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Sample records for sak gerda raidaru

  1. The Banach-Saks index

    International Nuclear Information System (INIS)

    Semenov, E M; Sukochev, F A

    2004-01-01

    The properties of the Banach-Saks index are studied in the class of rearrangement invariant spaces. The Banach-Saks indices of the spaces L p,q and some Orlicz spaces are calculated. Generalizations of the Banach-Saks theorems are obtained.

  2. The Banach-Saks Property of the Banach Product Spaces

    OpenAIRE

    Jiang, Zhenglu; Fu, Xiaoyong

    2007-01-01

    In this paper we first take a detail survey of the study of the Banach-Saks property of Banach spaces and then show the Banach-Saks property of the product spaces generated by a finite number of Banach spaces having the Banach-Saks property. A more general inequality for integrals of a class of composite functions is also given by using this property.

  3. LArGe. A liquid argon scintillation veto for GERDA

    International Nuclear Information System (INIS)

    Heisel, Mark

    2011-01-01

    LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for possible applications in the GERDA experiment. GERDA searches for the neutrinoless double-beta decay in 76 Ge, by operating naked germanium detectors submersed into 65 m 3 of liquid argon. Similarly, LArGe runs Ge-detectors in 1 m 3 (1.4 tons) of liquid argon, which in addition is instrumented with photomultipliers to detect argon scintillation light. The light is used in anti-coincidence with the germanium detectors, to effectively suppress background events that deposit energy in the liquid argon. This work adresses the design, construction, and commissioning of LArGe. The background suppression efficiency has been studied in combination with a pulse shape discrimination (PSD) technique for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10 3 have been achieved. First background data of LArGe (without PSD) yield a background index of (0.12-4.6).10 -2 cts/(keV.kg.y) (90% c.l.), which is at the level of the Gerda phase I design goal. Furthermore, for the first time we measure the natural 42 Ar abundance (in parallel to Gerda), and have indication for the 2νββ-decay in natural germanium. (orig.)

  4. LArGe. A liquid argon scintillation veto for GERDA

    Energy Technology Data Exchange (ETDEWEB)

    Heisel, Mark

    2011-04-13

    LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for possible applications in the GERDA experiment. GERDA searches for the neutrinoless double-beta decay in {sup 76}Ge, by operating naked germanium detectors submersed into 65 m{sup 3} of liquid argon. Similarly, LArGe runs Ge-detectors in 1 m{sup 3} (1.4 tons) of liquid argon, which in addition is instrumented with photomultipliers to detect argon scintillation light. The light is used in anti-coincidence with the germanium detectors, to effectively suppress background events that deposit energy in the liquid argon. This work adresses the design, construction, and commissioning of LArGe. The background suppression efficiency has been studied in combination with a pulse shape discrimination (PSD) technique for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10{sup 3} have been achieved. First background data of LArGe (without PSD) yield a background index of (0.12-4.6).10{sup -2} cts/(keV.kg.y) (90% c.l.), which is at the level of the Gerda phase I design goal. Furthermore, for the first time we measure the natural {sup 42}Ar abundance (in parallel to Gerda), and have indication for the 2{nu}{beta}{beta}-decay in natural germanium. (orig.)

  5. Kelder. Gerda Taljaard. Kaapstad: Tafelberg, 2012. 224 pp. ISBN ...

    African Journals Online (AJOL)

    hoofkarakters of Gerda Taljaard's second novel. Kelder. One stole her child from another wo- man and the other ... Taljaard chose a very tricky topic for her second novel. There is namely still quite a rigid discourse of ... Furthermore, Taljaard also pre- sents the reader with a gay fashion designer dressed in leather shorts and ...

  6. Results on neutrinoless double beta decay from GERDA phase I

    CERN Multimedia

    CERN. Geneva

    2013-01-01

    After motivating searches of double beta decay and lepton number violation details about the construction, operation and analysis of GERDA will be given. Results of the recently completed phase I of data taking will then be presented and interpreted. Finally an outlook on future plans will be given.

  7. Germanium detector studies in the framework of the GERDA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Budjas, Dusan

    2009-05-06

    The GERmanium Detector Array (GERDA) is an ultra-low background experiment under construction at Laboratori Nazionali del Gran Sasso. GERDA will search for {sup 76}Ge neutrinoless double beta decay with an aim for 100-fold reduction in background compared to predecessor experiments. This ambition necessitates innovative design approaches, strict selection of low-radioactivity materials, and novel techniques for active background suppression. The core feature of GERDA is its array of germanium detectors for ionizing radiation, which are enriched in {sup 76}Ge. Germanium detectors are the central theme of this dissertation. The first part describes the implementation, testing, and optimisation of Monte Carlo simulations of germanium spectrometers, intensively involved in the selection of low-radioactivity materials. The simulations are essential for evaluations of the gamma ray measurements. The second part concerns the development and validation of an active background suppression technique based on germanium detector signal shape analysis. This was performed for the first time using a BEGe-type detector, which features a small read-out electrode. As a result of this work, BEGe is now one of the two detector technologies included in research and development for the second phase of the GERDA experiment. A suppression of major GERDA backgrounds is demonstrated, with (0.93{+-}0.08)% survival probability for events from {sup 60}Co, (21{+-}3)% for {sup 226}Ra, and (40{+-}2)% for {sup 228}Th. The acceptance of {sup 228}Th double escape events, which are analogous to double beta decay, was kept at (89{+-}1)%. (orig.)

  8. A Reflective Conversation with Ugur Sak: Gifted Education in Turkey

    Science.gov (United States)

    Shaughnessy, Michael F.; Sak, Ugur

    2015-01-01

    In this reflective conversation, Ugur Sak discusses the current "state of the art" of gifted education in Turkey. He reviews the use of enrichment, discusses acceleration and reviews curricular procedures in Turkey. He responds to questions about the identification of gifted students and discusses the age old debate of talent versus…

  9. Rainer Saks : ärgem lohutagem end lootusega, et Herman Simm oli ainus / Rainer Saks ; interv. Rasmus Kagge

    Index Scriptorium Estoniae

    Saks, Rainer

    2008-01-01

    Intervjuu Eesti eriteenistuste endise esikoordinaatori ning praeguse Vabariigi Presidendi kantselei direktoriga, kes vastab küsimustele, mis puudutavad Herman Simmi. Ta möönab, et ei ole põhjust arvata, nagu võiks riigireetmises kahtlustatav Herman Simm olla ainuke, kes riiki petta oskas. Vt. Kes on Rainer Saks?; Kes on Mitrohhin?

  10. Rainer Saks : ärgem lohutagem end lootusega, et Herman Simm oli ainus / Rainer Saks ; interv. Rasmus Kagge

    Index Scriptorium Estoniae

    Saks, Rainer

    2008-01-01

    Intervjuu Eesti eriteenistuste endise esikoordinaatori ning praeguse Vabariigi Presidendi kantselei direktoriga, kes vastab küsimustele riigireetmises kahtlustatava Herman Simmi kohta. Vt. samas: Kes on Rainer Saks? Lühiülevaade elukäigust ja karjäärist

  11. Status report of the Gerda Phase II startup

    Science.gov (United States)

    D'Andrea, Valerio; Gerda Collaboration

    2017-01-01

    The GERmanium Detector Array (GERDA) experiment, located at the Laboratori Nazionali del Gran Sasso (LNGS) of INFN, searches for 0νββ of 76Ge . Germanium diodes enriched to ˜ 86 % in the double beta emitter 76Ge ( enrGe are exposed being both source and detector of 0νββ decay. This process is considered a powerful probe to address still open issues in the neutrino sector of the (beyond) Standard Model of particle Physics. Since 2013, at the completion of the first experimental phase (Phase I), the GERDA setup has been upgraded to perform its next step (Phase II). The aim is to reach a sensitivity to the 0νββ decay half-life larger than 10^{26} yr in about 3 years of physics data taking, exposing a detector mass of about 35 kg of enrGe with a background index of about 10^{-3} cts/(keV . kg . yr). One of the main new implementations is the liquid argon (LAr) scintillation light read-out, to veto those events that only partially deposit their energy both in Ge and in the surrounding LAr. In this paper the GERDA Phase II expected goals, the upgraded items and few selected features from the first 2016 physics and calibration runs will be presented. The main Phase I achievements will be also reviewed.

  12. Sakārtojuma nevienādības

    OpenAIRE

    Popmane, Daiga

    2008-01-01

    Darbā tiek apskatīta viena no nevienādību teorijas sastāvdaļām – sakārtojuma nevienādības, kā arī daži to lietojumi. Darbā ir aplūkoti arī vairāki uzdevumi no dažādu gadu matemātikas olimpiādēm.

  13. Design, simulation and construction of the GERDA-muon veto; Design, Simulation und Aufbau des GERDA-Myonvetos

    Energy Technology Data Exchange (ETDEWEB)

    Knapp, Markus Alexander

    2009-10-09

    The GERmanium Detector Array (Gerda) is a experiment searching for the neutrinoless double beta decay of {sup 76}Ge. This very rare weakly interacting process is predicted to occur if the neutrino exhibits a mass and is a Majorana particle; i.e. it is its own antiparticle. Although the double beta decay with emission of two neutrinos has been found in several nuclei, there is at this moment only a part of the Heidelberg-Moscow Collaboration claiming to have observed the neutrinoless double beta decay. The best limit for the half life currently is T{sub 1/2} > 1.2.10{sup 25} y. Gerda will expose about 15 kg.y of enriched germanium detectors from the Heidelberg-Moscow and IGEX crystals in phase I. In this phase, it will be able to test the claim within one year, due to reduced background by a factor 10. In phase II about 100 kg.y of data will be accumulated, leading to T{sub 1/2} > 2.10{sup 26} y due to an additional reduction of the background by a factor of 10. For a high sensitivity at these half lives, it is necessary to detect the corresponding rare events. Therefore background reduction to a rate of 10{sup -3} (counts)/(keV.kg.year) is of utmost importance. Therefore different background identification methods, like pulseshape analysis or a muon veto will be used. In this work, the development of the Cherenkov muon veto detectors is presented. First design studies will be shown, including extensive Monte-Carlo simulations. These simulations were also used to optimize the trigger conditions of the data acquisition, to detect all muons, that cause an energy deposition in the germanium detectors. Finally the on site construction at the Laboratori Nazionali del Gran Sasso in Italy will be described. (orig.)

  14. Penyusunan Laporan Keuangan Berbasis SAK ETAP Koperasi Intako Dan Respon Pihak Eksternal

    OpenAIRE

    Indawatika, Feri

    2017-01-01

    This study aims to perform the preparation of financial statements in Cooperative INTAKO based SAK ETAP responses and identify external parties regarding the preparation of the financial statements based SAK ETAP.  This type of research is qualitative. Data collection techniques with interviews, documentation, and triangulation. Test the validity of the data by using the test of credibility, transferability, and dependability. Engineering analysis using the data collection phase, data reducti...

  15. Improvement of the energy resolution via an optimized digital signal processing in GERDA Phase I

    International Nuclear Information System (INIS)

    Agostini, M.; Bode, T.; Budjas, D.; Janicsko Csathy, J.; Lazzaro, A.; Schoenert, S.; Allardt, M.; Domula, A.; Lehnert, B.; Schneider, B.; Wester, T.; Wilsenach, H.; Zuber, K.; Bakalyarov, A.M.; Belyaev, S.T.; Lebedev, V.I.; Zhukov, S.V.; Balata, M.; D'Andrea, V.; Di Vacri, A.; Junker, M.; Laubenstein, M.; Macolino, C.; Zavarise, P.; Barabanov, I.; Bezrukov, L.; Doroshkevich, E.; Fedorova, O.; Gurentsov, V.; Kazalov, V.; Kuzminov, V.V.; Lubsandorzhiev, B.; Moseev, P.; Selivanenko, O.; Veresnikova, A.; Yanovich, E.; Barros, N.; Baudis, L.; Benato, G.; Walter, M.; Bauer, C.; Heisel, M.; Heusser, G.; Hofmann, W.; Kihm, T.; Kirsch, A.; Knoepfle, K.T.; Lindner, M.; Maneschg, W.; Salathe, M.; Schreiner, J.; Schwingenheuer, B.; Simgen, H.; Smolnikov, A.; Stepaniuk, M.; Wagner, V.; Wegmann, A.; Becerici-Schmidt, N.; Caldwell, A.; Liao, H.Y.; Majorovits, B.; Palioselitis, D.; Schulz, O.; Vanhoefer, L.; Bellotti, E.; Belogurov, S.; Kornoukhov, V.N.; Bettini, A.; Brugnera, R.; Garfagnini, A.; Hemmer, S.; Medinaceli, E.; Sada, C.; Sturm, K. von; Borowicz, D.; Brudanin, V.; Egorov, V.; Kochetov, O.; Nemchenok, I.; Rumyantseva, N.; Zhitnikov, I.; Zinatulina, D.; Cattadori, C.; Chernogorov, A.; Demidova, E.V.; Kirpichnikov, I.V.; Vasenko, A.A.; Falkenstein, R.; Freund, K.; Grabmayr, P.; Hegai, A.; Jochum, J.; Schmitt, C.; Schuetz, A.K.; Frodyma, N.; Misiaszek, M.; Panas, K.; Pelczar, K.; Wojcik, M.; Zuzel, G.; Gangapshev, A.; Gusev, K.; Hult, M.; Lutter, G.; Inzhechik, L.V.; Klimenko, A.; Lippi, I.; Stanco, L.; Ur, C.A.; Lubashevskiy, A.; Pandola, L.; Pullia, A.; Riboldi, S.; Shirchenko, M.

    2015-01-01

    An optimized digital shaping filter has been developed for the Gerda experiment which searches for neutrinoless double beta decay in 76 Ge. The GERDA Phase I energy calibration data have been reprocessed and an average improvement of 0.3 keV in energy resolution (FWHM) corresponding to 10% at the Q value for 0νββ decay in 76 Ge is obtained. This is possible thanks to the enhanced low-frequency noise rejection of this Zero Area Cusp (ZAC) signal shaping filter. (orig.)

  16. PENGARUH PEMBELAJARAN AKUNTANSI BERBASIS SAK IFRS DAN SELF-EFFICACY TERHADAP KESIAPAN MAHASISWA MENJADI GURU AKUNTANSI

    Directory of Open Access Journals (Sweden)

    Raeni Raeni

    2013-06-01

    Full Text Available The research was inspired by students’ readiness to be Accounting teachers with the rapid progress of science and technology and also free-market for workers. The objective of the study was to test the influence of Accounting learning based on SAK IFRS and self-efficacy toward students’ readiness to be Accounting teachers. The population of the research were Accounting education students in classess of 2010 until 2012. Thus, it used proportionate stratified random sampling. The respondents were 85 students in class 2010, 123 students in class 2011 and 154 students in class 2012. Then, the data were analyzed by percentage descriptive and doubled linear regression. The result of regression analysis showed that 1 Accounting learning based on SAK IFRS and self-efficacy contibuted positively and significantly for 52.4% toward students’ readiness to be Accounting students, 2 there was a positive and significant influence of Accounting learning based on SAK IFRS for 26.2% toward students’ readiness to be Accounting teachers, 3 there was a positive and significant influence of self-efficacy for 16.32% toward students’ readiness to be Accounting teachers. The familiarity level for learning Accounting based on SAK IFRS was high with the progress of science and technology and also full adoption from IFRS.

  17. Signal and background studies for the search of neutrinoless double beta decay in GERDA

    International Nuclear Information System (INIS)

    Agostini, Matteo

    2013-01-01

    The GERDA experiment searches for the neutrinoless double beta decay in Ge-76, by operating bare HPGe detectors in ultra-pure liquid Ar. This dissertation presents a first decomposition of the background measured in the current data-taking phase. The background at the energy of interest was found to be dominated by 214 Bi, 208 Tl and 42 K gamma-rays, with secondary contributions from 42 K and 214 Bi beta-rays, and 210 Po alpha-rays. For the forthcoming upgrade of the apparatus, a new HPGe detector design (BEGe) has been studied, with focus on its capability of suppressing the identified backgrounds through pulse shape analysis. This included the development of a comprehensive modeling of the detectors and the experimental characterization of their response to surface interactions. The achieved results show that GERDA can improve the present limit on the neutrinoless double beta decay half-life by an order of magnitude.

  18. A Myb transcription factor of Phytophthora sojae, regulated by MAP kinase PsSAK1, is required for zoospore development.

    Directory of Open Access Journals (Sweden)

    Meng Zhang

    Full Text Available PsSAK1, a mitogen-activated protein (MAP kinase from Phytophthora sojae, plays an important role in host infection and zoospore viability. However, the downstream mechanism of PsSAK1 remains unclear. In this study, the 3'-tag digital gene expression (DGE profiling method was applied to sequence the global transcriptional sequence of PsSAK1-silenced mutants during the cysts stage and 1.5 h after inoculation onto susceptible soybean leaf tissues. Compared with the gene expression levels of the recipient P. sojae strain, several candidates of Myb family were differentially expressed (up or down in response to the loss of PsSAK1, including of a R2R3-type Myb transcription factor, PsMYB1. qRT-PCR indicated that the transcriptional level of PsMYB1 decreased due to PsSAK1 silencing. The transcriptional level of PsMYB1 increased during sporulating hyphae, in germinated cysts, and early infection. Silencing of PsMYB1 results in three phenotypes: a no cleavage of the cytoplasm into uninucleate zoospores or release of normal zoospores, b direct germination of sporangia, and c afunction in zoospore-mediated plant infection. Our data indicate that the PsMYB1 transcription factor functions downstream of MAP kinase PsSAK1 and is required for zoospore development of P. sojae.

  19. Kompuroiden korporatismissa, : Eheytyneen SAK:n ristipaineet suomalaisessa korporatismissa 1968-1978

    OpenAIRE

    Savtschenko, Ritva

    2015-01-01

    Summary The study takes a look at the factors that influenced the operating culture of the Central Organization of Finnish Trade Unions (SAK) during the first decade of incomes policy from the point of view of corporatism. The effects of the corporatist system are studied from the perspective of co-operation, resistance and democracy. The theoretical part looks at the relationship between the theory of corporatism and the trade union movement. The empirical part looks at the effect of th...

  20. Aplikasi Penyusunan Laporan Keuangan Berbasis SAK Etap Pada Bagus Agriseta Mandiri

    Directory of Open Access Journals (Sweden)

    Mega Indah Puspita Sari

    2016-03-01

    Full Text Available The purpose of this study is to analyze the arrangement of existing financial report in Bagus Agriseta Mandiri and to conduct the implementation of financial report arrangement that is suitable with SAK ETAP in UKM Bagus Agriseta Mandiri. In this study, the researcher uses case study or field study research that is aimed to learn intensively on the background of problems, situation and the position of the event occurs in nowadays, to solve the problems occurs in company, also the environmental interaction of current social unit in its way (given. The result of this study shows that company only makes loss and profit report, but in its presentation, it still not appropriate with SAK ETAP and financial balance report, cash flow and company equity is not presented yet because of the company less comprehending the standard of arranging financial report. By the existence of SAK ETAP it is expected to create the uniformity in implementing accounting treatment and the presentation of financial report so that it can result appropriate information toward the need of users.

  1. Limit on the radiative neutrinoless double electron capture of 36Ar from GERDA Phase I

    International Nuclear Information System (INIS)

    Agostini, M.; Balata, M.; D'Andrea, V.; Di Vacri, A.; Junker, M.; Laubenstein, M.; Allardt, M.; Domula, A.; Lehnert, B.; Schneider, B.; Wester, T.; Wilsenach, H.; Zuber, K.; Bakalyarov, A.M.; Belyaev, S.T.; Lebedev, V.I.; Zhukov, S.V.; Barabanov, I.; Bezrukov, L.; Doroshkevich, E.; Fedorova, O.; Gurentsov, V.; Kazalov, V.; Kuzminov, V.V.; Lubsandorzhiev, B.; Moseev, P.; Selivanenko, O.; Veresnikova, A.; Yanovich, E.; Barros, N.; Baudis, L.; Benato, G.; Kish, A.; Miloradovic, M.; Mingazheva, R.; Walter, M.; Bauer, C.; Hakenmueller, J.; Heisel, M.; Heusser, G.; Hofmann, W.; Kihm, T.; Kirsch, A.; Knoepfle, K.T.; Lindner, M.; Maneschg, W.; Salathe, M.; Schreiner, J.; Schwingenheuer, B.; Simgen, H.; Smolnikov, A.; Stepaniuk, M.; Wagner, V.; Wegmann, A.; Bellotti, E.; Belogurov, S.; Kornoukhov, V.N.; Bettini, A.; Brugnera, R.; Garfagnini, A.; Medinaceli, E.; Sada, C.; Sturm, K. von; Bode, T.; Csathy, J.J.; Lazzaro, A.; Schoenert, S.; Wiesinger, C.; Borowicz, D.; Brudanin, V.; Egorov, V.; Kochetov, O.; Nemchenok, I.; Rumyantseva, N.; Zhitnikov, I.; Zinatulina, D.; Caldwell, A.; Gooch, C.; Kneissl, R.; Liao, H.Y.; Majorovits, B.; Palioselitis, D.; Schulz, O.; Vanhoefer, L.; Cattadori, C.; Salamida, F.; Chernogorov, A.; Demidova, E.V.; Kirpichnikov, I.V.; Vasenko, A.A.; Falkenstein, R.; Freund, K.; Grabmayr, P.; Hegai, A.; Jochum, J.; Schmitt, C.; Schuetz, A.K.; Frodyma, N.; Misiaszek, M.; Panas, K.; Pelczar, K.; Wojcik, M.; Zuzel, G.; Gangapshev, A.; Gusev, K.; Hemmer, S.; Lippi, I.; Stanco, L.; Hult, M.; Lutter, G.; Inzhechik, L.V.; Klimenko, A.; Lubashevskiy, A.; Macolino, C.; Pandola, L.; Pullia, A.; Riboldi, S.; Shirchenko, M.

    2016-01-01

    Neutrinoless double electron capture is a process that, if detected, would give evidence of lepton number violation and the Majorana nature of neutrinos. A search for neutrinoless double electron capture of 36 Ar has been performed with germanium detectors installed in liquid argon using data from Phase I of the GERmanium Detector Array (Gerda) experiment at the Gran Sasso Laboratory of INFN, Italy. No signal was observed and an experimental lower limit on the half-life of the radiative neutrinoless double electron capture of 36 Ar was established: T 1/2 > 3.6 x 10 21 years at 90% CI. (orig.)

  2. Role of the Talaromyces marneffei (Penicillium marneffei) sakA gene in nitrosative stress response, conidiation and red pigment production.

    Science.gov (United States)

    Nimmanee, Panjaphorn; Tam, Emily W T; Woo, Patrick C Y; Vanittanakom, Pramote; Vanittanakom, Nongnuch

    2017-04-01

    Stress-activated MAPK pathways are systems used to regulate the stress adaptation of most fungi. It has been shown that in Talaromyces marneffei (Penicillium marneffei), a pathogenic dimorphic fungus, the sakA gene is involved, not only in tolerance against oxidative and heat stresses, but also in playing a role in asexual development, yeast cell generation in vitro and survival inside macrophage cell lines. In this study, the role of the T. marneffei sakA gene on the nitrosative stress response and the regulation of gene expression were investigated. The susceptibility of the sakA mutant to NaNO2 was investigated using drop dilution assay and the expression of genes of interest were determined by RT-PCR, comparing them to the wild-type and complemented strains. The results demonstrated that the T. marneffei sakA gene played a role in the stress response to NaNO2, the expression of genes functioning in conidial development (brlA, abaA and wetA) and red pigment biosynthesis (pks3, rp1, rp2 and rp3). These findings suggest that T. marneffei sakA is broadly involved in a wide variety of cell activities, including stress response, cell morphogenesis, asexual development and pigmentation. © FEMS 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Investigation of n{sup +} surface events in HPGe detectors for liquid argon background rejection in GERDA

    Energy Technology Data Exchange (ETDEWEB)

    Lehnert, Bjoern [TU-Dresden, Dresden (Germany); Collaboration: GERDA-Collaboration

    2015-07-01

    The GERDA experiment is searching for neutrinoless double beta decay (0νββ) in {sup 76}Ge using an array of germanium detectors immersed in liquid argon (LAr). Phase II of the experiment aims to improve the background level by a factor 10 in order to reach 10{sup -3} counts / (kg.keV.yr). A strong suppression technique is required to suppress the intrinsic LAr background of {sup 42}Ar/{sup 42}K. 30 newly produced p-type Broad Energy Germanium (BEGe) detectors will be deployed in Phase II. The n{sup +} electrode of the GERDA BEGe detectors is covering 96-98 % of the surface and is between 0.5 and 1.2 mm thick. Betas from the {sup 42}K decay can penetrated the detector surface and deposit energies within the 0νββ region. Experiences from GERDA Phase I show that these surface events are the dominate background component without suppression. Energy depositions inside the n{sup +} layer create pulse shapes that are slower than those from interactions in the bulk. This talk presents a rejection technique for those events. The signal development inside the n{sup +} layer is modeled and applied in Geant4 Monte Carlo simulations. The simulations are compared with data for {sup 241}Am and {sup 90}Sr calibration source measurements. The suppression capabilities are extrapolated for {sup 42}K in GERDA Phase II.

  4. Signal and background studies for the search of neutrinoless double beta decay in GERDA

    Energy Technology Data Exchange (ETDEWEB)

    Agostini, Matteo

    2013-04-24

    The GERDA experiment searches for the neutrinoless double beta decay in Ge-76, by operating bare HPGe detectors in ultra-pure liquid Ar. This dissertation presents a first decomposition of the background measured in the current data-taking phase. The background at the energy of interest was found to be dominated by {sup 214}Bi, {sup 208}Tl and {sup 42}K gamma-rays, with secondary contributions from {sup 42}K and {sup 214}Bi beta-rays, and {sup 210}Po alpha-rays. For the forthcoming upgrade of the apparatus, a new HPGe detector design (BEGe) has been studied, with focus on its capability of suppressing the identified backgrounds through pulse shape analysis. This included the development of a comprehensive modeling of the detectors and the experimental characterization of their response to surface interactions. The achieved results show that GERDA can improve the present limit on the neutrinoless double beta decay half-life by an order of magnitude.

  5. Background-free search for neutrinoless double-β decay of76Ge with GERDA.

    Science.gov (United States)

    2017-04-05

    Many extensions of the Standard Model of particle physics explain the dominance of matter over antimatter in our Universe by neutrinos being their own antiparticles. This would imply the existence of neutrinoless double-β decay, which is an extremely rare lepton-number-violating radioactive decay process whose detection requires the utmost background suppression. Among the programmes that aim to detect this decay, the GERDA Collaboration is searching for neutrinoless double-β decay of 76 Ge by operating bare detectors, made of germanium with an enriched 76 Ge fraction, in liquid argon. After having completed Phase I of data taking, we have recently launched Phase II. Here we report that in GERDA Phase II we have achieved a background level of approximately 10 -3 counts keV -1 kg -1 yr -1 . This implies that the experiment is background-free, even when increasing the exposure up to design level. This is achieved by use of an active veto system, superior germanium detector energy resolution and improved background recognition of our new detectors. No signal of neutrinoless double-β decay was found when Phase I and Phase II data were combined, and we deduce a lower-limit half-life of 5.3 × 10 25 years at the 90 per cent confidence level. Our half-life sensitivity of 4.0 × 10 25 years is competitive with the best experiments that use a substantially larger isotope mass. The potential of an essentially background-free search for neutrinoless double-β decay will facilitate a larger germanium experiment with sensitivity levels that will bring us closer to clarifying whether neutrinos are their own antiparticles.

  6. SmSak, the second Polo-like kinase of the helminth parasite Schistosoma mansoni: conserved and unexpected roles in meiosis.

    Directory of Open Access Journals (Sweden)

    Thavy Long

    Full Text Available Polo-like kinases (Plks are a family of conserved regulators of a variety of events throughout the cell cycle, expanded from one Plk in yeast to five Plks in mammals (Plk1-5. Plk1 is the best characterized member of the Plk family, homolog to the founding member Polo of Drosophila, and plays a major role in cell cycle progression by triggering G2/M transition. Plk4/Sak (for Snk (Serum-inducible kinase akin kinase is a unique member of the family, structurally distinct from other Plk members, with essential functions in centriole duplication. The genome of the trematode parasite Schistosoma mansoni contains only two Plk genes encoding SmPlk1 and SmSak. SmPlk1 has been shown already to be required for gametogenesis and parasite reproduction. In this work, in situ hybridization indicated that the structurally conserved Plk4 protein, SmSak, was largely expressed in schistosome female ovary and vitellarium. Expression of SmSak in Xenopus oocytes confirmed its Plk4 conserved function in centriole amplification. Moreover, analysis of the function of SmSak in meiosis progression of G2-blocked Xenopus oocytes indicated that, in contrast to SmPlk1, SmSak cannot induce G2/M transition in the absence of endogenous Plk1 (Plx1. Unexpectedly, meiosis progression was spontaneously observed in Plx1-depleted oocytes co-expressing SmSak and SmPlk1. Molecular interaction between SmSak and SmPlk1 was confirmed by co-immunoprecipitation of both proteins. These data indicate that Plk1 and Plk4 proteins have the potential to interact and cross-activate in cells, thus attributing for the first time a potential role of Plk4 proteins in meiosis/mitosis entry. This unexpected role of SmSak in meiosis could be relevant to further consider the function of this novel Plk in schistosome reproduction.

  7. Penyusunan dan Penyajian Laporan Keuangan Berbasis Sak Etap (Studi pada UMKM Ekspedisi CV. Mandiri) Periode Tahun 2014 Farah Lydia Eka Rini

    OpenAIRE

    B41111036, Farah Lydia Eka Rini B41111036 Farah

    2015-01-01

    Standar Akuntansi Keuangan Entitas Tanpa Akuntabilitas Publik (SAK ETAP) merupakan standar keuangan yang ditetapkan untuk mempermudah UMKM dalam menyusun dan menyajikan laporan keuangan yang lebih informatif dengan tujuan memberikan kemudahan bagi para investor maupun kreditor dalam memberikan bantuan pembiayaan bagi pengusaha UMKM. Penelitian ini dirancang untuk menghasilkan suatu format laporan keuangan sederhana untuk UMKM yang berbasis SAK ETAP. Objek penelitian ini adalah UMKM CV. Mandir...

  8. Teadlased loovad laboris narkokoera tehisnina / Vilja Kohler

    Index Scriptorium Estoniae

    Kohler, Vilja, 1966-

    2004-01-01

    Bionina projekti kallal on 2000. aastast töötanud Tartu Ülikooli kolloid- ja keskkonnakeemia õppetooli teadur filosoofiadoktor Toonika Rinken, Tartu Ülikooli orgaanilise ja bioorgaanilise keemia instituudi teadlased professor Ago Rinken ja teadur Gerda Raidaru. Samas ka: Maailma levinuim biosensor aitab suhkruhaigeid. Lisa: Biosensor kopeerib meeleelundeid

  9. The slow control system of the GERDA double beta decay experiment at Gran Sasso

    International Nuclear Information System (INIS)

    Brugnera, R; Garfagnini, A; Gigante, G; Hemmer, S; Zinato, D; Costa, F; Lippi, I; Michelotto, M; Ur, C

    2012-01-01

    GERDA is an experiment designed and built to study double beta decays of 76 Ge. It is currently in operation at the Gran Sasso underground laboratories (LNGS). A custom slow control system has been designed to monitor and control all the critical parameters for the proper functioning of the experiment. The main sub-components of the experiment (Cryostat, Clean Room, Water Tank, electronic crates and temperatures, High Voltage Systems, Radon Monitor and Source Insertion System) are constantly monitored by several distributed clients which write acquired data to a relational database (PostgreSQL). The latter allows to maintain a history of the whole experiment and, performing correlation between different and independent components, is useful to debug possible system malfunctions. The system is complemented by a Web server, a lightweight and efficient interface to the user on shifts and to the on-call experts, and by a dedicated Alarm dispatcher which distributes the errors generated by the components to the users allowing to react in short time. The whole project has been built around open source and custom software.

  10. SOLVENT-BASED ENHANCED OIL RECOVERY PROCESSES TO DEVELOP WEST SAK ALASKA NORTH SLOPE HEAVY OIL RESOURCES

    Energy Technology Data Exchange (ETDEWEB)

    David O. Ogbe; Tao Zhu

    2004-01-01

    A one-year research program is conducted to evaluate the feasibility of applying solvent-based enhanced oil recovery processes to develop West Sak and Ugnu heavy oil resources found on the Alaska North Slope (ANS). The project objective is to conduct research to develop technology to produce and market the 300-3000 cp oil in the West Sak and Ugnu sands. During the first phase of the research, background information was collected, and experimental and numerical studies of vapor extraction process (VAPEX) in West Sak and Ugnu are conducted. The experimental study is designed to foster understanding of the processes governing vapor chamber formation and growth, and to optimize oil recovery. A specially designed core-holder and a computed tomography (CT) scanner was used to measure the in-situ distribution of phases. Numerical simulation study of VAPEX was initiated during the first year. The numerical work completed during this period includes setting up a numerical model and using the analog data to simulate lab experiments of the VAPEX process. The goal was to understand the mechanisms governing the VAPEX process. Additional work is recommended to expand the VAPEX numerical study using actual field data obtained from Alaska North Slope.

  11. Performance and stability tests of bare high purity germanium detectors in liquid argon for the GERDA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Barnabe Heider, Marik

    2009-05-27

    GERDA will search for neutrinoless double beta decay of {sup 76}Ge by using a novel approach of bare germanium detectors in liquid argon (LAr). Enriched germanium detectors from the previous Heidelberg-Moscow and IGEX experiments have been reprocessed and will be deployed in GERDA Phase-I. At the center of this thesis project is the study of the performance of bare germanium detectors in cryogenic liquids. Identical detector performance as in vacuum cryostats (2.2 keV FWHM at 1.3 MeV) was achieved in cryogenic liquids with a new low-mass detector assembly and contacts. One major result is the discovery of a radiation induced leakage current (LC) increase when operating bare detectors with standard passivation layers in LAr. Charge collection and build-up on the passivation layer were identified as the origin of the LC increase. It was found that diodes without passivation do not exhibit this feature. Three month-long stable operation in LAr at {proportional_to} 5 pA LC under periodic gamma irradiation demonstrated the suitability of the modi ed detector design. Based on these results, all Phase-I detectors were reprocessed without passivation layer and subsequently successfully characterized in LAr in the GERDA underground Detector Laboratory. The mass loss during the reprocessing was {proportional_to}300 g out of 17.9 kg and the exposure above ground {proportional_to} 5 days. This results in a negligible cosmogenic background increase of {proportional_to} 5.10{sup -4} cts/(keV.kg.y) at {sup 76}Ge Q{sub {beta}}{sub {beta}} for {sup 60}Co and {sup 68}Ge. (orig.)

  12. Water physics and chemistry data from bottle casts from the GERDA as part of the Rosenstiel School of Marine and Atmospheric Science (RSMAS) project from 20 July 1955 to 29 May 1957 (NODC Accession 7000057)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Water physics and chemistry data were collected from bottle casts from the GERDA from 20 July 1955 to 29 May 1957. Data were collected as part of the Rosenstiel...

  13. Results on ββ decay with emission of two neutrinos or Majorons in 76Ge from GERDA Phase I

    International Nuclear Information System (INIS)

    Agostini, M.; Bode, T.; Budjas, D.; Csathy, J.J.; Lazzaro, A.; Schoenert, S.; Allardt, M.; Domula, A.; Lehnert, B.; Schneider, B.; Wester, T.; Wilsenach, H.; Zuber, K.; Bakalyarov, A.M.; Belyaev, S.T.; Lebedev, V.I.; Zhukov, S.V.; Balata, M.; D'Andrea, V.; Di Vacri, A.; Junker, M.; Laubenstein, M.; Macolino, C.; Zavarise, P.; Barabanov, I.; Bezrukov, L.; Doroshkevich, E.; Fedorova, O.; Gurentsov, V.; Kazalov, V.; Kuzminov, V.V.; Lubsandorzhiev, B.; Moseev, P.; Selivanenko, O.; Veresnikova, A.; Yanovich, E.; Barros, N.; Baudis, L.; Benato, G.; Walter, M.; Bauer, C.; Heisel, M.; Heusser, G.; Hofmann, W.; Kihm, T.; Kirsch, A.; Knoepfle, K.T.; Lindner, M.; Maneschg, W.; Salathe, M.; Schreiner, J.; Schwingenheuer, B.; Simgen, H.; Smolnikov, A.; Stepaniuk, M.; Wagner, V.; Wegmann, A.; Becerici-Schmidt, N.; Caldwell, A.; Liao, H.Y.; Majorovits, B.; Palioselitis, D.; Schulz, O.; Vanhoefer, L.; Bellotti, E.; Belogurov, S.; Kornoukhov, V.N.; Bettini, A.; Brugnera, R.; Garfagnini, A.; Hemmer, S.; Medinaceli, E.; Sada, C.; Sturm, K. von; Borowicz, D.; Brudanin, V.; Egorov, V.; Kochetov, O.; Nemchenok, I.; Rumyantseva, N.; Zhitnikov, I.; Zinatulina, D.; Cattadori, C.; Chernogorov, A.; Demidova, E.V.; Kirpichnikov, I.V.; Vasenko, A.A.; Falkenstein, R.; Freund, K.; Grabmayr, P.; Hegai, A.; Jochum, J.; Schmitt, C.; Schuetz, A.K.; Frodyma, N.; Misiaszek, M.; Panas, K.; Pelczar, K.; Wojcik, M.; Zuzel, G.; Gangapshev, A.; Gusev, K.; Hult, M.; Lutter, G.; Inzhechik, L.V.; Klimenko, A.; Lippi, I.; Stanco, L.; Ur, C.A.; Lubashevskiy, A.; Pandola, L.; Pullia, A.; Riboldi, S.; Shirchenko, M.

    2015-01-01

    A search for neutrinoless ββ decay processes accompanied with Majoron emission has been performed using data collected during Phase I of the GERmanium Detector Array (GERDA) experiment at the Laboratori Nazionali del Gran Sasso of INFN (Italy). Processes with spectral indices n = 1, 2, 3, 7 were searched for. No signals were found and lower limits of the order of 10 23 yr on their half-lives were derived, yielding substantially improved results compared to previous experiments with 76 Ge. A new result for the half-life of the neutrino-accompanied ββ decay of 76 Ge with significantly reduced uncertainties is also given, resulting in T 1/2 2ν = (1.926 ± 0.094) @ x 10 21 yr. (orig.)

  14. Search for 2νββ excited state transitions and HPGe characterization for surface events in GERDA phase II

    Energy Technology Data Exchange (ETDEWEB)

    Lehnert, Bjoern

    2016-03-01

    The search for the neutrinoless double beta (0νββ) decay is one of the most active fields in modern particle physics. This process is not allowed within the Standard Model and its observation would imply lepton number violation and would lead to the Majorana nature of neutrinos. The experimentally observed quantity is the half-life of the decay, which can be connected to the effective Majorana neutrino mass via nuclear matrix elements. The latter can only be determined theoretically and are currently affected by large uncertainties. To reduce these uncertainties one can investigate the well established two-neutrino double beta (2νββ) decay into the ground and excited states of the daughter isotope. These similar processes are allowed within the Standard Model. In this dissertation, the search for 2νββ decays into excited states is performed in {sup 110}Pd, {sup 102}Pd and {sup 76}Ge. Three gamma spectroscopy setups at the Felsenkeller (Germany), HADES (Belgium) and LNGS (Italy) underground laboratories are used to search for the transitions in {sup 110}Pd and {sup 102}Pd. No signal is observed leading to lower half-live bounds (90% C.I.) of 2.9 . 10{sup 20} yr, 3.9 . 10{sup 20} yr and 2.9 . 10{sup 20} yr for the 0/2νββ 2{sup +}{sub 1}, 0{sup +}{sub 1} and 2{sup +}{sub 2} transitions in {sup 110}Pd and 7.9 . 10{sup 18} yr, 9.2 . 10{sup 18} yr and 1.5 . 10{sup 19} yr for the 0/2νββ 2{sup +}{sub 1}, 0{sup +}{sub 1} and 2{sup +}{sub 2} transitions in {sup 102}Pd, respectively. This is a factor of 1.3 to 3 improvement compared to previous limits. The data of Phase I (Nov 2011 - May 2013) of the 0νββ decay experiment GERDA at LNGS is used to search for excited state transitions in {sup 76}Ge. The analysis is based on coincidences between two detectors and finds no signal. Lower half-life limits (90 % C.L.) of 1.6.10{sup 23} yr, 3.7.10{sup 23} yr and 2.3.10{sup 23} yr are obtained for the 2νββ 2{sup +}{sub 1}, 0{sup +}{sub 1} and 2{sup +}{sub 2

  15. Quadruple or quintuple conversion of hlb, sak, sea (or sep), scn, and chp genes by bacteriophages in non-beta-hemolysin-producing bovine isolates of Staphylococcus aureus.

    Science.gov (United States)

    Kumagai, Rina; Nakatani, Kazue; Ikeya, Nanami; Kito, Yukiko; Kaidoh, Toshio; Takeuchi, Shotaro

    2007-05-16

    In 13 of 43 non-beta-hemolysin-producing bovine isolates of Staphylococcus aureus, two truncated beta-hemolysin (hlb) genes were demonstrated by PCR and sequencing, and one truncated hlb gene was located beside the integrase (int) gene of phage origin. The staphylokinase (sak) gene was detected in all 13 isolates in which the truncated hlb genes were detected by PCR. Enterotoxin A (sea) and enterotoxin P (sep) genes were also detected in 5 and 2 of the 13 isolates, respectively. Moreover, the scn and chp genes encoding staphylococcal complement inhibitor (SCIN) and chemotaxis inhibitory protein of S. aureus (CHIPS) were detected in 13 and 4 of the 13 isolates, respectively. The bacteriophage induced by mitomycin C treatment was able to lysogenize one beta-hemolysin-producing isolate of S. aureus, and the sak and scn genes were detected from the lysogenized isolate. These results suggest quadruple or quintuple conversion of hlb, sak, sea (or sep), scn, and chp genes by bacteriophages among non-beta-hemolysin-producing bovine isolates of S. aureus.

  16. Search for the neutrinoless double β-decay in GERDA phase I using a pulse shape discrimination technique

    Energy Technology Data Exchange (ETDEWEB)

    Kirsch, Andrea

    2014-07-09

    The Germanium Detector Array (Gerda) experiment, located underground at the INFN Laboratori Nazionali del Gran Sasso (LNGS) in Italy, deploys high-purity germanium detectors to search for the neutrinoless double β-decay (0νββ) of {sup 76}Ge. An observation of this lepton number violating process, which is expected by many extensions of the Standard Model, would not only generate a fundamental shift in our understanding of particle physics, but also unambiguously prove the neutrino to have a non-vanishing Majorana mass component. A first phase of data recording lasted from November 2011 to May 2013 - resulting in a total exposure (defined as the product of detector mass and measurement time) of 21.6 kg.yr. Within this thesis a thorough study of this data with special emphasis on the development and scrutiny of an active background suppression technique by means of a signal shape analysis has been performed. Among several investigated multivariate approaches, particularly a selection algorithm based on an artificial neural network is found to yield the best performance; i.a. the background index close to the Q-value of the 0νββ-decay could be suppressed by 45% to 1.10{sup -2} cts/(keV.kg.yr), while still retaining a considerably high signal survival fraction of (83±3)% leading to a significant improvement of the experimental sensitivity. The efficiency is derived by a simulation and further validated by substantiated consistency checks availing themselves of measurements taken with different calibration sources and physics data. No signal is observed and a new lower limit of T{sup 0ν}{sub 1/2} (90%C.L.)> 2.2. 10{sup 25} yr for the half-life of neutrinoless double β-decay of {sup 76}Ge is established.

  17. Pulse shape analysis for the GERDA experiment to set a new limit on the half-life of 0νββ decay of {sup 76}Ge

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, Victoria Elisabeth

    2017-01-25

    The GERDA experiment searches for neutrinoless double beta (0νββ) decay of {sup 76}Ge using high purity germanium (HPGe) detectors operated in liquid argon (LAr). The aim is to explore half-lives of the order of 10{sup 26} yr. Therefore, GERDA relies on improved active background reduction techniques such as pulse shape discrimination (PSD) in which the time structure of the germanium signals is analyzed to discriminate signal- from background-like events. Two types of HPGe detectors are operated: semi-coaxial detectors previously used in the Heidelberg-Moscow and IGEX experiments and new Broad Energy Germanium (BEGe) detectors which feature an improved energy resolution and enhanced PSD. In Phase I of the experiment, five enriched BEGe detectors were used for the first time in the search for 0νββ decay. A PSD based on a single parameter, the ratio of the maximum current amplitude over the energy A/E is applied. 83% of the background events in a 232 keV region around Q{sub ββ} are rejected with a high signal efficiency of (92.1 ± 1.9) %. The achieved background index (BI) is (5.4{sup +4.1}{sub -3.4}) . 10{sup -3} (counts)/(keV.kg.yr). This is an improvement by a factor of 10 compared to previous germanium based 0νββ experiments. Phase II of the experiment includes a major upgrade: for further background rejection, the LAr cryostat is instrumented to detect argon scintillation light. Additional 25 BEGe detectors are installed. After PSD and LAr veto a BI of (0.7{sup +1.3}{sub -0.5}) . 10{sup -3} (counts)/(keV.kg.yr) is achieved. This is the best BI achieved in 0νββ experiments so far. A frequentist statistical analysis is performed on the combined data collected in GERDA Phase I and the first Phase II release. A new limit on the half-life of 0νββ decay of {sup 76}Ge is set to T{sup 0ν}{sub 1/2}>5.3.10{sup 25} yr at 90% C.L., with a median sensitivity of T{sup 0ν}{sub 1/2}>4.0.10{sup 25} yr at 90% C.L.

  18. Risk analysis and reliability of the GERDA Experiment extraction and ventilation plant at Gran Sasso mountain underground laboratory of Italian National Institute for Nuclear Physics

    Energy Technology Data Exchange (ETDEWEB)

    Lombardi, Mara; Garzia, Fabio; Guarascio, Massimo; Giovannone, Enzo Paolo; Giampaoli, Antonio; Musti, Mafalda; Ranalli, Maria Teresa; Perruzza, Roberto; Tartaglia, Roberto, E-mail: mara.lombardi@uniroma1.it, E-mail: fabio.garzia@uniroma1.it, E-mail: massimo.guarascio@uniroma1.it [Universita degli Studi di Roma La Sapienza-Engineering Roma (Italy); Corpo Nazionale Vigili del Fuoco L' Aquila (CNVF) (Italy); Istituto Nazionale di Fisica Nucleare - Laboratori del Gran Sasso L' Aquila, Abruzzo (Italy)

    2017-07-15

    The aim of this study is the risk analysis evaluation about argon release from the GERDA experiment in the Gran Sasso underground National Laboratories (LNGS) of the Italian National Institute for Nuclear Physics (INFN). The GERDA apparatus, located in Hall A of the LNGS, is a facility with germanium detectors located in a wide tank filled with about 70 m{sup 3} of cold liquefied argon. This cryo-tank sits in another water-filled tank (700 m{sup 3} ) at atmospheric pressure. In such cryogenic processes, the main cause of an accidental scenario is lacking insulation of the cryo-tank. A preliminary HazOp analysis has been carried out on the whole system. The risk assessment identified two possible top-events: explosion due to a Rapid Phase Transition - RPT and argon runaway evaporation. Risk analysis highlighted a higher probability of occurrence of the latter top event. To avoid emission in Hall A, the HazOp, Fault Tree and Event tree analyses of the cryogenic gas extraction and ventilation plant have been made. The failures related to the ventilation system are the main cause responsible for the occurrence. To improve the system reliability some corrective actions were proposed: the use of UPS and the upgrade of damper opening devices. Furthermore, the Human Reliability Analysis identified some operating and management improvements: action procedure optimization, alert warnings and staff training. The proposed model integrates the existing analysis techniques by applying the results to an atypical work environment and there are useful suggestions for improving the system reliability. (author)

  19. Vanemapalk õiglasemaks! / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2005-01-01

    Ilmunud ka Vali Uudised 9. märts lk. 2, Põhjarannik 9. märts lk. 2, Severnoje Poberezhje 9. märts lk. 2, Pärnu Postimees 9. märts lk. 2, Sakala 9. märts lk. 2, Vooremaa 10. märts lk. 2, Hiiu Leht 11. märts lk. 2, Virumaa Teataja 17. märts lk. 7. Autor toob ära sotsiaaldemokraatide poolt väljapakutavad vanemapalga põhimõttelised muudatused

  20. [Gerda Alexander eutonia].

    Science.gov (United States)

    Murcia, R

    1991-01-01

    One of the most important objectives of euronia is to find the adequate tonus in situations of total rest or of maximum dynamism. The dimension of tonic mastery together with relaxation make eutonia an extremely useful method in phoniatrics and orthophony.

  1. Characterization of the liquid argon veto of the GERDA experiment and its application for the measurement of the {sup 76}Ge half-life

    Energy Technology Data Exchange (ETDEWEB)

    Wegmann, Anne Christin

    2017-01-18

    The search for neutrinoless double-beta decay (0νββ) is one of the most active fields in modern particle physics as the observation of this process would prove lepton number violation and imply new physics beyond the Standard Model of particle physics. The GERDA experiment searches for this decay by operating bare Germanium detectors, enriched in the ββ isotope {sup 76}Ge, in liquid argon. For the first time, a ββ-experiment combines the excellent properties of semiconductor Germanium detectors with an active background suppression technique based on the simultaneous detection of liquid argon scintillation light by photomultiplier tubes and silicon photomultipliers coupled to scintillating fibers (LAr veto). The LAr veto has been successfully operated during the first six months of Phase II of the experiment and yielded - in combination with a Germanium detector pulse shape discrimination technique - a background index of (0.7{sup +1.1}{sub -0.5}).10{sup -3} ((cts)/(kg.keV.yr)). With an ultimate exposure of 100 kg.yr this will allow for a 0νββ-decay half-life sensitivity of the Gerda Phase II experiment of 10{sup 26} yr. Double-beta decay under the emission of two neutrinos (2νββ) is a second-order process but which is allowed by the Standard Model. The excellent background reduction of the LAr veto results in an unprecedented signal-to-background ratio of 30:1 in the energy region dominated by 2νββ-decay of {sup 76}Ge. The remaining background after LAr veto is estimated using the suppression factor from calibration source measurements and results in a measurement of T{sup 2ν}{sub 1/2}=(1.98±0.02(stat)±0.05(syst)).10{sup 21} yr and T{sub 1/2}{sup 2ν}=(1.92 ±0.02(stat)±0.11(syst)).10{sup 21} yr based on two different detector designs and give uncertainties on the detector parameters but both with improved systematic uncertainties in comparison to earlier measurements.

  2. Liquid argon as active shielding and coolant for bare germanium detectors. A novel background suppression method for the GERDA 0{nu}{beta}{beta} experiment

    Energy Technology Data Exchange (ETDEWEB)

    Peiffer, J.P.

    2007-07-25

    Two of the most important open questions in particle physics are whether neutrinos are their own anti-particles (Majorana particles) as required by most extensions of the StandardModel and the absolute values of the neutrino masses. The neutrinoless double beta (0{nu}{beta}{beta}) decay, which can be investigated using {sup 76}Ge (a double beta isotope), is the most sensitive probe for these properties. There is a claim for an evidence for the 0{nu}{beta}{beta} decay in the Heidelberg-Moscow (HdM) {sup 76}Ge experiment by a part of the HdM collaboration. The new {sup 76}Ge experiment Gerda aims to check this claim within one year with 15 kg.y of statistics in Phase I at a background level of {<=}10{sup -2} events/(kg.keV.y) and to go to higher sensitivity with 100 kg.y of statistics in Phase II at a background level of {<=}10{sup -3} events/(kg.keV.y). In Gerda bare germanium semiconductor detectors (enriched in {sup 76}Ge) will be operated in liquid argon (LAr). LAr serves as cryogenic coolant and as high purity shielding against external background. To reach the background level for Phase II, new methods are required to suppress the cosmogenic background of the diodes. The background from cosmogenically produced {sup 60}Co is expected to be {proportional_to}2.5.10{sup -3} events/(kg.keV.y). LAr scintillates in UV ({lambda}=128 nm) and a novel concept is to use this scintillation light as anti-coincidence signal for background suppression. In this work the efficiency of such a LAr scintillation veto was investigated for the first time. In a setup with 19 kg active LAr mass a suppression of a factor 3 has been achieved for {sup 60}Co and a factor 17 for {sup 232}Th around Q{sub {beta}}{sub {beta}} = 2039 keV. This suppression will further increase for a one ton active volume (factor O(100) for {sup 232}Th and {sup 60}Co). LAr scintillation can also be used as a powerful tool for background diagnostics. For this purpose a new, very stable and robust wavelength

  3. Necip Fazıl Kısakürek’in Yunus Emre Adlı Tiyatro Eseri Üzerine Bir İnceleme A Study About Yunus Emre, A Theatre Work Written By Necip Fazıl Kısakürek

    Directory of Open Access Journals (Sweden)

    Turan GÜLER

    2012-09-01

    Full Text Available Yunus Emre who lived between the XII- XIV centuries is one of the prominent figures of Islamic thought history. The effect of him has endured in different fields until today, and now he is handled in a play (theatre work ya da presentation. Necip Fazıl Kısakürek who attaches great importance to theatre in all literary genre in his play, Yunus Emre, appointed Yunus Emre as the protagonist of the play. In this work, Necip Fazıl Kısakürek's play “Yunus Emre” is going to be analyzed in respect to its structural components such as identity analysis, subject, plot, personality analysis, and place and scene analysis. The tale- based life of Yunus Emre who has a prominent place in Turkish-Islamic history is pictured in this monument. In this table, on one hand Yunus Emre's adventure beginning with his coming to Anatolia is told, and on the other hand his mystical travel that he experienced by means of his poems is narrated. In the play, references are made to some social and political events that took place at time of Yunus Emre in Anatolia. Issues such as Mongol attacks and Mongol domination in Anatolia, the last situation of State of the Seljuks, the conflicts among the Principalities, the despair of the public, the various roles that the sects undertook during that chaos also take place in that play. In our survey, beside the structural elements, also such kind of thematic cases are mentioned. In this way, the sophisticated identity of Yunus Emre is aimed to be manifested. Ultimately, an important matter for yunus Emre, „Great Jihad‟ that is to say self-discipline, which is also the main subject of the thesis is pointed out. Yunus Emre, XIII.-XIV. Yüzyıllarda yaşayan, Türk – İslam düşünce tarihinin önemli isimlerinden biridir. Şiirleri aracılığı ile yayılma imkânı bulan düşüncelerinin etkisi günümüze kadar farklı alanlarda sürmüş olan Yunus Emre, bu defa bir tiyatro oyunu içinde ele alınmıştır. Edebi t

  4. Populaarsemad raamatud : [Sõnum] / Ita Saks

    Index Scriptorium Estoniae

    Saks, Ita, 1921-2003

    1996-01-01

    Aasta populaarseimad raamatud läti kirjanduses: Vizma Belshevica 'Bille', Regina Ezera 'Lohe Muna' ja Karlis Levinshi 'Muinasjutujärve ääres'; populaarseimad publitsistikaraamatud on Guntis Ulmanise 'Sinult ju palju ei nõuta' ja Dainis Ivansi 'Juhuslik sõdalane'

  5. Venemaal sotsiaaldemokraatiat otsimas / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Euroopa Sotsiaaldemokraatliku Partei (ESP) ja Alfred Moseri fondi koostöös toimunud visiidist Venemaale, kus osalesid mitme Lääne sotsiaaldemokraatliku partei esindajad, kohtumisest endise Jabloko esimehe Grigori Javlinski, Venemaa Sotsiaaldemokraatliku Partei looja Mihhail Gorbatshovi ja selle praeguse esimehe Vladimir Kishenini ning partei Õiglane Venemaa juhi Sergei Mironoviga

  6. Positive effects, side effects, and adverse events of clinical holistic medicine. A review of Gerda Boyesen's nonpharmaceutical mind-body medicine (biodynamic body-psychotherapy) at two centers in the United Kingdom and Germany.

    Science.gov (United States)

    Allmer, Charlotte; Ventegodt, Søren; Kandel, Isack; Merrick, Joav

    2009-01-01

    To review adverse events of intensive, clinical holistic medicine (CHM) as it is practiced in holistic body-psychotherapy in England and Germany. Gerda Boyesen's "biodynamic body-psychotherapy" (BBP) is an intensive type of holistic mind-body medicine used by Boyesen at two centers. About 13,500 patients were treated during 1985-2005 period and studied for side effects and adverse events. The first author worked closely with Boyesen 1995-2005 with full insight in all aspects of the therapy and provided the data on side-effects. Therapy helped chronic patients with physical, psychological, sexual, psychiatric and existential problems to improve health, ability, and quality of life (NNT (number needed to treat) = 1-3). Effective in the treatment of mentally ill patients (schizophrenia, anxiety, poor mental health, low general ability). For retraumatization, brief reactive psychosis, depression, depersonalization and derealization, implanted memories, side effects from manipulations of the body, suicide/suicide attempts, hospitalization for physical and mental health problem during or 90 days after treatment, NNH (number needed to harm) > 13,500. Intensive, holistic non-drug medicine is helpful for physical, sexual, psychological, psychiatric and existential problems and is completely safe for the patient. The therapeutic value TV = NNH/NNT > 5,000. Altogether about 18,000 patients treated with different subtypes of CHM in four different countries have now been evaluated for effects, side effects and adverse events, with similar results.

  7. Schröderiseeruv Euroopa / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Euroopa Parlamendi saadik on seisukohal, et Euroopa Liidus hakkab saama igapäevaseks, et poliitikute ind kellelegi meeldida ületab soovi töötada Euroopa üksmeele nimel. Eriti valusalt torkab silma soov meeldida Venemaale

  8. Harmonisasi SAK dan Aturan Pajak: Mungkinkah?

    Directory of Open Access Journals (Sweden)

    Heri Sukendar Sukendar

    2014-11-01

    Full Text Available This paper is intended to illustrate the fact that the case today, especially in Indonesia's commitment to convergency of IFRS, where the decision was certainly not out of global importance that in order to improve the information from the financial statements of companies in Indonesia. In addition, the IFRS Convergence is one of the Indonesian government agreements as a member of the G20 forum, the results of the meeting of G20 leaders in Washington DC forum, 15 November 2008. On the other hand, the tax rules that apply are still using the old accounting standards and do not follow the development of increasingly different. Previous differences between GAAP and tax rules are limited to the "deductible and non-deductible" which is resolved through fiscal reconciliation mechanism with positive correction and correction negatipnya. The widening gap today would be a separate issue for IAI as the organization of the accounting profession. Tax Accountant compartment formation in March 2014 is a serious evidence of the organization as an anticipation, particularly in an effort to bridge the gap widening

  9. Jutud / Jerome K Jerome ; tlk. Gerda Kroom

    Index Scriptorium Estoniae

    Jerome, Jerome K., 1859-1927

    1997-01-01

    Järjejutt. Lõpp: 26. juuni 1997. Sisu : Onu Podger töötamas; Joostes rongile; Kaks tüdrukut sisseoste tegemas; Tandem; Mees, kes ei uskunud õnne; Hajameelne mees; Telefoni esimesed sammud; Üks hea nõuanne; Vestlussõnastikud; Kas parandada või sõita?

  10. KUALITAS LAPORAN KEUANGAN UMKM SERTA PROSPEK IMPLEMENTASI SAK ETAP

    Directory of Open Access Journals (Sweden)

    Rizki Rudiantoro

    2012-06-01

    Full Text Available This study examines the effect of quality of the SMEs’ financial statements on level of credit received by SMEs, as well as prospect of financial accounting standard for entity without public accountability (FAS EWPA implementation in 2011 to improve the quality of the financial statements of SMEs. The data of this study is obtained from the questionnaires returned by 50 SME entrepreneurs in the area of Jakarta, Bogor, Depok, and other parts of Java. The results of this study show that the quality of SME financial statements do not affect the amount of credit received by SMEs. This may be due to the low quality of financial statements of SMEs so that banks are still in doubt with the relevancy and reliability of financial reporting. Prospect of FAS EWPA implementation to improve the quality of financial report may have been constrained due to the low understanding of the SME entrepreneurs over the FAS EWPA.

  11. Kas holokaust võib korduda? / Elhonen Saks

    Index Scriptorium Estoniae

    Saks, Elhonen, 1927-

    2000-01-01

    Eestit külastas USA Kongressi Esindajatekoja välissuhete komisjoni liige Tom Lantos. Dokumentaalfilm "Viimased päevad" ("The Last Days") Eesti välisministeeriumi pressikeskuses. režissöör James Moll : Ameerika Ühendriigid 1998. Survivors of the Shoah Visual History Foundation algatus. Filmi esitusel osalesid ka L. Meri ja T. H. Ilves.

  12. Toiduvilja koht pole kütusepaagis / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Ilmunud ka: Nädaline 22. mai, lk. 4, Pärnu Postimees 22. mai, lk. 15, Võrumaa Teataja 22. mai, lk. 2, Vooremaa 22. mai, lk. 2, Valgamaalane 22. mai lk. 2, Hiiu Leht 23. mai, lk. 2, Kuulutaja 23. mai lk. 4, Koit 24. mai lk. 6, Järva Teataja, Harju Elu 27. mai lk. 2, Vali Uudised 28. mai lk. 2, Meie Maa 29. mai lk. 2, Lääne Elu 5. juuni lk. 2, Virumaa Teataja 6. juuni, lk. 11, Sakala 6. juuni lk. 2, Molodjozh Estonii 9. juuni lk. 7. Euroopa Parlamendi liige annab ülevaate EL biokütusepoliitikast

  13. Laste hulk ei sõltu toonekurgede arvukusest / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2006-01-01

    Perekonnaseaduse eelnõust ja samasooliste abielust. Sama ka Harjumaa 24. jaan. 2006, lk. 2 ; Võrumaa Teataja 24. jaan. 2006, lk. 2 ; Vali Uudised 25. jaan. 2006, lk. 2 ; Meie Maa 25. jaan. 2006, lk. 2 ; Hiiu Leht 27. jaan. 2006, lk. 2 ; Kuulutaja 27. jaan. 2006, lk. 4 ; Lõunaleht 26. jaan. 2006, lk. 2 ; Vooremaa 26. jaan. 2006, lk. 2 ; Pärnu Postimees 2. veeb. 2006, lk. 11 ; Sakala 2. veeb. 2006, lk. 2 ; Valgamaalane 25. aprill 2006, lk. 2 ; Hiiu Leht 9. mai 2006, lk. 2 ; Sotsiaaldemokraat 16. veeb. 2006, lk. 5

  14. Äraaetud hobused lastakse maha / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Tööaja direktiivi muutmise eelnõust, mis suurendaks töötajate tööaja piiranguid. Ilmunud ka Põhjarannik 19. juuni 2008, lk.2 ; Vooremaa 21. juuni 2008, lk. 2 ; Virumaa Teataja 27. juuni 2008, lk. 11 ; Pärnu Postimees 27. juuni 2008, lk. 15 ; Järva Teataja 1. juuli 2008, lk. 2 ; Koit 3. juuli 2008, lk. 6 ; Nädalaleht 20. juuni 2008, lk. 7

  15. Pikk tee märkamiseni / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Õpilaste koolisuhetest ning koolivägivallast. Ilmunud ka Vooremaa 9. okt. 2008, lk. 2 ; Võrumaa Teataja 11. okt. 2008, lk. 2 ; Koit 11. okt. 2008, lk. 6 ; Meie Maa 13. okt. 2008, lk. 2 ; Pärnu Postimees 10. okt. 2008, lk. 15 ; Virumaa Teataja 15. okt. 2008, lk. 11

  16. Kirjandus- ja kultuuritegelased Pärnu Alevi kalmistul / Gerda Kuum

    Index Scriptorium Estoniae

    Kuum, Gerda

    2007-01-01

    Jutukirjanik Suve Jaan, kodanikunimega Sommer Johann Friedrich (1777-1851); baltisaksa kirjamees ja pastor Johann Heinrich Rosenplänter (1782-1846); kirjamees ja köster Caspar Franz Lorenzsonn (1811-1880); köster Heinrich Gottlieb Lorenzsonn (1803-1847); trükkal ja kirjastaja Friedrich Wilhelm Bonn (1812-1881); linnapead Oskar Alexander Brackmann (1841-1927) ja Jaan Leesment (1870-1941)

  17. Ebavõrdsus hukutab Eesti arengu / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2004-01-01

    Ilmunud ka: Pärnu Postimees, 22. jaan. 2004, lk. 11; Võrumaa Teataja, 24. jaan. 2004, lk. 2; Meie Maa, 24. jaan. 2004, lk. 2; Hiiu Leht, 27. jaan. 2004, lk. 2; Põhjarannik, 31. jaan. 2004, lk. 2; Severnoje Poberezhje, 31. jaan. 2004, lk. 2; Koit, 3. veebr. 2004, lk. 6; Hiiumaa, 3. veebr. 2004, lk. 2. Autor vaatleb riigi osa ebavõrduse ilmingute likvideerimisel Eestis ja leiab, et ebavõrdsus on meie arengu peamine takistus, mille kõrvaldamine on sotsiaaldemokraatide peamine eesmärk

  18. Kto zashtshitit ot grabitelskogo SMS-kredita? / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Kiirlaenudest ja nendega seonduvatest probleemidest Eestis, seaduseelnõust, mis suurendab SMS-laenu võtnute võimalusi kaitsta oma õigusi laenuandjate ees ning olukorra ohjeldamisest Rootsis ja Soomes

  19. Necip Fazıl Kısakürek’in “Kaldırımlar” Şiiri Üzerine Dil Bilimsel Bir Çözümleme A Linguistic Analysis On Necip Fazıl Kısakurek’s Poem Called As ‘Kaldırımlar’

    Directory of Open Access Journals (Sweden)

    Yusuf TEPELİ

    2013-03-01

    önüyle şiirin başarısında ve kalıcılığında büyük paya sahiptir. Şiir dilden ayrı düşünülemeyeceği için şiir eleştirisi de dilden bağımsız gerçekleştirilemez. Şiirin yansıttığı duyguları, okuyucuya yaşattığı atmosferi birtakım öznel değerlendirmelerle aktarmak yerine tamamen metnin kendi söz varlığına dayanan, bilimsel bir yöntemle açıklamak ihtiyacı bu çalışmanın yapılmasında etkili olmuştur. Bu çalışma için Necip Fazıl Kısakürek’in şiirinin tercih edilmesinde şairin sapmalar ve aktarmalarla özgün imgeler yaratması, ses ögelerinden bolca yararlanması, konuşulan dilin verdiği rahat söyleyişi yakalaması etkili olmuştur. Şair kişinin yoğun iç hesaplaşmalarının, ruh çalkantılarının yansımalarını dış dünyanın gerçekliğiyle aktardığı mistik şiirler kaleme almıştır. “Kaldırımlar” şiiri tüm bu nitelikleri içermesi bakımından bizlere ideal bir dil malzemesi sağlamaktadır.Bu çalışmada, Necip Fazıl Kısakürek’in Kaldırımlar adlı şiiri dilbilimsel bakışla çözümlenmeye çalışılmıştır. Bunun için Doğan Aksan'ın "Şiir Dili ve Türk Şiir Dili" adlı eseri temel alınarak, Aksan’ın değişik şiir örnekleri üzerinde gösterdiği şiir inceleme yöntemi bir Kaldırımlar şiiri üzerinde uygulanmıştır.İki bölümden oluşan çalışmanın ilk bölümünde kısaca sözcük türleri üzerinde durulmuş, ikinci bölümde ise metnin söz varlığını oluşturan sözcüklerin dil bilimsel/ anlam bilimsel/ gösterge bilimsel incelemesi yapılmış, bulgular tablolaştırılarak aktarılmıştır. Metinde geçen sözcükler tür, anlam yönü, ses ögeleri bakımından incelenmiş, bunların duygu değerleri, geçiş sıklıkları ve birbirleriyle ilişkileri tespit edilerek çözümlemeye gidilmiştir.

  20. Aspects of vibrio parahaemolyticus(SAK) in fish preservation by irradiation 1. The presence of vibrio parahaemolyticus(SAK) in coastal areas of Sumatra and Java

    International Nuclear Information System (INIS)

    Suhadi, F.

    1984-01-01

    A study was carried out on the presence of vibrio parahaemolyticus in samples of sediment and seafoods originating from the eastern coast of Sumatra and the north coastal areas of Java. In a total of 2.434 samples of sediment and seafoods, 79 (3,3%) were found to contain vibrio parahaemolyticus. Among the 467 sediment samples, 1.650 fish, 133 shellfish, 123 shrimps, and 61 crab samples, 22 (4.7%), 41 (2.5%), 12 (9.0%), 2 (1,6%) and 2 (3.3%) were positive for vibrio parahaemolyticus, respectively. Based on the sampling areas, the high incidence of vibrio parahaemolyticus was found in samples collected from Riau (5.4%), while the samples from East Java was only about 0.4%. The contamination level of vibrio parahaemolyticus in samples collected from coastal areas of Sumatra and Java is relatively lower compared with the data obtained from some other coastal areas in the United States and Japan. (author)

  1. Aspects of vibrio parahaemolyticus(SAK) in fish preservation by irradiation 2. Radiation sensitivity of vibrio parahaemolyticus(SAK) to gamma rays

    International Nuclear Information System (INIS)

    Suhadi, F.

    1985-01-01

    This experiment was done to determine the effect of suspending medium on radiation sensitivity of vibrio parahaemolyticus strains isolated from marine environment. D 10 value of nine strains tested were found to be around 151-281 Gy in fish homogenate, and 102-210 Gy in saline solution. The reduction of vibrio parahaemolyticus in fish homogenate at doses of 500 and 750 Gy were found to be 1.8-3.3 logs and 2.7-5.0 logs, respectively, while in saline solution the values were found to be 2.4-4.9 logs and 3.6-7.4 logs. Radiation sensitivity of vibrio parahaemolyticus varied between strains and also depended upon the suspending medium. (author)

  2. Onu Miltie mälestuseks ehk Mis seob New Orleansi ja Keilat? / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    16. novembril sai kaks aastat liberaalse majanduse guru Milton Friedmani surmast. Friedmani šokidoktriinist, katastroofikapitalismist ja pimedast usust erakapitali, ajal, mil Keila linnaisad olid otsustanud, et haridust hakkab munitsipaalkooli asemel edendama sihtasutus

  3. Kes kaitseb röövelliku kiirlaenu eest? / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Kiirlaenudest ja nendega seonduvatest probleemidest Eestis, seaduseelnõust, mis suurendab SMS-laenu võtnute võimalusi kaitsta oma õigusi laenuandjate ees ning olukorra ohjeldamisest Rootsis ja Soomes. Ilmunud ka Pärnu Postimees 31. okt. 2008, lk. 11, pealkiri kujul: kaitse röövelliku kiirlaenu vastu ja tarbijakaitsepoliitika ; Lõunaleht 6. nov. 2008, lk. 4, pealkiri kujul: kes kaitseb röövelliku kiirlaenu eest ehk tarbijakaitsepoliitika lakmustest ; Vali Uudised 7. nov. 2008, lk. 2 ; Harju Ekspress 7. nov. 2008, lk. 8, pealkiri kujul: kes kaitseb röövelliku kiirlaenu vastu ehk tarbijakaitsepoliitika lakmustest ; Türi Rahvaleht 14. nov. 2008, lk. 4 ; Virumaa Teataja 14. nov. 2008, lk. 11, pealkiri kujul: kiirlaenud on test tarbijakaitsepoliitikale ; Kuulutaja 14. nov. 2008, lk. 4, pealkiri kujul: kes kaitseb kiirlaenu vastu ; Vooremaa 18. nov. 2008, lk. 2 ; Sõnumitooja 26. nov. 2008, lk. 2 ; Koit : Tarbijaleht 27. nov. 2008, lk. 10

  4. Ohutusnõuded laste mänguasjadele muutuvad senisest karmimaks / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Euroopa Komisjoni avaldatud kauaoodatud mänguasjade ohtuse direktiivi eelnõust, mis reguleerib siin müüdavate mängukannide ohutusnõudeid. Ilmunud ka Meie Maa 23. okt. 2008, lk. 2, pealkiri kujul: nõuded laste mänguasjadele muutuvad karmimaks ; Põhjarannik 23. okt. 2008, lk. 2 ; Järva Teataja 25. okt. 2008, lk. 2, pealkiri kujul: lelude ohutusnõuded karmistuvad ; Kuulutaja 24. okt. 2008, lk. 4 ; Oma Saar 6. nov. 2008, lk. 5 ; Pärnu Postimees 7. nov. 2008, lk. 15 ; Valgamaalane 11. nov. 2008, lk. 2

  5. Uued muutused nõuavad enam selgitustööd / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2008-01-01

    Euroopa Liidu otsustest ja nende tähtsusest ning selgitamise vajadusest. Ilmunud ka Koit 22. jaan. 2008, lk. 6, pealkiri kujul: Muutused nõuavad poliitikutelt järjest enam selgitustööd, Meie Maa 22. jaan. 2008, lk. 2 ; Sakala 24. jaan. 2008, lk. 2 ; Valgamaalane 22. jaan. 2008, lk. 2 ; Virumaa Teataja 25. jaan. 2008, lk. 11 ; Lääne Elu 24. jaan. 2008, lk. 2 ; Pärnu Postimees 5. veeb. 2008, lk. 19

  6. Valitsusliit jätab lasteaiaõpetajad virelema / Katrin Saks

    Index Scriptorium Estoniae

    Saks, Katrin, 1956-

    2004-01-01

    Koolieelsete lasteasutuste seaduse muutmise seaduseelnõu hääletati Riigikogu menetlusest välja, vanemahüvitistest. Ilmunud ka Pärnu Postimees 23. sept. 2004, lk. 15 ; Hiiu Leht 24. sept. 2004, lk. 2 ; Sakala 24. sept. 2004, lk. 2 ; Vali Uudised 24. sept. 2004, lk. 2 ; Nädaline 23. sept. 2004, lk. 4 ; Põhjarannik 24. sept. 2004, lk. 2 ; Türi Rahvaleht 24. sept. 2004, lk. 4, Meie Maa 28. sept. 2004. lk. 2 ; Koit 30. sept. 2004, lk. 6 ; Vooremaa 7. okt. 2004, lk. 2 ; Valgamaalane 16. okt. 2004, lk. 2

  7. OP U WOORD SAL EK DIE NET LAAT SAK".* Gemeente van Jesus ...

    African Journals Online (AJOL)

    Test

    Gemeente van Jesus Christus,. Toe die apostel Paulus, daar op die strand van Milete afskeid geneem het van die ouderlinge van die gemeente van Efese, het hy onder meer ook hierdie woorde uitgespreek, dat hy nou ,,gebind deur die. Gees na Jerusalem gaan". So 'n gebondenheid waarin ek die roepstem van die groot ...

  8. Formation of Hydrochemical River Regime Under Extreme Contamination by Waste Water (the Sak-Elga River in the Chelyabinsk Region)

    Science.gov (United States)

    Denisov, S. E.; Ulrikh, D. V.; Zhbankov, G. O.

    2017-11-01

    Modern technologies designed to use natural resources in different ways are applied to restructure the environment. The use of technologies results in the deformation of environment, its local, regional and global changes occur. In the course of mining the spaces disturbed by the mine opening rock heaps and processing wastes are formed and rapidly appear. These spaces are dead surfaces the negative effect of which extends to the surrounding areas. Thus, the indirect impact on the lands connected with the change of the condition and regime of the surface and groundwater, settling of dust and chemical compounds from emissions to the atmosphere as well as the products of wind and water erosion lead to deterioration in the quality of the lands, surface and groundwater resources in the area affected by mining.

  9. Accountability, Collaboration, and Social Change: Ethical Tensions in an Action Research Project to Address Untested Sexual Assault Kits (SAKs).

    Science.gov (United States)

    Campbell, Rebecca; Fehler-Cabral, Giannina

    2017-12-01

    We conducted a collaborative action research project with stakeholders in Detroit, Michigan, to develop long-term policy strategies to resolve ~11,000 untested rape kits that were discovered in a police storage facility in August 2009. In our research, we uncovered overwhelming evidence of victim-blaming behaviors and fundamental disrespect of rape survivors by the police, which directly contributed to their decisions not to submit kits for forensic testing. We had an ethical responsibility to report these negative findings accurately and completely, and in doing so, we were concerned that police stakeholders might disengage from the action research project and hamper our other ethical responsibilities to promote general and public welfare. In this article, we examine the ethical challenges of balancing accountability, collaboration, and social change. © Society for Community Research and Action 2017.

  10. Ümberkujundava juhtimise karismaatiline aspekt ja selle tõhusus / Kulno Türk, Gerda Mihhailova

    Index Scriptorium Estoniae

    Türk, Kulno, 1954-

    2004-01-01

    Autorite arvates ei tohi vastandada klassikalist juhtimist eestvedamisele ning juhi ja liidri rollid on mõlemad olulised organisatsiooni edukuse eeldused. Edukas juht peab kasutama tasakaalustatult erinevaid juhtimisstiile. Skeem

  11. Kognitiivsete ja metakognitiivsete õpistrateegiate toetamine tehnoloogiaga tõhustatud keeleõppes / Katrin Saks, Äli Leijen

    Index Scriptorium Estoniae

    Saks, Katrin, 1968-

    2015-01-01

    Tehnoloogiliste vahenditega tõhustatud võõrkeelekursuse raames välja töötatud sekkumisest, mis võimaldab õpetajal parimal moel toetada õppijate kognitiivseid ja metakognitiivseid keele- õppestrateegiaid

  12. Kuriteoohvrite abistamisest Eestis : [bakalaureusetöö] / Gerda Sepp ; Tartu Ülikool, õigusteaduskond ; juhendaja: Silvia Kaugia

    Index Scriptorium Estoniae

    Sepp, Gerda

    2009-01-01

    Viktimoloogia mõistest ja olemusest, kuritegevusest Eestis viimasel viiel aastal, kuriteo negatiivsest mõjust selle ohvrile, ohvrite reaalsetest võimalustest abisaamiseks praeguses Eestis, hinnangust ohvriabi süsteemile Eestis

  13. Charismatic aspect of transformational leadership and its role in creating organizational culture / Gerda Mihhailova, Kulno Türk

    Index Scriptorium Estoniae

    Mihhailova, Gerda

    2006-01-01

    Ettevõtte kasvu- ja küpsusfaasis vajatakse autorite hinnangul enam nn. klassikalisi juhte, karismaatilised juhid sobivad pigem radikaalseid muutusi nõudvatesse situatsioonidesse, nagu näiteks ettevõtte rajamine või selle langusfaasist välja toomine. Skeemid. Tabel. Lisa lk. 194

  14. Kelle nimel NO99 seekord kõneleb ja kelle poole pöördub? / Valle-Sten Maiste, Gerda Kordemets, Madli Pesti...[jt.

    Index Scriptorium Estoniae

    2011-01-01

    23. märtsil esietendub Nokia kontserdimajas NO99 lavastus"The Rise and Fall of Estonia", mis saab olema Eesti-teemaliste lavastuste tsükli lõpp. Lavastajad Ene-Liis Semper ja Tiit Ojasoo. Eesti teatrikriitikute ühendus tegi eksperimendi ja otsustas oma teatrimuljed kohe jäädvustada: esietendusjärgsel hilisõhtul vestlesid lavastusest erinevad eesti teatrikriitikud

  15. Cloning, high-level expression, purification and characterization of a ...

    African Journals Online (AJOL)

    The staphylokinase (Sak) is emerging as an important thrombolytic agent for the treatment of patients suffering from cardiovascular disease. Hence in this study, we reported the cloning, high-level expression, purification and characterization of the Sak variant SakøC from Staphylococcus aureus QT08 in Escherichia coli ...

  16. Això és la Guerra i Gerda Taro. El compromís narratiu de la fotografia mplicada del segle XX: retrospectiva de dos fotoperiodistes de la Guerra Civil espanyola al MNAC

    OpenAIRE

    Bellati, Ilaria

    2010-01-01

    L’exposició es divideix en sis espais on les imatges de Robert Capa mostren importants i decisius escenaris de guerra de la primera meitat de segle. En l’etapa compresa entre el 1930 i el 1945 el fotògraf va viatjar a Espanya per donar cobertura al començament de la Guerra Civil, va anar a la Xina per retratar la Segona Guerra Sinojaponesa i finalment va tornar a Espanya per presenciar el final de la Guerra Civil espanyola a Catalunya. L’any 1944 assistí a les operacions del desembarcament de...

  17. Oceanographic profile temperature, salinity, oxygen, and nutrients measurements collected using bottle from the LCM Red in the Alaskan Coastal waters, from the Gerda in the Atlantic Ocean, and from DeSteiguer in the Pacific Ocean (NODC Accession 0002231)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Temperature, salinity, oxygen and other profile data received at NODC on 06/10/04 by Olga Baranova, digitized from "William J. Teague, Zachariah R. Hallock, Jan M....

  18. "Klass : elu pärast" võitis rahvusvahelisel festivalil peaauhinna

    Index Scriptorium Estoniae

    2009-01-01

    Genfis toimunud rahvusvahelisel festivalil Cinema Tous Ecrans sai telesarjade võistlusprogrammis peaauhinna ETV sari "Klass : elu pärast", produtsent Gerda Kordemets, stsenarist Margit Keerdo, režissöörid Ilmar Raag, Gerda Kordemets, Liina Paakspuu, Priit Valkna ja Marek Miil

  19. "Klass : elu pärast" võitis peaauhinna

    Index Scriptorium Estoniae

    2009-01-01

    Genfis toimunud rahvusvahelisel festivalil Cinema Tous Ecrans sai telesarjade võistlusprogrammis peaauhinna ETV sari "Klass : elu pärast", produtsent Gerda Kordemets, stsenarist Margit Keerdo, režissöörid Ilmar Raag, Gerda Kordemets, Liina Paakspuu, Priit Valkna ja Marek Miil

  20. Værk og værksted

    DEFF Research Database (Denmark)

    Kjølsen, Tine; Gammelgaard, Jørgen

    2012-01-01

    Gerda Thune Andersen – Værk og Værksted Bogen er udgivet i forbindelse med jubilæumsudstillingen på Vendsyssel Kunstmuseum 31 august – 25 november 2012. Udstillingen er blevet til i et samarbejde mellem Vendsyssel Kunstmuseum og Gerda Thune Andersen. Tak til: Jørgen Gammelgaard, Tine Kjølsen, Ann...

  1. Specificity of Structural Assessment of Knowledge

    Science.gov (United States)

    Trumpower, David L.; Sharara, Harold; Goldsmith, Timothy E.

    2010-01-01

    This study examines the specificity of information provided by structural assessment of knowledge (SAK). SAK is a technique which uses the Pathfinder scaling algorithm to transform ratings of concept relatedness into network representations (PFnets) of individuals' knowledge. Inferences about individuals' overall domain knowledge based on the…

  2. ORF Alignment: NC_003923 [GENIUS II[Archive

    Lifescience Database Archive (English)

    Full Text Available NC_003923 gi|21283614 >2sak0 1 121 43 163 1e-41 ... dbj|BAB95750.1| STAPHYLOKINASE PRECURSOR [Stap...hylococcus aureus subsp. aureus MW2] ... ref|NP_646702.1| STAPHYLOKINASE PRECURSOR ... [Stap...hylococcus aureus subsp. aureus MW2] ... sp|Q8NVR2|SAK_STAAW Staphylokinase precursor ...

  3. Uus film tegi Raagist tegija / Andres Keil

    Index Scriptorium Estoniae

    Keil, Andres, 1974-

    2005-01-01

    Eesti Televisiooni fiktiivne dokumentaaldraama "August 1991" : stsenarist ja režissöör Ilmar Raag : produtsent Gerda Kordemets : operaator Janno-Hans Arro. Lisatud augustiputshi ajal teletorni kaitsnud Jüri Joosti ja Peeter Milli kommentaar

  4. Kalev Kesküla kirjutab stsenaariumi restoranist Gloria

    Index Scriptorium Estoniae

    2007-01-01

    Ajalehe EE kirjandustoimetaja kirjutab stsenaariumi teemal "70 aastat head elu Eestis ehk 70 aastat Tallinna nautleja elust", filmi režissöör Ilmar Raag, idee autor Dimitri Demjanov, produtsent Gerda Kordemets

  5. New generation in Estonian animation / Mari-Liis Rebane

    Index Scriptorium Estoniae

    Rebane, Mari-Liis, 1988-

    2010-01-01

    Eesti animafilmide loojate uuest põlvkonnast, animafilmide tegemise võimalustest, uute animafilmide tasemest. Martinus Daane Klemeti animafilmidest "Furry Flurry" (2006) ja "Light My Fire" (2007) ning joonisfilmist "Õhus" (Eesti Joonisfilm, 2009, kunstnik Gerda Märtens)

  6. Association of the pitch canker pathogen Fusarium circinatum with ...

    African Journals Online (AJOL)

    Association of the pitch canker pathogen Fusarium circinatum with grass hosts in commercial pine production areas of South Africa. Cassandra L Swett, Bernice Porter, Gerda Fourie, Emma T Steenkamp, Thomas R Gordon, Michael J Wingfield ...

  7. Re-use of seedling containers and Fusarium circinatum association ...

    African Journals Online (AJOL)

    Re-use of seedling containers and Fusarium circinatum association with asymptomatic Pinus patula planting stock. Andrew R Morris, Gerda Fourie, Izette Greyling, Emma T Steenkamp, Nicoletta B Jones ...

  8. In Vitro Characterization of a Multifunctional Staphylokinase Variant with Reduced Reocclusion, Produced from Salt Inducible E. coli GJ1158

    Directory of Open Access Journals (Sweden)

    K. K. Pulicherla

    2013-01-01

    Full Text Available The thrombolytic therapy with clinically approved drugs often ensues with recurrent thrombosis caused by thrombin-induced platelet aggregation from the clot debris. In order to minimize these problems, a staphylokinase (SAK-based bacterial friendly multifunctional recombinant protein SRH (staphylokinase (SAK linked with tripeptide RGD and dodecapeptide Hirulog (SRH was constructed to have Hirulog as an antithrombin agent and RGD (Arg-Gly-Asp as an antiplatelet agent in the present study. This multifunctional fusion protein SRH was expressed in osmotically inducible E. coli GJ1158 as soluble form and purified with a yield of 0.27 g/L and functionally characterized in vitro. SRH retained the fibrinolytic activity and plasminogen activation rate comparable to the parental counterpart SAK. The antithrombin activity of SRH was significantly higher than SAK. The platelet rich clot lysis assay indicated that SRH had enhanced platelet binding activity and T50% and C50 of SRH were significantly lower than that of SAK. Furthermore, SRH inhibited the ADP-induced platelet aggregation in dose-dependent manner while SAK had no significant effect on platelet aggregation. Thus, the current study suggests that the SAK variant produced from osmotically inducible GJ1158 is more potent thrombolytic agent with antithrombin and antiplatelet aggregation activities for reduction of reocclusion in thrombolytic therapy.

  9. Kak reshit problemu bezgrazhdanstva?

    Index Scriptorium Estoniae

    2003-01-01

    Erakondade kodakondsuspoliitikast räägivad: Tiit Toomsalu - ESDTP, Andrei Arjupin - EÜVRP, Sergei Ivanov - Reformierakond, Katrin Saks - Rahvaerakond Mõõdukad, Tiit Matsulevitsh - Res Publica, Nikolai Maspanov - VEE, Vladimir Velman - Keskerakond. Valimiseelne debatt

  10. Talbott rõhutab sotsiaalset integratsiooni / Strobe Talbott ; interv. Erkki Bahovski

    Index Scriptorium Estoniae

    Talbott, Strobe

    2000-01-01

    Eesti ühinemine NATO-ga, EL-iga, USA-Venemaa suhted, OSCE missiooni vajalikkus Eestis. Regionaalse julgeoleku printsiibid. Kommenteerivad: Harri Tiido, Tarmo Kõuts, Katrin Saks, Toomas Hendrik Ilves

  11. Eduard Odinets : "Olen eestlane, kelle emakeel on vene keel" / Eduard Odinets ; interv. Erik Kalda

    Index Scriptorium Estoniae

    Odinets, Eduard, 1976-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje Ilmunud ka: Severnoje Poberezhje : Subbota 3. juuni lk. 3. Riigikogu sotsiaaldemokraatide fraktsiooni nõunik oma poliitikukarjäärist. Arvamust avaldab Katrin Saks ja Meelis Goldberg (Severnoje Pob.)

  12. Kolm kiitust eesti graafikale / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    1999-01-01

    Graafik Benjamin Vassermanni loomingust, näitustest ja saadud auhindadest. Rahvusvahelisel Orense graafikabiennaalil 1998. a. said kolm eesti graafikut (B. Vassermann, V. Tolli, R. Saks) kiituse osaliseks. B. Vassermannilt oli töö 'Kaalutlus'

  13. Eesti graafikute edu Hispaanias

    Index Scriptorium Estoniae

    1999-01-01

    Hispaanias Orenses toimunud V rahvusvahelisel graafikabiennaalil (dets. 1998/jaan. 1999) pälvisid kiituse koos rahalise preemiaga Reti Saks, Vive Tolli, Benjamin Vasserman. Julio Prieto Naspereira auhinna žüriilt I preemia Tamoya Uchidale Jaapanist

  14. International conference "Cultural Plurality in Estonia : Policies and Solutions"

    Index Scriptorium Estoniae

    2000-01-01

    Ettekandjad: Katrin Saks, Mall Hellam, Mati Luik, Kirsti Häkkinen, Vello Pettai, Ivi Proos, Katri Raik, NiinaOrhimenko, Ib Ostergaard Rasmussen, Urve Läänemets, Jüri Valge, Aleksander Dusman, Raivo Juurak, Rein Ruutsoo

  15. On Zweier Sequence Spaces and de la Vall\\'{e}e-Poussin mean of order $\\alpha$

    Directory of Open Access Journals (Sweden)

    Bipan Hazarika

    2016-07-01

    Full Text Available The main purpose of this paper is to study some geometrical properties such as order continuous, the Fatou property and the Banach-Saks property of the new space $[\\mathcal{Z}_{\\lambda}^{\\alpha}]_{\\infty}(p.$

  16. Reval Hotel Lietuva Vilniuses : Konstitucijos pr. 20 / Piret Lindpere

    Index Scriptorium Estoniae

    Lindpere, Piret, 1963-

    2004-01-01

    Vilniuse hotelli "Lietuva" renoveerimine. Arhitektuurse projekti koostaja Rootsi arhitektuuribüroo AB SWECO (arhitektid Aare Saks, Nils Palm. Sisekujundus: Vaikla Disain AS (Katrin ja Argo Vaikla, Liis Lindvere, Peeter Loo). Kommenteerivad Argo ja Katrin Vaikla. 3 ill

  17. Expression of recombinant staphylokinase in the methylotrophic yeast Hansenula polymorpha

    Directory of Open Access Journals (Sweden)

    Moussa Manal

    2012-12-01

    Full Text Available Abstract Background Currently, the two most commonly used fibrinolytic agents in thrombolytic therapy are recombinant tissue plasminogen activator (rt-PA and streptokinase (SK. Whereas SK has the advantage of substantially lower costs when compared to other agents, it is less effective than either rt-PA or related variants, has significant allergenic potential, lacks fibrin selectivity and causes transient hypotensive effects in high dosing schedules. Therefore, development of an alternative fibrinolytic agent having superior efficacy to SK, approaching that of rt-PA, together with a similar or enhanced safety profile and advantageous cost-benefit ratio, would be of substantial importance. Pre-clinical data suggest that the novel fibrinolytic recombinant staphylokinase (rSAK, or related rSAK variants, could be candidates for such development. However, since an efficient expression system for rSAK is still lacking, it has not yet been fully developed or evaluated for clinical purposes. This study’s goal was development of an efficient fermentation process for the production of a modified, non-glycosylated, biologically active rSAK, namely rSAK-2, using the well-established single cell yeast Hansenula polymorpha expression system. Results The development of an efficient large scale (80 L Hansenula polymorpha fermentation process of short duration for rSAK-2 production is described. It evolved from an initial 1mL HTP methodology by successive scale-up over almost 5 orders of magnitude and improvement steps, including the optimization of critical process parameters (e.g. temperature, pH, feeding strategy, medium composition, etc.. Potential glycosylation of rSAK-2 was successfully suppressed through amino acid substitution within its only N-acetyl glycosylation motif. Expression at high yields (≥ 1g rSAK-2/L cell culture broth of biologically active rSAK-2 of expected molecular weight was achieved. Conclusion The optimized production process

  18. The problem of untested sexual assault kits: why are some kits never submitted to a crime laboratory?

    Science.gov (United States)

    Patterson, Debra; Campbell, Rebecca

    2012-07-01

    Victims of sexual assault are often advised to seek postassault medical care to have a forensic exam, which includes evidence collection (termed a sexual assault kit [SAK]). After the exam, law enforcement personnel are supposed to submit the SAK to a crime laboratory for analysis. However, recent media reports suggest that in many communities throughout the United States, thousands of SAKs are left untested. Few studies have examined the rate at which law enforcement submits SAKs to crime labs or the factors that may predict them to do so. Thus, the purpose of this exploratory study is twofold: (a) to examine the percentage of SAKs law enforcement submits to crime labs in cases in which a sexual assault nurse examiner (SANE) performed the exam with adult victims and (b) to explore whether assault and law enforcement characteristics predict whether SAKs are submitted to a crime lab. This study found that only 58.6% of the SAKs were submitted to the crime lab within a large Midwestern county. Using binary logistic regression, this study found that kits were significantly as likely to be submitted when there were documented physical (nonanogenital) injuries compared with kits that did not have documented physical injuries. In addition, kits that were handled by a law enforcement agency that had a high level of engagement with the SANE program were significantly as likely to be submitted as law enforcement agencies with a low or medium level of engagement. Kits were significantly less likely to be submitted when victims cleaned themselves after the sexual assault (e.g., bathing). No association was found between kit submission and the victim-offender relationship, suspected drug-facilitated sexual assault, anogenital injury, and when the victim consumed alcohol or drugs before the assault. This article concludes with a discussion of the implications for research and practice.

  19. "August 1991" - film ajaloost ja teletöötajaist / Sergo Selder

    Index Scriptorium Estoniae

    Selder, Sergo

    2005-01-01

    Eesti Televisiooni fiktiivne dokumentaaldraama "August 1991" : stsenarist ja režissöör Ilmar Raag : produtsent Gerda Kordemets : operaator Janno-Hans Arro. "Prototüübid" Enn Eesmaa ja Andres Raid kommenteerivad endi ja kolleegide kujutamist filmis

  20. Techniques to distinguish between electron and photon induced events using segmented germanium detectors

    Energy Technology Data Exchange (ETDEWEB)

    Kroeninger, K.

    2007-06-05

    Two techniques to distinguish between electron and photon induced events in germanium detectors were studied: (1) anti-coincidence requirements between the segments of segmented germanium detectors and (2) the analysis of the time structure of the detector response. An 18-fold segmented germanium prototype detector for the GERDA neutrinoless double beta-decay experiment was characterized. The rejection of photon induced events was measured for the strongest lines in {sup 60}Co, {sup 152}Eu and {sup 228}Th. An accompanying Monte Carlo simulation was performed and the results were compared to data. An overall agreement with deviations of the order of 5-10% was obtained. The expected background index of the GERDA experiment was estimated. The sensitivity of the GERDA experiment was determined. Special statistical tools were developed to correctly treat the small number of events expected. The GERDA experiment uses a cryogenic liquid as the operational medium for the germanium detectors. It was shown that germanium detectors can be reliably operated through several cooling cycles. (orig.)

  1. The impact of telecommuting on the division of labour in the domestic setting

    NARCIS (Netherlands)

    Casimir, G.J.

    2001-01-01

    When people start working at home, it is plausible that the division of labour within the home will change, in particular the division between men and women. Gerda Casimir studied these changes, by analysing the results of an Internet survey, to which 171 respondents reacted. The core of

  2. Insider-outsider perspectives of participant observation.

    Science.gov (United States)

    Bonner, Ann; Tolhurst, Gerda

    2002-01-01

    Ann Bonner and Gerda Tolhurst provide personal accounts of their experiences in conducting research involving participant observation. Issues discussed include the advantages and disadvantages of nurse researchers as insiders and outsiders. Also considered are strategies used to overcome both researcher effect and participant response to the researcher.

  3. Browse Title Index

    African Journals Online (AJOL)

    Items 1 - 50 of 181 ... Vol 28, No 3 (2010), An analysis of family-school collaboration in preventing adolescent violence in urban secondary schools, Abstract. CJ Gerda Bender ... Vol 28, No 2 (2010), Balance in academic leadership: Voices of women from Turkey and the United States of America (US), Abstract. O Hacifazlioğlu.

  4. Bruno 2016 / Karin Paulus

    Index Scriptorium Estoniae

    Paulus, Karin, 1975-

    2016-01-01

    Valik disainiauhinnale Bruno 2016 kandideerivatest esemetest (Gerda Retter "Jääkideta nahadisain", Raul Abner "Kummut Mix", Argo Ader ja Rain Aduson "Fitbi - spordi mugavalt!", Merili Sulg "Seinašabloon Kasemets", Rita Assor "Lugemispesa-mänguala Aas", Mare Kelpman "Terra pleedid", Henri Viljarand "Vineervalamu Gniss")

  5. Impact of Lactobacillus curvatus 54M16 on microbiota composition and growth of Listeria monocytogenes in fermented sausages.

    Science.gov (United States)

    Giello, Marina; La Storia, Antonietta; De Filippis, Francesca; Ercolini, Danilo; Villani, Francesco

    2018-06-01

    Lactobacillus curvatus 54M16 produced bacteriocins sak X, sak T α , sak T β and sak P. The aim of this study was to investigate the anti-listerial activity of the bacteriocins-producing strain against Listeria monocytogenes in vitro co-culture experiments and during the manufacture of fermented sausages. In MRS broth, Lb. curvatus 54M16 was able to inhibit L. monocytogenes to undetectable levels after 48 h at 20 °C or 5 days at 15 °C. Anti-listerial activity was lower during the production of fermented sausages with pathogen inoculation at levels of approximately 4 Log CFU g -1 . However, total inhibition of L. monocytogenes native to the raw ingredients was achieved over the course of the fermentation. Moreover, 16S rRNA-based analysis revealed the ability of Lb. curvatus 54M16 to dominate and affect the bacterial ecosystem, whereas spoilage-associated bacterial genera, such as Brochothrix, Psychrobacter, Pseudomonas and some Enterobacteriaceae, were found until the end of ripening in sausages without Lb. curvatus 54M16. The use of the bacteriocins-producing Lb. curvatus 54M16 in fermented sausages could be an important contribution to product safety, provided that eco-physiological factors and other preservation methods are maintained at levels required for the inhibition of pathogens in controlled conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Isolating highly connected induced subgraphs

    DEFF Research Database (Denmark)

    Penev, Irena; Thomasse, Stephan; Trotignon, Nicolas

    2016-01-01

    the existence of a highly connected subgraph. We give several variants of our result, and for each of these variants, we give asymptotics for the bounds. We also compute optimal values for the case when k = 2. Alon, Kleitman, Saks, Seymour, and Thomassen proved that in a graph of high chromatic number...

  7. Arvutijuhtimisega korter annab omanikule kontrolli / Siiri Suutre

    Index Scriptorium Estoniae

    Suutre, Siiri

    2007-01-01

    Järgmisel aastal valmib Tallinnas Juurdeveo 19 maja, kus korteriomanikel on pidev virtuaalne juurdepääs oma kodule. Projekteerijad Harry Klaar ja Kätlin Saks arhitektuuribüroost On Arhitektid. Tehnoloogiline lahendus AS Eltron ja Yoga Intelligence AS

  8. Eesti graafika edu Hispaanias / Benjamin Vasserman

    Index Scriptorium Estoniae

    Vasserman, Benjamin

    1999-01-01

    Hispaanias Orenses dets. 1998/jaan. 1999 peetud V rahvusvahelisel graafikabiennaalil "Julio Prieto Nespereira auhind" pälvisid žürii kiituse eesti graafikud R. Saks, V. Tolli, B. Vasserman. I preemia ئ T. Uchida. Näitusel osales S. Liiva. 1998. a. sügisel Jaapanis toimunud II Tokio rahvusvahelisest väikegraafika triennaalist võttis osa N. Neidre.

  9. Macroscopic modelling of solid-state fermentation

    NARCIS (Netherlands)

    Hoogschagen, M.J.

    2007-01-01

    Solid-state fermentation is different from the more well known process of liquid fermentation because no free flowing water is present. The technique is primarily used in Asia. Well-known products are the foods tempe, soy sauce and saké. In industrial solid-state fermentation, the substrate usually

  10. A New Difference Sequence Set of Order α and Its Geometrical Properties

    Directory of Open Access Journals (Sweden)

    Mikail Et

    2014-01-01

    Full Text Available We introduce a new class of sequences named as mαΔr,ϕ,p and, for this space, we study some inclusion relations, topological properties, and geometrical properties such as order continuous, the Fatou property, and the Banach-Saks property of type p.

  11. Valitsejad püsinud aasta otsa pukis / interv. Enno Tammer

    Index Scriptorium Estoniae

    2000-01-01

    Küsimustele, mis puudutavad valitsuse saavutusi ja probleeme, vastavad valitsuse liikmed M. Laar, J. Luik, T. Loodus, T. Lukas, T. Jürgenson, S. Kallas, M. Rask, S. Kivi, H. Kranich, T. Asmer, T.-H. Ilves, E. Nestor, M. Pärnoja, I. Padar, K. Saks

  12. Benjamin Vassermanile preemiad

    Index Scriptorium Estoniae

    2007-01-01

    Graafik Benjamin Vasserman pälvis kolme digitaalse graafilise lehe eest žürii kiituse Ungaris Györis toimunud biennaalil "The Master of Drawing and Graphic Arts" ning II preemia nelja lehe eest Leedus Vilniuses toimunud VI rahvusvahelisel väikegraafika triennaalil. Eestist osalesid veel Reti Saks ja Kelli Valk

  13. President Lennart Meri : tuleviku Eestis võiks rahvas riigipead otse valida / Lennart Meri ; intervjueerinud Urmas Klaas

    Index Scriptorium Estoniae

    Meri, Lennart, 1929-2006

    2000-01-01

    Oma viimast valitsemisaastat alustanud president Lennart Meri teeb ülevaate lahendamist ootavatest probleemidest. Intervjuus tõstatatud probleeme kommenteerivad: S. Oviir, T. Tammsaar, T. Kivimägi, H. Maasel, K. Saks, T. Asmer. Parlamendisaadik (S. Oviir, T. Tammsaar). Ilmunud ka: Molodjozh Estonii 7. okt. lk. 8-9

  14. Brüsselis tõlkijatööd katsetamas / Liina Ristoja

    Index Scriptorium Estoniae

    Ristoja, Liina

    2010-01-01

    Üle-Euroopalise noorte tõlkevõistluse Juvenes Translatores võitis 27 noort, kelle seas olid ka Gustav Adolfi Gümnaasiumi õpilane Reti Maria Vahtrik ja Luksemburgi Euroopa Koolis õppiv Seio Saks. Noored saadeti Brüsselisse auhinnareisile

  15. Reval Hotel Lietuva / Argo Vaikla

    Index Scriptorium Estoniae

    Vaikla, Argo, 1966-

    2004-01-01

    Vilniuse hotelli "Lietuva" renoveerimine. Arhitektuurne renoveerimisprojekt: Aare Saks, Nils Palm (SWECO FFNS Arkitekter AB, Rootsi), Rolandas Palekas (UAB Viltekta). Sisekujundus: Katrin ja Argo Vaikla, Liis Lindvere, Peeter Loo (Vaikla Disain AS). Ehitaja: Merko Statyba UAB. Projekt 2002, valmis 2003. I korruse plaan, välisvaade, 4 sisevaadet

  16. Burnout and work engagement of South African blue-collar workers ...

    African Journals Online (AJOL)

    blue-collar workers in different industries in South Africa (N=2769). Following scale development ... and job satisfaction (Harter, Hayes & Schmidt 2002; Saks 2006; Schaufeli & Bakker. 2004a; Siu, Phillips & Leung .... job demands/job resources and psychological well-being (burnout and engagement) is driven by two very ...

  17. Download this PDF file

    African Journals Online (AJOL)

    DR. AMIN

    Gadagi” tea preparations,. “sak'',”sada” and “magani”.. LD50 values of each type of the tea were determined. Results of phase. I and phase II of the study showed no mortality was recorded in any of the experimental groups of rats in 24hours ...

  18. Metamemory, Memory Performance, and Causal Attributions in Gifted and Average Children.

    Science.gov (United States)

    Kurtz, Beth E.; Weinert, Franz E.

    1989-01-01

    Tested high- and average-achieving German fifth- and seventh-grade students' metacognitive knowledge, attributional beliefs, and performance on a sort recall test. Found ability-related differences in all three areas. Gifted children tended to attribute academic success to high ability while average children attributed success to effort. (SAK)

  19. Segarühm Kehtna Noored sündis soovist tantsida / Tiia Truu, Heino Laiapea

    Index Scriptorium Estoniae

    Truu, Tiia, 1948-

    2009-01-01

    Tänavusel laulu- ja tantsupeol ÜhesHingamine osalevate kollektiivide tutvustus. Rahvatantsurühmast Kehtna Noored (juhendaja Mall Niinemets), Valtu põhikooli võimlejatest (juhendaja Kadi Saks), rahvatantsurühmast Kärutajad (juhendaja Valdo Rebane), Kehtna segakoorist (dirigent Ülle Eerik), Kehtna valla lastekoorist (dirigendid Lea Karjane ja Ea Hark)

  20. Kolm meest, kes ostsid Thulema / Koit Brinkmann

    Index Scriptorium Estoniae

    Brinkmann, Koit

    2006-01-01

    Mööblifirma Thulemast 60% ostnud Wallenium Grupp OÜ omanikud Henri Rüüsak, Endrus Arge ja Sparry Kivilo tahavad ettevõttest teha Baltimaade suurima mööblitootja. Diagramm. Kommenteerivad Jussi Aine, August Kull, Siiri Maask ja Tõnis Tarbe

  1. A New Measurement of Scientific Creativity: the Study of its Psychometric Properties

    Directory of Open Access Journals (Sweden)

    María-Rosario Bermejo

    Full Text Available The purpose of this paper is to study the psychometric proprieties of a new test aimed to measure scientific creativity, the Creative Scientific Ability Test (C-SAT, Sak & Ayas, 2011. The test has been validated in different Turkish samples, showing an adequate reliability (α = .87, Ayas & Sak, 2014. The test is composed of five tasks that measure scientific creativity in different areas of knowledge: Biology, Chemistry, Physics, Ecology and an interdisciplinary task. For each task, a Creative Quotient (CQ is calculated as a combination of Fluency (number of valid answers and Flexibility (different approaches in the solution. The test also allows us to differentiate three scientific-creative thinking processes (hypothesis generation, hypothesis evaluation and evidence verification. 344 students from Compulsory Secondary Education took part in this study. The results point out a good reliability (α = .705 and an adequate inter-rater agreement (ranging from average ICC .80 to .98. In addition, the unifactorial structure of the test was verified using CFA, which agree with the authors' previous results (Ayas & Sak, 2014; Sak & Ayas, 2013, even when a structure of three creative process can be considered.

  2. Trachypodaceae. A critical revision

    NARCIS (Netherlands)

    Zanten, van B.O.

    1959-01-01

    1. Trachypus. 1. T. bicolor Reinw. et Hornsch. is divided into 4 varieties: a. var. bicolor, b. var. hispidus (C. Muell.) Card., c. var. viridulus (Mitt.) Zant. comb. nov., d. var. scindifolius (Sak.) Nog. 2. T. humilis Lindb. is divided into 2 varieties: a. var. humilis, b. var. tenerrimus (Herz.)

  3. AL FIKR AL BALAGHI FI AL MA’ĂNI ‘INDA AS SAKĂKI FI KITABIHI MIFTAHUL ULUM DIRĂSAH BALAGHIYYAH

    Directory of Open Access Journals (Sweden)

    Talqis Nurdianto

    2018-02-01

    Full Text Available Miftāhul ‘Ulūm, written by al-Sakākī, especially the third part, was the beginning of a new phase in the development of Arabic rhetoric. Al-Sakākī divided the rhetoric into three fields of study, which are  (1 Ma’ānī, (2 Bayān, (3 Badī’. However, his style is influenced by philosophers, theologians and their verbal lexicon, which are difficult to take, especially for the ordinary recipient. Al-Sakākī described that his book containing several types of literature, namely, ‘ilm ṣarf in complete version and its conclusion, derivation science, and the grammatical study in the completeness of Ma’ānī and Bayān. The meaning of Makna is the study of completeness and conclusion. Therefore, books and prose, and poem require al-‘Arūḍ and al-Qawāfī include Ṣarf, Grammar, Ma’ānī, Bayān, limitation, reasoning, al’Arūḍ, and al-Qawāfī. He argued that the fields of study were influential in delivering knowledge to the student in order to reach the goal of the author towards his book.This research was an analytical descriptive study of al-Sakākī rhetoric that focused on the normative aspect represented by rhetorical rule and aesthetic aspects. Those aspects were shown by the feeling. Al-Sakākī rhetoric thought is a method based on mental division and has conducted in the construction of many factors, which the most important of them are philosophy and logic. Keywords: thought, rhetoric, meanings, sakkaki, study

  4. Synergetic effect of yihuo qingyi decoction (see text) and recombinant staphylokinase in treatment of severe acute pancreatitis of rats.

    Science.gov (United States)

    Chen, Yong-Feng; Sha, Jian-Ping; Wu, Zhong-Min

    2011-06-01

    To investigate the effect of recombinant staphylokinase (r-Sak) and the Chinese medicine Yihuo Qingyi Decoction ((see test) Herbal decoction for severe acute pancreatitis) in the treatment of the severe acute pancreatitis (SAP) in rats, and to observe the synergistic effect of the two. One hundred and sixty-two adult male SD rats with the body mass of 250-280 g were randomly divided into the following 5 groups: sham operation group (n = 18), control group (n = 36), Yihuo Qingyi Decoction treatment group (n = 36), r-Sak treatment group (n = 36), and Yihuo Qingyi Decoction plus r-Sak treatment group (n = 36). The SAP ratmodel was prepared by retrograde injection of 5% sodium taurocholate into the cholangiopancreatic duct. Two days before modeling, Yihuo Qingyi Decoction was intragastrically administrated, and r-Sak was intraperitoneally injected. The survival rate within 18 h after modeling was determined. The pancreatic blood flow, the weight of ascites, and the serum amylase and lipase were investigated at 6 h, 12 h, and 18kh after modeling, and the pancreatic tissue was examined under light microscopy to see its pathological change. The 18 h survival count of group A, B, C, D and E rats was 9, 2, 6, 7 and 8 respectively. After r-Sak and Yihuo Qingyi Decoction intervention, the serum amylase and lipase and the weight of ascites were significantly decreased, especially in group E.18 h after modeling, the level of the serum amylase and lipase and the weight of ascites in group E was 1 100 +/- 118 U x L(-1), 1 000 +/- 150 U x L(-1) and 13.40 +/- 1.80 g respectively, obviously lower than that of group B (P effect between the two.

  5. JPRS Report, Latin America.

    Science.gov (United States)

    1987-07-21

    Sold to PRC 40 Fuel Prices Increase 40 Fiat Suspends Investment 40 Demonstrations Against Hunger, Unemployment Reported (Juanita Rojas; ANALISIS ...basin. The YPF well, Ch. PCe.x.-l ( Puesto Gerda), located in the northwestern sector of the area reserved for the state enterprise, produced 18 cubic...40 CHILE DEMONSTRATIONS AGAINST HUNGER, UNEMPLOYMENT REPORTED Santiago ANALISIS in Spanish 8-14 Jun 87 pp 14-16 [Article by Juanita

  6. Fookuses on lugemine : üks küsimus ajakirja "Raamatukogu" toimetuskolleegiumi liikmeile / Anneli Sepp, Hele Ellermaa, Mihkel Volt ... [jt.

    Index Scriptorium Estoniae

    2010-01-01

    Vastavad ERÜ esimees Anneli Sepp, Kõrveküla raamatukogu direktor Hele Ellermaa, Eesti Rahvusraamatukogu teadus- ja arenduskeskuse juhataja Mihkel Volt, Tartu Ülikooli Raamatukogu käsikirjade ja haruldaste raamatute osakonna juhataja Malle Ermel, Tartu Ülikooli Viljandi Kultuuriakadeemia infohariduse osakonna juhataja Ilmar Vaaro, Tallinna Ülikooli Akadeemlise Raamatukogu baltika ja haruldaste raamatute osakonna juhataja Katrin Kaugver, Tallinna Tehnikaülikooli Raamatukogu asedirektor Gerda Koidla ja Tartu Lutsu-nimelise Linnaraamatukogu direktor Asko Tamme

  7. NDM06: 2. symposium on neutrinos and dark matter in nuclear physics

    International Nuclear Information System (INIS)

    Akerib, D.; Arnold, R.; Balantekin, A.; Barabash, A.; Barnabe, H.; Baroni, S.; Baussan, E.; Bellini, F.; Bobisut, F.; Bongrand, M.; Brofferio, Ch.; Capolupo, A.; Carrara Enrico; Caurier, E.; Cermak, P.; Chardin, G.; Civitarese, O.; Couchot, F.; Kerret, H. de; Heros, C. de los; Detwiler, J.; Dracos, M.; Drexlin, G.; Efremenko, Y.; Ejiri, H.; Falchini, E.; Fatemi-Ghomi, N.; Finger, M.Ch.; Finger Miroslav, Ch.; Fiorillo, G.; Fiorini, E.; Fracasso, S.; Frekers, D.; Fushimi, K.I.; Gascon, J.; Genest, M.H.; Georgadze, A.; Giuliani, A.; Goeger-Neff, M.; Gomez-Cadenas, J.J.; Greenfield, M.; H de Jesus, J.; Hallin, A.; Hannestad, St.; Hirai, Sh.; Hoessl, J.; Ianni, A.; Ieva, M.B.; Ishihara, N.; Jullian, S.; Kaim, S.; Kajino, T.; Kayser, B.; Kochetov, O.; Kopylov, A.; Kortelainen, M.; Kroeninger, K.; Lachenmaier, T.; Lalanne, D.; Lanfranchi, J.C.; Lazauskas, R.; Lemrani, A.R.; Li, J.; Mansoulie, B.; Marquet, Ch.; Martinez, J.; Mirizzi, A.; Morfin Jorge, G.; Motz, H.; Murphy, A.; Navas, S.; Niedermeier, L.; Nishiura, H.; Nomachi, M.; Nones, C.; Ogawa, H.; Ogawa, I.; Ohsumi, H.; Palladino, V.; Paniccia, M.; Perotto, L.; Petcov, S.; Pfister, S.; Piquemal, F.; Poves, A.; Praet, Ch.; Raffelt, G.; Ramberg, E.; Rashba, T.; Regnault, N.; Ricol, J.St.; Rodejohann, W.; Rodin, V.; Ruz, J.; Sander, Ch.; Sarazin, X.; Scholberg, K.; Sigl, G.; Simkovic, F.; Sousa, A.; Stanev, T.; Strolger, L.; Suekane, F.; Thomas, J.; Titov, N.; Toivanen, J.; Torrente-Lujan, E.; Tytler, D.; Vala, L.; Vignaud, D.; Vitiello, G.; Vogel, P.; Volkov, G.; Volpe, C.; Wong, H.; Yilmazer, A.

    2006-01-01

    This second symposium on neutrinos and dark matter is aimed at discussing research frontiers and perspectives on currently developing subjects. It has been organized around 6 topics: 1) double beta decays, theory and experiments (particularly: GERDA, MOON, SuperNEMO, CUORE, CANDLES, EXO, and DCBA), 2) neutrinos and nuclear physics, 3) single beta decays and nu-responses, 4) neutrino astrophysics, 5) solar neutrino review, and 6) neutrino oscillations. This document is made up of the slides of the presentations

  8. Isolation and identification of euphol and ß-sitosterol from the dichloromethane extracts of Synadenium glaucescens

    CSIR Research Space (South Africa)

    Nyigo, VA

    2016-06-01

    Full Text Available 2016; 5(3): 100-104May- June© 2016, All rights reserved Isolation and identification of euphol and β-sitosterol from the dichloromethane extracts of Synadenium glaucescens Vitus A. Nyigo, Xolani Peter, Faith Mabiki, Hamisi M. Malebo, Robinson H.... Mdegela, Gerda Fouche 1: Department of Veterinary Medicine and Public Health, Sokoine University of Agriculture, P.O. Box 3021 Morogoro, Tanzania 2: Department of Traditional Medicine Research, National Institute for Medical Research, 3 Barack Obama...

  9. Neutrinoless double beta decay searches with 76Ge

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    The search for neutrinoless double beta decay might be the only window to observe lepton number violation. Its observation would favour the leptogenesis mechanism for the explanation of the baryon asymmetry of the universe and is therefore considered to be of highest relevance. The isotope 76Ge has historically been most important for this search and the ongoing experiment GERDA has the lowest background of all experiments in the field. The talk reviews the motivation, the current status of experiments and future programs.

  10. NDM06: 2. symposium on neutrinos and dark matter in nuclear physics

    Energy Technology Data Exchange (ETDEWEB)

    Akerib, D.; Arnold, R.; Balantekin, A.; Barabash, A.; Barnabe, H.; Baroni, S.; Baussan, E.; Bellini, F.; Bobisut, F.; Bongrand, M.; Brofferio, Ch.; Capolupo, A.; Carrara Enrico; Caurier, E.; Cermak, P.; Chardin, G.; Civitarese, O.; Couchot, F.; Kerret, H. de; Heros, C. de los; Detwiler, J.; Dracos, M.; Drexlin, G.; Efremenko, Y.; Ejiri, H.; Falchini, E.; Fatemi-Ghomi, N.; Finger, M.Ch.; Finger Miroslav, Ch.; Fiorillo, G.; Fiorini, E.; Fracasso, S.; Frekers, D.; Fushimi, K.I.; Gascon, J.; Genest, M.H.; Georgadze, A.; Giuliani, A.; Goeger-Neff, M.; Gomez-Cadenas, J.J.; Greenfield, M.; H de Jesus, J.; Hallin, A.; Hannestad, St.; Hirai, Sh.; Hoessl, J.; Ianni, A.; Ieva, M.B.; Ishihara, N.; Jullian, S.; Kaim, S.; Kajino, T.; Kayser, B.; Kochetov, O.; Kopylov, A.; Kortelainen, M.; Kroeninger, K.; Lachenmaier, T.; Lalanne, D.; Lanfranchi, J.C.; Lazauskas, R.; Lemrani, A.R.; Li, J.; Mansoulie, B.; Marquet, Ch.; Martinez, J.; Mirizzi, A.; Morfin Jorge, G.; Motz, H.; Murphy, A.; Navas, S.; Niedermeier, L.; Nishiura, H.; Nomachi, M.; Nones, C.; Ogawa, H.; Ogawa, I.; Ohsumi, H.; Palladino, V.; Paniccia, M.; Perotto, L.; Petcov, S.; Pfister, S.; Piquemal, F.; Poves, A.; Praet, Ch.; Raffelt, G.; Ramberg, E.; Rashba, T.; Regnault, N.; Ricol, J.St.; Rodejohann, W.; Rodin, V.; Ruz, J.; Sander, Ch.; Sarazin, X.; Scholberg, K.; Sigl, G.; Simkovic, F.; Sousa, A.; Stanev, T.; Strolger, L.; Suekane, F.; Thomas, J.; Titov, N.; Toivanen, J.; Torrente-Lujan, E.; Tytler, D.; Vala, L.; Vignaud, D.; Vitiello, G.; Vogel, P.; Volkov, G.; Volpe, C.; Wong, H.; Yilmazer, A

    2006-07-01

    This second symposium on neutrinos and dark matter is aimed at discussing research frontiers and perspectives on currently developing subjects. It has been organized around 6 topics: 1) double beta decays, theory and experiments (particularly: GERDA, MOON, SuperNEMO, CUORE, CANDLES, EXO, and DCBA), 2) neutrinos and nuclear physics, 3) single beta decays and nu-responses, 4) neutrino astrophysics, 5) solar neutrino review, and 6) neutrino oscillations. This document is made up of the slides of the presentations.

  11. Siphonochilus aethiopicus, a traditional remedy for the treatment of allergic asthma

    CSIR Research Space (South Africa)

    Fouché, Gerda

    2013-02-01

    Full Text Available .e-tang.org 2013 / Volume 3 / Issue 1 / e6 1 Original Article Siphonochilus aethiopicus, a traditional remedy for the treatment of allergic asthma Gerda Fouche1,*, Schalk van Rooyen1, Teresa Faleschini1,2 1Biosciences, Council for Scientific and Industrial..., herbal remedies, alternative treatment INTRODUCTION Although an overall improvement in the general health of the population was seen in the last few years, the prevalence of allergies and asthma has increased. New treatments and specifically...

  12. Kiasma - muzei s vidom na Laplandiju / Galina Balashova

    Index Scriptorium Estoniae

    Balashova, Galina

    2006-01-01

    Steven Holli projekteeritud Kiasma muuseumihoonest Helsingis. Kontseptuaalkunsti näitusest ARS 06 "Reaalsustunne" Kiasmas. Eestlastest esineb Mark Raidpere. Vene kunstnikegrupi AEC+F ja vene kunstnike Juri Vassiljevi ning Aleksandr Ponomarjovi töödest näitusel. Ka Gerda Steineri & Jörg Lenzlingeri (Šveits), Martin & Munoz'i (USA, Hispaania), videokunstnik Bill Viola (USA) töödest

  13. ARS - Helsinki - 2006 / Galina Balashova

    Index Scriptorium Estoniae

    Balashova, Galina

    2006-01-01

    Steven Holli projekteeritud Kiasma muuseumihoonest Helsingis. Kontseptuaalkunsti näitusest ARS 06 "Reaalsustunne" Kiasmas. Eestlastest esineb Mark Raidpere. Vene kunstnikegrupi AEC+F ja vene kunstnike Juri Vassiljevi ning Aleksandr Ponomarjovi töödest näitusel. Ka Gerda Steineri & Jörg Lenzlingeri (Šveits), Martin & Munoz'i (USA, Hispaania), arvutigraafik Charles Sandisoni (SB), videokunstnik Bill Viola (USA) jt. töödest

  14. Susiseb ja podiseb I-II / Mihkel Mutt

    Index Scriptorium Estoniae

    Mutt, Mihkel, 1953-

    1998-01-01

    Järg: 27. märts. 1998. a. riigi kultuuripreemiate jagamisest; Eesti Draamateatrist. Vastukajad: Kasterpalu, Margus. Marutõbine teatripäev // Postimees (1998) 30. märts, lk. 15; Aarma, Jüri. Kolm tähelepanekut susisemise ja podisemise asjus // Sõnumileht (1998) 18. apr., lk. 15; Kordemets, Gerda. Pind põues või palk silmas // Sõnumileht (1998) 18. apr., lk. 15

  15. GELATIO: a general framework for modular digital analysis of high-purity Ge detector signals

    International Nuclear Information System (INIS)

    Agostini, M; Pandola, L; Zavarise, P; Volynets, O

    2011-01-01

    GELATIO is a new software framework for advanced data analysis and digital signal processing developed for the GERDA neutrinoless double beta decay experiment. The framework is tailored to handle the full analysis flow of signals recorded by high purity Ge detectors and photo-multipliers from the veto counters. It is designed to support a multi-channel modular and flexible analysis, widely customizable by the user either via human-readable initialization files or via a graphical interface. The framework organizes the data into a multi-level structure, from the raw data up to the condensed analysis parameters, and includes tools and utilities to handle the data stream between the different levels. GELATIO is implemented in C++. It relies upon ROOT and its extension TAM, which provides compatibility with PROOF, enabling the software to run in parallel on clusters of computers or many-core machines. It was tested on different platforms and benchmarked in several GERDA-related applications. A stable version is presently available for the GERDA Collaboration and it is used to provide the reference analysis of the experiment data.

  16. Geneva University

    CERN Multimedia

    2006-01-01

    Université de Genève Ecole de physique 24 quai Ernest Ansermet 1211 Genève 4 Tél : + 41 22 379 63 83 (secrétariat) Tél : + 41 22 379 62 56 (réception) Fax: + 41 22 379 69 22 Wednesday 29th November 2006 PARTICLE PHYSICS SEMINAR at 17.00 hrs - Stückelberg Auditorium The Germanium Detector Array (GERDA) for the search of neutrinoless double beta decays of 76 Ge at LNGS line by Prof. Stefan Schoenert - Max-Planck-Institut für Kernphysik Heidelberg The Germanium Detector Array (GERDA [1]) for the search of neutrinoless double beta decays of 76Ge at LNGS will operate bare germanium diodes enriched in 76 Ge in an (optional active) cryogenic fluid shield to investigate neutrinoless double beta decay with a sensitivity of T_{1/2} > 2 x 1026~years after an exposure of 100~rm kg x rm years. In this talk, I shall introduce the relevance of neutrinoless double beta decay, the experimental concepts of GERDA, the challenges and techniques to reduce backgrounds to neutrinoless double beta decay, and summarize...

  17. Targeting the oxidative stress response system of fungi with safe, redox-potent chemosensitizing agents

    Directory of Open Access Journals (Sweden)

    Jong H. eKim

    2012-03-01

    Full Text Available The cellular antioxidation system is a target in the antifungal action of amphotericin B (AMB and itraconazole (ITZ, in filamentous fungi. The sakAΔ mutant of Aspergillus fumigatus, a mitogen-activated protein kinase (MAPK gene deletion mutant in the antioxidation system, was found to be more sensitive to AMB or ITZ than other A. fumigatus strains, a wild type and a mpkCΔ mutant (MAPK gene deletion mutant in polyalcohol sugar utilization system. The sakAΔ mutant showed no growth at 0.5 μg mL-1 of ITZ or reduced growth at 1.0 to 2.0 μg mL-1 of AMB, while the other strains exhibited robust growth. Complete fungal kill (≥ 99.9% by ITZ or AMB was achieved by much lower dosages for the sakAΔ mutant than for the other strains. SakA and MpkC appear to have overlapping roles in marshalling the oxidative stress response under treatment by an organic peroxide, tert-butyl hydroperoxide (t-BuOOH, or hydrogen peroxide (H2O2. The SakA signalling pathway was found to be responsible for fungal tolerance to AMB or ITZ toxicity. It appears msnA, an Aspergillus ortholog to Saccharomyces cerevisiae MSN2 (encoding a stress-responsive C2H2-type zinc-finger regulator and sakA and/or mpkC (upstream MAPKs are in the same stress response network under t-BuOOH-, H2O2- or AMB-triggered toxicity. Of note is that ITZ-sensitive yeast pathogens (Candida krusei and Cryptococcus neoformans were also sensitive to t-BuOOH, showing a connection between ITZ toxicity and oxidative stress response. This was shown by enhanced antifungal activity of AMB or ITZ when co-applied with redox-potent natural compounds, 2,3-dihydroxybenzaldehyde, thymol or salicylaldehyde, as chemosensitizing agents. Hence, redox compounds, which target the antioxidation system in fungi, possess a potent chemosensitizing capacity to enhance efficacy of conventional drugs inducing oxidative stress. Such chemosensitization can reduce costs and alleviate negative side effects associated with current

  18. Kreutzwaldi radadel / Tarmo Teder

    Index Scriptorium Estoniae

    Teder, Tarmo, 1958-

    2003-01-01

    Sirbi toimetuse ringreisi marsruut: Jõepere-Müüsleri-Kääpa jõgi-Kalevipoja Muuseum-Kalevipoja säng-Kreutzwaldi haud Raadi kalmistul ja Kalevipoja kuju Tartus-Dr. Fr. R. Kreutzwaldi Memoriaalmuuseum Võrus-Saadjärve. F. R. Kreuzwaldi monumendist Jõeperes, hauast Raadi kalmistul ja muuseumist Võrus (1941), taasloodud Kalevipoja kujust Tartus (E. Väli) ja Glehni pargis, Müüsleri parki kavandatavast Kilplalast, Kääpa jõest, Kalevipoja toolist, muuseumist (2002) ja sängist, F. R. Kreutzwaldile püstitatud mälestussambad (A. Adamson, Võru, 1926, A. Eller, Rakvere, 1937, J. Hirv, M. Saks, Tartu,1952, J. Raudsepp, Jõepere, 1953, E. Taniloo, M. Saks, Tallinn, 1958)

  19. Acute Toxicity Study of “Gadagi” Tea on Rats | Gadanya | Bayero ...

    African Journals Online (AJOL)

    Acute toxicity study was carried out on three most common types of “Gadagi” tea preparations, “sak'',”sada” and “magani”.. LD50 values of each type of the tea were determined. Results of phase I and phase II of the study showed no mortality was recorded in any of the experimental groups of rats in 24hours and up to four ...

  20. Eesti disain / Silvia Pärmann

    Index Scriptorium Estoniae

    Pärmann, Silvia

    2014-01-01

    Ahti Grünbergi ja Tõnis Kalve mööbliseeria Derelict. Maile Grünbergi disainitud toolid ja laud Madis. Taniel Kolpakovi kaubamärgile Rough Bloom disainitud köögimööbel. Kaubamärgi Varm Country uus kollektsioon Basic no 2. Kersti Laanmaa keraamilised teekannud Kiviaeg ja Jänes kapsas. Tiina Mangi kavandatud diivan Sik-Sak. Tõnis Vellama valgustimudel AET27

  1. Perbedaan IFRS, U.S. GAAP, Dan PSAK: Investement Property

    OpenAIRE

    L.D., Nunik

    2010-01-01

    International accounting standards convergence which has been done through adopting IFRS completely by DSAK is IAS 40 Investment Property. Based on these adopting, there will be differentiation between IFRS, U.S. GAAP and PSAK. But for PSAK valid in January 1st 2008 (SAK in July 1st 2009), there are no differentiation with IFRS because PSAK adopts IFRS completely, but between IFRS, PSAK and U.S. GAAP have differentiation. This paper will only discuss about the differentiation between IFRS, U....

  2. Praktek Akuntansi Piutang Dagang Pada PT. Aneka Gas Industri Medan

    OpenAIRE

    Syarah, Irma

    2011-01-01

    A lot of company faced difficulties in analizing, marking or classifying the receivable account. This case will cause the mistake in reporting the receivable account in the financial report in Balance Sheet. For further, this mistake will cause the different perception from the user itself. The aim of this observation is to know whether the Practical of Receivable Accounting at PT. Aneka Gas Industri Medan had been stipulated in accordance with Financial Accounting Standard (SAK) or not. Thi...

  3. Läti ja Leedu vallutavad Pärnus "Kunstisuve" / Grete Naaber

    Index Scriptorium Estoniae

    Naaber, Grete, 1942-

    2000-01-01

    17. juunil Pärnus "Kunstisuve" raames Linnagaleriis avatavast pisiplastika näitusest 3D (kuraator Terje Ojaver, esinejate hulgas Tõnu Smidt, Erik Teemägi, Reti Saks, Ivan Zubaka) ja Muuseumiaidas avatavast Jelgava, Shiauliai ja Pärnu kunstnike näitusest 3B (näitused on avatud 29. juulini); korraldaja Sirje Eelma kommentaare; samal päeval toimub Raoul Kurvitsa performance "X-file"

  4. Installation Restoration Program. Site Investigation Report. 147th Fighter Interceptor Group, Texas Air National Guard, Ellington, Field, Houston, Texas

    Science.gov (United States)

    1991-01-01

    N4.L.....-I~C1 01AME TER ...... SACKS OF TON’O 4-1At AN SCH4EDULE 40PVC SAK pTA rEINO 8LANK VLT TRAP I o GALLONS OF GVOUT USED SOTTOM WELL CAP POUNDS...and fungi on leaf surfaces and in soil. Many of these microorganisms play key roles in the decomposer food chain. Cases of lead poisoning have been

  5. Screening af kulturmiljøer

    DEFF Research Database (Denmark)

    2017-01-01

    Arkitektskolen Aarhus sætter fokus på kulturmiljøer i Danmarks yderområder. Screening af Kulturmiljøer (SAK) er et redskab til at vurdere kulturmiljøer ud fra aflæselige parametre, så kulturarvens værdier, egenskaber og udviklingspotentialer bliver synlige. Formålet er at skabe nye muligheder og...

  6. Etude des principales causes de cecite dans le Sud Benin: cas de la ...

    African Journals Online (AJOL)

    But: Le but de ce travail est d'étudier les principales causes de cécité chez les sujets de plus de 50 ans dans la commune de Sakété du Sud-Bénin. Méthode : Notre enquête transversale dans la population pendant 1 de 50 ans et plus a été effectuée pendant 1 mois. Nous avons examiné 846 personnes ayant ...

  7. Mengukur Tingkat Kesesuaian antara Standar Akuntansi Keuangan dengan International Financial Reporting Standards per 1 Januari 2008

    Directory of Open Access Journals (Sweden)

    Rosinta Ria Panggabean

    2010-05-01

    Full Text Available International accounting topic was rare to adress between accounting practices, especially International Accounting Standard. It occured due to the restrictive source and difficulty in finding the source. However, recently the standard has been an addressed issue since Indonesia Chartered of Accountant (IAI plans to comply the Indonesia Accounting Standard (SAK with the International Financialreporting(IFRSon1stJanuary2012.The purpose of the research is to measure the compliance of the (SAK per 1st January 2008 with the IFRS per 1st January 2008 and attain the association between those two standards. Hence, the difference between the two standards and the neccessary steps to be taken for complying can be obtained. The methodology will be used in the paper are Jaccard’s Coefficients, Spearman’s Correlation Coefficient,Euclidean Distances.The sample for the paper will be 43 accounting issues adressed on both standards that have been chosen and investigated. The paper concludes that there are significant equalities (75% between SAK per 1st January 2008 and IFRS 1st January 2008. (using Jaccard’s Coefficients. Due to several problems that have been found in the research, the author wish that the further researchers could widen the research’s samples, so the result will be more accurate and comprehensive. 

  8. Biological and advanced treatment of sulfate pulp bleaching effluents

    International Nuclear Information System (INIS)

    Çeçen, F.; Urban, W.; Haberl, R.

    1992-01-01

    Spent bleaching effluents (from chlorination (C) and extraction (E) stages) of a sulfate pulp mill were subjected to bench-scale biological and advanced treatment. Although > 90 % of the influent BOD 5 could be removed in an activated sludge process, the effluent still contained high amounts of resistant substances. The maximum COD removal was about 50 %; the removal rates achieved in the parameters TOC, DOC, AOX, SAK (254 nm) were even lower. The biological treatment led to an increase in color (436 nm) up to 40 %. The biologically pretreated effluent was further treated by ozone or ozone/irradiation. The DOC, COD, color (436 nm), SAK (254 nm) and AOX removal rates amounted to 61 %, 81 %, 98 %, 92 % and 92 %, respectively. These methods led simultaneously to an increase in biological biodegradability as reflected by an increase in BOD 5 . A comparison of the results obtained for raw and biologically pretreated wastewaters showed that biodegradable substances should first be removed from the wastewater since otherwise the effectiveness of these methods decreased. The coagulation/flocculation of biologically pretreated effluent showed that FeCl3 was the most effective coagulant and that removal rates > 90 % could be achieved. The treatment with various powder activated carbons showed that a dosage of 10 g/l was required to achieve elimination rates > 90 % in the parameters DOC, COD, color (436 nm) and SAK (254 nm). Adsorption isotherms were developed for every activated carbon and adsorption constants were calculated. (author)

  9. Genome comparisons of two Taiwanese community-associated methicillin-resistant Staphylococcus aureus ST59 clones support the multi-origin theory of CA-MRSA.

    Science.gov (United States)

    Feng, Ye; Chen, Hsiu-Ling; Chen, Chih-Jung; Chen, Chyi-Liang; Chiu, Cheng-Hsun

    2017-10-01

    Sequence type (ST) 59 is an epidemic lineage of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Asia. Two ST59 clones are prevalent in Taiwan: the Taiwan clone (TW) causes severe infections, whereas the Asian-Pacific clone (AP) is usually commensal. In this study, we sequenced the genome and transcriptome of the representative strains of these two clones and found their differences to focus on three mobile genetic elements: TW carries SCCmec Type V T , Panton-Valentine leucocidin (PVL)-encoding prophage ΦSa2, whereas AP carries SCCmec Type IV and staphylokinase (SAK)-encoding prophage ΦSa3. The anti-virulent role of SAK was confirmed using murine skin and bloodstream infection models. ΦSa3 usually integrates into the hlb gene, but in AP was found to be integrated at the genomic island νSaβ. The mutation of the attB site "TGTATCCAAACTGG" to "TGTATCCGAATTGG" led to a failure in the integration of ΦSa3 in hlb, prompting atypical integration at other sites. The sak gene possessed remarkably different patterns of distribution among the different STs of S. aureus. We conclude that the atypical integration of ΦSa3 may help S. aureus adapt to the human host habitat and that the subsequent loss of ΦSa3 contributes toward the development of a virulent CA-MRSA lineage for wider horizontal transmission. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. The Use of Pocket Electronic Dictionaries by Thai University Students

    Directory of Open Access Journals (Sweden)

    Atipat Boonmoh

    2011-10-01

    Full Text Available

    ABSTRACT: This article reports on a small-scale study of Thai-speaking learners using pocket electronic dictionaries (PEDs to read an English news article. It investigates how the subjects use their PEDs for reading comprehension. Thirty-nine undergraduate students completed a questionnaire survey. Of these, four were chosen to participate in the experiment. Observations and interviews were utilized to ascertain how the subjects used their PEDs. The findings showed superficial and partial reading of the dictionary entries. It also revealed several factors that may hinder dictionary look-up success. On the basis of this research, guidelines for buying PEDs and for teaching PED skills are proposed.

    OPSOMMING: Die gebruik van sak- elektroniese woordeboeke deur Thaise universiteitstudente. Hierdie artikel doen verslag van 'n kleinskaalse studie van Thaisprekende aanleerders wat sak- elektroniese woordeboeke (SEW's gebruik om 'n Engelse nuusartikel te lees. Dit ondersoek hoe die proefpersone hul SAW's gebruik vir leesbegrip. Nege-en-dertig voorgraadse studente het 'n vraelysopname voltooi. Uit hulle is vier gekies om aan die eksperiment deel te neem. Waarnemings en onderhoude is aangewend om te bepaal hoe die proefpersone hul SEW's gebruik het. Die bevindings het oppervlakkige en gedeeltelike lees van die woordeboekinskrywings getoon. Dit het ook verskeie faktore uitgewys wat woordeboekopsoeksukses mag belemmer. Op grond van hierdie navorsing word riglyne vir die koop van SEW's en vir die onderrig van SEWvaardighede voorgestel.

    Sleutelwoorde: WOORDEBOEKGEBRUIK, SAK- ELEKTRONIESE WOORDEBOEK, WOORDEBOEKRAADPLEGING, EENTALIGE WOORDEBOEK, TWEETALIGE WOORDEBOEK

  11. Pulse shapes and surface effects in segmented germanium detectors

    Energy Technology Data Exchange (ETDEWEB)

    Lenz, Daniel

    2010-03-24

    It is well established that at least two neutrinos are massive. The absolute neutrino mass scale and the neutrino hierarchy are still unknown. In addition, it is not known whether the neutrino is a Dirac or a Majorana particle. The GERmanium Detector Array (GERDA) will be used to search for neutrinoless double beta decay of {sup 76}Ge. The discovery of this decay could help to answer the open questions. In the GERDA experiment, germanium detectors enriched in the isotope {sup 76}Ge are used as source and detector at the same time. The experiment is planned in two phases. In the first, phase existing detectors are deployed. In the second phase, additional detectors will be added. These detectors can be segmented. A low background index around the Q value of the decay is important to maximize the sensitivity of the experiment. This can be achieved through anti-coincidences between segments and through pulse shape analysis. The background index due to radioactive decays in the detector strings and the detectors themselves was estimated, using Monte Carlo simulations for a nominal GERDA Phase II array with 18-fold segmented germanium detectors. A pulse shape simulation package was developed for segmented high-purity germanium detectors. The pulse shape simulation was validated with data taken with an 19-fold segmented high-purity germanium detector. The main part of the detector is 18-fold segmented, 6-fold in the azimuthal angle and 3-fold in the height. A 19th segment of 5mm thickness was created on the top surface of the detector. The detector was characterized and events with energy deposited in the top segment were studied in detail. It was found that the metalization close to the end of the detector is very important with respect to the length of the of the pulses observed. In addition indications for n-type and p-type surface channels were found. (orig.)

  12. Phenomenology of experiential sharing

    DEFF Research Database (Denmark)

    León, Felipe; Zahavi, Dan

    2016-01-01

    The chapter explores the topic of experiential sharing by drawing on the early contributions of the phenomenologists Alfred Schutz and Gerda Walther. It is argued that both Schutz and Walther support, from complementary perspectives, an approach to experiential sharing that has tended to be overl...... to the sharing of experiences describes the latter as a pre-reflective interlocking of individual streams of experiences, arising from a reciprocal Thou-orientation, Walther provides a textured account of different types of sharing and correlated forms of communities....

  13. La ciencia del cosmos, la ciencia en el cosmos : 2013-2014 : ciclo de conferencias de astrofisica y cosmologia

    CERN Document Server

    Science of the Cosmos, Science in the Cosmos : 2013-2014 : series of lectures on astrophysics and cosmology

    2014-01-01

    Welcome to "Science of the Cosmos, Sciences in the Cosmos", the series of lectures that the BBVA Foundation has been offering, live and on DVD, since March 2011. Lecture 1 : Let there be light : finding the earliest galaxies / Richard Ellis ; lecture 2 : The origin of the galaxies / Simon White ; lecture 3 : Astrobiology : the quest for the conditions of life in the Universe / Gerda Horneck ; lecture 4 : The long-term stability of planetary systems / Scott Tremaine ; lecture 5 : Asteroseismology : the study of starquakes and its impact on astrophysics / Conny Aerts ; lecture 6 : From Mars to multiverse / Martin Rees

  14. A eutonia e o trabalho do ator: experimentos

    OpenAIRE

    Fernanda Moretti Pereira de Faria

    2010-01-01

    A proposta da presente pesquisa é a prática corporal da Eutonia como ferramenta de suporte para o trabalho do ator, exemplificado pelo Sistema de K. Stanislavski. Sua leitura permite a assimilação dos conceitos teóricos da Eutonia criada por Gerda Alexander e a compreensão dos resultados práticos, descritos através de um experimento com um grupo de atores em formação. O estudo realizado em uma etapa literária e outra vivencial demonstra as possíveis conexões entre Alexander e Stanislavski. De...

  15. La Eutonía-Sus Principios

    OpenAIRE

    Rovella, Adriana

    2008-01-01

    El presente trabajo pretende dar cuenta de la Eutonía como práctica corporal dando cuenta de sus objetivos y principios La Eutonía fue creada por Gerda Alexander.El término, del griego, Eu: bueno, óptimo-Tonus: tensión; expresa la idea de una tonicidad armoniosamente equilibrada en adaptación constante al estado o actividad del momento. Es una disciplina basada en la experiencia del propio cuerpo, que conduce a la persona hacia una toma de conciencia de si misma y propone un aprendizaje para ...

  16. En la construcción del espacio interno desde la Eutonia - Escenas

    OpenAIRE

    Rovella, Adriana

    2011-01-01

    El presente trabajo contará sobre la Eutonía. Creada a mediados de 1900 por Gerda Alexander quien para el desarrollo de la misma supo integrar sus formaciones previas de música, danza, pedagogía con nuevas búsquedas, algunas surgidas durante períodos de tiempo en que guardó reposo por enfermedades. Propuso a la Eutonía como una pedagogía desde la que se alienta a aprendizajes a través del cuerpo, la atención y la concentración, a percibirse, reconocerse, moverse con economía, flexibilidad, fu...

  17. Development of segmented germanium detectors for neutrinoless double beta decay experiments

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Jing

    2009-06-09

    The results from neutrino oscillation experiments indicate that at least two neutrinos have mass. However, the value of the masses and whether neutrinos and anti-neutrinos are identical, i.e., Majorana particles, remain unknown. Neutrinoless double beta decay experiments can help to improve our understanding in both cases and are the only method currently possible to tackle the second question. The GERmanium Detector Array (GERDA) experiment, which will search for the neutrinoless double beta decay of {sup 76}Ge, is currently under construction in Hall A of the INFN Gran Sasso National Laboratory (LNGS), Italy. In order to achieve an extremely low background level, segmented germanium detectors are considered to be operated directly in liquid argon which serves simultaneously as cooling and shielding medium. Several test cryostats were built at the Max-Planck-Institut fuer Physik in Muenchen to operate segmented germanium detectors both in vacuum and submerged in cryogenic liquid. The performance and the background discrimination power of segmented germanium detectors were studied in detail. It was proven for the first time that segmented germanium detectors can be operated stably over long periods submerged in a cryogenic liquid. It was confirmed that the segmentation scheme employed does well in the identification of photon induced background and demonstrated for the first time that also neutron interactions can be identified. The C++ Monte Carlo framework, MaGe (Majorana-GERDA), is a joint development of the Majorana and GERDA collaborations. It is based on GEANT4, but tailored especially to simulate the response of ultra-low background detectors to ionizing radiation. The predictions of the simulation were veri ed to be accurate for a wide range of conditions. Some shortcomings were found and corrected. Pulse shape analysis is complementary to segmentation in identifying background events. Its efficiency can only be correctly determined using reliable pulse

  18. Selgusid parimad noored luuletajad / Triin Kandi, Minni Saapar

    Index Scriptorium Estoniae

    Kandi, Triin

    2008-01-01

    Kuressaare noorte huvikeskuse korraldatud luulekonkursist "Noored poeedid 2008". Kuni 11aastaste hulgas sai I koha Karin Kreek, II koha Teele Tilts ja III koha Eerik Poopuu. Eripreemia sai Mikk Kärner. 12-15aastaste hulgas sai I koha Gerda-Liis Palmiste, II koha Kattre Adramees ja III koha Monika Turba. 16-aastaste ja vanemate vanuserühmas sai I koha Kaisa Kuusk, II koha Robert Vahter ja III koha Mona-Theresa Võlma. Eripreemia sai Heli Arnus. Artikkel sisaldab ka Kaisa Kuuse võiduluuletust

  19. METHANE HYDRATE PRODUCTION FROM ALASKAN PERMAFROST

    Energy Technology Data Exchange (ETDEWEB)

    Richard Sigal; Kent Newsham; Thomas Williams; Barry Freifeld; Timothy Kneafsey; Carl Sondergeld; Shandra Rai; Jonathan Kwan; Stephen Kirby; Robert Kleinberg; Doug Griffin

    2005-02-01

    Natural-gas hydrates have been encountered beneath the permafrost and considered a nuisance by the oil and gas industry for years. Engineers working in Russia, Canada and the USA have documented numerous drilling problems, including kicks and uncontrolled gas releases, in arctic regions. Information has been generated in laboratory studies pertaining to the extent, volume, chemistry and phase behavior of gas hydrates. Scientists studying hydrate potential agree that the potential is great--on the North Slope of Alaska alone, it has been estimated at 590 TCF. However, little information has been obtained on physical samples taken from actual rock containing hydrates. The work scope drilled and cored a well The Hot Ice No. 1 on Anadarko leases beginning in FY 2003 and completed in 2004. An on-site core analysis laboratory was built and utilized for determining the physical characteristics of the hydrates and surrounding rock. The well was drilled from a new Anadarko Arctic Platform that has a minimal footprint and environmental impact. The final efforts of the project are to correlate geology, geophysics, logs, and drilling and production data and provide this information to scientists developing reservoir models. No gas hydrates were encountered in this well; however, a wealth of information was generated and is contained in this report. The Hot Ice No. 1 well was drilled from the surface to a measured depth of 2300 ft. There was almost 100% core recovery from the bottom of surface casing at 107 ft to total depth. Based on the best estimate of the bottom of the methane hydrate stability zone (which used new data obtained from Hot Ice No. 1 and new analysis of data from adjacent wells), core was recovered over its complete range. Approximately 580 ft of porous, mostly frozen, sandstone and 155 of conglomerate were recovered in the Ugnu Formation and approximately 215 ft of porous sandstone were recovered in the West Sak Formation. There were gas shows in the bottom

  20. Expression of recombinant staphylokinase, a fibrin-specific plasminogen activator of bacterial origin, in potato (Solanum tuberosum L.) plants.

    Science.gov (United States)

    Gerszberg, Aneta; Wiktorek-Smagur, Aneta; Hnatuszko-Konka, Katarzyna; Łuchniak, Piotr; Kononowicz, Andrzej K

    2012-03-01

    One of the most dynamically developing sectors of green biotechnology is molecular farming using transgenic plants as natural bioreactors for the large scale production of recombinant proteins with biopharmaceutical and therapeutic values. Such properties are characteristic of certain proteins of bacterial origin, including staphylokinase. For many years, work has been carried out on the use of this protein in thrombolytic therapy. In this study, transgenic Solanum tuberosum plants expressing a CaMV::sak-mgpf-gusA gene fusion, were obtained. AGL1 A. tumefaciens strain was used in the process of transformation. The presence of the staphylokinase gene was confirmed by PCR in 22.5% of the investigated plants. The expression of the fusion transgene was detected using the β-glucuronidase activity assay in 32 putative transgenic plants. Furthermore, on the basis of the GUS histochemical reaction, the transgene expression pattern had a strong, constitutive character in seven of the transformants. The polyacrylamide gel electrophoresis of a protein extract from the SAK/PCR-positive plants, revealed the presence of a119 kDa protein that corresponds to that of the fusion protein SAK-mGFP-GUSA. Western blot analysis, using an antibody against staphylokinase, showed the presence of the staphylokinase domain in the 119 kDa protein in six analyzed transformants. However, the enzymatic test revealed amidolytic activity characteristic of staphylokinase in the protein extract of only one plant. This is the first report on a Solanum tuberosum plant producing a recombinant staphylokinase protein, a plasminogen activator of bacterial origin.

  1. The innate immune modulators staphylococcal complement inhibitor and chemotaxis inhibitory protein of Staphylococcus aureus are located on beta-hemolysin-converting bacteriophages.

    Science.gov (United States)

    van Wamel, Willem J B; Rooijakkers, Suzan H M; Ruyken, Maartje; van Kessel, Kok P M; van Strijp, Jos A G

    2006-02-01

    Two newly discovered immune modulators, chemotaxis inhibitory protein of Staphylococcus aureus (CHIPS) and staphylococcal complement inhibitor (SCIN), cluster on the conserved 3' end of beta-hemolysin (hlb)-converting bacteriophages (betaC-phis). Since these betaC-phis also carry the genes for the immune evasion molecules staphylokinase (sak) and enterotoxin A (sea), this 8-kb region at the 3' end of betaC-phi represents an innate immune evasion cluster (IEC). By PCR and Southern analyses of 85 clinical Staphylococcus aureus strains and 5 classical laboratory strains, we show that 90% of S. aureus strains carry a betaC-phi with an IEC. Seven IEC variants were discovered, carrying different combinations of chp, sak, or sea (or sep), always in the same 5'-to-3' orientation and on the 3' end of a betaC-phi. From most IEC variants we could isolate active bacteriophages by mitomycin C treatment, of which lysogens were generated in S. aureus R5 (broad phage host). All IEC-carrying bacteriophages integrated into hlb, as was measured by Southern blotting of R5 lysogens. Large quantities of the different bacteriophages were obtained by mitomycin C treatment of the lysogens, and bacteriophages were collected and used to reinfect all lysogenic R5 strains. In total, five lytic families were found. Furthermore, phage DNA was isolated and digested with EcoR1, revealing that one IEC variant can be found on different betaI-phis. In conclusion, the four human-specific innate immune modulators SCIN, CHIPS, SAK, and SEA form an IEC that is easily transferred among S. aureus strains by a diverse group of beta-hemolysin-converting bacteriophages.

  2. Eestlased graafikanäitustel / Benjamin Vasserman

    Index Scriptorium Estoniae

    Vasserman, Benjamin

    1999-01-01

    IV Kochi graafikatriennaalil Jaapanis 13. III-18. IV osales Eestist Benjamin Vasserman tööga "Vaheldus I". Peapreemia: Eduardo Roca Zalazar. XIV rahvusvahelisel graafikanäitusel "Premio Internationale Biella per I'Incisione" Itaalias 23. IV-23. V osalesid Eestist Peeter Allik, Reti Saks, Benjamin Vasserman. Näituse nimeline preemia: Seung Yeon Kim. 26. VIII avati Fredrikstadis 12. Norra rahvusvaheline graafikatriennaal. 5. nov. avatakse X Varna graafikabiennaal Bulgaarias, 15. XII ئ III Egiptuse graafikatriennaal Gizas. "International Print Triennial Cracow 2000" näitustest

  3. SYRUP AMKESOL REDUCES THE LEVEL OF PRIMARY AND SECONDARY PRODUCTS OF LIPID PEROXIDATION AND TOXIC METABOLITES OF NITRIC OXIDE IN BLOOD SERUM OF IMMATURE RATS WITH BRONCHIOLITIS

    Directory of Open Access Journals (Sweden)

    Storozhenko KV

    2017-03-01

    Full Text Available Aim of this study was to determine the pharmacological effect of syrup Amkesol evaluating the blood serum levels of primary and secondary products of lipid peroxidation, activity of AO enzymes and final rates of NO metabolites in immature rats of different ages with experimental model of bronchoalveolitis. Materials and Methods: The study was carried out on 90 WAG immature rats of ages 1, 2 and 3 menthes, that correlates by morpho-functional features to 4, 10 and 14 years of human age respectively, on a model of bronchoalveolitis. Experimental animals in each age series were randomly divided into 5 groups (n = 6: intact (healthy, 2 groups of control (untreated with bronchoalveolitis 7 and 14 days, and two groups with bronchoalveolatis that received S-AKS daily during 7 and 14 days. The pathological process implemented by inhalation of irritant (Sephadex A-25 Pharmacia, Sweden (5 mg/kg. In the blood serum samples activity of CAT, SOD, content of DC, TBARS, total NO, nitrates and nitrites were determined. Probability of the results was evaluated by using GraphPad Prism Software. The critical level of significance was taken equal to 0.05. Results. The use of S-AKS on the 7th day in the group of 1- and 3-month-old rats significantly exceeded activity of CAT compared to the control group of animals of corresponded age. The SOD activity in group of 2-month-old animals was restored to intact level, the activity of CAT exceeded the baseline level and amounted to 129% (P≤0,05. The concentration of DC in 1-month-old rats was lower by 45.3% in 2 monthly - by 12.5% than in the control group, in the group of 3 month-old animals - restored to normal (P≤0,05. The level of NO metabolites was significantly decreased compared to the corresponding control group in all age series (P≤0,05. After 14 days of treatment with S-AKS in all age group of animals observed restore the contents of primary and secondary products of lipid peroxidation compared to the

  4. Complex function theory

    CERN Document Server

    Sarason, Donald

    2007-01-01

    Complex Function Theory is a concise and rigorous introduction to the theory of functions of a complex variable. Written in a classical style, it is in the spirit of the books by Ahlfors and by Saks and Zygmund. Being designed for a one-semester course, it is much shorter than many of the standard texts. Sarason covers the basic material through Cauchy's theorem and applications, plus the Riemann mapping theorem. It is suitable for either an introductory graduate course or an undergraduate course for students with adequate preparation. The first edition was published with the title Notes on Co

  5. Substituted dihydronaphthalenes as efflux pump inhibitors of Staphylococcus aureus

    DEFF Research Database (Denmark)

    Thota, Niranjan; Reddy, Mallepally V; Kumar, Ashwani

    2010-01-01

    A new series of 3-(substituted-3,4-dihydronaphthyl)-2-propenoic acid amides has been prepared through convergent synthetic strategies and tested in combination with ciprofloxacin against NorA overexpressing Staphylococcus aureus 1199B as test strain for potentiating of the drug activity. Out of 24...... compounds evaluated, 12 compounds potentiated the activity of ciprofloxacin and resulted in 2-16 fold reduction in the MIC (4-0.5 microg/mL) of the drug. The failure of these efflux pump inhibitors (EPIs) to potentiate the activity of ciprofloxacin when tested against NorA knock out S. aureus SA-K1758...

  6. Flavour-active wine yeasts

    OpenAIRE

    Cordente, Antonio G.; Curtin, Christopher D.; Varela, Cristian; Pretorius, Isak S.

    2012-01-01

    The flavour of fermented beverages such as beer, cider, saké and wine owe much to the primary fermentation yeast used in their production, Saccharomyces cerevisiae. Where once the role of yeast in fermented beverage flavour was thought to be limited to a small number of volatile esters and higher alcohols, the discovery that wine yeast release highly potent sulfur compounds from non-volatile precursors found in grapes has driven researchers to look more closely at how choice of yeast can infl...

  7. Savisaare erakonda toetab veerand kõigist valijatest / Tuuli Koch

    Index Scriptorium Estoniae

    Koch, Tuuli

    2006-01-01

    Ilmunud ka: Postimees : na russkom jazõke ja Pärnu Postimees 9. märts lk. 2,5. Veebruaris korraldas TSN Emor Eesti erakondade reitingu uurimuse, mille kohaselt Keskerakonna toetajaid oli 25%, Reformierakonna toetajaid 13% ning ülejäänud erakonnad said 7 ja vähem protsenti toetushäältest. Graafik: Populaarseim partei on Keskerakond. Diagrammid: Toetus Keskerakonnale (%). Lisa: Parteide toetus. Arvamust avaldavad: Katrin Saks, Margus Tsahkna, Ott Lumi, Kadri Must, Agu Uudelepp ja Kristen Michal. Vt. samas: Protsendi paranoia

  8. Kolga-Jaani kihelkond ja Vabaduse Risti vennad / Jaak Pihlak

    Index Scriptorium Estoniae

    Pihlak, Jaak

    2003-01-01

    Viljandimaaga seotud järgmiste Vabadusristi kavaleride elulood: Jakob Aaren, Joosep Aas, Anton Anni, Jakob Ant, Peeter-Viktor Kanasaar, Julius Kasper, Martin-Alexander Kepmann, Georg Kesküla, Peeter Kolts, Joosep Korts, August Kull, Georg Kütt, Georg Liiv, Eduard Meijel, August Moks, Theodor Mölter, Arnold-Rudolf Orik, August Paia, Aleksander Pajur, Oskar Parvet, Tõnis Pedak, August Pent, Heinrich Puidak, Jaan Päsna, Elmar Rei, Ernst Saar, Jüri Saks, August Schönberg, August-Johannes Teose, Hans Timpson, Anton Unt, Julian Vares, Paul Vares

  9. METHANE HYDRATE PRODUCTION FROM ALASKAN PERMAFROST

    Energy Technology Data Exchange (ETDEWEB)

    Donn McGuire; Steve Runyon; Richard Sigal; Bill Liddell; Thomas Williams; George Moridis

    2005-02-01

    Natural-gas hydrates have been encountered beneath the permafrost and considered a nuisance by the oil and gas industry for years. Engineers working in Russia, Canada and the USA have documented numerous drilling problems, including kicks and uncontrolled gas releases, in arctic regions. Information has been generated in laboratory studies pertaining to the extent, volume, chemistry and phase behavior of gas hydrates. Scientists studying hydrate potential agree that the potential is great--on the North Slope of Alaska alone, it has been estimated at 590 TCF. However, little information has been obtained on physical samples taken from actual rock containing hydrates. This gas-hydrate project is in the final stages of a cost-shared partnership between Maurer Technology, Noble Corporation, Anadarko Petroleum, and the U.S. Department of Energy's Methane Hydrate R&D program. The purpose of the project is to build on previous and ongoing R&D in the area of onshore hydrate deposition to identify, quantify and predict production potential for hydrates located on the North Slope of Alaska. Hot Ice No. 1 was planned to test the Ugnu and West Sak sequences for gas hydrates and a concomitant free gas accumulation on Anadarko's 100% working interest acreage in section 30 of Township 9N, Range 8E of the Harrison Bay quadrangle of the North Slope of Alaska. The Ugnu and West Sak intervals are favorably positioned in the hydrate-stability zone over an area extending from Anadarko's acreage westward to the vicinity of the aforementioned gas-hydrate occurrences. This suggests that a large, north-to-south trending gas-hydrate accumulation may exist in that area. The presence of gas shows in the Ugnu and West Sak reservoirs in wells situated eastward and down dip of the Hot Ice location indicate that a free-gas accumulation may be trapped by gas hydrates. The Hot Ice No. 1 well was designed to core from the surface to the base of the West Sak interval using the

  10. Disease: H00056 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00056 Alzheimer's disease (AD) Alzheimer's disease (AD) is a chronic disorder tha...sak JM, Holtzman DM ... TITLE ... The role of apolipoprotein E in Alzheimer's disease. ... JOURNAL ... Neuron 63:2...87-303 (2009) DOI:10.1016/j.neuron.2009.06.026 ... PMID:18802446 ... AUTHORS ... Bertram L, Tanzi RE ... TITLE ... Thirty years of Alzheimer...Cacabelos R ... TITLE ... Pharmacogenomics in Alzheimer's disease. ... JOURNAL ... Methods Mol Biol 448:213-357 (2...008) DOI:10.1007/978-1-59745-205-2_10 ... PMID:17082447 ... AUTHORS ... Goedert M, Spillantini MG ... TITLE ... A century of Alzheimer

  11. Characterization of oil and gas reservoir heterogeneity

    Energy Technology Data Exchange (ETDEWEB)

    1991-01-01

    The objective of the cooperative research program is to characterize Alaskan reservoirs in terms of their reserves, physical and chemical properties, geologic configuration and structure, and the development potential. The tasks completed during this period include: (1) geologic reservoir description of Endicott Field; (2) petrographic characterization of core samples taken from selected stratigraphic horizons of the West Sak and Ugnu (Brookian) wells; (3) development of a polydispersed thermodynamic model for predicting asphaltene equilibria and asphaltene precipitation from crude oil-solvent mixtures, and (4) preliminary geologic description of the Milne Point Unit.

  12. Characterization of oil and gas reservoir heterogeneity. Annual report, November 1, 1990--October 31, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-12-31

    The objective of the cooperative research program is to characterize Alaskan reservoirs in terms of their reserves, physical and chemical properties, geologic configuration and structure, and the development potential. The tasks completed during this period include: (1) geologic reservoir description of Endicott Field; (2) petrographic characterization of core samples taken from selected stratigraphic horizons of the West Sak and Ugnu (Brookian) wells; (3) development of a polydispersed thermodynamic model for predicting asphaltene equilibria and asphaltene precipitation from crude oil-solvent mixtures, and (4) preliminary geologic description of the Milne Point Unit.

  13. Optimization of waste water discharge and waste water cleaning on the basis of measurements of the organic pollutant load; Optimierung von Abwasserableitung und Abwasserreinigung durch Messung der organischen Abwasserbelastung

    Energy Technology Data Exchange (ETDEWEB)

    Haeck, M. [Dr. Bruno Lange GmbH Berlin, Duesseldorf (Germany)

    1999-07-01

    The spectral absorption coefficient (SAC) is a sum parameter for describing the organic pollutant load of waste water. It is based on a purely physical measuring technique and can be monitored continuously and directly in the medium by means of the described UV process probe. From this arise numerous opportunities for optimizing waste water discharge and cleaning. (orig.) [German] Der spektrale Absorptionskoeffizient (SAK) ist ein Summenparameter zur Beschreibung der organischen Abwasserbelastung. Er basiert auf einem rein physikalischen Messverfahren und kann mit der hier vorgestellten UV-Prozess-Sonde kontinuierlich und direkt im Medium erfasst werden. Daraus ergeben sich zahlreiche Moeglichkeiten zur Optimierung von Abwasserableitung und -reinigung. (orig.)

  14. Prior-Free Multi-Unit Auctions with Ordered Bidders

    Science.gov (United States)

    2014-05-01

    analysis framework based on revenue benchmarks [6, 20]; see also the survey by Hartline and Karlin [15].1 The idea is to define a real-valued function on...Goldberg, J. D. Hartline, A. Karlin , M. Saks, and A. Wright. Competitive auctions. Games and Economic Behavior, 55(2):242–269, 2006. [12] A. V...design. Book in preparation, 2012. [15] J. D. Hartline and A. Karlin . Profit maximization in mechanism design. In N. Nisan, T. Rough- garden, É. Tardos

  15. Scientific Creativity and High Ability: Gender and academic level differences

    Directory of Open Access Journals (Sweden)

    Fernando Javier ESPARZA MOLINA

    2015-10-01

    Full Text Available  The purpose of this study was to investigate the influence of gender and educational level on scientific creativity among gifted/talented students. A cohort of creatividad científica y alta habilidad: diferencias de género y nivel educativo 78 secondary school students from 12 to 16 years old participated in this research. The scientific creativity was measured using the Creative Scientific Ability Test (Sak & Ayas, 2011 designed for secondary school students from 11 to 14 years old. Its theoretical framework sets up the measurement of a three dimensional structure: general creative abilities (fluency, flexibility and creativity, scientific creative abilities (hypothesis generation, hypothesis testing and evidence evaluation and scientific knowledge. This test has the right adequate psychometric properties with a Cronbach’s alpha coefficient of 0.848 (Sak & Ayas, 2013. Results indicated that male students scored significantly higher in a task named Interaction Graph which measures hypothesis generation in interdisciplinary science. The analysis also showed that students involved in upper education levels scores significantly higher in general fluency and in the task called The Food Chain which measures evidence evaluation in the area of ecology.

  16. Evidence for Domesticated and Wild Populations of Saccharomyces cerevisiae.

    Directory of Open Access Journals (Sweden)

    2005-07-01

    Full Text Available Saccharomyces cerevisiae is predominantly found in association with human activities, particularly the production of alcoholic beverages. S. paradoxus, the closest known relative of S. cerevisiae, is commonly found on exudates and bark of deciduous trees and in associated soils. This has lead to the idea that S. cerevisiae is a domesticated species, specialized for the fermentation of alcoholic beverages, and isolates of S. cerevisiae from other sources simply represent migrants from these fermentations. We have surveyed DNA sequence diversity at five loci in 81 strains of S. cerevisiae that were isolated from a variety of human and natural fermentations as well as sources unrelated to alcoholic beverage production, such as tree exudates and immunocompromised patients. Diversity within vineyard strains and within saké strains is low, consistent with their status as domesticated stocks. The oldest lineages and the majority of variation are found in strains from sources unrelated to wine production. We propose a model whereby two specialized breeds of S. cerevisiae have been created, one for the production of grape wine and one for the production of saké wine. We estimate that these two breeds have remained isolated from one another for thousands of years, consistent with the earliest archeological evidence for winemaking. We conclude that although there are clearly strains of S. cerevisiae specialized for the production of alcoholic beverages, these have been derived from natural populations unassociated with alcoholic beverage production, rather than the opposite.

  17. Characterization of oil and gas reservoir heterogeneity; Final report, November 1, 1989--June 30, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, G.D.

    1993-09-01

    The Alaskan North Slope comprises one of the Nation`s and the world`s most prolific oil province. Original oil in place (OOIP) is estimated at nearly 70 BBL (Kamath and Sharma, 1986). Generalized reservoir descriptions have been completed by the University of Alaska`s Petroleum Development Laboratory over North Slope`s major fields. These fields include West Sak (20 BBL OOIP), Ugnu (15 BBL OOIP), Prudhoe Bay (23 BBL OOIP), Kuparuk (5.5 BBL OOIP), Milne Point (3 BBL OOIP), and Endicott (1 BBL OOIP). Reservoir description has included the acquisition of open hole log data from the Alaska Oil and Gas Conservation Commission (AOGCC), computerized well log analysis using state-of-the-art computers, and integration of geologic and logging data. The studies pertaining to fluid characterization described in this report include: experimental study of asphaltene precipitation for enriched gases, CO{sup 2} and West Sak crude system, modeling of asphaltene equilibria including homogeneous as well as polydispersed thermodynamic models, effect of asphaltene deposition on rock-fluid properties, fluid properties of some Alaskan north slope reservoirs. Finally, the last chapter summarizes the reservoir heterogeneity classification system for TORIS and TORIS database.

  18. KELUARGA NIRKEKERASAN SEBAGAI PRASYARAT KELUARGA SAKÎNAH

    Directory of Open Access Journals (Sweden)

    Moh. Makmun

    2015-09-01

    Full Text Available The article tries to redefine the meaning of sakînah family by emphasizing the importance of understanding the essence of marriage and domestic violence, which leads to criminal action, for spouse. Marriage is a social contract and agreement between a man and a woman, which aims at legalizing sexual interaction, making familial relationship through marriage, ensuring one’s descendant, making a family, and living life together. Criminal action within marital relationship is any action committed by each spouse over another that violates laws, any action that harms his/her spouse physically, physiologically and economically, and/or a spouse who ignores his/her responsibility over another and over his/her children in the domestic sphere. Sakînah family is a family which build on the basis of faith and piety upon God, a family whose breadwinner is able to fulfill the needs of family members based on his ability, a family which lives harmoniously and peacefully, a family which possesses ability and capability to overcome any conflicts among its members, a family with no violence and domestic crime, and a family whose members play their role respectively.

  19. Desain Kapal 3-in-1 Penumpang-Barang-Container Rute Surabaya – Lombok

    Directory of Open Access Journals (Sweden)

    I Gede Hadi Saputra

    2017-01-01

    Full Text Available Dalam proses pembangunan ekonomi Indonesia, berbagai upaya telah dilakukan oleh pemerintah antara lain program Masterplan Percepatan dan Perluasan Pembangunan Ekonomi Indonesia (MP3EI dan juga Program Tol Laut. Program-program tersebut diambil oleh pemerintah agar terjadi pemerataan pembangunan ekonomi di setiap daerah demi meningkatkan kondisi ekonomi Indonesia. Dalam mengaplikasikan program tersebut, pemerintah membutuhkan sarana transportasi yang efisien dan salah satu alat transportasi tersebut adalah kapal 3-in-1. Kapal ini diharapkan mampu menjadi sarana transportasi dan juga sarana dalam pendistribusian barang dari Jawa ke Indonesia Timur sehingga mampu meningkatkan ekonomi di Indonesia bagian timur khususnya. Kapal 3-in-1 ini akan berangkat dari Pelabuhan Tanjung Perak, Surabaya menuju Pelabuhan Lembar, Lombok dengan kecepatan 17 knot. Dalam mendesain kapal dilakukan analisis teknis dan juga analisis ekonomis berupa menghitung biaya pembangunan kapal. Kapal yang didesain memiliki ukuran utama Length of Waterline (LWL: 130 meter, length of perpendicular (LPP: 125 meter, Breadth (B: 22 meter, Height (H: 11.7 meter, dan Draft (T: 6.6 meter. Dengan ukuran tersebut kapal ini mampu mengangkut penumpang sebanyak 488 orang, kontainer sebanyak 161 TEUs, dan semen sebanyak 3200 ton (di dalam bentuk sak di mana 1 sak semen sama dengan 40 kg. Dengan ukuran dan jumlah muatan tersebut seluruh regulasi dan ketentuan teknis telah terpenuhi. Besar biaya pembangunan kapal adalah sebesar Rp 77,302,629,498.00.

  20. Using continuous UV extinction measurements to monitor and control the aerated phase of sequencing batch reactors; Einsatz der kontinuierlichen UV-Extinktionsmessung fuer die Ueberwachung und Regelung der Belueftungsphase in SBR-Anlagen

    Energy Technology Data Exchange (ETDEWEB)

    Nicolet, L.; Rott, U. [Stuttgart Univ. (Germany). Inst. fuer Siedlungswasserbau, Wasserguete- und Abfallwirtschaft; Bardeck, S. [Optek-Danulat GmbH (Germany)

    1999-07-01

    The work describes the measurement of UV extinction - expressed as the spectral absorption coefficient SAC - at a randomly chosen wave length as a technique for monitoring organic load in effluents from sequencing batch reactors (SBR) at municipal and industrial waste water treatment plants. Further described is to what extent the continuous determination of the SAC can be used in practice for the control of the aerated phase of sequencing batch reactors. By this means, process stabilization and optimization can be achieved and operating reliability can be enhanced. (orig.) [German] Inhalt dieses Beitrages ist es, die Messung der UV-Extinktion - ausgedrueckt durch den spektralen Absorptionskoeffizient (SAK) - bei einer frei gewaehlten Wellenlaenge als Verfahren fuer die Ueberwachung der organischen Belastung in den Ablaeufen von SBR-Anlagen (Sequencing-Batch-Reactor) in der kommunalen und industriellen Abwasserreinigung vorzustellen. Weiterhin soll dargestellt werden, in wieweit die kontinuierliche Bestimmung des SAK in der Praxis fuer die Regelung der beluefteten Phase von SBR-Anlagen eingesetzt werden kann. Hiermit kann eine Prozessstabilisierung und -optimierung der Anlagen erreicht sowie die Betriebssicherheit erhoeht werden. (orig.)

  1. Ciudadanas y heroinas antifranquistas: morir por la república española

    Directory of Open Access Journals (Sweden)

    Ana Aguado

    2008-12-01

    Full Text Available This text raises the analysis of historical context and biographical characterization of several women considered as “republican heroines”. This women died because of their anti-Franco identity and their link with Spanish second Republic; that is, because of their political commitment and their defence of freedom. Women who died because of the same Franco violence during both the civil war and the repression developed after the war and the victory of the revolted. The case of photographer Gerda Taro, Robert Capa’s colleague, is analyzed like this; with another few cases of women who died in the postwar, executed because of their antifascist militancy, like Águeda Campos, POUM’s militant executed in 1941, or María Pérez Lacruz, “La Jabalina”, young libertarian executed in 1942.

  2. Ciudadanas y heroinas antifranquistas: morir por la república española

    Directory of Open Access Journals (Sweden)

    Ana Aguado

    2009-04-01

    Full Text Available This text raises the analysis of historical context and biographical characterization of several women considered as “republican heroines”. This women died because of their anti-Franco identity and their link with Spanish second Republic; that is, because of their political commitment and their defence of freedom. Women who died because of the same Franco violence during both the civil war and the repression developed after the war and the victory of the revolted. The case of photographer Gerda Taro, Robert Capa’s colleague, is analyzed like this; with another few cases of women who died in the postwar, executed because of their antifascist militancy, like Águeda Campos, POUM’s militant executed in 1941, or María Pérez Lacruz, “La Jabalina”, young libertarian executed in 1942.

  3. Compiling a national resistivity atlas of Denmark based on airborne and ground-based transient electromagnetic data

    DEFF Research Database (Denmark)

    Barfod, Adrian; Møller, Ingelise; Christiansen, Anders Vest

    2016-01-01

    We present a large-scale study of the petrophysical relationship of resistivities obtained from densely sampled ground-based and airborne transient electromagnetic surveys and lithological information from boreholes. The overriding aim of this study is to develop a framework for examining...... the resistivity-lithology relationship in a statistical manner and apply this framework to gain a better description of the large-scale resistivity structures of the subsurface. In Denmark very large and extensive datasets are available through the national geophysical and borehole databases, GERDA and JUPITER...... respectively. In a 10 by 10 km grid, these data are compiled into histograms of resistivity versus lithology. To do this, the geophysical data are interpolated to the position of the boreholes, which allows for a lithological categorization of the interpolated resistivity values, yielding different histograms...

  4. Should governments in Europe be more aggressive in pushing for gender equality to raise fertility? The second "YES"

    Directory of Open Access Journals (Sweden)

    Livia Sz. Oláh

    2011-02-01

    Full Text Available This paper is based on my contribution to a debate, organized by MPIDR, on the question displayed in the title above. I was asked to present arguments for the "yes"-response (together with Laurent Toulemon, and arguing against the "no"-side represented by Gerda Neyer and Dimiter Philipov. As pointed out in the paper, the most important theoretical reasoning relevant for this question is the gender equity theory. A number of studies provide sound empirical support to it, as discussed in the paper in details, and thereby also a rationale for a positive impact of increased gender equality on fertility. As the dual-earner family is here to stay, and given the well-known negative consequences of long-term very low fertility for a society, pushing for gender equality seems to be a reasonable strategy to be considered aiming for sustainable societal development.

  5. Conceptions and tendencies of age discrimination and attitudes

    Directory of Open Access Journals (Sweden)

    Fredrik Nils Christian Snellman

    2013-11-01

    Full Text Available This study aims to access and explore tendencies in the conceptualization of age discrimination and the perceived attitudes towards older people in regions of Finland and Sweden. The analysis draws on GERDA survey data (GErontological Regional DAtabase, a repeated cross-sectional study in which data was collected in 2005 and 2010. The results indicate that the conceptions of age discrimination are changing in a positive direction, which is contrary to results shown in the Eurobarometer. On the basis of balance coefficients we show that conceived attitudes towards older people are changing as well, except for individuals in some sub-groups. We discuss the role of political rhetoric in relation to ageing awareness, the (nonindividualization of society and the negotiation of age relations as tentative interpretations that strongly challenge the observed empirical tendencies.

  6. Mida tähendab teile erialaajakiri "Raamatukogu"?

    Index Scriptorium Estoniae

    2003-01-01

    Vastavad Raplamaa Kabala Raamatukogu juhataja Hele-Mai Truuts, Orissaare Raamatukogu rmtk-hoidja Sirje Tarvis, Lihula Linnaraamatukogu juhataja Ulvi Heinmaa, Vastse-Kuuste Raamatukogu juhataja Mall Kõpp ; nr. 2, lk. 29 vastavad Tallinna Keskraamatukogu Kännukuke raamatukogu juhataja Shvea Sogenbits, Tartu Linna Keskraamatukogu asedirektor Õie Tammissaar, Viljandi Kultuurikolledzhi õppejõud Aivi Sepp ; nr. 3, lk. 27 vastavad TPÜ infoteaduste osakonna professor Aira Lepik, RRi avalike suhete osakonna juhataja Urve Pals, ELTK direktor Anne Rande ; nr. 4, lk. 22 vastavad EPMÜRi juhataja Tiina Tohvre, TTÜRi asedirektor Gerda Koidla, ELNET Konsortsiumi tegevdirektor Riin Olonen ; nr. 5, lk. 27 vastavad: Eesti Muusikaakadeemia Raamatukogu juhataja Ilvi Rauna ja RRi hoiuosakonna juhataja Krista Kats

  7. Genetic diversity and population structure of Nuphar submersa (Nymphaeaceae), a critically endangered aquatic plant endemic to Japan, and implications for its conservation.

    Science.gov (United States)

    Shiga, Takashi; Yokogawa, Masashi; Kaneko, Shingo; Isagi, Yuji

    2017-01-01

    Nuphar submersa (Nymphaeaceae) is a critically endangered freshwater macrophyte indigenous to central Japan, with only four small extant populations represented across its entire range. We investigated the genotypic and genetic diversity as well as the genetic structure of all extant individuals of N. submersa based on analysis of 15 microsatellite loci. Among 278 individual ramets, 52 multilocus genotypes were detected: 30 genotypes in Nikko City (NIK), 18 in Nasukarasuyama City (NAS), 3 in Mooka City (MOK), and 1 in Sakura City (SAK). The average number of alleles per locus ranged from 1.20 to 1.93, whereas the observed and expected heterozygosities ranged from 0.11 to 0.33 and from 0.10 to 0.24, respectively. With the exception of SAK, all populations contained multiple clones, but our results indicated low levels of within-population genetic diversity. The populations NIK and NAS comprised few large or middle-sized genets and many small genets. The populations NIK and NAS were suggested to comprise large old, old fragmented, and/or young small genets resulting from seedling establishment. All four populations were differentiated, and gene flow between the populations was restricted (average level of gene flow (Nm) = 0.122, G' ST  = 0.639). Of the total genetic diversity, 67.20 and 9.13% were attributable to inter- and intra-population diversity, respectively. STRUCTURE analysis revealed two or three well-differentiated groups of populations. Cluster I comprised one population (NIK) and cluster II comprised the remaining populations at K = 2. The populations NIK, NAS, and the remaining populations were assigned to clusters I, II, and III, respectively, at K = 3. For conservation practices, we recommend that each cluster be regarded as a different management unit. We further suggest that artificial gene flow among MOK and SAK populations is an appropriate option, whereas NIK should not be reinforced with genotypes from the remaining populations.

  8. Gıda Zehirlenmeleri

    Directory of Open Access Journals (Sweden)

    Necati Akbulut

    2015-02-01

    Full Text Available Gıda Teknolojisinin gelişmesi ile, gıda maddesinin tüketici için daha alımlı olmasını sağlamak, kısa zamanda bozulmasını engellemek ve pazara yeni çeşitler sunmak için bazı kimyasal maddeler kullanılmaya başlanılmıştır. Bunun yanında tarımda kullanılan kimyasal maddeler artmış, ambalaj sanayi gelişmiş, bu da gıda maddelerine bulaşan maddelerin türlerini arttırmıştır. Ayrıca gıda maddelerine belirli amacı olmadan katılan maddelerde vardır. Diğer taraftan tüketiciyi aldatmak, hile yapmak, çok kar sağlamak veya kötü kaliteyi gizlemek amacı ile de kullanılan maddeler bulunmaktadır. İster teknik zorunluk, ister hile amacıyla olsun bu tür yabancı maddeler öncelikle insan sağlığını ilgilendirmektedir. Bazı maddelerin vücuda alınması sakıncasız olduğu halde, bazıları sakıncalıdır. Sakıncasız olanlarında belirli bir sınırın üzerinde uzun süre alınmaları zararlı olabilmektedir. Bu toplum sağlığı sorunu birçok ülkeyi gıda sanayiinde kullanılan kimyasal maddelerin hoşgörü sınırlarının hesaplanması noktasına götürmüştür.

  9. Stabilizör Kullanımının Yoğurtların Bazı Kalite Kriterleri Üzerine Etkileri

    Directory of Open Access Journals (Sweden)

    Mehmet Güven

    2015-02-01

    Full Text Available Bu çalışmada stabilizör madde olarak %0.5 jelatin, %0.2 pektin, %0.5 arap sakızı, %0.15 karragenan ve emilsüfiyer madde olarak %0.5 lesitin kullanımının yoğurtların bazı özelliklerine etkileri ve bu özelliklerinin 21 günlük depolama sırasındaki değişimi incelenmiştir. Karragenanın yoğurtlarda asitlik gelişimini ve pH’nın düşmesini engellediği; jelatin, arap sakızı ve karragenanın pıhtı sertliğini, jelatin ve arap sakızının viskoziteyi, karragenanın su salma özelliğini olumlu yönde etkilediği belirlenmiştir. Lesitinin de pıhtı sertliğini ve viskoziteyi iyileştirdiği görülmüştür. Karragenanın duyusal özelliklerin bozulmasına neden olduğu belirlenmiş, en çok beğenilen jelatini yoğurtlar olurken, diğerleri kontrole yakın değerler almışlardır. Depolama süresince yoğurtların titrasyon asitlikleri ve pıhtı sertlikleri yükselmiş pH değeri laktoz oranı ve su salma miktarı azalmıştır. Duyusal özelliklerin uzun süreli depolamadan olumsuz yönde etkilendiği belirlenmiştir.

  10. Tinjauan Hukum Islam terhadap Perkawinan Beda Kelas Muslim Sasak di Lombok

    Directory of Open Access Journals (Sweden)

    Basriadi Basriadi

    2015-08-01

    Full Text Available This article attempts to examine in depth, based on the theory of kafâ‘ah, different class marriages in the Sasak Muslim community, Lombok. The study concludes that on one hand, the different class marriages between noblewomen and non-noblemen do not have an impact on the purpose of marriage which is to create sakînah, mawaddah, and rahmah household. On the other hand, the marriage that is based on Islamic values is able to realize a happy and harmonious household regardless of social status background. The most important thing in domestic life is communication and trust between husbands and wives. In fiqh munâkah}ât, it is required when someone is looking for a spouse, something that needs to be seen is lineage, beauty, wealth and religion. This article would like to emphasize that there is no prohibition in Islam to marry people of different social class.

  11. Toward a model of employee engagement in a public service organization

    DEFF Research Database (Denmark)

    Nielsen, Mette Strange

    Employee engagement has long been capturing the attention of researchers and practitioners, (e.g. Bakker, Albrecht, & Leiter, 2011; Buckingham & Coffman, 1999) due to its positive impact on various measures of organizational performance (Gruman & Saks, 2011; Harter, Schmidt, & Hayes, 2002; Mone...... & London, 2010). To date, however, employee engagement has primarily been studied in private manufacturing firms leaving out a gap of research in a public service organization, such as eldercare organizations, although engagement according to Boselie (2010) is highly relevant in the specific context....... The purpose of the PhD project is to build a model explaining employee engagement in a public service organization. Research on work design theory (e.g. Hackman & Oldham, 1976) will be used, since it has often been applied to identify antecedents associated with engagement (Bakker & Demerouti, 2007; Kahn...

  12. Exponential Lower Bounds for the PPSZ k-SAT Algorithm

    DEFF Research Database (Denmark)

    Chen, Shiteng; Scheder, Dominik Alban; Talebanfard, Navid

    2013-01-01

    In 1998, Paturi, Pudl´ak, Saks, and Zane presented PPSZ, an elegant randomized algorithm for k-SAT. Fourteen years on, this algorithm is still the fastest known worst-case algorithm. They proved that its expected running time on k-CNF formulas with n variables is at most 2(1−k)n, where k 2 (1/k).......). So far, no exponential lower bounds at all have been known. In this paper, we construct hard instances for PPSZ. That is, we construct satisfiable k-CNF formulas over n variables on which the expected running time is at least 2(1−k)n, for k 2 O(log2 k/k)....

  13. Flavour-active wine yeasts.

    Science.gov (United States)

    Cordente, Antonio G; Curtin, Christopher D; Varela, Cristian; Pretorius, Isak S

    2012-11-01

    The flavour of fermented beverages such as beer, cider, saké and wine owe much to the primary fermentation yeast used in their production, Saccharomyces cerevisiae. Where once the role of yeast in fermented beverage flavour was thought to be limited to a small number of volatile esters and higher alcohols, the discovery that wine yeast release highly potent sulfur compounds from non-volatile precursors found in grapes has driven researchers to look more closely at how choice of yeast can influence wine style. This review explores recent progress towards understanding the range of 'flavour phenotypes' that wine yeast exhibit, and how this knowledge has been used to develop novel flavour-active yeasts. In addition, emerging opportunities to augment these phenotypes by engineering yeast to produce so-called grape varietal compounds, such as monoterpenoids, will be discussed.

  14. Palaeomagnetism of Upper Cretaceous volcanic rocks from Cabo de Sto. Agostinho, Brazil

    Science.gov (United States)

    Schult, A.; Guerreiro, S. D. C.

    1980-10-01

    One hundred samples from nine sites in Upper Cretaceous volcanics (K/Ar age 85-99 m.y.) of the magmatic province of Cabo de Santo Agostinho, Pernambuco (8.4°S, 35.0°W) yield a mean direction of magnetization D = 0.4°, I = -20.6°withα 95 = 4.8°, k = 114 after AF cleaning. All sites have normal polarity with a mean pole, named SAK 10, at 87.6°N, 135°E with A 95 = 4.5° which is close to other Upper Cretaceous poles for South America. These poles are compared with Upper Cretaceous poles of Africa for various reconstructions of the two continents.

  15. Orlicz difference sequence spaces generated by infinite matrices and de la Vallée-Poussin mean of order α

    Directory of Open Access Journals (Sweden)

    Bipan Hazarika

    2016-10-01

    Full Text Available In this paper we introduce the spaces V^λ[A,M,Δ,p]o,V^λ[A,M,Δ,p] and V^λ[A,M,Δ,p]∞ generated by infinite matrices defined by Orlicz functions. Also we introduce the concept of S^λ[A,Δ]−convergence and derive some results between the spaces S^λ[A,Δ] and V^λ[A,Δ]. Further, we study some geometrical properties such as order continuity, the Fatou property and the Banach–Saks property of the new space V^λα[A,Δ,p]∞. Finally, we introduce the notion of almost λ-statistically-[A, Δ]-convergence of order α or S^λα[A,Δ]−convergence and obtain some inclusion relations between the set S^λα[A,Δ] and the space V^λα[A,Δ,p]∞.

  16. Understanding employee engagement in a public service context

    DEFF Research Database (Denmark)

    Nielsen, Mette Strange

    Employee engagement has long been capturing the attention of researchers and practitioners (Bakker, Albrecht, & Leiter, 2011; Kahn, 1990), due to its positive impact on various measures of organizational performance and individual level outcomes (Gruman & Saks, 2011; Harter, Schmidt, & Hayes, 2002......). To date however, employee engagement has primarily been studied in private manufacturing firms, but since it cannot be assumed that employee engagement models developed in the private sector are applicable to the public sector (Boselie, 2010; Taher & Emmert, 1992), future research is needed. The purpose...... of this paper is therefore to build a research agenda aiming to understand employee engagement in a public service context. The paper begins with a literature review of the main contributions to the study of employee engagement and then follows with a brief review of the public sector, highlighting some...

  17. Editorial

    CERN Multimedia

    Staff Association

    2012-01-01

    For its fiftieth anniversary the Kindergarten and School run by the Staff Association   is in better shape than ever. The CERN site has resounded for 50 years with the joyful shouts of the children there. It is indeed in this joyful and multicultural atmosphere than many generations of children of CERN staff have followed one another all those years. Operating on one of the most beautiful sites of CERN and supervised by competent and creative professionals, the children learn through play, the basics needed for their integration into society and entry into academic learning. Active learning is the heart of the action.  Children take in knowledge as they develop and are exposed to multiple experiences. The activities proposed in the SAKS are based on a global approach to development as well as on values such as self-respect, respect towards others, the environment, autonomy, sharing, cooperation, communication and creativity. In the large, specially designed garden surrounding...

  18. Alaska North Slope National Energy Strategy initiative: Analysis of five undeveloped fields

    International Nuclear Information System (INIS)

    Thomas, C.P.; Allaire, R.B.; Doughty, T.C.; Faulder, D.D.; Irving, J.S.; Jamison, H.C.; White, G.J.

    1993-05-01

    The US Department of Energy was directed in the National Energy Strategy to establish a federal interagency task force to identify specific technical and regulatory barriers to the development of five undeveloped North Slope Alaska fields and make recommendations for their resolution. The five fields are West Sak, Point Thomson, Gwydyr Bay, Seal Island/Northstar, and Sandpiper Island. Analysis of environmental, regulatory, technical, and economic information, and data relating to the development potential of the five fields leads to the following conclusions: Development of the five fields would result in an estimated total of 1,055 million barrels of oil and 4.4 trillion cubic feet of natural gas and total investment of $9.4 billion in 1992 dollars. It appears that all five of the fields will remain economically marginal developments unless there is significant improvement in world oil prices. Costs of regulatory compliance and mitigation, and costs to reduce or maintain environmental impacts at acceptable levels influence project investments and operating costs and must be considered in the development decision making process. The development of three of the fields (West Sak, Point Thomson, and Gwydyr Bay) that are marginally feasible would have an impact on North Slope production over the period from about 2000 to 2014 but cannot replace the decline in Prudhoe Bay Unit production or maintain the operation of the Trans-Alaska Pipeline System (TAPS) beyond about 2014 with the assumption that the TAPS will shut down when production declines to the range of 400 to 200 thousand barrels of oil/day. Recoverable reserves left in the ground in the currently producing fields and soon to be developed fields, Niakuk and Point McIntyre, would range from 1 billion to 500 million barrels of oil corresponding to the time period of 2008 to 2014 based on the TAPS shutdown assumption

  19. El léxico cromático y la ideología maya Chromatic lexic and Maya ideology

    Directory of Open Access Journals (Sweden)

    Sanja Savkic

    2011-01-01

    Full Text Available Para acercarse al campo semántico de los colores, de primera importancia son diversos diccionarios de las lenguas mayances. El objetivo es hacer una descripción preliminar del vocabulario cromático, compuesto de cinco términos referidos a colores básicos que en el maya yucateco se llaman sak, ek', chak, k'an y ya'ax y significan "blanco", "negro", "rojo", "amarillo" y "verde-azul", respectivamente. El mismo vocabulario remite a determinadas categorías extralingüísticas que la lengua es capaz de acumular, reflejar y comunicar. Éstas dependen de una cultura particular, por lo que el estudio se amplía con las informaciones de diferentes fuentes escritas redactadas durante la época colonial. La intención es detectar los múltiples usos que se hacían en todos los ámbitos de la vida de los colores, lo cual a su vez permite considerar estos últimos como conceptualizaciones articuladas en pares de oposición o agrupamientos tripartitos.To gain greater insight into the color semantic field, it is important to consult various Mayance language dictionaries, in order to assemble a preliminary chromatic vocabulary, composed of five basic color terms which in Yucatec Maya are sak, ek', chak, k'an and ya'ax, or "white", "black", "red", "yellow" and "green-blue", respectively. The very vocabulary addresses certain extra-linguistic categories that language is capable of accumulating, reflecting, and communicating. These categories depend on a particular culture; consequently this study is amplified with greater information from different sources written during the colonial period in order to shed light on the many uses that the colors had in the aspects of human life which, at the same time, can be seen in conceptualizations articulated in pairs of opposition or tripartite groupings.

  20. Selection indicates preference in diverse habitats: a ground-nesting bird (Charadrius melodus) using reservoir shoreline.

    Science.gov (United States)

    Anteau, Michael J; Sherfy, Mark H; Wiltermuth, Mark T

    2012-01-01

    Animals use proximate cues to select resources that maximize individual fitness. When animals have a diverse array of available habitats, those selected could give insights into true habitat preferences. Since the construction of the Garrison Dam on the Missouri River in North Dakota, Lake Sakakawea (SAK) has become an important breeding area for federally threatened piping plovers (Charadrius melodus; hereafter plovers). We used conditional logistic regression to examine nest-site selection at fine scales (1, 3, and 10 m) during summers 2006-2009 by comparing characteristics at 351 nests to those of 668 random sites within nesting territories. Plovers selected sites (1 m(2)) that were lower than unused random sites, increasing the risk of nest inundation. Plovers selected nest sites that were flat, had little silt, and at least 1 cobble; they also selected for 3-m radius nest areas that were relatively flat and devoid of vegetation and litter. Ninety percent of nests had <38% coverage of silt and <10% slope at the site, and <15% coverage of vegetation or litter and <31% slope within the 3-m radius. Gravel was selected for at nest sites (11% median), but against in the area 10-m from the nest, suggesting plovers select for patches or strips of gravel. Although elevation is rarely evaluated in studies of ground-nesting birds, our results underscore its importance in habitat-selection studies. Relative to where plovers historically nested, habitat at SAK has more diverse topography, substrate composition, vegetation communities, and greater water-level fluctuations. Accordingly, our results provide an example of how habitat-selection results can be interpreted as habitat preferences because they are not influenced by desired habitats being scarce or absent. Further, our results will be useful for directing habitat conservation for plovers and interpreting other habitat-selection studies.

  1. The response regulator BcSkn7 is required for vegetative differentiation and adaptation to oxidative and osmotic stresses in Botrytis cinerea.

    Science.gov (United States)

    Yang, Qianqian; Yin, Dafang; Yin, Yanni; Cao, Yi; Ma, Zhonghua

    2015-04-01

    The high-osmolarity glycerol pathway plays an important role in the responses of fungi to various environmental stresses. Saccharomyces cerevisiae Skn7 is a response regulator in the high-osmolarity glycerol pathway, which regulates the oxidative stress response, cell cycle and cell wall biosynthesis. In this study, we characterized an Skn7 orthologue BcSkn7 in Botrytis cinerea. BcSKN7 can partly restore the growth defects of S. cerevisiae SKN7 mutant and vice versa. The BcSKN7 mutant (ΔBcSkn7-1) revealed increased sensitivity to ionic osmotic and oxidative stresses and to ergosterol biosynthesis inhibitors. In addition, ΔBcSkn7-1 was also impaired dramatically in conidiation and sclerotial formation. Western blot analysis showed that BcSkn7 positively regulated the phosphorylation of BcSak1 (the orthologue of S. cerevisiae Hog1) under osmotic stress, indicating that BcSkn7 is associated with the high-osmolarity glycerol pathway in B. cinerea. In contrast with BcSak1, BcSkn7 is not involved in the regulation of B. cinerea virulence. All of the phenotypic defects of ΔBcSkn7-1 are restored by genetic complementation of the mutant with the wild-type BcSKN7. The results of this study indicate that BcSkn7 plays an important role in the regulation of vegetative differentiation and in the response to various stresses in B. cinerea. © 2014 BSPP AND JOHN WILEY & SONS LTD.

  2. Alaska North Slope National Energy Strategy initiative: Analysis of five undeveloped fields

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, C.P.; Allaire, R.B.; Doughty, T.C.; Faulder, D.D.; Irving, J.S.; Jamison, H.C.; White, G.J.

    1993-05-01

    The US Department of Energy was directed in the National Energy Strategy to establish a federal interagency task force to identify specific technical and regulatory barriers to the development of five undeveloped North Slope Alaska fields and make recommendations for their resolution. The five fields are West Sak, Point Thomson, Gwydyr Bay, Seal Island/Northstar, and Sandpiper Island. Analysis of environmental, regulatory, technical, and economic information, and data relating to the development potential of the five fields leads to the following conclusions: Development of the five fields would result in an estimated total of 1,055 million barrels of oil and 4.4 trillion cubic feet of natural gas and total investment of $9.4 billion in 1992 dollars. It appears that all five of the fields will remain economically marginal developments unless there is significant improvement in world oil prices. Costs of regulatory compliance and mitigation, and costs to reduce or maintain environmental impacts at acceptable levels influence project investments and operating costs and must be considered in the development decision making process. The development of three of the fields (West Sak, Point Thomson, and Gwydyr Bay) that are marginally feasible would have an impact on North Slope production over the period from about 2000 to 2014 but cannot replace the decline in Prudhoe Bay Unit production or maintain the operation of the Trans-Alaska Pipeline System (TAPS) beyond about 2014 with the assumption that the TAPS will shut down when production declines to the range of 400 to 200 thousand barrels of oil/day. Recoverable reserves left in the ground in the currently producing fields and soon to be developed fields, Niakuk and Point McIntyre, would range from 1 billion to 500 million barrels of oil corresponding to the time period of 2008 to 2014 based on the TAPS shutdown assumption.

  3. Bacteriocin production and inhibition of Listeria monocytogenes by Lactobacillus sakei subsp. sakei 2a in a potentially synbiotic cheese spread.

    Science.gov (United States)

    Martinez, Rafael Chacon Ruiz; Staliano, Cristina Dini; Vieira, Antonio Diogo Silva; Villarreal, Martha Lissete Morales; Todorov, Svetoslav Dimitrov; Saad, Susana Marta Isay; Franco, Bernadette Dora Gombossy de Melo

    2015-06-01

    Survival, bacteriocin(s) production, and antilisterial effect of Lactobacillus sakei subsp. sakei 2a were evaluated in a potentially synbiotic cheese spread, throughout storage at 4 °C and 15 °C for up to 28 days, using culture-dependent (plate count) and culture-independent (qPCR) methods. Bacteriocin(s) production in the food product was monitored by phenotypic and molecular (RT-qPCR) techniques. Three cheese spread trials (T) containing the prebiotic fiber inulin were produced in duplicates and studied: T1 (control - without inoculation of lactic acid bacteria); T2 (inoculated with the non-bacteriocinogenic Lb. sakei ATCC 15521 strain), and T3 (inoculated with the bacteriocinogenic Lb. sakei 2a strain). The cheese spreads were challenged with Listeria monocytogenes serotypes 4b and 1/2a, individually added to the food product. The counts of Lb. sakei 2a in the cheese spread T3 remained high during storage and the growth of L. monocytogenes was inhibited at both temperatures, especially L. monocytogenes 4b in the food product kept at 15 °C due to the production of bacteriocins (up to 6,400 AU/mL). Expression of the genes sakP and sakQ encoding for bacteriocins production during the cheese spread storage was demonstrated. Lb. sakei 2a can be used for production of potentially synbiotic cheese spreads with increased safety. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Selection indicates preference in diverse habitats: a ground-nesting bird (Charadrius melodus using reservoir shoreline.

    Directory of Open Access Journals (Sweden)

    Michael J Anteau

    Full Text Available Animals use proximate cues to select resources that maximize individual fitness. When animals have a diverse array of available habitats, those selected could give insights into true habitat preferences. Since the construction of the Garrison Dam on the Missouri River in North Dakota, Lake Sakakawea (SAK has become an important breeding area for federally threatened piping plovers (Charadrius melodus; hereafter plovers. We used conditional logistic regression to examine nest-site selection at fine scales (1, 3, and 10 m during summers 2006-2009 by comparing characteristics at 351 nests to those of 668 random sites within nesting territories. Plovers selected sites (1 m(2 that were lower than unused random sites, increasing the risk of nest inundation. Plovers selected nest sites that were flat, had little silt, and at least 1 cobble; they also selected for 3-m radius nest areas that were relatively flat and devoid of vegetation and litter. Ninety percent of nests had <38% coverage of silt and <10% slope at the site, and <15% coverage of vegetation or litter and <31% slope within the 3-m radius. Gravel was selected for at nest sites (11% median, but against in the area 10-m from the nest, suggesting plovers select for patches or strips of gravel. Although elevation is rarely evaluated in studies of ground-nesting birds, our results underscore its importance in habitat-selection studies. Relative to where plovers historically nested, habitat at SAK has more diverse topography, substrate composition, vegetation communities, and greater water-level fluctuations. Accordingly, our results provide an example of how habitat-selection results can be interpreted as habitat preferences because they are not influenced by desired habitats being scarce or absent. Further, our results will be useful for directing habitat conservation for plovers and interpreting other habitat-selection studies.

  5. Investigation of advanced materials for fusion alpha particle diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Bonheure, G., E-mail: g.bonheure@fz-juelich.de [Laboratory for Plasma Physics, Association “Euratom-Belgian State”, Royal Military Academy, Avenue de la Renaissance, 30 Kunstherlevinglaan, B-1000 Brussels (Belgium); Van Wassenhove, G. [Laboratory for Plasma Physics, Association “Euratom-Belgian State”, Royal Military Academy, Avenue de la Renaissance, 30 Kunstherlevinglaan, B-1000 Brussels (Belgium); Hult, M.; González de Orduña, R. [Institute for Reference Materials and Measurements (IRMM), Retieseweg 111, B-2440 Geel (Belgium); Strivay, D. [Centre Européen d’Archéométrie, Institut de Physique Nucléaire, Atomique et de Spectroscopie, Université de Liège (Belgium); Vermaercke, P. [SCK-CEN, Boeretang, B-2400 Mol (Belgium); Delvigne, T. [DSI SPRL, 3 rue Mont d’Orcq, Froyennes B-7503 (Belgium); Chene, G.; Delhalle, R. [Centre Européen d’Archéométrie, Institut de Physique Nucléaire, Atomique et de Spectroscopie, Université de Liège (Belgium); Huber, A.; Schweer, B.; Esser, G.; Biel, W.; Neubauer, O. [Forschungszentrum Jülich GmbH, Institut für Plasmaphysik, EURATOM-Assoziation, Trilateral Euregio Cluster, D-52425 Jülich (Germany)

    2013-10-15

    Highlights: ► We examine the feasibility of alpha particle measurements in ITER. ► We test advanced material detectors borrowed from the GERDA neutrino experiment. ► We compare experimental results on TEXTOR tokamak with our detector response model. ► We investigate the detector response in ITER full power D–T plasmas. ► Advanced materials show good signal to noise ratio and alpha particle selectivity. -- Abstract: Fusion alpha particle diagnostics for ITER remain a challenging task. Standard escaping alpha particle detectors in present tokamaks are not applicable to ITER and techniques suitable for fusion reactor conditions need further research and development [1,2]. The activation technique is widely used for the characterization of high fluence rates inside neutron reactors. Tokamak applications of the neutron activation technique are already well developed [3] whereas measuring escaping ions using this technique is a novel fusion plasma diagnostic development. Despite low alpha particle fluence levels in present tokamaks, promising results using activation technique combined with ultra-low level gamma-ray spectrometry [4] were achieved before in JET [5,6]. In this research work, we use new advanced detector materials. The material properties beneficial for alpha induced activation are (i) moderate neutron cross-sections (ii) ultra-high purity which reduces neutron-induced background activation and (iii) isotopic tailoring which increases the activation yield of the measured activation product. Two samples were obtained from GERDA[7], an experiment aimed at measuring the neutrinoless double beta decay in {sup 76}Ge. These samples, made of highly pure (9 N) germanium highly enriched to 87% in isotope Ge-76, were irradiated in real D–D fusion plasma conditions inside the TEXTOR tokamak. Comparison of the calculated and the experimentally measured activity shows good agreement. Compared to previously investigated high temperature ceramic material [8

  6. Pulse shape discrimination performance of inverted coaxial Ge detectors

    Science.gov (United States)

    Domula, A.; Hult, M.; Kermaïdic, Y.; Marissens, G.; Schwingenheuer, B.; Wester, T.; Zuber, K.

    2018-05-01

    We report on the characterization of two inverted coaxial Ge detectors in the context of being employed in future 76Ge neutrinoless double beta (0 νββ) decay experiments. It is an advantage that such detectors can be produced with bigger Ge mass as compared to the planar Broad Energy Ge (BEGe) or p-type Point Contact (PPC) detectors that are currently used in the GERDA and MAJORANA DEMONSTRATOR 0 νββ decay experiments respectively. This will result in a lower background for the search of 0 νββ decay due to a reduction of detector surface to volume ratio, cables, electronics and holders which are dominating nearby radioactive sources. The measured resolution near the 76Ge Q-value at 2039 keV is 2.3 keV FWHM and their pulse-shape discrimination of background events are similar to BEGe and PPC detectors. It is concluded that this type of Ge-detector is suitable for usage in 76Ge 0 νββ decay experiments.

  7. Wilcoxon signed-rank-based technique for the pulse-shape analysis of HPGe detectors

    Energy Technology Data Exchange (ETDEWEB)

    Martín, S., E-mail: sergiomr@usal.es; Quintana, B.; Barrientos, D.

    2016-07-01

    The characterization of the electric response of segmented-contact high-purity germanium detectors requires scanning systems capable of accurately associating each pulse with the position of the interaction that generated it. This process requires an algorithm sensitive to changes above the electronic noise in the pulse shapes produced at different positions, depending on the resolution of the Ge crystal. In this work, a pulse-shape comparison technique based on the Wilcoxon signed-rank test has been developed. It provides a method to distinguish pulses coming from different interaction points in the germanium crystal. Therefore, this technique is a necessary step for building a reliable pulse-shape database that can be used later for the determination of the position of interaction for γ-ray tracking spectrometry devices such as AGATA, GRETA or GERDA. The method was validated by comparison with a χ{sup 2} test using simulated and experimental pulses corresponding to a Broad Energy germanium detector (BEGe).

  8. Inelastic neutron scattering cross-section measurements on 7Li and 63,65Cu

    Directory of Open Access Journals (Sweden)

    Nyman Markus

    2017-01-01

    Full Text Available The γ-ray production cross section for the 477.6-keV transition in 7Li following inelastic neutron scattering has been measured from the reaction threshold up to 18 MeV. This cross section is interesting as a possible standard for other inelastic scattering measurements. The experiment was conducted at the Geel Electron LINear Accelerator (GELINA pulsed white neutron source with the Gamma Array for Inelastic Neutron Scattering (GAINS spectrometer. Previous measurements of this cross section are reviewed and compared with our results. Recently, this cross section has also been calculated using the continuum discretized coupled-channels (CDCC method. Experiments for studying neutrinoless double-β decay (2β0ν or other very rare processes require greatly reducing the background radiation level (both intrinsic and external. Copper is a common shielding and structural material, used extensively in experiments such as COBRA, CUORE, EXO, GERDA, and MAJORANA. Understanding the background contribution arising from neutron interactions in Cu is important when searching for very weak experimental signals. Neutron inelastic scattering on natCu was investigated with GAINS. The results are compared with previous experimental data and evaluated nuclear data libraries.

  9. [Updates on the earlier treatments for atopic dermatitis].

    Science.gov (United States)

    Jelen, G

    1998-01-01

    The GERDA classes have the function of updating our knowledge of dermato-allergology. One of the themes tackled this year was the treatment of atopic dermatitis. Apart from consideration of treatment or exception with cortisone, it seemed to be of interest to find the relevance of "old treatments" for atopic dermatitis, either preventive or symptomatic. Preventive treatment made reference to correction of food factors (diet in infants, removal of maternal allergens, supplementation on fatty acids) and of environmental factors especially the fight against house dust mites by use of anti-mite mattress covers. Miracle treatments of atopy do not always exist. Thus there is often need for, besides local corticosteroid therapy, an external symptomatic treatment where the emphasis is on the struggle against skin microbiology, the fight against pruritic inflammatory conditions and above all the battle against xerosis. Knowledge of the physiology of the stratum corneum gives better understanding of the effect of emollients and moisturizers in restoration of the cutaneous barrier, of which dysfunction is one of the elements of atopic dermatitis.

  10. Prevalence of loneliness over ten years among the oldest old.

    Science.gov (United States)

    Nyqvist, Fredrica; Cattan, Mima; Conradsson, Mia; Näsman, Marina; Gustafsson, Yngve

    2017-06-01

    This study examined the prevalence of loneliness among the oldest old within a 10-year period and studied the influence of various sociodemographic, social and health characteristics on loneliness. The study used population-based data from the Umeå85+/GErontological Regional DAtabase-study (GERDA) for the years 2000-2002, 2005-2007 and 2010-2012 including 85-year-old, 90-year-old and ⩾95-year-old participants. A final sample of 304 participants in 2000-2002, 329 participants in 2005-2007 and 401 participants in 2010-2012 was included in the analyses. Although the level of loneliness was already high in 2000-2002 (49.3% reported frequent loneliness), the results showed limited changes in loneliness during the 10-year study period. Loneliness was closely related to living alone, depressive symptoms and living in institutional settings. Although societal changes such as solitary living and growing urbanization suggest a changing trend in loneliness, we found that the prevalence of loneliness was relatively stable in this study. Nevertheless, loneliness is common among the oldest old and a focus on social issues related to living arrangements and on depressive symptoms is important in understanding loneliness.

  11. Standard and Nonstandard Neutrino-Nucleus Reactions Cross Sections and Event Rates to Neutrino Detection Experiments

    Directory of Open Access Journals (Sweden)

    D. K. Papoulias

    2015-01-01

    Full Text Available In this work, we explore ν-nucleus processes from a nuclear theory point of view and obtain results with high confidence level based on accurate nuclear structure cross sections calculations. Besides cross sections, the present study includes simulated signals expected to be recorded by nuclear detectors and differential event rates as well as total number of events predicted to be measured. Our original cross sections calculations are focused on measurable rates for the standard model process, but we also perform calculations for various channels of the nonstandard neutrino-nucleus reactions and come out with promising results within the current upper limits of the corresponding exotic parameters. We concentrate on the possibility of detecting (i supernova neutrinos by using massive detectors like those of the GERDA and SuperCDMS dark matter experiments and (ii laboratory neutrinos produced near the spallation neutron source facilities (at Oak Ridge National Lab by the COHERENT experiment. Our nuclear calculations take advantage of the relevant experimental sensitivity and employ the severe bounds extracted for the exotic parameters entering the Lagrangians of various particle physics models and specifically those resulting from the charged lepton flavour violating μ-→e- experiments (Mu2e and COMET experiments.

  12. Partial versus complete fundoplication for the correction of pediatric GERD: a systematic review and meta-analysis.

    Directory of Open Access Journals (Sweden)

    Peter Glen

    Full Text Available There is no consensus as to what extent of "wrap" is required in a fundoplication for correction of gastroesophageal reflux disease (GERD.To evaluate if a complete (360 degree or partial fundoplication gives better control of GERD.A systematic search of MEDLINE and Scopus identified interventional and observational studies of fundoplication in children. Screening identified those comparing techniques. The primary outcome was recurrence of GERD following surgery. Dysphagia and complications were secondary outcomes of interest. Meta-analysis was performed when appropriate. Study quality was assessed using the Cochrane Risk of Bias Tool.2289 abstracts were screened, yielding 2 randomized controlled trials (RCTs and 12 retrospective cohort studies. The RCTs were pooled. There was no difference in surgical success between partial and complete fundoplication, OR 1.33 [0.67,2.66]. In the 12 cohort studies, 3 (25% used an objective assessment of the surgery, one of which showed improved outcomes with complete fundoplication. Twenty-five different complications were reported; common were dysphagia and gas-bloat syndrome. Overall study quality was poor.The comparison of partial fundoplication with complete fundoplication warrants further study. The evidence does not demonstrate superiority of one technique. The lack of high quality RCTs and the methodological heterogeneity of observational studies limits a powerful meta-analysis.

  13. Nemo-3 experiment assets and limitations. Perspective for the double {beta} physics; Experience Nemo 3 avantage et limitations. Prospective pour la physique double {beta}

    Energy Technology Data Exchange (ETDEWEB)

    Augier, C

    2005-06-15

    After an introduction to this report in Chapter 1, I present a status of our knowledge in neutrino physics in Chapter 2. Then, I detail in Chapter 3 all the choices made for the design and realisation of the NEMO 3 detector for the research of double beta decay process. Performance of the detector is presented, concerning both the capacity of the detector to identify the backgrounds and the ability to study all the {beta}{beta} process. I also explain the methods chosen by the NEMO collaboration to reduce the radon activity inside the detector and to make this background negligible today. This chapter, which is written in English, is the 'Technical report of the NEMO 3 detector' and forms an independent report for the NEMO collaborators. I finish this report in Chapter 4 with a ten years prospect for experimental projects in physics, with both the SuperNEMO project and its experiment program, and also by comparing the most interesting experiments, CUORE and GERDA, showing as an example the effect of nuclear matrix elements on the neutrino effective mass measurement. (author)

  14. The body in the processes of musical sensitizing

    Directory of Open Access Journals (Sweden)

    Sonia Albano de Lima

    2007-05-01

    Full Text Available This article highlights part of the bibliographic collecting of Alexandre Ruger’s Master Degree dissertation entitled “The corporal percussion as a proposal of musical sensitizing for actors and theater students”, developed in the IA-UNESP (Arts Institute – State of São Paulo University. The research was supervised by Sonia Albano de Lima. The bibliographic collection was sub-divided into three items: the body and the musical teaching, the understanding of the body-mind binomial and the musical teaching in the Scenic Arts as a means of developing the expressivity and the corporal awareness. In the present text the two first items will be exposed. In the first one, the work of the educators Emile Jacques-Dalcroze (1865-1950, Carl Orff (1895-1982, Edgar Willems (1890-1978, Murray Schafer (1933-, among others, served as a theoretical subsidy, as well as the work of corporal percussion developed by the Grupo Barbatuques. In the inter-relationship between the body and the mind the theoretical foundation was taken from the texts by Paul Sivadon, from the area of Social Psychology; Jean Claude Coste, from the Psychomotility area; Patrícia Pederiva, from the musical research area; James J. Gibson, from the Psychology area; Gerda Alexander, from the Eutonia area, among others.

  15. Nemo-3 experiment assets and limitations. Perspective for the double β physics

    International Nuclear Information System (INIS)

    Augier, C.

    2005-06-01

    After an introduction to this report in Chapter 1, I present a status of our knowledge in neutrino physics in Chapter 2. Then, I detail in Chapter 3 all the choices made for the design and realisation of the NEMO 3 detector for the research of double beta decay process. Performance of the detector is presented, concerning both the capacity of the detector to identify the backgrounds and the ability to study all the ββ process. I also explain the methods chosen by the NEMO collaboration to reduce the radon activity inside the detector and to make this background negligible today. This chapter, which is written in English, is the 'Technical report of the NEMO 3 detector' and forms an independent report for the NEMO collaborators. I finish this report in Chapter 4 with a ten years prospect for experimental projects in physics, with both the SuperNEMO project and its experiment program, and also by comparing the most interesting experiments, CUORE and GERDA, showing as an example the effect of nuclear matrix elements on the neutrino effective mass measurement. (author)

  16. Methods to improve and understand the sensitivity of high purity germanium detectors for searches of rare events

    Energy Technology Data Exchange (ETDEWEB)

    Volynets, Oleksandr

    2012-07-27

    Observation of neutrinoless double beta-decay could answer fundamental questions on the nature of neutrinos. High purity germanium detectors are well suited to search for this rare process in germanium. Successful operation of such experiments requires a good understanding of the detectors and the sources of background. Possible background sources not considered before in the presently running GERDA high purity germanium detector experiment were studied. Pulse shape analysis using artificial neural networks was used to distinguish between signal-like and background-like events. Pulse shape simulation was used to investigate systematic effects influencing the efficiency of the method. Possibilities to localize the origin of unwanted radiation using Compton back-tracking in a granular detector system were examined. Systematic effects in high purity germanium detectors influencing their performance have been further investigated using segmented detectors. The behavior of the detector response at different operational temperatures was studied. The anisotropy effects due to the crystallographic structure of germanium were facilitated in a novel way to determine the orientation of the crystallographic axes.

  17. Five-year change in morale is associated with negative life events in very old age.

    Science.gov (United States)

    Näsman, Marina; Niklasson, Johan; Saarela, Jan; Nygård, Mikael; Olofsson, Birgitta; Conradsson, Mia; Lövheim, Hugo; Gustafson, Yngve; Nyqvist, Fredrica

    2017-10-27

    The objectives were to study changes in morale in individuals 85 years and older, and to assess the effect of negative life events on morale over a five-year follow-up period. The present study is based on longitudinal data from the Umeå85+/GERDA-study, including individuals 85 years and older at baseline (n = 204). Morale was measured with the Philadelphia Geriatric Center Morale Scale (PGCMS). Negative life events were assessed using an index including 13 negative life events occurring during the follow-up period. Linear regression was used for the multivariate analyses. The majority of the sample (69.1%) had no significant changes in morale during the five-year follow-up. However, the accumulation of negative life events was significantly associated with a greater decrease in PGCMS. A higher baseline PGCMS score did not attenuate the adverse effect negative life events had on morale. Morale seemed to be mainly stable in a five-year follow-up of very old people. It seems, nonetheless, that individuals are affected by negative life events, regardless of level of morale. Preventing negative life events and supporting individuals who experience multiple negative life events could have important implications for the care of very old people.

  18. TASAWUF SEBAGAI SOLUSI BAGI PROBLEMATIKA KEMODERNAN: Studi Pemikiran Tasawuf M. Amin Syukur

    Directory of Open Access Journals (Sweden)

    Umar Faruq Thohir

    2016-03-01

    Full Text Available Abstract: This article aims to elaborate Sufism thought of Amin Syukur. Hepositioned Sufismas one of the solutions to the problems of modernity who have lost the vision of divinity that result in psychological symptoms, namely spiritual emptiness. Then, the people would become stress and worry wart because of their hopless feeling. For this reason, M. Amin Syukur endorsed the problems of modernity with always optimistic, positive thinking, resting every intention and good deeds only to worship God and sharing (solidarity for fellow creatures of God. In addition, he recommends to remember (al-żikr to Godhowever, whenever, and wherever. Remembering God can calm the soul (sakīna and mind that will affect the nerve, the nerve will affect the glands, the glands will produce healthy liquid. Healthy liquid which is a calm soul effect which will make man have the "immune power" against all diseases. In medical the termis called psycho-neuroen docrine immunology. Furthermore, according to Amin Syukur, problems of modernity can besolved by Sufism through methods like ma'rifa Allāh obtained via stairs of ma'rifa al-nafs, ma'rifa al-nās, and ma'rifa al-kawn. Abstrak: Artikel bertujuan untuk mengelaborasi pemikiran tasawuf Amin Syukur. Ia memposisikan tasawuf sebagai salah satu solusi terhadap problematika kemodernan ini yang sudah kehilangan visi keilahian yang mengakibatkan timbulnya gejala psikologis, yaitu adanya kehampaan spiritual. Akibatnya, orang akan menjadi stres dan gelisah karena merasa tidak mempunyai pegangan hidup. Untuk alasan ini, Untuk alasan ini, M. Amin Syukur mengarahkan penyelesaian problematika kemodernan ini dengan selalu optimis, berpikir positif, menyandarkan setiap niat dan perbuatan baik hanya untuk ibadah kepada Allah dan berbagi (solidaritas untuk sesama makhluk ciptaan Allah. Selain itu, ia juga menganjurkan untuk selalu ingat (al-dzikr kepada Allah bagaimana pun, kapan pun, dan dimana pun. Mengingat Allah dapat menenangkan

  19. Review of the Monograph of Zardyhan Qinayatuly Kazak State and Jochi Khan» »

    Directory of Open Access Journals (Sweden)

    Zh.M. Sabitov

    2015-09-01

    Full Text Available Research monograph of Zardykhan Qinayatuly “Qazaq memleketі zhane Zhoshy khan” (“Kazakh State and Jochi Khan” was published in the Kazakh language in 2014 in Kazakhstan. There are very few studies in Kazakhstan pub- lished in the Kazakh language on the Golden Horde history. Most historians wri- ting in Russian and English about the Golden Horde history are not familiar with research literature published in other languages. In this review, we note the fol- lowing errors of the author: 1. Purely grammatical errors when writing the names of the historians engaged in all aspects of the history of the ulus of Jochi. 2. Negligence in the design of the monograph, which often do not bear the full output of books and articles that are referenced by the author, neither there is a single list of references at the end of the monograph. 3. Fantastic map of the ulus of Jochi, which contains a lot of factual errors. 4. Ignorance of the historiography of modern research of the ulus of Jochi. From this derive such errors as: naming Jochi with the title of khan, while he was not a khan; confusion with the localiza- tion of the Ak Horde and Kok Horde; ignorance of the fact that Abul Khair Khan became khan only in 1430; uncritical confidence in such unreliable source as Natanzi; improper and unreasoned periodization of the history of the Eastern part of the ulus of Jochi; ignorance of the fact that Berke did not come to power in 1257 but a little later; ignorance of the name of khan Tuda-Mengu when listing the Golden Horde khans; errors in compiling genealogies of the Jochids; incorrect genealogy of the Golden Horde khan Kutlug Timur and his descendants; erro- neous etymology of the ethnonym “Kazak” by attributing to it the origin from the ancient Saks; numerous errors in the chronology of the eastern part of the ulus of Jochi; pseudoscientific etymology of the origin of the term Juz from the ancient Xiongnu as well as pseudoscientific attempt to find

  20. KÜRESELLEŞME SÜRECİNDE TARIM KOOPERATİFLERİ VE KÜRESELLEŞMENİN TARIM KOOPERATİFLERİNE ETKİSİ

    OpenAIRE

    SERİNİKLİ, Nilüfer; İNAN, İ Hakkı

    2011-01-01

    Küreselleşme; ülke sınırlarının olmadığı, emeğin, sermayenin, insanların, üretim faktörlerinin, malların ve hizmetlerin sınır tanımadan dolaşmasıdır. Sınırların ortadan kalkması, ulusal ve uluslararası mal ve hizmet piyasalarında rekabeti arttırmıştır. Artan rekabet tüm sektörleri etkilediği gibi kooperatifleri de etkilemiştir. Böylece, birçok ülkedeki kooperatifler küreselleşmenin yarattığı fırsatlardan yararlanmak ve sakıncalarını en aza indirmek amacıyla yatay ve dikey bütünleşme yoluna gi...

  1. Projekts Sporta kluba izveidošanai

    OpenAIRE

    Andrejevs, Jurijs

    2010-01-01

    Maģistra darba temats ir „PROJEKTS SPORTA KLUBA „URBAN GYM” IZVEIDOŠANA.” Uzņēmējdarbības vide Latvijā pēdējos gados sākusi stipri vien mainīties. No vienas puses, tā lēnām kļūst sakārtotāka, no otras puses, iezīmējas arvien lielāks konkurences pieaugums. Tirgus tiek piesātināts, un aizvien grūtāk kļūst darboties, nedomājot par konkurenci, darbības aktivitāti un rentabilitāti. Vadītājiem un īpašniekiem nemitīgi jādomā, ar ko uzņēmums īsti pelna naudu, kā varētu pelnīt vairāk. Bet neskatoti...

  2. Kultur, privatliv og offentlighet: Religionens plass i det sekulariserte samfunnet

    Directory of Open Access Journals (Sweden)

    Bjørn Myskja

    2009-05-01

    Full Text Available Den dominerende oppfatningen i den politiske og moralfilosofiske tenkningen de siste tiår har vært at religion ikke bør spille noen avgjørende politisk rolle i det moderne sekulariserte demokrati. Religion tilhører privatsfæren, og politiske avgjørelser må fattes på et felles grunnlag, uavhengig av livssyn. De mest sentrale tenkerne i vår tids politiske filosofi, John Rawls og Jürgen Habermas, har begge i tidlige arbeider gitt uttrykk for at dette er en oppfatning som vil få en allmenn, global tilslutning, for de ser modernisering og sekularisering som to sider av samme sak. Det er nærmest to uunngåelige fenomen ettersom globalisering og modernisering vil føre til svekkelse av tradisjonelle kulturer og utbredelse av individualisme og demokratiske idealer. Bakgrunnen for dette temanummeret er at en rekke erfaringer fra de siste tiår har ledet til en gjenåpning av spørsmålet om religionens plass i sekulariserte samfunn.http://dx.doi.org/10.5324/eip.v3i1.1706

  3. Analysis of n-gram based promoter recognition methods and application to whole genome promoter prediction.

    Science.gov (United States)

    Rani, T Sobha; Bapi, Raju S

    2009-01-01

    Promoter prediction is an important and complex problem. Pattern recognition algorithms typically require features that could capture this complexity. A special bias towards certain combinations of base pairs in the promoter sequences may be possible. In order to determine these biases n-grams are usually extracted and analyzed. An n-gram is a selection of n contiguous characters from a given character stream, DNA sequence segments in this case. Here a systematic study is made to discover the efficacy of n-grams for n = 2, 3, 4, 5 in promoter prediction. A study of n-grams as features for a neural network classifier for E. coli and Drosophila promoters is made. In case of E. coli n=3 and in case of Drosophila n=4 seem to give optimal prediction values. Using the 3-gram features, promoter prediction in the genome sequence of E. coli is done. The results are encouraging in positive identification of promoters in the genome compared to software packages such as BPROM, NNPP, and SAK. Whole genome promoter prediction in Drosophila genome was also performed but with 4-gram features.

  4. Augmenting the activity of antifungal agents against aspergilli using structural analogues of benzoic acid as chemosensitizing agents.

    Science.gov (United States)

    Kim, Jong H; Campbell, Bruce C; Mahoney, Noreen; Chan, Kathleen L; Molyneux, Russell J; Balajee, Arunmozhi

    2010-10-01

    A number of benzoic acid analogues showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. Structure-activity analysis revealed that antifungal activities of benzoic and gallic acids were increased by addition of a methyl, methoxyl or chloro group at position 4 of the aromatic ring, or by esterification of the carboxylic acid with an alkyl group, respectively. Thymol, a natural phenolic compound, was a potent chemosensitizing agent when co-applied with the antifungal azole drugs fluconazole and ketoconazole. The thymol-azole drug combination demonstrated complete inhibition of fungal growth at dosages far lower than the drugs alone. Co-application of thymol with amphotericin B had an additive effect on all strains of aspergilli tested with the exception of two of three strains of A. terreus, where there was an antagonistic effect. Use of two mitogen-activated protein kinase (MAPK) mutants of A. fumigatus, sakAΔ and mpkCΔ, having gene deletions in the oxidative stress response pathway, indicated antifungal and/or chemosensitization activity of the benzo analogues was by disruption of the oxidative stress response system. Results showed that both these genes play overlapping roles in the MAPK system in this fungus. The potential of safe, natural compounds or analogues to serve as chemosensitizing agents to enhance efficacy of commercial antifungal agents is discussed. Published by Elsevier Ltd.

  5. Celmeņu Armillaria spp. dzīvotspēja un patogenitāte Latvijas izcelsmes priežu Pinus sylvestris un egļu Picea abies stādos

    OpenAIRE

    Lukstiņa, Liene Dārta

    2017-01-01

    Celmeņu Armillaria spp. ģints sēņu izraisītā sakņu trupe ir iemesls ievērojamiem mežsaimnieciskajiem zaudējumiem. Darbā analizēta Armillaria solidipes, A. cepistipes un A. borealis dzīvotspēja, izplatīšanās potenciāls un patogenitāte 5-6 gadus vecos parasto priežu (563 gab.) un parasto egļu (350 gab.) stādos. Armillaria spp. inokulātu attīstība novērota stādu audzēšanai paredzētajā kūdras substrātā. Novērojumus priežu un egļu stādiem veica pēc attiecīgi 12 un 15 mēnešiem. Patogēna dzīvotspēja...

  6. A key centriole assembly interaction interface between human PLK4 and STIL appears to not be conserved in flies

    Directory of Open Access Journals (Sweden)

    Matthew A. Cottee

    2017-03-01

    Full Text Available A small number of proteins form a conserved pathway of centriole duplication. In humans and flies, the binding of PLK4/Sak to STIL/Ana2 initiates daughter centriole assembly. In humans, this interaction is mediated by an interaction between the Polo-Box-3 (PB3 domain of PLK4 and the coiled-coil domain of STIL (HsCCD. We showed previously that the Drosophila Ana2 coiled-coil domain (DmCCD is essential for centriole assembly, but it forms a tight parallel tetramer in vitro that likely precludes an interaction with PB3. Here, we show that the isolated HsCCD and HsPB3 domains form a mixture of homo-multimers in vitro, but these readily dissociate when mixed to form the previously described 1:1 HsCCD:HsPB3 complex. In contrast, although Drosophila PB3 (DmPB3 adopts a canonical polo-box fold, it does not detectably interact with DmCCD in vitro. Thus, surprisingly, a key centriole assembly interaction interface appears to differ between humans and flies.

  7. Identification of virulence genes carried by bacteriophages obtained from clinically isolated methicillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    Karasartova, Djursun; Cavusoglu, Zeynep Burcin; Turegun, Buse; Ozsan, Murat T; Şahin, Fikret

    2016-12-01

    Bacteriophages play an important role in the pathogenicity of Staphylococcus aureus (S. aureus) either by carrying accessory virulence factors or several superantigens. Despite their importance, there are not many studies showing the actual distribution of the virulence genes carried by the prophages obtained from the clinically isolated Staphylococcus. In this study, we investigated prophages obtained from methicillin-resistant S. aureus (MRSA) strains isolated from hospital- and community-associated (HA-CA) infections for the virulence factors. In the study, 43 phages isolated from 48 MRSA were investigated for carrying toxin genes including the sak, eta, lukF-PV, sea, selp, sek, seg, seq chp, and scn virulence genes using polymerase chain reaction (PCR) and Southern blot. Restriction fragment length polymorphism was used to analyze phage genomes to investigate the relationship between the phage profiles and the toxin genes' presence. MRSA strains isolated from HA infections tended to have higher prophage presence than the MRSA strains obtained from the CA infections (97% and 67%, respectively). The study showed that all the phages with the exception of one phage contained one or more virulence genes in their genomes with different combinations. The most common toxin genes found were sea (83%) followed by sek (77%) and seq (64%). The study indicates that prophages encode a significant proportion of MRSA virulence factors.

  8. Elma Suyunun Sıcak Teknikle Durultulması İçin Yeni bir Yöntem

    Directory of Open Access Journals (Sweden)

    Aziz Ekşi

    2015-02-01

    Full Text Available Elma suyunun konsantreye işlenmesinde üretim tekniği ve ekonomik açıdan önemli üstünlükleri olan yeni bir sıcak durultma tekniği tanımlanmıştır. Yeni bir amilaz ile pektin ve nişastanın 45-50 oC de parçalanması pektinazla ortaklaşa sağlanmaktadır. Bunu izleyen durultma işleminde de sıcaklık 45-50 oC de kalmaktadır. Bentonit, jelatin ve kieselsol katılması ile durulma sağlanmaktadır. Daha hızlı ve yeterli topaklaşma ve çökme işleme süresini kısaltmaktadır. Mikrobiyolojik bulaşma sakıncası da, durultma sıcaklığının 45-50 oC olması ile azalmış olmaktadır.

  9. Regular Nanoscale Protein Patterns via Directed Adsorption through Self-Assembled DNA Origami Masks.

    Science.gov (United States)

    Ramakrishnan, Saminathan; Subramaniam, Sivaraman; Stewart, A Francis; Grundmeier, Guido; Keller, Adrian

    2016-11-16

    DNA origami has become a widely used method for synthesizing well-defined nanostructures with promising applications in various areas of nanotechnology, biophysics, and medicine. Recently, the possibility to transfer the shape of single DNA origami nanostructures into different materials via molecular lithography approaches has received growing interest due to the great structural control provided by the DNA origami technique. Here, we use ordered monolayers of DNA origami nanostructures with internal cavities on mica surfaces as molecular lithography masks for the fabrication of regular protein patterns over large surface areas. Exposure of the masked sample surface to negatively charged proteins results in the directed adsorption of the proteins onto the exposed surface areas in the holes of the mask. By controlling the buffer and adsorption conditions, the protein coverage of the exposed areas can be varied from single proteins to densely packed monolayers. To demonstrate the versatility of this approach, regular nanopatterns of four different proteins are fabricated: the single-strand annealing proteins Redβ and Sak, the iron-storage protein ferritin, and the blood protein bovine serum albumin (BSA). We furthermore demonstrate the desorption of the DNA origami mask after directed protein adsorption, which may enable the fabrication of hierarchical patterns composed of different protein species. Because selectivity in adsorption is achieved by electrostatic interactions between the proteins and the exposed surface areas, this approach may enable also the large-scale patterning of other charged molecular species or even nanoparticles.

  10. KAJIAN TERHADAP BEBERAPA METODE PENYUSUTAN DAN PENGARUHNYA TERHADAP PERHITUNGAN BEBAN POKOK PENJUALAN (COST OF GOOD SOLD

    Directory of Open Access Journals (Sweden)

    Juniady Slamed Setiawan

    2001-01-01

    Full Text Available Every company must generate financial statement, that provide information about income, changes in financial position to whom that concerned. In preparing financial statement, each company has a power to choose the accounting methods and technics that recommended by Financial Accounting Standard. Accounting policies adopted by firm has a substanstial impact in financial statement.Therefore the company that has equal performance will report different result.This article try to present the impact of choosing depreciation method in calculating cost of goods sold. Abstract in Bahasa Indonesia : Setiap perusahaan wajib menerbitkan laporan keuangan, yang memberikan informasi mengenai hasil usaha, perubahan posisi keuangan kepada pihak yang memerlukan. Dalam menyusun laporan keuangan, perusahaan memiliki keleluasaan untuk memilih metode dan teknik sepanjang metode yang dipilih tersebut ada dalam SAK (Standar Akuntansi Keuangan. Pemilihan metode akuntansi memiliki dampak yang sangat besar terhadap laporan keuangan yang dihasilkan. Dengan demikian dimungkinkan perusahaan yang sebenarnya memiliki kinerja yang sama dapat melaporkan hasil yang berbeda. Tulisan ini mencoba untuk mengetengahkan dampak pemilihan metode penyusutan terhadap perhitungan beban pokok penjualan (cost of goods sold. Kata kunci: metode penyusutan, beban penyusutan, aktiva tetap, beban pokok penjualan.

  11. Rare occurrence of methicillin-resistant Staphylococcus aureus CC130 with a novel mecA homologue in humans in Germany.

    Directory of Open Access Journals (Sweden)

    Christiane Cuny

    Full Text Available MRSA CC130 containing the mecA homologue mecA(LGA251 were reported from the UK and from Denmark so far from cattle and humans. Here we report on 11 MRSA CC130 among a sample of 12691 isolates of human origin collected from January 2006 until June 2011. MRSA CC130 grew insufficiently on chromogernic agar plates for detection of MRSA; the agglutination test for presence of PBP2a was negative. We designed primers for specific detection of mecA(LGA251 as well as for concomitant detection of both, mec(LGA251 and mecA. As already described, the isolates exhibited spa-types t843, t1736, and t1773. The ccrA homologue indicated the presence SCCmec(XI. When subjected to further characterization by means of a commercially available microarray the isolates were negative for sak chp, and scn, and as expected positive for hla, untruncated hlb, and hld. They furthermore contained edinB, aur, slpA, slpB, slpE. From genes coding for surface and cell wall associated products the ica-operon, cap8, clfA, clfF, ebpS, fnbA, fnbB, sdrC were detected but not cna. The isolates were negative for enterotoxin genes and tst, as well as for eta, and etb; agr-type was III.

  12. Search for Majorana neutrinos with the first two years of EXO-200 data.

    Science.gov (United States)

    2014-06-12

    Many extensions of the standard model of particle physics suggest that neutrinos should be Majorana-type fermions-that is, that neutrinos are their own anti-particles-but this assumption is difficult to confirm. Observation of neutrinoless double-β decay (0νββ), a spontaneous transition that may occur in several candidate nuclei, would verify the Majorana nature of the neutrino and constrain the absolute scale of the neutrino mass spectrum. Recent searches carried out with (76)Ge (the GERDA experiment) and (136)Xe (the KamLAND-Zen and EXO (Enriched Xenon Observatory)-200 experiments) have established the lifetime of this decay to be longer than 10(25) years, corresponding to a limit on the neutrino mass of 0.2-0.4 electronvolts. Here we report new results from EXO-200 based on a large (136)Xe exposure that represents an almost fourfold increase from our earlier published data sets. We have improved the detector resolution and revised the data analysis. The half-life sensitivity we obtain is 1.9 × 10(25) years, an improvement by a factor of 2.7 on previous EXO-200 results. We find no statistically significant evidence for 0νββ decay and set a half-life limit of 1.1 × 10(25) years at the 90 per cent confidence level. The high sensitivity holds promise for further running of the EXO-200 detector and future 0νββ decay searches with an improved Xe-based experiment, nEXO.

  13. Correlation of endoscopic severity of gastroesophageal reflux disease (gerd) with body mass index (bmi)

    International Nuclear Information System (INIS)

    Zafar, S.; Haq, I.U.; Butt, A.R.; Shafiq, F.; Huda, G.; Mirza, G.; Rehman, A.U.

    2007-01-01

    To assess the correlation of endoscopic severity of Gastroesophageal Reflux Disease (GERD) with Body Mass Index (BMI). This study was conducted on 203 patients, who presented with upper GI symptoms. Patients who fulfilled the symptom criteria were referred for endoscopy. Classification of GERD was done according to LA Grading classification system. Body mass index (BMI) was calculated as Body Weight (BW) in kilograms (kg) divided by the square of the body height (BH) in meter (m2). Patient data was analyzed using SPSS 12 software. Statistical evaluation was done using non-parametric Wilcoxon's-sign Rank test. P-value <0.05 was considered to be statistically significant. Distribution of GERD was as follows: GERD-A subjects 65 (32%), GERD B subjects 72 (35.4%), GERD-C subjects 23 (11.3%), GERD-D subjects 10 (4.92%), while Non-Erosive Reflux Disease (NERD) was present in 33 subjects (16.2%). Mean BMI was 27+5.02SD (range of 18.2-38.3). BMI of patients having NERD was in normal range but patients who were having advanced disease i.e. Grade C-D were in obese range of BMI, while those who were having LA grade A-B were in overweight BMI range. When regrouped as mild GERD (grade A-B) and NERD versus severe GERD (grade C-D), there was a strong significant correlation between severity of GERD and BMI, as detected by Wilcoxon's signed Rank test (p=0.001). Higher BMI seems to be associated with higher degree of endoscopic GERD severity. (author)

  14. Eradication of tephritid fruit fly pest populations: outcomes and prospects

    International Nuclear Information System (INIS)

    Suckling, David Maxwell; Kean, John M.; Stringer, Lloyd D.; Cáceres-Barrios, Carlos; Hendrichs, Jorge; Reyes-Flores, Jesus; Dominiak, Bernard C.

    2015-01-01

    BACKGROUND: The number of insect eradication programmes is rising in response to globalisation. A database of arthropod and plant pathogen eradications covers 1050 incursion responses, with 928 eradication programmes on 299 pest and disease taxa in 104 countries (global eradication database b3.net.nz/gerda). METHODS: A subset of the database was assembled with 211 eradication or response programmes against 17 species of fruit flies (Tephritidae) in 31 countries, in order to investigate factors affecting the outcome. RESULTS: The failure rate for fruit fly eradication programmes was about 7%, with 0% for Ceratitis capitata (n=85 programmes) and 0% for two Anastrepha species (n=12 programmes), but 12% for 13 Bactrocera species (n=108 programmes). A number of intended eradication programmesagainst long-established populations were not initiated because of cost and other considerations, or evolved during the planning phase into suppression programmes. Cost was dependent on area, ranged from $US 0.1 million to $US 240 million and averaged about $US 12 million (normalised to $US in 2012). In addition to the routine use of surveillance networks, quarantine and fruit destruction, the key tactics used in eradication programmes were male annihilation, protein bait sprays (which can attract both sexes), fruit destruction and the sterile insect technique. CONCLUSIONS: Eradication success generally required the combination of several tactics applied on an area-wide basis. Because the likelihood of eradication declines with an increase in the area infested, it pays to invest in effective surveillance networks that allow early detection and delimitation while invading populations are small, thereby greatly favouring eradication success. (author)

  15. The GALATEA test facility and a first study of α-induced surface events in a germanium detector

    International Nuclear Information System (INIS)

    Irlbeck, Sabine

    2014-01-01

    Germanium detectors are a choice technology in fundamental research. They are suitable for the search for rare events due to their high sensitivity and excellent energy resolution. As an example, the GERDA (GERmanium Detector Array) experiment searching for neutrinoless double beta decay is described. The observation of this decay would resolve the fundamental question whether the neutrino is its own antiparticle. Especially adapted detector technologies and low background rates needed to detect very rare events such as neutrinoless double beta decays are discussed. The identification of backgrounds originating from the interaction of radiation, especially α-particles, is a focus of this thesis. Low background experiments face problems from α-particles due to unavoidable surface contaminations of the germanium detectors. The segmentation of detectors is used to obtain information about the special characteristics of selected events. The high precision test stand GALATEA was especially designed for surface scans of germanium detectors. As part of this work, GALATEA was completed and commissioned. The final commissioning required major upgrades of the original design which are described in detail. Collimator studies with two commercial germanium detectors are presented. Different collimation levels for a β-source were investigated and crystal axis effects were examined. The first scan with an α-source of the passivated end-plate of a special 19-fold segmented prototype detector mounted in GALATEA is described. The α-induced surface events were studied and characterized. Crosstalk and mirror pulses seen in the segments of the germanium detector were analyzed. The detector studies presented in this thesis will help to further improve the design of germanium detectors for low background experiments.

  16. Eradication of tephritid fruit fly pest populations: outcomes and prospects.

    Science.gov (United States)

    Suckling, David Maxwell; Kean, John M; Stringer, Lloyd D; Cáceres-Barrios, Carlos; Hendrichs, Jorge; Reyes-Flores, Jesus; Dominiak, Bernard C

    2016-03-01

    The number of insect eradication programmes is rising in response to globalisation. A database of arthropod and plant pathogen eradications covers 1050 incursion responses, with 928 eradication programmes on 299 pest and disease taxa in 104 countries (global eradication database b3.net.nz/gerda). A subset of the database was assembled with 211 eradication or response programmes against 17 species of fruit flies (Tephritidae) in 31 countries, in order to investigate factors affecting the outcome. The failure rate for fruit fly eradication programmes was about 7%, with 0% for Ceratitis capitata (n = 85 programmes) and 0% for two Anastrepha species (n = 12 programmes), but 12% for 13 Bactrocera species (n = 108 programmes). A number of intended eradication programmes against long-established populations were not initiated because of cost and other considerations, or evolved during the planning phase into suppression programmes. Cost was dependent on area, ranged from $US 0.1 million to $US 240 million and averaged about $US 12 million (normalised to $US in 2012). In addition to the routine use of surveillance networks, quarantine and fruit destruction, the key tactics used in eradication programmes were male annihilation, protein bait sprays (which can attract both sexes), fruit destruction and the sterile insect technique. Eradication success generally required the combination of several tactics applied on an area-wide basis. Because the likelihood of eradication declines with an increase in the area infested, it pays to invest in effective surveillance networks that allow early detection and delimitation while invading populations are small, thereby greatly favouring eradication success. © 2014 Society of Chemical Industry.

  17. Contact allergies in haemodialysis patients: a prospective study of 75 patients.

    Science.gov (United States)

    Gaudy-Marqueste, C; Jouhet, C; Castelain, M; Brunet, P; Berland, Y; Grob, J J; Richard, M A

    2009-02-01

    Haemodialysis exposes patients to many potentially sensitizing allergens. The primary objective of this study was to evaluate the prevalence of delayed hypersensitivity in a population of haemodialysis patients. Secondary objectives were to identify the possible risk factors for contact sensitization and to propose a series of skin tests adapted to haemodialysis patients. A prospective monocentric study was carried out in a nonselected population of haemodialysis patients. For each patient, medical history of atopy and allergic contact dermatitis, ongoing treatments (including topical ones), presence of eczema at the site of vascular access for haemodialysis were recorded. Allergological investigation included delayed hypersensitivity tests (European Environmental and Contact Dermatitis Research Group battery, tests GERDA, additional list and a battery of antiseptics and other dialysis-specific allergens) and latex skin prick test. Seventy-five patients (41 men, 34 women, mean age of 65 years old), with a mean 3.8 years under dialysis, were included. Nineteen patients (25%) had at least one positive skin test and 13 (17%) a positive patch test to at least one allergen relative to dialysis process including eight tests to lidocaine-prilocaine cream and three to povidone-iodine. Tests results seemed clinically relevant since nine patients had localized pruritus at the fistula site and six patients active eczema around it. Contact sensitizations are frequent in haemodialysis patients and are linked to vascular access conditioning especially the use of lidocaine-prilocaine cream. Designing a specific test battery could help to diagnose the potential allergens and subsequently to give advice to avoid contact with sensitizing agents.

  18. Fraunhofer Institut fuer Molekularbiologie und Angewandte Oekologie (IME). Annual report 2014/2015; Fraunhofer Institut fuer Molekularbiologie und Angewandte Oekologie (IME). Jahresbericht 2014/2015

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2015-07-01

    The Annual report 2014/2015 of the Fraunhofer Institute for molecular biology and applied ecology includes the following contributions: (A) Molecular Biology: TheraSECOURE - Novel immunotherapeutics for targeted cancer therapy; ''MultiNaBel ''- Automated diagnosis of leukemia; Breeding potato for optimized specialty starches; NGS-based zygosity detection in transgenic maize; High-throughput screen ing system for cellulases based on microfluidic devices; Filter aids reduce production costs for plant-derived biopharmaceuticals; Transient expression of recombinant proteins in packed plant cells; ERA-NET Biodiversa EXOTIC project on the invasive harlequin ladybird; AIM-Biotech supported by the Fraunhofer-Max Planck Cooperation program; Metabolic control analysis of the MEP pathway; Metabolic engineering of Clostridium spp. by genomic integration; The Fraunhofer Future Foundation malaria project; Autoantibodies to type 11 collagen as biomarkers of rheumatoid arthritis; Development of a new drug for the treatment of sepsis; Databionic drug research; Structure-based drug design; Neu{sup 2}: competence consortium for multiple sclerosis drug development; Natural compounds from marine fungi for the treatment of cancer; FCR Center for Systems Biotechnology (CSB): Two selected projects; Development and implementation of a plant-derived vaccine against yellow fever. (B) Applied Ecology: Comparison and improvement of laboratory water/sediment test systems; Inter-laboratory comparison of Hyalella Azteca exposure tests lasting 10-42 days; Substance- and matrix-related environmental monitoring of biocides; GERDA-geobased runoff, erosion and drainage risk assessment; The minimum detectable difference and reliability of mesocosm studies; Mechanistic effect models for the ecological risk assessment of pesticides; Molecular biology test for the online analysis of spontaneously-fermented wines; Coupling two test systems to determine the effect of wastewater

  19. Fraunhofer Institut fuer Molekularbiologie und Angewandte Oekologie (IME). Annual report 2014/2015

    International Nuclear Information System (INIS)

    2015-01-01

    The Annual report 2014/2015 of the Fraunhofer Institute for molecular biology and applied ecology includes the following contributions: (A) Molecular Biology: TheraSECOURE - Novel immunotherapeutics for targeted cancer therapy; ''MultiNaBel ''- Automated diagnosis of leukemia; Breeding potato for optimized specialty starches; NGS-based zygosity detection in transgenic maize; High-throughput screen ing system for cellulases based on microfluidic devices; Filter aids reduce production costs for plant-derived biopharmaceuticals; Transient expression of recombinant proteins in packed plant cells; ERA-NET Biodiversa EXOTIC project on the invasive harlequin ladybird; AIM-Biotech supported by the Fraunhofer-Max Planck Cooperation program; Metabolic control analysis of the MEP pathway; Metabolic engineering of Clostridium spp. by genomic integration; The Fraunhofer Future Foundation malaria project; Autoantibodies to type 11 collagen as biomarkers of rheumatoid arthritis; Development of a new drug for the treatment of sepsis; Databionic drug research; Structure-based drug design; Neu 2 : competence consortium for multiple sclerosis drug development; Natural compounds from marine fungi for the treatment of cancer; FCR Center for Systems Biotechnology (CSB): Two selected projects; Development and implementation of a plant-derived vaccine against yellow fever. (B) Applied Ecology: Comparison and improvement of laboratory water/sediment test systems; Inter-laboratory comparison of Hyalella Azteca exposure tests lasting 10-42 days; Substance- and matrix-related environmental monitoring of biocides; GERDA-geobased runoff, erosion and drainage risk assessment; The minimum detectable difference and reliability of mesocosm studies; Mechanistic effect models for the ecological risk assessment of pesticides; Molecular biology test for the online analysis of spontaneously-fermented wines; Coupling two test systems to determine the effect of wastewater

  20. DEVELOPMENT OF SHALLOW VISCOUS OIL RESERVES IN NORTH SLOPE

    Energy Technology Data Exchange (ETDEWEB)

    Kishore K. Mohanty

    2004-12-01

    North Slope of Alaska has huge oil deposits in heavy oil reservoirs such as Ugnu, West Sak and Shrader Bluff etc. The viscosity of the last two reservoir oils vary from {approx}30 cp to {approx}3000 cp and the amount in the range of 10-20 billion barrels. High oil viscosity and low formation strength impose problems to high recovery and well productivity. Water-alternate-gas injection processes can be effective for the lower viscosity end of these deposits in West Sak and Shrader Bluff. Several gas streams are available in the North Slope containing NGL and CO{sub 2} (a greenhouse gas). The goal of this research is to develop tools to find optimum solvent, injection schedule and well-architecture for a WAG process in North Slope shallow sand viscous oil reservoirs. Coreflood, quarter 5-spot study, compositional simulation, wettability, relative permeability study and streamline-based simulation were conducted in this project. 1D compositional simulation results agree reasonably well with those of the slim tube experiments. Injection of CO{sub 2}-NGL is preferable over that of PBG-NGL. MME is sensitive to pressure (in the range of 1300-1800 psi) for the injection of PBG-NGL, but not for CO{sub 2}-NGL. Three hydrocarbon phases form in this pressure range. As the mean thickness of the adsorbed organic layer on minerals increases, the oil-water contact angle increases. The adsorbed organic films left behind after extraction of oil by common aromatic solvents used in core studies, such as toluene and decalin, are thinner than those left behind by non-aromatic solvents, such as cyclohexane. The force of adhesion for minerals aged with just the asphaltene fraction is similar to that of the whole oil implying that asphaltenes are responsible for the mixed-wettability in this reservoir. A new relative permeability model for a four-phase, mixed-wet system has been proposed. A streamline module is developed which can be incorporated in an existing finite-difference based

  1. Pathogenic Characteristics of Staphylococcus aureus Endovascular Infection Isolates from Different Clonal Complexes

    Directory of Open Access Journals (Sweden)

    Dafne Pérez-Montarelo

    2017-05-01

    Full Text Available Staphylococcus aureus is a major cause of bacteremia and, even with appropriate clinical management, causes high morbidity, and mortality due to its involvement in endovascular complications and metastatic infections. Through different pathogenic in vivo and in vitro models we investigated the behavior of S. aureus most relevant clonal complexes (CCs causing endovascular complications. We analyzed 14 S. aureus strains representing CC5, CC8, CC15, CC30, and CC45 that caused endovascular complications, including methicillin susceptible and resistant isolates and strains with different functionality of the agr global regulator. Their adherence to collagen, interaction with the endothelium, resistance to immune attack, capacity to form biofilm and virulence in the Galleria mellonella model were analyzed. CC30 and CC45 showed greater adhesion to collagen and CC8 showed a trend towards higher rate of intracellular persistence in endothelial cells. All CCs exhibited similar tolerance to neutrophil antimicrobial peptide hNP-1 and were capable of forming biofilms under static conditions. The virulence assay in the G. mellonella model demonstrated that CC15 and CC30 were the most and least virulent, respectively. The analysis of the genomic sequences of the most relevant virulence genes identified some CC15 specific gene patterns (absence of enterotoxins and sak gene and variants (mainly in leucocidins and proteases, but did not reveal any gene or variant that could be responsible for the increased virulence detected for CC15 strains. Even though all the CCs were capable of causing endovascular complications, our results showed that different CCs are likely to produce these complications through different mechanisms which, if confirmed in more sophisticated models, would indicate the need to more specific management and therapeutic approaches.

  2. BİLEZİKLİ ASENKRON MAKİNELERDE ANLIK YÜKSEK MOMENT VE HIZ DENETİMİ İÇİN ROTOR DEVRESİNE BULANIK MANTIK TABANLI GÜÇ ENJEKSİYONU

    Directory of Open Access Journals (Sweden)

    Selami KESLER

    2009-01-01

    Full Text Available Büyük güç gerektiren uygulamalarda yüksek moment üretimi ve rüzgâr santrallerinde sabit frekanslı sabit güç üretimi için kullanılan bilezikli asenkron makinelerde rotor devresi güç akışı farklı yöntemlerle denetlenir. Denetimli yüksek moment üretmek, en uygun güç katsayısı elde etmek ve hız denetimi için rotor devresine bilezikler üzerinden kayma frekanslı gerilim uygulanabilir. Bu çalışmada, öncelikle bilezikli bir asenkron makinede rotor sargılarına bilezikler üzerinden gerilim uygulanmasının dinamik etkileri araştırılmış ve yöntemin sakıncalı yönleri uygulama desteğiyle ortaya konulmuştur. Daha sonra bu dinamik etkileri iyileştirmek üzere, makinenin anlık zorlanmalarda yüksek moment üretimini denetlemek ve hızını ayarlamak için rotor tarafında bulanık mantık denetleyicili bir evirici modeli önerilmiştir. Sürekli çalışma durumunda stator sargıları doğrudan şebekeye bağlı olan sistemin benzetim modeli için C/C++ programı geliştirilmiş ve farklı yük şartları için elde edilen sonuçlar tartışılmıştır.

  3. Impact of beliefs about pain control on perceptions of illness in surgical patients

    Directory of Open Access Journals (Sweden)

    Jaroslaw Jerzy Sak

    2015-12-01

    Full Text Available [b][/b][b]Objectives.[/b] Adequacy of pain management in surgical patients is a major contributor to overall treatment outcomes and positive illness perceptions. However, it may be subjectively predetermined by a patient’s beliefs about pain control. This study assesses the relationships between beliefs about pain control and perceptions of illness in thoracic surgical patients. [b]Materials and method.[/b] A total of 135 patients (72 women and 63 men; mean age 58.4±14.25y were enrolled in the questionnaire study based on the Beliefs about Pain Control Questionnaire (BPCQ by S. Skevington and the Multidimensional Essence of Disease and Illness Scale (MEDIS by J. Sak. Analyses were conducted with use of the k-means clustering technique and one-way ANOVA. [b]Results.[/b] Applied classification revealed 3 different clusters of patients with regard to their beliefs about pain control: 1 weak, undifferentiated pain control; 2 intensified influence of chance pain control; 3 strong undifferentiated pain control. Significant differences in illness perceptions between clusters were disclosed in 3 MEDIS dimensions: self-realization constraints (F=4.70; p=0.01; 1 vs. 3, mental dysfunction (F=3.44, p=0.04; 1 vs. 3 and physical dysfunction (F=3.10, p=0.05; 1 vs 2. Patients in cluster 3 demonstrated a greater feeling of self-realization constraints and mental dysfunction than in cluster 1, whereas patients in cluster 2 perceived physical dysfunction as a greater distress than those in cluster 1. [b]Conclusions.[/b] Beliefs about pain control significantly influence illness perceptions, and thus may affect the results of treatment in surgical patients. Psychological modelling of beliefs about pain control may offer a valuable way to improve overall clinical outcomes.

  4. Livestock-Associated Methicillin Resistant and Methicillin Susceptible Staphylococcus aureus Sequence Type (CC)1 in European Farmed Animals: High Genetic Relatedness of Isolates from Italian Cattle Herds and Humans.

    Science.gov (United States)

    Alba, Patricia; Feltrin, Fabiola; Cordaro, Gessica; Porrero, María Concepción; Kraushaar, Britta; Argudín, María Angeles; Nykäsenoja, Suvi; Monaco, Monica; Stegger, Marc; Aarestrup, Frank M; Butaye, Patrick; Franco, Alessia; Battisti, Antonio

    2015-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) Sequence Type (ST)1, Clonal Complex(CC)1, SCCmec V is one of the major Livestock-Associated (LA-) lineages in pig farming industry in Italy and is associated with pigs in other European countries. Recently, it has been increasingly detected in Italian dairy cattle herds. The aim of this study was to analyse the differences between ST1 MRSA and methicillin-susceptible S. aureus (MSSA) from cattle and pig herds in Italy and Europe and human isolates. Sixty-tree animal isolates from different holdings and 20 human isolates were characterized by pulsed-field gel electrophoresis (PFGE), spa-typing, SCCmec typing, and by micro-array analysis for several virulence, antimicrobial resistance, and strain/host-specific marker genes. Three major PFGE clusters were detected. The bovine isolates shared a high (≥90% to 100%) similarity with human isolates and carried the same SCCmec type IVa. They often showed genetic features typical of human adaptation or present in human-associated CC1: Immune evasion cluster (IEC) genes sak and scn, or sea; sat and aphA3-mediated aminoglycoside resistance. Contrary, typical markers of porcine origin in Italy and Spain, like erm(A) mediated macrolide-lincosamide-streptograminB, and of vga(A)-mediated pleuromutilin resistance were always absent in human and bovine isolates. Most of ST(CC)1 MRSA from dairy cattle were multidrug-resistant and contained virulence and immunomodulatory genes associated with full capability of colonizing humans. As such, these strains may represent a greater human hazard than the porcine strains. The zoonotic capacity of CC1 LA-MRSA from livestock must be taken seriously and measures should be implemented at farm-level to prevent spill-over.

  5. Livestock-Associated Methicillin Resistant and Methicillin Susceptible Staphylococcus aureus Sequence Type (CC1 in European Farmed Animals: High Genetic Relatedness of Isolates from Italian Cattle Herds and Humans.

    Directory of Open Access Journals (Sweden)

    Patricia Alba

    Full Text Available Methicillin-resistant Staphylococcus aureus (MRSA Sequence Type (ST1, Clonal Complex(CC1, SCCmec V is one of the major Livestock-Associated (LA- lineages in pig farming industry in Italy and is associated with pigs in other European countries. Recently, it has been increasingly detected in Italian dairy cattle herds. The aim of this study was to analyse the differences between ST1 MRSA and methicillin-susceptible S. aureus (MSSA from cattle and pig herds in Italy and Europe and human isolates. Sixty-tree animal isolates from different holdings and 20 human isolates were characterized by pulsed-field gel electrophoresis (PFGE, spa-typing, SCCmec typing, and by micro-array analysis for several virulence, antimicrobial resistance, and strain/host-specific marker genes. Three major PFGE clusters were detected. The bovine isolates shared a high (≥90% to 100% similarity with human isolates and carried the same SCCmec type IVa. They often showed genetic features typical of human adaptation or present in human-associated CC1: Immune evasion cluster (IEC genes sak and scn, or sea; sat and aphA3-mediated aminoglycoside resistance. Contrary, typical markers of porcine origin in Italy and Spain, like erm(A mediated macrolide-lincosamide-streptograminB, and of vga(A-mediated pleuromutilin resistance were always absent in human and bovine isolates. Most of ST(CC1 MRSA from dairy cattle were multidrug-resistant and contained virulence and immunomodulatory genes associated with full capability of colonizing humans. As such, these strains may represent a greater human hazard than the porcine strains. The zoonotic capacity of CC1 LA-MRSA from livestock must be taken seriously and measures should be implemented at farm-level to prevent spill-over.

  6. Genetic composition and connectivity of the Antillean manatee (Trichechus manatus manatus) in Panama

    Science.gov (United States)

    Díaz-Ferguson, Edgardo; Hunter, Margaret; Guzmán, Héctor M.

    2017-01-01

    Genetic diversity and haplotype composition of the West Indian manatee (Trichechus manatus) population from the San San Pond Sak wetland in Bocas del Toro, Panama was studied using a segment of mitochondrial DNA (D’loop). No genetic information has been published to date for Panamanian populations. Due to the secretive behavior and small population size of the species in the area, DNA extraction was conducted from opportunistically collected fecal (N=20), carcass tissue (N=4) and bone (N=4) samples. However, after DNA processing only 10 samples provided good quality DNA for sequencing (3 fecal, 4 tissue and 3 bone samples). We found three haplotypes in total; two of these haplotypes are reported for the first time, J02 (N=3) and J03 (N=4), and one J01 was previously published (N=3). Genetic diversity showed similar values to previous studies conducted in other Caribbean regions with moderate values of nucleotide diversity (π= 0.00152) and haplotipic diversity (Hd= 0.57). Connectivity assessment was based on sequence similarity, genetic distance and genetic differentiation between San San population and other manatee populations previously studied. The J01 haplotype found in the Panamanian population is shared with populations in the Caribbean mainland and the Gulf of Mexico showing a reduced differentiation corroborated with Fst value between HSSPS and this region of 0.0094. In contrast, comparisons between our sequences and populations in the Eastern Caribbean (South American populations) and North Western Caribbean showed fewer similarities (Fst =0.049 and 0.058, respectively). These results corroborate previous phylogeographic patterns already established for manatee populations and situate Panamanian populations into the Belize and Mexico cluster. In addition, these findings will be a baseline for future studies and comparisons with manatees in other areas of Panama and Central America. These results should be considered to inform management decisions

  7. Operational Challenges in Gas-To-Liquid (GTL) Transportation Through Trans Alaska Pipeline System (TAPS)

    Energy Technology Data Exchange (ETDEWEB)

    Godwin A. Chukwu; Santanu Khataniar; Shirish Patil; Abhijit Dandekar

    2006-06-30

    Oil production from Alaskan North Slope oil fields has steadily declined. In the near future, ANS crude oil production will decline to such a level (200,000 to 400,000 bbl/day) that maintaining economic operation of the Trans-Alaska Pipeline System (TAPS) will require pumping alternative products through the system. Heavy oil deposits in the West Sak and Ugnu formations are a potential resource, although transporting these products involves addressing important sedimentation issues. One possibility is the use of Gas-to-Liquid (GTL) technology. Estimated recoverable gas reserves of 38 trillion cubic feet (TCF) on the North Slope of Alaska can be converted to liquid with GTL technology and combined with the heavy oils for a product suitable for pipeline transport. Issues that could affect transport of this such products through TAPS include pumpability of GTL and crude oil blends, cold restart of the pipeline following a prolonged winter shutdown, and solids deposition inside the pipeline. This study examined several key fluid properties of GTL, crude oil and four selected blends under TAPS operating conditions. Key measurements included Reid Vapor Pressure, density and viscosity, PVT properties, and solids deposition. Results showed that gel strength is not a significant factor for the ratios of GTL-crude oil blend mixtures (1:1; 1:2; 1:3; 1:4) tested under TAPS cold re-start conditions at temperatures above - 20 F, although Bingham fluid flow characteristics exhibited by the blends at low temperatures indicate high pumping power requirements following prolonged shutdown. Solids deposition is a major concern for all studied blends. For the commingled flow profile studied, decreased throughput can result in increased and more rapid solid deposition along the pipe wall, resulting in more frequent pigging of the pipeline or, if left unchecked, pipeline corrosion.

  8. Staphylococcus aureus innate immune evasion is lineage-specific: a bioinfomatics study.

    Science.gov (United States)

    McCarthy, Alex J; Lindsay, Jodi A

    2013-10-01

    Staphylococcus aureus is a major human pathogen, and is targeted by the host innate immune system. In response, S. aureus genomes encode dozens of secreted proteins that inhibit complement, chemotaxis and neutrophil activation resulting in successful evasion of innate immune responses. These proteins include immune evasion cluster proteins (IEC; Chp, Sak, Scn), staphylococcal superantigen-like proteins (SSLs), phenol soluble modulins (PSMs) and several leukocidins. Biochemical studies have indicated that genetic variants of these proteins can have unique functions. To ascertain the scale of genetic variation in secreted immune evasion proteins, whole genome sequences of 88 S. aureus isolates, representing 25 clonal complex (CC) lineages, in the public domain were analysed across 43 genes encoding 38 secreted innate immune evasion protein complexes. Twenty-three genes were variable, with between 2 and 15 variants, and the variants had lineage-specific distributions. They include genes encoding Eap, Ecb, Efb, Flipr/Flipr-like, Hla, Hld, Hlg, Sbi, Scin-B/C and 13 SSLs. Most of these protein complexes inhibit complement, chemotaxis and neutrophil activation suggesting that isolates from each S. aureus lineage respond to the innate immune system differently. In contrast, protein complexes that lyse neutrophils (LukSF-PVL, LukMF, LukED and PSMs) were highly conserved, but can be carried on mobile genetic elements (MGEs). MGEs also encode proteins with narrow host-specificities arguing that their acquisition has important roles in host/environmental adaptation. In conclusion, this data suggests that each lineage of S. aureus evades host immune responses differently, and that isolates can adapt to new host environments by acquiring MGEs and the immune evasion protein complexes that they encode. Cocktail therapeutics that targets multiple variant proteins may be the most appropriate strategy for controlling S. aureus infections. Copyright © 2013 Elsevier B.V. All rights

  9. Involvement of protein tyrosine phosphatases BcPtpA and BcPtpB in regulation of vegetative development, virulence and multi-stress tolerance in Botrytis cinerea.

    Science.gov (United States)

    Yang, Qianqian; Yu, Fangwei; Yin, Yanni; Ma, Zhonghua

    2013-01-01

    Tyrosine phosphorylation and dephosphorylation have emerged as fundamentally important mechanisms of signal transduction and regulation in eukaryotic cells, governing many processes, but little has been known about their functions in filamentous fungi. In this study, we deleted two putative protein tyrosine phosphatase (PTP) genes (BcPTPA and BcPTPB) in Botrytis cinerea, encoding the orthologs of Saccharomyces cerevisiae Ptp2 and Ptp3, respectively. Although BcPtpA and BcPtpB have opposite functions in conidiation, they are essential for sclerotial formation in B. cinerea. BcPTPA and BcPTPB deletion mutants ΔBcPtpA-10 and ΔBcPtpB-4 showed significantly increased sensitivity to osmotic and oxidative stresses, and to cell wall damaging agents. Inoculation tests showed that both mutants exhibited dramatically decreased virulence on tomato leaves, apples and grapes. In S. cerevisiae, it has been shown that Ptp2 and Ptp3 negatively regulate the high-osmolarity glycerol (HOG) pathway and the cell wall integrity (CWI) pathway. Although both BcPtpA and BcPtpB were able to inactive Hog1 and Mpk1 in S. cerevisiae, in contrast to S. cerevisiae, they positively regulate phosphorylation of BcSak1 (the homologue of Hog1) and BcBmp3 (the homologue of Mpk1) in B. cinerea under stress conditions. These results demonstrated that functions of PTPs in B. cinerea are different from those in S. cerevisiae, and BcPtpA and BcPtpB play important roles in regulation of vegetative development, virulence and in adaptation to oxidative, osmotic and cell-wall damage stresses in B. cinerea.

  10. Involvement of protein tyrosine phosphatases BcPtpA and BcPtpB in regulation of vegetative development, virulence and multi-stress tolerance in Botrytis cinerea.

    Directory of Open Access Journals (Sweden)

    Qianqian Yang

    Full Text Available Tyrosine phosphorylation and dephosphorylation have emerged as fundamentally important mechanisms of signal transduction and regulation in eukaryotic cells, governing many processes, but little has been known about their functions in filamentous fungi. In this study, we deleted two putative protein tyrosine phosphatase (PTP genes (BcPTPA and BcPTPB in Botrytis cinerea, encoding the orthologs of Saccharomyces cerevisiae Ptp2 and Ptp3, respectively. Although BcPtpA and BcPtpB have opposite functions in conidiation, they are essential for sclerotial formation in B. cinerea. BcPTPA and BcPTPB deletion mutants ΔBcPtpA-10 and ΔBcPtpB-4 showed significantly increased sensitivity to osmotic and oxidative stresses, and to cell wall damaging agents. Inoculation tests showed that both mutants exhibited dramatically decreased virulence on tomato leaves, apples and grapes. In S. cerevisiae, it has been shown that Ptp2 and Ptp3 negatively regulate the high-osmolarity glycerol (HOG pathway and the cell wall integrity (CWI pathway. Although both BcPtpA and BcPtpB were able to inactive Hog1 and Mpk1 in S. cerevisiae, in contrast to S. cerevisiae, they positively regulate phosphorylation of BcSak1 (the homologue of Hog1 and BcBmp3 (the homologue of Mpk1 in B. cinerea under stress conditions. These results demonstrated that functions of PTPs in B. cinerea are different from those in S. cerevisiae, and BcPtpA and BcPtpB play important roles in regulation of vegetative development, virulence and in adaptation to oxidative, osmotic and cell-wall damage stresses in B. cinerea.

  11. The Riesz-Radon-Frechet problem of characterization of integrals

    Energy Technology Data Exchange (ETDEWEB)

    Zakharov, Valerii K; Rodionov, Timofey V [M. V. Lomonosov Moscow State University, Moscow (Russian Federation); Mikhalev, Aleksandr V [Centre for New Information Technologies, Moscow State University (Russian Federation)

    2010-11-16

    This paper is a survey of results on characterizing integrals as linear functionals. It starts from the familiar result of F. Riesz (1909) on integral representation of bounded linear functionals by Riemann-Stieltjes integrals on a closed interval, and is directly connected with Radon's famous theorem (1913) on integral representation of bounded linear functionals by Lebesgue integrals on a compact subset of R{sup n}. After the works of Radon, Frechet, and Hausdorff, the problem of characterizing integrals as linear functionals took the particular form of the problem of extending Radon's theorem from R{sup n} to more general topological spaces with Radon measures. This problem turned out to be difficult, and its solution has a long and rich history. Therefore, it is natural to call it the Riesz-Radon-Frechet problem of characterization of integrals. Important stages of its solution are associated with such eminent mathematicians as Banach (1937-1938), Saks (1937-1938), Kakutani (1941), Halmos (1950), Hewitt (1952), Edwards (1953), Prokhorov (1956), Bourbaki (1969), and others. Essential ideas and technical tools were developed by A.D. Alexandrov (1940-1943), Stone (1948-1949), Fremlin (1974), and others. Most of this paper is devoted to the contemporary stage of the solution of the problem, connected with papers of Koenig (1995-2008), Zakharov and Mikhalev (1997-2009), and others. The general solution of the problem is presented in the form of a parametric theorem on characterization of integrals which directly implies the characterization theorems of the indicated authors. Bibliography: 60 titles.

  12. Fresh and composted industrial sludge restore soil functions in surface soil of degraded agricultural land.

    Science.gov (United States)

    Arif, Muhammad Saleem; Riaz, Muhammad; Shahzad, Sher Muhammad; Yasmeen, Tahira; Ashraf, Muhammad; Siddique, Muhammad; Mubarik, Muhammad Salman; Bragazza, Luca; Buttler, Alexandre

    2018-04-01

    A field study was conducted to test the potential of 5-year consecutive application of fresh industrial sludge (FIS) and composted industrial sludge (CIS) to restore soil functions at surface (0-15cm) and subsurface (15-30cm) of the degraded agricultural land. Sludge amendments increased soil fertility parameters including total organic carbon (TOC), soil available nitrogen (SAN), soil available phosphorus (SAP) and soil available potassium (SAK) at 0-15cm depth. Soil enzyme activities i.e. dehydrogenase (DHA), β-glucosidase (BGA) and alkaline phosphatase (ALp) were significantly enhanced by FIS and CIS amendments in surface soil. However, urease activity (UA) and acid phosphatase (ACp) were significantly reduced compared to control soil. The results showed that sludge amendments significantly increased microbial biomass nitrogen (MBN) and microbial biomass phosphorus (MBP) at both soil depth, and soil microbial biomass carbon (MBC) only at 0-15cm depth. Significant changes were also observed in the population of soil culturable microflora (bacteria, fungi and actinomycetes) with CIS amendment in surface soil suggesting persistence of microbial activity owing to the addition of organic matter source. Sludge amendments significantly reduced soil heavy metal concentrations at 0-15cm depth, and the effect was more pronounced with CIS compared to unamended control soil. Sludge amendments generally had no significant impact on soil heavy metal concentrations in subsoil. Agronomic viability test involving maize was performed to evaluate phytotoxicity of soil solution extract at surface and sub-surface soil. Maize seeds grown in solution extract (0-15cm) from sludge treated soil showed a significant increase of relative seed germination (RSG), relative root growth (RRG) and germination index (GI). These results suggested that both sludge amendments significantly improved soil properties, however, the CIS amendment was relatively more effective in restoring soil functions

  13. Determinants for further wishes for cosmetic and reconstructive interventions in 1652 patients with surgical treated carcinomas of the oral cavity.

    Science.gov (United States)

    Holtmann, Henrik; Spalthoff, Simon; Gellrich, Nils-Claudius; Handschel, Jörg; Lommen, Julian; Kübler, Norbert R; Krüskemper, Gertrud; Rana, Majeed; Sander, Karoline

    2017-12-01

    The impairment of the appearance is a major problem for patients with carcinomas of the oral cavity. These patients want to recover their preoperative facial appearance. Some do not realize that this is not always possible and hence develop a desire for further cosmetic and reconstructive surgery (CRS) which often causes psychological problems. The desire of patients for CRS ( N  = 410; 26%) has been acquired in this DÖSAK rehab study including multiple reasons such as medical, functional, aesthetic and psychosocial aspects. They relate to the parameters of diagnosis, treatment and postoperative rehabilitation. Patients without the wish for CRS ( N  = 1155; 74%) served as control group. For the surgeons, knowledge of the patient's views is relevant in the wish for CRS. Nevertheless, it has hardly been investigated for patients postoperatively to complete resection of oral cancer. In this retrospective cross-sectional study, questionnaires with 147 variables were completed during control appointments. Thirty-eight departments of Oral and Maxillofacial Surgery took part, and 1652 German patients at least 6 months after complete cancer resection answered the questions. Additionally, a physician's questionnaire ( N  = 1489) was available. Statistical analysis was performed with SPSS vers. 22. The patient's assessment of their appearance and scarring are the most important criteria resulting in wishes for CRS. Furthermore, functional limitations such as eating/swallowing, pain of the facial muscles, numb regions in the operating field, dealing with the social environment, return to work, tumour size and location, removal and reconstruction are closely related. The wish for CRS depends on diverse functional psychosocial and psychological parameters. Hence, it has to be issued during conversation to improve rehabilitation. A decision on the medical treatment can be of greater satisfaction if the surgeon knows the patients' needs and is able to compare them with

  14. Nowotwory skóry u chorych po przeszczepieniu narządów

    Directory of Open Access Journals (Sweden)

    Beata Imko-Walczuk

    2011-04-01

    Full Text Available Nowotwory stają się jedną z głównych przyczyn zgonów chorych poudanym przeszczepieniu narządów. Stale rosnąca liczba chorych żyjącychz przeszczepionym narządem, a jednocześnie znacznie większazachorowalność, agresywny, szybki postęp choroby nowotworoweji niepomyślne rokowanie wymagają szczególnego podejścia onkologicznegow tej populacji. W pracy dokonano przeglądu nowotworówskóry występujących u chorych po przeszczepieniach narządów, któresą najczęstszymi zmianami nowotworowymi w tej grupie pacjentówi mają często odmienny obraz kliniczny niż w grupie chorych immunokompetentnych.W omawianej populacji nowotwory skóry – rak płaskonabłonkowy(SCC i rak podstawnokomórkowy (BCC występująnajczęściej. Również takie nowotwory, jak: mięsak Kaposiego, czerniak,chłoniaki, nowotwory okolic anogenitalnych, rak z komórek Merklaoraz inne rzadkie guzy mogą występować częściej u chorych otrzymującychleczenie immunosupresyjne. Istotne jest zapoznanie sięz cechami i odmiennościami klinicznymi dotyczącymi nowotworówu chorych po przeszczepieniach narządowych, aby móc je rozpoznaćw jak najwcześniejszym stadium rozwoju.

  15. Evaluation of oxidative response and tissular damage in rat lungs exposed to silica-coated gold nanoparticles under static magnetic fields

    Directory of Open Access Journals (Sweden)

    Ferchichi S

    2016-06-01

    Full Text Available Soumaya Ferchichi,1 Hamdi Trabelsi,1 Inès Azzouz,1 Amel Hanini,2 Ahmed Rejeb,3 Olfa Tebourbi,1 Mohsen Sakly,1 Hafedh Abdelmelek1 1Laboratory of Integrative Physiology, Faculty Of Sciences of Bizerte, 2Laboratory of Vascular Pathology, Carthage University, Carthage 3Laboratory of Pathological Anatomy, National School of Veterinary Medicine of Sidi Thabet, Manouba Univeristy, Manouba, Tunisia Abstract: The purpose of our study was the evaluation of toxicological effects of silica-coated gold nanoparticles (GNPs and static magnetic fields (SMFs; 128 mT exposure in rat lungs. Animals received a single injection of GNPs (1,100 µg/kg, 100 nm, intraperitoneally and were exposed to SMFs, over 14 days (1 h/day. Results showed that GNPs treatment induced a hyperplasia of bronchus-associated lymphoid tissue. Fluorescence microscopy images showed that red fluorescence signal was detected in rat lungs after 2 weeks from the single injection of GNPs. Oxidative response study showed that GNPs exposure increased malondialdehyde level and decreased CuZn-superoxide dismutase, catalase, and glutathione peroxidase activities in rat lungs. Furthermore, the histopathological study showed that combined effects of GNPs and SMFs led to more tissular damages in rat lungs in comparison with GNPs-treated rats. Interestingly, intensity of red fluorescence signal was enhanced after exposure to SMFs indicating a higher accumulation of GNPs in rat lungs under magnetic environment. Moreover, rats coexposed to GNPs and SMFs showed an increased malondialdehyde level, a fall of CuZn-superoxide dismutase, catalase, and glutathione peroxidase activities in comparison with GNPs-treated group. Hence, SMFs exposure increased the accumulation of GNPs in rat lungs and led to more toxic effects of these nanocomplexes. Keywords: malondialdehyde, catalase, superoxide dismutase, glutathione peroxidase, bronchus-associated lymphoid tissue, nanotoxicity, histopathological study

  16. Oral cancer malnutrition impacts weight and quality of life.

    Science.gov (United States)

    Gellrich, Nils-Claudius; Handschel, Jörg; Holtmann, Henrik; Krüskemper, Gertrud

    2015-03-27

    Diet is important for both quality of life (QoL) and survival of patients with oral cancer. Their intake of food is impeded by functional restrictions in chewing and swallowing. In the DÖSAK REHAB STUDY 1652 patients from 38 hospitals within the German-language area of Germany; Austria and Switzerland were examined with regard to functional and psychological variables having an impact on diet. Chewing and swallowing are correlated with mobility of the tongue and the mandible as well as opening of the mouth. Thirty five percent of the patients lost weight; 41% maintained their weight and 24% gained weight. The QoL of patients who were able to maintain their weight and of those who gained weight was significantly better than that of patients who lost weight. A normal diet was important for maintaining weight. Mashed food; liquid food and loss of appetite were closely associated with loss of weight; although it was possible for nutritional counseling and dietary support to be implemented particularly favorably in this respect. Due to problems with eating patients' strength deteriorated; thus restricting activity. Radiotherapy had a negative impact on diet and weight. It influenced sense of taste; dryness of the mouth; swelling and discomfort when ingesting food. Pain and scars in the region of the operation also cause patients to dislike hard; spicy and sour food. Support from a nutritional counselor in implementing a calorie-rich diet remedied this and such support needs to be integrated into patient management. The fact that a poor nutritional status is of such great importance is well-known; but what is often lacking is the systematic implementation of continued professional nutritional counseling over a long period of time; weight control and psycho-social support of the operated patients; particularly those who also have had radiotherapy.

  17. Oral Cancer Malnutrition Impacts Weight and Quality of Life

    Directory of Open Access Journals (Sweden)

    Nils-Claudius Gellrich

    2015-03-01

    Full Text Available Diet is important for both quality of life (QoL and survival of patients with oral cancer. Their intake of food is impeded by functional restrictions in chewing and swallowing. In the DÖSAK REHAB STUDY 1652 patients from 38 hospitals within the German-language area of Germany; Austria and Switzerland were examined with regard to functional and psychological variables having an impact on diet. Chewing and swallowing are correlated with mobility of the tongue and the mandible as well as opening of the mouth. Thirty five percent of the patients lost weight; 41% maintained their weight and 24% gained weight. The QoL of patients who were able to maintain their weight and of those who gained weight was significantly better than that of patients who lost weight. A normal diet was important for maintaining weight. Mashed food; liquid food and loss of appetite were closely associated with loss of weight; although it was possible for nutritional counseling and dietary support to be implemented particularly favorably in this respect. Due to problems with eating patients’ strength deteriorated; thus restricting activity. Radiotherapy had a negative impact on diet and weight. It influenced sense of taste; dryness of the mouth; swelling and discomfort when ingesting food. Pain and scars in the region of the operation also cause patients to dislike hard; spicy and sour food. Support from a nutritional counselor in implementing a calorie-rich diet remedied this and such support needs to be integrated into patient management. The fact that a poor nutritional status is of such great importance is well-known; but what is often lacking is the systematic implementation of continued professional nutritional counseling over a long period of time; weight control and psycho-social support of the operated patients; particularly those who also have had radiotherapy.

  18. From bench to application: current practices in tissue engineering and its realisation at maxillofacial units in Germany, Austria and Switzerland.

    Science.gov (United States)

    Smeets, Ralf; El-Moawen, Ahmed; Jung, Ole; Hanken, Henning; Hartjen, Philip; Heiland, Max; Kansy, Katinka; Kloss, Frank; Kolk, Andreas

    2014-10-01

    Over the last 20 years, the highly interdisciplinary field of tissue engineering (TE) has become an established subspecialty in research facilities all over the world. Numerous methods and protocols are available for various research intentions and aims, but there are no data indicating which of these methods and resources are generally used. This study is an overview of the resources and methods that are commonly applied in TE research in general, and in the field of oral and maxillofacial surgery (OMFS) in Germany, Austria and Switzerland. The DÖSAK collaborative group for TE developed a detailed questionnaire and collected information from participating university hospitals in these three countries. We evaluated the availability of research facilities, in vitro realisation and in vivo designs for animal studies in these departments. 11 units who replied, out of 35 we contacted, conducted research on bone regeneration in interdisciplinary research facilities. 10 departments used xenogeneic and alloplastic scaffolds for in vitro and in vivo applications. In this case, the most commonly utilised trademarks were Bio-Oss(®) and CERASORB(®). 9 units used osteoblasts (73%) and 10 proliferation assays in vitro, whereas rats served as the standard animal model for histology/immunohistochemistry in 6. All research units were interested in establishing a platform for research exchange and communication. This study shows that tissue engineering is well established and highly accepted in most participating university hospitals and research facilities. The presented data, together with data published in a foregoing paper will help arrange more readily available standardised procedures for further investigations. Copyright © 2014 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  19. Livestock-Associated Methicillin Resistant and Methicillin Susceptible Staphylococcus aureus Sequence Type (CC)1 in European Farmed Animals: High Genetic Relatedness of Isolates from Italian Cattle Herds and Humans

    Science.gov (United States)

    Alba, Patricia; Feltrin, Fabiola; Cordaro, Gessica; Porrero, María Concepción; Kraushaar, Britta; Argudín, María Angeles; Nykäsenoja, Suvi; Monaco, Monica; Stegger, Marc; Aarestrup, Frank M.; Butaye, Patrick; Franco, Alessia; Battisti, Antonio

    2015-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) Sequence Type (ST)1, Clonal Complex(CC)1, SCCmec V is one of the major Livestock-Associated (LA-) lineages in pig farming industry in Italy and is associated with pigs in other European countries. Recently, it has been increasingly detected in Italian dairy cattle herds. The aim of this study was to analyse the differences between ST1 MRSA and methicillin-susceptible S. aureus (MSSA) from cattle and pig herds in Italy and Europe and human isolates. Sixty-tree animal isolates from different holdings and 20 human isolates were characterized by pulsed-field gel electrophoresis (PFGE), spa-typing, SCCmec typing, and by micro-array analysis for several virulence, antimicrobial resistance, and strain/host-specific marker genes. Three major PFGE clusters were detected. The bovine isolates shared a high (≥90% to 100%) similarity with human isolates and carried the same SCCmec type IVa. They often showed genetic features typical of human adaptation or present in human-associated CC1: Immune evasion cluster (IEC) genes sak and scn, or sea; sat and aphA3-mediated aminoglycoside resistance. Contrary, typical markers of porcine origin in Italy and Spain, like erm(A) mediated macrolide-lincosamide-streptograminB, and of vga(A)-mediated pleuromutilin resistance were always absent in human and bovine isolates. Most of ST(CC)1 MRSA from dairy cattle were multidrug-resistant and contained virulence and immunomodulatory genes associated with full capability of colonizing humans. As such, these strains may represent a greater human hazard than the porcine strains. The zoonotic capacity of CC1 LA-MRSA from livestock must be taken seriously and measures should be implemented at farm-level to prevent spill-over. PMID:26322785

  20. Interaction between nanoparticles generated by zinc chloride treatment and oxidative responses in rat liver

    Directory of Open Access Journals (Sweden)

    Azzouz I

    2013-12-01

    Full Text Available Inès Azzouz, Hamdi Trabelsi, Amel Hanini, Soumaya Ferchichi, Olfa Tebourbi, Mohsen Sakly, Hafedh AbdelmelekLaboratory of Integrative Physiology, Faculty of Sciences of Bizerte, Carthage University, TunisiaAbstract: The aim of the present study was to investigate the interaction of zinc chloride (3 mg/kg, intraperitoneally [ip] in rat liver in terms of the biosynthesis of nanoparticles. Zinc treatment increased zinc content in rat liver. Analysis of fluorescence revealed the presence of red fluorescence in the liver following zinc treatment. Interestingly, the co-exposure to zinc (3 mg/kg, ip and selenium (0.20 mg/L, per os [by mouth] led to a higher intensity of red fluorescence compared to zinc-treated rats. In addition, X-ray diffraction measurements carried out on liver fractions of zinc-treated rats point to the biosynthesis of zinc sulfide and/or selenide nanocomplexes at nearly 51.60 nm in size. Moreover, co-exposure led to nanocomplexes of about 72.60 nm in size. The interaction of zinc with other mineral elements (S, Se generates several nanocomplexes, such as ZnS and/or ZnSe. The nanocomplex ZnX could interact directly with enzyme activity or indirectly by the disruption of mineral elements' bioavailability in cells. Subacute zinc or selenium treatment decreased malondialdehyde levels, indicating a drop in lipid peroxidation. In addition, antioxidant enzyme assays showed that treatment with zinc or co-treatment with zinc and selenium increased the activities of glutathione peroxidase, catalase, and superoxide dismutase. Consequently, zinc complexation with sulfur and/or selenium at nanoscale level could enhance antioxidative responses, which is correlated to the ratio of number of ZnX nanoparticles (X=sulfur or X=selenium to malondialdehyde level in rat liver.Keywords: nanocomplexes biosynthesis, antioxidative responses, X-ray diffraction, fluorescence microscopy, liver

  1. Effects of Alternative Fuels and Aromatics on Gas-Turbine Particle Emissions

    Science.gov (United States)

    Thornhill, K. L., II; Moore, R.; Winstead, E.; Anderson, B. E.; Klettlinger, J. L.; Ross, R. C.; Surgenor, A.

    2015-12-01

    This presentation describes experiments conducted with a Honeywell GTCP36-150 Auxiliary Power Unit (APU) to evaluate the effects of varying fuel composition on particle emissions. The APU uses a single-stage compressor stage, gas turbine engine with a can-type combustor to generate bypass flow and electrical power for supporting small aircraft and helicopters. It is installed in a "hush-house" at NASA Glenn Research Center and is configured as a stand-alone unit that can be fueled from an onboard tank or external supply. It operates at constant RPM, but its fuel flow can be varied by changing the electrical load or volume of bypass flow. For these tests, an external bank of resistors were attached to the APU's DC and AC electrical outlets and emissions measurements were made at low, medium and maximum electrical current loads. Exhaust samples were drawn from several points downstream in the exhaust duct and fed to an extensive suite of gas and aerosol sensors installed within a mobile laboratory parked nearby. Aromatic- and sulfur-free synthetic kerosenes from Rentech, Gevo, UOP, Amyris and Sasol were tested and their potential to reduce PM emissions evaluated against a single Jet A1 base fuel. The role of aromatic compounds in regulating soot emissions was also evaluated by adding metered amounts of aromatic blends (Aro-100, AF-Blend, SAK) and pure compounds (tetracontane and 1-methylnaphthalene) to a base alternative fuel (Sasol). Results show that, relative to Jet A1, alternative fuels reduce nonvolatile particle number emissions by 50-80% and--by virtue of producing much smaller particles—mass emissions by 65-90%; fuels with the highest hydrogen content produced the greatest reductions. Nonvolatile particle emissions varied in proportion to fuel aromatic content, with additives containing the most complex ring structures producing the greatest emission enhancements.

  2. Factors associated with medication information in diabetes care: differences in perceptions between patients and health care professionals

    Directory of Open Access Journals (Sweden)

    Längst G

    2015-10-01

    Full Text Available Gerda Längst,1 Hanna Marita Seidling,2,3 Marion Stützle,2,3 Dominik Ose,1 Ines Baudendistel,1 Joachim Szecsenyi,1 Michel Wensing,1,4 Cornelia Mahler1 1Department of General Practice and Health Services Research, University Hospital of Heidelberg, Heidelberg, Germany; 2Cooperation Unit Clinical Pharmacy, University of Heidelberg, Heidelberg, Germany; 3Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Heidelberg, Germany; 4Radboud University Nijmegen Medical Centre, Scientific Institute for Quality of Healthcare, Nijmegen, the Netherlands Purpose: This qualitative study in patients with type 2 diabetes and health care professionals (HCPs aimed to investigate which factors they perceive to enhance or impede medication information provision in primary care. Similarities and differences in perspectives were explored.Methods: Eight semistructured focus groups were conducted, four with type 2 diabetes patients (n=25 and four with both general practitioners (n=13 and health care assistants (n=10. Sessions were audio and video recorded, transcribed verbatim, and subjected to computer-aided qualitative content analysis.Results: Diabetes patients and HCPs broadly highlighted similar factors as enablers for satisfactory medication information delivery. Perceptions substantially differed regarding impeding factors. Both patients and HCPs perceived it to be essential to deliver tailored information, to have a trustful and continuous patient–provider relationship, to regularly reconcile medications, and to provide tools for medication management. However, substantial differences in perceptions related to impeding factors included the causes of inadequate information, the detail required for risk-related information, and barriers to medication reconciliation. Medication self-management was a prevalent topic among patients, whereas HCPs’ focus was on fulfilling therapy and medication management responsibilities

  3. Effects of Biochar and Lime on Soil Physicochemical Properties and Tobacco Seedling Growth in Red Soil

    Directory of Open Access Journals (Sweden)

    ZHU Pan

    2015-12-01

    Full Text Available Red soil, mainly found in the southern China, is developed in a warm, moist climate. The main property of the soils is strong acidity, aluminum toxicity, and low available nutrients. In this study, different effects of biochar and lime on soil physicochemical properties and tobacco growth were determined in red soil, so as to provide a scientific foundation for soil improvement tobacco field. A pot experiment was designed and conducted at four biochar levels(0, 0.5%, 1%, 2% and normal lime level (0.3% to study effects of two different soil amendments on red soil pH, exchangeable aluminum(Exc-Al and exchangeable manganese(Exc-Mn, available nutrients and organic carbon (SOC. Meanwhile, agronomic traits, biomass and leaves elements of tobacco were also tested. Results showed that the agronomic characters and biomass of tobacco seedling had changed effectively after biochar or lime was added. Under 0.5%, 1% biochar treatment, the content of nitrogen(N, phosphorus(P, potassium(K, calcium(Ca and magnesium(Mg in tobacco leaves substantially raised. However, when 2% biochar was applied, leaves N content declined by 9.3%. Compared with the control, leaves N, P and Ca content increased observably in the lime treatment. However, its K and Mg content decreased by 9.0% and 13.3% respectively. Alkaline nitrogen(SAN, available phosphorus (SAP, available potassium (SAK, and exchangeable calcium (Exc-Ca and exchangeable magnesium (Exc-Mg were improved obviously in soil applied with biochar. Only the content of Exc-Ca was significantly increased in lime treatment. In addition, it was beneficial to improve soil pH and reduce soil Exc-Al when biochar or lime had been used. Thus, both biochar and lime are propitious to increase soil pH value, lessen soil Exc-Al content, and improve the growth of tobacco seedling. Furthermore, biochar application also can raise the content of available nutrient and SOC in red soil.

  4. Antifungal activity of redox-active benzaldehydes that target cellular antioxidation

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    Mahoney Noreen

    2011-05-01

    Full Text Available Abstract Background Disruption of cellular antioxidation systems should be an effective method for control of fungal pathogens. Such disruption can be achieved with redox-active compounds. Natural phenolic compounds can serve as potent redox cyclers that inhibit microbial growth through destabilization of cellular redox homeostasis and/or antioxidation systems. The aim of this study was to identify benzaldehydes that disrupt the fungal antioxidation system. These compounds could then function as chemosensitizing agents in concert with conventional drugs or fungicides to improve antifungal efficacy. Methods Benzaldehydes were tested as natural antifungal agents against strains of Aspergillus fumigatus, A. flavus, A. terreus and Penicillium expansum, fungi that are causative agents of human invasive aspergillosis and/or are mycotoxigenic. The yeast Saccharomyces cerevisiae was also used as a model system for identifying gene targets of benzaldehydes. The efficacy of screened compounds as effective chemosensitizers or as antifungal agents in formulations was tested with methods outlined by the Clinical Laboratory Standards Institute (CLSI. Results Several benzaldehydes are identified having potent antifungal activity. Structure-activity analysis reveals that antifungal activity increases by the presence of an ortho-hydroxyl group in the aromatic ring. Use of deletion mutants in the oxidative stress-response pathway of S. cerevisiae (sod1Δ, sod2Δ, glr1Δ and two mitogen-activated protein kinase (MAPK mutants of A. fumigatus (sakAΔ, mpkCΔ, indicates antifungal activity of the benzaldehydes is through disruption of cellular antioxidation. Certain benzaldehydes, in combination with phenylpyrroles, overcome tolerance of A. fumigatus MAPK mutants to this agent and/or increase sensitivity of fungal pathogens to mitochondrial respiration inhibitory agents. Synergistic chemosensitization greatly lowers minimum inhibitory (MIC or fungicidal (MFC

  5. Evsel Atıklardan Elde Edilen Kompostun Mısır ve Biberin Gelişimi ve Besin Elementi İçeriğine Etkisi

    Directory of Open Access Journals (Sweden)

    Derviş AYNACI

    2016-04-01

    Full Text Available Araştırmada, 1 ay süre ile 10 ayrı haneden mutfak atıkları toplanmış, toplanan evsel atıklardan elde edilen kompostun sera koşullarında mısır ve biber bitkilerinin gelişimi ve besin elementi içeriğine etkisi araştırılmıştır. Deneme 2 kg toprak alan saksılarda yürütülmüş olup, kompostun 6 (0, 0.25, 0.50, 1.00, 2.00 ve 4.00 ton/da dozu uygulanmıştır. Araştırma, 4 paralelli olarak, tesadüf parselleri deneme desenine göre planlanmış ve 2 ay süreyle yürütülmüştür. Araştırma sonunda hasat edilen bitkilerde kuru ağırlık değerleriyle N, P, K, Ca, Mg, Fe, Cu, Zn ve Mn konsantrasyonları belirlenmiştir. Uygulanan kompost miktarı arttıkça bitki kuru ağırlığı artmış, biber bitkisinin N konsantrasyonunda 2-2.4 kat arasında artışlar görülmüştür. Mısır bitkisi N konsantrasyonları da kompost dozlarından olumlu etkilenmiş fakat burada dozlar arası fark önemli olmamıştır. Bitkilerde P, K ve Ca konsantrasyonları kompost miktarı arttıkça olumlu yönde etkilenmiş, biberde Fe, Zn ve Mn konsantrasyonları, mısırda ise Mn konsantrasyonu etkisi istatistiksel anlamda önemli bulunmuştur.

  6. Healthcare- and Community-Associated Methicillin-Resistant Staphylococcus aureus (MRSA and Fatal Pneumonia with Pediatric Deaths in Krasnoyarsk, Siberian Russia: Unique MRSA's Multiple Virulence Factors, Genome, and Stepwise Evolution.

    Directory of Open Access Journals (Sweden)

    Olga E Khokhlova

    Full Text Available Methicillin-resistant Staphylococcus aureus (MRSA is a common multidrug-resistant (MDR pathogen. We herein discussed MRSA and its infections in Krasnoyarsk, Siberian Russia between 2007 and 2011. The incidence of MRSA in 3,662 subjects was 22.0% and 2.9% for healthcare- and community-associated MRSA (HA- and CA-MRSA, respectively. The 15-day mortality rates for MRSA hospital- and community-acquired pneumonia (HAP and CAP were 6.5% and 50%, respectively. MRSA CAP cases included pediatric deaths; of the MRSA pneumonia episodes available, ≥27.3% were associated with bacteremia. Most cases of HA-MRSA examined exhibited ST239/spa3(t037/SCCmecIII.1.1.2 (designated as ST239Kras, while all CA-MRSA cases examined were ST8/spa1(t008/SCCmecIV.3.1.1(IVc (designated as ST8Kras. ST239Kras and ST8Kras strongly expressed cytolytic peptide (phenol-soluble modulin α, PSMα; and δ-hemolysin, Hld genes, similar to CA-MRSA. ST239Kras pneumonia may have been attributed to a unique set of multiple virulence factors (MVFs: toxic shock syndrome toxin-1 (TSST-1, elevated PSMα/Hld expression, α-hemolysin, the staphylococcal enterotoxin SEK/SEQ, the immune evasion factor SCIN/SAK, and collagen adhesin. Regarding ST8Kras, SEA was included in MVFs, some of which were common to ST239Kras. The ST239Kras (strain OC3 genome contained: a completely unique phage, φSa7-like (W, with no att repetition; S. aureus pathogenicity island SaPI2R, the first TSST-1 gene-positive (tst+ SaPI in the ST239 lineage; and a super copy of IS256 (≥22 copies/genome. ST239Kras carried the Brazilian SCCmecIII.1.1.2 and United Kingdom-type tst. ST239Kras and ST8Kras were MDR, with the same levofloxacin resistance mutations; small, but transmissible chloramphenicol resistance plasmids spread widely enough to not be ignored. These results suggest that novel MDR and MVF+ HA- and CA-MRSA (ST239Kras and ST8Kras emerged in Siberian Russia (Krasnoyarsk associated with fatal pneumonia, and also with ST

  7. Phase Behavior, Solid Organic Precipitation, and Mobility Characterization Studies in Support of Enhanced Heavy Oil Recovery on the Alaska North Slope

    Energy Technology Data Exchange (ETDEWEB)

    Shirish Patil; Abhijit Dandekar; Santanu Khataniar

    2008-12-31

    amount of geographically diverse data, it is not possible to develop a comprehensive predictive model. Based on the comprehensive phase behavior analysis of Alaska North Slope crude oil, a reservoir simulation study was carried out to evaluate the performance of a gas injection enhanced oil recovery technique for the West Sak reservoir. It was found that a definite increase in viscous oil production can be obtained by selecting the proper injectant gas and by optimizing reservoir operating parameters. A comparative analysis is provided, which helps in the decision-making process.

  8. A Livestock-Associated, Multidrug-Resistant, Methicillin-Resistant Staphylococcus aureus Clonal Complex 97 Lineage Spreading in Dairy Cattle and Pigs in Italy.

    Science.gov (United States)

    Feltrin, Fabiola; Alba, Patricia; Kraushaar, Britta; Ianzano, Angela; Argudín, María Angeles; Di Matteo, Paola; Porrero, María Concepción; Aarestrup, Frank M; Butaye, Patrick; Franco, Alessia; Battisti, Antonio

    2016-02-01

    Pandemic methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 97 (CC97) lineages originated from livestock-to-human host jumps. In recent years, CC97 has become one of the major MRSA lineages detected in Italian farmed animals. The aim of this study was to characterize and analyze differences in MRSA and methicillin-susceptible S. aureus (MSSA) mainly of swine and bovine origins. Forty-seven CC97 isolates, 35 MRSA isolates, and 6 MSSA isolates from different Italian pig and cattle holdings; 5 pig MRSA isolates from Germany; and 1 human MSSA isolate from Spain were characterized by macrorestriction pulsed-field gel electrophoresis (PFGE) analysis, multilocus sequence typing (MLST), spa typing, staphylococcal cassette chromosome mec (SCCmec) typing, and antimicrobial resistance pattern analysis. Virulence and resistance genes were investigated by PCR and microarray analysis. Most of the isolates were of SCCmec type V (SCCmec V), except for two German MRSA isolates (SCCmec III). Five main clusters were identified by PFGE, with the German isolates (clusters I and II) showing 60.5% similarity with the Italian isolates, most of which (68.1%) grouped into cluster V. All CC97 isolates were Panton-Valentine leukocidin (PVL) negative, and a few (n = 7) tested positive for sak or scn. All MRSA isolates were multidrug resistant (MDR), and the main features were erm(B)- or erm(C)-mediated (n = 18) macrolide-lincosamide-streptogramin B resistance, vga(A)-mediated (n = 37) pleuromutilin resistance, fluoroquinolone resistance (n = 33), tet(K) in 32/37 tet(M)-positive isolates, and blaZ in almost all MRSA isolates. Few host-associated differences were detected among CC97 MRSA isolates: their extensive MDR nature in both pigs and dairy cattle may be a consequence of a spillback from pigs of a MRSA lineage that originated in cattle as MSSA and needs further investigation. Measures should be implemented at the farm level to prevent spillover to humans in intensive farming

  9. Healthcare- and Community-Associated Methicillin-Resistant Staphylococcus aureus (MRSA) and Fatal Pneumonia with Pediatric Deaths in Krasnoyarsk, Siberian Russia: Unique MRSA's Multiple Virulence Factors, Genome, and Stepwise Evolution

    Science.gov (United States)

    Khokhlova, Olga E.; Hung, Wei-Chun; Wan, Tsai-Wen; Iwao, Yasuhisa; Takano, Tomomi; Higuchi, Wataru; Yachenko, Svetlana V.; Teplyakova, Olga V.; Kamshilova, Vera V.; Kotlovsky, Yuri V.; Nishiyama, Akihito; Reva, Ivan V.; Sidorenko, Sergey V.; Peryanova, Olga V.; Reva, Galina V.; Teng, Lee-Jene; Salmina, Alla B.; Yamamoto, Tatsuo

    2015-01-01

    Methicillin-resistant Staphylococcus aureus (MRSA) is a common multidrug-resistant (MDR) pathogen. We herein discussed MRSA and its infections in Krasnoyarsk, Siberian Russia between 2007 and 2011. The incidence of MRSA in 3,662 subjects was 22.0% and 2.9% for healthcare- and community-associated MRSA (HA- and CA-MRSA), respectively. The 15-day mortality rates for MRSA hospital- and community-acquired pneumonia (HAP and CAP) were 6.5% and 50%, respectively. MRSA CAP cases included pediatric deaths; of the MRSA pneumonia episodes available, ≥27.3% were associated with bacteremia. Most cases of HA-MRSA examined exhibited ST239/spa3(t037)/SCCmecIII.1.1.2 (designated as ST239Kras), while all CA-MRSA cases examined were ST8/spa1(t008)/SCCmecIV.3.1.1(IVc) (designated as ST8Kras). ST239Kras and ST8Kras strongly expressed cytolytic peptide (phenol-soluble modulin α, PSMα; and δ-hemolysin, Hld) genes, similar to CA-MRSA. ST239Kras pneumonia may have been attributed to a unique set of multiple virulence factors (MVFs): toxic shock syndrome toxin-1 (TSST-1), elevated PSMα/Hld expression, α-hemolysin, the staphylococcal enterotoxin SEK/SEQ, the immune evasion factor SCIN/SAK, and collagen adhesin. Regarding ST8Kras, SEA was included in MVFs, some of which were common to ST239Kras. The ST239Kras (strain OC3) genome contained: a completely unique phage, φSa7-like (W), with no att repetition; S. aureus pathogenicity island SaPI2R, the first TSST-1 gene-positive (tst+) SaPI in the ST239 lineage; and a super copy of IS256 (≥22 copies/genome). ST239Kras carried the Brazilian SCCmecIII.1.1.2 and United Kingdom-type tst. ST239Kras and ST8Kras were MDR, with the same levofloxacin resistance mutations; small, but transmissible chloramphenicol resistance plasmids spread widely enough to not be ignored. These results suggest that novel MDR and MVF+ HA- and CA-MRSA (ST239Kras and ST8Kras) emerged in Siberian Russia (Krasnoyarsk) associated with fatal pneumonia, and also with ST

  10. Transformation of Resources to Reserves: Next Generation Heavy-Oil Recovery Techniques

    Energy Technology Data Exchange (ETDEWEB)

    Stanford University; Department of Energy Resources Engineering Green Earth Sciences

    2007-09-30

    (BN) of the crude oil. A significant number of laboratory-scale tests were made to evaluate the solution gas drive potential of West Sak (AK) viscous oil. The West Sak sample has a low acid number, low asphaltene content, and does not appear foamy under laboratory conditions. Tests show primary recovery of about 22% of the original oil in place under a variety of conditions. The acid number of other Alaskan North Slope samples tests is greater, indicating a greater potential for recovery by heavy-oil solution gas drive. Effective cold production leads to reservoir pressure depletion that eases the implementation of thermal recovery processes. When viewed from a reservoir perspective, thermal recovery is the enhanced recovery method of choice for viscous and heavy oils because of the significant viscosity reduction that accompanies the heating of oil. One significant issue accompanying thermal recovery in cold environments is wellbore heat losses. Initial work on thermal recovery found that a technology base for delivering steam, other hot fluids, and electrical heat through cold subsurface environments, such as permafrost, was in place. No commercially available technologies are available, however. Nevertheless, the enabling technology of superinsulated wells appears to be realized. Thermal subtasks focused on a suite of enhanced recovery options tailored to various reservoir conditions. Generally, electrothermal, conventional steam-based, and thermal gravity drainage enhanced oil recovery techniques appear to be applicable to 'prime' Ugnu reservoir conditions to the extent that reservoir architecture and fluid conditions are modeled faithfully here. The extent of reservoir layering, vertical communication, and subsurface steam distribution are important factors affecting recovery. Distribution of steam throughout reservoir volume is a significant issue facing thermal recovery. Various activities addressed aspects of steam emplacement. Notably, hydraulic

  11. PREFACE: 2nd Workshop on Germanium Detectors and Technologies

    Science.gov (United States)

    Abt, I.; Majorovits, B.; Keller, C.; Mei, D.; Wang, G.; Wei, W.

    2015-05-01

    The 2nd workshop on Germanium (Ge) detectors and technology was held at the University of South Dakota on September 14-17th 2014, with more than 113 participants from 8 countries, 22 institutions, 15 national laboratories, and 8 companies. The participants represented the following big projects: (1) GERDA and Majorana for the search of neutrinoless double-beta decay (0νββ) (2) SuperCDMS, EDELWEISS, CDEX, and CoGeNT for search of dark matter; (3) TEXONO for sub-keV neutrino physics; (4) AGATA and GRETINA for gamma tracking; (5) AARM and others for low background radiation counting; (5) as well as PNNL and LBNL for applications of Ge detectors in homeland security. All participants have expressed a strong desire on having better understanding of Ge detector performance and advancing Ge technology for large-scale applications. The purpose of this workshop was to leverage the unique aspects of the underground laboratories in the world and the germanium (Ge) crystal growing infrastructure at the University of South Dakota (USD) by brining researchers from several institutions taking part in the Experimental Program to Stimulate Competitive Research (EPSCoR) together with key leaders from international laboratories and prestigious universities, working on the forefront of the intensity to advance underground physics focusing on the searches for dark matter, neutrinoless double-beta decay (0νββ), and neutrino properties. The goal of the workshop was to develop opportunities for EPSCoR institutions to play key roles in the planned world-class research experiments. The workshop was to integrate individual talents and existing research capabilities, from multiple disciplines and multiple institutions, to develop research collaborations, which includes EPSCor institutions from South Dakota, North Dakota, Alabama, Iowa, and South Carolina to support multi-ton scale experiments for future. The topic areas covered in the workshop were: 1) science related to Ge

  12. THE MODERN WAY OF THREATS, CURSE AND IMPRECATION: SONGS AND FOLKSONGS KÜFÜR ETMENİN, LANET VE BEDDUA OKUMANIN ÇAĞDAŞ YOLU: ŞARKI VE TÜRKÜLER

    Directory of Open Access Journals (Sweden)

    Mustafa ŞENEL

    2009-12-01

    Full Text Available The elements of folk literature are hidden in details of music which is the most important source and carrier of richness in various regions of the country.The contribution of this attitude wording to the teaching of mother language in the works of artists comes true involuntarily. Simple melody, known prayer in our songs and folksongs undertake a task of teaching curses.This kind of teaching method is processed unconsciously in today’s popular songs. In this study, we example how the unspeakable consepts become a part of our lives via music by analysing folk songs and popular songs. Yurdun çeşitli yörelerinde var olan zenginliğin en önemli taşıyıcıları ve kaynağı olan müziğin inceliklerinde halk edebiyatının unsurları gizlidir. Bu tavrın ve üslubun sanatçıların oluşturdukları eserlerdeki anadilin öğretilmesine olan katkısı, başlangıçta istem dışı bir öğrenim şeklinde gerçekleşmektedir. Şarkı ve türkülerimizdeki akılda kalan kolay melodi, halka tanıdık gelen dua, beddua lanet okuma ve hatta küfür şekillerinin öğretilmesinde de önemli bir görev üstlenmiştir. Bu tarz bir öğrenme yöntemi, günümüz popüler şarkılarında da farkında olmadan işlenilmektedir. Zira müzik aracılığıyla geleneksel değerlerimizin, hiçbir sakınca görülmeden artık böyle bir öğrenme yöntemi ile öğretebilme yöntemini tercih edilebileceği sonucuna varılabilir. Çalışmamızda hem geleneksel türkülerimizden hem de son dönemlerin güncel şarkı ve türkülerinden yola çıkarak normal şartlarda insanların birbirlerine söyleyemedikleri bu kavramların (beddua , lanet okuma ve küfür müzikle beraber günlük hayatımıza girişi incelenmiştir.

  13. Volcanic history and petrography of the Pliocene Etrüsk Stratovolcano, E Turkey

    Science.gov (United States)

    Oyan, Vural; Keskin, Mehmet; Lebedev, Vladimir; Sharkov, Evgenii; Lustrino, Michele; Mattioli, Michele

    2010-05-01

    rhyolite. All these units and also caldera walls are cut by a set of radial dykes. Both trachydacitic/rhyolitic lavas and radial dykes are made up of plagioclase, biotite and quartz phenocrysts. Some textures in the intermediate and felsic lavas (e.g., glass inclusions and sieve texture in plagioclase phenocrysts etc.) suggest that magma mixing might have been an important process in the magma chamber beneath Mt. Etrusk although such textures can also be related to the variations of volatile content of the magma. The Quaternary eruptions on the W flank of the Etrusk volcano are represented by plagioclase-olivine-clinopyroxene-phyric basalts. Our geochemical database indicates that the edifice-forming trachitic lavas are alkaline in character whereas overlying thracyandesites and post caldera thrachydacites/rhyolites plot on the subalkaline-alkaline divide on TAS diagram, displaying transitional characteristics. Quaternary fissure eruptions in the SW of the volcano classify as subalkaline basalts. All these lavas display enrichment in LIL and LREE elements relative to HFS and HREE respectively. These characteristics may be a reflection of the composition of mantle source region, although the effects of magma chamber processes (e.g. AFC and mixing) on magma composition cannot be ruled out. REFERENCE Şengör, A.M.C., Özeren, M.S., Keskin, M., Sakınç, M., Özbakır, A.D. and Kayan, I. (2008). Eastern Turkish high plateau as a small Turkic-type orogen: implications for post-collisional crust-forming processes in Turkic-type orogens, Earth Science Reviews, 90(1-2), 1-48.

  14. Globalization, differentiation and drinking cultures, an anthropological perspective

    Directory of Open Access Journals (Sweden)

    Thomas Wilson

    2004-12-01

    Full Text Available L’alcool et sa consommation ne renvoient pas simplement au domaine économique. L’alcool est devenu aujourd’hui une partie intégrale des relations sociales dans différentes cultures au point où son importance globale est souvent sous-estimée par ses plus ardents critiques. En dépit de ses conséquences directes sur la santé, sa consommation a pris une certaine ampleur dans le monde industriel développé. Certainement son rôle central dans la construction des identités individuelles explique sa position clé au sein des sociétés. Que nous dit le saké à propos du Japon ou le vin de Bourgogne sur la France? Que nous dit la consommation ou l’abstinence d’alcool sur les questions d’identité individuelle, d’ethnicité, de classe et de culture? Quelle place tient l’alcool dans la définition de soi et dans la notion de résistance? Répondre à ces questions et à d’autres est le but essentiel de cet article qui examine la consommation d’alcool à travers différentes cultures et ce que boire signifie pour ceux qui choisissent de consommer ou de s’abstenir. De l’Irlande à Hong-Kong, Mexico à l’Allemagne, l’alcool occupe un certain nombre de fonctions sociales, religieuses, politiques et familiales. Les cultures du boire définissent ces consommations dans le cadre plus large des pratiques sociales et montrent comment classes sociales, ethnicité et nationalisme peuvent s’exprimer à travers cette commodité. En partant d’approches de terrain, les contributeurs analysent l’interface entre culture et pouvoir dans les bars et pubs, la signification des images publicitaires, le rôle de ces boissons dans la vie quotidienne. Le résultat est la première publication comparative sur les questions de l’impact que la consommation d’alcool a sur l’identité nationale dans le monde aujourd’hui.Alcohol is not only big business, it has become an essential part of social relations in so many cultures that

  15. TÜRKİYEDEKİ ULAŞTIRMA SİSTEMLERİNİN ANALİZİ VE ULAŞTIRMA POLİTİKALARI

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    Ali Payıdar AKGÜNGÖR

    2004-03-01

    Full Text Available Sosyo-ekonomik ve sosyo-kültürel yapılaşmanın doğal bir sonucu olarak ortaya çıkan ulaştırma talebi değerlendirilirken, ulaştırma sistemlerinin bir bütün olarak ele alınarak incelenmesi gereklidir. Gerek yolcu, gerekse yük taşımacılığı için seçilecek olan ulaştırma sisteminin hızlı, ekonomik, güvenli, çevreye az zarar veren ve ülke koşullarına uygun bir ulaştırma sisteminin olması arzu edilir. Ancak bir sistemin, sıralanan bu hususların hepsini birden bünyesinde toplaması oldukça zordur. Her sistemin birbirlerine göre üstünlükleri ve sakıncaları vardır. Bu nedenledir ki, büyük yatırımlar ülke genelinde tesis edilirken ileriye yönelik çok kapsamlı planlamalar yapılmalıdır. Ayrıca ülke kaynaklarının ulaştırma sistemleri arasında akılcı bir şekilde nasıl dağıtılması gerektiği araştırılmalı ve ulaştırma sistemleri arasında koordineli çalışmayı sağlayacak bir ulaşım planı hazırlanmalıdır. Bu planın başarısı ise hiç kuşkusuz sistemlerden birine ağırlık vermek yerine kombine taşımacılık ile mümkün olacaktır. Ülkemizin üç yanı denizlerle çevrili iken deniz yolu ile yapılan taşımacılığın % 1 seviyesinin çok altında olması ve karayolu ile yapılan yük ve yolcu taşımacılığının ise % 95 seviyelerine çıkması Türkiye'deki ulaştırma politikalarının sorgulanması gerektiğini ortaya çıkarmaktadır. Bu bildiride Türkiye'deki ulaştırma sistemlerinin ve ulaşım politikalarının tarihsel süreç içerisinde genel bir değerlendirmesi yapılarak sorunlar ortaya konulmakta ve çözüm önerileri sunulmaktadır.

  16. Blood on their hands: How heroines in biblical and Apocryphal literature differ from those in ancient literature regarding violence

    Directory of Open Access Journals (Sweden)

    Robin Gallaher Branch

    2014-12-01

    van Herodotus, Homeros en Tacitus onthul interessante ooreenkomste. Hierdie artikel bespreek karakterstudies uit die verhaal van die Amasone – vrouekrygers wat nie geskroom het om hulle eie liggame te skend ter wille van die beter hantering van hulle wapens nie; die verhaal van Tomyris, wat ’n geveg teen Cyrus wen en sy kop in ’n sak, gevul met menslike bloed, geplaas het; Anchita, ’n Spartaanse moeder wat haar goedkeuring gee om haar seun lewend in tempel van Minerva af te seël; en Boadicea, wat ’n rebellie teen Rome aangevoer het waarin 80 000 Britte omgekom het. Die slotsom van hierdie artikelis dat Debora en Jael, Ester, en Judit, in teenstelling met vroue uit ander kulture, hulle inkrisistye tot geweldpleging gewend het slegs wanneer hulle volksgenote bedreig is. Hulle eenmalige dade is net tot die aggressors beperk en word waarskynlik deur ’n gevoel van erbarming getemper.

  17. DISCOVER Problem Matrisinin Revize Edilmesi ve Psikometrik Özelliklerinin İncelenmesi (An Investigation on the Revision of the DISCOVER Problem Matrix and its Psychometric Properties

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    Şule Güçyeter

    2011-12-01

    provided additional evidences related to its reliability and validity. Results of the study showed that the DPM has sufficient convergent and divergent validity because the more distant two problem types are from each other, the low-er the correlation between them (discriminant validity, and the closer the problem types are to each other, the larger the correlations between them (convergent validity. These findings are parallel to those obtained by Sak and Maker (2005. The new problem type added to the Matrix also had a good fit with the structure of Matrix. Furthermore, evidence also was obtained in terms of the Matrix’s discriminant validity. That is, 7th graders scored higher than the 6th graders on the Matrix-based instrument. This study provided research evidence about the reliability and validity of the revised DISCOVER Matrix. Because, it’s a problem continuum model, more problem types should be added to the Model.

  18. “Cihanda Türk” Ve “Şarkımız” Şiirlerinin Varlıkbilim Açısından / Ontolojik Açıdan Karşılaştırılması Ontological Comparison Of “Cihanda Türk” And “Şarkimiz” Poems

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    Salim DURUKOĞLU

    2013-09-01

    Full Text Available According to Gustave Lanson, since three-quarters of personalityof even the most authentic authors is composed of borrowed elementsas the synthesis of past generations and literary movements; thehorizons of every poet or writer involve other literary texts writtenpreviously by other poets or writers. In a mythological context, the onlyperson who knows whether something has been uttered before is Hz.Adem or his spouse Hz. Havva. Civilization is defined as the greatestsynthesis of thought humanity has attained. It is not possible that anauthor would not confront with other authors, discover and appropriatethem just like it is not possible for cultures which do not confront otherricher cultures and civilizations and benefit them to develop andadvance to the level of civilization. Within these network of relations, wecan arrive to the deduction and definition that authorship (poesy withinthe scope of our text is the greatest synthesis of thought an authorattains.The interaction between writers is both normal and interestingenough to consider, and an important field of study in comparativeliterature. In this paper, the poem Cihanda Türk (Turk in the world byBekir Sıtkı Erdoğan and Şarkımız (Our song by Necip Fazıl Kısakürekwere compared from an ontological perspective. In the paper shorthistory of comparative literature was given and meaning strata inliterary work was summarized according to ontological method and thenfor the comparison, first the publishing processes of the poems werehandled; thus authentic texts were reached; next assessments weredone by analyzing the literary strata interwoven in the literary work asentity strata such as sound strata, meaning strata, and differentschematic views strata. As a result, the boundaries of similaritiesbetween two poems were detected without aiming at grading ordegrading them; general conclusions were made about which of theconcepts such as allusion, imitation, quotation, indirect citation

  19. Survival of the lichen model system Circinaria gyrosa before flight to the ISS (EXPOSE R2 mission)

    Science.gov (United States)

    De la Torre Noetzel, Rosa

    potential to space and Mars conditions, contributing to our understanding of extremotolerance and the Lithopanspermia hypothesis [7]. References [1] Rabbow, E., und Rettberg, Petra und Barczyk, Simon und Bohmeier, Maria und Parpart, André und Panitz, Corinna und Horneck, Gerda und von Heise-Rotenburg, Ralf und Hoppenbrouwers, Tom und Willnecker, Rainer und Baglioni, Pietro und Demets, René und Dettmann, Jan und Reitz, Guenther (2012) EXPOSE-E: An ESA Astrobiology Mission 1.5 Years in Space. Astrobiology, 12 (5), Seiten 374-386. Mary Ann Liebert, Inc.. DOI: 10.1089/ast.2011.0760. [2] De la Torre, R. L.G. Sancho, G. Horneck, A.de los Ríos, J. Wierzchos, K. Olsson-Francis, C.S. Cockell, Rettberg P., T. Berger, J.P. de Vera, S. Ott, J. Martinez Frías, P.Gonzalez Melendi M.M. Lucas, M. Reina, A. Pintado, R.Demets. Survival of lichens and bacteria exposed to outer space conditions. Results of the Lithopanspermia experiments. Icarus, doi:10.1016/j.icarus.2010.03.010 (2010). [3] Sanchez, F.J., E. Mateo-Martí, J. Raggio, J. Meessen, J. Martinez-Frias, L. Gª Sancho, S. Ott and R. de la Torre. The resistance of the lichen Circinaria gyrosa (nom. provis.) towards simulated Mars conditions - a model test for the survival capacity of an eukaryotic extremophyle. Planetary and Space Science 72, 102-110 (2012). [4] de Vera JP and the BIOMEX-Team (2012) Supporting Mars exploration: BIOMEX in Low Earth Orbit and further astrobiological studies on the Moon using Raman and PanCam technology. Planetary and Space Science, 74 (1), Seiten 103-110. Elsevier. DOI:10.1016/j.pss.2012.06.010. [5] Meeßen J, Sánchez FJ, Brandt A, Balzer EM, de la Torre R, Sancho LG, de Vera JP, Ott S (2013) Extremotolerance and resistance of lichens: Comparative studies on five species used in astrobiological research I. Morphological and anatomical characteristics. Origins of Life and Evolution of Biospheres 43 (3): 283-303 [6] Meeßen J, Sánchez FJ, Sadowsky A, de Vera JP, de la Torre R, Ott S (2013

  20. FRESHWATER FISH FARMING CONDITIONS IN 1999 AND THE PRODUCTION PLAN FOR 2000

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    Zlatko Homen

    2000-09-01

    at 7.945,43 tons of the freshwater fish, of which 7.173,33 tons are warm-water fish species, and 772,10 tons are cold-water species. Carp farming is the most dominante and most significant production branch in both of the years mentioned. Distribution of the produced freshwater fish was conducted as follows. The largest quantity of the produced fish was placed on the market through wholesale (48,51 percent. This was fallowed by the distribution of produced fish for reproduction purposes (plantation which comprises 40,25 percent. Retail trade claimed 4,39 percent and personal use recorded (recreatinal fishing 2,04 percent. Production losses due to diseases or other factors made up 4,81 percent of the overall production. The overall areas of the fish farms in 1999 were 11.921.06 hectares. The actual production sites made up 9.782 hectares. Compared to 1998, the overall areas decreased for 5,84 percentt, while the production sites were increased by 0,94 percent. When taking into account the production areas and the arhieved production for 1999, the fish production average for carp farming ponds was 632,63 kilograms per hectare. Of course, as we already highlighted this is the average, and according to the data provided, some fish farms arhieved cost-effective production, i. e. a produstion of over 1.000 kilograms per hectare. In trout farming ponds, the fish production average amounded to 133,17 tons per hectare. During 1999. 13.501,93 tons of fish food were used. Of this quantity, 12.553,13 tons were used in carp ponds and 948,81 tons in trout ponds. Naturally, corn is still most predominant food for carp species fish. As to the use of various raw materials, the overall amound used was 2.690,21 tons. Among the fixed assets for 1999, there were 218 boats, 74 outboard engines, 121 landing nets, 57 scatter guns. Among the accessories there were mats (known in colloquial Croatian terms as sak and meredov, receptacle for fish transport (tubs, pumps, devices for fish sorting

  1. Bilim ve Sanat Merkezi Öğret‐menlerinin Üstün ve Özel Yetenekli Öğrenciler için Tasarlanan Doğa ve Bilim Kampı Hakkında Görüşleri (Perceptions of Science and Art Centers’ Teachers about a Nature and Science Camp Designed for Gifted and Talented Students

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    Necati Hırça

    2012-06-01

    all of them worked in the SACs. As they were aware of the situation, they stated that they needed this kind of programs and various science activities from other education faculties to improve their skills in order to teach gifted students in science.Identification, training and employment of gifted individuals significantly contribute to the development of society. Training of these individuals in every academic level will provide value-added benefits to the future of our country (BSMİDR, 2010. The lack of these condi-tions will impede or delay their self-esteem, self-perception, discipline and achievement (Sak, 2011.

  2. Effektive representasjoner? Forventninger til og bekymringer for forskning på befruktede egg

    Directory of Open Access Journals (Sweden)

    Marie Auensen Antonsen

    2011-05-01

    Full Text Available I Norge har vi hatt kontroverser omkring regulering avhumanmedisinsk bioteknologi siden 1980-tallet. Denneartikkelen analyserer et lite utsnitt av disse reguleringsdebattene,nærmere bestemt kontroversen omkring forskningpå befruktede egg. Med utgangspunkt i skriftlig materialeknyttet til tre reguleringsrunder (1994, 2003/2004 og2008 undersøker vi her hvordan ulike aktører arbeidet forå ramme inn denne kontroversen, bl.a. ved hjelp av ulikevitenskapelige og politiske representasjoner av det befruktedeegget.Vi finner at det i perioden 1987–2007 ble arbeidet medulike innramminger som utgangspunkt for retoriske ogpolitiske strategier: På den ene siden ser vi forsøk på å innrammekontroversen i et risikorammeverk som først ogfremst fokuserte på de potensielle negative sidene vedhumanmedisinsk bioteknologi, og som spesielt vektlarespekten for det ufødte liv. På den andre siden ser vi atman arbeidet med en forventningsinnramming som lahovedvekten på håpet om nye behandlingsregimer foralvorlig syke mennesker.Forbudet mot forskning på befruktede egg som ble vedtatti 1987, ble opprettholdt i 1994 og 2003. Med lovendringeni 2008 fikk vi imidlertid et markant brudd i dennorske lovgivningspraksisen, da forskning på befruktedeegg ble tillatt på visse premisser. Vi argumenterer for at den viktigste årsaken til denne lovendringen var Mehmet-saken, en sak som medførtesåkalte «oversvømmelser» (Callon 1998 i begge innrammingsforsøkenesom er omtalt ovenfor. Mehmet-saken eksponerte samtidig et generelt demokratiskdilemma. Saken illustrerte hvor sårbare lovregler og etiske prinsippkan være for det som for allmennheten fremstår som helt urimelig, og dennesaken etterspør slik sett mer hybride måter å tenke forholdet mellom det universelleog det partikulære, mellom prinsipiell etikk og lekmannsskjønn, mellomfakta og verdier som utgangspunkt for politikkutforming.Nøkkelord: humanmedisinsk bioteknologi, forskning på befruktede egg

  3. IMPORTANT CHANGE IN RELIGIO-LEGAL STANDARDIZATION OF OTTOMAN PRODUCTS: PASSAGE TO CERTIFICATE OF THE SEAL “IT IS CLEAN/TÂHİRDİR” OSMANLI’DA ÜRÜNLERİN DİNÎ/ŞER‘Î STANDARDİZASYONUNDA DÖNÜM NOKTASI: TÂHİRDİR DAMGALI SERTİFİKASYONA GEÇİŞ

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    Mehmet YILDIZ

    2010-01-01

    Full Text Available It is known that the Ottoman state implemented austere certification of products monitored by organizations such as ihtisab office/ office of the superintendent of guilds and markets and akhi office/ urban fraternity ruling over parts of Anatolia in late Seljuk and early Ottoman times. The monitoring process that was implemented based on religio-legal perspective or material quality aspect moved to an important phase with a critical decision made in modern times: The seal of “it is clean/tâhirdir” was introduced to include inedible products for the first time to be supervised by religio-legal standarts. This decision was made to protect Muslims from products that might contained harmful ingredients according to religio-legal norms. This move was made before the kosher certification that was formed within the Jewish community in America, which became a certain measure of food standart later in the world. This decision also can provide historical background for the practice of halal food certificates in the world. The notion of “it is clean” becomes more evident in the midst of today’s world where genetically modified organisms became so widespread to the level that threatens the health of human generation now. This article aims to study the relevant Ottoman official documents on this issue probably for the first time, and share them with the academic world. Osmanlı devleti ve toplumunda ürünlerin, standartları hisbe/ihtisap ve ahîlik teşkilatları gibi kurumlar vasıtasıyla denetlenen oldukça ciddi sertifikasyon uygulamasına tabi tutuldukları bilinmektedir. Gerek dinî/şer‛î boyutuyla gerekse maddi/nesnel kalite yönleriyle yürütülen bu denetleme işlemi, modern zamanlarda gerçekten çok çarpıcı bir kavşak noktasına ulaştırılmıştır: Özellikle dinî/şer‛î ölçütlerin gıda ürünleri dışındaki ürünlerde de gözetilerek Müslümanların kullanmalarında sakınca bulunmayan ürünlere t

  4. Šaukėnų šnektos veiksmažodžio asmenavimo sistema (vientisinės formos

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    Albertas Rosinas

    2011-12-01

    -stem verbs constitute a highly productive and stable class while in the subdialect there have remained only four i̯a (former i - stem verbs: tí·l̑ : ti·líeti, gál̑ : galíeti, mí·l̑ : mi·líeti  and gúl̑ : gulíeti. The verbs of the 2nd conjugation (or a-stem are also rather productive.The Šaukėnai subdialect has preserved some remnants of athematic conjugation. Some verbs are impersonal, e.g. per̃št, the others possess all personal forms derived from underlying form stems, e.g. mĩ·i̯ktu, etc.The categories in the Šaukėnai subdialect indicate a variety of symbolization.The categories of person and number are usually represented by grammatical morphemes, or endings (i.e. the morphological markers of the categories: /-u/, /-a·u/symbolize the categories of person and number, i.e.  the 1st person and the singular, /-i/, /-a· /, /-e· / -- the 2nd person and the singular /-am/, /-uom/, /-iem/, /-ma/--  the 1st person and the plural, /-at/, /-uot/, /-iet/, /-te/-- the 2nd person and the plural. The ending forms of the 3rd person represent the category of person, i.e. the 3rd person only.The article rejects the opinion, which dominates in Lithuanian linguistic literature, as if the verbal form endings could also represent the category of tense. It is complete misunderstanding, cf. sak-á·u (present and suk-á·u (past, mùš-ù (present and mùš-ù (future, etc. As evidenced by the data from the Šaukėnai subdialect, the tense can be expressed by syntactic category markers, phonological means, cf. mat-á·u and mač̑-ǽ·u, various formants (infixes, such as –n-, -st-, -s-, cf. añk and ãka, ki̲m̃b and kì̲ba, ti̲r̃pst  and ti̲r̃pa, dí̲́rbu and dí̲́rpsu, suffixes, cf. dí̲́rb-a·u and dí̲́rb-dav-a·u as well as vowel gradation, cf. ker̃t and ki̲r̃ta, etc. However, only the simple form endings of the indicative and subjunctive moods can express the mood.The forms of the subjunctive mood, alongside their specific

  5. Turkish Journal of Chemistry’nin Bibliyometrik Analizi / Bibliometric Analysis of Turkish Journal of Chemistry

    Directory of Open Access Journals (Sweden)

    Hatice Gülşen Birinci

    2008-10-01

    multiple authorships in TJC? What are the institutional affiliations of authors? Does the distribution of authors fit Bradford’s, Lotka’s and Price’s Law and 80/20 Rule? Which types of sources get cited more often in articles? Which journals are the most cited? According to cited journals what are the core journals in chemistry? With regard to impact factor, what is the place of TJC in JCR and SCI?The most productive authors are Sakıp Ali and İhsan Çalış. Distribution of authors does not fit Bradford’s, Lotka’s and Price’s Law and 80/20 Rule, but distirbution of citations fit Bradford and 80/20 Rule. Contributors affiliated with Hacettepe University, Ankara University, and Ataturk University. Journals received %82 of all citations in the TJC. Turkish Journal of Chemistry, Journal of the American Chemical Society, Phytochemistry and Journal of Organic Chemistry were the most frequently cited journals. Number of references made to TJC has been growing consistently since 1996.

  6. ASİDİK YAGIŞLARIN TRİTİCUM VULGARE ( BUGDAY ve ZEA • • • • • MA YS SACCHARA TA (MISIR BITKILERINE ETKILERI

    Directory of Open Access Journals (Sweden)

    NEVİN YALÇIN

    1999-12-01

    Full Text Available Bu çalışmada, asidik yağışların Triticum Vulgare (Buğday ve Zea Mays Saccbarata ( Mısır bitkile rine et ki leri incel enmiştir. Bu a1naçla, 24 adet 20x20x30 cn1 boyutundaki teneke saksı lara ekilen tohumlar pH 1 � 2, 3, 4. 5, 6 olan HN03 ve H2S04 ç özel til e ri ile bir ay bo yunc a sulanmışlar dır.T. Vulgar e ve Z.M. Saccharata yap r a k lar ı n d a k loroz i s (sa r arma ve flecking (benekleşme görülmüştür.Büyüme, 15. g ünde n sonra durınuştur. pH s ı düşük olan çö zel t i l er ile sulanan bitkilerde boyca enge llennıe görülmüş, çürüme daha önce b aş ! an1ış tı r . Ayrıca as i di k çöz elti lerl e sulamanın tohum çim l e n m es i ni gec i ktirdi ğ i gözlenıniştir. Biyomas değ e r lerinde de k ayıpla r kaydedilıniştir. Düşük pH derecelerinde ka yıp l arı n daha fazla olduğu b eli r le nnı i ş t ir. Her iki bit k inin kök ve gövdelerinin anatemisinde bir bozulına görülmeıniştir. ABSTRACT In this study, the effects of acid rains on Triticum Vu l g a re (\\Vheat and Zea Mays Saccharata (Com were investigated. For this purpose, seeds were sowed to 24 tin pots at diı n ensions of 20x20x30 cm and they were vvatered with HN03 and H2S04 solutions which to be pH L 2, 3, 4, 5, 6 for o ne month. T.Vulgare and Z.M. Saccharata leavcs showed chlorosis and flecking. The growing stopped after 15 days. At solutions with low pH, p I ant l e ngt h s w ere n1easured shorter and rotting w as begun earlier than otlıers. It also inhibited seed gennination by de lay ing the same. The bi o mass values alsa s h owe d a loss and this was the h i g hest at the low pH degree s . The root and stern defo rmat i ons in each the two s p c ci es were not seemed . I. GİRİŞ Atmosferin kirl errmesi sonucu rneydana gelen asit yağmurlar1 veya asit ç ö k e J n 1 es i sanayinin, termik santr allerin , ulaşun araçlan n ın ve fosil yakıtların yaydığı SOx , kükürt oksit ve NOx , azot oksit

  7. Chemical Methods for Ugnu Viscous Oils

    Energy Technology Data Exchange (ETDEWEB)

    Kishore Mohanty

    2012-03-31

    The North Slope of Alaska has large (about 20 billion barrels) deposits of viscous oil in Ugnu, West Sak and Shraeder Bluff reservoirs. These shallow reservoirs overlie existing productive reservoirs such as Kuparuk and Milne Point. The viscosity of the Ugnu reservoir on top of Milne Point varies from 200 cp to 10,000 cp and the depth is about 3300 ft. The same reservoir extends to the west on the top of the Kuparuk River Unit and onto the Beaufort Sea. The depth of the reservoir decreases and the viscosity increases towards the west. Currently, the operators are testing cold heavy oil production with sand (CHOPS) in Ugnu, but oil recovery is expected to be low (< 10%). Improved oil recovery techniques must be developed for these reservoirs. The proximity to the permafrost is an issue for thermal methods; thus nonthermal methods must be considered. The objective of this project is to develop chemical methods for the Ugnu reservoir on the top of Milne Point. An alkaline-surfactant-polymer (ASP) formulation was developed for a viscous oil (330 cp) where as an alkaline-surfactant formulation was developed for a heavy oil (10,000 cp). These formulations were tested in one-dimensional and quarter five-spot Ugnu sand packs. Micromodel studies were conducted to determine the mechanisms of high viscosity ratio displacements. Laboratory displacements were modeled and transport parameters (such as relative permeability) were determined that can be used in reservoir simulations. Ugnu oil is suitable for chemical flooding because it is biodegraded and contains some organic acids. The acids react with injected alkali to produce soap. This soap helps in lowering interfacial tension between water and oil which in turn helps in the formation of macro and micro emulsions. A lower amount of synthetic surfactant is needed because of the presence of organic acids in the oil. Tertiary ASP flooding is very effective for the 330 cp viscous oil in 1D sand pack. This chemical formulation

  8. Okuma Yazma Öğretimi Yöntemleri Ve “Ses Temelli Cümle Yöntemi” Uygulaması The Methods Of Teaching Reading And Writing In Turkish: Practice The Phonetic Based Method

    Directory of Open Access Journals (Sweden)

    Raşit KOÇ

    2012-12-01

    ğrenmede ve bu işi zevkli bir alışkanlığa dönüştürmede okuma ve yazma öğretiminde nasıl bir yol izleneceği de önem kazanmaktadır.Ülkemizde dünyadaki gelişmelere paralel olarak okuma yazma öğretiminde kullanılan yöntemler de zaman içerisinde değişmiştir. Okuma yazma öğretiminde uzun süre harf yöntemi kullanılmıştır. Harf yöntemini sırasıyla ses yöntemi, hece yöntemi kelime ve cümle yöntemi izlemiştir.Davranışçı kuram merkeze alınarak hazırlanmış olan eski Türkçe programı öğrencileri ezbere sevk ettiği, etkili ve kalıcı bir okuma alışkanlığı kazandırmada yeterli olmadığı için eleştirilere muhatap olmuştur. Zaman zaman revizyon geçiren eski program 2005 yılında yerini yeni programa bırakmıştır.Temel felsefesini yapılandırmacı yaklaşımın oluşturduğu yeni Türkçe programında okuma yazma öğretim yöntemi olarak ses temelli cümle yöntemi benimsenmiştir. Bu yöntemle beraber dik temel harflerle yapılan yazı öğretimi yerine bitişik eğik yazı kullanılmaya başlanmıştır.Bu çalışmada, okuma yazma öğretiminde günümüze kadar kullanılan yöntemler ve bu yöntemlerin faydalı ve sakıncalı yönleri belirtildikten sonra yeni hazırlanan Türkçe programında yer alan ses temelli cümle yöntemiyle ilgili düşüncelere yer verilecektir.

  9. Dergilerden Özetler

    Directory of Open Access Journals (Sweden)

    Mete Korkut Gülmen

    1997-10-01

    Full Text Available ANİ BEBEK ÖLÜMÜNE PATOLOJİ AÇISINDAN YAKLAŞIM - ANLAŞMA VEYA KARARSIZLIK? The Pathological Approach to Sudden Infant Death - Consensus or Confusion? RW Byard, LE Becker, PJ Berry, PE Campbell, K Fitzge- rald, JMN Hiltorı, HF Krous, TO Rogrıum AmJ Forensic Med Pathol 1996;17(2:103-5. Ani bebek ölümü sendromu (ABÖS ile ilgili temel sorun, otopsiyi yapan hekim tarafından diğer ani bebek ölüm nedenlerini araştırma ve dışlama işlemlerine gösterilen özenin derecesine bağlı bir eleyici tanı olmasıdır. Ama dikkatli bif otopsi yapıldıktan sonra bile, sadece patolojik zemine dayanarak kasıtlı ya da kaza sonucu oluşan asfiksiyi ani bebek sendromundan ayırmak mümkün olmayabilir. Ayrıca, ülkelerin kendi içinde veya ülkeler arasında protokoller farklıdır. Yatağında ölü bulunan ve ABÖS olarak tanımlanan her bebeğe otopsi yapılmamaktadır. Bu çerçevede ABÖS tanısı konamadığı ve ölüm nedeninin saptanmadan kaldığı vurgulanmalıdır. Olası etyolojik mekanizmaların (ki bunlar kompleks, birden fazladır ve birbirleri ile ilgili değildir anlaşılma eksikliği nedeni ile ilgili diğer güçlükler de ortaya çıkmaktadır. Makroskopik inceleme ve cesedin disseksiyonundan sonra histolojik muayene, araştırma ve saklama için dokuların alıkonulması da dava ile ilgili bir sorun olabilir. İkinci ABÖS global strateji toplantısında (Stavan- gerda yapılmıştır aşağıdaki asgari standardlar savunulmuştur. Toplum ve ailenin yararına, tüm beklenmeyen bebek ölümleri tam olarak incelenmelidir. Ölüm nedeni ve şeklinin saptanması için aşağıdakilerin yapılması gereklidir. 1.\tOlay yeri ve çevresinin değerlendirilmesi eğitimli ve işin uzmanı kişiler tarafından yürütülmelidir. 2.\tBebeğin veya çocuğun ve ailenin öyküsünü de içeren anamnez gözden geçirilmelidir. 3.\tAyrıntılı otopsi ve uygun yardımcı çalışmalar yapılmalıdır. 4.\tOlgu baştan başa gözden ge

  10. 6th International Symposium on Molecular Allergology (ISMA

    Directory of Open Access Journals (Sweden)

    Christiane Hilger

    2016-10-01

    -allergic humans Almedina Kurtaj, Christoph Hillebrand, Gerda Fichtinger, Martin Danzer, Christian Gabriel, Theresa Thalhamer, Sandra Scheiblhofer, Josef Thalhamer, Richard Weiss P4 Analyzing the cross-reactivity profile of the major ragweed allergen Amb a 1 Martin Wolf, Michael Hauser, Ulrike Pichler, Teresa Twaroch, Gabriele Gadermaier, Christof Ebner, Hidenori Yokoi, Toshiro Takai, Alain Didierlaurent, Adriano Mari, Peter Briza, Heidrun Behrendt, Angela Neubauer, Frank Stolz, Fátima Ferreira, Michael Wallner P5 LTP (Pru p 3 sensitisation in skin prick test: which means in clinical practice? Sara Carvalho, Tatiana Lourenço, Joana Cosme, Fátima Cabral Duarte, Amélia Spínola Santos, Ana Célia Costa, Manuel Pereira Barbosa P6 IgE profiles, allergen exposure and lifestyle of 501 Austrian pupils: investigation of influences on the development of allergic sensitizations Teresa Stemeseder, Eva Klinglmayr, Bettina Schweidler, Lisa Lueftenegger, Stephanie Moser, Patrick Doppler, Roland Lang, Martin Himly, Gertie J. Oostingh, Arne Bathke, Joerg Zumbach, Thomas Hawranek, Gabriele Gadermaier P7 Molecular profiles of sensitization to perennial inhalant allergens in a middle European region Petr Panzner, Martina Vachova, Tomas Vlas, Marek Maly P8 Evolution of the IgE response to house dust mite allergen molecules in childhood Daniela Posa, Serena Perna, Stephanie Hofmaier, Laura Hatzler, Alexander Rohrbach, Carl-Peter Bauer, Ute Hoffmann, Johannes Forster, Fred Zepp, Antje Schuster, Philippe Stock, Ulrich Wahn, Linus Grabenhenrich, Thomas Keil, Susanne Lau, Kuan-Wei Chen, Yvonne Resch, Susanne Vrtala, Rudolf Valenta, Paolo Maria Matricardi P9 Tropomyosin (Pen a1: to include or not to include in skin prick testing? Joana Cosme, Sara Carvalho, Tatiana Lourenço, Amélia Spínola Santos, Manuel Pereira Barbosa Immunoallergy Department - Hospital de Santa Maria – Centro Hospitalar Lisboa Norte, Lisbon, Portugal, Lisbon, Portugal; Immunoallergy Department - Hospital de Santa Maria

  11. Dergilerden Özetler

    Directory of Open Access Journals (Sweden)

    Mete Korkut Gülmen

    1997-10-01

    Full Text Available ANİ BEBEK ÖLÜMÜNE PATOLOJİ AÇISINDAN YAKLAŞIM - ANLAŞMA VEYA KARARSIZLIK? The Pathological Approach to Sudden Infant Death - Consensus or Confusion? RW Byard, LE Becker, PJ Berry, PE Campbell, K Fitzge- rald, JMN Hiltorı, HF Krous, TO Rogrıum AmJ Forensic Med Pathol 1996;17(2:103-5. Ani bebek ölümü sendromu (ABÖS ile ilgili temel sorun, otopsiyi yapan hekim tarafından diğer ani bebek ölüm nedenlerini araştırma ve dışlama işlemlerine gösterilen özenin derecesine bağlı bir eleyici tanı olmasıdır. Ama dikkatli bif otopsi yapıldıktan sonra bile, sadece patolojik zemine dayanarak kasıtlı ya da kaza sonucu oluşan asfiksiyi ani bebek sendromundan ayırmak mümkün olmayabilir. Ayrıca, ülkelerin kendi içinde veya ülkeler arasında protokoller farklıdır. Yatağında ölü bulunan ve ABÖS olarak tanımlanan her bebeğe otopsi yapılmamaktadır. Bu çerçevede ABÖS tanısı konamadığı ve ölüm nedeninin saptanmadan kaldığı vurgulanmalıdır. Olası etyolojik mekanizmaların (ki bunlar kompleks, birden fazladır ve birbirleri ile ilgili değildir anlaşılma eksikliği nedeni ile ilgili diğer güçlükler de ortaya çıkmaktadır. Makroskopik inceleme ve cesedin disseksiyonundan sonra histolojik muayene, araştırma ve saklama için dokuların alıkonulması da dava ile ilgili bir sorun olabilir. İkinci ABÖS global strateji toplantısında (Stavan- gerda yapılmıştır aşağıdaki asgari standardlar savunulmuştur. Toplum ve ailenin yararına, tüm beklenmeyen bebek ölümleri tam olarak incelenmelidir. Ölüm nedeni ve şeklinin saptanması için aşağıdakilerin yapılması gereklidir. 1.\tOlay yeri ve çevresinin değerlendirilmesi eğitimli ve işin uzmanı kişiler tarafından yürütülmelidir. 2.\tBebeğin veya çocuğun ve ailenin öyküsünü de içeren anamnez gözden geçirilmelidir. 3.\tAyrıntılı otopsi ve uygun yardımcı çalışmalar yapılmalıdır. 4.\tOlgu baştan başa gözden ge

  12. Kongre İzlenimleri

    Directory of Open Access Journals (Sweden)

    Yasemin Balcı

    2007-12-01

    çilere açtığı şarap mahzenleri var. Görülmeye değerdi. Kongrenin son günü, Portoya özel bir festival vardı. S. Joe festival olarak anılıyor. Bu festivalin özelliği bir nevi şaka ya da hoşgörü günü gibi olması idi. Bu festival nedeniyle Portekiz’in diğer şehirlerinden pek çok kişi şehre geldi. Her ne kadar herkes sabaha kadar sokaklarda olup eğlense de otellerde yer kalmıyor. Her tarafta rengârenk plastik çekiçler satılıyor. Çoluk çocuk, genç ihtiyar herkes bu çekiçlerden satın alıyor. Sokaklarda yanında bulunan ya da yanından geçen herkese bu çekiçle vuruyor. Kongre organizasyon komitesi de bu nedenle bizi çekiçsiz bırakmadı. Katılımcılara çekiç verdiler. Ayrıca, sokaklarda kötü koku ile özdeşleştirilen fesleğen saksıları (bizde güzel koku olarak bilinir ile çiçeklenmiş/tohuma dönmüş erkek soğanlar satılıyor. İnsanlar yapraklarını koparıp elini yanındaki-nin burnuna sürüyor. Soğanın tohumlu kısmını yüzüne kulağına vs. sürtüyor. Tüm bunlar bir nevi şaka, kimse kimseye kırılmıyor. Şehrin tüm meydanlarında konser platformları kuruluyor, herkes sokaklarda dans ediyor, Super Bock adlı bira çeşmelerinden biralar alınıp içiliyor. Ezilme tehlikesi geçirecek kadar insan seli olmasına karşın, en küçük bir taşkınlıkla karşılaşılmaması oldukça ilgimizi çekti. Gece yarısından sonra nehri baştan yaratacak şekilde yapılan havai fişek gösterisi ile havaya fırlatılan yüzlerce ateş balonları görmeye değerdi. Türkiye’den kongre katılımcıları Uzm. Dr. Özlem Ersoy Adli Tıp Kurumu Prof. Dr. Mete Gülmen Çukurova Üniversitesi Dr. Hüsniye Canan, Phd. Çukurova Üniversitesi Dr. Demet Meral Çukurova Üniversitesi Dr. Dilek Battal, Phd. Çukurova Üniversitesi Prof. Dr. Yasemin Balcı Eskişehir Osmangazi Üniversitesi Yard. Doç. Dr. Birol Demirel Gazi Üniversitesi Doç. Dr. Coşkun Yorulmaz İstanbul Üniversitesi Yard. Doç. Dr. Gökhan Ersoy