czynników wzrostu. Jest źródłem czynników prozapalnych, między innymi IL-6, TNF-a, TGF-b, leptyny, rezystyny. Leptyna jest produkowana przez adipocyty, jej stężenie koreluje z masą tkanki tłuszczowej, może ona intensyfikować zapalenie oraz odgrywać ważną rolę w rozwoju płuc. Podwyższone stężenie leptyny w surowicy jest uważane za czynnik prognostyczny rozwoju astmy. Adiponektyna ma właściwości przeciwzapalne, jej stężenie maleje w otyłości i koreluje ujemnie ze wskaź- nikiem BMI. W rozwoju astmy u osób otyłych biorą również udział rezystyna, eotaksyna, białko aP2 oraz żeń- skie hormony płciowe. Rola czynników genetycznych nie jest do końca poznana. Dotychczas wyodrębniono 4 regiony chromosomalne związane ze zwiększoną podatnością na zachorowanie na astmę i otyłość. Efekt ochronny mają czynniki dietetyczne, takie jak antyoksydanty i mikroelementy. Otyłość pogarsza

ANALIZA PRACY INSTALACJI FOTOWOLTAICZNEJ W ZALEŻNOŚCI OD ORIENTACJI GEOGRAFICZNEJ

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Ewelina KRAWCZAK

Full Text Available Rynek odnawialnych źródeł energii z każdym dniem coraz bardziej się rozwija. Zapotrzebowanie na energię elektryczną wzrasta, przy czym zasoby konwencjonalnych i zarazem nieodnawialnych źródeł energii (paliw kopalnych ulegają zubożeniu. Alternatywą dla nich są odnawialne źródła energii (OZE, których rezerwy uzupełniane są w naturalnych procesach ekosystemu, co stanowi o ich niewyczerpalności. Zmiany legislacyjne w Polsce dotyczące OZE spowodowały duże zainteresowanie małymi instalacjami fotowoltaicznymi w wyniku czego dotychczasowy konsument zmienia się w prosumenta energii elektrycznej. Rozwój rynku odnawialnych źródeł energii stawia przed projektantami ciągłe wyzwania, ponieważ projektowanie instalacji fotowoltaicznych o wysokiej wydajności dla istniejących budynków, przy uwzględnieniu występujących lokalnych warunków oraz architektury budowli, jest niezwykle trudne. Uzysk energetyczny systemu słonecznego zależy od wielu czynników, jednym z najważniejszych jest wartość nasłonecznienia zależna od lokalizacji (szerokości geograficznej, a także orientacja projektowanego systemu względem kierunku azymutu. Narzędziem wspomagającym i usprawniającym projektowanie instalacji PV (Photovoltaics jest oprogramowanie DDS-CAD, pozwalające przeprowadzić symulację uzysków energii elektrycznej. Wyniki otrzymanych symulacji umożliwiają w krótkim czasie porównanie wielu wirtualnych modeli instalacji pod kątem wydajności, a co za tym idzie wybranie najkorzystniejszego wariantu dla istniejącej orientacji geograficznej. W niniejszej pracy poddane zostały analizie rezultaty symulacji wirtualnych modeli instalacji fotowoltaicznych pod względem liczby generatorów fotowoltaicznych oraz wielkości uzysku energii elektrycznej przy założeniu wykorzystania całej powierzchni dachu oraz uwzględnieniu zmiany kąta usytuowania modułów PV względem okapu połaci dachowej i kierunku azymutu.

Badania jakości regeneratu ze zużytych mas ze spoiwem organicznym

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R. Dańko

2012-12-01

Full Text Available W publikacji przedstawiono uzupełniające metody badań oraz aparaturę do oceny jakości regeneratu i tych właściwości masformierskich ze spoiwami utwardzanymi chemicznie, przygotowywanych z regeneratem, które są istotne dla kompleksowej oceny procesurecyklingu osnowy. Nowoczesne systemy oceny mas formierskich wymagają bardziej wnikliwego podejścia do czynników decydującychzarówno o ich przydatności technologicznej jak również o wpływie na otaczające środowisko naturalne. W tym kontekście pełna ocenajakości zregenerowanej osnowy wykracza poza zwyczajowo stosowane metody instrumentalne i wymaga ich uzupełnienia o bardziejzaawansowane aparaturowo metody badawcze. Pozwala to szerzej spojrzeć na ocenę zregenerowanej osnowy, zarówno w aspekcie jejużycia do sporządzania mas formierskich, jako substytutu świeżego piasku, ale także pod kątem ochrony środowiska. Do takichnowoczesnych metod można zaliczyć między innymi analizę ziarnową regeneratu za pomocą dyfrakcji laserowej, a także ocenęgazotwórczości masy formierskiej oraz identyfikację rodzaju emitowanych gazów i zawartości w nich gazów z grupy BTEX, które sąszczególnie niebezpieczne z punktu widzenia BHP.

Część I – ocena okoliczności i biomechaniki urazu

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Grzegorz Teresiński

2014-10-01

Full Text Available Badania nad etiologią i zapobieganiem dystorsji kręgosłupa szyjnego pozostają od wielu lat w centrum zainteresowania badaczy związanych z przemysłem samochodowym i medycyną wypadkową, a także towarzystw ubezpieczeniowych. Etiopatogeneza zespołu dolegliwości związanych z tzw. whiplash (WAD budzi wciąż kontrowersje i jak dotychczas nie udało się w jednoznaczny sposób ustalić jego morfologicznych wykładników. Subiektywny charakter skarg powoduje bardzo duże trudności w obiektywizacji następstw urazu akceleracyjno- deceleracyjnego oraz weryfikacji zgłaszanych roszczeń. Celem pracy było przedstawienie  zależności biomechanicznych oraz okoliczności towarzyszących powstawaniu WAD wynikających z badań populacyjnych, statystyk firm ubezpieczeniowych oraz analizy zapisów rejestratorów zderzeń montowanych przez producentów samochodów. Znajomość technicznych aspektów okoliczności powstawania WAD może ułatwić medyczną ocenę tego rodzaju następstw.

Testy czynnoœci płuc i nadreaktywnoœæ oskrzeli w astmie

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Iwona Grzelewska-Rzymowska

2009-09-01

Full Text Available Astma jest chorobą, która charakteryzuje się odwracalną obturacją oskrzeli i postępującym spadkiem wskaźników wentylacji. Podstawową rolę w rozpoznawaniu astmy odgrywają badania spirometryczne z oznaczeniem podstawowych wartości natężonej pojemności życiowej (FVC i natężonej objętości wydechowej 1-sekundowej (FEV1 oraz wynikiem testu odwracalności obturacji oskrzeli. W monitorowaniu przebiegu astmy zaleca się oznaczanie wskaźnika określanego jako szczytowy przepływ wydechowy (PEF, jednak jego czułość jest mniejsza niż wskaźnika FEV1. Fundamentalną cechą astmy jest nadreaktywność oskrzeli, która wskazuje na większy stopień odpowiedzi oskrzeli osób chorych niż zdrowych. Nadreaktywność oskrzeli można określić, stosując wziewne testy prowokacyjne z bronchospastycznymi substancjami (histaminą, metacholiną, 5-AMP. U dzieci bardzo użyteczny jest test wysiłkowy, który charakteryzuje się dużą swoistością, ale małą czułością. Leczenie astmy poprawia jej kliniczny przebieg, jak również wskaźniki wentylacji, które pozwalają określić także stopień zaawansowania choroby. U chorych z przebudową oskrzeli nie obserwuje się wzrostu wskaźników wentylacji. Przebudowa oskrzeli powoduje nieodwracalną obturację i jest typowa dla chorych o ciężkim przebiegu tej choroby. W ciężkiej astmie ujemny wynik daje też test odwracalności obturacji oskrzeli, podobnie uzyskuje się niskie wartości PEF. Nadreaktywność oskrzeli jest użyteczna w procesie diagnozowania astmy. Jej wartość łączy się z zapaleniem alergicznym oskrzeli oraz wskaźnikami wentylacji. Leczenie poprawia przebieg kliniczny choroby i wskaźniki wentylacji, jednak nie wpływa na nadreaktywność oskrzeli.

A ciência e a tecnologia para os estudantes brasileiros : percepções

OpenAIRE

da Cunha, Marcia Borin

2013-01-01

Nos anos de 2010 e 2011 realizamos uma pesquisa nacional para verificar as percepções dos estudantes brasileiros sobre temas relacionados à ciência e tecnologia. Esta investigação buscou averiguar como os jovens em idade escolar (Ensino Médio) percebem a ciência e a tecnologia em suas vidas, considerando-se que estas percepções têm influencia na formação dos conceitos científicos escolares e na forma como os jovens relacionam-se com a ciência (Teoria Sociocultural de Vygotsky). Os resultados ...

Qual ciência na educação não formal? Com a palavra as exposições e a divulgação na internet de museus e centros de ciências brasileiros.

OpenAIRE

Figueirôa, Silvia Fernanda de Mendonça

2018-01-01

Apresentam-se concepções de ciência identificadas em quatro instituições de Educação Não Formal, objeto de pesquisa já concluída: Museu da Vida (RJ), Espaço Ciência (PE), Museu de Ciência e Tecnologia da PUCRS (RS) e Estação Ciência (SP). Analisaram-se seus sites, com metodologia de análise de conteúdo, e suas exposições, com as seguintes categorias definidas a posteriori: Interatividade, Representação Científica e Display. Os resultados apontam tendências das concepções de ciência presentes ...

Estudos cognitivos em ciência da informaçãoCognitive studies in information science

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Gercina Ângela Borem de Oliveira Lima

2003-05-01

Full Text Available The study of the influences from Cognitive Sciences in the information Science. The Information Science has as objects of study the very basic concepts of information and knowledge. Since such concepts have an inherently trans-disciplinary character, the Information Science has been largely influenced by many disciplines, particularly the Cognitive Science. Regardless of this, it is observed that such concepts have not been properly discussed within the Information Science. To deal with this concern, it has been structured in the Escola de Ciência da Informação (ECI of the Universidade Federal de Minas Gerais (UFMG, a research group denoted “Cognitive Studies in Information Science”. This work aims to discuss the relationships between the Information Science and the Cognitive Science. In order to achieve this purpose, one formerly presents the major approaches within the Cognitive Science, contextualizing their aspects that mostly influence the Information Science, and then one discuss some perspectives for the future relationship of these two disciplines.O estudo da influência das Ciências Cognitivas na Ciência da Informação. A Ciência da Informação, que tem como objetos de estudo a informação e o conhecimento, discute-os sob vários pontos de vista, sendo um deles, o cognitivo. Observa-se que os conceitos não têm sido adequadamente discutidos à luz das Ciências Cognitivas, apesar da Ciência da Informação sofrer muitas influências daquela disciplina. Em função dessas questões, estruturou-se, na Escola de Ciência da Informação–ECI da Universidade Federal de Minas Gerais-UFMG, o Grupo de Pesquisa “Estudos Cognitivos em Ciência da Informação” – GECCI. Neste trabalho, marco inicial das discussões do grupo, tem-se o objetivo de discutir as relações da Ciência da Informação com as Ciências Cognitivas. Para melhor compreensão desse relacionamento, serão apresentadas as principais vertentes das ci

Communication: CDFT-CI couplings can be unreliable when there is fractional charge transfer

International Nuclear Information System (INIS)

Mavros, Michael G.; Van Voorhis, Troy

2015-01-01

Constrained density functional theory with configuration interaction (CDFT-CI) is a useful, low-cost tool for the computational prediction of electronic couplings between pseudo-diabatic constrained electronic states. Such couplings are of paramount importance in electron transfer theory and transition state theory, among other areas of chemistry. Unfortunately, CDFT-CI occasionally fails significantly, predicting a coupling that does not decay exponentially with distance and/or overestimating the expected coupling by an order of magnitude or more. In this communication, we show that the eigenvalues of the difference density matrix between the two constrained states can be used as an a priori metric to determine when CDFT-CI are likely to be reliable: when the eigenvalues are near 0 or ±1, transfer of a whole electron is occurring, and CDFT-CI can be trusted. We demonstrate the utility of this metric with several illustrative examples

Communication: CDFT-CI couplings can be unreliable when there is fractional charge transfer

Energy Technology Data Exchange (ETDEWEB)

Mavros, Michael G.; Van Voorhis, Troy, E-mail: tvan@mit.edu [Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, Massachusetts 02139 (United States)

2015-12-21

Constrained density functional theory with configuration interaction (CDFT-CI) is a useful, low-cost tool for the computational prediction of electronic couplings between pseudo-diabatic constrained electronic states. Such couplings are of paramount importance in electron transfer theory and transition state theory, among other areas of chemistry. Unfortunately, CDFT-CI occasionally fails significantly, predicting a coupling that does not decay exponentially with distance and/or overestimating the expected coupling by an order of magnitude or more. In this communication, we show that the eigenvalues of the difference density matrix between the two constrained states can be used as an a priori metric to determine when CDFT-CI are likely to be reliable: when the eigenvalues are near 0 or ±1, transfer of a whole electron is occurring, and CDFT-CI can be trusted. We demonstrate the utility of this metric with several illustrative examples.

Communication: CDFT-CI couplings can be unreliable when there is fractional charge transfer

Science.gov (United States)

Mavros, Michael G.; Van Voorhis, Troy

2015-12-01

Constrained density functional theory with configuration interaction (CDFT-CI) is a useful, low-cost tool for the computational prediction of electronic couplings between pseudo-diabatic constrained electronic states. Such couplings are of paramount importance in electron transfer theory and transition state theory, among other areas of chemistry. Unfortunately, CDFT-CI occasionally fails significantly, predicting a coupling that does not decay exponentially with distance and/or overestimating the expected coupling by an order of magnitude or more. In this communication, we show that the eigenvalues of the difference density matrix between the two constrained states can be used as an a priori metric to determine when CDFT-CI are likely to be reliable: when the eigenvalues are near 0 or ±1, transfer of a whole electron is occurring, and CDFT-CI can be trusted. We demonstrate the utility of this metric with several illustrative examples.

TravisTorrent : Synthesizing Travis CI and GitHub for Full-Stack Research on Continuous Integration

NARCIS (Netherlands)

Beller, M.M.; Gousios, Giorgos; Zaidman, A.E.

2017-01-01

Continuous Integration (CI) has become a best practice of modern software development. Thanks in part to its tight integration with GitHub, Travis CI has emerged as arguably the most widely used CI platform for Open-Source Software (OSS) development. However, despite its prominent role in Software

Rola aktywności ruchowej w zapobieganiu zaburzeniom poznawczym

Directory of Open Access Journals (Sweden)

Andrzej W. Ziemba

2014-11-01

Full Text Available Regularna aktywność ruchowa wywołuje szereg zmian adaptacyjnych, zwłaszcza w układzie krążenia i przemianie materii. W licznych pracach na temat pojedynczego wysiłku i wzmożonej aktywności fizycznej pojawia się coraz więcej potwierdzeń ich korzystnego wpływu na kształtowanie funkcji poznawczych. U podstaw mechanizmów związanych z tym wpływem leżą zmiany anatomiczne i funkcjonalne, m.in. zwiększenie przepływu krwi przez mózg, angiogenezy i neurogenezy, objętości istoty szarej w korze czołowej i skroniowej. Wysiłek pobudza wydzielanie czynników troficznych, wśród których dla procesów poznawczych, plastyczności synaptycznej, poprawy szlaków sygnałowych neurogenezy i funkcji naczyniowych kluczowe są czynnik troficzny pochodzenia mózgowego i insulinopodobny czynnik wzrostowy. Aktywność ruchowa wywołuje wzmożoną ekspresję czynnika troficznego pochodzenia mózgowego, co pozytywnie wpływa na procesy energetyczne i aktywuje w mózgu wiele układów energetycznych, które korzystnie modyfikują potencjał synaptyczny przetwarzania informacji ważnych w kształtowaniu funkcji poznawczych. Wysiłek redukuje stan zapalny przez obniżenie we krwi stężenia cytokin prozapalnych, mogących się przyczyniać do rozwoju procesów neurodegeneracyjnych. Redukuje czynniki ryzyka zespołu metabolicznego, a zwłaszcza nadciśnienie i insulinooporność, więc zmniejsza ryzyko wystąpienia zaburzeń czynności poznawczych, poprawia funkcjonowanie mózgu, opóźnia początek i spowalnia rozwój zaburzeń w chorobach neurodegeneracyjnych, a wśród nich w chorobie Alzheimera i chorobie Parkinsona. Za sprawą wymienionych mechanizmów aktywność ruchowa wydaje się niezbędna do zachowania prawidłowych funkcji poznawczych w każdym wieku.

Combustion Stratification for Naphtha from CI Combustion to PPC

KAUST Repository

Vallinayagam, R.

2017-03-28

This study demonstrates the combustion stratification from conventional compression ignition (CI) combustion to partially premixed combustion (PPC). Experiments are performed in an optical CI engine at a speed of 1200 rpm for diesel and naphtha (RON = 46). The motored pressure at TDC is maintained at 35 bar and fuelMEP is kept constant at 5.1 bar to account for the difference in fuel properties between naphtha and diesel. Single injection strategy is employed and the fuel is injected at a pressure of 800 bar. Photron FASTCAM SA4 that captures in-cylinder combustion at the rate of 10000 frames per second is employed. The captured high speed video is processed to study the combustion homogeneity based on an algorithm reported in previous studies. Starting from late fuel injection timings, combustion stratification is investigated by advancing the fuel injection timings. For late start of injection (SOI), a direct link between SOI and combustion phasing is noticed. At early SOI, combustion phasing depends on both intake air temperature and SOI. In order to match the combustion phasing (CA50) of diesel, the intake air temperature is increased to 90°C for naphtha. The combustion stratification from CI to PPC is also investigated for various level of dilution by displacing oxygen with nitrogen in the intake. The start of combustion (SOC) was delayed with the increase in dilution and to compensate for this, the intake air temperature is increased. The mixture homogeneity is enhanced for higher dilution due to longer ignition delay. The results show that high speed image is initially blue and then turned yellow, indicating soot formation and oxidation. The luminosity of combustion images decreases with early SOI and increased dilution. The images are processed to generate the level of stratification based on the image intensity. The level of stratification is same for diesel and naphtha at various SOI. When O concentration in the intake is decreased to 17.7% and 14

PAT: From Western solid dosage forms to Chinese materia medica preparations using NIR-CI.

Science.gov (United States)

Zhou, Luwei; Xu, Manfei; Wu, Zhisheng; Shi, Xinyuan; Qiao, Yanjiang

2016-01-01

Near-infrared chemical imaging (NIR-CI) is an emerging technology that combines traditional near-infrared spectroscopy with chemical imaging. Therefore, NIR-CI can extract spectral information from pharmaceutical products and simultaneously visualize the spatial distribution of chemical components. The rapid and non-destructive features of NIR-CI make it an attractive process analytical technology (PAT) for identifying and monitoring critical control parameters during the pharmaceutical manufacturing process. This review mainly focuses on the pharmaceutical applications of NIR-CI in each unit operation during the manufacturing processes, from the Western solid dosage forms to the Chinese materia medica preparations. Finally, future applications of chemical imaging in the pharmaceutical industry are discussed. Copyright © 2015 John Wiley & Sons, Ltd.

Binge Drinking Associations with Patrons' Risk Behaviors and Alcohol Effects after Leaving a Nightclub: Sex Differences in the "Balada com Ciência" Portal Survey Study in Brazil.

Science.gov (United States)

Sanchez, Zila M; Ribeiro, Karen J; Wagner, Gabriela A

2015-01-01

The purpose of the present study was to investigate the potential associations of binge drinking detected at the exit of nightclubs and risk behaviors and alcohol effects just after leaving the venue in a representative sample of Brazilian nightclub patrons according to sex. For this purpose, a portal survey study called Balada com Ciência was conducted in 2013 in the megacity of São Paulo, Brazil, using a two-stage cluster sampling survey design. Individual-level data were collected in 2422 subjects at the entrance and 1822 subjects at the exit of 31 nightclubs, and breath alcohol concentration (BrAC) was measured using a breathalyzer. The following day, 1222 patrons answered an online follow-up survey that included questions about risk behaviors and alcohol effects practiced just after leaving the nightclub. Weighted logistic regressions were used to analyze binge drinking associated with risk behaviors by sex. For both sexes, the most prevalent risk behaviors practiced after leaving a nightclub were drinking and driving (men=27.9%; women=20.4%), the use of illicit drugs (men=15.8%; women=9.4%) and risky sexual behavior (men=11.4%; women=6.8%). The practice of binge drinking increased the behavior of illicit drug use after leaving the nightclub by 2.54 times [95% CI: 1.26-5.09] among men who drank and increased the risk of an episode of new alcohol use by 5.80 times [95% CI: 1.50-22.44] among women who drank. Alcoholic blackouts were more prevalent among men [OR=8.92; 95% CI: 3.83-20.80] and women [OR= 5.31; 95% CI: 1.68-16.84] whose BrAC was equivalent to binge drinking compared with patrons with a lower BrAC. Public policies aiming to reduce patrons' BrAC at the exit of nightclubs, such as staff training in responsible beverage service and legislation to prevent alcohol sales to drunk individuals, would be useful to protect patrons from the risk behaviors associated with binge drinking in nightclubs.

Binge Drinking Associations with Patrons’ Risk Behaviors and Alcohol Effects after Leaving a Nightclub: Sex Differences in the "Balada com Ciência" Portal Survey Study in Brazil

Science.gov (United States)

Sanchez, Zila M.; Ribeiro, Karen J.; Wagner, Gabriela A.

2015-01-01

The purpose of the present study was to investigate the potential associations of binge drinking detected at the exit of nightclubs and risk behaviors and alcohol effects just after leaving the venue in a representative sample of Brazilian nightclub patrons according to sex. For this purpose, a portal survey study called Balada com Ciência was conducted in 2013 in the megacity of São Paulo, Brazil, using a two-stage cluster sampling survey design. Individual-level data were collected in 2422 subjects at the entrance and 1822 subjects at the exit of 31 nightclubs, and breath alcohol concentration (BrAC) was measured using a breathalyzer. The following day, 1222 patrons answered an online follow-up survey that included questions about risk behaviors and alcohol effects practiced just after leaving the nightclub. Weighted logistic regressions were used to analyze binge drinking associated with risk behaviors by sex. For both sexes, the most prevalent risk behaviors practiced after leaving a nightclub were drinking and driving (men=27.9%; women=20.4%), the use of illicit drugs (men=15.8%; women=9.4%) and risky sexual behavior (men=11.4%; women=6.8%). The practice of binge drinking increased the behavior of illicit drug use after leaving the nightclub by 2.54 times [95% CI: 1.26-5.09] among men who drank and increased the risk of an episode of new alcohol use by 5.80 times [95% CI: 1.50-22.44] among women who drank. Alcoholic blackouts were more prevalent among men [OR=8.92; 95% CI: 3.83-20.80] and women [OR= 5.31; 95% CI: 1.68-16.84] whose BrAC was equivalent to binge drinking compared with patrons with a lower BrAC. Public policies aiming to reduce patrons’ BrAC at the exit of nightclubs, such as staff training in responsible beverage service and legislation to prevent alcohol sales to drunk individuals, would be useful to protect patrons from the risk behaviors associated with binge drinking in nightclubs. PMID:26287954

Coupling between the voltage-sensing and phosphatase domains of Ci-VSP.

Science.gov (United States)

Villalba-Galea, Carlos A; Miceli, Francesco; Taglialatela, Maurizio; Bezanilla, Francisco

2009-07-01

The Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP) shares high homology with the phosphatidylinositol phosphatase enzyme known as PTEN (phosphatase and tensin homologue deleted on chromosome 10). We have taken advantage of the similarity between these proteins to inquire about the coupling between the voltage sensing and the phosphatase domains in Ci-VSP. Recently, it was shown that four basic residues (R11, K13, R14, and R15) in PTEN are critical for its binding onto the membrane, required for its catalytic activity. Ci-VSP has three of the basic residues of PTEN. Here, we show that when R253 and R254 (which are the homologues of R14 and R15 in PTEN) are mutated to alanines in Ci-VSP, phosphatase activity is disrupted, as revealed by a lack of effect on the ionic currents of KCNQ2/3, where current decrease is a measure of phosphatase activity. The enzymatic activity was not rescued by the introduction of lysines, indicating that the binding is an arginine-specific interaction between the phosphatase binding domain and the membrane, presumably through the phosphate groups of the phospholipids. We also found that the kinetics and steady-state voltage dependence of the S4 segment movement are affected when the arginines are not present, indicating that the interaction of R253 and R254 with the membrane, required for the catalytic action of the phosphatase, restricts the movement of the voltage sensor.

Oops, My Tests Broke the Build : An Explorative Analysis of Travis CI with GitHub

NARCIS (Netherlands)

Beller, M.M.; Gousios, Giorgos; Zaidman, A.E.

2017-01-01

AbContinuous Integration (CI) has become a best practice of modern software development. Yet, at present, we have a shortfall of insight into the testing practices that are common in CI-based software development. In particular, we
seek quantifiable evidence on how central testing is to the CI

Ocena Nośności Konstrukcji Nawierzchni Lotniskowych Metodą Acn-Pcn

Directory of Open Access Journals (Sweden)

Wesołowski Mariusz

2014-12-01

Full Text Available Konstrukcje nawierzchni lotniskowych są projektowane na określony okres eksploatacji przy założeniu prognozowanego natężenia i struktury ruchu lotniczego. Bezpieczeństwo wykonywania operacji lotniczych przez statki powietrzne na nawierzchniach lotniskowych zależy przede wszystkim od stanu nośności ich konstrukcji. W związku z tym, kontrolne badania nośności należy przeprowadzać okresowo, gdyż informacja o aktualnym stanie eksploatacyjnym nawierzchni lotniskowej stanowi podstawę do podejmowania decyzji o rodzajach statków powietrznych dopuszczonych do ruchu, intensywności ruchu lotniczego oraz terminach rozpoczęcia prac remontowych lub modernizacyjnych. Aktualnie do oceny nośności nawierzchni lotniskowych stosuje się metodę ACN-PCN, która została wprowadzona przez Organizację Międzynarodowego Lotnictwa Cywilnego ICAO (International Civil Aviation Organization. W artykule przedstawiony został sposób wyznaczania i opisu wskaźnika PCN

Fazer ciência: o lugar do conceito

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Wilton Garcia

2007-06-01

Full Text Available Este texto visa abrir uma discussão acerca da pesquisa contemporânea, investindo o enfoque no discurso científico para uma abordagem dinâmica de estratégias discursivas. Tento realizar uma reflexão crítica sobre a produção do saber em alguns procedimentos conceituais. Neste caso, remeto o olhar a uma consideração teórico-metodológica que pretende contribuir à atualização do discurso da ciência, hoje, e permita propor maior flexibilidade e deslocamento diante das diferentes produções de conhecimento. Este trabalho, portanto, não pretende expor, diretamente, idéias sobre ciência, mas sobre o discurso dito científico. Nesta investigação crítica, apresento sucintamente a noção de pós-(desconstrução. Utilizo os estudos contemporâneos como eixo teórico-metodológico para este desenvolvimento argumentativo. Os estudos contemporâneos pesquisam as atualizações de conceitos, que se organizam mediante a produção de atualidades e vasculham uma (redimensão teórica e política, associada ao sistema flexível da linguagem. Essas atualizações esboçam a área dos estudos contemporâneos em sua intensidade descritiva, quando aciona um olhar investigativo sobre as inovações no discurso científico, hoje.

Korzyści karmienia piersią dla matki

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Magdalena Gibas-Dorna

2012-12-01

Full Text Available Powszechnie wiadomo, że karmienie piersią pozytywnie wpływa na zdrowie dziecka oraz jego rozwój intelek‑ tualny. światowa Organizacja Zdrowia (World Health Organization, WHO zaleca rozpoczęcie karmienia piersią od pierwszej godziny po porodzie i jego kontynuację przez okres co najmniej 6 miesięcy, a w miarę urozmaicania diety dziecka rekomenduje utrzymanie tego sposobu żywienia mniej więcej do 2. roku życia, traktując mleko matki jako najlepszy jakościowo pokarm uzupełniający. Coraz częściej podkreśla się protek‑ cyjną rolę karmienia naturalnego w rozwoju różnych chorób u matek oraz potencjalne skutki unikania prze‑ dłużonej laktacji. Wydaje się, że korzyści dla matki mają charakter wczesny (podczas połogu oraz długofa‑ lowy. Tuż po porodzie karmienie piersią przyspiesza obkurczanie macicy, zapobiega nadmiernej utracie krwi, chroni przed niedokrwistością z niedoboru żelaza, przeciwdziała wystąpieniu depresji poporodowej, umacnia więź matka – dziecko oraz poprawia zaburzoną w tym okresie jakość snu. Korzyści długofalowe wiążą się z obniżeniem ryzyka wystąpienia niektórych chorób nowotworowych (rak sutka, rak endometrium, rak jajni‑ ka, chorób sercowo‑naczyniowych (choroba niedokrwienna serca, nadciśnienie tętnicze, zaburzeń metabo‑ licznych (cukrzyca, nietolerancja glukozy, otyłość, hiperlipidemia, hiperinsulinemia, reumatoidalnego zapa‑ lenia stawów czy osteoporozy. Przedłużenie okresu laktacji i karmienia piersią ma również wymierną korzyść ekonomiczną i stanowi darmową naturalną antykoncepcję. Poniższa praca podsumowuje aktualny stan wie‑ dzy na temat wpływu karmienia piersią na zdrowie matek karmiących.

Korzyści z podejmowania regularnej aktywności fizycznej przez osoby starsze = The benefits of regular physical activity for the elderly

Directory of Open Access Journals (Sweden)

U. Kaźmierczak

2015-01-01

3Wydział Kultury Fizycznej, Zdrowia i Turystyki, Uniwersytet Kazimierza Wielkiego w Bydgoszczy   Słowa kluczowe: regularna aktywność fizyczna, osoby starsze.   Keywords: regular physical activity, elderly.   Abstrakt W państwach rozwiniętych i rozwijających się coraz większą grupę społeczeństw stanowią seniorzy. Świadomość problemu spowodowała podjęcie powszechnej dyskusji ekspertów i praktyków z dziedzin medycznych na temat konieczności działań niezbędnych dla zapewnienia społeczeństwom pomyślnej starości. Od dawna wskazuje się, że brak aktywności ruchowej jest dla zdrowia niebezpieczny. Starzeniu się układu sercowo-naczyniowego towarzyszy dużo niekorzystnych zmian strukturalnych, czynnościowych i biochemicznych. Za typowe dla tego okresu zmiany uważa się osłabienie możliwości relaksacji włókien mięśniowych, co może być przyczyną rozkurczowej niewydolności serca. Trening zdrowotny – jest rodzajem aktywności fizycznej wykonywanej z powodów medycznych. Celem jest uzyskanie efektów fizycznych oraz psychicznych przeciwdziałających zmniejszaniu się zdolności adaptacyjnych organizmu. Eksperci przekonują osoby starsze o korzyściach płynących z aktywnego fizycznie stylu życia. Bogate piśmiennictwo poruszające tematykę medycznych aspektów procesu starzenia, mówi o niezaprzeczalnym znaczeniu ruchu dla toczących się w ludzkim ciele procesów inwolucyjnych. Aktywność fizyczna odpowiednio dozowana jest w stanie wyraźnie zmniejszyć negatywny wpływ tych zmian i jak najdłużej pozwolić utrzymać zdrowie fizyczne, psychiczne i społeczne. Zauważono, że systematycznie dozowany wysiłek fizyczny zmniejsza ryzyko wystąpienia wielu chorób np. cukrzycy, miażdżycy, choroby niedokrwiennej serca. Liczne badania naukowe i bogate piśmiennictwo gerontologiczne przedstawiają najnowsze doniesienia specjalistów o tym, jak należy prawidłowo przygotować i prowadzić trening fizyczny z osobami starszymi

SISTEM PENJUALAN SPARE PART TOKO AJM MOTOR MENGGUNAKAN CI BERBASIS ARSITEKTUR MVC

Directory of Open Access Journals (Sweden)

Ade Setiadi

2016-11-01

Full Text Available Saat ini penggunaan komputer dan perangkat lunak semakin banyak hingga ke berbagai kehidupan, bahkan sampai pada bidang ekonomi. Sistem Informasi merupakan peranan sangat penting dalam kegiatan bisnis di suatu perusahaan. Toko AJM Motor bergerak dalam bidang penjualan spare part mobil dan masih menggunakan cara yang konvensional dalam mengolah data tentang transaksi penjualan, untuk itu Toko AJM Motor membutuhkan sistem informasi yang dapat menunjang kelancaran dalam melakukan transaksi penjualannya. Dalam dunia teknologi khususnya pemrograman saat ini, baik itu desktop maupun web base semakin marak pengerjaannya menggunakan framework dan salah satu framework berbasis PHP yang banyak digunakan yaitu CodeIgniter (CI. Framework CI memang dikembangkan untuk memudahkan dalam developing aplikasi dengan struktur file source code-nya menggunakan pendekatan arsitektur Models-Views-Controller (MVC dan pemrograman berorientasi objek. Oleh sebab itu, kami menggunakan CI dalam developing aplikasi ini dengan metode Object Oriented Analysis and Design sebagai metode pengembangan system. Dengan dirancangnya sistem ini telah mempermudah pemilik toko dalam mengelola data pelanggan, supplier dan barang yang di beli dan di jual serta pembuatan laporan yang diperlukan untuk perhitungan penjualan dan dapat memberikan informasi yang berguna bagi pemilik toko secara up to date. Kata kunci: codeigniter (CI, models-views-controller (MVC, object oriented, penjualan.

Ocena efektywności podziału subwencji oświatowej dla gmin

Directory of Open Access Journals (Sweden)

Jan Herczyński

2016-06-01

Full Text Available Celem przedstawionych analiz jest ocena dopasowania podziału pomiędzy gminy części oświatowej subwencji ogólnej do kosztów dostarczania usług edukacyjnych. W artykule zarysowano problematykę związaną z podziałem subwencji oświatowej pomiędzy gminy, opisano wagi stosowane w algorytmie podziału subwencji oświatowej, skoncentrowano się na zmianach wprowadzonych do algorytmu w 2015 r. i omówiono konsekwencje wynikające ze stosowania wag wiejskich, które mają stosunkowo duży wpływ na podział środków. W ostatniej części wprowadzono miarę nieefektywności algorytmu podziału części oświatowej subwencji ogólnej i zastosowano ją do oceny podziału środków subwencyjnych pomiędzy gminy. Miara ta pozwala m.in. ilościowo ocenić efekt zmian wprowadzonych do algorytmu w 2015 r. Zaproponowano możliwe korekty wag algorytmu pozwalające na redukcję nieefektywności i zjawiska tzw. przewrotnej motywacji organów prowadzących szkoły. W podsumowaniu przedstawiono główne wnioski wynikające z analiz.

Women in the United States Marine Corps CI/HUMINT Community

National Research Council Canada - National Science Library

Reese, Jackson L

2008-01-01

The purpose of the researchers Masters of Military Arts and Science thesis is to explore the possibility of including women in the Marine Corps CI/HUMINT community without diminishing the overall unit...

Projeto Caminhão da Ciência: Popularização da Ciência no Oeste da Bahia

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E. C. V. de Magalhães

2014-11-01

Full Text Available O Projeto Caminhão da Ciência tem por objetivo promover a divulgação científica em Escolas e espaços públicos da Região Oeste da Bahia. O projeto teve início no ano de 2009, com apoio do CNPq, ocorrendo a sua primeira apresentação no ano de 2010, na feira libre de Barreiras. Várias áreas do conhecimento são contempladas entre eles: Biologia, Física, Química, Matemática, Geologia e Engenharias. O projeto se fundamenta por apresentações de temáticas desenvolvidas por alunos de graduação, sob a orientação de professores da Universidade Federal do Oeste da Bahia-UFOB, envolvidos no projeto. Diversas temáticas são desenvolvidas na forma trabalhos interdisciplinares entre eles: elaboração de maquetes, experimentos com uso de materiais alternativos, vídeos, jogos e ainda informativos em websites e webblogs. Para as apresentações do projeto, são realizadas visitas nas escolas ou outros espaçoes e os materiais trasportados no Caminhão são montados no espaço físico disponibilizado, criando um cenário similar ao de uma feira de ciências. Neste trabalho são apresentados relatos de apresentações realizadas em Escolas, enfatizando os resultados obtidos que demonstram a socialização do conhecimento científico entre os monitores e a comunidade assistida, além da interação entre a Universidade e a sociedade.

Tanzania national survey on iodine deficiency: impact after twelve years of salt iodation

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Kimboka Sabas

2009-09-01

Full Text Available Abstract Background In many low-income countries, children are at high risk of iodine deficiency disorders, including brain damage. In the early 1990s, Tanzania, a country that previously suffered from moderate to severe iodine deficiency, adopted universal salt iodation (USI as an intervention strategy, but its impact remained unknown. Methods We report on the first national survey in mainland Tanzania, conducted in 2004 to assess the extent to which iodated salt was used and its apparent impact on the total goitre prevalence (TGP and urinary iodine concentrations (UIC among the schoolchildren after USI was initiated. In 2004, a cross-sectional goitre survey was conducted; covering 140,758 schoolchildren aged 6 - 18 years were graded for goitre according to new WHO goitre classification system. Comparisons were made with district surveys conducted throughout most of the country during the 1980s and 90s. 131,941 salt samples from households were tested for iodine using rapid field test kits. UIC was determined spectrophotometrically using the ammonium persulfate digestion method in 4523 sub-sampled children. Results 83.6% (95% CI: 83.4 - 83.8 of salt samples tested positive for iodine. Whereas the TGP was about 25% on average in the earlier surveys, it was 6.9% (95%CI: 6.8-7.0 in 2004. The TGP for the younger children, 6-9 years old, was 4.2% (95%CI: 4.0-4.4, n = 41,965. In the 27 goitre-endemic districts, TGP decreased from 61% (1980s to 12.3% (2004. The median UIC was 204 (95% CF: 192-215 μg/L. Only 25% of children had UIC Conclusion Our study demonstrates a marked improvement in iodine nutrition in Tanzania, twelve years after the initiation of salt iodation programme. The challenge in sustaining IDD elimination in Tanzania is now two-fold: to better reach the areas with low coverage of iodated salt, and to reduce iodine intake in areas where it is excessive. Particular attention is needed in improving quality control at production level and

AHRQ series on complex intervention systematic reviews-paper 7: PRISMA-CI elaboration and explanation.

Science.gov (United States)

Guise, Jeanne-Marie; Butler, Mary; Chang, Christine; Viswanathan, Meera; Pigott, Terri; Tugwell, Peter

2017-10-01

Complex interventions are widely used in health care, public health, education, criminology, social work, business, and welfare. They have increasingly become the subject of systematic reviews and are challenging to effectively report. The Complex Interventions Methods Workgroup developed an extension to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Complex Interventions (PRISMA-CI). Following the EQUATOR Network guidance for Preferred Reporting Items for Systematic Reviews and Meta-Analysis extensions, this Explanation and Elaboration (EE) document accompanies the PRISMA-CI checklist to promote consistency in reporting of systematic reviews of complex interventions. The EE document explains the meaning and rationale for each unique PRISMA-CI checklist item and provides examples to assist systematic review authors in operationalizing PRISMA-CI guidance. The Complex Interventions Workgroup developed PRISMA-CI as an important start toward increased consistency in reporting of systematic reviews of complex interventions. Because the field is rapidly expanding, the Complex Interventions Methods Workgroup plans to re-evaluate periodically for the need to add increasing specificity and examples as the field matures. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Analyzing nitrogen concentration using carrier illumination (CI) technology for DPN ultra-thin gate oxide

International Nuclear Information System (INIS)

Li, W.S.; Wu, Bill; Fan, Aki; Kuo, C.W.; Segovia, M.; Kek, H.A.

2005-01-01

Nitrogen concentration in the gate oxide plays a key role for 90 nm and below ULSI technology. Techniques like secondary ionization mass spectroscopy (SIMS) and X-ray photoelectron spectroscopy (XPS) are commonly used for understanding N concentration. This paper describes the application of the carrier illuminationTM (CI) technique to measure the nitrogen concentration in ultra-thin gate oxides. A set of ultra-thin gate oxide wafers with different DPN (decoupled plasma nitridation) treatment conditions were measured using the CI technique. The CI signal has excellent correlation with the N concentration as measured by XPS

Ética, ciência e tecnologia

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Ivan Domingues

2004-06-01

Full Text Available O artigo visa pensar a relação entre ética, ciência e tecnologia, enfatizando o problema de sua revinculação depois da cisão entre os juízos de fato e os juízos de valor, ocorrida no início dos tempos modernos. Uma vez examinada a ética da aristocracia guerreira e a moral do santo, procura-se delinear o caminho tomando como referência a ética da responsabilidade, cujo protótipo é a moral do sábio, desaparecido no curso dos tempos modernos, em razão da fragmentação do saber e do advento do especialista. Ao fim do estudo, é discutida a relação entre a ética e a metafísica, com o intuito de ajustar a questão antropológica à perspectiva cosmológica, bem como de fornecer as bases de um novo humanismo, objetivando a humanização da técnica e a geração de um novo homem, alfabetizado em ciência, tecnologia e humanidades.The article aims at thinking the relation among ethics, science and technology, emphasizing the problem of their re-tying, after the division into judgments of fact and judgments of value, wich happened in the begininning of modern times. Since the warlike aristocracy's ethics and the saint man's moral are examined, it tries to outline its way, taking as a reference the ethics of responsability, whose prototype is the wise man's moral, which disappeared in the course of modern times, due to the fragmentation of knowing and the advent of the specialist. At the end of the study, the relationship between ethics and metaphysics is discussed, aiming at adjusting the anthropological question to the cosmological perspective, as well as at providing the bases of a new humanism, objectifying the humanization of the technique and the generation of a new man, literate at science, technology and the humanities.

Ciência da Computação

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André Felipe Henriques Librantz

2006-01-01

Full Text Available Este trabalho apresenta um sistema de navegação autônoma de robôs construídos com kits Lego Mindstorms, para cálculo de trajetórias. Esse sistema pode ser utilizado como instrumento pedagógico multidisciplinar no curso de Ciência da Computação, uma vez que, para o seu desenvolvimento são necessários conhecimentos de algoritmos, linguagem de programação, lógica computacional, estrutura de dados, inteligência artificial (IA, redes de computadores, computação gráfica e robótica.

O Museu de Ciência: espaço da história da ciência The Science Museum: a place of history of science

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Maria Esther Alvarez Valente

2005-04-01

Full Text Available O artigo apresenta uma reflexão sobre o Museu de Ciência a partir de sua dimensão educativa. O que está em discussão é a abordagem sobre os temas científicos e a exploração dos objetos museológicos apresentados no sentido de facilitar o entendimento público da Ciência. Principalmente a partir da segunda metada do século XX, a comunicação nestes espaços, voltada para o público leigo, opta por estratégias que priorizam, quase exclusivamente, a apresentação de fenômenos científicos, construindo desta maneira saberes a-históricos. Com base na perspectiva da História da Ciência o esforço, hoje, é o de ampliar a interpretação dos temas e objetos, revelando a intangibilidade ligada a eles, e que compreendem o ato de criação científico, os processos de conhecimento da ciência e sua relação com o homem e a sociedade. Trata-se de uma abordagem que auxilia os indivíduos a dar significado aos conteúdos científicos.The article is bringsa reflection on the science museum focusinged on its educational dimension. The discussion is about the approach of the interpretation ofn scientific themes and objects, both presented in the museum's exhibitions, in order to promote the public's understanding of science. Starting mainly in the second half of the twentieth century, communication occurred in Science Museums and more precisely in Science Centres, with presentations focused, exclusively on the scientific phenomena. What results is a knowledge without historical foundations. Instead we propose another approach based on the history of science perspective. It opens up the interpretation ofn the intangible aspectsside of the objects as well asand the cold information. It emphasisesis the act of scientificce creation, the process of science knowledge and its relationship with man and society. The new approach will help people give significance to the scientific contents.

Performance and emission of CI engine fuelled with camelina sativa oil

International Nuclear Information System (INIS)

Kruczyński, Stanisław W.

2013-01-01

Highlights: ► Camelina sativa as a potential source of alternative fuel. ► Neat camelina sativa oil as a fuel for CI engine. ► The engine performance and emissions of CI engine fuelled with neat camelina sativa oil. ► Comparison of rate of heat release for camelina sativa oil and diesel oil. - Abstract: The paper describes the results of the tests of CI Perkins 1104C-44 engine fuelled with camelina sativa oil. The engine was not especially calibrated for fuelling with the vegetable fuel. During the test the engine performance and emissions were analysed. For comparison the same speed characteristic was examined for standard fuelling of the engine with diesel oil. In order to understand the engine performance and emission the mass fraction burnt and the rate of heat release was calculated and compared for the same energy provided to the engine cylinder with the injected fuels. The results show that there is possible to receive relatively good engine performance for fuelling the engine with camelina sativa oil but there is a need to change the calibration parameters of the engine fuel system when the engine is fuelled with this fuel.

Dietary salt reduction and cardiovascular disease rates in India: a mathematical model.

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Sanjay Basu

Full Text Available Reducing salt intake has been proposed to prevent cardiovascular disease in India. We sought to determine whether salt reductions would be beneficial or feasible, given the worry that unrealistically large reductions would be required, worsening iodine deficiency and benefiting only urban subpopulations.Future myocardial infarctions (MI and strokes in India were predicted with a Markov model simulating men and women aged 40 to 69 in both urban and rural locations, incorporating the risk reduction from lower salt intake. If salt intake does not change, we expect ~8.3 million MIs (95% CI: 6.9-9.6 million, 830,000 strokes (690,000-960,000 and 2.0 million associated deaths (1.5-2.4 million per year among Indian adults aged 40 to 69 over the next three decades. Reducing intake by 3 g/day over 30 years (-0.1 g/year, 25% reduction would reduce annual MIs by 350,000 (a 4.6% reduction; 95% CI: 320,000-380,000, strokes by 48,000 (-6.5%; 13,000-83,000 and deaths by 81,000 (-4.9%; 59,000-100,000 among this group. The largest decline in MIs would be among younger urban men, but the greatest number of averted strokes would be among rural men, and nearly one-third of averted strokes and one-fifth of averted MIs would be among rural women. Only under a highly pessimistic scenario would iodine deficiency increase (by <0.0001%, ~1600 persons, since inadequate iodized salt access--not low intake of iodized salt--is the major cause of deficiency and would be unaffected by dietary salt reduction.Modest reductions in salt intake could substantially reduce cardiovascular disease throughout India.

The radiation shielding potential of CI and CM chondrites

Science.gov (United States)

Pohl, Leos; Britt, Daniel T.

2017-03-01

Galactic Cosmic Rays (GCRs) and Solar Energetic Particles (SEPs) pose a serious limit on the duration of deep space human missions. A shield composed of a bulk mass of material in which the incident particles deposit their energy is the simplest way to attenuate the radiation. The cost of bringing the sufficient mass from the Earth's surface is prohibitive. The shielding properties of asteroidal material, which is readily available in space, are investigated. Solution of Bethe's equation is implemented for incident protons and the application in composite materials and the significance of various correction terms are discussed; the density correction is implemented. The solution is benchmarked and shows good agreement with the results in literature which implement more correction terms within the energy ranges considered. The shielding properties of CI and CM asteroidal taxonomy groups and major asteroidal minerals are presented in terms of stopping force. The results show that CI and CM chondrites have better stopping properties than Aluminium. Beneficiation is discussed and is shown to have a significant effect on the stopping power.

Estimating population salt intake in India using spot urine samples.

Science.gov (United States)

Petersen, Kristina S; Johnson, Claire; Mohan, Sailesh; Rogers, Kris; Shivashankar, Roopa; Thout, Sudhir Raj; Gupta, Priti; He, Feng J; MacGregor, Graham A; Webster, Jacqui; Santos, Joseph Alvin; Krishnan, Anand; Maulik, Pallab K; Reddy, K Srinath; Gupta, Ruby; Prabhakaran, Dorairaj; Neal, Bruce

2017-11-01

To compare estimates of mean population salt intake in North and South India derived from spot urine samples versus 24-h urine collections. In a cross-sectional survey, participants were sampled from slum, urban and rural communities in North and in South India. Participants provided 24-h urine collections, and random morning spot urine samples. Salt intake was estimated from the spot urine samples using a series of established estimating equations. Salt intake data from the 24-h urine collections and spot urine equations were weighted to provide estimates of salt intake for Delhi and Haryana, and Andhra Pradesh. A total of 957 individuals provided a complete 24-h urine collection and a spot urine sample. Weighted mean salt intake based on the 24-h urine collection, was 8.59 (95% confidence interval 7.73-9.45) and 9.46 g/day (8.95-9.96) in Delhi and Haryana, and Andhra Pradesh, respectively. Corresponding estimates based on the Tanaka equation [9.04 (8.63-9.45) and 9.79 g/day (9.62-9.96) for Delhi and Haryana, and Andhra Pradesh, respectively], the Mage equation [8.80 (7.67-9.94) and 10.19 g/day (95% CI 9.59-10.79)], the INTERSALT equation [7.99 (7.61-8.37) and 8.64 g/day (8.04-9.23)] and the INTERSALT equation with potassium [8.13 (7.74-8.52) and 8.81 g/day (8.16-9.46)] were all within 1 g/day of the estimate based upon 24-h collections. For the Toft equation, estimates were 1-2 g/day higher [9.94 (9.24-10.64) and 10.69 g/day (9.44-11.93)] and for the Kawasaki equation they were 3-4 g/day higher [12.14 (11.30-12.97) and 13.64 g/day (13.15-14.12)]. In urban and rural areas in North and South India, most spot urine-based equations provided reasonable estimates of mean population salt intake. Equations that did not provide good estimates may have failed because specimen collection was not aligned with the original method.

Deskrypcja długości i szerokości stóp kobiet i mężczyzn w obciążeniu masą własną, w wieku od 4 do 18 lat w świetle mory projekcyjnej

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Mirosław Mrozkowiak

2015-09-01

Mirosław Mrozkowiak   Uniwersytet Kazimierza Wielkiego, Instytut Kultury Fizycznej, Bydgoszcz e-mail: magmar54@interia.pl, strona: http://wadypostawy.republika.pl   Słowa kluczowe: długość i szerokość stopy.   Streszczenie   Wstęp. Długość i szerokość stopy to cechy, których przyśpieszony wzrost w okresie pokwitania pojawia się najwcześniej. U chłopców przypada na okres między 12,5 a13 r.ż., wg innych doniesień długość i szerokość stopy u chłopców wzrasta do 18 r.ż. Z wiekiem stopa zmienia się z szerokiej i krótkiej u noworodków, do pośredniej u dzieci starszych. Cel. Określenie przebiegu zmian średnich wartości długości i szerokości stóp, okresów gwałtownego wzrostu i spowolnienia przyrostu badanych parametrów w grupie dziewcząt i chłopców w wieku od 4 do 18 lat. Materiał i metodyka. Pomiarami długości i szerokości stóp objęto populację 9804 dziewcząt i 8699 chłopców w wieku od 4 do 18 lat, z losowo wybranych przedszkoli i szkół regionu warmińsko–mazurskiego. Do oceny wykorzystano stanowisko do komputerowej oceny postawy ciała, techniką mory projekcyjnej. Wyniki. Krzywa średnich wartości długości stóp obojga płci ma bardzo zbliżony przebieg  do wykresu właściwej płci. Krzywa rozpoczyna się wartością P: 168,2, L:168,22 mm, kończy P: 238,0, L:233,3 mm. W 14 r.ż. występuje obniżenie wartości do P: 214,68, L:209,91 mm. Szerokość posiada wartość początkową P: 62,99, L:64,92 mm, końcową P: 90,8, L:90,18 mm. W 14 r.ż. występuje załamanie do wartości P: 81,82, L:82,39 mm. Wnioski     1. Przyrost długości i szerokości stóp populacji żeńskiej i męskiej od 4 do 18 r.ż. jest równomiernie intensywny, przy czym w 14 r.ż. następuje spowolnienie przyrostu wielkości badanych cech.     2. Przebieg zmian średnich wielkości długości i szerokości stopy w wieku od 4 do 18 lat regionu warmińsko – mazurskiego nie znajduje w pełni potwierdzenia w badaniach metod

Seria a Metafísica Essencial à Ciência e ao Senso Comum?

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Rafael Sandoval

2017-02-01

Full Text Available Uma das declarações mais consensuais da História da Filosofia é a que diz que a Metafísica não é ciência, mas pensamento. Neste artigo, procurar-se-á defender a tese que a Metafísica é condição para o senso comum e a ciência. Primeiro, é mostrado que os termos ao qual nós utilizamos diariamente refletem nossa imagem de mundo. Quando pensamos e fazemos previsões, fazemos o uso espontâneo de termos com significado universal. Depois, é procurado evidenciar que a ciência naturalmente faz uso de termos com significado universal quando faz previsões. Finalmente, buscará apresentar que a Metafísica é anterior às nossas hipóteses e especulações.

Hydrometallurgical treatment of plutonium. Bearing salt baths waste

International Nuclear Information System (INIS)

Bros, P.; Gozlan, J.P.; Lecomte, M.; Bourges, J.

1993-01-01

The salt flux issuing from the electrorefining of plutonium metal alloy in salt baths (KCI + NaCI) poses a difficult problem of the back-end alpha waste management. An alternative to the salt process promoted by Los Alamos Laboratory is to develop a hydrometallurgical treatment. A new process based on the electrochemistry technique in aqueous solution has been defined and tested successfully in the CEA. The diagram of the process exhibits two principal steps: in the head-end, a dissolution in HNO 3 medium accompanied with an electrolytic dechlorination leading to a quantitative elimination of chloride as CI 2 gas followed by its trapping one soda lime cartridge, a complete oxidative dissolution of the refractory Pu residues by electrogenerated Ag(II), in the back-end: the Pu and Am recoveries by chromatographic extractions. (authors). 10 figs., 9 refs

Dzieło sztuki na granicy przeszłości i przyszłości. Historia i patriotyzm w sztuce nieprofesjonalnej

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Aleksandra Weronika Jarysz

2016-01-01

Full Text Available A work of art – a link between the present and the past. History and patriotism in non-professional art In her article, the author discusses art of non-professional artists who shape the national identity in an original way. In the former professional art, the works which illustrated and uplifted history were very popular. This phenomenon is still present among folk, naive, intuitive artists, generally speaking – non-professionals. The work of their hands and imagination is a tool serving the purpose of national values and ideas, and is sometimes the basis for broader considerations on the human condition. They balance between historical facts and ahistorical generalities. The martyrdom of the Polish nation with emphasis on the events of WWII has been inspiring artists, stimulating their imagination and artistic creation. Therefore numerous ‘monuments of patriotic art’ can be found in the wood sculpture, ceramics, painting, and glass painting works from the art collection of the Toruń Maria Znamierowska-Prüfferowa Ethnographic Museum.   Dzieło sztuki na granicy przeszłości i przyszłości. Historia i patriotyzm w sztuce nieprofesjonalnej W swoim artykule autorka prezentuje sztukę twórców nieprofesjonalnych, którzy w sposób oryginalny kształtują tożsamość narodową. W dawnej sztuce profesjonalnej dzieła, które ilustrowały i uwznioślały historię były bardzo popularne. To zjawisko jest nadal aktualne wśród twórców ludowych, naiwnych, intuicyjnych, ogólnie nazywając – nieprofesjonalnych. Dzieło ich rąk i wyobraźni jest narzędziem w służbie wartości i idei narodowych, a niekiedy stanowi podstawę do szerszych rozważań nad kondycją człowieka. Balansują oni między konkretem historycznym a ahistoryczną ogólnością. Martyrologia narodu polskiego z naciskiem na wydarzenia II wojny światowej inspirowała i inspiruje twórców, pobudza ich wyobraźnię i zmusza do twórczej kreacji. Stąd też zar

Prognozowanie i ujmowanie przychodóww przedsiębiorstwie postawionymw stan upadłości likwidacyjnej

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Janusz Czerny

2010-03-01

Full Text Available W upadłości likwidacyjnej przedsiębiorstw mamy do czynienia z dwoma stru-mieniami przychodów, a mianowicie z przychodami dotyczącymi zbycia przedsię-biorstwa lub jego składników majątku oraz z przychodami związanymi z ewentual-nym kontynuowaniem działalności: Przychody ze sprzedaży przedsiębiorstwa powinny być prognozowane głównie na podstawie informacji płynących z systemu rachunkowości, co stanowi tzw. sta-tyczny aspekt upadłości, natomiast jej aspekt dynamiczny jest związany z zakre-sem i czasem kontynuowanej działalności, o czym decyduje syndyk, mając na uwa-dze naczelny cel upadłości, jakim jest optymalne zaspokojenie roszczeń wierzycieli.

As diferentes faces da razão (II. Risco, ciência e peritos

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C. M. Novais Madureira

2012-10-01

Full Text Available Em texto anterior argumentou-se contra os excessos do cientismo com que, na linha de Sokal e Bricmont, António Manuel Baptista ataca as análises sociológicas dos processos e produtos da ciência, nomeadamente as posições de Boaventura de Sousa Santos. Neste outro texto, pretende-se contestar AMB e os sokalistas no seu próprio campo, o da ciência pura e dura, mostrando que eles próprios não compreendem o estatuto das suas ciências, e tentando ponderar afirmações menos precisas, frequentes na análise da sociogénese da ciência. Trazendo a discussão para o nosso tempo, abordaremos também uma problemática não tratada no texto anterior, a do estatuto dos cientistas e tecnólogos enquanto peritos nas instâncias de decisão. Por último, tratará de analisar-se como as controvérsias entre peritos, hoje tão frequentes, são vividas no seio da comunidade científica e qual a evolução que geram na própria prática pericial.

Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033

International Nuclear Information System (INIS)

Dorow, Donna S.; Cullinane, Carleen; Conus, Nelly; Roselt, Peter; Binns, David; McCarthy, Timothy J.; McArthur, Grant A.; Hicks, Rodney J.

2006-01-01

This study was designed as ''proof of concept'' for a drug development model utilising multi-tracer serial small animal PET imaging to characterise tumour responses to molecularly targeted therapy. Mice bearing subcutaneous A431 human squamous carcinoma xenografts (n=6-8) were treated with the pan-Erb-B inhibitor CI-1033 or vehicle and imaged serially (days 0, 3 and 6 or 7) with [ 18 F]fluorodeoxyglucose, [ 18 F]fluoro-L-thymidine, [ 18 F]fluoro-azoazomycinarabinoside or [ 18 F]fluoromisonidazole. Separate cohorts (n=3) were treated identically and tumours were assessed ex vivo for markers of glucose metabolism, proliferation and hypoxia. During the study period, mean uptake of all PET tracers generally increased for control tumours compared to baseline. In contrast, tracer uptake into CI-1033-treated tumours decreased by 20-60% during treatment. Expression of the glucose transporter Glut-1 and cell cycle markers was unchanged or increased in control tumours and generally decreased with CI-1033 treatment, compared to baseline. Thymidine kinase activity was reduced in all tumours compared to baseline at day 3 but was sevenfold higher in control versus CI-1033-treated tumours by day 6 of treatment. Uptake of the hypoxia marker pimonidazole was stable in control tumours but was severely reduced following 7 days of CI-1033 treatment. CI-1033 treatment significantly affects tumour metabolism, proliferation and hypoxia as determined by PET. The PET findings correlated well with ex vivo biomarkers for each of the cellular processes studied. These results confirm the utility of small animal PET for evaluation of the effectiveness of molecularly targeted therapies and simultaneously definition of specific cellular processes involved in the therapeutic response. (orig.)

Filosofia da ciência como ferramenta microeconômica

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Fabio Barbieri

2009-06-01

Full Text Available A teoria neoclássica pressupõe conhecimento perfeito. A crítica hayekiana a essa teoria, por sua vez, afirma que esse conhecimento é resultado do processo competitivo e, portanto, não pode ser considerado como dado. O “Problema de Hayek” investiga sob que condições o conhecimento do agente se aproxima dos reais fundamentos de uma economia. A fim de solucionar o “Problema de Hayek”, o nosso artigo utiliza algumas idéias da literatura de metodologia da Ciência, conhecida como teoria do “crescimento do conhecimento” (Popper, Kuhn, Lakatos e outros. Essas idéias são utilizadas para se compreender como evolui o conhecimento dos agentes econômicos, em especial o dos empresários. Estes são vistos como ativos formuladores de teorias empresariais conjecturais criticadas no processo competitivo, não como agentes passivos que maximizam funções já conhecidas da teoria convencional. Utiliza-se a Filosofia da Ciência não para analisar metodologicamente a microeconomia, mas, sim, como ferramenta analítica pertencente à própria teoria econômica.

Diversidade sexual e ensino de ciências: buscando sentidos

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Leandro Jorge Coelho

2015-12-01

Full Text Available ResumoO objetivo desse estudo foi analisar os sentidos atribuídos por professores de Ciências e alunos à diversidade sexual. Foram utilizados: questionário, entrevista, produção de textos, análise documental e a técnica de grupo focal para a coleta de dados. De modo geral, os alunos possuem sentidos que reconhecem Lésbicas, Gays, Bissexuais e Transgêneros (LGBT como "estranhos", mesmo assim, acreditam que têm o dever de respeitar as escolhas de cada um. As travestis foram declaradamente apresentadas com repúdio por eles, sendo a homossexualidade e bissexualidade aparentemente mais aceitas. Os professores parecem manter aulas que não abordam estas questões, mesmo o Ensino de Ciências, sendo um momento privilegiado para problematizações sobre diversidade sexual e gênero. É necessário investir em discussões sobre esses temas na formação inicial e continuada de professores, buscando a construção de novos sentidos e práticas que se preocupem com o desvelamento de significados preconceituosos sobre gênero e diversidade sexual.

Do estilo em ciência e em história das ciências

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Michel Paty

2012-08-01

Full Text Available Ao considerar o conhecimento científico como uma forma de pensamento simbólico, entende-se com isso não simples sistemas de signos, mas conteúdos de pensamento (expressos por conceitos ligados entre si e que fazem sentido, que são, no espaço das representações mentais, os substitutos do "dado objetivo" que se supõe subjazer à experiência que fazemos do "mundo" pelos sentidos e, nesse nível indissociavelmente, pelo entendimento. Esse pensamento simbólico adquire densidade e consistência pela "tecelagem" realizada graças ao trabalho dos pensamentos individuais que se comunicam, social e culturalmente, inscritos no tempo da história. Da tensão dinâmica entre o sujeito do conhecimento, que busca a inteligibilidade (pela operação de sua razão, e a objetividade dos conteúdos que ele se propõe (inicialmente dados, depois modificados ou produzidos, resulta o movimento do pensamento científico e a transformação dos conhecimentos. Esse trabalho do pensamento simbólico é marcado por um estilo próprio a cada um, mas que em parte pode ser comum em contextos, escolas ou tradições. Em ciência e em história das ciências, o estilo intervém em dois níveis: o da abordagem "objetal" da produção das obras pelos cientistas e o da abordagem "reflexiva" da história epistemológica e da filosofia, que se interrogam sobre a significação tanto dos próprios conteúdos de conhecimento quanto do pensamento racional, simbólico, cuja função é manifestá-los.By considering scientific knowledge as a form of symbolic thought, we do not mean by the latter simply systems of signs, but thought contents (expressed by concepts related between them and providing meaning ; they are, in the space of mental representations, the substitutes of the «objectively given» that one supposes to underly the experience of the «world» done through the senses and the understanding, both being indissociable at this level. This symbolic thought gets

Perfluoroalkyl Substances, Sex Hormones, and Insulin-like Growth Factor-1 at 6-9 Years of Age: A Cross-Sectional Analysis within the C8 Health Project.

Science.gov (United States)

Lopez-Espinosa, Maria-Jose; Mondal, Debapriya; Armstrong, Ben G; Eskenazi, Brenda; Fletcher, Tony

2016-08-01

Exposure to some perfluoroalkyl substances (PFAS), such as perfluorohexane sulfonate (PFHxS), perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid (PFNA), may alter levels of sex hormones and insulin-like growth factor-1 (IGF-1) in animals. Human studies on this topic are scarce, and none have been conducted in young children. We investigated the relationship between levels of PFAS and estradiol, total testosterone, and IGF-1 in 2,292 children (6-9 years of age) from the C8 Health Project who lived near a chemical plant in the Mid-Ohio Valley (USA) with local contamination from PFOA. Serum samples were collected in 2005-2006 and analyzed for PFAS, sex hormones, and IGF-1. Results from regression models were expressed as the adjusted percentage difference (95% CI) per sex-specific interquartile range (IQR) increment of each PFAS serum concentration. Analyses by PFAS quartiles were also conducted. Median concentrations of PFHxS, PFOA, PFOS, and PFNA were 8, 35, 22, and 1.7 ng/mL in boys and 7, 30, 21, and 1.7 ng/mL in girls. In boys, PFOA concentrations were significantly associated with testosterone levels (-4.9%; 95% CI: -8.7, -0.8%); PFOS with estradiol (-4.0%; 95% CI: -7.7, -0.1%), testosterone (-5.8%; 95% CI: -9.4, -2.0%), and IGF-1 (-5.9%; 95% CI: -8.3, -3.3%); and PFNA with IGF-1 (-3.5%; 95% CI: -6.0, -1.0%). In girls, significant associations were found between PFOS and testosterone (-6.6%; 95% CI: -10.1, -2.8%) and IGF-1 (-5.6%; -8.2, -2.9%); and PFNA and IGF-1 (-3.8%; 95% CI: -6.4, -1.2%). In both sexes, the magnitudes of the associations decreased monotonically across quartiles for both testosterone and IGF-1 in relation to PFOS, and for IGF-1 and PFNA in girls. To our knowledge, this is the first study suggesting that PFAS are associated with lower levels of IGF-1 and sex hormones in young children. Lopez-Espinosa MJ, Mondal D, Armstrong BG, Eskenazi B, Fletcher T. 2016. Perfluoroalkyl substances, sex hormones, and

A inclusão na perspectiva do novo paradigma da ciência

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Reinoldo Marqueza

2011-12-01

Full Text Available O estudo aborda o processo de transição paradigmática da ciência moderna para a ciência pós-moderna. Salienta as características do paradigma atual, a crise desse paradigma e aponta os contornos do paradigma emergente na perspectiva do sociólogo Boaventura Sousa Santos. Refere a Educação Inclusiva como um novo processo de produção e de apropriação do conhecimento e como uma nova forma de estar na relação.Palavras-chave: Paradigma. Conhecimento. Educação Inclusiva.

O ensino de conteúdos de História e Filosofia da Ciência

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Fernando Bastos

1998-01-01

Full Text Available O presente trabalho de pesquisa consistiu em duas etapas: (i produção de um Guia de Estudos em que a história das pesquisas sobre a febre amarela (1881-1903 foi usada como subsídio para a discussão de alguns importantes aspectos do processo de produção de conhecimentos na ciência; (ii realização de experiência pedagógica em que o Guia de Estudos foi aplicado junto a alunos do ensino médio. Os resultados obtidos forneceram evidência da viabilidade do uso da História da Ciência no Ensino de Ciências.

Estudos de Comunidade e ciências sociais no Brasil

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Nemuel da Silva Oliveira

2011-12-01

Full Text Available O objetivo deste artigo é fazer um balanço da literatura sobre os Estudos de Comunidade (EC no Brasil, destacando o contexto intelectual em que foram produzidos e os debates que suscitaram, especialmente entre as décadas de 1940 e 1960. Método de pesquisa em comunidades, oriundo da Antropologia, em investigações sobre o processo de mudança social, os EC estiveram em voga nos Estados Unidos entre os anos 1920 e 1950, tendo papel fundamental na institucionalização das Ciências Sociais no Brasil. Destacamos três aspectos na produção desses estudos no país, iniciando com uma abordagem conceitual: definições, origem e sua relação com temáticas marcantes nos anos 1950. Em seguida, privilegiamos os aspectos relacionados ao papel dos EC na história das Ciências Sociais no Brasil, com destaque para o processo de institucionalização das Ciências Sociais. Por fim, revisitamos os debates que tais estudos geraram entre os cientistas sociais quanto ao padrão de trabalho sociológico a ser desenvolvido naquele momento.The purpose of this article is to examine the literature about Community Studies(CS in Brazil, highlighting their intellectual context of production and the debates evoked by them, especially between the 1940's and 1960's. As a research method arising from Anthropology on communities in social change process, CS was used in United States between 1920's and 1950's, and played a fundamental role in the institutionalization of Social Sciences in Brazil. Three aspects are highlighted on CS production: first, in a conceptual approach, we discuss their definitions, origins and relation to main topics in the 1950's. The second aspect is related to the role of CS in the history of Social Sciences, especially their institutionalization process. By the end, we revisit the debates between social scientists about the sociological work standard to be developed at that time.

Experimental and Numerical Investigation of Ethanol/Diethyl Ether Mixtures in a CI Engine

KAUST Repository

Sivasankaralingam, Vedharaj

2016-10-17

The auto-ignition characteristics of diethyl ether (DEE)/ethanol mixtures are investigated in compression ignition (CI) engines both numerically and experimentally. While DEE has a higher derived cetane number (DCN) of 139, ethanol exhibits poor ignition characteristics with a DCN of 8. DEE was used as an ignition promoter for the operation of ethanol in a CI engine. Mixtures of DEE and ethanol (DE), i.e., DE75 (75% DEE + 25% ethanol), DE50 (50% DEE + 50% ethanol) and DE25 (25% DEE + 75% ethanol), were tested in a CI engine. While DE75 and DE50 auto-ignited at an inlet air pressure of 1.5 bar, DE25 failed to auto-ignite even at boosted pressure of 2 bar. The peak in-cylinder pressure for diesel and DE75 were comparable, while DE50 showed reduced peak in-cylinder pressure with delayed start of combustion (SOC). Numerical simulations were conducted to study the engine combustion characteristics of DE mixture. A comprehensive detailed chemical kinetic model was created to represent the combustion of DE mixtures. The detailed mechanism was then reduced using standard direct relation graph (DRG-X) method and coupled with 3D CFD code, CONVERGE, to simulate the experimental data. The simulation results showed that the effects of physical properties on DE50 combustion are negligible. Simulations of DE50 mixture revealed that the combustion is nearly homogenous, while diesel (n-heptane used as a surrogate) and DE75 showed similar combustion behavior with flame liftoff and diffusion controlled combustion. Diesel exhibited auto-ignition at an equivalence ratio of 2, while DE75 and DE50 showed auto-ignition in the equivalence ratio range of 1-1.5 and 0-1, respectively. The experiments and numerical simulations demonstrate how the high reactivity of DEE supports the auto-ignition of ethanol, while ethanol acts as a radical scavenger.

Decolorization of C.I. Acid Blue 9 solution by UV/Nano-TiO2, Fenton, Fenton-like, electro-Fenton and electrocoagulation processes: A comparative study

International Nuclear Information System (INIS)

Khataee, A.R.; Vatanpour, V.; Amani Ghadim, A.R.

2009-01-01

This study makes a comparison between UV/Nano-TiO 2 , Fenton, Fenton-like, electro-Fenton (EF) and electrocoagulation (EC) treatment methods to investigate the removal of C.I. Acid Blue 9 (AB9), which was chosen as the model organic contaminant. Results indicated that the decolorization efficiency was in order of Fenton > EC > UV/Nano-TiO 2 > Fenton-like > EF. Desired concentrations of Fe 2+ and H 2 O 2 for the abatement of AB9 in the Fenton-based processes were found to be 10 -4 M and 2 x 10 -3 M, respectively. In the case of UV/Nano-TiO 2 process, we have studied the influence of the basic photocatalytic parameters such as the irradiation time, pH of the solution and amount of TiO 2 nanoparticles on the photocatalytic decolorization efficiency of AB9. Accordingly, it could be stated that the complete removal of color, after selecting desired operational parameters could be achieved in a relatively short time, about 25 min. Our results also revealed that the most effective decomposition of AB9 was observed with 150 mg/l of TiO 2 nanoparticles in acidic condition. The effect of operational parameters including current density, initial pH and time of electrolysis were studied in electrocoagulation process. The results indicated that for a solution of 20 mg/l AB9, almost 98% color were removed, when the pH was about 6, the time of electrolysis was 8 min and the current density was approximately 25 A/m 2 in electrocoagulation process

O modelo de Karl Popper sob a ótica das Ciências Sociais Aplicadas

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Milton de Abreu Campanario

2012-04-01

Full Text Available DOI: http://dx.doi.org/10.5007/2175-8077.2012v14n32p124 Karl Popper é o principal filósofo da ciência na modernidade, disputando com Thomas Kuhn a primazia de interpretação do método científico. Claramente há diferentes visões para uma leitura desse importante autor que cunhou o método chamado de dedutivo com teste. O texto reconhece a relevância da visão de Karl Popperno desenvolvimento de trabalhos científicos das ciências exatas e biológicas, onde é amplamente aceita. No entanto, nota-se que essa formulação é pouco sistematizada na área das ciências sociais aplicadas. Este é um ensaio que busca resgatar a sua contribuição, numa tentativa de traduzir os conceitos por ele desenvolvidos de forma didática. Para tanto, será feita uma introdução aos fundamentos da ciência como forma específica de conhecimento, buscando contrastar os métodos dedutivo e indutivo e os procedimentos da ciência formal, básica e aplicada. Uma tentativa de classificar a formulação de proposições a serem testadas ou falseadas é feita com a utilização de diferentes critérios, utilizando exemplos da administração e da economia para ilustração.

Por uma ciência formativa e indiciária: proposta epistemológica para a ciência da informação Formative science and indicial science: epistemological proposal for information science

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Eliany Alvarenga de Araújo

2006-01-01

Full Text Available Reflexão epistemológica sobre a Ciência da Informação como “fazer científico” que se estrutura na Ciência Moderna, em termos teóricos e metodológicos e nas Tecnologias daInformação, em termos aplicados. Tal configuração possibilitou o surgimento desta ciência, porém consideramos que a mesma não garantirá à mesma o pleno desenvolvimento comocampo de conhecimento consistente e moderno. A Ciência Moderna, enquanto visão e prática científica encontra-se esgotada e as Tecnologias de Informação são apenas mecanismos autoregulados que funcionam segundo princípios de automatismos. A partir destas considerações propomos o conceito de ciência formativa (Bachelard, 1996 e o paradigma indiciário (Ginzburg, 1991 como bases teóricas e metodológicas para uma epistemologia da Ciência da Informação. O conceito de ciência formativa se baseia no principio dos três estados do espírito científico e nas condições psicológicas do progresso científico e o paradigma indiciário propõe a intuição (empírica e racional como base metodológica para o fazer científico.Epistemological reflections on the Information Science as scientific field that if structure in the context of modern science, in theoretical and methodological terms and technologies of the information in applied terms. Such configuration made possible the sprouting of this science; however we consider that the same one will not guarantee to this science the full development as field of consistent and modern knowledge. Modern Science, while scientific practical vision and meets depleted and the information technologies are only auto-regulated mechanisms that function according to principles of automatisms. To leave of these considerations we propols the concept of Formative Science (Bachelard, 1996 and the Indiciario Paradigm (1991 with epistemological basis for the Information Science. The concept of formative science if a base on the principles of tree

Reduced dietary salt for the prevention of cardiovascular disease

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Alma J. Adler

of reduction (end of trial RR 0.67, 95% confidence interval (CI 0.40 to 1.12, 60 deaths; longest follow-up RR 0.90, 95% CI 0.58 to 1.40, 79 deaths n = 3518 or in hypertensives (end of trial RR 1.00, 95% CI 0.86 to 1.15, 565 deaths; longest follow-up RR 0.99, 95% CI 0.87 to 1.14, 674 deaths n = 3085. There was weak evidence of benefit for cardiovascular mortality (hypertensives: end of trial RR 0.67, 95% CI 0.45 to 1.01, 106 events n = 2656 and for cardiovascular events (hypertensives: end of trial RR 0.76, 95% CI 0.57 to 1.01, 194 events, four studies, n = 3397; normotensives: at longest follow-up RR 0.71, 95% CI 0.42 to 1.20, 200 events; hypertensives: RR 0.77, 95% CI 0.57 to 1.02, 192 events; pooled analysis of six trials RR 0.77, 95% CI 0.63 to 0.95, n = 5912. These findings were driven by one trial among retirement home residents that reduced salt intake in the kitchens of the homes, thereby not requiring individual behaviour change. Advice to reduce salt showed small reductions in systolic blood pressure (mean difference (MD -1.15 mmHg, 95% CI -2.32 to 0.02 n = 2079 and diastolic blood pressure (MD -0.80 mmHg, 95% CI -1.37 to -0.23 n = 2079 in normotensives and greater reductions in systolic blood pressure in hypertensives (MD -4.14 mmHg, 95% CI -5.84 to -2.43 n = 675, but no difference in diastolic blood pressure (MD -3.74 mmHg, 95% CI -8.41 to 0.93 n = 675. Overall many of the trials failed to report sufficient detail to assess their potential risk of bias. Health-related quality of life was assessed in one trial in normotensives, which reported significant improvements in well-being but no data were presented.AUTHORS' CONCLUSIONS: Despite collating more event data than previous systematic reviews of randomised controlled trials, there is insufficient power to confirm clinically important effects of dietary advice and salt substitution on cardiovascular mortality in normotensive or hypertensive populations. Our estimates of the clinical benefits from advice to

Enhanced response rates in pancreatic cancer with concurrent continuous infusion(CI) low dose chemotherapy and hyperfractionated radiotherapy

International Nuclear Information System (INIS)

Bronn, Donald G.; Franklin, Roman; Krishnan, Rajan S.; Richardson, Ralph W.; Conlin, Christopher

1996-01-01

Objective: Many patients with a diagnosis of pancreatic cancer are not offered any therapeutic intervention other than surgical bypass due to very poor prognosis, poor patient tolerance to current therapeutic regimens, and a dismal tumor response to therapy. In view of these circumstances, an acceptable treatment regimen for pancreatic cancer must first demonstrate an ability to obtain a rapid tumor response with a regimen that will be well tolerated enabling the patient to maintain a good quality of life with full ambulatory status. Materials and Methods: Nine unresectable pancreatic cancer patients ((4(9)) had liver metastases) with an average age of 62 (range: 41-79) were treated with a concurrent regimen consisting of 5-Fluorouracil (CI 200-250 mg/m 2 /24 hrs) and Cisplatin (CI 5mg/24 hrs: 2 weeks on, 1 week off) given simultaneously with 3-D planned BID hyperfractionated radiotherapy to the pancreas (5940 cGy/66 fractions/6.5 weeks), and whole liver (1980 cGy/22 fractions/2 weeks), plus additional dose to the partial liver in metastatic disease. Continuous infusion combination chemotherapy was continued alone after radiotherapy for a total of six months. Chemotherapy was delivered by dual light weight portable external pumps. Hyperalimentation was used as needed to maintain nutritional status and warfarin thromboembolic prophylaxis was also utilized. Tumor response was monitored by monthly abdominal CAT scans, serum markers (CEA, CA 19-9), weight gain, and symptomatology. Full radiographic resolution of tumor mass was considered to be a complete response (CR), whereas 50% or greater radiographic decrease in size was considered a partial response (PR). Evaluation was done by independent diagnostic radiologists. Results: CR and PR of the pancreatic mass was achieved in 88% of all patients ((8(9))). CR was achieved in 44% of all patients ((4(9))). Patients with liver metastases exhibited 75% ((3(4))) PR in liver masses and either CR or PR in the primary site. All

CI+MBPT calculations of Ar I energies, g factors, and transition line strengths

Science.gov (United States)

Savukov, I. M.

2018-03-01

Excited states of noble gas atoms present certain challenges to atomic theory for several reasons: first, relativistic effects are important and LS coupling is not optimal; second, energy intervals can be quite small, leading to strong mixing of states; third, many-body perturbation theory for hole states does not converge well. Previously, some attempts were made to solve this problem, using for example the all-order coupled-cluster approach and particle-hole configuration-interaction many-body perturbation theory (CI-MBPT) with modified denominators. However, while these approaches were promising, the accuracy was still limited. In this paper, we calculate Ar I energies, g factors, and transition amplitudes using ab initio CI-MBPT with eight valence electrons to avoid the problem of slow convergence of MBPT due to strong interaction between 3p and 3s states. We also included in CI many dominant states obtained by double excitations of the ground state configuration. Thus perturbation corrections were needed only for 1s, 2s, 2p core electrons non-included in valence-valence CI, which are quite small. We found that energy, g factors, and electric dipole matrix elements are in reasonable agreement with experiments. It is noteworthy that the theory agreed well with accurately measured g factors. Experimental oscillator strengths have large uncertainty, so in some cases we made a comparison with average values.

Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform

Science.gov (United States)

Moutsatsos, Ioannis K.; Hossain, Imtiaz; Agarinis, Claudia; Harbinski, Fred; Abraham, Yann; Dobler, Luc; Zhang, Xian; Wilson, Christopher J.; Jenkins, Jeremy L.; Holway, Nicholas; Tallarico, John; Parker, Christian N.

2016-01-01

High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such applications is challenging but highly valuable. Scientific data integration and pipelining facilitate standardized data processing, collaboration, and reuse of best practices. We describe how Jenkins-CI, an “off-the-shelf,” open-source, continuous integration system, is used to build pipelines for processing images and associated data from high-content screening (HCS). Jenkins-CI provides numerous plugins for standard compute tasks, and its design allows the quick integration of external scientific applications. Using Jenkins-CI, we integrated CellProfiler, an open-source image-processing platform, with various HCS utilities and a high-performance Linux cluster. The platform is web-accessible, facilitates access and sharing of high-performance compute resources, and automates previously cumbersome data and image-processing tasks. Imaging pipelines developed using the desktop CellProfiler client can be managed and shared through a centralized Jenkins-CI repository. Pipelines and managed data are annotated to facilitate collaboration and reuse. Limitations with Jenkins-CI (primarily around the user interface) were addressed through the selection of helper plugins from the Jenkins-CI community. PMID:27899692

Jenkins-CI, an Open-Source Continuous Integration System, as a Scientific Data and Image-Processing Platform.

Science.gov (United States)

Moutsatsos, Ioannis K; Hossain, Imtiaz; Agarinis, Claudia; Harbinski, Fred; Abraham, Yann; Dobler, Luc; Zhang, Xian; Wilson, Christopher J; Jenkins, Jeremy L; Holway, Nicholas; Tallarico, John; Parker, Christian N

2017-03-01

High-throughput screening generates large volumes of heterogeneous data that require a diverse set of computational tools for management, processing, and analysis. Building integrated, scalable, and robust computational workflows for such applications is challenging but highly valuable. Scientific data integration and pipelining facilitate standardized data processing, collaboration, and reuse of best practices. We describe how Jenkins-CI, an "off-the-shelf," open-source, continuous integration system, is used to build pipelines for processing images and associated data from high-content screening (HCS). Jenkins-CI provides numerous plugins for standard compute tasks, and its design allows the quick integration of external scientific applications. Using Jenkins-CI, we integrated CellProfiler, an open-source image-processing platform, with various HCS utilities and a high-performance Linux cluster. The platform is web-accessible, facilitates access and sharing of high-performance compute resources, and automates previously cumbersome data and image-processing tasks. Imaging pipelines developed using the desktop CellProfiler client can be managed and shared through a centralized Jenkins-CI repository. Pipelines and managed data are annotated to facilitate collaboration and reuse. Limitations with Jenkins-CI (primarily around the user interface) were addressed through the selection of helper plugins from the Jenkins-CI community.

Static Code Analysis with Gitlab-CI

CERN Document Server

Datko, Szymon Tomasz

2016-01-01

Static Code Analysis is a simple but efficient way to ensure that application’s source code is free from known flaws and security vulnerabilities. Although such analysis tools are often coming with more advanced code editors, there are a lot of people who prefer less complicated environments. The easiest solution would involve education – where to get and how to use the aforementioned tools. However, counting on the manual usage of such tools still does not guarantee their actual usage. On the other hand, reducing the required effort, according to the idea “setup once, use anytime without sweat” seems like a more promising approach. In this paper, the approach to automate code scanning, within the existing CERN’s Gitlab installation, is described. For realization of that project, the Gitlab-CI service (the “CI” stands for "Continuous Integration"), with Docker assistance, was employed to provide a variety of static code analysers for different programming languages. This document covers the gene...

40 CFR 60.4210 - What are my compliance requirements if I am a stationary CI internal combustion engine manufacturer?

Science.gov (United States)

2010-07-01

... I am a stationary CI internal combustion engine manufacturer? 60.4210 Section 60.4210 Protection of... CI internal combustion engine manufacturer? (a) Stationary CI internal combustion engine... certified to the standards in 40 CFR part 1039. (b) Stationary CI internal combustion engine manufacturers...

Commercial mitigation techniques used in remediating a 2200 pCi/L public building

International Nuclear Information System (INIS)

Davidson, J.G.

1990-01-01

This paper reports on commercial mitigation techniques used in remediating a 2200 pCi/L public building. In March of 1989 EPA and Pa. DER officials were amazed to discover a school in Pennsylvania with levels in its library of 2200 pCi/L. The library was a 30 year old, three story slab-on-grade structure more like a commercial building than a typical school structure. It had three separate and complex HVAC systems. Initial diagnostics indicated radon levels under the slab at over 80,000 pCi/L. Further investigations revealed major entry routes and a HVAC system terribly out of balance. Remediation consisted of installing a complex sub-slab depressurization system with an exterior commercial fan unit, major entry route sealing, and working closely with a mechanical contractor to bring the HVAC systems back into balance. Initial post remediation testing showed a 99% drop in radon levels. Refinements to the system are still in progress

Perfil dos Professores de Ciências Naturais do Recôncavo da Bahia - Alunos da Disciplina Terra e Universo no Curso de Ciências Naturais do Parfor

Science.gov (United States)

Lima, S. R.; Cerqueira Júnior, W.; Dutra, G.

2011-12-01

Este trabalho foi desenvolvido pelo projeto Astronomia no Recôncavo da Bahia, no Centro de Formação de Professores da Universidade Federal do Recôncavo da Bahia. Traçamos o perfil de um grupo de professores que lecionam conteúdos de Ciências Naturais no recôncavo, alunos do curso de Licenciatura em Ciências Naturais, oferecido dentro do Plano Nacional de Formação de Professores da Educação Básica. Nosso objetivo era avaliar se eles estão preparados para trabalhar conteúdos de Astronomia e identificar suas dificuldades. Os resultados serviram para orientar o professor da disciplina “Terra e Universo”, oferecida no segundo semestre de 2010. Durante a primeira aula da disciplina Terra e Universo, os alunos responderam a um questionário contendo questões abertas e fechadas, divididas em duas partes. A primeira procurando caracterizar profissionalmente os alunos enquanto professores da rede pública da região do Recôncavo Sul da Bahia e uma segunda parte procurando identificar conhecimentos básicos em Astronomia. Os resultados indicam uma predominância de professores do sexo feminino, com idade superior aos 40 anos, pardos e sem formação específica para o ensino de ciências. A maioria leciona há mais de 15 anos para turmas do 1º ao 5º ano, alguns lecionam para turmas de 6º ao 9º ano. Quase todos nunca participaram de um curso de formação continuada em Astronomia. Além disso, não estão habituados a ler revistas especializadas e nem livros com esta temática. Os que procuram ensinar temas voltados para a Astronomia têm, no livro didático, a maior fonte de informação sobre o assunto. As respostas também indicam uma deficiência em conteúdos básicos como a compreensão da esfericidade da Terra, noções de verticalidade e gravidade, incapacidade de identificar a Terra como um planeta, no Sistema Solar, em uma galáxia, no Universo. Estes resultados ressaltam a importância de disciplinas de Astronomia básica na formação dos

Regulation of notochord-specific expression of Ci-Bra downstream genes in Ciona intestinalis embryos.

Science.gov (United States)

Takahashi, Hiroki; Hotta, Kohji; Takagi, Chiyo; Ueno, Naoto; Satoh, Nori; Shoguchi, Eiichi

2010-02-01

Brachyury, a T-box transcription factor, is expressed in ascidian embryos exclusively in primordial notochord cells and plays a pivotal role in differentiation of notochord cells. Previously, we identified approximately 450 genes downstream of Ciona intestinalis Brachyury (Ci-Bra), and characterized the expression profiles of 45 of these in differentiating notochord cells. In this study, we looked for cisregulatory sequences in minimal enhancers of 20 Ci-Bra downstream genes by electroporating region within approximately 3 kb upstream of each gene fused with lacZ. Eight of the 20 reporters were expressed in notochord cells. The minimal enchancer for each of these eight genes was narrowed to a region approximately 0.5-1.0-kb long. We also explored the genome-wide and coordinate regulation of 43 Ci-Bra-downstream genes. When we determined their chromosomal localization, it became evident that they are not clustered in a given region of the genome, but rather distributed evenly over 13 of the 14 pairs of chromosomes, suggesting that gene clustering does not contribute to coordinate control of the Ci-Bra downstream gene expression. Our results might provide Insights Into the molecular mechanisms underlying notochord formation in chordates.

Trophic analysis of the fish community in the Ciénega Churince, Cuatro Ciénegas, Coahuila

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Ariana Hernández

2017-09-01

Full Text Available Fish diets were analyzed to evaluate the dynamic trophs of the fish community in the Churince wetland system of the Cuatro Ciénegas, where the fauna consists of nine species: endemic, native and introduced. In nine sampling events (between February 2011 and May 2014 556 specimens of all nine species were collected. Stomach contents were analyzed and the Relative Importance Index (IRI was calculated. The feed coefficient (Q of the diets and the accumulated trophic diversity (Hk, as well as the amplitude of the trophic niche were evaluated. Feeding strategies in the fish community were found to be eurifagic. The main foods in general were insects, crustaceans, gastropods, plants and teleosts. According to the average linkage method, four functional trophic groups were defined, with no higher consumption species; nevertheless all were regulators, mainly invertebrates. Therefore, the chain reaction in food control was higher from top to bottom, meaning a downwards dietary control.

Harnessing Neuroplasticity to Promote Rehabilitation: CI Therapy for TBI

Science.gov (United States)

2016-10-01

occasions, magnetic resonance imaging ( MRI ), diffusion tensor imaging (DTI), and functional MRI (fMRI) of the brain will be carried out to determine changes...to which types of neuroplasticity-inducing pharmacological agents, when combined with CI therapy, are most likely to yield a superior treatment...were negotiated with the Birmingham VAMC, Denver VAMC, and Richmond VAMC. • The option of collecting MRI data using a 1.5T scanner was added for

Preoperative apolipoprotein CI levels correlate positively with the proinflammatory response in patients experiencing endotoxemia following elective cardiac surgery

NARCIS (Netherlands)

Schippers, E.F.; Berbée, J.F.P.; Disseldorp, I.M. van; Versteegh, M.I.M.; Havekes, L.M.; Rensen, P.C.N.; Dissel, J.T. van

2008-01-01

Objective: Experimental models show that apolipoprotein CI (apoCI) binds and enhances the inflammatory response to endotoxin. We studied in patients undergoing cardiopulmonary bypass surgery (CPB) and experiencing endotoxemia during reperfusion whether plasma apoCI levels correlate with the

Klozapina: między skutecznością a bezpieczeństwem

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Tomasz Sobów

2015-07-01

Full Text Available Klozapina, choć uważana za bardzo skuteczny lek przeciwpsychotyczny, jest stosowana rzadziej, niż wynikałoby z przesłanek klinicznych wspierających jej stosowanie. Co najmniej 1/3 chorych ze schizofrenią spełnia kliniczne kryteria lekooporności, charakteryzuje się wysokim ryzykiem samobójstwa lub reaguje nasilonymi objawami pozapiramidowymi na inne leki przeciwpsychotyczne. Możliwym powodem relatywnie rzadkiego sięgania po klozapinę w praktyce klinicznej jest postrzeganie leku jako obarczonego poważnymi objawami niepożądanymi. Agranulocytoza i inne dyskrazje krwi są dobrze znane, a zasady prewencji – uporządkowane zaleceniami. O innych objawach niepożądanych, również tych potencjalnie niebezpiecznych (kardiomiopatia, zapalenia mięśnia sercowego, niedrożność jelit czy drgawki wiadomo mniej. Ryzyko wystąpienia groźnych powikłań kuracji klozapiną można jednak zminimalizować, a same powikłania – wykrywać i leczyć, pod warunkiem zachowania czujności diagnostycznej. Świadomość ryzyka i korzyści związanych ze stosowaniem klozapiny to warunek konieczny skutecznego i bezpiecznego użycia tego leku oraz pełnego wykorzystania jego niezwykłych właściwości.

A nova convergência da ciência e da tecnologia

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Esper A. Cavalheiro

2007-07-01

Full Text Available A ação sinérgica dos quatro campos científicos e tecnológicos que apresentaram crescimento acelerado nas últimas décadas - nanotecnologia, biotecnologia, tecnologias de comunicação e informação e ciências cognitivas (neurociência - tem sido intitulada Convergência Tecnológica. Este artigo faz uma revisão das principais discussões que vêm ocorrendo na comunidade científica internacional sobre o seu desenvolvimento e assinala a necessidade de uma abordagem mais ampla que inclua as ciências humanas e sociais e outros atores relevantes na sociedade contemporânea.The synergic combination of the scientific and technological fields that presented a rapid growth rate in the last few decades - nanotechnology, biotechnology, information and communication technologies, and cognitive science including neuroscience - is nowadays known as Convergent Technologies. This paper reviews its recent impact on the international scientific community and points out the need of amplifying the discussions to include humanities and social sciences and other important actors of contemporary society.

Palenie papierosów w ciąży = Cigarette smoking in pregnancy

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Agnieszka Konstancja Pawłowska-Muc

2016-01-01

4 Doctoral Candidate at the Department and Clinic of Gynaecology and Gynaecological Endocrinology, School of Health Studies, Medical University of Lublin, Al. Racławickie 23   Adres do korespondencji: mgr piel. Agnieszka Konstancja Pawłowska-Muc Ośrodek Kształcenia Podyplomowego Pielęgniarek i Położnych Radomski Szpital Specjalistyczny im. dr Tytusa Chałubińskiego w Radomiu, ul. Lekarska 4 tel. 48  3615616; fax: 48 3615437 e-mail: agmich@vp.pl   Streszczenie Wprowadzenie. Palenie papierosów jest dużym problemem zdrowotnym i społeczno – ekonomicznym. Stanowi zagrożenie dla rozrodu, przebiegu ciąży i zdrowia dziecka. Cel pracy. Ukazanie problemu palenia papierosów przez kobiety ciężarne na podstawie przeglądu piśmiennictwa.             Skrócony opis stanu wiedzy. W opracowaniu przedstawiono epidemiologię i skalę problemu oraz konsekwencje palenia w okresie ciąży, z uwzględnieniem podziału na przebieg ciąży i zdrowie dziecka. Omówiono też świadomość kobiet odnośnie negatywnych skutków takich zachowań. Podsumowanie. Z przeglądu piśmiennictwa wynika, że palenie papierosów przez kobiety ciężarne nie należy do rzadkości. Skala problemu nie jest łatwa do oceny, gdyż wiele z nich po prostu nie przyznaje się do tego. Negatywne konsekwencje palenia w ciąży są dość liczne i dotyczą zarówno jej przebiegu, jak i stanu noworodka oraz zdrowia dziecka w późniejszym okresie życia. Istnieje potrzeba kształtowania postaw antynikotynowych, zwłaszcza wśród dziewcząt i kobiet w wieku rozrodczym.   Słowa kluczowe: kobieta ciężarna, palenie papierosów w ciąży.                                                                   Summary Introduction. Smoking cigarettes is a major health and social-economical problem. It poses a threat to reproduction, parturition and the health of the baby. Aim. Illustrating the problem of smoking cigarettes by

Fałszywy znak równości

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Efraim Zuroff

2012-12-01

Full Text Available The equivalency canard Efraim Zuroff's text, originally published in Haaretz magazine, is a review of Timothy Snyder's Bloodlands. Snyder distinguishes six main mass murders commited by Nazi Germany and Soviet Union during the period of the Third Reich's existence. In Zuroff's opinion there are some significant differences between these tragedies. Dubious comparisons proposed by Snyder made the Holocaust most affected. Describing the Shoah as one of the six equally horryfying mass murders, the author ignores its ideological roots. Roots that sentenced to death all Jews  - regardless of their political views, religious practicies or the level of identification with Jewish community. Moreover Snyder takes no notice of the georaphical scope of the Holocaust. He also does not notice the fact, that the Nazis effectively managed to make so many Europeans their accomplices, who actively supported the Shoah.   Fałszywy znak równości Tekst Efraima Zuroffa, który pierwotnie ukazał się w piśmie Haaretz, to recenzja książki Skrwawione ziemie Timothy Snydera. Snyder wyróżnia sześć głównych masowych mordów popełnionych przez Niemcy i Związek Radziecki w okresie, który odpowiada istnieniu Trzeciej Rzeszy. Istnieją jednak, zdaniem Zuroffa, znaczące różnice między tymi tragediami. Na wątpliwych porównaniach, które proponuje Snyder, najbardziej „ucierpiał” Holokaust. Opisując Shoah jako jeden z sześciu równie straszliwych, masowych mordów, autor pomija jego ideologiczne korzenie, które sprawiały, że na śmierć skazany był każdy bez wyjątku Żyd, niezależnie od jego poglądów politycznych, praktyk religijnych czy stopnia identyfikacji z żydowską wspólnotą. Ponadto Snyder ignoruje ogromny zasięg geograficzny Holokaustu. Nie zauważa także skuteczności, z jaką naziści potrafili uczynić swoimi wspólnikami tak wielu Europejczyków, którzy w konsekwencji aktywnie wspomagali Shoah.

Direct Simple Shear Test Data Analysis using Jupyter Notebooks on DesignSafe-CI

Science.gov (United States)

Eslami, M.; Esteva, M.; Brandenberg, S. J.

2017-12-01

Due to the large number of files and their complex structure, managing data generated during natural hazards experiments requires scalable and specialized tools. DesignSafe-CI (https://www.designsafe-ci.org/) is a web-based research platform that provides computational tools to analyze, curate, and publish critical data for natural hazards research making it understandable and reusable. We present a use case from a series of Direct Simple Shear (DSS) experiments in which we used DS-CI to post-process, visualize, publish, and enable further analysis of the data. Current practice in geotechnical design against earthquakes relies on the soil's plasticity index (PI) to assess liquefaction susceptibility, and cyclic softening triggering procedures, although, quite divergent recommendations on recommended levels of plasticity can be found in the literature for these purposes. A series of cyclic and monotonic direct simple shear experiments was conducted on three low-plasticity fine-grained mixtures at the same plasticity index to examine the effectiveness of the PI in characterization of these types of materials. Results revealed that plasticity index is an insufficient indicator of the cyclic behavior of low-plasticity fine-grained soils, and corrections for pore fluid chemistry and clay minerology may be necessary for future liquefaction susceptibility and cyclic softening assessment procedures. Each monotonic, or cyclic experiment contains two stages; consolidation and shear, which include time series of load, displacement, and corresponding stresses and strains, as well as equivalent excess pore-water pressure. Using the DS-CI curation pipeline we categorized the data to display and describe the experiment's structure and files corresponding to each stage of the experiments. Two separate notebooks in Python 3 were created using the Jupyter application available in DS-CI. A data plotter aids visualizing the experimental data in relation to the sensor from which it was

Identification and Validation of Novel Hedgehog-Responsive Enhancers Predicted by Computational Analysis of Ci/Gli Binding Site Density

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Richards, Neil; Parker, David S.; Johnson, Lisa A.; Allen, Benjamin L.; Barolo, Scott; Gumucio, Deborah L.

2015-01-01

The Hedgehog (Hh) signaling pathway directs a multitude of cellular responses during embryogenesis and adult tissue homeostasis. Stimulation of the pathway results in activation of Hh target genes by the transcription factor Ci/Gli, which binds to specific motifs in genomic enhancers. In Drosophila, only a few enhancers (patched, decapentaplegic, wingless, stripe, knot, hairy, orthodenticle) have been shown by in vivo functional assays to depend on direct Ci/Gli regulation. All but one (orthodenticle) contain more than one Ci/Gli site, prompting us to directly test whether homotypic clustering of Ci/Gli binding sites is sufficient to define a Hh-regulated enhancer. We therefore developed a computational algorithm to identify Ci/Gli clusters that are enriched over random expectation, within a given region of the genome. Candidate genomic regions containing Ci/Gli clusters were functionally tested in chicken neural tube electroporation assays and in transgenic flies. Of the 22 Ci/Gli clusters tested, seven novel enhancers (and the previously known patched enhancer) were identified as Hh-responsive and Ci/Gli-dependent in one or both of these assays, including: Cuticular protein 100A (Cpr100A); invected (inv), which encodes an engrailed-related transcription factor expressed at the anterior/posterior wing disc boundary; roadkill (rdx), the fly homolog of vertebrate Spop; the segment polarity gene gooseberry (gsb); and two previously untested regions of the Hh receptor-encoding patched (ptc) gene. We conclude that homotypic Ci/Gli clustering is not sufficient information to ensure Hh-responsiveness; however, it can provide a clue for enhancer recognition within putative Hedgehog target gene loci. PMID:26710299

Inteligência Artificial, Tecnologias Informacionais E Seus Possíveis Impactos Sobre As Ciências Sociais

OpenAIRE

Dwyer T.

2001-01-01

Este artigo analisa algumas possibilidades de transformação das Ciências Sociais e, de maneira mais específica, na Sociologia, levantadas a partir do desenvolvimento e uso, nessas ciências, de tecnologias informacionais. Nas sociedades contemporâneas o aprofundamento do uso destas novas tecnologias pode trazer importantes conseqüências para as Ciências Sociais afetando, potencialmente, o ensino, a pesquisa e a construção de teoria. No Brasil podemos ver que um número crescente de informações ...

Prognozowanie i ujmowanie przychodóww przedsiębiorstwie postawionymw stan upadłości likwidacyjnej

OpenAIRE

Janusz Czerny

2010-01-01

W upadłości likwidacyjnej przedsiębiorstw mamy do czynienia z dwoma stru-mieniami przychodów, a mianowicie z przychodami dotyczącymi zbycia przedsię-biorstwa lub jego składników majątku oraz z przychodami związanymi z ewentual-nym kontynuowaniem działalności: Przychody ze sprzedaży przedsiębiorstwa powinny być prognozowane głównie na podstawie informacji płynących z systemu rachunkowości, co stanowi tzw. sta-tyczny aspekt upadłości, natomiast jej aspekt dynamiczny jest związany z zakre-sem...

Powikłania neurologiczne współistniejące z niewydolnością nerek

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Maria Łukasik

2010-03-01

Full Text Available Powikłania neurologiczne w przebiegu niewydolności nerek, zarówno te spowodowane mocznicą, jak i wynikające z jej leczenia, dotyczą ośrodkowego oraz obwodowego układu nerwowego, jak również tkanki mięśniowej i stanowią przyczynę zwiększonej śmiertelności u chorych z niewydolnością nerek. Pacjenci z niewydolnością nerek są szczególnie narażeni na rozwój encefalopatii mocznicowej, encefalopatii nadciśnieniowej, chorób naczyniowych ośrodkowego układu nerwowego bądź zespołów otępiennych. W tej grupie chorych częściej niż w populacji ogólnej rozwijają się mono- i polineuropatie, a choroby nerek należą do częstszych przyczyn zespołu niespokojnych nóg. Pomimo ciągłego postępu terapeutycznego wciąż nie ma skutecznego leczenia wielu tych powikłań, m.in. encefalopatii mocznicowej, miażdżycy, neuropatii czy miopatii. Co więcej, wprowadzenie dializoterapii rozszerzyło spektrum komplikacji o otępienie dializacyjne, krwawienia śródczaszkowe, zespół nierównowagi dializacyjnej, encefalopatię Wernickego i osmotyczną mielinolizę. Leczenie immunosupresyjne stosowane zarówno w chorobach nerek, jak i u chorych po przeszczepie nerki przyczyniło się do rozwoju oportunistycznych infekcji i nowotworzenia w ośrodkowym układzie nerwowym, ponadto niekiedy powikłane jest rozwojem odwracalnej tylnej leukoencefalopatii. Znajomość tych powikłań oraz ścisła współpraca między nefrologami i neurologami mogą przyczynić się do zmniejszenia śmiertelności i poprawy jakości życia chorych z niewydolnością nerek. Należy przy tym pamiętać, że także patologie, które prowadzą do niewydolności nerek (szczególnie choroby układowe tkanki łącznej czy cukrzyca, powodują uszkodzenia ośrodkowego i obwodowego układu nerwowego, a określenie rzeczywistej przyczyny bywa niemożliwe.

Geochemistry of CI chondrites: Major and trace elements, and Cu and Zn Isotopes

Science.gov (United States)

Barrat, J. A.; Zanda, B.; Moynier, F.; Bollinger, C.; Liorzou, C.; Bayon, G.

2012-04-01

In order to check the heterogeneity of the CI chondrites and determine the average composition of this group of meteorites, we analyzed a series of six large chips (weighing between 0.6 and 1.2 g) of Orgueil prepared from five different stones. In addition, one sample from each of Ivuna and Alais was analyzed. Although the sizes of the chips used in this study were “large”, our results show evidence for minor chemical heterogeneity in Orgueil, particularly for alkali elements and U. After removal of one outlier sample, the spread of the results is considerably reduced. For most of the 46 elements analyzed in this study, the average composition calculated for Orgueil is in very good agreement with previous CI estimates. This average, obtained with a “large” mass of samples, is analytically homogeneous and is suitable for normalization purposes. Finally, the Cu and Zn isotopic ratios are homogeneously distributed within the CI parent body with a spread of less than 100 ppm per atomic mass unit (amu).

Determination of drug, excipients and coating distribution in pharmaceutical tablets using NIR-CI

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Anna Palou

2012-04-01

Full Text Available The growing interest of the pharmaceutical industry in Near Infrared-Chemical Imaging (NIR-CI is a result of its high usefulness for quality control analyses of drugs throughout their production process (particularly of its non-destructive nature and expeditious data acquisition. In this work, the concentration and distribution of the major and minor components of pharmaceutical tablets are determined and the spatial distribution from the internal and external sides has been obtained. In addition, the same NIR-CI allowed the coating thickness and its surface distribution to be quantified. Images were processed to extract the target data and calibration models constructed using the Partial Least Squares (PLS algorithms. The concentrations of Active Pharmaceutical Ingredient (API and excipients obtained for uncoated cores were essentially identical to the nominal values of the pharmaceutical formulation. But the predictive ability of the calibration models applied to the coated tablets decreased as the coating thickness increased. Keywords: Near infrared Chemical Imaging (NIR-CI, Hyperspectral imaging, Component distribution, Tablet coating distribution, Partial Least Squares (PLS regression

Current status of the Citrus leprosis virus (CiLV -C and its vector Brevipalpus phoenicis (Geijskes

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Guillermo León M

2012-08-01

Full Text Available The Citrus leprosis virus CiLV-C is a quarantine disease of economic importance. Over the past 15 years, this disease has spread to several countries of Central and South America. Colombia has about 45,000 hectares of citrus planted with an annual production of 750,000 tonnes. The CiLV-C has only been detected in the departments of Meta, Casanare and recently Tolima. Meta has 4,300 hectares representing 10% of the national cultivated area, and Casanare, where CiLV-C appeared in 2004, has no more than 500 ha planted with citrus. The presence of the Citrus leprosis virus in Colombia could affect the international market for citrus, other crops and ornamental plants with the United States and other countries without the disease. The false spider mite Brevipalpus phoenicis (Geijskes (Acari: Tenuipalpidae is the main vector of the CiLV-C. Disease management is based on control programs of the vector and diminishing host plants. Chemical mite control is expensive, wasteful and generates resistance to different acaricides. This paper provides basic information on CiLV-C and its vector, advances in diagnosis and methods to control the disease and prevention of its spread

A crítica de Charles Taylor ao naturalismo na Ciência Política

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Tiago Losso

2011-06-01

Full Text Available Os mais recentes esforços de revitalização do enfoque interpretativo na Ciência Política têm sua gênese na década de 1960, quando vários autores passaram a advogar a centralidade do estudo dos significados lingüístico e hermenêutico dos fenômenos políticos. Dentre tais autores, destaca-se o filósofo e politólogo Charles Taylor, cujos textos dos anos 1960 e 1970 desferem críticas contundentes ao naturalismo subjacente ao mainstream da Ciência Política da época. Meu objetivo é explorar a crítica de Taylor ao naturalismo, pensadas no contexto de uma proposta de abordagem interpretativa para a Ciência Política. Primeiramente, contextualizarei as contribuições de Taylor no âmbito mais amplo do interpretive turn nas Ciências Sociais. Em seguida, sumarizarei as reservas que Quentin Skinner e Clifford Geertz apresentam à crítica de Taylor.

BADANIE MIESZANEK MINERALNO-ASFALTOWYCH W WARUNKACH ŚCINANIA PRZY KONTROLOWANEJ SZTYWNOŚCI WZDŁUŻNEJ

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Adam ZOFKA

2016-07-01

Full Text Available W artykule przedstawiono koncepcję nowej metody badania próbek z mieszanki mineralno-asfaltowej w warunkach ścinania z ciśnieniem bocznym. Dotychczas stosowane metody badawcze ścinania z obciążeniem bocznym opierają się na ocenie właściwości mieszanki mineralno-asfaltowej przy ścinaniu w warunkach stałej siły wzdłużnej lub stałej objętości badanej próbki. Nowa metoda badawcza pozwala na badanie ścinania przy stałej sztywności wzdłużnej. Aby możliwe było badanie według tej metody, zaprojektowano i wykonano specjalną przystawkę o nazwie AST (ang. Advanced Shear Tester. W artykule przedstawiono zarówno opis procesu twórczego podczas projektowania przystawki, jak wykonane urządzenie. Zaprezentowano pierwsze wyniki badań walidacyjnych uzyskanych przy użyciu przystawki na próbkach UHMW-PE oraz z mieszanki mineralno-asfaltowej.

Preferowanie podmiotów publicznych w niektórych rodzajach działalności gospodarczej

OpenAIRE

Sylwestrzak, Dorota

2015-01-01

Ustawodawca stwarza warunki zapewniające niedyskryminacyjne tratowanie podmiotów publicznych i prywatnych, ale zdarza się różnicowanie podmiotów, podyktowane zasadniczo przesłanką interesu publicznego i koniecznością ochrony wartości konstytucyjnych, Faworyzowanie podmiotów publicznych przejawia się głównie w zakresie stwarzania ułatwień w podejmowaniu działalności gospodarczej, w wyborze formy organizacyjno-prawnej, w której działalność gospodarcza może być prowadzona,...

Spacecraft COst REduction Team (SCORE): TQM/CI on a massive scale

Science.gov (United States)

Bullard, Jerry D.

1992-01-01

The business of building satellites and space systems has matured. Few missions require, or can afford, excellent performance at any price. The new paradigm is doing more with less, providing quality systems at lower cost--in other words, doing our job 'Faster-Better-Cheaper.' The TRW Spacecraft COst REduction (SCORE) initiative was launched in 1990 by Daniel S. Goldin, then general manager of TRW's Space & Technology Group. The SCORE mission is to apply continuous improvement (CI) techniques to effect major reductions in the cost (our primary goal) and span time (as a corollary) required for the production of spacecraft. SCORE is a multi-year initiative that is having a profound effect on both the procedural and the cultural aspects of how we do business. The objectives of this initiative are being realized. The focus of this paper is not on the results of SCORE per se, but rather on the things we have leaned about how to do continuous improvement on a massive scale, with multilevel (hierarchical) CI teams. The following sections summarize the chronology of the SCORE initiative, from team formation to development of the year-end report for 1991. Lessons learned, the core of this presentation, are discussed--with particular focus on the unique aspects of SCORE. The SCORE initiative is continuing and, as a part of our evolving culture, will never end. It has resulted in profound insights into the way we do work and (the topic at hand) how to do CI for large and complex multidisciplinary development activities.

Perfluoroalkyl Substances, Sex Hormones, and Insulin-like Growth Factor-1 at 6–9 Years of Age: A Cross-Sectional Analysis within the C8 Health Project

Science.gov (United States)

Lopez-Espinosa, Maria-Jose; Mondal, Debapriya; Armstrong, Ben G.; Eskenazi, Brenda; Fletcher, Tony

2016-01-01

Background: Exposure to some perfluoroalkyl substances (PFAS), such as perfluorohexane sulfonate (PFHxS), perfluorooctanoate (PFOA), perfluorooctane sulfonate (PFOS), and perfluorononanoic acid (PFNA), may alter levels of sex hormones and insulin-like growth factor-1 (IGF-1) in animals. Human studies on this topic are scarce, and none have been conducted in young children. Objectives: We investigated the relationship between levels of PFAS and estradiol, total testosterone, and IGF-1 in 2,292 children (6–9 years of age) from the C8 Health Project who lived near a chemical plant in the Mid-Ohio Valley (USA) with local contamination from PFOA. Methods: Serum samples were collected in 2005–2006 and analyzed for PFAS, sex hormones, and IGF-1. Results from regression models were expressed as the adjusted percentage difference (95% CI) per sex-specific interquartile range (IQR) increment of each PFAS serum concentration. Analyses by PFAS quartiles were also conducted. Results: Median concentrations of PFHxS, PFOA, PFOS, and PFNA were 8, 35, 22, and 1.7 ng/mL in boys and 7, 30, 21, and 1.7 ng/mL in girls. In boys, PFOA concentrations were significantly associated with testosterone levels (–4.9%; 95% CI: –8.7, –0.8%); PFOS with estradiol (–4.0%; 95% CI: –7.7, –0.1%), testosterone (–5.8%; 95% CI: –9.4, –2.0%), and IGF-1 (–5.9%; 95% CI: –8.3, –3.3%); and PFNA with IGF-1 (–3.5%; 95% CI: –6.0, –1.0%). In girls, significant associations were found between PFOS and testosterone (–6.6%; 95% CI: –10.1, –2.8%) and IGF-1 (–5.6%; –8.2, –2.9%); and PFNA and IGF-1 (–3.8%; 95% CI: –6.4, –1.2%). In both sexes, the magnitudes of the associations decreased monotonically across quartiles for both testosterone and IGF-1 in relation to PFOS, and for IGF-1 and PFNA in girls. Conclusions: To our knowledge, this is the first study suggesting that PFAS are associated with lower levels of IGF-1 and sex hormones in young children. Citation: Lopez

Combustion Characteristics of CI Diesel Engine Fuelled With Blends of Jatropha Oil Biodiesel

Science.gov (United States)

Singh, Manpreet; Yunus Sheikh, Mohd.; Singh, Dharmendra; Nageswara rao, P.

2018-03-01

Jatropha Curcas oil is a non-edible oil which is used for Jatropha biodiesel (JBD) production. Jatropha biodiesel is produced using transesterification technique and it is used as an alternative fuel in CI diesel engine without any hardware modification. Jatropha biodiesel is used in CI diesel engine with various volumetric concentrations (blends) such as JBD5, JBD15, JBD25, JBD35 and JBD45. The combustion parameters such as in-cylinder pressure, rate of pressure rise, net heat release, cumulative heat release, mass fraction burned are analyzed and compared for all blends combustion data with mineral diesel fuel (D100).

Multicentre evaluation of the Naída CI Q70 sound processor: feedback from cochlear implant users and professionals

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Jeanette Martin

2016-12-01

Full Text Available The aim of this survey was to gather data from both implant recipients and professionals on the ease of use of the Naída CI Q70 (Naída CI sound processor from Advanced Bionics and on the usefulness of the new functions and features available. A secondary objective was to investigate fitting practices with the new processor. A comprehensive user satisfaction survey was conducted in a total of 186 subjects from 24 centres. In parallel, 23 professional questionnaires were collected from 11 centres. Overall, there was high satisfaction with the Naída CI processor from adults, children, experienced and new CI users as well as from professionals. The Naída CI processor was shown as being easy to use by all ages of recipients and by professionals. The majority of experienced CI users rated the Naída CI processor as being similar or better than their previous processor in all areas surveyed. The Naída CI was recommended by the professionals for fitting in all populations. Features like UltraZoom, ZoomControl and DuoPhone would not be fitted to very young children in contrast to adults. Positive ratings were obtained for ease of use, comfort and usefulness of the new functions and features of the Naída CI sound processor. Seventy-seven percent of the experienced CI users rated the new processor as being better than their previous sound processor from a general point of view. The survey also showed that fitting practices were influenced by the age of the user.

Trudności terapeutyczne u pacjenta z ciężką postacią młodzieńczego zapalenia skórno-mięśniowego powikłanego uogólnioną wapnicą

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Joanna Szymańska-Kałuża

2011-08-01

Full Text Available Młodzieńcze zapalenie skórno-mięśniowe (MZSM to najczęstszaidiopatyczna miopatia zapalna wieku dziecięcego. Do charakterystycznychobjawów tej choroby należą: osłabienie mięśni, głównieobręczy barkowej lub biodrowej, oraz zmiany skórne w postaciobrzęku twarzy, heliotropowego zabarwienia powiek, zmian plamisto-rumieniowych na twarzy i klatce piersiowej. W badaniachlaboratoryjnych typowe dla MZSM są podwyższone wskaźnikiostrej fazy, wysoka aktywność enzymów mięśniowych (aminotransferaz,kinazy kreatynowej oraz dehydrogenazy mleczanowej,a także czasami obecność przeciwciał anty-Jo1. Badanie elektromiograficznewykazuje cechy pierwotnego uszkodzenia mięśni,a w obrazie histopatologicznym wycinka skórno-mięśniowegoodnotowuje się nacieki zapalne. U dzieci często obserwowane sątakże ogniska zwapnień w tkankach miękkich, prowadzące doatrofii mięśni i przykurczów stawowych.Leczeniem I rzutu u pacjentów z MZSM są glikokortykosteroidy,w przypadku nieskuteczności tej terapii stosuje się leki immunosupresyjnelub leki biologiczne, w tym immunoglobuliny.W pracy przedstawiono przypadek pacjenta z ciężkim przebiegiemMZSM powikłanego wapnicą, z uwzględnieniem objawów klinicznychi możliwości leczenia. Omówiono również trudności w doborzenajskuteczniejszej farmakoterapii dla tego pacjenta. U chorego– obecnie 14-letniego chłopca – występowały uogólnione zmianyskórne oraz bardzo gwałtownie narastające liczne złogi soli wapniaw skórze, tkance podskórnej, powięziach i mięśniach, które pojawiły się po 3 latach od wystąpienia pierwszych objawów chorobowych(ryc. 1–8. U chłopca z powodu wybitnie ciężkiego przebieguchoroby prowadzono agresywną konwencjonalną terapię(glikokortykosteroidy, metotreksat, cyklosporyna, pamidronian,która nie przynosiła zadowalających rezultatów i poprawy stanuklinicznego. Na podstawie doniesień z piśmiennictwa światowegopodjęto próbę leczenia

Determining the Optimum Cut-Off Grades in Sulfide Copper Deposits / Określanie Optymalnej Wartości Odcięcia Zawartości Procentowej Pierwiastka Użytecznego W Złożach Siarczku Miedzi

Science.gov (United States)

Rahimi, Esmaeil; Oraee, Kazem; Shafahi, Zia Aldin; Ghasemzadeh, Hasan

2015-03-01

Optimum cut-off grades determination in mining life affects production planning and ultimate pit limit and it is also important from social, economical and environmental aspects. Calculation of optimum cut-off grades has been less considered for mines containing various mineral processing methods. In this paper, an optimization technique is applied to obtain optimum cut-off grades for both concentration and heap leaching processes. In this technique, production costs and different recoveries of heap leaching method directed into modeling different annual cash flows in copper mines. Considering the governing constraints, the Lagrange multiplier method is practiced to optimize the cut-off grades in which the objective function is supposed to maximize Net Present Value. The results indicate the effect of heap leaching process on the optimum cut-off grades of primary and secondary sulfide deposits. Określanie optymalnego poziomu odcięcia dla zawartości procentowej pierwiastka użytecznego ma poważny wpływ na planowanie produkcji, określanie ostatecznych limitów zasobów złoża; jest to także ważna kwestia z punktu widzenia kwestii społecznych, ekonomicznych i środowiskowych. Obliczanie optymalnego poziomu odcięcia dla zawartości procentowej pierwiastka użytecznego nie było zwykle szeroko rozważane w przypadku kopalni prowadzących ciągły system przeróbki. W pracy tej przedstawiono technikę optymalizacji określania poziomu zawartości procentowej pierwiastka użytecznego z uwzględnieniem zarówno procesów koncentracji jak i ługowania. W metodzie uwzględniono koszty produkcji i różne wskaźniki odzysku rudy, wielkości te wykorzystane zostały do modelowania rocznych przepływów gotówki w kopalniach miedzi. Uwzględniając narzucone ograniczenia, zastosowano metodę mnożników Lagrange'a w celu optymalizacji określania poziomu zawartości procentowej pierwiastka użytecznego, gdzie przyjętą funkcją celu jest maksymalizacja wartości bie

Effect of operational parameters on the decolorization of C.I. Reactive Blue 19 in aqueous solution by ozone-enhanced electrocoagulation

Energy Technology Data Exchange (ETDEWEB)

Song Shuang; Yao Jie [College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032 (China); He Zhiqiao [College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032 (China)], E-mail: zqhe@zjut.edu.cn; Qiu Jianping; Chen Jianmeng [College of Biological and Environmental Engineering, Zhejiang University of Technology, Hangzhou 310032 (China)

2008-03-21

The aim of this paper was to investigate the efficiency of the ozone-enhanced electrocoagulation (EC) process in the decolorization of C.I. Reactive Blue 19 in water using iron electrodes. We determined the effects of various operating parameters such as initial pH, initial dye concentration, current density, salt concentration, temperature, ozone flow rate, and distance between electrodes on decolorization efficiency in a laboratory-scale reactor. Increasing the initial dye concentration decreased the decolorization efficiency, whereas increasing the distance between electrodes increased it. The other operating factors had both positive and negative effects. With an initial pH of 10.0, an initial dye concentration of 100 mg/L, current density of 10 mA/cm{sup 2}, salt concentration of 3000 mg/L, temperature of 30 deg. C, ozone flow rate of 20 mL/min, and distance between electrodes of 3 cm, over 96% of the color was removed after 10 min. As a consequence, removal of total organic carbon (TOC) was over 80%.

Effect of operational parameters on the decolorization of C.I. Reactive Blue 19 in aqueous solution by ozone-enhanced electrocoagulation

International Nuclear Information System (INIS)

Song Shuang; Yao Jie; He Zhiqiao; Qiu Jianping; Chen Jianmeng

2008-01-01

The aim of this paper was to investigate the efficiency of the ozone-enhanced electrocoagulation (EC) process in the decolorization of C.I. Reactive Blue 19 in water using iron electrodes. We determined the effects of various operating parameters such as initial pH, initial dye concentration, current density, salt concentration, temperature, ozone flow rate, and distance between electrodes on decolorization efficiency in a laboratory-scale reactor. Increasing the initial dye concentration decreased the decolorization efficiency, whereas increasing the distance between electrodes increased it. The other operating factors had both positive and negative effects. With an initial pH of 10.0, an initial dye concentration of 100 mg/L, current density of 10 mA/cm 2 , salt concentration of 3000 mg/L, temperature of 30 deg. C, ozone flow rate of 20 mL/min, and distance between electrodes of 3 cm, over 96% of the color was removed after 10 min. As a consequence, removal of total organic carbon (TOC) was over 80%

Report on the effectiveness of flocculation for removal of 239Pu at concentrations of 1 pCi/L and 0.1 pCi/L

International Nuclear Information System (INIS)

Triay, I.R.; Bayhurst, G.K.; Mitchell, A.J.; Cisneros, M.R.; Efurd, D.W.; Roensch, F.R.; Rokop, D.J.; Aguilar, R.D.; Attrep, M.; Nuttall, H.E.

1993-01-01

The objective of this work is to assess the effectiveness of flocculation for the removal of Pu from Rocky Flats Plant (RFP) pond waters spiked with 239 Pu at the 1.0 and 0.1 pCi/L level. The flocculation treatment procedure is described in detail. Results are presented for treatment studies for the removal of Pu from C-2 pond water spiked with 239 Pu and from distilled water spiked with 239 Pu

Aktywność fizyczna kobiet w ciąży w świadomości przyszłych instruktorów rekreacji ruchowej = Physical activity of expecting mothers in the awareness of future exercise professionals

OpenAIRE

Aneta Worska; Anna Szumilewicz

2015-01-01

Streszczenie             Kobiety ciężarne coraz częściej podejmują aktywność fizyczną, z której czerpią wielokierunkowe korzyści bez negatywnych konsekwencji dla zdrowia dziecka. Regurlarne zajęcia ruchowe w ciąży pozwalają m.in. zachować sprawność ciała, zapobiegają nadmiernemu przyrostowi masy ciała, ułatwiają poród oraz skracają czas połogu. Przed rozpoczęciem ćwiczeń konieczna jest nie tylko konsultacja z lekarzem, ale również z instruktorem zajęć ruchowych, by dobrać odpowiedni rodza...

Structural and functional properties of chimeric EspA-FliCi filaments of EPEC.

Science.gov (United States)

Crepin, Valerie F; Martinez, Eric; Shaw, Robert K; Frankel, Gad; Daniell, Sarah J

2008-04-18

Enteropathogenic Escherichia coli utilise a filamentous type III secretion system to translocate effector proteins into host gut epithelial cells. The primary constituent of the extracellular component of the filamentous type III secretion system is EspA. This forms a long flexible helical conduit between the bacterium and host and has a structure almost identical to that of the flagella filament. We have inserted the D3 domain of FliCi (from Salmonella typhimurium) into the outer domain of EspA and have studied the structure and function of modified filaments when expressed in an enteropathogenic E. coli espA mutant. We found that the chimeric protein EspA-FliCi filaments were biologically active as they supported protein secretion and translocation [assessed by their ability to trigger actin polymerisation beneath adherent bacteria (fluorescent actin staining test)]. The expressed filaments were recognised by both EspA and FliCi antisera. Visualisation and analysis of the chimeric filaments by electron microscopy after negative staining showed that, remarkably, EspA filaments are able to tolerate a large protein insertion without a significant effect on their helical architecture.

Combustion Homogeneity and Emission Analysis during the Transition from CI to HCCI for FACE I Gasoline

KAUST Repository

Vedharaj, S.

2017-10-10

Low temperature combustion concepts are studied recently to simultaneously reduce NOX and soot emissions. Optical studies are performed to study gasoline PPC in CI engines to investigate in-cylinder combustion and stratification. It is imperative to perform emission measurements and interpret the results with combustion images. In this work, we attempt to investigate this during the transition from CI to HCCI mode for FACE I gasoline (RON = 70) and its surrogate, PRF70. The experiments are performed in a single cylinder optical engine that runs at a speed of 1200 rpm. Considering the safety of engine, testing was done at lower IMEP (3 bar) and combustion is visualized using a high-speed camera through a window in the bottom of the bowl. From the engine experiments, it is clear that intake air temperature requirement is different at various combustion modes to maintain the same combustion phasing. While a fixed intake air temperature is required at HCCI condition, it varies at PPC and CI conditions between FACE I gasoline and PRF70. Three zones are identified 1) SOI = -180 to -80 CAD (aTDC) is HCCI zone 2) SOI = -40 to -20 CAD (aTDC) is PPC zone 3) After SOI = -15 CAD (aTDC) is CI zone. Combustion duration, ignition delay, start of combustion and CA90 (crank angle at which 90% of fuel burnt) are comparable between FACE I gasoline and PRF70. The combustion images show a prominent soot flame at CI condition, while only blue coloured premixed flames are visible at PPC condition for both the fuels. PRF70 seems to have a pronounced premixed effect when compared to FACE I gasoline at early injections, showing a decreased level of stratification. NOX emission and soot concentration decreases from CI condition and attains a constant zero value at HCCI condition for both FACE I gasoline and PRF70. CO and CO2 emissions matches between FACE I gasoline and PRF70 at PPC and CI condition, while CO emission is lower for PRF70 at HCCI condition.

Combustion Homogeneity and Emission Analysis during the Transition from CI to HCCI for FACE I Gasoline

KAUST Repository

Vedharaj, S.; Vallinayagam, R; An, Yanzhao; Izadi Najafabadi, Mohammad; Somers, Bart; Chang, Junseok; Johansson, Bengt

2017-01-01

Low temperature combustion concepts are studied recently to simultaneously reduce NOX and soot emissions. Optical studies are performed to study gasoline PPC in CI engines to investigate in-cylinder combustion and stratification. It is imperative to perform emission measurements and interpret the results with combustion images. In this work, we attempt to investigate this during the transition from CI to HCCI mode for FACE I gasoline (RON = 70) and its surrogate, PRF70. The experiments are performed in a single cylinder optical engine that runs at a speed of 1200 rpm. Considering the safety of engine, testing was done at lower IMEP (3 bar) and combustion is visualized using a high-speed camera through a window in the bottom of the bowl. From the engine experiments, it is clear that intake air temperature requirement is different at various combustion modes to maintain the same combustion phasing. While a fixed intake air temperature is required at HCCI condition, it varies at PPC and CI conditions between FACE I gasoline and PRF70. Three zones are identified 1) SOI = -180 to -80 CAD (aTDC) is HCCI zone 2) SOI = -40 to -20 CAD (aTDC) is PPC zone 3) After SOI = -15 CAD (aTDC) is CI zone. Combustion duration, ignition delay, start of combustion and CA90 (crank angle at which 90% of fuel burnt) are comparable between FACE I gasoline and PRF70. The combustion images show a prominent soot flame at CI condition, while only blue coloured premixed flames are visible at PPC condition for both the fuels. PRF70 seems to have a pronounced premixed effect when compared to FACE I gasoline at early injections, showing a decreased level of stratification. NOX emission and soot concentration decreases from CI condition and attains a constant zero value at HCCI condition for both FACE I gasoline and PRF70. CO and CO2 emissions matches between FACE I gasoline and PRF70 at PPC and CI condition, while CO emission is lower for PRF70 at HCCI condition.

In-cylinder Combustion and Soot Evolution in the Transition from Conventional CI mode to PPC

KAUST Repository

An, Yanzhao

2018-01-09

The present study intends to explore the in-cylinder combustion and evolution of soot emission during the transition from conventional compression ignition (CI) combustion to partially premixed combustion (PPC) at low load conditions. In-cylinder combustion images and engine-out emissions were measured in an optical engine fueled with low octane heavy naphtha fuel (RON = 50). Full cycle engine simulations were performed using a three-dimensional computational fluid dynamics code CONVERGETM, coupled with gas phase chemical kinetics, turbulence, and particulate size mimic soot model. The simulations were performed under low load conditions (IMEP ~ 2 to 3 bar) at an engine speed of 1200 rpm. The start of injection (SOI) was advanced from late (-10 CAD aTDC) to early fuel injection timings (-40 CAD aTDC) to realize the combustion transition from CI combustion to PPC. The simulation results of combustion and emission are compared with the experimental results at both CI and PPC combustion modes. The results of the study show a typical low-temperature stratified lean combustion at PPC mode, while high-temperature spray-driven combustion is evident at CI mode. The in-cylinder small intermediates species such as acetylene (C2H2), propargyl (C3H3), cyclopentadienyl (C5H5) and polycyclic aromatic hydrocarbons (PAHs) were significantly suppressed at PPC mode. Nucleation reaction of PAHs collision contributed to main soot mass production. The distribution of soot mass and particle number density was consistent with the distribution of high-temperature zones at CI and PPC combustion modes.

Ciência e arte: relações improváveis? Science and art: unlikely relations?

Directory of Open Access Journals (Sweden)

José Claudio Reis

2006-10-01

Full Text Available Este artigo discute as relações entre ciência e arte, principalmente entre física e pintura, com o objetivo de apresentar uma abordagem cultural para a ciência. Dessa forma, entendemos que a compreensão dos conteúdos da ciência torna-se mais significativa. Abordamos diferentes momentos da história desde a revolução científica até o século XX. As relações aqui salientadas não buscam uma relação causal entre ciência e arte, mas sim uma visão mais significativa do que é o processo de construção do conhecimento. Assim, a ciência se desnuda para nós como parte da cultura e pode nos ajudar a compreender melhor o processo histórico que nos trouxe até aqui.With the goal of presenting a cultural approach to science, the article discusses relations between science and art, especially between physics and painting. From this standpoint, we can see how understanding the substance of science becomes more important. Different moments in history are examined, from the scientific revolution down through the twentieth century. The relations highlighted herein are not chosen in an effort to undercover a causal relation between science and art but to arrive at a more meaningful understanding of how knowledge is constructed. Science is thus revealed to be part of culture, which can help us better understand the historical process through which we have come to this point.

Decolorization of C.I. Acid Blue 9 solution by UV/Nano-TiO{sub 2}, Fenton, Fenton-like, electro-Fenton and electrocoagulation processes: A comparative study

Energy Technology Data Exchange (ETDEWEB)

Khataee, A.R. [Water and Wastewater Treatment Research Laboratory, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz (Iran, Islamic Republic of)], E-mail: a_khataee@tabrizu.ac.ir; Vatanpour, V. [Water and Wastewater Treatment Research Laboratory, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz (Iran, Islamic Republic of)], E-mail: vahidvatanpoor@yahoo.com; Amani Ghadim, A.R. [Water and Wastewater Treatment Research Laboratory, Department of Applied Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz (Iran, Islamic Republic of)], E-mail: a.r_amani@yahoo.com

2009-01-30

This study makes a comparison between UV/Nano-TiO{sub 2}, Fenton, Fenton-like, electro-Fenton (EF) and electrocoagulation (EC) treatment methods to investigate the removal of C.I. Acid Blue 9 (AB9), which was chosen as the model organic contaminant. Results indicated that the decolorization efficiency was in order of Fenton > EC > UV/Nano-TiO{sub 2} > Fenton-like > EF. Desired concentrations of Fe{sup 2+} and H{sub 2}O{sub 2} for the abatement of AB9 in the Fenton-based processes were found to be 10{sup -4} M and 2 x 10{sup -3} M, respectively. In the case of UV/Nano-TiO{sub 2} process, we have studied the influence of the basic photocatalytic parameters such as the irradiation time, pH of the solution and amount of TiO{sub 2} nanoparticles on the photocatalytic decolorization efficiency of AB9. Accordingly, it could be stated that the complete removal of color, after selecting desired operational parameters could be achieved in a relatively short time, about 25 min. Our results also revealed that the most effective decomposition of AB9 was observed with 150 mg/l of TiO{sub 2} nanoparticles in acidic condition. The effect of operational parameters including current density, initial pH and time of electrolysis were studied in electrocoagulation process. The results indicated that for a solution of 20 mg/l AB9, almost 98% color were removed, when the pH was about 6, the time of electrolysis was 8 min and the current density was approximately 25 A/m{sup 2} in electrocoagulation process.

Plant Proteinase Inhibitor BbCI Modulates Lung Inflammatory Responses and Mechanic and Remodeling Alterations Induced by Elastase in Mice

OpenAIRE

Almeida-Reis, Rafael; Theodoro-Junior, Osmar A.; Oliveira, Bruno T. M.; Oliva, Leandro V.; Toledo-Arruda, Alessandra C.; Bonturi, Camila R.; Brito, Marlon V.; Lopes, Fernanda D. T. Q. S.; Prado, Carla M.; Florencio, Ariana C.; Martins, Mílton A.; Owen, Caroline A.; Leick, Edna A.; Oliva, Maria L. V.; Tibério, Iolanda F. L. C.

2017-01-01

Background. Proteinases play a key role in emphysema. Bauhinia bauhinioides cruzipain inhibitor (BbCI) is a serine-cysteine proteinase inhibitor. We evaluated BbCI treatment in elastase-induced pulmonary alterations. Methods.??C57BL/6 mice received intratracheal elastase (ELA group) or saline (SAL group). One group of mice was treated with BbCI (days 1, 15, and 21 after elastase instillation, ELABC group). Controls received saline and BbCI (SALBC group). After 28 days, we evaluated respirator...

SeDiCI: Servicio de Difusión de la Creación Intelectual

Directory of Open Access Journals (Sweden)

Marisa R. de Giusti

2008-07-01

Full Text Available Presenta el Servicio de Difusión de la Creación Intelectual (SeDiCI de la Universidad Nacional de La Plata (UNLP, Argentina, desde el punto de vista de los objetivos que condujeron a la UNLP a su creación. Se describen en detalle las etapas por las que se atravesó para poner en marcha este repositorio institucional y especialmente las facilidades que provee el software Celsius-DL desarrollado en la UNLP que soporta el Portal de SeDiCI.

Przestrzenne nierówności oferty edukacyjnej w zdecentralizowanym systemie oświaty. Przypadek Polski

Directory of Open Access Journals (Sweden)

Mikołaj Herbst

2014-03-01

Full Text Available Decentralizacja edukacji, podobnie jak decentralizacja wszelkich usług publicznych, wiąże się z ryzykiem zwiększenia nierówności między jednostkami samorządu terytorialnego w zakresie ponoszonych nakładów i jakości usług. W większości państw próbuje się temu zaradzić poprzez ustanowienie krajowych standardów usług edukacyjnych oraz redystrybucję środków finansowych, która pozwala zneutralizować wpływ terytorialnych zróżnicowań bazy podatkowej. Niniejsze opracowanie poświęcone będzie analizie skutecznościowych działań w przypadku Polski. W pierwszej części, na podstawie danych panelowych na poziomie gmin, pokazujemy, że mimo różnych instrumentów wyrównawczych stosowanych przez rząd centralny, lokalna baza podatkowa w znaczącym stopniu wpływa na wysokość nakładów przeznaczanych na edukację gimnazjalną. W części drugiej porównujemy liczbę i charakter przedmiotowy godzin lekcyjnych w gimnazjach położonych w najbiedniejszych i najbogatszych gminach. Wedle naszych ustaleń czas nauczania dla uczniów z najbiedniejszych i najbogatszych środowisk nie jest istotnie różny. Nie występują także znaczące różnice wysokości wynagrodzeń nauczycieli. Biedne i bogate gminy różnią się natomiast zakresem indywidualnego wsparcia dla uczniów.

Co jest stawką mobilności pracy? Granice, migracje, współczesny kapitalizm

Directory of Open Access Journals (Sweden)

Sandro Mezzadra

2016-09-01

Full Text Available Prezentowany tekst rozpoczyna się od krótkiego omówienia kilku wpływowych badań na temat mobilności pracy w ramach historycznego i współczesnego kapitalizmu. Później, opierając się na ustaleniach z ostatniej książki autora, Border as Method, or, the Multiplication of Labour (napisanej razem z Brettem Neilsonem, przechodzi do namysłu nad znaczeniem upowszechnienia się granic w epoce globalizacji z perspektywy „późnego” kapitalizmu. W ostatniej części autor skupia się na podmiotowym wymiarze polityki migracji, dostarczając w tym kontekście wielu przykładów z różnych części świata (w tym z regionu Pacyfiku.

Filosofia da ciência como ferramenta microeconômica

OpenAIRE

Fabio Barbieri

2006-01-01

A teoria neoclássica pressupõe conhecimento perfeito. A crítica hayekiana a essa teoria, por sua vez, afirma que esse conhecimento é resultado do processo competitivo e, portanto, não pode ser considerado como dado. O "Problema de Hayek" investiga sob que condições o conhecimento do agente se aproxima dos reais fundamentos de uma economia. A fim de solucionar o "Problema de Hayek", o nosso artigo utiliza algumas idéias da literatura de metodologia da Ciência, conhecida como teoria do "crescim...

Physical and chemical properties of selected soils from the surroundings of the Magura National Park (southern Poland / Właściwości fizykochemiczne i chemiczne wybranych gleb z otoczenia Magurskiego Parku Narodowego

Directory of Open Access Journals (Sweden)

Szewczyk Adam

2015-03-01

Full Text Available Celem pracy było określenie podstawowych właściwości fizykochemicznych i chemicznych sześciu profili glebowych zlokalizowanych w otoczeniu Magurskiego Parku Narodowego. Przy wyborze miejsc odkrywek kierowano się rodzajem użytkowania rolniczego oraz rzeźbą terenu. W wyniku badañ zgodnie z SGP5 zidentyfikowano następujące typy lub podtypy gleb: glejowa typowa GWt (Eutric Gleysols, brunatna dystroficzna typowa BDt (Dystric Cambisols, brunatna eutroficzna wyługowana BEwy (Eutric Cambisols, gleba antropogeniczna, kulturoziemna regulówkowa AKre (Eutric Cambisols Aric oraz gleba płowa próchniczna PWpr (Gleyic Luvisols. Analizowane gleby charakteryzowały się uziarnieniem glin pylastych lub utworów pyłowych. Były zazwyczaj silnie zakwaszone, o czym świadczyło niskie pH (w 1M KCl wartości zawierały się w przedziale od 3,8 do 5,8, wysokie wartości kwasowości hydrolitycznej (od 0,8 do 10,0 cmol(+·kg-1 i wymiennej (od 0,05 do 4,05 cmol(+·kg-1 oraz znacząca zawartość glinu wymiennego (od 0 do 3,96 cmol(+·kg-1. Zawartość węgla organicznego w badanych profilach nie przekraczała (za wyjątkiem profilu 1 30 g·kg-1 i wraz z głębokością malała do kilku g·kg-1 w poziomach skały macierzystej. Gleby te cechowały się niezbyt wysoką zawartością azotu całkowitego (od 0,30 do 9,39 g·kg-1 oraz niską zawartością fosforu przyswajalnego (od 3,5 do 90,3 mg P2O5·kg-1. Natomiast zawartość przyswajalnego potasu (od 82 do 570 mg K2O·kg-1 oraz magnezu (od 33 do 412 mg Mg·kg-1 pozwalała zakwalifikować badane gleby do kategorii średnio bądź wysoko zasobnych. Najwyższe wartości pierwiastków biogennych wykrywano w poziomach powierzchniowych. Badane gleby charakteryzowały się wysoką, całkowitą pojemnością sorpcyjną (T - od 7,0 do 63,4 cmol(+·kg-1. Suma kationów o charakterze zasadowym (S przyjmowała wartości od 3,0 do 61,2 cmol(+·kg-1, co skutkowało wysokim wysyceniem kompleksu sorpcyjnego zasadami (V

Ocena sprawności funkcjonalnej chorych na reumatoidalne zapalenie stawów na podstawie funkcjonalnego testu z wystandaryzowanym wyposażeniem

Directory of Open Access Journals (Sweden)

Grażyna Bączyk

2011-02-01

Full Text Available Reumatoidalne zapalenie stawów (RZS jest przewlekle postępującymprocesem zapalnym błony maziowej, doprowadzającym doniszczenia tkanek stawowych i okołostawowych, w wyniku czegodochodzi do zniekształceń i upośledzenia funkcji stawów, co w konsekwencjiprowadzi do trwałego kalectwa. Celem badań była ocenasprawności funkcjonalnej chorych na RZS. Materiały i metody: Grupę badaną stanowiło 120 chorych na reumatoidalnezapalenie stawów leczonych w poradni reumatologicznejw Poznaniu. Kobiety stanowiły 75% badanych. Średnia wiekubadanych to 52,15 roku (SD 12,73. Średni czas trwania chorobywynosił 13,47 roku, (SD 8,62 (tab. I.Objawy ze strony układu kostno-stawowego oceniano wg następującychzasad: czas trwania sztywności porannej, natężenie bólu wgskali VAS, bolesność uciskowa stawów z wykorzystaniem RitchieArticular Index, siła mięśniowa ręki na podstawie siły chwytu. Dooceny sprawności funkcjonalnej chorych wykorzystano funkcjonalnytest z wystandaryzowanym wyposażeniem (tab. II. Wyniki: Około 60% kobiet i 40% mężczyzn nie było zdolnych dowykonania takiego zadania, jak otwieranie słoika. Wykonanie większościzadań wymagało od badanych zastosowania pewnego rodzajupomocy technicznej albo wykonanie danej czynności odbywało siępowoli czy też z pomocą drugiej osoby (tab. III. Wnioski: Złe wyniki oceny funkcjonowania chorych na reumatoidalnezapalenie stawów, niezależnie od płci, świadczą o ograniczeniumożliwości wykonywania podstawowych aktywności życiowych.Wiązało się to z bólem stawów, czasem trwania objawu sztywnościporannej oraz słabą siłą mięśniową rąk.

Multilevel evaluation of 'China Healthy Lifestyles for All', a nationwide initiative to promote lower intakes of salt and edible oil.

Science.gov (United States)

Zhang, Juan; Astell-Burt, Thomas; Seo, Dong-Chul; Feng, Xiaoqi; Kong, Lingzhi; Zhao, Wenhua; Li, Nicole; Li, Yuan; Yu, Shicheng; Feng, Guoshuang; Ren, Duofu; Lv, Yuebin; Wang, Jinglei; Shi, Xiaoming; Liang, Xiaofeng; Chen, Chunming

2014-10-01

To evaluate the impact of 'China Healthy Lifestyle for All' on levels of knowledge, taste and intentions to modify future consumption of salt and edible oil. Between May and August 2012, a face-to-face survey carried out in all 31 provinces, autonomous regions, and municipalities in mainland China, achieved a 98.1% response. Intention-To-Treat analysis via multilevel logistic regression was used to examine differences in outcomes between 31,396 non-institutionalised individuals aged > 18 years from 31 'intervention' (i.e. participating) and 26 'control' (i.e. non-participating) counties respectively. Adjusting for socioeconomic confounders, participants in 'intervention' counties were more likely to know the limit of salt (Odds Ratio 3.14, 95% Confidence Interval (95% CI) 1.98, 4.96) and oil consumption (3.67, 95% CI 2.31, 5.82), and were more intent to modify their consumption (salt 1.98, 95% CI 1.41, 2.76; oil OR 1.99, 95% CI 1.41, 2.81) and to report a change in taste (salt 1.90, 95% CI 1.31, 2.75; oil 2.07, 95% CI 1.38, 3.10). 'Intervention' effects were consistent regardless of income or education, but women and older participants benefited disproportionately. Outcomes were 2.8 and 4.7 times more likely among those with better recall. Place-based health promotion interventions have an important role to play in addressing non-communicable disease in China. Copyright © 2014 Elsevier Inc. All rights reserved.

I-Xe dating of aqueous alteration in the CI chondrite Orgueil: I. Magnetite and ferromagnetic separates

Science.gov (United States)

Pravdivtseva, O.; Krot, A. N.; Hohenberg, C. M.

2018-04-01

The I-Xe system was studied in a ferromagnetic sample separated from the Orgueil CI carbonaceous chondrite with a hand-held magnet and in two magnetite samples, one chemically separated before and the other one after neutron irradiation. This work was done in order to investigate the effects of chemical separation by LiCl and NaOH on the I-Xe system in magnetite. Our test demonstrated that the chemical separation of magnetite before irradiation using either LiCl or NaOH, or both, does not contaminate the sample with iodine and thus cannot lead to erroneous I-Xe ages due to introduction of uncorrelated 128∗Xe. The I-Xe ages of two Orgueil magnetite samples are mutually consistent within experimental uncertainties and, when normalized to an absolute time scale with the reevaluated Shallowater aubrite standard, place the onset of aqueous alteration on the CI parent body at 4564.3 ± 0.3 Ma, 2.9 ± 0.3 Ma after formation of the CV Ca-AI-rich inclusions (CAIs). The I-Xe age of the ferromagnetic Orgueil separate is 3.4 Ma younger, corresponding to a closure of the I-Xe system at 4560.9 ± 0.2 Ma. These and previously published I-Xe data for Orgueil (Hohenberg et al., 2000) indicate that aqueous alteration on the CI parent body lasted for at least 5 Ma. Although the two magnetite samples gave indistinguishable I-Xe ages, their temperature release profiles differed. One of the two Orgueil magnetites released less radiogenic Xe than the other, 80% of it corresponding to the low-temperature peak of the release profile, compared to only 6% in case of the second Orgueil magnetite sample. This could be due to the difference in iodine trapping efficiencies for magnetite grains of different morphologies. Alternatively, the magnetite grains with the lower radiogenic Xe concentrations may have formed at a later stage of alteration when iodine in an aqueous solution was depleted.

Używki w ciąży – kofeina = Stimulants in pregnancy – caffeine

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Agnieszka Konstancja Pawłowska-Muc

2015-06-01

3 Independent Obstetric Skills Workshop, Medical University of Lublin, ul. Staszica 4/6   Adres do korespondencji: mgr piel. Agnieszka Konstancja Pawłowska-Muc Ośrodek Kształcenia Podyplomowego Pielęgniarek i Położnych Radomski Szpital Specjalistyczny im. dr Tytusa Chałubińskiego w Radomiu, ul. Lekarska 4 tel. 48  3615616; fax: 48 3615437 e-mail: agmich@vp.pl   Używki w ciąży - kofeina Streszczenie Wprowadzenie. Kofeina należy do substancji psychoaktywnych, ogólnodostępnych i najbardziej rozpowszechnionych na całym świecie. Jej wpływ na zdrowie kobiet, przebieg ciąży i rozwój płodu jest od lat przedmiotem wielu dyskusji, sporów i dociekań naukowych. Cel pracy. Przegląd piśmiennictwa na temat wpływu działania kofeiny na organizm kobiety oraz skutków jej spożywania w okresie ciąży i laktacji. Skrócony opis stanu wiedzy. Działanie kofeiny na organizm kobiety oraz jej wpływ na przebieg ciąży i zdrowie dziecka nie zostały dotychczas w pełni poznane. Znajduje się ona w wielu produktach, a to sprawia, że jej całkowite, dzienne spożycie jest trudne do oceny.             Podsumowanie. Z przeglądu piśmiennictwa wynika, że duży odsetek kobiet ciężarnych ma zwyczaj codziennego picia herbaty i/lub kawy z kofeiną. Zakres embriotoksycznego działania tej substancji zależy od jej dawki, częstości spożywania oraz stanu zdrowia kobiety ciężarnej. Stanowiska  autorów, co do stosowania napojów zawierających kofeinę w tym czasie, a także ich skutków, są podzielone. Większość jednak podziela pogląd, iż w ciąży i w okresie laktacji należy ograniczyć, a najlepiej zaniechać, spożywanie takich napojów. Zasadne jest zatem, aby działania promujące i wspierające zdrowy styl życia kobiet w wieku rozrodczym dotyczyły, między innymi, tej kwestii. Słowa kluczowe: kofeina, ciężarna, zdrowie, ciąża, płód.   Stimulants in pregnancy - caffeine Summary Introduction. Caffeine belongs to the group of

A metafísica na ciência moderna: uma discussão heideggeriana

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Flávio Oliveira Silva

2015-07-01

Full Text Available O artigo apresenta duas teses de Heidegger: a interpretação da Crítica da Razão Pura como metafísica e a afirmação da permanência da metafísica na ciência moderna. Em seguida analisa as objeções que Loparic apresenta a essas teses no artigo A metafísica e o processo de objetificação,para enfim argumentar que suas contestações não se sustentam. Loparic afirma que  a Crítica da Razão Pura não se destina a investigar a quididade dos entes, mas as condições nas quais os juízos sintéticos a priori podem ser verdadeiros ou falsos, de modo que o problema tratado por Kant não seria ontológico, mas semântico. Loparic afirma ainda que a ciência moderna deixou o quadro ontológico da metafísica aristotélica, na medida em que não mais se destina a estudar os entes como tais, isto é, como uma coisa em si, mas tão somente investigar a resposta da natureza, mediante intervenção técnica no curso dos processos naturais e, portanto não há sequer resquício da metafísica na ciência moderna. Essas objeções apresentam dificuldades na medida em que o autor se utiliza do conceito tradicional de metafísica para tratar da filosofia de Heidegger. Argumenta-se que o sentido de metafísica para Heidegger não se restringe à concepção de metafísica da tradição, de modo que, constitui um equívoco analisar as teses heideggerianas em conformidade com a leitura da tradição.  Heidegger se pauta na indicação de que Kant se ocupa das condições de possibilidade da compreensão, isto é, do Dasein, enquanto o ente que coloca a pergunta sobre o ser e é nesta dimensão que a Crítica da Razão Pura é recepcionada como metafísica. No tocante à ciência, o filósofo afirma que, mesmo a ciência moderna tendo abandonado a representação de objetos, ela não renunciou e nem poderia renunciar à necessidade de a natureza fornecer dados que se possa calcular e de continuar sendo um sistema disponível de informação, de modo

Experimental evaluation of C.I. engine performance using diesel blended with Jatropha biodiesel

Energy Technology Data Exchange (ETDEWEB)

Kumar, Sunil [Mechanical Department, R. G. P. V. Bhopal (M.P.) (India); Chaube, Alok [Mechanical Department, Jabalpur Engineering College Jabalpur (M.P.) (India); Jain, Shashi Kumar [School of Energy and Environment Management, R.G.P.V. Bhopal (India)

2012-07-01

Costlier and depleting fossil fuels are prompting researchers to use edible as well as non-edible vegetable oils as promising alternative to petro-diesel. The higher viscosity of vegetable oils leads to problem in pumping, atomization and spray characteristics. The improper mixing of vegetable oils with air leads to incomplete combustion. The best way to use vegetable oils as fuel in compression ignition (CI) engines is to convert it into biodiesel. Biodiesel is a methyl or ethyl ester of fatty acids made from vegetable oils (both edible and non-edible) and animal fat. The main feedstock for biodiesel production can be non-edible oil obtained from Jatropha curcas plant. Jatropha curcas plant can be cultivated on different terrains in India under extreme climatic conditions. Biodiesel can be used in its pure form or as a blend with petro-diesel in different proportions. It is being used in CI engines because it has properties similar to petro-diesel. The aim of this paper is to analyze suitability of petro-diesel blended with biodiesel in varying proportions in CI engines. For this purpose, a stationary single-cylinder four-stroke CI engine was tested with diesel blended with Jatropha biodiesel in 0%, 5%, 20%, 50%, 80% and 100%. Comparative measures of specific fuel consumption (SFC), brake thermal efficiency, smoke opacity, HC, CO2, CO, O2, NOX have been presented and discussed. Engine performance in terms of comparable brake thermal efficiency and SFC with lower emissions (HC, CO2, CO) was observed with B20 fuel compared to petro-diesel. Volumetric efficiency showed almost no variation for all the blends. Important observations related to noise and vibrations during testing have also been discussed.

Time course of auditory streaming: Do CI users differ from normal-hearing listeners?

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Martin eBöckmann-Barthel

2014-07-01

Full Text Available In a complex acoustical environment with multiple sound sources the auditory system uses streaming as a tool to organize the incoming sounds in one or more streams depending on the stimulus parameters. Streaming is commonly studied by alternating sequences of signals. These are often tones with different frequencies. The present study investigates stream segregation in cochlear implant (CI users, where hearing is restored by electrical stimulation of the auditory nerve. CI users listened to 30-s long sequences of alternating A and B harmonic complexes at four different fundamental frequency separations, ranging from 2 to 14 semitones. They had to indicate as promptly as possible after sequence onset, if they perceived one stream or two streams and, in addition, any changes of the percept throughout the rest of the sequence. The conventional view is that the initial percept is always that of a single stream which may after some time change to a percept of two streams. This general build-up hypothesis has recently been challenged on the basis of a new analysis of data of normal-hearing listeners which showed a build-up response only for an intermediate frequency separation. Using the same experimental paradigm and analysis, the present study found that the results of CI users agree with those of the normal-hearing listeners: (i the probability of the first decision to be a one-stream percept decreased and that of a two-stream percept increased as Δf increased, and (ii a build-up was only found for 6 semitones. Only the time elapsed before the listeners made their first decision of the percept was prolonged as compared to normal-hearing listeners. The similarity in the data of the CI user and the normal-hearing listeners indicates that the quality of stream formation is similar in these groups of listeners.

Computer-assisted CI fitting: Is the learning capacity of the intelligent agent FOX beneficial for speech understanding?

Science.gov (United States)

Meeuws, Matthias; Pascoal, David; Bermejo, Iñigo; Artaso, Miguel; De Ceulaer, Geert; Govaerts, Paul J

2017-07-01

The software application FOX ('Fitting to Outcome eXpert') is an intelligent agent to assist in the programing of cochlear implant (CI) processors. The current version utilizes a mixture of deterministic and probabilistic logic which is able to improve over time through a learning effect. This study aimed at assessing whether this learning capacity yields measurable improvements in speech understanding. A retrospective study was performed on 25 consecutive CI recipients with a median CI use experience of 10 years who came for their annual CI follow-up fitting session. All subjects were assessed by means of speech audiometry with open set monosyllables at 40, 55, 70, and 85 dB SPL in quiet with their home MAP. Other psychoacoustic tests were executed depending on the audiologist's clinical judgment. The home MAP and the corresponding test results were entered into FOX. If FOX suggested to make MAP changes, they were implemented and another speech audiometry was performed with the new MAP. FOX suggested MAP changes in 21 subjects (84%). The within-subject comparison showed a significant median improvement of 10, 3, 1, and 7% at 40, 55, 70, and 85 dB SPL, respectively. All but two subjects showed an instantaneous improvement in their mean speech audiometric score. Persons with long-term CI use, who received a FOX-assisted CI fitting at least 6 months ago, display improved speech understanding after MAP modifications, as recommended by the current version of FOX. This can be explained only by intrinsic improvements in FOX's algorithms, as they have resulted from learning. This learning is an inherent feature of artificial intelligence and it may yield measurable benefit in speech understanding even in long-term CI recipients.

Evaluation of radioiodine therapy with fixed doses of 10 and 15 mCi in patients with Graves disease

International Nuclear Information System (INIS)

Canadas, Viviane; Vilar, Lucio; Moura, Eliane; Brito, Ana; Castellar, Enio

2007-01-01

The treatment options for the hyperthyroidism of Graves' disease are antithyroid drugs, surgery and radioiodine, none of which is considered ideal, as they do not act directly on the etiopathogenesis of the disease. Radioiodine has been increasingly used as the treatment of choice because it is a safe and definitive therapy whose administration is very easy. Some authors prefer to administer higher doses in order to deliberately induce hypothyroidism, while others recommend lower doses that result in a lower incidence of hypothyroidism and a greater incidence of euthyroidism. There is no consensus for the optimal regimen of fixed doses to be used and this is the main focus of the present study, where doses of 10 and 15 mCi of 131 I were compared. Among the 164 patients analyzed, 61 (37.2%) were submitted to 10 mCi and 103 (62.8%) to 15 mCi. In the longitudinal analysis it was observed that remission of the hyperthyroidism was statistically different in the sixth month (p 131 I brought about a similar remission of the hyperthyroidism after 12 months of treatment. Moreover, the remission rate of the hyperthyroidism had no association with age, sex or previous therapy with antithyroid drugs. (author)

Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements.

Science.gov (United States)

Lundby, Alicia; Mutoh, Hiroki; Dimitrov, Dimitar; Akemann, Walther; Knöpfel, Thomas

2008-06-25

Ci-VSP contains a voltage-sensing domain (VSD) homologous to that of voltage-gated potassium channels. Using charge displacement ('gating' current) measurements we show that voltage-sensing movements of this VSD can occur within 1 ms in mammalian membranes. Our analysis lead to development of a genetically encodable fluorescent protein voltage sensor (VSFP) in which the fast, voltage-dependent conformational changes of the Ci-VSP voltage sensor are transduced to similarly fast fluorescence read-outs.

Jaką teorią jest Marksowska teoria wartości opartej na pracy?

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Krzysztof Nowak-Posadzy

2015-12-01

Full Text Available Tak zwana teoria wartości opartej na pracy (odtąd LTV, niegdyś powód do dumy całego środowiska marksistowskiego, stawała się z upływem lat przedmiotem jego zakłopotania. Jej odrzucenie w ramach tradycji lewicowej, zarówno przez część filozofów, jak i ekonomistów, wpisuje się w szersze zjawisko zwane „kryzysem marksizmu”. Wówczas to filozoficzna część środowiska marksistowskiego, chcąc uwolnić marksizm od wad „ekonomizmu”, odcięła go także od zalet mogących płynąć z przyjęcia perspektywy ekonomii teoretycznej. Natomiast część ekonomiczna przywołanego środowiska, chcąc uwolnić ekonomię marksistowską od niedociągnięć tkwiących w LTV, odcięła ją także od szczególnego statusu przypisywanego w tej tradycji intelektualnej pojęciu pracy. Chociaż uniewinniono później LTV od zarzutu o domniemaną logiczną sprzeczność, to jedynie po to, aby skazać ją następnie na zapomnienie za jej rzekomą zbyteczność. W niniejszym artykule omówiona zostanie specyfika Marksowskiej wersji LTV. We wstępie podane zostaną cztery jakościowe założenia, które, zdaniem autora, przesądzają o charakterze Marksowskiej wersji LTV, W pierwszej części zarysowane zostanie miejsce LTV w historii myśli ekonomicznej. Druga część dotyczyć będzie losów Marksowskiej wersji LTV w ramach samej tradycji marksistowskiej. W trzeciej części omówiony zostanie problem wartości i jej pomiaru. Czwarta część zostanie poświęcona analizie problemu pracy i wyboru jednostki jej pomiaru, a także próbie zrekonstruowania Marksowskiej teorii reprodukcji pracowników za pomocą pracy. W części piątej podjęta zostanie kwestia tego, jak interpretuje się współcześnie status metodologiczny marksowskiej wersji LTV. Artykuł kończy podsumowanie.

Aulas de ciências para surdos: estudos sobre a produção do discurso de intérpretes de LIBRAS e professores de ciências

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Walquíria Dutra de Oliveira

2015-06-01

Full Text Available O bilinguismo na educação de surdos pressupõe a língua de sinais como primeira língua do surdo e, com a inclusão escolar, os alunos surdos foram inseridos em instituições regulares de ensino, implicando uma nova estrutura da sala de aula. O ensino de ciências para surdos é um desafio, pois o aluno surdo utiliza uma língua diferente da do professor, e necessita de um intérprete de LIBRAS para ter acesso ao corpo de conhecimentos mediados por ele. A investigação objetivou analisar a produção de narrativas (um gênero do discurso de professores e intérpretes de LIBRAS sobre a aula de ciências para surdos. As narrativas foram produzidas no “diário de aula”, e foram analisadas pela técnica de análise de conteúdo. Nossos resultados apontam que o bilinguismo ainda não permeia a sala de aula inclusiva, e que a barreira linguística é a maior dificuldade encontrada no aprendizado dos conhecimentos científicos pelos alunos surdos.

 Znaczenie dorobku naukowego Profesor Elżbiety Burzym dla rozwoju nauki i praktyki rachunkowości w Polsce

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Irena Sobańska

2014-04-01

Full Text Available  Celem artykułu jest przypomnienie znaczenia dorobku naukowego Profesor Elżbiety Burzym dla rozwo-ju teorii rachunkowości, badań naukowych w tej dyscyplinie oraz praktyki rachunkowości w Polsce. Przedmiotem artykułu są definicje, tezy, poglądy i koncepcje teoretyczne systemu rachunkowości oraz systemu rachunku kosztów formułowane przez Profesor Burzym, które stanowią znaczący wkład w rozwój teorii rachunkowości w Polsce. W artykule objaśniono na przykładzie z literatury skutki roz-wiązywania problemów rachunkowości z perspektywy proceduralno-formalnej, a nie merytorycznej, która dominowała w opracowaniach naukowych Profesor Burzym.

Ocena sprawności działania państwa w odniesieniu do skali wydatków publicznych

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Marta Postuła

2013-06-01

Full Text Available Cel: Celem artykułu jest potwierdzenie tezy, że skala wydatkowania środków publicznych nie wpływa na sprawność działania państwa, która w większej skali jest uzależniona od efektywności ich wydatkowania.Metodologia: Autorka opiera się na przeglądzie literatury, przeprowadzonym na podstawie baz artykułów naukowych, oraz na analizie konkretnych rozwiązań obowiązujących w Unii Europejskiej i krajach członkowskich OECD, odnoszących się do konsolidacji funduszy w kontekście sprawności działania państwa.Oryginalność: Na bazie analizy przeprowadzonej w artykule autorka dowodzi, że optymalna polityka fiskalna powinna wykorzystywać dobrze dobrane narzędzia pozwalające na osiągnięcie maksymalnie dobrego sposobu gospodarowania środkami publicznymi w danym otoczeniu zewnętrznym i wewnętrznym, w jakim znajduje się dana gospodarka. Czynnikiem decydującym o sprawności państwa (pomijając czynniki pozafinansowe nie są absolutne i względne rozmiary wydatków publicznych. Poziom sprawności jest uzależniony od struktury tych wydatków oraz procedur związanych zarówno z procesem planowania, realizacji, ewidencji i sprawozdawczości dotyczącej wydatków publicznych, jak i z poziomem systemu oceny efektywności i skuteczności.

Escrevendo em aulas de ciências Writing in science classes

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Carla Marques Alvarenga de Oliveira

2005-12-01

Full Text Available Neste artigo, apresentamos uma análise dos registros escritos dos alunos do 3° ano do Ensino Fundamental nas aulas de Ciências, em que a professora utilizou as atividades de conhecimento físico, criadas pelo Laboratório de Pesquisa e Ensino de Física da Faculdade de Educação da Universidade de São Paulo. Os registros analisados foram coletados na Escola de Aplicação da Feusp, no ano de 2001, durante o acompanhamento de três aulas de Ciências: o problema do submarino, o problema do barquinho e o problema da pressão. O artigo procura mostrar um panorama de como aparecem os registros realizados pelos alunos, após uma aula de Ciências em que eles são levados a resolver situações problemáticas por meio da experimentação, argumentar e escrever sobre os fenômenos físicos. Durante a análise, levou-se em consideração os tipos de textos que os alunos escrevem, o uso da primeira pessoa, o uso de verbos de ação, o respeito à ordem cronológica dos eventos e quais os tipos de explicações os alunos atribuem aos fenômenos trabalhados.This article analyzed the written records of Third Grade students of Elementary School at Escola de Aplicação, Universidade de São Paulo, gathered during the Science classes of the 2001 school year, in which activities about physical understanding were used. Created by the Laboratory of Research and Teaching of Physics - LAPEF, of the College of Education of USP, the activities "The Problem of the Submarine", "The Problem of the Little Boat" and "The Problem of the Pressure" required the students to solve problematic situations through experimentation, developing arguments and write about the phenomena. The study developed a framework of how the records are presented by the students, considering the types of texts they produce, the use of the first person, the use of verbs of action, the respect of the chronological order of events and the types of explanations the students give for the

Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements.

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Alicia Lundby

2008-06-01

Full Text Available Ci-VSP contains a voltage-sensing domain (VSD homologous to that of voltage-gated potassium channels. Using charge displacement ('gating' current measurements we show that voltage-sensing movements of this VSD can occur within 1 ms in mammalian membranes. Our analysis lead to development of a genetically encodable fluorescent protein voltage sensor (VSFP in which the fast, voltage-dependent conformational changes of the Ci-VSP voltage sensor are transduced to similarly fast fluorescence read-outs.

Cluster expansion of the wavefunction. Calculation of electron correlations in ground and excited states by SAC and SAC CI theories

International Nuclear Information System (INIS)

Nakatsuji, H.

1979-01-01

The SAC and SAC CI theories are formulated for actual calculations of singlet ground states and their excited states of arbitrary spin multiplicity. Approximations are considered for the variational methods since time-consuming terms are involved. The results of test calculations for singlet states have shown, with much smaller numbers of variables (sizes of the matrices involved), excellent agreement with the full CI and close-to-full CI results. This shows the utility of the SAC theory for ground states and especially of the SAC CI theory for excited states, since the slow convergence of the CI theory is much more critical for excited states than for ground states. (Auth.)

Problem wolności w Internecie / The problem of freedom in Internet

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Iwona Gleisner

2013-07-01

Full Text Available Artykuł jest próbą odpowiedzi na pytanie o granice wolności w Internecie. Dyskusje ten temat, toczące się na całym świecie od dawna, nie dały dotąd zadowalającej odpowiedzi. W ostatnich latach przybiera na sile spór pomiędzy zwolennikami pełnej swobody, a stronnikami prawnego ograniczania korzystania z zasobów globalnej sieci. Autorka przytacza argumenty obu stron konfliktu, zwracając uwagę na potrzebę znalezienia równowagi prawnej pomiędzy interesami twórców, a potrzebami odbiorców. Porusza ponadto istotne zagadnienie moralnej odpowiedzialności autorów za zamieszczane w Internecie treści.English abstractThis paper attempts to find an answer to the question about freedom in Internet. This issue has been discussed all over the world for long, however no satisfactory answer has yet been found. Recently, the dispute between the supporters of the full freedom and the ones voting for limiting the resources of the global network with legal means has been becoming more fierce. The author quotes arguments of both parties to the conflict, drawing attention to the need of finding a legal balance between the interests of the artists and the needs of the consumers. She also tackles with an important issue of moral responsibility of the authors for the contents placed in Internet. Normal 0 21 false false false PL X-NONE X-NONE

Narrativas históricas: gravidade, sistemas de mundo e natureza da ciência

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Juliana M. Hidalgo F. Drummond

2015-04-01

Full Text Available http://dx.doi.org/10.5007/2175-7941.2015v32n1p99 De acordo com o entendimento de que o ensinar ciência e o ensinar sobre a ciência não devem estar dissociados, apresenta-se um conjunto de narrativas históricas para utilização no Ensino Médio, tecendo considerações sobre os recortes históricos procedidos e as escolhas implementadas em sua elaboração. Procura-se chamar a atenção para as potencialidades, possibilidades e limitações das narrativas. Esses pontos remetem explicitamente a reflexões relacionadas a uma utilização flexível, tendo em vista particularidades dos contextos educacionais.

Dolegliwości bólowe pleców u kobiet w ciąży – doniesienie wstępne = The back pain in pregnant women – a preliminary report

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Anna Bogusława Pilewska-Kozak

2017-02-01

Pilewska–Kozak Anna Bogusława1, Stadnicka Grażyna2, Łepecka–Klusek Celina1, Dobrowolska Beata3, Pałucka Klaudia1, Pawłowska-Muc Agnieszka Konstancja4, Kozak Łukasz Adam5       1 Katedra i Klinika Ginekologii i Endokrynologii Ginekologicznej Wydział Nauk o Zdrowiu Uniwersytet Medyczny w Lublinie 2 Zakład Podstaw Położnictwa Wydział Nauk o Zdrowiu Uniwersytet Medyczny w Lublinie 3 Katedra Rozwoju Pielęgniarstwa Wydział Nauk o Zdrowiu Uniwersytet Medyczny w Lublinie 4  Powiatowe Centrum Medyczne w Grójcu Sp. z o. o 5 Oddział Urazowo – Ortopedyczny z Chirurgią Kręgosłupa Samodzielnego Publicznego Szpitala Wojewódzkiego w Chełmie       Adres do korespondencji: Dr n. med. Anna B. Pilewska-Kozak ul. Aleje Racławickie 23, 20-049 Lublin e-mail: apilewska@poczta.wp.pl tel. 26 118 32 86       Streszczenie   Badaniami objęto 80 kobiet między25. a36. tygodniem ciąży, uczestniczących w zajęciach szkół rodzenia. Wiek kobiet wahał się w granicach od 19 do 42 lat (średnia wieku wynosiła 27,8 ± 4 lata. Wykorzystano kwestionariusz ankiety, własnej konstrukcji oraz wizualną analogową skalę VAS (0 – brak bólu do 10- ból nie do wytrzymania do oceny bólu kręgosłupa. Celem pracy było sprawdzenie czy u kobiet w ciąży występuje ból kręgosłupa oraz w jakich sytuacjach się nasila. Na podstawie przeprowadzonych badań stwierdzono, że większości kobiet odczuwała ból kręgosłupa w odcinku lędźwiowym. Wśród sytuacji nasilających dolegliwość najwięcej wymieniało pozycję stojącą, co trzecia siedzącą, a co piąta chodzenie.   Słowa kluczowe: ból kręgosłupa, ciąża     Summary             The study involved 80 women between the 25th and 36th week of pregnancy attending antenatal classes. The age of women ranged from 19 to 42 years old (the age median was 27,8 ± 4 years. The questionnaire of our own design and the Visual Analogue Scale VAS (0 – no pain to 10 - unbearable pain were used to

Martwica kości szczęk związana ze stosowaniem bifosfonianów. Opis przypadków

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Wojciech Leśniak

2013-06-01

Full Text Available Bifosfoniany należą do silnych inhibitorów osteoklastów. Znajdują szerokie zastosowanie w leczeniu chorób przebiegających ze wzmożoną resorpcją kości: osteoporozy, choroby Pageta i osteogenesis imperfecta. Leki te zmniejszają adhezję komórek nowotworowych do kości, ograniczają osteolizę wywołaną nowotworem i hiper‑ kalcemię. Zmniejszają dolegliwości bólowe w szpiczaku mnogim i w przerzutach do kości. Powszechnie panu‑ jące przekonanie o bezpieczeństwie spowodowało rozszerzenie wskazań do ich stosowania. Pacjenci onkolo‑ giczni przyjmujący bifosfoniany dożylnie, w wysokich dawkach są bardziej narażeni na działania niepożądane terapii niż pacjenci przyjmujący je doustnie. Jednym z najpoważniejszych powikłań jest martwica kości szczęk. W 2003 roku opisano po raz pierwszy związek pomiędzy terapią bifosfonianami a martwicą kości szczęk. W piśmiennictwie znajdujemy coraz więcej przykładów tego działania niepożądanego, także po stosowaniu leków doustnie. Mogą pojawiać się ból, obrzęk, owrzodzenie, odsłonięcie kości, przetoki, złamania patologiczne, uciążliwe dla pacjenta i obniżające jakość życia. Leczenie martwicy kości szczęk jest trudne i rzadko przynosi spodziewany efekt. Główną rolę odgrywa leczenie zachowawcze i redukcja objawów. Odstawienie bifosfonia‑ nów nie ma bezpośredniego wpływu na przebieg martwicy kości szczęk, ze względu na kumulację leku w kości. Istotne jest przygotowanie pacjenta przed rozpoczęciem podawania bifosfonianów, wymagające stałej współ‑ pracy pomiędzy lekarzami onkologami, ortopedami i chirurgami szczękowo-twarzowymi. Higiena jamy ustnej i leczenie chorób współistniejących stanowi ważny element postępowania. Celem pracy jest przedstawienie trzech przypadków martwicy kości szczęk u pacjentów poddanych leczeniu bifosfonianami.

Badania wartości ekonomicznej usług biblioteczno-informacyjnych i ich wpływu na otoczenie

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Ewa Głowacka

2011-01-01

Full Text Available Biblioteki pełnią różnorodne funkcje we współczesnym otoczeniu społecznym. Uczestniczą w tworzeniu kapitału intelektualnego i społecznego, wpływają na wzrost korzyści ekonomicznych użytkowników i całego społeczeństwa. W artykule omówiono główne podejścia i metody badawcze w zakresie oceny korzyści ekonomicznych płynących z funkcjonowania bibliotek. Skupiono się na metodzie analizy kosztów w stosunku do korzyści (ang. CBA – cost-benefit analysis, metodzie analizy warunkowej (ang. CVM – contigent valuation method, określaniu wartości dodanej dla użytkownika (ang. consumer surplus method i metodologii oceny stopy wzrostu z inwestycji (ang. ROI – return of investment. Przeanalizowano również różne projekty badań prowadzone na świecie w tym zakresie.

Bilans w warunkach utraty kontynuacji działalności– zasada ostrożności czy treść ekonomiczna

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Ewa Walińska

2009-10-01

Full Text Available Przedmiotem rozważań w niniejszym artykule są obecnie obowiązujące zasady sporządzania bilansu przedsiębiorstwa, które straciło zdolność do kontynuacji działalności z powodu postępowania upadłościowego. Bilans likwidacyjny rozpoczyna ostatni cykl życia przedsiębiorstwa – zakończenie jego działalności. W tym okresie zmieniają się cele działalności gospodarczej: jedynym celem staje się sprzedaż jego majątku. Brak zasady kontynuacji działalności przedsiębiorstwa upoważnia, zdaniem autorów, do odstępstw od pewnych zasad rachunkowości, głównie ostrożności, na rzecz zasady treści ekonomicznej. Takie odstępstwo realizuje zapisaną w prawie bilansowym koncepcję true and fair. W artykule postuluje się przyjęcie do wyceny majątku w bilansie likwidacyjnym wartości zbywczej niezależnie od tego, czy jest ona wyższa, czy niższa od jego wartości księgowej.

Podstawowe zasady postępowania w przebiegu chorób układu pokarmowego u kobiet w ciąży

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Ewa Tylec-Osóbka

2012-12-01

Full Text Available Chociaż ciąża jest stanem fizjologicznym, to jednak kobiety ciężarne często wymagają diagnostyki i leczenia z powodu poważnych zaburzeń ze strony przewodu pokarmowego. Zwykle są one najczęściej zgłaszanymi dolegliwościami klinicznymi w przebiegu ciąży. U części kobiet pojawiają się zaburzenia specyficzne dla ciąży. Inne ciężarne, z przewlekłymi chorobami przewodu pokarmowego, wymagają specjalnego postępowania w tym okresie. Zrozumienie przebiegu i chorobowości różnorodnych zaburzeń przewodu pokarmowego jest niezbędne, by zoptymalizować opiekę nad tymi pacjentkami. Ciąża ma niewielki wpływ na wydzielanie i wchłanianie, ale wpływa istotnie na motorykę przewodu pokarmowego. Te zaburzenia motoryki są związane z podwyższonym stężeniem żeńskich hormonów płciowych. Dodatkowo powiększająca się macica przemieszcza jelita, co jest przyczyną powszechnych dolegliwości, jakimi są zaparcia. Wiedza na temat mechanizmów adaptacyj‑ nych przewodu pokarmowego w czasie ciąży umożliwia prawidłową interpretację testów laboratoryjnych i badań obrazowych u ciężarnych. Rzadko konieczne jest wykonywanie badań endoskopowych w ciąży. Poten‑ cjalne ryzyko wynikające z endoskopii to niedotlenienie płodu powodowane lekami sedatywnymi oraz ekspo‑ zycja na promieniowanie rentgenowskie. Nie stwierdzono, by badania endoskopowe wywoływały wcześniejsze porody, a obserwacje potwierdzają, że endoskopia w czasie ciąży jest generalnie bezpieczna, przy zachowaniu określonych standardów. Badania powinno się wykonywać w przypadku mocnych wskazań, jeśli to możliwe – w drugim trymestrze ciąży. Procedury najlepiej wykonywać bez sedacji lub z użyciem najmniejszych dawek leków, minimalizując czas ekspozycji na fluoroskopię, optymalnie w obstawie anestezjologicznej i położniczej.

Radioiodine therapy of differentiated thyroid cancer: radiologic impact of out-patient treatment with 100 to 150 mCi Iodine-131 activities; Radioiodoterapia do carcinoma diferenciado da tireoide: impacto radiologico da liberacao hospitalar de pacientes com atividades entre 100 e 150 mCi de iodo-131

Energy Technology Data Exchange (ETDEWEB)

Sapienza, Marcelo Tatit; Willegaignon, Jose; Ono, Carla Rachel; Watanabe, Tomoco; Guimaraes, Maria Ines Calil Cury; Buchpiguel, Carlos Alberto [Universidade de Sao Paulo (USP), SP (Brazil). Faculdade de Medicina. Servico de Medicina Nuclear; Gutterres, Ricardo Fraga; Marechal, Maria Helena da Hora [Comissao Nacional de Energia Nuclear (CNEN), Rio de Janeiro, RJ (Brazil)

2009-07-01

Purpose: To evaluate exposure and dosimetry to family members and environment due to outpatient radioiodine therapy of differentiated thyroid carcinoma. Methods: Twenty patients were treated with 100-150 mCi of iodine-131 on an out-patient basis. Family members dosimetry (n = 27) and potential doses inside the house were measured with thermoluminescent dosimeters. Surface contamination and radioactive wastes were also monitored. Results: Less than 1.0 mSv doses were found in 26 co-habitants and 2.8 mSv in a single case (inferior to the acceptable value of 5.0 mSv/procedure). Potential doses in the houses were inferior to 0.25 mSv, excluding the patients bedroom (mean value = 0.69 mSv). Surface contamination (mean = 4.2 Bq.cm{sup -2}) were below clearance levels. Radioactive wastes generated had a volume of 2.5 liters and a total activity estimated in 90 {mu}Ci, with a calculated exposure close to the background radiation levels. Conclusions: No radiological impact was detected after iodine therapy with 100-150 mCi on an out-patient basis followed by experienced professionals. (author)

IOTA interferometer observations of the B[e] star/X-ray transient object CI Cam.

Science.gov (United States)

Thureau, N. D.; Traub, W.; Millan-Gabet, R.; Monnier, J. D.; Pedretti, E.; Berger, J.-P.; Schloerb, P.

2005-12-01

We present the results from an observing campaign on the star CI Cam carried out at the IOTA interferometer in November-December 2004 using the IONIC 3 telescope beam combiner in the H spectral band with projected baselines in the range 10-36m. CI Cam is a known B[e] star and X-ray transient source and has been intensively observed since its powerful X-ray, radio and optical outburst occurred in April 1998. Our visibility measurements put strong constraints on the nature of the source and we can rule out all existing SED models available in the literature. Our new results are in agreement with previous observations of CI Cam obtained with IOTA2 in the H and K' spectral bands in September-November 1998, indicating the infrared excess is long-lived and not directly associated with the outburst. We have explored new models that can better fit our observations. Additionally, we have measured small non-zero closure phases which are the signature of asymmetries in the brightness distribution function. Financial support for NDT is provided by the European Commission through a Marie Curie Outgoing International Fellowships MOIF-CT-2004-002990.

CI therapy is beneficial to patients which chronic low-functioning hemiparesis after stroke

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Annette eSterr

2014-10-01

Full Text Available CI therapy is effective in patients with relatively good levels of residual arm function but its applicability to patients with low functioning hemiparesis is not entirely clear. In the present study we examined the feasibility and efficacy of the CI therapy concept in patients with very limited upper arm function prior to treatment, and further tested how the length of daily shaping training and constraining the good arm affects treatment outcome. In a baseline-controlled design, 65 chronic patients were treated with 2 weeks of modified CI therapy. Patients were randomly allocated to four treatment groups receiving 90 or 180 minutes of daily shaping training applied with or without constraint respectively. Outcome was measured through the Reliable Change Index, which was calculated for parameters of motor function, health and psychological wellbeing. Follow-up data were collected at 6 and 12 months. Two analyses were conducted, a whole-group analysis across all 65 participants and a subgroup analysis contrasting the four treatment variants.The whole-group analysis showed a significant treatment effect, which was largely sustained after one year. The subgroup analysis revealed a mixed picture: while improvements against the baseline period were observed in all four subgroups, 180 minutes of daily shaping training coupled with the constraint yielded better outcome on the MAL but not the WMFT, while for 90 minutes of training the level of improvement was similar for those who wore the constraint and those who did not. Together these results suggest that, at least in those patients available for follow up measures, modified CI therapy induces sustained improvements in motor function in patients with chronic low-functioning hemiparesis. The absence of clear differences between the four treatment variants points to a complex relationship between the length of daily shaping training and the constraint in this patient group which is likely to be

On the nature of the symbiotic binary CI Cygni

International Nuclear Information System (INIS)

Kenyon, S.J.; Oliversen, N.A.; Mikolajewska, J.; Mikolajewski, M.; Stencel, R.E.

1991-01-01

An analysis of ultraviolet and optical spectroscopy is presented for the symbiotic binary CI Cyg. This system contains an M5 II asymptotic branch giant Mg of about 1.5 solar mass, transfering material at a few times 0.00001 solar mass/yr into a large accretion disk surrounding a main-sequence star with Mh of about 0.5 solar mass. A boundary layer at the inner edge of the disk photoionizes a small nebula approximately confined to the Roche volume of the accreting star. An extended, more highly ionized region forms when material ejected from the disk interacts with the red giant wind. 115 refs

Free Surface of the Liquid-Gas Phase Separation as a Measuring Membrane of a Device for Measuring Small Hydrostatic Pressure Difference Values / Powierzchnia Swobodna Rozdziału Faz Ciecz-Gaz Jako Membrana Pomiarowa Urządzenia Do Pomiaru Małych Wartości Różnicy Ciśnienia Hydrostatycznego

Science.gov (United States)

Filipek, Wiktor; Broda, Krzysztof; Branny, Marian

2015-03-01

napisanego w języku Delphi autorskiego programu do obróbki numerycznej zdjęć. Występujące trudności ilustruje rysunek 2 przedstawiający przesunięcie linii odniesienia w trzech kolejno po sobie wykonanych zdjęciach. Następnie omówiono sposób przygotowania stanowiska do pomiarów oraz sposób ich przeprowadzania czego ilustracją są rysunki 3 i 4. Przedstawiono występujące problemy oraz zastosowane sposoby ich rozwiązania. Zarejestrowany przykładowy obraz po przejściu promienia lasera przez badaną strukturę dla wybranych wartości różnicy ciśnień hydrostatycznych uzyskany za pomocą kulek ceramicznych przedstawiono na rysunku 5. Rysunek 6 wyjaśnia metodę obróbki numerycznej zdjęć w oparciu o autorski program i zależności (1),(2),(3). Na rysunkach 7 i 9 zestawiono otrzymane krzywe zmienności intensywności barw uzyskane w trakcie opracowania numerycznego. Zwrócono także uwagę na rozkład zmian intensywności barw dla różnicy między powierzchniami swobodnymi cieczy w cylindrach (Rys. 8-11) dla wybranych serii pomiarowych. W dalszej części artykułu dokonano analizy otrzymanych obrazów zwracając uwagę na włączenie metody transformacji Fouriera lub "Falkowej" (Ziółko, 2000) do numerycznej analizy posiadanych danych (Rys. 12-14). Na rysunku 12 pokazano wybrane trzy zależności opisujące zmienność natężania barwy w funkcji położenia ramki (1), dla których dokonano transformacji Fouriera według zależności (3). Analizy dokonano metodą arytmetyczna Perry'ego (Ziółko, 2000) w okienku o szerokości n = 2300 przyjmując jako położenie startowe wartość x = 1600. Rysunek 13 przedstawia wartości współczynnika Ak a rys.14 przedstawia wartości kąta przesunięcia jk dla pierwszych 58 harmonicznych. Prace nad udoskonaleniem metody trwają. W dalszej części artykułu autorzy podsumowują osiągnięte wyniki zwracając uwagę na uzyskaną precyzję pomiarów oraz korzystne zastosowanie powierzchni swobodnej rozdziału faz

Badania wytrzymałości resztkowej gruntów spoistych z terenów osuwiskowych okolic Szymbarku k. Gorlic

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Katarzyna Staromłyńska

2017-02-01

Full Text Available W pracy przedstawiono wyniki badań wytrzymałości resztkowej gruntów spoistych pochodzących z terenów osuwiskowych okolic Szymbarku k. Gorlic. Badania przeprowadzone zostały w aparacie bezpośredniego ścinania na próbkach o przekroju 60 × 60 mm. Zastosowano dwie prędkości ścinania 0,05 i 0,1 mm • min–1, każda próbka była ścinana sześciokrotnie, a zakres poziomych odkształceń próbek wynosił 20%. Badania wykazały, że resztkowa wytrzymałość na ścinanie wzdłuż wytworzonej płaszczyzny osłabienia stanowi 52–78% jego wytrzymałości maksymalnej, a do wytworzenia płaszczyzny osłabienia niezbędne jest co najmniej 5-krotne ścinanie próbki. Wpływ prędkości ścinania miał niejednoznaczny wpływ na otrzymane wartości wytrzymałości resztkowej. Wykazano, że stosując do uzyskanych wyników badań liniową interpretację równania Coulomba-Mohra otrzymano niezerowe wartości spójności resztkowej. W związku z tym dla ograniczenia wpływu tego parametru na ocenę stateczności należałoby stosować nieliniową obwiednię wytrzymałościową, do której opisu można zastosować przedstawione w pracy równanie Lade.

Photocatalytic degradation of Maxilon C.I. basic dye using CS/CoFe_2O_4/GONCs as a heterogeneous photo-Fenton catalyst prepared by gamma irradiation

International Nuclear Information System (INIS)

Al-Kahtani, Abdullah A.; Abou Taleb, Manal F.

2016-01-01

Highlights: • CS/CF/GONCs were synthesized via γ-irradiation and used as a heterogeneous photo-Fenton catalyst. • It can degrade Maxilon C.I. basic dye under sunlight irradiation. • A possible degradation pathway of Maxilon C.I. Basic was proposed. • The degradation of Maxilon follows pseudo-first-order kinetics. • The catalyst can be separated by an external magnetic field. • Cyclic degradation tests show the catalyst is highly active, stable and recoverable. - Abstract: CS/CF/GONCs were synthesized via gamma irradiation cross-linking method with the aid of sonication. The nanocomposites exhibited a photo-Fenton catalytic feature for the degradation of Maxilon C.I. basic dye in aqueous medium using sunlight. The effects of pH, H_2O_2 concentration, and dosage of the catalyst, on the degradation rates of the dyes were examined. The optimal degradation rate was reached with 10 mM H_2O_2 at pH 9.5. It was verified that the Maxilon C.I. basic dye degradation rate fits a pseudo-first-order kinetics for different initial concentrations of Maxilon C.I. dye. Fourth cyclic tests for Maxilon C.I. degradation showed that the magnetic catalyst was very stable, recoverable, highly active, and easy to separate using an external magnet. Hence, this magnetic catalyst has potential use in organic pollutant removal.

A problemática dos organismos geneticamente modificados e a formação científica do cidadão comum: um estudo com manuais escolares de Ciências Naturais do 9º ano adotados em Portugal

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Luís Dourado

2014-12-01

Full Text Available Uma das aplicações da biotecnologia são os organismos geneticamente modificados (OGM, os quais têm uma utilização cada vez maior, apresentando vantagens, mas, também, sendo referidos como organismos potencialmente perigosos. Correspondendo a esses factos, os manuais de ciências dedicam algumas das suas páginas à biotecnologia, sendo os OGMs um dos aspetos focados. Nesse sentido e considerando a importância que o manual escolar tem na educação em ciências, procedemos a um estudo que envolveu a análise dos manuais escolares de ciências naturais do 9º ano adotados em Portugal, na parte respeitante aos OGMs. Neste estudo verificou-se que os manuais nem sempre apresentam a informação correta e necessária, de forma adequada, e que nem sempre lhe dão o devido destaque. Dado que a nossa investigação revela a existência de falhas ao nível dos manuais, as conclusões obtidas podem contribuir para uma melhoria dos mesmos e, consequentemente, da qualidade da educação em ciências.

Development of Xi'an-CI package – applying the hole–particle symmetry in multi-reference electronic correlation calculations

Science.gov (United States)

Suo, Bingbing; Lei, Yibo; Han, Huixian; Wang, Yubin

2018-04-01

This mini-review introduces our works on the Xi'an-CI (configuration interaction) package using graphical unitary group approach (GUGA). Taking advantage of the hole-particle symmetry in GUGA, the Galfand states used to span the CI space are classified into CI subspaces according to the number of holes and particles, and the coupling coefficients used to calculate Hamiltonian matrix elements could be factorised into the segment factors in the hole, active and external spaces. An efficient multi-reference CI with single and double excitations (MRCISD) algorithm is thus developed that reduces the storage requirement and increases the number of correlated electrons significantly. The hole-particle symmetry also gives rise to a doubly contracted MRCISD approach. Moreover, the internally contracted Gelfand states are defined within the CI subspace arising from the hole-particle symmetry, which makes the implementation of internally contracted MRCISD in the framework of GUGA possible. In addition to MRCISD, the development of multi-reference second-order perturbation theory (MRPT2) also benefits from the hole-particle symmetry. A configuration-based MRPT2 algorithm is proposed and extended to the multi-state n-electron valence-state second-order perturbation theory.

Partial Factors in Modelling of Steel Structures Reliability According to Eurocodes / Współczynniki Częściowe W Eurokodowym Modelu Niezawodności Konstrukcji Stalowych

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Stachura Zbigniew

2015-03-01

Full Text Available Stan graniczny nośności konstrukcji, projektowanej w tradycyjnym podejściu na podstawie efektów oddziaływań jest oceniany z niezawodnościowego modelu szeregowego. Kalibrację współczynników częściowych do nośności przeprowadza się wówczas na podstawie analizy niezawodności pojedynczego elementu konstrukcji (pręta lub węzła. Eurokod stalowy [4] wprowadził zasady projektowania bazujące na bardziej złożonych modelach nośności niż w [8], gdyż stan graniczny można ocenić na podstawie warunku stateczności technicznej podukładu konstrukcji lub w ogólności, jak przedstawia to warunek (2.1 - na podstawie punktu granicznego na ścieżce równowagi wyznaczonej dla nieidealnego modelu całej konstrukcji. Pojawia się pytanie, czy stosowanie do nośności wyznaczonej na podstawie bardziej złożonych modeli mechaniki konstrukcji współczynników częściowych wyspecyfikowanych do oceny nośności pojedynczych elementów prowadzi do bezpiecznych oszacowań. Kalibracja współczynników częściowych w metodzie stanów granicznych może być dokonana przy różnych założeniach wyjściowych. Model niezawodności i ogólne zasady przyjętego w eurokodach rozdziału docelowego wskaźnika niezawodności na składowe odnoszące się do ustalenia obliczeniowych oddziaływań i ich kombinacji oraz do ustalania nośności obliczeniowej zostały podane w eurokodzie [1]. W artykule przedstawiono zagadnienia dotyczące przyjęcia współczynników częściowych do nośności układu lub podukładu konstrukcyjnego. Opisano eurokodową procedurę wykorzystującą wyniki badań doświadczalnych do kalibracji współczynników częściowych do nośności.

Fenomenologia e Ciência. Actas do IVº Congresso Internacional da AFFEN – IIIº Congresso Luso-Brasileiro de Fenomenologia

OpenAIRE

Borges-Duarte, Irene; Pardelha, Irene

2014-01-01

Este volume reune os textos apresentados ao IVº Congresso Internacional da AFFEN – IIIº Congresso Luso-Brasileiro de Fenomenologia, em 5 secções: Ciência, Técnica, Psicoterapia fenomenológica, Questões da Fenomenologia Husserliana e Outras fenomenologias. Tendo como temática unificadora «Fenomenologia e Ciência», integram-se trabalhos sobre aplicação da metodologia fenomenológica e hermenêutica às questões da ciência e da técnica, e a âmbitos científicos particulares como a Psicologia, a Soci...

Bioética clínica: ciência e humanidade = Clinical bioethics: science and humanity

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Batista, Cristiano Corrêa

2005-01-01

Resultados e conclusão: Nossa conclusão é de a medicina não ser apenas uma ciência, mas também uma arte. Ela exige, em situações particulares, elaborar julgamentos de valor. A Bioética Clínica, surge para guiar caminhos combinando o conhecimento técnico- científico das ciências biomédicas com o conhecimento filosófico. Por meio da Bioética Clínica é possível resgatar os aspectos humanos da arte da medicina

Percepcja postaw rodzicielskich przez młodzież z gotowością anorektyczną

OpenAIRE

Jałocha, Patrycja

2012-01-01

Wzrost zainteresowania problematyką zaburzeń odżywiania jest uzasadniony ze względu na jednostkowe, ale i społeczne konsekwencje wynikające z nieprawidłowości w obszarze realizowania potrzeby pokarmowej. Ponadto dane epidemiologiczne wskazują na zwiększanie się liczebności oraz spadek wieku osób z objawami zaburzeń łaknienia. Przyczyn tego może być wiele, ponieważ anoreksja ma wieloczynnikowe podłoże. W literaturze przedmiotu podkreśla się znaczenie relacji w rodzinach anorektycznych. Realiz...

Technical note: A new day- and night-time Meteosat Second Generation Cirrus Detection Algorithm MeCiDA

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W. Krebs

2007-12-01

Full Text Available A new cirrus detection algorithm for the Spinning Enhanced Visible and Infra-Red Imager (SEVIRI aboard the geostationary Meteosat Second Generation (MSG, MeCiDA, is presented. The algorithm uses the seven infrared channels of SEVIRI and thus provides a consistent scheme for cirrus detection at day and night. MeCiDA combines morphological and multi-spectral threshold tests and detects optically thick and thin ice clouds. The thresholds were determined by a comprehensive theoretical study using radiative transfer simulations for various atmospheric situations as well as by manually evaluating actual satellite observations. The cirrus detection has been optimized for mid- and high latitudes but it could be adapted to other regions as well. The retrieved cirrus masks have been validated by comparison with the Moderate Resolution Imaging Spectroradiometer (MODIS Cirrus Reflection Flag. To study possible seasonal variations in the performance of the algorithm, one scene per month of the year 2004 was randomly selected and compared with the MODIS flag. 81% of the pixels were classified identically by both algorithms. In a comparison of monthly mean values for Europe and the North-Atlantic MeCiDA detected 29.3% cirrus coverage, while the MODIS SWIR cirrus coverage was 38.1%. A lower detection efficiency is to be expected for MeCiDA, as the spatial resolution of MODIS is considerably better and as we used only the thermal infrared channels in contrast to the MODIS algorithm which uses infrared and visible radiances. The advantage of MeCiDA compared to retrievals for polar orbiting instruments or previous geostationary satellites is that it permits the derivation of quantitative data every 15 min, 24 h a day. This high temporal resolution allows the study of diurnal variations and life cycle aspects. MeCiDA is fast enough for near real-time applications.

A evolução da ciência da informação a partir de conceitos-sinônimos empregados na obra ciência da informação ou informática?

OpenAIRE

Marco Donizete Paulino da Silva

2012-01-01

Este trabalho foi desenvolvido a partir de uma análise bibliográfica sobre artigos que compõem o livro Informática ou Ciência da Informação?, organizado por Hagar Espanha Gomes, em 1980. Estrutura-se como projeto de revisão histórica em que se narra as impressões estabelecidas durante leitura da obra, evidenciando os termos considerados relevantes e coletando-os para análise posterior do contexto em que estes foram empregados. Deduziu-se, dessa análise, a forma como a Ciência da Informação fo...

Polska prasa tabletowa – modele biznesowe dystrybucji treści

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Krzysztof Flasiński

2012-02-01

Full Text Available Autor przeanalizował aplikacje spełniające trzy warunki: przeznaczone na tablety marki iPad, dostępne w sklepie App Store oraz powiązane z polskojęzycznymi tytułami prasowymi. Artykuł przedstawia kompletną panoramę polskiej prasy tabletowej. Ujętych zostało 38 aplikacji dostępnych 30 września 2011 r. Po zbadaniu wszystkich programów utworzono „mapę modeli biznesowych dystrybucji treści”. Czynnikiem decydującym o umieszczeniu na niej aplikacji prasowych była forma dystrybucji treści (płatna/bezpłatna oraz  rodzaj udostępnianej treści (powiązana z wydaniem drukowanym/powiązana z wydaniem online. Z analizy wynika, że 11 redakcji udostępnia płatne wydanie print, 10 – bezpłatne wydanie online, 7 – bezpłatne wydanie print, 3 – bezpłatne wydanie online oraz płatne wydanie print, jedna – oba wydania bezpłatnie, i jedna – oba wydania płatnie. Wywód uzupełniają dodatkowe dane: chronologiczna lista aplikacji prasowych według daty ukazania, wykaz kosztów korzystania z poszczególnych aplikacji, aktywność wydawców prasowych w App Store w rozbiciu na miesiące oraz kwartały.

Emission Characteristics of a CI Engine Running with a Range of Biodiesel Feedstocks

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Belachew Tesfa

2014-01-01

Full Text Available Currently, alternative fuels are being investigated in detail for application in compression ignition (CI engines resulting in exciting potential opportunities to increase energy security and reduce gas emissions. Biodiesel is one of the alternative fuels which is renewable and environmentally friendly and can be used in diesel engines with little or no modifications. The objective of this study is to investigate the effects of biodiesel types and biodiesel fraction on the emission characteristics of a CI engine. The experimental work was carried out on a four-cylinder, four-stroke, direct injection (DI and turbocharged diesel engine by using biodiesel made from waste oil, rapeseed oil, corn oil and comparing them to normal diesel. The fuels used in the analyses are B10, B20, B50, B100 and neat diesel. The engine was operated over a range of engine speeds. Based on the measured parameters, detailed analyses were carried out on major regulated emissions such as NOx, CO, CO2, and THC. It has been seen that the biodiesel types (sources do not result in any significant differences in emissions. The results also clearly indicate that the engine running with biodiesel and blends have higher NOx emission by up to 20%. However, the emissions of the CI engine running on neat biodiesel (B100 were reduced by up to 15%, 40% and 30% for CO, CO2 and THC emissions respectively, as compared to diesel fuel at various operating conditions.

40 CFR 63.6604 - What fuel requirements must I meet if I own or operate an existing stationary CI RICE?

Science.gov (United States)

2010-07-01

... I own or operate an existing stationary CI RICE? 63.6604 Section 63.6604 Protection of Environment....6604 What fuel requirements must I meet if I own or operate an existing stationary CI RICE? If you own or operate an existing non-emergency CI stationary RICE with a site rating of more than 300 brake HP...

A inteligência artificial no contexto das ciências cognitivas

OpenAIRE

Lira, Tércio Onofre de

2011-01-01

Atualmente existe uma vasta gama de aplicações na área da Inteligência Artificial, porém os progressos caminham a passos curtos no que diz respeito ao desenvolvimento de uma inteligência artificial forte. Esta dissertação busca elucidar a multidisciplinaridade das ciências cognitivas, à qual os estudos da inteligência artificial estão atrelados, por meio da apresentação sucinta, porém panorâmica, do histórico de cada especialidade ou área: neurociência cognitiva, filosofia da m...

[Dance projects as an integral part of CI rehabilitation and their impact on mental health: a pilot study].

Science.gov (United States)

Klink, B; Praetorius, M; Roder, S; Hintermair, M

2014-07-01

Alongside improvements in hearing and communication skills, the rehabilitation of children, adolescents and adults with a cochlear implant (CI) in recent years has increasingly taken into account mental health and quality of life issues. In the context of the programs offered, this study assesses the significance of dance for the mental health of adult clients with a CI. Eleven adult CI users participated in a dance project, which took place as a cooperation between the ENT University Hospital Heidelberg and the Baden State Theatre Karlsruhe. Participants were questioned at two different time points for assessment with the mental health scales (SPG). These scales measure seven different aspects of psychosocial well-being (including autonomy, willpower, affirmation of life and meaningfulness). Significant positive changes in the domains of affirmation of life, self-reflection and social integration were revealed by before and after comparisons; tendencies toward positive change were observed (p ≤ 0.10) in the domains of willpower, naturalness and meaningfulness. No changes were observed in the autonomy domain. The results indicate that the mental health of adult clients with a CI can be strengthened by dance as a complementary rehabilitation module. Concepts of CI rehabilitation should increasingly find anchor in the consideration of such arrangements for its range of offers.

Determinanty przestrzennego zróżnicowania płodności w Polsce w latach 1999-2009

OpenAIRE

Małgorzata Podogrodzka

2012-01-01

Obserwowane od lat zmiany w natężeniu dzietności oraz wzorca płodności w Polsce nie przebiegają podobnie według województw. Celem artykułu jest ukazanie tych przekształceń oraz określenie czynników je determinujących. Zakładamy, że w regionach charakteryzujących się wyższym zagrożeniem bezrobocia oraz „nowoczesnym” stylem życia będziemy mogli zaobserwować niższą płodność oraz wyższe zaawansowanie wzorca płodności. W przypadku zmiennych określających stabilność zatrudnienia oraz lepszą dostępn...

Używki w ciąży – alcohol = Stimulants in pregnancy – alcohol

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AGNIESZKA KONSTANCJA PAWŁOWSKA-MUC

2015-08-01

Używki w ciąży - alkohol Streszczenie Wprowadzenie. Spożywanie alkoholu kobiety w wieku rozrodczym jest problemem wielu krajów świata. Stwarza ono duże zagrożenie dla ich zdrowia prokreacyjnego, prawidłowego przebiegu ciąży, zdrowia noworodka i dziecka w późniejszym okresie jego życia. Cel pracy. Celem pracy było ukazanie skali problemu oraz skutków spożywania alkoholu przez kobiety w okresie ciąży. Skrócony opis stanu wiedzy. Z przeglądu piśmiennictwa wynika, iż skala problemu jest trudna do oszacowania. Negatywnych skutków jest zdecydowanie więcej niż pozytywnych. Dotychczas nie określono jeszcze bezpiecznej dawki alkoholu dla ciężarnych, a kobiet spożywających napoje alkoholowe w tym czasie jest wciąż za duża. Świadomość konsekwencji takich zachowań nie zawsze idzie w parze z całkowitą rezygnacją z picia alkoholu podczas ciąży. Podsumowanie. Istnieje potrzeba większego niż dotychczas angażowania się pracowników medycznych (lekarzy położników i położnych w działalność nie tylko informacyjną, lecz także edukacyjną i wspierającą.   Słowa kluczowe: alkohol, ciąża, płód, zdrowie.                                             Stimulants in pregnancy - alcohol Abstract Introduction. Alcohol consumption by women in the reproductive period is a current problem in many countries around the world. It poses a great threat to their reproductive health, the correct parturition, the health of the newborn and the child in the later part of its life. Aim. It was the aim of this work to present the scale of the problem as well as the results of women’s alcohol consumption during pregnancy. Brief description of the state of the art. The review of the bibliography indicates that the scale of the problem is hard to assess. Negative effects are much more prevalent than the positive ones. A safe unit dose for pregnant women has not yet been established and the number of women

Nieswoiste zapalenia jelit a płodność, przebieg ciąży, porodu i karmienie piersią

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Dorota Szczeblowska

2011-07-01

Full Text Available Do nieswoistych zapaleń jelit zaliczamy wrzodziejące zapalenie jelita grubego i chorobę Leśniowskiego-Crohna. Ponieważ szczyt zapadalności na te choroby przypada między 15. a 35. rokiem życia, a więc dotyczy osób w okresie prokreacyjnym, rodzi się szereg pytań i wątpliwości na temat wpływu tych schorzeń oraz ich leczenia na płodność, a także przebieg ciąży, porodu i ewentualne bezpieczeństwo późniejszego karmienia piersią. W opracowaniu zostały przedstawione zasady leczenia nieswoistych zapaleń jelit u mężczyzn oraz u kobiet planujących posiadanie potomstwa, jak również kobiet będących w ciąży i karmiących. Należy podkreślić, że sam fakt rozpoznania nieswoistych chorób zapalnych jelit nie jest bezpośrednim przeciwwskazaniem do zajścia w ciążę. Ciąża nie stanowi również wskazania do przerwania leczenia tych chorób, tj. nieswoistych zapaleń jelit, gdyż zaostrzenie ich przebiegu wiąże się z większym ryzykiem dla potomstwa w porównaniu z niebezpieczeństwem wynikają- cym z wdrożenia nawet agresywnego, a skutecznego leczenia. Aktywacja tych chorób zwiększa zarówno ryzyko poronień, jak i porodów przedwczesnych oraz wewnątrzmacicznego obumarcia płodu. Nieprzerwana farmakoterapia nieswoistych zapaleń jelit środkami niemającymi działania karcynogennego ma istotny wpływ na urodzenie zdrowego dziecka. Optymalnym czasem do zajścia w ciążę w takim przypadku jest okres po trwającej przynajmniej 3 miesiące remisji choroby. W okresie planowania ciąży zaleca się suplementację kwasu foliowego.

School performance and wellbeing of children with CI in different communicative-educational environments

NARCIS (Netherlands)

Langereis, M.C.; Vermeulen, A.M.

2015-01-01

OBJECTIVES: This study aimed to evaluate the long term effects of CI on auditory, language, educational and social-emotional development of deaf children in different educational-communicative settings. METHODS: The outcomes of 58 children with profound hearing loss and normal non-verbal cognition,

Estabilidad temporal del C.I. y potencial de aprendizaje en niños superdotados: implicaciones diagnósticas

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Mª Dolores Calero

2014-05-01

Full Text Available Tradicionalmente la determinación de la sobredotación se ha realizado con tests tradicionales de inteligencia. El principal argumento para hacerlo ha sido la estabilidad temporal de esta medida. En los últimos años algunos autores defienden una determinación temprana de la sobredotación en niños, aunque otros señalan que la determinación del C.I. en niños pequeños arroja un número importante de falsos positivos debido a la variabilidad de la medida de la inteligencia por influencia de diferentes factores tales como la plasticidad cerebral, la estimulación, etc., por lo que proponen el uso de índices complementarios para el diagnóstico de sobredotación. En este trabajo se realiza un estudio longitudinal de dos años a 49 niños de entre 5 y 9 años, -inicialmente identificados como superdotados-, para comprobar la estabilidad de su C.I. y de otras medidas tales como el potencial de aprendizaje y la memoria de trabajo. Los resultados muestran como las medidas de potencial de aprendizaje y memoria de trabajo permanecen estables en el tiempo mientras que el C.I. de un grupo de niños de menor edad no se mantiene en dicho periodo. Estos resultados señalan la utilidad de las medidas de P.A. como un índice complementario en la determinación de la sobredotación en niños pequeños.

Biological, serological and molecular techniques to xanthomonas axonopodis pv. Ci tri Asymptomatic detection

International Nuclear Information System (INIS)

Peyrou, M.; Del Campo, R.; Russi, P.; Mara, H.; Rigamonti, N.; Larrechart, L.; Perez, E.

2012-01-01

Xanthomonas axonopodis pv. ci tri (X ac) produces citrus canker disease in all citrus commercial species. The bacteria can be disseminated through vegetative propagation material in asymptomatic form. To optimize bacteria detection techniques applicable to asymptomatic citrus plant tissue routine analysis, ELISA, Immunofluorescence, Pcr, qRT P CR and host plant inoculation (bioassay) diagnostic techniques were compared. Tests were made from decimal dilutions between 108 uf6.ml-1 and 102 ufc.mL-1 using a pure culture of 49b strain.The detection level obtained was 1.8 x 102 ufc.mL-1 using Inmunofluorescence; 1.8x104 ufc.mL-1 with indirect ELISA, 1.8 x 103 ufc.mL-1 by means of PCR; 10 ufc.mL-1 through of qRT P CR and 230 ufc.mL-1 in sour orange inoculated plants. The experiment was repeated at least three times for each technique. Considering this result, and taking into account that sensitivity, practicity and cost, are important when a great number of plants need to be tested, the PCR and inoculation in host plants were those that met the best characteristics to be evaluated in asymptomatic plant material

Biosorption of C.I. Direct Blue 199 from aqueous solution by nonviable Aspergillus niger

International Nuclear Information System (INIS)

Xiong Xiaojing; Meng Xuejiao; Zheng Tianling

2010-01-01

The capacity and mechanism with which nonviable Aspergillus niger removed the textile dye, C.I. Direct Blue 199, from aqueous solution was investigated using different parameters, such as initial dye concentration, pH and temperature. In batch experiments, the biosorption capacity increased with decrease in pH, and the maximum dye uptake capacity of the biosorbent was 29.96 mg g -1 at 400 mg L -1 dye concentration and 45 deg. C. The Langmuir and Freundlich models were able to describe the biosorption equilibrium of C.I. Direct Blue 199 onto the fungal biomass. Biosorption followed a pseudo-second order kinetic model with high correlation coefficients (r 2 > 0.99). Thermodynamic studies revealed that the biosorption process was successful, spontaneous and endothermic in nature.

Możliwości polderyzacji obszaru zawala w rejonie Stężycy nad Wisłą

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Anna Sosnowska

2016-12-01

Full Text Available Temat ochrony przeciwpowodziowej, w tym polderów, jest zwykle podnoszony przy okazji każdej większej powodzi i po pewnym czasie, gdy zastosowano już doraźne środki naprawcze, dyskusja cichnie. Poldery jako obiekty hydrotechniczne, mające za zadanie przejąć szczyt fali powodziowej, wzbudzają wiele przeciwstawnych emocji. Z jednej strony uważa się, że są to obiekty, które mogą skutecznie uzupełniać system ochrony przeciwpowodziowej i pozytywnie wpływać na środowisko przyrodnicze. Z drugiej strony wysokie koszty, niska efektywność i wiele innych elementów sprawiają, że nie jest to popularna forma ochrony przed powodzią. W części obliczeniowej pracy skupiono się na nieistniejącym polderze w Stężycy o całkowitej pojemności równej około 24 mln m3. Model odcinka Wisły z uwzględnieniem istnienia polderu wykonano w programie HEC-RAS. Obliczenia dotyczyły szybkości napełniania tego zbiornika przy trzech różnych wariantach przepływu nieustalonego i przy różnych długościach przelewu na wlocie do polderu. Symulacje wykazały, że w krytycznym przypadku niezbędny byłby wlot o długości ok. 400 m, aby w całości napełnić polder podczas trwania wezbrania. W drugiej części pracy podjęto dyskusję na temat pozytywnych i negatywnych aspektów budowy polderów.

O que é Ciência da Informação?

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Carlos Alberto Ávila Araújo

2014-12-01

Full Text Available Introdução: Apresenta um panorama da Ciência da Informação em três momentos. Inicialmente, seu surgimento e consolidação na década de 1960, como confluência de vários fatos: a distinção em relação à Arquivologia, à Biblioteconomia e à Museologia; a relação com a Documentação; a ocupação do espaço institucional da Biblioteconomia; as atividades dos primeiros “cientistas da informação”; as tecnologias da informação; e o uso da Teoria Matemática. Objetivo: Analisar a ampliação vivida nas décadas seguintes com o desenvolvimento de subáreas, das caracterizações do campo e da evolução do conceito de informação. Metodologia: Revisão de Literatura. Resultados: São apresentadas as tendências contemporâneas: as sistematizações da área, os três modelos para o estudo da informação e o desafio recente de diálogo com a Arquivologia, a Biblioteconomia e a Museologia. Conclusões: muitos processos e eventos aconteceram no campo da Ciência da Informação nestes últimos 45 anos. Diferentes subáreas foram formadas, conceitos formulados e reformulados, caracterizações problematizadas e discutidas, relações com outros campos de conhecimento tensionadas e concretizadas.

Trudności we wprowadzaniu reformy gimnazjalnej na obszarach wiejskich

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Aneta Sobotka

2016-09-01

Full Text Available Wprowadzone w 1999 r. gimnazja miały służyć wyrównywaniu szans edukacyjnych dzieci z terenów wiejskich. Jednym z założeń reformy było stworzenie dużych, samodzielnych i dobrze wyposażonych gimnazjów, w których wspólnie uczyliby się absolwenci wszystkich szkół podstawowych z terenu gminy. Po kilkunastu latach funkcjonowania gimnazja pod względem organizacyjnym bardzo się zróżnicowały – w niektórych gminach, zgodnie z założeniami reformatorów, ciągle funkcjonują duże i samodzielne gimnazja, jednak w części gmin bardzo małe gimnazja działają w zespole ze szkołą podstawową, gdzie uczniowie przez dziewięć lat nie zmieniają kolegów, nauczycieli i środowiska. Na podstawie ośmiu studiów przypadku gmin wiejskich pokazano w artykule proces kształtowania sieci gimnazjów w pierwszych latach reformy systemu szkolnego. Próbowano zrozumieć, jakie czynniki zadecydowały o wytworzeniu się tych dwóch modeli gimnazjum. Przedstawione studia przypadku pokazują, że sieć szkolna jest nie tyle wynikiem realizacji planów tworzenia sieci szkolnej przez władze lokalne, ile raczej wynikiem gry pomiędzy lokalnymi władzami a lokalnymi społecznościami.

Bioinformatic analysis of the distribution of inorganic carbon transporters and prospective targets for bioengineering to increase Ci uptake by cyanobacteria.

Science.gov (United States)

Gaudana, Sandeep B; Zarzycki, Jan; Moparthi, Vamsi K; Kerfeld, Cheryl A

2015-10-01

Cyanobacteria have evolved a carbon-concentrating mechanism (CCM) which has enabled them to inhabit diverse environments encompassing a range of inorganic carbon (Ci: [Formula: see text] and CO2) concentrations. Several uptake systems facilitate inorganic carbon accumulation in the cell, which can in turn be fixed by ribulose 1,5-bisphosphate carboxylase/oxygenase. Here we survey the distribution of genes encoding known Ci uptake systems in cyanobacterial genomes and, using a pfam- and gene context-based approach, identify in the marine (alpha) cyanobacteria a heretofore unrecognized number of putative counterparts to the well-known Ci transporters of beta cyanobacteria. In addition, our analysis shows that there is a huge repertoire of transport systems in cyanobacteria of unknown function, many with homology to characterized Ci transporters. These can be viewed as prospective targets for conversion into ancillary Ci transporters through bioengineering. Increasing intracellular Ci concentration coupled with efforts to increase carbon fixation will be beneficial for the downstream conversion of fixed carbon into value-added products including biofuels. In addition to CCM transporter homologs, we also survey the occurrence of rhodopsin homologs in cyanobacteria, including bacteriorhodopsin, a class of retinal-binding, light-activated proton pumps. Because they are light driven and because of the apparent ease of altering their ion selectivity, we use this as an example of re-purposing an endogenous transporter for the augmentation of Ci uptake by cyanobacteria and potentially chloroplasts.

Powrócić do początku, czyli jak kultura maskuje swoją zmienność?

Directory of Open Access Journals (Sweden)

Jan Kajfosz

2015-12-01

Full Text Available Return to the beginnings, or how culture masks its changes?  The aim of this essay is to describe cognitive mechanisms on which imagined intersubjectively important continuities and discontinuities in culture are based, and thus allow creating and transforming collective identities. The author uses tools of phenomenology and semiotics to provide answers to a few questions concerning cognitive mechanisms of memory and symbolic violence as well as the ways in which culture can change and adapt to current socio-political needs. These issues pertain also to nation and national identities.   Powrócić do początku, czyli jak kultura maskuje swoją zmienność?  Celem przyczynku jest próba odpowiedzi na pytanie, na jakich kognitywnych mechanizmach opiera się konstruowanie wyobrażonych, intersubiektywnie ważnych ciągłości i nieciągłości w kulturze, będących podstawą tworzenia i przetwarzania tożsamości zbiorowych. Posługując się narzędziami fenomenologii i semiotyki, autor chce dostarczyć odpowiedzi na następujące pytania: Na podstawie jakich kognitywnych mechanizmów pamięć – wraz z jej społecznymi ramami – może się dostosowywać do aktualnie ważnych społeczno-politycznych potrzeb? Na jakich kognitywnych mechanizmach opiera się przemoc symboliczna? W jaki sposób kultura potrafi eliminować pamięć o własnych przemianach? – Propozycje zawierające się w artykule wskazują na retoryczny (perswazyjny, legitymizacyjny i światotwórczy – czyli pragmatyczny – wymiar konotacji, a zwłaszcza „zgęszczeń konotacji” nazywanych przez R. Barthesa mitem. Podstawową funkcję eksplanacyjną w odniesieniu do pytań o kognitywne mechanizmy społecznego konstruowania przeszłości (inaczej: „początku” oprócz konotacji mają tu takie kategorie, jak percepcja magiczna i myślenie magiczne.

A SBPC e a informação ambiental no Brasil: o papel da revista Ciência Hoje

Directory of Open Access Journals (Sweden)

Antonio Teixeira De Barros

Full Text Available Analisa u informação ambiental divulgada pela revista Ciência Hoje, editada pela Sociedade Brasileira para o Progresso da Ciência (SBPC, desde o primeiro número da revista até a realização da Eco 92. A divulgação concentra-se nos estudos de avaliação de impactos e efeitos da degradação ambiental e nos temas globais da agenda ecológica. O didatismo é uma das características principais de Ciência Ho je, com o intuito de facilitar a leitura por parte do público leigo.

Improving Vegetable Oil Fueled CI Engine Characteristics Through Diethyl Ether Blending

KAUST Repository

Vedharaj, S.

2016-12-01

In this research, the flow and ignition properties of vegetable oil (VO) are improved by blending it with diethyl ether (DEE). DEE, synthesized from ethanol, has lower viscosity than diesel and VO. When DEE is blended with VO, the resultant DEEVO mixtures have favorable properties for compression ignition (CI) engine operation. As such, DEEVO20 (20% DEE + 80% VO) and DEEVO40 (40% DEE + 60% VO) were initially considered in the current study. The viscosity of VO is 32.4*10−6 m2/s; the viscosity is reduced with the increase of DEE in VO. In this study, our blends were limited to a maximum of 40% DEE in VO. The viscosity of DEEVO40 is 2.1*10−6 m2/s, which is comparable to that of diesel (2.3*10−6 m2/s). The lower boiling point and flash point of DEE improves the fuel spray and evaporation for DEEVO mixtures. In addition to the improvement in physical properties, the ignition quality of DEEVO mixtures is also improved, as DEE is a high cetane fuel (DCN = 139). The ignition characteristics of DEEVO mixtures were studied in an ignition quality tester (IQT). There is an evident reduction in ignition delay time (IDT) for DEEVO mixtures compared to VO. The IDT of VO (4.5 ms), DEEVO20 (3.2 ms) and DEEVO40 (2.7 ms) was measured in IQT. Accordingly, the derived cetane number (DCN) of DEEVO mixtures increased with the increase in proportion of DEE. The reported mixtures were also tested in a single cylinder CI engine. The start of combustion (SOC) was advanced for DEEVO20 and DEEVO40 compared to diesel, which is attributed to the high DCN of DEEVO mixtures. On the other hand, the peak heat release rate decreased for DEEVO mixtures compared to diesel. Gaseous emissions such as nitrogen oxide (NOX), total hydrocarbon (THC) and smoke were reduced for DEEVO mixtures compared to diesel. The physical and ignition properties of VO are improved by the addition of DEE, and thus, the need for the trans-esterification process is averted. Furthermore, this blending strategy is simpler

Improving Vegetable Oil Fueled CI Engine Characteristics Through Diethyl Ether Blending

KAUST Repository

Vedharaj, S.; Vallinayagam, R.; Sarathy, Mani; Dibble, Robert W.

2016-01-01

In this research, the flow and ignition properties of vegetable oil (VO) are improved by blending it with diethyl ether (DEE). DEE, synthesized from ethanol, has lower viscosity than diesel and VO. When DEE is blended with VO, the resultant DEEVO mixtures have favorable properties for compression ignition (CI) engine operation. As such, DEEVO20 (20% DEE + 80% VO) and DEEVO40 (40% DEE + 60% VO) were initially considered in the current study. The viscosity of VO is 32.4*10−6 m2/s; the viscosity is reduced with the increase of DEE in VO. In this study, our blends were limited to a maximum of 40% DEE in VO. The viscosity of DEEVO40 is 2.1*10−6 m2/s, which is comparable to that of diesel (2.3*10−6 m2/s). The lower boiling point and flash point of DEE improves the fuel spray and evaporation for DEEVO mixtures. In addition to the improvement in physical properties, the ignition quality of DEEVO mixtures is also improved, as DEE is a high cetane fuel (DCN = 139). The ignition characteristics of DEEVO mixtures were studied in an ignition quality tester (IQT). There is an evident reduction in ignition delay time (IDT) for DEEVO mixtures compared to VO. The IDT of VO (4.5 ms), DEEVO20 (3.2 ms) and DEEVO40 (2.7 ms) was measured in IQT. Accordingly, the derived cetane number (DCN) of DEEVO mixtures increased with the increase in proportion of DEE. The reported mixtures were also tested in a single cylinder CI engine. The start of combustion (SOC) was advanced for DEEVO20 and DEEVO40 compared to diesel, which is attributed to the high DCN of DEEVO mixtures. On the other hand, the peak heat release rate decreased for DEEVO mixtures compared to diesel. Gaseous emissions such as nitrogen oxide (NOX), total hydrocarbon (THC) and smoke were reduced for DEEVO mixtures compared to diesel. The physical and ignition properties of VO are improved by the addition of DEE, and thus, the need for the trans-esterification process is averted. Furthermore, this blending strategy is simpler

Branding Grenlandii formą ekspresji tożsamości narodowej?

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Dominika Bartnik-Światek

2016-01-01

Full Text Available Branding Greenland as a form of expression of national identity? In the times of globalisation there is a tendency for countries to differentiate from others. More and more governments decide to launch professional nation branding campaigns in order to communicate to a broad public what a particular country has to offer as well as what values and images it wants to be associated with. Greenland is an example of a country that after a long period of colonisation and establishing self-government, in 2009 began to redefine its identity and reveal it to the world. A branding campaign has been implemented to communicate a newly defined image of Greenland. This campaign has been carried out using mainly social media and the tools that the Internet has to offer. The aim of this paper is to explore the concept of nation branding and to define the relation between nation branding and national identity. The purpose is also to analyse what images of Greenland as a brand are presented by “Pioneering nation” campaign.   Branding Grenlandii formą ekspresji tożsamości narodowej? W czasach globalizacji poszczególne państwa starają się wyróżnić na tle innych państw. Coraz więcej rządów decyduje się na przeprowadzenie profesjonalnych kampanii brandingowych, po to by podkreślić swoją wyjątkowość oraz to, że mają dużo do zaoferowania. Grenlandia to przykład państwa, które po długim okresie skolonizowania i po uzyskaniu autonomii w 2009 roku, zaczęło na nowo definiować swoją tożsamość i komunikować ją światu. W tym celu wdrożona została kampania, która wykorzystywała głównie media społecznościowe oraz inne narzędzia, które zapewnia internet. Celem niniejszego artykułu jest zbadanie zależności między brandingiem narodowym a tożsamością narodową, jak też analiza obrazu Grenlandii jako marki konstruowanej w kampanii „Pioneering nation”.

A Ciência de Freud: introdução ao problema da cientificidade da psicanálise

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Nathalia Sisson

2010-04-01

Full Text Available Apresenta-se primeiramente a concepção de Freud do que seria a Ciência e em que constituiria a atividade cientifica, utilizando-se textos freudianos nos quais ele trabalha esse tema. Considera-se as noções de Naturwissenchaft e Geistwissenchaft para contextualizar a discussão sobre a cientificidade da Psicanálise à época de Freud. Confronta-se então a Ciência, como entendida por Freud, com as concepções de Popper e Bachelard, oriundos da Epistemologia. Posteriormente, apresentamos diferentes posições de psicanalistas, como Lacan e Kernberg, quanto ao mesmo tema, para mostrar como a compreensão do que seja a Ciência determina os posicionamentos quanto à relação entre esta e a Psicanálise.

Helminth parasites of freshwater fishes from Cuatro Ciénegas, Coahuila, in the Chihuahuan Desert of Mexico: inventory and biogeographical implications.

Science.gov (United States)

Aguilar-Aguilar, Rogelio; Martínez-Aquino, Andrés; Espinosa-Pérez, Héctor; Pérez-Ponce de León, Gerardo

2014-06-01

As part of an ongoing inventory of the helminth parasites of freshwater fishes in Mexico, 570 individual fish were collected between Apr 2008 and Oct 2011 in 26 localities along the Cuatro Ciénegas region in Coahuila State, northern Mexico. Seventeen species of hosts, mostly corresponding to Nearctic freshwater elements, were studied. A total of 8324 individual worms were collected during this survey, representing 25 species of helminths, of which 9 were digeneans, 3 monogeneans, 3 acanthocephalans, 9 nematodes and 1 cestode. Most of the records in this checklist represent new host or locality records. The information provided in this checklist may be helpful for our understanding of the biodiversity and historical biogeography of this host-parasite system, because in the Cuatro Ciénegas region occur a Nearctic freshwater fish fauna, along with Neotropical and endemic elements, and from a biogeographical point of view, this may represent a transitional area. © 2013 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and Wiley Publishing Asia Pty Ltd.

The Role of MOR and the CI Operator Sites on the Genetic Switch of the Temperate Bacteriophage TP901-1

DEFF Research Database (Denmark)

Pedersen, Margit; Hammer, Karin

2008-01-01

. The cloned DNA fragment contained the two divergently oriented promoters, P-R and P-L, transcribing the lysogenic and lytic gene clusters; the two promoter-. proximal genes, cl and mor; and the three CI operator sites, O-R, O-L and O-D. We show that mor encodes a protein and that this protein in concert......-D) is enough to maintain a bistable system. The distantly located operator site, 01:), functions as a helper site by increasing binding of CI at O-R and O-L. In the immune state, O-D increases repression of the lytic promoter, P-L. Our results strongly support the model that a hexameric form of Cl binds...... cooperatively to the three operator sites in the immune state forming a CI-DNA loop structure. Finally, we show that in the anti-immune state, repression of the lysogenic promoter is independent of the known CI operator sites but requires the presence of both CI and MOR....

Edukacja żywieniowa rodziny w przypadku występowania otyłości

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Magdalena Pieszko

2013-12-01

Full Text Available Edukacja żywieniowa stanowi ważny element terapii osób z nadwagą i otyłością, będąc niejednokrotnie dopełnie‑ niem dla diety redukcyjnej czy farmakoterapii. Prawidłowo dobrana i realizowana metoda szkolenia powinna speł‑ niać funkcję czynnika mobilizującego i wzmacniającego, dzięki któremu pacjent będzie chętniej modyfikował swój styl życia. Głównym celem edukacji dotyczącej diety jest przekazanie i utrwalenie właściwych postaw żywieniowych, przy czym forma przekazu wiedzy na temat odżywiania skierowana do dzieci nie może być taka sama jak przezna‑ czona dla ich rodziców/opiekunów. Związane jest to z różnicami w rozumieniu i przyswajaniu informacji pomiędzy osobami dorosłymi i dziećmi. Mimo to trzeba pamiętać, że rodzina jest społecznością, której członkowie są ze sobą bardzo związani i mają na siebie duży wpływ – nie można zatem pominąć edukacji, która będzie zachęcała całą rodzinę do wspólnych działań. Zmiana nawyków żywieniowych musi dotyczyć wszystkich członków rodziny, gdyż to rodzice poprzez swoje poglądy, preferencje i zachowania kształtują poglądy, preferencje i zachowania dzieci. Również osoba szczupła powinna dostosować się do nowych zasad dla dobra swoich bliskich. Wzajemna moty‑ wacja może być kluczem do sukcesu. Zmiana stylu życia wiąże się też ze zwiększeniem aktywności fizycznej, która jest nieodzownym elementem terapii pacjentów otyłych. Wzrost aktywności ruchowej może skutecznie skrócić czas leczenia oraz przyczynić się do jego lepszych efektów.

Early Sign Language Experience Goes along with an Increased Cross-Modal Gain for Affective Prosodic Recognition in Congenitally Deaf CI Users

Science.gov (United States)

Fengler, Ineke; Delfau, Pia-Céline; Röder, Brigitte

2018-01-01

It is yet unclear whether congenitally deaf cochlear implant (CD CI) users' visual and multisensory emotion perception is influenced by their history in sign language acquisition. We hypothesized that early-signing CD CI users, relative to late-signing CD CI users and hearing, non-signing controls, show better facial expression recognition and…

AHRQ series on complex intervention systematic reviews-paper 6: PRISMA-CI extension statement and checklist.

Science.gov (United States)

Guise, Jeanne-Marie; Butler, Mary E; Chang, Christine; Viswanathan, Meera; Pigott, Terri; Tugwell, Peter

2017-10-01

Complex interventions are widely used in health systems, public health, education, and communities and are increasingly the subject of systematic reviews. Oversimplification and inconsistencies in reporting about complex interventions can limit the usability of review findings. Although guidance exists to ensure that reports of individual studies and systematic reviews adhere to accepted scientific standards, their design-specific focus leaves important reporting gaps relative to complex interventions in health care. This paper provides a stand-alone extension to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting tool for complex interventions-PRISMA-CI-to help authors, publishers, and readers understand and apply to systematic reviews of complex interventions. PRISMA-CI development followed the Enhancing the QUAlity and Transparency Of health Research Network guidance for extensions and focused on adding or modifying only essential items that are truly unique to complex interventions and are not covered by broader interpretation of current PRISMA guidance. PRISMA-CI provides an important structure and guidance for systematic reviews and meta-analyses for the highly prevalent and dynamic field of complex interventions. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Ustawodawstwo Unii Europejskiej wobec mniejszości narodowych i etnicznych - casus romski

Directory of Open Access Journals (Sweden)

Wojciech Marcin Stankiewicz

2014-12-01

of the Roma minority and replace it with another. That is why the European Union should develop a range of mechanisms and measures that may be accepted by the Roma.   Ustawodawstwo Unii Europejskiej wobec mniejszości narodowych i etnicznych - casus romski Unia Europejska znajduje się dopiero na etapie tworzenia systemu ochrony mniejszości narodowych i etnicznych, jednak niezbędne będzie podjęcie wielu starań, debat oraz działań, w które koniecznie zaangażowane muszą być wszystkie państwa członkowskie. Próby podejmowane przez Parlament Europejski w celu poprawy sytuacji mniejszości narodowych i etnicznych w Unii Europejskiej mogą być odpowiednim impulsem do wstępnych refleksji. Pomimo wielu starań Unii Europejskiej oraz wykorzystania funduszy unijnych sytuacja mniejszości romskiej nie uległa dużej poprawie. Głównymi przyczynami są niedostateczne działania ze strony Unii Europejskiej, korupcja urzędników, a także brak zainteresowania społecznością romską państw członkowskich. Dotychczas podjęte działania nie przyniosły zamierzonych rezultatów, dlatego konieczne jest poświęcenie większej uwagi tej kwestii. Unia Europejska potrzebuje mocnego wsparcia innych instytucji unijnych oraz społeczeństwa obywatelskiego.

Assessing precision, bias and sigma-metrics of 53 measurands of the Alinity ci system.

Science.gov (United States)

Westgard, Sten; Petrides, Victoria; Schneider, Sharon; Berman, Marvin; Herzogenrath, Jörg; Orzechowski, Anthony

2017-12-01

Assay performance is dependent on the accuracy and precision of a given method. These attributes can be combined into an analytical Sigma-metric, providing a simple value for laboratorians to use in evaluating a test method's capability to meet its analytical quality requirements. Sigma-metrics were determined for 37 clinical chemistry assays, 13 immunoassays, and 3 ICT methods on the Alinity ci system. Analytical Performance Specifications were defined for the assays, following a rationale of using CLIA goals first, then Ricos Desirable goals when CLIA did not regulate the method, and then other sources if the Ricos Desirable goal was unrealistic. A precision study was conducted at Abbott on each assay using the Alinity ci system following the CLSI EP05-A2 protocol. Bias was estimated following the CLSI EP09-A3 protocol using samples with concentrations spanning the assay's measuring interval tested in duplicate on the Alinity ci system and ARCHITECT c8000 and i2000 SR systems, where testing was also performed at Abbott. Using the regression model, the %bias was estimated at an important medical decisions point. Then the Sigma-metric was estimated for each assay and was plotted on a method decision chart. The Sigma-metric was calculated using the equation: Sigma-metric=(%TEa-|%bias|)/%CV. The Sigma-metrics and Normalized Method Decision charts demonstrate that a majority of the Alinity assays perform at least at five Sigma or higher, at or near critical medical decision levels. More than 90% of the assays performed at Five and Six Sigma. None performed below Three Sigma. Sigma-metrics plotted on Normalized Method Decision charts provide useful evaluations of performance. The majority of Alinity ci system assays had sigma values >5 and thus laboratories can expect excellent or world class performance. Laboratorians can use these tools as aids in choosing high-quality products, further contributing to the delivery of excellent quality healthcare for patients

Characterisation of the artificial neural network CiPS for cirrus cloud remote sensing with MSG/SEVIRI

Directory of Open Access Journals (Sweden)

J. Strandgren

2017-11-01

characterised with respect to the properties of the investigated cirrus cloud (ice optical thickness and cloud top height. On average CiPS can retrieve the cirrus cloud top height with a relative error around 8 % and no bias and the ice optical thickness with a relative error around 50 % and bias around ±10 % for the most common combinations of cloud top height and ice optical thickness. Similarities with physically based retrieval methods are evident, which implies that even though the retrieval methods differ in the implementation of physics in the model, the retrievals behave similarly due to physical constraints. Finally, we also show that the ANN retrievals have a low sensitivity to radiometric noise in the SEVIRI observations. For optical thickness and ice water path the relative uncertainty due to noise is less than 10 % down to sub-visual cirrus. For the cloud top height retrieval the uncertainty due to noise is around 100 m for all cloud top heights.

Biosorption of C.I. Direct Blue 199 from aqueous solution by nonviable Aspergillus niger

Energy Technology Data Exchange (ETDEWEB)

Xiong Xiaojing, E-mail: xiongxj@xmu.edu.cn [Environmental Science Research Center, State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361005 (China); Meng Xuejiao [Environmental Science Research Center, State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361005 (China); Zheng Tianling [Environmental Science Research Center, State Key Laboratory of Marine Environmental Science, Xiamen University, Xiamen 361005 (China); Key Laboratory of Ministry of Education for Coast and Wetland Ecosystems, School of Life Sciences, Xiamen University, Xiamen 361005 (China)

2010-03-15

The capacity and mechanism with which nonviable Aspergillus niger removed the textile dye, C.I. Direct Blue 199, from aqueous solution was investigated using different parameters, such as initial dye concentration, pH and temperature. In batch experiments, the biosorption capacity increased with decrease in pH, and the maximum dye uptake capacity of the biosorbent was 29.96 mg g{sup -1} at 400 mg L{sup -1} dye concentration and 45 deg. C. The Langmuir and Freundlich models were able to describe the biosorption equilibrium of C.I. Direct Blue 199 onto the fungal biomass. Biosorption followed a pseudo-second order kinetic model with high correlation coefficients (r{sup 2} > 0.99). Thermodynamic studies revealed that the biosorption process was successful, spontaneous and endothermic in nature.

Programa Rede de Residências: Experimentação Arte, Ciência e Tecnologia

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Ana Noronha

2015-12-01

Full Text Available O programa Rede de Residências: Experimentação Arte, Ciência e Tecnologia, que funcionou de 2007 a 2010, resultou de uma parceria entre a Ciência Viva e a Direção-Geral das Artes/Instituto das Artes desenvolvida para criar uma plataforma de trabalho e investigação reunindo artistas e cientistas. Para isto, definiu-se uma rede de instituições científicas de acolhimento, onde 18 artistas desenvolveram projetos de caráter experimental e transdisciplinar com ferramentas e processos específicos dos laboratórios de investigação científica. Esta nota descreve sumariamente as duas edições do programa e dá conta das principais conclusões da sua avaliação.

The Music Experiences and Attitudes Of A First Cohort of Prelingually-Deaf Adolescents and Young Adults CI Recipients

Science.gov (United States)

Gfeller, Kate; Driscoll, Virginia; Smith, Rachel See; Scheperle, Christina

2012-01-01

The purpose of this study was to examine the musical engagement (participation and attitude) of pediatric CI recipients who were implanted during early childhood and who have reached age 15 or older. A questionnaire was administered to a group of 31 prelingually deaf CI users who receive annual follow up services and assessment in a clinical research center. The questionnaire was used to examine involvement in and attitudes toward music in school, the community, and in the home; social affiliation (hearing, Deaf, both) and mode of communication (oral, manual, both) were also examined. Despite the technical limitations of cochlear implants in transmitting pitch, melody, and tone quality, over two thirds of this sample described music as being important or very important in their lives. A high level of past and present familial involvement in music was associated with higher levels of current involvement and importance of music in the lives of adolescent and young adult CI users. Comparisons were noted with data from prior studies of persons with hearing loss who were non-CI users. PMID:23565029

Kriegsbeute-Ausstellung Posen 1917. Propagandowa wystawa dla szerokiej publiczności

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Jakub Skutecki

2014-01-01

Full Text Available W zbiorach ikonograficznych Biblioteki Uniwersyteckiej w Poznaniu znajduje się seria widokówek dokumentujących zorganizowaną w 1917 roku Wystawę Zdobyczy Wojennych (Kriegsbeute-Ausstellung Posen 1917, jedną z serii propagandowych ekspozycji prezentujących sukcesy armii niemieckich na wszystkich frontach wielkiej wojny. W czasie trwania wystawy w pobliżu belgijskiego Passchendaele toczyła się jedna z najkrwawszych bitew, a w Poznaniu – codzienne życie w wojennej rzeczywistości.

The role of CI and learning in an organizational change process-Experiences from a longitudinal study of organizational change

DEFF Research Database (Denmark)

Kofoed, Lise; Gertsen, Frank; Jørgensen, Frances

2002-01-01

these situational barriers, CI, with an emphasis on imbedded learning, was introduced through an action research methodology in the context of an experimental learning lab ("experimentarium"). Contrary to prevailing theory that suggests that CI serves primarily to support and supplement existing radical changes...

O indiciamento de graus de popularização da ciência pela referenciação e pelo discurso relatado

OpenAIRE

Becker, Janaína Pimenta Lemos

2013-01-01

Este trabalho considera que a popularização da ciência corresponde ao fenômeno social de comunicação dos conhecimentos provenientes da ciência à sociedade em geral (HILGARTNER, 1990; CORNELIS, 1998; MYERS, 2003; CALSAMIGLIA; DIJK, 2004) e assume a existência de graus de popularização da ciência postulada por Hilgartner (1990) e por Jacobi (1999, 1990, 1988, 1985 e 1984), de acordo com os quais a comunicação da ciência ocorre em vários contextos, desde os mais restritos e especializados até os...

Photocatalytic degradation of Maxilon C.I. basic dye using CS/CoFe{sub 2}O{sub 4}/GONCs as a heterogeneous photo-Fenton catalyst prepared by gamma irradiation

Energy Technology Data Exchange (ETDEWEB)

Al-Kahtani, Abdullah A. [Chemistry Department, College of Science, King Saud University, P. O. Box 2455, Riyadh 11451 (Saudi Arabia); Pharmaceutical Chemistry Department, College of Pharmacy, Prince Sattam Bin Abdulaziz University, P. O. Box 173, Alkharj 11942 (Saudi Arabia); Abou Taleb, Manal F., E-mail: abutalib_m@yahoo.com [Chemistry Department, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, P. O. Box 173, Alkharj 11942 (Saudi Arabia); Polymer Department National Center for Radiation Research and Technology, Nasr city, Cairo (Egypt)

2016-05-15

Highlights: • CS/CF/GONCs were synthesized via γ-irradiation and used as a heterogeneous photo-Fenton catalyst. • It can degrade Maxilon C.I. basic dye under sunlight irradiation. • A possible degradation pathway of Maxilon C.I. Basic was proposed. • The degradation of Maxilon follows pseudo-first-order kinetics. • The catalyst can be separated by an external magnetic field. • Cyclic degradation tests show the catalyst is highly active, stable and recoverable. - Abstract: CS/CF/GONCs were synthesized via gamma irradiation cross-linking method with the aid of sonication. The nanocomposites exhibited a photo-Fenton catalytic feature for the degradation of Maxilon C.I. basic dye in aqueous medium using sunlight. The effects of pH, H{sub 2}O{sub 2} concentration, and dosage of the catalyst, on the degradation rates of the dyes were examined. The optimal degradation rate was reached with 10 mM H{sub 2}O{sub 2} at pH 9.5. It was verified that the Maxilon C.I. basic dye degradation rate fits a pseudo-first-order kinetics for different initial concentrations of Maxilon C.I. dye. Fourth cyclic tests for Maxilon C.I. degradation showed that the magnetic catalyst was very stable, recoverable, highly active, and easy to separate using an external magnet. Hence, this magnetic catalyst has potential use in organic pollutant removal.

Kształtowanie polskości na łamach „Dziennika Kijowskiego” w latach 1914-1916

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Olena Betlii

2017-12-01

Full Text Available The Shaping of Polish Identity in the “Dziennik Kijowski” in 1914-1916 The First World War was a real catalyst for the shaping of national identities in Eastern Europe. Like all wars, it aroused discussions about the future of peoples caught up in the conflict, especially those who did not possess their own statehood. The Polish nation was among them. How did its political elite respond to the beginning of the Great War in Europe, what was discussed and what topics raised by the Polish newspapers, how Poland’s future and Polish identity was seen and determined at that time? In this article I try to answer these questions by analyzing political, social and literary materials in the Polish daily Dziennik Kijowski published in Kyiv in 1906-1920. Based on archival sources, publications of the Dziennik, analysis of the censuses, and historiography, this publication depicts the “Polish Kyiv”, reflects on various opinions about the newspaper’s editorial policies during the war, and defines the main topics that were elaborated by the Dziennik in 1914-1916 regarding Polish identity issues. During this period the newspaper, as well as the majority of members of the Polish community in Kyiv, was loyal to the Russian authorities. At the same time, the Dziennik Kijowski constantly reminded its readers what the Polish identity meant not only by the mere fact that the newspaper was published in the Pollish language, but also by the Polish matters as the contents of its columns.   Kształtowanie polskości na łamach „Dziennika Kijowskiego” w latach 1914-1916 Pierwsza wojna światowa stała się prawdziwym katalizatorem kształtowania tożsamości narodowych w Europie Wschodniej. Jak każda inna wojna wywoływała ona dyskusje o przyszłości narodów wciągniętych w konflikt, zwłaszcza tych, które nie posiadały swojej państwowości. Do takich narodów wówczas należał również naród polski. W jaki sposób polskie elity polityczne

Alguns efeitos do discurso da ciência na atualidade

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Cristóvão Giovani Burgarelli

2010-08-01

Full Text Available Este artigo pretende discutir um dos desdobramentos da ciência em especial: a tecnociência, considerada aqui como marca da contemporaneidade que dita o imperativo da técnica e de seu aparato como aquilo que, supostamente, a tudo responde, preenche e satisfaz. O meio acadêmico, inserido no contexto cultural atravessado pela lógica tecnocientífica, não está livre de seus efeitos e da dinâmica consumista que tende a considerar o saber como um bem de consumo. Ao contrário, tanto as escolas quanto as universidades aderem a essa lógica e expulsam de seu arcabouço a possibilidade de subjetivação, ou seja, o modo singular de um sujeito se haver, diferentemente, com as marcas que o constituem.

Bioética clínica: ciência e humanidade = Clinical bioethics: science and humanity

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Batista, Cristiano Corrêa

2005-01-01

Full Text Available Objetivo: A medicina pré-moderna tinha por enfoque a harmonia entre o universo e a natureza e tudo era aparentemente possível para os médicos aptos a interpretarem sinais e sintomas. A partir da invenção do estetoscópio inicia-se o processo de investigação do interior dos corpos vivos. Ao longo do tempo, a medicina foi sendo impregnada com a tecnologia e, nos dias atuais, a chamada tecnociência se faz onipresente deixando em segundo plano, ou até mesmo ausente, a interação médico-paciente. Urge a criação de uma nova indústria intelectual com a capacidade de criticar essa nova forma de praticar a medicina embasada principalmente na tecnologia. O objetivo do presente artigo é fazer uma reflexão, por meio da bioética clínica, dessa nova forma de praticar a medicina na tentativa de resgatar o lado humano da ciência médica. Método: Foi realizada uma consulta na base de dados da Medline e LILACS nos últimos dez anos e uma revisão da literatura nacional em torno do tema medicina, bioética, ciência e humanidade. Resultados e conclusão: Nossa conclusão é de a medicina não ser apenas uma ciência, mas também uma arte. Ela exige, em situações particulares, elaborar julgamentos de valor. A Bioética Clínica, surge para guiar caminhos combinando o conhecimento técnico-científico das ciências biomédicas com o conhecimento filosófico. Por meio da Bioética Clínica é possí- vel resgatar os aspectos humanos da arte da medicina

Etyka w zawodzie specjalisty rachunkowości zarządczej w podręcznikach i kształceniu w Polsce

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Irena Sobańska

2016-07-01

Full Text Available Celem artykułu jest poznanie, jak środowisko naukowe rachunkowości wspiera zawód specjalisty ra- chunkowości zarządczej w uświadamianiu wysokich wymagań etycznych oczekiwanych od tego zawo- du. W artykule zostały przedstawione zagadnienia dotyczące etyki w zawodzie specjalisty rachunkowości zarządczej w świetle badań i standardów międzynarodowych oraz wyniki i wnioski z badań treści pol- skich podręczników akademickich i programów kształcenia. Przeprowadzone badania pozwoliły pozy- tywnie zweryfikować postawioną hipotezę, mówiącą, że w procesie kształcenia akademickiego zagad- nienia etyki zawodu specjalisty rachunkowości zarządczej nie są w ogóle lub w minimalnym zakresie objaśniane. Stanowi to wskazówkę do udoskonalenia programów kształcenia w badanym zakresie na uczelniach wyższych w Polsce.

Czytanie Muranowa. Pamięć miejsca / pamięć architekta Komentarz do powojennej twórczości Bohdana Lacherta

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Uchowicz, Katarzyna

2014-12-01

Full Text Available Tekst koncentruje się wokół koncepcji Muranowa Południowego – osiedla / pomnika zrealizowanego na terenie warszawskiego getta przez architekta Bohdana Lacherta. Podejmuje próbę ukazania realizacji w kategoriach mitu artystycznego wykreowanego przez twórcę. Analiza tekstów autora, rekonstrukcja okoliczności towarzyszących budowie oraz szczegóły artystycznej biografii odsłaniają nowe warstwy architektonicznego palimpsestu. Czytelne nawiązania do śmiałych wizji Śródmieścia Macieja Nowickiego oraz zaadaptowanie dla idei osiedla /miejsca pamięci powszechnych w latach czterdziestych eksperymentalnych prób przetwarzania gruzu prowokują pytania o oryginalność koncepcji Muranowa, którego niewątpliwą wartością pozostaje kompozycja przestrzenna wyrastająca z pionierskich poszukiwań Katarzyny Kobro, architektury organicznej Franka Lloyda Wrighta oraz nowego funkcjonalizmu Nowickiego. Historia osiedla to jednocześnie mikrokosmos pierwszych lat odbudowy Warszawy i socrealistycznego chaosu po roku 1949 oraz zapis poszukiwań artystycznej podmiotowości architekta modernisty w nowej rzeczywistości.

Respiratory symptoms and bronchial responsiveness are related to dietary salt intake and urinary potassium excretion in male children.

Science.gov (United States)

Pistelli, R; Forastiere, F; Corbo, G M; Dell'Orco, V; Brancato, G; Agabiti, N; Pizzabiocca, A; Perucci, C A

1993-04-01

To investigate whether dietary salt intake and urinary sodium and potassium levels are related to respiratory symptoms and bronchial responsiveness, a cross-sectional study among 2593 subjects aged 9 to 16 was conducted in four communities of the Latium region (Italy). Questionnaires were administered to the parents, urine samples were collected, lung function, methacholine challenge tests and prick tests were performed. Information about familial and personal dietary salt use and respiratory health was collected from the parents of 2439 (94%) subjects. A total of 2020 methacholine challenge tests and 916 urinary sodium and potassium levels were available for analysis. Personal table salt use was strongly related to cough and phlegm apart from colds (adjusted odds ratios, OR, 1.87, 95% confidence intervals, CI, 1.20-2.90), wheezing apart from colds (OR, 2.19, 95% CI, 1.27-3.77), wheezing with dyspnoea (OR, 1.45, 95% CI, 0.98-2.12) and wheezing after exercise (OR, 2.16, 95% CI, 1.35-3.44). These associations were mainly found in boys. Use of familial table salt and canned food showed no relation to respiratory symptoms. Increased bronchial responsiveness was associated with a higher urinary potassium excretion in boys, but not with urinary sodium. In conclusion, personal table salt use is related to an increased prevalence of bronchial symptoms; an increase in bronchial responsiveness among those with higher potassium excretion also seems to be implied. Although it is difficult to interpret the results of this study in causal terms, the findings might be relevant to the distribution of bronchial symptoms and diseases in the population.

Wartość godziwa i zasady jej ustalania w świetle projektu standardu międzynarodowego „Pomiar wartości godziwej”

OpenAIRE

Frendzel, Maciej

2011-01-01

W opracowaniu analizie poddano uwarunkowania definicyjne pojęcia wartości godziwej w świetle regulacji Międzynarodowych Standardów Sprawozdawczości Finansowej i projektu standardu Pomiar wartości godziwej. Dodatkowo przedstawiono wytyczne odnośnie do ustalania wartości godziwej oraz hierarchii obrazującej subiektywność danych wejściowych. In the paper there is presented the analysis of the concept of fair value under existing International Financial Reporting Standards as well as Exposure...

Globalização: novo paradigma das ciências sociais

OpenAIRE

Ianni,Octavio

1994-01-01

As ciências sociais estão sendo desafiadas a pensar a globalização do mundo. No fim do século XX, quando se anuncia o XXI, elas se defrontam com os dilemas que se abrem com a globalização das coisas, gentes e idéias. Há processos e estruturas sociais, econômicos, políticos, culturais e outros que apenas começam a ser estudados. Além do que é local, nacional e regional, colocam-se problemas novos e fundamentais com a emergência da sociedade global. As fronteiras geográficas e históricas, cultu...

Ocena możliwości implementacji standardów IPSAS do systemu rachunkowości podmiotów sektora publicznego w Polsce

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Aleksandra Szewieczek

2017-09-01

Full Text Available Ocena możliwości implementacji standardów IPSAS do systemu rachunkowości podmiotów sektora publicznego w Polsce In recent years, there has been a noticeable increase in activity in the field of standardization of public sector accounting, which has an international scope and takes the form of the International Public Sector Accounting Standards (IPSAS. It has been planned that the EU Member States, and consequently Poland, will implement obligatory uniform accounting standards in the public sector – EPSAS – which are to be largely based on the content of IPSAS. The purpose of this paper is to assess the possibilities and factors of IPSAS implementation in the accounting system of public finance sector entities in Poland in relation to the currently applicable accounting regulations and the intelligibility criterion for potential users. The assessment was carried out based on a study of the foreign and domestic literature and existing legislation, while for the conclusions, the deductive and synthetic methods were used. The paper demonstrates that despite the relatively long period of operation of IPSAS, their level of implementation into the accounting system of public sector entities in Poland is negligible. The same applies to the works on the European standards, EPSAS, which have been significantly delayed in relation to the original assumptions. Knowledge of international standards is weak, and consequently their dissemination too. In spite of IPSAS implementation problems, there are still a number of reasons for their use. One of the arguments in favor of introducing uniform standards on the European market is the fact that the common market is in operation, and another one is the strong embedding of the need to consolidate the public sector’s international financial data at the central level of the Community. The conducted research confirmed the possibility of implementing IPSAS into Polish public sector entities’ accounting

Wybrane aspekty dotyczące przychodów i kosztóww przedsiębiorstwie postawionymw stan upadłości likwidacyjnej

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Janusz Czerny

2009-06-01

Full Text Available Celem postępowania upadłościowego, które prowadzi do likwidacji przedsiębiorstwa, jest osiągnięcie przychodów ze zbycia jego majątku, co pozwoliłyby na pokrycie kosztów postępowania i zaspokojenia wierzycieli. W upadłości likwidacyjnej przedsiębiorstw mamy do czynienia z dwoma strumieniami przychodów: z przychodami dotyczącymi zbycia przedsiębiorstwa lub jego składników majątku oraz z przychodami związanymi z ewentualnym kontynuowaniem działalności. Przychody ze sprzedaży przedsiębiorstwa powinny być prognozowane głównie na podstawie informacji płynących z systemu rachunkowości, co stanowi tzw. statyczny aspekt upadłości i jest związane z wyceną masy upadłości. Aspekt dynamiczny zaś wiąże się z zakresem i czasem kontynuowanej działalności, o czym decyduje syndyk. Decyzję o zakresie i czasie kontynuowania działalności w przedsiębiorstwie postawionym w stan upadłości likwidacyjnej powinien podjąć syndyk, opierając się na danych generowanych przez system rachunkowości, przy wykorzystaniu narzędzi analizy finansowej. Bardzo istotnym staje się zatem właściwe zarządzanie kosztami procesu upadłości, polegające na ich minimalizacji, co wymaga opracowania przez syndyka budżetu wydatków postępowania upadłościowego oraz przychodów i kosztów kontynuowanej działalności, a następnie szczegółowej kontroli ich wykonania.

Concurrent validity of the Wheeler signs of homosexuality in the Rorschach: P (Ci/Rj).

Science.gov (United States)

Stone, N M; Schneider, R E

1975-12-01

The Rorschach protocols of 43 males consecutively admitted to a university outpatient clinic were scored for frequency of the 20 Wheeler signs of homosexuality. Based on case history data, patients were assigned to homosexual, sex-role disturbed, or normal-control groups. In addition to the traditional group comparison the results were analyzed to yield P (Ci/Rj); that is, the probability of criterion group membership given test indicator. Both the homosexual and sex-role disturbed group displayed significantly more Wheeler signs than normals. Furthermore, given a Wheeler sign score of 15%, .75 of the predicted-homosexual group would be correctly classified compared to a .21 baserate prediction. It was suggested that expressing results as P (Ci/Rj) provides information more relevant to the clinician than is provided by the traditional practice of reporting significant differences between groups.

Life and death of an influential passenger: Wolbachia and the evolution of CI-modifiers by their hosts.

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Arnulf Koehncke

Full Text Available Wolbachia are intracellular bacteria widely distributed among arthropods and nematodes. In many insect species these bacteria induce a cytoplasmic incompatibility (CI between sperm of infected males and eggs of uninfected females. From an evolutionary point of view, CI is puzzling: In order to induce this modification-rescue system, Wolbachia affect sperm of infected males even though Wolbachia are only transmitted maternally. Phylogenetic studies of Wolbachia and hosts show that the bacteria rarely cospeciate with their hosts, indicating that infections are lost in host species. However, the mechanisms leading to Wolbachia loss are not well understood.Using a population genetic model, we investigate the spread of host mutants that enhance or repress Wolbachia action by affecting either bacterial transmission or the level of CI. We show that host mutants that decrease CI-levels in males (e.g. by reducing Wolbachia-density during spermatogenesis spread, even at cost to mutant males. Increase of these mutants can lead to loss of Wolbachia infections, either as a direct consequence of their increase or in a step-wise manner, and we derive analytically a threshold penetrance above which a mutation's spread leads to extinction of Wolbachia. Selection on host modifiers is sexually antagonistic in that, conversely, host mutants that enhance Wolbachia in females are favoured whereas suppressors are not.Our results indicate that Wolbachia is likely to be lost from host populations on long evolutionary time scales due to reduction of CI levels in males. This can occur either by evolution of single host modifiers with large effects or through accumulation of several modifier alleles with small effects on Wolbachia action, even at cost to mutant males and even if infected hosts do not incur fecundity costs. This possibility is consistent with recent findings and may help to explain the apparent short evolutionary persistence times of Wolbachia in many host

Wpływ otyłości na wczesne zmiany miażdżycowe u dzieci z młodzieńczym idiopatycznym zapaleniem stawów

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Barbara Głowińska-Olszewska

2011-08-01

Full Text Available Wstęp: Przewlekłe choroby zapalne u dzieci (w tym młodzieńczeidiopatyczne zapalenie stawów – MIZS zostały uznane za jedenz czynników wysokiego ryzyka rozwoju przedwczesnej chorobyukładu sercowo-naczyniowego. Celem pracy była ocena zależnościmiędzy postacią MIZS, aktywnością choroby, czynnikami ryzykaa wczesnymi zmianami miażdżycowymi u dzieci z MIZS.Materiały i metody: Badaniem objęto 37 dzieci (średnia wieku 12,9roku z MIZS rozpoznanym co najmniej rok wcześniej. Grupę kontrolnąstanowiło 26 zdrowych dzieci (tab. I. U wszystkich badanychoznaczono: wskaźnik masy ciała (body mass index – BMI,ciśnienie tętnicze, lipidogram, stężenie białka C-reaktywnego(C-reactive protein – CRP, fibrynogenu oraz insulinooporność(wskaźnik HOMA – homeostatic model assessment, jak równieżoceniono ultrasonograficznie grubość kompleksu IMT (intimamediathickness tętnic szyjnych wspólnych.Wyniki: U dzieci z MIZS w porównaniu z dziećmi zdrowymi wykazanowyższy wskaźnik SDS-BMI: 0,7 vs –0,02, p = 0,02; stężenieCRP: 0,39 vs 0,06 mg/dl, p = 0,008; fibrynogenu: 356 vs 205 mg/dl,p = 0,003; ciśnienie skurczowe krwi: 120 vs 111 mm Hg, p = 0,002;oraz bardziej nasilone zmiany miażdżycowe (IMT: 0,51 vs 0,43 mm,p = 0,001 (tab. II. U 9 dzieci z MIZS i współistniejącą otyłością/nadwagą (24% dzieci chorych stwierdzono wyższy wskaźnikHOMA: 3,4 w porównaniu z dziećmi zdrowymi – 1,8 (p = 0,04 orazszczupłymi dziećmi z MIZS – 1,7 (p = 0,04, jak również większestężenie triglicerydów i wyższą wartość ciśnienia skurczowegokrwi. Dzieci otyłe miały wyższy wskaźnik IMT: 0,54 vs 0,49 mm(p = 0,001 w porównaniu z dziećmi szczupłymi z MIZS (tab. III,ryc. 1. Analiza korelacji wykazała zależności między IMT a BMI(r = 0,32, p = 0,26, IMT a SDS-BMI (r = 0,38, p = 0,007, IMTa HOMA (r = 0,38, p = 0,035, CRP a BMI (r = 0,33, p = 0,009 orazCRP a ciśnieniem skurczowym krwi (r = 0,41, p = 0,004 (ryc. 2 i 3.Wyst

Experimental and Numerical Investigation of Ethanol/Diethyl Ether Mixtures in a CI Engine

KAUST Repository

Sivasankaralingam, Vedharaj; Raman, Vallinayagam; Jaasim, Mohammed; Alfazazi, Adamu; Lu, Tianfeng; Im, Hong G.; Sarathy, Mani; Dibble, Robert W.

2016-01-01

), were tested in a CI engine. While DE75 and DE50 auto-ignited at an inlet air pressure of 1.5 bar, DE25 failed to auto-ignite even at boosted pressure of 2 bar. The peak in-cylinder pressure for diesel and DE75 were comparable, while DE50 showed reduced

Rodas de ciências na educação infantil: um aprendizado lúdico e prazeroso

OpenAIRE

Celi Rodrigues Chaves Dominguez

2001-01-01

Esta investigação teve o objetivo de identificar as características de ludicidade presentes em rodas de conversa sobre assuntos científicos às quais chamamos de rodas de ciências , realizadas em um grupo de crianças de quatro anos, em uma escola de educação infantil. As rodas de ciências nas quais as crianças conversavam sobre borboletas foram gravadas em áudio e vídeo, no decorrer de aproximadamente seis meses. Constatamos que as rodas apresentavam características lúdicas apenas quando as...

Residuos de plaguicidas organoclorados en Rhizophora mangle y Avicennia germinans en la Ciénaga Grande de Santa Marta, Caribe Colombiano

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Espinosa Luisa F.

1998-06-01

Full Text Available Residues of the organochlorine compounds lindane, heptachlor, aldrin, pp'DDE, pp'DDD y pp'DDT were determined in leaves of two species of mangrove (Rhízophora mangle and Avícennía germínans from the Ciénaga Grande de Santa Marta. Samples were made quarterly (between March and December 1993, at tour stations at the Ciénaga and at one station in Bahía de Chengue (Parque Nacional Natural Tayrona. Measurements were made usinq gas-liquid chromatography. In both ecosystems the two species are accumulating all the six cornpounds analyzed, as well as other indeterminate organochlorines. The greatest concentrations were found for lindane with maximum values of 15,9 ng/g (dry weight. For lindane, heptachlor and aldrin the concentrations were significantly different only between climatic periods. The highest concentrations were obtained for the dry season. The concentration factor by species was calculated and it was determined that the mangroves are accumulating organochlorine compounds in greatest proportion from sedimento.Se determinaron los contenidos de residuos de los plaguicidas organoclorados lindano, heptacloro, aldrin, pp'DDE, pp'DDD Y pp'DDT en hojas de dos especies de mangle (Rhízophora mangle y Avícennía germínans de la Ciénaga Grande de Santa Marta. Se recolectaron muestras trimestralmente (entre marzo y diciembre de 1993 en cuatro estaciones en la Ciénaga y en una estación de la Bahía de Chengue, Parque Nacional Natural Tayrona. Las determinaciones se hicieron por cromatografía gas-líquido. Se encontró que en los dos ecosistemas las dos especies de mangle están acumulando los seis compuestos analizados, además de otros compuestos organoclorados indeterminados. Las mayores concentraciones fueron las de lindano, con valores máximos de 15.9 ng/g (peso seco. Solo se encontraron diferencias significativas entre las épocas climáticas para las concentraciones de lindano, heptacloro y aldrin. Las mayores concentraciones se

Nieswoiste zapalenia jelit a płodność, przebieg ciąży, porodu i karmienie piersią

OpenAIRE

Dorota Szczeblowska; Dariusz Serwin; Andrzej Hebzda; Stanisław Wojtuń; Iwon Grys

2011-01-01

Do nieswoistych zapaleń jelit zaliczamy wrzodziejące zapalenie jelita grubego i chorobę Leśniowskiego-Crohna. Ponieważ szczyt zapadalności na te choroby przypada między 15. a 35. rokiem życia, a więc dotyczy osób w okresie prokreacyjnym, rodzi się szereg pytań i wątpliwości na temat wpływu tych schorzeń oraz ich leczenia na płodność, a także przebieg ciąży, porodu i ewentualne bezpieczeństwo późniejszego karmienia piersią. W opracowaniu zostały przedstawione zasady leczenia nieswo...

Teologia, Ciência da Religião e Filosofia da Religião: definindo suas relações

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Dierken, Jörg

2009-01-01

Full Text Available Trata-se de revisitar o complexo fenômeno da religião, à luz das articulações e diferenciações entre teologia, filosofia da religião e ciência da religião, particularmente no contexto sociocultural da modernidade e suas categorias iluministas de racionalidade, liberdade e ciência, em grandes pensadores tais como Max Weber e Ernst Troeltsch

Mensurações em ciência Measurements in science

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Harley Edson Amaral Bicas

2003-08-01

Full Text Available A natureza da mensuração, terminologias e importância de seus usos em ciência são comentados quanto a sistemas numéricos, representações logarítmicas, unidades (com aplicações a medidas do índice de refração, acuidade visual e ângulos, ordens de grandeza, escalas, sensibilidades, leituras e interpolações, algarismos significativos, precisão e exatidão, fidedignidade e significância (clínica e estatística.The nature of mensurations, terminologies and the importance of their uses are commented regarding numerical systems, logarithmic representations, units (with applications to measurements of the index of refraction, visual acuity and angles, orders of magnitude, scales, sensitivity, instrumental readings and interpolations, significant digits, precision and accuracy, reliability and significance (clinical and statistical.

A cobertura de ciência em três jornais paraenses: um estudo longitudinal

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Vanessa Brasil de Carvalho

Full Text Available Resumo Neste artigo, apresentamos uma proposta metodológica visando realizar um estudo longitudinal que fornecesse um panorama da cobertura de ciência em 130 anos, por três jornais importantes do Estado do Pará: A Província do Pará (1876-2002, Folha do Norte (1896-1974 e O Liberal (1946-atual. Analisamos um período de dois meses a cada dez anos, de 1876 a 2006, em cada jornal selecionado, de maneira que obtivemos um olhar em longo prazo que perpassou pela história dos periódicos e, portanto, por grande parte da história da imprensa no Pará e na Amazônia. Utilizamos análise de conteúdo e análise de frames da Mídia. Nossos dados mostram que houve ênfase na pesquisa em saúde, destaque para a ciência nacional e preocupação em contextualizar os fatos científicos. Controvérsias e incertezas científicas ganharam pouco espaço nos jornais analisados.

Ciência & Saúde Coletiva: scientific production analysis and collaborative research networks.

Science.gov (United States)

Conner, Norma; Provedel, Attilio; Maciel, Ethel Leonor Noia

2017-03-01

The purpose of this metric and descriptive study was to identify the most productive authors and their collaborative research networks from articles published in Ciência & Saúde Coletiva between, 2005, and 2014. Authors meeting the cutoff criteria of at least 10 articles were considered the most productive authors. VOSviewer and Network Workbench technologies were applied for visual representations of collaborative research networks involving the most productive authors in the period. Initial analysis recovered 2511 distinct articles, with 8920 total authors with an average of 3.55 authors per article. Author analysis revealed 6288 distinct authors, 24 of these authors were identified as the most productive. These 24 authors generated 287 articles with an average of 4.31 authors per article, and represented 8 separate collaborative partnerships, the largest of which had 14 authors, indicating a significant degree of collaboration among these authors. This analysis provides a visual representation of networks of knowledge development in public health and demonstrates the usefulness of VOSviewer and Network Workbench technologies in future research.

História da Ciência: objetos, métodos e problemas History of Science: purposes, methods and problems

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Lilian Al-Chueyr Pereira Martins

2005-08-01

Full Text Available O objetivo deste artigo é auxiliar o trabalho de pessoas que estão se iniciando na pesquisa de História da Ciência, especialmente em relação a um determinado tipo de trabalho a que nos dedicamos. Este tratará da escolha de um tema adequado de pesquisa, dos tipos de fontes encontradas em História da Ciência e de alguns problemas encontrados em trabalhos de História da Ciência. Este estudo levou à conclusão de que só se apreende a fazer pesquisa em História da Ciência a partir da prática e que um bom historiador da ciência se constrói a longo prazo.The aim of this paper is to help people who are starting History of Science research, especially concerning a definite kind of work to which we dedicate ourselves. It deals with the choice of a suitable research subject, the kinds of sources in History of Science, as well as some problems which may be found in the works on History of Science. This study leads to the conclusion that beginners learn how to do History of Science research through the praxis and that a person becomes a good historian of science in the long term.

Entre "artes" e "ciências": a noção de performance e drama no campo das ciências socias

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Rubens Alves da Silva

2005-12-01

Full Text Available Propõe-se neste artigo desenvolver uma reflexão teórica que está relacionada com as preocupações e propostas da área de estudos antropológicos das formas expressivas, focalizando, centralmente, a noção de performance e drama no campo das ciências sociais. Nesse sentido é que se busca, no momento, dialogar com os autores considerados representantes principais da discussão teórica em torno da noção de performance, drama e ritual no campo antropológico: Victor Turner, Clifford Geertz, Michael Taussig, Richard Schechner, John Dawsey - entre outros.This article attempts to develop a theoretical reflection on the aims and proposals in the area of the anthropological studies about the expressive forms, dealing with the concept of performance and drama in the social sciences. Taking this into consideration, this work intends to discuss the ideas of the most important authors in the theoretical debate concerning the concept of performance, drama and ritual in the anthropological field: Victor Turner, Clifford Geertz, Michael Taussig, Richard Schechner, John Dawsey - and others.

Ocena częstości występowania bólu głowy oraz objawów mu towarzyszących = Assessment of the frequency of the occurrence of headaches and associated with them symptoms

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Katarzyna Kożuch

2016-05-01

4Katedra i Klinika Nefrologii, UM w Lublinie   Uniwersytet Medyczny w Lublinie ul. W. Chodźki 1, 20-093 Lublin e-mail: piotr7176@gmail.com     Streszczenie Celem pracy była ocena częstości występowania bólu głowy oraz objawów mu towarzyszących. W badaniu oceniono również poziom natężenia bólu oraz okoliczności pojawienia się dolegliwości bólowych oraz czas ich trwania i charakter bólu. Badaniem objęto 103 osób. Kobiety stanowiły 56,9% respondentów, natomiast mężczyźni 43,1%. Wiek ankietowanych zawierał się pomiędzy 18 a 75 lat.  Badanie przeprowadzono w okresie od stycznia do marca 2016 roku metodą wywiadu standaryzowanego. Narzędziem użytym do zebrania danych, był autorski, anonimowy kwestionariusz. Kwestionariusz zawierał 43 pytania z możliwością jednokrotnego wyboru w tym trzy pytania z możliwością wielokrotnego wyboru. Przeprowadzono analizę statystyczną z wykorzystaniem testu chi- kwadrat. Wszystkie wartości w których p<0,05 uznano za istotne statystycznie. Wszyscy ankietowani skarżyli się na dolegliwości bólowe głowy. Ankietowani najczęściej (36,5% wskazywali odpowiedź o występowaniu bólu głowy kilka razy w miesiącu. 39,4% ankietowanych odczuwa dolegliwości bólowe głowy o różnej porze dnia. Na pytanie dotyczące długości trwania dolegliwości bólowych ankietowani najczęściej (36,4% wskazywali, że ból głowy trwa zazwyczaj około 1 godzinę. Respondenci istotnie statystycznie (p<0,05 częściej potrafili określić lokalizację bólu głowy. Ankietowani z podobną częstością wskazywali ból w okolicy skroniowej (27,7% oraz w okolicy potylicznej (24,8%. Mężczyźni istotnie statystycznie (p<0,05 częściej odczuwają silniejszy ból głowy w porównaniu do kobiet. Najczęstszym objawem towarzyszącym dolegliwościom bólowym głowy była zmiana nastroju (66,3%, p<0,05. Blisko jedna trzecia ankietowanych odczuwa podczas napadu bólu głowy sztywność karku (28,7%, na nudności i wymioty

O livro didático de ciências: problemas e soluções Science texbooks: problems and solutions

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Jorge Megid Neto

2003-01-01

Full Text Available Analisa a temática do livro didático para o ensino de Ciências no Brasil e apresenta alternativas a este recurso, tendo em conta: as atuais características dos manuais didáticos; os usos dos compêndios escolares pelos professores; as novas propostas curriculares para o ensino de Ciências; os resultados da pesquisa educacional sobre ensino de Ciências e sobre os livros didáticos no Brasil.This article analyses the theme of didactic books for Science teaching in Brazil and it presents alternatives to this resource. The main points analyzed are: the characteristics of didactic books; the use by teachers of school texts; the new curricular proposals for science teaching; the results of educational research about science teaching and about textbooks in Brazil.

A evolução da ciência da informação a partir de conceitos-sinônimos empregados na obra ciência da informação ou informática?

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Marco Donizete Paulino da Silva

2012-01-01

Full Text Available Este trabalho foi desenvolvido a partir de uma análise bibliográfica sobre artigos que compõem o livro Informática ou Ciência da Informação?, organizado por Hagar Espanha Gomes, em 1980. Estrutura-se como projeto de revisão histórica em que se narra as impressões estabelecidas durante leitura da obra, evidenciando os termos considerados relevantes e coletando-os para análise posterior do contexto em que estes foram empregados. Deduziu-se, dessa análise, a forma como a Ciência da Informação foi sendo reconhecida como disciplina independente da Biblioteconomia, assim como os níveis de elaboração de cada época a partir dos termos empregados para designá-la.

History of Met Lab Section C-I, May 1943 to April 1944

International Nuclear Information System (INIS)

Seaborg, G.T.

1978-05-01

This is part of a history of the research work of Seaborg and associates in the University of Chicago Metallurgical Laboratory, Chemistry Section C-I. The work was concerned with the development of chemical procedures for the extraction of plutonium, for the purification of plutonium, and for research on the isotopes of other heavy elements including other transuranium elements. The style of the history is that of a diary with footnotes giving additional information

History of Met Lab Section C-I, May 1943 to April 1944

Energy Technology Data Exchange (ETDEWEB)

Seaborg, G.T.

1978-05-01

This is part of a history of the research work of Seaborg and associates in the University of Chicago Metallurgical Laboratory, Chemistry Section C-I. The work was concerned with the development of chemical procedures for the extraction of plutonium, for the purification of plutonium, and for research on the isotopes of other heavy elements including other transuranium elements. The style of the history is that of a diary with footnotes giving additional information. (DLC)

Potrzeby i możliwości rehabilitacji chorych na stwardnienie rozsiane w Polsce

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Andrzej Potemkowski

2015-08-01

Full Text Available Specyfika stwardnienia rozsianego sprawia, że rehabilitacja pacjentów cierpiących na tę chorobę jest jednym z najtrudniejszych zadań rehabilitacji neurologicznej. Liczne objawy stwardnienia rozsianego znacznie obniżają jakość życia około 40 000 chorych żyjących w Polsce. Choć rehabilitacja nie zmniejsza istotnie częstości rzutów ani nie zatrzymuje progresji choroby, to – jeśli jest odpowiednio, nowocześnie prowadzona – poprawia nie tylko obiektywne wskaźniki, lecz także subiektywne samopoczucie i samoocenę, a w rezultacie daje możliwość wytworzenia pozytywnego obrazu siebie. Potrzeby polskich chorych są duże, ale dostępność rehabilitacji (zarówno ambulatoryjnej, jak i  stacjonarnej jest wysoce niesatysfakcjonująca. W związku z tym powinno się optymalizować jakość rehabilitacji prowadzonej przez chorych samodzielnie, w warunkach domowych. Duże znaczenie mają zatem wiedza pacjenta na temat wpływu rehabilitacji na chorobę i możliwych form leczniczych, jak również świadomość skutków zaniechania tej formy leczenia. Stwardnienie rozsiane, niezależnie od postaci, prowadzi do niepełnosprawności i obniżenia jakości życia, a to ogranicza samodzielność, niesie ze sobą ryzyko utraty pracy, utrudnia samoobsługę i swobodę w zakresie aktywności dnia codziennego. Istotna staje się rola rehabilitacyjnych zespołów terapeutycznych (specjaliści neurologii i rehabilitacji plus fizjoterapeuta, które powinny istnieć w każdej poradni diagnostyki i leczenia stwardnienia rozsianego. Ustalenie przez taki zespół ubytków funkcji oraz określenie celów i planu postępowania pozwoliłyby na zmniejszanie skutków postępu choroby.

KONDENSACJA W PRZEGRODZIE ŚCIENNEJ Z KOMPOZYTU WAPIENNO-KONOPNEGO – OCENA MOŻLIWOŚCI WYSTĄPIENIA

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Przemysław BRZYSKI

Full Text Available Obecność składników organicznych w materiałach budowlanych, decyduje o ich wrażliwości na wilgoć, a dłuższej perspektywie na ich korozję biologiczną, jeśli nie zostaną odpowiednio zabezpieczone przed czynnikami atmosferycznymi. Przegrody powinno się projektować zwracając uwagę na ryzyko wystąpienia powierzchniowej oraz międzywarstwowej kondensacji pary wodnej. W artykule przedstawiono analizę przegrody ściennej, wykonanej z kompozytu wapienno-konopnego. Założono grubość ściany 40 cm oraz po 2 cm tynku po obu stronach. Kompozyt składa się z modyfikowanego spoiwa wapiennego oraz paździerzy konopnych pozyskanych z konopi przemysłowych. Parametry materiału, potrzebne do analizy (współczynnik przewodności cieplnej oraz paroprzepuszczalność wyznaczono doświadczalnie w badaniach własnych. W części analitycznej artykułu przedstawiono obliczenia temperatury powierzchni koniecznej do uniknięcia krytycznej wilgotności powierzchni wewnętrznej ściany oraz określono możliwość wystąpienia kondensacji międzywarstwowej w analizowanej ścianie. Obliczenia wykonano zgodnie z normą PN-EN 13788. Przyjęto warunki brzegowe dla lokalizacji Lublin. Miesiącem krytycznym, w którym przegroda jest najbardziej narażona na kondensację jest styczeń. Z uwagi na dobre parametry termoizolacyjne przegrody, jej budowę ryzyko rozwoju pleśni na wewnętrznej powierzchni ściany nie występuje. Kondensacja wewnętrzna występuje w przegrodzie w okresie grudzień – luty. Natomiast już w marcu zgromadzony kondensat ulega całkowitemu odparowaniu. Przegroda odpowiedniej grubości, wykonana z kompozytu wapienno-konopnego, z uwagi na swoją wysoką paroprzepuszczalność oraz niskie przewodnictwo cieplne nie jest narażona na długotrwałe i niszczące oddziaływanie skraplającej się wewnątrz pary wodnej.

Construindo pontes entre ciência, política e práticas em saúde coletiva

OpenAIRE

Bosi, Maria Lúcia Magalhães; Gastaldo, Denise

2011-01-01

O artigo analisa elementos nucleares no debate nacional e internacional acerca da necessária integração entre ciência, política e práticas em Saúde Coletiva e apresenta subsídios para essa integração. São assinalados alguns obstáculos situados tanto no plano conceitual como aqueles presentes nas relações que se processam em outras esferas e se interpõem à pretendida integração. Dentre os elementos assinalados, evidencia-se que ciência, política e o âmbito das práticas no setor não são campos ...

Trudności diagnostyczne i terapeutyczne w przypadku ziarniniaka grzybiastego rozpoznanego wstępnie jako actinic reticuloid

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Małgorzata Sokołowska-Wojdyło

2010-07-01

Full Text Available Wprowadzenie: Ziarniniak grzybiasty (mycosis fungoides – MF to chłoniako niskiej złośliwości, wywodzący się z obwodowych komórek T,pierwotnie zajmujący skórę. Cel pracy: Przedstawienie trudności diagnostycznych i terapeutycznychw MF. Opis przypadku: Przedstawiono przypadek dotyczący 72-letniejpacjentki z MF, objętej opieką przez Klinikę od października 2007 dowrześnia 2009 roku. Zmiany skórne miały cechy melanoerytrodermii,a obraz histopatologiczny wycinków ze zmian nie upoważniał do rozpoznaniarozrostu złośliwego. Początkowo rozpoznawano osutkępolekową oraz actinic reticuloid. Rozpoznanie MF ustalono dopiero po19 miesiącach obserwacji. Na skórze chorej wystąpiły zmiany rumieniowo-naciekowe, które w badaniu histopatologicznym miały cechyMF. Dwa miesiące później chora zmarła, mimo leczenia cytostatycznegoi naświetlań szybkimi elektronami. Wnioski: Przedstawiony przypadek potwierdza trudności diagnostycznewynikające z podobieństwa wczesnych okresów chłoniaka dodermatoz o podłożu zapalnym. Wyjątkowo niepomyślny przebieg choroby– pacjentka zmarła po 2 latach od momentu ustalenia rozpoznania– uzmysławia także ograniczenia możliwości terapeutycznych,szczególnie w zaawansowanych stadiach MF.

40 CFR 63.6602 - What emission limitations must I meet if I own or operate an existing stationary CI RICE with a...

Science.gov (United States)

2010-07-01

... if I own or operate an existing stationary CI RICE with a site rating of equal to or less than 500....6602 What emission limitations must I meet if I own or operate an existing stationary CI RICE with a... own or operate an existing stationary CI RICE with a site rating of equal to or less than 500 brake HP...

Directional sensitivity of differential pressure sensors of gas velocity used in manual gravimetric measurements of dust emissions from stationary sources / Czułość kierunkowa różnicowo-ciśnieniowych czujników prędkości gazu stosowanych w manualnych pomiarach grawimetrycznych emisji zanieczyszczeń pyłowych ze źródeł stacjonarnych

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Szulikowski Jerzy

2015-09-01

Full Text Available Na potrzeby określania emisji zanieczyszczeń pyłowych do atmosfery z przemysłowych instalacji technologicznych często wykonywane są manualne pomiary rozkładu prędkości gazu w kanałach instalacji gazów odlotowych przy pomocy układów z różnicowo-ciśnieniowymi czujnikami prędkości. Celem jest ustalenie profi lu prędkości osiowej. Przepływy w przekrojach pomiarowych nie zawsze są współosiowe z biegiem kanału; cechują się różnymi kierunkami wektora prędkości w różnych punktach pomiarowych. Ustalanie rzeczywistych kierunków wektorów prędkości lokalnych, dające gwarancję dokładnego obliczenia prędkości osiowych, często nie jest możliwe z technicznego punktu widzenia i pomiar prędkości prowadzi się przy ustawieniu głowicy czujnika równoległym w stosunku do osi i ścian kanału. Wtedy wiedza o czułości kierunkowej zastosowanego czujnika prędkości pozwala albo na wyeliminowanie błędu pomiaru prędkości osiowej, albo na uwzględnienie go poprzez niepewność tego pomiaru. Dla specyfi cznych sytuacji dwuwymiarowej zmienności kierunku wektora prędkości wyznaczono charakterystyki czułości kierunkowej i w konsekwencji charakterystyki błędu trzech przyjętych do badań czujników: pyłowej sondy zerowej o funkcji anemometrycznej jako elementu pyłomierza grawimetrycznego i porównawczo - dwóch powszechnie stosowanych rurek spiętrzających: typu S i L.

Biografia nieobecna. Wokół życia i twórczości Ireneusza Plater-Zyberka

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Robert Zawisza

2014-12-01

Full Text Available An Absent Biography. About the life and work of Ireneusz Plater-Zyberk Ireneusz Plater-Zyberk (1896–1946, was a writer and a film producer, adventurer and gallant. His life is an incredible story of the disabled individual who succeeded in an amazing career. Plater-Zyberk was born in a wealthy landowning family who lived at the estate of Vabole in Latvia. He was born without hands and at that time, due to his disability, was classified as "margins of society." Thanks to perseverance and commitment of his mother, he graduated as an extern student from high school in Warsaw, Poland. His career  includes Life without Hands, memories,  and two novels. He was a co-author of first movie in Poland with stunt effects Dead Node (1927, which unfortunately wasn’t preserved. Also, he was recognized as a documentary creator as well as an initiator of film production regulations.   Biografia nieobecna. Wokół życia i twórczości Ireneusza Plater-Zyberka Ireneusz Plater-Zyberk (1896 lub 1897–1946 był literatem i twórcą filmowym, nieco awanturnikiem i bawidamkiem. Jego postać to niezwykły przykład niepełnosprawnego, który osiągnął w dwudziestoleciu międzywojennym znaczącą karierę. Ireneusz Plater-Zyberk pochodził z zamożnej rodziny ziemiańskiej, zamieszkałej w majątku Wabol na Łotwie. Urodził się bez rąk i w ówczesnej rzeczywistości miał pozostać na marginesie społeczeństwa. Dzięki wytrwałości matki udało mu się ukończyć jako ekstern gimnazjum w Warszawie. W swoim dorobku ma wspomnienia Życie bez rąk oraz dwie powieści. Ważną rolę odegrał Plater jako scenarzysta i reżyser, był m.in. współtwórcą pierwszego polskiego filmu z efektami kaskaderskimi „Martwy węzeł” (1927. Miał on również ogromne zasługi jako twórca filmów dokumentalnych i jednocześnie inspirator zmian w prawodawstwie dotyczącym produkcji filmowej. Tłem jego twórczości pisarskiej jest burzliwe i pełne przygód �

Masculinidade e ciúme na perspectiva da teoria da sedução generalizada

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Paulo Carvalho Ribeiro

2012-09-01

Full Text Available Partindo das contribuições freudianas sobre as relações do ciúme com a projeção e a homossexualidade, propõe-se no presente artigo uma retomada do papel do masoquismo primário e da identificação feminina como elementos definidores do ciúme masculino patológico. As condições originárias de constituição do psiquismo, vistas sob o ângulo da Teoria da Sedução Generalizada, proposta por Jean Laplanche, são relacionadas tanto ao masoquismo primário quanto à identificação feminina. A situação assimétrica entre o adulto, portador de uma sexualidade inconsciente, e a criança, destituída de recursos psíquicos para lidar com as mensagens sexuais do adulto, caracteriza, segundo esse autor, a situação antropológica fundamental.

Ciência da Informação, ciência e revolução científica:breve histórico e reflexõesCiencia de la Información, ciencia y revolución científica: breve histórico y reflexiones

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Ednéa Zandonadi Brambila

2006-02-01

Full Text Available O artigo traz uma breve introdução histórica da construção do saber e do nascimento da ciência, percorrendo os caminhos desde os primórdios da humanidade quando o homem se descobriu até os dias atuais, com a evolução constante da ciência, seja investigando, testando, experimentando e até refutando teorias. Aborda questões da ciência e da revolução científica, do pensamento científico moderno, da construção do saber racional a partir da observação da realidade (empirismo e da experimentação para então chegar ao surgimento da Ciência da Informação, cujo nascimento para alguns autores tem origem no Séc. XIX com Paul Otlet e Henri La Fontaine, pioneiros da Documentação. Discute conceitos numa perspectiva histórica, concluindo ser a Ciência da Informação uma nova disciplina, uma nova forma do conhecimento que se inter-relaciona com outras disciplinas, tendo sofrido mudanças consideráveis desde a sua concepção, repensando seu objeto de estudo e reforçando a idéia de que a informação é o resultado de um processo cognitivo humano.

Assessment of Electromagnetic Interference with Active Cardiovascular Implantable Electronic Devices (CIEDs) Caused by the Qi A13 Design Wireless Charging Board.

Science.gov (United States)

Seckler, Tobias; Jagielski, Kai; Stunder, Dominik

2015-05-27

Electromagnetic interference is a concern for people wearing cardiovascular implantable electronic devices (CIEDs). The aim of this study was to assess the electromagnetic compatibility between CIEDs and the magnetic field of a common wireless charging technology. To do so the voltage induced in CIEDs by Qi A13 design magnetic fields were measured and compared with the performance limits set by ISO 14117. In order to carry this out a measuring circuit was developed which can be connected with unipolar or bipolar pacemaker leads. The measuring system was positioned at the four most common implantation sites in a torso phantom filled with physiological saline solution. The phantom was exposed by using Helmholtz coils from 5 µT to 27 µT with 111 kHz sine‑bursts or by using a Qi A13 design wireless charging board (Qi‑A13‑Board) in two operating modes "power transfer" and "pinging". With the Helmholtz coils the lowest magnetic flux density at which the performance limit was exceeded is 11 µT. With the Qi‑A13‑Board in power transfer mode 10.8% and in pinging mode 45.7% (2.2% at 10 cm distance) of the performance limit were reached at maximum. In neither of the scrutinized cases, did the voltage induced by the Qi‑A13‑Board exceed the performance limits.

Kinetic-energy matrix elements for atomic Hylleraas-CI wave functions

Energy Technology Data Exchange (ETDEWEB)

Harris, Frank E., E-mail: harris@qtp.ufl.edu [Department of Physics, University of Utah, Salt Lake City, Utah 84112, USA and Quantum Theory Project, University of Florida, P.O. Box 118435, Gainesville, Florida 32611 (United States)

2016-05-28

Hylleraas-CI is a superposition-of-configurations method in which each configuration is constructed from a Slater-type orbital (STO) product to which is appended (linearly) at most one interelectron distance r{sub ij}. Computations of the kinetic energy for atoms by this method have been difficult due to the lack of formulas expressing these matrix elements for general angular momentum in terms of overlap and potential-energy integrals. It is shown here that a strategic application of angular-momentum theory, including the use of vector spherical harmonics, enables the reduction of all atomic kinetic-energy integrals to overlap and potential-energy matrix elements. The new formulas are validated by showing that they yield correct results for a large number of integrals published by other investigators.

Udvikling af dialogisk kompetence hos børn med CI

DEFF Research Database (Denmark)

Dammeyer, Jesper Herup; Carstensen, Susanne; Karlshøj, Bente

2011-01-01

Der er relativ god viden om børn med CI’s sproglige udvikling, hvad angår sproglyde og ord. Derimod er der i den internationale forskning kun beskrevet meget lidt om den del af den sproglige udvikling, som ligger ud over sætningsniveauet. Denne artikel beskriver nogle af de resultater, der er...... fremkommet ved et fire år langt følgestudie af tre førskolebørn med CI. Børnenes sproglige udvikling er observeret og analyseret i forhold til dialogiske kompetencer. Resultaterne peger på, at børnene udvikler gode talesproglige kompetencer i løbet af den fireårige periode, men at børnene har brug for støtte...

A biblioteca do ensino intuitivo e o ensino de ciências na escola primária brasileira: 1880-1900

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Karl Michael Lorenz

2007-06-01

Full Text Available O trabalho discute a importância do ensino de Ciências na escola primária brasileira no último quartel do século XIX, tendo como foco de análise os livros didáticos de Ciências que surgiram depois da reforma educacional de 1878, do Ministro Carlos Leôncio de Carvalho, e o Parecer de 1883, de Rui Barbosa. O trabalho relata primeiro as idéias prevalecentes no exterior e debatidas no  Brasil sobre o papel e a maneira de ensinar as ciências na escola primária. Segue com uma discussão de livros-didáticos de Ciências Naturais divulgados no Brasil, e, particularmente, da coletânea de livros intitulada Biblioteca do Ensino Intuitivo — As Sciencias Naturaes. Os livros, destinados  para o ensino primário, foram escritos por eminentes autores ingleses e publicados na Inglaterra e nos Estados Unidos sob o título Science Primers. A coletânea foi traduzida para o português e adaptada para o ensino brasileiro na década de 1880 e 1890.

WERYFIKACJA MOŻLIWOŚCI ZASTOSOWANIA WSKAŹNIKA ITS DO OCENY STANU TROFICZNEGO ZBIORNIKA DOBCZYCKIEGO

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Elena NEVEROVA-DZIOPAK

2016-05-01

Full Text Available W ostatnich latach problem eutrofizacji stał się powszechny nie tylko w wodach stojących ale także w płynących. Budzi on spore zainteresowanie zwłaszcza gdy zaczyna dotyczyć wód przeznaczonych do zaopatrzenia ludzi w wodę do spożycia. Zbiornik Dobczycki o którym traktuje artykuł jest właśnie takim rezerwuarem. Tu ujmowana jest woda dla mieszkańców Krakowa. W literaturze spotyka się stwierdzenia, że wody zbiornika zawsze były podatne na eutrofizację ze względu na ładunki biogenów które są wnoszone do niego przez Rabę. Problem oceny stopnia eutrofizacji Zbiornika Dobczyckiego został więc podjęty nie tyle ze względów poznawczych, co utylitarnych. Wymagał rzetelnej i szczegółowej analizy danych pomiarowych pochodzących z monitoringu. Do oceny zjawiska eutrofizacji wykorzystano integralny wskaźnik troficzności ITS. Jest on jednym z coraz powszechniej stosowanych obecnie zagregowanych wskaźników. Dostrzeżono że graniczne wartości pojedynczych parametrów niekoniecznie odzwierciedlają stan trofii i uprawniają do wnioskowania o zjawisku eutrofizacji. Zastosowanie wskaźnika ITS wiąże się z wykorzystaniem parametrów takich jak pH i nasycenie wody tlenem, które odzwierciedlają bilans gazowy w wodach, zmieniający się wraz ze zmianą bilansu procesów produkcji i rozkładu materii organicznej. Nie wymaga on więc szczegółowych oznaczeń monitoringowych, przez co może być wykorzystywany jako uniwersalny sposób oceny trofii. W artykule uzasadniono wybór wskaźnika ITS jako metody oceny trofii na podstawie analizy statystycznej danych monitoringu Zbiornika pochodzących z okresu wieloletniego. Uwiarygodniło to ocenę i pozwoliło dostrzec pewne prawidłowości procesu oraz jego dynamikę. Na jej podstawie możliwa jest prognoza prawdopodobnego scenariusza dalszego rozwoju zjawiska. Utrzymujący się w minionych 15 latach stan pograniczny zaawansowanej mezotrofii/eutrofii przy jednoczesnej dobrej

Determinants Of European Banks' Capital Adequacy / Determinanty Adekwatności Kapitałowej Banków Europejskich

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Klepczarek Emilia

2015-12-01

Full Text Available W artykule przedstawiono analizę czynników wpływających na poziom wskaźnika CET 1 ratio, będącego miarą relacji pomiędzy kapitałem podstawowym banku a aktywami ważonymi ryzykiem. Badaniu poddano próbę losowo wybraną z grupy banków uczestniczących w tzw. stress-testach przeprowadzonych przez władze Europejskiego Banku Centralnego. EBC przeprowadził testy warunków skrajnych oceniając m.in. poziom współczynnika CET1 obliczanego według regulacji wynikających z III Reżimu Bazylejskiego. Wyniki potwierdzają hipotezę o wpływie wielkości banku i wskaźników ryzyka (aktywa ważone ryzykiem do aktywów ogółem; udział pożyczek w aktywach ogółem na poziom adekwatności kapitałowej. Potwierdzono również silny wpływ konkurencji, a także ujemną korelację między wskaźnikiem CET1 i udziałem depozytów w zobowiązaniach kapitałowych, którą można uzasadnić istnieniem systemu gwarantowania depozytów. W końcowej części artykułu przedstawiono możliwe słabości przeprowadzonych badań, wynikające z nich ograniczenia wnioskowania oraz koncepcje ewentualnych dalszych analiz przedmiotowego obszaru tematycznego.

História das ciências - contribuição à cidadania no Ensino Fundamental I : propostas didáticas

OpenAIRE

Silva, Michele Alves da

2014-01-01

Orientadora: Profª Drª Márcia Helena Alvim Dissertação (mestrado) - Universidade Federal do ABC, Programa De Pós-Graduação em Ensino, História, Filosofia das Ciências e Matemática, 2014. Este trabalho tem como objetivo principal salientar as potencialidades de inclusão da História das Ciências no ensino de Ciências Naturais nas séries iniciais da Educação Básica. A criança traz para o ambiente escolar seu conhecimento prévio sobre a natureza já nas primeiras séries de escolarização. Alg...

Excess maternal salt intake produces sex-specific hypertension in offspring: putative roles for kidney and gastrointestinal sodium handling.

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Clint Gray

Full Text Available Hypertension is common and contributes, via cardiovascular disease, towards a large proportion of adult deaths in the Western World. High salt intake leads to high blood pressure, even when occurring prior to birth - a mechanism purported to reside in altered kidney development and later function. Using a combination of in vitro and in vivo approaches we tested whether increased maternal salt intake influences fetal kidney development to render the adult individual more susceptible to salt retention and hypertension. We found that salt-loaded pregnant rat dams were hypernatraemic at day 20 gestation (147±5 vs. 128±5 mmoles/L. Increased extracellular salt impeded murine kidney development in vitro, but had little effect in vivo. Kidneys of the adult offspring had few structural or functional abnormalities, but male and female offspring were hypernatraemic (166±4 vs. 149±2 mmoles/L, with a marked increase in plasma corticosterone (e.g. male offspring; 11.9 [9.3-14.8] vs. 2.8 [2.0-8.3] nmol/L median [IQR]. Furthermore, adult male, but not female, offspring had higher mean arterial blood pressure (effect size, +16 [9-21] mm Hg; mean [95% C.I.]. With no clear indication that the kidneys of salt-exposed offspring retained more sodium per se, we conducted a preliminary investigation of their gastrointestinal electrolyte handling and found increased expression of proximal colon solute carrier family 9 (sodium/hydrogen exchanger, member 3 (SLC9A3 together with altered faecal characteristics and electrolyte handling, relative to control offspring. On the basis of these data we suggest that excess salt exposure, via maternal diet, at a vulnerable period of brain and gut development in the rat neonate lays the foundation for sustained increases in blood pressure later in life. Hence, our evidence further supports the argument that excess dietary salt should be avoided per se, particularly in the range of foods consumed by physiologically immature young.

Prevalence and correlates of human herpesvirus 8 infection among Peruvian men who have sex with men.

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Guanira, Juan V; Casper, Corey; Lama, Javier R; Morrow, Rhoda; Montano, Silvia M; Caballero, Patricia; Suárez, Luis; Whittington, William L H; Wald, Anna; Sanchez, Jorge; Celum, Connie

2008-12-15

Infection with human herpesvirus 8 (HHV-8) is common among men who have sex with men (MSM) in North America and Europe and is also found to be endemic in some regions of South America. Little is known about HHV-8 prevalence and its correlates among MSM in the Andean region. We assessed HHV-8 seroprevalence among 497 MSM recruited for the 2002 Peruvian HIV sentinel surveillance program using a combined HHV-8 enzyme immunoassay and immunofluorescence assay algorithm. Logistic regression analysis was used to estimate odds ratios (ORs) and their 95% confidence intervals (CIs) to determine the association between selected covariates and HHV-8 seropositivity. One hundred thirty-one (66.5%, 95% CI 63.1% to 69.9%) of 197 HIV-infected and 80 (26.7%, 95% CI 24.4% to 29.0%) of 300 HIV-uninfected MSM had serologic evidence of HHV-8 infection. Factors independently associated with HHV-8 infection were education<12 years (OR 1.7, 95% CI 1.1 to 2.7), anal receptive sex with the last partner (OR 2.0, 95% CI 1.2 to 3.3), self-reported sexually transmitted infection symptoms during the last year (OR 1.9, 95% CI 1.2 to 3.0), coinfection with HIV (OR 4.2, 95% CI 2.8 to 6.4) and chronic hepatitis B (OR 4.9, 95% CI 1.5 to 15.8). MSM with long-standing HIV infection were more likely to have serologic evidence of HHV-8 infection when compared with men with recently acquired HIV (OR 3.8, 95% CI 1.7 to 9.1). HHV-8 infection is common among both HIV-infected and HIV-negative MSM in Lima, Peru. HHV-8 seropositivity is correlated with anal receptive sex, self-reported sexually transmitted infection symptoms, and HIV infection among these MSM and thus seems to be sexually transmitted. HHV-8 infection seems to be acquired after HIV infection, suggesting that future studies should evaluate the mode of HHV-8 transmission and prevention strategies among HIV-uninfected MSM.

Effect of 30 mCi radioiodine on multinodular goiter previously treated with recombinant human thyroid-stimulating hormone

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Paz-Filho, G.J.; Mesa-Junior, C.O.; Boguszewski, C.L.; Carvalho, G.A.; Graf, H. [Universidade Federal do Parana (UFPR), Curitiba, PR (Brazil). Hospital de Clinicas. Servico de Endocrinologia e Metabologia; Olandoski, M. [Pontificia Univ. Catolica do Parana, Curitiba, PR (Brazil). Nucleo de Bioestatistica; Woellner, L.C. [Centro de Medicina Nuclear, Curitiba, PR (Brazil); Goedert, C.A. [Centro de Tomografia Computadorizada, Curitiba, PR (Brazil)

2007-12-15

Recombinant human thyroid-stimulating hormone (rhTSH) enhances {sup 131}I uptake, permitting a decrease in radiation for the treatment of multinodular goiter (MNG). Our objective was to evaluate the safety and efficacy of a single 0.1-mg dose of rhTSH, followed by 30 mCi {sup 131}I, in patients with MNG. Seventeen patients (15 females, 59.0 {+-} 13.1 years), who had never been submitted to {sup 131}I therapy, received a single 0.1-mg injection of rhTSH followed by 30 mCi {sup 131}I on the next day. Mean basal thyroid volume measured by computed tomography was 106.1 {+-} 64.4 mL. {sup 131}I 24-h uptake, TSH, free-T4, T3, thyroglobulin, anti-thyroid antibodies, and thyroid volume were evaluated at regular intervals of 12 months. Mean {sup 131}I 24-h uptake increased from 18.1 {+-} 9.7 to 49.6 {+-} 13.4% (P < 0.001), a median 2.6-fold increase (1.2 to 9.2). Peak hormonal levels were 10.86 {+-} 5.44 mU/L for TSH (a median 15.5-fold increase), 1.80 {+-} 0.48 ng/dL for free-T4, 204.61 {+-} 58.37 ng/dL for T3, and a median of 557.0 ng/mL for thyroglobulin. The adverse effects observed were hyperthyroidism (17.6%), painful thyroiditis (29.4%) and hypothyroidism (52.9%). Thyroid volume was reduced by 34.3 {+-} 14.3% after 6 months (P < 0.001) and by 46.0 {+-} 14.6% after 1 year (P < 0.001). Treatment of MNG with a single 0.1-mg dose of rhTSH, followed by a fixed amount of radioactivity of {sup 131}I, leads to an efficacious decrease in thyroid volume for the majority of the patients, with a moderate incidence of non-serious and readily treatable adverse effects. (author)

Effect of 30 mCi radioiodine on multinodular goiter previously treated with recombinant human thyroid-stimulating hormone

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G.J. Paz-Filho

2007-12-01

Full Text Available Recombinant human thyroid-stimulating hormone (rhTSH enhances 131I uptake, permitting a decrease in radiation for the treatment of multinodular goiter (MNG. Our objective was to evaluate the safety and efficacy of a single 0.1-mg dose of rhTSH, followed by 30 mCi 131I, in patients with MNG. Seventeen patients (15 females, 59.0 ± 13.1 years, who had never been submitted to 131I therapy, received a single 0.1-mg injection of rhTSH followed by 30 mCi 131I on the next day. Mean basal thyroid volume measured by computed tomography was 106.1 ± 64.4 mL. 131I 24-h uptake, TSH, free-T4, T3, thyroglobulin, anti-thyroid antibodies, and thyroid volume were evaluated at regular intervals of 12 months. Mean 131I 24-h uptake increased from 18.1 ± 9.7 to 49.6 ± 13.4% (P < 0.001, a median 2.6-fold increase (1.2 to 9.2. Peak hormonal levels were 10.86 ± 5.44 mU/L for TSH (a median 15.5-fold increase, 1.80 ± 0.48 ng/dL for free-T4, 204.61 ± 58.37 ng/dL for T3, and a median of 557.0 ng/mL for thyroglobulin. The adverse effects observed were hyperthyroidism (17.6%, painful thyroiditis (29.4% and hypothyroidism (52.9%. Thyroid volume was reduced by 34.3 ± 14.3% after 6 months (P < 0.001 and by 46.0 ± 14.6% after 1 year (P < 0.001. Treatment of MNG with a single 0.1-mg dose of rhTSH, followed by a fixed amount of radioactivity of 131I, leads to an efficacious decrease in thyroid volume for the majority of the patients, with a moderate incidence of non-serious and readily treatable adverse effects.

Prevalence and Correlates of Human Herpesvirus 8 Infection among Peruvian Men who have Sex with Men

Science.gov (United States)

Guanira, Juan V.; Casper, Corey; Lama, Javier R.; Morrow, Rhoda; Montano, Silvia M; Caballero, Patricia; Suárez, Luis; Whittington, William L. H.; Wald, Anna; Sanchez, Jorge; Celum, Connie

2011-01-01

Background Infection with human herpesvirus 8 (HHV-8) is common among men who have sex with men (MSM) in North America and Europe, and is also found to be endemic in some regions of South America. Little is known about HHV-8 prevalence and its correlates among MSM in the Andean region. Methods We assessed HHV-8 seroprevalence among 497 MSM recruited for the 2002 Peruvian HIV sentinel surveillance program using a combined HHV-8 enzyme immunoassay and immunofluorescence assay algoritm. Logistic regression was used to estimate Odds Ratios (OR) and their 95% confidence intervals (CI) to determine the association between selected covariates and HHV-8 seropositivity. Results 483 (97%) of 497 men had stored sera and demographic data available for analysis. 131 (66.5%, 95% CI 63.1%-69.9%) of 197 HIV-infected and 80 (26.7%, 95% CI 24.4%-29.0%) of 300 HIV-uninfected MSM had serologic evidence of HHV-8 infection. Factors independently associated with HHV-8 infection were education <12 years (OR 1.7, 95% CI 1.1-2.7), anal receptive sex with the last partner (OR 2.0, 95% CI 1.2-3.3), self-reported STI symptoms during the last year (OR: 1.9, 95% CI 1.2-3.0), and co-infection with HIV (OR 4.2, 95% CI 2.8-6.4) and Chronic Hepatitis B (OR 4.9, 95% CI 1.5-15.8). MSM with long-standing HIV infection were more likely to have serologic evidence of HHV-8 infection when compared to men with recently-acquired HIV (OR: 3.8, 95% CI 1.7-9.1). Conclusions HHV-8 infection is common among both HIV-infected and negative MSM in Lima, Peru. HHV-8 seropositivity is correlated with anal receptive sex, self-reported STI symptoms, and HIV infection among these MSM, and thus appears to be sexually transmitted. HHV-8 infection appears to be acquired after HIV infection, suggesting that future studies should evaluate the mode of HHV-8 transmission and prevention strategies among HIV-infected MSM. PMID:18989224

Incognito ergo sum. O wytwarzaniu obojętności

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Joanna Tokarska-Bakir

2014-06-01

Full Text Available Incognito ergo sum: on indifference  The present article is an analysis of various types of indifference of non-Jewish inhabitants of Warsaw to the plight of Jewish Poles. The words of Krzysztof Dunin-Wąsowicz, a historian and “Żegota” activist, provide the vantage point for the analysis: Dunin-Wąsowicz claimed that around 75 per cent of the inhabitants of Warsaw “were indifferent to what was taking place behind the Ghetto wall”. Thomas Kuhne hypothesised that it was Germans’ indifference to the Jewish – not hatred – that legitimised the Nazi racial policies of the 1930s. This statement might also apply to the “75 per cent of the inhabitants of Warsaw”. The article is mainly based on articles published by ZWZ-AK, in particular Biuletyn Informacyjny.   Incognito ergo sum. O wytwarzaniu obojętności Autorka analizuje różne odcienie obojętności nieżydowskich mieszkańców Warszawy w latach czterdziestych wobec losu żydowskich Polaków. Punktem wyjścia jest zdanie Krzysztofa Dunin-Wąsowicza, historyka i działacza „Żegoty”, który stwierdził, że dla około 75 procent mieszkańców Warszawy „obojętne było to, co działo się poza murem getta”. Powołując się na tezę Thomasa Kuhnego, że to właśnie obojętność Niemców wobec Żydów – a nie nienawiść w stosunku do nich – „spowodowała masowe poparcie nazistowskiej polityki rasowej w latach trzydziestych”, autorka zastanawia się, czy „podobnej opinii nie można by sformułować pod adresem” 75 procent mieszkańców Warszawy. Materiał do analizy stanowią w znacznej mierze publikacje prasy ZWZ-AK, w tym przede wszystkim „Biuletyn Informacyjny”.

CCI and CI Join Hands:A Better Supply Chain with More Innovations on Cotton Fabrics

Institute of Scientific and Technical Information of China (English)

Tom; Xue

2010-01-01

Cotton Council International("CCI")and Cotton Incorporated("CI") joined forces again,from October 19-22,2010 at Intertextile Shanghai,to promote natural fiber-U.S.cotton.As global textile strategic partners,both organizations were bringing together alliances through the cotton

A ciência nas utopias de Campanella, Bacon, Comenius, e Glanvill

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Bernardo Jefferson de Oliveira

2002-12-01

Full Text Available Este artigo analisa comparativamente o papel que a ciência e a técnica ocupam nas sociedades descritas em A cidade do Sol de Tommasio Campanella, a Nova Atlântida de Francis Bacon, Panorthosia de Jan Amós Comenius e o Complemento à Nova Atlântida de Joseph Glanvill.This article evaluates the role that science and technology plays in the societies described by early modern utopias, making a comparative analysis of Tommasio Campanella's City of Sun, Francis Bacon's New Atlantis, Jan Amós Comenius' Panorthosia, and Joseph Glanvill's The summe of my lord Bacon's New Atlantis.

Postawa trenera wobec filozofii karate i jego system wartości, a postawy i systemy wartości jego uczniów = The attitude of the coach to the philosophy of karate and his system of values and attitudes and value systems of its students

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Aleksandra Zienowicz

2015-09-01

(2 Uniwersytet Gdański   „O ile rozwój fizyczny jest początkiem karate, o tyle rozwój duchowy jest celem ostatecznym tej sztuki walki.” Sosai Masutatsu Oyama     Streszczenie Wprowadzenie: Problematyka utrzymania równowagi między życiem osobistym a zawodowym, pęd społeczeństwa, nastawienie na „mieć” (por. Gałkowska-Jakubik, 2007 skłania do refleksji na temat roli systemów wartości w życiu człowieka (Matusewicz, 1975. Punktem wyjścia były założenia filozofii karate oraz komercjalizacja tej sztuki walki, która wyłania dwa style: sportowy, skupiony na wyniku, sukcesie oraz styl tradycyjny, który koncentruje się na utrzymywaniu równowagi psychofizycznej, rozwoju duchowym prowadzącym do doskonałości moralnej (Miłkowski, 1983, Budnik, 2005. Cel pracy: Celem przedstawionego badania jest eksploracja systemów wartości trenerów oraz ich uczniów, z uwzględnieniem opinii uczniów na temat swoich wychowawców, w oparciu o praktykowany styl. Materiał i metoda: Uczestnikami badania było 22 trenerów oraz 54 uczniów karate. Analiza wyników skali, stworzonej na potrzeby badania, postawa wobec filozofii (PwF, wyłoniła 11 trenerów, 35 uczniów „sportowych” oraz 11 trenerów, 19 uczniów „tradycjonalistów”. Badanie przeprowadzono wykorzystując skalę wartości schelerowskich (Brzozowski, 1995 Wyniki: Zgodnie z założeniami trenerzy i uczniowie “tradycjonaliści” uzyskali wyższe wyniki na skali wartości moralnych oraz podskali czynnikowej świętości religijnych Wnioski:  „Tradycjonaliści” kierują się ascetycznym wzorem edukacyjnym, który zakłada, że poprzez rozwój fizyczny oraz duchowy dąży się do doskonałości moralnej. Wartości wynikające z duchowości stanowią nierozłączny element dobrego życia.   Słowa kluczowe: karate, wartości, trener-uczeń.   Abstract Introduction: The issue of maintaining the balance between personal and professional lives, society  ofrush, the attitude to "be

WPŁYW SUBSTYTUCJI WŁÓKIEN BAZALTOWYCH PRZEZ WŁÓKNA WĘGLOWE NA WŁAŚCIWOŚCI MECHANICZNE PRĘTÓW B/CFRP (HFRP

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Kostiantyn PROTCHENKO

2016-07-01

Full Text Available W niniejszym artykule przedstawiono analityczne i numeryczne obliczenia mechanicznych właściwości obecnie opracowywanych prętów hybrydowych HFRP (Hybrid Fibre Reinforced Polymer powstałych poprzez zastąpienie (substytucję części włókien bazaltowych BFRP (Basalt Fibre Reinforced Polymer włóknami węglowymi CFRP (Carbon Fibre Reinforced Polymer. W tym aspekcie termin ,,substytucja” rozumiany będzie jako modyfikacja prętów BFRP polegająca na zastąpieniu pewnej części włókien bazaltowych przez włókna węglowe. Celem analizy jest określenie optymalnego modelu prętów hybrydowych HFRP, które stanowiłyby realną alternatywę dla prętów stalowych stosowanych do zbrojenia konstrukcji betonowych. Zamiana włókien bazaltowych, włóknami węglowymi prowadzi do uzyskania lepszych właściwości mechanicznych prętów. Względy ekonomiczne skłaniają do ograniczenia procentowego udziału włókien węglowych w prętach HFRP do rozsądnej wielkości, oraz zastosowaniu włókien węglowych o stosunkowo niedużej wytrzymałości (Low Strength Carbon Fibres jak na włókna CFRP. W pracy przedstawiony został opis struktury pręta hybrydowego, oszacowanie właściwości mechanicznych wzdłuż i w poprzek włókien, a także wpływ układu włókien w przekroju poprzecznym pręta na jego zachowanie mechaniczne. Analizę przeprowadzono dla różnych proporcji udziału włókien węglowych do włókien bazaltowych (1:9; 1:4; 1:3; 1:2; 1:1 w prętach HFRP. Rozpatrzono dwa przypadki rozmieszczenia włókien w przekroju poprzecznym pręta (Bar Architecture. Pierwszy z włóknami węglowymi zlokalizowanymi w rdzeniu, natomiast drugi z włóknami węglowymi usytuowanymi w powierzchniowej warstwie pręta.

Dylematy etyczno‑prawne związane z hospitalizacją psychiatryczną kobiety w ciąży

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Błażej Kmieciak

2011-12-01

Full Text Available Przeprowadzone w ciągu ostatnich kilku lat badania społeczne dowodzą, że coraz więcej Polaków korzysta z pomocy psy‑ chiatrycznej opieki zdrowotnej. Do szpitali psychiatrycznych zgłasza się także coraz więcej pacjentek w ciąży. Nie tylko leczenie, ale cały proces hospitalizacji pacjentki w ciąży stanowi niezwykłe wyzwanie dla personelu lekarsko‑pielęgniar‑ skiego. Psychiatryczna hospitalizacja pacjentki spodziewającej się potomstwa w sposób szczególny musi uwzględniać fundamentalną w polskiej psychiatrii zasadę najmniejszej uciążliwości. Poniższy artykuł ma na celu ukazanie kilku dyle‑ matów, jakie wiążą się z leczeniem i opieką nad tą grupą pacjentek. Przedstawione zostaną przykłady związane z przy‑ musową hospitalizacją, stosowaniem przymusu bezpośredniego oraz stosowaniem zabiegów elektrowstrzasów wobec pacjentek spodziewających się dziecka, a także zasady, jakich należy przestrzegać w trakcie wykonywania wspomnia‑ nych działań. Omówione zostanie również szczególnie delikatne zagadnienie dotyczące tzw. psychiatrycznych przesła‑ nek uprawniających do wykonania aborcji. Zagadnienie to, komentowane głównie poza granicami naszego kraju, powin‑ no być przeanalizowane także z perspektywy polskich przepisów prawa. Dlatego też w odniesieniu do proponowanego tematu, bazując na konkretnym kazusie, z jednej strony zostaną przedstawione informacje dotyczące polskich oraz za‑ granicznych podstaw prawnych uprawniających do dokonania aborcji, z drugiej – wyniki badań ukazujących wyraźnie niebezpieczeństwo legalizacji wspomnianych praktyk, co istotne – niebezpieczeństwo odnoszące się bezpośrednio do po‑ gorszenia się stanu zdrowia psychicznego pacjentki poddającej się zabiegowi przerwania ciąży.

Prevalence of goiter and thyroid nodules before and after implementation of the universal salt iodization program in mainland China from 1985 to 2014: a systematic review and meta-analysis.

Directory of Open Access Journals (Sweden)

Wei Zhao

Full Text Available OBJECTIVES: We comprehensively estimated the prevalence of goiter and thyroid nodules (TNs before and after the implementation of the Universal Salt Iodization (USI program in mainland China and provided information for creating effective health policies. METHODS: PubMed, Google Scholar, CNKI, Chinese Wanfang and Chongqing VIP databases were searched for relevant studies from Jan 1985 to Feb 2014. Data from eligible citations were extracted by two independent reviewers. All analyses were performed with Stata 11.0 and SPSS 17.0. RESULTS: Eligible articles (N = 31; 4 in English and 27 in Chinese included 52 studies (15 about goiter rates made before 1996 and 14 afterwards, and 23 about TNs. Our meta-analysis suggests a pooled prevalence for goiter before and after 1996 and for TNs of 22.8% (95% CI: 15.3%, 30.3%, 12.6% (95% CI: 9.4%, 15.8% and 22.7% (95% CI: 18.3%, 27.0%, respectively. Egger's test of three independent categories revealed no evidence of publication bias (p = 0.101, 0.148 and 0.113, respectively. CONCLUSIONS: The prevalence of goiter was reduced by almost half after 1996 in mainland China, so the USI program was considered beneficial. However, subgroup analysis suggests that both insufficient and excess iodine may be associated with goiter. The prevalence of goiter and TNs increased significantly after 2002, suggesting a risk of excessive iodine intake. Thus, salt iodization standardizations should be set according to local conditions.

Posições subjetivistas e objetivistas de ciência: a hermenêutica como fundamento da pesquisa qualitativa

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João Manoel Roratto

2010-04-01

Full Text Available Este trabalho discute aspectos relacionados à evolução recente da ciência, com ênfase no conflito entre posições objetivistas e subjetivistas, até chegar à importância da pesquisa qualitativa na construção do conhecimento científico na atualidade, com base nos variados campos de tradição e linhas de pensamento nas ciências sociais e nas formulações teóricas de Gadamer sobre hermenêutica. Nos estudos de Denzin e Lincoln, analisa-se a relevância da pesquisa qualitativa nos últimos tempos e sua forma metodológica diversificada e peculiar de representar as diferentes realidades que compõem o universo social, bem como as expectativas desse modelo de pesquisa a se afirmar como ciência. Em Gadamer, busca-se entender a construção do processo retórico e hermenêutico como método para compreender e explicar a realidade social, cujas bases ontológicas estão nas ideias originais de Platão sobre discurso e de Aristóteles sobre filosofia prática.

A Administração é uma Ciência? Reflexões Epistemológicas acerca de sua Cientificidade

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Elói Júnior Damke

2010-12-01

Full Text Available Este estudo de caráter epistemológico tem como objetivo expor e discutir a questão da cientificidade da administração. Essa discussão já foi realizada em outros estudos, sem ter sido, contudo, a exemplo deste estudo, efetuado por meio da análise dos critérios epistemológicos dos filósofos Karl Popper, Thomas Kuhn e Imre Lakatos. Com base nas correntes epistemológicas apresentadas, pode-se concluir: que a administração, como teoria do conhecimento, pode ser considerada ciência, o que decorre da possibilidade de falsear os estudos dessa área conforme o falseacionismo sofisticado de Popper; que a administração atende aos pressupostos da ciência paradigmática de Kuhn, apesar de não existir consenso sobre em que etapa se encontra e se adéqua aos moldes dos programas de pesquisa apresentados por Lakatos. Sabe-se que a administração ainda possui um longo caminho a percorrer em busca da ampliação de seu rigor metodológico e de seu amadurecimento, mas desconsiderá-la como ciência, além de não auxiliar neste amadurecimento, acaba por desprestigiar um amplo grupo de atores sociais – as organizações – que não são objeto principal de estudo de outras ciências.

In-cylinder visualization and engine out emissions from CI to PPC for fuels with different properties

KAUST Repository

An, Yanzhao; Vallinayagam, R.; Vedharaj, S.; Masurier, Jean-Baptiste; Najafabadi, Mohammad Izadi; Somers, Bart; Johansson, Bengt

2018-01-01

This study investigated the transition from conventional Compression Ignition (CI) to Partially Premixed Combustion (PPC) in an optical engine for fuels with differing properties. Combustion stratification and emissions were measured with diesel

Preparation of C.I. Pigment 52:1 anion-pillared layered double hydroxide and the thermo- and photostability of the resulting intercalated material

Science.gov (United States)

Guo, Shengchang; Evans, David G.; Li, Dianqing

2006-05-01

Intercalation of 2-naphthalenecarboxylic acid, 4-((4-chloro-5-methyl-2-sulfophenyl) azo)-3-hydroxy-, calcium salt (1:1) (C.I. Pigment Red 52:1, also known as New Rubine S6B) into a layered double hydroxide (LDHs) host was carried out using MgAl NO3 LDHs as a precursor in an effort to improve the thermal and photo stability of the pigment. After intercalation, the powder X-ray diffraction (XRD) pattern shows that the basal spacing of the LDHs increased from 0.86 to 1.92 nm. Infrared spectra and TG DTA curves demonstrate that there are supramolecular host guest interactions. It was found that the intercalated material is more stable than the pristine pigment at high temperatures. The pigment anion-pillared LDHs also exhibit much higher photostablity to UV-light than the pristine pigment.

As ciências da psique no espiritismo brasileiro: C. 1900-C. 1960

OpenAIRE

Leite, Igor Alleoni Silveira

2016-01-01

As Ciências da Psique no período que abrange 1900 a 1960 envolvem concepções que remetem nomeadamente à Psiquiatria e a insipiente Psicologia, mas também outras correntes que geraram embates ou simpatizantes frente ao Espiritismo brasileiro, entre elas estaria a Parapsicologia. A região estudada envolve o estado de São Paulo, levando-se em consideração o tempo histórico em que fatores importantes ocorreram no período estabelecido, como os dados identificados na literatura que apontam os confl...

A abordagem de questões sociocientíficas na formação continuada de professores de ciências: contribuições e dificuldades

OpenAIRE

Martínez Pérez, Leonardo Fabio [UNESP

2010-01-01

A perspectiva Ciência, Tecnologia, Sociedade e Ambiente (CTSA), nas últimas décadas, tem se constituído uma alternativa de renovação curricular para o ensino de ciências em vários países do mundo. Assim, currículos de ciências, projetos escolares e pesquisas didáticas tem adotado, en seus fundamentos, orientações desta perspectiva. No entanto, apresentam-se problemas no desenvolvimento da perspectiva CTSA nas práticas docentes dos professores de ciências em serviço. Neste contexto, esta pesqu...

Engineering of a genetically encodable fluorescent voltage sensor exploiting fast Ci-VSP voltage-sensing movements

DEFF Research Database (Denmark)

Lundby, Alicia; Mutoh, Hiroki; Dimitrov, Dimitar

2008-01-01

Ci-VSP contains a voltage-sensing domain (VSD) homologous to that of voltage-gated potassium channels. Using charge displacement ('gating' current) measurements we show that voltage-sensing movements of this VSD can occur within 1 ms in mammalian membranes. Our analysis lead to development...

Neck and whole-body scanning with 5-mCi dose of (123)I as diagnostic tracer in patients with well-differentiated thyroid cancer.

Science.gov (United States)

Gulzar, Z; Jana, S; Young, I; Bukberg, P; Yen, V; Naddaf, S; Abdel-Dayem, H M

2001-01-01

To determine whether a 5-mCi dose of 123I can be used as an effective radiotracer for assessing the presence of remnant thyroid tissue and for searching for metastatic lesions in patients with well-differentiated thyroid cancer as well as to attempt to ascertain whether a scan performed only at 4 hours is sufficient for accurate diagnosis and might replace the conventional protocol of scanning at both 4 hours and 24 hours. We prospectively studied 27 patients who had undergone near-total thyroidectomy and had a documented diagnosis of well-differentiated thyroid carcinoma. Patients underwent scanning after receiving a 5-mCi dose of 123I, at a time when they had discontinued thyroid replacement therapy and had a thyrotropin level in excess of 30 mIU/mL. Whole-body images at 4 hours and 24 hours were obtained and were compared with posttherapy scans obtained 5 to 7 days after administration of 131I. Scans were interpreted by two board-certified nuclear medicine physicians. Of the 27 patients, 2 (7.4%) showed discordance between the 123I scan performed at 24 hours and the posttherapy 131I scan. When 4-hour images after administration of 123I were compared with the posttherapy 131I scans, a discordance rate of 14.8% (4 of 27 patients) was noted. In addition, two of these four patients showed lesions on the 24-hour images that were not seen on the 4-hour images (one with new lung metastatic involvement and the other with a local recurrence in the lower neck area). The prognosis and treatment of these two patients were substantially changed by the result of the 24-hour images. On comparison of scans obtained after administration of a 5-mCi dose of 123I with those obtained after 131I therapy, we conclude that 5 mCi of 123I produces images that have excellent quality and resolution and also compare favorably with those obtained after 131I therapy. Furthermore, a decrease in the dose of 123I from 10 mCi to 5 mCi lowered the cost of the study without compromising the

Natural-gas fueled spark-ignition (SI) and compression-ignition (CI) engine performance and emissions

Energy Technology Data Exchange (ETDEWEB)

Korakianitis, T.; Namasivayam, A.M.; Crookes, R.J. [School of Engineering and Materials Science, Queen Mary University of London (United Kingdom)

2011-02-15

Natural gas is a fossil fuel that has been used and investigated extensively for use in spark-ignition (SI) and compression-ignition (CI) engines. Compared with conventional gasoline engines, SI engines using natural gas can run at higher compression ratios, thus producing higher thermal efficiencies but also increased nitrogen oxide (NO{sub x}) emissions, while producing lower emissions of carbon dioxide (CO{sub 2}), unburned hydrocarbons (HC) and carbon monoxide (CO). These engines also produce relatively less power than gasoline-fueled engines because of the convergence of one or more of three factors: a reduction in volumetric efficiency due to natural-gas injection in the intake manifold; the lower stoichiometric fuel/air ratio of natural gas compared to gasoline; and the lower equivalence ratio at which these engines may be run in order to reduce NO{sub x} emissions. High NO{sub x} emissions, especially at high loads, reduce with exhaust gas recirculation (EGR). However, EGR rates above a maximum value result in misfire and erratic engine operation. Hydrogen gas addition increases this EGR threshold significantly. In addition, hydrogen increases the flame speed of the natural gas-hydrogen mixture. Power levels can be increased with supercharging or turbocharging and intercooling. Natural gas is used to power CI engines via the dual-fuel mode, where a high-cetane fuel is injected along with the natural gas in order to provide a source of ignition for the charge. Thermal efficiency levels compared with normal diesel-fueled CI-engine operation are generally maintained with dual-fuel operation, and smoke levels are reduced significantly. At the same time, lower NO{sub x} and CO{sub 2} emissions, as well as higher HC and CO emissions compared with normal CI-engine operation at low and intermediate loads are recorded. These trends are caused by the low charge temperature and increased ignition delay, resulting in low combustion temperatures. Another factor is

Study for optimization of a {sup 60} Co industrial irradiator of 250 k Ci.; Estudio para la optimizacion de un irradiador industrial de {sup 60} Co de 250 kCi.

Energy Technology Data Exchange (ETDEWEB)

Pina V, G

1996-12-31

This work presents results of a benchmark between calculated and experimental absorbed dose values for a typical product, in a {sup 60} Co industrial irradiator, located at ININ, Mexico. The goal of this work is to reach a {+-} 10 % approximation between both values. ININ {sup 60} Co industrial irradiator is a two level, two layer system with overlapping product configuration, 56 irradiation positions with an activity of around 250 k Ci. Calculated values were obtained by QAD-CGGP code. This code uses a point kernel technique, build-up factors fitting was done by geometrical progression and combinatorial geometry was used for 3 D system description. Main code modifications were related with source simulation by punctual sources and energy spectrum (16 energy groups) and anisotropic emission were also considered. Experimental data were obtained from routine dosimetry which was done with red acrylic pellets; they were irradiated together the product in predetermined positions, for 36 maximum and minimum absorbed dose values. Typical product was polypropylene Petri dish packages, apparent density 0.13 g/cm{sup 3}. It was chosen because regular geometry (2 packages per full irradiator container) and enough amount for considering homogeneous loading inside irradiation chamber. Required minimum dose was 15 kGy. Results showed a 8% variation between calculated and experimental values for maximum absorbed dose (18.2 kGy vs 16.8 kGy) and 3 % variation for minimum absorbed dose (13.8 kGy vs 14.3 kGy); these results fixed with the original proposal. (Author).

Life cycle impact assessment of biodiesel using the ReCiPe method

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Kiss Ferenc E.

2013-01-01

Full Text Available This paper presents the life cycle impact assessment (LCIA results of biodiesel produced from rapeseed oil. The functional unit (FU is defined as 3750 km of distance traveled by a truck fuelled with biodiesel. The reference flow is 1000 kg of biodiesel. The LCIA method used in the study is the ReCiPe method. At midpoint level the ReCiPe method addresses environmental issues within 18 impact categories. Most of these midpoint impact categories are further converted and aggregated into 3 endpoint categories (damage to human health, damage to ecosystem diversity, damage to mineral resource availability. The total impact of biodiesel’s life cycle was estimated at 540 Pt/FU. The damage to ecosystem diversity (1.48E-04 species•year/FU, the damage to human health (7.48E-03 DALY/FU and the damage to mineral resource availability (8.11E+03 US$/FU are responsible for 63%, 27% and 10% of the total negative impact in the life cycle of biodiesel, respectively. The results have revealed that only 4 impact categories are responsible for most of the impacts within the specific endpoint categories. These are impacts associated with global warming (3000 kg CO2 ekv./FU, particulate matter formation (12.4 kg PM ekv./FU, agricultural land occupation (6710 m2a./FU and fossil fuel depletion (21168 MJ/FU. Greenhouse gases emitted in the life cycle of biodiesel (mainly N2O, CO2 are responsibly for 56% of the damage caused to human health and for 16% of the damage caused to ecosystem diversity. Airborne emissions which contribute to particulate matter formation (NOx, NH3, PM, SO2 are responsible for 43% of the damage caused to human health. Agricultural land occupation is responsible for 82% of the damage caused to the ecosystem diversity. Damage to mineral resource availability is almost entirely related to the depletion of fossil energy sources. The production chain of biodiesel and the combustion of biodiesel are responsible for 69% and 31% of the total impact of

Informação como objeto para construção do corpus interdisciplinar entre Ciência da Informação e Ciência da Administração | Information from object to construction to interdisciplinary corpus between Information Science and Administrative Science

Directory of Open Access Journals (Sweden)

Joaquim Francisco Cavalcante de Oliveira

2011-03-01

Full Text Available Resumo Descrição e análise dos fundamentos teóricos e procedimentos metodológicos para a construção de um corpus interdisciplinar, compreendido como “o conjunto de categorias interdisciplinares afins e de significados próximos, valorizados por duas ou mais Ciências”, nesta pesquisa entre a Ciência da Informação e a Ciência da Administração, com base na informação e gestão da informação. As etapas de seu desenvolvimento incluem o referencial teórico em torno da interdisciplinaridade das áreas estudadas, especialmente Heckhausen; pesquisa documental para identificação dos autores de Ciência da Informação e de Ciência da Administração, identificados via Currículo Lattes e Diretório de Grupos de Pesquisa do CNPq e autores estrangeiros por meio do Google. A partir da análise de citação e a análise de conteúdo em revistas brasileiras de Administração e Ciência da Informação selecionadas e da identificação dos conceitos contidos em artigos, foi construído o corpus interdisciplinar. Esta metodologia tem aplicação mais ampla e pode ser adotada em pesquisas semelhantes de interdisciplinaridade de outros campos do conhecimento. Palavras-chave interdisciplinaridade; Ciência da Informação; Ciência da Administração; informação; metodologia da pesquisa; corpus interdisciplinar; gestão da informação. Abstract A description and analysis of the theoretical foundations and methodological procedures in the development of an interdisciplinary corpus, defined/described as “a group of related interdisciplinary categories and similar meanings, recognized by two or more Sciences”, the article presents results of research between Information Science and Administrative Science, based on information and information management. The stages of its development include the theoretical referential that surrounds the interdisciplinarity of the studied areas, especially Heckhausen: documental research for the

40 CFR 60.4203 - How long must my engines meet the emission standards if I am a stationary CI internal combustion...

Science.gov (United States)

2010-07-01

... emission standards if I am a stationary CI internal combustion engine manufacturer? 60.4203 Section 60.4203... Combustion Engines Emission Standards for Manufacturers § 60.4203 How long must my engines meet the emission standards if I am a stationary CI internal combustion engine manufacturer? Engines manufactured by...

Reduced dietary salt for the prevention of cardiovascular disease

Science.gov (United States)

Taylor, Rod S; Ashton, Kate E; Moxham, Tiffany; Hooper, Lee; Ebrahim, Shah

2014-01-01

Background An earlier Cochrane review of dietary advice identified insufficient evidence to assess effects of reduced salt intake on mortality or cardiovascular events. Objectives To assess the long term effects of interventions aimed at reducing dietary salt on mortality and cardiovascular morbidity. To investigate whether blood pressure reduction is an explanatory factor in any effect of such dietary interventions on mortality and cardiovascular outcomes. Search methods The Cochrane Library (CENTRAL, Health Technology Assessment (HTA) and Database of Abstracts of Reviews of Effect (DARE)), MEDLINE, EMBASE, CINAHL and PsycInfo were searched through to October 2008. References of included studies and reviews were also checked. No language restrictions were applied. Selection criteria Trials fulfilled the following criteria: (1) randomised with follow up of at least six-months, (2) intervention was reduced dietary salt (restricted salt dietary intervention or advice to reduce salt intake), (3) adults, (4) mortality or cardiovascular morbidity data was available. Two reviewers independently assessed whether studies met these criteria. Data collection and analysis Data extraction and study validity were compiled by a single reviewer, and checked by a second. Authors were contacted where possible to obtain missing information. Events were extracted and relative risks (RRs) and 95% CIs calculated. Main results Six studies (including 6,489 participants) met the inclusion criteria - three in normotensives (n=3518), two in hypertensives (n=758), and one in a mixed population of normo- and hypertensives (n=1981) with end of trial follow-up of seven to 36 months and longest observational follow up (after trial end) to 12.7 yrs. Relative risks for all cause mortality in normotensives (end of trial RR 0.67, 95% CI: 0.40 to 1.12, 60 deaths; longest follow up RR 0.90, 95% CI: 0.58 to 1.40, 79 deaths) and hypertensives (end of trial RR 0.97, 95% CI: 0.83 to 1.13, 513 deaths

Relações interdisciplinares entre a Ciência da Informação e a Ciência da Comunicação: uma análise a partir de citações, formação das bancas e palavras-chave das teses das áreas

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João de Melo Maricato

Full Text Available RESUMO Estuda relações interdisciplinares nas e entre as áreas de Ciência da Informação e da Ciência da Comunicação, discutindo as mudanças de paradigmas que têm acontecido nessas disciplinas. Analisa as relações interdisciplinares com métodos bibliométricos e cientométricos, especificamente análises de coocorrência e cocitação. Coletou-se dados de teses de 4 programas de pós-graduação brasileiros (10 teses de cada um dos programas e analisou-se relações entre as citações, entre a titulação da banca e entre as palavras-chave, com intuito de identificar coocorrências e, consequentemente, relações interdisciplinares nas e entre as duas áreas. Constatou-se que existem fortes relações quanto à análise de cocitação; grande variedade de formações dos membros das bancas e relativamente alta coocorrência destas entre as áreas, porém, mais intensas na área de Ciência da Informação e com mais interesse desta na área Ciência da Comunicação; não foram identificadas relações entre as duas áreas por meio da análise de coocorrência de palavras-chave. Conclui-se que ambas as áreas possuem características fortemente interdisciplinares, no entanto, são mais intensas da área de Ciência da Informação do que da Ciência da Comunicação, havendo mais interesse da primeira área na segunda.

Desenvolvimento de recursos didáticos para o ensino de geociências para a Banca das Ciências e Experimentoteca da EACH/USP

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Caroline Bertocco Garcia

2015-06-01

Full Text Available O presente trabalho abrange a importância da divulgação e popularização da Ciência com o uso de modelos didáticos que expressem os conteúdos de Geociências. A divulgação e popularização da Ciência tem como cenário a Banca da Ciência, um projeto ligado ao Laboratório de Desenvolvimento de Recursos Didáticos em Ciência da Natu­reza, LABDID da Escola de Artes, Ciências e Humanidades, EACH-USP. Foram utilizados materiais simples, como papel cartonado de caixa descartáveis, canudos para refrigerante, cola quente, copos de iogurte descartáveis etc. e atividades apresentadas em publicações científicas da área de ensino de Geociências e do site Geoideias, para compor o acervo da Banca da Ciência, assim como para ampliar o tema Geologia no acervo da Experimentoteca do LABDID. A acessibilidade dos materiais para a construção dos modelos foi vista como um meio para a popularização das Geociências, na qual a escolha de materiais reciclados e de baixo custo permitisse a reprodução e adaptação dos modelos.

Układ pojęć konstytuujących teorię rachunkowości w kontekście nauk ekonomicznych

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Mieczysław Dobija

2016-09-01

Full Text Available Każda teoria wyjaśniająca zjawiska rzeczywistego świata ma za podstawę pojęcia pierwotne i fundamen-talne zasady oraz definicje podstawowych koncepcji, które następnie są materią do formułowania stwier-dzeń orzekających, przy zastosowaniu logiki i postępowania naukowego. Powstaje zatem pytanie, czy ten podstawowy zbiór pojęć dla wiedzy zwanej rachunkowością pokrywa się z odpowiednikiem z zakresu ekonomii. Analiza tej kwestii jest bezsprzecznie zasadna, ponieważ już kategoria kapitału ma w rachun-kowości nierzadko inne znaczenie niż w ekonomii czy w naukach o zarządzaniu. Rozważania prowadzą do wniosku, że podstawowy układ pojęć konstytuujący teorię rachunkowości jest jednoznacznie określo-ny, natomiast ten stan niekoniecznie występuje w innych naukach ekonomicznych. Różnią się też kon-cepcje i podejścia do kategorii wartości, co powoduje, że dyscypliny nauk ekonomicznych są w małym stopniu komplementarne.

Concepções de ciência de um grupo de licenciandas em Pedagogia e suas relações com o processo formativo

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Ana Lúcia Santos Souza

2015-12-01

Full Text Available ResumoEste artigo apresenta uma análise das concepções de ciência de um grupo de licenciandas de um curso de Licenciatura em Pedagogia e suas relações com as concepções apresentadas em documentos do curso e pela docente da disciplina Conteúdos e Metodologia do Ensino Fundamental de Ciências. Partimos das seguintes questões: uais as concepções de ciência demonstradas por concluintes do curso de Licenciatura em Pedagogia? Como essas concepções podem estar relacionadas ao processo formativo das licenciandas? O estudo ampara-se teoricamente em Habermas, que considera três tradições das ciências: empírico-analítica, histórico-hermenêutica e crítica. Os dados foram constituídos por meio de documentos e entrevistas semiestruturadas. Os resultados demonstraram que a abordagem crítica que fundamenta o curso não foi materializada na construção ou revisão das concepções de ciência das discentes durante seu processo formativo, prevalecendo entre as mesmas, sobretudo, concepções de cunho positivista.

Contribuição das ciências cognitivas e da ciência da informação para representação da informação: proposta para utilização na construção de biblioteca virtual temática em saúde

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Leandro Guedes da Fonseca

2012-01-01

Full Text Available Aborda aspectos das Ciências Cognitivas que podem aprimorar a representação da informação na construção de bibliotecas virtuais temáticas em saúde, visando sua utilização por distintos tipos de usuários. Mostra as vantagens das novas tecnologias de informação e comunicação, que possibilita maior dinamismo nos fluxos de informação e propicia o seu compartilhamento simultâneo. Apresenta o surgimento das Ciências Cognitivas e suas relações com a Ciência da Informação. Discorre sobre características e funcionalidades desejáveis para uma biblioteca virtual temática. Descreve a importância da contribuição da Ciência da Informação para a sociedade. Conclui ratificando a importância do caráter interdisciplinar das áreas, com vistas ao aprimoramento de produtos e serviços de informação em benefício do usuário.

Czynniki ryzyka upadków i złamań kości u pacjentów chorych na reumatoidalne zapalenie stawów

Directory of Open Access Journals (Sweden)

Krzysztof Tomaszewski

2010-04-01

Full Text Available Cel pracy: Ocena czynników ryzyka i częstości występowaniaupadków i złamań kości u chorych na reumatoidalne zapaleniestawów (RZS. Materiał i metody: Do badania kwalifikowano pacjentów chorychna RZS (spełniających kryteria ACR z 1984 r.. Dane na temat stanuzdrowia zebrano na podstawie ankiety zawierającej Kwestio -nariusz Oceny Stanu Zdrowia (HAQ, pytań dotyczących chorób,przyjmowanych leków, upadków i złamań kości w okresie ostatnich12 miesięcy. Wyniki: Przebadano 167 kobiet (89,8% i 19 mężczyzn (średni wiek± SD 58,5 ±13,8 roku. Średni czas trwania choroby wynosił14,4 ±10,7 roku. Średnia wartość HAQ 1,36 ±0,76. Z grupy 186 osóbupadek przydarzył się 80 badanym (43%. U 28 chorych (35%upadek zakończył się złamaniem bądź złamaniami obwodowymi.Liczba upadków dodatnio korelowała z wynikiem HAQ (r = 0,32;p < 0,05 oraz czasem trwania choroby (r = 0,31; p < 0,05.Głównymi czynnikami ryzyka upadków w badanej grupie byłyzawroty głowy [iloraz szans (OR = 2,68], stosowanie lekówhipotensyjnych (OR = 2,27 i przeciwdepresyjnych (OR = 2,56,deformacje stóp (OR = 3,14 oraz wysoki wskaźnik HAQ(OR = 2,08. Czas trwania RZS (OR = 1,05 i wiek (OR = 1,04 praktycznienie wpływały na ryzyko upadków. Głównymi czynnikamiryzyka złamań kości w badanej grupie były osteoporoza (t-score< –2,5 (OR = 4,70, stosowanie leków hipotensyjnych (OR = 4,98,deformacje stóp (OR = 4,82, zawroty głowy (OR = 3,30 orazwysoki wskaźnik HAQ (OR = 3,12. Wnioski: Upadki są poważnym problemem w przebiegu RZS.Głównymi czynnikami sprzyjającymi upadkom i złamaniomu chorych na RZS są deformacje stóp, zawroty głowy, zażywanieleków obniżających ciśnienie tętnicze oraz wysoka wartość HAQ.

The Stool DNA Test is More Accurate than the Plasma Septin 9 Test in Detecting Colorectal Neoplasia

Science.gov (United States)

Ahlquist, David A.; Taylor, William R.; Mahoney, Douglas W.; Zou, Hongzhi; Domanico, Michael; Thibodeau, Stephen N.; Boardman, Lisa A.; Berger, Barry M.; Lidgard, Graham P.

2014-01-01

Background & Aims Several noninvasive tests have been developed for colorectal cancer (CRC) screening. We compared the sensitivities of a multi-marker test for stool DNA (sDNA) and a plasma test for methylated Septin 9 (SEPT9) in identifying patients with large adenomas or CRC. Methods We analyzed paired stool and plasma samples from 30 patients with CRC and 22 with large adenomas from Mayo Clinic archives. Stool (n=46) and plasma (n=49) samples from age- and sex-matched patients with normal colonoscopy results were used as controls. The sDNA test is an assay for methylated BMP3, NDRG4, vimentin, and TFPI2; mutant KRAS; the β-actin gene, and quantity of hemoglobin (by the porphyrin method). It was performed blindly at Exact Sciences (Madison WI); the test for SEPT9 was performed at ARUP Laboratories (Salt Lake City UT). Results were considered positive based on the manufacturer's specificity cutoff values of 90% and 89%, respectively. Results The sDNA test detected adenomas (median 2 cm, range 1–5 cm) with 82% sensitivity (95% confidence interval [CI], 60%–95%); SEPT9 had 14% sensitivity (95% CI, 3%–35%; P=.0001). The sDNA test identified patients with CRC with 87% sensitivity (95% CI, 69%–96%); SEPT9 had 60% sensitivity (95% CI, 41%–77%; P=.046). The sDNA test identified patients with stage I–III CRC with 91% sensitivity (95% CI, 71%–99%); SEPT9 had 50% sensitivity (95% CI, 28%–72%; P=.013); for stage IV CRC, sensitivity values were 75% (95% CI, 35%–97%) and 88% (95% CI, 47%–100%), respectively (P=.56). False-positive rates were 7% for the sDNA test and 27% for SEPT9. Conclusions Based on analyses of paired samples, the sDNA test detects non-metastatic CRC and large adenomas with significantly greater levels of sensitivity than the SEPT9 test. These findings might be used to modify approaches for CRC prevention and early detection. PMID:22019796

Parametric Factors for the Tangential-Rotary Picks Quality Assessment / Wskaźniki Parametryczne Oceny Jakości Noży Styczno-Obrotowych

Science.gov (United States)

Krauze, Krzysztof; Bołoz, Łukasz; Wydro, Tomasz

2015-03-01

Procedure of the quality assessment of tangential-rotary picks used in various types of mining machines, has been described in the present study. Authorial method of the quality assessment of tangential- -rotary picks based on examination of geometrical and material factors, including pick wear rate, has been discussed. The method is based on parametrical factors and the described examinations tailored to determined conditions of the machine operations, including user requirements. Testing results collected in form of measurement cards allow selection of the optimal pick, including the influence of chosen parameters into the pick wear rate. Frezujące organy są elementami roboczymi wielu maszyn takich jak górnicze kombajny ścianowe i chodnikowe, frezarki pracujące w przemyśle skalnym oraz frezarki drogowe i spągowe. Urabianie organami wyposażonymi w noże styczno-obrotowe znajduje obecnie wiele zastosowań do skrawania węgla, rud metali, skał, betonu oraz asfaltu. Noże te wyparły starsze rozwiązania, czyli noże styczne oraz promieniowe, dzięki większej trwałości oraz zachowaniu podczas eksploatacji odpowiedniego kształtu ostrza czyli prawidłowych kątów skrawania. Maszynom urabiającym, a w szczególności kombajnom ścianowym oraz chodnikowym stawia się coraz bardziej restrykcyjne wymagania dotyczące wydajności, niezawodności, bezpieczeństwa i komfortu pracy załogi. W celu zapewnienia prawidłowej pracy maszyny należy w pierwszym rzędzie zadbać o prawidłowy dobór narzędzi skrawających wraz z uchwytami nożowymi oraz organem urabiającym. Mając na uwadze procedury przetargowe oraz prawo zamówień publicznych obowiązujące w Polsce opracowano taki sposób badania noży, aby możliwe było jednoznaczne wybranie najlepszej oferty przy zachowaniu jak najniższej ceny. Wskaźniki oceny jakości noży zostały sparametryzowane, dzięki czemu możliwe jest dostosowanie opracowanych procedur do badania noży styczno

Conceito de Responsabilidade Social da Ciência da InformaçãoConcepto de Responsabilidad Social de la Ciencia de la Información

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Esdras Renan Farias Dantas

2012-01-01

Full Text Available Introdução: A Responsabilidade Social prevê e estimula maior interação entre organizações empresariais e sociedade, governos e sociedade, instituições e mercados, e assim sucessivamente. Antes restrita à administração, à gestão e ao marketing, em especial, ao marketing social, nos dias de hoje, tende a se expandir para os demais campos, incluindo a Ciência da Informação.Objetivo: Apresentar conceituação em torno da expressão Responsabilidade Social da Ciência da Informação, pressupondo discussão teórica acerca da Ciência da Informação (CI e da Responsabilidade Social (RS.Metodologia: Análise de conteúdo, que favorece estudo quali-quantitativo a partir do estabelecimento de categorias. A análise das dissertações do Programa de Pós-Graduação em Ciência da Informação da Universidade Federal da Paraíba (PPGCI-UFPB acerca da temática RS permitiu nomear 13 agrupamentos.Resultados: O confronto entre teoria e apreciação das dissertações acata o pressuposto de que a CI como ciência essencialmente social mantém conceito sobre RS, embora não seja ele específico, e, sim, acompanhe as tendências contemporâneas, assumindo características da área da gestão. A Responsabilidade Social da Ciência da Informação volta-se, como maior frequência à promoção da cultura e a estudos sobre a função social das bibliotecas, o que corresponde à prática de uma Responsabilidade Social da Ciência da Informação voltada à Biblioteconomia. Eventualmente, isso pode se justificar pela incidência de dissertações apresentadas entre 1979 e 1987, quando o Programa mantinha área de concentração Sistemas de Bibliotecas Públicas.Conclusões: A responsabilidade social da Ciência da Informação é uma realidade, em termos mundiais, e, em especial, no Brasil, o que justifica sua inserção gradativa no Encontro Nacional de Pesquisa da Ciência da Informação, sob os auspícios da Associação Nacional de Pesquisa e

High-Performance Wireless via the Merger of CI Chip-Shaped DS-CDMA and Oscillating-Beam Smart Antenna Arrays

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Nassar Carl R

2004-01-01

Full Text Available We introduce a novel merger of direct sequence code division multiple access (DS-CDMA and smart antenna arrays. With regard to the DS-CDMA scheme, we employ carrier interferometry DS-CDMA (CI/DS-CDMA, a novel implementation of DS-CDMA where chips are decomposable into narrowband frequency components. With regard to the antenna array, we deploy the oscillating-beam smart array. Here, applying proper time-varying phases to the array elements, we create small movement (oscillation in the antenna array's pattern, while steering the antenna pattern main lobe to the position of the intended user. The oscillating antenna pattern creates a time-varying channel with a controllable coherence time. This, in turn, provides transmit diversity in the form of a time diversity gain at the mobile receiver side. At the receiver, three stages of combining are available: combining time components of the received signal within symbol duration (each experiencing a different fade to enhance performance via time diversity; combining frequency components which make up the CI/DS-CDMA chip to enhance the performance via frequency diversity; and combining across chips to eliminate the interfering users on the system. Merging CI/DS-CDMA with the oscillating-beam smart antenna at the base station, we achieve very high capacity via the merger of SDMA (available through directionality of the antenna array and code division multiple access (inherent in CI/DS-CDMA, and very high performance via the construction of receivers that exploit both transmit diversity and frequency diversity. We present the performance gains of the proposed merger.

Globalização: novo paradigma das ciências sociais

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Octavio Ianni

1994-08-01

Full Text Available As ciências sociais estão sendo desafiadas a pensar a globalização do mundo. No fim do século XX, quando se anuncia o XXI, elas se defrontam com os dilemas que se abrem com a globalização das coisas, gentes e idéias. Há processos e estruturas sociais, econômicos, políticos, culturais e outros que apenas começam a ser estudados. Além do que é local, nacional e regional, colocam-se problemas novos e fundamentais com a emergência da sociedade global. As fronteiras geográficas e históricas, culturais e civilizatórias parecem modificar-se em direções e formas surpreendentes. Indivíduo, grupo, classe, coletividade e povo são colocados diante de outros horizontes. O próprio pensamento científico é desafiado a elaborar conceitos e interpretações para dar conta de realidades pouco conhecidas. As teorias da globalização, que começam a ser esboçadas, revelam o empenho das ciências sociais em explicar o que há de novo no que vai pelo mundo.Social sciences are now being challenged to think on the world's globalization. At the end of the twentieth century and dawn of the twenty first, they are faced with the dilemas that open up with the globalization of things, people and ideas: There are social, economical, political, cultural and other processes and structures that are just begining to be studied. Besides what is local, national and regional, new and fundamental problems appear with the rising global society. The geographic, historical, cultural and civilizatorian limits seem to change in surprising ways and directions. The individual, group, class, colectivity and people are put before other horizons. The scientific thinking itself is called upon to elaborate concepts and interpretations to account for little known realities. The globalization theories that are just being sketched show the efforts of Social Sciences to explain what is new going on in the world.

Culturas das Ciências Naturais Cultures of Natural Sciences

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Maria Margaret Lopes

2005-12-01

Full Text Available Este artigo apresenta subsídios para o ensino de História das Ciências, considerando particularmente o campo da História da História Natural e das Ciências Naturais. Sem ser uma revisão completa da historiografia desses campos de conhecimento sobre o mundo natural, retoma alguns traços gerais desses longos processos de definição de campos disciplinares que se configuram desde a Renascença até o final do século XVIII. Considera diversas tradições culturais e historiográficas que contribuíram para os nossos entendimentos atuais, de como a História Natural do Renascimento foi abandonando seus antigos quadros conceituais, assumindo novas práticas e se constituindo nas tradições da História Natural do século XVIII. Comenta esses processos, em que tanto a Botânica, a Zoologia, a Mineralogia se individualizam como áreas de conhecimentos apoiadas em práticas locais e coleções globais, indo além de sua subordinação à utilidade médica; bem como suas organizações em áreas de conhecimento, por começarem a se colocar questões relativas à origem e à historicidade dos seres e processos naturais, dados os avanços das temáticas classificatórias e das discussões envolvendo temporalidades.This paper provides insights into the teaching of the History of Science, especially the field of the History of Natural History and Natural Sciences. Although not claiming to be a complete historiographic review of these areas of knowledge about the natural world, it outlines the general traits of the long process of definition of disciplines that were shaped from the Renaissance to the end of the XVIII century. It encompasses various cultural and historiographic traditions that contributed to our present understanding of how Renaissance Natural History abandoned its ancient conceptual frameworks and assumed new practices and shaped itself in the tradition of XVIII century Natural History. The paper comments on these processes by which

PORÓWNANIE WYBRANYCH WŁAŚCIWOŚCI ZAPRAW ŻYWICZNYCH ZAWIERAJĄCYCH ODPADOWE TWORZYWA SZTUCZNE

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Bernardeta DĘBSKA

Full Text Available Racjonalna gospodarka odpadami stanowi jeden z priorytetowych kierunków szeroko rozumianej ochrony środowiska. Fakt umiejętnego zagospodarowania odpadów jest także ważny w kontekście zrównoważonego rozwoju społeczeństw. Do odpadów wyjątkowo uciążliwych dla środowiska zaliczyć należy tworzywa sztuczne. Wzrastające nieustannie ilości tego typu odpadów powodują występowanie problemów zarówno ekologicznych, jak i gospodarczych, co związane jest ze słabą biodegradacją tworzyw. Odpady te zaczęto wykorzystywać do produkcji materiałów budowlanych. Badania nad zagospodarowaniem odpadów z tworzyw sztucznych prowadzone są obecnie w różnych ośrodkach naukowych na świecie. W literaturze można znaleźć opisy wykorzystania odpadów m.in. polietylenu i polipropylenu, styropianu, poliuretanów, poliwęglanu, poliamidu, czy poli(chlorku winylu, jako modyfikatorów betonów i zapraw cementowych. W niniejszym artykule przedstawiono wyniki porównania wybranych właściwości czterech serii zapraw żywicznych zawierających różne odpady tworzyw sztucznych tj.: polipropylen (PP, polietylen (PE, piankę poliuretanową (PU oraz ekspandowany polistyren (EPS. Odpady te pochodziły odpowiednio z kubków po jogurtach, pianki podkładowej pod panele, pianki montażowej oraz płyt styropianowych. Zostały one rozdrobnione i stanowiły częściowy zamiennik kruszywa w zaprawach epoksydowych. Zbadano takie właściwości zapraw, jak: wytrzymałość na zginanie i ściskanie, gęstość objętościowa oraz nasiąkliwość. Wskazano materiał odpadowy, umożliwiający otrzymanie zaprawy cechującej się najkorzystniejszymi wartościami oznaczonych parametrów. Na podstawie uzyskanych wyników badań stwierdzono, że nawet przy 20% substytucji piasku odpadami tworzyw sztucznych, można otrzymać kompozyt charakteryzujący się bardzo dobrymi parametrami wytrzymałościowymi oraz niską nasiąkliwością wodą.

O que é pesquisar - entre Deleuze-Guattari e o candomblé, pensando mito, ciência, arte e culturas de resistência

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Gauthier Jacques

1999-01-01

Full Text Available A ciência atual é uma ciência do evento e do acontecimento. Explorando, após Deleuze, a diferença entre evento e acontecimento na filosofia estóica, o autor caracteriza vários modos de "fazer ciência": a dupla captura, referida, numa visão transcultural, à divindade Ogum do candomblé; a maturação escura, referida à divindade Ossãe etc. Daí são discutidos, com base em Spinoza, a questão do local e do universal na construção do conhecimento, e com base em Michel Serres, o problema da articulação entre mito e ciência. A pesquisa de Graziela Rodrigues, "Bailarino-pesquisador-intérprete: Processo de formação", é tomada como exemplo de abordagem inovadora, transcultural e sociopoética. Uma pergunta conclui este artigo: será que a descolonização dos espíritos (e dos corpos passa pela criação de uma episteme transcultural?

A comunicação nas ciências da linguagem

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Geraldo Carlos do Nascimento

2002-06-01

Full Text Available Este trabalho situa a questão da comunicação na sua vertente relacionada com as ciências da linguagem, que ganham corpo, embora suas origens remontem a Saussure, a partir do ensaio de Roman Jakobson, Linguistic and Poetics (1960, no qual é apresentado um esquema básico da comunicação. As fragilidades deste esquema, ainda vinculado às noções da sociologia funcionalista (Laswell/Scharam, logo se fizeram notar, particularmente no que se refere à sua operacionalização; mas foi a partir de sua crítica, conforme se defende aqui, que a semiótica greimasiana pôde, ao articular comunicação e sentido, estabelecer bases mais consistentes para a discussão da noção de comunicação e se seu campo presumível.

Study for optimization of a 60 Co industrial irradiator of 250 k Ci

International Nuclear Information System (INIS)

Pina V, G.

1995-01-01

This work presents results of a benchmark between calculated and experimental absorbed dose values for a typical product, in a 60 Co industrial irradiator, located at ININ, Mexico. The goal of this work is to reach a ± 10 % approximation between both values. ININ 60 Co industrial irradiator is a two level, two layer system with overlapping product configuration, 56 irradiation positions with an activity of around 250 k Ci. Calculated values were obtained by QAD-CGGP code. This code uses a point kernel technique, build-up factors fitting was done by geometrical progression and combinatorial geometry was used for 3 D system description. Main code modifications were related with source simulation by punctual sources and energy spectrum (16 energy groups) and anisotropic emission were also considered. Experimental data were obtained from routine dosimetry which was done with red acrylic pellets; they were irradiated together the product in predetermined positions, for 36 maximum and minimum absorbed dose values. Typical product was polypropylene Petri dish packages, apparent density 0.13 g/cm 3 . It was chosen because regular geometry (2 packages per full irradiator container) and enough amount for considering homogeneous loading inside irradiation chamber. Required minimum dose was 15 kGy. Results showed a 8% variation between calculated and experimental values for maximum absorbed dose (18.2 kGy vs 16.8 kGy) and 3 % variation for minimum absorbed dose (13.8 kGy vs 14.3 kGy); these results fixed with the original proposal. (Author)

Przykład utraty stateczności ściany frontowej pozostawionej po rozebraniu kamienicy

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Janusz Laskowski

2018-04-01

Full Text Available W artykule przedstawiono opis ściany frontowej budynku pozostawionej po jego rozbiórce. Prowizoryczne zabezpieczenie tej ściany oraz wpływ czynników zewnętrznych, w tym geologicznych, przyczyniły się do utraty przez tę ścianę stateczności, co przy braku jakichkolwiek skutecznych zabezpieczeń może doprowadzić do katastrofy budowlanej.

Iodine status in late pregnancy and psychosocial determinants of iodized salt use in rural northern Viet Nam

Science.gov (United States)

Tran, Thach; Biggs, Beverley; Tran, Tuan; Dwyer, Terry; Casey, Gerard; Tho, Dang Hai; Hetzel, Basil

2011-01-01

Abstract Objective To establish iodine status among pregnant women in rural northern Viet Nam and explore psychosocial predictors of the use of iodized salt in their households. Methods This prospective study included pregnant women registered in health stations in randomly-selected communes in Ha Nam province. At recruitment ( 28 weeks of gestation) a urine specimen was collected to measure urinary iodine concentration (UIC) and iodized salt use was assessed. Predictors were explored through univariable analyses and multivariable linear and logistic regression. Findings The 413 pregnant women who provided data for this study had a median UIC of 70 µg/l; nearly 83% had a UIC lower than the 150 µg/l recommended by the World Health Organization; only 73.6% reported using iodized salt in any form in their households. Iodized salt use was lower among nulliparous women (odds ratio, OR: 0.56; 95% confidence interval, CI: 0.32–0.96); less educated women (OR: 0.34; 95% CI: 0.16–0.71); factory workers or small-scale traders (OR: 0.52; 95% CI: 0.31–0.86), government workers (OR: 0.35; 95% CI: 0.13–0.89) and women with common mental disorders at recruitment (OR: 0.61; 95% CI: 0.38–0.98). Conclusion The decline in the use of iodized salt in Viet Nam since the National Iodine Deficiency Disorders Control Programme was suspended in 2005 has placed pregnant women and their infants in rural areas at risk of iodine deficiency disorders. PMID:22084527

Jakość życia chorych z niewydolnością serca = Quality of life in patients with heart failure

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Beata Kowalczyk

2016-10-01

  Streszczenie: Wprowadzenie Przewlekła niewydolność serca jest poważnym problemem klinicznym, społecznym i ekonomicznym. W ostatnich latach częstość występowania tej choroby stale rośnie i znacząco ogranicza funkcjonowanie pacjentów w aspekcie bio-psycho-społecznym, obniżając poziom jego jakości życia. Cel pracy Ocena jakości życia pacjentów z niewydolnością serca. Materiał i metody Badaniem objęto 105 pacjentów z niewydolnością serca. Do jego przeprowadzenia wykorzystano anonimową ankietę własnego autorstwa, kwestionariusza AIS oraz kwestionariusza NHP. Przeprowadzono analizę statystyczną. Wyniki Najliczniejszą grupę stanowiły osoby ze średnim poziomem akceptacji choroby (56,2%. Najwięcej ankietowanych znajdowało się w II klasie w skali NYHA (56,2% i wykazywało średni i dobry (33 vs. 20 stopień akceptacji choroby. Analiza kwestionariusza NHP wykazała, iż w grupie pacjentów z dobrym poziomem akceptacji choroby poziom zaburzeń funkcji jest znacznie niższy niż w grupie pacjentów nie akceptujących chorobę (p<0,001. W grupie ankietowanych osób najbardziej zaburzona była energia życiowa (63,0 ± 42,2, a najmniej izolacja społeczna (20,0 ± 27,8. Wnioski Wyższy poziom jakości życia warunkuje lepszą akceptację choroby. Na stopień akceptacji choroby pacjentów wpływa: płeć, wiek, miejsce zamieszkania, stan cywilny, frakcja wyrzutowa lewej komory, klasa czynnościowa wg NYHA, konieczność wezwania pogotowia lub udania się na SOR, niektóre choroby współistniejące i wszystkie domeny jakości życia. Na akceptację choroby wpływają ujemnie ograniczenia ruchowe, wyobcowanie społeczne, reakcje emocjonalne i poziom energii.  Im niższa jakość życia tym niższy poziom akceptacji choroby. Słowa kluczowe: niewydolność serca, jakość życia, akceptacja choroby.           Abstract: Background Chronic heart failure is a serious clinical, social and economic problem.  In recent years, the

Ciência do Esporte no Brasil: reflexões sobre o desenvolvimento das pesquisas, o cenário atual e as perspectivas futuras

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Luís VIVEIROS

2015-03-01

Full Text Available O Brasil foi, recentemente, palco de um dos eventos esportivos mais importantes do mundo, a Copa do Mundo de Futebol de 2014 e, em um futuro próximo, irá sediar os Jogos Olímpicos de Rio 2016. Esses eventos podem ser considerados como uma grande oportunidade para desenvolver a Ciência do Esporte no Brasil. A Ciência do Esporte pode ser definida como o processo científico utilizado para orientar a prática do Esporte, com o objetivo, em última instância, de melhorar o desempenho esportivo. No entanto, apesar deste objetivo, o consenso geral é que aplicação do conhecimento gerado pela Ciência do Esporte na prática ainda é incipiente. Este ensaio revisita o modelo para o desenvolvimento da Ciência do Esporte, proposto anteriormente por Bishop(1 , discute o cenário da Ciência do Esporte no Brasil e também aponta para as perspectivas futuras. As diretrizes do modelo revisitado, em conjunto com as discussões realizadas neste ensaio, podem ajudar o cientista do Esporte a desenvolver estudos aplicados nos quais os resultados poderiam ser utilizados para orientar a prática e, possivelmente, maximizar o desempenho esportivo.

Factors Affecting the Presence of Adequately Iodized Salt at Home in Wolaita, Southern Ethiopia: Community Based Study.

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Kumma, Wondimagegn Paulos; Haji, Yusuf; Abdurahmen, Junayde; Mehretie Adinew, Yohannes

2018-01-01

Universal use of iodized salt is a simple and inexpensive method to prevent and eliminate iodine deficiency disorders like mental retardation. However, little is known about the level of adequately iodized salt consumption in the study area. Therefore, the study was aimed at assessing the proportion of households having adequately iodized salt and associated factors in Wolaita Sodo town and its peripheries, Southern Ethiopia. A cross-sectional study was conducted from May 10 to 20, 2016, in 441 households in Sodo town and its peripheries. Samples were selected using the systematic sampling technique. An iodometric titration method (AOAC, 2000) was used to analyze the iodine content of the salt samples. Data entry and analysis were done using Epi Info version 3.5.1 and SPSS version 16, respectively. The female to male ratio of the respondents was 219. The mean age of the respondents was 30.2 (±7.3 SD). The proportion of households having adequately iodized salt was 37.7%, with 95% CI of 33.2% to 42.2%. Not exposing salt to sunlight with [OR: 3.75; 95% CI: 2.14, 6.57], higher monthly income [OR: 3.71; 95% CI: 1.97-7.01], and formal education of respondents with [OR: 1.75; 95% CI: 1.14, 2.70] were found associated with the presence of adequately iodized salt at home. This study revealed low levels of households having adequately iodized salt in Wolaita Sodo town and its peripheries. The evidence here shows that there is a need to increase the supply of adequately iodized salt to meet the goal for monitoring progress towards sustainable elimination of IDD.

The Role of Journals in Building up Communities: The Experience of "Ciência em Tela"

Science.gov (United States)

Martins, Isabel; de Souza Barros, Susana

2015-01-01

"Ciência em Tela" is an open access Brazilian science teacher education online journal that has been published twice a year since 2008 and which encourages the participation of professionals with different backgrounds and the submission of a variety of textual genres, besides research papers. Another feature is that the journal includes…

Os Congressos Brasileiros de Ciências Sociais e Humanas em Saúde da Abrasco: um campo científico em disputa

Directory of Open Access Journals (Sweden)

Aurea Maria Zöllner Ianni

2015-02-01

Full Text Available Atualmente, no Brasil, configura-se um pensamento social em saúde, como campo científico, político e atuante: Estudar os Congressos de Ciências Sociais em Saúde da Abrasco representa realizar uma genealogia parcial da área, apreendendo como se deu a constituição desse subcampo e seu desenvolvimento, além de mapear o atual ‘estado da arte’ dessa área de conhecimento. Este artigo analisa as falas de informantes-chave sobre as realizações dos Congressos. São 13 entrevistas com presidentes da Abrasco e coordenadores das Comissões de Ciências Sociais, em diferentes gestões – anos de realização dos Congressos Brasileiros de Ciências Sociais e Humanas em Saúde, entre 1995 e 2011. Os depoimentos permitiram identificar três momentos marcantes da realização dos Congressos: o primeiro, em 1995, quando da realização do I Congresso, que significou a maturação do conhecimento das ciências sociais em saúde, a demarcação do campo; o III Congresso, de 2005, referido como o de consolidação da área de conhecimento, de consolidação desse campo científico; e o V Congresso, de 2011, que pôs em pauta o lugar científico das ciências sociais e humanas em saúde no contexto da Saúde Coletiva, no Brasil.

Polityka rachunkowości w praktyce jednostek gospodarczych w kontekście jej oceny przez biegłych rewidentów

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Katarzyna Świetla

2017-07-01

Full Text Available Ramowy charakter regulacji prawa bilansowego umożliwia jednostkom gospodarczym świadome prowadzenie polityki rachunkowości, które pozwala na kreowanie obrazu przedsiębiorstwa, a tym samym na realizację jego celów i założeń gospodarczych. W artykule, na podstawie analizy literatury przedmiotu i aktów prawnych przedstawiono współczesne problemy związane z tworzeniem polityki rachunkowości i jej dostosowywaniem do indywidualnych potrzeb jednostek gospodarczych. Zaprezentowano także wyniki badań ankietowych przeprowadzonych na grupie polskich biegłych rewidentów. W ich opinii jednostki gospodarcze częściej wykorzystują instrumenty polityki rachunkowości w celu świadomego i celowego kreowania obrazu przedsiębiorstwa, niż w rozmyślnym fałszowaniu sprawozdań finansowych. Autorzy zwracają uwagę na wzrost znaczenia zewnętrznych jednostek konsultingowych w tworzeniu i dostosowywaniu polityki rachunkowości do potrzeb jednostek. Przeprowadzone rozważania skłaniają także do zmiany postrzegania roli biegłego rewidenta w badaniu polityki rachunkowości. W opinii autorów, potwierdzonej wynikami badań, biegły rewident powinien nie tylko sprawdzać zgodność przyjętych rozwiązań z prawem bilansowym, ale też oceniać ich celowość i zasadność w konkretnej sytuacji danej jednostki.

Przestrzenne zróżnicowania kalendarza płodności we współczesnej Polsce

OpenAIRE

Szukalski, Piotr

2014-01-01

W każdym kraju występują regionalne różnice zachowań demograficznych, w tym i prokreacyjnych. Celem niniejszego artykułu jest wskazanie na podstawie analizy zmian rozkładów cząstkowych współczynników płodności w latach 1991-2012, czy w polskich realiach występuje stałość kalendarza płodności w poszczególnych województwach. Przeprowadzona analiza wskazuje, iż sytuacja taka występuje, przy czym można wyodrębnić 2 w miarę jednorodne grupy, obejmujące łącznie większość województw. W Polsce Północ...

A origem do universo como tema para discutir a Natureza da Ciência no Ensino Médio

Directory of Open Access Journals (Sweden)

Gustavo Antonio Montenegro Guttmann

2015-05-01

Full Text Available http://dx.doi.org/10.5007/2175-7941.2015v32n2p442 Nesse artigo, será apresentada uma proposta de introdução de questões relativas à Natureza da Ciência a partir da confrontação de duas teorias distintas sobre a origem do universo. Esse trabalho foi desenvolvido junto a turmas de Ensino Médio de uma escola do Rio de Janeiro. As teorias são divergentes, sendo uma defensora de um universo com uma origem definida, o Big Bang, e a outra de um Universo Eterno. Ao final do trabalho, foi possível aferir que os alunos passaram a ter uma visão mais complexa sobre Ciência.

Transforming growth factor β (CiTGF-β) gene expression is induced in the inflammatory reaction of Ciona intestinalis.

Science.gov (United States)

Vizzini, Aiti; Di Falco, Felicia; Parrinello, Daniela; Sanfratello, Maria Antonietta; Cammarata, Matteo

2016-02-01

Transforming growth factor (TGF-β) is a well-known component of a regulatory cytokines superfamily that has pleiotropic functions in a broad range of cell types and is involved, in vertebrates, in numerous physiological and pathological processes. In the current study, we report on Ciona intestinalis molecular characterisation and expression of a transforming growth factor β homologue (CiTGF-β). The gene organisation, phylogenetic tree and modelling supported the close relationship with the mammalian TGF suggesting that the C. intestinalis TGF-β gene shares a common ancestor in the chordate lineages. Functionally, real-time PCR analysis showed that CiTGF-β was transcriptionally upregulated in the inflammatory process induced by LPS inoculation, suggesting that is involved in the first phase and significant in the secondary phase of the inflammatory response in which cell differentiation occurs. In situ hybridisation assays revealed that the genes transcription was upregulated in the pharynx, the main organ of the ascidian immune system, and expressed by cluster of hemocytes inside the pharynx vessels. These data supported the view that CiTGF-β is a potential molecule in immune defence systems against bacterial infection. Copyright © 2015 Elsevier Ltd. All rights reserved.

Modified Stability Charts for Rock Slopes Based on the Hoek-Brown Failure Criterion / Zmodyfikowane Diagramy Stabilności Skalistych Zboczy Otrzymane W Oparciu O Warunek Wytrzymałości Hoeka-Browna

Science.gov (United States)

Nekouei, Mahdi; Ahangari, Kaveh

2013-09-01

Only an article rendered by Lia et al. in 2008 has represented charts based on Hoek-Brown criterion for rock slopes, however, these charts are not precise and efficient. Because of this problem, a modification is suggested for the mentioned charts in this study. The new charts are calculated according to four methods. Among the methods, one relates to finite element method using Phase2 software. The other three methods are Janbu, Bishop and Fellenius that belong to limit equilibrium method by using Slide software. For each slope angle, the method having high correlation coefficient is selected as the best one. Then, final charts are rendered according to the selected method and its specific equations. Among forty equations, twenty-five ones or 62.5% relate to numerical method and Phase2 software, six ones or 15% belong to Fellenius limit equilibrium, six ones or 15% relate to Bishop limit equilibrium, and three ones or 7.5% belong to Janbu limit equilibrium. In order to validate new charts, slope stability analysis is carried out for several sections of Chadormalu iron ore open pit mine, Iran. The error percentage of new charts in limit equilibrium method using Slide software and in Bishop method for slopes of Chadormalu iron ore mine are rendered and compared. The charts on a basis of Hoek-Brown failure criterion for rock slopes show less than ±4% error. This indicates that these charts are appropriate tools and their safety factor is optimal for rock slopes. Diagramy stabilności skalistych zboczy otrzymane w oparciu o warunek wytrzymałości Hoeka- Browna znaleźć można jedynie w pracy Lia et al. (2008), choć wykresy te nie są absolutnie dokładne i jasne. Dlatego też w niniejszym artykule zaproponowano pewną modyfikację diagramów. Nowe wykresu sporządzono w oparciu o cztery metody. Jedna z metod opiera się na metodzie elementów skończonych i wykorzystuje oprogramowanie Phase2. Pozostałe trzy podejścia to metody Janbu, Bishopa i Felleniusa bazuj

Gender-specific effects of caste and salt on hypertension in poverty: a population-based study.

Science.gov (United States)

Thrift, Amanda G; Evans, Roger G; Kalyanram, Kartik; Kartik, Kamakshi; Fitzgerald, Sharyn M; Srikanth, Velandai

2011-03-01

Little is known about the risk of developing hypertension in those living in poverty in rural India. We examined gender and caste influences on risk factors for hypertension in a disadvantaged rural community. In 1479 adults living in 12 hamlets in rural Andhra Pradesh, we measured blood pressure, height, weight, waist and hip girth, and used point-of-care devices to measure blood glucose, cholesterol, triglyceride and haemoglobin levels. Information about lifestyle habits was obtained by questionnaire. Multivariable backward stepwise logistic regression was used to determine factors associated with hypertension (blood pressure ≥ 140/90 mmHg). The mean age was 39.7 years; 46.2% were men, 11.4% were hypertensive, 0.8% were obese and 44.4% were underweight (BMI women. The association of caste was eliminated after adjustment for BMI in women [odds ratio (OR) 1.12; 95% confidence interval (CI) 0.61-2.06], but not in men (OR 2.93, 95% CI 1.77-4.86). Similar results were found for educational status. High salt intake was not associated with hypertension in women (OR 0.85, 95% CI 0.44-1.65), but was in men (OR 2.26, 95% CI 1.27-4.02). In this disadvantaged rural community, men are particularly prone to the effects of relative socioeconomic advantage and salt intake on the risk of hypertension. Traditional risk factors may play a greater role in the development of hypertension in men living in poverty than in women.

Visualization and prediction of porosity in roller compacted ribbonswith near infrared chemical imaging (NIR-CI)

DEFF Research Database (Denmark)

Khorasani, Milad Rouhi; Amigo Rubio, Jose Manuel; Sonnergaard, Jørn

2015-01-01

The porosity of roller compacted ribbon is recognized as an important critical quality attribute which has a huge impact on the final product quality. The purpose of this study was to investigate the use of near-infrared chemical imaging (NIR-CI) for porosity estimation of ribbons produced...... and control of continuously operating roller compaction line....

A meta-história de Hayden White: uma crítica construtiva à "ciência" histórica

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Paul Sutermeister

2009-06-01

Full Text Available Apresenta-se brevemente a teoria da história-narrativa de Hayden White, seus conceitos e críticas. Por analisar objetivamente a questão da verdade na historiografia, White contribuiu para uma conscientização, não só na ciência histórica mas também em outras áreas, sobre o dilema entre ciência e retórica. Trata-se de um dilema que mesmo os críticos mais severos de White, como o historiador Carlo Ginzburg, devem enfrentar. 

Ultrasonic assisted dyeing: dyeing of acrylic fabrics C.I. Astrazon Basic Red 5BL 200%.

Science.gov (United States)

Kamel, M M; Helmy, H M; Mashaly, H M; Kafafy, H H

2010-01-01

The dyeing of acrylic fabrics using C.I. Astrazon Basic Red 5BL 200% has been studied with both conventional and ultrasonic techniques. The effect of dye concentration, dye bath pH, ultrasonic power, dyeing time and temperature were studied and the resulting shades obtained by dyeing with both techniques were compared. Colour strength values obtained were found to be higher with ultrasonic than with conventional heating. The results of fastness properties of the dyed fabrics were studied. X-ray and Scanning Electron Microscope SEM were carried out on dyed samples using both methods of dyeing to find out an explanation for the better dyeability of acrylic fabrics with (US) method. Dyeing kinetics of acrylic fabrics using C.I. Astrazon Basic Red 5BL 200% using conventional and ultrasonic conditions were compared. The time/dye-uptake isotherms are revealing the enhanced dye-uptake in the second phase of dyeing. The values of dyeing rate constant, half-time of dyeing and standard affinity and ultrasonic efficiency have been calculated and discussed.

Aprendizagem baseada em problemas no ensino de ciências: Mudando atitudes de alunos e professores

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João Manoel da Silva Malheiro

2008-06-01

Full Text Available O aprendizado baseado em problemas (APB é apontado como ferramenta importante para ensinar os alunos a aprender com autonomia. O objetivo deste trabalho é comparar a forma habitual de ensinar Ciências e Biologia no Ensino Médio da Escola Pública com a metodologia da Aprendizagem Baseada em Problemas (ABP. Para tanto, dois Cursos de Férias frequentados por alunos e professores do ensino médio foram baseados na ABP e dedicados à redescoberta da anatomia do corpo de animais com estilos de vida contrastantes. Foram feitas análises qualitativas e quantitativas a partir de questionários aplicados antes e depois dos cursos a alunos e professores. Os resultados apontaram para maior motivação dos alunos e professores em ciências e biologia após os cursos de férias e para a possibilidade da utilização imediata da metodologia no ensino médio na escola pública a despeito das restrições atuais de infra-estrutura.

Wpływ głęboszowania na zmiany właściwości fizyko-wodnych gleby płowej

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Andrzej Bogdał

2014-12-01

Full Text Available Badania wpływu głęboszowania na właściwości fizyko-wodne zbitych gleb uprawnych wykonano na gruntach ornych w miejscowości Wojnowice, położonej na terenie powiatu raciborskiego w województwie śląskim. Podczas prac terenowych wykonano i opisano po jednej odkrywce glebowej na polu głęboszowanym i niegłęboszowanym. Z każdego poziomu genetycznego obu profili glebowych pobrano próby gleby o strukturze nienaruszonej i naruszonej. Przy obu odkrywkach w warstwie ornej i podornej pomierzono przepuszczalność gleby. W laboratorium oznaczono skład granulometryczny, wilgotność, zawartość próchnicy i charakterystyczne gęstości gleby oraz wyliczono porowatość ogólną. Analiza wyników badań wykazała, że głębokie spulchnianie gleb płowych powoduje zmniejszenie ich gęstości objętościowej oraz zwiększenie infiltracji i porowatości ogólnej. Stwierdzono również poprawę stosunków powietrzno-wodnych w profilu głęboszowanym – zwiększyła się tam zawartość powietrza glebowego, a zmniejszyło uwilgotnienie. Badania wykazały, że nawet po 20 miesiącach od wykonania zabiegów agromelioracyjnych ich wpływ na wykorzystanie potencjalnych zdolności retencyjnych gleby jest zauważalny, co w konsekwencji może prowadzić do łagodzenia skutków zjawisk ekstremalnych –susz i powodzi.

O sistemismo de Bunge como base teórica e metodológica para pesquisa em Ciência da Informação

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Luciana Mara Silva

2016-08-01

Full Text Available O objetivo do estudo é aprofundar aspectos epistemológicos da Ciência da Informação (CI a partir das contribuições do pensamento de Bunge. Justifica-se pela natureza interdisciplinar da CI e sua constante necessidade de interação com outras áreas de conhecimento. Trata-se de um ensaio teórico a partir da análise de conceitos da área de CI e a proposta sistemista de Bunge. O estudo é complementado com a aplicação dos fundamentos do sistemismo em pesquisas sistemistas, uma descritiva e outra explicativa, sobre repositórios institucionais de acesso aberto, exemplificando a condução de pesquisa sob a operação epistêmica fundamental do sistemismo: a redução ao sistema.

A biotechnological project with a gamma radiation source of 100,000 Ci

International Nuclear Information System (INIS)

Lombardo, J.H.; Smolko, E.E.

1990-01-01

A project for the production of radiovaccines and other bio-medical products is presented which includes a radiation facility provided with a gamma ray source equivalent to 100,000 Ci of Co-60. The whole process incorporates novel basic features in virus production and inactivation steps. The former is carried out in animals previously subjected to immunodepression through electromagnetic radiation. The latter is obtained at low temperatures by using either electromagnetic or particle radiations. A vaccine manufacture process is shown to illustrate the utilization of ionizing radiations to obtain a foot and mouth disease virus (FMDV) vaccine with good antigenic quality and low cost. (author)

The eclipse of CI Cygni in 1980 on the objective prism spectra

International Nuclear Information System (INIS)

Mikolajewska, J.; Mikolajewski, M.

1982-01-01

The observations of CI Cyg were carried out with the Torun 60/90 cm Schmidt telescope with the objective prism giving a dispersion of 250 A/mm at H-gamma. Intensity traces of 20 selected spectra, made on the Kodak IIa-O plates, were made. The results were corrected for all instrumental effects and the interstellar extinction. The relative emission lines intensities have been obtained from the tracings after normalization to H-beta = 100. The spectra were typical for the quiet symbiotic star. So, all changes in the spectrum were caused by geometrical effects (eclipse). A preliminary analysis of the obtained spectra is presented. (Auth.)

Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP

DEFF Research Database (Denmark)

Lundby, Alicia; Akemann, Walther; Knöpfel, Thomas

2010-01-01

A voltage sensitive phosphatase was discovered in the ascidian Ciona intestinalis. The phosphatase, Ci-VSP, contains a voltage-sensing domain homologous to those known from voltage-gated ion channels, but unlike ion channels, the voltage-sensing domain of Ci-VSP can reside in the cell membrane...... as a monomer. We fused the voltage-sensing domain of Ci-VSP to a pair of fluorescent reporter proteins to generate a genetically encodable voltage-sensing fluorescent probe, VSFP2.3. VSFP2.3 is a fluorescent voltage probe that reports changes in membrane potential as a FRET (fluorescence resonance energy....... Neutralization of an arginine in S4, previously suggested to be a sensing charge, and measuring associated sensing currents indicate that this charge is likely to reside at the membrane-aqueous interface rather than within the membrane electric field. The data presented give us insights into the voltage-sensing...

A história da ciência na prática de professores portugueses: implicações para a formação de professores de ciências The history of science in portuguese teachers' practice: implications for science teachers education

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Maria da Conceição Duarte

2004-12-01

Full Text Available O reconhecimento das limitações da educação científica tradicional para atuar numa sociedade que se reclama, cada vez mais, como "sociedade da informação e do conhecimento" conduziu à retomada da discussão sobre a necessidade de inovar e produzir novos currículos e novas formas de ensinar ciências. Esta idéia vai atravessar diferentes culturas e países, nomeadamente Portugal, conduzindo a importantes reformas ou reorganizações curriculares, onde a História da Ciência aparece como uma dimensão importante na promoção da cidadania e do conhecimento das ciências como cultura. Mas estarão os professores preparados para enfrentar esse novo desafio? Neste artigo procuraremos dar uma resposta a esta questão, com base tanto em resultados de estudos realizados em que se procurou investigar as práticas de professores portugueses e suas percepções relativamente à sua formação e à importância conferida à História da Ciência, quanto na análise dos currículos de formação de professores de ciências. Com base nesses resultados serão retiradas algumas implicações para a formação de professores.There are limitations of traditional Science Education in a society that more and more claims to be a "society of information and knowledge". It brings back the discussion about the need to innovate and produce new curricula and new approaches for science teaching. This idea will cross different cultures and countries, namely Portugal, leading to important curricular reforms or reorganizations, where the History of Science appears as an important dimension of the promotion of citizenship and of scientific knowledge as culture. But the following question arises: Are teachers prepared to face the new challenge? In this article we will try to give an answer to this question, building on results of research studies focused on Portuguese teachers' practices, their perceptions about their education and the importance they attach to the

Near-infrared chemical imaging (NIR-CI) of 3D printed pharmaceuticals

DEFF Research Database (Denmark)

Khorasani, Milad; Edinger, Magnus; Raijada, Dharaben Kaushikkumar

2016-01-01

Hot-melt extrusion and 3D printing are enabling manufacturing approaches for patient-centred medicinal products. Hot-melt extrusion is a flexible and continuously operating technique which is a crucial part of a typical processing cycle of printed medicines. In this work we use hot-melt extrusion...... for manufacturing of medicinal films containing indomethacin (IND) and polycaprolactone (PCL), extruded strands with nitrofurantoin monohydrate (NFMH) and poly (ethylene oxide) (PEO), and feedstocks for 3D printed dosage forms with nitrofurantoin anhydrate (NFAH), hydroxyapatite (HA) and poly (lactic acid) (PLA......). These feedstocks were printed into a prototype solid dosage form using a desktop 3D printer. These model formulations were characterized using near-infrared chemical imaging (NIR-CI) and, more specifically, the image analytical data were analysed using multivariate curve resolution-alternating least squares (MCR...

Skład kwasów tłuszczowych i twardość czekolad gorzkich o różnej zawartości miazgi kakaowej = Fatty acid composition and hardness of dark chocolates with different content of cacao mass

Directory of Open Access Journals (Sweden)

Renata Taradejna

2015-09-01

Wydział Nauki o Żywności, Uniwersytet Warmińsko-Mazurski w Olsztynie     Uniwersytet Warmińsko-Mazurski w Olsztynie Katedra Przetwórstwa i Chemii Surowców Roślinnych Pl. Cieszyński 1, 10-726 Olsztyn e-mail: beata.wronowska@uwm.edu.pl     Abstrakt W pracy analizowano zróżnicowanie dostępnych na rynku czekolad gorzkich pod względem składu kwasów tłuszczowych oraz twardości. Materiałem badawczym było 14 czekolad gorzkich pochodzących od różnych firm o zawartości miazgi kakaowej od 45% do 90%. Skład kwasów tłuszczowych oznaczono chromatograficznie, a twardość zmierzono w teście łamania za pomocą uniwersalnej maszyny testującej. Wykazano, że 6 czekolad zawierało w swoim składzie poniżej 65% miazgi kakaowej, nie spełniając wymagań określonych w polskiej normie dla czekolady gorzkiej. Pomimo tego, prawie wszystkie czekolady miały skład kwasów tłuszczowych typowy dla tłuszczu kakaowego; udziały kwasów oleinowego, stearynowego i palmitynowego wynosiły odpowiednio: 31,2-33,1%, 34,1-36,8% i 25,5-29,0%. Tylko w przypadku jednej czekolady stwierdzono wyższy udział kwasu palmitynowego (33,8%, natomiast niższy kwasów oleinowego i stearynowego (odpowiednio 29,4% i 32,9%. Badane czekolady gorzkie cechowały się zróżnicowaną twardością, na co wskazywały wartości siły kształtujące się w szerokim zakresie (24,2-85,6 N. Nie zaobserwowano zależności pomiędzy składem kwasów tłuszczowych a wartością siły potrzebnej do złamania kostki czekolady.   Słowa kluczowe: czekolada gorzka, miazga kakaowa, kwasy tłuszczowe, twardość.       Abstract The study analysed the diversity of commercially available dark chocolate in terms of fatty acid composition and hardness. The research material was 14 bitter chocolate from different companies about the content of cocoa mass from 45% to 90%. The fatty acid composition was determined by chromatography, and the hardness measured by the breaking test with the universal

“Para mulheres na ciência”: uma análise do programa da L’Oréal

Directory of Open Access Journals (Sweden)

Fabiani Figueiredo Caseira

2016-01-01

Full Text Available O presente artigo tem como objetivo investigar premiação da L’Oréal “Para Mulheres na Ciência”. Esta pesquisa se fundamenta a partir do campo teórico dos estudos feministas e de gênero, na sua vertente pós-estruturalista. Os dados de análise serão produzidos a partir da página da premiação, bem como alguns excertos presentes nos sites das parcerias ABC e UNESCO. As análises estarão ancoradas em algumas ferramentas da análise do discurso em Foucault. Nas análises tecidas buscamos algumas condições que possibilitaram a emergência dessa premiação e os discursos produzidos acerca das mulheres na ciência.

A treatment for a chronic stroke patient with a plegic hand combining CI therapy with conventional rehabilitation procedures: case report.

Science.gov (United States)

Bowman, Mary H; Taub, Edward; Uswatte, Gitendra; Delgado, Adriana; Bryson, Camille; Morris, David M; McKay, Staci; Mark, Victor W

2006-01-01

Constraint-Induced Movement therapy (CI therapy) is a recognized rehabilitation approach for persons having stroke with mild to moderately severe motor upper extremity deficits. To date, no rehabilitation treatment protocol has been proven effective that addresses both motor performance and spontaneous upper extremity use in the life situation for chronic stroke participants having severe upper extremity impairment with no active finger extension or thumb abduction. This case report describes treatment of a chronic stroke participant with a plegic hand using a CI therapy protocol that combines CI therapy with selected occupational and physical therapy techniques. Treatment consisted of six sessions of adaptive equipment and upper extremity orthotics training followed by a three-week, six-hour daily intervention of CI therapy plus neurodevelopmental treatment. Outcome measures included the Motor Activity Log for very low functioning patients (Grade 5 MAL), upper extremity portion of the Fugl-Meyer Motor Assessment, Graded Wolf Motor Function Test - for very low functioning patients (gWMFT- Grade 5), and Modified Ashworth Scale. The participant showed improvement on each outcome measure with the largest improvement on the Grade 5 MAL. In follow-up, the participant had good retention of his gains in motor performance and use of his more affected arm for real world activities after 3 months; after a one-week brush-up at 3 months, and at one year post-treatment.

Biophysical characterization of the fluorescent protein voltage probe VSFP2.3 based on the voltage-sensing domain of Ci-VSP.

Science.gov (United States)

Lundby, Alicia; Akemann, Walther; Knöpfel, Thomas

2010-11-01

A voltage sensitive phosphatase was discovered in the ascidian Ciona intestinalis. The phosphatase, Ci-VSP, contains a voltage-sensing domain homologous to those known from voltage-gated ion channels, but unlike ion channels, the voltage-sensing domain of Ci-VSP can reside in the cell membrane as a monomer. We fused the voltage-sensing domain of Ci-VSP to a pair of fluorescent reporter proteins to generate a genetically encodable voltage-sensing fluorescent probe, VSFP2.3. VSFP2.3 is a fluorescent voltage probe that reports changes in membrane potential as a FRET (fluorescence resonance energy transfer) signal. Here we report sensing current measurements from VSFP2.3, and show that VSFP2.3 carries 1.2 e sensing charges, which are displaced within 1.5 ms. The sensing currents become faster at higher temperatures, and the voltage dependence of the decay time constants is temperature dependent. Neutralization of an arginine in S4, previously suggested to be a sensing charge, and measuring associated sensing currents indicate that this charge is likely to reside at the membrane-aqueous interface rather than within the membrane electric field. The data presented give us insights into the voltage-sensing mechanism of Ci-VSP, which will allow us to further improve the sensitivity and kinetics of the family of VSFP proteins.