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... Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Samoa, San Marino, Sao Tome and Principe, Saudi Arabia, Self-Pay, Senegal, Serbia, Seychelles, Sierra Leone, Singapore, Sint Maarten (Dutch part), Slovakia (Slovak Republic), Slovenia, Solomon Islands, Somalia, South Africa, South Sudan, Spain ...

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End Date: 4 novembre 2009. Sujet: YOUTH UNEMPLOYMENT, YOUTH UNREST, TRAINING PROGRAMMES, INFORMATION TECHNOLOGY, YOUNG WORKERS. Région: North and Central America, South America, West Indies, Dominica, Grenada, Jamaica, Saint Kitts and Nevis, Saint Lucia, Trinidad and Tobago.

ClinicalTrials.gov

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... Peru Philippines Poland Portugal Puerto Rico Qatar Romania Russian Federation Rwanda Réunion Saint Kitts and Nevis Saudi ... you may be able to participate in or learn about new treatments that are being considered. Learn ...

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Région: North and Central America, South America, West Indies, Dominica, Grenada, Jamaica, Saint Kitts and Nevis, Saint Lucia, Trinidad and Tobago. Programme: Économies en réseaux. Financement total : CA$ 299,791.00. Partenariat pour l'accès à l'emploi grâce à la technologie dans les Amériques : initiative des ...

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Région(s): Guyana, West Indies, Saint Kitts and Nevis, Saint Lucia, Trinidad and Tobago. Financement total : CA$ 5,000,000.00. Agroforesterie et alimentation des moutons au Mali. Projet. L'élevage du mouton joue un rôle de premier plan pour ce qui est d'assurer la subsistance des ménages vivant en milieu rural au Mali ...

CIFSRF Call 6 Eligible Country List January 5.2015

International Development Research Centre (IDRC) Digital Library (Canada)

wmanchur

Saint Lucia. Sao Tome and Principe. Senegal. Seychelles. Sierra Leoneℓ. Somaliaℓ. South Africa. South Sudanℓ. Sri Lanka. St. Kitts and Nevis. Sudan. Swaziland. Tanzania. Togo. Trinidad and Tobago. Tunisia. Uganda†. Vietnam. Zambia. Zimbabwe. *Countries for which projects will have to address a research problem of ...

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Région: Guyana, West Indies, Saint Kitts and Nevis, Saint Lucia, Trinidad and Tobago. Financement total : CA$ 5,000,000.00. De la ferme à la fourchette : amélioration de la nutrition dans les Caraïbes. Projet. Le taux d'obésité est à la hausse dans les Caraïbes, surtout en raison du peu d'attention accordée à la production ...

Student-Teachers' Supervision as a Professional Development Activity: Building Work-Related Skills

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Minott, Mark A.; Willett, Ionie Liburd

2011-01-01

The purpose of this research was to identify and outline the work-related skills that cooperating teachers in the Cayman Islands and Saint Kitts-Nevis developed or reinforced as they supervised student-teachers. A qualitative case-study methodology was used. The findings indicate that cooperating teachers developed and reinforced essential…

De la ferme à la fourchette : liens entre productivité, nutrition et santé ...

International Development Research Centre (IDRC) Digital Library (Canada)

20 sept. 2013 ... Ce projet met à l'essai une démarche qui va « de la ferme à la fourchette » et qui établit des liens entre l'agriculture, d'une part, et la santé et la nutrition, d'autre part, pour s'attaquer aux problèmes que pose la sécurité alimentaire au Guyana, à Trinité-et-Tobago, à Saint-Kitts-et-Nevis. et à Sainte-Lucie.

La santé dans les Caraïbes Contrer l'obésité par la diversité des ...

International Development Research Centre (IDRC) Digital Library (Canada)

à Saint-Kitts-et-Nevis en raison de la détérioration qui se produit sur les exploitations agricoles, de l'exposition à la lumière solaire, des températures élevées et de la manipulation inappropriée dans les commerces de détail ? • des techniques simples comme l'utilisation de pellicule de plastique peuvent tripler la durée de.

Saine diversification des repas servis dans les écoles grâce aux ...

International Development Research Centre (IDRC) Digital Library (Canada)

Les pays des Caraïbes n'ont guère prêté attention à la production alimentaire locale, comptant plutôt sur des aliments transformés importés à forte teneur en calories qui ont contribué à des taux d'obésité élevés. À Trinité-et-Tobago et à Saint-Kitts-et-Nevis par exemple, les repas servis à l'école contiennent moins de 10 %.

Notes from the field: chikungunya virus spreads in the Americas - Caribbean and South America, 2013-2014.

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Fischer, Marc; Staples, J Erin

2014-06-06

In December 2013, the World Health Organization reported the first local transmission of chikungunya virus in the Western Hemisphere, with autochthonous cases identified in Saint Martin. Since then, local transmission has been identified in 17 countries or territories in the Caribbean or South America (Anguilla, Antigua and Barbuda, British Virgin Islands, Dominica, Dominican Republic, French Guiana, Guadeloupe, Guyana, Haiti, Martinique, Puerto Rico, Saint Barthelemy, Saint Kitts and Nevis, Saint Lucia, Saint Martin, Saint Vincent and the Grenadines, and Sint Maarten). As of May 30, 2014, a total of 103,018 suspected and 4,406 laboratory-confirmed chikungunya cases had been reported from these areas. The number of reported cases nearly doubled during the previous 2 weeks. More than 95% of the cases have been reported from five jurisdictions: Dominican Republic (38,656 cases), Martinique (30,715), Guadeloupe (24,428), Haiti (6,318), and Saint Martin (4,113). The highest incidences have been reported from Saint Martin (115 cases per 1,000 population), Martinique (76 per 1,000), Saint Barthelemy (74 per 1,000), and Guadeloupe (52 per 1,000). Further expansion of these outbreaks and spread to other countries in the region is likely.

Oral Hygiene and Handwashing Practices among Middle School Students in 15 Latin American and Caribbean Countries.

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McKittrick, T R; Jacobsen, K H

2015-06-01

To examine the relationship between infrequent toothbrushing and infrequent handwashing among middle school students from 15 Latin American and Caribbean countries (Antigua and Barbuda, Argentina, British Virgin Islands, Cayman Islands, Costa Rica, Grenada, Guatemala, Guyana, Peru, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and Grenadines, Suriname, Trinidad and Tobago, and Uruguay). A secondary analysis was done of nationally-representative data from 33 174 middle school students who participated in the Global School-based Student Health Survey (GSHS) between 2006 and 2011. In all 15 countries, the association between rarely brushing or cleaning teeth and rarely handwashing after using the toilet was significant for both boys and girls. The pooled odds ratio for this association was 6.7 (5.8, 7.7). Healthcare providers who notice signs of poor dental hygiene or infrequent bathing in adolescents should consider providing comprehensive hygiene education to their patients, since infrequent oral and body hygiene behaviours tend to co-exist and both are threats to health.

Nasopharyngeal Pneumococcal Colonization among Children after Pneumococcal Conjugate Vaccine Introduction

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Manoochehr Karami

2017-08-01

Full Text Available World Health Organization has recommended all countries to introduction of Pneumococcal Conjugate Vaccine (PCV in routine immunization schedule, especially those countries with higher rate of mortality in children. However, Islamic Republic of Iran and more than 50 other countries including Algeria, Antigua and Barbuda, Belarus, Belize, Bhutan, Bosnia and Herzegovina, Brunei Darussalam, Cabo Verde, Chad, China, Comoros, Cook Islands, Croatia, Cuba, Czech Republic, Democratic People's Republic of Korea, Dominica, Egypt, Equatorial Guinea, Estonia, Gabon, Grenada, Guinea, Haiti, India, Jamaica, Jordan, Malaysia, Maldives, Malta, Montenegro, Nauru, Poland, Romania, Saint Kitts and Nevis, Saint Lucia, Saint Vincent and the Grenadines, Samoa, San Marino, Serbia, Seychelles, Slovenia, Somalia, South Sudan, Sri Lanka, Syrian Arab Republic, Tajikistan, Thailand, The former Yugoslav Republic of Macedonia, Timor-Leste, Tonga, Tunisia, Turkmenistan, Tuvalu, Ukraine, Vanuatu, and Viet Namhave not introduced PCV till April 2016.

Land cover and forest formation distributions for St. Kitts, Nevis, St. Eustatius, Grenada and Barbados from decision tree classification of cloud-cleared satellite imagery

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Helmer, E.H.; Kennaway, T.A.; Pedreros, D.H.; Clark, M.L.; Marcano-Vega, H.; Tieszen, L.L.; Ruzycki, T.R.; Schill, S.R.; Carrington, C.M.S.

2008-01-01

Satellite image-based mapping of tropical forests is vital to conservation planning. Standard methods for automated image classification, however, limit classification detail in complex tropical landscapes. In this study, we test an approach to Landsat image interpretation on four islands of the Lesser Antilles, including Grenada and St. Kitts, Nevis and St. Eustatius, testing a more detailed classification than earlier work in the latter three islands. Secondly, we estimate the extents of land cover and protected forest by formation for five islands and ask how land cover has changed over the second half of the 20th century. The image interpretation approach combines image mosaics and ancillary geographic data, classifying the resulting set of raster data with decision tree software. Cloud-free image mosaics for one or two seasons were created by applying regression tree normalization to scene dates that could fill cloudy areas in a base scene. Such mosaics are also known as cloud-filled, cloud-minimized or cloud-cleared imagery, mosaics, or composites. The approach accurately distinguished several classes that more standard methods would confuse; the seamless mosaics aided reference data collection; and the multiseason imagery allowed us to separate drought deciduous forests and woodlands from semi-deciduous ones. Cultivated land areas declined 60 to 100 percent from about 1945 to 2000 on several islands. Meanwhile, forest cover has increased 50 to 950%. This trend will likely continue where sugar cane cultivation has dominated. Like the island of Puerto Rico, most higher-elevation forest formations are protected in formal or informal reserves. Also similarly, lowland forests, which are drier forest types on these islands, are not well represented in reserves. Former cultivated lands in lowland areas could provide lands for new reserves of drier forest types. The land-use history of these islands may provide insight for planners in countries currently considering

Detection of Leptospiral DNA in the Urine of Donkeys on the Caribbean Island of Saint Kitts

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Bernard Grevemeyer

2017-01-01

Full Text Available Leptospirosis is a global zoonosis caused by pathogenic spirochetes classified within the genus Leptospira. Leptospires live in the proximal renal tubules of reservoir or chronic carrier animals, and are shed in the urine. Naïve animals acquire infection either when they come in direct contact with a reservoir or infected animals or by exposure to environmental surface water or soil that is contaminated with their urine. In this study, urine samples from a herd of donkeys on the Caribbean island of St. Kitts were screened using a TaqMan-based real-time quantitative polymerase chain reaction (qPCR targeting a pathogen-specific leptospiral gene, lipl32. Out of 124 clinically normal donkeys, 22 (18% tested positive for leptospiral DNA in their urine. Water samples from two water troughs used by the donkeys were also tested, but were found to be free from leptospiral contamination. Detection of leptospiral DNA in the urine of clinically healthy donkeys may point to a role that these animals play in the maintenance of the bacteria on St. Kitts.

Detection of Leptospiral DNA in the Urine of Donkeys on the Caribbean Island of Saint Kitts

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Grevemeyer, Bernard; Vandenplas, Michel; Beigel, Brittney; Cho, Ellen; Willingham, Arve Lee; Verma, Ashutosh

2017-01-01

Leptospirosis is a global zoonosis caused by pathogenic spirochetes classified within the genus Leptospira. Leptospires live in the proximal renal tubules of reservoir or chronic carrier animals, and are shed in the urine. Naïve animals acquire infection either when they come in direct contact with a reservoir or infected animals or by exposure to environmental surface water or soil that is contaminated with their urine. In this study, urine samples from a herd of donkeys on the Caribbean island of St. Kitts were screened using a TaqMan-based real-time quantitative polymerase chain reaction (qPCR) targeting a pathogen-specific leptospiral gene, lipl32. Out of 124 clinically normal donkeys, 22 (18%) tested positive for leptospiral DNA in their urine. Water samples from two water troughs used by the donkeys were also tested, but were found to be free from leptospiral contamination. Detection of leptospiral DNA in the urine of clinically healthy donkeys may point to a role that these animals play in the maintenance of the bacteria on St. Kitts. PMID:29056661

A knowledge, attitude and practices study of the issues of climate change/variability impacts and public health in Trinidad and Tobago, and St Kitts and Nevis.

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Rawlins, S C; Chen, A; Rawlins, J M; Chadee, D D; Legall, G

2007-03-01

To determine the level of understanding of the issues of climate change (CC)/variability (CV) and public health by populations of St Kitts and Nevis (SKN) and Trinidad and Tobago (T&T) and to find whether respondents would be willing to incorporate these values into strategies for dengue fever (DF) prevention. Using a cluster sampling system, representative samples of the communities of SKN (227) and T&T (650) were surveyed for responses to a questionnaire document with questions on the impact of climate variability on health, the physical environment, respondents' willingness to utilize climate issues to predict and adapt to climate variability for DF prevention. Data were analyzed by Epi Info. Sixty-two per cent SKN and 55% T&T of respondents showed some understanding of the concept of climate change (CC) and distinguished this from climate variability (CV). With regard to causes of CC, 48% SKN and 50% T&T attributed CC to all of green houses gases, holes in the ozone layer burning of vegetation and vehicular exhaust gases. However some 39.3% SKN and 31% (T&T) did not answer this question. In response to ranking issues of life affected by CC/CV in both countries, respondents ranked them: health > water resources > agriculture > biodiversity > coastal degradation. The major health issues identified for SKN and T&T respondents were: food-borne diseases > water-borne diseases > heat stresses; vector-borne diseases were only ranked 4th and 5th for SKN and T&T respondents respectively. There was in both countries a significant proportion of respondents (p attitudes did not always coincide with practices of using ES for DF prevention, in both countries, even with CC/CV tools of prediction being available, it seems that respondents could be persuaded to use such strategies. There is a need for demonstration of the efficacy of CC/CV information and promotion of its usefulness for community involvement in DF and possibly other disease prevention.

Nevi and pregnancy.

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Bieber, Amy Kalowitz; Martires, Kathryn J; Driscoll, Marcia S; Grant-Kels, Jane M; Pomeranz, Miriam Keltz; Stein, Jennifer A

2016-10-01

Changes in the moles of pregnant women are frequently attributed to pregnancy, but recent studies suggest that pregnancy does not induce significant physiologic changes in nevi. It is common for nevi on the breasts and abdomen to grow with normal skin expansion, but studies that have examined melanocytic nevi on the backs or lower extremities have found no significant changes in size during pregnancy. Several studies have also investigated the belief that moles darken during pregnancy and have found insufficient evidence to support this idea. Dermoscopically, transient changes have been identified, but none are suggestive of melanoma. Results vary in terms of histologic changes seen in samples taken from pregnant women, but all authors agree that any histopathologic features consistent with melanoma should be viewed as melanoma and not attributed to pregnancy. Biopsy specimens should be obtained promptly from any changing mole that would raise concern for malignancy in a nonpregnant patient. Such procedures can be performed safely during pregnancy. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

The association of academic tracking to depressive symptoms among adolescents in three Caribbean countries

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Clarke Nelson

2010-05-01

Full Text Available Abstract Background Students who are tracked into low performing schools or classrooms that limit their life chances may report increased depressive symptoms. Limited research has been conducted on academic tracking and its association with depressive symptoms among high school students in the Caribbean. This project examines levels of depressive symptoms among tenth grade students tracked within and between high schools in Jamaica, St. Vincent and St. Kitts and Nevis. Methods Students enrolled in grade ten of the 2006/2007 academic year in Jamaica, St. Kitts and Nevis and St. Vincent were administered the Beck Depression Inventory II (BDI-II. In Jamaica and St. Vincent, academic tracking was operationalized using data provided by the local Ministries of Education. These Ministries ranked ordered schools according to students' performance on Caribbean school leaving examinations. In St. Kitts and Nevis tracking was operationalized by classroom assignments within schools whereby students were grouped into classrooms according to their levels of academic achievement. Multiple regression analyses were conducted to examine the relationships between academic tracking and BDI-II depression scores. Results A wide cross-section of 4th form students in each nation was sampled (n = 1738; 278 from Jamaica, 737 St. Kitts and Nevis, 716 from St. Vincent; 52% females, 46.2% males and 1.8% no gender reported; age 12 to 19 years, mean = 15.4 yrs, sd = .9 yr. Roughly half (53% of the students reported some symptoms of depression with 19.2% reporting moderate and 10.7% reporting severe symptoms of depression. Students in Jamaica reported significantly higher depression scores than those in either St. Kitts and Nevis or St. Vincent (p Conclusions There appears to be an association between academic tracking and depressive symptoms that is differentially manifested across the islands of Jamaica, St. Kitts and Nevis and St. Vincent.

Molecular analysis of Salmonella enteritidis isolates from the Caribbean by pulsed-field gel electrophoresis

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Abiodun Adesiyun

2000-11-01

Full Text Available Using pulsed-field gel electrophoresis (PFGE, between 1987 and 1996 we analyzed Salmonella enteritidis isolates from gastroenteritis cases in four Caribbean countries: Barbados, Saint Kitts and Nevis, Saint Lucia, and Trinidad and Tobago. We also determined the resistance of the isolates to 12 antimicrobial agents. Of the 129 isolates of S. enteritidis available for testing, DNA digested by XbaI revealed 13 distinctive PFGE patterns. The most prevalent XbaI PFGE patterns were group 1 (88 of 129 isolates, 68.2% and group 2 (26 of 129, 20.2%. The patterns found among S. enteritidis isolates correlated with the geographical origin of the isolates. Of the 28 isolates from Barbados, 20 of them (71.4% belonged to XbaI PFGE group 2, and of the 93 isolates from Trinidad and Tobago, 78 of them (83.9% belonged to group 1. SpeI digestion of S. enteritidis genome was not as discriminatory as XbaI. Overall, of the 129 isolates, 67 of them (51.9% exhibited resistance to one or more of the 12 antimicrobial agents that we tested. The prevalence of resistance was 53.8% for the S. enteritidis isolates tested from Trinidad and Tobago, 50.0% for those from Barbados, 28.6% for those from Saint Lucia, and 100.0% for one isolate from the island of Saint Kitts. Resistance was highest to triple sulfur (59 of 129 isolates, 45.7%, followed by furadantoin (10 of 129, 7.8%, ampicillin (7 of 129, 5.4%, and carbamycin (5 of 129, 3.9%.

Molecular analysis of Salmonella enteritidis isolates from the Caribbean by pulsed-field gel electrophoresis.

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Adesiyun, A; Carson, A; McAdoo, K; Bailey, C

2000-11-01

Using pulsed-field gel electrophoresis (PFGE), between 1987 and 1996 we analyzed Salmonella enteritidis isolates from gastroenteritis cases in four Caribbean countries: Barbados, Saint Kitts and Nevis, Saint Lucia, and Trinidad and Tobago. We also determined the resistance of the isolates to 12 antimicrobial agents. Of the 129 isolates of S. enteritidis available for testing, DNA digested by XbaI revealed 13 distinctive PFGE patterns. The most prevalent XbaI PFGE patterns were group 1 (88 of 129 isolates, 68.2%) and group 2 (26 of 129, 20.2%). The patterns found among S. enteritidis isolates correlated with the geographical origin of the isolates. Of the 28 isolates from Barbados, 20 of them (71.4%) belonged to XbaI PFGE group 2, and of the 93 isolates from Trinidad and Tobago, 78 of them (83.9%) belonged to group 1. SpeI digestion of S. enteritidis genome was not as discriminatory as XbaI. Overall, of the 129 isolates, 67 of them (51.9%) exhibited resistance to one or more of the 12 antimicrobial agents that we tested. The prevalence of resistance was 53.8% for the S. enteritidis isolates tested from Trinidad and Tobago, 50.0% for those from Barbados, 28.6% for those from Saint Lucia, and 100.0% for one isolate from the island of Saint Kitts. Resistance was highest to triple sulfur (59 of 129 isolates, 45.7%), followed by furadantoin (10 of 129, 7.8%), ampicillin (7 of 129, 5.4%), and carbamycin (5 of 129, 3.9%).

Molecular analysis of Salmonella enteritidis isolates from the Caribbean by pulsed-field gel electrophoresis

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Adesiyun Abiodun

2000-01-01

Full Text Available Using pulsed-field gel electrophoresis (PFGE, between 1987 and 1996 we analyzed Salmonella enteritidis isolates from gastroenteritis cases in four Caribbean countries: Barbados, Saint Kitts and Nevis, Saint Lucia, and Trinidad and Tobago. We also determined the resistance of the isolates to 12 antimicrobial agents. Of the 129 isolates of S. enteritidis available for testing, DNA digested by XbaI revealed 13 distinctive PFGE patterns. The most prevalent XbaI PFGE patterns were group 1 (88 of 129 isolates, 68.2% and group 2 (26 of 129, 20.2%. The patterns found among S. enteritidis isolates correlated with the geographical origin of the isolates. Of the 28 isolates from Barbados, 20 of them (71.4% belonged to XbaI PFGE group 2, and of the 93 isolates from Trinidad and Tobago, 78 of them (83.9% belonged to group 1. SpeI digestion of S. enteritidis genome was not as discriminatory as XbaI. Overall, of the 129 isolates, 67 of them (51.9% exhibited resistance to one or more of the 12 antimicrobial agents that we tested. The prevalence of resistance was 53.8% for the S. enteritidis isolates tested from Trinidad and Tobago, 50.0% for those from Barbados, 28.6% for those from Saint Lucia, and 100.0% for one isolate from the island of Saint Kitts. Resistance was highest to triple sulfur (59 of 129 isolates, 45.7%, followed by furadantoin (10 of 129, 7.8%, ampicillin (7 of 129, 5.4%, and carbamycin (5 of 129, 3.9%.

[Balloon cell nevi of the conjunctiva (author's transl)].

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Schlageter, P E; Daicker, B

1975-06-01

The clinical and histological features of three cases of conjunctival balloon cell nevi are described. This peculiar form of nevus is very rare in the conjunctiva. The findings are compared with the descriptions in the literature of dermal balloon cell nevi. They demonstrate, that the conjunctival and dermal tumours are of idential histological structure. The proliferations of the conjunctival epithelium often found in conjunctival nevi do not modify the balloon cell nevi. These can not be diagnosed clinically. The problems of the pathogenesis of the balloon cell nevi are discussed.

The spectrum of dermatoscopic patterns in blue nevi.

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Di Cesare, Antonella; Sera, Francesco; Gulia, Andrea; Coletti, Gino; Micantonio, Tamara; Fargnoli, Maria Concetta; Peris, Ketty

2012-08-01

Blue nevi are congenital or acquired, dermal dendritic melanocytic proliferations that can simulate melanocytic and nonmelanocytic lesions including melanoma, cutaneous metastasis of melanoma, Spitz/Reed nevi, and basal cell carcinoma. We sought to investigate global and local dermatoscopic patterns of blue nevi compared with melanomas and basal cell carcinomas. We retrospectively analyzed global and local features in 95 dermatoscopic images of blue nevi and in 190 melanomas and basal cell carcinomas that were selected as control lesions on the basis of similar pigmentation. Lesion pigmentation was classified as monochromatic, dichromatic, or multichromatic. A global pattern characterized by homogeneous pigmentation was observed in all of 95 (100%) blue nevi. Eighty of 95 (84.2%) blue nevi presented a homogeneous pattern consisting of one color (blue, black, or brown) or two colors (blue-brown, blue-gray, or blue-black). Fifteen of 95 (15.8%) blue nevi had a multichromatic (blue, gray, black, brown, and/or red) pigmentation. In all, 47 of 95 (49.5%) blue nevi were characterized by pigmentation in the absence of pigment network or any other local dermatoscopic features. And 48 of 95 (50.5%) blue nevi showed local dermatoscopic patterns including whitish scarlike depigmentation, dots/globules, vascular pattern, streaks, and networklike pattern. The study was retrospective and involved only Caucasian people of Italian origin. The characteristic feature of blue nevi is a homogeneous pigmentation that is blue, blue-gray, blue-brown, or blue-black. We showed that a wide spectrum of local dermatoscopic features (whitish scarlike depigmentation, dots/globules, peripheral streaks or vessels) may also be present. In such cases, clinical and dermatoscopic distinction from melanoma or nonmelanocytic lesions may be difficult or impossible, and surgical excision is necessary. Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

Clinical and dermoscopic features of nevi in patients with psoriasis

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Ilina Natalia Glebovna

2017-01-01

Full Text Available The aim of the present study is to display the clinical and dermoscopic features of melanocytic nevi of more than 5 mm in diameter in psoriasis patients. A total of 32 patients with psoriasis (21 male, 11 female; average age 37.4 formed the first study group. In 22 patients (68.8%, melanocytic nevi of 5 mm in diameter and bigger (total of 68 nevi were clinically found. For a randomized trial, 100 people (21 male, 79 female; average age 27.8 without psoriasis were invited to form the second study group. Only 37 of them had nevi ≥5 mm in diameter (total of 60 nevi. Complete questionnaire, full body photometric skin examination, dermoscopy examination on the dermatoscope HEINE MINI 10X with 70% ethyl alcohol immersion, skin type identification according to the Fitzpatrick classification, and nevi assessment according to ABCD and ABC rules were obtained for all recruited people. Our study showed that patients with psoriasis are more susceptible to melanocytic nevi of >5 mm in diameter (68.8%, while the result for the second group was 37%. As for nevi of dysplastic criteria, we found 32% in psoriasis patients vs. 42% in the monitoring group. Moreover, we should bear in mind the influencing factors of skin phototype II and artificial insolation (e.g., tanning, PUVA (Psoralen and ultraviolet A, and narrowband phototherapy 311 nm obtained by the patients from the first group.

Chrysalis and negative pigment network in Spitz nevi.

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Botella-Estrada, Rafael; Requena, Celia; Traves, Victor; Nagore, Eduardo; Guillen, Carlos

2012-04-01

Chrysalis, also named shiny white streaks, are white, linear structures only visible with polarized dermoscopy. They have been reported in several tumors included melanomas and Spitz nevi, and their histological substrate is believed to be dermal fibrosis. We have performed a correlation study between the dermoscopic and the histopathological features of 9 Spitz nevi. Chrysalis were present in 4 Spitz nevi (44%) and in all of them there was a high degree of fibroplasia. In one case, chrysalis, evident at the center of the lesion, progressively merged with negative pigment network at the periphery. We suggest that chrysalis and negative pigment network are manifestations of the same histopathological finding: increased collagen occurring at different levels of the dermis.

Sunburn, sun exposure, and sun sensitivity in the Study of Nevi in Children.

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Satagopan, Jaya M; Oliveria, Susan A; Arora, Arshi; Marchetti, Michael A; Orlow, Irene; Dusza, Stephen W; Weinstock, Martin A; Scope, Alon; Geller, Alan C; Marghoob, Ashfaq A; Halpern, Allan C

2015-11-01

To examine the joint effect of sun exposure and sunburn on nevus counts (on the natural logarithm scale; log nevi) and the role of sun sensitivity. We describe an analysis of cross-sectional data from 443 children enrolled in the prospective Study of Nevi in Children. To evaluate the joint effect, we partitioned the sum of squares because of interaction between sunburn and sun exposure into orthogonal components representing (1) monotonic increase in log nevi with increasing sun exposure (rate of increase of log nevi depends on sunburn), and (2) nonmonotonic pattern. In unadjusted analyses, there was a marginally significant monotonic pattern of interaction (P = .08). In adjusted analyses, sun exposure was associated with higher log nevi among those without sunburn (P sunburn (P = .14). Sunburn was independently associated with log nevi (P = .02), even though sun sensitivity explained 29% (95% confidence interval: 2%-56%, P = .04) of its effect. Children with high sun sensitivity and sunburn had more nevi, regardless of sun exposure. A program of increasing sun protection in early childhood as a strategy for reducing nevi, when applied to the general population, may not equally benefit everyone. Copyright © 2015 Elsevier Inc. All rights reserved.

Parenting and depressive symptoms among adolescents in four Caribbean societies

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2012-01-01

Background The strategies that parents use to guide and discipline their children may influence their emotional health. Relatively little research has been conducted examining the association of parenting practices to depressive symptoms among Caribbean adolescents. This project examines the association of parenting styles to levels of depressive symptoms among adolescents in Jamaica, the Bahamas, St. Kitts and Nevis, and St. Vincent. Methods Adolescents attending grade ten of academic year 2006/2007 in Jamaica, the Bahamas, St. Vincent, and St. Kitts and Nevis were administered the Parenting Practices Scale along with the BDI-II. Authoritative, Authoritarian, Permissive and Neglectful parenting styles were created using a median split procedure of the monitoring and nurturance subscales of the Parenting Practices Scale. Multiple regression analyses were used to examine the relationships of parenting styles to depressive symptoms. Results A wide cross-section of tenth grade students in each nation was sampled (n = 1955; 278 from Jamaica, 217 from the Bahamas, 737 St. Kitts and Nevis, 716 from St. Vincent; 52.1% females, 45.6% males and 2.3% no gender reported; age 12 to 19 years, mean = 15.3 yrs, sd = .95 yrs). Nearly half (52.1%) of all adolescents reported mild to severe symptoms of depression with 29.1% reporting moderate to severe symptoms of depression. In general, authoritative and permissive parenting styles were both associated with lower levels of depressive symptoms in adolescents. However, the relationship of parenting styles to depression scores was not consistent across countries (p parenting, caregivers in this study used a mixture of different parenting styles with the two most popular styles being authoritative and neglectful parenting. Conclusions There appears to be an association between parenting styles and depressive symptoms that is differentially manifested across the islands of Jamaica, the Bahamas, St. Kitts and Nevis and St

Parenting and depressive symptoms among adolescents in four Caribbean societies.

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Lipps, Garth; Lowe, Gillian A; Gibson, Roger C; Halliday, Sharon; Morris, Amrie; Clarke, Nelson; Wilson, Rosemarie N

2012-09-21

The strategies that parents use to guide and discipline their children may influence their emotional health. Relatively little research has been conducted examining the association of parenting practices to depressive symptoms among Caribbean adolescents. This project examines the association of parenting styles to levels of depressive symptoms among adolescents in Jamaica, the Bahamas, St. Kitts and Nevis, and St. Vincent. Adolescents attending grade ten of academic year 2006/2007 in Jamaica, the Bahamas, St. Vincent, and St. Kitts and Nevis were administered the Parenting Practices Scale along with the BDI-II. Authoritative, Authoritarian, Permissive and Neglectful parenting styles were created using a median split procedure of the monitoring and nurturance subscales of the Parenting Practices Scale. Multiple regression analyses were used to examine the relationships of parenting styles to depressive symptoms. A wide cross-section of tenth grade students in each nation was sampled (n = 1955; 278 from Jamaica, 217 from the Bahamas, 737 St. Kitts and Nevis, 716 from St. Vincent; 52.1% females, 45.6% males and 2.3% no gender reported; age 12 to 19 years, mean = 15.3 yrs, sd = .95 yrs). Nearly half (52.1%) of all adolescents reported mild to severe symptoms of depression with 29.1% reporting moderate to severe symptoms of depression. In general, authoritative and permissive parenting styles were both associated with lower levels of depressive symptoms in adolescents. However, the relationship of parenting styles to depression scores was not consistent across countries (p parenting, caregivers in this study used a mixture of different parenting styles with the two most popular styles being authoritative and neglectful parenting. There appears to be an association between parenting styles and depressive symptoms that is differentially manifested across the islands of Jamaica, the Bahamas, St. Kitts and Nevis and St. Vincent.

Parenting and depressive symptoms among adolescents in four Caribbean societies

Directory of Open Access Journals (Sweden)

Lipps Garth

2012-09-01

Full Text Available Abstract Background The strategies that parents use to guide and discipline their children may influence their emotional health. Relatively little research has been conducted examining the association of parenting practices to depressive symptoms among Caribbean adolescents. This project examines the association of parenting styles to levels of depressive symptoms among adolescents in Jamaica, the Bahamas, St. Kitts and Nevis, and St. Vincent. Methods Adolescents attending grade ten of academic year 2006/2007 in Jamaica, the Bahamas, St. Vincent, and St. Kitts and Nevis were administered the Parenting Practices Scale along with the BDI-II. Authoritative, Authoritarian, Permissive and Neglectful parenting styles were created using a median split procedure of the monitoring and nurturance subscales of the Parenting Practices Scale. Multiple regression analyses were used to examine the relationships of parenting styles to depressive symptoms. Results A wide cross-section of tenth grade students in each nation was sampled (n = 1955; 278 from Jamaica, 217 from the Bahamas, 737 St. Kitts and Nevis, 716 from St. Vincent; 52.1% females, 45.6% males and 2.3% no gender reported; age 12 to 19 years, mean = 15.3 yrs, sd = .95 yrs. Nearly half (52.1% of all adolescents reported mild to severe symptoms of depression with 29.1% reporting moderate to severe symptoms of depression. In general, authoritative and permissive parenting styles were both associated with lower levels of depressive symptoms in adolescents. However, the relationship of parenting styles to depression scores was not consistent across countries (p  Conclusions There appears to be an association between parenting styles and depressive symptoms that is differentially manifested across the islands of Jamaica, the Bahamas, St. Kitts and Nevis and St. Vincent.

Nevos de tejido conectivo Connective tissue nevi

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RE Achenbach

Full Text Available Comunicamos dos casos de nevo del tejido conectivo, el primero con patrón histológico mixto y el segundo con predominio de alteraciones en las fibras elásticas. No se constataron síndromes ni patología sistémica asociada. Un caso presentó disposición linear y un nevo acrómico asociado.Two cases of connective tissue nevi are reported, one of them with a mixed histopatologic pattern and one with elastin fibers diminished. None of the patients had systemic involvement or associated syndromes. The mixed connective tissue nevi type showed a linear distribution and has associated an acromic nevi.

Knowledge and perception of melanocytic nevi and sunburn in young children.

Science.gov (United States)

Richtig, Erika; Jung, Erika; Asbäck, Katharina; Trapp, Michael; Hofmann-Wellenhof, Rainer

2009-01-01

Understanding the public's perception of nevi and sunburn is crucial to melanoma prevention efforts. We investigated the knowledge and perception of melanocytic nevi and sunburns in 77 children 6 to 10 years old (mean 8.2) in two elementary schools in Styria, Austria. The children were interviewed by specially trained psychologists about the number of their moles and how they felt having them. Additionally questions about sunburn history and sunburn perception were asked. The spontaneous answers of the children were recorded, there were no pregiven answers. Afterwards the children were examined by dermatologists clinically and with dermatoscopes. The 96% of the children could describe a nevus (the term "mole" was translated to "nevus") and 91% did not feel bothered about theirs. Only 26% had noted the appearance of new nevi within the last year. The 67% of all children had at least one sunburn and remembered the clinical features. The 20% of the children knew that sunburns could provoke skin cancer. All children felt comfortable during the clinical and dermatoscopic examination. Children aged from 6 to 10 years know exactly why they had suffered from sunburn, can describe the sunburn and how to avoid it. They do not feel bothered by their nevi and are alert to the appearance of new nevi.

On the interplay of telomeres, nevi and the risk of melanoma.

Directory of Open Access Journals (Sweden)

Clara Bodelon

Full Text Available The relationship between telomeres, nevi and melanoma is complex. Shorter telomeres have been found to be associated with many cancers and with number of nevi, a known risk factor for melanoma. However, shorter telomeres have also been found to decrease melanoma risk. We performed a systematic analysis of telomere-related genes and tagSNPs within these genes, in relation to the risk of melanoma, dysplastic nevi, and nevus count combining data from four studies conducted in Italy. In addition, we examined whether telomere length measured in peripheral blood leukocytes is related to the risk of melanoma, dysplastic nevi, number of nevi, or telomere-related SNPs. A total of 796 cases and 770 controls were genotyped for 517 SNPs in 39 telomere-related genes genotyped with a custom-made array. Replication of the top SNPs was conducted in two American populations consisting of 488 subjects from 53 melanoma-prone families and 1,086 cases and 1,024 controls from a case-control study. We estimated odds ratios for associations with SNPs and combined SNP P-values to compute gene region-specific, functional group-specific, and overall P-value using an adaptive rank-truncated product algorithm. In the Mediterranean population, we found suggestive evidence that RECQL4, a gene involved in genome stability, RTEL1, a gene regulating telomere elongation, and TERF2, a gene implicated in the protection of telomeres, were associated with melanoma, the presence of dysplastic nevi and number of nevi, respectively. However, these associations were not found in the American samples, suggesting variable melanoma susceptibility for these genes across populations or chance findings in our discovery sample. Larger studies across different populations are necessary to clarify these associations.

High frequency of PTEN mutations in nevi and melanomas from xeroderma pigmentosum patients.

Science.gov (United States)

Masaki, Taro; Wang, Yun; DiGiovanna, John J; Khan, Sikandar G; Raffeld, Mark; Beltaifa, Senda; Hornyak, Thomas J; Darling, Thomas N; Lee, Chyi-Chia R; Kraemer, Kenneth H

2014-05-01

We examined nevi and melanomas in 10 xeroderma pigmentosum (XP) patients with defective DNA repair. The lesions had a lentiginous appearance with markedly increased numbers of melanocytes. Using laser capture microdissection, we performed DNA sequencing of 18 benign and atypical nevi and 75 melanomas (melanoma in situ and invasive melanomas). The nevi had a similar high frequency of PTEN mutations as melanomas [61% (11/18) versus 53% (39/73)]. Both had a very high proportion of UV-type mutations (occurring at adjacent pyrimidines) [91% (10/11) versus 92% (36/39)]. In contrast to melanomas in the general population, the frequency of BRAF mutations (11%, 7/61), NRAS mutations (21%, 13/62), and KIT mutations (21%, 6/28) in XP melanomas was lower than for PTEN. Phospho-S6 immunostaining indicated activation of the mTOR pathway in the atypical nevi and melanomas. Thus, the clinical and histological appearances and the molecular pathology of these UV-related XP nevi and melanomas were different from nevi and melanomas in the general population. © 2014 Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

Improvements to science operations at Kitt Peak National Observatory

Science.gov (United States)

Bohannan, Bruce

1998-07-01

In recent years Kitt Peak National Observatory has undertaken a number of innovative projects to optimize science operations with the suite of telescopes we operate on Kitt Peak, Arizona. Changing scientific requirements and expectations of our users, evolving technology and declining budgets have motivated the changes. The operations improvements have included telescope performance enhancements--with the focus on the Mayall 4-m--modes of observing and scheduling, telescope control and observing systems, planning and communication, and data archiving.

A hypothesis on the morphologic differences between Unna and Miescher nevi on the head and neck, based on embryologic bases.

Science.gov (United States)

Fernandez-Flores, Angel; Sanchez-Velicia, Laura; Manjon, Juan A; Alija, Antonio; Soto, Francisco

2012-08-01

Unna and Miescher nevi show very different morphologic features. The main difference is that melanocytes involve mainly the papillary dermis in Unna nevi, whereas they widely penetrate the reticular dermis in Miescher nevi. The reason for this behavior is not totally understood, but anatomical location might play a role, since because Unna nevi are mainly found on the trunk, whereas Miescher nevi are mainly found on the face. We decided to test this hypothesis in relative easy way: dermis from the frontal, temporal, maxillary, and mandibullary regions derives from the neural crest, whereas the dermis of the parietal/occipital regions originates from the paraxial mesoderm (somites and somitomeres). Therefore, we studied the morphology of 137 acquired melanocytic nevi from the head and neck and classified their locations in 7 areas: occipital, temporal, parietal, frontal, face, high neck, and low neck. From such areas, we distinguished 4 groups: area A (parietal + occipital + low neck); area B (face + temporal + frontal + high neck); area 1 (parietal and occipital); and area 2 (temporal and frontal). In region A, 97.30% of the nevi were of Unna type. In region B, 89.00% were of Miescher type. Region A had 76.60% of Unna type nevi, whereas region B had 98.89% of Miescher nevi. In area 1, 100% of the nevi were of Miescher type. In area 2, 86.67% of the nevi were of Unna type. Region 1 had 86.67% of the cranial Unna nevi, whereas region 2 had 100% of the cranial Miescher nevi. Moreover, 90.9% of the nevi from the low neck were of Unna type. In the high neck, 20% of nevi were of Unna type. Finally, 90.90% of Unna nevi were in the low neck, whereas 80% of Miescher nevi were in the high neck. We concluded that these findings supported the hypothesis that the embryologic differences of these areas of head and neck might play a role in the morphology of Unna and Miescher nevi.

Oncogenic mutations in melanomas and benign melanocytic nevi of the female genital tract.

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Tseng, Diane; Kim, Julie; Warrick, Andrea; Nelson, Dylan; Pukay, Marina; Beadling, Carol; Heinrich, Michael; Selim, Maria Angelica; Corless, Christopher L; Nelson, Kelly

2014-08-01

The genetic heterogeneity of melanomas and melanocytic nevi of the female genital tract is poorly understood. We aim to characterize the frequency of mutations of the following genes: BRAF, NRAS, KIT, GNA11, and GNAQ in female genital tract melanomas. We also characterize the frequency of BRAF mutations in female genital tract melanomas compared with melanocytic nevi. Mutational screening was performed on the following female genital tract melanocytic neoplasms: 25 melanomas, 7 benign melanocytic nevi, and 4 atypical melanocytic nevi. Of the 25 female genital tract melanoma specimens queried, KIT mutations were detected in 4 (16.0%), NRAS mutations in 4 (16.0%), and BRAF mutations in 2 (8.0%) samples. Two of the tumors with KIT mutations harbored double mutations in the same exon. No GNAQ or GNA11 mutations were identified among 11 melanomas screened. BRAF V600E mutations were detected in 7 of 7 benign melanocytic genital nevi (100%) and 3 of 4 atypical genital nevi (75%). Our study is limited by the small sample size of this rare subset of melanomas. KIT, NRAS, and BRAF mutations are found in a subset of female genital tract melanomas. Screening for oncogenic mutations is important for developing and applying clinical therapies for melanomas of the female genital tract. Copyright © 2014 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

Dermoscopic patterns of melanocytic nevi in children and adolescents: a cross-sectional study*

Science.gov (United States)

Piazza, Christiane Donato; Yamada, Sergio; Marcassi, Aline P; Maciel, Marina G; Seize, Maria P; Cestari, Silmara C P

2017-01-01

Background Childhood is a dynamic period regarding nevogenesis. Dermoscopy is a noninvasive technique, recommended for the evaluation of pigmented cutaneous lesions. Objectives The purpose of this study was to describe the structures and dermoscopic patterns of melanocytic nevi observed in children and adolescents. Methods Dermoscopy with photographic documentation was used for nevi located on the face, trunk, and extremities of 38 patients aged from one to 16 years examined at the Pediatric Dermatology Outpatient Clinic of the Federal University of São Paulo. Results The study included 201 skin lesions that were diagnosed as nevi during clinic examination. Upon evaluation of the global dermoscopic pattern of the lesions, the most frequently observed nevi were reticular (39.0%), followed by homogeneous (23.9%) and globular nevi (16.4%). During evaluation of the dermoscopic structures, according to the body site, the pigment network was the most observed in the extremities. Study limitations A limitation to be considered is that the inclusion of small or new lesions may hinder the differentiation between dots and globules. Conclusions In our study, the most observed pattern was reticular. There was a difference in the predominance of structures dependent on the anatomical location. PMID:29186245

Connecting Productivity, Nutrition and Health

International Development Research Centre (IDRC) Digital Library (Canada)

Because animal protein is an integral part of a diverse diet, the project ... sufficient to feed 70 animals. The project has ... ability to address food security and health problems related to ... St. Kitts and Nevis: Ministry of Agriculture and Marine.

Saints and Sainthood

DEFF Research Database (Denmark)

Bandak, Andreas

2018-01-01

Saints are central for personal devotion, as intercessors and mediators between humanity and God, and as models for emulation. Relationships with and images of saints and holy figures are by no means fixed, but have developed, mirrored and challenged different times and cultures. Sainthood is a p...... with him or her even if they never aspire to become a saint themselves. In this sense sainthood is a matter of social relationships—relationships which are perennially in the making....

GI Locator Service

Science.gov (United States)

... LIBERIA LIBYA LIECHTENSTEIN LITHUANIA LUXEMBOURG MACAO MADAGASCAR MALAWI MALAYSIA MALDIVES MALI MALTA MARIANA ISLANDS MARSHALL ISLANDS Martinique ... OF KOREA REPUBLIC OF MACEDONIA REUNION ROMANIA RUSSIAN FEDERATION RWANDA SAINT BARTHéLEMY SAINT HELENA SAINT KITTS AND ...

PREP KITT, System Reliability by Fault Tree Analysis. PREP, Min Path Set and Min Cut Set for Fault Tree Analysis, Monte-Carlo Method. KITT, Component and System Reliability Information from Kinetic Fault Tree Theory

International Nuclear Information System (INIS)

Vesely, W.E.; Narum, R.E.

1997-01-01

1 - Description of problem or function: The PREP/KITT computer program package obtains system reliability information from a system fault tree. The PREP program finds the minimal cut sets and/or the minimal path sets of the system fault tree. (A minimal cut set is a smallest set of components such that if all the components are simultaneously failed the system is failed. A minimal path set is a smallest set of components such that if all of the components are simultaneously functioning the system is functioning.) The KITT programs determine reliability information for the components of each minimal cut or path set, for each minimal cut or path set, and for the system. Exact, time-dependent reliability information is determined for each component and for each minimal cut set or path set. For the system, reliability results are obtained by upper bound approximations or by a bracketing procedure in which various upper and lower bounds may be obtained as close to one another as desired. The KITT programs can handle independent components which are non-repairable or which have a constant repair time. Any assortment of non-repairable components and components having constant repair times can be considered. Any inhibit conditions having constant probabilities of occurrence can be handled. The failure intensity of each component is assumed to be constant with respect to time. The KITT2 program can also handle components which during different time intervals, called phases, may have different reliability properties. 2 - Method of solution: The PREP program obtains minimal cut sets by either direct deterministic testing or by an efficient Monte Carlo algorithm. The minimal path sets are obtained using the Monte Carlo algorithm. The reliability information is obtained by the KITT programs from numerical solution of the simple integral balance equations of kinetic tree theory. 3 - Restrictions on the complexity of the problem: The PREP program will obtain the minimal cut and

The Burning Saints

DEFF Research Database (Denmark)

Xygalatas, Dimitris

. Carrying the sacred icons of the saints, participants dance over hot coals as the saint moves them. The Burning Saints presents an analysis of these rituals and the psychology behind them. Based on long-term fieldwork, The Burning Saints traces the historical development and sociocultural context......, The Burning Saints presents a highly original analysis of how mental processes can shape social and religious behaviour....

Number and size of acquired melanocytic nevi and affecting risk factors in cases admitted to the dermatology clinic

Directory of Open Access Journals (Sweden)

Ayşegül Yalçınkaya İyidal

2016-10-01

Full Text Available Introduction: The size and number of acquired melanocytic nevi (AMN and presence of dysplastic nevi are the leading risk factors that should be recognized in the development of malignant melanoma. Aim: To evaluate AMN and risk factors in the development of AMN in all age groups admitted to a dermatology outpatient clinic. Material and methods : Four hundred and twelve patients who were admitted to the dermatology outpatient clinic for any dermatological symptom and who accepted to participate in the study were randomly included in the study. For each case, background-family history and dermatological findings were recorded. All AMN observed in the patients were dermatoscopically examined. Results : The presence of more than 50 nevi was significantly higher in males, in individuals who had a history of sunburn and smokers. The number of nevi that were 5 mm and below was found to be higher in individuals who regularly sunbathed their face/body, in individuals using sunscreen, in individuals who had a history of sunburn, smokers and alcohol users. The number of nevi that were above 5 mm was higher in smokers. The total dermatoscopy score between 4.75 and 5.45 was found to be higher in individuals who had more than 50 nevi, in individuals exposed to more than one chemical substance and in alcohol users. Conclusions : When determining the patient’s risk factors, factors such as the patient’s sunbathing habits and chemical substance exposure features should be taken into consideration besides the number and size of nevi.

Melanocytic Nevi and Sun Exposure in a Cohort of Colorado Children: Anatomic Distribution and Site-Specific Sunburn

Science.gov (United States)

Dodd, Athena T.; Morelli, Joseph; Mokrohisky, Stefan T.; Asdigian, Nancy; Byers, Tim E.; Crane, Lori A.

2010-01-01

Sun exposure and high prevalence of melanocytic nevi are major risk factors for melanoma, but the relationship between them is not well understood. This study examines the relationship between sun exposure (detailed by anatomic location and history of site-specific sunburns) and the presence of melanocytic nevi on 743 White children in Denver, Colorado. Parental reports of site-specific sunburns were collected annually for 2 years starting at ages 5 to 6 years. In the third year, nevi were counted and mapped by anatomic location. Nevus density was higher for boys (36.0 nevi/m2) than for girls (31.0 nevi/m2; P = 0.04). Nevus density was highest on the face, neck, and lateral forearms and was significantly higher in chronically versus intermittently sun-exposed areas (P sunburn. The face, shoulders, and back were the most frequently sunburned areas of the body. When adjusted for host factors, total number of sunburns was significantly associated with higher total nevus prevalence (P = 0.01 for one burn). Site-specific sunburns were significantly associated with nevus prevalence on the back (P = 0.03 for three or more sunburns), but not on the face, arms, or legs. In this high-risk population, there is evidence for two pathways to nevus accumulation: by chronic sun exposure and by intermittent exposure related to sunburns. PMID:17932362

Genomic copy number analysis of a spectrum of blue nevi identifies recurrent aberrations of entire chromosomal arms in melanoma ex blue nevus.

Science.gov (United States)

Chan, May P; Andea, Aleodor A; Harms, Paul W; Durham, Alison B; Patel, Rajiv M; Wang, Min; Robichaud, Patrick; Fisher, Gary J; Johnson, Timothy M; Fullen, Douglas R

2016-03-01

Blue nevi may display significant atypia or undergo malignant transformation. Morphologic diagnosis of this spectrum of lesions is notoriously difficult, and molecular tools are increasingly used to improve diagnostic accuracy. We studied copy number aberrations in a cohort of cellular blue nevi, atypical cellular blue nevi, and melanomas ex blue nevi using Affymetrix's OncoScan platform. Cases with sufficient DNA were analyzed for GNAQ, GNA11, and HRAS mutations. Copy number aberrations were detected in 0 of 5 (0%) cellular blue nevi, 3 of 12 (25%) atypical cellular blue nevi, and 6 of 9 (67%) melanomas ex blue nevi. None of the atypical cellular blue nevi displayed more than one aberration, whereas complex aberrations involving four or more regions were seen exclusively in melanomas ex blue nevi. Gains and losses of entire chromosomal arms were identified in four of five melanomas ex blue nevi with copy number aberrations. In particular, gains of 1q, 4p, 6p, and 8q, and losses of 1p and 4q were each found in at least two melanomas. Whole chromosome aberrations were also common, and represented the sole finding in one atypical cellular blue nevus. When seen in melanomas, however, whole chromosome aberrations were invariably accompanied by partial aberrations of other chromosomes. Three melanomas ex blue nevi harbored aberrations, which were absent or negligible in their precursor components, suggesting progression in tumor biology. Gene mutations involving GNAQ and GNA11 were each detected in two of eight melanomas ex blue nevi. In conclusion, copy number aberrations are more common and often complex in melanomas ex blue nevi compared with cellular and atypical cellular blue nevi. Identification of recurrent gains and losses of entire chromosomal arms in melanomas ex blue nevi suggests that development of new probes targeting these regions may improve detection and risk stratification of these lesions.

Melanocytic lesions in a private pathology practice. Comparison of histologic features in different tumor types with particular reference to dysplastic nevi.

Science.gov (United States)

Hastrup, N; Hou-Jensen, K

1993-11-01

This study reviews a total of 1000 melanocytic lesions--two separate 500 consecutive sample groupings from 1980 and 1989, respectively--diagnosed in a private non-hospital-associated pathology practice. Lesions were classified as lentigo simplex, congenital nevus, "common" nevus, dysplastic nevus, blue nevus, Spitz's nevus or malignant melanoma. A comparison of the two periods reveals an increase in dysplastic nevi from one in 1980 to nine in 1989. The histologic changes in these nevi were compared to those of the other tumors. Pronounced cytologic atypia was seen in the melanocytes of a few "common" nevi, but more often in the dysplastic nevi and in all of the melanomas. Slight nuclear atypia was usual in "common" nevi and lentigines, and also fibroplasia, lymphocytic infiltration, vessel proliferation and pigment incontinence were seen in both "common" nevi and dysplastic nevi. It is concluded that no single histologic variable was specific for dysplastic nevi.

En Face Optical Coherence Tomography Angiography Imaging Versus Fundus Photography in the Measurement of Choroidal Nevi.

Science.gov (United States)

Lee, Michele D; Kaidonis, Georgia; Kim, Alice Y; Shields, Ryan A; Leng, Theodore

2017-09-01

Choroidal nevi are common benign intraocular tumors with a small risk of malignant transformation. This retrospective study investigates the use of en face spectral-domain optical coherence tomography angiography (SD-OCTA) in determining the clinical features and measurement of choroidal nevi. Patients with choroidal nevi were imaged with both OCTA and a fundus photography device. Greatest longitudinal dimension (GLD), perpendicular dimension (PD), and the GLD/PD ratio were assessed on each device. Inter-device variation and intra- and inter-rater reliability analyses were performed. Fourteen patients with choroidal nevi were included. No significant difference between the GLD/PD ratio as measured by all three devices was found (Chi-square = 2.8, 2 df, P = .247). Intraclass correlation coefficients were greater than 0.7 for repeated measures on all devices, suggesting good repeatability and reproducibility. This study demonstrated inter-device consistency and high intra- and inter-rater reliability when measuring choroidal nevi. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:741-747.]. Copyright 2017, SLACK Incorporated.

Saints and Sainthood around the Baltic Sea

DEFF Research Database (Denmark)

This collection of articles covers most of the Baltic Region with a special focus on the cult of saints in Russia, Prussia, Finland, Sweden, Denmark, Estonia and Latvia (more commonly referred to in the Middle Ages as Livonia). The articles cover a wide range of topics, for example the introduction...... of foreign (and ‘old’) saints into new regions, the creation of new local cults of saints in newly Christianized regions, the role of the cult of saints in the creation of political and lay identities, the adaption of the cult of saints in folk poetry and the potential role of saints in times of war...

Aberrant expression of HMB-45 in traumatized melanocytic nevi.

Science.gov (United States)

Leleux, Todd M; Prieto, Victor G; Diwan, A Hafeez

2012-09-01

Assessment of histologic and immunohistochemical maturation (with HMB-45 and anti-Ki-67) may be helpful in differentiating benign melanocytic nevi (BMN) from malignant melanoma. Recently, we reported loss of maturation and aberrant immunohistochemical findings in melanocytic nevi after liquid nitrogen cryotherapy (Adeniran et al, J Am Acad Dermatol 2009;61:341-5). Herein we report a similar phenomenon identified in traumatized melanocytic nevi (TMN). We sought to evaluate the histologic and immunohistochemical findings in early and late stages of traumatized nevi. Twenty-four cases of TMN were retrieved from the pathology archives. These were then assessed by two pathologists (T.L. and A.H.D.) using HMB-45 and MIB-1 (for Ki-67) antibodies. TMN showed some of the following findings: epidermal changes (parakeratosis, ulceration, serum crust, flattening of the epidermis) and dermal changes including fibrosis and the presence of melanophages. In some cases, there was architectural disorder of the overlying melanocytes, with crowding in the basal layer, but without significant pagetoid spread. Occasionally, the dermal scar contained larger, more epithelioid-appearing melanocytes than those beneath the scar. Fifty-four percent of TMN lacked obvious immunohistochemical maturation with HMB-45, since nevus cells within the scar or directly beneath it were strongly labeled. None of the TMN showed appreciable labeling for Ki-67. The exact clinical duration between trauma and biopsy could not be determined. Loss of maturation with HMB-45 in TMN can be a diagnostic pitfall in challenging cases. Concurrent evaluation of MIB-1 expression, along with the characteristic histologic features of trauma, should allow the correct diagnosis to be reached. Copyright © 2011 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

St. René: the Patron Saint of Anaesthetists and a Patron Saint of Canada.

Science.gov (United States)

Calverley, R K

1980-01-01

René Goupil, the Patron Saint of Anaesthetists, and a Patron Saint of Canada, was born in Angers, France in 1608 and studied surgery. He joined the Jesuits as a donné or volunteer worker in 1640 and served in the then tiny colony of Quebec as one of the first medical workers of Canada. After earning meritorious praise for his skills, he again volunteered to attend the Hurons at Sainte Marie, a mission far beyond the frontiers. René's canoe party was ambushed. He was captured by the Mohawks and endured eight weeks of cruel torture before being killed on September 29, 1642. René was the first of eight North American martyrs whose dedication was recognized by canonization in 1930. St. René was appointed Patron Saint of Anaesthetists in 1951.

EAARL-B Submerged Topography - Saint Croix and Saint Thomas, U.S. Virgin Islands, 2014

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Binary point-cloud data for part of the submerged environs of Saint Croix and Saint Thomas, U.S. Virgin Islands, were produced from remotely sensed, geographically...

[Clinical aspects and therapy of lymphangiomas, hemangiomas and nevi in the area of the head and neck].

Science.gov (United States)

Drepper, H

1985-07-01

The superficial angiomas and nevi arise from the endothelial cells, the pigment-cell-system or the epidermal cells. Hemangiomas are benign tumours of the endothelial cells appearing predominantly in female newborn infants. Depending on localisation, growth and proliferation there is a tendency for spontaneous involution. For irreversible dysfunction or anatomical deformities surgical resection during the growth phase of the hemangioma is indicated. Surgery may be necessary to improve the functional and esthetic appearance after spontaneous involution causing loose residual skin. Radiotherapy of the lesion is rarely indicated. Systemic steroid therapy in cooperation with the pediatrician should be reserved only for desperate cases such as Kasabach-Merrit-Syndrome. Port wine nevi without scars can be covered with skin tanning cosmetics. Argon-Laser-Therapy is not yet so selective that healing can be achieved with certainty and without scars. Clinical progression requires surgery, especially for racemose angiectasia. Arterial embolization should only be used under special conditions, and then only as pretreatment. Lymphangiomas are mostly angiectatic processes, especially of lymphatic vascular tissue and vessels. Even large cystic lymphangiomas can be treated quite well by surgery, but operations on large diffuse invasive lymphangiomas often cause lymphedema and infection similar to erysipelas leading to pseudorecurrence. The benign malformations of the pigment cell system require clear differentiation from malignant melanoma and its precursors. Malignant melanoma develops more frequently from congenital nevi of the deep type than from other pigmented lesions. Malignant melanomas arising from giant nevi are usually diagnosed too late so that almost all patients die. Removal of giant nevi as early as possible is recommended. The epidermal malformations, too, need accurate diagnosis. Multisymptomatic syndromes such as the Basal-Cell-Nevus-Syndrome, and vascular and

Oral melanocytic nevi: Report of two cases with immunohistochemical elaboration of their probable origin and maturation

Directory of Open Access Journals (Sweden)

Dipti Dutta

2015-01-01

Full Text Available Oral melanocytic nevi are localized developmental tissue malformations of nevus cells in the oral mucosa. Relatively rare in occurrence compared to their dermal counterparts, considerable debate exists in the literature related to their origin, development and maturation, and their relationship to oral melanocytes.We report two cases of oral melanocytic nevi with classical clinical presentation. The histopathology was consistent with the known patterns of oral melanocytic nevi. Special stains such as Masson Fontana, further substantiated the observation. S-100 and HMB-45 were applied to immunohistochemically elaborate the cell population. Interestingly two distinct cell populations were detected in the lesions. "Type A" cells in the center of the lesion were S-100 positive, indicating a neural origin and immaturity in development, while peripheral "type B" cells stained positive with HMB-45, indicating melanocytic origin and mature development.

Intimate Enemies: French and English Settlers and Commentators in Colonial St. Kitts

Directory of Open Access Journals (Sweden)

Zacek, Natalie A.

2015-04-01

Full Text Available This article examines a variety of texts produced by the French and English colonists of the island of St Kitts in the seventeenth and eighteenth centuries. During this time, the island was jointly settled by these two groups, a situation which created considerable tension and frequent hostilities between them. By placing these texts in dialogue with one another, we gain a clearer and more nuanced understanding of the extent to which these competing imperial projects resembled and differed from one another, allowing us a new perspective on European settlement in the Caribbean in the era of slavery.Este artículo examina la variedad de textos producida por los colonos franceses e ingleses de la isla de St. Kitts (San Cristóbal en los siglos XVII y XVIII, momento en que ambas comunidades se hallaban asentadas en este mismo territorio lo que generó mucha tensión y enfrentamientos frecuentes. La puesta en diálogo de estos textos permite entender las similitudes y diferencias entre los dos proyectos imperiales y ofrece una nueva perspectiva del asentamiento europeo en el Caribe en la época de la esclavitud.

Search Results | Page 920 | IDRC - International Development ...

International Development Research Centre (IDRC) Digital Library (Canada)

Results 9191 - 9200 of 9602 ... Promoting positive dietary behaviours among women and children for ... Report on some aspects of food security policy interventions ... School feeding in St Kitts and Nevis and Trinidad and Tobago ... practices that advance women''s rights and gender equality in state and non-state sectors?

Body Image and Body Type Preferences in St. Kitts, Caribbean: A Cross-Cultural Comparison with U.S. Samples regarding Attitudes towards Muscularity, Body Fat, and Breast Size

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Peter B. Gray

2012-07-01

Full Text Available We investigated body image in St. Kitts, a Caribbean island where tourism, international media, and relatively high levels of body fat are common. Participants were men and women recruited from St. Kitts (n = 39 and, for comparison, U.S. samples from universities (n = 618 and the Internet (n = 438. Participants were shown computer generated images varying in apparent body fat level and muscularity or breast size and they indicated their body type preferences and attitudes. Overall, there were only modest differences in body type preferences between St. Kitts and the Internet sample, with the St. Kitts participants being somewhat more likely to value heavier women. Notably, however, men and women from St. Kitts were more likely to idealize smaller breasts than participants in the U.S. samples. Attitudes regarding muscularity were generally similar across samples. This study provides one of the few investigations of body preferences in the Caribbean.

Comparative study between fundus autofluorescence and red reflectance imaging of choroidal nevi using ultra-wide-field scanning laser ophthalmoscopy.

Science.gov (United States)

Zapata, Miguel Angel; Leila, Mahmoud; Teixidor, Teresa; Garcia-Arumi, Jose

2015-06-01

To explore the utility of fundus autofluorescence (FAF) and red reflectance (RR) imaging using ultra-wide-field scanning laser ophthalmoscope in choroidal nevi. Retrospective observational case study reviewing clinical data, color, FAF, and RR images of patients with choroidal nevi and comparing the findings. The ultra-wide-field scanning laser ophthalmoscope uses green laser 532 nm and red laser 633 nm that enabled FAF and RR imaging, respectively in separate channels. Superimposition of both images yielded a composite color image. The study included 46 eyes of 45 patients. Nevi were unilateral in 44 patients (98%). Forty-one nevi (89.1%) were located temporally between the macula and the equator. All nevi (100%) were deeply pigmented. The most frequent surface changes were lipofuscin pigments, zones of retinal pigment epithelium atrophy, and retinal pigment epithelium pigment clumps in 31 (67.3%), 18 (39.1%), and 8 eyes (17.3%), respectively. Color photographs were superior to FAF in detecting nevus boundaries and surface changes. Red reflectance correlated strongly with color images, although the nevus boundaries and surface changes were better delineated in RR mode. Red reflectance was superior to FAF in delineating the boundaries and surface changes of the nevus; clear visibility (3+) for RR versus no or poor visibility (0/1+) for FAF. Nevertheless, the areas of retinal pigment epithelium atrophy were better delineated in FAF mode; clear visibility (3+) for FAF versus poor visibility (1+) for FAF. Red reflectance imaging is more sensitive than conventional photography for follow-up of choroidal nevi. Fundus autofluorescence should be considered only as a complementary tool to RR imaging.

Reported cases of selected diseases.

Science.gov (United States)

1994-06-01

The number of reported cases of measles, poliomyelitis, tetanus, diphtheria, and whooping cough for the period of January 1, 1994 to the date of the last report is presented in tabular form by country with a comparison for the same epidemiological period in 1993. The countries included are Bolivia, Colombia, Ecuador, Peru, Venezuela, Argentina, Chile, Paraguay, Uruguay, Brazil, Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, Panama, Mexico, Cuba, Haiti, the Dominican Republic, Antigua and Barbuda, the Bahamas, Barbados, Dominica, Grenada, Guyana, Jamaica, Saint Kitts and Nevis, Saint Vincent, Saint Lucia, Suriname, Trinidad and Tobago, Canada, and the US. The figures for measles are given as reported and as confirmed. In some countries, the reported number of cases of measles decreased from 1993 figures (Venezuela 5275 vs. 6060, Paraguay 26 vs. 958, Brazil 272 vs. 958, Canada 30 vs. 38), but, in others, the figure increased from 1993 (Mexico 47 vs. 21, the US 155 vs. 86). There were no reported cases of poliomyelitis for either year in any country. The figures for tetanus are divided into nonneonatal and neonatal. In Brazil the number of nonneonatal cases decreased to 360 from 371 in 1993, and the number of neonatal cases decreased to 28 from 65. In Mexico, nonneonatal cases decreased to 28 from 45, but neonatal cases increased to 23 from 20 in 1993. The number of cases of diphtheria cases in Brazil decreased to 28 from 65 in the same period of 1993. The number of cases of whooping cough decreased to 431 from 1651 in Brazil and to 51 from 70 in Mexico. However, the number of cases in Canada increased to 1047 from 784.

Two African Saints in Medieval Germany.

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Grimm, Reinhold

1992-01-01

The origin and development of two African saints are discussed: Saint Maurice, patron saint of the eastern empire of Otto I; and Caspar, the youngest of the three Magi. Their representation in German art is described and illustrated. (Author/LB)

Evaluation of Sun Protection Habits and Melanocytic Nevi of Population Screened in a Shopping Mall in Ankara

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Banu Öztürk

2009-12-01

Full Text Available Background and Design: The evaluation of sun protection habits, numbers and types of nevi in our community. Material and Method: A stand was built in a big mall in Ankara where 764 patients were screened for the presence of nevi in three working day periods during the month of May of 2005 and 2006. Lesions were evaluated with the help of digital dermatoscopy. In the study, sun protective practices, sunscreen using habits, dermatoscopic diagnosis of the lesions, numbers and the localization of the lesions were also recorded. Results: The study population consisted of 764 patients (438 female, 326 male with age ranging from 1 to 80 (33.7±13.7 years. 55.6% of them had skin type III, 47.3% had sunburn history. Most of the patients (44.1% were not using sunscreens. Hats and umbrellas (40.3% were the most common accessories used for protection. 904 lesions of 764 patients examined by dermatoscopy revealed that the most common diagnosis was nevi. Two patients were diagnosed with having cutaneous melanoma or basal cell carcinoma. Conclusion: Our findings have shown that the general population is not aware of the risks of sun exposure or the appropriate ways for sun protection and that there is a necessity for educational programmes or campaigns about sun protection and nevi in our general population.

Diversity in local food production combats obesity in the Caribbean ...

International Development Research Centre (IDRC) Digital Library (Canada)

26 avr. 2016 ... In response, the Farm to Fork project—a multisector, integrated approach to food and nutrition security in the Caribbean—worked with smallholder farmers in St Kitts-Nevis and Trinidad and Tobago, and in Guyana and St Lucia to develop year-round production of fruit and vegetables to supply the national ...

Parenting and depressive symptoms among adolescents in four Caribbean societies

OpenAIRE

Lipps, Garth; Lowe, Gillian A; Gibson, Roger C; Halliday, Sharon; Morris, Amrie; Clarke, Nelson; Wilson, Rosemarie N

2012-01-01

Abstract Background The strategies that parents use to guide and discipline their children may influence their emotional health. Relatively little research has been conducted examining the association of parenting practices to depressive symptoms among Caribbean adolescents. This project examines the association of parenting styles to levels of depressive symptoms among adolescents in Jamaica, the Bahamas, St. Kitts and Nevis, and St. Vincent. Methods Adolescents attending grade ten of academ...

Combining sound science, legal action and stakeholder involvement to protect a vulnerable coastal aquifer on the island of St. Kitts

Science.gov (United States)

Sahely, H.; Nettles, S.; Burrowes, R.; Haas, G.

2011-12-01

Water resources in small island developing states (SIDS), especially those in the Caribbean are among the most vulnerable systems to human activities and climate change. This vulnerability is exacerbated by a fragmented approach to water resources management. The unconfined coastal aquifer underlying the Basseterre Valley is a significant asset for the people of St. Kitts-Nevis. The potable water extracted from this aquifer represents over 40% of the total water supply for St. Kitts. The area is subject to urban encroachment, inappropriate land use and threats from pollution. A project was implemented using an integrated approach to help government and communities take practical actions to protect this vulnerable aquifer by demonstrating proper management on three fronts: mitigation of threats from contaminants, protection of the aquifer and improved water resources management. The project is funded by the Global Environment Facility (GEF) as part of the Integrating Watershed and Coastal Areas Management (IWCAM) project for Caribbean Small Island States. A comprehensive hydrogeologic evaluation of the aquifer was undertaken in order to aid in the development of a water resources management strategy for the Basseterre Valley Aquifer. Multi-electrode electrical resistivity (MER), a novel surface geophysical technique, was used to delineate the thickness and distribution of sediments throughout the aquifer, zones of increased porosity, zones of possible contamination and the fresh/salt water interface. Together with slowly declining static water levels and elevated dissolved solids levels, the early stages of salt water intrusion have been documented. Groundwater modelling suggests that adjusting the pumping regime, redeveloping some of the existing wells and relocating other wells is a viable option for increasing efficiency and preventing long term dewatering. Overall, the study has provided a wealth of new information about the aquifer for a reasonable cost. A

Église Saint-Pierre-Saint-Paul, Appoigny (Yonne

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Fabrice Henrion

2009-09-01

Full Text Available L’église Saint-Pierre-Saint-Paul d’Appoigny témoigne d’un important chantier du début du XIIIe siècle , mais les sources permettent d’envisager la présence d’un sanctuaire au moins depuis l’extrême fin du VIe siècle. En effet, le règlement liturgique établit par Aunaire, évêque d’Auxerre de 561 à 604, mentionne Epponiacus dans la liste des sanctuaires auxerrois, sans que le vocable de l’église d’Appoigny ne soit précisé. Par ailleurs, depuis au moins le IXe siècle, une tradition, reprise par ...

75 FR 38718 - Safety Zone; Sault Sainte Marie 4th of July Fireworks, St. Mary's River, Sault Sainte Marie, MI

Science.gov (United States)

2010-07-06

... temporary safety zone on the St. Mary's River, Sault Sainte Marie, Michigan. This zone is intended to..., St. Mary's River, Sault Sainte Marie, MI (a) Location. The following area is a temporary safety zone...-AA00 Safety Zone; Sault Sainte Marie 4th of July Fireworks, St. Mary's River, Sault Sainte Marie, MI...

Nevi and lasers: Practical considerations.

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Rogers, Tova; Krakowski, Andrew C; Marino, Maria L; Rossi, Anthony; Anderson, Richard R; Marghoob, Ashfaq A

2018-01-01

Lasers are increasingly used for elective ablation of melanocytic nevi (MN). However, the associated risks of treating MN with lasers are debated and not well studied. Theoretical risks include inadvertently treating a melanoma mistaken for a nevus, the inability to remove all nevus cells and the possibility for residual cells to undergo malignant transformation, and the difficulty in clinically monitoring the remnant nevus for melanoma progression. Additional concerns include the morphological suitability of a lesion for laser removal and managing patients' expectations about the variable cosmetic outcomes. These potential issues have prompted us to outline some practical suggestions for clinicians and patients to consider when determining the suitability of a nevus for laser ablation. The choice to perform laser removal of a nevus is personal, both from the perspective of the treating physician and that of the person being treated. While acknowledging some uncertainty, we believe that these suggestions can help mitigate risk and improve patient outcomes. Lasers Surg. Med. 50:7-9, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

Topical application of dimethylbenz[a]anthracene results in the generation of multiple melanocytic nevi in C3H/HeN mice

International Nuclear Information System (INIS)

Elmets, Craig A.; Yusuf, Nabiha; Hamza, Sate; Iranikakh, Nasser; Smith, Jeffrey; Volk, Andrea L.; Skelton, Henry; Smith, Kathy

2004-01-01

Melanocytic nevi are a common dermatological problem for which there are few in vivo models. It has been postulated that environmental factors contribute to their development. Experiments were therefore conducted to determine whether application of dimethylbenz[a]anthracene (DMBA) to the skin of mice would result in the development of melanocytic nevi. One hundred microliters of a 0.1%, 0.5%, or 1.0% solution of DMBA was applied to the dorsal skin of C3H/HeN mice. The mice were then observed for the appearance of pigmented lesions. Histological examination revealed perifollicular accumulations of nevus cells, which were S-100-protein and HMB-45-positive, confirming their melanocytic origin. Pigmented lesions did not occur in animals treated with vehicle alone. Dose response studies revealed both greater numbers of nevi and lesions with larger diameters as the dose of DMBA was increased from 0.1% to 0.5%. In no instance was an invasive melanoma observed even after 40 weeks. The fact that melanocytic nevi can be produced by topical application of DMBA suggests that xenobiotics may play a previously unrecognized role in the development of this common benign neoplasm. Because this is one of the only animal models for melanocytic nevi, further examination of this model may facilitate identification of the molecular and biochemical mechanisms that lead to the development of pigmented nevi and the factors that promote their evolution into invasive melanomas

Appraisal of the PREP, KITT, and SAMPLE computer codes for the evaluation of the reliability characteristics of engineered systems

Energy Technology Data Exchange (ETDEWEB)

Shaw, P; White, R F

1976-01-01

For the probabilistic approach to reactor safety assessment by the use of event tree and fault tree techniques it is essential to be able to estimate the probabilities of failure of the various engineered safety features provided to mitigate the effects of postulated accident sequences. The PREP, KITT and SAMPLE computer codes, which incorporate Kinetic Tree Theory, perform these calculations and have been used extensively to evaluate the reliability characteristics of engineered safety features of American nuclear reactors. Working versions of these computer codes are now available in SRD, and this report explains the merits, capabilities and ease of application of the PREP, KITT, and SAMPLE programs for the solution of system reliability problems.

Sexual Harassment and Sexual Harassment Policy in Jamaica: The Absence of a National Sexual Harassment Policy, and the Way Forward

OpenAIRE

R. Peters; P.A. Bourne

2012-01-01

Within the Caribbean only countries such as Belize, Bahamas and Guyana have legitimized legislation against sexual harassment. Countries such as Jamaica, Barbados and St. Kitts and Nevis have draft bills before parliament. In the Jamaican context, the country in September 1981 signed the Convention on the Elimination of All Forms of Discrimination Against Women (CEDAW) which came into effect in 1984 which deals with the issue of sexual harassment under Articles 2 (Policy Measures and Legislat...

Small Dysplastic Congenital Melanocytic Nevi in Childhood as Possible Melanoma Imitators

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Georgi Tchernev

2018-01-01

Full Text Available Small pigmented lesions in children can represent a significant diagnostic challenge. If the diagnostic features and therapeutic approach are relatively well established in large and giant nevi, there is still much controversy regarding small and intermediate-sized congenital pigmented lesions that can lead to significant diagnostic challenges, both clinically and dermoscopically, and consequently to difficulty in defining the optimal approach in such cases. Although dermoscopy can be useful in the diagnosis of pigmented lesions, the diversity of clinical and dermoscopic features of pigmented nevi in children usually hinder the differentiation between them and melanoma. Histological findings after resection often show surprising results that do not correspond either to the clinical nor the dermoscopic features. With the present case, we want to emphasise the variable natural behaviour of melanocytic lesions in children, which sometimes leads to unnecessary surgical excisions, which should be avoided in pediatric patients.

[TREATMENT OBSERVATION OF NASAL TIP DEFECTS RECONSTRUCTED BY BILOBED FLAPS AFTER GAINT NEVI EXCISION].

Science.gov (United States)

Li, Zhengyong; Pu, Yi; Cen, Ying; Wu, Junliang; Zhang, Zhenyu

2016-11-08

To discuss a reliable and aesthetic surgery method for the reconstruction of large defects on the top of nose after giant nevi resection. Between January 2011 and June 2015, 46 cases of nasal tip defects caused by giant nevi resection were treated. Of 46 cases, 22 were male and 24 were female, aged 15-59 years (median, 28 years). The right ala nasi was involved in 28 cases, the apex nasi in 8 cases, and the left ala nasi in 10 cases. The diameters of nevi were from 8 to 12 mm (mean, 9.75 mm); no alar cartilage was invaded. Hair growth was seen in 14 cases. The duration of nasal nevi was from 3 years to 49 years (mean, 9.8 years). There were 9 recurrent patients who received laser therapy before surgery. The defects sizes after excision were from 10 mm×10 mm to 14 mm×14 mm. The bilobed flaps were used for one-stage reconstruction, which sizes were from 11 mm×10 mm to 15 mm×14 mm and from 10 mm×10 mm to 15 mm×14 mm. All the incisions healed by first intention, and the flaps survived. No complication of intracranial hemorrhage or subdural hemorrhage occurred. The patients were followed up 6 months to 5 years (mean, 18 months). The appearance of nasal tip and nasolabial fold was satisfactory, and no recurrence was found during follow-up. One-stage bilobed flap reconstruction for nasal tip defects after giant nevus resection is one of the effective, safe, and aesthetic surgery methods.

A novel strategy to protect Sutton’s nevi during forced or voluptuary exposition to sun rays

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Lorenzo Martini

2017-07-01

Full Text Available Albeit halo nevi are estimated to be present in approximately 1% of the general population, and they are found to be more prevalent in people with vitiligo, malignant melanoma or Ullrich-Turner’ s syndrome, it is not necessary evident that their presence in human body is to be associated to vitiligo and/or melanoma, both genetically and pathophisiologically. In this study I want to demonstrate how it can be safe to expose Sutton’s nevi (halo nevi to all the sun rays (even the most dangerous during all the daylight, employing two natural cosmetic items: the former based on natural juleps made of polychrome algae (and it is to be considered the absorber sun filter and the latter is a physical sun blocking agent, apt to reflect all the UV rays. The former must be spread onto the halo, the latter, after half an hour, onto the nevus itself.

Extrasolar Planet Transits Observed at Kitt Peak National Observatory

Science.gov (United States)

Sada, Pedro V.; Jennings, Donald E.; Deming, Drake; Jennings, Donald E.; Jackson, Brian; Hamilton, Catrina M.; Fraine, Jonathan; Peterson, Steven W.; Haase, Flynn; Bays, Kevin;

Survey report: Eastern Caribbean.

Science.gov (United States)

Yinger, N

1991-01-01

Over 1 million people live on 8 small islands in the Eastern Caribbean: St. Kitts-Nevis, Montserrat, Grenada, St. Vincent, Antigua, Barbados, St. Lucia, and Dominica. Starting in 1985 the International Planned Parenthood Federation, Western Hemisphere Region has carried out a series of contraceptive prevalence surveys in these countries. Current information is provided by these surveys in the areas of fertility levels and preferences, contraceptive knowledge and use. Also, socioeconomic, historical and demographic background and analysis such as fertility patterns, desire for additional children, and breastfeeding data; contraceptive awareness including family planning methods and sources; contraceptive use by method, source, and timing, satisfaction, and male attitudes are provided in the surveys, but not in the report abstracted here. The total fertility rate (TFR) and the contraceptive prevalence rate (CPR) for the 8 islands are as follows: St. Kitts-Nevis (1984) 2.9 TFR, 40.6 CPR; St. Vincent (1988) 2.9 TFR, 58.3 CPR; Antigua (1988) 1.8 TFR, 52.6 CPR; Barbados (1988) not given, 55.0 CPR; St. Lucia (1988) 3.2 TFR, 47.3 CPR; Dominica (1987) 3.2 TFR, 49.8 CPR. The islands have unusual demographic patterns related to extensive out-migration.

Making midwives: postmodern conditions and midwifery training in Saint Lucia.

Science.gov (United States)

Hsu, C

2001-01-01

Drawing on material from fieldwork conducted on the island of Saint Lucia, I examine how Saint Lucian nurse-midwives and student midwives negotiate multiple ways of understanding and evaluating their practices and roles in light of contradictory and powerful cultural, historical, and political forces. I argue that, although Saint Lucian nurse-midwives may not qualify as "postmodern" according to the criteria proposed by Davis-Floyd and Davis (1996), they are nonetheless struggling with postmodern conditions as they negotiate between competing healing ideologies. I illustrate the significance of these negotiations through analyzing: (1) the ways nurse-midwives understand and articulate the healing ideologies at play in Saint Lucia, (2) historical and ideological aspects of the Saint Lucian nurse-midwifery training program, and (3) a classroom discussion during which student reported on "bush-midwives."

Differing lectin-binding patterns of malignant melanoma and nevocellular and Spitz nevi.

Science.gov (United States)

Kohchiyama, A; Oka, D; Ueki, H

1987-01-01

The lectin-binding patterns of primary malignant melanoma, nevocellular nevus, and Spitz nevus were studied on formalin-fixed, paraffin-embedded sections using a series of biotinylated lectins--concanavalin A (ConA), Ricinus communis agglutinin-1 (RCA1), dolichos biflorus agglutinin (DBA), soybean agglutinin (SBA), maclura pomifera agglutinin (MPA), peanut agglutinin (PNA), wheat germ agglutinin (WGA), and Ulex europeus agglutinin-1(UEA1)--and employing the avidin-biotin-peroxidase complex method. In nevocellular and Spitz nevi, all of the nevus cells were positively stained with ConA and RCA1. No positive staining was observed, however, with the other lectins and no change in binding patterns occurred following neuraminidase pretreatment. In malignant melanoma, all of the melanoma cells were positively stained with ConA and RCA1, and some were also stained with MPA, PNA, and WGA. In addition, DBA, SBA, MPA, PNA, and WGA labeled all of the melanoma cells after neuraminidase pretreatment. No positive staining was observed with UEA1 despite neuraminidase pretreatment. The present results showed that malignant melanoma and nevocellular and Spitz nevi have different lectin-binding patterns and different responses to neuraminidase pretreatment. We, therefore, believe that the lectin staining on paraffin-embedded sections can be a useful probe for the differentiation of these diseases.

Saint: a lightweight integration environment for model annotation.

Science.gov (United States)

Lister, Allyson L; Pocock, Matthew; Taschuk, Morgan; Wipat, Anil

2009-11-15

Saint is a web application which provides a lightweight annotation integration environment for quantitative biological models. The system enables modellers to rapidly mark up models with biological information derived from a range of data sources. Saint is freely available for use on the web at http://www.cisban.ac.uk/saint. The web application is implemented in Google Web Toolkit and Tomcat, with all major browsers supported. The Java source code is freely available for download at http://saint-annotate.sourceforge.net. The Saint web server requires an installation of libSBML and has been tested on Linux (32-bit Ubuntu 8.10 and 9.04).

Gateway to the Syriac Saints: A Database Project

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Jeanne-Nicole Mellon Saint-Laurent

2016-04-01

Full Text Available This article describes The Gateway to the Syriac Saints, a database project developed by the Syriac Reference Portal (www.syriaca.org. It is a research tool for the study of Syriac saints and hagiographic texts. The Gateway to the Syriac Saints is a two-volume database: 1 Qadishe and 2 Bibliotheca Hagiographica Syriaca Electronica (BHSE. Hagiography, the lives of the saints, is a multiform genre. It contains elements of myth, history, biblical exegesis, romance, and theology. The production of saints’ lives blossomed in late antiquity alongside the growth of the cult of the saints. Scholars have attended to hagiographic traditions in Greek and Latin, but many scholars have yet to discover the richness of Syriac hagiographic literature: the stories, homilies, and hymns on the saints that Christians of the Middle East told and preserved. It is our hope that our database will give scholars and students increased access to these traditions to generate new scholarship. The first volume, Qadishe or “saints” in Syriac, is a digital catalogue of saints or holy persons venerated in the Syriac tradition. Some saints are native to the Syriac-speaking milieu, whereas others come from other linguistic or cultural traditions. Through the translation of their hagiographies and the diffusion of saints’ cults in the late antique world, saints were adopted, “imported,” and appropriated into Syriac religious memory. The second volume, the BHSE, focuses on Syriac hagiographic texts. The BHSE contains the titles of over 1000 Syriac stories, hymns, and homilies on saints. It also includes authors’ or hagiographers’ names, the first and last lines of the texts (in Syriac, English, and French, bibliographic information, and the names of the manuscripts containing these hagiographic works. We have also listed modern and ancient translations of these works. All of the data in the Gateway to the Syriac Saints has been encoded in TEI, and it is fully

Identification of feline immunodeficiency virus subtype-B on St. Kitts, West Indies by quantitative PCR.

Science.gov (United States)

Kelly, Patrick J; Stocking, Ruey; Gao, Dongya; Phillips, Nikol; Xu, Chuanling; Kaltenboeck, Bernhard; Wang, Chengming

2011-07-04

Although antibodies to the feline immunodeficiency virus (FIV) have been detected by SNAP assay in cats from St. Kitts, there have been no molecular studies to further confirm the infection and determine the FIV subtypes present. Total nucleic acids were extracted from EDTA whole blood specimens from 35 cats, followed by quantitative fluorescence resonance energy transfer (FRET) PCR under a six-channel LightCycler 2.0 Instrument with Software version 4.1. Four of 11 stray cats (36 %) but none of 24 owned cats were FIV positive by real-time PCR.  High-resolution melting curve analysis indicated that all four positive cats were infected with FIV subtype-B. This is the first molecular characterization of FIV subtypes on St. Kitts and the results confirm the high prevalence of FIV infection in stray cats on the island.

Prevalence of ciguatoxins in lionfish (Pterois spp.) from Guadeloupe, Saint Martin, and Saint Barthélmy Islands (Caribbean).

Science.gov (United States)

Soliño, Lucía; Widgy, Saha; Pautonnier, Anthony; Turquet, Jean; Loeffler, Christopher R; Flores Quintana, Harold A; Diogène, Jorge

2015-08-01

Lionfish (Pterois spp.) are invasive species that have recently spread throughout the Caribbean. Lionfish are available for purchase in local markets for human consumption in several islands of the region. We examined the prevalence of ciguatoxins (CTXs) in lionfish from the French Antilles, a ciguatera-endemic region. The neuroblastoma-2a (N2a) cell assay was used to assess composite cytotoxicity in 120 fish samples collected from the surrounding waters of Guadeloupe (n = 60), Saint Barthélemy Islands (n = 55) and Saint Martin (n = 5). Twenty-seven of these samples exhibited CTX-like activity by the N2a assay. Ciguatoxin (CTX) was confirmed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in multiple samples that presented highest composite toxicity levels by N2a. Those fish found to contain CTXs were all from Saint Barthélemy. Lionfish from Guadeloupe and Saint Martin did not exhibit toxin activity, although the sample size from Saint Martin was insufficient to draw any conclusions as to the incidence of CTXs. In this study, we provide information about the potential hazard of ciguatera associated with the consumption of lionfish from known endemic areas. We also demonstrate the utility of the cell-based assay combined with LC-MS/MS to assess activity and to provide structural confirmation of CTXs respectively. Copyright © 2015 Elsevier Ltd. All rights reserved.

The sacred disease and its patron saint.

Science.gov (United States)

Fatović-Ferencić, S; Dürrigl, M A

2001-08-01

Although the Hippocratic natural theory of epilepsy as a brain disorder originated around 400 bc , it did not begin to take root until the 18th and 19th centuries, leaving the intervening centuries dominated by mostly supernatural concepts. This article provides historical insight into human behavior when afflicted with disease: supplication to a patron saint, Saint Valentine, a cult that spread throughout Europe.

The features of Saint Louis

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Pierre-Yves Le Pogam

2017-12-01

Full Text Available The recent ninth centenary of the birth of Saint Louis, in 2014, gave the possibility to renew the study of the man and his reign, so important for French history, not in a nationalistic agenda or for a mere celebration, but in order to shed new light on a figure indeed profoundly studied but deserving a repeated attention, so much Louis IX lends to many-sided, even contradictory explanations. In the past, one has paid an almost maniacal attention to the point of the physical appearance of the king, looking in some images for a reflection of, or indeed a portrait of Saint Louis. Or, on the contrary and more recently, one has denied any validity to this trend of studies. In line with the essay I devoted on this question in the catalogue of the recent exhibition on Saint Louis in Paris, I would like here to go further in the analysis, especially regarding the meaning of details of the dress and bodily features of the saint king.

Melanocytic nevi and non-neoplastic hyperpigmentations.

Science.gov (United States)

Clemente, C

2017-06-01

This is the first of three chapters that will be progressively published on Pathologica as updating activity of the Italian Study Group of Dermatopathology (GISD), Italian Society of Pathology and Cytology (SIAPeC IAP). The first chapter concerns non-neoplastic hyperpigmented skin lesions and nevi, the second will address the topics of dysplastic nevus, borderline and low malignant potential melanocytic proliferations and the third melanoma in its variants and differential diagnoses with a supplement on the immunohistochemistry and molecular support to diagnostic and prognostic definition of nevi and melanomas. Although we believe that great advances were made in the application of ancillary genetic, immunohistochemical and molecular techniques, for the diagnosis and biological characterization of melanocytic tumors the morphology still remains the gold standard. These chapters are not intended as substitutes or even claim to be compared to the numerous and valuable texts that are also recently published, but they want to present, concisely and quickly available, all of those traits that we believe essential to the histopathological evaluation of a melanocytic lesion. No morphological parameter is exclusive and individually sufficient to make the correct diagnosis of nevus or melanoma but to reach a final conclusive and appropriate interpretation a set of morphological characters must be evaluated and compared. I was lucky enough to be able to examine several thousand cases and to draw lessons from each of these increasing my diagnostic experience. I had a great lesson by my teacher and good friend Prof. Martin C. Mihm Jr of Boston, dermato-pathologist with undisputed international reputation, who, with great passion, patience and friendship, transferred me much of his experience and knowledge and for which I always thank him. Special thanks I would like to address Dr. Agostino Crupi, dermatologist, skin-oncologist and brilliant dermatoscopist who taught me how the

Premalignant quiescent melanocytic nevi do not express the MHC class I chain-related protein A

Directory of Open Access Journals (Sweden)

Mercedes B. Fuertes

2011-08-01

Full Text Available The MHC class I chain-related protein A (MICA is an inducible molecule almost not expressed by normal cells but strongly up-regulated in tumor cells. MICA-expressing cells are recognized by natural killer (NK cells, CD8+ aßTCR and ?dTCR T lymphocytes through the NKG2D receptor. Engagement of NKG2D by MICA triggers IFN-? secretion and cytotoxicity against malignant cells. Although most solid tumors express MICA and this molecule is a target during immune surveillance against tumors, it has been observed that high grade tumors from different histotypes express low amounts of cell surface MICA due to a metalloprotease- induced shedding. Also, melanomas develop after a complex process of neotransformation of normal melanocytes. However, the expression of MICA in premalignant stages (primary human quiescent melanocytic nevi remains unknown. Here, we assessed expression of MICA by flow cytometry using cell suspensions from 15 primary nevi isolated from 11 patients. When collected material was abundant, cell lysates were prepared and MICA expression was also analyzed by Western blot. We observed that MICA was undetectable in the 15 primary nevi (intradermic, junction, mixed, lentigo and congenital samples as well as in normal skin, benign lesions (seborrheic keratosis, premalignant lesions (actinic keratosis and benign basocellular cancer. Conversely, a primary recently diagnosed melanoma showed intense cell surface MICA. We conclude that the onset of MICA expression is a tightly regulated process that occurs after melanocytes trespass the stage of malignant transformation. Thus, analysis of MICA expression in tissue sections of skin samples may constitute a useful marker to differentiate between benign and malignant nevi.

Clinical and histological responses of congenital melanocytic nevi after single treatment with Q-switched lasers

NARCIS (Netherlands)

Grevelink, JM; vanLeeuwen, RL; Anderson, RR; Byers, HR

Background: Laser irradiation of congenital melanocytic nevi is a controversial treatment. Recurrence of lesions after laser treatment appears to be the rule, and the effects of laser irradiation on cellular biological behavior and the possible mutagenic responses of nevomelanocytes that have

The church Saint-Symphorien in Nuits-Saint-Georges. An architectural and decorative syncretism, ca 1220-1240

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Sylvain Demarthe

2011-12-01

Full Text Available Saint Symphorian’s church in Nuits-Saint-Georges (Burgundy, which dates from near 1220-1240, is situated during the transition of two architectural styles and attests a local but rather backward-looking Cistercian legacy that some Gothic urban and more innovative elements modernize. Moreover the church takes part, for the same reasons as those in Agencourt, Gerland and Prissey, in the surprising wave of reconstructions which denotes among others the important economic development of the country of Cîteaux at the beginning of the 13th century.

Who is Jesus Christ for the Ruthenian and Russian Saints? A Theological Exploration of St Dimitry Rostovsky’s The Lives of the Saints

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Krzysztof Leśniewski

2014-12-01

Full Text Available Christian hagiography reveals not only the facts of life of individual saints, but first of all, it is a description of theexperience of God loving mankind. From the beginning of Christianity, of great importance in building faith, hope andlove had had stories about those believers who responded with a particular radicalism for the prevenient love of God inthe Trinity of Persons. These stories have been written in various forms of literature.Author in the introductory part of the article introduces into the lives of the saints and their role in the Ruthenian andRussian Orthodoxy. Essentially he focuses on presenting The Menaia edited by St Dimitry Rostovski. This book waspublished in the years 1711 to 1718 in Old Church Slavonic. At the beginning of the twentieth century, it has been rewrittenand translated into Russian. This monumental work appeared in the years 1903-1911 under the title The Lives of theSaints. It has been a rich source of information for researchers from many disciplines.From a theological point of view, the author studied The Lives of the Saints in order to find direct references to theperson and teaching of Jesus Christ. For this purpose, he analyzed quotations from the New Testament, especially fromthe Gospel, referring directly to the Person and teaching of Jesus Christ, as well as the prayers addressed to Him. In hisanalysis, he searched for answers to the questions: Who is Jesus Christ for the Ruthenian and Russian saints, and whatkind of His images predominate in The Lives of the Saints.The first part of the article, on the basis of source texts, indicates personal qualities of Jesus Christ. The Savior hasbeen experienced by the Ruthenian and Russian saints as God who is close to man, the blessed King, the best Lord, theComforter of the crying, the Light, the merciful God, and the Foundation of all good. The image of Christ as sinless,innocent suffering and merciful shines especially in the devotion of Saints Passion

A "Sacra Rappresentazione" of Saint Apollonia's Martyrdom.

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Eramo, Stefano; Natali, Alessio; Bravi, Monia; Cella, Diana; Milia, Egle

The literary sources of Saint Apollonia's martyrdom and the evolution of Medieval and Renaissance religious drama are presented along with the compendium of a "Sacra Rappresentazione" from Italian Renaissance regarding Saint Apollonia's Martyrdom. Copyright American Academy of the History of Dentistry.

Saint rulers as a category of sanctity in Orthodoxy

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Jarosław Charkiewicz

2015-11-01

Full Text Available In the wide spectre of Orthodox human sanctity, among others, there is also a category of saint rulers. Despite the fact that it’s represented by a significant number of saints, it remains, utterly undeservedly, in the shadow of the others – more known or more deeply rooted historically. On top of that, the situation may result as well from the fact that saint rulers, as a distinct category of saint, are not separately mentioned neither during the proskomedia, nor during the intercessory prayer of the anaphora. Still, the saint rulers definitely should be considered a separate type of sanctity, deserving a somehow wider presentation. Such is therefore the aim of this article.It is also an attempt of suggesting an interior systematic of this category of sanctity. Preserving, appearing in science, classifications of the saint rulers, the author gives also his own proposition. In the category of saint rulers there are four following groups: (1 rulerswho weren’t neither martyrs nor monks or passion-bearers, (2 rulers who died martyrs, (3 rulers who long before their death became monks and led monastic life, (4 rulers-passion-bearers.

Lack of GNAQ and GNA11 germ-line mutations in familial melanoma pedigrees with uveal melanoma or blue nevi

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Jason Ezra Hawkes

2013-06-01

Full Text Available Approximately 10% of melanoma cases are familial, but only 25-40% of familial melanoma cases can be attributed to germ-line mutations in the CDKN2A - the most significant high-risk melanoma susceptibility locus identified to date. The pathogenic mutation(s in most of the remaining familial melanoma pedigrees have not yet been identified. The most common mutations in nevi and sporadic melanoma are found in BRAF and NRAS, both of which result in constitutive activation of the MAPK pathway. However, these mutations are not found in uveal melanomas or the intradermal melanocytic proliferations known as blue nevi. Rather, multiple studies report a strong association between these lesions and somatic mutations in Guanine nucleotide-binding protein G(q subunit alpha (GNAQ, Guanine nucleotide-binding protein G(q subunit alpha-11 (GNA11 and BRCA1 associated protein-1 (BAP1. Recently, germ-line mutations in BAP1, the gene encoding a tumor suppressing deubiquitinating enzyme, have been associated with predisposition to a variety of cancers including uveal melanoma, but no studies have examined the association of germ-line mutations in GNAQ and GNA11 with uveal melanoma and blue nevi. We have now done so by sequencing exon 5 of both of these genes in 13 unique familial melanoma pedigrees, members of which have had either uveal or cutaneous melanoma and/or blue nevi. Germ-line DNA from a total of 22 individuals was used for sequencing; however no deleterious mutations were detected. Nevertheless, such candidate gene studies and the discovery of novel germ-line mutations associated with an increased MM susceptibility can lead to a better understanding of the pathways involved in melanocyte transformation, formulation of risk assessment, and the development of specific drug therapies.

UNDER THE PROTECTION OF THE GOD'S SAINT. DYKANKA IMAGE OF SAINT NICHOLAS THE WONDER-WORKER AND ITS ROLE IN NIKOLAI GOGOL'S LIFE

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Voropaev V. A.

2008-11-01

Full Text Available The article tells the history of St. Nicholas Church in Dykanka and its holy image of Saint Nicholas, examines some details of the Gogol family life, the legend of Maria Gogol-Yanovskaya's marriage and her oath in front of the Holy Saint icon.

Migration and rural development in the Caribbean.

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Momsen, J D

1986-01-01

The relationship between migration and agricultural development in the Caribbean is examined. The data, collected by survey, concern the islands of Nevis, Montserrat, and Saint Lucia. The results show that migration is not associated with agricultural innovation or the use of specific technical inputs and that it frequently has a negative impact on agricultural productivity and attitudes toward farming.

Expression of Bcl-2, Melan A and HMB-45 in Dysplastic Nevi.

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Patrascu, Oana Maria; Costache, Mariana; Dumitru, Adrian Vasile; Mehotin, Corina Nicoleta; Sajin, Maria; Lazaroiu, Anca Mihaela

2016-03-01

From the first recognition of dysplastic nevi as a pathology per se, many debates have been raised and many histological and immunohistological studies have been conducted in order to establish the true significance of these lesions. Therefore, the aim of this study was to establish if there is a correlation between HMB-45, Melan A and Bcl-2 expression and the grade of dysplasia, as well as between the marker's staining patterns. Ten dysplastic nevi from six female patients were selected and their histological features (size, dysplasia), as well as the immunohistological staining patterns, were studied (HMB-45, Melan A, Bcl-2). The Pearson correlation coefficient and regression was calculated with Windows Excel Data Analysis. We demonstrated that there was a notable correlation between the dysplasia and the size of the lesions (r(8)= 0.62 with p-value= 0.052), and also between Melan A and Bcl-2 (a r(6)= 0.73, p0.05). We can affirm, at least in our cases, there is a correlation between the grade of dysplasia and the size of the lesion, and also, that there is a correlation between Melan A and Bcl-2 staining, explained by MITF gene. These results were only partial concordant with those in other studies, therefore a larger number of cases is recommended to be further analyzed in order to clearly draw a conclusion.

Abundance of the benign melanocytic universe: Dermoscopic-histopathological correlation in nevi.

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Woltsche, Nora; Schmid-Zalaudek, Karin; Deinlein, Teresa; Rammel, Katrin; Hofmann-Wellenhof, Rainer; Zalaudek, Iris

2017-05-01

The broad universe of "melanocytic nevi" includes a variety of different subtypes, which can be classified either due to their morphology, epidemiology, genetic alterations or risk for developing melanoma. Regarding morphology, on the one hand macroscopic/clinical and on the other hand histopathological appearance were used to subdivide in the past, often resulting in confusion and poor interobserver agreement, while nowadays dermoscopy presents the clinician's precious bridge between naked-eye examination and histopathological diagnostics, allowing prediction of the lesions' histopathology, follow up and monitoring over time without need of excision. The non-invasive dermoscopic examination relies on the assessment of colors, patterns and the distribution of both within a cutaneous lesion. Until today, the correspondence of certain dermoscopic colors and patterns to certain histopathological correlates has been reported for a huge amount of different cutaneous lesions. Moreover, the correspondence of certain dermoscopic features to certain body sites, age groups and pigmentary traits, but also to specific genetic alterations in lesions, has been broadly investigated. Dermoscopy has led us to a new understanding of melanocytic nevi's biology and evolution and, last but not least, to a new classification system, which we want to present herein. © 2017 Japanese Dermatological Association.

Towards robust identification and tracking of nevi in sparse photographic time series

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Vogel, Jakob; Duliu, Alexandru; Oyamada, Yuji; Gardiazabal, Jose; Lasser, Tobias; Ziai, Mahzad; Hein, Rüdiger; Navab, Nassir

2014-03-01

In dermatology, photographic imagery is acquired in large volumes in order to monitor the progress of diseases, especially melanocytic skin cancers. For this purpose, overview (macro) images are taken of the region of interest and used as a reference map to re-localize highly magni ed images of individual lesions. The latter are then used for diagnosis. These pictures are acquired at irregular intervals under only partially constrained circumstances, where patient positions as well as camera positions are not reliable. In the presence of a large number of nevi, correct identi cation of the same nevus in a series of such images is thus a time consuming task with ample chances for error. This paper introduces a method for largely automatic and simultaneous identi cation of nevi in di erent images, thus allowing the tracking of a single nevus over time, as well as pattern evaluation. The method uses a rotation-invariant feature descriptor that uses the local neighborhood of a nevus to describe it. The texture, size and shape of the nevus are not used to describe it, as these can change over time, especially in the case of a malignancy. We then use the Random Walks framework to compute the correspondences based on the probabilities derived from comparing the feature vectors. Evaluation is performed on synthetic and patient data at the university clinic.

REPRESENTATION OF THE SAINTS IN ORTHODOX ICONOGRAPHY

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Veronica GHEORGHIȚĂ

2014-06-01

Full Text Available In Romanian iconography, the icon is described as an image of truth, expressing, strengthening and teaching the truth of orthodox faith. Adept and guardian of the byzantine style, the icon depicts the saints in their divine and human nature, but has traits that show the holiness, perfection and simplicity of their life. Given that the saints have been seen as modest, abstinent, fasting people, they have never been portrayed as overweight, but thin, with hollow cheeks and a frail physical appearance. In fact, the iconographic representations are characterized by a high ability to summarize the reality, the physical appearance of the saints being non-anatomical, disproportionate. Lately, it has been noticed in certain iconographic representations a change in painting style: to reproduce reality as faithfully as possible. The orientation toward the icon's external beauty involved the redefinition of the iconic portrait of the saints, who are depicted as human as possible.

Saint rulers as a category of sanctity in Orthodoxy

OpenAIRE

Jarosław Charkiewicz

2015-01-01

In the wide spectre of Orthodox human sanctity, among others, there is also a category of saint rulers. Despite the fact that it’s represented by a significant number of saints, it remains, utterly undeservedly, in the shadow of the others – more known or more deeply rooted historically. On top of that, the situation may result as well from the fact that saint rulers, as a distinct category of saint, are not separately mentioned neither during the proskomedia, nor during the intercessory pray...

Clinical Characteristics of Connective Tissue Nevi in Tuberous Sclerosis Complex With Special Emphasis on Shagreen Patches.

Science.gov (United States)

Bongiorno, Michelle A; Nathan, Neera; Oyerinde, Oyetewa; Wang, Ji-An; Lee, Chyi-Chia Richard; Brown, G Thomas; Moss, Joel; Darling, Thomas N

2017-07-01

Patients with tuberous sclerosis complex (TSC) frequently develop collagenous connective tissue nevi. The prototypical lesion is a large shagreen patch located on the lower back, but some patients only manifest small collagenomas or have lesions elsewhere on the body. The ability to recognize these variable presentations can be important for the diagnosis of TSC. To describe the clinical characteristics of connective tissue nevi on the trunk and extremities of patients with tuberous sclerosis complex. A retrospective analysis of patient medical records and skin photography was performed; 104 adult patients with TSC were enrolled in an observational cohort study that was enriched for those with pulmonary lymphangioleiomyomatosis, and was therefore composed mostly of women (99 women, 5 men). All patients included were examined at the National Institutes of Health (NIH) in Bethesda, Maryland, from 1998 to 2013. Connective tissue nevi were categorized per anatomic location and size. Lesions less than 1 cm in diameter were termed collagenomas. Shagreen patches were characterized as small (1 to connective tissue nevi in patients with TSC. Overall, 58 of 104 patients (median [range] age, 42 [19-70] years) with TSC (56%) had at least 1 connective tissue nevus on the trunk or thighs; of these, 28 of 58 patients (48%) had a solitary lesion, and 30 of 58 patients (52%) had 2 or more lesions. Overall, 120 lesions from 55 patients were classified by size; 46 lesions (38%) were collagenomas; 39 lesions (32%) were small shagreen patches; 21 lesions (18%), medium shagreen patches; and 14 lesions (12%), large shagreen patches. The distribution of lesions was 9% (n = 11), upper back; 29% (n = 35), middle back; 51% (n = 61), lower back; and 11% (n = 13), other locations. All 26 shagreen patches that were analyzed histopathologically had coarse collagen fibers and 24 of 26 stained with Miller elastic stain had decreased elastic fibers. On immunoblot analysis

René Goupil: patron saint of anesthetists.

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Quintal, J

1995-06-01

René Goupil, the patron saint of anesthetists, is addressed mainly as a 17th century French surgeon who practiced his art in North America. He is also presented as a Jesuit martyr and saint. The article freely borrows from past writings of Jesuits on René Goupil.

Where’s Cap Haitien? Validating the Principles of Peace Operations

Science.gov (United States)

1999-12-17

health risks to the military with exposure to disease, specifically malaria and dengue fever. Former members of the FAD’H posed potential security...Co (TACON) C/65 EN (L) (DS) (-) 3/58 MP CO (DS) 1/A/125SIGBN(+) DPSE 22 TPT 221 TPT 223 CATPT-2/416CABN SEC/351 AG CO (POSTAL) (DS) (-) MIST...Barbuda, the Bahamas, Barbados, Belize , Dominica, Grenada, Guyana, Jamaica, St. Kitts and Nevis, St. Lucia, St Vincent and the Grenadines, and Trinidad

Oral findings in a patient with Sebaceous Nevi - A Case Report.

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Baliga, Vidya; Gopinath, V P K; Baliga, Sudhindra; Chandra, Umesh

2013-10-01

The presentation herewith as scripted is to describe a case with Nevus sebaceous with oral manifestations. Nevus Sebaceous or Jadassohn's nevus is an epidermal nevus with predominant sebaceous glands seen histologically. Reports of oral involvement have been few ranging from papillomatous growths of the tongue, gingiva, palate to dental abnormalities such as anodontia and dysodontia. The present case describes a nevus sebaceous present on the right half of the face and neck, showing intraoral papillomatous growth on the lateral part of the tongue on the right side. The patient was healthy and did not report involvement of any other organ systems. Intraoral involvement may be seen in patients with Nevus Sebaceous, hence proper screening is important. In patients presenting with large nevi on the head and neck such as ours, involvement of other systems such as ocular, neurologic and oral lesions may be seen, therefore screening of such patients is of importance. Patients with nevus sebaceous may be predisposed to the occurrence of tumours. Therefore, careful screening of such patients is necessary. How to cite this article: Baliga V, Gopinath VP, Baliga S, Chandra U. Oral findings in a patient with Sebaceous Nevi - A Case Report. J Int Oral Health 2013; 5(5):139-42.

Earthquake Magnitude Relationships for the Saint Peter and Saint Paul Archipelago, Equatorial Atlantic

Science.gov (United States)

de Melo, Guilherme W. S.; do Nascimento, Aderson F.

2018-03-01

We have investigated several relationships between ML, M(NEIC) and Mw for the earthquakes locally recorded in the Saint Peter and Saint Paul Archipelago (SPSPA), Equatorial Atlantic. Because we only have one station in the area, we could not derive attenuation relations for events recorded at different distances at different stations. Our approach was then to compare our ML estimates with magnitudes reported by NEIC. This approach produced acceptable results particularly for epicentral distance smaller than 100 km. For distances greater that 100 km, there is a systematic increase in the residuals probable due to the lack of station correction and our inability to accurately estimate Q. We also investigate the Mw—M(NEIC) relationship. We find that Mw estimates using S-wave produce smaller residuals when compared with both M(NEIC). Finally, we also investigate the ML—Mw relationship and observe that given the data set we have, the 1:1 holds. We believe that the use of the present methodologies provide consistent magnitude estimates between all the magnitudes investigated that could be used to better assess seismic hazard in the region.

Saint Benedict of Palermo in Spain

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Bernard VINCENT

2016-06-01

Full Text Available Among the devotions to the black Saints, the one of which Benedict of Palermo was the object in Spain in the 17th and 18th centuries was the most remarkable. Born near Palermo to African slaves, this lay brother of a Sicilian franciscan convent, died in the odor of sanctity in 1589. His immediate popularity, encouraged both by the Church and by the Hispanic monarchy, was considerable within the communities of slaves and free blacks. Benedict was beatified in 1743, event which was followed by numerous celebrations and his eventual canonization in 1807. The fervour which surrounded him fade gradually because of the competition represented by the devotion to other black saints and by the very visible decline of slavery. However, thanks to the efforts of the franciscan order, the worship of Saint Benoît of Palermo continued until our days, particularly in Galicia.

Molecular Detection of Leptospiral DNA in Environmental Water on St. Kitts

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Julienne Rawlins

2014-08-01

Full Text Available Leptospirosis is an important waterborne zoonotic disease caused by pathogenic Leptospira. The pathogen is maintained in a population due to chronic colonization and shedding from renal tubules of domestic and wild animals. Humans and other animals become infected when they come in contact with urine from infected animals, either directly or through urine-contaminated surface water. In this study, we screened environmental water on the island of St. Kitts by using a TaqMan based real time quantitative polymerase chain reaction (qPCR targeting a pathogen specific leptospiral gene, lipl32. Our results indicate that around one-fifth of tested water sources have detectable leptospiral DNA.

ALICE takes root in Saint-Genis-Pouilly

CERN Multimedia

Patrice Loiez

2004-01-01

To celebrate the CERN 50th anniversary and to emphasize the close ties between the community of Saint-Genis-Pouilly, CERN and the ALICE Collaboration, Hubert Bertrand, Mayor of Saint-Genis-Pouilly and Christian Fabjan, Technical Coordinator of the ALICE Experiment, planted a tree on Saturday 16 October 2004 in front of the Jean Monet Culture Center.

ALICE takes root in Saint-Genis-Pouilly

CERN Multimedia

2004-01-01

To celebrate the CERN 50th anniversary and to emphasize the close ties between the community of Saint-Genis-Pouilly, CERN and the ALICE Collaboration, Hubert Bertrand, Mayor of Saint-Genis-Pouilly and Christian Fabjan, Technical Coordinator of the ALICE Experiment, planted a tree on Saturday 16 October 2004 in front of the Jean Monet Culture Center.

Locality and Distance in Cults of Saints in Medieval Norway

DEFF Research Database (Denmark)

Petersen, Nils Holger

2017-01-01

A discussion of the Norwegian medieval cult of the purported Irish St Sunniva, a cult in which holiness is seen as foreign and distant in the cultural memory of the saint.......A discussion of the Norwegian medieval cult of the purported Irish St Sunniva, a cult in which holiness is seen as foreign and distant in the cultural memory of the saint....

An Endogenous Electron Spin Resonance (ESR signal discriminates nevi from melanomas in human specimens: a step forward in its diagnostic application.

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Eleonora Cesareo

Full Text Available Given the specific melanin-associated paramagnetic features, the Electron Spin Resonance (ESR, called also Electron Paramagnetic Resonance, EPR analysis has been proposed as a potential tool for non-invasive melanoma diagnosis. However, studies comparing human melanoma tissues to the most appropriate physiological counterpart (nevi have not been performed, and ESR direct correlation with melanoma clinical features has never been investigated. ESR spectrum was obtained from melanoma and non-melanoma cell-cultures as well as mouse melanoma and non-melanoma tissues and an endogenous ESR signal (g = 2.005 was found in human melanoma cells and in primary melanoma tissues explanted from mice, while it was always absent in non-melanoma samples. These characteristics of the measured ESR signal strongly suggested its connection with melanin. Quantitative analyses were then performed on paraffin-embedded human melanoma and nevus sections, and validated on an independent larger validation set, for a total of 112 sections (52 melanomas, 60 nevi. The ESR signal was significantly higher in melanomas (p = 0.0002 and was significantly different between "Low Breslow's and "High Breslow's" depth melanomas (p<0.0001. A direct correlation between ESR signal and Breslow's depth, expressed in millimetres, was found (R = 0.57; p<0.0001. The eu/pheomelanin ratio was found to be significantly different in melanomas "Low Breslow's" vs melanomas "High Breslow's" depth and in nevi vs melanomas "High Breslow's depth". Finally, ROC analysis using ESR data discriminated melanomas sections from nevi sections with up to 90% accuracy and p<0.0002. In the present study we report for the first time that ESR signal in human paraffin-embedded nevi is significantly lower than signal in human melanomas suggesting that spectrum variations may be related to qualitative melanin differences specifically occurring in melanoma cells. We therefore conclude that this ESR signal

Of volcanoes, saints, trash, and frogs

DEFF Research Database (Denmark)

Andersen, Astrid Oberborbeck

, at the same time as political elections and economic hardship. During one year of ethnographic fieldwork volcanoes, saints, trash and frogs were among the nonhuman entities referred to in conversations and engaged with when responding to the changes that trouble the world and everyday life of Arequipans...

Screening of "Particule Fever" at Saint-Genis

CERN Multimedia

Brice, Maximilien

2015-01-01

La Mission Permanente de la France auprès des Nations Unies organise une projection gratuite du film "Particle Fever" jeudi 19 février 2015 à 19h30 au théâtre du Bordeau de Saint-Genis-Pouilly. Ce partenariat avec le CERN et la Ville de Saint-Genis-Pouilly permet de comprendre, au travers de ce film captivant, l'activité du CERN.

A comparative study of pulsed 532-nm potassium titanyl phosphate laser and electrocoagulation in the treatment of spider nevi.

NARCIS (Netherlands)

Erceg, A.; Greebe, R.J.; Bovenschen, H.J.; Seijger, M.M.B.

2010-01-01

OBJECTIVE: To assess the clinical efficacy and safety of potassium titanyl phosphate (KTP) laser treatment and electrocoagulation (EC) for the treatment of spider nevi (SN). METHOD: A randomized single-blind intrapatient comparison study was performed. A blinded observer and patients reported the

The pattern of distribution of laminin in neurogenic tumors, granular cell tumors, and nevi of the oral mucosa

DEFF Research Database (Denmark)

Reibel, J; Wewer, U; Albrechtsen, R

1985-01-01

. Accentuated staining was seen in Verocay bodies. In granular cell myoblastomas (GCM), small groups of tumor cells were encircled by laminin-positive material, whereas individual tumor cells were unstained. In nevi, diffusely spread nevus cells were surrounded by a rim of laminin, whereas when arranged...

Whorled hairless nevus of the scalp, linear hyperpigmentation, and telangiectatic nevi of the lower limbs: a novel variant of the "phacomatosis complex".

Science.gov (United States)

Castori, Marco; Scarciolla, Oronzo; Morlino, Silvia; Manente, Liborio; Biscaglia, Assunta; Fragasso, Alberto; Grammatico, Paola

2012-02-01

The term "phacomatosis" refers to a growing number of sporadic genetic skin disorders characterized by the combination of two or more different nevi and possibly resulting from non-allelic twin spotting. While phacomatosis pigmentovascularis (PPV) and pigmentokeratotica represent the most common patterns, some patients do not fit with either condition and are temporarily classified as unique phenotypes. We report on an 8-year-old boy with striking right hemihypoplasia, resulting in limb asymmetry and fixed dislocation of right hip. Skin on the affected side showed three distinct nevi: (i) A whorled, hairless nevus of the scalp in close proximity with (ii) epidermal hyperpigmentation following lines of Blaschko on the neck and right upper limb, and (iii) multiple telangiectatic nevi of the right lower limb and hemiscrotum. Didymosis atricho-melanotica was proposed for the combination of adjacent patchy congenital alopecia and linear hyperpigmentation, while phacomatosis atricho-pigmento-vascularis appears to define the entire cutaneous phenotype, thus implying the involvement of three neighboring loci influencing the development of distinct constituents of the skin. Given the striking asymmetry of the observed phenotype, the effect of mosaicism (either genomic or functional) for a mutation in a single gene with pleiotropic action and influenced by the lateralization pattern of early development cannot be excluded. Copyright © 2012 Wiley Periodicals, Inc.

The history of the missal directions of the All Saints Solemnity

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Jan Szczych

2009-09-01

Full Text Available The cult of the saints had its beginning in the Christian ancient times. Since then it was transformed in its own celebrations in honour of All the Saints. The official liturgy of the feast-day of Omnium Sanctorum (All Saints was stabilized in close relation to the development of collective worship of the saints in the West.  The historical liturgical witnesses from the Middle Ages and of the Trident Council time demonstrate a progressive and very natural process of establishment the missal texts of this liturgical celebration. The form of some liturgical directions in the current Missale Romanum (Latin Missal, unchanged for ages, confirms the continuity and constancy of this celebration in the history of Catholic Church. These missal directions explicitly show the same idea of celebration and timeless meaning of the All Saints Solemnity.

La collégiale Saint-Étienne de Neuvy-Saint-Sépulchre (Indre The collegiate church of Saint-Étienne at Neuvy-Saint-Sépulchre (Indre, France. A recent building survey of the rotunda and the nave

Directory of Open Access Journals (Sweden)

Simon Bryant

2006-05-01

Full Text Available La collégiale Saint-Étienne à Neuvy-Saint-Sépulchre (Indre est un des rares édifices subsistants en France qui soit conçu comme une copie de l’église du Saint-Sépulcre de Jérusalem. L’étude archéologique, réalisée pendant des travaux, a permis de préciser les étapes de son évolution depuis sa fondation dans les années 1040. La rotonde, avec ses onze piliers centraux, a été ajoutée à l’extrémité ouest d’une église antérieure. Le mur extérieur a été achevé dans cette première phase mais la cage centrale, qui abritait l’édicule, n’a été terminée qu’au début du XIIe s. Pendant la deuxième moitié du XIIe s., l’église est profondément remaniée et sans doute raccourcie avec la création d’un chevet plat. La voûte primitive est remplacée par trois travées de croisées d’ogives. L’édifice sert de refuge pendant la guerre de Cent Ans, ce qui provoque certains dégâts, partiellement réparés. Malgré les ruptures évidentes dans la construction et un plan irrégulier, l’étude montre que l’édifice est le résultat de la poursuite d’un projet architectural cohérent et original visant à évoquer l’église du Saint-Sépulcre de Jérusalem.The collegiate church of Saint-Étienne at Neuvy-Saint-Sépulchre (Department of the Indre, France is one of the few surviving rotundas built as a copy of the Holy-Sepulcre of Jerusalem during the mid 11th century. Many theories have been advanced concerning the history and the dating of this unusual monument. A recent building survey, carried out during restoration work, has managed to clarify the main phases of its evolution. The rotunda, with eleven central pillars placed around the reliquary monument, was added onto the west end of an existing church during the 1040’s. The two upper stories of the central cage, however, were not finished until the early 12th century. During the second half of the 12th century, the church was extensively

Gravimetric structure for the abyssal mantle massif of Saint Peter and Saint Paul peridotite ridge, Equatorial Atlantic Ocean, and its relation to active uplift

Directory of Open Access Journals (Sweden)

KENJI F. MOTOKI

2014-06-01

Full Text Available This paper presents gravimetric and morphologic analyses based on the satellite-derived data set of EGM2008 and TOPEX for the area of the oceanic mantle massif of the Saint Peter and Saint Paul peridotite ridge, Equatorial Atlantic Ocean. The free-air anomaly indicates that the present plate boundary is not situated along the longitudinal graben which cuts peridotite ridge, but about 20 km to the north of it. The high Bouguer anomaly of the peridotite ridge suggests that it is constituted mainly by unserpentinised ultramafic rocks. The absence of isostatic compensation and low-degree serpentinisation of the ultramafic rocks indicate that the peridotite ridge is sustained mainly by active tectonic uplift. The unparallel relation between the transform fault and the relative plate motion generates near north-south compression and the consequent tectonic uplift. In this sense, the peridotite massif is a pressure ridge due to the strike-slip displacement of the Saint Paul Transform Fault.

Nuclear safety and radiation protection report of the Saint-Alban-Saint-Maurice nuclear facilities - 2011

International Nuclear Information System (INIS)

2012-01-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the facilities of the Saint-Alban-Saint-Maurice nuclear power plant (INB 119 and 120, Isere (FR)). Then, the nuclear safety and radiation protection measures taken regarding the facilities are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2011, are reported as well as the radioactive and non-radioactive (chemical, thermal) effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facilities are presented and sorted by type of waste, quantities and type of conditioning. Other environmental impacts (noise) are presented with their mitigation measures. Actions in favour of transparency and public information are presented as well. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

Nuclear safety and radiation protection report of the Saint-Alban-Saint-Maurice nuclear facilities - 2010

International Nuclear Information System (INIS)

2011-06-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the facilities of the Saint-Alban-Saint-Maurice nuclear power plant (INB 119 and 120, Isere (FR)). Then, the nuclear safety and radiation protection measures taken regarding the facilities are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, are reported as well as the radioactive and non-radioactive (chemical, thermal) effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facilities are presented and sorted by type of waste, quantities and type of conditioning. Other environmental impacts (noise) are presented with their mitigation measures. Actions in favour of transparency and public information are presented as well. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

Changes in the Population Distribution and Transport Network of Saint Petersburg

Directory of Open Access Journals (Sweden)

Xiaoling Li

2016-12-01

Full Text Available The authors explores the interdependence between demographic changes and transport network centrality, using Saint Petersburg as an example. The article describes the demographic data for the period 2002—2015 and the transportation network data of 2006. The authors employ several methods of demographic research; they identified the centre of gravity of the population, produce the standard deviational ellipsis and use the kernel density estimation. The street network centrality of Saint Petersburg was analyzed using the Multiple Centrality Assessment Model (MCA and the Urban Network Analysis Tool for ArcGIS. The analysis of the population distribution in Saint Petersburg shows that each area of the city has seen their population grow over the last thirteen years. However, it is the population of suburban areas that increased the most. The core area of the city has the tendency of outward diffusion, and the population gravity centre has been moving northwards. Spatial characteristics of the population growth, changes in the population gravity centre, the standard deviational ellipse and characteristics of the street network centrality show that Saint Petersburg is at the final stage of urbanization and its development pattern is similar to that of other major cities.

The harmonious relationship between faith and science from the perspective of some great saints: A brief comment.

Science.gov (United States)

Cortés, Manuel E; Del Río, Juan Pablo; Vigil, Pilar

2015-02-01

The objective of this editorial is to show that a harmonious relationship between science and faith is possible, as exemplified by great saints of the Catholic Church. It begins with the definitions of science and faith, followed by an explanation of the apparent conflict between them. A few saints that constitute an example that a fruitful relationship between these two seemingly opposed realities has been possible are Saint Albert the Great, Saint John of the Cross, Saint Giuseppe Moscati, and Saint Edith Stein, among others, and this editorial highlights their deep contributions to the dialogue between faith and reason. This editorial ends with a brief discussion on whether it is possible to be both a scientist and a man of faith.

Energy Transition Initiative: Island Energy Snapshot - Saint Martin/Sint Maarten

Energy Technology Data Exchange (ETDEWEB)

2015-09-01

This profile provides a snapshot of the energy landscape of the northeast Caribbean island Saint Martin. The island is divided between two nations, France in the north (Saint-Martin) and the Netherlands in the south (Sint Maarten).

Malignant melanoma arising in congenital melanocytic nevi: clinical and dermoscopic challenges

Directory of Open Access Journals (Sweden)

Fatma Pelin Cengiz

2017-01-01

Full Text Available Congenital melanocytic nevi (CMN are visible pigmented lesions in the skin that are present at birth. CMN are benign malformations resulting from defective development of melanocyte precursors in the embryo. Six MMs from six patients were analyzed by clinical and dermoscopic examination. Of the patients, 33.3% were female (N = 2 and 66.6% were male (N = 4. Of the MMs, four (66.6% were superficial spreading MM and two (33.3 % were in situ MM. A reticular pattern was present in the MMs of three patients (50%, a homogeneous pattern was present in the other patients (50% at the base of the MMs. Superficial spreading melanomas and in situ melanomas with atypical dots and globules and a blue-white veil were the most common dermoscopic features of MMs found in CMN.

Bathymetry of Lake Erie and Lake Saint Clair

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Bathymetry of Lake Erie and Lake Saint Clair has been compiled as a component of a NOAA project to rescue Great Lakes lake floor geological and geophysical data and...

A New Pilgrimage in Portugal: Following the Steps of Saint Nuno

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Carla Braga

2013-12-01

Full Text Available Tourism is an ever-changing reality. Pilgrimages need different stimuli to attract new followers. In this context we propose to create an itinerary following the steps of Saint Nuno of Santa Maria, canonized in 2009. Nuno Álvares Pereira was the real name of Saint Nuno, who was granted the title Constable of Portugal, and became a historic legend in the independence wars of Portugal during the political crisis of 1383-1385. After fighting against the power of Castile (Spain he decided to devote his life to religion as a Carmelite Friar. He represents the perfect hero of the Middle Ages - associating military prowess with a religious character. Our proposal is to create a religious itinerary based on facts of Saint Nuno’s life, so that any visitor may easily discover the country following the steps of this saint who was deeply devoted to the Virgin - in fact, all temples he founded and restored were dedicated to Our Lady. One of his most famous foundations is the Carmelite Convent in Lisbon, which long after his death was an outstanding popular pilgrimage place, and today is still a strong visitor attraction. This exploratory study is based on literature review and text analyses about religious tourism, itinerary design and the life of the saint. The fieldwork includes acknowledging the different sites related to the saint. We believe that it is possible to create an original religious itinerary in Portugal, which will attract not only foreigners but also domestic visitors, increasing the ‘Production and Consumption of the Pilgrimage Tourism Experience’.

Microseismic noise in the Saint Peter and Saint Paul Archipelago, equatorial Atlantic

Science.gov (United States)

de Queiroz, Daniel É.; do Nascimento, Aderson F.; Schimmel, Martin

2017-12-01

Microseismic noise, also known as ambient seismic noise, are continuous vibrations mostly composed of Rayleigh waves pervasively recorded in the mili Hertz to 1 Hz frequency range. Their precise source mechanisms are under investigations and related to atmospheric perturbations and ocean gravity waves. Our purpose is to show the behavior of the microseismic noise recorded in the Saint Peter and Saint Paul Archipelago (SPSPA) with respect to wind intensity and ocean waves height in this region, between the North and South Atlantic Ocean. We have recorded both primary microseisms (PM) 0.04-0.12 Hz and the secondary microseisms (SM) 0.12-0.4 Hz during almost four years (2012-2015) and we used frequency, temporal, spatial and statistical correlation analysis to do qualitative and quantitative analysis with respect to wind speed intensity and significant wave height for the same periods. The results indicate a good correlation between the PM and the SM noise in the region particularly during the winter in the Northern Hemisphere and a poor correlation during the summer. We have also shown that probably most of the PM are generated in the SPSPA itself. We note that the intensity of SM recorded in SPSPA appears to have a seasonal behavior with the summer and winter in the Northern Hemisphere, and seems to influence the correlation between the PM and the SM, suggesting that the sources of the PM and the SM are not related to the same atmospheric event and from different places. PM generation would occur near the SPSPA whilst the SM would have distant sources towards the North Atlantic.

Global Culture, Island Identity: Continuity and Change in the Afro-Caribbean Community of Nevis by Karen Fog Olwig

OpenAIRE

Maurer, WM

1995-01-01

This important book sheds light on the interplay of hierarchy and equality, the local and the global, and the Caribbean and the European in the cultural history of Nevis. In addition to bringing recent theoretical concerns with transnationalism and identity to Caribbean studies, Karen Olwig directs Caribbean ethnology away from static conceptions of kinship and household, religion and social life, and African cultural retentions, and toward an integration of kinship, gender,...

the vision of divine light in saint gregory palamas's theology

African Journals Online (AJOL)

in Romania. 2. THE RECEPTION OF SAINT GREGORY PALAMAS'S. THEOLOGY IN THE WEST. In the West, the reception of Saint Gregory Palamas's theology, as it is known, was rather a negative one. His doctrine of divine light was rejected, because it postulated the possibility of seeing God with corporeal eyes. (Lossky ...

Les couleurs de Moscou et de Saint-Pétersbourg The colours of Moscow and Saint Petersburg

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Andréi Éfimov

2008-05-01

Full Text Available Moscou et Saint-Pétersbourg ont connu une évolution chromatique similaire mais les différences en matière de plan, d’urbanisme et d’influences culturelles, et leurs rôles alternés de capitale ont déterminé leurs particularités chromatiques propres. Le Moscou en bois du xiiie siècle s’est enrichi d’un ensemble de cathédrales blanches aux coupoles dorées entourées par la muraille en brique rouge du Kremlin. Le style baroque a introduit dans l’architecture de Moscou et de Saint-Pétersbourg les couleurs bleu foncé, orange et verte. À l’époque du classicisme, on utilisait la palette officielle de teintes pastel à dominante ocre. L’achromatisme devient ensuite un trait distinctif de l’éclectisme en Russie. Au début du XXe siècle, l’Art nouveau ranime les villes grâce aux couleurs verte, orange et violette. Dans les années 1920 et 1930, les constructivistes utilisent les tons gris mais tentent d’élaborer un code chromatique homogène. L’architecture soviétique, quant à elle, reprend l’esthétique du classicisme « ocre ». La construction de masse des années 1960 aux années 1980 méconnaît la couleur, mais à la charnière des XXe et XXIe siècles apparaissent des approches professionnelles qui visent à créer un milieu chromatique similaire pour les deux villes.Moscow and Saint Petersburg experienced similar evolutions in colour, but the differences in their plans, urbanity and cultural influences, and their alternating roles as capitals, determined the particularities of their palettes. The wooden Moscow of the thirteenth century was enriched by a group of white cathedrals with golden domes, surrounded by the red brick wall of the Kremlin. Baroque, as an architectural style, introduced Moscow and Saint Petersburg to the colours dark blue, orange, and green. The official palette of classicism was pastel, predominantly ochre, while the period of eclecticism in Russia was achromatic. At the

Melanoma and melanocytic nevi in decorative tattoos: three case reports.

Science.gov (United States)

Varga, Erika; Korom, Irma; Varga, János; Kohán, József; Kemény, Lajos; Oláh, Judit

2011-12-01

In response to the demands of style and fashion, the number of decorative tattoos has been increasing worldwide. This has been paralleled by a rising incidence of melanocytic proliferations, including melanoma. The coincidence of various dermatological diseases and skin tumors with tattoos has been documented with some frequency, but reports of melanoma associated with tattoos are exceedingly rare. To date, only 13 cases have been documented in the English language literature. The possibility of an association between melanocytic proliferations and tattoos remains an area for further study. This report presents two cases of melanocytic nevi and one of melanoma occurring in association with a decorative tattoos. At present, the pathogenesis of melanoma developing in a tattoo is unknown. Mere coincidence cannot be ruled out. However, trauma, ultraviolet light exposure, a photoallergic effect, or an inflammatory reaction may promote malignant transformation. Clinicians and histopathologists should be aware of the clinical and pathological features if they are to make a correct diagnosis. Copyright © 2011 John Wiley & Sons A/S.

MicroRNA expression in melanocytic nevi: the usefulness of formalin-fixed, paraffin-embedded material for miRNA microarray profiling

DEFF Research Database (Denmark)

Glud, M.; Klausen, M.; Gniadecki, R.

2009-01-01

surgical specimens are formalin fixed and paraffin embedded (FFPE). To explore whether FFPE material would be suitable for miRNA profiling in melanocytic lesions, we compared miRNA expression patterns in FFPE versus fresh frozen samples, obtained from 15 human melanocytic nevi. Out of microarray data, we...

Particular intervention plan of the Saint Alban-Saint Maurice l'Exil Nuclear Power Plant

International Nuclear Information System (INIS)

2010-01-01

The Particular intervention plan (PPI in French) is an emergency plan which foresees the measures and means to be implemented to address the potential risks of the presence and operation of a nuclear facility. This plan is implemented and developed by the Prefect in case of nuclear accident (or incident leading to a potential accident), the impact of which extending beyond the facility perimeter. It represents a special section of the organisation plan for civil protection response (ORSEC plan). The PPI foresees the necessary measures and means for crisis management during the first hours following the accident and is triggered by the Department Prefect according to the information provided by the facility operator. Its aim is to protect the populations leaving within 10 km of the facility against a potential radiological hazard. The PPI describes: the facility, the intervention area, the protection measures for the population, the conditions of emergency plan triggering, the crisis organisation, the action forms of the different services, and the post-accident stage. This document is the public version of the Particular intervention plan of the Saint Alban-Saint Maurice NPP (Isere, France)

Clinical and Pathologic Findings of Spitz Nevi and Atypical Spitz Tumors with ALK Fusions

Science.gov (United States)

Busam, Klaus J; Kutzner, Heinz; Cerroni, Lorenzo; Wiesner, Thomas

2016-01-01

Spitz tumors represent a group of melanocytic neoplasms that typically affects young individuals. Microscopically the lesions are composed of cytologically distinct spindle and epithelioid melanocytes, with a range in the architectural display or the cells, their nuclear features, and secondary epidermal or stromal changes. Recently, kinase fusions have been documented in a subset of Spitz tumors, but there is limited information on the clinical and pathologic features associated with those lesions. Here, we report a series of 17 patients (9 male, 8 female) with spitzoid neoplasms showing ALK fusions (5 Spitz nevi and 12 atypical Spitz tumors). The patients’ ages ranged from 2 years to 35 years (mean = 17; median = 16). Most lesions were located on the lower extremities and presented clinically as polypoid nodules. All tumors were compound melanocytic proliferations with a predominant intradermal growth. Tumor thickness ranged from 1.1 to 6 mm (mean = 2.9 mm; median = 2.5 mm). The most characteristic histopathologic feature of the tumors (seen in all but two lesions) was a plexiform dermal growth of intersecting fascicles of fusiform melanocytes. All but two tumors were amelanotic. All tumors were strongly immunoreactive for ALK. The ALK rearrangements were confirmed in all cases by fluorescence in situ hybridization (FISH) and the fusion partner was determined by quantitative polymerase chain reaction as TPM3 (tropomyosin 3) in 11 cases and DCTN1 (dynactin 1) in 6 cases. None of the eight tumors, which were analyzed by FISH for copy number changes of 6p, 6q, 9p, or 11q met criteria for melanoma. Two patients underwent a sentinel lymph node biopsy, and in both cases melanocytes nests were found in the subcapsular sinus of the node. Array comparative genomic hybridization of these two tumors revealed no chromosomal gains or losses. In conclusion, our study revealed that Spitz nevi/tumors with ALK rearrangement show a characteristic plexiform morphology and that

Thinking with the saint: the miracle of Saint Januarius of Naples and science in early modern Europe.

Science.gov (United States)

de Ceglia, Francesco Paolo

2014-01-01

The aim of this paper is to reconstruct the way in which early modem science questioned and indirectly influenced (while being in its turn influenced by) the conceptualization of the liquefaction of the blood of Saint Januarius, a phenomenon that has been taking place at regular intervals in Naples since the late Middle Ages. In the seventeenth century, a debate arose that divided Europe between supporters of a theory of divine intervention and believers in the occult properties of the blood. These two theoretical options reflected two different perspectives on the relationship between the natural and the supernatural. While in the seventeenth century, the emphasis was placed on the predictable periodicity of the miraculous event of liquefaction as a manifestation of God in his role as a divine regulator, in the eighteenth century the event came to be described as capricious and unpredictable, in an attempt to differentiate miracles from the workings of nature, which were deemed to be normative. The miracle of the blood of Saint Januarius thus provides a window through which we can catch a glimpse of how the natural order was perceived in early modern Europe at a time when the Continent was culturally fragmented into north and south, Protestantism and Catholicism, learned and ignorant.

A Latter-day Saint Approach to Addiction: Aetiology, Consequences and Treatment in a Theological Context

Directory of Open Access Journals (Sweden)

James D. Holt

2014-12-01

Full Text Available This article explores the theological underpinning of the nature, aetiology and treatment of addictions within The Church of Jesus Christ of Latter-day Saints. The first section outlines the “plan of salvation” and how this provides the theological framework for the source and solution to addictions. The final section explores addiction against this background in terms of its aetiology, types, consequences and treatment in a Latter-day Saint context. In so doing it builds on the recognition by the Church in recent years that addiction is a problem in the lives of some of its members and that treatment programs coherent with its teachings and beliefs are necessary. The article concludes by suggesting that while addiction may be more openly discussed within a Latter-day Saint context there is a need to keep this dialogue moving forward. This article does not examine Latter-day Saint teaching within the wider context of psychotherapy and other definitions of addiction; rather it explores the place of addiction as understood within the theological and ecclesiological context of Mormonism.

Saint Lucia revisited.

Science.gov (United States)

Bos, R; Février, M; Knudsen, A B

1988-10-01

The eastern Caribbean island of Saint Lucia is now famous in parasitological history as the setting for a major programme of schistosomiasis control'. Perhaps less well-known are the island's effective control of many intestinal parasites, and elimination of malaria, such that the current patterns of mortality and other demographic indicators now resemble those of industrialized countries. More recently, the island has become the focus for another community-based health programme as the Caribbean region again comes to grips with Aedes aegypti and its recently imported relative, Aedes albopictus, important vectors of yellow fever and dengue viruses (see Box 1).

Please exercise extreme caution at the Saint-Genis roundabout

CERN Multimedia

2015-01-01

In the interests of enhanced safety, a new pathway for pedestrians and cyclists has been constructed around the outside of the Saint-Genis roundabout. However, the markings of the previous cycle path, which is now closed to traffic, are still visible and can cause confusion. We therefore call on everyone to exercise extreme caution and to use the new pathway.   New two-way markings have been laid out, inviting pedestrians and cyclists coming from the direction of Saint-Genis-Pouilly to go towards the Swiss border or CERN Entrance E using the left-hand side of the roundabout (i.e. the Prévessin side). So, from now on, cyclists must no longer go around the roundabout on the right-hand side and pedestrians will no longer have to cross the D884 dual carriageway. Similarly, people staying at the Saint-Genis hostel are invited to follow these new markings to get to CERN or to return to the hostel, which means they will avoid having to cross the D35 highway at a spot where traffic is...

Sanctified madness: the God-intoxicated saints of Bengal.

Science.gov (United States)

Morinis, A

1985-01-01

The saintly madman is a familiar character in South Asia. To outer appearances he is no different from a lunatic, but the mad saint comes to be revered because his idiocy is popularly believed to arise from a different cause than ordinary madness. The common psychopath neglects social conventions because his consciousness is dimmed by incapacity; the saintly madman also breaches convention, but does so because his heightened consciousness has liberated him from the bonds of convention that entrap ordinary people. In the terms of Hinduism, he has tasted the divine nectar of God-realization and has returned to the human realm intoxicated by the experience. In this paper two popular God intoxicated saints of Bengal are discussed. The question is posed whether 'God intoxication' can be considered a culture-bound syndrome of Bengal. The concept of 'culture bound syndrome' is found to be too narrow to encompass the most significant issues to arise from reflection on the characteristics of the God intoxicated. These larger issues have to do with the relationship between cultural practices and models and mental states (whether deviant, as implied by the term 'syndrome' although deviance does not always carry the negative connotation implicit in 'syndrome', or normal). It is suggested that all cultures culture a limited range of mental states and thus the questions posed by the notion of culture bound syndromes are subsumed by larger questions about the relationship of all mind-states to the socio-cultural environment which conditions them. The conclusion is that God intoxication is indeed a uniquely Bengali mental condition, with variants throughout South Asia and kinship to other mystical states, but that the concept of 'syndrome' is not useful.

SUFI SAINTS IN KARNATAKA

Directory of Open Access Journals (Sweden)

Maruti KAMBLE

2011-01-01

Full Text Available Karnataka is one of the most important southern states of India. It has gainedprominence politically, socio-economically, philosophically and in many otherways. It is a meeting place of many religious philosophies and a melting pointhelping to achieve the synthesis of the teaching ofmany religious reforms. Sufismis a mystic religion. It is an offshoot of Islam. Sufi saints are the followers ofALLAH and the practice of peace, benevolence and tolerance. They promulgateda religion based on the concept of love, the love with the fellow being and thelove with the ultimate or the creator. Sufi saintsand Sufism are an existing realityin Indian socio-religious fold and it has contributed for a healthy and amicablesocial order. It has lead to a new social set-up full of values, and discipline.Sufism as a religion of the teaming millions becamethe practicing system amongthe people of India as well as Karnataka. This study of Sufi Saints in Karnataka isthus an inspired attempt to portray this religion of the soul and heart. Muchemphasis is laid on the concepts and special aspects of Sufism, along with variouspractices found in it. I was always attracted by its spiritual significance andpractical essence and also its profound influence on the general public. Hence, mylittle attempt to explain the same through the lifestories of some of the great Sufisaints in Karnataka.

Contextualising and Visualising Saints in the 14-15th century

Czech Academy of Sciences Publication Activity Database

Horníčková, Kateřina

-, č. 62 (2011), s. 21-39 ISSN 1029-0737 Institutional research plan: CEZ:AV0Z90090514 Keywords : medieval art * saints' representation * representation of place Subject RIV: AA - Philosophy ; Religion

Virological Surveillance of Dengue in Saint Martin and Saint Barthélemy, French West Indies, Using Blood Samples on Filter Paper

Science.gov (United States)

Matheus, Séverine; Chappert, Jean-Loup; Cassadou, Sylvie; Berger, Franck; Labeau, Bhetty; Bremand, Laetitia; Winicki, Alain; Huc-Anais, Patricia; Quenel, Philippe; Dussart, Philippe

2012-01-01

To strengthen active dengue surveillance in Saint Martin and Saint Barthélemy, two French Caribbean islands, we evaluated the epidemiological usefulness of collecting blood samples from NS1-positive dengue patients on filter paper to identify the dengue serotypes circulating in these regions during a 27-month period. This approach allowed dengue serotypes to be identified by reverse transcriptase-polymerase chain reaction in 90.1% of the total set of 666 samples analyzed and, in 95.5% of the samples collected during the acute phase of the disease. This prospective virological surveillance using blood samples absorbed onto filter paper, which were stored at 4°C and shipped at ambient temperature to a specialized laboratory for analysis, allowed us to avoid the logistic and financial costs associated with shipping frozen venous blood samples. This surveillance system offers a low-cost alternative for reinforcing dengue prevention in areas where specialized laboratories do not exist, notably by facilitating the early detection of potentially new dengue serotypes. PMID:22232467

Fenbendazole treatment for Mammomonogamus species infection of a domestic cat on St Kitts, West Indies.

Science.gov (United States)

Gattenuo, Talia; Ketzis, Jennifer; Shell, Linda

2014-10-01

A 7-month-old, female, domestic shorthair, indoor/outdoor cat on the island of St Kitts was presented to the Veterinary Teaching Hospital at Ross University School of Veterinary Medicine as part of a student training spay-neuter program. Observation of diarrhea prompted a double centrifugation fecal analysis. Ova of Mammomonogamus species, in addition to Ancylostoma species, Trichuris species and Platynosomum species, were found. Mammomonogamus ierei is a parasitic nematode found on many Caribbean islands for which treatment is not well documented. Five days of fenbendazole (50 mg/kg bodyweight) was administered, and fecal analyses gave negative results for Mammomonogamus species eggs 1 week after the last fenbendazole treatment. © ISFM and AAFP 2014.

The implantation of a PV electric energy generation system at the Saint Peter and Saint Paul islands

Energy Technology Data Exchange (ETDEWEB)

Galdino, Marco Antonio; Silva, Patricia de Castro da [Centro de Pesquisas de Energia Eletrica (CEPEL), Rio de Janeiro, RJ (Brazil)], E-mail: marcoag@cepel.br; Souza, Marco Antonio Carvalho [Secretaria da Comissao Interministerial para os Recursos do Mar (SECIRM), Brasilia, DF (Brazil)

2009-07-01

The Saint Peter and Saint Paul Islands are located at 0 degree 55.00' N and 29 degree 20.76'' W, at a distance of circa 550 M (nautical miles) NE from the City of Natal, RN (Northeast Region of Brazil), and comprises of many small islands and rocks of igneous plutonic origin. In 1998, a first Scientific Station was built in order to receive researchers involved in several projects. The CEPEL, as responsible by the electrical energy supply to the Scientific Station; designed and installed a PV electric energy generation system which had a power of 3.6 kWp. This system operated successfully for the last 10 years, suffering frequent maintenance. In 2006, a new design for the Scientific Station has been started aiming to improve its resources and safety. The new PV system has a maximum power of 7.8 kWp, and employs an updated technology (SMA, Germany). The equipment was integrated and submitted to intensive testing at facilities of CEPEL, and was installed and commissioned at the Islands in June 2008. Since the installation, the equipment has been operating as required, meeting the energy and water demand of the Station. The present paper describes the many steps involved in the implantation of the PV system at the Scientific Station. (author)

President Ilves kõneles Saint Gallenis

Index Scriptorium Estoniae

2009-01-01

President Toomas Hendrik Ilves esines 9. mail 2009 Šveitsis, Saint Galleni 39. majandus- ja poliitikasümpoosionil kõnega teemal "20 aastat pärast Berliini müüri langemist - Euroopa uued väljakutsed". Vabariigi President töövisiidil Šveitsis 08.-09.05.2009

Impact of bacteriophage Saint3 carriage on the immune evasion capacity and hemolytic potential of Staphylococcus aureus CC398.

Science.gov (United States)

Jung, Philipp; Abdelbary, Mohamed M H; Kraushaar, Britta; Fetsch, Alexandra; Geisel, Jürgen; Herrmann, Mathias; Witte, Wolfgang; Cuny, Christiane; Bischoff, Markus

2017-02-01

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates of clonal complex 398 (CC398) are frequently found in Europe, and recent studies highlighted the importance of mobile genetic element (MGE) exchange for host adaptation of this lineage. Of note, one of the MGEs commonly found in human S. aureus isolates, the immune evasion cluster (IEC) harboring bacteriophage Saint3, is very rarely found in LA-MRSA CC398 isolates obtained from farm animals, but more frequently found in LA-MRSA CC398 that were retransmitted to humans. Here, we analyzed with a set of S. aureus CC398 isolates harboring/lacking φSaint3 how this MGE affects (i) phagocytosis of CC398 isolates by polymorphonuclear neutrophils (PMNs), and (ii) hemolysis of human and livestock-derived erythrocytes. Isolates lacking φSaint3 were more efficiently phagocytosed by human PMNs in whole blood phagocytosis assays than isolates harboring this bacteriophage, irrespective of their origin. Notably, a similar effect was observed when equine blood was utilized, but not detected with porcine blood. Integration of φSaint3 into LA-MRSA CC398 strains lacking this MGE confirmed these findings, as φSaint3-harboring recipients were again less efficiently ingested by PMNs in equine and human blood than their parental strains. Integration of φSaint3 strongly reduced the hemolytic potential of the culture supernatants against human-derived erythrocytes, and to a smaller extent also against porcine-derived erythrocytes, while φSaint3 integration only slightly affected the hemolytic capacities against equine-derived red blood cells. The significant protective effect of φSaint3 against phagocytosis by equine PMNs suggests that the host specificity of the IEC components might be broader than currently assumed. Copyright © 2016 Elsevier B.V. All rights reserved.

Life and death at precolumbian Lavoutte, Saint Lucia, Lesser Antilles

NARCIS (Netherlands)

Hofman, C.L.; Hoogland, M.L.P.; Mickleburgh, H.L.; Laffoon, J.E.; Weston, D.A.; Field, M.H.

2012-01-01

The Caribbean archaeological record requires immediate attention and protection. Development and natural forces have impacted archaeological sites, destroying or severely damaging them. The precolumbian site of Lavoutte, located in northern Saint Lucia, has been known as a major Late Ceramic Age

Rare copy of "Life of Saint Volo-dymyr" (Kyiv, 1670 from the manuscript Corpus of Lives of the Saints as a source for the 17th century Kyiv hagiography study

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Bondar N. P.

2017-01-01

Full Text Available In the article a rare copy of an old-printed edition of “Life of Saint Volodymyr”, published circa 1670 in the Kyiv-Pechersk Lavra printing-house is characterized. The copy was included to Corpus of Lives of the Saints of the17th-18th centuries from the collection of Church and Archeological museum of Kyiv Ecclesiastical Academy (Fond 301, Unit 416L. According to the modern advances of codicology, archeology, filigranology it became possible to critically review the data of descriptions, which brought new results. The approximate dating of the old-printed edition, which has no title and imprint, is confirmed. The publishing history of “Life of Saint Volodymyr” is analyzed. The research of the copy is accompanied by the complex description of overall manuscript hagiography codex, the analysis of its content, specifics, ownership notes and paper filigrees. Archeographic analysis of Corpus of Lives of the Saints was combined with study of formation of Ukrainian hagiography complex of the second half of the 17th - the early 18th centuries.

Evaluation of OPPS model for plant operator's task simulation with Micro-SAINT

International Nuclear Information System (INIS)

Yoshida, Kazuo

1991-03-01

The development of a computer simulation method for cognitive behavior of operators under emergency conditions in nuclear power plant are being conducted at Japan Atomic Energy Research Institute (JAERI). As one of activities in this project, the task network modeling and simulation method has been evaluated with reproduced OPPS model using Micro-SAINT which is a PC software for task network analysis. OPPS is an operator's task simulation model developed by Oak Ridge National Laboratory. Operator's tasks under the condition of failure open of a safety relief valve in a BWR power plant has been analyzed as a sample problem with Micro-SAINT version of OPPS for the evaluation of task network analysis method. Furthermore, the fundamental capabilities of Micro-SAINT has been evaluated, and the task network in OPPS model has been also examined. As the results of this study, it has been clarified that random seed numbers in Micro-SAINT affect the probabilistic branching ratio and the distribution of task execution time calculated by Monte Carlo simulations, and the expression of network for a repeated task in the OPPS model leads to incorrect standard deviation in the case that a task execution time has some distribution. (author)

Colourful sparkles of imaginary vistas: Saintly beauty in the eyes of the beholder

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Dimitrova Elizabeta

2013-01-01

Full Text Available The article deals with the issue of physical appearance of the saintly images in Byzantine painting and the manners of its conception. In that regard, the paper offers categorization of the portraiture in which different saints receive distinctive aesthetic code appropriate to their type of “attractiveness”.

The Segmented Aperture Interferometric Nulling Testbed (SAINT) I: overview and air-side system description

Science.gov (United States)

Hicks, Brian A.; Lyon, Richard G.; Petrone, Peter; Ballard, Marlin; Bolcar, Matthew R.; Bolognese, Jeff; Clampin, Mark; Dogoda, Peter; Dworzanski, Daniel; Helmbrecht, Michael A.; Koca, Corina; Shiri, Ron

2016-07-01

This work presents an overview of the Segmented Aperture Interferometric Nulling Testbed (SAINT), a project that will pair an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC). SAINT will incorporate the VNC's demonstrated wavefront sensing and control system to refine and quantify end-to-end high-contrast starlight suppression performance. This pathfinder testbed will be used as a tool to study and refine approaches to mitigating instabilities and complex diffraction expected from future large segmented aperture telescopes.

What Are Robespierre and Telemachus Doing in Saint-Domingue?

DEFF Research Database (Denmark)

Kjærgård, Jonas Ross

2018-01-01

Charles Pigault-Lebrun's play Le blanc et le noir (1795) is one of only a handful of French revolutionary plays to stage the Saint-Domingue slave rebellion, a rebellion today better known as the Haitian Revolution (1791–1804). I argue that Pigault-Lebrun uses early melodramatic generic traits to ...

Des saints pour la fiction, des saints face à l’Histoire

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Aude Bonord

2008-12-01

Full Text Available Pourquoi des écrivains non confessionnels (Joseph Delteil, Blaise Cendrars, Christian Bobin, Sylvie Germain, Claude Louis-Combet ont-ils choisi de réécrire des vies de saints au XXe siècle ? Le parti pris est surprenant à plusieurs titres. L’hagiographie est un genre historique et religieux, terrain a priori réservé aux historiens, aux ecclésiastiques ou aux écrivains catholiques. De plus, à la fin du siècle, l’hagiographie est sortie du champ littéraire avec la disparition du groupe des écrivains catholiques. Curieusement, nos auteurs vont s’inscrire dans ces décalages non seulement pour définir leur place par rapport à l’hagiographe traditionnel mais aussi pour s’approprier le genre. Amorces fictionnelles et objets de rêveries poétiques, les vies de saints sont soumises à la fantaisie littéraire de ces auteurs au statut improbable. Dans un dialogue avec les sources allant du jeu à la contestation, les écrivains utilisent l’intertexte hagiographique, et notamment son système narratif, pour s’évader dans le merveilleux mais encore pour penser leur époque. En effet, si éloignée de la réalité contemporaine soit-elle en apparence, l’hagiographie joue à la fois un rôle de contrepoint et de reflet du présent. La confrontation avec ces récits surgis du passé permet alors aux auteurs de repenser la marche de l’Histoire et l’inscription de l’Homme dans le temps.

[Saints and illnesses in faith and paleopathological evidences].

Science.gov (United States)

Fulcheri, Ezio

2006-01-01

The exhumation of the natural mummies of Beata Margherita di Savoia (1390-1464) and of St. Caterina Fieschi Adorno (1447-1510) has not been followed by autopsy or histological exams. The aim has been to preserve the integrity of the saints' corpses. We have thus proceeded to a confrontation between data gathered from chronicles and hagiographies and radiological exams and macroscopic observations. The article aims at establishing a model for a multidisciplinar approach to paleopathological research, integrating historical research and medical knowledge.

The Slavonic Translation of the Life of Saint Euthymius the Great: Observations on Language and Authorship

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Dmitriy Evgenyevich Afinogenov

2015-10-01

Full Text Available The Slavonic translation of the Life of Saint Euthymius the Great (BHG 647 by Cyril of Scythopolis, attested at the earliest manuscript of the late 14th c., was probably made by a person originating from South-East Rus in the 11th c., as it displays some grammatical, lexical, and phonetic features peculiar for this area and time, and visible, in particular, in Ipatiev Chronicle and the Tale of Igor’s Campaign. It may have formed a part of the collection comprising several writings by Cyril, including the Life of Saint Sabas and the Praise of Euthymius and Sabas (lost in the Greek original. This collection was later incorporated into the Great Lectionary Menologion of Metropolitan Makarij. The details added by the translator to the description of certain realia pertaining to the Monastery of Saint Euthymius in Palestine suggest a personal knowledge of that monastic complex (the Laura and the coenobium. The proposed author of the translation is Saint Anthony of the Cave Monastery in Kiev († 1073, who could perfectly well have visited the Holy Land during his stay on Mount Athos prior to 1051.

Egg deposition by lithophilic-spawning fishes in the Detroit and Saint Clair Rivers, 2005–14

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Prichard, Carson G.; Craig, Jaquelyn M.; Roseman, Edward F.; Fischer, Jason L.; Manny, Bruce A.; Kennedy, Gregory W.

2017-03-14

A long-term, multiseason, fish egg sampling program conducted annually on the Detroit (2005–14) and Saint Clair (2010–14) Rivers was summarized to identify where productive fish spawning habitat currently exists. Egg mats were placed on the river bottom during the spring and fall at historic spawning areas and candidate fish spawning habitat restoration sites throughout both rivers. Widespread evidence was found of lithophilic spawning by numerous native fish species, including walleye (Sander vitreus), lake whitefish (Coregonus clupeaformis), lake sturgeon (Acipenser fulvescens), suckers (Catostomidae spp.), and trout-perch (Percopsis omiscomaycus). Walleye, lake whitefish, and suckers spp. spawned in nearly every region of each river in all years on both reef and nonreef substrates. Lake sturgeon eggs were collected almost exclusively over constructed reefs. Catch-per-unit effort of walleye, lake whitefish, and sucker eggs was much greater in the Detroit River than in the Saint Clair River, while Saint Clair River sites supported the greatest collections of lake sturgeon eggs. Collections during this study of lake sturgeon eggs on man-made spawning reefs suggest that artificial reefs may be an effective tool for restoring fish populations in the Detroit and Saint Clair Rivers; however, the quick response of lake sturgeon to spawn on newly constructed reefs and the fact that walleye, lake whitefish, and sucker eggs were often collected over substrate with little interstitial space to protect eggs from siltation and predators suggests that lack of suitable spawning habitat may continue to limit reproduction of lithophilic-spawning fish species in the Saint Clair-Detroit River System.

The Way of Saint James and the Xacobeo 2010 in the tourism websites of the Spanish autonomous communities

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María-Dolores Fernández-Poyatos, Ph.D.

2012-01-01

Full Text Available This article analyses the tourism websites of Spanish autonomous communities crossed by the Way of Saint James. Considering that the Way of Saint James and the Xacobeo 2010 are important touristic opportunities for these autonomous regions, the main objective of this investigation is to evaluate the information about these touristic places in their tourism websites. The analysis focused on two aspects: firstly, establishing whether the autonomous communities have used the Way of Saint James and the Xacobeo 2010 to promote themselves, and secondly, evaluating the quality of the websites. The study included a literature review, definition of concepts and criteria to measure the quality of websites, and the analysis of the content and design of the selected tourism websites. The results show that the Galician website is the most complete in terms of information about the Way of Saint James and the Xacobeo 2010. The information about the Way of Saint James and the Xacobeo 2010 in the websites of the other communities is vague and differs from one website to another. Due to the touristic significance of the Xacobeo 2010 and the importance of Internet as a medium of communication, the research group plans to conduct a new analysis of the communities’ institutional websites in 2011.

Marketing analysis of brand Yves Saint Laurent in portfolio L´Oréal

OpenAIRE

Petránková, Tereza

2011-01-01

The aim of this thesis Marketing analysis of brand Yves Saint Laurent in portfolio L'Oréal is analysis of brand Yves Saint Laurent. The theoretical part focuses mainly on marketing, brand, luxury, analysis of brand and marketing strategies. Practical part based on the findings in theoretical part analysed brand - history, indentity, value and marketing strategy and reccomend new marketing strategies.

Rahmaninov ja Saint-Saens Estonia kontserdisaalis / Tiina Õun

Index Scriptorium Estoniae

Õun, Tiina, 1954-

2005-01-01

18. novembril Estonia kontserdisaalis toimuvast Sergei Rahmaninovi Klaverikontsert nr 2 ja "Kellad" ettekandest ja 29. novembril Toimuvast Camille Saint-Saensi ooperi "Simson ja Delila" kontsertettekandest

Saint-Augustin, Proudhon, antithèses

OpenAIRE

Pasteur , Sébastien

2005-01-01

Proudhon cite peu Saint-Augustin, mais le parallèle d'un contexte historique à son tournant offre matière à réfléchir. D'autant que Proudhon, anticlérical concède au Père de l'Eglise, un rang de philosophe, occasion d'aborder la fondation du discours philosophique au travers de la confession.

THE IMPACT OF SAINT PARASCHEVA PILGRIMAGE ON TOURISM IN IASI COUNTY

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Alexandra Georgiana PARASCA

2015-07-01

Full Text Available Nowadays, pilgrimage is a part of international tourism, being considered religious tourism, because it contributes to the development of economy, like any other type of tourism. This research paper takes into consideration the pilgrimage to Saint Paracheva, and how it helps the development of religious tourism in Iasi county, the economical implications. We try to capture the importance of Saint Parascheva pilgrimage, because year after year it bring many more pilgrims to Iasi city. In time, it could become an important place of pilgrimage at European level.

MicroRNA expression in melanocytic nevi: the usefulness of formalin-fixed, paraffin-embedded material for miRNA microarray profiling.

Science.gov (United States)

Glud, Martin; Klausen, Mikkel; Gniadecki, Robert; Rossing, Maria; Hastrup, Nina; Nielsen, Finn C; Drzewiecki, Krzysztof T

2009-05-01

MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate cellular differentiation, proliferation, and apoptosis. MiRNAs are expressed in a developmentally regulated and tissue-specific manner. Aberrant expression may contribute to pathological processes such as cancer, and miRNA may therefore serve as biomarkers that may be useful in a clinical environment for diagnosis of various diseases. Most miRNA profiling studies have used fresh tissue samples. However, in some types of cancer, including malignant melanoma, fresh material is difficult to obtain from primary tumors, and most surgical specimens are formalin fixed and paraffin embedded (FFPE). To explore whether FFPE material would be suitable for miRNA profiling in melanocytic lesions, we compared miRNA expression patterns in FFPE versus fresh frozen samples, obtained from 15 human melanocytic nevi. Out of microarray data, we identified 84 miRNAs that were expressed in both types of samples and represented an miRNA profile of melanocytic nevi. Our results showed a high correlation in miRNA expression (Spearman r-value of 0.80) between paired FFPE and fresh frozen material. The data were further validated by quantitative RT-PCR. In conclusion, FFPE specimens of melanocytic lesions are suitable as a source for miRNA microarray profiling.

Saint Petersburg magnetic observatory: from Voeikovo subdivision to INTERMAGNET certification

Science.gov (United States)

Sidorov, Roman; Soloviev, Anatoly; Krasnoperov, Roman; Kudin, Dmitry; Grudnev, Andrei; Kopytenko, Yury; Kotikov, Andrei; Sergushin, Pavel

2017-11-01

Since June 2012 the Saint Petersburg magnetic observatory is being developed and maintained by two institutions of the Russian Academy of Sciences (RAS) - the Geophysical Center of RAS (GC RAS) and the Saint Petersburg branch of the Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of RAS (IZMIRAN SPb). On 29 April 2016 the application of the Saint Petersburg observatory (IAGA code SPG) for introduction into the INTERMAGNET network was accepted after approval by the experts of the first definitive dataset over 2015, produced by the GC RAS, and on 9 June 2016 the SPG observatory was officially certified. One of the oldest series of magnetic observations, originating in 1834, was resumed in the 21st century, meeting the highest quality standards and all modern technical requirements. In this paper a brief historical and scientific background of the SPG observatory foundation and development is given, the stages of its renovation and upgrade in the 21st century are described, and information on its current state is provided. The first results of the observatory functioning are discussed and geomagnetic variations registered at the SPG observatory are assessed and compared with geomagnetic data from the INTERMAGNET observatories located in the same region.

Saint Petersburg magnetic observatory: from Voeikovo subdivision to INTERMAGNET certification

Directory of Open Access Journals (Sweden)

R. Sidorov

2017-11-01

Full Text Available Since June 2012 the Saint Petersburg magnetic observatory is being developed and maintained by two institutions of the Russian Academy of Sciences (RAS – the Geophysical Center of RAS (GC RAS and the Saint Petersburg branch of the Pushkov Institute of Terrestrial Magnetism, Ionosphere and Radio Wave Propagation of RAS (IZMIRAN SPb. On 29 April 2016 the application of the Saint Petersburg observatory (IAGA code SPG for introduction into the INTERMAGNET network was accepted after approval by the experts of the first definitive dataset over 2015, produced by the GC RAS, and on 9 June 2016 the SPG observatory was officially certified. One of the oldest series of magnetic observations, originating in 1834, was resumed in the 21st century, meeting the highest quality standards and all modern technical requirements. In this paper a brief historical and scientific background of the SPG observatory foundation and development is given, the stages of its renovation and upgrade in the 21st century are described, and information on its current state is provided. The first results of the observatory functioning are discussed and geomagnetic variations registered at the SPG observatory are assessed and compared with geomagnetic data from the INTERMAGNET observatories located in the same region.

Leptospira seroprevalence in animals in the Caribbean region: A systematic review.

Science.gov (United States)

Pratt, Nicola; Rajeev, Sreekumari

2018-06-01

This systematic review summarises the data published on the Leptospira seroprevalence, serovar diversity and distribution among animal species in the Caribbean region. Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, and checklist, relevant articles were identified and data were extracted and recorded. The review provided Leptospira seroprevalence data from 16 Caribbean islands (Barbados, Trinidad, Grenada, Puerto Rico, Saint Croix, St. Kitts and Nevis, Jamaica, Antigua, Carriacou, Dominica, Guadalupe, Martinique, Monserrat, St. Lucia, St. Maarten, and St. Vincent) in a variety of animal species. Reviewing the literature highlighted the limited amount of data available from limited number of islands. Many of the studies conducted have recorded seroprevalences based on variable and small samples sizes. Besides, serovar panels used for MAT were not consistent between studies. The review indicates that the Leptospira exposure in a given geographic location may change with time and climatic and environmental conditions, and highlights the need to conduct continual surveillance in tropical countries where the climate supports the survival of Leptospira in the environment. Specific attention must be given to standardization of MAT panels and protocols and providing training across laboratories involved in testing. Further, animal and environment testing to isolate and identify circulating Leptospira spp. in a geographic region must actively be pursued. This knowledge is important to implement geographically specific control programs, as risk factors of Leptospira transmission is favoured by various factors such as change in climatic conditions, urbanization, encroachment of wildlife inhabitation, import/export of animals, increase in adventure travel, and water related recreational activities. Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.

On the Hierarchy of Saints on Altars. Visitation Records of Otto Friedrich Buchheim, the Bishop of Ljubljana (1641–1664

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Lavrič, Ana

2011-09-01

Full Text Available The visitation records of Otto Friedrich Buchheim, the Bishop of Ljubljana from 1641–1664, offer an insight into the rules governing the disposition of saintly figures in altar retables. The central place was accorded to the titular saint, while companion saints are positioned in pairs (separately for each level of the retable in such a way that those of higher rank are placed on the more distinguished gospel side, whereas those of lower rank stand on the subordinate epistle side. The priority of one saint over another was not a matter of a random choice, but of a fixed hierarchical order which was created over the course of centuries in the Litany of All Saints and also in the hymns of the officium for All Saints Day; this hierarchy, as Buchheim remarks, is "in agreement with the general feeling of the Catholic Church". Ecclesiastical art in Slovenia shows that in the Gothic period the hierarchical principle governing the disposition of saintly figures was not yet firmly fixed, but it was fully established in the late Renaissance and Baroque periods, which coincides with the period of unification of the Litany of All Saints for the entire Catholic Church. Later it started to loosen again, yet it remained in force up to the 20th century.

Claudin11 Promoter Hypermethylation Is Frequent in Malignant Melanoma of the Skin, but Uncommon in Nevus Cell Nevi

Energy Technology Data Exchange (ETDEWEB)

Walesch, Sara K.; Richter, Antje M. [Institute for Genetics, Justus-Liebig-University Giessen, D-35392 Giessen (Germany); Helmbold, Peter [Department of Dermatology, University of Heidelberg, D-69120 Heidelberg (Germany); Dammann, Reinhard H., E-mail: reinhard.dammann@gen.bio.uni-giessen.de [Institute for Genetics, Justus-Liebig-University Giessen, D-35392 Giessen (Germany)

2015-07-07

Epigenetic inactivation of tumor-related genes is an important characteristic in the pathology of human cancers, including melanomagenesis. We analyzed the epigenetic inactivation of Claudin 11 (CLDN11) in malignant melanoma (MM) of the skin, including six melanoma cell lines, 39 primary melanoma, 41 metastases of MM and 52 nevus cell nevi (NCN). CLDN11 promoter hypermethylation was found in 19 out of 39 (49%) of the primary MM and in 21 out of 41 (51%) of the MM metastases, but only in eight out of 52 (15%) of NCN (p = 0.001 and p = 0.0003, respectively). Moreover, a significant increase in the methylation level of CLDN11 from primary melanomas to MM metastases was revealed (p = 0.003). Methylation of CLDN11 was significantly more frequent in skin metastases (79%) compared to brain metastases (31%; p = 0.007). CLDN11 methylation was also found in five out of six MM cell lines (83%) and its promoter hypermethylation correlated with a reduced expression. Treatment of MM cell lines with a DNA methylation inhibitor reactivated CLDN11 transcription by its promoter demethylation. In summary, CLDN11 proved to be an epigenetically inactivated tumor related gene in melanomagenesis, and analysis of CLDN11 methylation level represents a potential tool for assisting in the discrimination between malignant melanoma and nevus cell nevi.

AN ORTHODOX THINKER AND A ROMANIAN HEART: THE SAINT HIERARCH ANTHIM

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Henrieta Anişoara ŞERBAN

2016-10-01

Full Text Available 2016 is an anniversary year, dedicated to the Saint Hierarch Anthim, a multi-faced personality of Georgian origin, but with a Romanian accomplished life. He was a true Orthodox believer, a Hierarch of our Orthodox Church in Wallachia and a deep thinker, who lived through the teachings of the faith. At the same time, he was a good manager and a philanthropist, a scholar, a polyglot, a calligrapher, a typographer, a Church architect, an orator turned writer, a painter and a sculptor. His great homiletic work entitled Didahiile sends to Didache, the oldest post-Bible Christian text, famous at Constantinople, known also as The Teachings of the Twelve Apostles (The Teachings of the Lord to the Gentiles (or Nations by the Twelve Apostles. The study approaches and develops these dimensions of the personality and of the thought of the Saint Hierarch Anthim, in order to emphasize both his life and his work as an esteemed symbol of the Orthodox faith.

Isolation and characterization of viable Toxoplasma gondii isolates revealed possible high frequency of mixed infection in feral cats ( Felis domesticus) from St Kitts, West Indies.

Science.gov (United States)

Dubey, J P; Moura, L; Majumdar, D; Sundar, N; Velmurugan, G V; Kwok, O C H; Kelly, P; Krecek, R C; Su, C

2009-05-01

Cats are essential in the epidemiology of Toxoplasma gondii because they are the only hosts that can excrete the environmentally resistant oocysts in nature. Samples of serum, feces, and tissues from feral cats from St Kitts, West Indies were examined for T. gondii infection. Antibodies to T. gondii were assayed by the modified agglutination test, and found in 71 of 96 (73.9%) of cats with titres of 1:10 in six, 1: 20 in six,1:40 in seven,1: 80 in three, 1: 160 in 10, 1:320 in 13, 1:640 in nine, and 1:1,280 or higher in 17. Tissues of 10 cats were bio-assayed in mice. Toxoplasma gondii was isolated from tissues of 7 cats; from hearts of 6, from tongue of 5, and brains of 3 cats. All 7 isolates were avirulent for mice. Toxoplasma gondii oocysts were not found in the feces of 51 cats. Genotyping of these 7 T. gondii isolates by 10 multi-locus PCR-RFLP markers, including SAG1, SAG2, SAG3, BTUB, GRA6, c22-8, c29-2, L358, PK1, and an apicoplast marker, Apico, revealed 4 genotypes, including clonal Type II, Type III and 2 unique genotypes. Five of the 7 cats had infection with 2 genotypes, indicating high frequency of mixed infection in the cat population on the St Kitts island.

The Forging of a White Gay Aesthetic at the Saint, 1980–84

Directory of Open Access Journals (Sweden)

Tim Lawrence

2011-06-01

Full Text Available Based on original interviews with key protagonists and documentary research, the article examines the way in which the DJs who worked at the Saint forged a white gay aesthetic across the first half of the 1980s. A private party located in the East Village, New York, the Saint attracted a privileged white male crowd, and this group's position within the emerging culture of neoliberalism, along with the deepening impact of the AIDS epidemic, encouraged its spinners to sever their ties with sounds that were associated with blackness. However, if Saint DJs rejected a high proportion of records that were being released by New York's independents, and also snubbed Chicago house when it broke in 1985, their forging of an aesthetic that emphasised seamless transitions, often between records that contained similar sonic qualities, preempted the style of mixing that would be popularised in house music culture.

Profiling of ABC transporters ABCB5, ABCF2 and nestin-positive stem cells in nevi, in situ and invasive melanoma.

Science.gov (United States)

Setia, Namrata; Abbas, Ossama; Sousa, Yessica; Garb, Jane L; Mahalingam, Meera

2012-08-01

Distinct ABCB5 forms and ABCF2, members of the ATP-binding cassette (ABC) superfamily of transporters, are normally expressed in various tissues and cells, and enhanced expression of both has been demonstrated in select cancers. In melanoma cell lines, gene expression profiling of ABC transporters has revealed enhanced expression of melanocyte-specific ABCB5 and ABCF2 proteins. Given this, our primary aim was to ascertain immunohistochemical expression of the ABC transporters ABCB5 and ABCF2 and, the stem cell marker, nestin in a spectrum of benign and malignant nevomelanocytic proliferations, including nevi (n=30), in situ (n=31) and invasive (n=24) primary cutaneous melanomas to assess their role in the stepwise development of malignancy. In addition, their expression was compared with established melanoma prognosticators to ascertain their utility as independent prognosticators. A semiquantitative scoring system was utilized by deriving a cumulative score (based on percentage positivity cells and intensity of expression) and statistical analyses was carried out using analysis of variance with linear contrasts. Mean cumulative score in nevi, in situ and invasive melanoma were as follows: 3.8, 4.4 and 5.3 for ABCB5, respectively (P1, after controlling for the presence of ulceration and mitotic activity, the expression of both proteins did not significantly correlate with known melanoma prognosticators. The gradual increase in the expression of ABCB5 from benign nevus to in situ to invasive melanoma suggests that it plays a role in melanomagenesis. On the basis of our findings, a prospective study with follow-up data is required to ascertain the utility of ABCB5 as a therapeutic target.

[On the medical and publishing activities of the community of Saint Eugene].

Science.gov (United States)

2012-01-01

The article deals with the role the physicians played in organization and functioning of the Community of Saint Eugene in St. Petersburg in 1882-1918. The typography production of the Community being of interest for history of medicine is examined.

Survey of vector-borne agents in feral cats and first report of Babesia gibsoni in cats on St Kitts, West Indies.

Science.gov (United States)

Kelly, Patrick John; Köster, Liza; Li, Jing; Zhang, Jilei; Huang, Ke; Branford, Gillian Carmichael; Marchi, Silvia; Vandenplas, Michel; Wang, Chengming

2017-11-13

As there is little data on vector-borne diseases of cats in the Caribbean region and even around the world, we tested feral cats from St Kitts by PCR to detect infections with Babesia, Ehrlichia and spotted fever group Rickettsia (SFGR) and surveyed them for antibodies to Rickettsia rickettsii and Ehrlichia canis. Whole blood was collected from apparently healthy feral cats during spay/ neuter campaigns on St Kitts in 2011 (N = 68) and 2014 (N = 52). Sera from the 52 cats from 2014 were used to detect antibodies to Ehrlichia canis and Rickettsia rickettsii using indirect fluorescent antibody tests and DNA extracted from whole blood of a total of 119 cats (68 from 2011, and 51 from 2014) was used for PCRs for Babesia, Ehrlichia and Rickettsia. We could not amplify DNA of SFG Rickettsia in any of the samples but found DNA of E. canis in 5% (6/119), Babesia vogeli in 13% (15/119), Babesia gibsoni in 4% (5/119), mixed infections with B. gibsoni and B. vogeli in 3% (3/119), and a poorly characterized Babesia sp. in 1% (1/119). Overall, 10% of the 52 cats we tested by IFA for E. canis were positive while 42% we tested by indirect fluorescent antibody (IFA) for R. rickettsii antigens were positive. Our study provides the first evidence that cats can be infected with B. gibsoni and also indicates that cats in the Caribbean may be commonly exposed to other vector-borne agents including SFGR, E. canis and B. vogeli. Animal health workers should be alerted to the possibility of clinical infections in their patients while public health workers should be alerted to the possibility that zoonotic SFGR are likely circulating in the region.

New observations on the miniature of the vision of Saint Gregory of Nazianzus in Paris. GR. 510

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Gavrilović Zaga

2007-01-01

Full Text Available The article deals with the iconography of the illustration of the Second Paschal Homily of St. Gregory of Nazianzus on fol. 285r of the Paris manuscript. It questions the identity of the woman saint represented on the right of St. Paraskeve in the lower register of the scene. Unlike that above St. Paraskeve, the inscription identifying this second woman saint is fragmentary and difficult to read, but it has been widely accepted that she is Saint Helena, mother of the Emperor Constantine the Great. On the basis of two other representations of Helena in the same manuscript and of the style of the inscription accompanying them, as well as taking into account the importance of the theological meaning expounded by St. Gregory in his oration, it is suggested that the second woman saint may be St. Kyriake.

De Manet a Yves Saint-Laurent: uma análise semiótica

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Christiane Paula Godinho Santarelli

2008-09-01

Full Text Available A proposta deste artigo é fazer uma análise semiótica, com base na teoria greimasiana, da pintura original de Manet Le déjeuner sur l’herbe e de sua recriação para o anúncio da marca Yves Saint-Laurent. Os aspectos analisados nos dois “textos” são: os sistemas de valores, a estrutura narrativa, a estrutura de poder, os objetos de valor e a semântica profunda. A comparação dos dois discursos tem como objetivo atentar para as contradições no suposto discurso libertador da publicidade de Yves Saint-Laurent, que pode estar presente na publicidade de outras marcas. Palavras-chave: Publicidade; semiótica; arte; moda. ABSTRACT The purpose of this article is to offer a semiotical analysis of the original painting of Manet Le déjeuner sur l’herbe and of its recreation in an advertisement for the brand Yves Saint-Laurent. The aspects analyzed in the two “texts” are: the systems of enclosed values, the narrative structure, the power structure, the objects of value and deep semantics. The comparison between the two forms of speech aims to highlight the contradictions in the alleged liberating speech of the Yves Saint-Laurent advertisement, which may be present in advertising pieces from other brands. Keywords: Advertising; semiotics; art; fashion.

Geologic map of Saint Lawrence Island, Alaska

Science.gov (United States)

Patton, William W.; Wilson, Frederic H.; Taylor, Theresa A.

2011-01-01

Saint Lawrence Island is located in the northern Bering Sea, 190 km southwest of the tip of the Seward Peninsula, Alaska, and 75 km southeast of the Chukotsk Peninsula, Russia (see index map, map sheet). It lies on a broad, shallow-water continental shelf that extends from western Alaska to northeastern Russia. The island is situated on a northwest-trending structural uplift exposing rocks as old as Paleozoic above sea level. The submerged shelf between the Seward Peninsula and Saint Lawrence Island is covered mainly with Cenozoic deposits (Dundo and Egiazarov, 1982). Northeast of the island, the shelf is underlain by a large structural depression, the Norton Basin, which contains as much as 6.5 km of Cenozoic strata (Grim and McManus, 1970; Fisher and others, 1982). Sparse test-well data indicate that the Cenozoic strata are underlain by Paleozoic and Proterozoic rocks, similar to those exposed on the Seward Peninsula (Turner and others, 1983). Saint Lawrence Island is 160 km long in an east-west direction and from 15 km to 55 km wide in a north-south direction. The east end of the island consists largely of a wave-cut platform, which has been elevated as much as 30 m above sea level. Isolated upland areas composed largely of granitic plutons rise as much as 550 m above the wave-cut platform. The central part of the island is dominated by the Kookooligit Mountains, a large Quaternary shield volcano that extends over an area of 850 km2 and rises to an elevation of 630 m. The west end of the island is composed of the Poovoot Range, a group of barren, rubble-covered hills as high as 450 m that extend from Boxer Bay on the southwest coast to Taphook Mountain on the north coast. The Poovoot Range is flanked on the southeast by the Putgut Plateau, a nearly flat, lake-dotted plain that stands 30?60 m above sea level. The west end of the island is marked by uplands underlain by the Sevuokuk pluton (unit Kg), a long narrow granite body that extends from Gambell on the

MARKETING STRATEGY FOR THE FINNISH TOURIST COMPANY BASED ON SAINT PETERSBURG MARKET RESEARCH

OpenAIRE

Miroshnichenko, Julia

2014-01-01

The goal of this thesis is to get a marketing strategy for proposed tourist business through the field-work marketing research. The purpose of this marketing research was to investigate the attitudes of Russian tourists in Saint Pe-tersburg towards Finland as a destination. The research examines the respondents’ own evaluation of the Finnish tourism possibilities, as well as the expert evaluation (made by the professionals of tourist agencies in Saint Petersburg) of the Finnish tourist ma...

THE APOSTLE PAUL: THEOLOGIAN-MISSIONARY AND PASTOR-THEOLOGIAN. TOWARDS A DEEPER UNDERSTANDING OF SAINT PAUL

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Eckhart Schnabel

2013-04-01

Full Text Available This Article is an attempt to shed light on a few texts of the acts of the Apostles and of the epistles which are viewed as sources documenting the life and activity of Saint Paul. The author attempts to settle a number of questions regarding the authenticity of sources illustrating the life of Saint Paul. Similar questions are often raised by those who write and publish guides and textbooks for the teaching of the Pauline corpus. The author agrees with the overwhelming positive judgment of the academic world regarding the authenticity of the pastoral epistles, but at the same time he notes a number of objections to their authenticity proposed by the same forum: inconsistencies within the vocabulary of the texts themselves, their linguistic style, and their theological argumentation. The author concludes that these objections are inconclusive and the features enumerated by those who object constitute in reality only minor exceptions, inconsequential when taking into account the entire Pauline corpus. The author also examines the authenticity and historical accuracy of the account of the life of Saint Paul as given in the Acts of the Apostles. A few Biblicists claim that the account in Acts is merely legendary and is to be regarded as a type of early Christian folklore. The author disagrees with this opinion, backing up his position with the evidence that both the Acts of the Apostles and the Pastoral Epistles agree in historical detail and background. The author concludes with a further consideration regarding the correct method guiding biblical research on Saint Paul. He opines that such research must view the biblical texts in a correct historical perspective

A restoration and conservation project of the “Saint Dominic” Monastery in Soriano Calabro, Italy

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Nazzareno Davolos

2008-04-01

Full Text Available The article is extracted from the Master Thesis about Restoration of the Monuments at “La Sapienza”, University of the Studies of Rome. The Monastery was one of the most important of the Dominican Order in Europe. The building dates back to year 1510, it broke down almost completely in the earthquake of year 1659. It was rebuilt following the architect B. Presti’s project. At the present time the “Saint Domenic” Monastery largely seems a ruin, mainly as a consequence of the cat- N. Davolos - A restoration and conservation project of the ÒSaint DominicÓ Monastery... 185 astrophic earthquake in 1783. However, with the new look that has acquired, it still preserves an extraordinary charm that continues to astonish. The project followed the trend of the critical and conservative restoration with the safeguard of the artistic and figurative data of the “Saint Domenic” Monastery which has been analysed through an accurate historical-critical work. The idea is to preserve and transmit to the future generations the “Saint Domenic” monument in his authenticity, in its formal and material consistence, with the marks of the passing of time. The abstracts reports only the most important aspects which are representative of the project. Besides the historical analysis, laboratory examination have been executed on the material used in the construction of the ancient facade through the observation of thin sections by optic microscope and with the realization of spectrum of X-ray diffraction, in order to know the nature and composition, the state of preservation and the kinds of deterioration to support an appropriate intervention of restoration.

Latter-Day Saint Women and Leadership: The Influence of Their Religious Worldview

Science.gov (United States)

Madsen, Susan R.

2016-01-01

The article examines theories, assumptions, concepts, experiences, and practices from the Latter-day Saints' (LDS, or the Mormons) religious worldview to expand existing theoretical constructs and implications of leadership development and education for women. The article elucidates LDS doctrine and culture regarding women and provides specific…

Molecular characterization of canine parvovirus and canine enteric coronavirus in diarrheic dogs on the island of St. Kitts: First report from the Caribbean region.

Science.gov (United States)

Navarro, Ryan; Nair, Rajeev; Peda, Andrea; Aung, Meiji Soe; Ashwinie, G S; Gallagher, Christa A; Malik, Yashpal S; Kobayashi, Nobumichi; Ghosh, Souvik

2017-08-15

Although canine parvovirus (CPV) and canine enteric coronavirus (CCoV) are important enteric pathogens of dogs and have been studied extensively in different parts of the world, there are no reports on these viruses from the Caribbean region. During 2015-2016, a total of 104 diarrheic fecal samples were collected from puppies and adult dogs, with or without hemorrhagic gastroenteritis, on the Caribbean island of St. Kitts (KNA). By PCR, 25 (24%, n=104) samples tested positive for CPV. Based on analysis of the complete deduced VP2 amino acid sequences, 20 of the KNA CPV strains were assigned to new CPV-2a (also designated as CPV-2a-297A). On the other hand, the VP2 genes of the remaining 5 strains were partially characterized, or could not be sequenced. New CPV-2a was the predominant CPV variant in St. Kitts, contrasting the molecular epidemiology of CPV variants reported in most studies from nearby North and South American countries. By RT-PCR, CCoVs were detected in 5 samples (4.8%, n=104). Based on analysis of partial M-protein gene, the KNA CCoV strains were assigned to CCoV-I genotype, and were closely related to CCoV-I strains from Brazil. To our knowledge, this is the first report on detection and genetic diversity of CPV and CCoV in dogs from the Caribbean region, and underscores the importance of similar studies in the other Caribbean islands. Copyright © 2017 Elsevier B.V. All rights reserved.

Public meeting of September 13, 2005 at Saint-Dizier; Reunion publique du 13 septembre 2005 a Saint-Dizier

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

The law from December 30, 1991, precisely defines 3 axes of researches for the management of high level and long-lived radioactive wastes: separation/transmutation, surface storage and underground disposal. A global evaluation report about these researches is to be supplied in 2006 by the French government to the Parliament. A first synthesis of the knowledge gained after 14 years of research has led the national commission of the public debate (CNDP) to organize a national debate about the general options of management of high-level and long-lived radioactive wastes before the 2006 date line. The debate comprises 4 public hearings (September 2005: Bar-le-Duc, Saint-Dizier, Pont-du-Gard, Cherbourg), 12 round-tables (October and November 2005: Paris, Joinville, Caen, Nancy, Marseille), a synthesis meeting (December 2005, Dunkerque) and a closing meeting (January 2006, Lyon). This document is the synthesis of the debates of the second public hearing at Saint-Dizier. This meeting gathers representatives of the different actors of the nuclear industry, ministers, public authorities, non governmental organizations who argue the questions asked by peoples from the audience. The topics concern the safety aspects of waste facilities, in particular according to the studies carried out at the Bure site, the different categories of wastes and the future wastes that will be generated by the dismantling of nuclear facilities etc. (J.S.)

L’église Saint-Michel de Lille : chronologie d’un chantier

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Catherine Guillot

2012-04-01

Full Text Available Après le démantèlement des fortifications de Lille en 1858, un nouveau quartier est aménagé au sud de la ville, dont un des équipements importants est l’église Saint-Michel, construite entre 1868 et 1874 par l’architecte Alfred Coisel. Très bien documenté, son chantier dévoile un mobilier et un décor exemplaire par son homogénéité et par la place accordée à la peinture murale. Cette étude met en évidence, outre le rôle du peintre Alphonse Colas, des artistes méconnus comme Albéric Duyver et Marie Carin. L’iconographie, qui révèle un des plus importants cycles consacrés à l’archange saint Michel, est également extrêmement caractéristique de son temps.After the demolition of the fortifications at Lille, in 1858, a new quarter developed to the south of the city. One of the important features of this new neighbourhood was the Saint-Michel church, built between 1868 and 1874 to the designs of the architect Alfred Coisel. The building of this church is exceptionally well documented and reveals church furnishings and decoration of an exemplary nature in terms of homogeneity and the special place given over to mural paintings. This study underlines the role of the painter Alphonse Colas, but also the contribution of other, less well known artists such as Albéric Duyver and Marie Carin. The iconographical theme is one of the most important cycles of its time devoted to the archangel Saint Michel, and is highly characteristic of the period.

Saint John lateral pipeline project: comprehensive study report

International Nuclear Information System (INIS)

1999-02-01

A descripion is given of the results of an environmental impact assessment of the construction of a natural gas pipeline that will bring gas from Maritimes and Northeast Pipeline Management Ltd.'s (M and NP) main transmission pipeline to clients in Lake Utopia and Saint John, NB. It will be 110 km long, and the Saint John lateral will join the mainline approximately 2 km south of Big Kedron Lake, NB. Various institutional, industrial, commercial and residential clients will be able to access the pipeline in the future, and it is intended to be capable of future expansion for markets along its route and for markets that become economically feasible in the future. A matrix was developed that relates environmental resources to Environmental Components of Concern (ECCs), and to the rationale for exclusion/inclusion of the ECC as a Valued Environmental Component (VECs). The positive benefits of the pipeline to clients in the Saint John area include: reduced dependence on foreign oil, fuel switching and price competition, lower air emission pollution, increased energy efficiency, and a source of energy that is secure and reliable. VECs were selected based on: concerns of various stakeholders including the public, community groups, scientific parties, Aboriginal groups, government officials and agencies, relevant regulations; relevant literature; and past evaluation experiences, including future developments of the proposed study area. Further selection of the VECs required an examination of the issues picked out via scoping to determine the ways in which the overall project could affect the ECCs, and included construction, operation, decommissioning/abandonment, malfunctions and accidents of the pipeline. The phases of the project as they impacted residually and cumulatively on the VECs were evaluated, and impacts on Valued Socio-Economic Components (VSCs) were assessed also. The mitigation efforts taken will minimize the potential effects of the project on VECs and VSCs

IAEA Operational Safety Team Reviews Saint-Alban Nuclear Power Plant, France

International Nuclear Information System (INIS)

2010-01-01

Full text: An international team of nuclear installation safety experts, led by the International Atomic Energy Agency (IAEA), has reviewed safety practices at France's Saint-Alban Nuclear Power Plant (NPP) and has highlighted a set of strong practices as well as a series of recommendations to reinforce them. The IAEA assembled the team at the request of the Government of France to conduct an Operational Safety Review (OSART) of the Saint-Alban NPP. Under the leadership of the IAEA's Division of Nuclear Installation Safety in Vienna, the OSART team performed an in-depth operational safety review from 20 September to 6 October 2010. The team was made up of experts from Belgium, Canada, the Czech Republic, Germany, Lithuania, the Netherlands, Slovakia, Sweden and the USA. An OSART mission is designed to review programmes and activities essential to operational safety. It is not a regulatory inspection, nor is it a design review or a substitute for an exhaustive assessment of the plant's overall safety status. The team at Saint-Alban conducted an in-depth review of the aspects essential to the safe operation of the NPP, which largely are under the control of the site management. The conclusions of the review are based on the IAEA's Safety Standards and proven good international practices. The review covered the areas of Management, Organization and Administration; Training and Qualification; Operations; Maintenance; Technical Support; Operating Experience; Radiation Protection; Chemistry; and Emergency Planning and Preparedness. The OSART team has identified good plant practices, which will be shared with the rest of the nuclear industry for consideration of their application. Examples include: A safety guideline for outages; The use of remote video surveillance of fuel inspection and handling activities; A motivational tool for plant staff regarding the benefits of operating experience and associated corrective actions; and Use of a sophisticated key control system

Calculation of Void in the Fort Saint Vrain Material

Energy Technology Data Exchange (ETDEWEB)

Potter, David Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Taylor, Craig Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Coons, James Elmer [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2017-05-11

The percent void of the Fort Saint Vrain (FSV) material is estimated to be 21.1% based on the volume of the gap at the top of the drums, the volume of the coolant channels in the FSV fuel element, and the volume of the fuel handling channel in the FSV fuel element.

A School-Based Enterprise: The Saint Pauls, North Carolina Experience.

Science.gov (United States)

Paquin, Thomas F.

1991-01-01

The superintendent of Saint Pauls Schools describes how educators, community leaders, businesspersons, and high school students worked together to develop the Way Off Broadway Deli, a successful school-based enterprise providing experiential education in entrepreneurship and small business management, as well as student employment and local…

The “Enemy” of the Saint in the Vita Fulgentii

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Isabella D'Auria

2015-06-01

Full Text Available This paper aims to analyze the traits that characterize the “enemy” of the saint in the Vita Fulgentii. The work tells in twenty-nine chapters the life of the bishop of Ruspe Fulgentius, troubled by exile and persecutions both in the monastic phase and in the episcopal one, in the context of the vandalic invasion in Africa between 5th and 6th century. The “enemy”, that identifies, in the most cases, with the invader of arian faith, presents a stereotyped nature, summarizing the tipical characteristics of barbarian and the ones specific to the heterodox. In order to achieve the goal of the reader’s moral edification, the text presents antithetical models, the saint ant his opposer, and all the account revolves around this dialectic; so it is worthy of interest to pick out the elements that define, throught a relationship of opposition, the collective identities, that in this text are represented by Catholics invaded and by barbarian and heretic invaders.

HIV Viral Load Trends in Six Eastern Caribbean Countries Utilizing a Regional Laboratory Referral Service: Implications for Treatment as Prevention.

Science.gov (United States)

Landis, R Clive; Carmichael-Simmons, Kelly; Hambleton, Ian R; Best, Anton

2015-01-01

Since 2009, seven countries in the Organization of Eastern Caribbean States (OECS), Antigua & Barbuda, Dominica, Grenada, Montserrat, St. Kitts & Nevis, Saint Lucia, and St. Vincent & the Grenadines, have been utilizing a laboratory referral service for HIV-1 viral load (VL) offered by The Ladymeade Reference Unit (LRU) Laboratory, Barbados. The objective of this study was to evaluate 5 year VL trends in the six larger OECS countries participating in this regional referral service. Blood samples were collected in source countries and transported to Barbados as frozen plasma according to a standardized protocol. Plasma specimens were amplified by RT PCR on a Roche TaqMan 48 analyser (Roche Diagnostics, Panama City, Panama). VL was considered optimally suppressed below a threshold level of < 200 HIV-1 copies/mL of blood. The same threshold was used as a binary indicator in an analysis of the secular change in VL suppression. Montserrat was excluded due to insufficient number of samples. A steady rise in VL referrals from OECS countries was recorded, rising from 312 samples in 2009 to 1,060 samples in 2013. A total of 3,543 samples were tested, with a sample rejection rate (9.2%) mostly due to breaks in the cold chain. Aggregate VL data showed the odds of VL suppression in the Eastern Caribbean improved by 66% for each additional year after 2009 (Odds Ratio 1.66 [95% CI 1.46 to 1.88]; p<0.001). We demonstrate the feasibility of establishing a regional laboratory referral service for HIV VL monitoring in the Eastern Caribbean. Aggregate VL trends showed a significant year-on-year improvement in VL suppression, implying public health benefits through treatment as prevention in the OECS. VL provides a powerful monitoring & evaluation tool for strengthening HIV programs at country level among the small island states participating in this regional referral network.

HIV Viral Load Trends in Six Eastern Caribbean Countries Utilizing a Regional Laboratory Referral Service: Implications for Treatment as Prevention.

Directory of Open Access Journals (Sweden)

R Clive Landis

Full Text Available Since 2009, seven countries in the Organization of Eastern Caribbean States (OECS, Antigua & Barbuda, Dominica, Grenada, Montserrat, St. Kitts & Nevis, Saint Lucia, and St. Vincent & the Grenadines, have been utilizing a laboratory referral service for HIV-1 viral load (VL offered by The Ladymeade Reference Unit (LRU Laboratory, Barbados. The objective of this study was to evaluate 5 year VL trends in the six larger OECS countries participating in this regional referral service.Blood samples were collected in source countries and transported to Barbados as frozen plasma according to a standardized protocol. Plasma specimens were amplified by RT PCR on a Roche TaqMan 48 analyser (Roche Diagnostics, Panama City, Panama. VL was considered optimally suppressed below a threshold level of < 200 HIV-1 copies/mL of blood. The same threshold was used as a binary indicator in an analysis of the secular change in VL suppression. Montserrat was excluded due to insufficient number of samples.A steady rise in VL referrals from OECS countries was recorded, rising from 312 samples in 2009 to 1,060 samples in 2013. A total of 3,543 samples were tested, with a sample rejection rate (9.2% mostly due to breaks in the cold chain. Aggregate VL data showed the odds of VL suppression in the Eastern Caribbean improved by 66% for each additional year after 2009 (Odds Ratio 1.66 [95% CI 1.46 to 1.88]; p<0.001.We demonstrate the feasibility of establishing a regional laboratory referral service for HIV VL monitoring in the Eastern Caribbean. Aggregate VL trends showed a significant year-on-year improvement in VL suppression, implying public health benefits through treatment as prevention in the OECS. VL provides a powerful monitoring & evaluation tool for strengthening HIV programs at country level among the small island states participating in this regional referral network.

Ecole d’été de probabilités de Saint-Flour XXVIII

CERN Document Server

2000-01-01

This volume contains lectures given at the Saint-Flour Summer School of Probability Theory during 17th Aug. - 3rd Sept. 1998. The contents of the three courses are the following: - Continuous martingales on differential manifolds. - Topics in non-parametric statistics. - Free probability theory. The reader is expected to have a graduate level in probability theory and statistics. This book is of interest to PhD students in probability and statistics or operators theory as well as for researchers in all these fields. The series of lecture notes from the Saint-Flour Probability Summer School can be considered as an encyclopedia of probability theory and related fields.

Semi-automated non-invasive diagnostics method for melanoma differentiation from nevi and pigmented basal cell carcinomas

Science.gov (United States)

Lihacova, I.; Bolocko, K.; Lihachev, A.

2017-12-01

The incidence of skin cancer is still increasing mostly in in industrialized countries with light- skinned people. Late tumour detection is the main reason of the high mortality associated with skin cancer. The accessibility of early diagnostics of skin cancer in Latvia is limited by several factors, such as high cost of dermatology services, long queues on state funded oncologist examinations, as well as inaccessibility of oncologists in the countryside regions - this is an actual clinical problem. The new strategies and guidelines for skin cancer early detection and post-surgical follow-up intend to realize the full body examination (FBE) by primary care physicians (general practitioners, interns) in combination with classical dermoscopy. To implement this approach, a semi- automated method was established. Developed software analyses the combination of 3 optical density images at 540 nm, 650 nm, and 950 nm from pigmented skin malformations and classifies them into three groups- nevi, pigmented basal cell carcinoma or melanoma.

On the Life and Deeds of San Precario, Patron Saint of Precarious Workers and Lives

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Marcello Tarì

2005-01-01

Full Text Available Noi siamo la generazione post-socialista, la generazione del dopo guerra fredda, della fine delle burocrazie verticali e del controllo sull'informazione. Siamo un movimento globale e neuropeo, che porta avanti la rivoluzione democratica scaturita dal Sessantotto mondiale e lotta contro la distopia neoliberista oggi al culmine. Siamo ecoattivisti e mediattivisti, siamo i libertari della Rete e i metroradicali dello spazio urbano, siamo le mutazioni transgender del femminismo globale, siamo gli hacker del terribile reale. Siamo gli agitatori del precariato e gli insorti del cognitariato. Siamo anarcosindacalisti e postsocialisti. Siamo tutti migranti alla ricerca di una vita migliore. E non ci iconosciamo in voi, stratificazioni tetre e tetragone di ceti politici sconfitti già nel XX secolo. Non ci riconosciamo nella sinistra italyana.Manifesto Bio/Pop del Precariato Metroradicale, 20042004 has marked the beginning of the spreading "cult" of San Precario, Patron Saint of precarious, casual, sessional, temporary, flexible and fractional workers. The Saint appears in public spaces in occasion of rallies, marches, interventions and demonstrations, and its popularity has lead to development of a precise and colorful iconography, hagiography and rituals. This popularity conversely is also the sign of the gravity of the issue of precarity in Italy and Europe .San Precario epitomises current Italian activist practices. These practices, although specifically Italian, intersect with similar realities in Europe and are based on mythopoetic narratives and actions and mediatic embodiments. This paper analysis a variety of texts produced around San Precario, from posters, saint cards, product cards, videos, "official" narratives, personal accounts, relating them to the political debate surrounding precarity.

Bunker culturel : la régénération du patrimoine militaire urbain à Saint-Nazaire

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Renzo Lecardane

2011-06-01

Full Text Available Au cours des deux dernières décennies Saint-Nazaire a relancé son développement sans se référer nécessairement aux modèles des métropoles européennes. Concentrées autour de la zone portuaire, près de la base sous-marine allemande, les nouvelles opérations urbaines ont contribué à définir un important projet touristique et culturel. La spécificité symbolique et la valorisation du patrimoine militaire ont permis à Saint-Nazaire de montrer que l’identité d’une ville pouvait activer sa croissance.Over the last two decades, the port city of Saint-Nazaire has encouraged urban redevelopment without necessarily following the models suggested by other European cities. An important cultural and tourist centre has been developed around the port zone, close to the German submarine base dating from the Second World War. The symbolic specificity and the interpretation of this military heritage have shown, at Saint-Nazaire, how a town's special identity can foster growth.

New optical museum at Saint-Petersburg for education and training

Science.gov (United States)

Vasil'ev, V. N.; Stafeef, S. K.; Tomilin, M. G.

2009-06-01

Nowadays the educational problem of teaching optics and photonics is to attract the young generation to the wonderful and magic world of light, optical science, technology and systems. The main issue is to explain that in the course of last several hundred years optics has been representing the most clear world view for humanity. In fact, the optics itself is a multidisciplinary complex of independent scientific directions, and, moreover, it has always been a generator of new fields of knowledge. Besides, optics and photonics are the fields within which the most fundamental problems of today's reality are to be resolved. It is absolutely necessary to encourage our scholars in getting optics and photonics education as an alternative physical basis to gaining solely computer knowledge. The main obstacle is the poor connection between program of optical education and the real optical researches, disintegration of different branches of the optical science, the demographic situation, some problems with teaching mathematics and physics at schools, and the collision between traditional educational methods and the mentality of the new generation. In Russia the Saint-Petersburg State University of Information Technologies, Mechanics and Optics offers partial solution to these problems: the organization of a real place for interactive optical science in a form of a new museum of optics, intended for education and training, seems to be the most effective way. This was the main reason for establishing such a museum in Saint-Petersburg at the end of 2008.

PREFACE: 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures

Science.gov (United States)

2014-09-01

Dear Colleagues, 1st International School and Conference "Saint Petersburg OPEN 2014" on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 25 - 27, 2014 at St. Petersburg Academic University - Nanotechnology Research and Education Centre of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were: Mikhail Glazov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir Dubrovskii (Saint Petersburg Academic University RAS, Russia) Alexey Kavokin (University of Southampton, United Kingdom and St. Petersburg State University, Russia) Vladimir Korenev (Ioffe Physico-Technical Institute RAS, Russia) Sergey Kukushkin (Institute of Problems of Mechanical Engineering RAS, Russia) Nikita Pikhtin (Ioffe Physico-Technical Institute RAS, Russia and "Elfolum" Ltd., Russia) Dmitry Firsov (Saint Petersburg State Polytechnical University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. Sufficiently large number of participants with more than 160 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year's School and Conference is supported by SPIE (The International Society for Optics and Photonics), OSA (The Optical Society), St. Petersburg State Polytechnical University and by Skolkovo Foundation. It is a continuation of the annual schools and

Developing Semi-Analytical solutions for Saint-Venant Equations in the Uniform Flow Region

Directory of Open Access Journals (Sweden)

M.M. Heidari

2016-09-01

Full Text Available Introduction: Unsteady flow in irrigation systems is the result of operations in response to changes in water demand that affect the hydraulic performance networks. The increased hydraulic performance needed to recognize unsteady flow and quantify the factors affecting it. Unsteady flow in open channels is governed by the fully dynamic Saint Venant equation, which express the principles of conservation of mass and momentum. Unsteady flow in open channels can be classified into two types: routing and operation-type problems. In the routing problems, The Saint Venant equations are solved to get the discharge and water level in the time series. Also, they are used in the operation problem to compute the inflow at the upstream section of the channel according to the prescribed downstream flow hydrographs. The Saint Venant equation has no analytical solution and in the majority cases of such methods use numerical integration of continuity and momentum equations, and are characterized by complicated numerical procedures that are not always convenient for carrying out practical engineering calculations. Therefore, approximate methods deserve attention since they would allow the solution of dynamic problems in analytical form with enough exactness. There are effective methods for automatic controller synthesis in control theory that provide the required performance optimization. It is therefore important to get simplified models of irrigation canals for control design. It would be even more interesting to have linear models that explicitly depend on physical parameters. Such models would allow one to, handle the dynamics of the system with fewer parameters, understand the impact of physical parameters on the dynamics, and facilitate the development a systematic design method. Many analytical models have been proposed in the literature, Most of them have been obtained in the frequency domain by applying Laplace transform to linearized Saint

The eleventh CRL-Salmonella workshop, 9 May 2006, Saint Malo, France

NARCIS (Netherlands)

Mooijman KA; MGB

2006-01-01

De elfde workshop georganiseerd door het Communautair Referentie Laboratorium voor Salmonella (CRL-Salmonella) werd gehouden op 9 mei 2006 in Saint Malo, Frankrijk. Deelnemers waren vertegenwoordigers van de nationale Referentie Laboratoria voor Salmonella (NRLs-Salmonella) van de lidstaten van de

Diet of the oilfish Ruvettus pretiosus (Perciformes: Gempylidae in the Saint Peter and Saint Paul archipelago, Brazil

Directory of Open Access Journals (Sweden)

Danielle de Lima Viana

2012-06-01

Full Text Available Feeding aspects of the oilfish, Ruvettus pretiosus, were studied based on 360 stomachs of both male and female specimens caught off the Saint Peter and Saint Paul Archipelago. The total length of the specimens ranged from 52.4 cm to 189.0 cm. Of the 360 stomachs examined, 135 presented some food and 225 were empty. Thirty-four taxa were identified, represented by 16 fish, 17 cephalopods and 1 crustacean. The stabilization of the food items richness was attained at 35 food items and 104 stomachs, approximately. A remarkable predation upon the flying fish Cheilopogon cyanopterus was observed around SPSPA, directly related to the main reproductive period of this species in the area. The oilfish's food spectrum shows that the species feeds on a wide vertical range in the water column, catching prey items at the surface or in shallow waters, as well as epi-mesopelagic fish, in addition to mesopelagic cephalopods.Aspectos alimentares do peixe-prego, Ruvettus pretiosus, foram estudados com base nos estômagos de 360 espécimes, de ambos os sexos, capturados nos arredores do Arquipélago de São Pedro e São Paulo. Todos os exemplares foram capturados com linha de mão. O comprimento total dos exemplares variou de 52,4 cm a 189,0 cm. Dos 360 estômagos examinados, 135 apresentaram algum alimento e 225 estavam vazios. Trinta e quatro táxons foram identificados, representados por 16 peixes, 17 cefalópodes e um crustáceo. A estabilização da riqueza dos itens alimentares foi obtida com 35 itens e 104 estômagos. Uma predação notável sobre o peixe-voador Cheilopogon cyanopterus foi observada nas adjacências do ASPSP, diretamente relacionada com o principal período reprodutivo dessa espécie na área. O espectro alimentar do peixe-prego mostra que a espécie se alimenta em uma ampla faixa vertical na coluna d'agua, capturando desde presas de superfície ou águas rasas, a peixes epi-mesopelágicos, além de cefalópodes mesopelágicos.

History of psychosurgery at Sainte-Anne Hospital, Paris, France, through translational interactions between psychiatrists and neurosurgeons.

Science.gov (United States)

Zanello, Marc; Pallud, Johan; Baup, Nicolas; Peeters, Sophie; Turak, Baris; Krebs, Marie Odile; Oppenheim, Catherine; Gaillard, Raphael; Devaux, Bertrand

2017-09-01

Sainte-Anne Hospital is the largest psychiatric hospital in Paris. Its long and fascinating history began in the 18th century. In 1952, it was at Sainte-Anne Hospital that Jean Delay and Pierre Deniker used the first neuroleptic, chlorpromazine, to cure psychiatric patients, putting an end to the expansion of psychosurgery. The Department of Neuro-psychosurgery was created in 1941. The works of successive heads of the Neurosurgery Department at Sainte-Anne Hospital summarized the history of psychosurgery in France. Pierre Puech defined psychosurgery as the necessary cooperation between neurosurgeons and psychiatrists to treat the conditions causing psychiatric symptoms, from brain tumors to mental health disorders. He reported the results of his series of 369 cases and underlined the necessity for proper follow-up and postoperative re-education, illustrating the relative caution of French neurosurgeons concerning psychosurgery. Marcel David and his assistants tried to follow their patients closely postoperatively; this resulted in numerous publications with significant follow-up and conclusions. As early as 1955, David reported intellectual degradation 2 years after prefrontal leucotomies. Jean Talairach, a psychiatrist who eventually trained as a neurosurgeon, was the first to describe anterior capsulotomy in 1949. He operated in several hospitals outside of Paris, including the Sarthe Psychiatric Hospital and the Public Institution of Mental Health in the Lille region. He developed stereotactic surgery, notably stereo-electroencephalography, for epilepsy surgery but also to treat psychiatric patients using stereotactic lesioning with radiofrequency ablation or radioactive seeds of yttrium-90. The evolution of functional neurosurgery has been marked by the development of deep brain stimulation, in particular for obsessive-compulsive disorder, replacing the former lesional stereotactic procedures. The history of Sainte-Anne Hospital's Neurosurgery Department sheds

Un solveur HLLT pour les equations de Saint-Venant et traitement ...

African Journals Online (AJOL)

Un solveur HLLT pour les equations de Saint-Venant et traitement des ... Enfin, des applications numériques sur des cas tests sont présentées. ... the system of partial-differential equations is completed by a trivial equation for the bathymetry.

Un solveur HLLTpour les equations de Saint-vVenant et traitement ...

African Journals Online (AJOL)

Un solveur HLLTpour les equations de Saint-vVenant et traitement des ... Enfin, des applications numériques sur des cas tests sont présentées. ... the system of partial-differential equations is completed by a trivial equation for the bathymetry.

Ehrlichiosis, babesiosis, anaplasmosis and hepatozoonosis in dogs from St. Kitts, West Indies.

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Patrick J Kelly

Full Text Available BACKGROUND: Although tick-borne diseases are important causes of morbidity and mortality in dogs in tropical areas, there is little information on the agents causing these infections in the Caribbean. METHODOLOGY: We used PCRs to test blood from a cross-section of dogs on St Kitts for Ehrlichia (E. canis, Babesia (B. spp., Anaplasma (A. spp. and Hepatozoon (H. spp. Antibodies against E. canis and A. phagocytophilum/platys were detected using commercial immunochromatography tests. Records of the dogs were examined retrospectively to obtain clinical and laboratory data. PRINCIPAL FINDINGS: There was serological and/or PCR evidence of infections of dogs with E. canis (27%; 46/170, Babesia spp. (24%; 90/372 including B. canis vogeli (12%; 43/372 and B. gibsoni (10%; 36/372, A. platys (11%; 17/157 and H. canis (6%; 15/266. We could not identify the Babesia sp. detected in nine dogs. There was evidence of multiple infections with dual infections with E. canis and B. canis vogeli (8%; 14/179 or B. gibsoni (7%; 11/170 being the most common. There was agreement between immunochromatography and PCR test results for E. canis for 87% of dogs. Only 13% of exposed dogs had signs of a tick-borne disease and 38% had laboratory abnormalities. All 10 dogs presenting for a recheck after treatment of E. canis with doxycycline were apparently healthy although all remained seropositive and six still had laboratory abnormalities despite an average of two treatments with the most recent being around 12 months previously. Infections with Babesia spp. were also mainly subclinical with only 6% (4/67 showing clinical signs and 13% (9/67 having laboratory abnormalities. Similarly, animals with evidence of infections with A. platys and H. canis were largely apparently healthy with only occasional laboratory abnormalities. CONCLUSIONS: Dogs are commonly infected with tick-borne pathogens in the Caribbean with most having no clinical signs or laboratory abnormalities.

Ehrlichiosis, Babesiosis, Anaplasmosis and Hepatozoonosis in Dogs from St. Kitts, West Indies

Science.gov (United States)

Kelly, Patrick J.; Xu, Chuanling; Lucas, Helene; Loftis, Amanda; Abete, Jamie; Zeoli, Frank; Stevens, Audrey; Jaegersen, Kirsten; Ackerson, Kate; Gessner, April; Kaltenboeck, Bernhard; Wang, Chengming

2013-01-01

Background Although tick-borne diseases are important causes of morbidity and mortality in dogs in tropical areas, there is little information on the agents causing these infections in the Caribbean. Methodology We used PCRs to test blood from a cross-section of dogs on St Kitts for Ehrlichia (E.) canis, Babesia (B.) spp., Anaplasma (A.) spp. and Hepatozoon (H.) spp. Antibodies against E. canis and A. phagocytophilum/platys were detected using commercial immunochromatography tests. Records of the dogs were examined retrospectively to obtain clinical and laboratory data. Principal findings There was serological and/or PCR evidence of infections of dogs with E. canis (27%; 46/170), Babesia spp. (24%; 90/372) including B. canis vogeli (12%; 43/372) and B. gibsoni (10%; 36/372), A. platys (11%; 17/157) and H. canis (6%; 15/266). We could not identify the Babesia sp. detected in nine dogs. There was evidence of multiple infections with dual infections with E. canis and B. canis vogeli (8%; 14/179) or B. gibsoni (7%; 11/170) being the most common. There was agreement between immunochromatography and PCR test results for E. canis for 87% of dogs. Only 13% of exposed dogs had signs of a tick-borne disease and 38% had laboratory abnormalities. All 10 dogs presenting for a recheck after treatment of E. canis with doxycycline were apparently healthy although all remained seropositive and six still had laboratory abnormalities despite an average of two treatments with the most recent being around 12 months previously. Infections with Babesia spp. were also mainly subclinical with only 6% (4/67) showing clinical signs and 13% (9/67) having laboratory abnormalities. Similarly, animals with evidence of infections with A. platys and H. canis were largely apparently healthy with only occasional laboratory abnormalities. Conclusions Dogs are commonly infected with tick-borne pathogens in the Caribbean with most having no clinical signs or laboratory abnormalities. PMID:23335965

Nonoverlapping Clinical and Mutational Patterns in Melanomas from the Female Genital Tract and Atypical Genital Nevi.

Science.gov (United States)

Yélamos, Oriol; Merkel, Emily A; Sholl, Lauren Meldi; Zhang, Bin; Amin, Sapna M; Lee, Christina Y; Guitart, Gerta E; Yang, Jingyi; Wenzel, Alexander T; Bunick, Christopher G; Yazdan, Pedram; Choi, Jaehyuk; Gerami, Pedram

2016-09-01

Genital melanomas (GM) are the second most common cancer of the female external genitalia and may be confused with atypical genital nevi (AGN), which exhibit atypical histological features but have benign behavior. In this study, we compared the clinical, histological, and molecular features of 19 GM and 25 AGN. We described chromosomal copy number aberrations and the mutational status of 50 oncogenes and tumor suppressor genes in both groups. Our study showed that a pigmented lesion occurring in mucosal tissue, particularly in postmenopausal women, was more likely to be a melanoma than a nevus. GM had high levels of chromosomal instability, with many copy number aberrations. Furthermore, we found a completely nonoverlapping pattern of oncogenic mutations when comparing GM and AGN. In GM, we report somatic mutations in KIT and TP53. Conversely, AGN had frequent BRAF V600E mutations, which were not seen in any of the GM. Our results show that GM and AGN have distinct clinical and molecular changes and that GM have a different mutational pattern compared with AGN. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

Facts and fiction: the death of Saint Ignatius of Loyola.

Science.gov (United States)

Rosenman, L D

1996-01-01

The biography of Ignatius of Loyola, the sainted founder of the Society of Jesus (the Jesuits), ends with his death in curious circumstances. A careful search of the available sources written from the time of his death in 1556 to the present has reviewed the evidence. The evidence does not support the claims for a diagnosis that has been used for four centuries. So-called historical "facts" simply are the opinions of historians. Ignatius may have suffered from hyperparathyroidism that led to his death rather than from a cholangioportal venous fistula.

To build an environmental quality building. Evaluation: the HQE secondary school of Pic Saint Loup realized by the region; Construire un batiment respectueux de l'environnement. Retour d'experience: le Lycee HQE du Pic Saint Loup realise par la Region

Energy Technology Data Exchange (ETDEWEB)

Denicourt, Ch.

2004-07-01

This document presents the action realized in Pic Saint Loup secondary school, concerning the program management of an environmental quality building (HQE). The 8 chapters details the realization of the HQE building, the project planing of a HQE building, the Pic Saint Loup project, the operation beginning, the planing implementing, the project feasibility evaluation, the program redaction and the time and cost evaluation. (A.L.B.)

Development of flood-inundation maps for the Mississippi River in Saint Paul, Minnesota

Science.gov (United States)

Czuba, Christiana R.; Fallon, James D.; Lewis, Corby R.; Cooper, Diane F.

2014-01-01

Digital flood-inundation maps for a 6.3-mile reach of the Mississippi River in Saint Paul, Minnesota, were developed through a multi-agency effort by the U.S. Geological Survey in cooperation with the U.S. Army Corps of Engineers and in collaboration with the National Weather Service. The inundation maps, which can be accessed through the U.S. Geological Survey Flood Inundation Mapping Science Web site at http://water.usgs.gov/osw/flood_inundation/ and the National Weather Service Advanced Hydrologic Prediction Service site at http://water.weather.gov/ahps/inundation.php, depict estimates of the areal extent and depth of flooding corresponding to selected water levels (stages) at the U.S. Geological Survey streamgage at the Mississippi River at Saint Paul (05331000). The National Weather Service forecasted peak-stage information at the streamgage may be used in conjunction with the maps developed in this study to show predicted areas of flood inundation. In this study, flood profiles were computed for the Mississippi River by means of a one-dimensional step-backwater model. The hydraulic model was calibrated using the most recent stage-discharge relation at the Robert Street location (rating curve number 38.0) of the Mississippi River at Saint Paul (streamgage 05331000), as well as an approximate water-surface elevation-discharge relation at the Mississippi River at South Saint Paul (U.S. Army Corps of Engineers streamgage SSPM5). The model also was verified against observed high-water marks from the recent 2011 flood event and the water-surface profile from existing flood insurance studies. The hydraulic model was then used to determine 25 water-surface profiles for flood stages at 1-foot intervals ranging from approximately bankfull stage to greater than the highest recorded stage at streamgage 05331000. The simulated water-surface profiles were then combined with a geographic information system digital elevation model, derived from high-resolution topography

Situation Reports--Afghanistan, Bahrein, Brazil, Ecuador, Indonesia, Iraq, Morocco, Paraguay, People's Democratic Republic of Yemen, Peru, Qatar, Saudi Arabia, Sri Lanka, St. Christopher/Nevis, Sudan, United Arab Emirates, Yemen Arab Republic.

Science.gov (United States)

International Planned Parenthood Federation, London (England).

Data relating to population and family planning in 17 foreign countries are presented in these situation reports. Countries included are Afghanistan, Bahrein, Brazil, Ecuador, Indonesia, Iraq, Morocco, Paraguay, People's Democratic Republic of Yemen, Peru, Qatar, Saudi Arabia, Sri Lanka, St. Christopher/Nevis, Sudan, United Arab Emirates, and…

Consistent initial conditions for the Saint-Venant equations in river network modeling

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C.-W. Yu

2017-09-01

Full Text Available Initial conditions for flows and depths (cross-sectional areas throughout a river network are required for any time-marching (unsteady solution of the one-dimensional (1-D hydrodynamic Saint-Venant equations. For a river network modeled with several Strahler orders of tributaries, comprehensive and consistent synoptic data are typically lacking and synthetic starting conditions are needed. Because of underlying nonlinearity, poorly defined or inconsistent initial conditions can lead to convergence problems and long spin-up times in an unsteady solver. Two new approaches are defined and demonstrated herein for computing flows and cross-sectional areas (or depths. These methods can produce an initial condition data set that is consistent with modeled landscape runoff and river geometry boundary conditions at the initial time. These new methods are (1 the pseudo time-marching method (PTM that iterates toward a steady-state initial condition using an unsteady Saint-Venant solver and (2 the steady-solution method (SSM that makes use of graph theory for initial flow rates and solution of a steady-state 1-D momentum equation for the channel cross-sectional areas. The PTM is shown to be adequate for short river reaches but is significantly slower and has occasional non-convergent behavior for large river networks. The SSM approach is shown to provide a rapid solution of consistent initial conditions for both small and large networks, albeit with the requirement that additional code must be written rather than applying an existing unsteady Saint-Venant solver.

San Jose Accord: energy aid or petroleum-marketing strategy

Energy Technology Data Exchange (ETDEWEB)

1982-09-30

The San Jose Accord was signed in San Jose, Costa Rica on August 3, 1980 by the Presidents of Venezuela and Mexico, whereby the two countries mutually committed to supply the net imported domestic oil consumption of several Central American and Caribbean countries. Countries initially participating in the program are: Barbados, Costa Rica, Dominican Republic, El Salvador, Guatemala, Honduras, Jamaica, Nicaragua, and Panama. Seven eastern Caribbean countries were to meet on October 7 to petition for inclusion in the Accord, namely: Antigua, St. Kitt/Nevis, Montserrat, Dominica, St. Lucia, St. Vincent, and Grenada. The official language of the Accord is presented, and the operative status of the Accord two years after signing is discussed. Specific briefs about some of the individual countries in the Accord are included. The fuel price/tax series for the Western Hemisphere countries is updated.

Three saints with deformed extremities in an Italian Renaissance altarpiece.

Science.gov (United States)

Albury, W R; Weisz, G M

2017-03-01

A fifteenth-century Florentine altarpiece painted by the Pollaiuolo brothers, Antonio (1433-1498) and Piero (1443-1496), shows three saints with evident deformities of the hands and feet. The pathologies concerned are tentatively identified, and various rationales for their presence in the painting are discussed. Of particular importance is the location of the altarpiece in a chapel which houses the tomb of the Cardinal of Portugal, Prince James of Lusitania (1433-1459). It is argued that both the artistic style of the day and the religious symbolism of the Cardinal's funeral chapel contributed to the artists' decision to portray the saints with deformities. An unnatural curvature of the fifth finger was apparently considered elegant in fifteenth-century paintings, and the depiction of bare feet with hallux valgus gave them a shape which approximated and could have been caused by fashionable pointed shoes. But in addition, deformities in religious art could be symbolic of suffering and martyrdom, a theme which the Cardinal's chapel emphasised in a number of ways. It is suggested therefore that the Pollaiuolo altarpiece reconciles these two disparate factors, portraying genuine deformities in a way that was artistically stylish and symbolically meaningful.

Saint Venant's equation and theory of characteristics

International Nuclear Information System (INIS)

Daubert, Andre

1978-01-01

This theory, in its general scope, will be dealt with through the concrete example of Saint Venant's equations which govern the waves in channels. 1. Finding the characteristic directions. The aim is to interpret the hyperbolic sort of equations to show that there is a way of combining them in order to shape them so that they express a linear relation between the variations of the unknowns when moving along particular differential paths. In certain cases, this differential relation can integrate to lead to Rieman's invariants. 2. Relation between the theory of characteristics and the wave equation. In the linear systems case, it is worthwhile showing simply, how the method of characteristics is linked to the conventional treatment of the wave equation. 3. Relation between the theory of characteristics and the Cauchy problem. The theory of characteristics is frequently introduced as from the Cauchy problem, the characteristics forming the conditions of indetermination of the Cauchy problem [fr

Consumer preferences and willingness to pay for compact fluorescent lighting: Policy implications for energy efficiency promotion in Saint Lucia

International Nuclear Information System (INIS)

Reynolds, Travis; Kolodinsky, Jane; Murray, Byron

2012-01-01

This article examines consumer willingness to pay for energy-saving compact fluorescent light bulbs using the results of a stated preferences study conducted in the Caribbean island nation of Saint Lucia. Geographic location, low income status, and age are found to affect willingness-to-pay for compact fluorescent lighting, while higher income status and other demographic variables appear to have minimal or no significant impacts. Energy efficiency knowledge is associated with increased willingness-to-pay for energy-efficient bulbs and with increased use of compact fluorescent lighting. Contrary to theoretical expectations, past purchase of compact fluorescent bulbs is found to have no impact on self-reported willingness to pay. We hypothesize that this null result is due to the recent emergence of low-cost, low-quality compact fluorescent bulbs in the Saint Lucian lighting market, which may be negatively influencing consumers' preferences and expectations regarding energy-efficient lighting. Findings support the argument that government-sponsored education and subsidy programs will likely result in increased use of energy-saving technologies in Saint Lucia. But such behavioral changes may not be sustained in the long run unless low quality bulbs – the “lemons” of the compact fluorescent lighting market – can be clearly identified by consumers. - Highlights: ▶ We model how knowledge, attitudes, and past purchase affect CFL adoption. ▶ Saint Lucian consumers have some knowledge of and favorable attitudes toward CFLs. ▶ Energy efficiency knowledge increases stated willingness-to-pay (WTP) for CFLs. ▶ Past purchase does not increase WTP; low-quality ‘lemons’ may influence consumers. ▶ Policy can lower consumer risks in lighting markets where low quality bulbs exist.

Nondestructive evaluation of the oxidation and strength of the Fort Saint Vrain HTGR support block

International Nuclear Information System (INIS)

Tingey, G.L.; Posakony, G.J.; Morgan, W.C.; Prince, J.M.; Hill, R.W.; Lessor, D.L.

1982-04-01

Non-destructive detection of changes in the strength of graphite support structures in a HTGR appears to be feasible using sonic velocity measurements where access for through transmission is possible. Therefore, future HTGR designs should consider providing such access. Where access is not available, strength changes can be correlated with oxidation profiles in the support member. These oxidation profiles can be determined non-destructively by a combination of eddy current measurements to detect near surface oxidation and sonic backscattering measurements designed to determine oxidation in depth. The Fort Saint Vrain reactor provides an operating reactor to test the applicability of the eddy current and sonic backscattering techniques for determination of oxidation in a support block. Furthermore, such tests in Fort Saint Vrain will supply base line data which will be useful in assuring an adequate strength of the support structure for the lifetime of the reactor. Equipment is, therefore, being developed for tests to be conducted during the next major refueling of the reactor

Le système du risque à Saint-Martin (Petites Antilles françaises

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Virginie Duvat

2008-11-01

Full Text Available L’île de Saint-Martin constitue un terrain particulièrement intéressant pour étudier le système du risque naturel et les conditions de la co-évolution territoire/catastrophes. Les mécanismes qui s’y observent renforcent sa vulnérabilité et l’efficacité du retour d’expérience est affaiblie par des blocages d’ordre politique et juridique.The island of Saint-Martin is an interesting case study for a systemic approach applied to cyclone hazards and the co-evolution of territory and disaster management. The mecanisms which can be observed increase its vulnerability and the progress of hazard management policies is weakened by political and juridical bottlenecks.

Operator modeling of a loss-of-pumping accident using MicroSAINT

International Nuclear Information System (INIS)

Olsen, L.M.

1992-01-01

The Savannah River Laboratory (SRL) human factors group has been developing methods for analyzing nuclear reactor operator actions during hypothetical design-basis accident scenarios. The SRL reactors operate at a lower temperature and pressure than power reactors resulting in accident sequences that differ from those of power reactors. Current methodology development is focused on modeling control room operator response times dictated by system event times specified in the Savannah River Site Reactor Safety Analysis Report (SAR). The modeling methods must be flexible enough to incorporate changes to hardware, procedures, or postulated system event times and permit timely evaluation. The initial model developed was for the loss-of-pumping accident (LOPA) because a significant number of operator actions are required to respond to this postulated event. Human factors engineers had been researching and testing a network modeling simulation language called MicroSAINT to simulate operators' personal and interpersonal actions relative to operating system events. The LOPA operator modeling project demonstrated the versatility and flexibility of MicroSAINT for modeling control room crew interactions

Compressive strength evolution of thermally-stressed Saint Maximin limestone.

Science.gov (United States)

Farquharson, J.; Griffiths, L.; Baud, P.; Wadsworth, F. B.; Heap, M. J.

2017-12-01

The Saint Maximin quarry (Oise, France) opened in the early 1600s, and its limestone has been used extensively as masonry stone, particularly during the classical era of Parisian architecture from the 17th century onwards. Its widespread use has been due to a combination of its regional availability, its high workability, and its aesthetic appeal. Notable buildings completed using this material include sections of the Place de la Concorde and the Louvre in Paris. More recently, however, it has seen increasing use in the construction of large private residences throughout the United States as well as extensions to private institutions such as Stanford University. For any large building, fire hazard can be a substantial concern, especially in tectonically active areas where catastrophic fires may arise following large-magnitude earthquakes. Typically, house fires burn at temperatures of around 600 °C ( 1000 F). Given the ubiquity of this geomaterial as a building stone, it is important to ascertain the influence of heating on the strength of Saint Maximin limestone (SML), and in turn the structural stability of the buildings it is used in. We performed a series of compressive tests and permeability measurements on samples of SML to determine its strength evolution in response to heating to incrementally higher temperatures. We observe that the uniaxial compressive strength of SML decreases from >12 MPa at room temperature to 400 °C). We anticipate that this substantial weakening is in part a result of thermal microcracking, whereby changes in temperature induce thermal stresses due to a mismatch in thermal expansion between the constituent grains. This mechanism is compounded by the volumetric increase of quartz through its alpha - beta transition at 573 °C, and by the thermal decomposition of calcite. To track the formation of thermal microcracks, we monitor acoustic emissions, a common proxy for microcracking, during the heating of an SML sample. The

Prayer to the Saints or the Virgin and Health among Older Mexican Americans

Science.gov (United States)

Krause, Neal; Bastida, Elena

2011-01-01

The purpose of this study was to evaluate a conceptual model that assesses whether praying to the saints or the Virgin is associated with the health of older Mexican Americans. A survey was conducted of 1,005 older Mexican Americans (Mean age = 73.9 years; SD = 6.6 years). Data from 795 of the Catholic respondents are presented in this study. The…

Das Weiblich-Männliche in der saint-simonistischen Debatte um 1830

Directory of Open Access Journals (Sweden)

Paola Ferruta

2009-12-01

Full Text Available D’une part, ma contribution interroge les concepts saint-simoniens de « masculin » et de « féminin » en se basant sur le cas concret de Pierre Leroux, adepte du saintsimonisme dès 1830 à Paris ; d’autre part, elle revient sur la notion d’identité sexuée, ainsi que sur sa variabilité intrinsèque. L’initiative politique et théorétique de Leroux au sein du groupe saint-simonien présente un intérêt historique, car elle a notamment participé à la diffusion au cours du XIXe siècle des croyances en la métempsychose et en des « vérités mystiques ». Ces « vérités mystiques » ont contribué à définir les identités de « genre » dans la pensée de Leroux et à façonner autour de 1840 son concept de « solidarité ». Or la question d’une « politique de la solidarité », et particulièrement de la « solidarité de genre » – c’est-à-dire d’une solidarité féminine qui ne fasse pas du féminisme une politique identitaire – est réactualisée dans le débat contemporainDie saint-simonistischen Begriffe „männlich“ und „weiblich“ sollen hier anhand des Falles von Pierre Leroux, einem Pariser Aktivisten des Saint-Simonismus, betrachtet werden. Es wird u. a. dessen Vorstellung von geschlechtlicher Identität und ihrer inhärenten Variabilität ins Auge gefasst. Die politische und theoretische Initiative Leroux’ ist insofern von historischem Interesse als sie zur Verbreitung des Glaubens an die Metempsychose und an „mystische Wahrheiten“ beitrug. Diese „mystischen Wahrheiten“ steuerten in Leroux’ Denken zur Definition der Geschlechteridentitäten bei und formten um 1840 seinen Begriff von „Solidarität“. Die Frage der „Politik der Solidarität“ ist heute noch aktuell, insbesondere einer „Geschlechtsidentität“, d. h. einer weiblichen Solidarität, die den Feminismus nicht als Identitätspolitik artikuliert.

Recherche sur les sous-declarations de décés, Saint Marc, Haiti, 2012

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Stela Nazareth Meneghel

2014-11-01

Full Text Available Ce travail se réfère à une étude exploratoire menée dans la ville de Saint Marc, une commune d'environ 257,863 habitants en 2012, localisée dans le département d'Artibonite/Haïti. L'objectif est rechercher le flux d'informations concernant le système de mortalité et l'existence de non-déclarations de décès. Les décès survenus dans le mois de janvier 2013 ont fait l'objet d'une enquête dans cinq institutions de la ville de Saint Marc: l'Hôpital Saint Nicolas (HSN, la Mairie, le Bureau d'État Civil (BEC, le Cimetière et la Cathédrale. L'hôpital a été l'institution où l'on a rencontré le plus grand nombre de décès enregistrés. On a procédé au comptage des décès, à partir de la liste nominale des registres hospitaliers, en ajoutant les décè...

Marées et touristes au Mont-Saint-Michel

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Fernand Verger

2001-09-01

Full Text Available L’imaginaire collectif fait la plus grande place au phénomène des grandes marées dans la baie du Mont-Saint-Michel, mais la fréquentation touristique n’est que faiblement déterminée par l’occurrence des grandes marées, malgré l’existence d’un public spécifique, relativement peu nombreux, attiré par le spectacle du mascaret.

[Department of Otorhinolaryngology of the I.P. Pavlov Saint-Peterburg First State Medical University].

Science.gov (United States)

Karpishchenko, S A

This article is designed to report the results of the analysis ofacademic, scientific, and clinical activities of the Department of Otorhinolaryngology of the I.P. Pavlov Saint-Peterburg First State Medical University.

Saint-Lupicin (Jura, étude de bâti de l’église Notre-Dame

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Aurélia Bully

2007-08-01

Full Text Available Modalités de l’opération et problématiquesL’église de Saint-Lupicin fait l’objet depuis mai 2006 d’un important chantier de restauration sous la conduite de P. Barnoud, Architecte en chef des Monuments historiques. Les travaux portent essentiellement sur le remplacement de la toiture de la nef dont l’état de dégradation menaçait la pérennité de l’ouvrage. Après que la maîtrise d’ouvrage (commune de Saint-Lupicin eut choisi de restituer une charpente à quatre pans dans l’esprit du parti d’ori...

Christian Feasts dedicated to Saints – an Interdisciplinary Perspective

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Carmen-Maria Bolocan

2012-06-01

Full Text Available Our paper is an interdisciplinary approach, of linguistic and theological analysis of a few lexemes that define saints who became popular in the Romanian culture and spirituality. Our ancient church, a fundamental part of our culture, has always been a coagulant factor for the unity of the Romanians worldwide. And this is also proven by the use of the religious vocabulary in all the anthropological, territorial, socio-professional and socio-cultural variants of the national Romanian language.

Pigmentary Markers in Danes – Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome

DEFF Research Database (Denmark)

Johansen, Peter; Andersen, Jeppe Dyrberg; Madsen, Linnea Nørgård

2016-01-01

pigmentation measured on the buttock area. We hypothesize that the effect of MC1R variants on arm pigmentation is primarily reflecting the inability to tan when subjected to UVR. A gender specific effect on skin pigmentation was also observed, and it was found that the skin pigmentation of females on average......To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis) contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total nevus count, and the familial atypical...... variants (missense, NM_002386:c. 456C > A (p.TYR152*), or NM_002386:c.83_84insA (p.Asn29Glnfs*14) had significantly (pskin pigmentation of the upper-inner arm than those with none or one MC1R variant. We did not observe any significant association of the MC1R variants with constitutive...

Business plan of a food truck in Saint Petersburg

OpenAIRE

Zavyalova, Ekaterina

2017-01-01

The purpose of the thesis was to investigate how to write a proper business plan and then implement gained knowledge in creating a business plan of a food truck in Saint Petersburg. A business plan serves as a guide for an entrepreneur in the process of company establishment and enables to gain funding from potential investors. The primary objective was to study essential components of a business plan. The theoretical framework comprises of core issues on company establishment and desc...

Saints' Relics in Scuola di S. Giorgio degli Schiavoni: An Anti-Ottoman Pantheon

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Ana Marinković

2018-04-01

Full Text Available The intensified military campaigns against the Ottomans in the second half of the fifteenth century palpably influenced the cult of saints venerated in Scuola di S. Giorgio degli Schiavoni, both by assimilating new saints, as well as strenghtening the existing cults through indulgences and relic acquisitions. The initial pair of patron saints – St George and St Tryphon, the city patrons of Bar and Kotor – delineated the geographical area where the majority of confraternity members originated from, that is, the Venetian Albania. The inclusion of St Jerome, the patron of Dalmatia, to the confraternal pantheon by Cardinal Bessarion's indulgence issued in 1464, in addition to rounding up the holy patronage to all the Eastern Adriatic Venetian dependencies, also marked the beginning of a strong anti-Ottoman motivation in the scuola's hagiographic horizon. The triple endowment of the Scuola in 1502 – relic acquisition, granting of indulgence, and commission of Carpaccio's monumental cycle – continued to work on the same line, and added to the practical aspect of spiritual support to the members of Venetian troops provenient of the Eastern Adriatic. However, the saints whose relics are today kept in the altar of the lower hall, including the patron saint of the Republic of Dubrovnik, point to an even wider devotional agenda, possibly arranged after the Battle of Lepanto, as the comparative analysis of the reliquaries show.   Le campagne militari contro gli Ottomani intensificatesi nella seconda metà del XV secolo influenzarono palesemente il culto dei santi venerati nella Scuola di S. Giorgio degli Schiavoni, sia attraverso l'assimilazione di nuovi santi, sia tramite il rafforzamento del culto già esistente verso le indulgenze e l'impulso all'acquisizione di reliquie. La prima coppia di santi patroni - San Giorgio e San Trifone, patroni della città di Bar e Cattaro - delimitano l'area geografica da cui proviene la maggior parte dei membri

A Comparative Case Study of Self-Actualization in Eleanor Roosevelt and Antoine de Saint-Exupery.

Science.gov (United States)

Tyska, Cynthia Ann

Eleanor Roosevelt and Antoine de Saint-Exupery are described as strongly developed self-actualizing people. They were selected as subjects of this study because they are generally believed to possess self-actualizing characteristics and because their positions as public figures made it more likely that data on them would be accessible.…

Prevalence of overweight, obesity and underweight among 5-year-old children in Saint Lucia by three methods of classification and a comparison with historical rates.

Science.gov (United States)

Gardner, K; Bird, J; Canning, P M; Frizzell, L M; Smith, L M

2011-01-01

The study aimed to determine if child obesity rates have risen in the Caribbean nation of Saint Lucia, as found globally, and whether under-nutrition coexists, as in other developing nations. The average adult in Saint Lucia is overweight, thus considerable child obesity might be expected, but there are no current data. Heights and weights were obtained from a sample (n= 425) of the 2001 birth cohort of Saint Lucian children measured during the nation-wide 2006/2007 Prior to School Entry Five-Year Assessment. Prevalence of overweight, obesity and underweight were estimated by Centers for Disease Control (CDC), Cole et al. and new World Health Organization (WHO) methods. Previously reported 1976 estimates, including children ≤60 months of age only, based on National Centre for Health Statistics curves, were adjusted to new WHO equivalents using an algorithm developed by Yang and de Onis, and compared with rates in our subsample of children ≤60 months of age (n= 99). Regardless of classification method, overweight and obesity rates were high: 14.4% and 9.2% (WHO); 11.3% and 12.0% (CDC); and 9.9% and 7.1% (Cole et al.), respectively. Underweight estimates also varied: 4.7% (WHO); 11.3% (CDC) and 6.6% (Cole et al.). Obesity in our young subsample (15.2%; WHO) was more than 3 times the adjusted 1976 rate (4.3%). Obesity among Saint Lucian pre-schoolers has tripled in 30 years. Our findings also suggest that this country, like many undergoing a 'nutrition transition', faces the dual challenge of over-nutrition and under-nutrition. Routine monitoring of overweight and underweight is needed in Saint Lucia, as is the implementation and evaluation of programmes to address these problems. © 2010 Blackwell Publishing Ltd.

Baking the Bread and Roasting the Meat : Dorlandus's Saint Lawrence as a model for Carthusians

NARCIS (Netherlands)

van Dijk, Mathilde

2018-01-01

The two sermons on Saint Lawrence by the profilic Carthusian author Petrus Dorlandus survive in a manuscript from the charterhouse in Louvain, which was used for reading at table. Dorlandus’s development of the well-known tale about this martyr is geared to this practice. Inviting his fellow

El diario de un escritor en Encuentro en Saint-Nazaire de Ricardo Piglia

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Amor Arelis Hernández Peñaloza

2016-01-01

Full Text Available En este artículoestudiamos el género diario íntimo a través de la nouvelleEncuentro en Saint-Nazaire(1988 que contiene el ”Diario de un loco”del escritor ficticio Stephen Stevensen. Este uso ficcional del diario, dentro delmarco de la estructura de la obra literaria adquiere un sentido diferente porque renuncia a la comunicación de algo íntimo y secreto, para convertirse en literatura, en ”comunicación estética”. Asimismopretendemosevidenciar la importancia y la magnitud del género diario en la unidad narrativa de un autor como Ricardo Piglia. Junto a esto, el ejemplo de Encuentro en Saint- Nazairenos ayudará a mostrar las características de este tipo de prosa pigliana, que funciona como un laboratorio de la escritura.

Comportamiento de las ecuaciones de Saint-Venant en 1D y aproximaciones para diferentes condiciones en régimen permanente y variable

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Gloria Estefany Amarís Castro

2015-07-01

Full Text Available The importance of the behavior of the Saint Venant equations and its implications for flow analysis applied to models of hydraulic transit is the main theme of this research, where the basis of the applications and uses of these mathematical models is determined and the performance is evaluated these equations in 1D and possible approaches for different conditions of a real situation using computational numerical experimentation for a section of a prismatic channel with a hydraulic section, in cases where the channel slope presents three types of conditions: supercritical, subcritical and horizontal slope for a design rate. The main objective of this research is to find a demonstration of the applicability of the Saint Venant equations for different conditions of approaching this problem from the point of view of the solution of the Saint Venant equations in one dimension. Scheme simple solution that produce useful solutions to the needs of engineering and found to be within the sewer network analysis, many factors can affect the solution of the Saint Venant equations is proposed.

Saint Francis Xavier on Jesuit School Stages of the Bohemian Province

Czech Academy of Sciences Publication Activity Database

Bobková, Kateřina; Jacková, Magdaléna

2015-01-01

Roč. 25, č. 2 (2015), s. 135-155 ISSN 0515-3190 R&D Projects: GA ČR GPP406/12/P823 Institutional support: RVO:68378068 ; RVO:67985963 Keywords : St. Francis Xavier * Jesuit saints * Jesuit theatre * neolatin drama * school theatre * Avancini, Nicolaus * Engel, Arnoldus Subject RIV: AJ - Letters, Mass-media, Audiovision; AB - History (HIU-Y)

FOOLISHNESS FOR CHRIST, LOVE AND MATERNITY IN LUDMILA ULITSKAYA'S PLAY "THE SEVEN SAINTS"

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Moteyunaite I. V.

2008-11-01

Full Text Available The article presents a new understanding of such a complex cultural phenomenon as foolishness for Christ through the example of Ludmila Ulitskaya's historical play "The Seven Saints". The author shows that the hero of the 1990's became a blessed woman (a God's fool, who neither sets an optimistic example nor gives faith in the triumph of spirit, but who can only die with dignity, following Christ's way and His final sacrifice.

Urban growth and cultural identity; fractures and imbalances in heritage values: A case study of the island of Saint-Louis, Senegal

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Lucía Martínez-Quintana

2016-05-01

Full Text Available The island of Saint-Louis of Senegal was awarded the status of world heritage site by UNESCO in 2000 as an “outstanding example” of urban heritage. This island city comes with a unique heritage: development planning that combines a strong historical French influence with a gridiron urban morphology and building typology. The island must be interpreted within its total territorial context that includes both the island of Sor (on the mainland and La Langue de la Barberie, a sandy barrier that separates the mouth of the river from the sea. The city of Saint-Louis itself has grown enormously and haphazardly from the latter part of the 20th century: it is now the fourth most populous city in Senegal. At present, the city is undergoing a serious period of decline and recession due, in part, to the overriding influence of the capital, Dakar, and the centralized political forces in the country. This article looks at the key morphological and functional reasons behind the development and evolution of the island of Saint-Louis and that persist in the present context, with justifications for the deep-rooted heritage values that maintain its prestige as a World Heritage Site.

Effects of Protection and Sediment Stress on Coral Reefs in Saint Lucia.

Science.gov (United States)

Bégin, Chantale; Schelten, Christiane K; Nugues, Maggy M; Hawkins, Julie; Roberts, Callum; Côté, Isabelle M

2016-01-01

The extent to which Marine Protected Areas (MPAs) benefit corals is contentious. On one hand, MPAs could enhance coral growth and survival through increases in herbivory within their borders; on the other, they are unlikely to prevent disturbances, such as terrestrial runoff, that originate outside their boundaries. We examined the effect of spatial protection and terrestrial sediment on the benthic composition of coral reefs in Saint Lucia. In 2011 (10 to 16 years after MPAs were created), we resurveyed 21 reefs that had been surveyed in 2001 and analyzed current benthic assemblages as well as changes in benthic cover over that decade in relation to protection status, terrestrial sediment influence (measured as the proportion of terrigenous material in reef-associated sediment) and depth. The cover of all benthic biotic components has changed significantly over the decade, including a decline in coral and increase in macroalgae. Protection status was not a significant predictor of either current benthic composition or changes in composition, but current cover and change in cover of several components were related to terrigenous content of sediment deposited recently. Sites with a higher proportion of terrigenous sediment had lower current coral cover, higher macroalgal cover and greater coral declines. Our results suggest that terrestrial sediment is an important factor in the recent degradation of coral reefs in Saint Lucia and that the current MPA network should be complemented by measures to reduce runoff from land.

Effects of Protection and Sediment Stress on Coral Reefs in Saint Lucia.

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Chantale Bégin

Full Text Available The extent to which Marine Protected Areas (MPAs benefit corals is contentious. On one hand, MPAs could enhance coral growth and survival through increases in herbivory within their borders; on the other, they are unlikely to prevent disturbances, such as terrestrial runoff, that originate outside their boundaries. We examined the effect of spatial protection and terrestrial sediment on the benthic composition of coral reefs in Saint Lucia. In 2011 (10 to 16 years after MPAs were created, we resurveyed 21 reefs that had been surveyed in 2001 and analyzed current benthic assemblages as well as changes in benthic cover over that decade in relation to protection status, terrestrial sediment influence (measured as the proportion of terrigenous material in reef-associated sediment and depth. The cover of all benthic biotic components has changed significantly over the decade, including a decline in coral and increase in macroalgae. Protection status was not a significant predictor of either current benthic composition or changes in composition, but current cover and change in cover of several components were related to terrigenous content of sediment deposited recently. Sites with a higher proportion of terrigenous sediment had lower current coral cover, higher macroalgal cover and greater coral declines. Our results suggest that terrestrial sediment is an important factor in the recent degradation of coral reefs in Saint Lucia and that the current MPA network should be complemented by measures to reduce runoff from land.

Ecole d’été de probabilités de Saint-Flour XXXII

CERN Document Server

2004-01-01

This is yet another indispensable volume for all probabilists and collectors of the Saint-Flour series, and is also of great interest for mathematical physicists. It contains two of the three lecture courses given at the 32nd Probability Summer School in Saint-Flour (July 7-24, 2002). Boris Tsirelson's lectures introduce the notion of nonclassical noise produced by very nonlinear functions of many independent random variables, for instance singular stochastic flows or oriented percolation. Two examples are examined (noise made by a Poisson snake, the Brownian web). A new framework for the scaling limit is proposed, as well as old and new results about noises, stability, and spectral measures. Wendelin Werner's contribution gives a survey of results on conformal invariance, scaling limits and properties of some two-dimensional random curves. It provides a definition and properties of the Schramm-Loewner evolutions, computations (probabilities, critical exponents), the relation with critical exponents of planar...

76 FR 555 - Keystone Holdings, LLC and Compagnie de Saint-Gobain; Analysis of Proposed Agreement Containing...

Science.gov (United States)

2011-01-05

... Asia for a purchase price of $245 million. As originally structured, the assets acquired by Keystone... future, or that Saint-Gobain could sell the business upon terms that would reduce competition in the North American alumina wear tile markets. Therefore, the proposed Consent Agreement requires that...

[The embroidery work of the lady at Saint-Anne Hospital].

Science.gov (United States)

Thillaud, Pierre L; Postel, Jacques

2014-01-01

In July 1974, a 72 old woman had been a patient for forty years in Sainte-Anne Hospital, Ward C. As she had again a violent brawl with her neighbour patient, she revealed being a tremendous artist. She had been confined on account of dementia paralytica in the Mecca of malariotherapy, and passionately devoted herself to embroidery. Her fancy work was rather a matter for Jean Dubuffet's art through its perfect expression and deserved being known.

Historical basis of the Miracula of Saint Symeon in Stefan the First-Crowned’s life of Symeon

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Komatina Ivana

2014-01-01

Full Text Available The paper is devoted to the research of the so-called Catalog of Miracles in the Life of Saint Symeon by Stefan the First-Crowned. Because the miracles are divided in the Life into those in which Symeon-Nemanja is revealed as a Saint, and those in which his heir Stefan the First-Crowned conquers the enemies of the Serbian State with his help, the attention is paid on research of their historical basis and chronological frame, as well as their religious essence. [Projekat Ministarstva nauke Republike Srbije, br. 177029: Srednjovekovne srpske zemlje (13-15. vek: politički, privredni, društveni i pravni procesi

Enhancing the IT Infrastructure at Saint Philip's Hospital: Point-of-Care Solutions

Science.gov (United States)

Naydenova, Iva; White, Bruce

2013-01-01

Healthcare has become a rapidly changing field. With the introduction of value-based purchasing to determine reimbursement of Medicare providers based on the quality of care in addition to outcomes in treatment, the environment is becoming ever more competitive. Saint Philip's Hospital is among the largest non-profit hospitals in the nation…

Melanocytic Nevi Prevalence and the Relationship with Sun Exposure Among School Children

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Neslihan Şendur

2009-12-01

Full Text Available Background and Design: Melanocytic nevi (MN count is known as the strongest risk factor for melanoma development. So it is important to know the MN count in public. We aimed to determine the MN prevalence in schoolchildren and also clarify the possible relation between MN counts, constitutional variables and sun exposure. Material and Method: In this randomized, cross-sectional study, a questionnaire asking skin phenotypes and sun exposure in previous summer was prepared for primary-school children. Nine hundred and sixty questionnaires distributed to the parents. Children who were given permission by parents for examination were examined for whole body MN. Results: Questionnaires were answered by parents of 939 children and 622 children (316 boys and 306 girls were examined. Mean age of children was 8.8±1.5 (6-12. Mean MN count was 19.6±16.6 and this count was increasing with age (p<0.001. MN count was significantly related with sex, skin phototype and skin colour. More MN were found in boys (p<0.001, children with sun sensitive phototypes (p=0.03 and light skin colour (p<0.001. Time spent outside on midday in previous summer was not related with the MN count (p=0.35. Sunburns experienced in previous summer were not related with MN count (p=0.11. MN were most densely located on the face, and then on upper extremity, trunk and lower extremity in decreasing order. There were more MN on the more sun exposed sites of the arms, hands and feet. Conclusion: It was found that previous summer sun exposure had no effect on MN count in schoolchildren. However, relation between MN count and skin phenotype and distribution of the MN on the body suggest that sun exposure could affect MN count and this effect could be seen in a long period of time.

Coupling of tertiary and quaternary changes in human hemoglobin: A 1D and 2D NMR study of hemoglobin Saint Mande (βN102Y)

International Nuclear Information System (INIS)

Craescu, C.T.; Blouquit, Y.; Mispelter, J.

1990-01-01

Hemoglobin Saint Mande (βN102Y) is a low-affinity mutant with the substitution site situated in the quaternary-sensitive α 1 β 2 interface. In adult hemoglobin the Asn102β contributes to the stability of the liganded (R) state, forming a hydrogen bond with Asp94α. The quaternary and tertiary perturbations subsequent to the Tyr for Asn substitution in monocarboxylated hemoglobin Saint Mande have been investigated by one-and two-dimensional nuclear magnetic resonance (NMR) spectroscopy. Analysis of the one-dinensional NMR spectra of the liganded and unliganded samples in 1 H 2 O provides evidence that both R and T quaternary structures of Hb Saint Mande are different from the corresponding ones in HbA. In the monocarboxylated form of the mutant hemoglobin, at acid pH, the authors have observed the disappearance of an R-type hydrogen bond and the appearance of a new one whose proton resonates like a deoxy T marker. Using two-dimensional NMR methods and on the basis of previous results on the monocarboxylated HbA, they have obtained a significant number of resonance assignments in the spectra of monocarboxylated Hb Saint Mande at pH 5.6 in the presence or absence of a strong allosteric effector, inositol hexaphosphate. This enabled us to characterize the tertiary conformational changes triggered by the quaternary-state modification. The observed structural variations are confined within the heme pocket regions but concern both the α and β subunits

An annotated checklist of scale insects (Hemiptera: Coccoidea) of Saint Lucia, Lesser Antilles .

Science.gov (United States)

Malumphy, Chris

2014-07-31

An annotated list of 83 scale insect species (Hemiptera: Sterorrhyncha: Coccoidea) recorded from Saint Lucia is presented, based on data gathered from UK quarantine interceptions, samples collected in an urban coastal habitat in the North West of the Island in 2013, and published records. Thirty-three species (40%) are recorded for the first time for the country, including Dysmicoccus joannesiae (Costa Lima), a South American mealybug, and Poliaspoides formosana (Takahashi), an Asian armoured scale insect pest of bamboo, which are new for the Caribbean region. The economic, environmental and social impacts caused by introduced exotic species of scale insect are discussed. Two predatory midges Diadiplosis ?coccidivora (Felt) and Diadiplosis multifila (Felt) (Diptera: Cecidomyiidae) are recorded for the first time from Saint Lucia. The latter species was observed causing 90% mortality of a large infestation of passion vine mealybug Planococcus minor (Maskell) on soursop fruit. 

Parametric study of the low-enriched uranium integrated Fort-Saint-Vrain element; comparative evaluation with the interacting tubular element

International Nuclear Information System (INIS)

Cerles, J.M.; Carvallo, G.; Vallepin, C.

1971-11-01

This paper presents a study of the influence of the different geometric and neutronic parameters on the calculation of the cycle with low-enriched uranium in a Fort-Saint-Vrain type brick. The study is divided in two parts: a stage of physics, essentially neutronics; an economical part where the costs are taken into account. At the level of studies of neutronics and costs, a parallel comparison is developed between the brick Fort-Saint-Vrain and the interacting tubular element, and even thorium. 6 refs. 29 figs [fr

«O Sancta Haera». Pilgrims and Pilgrimage in the Sanctuary of Sainte Foy at Conques

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Marco Papasidero

2017-12-01

Full Text Available The Liber miraculorum Sancte Fidis, written during the XI century, partially by Bernard of Angers, describes miracles, healings and rituals practiced in the sanctuary of Sainte Foy at Conques, martyr of the beginning of the IV century.The Liber allows us to analyze the anthropological and religious dimension of the pilgrims and their pilgrimage. As a matter of fact, through the descriptions of the pilgrims, their gestures, their aspects, their words, their ritual practices by the tomb, their rich or poor offerings, we can analyze the dimension of the Medieval pilgrimage as a specific case study, which can help us describe the idea of pilgrimage in Medieval West Europe and specifically in this sanctuary.Furthermore, through the reading of the accounts of miracle stories, we can analyze the healing ritual practices, the miraculous dimension of this cult and the Sainte’s ability to treat diseases. The center of the Conques cult was – and remains – the Majesty of Sainte Foy, a reliquary statue in which the power (virtus/dynamis of the saint’s relics is concentrated.

Ludopathy and the employees at saint bonaventure university, Medellín branch, Colombia, 2010

OpenAIRE

Cano Bedoya, Victor Hugo; Universidad de San Buenaventura; Pérez Pérez, Jorge Arturo; Universidad de San Buenaventura, Medellín - Colombia

2010-01-01

This current article consists of a description of the use of game of chance and videogames, by the students, instructors, and employees at saint Bonaventure University, Medellin Branch and its relationship with both medical and psychological dimensions, which include variables like the following: concentration difficulties, change of mood, physical discomfort, preference of games to sports, and relaxed atmosphere as it is produced by games. In this true stage, the results with employees are s...

Field-level validation of a CLIMEX model for Cactoblastis cactorum (Lepidoptera: Pyralidae) using estimated larval growth rates.

Science.gov (United States)

Legaspi, Benjamin C; Legaspi, Jesusa Crisostomo

2010-04-01

Invasive pests, such as the cactus moth, Cactoblastis cactorum (Berg) (Lepidoptera: Pyralidae), have not reached equilibrium distributions and present unique opportunities to validate models by comparing predicted distributions with eventual realized geographic ranges. A CLIMEX model was developed for C. cactorum. Model validation was attempted at the global scale by comparing worldwide distribution against known occurrence records and at the field scale by comparing CLIMEX "growth indices" against field measurements of larval growth. Globally, CLIMEX predicted limited potential distribution in North America (from the Caribbean Islands to Florida, Texas, and Mexico), Africa (South Africa and parts of the eastern coast), southern India, parts of Southeast Asia, and the northeastern coast of Australia. Actual records indicate the moth has been found in the Caribbean (Antigua, Barbuda, Montserrat Saint Kitts and Nevis, Cayman Islands, and U.S. Virgin Islands), Cuba, Bahamas, Puerto Rico, southern Africa, Kenya, Mexico, and Australia. However, the model did not predict that distribution would extend from India to the west into Pakistan. In the United States, comparison of the predicted and actual distribution patterns suggests that the moth may be close to its predicted northern range along the Atlantic coast. Parts of Texas and most of Mexico may be vulnerable to geographic range expansion of C. cactorum. Larval growth rates in the field were estimated by measuring differences in head capsules and body lengths of larval cohorts at weekly intervals. Growth indices plotted against measures of larval growth rates compared poorly when CLIMEX was run using the default historical weather data. CLIMEX predicted a single period conducive to insect development, in contrast to the three generations observed in the field. Only time and more complete records will tell whether C. cactorum will extend its geographical distribution to regions predicted by the CLIMEX model. In terms

The first leg transplant for the treatment of a cancer by Saints Cosmas and Damian.

Science.gov (United States)

Androutsos, G; Diamantis, A; Vladimiros, L

2008-01-01

The most renowned of all medically inclined saints must have been St. Cosmas and St. Damian. They became the special patrons of surgery, due to their miraculous operations. On one occasion, they amputated a cancerous leg and replaced it with another, taken from a Moor who had just died. This dramatic cure was meat and drink for artists, and has been portrayed many times.

Further contributions to a new tectonic interpretation of the Sainte Victoire Mountain (Provence, France)

Energy Technology Data Exchange (ETDEWEB)

Ricour, J.; Monteau, R.; Laville, P.; Agryriadis, I.

2016-10-01

A new tectonic interpretation of the Sainte Victoire Mountain (north of Marseille, south eastern France) is proposed, principally invoking vertical movements and providing evidence which suggests an uplift which may be still active today in the western part. Some new observations confirm our hypothesis. (Author)

L’entre-soi élitaire à Saint-Barthélemy

NARCIS (Netherlands)

Cousin, B.; Chauvin, S.

2012-01-01

Après un siècle de dénuement, l’île antillaise de Saint-Barthélemy a connu un développement continu depuis sa « découverte » par la grande bourgeoisie américaine à la fin des années 1950. Centrées autour de la villégiature de luxe, les activités économiques de l’île ont nécessité le recours

Useful Brazilian plants listed in the field books of the French naturalist Auguste de Saint-Hilaire (1779-1853).

Science.gov (United States)

Brandão, Maria G L; Pignal, Marc; Romaniuc, Sergio; Grael, Cristiane F F; Fagg, Christopher W

2012-09-28

Information regarding the use of beneficial, native Brazilian plants was compiled by European naturalists in the 19th century. The French botanist Auguste de Saint-Hilaire (1779-1853) was one of the most important such naturalists; however, his manuscripts (field books) have not yet been studied, especially in the context of useful plants. To present data documented by Saint-Hilaire in his field book regarding the use of native plants by the Brazilians. Data on useful plants were obtained from field books (six volumes) deposited in the Muséum national d' Histoire naturelle in Paris, France. The vernacular names of the plants, registered as "N.V." or "Nom Vulg." in the field book, were carefully searched. Traditional information about these plants was translated and organised using a computer. The botanical identification of each plant was determined and updated from the original descriptions and names cited in the field books by A. de Saint-Hilaire. Correlated pharmacological studies were obtained from PubMed. A total of 283 useful plants were recorded from the field books and 165 (58.3%) could be identified to genus or species. Fifty-eight different traditional uses were registered for the identified plants; the most common were as purgatives and febrifuges. Other data recovered were related to edible fruits and plants with interesting sensorial characteristics. For the few species that have been subjected to laboratory studies, the efficacy of the recorded traditional uses was confirmed. The data recorded by the French naturalist A. de Saint-Hilaire represent a rich, unexplored source of information regarding the traditional uses of Brazilian plants. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

Interrater reliability of the Saint-Anne Dargassies Scale in assessing the neurological patterns of healthy preterm newborns

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Carla Ismirna Santos Alves

Full Text Available Abstract Objectives: to assess the interrater reliability of the Saint-Anne Dargassies Scale in assessing neurological patterns of healthy preterm newborns. Methods: twenty preterm newborns met the inclusion criteria for participation in this prospective study. The neurologic examination was performed using the Saint-Anne Dargassies Scale, showing normal serial cranial ultrasound examination. In order to test the reliability, the study was structured as follows: group I (rater 1/physiotherapist; rater 2/neonatologist; group II (rater 3/physiotherapist; rater 4/child neurologist and the gold standard (expert and professor in pediatric neurology. Results: high interrater agreement was observed between groups I - II compared with the gold standard in assessing postural pattern (p<0.01. Regarding the assessment ofprimitive reflexes, greater agreement was observed in the evaluation of palmar grasp reflex and Moro reflex (p< 0.01 for group I compared with the gold standard. An analysis of tone demonstrated heterogeneous agreement, without compromising the reliability of the scale. The probability of equality between measurements of head circumference in the two groups, compared with the gold standard, was observed. Conclusions: the Saint-Anne Dargassies Scale demonstrated high reliability and homogeneity with significant power of reproducibility and may be capable to identify preterm newborns suspected of having neurological deficits.

Baldrige Award cites two hospitals. Baptist, Saint Luke's hospitals honored for quality, performance.

Science.gov (United States)

Rees, Tom

2004-01-01

Baptist Hospital Inc., Pensacola, Fla.; and Saint Luke's Hospital, Kansas City, Mo., have received the prestigious Malcolm Baldrige National Quality Award in the category of healthcare. Named for a former secretary of commerce, the award recognizes efficiency, effectiveness and excellence. The two hospitals are among only seven companies in the U.S. to be so recognized this year.

Centro Federal de Comunidad Saint Louis - EE.UU.

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Hellmuth, George

1980-04-01

Full Text Available The Community Federal Center lies in the outskirts of the town of Saint Louis. It was conceived and designed by the project authors — in a style characteristic of them — as a suburban architectonic complex for office use. The work, standing out over an open stretch of land, has an ample base, with a volume that is neither the actual tower of the city centre nor the classic low rural construction. The building's architectonic language permits an integration, by sympathy, in the context of the neighbouring uni-family housing zone, without naturally being assimilated in them, due to the disparity of functions. It is achieved through a fracture of scaled volumes, breaking the classic coldness of the big office building, whilst at the same time thanks to its robustness, it indicates the activity housed inside.

El Community Federal Center está emplazado en las afueras de la ciudad de Saint Louis. Fue concebido y diseñado por los autores del proyecto —en un estilo que les es característico—, como un complejo arquitectónico suburbano destinado a oficinas. La obra, que se eleva sobre un terreno despejado, es amplía de base, presentando un volumen que no es ni la torre propia del centro urbano ni la clásica construcción rural de baja altura. El lenguaje arquitectónico del edificio permite una integración, por simpatía, en el contexto de la zona de viviendas unifamiliares cercana, sin llegar, naturalmente, a asimilarse a ellas dada la disparidad de funciones. Se lleva a cabo por medio de una fractura de volúmenes, escalonados, que rompen la frialdad clásica del gran edificio de oficinas, sin dejar de indicar, por su robustez, la actividad que alberga en su interior.

Motifs et manifestations de l’amour de l’homme pour Dieu et l’amour du prochain selon Saint Basile le Grand

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Ernest Janczyk

2017-04-01

Full Text Available This article addresses the issue of the motivation of the fundamental order of love for God and the neighbour which Saint Basil the Great used in his doctrine. Based on an analysis of the texts of Saint Basil, this article demonstrates the intimate relationship that should exist between the love for God and the love for man. The ideal of this relationship is represented, according to the analysis, by Jesus Christ, the only Saviour of the world.

Nuclear safety and radiation protection report of the Saint-Laurent-des-Eaux nuclear facilities - 2011

International Nuclear Information System (INIS)

2012-01-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the facilities of the Saint-Laurent-des-Eaux nuclear power plant (Saint-Laurent-Nouan (FR)): 2 partially dismantled graphite-gas reactors and a graphite sleeves storage silo (INB 46 and 74), and 2 PWR reactors in operation (INB 100). Then, the nuclear safety and radiation protection measures taken regarding the facilities are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2011, are reported as well as the radioactive and non-radioactive (chemical, thermal) effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facilities are presented and sorted by type of waste, quantities and type of conditioning. Other environmental impacts (noise, microbial proliferation in cooling towers) are presented with their mitigation measures. Actions in favour of transparency and public information are presented as well. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

Nuclear safety and radiation protection report of the Saint-Laurent-des-Eaux nuclear facilities - 2010

International Nuclear Information System (INIS)

2011-06-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the facilities of the Saint-Laurent-des-Eaux nuclear power plant (Saint-Laurent-Nouan (FR)): 2 partially dismantled graphite-gas reactors and a graphite sleeves storage silo (INB 46 and 74), and 2 PWR reactors in operation (INB 100). Then, the nuclear safety and radiation protection measures taken regarding the facilities are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, are reported as well as the radioactive and non-radioactive (chemical, thermal) effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facilities are presented and sorted by type of waste, quantities and type of conditioning. Other environmental impacts (noise, microbial proliferation in cooling towers) are presented with their mitigation measures. Actions in favour of transparency and public information are presented as well. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

A comparative study of proliferative nodules and lethal melanomas in congenital nevi from children.

Science.gov (United States)

Yélamos, Oriol; Arva, Nicoleta C; Obregon, Roxana; Yazdan, Pedram; Wagner, Annette; Guitart, Joan; Gerami, Pedram

2015-03-01

Differentiating proliferative nodules (PNs) from melanomas arising in congenital nevi (CN) is a considerable challenge for dermatopathologists. Most of the specimens dermatopathologists assess that deal with this differential diagnosis involve proliferations of melanocytes arising in the dermis. In this study, we compare the clinical, histologic, and molecular findings of these 2 conditions. In our database, we found 22 examples of PNs arising in the dermis of CN and 2 cases of lethal melanomas arising from the dermis/epidermis of CN of children. Importantly, we found that among dermal melanocytic proliferations arising from CN in children, PNs are far more common than lethal melanomas. Clinically, multiplicity of lesions favored a diagnosis of PNs, whereas ulceration was infrequent in PNs compared with lethal melanomas. Histologically, PNs showed several distinct patterns including expansile nodules of epithelioid melanocytes with mitotic counts lower than that seen in the melanomas (1.67 vs. 12.5 mitoses/mm), a small round blue cell pattern often highly mitotically active, neurocristic-like, blue nevus-like, a nevoid melanoma-like pattern, or an undifferentiated spindle cell pattern. The lethal melanomas both featured expansile nodules of epithelioid melanocytes with high mitotic counts (range, 5 to 20 mitoses/mm) and an ulcerated overlying epidermis. At the molecular level, the PNs showed mostly whole chromosomal copy number aberrations, which in some cases were accompanied by rare partial chromosomal aberrations, whereas both lethal melanomas showed highly elevated copy number aberrations involving 6p25 without gains of the long arm of chromosome 6.

A reactivity accidents simulation of the Fort Saint Vrain HTGR

International Nuclear Information System (INIS)

Fainer, Gerson

1980-01-01

A reactivity accidents analysis of the Fort Saint Vrain HTGR was made. The following accidents were analysed 1) A rod pair withdrawal accident during normal operation, 2) A rod pair ejection accident, 3) A rod pair withdrawal accident during startup operations at source levels and 4) Multiple rod pair withdrawal accident. All the simulations were performed by using the BLOOST-6 nuclear code The steady state reactor operation results obtained with the code were consistent with the design reactor data. The numerical analysis showed that all accidents - except the first one - cause particle failure. (author)

Ciguatera fish poisoning in an international ship crew in Saint John Canada: 2015.

Science.gov (United States)

Muecke, C; Hamper, L; Skinner, A L; Osborne, C

2015-11-05

An international ship crew presented for medical care in Saint John, New Brunswick, following rapid onset of gastrointestinal and in some cases neurological and cardiac symptoms after a common fish meal. Ciguatera poisoning was identified as the cause of illness. This report describes the public health investigation and management of this incident, including collaboration between the implicated provincial and federal authorities.

High-rise construction in the Saint Petersburg agglomeration in 1703-1950s

Science.gov (United States)

Sementsov, Sergey; Akulova, Nadezhda; Kurakina, Severina

2018-03-01

Regularities of high-rise construction (implemented projects and developments) in Saint Petersburg and the Saint Petersburg agglomeration since the foundation of the city in 1703 till the 1950s are considered. Based on these regularities, a single spatially developed system of vertical dominants is formed. High-rise construction in the city and its suburbs started in the 1710s and continues up to the present time. In the considered decades (1703-1950s), high-rise construction mostly performed urban-planning functions (with vertical and symbolic dominants), relying on patterns of the visual perception of man-made landscapes under development. Since the 1710s, the construction of vertical dominants (mainly temples, spires of towers, lighthouses, etc.) of five ranks (depending on the altitude range and in relation to the background development) was conducted in territories of the entire agglomeration. These dominants were arranged in landscapes of the city and suburbs with almost mathematically precise accuracy and according to special regulations. Such dominants obtained particular descriptive and silhouette characteristics in accordance with the conditions of spatial perception. In some periods of city development, attempts were made to create monuments (symbolic dominants) of specific height and include those in the spatial system of high-rise dominants as significant elements of the city silhouette.

A second level of the Saint Petersburg skyline

Science.gov (United States)

Krasnopolsky, Andrey; Bolotin, Sergey

2018-03-01

The article considers the history of the residential development in Saint Petersburg and states corresponding landmark dates. In recent years, changes in the altitude range of the residential development are noted, the influence of this factor on the formation of the city's silhouette is assessed. Reasons for such changes are identified. Attractiveness of high-rise residential complexes for living is assessed. Conclusions are made of tendencies in further housing construction development in terms of its altitude range. It is noted that it is possible to locate multi-storied buildings in the periphery of the city, taking into account specific visual characteristics of the construction site and silhouette of erected buildings; as for central districts, strict regulations regarding the altitude range are needed.

Geothermic and thermal drilling in Saint-Paul-les-Dax - SPDX 1

Energy Technology Data Exchange (ETDEWEB)

Godard, J.M.; Tronel, F.; Penicault, J.P.; Pouchan, P.

1994-12-31

In 1990, the municipality of Saint Paul les Dax (Landes), located in a thermal area, has decided to promote a geothermal-balneotherapy continued project. Geological studies and seismic exploration from oil and gas allowed to decide to drill a deep well on the northern flank of Dax diapir. The drilling operation (October - December 1993) has given the following result : final depth 1665 m, thermal reservoir dated Danian-Paleocene producing water at 66 degree celsius. The potential flowrate estimated at 150 m{sup 3}/h is going to be used to met the heating requirements of public buildings, greenhouses, collective equipment and new thermal centers. The geothermal use of the water will give annual energy saving of 5 900 MWh. (Authors). 2 figs.

The 1.3-m Robotically Controlled Telescope (RCT) at Kitt Peak - A Fifty year old dream Realized: Telescope Characteristics, Current Research and Education Progr

Science.gov (United States)

Guinan, Edward; Gelderman, Richard; Strolger, Louis-Gregory; Carini, Michael T.; McGruder, Charles, III; Campbell, Rachel; Walter, Donald K.; Davis, Donald R.; Tedesco, Edward F.; Engle, Scott G.

2011-03-01

The 1.3 m Robotically Controlled Telescope (RCT) on Kitt Peak has a rich history, including its role as a prototype for remotely controlled telescopes during the 1960s. As such, the RCT could be considered one of the first - Telescopes from Afar. The telescope, originally called the Remotely Controlled Telescope, has been renamed the Robotically Controlled Telescope to reflect the change in operational control and mode of use. The RCT was a conceptual precursor of today's robotic telescopes, but the actual operation of a remotely controlled telescope was technologically premature for its time, and was subsequently manually operated primarily to conduct optical and infrared observations as well being used as a test bed for new spectroscopic and photometric instruments. In 1995 budget constraints forced the closing of the telescope as part of the Kitt Peak National Observatory (KPNO), following nearly 30 years of distinguished service to KPNO. A request for proposals to operate this telescope was issued to the science community. The RCT consortium, lead by Western Kentucky University, was the successful proposer for operation of the telescope. After several difficult years of retrofitting, refurbishing, and automating the telecope and observatory dome, the telescope has returned to routine science operations in November 2009. The RCT has operated smoothly since that time, with no major interruptions. Observations of objects of interest to the consortium partners (including: comets & asteroids, variable & binary stars, exoplanets, supernovae, quasars & blazars) are being routinely obtained and evaluated. One of the distinguishing features of the RCT is that it is an autonomous observatory designed to handle diverse optical imaging and photometry programs. These include being able to automatically deal with a wide range of observing parameters such as -integration time, sky conditions, repetitions, return visits, filters, air mass, non-sidereal objects, transients etc

Inhibition of Corneal Neovascularization with the Combination of Bevacizumab and Plasmid Pigment Epithelium-Derived Factor-Synthetic Amphiphile INTeraction-18 (p-PEDF-SAINT-18 Vector in a Rat Corneal Experimental Angiogenesis Model

Directory of Open Access Journals (Sweden)

Ching-Hsein Chen

2013-04-01

Full Text Available Bevacizumab, a 149-kDa protein, is a recombinant humanized monoclonal antibody to VEGF. PEDF, a 50-kDa glycoprotein, has demonstrated anti-vasopermeability properties. In this study, we demonstrated that the combination of bevacizumab and plasmid pigment epithelium-derived factor-synthetic amphiphile INTeraction-18 (p-PEDF-SAINT-18 has a favorable antiangiogenic effect on corneal NV. Four groups (Group A: 0 μg + 0 μg, B: 0.1 μg + 0.1 μg, C: 1 μg + 1 μg, and D: 10 μg + 10 μg of bevacizumab + p-PEDF-SAINT-18 were prepared and implanted into the rat subconjunctival substantia propria 1.5 mm from the limbus on the temporal side. Then, 1 μg of p-bFGF-SAINT-18 was prepared and implanted into the rat corneal stroma 1.5 mm from the limbus on the same side. The inhibition of NV was observed and quantified from days 1 to 60. Biomicroscopic examination, western blot analysis and immunohistochemistry were used to analyze the 18-kDa bFGF, 50-kDa PEDF and VEGF protein expression. No inhibition activity for normal limbal vessels was noted. Subconjunctival injection with the combination of bevacizumab and p-PEDF-SAINT-18 successfully inhibited corneal NV. The bFGF and PEDF genes were successfully expressed as shown by western blot analysis, and a mild immune response to HLA-DR was shown by immunohistochemistry. We concluded that the combination of bevacizumab and p-PEDF-SAINT-18 may have more potent and prolonged antiangiogenic effects, making it possible to reduce the frequency of subconjunctival.Bevacizumab, a 149-kDa protein, is a recombinant humanized monoclonalantibody to VEGF. PEDF, a 50-kDa glycoprotein, has demonstrated anti-vasopermeabilityproperties. In this study, we demonstrated that the combination of bevacizumaband plasmid pigment epithelium-derived factor-synthetic amphiphile INTeraction-18(p-PEDF-SAINT-18 has a favorable antiangiogenic effect on corneal NV. Four groups(Group A: 0 μg + 0 μg, B: 0.1 μg + 0.1 μg, C: 1 μg + 1 μg, and

Identifying Key Stakeholder Groups for Implementing a Place Branding Policy in Saint Petersburg

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Kulibanova V. V.

2017-10-01

Full Text Available Regional brands have become a valuable intangible asset and a crucial competitive resource for forging partnerships. An effective place branding policy is impossible without a precise understanding of the interests of stakeholder groups. It is essential to realize that each region is unique in its own way. Territories differ in the structure of stakeholders, their influence on regional development, and the range of leverages over regional decision-makers. This study aims to give a more precise definition of key groups of stakeholders in Saint Petersburg place branding, and to identify them. The authors employ the method of theoretical and empirical typology of a territory’s stakeholders within a theoretical framework proposed by E. Freeman, P. Kotler, S. Zenker, and E. Brown. The article defines the concept of key regional stakeholders and identifies them. The proposed target audience (stakeholder group model for a place branding policy is tested on the case of Saint Petersburg. The authors show that each target audience of place marketing requires an individual policy. This is explained by the fact that each group enjoys its unique features that should be taken into account when creating and transmitting messages.

La estructura del poder en la "Mémoires" de Saint-Simon

OpenAIRE

Robles Vázquez, Carmen

2004-01-01

Análisis de las diferentes formas en que Saint-Simon presenta en sus Memorias el poder, y de qué manera se manifiesta éste en sus aspectos económicos, políticos, religiosos, familiares y sociales, tanto durante los últimos años del reinado de Luis XIV como durante la regencia de Felipe de Orleáns en una sociedad teocrática y absolutista, fuertemente jerarquizada, característica del Antiguo Régimen.

Distribution of some organochloride pesticides in the All Saints Bay, Bahia, Brazil

International Nuclear Information System (INIS)

Beretta, M.; Costa, M.A.; Tavares, T.M.

1999-01-01

First restrictions to organochlorine insecticides (OC) in Brazil date of 1976 and by 1985 they were completely prohibited. However use of existing stocks and smuggled parcels as well as official use in malaria campaigns still takes place. During the SH summer of 1995 a cross-sectional survey was conducted for organochloride pesticides in 12 intertidal sites, both in sediments and in some selected edible species of the All Saints Bay, east of Brazil

Sainte-Bernardette du Banlay, Nevers

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Christophe Joly

2009-11-01

Full Text Available Construite par Claude Parent et Paul Virilio en 1964-1965, l’église Sainte-Bernadette du Banlay témoigne de leurs travaux sur la fonction oblique. L’édifice fut édifié à l’issue d’un concours d’architecture lancé en 1963 par Mgr Vial et l’Abbé Bourgoin, curé de la paroisse. L’église est inspirée de l’architecture des bunkers. Deux coques de béton s’imbriquent l’une dans l’autre en se décalant par rapport à l’axe longitudinal. L’apparence générale est un édifice monolithique, qui évoque un rocher. Á l’intérieur, deux grands plans obliques paraissent exhumés pour constituer la nef et le chœur. En relation étroite avec la grotte des apparitions de Lourdes, l’église est construite comme une crypte suspendue dont la coupe adopte la forme d’un cœur. Par le choix de matériaux bruts et d’un éclairage zénithal, les architectes confèrent à l’ensemble une étonnante intimité. C’est par l’opposition entre le volume extérieur austère et fermé et l’espace intérieur accueillant et protecteur que les concepteurs expriment la nouvelle fonction d’une église conçue dans une période d’incertitude et de tensions.The Sainte-Bernadette du Banlay church at Nevers was built from 1964 to 1965 to the designs of the architects Claude Parent and Paul Virilio, working on their theme of the oblique function. It was the fruit of an architectural competition organised in 1963 by Monseigneur Vial and the Abbé Bourgoin, the parish priest. The church’s architecture is inspired by that of defensive bunkers. Two reinforced concrete shells are joined the one into the other but out of true on a longitudinal axis. The overall appearance of the church is that of a monolithic block, something like a rock. Inside, two large oblique planes seem to emerge to create the nave and the chancel. Closely related to the Lourdes grotto of the Virgin’s appearances, the church is designed as a suspended crypt

The introduction of Melanoides tuberculata (Mollusca: Thiaridae) to the island of Saint Lucia (West Indies) and its role in the decline of Biomphalaria glabrata, the snail intermediate host of Schistosoma mansoni.

Science.gov (United States)

Pointier, J P

1993-06-01

A malacological survey was carried out in May 1992 in the whole hydrographic system of Saint Lucia 11 years after the end of a biological control programme to eliminate Biomphalaria glabrata, the snail intermediate host of Schistosoma mansoni. A competitor snail, Melanoides tuberculata, was introduced to Saint Lucia in 1978 and field experiments in several habitats were conducted by Prentice between 1978 and 1986. At the present time M. tuberculata is the most common freshwater snail in Saint Lucia. The results of the survey, undertaken in sites where B. glabrata occurred in large populations in the past showed (i) the absence of the snail hosts from seven sites now extensively colonized by the competitor (ii) the presence of B. glabrata in low or very low densities in 17 sites together with the competitor and (iii) the presence of the intermediate hosts in large populations in only two sites where M. tuberculata was absent. These results confirm the positive results observed by Prentice. The presence of another planorbid snail, B. straminea, is reported for the first time in Saint Lucia.

La théorie de la diplomatie dans le Saint Empire Romain

OpenAIRE

Weber, Wolfgang E. J.

2016-01-01

Principes Dans ce que l’on nomme officiellement, depuis 1500 environ jusqu’à sa fin en 1806, le Saint Empire romain de la nation allemande (Heiliges Römisches Reich Deutscher Nation), le développement de la théorie de la diplomatie, autrement dit de conceptions relatives aux diplomates et à la diplomatie, est le fait d’élites soucieuses de mieux comprendre des problèmes posé...

Les carbonates néogènes de Sainte Croix (Iles Vierges. Etude stratigraphique et pétrophysique Neogene Carbonates At Saint Croix, Virgin Islands. Stratigraphic and Petrophysical Study

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Andreieff P.

2006-11-01

Full Text Available Un échantillonnage systématique des principaux affleurements des séries carbonatées néogènes de Sainte Croix (Iles Vierges a permis de préciser leur extension stratigraphique. C'est ainsi que la section-type de la formation Kingshill, qui avait été récemment attribuée au Miocène supérieur, est désormais datée du Miocène moyen d'après son riche contenu faunistique en foraminifères planctoniques et nannofossiles calcaires. Les diverses mesures pétrophysiques effectuées dans des niveaux d'environnement de dépôts différents (plate-forme, pente, bassin tendent à prouver que de bonnes porosités et perméabilités, donc de bons réservoirs, pourraient être trouvées dans des séries de pentes ou de fond de bassins associés à des plates-formes carbonatées. Systematic sampling of the main outcrops of Neogene carbonate series on Saint Croix, Virgin Islands, has enabled their stratigraphic extension to be determined. In this way, the Kingshill formation type section, which has recently been attributed to the late Miocene, is henceforth dated from the middle Miocene according to planktonic foraminifers and calcareous nannofossils. The different petrophysical measurements made in strata originated from different depositional environments (shelf, slope, basin tend to prove that good porosities and permeabilities, hence good reservoirs, might be found in slope or basin-bottom series associated with carbonate banks.

Training needs assessment of health care professionals in a developing country: the example of Saint Lucia.

Science.gov (United States)

Gaspard, Janice; Yang, Che-Ming

2016-04-16

Continuing education (CE) is crucial for quality improvement in health care. The needs assessment of CE helps ensure effectiveness. However, such an assessment necessitates certain techniques that are unfamiliar to health care communities in developing countries. This study identifies the needs of providing CE to health care personnel in Saint Lucia. This study was designed as a questionnaire survey to investigate the demographics, training needs, and preferred approaches to improve performance of the target population. The study population included the health care professionals of major public health care facilities in Saint Lucia. We used the World Health Organization-adopted Hennessy Hicks Training Needs Analysis Questionnaire, a self-reported close-ended structured questionnaire with a core set of 30 items. These items refer to tasks that are central to the role of health care professionals and are categorized into six superordinate categories: research/audit, communication/teamwork, clinical skills, administrative, managerial/supervisory, and continuing professional education. In total, 208 questionnaires were distributed; the response rate was 66.8%, and most respondents were nurses. The need for continuing professional education was rated the highest priority, followed by research/audit activities. The evidence suggests that most respondents required training in communication skills, management, clinical skills, and research methods. Providing training according to the needs is vital, particularly in developing countries. The present research methodology and findings offer perspectives on how to conduct needs assessment and offer reference points for developing countries whose background and health care environment are similar to those of Saint Lucia.

Levels of insecticide resistance to deltamethrin, malathion, and temephos, and associated mechanisms in Aedes aegypti mosquitoes from the Guadeloupe and Saint Martin islands (French West Indies).

Science.gov (United States)

Goindin, Daniella; Delannay, Christelle; Gelasse, Andric; Ramdini, Cédric; Gaude, Thierry; Faucon, Frédéric; David, Jean-Philippe; Gustave, Joël; Vega-Rua, Anubis; Fouque, Florence

2017-02-10

In the Guadeloupe and Saint Martin islands, Aedes aegypti mosquitoes are the only recognized vectors of dengue, chikungunya, and Zika viruses. For around 40 years, malathion was used as a mosquito adulticide and temephos as a larvicide. Since the European Union banned the use of these two insecticide molecules in the first decade of the 21st century, deltamethrin and Bacillus thuringiensis var. israelensis are the remaining adulticide and larvicide, respectively, used in Guadeloupe. In order to improve the management of vector control activities in Guadeloupe and Saint Martin, we investigated Ae. aegypti resistance to and mechanisms associated with deltamethrin, malathion, and temephos. Ae. aegypti mosquitoes were collected from six different localities of Guadeloupe and Saint Martin. Larvae were used for malathion and temephos bioassays, and adult mosquitoes for deltamethrin bioassays, following World Health Organization recommendations. Knockdown resistance (Kdr) genotyping for V1016I and F1534C mutations, and expression levels of eight enzymes involved in detoxification mechanisms were examined in comparison with the susceptible reference Bora Bora strain. Resistance ratios (RR 50 ) calculated for Ae. aegypti larvae showed high resistance levels to temephos (from 8.9 to 33.1-fold) and low resistance levels to malathion (from 1.7 to 4.4-fold). Adult females displayed moderate resistance levels to deltamethrin regarding the time necessary to affect 50% of individuals, varying from 8.0 to 28.1-fold. Molecular investigations on adult mosquitoes showed high resistant allele frequencies for V1016I and F1534C (from 85 to 96% and from 90 to 98%, respectively), as well as an overexpression of the glutathione S-transferase gene, GSTe2, the carboxylesterase CCEae3a, and the cytochrome genes 014614, CYP6BB2, CYP6M11, and CYP9J23. Ae. aegypti populations from Guadeloupe and Saint Martin exhibit multiple resistance to organophosphates (temephos and malathion), and

Convenio de contratación para el proyecto de la iglesia Saint-Pierre de Firminy-Vert

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Merwan Chaverra Suárez

2010-12-01

Full Text Available Los pormenores del proceso de contratación para el encargo de la iglesia Saint-Pierre de Firminy-Vert, entre 1960 y 1963, corresponde al desglose de las conversaciones e intercambios de correspondencia entre el arquitecto y sus clientes, que dieron lugar a un número de versiones y variantes del proyecto, así como a dificultades administrativas y económicas, que se prolongaron en el tiempo, hasta la firma del contrato. El proyecto de la iglesia Saint-Pierre de Firminy-Vert cuenta con un dossier completo, guardado y archivado en la Fundación Le Corbusier, que garantiza poder efectuar un análisis total del proyecto, enfocándolo en una metodología que posibilite el entendimiento y la reconstrucción de los hechos a partir de las fuentes primarias.

An Approach to Determine the Weibull Parameters and Wind Power Analysis of Saint Martin’s Island, Bangladesh

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Islam Khandaker Dahirul

2016-01-01

Full Text Available This paper explores wind speed distribution using Weibull probability distribution and Rayleigh distribution methods that are proven to provide accurate and efficient estimation of energy output in terms of wind energy conversion systems. Two parameters of Weibull (shape and scale parameters k and c respectively and scale parameter of Rayleigh distribution have been determined based on hourly time-series wind speed data recorded from October 2014 to October 2015 at Saint Martin’s island, Bangladesh. This research has been carried out to examine three numerical methods namely Graphical Method (GM, Empirical Method (EM, Energy Pattern Factor method (EPF to estimate Weibull parameters. Also, Rayleigh distribution method has been analyzed throughout the study. The results in the research revealed that the Graphical method followed by Empirical method and Energy Pattern Factor method were the most accurate and efficient way for determining the value of k and c to approximate wind speed distribution in terms of estimating power error. Rayleigh distribution gives the most power error in the research. Potential for wind energy development in Saint Martin’s island, Bangladesh as found from the data analysis has been explained in this paper.

Geographic distribution of ebony leaf monkey Trachypithecus auratus (E. Geoffroy Saint-Hilaire, 1812) (Mammalia: Primates: Cercopithecidae)

NARCIS (Netherlands)

Nijman, Vincent

2000-01-01

As one of the fundamental units of ecology and biogeography, the geographic distribution of the endemic and threatened ebony leaf monkey Trachypithecus auratus (E. Geoffroy Saint-Hilaire, 1812) on the islands of Java, Bali, and Lombok (Indonesia) has been assessed. All localities where the species

Expression of microphthalmia transcription factor, S100 protein, and HMB-45 in malignant melanoma and pigmented nevi.

Science.gov (United States)

Xia, Jianxin; Wang, Yanlong; Li, Fuqiu; Wang, Jinfeng; Mu, Yan; Mei, Xianglin; Li, Xue; Zhu, Wenjing; Jin, Xianhua; Yu, Kai

2016-09-01

Malignant melanoma (MM) is a type of malignant tumor, which originates from neural crest melanocytes. MM progresses rapidly and results in a high mortality rate. The present study aims to investigate the expression of microphthalmia transcription factor (MITF), the S100 protein, and HMB-45 in MM and pigmented nevi. A total of 32 MM samples (including three skin metastasis, three lymph node metastasis and two spindle cell MM samples), two Spitz nevus samples, four pigmented nevus samples and two blue nevus samples were collected. The expression levels of S100 protein, HMB-45, and MITF were observed via immunostaining. The S100 protein exhibited high positive rates in MM and pigment disorders (96.7 and 100%, respectively), but with low specificity. The S100 protein was also expressed in fibroblasts, myoepithelial cells, histocytes and Langerhans cells in normal skin samples. HMB-45 had high specificity. Its positive expression was only confined to MM cells and junctional nevus cells. Furthermore, HMB-45 was not expressed in melanocytes in the normal tissue samples around the tumor or in the benign intradermal nevus cells. MITF exhibited high specificity and high sensitivity. It was expressed in the nuclei of melanocytes, MM cells and nevus cells. It was observed to be strongly expressed in metastatic MM and spindle cell MMs. Thus, MITF may present as a specific immunomarker for the diagnosis and differential diagnosis of MM.

Whose Knowledge, Whose Values? The Contribution of Local Knowledge to Education Policy Processes: A Case Study of Research Development Initiatives in the Small State of Saint Lucia

Science.gov (United States)

Holmes, Keith; Crossley, Michael

2004-01-01

This paper draws upon a case study of education in the small Caribbean state of Saint Lucia (population 154,000) to examine how local knowledge and values can influence the education policy process. It is argued that recent research development initiatives have strengthened the ability of Saint Lucia to mediate international education agendas to…

Multiple sclerosis in Latter Day Saints (Mormons).

Science.gov (United States)

Hawkes, C H; Ramkumar, N; Baker, R; Lyon, J L

2007-04-01

Compliant members of the Church of Jesus Christ of Latter Day Saints (LDS, Mormons) have a low incidence of heart and lung disease that may relate to their healthy life style. We wished to determine whether multiple sclerosis (MS) was less frequent in this religious body. To ascertain this, diagnostic and treatment coding records were accessed from the Deseret Mutual Benefit Administrators (DMBA) for the 6 year period 1997-2002. DMBA is a medical insurance company that provides medical insurance to all employees of LDS Church in the US. This information was combined with prescribing records for disease modifying treatment, principally beta-interferon and Copaxone which are medications specific to MS. Using various search strategies we derived an approximate MS prevalence of 45-64/100,000. Comparison with MS rates from Utah and other states of comparable latitude suggest that strict LDS have an MS prevalence that is lower than expected and may reflect their healthy life style.

High-rise construction in the Saint Petersburg agglomeration in 1703–1950s

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Sementsov Sergey

2018-01-01

Full Text Available Regularities of high-rise construction (implemented projects and developments in Saint Petersburg and the Saint Petersburg agglomeration since the foundation of the city in 1703 till the 1950s are considered. Based on these regularities, a single spatially developed system of vertical dominants is formed. High-rise construction in the city and its suburbs started in the 1710s and continues up to the present time. In the considered decades (1703–1950s, high-rise construction mostly performed urban-planning functions (with vertical and symbolic dominants, relying on patterns of the visual perception of man-made landscapes under development. Since the 1710s, the construction of vertical dominants (mainly temples, spires of towers, lighthouses, etc. of five ranks (depending on the altitude range and in relation to the background development was conducted in territories of the entire agglomeration. These dominants were arranged in landscapes of the city and suburbs with almost mathematically precise accuracy and according to special regulations. Such dominants obtained particular descriptive and silhouette characteristics in accordance with the conditions of spatial perception. In some periods of city development, attempts were made to create monuments (symbolic dominants of specific height and include those in the spatial system of high-rise dominants as significant elements of the city silhouette.

Mount Saint Helens, Washington, USA, SRTM Perspective: Shaded Relief and Colored Height

Science.gov (United States)

2004-01-01

Mount Saint Helens is a prime example of how Earth's topographic form can greatly change even within our lifetimes. The mountain is one of several prominent volcanoes of the Cascade Range that stretches from British Columbia, Canada, southward through Washington, Oregon, and into northern California. Mount Adams (left background) and Mount Hood (right background) are also seen in this view, which was created entirely from elevation data produced by the Shuttle Radar Topography Mission. Prior to 1980, Mount Saint Helens had a shape roughly similar to other Cascade peaks, a tall, bold, irregular conic form that rose to 2950 meters (9677 feet). However, the explosive eruption of May 18, 1980, caused the upper 400 meters (1300 feet) of the mountain to collapse, slide, and spread northward, covering much of the adjacent terrain (lower left), leaving a crater atop the greatly shortened mountain. Subsequent eruptions built a volcanic dome within the crater, and the high rainfall of this area lead to substantial erosion of the poorly consolidated landslide material. Eruptions at Mount Saint Helens subsided in 1986, but renewed volcanic activity here and at other Cascade volcanoes is inevitable. Predicting such eruptions still presents challenges, but migration of magma within these volcanoes often produces distinctive seismic activity and minor but measurable topographic changes that can give warning of a potential eruption. Three visualization methods were combined to produce this image: shading of topographic slopes, color coding of topographic height, and then projection into a perspective view. The shade image was derived by computing topographic slope in the northeast-southwest (left to right) direction, so that northeast slopes appear bright and southwest slopes appear dark. Color coding is directly related to topographic height, with green at the lower elevations, rising through yellow and tan, to white at the highest elevations. The perspective view simulates the

“State of the Estuary” - Developing a long term monitoring, assessment and reporting framework for the lower Saint Louis River

Science.gov (United States)

As the lower Saint Louis River moves closer and closer to delisting as an Area of Concern, it is incumbent that we measure, assess and report on our success. Going forward, It’s equally important that we continue monitoring to protect and sustain the healthy ecosystems we&...

PREFACE: 2nd International School and Conference Saint-Petersburg OPEN on Optoelectronics, Photonics, Engineering and Nanostructures (SPbOPEN2015)

Science.gov (United States)

2015-11-01

The 2nd International School and Conference ''Saint Petersburg OPEN 2015'' on Optoelectronics, Photonics, Engineering and Nanostructures was held on April 6 - 8, 2015 at St. Petersburg Academic University. The School and Conference included a series of invited talks given by leading professors with the aim to introduce young scientists with actual problems and major advances in physics and technology. The keynote speakers were Mikhail V. Maximov (Ioffe Physico-Technical Institute RAS, Russia) Vladimir G. Dubrovskii (St. Petersburg Academic University and St. Petersburg State University, Russia) Anton Yu. Egorov (JSC Connector Optics, Russia) Victor V. Luchinin (St. Petersburg State Electrotechnical University, Russia) Vladislav E. Bugrov (St. Petersburg University of Internet Technologies, Mechanics and Optics, Russia) Vitali A. Schukin (VI Systems, Germany) Yuri P. Svirko (University of Eastern Finland, Finland) During the poster session all undergraduate and graduate students attending the conference presented their works. A sufficiently large number of participants, with more than 170 student attendees from all over the world, allowed the Conference to provide a fertile ground for fruitful discussions between the young scientists as well as to become a perfect platform for valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers basing on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year ''Saint Petersburg OPEN 2015'' is organized by St. Petersburg Academic University in cooperation with Peter the Great St. Petersburg Polytechnic University. The School and Conference is supported by Russian Science Foundation, SPIE (The International Society for Optics and Photonics), OSA (The Optical Society) and by Skolkovo Foundation. It is a continuation of the annual schools and seminars for

Center for Transportation Studies 24th annual transportation research conference, May 22-23, 2013, Saint Paul, Minnesota.

Science.gov (United States)

2013-05-01

The University of Minnesotas Center for Transportation : Studies is pleased to present its 24th Annual Transportation : Research Conference, May 22-23, 2013. The conference will : be held at the Saint Paul RiverCentre, 175 West Kellogg : Boulevard...

City’s lost jewel. History of Cracow’a All Saints church till the end of XVI century

Directory of Open Access Journals (Sweden)

Katarzyna Walczak

2013-12-01

Full Text Available One of the oldest churches in Krakow, dedicated to All Saints, was situated between Grodzka and Franciszkańska Street. It was build in the XIII century, could had been replacement church for first Cracow’s parish, which was transferred from Saint Trinity church. The name of All Saints church was mentioned for the first time in Vita S. Stanislai. The second time in 1278 his rector Arnold was noted. Most interesting fact is that in the Tables of Pence from 1325–1327 you can find two rectors, who had separate salary and were called rectors of wooden and brick churches. In 1490 church got a collegiate title. Than double rectory was liquidated and positions of provost and dean were established. Church was a place where Brotherhood of the Poor created by Bishop Zbigniew Oleśnicki used to work. Our knowledge of churches looks comes from iconography which was made when the building was already a ruin. According to those sources church had two naves, was oriented and had simply completed presbytery. The building had adhered tower, sacristy, treasure and chapel, called capella antiqua. Description of the interior of the church comes from 1599, when Jerzy Radziwiłł, Bishop of Cracow had visited it. According to the decision of the City Beautification Committee, the church was demolished in 1835, and church’s equipment was sold on auction. The tower survived till 1840, when it shared the fate of the rest of the building.

Evolution of high-rise construction in Leningrad - Saint Petersburg in the middle of the 20th - Early 21st centuries: projects and Implementation

Science.gov (United States)

Vaytens, Andrey; Rusanov, Gennadiy; Skryabin, Pavel

2018-03-01

One of the most important issues in national urban planning is arrangement of high-rise buildings in the largest cities of Russia. This issue becomes especially acute in such cities as Saint Petersburg, which has unique architectural and urban-planning heritage preserved to a great extent. In this regard, it seems important to trace the evolution of high-rise construction development and arrangement in Leningrad - Saint Petersburg in the middle of the 20th — early 21st centuries. The goal of the article is to consider high-rise construction development regarding both public and residential buildings in comparison of project ideas and results of their implementation in the 1940s-2000s. Prerequisites and issues of high-rise construction of that period are considered. Particular attention is paid to changes in the official urban-planning policy, regulatory framework and attitude of city authorities to high-rise construction. The study was carried out with the consideration of the following historic periods differing in their urban-planning policy: the late 1940s-1950s; 1960s; 1970-1980s; 1990s; 2000s-2010s. Economical prerequisites of high-rise construction and their influence on the modern urban-planning policy during the post-Soviet period are considered. In conclusion, an attempt is made to determine tendencies of high-rise construction development in Saint Petersburg.

The Veneration and Visitation of the Graves of Saints in Soviet Central Asia. Insights from the Southern Ferghana Valley, Uzbekistan

Czech Academy of Sciences Publication Activity Database

Exnerová, Věra

2015-01-01

Roč. 83, č. 3 (2015), s. 501-536 ISSN 0044-8699 R&D Projects: GA ČR(CZ) GA14-16520S Institutional support: RVO:68378009 Keywords : graves of saints * Uzbekistan * Ferghana Valley * Soviet period * oral history * local practices Subject RIV: AB - History

Nutrient Status and Criteria Development for the Saint John River, Canada, Using a Weight of Evidence Approach

Science.gov (United States)

Culp, J. M.; Luiker, E. A.; Noel, L.; Curry, A. R.; Hryn, D.; Heard, K.

2005-05-01

The Saint John River is the largest in Maine/New Brunswick (673 km in length, draining 55,000 km2) with a history of natural resource use and nutrient effluent release to the watershed since the late 17th century. Our objective was to obtain a basic understanding of the contemporary nutrient conditions of the non-tidal portion of the river in relation to historical conditions, and to consider how the contemporary river is affected by point and non-point source nutrient loadings. The study included review of historical provincial and federal water quality databases dating back to the 1960s. Current water quality monitoring programs have focused on nitrogen (nitrite, nitrate, ammonia, TKN), phosphorus (total, dissolved, and soluble reactive phosphorus), DIC/DOC, and biomass of periphyton and phytoplankton. To determine nutrient limitation, nutrient diffusing substrate studies were conducted in river reaches of known nutrient enrichment. Oxygen stable isotopes were also used to provide information on the photosynthesis to respiration ratio. A weight of evidence approach combining the results of these studies was used to determine trophic status of river reaches and to highlight areas of eutrophication. From this information nutrient criteria for the Saint John River will be proposed.

3rd International School and Conference “Saint Petersburg OPEN 2016” on Optoelectronics, Photonics, Engineering and Nanostructures

International Nuclear Information System (INIS)

2016-01-01

Dear Colleagues, 3rd International School and Conference “Saint Petersburg OPEN 2016” on Optoelectronics, Photonics, Engineering and Nanostructures was held on March 28 - 30, 2016 at St. Petersburg Academic University of the Russian Academy of Sciences. The School and Conference included a series of invited talks given by leading professors with the aim of introducing young scientists to the actual problems and major advances in modern physics and technology. The keynote speakers were Mircea Guina (Tampere University of Technology, Finland) Evgeny I. Terukov (Ioffe Institute RAS, Russia) Victor M. Ustinov (Ioffe Institute RAS, Russia) Peter G. Kazansky (University of Southampton, UK) Alexander O. Golubok (ITMO University, Russia) Georgy E. Cirlin (St Petersburg Academic University RAS, Russia) Levon V. Asryan (Virginia Polytechnic Institute and State University, USA) Andrey A. Lipovskii (Peter the Great St.Petersburg Polytechnic University, Russia) During the poster session all undergraduate and graduate students attending the conference presented their works. A large number of participants with more than 280 student attendees from all over the world allowed the Conference to provide a fertile ground for the fruitful discussions between the young scientists as well as to become a perfect platform for the valuable discussions between student authors and highly experienced scientists. The best student papers, which were selected by the Program Committee and by the invited speakers based on the theses and their poster presentation, were awarded with diplomas of the conference - see the photos. This year “Saint Petersburg OPEN 2016” is organized by St. Petersburg Academic University in cooperation with Peter the Great St. Petersburg Polytechnic University. The School and Conference is supported by the Russian Foundation for Basic Research (Project N 16-32-10060) , Russian Science Foundation, SPIE (The International Society for Optics and Photonics) and OSA (The

The Cerrado of Saint-Hilaire: naturalists representations of a 19th century French traveler

Directory of Open Access Journals (Sweden)

Lorena Borges Silva

2016-12-01

Full Text Available This work aims to investigate the different motivations and goals behind the traveler Saint-Hilarie intentions to invest in a project to enter the Cerrado, and from his narratives and perceptions, we intend to understand how the nature of the Cerrado was interpreted during the nineteenth century. We seek to see why so many derogatory assertions were made by observing the natural surroundings of Goiás.

La vision de Saint Eustathe dans la peinture post-byzantine

Directory of Open Access Journals (Sweden)

Amprazogoula Katerina

2008-01-01

Full Text Available (francuski L'article étudie l'évolution de la Vision de saint Eustathe dans une série de peintures murales et d'icônes portatives - allant du XVIe au XVIIIe siècle - les formules iconographiques adoptées et leurs particularités ainsi que la place et la fonction de cette image dans la peinture murale. Le matériel étudié a montré une diversité de formules iconographiques qui exploitent pour l'essentiel la tradition byzantine et orientale du sujet, en manifestant en même temps ses propres traits ainsi que l'influence des images occidentales. .

Inventory and action plan for greenhouse gas emissions and capture in the Lower Saint Lawrence

International Nuclear Information System (INIS)

Granger, F.; Avoine, G.; Michon, P.-Y.; Drainville, L.

2003-01-01

The authors reported on a project designed to provide farmers with concrete information based on data from their enterprise to develop an action plan for the reduction of greenhouse gas emissions. This project involved completing an inventory of greenhouse gas emissions and capture for seven farms located in the Lower Saint Lawrence region of Quebec. The authors presented a balance sheet and action plan for the region under study. A total of six priorities were identified. They encompassed measures such as the optimization of nitrogen management in agricultural soils, to increasing the capture rate of carbon dioxide, and reducing the use of fossil fuels. 6 refs., 6 figs

Les carbonates néogènes de Sainte Croix (Iles Vierges). Etude stratigraphique et pétrophysique Neogene Carbonates At Saint Croix, Virgin Islands. Stratigraphic and Petrophysical Study

OpenAIRE

Andreieff P.; Mascle A.; Mathieu Y.; Muller C.

2006-01-01

Un échantillonnage systématique des principaux affleurements des séries carbonatées néogènes de Sainte Croix (Iles Vierges) a permis de préciser leur extension stratigraphique. C'est ainsi que la section-type de la formation Kingshill, qui avait été récemment attribuée au Miocène supérieur, est désormais datée du Miocène moyen d'après son riche contenu faunistique en foraminifères planctoniques et nannofossiles calcaires. Les diverses mesures pétrophysiques effectuées dans des niveaux d'envir...

Une étude de cas. Saint Sébastien dans “Je suis sang” de Jan Fabre

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Lydie Toran

2017-06-01

Full Text Available Jan Fabre’s writing frequently displays a variety of quotations, especially visual ones. His 2001 Je suis sang (conte de fées médiéval is directly and indirectly inspired by Saint Sebastian’s iconography. This study examines the modalities and functions of this re-use in detail.

Digital dewaxing of Raman signals: discrimination between nevi and melanoma spectra obtained from paraffin-embedded skin biopsies.

Science.gov (United States)

Tfayli, Ali; Gobinet, Cyril; Vrabie, Valeriu; Huez, Regis; Manfait, Michel; Piot, Olivier

2009-05-01

Malignant melanoma (MM) is the most severe tumor affecting the skin and accounts for three quarters of all skin cancer deaths. Raman spectroscopy is a promising nondestructive tool that has been increasingly used for characterization of the molecular features of cancerous tissues. Different multivariate statistical analysis techniques are used in order to extract relevant information that can be considered as functional spectroscopic descriptors of a particular pathology. Paraffin embedding (waxing) is a highly efficient process used to conserve biopsies in tumor banks for several years. However, the use of non-dewaxed formalin-fixed paraffin-embedded tissues for Raman spectroscopic investigations remains very restricted, limiting the development of the technique as a routine analytical tool for biomedical purposes. This is due to the highly intense signal of paraffin, which masks important vibrations of the biological tissues. In addition to being time consuming and chemical intensive, chemical dewaxing methods are not efficient and they leave traces of the paraffin in tissues, which affects the Raman signal. In the present study, we use independent component analysis (ICA) on Raman spectral images collected on melanoma and nevus samples. The sources obtained from these images are then used to eliminate, using non-negativity constrained least squares (NCLS), the paraffin contribution from each individual spectrum of the spectral images of nevi and melanomas. Corrected spectra of both types of lesion are then compared and classified into dendrograms using hierarchical cluster analysis (HCA).

On elevated fluoride and boron concentrations in groundwaters associated with the Lake Saint-Martin impact structure, Manitoba

International Nuclear Information System (INIS)

Desbarats, Alexandre J.

2009-01-01

Hydrogeological investigations conducted by the Geological Survey of Canada in the Lake Saint-Martin region of Manitoba have confirmed earlier reports of naturally elevated F - and B concentrations in local groundwaters. Fluoride and B concentrations are highly correlated (r 2 = 0.905) and reach 15.1 mg/L and 8.5 mg/L, respectively. Virtually all groundwaters with F - concentrations greater than the drinking water limit of 1.5 mg/L are from wells within the Lake Saint-Martin impact structure, a 208 Ma complex crater 23 km in diameter underlying a large part of the study area. The high-F - groundwaters can be classified into two groups according to their anionic and isotopic compositions. Group I samples consist of Na-mixed anion groundwaters, with Cl greater than 100 mg/L and highly depleted 18 O compositions indicative of recharge under much cooler climatic conditions than at present. Samples belonging to this group exhibit a striking relationship to crater morphology, and are found in an arcuate belt within the southern rim of the impact structure. Group II high-F - samples consist of Na-HCO 3 -SO 4 groundwaters, with little Cl, and less depleted 18 O compositions. Samples belonging to this group are associated with groundwaters recharged locally, on a low ridge within the impact structure. This paper traces the probable source of high-F - groundwaters to phosphatic pellets in shales of the Winnipeg Formation, a regional basal clastic unit which sub-crops at shallow depth beneath the crater rim as a result of more than 200 m of structural uplift associated with the impact event. This extensive aquifer is known elsewhere in southern Manitoba for its naturally-softened groundwaters and locally elevated F - concentrations. Group I groundwaters are interpreted as discharge from the Winnipeg Formation where it abuts against crater-fill deposits. Group II high-F - groundwaters are interpreted as modern recharge from within the impact structure, displacing Group I

Santa Rosa de Lima: uma santa anoréxica na América Latina? Santa Rosa de Lima: ¿una santa anoréxica en Latinoamérica? Saint Rose of Lima: an anorexic saint in Latin America?

Directory of Open Access Journals (Sweden)

Cybelle Weinberg

2005-04-01

Full Text Available A literatura especializada tem nos mostrado que é grande a semelhança entre o comportamento alimentar das santas jejuadoras medievais e o das anoréxicas atuais. No entanto, há poucas referências sobre a existência de santas jejuadoras na América Latina. No presente trabalho, os autores salientam aspectos da vida de Santa Rosa de Lima, Patrona da América e Filipinas, que poderiam ser descritos como comportamentos anoréxicos. Comparando os aspectos psicopatológicos da vida de Santa Rosa com o comportamento das anoréxicas atuais, pareceu confirmar-se um padrão uniforme de comportamento, especialmente quanto ao aspecto imitativo, fator que poderia levar as jovens da atualidade a desenvolverem um transtorno alimentar após terem algum tipo de informação sobre o transtorno.La literatura especializada nos muestra gran similitud entre el comportamiento alimentar de las santas de la edad media que ayunaban y el de las anoréxicas de la actualidad. Hay pocas informaciones sobre santas que practicaban ayuno en Latinoamérica. En este artículo, los autores resaltan aspectos de la vida de santa Rosa de Lima, Patrona de América y Filipinas, que pueden ser considerados como comportamientos anoréxicos. Al comparar aspectos psicopatológicos de la vida de santa Rosa con el comportamiento de anoréxicas de la actualidad, parece que se confirma un modelo uniforme de comportamiento, especialmente respecto al aspecto de imitación, hecho que podría llevar a las jóvenes de hoy a desarrollar un trastorno de la alimentación luego de recibir informaciones sobre el tema.The specialized literature has shown us the great similarity between the eating habits of medieval fasting women saints and today's anorexic women. Nonetheless, there are few references to the existence of such fasting women saints in Latin America. The authors of this paper present some aspects of the life of Saint Rose of Lima, the patroness of the Americas and the Philippines, that

The Use of Dual Forms in the “Collection of Lives of Greek Saints” by Saint Nilus of Sora

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Polina Yuryevna Karavaeva

2015-09-01

Full Text Available In this article we reveal the key principles of dual contexts in Hagiography 'Life of Saint Simeon Stylites of the Admirable Mountain' and 'Life of Saint Onoufrios of the Desert', which are included into the "Collection of Lives of Greek Saints". We proceed from the discrepancy between the history of dual number in colloquial language and book-Slavic language. And we consider the form of dual number as a sign of book-Slavic grammatical norm in the period of the end of 15th - beginning of the 16th centuries. St. Nilus of Sora uses dual number not only with certain stylistic purposes, but also as a clear indication that a text is a monument, that implements strict grammatical norms of Church Slavonic Russian. We provide the most detailed description of the features of the use of free dual forms and also the description of the features of the use of associated dual number. According to the classification, which was proposed by A. Belich, free dual number refers to symmetrical objects, usually of the free dual number are the most stable and consistent in its use. So, one of the features of the representations of St. Nilus of Sora and his disciples about the grammatical norm of using dual number forms is used as a grammatical synonymic forms of the plural and dual number of verb forms in the combination of a noun with a numeral "two".

SAINT APOLLONIA: BETWEEN PAGANISM AND CHRISTIANITY IN MEDICINE

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Gheorghe Gh. BĂLAN

2015-03-01

Full Text Available The history of medicine and dentistry shows that dental medicine is entitled to take upon itself, as representative elements of the field, symbols or spiritual protectors, religious (either Christian or pagan archetypes from different historical periods. These paved the way for the elaboration of a long-lasting set of professional and ethical criteria that ennoble today the dental profession. The present study analyzes some of the symbols of historical-religious nature, stressing their cultural impact and the manner in which such symbols are interpreted in various scientific, medical, theological, artistic contexts and, last but not least, in the general social perception. The professional ethical domain of dentistry makes use of numerous symbols with religious connotation, the more so that this branch of medicine and the various religions have numerous elements in common. Either stylistically, or appearing as products of folk culture, the main symbolistic or legendary references specific to dental culture are the legend of Cadmus and the canonization of Saint Apollonia, the champion of dentists and of those suffering from toothache. Such symbols give to the representatives of this profession a feeling of belonging to a noble medical domain; they also decode and facilitate communication with patients, therefore being outflanked by the idea that awareness on the existence of such religious symbols and on their practical cohesion is especially helpful.

How did Death become a Saint in Mexico?

DEFF Research Database (Denmark)

Kristensen, Regnar Albæk

2014-01-01

Over the last decade, the cult of La Santa Muerte (St Death) has attracted a remarkable number of followers in Mexico and the USA. Whereas the social context of her devotees, who tend to live on the fringes of society, has attracted ample attention from scholars and journalists, one of the princi......Over the last decade, the cult of La Santa Muerte (St Death) has attracted a remarkable number of followers in Mexico and the USA. Whereas the social context of her devotees, who tend to live on the fringes of society, has attracted ample attention from scholars and journalists, one...... of the principal puzzles is still how a skeleton image of death has come to be seen as a saint by large numbers of Catholics. How is it possible for this figure to embrace such antagonistic qualities as death and sainthood in a Christian context? In this semiotic-material exploration of the image’s genealogy, I...

Saint-Laurent-des-Eaux nuclear facilities. 2009 annual report

International Nuclear Information System (INIS)

2010-01-01

This annual report is established on account of article 21 of the 2006-686 French law from June 13, 2006, relative to the transparency and safety in the nuclear domain. It describes, first, the nuclear facilities of Saint-Laurent-des-Eaux, and then the measures taken to ensure their safety (personnel radioprotection, actions implemented for nuclear safety improvement, organisation in crisis situation, external and internal controls, technical assessment of the facilities, administrative procedures carried out in 2009), incidents and accidents registered in 2009, radioactive and chemical effluents released by the facilities in the environment, other pollutions, management of radioactive wastes, and, finally, the actions carried out in the domain of transparency and public information. A glossary and the viewpoint of the Committee of Hygiene, safety and working conditions about the content of the document conclude the report. (J.S.)

Segmented Aperture Interferometric Nulling Testbed (SAINT) II: component systems update

Science.gov (United States)

Hicks, Brian A.; Bolcar, Matthew R.; Helmbrecht, Michael A.; Petrone, Peter; Burke, Elliot; Corsetti, James; Dillon, Thomas; Lea, Andrew; Pellicori, Samuel; Sheets, Teresa; Shiri, Ron; Agolli, Jack; DeVries, John; Eberhardt, Andrew; McCabe, Tyler

2017-09-01

This work presents updates to the coronagraph and telescope components of the Segmented Aperture Interferometric Nulling Testbed (SAINT). The project pairs an actively-controlled macro-scale segmented mirror with the Visible Nulling Coronagraph (VNC) towards demonstrating capabilities for the future space observatories needed to directly detect and characterize a significant sample of Earth-sized worlds around nearby stars in the quest for identifying those which may be habitable and possibly harbor life. Efforts to improve the VNC wavefront control optics and mechanisms towards repeating narrowband results are described. A narrative is provided for the design of new optical components aimed at enabling broadband performance. Initial work with the hardware and software interface for controlling the segmented telescope mirror is also presented.

Farewell to Fiestas and Saints? Changing Catholic Practices in Contemporary Rural Oaxaca

Directory of Open Access Journals (Sweden)

Toomas Gross

2011-03-01

Full Text Available This article discusses recent changes in Catholic festivities, especially the system of fiestas in rural Mexico. The ethnographic focus of the discussion is on indigenous Zapotec communities of the State of Oaxaca. Collective religious practices in Mexican villages contribute to social cohesion. Fiestas commemorating patron saints of the villages play a particularly important role in (reconstructing communal identity and the feeling of collective belongingness. Various global processes like secularisation, integration of local economies into the capitalist market system, increasing out-migration from villages, and the rise of Protestantism have undermined the position of the Catholic Church in the region. The article scrutinises the changing organisation and role of fiestas in the communities, concluding that the impact of secularisation, migration and Protestantism in particular is not simple and always negative – these changes can actually invigorate certain dimensions of the fiestas.

The Performance of the Robo-AO Laser Guide Star Adaptive Optics System at the Kitt Peak 2.1 m Telescope

Science.gov (United States)

Jensen-Clem, Rebecca; Duev, Dmitry A.; Riddle, Reed; Salama, Maïssa; Baranec, Christoph; Law, Nicholas M.; Kulkarni, S. R.; Ramprakash, A. N.

2018-01-01

Robo-AO is an autonomous laser guide star adaptive optics (AO) system recently commissioned at the Kitt Peak 2.1 m telescope. With the ability to observe every clear night, Robo-AO at the 2.1 m telescope is the first dedicated AO observatory. This paper presents the imaging performance of the AO system in its first 18 months of operations. For a median seeing value of 1.″44, the average Strehl ratio is 4% in the i\\prime band. After post processing, the contrast ratio under sub-arcsecond seeing for a 2≤slant i\\prime ≤slant 16 primary star is five and seven magnitudes at radial offsets of 0.″5 and 1.″0, respectively. The data processing and archiving pipelines run automatically at the end of each night. The first stage of the processing pipeline shifts and adds the rapid frame rate data using techniques optimized for different signal-to-noise ratios. The second “high-contrast” stage of the pipeline is eponymously well suited to finding faint stellar companions. Currently, a range of scientific programs, including the synthetic tracking of near-Earth asteroids, the binarity of stars in young clusters, and weather on solar system planets are being undertaken with Robo-AO.

Scyllarides obtusus spec. nov., the scyllarid lobster of Saint Helena, Central South Atlantic (Crustacea: Decapoda Reptantia: Scyllaridae)

NARCIS (Netherlands)

Holthuis, L.B.

1993-01-01

A new species of slipper lobster is described from Saint Helena, where the species seems to be endemic. Known under the vernacular name Stump, the species forms the subject of a local fishery, carried out since early times. Previously the species has been identified with various Scyllarides species

Religious [Out]Laws: An Analysis of the 2008 Fundamentalist Latter-day Saints Raid

OpenAIRE

Ambutter, Cassie Nicole

2014-01-01

In early April 2008, based on a single allegation of child abuse, the state of Texas and Child Protective Services (CPS) executed a raid on the Fundamentalist Latter-day Saints, a polygamous Mormon group living on the "Yearning for Zion" ranch in Eldorado, Texas. The raid involved the immediate removal of over 400 children who were then placed in protective custody in nearby San Angelo. Despite the fact that the initial abuse allegation was determined to be a hoax, the raid was the catalyst f...

Educação integral: notas sobre Charles Fourier, Saint Simon e Pierre-Joseph Proudhon

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José Damiro Moraes

2015-11-01

Full Text Available Este artigo procura contribuir para as discussões em torno do conceito histórico de educação integral, tendo em vista que existem algumas lacunas em torno desse tema. Aqui iremos abordar os conceitos de educação integral no pensamento dos intelectuais: Claude-Henri de Rouvroy ou Conde de Saint-Simon (1760-1825, François Marie Charles Fourier (1772-1837 e Pierre-Joseph Proudhon (1809-1865. A pesquisa utiliza as obras dos autores escritas/publicadas no século XIX. A metodologia procura entender a produção intelectual de maneira dialética e dentro do contexto histórico em que foi produzida. Indicamos como conclusões que Proudhon, Saint-Simon e Charles Fourier, consideravam no processo educacional que a parte literária estaria diretamente vinculada com a científica, unindo teoria e prática. Podemos aventar que as contribuições desses pensadores foram importante nas reflexões educacionais e na defesa de uma educação comprometida com a transformação social presente no pensamento socialista e no movimento operário do século XIX e XX.

Integrating Volcanic Hazard Data in a Systematic Approach to Develop Volcanic Hazard Maps in the Lesser Antilles

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Jan M. Lindsay

2018-04-01

Full Text Available We report on the process of generating the first suite of integrated volcanic hazard zonation maps for the islands of Dominica, Grenada (including Kick ‘em Jenny and Ronde/Caille, Nevis, Saba, St. Eustatius, St. Kitts, Saint Lucia, and St Vincent in the Lesser Antilles. We developed a systematic approach that accommodated the range in prior knowledge of the volcanoes in the region. A first-order hazard assessment for each island was used to develop one or more scenario(s of likely future activity, for which scenario-based hazard maps were generated. For the most-likely scenario on each island we also produced a poster-sized integrated volcanic hazard zonation map, which combined the individual hazardous phenomena depicted in the scenario-based hazard maps into integrated hazard zones. We document the philosophy behind the generation of this suite of maps, and the method by which hazard information was combined to create integrated hazard zonation maps, and illustrate our approach through a case study of St. Vincent. We also outline some of the challenges we faced using this approach, and the lessons we have learned by observing how stakeholders have interacted with the maps over the past ~10 years. Based on our experience, we recommend that future map makers involve stakeholders in the entire map generation process, especially when making design choices such as type of base map, use of colour and gradational boundaries, and indeed what to depict on the map. We also recommend careful consideration of how to evaluate and depict offshore hazard of island volcanoes, and recommend computer-assisted modelling of all phenomena to generate more realistic hazard footprints. Finally, although our systematic approach to integrating individual hazard data into zones generally worked well, we suggest that a better approach might be to treat the integration of hazards on a case-by-case basis to ensure the final product meets map users' needs. We hope that

Sedimentary Records of Hyperpycnal Flows and the Influence of River Damming on Sediment Dynamics of Estuaries: Examples from the Nelson, Churchill, Moisie and Sainte-Marguerite Rivers (Canada)

Science.gov (United States)

St-Onge, G.; Duboc, Q.; Boyer-Villemaire, U.; Lajeunesse, P.; Bernatchez, P.

2015-12-01

Sediment cores were sampled in the estuary of the Nelson and Churchill Rivers in western Hudson Bay, as well as in the estuary of the Moisie and Sainte-Marguerite Rivers in Gulf of St. Lawrence in order to evaluate the impact of hydroelectric dams on the sedimentary regime of these estuaries. The gravity cores at the mouth of the Nelson River recorded several cm-thick rapidly deposited layers with a reverse to normal grading sequence, indicating the occurrence of hyperpycnal flows generated by major floods during the last few centuries. These hyperpycnal flows were probably caused by ice-jam formation, which can increase both the flow and the sediment concentration following the breaching of such natural dams. Following the construction of hydroelectric dams since the 1960s, the regulation of river discharge prevented the formation of hyperpycnal flows, and hence the deposition of hyperpycnites in the upper part of the cores. In the core sampled in the estuary of the Churchill River, only one hyperpycnite was recorded. This lower frequency may be due to the enclosed estuary of the Churchill River, its weaker discharge and the more distal location of the coring site.In the Gulf of St. Lawrence, grain size measurements allowed the identification of a major flood around AD 1844±4 years in box cores from both the Sainte-Marguerite and Moisie Rivers, whereas a drastic decrease in variations in the median grain size occurred around AD ~1900 in the estuary of the Sainte-Marguerite River, highlighting the offshore impact of the SM1 dam construction in the early 1900s. Furthermore, sedimentological variations in the box cores from both estuaries have been investigated by wavelet analysis and the sharp disappearance of high frequencies around AD 1900 in the estuary of the dammed river (Sainte-Marguerite River), but not in the estuary of the natural river (Moisie River), also provides evidence of the influence of dams on the sedimentary regime of estuaries.

The circulation of Ghlin flint during the time of the Blicquy - Villeneuve-Saint-Germain culture (Early Neolithic

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Solène Denis

2014-03-01

Full Text Available In the North of France and Belgium, the Blicquy - Villeneuve-Saint-Germain culture marks the end of the Early Neolithic Period (beginning of the 5th millennium. The Blicquy group is constituted of eleven sites located in Belgium, with two main centers of occupation: one Western in Hainaut and one Eastern in Hesbaye, 100 km away from the first. As part of a PhD, the lithic industry of these sites is studied in order to reconstruct the circulation networks through a techno-economic analysis. It has been complex to identify the raw materials, given the lack of information about the siliceous outcrops in the Mons Basin. However, two main circulation networks have been highlighted: one of Ghlin flint and one of tertiary Bartonian flint. These two types of flint are indeed easily recognizable by their macroscopic characteristics. The outcrops of tertiary Bartonian flints originate from the Paris Basin, where systematic surveys have been conducted since the late 1980s. The circulation of tertiary Bartonian flint is now well-known and emblematic of the Blicquy - Villeneuve-Saint-Germain culture. Therefore, this paper will focus on the circulation of Ghlin flint in the Blicquy-Villeneuve-Saint-Germain culture. The Ghlin flint shows on the surface in the Mons Basin, about twenty kilometers away from the Hainaut sites. Heavily exploited in the latter, it was exported to the Hesbaye sites in a significant way, despite the availability of siliceous resources available in Hesbaye. Moreover, some artifacts circulated towards the Paris Basin. The study of the circulation of Ghlin flint can therefore help to determine the socio-economic organization of these populations by specifying the linkages between the population centers of Hainaut, Hesbaye and Paris Basin.

Antibiotic use practices of pharmacy staff: a cross-sectional study in Saint Petersburg, the Russian Federation.

Science.gov (United States)

Belkina, Tatiana; Duvanova, Natalia; Karbovskaja, Julia; Tebbens, Jurjen Duintjer; Vlcek, Jiri

2017-02-14

Non-prescription access to antimicrobials is common, and self-prescribing is increasingly popular in Russian society. The aim of this study was to assess the attitudes of community pharmacists regarding antibiotic use and self-medication. We conducted a cross-sectional study from September-December 2015 of community pharmacists in the Saint-Petersburg and Leningrad region, Russia. A self-administered questionnaire was used to assess antibiotic use and self-medication practices. The data were analysed using logistic regression and Pearson chi-squared tests. Of the 316 pharmacists (77.07%) who completed the questionnaire, 230 (72.8%) self-medicated with antibiotics. Antibiotics were mostly used to self-treat upper (53.3%) and lower respiratory tract infections (19.3%), relying on their own knowledge (81.5%), previous treatment experience (49%) and patients' prescriptions (17%). The most commonly used antibiotics were macrolides (33.2%). Characteristics such as age, education and experience were related to antibiotic use and self-medication. The study confirmed that self-prescription of antibiotics is a common practice amongst pharmacists in Saint Petersburg and also identified personal and professional characteristics of pharmacists strongly associated with self-medication.

77 FR 15600 - Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL

Science.gov (United States)

2012-03-16

...-AA08 Special Local Regulation; Emerald Coast Super Boat Grand Prix; Saint Andrew Bay; Panama City, FL... navigable waters during the Emerald Coast Super Boat Grand Prix high speed boat races. Entry into... needed to safeguard persons and vessels from safety hazards associated with the Emerald Coast Super Boat...

Chemical and isotopic composition of high-temperature gases from the new Andesitic lava dome in the Soufriere of Saint-Vincent (Lesser Antilles)

International Nuclear Information System (INIS)

Allard, Patrick

1981-01-01

High-temperature gases emitted by the new lava dome built within the crater of the Soufriere of Saint-Vincent, in 1979, were collected. Their chemical composition and a possible deep-seated origin for carbon (mean delta 13 C=-5.5 0/00 vs PDB) are discussed here [fr

Chemical and isotopic composition of high-temperature gases from the new Andesitic lava dome in the Soufriere of Saint-Vincent (Lesser Antilles)

Energy Technology Data Exchange (ETDEWEB)

Allard, P. (Centre des Faibles radioactivites, Gif-sur-Yvette (France))

1981-11-09

High-temperature gases emitted by the new lava dome built within the crater of the Soufriere of Saint-Vincent, in 1979, were collected. Their chemical composition and a possible deep-seated origin for carbon (mean delta/sup 13/C=-5.5 0/00 vs PDB) are discussed here.

Study of production by cosmic radiation of krypton and xenon in the Saint-Severin meteorite

International Nuclear Information System (INIS)

Lavielle, B.

1987-01-01

The concentrations of Kr and Xe isotropes have been measured by a high sensitivity mass spectrometry technique in 11 samples from a core of the Saint-Severin meteorite. On the basis of our results, we were able to show the role of the shielding depth on the production of Kr and Xe by cosmic ray bombardment. More-over, the experimental results for krypton were compared with calculated values obtained by the Reedy and Arnold model (1972) adapted to cosmic ray irradiation of small spherical objects. Our elaboration of a new systematics of nuclear reactions has lead to a good agreement between experiments and calculations within this model [fr

Los juegos antropologicos de Saint-Louis

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Fabrice Delsahut

2011-12-01

Full Text Available En 1904, en medio de la feria de la exposición universal de Saint-Louis, los Juegos olimpicos no pudieron escapar a la ascención de ideologías racistas del principios del siglo XX y contibuyeron a la discusión del mérito atlético de diferentes razas. Los organisadores prepararon competiciones especiales que llamaron en esta ocasión «Jornadas antropológicas» reservadas a los que la América segregacionista del momento consideraba como primitivos. El impacto de los estudios sobre las razas, sobre la manera de pensar en el deporte no fue, al contrario de lo que se esforzaron hacer creer los diferentes presidentes del C.O.I en el curso de las siguientes decadas, un simple avatar del movimiento olimpico. Veremos la influencía de este espectáculo atletico interracial en los Estados Unidos pero tambien en el mundo, particularmente a través del papel de la prensa. Las jornadas antropológicas permitieron indudablemente elaborar una cierta percepción de la otricidad y limitaran la integración de los pueblos autóctonas en la maquina deportiva mundial.

Architecture, religion, and tuberculosis in Sainte-Agathe-des-Monts, Quebec.

Science.gov (United States)

Adams, Annmarie; Poutanen, Mary Anne

2009-01-01

This paper explores the architecture of the Mount Sinai Sanatorium in Sainte-Agathe-des-Monts (Qc) to disentangle the role of religion in the treatment of tuberculosis. In particular, we analyze the design of Mount Sinai, the jewel in the crown of Jewish philanthropy in Montreal, in relation to that of the nearby Laurentian Sanatorium. While Mount Sinai offered free treatment to the poor in a stunning, Art Deco building of 1930, the Protestant hospital had by then served paying patients for more than two decades in a purposefully home-like, Tudor-revival setting. Using architectural historian Bernard Herman's concept of embedded landscapes, we show how the two hospitals differed in terms of their relationship to site, access, and, most importantly, to city, knowledge, and community. Architects Scopes & Feustmann, who designed the Laurentian hospital, operated an office at Saranac Lake, New York, America's premier destination for consumptives. The qualifications of Mount Sinai architects Spence & Goodman, however, derived from their experience with Jewish institutions in Montreal. Following Herman's approach to architecture through movement and context, how did notions of medical therapy and Judaism intersect in the plans of Mount Sinai?

The diluvial rains of Saguenay-Lac-Saint-Jean : status one year after

International Nuclear Information System (INIS)

Henri, N.; Beauchemin, G.; Alonso, M.; Gelinas, M.

1997-01-01

The status of damages and reconstruction in the Saguenay-Lac-Saint-Jean region, one year after the catastrophic torrential rain storm of July 1996 was presented. Numerous detailed maps and photographs of the principal washed-out, destroyed and damaged regions were presented, along with maps and photographs of the same areas after reconstruction, repair and landscaping. The maps show the different river beds, urban, and rural districts that were subjected to the catastrophic washouts, landslides and soil collapses. The report also includes a summary of the repair costs by municipal regions and the financial aid received by the region to help in the reconstruction effort. tabs., figs

Families in terms of the Saint Pius X Brotherhood in the journal “Always Faithful” [Rodzina na łamach czasopisma „Zawsze Wierni” Bractwa Świętego Piusa X

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Dominik FIGIEL

2017-11-01

Full Text Available Issues of the roles, functions, and responsibilities of families are repeatedly discussed by the Church. Marriage, family and fatherhood are the main values which the Church defends. But there is a context of divergent views: post-council (Second Vatican Council Church versus the Saint Pius X Brotherhood which has been established by Marcel Lefebrve. Issues of Integrism have been still raised by the contemporary Church, which does not agree with the views of the Saint Pius X Brotherhood. This division came after the Second Vatican Council. This is particularly important because in a social context the integrists views are extremely radical. The fulfilling of the religious function which is based on the Saint Pius X Brotherhood thoughts can cause difficulties in accommodating oneself within a multicultural, multireligious social reality. From this point of view, family and its image presented in the Brotherhood journal “Always Faithful” are important. The radical views of integrists on ecumenism, religious freedom, liberalism and modernism displaythe attitude toward other religions. All views, attitudes and actions directed towards the objections to modernist changes are called integrism, and its representatives are integrists. Analysis of magazines, encyclicals and speeches propagated by members of the Saint Pius X Brotherhood allowsa view of the family from the Catholic tradition. The modernistic approach of the contemporary Church and presenting family in that context is at variance with views which have been propagated by Integrists. In turn the Saint Pius X Brotherhood and the propagated traditional views do not respond to the needs of the contemporary reality – not only in religious terms but also social ones.

Dos lienzos firmados por Alonso del Arco en la parisina iglesia Saint-François de Sales

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Delenda, Odile

2004-09-01

Full Text Available El inventario detallado realizado en las iglesias de París por los conservadores des Oeuvres d'Art Religieuses et Civiles del ayuntamiento de la capital francesa, puede reservar gratas sorpresas. Muy recientemente Guénola Groud, conservateur du Patrimoine y su equipo, pudieron localizar en la «Salle des mariages» de la nueva iglesia de Saint-François-de-Sales (Paris, XVIIème dos importantes lienzos de medio punto, la Adoración de los Pastores (Fig. 2 y la Adoración de los Magos (Fig. 1 firmados por el pintor Alonso del Arco (1635-1704 colaborador y discípulo de Antonio Pereda. Existen en efecto dos iglesias Saint-François-de-Sales. La más antigua, de 1873, está situada en la calle Brémontier mientras que la más reciente, construida entre 1911 y 1913, tiene su entrada principal en la calle Ampère…

Supercar Experience | 6 September | Saint-Julien-en-Genevois

CERN Multimedia

2015-01-01

On Sunday, 6 September, don’t miss the fourth Supercars Experience day (see here) organised by members of CERN and the Les Amis Porschistes du Léman association.   Supercars at the 2014 experience day. Photo: Kevin Mazzilli. From 9.30 a.m. to 6 p.m., in the Vitam leisure centre car park (Saint-Julien-en-Genevois), the owners of around 50 supercars (Porsche, Ferrari, Lamborghini, Lotus, Venturi, and more) will be offering passengers rides lasting 10 to 15 minutes. For 10 euros, you can go for a spin in a sports car; for 50 euros, you can choose one of the most prestigious models. All of the money collected will go to the Kumansansa association, which helps disadvantaged children in Zambia. “Since the first edition in 2012, the event has been a real success with the public, and the money collected each year allows us to put into action our initiatives with children in Zambia,” says François Butin, co-organiser with ...

Attitudes and practices of pesticide users in Saint Lucia, West Indies.

Science.gov (United States)

McDougall, L; Magloire, L; Hospedales, C J; Tollefson, J E; Ooms, M; Singh, N C; White, F M

1993-01-01

This article reports the results of a Saint Lucia survey, part of a larger program, that was the first to document the prevalence of suboptimal safety practices among vector control and farm workers using pesticides in the English-speaking Caribbean. Among other things, the survey found that many of 130 pesticide users surveyed were unaware that the skin and eyes were important potential routes of absorption. Over a quarter said they had felt ill at some point as a result of pesticide use. About half the respondents said they had received more than "introductory" training in safe pesticide use, and most said they always found labels or directions affixed to pesticide containers. However, about half said they never or only sometimes understood the labels, and many of those who said they understood did not always follow the instructions. About a quarter of the smokers said they smoked while using pesticides; about a sixth of the survey subjects said they ate food while using pesticides; and over 60% said they never wore protective clothing.

Targeting Rapamycin to Podocytes Using a Vascular Cell Adhesion Molecule-1 (VCAM-1-Harnessed SAINT-Based Lipid Carrier System.

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Ganesh Ram R Visweswaran

Full Text Available Together with mesangial cells, glomerular endothelial cells and the basement membrane, podocytes constitute the glomerular filtration barrier (GFB of the kidney. Podocytes play a pivotal role in the progression of various kidney-related diseases such as glomerular sclerosis and glomerulonephritis that finally lead to chronic end-stage renal disease. During podocytopathies, the slit-diaphragm connecting the adjacent podocytes are detached leading to severe loss of proteins in the urine. The pathophysiology of podocytopathies makes podocytes a potential and challenging target for nanomedicine development, though there is a lack of known molecular targets for cell selective drug delivery. To identify VCAM-1 as a cell-surface receptor that is suitable for binding and internalization of nanomedicine carrier systems by podocytes, we investigated its expression in the immortalized podocyte cell lines AB8/13 and MPC-5, and in primary podocytes. Gene and protein expression analyses revealed that VCAM-1 expression is increased by podocytes upon TNFα-activation for up to 24 h. This was paralleled by anti-VCAM-1 antibody binding to the TNFα-activated cells, which can be employed as a ligand to facilitate the uptake of nanocarriers under inflammatory conditions. Hence, we next explored the possibilities of using VCAM-1 as a cell-surface receptor to deliver the potent immunosuppressant rapamycin to TNFα-activated podocytes using the lipid-based nanocarrier system Saint-O-Somes. Anti-VCAM-1-rapamycin-SAINT-O-Somes more effectively inhibited the cell migration of AB8/13 cells than free rapamycin and non-targeted rapamycin-SAINT-O-Somes indicating the potential of VCAM-1 targeted drug delivery to podocytes.

From Hillforts to Saints: Sun Tropoi and Patterns of Christianization in NW Spain

Science.gov (United States)

Quintela, Marco V. García; García, A. César González; Veiga, Yolanda Seoane

2015-05-01

We present three Iron Age landscapes in the province of Ourense (northwest Spain), consisting of a hill fort with an acropolis used for religious purposes, and an "extra-urban" location used for ritual functions. Both locations are associated with the solstices, corroborating the validity of considering them jointly in each case, and the three cases jointly as a model. In the three locations, the oldest Christian saints and festivals we are able to identify re-use the dates of the solstices, and others, marked by Iron Age monuments. These observations open the way for research in several directions: the definition of religious landscapes from the Iron Age; the reason why there is not a 'Roman landscape'; the relationship between the Indo-European legacy and the introduction of Christianity; and the relationship between local calendars and the Celtic, Julian and Gregorian 'cultural' calendars.

L’enclos Saint-Césaire à Arles, un chantier controversé

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Marc Heijmans

2010-03-01

Full Text Available Contrairement à la plupart des sites présentés lors de ces journées à Luxeuil, le cas de la fouille de l’enclos Saint-Césaire d’Arles n’en est qu’à ses débuts, et rien ne garantit actuellement que le site sera un jour présenté, pour tout ou partie, au public. Sans vouloir dire que c’est un exemple à ne pas suivre, il montre la lente évolution d’un projet de rénovation où l’importance du patrimoine antique et médiéval n’a été que progressivement prise en compte. Cette contribution présente don...

Translation to Spanish and Validation of the Specific Saint George's Questionnaire for Idiopathic Pulmonary Fibrosis.

Science.gov (United States)

Capparelli, Ignacio; Fernandez, Martín; Saadia Otero, Marcela; Steimberg, Jimena; Brassesco, María; Campobasso, Ana; Palacios, Sandra; Caro, Fabian; Alberti, María Laura; Rabinovich, Roberto A; Paulin, Francisco

2018-02-01

Interstitial lung disease (ILD) is associated with low exercise tolerance, dyspnea, and decreased health-related quality of life (HRQL). Idiopathic pulmonary fibrosis (IPF) is one of the most prevalent in the group. A specific version of the Saint George's questionnaire (SGRQ-I) has been developed to quantify the HRQL of IPF patients. However, this tool is not currently validated in the Spanish language. The objective was to translate into Spanish and validate the specific Saint George's Respiratory Questionnaire for idiopathic pulmonary fibrosis (SGRQ-I). The repeatability, internal consistency and construct validity of the SGRQ-I in Spanish were analyzed after a backtranslation process. In total, 23 outpatients with IPF completed the translated SGRQ-I twice, 7 days apart. Repeatability was studied, revealing good concordance in test-retest with an ICC (interclass correlation coefficient) of 0.96 (P<.001). Internal consistency was good for different questionnaire items (Cronbach's alpha of 0.9 including and 0.81 excluding the total value) (P<.001). The total score of the questionnaire showed good correlation with forced vital capacity FVC% (r=-0.44; P=.033), diffusing capacity of the lungs for carbon monoxide (DL CO %) (r=-0.55; P=.011), partial pressure of oxygen in arterial blood PaO 2 (r=-0.44; P=.036), Medical Research Council Dyspnea scale (r=-0.65; P<.001), and number of steps taken in 24hours (r=-0.47; P=.024). The Spanish version of SGRQ-Ideveloped by our group shows good internal consistency, reproducibility and validity, so it can be used for the evaluation of quality of life (QOL) in IPF patients. Copyright © 2017 SEPAR. Publicado por Elsevier España, S.L.U. All rights reserved.

A Proposed Community Network For Monitoring Volcanic Emissions In Saint Lucia, Lesser Antilles

Science.gov (United States)

Joseph, E. P.; Beckles, D. M.; Robertson, R. E.; Latchman, J. L.; Edwards, S.

2013-12-01

Systematic geochemical monitoring of volcanic systems in the English-speaking islands of the Lesser Antilles was initiated by the UWI Seismic Research Centre (SRC) in 2000, as part of its volcanic surveillance programme for the English-speaking islands of the Lesser Antilles. This programme provided the first time-series observations used for the purpose of volcano monitoring in Dominica and Saint Lucia, permitted the characterization of the geothermal fluids associated with them, and established baseline studies for understanding of the hydrothermal systems during periods of quiescence (Joseph et al., 2011; Joseph et al., 2013). As part of efforts to improve and expand the capacity of SRC to provide volcanic surveillance through its geothermal monitoring programme, it is necessary to develop economically sustainable options for the monitoring of volcanic emissions/pollutants. Towards this effort we intend to work in collaboration with local authorities in Saint Lucia, to develop a monitoring network for quantifying the background exposure levels of ambient concentrations of volcanic pollutants, SO2 in air and As in waters (as health significant marker elements in the geothermal emissions) that would serve as a model for the emissions monitoring network for other volcanic islands. This programme would facilitate the building of local capacity and training to monitor the hazardous exposure, through the application and transfer of a regionally available low-cost and low-technology SO2 measurement/detection system in Saint Lucia. Existing monitoring technologies to inform evidence based health practices are too costly for small island Caribbean states, and no government policies or health services measures currently exist to address/mitigate these influences. Gases, aerosols and toxic elements from eruptive and non-eruptive volcanic activity are known to adversely affect human health and the environment (Baxter, 2000; Zhang et al., 2008). Investigations into the

MIDSUMMER (SAINT JOHN’S FEAST IN IRELAND: THE OLD AND THE NEW

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TIZIANA SOVERINO

2016-04-01

Full Text Available “Bonfire Night”, or Oíche Fhéile Eóin (“Saint John’s Night”, has been observed in parts of Ireland for centuries. The earliest documentary evidence of the lighting of bonfires on the eve of the feast, 23 June, dates to the 17th century. The custom was so important that it gave rise to the appellation “Bonfire Night”. In the west of the country, and elsewhere, such as in Cork city, bonfire celebrations seem strong even recently. However, to survive, they must kaleidoscopically adapt to everchanging circumstances. Drawing on a range of sources – from the unpublished replies to National Folklore Collection (NFC questionnaires, to twenty-first century local newspapers, and to fieldwork undertaken in 2008 – three major changes in this custom have been identified: the material allowed in the fires, the commercialisation of bonfires, and the withdrawal of a certain part of the population from the festivities. The article will explore complementary reasons behind these trends

Picosecond 532-nm neodymium-doped yttrium aluminum garnet laser-a promising modality for the management of verrucous epidermal nevi.

Science.gov (United States)

Levi, Assi; Amitai, Dan Ben; Mimouni, Daniel; Leshem, Yael A; Arzi, Ofir; Lapidoth, Moshe

2018-04-01

The verrucous epidermal nevus (VEN) is the most common type of epidermal nevi. As lesions can be disfiguring, treatment is often sought. Many therapeutic approaches have been reported, with variable efficacy and safety. Picosecond (PS) lasers are novel laser devices designated to target small chromophores. A side effect of these lasers is blistering due to epidermal-dermal separation. We aimed to harness this side effect of the PS lasers to treat patients with VEN. The purpose of this study was to report our experience treating VEN using a PS 532-nm laser. We present a retrospective case series of six patients with large VEN who were treated using a PS 532-nm laser (2-6 treatments, 8-10 weeks apart). Response in clinical photographs was assessed by two independent dermatologists and graded on a scale of 0 (exacerbation) to 4 (76-100% improvement). Patient satisfaction was recorded on a scale of 1-5. All patients demonstrated significant improvement. Average improvement was 3.7 on the quartile scale of improvement. Patient satisfaction rate averaged 4.7. The PS 532-nm laser is a promising novel modality for the treatment of large VEN.

Les sources littéraires des citations peintes sur les phylactères des saints de la rangée inférieure de la façade et de l’exonarthex de l’église de la Résurrection de Dieu du monastère de Suceviţa

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Constantin I. Ciobanu

2015-12-01

Full Text Available Cette étude vise à découvrir les sources littéraires des citations peintes sur les phylactères des saints de la rangée inférieure de la façade et de l’exonarthex de l’église de la Résurrection de Dieu du monastère de Suceviţa. Elle est une suite de l’article sur les sentences des pères du désert, des confesseurs, des anachorètes et des stylites peints sur la façade méridionale de l’église de l’Annonciation de la Vierge de Moldoviţa. Son objectif est de donner un aperçu précis sur la variété des sources littéraires qui ont été choisies par les auteurs du programme iconographique du dernier ensemble de peintures murales extérieures moldaves peintes au XVIe siècle. L’auteur de l’étude montre que ces citations de Suceviţa sont en grande partie tirées de la Collection alphabétique des Sentences des Pères du Désert. Cette Collection alphabétique a le rôle joué au monastère de Moldoviţa par la sélection des sources grecques primaires de la traduction russe du XIXe siècle faite par Théophane le Reclus et appelée par celui-ci Paterikon palestinien. La paternité des ces citations est plus ou moins arbitraire à Suceviţa : nous observons une attribution correcte seulement dans les cas des images des saints Antoine, Nil, Arsène, Étienne le Nouveau, Barlaam et Isaïe. De ce point de vue, la situation est semblable à celle observée aux monastères de Humor et de Moldoviţa. Dans le programme iconographique de Suceviţa il y a plusieurs répétitions des mêmes citations : elles sont attribuées à divers ou aux mêmes saints. C’est le cas des citations de Saint Chariton et de Saint Daniel le Stylite, de Saint Cyriaque l’Anachorète et de Saint Patapios, de Saint Athanase l’Athonite et de Saint Jean le Calybite, de Saint Nil et de Saint Gérasime, de Saint Jean Damascène (qui est peint deux fois : sur la façade sud et dans l’exonarthex, de Saint Théodore le Confesseur et de Saint Th

Analysis of the effects of human activities on the hydromorphological evolution channel of the Saint-Maurice River downstream from La Gabelle dam (Quebec, Canada)

Science.gov (United States)

Vadnais, Marie-Ève; Assani, Ali A.; Landry, Raphaëlle; Leroux, Denis; Gratton, Denis

2012-11-01

During the first half of the twentieth century, many hydroelectric facilities were built in the Saint-Maurice River watershed, followed by other human activities in the second half of the century (pleasure boating, boom dismantling, urbanization, etc.). The goal of the study is to constrain the effects of these various types of human activities, particularly those of the many dams in the watershed, on the hydromorphological evolution of the Saint-Maurice River downstream from the La Gabelle (dam) power plant (43,000 km2). Comparison of specific discharge in this river with streamflow measured in a natural river setting reveals a significant decrease in seasonal maximum flows, aside from winter, when daily maximum flows increased significantly. Also, unlike natural rivers, the long-term trend in spring flows is not characterized by a significant change in mean downstream from the La Gabelle plant. These hydrological changes are linked to the inversion-type management mode of the reservoirs built downstream from the plant. As for the morphological evolution, the longitudinal variability of bankfull width downstream from the plant shows two significant shifts in mean: the first, which was quasi-abrupt, took place downstream of the des Forges rapid; and the second, which was gradual, occurred upstream from the confluence of the Saint-Maurice River with the St. Lawrence River, above the point where the Saint-Maurice splits into two branches. Comparison of aerial photographs taken at various times (1948, 1964, 1975, 1996, and 2008) reveals no significant change in the mean of bankfull width over time. However, a significant increase in the surface area of islets located at the confluence was observed, which is caused by sediment accumulation. These sediments were likely derived from local bank erosion resulting from anthropogenic changes.

Saint Petersburg as a Global Coastal City: Positioning in the Baltic Region

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Lachininskii Stanislav

2015-09-01

Full Text Available The Baltic region consists of coastal areas of nine countries — Russia, Estonia, Latvia, Lithuania, Poland, Germany, Denmark, Sweden, and Finland. The region’s hubs are the port cities located along the Baltic Sea coast. However, Peter Taylor and Saskia Sassen’s classification identifies higher status cities and ‘global cities’, which are to be considered in the global context. Seven coastal regions are distinguished within this region, whose organising centers are the global coastal cities of Stockholm, Copenhagen, Helsinki, Riga, Tallinn, St. Petersburg, and Malmö. The concept of a “global city-region” (Sassen can be used as a methodological framework for analyzing this connection. Within this hierarchy, the dominant alpha group global city is Stockholm. The authors argue that, as a global coastal city, St. Petersburg forms the St. Petersburg coastal region, which can be defined as a typical "global city region". The index method shows that the position of St. Petersburg in the system of global coastal cities of the Baltic region is relatively favorable in view of its transport, logistics, and demographic potential and the advantageous geo-economic situation. St. Petersburg has certain competitive advantages in the region brought about by its demographic potential, port freight capacity, and the favorable geo-economic position of the "sea gate" of Russia. However, the level of high-tech services and ‘new economy’ development is not sufficient for the port to become a match for the top three cities (Stockholm, Helsinki, and Copenhagen. This is increasingly important because transboundary global city networks demonstrate that global cities are functions of global networks. Saint Petersburg is just starting to integrate into these networks through the Pulkovo airline hub and seaports of Ust-Luga, Primorsk, and Saint Petersburg.

Saint Petersburg as a Global Coastal City: Positioning in the Baltic Region

Directory of Open Access Journals (Sweden)

Lachninsky S.

2015-08-01

Full Text Available The Baltic region consists of coastal areas of nine countries — Russia, Estonia, Latvia, Lithuania, Poland, Germany, Denmark, Sweden, and Finland. The region’s hubs are the port cities located along the Baltic Sea coast. However, Peter Taylor and Saskia Sassen’s classification identifies higher status cities and ‘global cities’, which are to be considered in the global context. Seven coastal regions are distinguished within this region, whose organising centers are the global coastal cities of Stockholm, Copenhagen, Helsinki, Riga, Tallinn, St. Petersburg, and Malmö. The concept of a “global city-region” (Sassen can be used as a methodological framework for analyzing this connection. Within this hierarchy, the dominant alpha group global city is Stockholm. The authors argue that, as a global coastal city, St. Petersburg forms the St. Petersburg coastal region, which can be defined as a typical "global city region". The index method shows that the position of St. Petersburg in the system of global coastal cities of the Baltic region is relatively favorable in view of its transport, logistics, and demographic potential and the advantageous geo-economic situation. St. Petersburg has certain competitive advantages in the region brought about by its demographic potential, port freight capacity, and the favorable geo-economic position of the "sea gate" of Russia. However, the level of high-tech services and ‘new economy’ development is not sufficient for the port to become a match for the top three cities (Stockholm, Helsinki, and Copenhagen. This is increasingly important because transboundary global city networks demonstrate that global cities are functions of global networks. Saint Petersburg is just starting to integrate into these networks through the Pulkovo airline hub and seaports of Ust-Luga, Primorsk, and Saint Petersburg.

La fouille du fort Saint-Georges à Chinon (Indre-et-Loire. Premiers résultats The excavation of fort Saint-Georges at Chinon (Indre-et-Loire. First results

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Bruno Dufaÿ

2006-05-01

Full Text Available Cette note présente les premiers résultats des fouilles menées en 2003 et 2004 sur la quasi-totalité du fort Saint-Georges à Chinon (Indre-et-Loire. Celui-ci est l’un des trois éléments de la forteresse médiévale qui domine la ville. La fouille a permis de préciser la fonction du fort, construit dans la deuxième moitié du XIIe s., à l’époque où Chinon est le centre administratif des possessions continentales des Plantagenêt, rois d’Angleterre. Du point de vue militaire, il formait une fortification avancée, protégeant le château principal, selon une structure que Richard Cœur de Lion appliquera au Château Gaillard. À l’intérieur, de vastes bâtiments constituaient des logis, conçus peut-être au départ pour héberger la chancellerie royale.This article presents the first results of the excavations undertaken in 2003 and 2004 over almost all of the Fort Saint-Georges at Chinon (Indre-et-Loire, one of three elements of the medieval fortress which dominates the town. The excavation enabled us to clarify the function of the fort, built in the 2nd half of the 12th century at a time when Chinon was the administrative centre of the continental possesions of the Plantagenet King of England. From a military point of view, it formed an advanced fortification protecting the main castle, within a structure that Richard the Lionheart would apply to the Chayeau Gaillard. Inside, some vast buildings made up the dwellings, designed perhaps initially to house the royal chanceller.

Pigmentary Markers in Danes--Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome.

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Peter Johansen

Full Text Available To investigate whether pigmentation genes involved in the melanogenic pathway (melanogenesis contributed to melanoma predisposition, we compared pigmentary genetics with quantitative skin pigmentation measurements, the number of atypical nevi, the total nevus count, and the familial atypical multiple mole and melanoma (FAMMM syndrome. We typed 32 pigmentary SNP markers and sequenced MC1R in 246 healthy individuals and 116 individuals attending periodic control for malignant melanoma development, 50 of which were diagnosed with FAMMM. It was observed that individuals with any two grouped MC1R variants (missense, NM_002386:c. 456C > A (p.TYR152*, or NM_002386:c.83_84insA (p.Asn29Glnfs*14 had significantly (p<0.001 lighter skin pigmentation of the upper-inner arm than those with none or one MC1R variant. We did not observe any significant association of the MC1R variants with constitutive pigmentation measured on the buttock area. We hypothesize that the effect of MC1R variants on arm pigmentation is primarily reflecting the inability to tan when subjected to UVR. A gender specific effect on skin pigmentation was also observed, and it was found that the skin pigmentation of females on average were darker than that of males (p<0.01. We conclude that MC1R variants are associated with quantitative skin colour in a lightly pigmented Danish population. We did not observe any association between any pigmentary marker and the FAMMM syndrome. We suggest that the genetics of FAMMM is not related to the genetics of the pigmentary pathway.

How Doubt Built the Foundation of the Church of Jesus Christ of Latter-Day Saints

OpenAIRE

Hortin, Joshua

2013-01-01

Dr. Gregory A. Prince at this year’s annual Arrington Lecture gave an intriguing biography of Leonard J. Arrington, focusing particularly on Arrington’s own interplay between faith and doubt. Arrington’s intellectual journey was sparked as he entered the world of academia and had his beliefs on evolution directly challenged. Having been raised as a member of the Church of Jesus Christ of Latter-­‐ day Saints (LDS or Mormon), he struggled with reconciling a Creationist viewpoint to that taught...

Saint Agatha Religious Festival in Catania: Stakeholders’ Functions and Relations

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Salvatore Cannizzaro

2017-03-01

Full Text Available The purpose of the paper is to develop an explorative analysis of the functions and relations among actors involved in the organization and implementation of the Saint Agatha Religious Festival in Catania attracting nearly one million presences during the first week of February. The research is based on the survey of different sources of information, such as literature, news, media, and deep interviews with key informants pertaining to civil and religious institutions. The survey is designed to profile the Festival in terms of history, the character of the stakeholders, size, origin of assets, venues used, decision-making structure, and programs. The Festival’s use of volunteers and sponsors is specifically addressed. Empirical research sketches the network of stakeholders, the relationship between organizations, the importance of local social actors and strategies in enhancing local culture and sustainable tourism, regarding, in particular, the socio-cultural impacts of religious tourism. The local society has historical peculiarities which impose prudential considerations in generalizing about findings, and a comparative study with other Sicilian and/or Italian religious festivals will be important, mainly in order to delineate the actual sustainability of Festivals. The framework developed in this study can be helpful in the application of local social policies and also help comparative festival studies.

Campaign of complementary investigation on the old mining site of Saint-Pierre (Cantal) 2. part of the relative expertise at the radiological situation of the site; Campagne d'investigations complementaires sur l'ancien site minier de Saint Pierre (Cantal) Volet 2 de l'expertise relative a l'etat radiologique du site

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01

The C.L.I. of Saint-Pierre which was held on May 19., 2006 in Mauriac (Cantal) confirmed the program of additional investigations to be collectively led by the I.R.S.N. and the C.R.I.I.R.A.D. on Saint Pierre site. Main directions are the following ones: realize additional analyses on the drainages of water; measure the external exposure on 14 plots of land; measure the flux of radon at the ground level and radon inside houses; realize investigations on the food chain. The present report reports campaigns of sampling realized by the I.R.S.N. in 2006 as well as analyses led in its laboratories. (N.C.)

Life of saint Spiridon and history on relic to the bishop of Tremithus

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Adam Magruk

2015-11-01

Full Text Available In the last few years Saint Spyridon – the great hierarch of Greek Orthodox Church, is becoming increasingly known, glorified and praised by Orthodox Christians from all over the world including slavic territories. In Russia, for instance, St Spyridon is honored on a par with St Nikolaos the Wonderworker. Therefore, his biography is truly admirable, e.g. occurrences before the ordination to the priesthood and even more interestingly facts after he was made Bishop of Trimythous. St Spyridon participated in the sessions of the Firts Ecumenical Council, where he played a significant and remarkable role. Special attention deserve also the history of St Spyridon’s relics, which repose on the Greek island of Corfu to this day as well as his miraculous right hand returned to Orthodox Greeks by Catholic Church after c. 800 years.

Puentes de Saint-André-de-Cubzac y de Angers Francia

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Mathivat, J.

1978-02-01

Full Text Available The development of the technique of prefabricated voussoir bridges during the past years has been made possible by the progress achieved in various fields which are developed here, namely: 1 the improvement of the joint between arch stones by the adoption of multiplenotch joints where the adhesive plays a less important part, 2 the increase ín the cross dimensions of the voussoirs as well as in their unit weight, which reduces the number of joints, as well as the diversification of the forms, which can lead to the elimination of the cross prestress, 3 the improvement of the methods of placing and of the design of the lifting rigs: mobile lifting equipement carried by the deck, launching girder. The study of these different factors is supplemented and illustrated by the presentation of two recent works: the freeway bridges of Saint-André-de-Cubzac and the bridge on the Loire near Angers.

El desarrollo de la técnica de los puentes de dovelas prefabricadas ha experimentado un fuerte incremento, durante los últimos años, a causa de: 1 Mejoramiento de las juntas entre dovelas, por adopción de sistemas dotados de dentado múltiple, en cuyo caso el papel de la cola es menos primordial. 2 Aumento de las dimensiones transversales de las dovelas, así como de su peso unitario, lo cual reduce el número de juntas, así como la diversificación de las formas, con lo cual se puede conseguir la supresión del pretensado transversal. 3 Mejoras introducidas en los métodos de colocación y en el diseño de los aparatos de elevación: equipo móvil de elevación soportado por el propio tablero, viga de lanzamiento. El estudio de estos distintos factores se ha ilustrado con la presentación de dos obras recientemente ejecutadas, a saber: los puentes de autopista de Saint-André-de-Cubzac y el puente del Loira, cerca de Angers.

Les ombres noires de Saint Domingue: The Impact of Black Women on Gender and Racial Boundaries in Eighteenth- and Nineteenth-Century France

OpenAIRE

Mitchell, Robin

2010-01-01

AbstractLes ombres noires de Saint Domingue: The Impact of Black Women on Gender & Racial Boundaries in Eighteenth- and Nineteenth-Century FrancebyRobin MitchellDoctor of Philosophy in HistoryUniversity of California, BerkeleyProfessor Tyler Stovall, ChairThere were few black women on French soil in the nineteenth century, yet images of and discussions about them are found in political, artistic, scientific, and various social milieus. This paradox is explored for its symbolic and nationali...

Geographic distribution of ebony leaf monkey Trachypithecus auratus (E. Geoffroy Saint-Hilaire, 1812) (Mammalia: Primates: Cercopithecidae)

OpenAIRE

Nijman, Vincent

2000-01-01

As one of the fundamental units of ecology and biogeography, the geographic distribution of the endemic and threatened ebony leaf monkey Trachypithecus auratus (E. Geoffroy Saint-Hilaire, 1812) on the islands of Java, Bali, and Lombok (Indonesia) has been assessed. All localities where the species has been collected are listed, and forty-two areas (each in itself consisting of numerous smaller sites) where the species has been recorded are discussed. The species occurs in a large variety of f...

Well-balanced positivity preserving central-upwind scheme on triangular grids for the Saint-Venant system

KAUST Repository

Bryson, Steve

2010-10-11

We introduce a new second-order central-upwind scheme for the Saint-Venant system of shallow water equations on triangular grids. We prove that the scheme both preserves "lake at rest" steady states and guarantees the positivity of the computed fluid depth. Moreover, it can be applied to models with discontinuous bottom topography and irregular channel widths. We demonstrate these features of the new scheme, as well as its high resolution and robustness in a number of numerical examples. © EDP Sciences, SMAI, 2010.

Well-balanced positivity preserving central-upwind scheme on triangular grids for the Saint-Venant system

KAUST Repository

Bryson, Steve; Epshteyn, Yekaterina; Kurganov, Alexander; Petrova, Guergana

2010-01-01

We introduce a new second-order central-upwind scheme for the Saint-Venant system of shallow water equations on triangular grids. We prove that the scheme both preserves "lake at rest" steady states and guarantees the positivity of the computed fluid depth. Moreover, it can be applied to models with discontinuous bottom topography and irregular channel widths. We demonstrate these features of the new scheme, as well as its high resolution and robustness in a number of numerical examples. © EDP Sciences, SMAI, 2010.

The SARA Consortium: Providing Undergraduate Access to a 0.9-m Telescope at Kitt Peak National Observatory

Science.gov (United States)

Wood, M. A.

2003-12-01

The Southeastern Research for Astronomy (SARA) operates a 0.9-m telescope at Kitt Peak National Observatory (KPNO). The member institutions are Florida Institute of Technology, East Tennessee State University, Florida International University, The University of Georgia at Athens, Valdosta State University, and Clemson University. The NSF awarded the KPNO #1 0.9-m telescope to the SARA Consortium in 1990. We built a new facility and began routine on-site observations in 1995. We began routine remote observations in 1999 using VNC to export the telescope and CCD control screens, and a web-cam in the dome to provide critical visual feedback on the status of the telescope and dome. The mission of the SARA Consortium is to foster astronomical research and education in the Southeastern United States. Although only two of the member institutions have no graduate programs, all six have a strong emphasis on undergraduate research and education. By pooling our resources, we are able to operate a research-grade facility that none of the individual schools could manage by itself, and in the process we can offer our undergraduate students the opportunity to assist in our research projects as well as to complete their own independent research projects using a facility at a premier site. The SARA Consortium also hosts a NSF REU Summer Intern Program in Astronomy, in which we support 11-12 students that work one-on-one with a SARA faculty mentor. Most of these interns are selected from primarily undergraduate institutions, and have not had significant previous research experience. As part of the program, interns and mentors travel to KPNO for a 4-5 night observing run at the telescope. The SARA NSF REU Program is funded through NSF grant AST-0097616.

Le monastère Saint-Pierre d’Osor (île de Cres, Croatie : quatrième campagne d’études archéologiques

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Sébastien Bully

2010-10-01

Full Text Available Comme chaque année depuis 2006, le site du monastère Saint-Pierre d’Osor a fait l’objet d’une nouvelle campagne de fouilles archéologiques durant trois semaines, du 11 au 30 mai 2009 . Le chantier de fouilles a été suivi par une campagne de prospection géophysique du 22 au 25 février 2010, conformément au programme convenu en 2008 avec le Service pour la protection des monuments historiques de Rijeka . Avec l’achèvement de l’étude des élévations de l’église Saint-Pierre intervenue l’année pré...

The religious tourism in Greece: Case study of Saint John Russian in N. Evia

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Aggeliki Chantziantoniou

2017-12-01

Full Text Available The prevailing political and economic conditions both in Greece and around the world determine the general development of all forms of tourism. The development of specific forms of tourism, such as that of religious tourism, gains tremendous interest in the present economic circumstances, as it is a factor in strengthening the national economy and at the same time a legacy for the future with enormous social, cultural and environmental significance. The development of a strategic approach to religious tourism can build on the comparative advantage of our country in this field by creating new tourist sites to attract tourists with intellectual pursuits and special interests. The Prefecture of Evia has a rich range of natural and cultural resources, with particular characteristics of beauty, uniqueness, and authenticity, elements that are required for the design and development of specific forms of tourism. In the case study on religious tourism in Saint John Russian in the Prefecture of Evia, an attempt is being made to explore the contribution of religious tourism tolocaldevelopmentandthepreconditionsforthepromotionofthepilgrimageof SaintJohn Russian to a major destination of religious and cultural interest of international scope. Additionally, an effort is made to highlight the importance of religious tourism as a special form of tourism that contributes to the development of areas hosting religious monuments. Identifying the opportunities and opportunities that exist, exploring its growth prospects and identifying emerging markets, dictates the formulation of policy proposals where combined with the existing specific forms of tourism it will show it as an essential factor in the systematic organization, exploitation and promotion of the Area.

Saint Louis Center for Sustainment of Trauma and Readiness Skills: A Collaborative Air Force-Civilian Trauma Skills Training Program

Science.gov (United States)

2016-05-19

NUMBER 6. AUTHOR(S) Jason W. Grimm , Karen Johnson 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION...ABSTRACT SAR 18. NUMBER OF PAGES 5 19a. NAME OF RESPONSIBLE PERSON Jason Grimm a. REPORT U b. ABSTRACT U c. THIS PAGE U 19b... Grimm Karen Johns For correspo Vista at Gra J Emerg Nu 0099-1767 Published b http://dx.do ■ ■ • ■SAINT LOUIS CENTER FOR SUSTAINMENT OF TRAUMA AND

Premalignant quiescent melanocytic nevi do not express the MHC class I chain-related protein A Los nevos melanocíticos premalignos quiescentes no expresan la molécula MHC class I chain-related protein A

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Mercedes B. Fuertes

2011-08-01

Full Text Available The MHC class I chain-related protein A (MICA is an inducible molecule almost not expressed by normal cells but strongly up-regulated in tumor cells. MICA-expressing cells are recognized by natural killer (NK cells, CD8+ aßTCR and ?dTCR T lymphocytes through the NKG2D receptor. Engagement of NKG2D by MICA triggers IFN-? secretion and cytotoxicity against malignant cells. Although most solid tumors express MICA and this molecule is a target during immune surveillance against tumors, it has been observed that high grade tumors from different histotypes express low amounts of cell surface MICA due to a metalloprotease- induced shedding. Also, melanomas develop after a complex process of neotransformation of normal melanocytes. However, the expression of MICA in premalignant stages (primary human quiescent melanocytic nevi remains unknown. Here, we assessed expression of MICA by flow cytometry using cell suspensions from 15 primary nevi isolated from 11 patients. When collected material was abundant, cell lysates were prepared and MICA expression was also analyzed by Western blot. We observed that MICA was undetectable in the 15 primary nevi (intradermic, junction, mixed, lentigo and congenital samples as well as in normal skin, benign lesions (seborrheic keratosis, premalignant lesions (actinic keratosis and benign basocellular cancer. Conversely, a primary recently diagnosed melanoma showed intense cell surface MICA. We conclude that the onset of MICA expression is a tightly regulated process that occurs after melanocytes trespass the stage of malignant transformation. Thus, analysis of MICA expression in tissue sections of skin samples may constitute a useful marker to differentiate between benign and malignant nevi.MHC class I chain-related protein A (MICA es una molécula casi ausente en células normales pero sobre-expresada por células tumorales, que promueve el reconocimiento por células citotóxicas naturales (natural killer o NK y por

Risk behaviours and healthcare needs of homeless drug users in Saint Lucia and Trinidad.

Science.gov (United States)

Day, Marcus; Devieux, Jessy G; Reid, Sandra D; Jones, Dionne J; Meharris, Joseph; Malow, Robert M

2004-01-01

In the Caribbean AIDS has become the leading cause of death among those aged 15-45. The homeless are at high risk due to the nexus of mobility, psychiatric disorders and substance use, particularly crack. Seventy-four homeless, out-of-treatment drug users were recruited in Saint Lucia and Trinidad to assess risk behaviour and healthcare needs. Information was collected in several domains: medical, mental health, substance use, sexual risk, and barriers to care. Ninety-five percent of the sample reported crack cocaine use within the previous 30 days. Approximately 35% of the sample had ever been diagnosed with a sexually transmitted disease and 25% of the sample reported being HIV+. Approximately 40% had a history of trading sex for crack or money. Due to the range of needs in this population, interventions should be multimodal. A focus on the individual, community, and structural levels is warranted to improve chances of program effectiveness.

La collégiale de Saint-Bonnet-le-Château (Loire

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Bernard Ducouret

2012-04-01

Full Text Available La collégiale de Saint-Bonnet-le-Château est principalement connue pour les peintures murales du XVe siècle qui décorent sa chapelle basse, dont une partie est reproduite au musée des Monuments français, et, à un moindre degré, pour sa bibliothèque qui conserve de nombreux incunables. Son architecture, plus ignorée, n'en est pas moins digne d'intérêt. Nous ne présenterons pas ici l'ensemble de l'édifice, négligeant des éléments remarquables comme le porche sud (cf. plan, au-dessous de la sacr...

Initial experiments with the Nevis Cyclotron, the Brookhaven Cosmotron, the Brookhaven AGS and their effects on high energy physics

International Nuclear Information System (INIS)

Lindenbaum, S.J.

1988-01-01

The first experiment at the Nevis Cyclotron by Bernardini, Booth and Lindenbaum demonstrated that nuclear stars are produced by a nucleon-nucleon cascade within the nucleon. This solved a long standing problem in Cosmic rays and made it clear that where they overlap cosmic ray investigation would not be competitive with accelerator investigations. The initial experiments at the Brookhaven Cosmotron by Lindenbaum and Yuan demonstrated that low energy pion nucleon scattering and pion production were unexpectedly mostly due to excitation of the isotopic spin = angular momentum = 3/2 isobaric state of the nucleon. This contradicted the Fermi statistical theory and led to the Isobar model proposed by the author and a collaborator. The initial experiments at the AGS by the author and collaborators demonstrated that the Pomeronchuck Theorem would not come true till at least several hundred GeV. These scattering experiments led to the development of the ''On-line Computer Technique'' by the author and collaborators which is now the almost universal technique in high energy physics. The first accomplishment which flowed from this technique led to contradiction of the Regge pole theory as a dynamical asymptotic theory, by the author and collaborators. The first critical experimental proof of the forward dispersion relation in strong interactions was accomplished by the author and collaborators. They were then used as a crystal ball to predict that ''Asymptopia''---the theoretically promised land where all asymptotic theorems come true---would not be reached till at least 25,000 BeV and probably not before 1,000,000 BeV. 26 refs., 11 figs., 2 tabs

Southeast Indian Ridge Between the Rodriguez Triple Junction and the Amsterdam and Saint-Paul Islands: Detailed Kinematics for the Past 20 m.y.

Science.gov (United States)

Royer, Jean-Yves; Schlich, Roland

1988-11-01

The Southeast Indian Ridge has the fastest spreading rates of the three mid-oceanic ridge systems of the Indian Ocean and has recorded the movements of Antarctica relative to Australia and India since the Late Cretaceous. New bathymetric and magnetic data have been collected by the R/V Marion Dufresne (1983) and the R/V Jean Charcot (1984), on the western part of this ridge, between the Rodriguez Triple Junction (25.5°S, 70.0°E) and the Amsterdam and Saint-Paul islands (38°S, 78°E). These data bring additional information on the seafloor magnetic pattern produced by the Southeast Indian Ridge during the past 20 m.y. A new tectonic chart is proposed for the area around the Amsterdam and Saint-Paul islands. We have mapped 17 isochrons ranging from anomalies 6 to 1 (20.5-0.7 Ma) based on the compilation of all the data available in this area (25 cruises). Their distribution clearly shows asymmetric features. Reconstructions at short time intervals show that stage poles of rotation describe oscillatory movements along a direction parallel to the Southeast Indian Ridge axis. Observed changes in spreading rates and the stability of the spreading directions since the Miocene support this result.

Advice about the safety of graphite storage silos of Saint Laurent des Eaux facility; Avis sur la surete des silos de stockage de graphite de Saint Laurent des Eaux

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

This document is the safety analysis made by the national association of the local commissions of information about nuclear activities (ANCLI), about the safety of graphite storage silos of Saint Laurent des Eaux nuclear facility. The analysis covers: the operation safety and the accident hypothesis, the monitoring of indoor and outdoor contamination in routine situation, the geotechnical characteristics of the site environment, the isotopic inventory and the estimation of radioactivity in routine and accidental situation, the estimation of doses received by the population in accidental situation and the internal emergency plan. After examination of these different points, the scientific committee of the ANCLI considers that a new global evaluation of risks, which integrates more recent exposure data, has to be carried out. (J.S.)

Campaign of complementary investigation on the old mining site of Saint-Pierre (Cantal) 2. part of the relative expertise at the radiological situation of the site

International Nuclear Information System (INIS)

2007-01-01

The C.L.I. of Saint-Pierre which was held on May 19., 2006 in Mauriac (Cantal) confirmed the program of additional investigations to be collectively led by the I.R.S.N. and the C.R.I.I.R.A.D. on Saint Pierre site. Main directions are the following ones: realize additional analyses on the drainages of water; measure the external exposure on 14 plots of land; measure the flux of radon at the ground level and radon inside houses; realize investigations on the food chain. The present report reports campaigns of sampling realized by the I.R.S.N. in 2006 as well as analyses led in its laboratories. (N.C.)

A Collaborative Approach to Monitoring Ambient Volcanogenic Pollution at Sulphur Springs, Saint Lucia.

Science.gov (United States)

Joseph, E. P.; Beckles, D. M.; Cox, L.; Jackson, V. B.; Alexander, D.

2015-12-01

The role of volcano tourism is recognized as an important contributor to the economy of volcanic islands in the Lesser Antilles. However, if it is to be promoted as a sustainable sector of the tourism industry, visitors, tour operators, and vendors must be made aware of the potential health hazards facing them in volcanic environments. Volcanogenic air pollutants are of primary concern in this setting. In general, no warning signs, guidelines for recreational use, or emissions monitoring currently exists to provide warning to the public to decrease their vulnerability to the potential risks, or to minimize the liability of the agencies managing these areas. Sulphur Springs Park in Saint Lucia is a popular international destination, and concerns about the volcanic emissions and its possible health effect have been raised by visitors, staff, and management of the Park. As part of the responsibility of the UWI, Seismic Research Centre (SRC) to provide volcanic surveillance through its geothermal monitoring programme, a network was established for quantifying the ambient SO2 concentrations at Sulphur Springs in order to assess the potential risk of unsafe exposure. This effort required collaboration with the National Emergency Management Organization (NEMO) of Saint Lucia, as well as the staff and management of the Soufrière Regional Development Foundation (SRDF). Local personnel were trained in the active field sampling and analytical techniques required for the assessment of ambient SO2 concentrations over the monitoring period, thereby contributing to an active community-based effort. This type of approach was also thought to be an effective option for scientists to engage communities as partners in disaster risk reduction. Lessons learnt from this experience are presented for the benefit of other citizen monitoring projects, including its use as a tool for promoting volcanic hazard education, and enhancing communication and understanding between geoscientists and

A geologic guide to Wrangell-Saint Elias National Park and Preserve, Alaska; a tectonic collage of northbound terranes

Science.gov (United States)

Winkler, Gary R.; with contributions by MacKevett, E. M.; Plafker, George; Richter, D.H.; Rosenkrans, D.S.; Schmoll, H.R.

2000-01-01

Wrangell-Saint Elias National Park and Preserve, the largest unit in the U.S. National Park System, encompasses near 13.2 million acres of geological wonderments. This geologic guide presents history of exploration and Earth-science investigation; describes the complex geologic makeup; characterizes the vast college of accretion geologic terranes in this area of Alaska's continental margin; recapitulates the effects of earthquakes, volcanoes, and glaciers; characterizes the copper and gold resources of the parklands; and describes outstanding locales within the park and preserve area. A glossary of geologic terms and a categorized list of additional sources of information complete this report.

The economics of geothermal power in Saint Lucia, West Indies

International Nuclear Information System (INIS)

Barthelmy, A.

1990-01-01

This paper reports on an economic comparison which is made between geothermal power at Sulphur Springs, Soufriere, Saint Lucia and diesel generated power from a new diesel power station at Cul de Sac to the south of Castries. The comparison is over a 20 year period. The new diesel power station is scheduled for commission during the second half of 1990. The capital costs for the Cul de Sac Station are based on actual contract sums for Stage I of the development program, comprising 2 x 6.3 MW generating units. Development costs for a 2 x 5.6 MW dry steam geothermal power plant are based on actual well costs and estimated costs for the steam gathering system and power plant. The geothermal reservoir is assumed to be vapor dominated. Levelized coatings will be adopted for comparing the total generating costs in cents per kilowatt hour associated with the two generating plants

Radiological status of the Saint-Pierre (Cantal) uranium mine and of its environment. Volume 1 + volume 2 + volume 3

International Nuclear Information System (INIS)

2006-01-01

The first volume reports detailed investigations performed by the CRIIRAD (sampling and radiological controls of sediments, and more particularly of waters and aquatic plants) in different areas about the Saint-Pierre uranium mine in France (Cantal department). Measurements were performed by gamma spectrometry. The second part concerns external exposure and the radiological characterization of soils. The third part reports the study of the presence of radon in outdoor and indoor air. For each of these aspects, methodological information is given as well as a great quantity of measurement results